BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= EAN78432.1__[Trypanosoma_brucei]
(492 letters)
Database: nr.pal
6,348,806 sequences; 2,166,943,470 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71748410|ref|XP_823260.1| trypanothione reductase [Trypa... 981 0.0
gi|731029|sp|P39051|TYTR_TRYBB Trypanothione reductase (TR)... 964 0.0
gi|136619|sp|P13110|TYTR_TRYCO Trypanothione reductase (TR)... 865 0.0
gi|640319|pdb|1NDA|A Chain A, The Structure Of Trypanosoma ... 836 0.0
gi|136620|sp|P28593|TYTR_TRYCR Trypanothione reductase (TR)... 836 0.0
gi|71405339|ref|XP_805296.1| trypanothione reductase [Trypa... 833 0.0
gi|49258301|pdb|1GXF|A Chain A, Crystal Structure Of Trypan... 832 0.0
gi|6573510|pdb|1BZL|A Chain A, Crystal Structure Of Trypano... 831 0.0
gi|2554795|pdb|1AOG|A Chain A, Trypanosoma Cruzi Trypanothi... 829 0.0
gi|552297|gb|AAB59211.1| trypanothione reductase [Trypanoso... 767 0.0
gi|14600050|gb|AAK71224.1|AF359006_1 trypanothione reductas... 734 0.0
gi|14600010|gb|AAK71204.1|AF358986_1 trypanothione reductas... 727 0.0
gi|14600014|gb|AAK71206.1|AF358988_1 trypanothione reductas... 727 0.0
gi|14600022|gb|AAK71210.1|AF358992_1 trypanothione reductas... 727 0.0
gi|14600000|gb|AAK71199.1|AF358981_1 trypanothione reductas... 725 0.0
gi|14599976|gb|AAK71187.1|AF358969_1 trypanothione reductas... 725 0.0
gi|61207374|gb|AAX40409.1| trypanothione reductase [Trypano... 725 0.0
gi|61207342|gb|AAX40393.1| trypanothione reductase [Trypano... 725 0.0
gi|61207372|gb|AAX40408.1| trypanothione reductase [Trypano... 725 0.0
gi|14600018|gb|AAK71208.1|AF358990_1 trypanothione reductas... 724 0.0
gi|61207354|gb|AAX40399.1| trypanothione reductase [Trypano... 724 0.0
gi|14599980|gb|AAK71189.1|AF358971_1 trypanothione reductas... 724 0.0
gi|14600054|gb|AAK71226.1|AF359008_1 trypanothione reductas... 724 0.0
gi|61207360|gb|AAX40402.1| trypanothione reductase [Trypano... 722 0.0
gi|61207376|gb|AAX40410.1| trypanothione reductase [Trypano... 722 0.0
gi|61207356|gb|AAX40400.1| trypanothione reductase [Trypano... 722 0.0
gi|61207340|gb|AAX40392.1| trypanothione reductase [Trypano... 721 0.0
gi|61207352|gb|AAX40398.1| trypanothione reductase [Trypano... 721 0.0
gi|61207368|gb|AAX40406.1| trypanothione reductase [Trypano... 719 0.0
gi|61207370|gb|AAX40407.1| trypanothione reductase [Trypano... 718 0.0
gi|494695|pdb|1TYP|A Chain A, Substrate Interactions Betwee... 712 0.0
gi|731027|sp|P39040|TYTR_CRIFA Trypanothione reductase (TR)... 712 0.0
gi|1942669|pdb|1FEA|A Chain A, Unliganded Crithidia Fascicu... 709 0.0
gi|576321|pdb|1TYT|A Chain A, Crystal And Molecular Structu... 709 0.0
gi|162505|gb|AAA30322.1| trypanothione reductase 706 0.0
gi|443440|pdb|2TPR|A Chain A, X-Ray Structure Of Trypanothi... 706 0.0
gi|162507|gb|AAA30323.1| trypanothione reductase 706 0.0
gi|154332065|ref|XP_001561849.1| trypanothione reductase [L... 691 0.0
gi|146076772|ref|XP_001462998.1| trypanothione reductase [L... 674 0.0
gi|157863924|ref|XP_001687512.1| trypanothione reductase [L... 672 0.0
gi|148283954|gb|ABQ57410.1| trypanothione reductase [Leishm... 660 0.0
gi|731028|sp|P39050|TYTR_LEIDO Trypanothione reductase (TR)... 657 0.0
gi|71400296|ref|XP_803005.1| trypanothione reductase, putat... 655 0.0
gi|104745490|gb|ABF74601.1| trypanothione reductase [Leishm... 634 e-180
gi|16076075|emb|CAC94295.1| trypanothione reductase [Leishm... 557 e-157
gi|552306|gb|AAA30321.1| trypanothione reductase 540 e-152
gi|20799665|gb|AAM28598.1| putative trypanothione reductase... 427 e-118
gi|149921597|ref|ZP_01910047.1| glutathione-disulfide reduc... 350 2e-94
gi|146307376|ref|YP_001187841.1| glutathione reductase [Pse... 350 2e-94
gi|163794292|ref|ZP_02188264.1| glutathione-disulfide reduc... 347 2e-93
gi|152987683|ref|YP_001348623.1| glutathione reductase [Pse... 343 2e-92
gi|154247152|ref|YP_001418110.1| glutathione-disulfide redu... 342 4e-92
gi|70730762|ref|YP_260503.1| glutathione reductase [Pseudom... 340 1e-91
gi|116049975|ref|YP_791214.1| glutathione reductase [Pseudo... 340 2e-91
gi|157348053|emb|CAO22640.1| unnamed protein product [Vitis... 340 2e-91
gi|75675416|ref|YP_317837.1| glutathione reductase [Nitroba... 339 3e-91
gi|2425107|gb|AAB70837.1| glutathione reductase (NADPH) [Vi... 339 4e-91
gi|33596017|ref|NP_883660.1| glutathione reductase [Bordete... 338 4e-91
gi|147784400|emb|CAN66042.1| hypothetical protein [Vitis vi... 338 4e-91
gi|28871394|ref|NP_794013.1| glutathione reductase [Pseudom... 338 7e-91
gi|163857235|ref|YP_001631533.1| probable glutathione reduc... 338 7e-91
gi|15597221|ref|NP_250715.1| glutathione reductase [Pseudom... 337 9e-91
gi|33601404|ref|NP_888964.1| glutathione reductase [Bordete... 337 1e-90
gi|92117035|ref|YP_576764.1| Glutathione reductase [Nitroba... 337 1e-90
gi|157362217|dbj|BAF80308.1| chloroplastic glutathione redu... 336 3e-90
gi|33593132|ref|NP_880776.1| glutathione reductase [Bordete... 335 4e-90
gi|77459153|ref|YP_348659.1| glutathione reductase [Pseudom... 335 6e-90
gi|89093142|ref|ZP_01166092.1| glutathione reductase [Ocean... 335 6e-90
gi|115450913|ref|NP_001049057.1| Os03g0163300 [Oryza sativa... 334 9e-90
gi|152980459|ref|YP_001352656.1| glutathione reductase (NAD... 334 1e-89
gi|83592021|ref|YP_425773.1| Glutathione reductase [Rhodosp... 333 1e-89
gi|168003165|ref|XP_001754283.1| predicted protein [Physcom... 333 1e-89
gi|158423958|ref|YP_001525250.1| glutathione reductase [Azo... 333 1e-89
gi|1708059|sp|P80461|GSHRP_TOBAC Glutathione reductase, chl... 333 2e-89
gi|13448672|gb|AAK27157.1|AF349449_1 glutathione reductase ... 333 2e-89
gi|6714837|gb|AAF26175.1|AF105199_1 glutathione reductase [... 333 2e-89
gi|83310765|ref|YP_421029.1| Glutathione reductase [Magneto... 333 2e-89
gi|13470737|ref|NP_102306.1| glutathione reductase [Mesorhi... 332 3e-89
gi|46201169|ref|ZP_00207996.1| COG1249: Pyruvate/2-oxogluta... 332 4e-89
gi|118588078|ref|ZP_01545488.1| glutathione reductase [Stap... 332 5e-89
gi|167034531|ref|YP_001669762.1| glutathione-disulfide redu... 332 5e-89
gi|86750495|ref|YP_486991.1| Glutathione reductase [Rhodops... 331 7e-89
gi|146282467|ref|YP_001172620.1| glutathione reductase [Pse... 331 7e-89
gi|170722359|ref|YP_001750047.1| glutathione-disulfide redu... 331 8e-89
gi|1346192|sp|P48640|GSHRP_SOYBN Glutathione reductase, chl... 331 1e-88
gi|26990524|ref|NP_745949.1| glutathione reductase [Pseudom... 331 1e-88
gi|67154096|ref|ZP_00415841.1| FAD-dependent pyridine nucle... 330 1e-88
gi|4704611|gb|AAD28177.1|AF109694_1 glutathione reductase [... 329 2e-88
gi|144899594|emb|CAM76458.1| Glutathione reductase, plant [... 329 3e-88
gi|148547175|ref|YP_001267277.1| glutathione reductase [Pse... 329 3e-88
gi|115372506|ref|ZP_01459814.1| glutathione-disulfide reduc... 328 4e-88
gi|153009424|ref|YP_001370639.1| glutathione-disulfide redu... 328 7e-88
gi|94494357|gb|ABF29525.1| dual-targeted glutathione reduct... 327 1e-87
gi|163759647|ref|ZP_02166732.1| glutathione reductase [Hoef... 327 1e-87
gi|2500115|sp|Q43154|GSHRP_SPIOL Glutathione reductase, chl... 326 3e-87
gi|154251549|ref|YP_001412373.1| glutathione-disulfide redu... 325 3e-87
gi|15451194|gb|AAK96868.1| Gluthatione reductase, chloropla... 325 3e-87
gi|161511140|ref|NP_539889.2| glutathione reductase [Brucel... 325 3e-87
gi|62289935|ref|YP_221728.1| glutathione reductase [Brucell... 325 3e-87
gi|23501892|ref|NP_698019.1| glutathione reductase [Brucell... 325 4e-87
>gi|71748410|ref|XP_823260.1| trypanothione reductase [Trypanosoma brucei TREU927]
gi|70832928|gb|EAN78432.1| trypanothione reductase [Trypanosoma brucei]
Length = 492
Score = 981 bits (2535), Expect = 0.0, Method: Composition-based stats.
Identities = 479/492 (97%), Positives = 479/492 (97%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK
Sbjct: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL
Sbjct: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE
Sbjct: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK
Sbjct: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG
Sbjct: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT
Sbjct: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIXXXXXXXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLI YMSSFTPLMHNISGSKYKKFVAKIVTNHS
Sbjct: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
Query: 481 GEKMEKLPDSNL 492
GEKMEKLPDSNL
Sbjct: 481 GEKMEKLPDSNL 492
>gi|731029|sp|P39051|TYTR_TRYBB Trypanothione reductase (TR) (N(1),N(8)-bis(glutathionyl)spermidine
reductase)
gi|10545|emb|CAA44870.1| trypanothione reductase [Trypanosoma brucei]
Length = 492
Score = 964 bits (2492), Expect = 0.0, Method: Composition-based stats.
Identities = 469/492 (95%), Positives = 474/492 (96%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEAGWNAATLY KRVAV+DVQT HGPP YAALGGTCVNVGCVPK
Sbjct: 1 MSKIFDLVVIGAGSGGLEAGWNAATLYKKRVAVIDVQTHHGPPHYAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL
Sbjct: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPG+EHCISSNE
Sbjct: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGVEHCISSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK
Sbjct: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG
Sbjct: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT
Sbjct: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIXXXXXXXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLI YMSSFTPLMHNISGSKYKKFVAKIVTNHS
Sbjct: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYY+K
Sbjct: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYLK 480
Query: 481 GEKMEKLPDSNL 492
GEKME LP+S+L
Sbjct: 481 GEKMETLPESSL 492
>gi|136619|sp|P13110|TYTR_TRYCO Trypanothione reductase (TR) (N(1),N(8)-bis(glutathionyl)spermidine
reductase)
gi|162311|gb|AAA30258.1| trypanothione reductase
Length = 492
Score = 865 bits (2234), Expect = 0.0, Method: Composition-based stats.
Identities = 411/492 (83%), Positives = 445/492 (90%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSKAFDLV+IGAGSGGLEAGWNAATLY KRVAVVDVQT HGPPF+AALGGTCVNVGCVPK
Sbjct: 1 MSKAFDLVIIGAGSGGLEAGWNAATLYKKRVAVVDVQTVHGPPFFAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMD LRESAGFGWEFD S++KANWK LIAAKN AVLDINKSYE MF DTEGL
Sbjct: 61 KLMVTGAQYMDQLRESAGFGWEFDASTIKANWKTLIAAKNAAVLDINKSYEDMFKDTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWG+LE KNVV VRE ADPKS VKERLQA+HI++ATGSWPQM IPGIEHCISSNE
Sbjct: 121 EFFLGWGALEQKNVVTVREGADPKSKVKERLQAEHIIIATGSWPQMLKIPGIEHCISSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL EPPRRVLTVGGGFISVEFAGIFNAYKP GGKVTLCYRNN ILRGFD T+R+E+TK
Sbjct: 181 AFYLEEPPRRVLTVGGGFISVEFAGIFNAYKPVGGKVTLCYRNNPILRGFDYTLRQELTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI+IMTNENP+K+ LN DGSKHVTFESGKTLDVDVVMMAIGR+PRT LQL VG
Sbjct: 241 QLVANGIDIMTNENPSKIELNPDGSKHVTFESGKTLDVDVVMMAIGRLPRTGYLQLQTVG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V LT KG +QVDEFSRTNVPNIYAIGD+T R+MLTPVAINEGA++VDT+FG+KPRKTDHT
Sbjct: 301 VNLTDKGAIQVDEFSRTNVPNIYAIGDVTGRIMLTPVAINEGASVVDTIFGSKPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIXXXXXXXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGL Y+S FTPLMHNISGSKYKKFVAKI+T+H
Sbjct: 361 RVASAVFSIPPIGTCGLTEEEAAKSFEKVAVYLSCFTPLMHNISGSKYKKFVAKIITDHG 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTV+GVHLLGD +PEIIQAVG+C++LNAKISDFYNTIGVHPTSAEELCSMRTPS+YY+K
Sbjct: 421 DGTVVGVHLLGDSSPEIIQAVGICMKLNAKISDFYNTIGVHPTSAEELCSMRTPSHYYIK 480
Query: 481 GEKMEKLPDSNL 492
GEKME LPDS+L
Sbjct: 481 GEKMETLPDSSL 492
>gi|640319|pdb|1NDA|A Chain A, The Structure Of Trypanosoma Cruzi Trypanothione Reductase
In The Oxidized And Nadph Reduced State
gi|640320|pdb|1NDA|B Chain B, The Structure Of Trypanosoma Cruzi Trypanothione Reductase
In The Oxidized And Nadph Reduced State
gi|157879376|pdb|1NDA|C Chain C, The Structure Of Trypanosoma Cruzi Trypanothione Reductase
In The Oxidized And Nadph Reduced State
gi|157879377|pdb|1NDA|D Chain D, The Structure Of Trypanosoma Cruzi Trypanothione Reductase
In The Oxidized And Nadph Reduced State
Length = 491
Score = 836 bits (2159), Expect = 0.0, Method: Composition-based stats.
Identities = 400/492 (81%), Positives = 436/492 (88%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPK
Sbjct: 1 MSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYM+HLRESAGFGWEFD ++++A WKKLIA K+EAVL+INKSYE MF DTEGL
Sbjct: 61 KLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWGSLESKNVV VRE+ADP SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNE
Sbjct: 121 EFFLGWGSLESKNVVNVRESADPASAVKERLETENILLASGSWPHMPNIPGIEHCISSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TK
Sbjct: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N G
Sbjct: 241 QLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V + GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHT
Sbjct: 301 V-MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHT 359
Query: 361 RVASAVFSIPPIGTCGLIXXXXXXXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLI Y+SSFTPLMHNISGSKYK FVAKI+TNHS
Sbjct: 360 RVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHS 419
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGD APEIIQ VG+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 420 DGTVLGVHLLGDNAPEIIQGVGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 479
Query: 481 GEKMEKLPDSNL 492
GEKMEK +++L
Sbjct: 480 GEKMEKPSEASL 491
>gi|136620|sp|P28593|TYTR_TRYCR Trypanothione reductase (TR) (N(1),N(8)-bis(glutathionyl)spermidine
reductase)
gi|162317|gb|AAA63547.1| trypanothione reductase
Length = 492
Score = 836 bits (2159), Expect = 0.0, Method: Composition-based stats.
Identities = 400/492 (81%), Positives = 436/492 (88%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPK
Sbjct: 2 MSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPK 61
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYM+HLRESAGFGWEFD ++++A WKKLIA K+EAVL+INKSYE MF DTEGL
Sbjct: 62 KLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGL 121
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWGSLESKNVV VRE+ADP SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNE
Sbjct: 122 EFFLGWGSLESKNVVNVRESADPASAVKERLETENILLASGSWPHMPNIPGIEHCISSNE 181
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TK
Sbjct: 182 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 241
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N G
Sbjct: 242 QLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAG 301
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V + GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHT
Sbjct: 302 V-MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIXXXXXXXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLI Y+SSFTPLMHNISGSKYK FVAKI+TNHS
Sbjct: 361 RVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHS 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGD APEIIQ VG+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 421 DGTVLGVHLLGDNAPEIIQGVGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
Query: 481 GEKMEKLPDSNL 492
GEKMEK +++L
Sbjct: 481 GEKMEKPSEASL 492
>gi|71405339|ref|XP_805296.1| trypanothione reductase [Trypanosoma cruzi strain CL Brener]
gi|70868650|gb|EAN83445.1| trypanothione reductase, putative [Trypanosoma cruzi]
Length = 492
Score = 833 bits (2151), Expect = 0.0, Method: Composition-based stats.
Identities = 397/492 (80%), Positives = 435/492 (88%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPK
Sbjct: 2 MSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPK 61
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYM+HLRESAGFGWEFD ++++A WKKLIA K+EAVL+INKSYE MF DTEGL
Sbjct: 62 KLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGL 121
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWGSLESKNVV VRE+ADP SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNE
Sbjct: 122 EFFLGWGSLESKNVVNVRESADPASAVKERLETENILLASGSWPHMPNIPGIEHCISSNE 181
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TK
Sbjct: 182 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 241
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N G
Sbjct: 242 QLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAG 301
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V + GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDT+FG PRKTDHT
Sbjct: 302 V-MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTIFGTTPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIXXXXXXXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLI Y+SSFTPLMH +SGSKYK FVAKI+TNHS
Sbjct: 361 RVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHS 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGD APEIIQ VG+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 421 DGTVLGVHLLGDNAPEIIQGVGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
Query: 481 GEKMEKLPDSNL 492
GEKMEK +++L
Sbjct: 481 GEKMEKPSEASL 492
>gi|49258301|pdb|1GXF|A Chain A, Crystal Structure Of Trypanosoma Cruzi Trypanothione
Reductase In Complex With The Inhibitor Quinacrine
Mustard
gi|49258302|pdb|1GXF|B Chain B, Crystal Structure Of Trypanosoma Cruzi Trypanothione
Reductase In Complex With The Inhibitor Quinacrine
Mustard
gi|624038|emb|CAA78360.1| trypanothione reductase [Trypanosoma cruzi]
Length = 492
Score = 832 bits (2150), Expect = 0.0, Method: Composition-based stats.
Identities = 396/492 (80%), Positives = 434/492 (88%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPK
Sbjct: 2 MSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPK 61
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYM+HLRESAGFGWEFD ++++A WK LIA K+EAVL+INKSY+ MF DTEGL
Sbjct: 62 KLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTEGL 121
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWGSLESKNVV VRE+ADP SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNE
Sbjct: 122 EFFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNE 181
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TK
Sbjct: 182 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 241
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N G
Sbjct: 242 QLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAG 301
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V + GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHT
Sbjct: 302 V-MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIXXXXXXXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLI Y+SSFTPLMH +SGSKYK FVAKI+TNHS
Sbjct: 361 RVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHS 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGD APEIIQ +G+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 421 DGTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
Query: 481 GEKMEKLPDSNL 492
GEKMEK +++L
Sbjct: 481 GEKMEKPSEASL 492
>gi|6573510|pdb|1BZL|A Chain A, Crystal Structure Of Trypanosoma Cruzi Trypanothione
Reductase In Complex With Trypanothione, And The
Structure- Based Discovery Of New Natural Product
Inhibitors
gi|6573511|pdb|1BZL|B Chain B, Crystal Structure Of Trypanosoma Cruzi Trypanothione
Reductase In Complex With Trypanothione, And The
Structure- Based Discovery Of New Natural Product
Inhibitors
Length = 486
Score = 831 bits (2146), Expect = 0.0, Method: Composition-based stats.
Identities = 395/486 (81%), Positives = 430/486 (88%), Gaps = 1/486 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPK
Sbjct: 1 MSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYM+HLRESAGFGWEFD ++++A WK LIA K+EAVL+INKSY+ MF DTEGL
Sbjct: 61 KLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWGSLESKNVV VRE+ADP SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNE
Sbjct: 121 EFFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TK
Sbjct: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N G
Sbjct: 241 QLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V + GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHT
Sbjct: 301 V-MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHT 359
Query: 361 RVASAVFSIPPIGTCGLIXXXXXXXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLI Y+SSFTPLMH +SGSKYK FVAKI+TNHS
Sbjct: 360 RVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHS 419
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGD APEIIQ +G+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 420 DGTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 479
Query: 481 GEKMEK 486
GEKMEK
Sbjct: 480 GEKMEK 485
>gi|2554795|pdb|1AOG|A Chain A, Trypanosoma Cruzi Trypanothione Reductase (Oxidized Form)
gi|2554796|pdb|1AOG|B Chain B, Trypanosoma Cruzi Trypanothione Reductase (Oxidized Form)
Length = 485
Score = 829 bits (2141), Expect = 0.0, Method: Composition-based stats.
Identities = 394/485 (81%), Positives = 429/485 (88%), Gaps = 1/485 (0%)
Query: 2 SKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKK 61
SK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKK
Sbjct: 1 SKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKK 60
Query: 62 LMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLD 121
LMVTGAQYM+HLRESAGFGWEFD ++++A WK LIA K+EAVL+INKSY+ MF DTEGL+
Sbjct: 61 LMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTEGLE 120
Query: 122 FFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEA 181
FFLGWGSLESKNVV VRE+ADP SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEA
Sbjct: 121 FFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEA 180
Query: 182 FYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQ 241
FYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQ
Sbjct: 181 FYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQ 240
Query: 242 LTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGV 301
LTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N GV
Sbjct: 241 LTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV 300
Query: 302 KLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTR 361
+ GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTR
Sbjct: 301 -MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTR 359
Query: 362 VASAVFSIPPIGTCGLIXXXXXXXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSD 421
VASAVFSIPPIGTCGLI Y+SSFTPLMH +SGSKYK FVAKI+TNHSD
Sbjct: 360 VASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSD 419
Query: 422 GTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKG 481
GTVLGVHLLGD APEIIQ +G+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKG
Sbjct: 420 GTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKG 479
Query: 482 EKMEK 486
EKMEK
Sbjct: 480 EKMEK 484
>gi|552297|gb|AAB59211.1| trypanothione reductase [Trypanosoma cruzi]
Length = 453
Score = 767 bits (1981), Expect = 0.0, Method: Composition-based stats.
Identities = 365/454 (80%), Positives = 400/454 (88%), Gaps = 1/454 (0%)
Query: 8 VVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGA 67
VVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGA
Sbjct: 1 VVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGA 60
Query: 68 QYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWG 127
QYM+HLRESAGFGWEFD ++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWG
Sbjct: 61 QYMEHLRESAGFGWEFDRTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWG 120
Query: 128 SLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEP 187
SLESKNVV VRE+ADP SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEP
Sbjct: 121 SLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEP 180
Query: 188 PRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGI 247
PRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI
Sbjct: 181 PRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGI 240
Query: 248 EIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKG 307
+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + G
Sbjct: 241 QILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNG 299
Query: 308 GVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVF 367
GVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVF
Sbjct: 300 GVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVF 359
Query: 368 SIPPIGTCGLIXXXXXXXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGV 427
SIPPIGTCGLI Y+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGV
Sbjct: 360 SIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGV 419
Query: 428 HLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVH 461
HLLGD APEIIQ +G+CL+LNAKISDFYNTIGVH
Sbjct: 420 HLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVH 453
>gi|14600050|gb|AAK71224.1|AF359006_1 trypanothione reductase [Trypanosoma cruzi marinkellei]
gi|14600052|gb|AAK71225.1|AF359007_1 trypanothione reductase [Trypanosoma cruzi marinkellei]
Length = 430
Score = 734 bits (1896), Expect = 0.0, Method: Composition-based stats.
Identities = 348/431 (80%), Positives = 383/431 (88%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIAAK+EAVL+INKSYE MF DTEGL+FF+GWGSLESKNVV VRE+ADP
Sbjct: 61 RTTIRAEWKKLIAAKDEAVLNINKSYEEMFRDTEGLEFFMGWGSLESKNVVNVRESADPS 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HIL+A+GSWP MP IPGIEHC+SSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILVASGSWPHMPNIPGIEHCVSSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VM+AIGR PRTNDLQL N GV +T G VQVDE+SRTNVPNIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMIAIGRSPRTNDLQLQNAGV-ITKNGAVQVDEYSRTNVPNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXXX 384
IGD+T+R+MLTPVAINEGAALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 IGDVTNRVMLTPVAINEGAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 XXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
Y+SSFTPLMHNISGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VGVC
Sbjct: 360 RYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGVC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gi|14600010|gb|AAK71204.1|AF358986_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 727 bits (1877), Expect = 0.0, Method: Composition-based stats.
Identities = 345/431 (80%), Positives = 378/431 (87%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXXX 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 XXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
Y+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gi|14600014|gb|AAK71206.1|AF358988_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600016|gb|AAK71207.1|AF358989_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600020|gb|AAK71209.1|AF358991_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600030|gb|AAK71214.1|AF358996_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600034|gb|AAK71216.1|AF358998_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600038|gb|AAK71218.1|AF359000_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600042|gb|AAK71220.1|AF359002_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600046|gb|AAK71222.1|AF359004_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 727 bits (1876), Expect = 0.0, Method: Composition-based stats.
Identities = 344/431 (79%), Positives = 378/431 (87%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXXX 384
IGD+T+R+MLTPVAINE AALVDT+FG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTIFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 XXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
Y+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gi|14600022|gb|AAK71210.1|AF358992_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600024|gb|AAK71211.1|AF358993_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600026|gb|AAK71212.1|AF358994_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600028|gb|AAK71213.1|AF358995_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600032|gb|AAK71215.1|AF358997_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600036|gb|AAK71217.1|AF358999_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600040|gb|AAK71219.1|AF359001_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600044|gb|AAK71221.1|AF359003_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600048|gb|AAK71223.1|AF359005_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 727 bits (1876), Expect = 0.0, Method: Composition-based stats.
Identities = 346/431 (80%), Positives = 379/431 (87%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETENILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXXX 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 XXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
Y+SSFTPLMHNISGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+C
Sbjct: 360 RYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gi|14600000|gb|AAK71199.1|AF358981_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600012|gb|AAK71205.1|AF358987_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 725 bits (1872), Expect = 0.0, Method: Composition-based stats.
Identities = 343/431 (79%), Positives = 378/431 (87%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKDGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXXX 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 XXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
Y+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gi|14599976|gb|AAK71187.1|AF358969_1 trypanothione reductase [Trypanosoma cruzi]
gi|14599978|gb|AAK71188.1|AF358970_1 trypanothione reductase [Trypanosoma cruzi]
gi|14599982|gb|AAK71190.1|AF358972_1 trypanothione reductase [Trypanosoma cruzi]
gi|14599984|gb|AAK71191.1|AF358973_1 trypanothione reductase [Trypanosoma cruzi]
gi|14599986|gb|AAK71192.1|AF358974_1 trypanothione reductase [Trypanosoma cruzi]
gi|14599988|gb|AAK71193.1|AF358975_1 trypanothione reductase [Trypanosoma cruzi]
gi|14599990|gb|AAK71194.1|AF358976_1 trypanothione reductase [Trypanosoma cruzi]
gi|14599992|gb|AAK71195.1|AF358977_1 trypanothione reductase [Trypanosoma cruzi]
gi|14599994|gb|AAK71196.1|AF358978_1 trypanothione reductase [Trypanosoma cruzi]
gi|14599996|gb|AAK71197.1|AF358979_1 trypanothione reductase [Trypanosoma cruzi]
gi|14599998|gb|AAK71198.1|AF358980_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600002|gb|AAK71200.1|AF358982_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600004|gb|AAK71201.1|AF358983_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600006|gb|AAK71202.1|AF358984_1 trypanothione reductase [Trypanosoma cruzi]
gi|14600008|gb|AAK71203.1|AF358985_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 725 bits (1872), Expect = 0.0, Method: Composition-based stats.
Identities = 343/431 (79%), Positives = 378/431 (87%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXXX 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 XXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
Y+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gi|61207374|gb|AAX40409.1| trypanothione reductase [Trypanosoma cruzi]
gi|61207378|gb|AAX40411.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 725 bits (1872), Expect = 0.0, Method: Composition-based stats.
Identities = 344/431 (79%), Positives = 378/431 (87%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXX 383
AIGD+T+R+MLTPVAINE AALVDT+FG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTIFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 XXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
Y+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+
Sbjct: 360 KRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gi|61207342|gb|AAX40393.1| trypanothione reductase [Trypanosoma cruzi]
gi|61207344|gb|AAX40394.1| trypanothione reductase [Trypanosoma cruzi]
gi|61207346|gb|AAX40395.1| trypanothione reductase [Trypanosoma cruzi]
gi|61207348|gb|AAX40396.1| trypanothione reductase [Trypanosoma cruzi]
gi|61207350|gb|AAX40397.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 725 bits (1872), Expect = 0.0, Method: Composition-based stats.
Identities = 346/431 (80%), Positives = 379/431 (87%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETENILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXX 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 XXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
Y+SSFTPLMHNISGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+
Sbjct: 360 KRYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gi|61207372|gb|AAX40408.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 725 bits (1872), Expect = 0.0, Method: Composition-based stats.
Identities = 344/431 (79%), Positives = 378/431 (87%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKEMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXX 383
AIGD+T+R+MLTPVAINE AALVDT+FG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTIFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 XXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
Y+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+
Sbjct: 360 KRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gi|14600018|gb|AAK71208.1|AF358990_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 724 bits (1870), Expect = 0.0, Method: Composition-based stats.
Identities = 343/431 (79%), Positives = 377/431 (87%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTAN I+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANSIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXXX 384
IGD+T+R+MLTPVAINE AALVDT+FG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTIFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 XXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
Y+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gi|61207354|gb|AAX40399.1| trypanothione reductase [Trypanosoma cruzi]
gi|61207358|gb|AAX40401.1| trypanothione reductase [Trypanosoma cruzi]
gi|61207362|gb|AAX40403.1| trypanothione reductase [Trypanosoma cruzi]
gi|61207364|gb|AAX40404.1| trypanothione reductase [Trypanosoma cruzi]
gi|61207366|gb|AAX40405.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 724 bits (1868), Expect = 0.0, Method: Composition-based stats.
Identities = 343/431 (79%), Positives = 378/431 (87%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXX 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 XXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
Y+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+
Sbjct: 360 KRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gi|14599980|gb|AAK71189.1|AF358971_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 724 bits (1868), Expect = 0.0, Method: Composition-based stats.
Identities = 342/431 (79%), Positives = 378/431 (87%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK ++ D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMEFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXXX 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 XXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
Y+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gi|14600054|gb|AAK71226.1|AF359008_1 trypanothione reductase [Trypanosoma vespertilionis]
Length = 430
Score = 724 bits (1868), Expect = 0.0, Method: Composition-based stats.
Identities = 343/431 (79%), Positives = 378/431 (87%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA+K+EAVL+INKSYE MF DTEGL+FF+GWGSLESKNVV VRE+A+P
Sbjct: 61 RTTLRAEWKKLIASKDEAVLNINKSYEEMFRDTEGLEFFMGWGSLESKNVVNVRESAEPD 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T +NPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTVREELTKQLTANGIQILTKDNPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GVQVDE+SRTNVPNIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNSGVQVDEYSRTNVPNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXXX 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 XXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
Y+SSFTPLMH ISGS YK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VGVC
Sbjct: 360 RYEVVAVYLSSFTPLMHKISGSNYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGVC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gi|61207360|gb|AAX40402.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 722 bits (1864), Expect = 0.0, Method: Composition-based stats.
Identities = 342/431 (79%), Positives = 377/431 (87%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SR NV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRMNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXX 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 XXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
Y+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+
Sbjct: 360 KRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gi|61207376|gb|AAX40410.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 722 bits (1863), Expect = 0.0, Method: Composition-based stats.
Identities = 345/431 (80%), Positives = 378/431 (87%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ ++ILLA+GSWP MP I GIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETENILLASGSWPHMPNILGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIXXXXX 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLI
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 XXXXXXXXYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
Y+SSFTPLMHNISGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+
Sbjct: 360 KRYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430