BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= AAX79089.1__[Trypanosoma_brucei]
(491 letters)
Database: nr.pal
6,348,806 sequences; 2,166,943,470 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|72389174|ref|XP_844882.1| inosine-5'-monophosphate dehyd... 840 0.0
gi|71425432|ref|XP_813108.1| inosine-5'-monophosphate dehyd... 632 e-179
gi|71667098|ref|XP_820501.1| inosine-5'-monophosphate dehyd... 632 e-179
gi|157867562|ref|XP_001682335.1| inosine-5'-monophosphate d... 627 e-178
gi|146083468|ref|XP_001464746.1| inosine-5'-monophosphate d... 621 e-176
gi|154335212|ref|XP_001563846.1| inosine-5'-monophosphate d... 616 e-174
gi|154248815|ref|YP_001409640.1| inosine-5'-monophosphate d... 365 5e-99
gi|118195694|gb|ABK78612.1| IMP dehydrogenase/GMP reductase... 363 1e-98
gi|154507797|ref|ZP_02043439.1| hypothetical protein ACTODO... 363 2e-98
gi|78042653|ref|YP_360021.1| inosine-5'-monophosphate dehyd... 362 3e-98
gi|161529077|ref|YP_001582903.1| inosine-5'-monophosphate d... 362 4e-98
gi|114566449|ref|YP_753603.1| IMP dehydrogenase [Syntrophom... 361 7e-98
gi|121535780|ref|ZP_01667581.1| inosine-5'-monophosphate de... 360 1e-97
gi|50843228|ref|YP_056455.1| IMP dehydrogenase / GMP reduct... 360 2e-97
gi|15607007|ref|NP_214389.1| inosine monophosphate dehydrog... 360 2e-97
gi|146296720|ref|YP_001180491.1| inosine-5'-monophosphate d... 358 5e-97
gi|163782022|ref|ZP_02177021.1| inosine monophosphate dehyd... 356 2e-96
gi|150021453|ref|YP_001306807.1| inosine-5'-monophosphate d... 353 1e-95
gi|119717867|ref|YP_924832.1| inosine-5'-monophosphate dehy... 353 2e-95
gi|138893688|ref|YP_001124141.1| inositol-5-monophosphate d... 352 5e-95
gi|56418544|ref|YP_145862.1| inositol-5-monophosphate dehyd... 351 7e-95
gi|89211833|ref|ZP_01190168.1| IMP dehydrogenase [Halotherm... 351 9e-95
gi|152973862|ref|YP_001373379.1| inosine-5'-monophosphate d... 350 2e-94
gi|6705995|dbj|BAA89464.1| IMPDH [Bacillus cereus] 349 2e-94
gi|6561887|dbj|BAA88235.1| IMP dehydrogenase [Bacillus cereus] 349 3e-94
gi|152964711|ref|YP_001360495.1| inosine-5'-monophosphate d... 348 4e-94
gi|30018286|ref|NP_829917.1| inositol-5-monophosphate dehyd... 348 5e-94
gi|75764313|ref|ZP_00743847.1| Inosine-5'-monophosphate deh... 348 6e-94
gi|42779090|ref|NP_976337.1| inositol-5-monophosphate dehyd... 347 1e-93
gi|163938021|ref|YP_001642905.1| inosine-5'-monophosphate d... 346 2e-93
gi|49476689|ref|YP_034368.1| inositol-5-monophosphate dehyd... 346 2e-93
gi|167630470|ref|YP_001680969.1| inosine-5'-monophosphate d... 346 3e-93
gi|30260202|ref|NP_842579.1| inositol-5-monophosphate dehyd... 345 3e-93
gi|126652925|ref|ZP_01725067.1| inositol-5-monophosphate de... 345 3e-93
gi|169825631|ref|YP_001695789.1| Inosine-5'-monophosphate d... 345 3e-93
gi|67940681|ref|ZP_00533047.1| IMP dehydrogenase [Chlorobiu... 345 4e-93
gi|169831232|ref|YP_001717214.1| inosine-5'-monophosphate d... 345 4e-93
gi|160946360|ref|ZP_02093569.1| hypothetical protein PEPMIC... 345 6e-93
gi|65317475|ref|ZP_00390434.1| COG0516: IMP dehydrogenase/G... 345 6e-93
gi|84497912|ref|ZP_00996709.1| inosine-5'-monophosphate deh... 344 7e-93
gi|27262442|gb|AAN87502.1| Inosine-5'-monophosphate dehydro... 344 7e-93
gi|119963910|ref|YP_948576.1| inosine-5'-monophosphate dehy... 344 8e-93
gi|170289271|ref|YP_001739509.1| inosine-5'-monophosphate d... 344 8e-93
gi|15644099|ref|NP_229148.1| inosine-5'-monophosphate dehyd... 344 1e-92
gi|62738150|pdb|1VRD|A Chain A, Crystal Structure Of Inosin... 344 1e-92
gi|147677653|ref|YP_001211868.1| hypothetical protein PTH_1... 343 1e-92
gi|163791205|ref|ZP_02185622.1| inositol-5-monophosphate de... 343 1e-92
gi|116749553|ref|YP_846240.1| inosine-5'-monophosphate dehy... 343 1e-92
gi|68056187|ref|ZP_00540318.1| IMP dehydrogenase [Exiguobac... 343 1e-92
gi|166997063|ref|ZP_02263522.1| inositol-5-monophosphate de... 343 2e-92
gi|86739349|ref|YP_479749.1| inosine-5'-monophosphate dehyd... 343 2e-92
gi|15612583|ref|NP_240886.1| inositol-5-monophosphate dehyd... 343 2e-92
gi|156719076|ref|ZP_02060725.1| inosine-5'-monophosphate de... 343 2e-92
gi|20807078|ref|NP_622249.1| IMP dehydrogenase/GMP reductas... 342 4e-92
gi|56961793|ref|YP_173515.1| inositol-5-monophosphate dehyd... 342 5e-92
gi|170780972|ref|YP_001709304.1| inosine-5'-monophosphate d... 342 5e-92
gi|163840509|ref|YP_001624914.1| inosine-5'-monophosphate d... 341 9e-92
gi|78223496|ref|YP_385243.1| IMP dehydrogenase [Geobacter m... 340 1e-91
gi|169190539|ref|ZP_02850469.1| inosine-5'-monophosphate de... 340 1e-91
gi|167038115|ref|YP_001665693.1| response regulator receive... 339 2e-91
gi|116671425|ref|YP_832358.1| inosine-5'-monophosphate dehy... 339 2e-91
gi|51894052|ref|YP_076743.1| inosine-5'-monophosphate dehyd... 339 3e-91
gi|29831543|ref|NP_826177.1| inosine-5'-monophosphate dehyd... 339 4e-91
gi|72162995|ref|YP_290652.1| IMP dehydrogenase [Thermobifid... 338 5e-91
gi|88855849|ref|ZP_01130512.1| inosine-5'-monophosphate deh... 338 5e-91
gi|118580427|ref|YP_901677.1| inosine-5'-monophosphate dehy... 338 5e-91
gi|89100965|ref|ZP_01173811.1| inositol-5-monophosphate deh... 338 6e-91
gi|111220602|ref|YP_711396.1| IMP dehydrogeanse [Frankia al... 338 8e-91
gi|154684527|ref|YP_001419688.1| GuaB [Bacillus amyloliquef... 337 1e-90
gi|119025468|ref|YP_909313.1| Inosine-5'-monophosphate dehy... 336 2e-90
gi|118746138|ref|ZP_01594091.1| inosine-5'-monophosphate de... 336 2e-90
gi|39959|emb|CAA39204.1| IMP dehydrogenase [Bacillus subtilis] 336 2e-90
gi|148273745|ref|YP_001223306.1| inosine-5'-monophosphate d... 336 2e-90
gi|16077077|ref|NP_387890.1| inositol-5-monophosphate dehyd... 336 2e-90
gi|154486895|ref|ZP_02028302.1| hypothetical protein BIFADO... 336 2e-90
gi|46198372|ref|YP_004039.1| inosine-5'-monophosphate dehyd... 336 3e-90
gi|55980401|ref|YP_143698.1| 'IMP dehydrogenase/GMP reducta... 336 3e-90
gi|39997293|ref|NP_953244.1| inosine-5'-monophosphate dehyd... 335 5e-90
gi|145618584|ref|ZP_01774642.1| inosine-5'-monophosphate de... 335 5e-90
gi|21223149|ref|NP_628928.1| inosine 5' monophosphate dehyd... 335 6e-90
gi|134103138|ref|YP_001108799.1| inosine-5'-monophosphate d... 333 1e-89
gi|157691297|ref|YP_001485759.1| IMP dehydrogenase [Bacillu... 333 2e-89
gi|154501514|ref|ZP_02039215.1| hypothetical protein BACCAP... 333 2e-89
gi|148265152|ref|YP_001231858.1| inosine-5'-monophosphate d... 333 2e-89
gi|69247502|ref|ZP_00604372.1| IMP dehydrogenase [Enterococ... 333 2e-89
gi|152991023|ref|YP_001356745.1| inosine-5'-monophosphate d... 333 2e-89
gi|120436847|ref|YP_862533.1| IMP dehydrogenase [Gramella f... 332 3e-89
gi|134299756|ref|YP_001113252.1| inosine-5'-monophosphate d... 332 3e-89
gi|153809073|ref|ZP_01961741.1| hypothetical protein BACCAC... 332 4e-89
gi|160882389|ref|ZP_02063392.1| hypothetical protein BACOVA... 332 5e-89
gi|83589956|ref|YP_429965.1| inosine-5'-monophosphate dehyd... 332 5e-89
gi|52078500|ref|YP_077291.1| inosine-monophosphate dehydrog... 332 5e-89
gi|110600018|ref|ZP_01388248.1| inosine-5'-monophosphate de... 331 6e-89
gi|73663632|ref|YP_302413.1| IMP dehydrogenase [Staphylococ... 331 7e-89
gi|150388740|ref|YP_001318789.1| inosine-5'-monophosphate d... 331 8e-89
gi|114777703|ref|ZP_01452663.1| inosine-5'-monophosphate de... 331 8e-89
gi|15923380|ref|NP_370914.1| inositol-monophosphate dehydro... 331 9e-89
gi|18976657|ref|NP_578014.1| inositol-5-monophosphate dehyd... 331 9e-89
gi|62424696|ref|ZP_00379838.1| COG0516: IMP dehydrogenase/G... 330 1e-88
gi|38233189|ref|NP_938956.1| inositol-5-monophosphate dehyd... 330 1e-88
>gi|72389174|ref|XP_844882.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma
brucei TREU927]
gi|62358631|gb|AAX79089.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma
brucei]
gi|70801416|gb|AAZ11323.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma
brucei]
Length = 491
Score = 840 bits (2169), Expect = 0.0, Method: Composition-based stats.
Identities = 456/491 (92%), Positives = 456/491 (92%)
Query: 1 MSFNESASIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQ 60
MSFNESASIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQ
Sbjct: 1 MSFNESASIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQ 60
Query: 61 RMAVAMAREGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNW 120
RMAVAMAREGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNW
Sbjct: 61 RMAVAMAREGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNW 120
Query: 121 KXXXXXXXXXXXXNCKNERKLLGIITRHDLKLADESTTVESLMTPVDKMVVSTNTSISLE 180
K NCKNERKLLGIITRHDLKLADESTTVESLMTPVDKMVVSTNTSISLE
Sbjct: 121 KGRVGGVGCLLVVNCKNERKLLGIITRHDLKLADESTTVESLMTPVDKMVVSTNTSISLE 180
Query: 181 EVTHLMRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKD 240
EVTHLMRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKD
Sbjct: 181 EVTHLMRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKD 240
Query: 241 DMNRAIRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXX 300
DMNRAIRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVD
Sbjct: 241 DMNRAIRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDIIAGNIASAEAAEAL 300
Query: 301 XXXXXXXXKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDI 360
KIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDI
Sbjct: 301 IDAGADGLKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDI 360
Query: 361 SKAIGAGADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDED 420
SKAIGAGADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDED
Sbjct: 361 SKAIGAGADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDED 420
Query: 421 VFSSLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGL 480
VFSSLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGL
Sbjct: 421 VFSSLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGL 480
Query: 481 RESGSHGVAKL 491
RESGSHGVAKL
Sbjct: 481 RESGSHGVAKL 491
>gi|71425432|ref|XP_813108.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma cruzi
strain CL Brener]
gi|70877961|gb|EAN91257.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma
cruzi]
Length = 491
Score = 632 bits (1631), Expect = e-179, Method: Composition-based stats.
Identities = 329/491 (67%), Positives = 392/491 (79%)
Query: 1 MSFNESASIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQ 60
MS + SIP LTYDDVL++PQ S V SRK+V+TTTRLSRN+KL IPIVASNMDTVCE
Sbjct: 1 MSVSGVGSIPVALTYDDVLLVPQKSPVRSRKDVSTTTRLSRNIKLHIPIVASNMDTVCEH 60
Query: 61 RMAVAMAREGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNW 120
+ A+AMAREGGIGILHRFCSI EQC ML +VKRAQSFLIE+PR+I+ H+T EA +GL W
Sbjct: 61 QTAIAMAREGGIGILHRFCSIREQCEMLSKVKRAQSFLIENPRMIMAHQTQEEALQGLQW 120
Query: 121 KXXXXXXXXXXXXNCKNERKLLGIITRHDLKLADESTTVESLMTPVDKMVVSTNTSISLE 180
K + RKLLGI++++DL AD + V LMTP++++VVSTNT+I+LE
Sbjct: 121 KGRKGGVSCLMVVEDFSTRKLLGIVSKNDLHFADANEPVSKLMTPLERLVVSTNTAITLE 180
Query: 181 EVTHLMRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKD 240
E +MR+ RT N+PI+G++ L+YLVTLSDV+KL K ASLD+RGRLLVGAAVGVKK+
Sbjct: 181 EAREMMREHRTFNIPILGKDNALIYLVTLSDVLKLTGKKYASLDARGRLLVGAAVGVKKE 240
Query: 241 DMNRAIRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXX 300
D+ RA +LVEAGADVLVVDIAHGHS +CI+M+K+LK DPRT VD
Sbjct: 241 DITRAAKLVEAGADVLVVDIAHGHSSICIDMIKKLKTDPRTNKVDIVAGNIATGEAAAEL 300
Query: 301 XXXXXXXXKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDI 360
KIGVGPGSIC TRLVAG+GVPQLSAV+ CTRVAR+ GVPCIADGG++ +GDI
Sbjct: 301 ILAGADGLKIGVGPGSICTTRLVAGSGVPQLSAVMECTRVARKHGVPCIADGGIKMAGDI 360
Query: 361 SKAIGAGADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDED 420
KAI AGADTVM+GN+LAGT+EAPGRVLVKDG+KVK+IRGMAGFGANLSKAERE++ DED
Sbjct: 361 CKAIAAGADTVMVGNILAGTEEAPGRVLVKDGKKVKVIRGMAGFGANLSKAEREQSLDED 420
Query: 421 VFSSLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGL 480
VF+ +VPEGVEGSV CKGP+ PIVRQLVGGLRSGMSY GA I+EMQ+ RFVRMTG+GL
Sbjct: 421 VFAEMVPEGVEGSVPCKGPLAPIVRQLVGGLRSGMSYCGATCIKEMQQNARFVRMTGSGL 480
Query: 481 RESGSHGVAKL 491
RESGSH ++KL
Sbjct: 481 RESGSHSISKL 491
>gi|71667098|ref|XP_820501.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma cruzi
strain CL Brener]
gi|70885849|gb|EAN98650.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma
cruzi]
Length = 491
Score = 632 bits (1630), Expect = e-179, Method: Composition-based stats.
Identities = 328/491 (66%), Positives = 392/491 (79%)
Query: 1 MSFNESASIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQ 60
MS + SIP LTYDDVL++PQ S V SRK+V+TTTRLSRN+KL IPIVASNMDTVCE
Sbjct: 1 MSVSGVGSIPVALTYDDVLLVPQKSPVRSRKDVSTTTRLSRNIKLHIPIVASNMDTVCEH 60
Query: 61 RMAVAMAREGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNW 120
+ A+AMAREGGIGILHRFCSI EQC ML +VKRAQSFLIE+PR+I+ H+T EA +GL W
Sbjct: 61 QTAIAMAREGGIGILHRFCSIREQCEMLSKVKRAQSFLIENPRMIMAHQTQEEALQGLQW 120
Query: 121 KXXXXXXXXXXXXNCKNERKLLGIITRHDLKLADESTTVESLMTPVDKMVVSTNTSISLE 180
K + RKLLGI++++DL AD + V LMTP++++VVSTNT+I+LE
Sbjct: 121 KGRKGGVSCLMVVENFSTRKLLGIVSKNDLHFADANEPVSKLMTPLERLVVSTNTAITLE 180
Query: 181 EVTHLMRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKD 240
E +MR+ RT+N+PI+G++ L+YLVTLSDV+KL K ASLD+RGRLLVGAAVGVKK+
Sbjct: 181 EAREMMREHRTSNIPILGKDNALIYLVTLSDVLKLTGKKHASLDARGRLLVGAAVGVKKE 240
Query: 241 DMNRAIRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXX 300
D+ RA +LVEAGADVLVVDIAHGHS +CI+M+K+LK DPRT VD
Sbjct: 241 DITRAAKLVEAGADVLVVDIAHGHSSICIDMIKKLKTDPRTNKVDIVAGNIATGEAAAEL 300
Query: 301 XXXXXXXXKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDI 360
KIGVGPGSIC TRLVAG+GVPQLSAV+ CTRVAR+ GVPCIADGG++ +GDI
Sbjct: 301 ILAGADGLKIGVGPGSICTTRLVAGSGVPQLSAVMECTRVARKHGVPCIADGGIKMAGDI 360
Query: 361 SKAIGAGADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDED 420
KAI AGAD+VM+GN+LAGT+EAPGRVLVKDG+KVK+IRGMAGFGANLSKAERE++ DED
Sbjct: 361 CKAIAAGADSVMVGNILAGTEEAPGRVLVKDGKKVKVIRGMAGFGANLSKAEREQSLDED 420
Query: 421 VFSSLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGL 480
VF+ +VPEGVEGSV CKGP+ PIVRQLVGGLRSGMSY GA I EMQ+ RFVRMTG+GL
Sbjct: 421 VFAEMVPEGVEGSVPCKGPLAPIVRQLVGGLRSGMSYCGATCINEMQQNARFVRMTGSGL 480
Query: 481 RESGSHGVAKL 491
RESGSH ++KL
Sbjct: 481 RESGSHSISKL 491
>gi|157867562|ref|XP_001682335.1| inosine-5'-monophosphate dehydrogenase [Leishmania major]
gi|68125788|emb|CAJ03667.1| inosine-5'-monophosphate dehydrogenase [Leishmania major]
Length = 553
Score = 627 bits (1616), Expect = e-178, Method: Composition-based stats.
Identities = 326/484 (67%), Positives = 380/484 (78%)
Query: 8 SIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMA 67
++P GLTYDDVL+IPQ S V SRK VNT+TRLSRN+ L IPIVASNMDTVCE + AV MA
Sbjct: 70 TLPEGLTYDDVLLIPQRSPVRSRKAVNTSTRLSRNIHLKIPIVASNMDTVCEDKTAVTMA 129
Query: 68 REGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXX 127
REGGIGILHRFCSIEEQCAM+R+VKRAQSFLIE PR+ILP T EA E LNW
Sbjct: 130 REGGIGILHRFCSIEEQCAMVRKVKRAQSFLIEDPRMILPSATKAEALEELNWSGRKGGV 189
Query: 128 XXXXXXNCKNERKLLGIITRHDLKLADESTTVESLMTPVDKMVVSTNTSISLEEVTHLMR 187
+ R+L G++T+ DL A S VE+LMTPV +MVVSTNT+I+LEE +MR
Sbjct: 190 SCLMVVDDLTSRRLCGVLTKSDLTFATGSALVETLMTPVSRMVVSTNTAITLEEAREVMR 249
Query: 188 KGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIR 247
RT N+P++G G+LLYL+T SD++KL N A+LDSRGRL+VGAA+GVKK+D RA
Sbjct: 250 TKRTKNIPLLGPKGELLYLITRSDILKLTGNLNATLDSRGRLIVGAAIGVKKEDHERAAA 309
Query: 248 LVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXX 307
LV+AGADVLVVDIAHGHSDLCI+MVK LK +P T VD
Sbjct: 310 LVDAGADVLVVDIAHGHSDLCIDMVKALKVNPLTNKVDIIAGNIATAEAAQDLIDAGADG 369
Query: 308 XKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAG 367
KIGVGPGSICITRLVAG+GVPQLS+V+ C RVA++ GVPCIADGG++T+GDI KAI AG
Sbjct: 370 LKIGVGPGSICITRLVAGSGVPQLSSVMDCARVAKKHGVPCIADGGIKTAGDICKAIAAG 429
Query: 368 ADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFSSLVP 427
ADTVMLGNMLAGTDEAPGRVLVKDG+KVKIIRGMAGFGAN+SKAERE+ DEDVF LVP
Sbjct: 430 ADTVMLGNMLAGTDEAPGRVLVKDGKKVKIIRGMAGFGANISKAEREQRLDEDVFHDLVP 489
Query: 428 EGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHG 487
EGVEGSV CKGP+ PI++QLVGGLRSG+SY G+ SI +MQ+R RFVRM+GAGLRESGSH
Sbjct: 490 EGVEGSVPCKGPLAPILKQLVGGLRSGISYCGSHSIADMQQRARFVRMSGAGLRESGSHD 549
Query: 488 VAKL 491
++KL
Sbjct: 550 ISKL 553
>gi|146083468|ref|XP_001464746.1| inosine-5'-monophosphate dehydrogenase [Leishmania infantum JPCM5]
gi|134068840|emb|CAM59774.1| inosine-5'-monophosphate dehydrogenase [Leishmania infantum]
Length = 492
Score = 621 bits (1601), Expect = e-176, Method: Composition-based stats.
Identities = 325/484 (67%), Positives = 383/484 (79%)
Query: 8 SIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMA 67
++P GLTYDDVL+IPQ S V SRK VNT+TRLSRN+ L IPIVASNMDTVCE + AV MA
Sbjct: 9 TLPEGLTYDDVLLIPQRSPVRSRKAVNTSTRLSRNIHLKIPIVASNMDTVCEDKTAVTMA 68
Query: 68 REGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXX 127
REGGIGILHRFCSIEEQCAM+R+VKRAQSFLIE PR+ILP T EA E LNW
Sbjct: 69 REGGIGILHRFCSIEEQCAMVRKVKRAQSFLIEDPRMILPSATKAEALEELNWSGRKGGV 128
Query: 128 XXXXXXNCKNERKLLGIITRHDLKLADESTTVESLMTPVDKMVVSTNTSISLEEVTHLMR 187
+ R+L G++++ DL A +S VE+LMTPV + VVSTNT+I+LEE +MR
Sbjct: 129 SCLMVVDDFTSRRLCGVLSKSDLIFATDSALVETLMTPVSRTVVSTNTAITLEEAREVMR 188
Query: 188 KGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIR 247
RT+N+P++G G+LLYL+T SD++KL N+ A+LDSRGRL+VGAA+GVKK+D RA
Sbjct: 189 TKRTSNIPLLGPKGELLYLITQSDILKLTGNRNATLDSRGRLIVGAAIGVKKEDHKRAAA 248
Query: 248 LVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXX 307
LV+AGADVLVVDIAHGHSDLCI+MVK LK +P T VD
Sbjct: 249 LVDAGADVLVVDIAHGHSDLCIDMVKALKVNPLTNKVDIIAGNIATAEAAQDLIDAGADG 308
Query: 308 XKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAG 367
KIGVGPGSICITRLVAG+GVPQLSAV+ C RVA++ GVPCIADGG++T+GDI KAI AG
Sbjct: 309 LKIGVGPGSICITRLVAGSGVPQLSAVMDCARVAKKHGVPCIADGGVKTAGDICKAIAAG 368
Query: 368 ADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFSSLVP 427
ADTVMLGNMLAGTDEAPGRVLVKDG+KVKIIRGMAGFGAN+SKAERE+ DEDVF+ LVP
Sbjct: 369 ADTVMLGNMLAGTDEAPGRVLVKDGKKVKIIRGMAGFGANISKAEREKRLDEDVFNDLVP 428
Query: 428 EGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHG 487
EGVEGSV CKGP+ PI++QLVGGLRSG+SY G+ SI +MQ+R RFVRM+GAGLRESGSH
Sbjct: 429 EGVEGSVPCKGPLAPILKQLVGGLRSGISYCGSHSIADMQQRARFVRMSGAGLRESGSHD 488
Query: 488 VAKL 491
++KL
Sbjct: 489 ISKL 492
>gi|154335212|ref|XP_001563846.1| inosine-5'-monophosphate dehydrogenase [Leishmania braziliensis
MHOM/BR/75/M2904]
gi|134060875|emb|CAM37892.1| inosine-5'-monophosphate dehydrogenase [Leishmania braziliensis]
Length = 492
Score = 616 bits (1588), Expect = e-174, Method: Composition-based stats.
Identities = 321/484 (66%), Positives = 377/484 (77%)
Query: 8 SIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMA 67
++P GLTYDDVL+IPQ S V SRK VNT+T LSRN++L IPIVASNMDTVCE + AV MA
Sbjct: 9 TLPQGLTYDDVLLIPQRSPVRSRKAVNTSTHLSRNIRLKIPIVASNMDTVCEDKTAVTMA 68
Query: 68 REGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXX 127
REGGIGILHRFCSIEEQCAM+R+VKRAQSFLIE PR+IL T EA E LNW
Sbjct: 69 REGGIGILHRFCSIEEQCAMVRKVKRAQSFLIEDPRMILSSATKTEALEELNWSGRKGGV 128
Query: 128 XXXXXXNCKNERKLLGIITRHDLKLADESTTVESLMTPVDKMVVSTNTSISLEEVTHLMR 187
+ R+L G++++ DL A +S + +LMTPV +MVVSTNTSI+LEE LM
Sbjct: 129 SCLMVVDDFTSRRLCGVLSKSDLVFASDSDLIGTLMTPVKRMVVSTNTSITLEEARELMH 188
Query: 188 KGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIR 247
RT N+P++G G+LLYL+T SD++KL N+ A+LDSRGRL+VGAA+GVK +D RA
Sbjct: 189 MKRTNNIPLLGPKGELLYLITQSDILKLTGNRNATLDSRGRLIVGAAIGVKNEDHKRAAA 248
Query: 248 LVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXX 307
LV+AG DVLVVDIAHGHSDLCI+MVK LK +PRT VD
Sbjct: 249 LVDAGVDVLVVDIAHGHSDLCIDMVKALKANPRTNKVDIIAGNIATAEAAQDLIDAGADG 308
Query: 308 XKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAG 367
K+GVGPGSICITRLVAGAGVPQLSAV+ C RVA++ GVPCIADGG++T+GDI KAI AG
Sbjct: 309 LKVGVGPGSICITRLVAGAGVPQLSAVMDCARVAKKHGVPCIADGGVKTAGDICKAIAAG 368
Query: 368 ADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFSSLVP 427
ADTVMLGNMLAGTDEAPGR LVKDG+KVKIIRGMAGFGAN+SKAERE+ DEDVF+ LVP
Sbjct: 369 ADTVMLGNMLAGTDEAPGRALVKDGKKVKIIRGMAGFGANISKAEREKRLDEDVFNDLVP 428
Query: 428 EGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHG 487
EGVEGSV CKGP+ PI++QLVGGLRSG+SY GA SI EMQ+ +FVRM+GAGLRESGSH
Sbjct: 429 EGVEGSVPCKGPLAPILQQLVGGLRSGISYCGAHSIAEMQQHAKFVRMSGAGLRESGSHD 488
Query: 488 VAKL 491
++KL
Sbjct: 489 ISKL 492
>gi|154248815|ref|YP_001409640.1| inosine-5'-monophosphate dehydrogenase [Fervidobacterium nodosum
Rt17-B1]
gi|154152751|gb|ABS59983.1| inosine-5'-monophosphate dehydrogenase [Fervidobacterium nodosum
Rt17-B1]
Length = 508
Score = 365 bits (936), Expect = 5e-99, Method: Composition-based stats.
Identities = 208/479 (43%), Positives = 299/479 (62%), Gaps = 15/479 (3%)
Query: 12 GLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAREGG 71
LT+DDVL++PQ+S V + + +TRL+R +KL+IP+V++ MDTV E +A A+AREGG
Sbjct: 29 ALTFDDVLLVPQYSEVLP-SDTDVSTRLTRQIKLNIPLVSAAMDTVTESELAKALAREGG 87
Query: 72 IGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXXXX 131
IGI+H+ SI+EQ + VKR ++ +IE+P +I P++T N
Sbjct: 88 IGIIHKNLSIKEQAHQVEIVKRTENGVIENPVVIHPNDTI------FNALKLMAEYKIGG 141
Query: 132 XXNCKNERKLLGIITRHDLKL-ADESTTVESLMTPVDKMVVSTNTSISLEEVTHLMRKGR 190
+E L+G++T D++ +D S V+ LMTP +K+VV+ ISLE+ ++ + R
Sbjct: 142 FPVVDDEGYLVGLLTNRDVRFESDVSKKVKELMTPREKLVVAL-PGISLEKAKQILHEHR 200
Query: 191 TANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIRLVE 250
+PIV +L+ L+T+ DV+ + ++ A+ DS+GRL+VGAAVG KD R LV+
Sbjct: 201 IEKLPIVDDKNKLIGLITIKDVLSVIEHPNAARDSKGRLIVGAAVGTSKDTFERVEALVK 260
Query: 251 AGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXXXKI 310
AG DV+VVD AHGHS I VK++K + K+
Sbjct: 261 AGVDVIVVDTAHGHSKKVIETVKKIK--KMYPDLPVIAGNVATSEAVEELIKAGADAVKV 318
Query: 311 GVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAGADT 370
G+GPGSIC TR+VAG GVPQLSA+L C VA++ +P IADGG+R SGDI KA+ AGA+T
Sbjct: 319 GIGPGSICTTRIVAGIGVPQLSAILQCAYVAKKYDIPIIADGGIRYSGDIVKALAAGAET 378
Query: 371 VMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLS-KAERERTQDEDVFSSLVPEG 429
VMLG++ AGT+E+PG ++ G+K K+ RGM GA S A+R D F VPEG
Sbjct: 379 VMLGSIFAGTEESPGETILYQGRKYKVYRGMGSIGAMKSGSADRYFQSDNQKF---VPEG 435
Query: 430 VEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHGV 488
VEG V KG V +V QL+GGLRSGM Y GAK+I+E+Q++ +F+++T A ++ES H +
Sbjct: 436 VEGMVPYKGAVKDVVYQLIGGLRSGMGYVGAKNIDELQKKAKFIKITNASVKESHPHDI 494
>gi|118195694|gb|ABK78612.1| IMP dehydrogenase/GMP reductase [Cenarchaeum symbiosum A]
Length = 474
Score = 363 bits (933), Expect = 1e-98, Method: Composition-based stats.
Identities = 216/479 (45%), Positives = 298/479 (62%), Gaps = 17/479 (3%)
Query: 12 GLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAREGG 71
GLT+DDVL++P++S +TSR +V+ TRLSRN+ +++P++++NMDTV E MAV MAREGG
Sbjct: 6 GLTFDDVLLVPKYSDITSRSQVDLGTRLSRNISINMPLISANMDTVTESAMAVTMAREGG 65
Query: 72 IGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXXXX 131
IGI+HRF +++EQ + +VKR+ S +IE+P I P +T +A K
Sbjct: 66 IGIIHRFLTMQEQVDEVLKVKRSGSVVIENPYTISPEQTVHDAAAYAEDKGVSGLLVAGP 125
Query: 132 XXNCKNERKLLGIITRHDLKLA-DESTTVESLMTPVDKMVVSTNTSISLEEVTHLMRKGR 190
+ KL+GI+T D++ D S V LMT K VV+ I E LM K R
Sbjct: 126 ------DSKLVGILTERDMEFEEDTSRPVRDLMT---KDVVTAGPDIGPGEARRLMHKNR 176
Query: 191 TANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIRLVE 250
+P+V +G + L+T D+ L AS DS+GR LVGAAVGVK D M R L+
Sbjct: 177 IEKLPLVDGSGTIRGLITSKDITDLENYPGASKDSKGRPLVGAAVGVKDDFMERTDMLLG 236
Query: 251 AGADVLVVDIAHGHSDLCINMVKRLK-GDPRTASVDXXXXXXXXXXXXXXXXXXXXXXXK 309
AGADV+VVDIAHGHS+ ++ V+ +K G P S + K
Sbjct: 237 AGADVIVVDIAHGHSENALSAVRHIKKGFP---SCELIAGNVATARGAEDLIKAGVDAVK 293
Query: 310 IGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAGAD 369
GVG GSICITR+V G+GVPQL+AV+ C +V R +P I+DGG RTSGD +KA+ AGA
Sbjct: 294 TGVGSGSICITRVVTGSGVPQLTAVMDCAKVGRDNDIPVISDGGTRTSGDATKALAAGAS 353
Query: 370 TVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERER--TQDEDVFSSLVP 427
+VM+G+ML GTDE+PG VL K+G++ K+ RGMA GA+L + + + D+D+ + V
Sbjct: 354 SVMVGSMLGGTDESPGSVLTKNGKRFKVYRGMASLGASLGRRSKSPGFSMDDDL-NDYVA 412
Query: 428 EGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSH 486
EGVE V KG V I++QL GG+RSG+SY GA +I +MQ+ F++M+GAG ES H
Sbjct: 413 EGVEAMVPYKGSVNDILKQLTGGIRSGLSYCGAHTIPQMQKNAEFIKMSGAGFAESQPH 471
>gi|154507797|ref|ZP_02043439.1| hypothetical protein ACTODO_00279 [Actinomyces odontolyticus ATCC
17982]
gi|153797431|gb|EDN79851.1| hypothetical protein ACTODO_00279 [Actinomyces odontolyticus ATCC
17982]
Length = 507
Score = 363 bits (931), Expect = 2e-98, Method: Composition-based stats.
Identities = 220/488 (45%), Positives = 294/488 (60%), Gaps = 18/488 (3%)
Query: 11 TGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAREG 70
TGLTYDDVL++P+ + V V+T++RL++N+ L IP++++ MDTV E RMA+AMAR+G
Sbjct: 13 TGLTYDDVLLLPELTDVVP-SSVDTSSRLTKNISLRIPLLSAAMDTVTEARMAIAMARQG 71
Query: 71 GIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXXX 130
GIGILHR SIEEQ A +R+VKR++S ++E P + P T E L+
Sbjct: 72 GIGILHRNLSIEEQAAQVRQVKRSESGMVEDPVTVGPDATIDE----LDSLCGHYRVSGL 127
Query: 131 XXXNCKNERKLLGIITRHDLKLA--DESTT--VESLMTPVDKMVVSTNTSISLEEVTHLM 186
N + LLGIIT DL+ DE T V MTP D++VV IS E HL+
Sbjct: 128 PVVN--EDGTLLGIITNRDLRFVPQDEWATLRVRDCMTPRDQLVVG-QVGISREHAKHLL 184
Query: 187 RKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAI 246
+ R +PIV N L L+T+ D VK + A+ DSRGRL+VGAAVG D RA
Sbjct: 185 AEHRVEKLPIVDDNDHLTGLITVKDFVKTEQYPNATKDSRGRLVVGAAVGYWGDTWERAT 244
Query: 247 RLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXX 306
L EAG DVLVVD A+G + L ++M++R+K DP +D
Sbjct: 245 ALAEAGVDVLVVDTANGGAQLALDMIRRIKDDPTFEGIDIIGGNVATTEGAQALIDAGVD 304
Query: 307 XXKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGA 366
K+GVGPGSIC TR+VAG GVPQ++A+ + GVP IADGGL+ SGDI KA+ A
Sbjct: 305 AVKVGVGPGSICTTRVVAGVGVPQITAIHLAAKACGPAGVPLIADGGLQYSGDIGKALVA 364
Query: 367 GADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDE----DVF 422
GADTVMLG++LAG +E+PG V+ +G++ K RGM GA S+ + ++D DV
Sbjct: 365 GADTVMLGSLLAGCEESPGEVVFTNGKQFKRYRGMGSLGAMSSRGRKSYSKDRYFQADVT 424
Query: 423 S--SLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGL 480
S +VPEG+EG V G + ++ QLVGGL M Y GA +I +++ RFVR+T AGL
Sbjct: 425 SDDKIVPEGIEGQVPYTGSLAQVIYQLVGGLHQTMFYLGASTISQVKANGRFVRITSAGL 484
Query: 481 RESGSHGV 488
RES H V
Sbjct: 485 RESHPHDV 492
>gi|78042653|ref|YP_360021.1| inosine-5'-monophosphate dehydrogenase [Carboxydothermus
hydrogenoformans Z-2901]
gi|77994768|gb|ABB13667.1| inosine-5'-monophosphate dehydrogenase [Carboxydothermus
hydrogenoformans Z-2901]
Length = 483
Score = 362 bits (929), Expect = 3e-98, Method: Composition-based stats.
Identities = 211/485 (43%), Positives = 298/485 (61%), Gaps = 15/485 (3%)
Query: 5 ESASIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAV 64
ES + GLT+DDVL+IP S V R +V+TTTR ++ +KL+IPIV++ MDTV E RMA+
Sbjct: 2 ESKIVKEGLTFDDVLLIPAKSEVLPR-DVDTTTRFTKKIKLNIPIVSAGMDTVTEARMAI 60
Query: 65 AMAREGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXX 124
AMAREGGIG++H+ SIEEQ + +VKR++ +I P + P R+A E +
Sbjct: 61 AMAREGGIGVIHKNMSIEEQAMEVDKVKRSEHGIIADPISLSPEHLIRDALEIMERYHIS 120
Query: 125 XXXXXXXXXNCKNERKLLGIITRHDLKL-ADESTTVESLMTPVDKMVVSTNTSISLEEVT 183
E KL+GIIT DL+ +D S + +MT + + TS L+E
Sbjct: 121 GVPITV-------EGKLVGIITNRDLRFESDYSKKIADVMTKDNLITAPVGTS--LKEAE 171
Query: 184 HLMRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMN 243
+++K + +P+V +N L L+T+ D+ K RK A+ D +GRL V AAVGV +D M+
Sbjct: 172 KILQKHKIEKLPLVDENFHLKGLITIKDIEKTRKYPNAAKDEKGRLRVAAAVGVSRDMMD 231
Query: 244 RAIRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXX 303
R LVEA D +VVD AHGHS + V ++K + V+
Sbjct: 232 RVKALVEAKVDAIVVDTAHGHSRGVLEAVYKIKS--KYPEVELVAGNVATAEATEDLIKA 289
Query: 304 XXXXXKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKA 363
K+G+GPGSIC TR+VAG GVPQ++A+L C VA + VP IADGG++ SGDI+KA
Sbjct: 290 GADAVKVGIGPGSICTTRVVAGIGVPQITAILDCAEVAMKYDVPIIADGGIKYSGDITKA 349
Query: 364 IGAGADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFS 423
+ AGADTVMLG++LAGT+E+PG + + G+ K+ RGM GA + + ++R E+
Sbjct: 350 LAAGADTVMLGSLLAGTEESPGEIEIWQGRSYKVYRGMGSLGA-MKEGSKDRYFQENE-Q 407
Query: 424 SLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRES 483
LVPEGVEG V KGPV + QL+GGLR+GM Y G ++I E++ +T+F+++T AGLRES
Sbjct: 408 KLVPEGVEGRVPFKGPVSETIFQLIGGLRAGMGYCGVRNIYELKTKTKFIKITQAGLRES 467
Query: 484 GSHGV 488
H V
Sbjct: 468 HPHDV 472
>gi|161529077|ref|YP_001582903.1| inosine-5'-monophosphate dehydrogenase [Nitrosopumilus maritimus
SCM1]
gi|160340378|gb|ABX13465.1| inosine-5'-monophosphate dehydrogenase [Nitrosopumilus maritimus
SCM1]
Length = 476
Score = 362 bits (929), Expect = 4e-98, Method: Composition-based stats.
Identities = 208/479 (43%), Positives = 295/479 (61%), Gaps = 13/479 (2%)
Query: 12 GLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAREGG 71
GLT+DDVL++P++S +TSR + + TT+LSRN+ ++IP V++NMDTV E MAVAMAR GG
Sbjct: 6 GLTFDDVLLVPKYSDITSRSQTDLTTKLSRNITINIPFVSANMDTVTESSMAVAMARAGG 65
Query: 72 IGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXXXX 131
IGI+HRF +I+EQ + +VKR+ S +IE+P I ++ ++A + K
Sbjct: 66 IGIIHRFLTIQEQANEVLKVKRSGSVMIENPYSISSDKSIQDALDYAEDKEISGLLVV-- 123
Query: 132 XXNCKNERKLLGIITRHDLKLADESTTVESLMTPVDKMVVSTNTSISLEEVTHLMRKGRT 191
+ KL+GI+T DL A + T+ +MT K VV+ +SL+E ++ K R
Sbjct: 124 ----DSNSKLVGIVTERDLLFAGSNGTIADVMT---KDVVTAKPGVSLDEAKDILHKHRI 176
Query: 192 ANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIRLVEA 251
+PIV +G + L+T D+ AS D +GR LVGAAVGVK D + R+ L+ A
Sbjct: 177 EKLPIVDDSGIIQGLITSKDITNNTDYPNASKDKKGRPLVGAAVGVKGDFLERSESLLNA 236
Query: 252 GADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXXXKIG 311
GADVLVVDIAHGHS+ I+ V+ +K + K+G
Sbjct: 237 GADVLVVDIAHGHSENAISTVRNIK--KAFPDCELIAGNIATAQGAEDLIKAGVDAVKVG 294
Query: 312 VGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAGADTV 371
VG GSICITR++ G+GVPQL+AV+ C ++ G+P I+DGG RTSGD +KA+ AGA +V
Sbjct: 295 VGSGSICITRVITGSGVPQLTAVMDCAKIGNDHGIPIISDGGTRTSGDATKALAAGASSV 354
Query: 372 MLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERE--RTQDEDVFSSLVPEG 429
M+G+ML GTDE+PG VL K+G++ K+ RGMA A++ + +E ED + V EG
Sbjct: 355 MVGSMLGGTDESPGTVLTKNGKRFKVYRGMASLAASIGRKSKETGSISLEDDLNDYVAEG 414
Query: 430 VEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHGV 488
VE V KG V I++QL GG+RSG+SY GA +I +MQ+ F++M+ AG ES H V
Sbjct: 415 VEAMVPYKGTVTDILKQLAGGVRSGLSYCGAHTIPQMQQNAEFIKMSRAGFAESQPHDV 473
>gi|114566449|ref|YP_753603.1| IMP dehydrogenase [Syntrophomonas wolfei subsp. wolfei str.
Goettingen]
gi|114337384|gb|ABI68232.1| inosine-5'-monophosphate dehydrogenase [Syntrophomonas wolfei
subsp. wolfei str. Goettingen]
Length = 484
Score = 361 bits (927), Expect = 7e-98, Method: Composition-based stats.
Identities = 207/479 (43%), Positives = 293/479 (61%), Gaps = 15/479 (3%)
Query: 12 GLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAREGG 71
GLT+DDVL++P S V ++V+ +T LSRN++L IPI+++ MDTV E RMA+A+AREGG
Sbjct: 9 GLTFDDVLLVPGRSEVLP-QDVDVSTMLSRNIRLVIPILSAGMDTVTETRMAIAVAREGG 67
Query: 72 IGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXXXX 131
IGI+H+ SIEEQ M+ VKR++ +I P + P R+A + +
Sbjct: 68 IGIIHKNMSIEEQARMVDRVKRSEHGIITDPFFLSPDNIIRDALDIMEHYHISGVPITEG 127
Query: 132 XXNCKNERKLLGIITRHDLKL-ADESTTVESLMTPVDKMVVSTNTSISLEEVTHLMRKGR 190
KL+GIIT D++ D + ++++MT + +V+ S+++ L+RK +
Sbjct: 128 S-------KLVGIITNRDIRFETDFNQPIKNVMT--SEGLVTAPVGTSMDQAMDLLRKYK 178
Query: 191 TANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIRLVE 250
+P+V + L+ L+T+ D+ K K A+ D RGRLLVGAAVG+ D + R L +
Sbjct: 179 IEKLPLVDDSFNLMGLITIKDIEKTSKYPNAAKDQRGRLLVGAAVGIAHDTLERVECLKK 238
Query: 251 AGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXXXKI 310
AGADV+VVD AHGHS I MV +K + ++ K+
Sbjct: 239 AGADVIVVDTAHGHSLSVIRMVATIK--KQFPDIELIAGNVATAEATEELIKVGADAIKV 296
Query: 311 GVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAGADT 370
G+GPGSIC TR+VAG GVPQ++AV C +VA++ VP IADGG++ SGDI+KAI AGADT
Sbjct: 297 GIGPGSICTTRVVAGIGVPQITAVFDCAQVAKKHNVPIIADGGIKYSGDIAKAIAAGADT 356
Query: 371 VMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFSSLVPEGV 430
VMLGN+LAGTDE+PG + G+ K+ RGM GA + + +R ED LVPEG+
Sbjct: 357 VMLGNLLAGTDESPGETQIYQGRSYKVYRGMGSLGA-MVQGSSDRYFQEDA-HKLVPEGI 414
Query: 431 EGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHGVA 489
EG + KG V + QL+GGL++GM Y G K IEEMQ +T F+R+T AGL ES H ++
Sbjct: 415 EGRIPYKGYVSETIFQLIGGLKAGMGYCGVKDIEEMQSKTNFIRITNAGLIESHPHDIS 473
>gi|121535780|ref|ZP_01667581.1| inosine-5'-monophosphate dehydrogenase [Thermosinus carboxydivorans
Nor1]
gi|121305612|gb|EAX46553.1| inosine-5'-monophosphate dehydrogenase [Thermosinus carboxydivorans
Nor1]
Length = 484
Score = 360 bits (924), Expect = 1e-97, Method: Composition-based stats.
Identities = 202/480 (42%), Positives = 298/480 (62%), Gaps = 15/480 (3%)
Query: 10 PTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMARE 69
P GLT+DDVL+IP S V R EV+ +T L+RN+KL+IPI++S MDTV E RMA+AMARE
Sbjct: 8 PEGLTFDDVLLIPAKSDVLPR-EVDVSTNLTRNIKLNIPIISSGMDTVTEARMAIAMARE 66
Query: 70 GGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXX 129
GG+G++H+ SIE Q + +VKR++ +I P + P T ++A + +
Sbjct: 67 GGLGVIHKNMSIERQANEIDKVKRSEHGIIVDPIFLSPENTLQDAHDLME-------KYR 119
Query: 130 XXXXNCKNERKLLGIITRHDLKL-ADESTTVESLMTPVDKMVVSTNTSISLEEVTHLMRK 188
++ KL+GI+T DL+ D + MT + +++ SLE+ ++R+
Sbjct: 120 ISGVPVTDKGKLVGILTNRDLRFETDLRRKIRECMT--HEHLITAPVGTSLEQAKEILRQ 177
Query: 189 GRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIRL 248
R +P+V ++G L L+T+ D+ K +K ++ D++GRLLV AAVGV D M+R +
Sbjct: 178 HRIEKLPLVDEHGNLKGLITIKDIEKAQKYPNSAKDNKGRLLVAAAVGVGADMMDRVDAI 237
Query: 249 VEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXXX 308
V A DV+V+D AHGHS + VK++K ++D
Sbjct: 238 VAAKVDVIVIDTAHGHSRGVLEAVKKIK--QAYPNIDLIAGNVATAEATRDLIEAGADAV 295
Query: 309 KIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAGA 368
K+G+GPGSIC TR++AG GVPQ++A+ C R AR VP IADGG++ SGDI+KAI AGA
Sbjct: 296 KVGIGPGSICTTRVIAGIGVPQITAIYDCARAAREYKVPIIADGGIKYSGDITKAIAAGA 355
Query: 369 DTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFSSLVPE 428
VM+GN+LAGT+E+PG +++ G+ K+ RGM GA +++ ++R E++ LVPE
Sbjct: 356 HVVMIGNLLAGTEESPGEMIIYQGRSYKVYRGMGSLGA-MAEGSKDRYFQENM-DKLVPE 413
Query: 429 GVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHGV 488
G+EG V KG V V QLVGGL++GM Y G ++IEE+ +TRF+R+TGAGL+ES H +
Sbjct: 414 GIEGRVPYKGSVADTVFQLVGGLKAGMGYCGVRNIEELINKTRFIRITGAGLKESHPHDI 473
>gi|50843228|ref|YP_056455.1| IMP dehydrogenase / GMP reductase [Propionibacterium acnes
KPA171202]
gi|50840830|gb|AAT83497.1| IMP dehydrogenase / GMP reductase [Propionibacterium acnes
KPA171202]
Length = 504
Score = 360 bits (923), Expect = 2e-97, Method: Composition-based stats.
Identities = 209/487 (42%), Positives = 295/487 (60%), Gaps = 17/487 (3%)
Query: 10 PTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMARE 69
P LT+DDVL+ P S V +V TTTR+SRN+ ++IP+V++ MDTV E RMAVAMARE
Sbjct: 15 PLALTFDDVLLQPVESNVIP-SQVKTTTRVSRNISIAIPLVSAAMDTVTETRMAVAMARE 73
Query: 70 GGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXX 129
GG+GILHR SIE+Q AM+ +VKR+++ +I+ P I P+ T +A E +
Sbjct: 74 GGLGILHRNLSIEDQAAMVDQVKRSEAGMIDEPITISPNATLADAEELCHTYRISGVPVV 133
Query: 130 XXXXNCKNERKLLGIITRHDLKLADE-STTVESLMTPVDKMVVSTNTSISLEEVTHLMRK 188
N L+GIIT D++ D + +MT + TS S + L+
Sbjct: 134 DDKEN------LVGIITNRDMRFEDNPQRPICEVMTAAPLVTAPVGTSPS--DALSLLAA 185
Query: 189 GRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIRL 248
+ +P+V +G+L L TL D VK K A+ D +GRL VGAA+G + +RA+ L
Sbjct: 186 HKIEKLPLVDADGKLRGLFTLKDFVKTDKYPNATKDPQGRLRVGAAIGFFGNSWDRAMAL 245
Query: 249 VEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXXX 308
VE G D++VVD AHGH+ +M+ RLK +P VD
Sbjct: 246 VEEGVDLIVVDTAHGHTQGVFDMIARLKAEPAAQGVDVVAGNIATYEAAKALCAAGVDGI 305
Query: 309 KIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAGA 368
K+G+GPGSIC TR+VAG GVPQ++A+ ++ AR+ VP I DGGL+ SGDI+KA+ AGA
Sbjct: 306 KVGIGPGSICTTRVVAGVGVPQVTAIFEASKAARQYDVPVIGDGGLQYSGDIAKALVAGA 365
Query: 369 DTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAE-----RERTQDEDVFS 423
D+VMLG++LAG +E+PG + +G++ K RGM GA ++ E ++R DV +
Sbjct: 366 DSVMLGSLLAGCEESPGELAFINGKQFKTYRGMGSMGAMSARGEKLSYSKDRYFQGDVTT 425
Query: 424 S--LVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLR 481
+ +VPEG+EG VA +GP+G + QLVGGLR M Y+GA++I+E+ R RFVR+T AGLR
Sbjct: 426 NDKIVPEGIEGQVAYRGPLGAVAYQLVGGLRQSMFYTGARTIDELHERGRFVRITSAGLR 485
Query: 482 ESGSHGV 488
ES H +
Sbjct: 486 ESHPHDI 492
>gi|15607007|ref|NP_214389.1| inosine monophosphate dehydrogenase [Aquifex aeolicus VF5]
gi|6016372|sp|O67820|IMDH_AQUAE Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH)
(IMPD)
gi|2984252|gb|AAC07779.1| inosine monophosphate dehydrogenase [Aquifex aeolicus VF5]
Length = 490
Score = 360 bits (923), Expect = 2e-97, Method: Composition-based stats.
Identities = 208/483 (43%), Positives = 292/483 (60%), Gaps = 15/483 (3%)
Query: 9 IPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAR 68
I GLT+DDVL++PQ+S V EV+ +T L++ +KL+IPIV++ MDTV E R+A+A+AR
Sbjct: 8 IKEGLTFDDVLLVPQYSEVLPH-EVDVSTYLTKRIKLNIPIVSAAMDTVTEARLAIALAR 66
Query: 69 EGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXX 128
EGGIGI+HR I++Q + +VK+++S +I +P + P +EA + +
Sbjct: 67 EGGIGIIHRNLPIKKQAEEVEKVKKSESGMIINPVTVKPDTRVKEALDIM------AKYK 120
Query: 129 XXXXXNCKNERKLLGIITRHDLKL---ADESTTVESLMTPVDKMVVSTNTSISLEEVTHL 185
ERKL+GI+T DL+ D S V MT + +++ I+L+E +
Sbjct: 121 ISGVPVVDEERKLIGILTNRDLRFIKPEDYSKPVSEFMT--KENLITAPEGITLDEAEEI 178
Query: 186 MRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRA 245
RK + +PIV + G++ L+T+ D+VK +K A D GRL VGAAVG ++ ++R
Sbjct: 179 FRKYKIEKLPIVDKEGKIKGLITIKDIVKRKKYPNACKDELGRLRVGAAVGTGEETLDRV 238
Query: 246 IRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXX 305
LVEAG DV+VVD AHGHS + V+++K + VD
Sbjct: 239 AALVEAGVDVIVVDTAHGHSKRVLETVEKIKAN--FPEVDVIAGNVATAEGTKALIEAGA 296
Query: 306 XXXKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIG 365
K+GVGPGSIC TR+VAG GVPQL+A++ AR +P IADGG+R SGDI KA+
Sbjct: 297 DAVKVGVGPGSICTTRIVAGVGVPQLTAIMEAASAAREYDIPIIADGGIRYSGDIVKALA 356
Query: 366 AGADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFSSL 425
AGA VMLGN+LAGT+EAPG + G+ K+ RGM GA S+ +R E +
Sbjct: 357 AGASAVMLGNLLAGTEEAPGETIYYQGRAYKVYRGMGSLGAMSSRLSSDRYGQEKM-EKF 415
Query: 426 VPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGS 485
VPEG+EG V KG + +V QLVGGLRSGM Y GA++I+E+Q + +FVR+T AG RES
Sbjct: 416 VPEGIEGRVPYKGKLADVVYQLVGGLRSGMGYVGARNIKELQEKAKFVRITWAGYRESHV 475
Query: 486 HGV 488
H V
Sbjct: 476 HDV 478
>gi|146296720|ref|YP_001180491.1| inosine-5'-monophosphate dehydrogenase [Caldicellulosiruptor
saccharolyticus DSM 8903]
gi|145410296|gb|ABP67300.1| inosine-5'-monophosphate dehydrogenase [Caldicellulosiruptor
saccharolyticus DSM 8903]
Length = 488
Score = 358 bits (919), Expect = 5e-97, Method: Composition-based stats.
Identities = 205/489 (41%), Positives = 297/489 (60%), Gaps = 16/489 (3%)
Query: 1 MSFNESASIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQ 60
M F + I LT+DDVL++PQ+S V K+V+ +T L+R +KL+IP++++ MDTV E
Sbjct: 1 MGFKDKV-IKEALTFDDVLLVPQYSEVLP-KDVDVSTYLTRTIKLNIPLMSAGMDTVTES 58
Query: 61 RMAVAMAREGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNW 120
RMA+A+AREGGIG++H+ +IEEQ + + +VKR++ +I P + P EA E +
Sbjct: 59 RMAIAIAREGGIGVIHKNMTIEEQASEVDKVKRSEHGVIVDPFYLSPENKIYEAMELM-- 116
Query: 121 KXXXXXXXXXXXXNCKNERKLLGIITRHDLKL-ADESTTVESLMTPVDKMVVSTNTSISL 179
KL+GIIT D++ D S ++ +MT + +++ I+L
Sbjct: 117 -----AKYRISGVPITVNGKLVGIITNRDIRFETDYSKPIKEVMTSSN--LITAKEGITL 169
Query: 180 EEVTHLMRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKK 239
EE +M+K + +PIV G L L+T+ D+ K K A+ DSRGRLL AAVGV K
Sbjct: 170 EEAKEIMKKHKIEKLPIVDDEGNLKGLITIKDIEKAVKYPNAAKDSRGRLLCAAAVGVSK 229
Query: 240 DDMNRAIRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXX 299
D R LV+A DV+VVD AHGHS I VK++K + ++
Sbjct: 230 DTEQRVEALVKAQVDVIVVDTAHGHSKGVIETVKKIKA--KYPNLQVVAGNIATAEAAYD 287
Query: 300 XXXXXXXXXKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGD 359
K+G+GPGSIC TR+VAG GVPQ++A++ C VA+ G+P IADGG+R SGD
Sbjct: 288 LIKAGADCIKVGIGPGSICTTRVVAGVGVPQITAIMDCAEVAKEYGIPVIADGGIRYSGD 347
Query: 360 ISKAIGAGADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDE 419
I+KA+ AGAD VM+G++ AG +E+PG + G++ K+ RGM A + ++R E
Sbjct: 348 ITKALAAGADVVMIGSLFAGCEESPGECEIYQGRRFKVYRGMGSLSA-MKAGSKDRYFQE 406
Query: 420 DVFSSLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAG 479
D S LVPEGVEG V KGP+ V QLVGGL++GM Y GA++I+E+Q + +FV++T AG
Sbjct: 407 DA-SKLVPEGVEGRVPYKGPLEDTVFQLVGGLKAGMGYCGARTIKELQEKAKFVKITQAG 465
Query: 480 LRESGSHGV 488
+RES H +
Sbjct: 466 VRESHPHDI 474
>gi|163782022|ref|ZP_02177021.1| inosine monophosphate dehydrogenase [Hydrogenivirga sp. 128-5-R1-1]
gi|159882554|gb|EDP76059.1| inosine monophosphate dehydrogenase [Hydrogenivirga sp. 128-5-R1-1]
Length = 490
Score = 356 bits (914), Expect = 2e-96, Method: Composition-based stats.
Identities = 204/480 (42%), Positives = 290/480 (60%), Gaps = 15/480 (3%)
Query: 12 GLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAREGG 71
GLT+DDVL++P +S V EV+ +T ++R ++L+IPIV++ MDTV E R+A+A+AREGG
Sbjct: 11 GLTFDDVLLVPDYSEVLPH-EVDVSTYITRKIRLNIPIVSAAMDTVTEARLAIALAREGG 69
Query: 72 IGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXXXX 131
+G++HR I EQ + +VK+++S +I +P + P + REA E +
Sbjct: 70 LGVIHRNMPIGEQAREVEKVKKSESGMILNPVTVRPEASVREALEIMERYKISGVPVV-- 127
Query: 132 XXNCKNERKLLGIITRHDLKL---ADESTTVESLMTPVDKMVVSTNTSISLEEVTHLMRK 188
E KL+GI+T DL+ +D V MT + +V+ I L+E T L++K
Sbjct: 128 ----DEEEKLVGILTNRDLRFIKPSDYDKPVTQFMT--KENLVTAEEGIGLDEATELLQK 181
Query: 189 GRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIRL 248
+ +PIV G++ L+T+ D+VK ++ A D GRL VGAAVG +D ++R L
Sbjct: 182 FKVEKLPIVDSEGRIKGLITIKDIVKRKQYPNACKDEIGRLRVGAAVGTGEDALDRVSAL 241
Query: 249 VEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXXX 308
VEAG D++VVD AHGHS + V ++K R +
Sbjct: 242 VEAGVDLIVVDTAHGHSKRVLETVSKVKA--RFPELQVVAGNVATAEGTKALIEAGADAV 299
Query: 309 KIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAGA 368
KIGVGPGSIC TR+VAG GVPQ+SA++ VAR +P IADGG+R SGDI KA+ AGA
Sbjct: 300 KIGVGPGSICTTRIVAGVGVPQISAIMDAYSVAREEDIPVIADGGIRYSGDIVKALAAGA 359
Query: 369 DTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFSSLVPE 428
+ VMLGN+LAGT+EAPG + G+ K+ RGM GA +S+ +R +D VPE
Sbjct: 360 NVVMLGNLLAGTEEAPGETIYYQGRAYKVYRGMGSLGAMVSRHSSDR-YGQDKLEKFVPE 418
Query: 429 GVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHGV 488
G+EG V KG + I+ QLVGGLRSGM Y+G ++++E+Q + +FVR+T AG RES H V
Sbjct: 419 GIEGRVPYKGRLSEIIYQLVGGLRSGMGYTGCRTVKELQEKAKFVRITWAGYRESHVHDV 478
>gi|150021453|ref|YP_001306807.1| inosine-5'-monophosphate dehydrogenase [Thermosipho melanesiensis
BI429]
gi|149793974|gb|ABR31422.1| inosine-5'-monophosphate dehydrogenase [Thermosipho melanesiensis
BI429]
Length = 483
Score = 353 bits (906), Expect = 1e-95, Method: Composition-based stats.
Identities = 198/478 (41%), Positives = 294/478 (61%), Gaps = 13/478 (2%)
Query: 12 GLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAREGG 71
LT+DDVL++P +S + EV+ TRL++ + L+IP+V++ MDTV E +A A+AREGG
Sbjct: 4 ALTFDDVLLVPGYSEILP-GEVDVKTRLTKQITLNIPLVSAAMDTVTESELAKAIAREGG 62
Query: 72 IGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXXXX 131
IGI+H+ SIEEQ ++ VKR ++ +I+ P + P + EA +
Sbjct: 63 IGIIHKNLSIEEQAHQVKIVKRTENGIIDDPVTVFPDVSVEEA------EKIMAEYKIGG 116
Query: 132 XXNCKNERKLLGIITRHDLKLA-DESTTVESLMTPVDKMVVSTNTSISLEEVTHLMRKGR 190
+++LLG++T D++ + V+ LMTPV+ ++V+ N ISLEE ++ + +
Sbjct: 117 LPVVDEQKRLLGLVTNRDIRFERNLKRPVKELMTPVEDLIVA-NEGISLEEARDILHENK 175
Query: 191 TANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIRLVE 250
+P+V +G L L+T+ D+ + ++ AS D +GRLLVGAAVG +D ++R LV+
Sbjct: 176 IEKLPLVKSDGTLSGLITIKDIRSVVEHPNASRDKKGRLLVGAAVGTSEDTLDRVENLVK 235
Query: 251 AGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXXXKI 310
AG DV+VVD AHGHS I VK +K ++ K+
Sbjct: 236 AGVDVIVVDTAHGHSKKVIETVKMIK--EHFPNIPVIAGNIATSEATEALIKVGADAVKV 293
Query: 311 GVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAGADT 370
G+GPGSIC TR+VAG GVPQL+A+ C VA++ +P IADGG+R SGDI KA+ AGA+T
Sbjct: 294 GIGPGSICTTRIVAGIGVPQLTAIFDCVEVAKKYDIPIIADGGIRFSGDIVKALAAGAET 353
Query: 371 VMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFSSLVPEGV 430
VMLG++ AGT+EAPG ++ G+K K RGM GA +S+ +R + +PEGV
Sbjct: 354 VMLGSIFAGTEEAPGETILYQGRKYKSYRGMGSLGA-MSRGSADRYFQSNN-QKFIPEGV 411
Query: 431 EGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHGV 488
EG V KG V +V QL+GGLRSGM Y GA++I+E+QR+ +F+R+T A ++ES H +
Sbjct: 412 EGMVPYKGSVKDVVYQLIGGLRSGMGYVGAENIKELQRKAKFIRITAASVKESHPHDI 469
>gi|119717867|ref|YP_924832.1| inosine-5'-monophosphate dehydrogenase [Nocardioides sp. JS614]
gi|119538528|gb|ABL83145.1| inosine-5'-monophosphate dehydrogenase [Nocardioides sp. JS614]
Length = 500
Score = 353 bits (906), Expect = 2e-95, Method: Composition-based stats.
Identities = 208/487 (42%), Positives = 292/487 (59%), Gaps = 19/487 (3%)
Query: 12 GLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAREGG 71
GLTYDDVL++P HS + +++ T+RL+R + L +P+V++ MDTV E RMA+AMAR+GG
Sbjct: 11 GLTYDDVLLLPGHSDLAP-ADIDMTSRLTREISLKVPLVSAAMDTVTESRMAIAMARQGG 69
Query: 72 IGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXXXX 131
+G+LHR SIE+Q + VKR Q+ +I +P I P T E L+
Sbjct: 70 LGVLHRNLSIEDQAYQVDLVKRTQTGIISNPVTIGPDATL----EQLDQLAGEYRISGFP 125
Query: 132 XXNCKNERKLLGIITRHDLKLAD----ESTTVESLMTPVDKMVVSTNTSISLEEVTHLMR 187
+ N +LLGIIT DL+ +T V+ +MTP+ +++ IS E+ T L+R
Sbjct: 126 VVDADN--RLLGIITNRDLRFTPVAEWATTKVDEVMTPMP--LITAPPDISREDATLLLR 181
Query: 188 KGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIR 247
+ + +P+V G+L L+T+ D VK + AS D GRL+VGAA+G D RA
Sbjct: 182 QHKRERLPLVDAQGRLAGLITVKDFVKSEQFPHASKDGAGRLMVGAAIGYFGDAWQRATT 241
Query: 248 LVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXX 307
LVEAG DVLV D AHGH L ++MV+RLK DP T V
Sbjct: 242 LVEAGVDVLVADTAHGHVTLLLDMVRRLKADPATRHVQVIGGNVATRDGAQAFVDAGADA 301
Query: 308 XKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAG 367
K+G GPGSIC TR+V G GVPQ++AV + + GVP IADGGL+ SGDI+KAI AG
Sbjct: 302 VKVGFGPGSICTTRVVTGCGVPQITAVYEASLACQPVGVPVIADGGLQQSGDIAKAIVAG 361
Query: 368 ADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDE----DVFS 423
A+TVM+G++LAG +E+PG ++ +G++ K RGM A S+ ++ ++D +V S
Sbjct: 362 AETVMIGSLLAGCEESPGELIFVNGKQYKSYRGMGSLAAMSSRGKKSYSKDRYFQAEVTS 421
Query: 424 --SLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLR 481
+VPEG+EG VA +GP+ + QL+GGL M Y GA +I E+Q + RFVR+T A L+
Sbjct: 422 DDKIVPEGIEGQVAYRGPLAAVAHQLIGGLNQSMFYIGAATIPELQAKGRFVRITSASLK 481
Query: 482 ESGSHGV 488
ES H V
Sbjct: 482 ESHPHDV 488
>gi|138893688|ref|YP_001124141.1| inositol-5-monophosphate dehydrogenase [Geobacillus
thermodenitrificans NG80-2]
gi|134265201|gb|ABO65396.1| Inosine-monophosphate dehydrogenase [Geobacillus
thermodenitrificans NG80-2]
Length = 488
Score = 352 bits (902), Expect = 5e-95, Method: Composition-based stats.
Identities = 202/478 (42%), Positives = 296/478 (61%), Gaps = 12/478 (2%)
Query: 12 GLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAREGG 71
GLT+DDVL+IP S V R +V+ TTRLS ++L+IPI+++ MDTV E MA+AMAR+GG
Sbjct: 10 GLTFDDVLLIPAKSDVLPR-DVDVTTRLSDTLQLNIPIISAGMDTVTEAEMAIAMARQGG 68
Query: 72 IGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXXXX 131
+GI+H+ SIE+Q + +VKR++ +I P + P +A E L K
Sbjct: 69 LGIIHKNMSIEQQAEQVDKVKRSERGVITDPFFLTPDHQVYDA-EHLMGKYRISGVPIV- 126
Query: 132 XXNCKNERKLLGIITRHDLK-LADESTTVESLMTPVDKMVVSTNTSISLEEVTHLMRKGR 190
N E+KL+GIIT DL+ + D S + +MT + + T+ LEE ++++ +
Sbjct: 127 --NNAEEQKLVGIITNRDLRFIQDYSIKISEVMTKENLITAPVGTT--LEEAEKILQQHK 182
Query: 191 TANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIRLVE 250
+P+V +NG L L+T+ D+ K+ + ++ D++GRL+VGAAVGV D M R +LVE
Sbjct: 183 VEKLPLVDENGILKGLITIKDIEKVIEFPNSAKDAKGRLVVGAAVGVTADTMIRVKKLVE 242
Query: 251 AGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXXXKI 310
AG DV+VVD AHGHS + V ++ + ++ K+
Sbjct: 243 AGVDVIVVDTAHGHSKGVLETVANIR--RQYPDLNIIAGNVATAEATRDLIEAGANIIKV 300
Query: 311 GVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAGADT 370
G+GPGSIC TR+VAG GVPQ++A+ C AR+ GVP IADGG++ SGDI KA+ AGA
Sbjct: 301 GIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGVPIIADGGIKYSGDIVKAMAAGAHA 360
Query: 371 VMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFSSLVPEGV 430
VMLG++LAG E+PG + G++ K+ RGM G A++ + ++R E+ VPEG+
Sbjct: 361 VMLGSLLAGVSESPGETEIYQGRRFKVYRGM-GSVASMERGSKDRYFQEEA-KKFVPEGI 418
Query: 431 EGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHGV 488
EG V KGP+ + QLVGGLR+GM Y G ++++E++ +T+F+RMTGAGLRES H V
Sbjct: 419 EGRVPYKGPLADTIYQLVGGLRAGMGYCGTRNLDELREKTQFIRMTGAGLRESHPHDV 476
>gi|56418544|ref|YP_145862.1| inositol-5-monophosphate dehydrogenase [Geobacillus kaustophilus
HTA426]
gi|56378386|dbj|BAD74294.1| inositol-monophosphate dehydrogenase [Geobacillus kaustophilus
HTA426]
Length = 488
Score = 351 bits (901), Expect = 7e-95, Method: Composition-based stats.
Identities = 202/478 (42%), Positives = 293/478 (61%), Gaps = 12/478 (2%)
Query: 12 GLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAREGG 71
GLT+DDVL+IP S V R +V+ TT+LS ++L+IPI+++ MDTV E MA+AMAR+GG
Sbjct: 10 GLTFDDVLLIPAKSDVLPR-DVDVTTKLSDTLQLNIPILSAGMDTVTEAEMAIAMARQGG 68
Query: 72 IGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXXXXX 131
+GI+H+ SIE+Q + +VKR++ +I P + P +A E L K
Sbjct: 69 LGIIHKNMSIEQQAEQVDKVKRSERGVITDPFFLTPDHQVYDA-EHLMSKYRISGVPIV- 126
Query: 132 XXNCKNERKLLGIITRHDLK-LADESTTVESLMTPVDKMVVSTNTSISLEEVTHLMRKGR 190
N E+KL+GIIT DL+ + D S + +MT + + T+ LEE ++++ +
Sbjct: 127 --NNPEEQKLVGIITNRDLRFIQDYSIKISEVMTKENLITAPVGTT--LEEAEKILQRHK 182
Query: 191 TANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIRLVE 250
+P+V +NG L L+T+ D+ K+ + ++ D++GRL+VGAAVGV D M R +LVE
Sbjct: 183 VEKLPLVDENGVLKGLITIKDIEKVIEFPNSAKDAKGRLIVGAAVGVTADTMIRVKKLVE 242
Query: 251 AGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXXXKI 310
AG DV+VVD AHGHS + V ++ + ++ K+
Sbjct: 243 AGVDVIVVDTAHGHSKGVLETVANIR--RQYPDLNIIAGNVATAEGTRDLIEAGANIIKV 300
Query: 311 GVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAGADT 370
G+GPGSIC TR+VAG GVPQ++A+ C AR+ GVP IADGG++ SGDI KAI AGA
Sbjct: 301 GIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGVPIIADGGIKYSGDIVKAIAAGAHA 360
Query: 371 VMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFSSLVPEGV 430
VMLG++LAG E+PG + G++ K+ RGM A + + ++R ED VPEG+
Sbjct: 361 VMLGSLLAGVSESPGETEIYQGRRFKVYRGMGSVAA-MERGSKDRYFQEDA-KKFVPEGI 418
Query: 431 EGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHGV 488
EG V KGP+ + QLVGGLR+GM Y G +++EE++ +T+F+RMT AGLRES H V
Sbjct: 419 EGRVPYKGPLADTIYQLVGGLRAGMGYCGTRNLEELREKTQFIRMTSAGLRESHPHDV 476
>gi|89211833|ref|ZP_01190168.1| IMP dehydrogenase [Halothermothrix orenii H 168]
gi|89158560|gb|EAR78273.1| IMP dehydrogenase [Halothermothrix orenii H 168]
Length = 486
Score = 351 bits (900), Expect = 9e-95, Method: Composition-based stats.
Identities = 202/481 (41%), Positives = 291/481 (60%), Gaps = 12/481 (2%)
Query: 9 IPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAVAMAR 68
+ GLT+DDVL+IP S V R +V T TRL++N+ L+IPI+++ MDTV E R+A+AMAR
Sbjct: 5 VKEGLTFDDVLLIPARSEVLPR-DVETRTRLTKNINLNIPIMSAGMDTVTEARLAIAMAR 63
Query: 69 EGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXXXXXX 128
+GGIGI+H+ SI Q + VKR++S +I P + P EA E L K
Sbjct: 64 QGGIGIIHKNMSIGRQAEEVDRVKRSESGVIVDPFYLKPDNLIVEA-EALMSKFKISGVP 122
Query: 129 XXXXXNCKNERKLLGIITRHDLKLA-DESTTVESLMTPVDKMVVSTNTSISLEEVTHLMR 187
RKL+GIIT DL+ D + + +MT D+ +V+ ++E+ +++
Sbjct: 123 IV-----DENRKLVGIITNRDLRFVKDYNRPIHEVMT--DEDLVTAPVGTTIEQAKEILQ 175
Query: 188 KGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMNRAIR 247
+ + +P+V +N L L+T+ D+ K + A+ D RGRL+VGAAVG+ D +R
Sbjct: 176 EHKIEKLPLVDENNILKGLITIKDIEKAEEFPHAAKDERGRLIVGAAVGISDDTDDRVAA 235
Query: 248 LVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXXXXXX 307
LV+AG DV+V+D AHGHS + V+R+KG+ V
Sbjct: 236 LVKAGVDVIVIDTAHGHSVGVLKTVERIKGN--YPDVPVIAGNVATAEATEDLIKAGADV 293
Query: 308 XKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKAIGAG 367
K+GVGPGSIC TR++AG GVPQ++A+ C A+ G+P IADGG++ SGDI KA+ AG
Sbjct: 294 VKVGVGPGSICTTRVIAGVGVPQITAIYDCAEKAKEYGIPVIADGGIKYSGDIVKALVAG 353
Query: 368 ADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFSSLVP 427
AD VM+G++LAGT+E+PG + + G+ K+ RGM GA ++ Q+E LVP
Sbjct: 354 ADVVMIGSLLAGTEESPGELEIYKGRSYKVYRGMGSLGAMQQGSKDRYFQNESDVKKLVP 413
Query: 428 EGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRESGSHG 487
EG+EG V +GP+ + QLVGGLR+GM Y GA++I E+Q + +FVR+T AGLRES H
Sbjct: 414 EGIEGRVPYRGPLSETIYQLVGGLRAGMGYCGARTISELQEKGKFVRITSAGLRESHPHD 473
Query: 488 V 488
V
Sbjct: 474 V 474
>gi|152973862|ref|YP_001373379.1| inosine-5'-monophosphate dehydrogenase [Bacillus cereus subsp.
cytotoxis NVH 391-98]
gi|152022614|gb|ABS20384.1| inosine-5'-monophosphate dehydrogenase [Bacillus cereus subsp.
cytotoxis NVH 391-98]
Length = 487
Score = 350 bits (897), Expect = 2e-94, Method: Composition-based stats.
Identities = 205/485 (42%), Positives = 293/485 (60%), Gaps = 12/485 (2%)
Query: 5 ESASIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAV 64
ES + GLT+DDVL+IP S V R EVN T LS +++L+IP++++ MDTV E MA+
Sbjct: 3 ESKFVKEGLTFDDVLLIPAKSDVLPR-EVNVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 65 AMAREGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXX 124
AMAR+GG+GI+H+ SIE+Q + +VKR++S +I P + P +A E L K
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDA-EHLMGKYRI 120
Query: 125 XXXXXXXXXNCKNERKLLGIITRHDLK-LADESTTVESLMTPVDKMVVSTNTSISLEEVT 183
N +E+KL+GIIT D++ + D S + +MT + +++ +L+E
Sbjct: 121 SGVPIV---NNLDEQKLVGIITNRDMRFIQDYSIKISDVMT--KEQLITAPVGTTLKEAE 175
Query: 184 HLMRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMN 243
+++K + +P+V QNG L L+T+ D+ K+ + ++ D +GRLLVGAAVGV D M
Sbjct: 176 KILQKYKIEKLPLVDQNGVLKGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAML 235
Query: 244 RAIRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXX 303
R LV+A DV+V+D AHGHS + VK ++ + ++
Sbjct: 236 RIDALVKANVDVIVIDTAHGHSQGVLEKVKEVR--TKYPELNIIAGNVATAEATRALIEA 293
Query: 304 XXXXXKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKA 363
K+G+GPGSIC TR+VAG GVPQL+AV C AR+ G+P IADGG++ SGD+ KA
Sbjct: 294 GANIIKVGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKA 353
Query: 364 IGAGADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFS 423
+ AGA VMLG+M AG E+PG + G++ K+ RGM GA + K ++R E
Sbjct: 354 LAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGA-MEKGSKDRYFQEGN-K 411
Query: 424 SLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRES 483
LVPEG+EG V KGP+ V QLVGGLR+GM Y GA +E ++ +F+RMTGAGLRES
Sbjct: 412 KLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAHDLEFLRENAQFIRMTGAGLRES 471
Query: 484 GSHGV 488
H V
Sbjct: 472 HPHHV 476
>gi|6705995|dbj|BAA89464.1| IMPDH [Bacillus cereus]
Length = 509
Score = 349 bits (896), Expect = 2e-94, Method: Composition-based stats.
Identities = 203/485 (41%), Positives = 293/485 (60%), Gaps = 12/485 (2%)
Query: 5 ESASIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAV 64
ES + GLT+DDVL++P S V R EV+ T LS +++L+IP++++ MDTV E MA+
Sbjct: 3 ESKFVKEGLTFDDVLLVPAKSDVLPR-EVSVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 65 AMAREGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXX 124
AMAR+GG+GI+H+ SIE+Q + +VKR++S +I P + P +A E L K
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDA-EHLMGKYRI 120
Query: 125 XXXXXXXXXNCKNERKLLGIITRHDLK-LADESTTVESLMTPVDKMVVSTNTSISLEEVT 183
N +ERKL+GIIT D++ + D S + +MT + +++ +L+E
Sbjct: 121 SGVPVV---NNLDERKLVGIITNRDMRFIQDYSIKISDVMT--KEQLITAPVGTTLDEAE 175
Query: 184 HLMRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMN 243
+++K + +P+V NG L L+T+ D+ K+ + ++ D +GRLLVGAAVGV D M
Sbjct: 176 KILQKYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMT 235
Query: 244 RAIRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXX 303
R LV+A D +V+D AHGHS I+ VK ++ + S++
Sbjct: 236 RIDALVKASVDAIVLDTAHGHSQGVIDKVKEVRA--KYPSLNIIAGNVATAEATGALIEA 293
Query: 304 XXXXXKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKA 363
K+G+GPGSIC TR+VAG GVPQL+AV C AR+ G+P IADGG++ SGD+ KA
Sbjct: 294 GANVVKVGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKA 353
Query: 364 IGAGADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFS 423
+ AGA VMLG+M AG E+PG + G++ K+ RGM GA + K ++R E
Sbjct: 354 LAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGA-MEKGSKDRYFQEGN-K 411
Query: 424 SLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRES 483
LVPEG+EG V KGP+ V QLVGGLR+GM Y GA+ +E ++ +FVRM+GAGL ES
Sbjct: 412 KLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQFVRMSGAGLLES 471
Query: 484 GSHGV 488
H V
Sbjct: 472 HPHHV 476
>gi|6561887|dbj|BAA88235.1| IMP dehydrogenase [Bacillus cereus]
Length = 509
Score = 349 bits (895), Expect = 3e-94, Method: Composition-based stats.
Identities = 202/485 (41%), Positives = 293/485 (60%), Gaps = 12/485 (2%)
Query: 5 ESASIPTGLTYDDVLIIPQHSRVTSRKEVNTTTRLSRNVKLSIPIVASNMDTVCEQRMAV 64
ES + GLT+DDVL++P S + R EV+ T LS +++L+IP++++ MDTV E MA+
Sbjct: 3 ESKFVKEGLTFDDVLLVPARSDILPR-EVSVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 65 AMAREGGIGILHRFCSIEEQCAMLREVKRAQSFLIESPRIILPHETAREAWEGLNWKXXX 124
AMAR+GG+GI+H+ SIE+Q + +VKR++S +I P + P +A E L K
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDA-EHLMGKYRI 120
Query: 125 XXXXXXXXXNCKNERKLLGIITRHDLK-LADESTTVESLMTPVDKMVVSTNTSISLEEVT 183
N +ERKL+GIIT D++ + D S + +MT + +++ +LEE
Sbjct: 121 SGVPVV---NNLDERKLVGIITNRDMRFIQDYSIKISDVMT--KEQLITAPVGTTLEEAE 175
Query: 184 HLMRKGRTANVPIVGQNGQLLYLVTLSDVVKLRKNKQASLDSRGRLLVGAAVGVKKDDMN 243
+++K + +P+V NG L L+T+ D+ K+ + ++ D +GRLLVGAAVGV D
Sbjct: 176 KILQKYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAYL 235
Query: 244 RAIRLVEAGADVLVVDIAHGHSDLCINMVKRLKGDPRTASVDXXXXXXXXXXXXXXXXXX 303
R LV+A D +V+D AHGHS I+ VK ++ + S++
Sbjct: 236 RIDALVKASVDAIVLDTAHGHSKGVIDKVKEVRA--KYPSLNIIAGNVATAEATKALIEA 293
Query: 304 XXXXXKIGVGPGSICITRLVAGAGVPQLSAVLACTRVARRRGVPCIADGGLRTSGDISKA 363
K+G+GPGSIC TR+VAG GVPQL+AV C AR+ G+P IADGG++ SGD+ KA
Sbjct: 294 GENVVKVGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKA 353
Query: 364 IGAGADTVMLGNMLAGTDEAPGRVLVKDGQKVKIIRGMAGFGANLSKAERERTQDEDVFS 423
+ AGA VMLG+M AG E+PG + G++ K+ RGM GA + K ++R E
Sbjct: 354 LAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGA-MEKGSKDRYFQEGN-K 411
Query: 424 SLVPEGVEGSVACKGPVGPIVRQLVGGLRSGMSYSGAKSIEEMQRRTRFVRMTGAGLRES 483
LVPEG+EG V KGP+ V QLVGGLR+GM Y GA+ +E ++ +F+RM+GAGLRES
Sbjct: 412 KLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQFIRMSGAGLRES 471
Query: 484 GSHGV 488
H V
Sbjct: 472 HPHHV 476