BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= EAN77090__[Trypanosoma_brucei]
         (241 letters)

Database: nr.pal 
           6,348,806 sequences; 2,166,943,470 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71745580|ref|XP_827420.1|  Gim5B protein [Trypanosoma bru...   468   e-130
gi|8649001|emb|CAB94857.1|  GIM5B protein [Trypanosoma bruce...   465   e-130
gi|8649000|emb|CAB94856.1|  GIM5A protein [Trypanosoma bruce...   413   e-114
gi|71745578|ref|XP_827419.1|  Gim5A protein [Trypanosoma bru...   410   e-113
gi|71659858|ref|XP_821649.1|  Gim5A protein, putative [Trypa...   290   8e-77
gi|71403635|ref|XP_804598.1|  Gim5A protein, putative [Trypa...   289   1e-76
gi|71421782|ref|XP_811903.1|  Gim5A protein, putative [Trypa...   258   2e-67
gi|72549091|ref|XP_843475.1|  glycosomal membrane protein [L...   227   6e-58
gi|146101695|ref|XP_001469178.1|  Gim5A protein; glycosomal ...   223   1e-56
gi|154345059|ref|XP_001568471.1|  Gim5A protein, putative [L...   222   2e-56
gi|71403643|ref|XP_804602.1|  Gim5A protein, putative [Trypa...   178   2e-43
gi|154345057|ref|XP_001568470.1|  hypothetical protein LbrM3...    62   4e-08
gi|71403641|ref|XP_804601.1|  hypothetical protein Tc00.1047...    61   5e-08
gi|71421784|ref|XP_811904.1|  hypothetical protein Tc00.1047...    58   6e-07
gi|72549086|ref|XP_843474.1|  hypothetical protein, conserve...    46   0.002
gi|146101692|ref|XP_001469177.1|  hypothetical protein [Leis...    45   0.006
gi|110598086|ref|ZP_01386365.1|  hypothetical protein CferDR...    37   1.2  
gi|85708313|ref|ZP_01039379.1|  sulfate permease [Erythrobac...    36   2.5  
gi|85706030|ref|ZP_01037126.1|  sulfate permease [Roseovariu...    35   5.0  
>gi|71745580|ref|XP_827420.1| Gim5B protein [Trypanosoma brucei TREU927]
 gi|70831585|gb|EAN77090.1| Gim5B protein [Trypanosoma brucei]
          Length = 241

 Score =  468 bits (1203), Expect = e-130,   Method: Composition-based stats.
 Identities = 241/241 (100%), Positives = 241/241 (100%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
           VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF
Sbjct: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240

Query: 241 Y 241
           Y
Sbjct: 241 Y 241
>gi|8649001|emb|CAB94857.1| GIM5B protein [Trypanosoma brucei brucei]
          Length = 241

 Score =  465 bits (1197), Expect = e-130,   Method: Composition-based stats.
 Identities = 240/241 (99%), Positives = 240/241 (99%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKP GDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPAGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
           VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF
Sbjct: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240

Query: 241 Y 241
           Y
Sbjct: 241 Y 241
>gi|8649000|emb|CAB94856.1| GIM5A protein [Trypanosoma brucei brucei]
          Length = 243

 Score =  413 bits (1061), Expect = e-114,   Method: Composition-based stats.
 Identities = 218/243 (89%), Positives = 224/243 (92%), Gaps = 2/243 (0%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRG-HCTAAAASGDDKR-KTCPYGGCKRVMVDLL 178
           LSGVAVLCWMYTLVLGIVRQLY+  K+R    +  A +GDDK+     Y   KR  V+LL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYLFVKLRPRQASRGAGAGDDKKVPAYTYLELKRAFVNLL 180

Query: 179 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 238
           KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC
Sbjct: 181 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 240

Query: 239 EFY 241
           EFY
Sbjct: 241 EFY 243
>gi|71745578|ref|XP_827419.1| Gim5A protein [Trypanosoma brucei TREU927]
 gi|70831584|gb|EAN77089.1| Gim5A protein [Trypanosoma brucei]
          Length = 243

 Score =  410 bits (1053), Expect = e-113,   Method: Composition-based stats.
 Identities = 216/243 (88%), Positives = 222/243 (91%), Gaps = 2/243 (0%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRG-HCTAAAASGDDKR-KTCPYGGCKRVMVDLL 178
           LSGVAVLCWMYTL LGIVRQLY+  K+R    +  A +GDDK+     Y   KR  V+LL
Sbjct: 121 LSGVAVLCWMYTLALGIVRQLYLFVKLRPRQASRGAGAGDDKKVPAYTYLELKRAFVNLL 180

Query: 179 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 238
           KLVCYFLFALTCLPEGKPQLLANA GPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC
Sbjct: 181 KLVCYFLFALTCLPEGKPQLLANARGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 240

Query: 239 EFY 241
           EFY
Sbjct: 241 EFY 243
>gi|71659858|ref|XP_821649.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gi|70887033|gb|EAN99798.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 244

 Score =  290 bits (741), Expect = 8e-77,   Method: Composition-based stats.
 Identities = 154/245 (62%), Positives = 189/245 (77%), Gaps = 5/245 (2%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA AHTYL D WNRDKVMAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTR
Sbjct: 1   MSACAHTYLSDTWNRDKVMAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLL NALS  TL  L+KP GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R
Sbjct: 61  LSLLLNALSSKTLKDLTKPKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVD 176
             GVAV+CW+YTL+LGI RQ Y+L+K   RG C A     D ++K  PY    CKR +V+
Sbjct: 121 FGGVAVVCWLYTLLLGIARQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVN 179

Query: 177 LLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIAS 236
           L+K+ C+ +FA+TCLPEG+P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS
Sbjct: 180 LVKMSCFAVFAMTCLPEGRPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATAS 239

Query: 237 VCEFY 241
           +C+FY
Sbjct: 240 LCDFY 244
>gi|71403635|ref|XP_804598.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gi|70867653|gb|EAN82747.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 244

 Score =  289 bits (739), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 154/245 (62%), Positives = 189/245 (77%), Gaps = 5/245 (2%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA AHTYL D WNRDKVMAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTR
Sbjct: 1   MSACAHTYLSDTWNRDKVMAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLL NALS  TL  L+KP GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R
Sbjct: 61  LSLLLNALSSKTLKDLAKPKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVD 176
             GVAV+CW+YTL+LGI RQ Y+L+K   RG C A     D ++K  PY    CKR +V+
Sbjct: 121 FGGVAVVCWLYTLLLGIARQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVN 179

Query: 177 LLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIAS 236
           L+K+ C+ +FA+TCLPEG+P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS
Sbjct: 180 LVKMSCFAVFAMTCLPEGRPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATAS 239

Query: 237 VCEFY 241
           +C+FY
Sbjct: 240 LCDFY 244
>gi|71421782|ref|XP_811903.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gi|70876620|gb|EAN90052.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 226

 Score =  258 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 139/227 (61%), Positives = 174/227 (76%), Gaps = 5/227 (2%)

Query: 19  MAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSLSK 78
           MAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTRLSLL NALS  TL  L+K
Sbjct: 1   MAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTRLSLLLNALSSKTLKDLTK 60

Query: 79  PTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLVLGIV 138
           P GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R  GVAV+CW+YTL+LGI 
Sbjct: 61  PKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTRFGGVAVVCWLYTLLLGIA 120

Query: 139 RQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVDLLKLVCYFLFALTCLPEG 194
           RQ Y+L+K   RG C A     D ++K  PY    CKR +V+L+K+ C+ +FA+TCLPEG
Sbjct: 121 RQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVNLVKMSCFAVFAMTCLPEG 179

Query: 195 KPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEFY 241
           +P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS+C+FY
Sbjct: 180 RPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATASLCDFY 226
>gi|72549091|ref|XP_843475.1| glycosomal membrane protein [Leishmania major strain Friedlin]
 gi|70905954|gb|AAZ14593.1| glycosomal membrane protein [Leishmania major strain Friedlin]
          Length = 225

 Score =  227 bits (578), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 129/241 (53%), Positives = 166/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSAAVFEYLGNTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSSMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P    R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDVLLDRVDQLSHFFHVCFCFFENTAVLSSHNVYPNRFVR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++               K+K  P    KR MV  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMT---------------KKKNTPEEQ-KRQMVTTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPLVPLH  ++ ++P  L  ++T+RG+LG IAS+C+F
Sbjct: 165 GCFLIFSLTCFPKGGPQLLEDVSGPLVPLHKTLQLIAPKHLELNDTIRGVLGFIASMCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>gi|146101695|ref|XP_001469178.1| Gim5A protein; glycosomal membrane protein [Leishmania infantum]
 gi|134073547|emb|CAM72280.1| Gim5A protein, putative; glycosomal membrane protein [Leishmania
           infantum]
          Length = 225

 Score =  223 bits (567), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 128/241 (53%), Positives = 165/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSAAVFEYLGNTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSSMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P    R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDVLLDRVDQLSHFFHVCFCFFENTAVLSSHNVYPNRFVR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++               ++K  P    KR MV  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMT---------------QKKNTPEEQ-KRQMVTTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPLVPLH  ++ ++P  L  ++T+RG LG IAS+C+F
Sbjct: 165 GCFLIFSLTCFPKGGPQLLEDVSGPLVPLHKTLQLIAPKHLGLNDTIRGALGFIASMCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>gi|154345059|ref|XP_001568471.1| Gim5A protein, putative [Leishmania braziliensis MHOM/BR/75/M2904]
 gi|134065808|emb|CAM43585.1| Gim5A protein, putative; glycosomal membrane protein [Leishmania
           braziliensis]
          Length = 225

 Score =  222 bits (565), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 127/241 (52%), Positives = 166/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSASVFQYLANTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSTMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P  L R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDILLDRLDQLSHFFHVCFCFFENTAVLSSHNVYPSRLGR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++               ++K  P    KR M+  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMT---------------QKKNTPEEH-KRQMITTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPL+PLH  ++ ++P  L  ++T+RG LG IAS+C+F
Sbjct: 165 GCFLVFSLTCFPKGGPQLLEDVSGPLMPLHKTLQLIAPKCLELNDTIRGALGFIASLCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>gi|71403643|ref|XP_804602.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gi|70867657|gb|EAN82751.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 161

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 90/159 (56%), Positives = 118/159 (74%), Gaps = 5/159 (3%)

Query: 87  RIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLVLGIVRQLYMLSK 146
           R++Q+SH FHIGFCLNE+TAVLAG GV    L R  GVAV+CW+YTL+LGI RQ Y+L+K
Sbjct: 4   RLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTRFGGVAVVCWLYTLLLGIARQAYLLAK 63

Query: 147 M--RGHCTAAAASGDDKRKTCPYGG--CKRVMVDLLKLVCYFLFALTCLPEGKPQLLANA 202
              RG C A     D ++K  PY    CKR +V+L+K+ C+ +FA TCLPEG+P+LL + 
Sbjct: 64  HSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVNLVKMSCFAVFAKTCLPEGRPKLLQDV 122

Query: 203 SGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEFY 241
            GPLVPLH +++A++PN LH S+TVRGLL   AS+C+FY
Sbjct: 123 CGPLVPLHELIRAIAPNKLHLSDTVRGLLAATASLCDFY 161
>gi|154345057|ref|XP_001568470.1| hypothetical protein LbrM34_V2.3670 [Leishmania braziliensis
           MHOM/BR/75/M2904]
 gi|134065807|emb|CAM43584.1| hypothetical protein, conserved [Leishmania braziliensis]
          Length = 253

 Score = 61.6 bits (148), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 72/250 (28%), Positives = 111/250 (44%), Gaps = 24/250 (9%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS 62
           A  + Y+ +  NRD+VM++VQF  MAL GPA  AGC  L+     +  +   YR +TR S
Sbjct: 11  ATFNDYIGNVSNRDRVMSVVQFSAMALTGPAAAAGCSKLSAHFNTIHHIAAHYRTITRFS 70

Query: 63  ---LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHG-----VF 114
              ++A AL+   +T       + +      +S  F   F + E   VLA        V 
Sbjct: 71  QWLVVAPALTYSGITGALNSHPNPLVGICKTISTAFFTVFLIGEEL-VLASKSNMLDPVL 129

Query: 115 PKSLHRLSGVAVLCWMYTLVLGIVRQL--YMLSKMRGHCTAAAASGDDKRKTCPYGGCKR 172
            K L+R+  V  L W       I R +  Y+L K   +        + K K         
Sbjct: 130 GKHLNRIRFV-FLFWS-----NIARLIMNYLLLKSSSYDAVKDTQNEKKAKDHRRKVLSV 183

Query: 173 VMVDLLKLVCYFLFALTCLPEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGL 230
               L  + CY L   +  P G P+ L+ A  SG +V +   + +L+P  +   +T +G+
Sbjct: 184 ADGVLQSMFCYTLLK-SSAPAG-PKYLSAALQSGNVVDV---ITSLAPPLIAVPSTPQGI 238

Query: 231 LGLIASVCEF 240
           +GL+ASV  F
Sbjct: 239 IGLVASVPGF 248
>gi|71403641|ref|XP_804601.1| hypothetical protein Tc00.1047053510669.9 [Trypanosoma cruzi strain
           CL Brener]
 gi|70867656|gb|EAN82750.1| hypothetical protein, conserved [Trypanosoma cruzi]
          Length = 247

 Score = 61.2 bits (147), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 61/243 (25%), Positives = 107/243 (44%), Gaps = 16/243 (6%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS 62
           A  H+YL  AW RD+V A++QF  M + G A + G  S+  S  +LAR+   Y +VTR+ 
Sbjct: 4   ALPHSYLSIAWRRDRVTAVLQFCSMVVSGVAGSVGQRSIERSAKSLARLLSEYGSVTRVC 63

Query: 63  -----LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKS 117
                LL  + +    T  + P      +RI  ++ +F   F  +E   +LA  GV  K 
Sbjct: 64  NWLVVLLELSPAGVRRTMRASPGFFTGIARI--VTTIFLGLFLASEEVELLAAGGVLSKV 121

Query: 118 L--HRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMV 175
              H    V +  + Y L+        + +  R      +    D +        K + +
Sbjct: 122 WRPHAARMVPIFFFYYNLLKAGTSAALLQAMQR-----ISFEATDTQSVIRKRHYKELFL 176

Query: 176 DLLKLVCYFLFALTCLPEGKPQL--LANASGPLVPLHVMVKALSPNPLHASNTVRGLLGL 233
             ++ + + ++A+T LP   P+L    N    +  ++ +  +L P  +      +GLLGL
Sbjct: 177 SFMEGIAFMVYAMTLLPSNAPRLREALNEGLWMDRVYSVFSSLCPQAVQVRPATQGLLGL 236

Query: 234 IAS 236
           +A+
Sbjct: 237 LAT 239
>gi|71421784|ref|XP_811904.1| hypothetical protein Tc00.1047053507009.20 [Trypanosoma cruzi
           strain CL Brener]
 gi|70876621|gb|EAN90053.1| hypothetical protein, conserved [Trypanosoma cruzi]
          Length = 247

 Score = 57.8 bits (138), Expect = 6e-07,   Method: Composition-based stats.
 Identities = 62/246 (25%), Positives = 106/246 (43%), Gaps = 22/246 (8%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR-- 60
           A  H+ L  AW RD+V A++QF  M + G A + G  S+  S  +LAR+   Y +VTR  
Sbjct: 4   ALPHSCLSIAWRRDRVPAVLQFCSMVVSGVAGSVGHRSIERSAKSLARLLSEYGSVTRVC 63

Query: 61  ------LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVF 114
                 L L    + +   TS    TG    +RI  ++ +F   F  +E   +LA  GV 
Sbjct: 64  NWLVVLLELSPAGVRRTMRTSPGFFTG---IARI--VTTIFLGLFLASEEVELLAAGGVL 118

Query: 115 PK--SLHRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKR 172
            K    H    V +  + Y L+        + +  R      +    D +        K 
Sbjct: 119 SKLWRPHAARMVPIFFFYYNLLKAATSAALLQAMQR-----ISFEATDTQSVIRKRHYKE 173

Query: 173 VMVDLLKLVCYFLFALTCLPEGKPQL--LANASGPLVPLHVMVKALSPNPLHASNTVRGL 230
           + +  ++ + + ++A+T LP   P+L    N    +  ++ +  +L P  +      +GL
Sbjct: 174 LFLSFMEGIAFMVYAMTLLPSNAPRLREALNEGFWMDRVYSVFSSLCPQAVQVRPATQGL 233

Query: 231 LGLIAS 236
           LGL+A+
Sbjct: 234 LGLLAT 239
>gi|72549086|ref|XP_843474.1| hypothetical protein, conserved [Leishmania major strain Friedlin]
 gi|70905953|gb|AAZ14592.1| hypothetical protein, conserved [Leishmania major strain Friedlin]
          Length = 253

 Score = 45.8 bits (107), Expect = 0.002,   Method: Composition-based stats.
 Identities = 64/240 (26%), Positives = 105/240 (43%), Gaps = 10/240 (4%)

Query: 6   HTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS--- 62
           + Y+ +A NRD+VM++VQF  MAL  PA  AGC  L+  L  +      YR VTR S   
Sbjct: 14  NNYVGNASNRDRVMSVVQFGAMALAAPAAAAGCPELSAHLSTILHGAAHYRTVTRFSQWL 73

Query: 63  LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLS 122
           ++A AL+   + S      +++      +S  F   F + E   + +   +    L +  
Sbjct: 74  VVAPALTPSGIKSAIASHPNLLVGICKTISTAFFTVFLIGEELVLASKCNMLDPVLGKRF 133

Query: 123 GVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKLVC 182
                 +++   +  +   Y+L K   +        ++K K             L  + C
Sbjct: 134 NRIRFVFLFWSNIARLVMSYLLLKSSKYDAVKDNQNEEKAKDHRRKVLGVADGVLQSMFC 193

Query: 183 YFLFALTCLPEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
           Y L   +  P G P+ L+ A  SG  V +   + +L+P  L   +T +G+LGL ASV  F
Sbjct: 194 YTLLK-SSAPAG-PKYLSAALRSGKAVDI---ITSLAPPLLVVPSTPQGMLGLAASVPGF 248
>gi|146101692|ref|XP_001469177.1| hypothetical protein [Leishmania infantum]
 gi|134073546|emb|CAM72279.1| hypothetical protein, conserved [Leishmania infantum]
          Length = 253

 Score = 44.7 bits (104), Expect = 0.006,   Method: Composition-based stats.
 Identities = 73/249 (29%), Positives = 114/249 (45%), Gaps = 32/249 (12%)

Query: 8   YLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS---LL 64
           Y+ +A NRD+VM++VQF  MAL  PA  AGC  L+     +      YR VTR S   ++
Sbjct: 16  YVGNASNRDRVMSVVQFGAMALVAPAAAAGCPELSAHFDTILHGAAHYRTVTRFSQWLVV 75

Query: 65  ANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGH-----GVFPKSLH 119
           A AL+   + S+     + +      +S  F   F + E   VLA        VF +  +
Sbjct: 76  APALTPSGIKSVIASHPNPLVGICKTISTAFFTVFLIGEEL-VLASKCNMLDPVFGRHFN 134

Query: 120 RLSGVAVLCW--MYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDL 177
           R+  V  L W  +  LV+      Y+L K   +     +  ++K K       +R ++++
Sbjct: 135 RIRFV-FLFWSNIARLVMN-----YLLLKSSKYDAVKDSQNEEKAKD-----HRRKVLNV 183

Query: 178 LKLVCYFLFALTCL----PEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGLL 231
              V   +F  T L    P G P+ L+ A  SG  V +   + +L+P      +T +G+L
Sbjct: 184 ADGVLQSMFCYTLLKSSAPAG-PKYLSAALRSGKAVDI---ITSLAPPLFVVPSTPQGML 239

Query: 232 GLIASVCEF 240
           GL ASV  F
Sbjct: 240 GLAASVPGF 248
>gi|110598086|ref|ZP_01386365.1| hypothetical protein CferDRAFT_0813 [Chlorobium ferrooxidans DSM
           13031]
 gi|110340345|gb|EAT58839.1| hypothetical protein CferDRAFT_0813 [Chlorobium ferrooxidans DSM
           13031]
          Length = 2110

 Score = 37.0 bits (84), Expect = 1.2,   Method: Composition-based stats.
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 191 LPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLL 231
           L    P++ ANA    VPLH +++AL PNP    N +  LL
Sbjct: 491 LSSQNPRVQANALSIKVPLHEILRALGPNPTTVDNAISNLL 531
>gi|85708313|ref|ZP_01039379.1| sulfate permease [Erythrobacter sp. NAP1]
 gi|85689847|gb|EAQ29850.1| sulfate permease [Erythrobacter sp. NAP1]
          Length = 588

 Score = 35.8 bits (81), Expect = 2.5,   Method: Composition-based stats.
 Identities = 36/147 (24%), Positives = 61/147 (41%), Gaps = 15/147 (10%)

Query: 19  MAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVT---RLSLLANALSKPTLTS 75
           +A++  +  +  G     G      +   LA +  A  A+    R   LAN LS P ++ 
Sbjct: 80  VAVISLMTASAAGSVAAQGTAEYLEAAITLAMLSGAMLAILGLLRAGFLANLLSHPVISG 139

Query: 76  LSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLVL 135
               +G ++A+   Q+ H+            V AG   +P  L  L+       ++TLV+
Sbjct: 140 FITASGILIAT--SQIKHIL----------GVDAGGDTWPAMLGSLAVAVGDTNVWTLVI 187

Query: 136 GIVRQLYMLSKMRGHCTAAAASGDDKR 162
           GI   L++    +G  +A  A G  KR
Sbjct: 188 GIPATLFLFWVRKGGSSALQAIGLRKR 214
>gi|85706030|ref|ZP_01037126.1| sulfate permease [Roseovarius sp. 217]
 gi|85669618|gb|EAQ24483.1| sulfate permease [Roseovarius sp. 217]
          Length = 584

 Score = 34.7 bits (78), Expect = 5.0,   Method: Composition-based stats.
 Identities = 37/125 (29%), Positives = 56/125 (44%), Gaps = 8/125 (6%)

Query: 19  MAIVQFLPMALEG---PARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTS 75
           +A+V  +  A  G    A TAG    AL+L  L+ +      + RL  LAN LS P +  
Sbjct: 81  VAVVSLMTAAAIGDVAEAGTAGYAVAALTLAGLSGLILLTMGILRLGFLANFLSHPVIAG 140

Query: 76  LSKPTGDMVASRIDQLSHLFHI---GFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYT 132
               +G ++A  + QL HL  +   G  L +    L  H     SL  L GVA   +++ 
Sbjct: 141 FITASGILIA--VSQLKHLLGVKASGGSLPDMLWSLLWHLADINSLTLLIGVASAAFLFW 198

Query: 133 LVLGI 137
           +  G+
Sbjct: 199 VRRGL 203