BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= AAX70181.1__[Trypanosoma_brucei]
         (1142 letters)

Database: nr.pal 
           6,348,806 sequences; 2,166,943,470 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|72388944|ref|XP_844767.1|  NADH-dependent fumarate reduct...  2150   0.0  
gi|23928423|gb|AAN40014.1|AF457132_1  NADH-dependent fumarat...  2143   0.0  
gi|60460038|gb|AAX20163.1|  mitochondrial NADH-dependent fum...  2139   0.0  
gi|71400421|ref|XP_803046.1|  NADH-dependent fumarate reduct...  1597   0.0  
gi|72547417|ref|XP_843225.1|  NADH-dependent fumarate reduct...  1379   0.0  
gi|146100731|ref|XP_001468931.1|  NADH-dependent fumarate re...  1375   0.0  
gi|154344555|ref|XP_001568219.1|  NADH-dependent fumarate re...  1366   0.0  
gi|71410008|ref|XP_807320.1|  NADH-dependent fumarate reduct...  1308   0.0  
gi|71747118|ref|XP_822614.1|  NADH-dependent fumarate reduct...  1250   0.0  
gi|60460036|gb|AAX20162.1|  mitochondrial NADH-dependent fum...  1247   0.0  
gi|72547207|ref|XP_843192.1|  NADH-dependent fumarate reduct...  1240   0.0  
gi|146100590|ref|XP_001468899.1|  NADH-dependent fumarate re...  1221   0.0  
gi|154344505|ref|XP_001568194.1|  NADH-dependent fumarate re...  1202   0.0  
gi|72388946|ref|XP_844768.1|  NADH-dependent fumarate reduct...   998   0.0  
gi|60460039|gb|AAX20164.1|  mitochondrial NADH-dependent fum...   992   0.0  
gi|71416397|ref|XP_810232.1|  NADH-dependent fumarate reduct...   824   0.0  
gi|71403387|ref|XP_804499.1|  NADH-dependent fumarate reduct...   758   0.0  
gi|71416399|ref|XP_810233.1|  NADH-dependent fumarate reduct...   725   0.0  
gi|154344557|ref|XP_001568220.1|  NADH-dependent fumarate re...   548   e-154
gi|72547421|ref|XP_843226.1|  NADH-dependent fumarate reduct...   540   e-151
gi|146100735|ref|XP_001468932.1|  NADH-dependent fumarate re...   532   e-149
gi|154344559|ref|XP_001568221.1|  NADH-dependent fumarate re...   514   e-143
gi|71419607|ref|XP_811221.1|  NADH-dependent fumarate reduct...   438   e-120
gi|71986328|ref|NP_498164.3|  F48E8.3 [Caenorhabditis elegan...   312   1e-82
gi|170573380|ref|XP_001892448.1|  Hypothetical FAD-dependent...   299   8e-79
gi|71021775|ref|XP_761118.1|  hypothetical protein UM04971.1...   294   2e-77
gi|157773609|ref|XP_001664870.1|  hypothetical protein CBG05...   291   2e-76
gi|85119766|ref|XP_965711.1|  hypothetical protein NCU02580 ...   278   1e-72
gi|39943078|ref|XP_361076.1|  conserved hypothetical protein...   274   3e-71
gi|58259717|ref|XP_567271.1|  fumarate reductase (NADH) [Cry...   273   5e-71
gi|67522172|ref|XP_659147.1|  hypothetical protein AN1543.2 ...   271   2e-70
gi|46135637|ref|XP_389517.1|  hypothetical protein FG09341.1...   270   4e-70
gi|119180100|ref|XP_001241557.1|  hypothetical protein CIMG_...   270   4e-70
gi|115401552|ref|XP_001216364.1|  hypothetical protein ATEG_...   268   2e-69
gi|70983656|ref|XP_747355.1|  fumarate reductase Osm1 [Asper...   266   7e-69
gi|169603405|ref|XP_001795124.1|  hypothetical protein SNOG_...   266   7e-69
gi|134116776|ref|XP_773060.1|  hypothetical protein CNBJ3360...   265   2e-68
gi|156054748|ref|XP_001593300.1|  hypothetical protein SS1G_...   265   2e-68
gi|119484630|ref|XP_001262094.1|  fumarate reductase Osm1, p...   265   2e-68
gi|116181512|ref|XP_001220605.1|  conserved hypothetical pro...   264   4e-68
gi|121719922|ref|XP_001276659.1|  fumarate reductase Osm1, p...   263   4e-68
gi|169766332|ref|XP_001817637.1|  [Aspergillus oryzae] >gi|8...   263   6e-68
gi|169847377|ref|XP_001830400.1|  hypothetical protein CC1G_...   262   1e-67
gi|145253004|ref|XP_001398015.1|  hypothetical protein An16g...   261   3e-67
gi|146413216|ref|XP_001482579.1|  hypothetical protein PGUG_...   259   9e-67
gi|170097978|ref|XP_001880208.1|  fumarate reductase [Laccar...   259   1e-66
gi|167525839|ref|XP_001747254.1|  predicted protein [Monosig...   257   4e-66
gi|149239496|ref|XP_001525624.1|  hypothetical protein LELG_...   256   6e-66
gi|68467323|ref|XP_722323.1|  hypothetical protein CaO19_124...   256   8e-66
gi|167521137|ref|XP_001744907.1|  predicted protein [Monosig...   254   2e-65
gi|50420341|ref|XP_458704.1|  hypothetical protein DEHA0D062...   248   2e-63
gi|19115151|ref|NP_594239.1|  fumerate reductase [Schizosacc...   248   3e-63
gi|145353596|ref|XP_001421094.1|  predicted protein [Ostreoc...   244   4e-62
gi|45198885|ref|NP_985914.1|  AFR367Wp [Ashbya gossypii ATCC...   242   2e-61
gi|58337211|ref|YP_193796.1|  fumarate reductase flavoprotei...   241   2e-61
gi|149388941|gb|EAZ62928.2|  Osmotic growth protein [Pichia ...   241   3e-61
gi|116061092|emb|CAL56480.1|  Cytochrome b5 (ISS) [Ostreococ...   240   5e-61
gi|50311613|ref|XP_455832.1|  unnamed protein product [Kluyv...   239   6e-61
gi|126276120|ref|XP_001386951.1|  Osmotic growth protein [Pi...   239   1e-60
gi|161507394|ref|YP_001577348.1|  fumarate reductase [Lactob...   238   2e-60
gi|154289525|ref|XP_001545378.1|  fumarate reductase flavopr...   236   6e-60
gi|157864558|ref|XP_001680989.1|  flavoprotein subunit-like ...   234   4e-59
gi|156837217|ref|XP_001642640.1|  hypothetical protein Kpol_...   233   8e-59
gi|154280827|ref|XP_001541226.1|  hypothetical protein HCAG_...   230   5e-58
gi|6322511|ref|NP_012585.1|  Fumarate reductase, catalyzes t...   226   6e-57
gi|27764314|emb|CAD60594.1|  unnamed protein product [Podosp...   226   8e-57
gi|151944665|gb|EDN62924.1|  conserved protein [Saccharomyce...   226   1e-56
gi|6320788|ref|NP_010867.1|  Soluble fumarate reductase, req...   225   2e-56
gi|145352970|ref|XP_001420806.1|  predicted protein [Ostreoc...   225   2e-56
gi|156841614|ref|XP_001644179.1|  hypothetical protein Kpol_...   224   3e-56
gi|50292783|ref|XP_448824.1|  unnamed protein product [Candi...   224   4e-56
gi|50289761|ref|XP_447312.1|  hypothetical protein CAGL0I013...   219   1e-54
gi|109646208|ref|ZP_01370128.1|  flavocytochrome c [Desulfit...   217   3e-54
gi|89895885|ref|YP_519372.1|  putative fumarate reductase fl...   217   5e-54
gi|28377901|ref|NP_784793.1|  fumarate reductase, flavoprote...   215   1e-53
gi|90962298|ref|YP_536214.1|  Fumarate reductase flavoprotei...   215   1e-53
gi|68486579|ref|XP_712840.1|  fumarate reductase [Candida al...   215   2e-53
gi|85094033|ref|XP_959805.1|  hypothetical protein NCU06042 ...   215   2e-53
gi|145605521|ref|XP_364381.2|  hypothetical protein MGG_0922...   215   2e-53
gi|115402435|ref|XP_001217294.1|  hypothetical protein ATEG_...   214   3e-53
gi|121711455|ref|XP_001273343.1|  FAD dependent oxidoreducta...   214   5e-53
gi|159123228|gb|EDP48348.1|  FAD dependent oxidoreductase, p...   213   7e-53
gi|149248222|ref|XP_001528498.1|  conserved hypothetical pro...   213   8e-53
gi|118745073|ref|ZP_01593055.1|  flavocytochrome c [Geobacte...   212   1e-52
gi|119482826|ref|XP_001261441.1|  FAD dependent oxidoreducta...   211   2e-52
gi|116492121|ref|YP_803856.1|  Succinate dehydrogenase/fumar...   211   2e-52
gi|146322001|ref|YP_001201712.1|  fumarate reductase flavopr...   210   4e-52
gi|19703402|ref|NP_602964.1|  Fumarate reductase flavoprotei...   210   6e-52
gi|70987038|ref|XP_749003.1|  FAD dependent oxidoreductase [...   210   6e-52
gi|146142507|gb|ABQ01723.1|  fumarate reductase flavoprotein...   209   1e-51
gi|170017992|ref|YP_001728911.1|  Succinate dehydrogenase/fu...   209   1e-51
gi|167006720|ref|ZP_02272194.1|  Fumarate reductase flavopro...   209   1e-51
gi|92089370|ref|ZP_01274316.1|  Flavocytochrome c [Lactobaci...   208   2e-51
gi|116060798|emb|CAL57276.1|  Cytochrome b5 (ISS) [Ostreococ...   208   2e-51
gi|145236557|ref|XP_001390926.1|  hypothetical protein An06g...   208   2e-51
gi|67523803|ref|XP_659961.1|  hypothetical protein AN2357.2 ...   208   2e-51
gi|150865240|ref|XP_001384376.2|  fumarate reductase flavopr...   208   2e-51
gi|145618385|ref|ZP_01774444.1|  flavocytochrome c [Geobacte...   207   4e-51
gi|148544742|ref|YP_001272112.1|  flavocytochrome c [Lactoba...   207   4e-51
gi|42519274|ref|NP_965204.1|  fumarate reductase flavoprotei...   206   7e-51

>gi|72388944|ref|XP_844767.1| NADH-dependent fumarate reductase [Trypanosoma brucei TREU927]
 gi|62176060|gb|AAX70181.1| NADH-dependent fumarate reductase [Trypanosoma brucei]
 gi|70801301|gb|AAZ11208.1| NADH-dependent fumarate reductase [Trypanosoma brucei]
          Length = 1142

 Score = 2150 bits (5570), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1059/1142 (92%), Positives = 1059/1142 (92%)

Query: 1    MVDGRSSASIXXXXXXXXXXXXXXXXXXLLQDSPLHTTMQYATSGLELTVPYALKVVASA 60
            MVDGRSSASI                  LLQDSPLHTTMQYATSGLELTVPYALKVVASA
Sbjct: 1    MVDGRSSASIVAVDPERAARERDAAARALLQDSPLHTTMQYATSGLELTVPYALKVVASA 60

Query: 61   DTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVMACCQ 120
            DTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVMACCQ
Sbjct: 61   DTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVMACCQ 120

Query: 121  RVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQACTLPNSFVIDFEAGTISRK 180
            RVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQACTLPNSFVIDFEAGTISRK
Sbjct: 121  RVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQACTLPNSFVIDFEAGTISRK 180

Query: 181  HEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVGITRPP 240
            HEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVGITRPP
Sbjct: 181  HEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVGITRPP 240

Query: 241  SLDMLRNPPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKAKELMKPSQS 300
            SLDMLRNPPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKAKELMKPSQS
Sbjct: 241  SLDMLRNPPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKAKELMKPSQS 300

Query: 301  NIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWXXXXXXXXXXXXXXXENERVAK 360
            NIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGW               ENERVAK
Sbjct: 301  NIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWRYVRDTVRDYRVYVRENERVAK 360

Query: 361  MFEIATEDAEMRKRRISNTLPARVIVVXXXXXXXXXXXXXXXCGAQVVLMEKEAKLGGNS 420
            MFEIATEDAEMRKRRISNTLPARVIVV               CGAQVVLMEKEAKLGGNS
Sbjct: 361  MFEIATEDAEMRKRRISNTLPARVIVVGGGLAGLSAAIEAAGCGAQVVLMEKEAKLGGNS 420

Query: 421  AKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLT 480
            AKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLT
Sbjct: 421  AKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLT 480

Query: 481  SLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENC 540
            SLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENC
Sbjct: 481  SLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENC 540

Query: 541  SVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLRE 600
            SVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLRE
Sbjct: 541  SVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLRE 600

Query: 601  HAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPE 660
            HAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPE
Sbjct: 601  HAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPE 660

Query: 661  ALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFG 720
            ALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFG
Sbjct: 661  ALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFG 720

Query: 721  VSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYP 780
            VSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYP
Sbjct: 721  VSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYP 780

Query: 781  CVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXX 840
            CVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLF      
Sbjct: 781  CVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFGAGEVT 840

Query: 841  XXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGA 900
                       NSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGA
Sbjct: 841  GGVHGGNRLGGNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGA 900

Query: 901  GSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKG 960
            GSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKG
Sbjct: 901  GSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKG 960

Query: 961  TLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQII 1020
            TLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQII
Sbjct: 961  TLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQII 1020

Query: 1021 KAAFMKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXGKFKKTFVLNRPPPLWTDG 1080
            KAAFMKPFIDTLESVHLIYAAED                  GKFKKTFVLNRPPPLWTDG
Sbjct: 1021 KAAFMKPFIDTLESVHLIYAAEDVTELTYREVLEERRRESRGKFKKTFVLNRPPPLWTDG 1080

Query: 1081 VGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDETEPSGSS 1140
            VGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDETEPSGSS
Sbjct: 1081 VGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDETEPSGSS 1140

Query: 1141 KI 1142
            KI
Sbjct: 1141 KI 1142



>gi|23928423|gb|AAN40014.1|AF457132_1 NADH-dependent fumarate reductase [Trypanosoma brucei]
          Length = 1142

 Score = 2143 bits (5552), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1056/1142 (92%), Positives = 1056/1142 (92%)

Query: 1    MVDGRSSASIXXXXXXXXXXXXXXXXXXLLQDSPLHTTMQYATSGLELTVPYALKVVASA 60
            MVDGRSSASI                  LLQDSPLHTTMQYATSGLELTVPYALKVVASA
Sbjct: 1    MVDGRSSASIVAVDPERAARERDAAARALLQDSPLHTTMQYATSGLELTVPYALKVVASA 60

Query: 61   DTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVMACCQ 120
            DTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVMACCQ
Sbjct: 61   DTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVMACCQ 120

Query: 121  RVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQACTLPNSFVIDFEAGTISRK 180
            RVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQACTLPNSFVIDFEAGTISRK
Sbjct: 121  RVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQACTLPNSFVIDFEAGTISRK 180

Query: 181  HEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVGITRPP 240
            HEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVGITRPP
Sbjct: 181  HEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVGITRPP 240

Query: 241  SLDMLRNPPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKAKELMKPSQS 300
            SLDML NPPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWK KELMKPSQS
Sbjct: 241  SLDMLPNPPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKGKELMKPSQS 300

Query: 301  NIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWXXXXXXXXXXXXXXXENERVAK 360
            NIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGW               ENERVAK
Sbjct: 301  NIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWRYVRDTVRDYRVYVRENERVAK 360

Query: 361  MFEIATEDAEMRKRRISNTLPARVIVVXXXXXXXXXXXXXXXCGAQVVLMEKEAKLGGNS 420
            MFEIATEDAEMRKRRISNTLPARVIVV               CGAQVVLMEKEAKLGGNS
Sbjct: 361  MFEIATEDAEMRKRRISNTLPARVIVVGGGLAGLSAAIEAAGCGAQVVLMEKEAKLGGNS 420

Query: 421  AKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLT 480
            AKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLT
Sbjct: 421  AKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLT 480

Query: 481  SLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENC 540
            SLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENC
Sbjct: 481  SLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENC 540

Query: 541  SVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLRE 600
            SVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLRE
Sbjct: 541  SVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLRE 600

Query: 601  HAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPE 660
            HAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPE
Sbjct: 601  HAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPE 660

Query: 661  ALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFG 720
            ALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFG
Sbjct: 661  ALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFG 720

Query: 721  VSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYP 780
            VSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLS SQRSCPITRKSVYP
Sbjct: 721  VSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSISQRSCPITRKSVYP 780

Query: 781  CVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXX 840
            CVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLF      
Sbjct: 781  CVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFGAGEVT 840

Query: 841  XXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGA 900
                       NSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGA
Sbjct: 841  GGVHGGNRLGGNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGA 900

Query: 901  GSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKG 960
            GSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKG
Sbjct: 901  GSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKG 960

Query: 961  TLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQII 1020
            TLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQII
Sbjct: 961  TLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQII 1020

Query: 1021 KAAFMKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXGKFKKTFVLNRPPPLWTDG 1080
            KAAFMKPFIDTLESVHLIYAAED                  GKFKKTFVLNRPPPLWTDG
Sbjct: 1021 KAAFMKPFIDTLESVHLIYAAEDVTELTYREVLEERRRESRGKFKKTFVLNRPPPLWTDG 1080

Query: 1081 VGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDETEPSGSS 1140
            VGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDETEPSGSS
Sbjct: 1081 VGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDETEPSGSS 1140

Query: 1141 KI 1142
            KI
Sbjct: 1141 KI 1142



>gi|60460038|gb|AAX20163.1| mitochondrial NADH-dependent fumarate reductase [Trypanosoma brucei]
          Length = 1142

 Score = 2139 bits (5542), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1055/1142 (92%), Positives = 1055/1142 (92%)

Query: 1    MVDGRSSASIXXXXXXXXXXXXXXXXXXLLQDSPLHTTMQYATSGLELTVPYALKVVASA 60
            MVDGRSSASI                  LLQDSPLHTTMQYATSGLELTVPYALKVVASA
Sbjct: 1    MVDGRSSASIVAVDPERAARERDAAARALLQDSPLHTTMQYATSGLELTVPYALKVVASA 60

Query: 61   DTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVMACCQ 120
            DTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVMACCQ
Sbjct: 61   DTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVMACCQ 120

Query: 121  RVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQACTLPNSFVIDFEAGTISRK 180
            RVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQACTLPNSFVIDFEAGTISRK
Sbjct: 121  RVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQACTLPNSFVIDFEAGTISRK 180

Query: 181  HEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVGITRPP 240
            HEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVGITRPP
Sbjct: 181  HEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVGITRPP 240

Query: 241  SLDMLRNPPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKAKELMKPSQS 300
            SLDML NPPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWK KELMKPSQS
Sbjct: 241  SLDMLPNPPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKGKELMKPSQS 300

Query: 301  NIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWXXXXXXXXXXXXXXXENERVAK 360
            NIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGW               ENERVAK
Sbjct: 301  NIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWRYVRDTVRDYRVYVRENERVAK 360

Query: 361  MFEIATEDAEMRKRRISNTLPARVIVVXXXXXXXXXXXXXXXCGAQVVLMEKEAKLGGNS 420
            MFEIATEDAEMRKRRISNTLPARVIVV               CGAQVVLMEKEAKLGGNS
Sbjct: 361  MFEIATEDAEMRKRRISNTLPARVIVVGGGLAGLSAAIEAAGCGAQVVLMEKEAKLGGNS 420

Query: 421  AKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLT 480
            AKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLT
Sbjct: 421  AKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLT 480

Query: 481  SLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENC 540
            SLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLE HVRGNLSGRITIMENC
Sbjct: 481  SLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEGHVRGNLSGRITIMENC 540

Query: 541  SVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLRE 600
            SVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLRE
Sbjct: 541  SVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLRE 600

Query: 601  HAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPE 660
            HAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPE
Sbjct: 601  HAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPE 660

Query: 661  ALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFG 720
            ALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFG
Sbjct: 661  ALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFG 720

Query: 721  VSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYP 780
            VSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLS SQRSCPITRKSVYP
Sbjct: 721  VSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSISQRSCPITRKSVYP 780

Query: 781  CVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXX 840
            CVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLF      
Sbjct: 781  CVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFGAGEVT 840

Query: 841  XXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGA 900
                       NSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGA
Sbjct: 841  GGVHGGNRLGGNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGA 900

Query: 901  GSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKG 960
            GSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKG
Sbjct: 901  GSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKG 960

Query: 961  TLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQII 1020
            TLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQII
Sbjct: 961  TLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQII 1020

Query: 1021 KAAFMKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXGKFKKTFVLNRPPPLWTDG 1080
            KAAFMKPFIDTLESVHLIYAAED                  GKFKKTFVLNRPPPLWTDG
Sbjct: 1021 KAAFMKPFIDTLESVHLIYAAEDVTELTYREVLEERRRESRGKFKKTFVLNRPPPLWTDG 1080

Query: 1081 VGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDETEPSGSS 1140
            VGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDETEPSGSS
Sbjct: 1081 VGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDETEPSGSS 1140

Query: 1141 KI 1142
            KI
Sbjct: 1141 KI 1142



>gi|71400421|ref|XP_803046.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi strain
            CL Brener]
 gi|70865614|gb|EAN81600.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi]
          Length = 1142

 Score = 1597 bits (4136), Expect = 0.0,   Method: Composition-based stats.
 Identities = 768/1143 (67%), Positives = 902/1143 (78%), Gaps = 2/1143 (0%)

Query: 1    MVDGRSSASIXXXXXXXXXXXXXXXXXXLLQDSPLHTTMQYATSGLELTVPYALKVVASA 60
            M DGRSSAS+                  LL+DSPL T +QY T+GLELTVP+ LKVVA A
Sbjct: 1    MADGRSSASVVAVDPEKAARERDEAARALLRDSPLQTHLQYMTNGLELTVPFTLKVVAEA 60

Query: 61   DTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVMACCQ 120
              F RAKEVADEVLR AW LADTVLN+FNPNSE+S++GRLPVGQKH MSA LK V+ CCQ
Sbjct: 61   VAFSRAKEVADEVLRSAWHLADTVLNNFNPNSEISMIGRLPVGQKHTMSATLKSVITCCQ 120

Query: 121  RVYNSSAGCFDPSTAPVAKALR-EIALGKERNNACLEALTQACTLPNSFVIDFEAGTISR 179
             V+NSS G FDP+T P+ +ALR ++A     ++  +E L + C   +SF++D E GTI+R
Sbjct: 121  HVFNSSRGVFDPATGPIIEALRAKVAEKASVSDEQMEKLFRVCNFSSSFIVDLEMGTIAR 180

Query: 180  KHEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVGITRP 239
            KHE A  DLGGVSKGYIVDYV++ +NAAG  +V+F+WGGDCRASG NAR TPW+VGI RP
Sbjct: 181  KHEDARFDLGGVSKGYIVDYVVERLNAAGIVDVYFEWGGDCRASGTNARRTPWMVGIIRP 240

Query: 240  PSLDMLRNPPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKAKELMKPSQ 299
            PSL+ LRNPPK+ SYI V+ L++EAL TSGDYENL   ++ K  T  +DWK + L++P +
Sbjct: 241  PSLEQLRNPPKDPSYIRVLPLNDEALCTSGDYENLTEGSNKKLYTSIFDWKKRSLLEPVE 300

Query: 300  SNIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWXXXXXXXXXXXXXXXENERVA 359
            S +AQVS++CYSAMYADALATA  IKRD  KVRQ+L+ W               + ERVA
Sbjct: 301  SELAQVSIRCYSAMYADALATASLIKRDIKKVRQMLEDWRHVRNRVTNYVTYTRQGERVA 360

Query: 360  KMFEIATEDAEMRKRRISNTLPARVIVVXXXXXXXXXXXXXXXCGAQVVLMEKEAKLGGN 419
            +MFEIAT++AE+RK+RI+ +LPARVIVV               CGAQV+L+EKE K+GGN
Sbjct: 361  RMFEIATDNAEIRKKRIAGSLPARVIVVGGGLAGLSAAIEATACGAQVILLEKEPKVGGN 420

Query: 420  SAKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWL 479
            SAKATSGINGWGTRAQA+  + D GKYFERDT+KSG+GG+TDP LV+TLS+KS DAI WL
Sbjct: 421  SAKATSGINGWGTRAQAEQDVYDSGKYFERDTHKSGLGGSTDPGLVRTLSVKSGDAISWL 480

Query: 480  TSLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMEN 539
            +SLGVPLTVLSQLGGHSRKRTHRAPDK DGTP+PIGFTIM+TLE HVR  L+ R+TIMEN
Sbjct: 481  SSLGVPLTVLSQLGGHSRKRTHRAPDKADGTPVPIGFTIMQTLEQHVRTKLADRVTIMEN 540

Query: 540  CSVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLR 599
             +VTSLLS+++ R DG KQ+RV GVE  Q     + ILADAVILATGGFSNDKT +SLL+
Sbjct: 541  TTVTSLLSKSRVRHDGAKQVRVYGVEVLQDEGVVSRILADAVILATGGFSNDKTPNSLLQ 600

Query: 600  EHAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGP 659
            E AP L  FPTTNGPWATGDGVKLA+ LG +LVDMDKVQLHPTGLI+PKDPANPTK+LGP
Sbjct: 601  EFAPQLSGFPTTNGPWATGDGVKLARELGVKLVDMDKVQLHPTGLIDPKDPANPTKYLGP 660

Query: 660  EALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLF 719
            EALRGSGGVLLNK+G+RFVNELDLRSVVS AI+EQG EYP +GGS FA+CVLN AA KLF
Sbjct: 661  EALRGSGGVLLNKKGERFVNELDLRSVVSNAIIEQGDEYPDAGGSKFAFCVLNDAAVKLF 720

Query: 720  GVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVY 779
            GV+SH FYWK++GLFVKADT+  LAALIGCPVE+V+ TL +YE+LS   R CP TRK VY
Sbjct: 721  GVNSHGFYWKRLGLFVKADTVEKLAALIGCPVENVRNTLGDYEQLSKENRQCPKTRKVVY 780

Query: 780  PCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXXXXX 839
            PCV+G +GP+YVAFVTPSIHYTMGGCLISPSAE+Q++  ++ +P  H  PI GLF     
Sbjct: 781  PCVVGPQGPFYVAFVTPSIHYTMGGCLISPSAEMQLEENTT-SPFGHRRPIFGLFGAGEV 839

Query: 840  XXXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYG 899
                        NSLLECVVFGRIAGDRA+TILQ+K   LSFK WTTV+LREVREGG+YG
Sbjct: 840  TGGVHGGNRLGGNSLLECVVFGRIAGDRAATILQKKPVPLSFKTWTTVILREVREGGMYG 899

Query: 900  AGSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDK 959
             GSRVLRFNLPGALQRSGL LGQFIAIRG+WDGQQLIGYYSPITLPDDLG+I ILARSDK
Sbjct: 900  TGSRVLRFNLPGALQRSGLQLGQFIAIRGEWDGQQLIGYYSPITLPDDLGVIGILARSDK 959

Query: 960  GTLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQI 1019
            GTL+EWISALEPGDAVEMK CGGLVIERR S+++  F GH + KLCLIAGGTGVAPMLQI
Sbjct: 960  GTLKEWISALEPGDAVEMKGCGGLVIERRFSERYLYFSGHALKKLCLIAGGTGVAPMLQI 1019

Query: 1020 IKAAFMKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXGKFKKTFVLNRPPPLWTD 1079
            I+AA  KPF++ +ES+ LIYAAED                  GKF+  FVLNRPPP+WTD
Sbjct: 1020 IRAALKKPFLENIESIRLIYAAEDVSELTYRELLEHHQRDSKGKFRSIFVLNRPPPIWTD 1079

Query: 1080 GVGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDETEPSGS 1139
            GVGFID+ +L++ VQPP+ +LLVAICGPP+MQR+VK  LK+LGY+M LVRTVDE E   S
Sbjct: 1080 GVGFIDKKLLSSSVQPPAKDLLVAICGPPIMQRVVKTCLKSLGYDMQLVRTVDEVETQNS 1139

Query: 1140 SKI 1142
            SK+
Sbjct: 1140 SKM 1142



>gi|72547417|ref|XP_843225.1| NADH-dependent fumarate reductase, putative [Leishmania major strain
            Friedlin]
 gi|70905704|gb|AAZ14343.1| NADH-dependent fumarate reductase, putative [Leishmania major strain
            Friedlin]
          Length = 1147

 Score = 1379 bits (3570), Expect = 0.0,   Method: Composition-based stats.
 Identities = 706/1152 (61%), Positives = 846/1152 (73%), Gaps = 15/1152 (1%)

Query: 1    MVDGRSSASIXXXXXXXXXXXXXXXXXXLLQD---SPLHTTMQYATSGLELTVPYALKVV 57
            M DG++SAS+                  +LQD   SP+    Q    GL  TVPY LKVV
Sbjct: 1    MADGKTSASVVAVDAESAAKERDAAARAMLQDGGVSPVGKA-QLLKKGLVHTVPYTLKVV 59

Query: 58   -ASADTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVM 116
             A     ++A   A+EVL+ A+Q+ DT+LNSFN NSEVS + R+PVG++HQMSA LK VM
Sbjct: 60   VADPKEMEKATADAEEVLQSAFQVVDTLLNSFNENSEVSRINRMPVGEEHQMSAALKHVM 119

Query: 117  ACCQRVYNSSAGCFDPSTAPVAKALREIA-LGKERNNACLEALTQACTLPNSFVIDFEAG 175
            ACCQ+VYNSS G FDP+  P+ + LRE A  GK      +  L   CTL  SF ID   G
Sbjct: 120  ACCQKVYNSSRGAFDPAVGPLVRELREAAHKGKTVPAERVNDLLSKCTLNASFSIDMNRG 179

Query: 176  TISRKHEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVG 235
             I+RKH  A LDLGGV+KGY +DY ++ +N+ G+ +VFF+WGGD RASG N    PW VG
Sbjct: 180  MIARKHADAMLDLGGVNKGYGIDYTVERLNSLGYDDVFFEWGGDVRASGKNQSIQPWAVG 239

Query: 236  ITRPPSLDMLRN--PPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKAKE 293
            I RPP+L  +R   P  + S+I V+ L+NEA+ATSGDYENLI T   K  + T+D  +K 
Sbjct: 240  IVRPPALADIRTVVPKDKRSFIRVVHLNNEAIATSGDYENLIETPASKVYSSTFDRASKN 299

Query: 294  LMKPSQSNIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWXXXXXXXXXXXXXXX 353
            L++P+++ +AQVSVKCYS MYADALATA  +K DPA VR++LD W               
Sbjct: 300  LLEPTEAGMAQVSVKCYSCMYADALATAALLKNDPAAVRRMLDNWRYVRDTVTDYTTYTR 359

Query: 354  ENERVAKMFEIATEDAEMRKRRISNTLPARVIVVXXXXXXXXXXXXXXXCGAQVVLMEKE 413
            E ERVAKM EIATEDAEMR +RI  +LPARVI+V               CGAQV+L+EKE
Sbjct: 360  EGERVAKMLEIATEDAEMRAKRIKGSLPARVIIVGGGLAGCSAAIEAANCGAQVILLEKE 419

Query: 414  AKLGGNSAKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSA 473
             KLGGNSAKATSGIN WGTRAQAK  I+DGGK+FERDT++SG GGN DP LVKTLS+KS+
Sbjct: 420  PKLGGNSAKATSGINAWGTRAQAKQGIMDGGKFFERDTHRSGKGGNCDPCLVKTLSVKSS 479

Query: 474  DAIGWLTSLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGR 533
            DA+ WL+ LGVPLTVLSQLGG SRKR HRAPDK DGTP+P+GFTIMKTLE+H+  NLS  
Sbjct: 480  DAVKWLSELGVPLTVLSQLGGASRKRCHRAPDKSDGTPVPVGFTIMKTLENHIVNNLSRH 539

Query: 534  ITIMENCSVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTIL-ADAVILATGGFSNDK 592
            +T+M   +VT+L S +  RPDG     VTGV   QA SG++ +L ADAVILATGGFSND 
Sbjct: 540  VTVMTGITVTALESTSHVRPDGVLVKHVTGVRLIQA-SGQSMVLNADAVILATGGFSNDH 598

Query: 593  TADSLLREHAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPAN 652
            T +SLL+++AP L +FPTTNG WATGDGVK+A +LG  LVDMDKVQLHPTGLI+PKDP+N
Sbjct: 599  TPNSLLQQYAPQLSSFPTTNGVWATGDGVKMASKLGVALVDMDKVQLHPTGLIDPKDPSN 658

Query: 653  PTKFLGPEALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLN 712
             TK+LGPEALRGSGGVLLNK G+RFVNELDLRSVVS+AI+ Q   YPGSGGS FAYCVLN
Sbjct: 659  RTKYLGPEALRGSGGVLLNKNGERFVNELDLRSVVSQAIIAQDNVYPGSGGSKFAYCVLN 718

Query: 713  AAAQKLFGVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQ-RSC 771
              A KLFG +   FYW ++GLF K+D++  LA LIGCP  +V  TL++YE LS+ +   C
Sbjct: 719  ETAAKLFGKNFLGFYWNRLGLFQKSDSVAGLAKLIGCPEANVMATLKQYEELSSKKLNPC 778

Query: 772  PITRKSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPIL 831
            P+T K+V+PCVLGT+GPYYVA +TPSIHYTMGGCLISPSAE+Q K+ S   P+    PIL
Sbjct: 779  PLTGKNVFPCVLGTQGPYYVALITPSIHYTMGGCLISPSAEMQTKDNSGVTPVRR--PIL 836

Query: 832  GLFXXXXXXXXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLRE 891
            GLF                 NSLLECVVFG+IAGDRA+TILQ+K++ LS   W+TVVLRE
Sbjct: 837  GLFGAGEVTGGVHGGNRLGGNSLLECVVFGKIAGDRAATILQKKNTGLSMTEWSTVVLRE 896

Query: 892  VREGGVYGAGSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMI 951
            VREGGVYGAGSRVLRFN+PGALQ++GL+LGQFI IRGDWDG +LIGYYSPITLPDD+G+I
Sbjct: 897  VREGGVYGAGSRVLRFNMPGALQKTGLALGQFIGIRGDWDGHRLIGYYSPITLPDDVGVI 956

Query: 952  DILARSDKGTLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGT 1011
             ILAR+DKG L EWISAL+PGDAVEMKACGGL+IERR +D+HF F GH I KL LI GGT
Sbjct: 957  GILARADKGRLAEWISALQPGDAVEMKACGGLIIERRFADRHFFFRGHKIRKLALIGGGT 1016

Query: 1012 GVAPMLQIIKAAFMKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXG-KFKKTFVL 1070
            GVAPMLQI++AA  KPF+D++ES+  IYAAED                    KFK  FVL
Sbjct: 1017 GVAPMLQIVRAAVKKPFVDSIESIQFIYAAEDVSELTYRTLLESYEKEYGSEKFKCHFVL 1076

Query: 1071 NRPPPLWTDGVGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRT 1130
            N PP  WTDGVGF+D  +L + VQ PS++LLVAICGPP+MQR VK  LK+LGYNMNLVRT
Sbjct: 1077 NNPPAQWTDGVGFVDTALLRSAVQAPSNDLLVAICGPPIMQRAVKGALKSLGYNMNLVRT 1136

Query: 1131 VDETEPSGSSKI 1142
            VDETEP+ S+KI
Sbjct: 1137 VDETEPT-SAKI 1147



>gi|146100731|ref|XP_001468931.1| NADH-dependent fumarate reductase [Leishmania infantum]
 gi|134073300|emb|CAM72026.1| NADH-dependent fumarate reductase, putative [Leishmania infantum]
          Length = 1147

 Score = 1375 bits (3560), Expect = 0.0,   Method: Composition-based stats.
 Identities = 702/1152 (60%), Positives = 846/1152 (73%), Gaps = 15/1152 (1%)

Query: 1    MVDGRSSASIXXXXXXXXXXXXXXXXXXLLQD---SPLHTTMQYATSGLELTVPYALKVV 57
            M DG++SAS+                  +LQD   SP+    Q    GL  TVPY LKVV
Sbjct: 1    MADGKTSASVVAVDAESAAKERDAAARAMLQDGGVSPVGKA-QLLKKGLVHTVPYTLKVV 59

Query: 58   -ASADTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVM 116
             A     ++A   A++VL+ A+Q+ DT+LN+FN NSEVS + R+PVG++HQMSA LK VM
Sbjct: 60   VADPKEMEKAAADAEQVLQAAFQVVDTLLNNFNENSEVSRINRMPVGEEHQMSAALKHVM 119

Query: 117  ACCQRVYNSSAGCFDPSTAPVAKALREIA-LGKERNNACLEALTQACTLPNSFVIDFEAG 175
            ACCQ+VYNSS G FDP+  P+ + LRE A  GK      +  L   CTL  SF ID   G
Sbjct: 120  ACCQKVYNSSRGAFDPAVGPLVRELREAAHKGKTVPAEHVNDLLSKCTLNASFSIDMNRG 179

Query: 176  TISRKHEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVG 235
             I+RKH  A LDLGGV+KGY +DY+++ +N+ G+ +VFF+WGGD RASG N  N PW VG
Sbjct: 180  MIARKHADAMLDLGGVNKGYGIDYIVERLNSLGYNDVFFEWGGDVRASGKNQSNQPWAVG 239

Query: 236  ITRPPSLDMLRN--PPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKAKE 293
            I RPP+L  +R   P  + S+I V+ L+NEA+ATSGDYENLI     K  + T+D  +K 
Sbjct: 240  IVRPPALADIRTVVPEDKRSFIRVVRLNNEAIATSGDYENLIEGPGSKVYSSTFDPASKN 299

Query: 294  LMKPSQSNIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWXXXXXXXXXXXXXXX 353
            L++P+++++AQVSVKCYS MYADALATA  +K DPA VR++LD W               
Sbjct: 300  LLEPTEADMAQVSVKCYSCMYADALATAALLKNDPAAVRRMLDNWRYVRDTVTDYTTYTR 359

Query: 354  ENERVAKMFEIATEDAEMRKRRISNTLPARVIVVXXXXXXXXXXXXXXXCGAQVVLMEKE 413
            E ERVAKM EIATEDAEMR +RI  +LPARVI+V               CGAQV+L+EKE
Sbjct: 360  EGERVAKMLEIATEDAEMRAKRIKGSLPARVIIVGGGLAGCSAAIEAANCGAQVILLEKE 419

Query: 414  AKLGGNSAKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSA 473
             KLGGNSAKATSGIN WGTRAQAK  ++DGGK+FERDT++SG GGN DP LVKTLS+KS+
Sbjct: 420  PKLGGNSAKATSGINAWGTRAQAKQGVMDGGKFFERDTHRSGKGGNCDPCLVKTLSVKSS 479

Query: 474  DAIGWLTSLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGR 533
            DA+ WL+ LGVPLTVLSQLGG SRKR HRAPDK DGTP+P+GFTIMKTLE+H+  NLS  
Sbjct: 480  DAVKWLSELGVPLTVLSQLGGASRKRCHRAPDKSDGTPVPVGFTIMKTLENHIVNNLSRH 539

Query: 534  ITIMENCSVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTIL-ADAVILATGGFSNDK 592
            +T+M   +VT+L S ++ RPDG     VTGV   Q+ SG++ +L ADAV+LATGGFSND 
Sbjct: 540  VTVMTGITVTALESTSRVRPDGVLVKHVTGVRLIQS-SGQSMVLNADAVVLATGGFSNDH 598

Query: 593  TADSLLREHAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPAN 652
            T +SLL+++AP L +FPTTNG WATGDGVK+A +LG  LVDMDKVQLHPTGL++PKDP+N
Sbjct: 599  TPNSLLQQYAPQLSSFPTTNGVWATGDGVKMASKLGVTLVDMDKVQLHPTGLLDPKDPSN 658

Query: 653  PTKFLGPEALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLN 712
             TK+LGPEALRGSGGVLLNK G+RFVNELDLRSVVS+AI+ Q   YPGSGGS FAYCVLN
Sbjct: 659  RTKYLGPEALRGSGGVLLNKNGERFVNELDLRSVVSQAIIAQDNVYPGSGGSKFAYCVLN 718

Query: 713  AAAQKLFGVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQ-RSC 771
              A KLFG +   FYW ++GLF K D++  LA LIGCP  +V  TL++YE LS+ +   C
Sbjct: 719  ETAAKLFGKNFLGFYWNRLGLFQKVDSVAGLAKLIGCPEANVMATLKQYEELSSKKLNPC 778

Query: 772  PITRKSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPIL 831
            P+T K+V+PCVLGT+GPYYVA VTPSIHYTMGGCLISPSAE+Q  + S   P+    PIL
Sbjct: 779  PLTGKNVFPCVLGTQGPYYVALVTPSIHYTMGGCLISPSAEMQTIDNSGVTPVRR--PIL 836

Query: 832  GLFXXXXXXXXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLRE 891
            GLF                 NSLLECVVFG+IAGDRA+TILQ+KS+ LS   W+TVVLRE
Sbjct: 837  GLFGAGEVTGGVHGGNRLGGNSLLECVVFGKIAGDRAATILQKKSTGLSTTEWSTVVLRE 896

Query: 892  VREGGVYGAGSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMI 951
            VREGGVYGAGSRVLRFN+PGALQR+GL+LGQFI IRGDWDG +LIGYYSPITLPDD+G+I
Sbjct: 897  VREGGVYGAGSRVLRFNMPGALQRTGLALGQFIGIRGDWDGHRLIGYYSPITLPDDVGVI 956

Query: 952  DILARSDKGTLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGT 1011
             ILAR+DKG L EWISAL+PGDAVEMKACGGL+IERR +D+HF F GH I KL LI GGT
Sbjct: 957  GILARADKGRLAEWISALQPGDAVEMKACGGLIIERRFADRHFFFRGHKIRKLALIGGGT 1016

Query: 1012 GVAPMLQIIKAAFMKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXG-KFKKTFVL 1070
            GVAPMLQI++AA  KPF+D++ES+  IYAAED                    KFK  FVL
Sbjct: 1017 GVAPMLQIVRAAVKKPFVDSIESIQFIYAAEDVSELTYRTLLESYEKEYGSEKFKCHFVL 1076

Query: 1071 NRPPPLWTDGVGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRT 1130
            N PP  WTDGVGF+D  +L + VQ PS++LLVAICGPP+MQR VK  LK LGYNMNLVRT
Sbjct: 1077 NNPPAQWTDGVGFVDTALLRSAVQAPSNDLLVAICGPPIMQRAVKGALKGLGYNMNLVRT 1136

Query: 1131 VDETEPSGSSKI 1142
            VDETEP+ S+KI
Sbjct: 1137 VDETEPT-SAKI 1147



>gi|154344555|ref|XP_001568219.1| NADH-dependent fumarate reductase, putative [Leishmania braziliensis
            MHOM/BR/75/M2904]
 gi|134065556|emb|CAM43326.1| NADH-dependent fumarate reductase, putative [Leishmania braziliensis]
          Length = 1147

 Score = 1366 bits (3535), Expect = 0.0,   Method: Composition-based stats.
 Identities = 694/1146 (60%), Positives = 840/1146 (73%), Gaps = 14/1146 (1%)

Query: 1    MVDGRSSASIXXXXXXXXXXXXXXXXXXLLQD---SPLHTTMQYATSGLELTVPYALK-V 56
            M DG++SAS+                  +LQD   SP+    Q    GL   VPY LK V
Sbjct: 1    MADGKTSASVVAVDPERAAKERDAAARAMLQDGGVSPVGKA-QLLKKGLAYAVPYTLKIV 59

Query: 57   VASADTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVM 116
            VA     ++     ++VL+ A+Q+ DT+LN+FN NSEVS + R+PVG++HQMSA LKRVM
Sbjct: 60   VADPKAMEKTTADVEKVLQTAFQVVDTLLNNFNENSEVSRINRMPVGEEHQMSAALKRVM 119

Query: 117  ACCQRVYNSSAGCFDPSTAPVAKALREIAL-GKERNNACLEALTQACTLPNSFVIDFEAG 175
             CCQRVYNSS G FDP+  P+ + LRE A  G+      + AL   CTL  SF ID   G
Sbjct: 120  GCCQRVYNSSRGAFDPAVGPLVRELREAAREGRTLPAERINALLSKCTLNISFSIDLNRG 179

Query: 176  TISRKHEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVG 235
            TI+RKH  A LDLGGV+KGY VDYV++++N  G+ +VFF+WGGD RASG N  N  WVVG
Sbjct: 180  TIARKHADAMLDLGGVNKGYGVDYVVEHLNNLGYDDVFFEWGGDVRASGKNPSNQHWVVG 239

Query: 236  ITRPPSLDMLRN--PPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKAKE 293
            I RPP+L  +R   P  + S+I V+ L++EA+ATSGDYENL+     K  + T++  +K 
Sbjct: 240  IARPPALADIRTVVPQDKQSFIRVVCLNDEAIATSGDYENLVEGPGSKVYSSTFNATSKS 299

Query: 294  LMKPSQSNIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWXXXXXXXXXXXXXXX 353
            L++P+++NIAQVSVKCYS MYADALATA  +K +P  VR++LD W               
Sbjct: 300  LLEPTETNIAQVSVKCYSCMYADALATAALLKNNPTAVRRMLDNWRYVRDTVTDYTTYSR 359

Query: 354  ENERVAKMFEIATEDAEMRKRRISNTLPARVIVVXXXXXXXXXXXXXXXCGAQVVLMEKE 413
            E ERVAKMFEIATED EMR +RIS +LPARVI+V               CGAQV+L+EKE
Sbjct: 360  EGERVAKMFEIATEDKEMRAKRISGSLPARVIIVGGGLAGCSAAIEAVNCGAQVILLEKE 419

Query: 414  AKLGGNSAKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSA 473
            AK+GGNSAKATSGIN WGTRAQAK  ++DGGK+FERDT++SG GG+ DP LVKTLS+KS+
Sbjct: 420  AKIGGNSAKATSGINAWGTRAQAKQGVMDGGKFFERDTHRSGKGGHCDPCLVKTLSVKSS 479

Query: 474  DAIGWLTSLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGR 533
            DA+ WL+ LGVPLTVLSQLGG SRKR HRAPDK DGTP+PIGFTIMKTLE+H+  +LS +
Sbjct: 480  DAVKWLSELGVPLTVLSQLGGASRKRCHRAPDKSDGTPVPIGFTIMKTLENHIINDLSHQ 539

Query: 534  ITIMENCSVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTIL-ADAVILATGGFSNDK 592
            +T+M    VT L S +  RPDG     VTGV   Q G G++ +L ADAVILATGGFSND 
Sbjct: 540  VTVMTGIKVTGLESTSHARPDGVLVKHVTGVRLIQ-GDGQSRVLNADAVILATGGFSNDH 598

Query: 593  TADSLLREHAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPAN 652
            TA+SLL+++AP L +FPTTNG WATGDGVK A+ LG +LVDMDKVQLHPTGL++PKDP+N
Sbjct: 599  TANSLLQQYAPQLSSFPTTNGVWATGDGVKAARELGVELVDMDKVQLHPTGLLDPKDPSN 658

Query: 653  PTKFLGPEALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLN 712
             TK+LGPEALRGSGGVLLNK G+RFVNELDLRSVVS+AI+EQ   YPGSGGS FAYCVLN
Sbjct: 659  RTKYLGPEALRGSGGVLLNKNGERFVNELDLRSVVSQAIIEQNNVYPGSGGSKFAYCVLN 718

Query: 713  AAAQKLFGVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQ-RSC 771
             AA KLFG +   FYW ++GLF K + +  LA LIGCP E+V  TL+EY+ LS+ +  +C
Sbjct: 719  EAAAKLFGKNFLGFYWHRLGLFEKVEDVAGLAKLIGCPEENVTATLKEYKELSSKKLHAC 778

Query: 772  PITRKSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPIL 831
            P+T K+V+PC LGT+GPYYVAFVTPSIHYTMGGCLISPSAE+Q  + +   P+    PIL
Sbjct: 779  PLTNKNVFPCTLGTEGPYYVAFVTPSIHYTMGGCLISPSAEMQTIDNTGVTPVRR--PIL 836

Query: 832  GLFXXXXXXXXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLRE 891
            GLF                 NSLLECVVFGRIAGDRA+TILQ+K++ LS   W+TVVLRE
Sbjct: 837  GLFGAGEVTGGVHGGNRLGGNSLLECVVFGRIAGDRAATILQKKNAGLSMTEWSTVVLRE 896

Query: 892  VREGGVYGAGSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMI 951
            VREGGVYG GSRVLRFN+PGALQ++GL+LGQFIA+RGDWDGQQL+GYYSPITLPDD+G+I
Sbjct: 897  VREGGVYGTGSRVLRFNMPGALQKTGLALGQFIAMRGDWDGQQLLGYYSPITLPDDIGVI 956

Query: 952  DILARSDKGTLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGT 1011
             ILAR+DKG L EWISAL+PGDAVEMKACGGL+I RR + +H  F  H I KL LI GGT
Sbjct: 957  GILARADKGRLAEWISALQPGDAVEMKACGGLIIHRRFAARHLFFRSHKIRKLALIGGGT 1016

Query: 1012 GVAPMLQIIKAAFMKPFIDTLESVHLIYAAEDXXXXX-XXXXXXXXXXXXXGKFKKTFVL 1070
            GVAPMLQI++AA  KPF+D++ES+  IYAAED                   GKFK  FVL
Sbjct: 1017 GVAPMLQIVRAAVKKPFVDSIESIQFIYAAEDVSELTYRTLLESYEKEYGSGKFKCHFVL 1076

Query: 1071 NRPPPLWTDGVGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRT 1130
            N PP  WT+GVGF+D  +L + VQ PS++LLVAICGPP+MQR VK+ LK LGYNMNLVRT
Sbjct: 1077 NNPPSQWTEGVGFVDTALLRSAVQAPSNDLLVAICGPPIMQRAVKSALKGLGYNMNLVRT 1136

Query: 1131 VDETEP 1136
            VDE EP
Sbjct: 1137 VDEPEP 1142



>gi|71410008|ref|XP_807320.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi strain
            CL Brener]
 gi|70871295|gb|EAN85469.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi]
          Length = 1215

 Score = 1308 bits (3384), Expect = 0.0,   Method: Composition-based stats.
 Identities = 664/1154 (57%), Positives = 821/1154 (71%), Gaps = 29/1154 (2%)

Query: 3    DGRSSASIXXXXXXXXXXXXXXXXXXLL-QDSP-------LHTTMQYATSGLELTVPYAL 54
            DGRSSASI                  +L Q+ P       L  TM+    GLE TVPY L
Sbjct: 62   DGRSSASIVVVDAELAAKERDRIAREMLSQNMPSPHAEERLVVTMR----GLEHTVPYTL 117

Query: 55   KVVASADTFDRAKEV-ADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLK 113
            ++V +     +  EV A +VL+ A+++ D  LN +NP SEVS + +LP+G KH MS  ++
Sbjct: 118  RIVLNGPNEAKNGEVIAGKVLKEAFEVVDQHLNHYNPESEVSAINQLPLGAKHTMSQHMR 177

Query: 114  RVMACCQRVYNSSAGCFDPSTAPVAKALREIALGKERNNA---CLEALTQACTLPNSFVI 170
            RVM CC RVY SS  CFDP+T P+ + LR + +  E+++A     E   +   LP SF +
Sbjct: 178  RVMECCVRVYASSGACFDPATGPLVEFLRSV-MKDEKSDAESTLTEEEVERFCLPQSFDV 236

Query: 171  DFEAGTISRKHEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNT 230
            +   GTI+RKHE A LDLGGV+KGY VD V++ +NAAG ++V F+WGGDCRA+G+N ++ 
Sbjct: 237  NMTDGTIARKHEGAKLDLGGVNKGYTVDRVVEKLNAAGMRDVMFEWGGDCRATGVNYQHQ 296

Query: 231  PWVVGITRPPSLDMLRNPPKE--------ASYISVISLDNEALATSGDYENLIYTADDKP 282
            PW + I RPP ++++    KE        +  + ++ LD+EAL TSGDYEN++Y+     
Sbjct: 297  PWAIAIVRPPPVEVVEQHAKEGLDEKKEASQLLRLMYLDDEALCTSGDYENVMYSPKYGV 356

Query: 283  LTCTYDWKAKELMKPSQSNIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWXXXX 342
             +  +DWK + L++P +S +AQVS+KCYSAMYADALATA  IKRD +KVR +L+ W    
Sbjct: 357  RSNIFDWKKRSLLEPVESELAQVSIKCYSAMYADALATASLIKRDISKVRHMLEEWRHSR 416

Query: 343  XXXXXXXXXXXENERVAKMFEIATEDAEMRKRRISNTLPARVIVVXXXXXXXXXXXXXXX 402
                       + ERVA+MFEIATE+AE+RK RI+ +LPARVIVV               
Sbjct: 417  NRVTNYVTYTRQGERVARMFEIATENAEIRKNRIAGSLPARVIVVGCGLAGLSAAIEATA 476

Query: 403  CGAQVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDP 462
            CGAQV+L+EKE K+GGNSAKATSGINGWGTRAQA   I D    FERDT+KSG+GG+T P
Sbjct: 477  CGAQVILLEKEPKVGGNSAKATSGINGWGTRAQALDDIQDNCNIFERDTHKSGLGGSTVP 536

Query: 463  ALVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTL 522
            +LV+TLS+KS DAI WL+SLGVPLTVLSQLGGHSRKRTHRAPDK DGTP+PIGFTIM+TL
Sbjct: 537  SLVRTLSVKSGDAISWLSSLGVPLTVLSQLGGHSRKRTHRAPDKADGTPVPIGFTIMRTL 596

Query: 523  EDHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRVTGVEFTQAG---SGKTTILAD 579
            E HVR  L+ R+TIME+  VTSLL+E K  PDG +++RVTGV + ++    +G   + AD
Sbjct: 597  EQHVRTKLADRVTIMESTVVTSLLNEIKGTPDGGREVRVTGVTYKKSDEKEAGSMKLTAD 656

Query: 580  AVILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQL 639
            AVILATGGFSND  + SL+ E AP L  FPTTNGPWATGDGVKLA+RLGA LVDM+KVQL
Sbjct: 657  AVILATGGFSNDHMSQSLIGEFAPELSGFPTTNGPWATGDGVKLARRLGATLVDMEKVQL 716

Query: 640  HPTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYP 699
            HPTGLI+PKDPANPTK+LGPEALRGSGGVLLNK+G+RFVNEL+LRSVVS AI+EQG EYP
Sbjct: 717  HPTGLIDPKDPANPTKYLGPEALRGSGGVLLNKKGERFVNELELRSVVSNAIIEQGDEYP 776

Query: 700  GSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLE 759
             SGGS FA+CVLN AA KLFGV+   FY   +G+F + D ++ LA LIGC V ++Q TLE
Sbjct: 777  YSGGSKFAFCVLNDAAVKLFGVNLLNFYANTLGVFKRVDDLQGLAMLIGCDVLTLQNTLE 836

Query: 760  EYERLSTSQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTS 819
             YE  S    +CP T K VYPCV+G +GP+YVAFVTPSIHYTMGGCLISPSAEIQ ++ S
Sbjct: 837  TYESSSIVTSACPFTGKVVYPCVVGPQGPFYVAFVTPSIHYTMGGCLISPSAEIQREHYS 896

Query: 820  SRAPLSHSNPILGLFXXXXXXXXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSAL 879
                L +  PILGLF                 NSLLECVVFGRIAGDRA+TILQ++  AL
Sbjct: 897  LNL-LENQRPILGLFGAGEVTGGVHGGNRLGGNSLLECVVFGRIAGDRAATILQKQVYAL 955

Query: 880  SFKVWTTVVLREVREGGVYGAGSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYY 939
            S   WT+VV+RE R G  +G GSRVLRFNLPGALQRSGL LGQFIAIRG+WDGQQLIGYY
Sbjct: 956  SKDKWTSVVVRESRSGERFGTGSRVLRFNLPGALQRSGLYLGQFIAIRGEWDGQQLIGYY 1015

Query: 940  SPITLPDDLGMIDILARSDKGTLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGH 999
            SPITLPD+ G+I ILAR DKGTL+EWISA+ PGD+VE+K+CGG++IER  + K F+F GH
Sbjct: 1016 SPITLPDERGVISILARGDKGTLKEWISAMRPGDSVEIKSCGGILIERNPAKKQFLFHGH 1075

Query: 1000 IINKLCLIAGGTGVAPMLQIIKAAFMKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXX 1059
            +I +  LIAGG+GVAPMLQII+AA  +P++DT ES+ L+Y AE+                
Sbjct: 1076 VIRQFGLIAGGSGVAPMLQIIRAALERPYVDTTESIRLVYTAEEYEELTYRELLHHYSKE 1135

Query: 1060 XXGKFKKTFVLNRPPPLWTDGVGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLK 1119
               KF   F LN PP  WT GVGF+DR  L   +QPPS++LL+AICGPP MQR +K  L 
Sbjct: 1136 NPDKFSVEFSLNNPPEGWTGGVGFVDRPSLRKTLQPPSNDLLIAICGPPAMQRAMKNDLL 1195

Query: 1120 TLGYNMNLVRTVDE 1133
             +GYN  LV TVD+
Sbjct: 1196 AMGYNPALVHTVDD 1209



>gi|71747118|ref|XP_822614.1| NADH-dependent fumarate reductase [Trypanosoma brucei TREU927]
 gi|70832282|gb|EAN77786.1| NADH-dependent fumarate reductase, putative [Trypanosoma brucei]
          Length = 1232

 Score = 1250 bits (3234), Expect = 0.0,   Method: Composition-based stats.
 Identities = 641/1165 (55%), Positives = 790/1165 (67%), Gaps = 44/1165 (3%)

Query: 3    DGRSSASIXXXXXXXXXXXXXXXXXXLL--------QDSPLHTTMQYATSGLELTVPYAL 54
            DG SSASI                  LL        +D P    ++    GLE T+PY L
Sbjct: 71   DGISSASIVVTDPEAAAKKRDRMARELLSSNSGLCQEDEPTIINLK----GLEHTIPYRL 126

Query: 55   KVV-ASADTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLK 113
             VV  ++ +    +  A E+LR A+ + D  LN FNP SE+S V  LPVG+KHQMS  L+
Sbjct: 127  AVVLCNSRSTGEFEAKAAEILRKAFHMVDYSLNCFNPESELSRVNSLPVGEKHQMSEDLR 186

Query: 114  RVMACCQRVYNSSAGCFDPSTAPVAKALREIALGKERNN------ACLEALTQACTLPNS 167
             VM C   V++SS   FDP+  P+   LR    G  R++      +  EA  +  +L  S
Sbjct: 187  HVMECTISVHHSSGMGFDPAAGPIISRLR----GAMRDHNDMSDISVTEAEVELFSLAQS 242

Query: 168  FVIDFEAGTISRKHEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNA 227
            F +D E GTI+RKH  A LDLGGV+KGY VDYV+D++ AAG  NV F+WGGD RASG N 
Sbjct: 243  FDVDLEEGTIARKHSEARLDLGGVNKGYTVDYVVDHLRAAGMPNVLFEWGGDIRASGRNI 302

Query: 228  RNTPWVVGITRPPSLDMLRNPPK-----------------EASYISVISLDNEALATSGD 270
            +   W V I RPPS++ +    K                   S + V+ LD+EAL TSGD
Sbjct: 303  KGNLWAVAIKRPPSVEEVIRRAKGKMLKMGEEEQEEKDDDSPSLLHVVELDDEALCTSGD 362

Query: 271  YENLIYTADDKPLTCTYDWKAKELMKPSQSNIAQVSVKCYSAMYADALATACFIKRDPAK 330
            YEN++Y          +DW+ + L+ P +  +AQVSVKCYSAMYADALAT C +KRD  +
Sbjct: 363  YENVLYHPKHGVAGSIFDWQRRGLLSPEEGALAQVSVKCYSAMYADALATVCLVKRDAVR 422

Query: 331  VRQLLDGWXXXXXXXXXXXXXXXENERVAKMFEIATEDAEMRKRRISNTLPARVIVVXXX 390
            +R LL+GW               + ER+A M EIA E  E+R+ RI+ +LP+R+++V   
Sbjct: 423  IRYLLEGWRYVRSRVTNYFAYTRQGERLAHMHEIAQETRELREIRIAGSLPSRIVIVGGG 482

Query: 391  XXXXXXXXXXXXCGAQVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVDGGKYFERD 450
                        CGAQV+LMEKE ++GGNSAKATSGINGWGTR QAK+ I+DGGKYFERD
Sbjct: 483  LAGLSAAIEAASCGAQVILMEKEGRIGGNSAKATSGINGWGTRTQAKSDILDGGKYFERD 542

Query: 451  TYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHRAPDKKDGT 510
            T+ SG+GG TDPALVK LS+KS DAIGWLTSLGVPL+VLSQLGGHS KRTHRAPDK DGT
Sbjct: 543  TFLSGVGGTTDPALVKVLSVKSGDAIGWLTSLGVPLSVLSQLGGHSFKRTHRAPDKTDGT 602

Query: 511  PLPIGFTIMKTLEDHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRVTGVEF---T 567
            PLPIG TIM+TLEDH+R NLS R+TIM + SVT LL ET   PDG  ++RVTGV +   +
Sbjct: 603  PLPIGHTIMRTLEDHIRNNLSERVTIMTHVSVTELLHETDTTPDGASEVRVTGVRYRDLS 662

Query: 568  QAGSGKTTILADAVILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWATGDGVKLAQRL 627
                  + +LADAV+LATGGFSND+  +SLL ++APHL +FPTTNGPWATGDGVKLA  +
Sbjct: 663  DVDGQPSKLLADAVVLATGGFSNDREENSLLCKYAPHLASFPTTNGPWATGDGVKLATSV 722

Query: 628  GAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELDLRSVV 687
            GA+LVDMDKVQLHPTGLI+PKDPAN TK LGPEALRGSGG+LLNKQGKRFVNELDLRSVV
Sbjct: 723  GAKLVDMDKVQLHPTGLIDPKDPANTTKILGPEALRGSGGILLNKQGKRFVNELDLRSVV 782

Query: 688  SKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRDLAALI 747
            SKAI  QG EYPGSGG  FAYCVLN  A  LFG  +  FY KK+GLF +A+T+ +LA LI
Sbjct: 783  SKAINTQGNEYPGSGGCYFAYCVLNEDATNLFGGGALGFYGKKLGLFQRAETVEELAKLI 842

Query: 748  GCPVESVQQTLEEYERLSTSQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLI 807
            GC    ++ TLE+YE  S ++ +CP+T K V+PCV+GT+GPY VAFVTPSIHYTMGGCLI
Sbjct: 843  GCDEGELRDTLEKYETCSKAKVACPVTGKVVFPCVVGTRGPYNVAFVTPSIHYTMGGCLI 902

Query: 808  SPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXXXXXXXXXXXXXNSLLECVVFGRIAGDR 867
            SP+AE+ ++       L +  PI  LF                 NSLLECVVFG+IAGDR
Sbjct: 903  SPAAEV-LQEYKGLNILENHRPIRCLFGAGEVTGGVHGGNRLGGNSLLECVVFGKIAGDR 961

Query: 868  ASTILQRKSSALSFKVWTTVVLREVREGGVYGAGSRVLRFNLPGALQRSGLSLGQFIAIR 927
            A+TILQ++  ALS   WT+VV+RE R G  +G GSRVLRFNLPGALQR+GL+LG+F+AIR
Sbjct: 962  AATILQKREIALSKTSWTSVVVRESRSGEQFGTGSRVLRFNLPGALQRTGLNLGEFVAIR 1021

Query: 928  GDWDGQQLIGYYSPITLPDDLGMIDILARSDKGTLREWISALEPGDAVEMKACGGLVIER 987
            G+WDGQQL+GY+SPITLP+DLG I +L R+DKGTL+EWI AL PGD+VE+KACGGL I++
Sbjct: 1022 GEWDGQQLVGYFSPITLPEDLGTISLLVRADKGTLKEWICALRPGDSVEIKACGGLRIDQ 1081

Query: 988  RLSDKHFVFMGHIINKLCLIAGGTGVAPMLQIIKAAFMKPFIDTLESVHLIYAAEDXXXX 1047
                K  +F    I +  L+A GTGVAPMLQ+I+AA  KP++DTLES+ LIYAAE+    
Sbjct: 1082 DPVKKCLLFRNRPITRFALVAAGTGVAPMLQVIRAALKKPYVDTLESIRLIYAAEEYDTL 1141

Query: 1048 XXXXXXXXXXXXXXGKFKKTFVLNRPPPLWTDGVGFIDRGILTNHVQPPSDNLLVAICGP 1107
                           KF   FVLN PP  WT GVGF+++  L   +QPPS   L+ +CGP
Sbjct: 1142 TYRSILQRFAEEFPDKFVCNFVLNNPPEGWTGGVGFVNKKSLQKVLQPPSSEPLIVVCGP 1201

Query: 1108 PVMQRIVKATLKTLGYNMNLVRTVD 1132
            PVMQR VK  L ++GY+  LV TVD
Sbjct: 1202 PVMQRDVKNELLSMGYDKELVHTVD 1226



>gi|60460036|gb|AAX20162.1| mitochondrial NADH-dependent fumarate reductase [Trypanosoma brucei]
          Length = 1232

 Score = 1247 bits (3226), Expect = 0.0,   Method: Composition-based stats.
 Identities = 640/1165 (54%), Positives = 789/1165 (67%), Gaps = 44/1165 (3%)

Query: 3    DGRSSASIXXXXXXXXXXXXXXXXXXLL--------QDSPLHTTMQYATSGLELTVPYAL 54
            DG SSASI                  LL        +D P    ++    GLE T+PY L
Sbjct: 71   DGISSASIVVTDPEAAAKKRDRMARELLSSNSGLCQEDEPTIINLK----GLEHTIPYRL 126

Query: 55   KVV-ASADTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLK 113
             VV  ++ +    +  A E+LR A+ + D  LN FNP SE+S V  LPVG+KHQMS  L+
Sbjct: 127  AVVLCNSRSTGEFEAKAAEILRKAFHMVDYSLNCFNPESELSRVNSLPVGEKHQMSEDLR 186

Query: 114  RVMACCQRVYNSSAGCFDPSTAPVAKALREIALGKERNN------ACLEALTQACTLPNS 167
             VM C   V++SS   FDP+  P+   LR    G  R++      +  EA  +  +L  S
Sbjct: 187  HVMECTISVHHSSGMGFDPAAGPIISRLR----GAMRDHNDMSDISVTEAEVELFSLAQS 242

Query: 168  FVIDFEAGTISRKHEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNA 227
            F +D E GTI+RKH  A LDLGGV+KGY VDYV+D++ AAG  NV F+WGGD RASG N 
Sbjct: 243  FDVDLEEGTIARKHSEARLDLGGVNKGYTVDYVVDHLRAAGMPNVLFEWGGDIRASGRNI 302

Query: 228  RNTPWVVGITRPPSLDMLRNPPK-----------------EASYISVISLDNEALATSGD 270
            +   W V I RPPS++ +    K                   S + V+ LD+EAL TSGD
Sbjct: 303  KGNLWAVAIKRPPSVEEVIRRAKGKMLKMGEEEQEEKDDDSPSLLHVVELDDEALCTSGD 362

Query: 271  YENLIYTADDKPLTCTYDWKAKELMKPSQSNIAQVSVKCYSAMYADALATACFIKRDPAK 330
            YEN++Y          +DW+ + L+ P +  +AQVSVKCYSAMYADALAT C +KRD  +
Sbjct: 363  YENVLYHPKHGVAGSIFDWQRRGLLSPEEGALAQVSVKCYSAMYADALATVCLVKRDAVR 422

Query: 331  VRQLLDGWXXXXXXXXXXXXXXXENERVAKMFEIATEDAEMRKRRISNTLPARVIVVXXX 390
            +R LL+GW               + ER+A M EIA E  E+R+ RI+ +LP+R+++V   
Sbjct: 423  IRYLLEGWRYVRSRVTNYFAYTRQGERLAHMHEIAQETRELREIRIAGSLPSRIVIVGGG 482

Query: 391  XXXXXXXXXXXXCGAQVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVDGGKYFERD 450
                        CGAQV+LMEKE ++GGNSAKATSGINGWGTR QAK+ I+DGGKYFERD
Sbjct: 483  LAGLSAAIEAASCGAQVILMEKEGRIGGNSAKATSGINGWGTRTQAKSDILDGGKYFERD 542

Query: 451  TYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHRAPDKKDGT 510
            T+ SG+GG TDPALVK LS+KS DAIGWLTSLGVPL+VLSQLGGHS KRTHRAPDK DGT
Sbjct: 543  TFLSGVGGTTDPALVKVLSVKSGDAIGWLTSLGVPLSVLSQLGGHSFKRTHRAPDKTDGT 602

Query: 511  PLPIGFTIMKTLEDHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRVTGVEF---T 567
            PLPIG TIM+TLEDH+R NLS R+TIM + SVT LL ET   PDG  ++RVTGV +   +
Sbjct: 603  PLPIGHTIMRTLEDHIRNNLSERVTIMTHVSVTELLHETDTTPDGASEVRVTGVRYRDLS 662

Query: 568  QAGSGKTTILADAVILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWATGDGVKLAQRL 627
                  + +LADAV+LATGGFSND+  +SLL ++APHL +FPTTNGPWATGDGVKLA  +
Sbjct: 663  DVDGQPSKLLADAVVLATGGFSNDREENSLLCKYAPHLASFPTTNGPWATGDGVKLATSV 722

Query: 628  GAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELDLRSVV 687
            GA+LVDMDKVQLHPTGLI+PKDPAN TK LGPEALRGSGG+LLNKQGKRFVNELDLRSVV
Sbjct: 723  GAKLVDMDKVQLHPTGLIDPKDPANTTKILGPEALRGSGGILLNKQGKRFVNELDLRSVV 782

Query: 688  SKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRDLAALI 747
            SKAI  QG EYPGSGG  FAYCVLN  A  LF   +  FY KK+GLF +A+T+ +LA LI
Sbjct: 783  SKAINTQGNEYPGSGGCYFAYCVLNEDATNLFCGGALGFYGKKLGLFQRAETVEELAKLI 842

Query: 748  GCPVESVQQTLEEYERLSTSQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLI 807
            GC    ++ TLE+YE  S ++ +CP+T K V+PCV+GT+GPY VAFVTPSIHYTMGGCLI
Sbjct: 843  GCDEGELRDTLEKYETCSKAKVACPVTGKVVFPCVVGTRGPYNVAFVTPSIHYTMGGCLI 902

Query: 808  SPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXXXXXXXXXXXXXNSLLECVVFGRIAGDR 867
            SP+AE+ ++       L +  PI  LF                 NSLLECVVFG+IAGDR
Sbjct: 903  SPAAEV-LQEYKGLNILENHRPIRCLFGAGEVTGGVHGGNRLGGNSLLECVVFGKIAGDR 961

Query: 868  ASTILQRKSSALSFKVWTTVVLREVREGGVYGAGSRVLRFNLPGALQRSGLSLGQFIAIR 927
            A+TILQ++  ALS   WT+VV+RE R G  +G GSRVLRFNLPGALQR+GL+LG+F+AIR
Sbjct: 962  AATILQKREIALSKTSWTSVVVRESRSGEQFGTGSRVLRFNLPGALQRTGLNLGEFVAIR 1021

Query: 928  GDWDGQQLIGYYSPITLPDDLGMIDILARSDKGTLREWISALEPGDAVEMKACGGLVIER 987
            G+WDGQQL+GY+SPITLP+DLG I +L R+DKGTL+EWI AL PGD+VE+KACGGL I++
Sbjct: 1022 GEWDGQQLVGYFSPITLPEDLGTISLLVRADKGTLKEWICALRPGDSVEIKACGGLRIDQ 1081

Query: 988  RLSDKHFVFMGHIINKLCLIAGGTGVAPMLQIIKAAFMKPFIDTLESVHLIYAAEDXXXX 1047
                K  +F    I +  L+A GTGVAPMLQ+I+AA  KP++DTLES+ LIYAAE+    
Sbjct: 1082 DPVKKCLLFRNRPITRFALVAAGTGVAPMLQVIRAALKKPYVDTLESIRLIYAAEEYDTL 1141

Query: 1048 XXXXXXXXXXXXXXGKFKKTFVLNRPPPLWTDGVGFIDRGILTNHVQPPSDNLLVAICGP 1107
                           KF   FVLN PP  WT GVGF+++  L   +QPPS   L+ +CGP
Sbjct: 1142 TYRSILQRFAEEFPDKFVCNFVLNNPPEGWTGGVGFVNKKSLQKVLQPPSSEPLIVVCGP 1201

Query: 1108 PVMQRIVKATLKTLGYNMNLVRTVD 1132
            PVMQR VK  L ++GY+  LV TVD
Sbjct: 1202 PVMQRDVKNELLSMGYDKELVHTVD 1226



>gi|72547207|ref|XP_843192.1| NADH-dependent fumarate reductase-like protein [Leishmania major
            strain Friedlin]
 gi|70905671|gb|AAZ14310.1| NADH-dependent fumarate reductase-like protein [Leishmania major
            strain Friedlin]
          Length = 1194

 Score = 1240 bits (3209), Expect = 0.0,   Method: Composition-based stats.
 Identities = 619/1129 (54%), Positives = 774/1129 (68%), Gaps = 48/1129 (4%)

Query: 49   TVPYALKVVASADTFDRAKEVADEVLRC----AWQLADTVLNSFNPNSEVSLVGRLPVGQ 104
            TVPY L +         A++ AD V++      + + D  LNSFNP+SEVS V R+PVG+
Sbjct: 66   TVPYTLTIAVDGSV---ARQDADPVVKAILSDCFAMVDKHLNSFNPDSEVSQVNRMPVGK 122

Query: 105  KHQMSAPLKRVMACCQRVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQAC-- 162
            KH MS  L  V+ CC+ VY+ S  CFDP+ AP+   LR+ A  ++          +    
Sbjct: 123  KHVMSEHLFEVVKCCEEVYHRSGSCFDPAAAPLVHKLRDAARRQDSTEGDFAITAEEAGR 182

Query: 163  -TLPNSFVIDFEAGTISRKHEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCR 221
             TL NSF ID + GTI+RKHE A+LDLGG++KGY VD V+D +NAA F +V F+WGGDCR
Sbjct: 183  FTLTNSFAIDIKEGTIARKHEDATLDLGGLNKGYTVDCVVDQLNAANFADVLFEWGGDCR 242

Query: 222  ASGMNARNTPWVVGITRPPSLD-----------MLRNP---------------------- 248
            ASG+N +  PW VG+ RPPS+D           M  N                       
Sbjct: 243  ASGVNVQRQPWAVGVVRPPSVDEIVAAAKSGKSMTMNAHSLGDHTDEPAPSTLAADGAAK 302

Query: 249  PKEASYISVISLDNEALATSGDYENLIYT-ADDKPLTCTYDWKAKELMKPSQSNIAQVSV 307
            P   +++ V+SL NEAL TSGDYEN+++  A    L+ TY+W+ + L++P Q+ +AQVS+
Sbjct: 303  PAHKAFLRVMSLSNEALCTSGDYENVLFANALGCALSSTYNWRRRCLIEPCQNELAQVSI 362

Query: 308  KCYSAMYADALATACFIKRDPAKVRQLLDGWXXXXXXXXXXXXXXXENERVAKMFEIATE 367
            KCYS +YADALATA F+KRDP +VR +L+ +               E ER+A M+EIA E
Sbjct: 363  KCYSCLYADALATASFVKRDPVRVRYMLEPYRHDYNRVTDYAAYTREGERLAHMYEIAHE 422

Query: 368  DAEMRKRRISNTLPARVIVVXXXXXXXXXXXXXXXCGAQVVLMEKEAKLGGNSAKATSGI 427
                R  RI+ +LPARV+V+               CGA V+L+EKEA+LGGNSAKATSGI
Sbjct: 423  SPACRIERIAGSLPARVVVIGGGLAGCAAAIEAASCGATVILLEKEARLGGNSAKATSGI 482

Query: 428  NGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLT 487
            NGWGTR QA   ++D  K+FERDT+ SG GG+ DP LV+TLS+KSA+AI WL S G+PLT
Sbjct: 483  NGWGTRTQAVNHVLDNCKFFERDTFLSGKGGHCDPGLVRTLSVKSAEAISWLESFGIPLT 542

Query: 488  VLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENCSVTSLLS 547
            VL QLGG SR+R HRAPD+KDGTP+P+GFTIM+ LEDH+R  L G++TI+   +V SL+ 
Sbjct: 543  VLYQLGGASRRRCHRAPDQKDGTPVPVGFTIMRHLEDHIRTKLQGKVTILNEMAVVSLMH 602

Query: 548  ETKERPDGTKQIRVTGVEFTQAGSGKTTIL---ADAVILATGGFSNDKTADSLLREHAPH 604
            +    PDG ++IRV GV +T       T++   ADAV+LATGGFSND+T +SLLRE+AP+
Sbjct: 603  DVSAMPDGNREIRVHGVRYTSMTDASGTVMDLPADAVVLATGGFSNDRTPNSLLREYAPN 662

Query: 605  LVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRG 664
            +   PTTNG +ATGDGVK+A++LGA LVDMDKVQLHPTGLI+PKDP+N TK+LGPEALRG
Sbjct: 663  VYGTPTTNGTFATGDGVKMARKLGATLVDMDKVQLHPTGLIDPKDPSNRTKYLGPEALRG 722

Query: 665  SGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSH 724
            SGG+LLNK G+RFVNELDLRSVVS+AI+ Q  EYP SGGS FAYCVLN  A  LFG +S 
Sbjct: 723  SGGILLNKNGERFVNELDLRSVVSQAIIAQDNEYPNSGGSKFAYCVLNEEAATLFGKNSL 782

Query: 725  EFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYPCVLG 784
             +YWK  GLF + D M+ LA LIGC VES+ +TLE YER ST +++CP+T K V+P V+G
Sbjct: 783  TYYWKSQGLFTRVDDMKALAELIGCSVESLHRTLETYERQSTGKKACPLTGKLVFPSVVG 842

Query: 785  TKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXXXXXX 844
            TKGPYYVA+VTPSIHYTMGGC ISP+AE+ M++ S         PILGLF          
Sbjct: 843  TKGPYYVAYVTPSIHYTMGGCFISPAAELLMEDHSVNI-FDDMRPILGLFGAGEVTGGVH 901

Query: 845  XXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGAGSRV 904
                   NSLLECVVFG+IAGDRA+TILQ++   LS   W  VV+RE R    +G GSRV
Sbjct: 902  GRNRLGGNSLLECVVFGKIAGDRAATILQKEKHGLSKDKWVPVVVRESRASDQFGVGSRV 961

Query: 905  LRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKGTLRE 964
            LRFNLPGA Q SGL++G+FI IRGDWDGQQLIGYYSPI +PDD G I ILAR DKG L+E
Sbjct: 962  LRFNLPGATQTSGLTVGEFIGIRGDWDGQQLIGYYSPINMPDDKGRISILARGDKGNLQE 1021

Query: 965  WISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQIIKAAF 1024
            WIS++ PGD+VEMKACGGL IE +   K  V+   +I KL LIAGG+GVAPMLQIIKAA 
Sbjct: 1022 WISSMRPGDSVEMKACGGLRIELKPHQKQMVYRKTVIRKLGLIAGGSGVAPMLQIIKAAL 1081

Query: 1025 MKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXGKFKKTFVLNRPPPLWTDGVGFI 1084
             +P++D++E++ L+YAAED                  GKF   FVLN PP  WT+GVG++
Sbjct: 1082 NRPYVDSIETIRLVYAAEDEYELTYRLLLKQYRTDNPGKFDCGFVLNNPPEGWTEGVGYV 1141

Query: 1085 DRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDE 1133
            DR  L + + PPS  LLVAICGPPVMQR V A L  LGYN  +VRTVDE
Sbjct: 1142 DRATLQSLLPPPSKGLLVAICGPPVMQRSVVADLLALGYNAEMVRTVDE 1190



>gi|146100590|ref|XP_001468899.1| NADH-dependent fumarate reductase-like protein [Leishmania infantum]
 gi|134073268|emb|CAM71992.1| NADH-dependent fumarate reductase-like protein [Leishmania infantum]
          Length = 1194

 Score = 1221 bits (3160), Expect = 0.0,   Method: Composition-based stats.
 Identities = 612/1129 (54%), Positives = 767/1129 (67%), Gaps = 48/1129 (4%)

Query: 49   TVPYALKVVASADTFDRAKEVADEVLRC----AWQLADTVLNSFNPNSEVSLVGRLPVGQ 104
            TVPY L +    +    A++  D V++      + + D  LNSFNP SEVS V R+PVG+
Sbjct: 66   TVPYTLTIAVDGNV---ARQDVDPVVKAILSDCFAMVDKHLNSFNPGSEVSQVNRMPVGK 122

Query: 105  KHQMSAPLKRVMACCQRVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQAC-- 162
            KH MS  L  V+ CC+ VY+SS  CFDP+ AP+   LR+ A  ++          +    
Sbjct: 123  KHVMSEHLFEVVKCCEEVYSSSGSCFDPAAAPLVHKLRDAARRQDSAEGDFAISAEEAGR 182

Query: 163  -TLPNSFVIDFEAGTISRKHEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCR 221
             TL NSF ID + GTI+RKHE A LDLGG++KGY VD V+D +NAA F +V F+WGGDCR
Sbjct: 183  FTLTNSFAIDIKEGTIARKHEDAMLDLGGLNKGYTVDCVVDRLNAANFADVLFEWGGDCR 242

Query: 222  ASGMNARNTPWVVGITRPPSLDMLRNPPKEASYIS------------------------- 256
            ASG+N +  PW VG+ RPPS+D +    K    ++                         
Sbjct: 243  ASGVNVQRQPWAVGVVRPPSVDEVVAAAKSGKSVTMNAHSLGDHTDEPAQSTSAADGAAK 302

Query: 257  --------VISLDNEALATSGDYENLIYT-ADDKPLTCTYDWKAKELMKPSQSNIAQVSV 307
                    V+SL NEAL TSGDYEN+++  A    L+ TYDW+ + L++P ++ +AQVS+
Sbjct: 303  AEHKALLRVMSLSNEALCTSGDYENVLFANALGCALSSTYDWRRRCLIEPCRNELAQVSI 362

Query: 308  KCYSAMYADALATACFIKRDPAKVRQLLDGWXXXXXXXXXXXXXXXENERVAKMFEIATE 367
            KCYS +YADALATA F+KRDP +VR +L+ +               E ER+A M+EIA E
Sbjct: 363  KCYSCLYADALATASFVKRDPVRVRYMLEHYRHDYNRVTDYAAYTREGERLAHMYEIAHE 422

Query: 368  DAEMRKRRISNTLPARVIVVXXXXXXXXXXXXXXXCGAQVVLMEKEAKLGGNSAKATSGI 427
                R  RI+ +LPARV+V+               CGA V+L+EKEA+LGGNSAKATSGI
Sbjct: 423  SPACRIERIAGSLPARVVVIGGGLAGCAAAIEAASCGATVILLEKEARLGGNSAKATSGI 482

Query: 428  NGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLT 487
            NGWGTR QA   ++D  K+FERDT+ SG GG+ DP LV+TLS+KSA+AI WL S G+PLT
Sbjct: 483  NGWGTRTQAVNHVLDNCKFFERDTFLSGKGGHCDPGLVRTLSVKSAEAISWLESFGIPLT 542

Query: 488  VLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENCSVTSLLS 547
            VL QLGG SR+R HRAPD+KDGTP+P+GFTIM+ LED++R  L G++TI+   +V SL+ 
Sbjct: 543  VLYQLGGASRRRCHRAPDQKDGTPVPVGFTIMRHLEDYIRTKLQGKVTILNEMAVVSLMH 602

Query: 548  ETKERPDGTKQIRVTGVEFTQAGSGKTTIL---ADAVILATGGFSNDKTADSLLREHAPH 604
            +    PDG ++IRV GV +        T++   ADAV+LATGGFSND T +SLLRE+AP+
Sbjct: 603  DVSAMPDGNREIRVHGVRYKSMTDASGTVMDLPADAVVLATGGFSNDHTPNSLLREYAPN 662

Query: 605  LVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRG 664
            +   PTTNG +ATGDGVK+A++LGA LVDMDKVQLHPTGLI+PKDP+N TK+LGPEALRG
Sbjct: 663  VYGTPTTNGTFATGDGVKMARKLGATLVDMDKVQLHPTGLIDPKDPSNRTKYLGPEALRG 722

Query: 665  SGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSH 724
            SGG+LLNK G+RFVNELDLRSVVS+AI+ Q  EYP SGGS FAYCVL+  A  LFG +S 
Sbjct: 723  SGGILLNKNGERFVNELDLRSVVSQAIIAQDNEYPNSGGSKFAYCVLSEEAATLFGKNSL 782

Query: 725  EFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYPCVLG 784
             +YWK  GLF + D M+ LA LIGC VES+ +TLE YER ST +++CP T K V+P V+G
Sbjct: 783  TYYWKSQGLFTRVDDMKALAELIGCSVESLHRTLETYERQSTGKKACPRTGKLVFPSVVG 842

Query: 785  TKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXXXXXX 844
            TKGPYYVA+VTPSIHYTMGGC ISP+AE+ M++ S        +PILGLF          
Sbjct: 843  TKGPYYVAYVTPSIHYTMGGCFISPAAELLMEDHSVNI-FEDMHPILGLFGAGEVTGGVH 901

Query: 845  XXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGAGSRV 904
                   NSLLECVVFG+IAGDRA+TILQ++   L    W  VV+RE R    +G GSRV
Sbjct: 902  GRNRLGGNSLLECVVFGKIAGDRAATILQKEKHGLRKDKWVPVVVRESRASDQFGVGSRV 961

Query: 905  LRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKGTLRE 964
            LRFNLPGA Q SGL++G+FI IRGDWDGQQLIGYYSPI +PDD G I ILAR DKG L+E
Sbjct: 962  LRFNLPGATQTSGLTVGEFIGIRGDWDGQQLIGYYSPINMPDDKGRISILARGDKGNLQE 1021

Query: 965  WISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQIIKAAF 1024
            WIS++ PGD+VEMKACGGL IE +   K  V+   +I KL LIAGG+GVAPMLQIIKAA 
Sbjct: 1022 WISSMRPGDSVEMKACGGLRIELKPHQKQMVYRKTVIRKLGLIAGGSGVAPMLQIIKAAL 1081

Query: 1025 MKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXGKFKKTFVLNRPPPLWTDGVGFI 1084
             +P++D++E++ L+YAAED                   KF   FVLN PP  WT+GVG++
Sbjct: 1082 NRPYVDSIETIRLVYAAEDEYELTYRSLLKQYRADNPDKFDCGFVLNNPPEGWTEGVGYV 1141

Query: 1085 DRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDE 1133
            DR  L + + PPS  LLVAICGPPVMQR V A L  LGYN  +VRTVDE
Sbjct: 1142 DRATLQSLLPPPSKGLLVAICGPPVMQRSVVADLLALGYNAEMVRTVDE 1190



>gi|154344505|ref|XP_001568194.1| NADH-dependent fumarate reductase-like protein [Leishmania
            braziliensis MHOM/BR/75/M2904]
 gi|134065531|emb|CAM43299.1| NADH-dependent fumarate reductase-like protein [Leishmania
            braziliensis]
          Length = 1194

 Score = 1202 bits (3109), Expect = 0.0,   Method: Composition-based stats.
 Identities = 600/1126 (53%), Positives = 765/1126 (67%), Gaps = 42/1126 (3%)

Query: 49   TVPYALKV-VASADTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQ 107
            TVPY L + V  + T   A  V   +L   + + DT LNSFNP+SEVS V R+PVG+KH 
Sbjct: 66   TVPYTLSIAVDGSVTRQDADPVVKAILSNCFTMVDTHLNSFNPDSEVSKVNRMPVGEKHV 125

Query: 108  MSAPLKRVMACCQRVYNSSAGCFDPSTAPVAKALREIALGKERNNACLEALTQAC---TL 164
            MS  L +V+ CC+ +YN S  CFDP+ AP+   LR  A  ++   A      +     TL
Sbjct: 126  MSEHLCKVVKCCEEIYNISGSCFDPAAAPLVHRLRNAARRQDSTEADFMITAEVAGRFTL 185

Query: 165  PNSFVIDFEAGTISRKHEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASG 224
             NSF I+ + GTI+RKHE A LDLGG++KGY VD V+D +NAA F +V F+WGGDCRASG
Sbjct: 186  TNSFAINVKEGTIARKHEDAMLDLGGLNKGYTVDCVVDQLNAANFSDVLFEWGGDCRASG 245

Query: 225  MNARNTPWVVGITRPPSLDML---------------------RNPPKEAS---------- 253
            +N +  PW VG+ RPPS+D +                       P + AS          
Sbjct: 246  VNVQRQPWAVGVVRPPSVDEVVAASKSGKSVTMNAHSLGERSDEPAQSASAADGAAKPGH 305

Query: 254  --YISVISLDNEALATSGDYENLIYT-ADDKPLTCTYDWKAKELMKPSQSNIAQVSVKCY 310
               + V+SL NEAL TSGDYEN+++  A ++ ++ TYDW+ + L+ PSQ  +AQVSVKCY
Sbjct: 306  KTLLRVMSLSNEALCTSGDYENVLFVNALNRAVSSTYDWRHRCLIGPSQGGLAQVSVKCY 365

Query: 311  SAMYADALATACFIKRDPAKVRQLLDGWXXXXXXXXXXXXXXXENERVAKMFEIATEDAE 370
            S +YADALATA F+KR+P  +R +L+ +               E ER+A M+EIA E   
Sbjct: 366  SCLYADALATASFVKRNPVPIRYMLEHYRRDYNRVTDYTAYTREGERLAHMYEIACESPA 425

Query: 371  MRKRRISNTLPARVIVVXXXXXXXXXXXXXXXCGAQVVLMEKEAKLGGNSAKATSGINGW 430
             R  RI+ +LPARV+V+               CGA V+L+EKEA+LGGNSAKATSGIN W
Sbjct: 426  CRTERIAGSLPARVVVIGGGLAGCAAAIEAASCGATVILLEKEARLGGNSAKATSGINAW 485

Query: 431  GTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLTVLS 490
            GTR QA   ++D  K+FERDT+ SG GG+ DP LV+TLS+KSA+AI WL S G+PLT L 
Sbjct: 486  GTRTQAVNHVLDNCKFFERDTFLSGKGGHCDPGLVRTLSVKSAEAISWLESFGIPLTALY 545

Query: 491  QLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENCSVTSLLSETK 550
            QLGG SR R HRAPD+KDG+P+PIGFTIM+ LE+++   L G++TI+   +V SLL +  
Sbjct: 546  QLGGASRPRCHRAPDQKDGSPVPIGFTIMRHLENYIHTKLQGKVTILCETAVVSLLHDVS 605

Query: 551  ERPDGTKQIRVTGVEFTQAGSGKTTIL---ADAVILATGGFSNDKTADSLLREHAPHLVN 607
              PDG+++IRV GV +         ++   ADAV+LATGGFSND+T +SLLRE+AP++  
Sbjct: 606  AMPDGSREIRVRGVRYKSTSDASEAVIDLPADAVVLATGGFSNDQTVNSLLREYAPNVYG 665

Query: 608  FPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRGSGG 667
             PTTNG +ATGDGVK+A++LGA+LVDMDKVQLHPTGLI+PKDP+N TK+LGPEALRGSGG
Sbjct: 666  TPTTNGAFATGDGVKMARQLGARLVDMDKVQLHPTGLIDPKDPSNRTKYLGPEALRGSGG 725

Query: 668  VLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSHEFY 727
            +LLN+ G+RFVNELDLRSVVS+AI  Q  EYP SGGS FAYCVL+  A KLFG ++  +Y
Sbjct: 726  ILLNRNGERFVNELDLRSVVSQAINAQDDEYPNSGGSKFAYCVLSEEAAKLFGKNALTYY 785

Query: 728  WKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYPCVLGTKG 787
            WK  GLF + D ++ LA LIGC V+++ +TLE YE  ST++ +CP+T K V+P V+GT G
Sbjct: 786  WKSQGLFTRVDNIKALAELIGCSVDNLHRTLETYEHQSTAKVACPLTGKLVFPSVVGTSG 845

Query: 788  PYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXXXXXXXXX 847
            PYYVA+VTPSIHYTMGGC ISP+AE+ M++ S         PILGLF             
Sbjct: 846  PYYVAYVTPSIHYTMGGCSISPAAELLMEDHSVNI-FEDMRPILGLFGAGEVTGGVHGRN 904

Query: 848  XXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGAGSRVLRF 907
                NSLLECVVFG+IAGDRA+TILQ++   LS   W  VV+RE R    +G GSRVL F
Sbjct: 905  RLGGNSLLECVVFGKIAGDRAATILQKEKYGLSKDKWVPVVVRETRASDQFGVGSRVLHF 964

Query: 908  NLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARSDKGTLREWIS 967
            NLPGA Q SGL++G+FI+IRGDWDGQ LIGYYSPI++PDD G I ILAR DKG L+EW+S
Sbjct: 965  NLPGATQTSGLTVGEFISIRGDWDGQHLIGYYSPISMPDDKGRISILARGDKGNLQEWVS 1024

Query: 968  ALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQIIKAAFMKP 1027
            ++ PGD+VEMKACGGL IE +   K  ++   +I KL LIAGG+GVAPMLQIIKAA  +P
Sbjct: 1025 SMRPGDSVEMKACGGLRIELKPQQKQMIYRKTVIRKLALIAGGSGVAPMLQIIKAALSRP 1084

Query: 1028 FIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXGKFKKTFVLNRPPPLWTDGVGFIDRG 1087
            ++D++E++ L+YAAED                   KF   FVLN PP  WT+GVG++DR 
Sbjct: 1085 YVDSIETIRLVYAAEDEYELTYRSLLKKYRTDNTEKFDCDFVLNNPPEGWTEGVGYVDRA 1144

Query: 1088 ILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDE 1133
             L + + PPS  LLVAICGPPVMQ  V A L  LGY+   VRT+DE
Sbjct: 1145 TLQSFLPPPSKGLLVAICGPPVMQHSVVADLLALGYSAETVRTIDE 1190



>gi|72388946|ref|XP_844768.1| NADH-dependent fumarate reductase, putative [Trypanosoma brucei
            TREU927]
 gi|62176059|gb|AAX70180.1| NADH-dependent fumarate reductase, putative [Trypanosoma brucei]
 gi|70801302|gb|AAZ11209.1| NADH-dependent fumarate reductase, putative [Trypanosoma brucei]
          Length = 877

 Score =  998 bits (2581), Expect = 0.0,   Method: Composition-based stats.
 Identities = 520/708 (73%), Positives = 559/708 (78%), Gaps = 23/708 (3%)

Query: 383  RVIVVXXXXXXXXXXXXXXXCGAQVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVD 442
            RVIVV               CGAQVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVD
Sbjct: 145  RVIVVGGGLAGLSAAIEAAGCGAQVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVD 204

Query: 443  GGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHR 502
            GGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHR
Sbjct: 205  GGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHR 264

Query: 503  APDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRVT 562
            APDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRVT
Sbjct: 265  APDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRVT 324

Query: 563  GVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWATGDGVK 622
            GVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWATGDGVK
Sbjct: 325  GVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWATGDGVK 384

Query: 623  LAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELD 682
            LAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELD
Sbjct: 385  LAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELD 444

Query: 683  LRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRD 742
            LRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRD
Sbjct: 445  LRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRD 504

Query: 743  LAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTM 802
            LAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTM
Sbjct: 505  LAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTM 564

Query: 803  GGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXXXXXXXXXXXXXNSLLECVVFGR 862
            GGCLISPSAEIQMKNTSSRAPLSHSNPILGLF                 NSLLECVVFGR
Sbjct: 565  GGCLISPSAEIQMKNTSSRAPLSHSNPILGLFGAGEVTGGVHGGNRLGGNSLLECVVFGR 624

Query: 863  IAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGAGSRVLRFNLPGALQRSGLSLGQ 922
            IAG  A+       + L    W  +V+  V +      G + L F LP  LQRSG+   Q
Sbjct: 625  IAGASAANAKYHNETHLWNNRWAKMVVESVLDD---TNGYQWLYFRLPSTLQRSGVGPLQ 681

Query: 923  FIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARS-DKGTLREWISALEPGDAVEMKACG 981
             + +R + +G+  +    P T+P D+G++ I+  S D+ +   W++AL PG  VEMKA  
Sbjct: 682  AVVLR-EMEGEGRLDVRIPFTVPGDVGVVGIMVYSNDENSSMGWLTALLPGGMVEMKA-- 738

Query: 982  GLVI----ERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQIIKAAFMKPFIDTLESVHL 1037
            G+ +    ER L+          + +  +IA   GVAPM+Q+I+AA  +       ++ +
Sbjct: 739  GVQVDANYERILA----------LPRKVIIATRDGVAPMVQMIRAALHEA--KDEPALQI 786

Query: 1038 IYAAEDXXXXXXXXXXXXXXXXXXGKFKKTFVLNRPPPLWTDGVGFID 1085
            IY AE                    KFK TFV++ PPPLWT GV  ++
Sbjct: 787  IYIAERVATIPQREKLEQLQRDHPNKFKFTFVVHDPPPLWTGGVNIME 834



>gi|60460039|gb|AAX20164.1| mitochondrial NADH-dependent fumarate reductase [Trypanosoma brucei]
          Length = 877

 Score =  992 bits (2564), Expect = 0.0,   Method: Composition-based stats.
 Identities = 517/708 (73%), Positives = 557/708 (78%), Gaps = 23/708 (3%)

Query: 383  RVIVVXXXXXXXXXXXXXXXCGAQVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVD 442
            RVIVV               CGAQVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVD
Sbjct: 145  RVIVVGGGLAGLSAAIEAAGCGAQVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVD 204

Query: 443  GGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHR 502
            GGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHR
Sbjct: 205  GGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHR 264

Query: 503  APDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRVT 562
            APDKKDGTPLPIGF I+KTLEDHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRVT
Sbjct: 265  APDKKDGTPLPIGFAIVKTLEDHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRVT 324

Query: 563  GVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWATGDGVK 622
            GVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWATGDGVK
Sbjct: 325  GVEFTQAGSGKTTILADAVILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWATGDGVK 384

Query: 623  LAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELD 682
            LAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELD
Sbjct: 385  LAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELD 444

Query: 683  LRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRD 742
            LRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRD
Sbjct: 445  LRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRD 504

Query: 743  LAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTM 802
            LAALIGCPVESVQQTLEEYERLS SQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTM
Sbjct: 505  LAALIGCPVESVQQTLEEYERLSISQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTM 564

Query: 803  GGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXXXXXXXXXXXXXNSLLECVVFGR 862
            GGCLISPSAEIQMKNTSSRAPLSHSNPILGLF                 NSLLECVVFGR
Sbjct: 565  GGCLISPSAEIQMKNTSSRAPLSHSNPILGLFGAGEVTGGVHGGNRLGGNSLLECVVFGR 624

Query: 863  IAGDRASTILQRKSSALSFKVWTTVVLREVREGGVYGAGSRVLRFNLPGALQRSGLSLGQ 922
            IAG  A+       + L    W  +V+  V +      G + L F LP  LQRSG+   Q
Sbjct: 625  IAGASAANAKYHNETHLWNNRWAKMVVESVLDD---TNGFQWLYFRLPSTLQRSGVGPLQ 681

Query: 923  FIAIRGDWDGQQLIGYYSPITLPDDLGMIDILARS-DKGTLREWISALEPGDAVEMKACG 981
             + +R + +G+  +    P T+P D+G++ I+  S D+ +   W++AL PG  VEMKA  
Sbjct: 682  AVVLR-EMEGEGRLDVRIPFTVPGDVGVVGIMVYSNDENSSMGWLTALLPGGMVEMKA-- 738

Query: 982  GLVI----ERRLSDKHFVFMGHIINKLCLIAGGTGVAPMLQIIKAAFMKPFIDTLESVHL 1037
            G+ +    ER L+          + +  +IA   GVAPM+Q+I+AA  +       ++ +
Sbjct: 739  GVQVDANYERILA----------LPRKVIIATRDGVAPMVQMIRAALHEA--KDEPALQI 786

Query: 1038 IYAAEDXXXXXXXXXXXXXXXXXXGKFKKTFVLNRPPPLWTDGVGFID 1085
            IY AE                    KFK TFV++ PPPLWT GV  ++
Sbjct: 787  IYIAERVATIPQREKLEQLQRDHPNKFKFTFVVHDPPPLWTGGVNIME 834



>gi|71416397|ref|XP_810232.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi strain
            CL Brener]
 gi|70874733|gb|EAN88381.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi]
          Length = 789

 Score =  824 bits (2128), Expect = 0.0,   Method: Composition-based stats.
 Identities = 435/778 (55%), Positives = 538/778 (69%), Gaps = 25/778 (3%)

Query: 362  FEIATEDAEMRKRRISNTLPAR------VIVVXXXXXXXXXXXXXXXCGAQVVLMEKEAK 415
            F + TE   M+ +R     PA       VIVV               CGAQV+L+EKE +
Sbjct: 30   FTLMTEQMNMQPQRDVFYDPAELQKQPVVIVVGGGLAGLSAAIEATACGAQVILLEKEPR 89

Query: 416  LGGNSAKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADA 475
            +GGNSAKATSGINGWGTRAQA+  + D GKYFERDT+KSG+GG+TDP LV+TLS+KS DA
Sbjct: 90   VGGNSAKATSGINGWGTRAQAEQDVYDSGKYFERDTHKSGLGGSTDPGLVRTLSVKSGDA 149

Query: 476  IGWLTSLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRIT 535
            I WL+SLGVPLTVLSQLGGHSRKRTHRAPDK DGTP+PIGFTIM+TLE H+R  L+ R+T
Sbjct: 150  ISWLSSLGVPLTVLSQLGGHSRKRTHRAPDKADGTPVPIGFTIMQTLEQHIRTKLTDRVT 209

Query: 536  IMENCSVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGGFSNDKTAD 595
            IMEN +VTSLLS+++ R DG KQ+RV GVE  Q     + ILADAVILATGGFSNDKT +
Sbjct: 210  IMENTTVTSLLSKSRVRHDGAKQVRVYGVEVLQDEGVASRILADAVILATGGFSNDKTPN 269

Query: 596  SLLREHAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTK 655
            SLL+E AP L  FPTTNGPWATGDGVKLA+ LG +LVDMDKVQLHPTGLI+PKDPANPTK
Sbjct: 270  SLLQEFAPQLSGFPTTNGPWATGDGVKLARELGVKLVDMDKVQLHPTGLIDPKDPANPTK 329

Query: 656  FLGPEALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAA 715
            +LGPEALRGSGGVLLNK+G+RFVNELDLRSVVS AI+EQG EYP SGGS FA+CVLN AA
Sbjct: 330  YLGPEALRGSGGVLLNKKGERFVNELDLRSVVSNAIIEQGDEYPDSGGSKFAFCVLNDAA 389

Query: 716  QKLFGVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITR 775
             +LFGV+SH FYWK+ GLFVKADT+ +LAALIGCPVE+V+ TL +YE+LS   R CP TR
Sbjct: 390  VRLFGVNSHGFYWKRRGLFVKADTVEELAALIGCPVENVRNTLGDYEQLSKENRQCPKTR 449

Query: 776  KSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFX 835
            K VYPCV+G +GP+YVAFVTPSIHYTMGGCLISPSAE+Q++  ++ +P  H  PI GLF 
Sbjct: 450  KVVYPCVVGPQGPFYVAFVTPSIHYTMGGCLISPSAEMQLEENTT-SPFGHRRPIFGLFG 508

Query: 836  XXXXXXXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREG 895
                            NSLLECVVFGRIAGDRA+TILQ   + L  + W+ + LR V E 
Sbjct: 509  AGEVTGGVHGGNRLGGNSLLECVVFGRIAGDRAATILQNNDTYLWGEKWSQLKLRNVVE- 567

Query: 896  GVYGAGSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDI-L 954
                 G   L F  P + Q SGL + Q + +R    G + +  Y+P TLPDD G++ I L
Sbjct: 568  --EENGFMWLHFTFPSSFQVSGLEVLQGVVLR-SVSGDKSVEVYTPYTLPDDEGVVGIAL 624

Query: 955  ARSDKGTLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVA 1014
            +    G    W+  L+PGD VEMKA      ER   D+ ++ M +  +K+ +IA   G+A
Sbjct: 625  SPLLTGNGVHWLRTLQPGDTVEMKAA-----ER--VDRGYMNMLNAPHKV-VIATSRGIA 676

Query: 1015 PMLQIIKAAFMKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXGKFKKTFVLNRPP 1074
            PM+QI++AA   P  DT  ++HLIY A+                    +F+ TFVL  P 
Sbjct: 677  PMMQILRAAMEGPEKDT--TIHLIYIADRASSIPHREKLKALAEASPERFRCTFVLQHPQ 734

Query: 1075 PLWTDGVGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVD 1132
            P W+  V ++D    +     P   L++ +CG     R +K++L  +G+++  + TV+
Sbjct: 735  PGWSGAVNYVDEVAASVF---PDPALVIFLCGASEETRSIKSSLLDMGHDVATIATVE 789



>gi|71403387|ref|XP_804499.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi
           strain CL Brener]
 gi|70867504|gb|EAN82648.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi]
          Length = 588

 Score =  758 bits (1956), Expect = 0.0,   Method: Composition-based stats.
 Identities = 369/588 (62%), Positives = 446/588 (75%), Gaps = 1/588 (0%)

Query: 1   MVDGRSSASIXXXXXXXXXXXXXXXXXXLLQDSPLHTTMQYATSGLELTVPYALKVVASA 60
           M DGRSSAS+                  LL+DSPL T +QY T+GLELTVP+ LKVVA A
Sbjct: 1   MADGRSSASVVAVDPEKAARERDEAARALLRDSPLQTHLQYMTNGLELTVPFTLKVVAEA 60

Query: 61  DTFDRAKEVADEVLRCAWQLADTVLNSFNPNSEVSLVGRLPVGQKHQMSAPLKRVMACCQ 120
             F RAKEVADEVLR AW LADTVLN+FNPNSE+S++GRLPVGQKH MSA LK V+ CCQ
Sbjct: 61  VAFSRAKEVADEVLRSAWHLADTVLNNFNPNSEISMIGRLPVGQKHTMSATLKSVITCCQ 120

Query: 121 RVYNSSAGCFDPSTAPVAKALR-EIALGKERNNACLEALTQACTLPNSFVIDFEAGTISR 179
            V+NSS G FDP+T P+ +ALR ++A     ++  +E L + C  P+SF +D E GTI+R
Sbjct: 121 HVFNSSRGVFDPATGPIIEALRAKVAEKASVSDEQMEKLFRVCNFPSSFSVDLEMGTIAR 180

Query: 180 KHEHASLDLGGVSKGYIVDYVIDNINAAGFQNVFFDWGGDCRASGMNARNTPWVVGITRP 239
           KHE A  DLGGVSKGYIVDYV++ +NAAG  +V+F+WGGDCRASG NAR TPW+VGI RP
Sbjct: 181 KHEDARFDLGGVSKGYIVDYVVERLNAAGIVDVYFEWGGDCRASGTNARRTPWMVGIIRP 240

Query: 240 PSLDMLRNPPKEASYISVISLDNEALATSGDYENLIYTADDKPLTCTYDWKAKELMKPSQ 299
           PS++ LRNPPK+ SYI V+ L++EAL TSGDYENL   ++ K  T  +DWK K+L++P +
Sbjct: 241 PSMEQLRNPPKDPSYIRVLPLNDEALCTSGDYENLTEGSNKKLYTSIFDWKKKDLLEPVE 300

Query: 300 SNIAQVSVKCYSAMYADALATACFIKRDPAKVRQLLDGWXXXXXXXXXXXXXXXENERVA 359
           S +AQVS+KCYSAMYADALATA  IKRD  KVRQ+L+ W               + ERVA
Sbjct: 301 SELAQVSIKCYSAMYADALATASLIKRDIKKVRQMLEEWRHVRNRVTNYVTYTRQGERVA 360

Query: 360 KMFEIATEDAEMRKRRISNTLPARVIVVXXXXXXXXXXXXXXXCGAQVVLMEKEAKLGGN 419
           +MFEIAT++AE+RK+RI+ +LPARVIVV               CGAQV+L+EKE ++GGN
Sbjct: 361 RMFEIATDNAEIRKKRIAGSLPARVIVVGGGLAGLSAAIEATACGAQVILLEKEPRVGGN 420

Query: 420 SAKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWL 479
           SAKATSGINGWGTRAQA+  + D GKYFERDT+KSG+GG+TDP LV+TLS+KS DAI WL
Sbjct: 421 SAKATSGINGWGTRAQAEQDVYDSGKYFERDTHKSGLGGSTDPGLVRTLSVKSGDAISWL 480

Query: 480 TSLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMEN 539
           +SLGVPLTVLSQLGGHSRKRTHRAPDK DGTP+PIGFTIM+TLE HVR  L+ R+TIMEN
Sbjct: 481 SSLGVPLTVLSQLGGHSRKRTHRAPDKADGTPVPIGFTIMQTLEQHVRTKLADRVTIMEN 540

Query: 540 CSVTSLLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAVILATGG 587
            +VTSLLS+++ R DG KQ+RV GVE  Q     + ILADAVILATGG
Sbjct: 541 TTVTSLLSKSRVRHDGAKQVRVYGVEVLQDEGVASRILADAVILATGG 588



>gi|71416399|ref|XP_810233.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi strain
            CL Brener]
 gi|70874734|gb|EAN88382.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi]
          Length = 485

 Score =  725 bits (1872), Expect = 0.0,   Method: Composition-based stats.
 Identities = 343/486 (70%), Positives = 394/486 (81%), Gaps = 1/486 (0%)

Query: 657  LGPEALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQ 716
            LGPEALRGSGGVLLNK+G+RFVNELDLRSVVS AI+EQG EYP SGGS FA+CVLN AA 
Sbjct: 1    LGPEALRGSGGVLLNKKGERFVNELDLRSVVSNAIIEQGDEYPDSGGSKFAFCVLNDAAV 60

Query: 717  KLFGVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITRK 776
            +LFGV+SH FYW ++GLFVKADT+  LAALIGCPVE+V+ TL +YE+LS   R CP TRK
Sbjct: 61   RLFGVNSHGFYWNRLGLFVKADTVEKLAALIGCPVENVRNTLGDYEQLSKENRQCPKTRK 120

Query: 777  SVYPCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXX 836
             VYPCV+G +GP+YVAFVTPSIHYTMGGCLISPSAE+Q++  ++ +P  H  PI GLF  
Sbjct: 121  IVYPCVVGPQGPFYVAFVTPSIHYTMGGCLISPSAEMQLEENTT-SPFGHRRPIFGLFGA 179

Query: 837  XXXXXXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWTTVVLREVREGG 896
                           NSLLECVVFGRIAGDRA+TILQ+K   LSFK WTTV+LREVREGG
Sbjct: 180  GEVTGGVHGGNRLGGNSLLECVVFGRIAGDRAATILQKKPVPLSFKTWTTVILREVREGG 239

Query: 897  VYGAGSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLPDDLGMIDILAR 956
            +YG GSRVLRFNLPGALQRSGL LGQFIAIRG+WDGQQLIGYYSPITLPDDLG+I ILAR
Sbjct: 240  MYGTGSRVLRFNLPGALQRSGLQLGQFIAIRGEWDGQQLIGYYSPITLPDDLGVIGILAR 299

Query: 957  SDKGTLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKLCLIAGGTGVAPM 1016
            SDKGTL+EWISALEPGDAVEMK CGGLVIERR S+++  F GH + KLCLIAGGTGVAPM
Sbjct: 300  SDKGTLKEWISALEPGDAVEMKGCGGLVIERRFSERYLYFSGHALKKLCLIAGGTGVAPM 359

Query: 1017 LQIIKAAFMKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXGKFKKTFVLNRPPPL 1076
            LQII+AA  KPF++ +ES+ LIYAAED                  GKF+  FVLNRPPP+
Sbjct: 360  LQIIRAALKKPFLENIESICLIYAAEDVSELTYRELLEQHQRDSKGKFRSIFVLNRPPPV 419

Query: 1077 WTDGVGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYNMNLVRTVDETEP 1136
            WTDGVGFID+ +L++ VQPP+ +LLVAICGPP+MQR+VK  LK+LGY+M LVRTVDE E 
Sbjct: 420  WTDGVGFIDKKLLSSSVQPPAKDLLVAICGPPIMQRVVKTCLKSLGYDMQLVRTVDEVET 479

Query: 1137 SGSSKI 1142
              SSK+
Sbjct: 480  QNSSKM 485



>gi|154344557|ref|XP_001568220.1| NADH-dependent fumarate reductase, putative [Leishmania
           braziliensis MHOM/BR/75/M2904]
 gi|134065557|emb|CAM43327.1| NADH-dependent fumarate reductase, putative [Leishmania
           braziliensis]
          Length = 514

 Score =  548 bits (1412), Expect = e-154,   Method: Composition-based stats.
 Identities = 295/503 (58%), Positives = 361/503 (71%), Gaps = 13/503 (2%)

Query: 383 RVIVVXXXXXXXXXXXXXXXCGA-QVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIV 441
           RV+V+                GA +VV++EKE +LGGNSAKATSGIN WGT  Q  A + 
Sbjct: 10  RVVVIGSGLAGQCAAIEAARHGAKEVVIIEKETRLGGNSAKATSGINAWGTAVQKAAGVH 69

Query: 442 DGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTH 501
           D G+ FE+DT+ SG GG+  P LV+TLS  SA+AI WL+S G+PLT L+QLGG SRKR H
Sbjct: 70  DSGELFEKDTFASGKGGSCQPELVRTLSDHSAEAIEWLSSFGIPLTALTQLGGASRKRCH 129

Query: 502 RAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRV 561
           RAPD  DGTPLPIGFTI++ LE+++R NLS  + I  N  + SL+   ++       + V
Sbjct: 130 RAPDNPDGTPLPIGFTIVRALENYIRTNLSDIVRIETNARLISLMHSKED-----NAVVV 184

Query: 562 TGVEF-TQAGSGKTTI---LADAVILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWAT 617
            G+ + TQ  SG+  I    A AVILATGGFSND TA+SLL+++AP L +FPTTNG WAT
Sbjct: 185 QGITYATQTASGEGKIRKLQARAVILATGGFSNDHTANSLLQQYAPQLSSFPTTNGVWAT 244

Query: 618 GDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRF 677
           GDGVK A+ LG +LVDMDKVQLHPTGL++PKDP+N TK+LGPEALRGSGGVLLNK G+RF
Sbjct: 245 GDGVKAARELGVELVDMDKVQLHPTGLLDPKDPSNRTKYLGPEALRGSGGVLLNKNGERF 304

Query: 678 VNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKA 737
           VNELDLRSVVS+AI+EQ   YPGSGGS FAYCVLN AA KLFG +   FYW ++GLF K 
Sbjct: 305 VNELDLRSVVSQAIIEQNNVYPGSGGSKFAYCVLNEAAAKLFGKNFLGFYWHRLGLFEKV 364

Query: 738 DTMRDLAALIGCPVESVQQTLEEYERLSTSQ-RSCPITRKSVYPCVLGTKGPYYVAFVTP 796
           + +  LA LIGCP E+V  TL+EY+ LS+ +  +CP+T K+V+PC LGT+GPYYVAFVTP
Sbjct: 365 EDVAGLAKLIGCPEENVTATLKEYKELSSKKLHACPLTNKNVFPCTLGTEGPYYVAFVTP 424

Query: 797 SIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXXXXXXXXXXXXXNSLLE 856
           SIHYTMGGCLISPSAE+Q  + +   P+    PI GLF                 NSLLE
Sbjct: 425 SIHYTMGGCLISPSAEMQTIDNTGVTPVRR--PIPGLFGAGEVTGGVHGGNRLGGNSLLE 482

Query: 857 CVVFGRIAGDRASTILQRKSSAL 879
           CVVFGRIAG RA+ ILQ  ++ L
Sbjct: 483 CVVFGRIAGARAAAILQEGAAGL 505



>gi|72547421|ref|XP_843226.1| NADH-dependent fumarate reductase, putative [Leishmania major
           strain Friedlin]
 gi|70905705|gb|AAZ14344.1| NADH-dependent fumarate reductase, putative [Leishmania major
           strain Friedlin]
          Length = 495

 Score =  540 bits (1392), Expect = e-151,   Method: Composition-based stats.
 Identities = 289/492 (58%), Positives = 347/492 (70%), Gaps = 19/492 (3%)

Query: 383 RVIVVXXXXXXXXXXXXXXXCGA-QVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIV 441
           RV++V                GA +VVL+EKE +LGGNSAKATSGINGWGT  Q  A + 
Sbjct: 10  RVVIVGSGLAGQSAAIEAAREGAKEVVLIEKEGRLGGNSAKATSGINGWGTAVQKAAGVH 69

Query: 442 DGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTH 501
           D G+ FE+DT+ SG GG   P LV+TLS  SA+AI WL+S G+PLT ++QLGG SRKR H
Sbjct: 70  DSGELFEKDTFVSGKGGTCQPELVRTLSDHSAEAIEWLSSFGIPLTAITQLGGASRKRCH 129

Query: 502 RAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRV 561
           RAPDK DGTPLPIGFTI++ LE+++R NLSG + I  N  + SL+     R +   ++ V
Sbjct: 130 RAPDKPDGTPLPIGFTIVRALENYIRTNLSGTVLIESNARLISLI----HRKESDVEV-V 184

Query: 562 TGVEF-TQAGSGKTT---ILADAVILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWAT 617
            G+ + TQ GSG+     + A AVILATGGFSND T +SLL+++AP L +FPTTNG WAT
Sbjct: 185 QGITYATQTGSGEEQTRELQARAVILATGGFSNDHTPNSLLQQYAPQLSSFPTTNGVWAT 244

Query: 618 GDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRF 677
           GDGVK A+ LG  LVDMDKVQLHPTGL+NPKDP   T FLGPEALRGSGGVLLNK G+RF
Sbjct: 245 GDGVKAARELGVALVDMDKVQLHPTGLLNPKDPNAKTLFLGPEALRGSGGVLLNKNGERF 304

Query: 678 VNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKA 737
           VNELDLRSVVS+AI+ Q   YPG+    +AYCVLN AA   FG SS  FYWKKMGLF +A
Sbjct: 305 VNELDLRSVVSQAIIAQDNVYPGTESRRYAYCVLNDAAADAFGRSSLNFYWKKMGLFAEA 364

Query: 738 DTMRDLAALIGCPVESVQQTLEEYERLSTSQRSCPITRKSVYPCVLGTKGPYYVAFVTPS 797
             +  LAALIGCP E+++ TL EYE++S+ Q+ CP T K V+PCVLGT+GPYYVA VTPS
Sbjct: 365 ADVAALAALIGCPEETLKHTLSEYEKISSGQKPCPKTGKEVFPCVLGTQGPYYVALVTPS 424

Query: 798 IHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPILGLFXXXXXXXXXXXXXXXXXNSLLEC 857
           IHYTMGGCLISP+AEI  +           +PI GLF                 NSLLEC
Sbjct: 425 IHYTMGGCLISPAAEILDEQM---------HPIPGLFGAGEVTGGVHGGNRLGGNSLLEC 475

Query: 858 VVFGRIAGDRAS 869
           VVFGRIAG +A+
Sbjct: 476 VVFGRIAGRQAA 487



>gi|146100735|ref|XP_001468932.1| NADH-dependent fumarate reductase [Leishmania infantum]
 gi|134073301|emb|CAM72027.1| NADH-dependent fumarate reductase, putative [Leishmania infantum]
          Length = 495

 Score =  532 bits (1371), Expect = e-149,   Method: Composition-based stats.
 Identities = 283/468 (60%), Positives = 341/468 (72%), Gaps = 18/468 (3%)

Query: 406 QVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALV 465
           +VVL+EKEA+LGGNSAKATSGINGWGT  Q  A + D G+ FE+DT+ SG GG   P LV
Sbjct: 34  EVVLIEKEARLGGNSAKATSGINGWGTAVQKAAGVHDSGELFEKDTFVSGKGGTCRPELV 93

Query: 466 KTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDH 525
           +TLS  SA+AI WL+S G+PLT ++QLGG SRKR HRAPDK DGTPLPIG TI++ LE++
Sbjct: 94  RTLSDHSAEAIEWLSSFGIPLTAITQLGGASRKRCHRAPDKPDGTPLPIGSTIVRALENY 153

Query: 526 VRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRVTGVEF-TQAGSGKTT---ILADAV 581
           +R NLSG + I  N  + SL+  +KE   G  ++ V G+ + TQ GSG+     + A AV
Sbjct: 154 IRTNLSGTVLIETNARLISLI-HSKE---GGVEV-VQGITYATQTGSGEEQTRELQARAV 208

Query: 582 ILATGGFSNDKTADSLLREHAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHP 641
           ILATGGFSND T +SLL+++AP L +FPTTNG WATGDGVK A+ LG +LVDMDKVQLHP
Sbjct: 209 ILATGGFSNDHTPNSLLQQYAPQLSSFPTTNGVWATGDGVKAARELGVKLVDMDKVQLHP 268

Query: 642 TGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGS 701
           TGL+NPKDP   T FLGPEALRGSGGVLLNK G+RFVNEL LRSVVS+AI+ Q   YPG+
Sbjct: 269 TGLLNPKDPNAKTLFLGPEALRGSGGVLLNKNGERFVNELGLRSVVSQAIIAQNNVYPGT 328

Query: 702 GGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEY 761
               +AYCVLN AA   FG SS  FYWKKMGLF +   +  LAALIGCP E++  TL EY
Sbjct: 329 ESRRYAYCVLNDAAADAFGRSSLNFYWKKMGLFSEVADVAALAALIGCPEETLMHTLSEY 388

Query: 762 ERLSTSQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSR 821
           E++S+ ++ CP + K V+PCVLGT+GPYYVA VTPSIHYTMGGCLISP+AEI  +     
Sbjct: 389 EKISSGRKPCPKSGKEVFPCVLGTQGPYYVALVTPSIHYTMGGCLISPAAEILNEQM--- 445

Query: 822 APLSHSNPILGLFXXXXXXXXXXXXXXXXXNSLLECVVFGRIAGDRAS 869
                 +PILGLF                 NSLLECVVFGRIAG +A+
Sbjct: 446 ------HPILGLFGAGEVTGGVHGGNRLGGNSLLECVVFGRIAGRQAA 487



>gi|154344559|ref|XP_001568221.1| NADH-dependent fumarate reductase, putative [Leishmania
           braziliensis MHOM/BR/75/M2904]
 gi|134065558|emb|CAM43328.1| NADH-dependent fumarate reductase, putative [Leishmania
           braziliensis]
          Length = 543

 Score =  514 bits (1324), Expect = e-143,   Method: Composition-based stats.
 Identities = 275/468 (58%), Positives = 338/468 (72%), Gaps = 12/468 (2%)

Query: 417 GGNSAKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPALVKTLSMKSADAI 476
           G  +A++    N WGT  Q  A + D G+ FE+DT+ SG GG+  P LV+TLS  SA+AI
Sbjct: 74  GECAARSRENGNAWGTAVQKAAGVHDSGELFEKDTFASGKGGSCQPELVRTLSDHSAEAI 133

Query: 477 GWLTSLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLEDHVRGNLSGRITI 536
            WL+S G+PLT L+QLGG SRKR HRAPD  DGTPLPIGFTI++ LE+++R NLS  + I
Sbjct: 134 EWLSSFGIPLTALTQLGGASRKRCHRAPDNPDGTPLPIGFTIVRALENYIRTNLSDIVRI 193

Query: 537 MENCSVTSLLSETKERPDGTKQIRVTGVEF-TQAGSGKTTI---LADAVILATGGFSNDK 592
             N  + SL+   ++       + V G+ + TQ  SG+  I    A AVILATGGFSND 
Sbjct: 194 ETNARLISLMHSKED-----NAVVVQGITYATQTASGEGKIRKLQARAVILATGGFSNDH 248

Query: 593 TADSLLREHAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPTGLINPKDPAN 652
           TA+SLL+++AP L +FPTTNG WATGDGVK A+ LG +LVDMDKVQLHPTGL++PKDP+N
Sbjct: 249 TANSLLQQYAPQLSSFPTTNGVWATGDGVKAARELGVELVDMDKVQLHPTGLLDPKDPSN 308

Query: 653 PTKFLGPEALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSMFAYCVLN 712
            TK+LGPEALRGSGGVLLNK G+RFVNELDLRSVVS+AI+EQ   YPGSGGS FAYCVLN
Sbjct: 309 RTKYLGPEALRGSGGVLLNKNGERFVNELDLRSVVSQAIIEQNNVYPGSGGSKFAYCVLN 368

Query: 713 AAAQKLFGVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLSTSQ-RSC 771
            AA KLFG +   FYW ++GLF K + +  LA LIGCP E+V  TL+EY+ LS+ +  +C
Sbjct: 369 EAAAKLFGKNFLGFYWHRLGLFEKVEDVAGLAKLIGCPEENVTATLKEYKELSSKKLHAC 428

Query: 772 PITRKSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLSHSNPIL 831
           P+T K+V+PC LGT+GPYYVAFVTPSIHYTMGGCLISPSAE+Q  + +   P+    PI 
Sbjct: 429 PLTNKNVFPCTLGTEGPYYVAFVTPSIHYTMGGCLISPSAEMQTIDNTGVTPVRR--PIP 486

Query: 832 GLFXXXXXXXXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSAL 879
           GLF                 NSLLECVVFGRIAG RA+ ILQ  ++ L
Sbjct: 487 GLFGAGEVTGGVHGGNRLGGNSLLECVVFGRIAGARAAAILQEGAAGL 534



>gi|71419607|ref|XP_811221.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi strain
            CL Brener]
 gi|70875860|gb|EAN89370.1| NADH-dependent fumarate reductase, putative [Trypanosoma cruzi]
          Length = 470

 Score =  438 bits (1126), Expect = e-120,   Method: Composition-based stats.
 Identities = 237/488 (48%), Positives = 312/488 (63%), Gaps = 19/488 (3%)

Query: 646  NPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPGSGGSM 705
            +PKDPANPTK+LGPEALRGSGGVLLNK+G+RFVNELDLRSVVS AI+EQG EYP +GGS 
Sbjct: 1    DPKDPANPTKYLGPEALRGSGGVLLNKKGERFVNELDLRSVVSNAIIEQGDEYPDAGGSK 60

Query: 706  FAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEEYERLS 765
            FA+CVLN AA KLFGV+SH FYWK++GLFVKADT+  LAALIGCPVE+V+ TL +YE+LS
Sbjct: 61   FAFCVLNDAAVKLFGVNSHGFYWKRLGLFVKADTVEKLAALIGCPVENVRNTLGDYEQLS 120

Query: 766  TSQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKNTSSRAPLS 825
               R CP TRK VYPCV+G +GP+YVAFVTPSIHYTMGGCLISPSAE+Q++  ++ +P  
Sbjct: 121  KENRQCPKTRKVVYPCVVGPQGPFYVAFVTPSIHYTMGGCLISPSAEMQLEENTT-SPFG 179

Query: 826  HSNPILGLFXXXXXXXXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSSALSFKVWT 885
            H  PI GLF                 NSLLECVVFGRIAGDRA+TILQ   + L  + W+
Sbjct: 180  HRRPIFGLFGAGEVTGGVHGGNRLGGNSLLECVVFGRIAGDRAATILQNNDTYLWGEKWS 239

Query: 886  TVVLREVREGGVYGAGSRVLRFNLPGALQRSGLSLGQFIAIRGDWDGQQLIGYYSPITLP 945
             + LR V E      G   L F  P + Q SGL   Q + +R    G + +  Y+P TLP
Sbjct: 240  QLKLRNVMED---ENGFMWLHFTFPSSFQVSGLEALQGVVLR-SVSGDKSVEVYTPYTLP 295

Query: 946  DDLGMIDI-LARSDKGTLREWISALEPGDAVEMKACGGLVIERRLSDKHFVFMGHIINKL 1004
            DD G++ I L+    G    W+  L+PGD VEMKA      ER   +++++ M    +K+
Sbjct: 296  DDEGVVGIALSPWLTGNGVHWLRTLQPGDTVEMKAA-----ER--VERNYMNMLKAPHKV 348

Query: 1005 CLIAGGTGVAPMLQIIKAAFMKPFIDTLESVHLIYAAEDXXXXXXXXXXXXXXXXXXGKF 1064
             +IA   G+APM+QI++A   +P  D   ++HLIY A+                    +F
Sbjct: 349  -VIATSRGIAPMMQILRATMERPEKDA--TIHLIYIADRASSIPYREKLKALAEASPERF 405

Query: 1065 KKTFVLNRPPPLWTDGVGFIDRGILTNHVQPPSDNLLVAICGPPVMQRIVKATLKTLGYN 1124
            + TFVL  P P W+  V ++D    +     P   +++ +CG     R +K++L  +G++
Sbjct: 406  RCTFVLQHPQPGWSGAVNYLDEIAASVF---PDPAVVIFLCGASEETRSIKSSLLDMGHD 462

Query: 1125 MNLVRTVD 1132
            +  + TV+
Sbjct: 463  VATIATVE 470



>gi|71986328|ref|NP_498164.3| F48E8.3 [Caenorhabditis elegans]
 gi|46195886|gb|AAC46539.3| Hypothetical protein F48E8.3 [Caenorhabditis elegans]
          Length = 493

 Score =  312 bits (799), Expect = 1e-82,   Method: Composition-based stats.
 Identities = 189/472 (40%), Positives = 261/472 (55%), Gaps = 25/472 (5%)

Query: 404 GAQVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPA 463
           G +V+L+E E   GGNSAKA+SGING GT  Q K  I D  +   +DT  +G   N D  
Sbjct: 31  GGRVILVEGEGNTGGNSAKASSGINGAGTETQEKLGIKDSPELLVKDTLSAGDSEN-DKK 89

Query: 464 LVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLE 523
           LV+ L+  SADA+ +L  + V LT ++  GGHS  RTH  P  K+G P+P GF IMK L 
Sbjct: 90  LVEILAANSADAVEFLRGVEVDLTDVNLCGGHSVPRTHWIPSPKEGRPIPAGFEIMKRLR 149

Query: 524 DHVRGNLSGRITIMENCSVTSLLSETKERPDGTKQIRVTGVEFTQAGSG-KTTILADAVI 582
             +    S      EN     LL++TK      +  +V+G+E   + SG K+ I+ DAVI
Sbjct: 150 TRLNEKQS------ENPEAFKLLTQTKMVGILRENGKVSGIEIVTSASGEKSKIIGDAVI 203

Query: 583 LATGGFSNDKTADSLLREHAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLHPT 642
           LATGGFS D+T   LL+E    +  FPTTNG +A GDGVK+A+ LGA+++ M+ +Q+HPT
Sbjct: 204 LATGGFSADET---LLKEFGAEIFGFPTTNGAFAKGDGVKIARALGAKIIGMENIQIHPT 260

Query: 643 GLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELDLRSVVSKAIME-----QGAE 697
             ++PKDP+  TKFL  EA+RG G +L+N +G+RF NEL  R  ++  I+E     + + 
Sbjct: 261 AFVDPKDPSAGTKFLAAEAIRGKGALLINSKGQRFGNELGRRDYLTGKILELAEPIEESF 320

Query: 698 YPGSGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQT 757
             GS G   A  ++N A  + FG  +  FY      F K +   +LA  +G    +++ T
Sbjct: 321 QGGSAGRNAAIMIMNEANVEAFGRPAFNFYSIVKKFFAKYENSAELAKALGIDESAIKTT 380

Query: 758 LEEYERLSTSQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKN 817
           LEEY++    +   P  +K      +    P Y A V P+IHYTMGG  I         +
Sbjct: 381 LEEYQKSFDGKSEDPFGKKVFPVSAISPTEPIYAAIVVPAIHYTMGGLKI---------D 431

Query: 818 TSSRAPLSHSNPILGLFXXXXXXXXXXXXXXXXXNSLLECVVFGRIAGDRAS 869
            ++R    H  PI+GLF                 NSLLECVVFGRIAG  A+
Sbjct: 432 EATRVIDEHGKPIVGLFAAGEVTGGVHGSNRLAGNSLLECVVFGRIAGKSAA 483



>gi|170573380|ref|XP_001892448.1| Hypothetical FAD-dependent oxidoreductase YEL047C, putative [Brugia
           malayi]
 gi|158602014|gb|EDP38735.1| Hypothetical FAD-dependent oxidoreductase YEL047C, putative [Brugia
           malayi]
          Length = 544

 Score =  299 bits (766), Expect = 8e-79,   Method: Composition-based stats.
 Identities = 198/481 (41%), Positives = 261/481 (54%), Gaps = 20/481 (4%)

Query: 404 GAQVVLMEKEAKLGGNSAKATSGINGWGTRAQAKASIVDGGKYFERDTYKSGIGGNTDPA 463
           GA VVL+E E  LGGNS KA+SGI    T AQ    I D  + F  DT  +G   N D  
Sbjct: 71  GANVVLVEGEKDLGGNSQKASSGIAACNTEAQRVRQIHDSSELFYSDTMSAGDREN-DHI 129

Query: 464 LVKTLSMKSADAIGWLTSLGVPLTVLSQLGGHSRKRTHRAPDKKDGTPLPIGFTIMKTLE 523
           LV  L   S  A+ +L   GV L+ ++  GGHS KR H  P  K+G P+ +G +I+K L+
Sbjct: 130 LVDQLVRHSPTAVQFLIDHGVNLSDINLCGGHSVKRVHWIPQPKEGKPVAVGVSIIKALK 189

Query: 524 DHVRGNLSGRITIMENCSVTS--LLSETKERPDGTKQIRVTGVEFTQAGSGKTTILADAV 581
           + +R +         N  + S  +L  T+     T    VTGV   + GS    I   AV
Sbjct: 190 EKLRMHEKDNPEKCWNLKIFSVRILLGTEVVGLVTWNDFVTGVRI-KNGSQIDEISGKAV 248

Query: 582 ILATGGFSNDKTA-DSLLREHAPHLVNFPTTNGPWATGDGVKLAQRLGAQLVDMDKVQLH 640
           +L TGGFS D +  DSLL+E AP   +FPTTNGPWATG GVK+A+ +GA LV M  VQ+H
Sbjct: 249 VLTTGGFSCDHSKEDSLLQEFAPEKADFPTTNGPWATGRGVKMARAMGAALVGMHNVQIH 308

Query: 641 PTGLINPKDPANPTKFLGPEALRGSGGVLLNKQGKRFVNELDLRSVVSKAIMEQGAEYPG 700
           PT  ++PKDPA  TKFL  EALRG G +LLN +G+RFVNEL  R  V+  I++  A+   
Sbjct: 309 PTAFVDPKDPAAATKFLAAEALRGKGAILLNDKGERFVNELGRRDHVTDKILKFCAKNEK 368

Query: 701 SGGSMFAYCVLNAAAQKLFGVSSHEFYWKKMGLFVKADTMRDLAALIGCPVESVQQTLEE 760
           +G    A+ V++  A + FG +S  FY K  G F + DT+ + A  +G     +++TL+E
Sbjct: 369 AGAHT-AFMVMDDQAVEDFGRASFGFYAKIKGFFKQFDTLEEAANYMGIQSSKLKETLDE 427

Query: 761 YE---RLSTSQRSCPITRKSVYPCVLGTKGPYYVAFVTPSIHYTMGGCLISPSAEIQMKN 817
           Y    +LS S+       K V+P  L    PYYVA +TP+IHYTMGG  I   A +  + 
Sbjct: 428 YNEYTKLSLSKED--KFGKKVFPVAL-KHPPYYVAVITPAIHYTMGGIKIDKDAAVYNEF 484

Query: 818 TSSRAPLSHSNPILGLFXXXXXXXXXXXXXXXXXNSLLECVVFGRIAGDRASTILQRKSS 877
           +          P  GL                  NSLLECVV+GRIAG  A+ I    S 
Sbjct: 485 S--------GKPFKGLLAAGEVTGGVHGRNRLAGNSLLECVVYGRIAGRNAANIRYSASD 536

Query: 878 A 878
           A
Sbjct: 537 A 537