BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= AAB46420.1__[Trypanosoma_brucei]
(512 letters)
Database: nr.pal
6,348,806 sequences; 2,166,943,470 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|1708476|sp|P50098|IMDH_TRYBB Inosine-5'-monophosphate de... 1021 0.0
gi|71749484|ref|XP_828081.1| inosine-5'-monophosphate dehyd... 885 0.0
gi|71406474|ref|XP_805772.1| inosine-5'-monophosphate dehyd... 870 0.0
gi|71653712|ref|XP_815489.1| inosine-5'-monophosphate dehyd... 865 0.0
gi|146084871|ref|XP_001465126.1| inosine-5'-monophosphate d... 808 0.0
gi|157868384|ref|XP_001682745.1| inosine-5'-monophosphate d... 807 0.0
gi|38326707|gb|AAR17482.1| inosine 5' monophosphate dehydro... 807 0.0
gi|154336078|ref|XP_001564275.1| inosine-5'-monophosphate d... 804 0.0
gi|56207809|emb|CAI21140.1| novel protein similar to verteb... 561 e-158
gi|94732689|emb|CAK04261.1| novel protein similar to verteb... 557 e-157
gi|148222892|ref|NP_001082410.1| similar to inosine 5'-phos... 556 e-156
gi|119891311|ref|XP_001252299.1| PREDICTED: inosine monopho... 553 e-155
gi|50345008|ref|NP_001002177.1| hypothetical protein LOC431... 553 e-155
gi|62122931|ref|NP_001014391.1| hypothetical protein LOC338... 553 e-155
gi|71895387|ref|NP_001025772.1| inosine monophosphate dehyd... 552 e-155
gi|118150800|ref|NP_001071309.1| inosine monophosphate dehy... 550 e-155
gi|34328928|ref|NP_899066.1| inosine monophosphate dehydrog... 549 e-154
gi|62859741|ref|NP_001017283.1| IMP (inosine monophosphate)... 549 e-154
gi|156616279|ref|NP_001096075.1| inosine monophosphate dehy... 548 e-154
gi|25014074|sp|P20839|IMDH1_HUMAN Inosine-5'-monophosphate ... 548 e-154
gi|34328930|ref|NP_000874.2| inosine monophosphate dehydrog... 548 e-154
gi|119585350|gb|EAW64946.1| hCG2002013, isoform CRA_a [Homo... 548 e-154
gi|307066|gb|AAA36112.1| inosine-5'-monophosphate dehydroge... 548 e-154
gi|147904959|ref|NP_001080792.1| inosine 5'-phosphate dehyd... 548 e-154
gi|119604058|gb|EAW83652.1| IMP (inosine monophosphate) deh... 548 e-154
gi|109039747|ref|XP_001110855.1| PREDICTED: inosine monopho... 548 e-154
gi|66933016|ref|NP_000875.2| inosine monophosphate dehydrog... 547 e-154
gi|148681842|gb|EDL13789.1| inosine 5'-phosphate dehydrogen... 547 e-154
gi|169158048|emb|CAQ13978.1| IMP (inosine monophosphate) de... 546 e-153
gi|34328209|ref|NP_035959.2| inosine 5'-phosphate dehydroge... 546 e-153
gi|73985586|ref|XP_850933.1| PREDICTED: similar to inosine ... 546 e-153
gi|56118558|ref|NP_001008066.1| IMP (inosine monophosphate)... 546 e-153
gi|149065132|gb|EDM15208.1| IMP (inosine monophosphate) deh... 546 e-153
gi|149728911|ref|XP_001494600.1| PREDICTED: similar to hCG2... 546 e-153
gi|77735779|ref|NP_001029588.1| IMP (inosine monophosphate)... 545 e-153
gi|33357127|pdb|1JCN|A Chain A, Binary Complex Of Human Typ... 545 e-153
gi|148225013|ref|NP_001083990.1| inosine 5'-phosphate dehyd... 545 e-153
gi|31981382|ref|NP_035960.2| inosine 5'-phosphate dehydroge... 545 e-153
gi|309413|gb|AAA39311.1| IMP dehydrogenase (EC 1.2.1.14) 544 e-153
gi|149259047|ref|XP_001478203.1| PREDICTED: similar to Inos... 544 e-153
gi|41393093|ref|NP_958872.1| inosine monophosphate dehydrog... 544 e-153
gi|126335795|ref|XP_001367707.1| PREDICTED: similar to hCG2... 544 e-153
gi|124426|sp|P12269|IMDH2_CRIGR Inosine-5'-monophosphate de... 544 e-153
gi|74137991|dbj|BAE25403.1| unnamed protein product [Mus mu... 544 e-153
gi|126340779|ref|XP_001372080.1| PREDICTED: similar to Inos... 543 e-153
gi|1708472|sp|P50096|IMDH1_MOUSE Inosine-5'-monophosphate d... 543 e-152
gi|119604055|gb|EAW83649.1| IMP (inosine monophosphate) deh... 543 e-152
gi|425158|gb|AAA20181.1| IMP dehydrogenase 542 e-152
gi|74198797|dbj|BAE30628.1| unnamed protein product [Mus mu... 542 e-152
gi|156408461|ref|XP_001641875.1| predicted protein [Nematos... 541 e-152
gi|73985596|ref|XP_862835.1| PREDICTED: similar to Inosine-... 541 e-152
gi|307067|gb|AAA36114.1| IMP dehydrogenase type 1 (EC 1.1.1... 539 e-151
gi|40018566|ref|NP_954530.1| inosine monophosphate dehydrog... 539 e-151
gi|73985598|ref|XP_533835.2| PREDICTED: similar to inosine ... 538 e-151
gi|109039753|ref|XP_001110813.1| PREDICTED: inosine monopho... 537 e-151
gi|73985594|ref|XP_862810.1| PREDICTED: similar to inosine ... 537 e-151
gi|114586834|ref|XP_516452.2| PREDICTED: inosine monophosph... 535 e-150
gi|73985602|ref|XP_862898.1| PREDICTED: similar to Inosine-... 535 e-150
gi|45190723|ref|NP_984977.1| AER117Wp [Ashbya gossypii ATCC... 535 e-150
gi|66508366|ref|XP_623071.1| PREDICTED: similar to Inosine-... 533 e-150
gi|73985600|ref|XP_862874.1| PREDICTED: similar to Inosine-... 532 e-149
gi|109068124|ref|XP_001089341.1| PREDICTED: similar to inos... 532 e-149
gi|73975841|ref|XP_850999.1| PREDICTED: similar to inosine ... 531 e-149
gi|149635458|ref|XP_001505397.1| PREDICTED: similar to hCG2... 530 e-149
gi|47077068|dbj|BAD18464.1| unnamed protein product [Homo s... 530 e-149
gi|167536543|ref|XP_001749943.1| predicted protein [Monosig... 530 e-148
gi|149706201|ref|XP_001501637.1| PREDICTED: hypothetical pr... 529 e-148
gi|47220485|emb|CAG03265.1| unnamed protein product [Tetrao... 528 e-148
gi|57999523|emb|CAI45968.1| hypothetical protein [Homo sapi... 528 e-148
gi|6323585|ref|NP_013656.1| Inosine monophosphate dehydroge... 526 e-147
gi|50303677|ref|XP_451781.1| unnamed protein product [Kluyv... 525 e-147
gi|157121246|ref|XP_001653775.1| inosine-5-monophosphate de... 525 e-147
gi|151946109|gb|EDN64340.1| IMP dehydrogenase [Saccharomyce... 523 e-146
gi|58119409|gb|AAW65380.1| inosine-5'-monophosphate dehydro... 523 e-146
gi|151944202|gb|EDN62491.1| IMP dehydrogenase [Saccharomyce... 521 e-146
gi|126136759|ref|XP_001384903.1| hypothetical protein PICST... 521 e-146
gi|2497357|sp|O00086|IMDH3_CANAL Probable inosine-5'-monoph... 521 e-146
gi|170051202|ref|XP_001861658.1| inosine-5'-monophosphate d... 521 e-146
gi|148681841|gb|EDL13788.1| inosine 5'-phosphate dehydrogen... 520 e-146
gi|157820505|ref|NP_001102089.1| IMP (inosine monophosphate... 520 e-145
gi|58119404|gb|AAW65379.1| mycophenolic acid-resistant inos... 520 e-145
gi|58377269|ref|XP_309514.2| AGAP011133-PA [Anopheles gambi... 519 e-145
gi|7920698|gb|AAF70813.1|AF249293_1 putative inosine 5-mono... 518 e-145
gi|24641071|ref|NP_727441.1| raspberry CG1799-PA, isoform A... 516 e-144
gi|6322012|ref|NP_012088.1| Inosine monophosphate dehydroge... 515 e-144
gi|125983558|ref|XP_001355544.1| GA14756-PA [Drosophila pse... 513 e-143
gi|146414604|ref|XP_001483272.1| hypothetical protein PGUG_... 512 e-143
gi|6323464|ref|NP_013536.1| Inosine monophosphate dehydroge... 512 e-143
gi|50292505|ref|XP_448685.1| unnamed protein product [Candi... 511 e-143
gi|164658794|ref|XP_001730522.1| hypothetical protein MGL_2... 510 e-142
gi|109039756|ref|XP_001110769.1| PREDICTED: inosine monopho... 508 e-142
gi|91093403|ref|XP_966518.1| PREDICTED: similar to Inosine-... 508 e-142
gi|156408582|ref|XP_001641935.1| predicted protein [Nematos... 505 e-141
gi|91093401|ref|XP_975808.1| PREDICTED: similar to Inosine-... 503 e-140
gi|109130406|ref|XP_001085281.1| PREDICTED: inosine monopho... 503 e-140
gi|66810532|ref|XP_638973.1| IMP dehydrogenase [Dictyosteli... 502 e-140
gi|109039750|ref|XP_001110506.1| PREDICTED: inosine monopho... 501 e-140
gi|6467900|gb|AAF13230.1|AF196975_1 inosine 5'-monophosphat... 501 e-140
gi|73985592|ref|XP_862783.1| PREDICTED: similar to inosine ... 500 e-139
gi|50423715|ref|XP_460442.1| hypothetical protein DEHA0F020... 499 e-139
>gi|1708476|sp|P50098|IMDH_TRYBB Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH)
(IMPD)
gi|162136|gb|AAB46420.1| inosine-5'-monophosphate dehydrogenase
Length = 512
Score = 1021 bits (2639), Expect = 0.0, Method: Composition-based stats.
Identities = 512/512 (100%), Positives = 512/512 (100%)
Query: 1 MENTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLP 60
MENTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLP
Sbjct: 1 MENTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLP 60
Query: 61 LVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPD 120
LVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPD
Sbjct: 61 LVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPD 120
Query: 121 VPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMT 180
VPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMT
Sbjct: 121 VPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMT 180
Query: 181 VERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLC 240
VERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLC
Sbjct: 181 VERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLC 240
Query: 241 AAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVT 300
AAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVT
Sbjct: 241 AAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVT 300
Query: 301 QDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGG 360
QDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGG
Sbjct: 301 QDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGG 360
Query: 361 LRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRES 420
LRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRES
Sbjct: 361 LRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRES 420
Query: 421 GKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEG 480
GKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEG
Sbjct: 421 GKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEG 480
Query: 481 QVLFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
QVLFNRRTLTAQSEGAVHSLHHYERKLFASKL
Sbjct: 481 QVLFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
>gi|71749484|ref|XP_828081.1| inosine-5'-monophosphate dehydrogenase [Trypanosoma brucei TREU927]
gi|70833465|gb|EAN78969.1| inosine-5'-monophosphate dehydrogenase [Trypanosoma brucei]
Length = 447
Score = 885 bits (2286), Expect = 0.0, Method: Composition-based stats.
Identities = 446/447 (99%), Positives = 447/447 (100%)
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST
Sbjct: 1 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 60
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYP 185
IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYP
Sbjct: 61 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYP 120
Query: 186 IKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATS 245
IKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATS
Sbjct: 121 IKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATS 180
Query: 246 TREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAK 305
TREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAK
Sbjct: 181 TREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAK 240
Query: 306 NLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVG 365
NLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVG
Sbjct: 241 NLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVG 300
Query: 366 DVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYL 425
DVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYL
Sbjct: 301 DVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYL 360
Query: 426 SENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFN 485
SENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFN
Sbjct: 361 SENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFN 420
Query: 486 RRTLTAQSEGAVHSLHHYERKLFASKL 512
RR+LTAQSEGAVHSLHHYERKLFASKL
Sbjct: 421 RRSLTAQSEGAVHSLHHYERKLFASKL 447
>gi|71406474|ref|XP_805772.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma cruzi
strain CL Brener]
gi|70869309|gb|EAN83921.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma
cruzi]
Length = 512
Score = 870 bits (2247), Expect = 0.0, Method: Composition-based stats.
Identities = 417/512 (81%), Positives = 467/512 (91%)
Query: 1 MENTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLP 60
M N +LRTKT+RDG TAEELF DGL+++DFIILPGFIDF +S V VSGQFTK I LH+P
Sbjct: 1 MANVDLRTKTIRDGVTAEELFQSDGLTYSDFIILPGFIDFGASDVQVSGQFTKKIRLHIP 60
Query: 61 LVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPD 120
+VSSPMDTVTES MAR MALMGGIGV+HNNCTV+ Q +MVRSVK++RNGFIMKPKSV P+
Sbjct: 61 IVSSPMDTVTESEMARTMALMGGIGVLHNNCTVQHQVQMVRSVKMFRNGFIMKPKSVGPE 120
Query: 121 VPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMT 180
P+S I I +EKGISGILVTE G++DGKLLGIVC+KDIDFVKD S PVSQ+MT+RE+MT
Sbjct: 121 TPISVIHEINAEKGISGILVTENGRHDGKLLGIVCSKDIDFVKDVSLPVSQFMTKRESMT 180
Query: 181 VERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLC 240
VERYPI+LEEAMDVLNRSRHGYLPVLNDK EV+CLCSRRDAVRAR YPNSSLDRNGHLLC
Sbjct: 181 VERYPIRLEEAMDVLNRSRHGYLPVLNDKGEVMCLCSRRDAVRARVYPNSSLDRNGHLLC 240
Query: 241 AAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVT 300
AAATSTRE DK RVAAL+ AG+DVL+LDSSQGNT YQVSFI+WVKKT+PHLEVVAGNVVT
Sbjct: 241 AAATSTREEDKARVAALAGAGVDVLLLDSSQGNTFYQVSFIKWVKKTFPHLEVVAGNVVT 300
Query: 301 QDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGG 360
QDQAKNLIDAGAD++RIGMGSGSICITQEVLACGRPQATA+YKV RYAASRGVPC+ADGG
Sbjct: 301 QDQAKNLIDAGADAIRIGMGSGSICITQEVLACGRPQATAVYKVCRYAASRGVPCIADGG 360
Query: 361 LRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRES 420
LR+VGD+CKALA+GAN AMLGSM+AGTSETPG YFFK+G+RLK YRGMGS++AM QG+ES
Sbjct: 361 LRSVGDICKALAIGANTAMLGSMLAGTSETPGSYFFKEGLRLKAYRGMGSLEAMSQGKES 420
Query: 421 GKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEG 480
GKRYLSE ET+QVAQGV+G VLDKGSV KLLAYIHKGLQQSAQDIGE+ FDA+REK+YEG
Sbjct: 421 GKRYLSEKETVQVAQGVSGTVLDKGSVTKLLAYIHKGLQQSAQDIGEIGFDAVREKMYEG 480
Query: 481 QVLFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
QVLFNRR+ AQ EG VHSLH +E+ LF SKL
Sbjct: 481 QVLFNRRSPIAQMEGGVHSLHSFEKNLFTSKL 512
>gi|71653712|ref|XP_815489.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma cruzi
strain CL Brener]
gi|70880547|gb|EAN93638.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma
cruzi]
Length = 512
Score = 865 bits (2236), Expect = 0.0, Method: Composition-based stats.
Identities = 416/512 (81%), Positives = 467/512 (91%)
Query: 1 MENTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLP 60
M N +LRTKT+RDG TAEELF DGL+++DF+ILPGFIDF +S V VSGQFTK I LH+P
Sbjct: 1 MVNVDLRTKTIRDGVTAEELFQSDGLTYSDFVILPGFIDFGASDVQVSGQFTKKIRLHIP 60
Query: 61 LVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPD 120
+VSSPMDTVTES MAR MALMGGIGV+HNNCTV+ Q +MVRSVK++RNGFIMKPKSV PD
Sbjct: 61 IVSSPMDTVTESEMARTMALMGGIGVLHNNCTVQHQVQMVRSVKMFRNGFIMKPKSVGPD 120
Query: 121 VPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMT 180
P+S I I ++KGISGILVTE G++DGKLLGIVC+KDIDFVKD S PVSQ+MT+RE+MT
Sbjct: 121 TPISVIHEINADKGISGILVTENGRHDGKLLGIVCSKDIDFVKDVSLPVSQFMTKRESMT 180
Query: 181 VERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLC 240
VERYPI+LEEAMDVLNRSRHGYLPVLNDK EV+CLCSRRDAVRAR YPNSSLDRNGHLLC
Sbjct: 181 VERYPIRLEEAMDVLNRSRHGYLPVLNDKGEVMCLCSRRDAVRARVYPNSSLDRNGHLLC 240
Query: 241 AAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVT 300
AAATSTRE DK RVAAL+ AG+DVL+LDSSQGNTIYQVSFI+W KKT+PHLEVVAGNVVT
Sbjct: 241 AAATSTREEDKARVAALAGAGVDVLLLDSSQGNTIYQVSFIKWAKKTFPHLEVVAGNVVT 300
Query: 301 QDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGG 360
QDQAKNLIDAGAD++RIGMGSGSICITQEVLACGRPQATA+YKV RYAASRGVPC+ADGG
Sbjct: 301 QDQAKNLIDAGADAIRIGMGSGSICITQEVLACGRPQATAVYKVCRYAASRGVPCIADGG 360
Query: 361 LRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRES 420
LR+VGD+CKALA+GAN AMLGSM+AGTSETPG YFFK+G+RLK YRGMGS++AM QG+ES
Sbjct: 361 LRSVGDICKALAIGANTAMLGSMLAGTSETPGRYFFKEGLRLKTYRGMGSLEAMSQGKES 420
Query: 421 GKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEG 480
GKRYLSE ET+QVAQGV+G VLDKGSV KLLAYIHKGLQQSAQDIGE+SFDA+REK+Y G
Sbjct: 421 GKRYLSEKETVQVAQGVSGTVLDKGSVTKLLAYIHKGLQQSAQDIGEISFDAVREKMYGG 480
Query: 481 QVLFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
QVLFNRR+ AQ EG VHSLH +E+ LF SKL
Sbjct: 481 QVLFNRRSPIAQMEGGVHSLHSFEKNLFTSKL 512
>gi|146084871|ref|XP_001465126.1| inosine-5'-monophosphate dehydrogenase [Leishmania infantum JPCM5]
gi|124425|sp|P21620|IMDH_LEIDO Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH)
(IMPD)
gi|159361|gb|AAA29253.1| IMP dehydrogenase
gi|134069222|emb|CAM67369.1| inosine-5'-monophosphate dehydrogenase [Leishmania infantum]
Length = 514
Score = 808 bits (2087), Expect = 0.0, Method: Composition-based stats.
Identities = 389/510 (76%), Positives = 449/510 (88%)
Query: 3 NTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLV 62
N N R KT++DG TAEELF DGL++NDFIILPGFIDF ++ VN+SGQFTK I LH+P+V
Sbjct: 5 NANYRIKTIKDGCTAEELFRGDGLTYNDFIILPGFIDFGAADVNISGQFTKRIRLHIPIV 64
Query: 63 SSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVP 122
SSPMDT+TE+ MA+ MALMGG+GV+HNNCTVE+Q MV+SVK YRNGFI KPKSV P+ P
Sbjct: 65 SSPMDTITENEMAKTMALMGGVGVLHNNCTVERQVEMVKSVKAYRNGFISKPKSVPPNTP 124
Query: 123 VSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVE 182
+S I IK EKGISGILVTE G GKLLGIVCTKDID+VK+ PVS MTRRE MTVE
Sbjct: 125 ISNIIRIKEEKGISGILVTENGDPHGKLLGIVCTKDIDYVKNKDTPVSAVMTRREKMTVE 184
Query: 183 RYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAA 242
R PI+LEEAMDVLNRSR+GYLP++N+ DEVV LCSRRDAVRARDYP+S+LD++G L+CAA
Sbjct: 185 RAPIQLEEAMDVLNRSRYGYLPIVNENDEVVNLCSRRDAVRARDYPHSTLDKSGRLICAA 244
Query: 243 ATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQD 302
ATSTR DK RVAAL++ G+DVLVLDSSQGNTIYQ++FI+WVK TYPHLEVVAGNVVTQD
Sbjct: 245 ATSTRPEDKRRVAALADVGVDVLVLDSSQGNTIYQIAFIKWVKSTYPHLEVVAGNVVTQD 304
Query: 303 QAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLR 362
QAKNLIDAGAD +RIGMGSGSICITQEVLACGRPQ TA+YKVA+Y ASRGVPC ADGGLR
Sbjct: 305 QAKNLIDAGADGIRIGMGSGSICITQEVLACGRPQGTAVYKVAQYCASRGVPCTADGGLR 364
Query: 363 NVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGK 422
VGD+CKALA+GAN AMLG M++GT+ETPGEYFFK G+RLK YRGMGS++AM QG+ESGK
Sbjct: 365 QVGDICKALAIGANCAMLGGMLSGTTETPGEYFFKGGVRLKVYRGMGSLEAMSQGKESGK 424
Query: 423 RYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQV 482
RYLSENE +QVAQGV+G V+DKGS KL+AY+ KGLQQSAQDIGE+SFDAIREK+Y GQV
Sbjct: 425 RYLSENEAVQVAQGVSGNVVDKGSAAKLIAYVSKGLQQSAQDIGEISFDAIREKMYAGQV 484
Query: 483 LFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
LF+RR+ TAQ EG VHSLH YE+KLFA+K+
Sbjct: 485 LFSRRSPTAQGEGGVHSLHSYEKKLFAAKM 514
>gi|157868384|ref|XP_001682745.1| inosine-5'-monophosphate dehydrogenase [Leishmania major]
gi|68126200|emb|CAJ07253.1| inosine-5'-monophosphate dehydrogenase [Leishmania major]
Length = 514
Score = 807 bits (2084), Expect = 0.0, Method: Composition-based stats.
Identities = 388/510 (76%), Positives = 448/510 (87%)
Query: 3 NTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLV 62
N N R KT++DG TAEELF DGL++NDFIILPGFIDF ++ VN+SGQFTK I LH+P+V
Sbjct: 5 NANYRIKTIKDGCTAEELFRGDGLTYNDFIILPGFIDFGAADVNISGQFTKRIRLHIPIV 64
Query: 63 SSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVP 122
SSPMDT+TE+ MA+ MALMGG+GV+HNNCTVE+Q MV+SVK YRNGFI KPKSV P+ P
Sbjct: 65 SSPMDTITENEMAKTMALMGGVGVLHNNCTVERQVEMVKSVKAYRNGFISKPKSVPPNTP 124
Query: 123 VSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVE 182
+S I IK EKGISGILVTE G GKLLGIVCTKDID+VK+ PVS MTRRE MTVE
Sbjct: 125 ISNIIRIKEEKGISGILVTENGDPHGKLLGIVCTKDIDYVKNKDTPVSAVMTRREKMTVE 184
Query: 183 RYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAA 242
R PI+LEEAMDVLNRSR+GYLP++N+ EVV LCSRRDAVRARDYP+S+LD++G L+CAA
Sbjct: 185 RAPIQLEEAMDVLNRSRYGYLPIVNENGEVVNLCSRRDAVRARDYPHSTLDKSGRLICAA 244
Query: 243 ATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQD 302
ATSTR DK RVAAL++ G+DVLVLDSSQGNTIYQ++FI+WVK TYPHLEVVAGNVVTQD
Sbjct: 245 ATSTRPEDKRRVAALADVGVDVLVLDSSQGNTIYQIAFIKWVKSTYPHLEVVAGNVVTQD 304
Query: 303 QAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLR 362
QAKNLIDAGAD +RIGMGSGSICITQEVLACGRPQ TA+YKVA+Y ASRGVPC ADGGLR
Sbjct: 305 QAKNLIDAGADGIRIGMGSGSICITQEVLACGRPQGTAVYKVAQYCASRGVPCTADGGLR 364
Query: 363 NVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGK 422
VGD+CKALA+GAN AMLG M++GT+ETPGEYFFK G+RLK YRGMGS++AM QG+ESGK
Sbjct: 365 QVGDICKALAIGANCAMLGGMLSGTTETPGEYFFKGGVRLKVYRGMGSLEAMSQGKESGK 424
Query: 423 RYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQV 482
RYLSENE +QVAQGV+G V+DKGS KL+AY+ KGLQQ+AQDIGE+SFDAIREK+Y GQV
Sbjct: 425 RYLSENEVIQVAQGVSGNVVDKGSAAKLIAYVSKGLQQAAQDIGEISFDAIREKMYAGQV 484
Query: 483 LFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
LFNRR+ TAQ EG VHSLH YE+KLFA+K+
Sbjct: 485 LFNRRSPTAQGEGGVHSLHSYEKKLFAAKM 514
>gi|38326707|gb|AAR17482.1| inosine 5' monophosphate dehydrogenase [Leishmania amazonensis]
Length = 514
Score = 807 bits (2084), Expect = 0.0, Method: Composition-based stats.
Identities = 389/510 (76%), Positives = 448/510 (87%)
Query: 3 NTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLV 62
N N R KT++DG TAEELF DGL++NDFIILPGFIDF +S VN+SGQFTK I LH+P+V
Sbjct: 5 NANYRIKTIKDGCTAEELFQGDGLTYNDFIILPGFIDFGASDVNISGQFTKRIRLHIPIV 64
Query: 63 SSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVP 122
SSPMDT+TE+ MA+ MALMGG+GV+HNNCTVE+Q MV+SVK YRNGFI KPKSV P+ P
Sbjct: 65 SSPMDTITENEMAKTMALMGGVGVLHNNCTVERQVEMVKSVKAYRNGFISKPKSVPPNTP 124
Query: 123 VSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVE 182
+S I IK EKGISGILVTE G GKLLGIVCTKDID+VK+ PVS MTRRE MTVE
Sbjct: 125 ISKIIRIKEEKGISGILVTENGDPHGKLLGIVCTKDIDYVKNKDTPVSAVMTRREKMTVE 184
Query: 183 RYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAA 242
R PI+LEEAMDVLNRSR+GYLP++N+ EVV LCSRRDAVRARDYP+S+LD++G L+CAA
Sbjct: 185 RAPIQLEEAMDVLNRSRYGYLPIVNENGEVVNLCSRRDAVRARDYPHSTLDKSGRLICAA 244
Query: 243 ATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQD 302
ATSTR DK RVA L+E G+DVLVLDSSQGNTIYQ++FI+WVK TYPHLEVVAGNVVTQD
Sbjct: 245 ATSTRPEDKRRVATLAEVGVDVLVLDSSQGNTIYQIAFIKWVKSTYPHLEVVAGNVVTQD 304
Query: 303 QAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLR 362
QAKNLIDAGAD +RIGMGSGSICITQEVLACGRPQ TA+YKVA+Y ASRGVPC ADGGLR
Sbjct: 305 QAKNLIDAGADGIRIGMGSGSICITQEVLACGRPQGTAVYKVAQYCASRGVPCTADGGLR 364
Query: 363 NVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGK 422
VGD+CKALA+GAN AMLG M++GT+ETPGEYFFK G+RLK YRGMGS++AM QG+ESGK
Sbjct: 365 QVGDICKALAIGANCAMLGGMLSGTTETPGEYFFKGGVRLKVYRGMGSLEAMNQGKESGK 424
Query: 423 RYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQV 482
RYLSENE +QVAQGV+G+V+DKGS KL+AY+ KGLQQSAQDIGE+SFDAIREK+Y GQV
Sbjct: 425 RYLSENEAVQVAQGVSGSVVDKGSAAKLIAYVSKGLQQSAQDIGEISFDAIREKMYAGQV 484
Query: 483 LFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
LF+RR+ TAQ EG VHSLH YE+KLFA+K+
Sbjct: 485 LFSRRSPTAQGEGGVHSLHSYEKKLFAAKM 514
>gi|154336078|ref|XP_001564275.1| inosine-5'-monophosphate dehydrogenase [Leishmania braziliensis
MHOM/BR/75/M2904]
gi|134061309|emb|CAM38334.1| inosine-5'-monophosphate dehydrogenase [Leishmania braziliensis]
Length = 514
Score = 804 bits (2076), Expect = 0.0, Method: Composition-based stats.
Identities = 386/510 (75%), Positives = 447/510 (87%)
Query: 3 NTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLV 62
N N R K ++DG TAEELF DGL++NDFIILPGFIDF ++ VN+SGQFTK I LH+P+V
Sbjct: 5 NANYRIKVIKDGCTAEELFQGDGLTYNDFIILPGFIDFGAADVNISGQFTKQIRLHIPIV 64
Query: 63 SSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVP 122
SSPMDT+TE+ MA+ MALMGG+GV+HNNCTVE+Q MV+SVK YRNGFI KPKSV+P+ P
Sbjct: 65 SSPMDTITENEMAKTMALMGGVGVLHNNCTVERQVEMVKSVKAYRNGFISKPKSVTPNTP 124
Query: 123 VSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVE 182
+S I IK KGISGILVTE G GKLLGIVCTKDID+VK PVS MTRR+ MTVE
Sbjct: 125 ISEIIRIKEGKGISGILVTENGDPHGKLLGIVCTKDIDYVKKKETPVSAVMTRRDKMTVE 184
Query: 183 RYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAA 242
R PI+LEEAMDVLNRSRHGYLP++N DE+V LCSRRDAVRARDYP+S+LD++G L+CAA
Sbjct: 185 RAPIQLEEAMDVLNRSRHGYLPIVNGNDEIVYLCSRRDAVRARDYPHSTLDKSGRLICAA 244
Query: 243 ATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQD 302
ATSTR DK RVAAL+E G+DVLVLDSSQGNTIYQ++FI+W+K TYPHLEVVAGNVVTQD
Sbjct: 245 ATSTRPEDKRRVAALAEVGVDVLVLDSSQGNTIYQIAFIKWIKSTYPHLEVVAGNVVTQD 304
Query: 303 QAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLR 362
QAKNLIDAGAD +RIGMGSGSICITQEVLACGRPQ TA++KVA+Y ASRGVPC ADGGLR
Sbjct: 305 QAKNLIDAGADGIRIGMGSGSICITQEVLACGRPQGTAVFKVAQYCASRGVPCTADGGLR 364
Query: 363 NVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGK 422
VGD+CKALA+GAN AMLG M++GT+ETPGEYFFK G+RLK YRGMGS++AM QG+ESGK
Sbjct: 365 QVGDICKALAIGANCAMLGGMLSGTTETPGEYFFKGGVRLKVYRGMGSLEAMSQGKESGK 424
Query: 423 RYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQV 482
RYLSENE +QVAQGV+G V+DKGS KL+AYI KGLQQSAQDIGE+SFDAIREK+Y GQV
Sbjct: 425 RYLSENEVVQVAQGVSGNVVDKGSAEKLIAYIAKGLQQSAQDIGEISFDAIREKLYAGQV 484
Query: 483 LFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
LF+RR++TAQ EG VHSLH YE+KLFA+K+
Sbjct: 485 LFSRRSVTAQGEGGVHSLHSYEKKLFAAKM 514
>gi|56207809|emb|CAI21140.1| novel protein similar to vertebrate IMP (inosine monophosphate)
dehydrogenase 1 (IMPDH1) [Danio rerio]
Length = 539
Score = 561 bits (1446), Expect = e-158, Method: Composition-based stats.
Identities = 277/503 (55%), Positives = 370/503 (73%), Gaps = 3/503 (0%)
Query: 9 KTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMD 67
+++RDG TAEELFS+ DG+++NDF+ILPGFIDF S +V+++ TK I L PL+SSPMD
Sbjct: 37 QSVRDGHTAEELFSKGDGMTYNDFLILPGFIDFTSDEVDLTSALTKKITLKTPLISSPMD 96
Query: 68 TVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIR 127
TVTESSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V +
Sbjct: 97 TVTESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKRFEQGFITDPVVLSPHHTVGDVL 156
Query: 128 NIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYP 185
K G SGI +TE GK KL+GIV ++DIDF+ KD + + + MT+RE++ V
Sbjct: 157 EAKVRHGFSGIPITETGKMGSKLVGIVTSRDIDFLSEKDNNKYLEEAMTKREDLVVAPAG 216
Query: 186 IKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATS 245
+ L+EA D+L RS+ G LP++NDKDE+V + +R D + RDYP +S D LLC AA
Sbjct: 217 VTLKEANDILQRSKKGKLPIVNDKDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIG 276
Query: 246 TREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAK 305
TRE DK R+ L+++G+D++VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAK
Sbjct: 277 TREDDKYRLDLLTQSGVDMVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAK 336
Query: 306 NLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVG 365
NLIDAG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG
Sbjct: 337 NLIDAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVG 396
Query: 366 DVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYL 425
V KAL++GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY
Sbjct: 397 HVVKALSLGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNTSSQKRYF 456
Query: 426 SENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFN 485
SE + ++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F
Sbjct: 457 SEGDKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSVLRSMMYSGELKFE 516
Query: 486 RRTLTAQSEGAVHSLHHYERKLF 508
+RT++AQ EG VH LH +E++L+
Sbjct: 517 KRTMSAQVEGGVHGLHSFEKRLY 539
>gi|94732689|emb|CAK04261.1| novel protein similar to vertebrate IMP (inosine monophosphate)
dehydrogenase 1 (IMPDH1) [Danio rerio]
Length = 534
Score = 557 bits (1436), Expect = e-157, Method: Composition-based stats.
Identities = 278/499 (55%), Positives = 363/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF S +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 36 DGLTAQQLFAIGDGLTYNDFLILPGFIDFISDEVDLTSALTRKITLKTPLISSPMDTVTE 95
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
SSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 96 SSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSPRHTVGDVFEAKV 155
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI VTE GK KL+GIV ++DIDF+ KD P+ + MT+RE++ V + L+
Sbjct: 156 RHGFSGIPVTETGKMGSKLVGIVTSRDIDFLSEKDYDRPLEESMTKREDLVVAPAGVTLK 215
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA D+L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 216 EANDILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGTRED 275
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+DV+VLDSSQGN+++Q+S I ++K+ YP L+VV GNVVT QAKNLID
Sbjct: 276 DKYRLDLLMQAGVDVIVLDSSQGNSVFQISMINYIKQKYPELQVVGGNVVTAAQAKNLID 335
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG V K
Sbjct: 336 AGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVK 395
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 396 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNNSSQKRYFSEGD 455
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 456 KVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKFEKRTM 515
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 516 SAQVEGGVHGLHSYEKRLY 534
>gi|148222892|ref|NP_001082410.1| similar to inosine 5'-phosphate dehydrogenase 2 [Xenopus laevis]
gi|27769229|gb|AAH42315.1| MGC53627 protein [Xenopus laevis]
Length = 514
Score = 556 bits (1433), Expect = e-156, Method: Composition-based stats.
Identities = 277/499 (55%), Positives = 365/499 (73%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF + DGL++NDF+ILPG+IDF + +V+++ TK I L P+VSSPMDTVTE
Sbjct: 16 DGLTAQQLFGAGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPMVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
++MA AMAL GGIGVIH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 ANMAIAMALTGGIGVIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKHCVRHVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVK--DASAPVSQYMTRRENMTVERYPIKLE 189
G GI +TE GK KL GI+ ++DIDF+K D +S+ MTRRE++ V + L+
Sbjct: 136 RHGFCGIPITENGKMGSKLAGIISSRDIDFLKAEDHDLALSEIMTRREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N DE+V + +R D + RDYP +S D LLC AAT T E
Sbjct: 196 EANEILQRSKKGKLPIVNGDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAATGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+D +VLDSSQGN+I+Q++ I+++K+ YP L+V+AGNVVT QAKNLID
Sbjct: 256 DKYRLDLLVQAGVDAVVLDSSQGNSIFQINMIKYIKEKYPDLQVIAGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AGAD+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNVSSQKRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT+
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFIPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++LF
Sbjct: 496 SAQVEGGVHGLHSYEKRLF 514
>gi|119891311|ref|XP_001252299.1| PREDICTED: inosine monophosphate dehydrogenase 1 [Bos taurus]
Length = 660
Score = 553 bits (1425), Expect = e-155, Method: Composition-based stats.
Identities = 269/499 (53%), Positives = 360/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 162 DGLTAQQLFANADGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVTE 221
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 222 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKI 281
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 282 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRNELVVAPAGVTLK 341
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 342 EANEILQRSKKGKLPIVNDRDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRED 401
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 402 DKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 461
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 462 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVK 521
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 522 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 581
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 582 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 641
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 642 SAQIEGGVHGLHSYEKRLY 660
>gi|50345008|ref|NP_001002177.1| hypothetical protein LOC431724 [Danio rerio]
gi|49256673|gb|AAH74090.1| Zgc:91911 [Danio rerio]
gi|148725646|emb|CAN87720.1| novel protein (zgc:91911) [Danio rerio]
Length = 544
Score = 553 bits (1425), Expect = e-155, Method: Composition-based stats.
Identities = 276/494 (55%), Positives = 358/494 (72%), Gaps = 3/494 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF S +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 16 DGLTAQQLFAIGDGLTYNDFLILPGFIDFISDEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
SSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 76 SSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSPRHTVGDVFEAKV 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI VTE GK KL+GIV ++DIDF+ KD P+ + MT+RE++ V + L+
Sbjct: 136 RHGFSGIPVTETGKMGSKLVGIVTSRDIDFLSEKDYDRPLEESMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA D+L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANDILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+DV+VLDSSQGN+++Q+S I ++K+ YP L+VV GNVVT QAKNLID
Sbjct: 256 DKYRLDLLMQAGVDVIVLDSSQGNSVFQISMINYIKQKYPELQVVGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNNSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 436 KVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHY 503
+AQ EG VH LH Y
Sbjct: 496 SAQVEGGVHGLHSY 509
>gi|62122931|ref|NP_001014391.1| hypothetical protein LOC338306 [Danio rerio]
gi|56207808|emb|CAI21139.1| novel protein similar to vertebrate IMP (inosine monophosphate)
dehydrogenase 1 (IMPDH1) [Danio rerio]
gi|61403149|gb|AAH91790.1| Si:dkey-31f5.7 [Danio rerio]
Length = 514
Score = 553 bits (1425), Expect = e-155, Method: Composition-based stats.
Identities = 273/499 (54%), Positives = 365/499 (73%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG +A++LF+ DGL++NDF+ILPGFIDF S +V+++ TK I L PL+SSPMDTVTE
Sbjct: 16 DGLSAQQLFAVGDGLTYNDFLILPGFIDFTSDEVDLTSALTKKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
SSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 76 SSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKRFEQGFITDPVVLSPHHTVGDVLEAKV 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE GK KL+GIV ++DIDF+ KD + + + MT+RE++ V + L+
Sbjct: 136 RHGFSGIPITETGKMGSKLVGIVTSRDIDFLSEKDNNKYLEEAMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA D+L RS+ G LP++NDKDE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANDILQRSKKGKLPIVNDKDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L+++G+D++VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQSGVDMVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
AL++GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALSLGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNTSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 436 KVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSVLRSMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH +E++L+
Sbjct: 496 SAQVEGGVHGLHSFEKRLY 514
>gi|71895387|ref|NP_001025772.1| inosine monophosphate dehydrogenase 2 [Gallus gallus]
gi|60098399|emb|CAH65030.1| hypothetical protein [Gallus gallus]
Length = 514
Score = 552 bits (1423), Expect = e-155, Method: Composition-based stats.
Identities = 272/499 (54%), Positives = 364/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LFS DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFSCGDGLTYNDFLILPGYIDFTADQVDLTSALTKRITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP+ V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPNDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDAS--APVSQYMTRRENMTVERYPIKLE 189
G GI +T+ GK GKL+GI+ ++DIDF+K++ P+ + MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDNGKMGGKLVGIISSRDIDFLKESEHDLPLGEIMTKREDLVVAPSGVMLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDSKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+D +VLDSSQGN+I+Q++ I+++K+ YP+L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLVQAGVDAVVLDSSQGNSIFQINMIKYIKEKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNLGSQNRYFSETD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFIPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTT 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++LF
Sbjct: 496 SAQVEGGVHGLHSYEKRLF 514
>gi|118150800|ref|NP_001071309.1| inosine monophosphate dehydrogenase 1 [Bos taurus]
gi|117306245|gb|AAI26585.1| IMP (inosine monophosphate) dehydrogenase 1 [Bos taurus]
Length = 571
Score = 550 bits (1418), Expect = e-155, Method: Composition-based stats.
Identities = 269/499 (53%), Positives = 360/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 73 DGLTAQQLFANADGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVTE 132
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 133 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKI 192
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 193 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRNELVVAPAGVTLK 252
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 253 EANEILQRSKKGKLPIVNDRDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRED 312
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 313 DKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 372
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 373 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVK 432
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 433 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 492
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 493 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 552
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 553 SAQIEGGVHGLHSYEKRLY 571
>gi|34328928|ref|NP_899066.1| inosine monophosphate dehydrogenase 1 isoform b [Homo sapiens]
gi|51095068|gb|EAL24311.1| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
gi|54673520|gb|AAH33622.2| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
Length = 563
Score = 549 bits (1415), Expect = e-154, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 359/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 65 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 124
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 125 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 184
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 185 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 244
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 245 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 304
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 305 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 364
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 365 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 424
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 425 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 484
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 485 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 544
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 545 SAQIEGGVHGLHSYEKRLY 563
>gi|62859741|ref|NP_001017283.1| IMP (inosine monophosphate) dehydrogenase 1 [Xenopus tropicalis]
gi|89270400|emb|CAJ83974.1| IMP (inosine monophosphate) dehydrogenase 1 [Xenopus tropicalis]
Length = 514
Score = 549 bits (1415), Expect = e-154, Method: Composition-based stats.
Identities = 273/499 (54%), Positives = 362/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA+ LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 16 DGLTAQHLFANSDGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
S MA AMALMGGIG+IH+NCT E QA VR VK + GFI P +S + V + K+
Sbjct: 76 SDMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSLNHTVGDVFEAKN 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI VTE GK KL+GIV ++DIDF+ KD S +S+ MT+R+ + V + L+
Sbjct: 136 RHGFSGIPVTETGKMGSKLVGIVTSRDIDFLTEKDYSTYLSEVMTKRDELVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDCRKQLLCGAAIGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQAGVDVVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDALRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNTSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ +RT+
Sbjct: 436 KVKVAQGVSGSIQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKLEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 496 SAQVEGGVHGLHSYEKRLY 514
>gi|156616279|ref|NP_001096075.1| inosine monophosphate dehydrogenase 1 isoform c [Homo sapiens]
Length = 589
Score = 548 bits (1413), Expect = e-154, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 359/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 91 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 150
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 151 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 210
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 211 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 270
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 271 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 330
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 331 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 390
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 391 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 450
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 451 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 510
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 511 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 570
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 571 SAQIEGGVHGLHSYEKRLY 589
>gi|25014074|sp|P20839|IMDH1_HUMAN Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1)
(IMPDH-I) (IMPD 1)
Length = 514
Score = 548 bits (1413), Expect = e-154, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 359/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 16 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 76 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 136 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 436 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 496 SAQIEGGVHGLHSYEKRLY 514
>gi|34328930|ref|NP_000874.2| inosine monophosphate dehydrogenase 1 isoform a [Homo sapiens]
gi|51095067|gb|EAL24310.1| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
Length = 599
Score = 548 bits (1413), Expect = e-154, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 359/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 101 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 160
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 161 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 220
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 221 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 280
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 281 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 340
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 341 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 400
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 401 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 460
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 461 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 520
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 521 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 580
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 581 SAQIEGGVHGLHSYEKRLY 599
>gi|119585350|gb|EAW64946.1| hCG2002013, isoform CRA_a [Homo sapiens]
Length = 584
Score = 548 bits (1412), Expect = e-154, Method: Composition-based stats.
Identities = 271/499 (54%), Positives = 363/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 86 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 145
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 146 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 205
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V I L+
Sbjct: 206 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLK 265
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 266 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 325
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K YP+L+V+ GNVVT QAKNLID
Sbjct: 326 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 385
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 386 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 445
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 446 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 505
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 506 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 565
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 566 SAQVEGGVHSLHSYEKRLF 584
>gi|307066|gb|AAA36112.1| inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)
Length = 514
Score = 548 bits (1412), Expect = e-154, Method: Composition-based stats.
Identities = 271/499 (54%), Positives = 363/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V I L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPRSITLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K YP+L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>gi|147904959|ref|NP_001080792.1| inosine 5'-phosphate dehydrogenase 1 [Xenopus laevis]
gi|28422466|gb|AAH46868.1| Impdh1-prov protein [Xenopus laevis]
Length = 514
Score = 548 bits (1411), Expect = e-154, Method: Composition-based stats.
Identities = 273/499 (54%), Positives = 363/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ +GL++NDF+ILPGFIDF + +V+++ T+ I L P++SSPMDTVTE
Sbjct: 16 DGLTAQQLFANSEGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPMISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
S MA AMALMGGIG+IH+NCT E QA VR VK + GFI P +S + V + K+
Sbjct: 76 SDMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSLNHTVGDVFEAKN 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI VTE GK KL+GIV ++DIDF+ KD S +S+ MT+RE++ V + L+
Sbjct: 136 RHGFSGIPVTETGKMGSKLVGIVTSRDIDFLTEKDYSTYLSEVMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDCRKQLLCGAAIGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+DV+VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAKNLID
Sbjct: 256 DKYRLDLLMQAGVDVVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP VADGG++ VG V K
Sbjct: 316 AGVDALRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVVADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSTSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ +RT+
Sbjct: 436 KVKVAQGVSGSIQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKLEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 496 SAQVEGGVHGLHSYEKRLY 514
>gi|119604058|gb|EAW83652.1| IMP (inosine monophosphate) dehydrogenase 1, isoform CRA_d [Homo
sapiens]
Length = 522
Score = 548 bits (1411), Expect = e-154, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 359/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 24 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 83
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 84 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 143
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 144 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 203
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 204 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 263
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 264 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 323
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 324 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 383
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 384 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 443
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 444 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 503
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 504 SAQIEGGVHGLHSYEKRLY 522