BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= ENSG00000176876__[Homo_sapiens]
(195 letters)
Database: nr.pal
6,348,806 sequences; 2,166,943,470 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923892|ref|NP_061133.1| peroxisomal membrane protein 2,... 266 8e-70
gi|109099313|ref|XP_001083110.1| PREDICTED: similar to Pero... 261 1e-68
gi|114050981|ref|NP_001039473.1| peroxisomal membrane prote... 234 3e-60
gi|169205662|ref|XP_001714007.1| PREDICTED: similar to 22kD... 231 1e-59
gi|114647910|ref|XP_001152082.1| PREDICTED: similar to 22kD... 219 7e-56
gi|119575215|gb|EAW54828.1| peroxisomal membrane protein 2,... 215 1e-54
gi|149063733|gb|EDM14056.1| peroxisomal membrane protein 2,... 214 3e-54
gi|13928796|ref|NP_113775.1| peroxisomal membrane protein 2... 214 3e-54
gi|57105752|ref|XP_543347.1| PREDICTED: similar to Peroxiso... 208 2e-52
gi|149756812|ref|XP_001493559.1| PREDICTED: similar to Pero... 206 9e-52
gi|1172540|sp|P42925|PXMP2_MOUSE Peroxisomal membrane prote... 191 3e-47
gi|149634336|ref|XP_001509760.1| PREDICTED: similar to Pero... 189 6e-47
gi|112421058|ref|NP_033019.2| peroxisomal membrane protein ... 189 1e-46
gi|119575216|gb|EAW54829.1| peroxisomal membrane protein 2,... 187 4e-46
gi|126323846|ref|XP_001366379.1| PREDICTED: similar to Pero... 182 9e-45
gi|52219060|ref|NP_001004607.1| hypothetical protein LOC447... 171 3e-41
gi|55742326|ref|NP_001006885.1| peroxisomal membrane protei... 167 4e-40
gi|148232453|ref|NP_001088759.1| hypothetical protein LOC49... 164 2e-39
gi|47226497|emb|CAG08513.1| unnamed protein product [Tetrao... 157 2e-37
gi|156359662|ref|XP_001624885.1| predicted protein [Nematos... 119 1e-25
gi|149063732|gb|EDM14055.1| peroxisomal membrane protein 2,... 117 5e-25
gi|72124564|ref|XP_789205.1| PREDICTED: similar to peroxiso... 100 6e-20
gi|148688082|gb|EDL20029.1| peroxisomal membrane protein 2,... 91 6e-17
gi|66513493|ref|XP_623568.1| PREDICTED: similar to CG7970-P... 86 1e-15
gi|76664098|emb|CAI59818.2| MPV17 protein [Nyctotherus ovalis] 84 5e-15
gi|116056508|emb|CAL52797.1| Peroxisomal membrane protein M... 83 1e-14
gi|33187760|gb|AAP97734.1| liver regeneration-related prote... 82 2e-14
gi|145344153|ref|XP_001416602.1| predicted protein [Ostreoc... 80 7e-14
gi|157347636|emb|CAO18273.1| unnamed protein product [Vitis... 80 1e-13
gi|159474366|ref|XP_001695296.1| peroxisomal membrane MPV17... 79 1e-13
gi|109140438|ref|XP_001115084.1| PREDICTED: similar to Pero... 79 1e-13
gi|114618730|ref|XP_001174859.1| PREDICTED: similar to 22kD... 78 3e-13
gi|91090900|ref|XP_973581.1| PREDICTED: similar to CG7970-P... 75 3e-12
gi|118787443|ref|XP_316087.3| AGAP006040-PA [Anopheles gamb... 75 3e-12
gi|66803743|ref|XP_635703.1| hypothetical protein DDBDRAFT_... 75 3e-12
gi|21594286|gb|AAM65990.1| unknown [Arabidopsis thaliana] 75 3e-12
gi|16648746|gb|AAL25565.1| AT5g19750/T29J13_170 [Arabidopsi... 74 6e-12
gi|15241166|ref|NP_197476.1| peroxisomal membrane 22 kDa fa... 74 6e-12
gi|159467795|ref|XP_001692077.1| hypothetical protein CHLRE... 73 1e-11
gi|66816891|ref|XP_642423.1| hypothetical protein DDBDRAFT_... 73 1e-11
gi|147769694|emb|CAN61275.1| hypothetical protein [Vitis vi... 73 1e-11
gi|168014733|ref|XP_001759906.1| predicted protein [Physcom... 72 1e-11
gi|46107694|ref|XP_380906.1| hypothetical protein FG00730.1... 72 2e-11
gi|168064329|ref|XP_001784115.1| predicted protein [Physcom... 72 2e-11
gi|168012591|ref|XP_001758985.1| predicted protein [Physcom... 72 2e-11
gi|121719450|ref|XP_001276424.1| integral membrane protein,... 71 4e-11
gi|154323324|ref|XP_001560976.1| hypothetical protein BC1G_... 71 4e-11
gi|118792075|ref|XP_001238256.1| AGAP012415-PA [Anopheles g... 70 7e-11
gi|157113651|ref|XP_001652038.1| peroxisomal membrane prote... 70 9e-11
gi|94469040|gb|ABF18369.1| peroxisomal membrane protein [Ae... 70 1e-10
gi|164429710|ref|XP_963854.2| hypothetical protein NCU02117... 69 2e-10
gi|156057949|ref|XP_001594898.1| hypothetical protein SS1G_... 68 4e-10
gi|157111701|ref|XP_001651690.1| mpv17 protein [Aedes aegyp... 67 6e-10
gi|157111703|ref|XP_001651691.1| mpv17 protein [Aedes aegyp... 67 7e-10
gi|94469100|gb|ABF18399.1| hypothetical conserved protein [... 67 7e-10
gi|114053251|ref|NP_001040524.1| peroxisomal membrane prote... 66 1e-09
gi|145241838|ref|XP_001393565.1| hypothetical protein An09g... 66 1e-09
gi|77548545|gb|ABA91342.1| Mpv17/PMP22 family protein, expr... 66 2e-09
gi|157107412|ref|XP_001649765.1| pmp22 peroxisomal membrane... 65 2e-09
gi|116182182|ref|XP_001220940.1| hypothetical protein CHGG_... 65 2e-09
gi|87241014|gb|ABD32872.1| WD-40 repeat [Medicago truncatula] 65 2e-09
gi|147905308|ref|NP_001090480.1| hypothetical protein LOC77... 65 2e-09
gi|157349028|emb|CAO24106.1| unnamed protein product [Vitis... 65 2e-09
gi|157107414|ref|XP_001649766.1| pmp22 peroxisomal membrane... 65 3e-09
gi|159471962|ref|XP_001694125.1| predicted protein [Chlamyd... 65 4e-09
gi|159466216|ref|XP_001691305.1| predicted protein [Chlamyd... 64 4e-09
gi|118488904|gb|ABK96261.1| unknown [Populus trichocarpa x ... 64 4e-09
gi|91094217|ref|XP_973172.1| PREDICTED: similar to MpV17 tr... 64 5e-09
gi|21358267|ref|NP_647641.1| CG7970 CG7970-PA [Drosophila m... 64 6e-09
gi|21553640|gb|AAM62733.1| contains similarity to 22 kDa pe... 63 1e-08
gi|157342806|emb|CAO65518.1| unnamed protein product [Vitis... 63 1e-08
gi|18422298|ref|NP_568621.1| peroxisomal membrane 22 kDa fa... 63 1e-08
gi|152013707|gb|ABS19969.1| integral membrane protein mvp17... 63 1e-08
gi|115492813|ref|XP_001211034.1| conserved hypothetical pro... 63 1e-08
gi|19114608|ref|NP_593696.1| Mvp17/PMP22 family [Schizosacc... 62 2e-08
gi|30794097|gb|AAP40491.1| unknown protein [Arabidopsis tha... 62 2e-08
gi|18406056|ref|NP_565983.1| peroxisomal membrane 22 kDa fa... 62 2e-08
gi|134107321|ref|XP_777545.1| hypothetical protein CNBA6670... 62 3e-08
gi|170056943|ref|XP_001864260.1| sym-1 [Culex pipiens quinq... 62 3e-08
gi|125535658|gb|EAY82146.1| hypothetical protein OsI_036105... 62 3e-08
gi|42572817|ref|NP_974505.1| peroxisomal membrane protein-r... 61 3e-08
gi|15226016|ref|NP_179092.1| peroxisomal membrane protein 2... 61 4e-08
gi|170051600|ref|XP_001861838.1| mpv17 protein [Culex pipie... 61 4e-08
gi|159125847|gb|EDP50963.1| integral membrane protein, Mpv1... 61 5e-08
gi|170039454|ref|XP_001847549.1| pmp22 peroxisomal membrane... 61 5e-08
gi|66804071|ref|XP_635840.1| hypothetical protein DDBDRAFT_... 60 6e-08
gi|70985438|ref|XP_748225.1| integral membrane protein, Mpv... 60 7e-08
gi|115453925|ref|NP_001050563.1| Os03g0583800 [Oryza sativa... 60 7e-08
gi|42566274|ref|NP_192250.2| peroxisomal membrane protein-r... 60 7e-08
gi|30695366|ref|NP_564615.3| peroxisomal membrane protein-r... 60 8e-08
gi|164608820|gb|ABY62741.1| integral membrane protein [Arte... 60 9e-08
gi|77553570|gb|ABA96366.1| Mpv17/PMP22 family protein, expr... 60 9e-08
gi|50312141|ref|XP_456102.1| unnamed protein product [Kluyv... 60 9e-08
gi|169785587|ref|XP_001827254.1| [Aspergillus oryzae] >gi|9... 59 1e-07
gi|169616350|ref|XP_001801590.1| hypothetical protein SNOG_... 59 1e-07
gi|157357420|emb|CAO63954.1| unnamed protein product [Vitis... 59 2e-07
gi|168048757|ref|XP_001776832.1| predicted protein [Physcom... 59 2e-07
gi|157338182|emb|CAO39226.1| unnamed protein product [Vitis... 59 2e-07
gi|121709367|ref|XP_001272400.1| integral membrane protein,... 59 2e-07
gi|71018247|ref|XP_759354.1| hypothetical protein UM03207.1... 58 3e-07
>gi|8923892|ref|NP_061133.1| peroxisomal membrane protein 2, 22kDa [Homo sapiens]
gi|27923831|sp|Q9NR77|PXMP2_HUMAN Peroxisomal membrane protein 2 (22 kDa peroxisomal membrane
protein)
gi|8164184|gb|AAF73963.1| 22kDa peroxisomal membrane protein-like [Homo sapiens]
gi|15422171|gb|AAK95858.1| 22 kDa peroxisomal membrane protein 2 [Homo sapiens]
gi|49522857|gb|AAH73997.1| Peroxisomal membrane protein 2, 22kDa [Homo sapiens]
Length = 195
Score = 266 bits (679), Expect = 8e-70, Method: Composition-based stats.
Identities = 151/172 (87%), Positives = 151/172 (87%)
Query: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFT 83
QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFT
Sbjct: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFT 83
Query: 84 GPLSHFFYFFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAK 143
GPLSHFFYFFMEHWIPPEVPLAG VFAPA EGKDASAFAAK
Sbjct: 84 GPLSHFFYFFMEHWIPPEVPLAGLRRLLLDRLVFAPAFLMLFFLIMNFLEGKDASAFAAK 143
Query: 144 MRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
MRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK
Sbjct: 144 MRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
>gi|109099313|ref|XP_001083110.1| PREDICTED: similar to Peroxisomal membrane protein 2 (22 kDa
peroxisomal membrane protein) [Macaca mulatta]
Length = 195
Score = 261 bits (668), Expect = 1e-68, Method: Composition-based stats.
Identities = 146/172 (84%), Positives = 149/172 (86%)
Query: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFT 83
QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKE+SRSLDVGGPLRYAVYGFFFT
Sbjct: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKEHSRSLDVGGPLRYAVYGFFFT 83
Query: 84 GPLSHFFYFFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAK 143
GPLSHFFY FMEHWIPPEVPLAG VFAPA EGKDASAFA K
Sbjct: 84 GPLSHFFYLFMEHWIPPEVPLAGLRRLLLDRLVFAPAFLMLFFLIMNFLEGKDASAFATK 143
Query: 144 MRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
MRGGFWPALRMNWRVWTP+QFININY+PLKFRVLFANLAALFWYAYLASLGK
Sbjct: 144 MRGGFWPALRMNWRVWTPVQFININYIPLKFRVLFANLAALFWYAYLASLGK 195
>gi|114050981|ref|NP_001039473.1| peroxisomal membrane protein 2, 22kDa [Bos taurus]
gi|110287796|sp|Q2KIY1|PXMP2_BOVIN Peroxisomal membrane protein 2
gi|86827593|gb|AAI12466.1| Peroxisomal membrane protein 2, 22kDa [Bos taurus]
Length = 196
Score = 234 bits (596), Expect = 3e-60, Method: Composition-based stats.
Identities = 127/173 (73%), Positives = 139/173 (80%), Gaps = 1/173 (0%)
Query: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKEN-SRSLDVGGPLRYAVYGFFF 82
QYL LRLYPVLTKAATSGILSALGNFLAQ+IEKK+KKEN S+ LDV GPLRYA+YGFFF
Sbjct: 24 QYLRLLRLYPVLTKAATSGILSALGNFLAQLIEKKQKKENCSQKLDVSGPLRYAIYGFFF 83
Query: 83 TGPLSHFFYFFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAA 142
TGPL HFFY ME WIP EVPLAG +FAPA EG+D +AFAA
Sbjct: 84 TGPLGHFFYLLMERWIPSEVPLAGIKRLLLDRLLFAPAFLSLFFLVMNFLEGQDTAAFAA 143
Query: 143 KMRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
KM+ GFWPALRMNWRVWTP+QFININY+P++FRVLFANL ALFWYAYLASLGK
Sbjct: 144 KMKSGFWPALRMNWRVWTPVQFININYIPVQFRVLFANLVALFWYAYLASLGK 196
>gi|169205662|ref|XP_001714007.1| PREDICTED: similar to 22kDa peroxisomal membrane protein-like [Homo
sapiens]
Length = 376
Score = 231 bits (590), Expect = 1e-59, Method: Composition-based stats.
Identities = 114/145 (78%), Positives = 116/145 (80%)
Query: 29 LRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSH 88
+R V T+ GILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSH
Sbjct: 121 VRTARVETRPGKVGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSH 180
Query: 89 FFYFFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGF 148
FFYFFMEHWIPPEVPLAG VFAPA EGKDASAFAAKMRGGF
Sbjct: 181 FFYFFMEHWIPPEVPLAGLRRLLLDRLVFAPAFLMLFFLIMNFLEGKDASAFAAKMRGGF 240
Query: 149 WPALRMNWRVWTPLQFININYVPLK 173
WPALRMNWRVWTPLQFININYVPLK
Sbjct: 241 WPALRMNWRVWTPLQFININYVPLK 265
>gi|114647910|ref|XP_001152082.1| PREDICTED: similar to 22kDa peroxisomal membrane protein-like [Pan
troglodytes]
Length = 361
Score = 219 bits (558), Expect = 7e-56, Method: Composition-based stats.
Identities = 113/145 (77%), Positives = 115/145 (79%)
Query: 29 LRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSH 88
+R V T+ GILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSH
Sbjct: 106 VRTARVETRPGKVGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSH 165
Query: 89 FFYFFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGF 148
FFYFFMEHWIPPEVPLAG V APA EGKDASAFAAKMRGGF
Sbjct: 166 FFYFFMEHWIPPEVPLAGLRRLLLDRLVLAPAFLMLFFLIMNFLEGKDASAFAAKMRGGF 225
Query: 149 WPALRMNWRVWTPLQFININYVPLK 173
WPALRMNWRVWTPLQFININYVPLK
Sbjct: 226 WPALRMNWRVWTPLQFININYVPLK 250
>gi|119575215|gb|EAW54828.1| peroxisomal membrane protein 2, 22kDa, isoform CRA_a [Homo sapiens]
Length = 142
Score = 215 bits (547), Expect = 1e-54, Method: Composition-based stats.
Identities = 121/142 (85%), Positives = 121/142 (85%)
Query: 54 MIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIPPEVPLAGXXXXXXX 113
MIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIPPEVPLAG
Sbjct: 1 MIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIPPEVPLAGLRRLLLD 60
Query: 114 XXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGFWPALRMNWRVWTPLQFININYVPLK 173
VFAPA EGKDASAFAAKMRGGFWPALRMNWRVWTPLQFININYVPLK
Sbjct: 61 RLVFAPAFLMLFFLIMNFLEGKDASAFAAKMRGGFWPALRMNWRVWTPLQFININYVPLK 120
Query: 174 FRVLFANLAALFWYAYLASLGK 195
FRVLFANLAALFWYAYLASLGK
Sbjct: 121 FRVLFANLAALFWYAYLASLGK 142
>gi|149063733|gb|EDM14056.1| peroxisomal membrane protein 2, isoform CRA_b [Rattus norvegicus]
Length = 194
Score = 214 bits (545), Expect = 3e-54, Method: Composition-based stats.
Identities = 118/172 (68%), Positives = 132/172 (76%), Gaps = 1/172 (0%)
Query: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFT 83
QYLLFL+ YPV+TKA +SGILSALGN LAQMIEKK+KK+ SRSL+V G LRY VYG F T
Sbjct: 24 QYLLFLKFYPVVTKAVSSGILSALGNLLAQMIEKKQKKD-SRSLEVSGLLRYLVYGLFVT 82
Query: 84 GPLSHFFYFFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAK 143
GPLSH+ Y FME+W+PPEVP A FAP EGK+ S F AK
Sbjct: 83 GPLSHYLYLFMEYWVPPEVPWARVKRLLLDRLFFAPTFLLLFFFVMNLLEGKNISVFVAK 142
Query: 144 MRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
MR GFWPAL+MNWR+WTPLQFININYVPL+FRVLFAN+AALFWYAYLASLGK
Sbjct: 143 MRSGFWPALQMNWRMWTPLQFININYVPLQFRVLFANMAALFWYAYLASLGK 194
>gi|13928796|ref|NP_113775.1| peroxisomal membrane protein 2 [Rattus norvegicus]
gi|585703|sp|Q07066|PXMP2_RAT Peroxisomal membrane protein 2 (22 kDa peroxisomal membrane
protein)
gi|297437|emb|CAA49756.1| peroxisomal membrane protein [Rattus norvegicus]
Length = 194
Score = 214 bits (545), Expect = 3e-54, Method: Composition-based stats.
Identities = 118/172 (68%), Positives = 132/172 (76%), Gaps = 1/172 (0%)
Query: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFT 83
QYLLFL+ YPV+TKA +SGILSALGN LAQMIEKK+KK+ SRSL+V G LRY VYG F T
Sbjct: 24 QYLLFLKFYPVVTKAVSSGILSALGNLLAQMIEKKQKKD-SRSLEVSGLLRYLVYGLFVT 82
Query: 84 GPLSHFFYFFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAK 143
GPLSH+ Y FME+W+PPEVP A FAP EGK+ S F AK
Sbjct: 83 GPLSHYLYLFMEYWVPPEVPWARVKRLLLDRLFFAPTFLLLFFFVMNLLEGKNISVFVAK 142
Query: 144 MRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
MR GFWPAL+MNWR+WTPLQFININYVPL+FRVLFAN+AALFWYAYLASLGK
Sbjct: 143 MRSGFWPALQMNWRMWTPLQFININYVPLQFRVLFANMAALFWYAYLASLGK 194
>gi|57105752|ref|XP_543347.1| PREDICTED: similar to Peroxisomal membrane protein 2 (22 kDa
peroxisomal membrane protein) [Canis familiaris]
Length = 229
Score = 208 bits (529), Expect = 2e-52, Method: Composition-based stats.
Identities = 111/156 (71%), Positives = 124/156 (79%), Gaps = 1/156 (0%)
Query: 41 SGILSALGNFLAQMIEKKRKKEN-SRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIP 99
SGILSALGNFLAQMIEKKR+KEN S+ LDV GPLRYA+YGFFFTGPL+HFFY FMEHWIP
Sbjct: 74 SGILSALGNFLAQMIEKKREKENCSQKLDVSGPLRYAIYGFFFTGPLNHFFYLFMEHWIP 133
Query: 100 PEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGFWPALRMNWRVW 159
PEVPLAG +FAPA EG++ +AFA ++R FWPAL MNWRVW
Sbjct: 134 PEVPLAGVKRLLLDRLLFAPAFLLLFFLIMNFLEGRETAAFAVQIRRSFWPALCMNWRVW 193
Query: 160 TPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
TP+QFININYVPL+FRVLFANL +LFWY YLASLGK
Sbjct: 194 TPVQFININYVPLQFRVLFANLVSLFWYIYLASLGK 229
>gi|149756812|ref|XP_001493559.1| PREDICTED: similar to Peroxisomal membrane protein 2, 22kDa [Equus
caballus]
Length = 172
Score = 206 bits (523), Expect = 9e-52, Method: Composition-based stats.
Identities = 110/156 (70%), Positives = 124/156 (79%), Gaps = 1/156 (0%)
Query: 41 SGILSALGNFLAQMIEKKRKKEN-SRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIP 99
S +LSALGNFLAQ+ E+++KKEN S+ LDV GPLRYA+YGFFFTGPLSH FY F+EHWIP
Sbjct: 17 SAMLSALGNFLAQIFEQQQKKENCSQKLDVIGPLRYAIYGFFFTGPLSHHFYLFLEHWIP 76
Query: 100 PEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGFWPALRMNWRVW 159
PEVPLAG +FAPA EG+DA+AFAAKMR GFWPAL+MNWRVW
Sbjct: 77 PEVPLAGVKRLLLDRLLFAPAFLLVFFLVMNFLEGRDAAAFAAKMRRGFWPALQMNWRVW 136
Query: 160 TPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
TP+QFININYVPL+FRVLFANL ALFWY YLASL K
Sbjct: 137 TPVQFININYVPLQFRVLFANLVALFWYTYLASLRK 172
>gi|1172540|sp|P42925|PXMP2_MOUSE Peroxisomal membrane protein 2 (22 kDa peroxisomal membrane
protein)
gi|454833|gb|AAA39957.1| peroxisome membrane protein [Mus musculus]
Length = 194
Score = 191 bits (484), Expect = 3e-47, Method: Composition-based stats.
Identities = 105/160 (65%), Positives = 118/160 (73%), Gaps = 1/160 (0%)
Query: 36 TKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFME 95
TKA +SGILSALGN LAQ IEKK++K+ SR L+V G LRY VYG F TGPLSH+ Y FME
Sbjct: 36 TKAVSSGILSALGNLLAQTIEKKQRKD-SRLLEVSGLLRYLVYGLFVTGPLSHYLYLFME 94
Query: 96 HWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGFWPALRMN 155
+ +PPEVP A FAP EGK+ S F AKMR GFWPAL+MN
Sbjct: 95 YSVPPEVPWASVKRLLLDRLFFAPTFLLLFFFVMNLLEGKNVSVFVAKMRSGFWPALQMN 154
Query: 156 WRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
WR+WTPLQFININYVPL+FRVLFAN+AALFWYAYLASLGK
Sbjct: 155 WRMWTPLQFININYVPLQFRVLFANMAALFWYAYLASLGK 194
>gi|149634336|ref|XP_001509760.1| PREDICTED: similar to Peroxisomal membrane protein 2, 22kDa
[Ornithorhynchus anatinus]
Length = 194
Score = 189 bits (481), Expect = 6e-47, Method: Composition-based stats.
Identities = 104/161 (64%), Positives = 122/161 (75%), Gaps = 1/161 (0%)
Query: 36 TKAATSGILSALGNFLAQMIEKKRKKEN-SRSLDVGGPLRYAVYGFFFTGPLSHFFYFFM 94
TKA TSGILSALGNFLAQ+IEK+ KKE S+SL++ GPLRYA+YGF FTGPLSHFFY++M
Sbjct: 34 TKAVTSGILSALGNFLAQVIEKRGKKEKCSQSLELSGPLRYAIYGFLFTGPLSHFFYWYM 93
Query: 95 EHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGFWPALRM 154
E IPP VP A VFAP EG++ +AF+ KMR G+W AL+M
Sbjct: 94 EQLIPPAVPFAVVRRLLLDRLVFAPVFLLLFFFVMNLLEGQNMAAFSKKMRTGYWKALKM 153
Query: 155 NWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
NW+VWTP+QFININYVP++FRVLFANL ALFWYAYLASL K
Sbjct: 154 NWKVWTPIQFININYVPVQFRVLFANLVALFWYAYLASLRK 194
>gi|112421058|ref|NP_033019.2| peroxisomal membrane protein 2 [Mus musculus]
gi|10954089|gb|AAG25724.1|AF309644_1 22 kDa peroxisomal membrane protein PMP22 [Mus musculus]
gi|12833578|dbj|BAB22578.1| unnamed protein product [Mus musculus]
gi|37046832|gb|AAH57975.1| Peroxisomal membrane protein 2 [Mus musculus]
gi|148688081|gb|EDL20028.1| peroxisomal membrane protein 2, isoform CRA_a [Mus musculus]
Length = 193
Score = 189 bits (479), Expect = 1e-46, Method: Composition-based stats.
Identities = 103/160 (64%), Positives = 118/160 (73%), Gaps = 2/160 (1%)
Query: 36 TKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFME 95
TKA +SGILSALGN LAQ IEK++K +S++L+V G LRY VYG F TGPLSH+ Y FME
Sbjct: 36 TKAVSSGILSALGNLLAQTIEKRKK--DSQNLEVSGLLRYLVYGLFVTGPLSHYLYLFME 93
Query: 96 HWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGFWPALRMN 155
+ +PPEVP A FAP EGK+ S F AKMR GFWPAL+MN
Sbjct: 94 YSVPPEVPWASVKRLLLDRLFFAPTFLLLFFFVMNLLEGKNVSVFVAKMRSGFWPALQMN 153
Query: 156 WRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
WR+WTPLQFININYVPL+FRVLFAN+AALFWYAYLASLGK
Sbjct: 154 WRMWTPLQFININYVPLQFRVLFANMAALFWYAYLASLGK 193
>gi|119575216|gb|EAW54829.1| peroxisomal membrane protein 2, 22kDa, isoform CRA_b [Homo sapiens]
Length = 164
Score = 187 bits (474), Expect = 4e-46, Method: Composition-based stats.
Identities = 100/122 (81%), Positives = 100/122 (81%)
Query: 54 MIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIPPEVPLAGXXXXXXX 113
MIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIPPEVPLAG
Sbjct: 1 MIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIPPEVPLAGLRRLLLD 60
Query: 114 XXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGFWPALRMNWRVWTPLQFININYVPLK 173
VFAPA EGKDASAFAAKMRGGFWPALRMNWRVWTPLQFININYVPLK
Sbjct: 61 RLVFAPAFLMLFFLIMNFLEGKDASAFAAKMRGGFWPALRMNWRVWTPLQFININYVPLK 120
Query: 174 FR 175
R
Sbjct: 121 VR 122
>gi|126323846|ref|XP_001366379.1| PREDICTED: similar to Peroxisomal membrane protein 2, 22kDa
[Monodelphis domestica]
Length = 200
Score = 182 bits (463), Expect = 9e-45, Method: Composition-based stats.
Identities = 94/161 (58%), Positives = 121/161 (75%), Gaps = 1/161 (0%)
Query: 36 TKAATSGILSALGNFLAQMIEKKRKKEN-SRSLDVGGPLRYAVYGFFFTGPLSHFFYFFM 94
TK+ TSGILSA GNFL+Q+I+ +KK S++LD GPLRYA++GFFF+GPLSHFFY ++
Sbjct: 40 TKSVTSGILSAFGNFLSQIIKSVQKKGRWSQNLDPRGPLRYAIFGFFFSGPLSHFFYLYL 99
Query: 95 EHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGFWPALRM 154
+HWIP VP +G VFAPA EGK+ +AF+AK++ G+W AL+M
Sbjct: 100 DHWIPAAVPFSGVRRLLLDRLVFAPAFLLLFFFCMNLLEGKNLAAFSAKVKTGYWTALQM 159
Query: 155 NWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
NW++WTP+QFININY+PL+FRVLF N+ ALFWY YLASLGK
Sbjct: 160 NWKIWTPVQFININYIPLQFRVLFGNMVALFWYTYLASLGK 200
>gi|52219060|ref|NP_001004607.1| hypothetical protein LOC447868 [Danio rerio]
gi|125815924|ref|XP_001330954.1| PREDICTED: hypothetical protein [Danio rerio]
gi|51859403|gb|AAH81668.1| Zgc:92599 [Danio rerio]
gi|123227638|emb|CAM16312.1| novel protein similar to vertebrate peroxisomal membrane protein 2,
22kDa (PXMP2) [Danio rerio]
Length = 194
Score = 171 bits (432), Expect = 3e-41, Method: Composition-based stats.
Identities = 88/175 (50%), Positives = 118/175 (67%), Gaps = 3/175 (1%)
Query: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIE-KKRKKENS--RSLDVGGPLRYAVYGF 80
QYL L+ YP++TK+ TSGILSALGN L+Q++E +K KENS + + + GP+ +A+YG
Sbjct: 20 QYLSLLKKYPIITKSVTSGILSALGNLLSQVLEYQKNVKENSPKKKISILGPVHFAIYGL 79
Query: 81 FFTGPLSHFFYFFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAF 140
F TGP+SH+FY +E +P VP +FAPA EGK +
Sbjct: 80 FITGPVSHYFYHLLEVLLPTTVPYCLIKRLLLERLIFAPAFLLLFYVVMNALEGKTLADV 139
Query: 141 AAKMRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
K++ +WPA++MNW+VWTP QFININYVP++FRVLFAN+ ALFWYAYLAS+ K
Sbjct: 140 QNKLKTSYWPAMKMNWKVWTPFQFININYVPVQFRVLFANMVALFWYAYLASVRK 194
>gi|55742326|ref|NP_001006885.1| peroxisomal membrane protein 2, 22kDa [Xenopus tropicalis]
gi|50416665|gb|AAH77678.1| Peroxisomal membrane protein 2, 22kDa [Xenopus tropicalis]
Length = 193
Score = 167 bits (422), Expect = 4e-40, Method: Composition-based stats.
Identities = 86/161 (53%), Positives = 111/161 (68%), Gaps = 1/161 (0%)
Query: 33 PVLTKAATSGILSALGNFLAQMIEKKRKKE-NSRSLDVGGPLRYAVYGFFFTGPLSHFFY 91
PVLTKA TS ILSALGN L+Q I+K RK++ + +++D+ GPLR+AVYG FTGPLSH+FY
Sbjct: 30 PVLTKALTSAILSALGNILSQTIQKWRKEQKHPQNVDLRGPLRFAVYGLLFTGPLSHYFY 89
Query: 92 FFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGFWPA 151
+E +P PLAG + APA EGK+ + K++ +W A
Sbjct: 90 LLLEQLVPSSAPLAGLQRLLIERLIIAPAFLLLFFLVMNLLEGKNFTKLNQKLKSSYWQA 149
Query: 152 LRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLAS 192
L++NW+VWTP QFININYVP++FRVLFANL A FWYAYL+S
Sbjct: 150 LKLNWKVWTPFQFININYVPVQFRVLFANLVAFFWYAYLSS 190
>gi|148232453|ref|NP_001088759.1| hypothetical protein LOC496023 [Xenopus laevis]
gi|56270469|gb|AAH87416.1| LOC496023 protein [Xenopus laevis]
Length = 193
Score = 164 bits (416), Expect = 2e-39, Method: Composition-based stats.
Identities = 85/161 (52%), Positives = 110/161 (68%), Gaps = 1/161 (0%)
Query: 33 PVLTKAATSGILSALGNFLAQMIEKKRKKENS-RSLDVGGPLRYAVYGFFFTGPLSHFFY 91
PVLTKA TS ILSALGN L+Q I+K RK++ + +++D+ GP R+AVYG FTGPLSH+FY
Sbjct: 30 PVLTKALTSAILSALGNILSQTIQKWRKEQKAPQNVDLRGPFRFAVYGLLFTGPLSHYFY 89
Query: 92 FFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGFWPA 151
+E +P PLAG + APA EGK+ + K++ +W A
Sbjct: 90 LLLEQLVPSSAPLAGLQRLLIERLMIAPAFLLLFFLVMNLLEGKNLAKLNKKLKDHYWSA 149
Query: 152 LRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLAS 192
L++NW+VWTP QFININY+P++FRVLFANL A FWYAYLAS
Sbjct: 150 LKLNWKVWTPFQFININYIPVQFRVLFANLVAFFWYAYLAS 190
>gi|47226497|emb|CAG08513.1| unnamed protein product [Tetraodon nigroviridis]
Length = 175
Score = 157 bits (398), Expect = 2e-37, Method: Composition-based stats.
Identities = 88/174 (50%), Positives = 107/174 (61%), Gaps = 5/174 (2%)
Query: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPL--RYAVYGFF 81
QYL LR YP+LTK+ TSGIL+ALGN L+Q +E ++K N + GP RYA YG F
Sbjct: 5 QYLFLLRKYPILTKSVTSGILTALGNLLSQSLEARKKASNDA---ICGPAVARYAAYGLF 61
Query: 82 FTGPLSHFFYFFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFA 141
TGP+SH FY ME IP P FAP E K
Sbjct: 62 ITGPVSHCFYQLMEALIPATDPHCIIKRLLLDRLFFAPGFLLIFYLVMNVLELKGWKELE 121
Query: 142 AKMRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLASLGK 195
AK++G FW AL+MNW+VWTP QF+NIN+VP++FRVLFAN+ ALFWYAYLAS+ K
Sbjct: 122 AKLKGSFWTALKMNWKVWTPFQFVNINFVPVQFRVLFANVVALFWYAYLASVRK 175
>gi|156359662|ref|XP_001624885.1| predicted protein [Nematostella vectensis]
gi|156211690|gb|EDO32785.1| predicted protein [Nematostella vectensis]
Length = 200
Score = 119 bits (297), Expect = 1e-25, Method: Composition-based stats.
Identities = 59/169 (34%), Positives = 96/169 (56%), Gaps = 3/169 (1%)
Query: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFT 83
QY +L+ +P+LTK+ TS I S LG ++Q+ K+ +N + ++ +GF T
Sbjct: 25 QYSYYLQTHPILTKSITSAITSGLGQLVSQLAAKRATGQNINYRAIAA---FSGFGFLVT 81
Query: 84 GPLSHFFYFFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAK 143
GPL H+FY ++E ++P VP + +F+P EGK A+
Sbjct: 82 GPLVHYFYNYLEQFVPRGVPFSKAKKLFIDRLIFSPPFYLLFFYIVAIFEGKSNKEAIAR 141
Query: 144 MRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLAS 192
++ +W AL+M+ +VW +QF+N Y+P+++RVLFANL ALFW YL++
Sbjct: 142 IKANYWGALKMSLKVWPLVQFVNFTYIPVQYRVLFANLVALFWSIYLST 190
>gi|149063732|gb|EDM14055.1| peroxisomal membrane protein 2, isoform CRA_a [Rattus norvegicus]
Length = 145
Score = 117 bits (292), Expect = 5e-25, Method: Composition-based stats.
Identities = 64/96 (66%), Positives = 73/96 (76%), Gaps = 1/96 (1%)
Query: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFT 83
QYLLFL+ YPV+TKA +SGILSALGN LAQMIEKK+KK+ SRSL+V G LRY VYG F T
Sbjct: 24 QYLLFLKFYPVVTKAVSSGILSALGNLLAQMIEKKQKKD-SRSLEVSGLLRYLVYGLFVT 82
Query: 84 GPLSHFFYFFMEHWIPPEVPLAGXXXXXXXXXVFAP 119
GPLSH+ Y FME+W+PPEVP A FAP
Sbjct: 83 GPLSHYLYLFMEYWVPPEVPWARVKRLLLDRLFFAP 118
>gi|72124564|ref|XP_789205.1| PREDICTED: similar to peroxisomal membrane protein 2, 22kDa
[Strongylocentrotus purpuratus]
gi|115940766|ref|XP_001195583.1| PREDICTED: similar to peroxisomal membrane protein 2, 22kDa
[Strongylocentrotus purpuratus]
Length = 152
Score = 100 bits (248), Expect = 6e-20, Method: Composition-based stats.
Identities = 59/153 (38%), Positives = 82/153 (53%), Gaps = 5/153 (3%)
Query: 41 SGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFMEHWIPP 100
+G ++ +G+ +AQ R + S V +AV G FFTGPLSH+FY +++ P
Sbjct: 2 AGAIAGIGDIIAQ-----RLVDPSSPYTVRSTAAFAVLGTFFTGPLSHYFYAWLQKTFPG 56
Query: 101 EVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMRGGFWPALRMNWRVWT 160
+ VFAP EGK + K+R +W AL+MNWR+WT
Sbjct: 57 KDVPTSIKKILCDRLVFAPPYLLIFFYLLGIIEGKGHAVSVEKIRETYWIALKMNWRIWT 116
Query: 161 PLQFININYVPLKFRVLFANLAALFWYAYLASL 193
Q+ININYVPL+FRVLFA++ A W YLA +
Sbjct: 117 ISQYININYVPLQFRVLFASVIAFVWTIYLAVM 149
>gi|148688082|gb|EDL20029.1| peroxisomal membrane protein 2, isoform CRA_b [Mus musculus]
Length = 139
Score = 90.5 bits (223), Expect = 6e-17, Method: Composition-based stats.
Identities = 49/84 (58%), Positives = 59/84 (70%), Gaps = 2/84 (2%)
Query: 36 TKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGPLSHFFYFFME 95
TKA +SGILSALGN LAQ IEK++K +S++L+V G LRY VYG F TGPLSH+ Y FME
Sbjct: 36 TKAVSSGILSALGNLLAQTIEKRKK--DSQNLEVSGLLRYLVYGLFVTGPLSHYLYLFME 93
Query: 96 HWIPPEVPLAGXXXXXXXXXVFAP 119
+ +PPEVP A FAP
Sbjct: 94 YSVPPEVPWASVKRLLLDRLFFAP 117
>gi|66513493|ref|XP_623568.1| PREDICTED: similar to CG7970-PA [Apis mellifera]
Length = 186
Score = 86.3 bits (212), Expect = 1e-15, Method: Composition-based stats.
Identities = 60/166 (36%), Positives = 81/166 (48%), Gaps = 13/166 (7%)
Query: 28 FLRLY--PVLTKAATSGILSALGNFLAQMIEKKRKKENSRSLDVGGPLRYAVYGFFFTGP 85
F RLY PV TKA TS I++ LGNFL+Q I K N SL L +A++G F GP
Sbjct: 18 FERLYTSPVKTKAITSCIIATLGNFLSQKISGV-KHLNEDSL-----LAFALFGLIFGGP 71
Query: 86 LSHFFYFFMEHWIPPEVPLAGXXXXXXXXXVFAPAXXXXXXXXXXXXEGKDASAFAAKMR 145
L H+FY +++ ++ + L ++ P EG +M+
Sbjct: 72 LPHYFYTYIQLFVRNPLML-----LLVERCLYTPCYQALALYMLSLFEGNTHKDACKQMK 126
Query: 146 GGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLA 191
+WP + N + T LQFIN+ YVP RVL NL FW YLA
Sbjct: 127 SLYWPVIIANLKYLTLLQFINLKYVPPILRVLVVNLIGFFWAIYLA 172
>gi|76664098|emb|CAI59818.2| MPV17 protein [Nyctotherus ovalis]
Length = 191
Score = 84.0 bits (206), Expect = 5e-15, Method: Composition-based stats.
Identities = 54/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)
Query: 24 QYLLFLRLYPVLTKAATSGILSALGNFLAQMIEKKR--------KKENSRSLDVGGPLRY 75
+Y L+ YP+LTKA T GIL+ +F +Q IEK+ K E S+S D +R+
Sbjct: 6 KYTDLLKRYPLLTKAITGGILAFASDFTSQTIEKRTHVDTVGMLKIEGSQSFDYKRNIRF 65
Query: 76 AVYGFFFTGPLSHFFYFFMEHWIPPEVPLAGXXXXXXXXX---VFA-PAXXXXXXXXXXX 131
++ P+ H++ H +P P+ G +FA P
Sbjct: 66 GLFNLIINVPILHYY---TAHLLPKICPVTGVPTLLRKVAFDQIFAAPVFLTIFFGGLTL 122
Query: 132 XEGKDASAFAAKMRGGFWPALRMNWRVWTPLQFININYVPLKFRVLFANLAALFWYAYLA 191
E + A K R WP L+ NW +W + IN VP+ ++VLF+N+A+ W YL+
Sbjct: 123 CEFRGMQAAVDKCRERLWPTLKTNWMIWPLVNLINFGLVPIHYQVLFSNVASFGWGTYLS 182