BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= XP_822509__[Trypanosoma_brucei]
         (318 letters)

Database: nr.pal 
           6,348,806 sequences; 2,166,943,470 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71746908|ref|XP_822509.1|  mitochondrial malate dehydroge...   585   e-165
gi|2605782|gb|AAC27101.1|  malate dehydrogenase [Trypanosoma...   583   e-165
gi|71664243|ref|XP_819104.1|  malate dehydrogenase, putative...   437   e-121
gi|71414199|ref|XP_809210.1|  mitochondrial malate dehydroge...   415   e-114
gi|157875425|ref|XP_001686104.1|  malate dehydrogenase [Leis...   379   e-103
gi|146098508|ref|XP_001468402.1|  malate dehydrogenase [Leis...   375   e-102
gi|154336109|ref|XP_001564290.1|  malate dehydrogenase [Leis...   372   e-101
gi|154336105|ref|XP_001564288.1|  malate dehydrogenase, puta...   367   e-100
gi|146098517|ref|XP_001468404.1|  malate dehydrogenase [Leis...   358   4e-97
gi|157875429|ref|XP_001686106.1|  malate dehydrogenase, puta...   357   7e-97
gi|58269764|ref|XP_572038.1|  malate dehydrogenase [Cryptoco...   317   5e-85
gi|169865690|ref|XP_001839443.1|  hypothetical protein CC1G_...   314   6e-84
gi|157118108|ref|XP_001659012.1|  malate dehydrogenase [Aede...   312   2e-83
gi|4029338|emb|CAA76361.1|  malate dehydrogenase [Piromyces ...   311   3e-83
gi|91085015|ref|XP_973533.1|  PREDICTED: similar to mitochon...   310   7e-83
gi|125778428|ref|XP_001359972.1|  GA20754-PA [Drosophila pse...   306   1e-81
gi|4587985|gb|AAD25927.1|AF084828_1  major allergenic protei...   306   1e-81
gi|24647881|ref|NP_650696.1|  CG7998 CG7998-PA [Drosophila m...   305   2e-81
gi|66513092|ref|XP_392478.2|  PREDICTED: similar to mitochon...   305   4e-81
gi|47224065|emb|CAG12894.1|  unnamed protein product [Tetrao...   304   6e-81
gi|67043759|gb|AAY63978.1|  mitochondrial malate dehydrogena...   304   7e-81
gi|154336107|ref|XP_001564289.1|  malate dehydrogenase, puta...   301   3e-80
gi|17554310|ref|NP_498457.1|  Malate DeHydrogenase family me...   301   3e-80
gi|85090420|ref|XP_958408.1|  malate dehydrogenase, mitochon...   300   1e-79
gi|157776870|ref|XP_001666501.1|  hypothetical protein CBG15...   300   1e-79
gi|14583133|gb|AAK69767.1|AF390561_1  malate dehydrogenase [...   299   2e-79
gi|115489718|ref|NP_001067346.1|  Os12g0632700 [Oryza sativa...   298   2e-79
gi|2827080|gb|AAB99755.1|  malate dehydrogenase precursor [M...   298   3e-79
gi|115651961|ref|XP_792004.2|  PREDICTED: similar to malate ...   298   5e-79
gi|148237590|ref|NP_001085326.1|  MGC79037 protein [Xenopus ...   297   6e-79
gi|56758570|gb|AAW27425.1|  SJCHGC06124 protein [Schistosoma...   297   8e-79
gi|71003768|ref|XP_756550.1|  hypothetical protein UM00403.1...   296   9e-79
gi|39960255|ref|XP_364559.1|  hypothetical protein MGG_09367...   296   1e-78
gi|47531133|gb|AAT35230.1|  mitochondrial malate dehydrogena...   295   2e-78
gi|10444078|gb|AAG17699.1|AF280052_1  mitochondrial malate d...   295   4e-78
gi|58332672|ref|NP_001011412.1|  mitochondrial malate dehydr...   295   4e-78
gi|147774268|emb|CAN65552.1|  hypothetical protein [Vitis vi...   295   4e-78
gi|146098513|ref|XP_001468403.1|  malate dehydrogenase [Leis...   295   4e-78
gi|147899037|ref|NP_001086452.1|  mitochondrial malate dehyd...   294   4e-78
gi|2827084|gb|AAB99757.1|  malate dehydrogenase precursor [M...   294   7e-78
gi|157875427|ref|XP_001686105.1|  malate dehydrogenase, puta...   293   8e-78
gi|115438875|ref|NP_001043717.1|  Os01g0649100 [Oryza sativa...   293   9e-78
gi|24638017|sp|P83373|MDHM_FRAAN  Malate dehydrogenase, mito...   293   1e-77
gi|149247042|ref|XP_001527946.1|  malate dehydrogenase, mito...   293   1e-77
gi|121711589|ref|XP_001273410.1|  malate dehydrogenase, NAD-...   292   2e-77
gi|147866868|emb|CAN83064.1|  hypothetical protein [Vitis vi...   292   2e-77
gi|115473517|ref|NP_001060357.1|  Os07g0630800 [Oryza sativa...   291   3e-77
gi|1170897|sp|P46488|MDHG_CUCSA  Malate dehydrogenase, glyox...   291   3e-77
gi|169766066|ref|XP_001817504.1|  [Aspergillus oryzae] >gi|8...   291   3e-77
gi|6746611|gb|AAF27650.1|AF218064_1  malate dehydrogenase pr...   291   4e-77
gi|37725953|gb|AAO27260.1|  putative malate dehydrogenase [P...   291   5e-77
gi|7798706|gb|AAF69802.1|AF195869_1  malate dehydrogenase [V...   291   5e-77
gi|3377762|gb|AAC28106.1|  nodule-enhanced malate dehydrogen...   291   6e-77
gi|15227752|ref|NP_179863.1|  PMDH1 (PEROXISOMAL NAD-MALATE ...   290   7e-77
gi|19075316|ref|NP_587816.1|  malate dehydrogenase [Schizosa...   290   8e-77
gi|15232468|ref|NP_188120.1|  malate dehydrogenase (NAD), mi...   290   1e-76
gi|109066259|ref|XP_001114888.1|  PREDICTED: similar to mito...   290   1e-76
gi|47085883|ref|NP_998296.1|  hypothetical protein LOC406405...   289   2e-76
gi|60593475|pdb|1SEV|A  Chain A, Mature And Translocatable F...   289   2e-76
gi|126894|sp|P19446|MDHG_CITLA  Malate dehydrogenase, glyoxy...   289   2e-76
gi|70984070|ref|XP_747556.1|  malate dehydrogenase, NAD-depe...   288   4e-76
gi|169977|gb|AAC37464.1|  malate dehydrogenase                    287   5e-76
gi|1346501|sp|P37228|MDHG_SOYBN  Malate dehydrogenase, glyox...   287   5e-76
gi|126314424|ref|XP_001366592.1|  PREDICTED: similar to Mala...   287   5e-76
gi|115465579|ref|NP_001056389.1|  Os05g0574400 [Oryza sativa...   287   5e-76
gi|169776887|ref|XP_001822909.1|  [Aspergillus oryzae] >gi|8...   287   6e-76
gi|121703522|ref|XP_001270025.1|  malate dehydrogenase, NAD-...   287   6e-76
gi|115399894|ref|XP_001215536.1|  malate dehydrogenase, mito...   287   6e-76
gi|60593487|pdb|1SMK|A  Chain A, Mature And Translocatable F...   286   9e-76
gi|75040807|sp|Q5NVR2|MDHM_PONPY  Malate dehydrogenase, mito...   286   1e-75
gi|18404382|ref|NP_564625.1|  malate dehydrogenase (NAD), mi...   286   1e-75
gi|115476564|ref|NP_001061878.1|  Os08g0434300 [Oryza sativa...   286   1e-75
gi|21592905|gb|AAM64855.1|  mitochondrial NAD-dependent mala...   286   1e-75
gi|125528248|gb|EAY76362.1|  hypothetical protein OsI_004209...   286   2e-75
gi|115440823|ref|NP_001044691.1|  Os01g0829800 [Oryza sativa...   286   2e-75
gi|5929964|gb|AAD56659.1|  malate dehydrogenase [Glycine max]     286   2e-75
gi|2827078|gb|AAB99754.1|  malate dehydrogenase precursor [M...   286   2e-75
gi|33439518|gb|AAQ18808.1|  mitochondrial malate dehydrogena...   285   2e-75
gi|3273828|gb|AAC24855.1|  nodule-enhanced malate dehydrogen...   285   2e-75
gi|145250065|ref|XP_001396546.1|  hypothetical protein An15g...   285   2e-75
gi|119467850|ref|XP_001257731.1|  malate dehydrogenase, NAD-...   285   3e-75
gi|126896|sp|P17783|MDHM_CITLA  Malate dehydrogenase, mitoch...   285   3e-75
gi|49168580|emb|CAG38785.1|  MDH2 [Homo sapiens]                  285   3e-75
gi|52139820|gb|AAU29200.1|  glyoxisomal malate dehydrogenase...   285   3e-75
gi|5123836|emb|CAB45387.1|  NAD-malate dehydrogenase [Nicoti...   285   3e-75
gi|21735621|ref|NP_005909.2|  mitochondrial malate dehydroge...   285   3e-75
gi|125561648|gb|EAZ07096.1|  hypothetical protein OsI_028328...   285   3e-75
gi|6648067|sp|P40926|MDHM_HUMAN  Malate dehydrogenase, mitoc...   285   3e-75
gi|114614114|ref|XP_001156205.1|  PREDICTED: mitochondrial m...   285   3e-75
gi|119482986|ref|XP_001261521.1|  malate dehydrogenase, NAD-...   285   3e-75
gi|47119068|gb|AAP37966.2|  malate dehydrogenase [Paracoccid...   285   3e-75
gi|42407501|dbj|BAD10618.1|  putative NAD-malate dehydrogena...   285   4e-75
gi|93279232|pdb|2DFD|A  Chain A, Crystal Structure Of Human ...   284   5e-75
gi|42476181|ref|NP_112413.2|  malate dehydrogenase, mitochon...   284   5e-75
gi|387422|gb|AAA39509.1|  malate dehydrogenase                    284   5e-75
gi|89574107|gb|ABD77279.1|  mitochondrial malate dehydrogena...   284   5e-75
gi|50758110|ref|XP_415765.1|  PREDICTED: similar to Malate d...   284   5e-75
gi|70986899|ref|XP_748936.1|  malate dehydrogenase, NAD-depe...   284   5e-75
gi|73957776|ref|XP_849944.1|  PREDICTED: similar to malate d...   284   6e-75
gi|89574105|gb|ABD77278.1|  mitochondrial malate dehydrogena...   284   6e-75
>gi|71746908|ref|XP_822509.1| mitochondrial malate dehydrogenase [Trypanosoma brucei TREU927]
 gi|70832177|gb|EAN77681.1| mitochondrial malate dehydrogenase [Trypanosoma brucei]
          Length = 318

 Score =  585 bits (1508), Expect = e-165,   Method: Composition-based stats.
 Identities = 307/318 (96%), Positives = 307/318 (96%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK
Sbjct: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60

Query: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120
           VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI
Sbjct: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120

Query: 121 GXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180
           G           IASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV
Sbjct: 121 GVVSNPVNSVVPIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180

Query: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM
Sbjct: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240

Query: 241 SSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHKPVFDAYEQSLLEKC 300
           SSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHKPVFDAYEQSLLEKC
Sbjct: 241 SSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHKPVFDAYEQSLLEKC 300

Query: 301 VADLEKNIAAGFAFGSRQ 318
           VADLEKNIAAGFAFGSRQ
Sbjct: 301 VADLEKNIAAGFAFGSRQ 318
>gi|2605782|gb|AAC27101.1| malate dehydrogenase [Trypanosoma brucei]
          Length = 318

 Score =  583 bits (1503), Expect = e-165,   Method: Composition-based stats.
 Identities = 306/318 (96%), Positives = 306/318 (96%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK
Sbjct: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60

Query: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120
           VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI
Sbjct: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120

Query: 121 GXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180
           G           IASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV
Sbjct: 121 GVVSNPVNSVVPIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180

Query: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           GGHSGPTIIPLLSQAGVSLTEEQVKAIT RVQYGGDEVVKAKGGAGSATLSMAYAAGEWM
Sbjct: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITHRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240

Query: 241 SSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHKPVFDAYEQSLLEKC 300
           SSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHKPVFDAYEQSLLEKC
Sbjct: 241 SSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHKPVFDAYEQSLLEKC 300

Query: 301 VADLEKNIAAGFAFGSRQ 318
           VADLEKNIAAGFAFGSRQ
Sbjct: 301 VADLEKNIAAGFAFGSRQ 318
>gi|71664243|ref|XP_819104.1| malate dehydrogenase, putative [Trypanosoma cruzi strain CL Brener]
 gi|70884391|gb|EAN97253.1| malate dehydrogenase, putative [Trypanosoma cruzi]
          Length = 318

 Score =  437 bits (1124), Expect = e-121,   Method: Composition-based stats.
 Identities = 220/314 (70%), Positives = 258/314 (82%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           M  SA    KVAVLGAAGGIGQPLSL+LK NPLVS LSCYD+ G  GVAADLSHICSPAK
Sbjct: 2   MHNSAACLSKVAVLGAAGGIGQPLSLLLKNNPLVSALSCYDLRGAPGVAADLSHICSPAK 61

Query: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120
           VTG+ K+E++KA+DGA++V+IPAG PRKPGMTR+DLF+ NA+IVRDLV ACAK CPKA I
Sbjct: 62  VTGYTKEEINKALDGAELVLIPAGVPRKPGMTRDDLFNTNASIVRDLVIACAKVCPKAFI 121

Query: 121 GXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180
           G           IA+E LKKAGVFDPARLFG+TTLD+VRARTFVAEA GKSPYDV+V VV
Sbjct: 122 GVVSNPVNSTVPIAAETLKKAGVFDPARLFGVTTLDLVRARTFVAEAGGKSPYDVHVPVV 181

Query: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           GGHSGPTI+PLLSQ+GV L++ QVKAIT RVQYGGDEVV+AK GAGSATLSMAYA  EW 
Sbjct: 182 GGHSGPTIVPLLSQSGVELSDSQVKAITHRVQYGGDEVVQAKDGAGSATLSMAYAGAEWS 241

Query: 241 SSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHKPVFDAYEQSLLEKC 300
           +S+LK LRGD G+VE T++QTD+ P + +F C VE+GK GV K HKP  + +E+SL+EK 
Sbjct: 242 NSILKALRGDSGVVEYTFIQTDVWPNLPYFSCAVEIGKNGVVKAHKPQLNKFEESLMEKA 301

Query: 301 VADLEKNIAAGFAF 314
           + DL+KNIA G +F
Sbjct: 302 IVDLQKNIARGKSF 315
>gi|71414199|ref|XP_809210.1| mitochondrial malate dehydrogenase, putative [Trypanosoma cruzi
           strain CL Brener]
 gi|70873557|gb|EAN87359.1| mitochondrial malate dehydrogenase, putative [Trypanosoma cruzi]
          Length = 301

 Score =  415 bits (1066), Expect = e-114,   Method: Composition-based stats.
 Identities = 209/299 (69%), Positives = 245/299 (81%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           M  SA    KVAVLGAAGGIGQPLSL+LK NPLVS LSCYD+ G  GVAADLSHICSPAK
Sbjct: 2   MHNSAACLSKVAVLGAAGGIGQPLSLLLKNNPLVSALSCYDLRGAPGVAADLSHICSPAK 61

Query: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120
           VTG+ K+E++KA+DGA++V+IPAG PRKPGMTR+DLF+ NA+IVRDLV  CAK CPKA I
Sbjct: 62  VTGYTKEEINKALDGAELVLIPAGVPRKPGMTRDDLFNTNASIVRDLVITCAKVCPKAFI 121

Query: 121 GXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180
           G           IA+E LKKAGVFDPARLFG+TTLD+VRARTFVAEA GKSPYDV+V VV
Sbjct: 122 GVVSNPVNSTVPIAAETLKKAGVFDPARLFGVTTLDLVRARTFVAEAGGKSPYDVHVPVV 181

Query: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           GGHSGPTI+PLLSQ+G+ L++ QVKAIT RVQYGGDEVV+AK GAGSATLSMAYA  EW 
Sbjct: 182 GGHSGPTIVPLLSQSGLELSDSQVKAITHRVQYGGDEVVQAKDGAGSATLSMAYAGAEWS 241

Query: 241 SSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHKPVFDAYEQSLLEK 299
           +S+LK LRGD G+VE T++QTD+ P + +F C VE+GK GV K HK   + +E+SL+EK
Sbjct: 242 NSILKALRGDSGVVEYTFIQTDVWPNLPYFSCAVEIGKNGVVKAHKTQLNKFEESLMEK 300
>gi|157875425|ref|XP_001686104.1| malate dehydrogenase [Leishmania major]
 gi|68129178|emb|CAJ07715.1| malate dehydrogenase [Leishmania major]
          Length = 317

 Score =  379 bits (973), Expect = e-103,   Method: Composition-based stats.
 Identities = 197/318 (61%), Positives = 239/318 (75%), Gaps = 2/318 (0%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           MR S    F+VAVLGAAGGIGQPLSL+LK N  V  L  YD+ G  GVAADLSHIC+PAK
Sbjct: 1   MRRSQGCFFRVAVLGAAGGIGQPLSLLLKNNKYVKELKLYDVKGGPGVAADLSHICAPAK 60

Query: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120
           VTG+ KDEL +AV+ ADVV+IPAG PRKPGMTR+DLF+ NA+IVRDL  A     PKA++
Sbjct: 61  VTGYTKDELSRAVENADVVVIPAGIPRKPGMTRDDLFNTNASIVRDLAIAVGTHAPKAIV 120

Query: 121 GXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180
           G           +A+E LKK GV+DPARLFG+TTLDVVRARTFVAEA G SPYDV+V V+
Sbjct: 121 GIITNPVNSTVPVAAEALKKVGVYDPARLFGVTTLDVVRARTFVAEALGASPYDVDVPVI 180

Query: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           GGHSG TI+PLLS    SL+EEQV+ +T R+Q+GGDEVVKAK GAGSATLSMA+A  EW 
Sbjct: 181 GGHSGETIVPLLS-GFPSLSEEQVRQLTHRIQFGGDEVVKAKDGAGSATLSMAFAGNEWT 239

Query: 241 SSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHK-PVFDAYEQSLLEK 299
           ++VL+ L G+KG+V CTYVQ+ + P   FF  PV LG  GVEKI+  P+ +AYE+ L+ K
Sbjct: 240 TAVLRALSGEKGVVVCTYVQSTVEPSCAFFSSPVLLGNSGVEKIYPVPMLNAYEEKLMAK 299

Query: 300 CVADLEKNIAAGFAFGSR 317
           C+  L+ NI  G AF ++
Sbjct: 300 CLEGLQSNITKGIAFSNK 317
>gi|146098508|ref|XP_001468402.1| malate dehydrogenase [Leishmania infantum]
 gi|134072770|emb|CAM71486.1| malate dehydrogenase [Leishmania infantum]
          Length = 317

 Score =  375 bits (964), Expect = e-102,   Method: Composition-based stats.
 Identities = 194/318 (61%), Positives = 238/318 (74%), Gaps = 2/318 (0%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           MR S    F+VAVLGAAGGIGQPLSL+LK N  V  L  YD+ G  GVAADLSHIC+PAK
Sbjct: 1   MRRSQACFFRVAVLGAAGGIGQPLSLLLKNNKYVKELKLYDVKGAPGVAADLSHICAPAK 60

Query: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120
           VTG+ KDEL +AV+G DVV+IPAG PRKPGMTR+DLF+ NA+IVRDL  A     PKA++
Sbjct: 61  VTGYTKDELSRAVEGVDVVVIPAGIPRKPGMTRDDLFNTNASIVRDLAIAVGTHAPKAIV 120

Query: 121 GXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180
           G           +A+E LKK GV+DPARLFG+TTLDVVRARTFV EA GKSP + ++ VV
Sbjct: 121 GIITNPVNSTVPVAAEALKKVGVYDPARLFGVTTLDVVRARTFVGEALGKSPLEFDIPVV 180

Query: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           GGHSG TI+PLLS    SL+EEQV+ +T R+Q+GGDEVVKAK GAGSATLSMA+A  EW 
Sbjct: 181 GGHSGETIVPLLS-GFPSLSEEQVRQLTHRIQFGGDEVVKAKDGAGSATLSMAFAGNEWT 239

Query: 241 SSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHK-PVFDAYEQSLLEK 299
           ++VL+ L G+KG+V CTYVQ+ + P   FF  PV LG  GVEKI+  P+ ++YE+ L+ K
Sbjct: 240 TAVLRALSGEKGVVVCTYVQSTVEPSCAFFSSPVLLGNSGVEKIYPVPMLNSYEEKLMAK 299

Query: 300 CVADLEKNIAAGFAFGSR 317
           C+  L+ NI  G AFG++
Sbjct: 300 CLEGLQGNIKKGIAFGNK 317
>gi|154336109|ref|XP_001564290.1| malate dehydrogenase [Leishmania braziliensis MHOM/BR/75/M2904]
 gi|134061325|emb|CAM38349.1| malate dehydrogenase [Leishmania braziliensis]
 gi|155675702|gb|ABU25171.1| malate dehydrogenase [Leishmania peruviana]
 gi|163963015|gb|ABY50459.1| malate dehydrogenase [Leishmania braziliensis]
 gi|163963041|gb|ABY50472.1| malate dehydrogenase [Leishmania peruviana]
 gi|163963043|gb|ABY50473.1| malate dehydrogenase [Leishmania peruviana]
 gi|163963045|gb|ABY50474.1| malate dehydrogenase [Leishmania peruviana]
 gi|163963047|gb|ABY50475.1| malate dehydrogenase [Leishmania peruviana]
 gi|163963049|gb|ABY50476.1| malate dehydrogenase [Leishmania peruviana]
 gi|163963051|gb|ABY50477.1| malate dehydrogenase [Leishmania peruviana]
 gi|163963053|gb|ABY50478.1| malate dehydrogenase [Leishmania peruviana]
 gi|163963055|gb|ABY50479.1| malate dehydrogenase [Leishmania peruviana]
 gi|163963057|gb|ABY50480.1| malate dehydrogenase [Leishmania peruviana]
          Length = 317

 Score =  372 bits (954), Expect = e-101,   Method: Composition-based stats.
 Identities = 195/318 (61%), Positives = 238/318 (74%), Gaps = 2/318 (0%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           MR S     +VAVLGAAGGIGQPL+L+LK N  V  L  YDI G  GVAADLSHICS AK
Sbjct: 1   MRCSRAYFSRVAVLGAAGGIGQPLALLLKNNAHVKELKLYDIKGAPGVAADLSHICSSAK 60

Query: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120
           VTG+ ++EL+KAV   D+V+IPAG PRKPGMTR+DLF+ NA IVRDLV+A A+  PKA+I
Sbjct: 61  VTGYSQEELNKAVQNTDLVLIPAGVPRKPGMTRDDLFNTNAGIVRDLVTAVARAAPKAII 120

Query: 121 GXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180
           G           +A+E LKK G +DP RLFG+TTLDVVRARTFVAEA G+SPYD++V VV
Sbjct: 121 GVISNPVNSTVPVAAETLKKLGAYDPGRLFGVTTLDVVRARTFVAEALGRSPYDIDVPVV 180

Query: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           GGHSG TI+PLLS    SL++EQV+ +T R+Q+GGDEVVKAK GAGSATLSMA+A  EW 
Sbjct: 181 GGHSGETIVPLLS-GFPSLSKEQVEQLTYRIQFGGDEVVKAKSGAGSATLSMAHAGNEWA 239

Query: 241 SSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIH-KPVFDAYEQSLLEK 299
           ++VL+ L G+KG+  CTYV++ + P   FF  PVELGK GVEKIH  P  +AYE+ L+ K
Sbjct: 240 TAVLRALSGEKGVTVCTYVESSVEPSCTFFSSPVELGKNGVEKIHCVPKLNAYEEKLMAK 299

Query: 300 CVADLEKNIAAGFAFGSR 317
           C+  L+ NI  G AFG +
Sbjct: 300 CLEGLQGNIKKGVAFGCK 317
>gi|154336105|ref|XP_001564288.1| malate dehydrogenase, putative [Leishmania braziliensis
           MHOM/BR/75/M2904]
 gi|134061323|emb|CAM38347.1| malate dehydrogenase, putative [Leishmania braziliensis]
          Length = 325

 Score =  367 bits (941), Expect = e-100,   Method: Composition-based stats.
 Identities = 198/319 (62%), Positives = 239/319 (74%), Gaps = 3/319 (0%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           MR+S TL  +VAVLGAAGGIGQPLSL+LK +PLV+ LS YDI G TGVAADL HI SPA+
Sbjct: 1   MRSSVTLLSRVAVLGAAGGIGQPLSLLLKCSPLVTDLSLYDIRGGTGVAADLFHIPSPAE 60

Query: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120
           VTG   DEL KAV GAD+V++ AG PRKPGMTR+DLF+ NA IVRDLV+A A+  PKA+I
Sbjct: 61  VTGFASDELEKAVKGADLVLVAAGIPRKPGMTRDDLFNTNAGIVRDLVTAVARAAPKAII 120

Query: 121 GXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180
           G           +A+E LKK G +DP RLFG+TTLDVVRARTFVAEA G+SPYD++V VV
Sbjct: 121 GVISNPVNSTVPVAAETLKKLGAYDPGRLFGVTTLDVVRARTFVAEALGRSPYDIDVPVV 180

Query: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           GGHSG TI+PLLS    SL++EQV+ +T R+Q+GGDEVVKAK G GSATLSMAYAA +W 
Sbjct: 181 GGHSGETIVPLLS-GFPSLSKEQVEQLTYRIQFGGDEVVKAKAGKGSATLSMAYAASDWS 239

Query: 241 SSVLKGLRGDKGIVECTYVQTDI-IPGVNFFGCPVELGKGGVEKIHK-PVFDAYEQSLLE 298
           +S+LK LRGDKGI E  +V+ D+  P  +FFGC VELG  GVE++   P  +AYEQ LL+
Sbjct: 240 TSILKALRGDKGIAEYAFVENDLQQPHCHFFGCAVELGTHGVERVLPIPALNAYEQQLLD 299

Query: 299 KCVADLEKNIAAGFAFGSR 317
            CV  L   +  G  F  +
Sbjct: 300 ACVPALSAELRKGVDFAVK 318
>gi|146098517|ref|XP_001468404.1| malate dehydrogenase [Leishmania infantum]
 gi|134072772|emb|CAM71488.1| malate dehydrogenase, putative [Leishmania infantum]
          Length = 325

 Score =  358 bits (918), Expect = 4e-97,   Method: Composition-based stats.
 Identities = 196/319 (61%), Positives = 232/319 (72%), Gaps = 3/319 (0%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           MR+SA   F+VAVLGAAGGIGQPLSL+LK +PLV+ LS YDI G  GVAADLSHI SPA+
Sbjct: 1   MRSSAARLFRVAVLGAAGGIGQPLSLLLKCSPLVTSLSLYDIRGGPGVAADLSHIPSPAE 60

Query: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120
           VTG    EL KAV GAD+ ++ AG PRKPGMTR+DLF  NA+IVRDL  A     PKA++
Sbjct: 61  VTGFSSGELEKAVKGADLALVVAGIPRKPGMTRDDLFHTNASIVRDLAIAVGTHAPKAIV 120

Query: 121 GXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180
           G           +A+E LKK GV+DPARLFG+TTLDVVRARTFV EA G SPYDV+V VV
Sbjct: 121 GIITNPVNSTVPVAAEALKKVGVYDPARLFGVTTLDVVRARTFVGEALGASPYDVDVPVV 180

Query: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           GGHSG TI+PLLS    SL+EEQV+ +T R+Q+GGDEVVKAK GAGSATLSMAYAA EW 
Sbjct: 181 GGHSGETIVPLLS-GFPSLSEEQVRQLTHRIQFGGDEVVKAKNGAGSATLSMAYAASEWS 239

Query: 241 SSVLKGLRGDKGIVECTYVQTDII-PGVNFFGCPVELGKGGVEKI-HKPVFDAYEQSLLE 298
            S+LK LRGD+GI+E   V++D+  P   FFGC VELG  GVE++   P  +AYEQ LL+
Sbjct: 240 ISMLKALRGDRGIIEYALVESDMQRPHSRFFGCAVELGTNGVERVLPMPKLNAYEQQLLD 299

Query: 299 KCVADLEKNIAAGFAFGSR 317
            C+  L      G  F  +
Sbjct: 300 ACLPALSAEFRKGVDFAVK 318
>gi|157875429|ref|XP_001686106.1| malate dehydrogenase, putative [Leishmania major]
 gi|68129180|emb|CAJ07717.1| malate dehydrogenase, putative [Leishmania major]
          Length = 325

 Score =  357 bits (915), Expect = 7e-97,   Method: Composition-based stats.
 Identities = 197/313 (62%), Positives = 231/313 (73%), Gaps = 3/313 (0%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           MR+SAT  F+VAVLGAAGGIGQPLSL+LK +PLV+ LS YDI G  GVAADLSHI SPA+
Sbjct: 1   MRSSATRLFRVAVLGAAGGIGQPLSLLLKCSPLVTSLSLYDIRGGPGVAADLSHIPSPAE 60

Query: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120
           V G    EL KAV GAD+V++ AG PRKPGMTR+DL   NA+IVRDL  A     PKA++
Sbjct: 61  VIGFSSGELEKAVKGADLVLVVAGIPRKPGMTRDDLLHTNASIVRDLAIAVGTHAPKAIV 120

Query: 121 GXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180
           G           +A+E LKK GV+DPARLFG+TTLDVVRARTFVAEA G SPYDV+V V+
Sbjct: 121 GIITNPVNSTVPVAAEALKKVGVYDPARLFGVTTLDVVRARTFVAEALGASPYDVDVPVI 180

Query: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           GGHSG TI+PLLS    SL+EEQV+ +T R+Q+GGDEVVKAK GAGSATLSMAYAA EW 
Sbjct: 181 GGHSGETIVPLLS-GFPSLSEEQVRQLTHRIQFGGDEVVKAKDGAGSATLSMAYAASEWS 239

Query: 241 SSVLKGLRGDKGIVECTYVQTDI-IPGVNFFGCPVELGKGGVEKI-HKPVFDAYEQSLLE 298
            S+LK LRGD+GIVE   V++D+  P   FFGC VELG  GVE++   P  +AYEQ LL+
Sbjct: 240 ISMLKALRGDRGIVEYALVESDMQQPHSRFFGCAVELGTHGVERVLPMPKLNAYEQQLLD 299

Query: 299 KCVADLEKNIAAG 311
            CV  L      G
Sbjct: 300 ACVPALSAEFRKG 312
>gi|58269764|ref|XP_572038.1| malate dehydrogenase [Cryptococcus neoformans var. neoformans
           JEC21]
 gi|134113795|ref|XP_774482.1| hypothetical protein CNBG1280 [Cryptococcus neoformans var.
           neoformans B-3501A]
 gi|50257120|gb|EAL19835.1| hypothetical protein CNBG1280 [Cryptococcus neoformans var.
           neoformans B-3501A]
 gi|57228274|gb|AAW44731.1| malate dehydrogenase, putative [Cryptococcus neoformans var.
           neoformans JEC21]
          Length = 338

 Score =  317 bits (813), Expect = 5e-85,   Method: Composition-based stats.
 Identities = 179/318 (56%), Positives = 221/318 (69%), Gaps = 7/318 (2%)

Query: 3   TSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAKVT 62
           +SA    KVAVLGAAGGIGQP+SL+LK NP V+ LS YDI G  GVAAD+SH+ + + V 
Sbjct: 19  SSARSNRKVAVLGAAGGIGQPMSLLLKQNPGVTGLSLYDIRGAPGVAADISHVNTHSTVK 78

Query: 63  GHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALIGX 122
           G  KD++ +A+ GA++VIIPAG PRKPGMTR+DLF+ NA+IVRDL  ACA+ CPKA IG 
Sbjct: 79  GFEKDDIKEALTGAEIVIIPAGVPRKPGMTRDDLFNTNASIVRDLAEACAEYCPKAFIGI 138

Query: 123 XXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVVGG 182
                     I +EVLKK GVFD  R+FGITTLDVVRA  F+ E  GK P D+ V VVGG
Sbjct: 139 ISNPVNSTVPIFAEVLKKKGVFDEKRVFGITTLDVVRASRFLGEIKGKDPKDIKVTVVGG 198

Query: 183 HSGPTIIPLLSQA--GVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           HSG TI+PLLSQ   G  ++ E  KA+  R+Q+GGDEVVKAK G GSATLSM YA   + 
Sbjct: 199 HSGVTIVPLLSQTPEGKDVSGEAYKALVNRIQFGGDEVVKAKAGTGSATLSMGYAGARFT 258

Query: 241 SSVLKGLRGDKGIVECTYVQTDII--PGVNFFGCPVELGKGGVEKIHKPV--FDAYEQSL 296
            S+++ L G+ GIVE T+V++ +    GV +F   VELG  GV+KI+ PV    A EQ L
Sbjct: 259 DSLIRALNGETGIVEPTFVKSPLYESEGVEYFASNVELGPEGVKKIN-PVGQLSAEEQEL 317

Query: 297 LEKCVADLEKNIAAGFAF 314
           L+ C+ DL KNI  G  F
Sbjct: 318 LKACLPDLVKNIKKGVDF 335
>gi|169865690|ref|XP_001839443.1| hypothetical protein CC1G_06656 [Coprinopsis cinerea okayama7#130]
 gi|116499451|gb|EAU82346.1| hypothetical protein CC1G_06656 [Coprinopsis cinerea okayama7#130]
          Length = 337

 Score =  314 bits (804), Expect = 6e-84,   Method: Composition-based stats.
 Identities = 175/318 (55%), Positives = 227/318 (71%), Gaps = 7/318 (2%)

Query: 3   TSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAKVT 62
           TSA  Q +VAVLGA GGIGQPLSL+LK++PLVS LS YDI G  GVAAD+SH+ + ++V 
Sbjct: 17  TSAVRQTRVAVLGAGGGIGQPLSLLLKSDPLVSSLSLYDIRGAPGVAADVSHVDTASEVK 76

Query: 63  GHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALIGX 122
           G+  D+L +A++GA VV+IPAG PRKPGMTR+DLF+ NA+IVRDL +A  +  P+A I  
Sbjct: 77  GYAADQLDQALEGAKVVVIPAGVPRKPGMTRDDLFNTNASIVRDLAAAIGRVSPEAHILI 136

Query: 123 XXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVVGG 182
                     I +  L+K G FDP R+FG+TTLDVVRA  FV E  GK+P D  + VVGG
Sbjct: 137 ISNPVNSTVPIVAATLEKQGKFDPRRVFGVTTLDVVRAARFVGEVTGKNPLDTPITVVGG 196

Query: 183 HSGPTIIPLLSQA--GVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           HSGPTI+PLLSQ+  G +++ E    +  R+QYGGDEVVKAK GAGSATLSMAYA  ++ 
Sbjct: 197 HSGPTIVPLLSQSPTGKTISGEAYGKVVHRIQYGGDEVVKAKDGAGSATLSMAYAGAKFT 256

Query: 241 SSVLKGLRGDKGIVECTYVQTDIIP--GVNFFGCPVELGKGGVEKIHKPV--FDAYEQSL 296
           +S+L+GL G+KG++  T+V++ +    G++FF   VELG  GV KIH P+    A EQ L
Sbjct: 257 NSLLRGLNGEKGVITPTFVKSPLYESQGIDFFSSNVELGTEGVAKIH-PIGEISAEEQKL 315

Query: 297 LEKCVADLEKNIAAGFAF 314
           LE C+ +L+KNI  G AF
Sbjct: 316 LEACLPELKKNIEKGKAF 333
>gi|157118108|ref|XP_001659012.1| malate dehydrogenase [Aedes aegypti]
 gi|108875864|gb|EAT40089.1| malate dehydrogenase [Aedes aegypti]
          Length = 419

 Score =  312 bits (799), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 172/316 (54%), Positives = 224/316 (70%), Gaps = 5/316 (1%)

Query: 3   TSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAKVT 62
           T++    KVAV GA+GGIGQPLSL+LK +PLV+ LS YDI    GVAADLSHI + +KVT
Sbjct: 101 TTSQNNVKVAVCGASGGIGQPLSLLLKQSPLVTELSLYDIVHTPGVAADLSHIETHSKVT 160

Query: 63  GHLKDE-LHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALIG 121
           G+   E L KA+  AD+VIIPAG PRKPGMTR+DLF+ NA+IVRDL + CAK CPKALIG
Sbjct: 161 GYNGAENLEKALANADIVIIPAGVPRKPGMTRDDLFNTNASIVRDLAAGCAKACPKALIG 220

Query: 122 XXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVVG 181
                      IA E L KAGV D  R+FG++TLD+VRA TF+ EAAG  P  VNV V+G
Sbjct: 221 IISNPVNSTVPIACETLAKAGVLDVKRVFGVSTLDIVRANTFIGEAAGVDPQKVNVPVIG 280

Query: 182 GHSGPTIIPLLSQA--GVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEW 239
           GHSG TIIP+LSQA   V+  ++++ A+T R+Q  G EVVKAK GAGSATLSMAYA   +
Sbjct: 281 GHSGVTIIPVLSQATPSVNFPQDKIAALTERIQEAGTEVVKAKAGAGSATLSMAYAGARF 340

Query: 240 MSSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEK-IHKPVFDAYEQSLLE 298
             ++ + ++G++ ++EC YV++D+     +F  P+ LGK G+EK +  P  +A+EQ LL+
Sbjct: 341 ALALARAMKGEQNVIECAYVRSDVTEA-KYFSTPLLLGKNGLEKNLGLPKLNAFEQELLK 399

Query: 299 KCVADLEKNIAAGFAF 314
           K + +L+KNI  G  F
Sbjct: 400 KALPELKKNIQKGEDF 415
>gi|4029338|emb|CAA76361.1| malate dehydrogenase [Piromyces sp. E2]
          Length = 316

 Score =  311 bits (798), Expect = 3e-83,   Method: Composition-based stats.
 Identities = 172/311 (55%), Positives = 218/311 (70%), Gaps = 7/311 (2%)

Query: 10  KVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAKVTGHLKDE- 68
           KVAVLGAAGGIGQPLSL+LK++P V+ L+ YDI    GVAADLSHIC+ AKVTG+   E 
Sbjct: 3   KVAVLGAAGGIGQPLSLLLKSHPQVTELNLYDIVNSPGVAADLSHICTKAKVTGYKGQEN 62

Query: 69  LHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALIGXXXXXXX 128
           L  A+ G D+V+IPAG PRKPGMTR+DLF++NA IV+ L    AK CPKA +        
Sbjct: 63  LDAALAGCDIVVIPAGIPRKPGMTRDDLFNINAGIVKGLAEGIAKNCPKAFVCIISNPVN 122

Query: 129 XXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVVGGHSGPTI 188
               I +EV KKAG +DP RLFG+T LD+VR+ TFV+E  G SP D  V V+GGHSG TI
Sbjct: 123 STVPICAEVFKKAGTYDPKRLFGVTLLDMVRSSTFVSECKGTSPADTKVTVIGGHSGVTI 182

Query: 189 IPLLSQA-GVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWMSSVLKGL 247
           +PLLSQ  G++ T+E+V+A+T R+Q+GGDEVVKAK GAGSATLSMAYAA  ++ S+++G 
Sbjct: 183 VPLLSQVKGLTFTQEEVEALTHRIQFGGDEVVKAKDGAGSATLSMAYAAARFVDSLIEGA 242

Query: 248 RGDKGIVECTYVQTDII--PGVNFFGCPVELGKGGVEKIHKPV--FDAYEQSLLEKCVAD 303
              K ++EC YV++ +    G +FF   +ELG  G EKI  P+     YEQ L + CV  
Sbjct: 243 FMKKPVIECAYVESPLAVDDGCSFFASAIELGPSGAEKI-LPIGPLSEYEQGLYKACVEQ 301

Query: 304 LEKNIAAGFAF 314
           L+ NIA G  F
Sbjct: 302 LKANIAKGVNF 312
>gi|91085015|ref|XP_973533.1| PREDICTED: similar to mitochondrial malate dehydrogenase precursor
           [Tribolium castaneum]
          Length = 336

 Score =  310 bits (795), Expect = 7e-83,   Method: Composition-based stats.
 Identities = 176/320 (55%), Positives = 226/320 (70%), Gaps = 5/320 (1%)

Query: 3   TSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAKVT 62
           TS     KVAV GA+GGIGQPLSL+LK +PLV+ LS YDI    GVAADLSHI +PAKV 
Sbjct: 18  TSKQNNVKVAVAGASGGIGQPLSLLLKQSPLVTELSLYDIVHTPGVAADLSHIETPAKVK 77

Query: 63  GHLKDE-LHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALIG 121
           G    E L KA +GA+V+IIPAG PRKPGMTR+DLF+ NA+IV+ L  A A+  PKALIG
Sbjct: 78  GFNGPENLKKAFEGAEVIIIPAGVPRKPGMTRDDLFNTNASIVQTLAEAAAESAPKALIG 137

Query: 122 XXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVVG 181
                      IA+EVLKKAG +DP RLFG++TLDVVRA TFVAE  G +P +V V V+G
Sbjct: 138 IISNPVNSTVPIAAEVLKKAGKYDPKRLFGVSTLDVVRANTFVAELKGLNPLEVKVPVIG 197

Query: 182 GHSGPTIIPLLSQAGVSLT--EEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEW 239
           GHSG TIIPL+SQA  S+T   +Q+KA+T R+Q  G EVVKAK GAGSATLSMAYA   +
Sbjct: 198 GHSGVTIIPLISQATPSVTFPPDQLKALTERIQEAGTEVVKAKAGAGSATLSMAYAGARF 257

Query: 240 MSSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEK-IHKPVFDAYEQSLLE 298
             S+++ L+G++ I+EC YV++++     +F  P+ LGK G+EK +       +EQ LL+
Sbjct: 258 AISLIRALKGEQNIIECAYVESNLTEA-KYFSTPLLLGKNGLEKNLGLGKLSDFEQDLLK 316

Query: 299 KCVADLEKNIAAGFAFGSRQ 318
           K + +L+KNI  G  F +++
Sbjct: 317 KAIPELKKNIQKGEDFVNKK 336
>gi|125778428|ref|XP_001359972.1| GA20754-PA [Drosophila pseudoobscura]
 gi|54639722|gb|EAL29124.1| GA20754-PA [Drosophila pseudoobscura]
          Length = 336

 Score =  306 bits (785), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 165/312 (52%), Positives = 217/312 (69%), Gaps = 5/312 (1%)

Query: 9   FKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAKVTGHL-KD 67
           FKV V GA+GGIGQPLSL+LK NPLV+ LS YDI    GVAADLSHI + +K  G +  D
Sbjct: 25  FKVTVCGASGGIGQPLSLLLKQNPLVTDLSLYDIVHTPGVAADLSHIDTKSKTVGFMGAD 84

Query: 68  ELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALIGXXXXXX 127
           +L +++ G+DVV+IPAG PRKPGMTR+DLF+VNA I++D+ S+ AK CPKALI       
Sbjct: 85  QLGESLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDIASSIAKNCPKALIAIITNPV 144

Query: 128 XXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVVGGHSGPT 187
                IA+E+LKKA V+DP RLFG++TLDVVRAR F+  A    P  V + V+GGHSG T
Sbjct: 145 NTCVPIAAEILKKASVYDPNRLFGVSTLDVVRARAFIGHALNVDPQTVQIPVIGGHSGVT 204

Query: 188 IIPLLSQAGVSL--TEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWMSSVLK 245
           I+P+LSQ+      +++ ++ +T R+Q  G EVVKAK GAGSATLSMAYA   +  S+LK
Sbjct: 205 ILPVLSQSQPLFKGSQDVIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARFAGSLLK 264

Query: 246 GLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGV-EKIHKPVFDAYEQSLLEKCVADL 304
           GL G+K ++EC+YVQ+ I     FF  P+ LGK G+ E +  P  + YE+ LLE  + +L
Sbjct: 265 GLNGEKNVIECSYVQSTITEA-TFFSTPLVLGKSGLKENLGLPKLNDYEKKLLEAAIPEL 323

Query: 305 EKNIAAGFAFGS 316
           +KNI  G  F +
Sbjct: 324 KKNIQKGIDFAN 335
>gi|4587985|gb|AAD25927.1|AF084828_1 major allergenic protein Mal f4 [Malassezia furfur]
          Length = 342

 Score =  306 bits (784), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 172/318 (54%), Positives = 214/318 (67%), Gaps = 6/318 (1%)

Query: 4   SATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAKVTG 63
           +A    KVAVLGA+GGIGQPLSL++K NP V+ L  YDI    GVAADLSHI +PA  +G
Sbjct: 23  TAAANRKVAVLGASGGIGQPLSLLMKLNPKVTELRLYDIRLAPGVAADLSHINTPAVTSG 82

Query: 64  HLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALIGXX 123
           + +D+L  AVDGA++V+IPAG PRKPGMTR+DLF+ NA+IVRDL    AK  PKA IG  
Sbjct: 83  YAQDDLEGAVDGAEIVLIPAGMPRKPGMTRDDLFNSNASIVRDLAKVVAKVAPKAYIGVI 142

Query: 124 XXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVVGGH 183
                    I +EV KKAGV+DP RLFG+TTLD  RA TF++  AG  P   NV V+GGH
Sbjct: 143 SNPVNSTVPIVAEVFKKAGVYDPKRLFGVTTLDTTRAATFLSGIAGSDPQTTNVPVIGGH 202

Query: 184 SGPTIIPLLSQAGVS---LTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           SG TI+PL+SQA         EQ   +  R+Q+GGDEVVKAK GAGSATLSMAYAA  + 
Sbjct: 203 SGVTIVPLISQAAQGDKVQAGEQYDKLVHRIQFGGDEVVKAKDGAGSATLSMAYAAAVFT 262

Query: 241 SSVLKGLRGDKGIVECTYVQTDIIPG-VNFFGCPVELGKGGVEKIHK-PVFDAYEQSLLE 298
             +LKGL G+  + +CT+V++ +    V+FF  PVE G  GV+ I   P   A EQ LL+
Sbjct: 263 EGLLKGLDGE-AVTQCTFVESPLFKDQVDFFASPVEFGPEGVKNIPALPKLTAEEQKLLD 321

Query: 299 KCVADLEKNIAAGFAFGS 316
            C+ DL KNI  G A+ +
Sbjct: 322 ACLPDLAKNIKKGVAWAA 339
>gi|24647881|ref|NP_650696.1| CG7998 CG7998-PA [Drosophila melanogaster]
 gi|7300357|gb|AAF55516.1| CG7998-PA [Drosophila melanogaster]
 gi|21430668|gb|AAM51012.1| RE60471p [Drosophila melanogaster]
 gi|116875723|gb|ABK30911.1| IP09655p [Drosophila melanogaster]
          Length = 336

 Score =  305 bits (782), Expect = 2e-81,   Method: Composition-based stats.
 Identities = 164/312 (52%), Positives = 217/312 (69%), Gaps = 5/312 (1%)

Query: 9   FKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAKVTGHL-KD 67
           +KV V GAAGGIGQPLSL+LK NPLV+ L+ YDI    GVAADLSHI + +K  G +  D
Sbjct: 25  YKVTVCGAAGGIGQPLSLLLKQNPLVTDLALYDIVHTPGVAADLSHIDTKSKTAGFIGAD 84

Query: 68  ELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALIGXXXXXX 127
           +L  ++ G+DVV+IPAG PRKPGMTR+DLF+VNA I++D+ ++ AK CPKAL+       
Sbjct: 85  QLGDSLKGSDVVVIPAGVPRKPGMTRDDLFNVNAGIIKDISNSIAKNCPKALVAIITNPV 144

Query: 128 XXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVVGGHSGPT 187
                IA+E+LKKAGV+DP RLFG++TLDVVRAR F+  A G  P  V + V+GGHSG T
Sbjct: 145 NTCVPIAAEILKKAGVYDPKRLFGVSTLDVVRARAFIGHALGVDPQTVQIPVIGGHSGVT 204

Query: 188 IIPLLSQAGVSL--TEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWMSSVLK 245
           I+P+LSQ+       ++ ++ +T R+Q  G EVVKAK GAGSATLSMAYA   +  S+LK
Sbjct: 205 ILPVLSQSQPLFKGNQDTIEKLTVRIQEAGTEVVKAKAGAGSATLSMAYAGARFAGSLLK 264

Query: 246 GLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGV-EKIHKPVFDAYEQSLLEKCVADL 304
           GL G+K ++EC+YVQ+ +     FF  P+ LGK GV E +  P  + YE+ LLE  + +L
Sbjct: 265 GLNGEKNVIECSYVQSTVTEA-TFFSTPLVLGKNGVQENLGLPKLNDYEKKLLEAAIPEL 323

Query: 305 EKNIAAGFAFGS 316
           +KNI  G  F +
Sbjct: 324 KKNIQKGIDFAN 335
>gi|66513092|ref|XP_392478.2| PREDICTED: similar to mitochondrial malate dehydrogenase precursor
           isoform 1 [Apis mellifera]
          Length = 338

 Score =  305 bits (780), Expect = 4e-81,   Method: Composition-based stats.
 Identities = 173/321 (53%), Positives = 222/321 (69%), Gaps = 6/321 (1%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           + TSA    KVA+LGA+GGIGQPLSL++K +PLV+ LS YD+    GVAADLSH+ +PAK
Sbjct: 20  LSTSAKCNAKVAILGASGGIGQPLSLLMKQSPLVTELSLYDVVNTPGVAADLSHMDTPAK 79

Query: 61  VTGHL-KDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKAL 119
           V  +   +EL  A+ G  VVIIPAG PRKPGMTR+DLFS NA+IVRDL  A A+  PKA 
Sbjct: 80  VKAYTGPEELKDALKGTQVVIIPAGVPRKPGMTRDDLFSTNASIVRDLTQAIAEASPKAF 139

Query: 120 IGXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQV 179
           I            IASEVLKKAGV+DP R+FG+TTLD+VRA TF+AEA G +P +V+V V
Sbjct: 140 IAIISNPVNSTVPIASEVLKKAGVYDPNRVFGVTTLDIVRANTFIAEAKGLNPQNVSVPV 199

Query: 180 VGGHSGPTIIPLLSQA--GVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAG 237
           +GGHSG TIIPL+SQ    VS  E++VKA+T R+Q  G EVVKAK G GSATLSMAYA  
Sbjct: 200 IGGHSGVTIIPLISQTKPSVSFPEDKVKALTMRIQEAGTEVVKAKAGTGSATLSMAYAGA 259

Query: 238 EWMSSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEK-IHKPVFDAYEQSL 296
            +  S++K L G++ I E  YV++D+     +F   V LGK G+EK +     +AYE+ L
Sbjct: 260 RFGFSLIKALNGER-ITEYCYVKSDVC-DTKYFSTAVVLGKAGIEKNLGIGNLNAYEKEL 317

Query: 297 LEKCVADLEKNIAAGFAFGSR 317
           L   + +L+KN+  G  F ++
Sbjct: 318 LNAAIPELKKNVEKGEKFMNK 338
>gi|47224065|emb|CAG12894.1| unnamed protein product [Tetraodon nigroviridis]
          Length = 337

 Score =  304 bits (778), Expect = 6e-81,   Method: Composition-based stats.
 Identities = 169/321 (52%), Positives = 219/321 (68%), Gaps = 5/321 (1%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           + TS     KVAVLGA+GGIGQPLSL+LK +PLVSHLS YDI    GVAADLSHI + A+
Sbjct: 16  LSTSTQNNAKVAVLGASGGIGQPLSLLLKNSPLVSHLSLYDIAHTPGVAADLSHIETKAQ 75

Query: 61  VTGHL-KDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKAL 119
           VTGH+  ++L  A+ G DVV+IPAG PRKPGMTR+DLF+ NATIV  L  ACA+ CP+A+
Sbjct: 76  VTGHMGPEQLGDALKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLADACARHCPEAM 135

Query: 120 IGXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQV 179
           +            I +EVLKK GV++P R+FG+TTLD+VRA TFVAE  G  P  VNV V
Sbjct: 136 LCIIANPVNSTIPITAEVLKKHGVYNPNRVFGVTTLDIVRANTFVAELKGLDPARVNVPV 195

Query: 180 VGGHSGPTIIPLLSQA--GVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAG 237
           +GGH+G TIIPL+SQ    V    EQ+ A+T R+Q  G EVVKAK GAGSATLSMAYA  
Sbjct: 196 IGGHAGKTIIPLISQCTPKVEFPAEQLSALTGRIQEAGTEVVKAKAGAGSATLSMAYAGA 255

Query: 238 EWMSSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEK-IHKPVFDAYEQSL 296
            +  SVL  + G +G+VEC +V+++      +F  P+ LGK G+EK +      A+E+ L
Sbjct: 256 RFTFSVLDAMNGKEGVVECAFVRSEETE-CKYFSTPLLLGKNGIEKNLGLGKLSAFEEKL 314

Query: 297 LEKCVADLEKNIAAGFAFGSR 317
           +  C+ +L+ +I  G  F ++
Sbjct: 315 VADCMDELKASIKKGEDFVAK 335
>gi|67043759|gb|AAY63978.1| mitochondrial malate dehydrogenase [Lysiphlebus testaceipes]
          Length = 340

 Score =  304 bits (778), Expect = 7e-81,   Method: Composition-based stats.
 Identities = 170/324 (52%), Positives = 222/324 (68%), Gaps = 9/324 (2%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           + TS     KVAV+GA+GGIGQPLSL+LK +PLV+ LS YDI    GVAADLSHI S +K
Sbjct: 20  LSTSTQRNAKVAVMGASGGIGQPLSLLLKQSPLVTELSLYDIVNTPGVAADLSHIDSNSK 79

Query: 61  VTGHL-KDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKAL 119
           VTG    ++L  ++ GA +VIIPAG PRKPGMTR+DLF+ NA+IVRDL    A+ CPKA 
Sbjct: 80  VTGFTGPEQLRDSLKGAQIVIIPAGVPRKPGMTRDDLFNTNASIVRDLAQGIAEVCPKAF 139

Query: 120 IGXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQV 179
           +            IASEVL+KAGV+DP R+FG+TTLD+VR+  F+ EA G  P  V V V
Sbjct: 140 VAIISNPVNSTVPIASEVLQKAGVYDPNRIFGVTTLDIVRSNAFIGEAKGLDPQKVAVPV 199

Query: 180 VGGHSGPTIIPLLSQAGVSLT--EEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAG 237
           +GGHSG TIIPL+SQA  S+T  ++++KA+T R+Q  G EVVKAK G GSATLSMAYA  
Sbjct: 200 IGGHSGITIIPLISQAKPSVTFPDDKLKALTERIQEAGTEVVKAKAGTGSATLSMAYAGA 259

Query: 238 EWMSSVLKGLRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEK---IHKPVFDAYEQ 294
            +  S+++ L G+  IVEC+YV+++ +    +F  PV  GK G+EK   I K     +EQ
Sbjct: 260 RFGFSLIRALNGEPNIVECSYVRSN-LNDAKYFSTPVFFGKNGIEKNFGIGK--LTPFEQ 316

Query: 295 SLLEKCVADLEKNIAAGFAFGSRQ 318
            LLE  + +L+KNI  G  F +++
Sbjct: 317 KLLEGAIPELKKNIQKGEDFVNKK 340
>gi|154336107|ref|XP_001564289.1| malate dehydrogenase, putative [Leishmania braziliensis
           MHOM/BR/75/M2904]
 gi|134061324|emb|CAM38348.1| malate dehydrogenase, putative [Leishmania braziliensis]
          Length = 331

 Score =  301 bits (772), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 152/316 (48%), Positives = 214/316 (67%), Gaps = 2/316 (0%)

Query: 1   MRTSATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAK 60
           M+ S   +FKVAVLGA+G IGQPLS+ L  N  VS L+ YDI    G+A DLSH     K
Sbjct: 1   MKQSILSRFKVAVLGASGAIGQPLSMALVQNKRVSDLALYDIVQPRGIAVDLSHFPRKVK 60

Query: 61  VTGHLKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALI 120
           + G+    +HKA+DGADVV++PAG PR+PGMT +DLF+ NA  V +L +A A+  PKA++
Sbjct: 61  IAGYPTKWIHKALDGADVVLMPAGMPRRPGMTHDDLFNTNALTVHELSAAVARYSPKAIL 120

Query: 121 GXXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVV 180
                       +A+E L++AGV+DP ++FG+ TL+++RAR  + + AG  P  ++V V+
Sbjct: 121 AIISNPLNSLVPVAAETLRRAGVYDPRKVFGLITLNMMRARKMLGDFAGLDPETLDVPVI 180

Query: 181 GGHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWM 240
           GGHSG TI+PL SQ+GV+LT EQ + +T RV+ GGDEVV+AK G GS++LSMA AA EW 
Sbjct: 181 GGHSGQTIVPLFSQSGVALTREQAEYLTHRVRVGGDEVVRAKEGHGSSSLSMALAAAEWT 240

Query: 241 SSVLKGLRGDKGIVECTYVQTDIIPG-VNFFGCPVELGKGGVEKIHK-PVFDAYEQSLLE 298
             VL+ + G+K ++ C++V++ +      FFG  VE+GK GVE++   P  D YE+  L+
Sbjct: 241 EGVLRAMDGEKNLLRCSFVESPLFADKCRFFGSTVEVGKEGVERVLPLPPLDEYEEEQLD 300

Query: 299 KCVADLEKNIAAGFAF 314
           +C+ DLEKNI  G  F
Sbjct: 301 RCLPDLEKNIRKGLLF 316
>gi|17554310|ref|NP_498457.1| Malate DeHydrogenase family member (mdh-1) [Caenorhabditis elegans]
 gi|3183074|sp|O02640|MDHM_CAEEL Probable malate dehydrogenase, mitochondrial precursor
 gi|2076896|gb|AAB53985.1| Malate dehydrogenase protein 1 [Caenorhabditis elegans]
          Length = 341

 Score =  301 bits (772), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 175/309 (56%), Positives = 216/309 (69%), Gaps = 5/309 (1%)

Query: 10  KVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAKVTGHL-KDE 68
           KVA+LGAAGGIGQPL L+LK +PLV+HL+ YD+    GVAADLSHI S AKVT H    E
Sbjct: 30  KVALLGAAGGIGQPLGLLLKQDPLVAHLALYDVVNTPGVAADLSHIDSNAKVTAHTGPKE 89

Query: 69  LHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALIGXXXXXXX 128
           L+ AV+ ADV++IPAG PRKPGMTR+DLF+ NA IVRDL +  AK  PKALI        
Sbjct: 90  LYAAVENADVIVIPAGVPRKPGMTRDDLFNTNAGIVRDLAAVIAKASPKALIAIITNPVN 149

Query: 129 XXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVVGGHSGPTI 188
               IASEVLKKAGV+DP R+FG+TTLDVVR++ FV+E  G       V VVGGH+G TI
Sbjct: 150 STVPIASEVLKKAGVYDPKRVFGVTTLDVVRSQAFVSELKGHDASKTVVPVVGGHAGITI 209

Query: 189 IPLLSQAGVS--LTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWMSSVLKG 246
           IPLLSQ   S   +EE++  +T R+Q  G EVV AK GAGSATLSMA A   + +++++G
Sbjct: 210 IPLLSQVKPSTKFSEEEISKLTPRIQDAGTEVVNAKAGAGSATLSMALAGARFANALVRG 269

Query: 247 LRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHK-PVFDAYEQSLLEKCVADLE 305
           ++G+K  V+C YV +D + GV +F  PVELG  GVEKI       AYEQ L++  V +L 
Sbjct: 270 IKGEKN-VQCAYVASDAVKGVEYFSTPVELGPNGVEKILGVGKVSAYEQKLIDASVPELN 328

Query: 306 KNIAAGFAF 314
           KNIA G AF
Sbjct: 329 KNIAKGVAF 337
>gi|85090420|ref|XP_958408.1| malate dehydrogenase, mitochondrial precursor [Neurospora crassa
           OR74A]
 gi|28919768|gb|EAA29172.1| malate dehydrogenase, mitochondrial precursor [Neurospora crassa
           OR74A]
          Length = 336

 Score =  300 bits (767), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 172/317 (54%), Positives = 214/317 (67%), Gaps = 8/317 (2%)

Query: 4   SATLQFKVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAKVTG 63
           SA    KV+VLGAAGGIGQPLSL+LK NP VS L+ YDI G  GV ADLSHI + + V G
Sbjct: 15  SARQLTKVSVLGAAGGIGQPLSLLLKLNPRVSELALYDIRGAPGVGADLSHINTKSTVKG 74

Query: 64  H--LKDELHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALIG 121
           +      L  A+ G+++V+IPAG PRKPGMTR+DLF+ NA+IVRDL  ACA+ CP+A I 
Sbjct: 75  YEPTASGLADALKGSEIVLIPAGVPRKPGMTRDDLFNTNASIVRDLAKACAESCPEANIL 134

Query: 122 XXXXXXXXXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVVG 181
                      I SE+ KKAGV++P RLFG+TTLDVVRA  FV+E  G  P D N+ VVG
Sbjct: 135 VISNPVNSTVPIVSEIFKKAGVYNPKRLFGVTTLDVVRASRFVSEIKGTDPKDENITVVG 194

Query: 182 GHSGPTIIPLLSQAGVSLTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWMS 241
           GHSG TI+PL SQ+      +  + I  RVQ+GGDEVVKAK GAGSATLSMA A      
Sbjct: 195 GHSGVTIVPLFSQSKHPELSKNEQLI-HRVQFGGDEVVKAKDGAGSATLSMAMAGARMAE 253

Query: 242 SVLKGLRGDKGIVECTYVQTDIIP--GVNFFGCPVELGKGGVEKIHKPV--FDAYEQSLL 297
           S+L+  +G+KG++E T+V + +    G++FF   VELG  GVEKI+ PV   D  EQ LL
Sbjct: 254 SLLRAAQGEKGVIEPTFVDSPLYKDQGIDFFASKVELGPNGVEKIY-PVGPVDEVEQKLL 312

Query: 298 EKCVADLEKNIAAGFAF 314
           + C+ DL+KNI  G  F
Sbjct: 313 DACLVDLKKNIQKGKDF 329
>gi|157776870|ref|XP_001666501.1| hypothetical protein CBG15213 [Caenorhabditis briggsae AF16]
 gi|39586104|emb|CAE69180.1| Hypothetical protein CBG15213 [Caenorhabditis briggsae]
          Length = 341

 Score =  300 bits (767), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 174/309 (56%), Positives = 216/309 (69%), Gaps = 5/309 (1%)

Query: 10  KVAVLGAAGGIGQPLSLILKTNPLVSHLSCYDIHGVTGVAADLSHICSPAKVTGHL-KDE 68
           KVA+LGAAGGIGQPL L+LK +PLV+HL+ YD+    GVAADLSHI S AKVT H    E
Sbjct: 30  KVALLGAAGGIGQPLGLLLKQDPLVAHLALYDVVNTPGVAADLSHIDSNAKVTAHTGPKE 89

Query: 69  LHKAVDGADVVIIPAGTPRKPGMTREDLFSVNATIVRDLVSACAKQCPKALIGXXXXXXX 128
           L+ AV+ ADV++IPAG PRKPGMTR+DLF+ NA IVRDL +  AK  PKALI        
Sbjct: 90  LYAAVENADVIVIPAGVPRKPGMTRDDLFNTNAGIVRDLAAVIAKASPKALIAIITNPVN 149

Query: 129 XXXXIASEVLKKAGVFDPARLFGITTLDVVRARTFVAEAAGKSPYDVNVQVVGGHSGPTI 188
               IASEVLKKAGV+DP R+FG+TTLDVVR++ FV+E  G       V VVGGH+G TI
Sbjct: 150 STVPIASEVLKKAGVYDPKRVFGVTTLDVVRSQAFVSELKGHDATKTVVPVVGGHAGITI 209

Query: 189 IPLLSQAGVS--LTEEQVKAITRRVQYGGDEVVKAKGGAGSATLSMAYAAGEWMSSVLKG 246
           IPLLSQ   S   +EE++  +T R+Q  G EVV AK GAGSATLSMA A   + +++++G
Sbjct: 210 IPLLSQVTPSTKFSEEEIAKLTPRIQDAGTEVVNAKAGAGSATLSMALAGARFANALVRG 269

Query: 247 LRGDKGIVECTYVQTDIIPGVNFFGCPVELGKGGVEKIHK-PVFDAYEQSLLEKCVADLE 305
           ++G+K  V+C YV +D + GV +F  PVELG  GVEKI       A+EQ L++  V +L 
Sbjct: 270 IKGEKN-VQCAYVASDAVKGVEYFSTPVELGPNGVEKILGVGKVSAFEQKLIDASVPELN 328

Query: 306 KNIAAGFAF 314
           KNIA G AF
Sbjct: 329 KNIAKGVAF 337