BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= CAA46577.1__[Trypanosoma_brucei]
         (479 letters)

Database: nr.pal 
           6,348,806 sequences; 2,166,943,470 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|398975|sp|P31072|6PGD_TRYBB  6-phosphogluconate dehydroge...   934   0.0  
gi|71745666|ref|XP_827463.1|  6-phosphogluconate dehydrogena...   931   0.0  
gi|3891386|pdb|1PGJ|A  Chain A, X-Ray Structure Of 6-Phospho...   929   0.0  
gi|34329200|gb|AAQ63817.1|  6-phosphogluconate dehydrogenase...   760   0.0  
gi|71411576|ref|XP_808031.1|  6-phosphogluconate dehydrogena...   759   0.0  
gi|109450756|emb|CAJ43106.1|  phosphogluconate dehydrogenase...   691   0.0  
gi|157741853|gb|ABV69581.1|  6-phosphogluconate dehydrogenas...   688   0.0  
gi|72548846|ref|XP_843439.1|  6-phosphogluconate dehydrogena...   686   0.0  
gi|165882000|gb|ABY71266.1|  6-phosphogluconate dehydrogenas...   685   0.0  
gi|109450754|emb|CAJ43105.1|  phosphogluconate dehydrogenase...   683   0.0  
gi|14719818|gb|AAF64171.2|  6-phosphogluconate dehydrogenase...   683   0.0  
gi|15625244|gb|AAL01643.1|  6-phosphogluconate dehydrogenase...   682   0.0  
gi|157741847|gb|ABV69578.1|  6-phosphogluconate dehydrogenas...   682   0.0  
gi|154344979|ref|XP_001568431.1|  6-phosphogluconate dehydro...   681   0.0  
gi|163963119|gb|ABY50511.1|  6-phosphogluconate dehydrogenas...   680   0.0  
gi|157741851|gb|ABV69580.1|  6-phosphogluconate dehydrogenas...   678   0.0  
gi|157741849|gb|ABV69579.1|  6-phosphogluconate dehydrogenas...   674   0.0  
gi|109450738|emb|CAJ43098.1|  phosphogluconate dehydrogenase...   674   0.0  
gi|146101549|ref|XP_001469143.1|  6-phosphogluconate dehydro...   674   0.0  
gi|109450702|emb|CAJ43081.1|  phosphogluconate dehydrogenase...   674   0.0  
gi|37528837|gb|AAQ92344.1|  6-phosphogluconate dehydrogenase...   673   0.0  
gi|109450730|emb|CAJ43094.1|  phosphogluconate dehydrogenase...   673   0.0  
gi|109450718|emb|CAJ43088.1|  phosphogluconate dehydrogenase...   673   0.0  
gi|109450706|emb|CAJ43082.1|  phosphogluconate dehydrogenase...   673   0.0  
gi|109450806|emb|CAJ43273.1|  phosphogluconate dehydrogenase...   642   0.0  
gi|71413106|ref|XP_808707.1|  6-phosphogluconate dehydrogena...   457   e-127
gi|37727179|gb|AAO38989.1|  6-phosphogluconate dehydrogenase...   436   e-120
gi|37726610|gb|AAO38995.1|  6-phosphogluconate dehydrogenase...   425   e-117
gi|37726606|gb|AAO38993.1|  6-phosphogluconate dehydrogenase...   424   e-117
gi|28883207|gb|AAO50081.1|  6-phosphogluconate dehydrogenase...   424   e-117
gi|37726600|gb|AAO38990.1|  6-phosphogluconate dehydrogenase...   422   e-116
gi|37725961|gb|AAO38983.1|  6-phosphogluconate dehydrogenase...   421   e-116
gi|37725963|gb|AAO38984.1|  6-phosphogluconate dehydrogenase...   420   e-115
gi|37725965|gb|AAO38985.1|  6-phosphogluconate dehydrogenase...   419   e-115
gi|37725971|gb|AAO38988.1|  6-phosphogluconate dehydrogenase...   416   e-114
gi|37726608|gb|AAO38994.1|  6-phosphogluconate dehydrogenase...   416   e-114
gi|37725969|gb|AAO38987.1|  6-phosphogluconate dehydrogenase...   415   e-114
gi|62241815|emb|CAI61960.1|  6-phosphogluconate dehydrogenas...   414   e-114
gi|37725959|gb|AAO38982.1|  6-phosphogluconate dehydrogenase...   414   e-114
gi|37725957|gb|AAO38981.1|  6-phosphogluconate dehydrogenase...   412   e-113
gi|62241817|emb|CAI61961.1|  6-phosphogluconate dehydrogenas...   412   e-113
gi|62241813|emb|CAI61959.1|  6-phosphogluconate dehydrogenas...   412   e-113
gi|62241803|emb|CAI61954.1|  6-phosphogluconate dehydrogenas...   410   e-113
gi|62241819|emb|CAI61962.1|  6-phosphogluconate dehydrogenas...   410   e-112
gi|28883205|gb|AAO50080.1|  6-phosphogluconate dehydrogenase...   409   e-112
gi|91070288|gb|ABE11206.1|  6-phosphogluconate dehydrogenase...   318   6e-85
gi|78779162|ref|YP_397274.1|  6-phosphogluconate dehydrogena...   318   7e-85
gi|157413199|ref|YP_001484065.1|  6-phosphogluconate dehydro...   317   9e-85
gi|126696168|ref|YP_001091054.1|  6-phosphogluconate dehydro...   317   1e-84
gi|126656205|ref|ZP_01727589.1|  6-phosphogluconate dehydrog...   315   6e-84
gi|123968365|ref|YP_001009223.1|  6-phosphogluconate dehydro...   311   5e-83
gi|67922824|ref|ZP_00516323.1|  6-phosphogluconate dehydroge...   311   8e-83
gi|119492098|ref|ZP_01623551.1|  6-phosphogluconate dehydrog...   306   2e-81
gi|33861327|ref|NP_892888.1|  6-phosphogluconate dehydrogena...   306   2e-81
gi|123966048|ref|YP_001011129.1|  6-phosphogluconate dehydro...   305   6e-81
gi|159028626|emb|CAO90629.1|  gnd [Microcystis aeruginosa PC...   305   7e-81
gi|159899144|ref|YP_001545391.1|  6-phosphogluconate dehydro...   305   7e-81
gi|124522009|ref|ZP_01696777.1|  6-phosphogluconate dehydrog...   303   2e-80
gi|119512001|ref|ZP_01631097.1|  6-phosphogluconate dehydrog...   302   3e-80
gi|87302824|ref|ZP_01085635.1|  6-phosphogluconate dehydroge...   301   7e-80
gi|15672604|ref|NP_266778.1|  6-phosphogluconate dehydrogena...   300   1e-79
gi|17232767|ref|NP_489315.1|  6-phosphogluconate dehydrogena...   300   2e-79
gi|75908741|ref|YP_323037.1|  6-phosphogluconate dehydrogena...   299   4e-79
gi|116511415|ref|YP_808631.1|  6-phosphogluconate dehydrogen...   298   5e-79
gi|81298850|ref|YP_399058.1|  6-phosphogluconate dehydrogena...   298   6e-79
gi|147499|gb|AAA24494.1|  6-phosphogluconate dehydrogenase        297   1e-78
gi|11464516|gb|AAG35218.1|  6-phosphogluconate dehydrogenase...   297   1e-78
gi|56123318|gb|AAV74553.1|  Gnd [Escherichia coli]                297   1e-78
gi|78184799|ref|YP_377234.1|  6-phosphogluconate dehydrogena...   297   1e-78
gi|116070672|ref|ZP_01467941.1|  6-phosphogluconate dehydrog...   297   1e-78
gi|83588030|ref|ZP_00926655.1|  COG0362: 6-phosphogluconate ...   297   1e-78
gi|147493|gb|AAA24491.1|  6-phosphogluconate dehydrogenase >...   297   2e-78
gi|146232|gb|AAA23918.1|  6-phosphogluconate dehydrogenase (...   297   2e-78
gi|90961622|ref|YP_535538.1|  6-phosphogluconate dehydrogena...   296   2e-78
gi|161502753|ref|YP_001569865.1|  hypothetical protein SARI_...   296   2e-78
gi|75177157|ref|ZP_00697255.1|  COG0362: 6-phosphogluconate ...   296   2e-78
gi|11464518|gb|AAG35219.1|  6-phosphogluconate dehydrogenase...   296   2e-78
gi|162418185|ref|YP_001607536.1|  6-phosphogluconate dehydro...   296   2e-78
gi|29375628|ref|NP_814782.1|  6-phosphogluconate dehydrogena...   296   2e-78
gi|22126509|ref|NP_669932.1|  6-phosphogluconate dehydrogena...   296   2e-78
gi|45441255|ref|NP_992794.1|  6-phosphogluconate dehydrogena...   296   2e-78
gi|16121814|ref|NP_405127.1|  6-phosphogluconate dehydrogena...   296   2e-78
gi|37520686|ref|NP_924063.1|  6-phosphogluconate dehydrogena...   296   2e-78
gi|72382016|ref|YP_291371.1|  6-phosphogluconate dehydrogena...   296   2e-78
gi|170769726|ref|ZP_02904179.1|  6-phosphogluconate dehydrog...   296   2e-78
gi|126030879|pdb|2IZ0|A  Chain A, Pex Inhibitor-Home Data >g...   296   2e-78
gi|16129970|ref|NP_416533.1|  gluconate-6-phosphate dehydrog...   296   2e-78
gi|170076852|ref|YP_001733490.1|  6-phosphogluconate dehydro...   296   2e-78
gi|170019644|ref|YP_001724598.1|  6-phosphogluconate dehydro...   296   2e-78
gi|15802508|ref|NP_288534.1|  6-phosphogluconate dehydrogena...   296   2e-78
gi|4867927|dbj|BAA77736.1|  6-phosphogluconate dehydrogenase...   296   2e-78
gi|77959279|ref|ZP_00823300.1|  COG0362: 6-phosphogluconate ...   296   3e-78
gi|123442989|ref|YP_001006964.1|  6-phosphogluconate dehydro...   296   3e-78
gi|126030876|pdb|2IYP|A  Chain A, Product Rup >gi|126030877|...   296   3e-78
gi|126030875|pdb|2IYO|A  Chain A, Structural Characterizatio...   296   3e-78
gi|158335248|ref|YP_001516420.1|  6-phosphogluconate dehydro...   296   3e-78
gi|75514070|ref|ZP_00736400.1|  COG0362: 6-phosphogluconate ...   295   4e-78
gi|147491|gb|AAA24490.1|  6-phosphogluconate dehydrogenase        295   4e-78
gi|23130041|ref|ZP_00111860.1|  COG0362: 6-phosphogluconate ...   295   4e-78
gi|125623448|ref|YP_001031931.1|  6-phosphogluconate dehydro...   295   4e-78
>gi|398975|sp|P31072|6PGD_TRYBB 6-phosphogluconate dehydrogenase, decarboxylating
 gi|10409|emb|CAA46577.1| 6-phosphogluconate dehydrogenase (decarboxylating) [Trypanosoma
           brucei]
          Length = 479

 Score =  934 bits (2413), Expect = 0.0,   Method: Composition-based stats.
 Identities = 463/479 (96%), Positives = 463/479 (96%)

Query: 1   MSMDXXXXXXXXXXXXXXXXIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETM 60
           MSMD                IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETM
Sbjct: 1   MSMDVGVVGLGVMGANLALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETM 60

Query: 61  EAFAASLKKPRKALILVQAGAATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEA 120
           EAFAASLKKPRKALILVQAGAATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEA
Sbjct: 61  EAFAASLKKPRKALILVQAGAATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEA 120

Query: 121 AGLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGG 180
           AGLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGG
Sbjct: 121 AGLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGG 180

Query: 181 AGSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIA 240
           AGSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIA
Sbjct: 181 AGSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIA 240

Query: 241 AARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQ 300
           AARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQ
Sbjct: 241 AARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQ 300

Query: 301 ANASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGL 360
           ANASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGL
Sbjct: 301 ANASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGL 360

Query: 361 NLPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITS 420
           NLPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITS
Sbjct: 361 NLPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITS 420

Query: 421 KLEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           KLEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ
Sbjct: 421 KLEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
>gi|71745666|ref|XP_827463.1| 6-phosphogluconate dehydrogenase decarboxylating [Trypanosoma
           brucei]
 gi|70831628|gb|EAN77133.1| 6-phosphogluconate dehydrogenase, decarboxylating, putative
           [Trypanosoma brucei]
          Length = 479

 Score =  931 bits (2407), Expect = 0.0,   Method: Composition-based stats.
 Identities = 462/479 (96%), Positives = 462/479 (96%)

Query: 1   MSMDXXXXXXXXXXXXXXXXIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETM 60
           MSMD                IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETM
Sbjct: 1   MSMDVGVVGLGVMGANLALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETM 60

Query: 61  EAFAASLKKPRKALILVQAGAATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEA 120
           EAFAASLKKPRKALILVQAGAATDST EQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEA
Sbjct: 61  EAFAASLKKPRKALILVQAGAATDSTIEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEA 120

Query: 121 AGLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGG 180
           AGLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGG
Sbjct: 121 AGLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGG 180

Query: 181 AGSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIA 240
           AGSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIA
Sbjct: 181 AGSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIA 240

Query: 241 AARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQ 300
           AARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQ
Sbjct: 241 AARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQ 300

Query: 301 ANASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGL 360
           ANASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGL
Sbjct: 301 ANASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGL 360

Query: 361 NLPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITS 420
           NLPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITS
Sbjct: 361 NLPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITS 420

Query: 421 KLEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           KLEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ
Sbjct: 421 KLEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
>gi|3891386|pdb|1PGJ|A Chain A, X-Ray Structure Of 6-Phosphogluconate Dehydrogenase From
           The Protozoan Parasite T. Brucei
 gi|3891387|pdb|1PGJ|B Chain B, X-Ray Structure Of 6-Phosphogluconate Dehydrogenase From
           The Protozoan Parasite T. Brucei
          Length = 478

 Score =  929 bits (2402), Expect = 0.0,   Method: Composition-based stats.
 Identities = 461/478 (96%), Positives = 461/478 (96%)

Query: 2   SMDXXXXXXXXXXXXXXXXIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETME 61
           SMD                IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETME
Sbjct: 1   SMDVGVVGLGVMGANLALNIAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETME 60

Query: 62  AFAASLKKPRKALILVQAGAATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAA 121
           AFAASLKKPRKALILVQAGAATDST EQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAA
Sbjct: 61  AFAASLKKPRKALILVQAGAATDSTIEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAA 120

Query: 122 GLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGA 181
           GLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGA
Sbjct: 121 GLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGA 180

Query: 182 GSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAA 241
           GSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAA
Sbjct: 181 GSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAA 240

Query: 242 ARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQA 301
           ARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQA
Sbjct: 241 ARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQA 300

Query: 302 NASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLN 361
           NASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLN
Sbjct: 301 NASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLN 360

Query: 362 LPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSK 421
           LPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSK
Sbjct: 361 LPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSK 420

Query: 422 LEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           LEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ
Sbjct: 421 LEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 478
>gi|34329200|gb|AAQ63817.1| 6-phosphogluconate dehydrogenase [Trypanosoma cruzi]
          Length = 477

 Score =  760 bits (1963), Expect = 0.0,   Method: Composition-based stats.
 Identities = 360/459 (78%), Positives = 409/459 (89%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGF VAVFNRTYSK+E F+K +ASAPFA NLKA+ETM +F  ++KKPRK  ILVQAG
Sbjct: 19  IAEKGFHVAVFNRTYSKAESFIKEHASAPFAANLKAYETMNSFIMAIKKPRKIFILVQAG 78

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATD+T EQLK V EK DI+VDTGNAHFKDQ RRA+QLEAAGLRFLGMGISGGEEGARKG
Sbjct: 79  AATDATIEQLKGVLEKDDIIVDTGNAHFKDQTRRAEQLEAAGLRFLGMGISGGEEGARKG 138

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGTLSVW+EI+P+VEAAAAKADDGRPCVTMNG GGAGSCVKMYHN+GEYA+LQ+W
Sbjct: 139 PAFFPGGTLSVWKEIQPVVEAAAAKADDGRPCVTMNGRGGAGSCVKMYHNAGEYAVLQVW 198

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE FDILRAMGL+NDEVAAV EDWK+K FL SYMLDISI AARAK  DGS+L+EHV D I
Sbjct: 199 GEAFDILRAMGLSNDEVAAVFEDWKAKGFLTSYMLDISIVAARAKVADGSHLSEHVKDCI 258

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSLNMAV+SRQ TMYK+ER+ NA   P + + PGY +K+K
Sbjct: 259 GSKGTGLWSAQEALEVGVPAPSLNMAVLSRQMTMYKSERELNAKTLPFVLKVPGYAIKDK 318

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PEI+QLY +V IAII+CYAQMFQCLR +DKV++FGL+LPATIATFRAGCIL+GYLL
Sbjct: 319 SPNAPEIRQLYHAVSIAIIACYAQMFQCLRALDKVYDFGLDLPATIATFRAGCILKGYLL 378

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
           +PMTEAF KN N+SNLMCAF+ EI  GLQ+YRD++  ITSK  +++PVLSASL YV  MF
Sbjct: 379 QPMTEAFAKNVNLSNLMCAFEKEITEGLQSYRDILGFITSKTALTLPVLSASLVYVNGMF 438

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           TPTL+YGQLVSLQRDVFGRHGYER+DK+GRES QWPELQ
Sbjct: 439 TPTLRYGQLVSLQRDVFGRHGYERLDKEGRESHQWPELQ 477
>gi|71411576|ref|XP_808031.1| 6-phosphogluconate dehydrogenase, decarboxylating, putative
           [Trypanosoma cruzi strain CL Brener]
 gi|34329198|gb|AAQ63816.1| 6-phosphogluconate dehydrogenase [Trypanosoma cruzi]
 gi|70872152|gb|EAN86180.1| 6-phosphogluconate dehydrogenase, decarboxylating, putative
           [Trypanosoma cruzi]
          Length = 477

 Score =  759 bits (1959), Expect = 0.0,   Method: Composition-based stats.
 Identities = 358/459 (77%), Positives = 410/459 (89%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGF VAVFNRTYSK+E F+K +ASAPFA NLKA+ETM++F  ++KKPRK  ILVQAG
Sbjct: 19  IAEKGFHVAVFNRTYSKAESFIKEHASAPFAANLKAYETMKSFIMAIKKPRKIFILVQAG 78

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATD+T EQLK V EK DI+VDTGNAHFKDQ RRA+QLEAAGLRFLGMGISGGEEGARKG
Sbjct: 79  AATDATIEQLKGVLEKDDIIVDTGNAHFKDQTRRAEQLEAAGLRFLGMGISGGEEGARKG 138

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGTLSVW+EI+P+VEAAAAKADDGRPCVTMNG GGAGSCVKMYHN+GEYA+LQ+W
Sbjct: 139 PAFFPGGTLSVWKEIQPVVEAAAAKADDGRPCVTMNGRGGAGSCVKMYHNAGEYAVLQVW 198

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE FD+LRAMGL+NDEVAAV EDWK+K FL SYMLDISI AARAK  DGS+L+EHV D I
Sbjct: 199 GEAFDVLRAMGLSNDEVAAVFEDWKAKGFLTSYMLDISIVAARAKVADGSHLSEHVKDCI 258

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSLNMAV+SRQ TMYK+ER+ NA   P + + PGY +K+K
Sbjct: 259 GSKGTGLWSAQEALEVGVPAPSLNMAVLSRQMTMYKSERELNAKTLPFVLKVPGYAIKDK 318

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PEI+QLY +V IAII+CYAQMFQCLR +DKV++FGL+LPATIATFRAGCIL+GYLL
Sbjct: 319 SPNAPEIRQLYHAVSIAIIACYAQMFQCLRALDKVYDFGLDLPATIATFRAGCILKGYLL 378

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
           +PMTEAF KN  +SNL+CAF+ EIR GLQ+YRD++  ITSK  +++PVLSASL YV  MF
Sbjct: 379 QPMTEAFAKNVKLSNLLCAFEKEIREGLQSYRDILGFITSKTALTLPVLSASLVYVNGMF 438

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           TPTL+YGQLVSLQRDVFGRHGYER+DK+GRES QWPELQ
Sbjct: 439 TPTLRYGQLVSLQRDVFGRHGYERLDKEGRESHQWPELQ 477
>gi|109450756|emb|CAJ43106.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           killicki]
          Length = 479

 Score =  691 bits (1782), Expect = 0.0,   Method: Composition-based stats.
 Identities = 332/459 (72%), Positives = 382/459 (83%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRTY+K+  F+K + S  FA NL  +ETM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTYTKTTSFLKEHESEKFAANLNGYETMKGFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+VFE GDI++DTGNA+FKDQ +RA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVFENGDIIIDTGNANFKDQDKRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  LRA G +ND++A V + WK+  FLKSYMLDISIAA RA++  G+YL+E V DRI
Sbjct: 201 GEAYSALRAFGFDNDQIADVFDSWKADGFLKSYMLDISIAACRAREAAGNYLSEKVKDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSLNMAV+SRQ TMYK ER AN    P   + P     +K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLNMAVISRQMTMYKEERIANCKAFPNFPRGPSEEATDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE KQLY +V + II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPEAKQLYHAVSLCIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NPN+ NLM AF  EI AGL N R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPNLPNLMDAFTKEIAAGLHNCRQILAKLTVNTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T TL YGQLVSLQRDVFGRHGYER D+DGRESF+WP LQ
Sbjct: 441 TETLPYGQLVSLQRDVFGRHGYERTDRDGRESFEWPALQ 479
>gi|157741853|gb|ABV69581.1| 6-phosphogluconate dehydrogenase [Leishmania lainsoni]
          Length = 479

 Score =  688 bits (1775), Expect = 0.0,   Method: Composition-based stats.
 Identities = 329/459 (71%), Positives = 387/459 (84%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEK FKVAV+NRT+SK++ F+K +    FA NL  +ETM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKHFKVAVYNRTHSKTQAFLKEHEHETFASNLHGYETMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+VF+ GDI++DTGNA+FKDQGRRA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVFDNGDIIIDTGNANFKDQGRRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYAILQ+W
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAILQVW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE ++ L+A+G NND+VA V E WKS  FLKSYMLDISIAA RAK+  G+YL+E V D I
Sbjct: 201 GEAYNALQALGFNNDQVADVFESWKSDGFLKSYMLDISIAACRAKEPAGNYLSEKVKDCI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVP+PSLNMAV+SRQ TM K ER AN    P    S    +K+K
Sbjct: 261 GSKGTGLWSAQEALEVGVPSPSLNMAVISRQMTMCKDERAANFKAFPTFPCSVREQVKDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE+KQLY +V ++II+ YAQMFQCLRE+DKV++FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNAPEVKQLYHAVSLSIIASYAQMFQCLRELDKVYDFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE NPN+ NLM AF  E++ GL  YR ++A++T+   VS+PV++ASL Y+ AM+
Sbjct: 381 IPMTKAFEANPNLPNLMDAFTKEMKEGLPAYRQIIAMLTASTAVSLPVMTASLAYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           TP L YGQLVSLQRDVFGRHGYER+DK+GRESF WP +Q
Sbjct: 441 TPILPYGQLVSLQRDVFGRHGYERIDKEGRESFTWPAMQ 479
>gi|72548846|ref|XP_843439.1| 6-phosphogluconate dehydrogenase, decarboxylating, putative
           [Leishmania major strain Friedlin]
 gi|14719820|gb|AAF64172.2| 6-phosphogluconate dehydrogenase [Leishmania major]
 gi|51922020|gb|AAU14136.1| 6-phosphogluconate dehydrogenase [Leishmania major]
 gi|51922024|gb|AAU14138.1| 6-phosphogluconate dehydrogenase [Leishmania major]
 gi|70905918|gb|AAZ14557.1| 6-phosphogluconate dehydrogenase, decarboxylating, putative
           [Leishmania major strain Friedlin]
          Length = 479

 Score =  686 bits (1770), Expect = 0.0,   Method: Composition-based stats.
 Identities = 332/459 (72%), Positives = 381/459 (83%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRTY+K+  F+K + S  FA NL  +ETM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTYAKTTSFLKEHESEKFAANLNGYETMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+VFE GDI++DTGNA+FKDQ +RA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVFENGDIIIDTGNANFKDQDKRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G +ND++A V E WK+  FLKSYMLDISIAA RA++  G+YL+E V DRI
Sbjct: 201 GEAYSALLAFGFDNDQIADVFESWKADGFLKSYMLDISIAACRAREATGNYLSEKVKDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALEIGVPAPSLNMAV+SRQ TMYK ER AN    P   + P     +K
Sbjct: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVISRQMTMYKGERIANCKAFPNFPRGPSEEATDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE K+LY +V + II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPEAKKLYHAVSLCIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NPN+ NLM AF  EI AGL + R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPNLPNLMDAFTKEIAAGLDDCRQILAKLTVNTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T TL YGQLVSLQRDVFGRHGYER DKDGRESF+WP LQ
Sbjct: 441 TETLPYGQLVSLQRDVFGRHGYERTDKDGRESFEWPALQ 479
>gi|165882000|gb|ABY71266.1| 6-phosphogluconate dehydrogenase [Leishmania amazonensis]
          Length = 479

 Score =  685 bits (1768), Expect = 0.0,   Method: Composition-based stats.
 Identities = 330/459 (71%), Positives = 382/459 (83%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRTY+K+  F+K + +   A NLK +ETM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTYTKTTSFLKEHENEALAVNLKGYETMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+VFE+GDI++DTGNA+FKDQ RRA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVFEEGDIVIDTGNANFKDQDRRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G NND++A V E WK+  FLKSYMLDISI A RA++  G+YL+E V+DRI
Sbjct: 201 GEAYSALLAFGFNNDQIADVFESWKADGFLKSYMLDISIVACRAREAAGNYLSEKVLDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSLNMAV+SRQ TMYK ER AN+   P     P     +K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLNMAVISRQMTMYKAERVANSKAFPHFPCGPCEKATDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE KQLY +V ++II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPEAKQLYHAVSLSIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NPN+ NLM AF  EI AGL + R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPNLPNLMDAFTKEIAAGLNDCRQILARLTVNTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T  L YGQLVSLQRDVFGRHGYER D+DGRESF+WP LQ
Sbjct: 441 TEILPYGQLVSLQRDVFGRHGYERTDRDGRESFEWPALQ 479
>gi|109450754|emb|CAJ43105.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           arabica]
          Length = 479

 Score =  683 bits (1762), Expect = 0.0,   Method: Composition-based stats.
 Identities = 330/459 (71%), Positives = 379/459 (82%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRTY+K+  F+K + S  FA NL  +ETM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTYAKTTSFLKEHESEKFAANLNGYETMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+VFE  DI++DTGNA+FKDQ +RA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVFENADIIIDTGNANFKDQDKRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNXGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G +ND++A V E WK+  FL+SYMLDISIAA RA++  G+YL+E V DRI
Sbjct: 201 GEAYSALLAFGFDNDQIADVFESWKADGFLRSYMLDISIAACRAREAAGNYLSEKVKDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSLNMAV+SRQ TMYK ER AN    P   + P     +K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLNMAVISRQMTMYKGERIANCKAFPNFPRGPSEEATDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE KQLY +V + II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPEAKQLYHAVSLCIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NPN+ NLM AF  EI AGL + R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPNLPNLMDAFTKEIAAGLDDCRQILAKLTVNTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T TL YGQLVSLQRDVFGRHGYER DKDGRESF+WP LQ
Sbjct: 441 TETLPYGQLVSLQRDVFGRHGYERTDKDGRESFEWPALQ 479
>gi|14719818|gb|AAF64171.2| 6-phosphogluconate dehydrogenase [Leishmania major]
 gi|51922022|gb|AAU14137.1| 6-phosphogluconate dehydrogenase [Leishmania major]
          Length = 479

 Score =  683 bits (1762), Expect = 0.0,   Method: Composition-based stats.
 Identities = 330/459 (71%), Positives = 380/459 (82%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRTY+K+  F+K + S  FA NL  + TM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTYAKTTSFLKEHESEKFAANLNGYGTMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+VFE GDI++DTGNA+FKDQ +RA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVFENGDIIIDTGNANFKDQDKRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G +ND++A V E WK+  FLKSYMLDIS+AA RA++  G+YL+E V DRI
Sbjct: 201 GEAYSALLAFGFDNDQIADVFESWKADGFLKSYMLDISVAACRAREATGNYLSEKVKDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALEIGVPAPSLNMAV+SRQ TMYK ER AN    P   + P     +K
Sbjct: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVISRQMTMYKGERIANCKAFPNFPRGPSEEATDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE K+LY +V + II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPEAKKLYHAVSLCIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NPN+ NLM AF  EI AGL + R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPNLPNLMDAFTKEIAAGLDDCRQILAKLTENTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T TL YGQLVSLQRDVFGRHGYER DKDGRESF+WP LQ
Sbjct: 441 TETLPYGQLVSLQRDVFGRHGYERTDKDGRESFEWPALQ 479
>gi|15625244|gb|AAL01643.1| 6-phosphogluconate dehydrogenase [Leishmania tropica]
          Length = 479

 Score =  682 bits (1761), Expect = 0.0,   Method: Composition-based stats.
 Identities = 330/459 (71%), Positives = 380/459 (82%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRTY+K+  F+K + S  FA NL  + TM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTYAKTTSFLKEHESEKFAANLNGYGTMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+VFE GDI++DTGNA+FKDQ +RA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVFENGDIIIDTGNANFKDQDKRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G +ND++A V E WK+  FLKSYMLDISIAA RA++  G+YL+E V DRI
Sbjct: 201 GEAYSALLAFGFDNDQIADVFESWKADGFLKSYMLDISIAACRAREATGNYLSEKVKDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALEIGVPAPSLNMAV+SRQ TMYK ER AN    P   + P     ++
Sbjct: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVISRQMTMYKGERIANCKAFPNFPRGPSEEATDR 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE K+LY +V + II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPEAKKLYHAVSLCIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NPN+ NLM AF  EI AGL + R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPNLPNLMDAFTKEIAAGLDDCRQILAKLTENTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T TL YGQLVSLQRDVFGRHGYER DKDGRESF+WP LQ
Sbjct: 441 TETLPYGQLVSLQRDVFGRHGYERTDKDGRESFEWPALQ 479
>gi|157741847|gb|ABV69578.1| 6-phosphogluconate dehydrogenase [Leishmania braziliensis]
          Length = 479

 Score =  682 bits (1759), Expect = 0.0,   Method: Composition-based stats.
 Identities = 329/459 (71%), Positives = 383/459 (83%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEK FKVAV+NRT SK+ +F+K +    FA NL+ +ETM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKHFKVAVYNRTCSKTHDFLKEHEHETFASNLQGYETMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK VFE GDI++DTGNA+FKDQ RRA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKVVFENGDIIIDTGNANFKDQSRRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAA+AKA+DGRPCVT NG GGAGSCVKMYHN+GEYAILQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAASAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAILQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L+A+G NND+VA V E WK+  FLKSYMLDISIAA RAK+  G+YL+E V D I
Sbjct: 201 GEAYSALQALGFNNDQVADVFESWKAGGFLKSYMLDISIAACRAKEPAGNYLSEKVKDCI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSLNMAV+SRQ TM K ER  N    P    S    +K+K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLNMAVISRQMTMCKDERAENFKAFPTFPCSVREQVKDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE+KQLY +V ++II+ YAQMFQCLRE+D+V+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNAPEVKQLYHAVSLSIIASYAQMFQCLRELDRVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NPN+ NLM AF  E++ GL  YR +VA++T+   VS+PV++ASL Y+ AM+
Sbjct: 381 IPMTKAFEENPNLPNLMDAFTKEMKEGLPAYRQIVAMLTASTAVSLPVMTASLAYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           TP L YGQLVSLQRDVFGRHGYERVDK+GRESF WP +Q
Sbjct: 441 TPILPYGQLVSLQRDVFGRHGYERVDKEGRESFTWPAMQ 479
>gi|154344979|ref|XP_001568431.1| 6-phosphogluconate dehydrogenase,decarboxylating, putative
           [Leishmania braziliensis MHOM/BR/75/M2904]
 gi|134065768|emb|CAM43542.1| 6-phosphogluconate dehydrogenase,decarboxylating, putative
           [Leishmania braziliensis]
 gi|157741843|gb|ABV69576.1| 6-phosphogluconate dehydrogenase [Leishmania braziliensis]
 gi|157741845|gb|ABV69577.1| 6-phosphogluconate dehydrogenase [Leishmania peruviana]
 gi|163963117|gb|ABY50510.1| 6-phosphogluconate dehydrogenase [Leishmania braziliensis]
 gi|163963121|gb|ABY50512.1| 6-phosphogluconate dehydrogenase [Leishmania braziliensis]
 gi|163963123|gb|ABY50513.1| 6-phosphogluconate dehydrogenase [Leishmania braziliensis]
 gi|163963125|gb|ABY50514.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963127|gb|ABY50515.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963129|gb|ABY50516.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963131|gb|ABY50517.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963133|gb|ABY50518.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963135|gb|ABY50519.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963137|gb|ABY50520.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963139|gb|ABY50521.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963141|gb|ABY50522.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963143|gb|ABY50523.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963145|gb|ABY50524.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963147|gb|ABY50525.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963149|gb|ABY50526.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
 gi|163963151|gb|ABY50527.1| 6-phosphogluconate dehydrogenase [Leishmania peruviana]
 gi|163963153|gb|ABY50528.1| 6-phosphogluconate dehydrogenase [Leishmania peruviana]
 gi|163963155|gb|ABY50529.1| 6-phosphogluconate dehydrogenase [Leishmania peruviana]
 gi|163963157|gb|ABY50530.1| 6-phosphogluconate dehydrogenase [Leishmania peruviana]
 gi|163963159|gb|ABY50531.1| 6-phosphogluconate dehydrogenase [Leishmania peruviana]
 gi|163963161|gb|ABY50532.1| 6-phosphogluconate dehydrogenase [Leishmania peruviana]
 gi|163963163|gb|ABY50533.1| 6-phosphogluconate dehydrogenase [Leishmania peruviana]
 gi|163963165|gb|ABY50534.1| 6-phosphogluconate dehydrogenase [Leishmania peruviana]
 gi|163963167|gb|ABY50535.1| 6-phosphogluconate dehydrogenase [Leishmania peruviana]
 gi|163963169|gb|ABY50536.1| 6-phosphogluconate dehydrogenase [Leishmania sp.]
          Length = 479

 Score =  681 bits (1758), Expect = 0.0,   Method: Composition-based stats.
 Identities = 330/459 (71%), Positives = 382/459 (83%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEK FKVAV+NRT SK+ +F+K +    FA NL+ +ETM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKHFKVAVYNRTCSKTHDFLKEHEHETFASNLQGYETMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK VFE GDI++DTGNA+FKDQ RRA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKVVFENGDIIIDTGNANFKDQSRRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAA+AKA+DGRPCVT NG GGAGSCVKMYHN+GEYAILQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAASAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAILQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L+A+G NND+VA V E WK+  FLKSYMLDISIAA RAK+  G+YL+E V D I
Sbjct: 201 GEAYSALQALGFNNDQVADVFESWKAGGFLKSYMLDISIAACRAKEPAGNYLSEKVKDCI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSLNMAV+SRQ TM K ER  N    P    S    +K+K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLNMAVISRQMTMCKDERAENFKAFPTFPCSVREQVKDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE+KQLY +V ++II+ YAQMFQCLRE+DKVH FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNAPEVKQLYHAVSLSIIASYAQMFQCLRELDKVHGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NPN+ NLM AF  E++ GL  YR +VA++T+   VS+PV++ASL Y+ AM+
Sbjct: 381 IPMTKAFEENPNLPNLMDAFTKEMKEGLPAYRQIVAMLTASTAVSLPVMTASLAYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T  L YGQLVSLQRDVFGRHGYERVDK+GRESF WP +Q
Sbjct: 441 TLILPYGQLVSLQRDVFGRHGYERVDKEGRESFTWPAMQ 479
>gi|163963119|gb|ABY50511.1| 6-phosphogluconate dehydrogenase [Leishmania braziliensis]
          Length = 479

 Score =  680 bits (1755), Expect = 0.0,   Method: Composition-based stats.
 Identities = 330/459 (71%), Positives = 381/459 (83%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEK FKVAV+NRT SK+ +F+K +    FA NL+ +ETM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKHFKVAVYNRTCSKTHDFLKEHEHETFASNLQGYETMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK VFE GDI++DTGNA+FKDQ RRA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKVVFENGDIIIDTGNANFKDQSRRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAA+AKA+DGRPCVT NG GGAGSCVKMYHN+GEYAILQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAASAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAILQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L+A+G NND+VA V E WK+  FLKSYMLDISIAA RAK+  G+YL+E V D I
Sbjct: 201 GEAYSALQALGFNNDQVADVFESWKAGGFLKSYMLDISIAACRAKEPAGNYLSEKVKDCI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSLNMAV+SRQ TM K ER  N    P    S     K+K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLNMAVISRQMTMCKDERAENFKAFPTFPCSVREQXKDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE+KQLY +V ++II+ YAQMFQCLRE+DKVH FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNAPEVKQLYHAVSLSIIASYAQMFQCLRELDKVHGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NPN+ NLM AF  E++ GL  YR +VA++T+   VS+PV++ASL Y+ AM+
Sbjct: 381 IPMTKAFEENPNLPNLMDAFTKEMKEGLPAYRQIVAMLTASTAVSLPVMTASLAYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T  L YGQLVSLQRDVFGRHGYERVDK+GRESF WP +Q
Sbjct: 441 TLILPYGQLVSLQRDVFGRHGYERVDKEGRESFTWPAMQ 479
>gi|157741851|gb|ABV69580.1| 6-phosphogluconate dehydrogenase [Leishmania panamensis]
          Length = 479

 Score =  678 bits (1750), Expect = 0.0,   Method: Composition-based stats.
 Identities = 328/459 (71%), Positives = 382/459 (83%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEK FKVAV+NRT SK+ +F+K +    FA NL+ +ETM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKHFKVAVYNRTCSKTHDFLKEHEHETFASNLQGYETMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK VFE GDI++DTGNA+FKDQ RRA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKVVFENGDIIIDTGNANFKDQSRRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAA+AKA+DGRPCVT NG GGAGSCVKMYHN+GEYAILQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAASAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAILQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L+A+G NND+VA V E WK+  FLKSYMLDISIAA RAK+  G+YL+E V D I
Sbjct: 201 GEAYSALQALGFNNDQVADVFESWKADGFLKSYMLDISIAACRAKEPAGNYLSEKVKDCI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSLNMAV+SRQ TM K ER  N    P    S    +K+K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLNMAVISRQMTMCKDERAENFKAFPTFPCSVREQVKDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE+KQLY +V ++II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNAPEVKQLYHAVSLSIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE NP++ NLM AF  E++ GL  YR ++A++T+K  VS+PV++ASL Y+ AM+
Sbjct: 381 IPMTKAFEANPHLPNLMDAFTKEMKEGLPAYRQIIAMLTAKTAVSLPVMTASLAYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T  L YGQLVSLQRDVFGRHGYERVDK+GRESF WP +Q
Sbjct: 441 TLILPYGQLVSLQRDVFGRHGYERVDKEGRESFTWPAMQ 479
>gi|157741849|gb|ABV69579.1| 6-phosphogluconate dehydrogenase [Leishmania guyanensis]
          Length = 479

 Score =  674 bits (1740), Expect = 0.0,   Method: Composition-based stats.
 Identities = 326/459 (71%), Positives = 380/459 (82%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEK FKVAV+NRT SK+ +F+K +    FA NL+ +ETM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAEKHFKVAVYNRTCSKTHDFLKEHEHETFASNLQGYETMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK VFE  DI++DTGNA+FKDQ RRA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKVVFENDDIIIDTGNANFKDQSRRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAA+AKA+DGRPCVT NG GGAGSCVKMYHN+GEYAILQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAASAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAILQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L+A+G NND+VA V E WK+  FLKSYMLDISIAA RAK+  G+YL+E V D I
Sbjct: 201 GEAYSALQALGFNNDQVADVFESWKADGFLKSYMLDISIAACRAKEPAGNYLSEKVKDCI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSLNMAV+SRQ TM K ER  N    P    S    +K+K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLNMAVISRQMTMCKDERAENFKAFPTFPCSVREQVKDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE+KQLY +V ++II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNAPEVKQLYHAVSLSIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE NP++ NLM AF  E++ GL  YR ++A++T+   VS+PV++ASL Y+ AM+
Sbjct: 381 IPMTKAFEANPHLPNLMDAFTKEMKEGLPAYRQIIAMLTANTAVSLPVMTASLAYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T  L YGQLVSLQRDVFGRHGYERVDK+GRESF WP +Q
Sbjct: 441 TLILPYGQLVSLQRDVFGRHGYERVDKEGRESFTWPAMQ 479
>gi|109450738|emb|CAJ43098.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
          Length = 479

 Score =  674 bits (1740), Expect = 0.0,   Method: Composition-based stats.
 Identities = 327/459 (71%), Positives = 380/459 (82%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRT +K+  F+K + S  FA NL  +ETM+AFAASLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTSAKTASFLKEHESKKFAANLNGYETMKAFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+V E GDI++DTGNA+FKDQ +RA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVLENGDIIIDTGNANFKDQDKRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G +ND++A V E WK+  FLKSYMLDISIAA RA++  G+YL+E V DRI
Sbjct: 201 GEAYTALLAFGFDNDQIADVFESWKADGFLKSYMLDISIAACRAREAAGNYLSEKVKDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSL+MAV+SRQ TM K ER AN    P   + P    ++K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLSMAVISRQMTMCKEERIANCKAFPNFPRGPSAEARDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ P+ KQLY +V + II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPDAKQLYHAVSLCIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NP++ NLM AF  EI AGL + R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPSLPNLMDAFTKEIVAGLDDCRQILAKLTVNTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T TL YGQLVSLQRDVFGRHGYER DKDGRESF+WP LQ
Sbjct: 441 TETLPYGQLVSLQRDVFGRHGYERTDKDGRESFEWPALQ 479
>gi|146101549|ref|XP_001469143.1| 6-phosphogluconate dehydrogenase,decarboxylating [Leishmania
           infantum]
 gi|109450680|emb|CAJ43070.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450682|emb|CAJ43071.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450684|emb|CAJ43072.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450686|emb|CAJ43073.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450688|emb|CAJ43074.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450690|emb|CAJ43075.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450692|emb|CAJ43076.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450694|emb|CAJ43077.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450696|emb|CAJ43078.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450698|emb|CAJ43079.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450700|emb|CAJ43080.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450708|emb|CAJ43083.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450710|emb|CAJ43084.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450712|emb|CAJ43085.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450714|emb|CAJ43086.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450720|emb|CAJ43089.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450722|emb|CAJ43090.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450724|emb|CAJ43091.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450726|emb|CAJ43092.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450740|emb|CAJ43099.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450742|emb|CAJ43100.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450744|emb|CAJ43101.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450746|emb|CAJ43102.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450748|emb|CAJ43103.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450750|emb|CAJ43104.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450752|emb|CAJ43108.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450800|emb|CAJ43270.1| phosphogluconate dehydrogenase [Leishmania infantum]
 gi|109450802|emb|CAJ43271.1| phosphogluconate dehydrogenase [Leishmania donovani]
 gi|109450804|emb|CAJ43272.1| phosphogluconate dehydrogenase [Leishmania donovani]
 gi|134073512|emb|CAM72244.1| 6-phosphogluconate dehydrogenase,decarboxylating, putative
           [Leishmania infantum]
          Length = 479

 Score =  674 bits (1740), Expect = 0.0,   Method: Composition-based stats.
 Identities = 327/459 (71%), Positives = 380/459 (82%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRT +K+  F+K + S  FA NL  +ETM+AFAASLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTSAKTASFLKEHESEKFAANLNGYETMKAFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+V E GDI++DTGNA+FKDQ +RA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVLENGDIIIDTGNANFKDQDKRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G +ND++A V E WK+  FLKSYMLDISIAA RA++  G+YL+E V DRI
Sbjct: 201 GEAYTALLAFGFDNDQIADVFESWKADGFLKSYMLDISIAACRAREAAGNYLSEKVKDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSL+MAV+SRQ TM K ER AN    P   + P    ++K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLSMAVISRQMTMCKEERIANCKAFPNFPRGPSAEARDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ P+ KQLY +V + II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPDAKQLYHAVSLCIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NP++ NLM AF  EI AGL + R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPSLPNLMDAFTKEIVAGLDDCRQILAKLTVNTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T TL YGQLVSLQRDVFGRHGYER DKDGRESF+WP LQ
Sbjct: 441 TETLPYGQLVSLQRDVFGRHGYERTDKDGRESFEWPALQ 479
>gi|109450702|emb|CAJ43081.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450704|emb|CAJ43107.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           infantum]
 gi|109450734|emb|CAJ43096.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
          Length = 479

 Score =  674 bits (1738), Expect = 0.0,   Method: Composition-based stats.
 Identities = 327/459 (71%), Positives = 379/459 (82%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRT +K+  F+K + S  FA NL  +ETM+AFAASLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTSAKTASFLKEHESEKFAANLNGYETMKAFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+V E GDI++DTGNA+FKDQ +RA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVLENGDIIIDTGNANFKDQDKRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G +ND++A V E WK+  FLKSYMLDISIAA RA++  G+YL+E V DRI
Sbjct: 201 GEAYTALLAFGFDNDQIADVFESWKADGFLKSYMLDISIAACRAREAAGNYLSEKVKDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSL+MAV+SRQ TM K ER AN    P   + P    ++K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLSMAVISRQMTMCKEERIANCKAFPNFPRGPSAEARDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ P  KQLY +V + II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPNAKQLYHAVSLCIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NP++ NLM AF  EI AGL + R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPSLPNLMDAFTKEIVAGLDDCRQILAKLTVNTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T TL YGQLVSLQRDVFGRHGYER DKDGRESF+WP LQ
Sbjct: 441 TETLPYGQLVSLQRDVFGRHGYERTDKDGRESFEWPALQ 479
>gi|37528837|gb|AAQ92344.1| 6-phosphogluconate dehydrogenase [Leishmania mexicana]
          Length = 479

 Score =  673 bits (1737), Expect = 0.0,   Method: Composition-based stats.
 Identities = 325/459 (70%), Positives = 378/459 (82%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAE GFKVAVFNRTY+K+  F+K + +     NLK +ETM+ FAASLKKPR+A ILVQAG
Sbjct: 21  IAENGFKVAVFNRTYTKTTSFLKEHENEALVVNLKGYETMKEFAASLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+VFE+GDI++DTGNA+FKDQ RRA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVFEEGDIVIDTGNANFKDQDRRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G NND++A V E WK+  FLKSYMLDISI A RA++  G+YL+E V+DRI
Sbjct: 201 GEAYSALLAFGFNNDQIADVFESWKADGFLKSYMLDISIVACRAREAAGNYLSEKVLDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSLNMAV+SRQ TMYK ER AN+   P     P     +K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLNMAVISRQMTMYKAERVANSKAFPHFPCGPCEKATDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ PE KQL+ +V ++II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPEAKQLFHAVSLSIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NPN+ NLM AF  EI AGL + R ++A +T    VS+  + ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPNLPNLMDAFTKEIAAGLNDCRQILARLTVNTAVSLAGMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T  L YGQLVSLQRDVFGRHGYER D+DGRESF+WP LQ
Sbjct: 441 TEILPYGQLVSLQRDVFGRHGYERTDRDGRESFEWPALQ 479
>gi|109450730|emb|CAJ43094.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450732|emb|CAJ43095.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
          Length = 479

 Score =  673 bits (1737), Expect = 0.0,   Method: Composition-based stats.
 Identities = 326/459 (71%), Positives = 379/459 (82%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRT +K+  F+K + S  FA NL  +ETM+AFA SLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTSAKTASFLKEHESEKFAANLNGYETMKAFAVSLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+V E GDI++DTGNA+FKDQ +RA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVLENGDIIIDTGNANFKDQDKRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G +ND++A V E WK+  FLKSYMLDISIAA RA++  G+YL+E V DRI
Sbjct: 201 GEAYTALLAFGFDNDQIADVFESWKADGFLKSYMLDISIAACRAREAAGNYLSEKVKDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSL+MAV+SRQ TM K ER AN    P   + P    ++K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLSMAVISRQMTMCKXERIANCKAFPNFPRGPSAEARDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ P+ KQLY +V + II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPDAKQLYHAVSLCIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NP++ NLM AF  EI AGL + R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPSLPNLMDAFTKEIVAGLDDCRQILAKLTVNTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T TL YGQLVSLQRDVFGRHGYER DKDGRESF+WP LQ
Sbjct: 441 TETLPYGQLVSLQRDVFGRHGYERTDKDGRESFEWPALQ 479
>gi|109450718|emb|CAJ43088.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450728|emb|CAJ43093.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450736|emb|CAJ43097.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
          Length = 479

 Score =  673 bits (1736), Expect = 0.0,   Method: Composition-based stats.
 Identities = 326/459 (71%), Positives = 379/459 (82%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRT +K+  F+K + S  FA NL  +ETM+AFA SLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTSAKTASFLKEHESEKFAANLNGYETMKAFAVSLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+V E GDI++DTGNA+FKDQ +RA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVLENGDIIIDTGNANFKDQDKRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G +ND++A V E WK+  FLKSYMLDISIAA RA++  G+YL+E V DRI
Sbjct: 201 GEAYTALLAFGFDNDQIADVFESWKADGFLKSYMLDISIAACRAREAAGNYLSEKVKDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSL+MAV+SRQ TM K ER AN    P   + P    ++K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLSMAVISRQMTMCKEERIANCKAFPNFPRGPSAEARDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ P+ KQLY +V + II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPDAKQLYHAVSLCIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NP++ NLM AF  EI AGL + R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPSLPNLMDAFTKEIVAGLDDCRQILAKLTVNTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T TL YGQLVSLQRDVFGRHGYER DKDGRESF+WP LQ
Sbjct: 441 TETLPYGQLVSLQRDVFGRHGYERTDKDGRESFEWPALQ 479
>gi|109450706|emb|CAJ43082.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
 gi|109450716|emb|CAJ43087.1| phosphogluconate dehydrogenase (decarboxylating) [Leishmania
           donovani]
          Length = 479

 Score =  673 bits (1736), Expect = 0.0,   Method: Composition-based stats.
 Identities = 326/459 (71%), Positives = 379/459 (82%)

Query: 21  IAEKGFKVAVFNRTYSKSEEFMKANASAPFAGNLKAFETMEAFAASLKKPRKALILVQAG 80
           IAEKGFKVAVFNRT +K+  F+K + S  FA NL  +ETM+AFA SLKKPR+A ILVQAG
Sbjct: 21  IAEKGFKVAVFNRTSAKTASFLKEHESEKFAANLNGYETMKAFAXSLKKPRRAFILVQAG 80

Query: 81  AATDSTTEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKG 140
           AATDST EQLK+V E GDI++DTGNA+FKDQ +RA QLE+ GLRFLGMGISGGEEGARKG
Sbjct: 81  AATDSTIEQLKEVLENGDIIIDTGNANFKDQDKRAAQLESQGLRFLGMGISGGEEGARKG 140

Query: 141 PAFFPGGTLSVWEEIRPIVEAAAAKADDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIW 200
           PAFFPGGT SVWEE+RPIVEAAAAKA+DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIW
Sbjct: 141 PAFFPGGTPSVWEEVRPIVEAAAAKAEDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIW 200

Query: 201 GEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRI 260
           GE +  L A G +ND++A V E WK+  FLKSYMLDISIAA RA++  G+YL+E V DRI
Sbjct: 201 GEAYTALLAFGFDNDQIADVFESWKADGFLKSYMLDISIAACRAREAAGNYLSEKVKDRI 260

Query: 261 GSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPGITQSPGYTLKNK 320
           GSKGTGLWSAQEALE+GVPAPSL+MAV+SRQ TM K ER AN    P   + P    ++K
Sbjct: 261 GSKGTGLWSAQEALEVGVPAPSLSMAVISRQMTMCKEERIANCKAFPNFPRGPSAEARDK 320

Query: 321 SPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLL 380
           SP+ P+ KQLY +V + II+ YAQMFQCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL
Sbjct: 321 SPNSPDAKQLYHAVSLCIIASYAQMFQCLRELDKVYGFGLNLPATIATFRAGCILQGYLL 380

Query: 381 KPMTEAFEKNPNISNLMCAFQTEIRAGLQNYRDMVALITSKLEVSIPVLSASLNYVTAMF 440
            PMT+AFE+NP++ NLM AF  EI AGL + R ++A +T    VS+PV+ ASL+Y+ AM+
Sbjct: 381 GPMTKAFEENPSLPNLMDAFTKEIVAGLDDCRQILAKLTVNTAVSLPVMMASLSYINAMY 440

Query: 441 TPTLKYGQLVSLQRDVFGRHGYERVDKDGRESFQWPELQ 479
           T TL YGQLVSLQRDVFGRHGYER DKDGRESF+WP LQ
Sbjct: 441 TETLPYGQLVSLQRDVFGRHGYERTDKDGRESFEWPALQ 479
>gi|109450806|emb|CAJ43273.1| phosphogluconate dehydrogenase [Leishmania donovani]
          Length = 435

 Score =  642 bits (1655), Expect = 0.0,   Method: Composition-based stats.
 Identities = 310/433 (71%), Positives = 359/433 (82%)

Query: 47  SAPFAGNLKAFETMEAFAASLKKPRKALILVQAGAATDSTTEQLKKVFEKGDILVDTGNA 106
           S  FA NL  +ETM+AFAASLKKPR+A ILVQAGAATDST EQLK+V E GDI++DTGNA
Sbjct: 3   SEKFAANLNGYETMKAFAASLKKPRRAFILVQAGAATDSTIEQLKEVLENGDIIIDTGNA 62

Query: 107 HFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKA 166
           +FKDQ +RA QLE+ GLRFLGMGISGGEEGARKGPAFFPGGT SVWEE+RPIVEAAAAKA
Sbjct: 63  NFKDQDKRAAQLESQGLRFLGMGISGGEEGARKGPAFFPGGTPSVWEEVRPIVEAAAAKA 122

Query: 167 DDGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKS 226
           +DGRPCVT NG GGAGSCVKMYHN+GEYA+LQIWGE +  L A G +ND++A V E WK+
Sbjct: 123 EDGRPCVTFNGKGGAGSCVKMYHNAGEYAVLQIWGEAYTALLAFGFDNDQIADVFESWKA 182

Query: 227 KNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMA 286
             FLKSYMLDISIAA RA++  G+YL+E V DRIGSKGTGLWSAQEALE+GVPAPSL+MA
Sbjct: 183 DGFLKSYMLDISIAACRAREAAGNYLSEKVKDRIGSKGTGLWSAQEALEVGVPAPSLSMA 242

Query: 287 VVSRQFTMYKTERQANASNAPGITQSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMF 346
           V+SRQ TM K ER AN    P   + P    ++KSP+ P+ KQLY +V + II+ YAQMF
Sbjct: 243 VISRQMTMCKEERIANCKAFPNFPRGPSAEARDKSPNSPDAKQLYHAVSLCIIASYAQMF 302

Query: 347 QCLREMDKVHNFGLNLPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLMCAFQTEIRA 406
           QCLRE+DKV+ FGLNLPATIATFRAGCILQGYLL PMT+AFE+NP++ NLM AF  EI A
Sbjct: 303 QCLRELDKVYGFGLNLPATIATFRAGCILQGYLLGPMTKAFEENPSLPNLMDAFTKEIVA 362

Query: 407 GLQNYRDMVALITSKLEVSIPVLSASLNYVTAMFTPTLKYGQLVSLQRDVFGRHGYERVD 466
           GL + R ++A +T    VS+PV+ ASL+Y+ AM+T TL YGQLVSLQRDVFGRHGYER D
Sbjct: 363 GLDDCRQILAKLTVNTAVSLPVMMASLSYINAMYTETLPYGQLVSLQRDVFGRHGYERTD 422

Query: 467 KDGRESFQWPELQ 479
           KDGRESF+WP LQ
Sbjct: 423 KDGRESFEWPALQ 435