BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= XP_822456.1__[Trypanosoma_brucei]
(471 letters)
Database: nr.pal
6,348,806 sequences; 2,166,943,470 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71746802|ref|XP_822456.1| hexokinase [Trypanosoma brucei... 931 0.0
gi|15626363|emb|CAC69958.1| hexokinase [Trypanosoma brucei] 929 0.0
gi|71746804|ref|XP_822457.1| hexokinase [Trypanosoma brucei... 909 0.0
gi|71655813|ref|XP_816463.1| hexokinase, putative [Trypanos... 668 0.0
gi|71413728|ref|XP_808992.1| hexokinase, putative [Trypanos... 666 0.0
gi|19703093|gb|AAL93565.1|AF488830_1 hexokinase [Trypanosom... 665 0.0
gi|154337016|ref|XP_001564741.1| hexokinase, putative [Leis... 598 e-169
gi|50261259|gb|AAT72300.1| hemoglobin receptor [Leishmania ... 586 e-165
gi|157868812|ref|XP_001682958.1| hexokinase, putative [Leis... 585 e-165
gi|146085727|ref|XP_001465336.1| hexokinase [Leishmania inf... 585 e-165
gi|146085723|ref|XP_001465335.1| hexokinase [Leishmania inf... 584 e-165
gi|157868810|ref|XP_001682957.1| hexokinase, putative [Leis... 584 e-165
gi|54292807|gb|AAV32455.1| hexokinase [Leishmania infantum] 564 e-159
gi|54292809|gb|AAV32456.1| hexokinase [Leishmania mexicana] 557 e-157
gi|56412257|gb|AAV88622.1| hexokinase [Leishmania donovani] 546 e-153
gi|54300692|gb|AAV32969.1| hexokinase [Leishmania tropica] 493 e-137
gi|71680940|gb|AAI00649.1| Hexokinase 3 [Rattus norvegicus]... 275 4e-72
gi|149039900|gb|EDL94016.1| hexokinase 3, isoform CRA_b [Ra... 275 8e-72
gi|11559937|ref|NP_071515.1| hexokinase 3 [Rattus norvegicu... 273 2e-71
gi|74150193|dbj|BAE24390.1| unnamed protein product [Mus mu... 271 1e-70
gi|74211734|dbj|BAE29220.1| unnamed protein product [Mus mu... 270 1e-70
gi|74200437|dbj|BAE37000.1| unnamed protein product [Mus mu... 270 1e-70
gi|84370288|ref|NP_001028417.1| hexokinase 3 [Mus musculus]... 270 1e-70
gi|73954004|ref|XP_546212.2| PREDICTED: similar to Hexokina... 270 2e-70
gi|115527510|gb|AAI17862.1| Hk3 protein [Mus musculus] 270 2e-70
gi|74140372|dbj|BAE42341.1| unnamed protein product [Mus mu... 269 4e-70
gi|149726625|ref|XP_001498596.1| PREDICTED: similar to Hexo... 269 4e-70
gi|74218150|dbj|BAE42045.1| unnamed protein product [Mus mu... 268 6e-70
gi|50307177|ref|XP_453567.1| HXK_KLULA [Kluyveromyces lacti... 268 6e-70
gi|11386886|sp|Q9SEK3|HXK1_SPIOL Hexokinase-1 (SoHxK1) >gi|... 268 7e-70
gi|149238644|ref|XP_001525198.1| hexokinase [Lodderomyces e... 268 8e-70
gi|74204817|dbj|BAE35470.1| unnamed protein product [Mus mu... 268 1e-69
gi|45198797|ref|NP_985826.1| AFR279Cp [Ashbya gossypii ATCC... 267 1e-69
gi|74204011|dbj|BAE29007.1| unnamed protein product [Mus mu... 267 1e-69
gi|47227723|emb|CAG09720.1| unnamed protein product [Tetrao... 267 1e-69
gi|109734501|gb|AAI17861.1| Hk3 protein [Mus musculus] 267 2e-69
gi|45383696|ref|NP_989543.1| hexokinase 2 [Gallus gallus] >... 266 2e-69
gi|313225|emb|CAA43855.1| hexakinase [Kluyveromyces lactis] 266 3e-69
gi|158255484|dbj|BAF83713.1| unnamed protein product [Homo ... 265 4e-69
gi|156151420|ref|NP_079406.3| hexokinase domain containing ... 265 4e-69
gi|47085787|ref|NP_998231.1| hexokinase 2 [Danio rerio] >gi... 265 6e-69
gi|55665501|emb|CAH71500.1| hexokinase domain containing 1 ... 265 6e-69
gi|15214423|gb|AAH12337.1| HKDC1 protein [Homo sapiens] 265 8e-69
gi|118092591|ref|XP_421579.2| PREDICTED: similar to Hexokin... 263 2e-68
gi|109079860|ref|XP_001086179.1| PREDICTED: hexokinase 3 [M... 263 2e-68
gi|126343367|ref|XP_001364147.1| PREDICTED: similar to Hexo... 261 6e-68
gi|68477224|ref|XP_717405.1| hexokinase II [Candida albican... 261 6e-68
gi|168016823|ref|XP_001760948.1| hexokinase protein HXK4 [P... 261 7e-68
gi|109089486|ref|XP_001110556.1| PREDICTED: similar to hexo... 261 8e-68
gi|39581300|emb|CAE72321.1| Hypothetical protein CBG19465 [... 261 8e-68
gi|15233457|ref|NP_194642.1| ATHXK1 (GLUCOSE INSENSITIVE 2)... 260 1e-67
gi|114603561|ref|XP_001137121.1| PREDICTED: hexokinase 3 is... 260 1e-67
gi|114603559|ref|XP_518124.2| PREDICTED: hexokinase 3 isofo... 260 2e-67
gi|18204272|gb|AAH21278.1| HKDC1 protein [Homo sapiens] 260 2e-67
gi|20380888|gb|AAH28129.1| Hexokinase 3 (white cell) [Homo ... 260 2e-67
gi|61369021|gb|AAX43272.1| hexokinase 3 [synthetic construct] 260 2e-67
gi|4504395|ref|NP_002106.1| hexokinase 3 [Homo sapiens] >gi... 260 2e-67
gi|150866927|ref|XP_001386689.2| Hexokinase [Pichia stipiti... 259 2e-67
gi|21703836|ref|NP_663394.1| hexokinase domain containing 1... 259 3e-67
gi|148230649|ref|NP_001090603.1| hypothetical protein LOC10... 259 3e-67
gi|125557582|gb|EAZ03118.1| hypothetical protein OsI_024350... 259 3e-67
gi|126352418|ref|NP_001075245.1| hexokinase II [Equus cabal... 259 4e-67
gi|587202|emb|CAA86511.1| Human hexokinase II cDNA [Homo sa... 259 4e-67
gi|119620009|gb|EAW99603.1| hexokinase 2, isoform CRA_b [Ho... 259 4e-67
gi|115439869|ref|NP_001044214.1| Os01g0742500 [Oryza sativa... 258 5e-67
gi|115471051|ref|NP_001059124.1| Os07g0197100 [Oryza sativa... 258 6e-67
gi|109103519|ref|XP_001111706.1| PREDICTED: similar to hexo... 258 7e-67
gi|45387409|gb|AAS60195.1| hexokinase 4a [Nicotiana tabacum] 258 7e-67
gi|18141293|gb|AAL60584.1|AF454962_1 hexokinase [Brassica o... 258 7e-67
gi|114578344|ref|XP_001162535.1| PREDICTED: hexokinase 2 is... 258 8e-67
gi|15553127|ref|NP_000180.2| hexokinase 2 [Homo sapiens] >g... 258 8e-67
gi|158261737|dbj|BAF83046.1| unnamed protein product [Homo ... 258 9e-67
gi|5804910|emb|CAA86476.2| hexokinase II [Homo sapiens] 257 1e-66
gi|119390703|pdb|2NZT|A Chain A, Crystal Structure Of Human... 257 1e-66
gi|45387411|gb|AAS60196.1| hexokinase 4b [Nicotiana tabacum] 257 1e-66
gi|155008468|gb|ABS89273.1| hexokinase 1b [Gadus morhua] 257 1e-66
gi|109103521|ref|XP_001111663.1| PREDICTED: similar to hexo... 257 1e-66
gi|114578346|ref|XP_001162408.1| PREDICTED: hexokinase 2 is... 257 1e-66
gi|68437695|ref|XP_702631.1| PREDICTED: hypothetical protei... 257 1e-66
gi|54606886|ref|NP_998417.1| hexokinase 1 [Danio rerio] >gi... 257 1e-66
gi|119193240|ref|XP_001247226.1| hexokinase [Coccidioides i... 257 1e-66
gi|73953327|ref|XP_546137.2| PREDICTED: similar to hexokina... 257 2e-66
gi|125553095|gb|EAY98804.1| hypothetical protein OsI_020037... 257 2e-66
gi|74219346|dbj|BAE26802.1| unnamed protein product [Mus mu... 257 2e-66
gi|171739|gb|AAA34699.1| hexokinase (HXK2) 256 2e-66
gi|126304047|ref|XP_001381777.1| PREDICTED: similar to hexo... 256 2e-66
gi|171735|gb|AAA34697.1| hexokinase P-II peptide >gi|224664... 256 3e-66
gi|7549765|ref|NP_036867.1| hexokinase 2 [Rattus norvegicus... 256 3e-66
gi|119903225|ref|XP_001255832.1| PREDICTED: similar to hexo... 256 3e-66
gi|6754206|ref|NP_034568.1| hexokinase 1 [Mus musculus] >gi... 256 3e-66
gi|30316354|sp|P17710|HXK1_MOUSE Hexokinase-1 (Hexokinase t... 256 3e-66
gi|109089478|ref|XP_001110396.1| PREDICTED: similar to hexo... 256 3e-66
gi|109089480|ref|XP_001110227.1| PREDICTED: similar to hexo... 256 3e-66
gi|74150648|dbj|BAE25472.1| unnamed protein product [Mus mu... 256 3e-66
gi|148700158|gb|EDL32105.1| hexokinase 1, isoform CRA_c [Mu... 256 4e-66
gi|7305143|ref|NP_038848.1| hexokinase 2 [Mus musculus] >gi... 256 4e-66
gi|149038694|gb|EDL92983.1| hexokinase 1, isoform CRA_d [Ra... 256 4e-66
gi|148700156|gb|EDL32103.1| hexokinase 1, isoform CRA_a [Mu... 256 4e-66
gi|148700161|gb|EDL32108.1| hexokinase 1, isoform CRA_f [Mu... 256 4e-66
gi|149038692|gb|EDL92981.1| hexokinase 1, isoform CRA_b [Ra... 256 4e-66
>gi|71746802|ref|XP_822456.1| hexokinase [Trypanosoma brucei TREU927]
gi|70832124|gb|EAN77628.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 931 bits (2407), Expect = 0.0, Method: Composition-based stats.
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
>gi|15626363|emb|CAC69958.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 929 bits (2400), Expect = 0.0, Method: Composition-based stats.
Identities = 470/471 (99%), Positives = 470/471 (99%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLF FIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFDFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
>gi|71746804|ref|XP_822457.1| hexokinase [Trypanosoma brucei TREU927]
gi|70832125|gb|EAN77629.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 909 bits (2350), Expect = 0.0, Method: Composition-based stats.
Identities = 460/471 (97%), Positives = 465/471 (98%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLF FIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFDFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTV T+ISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVATMISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPI+MESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPISMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAK GSG+GAA ISA+V + K
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKGGSGVGAALISAIVADGK 471
>gi|71655813|ref|XP_816463.1| hexokinase, putative [Trypanosoma cruzi strain CL Brener]
gi|70881594|gb|EAN94612.1| hexokinase, putative [Trypanosoma cruzi]
Length = 471
Score = 668 bits (1724), Expect = 0.0, Method: Composition-based stats.
Identities = 316/471 (67%), Positives = 385/471 (81%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MS RLNN+L+HI+++ D +T+R +K+ +A+A+L NQFT+ + ++Q+M Y+++EM+EGL
Sbjct: 1 MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHEMIEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGREST+RMLPSYVYK DP +ATGVFYALDLGGTNFRVLRV CKEG V D + F IP+
Sbjct: 61 EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL+G A DLFGFIA +VKK ME +APEDLNRTVPLGFTFSFP EQ V+ G LI+WTKG
Sbjct: 121 QALQGTAEDLFGFIAQSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDHGFLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FST+GV+G DV+ LLQ A R+ +KV VVALCNDTVGTLI++YF DP+ QVGVIIGTGSN
Sbjct: 181 FSTRGVEGKDVVELLQKALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE A AVTK+P+VAARG+ TPINME GNFDSKY+FVLP T +D +D + N+ Q
Sbjct: 241 ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNYQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EKM+SGMYLGEI+RR+I HL+ ++CLP+AL + + SFE++F GMISADRMPGLQF
Sbjct: 301 TQEKMVSGMYLGEISRRMIAHLAELHCLPSALASKMAKPWSFETKFMGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR Q++ VDV + DL +IRDVC LVRGRAAQ+SA FC APLVKT+ +GRAT+AIDG
Sbjct: 361 TRQVFQELFHVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEK PSFRR+LQ N+N ILGP CDV LA+DGSGIGAAFISA+VVNDK
Sbjct: 421 SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK 471
>gi|71413728|ref|XP_808992.1| hexokinase, putative [Trypanosoma cruzi strain CL Brener]
gi|70873304|gb|EAN87141.1| hexokinase, putative [Trypanosoma cruzi]
Length = 471
Score = 666 bits (1718), Expect = 0.0, Method: Composition-based stats.
Identities = 316/471 (67%), Positives = 385/471 (81%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MS RLNN+L+HI+++ D +T+R +K+ +A+A+L NQFT+ + ++Q+M Y+++EM+EGL
Sbjct: 1 MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHEMIEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGREST+RMLPSYVYK DP +ATGVFYALDLGGTNFRVLRV CKEG V D + F IP+
Sbjct: 61 EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL+G A DLFGFIA +VKK ME +APEDLNRTVPLGFTFSFP EQ V+ G LI+WTKG
Sbjct: 121 QALQGTAEDLFGFIAKSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDNGFLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FST+GV+G DV+ LLQ A R+ +KV VVALCNDTVGTLI++YF DP+ QVGVIIGTGSN
Sbjct: 181 FSTRGVEGKDVVELLQNALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE A AVTK+P+VAARG+ TPINME GNFDSKY+FVLP T +D +D + N+ Q
Sbjct: 241 ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNYQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EKM+SGMYLGEI+RR+I HL+ + CLP+AL + + SFE++F GMISADRMPGLQF
Sbjct: 301 TQEKMVSGMYLGEISRRMIAHLAELRCLPSALASKMAKPWSFETKFMGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR +Q++ VDV + DL +IRDVC LVRGRAAQ+SA FC APLVKT+ +GRAT+AIDG
Sbjct: 361 TRQVLQELFHVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEK PSFRR+LQ N+N ILGP CDV LA+DGSGIGAAFISA+VVNDK
Sbjct: 421 SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK 471
>gi|19703093|gb|AAL93565.1|AF488830_1 hexokinase [Trypanosoma cruzi]
gi|19262944|emb|CAD26835.1| hexokinase [Trypanosoma cruzi]
Length = 471
Score = 665 bits (1716), Expect = 0.0, Method: Composition-based stats.
Identities = 315/471 (66%), Positives = 385/471 (81%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MS RLNN+L+HI+++ D +T+R +K+ +A+A+L NQFT+ + ++Q+M Y++++M+EGL
Sbjct: 1 MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHQMIEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGREST+RMLPSYVYK DP +ATGVFYALDLGGTNFRVLRV CKEG V D + F IP+
Sbjct: 61 EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL+G A DLFGFIA +VKK ME +APEDLNRTVPLGFTFSFP EQ V+ G LI+WTKG
Sbjct: 121 QALQGTAEDLFGFIAQSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDHGFLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FST+GV+G DV+ LLQ A R+ +KV VVALCNDTVGTLI++YF DP+ QVGVIIGTGSN
Sbjct: 181 FSTRGVEGKDVVELLQKALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE A AVTK+P+VAARG+ TPINME GNFDSKY+FVLP T +D +D + N+ Q
Sbjct: 241 ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNFQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EKM+SGMYLGEI+RR+I HL+ ++CLP+AL + + SFE++F GMISADRMPGLQF
Sbjct: 301 TQEKMVSGMYLGEISRRMIAHLAELHCLPSALASKMAKPWSFETKFMGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR Q++ VDV + DL +IRDVC LVRGRAAQ+SA FC APLVKT+ +GRAT+AIDG
Sbjct: 361 TRQVFQELFQVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEK PSFRR+LQ N+N ILGP CDV LA+DGSGIGAAFISA+VVNDK
Sbjct: 421 SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK 471
>gi|154337016|ref|XP_001564741.1| hexokinase, putative [Leishmania braziliensis MHOM/BR/75/M2904]
gi|134061779|emb|CAM38811.1| hexokinase, putative [Leishmania braziliensis]
Length = 471
Score = 598 bits (1543), Expect = e-169, Method: Composition-based stats.
Identities = 286/471 (60%), Positives = 367/471 (77%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN++ H++I+ +D E +R +K+ +A+A+L+ QFTM+ E M+Q+ Y++YEMVEGL
Sbjct: 1 MASRVNNLMNHLAIRDSDSEEMRYIKQRLALASLSTQFTMASEKMKQLTMYMVYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPSYVY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D S F IPK
Sbjct: 61 EGRPSTVRMLPSYVYTSDPAKATGVYYALDLGGTNFRVLRVSLRSGKVDDRIDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL GN+ +LF FIA +VKK M APEDL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALTGNSANLFDFIAQSVKKMMSENAPEDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQ + R+ + VNVVALCNDTVGTL++ YF D QVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQGSLRRMHINVNVVALCNDTVGTLVARYFVDTNAQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV ARG+A+TPINME GNFDSKY++ LPTT +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVCARGNAVTPINMECGNFDSKYKYALPTTVYDDEMDAITPNRDHQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L LG +FES+ GM++AD+MPGLQF
Sbjct: 301 RQEKIVSGMYLGEISRRMIVHLAQLGCLPRDLVDGLGKPWAFESKHMGMVAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I++V GV+V + DL IR++C LVR RAAQ +A AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRVAGVNVTDVADLHTIREICCLVRNRAAQQAAVLSAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK+PSF+R+ Q+ I ILGP + + VL KDGSG+GAA I A+ N K
Sbjct: 421 SVYEKVPSFQRLYQECITGILGPTSNAKVVLQKDGSGVGAAMICALAANQK 471
>gi|50261259|gb|AAT72300.1| hemoglobin receptor [Leishmania donovani]
Length = 471
Score = 586 bits (1511), Expect = e-165, Method: Composition-based stats.
Identities = 291/471 (61%), Positives = 369/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+++ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MATRVNNLLSHIALRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVDV + DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDVTDMSDLHTIRETCCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL KDGSG+GAA I A+ VN K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQKDGSGVGAAMICALAVNKK 471
>gi|157868812|ref|XP_001682958.1| hexokinase, putative [Leishmania major]
gi|68223841|emb|CAJ03835.1| hexokinase, putative [Leishmania major]
Length = 471
Score = 585 bits (1509), Expect = e-165, Method: Composition-based stats.
Identities = 291/471 (61%), Positives = 369/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MAARVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVD+ I DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDMADISDLHTIRETCCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL +DGSG+GAA I A+ VN K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQRDGSGVGAAMICALAVNTK 471
>gi|146085727|ref|XP_001465336.1| hexokinase [Leishmania infantum JPCM5]
gi|134069434|emb|CAM67757.1| hexokinase, putative [Leishmania infantum]
Length = 471
Score = 585 bits (1509), Expect = e-165, Method: Composition-based stats.
Identities = 291/471 (61%), Positives = 368/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MATRVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVDV + DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDVTDMSDLHTIREACCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL KDGSG+GAA I A+ N K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQKDGSGVGAAMICALAANKK 471
>gi|146085723|ref|XP_001465335.1| hexokinase [Leishmania infantum JPCM5]
gi|134069433|emb|CAM67756.1| hexokinase, putative [Leishmania infantum]
Length = 471
Score = 584 bits (1506), Expect = e-165, Method: Composition-based stats.
Identities = 290/471 (61%), Positives = 368/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MATRVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVDV + DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDVTDMSDLHTIREACCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL +DGSG+GAA I A+ N K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQRDGSGVGAAMICALAANKK 471
>gi|157868810|ref|XP_001682957.1| hexokinase, putative [Leishmania major]
gi|54292805|gb|AAV32454.1| hexokinase [Leishmania major]
gi|68223840|emb|CAJ03833.1| hexokinase, putative [Leishmania major]
Length = 471
Score = 584 bits (1505), Expect = e-165, Method: Composition-based stats.
Identities = 290/471 (61%), Positives = 368/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MAARVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVD+ I DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDMADISDLHTIRETCCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL +DGSG+GAA I A+ N K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQRDGSGVGAAMICALAANTK 471
>gi|54292807|gb|AAV32455.1| hexokinase [Leishmania infantum]
Length = 451
Score = 564 bits (1453), Expect = e-159, Method: Composition-based stats.
Identities = 281/449 (62%), Positives = 352/449 (78%)
Query: 18 DGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKA 77
D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGLEGR STVRMLPS+VY +
Sbjct: 1 DSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGLEGRPSTVRMLPSFVYTS 60
Query: 78 DPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASN 137
DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK AL G+ATDLF FIA +
Sbjct: 61 DPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPKSALVGDATDLFDFIAQS 120
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKGFSTK V+GNDV+ LLQA
Sbjct: 121 VKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKGFSTKNVEGNDVVELLQA 180
Query: 198 AFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVA 257
+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSNACYFE ASAVTKDPAV+
Sbjct: 181 SLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSNACYFERASAVTKDPAVS 240
Query: 258 ARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARR 317
ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q EK++SGMYLGEI+RR
Sbjct: 241 ARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQRQEKLVSGMYLGEISRR 300
Query: 318 VIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQFTR I+++ GVDV +
Sbjct: 301 LIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQFTRELIKRIAGVDVTDMS 360
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNI 437
DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DGSV+EK PSF+R+ Q+ I
Sbjct: 361 DLHTIREACCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDGSVYEKTPSFQRLYQECI 420
Query: 438 NRILGPECDVRAVLAKDGSGIGAAFISAM 466
ILG +V+ VL KDGSG+GAA I A+
Sbjct: 421 TSILGSTSNVKVVLQKDGSGVGAAMICAL 449
>gi|54292809|gb|AAV32456.1| hexokinase [Leishmania mexicana]
Length = 451
Score = 557 bits (1436), Expect = e-157, Method: Composition-based stats.
Identities = 278/449 (61%), Positives = 349/449 (77%)
Query: 18 DGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKA 77
D E +R + + +A+A+L QFTMS E M+Q+ Y+++EMVEGLEGR STVRMLPS+VY +
Sbjct: 1 DSEEMRYITQRLALASLATQFTMSPEKMKQLTMYMIHEMVEGLEGRPSTVRMLPSFVYTS 60
Query: 78 DPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASN 137
DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK AL G+ATDLF FIA +
Sbjct: 61 DPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPKSALVGDATDLFDFIAQS 120
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
VKK M APEDL + VPLGFTFSFPV+Q VN+G+LI+WTKGFSTK V+G+DV+ LLQA
Sbjct: 121 VKKMMSENAPEDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKGFSTKNVEGSDVVELLQA 180
Query: 198 AFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVA 257
+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSNACYFE ASAVTKDPAV+
Sbjct: 181 SLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSNACYFERASAVTKDPAVS 240
Query: 258 ARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARR 317
ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q EK++SGMYLGEI+RR
Sbjct: 241 ARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQRQEKLVSGMYLGEISRR 300
Query: 318 VIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+IVHL+ + CLP L L +FES+ GM++AD+MPGLQFTR I++V GVDV
Sbjct: 301 LIVHLAHLGCLPRGLVDGLCKPWAFESKHMGMVAADQMPGLQFTRELIKRVAGVDVTDTS 360
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNI 437
DL IR+ C LVR RAAQ + F AP++KT+TQG AT+A+DGSV+EK PSF+R+ Q+ I
Sbjct: 361 DLHTIREACCLVRNRAAQQGSVFTAAPMLKTRTQGLATVAVDGSVYEKTPSFQRLYQECI 420
Query: 438 NRILGPECDVRAVLAKDGSGIGAAFISAM 466
ILG + + VL KDGSG+GAA I A+
Sbjct: 421 TSILGSTSNAKVVLQKDGSGVGAAMICAL 449
>gi|56412257|gb|AAV88622.1| hexokinase [Leishmania donovani]
Length = 434
Score = 546 bits (1406), Expect = e-153, Method: Composition-based stats.
Identities = 271/434 (62%), Positives = 341/434 (78%)
Query: 18 DGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKA 77
D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGLEGR STVRMLPS+VY +
Sbjct: 1 DSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGLEGRPSTVRMLPSFVYTS 60
Query: 78 DPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASN 137
DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK AL G+ATDLF FIA +
Sbjct: 61 DPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPKSALVGDATDLFDFIAQS 120
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKGFSTK V+GNDV+ LLQA
Sbjct: 121 VKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKGFSTKNVEGNDVVELLQA 180
Query: 198 AFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVA 257
+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSNACYFE ASAVTKDPAV+
Sbjct: 181 SLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSNACYFERASAVTKDPAVS 240
Query: 258 ARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARR 317
ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q EK++SGMYLGEI+RR
Sbjct: 241 ARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQRQEKLVSGMYLGEISRR 300
Query: 318 VIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+IVHL+ + CLP+ L L +FES+ GMI+AD+MPGLQFTR I+++ GVDV +
Sbjct: 301 LIVHLAQLGCLPSGLVDGLCRPWAFESKHMGMIAADQMPGLQFTRELIKRIAGVDVTDMS 360
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNI 437
DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DGSV+EK PSF+R+ Q+ I
Sbjct: 361 DLHTIRETCCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDGSVYEKTPSFQRLYQECI 420
Query: 438 NRILGPECDVRAVL 451
ILG +V+ VL
Sbjct: 421 TSILGSTSNVKVVL 434
>gi|54300692|gb|AAV32969.1| hexokinase [Leishmania tropica]
Length = 387
Score = 493 bits (1269), Expect = e-137, Method: Composition-based stats.
Identities = 245/387 (63%), Positives = 303/387 (78%)
Query: 18 DGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKA 77
D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGLEGR STVRMLPS+VY +
Sbjct: 1 DSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGLEGRPSTVRMLPSFVYTS 60
Query: 78 DPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASN 137
DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK AL G+ATDLF FIA +
Sbjct: 61 DPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPKSALVGDATDLFDFIAQS 120
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKGFSTK V+GNDV+ LLQA
Sbjct: 121 VKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKGFSTKNVEGNDVVELLQA 180
Query: 198 AFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVA 257
+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSNACYFE ASAVTKDPAV+
Sbjct: 181 SLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSNACYFERASAVTKDPAVS 240
Query: 258 ARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARR 317
ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q EK++SGMYLGEI+RR
Sbjct: 241 ARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQRQEKLVSGMYLGEISRR 300
Query: 318 VIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQFTR I+++ GVDV +
Sbjct: 301 LIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQFTRELIKRIAGVDVTDMS 360
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAP 404
DL IR+ C LVR RAAQ A F AP
Sbjct: 361 DLHTIRETCCLVRNRAAQQGAVFAAAP 387
>gi|71680940|gb|AAI00649.1| Hexokinase 3 [Rattus norvegicus]
gi|149039899|gb|EDL94015.1| hexokinase 3, isoform CRA_a [Rattus norvegicus]
Length = 924
Score = 275 bits (704), Expect = 4e-72, Method: Composition-based stats.
Identities = 162/436 (37%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +S+E + + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 490 FQLSLEQLTAVQAQMREAMIRGLQGESSSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 549
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + + IP+Y +G+ LF I + + + +++PLG
Sbjct: 550 VLLVRVAEGSV-QITNQVYSIPEYVAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 606
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 607 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 666
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S INME G F
Sbjct: 667 GTMMSCGYDDPCCEMGLIVGTGTNACYMEELRNVASVPG----DSGHMCINMEWGAFGDD 722
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+ T FD +D AS+N G+Q EKMISGMYLGEI R +++HL+S+ L +T
Sbjct: 723 GSLSMLGTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQKTQC 782
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 783 LQTRDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 839
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F R++ + R L P+C V +
Sbjct: 840 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSVTV-RKLAPQCTVTFL 898
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 899 QSEDGSGKGAALVTAV 914
Score = 216 bits (550), Expect = 3e-54, Method: Composition-based stats.
Identities = 157/445 (35%), Positives = 232/445 (52%), Gaps = 26/445 (5%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF +++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 39 QFKVTMTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 98
Query: 93 -GTNFRVLRV---ACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPE 148
G + RVL V KE +V ++ + F IP+ + G LF F A + + ++ E
Sbjct: 99 TGASLRVLWVTLTGTKEHSV-ETRSQEFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE 157
Query: 149 DLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVN 207
N+ + LGF FSFP QT +++ LI WTKGF GV+G DV+ LL+ A R + ++
Sbjct: 158 --NQGLKLGFNFSFPCHQTGLDKSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYNID 215
Query: 208 VVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPIN 267
VVA+ NDTVGT++ +VG+I+ TG+NACY E A V A T ++
Sbjct: 216 VVAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVS 271
Query: 268 MESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINC 327
+E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHLS
Sbjct: 272 IEWGSFYDEEALGPVLTTFDDALDHESLVPGAQRFEKMIGGLYLGELVRLVLVHLSQHGV 331
Query: 328 LPAALQT-ALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVC 386
L + AL ++ S + D G+ + +Q + G+ Q+ D +++ VC
Sbjct: 332 LFGGCASPALLSQNSILLEHVAKME-DPATGIAHVHTVLQGL-GLSPQA-SDAELVQRVC 388
Query: 387 RLVRGRAAQLSASFCCAPLVKTQTQGR-----ATIAIDGSVFEKIPSFRRVLQDNINRIL 441
V RAAQL AS A L + Q +A G VFE P F +L++ + +L
Sbjct: 389 MAVCTRAAQLCASALAAVLSRLQHSREQQTLHVAVATGGRVFEWHPRFLCILKETV-MLL 447
Query: 442 GPECDVRAVLAKDGSGIGAAFISAM 466
PECDV + + DG G G A ++A+
Sbjct: 448 APECDVSFIPSVDGGGRGVAMVTAV 472
>gi|149039900|gb|EDL94016.1| hexokinase 3, isoform CRA_b [Rattus norvegicus]
Length = 706
Score = 275 bits (702), Expect = 8e-72, Method: Composition-based stats.
Identities = 162/436 (37%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +S+E + + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 272 FQLSLEQLTAVQAQMREAMIRGLQGESSSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 331
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + + IP+Y +G+ LF I + + + +++PLG
Sbjct: 332 VLLVRVAEGSV-QITNQVYSIPEYVAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 388
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 389 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 448
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S INME G F
Sbjct: 449 GTMMSCGYDDPCCEMGLIVGTGTNACYMEELRNVASVPG----DSGHMCINMEWGAFGDD 504
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+ T FD +D AS+N G+Q EKMISGMYLGEI R +++HL+S+ L +T
Sbjct: 505 GSLSMLGTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQKTQC 564
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 565 LQTRDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 621
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F R++ + R L P+C V +
Sbjct: 622 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSVTV-RKLAPQCTVTFL 680
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 681 QSEDGSGKGAALVTAV 696
Score = 116 bits (290), Expect = 4e-24, Method: Composition-based stats.
Identities = 90/263 (34%), Positives = 127/263 (48%), Gaps = 16/263 (6%)
Query: 211 LCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMES 270
+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++E
Sbjct: 1 MVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSIEW 56
Query: 271 GNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL-- 328
G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHLS L
Sbjct: 57 GSFYDEEALGPVLTTFDDALDHESLVPGAQRFEKMIGGLYLGELVRLVLVHLSQHGVLFG 116
Query: 329 PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRL 388
A L A M D G+ + +Q + G+ Q+ D +++ VC
Sbjct: 117 GCASPALLSQNSILLEHVAKM--EDPATGIAHVHTVLQGL-GLSPQA-SDAELVQRVCMA 172
Query: 389 VRGRAAQLSASFCCAPLVKTQTQGR-----ATIAIDGSVFEKIPSFRRVLQDNINRILGP 443
V RAAQL AS A L + Q +A G VFE P F +L++ + +L P
Sbjct: 173 VCTRAAQLCASALAAVLSRLQHSREQQTLHVAVATGGRVFEWHPRFLCILKETV-MLLAP 231
Query: 444 ECDVRAVLAKDGSGIGAAFISAM 466
ECDV + + DG G G A ++A+
Sbjct: 232 ECDVSFIPSVDGGGRGVAMVTAV 254
>gi|11559937|ref|NP_071515.1| hexokinase 3 [Rattus norvegicus]
gi|123896|sp|P27926|HXK3_RAT Hexokinase-3 (Hexokinase type III) (HK III)
gi|1658068|gb|AAB18253.1| hexokinase type III [Rattus norvegicus]
Length = 924
Score = 273 bits (699), Expect = 2e-71, Method: Composition-based stats.
Identities = 161/434 (37%), Positives = 253/434 (58%), Gaps = 18/434 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +S+E + + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 490 FQLSLEQLTAVQAQMREAMIRGLQGESSSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 549
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + + IP+Y +G+ LF I + + + +++PLG
Sbjct: 550 VLLVRVAEGSV-QITNQVYSIPEYVAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 606
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 607 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 666
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S INME G F
Sbjct: 667 GTMMSCGYDDPCCEMGLIVGTGTNACYMEELRNVASVPG----DSGHMCINMEWGAFGDD 722
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+ T FD +D AS+N G+Q EKMISGMYLGEI R +++HL+S+ L +T
Sbjct: 723 GSLSMLGTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQKTQC 782
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 783 LQTRDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 839
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F R++ + R L P+C V +
Sbjct: 840 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSVTV-RKLAPQCTVTFL 898
Query: 451 LAKDGSGIGAAFIS 464
++DGSG GAA ++
Sbjct: 899 QSEDGSGKGAALVT 912
Score = 216 bits (550), Expect = 3e-54, Method: Composition-based stats.
Identities = 157/445 (35%), Positives = 232/445 (52%), Gaps = 26/445 (5%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF +++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 39 QFKVTMTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 98
Query: 93 -GTNFRVLRV---ACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPE 148
G + RVL V KE +V ++ + F IP+ + G LF F A + + ++ E
Sbjct: 99 TGASLRVLWVTLTGTKEHSV-ETRSQEFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE 157
Query: 149 DLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVN 207
N+ + LGF FSFP QT +++ LI WTKGF GV+G DV+ LL+ A R + ++
Sbjct: 158 --NQGLKLGFNFSFPCHQTGLDKSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYNID 215
Query: 208 VVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPIN 267
VVA+ NDTVGT++ +VG+I+ TG+NACY E A V A T ++
Sbjct: 216 VVAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVS 271
Query: 268 MESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINC 327
+E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHLS
Sbjct: 272 IEWGSFYDEEALGPVLTTFDDALDHESLVPGAQRFEKMIGGLYLGELVRLVLVHLSQHGV 331
Query: 328 LPAALQT-ALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVC 386
L + AL ++ S + D G+ + +Q + G+ Q+ D +++ VC
Sbjct: 332 LFGGCASPALLSQNSILLEHVAKME-DPATGIAHVHTVLQGL-GLSPQA-SDAELVQRVC 388
Query: 387 RLVRGRAAQLSASFCCAPLVKTQTQGR-----ATIAIDGSVFEKIPSFRRVLQDNINRIL 441
V RAAQL AS A L + Q +A G VFE P F +L++ + +L
Sbjct: 389 MAVCTRAAQLCASALAAVLSRLQHSREQQTLHVAVATGGRVFEWHPRFLCILKETV-MLL 447
Query: 442 GPECDVRAVLAKDGSGIGAAFISAM 466
PECDV + + DG G G A ++A+
Sbjct: 448 APECDVSFIPSVDGGGRGVAMVTAV 472
>gi|74150193|dbj|BAE24390.1| unnamed protein product [Mus musculus]
gi|74201193|dbj|BAE37444.1| unnamed protein product [Mus musculus]
Length = 922
Score = 271 bits (692), Expect = 1e-70, Method: Composition-based stats.
Identities = 160/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E M + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQMTVVQAQMRVAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 897 QSEDGSGKGAALVTAV 912
Score = 198 bits (504), Expect = 6e-49, Method: Composition-based stats.
Identities = 156/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ + +L P CDV + + DG G G A ++A+
Sbjct: 437 ILKETVT-LLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>gi|74211734|dbj|BAE29220.1| unnamed protein product [Mus musculus]
Length = 922
Score = 270 bits (691), Expect = 1e-70, Method: Composition-based stats.
Identities = 160/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E M + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQMTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 897 QSEDGSGKGAALVTAV 912
Score = 198 bits (504), Expect = 6e-49, Method: Composition-based stats.
Identities = 156/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQCVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ + +L P CDV + + DG G G A ++A+
Sbjct: 437 ILEETVT-LLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>gi|74200437|dbj|BAE37000.1| unnamed protein product [Mus musculus]
Length = 922
Score = 270 bits (691), Expect = 1e-70, Method: Composition-based stats.
Identities = 160/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E M + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQMTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 897 QSEDGSGKGAALVTAV 912
Score = 197 bits (501), Expect = 1e-48, Method: Composition-based stats.
Identities = 155/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ + R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDSIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ + +L P CDV + + DG G G A ++A+
Sbjct: 437 ILKETVT-LLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>gi|84370288|ref|NP_001028417.1| hexokinase 3 [Mus musculus]
gi|83288243|sp|Q3TRM8|HXK3_MOUSE Hexokinase-3 (Hexokinase type III) (HK III)
gi|74143046|dbj|BAE42538.1| unnamed protein product [Mus musculus]
gi|74185633|dbj|BAE32706.1| unnamed protein product [Mus musculus]
Length = 922
Score = 270 bits (691), Expect = 1e-70, Method: Composition-based stats.
Identities = 160/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E M + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQMTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 897 QSEDGSGKGAALVTAV 912
Score = 198 bits (504), Expect = 6e-49, Method: Composition-based stats.
Identities = 156/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ + +L P CDV + + DG G G A ++A+
Sbjct: 437 ILKETVT-LLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>gi|73954004|ref|XP_546212.2| PREDICTED: similar to Hexokinase type III (HK III) [Canis
familiaris]
Length = 957
Score = 270 bits (690), Expect = 2e-70, Method: Composition-based stats.
Identities = 165/437 (37%), Positives = 252/437 (57%), Gaps = 20/437 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F ++ E + + + MV+GL G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 519 FQLNHEQLAAVQAQMREAMVKGLRGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 578
Query: 98 VLRV-ACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPL 156
VL V EG V + + IP+ +G+ LF I + + + +++PL
Sbjct: 579 VLLVRVTAEG--VKITNQIYSIPENVAQGSGQQLFDHIVDCIVDFQQKQGLS--GQSLPL 634
Query: 157 GFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDT 215
GFTFSFP Q +++G+L+ WTKGFS +G D++ LL+ A GR ++++NVVA+ NDT
Sbjct: 635 GFTFSFPCRQLGLDQGILLNWTKGFSASDCEGQDIVCLLREAIGRRQAVELNVVAIVNDT 694
Query: 216 VGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDS 275
VGT++S ++DP +VG+I+GTG+NACY E V A A S INME G F
Sbjct: 695 VGTMMSCGYEDPRCEVGLIVGTGTNACYMEELRNV----AAVAGDSGQMCINMEWGAFGD 750
Query: 276 KYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQTA 335
L T FD +D AS+N G+Q+ EKMISGMYLGEI R +++HL+S+ L QT
Sbjct: 751 DGSLGLLRTCFDASVDQASINPGKQSFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQTQ 810
Query: 336 -LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAA 394
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAA
Sbjct: 811 RLQTRDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLSLTS-DDALMVLEVCQAVSQRAA 867
Query: 395 QLSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRA 449
QL + A + K + + +I +DG++++ P F ++ + R L P C V
Sbjct: 868 QLCGAGVAAVVEKIRENRGLEELTVSIGVDGTLYKLHPHFSSLVAATV-RELAPRCVVTF 926
Query: 450 VLAKDGSGIGAAFISAM 466
+ ++DGSG GAA ++A+
Sbjct: 927 LQSEDGSGKGAALVTAV 943
Score = 192 bits (487), Expect = 6e-47, Method: Composition-based stats.
Identities = 157/444 (35%), Positives = 229/444 (51%), Gaps = 24/444 (5%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L G+ S VRMLP+YV G F L+LG
Sbjct: 68 QFKVTGTQLQQIQASLLDSMEQALGGQASPASAVRMLPTYVGSIPHGTEQGDFVVLELGA 127
Query: 93 -GTNFRVLRVAC--KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V G ++ + F IP + G LF F A + + ++ A
Sbjct: 128 TGASLRVLWVTLMGTGGHRMEPRSQEFVIPPEVMLGPGQQLFDFAAHCLSEFLD--ALPV 185
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
+ + LGF+FSFP QT ++R LI WTKGF GV+G+DV+ LL+ A R + ++V
Sbjct: 186 GKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGHDVVQLLRDAIKRHGAYNIDV 245
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+++ TG+NACY E A V AV +++
Sbjct: 246 VAVVNDTVGTMMGCEPGVGPCEVGLVVDTGTNACYMEEARHV----AVLDEDRGRVCVSV 301
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F T FD +D SLN G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 302 EWGSFGDDGVLGPMLTIFDHALDRESLNPGAQRFEKMIGGLYLGELVRLVLVHLAQRGVL 361
Query: 329 PAALQT-ALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCR 387
+ AL +RGS + D G + +Q + G++V + D+ +++ VC
Sbjct: 362 FGGCTSPALLSRGSILLEHVAEME-DPWAGAARVHALLQDL-GLNVGA-SDVELVQYVCA 418
Query: 388 LVRGRAAQLSASFCCAPLVKTQTQGRATI-----AIDGSVFEKIPSFRRVLQDNINRILG 442
V RAA+L A+ A L + Q I A G VFE+ PSF +LQ+ + +L
Sbjct: 419 AVFTRAARLCAAALAAVLSRLQHSREQQILQIAVATGGRVFEQHPSFLSILQETV-MLLT 477
Query: 443 PECDVRAVLAKDGSGIGAAFISAM 466
PECDV + + DG G G A ++A+
Sbjct: 478 PECDVSFIPSVDGGGRGVAMVTAV 501
>gi|115527510|gb|AAI17862.1| Hk3 protein [Mus musculus]
Length = 877
Score = 270 bits (689), Expect = 2e-70, Method: Composition-based stats.
Identities = 159/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E + + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 443 FQLTLEQLTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 502
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 503 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 559
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 560 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 619
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 620 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 675
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 676 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 735
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 736 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 792
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 793 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 851
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 852 QSEDGSGKGAALVTAV 867
Score = 175 bits (444), Expect = 6e-42, Method: Composition-based stats.
Identities = 145/426 (34%), Positives = 214/426 (50%), Gaps = 47/426 (11%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P RR
Sbjct: 377 SDAELVQCVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHP--RR 434
Query: 432 VLQDNI 437
+L++ +
Sbjct: 435 ILEETL 440