BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= CAA33547.1__[Trypanosoma_brucei]
         (607 letters)

Database: nr.pal 
           6,348,806 sequences; 2,166,943,470 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|120744|sp|P13377|G6PI_TRYBB  Glucose-6-phosphate isomeras...  1225   0.0  
gi|160285700|pdb|2O2C|A  Chain A, Crystal Structure Of Phosp...  1219   0.0  
gi|115504569|ref|XP_001219077.1|  glucose-6-phosphate isomer...  1217   0.0  
gi|71667900|ref|XP_820895.1|  glucose-6-phosphate isomerase,...   949   0.0  
gi|71660505|ref|XP_821969.1|  glucose-6-phosphate isomerase,...   946   0.0  
gi|84619567|emb|CAF05827.1|  glucose-6-phosphate isomerase [...   888   0.0  
gi|84619561|emb|CAF05824.1|  glucose-6-phosphate isomerase [...   887   0.0  
gi|146080298|ref|XP_001463984.1|  glucose-6-phosphate isomer...   887   0.0  
gi|84619589|emb|CAF05839.1|  glucose-6-phosphate isomerase [...   885   0.0  
gi|84619575|emb|CAF05831.1|  glucose-6-phosphate isomerase [...   884   0.0  
gi|84619553|emb|CAF05819.1|  glucose-6-phosphate isomerase [...   884   0.0  
gi|157865905|ref|XP_001681659.1|  glucose-6-phosphate isomer...   881   0.0  
gi|1169804|sp|P42861|G6PI_LEIME  Glucose-6-phosphate isomera...   879   0.0  
gi|155675690|gb|ABU25165.1|  glucose-6-phosphate isomerase [...   873   0.0  
gi|155675696|gb|ABU25168.1|  glucose-6-phosphate isomerase [...   873   0.0  
gi|154333685|ref|XP_001563099.1|  glucose-6-phosphate isomer...   873   0.0  
gi|155675692|gb|ABU25166.1|  glucose-6-phosphate isomerase [...   871   0.0  
gi|50513338|pdb|1Q50|A  Chain A, Phosphoglucose Isomerase Fr...   860   0.0  
gi|40737801|gb|AAR89408.1|  glucose-6-phosphate isomerase [T...   855   0.0  
gi|40737805|gb|AAR89410.1|  glucose-6-phosphate isomerase [T...   848   0.0  
gi|40737803|gb|AAR89409.1|  glucose-6-phosphate isomerase [T...   848   0.0  
gi|40737807|gb|AAR89411.1|  glucose-6-phosphate isomerase [T...   847   0.0  
gi|40737809|gb|AAR89412.1|  glucose-6-phosphate isomerase [T...   793   0.0  
gi|40737777|gb|AAR89396.1|  glucose-6-phosphate isomerase [T...   706   0.0  
gi|40737773|gb|AAR89394.1|  glucose-6-phosphate isomerase [T...   705   0.0  
gi|40737781|gb|AAR89398.1|  glucose-6-phosphate isomerase [T...   704   0.0  
gi|40737799|gb|AAR89407.1|  glucose-6-phosphate isomerase [T...   704   0.0  
gi|40737791|gb|AAR89403.1|  glucose-6-phosphate isomerase [T...   703   0.0  
gi|70720762|emb|CAH90643.1|  glucose-6-phosphate isomerase [...   702   0.0  
gi|40737779|gb|AAR89397.1|  glucose-6-phosphate isomerase [T...   701   0.0  
gi|40737797|gb|AAR89406.1|  glucose-6-phosphate isomerase [T...   701   0.0  
gi|40737783|gb|AAR89399.1|  glucose-6-phosphate isomerase [T...   701   0.0  
gi|40737795|gb|AAR89405.1|  glucose-6-phosphate isomerase [T...   699   0.0  
gi|40737789|gb|AAR89402.1|  glucose-6-phosphate isomerase [T...   696   0.0  
gi|40737785|gb|AAR89400.1|  glucose-6-phosphate isomerase [T...   696   0.0  
gi|40737787|gb|AAR89401.1|  glucose-6-phosphate isomerase [T...   696   0.0  
gi|40737793|gb|AAR89404.1|  glucose-6-phosphate isomerase [T...   695   0.0  
gi|70720760|emb|CAH90641.2|  glucose-6-phosphate isomerase [...   690   0.0  
gi|110636894|ref|YP_677101.1|  glucose-6-phosphate isomerase...   676   0.0  
gi|15640401|ref|NP_230028.1|  glucose-6-phosphate isomerase ...   672   0.0  
gi|116215657|ref|ZP_01481622.1|  hypothetical protein VchoR_...   671   0.0  
gi|121729742|ref|ZP_01682182.1|  glucose-6-phosphate isomera...   671   0.0  
gi|94966765|ref|NP_001035561.1|  glucose phosphate isomerase...   671   0.0  
gi|75075955|sp|Q4R591|G6PI_MACFA  Glucose-6-phosphate isomer...   671   0.0  
gi|40737771|gb|AAR89393.1|  glucose-6-phosphate isomerase [T...   670   0.0  
gi|73947978|ref|XP_867960.1|  PREDICTED: similar to Glucose-...   670   0.0  
gi|7245763|pdb|1DQR|A  Chain A, Crystal Structure Of Rabbit ...   670   0.0  
gi|14488628|pdb|1G98|A  Chain A, Crystal Structure Analysis ...   670   0.0  
gi|150423617|gb|EDN15559.1|  glucose-6-phosphate isomerase [...   670   0.0  
gi|126723401|ref|NP_001075538.1|  phosphoglucose isomerase [...   670   0.0  
gi|158936894|dbj|BAF91562.1|  phosphoglucose isomerase [Lepi...   669   0.0  
gi|28948769|pdb|1N8T|A  Chain A, The Crystal Structure Of Ph...   669   0.0  
gi|73947980|ref|XP_867967.1|  PREDICTED: similar to Glucose-...   669   0.0  
gi|20067633|emb|CAC83783.1|  phosphoglucose isomerase [Bufo ...   669   0.0  
gi|21730305|pdb|1GZD|A  Chain A, Crystal Structure Of Pig Ph...   667   0.0  
gi|47523720|ref|NP_999495.1|  glucose phosphate isomerase [S...   667   0.0  
gi|163725681|ref|ZP_02133202.1|  Transketolase [Desulfatibac...   667   0.0  
gi|73947982|ref|XP_853858.1|  PREDICTED: similar to Glucose-...   667   0.0  
gi|46485440|ref|NP_997475.1|  glucose phosphate isomerase [R...   666   0.0  
gi|74202248|dbj|BAE23502.1|  unnamed protein product [Mus mu...   666   0.0  
gi|117620862|ref|YP_854687.1|  glucose-6-phosphate isomerase...   666   0.0  
gi|40737775|gb|AAR89395.1|  glucose-6-phosphate isomerase [T...   666   0.0  
gi|53734472|gb|AAH83507.1|  Glucose phosphate isomerase a [D...   665   0.0  
gi|156554183|ref|XP_001599986.1|  PREDICTED: similar to phos...   665   0.0  
gi|146345422|sp|P06745|G6PI_MOUSE  Glucose-6-phosphate isome...   665   0.0  
gi|82466203|gb|ABB76196.1|  phosphoglucose isomerase [Colias...   664   0.0  
gi|111609767|gb|ABH11436.1|  cytosolic glucose-6-phosphate i...   664   0.0  
gi|158936886|dbj|BAF91557.1|  phosphoglucose isomerase-1 [Os...   664   0.0  
gi|20067651|emb|CAC83779.1|  phosphoglucose isomerase-2 [Mug...   664   0.0  
gi|57524920|ref|NP_001006128.1|  glucose phosphate isomerase...   664   0.0  
gi|145301070|ref|YP_001143911.1|  glucose-6-phosphate isomer...   663   0.0  
gi|6680067|ref|NP_032181.1|  glucose phosphate isomerase 1 [...   663   0.0  
gi|14488680|pdb|1IAT|A  Chain A, Crystal Structure Of Human ...   663   0.0  
gi|18201905|ref|NP_000166.2|  glucose phosphate isomerase [H...   663   0.0  
gi|27881906|gb|AAH44450.1|  Glucose phosphate isomerase a [D...   663   0.0  
gi|30584531|gb|AAP36518.1|  Homo sapiens glucose phosphate i...   663   0.0  
gi|28948422|pdb|1JLH|A  Chain A, Human Glucose-6-Phosphate I...   663   0.0  
gi|66499293|ref|XP_623552.1|  PREDICTED: similar to Glucose-...   663   0.0  
gi|157888726|emb|CAP09263.1|  glucose phosphate isomerase b ...   663   0.0  
gi|77696187|gb|ABB00833.1|  phosphoglucose isomerase [Colias...   662   0.0  
gi|158936884|dbj|BAF91556.1|  phosphoglucose isomerase [Amia...   662   0.0  
gi|82466191|gb|ABB76190.1|  phosphoglucose isomerase [Colias...   662   0.0  
gi|74228751|dbj|BAE21866.1|  unnamed protein product [Mus mu...   662   0.0  
gi|82466195|gb|ABB76192.1|  phosphoglucose isomerase [Colias...   662   0.0  
gi|158936900|dbj|BAF91565.1|  phosphoglucose isomerase-1 [Pl...   662   0.0  
gi|158936888|dbj|BAF91559.1|  phosphoglucose isomerase [Poly...   662   0.0  
gi|74204695|dbj|BAE35416.1|  unnamed protein product [Mus mu...   662   0.0  
gi|74147969|dbj|BAE22329.1|  unnamed protein product [Mus mu...   662   0.0  
gi|82466209|gb|ABB76199.1|  phosphoglucose isomerase [Colias...   662   0.0  
gi|82466193|gb|ABB76191.1|  phosphoglucose isomerase [Colias...   661   0.0  
gi|109157405|pdb|2CVP|A  Chain A, Crystal Structure Of Mouse...   661   0.0  
gi|111609786|gb|ABH11445.1|  cytosolic glucose-6-phosphate i...   661   0.0  
gi|82466189|gb|ABB76189.1|  phosphoglucose isomerase [Colias...   661   0.0  
gi|6653226|gb|AAF22645.1|AF187554_1  sperm antigen-36 [Homo ...   661   0.0  
gi|91085933|ref|XP_970258.1|  PREDICTED: similar to Glucose-...   661   0.0  
gi|113197919|gb|AAI21195.1|  Gpib protein [Danio rerio]           661   0.0  
gi|56554097|pdb|1U0E|A  Chain A, Crystal Structure Of Mouse ...   661   0.0  
gi|82466187|gb|ABB76188.1|  phosphoglucose isomerase [Colias...   660   0.0  
gi|62510579|sp|Q5R4E3|G6PI_PONPY  Glucose-6-phosphate isomer...   660   0.0  
gi|148234425|ref|NP_001085765.1|  MGC80718 protein [Xenopus ...   660   0.0  
>gi|120744|sp|P13377|G6PI_TRYBB Glucose-6-phosphate isomerase, glycosomal (GPI) (Phosphoglucose
           isomerase) (PGI) (Phosphohexose isomerase) (PHI)
 gi|10487|emb|CAA33547.1| unnamed protein product [Trypanosoma brucei]
          Length = 607

 Score = 1225 bits (3169), Expect = 0.0,   Method: Composition-based stats.
 Identities = 591/607 (97%), Positives = 591/607 (97%)

Query: 1   MSSYLDDLRIDLXXXXXXXXXXXXXXXXFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60
           MSSYLDDLRIDL                FNIPYEVTRRLKGVGADADTTLTSCASWTQLQ
Sbjct: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60

Query: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120
           KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA
Sbjct: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120

Query: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180
           EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF
Sbjct: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180

Query: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240
           SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI
Sbjct: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240

Query: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300
           AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS
Sbjct: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300

Query: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360
           TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF
Sbjct: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360

Query: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420
           ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS
Sbjct: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420

Query: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480
           GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF
Sbjct: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480

Query: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540
           FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG
Sbjct: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540

Query: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600
           AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM
Sbjct: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600

Query: 601 FNELSHL 607
           FNELSHL
Sbjct: 601 FNELSHL 607
>gi|160285700|pdb|2O2C|A Chain A, Crystal Structure Of Phosphoglucose Isomerase From T.
           Brucei Containing Glucose-6-Phosphate In The Active Site
 gi|160285701|pdb|2O2C|B Chain B, Crystal Structure Of Phosphoglucose Isomerase From T.
           Brucei Containing Glucose-6-Phosphate In The Active Site
 gi|160285702|pdb|2O2C|C Chain C, Crystal Structure Of Phosphoglucose Isomerase From T.
           Brucei Containing Glucose-6-Phosphate In The Active Site
 gi|160285704|pdb|2O2D|A Chain A, Crystal Structure Of Phosphoglucose Isomerase From
           Trypanosoma Brucei Complexed With Citrate
 gi|160285705|pdb|2O2D|B Chain B, Crystal Structure Of Phosphoglucose Isomerase From
           Trypanosoma Brucei Complexed With Citrate
 gi|160285706|pdb|2O2D|C Chain C, Crystal Structure Of Phosphoglucose Isomerase From
           Trypanosoma Brucei Complexed With Citrate
          Length = 613

 Score = 1219 bits (3154), Expect = 0.0,   Method: Composition-based stats.
 Identities = 588/605 (97%), Positives = 588/605 (97%)

Query: 1   MSSYLDDLRIDLXXXXXXXXXXXXXXXXFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60
           MSSYLDDLRIDL                FNIPYEVTRRLKGVGADADTTLTSCASWTQLQ
Sbjct: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60

Query: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120
           KLYEQYGDEPIKKHFE DSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA
Sbjct: 61  KLYEQYGDEPIKKHFETDSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120

Query: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180
           EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF
Sbjct: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180

Query: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240
           SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI
Sbjct: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240

Query: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300
           AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS
Sbjct: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300

Query: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360
           TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF
Sbjct: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360

Query: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420
           ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS
Sbjct: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420

Query: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480
           GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF
Sbjct: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480

Query: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540
           FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG
Sbjct: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540

Query: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600
           AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM
Sbjct: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600

Query: 601 FNELS 605
           FNELS
Sbjct: 601 FNELS 605
>gi|115504569|ref|XP_001219077.1| glucose-6-phosphate isomerase, glycosomal [Trypanosoma brucei]
 gi|83642559|emb|CAJ16590.1| glucose-6-phosphate isomerase, glycosomal [Trypanosoma brucei]
          Length = 607

 Score = 1217 bits (3149), Expect = 0.0,   Method: Composition-based stats.
 Identities = 587/607 (96%), Positives = 589/607 (97%)

Query: 1   MSSYLDDLRIDLXXXXXXXXXXXXXXXXFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60
           MS+YLDDLR+ L                FNIPYEVTRRLKGVGADADTTLTSCASWTQLQ
Sbjct: 1   MSNYLDDLRMHLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60

Query: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120
           KLYEQYGDEPIKKHFE DSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA
Sbjct: 61  KLYEQYGDEPIKKHFETDSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120

Query: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180
           EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF
Sbjct: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180

Query: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240
           SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI
Sbjct: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240

Query: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300
           AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS
Sbjct: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300

Query: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360
           TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF
Sbjct: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360

Query: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420
           ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS
Sbjct: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420

Query: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480
           GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF
Sbjct: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480

Query: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540
           FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG
Sbjct: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540

Query: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600
           AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM
Sbjct: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600

Query: 601 FNELSHL 607
           FNELSHL
Sbjct: 601 FNELSHL 607
>gi|71667900|ref|XP_820895.1| glucose-6-phosphate isomerase, glycosomal, putative [Trypanosoma
           cruzi strain CL Brener]
 gi|70886257|gb|EAN99044.1| glucose-6-phosphate isomerase, glycosomal, putative [Trypanosoma
           cruzi]
          Length = 608

 Score =  949 bits (2452), Expect = 0.0,   Method: Composition-based stats.
 Identities = 441/604 (73%), Positives = 515/604 (85%)

Query: 4   YLDDLRIDLXXXXXXXXXXXXXXXXFNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLY 63
           YL DL + L                FN+P+E+TRR++ +G D DT+L+SC SW +LQ+LY
Sbjct: 5   YLKDLTVHLNESNAAPANTSMAVASFNMPHEITRRMRPLGVDTDTSLSSCPSWRRLQELY 64

Query: 64  EQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLAEER 123
           E +G E I K+F+   +R QRYS++V L S D+NF+FLDYSK+HINDEIK  L +L EER
Sbjct: 65  EIHGSESILKNFDECKDRFQRYSLEVDLRSSDKNFVFLDYSKTHINDEIKDVLFKLVEER 124

Query: 124 GIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEK 183
           GIR F++++F GE+VNT ENR VLHIALRNRSNRPI+VDG DVMP VNKVL+QM+  SEK
Sbjct: 125 GIRAFMRALFAGEKVNTAENRSVLHIALRNRSNRPIFVDGHDVMPMVNKVLEQMKKISEK 184

Query: 184 VRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEV 243
           VR GEWKG +GK IRHVVNIGIGGSDLGP+MA EALKPFS R +S+HFVSN+DGTH++EV
Sbjct: 185 VRRGEWKGQSGKPIRHVVNIGIGGSDLGPMMACEALKPFSDRRISMHFVSNIDGTHLSEV 244

Query: 244 LKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALSTNN 303
           LK +D+E+TLFI+ASKTFTTQETITNALSAR   L +L SRGI E G+VAKHFVALSTN 
Sbjct: 245 LKLVDLESTLFIIASKTFTTQETITNALSARSEFLKFLSSRGIPEAGAVAKHFVALSTNA 304

Query: 304 QKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHFANA 363
           +KVKEFGIDE NMFQFWDWVGGRYS+WSAIGL +MISIGY+NFVE LTGAH++DEHF NA
Sbjct: 305 EKVKEFGIDEANMFQFWDWVGGRYSLWSAIGLSVMISIGYDNFVEFLTGAHIMDEHFINA 364

Query: 364 PPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKT 423
           P E N+P++LALVG+WY NFFG+ T AILPYDQYLWRLPAYLQQLDMESNGK  T++G+ 
Sbjct: 365 PTENNLPIILALVGIWYNNFFGSETQAILPYDQYLWRLPAYLQQLDMESNGKGATKNGRM 424

Query: 424 VSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQ 483
           VST TGPIIFGEAGTNGQHAFYQLIHQGT LIPCDFIGAIQ+QN IG+HH+I MSNFFAQ
Sbjct: 425 VSTHTGPIIFGEAGTNGQHAFYQLIHQGTKLIPCDFIGAIQTQNYIGEHHRILMSNFFAQ 484

Query: 484 TEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALGAII 543
           TEALMIGK+P EV+RELE+AG +S ++I  L+P KTF GGRPSN+LL+K+LTPRALGAII
Sbjct: 485 TEALMIGKTPEEVKRELESAGGKSEDEIQLLIPQKTFTGGRPSNSLLVKALTPRALGAII 544

Query: 544 AMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNE 603
           AMYEHKVLVQGAIWGI+SYDQWGVELGK+LAKSILPQL+PG +V NHDSSTNGLI +FNE
Sbjct: 545 AMYEHKVLVQGAIWGINSYDQWGVELGKLLAKSILPQLQPGQKVTNHDSSTNGLIKLFNE 604

Query: 604 LSHL 607
            SHL
Sbjct: 605 RSHL 608
>gi|71660505|ref|XP_821969.1| glucose-6-phosphate isomerase, glycosomal, putative [Trypanosoma
           cruzi strain CL Brener]
 gi|26105963|gb|AAN78341.1| TcC31.19 [Trypanosoma cruzi]
 gi|70887360|gb|EAO00118.1| glucose-6-phosphate isomerase, glycosomal, putative [Trypanosoma
           cruzi]
          Length = 608

 Score =  946 bits (2444), Expect = 0.0,   Method: Composition-based stats.
 Identities = 441/604 (73%), Positives = 516/604 (85%)

Query: 4   YLDDLRIDLXXXXXXXXXXXXXXXXFNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLY 63
           YL DL + L                FN+P+E+TRR++ +G DADT+LTSC SW +LQ+LY
Sbjct: 5   YLKDLTVHLNESNAAPANTSMAVASFNMPHEITRRMRPLGVDADTSLTSCPSWRRLQELY 64

Query: 64  EQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLAEER 123
           E +G E I K+F+   +R QRYS++V L S D+NF+FLDYSK+HINDEIK  L +L EER
Sbjct: 65  EIHGSESILKNFDECKDRFQRYSLEVDLRSSDKNFVFLDYSKTHINDEIKDVLFKLVEER 124

Query: 124 GIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEK 183
           GIR F++++F GE+VNT ENR VLHIALRNRSNRPI+V+G DVMP VNKVL+QM+  SEK
Sbjct: 125 GIRAFMRALFAGEKVNTAENRSVLHIALRNRSNRPIFVNGHDVMPLVNKVLEQMKKLSEK 184

Query: 184 VRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEV 243
           VR GEWKG +GK IRHVVNIGIGGSDLGP+MA EAL+PFS R +S+HFVSN+DGTH++EV
Sbjct: 185 VRRGEWKGQSGKPIRHVVNIGIGGSDLGPMMACEALRPFSDRRISMHFVSNIDGTHLSEV 244

Query: 244 LKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALSTNN 303
           L  +D+E+TLFI+ASKTFTTQETITNALSAR   L +L SRGI E G+VAKHFVALSTN 
Sbjct: 245 LNLVDLESTLFIIASKTFTTQETITNALSARNEFLKFLSSRGISEAGAVAKHFVALSTNA 304

Query: 304 QKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHFANA 363
           +KVKEFGIDEENMFQFWDWVGGRYS+WSAIGL +MISIGY+NFVELLTGAH++DEHF NA
Sbjct: 305 EKVKEFGIDEENMFQFWDWVGGRYSLWSAIGLSVMISIGYDNFVELLTGAHIMDEHFINA 364

Query: 364 PPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKT 423
           P E N+P++LALVG+WY NFFG+ T AILPYDQYLWRLPAYLQQLDMESNGK  T++G+ 
Sbjct: 365 PTENNLPIILALVGIWYNNFFGSETQAILPYDQYLWRLPAYLQQLDMESNGKGATKNGRM 424

Query: 424 VSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQ 483
           VST TGPIIFGEAGTNGQHAFYQLIHQGT LIPCDFIGAIQ+QN IG+HH+I MSNFFAQ
Sbjct: 425 VSTHTGPIIFGEAGTNGQHAFYQLIHQGTKLIPCDFIGAIQTQNYIGEHHRILMSNFFAQ 484

Query: 484 TEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALGAII 543
           TEALMIGK+P EV+RELE+AG +S ++I  L+P KTF GGRPSN+LL+K+LTPRALGAII
Sbjct: 485 TEALMIGKTPEEVKRELESAGGKSEDEIQLLIPQKTFTGGRPSNSLLVKALTPRALGAII 544

Query: 544 AMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNE 603
           AMYEHKVLVQGAIWGI+SYDQWGVELGK+LAKSIL QL+PG +V NHDSSTNGLI +FNE
Sbjct: 545 AMYEHKVLVQGAIWGINSYDQWGVELGKLLAKSILLQLQPGQKVTNHDSSTNGLIELFNE 604

Query: 604 LSHL 607
            SHL
Sbjct: 605 RSHL 608
>gi|84619567|emb|CAF05827.1| glucose-6-phosphate isomerase [Leishmania donovani]
          Length = 605

 Score =  888 bits (2295), Expect = 0.0,   Method: Composition-based stats.
 Identities = 423/608 (69%), Positives = 500/608 (82%), Gaps = 4/608 (0%)

Query: 1   MSSYLDDLRID-LXXXXXXXXXXXXXXXXFNIPYEVTRRLKGVGADADTTLTSCASWTQL 59
           MS YL  L+   L                FN PYEV RR K +GA  D++L S  +W +L
Sbjct: 1   MSDYLSKLKXHVLESTEVNGCTPSMATSTFNAPYEVARRTKVLGA-TDSSLLSLPAWKRL 59

Query: 60  QKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRL 119
           Q LYE++G+E I  HFE D +R  RYS++V L S +ENFLFLDYSKSHINDEIK AL+ L
Sbjct: 60  QSLYEKHGNESILSHFENDHQRFGRYSIEVGLHS-EENFLFLDYSKSHINDEIKDALVAL 118

Query: 120 AEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRS 179
           AEERG+R F +++F G+RVN+TENR VLH+ALRNRSNRPI VDGKDVM  VN VL QM+ 
Sbjct: 119 AEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDVMTDVNNVLAQMKD 178

Query: 180 FSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTH 239
           F+EKVR+GEWKG TGK+I ++VNIGIGGSDLGPVM TEALKPFS+RD+   FVSNVDGTH
Sbjct: 179 FTEKVRSGEWKGQTGKSISNIVNIGIGGSDLGPVMVTEALKPFSKRDMHCFFVSNVDGTH 238

Query: 240 IAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVAL 299
           +AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+DYL++  I   G+VAKHFVAL
Sbjct: 239 MAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMDYLKANNISTDGAVAKHFVAL 298

Query: 300 STNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEH 359
           STN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NFVE LTGAHV+D H
Sbjct: 299 STNTEKVREFGIDTVNMFVFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNH 358

Query: 360 FANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTR 419
           FA+AP EQN+P++LALVG+WY NFFGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+
Sbjct: 359 FASAPTEQNLPMMLALVGIWYNNFFGAETEAVLPYDQYLWRLPAYLQQLDMESNGKGVTK 418

Query: 420 SGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSN 479
               V+  TGPIIFGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSN
Sbjct: 419 KSGAVAVQTGPIIFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSN 478

Query: 480 FFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRAL 539
           FFAQTEALM+GKS  EVR+EL  +G  S E I +++PHKTF G RPSN++L+ +LTPRAL
Sbjct: 479 FFAQTEALMVGKSAEEVRQELAKSG-MSDEAIQSMIPHKTFTGNRPSNSILVNALTPRAL 537

Query: 540 GAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLIN 599
           GAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  V++HD STNGLIN
Sbjct: 538 GAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLIN 597

Query: 600 MFNELSHL 607
           MFN  +HL
Sbjct: 598 MFNTRAHL 605
>gi|84619561|emb|CAF05824.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619591|emb|CAF05840.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619593|emb|CAF05841.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619595|emb|CAF05842.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|116486993|emb|CAJ40959.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|116486995|emb|CAJ40960.1| glucose-6-phosphate isomerase [Leishmania donovani]
          Length = 605

 Score =  887 bits (2293), Expect = 0.0,   Method: Composition-based stats.
 Identities = 417/579 (72%), Positives = 493/579 (85%), Gaps = 3/579 (0%)

Query: 29  FNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVK 88
           FN PYEV RR K +GA  D++L S  +W +LQ LYE++G+E I  HFE D +R  RYS++
Sbjct: 30  FNAPYEVARRTKVLGA-TDSSLLSLPAWKRLQSLYEKHGNESILSHFENDHQRFGRYSIE 88

Query: 89  VSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLH 148
           V L S +ENFLFLDYSKSHINDEIK AL+ LAEERG+R F +++F G+RVN+TENR VLH
Sbjct: 89  VGLHS-EENFLFLDYSKSHINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTENRAVLH 147

Query: 149 IALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGS 208
           +ALRNRSNRPI VDGKDVM  VN VL QM+ F+EKVR+GEWKG TGK+I ++VNIGIGGS
Sbjct: 148 VALRNRSNRPIIVDGKDVMTDVNNVLAQMKDFTEKVRSGEWKGQTGKSISNIVNIGIGGS 207

Query: 209 DLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETIT 268
           DLGPVM TEALKPFS+RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+T
Sbjct: 208 DLGPVMVTEALKPFSKRDMHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLT 267

Query: 269 NALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYS 328
           NA+SAR AL+DYL++  I   G+VAKHFVALSTN +KV+EFGID  NMF FWDWVGGRYS
Sbjct: 268 NAMSARNALMDYLKANNISTDGAVAKHFVALSTNTEKVREFGIDTVNMFVFWDWVGGRYS 327

Query: 329 MWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVT 388
           +WSAIGL +M+SIGY+NFVE LTGAHV+D HFA+AP EQN+P++LALVG+WY NFFGA T
Sbjct: 328 VWSAIGLSVMLSIGYDNFVEFLTGAHVMDNHFASAPTEQNLPMMLALVGIWYNNFFGAET 387

Query: 389 HAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLI 448
            A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHAFYQLI
Sbjct: 388 EAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVAVQTGPIIFGEAGTNGQHAFYQLI 447

Query: 449 HQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSA 508
           HQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +G  S 
Sbjct: 448 HQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELAKSG-MSD 506

Query: 509 EKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVE 568
           E I +++PHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVE
Sbjct: 507 EAIQSMIPHKTFTGNRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVE 566

Query: 569 LGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           LGKVLAKSILPQL+ G  V++HD STNGLINMFN  +HL
Sbjct: 567 LGKVLAKSILPQLKSGNIVSDHDGSTNGLINMFNTRAHL 605
>gi|146080298|ref|XP_001463984.1| glucose-6-phosphate isomerase [Leishmania infantum JPCM5]
 gi|78125980|emb|CAF05816.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|78125982|emb|CAF05820.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|78125984|emb|CAF05838.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619549|emb|CAF05817.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|84619551|emb|CAF05818.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|84619555|emb|CAF05821.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619557|emb|CAF05822.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619559|emb|CAF05823.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619563|emb|CAF05825.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|84619565|emb|CAF05826.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619569|emb|CAF05828.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619577|emb|CAF05832.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|84619579|emb|CAF05833.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619581|emb|CAF05834.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619583|emb|CAF05835.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619585|emb|CAF05836.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|84619587|emb|CAF05837.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619597|emb|CAF05843.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619599|emb|CAF05844.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|84619603|emb|CAF05846.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|109450670|emb|CAJ40957.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|109450672|emb|CAJ40958.1| glucose-6-phosphate isomerase [Leishmania donovani]
 gi|109450770|emb|CAJ43255.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|109450772|emb|CAJ43256.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|109450774|emb|CAJ43257.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|109450776|emb|CAJ43258.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|109450778|emb|CAJ43259.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|134068073|emb|CAM66358.1| glucose-6-phosphate isomerase [Leishmania infantum]
          Length = 605

 Score =  887 bits (2292), Expect = 0.0,   Method: Composition-based stats.
 Identities = 417/579 (72%), Positives = 493/579 (85%), Gaps = 3/579 (0%)

Query: 29  FNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVK 88
           FN PYEV RR K +GA  D++L S  +W +LQ LYE++G+E I  HFE D +R  RYS++
Sbjct: 30  FNAPYEVARRTKVLGA-TDSSLLSLPAWKRLQSLYEKHGNESILSHFENDHQRFGRYSIE 88

Query: 89  VSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLH 148
           V L S +ENFLFLDYSKSHINDEIK AL+ LAEERG+R F +++F G+RVN+TENR VLH
Sbjct: 89  VGLHS-EENFLFLDYSKSHINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTENRAVLH 147

Query: 149 IALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGS 208
           +ALRNRSNRPI VDGKDVM  VN VL QM+ F+EKVR+GEWKG TGK+I ++VNIGIGGS
Sbjct: 148 VALRNRSNRPIIVDGKDVMTDVNNVLAQMKDFTEKVRSGEWKGQTGKSISNIVNIGIGGS 207

Query: 209 DLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETIT 268
           DLGPVM TEALKPFS+RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+T
Sbjct: 208 DLGPVMVTEALKPFSKRDMHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLT 267

Query: 269 NALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYS 328
           NA+SAR AL+DYL++  I   G+VAKHFVALSTN +KV+EFGID  NMF FWDWVGGRYS
Sbjct: 268 NAMSARNALMDYLKANNISTDGAVAKHFVALSTNTEKVREFGIDTVNMFVFWDWVGGRYS 327

Query: 329 MWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVT 388
           +WSAIGL +M+SIGY+NFVE LTGAHV+D HFA+AP EQN+P++LALVG+WY NFFGA T
Sbjct: 328 VWSAIGLSVMLSIGYDNFVEFLTGAHVMDNHFASAPTEQNLPMMLALVGIWYNNFFGAET 387

Query: 389 HAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLI 448
            A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHAFYQLI
Sbjct: 388 EAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVAVQTGPIIFGEAGTNGQHAFYQLI 447

Query: 449 HQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSA 508
           HQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +G  S 
Sbjct: 448 HQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELAKSG-MSD 506

Query: 509 EKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVE 568
           E I +++PHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVE
Sbjct: 507 EAIQSMIPHKTFTGNRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVE 566

Query: 569 LGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           LGKVLAKSILPQL+ G  V++HD STNGLINMFN  +HL
Sbjct: 567 LGKVLAKSILPQLKSGNIVSDHDGSTNGLINMFNTRAHL 605
>gi|84619589|emb|CAF05839.1| glucose-6-phosphate isomerase [Leishmania donovani]
          Length = 605

 Score =  885 bits (2288), Expect = 0.0,   Method: Composition-based stats.
 Identities = 416/579 (71%), Positives = 492/579 (84%), Gaps = 3/579 (0%)

Query: 29  FNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVK 88
           FN PYEV RR K +GA  D++L S  +W +LQ LYE++G+E I  HFE D +R  RYS++
Sbjct: 30  FNAPYEVARRTKVLGA-TDSSLLSLPAWKRLQSLYEKHGNESILSHFENDHQRFGRYSIE 88

Query: 89  VSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLH 148
           V L S +ENFLFLDYSKSHINDEIK AL+ LAEERG+R F +++F G+RVN+TENR VLH
Sbjct: 89  VGLHS-EENFLFLDYSKSHINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTENRAVLH 147

Query: 149 IALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGS 208
           +ALRNRSNRPI VDGKDVM  VN VL QM+ F+EKVR+GEWKG TGK+I ++VNIGIGGS
Sbjct: 148 VALRNRSNRPIIVDGKDVMTDVNNVLAQMKDFTEKVRSGEWKGQTGKSISNIVNIGIGGS 207

Query: 209 DLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETIT 268
           DLGPVM TEALKPF +RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+T
Sbjct: 208 DLGPVMVTEALKPFFKRDMHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLT 267

Query: 269 NALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYS 328
           NA+SAR AL+DYL++  I   G+VAKHFVALSTN +KV+EFGID  NMF FWDWVGGRYS
Sbjct: 268 NAMSARNALMDYLKANNISTDGAVAKHFVALSTNTEKVREFGIDTVNMFVFWDWVGGRYS 327

Query: 329 MWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVT 388
           +WSAIGL +M+SIGY+NFVE LTGAHV+D HFA+AP EQN+P++LALVG+WY NFFGA T
Sbjct: 328 VWSAIGLSVMLSIGYDNFVEFLTGAHVMDNHFASAPTEQNLPMMLALVGIWYNNFFGAET 387

Query: 389 HAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLI 448
            A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHAFYQLI
Sbjct: 388 EAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVAVQTGPIIFGEAGTNGQHAFYQLI 447

Query: 449 HQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSA 508
           HQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +G  S 
Sbjct: 448 HQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELAKSG-MSD 506

Query: 509 EKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVE 568
           E I +++PHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVE
Sbjct: 507 EAIQSMIPHKTFTGNRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVE 566

Query: 569 LGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           LGKVLAKSILPQL+ G  V++HD STNGLINMFN  +HL
Sbjct: 567 LGKVLAKSILPQLKSGNIVSDHDGSTNGLINMFNTRAHL 605
>gi|84619575|emb|CAF05831.1| glucose-6-phosphate isomerase [Leishmania infantum]
          Length = 605

 Score =  884 bits (2285), Expect = 0.0,   Method: Composition-based stats.
 Identities = 416/579 (71%), Positives = 492/579 (84%), Gaps = 3/579 (0%)

Query: 29  FNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVK 88
           FN PYEV RR K +GA  D++L S  +W +LQ LYE++G+E I  HFE D +R  RYS++
Sbjct: 30  FNAPYEVARRTKVLGA-TDSSLLSLPAWKRLQSLYEKHGNESILSHFENDHQRFGRYSIE 88

Query: 89  VSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLH 148
           V L S +ENFLFLDYSKSHINDEIK AL+ LAEERG+R F +++F G+RVN+TENR VLH
Sbjct: 89  VGLHS-EENFLFLDYSKSHINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTENRAVLH 147

Query: 149 IALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGS 208
           +ALRNRSNRPI VDGKDVM  VN VL QM+ F+EKVR+GEWKG TGK+I ++VNIGIGGS
Sbjct: 148 VALRNRSNRPIIVDGKDVMTDVNNVLAQMKDFTEKVRSGEWKGQTGKSISNIVNIGIGGS 207

Query: 209 DLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETIT 268
           DLGPVM TEALKPFS+RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+T
Sbjct: 208 DLGPVMVTEALKPFSKRDMHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLT 267

Query: 269 NALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYS 328
           NA+SAR AL+DYL++  I   G+VAKHFVALSTN +KV+EFGID  NMF FWDWVGGRYS
Sbjct: 268 NAMSARNALMDYLKANNISTDGAVAKHFVALSTNTEKVREFGIDTVNMFVFWDWVGGRYS 327

Query: 329 MWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVT 388
           +WSAIGL +M+SIGY+NFVE LTGAHV+D HFA+AP EQN+P++LALVG+WY NFFGA T
Sbjct: 328 VWSAIGLSVMLSIGYDNFVEFLTGAHVMDNHFASAPTEQNLPMMLALVGIWYNNFFGAET 387

Query: 389 HAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLI 448
            A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHAFYQLI
Sbjct: 388 EAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVAVQTGPIIFGEAGTNGQHAFYQLI 447

Query: 449 HQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSA 508
           HQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EV +EL  +G  S 
Sbjct: 448 HQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVXQELAKSG-MSD 506

Query: 509 EKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVE 568
           E I +++PHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVE
Sbjct: 507 EAIQSMIPHKTFTGNRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVE 566

Query: 569 LGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           LGKVLAKSILPQL+ G  V++HD STNGLINMFN  +HL
Sbjct: 567 LGKVLAKSILPQLKSGNIVSDHDGSTNGLINMFNTRAHL 605
>gi|84619553|emb|CAF05819.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|84619571|emb|CAF05829.1| glucose-6-phosphate isomerase [Leishmania infantum]
 gi|84619573|emb|CAF05830.1| glucose-6-phosphate isomerase [Leishmania infantum]
          Length = 605

 Score =  884 bits (2285), Expect = 0.0,   Method: Composition-based stats.
 Identities = 416/579 (71%), Positives = 492/579 (84%), Gaps = 3/579 (0%)

Query: 29  FNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVK 88
           FN PYEV RR K +GA  D++L S  +W +LQ LYE++G+E I  HFE D +R  RYS++
Sbjct: 30  FNAPYEVARRTKVLGA-TDSSLLSLPAWKRLQSLYEKHGNESILSHFENDHQRFGRYSIE 88

Query: 89  VSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLH 148
           V L S +ENFLFLDYSKSHINDEIK AL+ LAEERG+R F +++F G+RVN+TENR VLH
Sbjct: 89  VGLHS-EENFLFLDYSKSHINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTENRAVLH 147

Query: 149 IALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGS 208
           +ALRNRSNRPI VDGKDVM  VN VL QM+ F+EKVR+GEWKG TGK+I ++VNIGIGGS
Sbjct: 148 VALRNRSNRPIIVDGKDVMTDVNNVLAQMKDFTEKVRSGEWKGQTGKSISNIVNIGIGGS 207

Query: 209 DLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETIT 268
           DLGPVM TEALKPFS+RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+T
Sbjct: 208 DLGPVMVTEALKPFSKRDMHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLT 267

Query: 269 NALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYS 328
           NA+SAR AL+DYL++  I   G+VAKHFVALSTN +KV+EFGID  NMF FWDWVGGRYS
Sbjct: 268 NAMSARNALMDYLKANNISTDGAVAKHFVALSTNTEKVREFGIDTVNMFVFWDWVGGRYS 327

Query: 329 MWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVT 388
           +WSAIGL +M+SIGY+NFVE LTGAHV+D HFA+AP EQN+P++LALVG+WY NFFGA T
Sbjct: 328 VWSAIGLSVMLSIGYDNFVEFLTGAHVMDNHFASAPTEQNLPMMLALVGIWYNNFFGAET 387

Query: 389 HAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLI 448
            A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHAFYQLI
Sbjct: 388 EAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVAVQTGPIIFGEAGTNGQHAFYQLI 447

Query: 449 HQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSA 508
           HQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EV +EL  +G  S 
Sbjct: 448 HQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVLQELAKSG-MSD 506

Query: 509 EKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVE 568
           E I +++PHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVE
Sbjct: 507 EAIQSMIPHKTFTGNRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVE 566

Query: 569 LGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           LGKVLAKSILPQL+ G  V++HD STNGLINMFN  +HL
Sbjct: 567 LGKVLAKSILPQLKSGNIVSDHDGSTNGLINMFNTRAHL 605
>gi|157865905|ref|XP_001681659.1| glucose-6-phosphate isomerase [Leishmania major]
 gi|68124957|emb|CAJ02649.1| glucose-6-phosphate isomerase [Leishmania major]
 gi|84619601|emb|CAF05845.1| glucose-6-phosphate isomerase [Leishmania major]
          Length = 605

 Score =  881 bits (2277), Expect = 0.0,   Method: Composition-based stats.
 Identities = 413/579 (71%), Positives = 492/579 (84%), Gaps = 3/579 (0%)

Query: 29  FNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVK 88
           FN PYEV RR K +GA  D++L S  +W +LQ LYE++G+E I  HFE+D +R  RYS++
Sbjct: 30  FNAPYEVARRTKMLGA-TDSSLLSLPAWKRLQSLYEKHGNESILSHFESDHQRFGRYSIE 88

Query: 89  VSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLH 148
           V L S+D NFLFLDYSKSHINDEIK AL+ LAEERG+R F +++F G+RVN+TE+R VLH
Sbjct: 89  VGLHSED-NFLFLDYSKSHINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTEDRAVLH 147

Query: 149 IALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGS 208
           +ALRNRSNRPI VDGKDVM  VN VL QM++F+EKVR+GEWKG TGK+I ++VNIGIGGS
Sbjct: 148 VALRNRSNRPIIVDGKDVMTDVNNVLAQMKNFTEKVRSGEWKGQTGKSISNIVNIGIGGS 207

Query: 209 DLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETIT 268
           DLGPVM TEALKPFS+RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+T
Sbjct: 208 DLGPVMVTEALKPFSKRDMHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLT 267

Query: 269 NALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYS 328
           NA+SAR AL+DYL++  I   G+VAKHFVALSTN +KV+EFGID  NMF FWDWVGGRYS
Sbjct: 268 NAMSARNALMDYLKAHNISTDGAVAKHFVALSTNTEKVREFGIDTVNMFVFWDWVGGRYS 327

Query: 329 MWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVT 388
           +WSAIGL +M+SIGY+NFVE LTGAHV+D HFA+ P EQN+P++LALVG+WY NFFGA T
Sbjct: 328 VWSAIGLSVMLSIGYDNFVEFLTGAHVMDNHFASTPTEQNLPMMLALVGIWYNNFFGAET 387

Query: 389 HAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLI 448
            A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TG IIFGEAGTNGQHAFYQLI
Sbjct: 388 EAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSAAVAVQTGSIIFGEAGTNGQHAFYQLI 447

Query: 449 HQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSA 508
           HQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +G  S 
Sbjct: 448 HQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELVKSG-MSG 506

Query: 509 EKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVE 568
           E +  ++PHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVE
Sbjct: 507 EAMERMIPHKTFTGNRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVE 566

Query: 569 LGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           LGKVLAKSILPQL+ G  V++HD STNGLINMFN  +HL
Sbjct: 567 LGKVLAKSILPQLKSGNIVSDHDGSTNGLINMFNTRAHL 605
>gi|1169804|sp|P42861|G6PI_LEIME Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gi|50513682|pdb|1T10|A Chain A, Phosphoglucose Isomerase From Leishmania Mexicana In
           Complex With Substrate D-Fructose-6-Phosphate
 gi|577070|emb|CAA55042.1| glucose-6-phosphate isomerase [Leishmania mexicana mexicana]
          Length = 605

 Score =  879 bits (2271), Expect = 0.0,   Method: Composition-based stats.
 Identities = 408/579 (70%), Positives = 489/579 (84%), Gaps = 3/579 (0%)

Query: 29  FNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVK 88
           FN PYEV R+ K +G   D++L +  +W +LQ LYE+YG++ I  HFE D +R QRYS++
Sbjct: 30  FNAPYEVARKTKMLGV-TDSSLLNLPAWKRLQSLYEKYGNDSILSHFEKDHQRFQRYSIE 88

Query: 89  VSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLH 148
           + L S D+NFLFLDYSKSHINDEIK AL+ LAEERG+R F +++F G+RVN+TENR VLH
Sbjct: 89  IDLHS-DDNFLFLDYSKSHINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTENRAVLH 147

Query: 149 IALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGS 208
           +ALRNRSNRPI VDGKDVM  VN VL QM+ F+E+VR+GEWKG TGK+I ++VNIGIGGS
Sbjct: 148 VALRNRSNRPIIVDGKDVMSDVNNVLAQMKDFTERVRSGEWKGQTGKSIYNIVNIGIGGS 207

Query: 209 DLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETIT 268
           DLGPVM TEALKPFS+RDL   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+T
Sbjct: 208 DLGPVMVTEALKPFSKRDLHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLT 267

Query: 269 NALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYS 328
           NA+SAR AL+ YL+  GI   G+VAKHFVALSTN +KV+EFGID  NMF FWDWVGGRYS
Sbjct: 268 NAMSARNALMSYLKENGISTDGAVAKHFVALSTNTEKVREFGIDTVNMFAFWDWVGGRYS 327

Query: 329 MWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVT 388
           +WSAIGL +M+SIGY+NFVE LTGAHV+D HFA+ P EQN+P++LALVG+WY NFFG+ T
Sbjct: 328 VWSAIGLSVMLSIGYDNFVEFLTGAHVMDNHFASTPTEQNLPMMLALVGIWYNNFFGSET 387

Query: 389 HAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLI 448
            A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPI+FGEAGTNGQHAFYQLI
Sbjct: 388 QAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVAVQTGPIVFGEAGTNGQHAFYQLI 447

Query: 449 HQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSA 508
           HQGT +IPCDFIG +Q+QN++GDHH+  MSNFFAQTEALM+GK+  EVR+EL  +G  S 
Sbjct: 448 HQGTKIIPCDFIGCVQTQNRVGDHHRTLMSNFFAQTEALMVGKNAEEVRQELVKSG-MSG 506

Query: 509 EKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVE 568
           + I  ++PHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVE
Sbjct: 507 DAIENMIPHKTFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVE 566

Query: 569 LGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           LGKVLAKSILPQL+ G  V++HD STNGLINMFN  +HL
Sbjct: 567 LGKVLAKSILPQLKSGNIVSDHDGSTNGLINMFNTRAHL 605
>gi|155675690|gb|ABU25165.1| glucose-6-phosphate isomerase [Leishmania braziliensis]
          Length = 581

 Score =  873 bits (2256), Expect = 0.0,   Method: Composition-based stats.
 Identities = 405/579 (69%), Positives = 490/579 (84%), Gaps = 3/579 (0%)

Query: 29  FNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVK 88
           FN PYE+ R+ K +GA +D++L+  ++W +L+ LYE+YG E I  HFE D +R  RYS++
Sbjct: 6   FNAPYEIARKTKALGA-SDSSLSKLSAWKRLEFLYEKYGSESILSHFEKDQQRFSRYSIE 64

Query: 89  VSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLH 148
           V L   D+NFLFLDYSKSHINDE+K AL+ LAEERG+R F++++F G++VN+TE R VLH
Sbjct: 65  VPLQC-DDNFLFLDYSKSHINDEVKDALVALAEERGVRAFIKAMFDGQQVNSTEKRAVLH 123

Query: 149 IALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGS 208
           +ALRNRSNR I V+GKD+M  VN VL QM+ F++KVR+GEWKG TGK+I ++VN+GIGGS
Sbjct: 124 VALRNRSNRAINVNGKDIMTDVNLVLAQMKDFTDKVRSGEWKGQTGKSIHYIVNVGIGGS 183

Query: 209 DLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETIT 268
           DLGPVM  E+LKPFS RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+T
Sbjct: 184 DLGPVMVYESLKPFSMRDMHCFFVSNVDGTHMAEVLKQVNMEETIFIIASKTFTTQETLT 243

Query: 269 NALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYS 328
           NA+SAR A +DYL+S  I   G+VAKHFVA+STN ++V+EFGID  NMF+FWDWVGGRYS
Sbjct: 244 NAMSARNAFIDYLKSNNIPSDGAVAKHFVAISTNAKEVREFGIDTANMFEFWDWVGGRYS 303

Query: 329 MWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVT 388
           +WSAIGL +M+SIGYENFVE LTGAHVID HFA+AP EQN+P++LALVG+WY NFFGA T
Sbjct: 304 VWSAIGLSVMLSIGYENFVEFLTGAHVIDNHFASAPVEQNLPMMLALVGIWYNNFFGAET 363

Query: 389 HAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLI 448
            A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHAFYQLI
Sbjct: 364 QAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVTVQTGPIIFGEAGTNGQHAFYQLI 423

Query: 449 HQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSA 508
           HQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +G  S 
Sbjct: 424 HQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELVKSGMPS- 482

Query: 509 EKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVE 568
           + I +LLPHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVE
Sbjct: 483 DAIESLLPHKTFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVE 542

Query: 569 LGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           LGKVLAKSILPQL+ G  V+NHD STNGLINMFN  +HL
Sbjct: 543 LGKVLAKSILPQLKSGNIVSNHDGSTNGLINMFNTRAHL 581
>gi|155675696|gb|ABU25168.1| glucose-6-phosphate isomerase [Leishmania lainsoni]
          Length = 581

 Score =  873 bits (2255), Expect = 0.0,   Method: Composition-based stats.
 Identities = 408/579 (70%), Positives = 487/579 (84%), Gaps = 3/579 (0%)

Query: 29  FNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVK 88
           FN PYE+ R+ K +G  +D++L    +W +LQ LYE+YG E I  HFE D +R  RYS++
Sbjct: 6   FNAPYEIARKTKVLGT-SDSSLLKLPAWKRLQFLYEKYGSESIFSHFEKDQQRFSRYSIE 64

Query: 89  VSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLH 148
           V L   D+NFLFLDYSKSHINDE+K AL+ LAEERG+R F++++F G++VN+TENR VLH
Sbjct: 65  VPL-QGDDNFLFLDYSKSHINDEVKDALVALAEERGVRAFIKAMFDGQQVNSTENRAVLH 123

Query: 149 IALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGS 208
           +ALRNRSNR I V+GKD+M  VN VL QM+ F++KVR+GEWKG TGK+I ++VN+GIGGS
Sbjct: 124 VALRNRSNRVINVNGKDIMADVNLVLAQMKDFTDKVRSGEWKGQTGKSIHYIVNVGIGGS 183

Query: 209 DLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETIT 268
           DLGPVM  EALKPFS RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+T
Sbjct: 184 DLGPVMVYEALKPFSMRDMHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLT 243

Query: 269 NALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYS 328
           NA+SAR AL+DYL+S  I   G+VAKHFVALSTN ++V+EFGID  NMF+FWDWVGGRYS
Sbjct: 244 NAMSARNALMDYLKSNSISSDGAVAKHFVALSTNAKEVREFGIDTANMFEFWDWVGGRYS 303

Query: 329 MWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVT 388
           +WSAIGL +M+SIGYENFVE LTGAHVID HFA+AP EQN+P++LALVG+WY NFFGA T
Sbjct: 304 VWSAIGLSVMLSIGYENFVEFLTGAHVIDNHFASAPVEQNLPMMLALVGIWYNNFFGAET 363

Query: 389 HAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLI 448
            A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHAFYQLI
Sbjct: 364 QAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVTVQTGPIIFGEAGTNGQHAFYQLI 423

Query: 449 HQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSA 508
           HQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +G  S 
Sbjct: 424 HQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELVKSGMPS- 482

Query: 509 EKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVE 568
           + I  LLPHK F G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVE
Sbjct: 483 DAIETLLPHKMFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVE 542

Query: 569 LGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           LGKVLAKSILPQL+ G  V+NHD STNGLINMFN  +HL
Sbjct: 543 LGKVLAKSILPQLKSGNIVSNHDGSTNGLINMFNTRAHL 581
>gi|154333685|ref|XP_001563099.1| glucose-6-phosphate isomerase [Leishmania braziliensis
           MHOM/BR/75/M2904]
 gi|134060109|emb|CAM37422.1| glucose-6-phosphate isomerase [Leishmania braziliensis]
 gi|155675684|gb|ABU25162.1| glucose-6-phosphate isomerase [Leishmania braziliensis]
 gi|155675686|gb|ABU25163.1| glucose-6-phosphate isomerase [Leishmania braziliensis]
 gi|155675688|gb|ABU25164.1| glucose-6-phosphate isomerase [Leishmania peruviana]
          Length = 581

 Score =  873 bits (2255), Expect = 0.0,   Method: Composition-based stats.
 Identities = 405/579 (69%), Positives = 491/579 (84%), Gaps = 3/579 (0%)

Query: 29  FNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVK 88
           FN PYE+ R+ K +GA +D++L+  ++W +L+ LYE+YG+E I  HFE D +R  RYS++
Sbjct: 6   FNAPYEIARKTKVLGA-SDSSLSKLSAWKRLEFLYEKYGNESILSHFEKDQQRFSRYSIE 64

Query: 89  VSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLH 148
           V L   D+NFLFLDYSKSHINDE+K AL+ LAEERG+R F++++F G++VN+TE R VLH
Sbjct: 65  VPLQC-DDNFLFLDYSKSHINDEVKDALVALAEERGVRAFIKAMFDGQQVNSTEKRAVLH 123

Query: 149 IALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGS 208
           +ALRNRSNR I V+GKD+M  VN VL QM+ F++KVR+GEWKG TGK+I ++VN+GIGGS
Sbjct: 124 VALRNRSNRAINVNGKDIMTDVNLVLAQMKDFTDKVRSGEWKGQTGKSIHYIVNVGIGGS 183

Query: 209 DLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETIT 268
           DLGPVM  E+LKPFS RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+T
Sbjct: 184 DLGPVMVYESLKPFSMRDMHCFFVSNVDGTHMAEVLKQVNMEETIFIIASKTFTTQETLT 243

Query: 269 NALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYS 328
           NA+SAR A +DYL+S  I   G+VAKHFVA+STN ++V+EFGID  NMF+FWDWVGGRYS
Sbjct: 244 NAMSARNAFIDYLKSNNIPSDGAVAKHFVAISTNAKEVREFGIDTANMFEFWDWVGGRYS 303

Query: 329 MWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVT 388
           +WSAIGL +M+SIGYENFVE LTGAHVID HFA+AP EQN+P++LALVG+WY NFFGA T
Sbjct: 304 VWSAIGLSVMLSIGYENFVEFLTGAHVIDNHFASAPVEQNLPMMLALVGIWYNNFFGAET 363

Query: 389 HAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLI 448
            A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHAFYQLI
Sbjct: 364 QAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVTVQTGPIIFGEAGTNGQHAFYQLI 423

Query: 449 HQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSA 508
           HQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +G  S 
Sbjct: 424 HQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELVKSGMPS- 482

Query: 509 EKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVE 568
           + I +LLPHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVE
Sbjct: 483 DAIESLLPHKTFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVE 542

Query: 569 LGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           LGKVLAKSILPQL+ G  V+NHD STNGLINMFN  +HL
Sbjct: 543 LGKVLAKSILPQLKSGNIVSNHDGSTNGLINMFNTRAHL 581
>gi|155675692|gb|ABU25166.1| glucose-6-phosphate isomerase [Leishmania guyanensis]
 gi|155675694|gb|ABU25167.1| glucose-6-phosphate isomerase [Leishmania panamensis]
          Length = 581

 Score =  871 bits (2250), Expect = 0.0,   Method: Composition-based stats.
 Identities = 404/579 (69%), Positives = 489/579 (84%), Gaps = 3/579 (0%)

Query: 29  FNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVK 88
           FN PYE+ R+ K +GA +D++L+  ++W +L+ LYE+YG E I  HFE D +R  RYS++
Sbjct: 6   FNAPYEIARKTKVLGA-SDSSLSKLSAWKRLEFLYEKYGSESILSHFEKDQQRFSRYSIE 64

Query: 89  VSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLH 148
           V L   D+NFLFLDYSKSHINDE+K AL+ LAEERG+R F++++F G++VN+TE R VLH
Sbjct: 65  VPLQC-DDNFLFLDYSKSHINDEVKDALVALAEERGVRAFIKAMFDGQQVNSTEKRAVLH 123

Query: 149 IALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGS 208
           +ALRNRSNR I V+GKD+M  VN VL QM+ F+++VR+GEWKG TGK+I ++VN+GIGGS
Sbjct: 124 VALRNRSNRAINVNGKDIMTDVNLVLSQMKDFTDRVRSGEWKGQTGKSIHYIVNVGIGGS 183

Query: 209 DLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETIT 268
           DLGPVM  E+LKPFS RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+T
Sbjct: 184 DLGPVMVYESLKPFSMRDMHCFFVSNVDGTHMAEVLKQVNMEETIFIIASKTFTTQETLT 243

Query: 269 NALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYS 328
           NA+SAR A +DYL+S  I   G+VAKHFVALSTN ++V+EFGID  NMF+FWDWVGGRYS
Sbjct: 244 NAMSARNAFMDYLKSNNIPSDGAVAKHFVALSTNAKEVREFGIDTANMFEFWDWVGGRYS 303

Query: 329 MWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVT 388
           +WSAIGL +M+SIGYENFVE LTGAHVID HF +AP EQN+P++LALVG+WY NFFGA T
Sbjct: 304 VWSAIGLSVMLSIGYENFVEFLTGAHVIDNHFVSAPVEQNLPMMLALVGIWYNNFFGAET 363

Query: 389 HAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLI 448
            A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHAFYQLI
Sbjct: 364 QAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVTVQTGPIIFGEAGTNGQHAFYQLI 423

Query: 449 HQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSA 508
           HQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +G  S 
Sbjct: 424 HQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELVKSGMPS- 482

Query: 509 EKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVE 568
           + I +LLPHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVE
Sbjct: 483 DAIESLLPHKTFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVE 542

Query: 569 LGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           LGKVLAKSILPQL+ G  V+NHD STNGLINMFN  +HL
Sbjct: 543 LGKVLAKSILPQLKSGNIVSNHDGSTNGLINMFNTRAHL 581
>gi|50513338|pdb|1Q50|A Chain A, Phosphoglucose Isomerase From Leishmania Mexicana.
          Length = 561

 Score =  860 bits (2223), Expect = 0.0,   Method: Composition-based stats.
 Identities = 398/560 (71%), Positives = 477/560 (85%), Gaps = 2/560 (0%)

Query: 47  DTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
           D++L +  +W +LQ LYE+YG++ I  HFE D +R QRYS+++ L S D+NFLFLDYSKS
Sbjct: 4   DSSLLNLPAWKRLQSLYEKYGNDSILSHFEKDHQRFQRYSIEIDLHS-DDNFLFLDYSKS 62

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
           HINDEIK AL+ LAEERG+R F +++F G+RVN+TENR VLH+ALRNRSNRPI VDGKDV
Sbjct: 63  HINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDV 122

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           M  VN VL QM+ F+E+VR+GEWKG TGK+I ++VNIGIGGSDLGPVM TEALKPFS+RD
Sbjct: 123 MSDVNNVLAQMKDFTERVRSGEWKGQTGKSIYNIVNIGIGGSDLGPVMVTEALKPFSKRD 182

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
           L   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+ YL+  GI
Sbjct: 183 LHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMSYLKENGI 242

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
              G+VAKHFVALSTN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NF
Sbjct: 243 STDGAVAKHFVALSTNTEKVREFGIDTVNMFAFWDWVGGRYSVWSAIGLSVMLSIGYDNF 302

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
           VE LTGAHV+D HFA+ P EQN+P++LALVG+WY NFFG+ T A+LPYDQYLWRLPAYLQ
Sbjct: 303 VEFLTGAHVMDNHFASTPTEQNLPMMLALVGIWYNNFFGSETQAVLPYDQYLWRLPAYLQ 362

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           QLDMESNGK VT+    V+  TGPI+FGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+Q
Sbjct: 363 QLDMESNGKGVTKKSGAVAVQTGPIVFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQ 422

Query: 467 NKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           N++GDHH+  MSNFFAQTEALM+GK+  EVR+EL  +G  S + I  ++PHKTF G RPS
Sbjct: 423 NRVGDHHRTLMSNFFAQTEALMVGKNAEEVRQELVKSG-MSGDAIENMIPHKTFTGSRPS 481

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  
Sbjct: 482 NSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNI 541

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V++HD STNGLINMFN  +H
Sbjct: 542 VSDHDGSTNGLINMFNTRAH 561
>gi|40737801|gb|AAR89408.1| glucose-6-phosphate isomerase [Trypanosoma brucei gambiense]
          Length = 411

 Score =  855 bits (2210), Expect = 0.0,   Method: Composition-based stats.
 Identities = 410/411 (99%), Positives = 410/411 (99%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP
Sbjct: 1   NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS
Sbjct: 61  VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA
Sbjct: 121 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL
Sbjct: 181 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
           NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN
Sbjct: 301 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           ALLPHK FIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD
Sbjct: 361 ALLPHKXFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 411
>gi|40737805|gb|AAR89410.1| glucose-6-phosphate isomerase [Trypanosoma brucei brucei]
          Length = 411

 Score =  848 bits (2191), Expect = 0.0,   Method: Composition-based stats.
 Identities = 407/411 (99%), Positives = 407/411 (99%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTG A  HVVNIGIGGSDLGP
Sbjct: 1   NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGNAXXHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS
Sbjct: 61  VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA
Sbjct: 121 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL
Sbjct: 181 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
           NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN
Sbjct: 301 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           ALLPHK FIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD
Sbjct: 361 ALLPHKXFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 411
>gi|40737803|gb|AAR89409.1| glucose-6-phosphate isomerase [Trypanosoma brucei gambiense]
          Length = 406

 Score =  848 bits (2190), Expect = 0.0,   Method: Composition-based stats.
 Identities = 406/406 (100%), Positives = 406/406 (100%)

Query: 157 RPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMAT 216
           RPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMAT
Sbjct: 1   RPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMAT 60

Query: 217 EALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRA 276
           EALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRA
Sbjct: 61  EALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRA 120

Query: 277 LLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLP 336
           LLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLP
Sbjct: 121 LLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLP 180

Query: 337 IMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQ 396
           IMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQ
Sbjct: 181 IMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQ 240

Query: 397 YLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIP 456
           YLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIP
Sbjct: 241 YLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIP 300

Query: 457 CDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLP 516
           CDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLP
Sbjct: 301 CDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLP 360

Query: 517 HKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSY 562
           HKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSY
Sbjct: 361 HKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSY 406
>gi|40737807|gb|AAR89411.1| glucose-6-phosphate isomerase [Trypanosoma brucei rhodesiense]
          Length = 412

 Score =  847 bits (2188), Expect = 0.0,   Method: Composition-based stats.
 Identities = 407/412 (98%), Positives = 407/412 (98%)

Query: 152 RNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLG 211
           RNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKV T EWKGHTGKA  HVVNIGIGGSDLG
Sbjct: 1   RNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVXTXEWKGHTGKAXXHVVNIGIGGSDLG 60

Query: 212 PVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNAL 271
           PVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNAL
Sbjct: 61  PVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNAL 120

Query: 272 SARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWS 331
           SARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWS
Sbjct: 121 SARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWS 180

Query: 332 AIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAI 391
           AIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAI
Sbjct: 181 AIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAI 240

Query: 392 LPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQG 451
           LPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQG
Sbjct: 241 LPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQG 300

Query: 452 TNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKI 511
           TNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKI
Sbjct: 301 TNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKI 360

Query: 512 NALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           NALLPHK FIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD
Sbjct: 361 NALLPHKXFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 412
>gi|40737809|gb|AAR89412.1| glucose-6-phosphate isomerase [Trypanosoma congolense]
          Length = 411

 Score =  793 bits (2049), Expect = 0.0,   Method: Composition-based stats.
 Identities = 373/411 (90%), Positives = 395/411 (96%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPI VDGKDVMP VNKVLDQM  FS+KVR GEWKGHTGK+IRHVVNIGIGGSDLGP
Sbjct: 1   NRSNRPILVDGKDVMPDVNKVLDQMHCFSDKVRNGEWKGHTGKSIRHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           VMATEALKPFSQR +SLHFVSNVDGTHI+EVLKSIDIEATLFIVASKTFTTQETITNALS
Sbjct: 61  VMATEALKPFSQRSISLHFVSNVDGTHISEVLKSIDIEATLFIVASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           AR ALL+YL+S+GI++ G+VA HFVALSTN +KVKEFGIDEENMFQFWDWVGGRYS+WSA
Sbjct: 121 ARNALLNYLKSQGINDDGAVAXHFVALSTNTRKVKEFGIDEENMFQFWDWVGGRYSLWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGLPIMISIGYENFVELLTGA V+DEHF N PPE+N+P+LLALVGVWYINFFGAVTHAIL
Sbjct: 181 IGLPIMISIGYENFVELLTGAFVVDEHFVNEPPERNIPMLLALVGVWYINFFGAVTHAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGK VTR+G+TVSTLTGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKCVTRNGETVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
           NLIPCDFIGAIQ+QNKIGDHHKIFMSNFFAQTEALMIGK+P EVRRELEAAGE+SA+KI 
Sbjct: 301 NLIPCDFIGAIQTQNKIGDHHKIFMSNFFAQTEALMIGKTPIEVRRELEAAGEKSADKIK 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD
Sbjct: 361 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 411
>gi|40737777|gb|AAR89396.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 411

 Score =  706 bits (1823), Expect = 0.0,   Method: Composition-based stats.
 Identities = 325/411 (79%), Positives = 369/411 (89%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPI+VDG DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP
Sbjct: 1   NRSNRPIFVDGNDVMPLVNKVLEQMKKLSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           +MA EALKPFS R +S+HFVSN+DGTH++EVLK +D+E+TLFI+ASKTFTTQETITNALS
Sbjct: 61  MMACEALKPFSDRKISMHFVSNIDGTHLSEVLKLVDLESTLFIIASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           AR   L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSA
Sbjct: 121 ARSEFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEANMFQFWDWVGGRYSLWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGL +MISIGY+NFVE LTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AIL
Sbjct: 181 IGLSVMISIGYDNFVEFLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
            LIPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I 
Sbjct: 301 KLIPCDFIGAIQTQNHIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQ 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
            L+P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 361 LLIPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYD 411
>gi|40737773|gb|AAR89394.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 411

 Score =  705 bits (1819), Expect = 0.0,   Method: Composition-based stats.
 Identities = 324/411 (78%), Positives = 369/411 (89%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPI+V+G DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP
Sbjct: 1   NRSNRPIFVNGNDVMPLVNKVLEQMKKLSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           +MA EALKPFS R +S+HFVSN+DGTH++EVLK +D+E+TLFI+ASKTFTTQETITNALS
Sbjct: 61  MMACEALKPFSDRRISMHFVSNIDGTHLSEVLKLVDLESTLFIIASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           AR   L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSA
Sbjct: 121 ARSEFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEANMFQFWDWVGGRYSLWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGL +MISIGY+NFVE LTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AIL
Sbjct: 181 IGLSVMISIGYDNFVEFLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
            LIPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I 
Sbjct: 301 KLIPCDFIGAIQTQNCIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQ 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
            L+P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 361 LLIPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYD 411