BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= ENSG00000133835__[Homo_sapiens]
(736 letters)
Database: nr.pal
6,348,806 sequences; 2,166,943,470 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504505|ref|NP_000405.1| hydroxysteroid (17-beta) dehydr... 1380 0.0
gi|114601365|ref|XP_517892.2| PREDICTED: hydroxysteroid (17... 1353 0.0
gi|109078303|ref|XP_001087837.1| PREDICTED: hydroxysteroid ... 1332 0.0
gi|162287198|ref|NP_077368.2| hydroxysteroid (17-beta) dehy... 1242 0.0
gi|74179905|dbj|BAE36514.1| unnamed protein product [Mus mu... 1238 0.0
gi|31982273|ref|NP_032318.2| hydroxysteroid (17-beta) dehyd... 1237 0.0
gi|1213008|emb|CAA62015.1| 17beta-hydroxysteroid dehydrogen... 1234 0.0
gi|1592545|gb|AAB09724.1| peroxisomal multifunctional enzym... 1234 0.0
gi|74180924|dbj|BAE27744.1| unnamed protein product [Mus mu... 1234 0.0
gi|48734844|gb|AAH72472.1| Hsd17b4 protein [Rattus norvegicus] 1231 0.0
gi|73970527|ref|XP_531860.2| PREDICTED: similar to Peroxiso... 1230 0.0
gi|1620451|emb|CAA64427.1| multifunctional protein 2 [Rattu... 1224 0.0
gi|73970533|ref|XP_859341.1| PREDICTED: similar to Peroxiso... 1224 0.0
gi|73970531|ref|XP_859306.1| PREDICTED: similar to Peroxiso... 1219 0.0
gi|148677987|gb|EDL09934.1| hydroxysteroid (17-beta) dehydr... 1214 0.0
gi|113911805|gb|AAI22585.1| Hydroxysteroid (17-beta) dehydr... 1214 0.0
gi|126352659|ref|NP_001075370.1| 17 beta-hydroxysteroid deh... 1214 0.0
gi|56119094|ref|NP_001007810.1| hydroxysteroid (17-beta) de... 1208 0.0
gi|3005897|emb|CAA73945.1| mutifunctional protein2 [Cavia p... 1200 0.0
gi|149064233|gb|EDM14436.1| hydroxysteroid (17-beta) dehydr... 1184 0.0
gi|47523670|ref|NP_999471.1| hydroxysteroid (17-beta) dehyd... 1179 0.0
gi|126333832|ref|XP_001378211.1| PREDICTED: similar to 17be... 1152 0.0
gi|119569295|gb|EAW48910.1| hydroxysteroid (17-beta) dehydr... 1146 0.0
gi|109078307|ref|XP_001088200.1| PREDICTED: hydroxysteroid ... 1114 0.0
gi|73970529|ref|XP_859266.1| PREDICTED: similar to Peroxiso... 1036 0.0
gi|149412925|ref|XP_001512505.1| PREDICTED: similar to 17be... 1022 0.0
gi|45384406|ref|NP_990274.1| hydroxysteroid (17-beta) dehyd... 1021 0.0
gi|73853814|ref|NP_001027490.1| hypothetical protein LOC613... 1020 0.0
gi|148236841|ref|NP_001086063.1| MGC81885 protein [Xenopus ... 1011 0.0
gi|154425487|dbj|BAF74749.1| hydroxysteroid (17-beta) dehyd... 994 0.0
gi|149064232|gb|EDM14435.1| hydroxysteroid (17-beta) dehydr... 967 0.0
gi|42409521|ref|NP_956430.1| hydroxysteroid (17-beta) dehyd... 947 0.0
gi|13491722|gb|AAK27967.1|AF241285_1 17-beta-hydroxysteroid... 946 0.0
gi|42406324|gb|AAH65945.1| Hsd17b4 protein [Danio rerio] 942 0.0
gi|62087444|dbj|BAD92169.1| hydroxysteroid (17-beta) dehydr... 875 0.0
gi|47227603|emb|CAG09600.1| unnamed protein product [Tetrao... 863 0.0
gi|52782233|dbj|BAD51963.1| 17-beta hydroxysteroid dehydrog... 843 0.0
gi|109078305|ref|XP_001087962.1| PREDICTED: hydroxysteroid ... 813 0.0
gi|156359767|ref|XP_001624936.1| predicted protein [Nematos... 786 0.0
gi|91085817|ref|XP_974784.1| PREDICTED: similar to Peroxiso... 674 0.0
gi|156554853|ref|XP_001606624.1| PREDICTED: similar to estr... 671 0.0
gi|157114880|ref|XP_001652466.1| estradiol 17 beta-dehydrog... 667 0.0
gi|170030366|ref|XP_001843060.1| peroxisomal multifunctiona... 664 0.0
gi|66534671|ref|XP_393475.2| PREDICTED: similar to Peroxiso... 646 0.0
gi|158293426|ref|XP_314766.4| AGAP008667-PA [Anopheles gamb... 643 0.0
gi|5869811|emb|CAB55552.1| Fox2 protein [Glomus mosseae] 639 0.0
gi|167518323|ref|XP_001743502.1| predicted protein [Monosig... 631 e-179
gi|66361418|pdb|1ZBQ|A Chain A, Crystal Structure Of Human ... 571 e-161
gi|61679854|pdb|1S9C|A Chain A, Crystal Structure Analysis ... 569 e-160
gi|18859837|ref|NP_573109.1| CG3415 CG3415-PA [Drosophila m... 559 e-157
gi|90081162|dbj|BAE90061.1| unnamed protein product [Macaca... 548 e-154
gi|125982251|ref|XP_001355058.1| GA17436-PA [Drosophila pse... 541 e-152
gi|28373303|pdb|1GZ6|A Chain A, (3r)-Hydroxyacyl-Coa Dehydr... 516 e-144
gi|148677986|gb|EDL09933.1| hydroxysteroid (17-beta) dehydr... 510 e-142
gi|93279090|pdb|2CDH|S Chain S, Architecture Of The Thermom... 491 e-136
gi|39975851|ref|XP_369316.1| peroxisomal hydratase-dehydrog... 474 e-131
gi|1090092|prf||2018258A 17beta-estradiol dehydrogenase 462 e-128
gi|154272155|ref|XP_001536930.1| hypothetical protein HCAG_... 462 e-128
gi|85105803|ref|XP_962039.1| peroxisomal hydratase-dehydrog... 461 e-128
gi|119895202|ref|XP_001253030.1| PREDICTED: similar to Mult... 461 e-127
gi|116194468|ref|XP_001223046.1| peroxisomal hydratase-dehy... 459 e-127
gi|70982097|ref|XP_746577.1| peroxisomal multifunctional be... 451 e-125
gi|46136255|ref|XP_389819.1| FOX2_NEUCR Peroxisomal hydrata... 451 e-125
gi|119487120|ref|XP_001262415.1| peroxisomal multifunctiona... 451 e-125
gi|169620898|ref|XP_001803860.1| hypothetical protein SNOG_... 450 e-124
gi|50553140|ref|XP_503980.1| hypothetical protein [Yarrowia... 449 e-124
gi|145248778|ref|XP_001400728.1| hypothetical protein An14g... 448 e-124
gi|119180044|ref|XP_001241529.1| hypothetical protein CIMG_... 443 e-122
gi|71003233|ref|XP_756297.1| hypothetical protein UM00150.1... 440 e-121
gi|154290505|ref|XP_001545846.1| hypothetical protein BC1G_... 438 e-121
gi|156045515|ref|XP_001589313.1| hypothetical protein SS1G_... 437 e-120
gi|169783026|ref|XP_001825975.1| [Aspergillus oryzae] >gi|8... 437 e-120
gi|121714445|ref|XP_001274833.1| peroxisomal multifunctiona... 432 e-119
gi|67541895|ref|XP_664715.1| hypothetical protein AN7111.2 ... 432 e-119
gi|115387787|ref|XP_001211399.1| acetoacetyl-CoA reductase ... 431 e-118
gi|58268866|ref|XP_571589.1| peroxisomal hydratase-dehydrog... 430 e-118
gi|170098915|ref|XP_001880676.1| multifunctional beta-oxida... 419 e-115
gi|164657291|ref|XP_001729772.1| hypothetical protein MGL_3... 406 e-111
gi|115361554|gb|ABI95866.1| 17-beta-hydroxysteroid dehydrog... 392 e-107
gi|126132968|ref|XP_001383009.1| hypothetical protein PICST... 374 e-101
gi|115629117|ref|XP_786662.2| PREDICTED: similar to 17-beta... 369 e-100
gi|156837464|ref|XP_001642757.1| hypothetical protein Kpol_... 367 1e-99
gi|50407352|ref|XP_456704.1| hypothetical protein DEHA0A087... 367 2e-99
gi|146416347|ref|XP_001484143.1| hypothetical protein PGUG_... 365 5e-99
gi|50309137|ref|XP_454574.1| unnamed protein product [Kluyv... 361 1e-97
gi|9858763|gb|AAG01113.1| 17-beta-hydroxysteroid dehydrogen... 361 1e-97
gi|68492311|ref|XP_710072.1| peroxisomal hydratase-dehydrog... 360 2e-97
gi|149245821|ref|XP_001527383.1| peroxisomal hydratase-dehy... 357 3e-96
gi|1708156|sp|P22414|FOX2_CANTR Peroxisomal hydratase-dehyd... 353 3e-95
gi|695398|gb|AAA62847.1| hydratase-dehydrogenase-epimerase 349 3e-94
gi|6322861|ref|NP_012934.1| Multifunctional enzyme of the p... 344 1e-92
gi|151941554|gb|EDN59917.1| multifunctional beta-oxidation ... 343 2e-92
gi|50292863|ref|XP_448864.1| unnamed protein product [Candi... 338 8e-91
gi|66802762|ref|XP_635235.1| hypothetical protein DDB_02016... 335 6e-90
gi|45201036|ref|NP_986606.1| AGL060Wp [Ashbya gossypii ATCC... 334 2e-89
gi|85373026|ref|YP_457088.1| probable short-chain dehydroge... 330 3e-88
gi|146281485|ref|YP_001171638.1| probable short-chain dehyd... 323 2e-86
gi|146308297|ref|YP_001188762.1| short-chain dehydrogenase/... 323 3e-86
gi|77457130|ref|YP_346635.1| Short-chain dehydrogenase/redu... 323 4e-86
gi|70728343|ref|YP_258092.1| oxidoreductase, short chain de... 322 6e-86
>gi|4504505|ref|NP_000405.1| hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
gi|1706396|sp|P51659|DHB4_HUMAN Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) (D-3-hydroxyacyl-CoA dehydratase)
(3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase) (3-hydroxyacyl-CoA dehydrogenase)
gi|1050517|emb|CAA60643.1| 17beta-hydroxysteroid dehydrogenase [Homo sapiens]
gi|4165049|gb|AAD08652.1| 17-beta-hydroxysteroid dehydrogenase IV [Homo sapiens]
gi|13111861|gb|AAH03098.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
gi|119569296|gb|EAW48911.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Homo
sapiens]
gi|123981926|gb|ABM82792.1| hydroxysteroid (17-beta) dehydrogenase 4 [synthetic construct]
gi|123996759|gb|ABM85981.1| hydroxysteroid (17-beta) dehydrogenase 4 [synthetic construct]
Length = 736
Score = 1380 bits (3572), Expect = 0.0, Method: Composition-based stats.
Identities = 684/736 (92%), Positives = 684/736 (92%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFD ERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEGGV GAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
Sbjct: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
Sbjct: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQ KRTSDKVKV
Sbjct: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI
Sbjct: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
Sbjct: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 721 MLSQKLQMILKDYAKL 736
>gi|114601365|ref|XP_517892.2| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 [Pan
troglodytes]
Length = 712
Score = 1353 bits (3501), Expect = 0.0, Method: Composition-based stats.
Identities = 665/702 (94%), Positives = 667/702 (95%)
Query: 35 LVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRID 94
V +NDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRID
Sbjct: 11 FVSMNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRID 70
Query: 95 VVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASG 154
VVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASG
Sbjct: 71 VVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASG 130
Query: 155 IYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALK 214
IYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALK
Sbjct: 131 IYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALK 190
Query: 215 PEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWK 274
PEYVAPLVLWLCH+SCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWK
Sbjct: 191 PEYVAPLVLWLCHDSCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWK 250
Query: 275 KICDFENASKPQSIQESTGSIIEVLSKIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPP 334
KICDFENASKPQSIQESTGSIIEVLSKIDSEGGV GAIGQKLPP
Sbjct: 251 KICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPP 310
Query: 335 FSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI 394
FSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI
Sbjct: 311 FSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI 370
Query: 395 PGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELI 454
PGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELI
Sbjct: 371 PGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELI 430
Query: 455 CHNQXXXXXXXXXXXXXKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPL 514
CHNQ KRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPL
Sbjct: 431 CHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPL 490
Query: 515 HIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQ 574
HIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQ
Sbjct: 491 HIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQ 550
Query: 575 TEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRR 634
TEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTS TSAKTPSEG KLQST VFEEIGRR
Sbjct: 551 TEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSDTSAKTPSEGEKLQSTLVFEEIGRR 610
Query: 635 LKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDED 694
LKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDED
Sbjct: 611 LKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDED 670
Query: 695 FMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
FMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 671 FMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 712
>gi|109078303|ref|XP_001087837.1| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 isoform 1
[Macaca mulatta]
Length = 734
Score = 1332 bits (3448), Expect = 0.0, Method: Composition-based stats.
Identities = 665/736 (90%), Positives = 674/736 (91%), Gaps = 2/736 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFD ERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVA+YDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 61 EIRRRGGKAVASYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG V GAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
Sbjct: 301 KIDSEG-VSANHTSHATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGSSDFSCLPTFGVIIGQKS+MGGGLAEIPGLSINFAKV+ GE ++ KPL R
Sbjct: 360 LKFVYEGSSDFSCLPTFGVIIGQKSLMGGGLAEIPGLSINFAKVI-GEPSMKAEKPLKRV 418
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQ KRTSDKVKV
Sbjct: 419 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 478
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 479 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 538
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
ARR+LQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 539 ARRILQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 598
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDLAPTS TSAKTPSEGGKLQST VFEEIGRRLKD+GPEVVKKVNAVFEWHITKGGNI
Sbjct: 599 AYVDLAPTSDTSAKTPSEGGKLQSTLVFEEIGRRLKDVGPEVVKKVNAVFEWHITKGGNI 658
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
Sbjct: 659 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 718
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 719 MLSQKLQMILKDYAKL 734
>gi|162287198|ref|NP_077368.2| hydroxysteroid (17-beta) dehydrogenase 4 [Rattus norvegicus]
gi|2492741|sp|P97852|DHB4_RAT Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) (D-3-hydroxyacyl-CoA dehydratase)
(3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase) (3-hydroxyacyl-CoA dehydrogenase)
gi|1881831|gb|AAB49519.1| 17 beta-hydroxysteroid dehydrogenase type IV; HSD IV [Rattus sp.]
Length = 735
Score = 1242 bits (3214), Expect = 0.0, Method: Composition-based stats.
Identities = 602/736 (81%), Positives = 646/736 (87%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFD ERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG + G +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQ KRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>gi|74179905|dbj|BAE36514.1| unnamed protein product [Mus musculus]
Length = 735
Score = 1238 bits (3204), Expect = 0.0, Method: Composition-based stats.
Identities = 593/736 (80%), Positives = 642/736 (87%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFD ERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG + GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQ KRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTHTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>gi|31982273|ref|NP_032318.2| hydroxysteroid (17-beta) dehydrogenase 4 [Mus musculus]
gi|94730372|sp|P51660|DHB4_MOUSE Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) (D-3-hydroxyacyl-CoA dehydratase)
(3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase) (3-hydroxyacyl-CoA dehydrogenase)
gi|12836373|dbj|BAB23627.1| unnamed protein product [Mus musculus]
gi|18380947|gb|AAH22175.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Mus musculus]
gi|26353374|dbj|BAC40317.1| unnamed protein product [Mus musculus]
gi|74139444|dbj|BAE40862.1| unnamed protein product [Mus musculus]
gi|74177890|dbj|BAE39029.1| unnamed protein product [Mus musculus]
gi|74188898|dbj|BAE39222.1| unnamed protein product [Mus musculus]
gi|148677989|gb|EDL09936.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_d [Mus
musculus]
Length = 735
Score = 1237 bits (3201), Expect = 0.0, Method: Composition-based stats.
Identities = 593/736 (80%), Positives = 643/736 (87%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFD ERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG + GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQ KRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>gi|1213008|emb|CAA62015.1| 17beta-hydroxysteroid dehydrogenase IV [Mus musculus]
Length = 735
Score = 1234 bits (3194), Expect = 0.0, Method: Composition-based stats.
Identities = 592/736 (80%), Positives = 642/736 (87%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFD ERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGPGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG + GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPL R+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLLRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQ KRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>gi|1592545|gb|AAB09724.1| peroxisomal multifunctional enzyme type II
Length = 735
Score = 1234 bits (3192), Expect = 0.0, Method: Composition-based stats.
Identities = 599/736 (81%), Positives = 643/736 (87%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFD ERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDS E GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSGEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIY NFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYSNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG + G +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+ GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLTSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQ KRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPDRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>gi|74180924|dbj|BAE27744.1| unnamed protein product [Mus musculus]
Length = 735
Score = 1234 bits (3192), Expect = 0.0, Method: Composition-based stats.
Identities = 592/736 (80%), Positives = 642/736 (87%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFD ERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG + GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQ KRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSG WNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGGWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>gi|48734844|gb|AAH72472.1| Hsd17b4 protein [Rattus norvegicus]
Length = 751
Score = 1231 bits (3184), Expect = 0.0, Method: Composition-based stats.
Identities = 601/752 (79%), Positives = 645/752 (85%), Gaps = 17/752 (2%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFD ERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG + G +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQ KRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKW----------------TIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLD 704
AKW IDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+
Sbjct: 660 AAKWMELTISFSVSSLLPANAIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLN 719
Query: 705 PQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
PQ AFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 720 PQNAFFSGRLKARGNIMLSQKLQMILKDYAKL 751
>gi|73970527|ref|XP_531860.2| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 2 [Canis familiaris]
Length = 737
Score = 1230 bits (3182), Expect = 0.0, Method: Composition-based stats.
Identities = 597/737 (81%), Positives = 637/737 (86%), Gaps = 1/737 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAA-DKVV 59
M SPLRFD ERGA VVVNDLGGDFKG+GKGS AA DKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+ IDS+GGV GAIG K PPFS AYTELE IMYALGVGAS+K+PK
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPK 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
D+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPR
Sbjct: 361 DMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPR 420
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVK 479
AG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQ KRTSDKVK
Sbjct: 421 AGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVK 480
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGF
Sbjct: 481 ATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGF 540
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVIS
Sbjct: 541 SARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVIS 600
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
NAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGN
Sbjct: 601 NAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGN 660
Query: 660 IGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGN 719
I AKWTIDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKARGN
Sbjct: 661 IAAKWTIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKARGN 720
Query: 720 IMLSQKLQMILKDYAKL 736
IMLSQKLQMILKDYAKL
Sbjct: 721 IMLSQKLQMILKDYAKL 737
>gi|1620451|emb|CAA64427.1| multifunctional protein 2 [Rattus norvegicus]
Length = 734
Score = 1224 bits (3168), Expect = 0.0, Method: Composition-based stats.
Identities = 596/734 (81%), Positives = 641/734 (87%), Gaps = 1/734 (0%)
Query: 3 SPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
SPLRFD ERGALVVVNDLGGDFKGVGKGS AADKVVEEI
Sbjct: 2 SPLRFDGRVGLVTGAGGGLGRAYGLAFAERGALVVVNDLGGDFKGVGKGSSAADKVVEEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
RRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRD SF+RISDEDWDII RV
Sbjct: 62 RRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDPSFSRISDEDWDIIQRV 121
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
HLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L IEG
Sbjct: 122 HLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVIEG 181
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 242
RK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG
Sbjct: 182 RKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 241
Query: 243 WIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKI 302
WIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NAS+P+SIQESTG IIEVL KI
Sbjct: 242 WIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASEPKSIQESTGGIIEVLHKI 301
Query: 303 DSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLK 362
DSEG + G +G KLP FS +YTEL+ IMYALGVGAS+K+PKDLK
Sbjct: 302 DSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDLK 360
Query: 363 FIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGK 422
F+YEGS DFSCLPT GVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+G+
Sbjct: 361 FVYEGSPDFSCLPTIGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRSGE 420
Query: 423 LKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKVAV 482
LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQ KRTS+K+K AV
Sbjct: 421 LKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAAV 480
Query: 483 AIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSAR 542
A+P+RPPDAVL DTTS+NQAALYRLSGD NPLHIDP+FA +AGF+KPILHGLCTFGFSAR
Sbjct: 481 AVPSRPPDAVLRDTTSVNQAALYRLSGDSNPLHIDPSFAGIAGFEKPILHGLCTFGFSAR 540
Query: 543 RVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY 602
VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY
Sbjct: 541 HVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY 600
Query: 603 VDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGA 662
VDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+ A
Sbjct: 601 VDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVAA 660
Query: 663 KWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIML 722
KWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNIML
Sbjct: 661 KWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNIML 720
Query: 723 SQKLQMILKDYAKL 736
SQKLQMILKDYAKL
Sbjct: 721 SQKLQMILKDYAKL 734
>gi|73970533|ref|XP_859341.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 5 [Canis familiaris]
Length = 739
Score = 1224 bits (3168), Expect = 0.0, Method: Composition-based stats.
Identities = 597/739 (80%), Positives = 637/739 (86%), Gaps = 3/739 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAA-DKVV 59
M SPLRFD ERGA VVVNDLGGDFKG+GKGS AA DKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVXX--XXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
+ IDS+GGV GAIG K PPFS AYTELE IMYALGVGAS+K+
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEADMAGAIGHKFPPFSSAYTELETIMYALGVGASVKE 360
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPL 417
PKD+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPL
Sbjct: 361 PKDMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPL 420
Query: 418 PRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDK 477
PRAG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQ KRTSDK
Sbjct: 421 PRAGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDK 480
Query: 478 VKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTF 537
VK VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTF
Sbjct: 481 VKATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTF 540
Query: 538 GFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIV 597
GFSAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIV
Sbjct: 541 GFSARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIV 600
Query: 598 ISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKG 657
ISNAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKG
Sbjct: 601 ISNAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKG 660
Query: 658 GNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKAR 717
GNI AKWTIDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKAR
Sbjct: 661 GNIAAKWTIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKAR 720
Query: 718 GNIMLSQKLQMILKDYAKL 736
GNIMLSQKLQMILKDYAKL
Sbjct: 721 GNIMLSQKLQMILKDYAKL 739
>gi|73970531|ref|XP_859306.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 4 [Canis familiaris]
Length = 753
Score = 1219 bits (3154), Expect = 0.0, Method: Composition-based stats.
Identities = 596/753 (79%), Positives = 637/753 (84%), Gaps = 17/753 (2%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAA-DKVV 59
M SPLRFD ERGA VVVNDLGGDFKG+GKGS AA DKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+ IDS+GGV GAIG K PPFS AYTELE IMYALGVGAS+K+PK
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPK 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
D+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPR
Sbjct: 361 DMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPR 420
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVK 479
AG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQ KRTSDKVK
Sbjct: 421 AGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVK 480
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGF
Sbjct: 481 ATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGF 540
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVIS
Sbjct: 541 SARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVIS 600
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
NAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGN
Sbjct: 601 NAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGN 660
Query: 660 IGAKWT----------------IDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKL 703
I AKW+ IDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKL
Sbjct: 661 IAAKWSNRVISFSISLFLLLTAIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKL 720
Query: 704 DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 721 DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 753
>gi|148677987|gb|EDL09934.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Mus
musculus]
Length = 733
Score = 1214 bits (3141), Expect = 0.0, Method: Composition-based stats.
Identities = 585/736 (79%), Positives = 635/736 (86%), Gaps = 3/736 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFD ERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRI ILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIGD--QYFRILRDRSFSRISDEDWDIIH 118
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 119 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 178
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 179 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 238
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 239 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 298
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG + GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 299 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 357
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 358 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 417
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQ KRTS+K+K
Sbjct: 418 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 477
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 478 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 537
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 538 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 597
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 598 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 657
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 658 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 717
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 718 MLSQKLQMILKDYAKL 733
>gi|113911805|gb|AAI22585.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Bos taurus]
Length = 736
Score = 1214 bits (3141), Expect = 0.0, Method: Composition-based stats.
Identities = 587/736 (79%), Positives = 634/736 (86%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRF+ ERGA VVVNDLGGDF GVGKGSLAADKVVE
Sbjct: 1 MASTLRFNGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFTGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVEEGEK+VKTALDAFGRID+V+NNAGILRDRSF+RISDEDWD I
Sbjct: 61 EIRRKGGKAVANYDSVEEGEKIVKTALDAFGRIDIVINNAGILRDRSFSRISDEDWDKIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSASGIYGNFGQANY AAKLGLLGL+N LA+
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASGIYGNFGQANYCAAKLGLLGLSNCLAV 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSRMTQ+++PEDLVEALKP+YVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRMTQSILPEDLVEALKPDYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LGA+VRQ+ PMTPEAVKANW KICDF+NA+KP+SIQES GSI+E L+
Sbjct: 241 AGWIGKLRWERSLGALVRQRTQPMTPEAVKANWTKICDFDNATKPKSIQESIGSIVEALN 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KI+S G V AIG K PP +Y EL+ IMYALGVGASIK+PKD
Sbjct: 301 KINSGGEVSANPTSRATSATTSEFARAIGHKFPPLYSSYAELDTIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI+ QKS+M GGLAEIPGLSIN AK+LHGEQYLEL+KP+PRA
Sbjct: 361 MKFIYEGSSDFSCLPTFGVILAQKSIMNGGLAEIPGLSINLAKILHGEQYLELHKPIPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
GKL+CEA+VAD+LDKGSG+VI++DVY+YS +ELIC+NQ KRTSDK K
Sbjct: 421 GKLRCEAIVADILDKGSGLVILVDVYTYSGEELICYNQFSIFVVGSGGSGGKRTSDKAKA 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETG IVISN
Sbjct: 541 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGGIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKTPSEG LQST VFEEIGRRL+ IG EVVKKV AVFEWHITKG N
Sbjct: 601 AYVDLVPASAISAKTPSEGAGLQSTLVFEEIGRRLQGIGEEVVKKVRAVFEWHITKGENT 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPAKG+AD TI LSDEDFMEVVLGKLDPQKA FSGRLKARGNI
Sbjct: 661 AAKWTIDLKTGSGKVYQGPAKGSADVTITLSDEDFMEVVLGKLDPQKAVFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
+LSQKLQMILKDYAKL
Sbjct: 721 LLSQKLQMILKDYAKL 736
>gi|126352659|ref|NP_001075370.1| 17 beta-hydroxysteroid dehydrogenase type 4 [Equus caballus]
gi|45775304|gb|AAS77255.1| 17 beta-hydroxysteroid dehydrogenase type 4 [Equus caballus]
Length = 735
Score = 1214 bits (3141), Expect = 0.0, Method: Composition-based stats.
Identities = 591/736 (80%), Positives = 639/736 (86%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRFD ERGA VVVNDLGGD KGVGK SLAADKVVE
Sbjct: 1 MASQLRFDGRVVLVTGAGGGLGRAYALAFGERGASVVVNDLGGDMKGVGKSSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR RGGKAVA+YDSVE GEK+VKTALDAFGRIDVVVNNAGILRDRSF R+SDEDWDIIH
Sbjct: 61 EIRSRGGKAVASYDSVEAGEKIVKTALDAFGRIDVVVNNAGILRDRSFGRLSDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSASGIYGNFGQANYSAAKLGLLGL+N+LAI
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASGIYGNFGQANYSAAKLGLLGLSNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSR+TQTV PED+VEALKP+YVAPLVLWLCHESCEENG LFEVG
Sbjct: 181 EGKKNNIHCNTIAPQAGSRLTQTVFPEDVVEALKPDYVAPLVLWLCHESCEENGSLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGA+VRQ+N PMTPEAVKANWKKICDF + S PQ+IQESTG II ++S
Sbjct: 241 AGWIGKLRWERTLGALVRQRNQPMTPEAVKANWKKICDFGSVSNPQTIQESTGGIIGLVS 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DS GGV GAIGQKLP FS YTELEAIMYALGVGASIK+PKD
Sbjct: 301 KMDSNGGVSTNHTSHAASTATSGFVGAIGQKLPSFSSTYTELEAIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI QKSM+G LA+IPGLS++FAKVLHGEQYLELYKPLPR
Sbjct: 361 MKFIYEGSSDFSCLPTFGVITAQKSMLGE-LAQIPGLSLDFAKVLHGEQYLELYKPLPRT 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
GKLKCE VVAD+LDKGSGVVI++DVYSYS EL+C+NQ KRTSDK+KV
Sbjct: 420 GKLKCEGVVADILDKGSGVVILLDVYSYSGNELLCYNQFSLFLVGSGGFGGKRTSDKMKV 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDA+LTDTTSLNQAALYRLSGDWNPLHIDPNF+SLAGFDKPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAILTDTTSLNQAALYRLSGDWNPLHIDPNFSSLAGFDKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFAD+DVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVISN
Sbjct: 540 ARHVLQQFADHDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTS AKTPS+GG+LQST VFEEIGRRLKDIG +VVK VNAVFEWHIT+GGN
Sbjct: 600 AYVDLVPTSDMLAKTPSKGGELQSTLVFEEIGRRLKDIGHQVVKTVNAVFEWHITEGGNT 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
A WTIDLK+GSG+VYQGPA+G+ADTT+ LSDE FMEVV GKLDPQKAFFSG+LKA+GNI
Sbjct: 660 AATWTIDLKNGSGEVYQGPARGSADTTLTLSDEHFMEVVQGKLDPQKAFFSGKLKAKGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
M+SQKLQ ILKDYAKL
Sbjct: 720 MVSQKLQKILKDYAKL 735
>gi|56119094|ref|NP_001007810.1| hydroxysteroid (17-beta) dehydrogenase 4 [Bos taurus]
gi|51465240|emb|CAH17988.1| multifunctional protein 2 [Bos taurus]
Length = 736
Score = 1208 bits (3125), Expect = 0.0, Method: Composition-based stats.
Identities = 584/736 (79%), Positives = 632/736 (85%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRF+ ERGA VVVNDL GDF GVGKGSL+ADKVVE
Sbjct: 1 MASTLRFNGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLRGDFTGVGKGSLSADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVEEGEK+VKTALDAFGRID+V+NNAGILRDRSF+RISDEDWD I
Sbjct: 61 EIRRKGGKAVANYDSVEEGEKIVKTALDAFGRIDIVINNAGILRDRSFSRISDEDWDKIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSAS IYGNFGQANY AAKLGLLGL+N LA+
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASRIYGNFGQANYCAAKLGLLGLSNCLAV 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSRMTQ+++PEDLVEALKP+YVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRMTQSILPEDLVEALKPDYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LGA+VRQ+ PMTPEAVKANW KICDF+NA+KP+SIQES GSI+E L+
Sbjct: 241 AGWIGKLRWERSLGALVRQRTQPMTPEAVKANWTKICDFDNATKPKSIQESIGSIVEALN 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KI+S G V AIG K PP +Y EL+ IMYALGVGASIK+PKD
Sbjct: 301 KINSGGEVSANPTSRATSATTSEFARAIGHKFPPLYSSYAELDTIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI+ QKS+M GGLAEIPGLSIN AK+LHGEQYLEL+KP+PRA
Sbjct: 361 MKFIYEGSSDFSCLPTFGVILAQKSIMNGGLAEIPGLSINLAKILHGEQYLELHKPIPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
GKL+CEA+VAD+LDKGSG+VI++DVY+YS +ELIC+NQ KRTSDK K
Sbjct: 421 GKLRCEAIVADILDKGSGLVILVDVYTYSGEELICYNQFSIFVVGSGGSGGKRTSDKAKA 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETG IVISN
Sbjct: 541 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGGIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKTPSEG LQST VFEEIGRRL+ IG EVVKKV AVFEWHITKG N
Sbjct: 601 AYVDLVPASAISAKTPSEGAGLQSTLVFEEIGRRLQGIGEEVVKKVRAVFEWHITKGENT 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPAKG+AD TI LSDEDFMEVVLGKLDPQKA FSGRLKARGNI
Sbjct: 661 AAKWTIDLKTGSGKVYQGPAKGSADVTITLSDEDFMEVVLGKLDPQKAVFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
+LSQKLQMILKDYAKL
Sbjct: 721 LLSQKLQMILKDYAKL 736
>gi|3005897|emb|CAA73945.1| mutifunctional protein2 [Cavia porcellus]
Length = 735
Score = 1200 bits (3105), Expect = 0.0, Method: Composition-based stats.
Identities = 577/736 (78%), Positives = 641/736 (87%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFD ERGA V+V+DLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVIVDDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GG+AVANYDSVE GEK+VK ALDAFGRIDVVVNNAGIL RSF+RISDEDWDI+H
Sbjct: 61 EIRRKGGRAVANYDSVEAGEKIVKAALDAFGRIDVVVNNAGILTHRSFSRISDEDWDIVH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHL GSFQVTRAAW HMKKQ YGRIIMT+S++GIYGNFGQANYSAAKLGLLGL+N++AI
Sbjct: 121 RVHLWGSFQVTRAAWNHMKKQNYGRIIMTTSSAGIYGNFGQANYSAAKLGLLGLSNTIAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSR+TQTVMP+DLV+ALKPEYVAPLVLWLCH+SCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRLTQTVMPDDLVQALKPEYVAPLVLWLCHDSCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR+KN P+TPE VKANWKKICDF+NASKPQSIQESTG ++E+L
Sbjct: 241 AGWIGKLRWERTLGAIVRRKNEPVTPETVKANWKKICDFDNASKPQSIQESTGGMVEILH 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE V AIG KLP FS +YTEL+ IMYALGVGAS+KDPK+
Sbjct: 301 KIDSEE-VSTNPTSHATSTASPGYASAIGYKLPSFSPSYTELDCIMYALGVGASVKDPKN 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEGS DFSCLPTFGVI+ QKS+ GGGLA++ GLSINFAKVLHGEQYL++YKP PRA
Sbjct: 360 LRFLYEGSPDFSCLPTFGVIVAQKSVFGGGLADVSGLSINFAKVLHGEQYLQIYKPFPRA 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
GKLKCEAV+AD+LDKGSG+VI++DVY+YS +ELIC+NQ KRTS+K+KV
Sbjct: 420 GKLKCEAVIADILDKGSGLVIVLDVYAYSGEELICYNQFSVFVVGSGGFGGKRTSEKLKV 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIP+RPPDAV+TD TSL+QAALYRLSGDWNPLHIDPNFAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAIPSRPPDAVITDNTSLDQAALYRLSGDWNPLHIDPNFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVS+FKAIK RFAKPVYPGQTL+TEMWKEGNRIHFQTK+ ETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSKFKAIKVRFAKPVYPGQTLKTEMWKEGNRIHFQTKILETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKT EGG+LQST VFEEI RRLKDIG + VKKVNAVFEWHITKGGN
Sbjct: 600 AYVDLVPPSDLSAKTHPEGGELQSTRVFEEINRRLKDIGHKEVKKVNAVFEWHITKGGNT 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPA+G+ADT+I++SDEDFMEVVLGKLDPQKAFFSGRLKA+GNI
Sbjct: 660 AAKWTIDLKNGSGKVYQGPAEGSADTSILISDEDFMEVVLGKLDPQKAFFSGRLKAKGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYA L
Sbjct: 720 MLSQKLQMILKDYANL 735
>gi|149064233|gb|EDM14436.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Rattus
norvegicus]
Length = 708
Score = 1184 bits (3063), Expect = 0.0, Method: Composition-based stats.
Identities = 573/706 (81%), Positives = 617/706 (87%), Gaps = 1/706 (0%)
Query: 1 MGSPLRFDXXXXXXXXXXXXXXXXXXXXXXERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFD ERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG + G +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQ KRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQ 706
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQ 705
>gi|47523670|ref|NP_999471.1| hydroxysteroid (17-beta) dehydrogenase 4 [Sus scrofa]
gi|499340|emb|CAA55037.1| 17beta-estradiol dehydrogenase [Sus scrofa]
Length = 737
Score = 1179 bits (3049), Expect = 0.0, Method: Composition-based stats.
Identities = 579/707 (81%), Positives = 625/707 (88%), Gaps = 1/707 (0%)
Query: 31 ERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAF 90
ERGA VVVNDLGGD KGVGKGSLAADKVVEEIRR+GGKAVANYDSVE GEK+VK ALDAF
Sbjct: 31 ERGASVVVNDLGGDMKGVGKGSLAADKVVEEIRRKGGKAVANYDSVEAGEKIVKAALDAF 90
Query: 91 GRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTS 150
GRIDVVVNNAGILRDRSF+RISDEDWD+I RVHLRGSF VTRAAW+HMKKQ +GRIIMTS
Sbjct: 91 GRIDVVVNNAGILRDRSFSRISDEDWDMIQRVHLRGSFMVTRAAWDHMKKQNFGRIIMTS 150
Query: 151 SASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLV 210
SA+GIYGNFGQANYSAAKLGLLGL+NSLA+EG+K+NIHCNT+AP AGSRMTQ +PEDL+
Sbjct: 151 SAAGIYGNFGQANYSAAKLGLLGLSNSLAVEGKKNNIHCNTVAPVAGSRMTQGFLPEDLI 210
Query: 211 EALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVK 270
EALKPEYVAPLVLWLCHESCEENG +FEVGAGWIGKLRWERTLGA+VRQKN PMTPEAVK
Sbjct: 211 EALKPEYVAPLVLWLCHESCEENGSVFEVGAGWIGKLRWERTLGALVRQKNQPMTPEAVK 270
Query: 271 ANWKKICDFENASKPQSIQESTGSIIEVLSKIDS-EGGVXXXXXXXXXXXXXXXXXGAIG 329
ANW KICDF+NA+KPQ IQ+S ++IE LSKIDS +GG+ A+G
Sbjct: 271 ANWTKICDFDNATKPQRIQDSVSTVIEALSKIDSSDGGISANNLSHATSAAPSGLVEAVG 330
Query: 330 QKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGG 389
K PPFS +YTE++ IMYA GVGASIK+PKDLKFIYEG+SDFSCLPTFGVI+ QKS+ GG
Sbjct: 331 YKFPPFSSSYTEVDTIMYAFGVGASIKEPKDLKFIYEGNSDFSCLPTFGVILAQKSLGGG 390
Query: 390 GLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYS 449
GLAEIPGLS+NF KVLHGE YLELYKPLP AG LKCEAVVADVLDK SG+VI++DVYSYS
Sbjct: 391 GLAEIPGLSVNFTKVLHGEHYLELYKPLPNAGDLKCEAVVADVLDKRSGLVILIDVYSYS 450
Query: 450 EKELICHNQXXXXXXXXXXXXXKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSG 509
KELIC+NQ KRTSDK KVAVAIPNRPPDA+LTDTTSLNQAALYRLSG
Sbjct: 451 GKELICYNQFSVFVMGSGGFGGKRTSDKDKVAVAIPNRPPDAILTDTTSLNQAALYRLSG 510
Query: 510 DWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYP 569
DWNPLHIDP+FASLAGFD+PILHGLCTFGFSAR VLQQ+AD DV RFKAIK RFAKPVYP
Sbjct: 511 DWNPLHIDPDFASLAGFDRPILHGLCTFGFSARHVLQQYADRDVLRFKAIKVRFAKPVYP 570
Query: 570 GQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFE 629
GQTLQTEMWKEGNRIHFQTKVQETGD VISNAYVDL PTS T AK PSEGG LQS VFE
Sbjct: 571 GQTLQTEMWKEGNRIHFQTKVQETGDTVISNAYVDLVPTSDTLAKIPSEGGDLQSNLVFE 630
Query: 630 EIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTII 689
EIGRRL+DIG E+VKKVNAVFEWHITKG I AKWTIDLK+G+GKVYQGPAKG+AD T I
Sbjct: 631 EIGRRLQDIGQEMVKKVNAVFEWHITKGEKIAAKWTIDLKNGAGKVYQGPAKGSADATFI 690
Query: 690 LSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
LSDE FMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAK+
Sbjct: 691 LSDEVFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKI 737
>gi|126333832|ref|XP_001378211.1| PREDICTED: similar to 17beta-hydroxysteroid dehydrogenase
[Monodelphis domestica]
Length = 719
Score = 1152 bits (2980), Expect = 0.0, Method: Composition-based stats.
Identities = 542/700 (77%), Positives = 617/700 (88%), Gaps = 1/700 (0%)
Query: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVV 97
VNDLGGDFKGVG+ S AAD VVEEI++RGGKAVANYDSVE GEKVVKTALDAFG+ID+V+
Sbjct: 20 VNDLGGDFKGVGRSSSAADNVVEEIKKRGGKAVANYDSVEAGEKVVKTALDAFGKIDIVI 79
Query: 98 NNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYG 157
NNAGILRDRSF RISDEDWDIIH+VHLRGSFQVTRAAW+HMKKQK+GRIIMTSSASGIYG
Sbjct: 80 NNAGILRDRSFVRISDEDWDIIHKVHLRGSFQVTRAAWDHMKKQKFGRIIMTSSASGIYG 139
Query: 158 NFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEY 217
NFGQANYSAAKLGL GL+N+LAIEGRK NIHCNTIAP AGSRMT++VMP+DLV+ALKP+Y
Sbjct: 140 NFGQANYSAAKLGLAGLSNTLAIEGRKFNIHCNTIAPTAGSRMTESVMPQDLVDALKPDY 199
Query: 218 VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKIC 277
VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKN PMTPEAVKANW+KIC
Sbjct: 200 VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNQPMTPEAVKANWRKIC 259
Query: 278 DFENASKPQSIQESTGSIIEVLSKIDSEGGVXXXXXXXXXXXXXXXXXGAIGQKLPPFSY 337
DFENA+ PQ+IQEST S+IEVL+KIDS+GGV AIG KLPP ++
Sbjct: 260 DFENANHPQTIQESTASVIEVLNKIDSQGGVSMNHTSQAASATTAAFTTAIGYKLPPRTF 319
Query: 338 AYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGL 397
+YTELEAIMYALGVGAS+K+P++LKF+YEG+SDFSCLPTFGVI QK MM GGL+E+PGL
Sbjct: 320 SYTELEAIMYALGVGASVKNPENLKFVYEGNSDFSCLPTFGVIPAQKCMMDGGLSEVPGL 379
Query: 398 SINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHN 457
+I++ KVLHGEQYLELYKPLP+ G+L EA++ D+LDKGSG+VI++DVYSYS KELIC N
Sbjct: 380 TIDYTKVLHGEQYLELYKPLPKTGQLTNEAIIVDILDKGSGLVILLDVYSYSGKELICFN 439
Query: 458 QXXXXXXXXXXXXXKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHID 517
Q K+TSDK KV V P RPPDA+LTDTTSLNQA LYRLSGDWNPLHID
Sbjct: 440 QFTVFVVGSGGFGGKKTSDKAKVTVPPPKRPPDAILTDTTSLNQAVLYRLSGDWNPLHID 499
Query: 518 PNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEM 577
P+FASL GF+KPILHGLC+FG++AR +LQQF +NDVSRF+AIKARFAKPVYPGQTL TEM
Sbjct: 500 PSFASLGGFEKPILHGLCSFGYAARHILQQFGNNDVSRFRAIKARFAKPVYPGQTLLTEM 559
Query: 578 WKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGT-SAKTPSEGGKLQSTFVFEEIGRRLK 636
WKEGNRIHFQTKVQETGDIV+SNAYVDL PTS S K S+ G LQST VFEEIGRR+K
Sbjct: 560 WKEGNRIHFQTKVQETGDIVLSNAYVDLVPTSDVLSTKVSSKDGTLQSTLVFEEIGRRIK 619
Query: 637 DIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFM 696
D+G E+VKKVNAVF+W+ITK G A+WTIDLK+GSG++YQGPA+G+ADT+ LSDE+FM
Sbjct: 620 DVGKELVKKVNAVFQWNITKHGQTAAQWTIDLKNGSGELYQGPARGSADTSFTLSDENFM 679
Query: 697 EVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
EVVLGKL+PQKAFFSG+L+ +GNIMLSQKL+MILKD+AKL
Sbjct: 680 EVVLGKLNPQKAFFSGKLQVKGNIMLSQKLEMILKDHAKL 719
>gi|119569295|gb|EAW48910.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_a [Homo
sapiens]
Length = 596
Score = 1146 bits (2964), Expect = 0.0, Method: Composition-based stats.
Identities = 566/599 (94%), Positives = 566/599 (94%), Gaps = 3/599 (0%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQK IIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG
Sbjct: 1 MKKQK---IIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 57
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV
Sbjct: 58 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 117
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVXXXXXXXXX 317
RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGV
Sbjct: 118 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 177
Query: 318 XXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
GAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF
Sbjct: 178 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 237
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS
Sbjct: 238 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 297
Query: 438 GVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKVAVAIPNRPPDAVLTDTT 497
GVVIIMDVYSYSEKELICHNQ KRTSDKVKVAVAIPNRPPDAVLTDTT
Sbjct: 298 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 357
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK
Sbjct: 358 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 417
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS
Sbjct: 418 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 477
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ
Sbjct: 478 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 537
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 538 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 596
>gi|109078307|ref|XP_001088200.1| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 isoform 3
[Macaca mulatta]
Length = 597
Score = 1114 bits (2882), Expect = 0.0, Method: Composition-based stats.
Identities = 552/599 (92%), Positives = 559/599 (93%), Gaps = 2/599 (0%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG
Sbjct: 1 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 60
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV
Sbjct: 61 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 120
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVXXXXXXXXX 317
RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEG V
Sbjct: 121 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEG-VSANHTSHAT 179
Query: 318 XXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
GAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKF+YEGSSDFSCLPTF
Sbjct: 180 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFVYEGSSDFSCLPTF 239
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVIIGQKS+MGGGLAEIPGLSINFAKV+ GE ++ KPL R GKLKCEAVVADVLDKGS
Sbjct: 240 GVIIGQKSLMGGGLAEIPGLSINFAKVI-GEPSMKAEKPLKRVGKLKCEAVVADVLDKGS 298
Query: 438 GVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKVAVAIPNRPPDAVLTDTT 497
GVVIIMDVYSYSEKELICHNQ KRTSDKVKVAVAIPNRPPDAVLTDTT
Sbjct: 299 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 358
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARR+LQQFADNDVSRFK
Sbjct: 359 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRILQQFADNDVSRFK 418
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTS TSAKTPS
Sbjct: 419 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSDTSAKTPS 478
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGGKLQST VFEEIGRRLKD+GPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ
Sbjct: 479 EGGKLQSTLVFEEIGRRLKDVGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 538
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 539 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 597
>gi|73970529|ref|XP_859266.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 3 [Canis familiaris]
Length = 599
Score = 1036 bits (2680), Expect = 0.0, Method: Composition-based stats.
Identities = 495/599 (82%), Positives = 530/599 (88%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LAIEG+ SNIHCNTIAP AG
Sbjct: 1 MKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLAIEGKTSNIHCNTIAPTAG 60
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEVG GWIGKLRWERTLGAIV
Sbjct: 61 SRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEVGGGWIGKLRWERTLGAIV 120
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVXXXXXXXXX 317
RQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V++ IDS+GGV
Sbjct: 121 RQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVVNTIDSDGGVSTNHTSHAA 180
Query: 318 XXXXXXXXGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
GAIG K PPFS AYTELE IMYALGVGAS+K+PKD+KFIYEGS+DFSCLPTF
Sbjct: 181 STATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPKDMKFIYEGSTDFSCLPTF 240
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPRAG L+CEAVVADVLDKGS
Sbjct: 241 GVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPRAGNLRCEAVVADVLDKGS 300
Query: 438 GVVIIMDVYSYSEKELICHNQXXXXXXXXXXXXXKRTSDKVKVAVAIPNRPPDAVLTDTT 497
G VI++DVYSY E+ELIC+NQ KRTSDKVK VA+PNRPPDAVLTDTT
Sbjct: 301 GSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVKATVAVPNRPPDAVLTDTT 360
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGFSAR VLQ+FADNDVSRFK
Sbjct: 361 SLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGFSARHVLQKFADNDVSRFK 420
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVISNAYVDL PTS TSA+TPS
Sbjct: 421 AIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVISNAYVDLMPTSDTSAQTPS 480
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGNI AKWTIDLKSG GKVYQ
Sbjct: 481 EGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGNIAAKWTIDLKSGFGKVYQ 540
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 541 GPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 599