BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= XP_822615__[Trypanosoma_brucei]
(403 letters)
Database: nr.pal
6,348,806 sequences; 2,166,943,470 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71747120|ref|XP_822615.1| aspartate aminotransferase [Tr... 755 0.0
gi|71404025|ref|XP_804756.1| aspartate aminotransferase, pu... 481 e-134
gi|71411043|ref|XP_807788.1| aspartate aminotransferase, pu... 476 e-132
gi|14915799|gb|AAK73814.1|AF326988_1 aspartate aminotransfe... 429 e-118
gi|154344503|ref|XP_001568193.1| aspartate aminotransferase... 417 e-115
gi|84619611|emb|CAF06209.1| aspartate aminotransferase [Lei... 415 e-114
gi|84619665|emb|CAF06236.1| aspartate aminotransferase [Lei... 414 e-114
gi|46852001|gb|AAT02697.1| glutamate oxaloacetate [Leishman... 414 e-114
gi|33311168|gb|AAQ03600.1|AF416601_1 broad specificity amin... 414 e-114
gi|46852005|gb|AAT02699.1| glutamate oxaloacetate [Leishman... 413 e-113
gi|109450666|emb|CAJ40955.1| aspartate aminotransferase [Le... 413 e-113
gi|72547196|ref|XP_843191.1| aspartate aminotransferase, pu... 412 e-113
gi|146100586|ref|XP_001468898.1| aspartate aminotransferase... 411 e-113
gi|46852017|gb|AAT02705.1| glutamate oxaloacetate [Leishman... 411 e-113
gi|84619669|emb|CAF06238.1| aspartate aminotransferase [Lei... 410 e-113
gi|46852009|gb|AAT02701.1| glutamate oxaloacetate [Leishman... 410 e-112
gi|84619667|emb|CAF06237.1| aspartate aminotransferase [Lei... 410 e-112
gi|46852021|gb|AAT02707.1| glutamate oxaloacetate [Leishman... 406 e-111
gi|84619615|emb|CAF06211.1| aspartate aminotransferase [Lei... 405 e-111
gi|109450668|emb|CAJ40956.1| aspartate aminotransferase [Le... 405 e-111
gi|109450660|emb|CAJ40952.1| aspartate aminotransferase [Le... 400 e-109
gi|156364446|ref|XP_001626359.1| predicted protein [Nematos... 345 3e-93
gi|68302096|gb|AAY89413.1| aspartate aminotransferase [Onch... 337 7e-91
gi|170085195|ref|XP_001873821.1| glutamic oxaloacetic trans... 334 7e-90
gi|66811806|ref|XP_640082.1| aspartate aminotransferase [Di... 331 6e-89
gi|170585668|ref|XP_001897604.1| aspartate aminotransferase... 331 8e-89
gi|33307009|gb|AAQ02891.1|AF395205_1 aspartate aminotransfe... 328 3e-88
gi|157132966|ref|XP_001662725.1| aspartate aminotransferase... 326 2e-87
gi|809192|pdb|2CST|A Chain A, Crystal Structure Of The Clos... 323 2e-86
gi|71981858|ref|NP_491413.2| C44E4.3 [Caenorhabditis elegan... 322 2e-86
gi|45384348|ref|NP_990652.1| glutamic-oxaloacetic transamin... 322 2e-86
gi|156554459|ref|XP_001601449.1| PREDICTED: similar to ENSA... 322 2e-86
gi|158291516|ref|XP_313023.3| AGAP004142-PA [Anopheles gamb... 321 5e-86
gi|81074221|gb|ABB55364.1| aspartate aminotransferase-like ... 321 6e-86
gi|170042974|ref|XP_001849180.1| conserved hypothetical pro... 320 1e-85
gi|118488006|gb|ABK95824.1| unknown [Populus trichocarpa] 319 2e-85
gi|25009816|gb|AAN71079.1| AT16867p [Drosophila melanogaster] 319 2e-85
gi|91083103|ref|XP_969549.1| PREDICTED: similar to Aspartat... 319 2e-85
gi|24654046|ref|NP_725534.1| Glutamate oxaloacetate transam... 319 3e-85
gi|157829772|pdb|1AAT|A Chain A, Oxoglutarate-Induced Confo... 318 3e-85
gi|33286231|gb|AAQ01663.1| aminotransferase [Drosophila mel... 318 3e-85
gi|19922362|ref|NP_611086.1| Glutamate oxaloacetate transam... 318 4e-85
gi|121715326|ref|XP_001275272.1| aspartate transaminase, pu... 318 4e-85
gi|47522636|ref|NP_999092.1| cytosolic aspartate aminotrans... 318 6e-85
gi|47207664|emb|CAF94552.1| unnamed protein product [Tetrao... 318 6e-85
gi|58262008|ref|XP_568414.1| aspartate aminotransferase mit... 318 6e-85
gi|633095|dbj|BAA08106.1| plastidic aspartate aminotransfer... 317 8e-85
gi|71004152|ref|XP_756742.1| hypothetical protein UM00595.1... 317 1e-84
gi|47085773|ref|NP_998222.1| glutamic-oxaloacetic transamin... 317 1e-84
gi|47212010|emb|CAF89854.1| unnamed protein product [Tetrao... 316 2e-84
gi|159129380|gb|EDP54494.1| aspartate transaminase, putativ... 316 2e-84
gi|119480857|ref|XP_001260457.1| aspartate transaminase, pu... 316 2e-84
gi|169844081|ref|XP_001828762.1| hypothetical protein CC1G_... 316 2e-84
gi|121707701|ref|XP_001271915.1| aspartate aminotransferase... 316 2e-84
gi|71001234|ref|XP_755298.1| aspartate transaminase [Asperg... 315 3e-84
gi|62858411|ref|NP_001016933.1| glutamic-oxaloacetic transa... 315 3e-84
gi|157745241|ref|XP_001667717.1| Hypothetical protein CBG22... 315 3e-84
gi|46138463|ref|XP_390922.1| hypothetical protein FG10746.1... 315 3e-84
gi|168324|gb|AAA33408.1| aspartate aminotransferase P1 315 4e-84
gi|388896|gb|AAA50160.1| aspartate aminotransferase P1 315 4e-84
gi|2506178|sp|P28011|AAT1_MEDSA Aspartate aminotransferase ... 314 6e-84
gi|531555|emb|CAA56932.1| aspartate aminotransferase [Arabi... 314 6e-84
gi|15236129|ref|NP_194927.1| ASP5 (ASPARTATE AMINOTRANSFERA... 314 6e-84
gi|125541475|gb|EAY87870.1| hypothetical protein OsI_009103... 314 7e-84
gi|19571|emb|CAA43779.1| aspartate aminotransferase [Medica... 314 7e-84
gi|79326077|ref|NP_001031767.1| ASP5 (ASPARTATE AMINOTRANSF... 314 9e-84
gi|21618222|gb|AAM67272.1| aspartate aminotransferase [Arab... 313 1e-83
gi|119500436|ref|XP_001266975.1| aspartate aminotransferase... 313 1e-83
gi|170040614|ref|XP_001848088.1| aspartate aminotransferase... 313 1e-83
gi|2392158|pdb|1AJS|A Chain A, Refinement And Comparison Of... 313 1e-83
gi|46136447|ref|XP_389915.1| hypothetical protein FG09739.1... 313 1e-83
gi|57107513|ref|XP_543963.1| PREDICTED: similar to aspartat... 313 1e-83
gi|115449235|ref|NP_001048397.1| Os02g0797500 [Oryza sativa... 313 1e-83
gi|29468084|gb|AAO23563.1| aspartate aminotransferase [Oryz... 313 1e-83
gi|693690|gb|AAA79370.1| aspartate aminotransferase 313 1e-83
gi|2654095|gb|AAC50015.1| aspartate aminotransferase cytoso... 313 1e-83
gi|223208|prf||0608196A aminotransferase,Asp 313 2e-83
gi|15239772|ref|NP_197456.1| ASP2 (ASPARTATE AMINOTRANSFERA... 313 2e-83
gi|147903225|ref|NP_001080543.1| Aspartate aminotransferase... 313 2e-83
gi|122065117|sp|P33097|AATC_BOVIN Aspartate aminotransferas... 312 3e-83
gi|157339753|emb|CAO44294.1| unnamed protein product [Vitis... 312 3e-83
gi|148727355|ref|NP_001092011.1| glutamic-oxaloacetic trans... 312 3e-83
gi|147766607|emb|CAN76227.1| hypothetical protein [Vitis vi... 312 3e-83
gi|112972|sp|P28734|AATC_DAUCA Aspartate aminotransferase, ... 312 4e-83
gi|584706|sp|P37833|AATC_ORYSJ Aspartate aminotransferase, ... 311 4e-83
gi|15239078|ref|NP_196713.1| ASP3 (ASPARTATE AMINOTRANSFERA... 311 5e-83
gi|2392156|pdb|1AJR|A Chain A, Refinement And Comparison Of... 311 5e-83
gi|67523073|ref|XP_659597.1| hypothetical protein AN1993.2 ... 311 5e-83
gi|75076072|sp|Q4R5L1|AATC_MACFA Aspartate aminotransferase... 311 5e-83
gi|2654094|gb|AAC50014.1| aspartate aminotransferase glyoxy... 311 5e-83
gi|4504067|ref|NP_002070.1| aspartate aminotransferase 1 [H... 311 6e-83
gi|47498070|ref|NP_998829.1| glutamic-oxaloacetic transamin... 311 7e-83
gi|145514736|ref|XP_001443273.1| hypothetical protein GSPAT... 311 7e-83
gi|20597|emb|CAA45022.1| aspartate aminotransferase [Panicu... 311 8e-83
gi|149689774|ref|XP_001501094.1| PREDICTED: similar to Aspa... 310 8e-83
gi|145514083|ref|XP_001442952.1| hypothetical protein GSPAT... 310 9e-83
gi|75041219|sp|Q5R691|AATC_PONPY Aspartate aminotransferase... 310 1e-82
gi|168068005|ref|XP_001785888.1| predicted protein [Physcom... 310 1e-82
gi|126273073|ref|XP_001373225.1| PREDICTED: similar to Glut... 310 1e-82
gi|59858077|gb|AAX08873.1| aspartate aminotransferase 1 [Bo... 310 1e-82
>gi|71747120|ref|XP_822615.1| aspartate aminotransferase [Trypanosoma brucei TREU927]
gi|14915801|gb|AAK73815.1|AF326989_1 aspartate aminotransferase [Trypanosoma brucei]
gi|70832283|gb|EAN77787.1| aspartate aminotransferase [Trypanosoma brucei]
Length = 403
Score = 755 bits (1950), Expect = 0.0, Method: Composition-based stats.
Identities = 372/403 (92%), Positives = 372/403 (92%)
Query: 1 MSRPFKDLAPVPLDPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVD 60
MSRPFKDLAPVPLDPVFGL DLVIGAYRDQNGLPYPLKVVRKAERRIVD
Sbjct: 1 MSRPFKDLAPVPLDPVFGLARAAKAAPEPKADLVIGAYRDQNGLPYPLKVVRKAERRIVD 60
Query: 61 MGLDKEYPPMTGLLNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVVPED 120
MGLDKEYPPMTGLLNFVEEAVKLAYGNTVPLERI RQVVPED
Sbjct: 61 MGLDKEYPPMTGLLNFVEEAVKLAYGNTVPLERIAASQGLSGTGSLSLGATLLRQVVPED 120
Query: 121 TPVYVSNPTWSNHVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHA 180
TPVYVSNPTWSNHVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHA
Sbjct: 121 TPVYVSNPTWSNHVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHA 180
Query: 181 CAHNPTGVDPSKDQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEM 240
CAHNPTGVDPSKDQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEM
Sbjct: 181 CAHNPTGVDPSKDQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEM 240
Query: 241 LLAQSFSKNMGLYAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVM 300
LLAQSFSKNMGLYAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVM
Sbjct: 241 LLAQSFSKNMGLYAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVM 300
Query: 301 SDKELRAEWEQELKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQC 360
SDKELRAEWEQELKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQC
Sbjct: 301 SDKELRAEWEQELKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQC 360
Query: 361 ERLCEKRVFVLPVGRANLAALTPSTMDFLVKSIDDVVRHVRNK 403
ERLCEKRVFVLPVGRANLAALTPSTMDFLVKSIDDVVRHVRNK
Sbjct: 361 ERLCEKRVFVLPVGRANLAALTPSTMDFLVKSIDDVVRHVRNK 403
>gi|71404025|ref|XP_804756.1| aspartate aminotransferase, putative [Trypanosoma cruzi strain CL
Brener]
gi|70867885|gb|EAN82905.1| aspartate aminotransferase, putative [Trypanosoma cruzi]
Length = 404
Score = 481 bits (1238), Expect = e-134, Method: Composition-based stats.
Identities = 224/396 (56%), Positives = 290/396 (73%)
Query: 5 FKDLAPVPLDPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLD 64
+ ++A +P DP+F DL+IGAYRD G PYPL VVRKAE+R+++M +D
Sbjct: 7 WNNIAALPADPIFSASLVAKNAPEPKVDLIIGAYRDAEGHPYPLHVVRKAEQRLLEMNVD 66
Query: 65 KEYPPMTGLLNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVVPEDTPVY 124
KEY PM+G F+EE++K+AYG++V E + +V+ TPVY
Sbjct: 67 KEYLPMSGYAPFIEESLKIAYGDSVARENVVGVQGLSGTGSLSIGACFLARVLSPKTPVY 126
Query: 125 VSNPTWSNHVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHN 184
+S+PTW NH ++ ++R+YRYY + +DF GL+EDLNVAP+GSI++LHACAHN
Sbjct: 127 ISDPTWPNHYAVMAAANLTDLRKYRYYDSAKRCIDFDGLLEDLNVAPEGSIVILHACAHN 186
Query: 185 PTGVDPSKDQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQ 244
PTG+DP+ +QWA I +VF R+LIPFFDSAYQG+A+GSLD DAY+IR FA++GMEMLLAQ
Sbjct: 187 PTGMDPTHEQWAKILEVFQARRLIPFFDSAYQGYATGSLDNDAYSIRLFARQGMEMLLAQ 246
Query: 245 SFSKNMGLYAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKE 304
S+SKNMGLYAERVGV S V +D + ++S+LE I RS YSTPP HGAR+A+LV+SD E
Sbjct: 247 SYSKNMGLYAERVGVCSVVTADPKKAPLIKSQLETIVRSQYSTPPAHGARVAYLVLSDSE 306
Query: 305 LRAEWEQELKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLC 364
LRA WEQEL+ M RV MRQ +Y+GL +LGTPG+WEHII Q GMFSY+GL++ QCE+L
Sbjct: 307 LRAGWEQELRVMSTRVLEMRQALYDGLKRLGTPGSWEHIIQQVGMFSYLGLTKTQCEKLI 366
Query: 365 EKRVFVLPVGRANLAALTPSTMDFLVKSIDDVVRHV 400
E+RVFVLP GRAN+A LT T++ LVK IDDVVR V
Sbjct: 367 ERRVFVLPSGRANMAGLTKRTVELLVKGIDDVVRTV 402
>gi|71411043|ref|XP_807788.1| aspartate aminotransferase, putative [Trypanosoma cruzi strain CL
Brener]
gi|70871862|gb|EAN85937.1| aspartate aminotransferase, putative [Trypanosoma cruzi]
Length = 404
Score = 476 bits (1224), Expect = e-132, Method: Composition-based stats.
Identities = 221/396 (55%), Positives = 289/396 (72%)
Query: 5 FKDLAPVPLDPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLD 64
+ ++A +P DP+F DL+IGAYRD G PYPL VVRKAE+R+++M D
Sbjct: 7 WNNIAALPADPIFSASLVAKKAPEPKADLIIGAYRDAEGHPYPLNVVRKAEQRLLEMNAD 66
Query: 65 KEYPPMTGLLNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVVPEDTPVY 124
KEY PM+G F+EE++K+AYG++V E + +V+ DTPVY
Sbjct: 67 KEYLPMSGYAPFIEESLKIAYGDSVARENVVGIQGLSGTGSLSIGACFLARVLSRDTPVY 126
Query: 125 VSNPTWSNHVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHN 184
+S+PTW NH ++ ++R+YRYY + +DF GL+EDLN AP+GSI++LHACAHN
Sbjct: 127 ISDPTWPNHYAVMAAANLTDLRKYRYYDNAKRCIDFDGLLEDLNGAPEGSIVILHACAHN 186
Query: 185 PTGVDPSKDQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQ 244
PTG+DP+ +QWA I +VF R+LIPFFDSAYQG+A+GSLD DAY+IR FA++GMEMLLAQ
Sbjct: 187 PTGMDPTHEQWAKILEVFQARRLIPFFDSAYQGYATGSLDNDAYSIRLFARQGMEMLLAQ 246
Query: 245 SFSKNMGLYAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKE 304
S+SKNMGLYAERVGV S V ++ + ++S+LE I RS YSTPP HGAR+A+LV+SD E
Sbjct: 247 SYSKNMGLYAERVGVCSIVTANPKKAPLIKSQLETIVRSQYSTPPAHGARVAYLVLSDPE 306
Query: 305 LRAEWEQELKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLC 364
LRA WEQEL+ M RV MRQ +Y+GL +LGTPG+WEHII Q GMFSY+GL++ QCE+L
Sbjct: 307 LRAGWEQELRVMSTRVLEMRQALYDGLKRLGTPGSWEHIIQQVGMFSYLGLTKAQCEKLI 366
Query: 365 EKRVFVLPVGRANLAALTPSTMDFLVKSIDDVVRHV 400
E+RVFVLP GRAN+A LT +++ LVK ID+VVR V
Sbjct: 367 ERRVFVLPSGRANMAGLTKRSVELLVKGIDEVVRTV 402
>gi|14915799|gb|AAK73814.1|AF326988_1 aspartate aminotransferase [Crithidia fasciculata]
Length = 405
Score = 429 bits (1103), Expect = e-118, Method: Composition-based stats.
Identities = 206/397 (51%), Positives = 266/397 (67%), Gaps = 1/397 (0%)
Query: 5 FKDLAPVPLDPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLD 64
F L+ +P D +F DL+IGAYRD++G PYPLK VRKAER ++DM LD
Sbjct: 9 FDGLSALPPDSIFFTSQKAKAAQGPKADLIIGAYRDEHGCPYPLKTVRKAERILLDMNLD 68
Query: 65 KEYPPMTGLLNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPV 123
EY PMTG FV+EA K+ Y ++V + + +V P+ TP+
Sbjct: 69 YEYLPMTGYKPFVDEATKIIYADSVAPDHLVAVQTLSGTGAVYLGAAFLAEVYDPKTTPI 128
Query: 124 YVSNPTWSNHVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAH 183
Y+ NPTW NH SI + G K+IR Y YY P T LDF G+ +D+ AP+ S+ +LH CAH
Sbjct: 129 YLPNPTWPNHPSILKLTGWKDIRTYNYYDPKTVALDFEGIKKDIQEAPECSVFLLHQCAH 188
Query: 184 NPTGVDPSKDQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLA 243
NPTGVDPS QW IAD+ + +K FFDSAYQG+ASGSLDEDA+A R F K+G++ +LA
Sbjct: 189 NPTGVDPSHAQWEEIADLMLAKKHQVFFDSAYQGYASGSLDEDAFAARLFVKKGVQFILA 248
Query: 244 QSFSKNMGLYAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDK 303
QSFSKNMGLY ER G +S V+ + R AV++ L+++ R+ YS PP HGAR+ HLV+SDK
Sbjct: 249 QSFSKNMGLYNERTGTLSVVLRNPERAAAVKTHLDLLIRANYSNPPAHGARLVHLVLSDK 308
Query: 304 ELRAEWEQELKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERL 363
ELR EWE EL EM NR+R+MR VY+ L +LGTPGTWEHIINQ GMFS++GLS+ QC+
Sbjct: 309 ELRKEWEAELAEMANRIRTMRHTVYDELKRLGTPGTWEHIINQIGMFSFLGLSKEQCQYC 368
Query: 364 CEKRVFVLPVGRANLAALTPSTMDFLVKSIDDVVRHV 400
+ VF+L GRAN+A LT T L ++ID+ VR V
Sbjct: 369 QDHNVFILLSGRANMAGLTHDTALMLARTIDEAVRTV 405
>gi|154344503|ref|XP_001568193.1| aspartate aminotransferase, putative [Leishmania braziliensis
MHOM/BR/75/M2904]
gi|134065530|emb|CAM43298.1| aspartate aminotransferase, putative [Leishmania braziliensis]
Length = 409
Score = 417 bits (1071), Expect = e-115, Method: Composition-based stats.
Identities = 197/386 (51%), Positives = 262/386 (67%), Gaps = 1/386 (0%)
Query: 14 DPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGL 73
D +FGL +LVIGAYRD NG+PYPL+VVRKAER ++DM D EY P++G
Sbjct: 22 DAIFGLAKRAAAAKGPKANLVIGAYRDDNGIPYPLRVVRKAERLLIDMNPDYEYLPISGY 81
Query: 74 LNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSN 132
F++EAVK+ YG+ V LE + V E TP+Y+SNPTW N
Sbjct: 82 QPFIDEAVKMVYGDAVELENLVAVQSLSGTGALSLGAKLLTYVYDAEKTPIYLSNPTWPN 141
Query: 133 HVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSK 192
H SI G KNI Y YY P T L+F G+ +D+ AP GS+ +LH CAHNPTGVDPS+
Sbjct: 142 HNSIVKGAGWKNIHTYTYYDPKTVSLNFEGMKKDIQAAPNGSVFILHQCAHNPTGVDPSQ 201
Query: 193 DQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGL 252
+QW IA++ + + FFDSAYQG+ASG+LDEDAYA+R FA+RG+E+LLAQSFSKNMGL
Sbjct: 202 EQWDEIAELMLAKHHQVFFDSAYQGYASGNLDEDAYAVRLFARRGIEVLLAQSFSKNMGL 261
Query: 253 YAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQE 312
Y ER G +S ++ + ++ V+S LE + RS Y+ PP HGAR+ HL++S+ ELR EWE E
Sbjct: 262 YNERTGTLSLLLKNKTKCADVKSVLESLIRSEYTCPPAHGARLVHLILSNSELRKEWEVE 321
Query: 313 LKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLP 372
L M R+R+MR+ VY+ L++L TPG+WEH+INQ GMFS++GLS+ +C+ + VF+
Sbjct: 322 LAAMAERIRTMRRIVYDELLRLQTPGSWEHVINQIGMFSFLGLSKERCQYCQDHNVFITL 381
Query: 373 VGRANLAALTPSTMDFLVKSIDDVVR 398
GRAN+AALT T L ++I+D VR
Sbjct: 382 TGRANMAALTHETALLLAQTINDAVR 407
>gi|84619611|emb|CAF06209.1| aspartate aminotransferase [Leishmania donovani]
gi|84619613|emb|CAF06210.1| aspartate aminotransferase [Leishmania donovani]
gi|84619619|emb|CAF06213.1| aspartate aminotransferase [Leishmania donovani]
gi|84619625|emb|CAF06216.1| aspartate aminotransferase [Leishmania donovani]
gi|84619627|emb|CAF06217.1| aspartate aminotransferase [Leishmania donovani]
gi|84619647|emb|CAF06227.1| aspartate aminotransferase [Leishmania donovani]
gi|84619649|emb|CAF06228.1| aspartate aminotransferase [Leishmania donovani]
gi|84619651|emb|CAF06229.1| aspartate aminotransferase [Leishmania donovani]
gi|84619655|emb|CAF06231.1| aspartate aminotransferase [Leishmania donovani]
gi|84619657|emb|CAF06232.1| aspartate aminotransferase [Leishmania donovani]
gi|84619659|emb|CAF06233.1| aspartate aminotransferase [Leishmania donovani]
gi|84619661|emb|CAF06234.1| aspartate aminotransferase [Leishmania donovani]
gi|84619663|emb|CAF06235.1| aspartate aminotransferase [Leishmania donovani]
gi|109450658|emb|CAJ40951.1| aspartate aminotransferase [Leishmania donovani]
gi|109450662|emb|CAJ40953.1| aspartate aminotransferase [Leishmania donovani]
gi|109450768|emb|CAJ43254.1| aspartate aminotransferase [Leishmania donovani]
Length = 412
Score = 415 bits (1067), Expect = e-114, Method: Composition-based stats.
Identities = 196/388 (50%), Positives = 262/388 (67%), Gaps = 1/388 (0%)
Query: 14 DPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGL 73
D +F L +LVIGAYRD+ G PYPL+VVRKAER ++DM LD EY P++G
Sbjct: 22 DVIFDLAKRAAAAKGPKANLVIGAYRDEQGRPYPLRVVRKAERLLLDMNLDYEYLPISGY 81
Query: 74 LNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSN 132
F++EAVK+ YG+TV LE + +V E TP+Y+S+PTW N
Sbjct: 82 QPFIDEAVKMIYGDTVALENLVAVQTLSGTGAVSLGAKLLTRVFDAEKTPIYLSDPTWPN 141
Query: 133 HVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSK 192
H I G KNI Y YY P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS+
Sbjct: 142 HYGIVKAAGWKNICTYAYYDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQ 201
Query: 193 DQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGL 252
+QW IA + + ++ FFDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGL
Sbjct: 202 EQWDEIASLMLAKRHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGL 261
Query: 253 YAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQE 312
Y+ER G +S ++ D +++ V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE E
Sbjct: 262 YSERAGTLSLLLKDKTKRADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAE 321
Query: 313 LKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLP 372
L M R+R+MR+ VY+ L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+
Sbjct: 322 LSAMAERIRTMRRTVYDELLRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITL 381
Query: 373 VGRANLAALTPSTMDFLVKSIDDVVRHV 400
GRAN+A LT T L ++I+D VR+V
Sbjct: 382 SGRANMAGLTHETALMLAQTINDAVRNV 409
>gi|84619665|emb|CAF06236.1| aspartate aminotransferase [Leishmania gerbilli]
Length = 408
Score = 414 bits (1065), Expect = e-114, Method: Composition-based stats.
Identities = 195/387 (50%), Positives = 259/387 (66%), Gaps = 1/387 (0%)
Query: 14 DPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGL 73
D +F L +LVIGAYRD+ G PYPL+VVRKAE+ ++DM LD EY P++G
Sbjct: 22 DAIFDLAKRAAAAKGPKANLVIGAYRDEQGRPYPLRVVRKAEQLLLDMNLDYEYLPISGY 81
Query: 74 LNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSN 132
F++EAVK+ YG+TV LE + V E TP+Y+SNPTW N
Sbjct: 82 QPFIDEAVKIIYGDTVELENLVAVQTLSGTGAVSLGAKLLTHVFDAEKTPIYLSNPTWLN 141
Query: 133 HVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSK 192
H I G KNI Y YY P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS+
Sbjct: 142 HYGIVKAAGWKNICTYAYYDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQ 201
Query: 193 DQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGL 252
+QW IA + + + FFDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGL
Sbjct: 202 EQWDEIASLMLAKHHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGL 261
Query: 253 YAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQE 312
Y+ER G +S ++ D +++ V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE E
Sbjct: 262 YSERAGTLSLLLKDKTKRADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAE 321
Query: 313 LKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLP 372
L M R+R+MR+ VY+ L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+
Sbjct: 322 LSAMAERIRTMRRTVYDELLRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITV 381
Query: 373 VGRANLAALTPSTMDFLVKSIDDVVRH 399
GRAN+A LT T L ++I+D VR+
Sbjct: 382 SGRANMAGLTHETALMLAQTINDAVRN 408
>gi|46852001|gb|AAT02697.1| glutamate oxaloacetate [Leishmania donovani]
gi|46852003|gb|AAT02698.1| glutamate oxaloacetate [Leishmania donovani]
gi|46852007|gb|AAT02700.1| glutamate oxaloacetate [Leishmania donovani]
gi|46852013|gb|AAT02703.1| glutamate oxaloacetate [Leishmania donovani]
gi|46852015|gb|AAT02704.1| glutamate oxaloacetate [Leishmania donovani]
gi|46852019|gb|AAT02706.1| glutamate oxaloacetate [Leishmania donovani]
Length = 373
Score = 414 bits (1063), Expect = e-114, Method: Composition-based stats.
Identities = 193/370 (52%), Positives = 258/370 (69%), Gaps = 1/370 (0%)
Query: 32 DLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGLLNFVEEAVKLAYGNTVPL 91
+LVIGAYRD+ G PYPL+VVRKAER ++DM LD EY P++G F++EAVK+ YG+TV L
Sbjct: 1 NLVIGAYRDEQGRPYPLRVVRKAERLLLDMNLDYEYLPISGYQPFIDEAVKMIYGDTVAL 60
Query: 92 ERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSNHVSIFGIVGHKNIREYRY 150
E + +V E TP+Y+S+PTW NH I G KNI Y Y
Sbjct: 61 ENLVAVQTLSGTGAVSLGAKLLTRVFDAEKTPIYLSDPTWPNHYGIVKAAGWKNICTYAY 120
Query: 151 YSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSKDQWATIADVFVERKLIPF 210
Y P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS++QW IA + + ++ F
Sbjct: 121 YDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQEQWDEIASLMLAKRHQVF 180
Query: 211 FDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGLYAERVGVISAVVSDASRK 270
FDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGLY+ER G +S ++ D +++
Sbjct: 181 FDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKDKTKR 240
Query: 271 EAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQELKEMVNRVRSMRQGVYEG 330
V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE EL M R+R+MR+ VY+
Sbjct: 241 ADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDE 300
Query: 331 LMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLPVGRANLAALTPSTMDFLV 390
L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+ GRAN+A LT T L
Sbjct: 301 LLRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITLSGRANMAGLTHETALMLA 360
Query: 391 KSIDDVVRHV 400
++I+D VR+V
Sbjct: 361 QTINDAVRNV 370
>gi|33311168|gb|AAQ03600.1|AF416601_1 broad specificity aminotransferase [Leishmania mexicana]
Length = 412
Score = 414 bits (1063), Expect = e-114, Method: Composition-based stats.
Identities = 195/388 (50%), Positives = 263/388 (67%), Gaps = 1/388 (0%)
Query: 14 DPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGL 73
DP+F L +LVIGAYRD+ GLPYPL+VVRKAE+ ++DM L+ EY P++G
Sbjct: 22 DPIFELAKRAAAAKGPKANLVIGAYRDEQGLPYPLRVVRKAEQLLLDMNLNYEYLPISGY 81
Query: 74 LNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSN 132
F++EAVK+ YG+TV LE + V E TP+Y+++PTW N
Sbjct: 82 QPFIDEAVKMTYGDTVELENLVAVQTLSGTGALSLGAKLLTHVFDAEKTPIYLADPTWPN 141
Query: 133 HVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSK 192
H SI G K+IR Y YY T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS+
Sbjct: 142 HYSIVKAAGWKDIRTYAYYDHKTLGLDFEGMKKDILAAPDGSVFLLHQCAHNPTGVDPSQ 201
Query: 193 DQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGL 252
+QW IA + + + FFDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGL
Sbjct: 202 EQWNEIASLMLAKHHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGL 261
Query: 253 YAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQE 312
Y+ER G +S ++ D +++ V+S ++ + R+ Y+ PP HGAR+AHL++S+ ELR EWE E
Sbjct: 262 YSERAGTLSLLLKDKTKRADVKSVMDSLIRAEYTCPPAHGARLAHLILSNNELRKEWEAE 321
Query: 313 LKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLP 372
L M R+R+MR+ VY+ L++L TPG WEH+INQ GMFS++GLS+ QCE +F+
Sbjct: 322 LSAMAERIRTMRRTVYDELLRLQTPGRWEHVINQIGMFSFLGLSKEQCEYCQNHNIFITL 381
Query: 373 VGRANLAALTPSTMDFLVKSIDDVVRHV 400
GRAN+A LT T L ++I+D VR+V
Sbjct: 382 SGRANIAGLTHETALMLAQTINDAVRNV 409
>gi|46852005|gb|AAT02699.1| glutamate oxaloacetate [Leishmania donovani]
Length = 373
Score = 413 bits (1062), Expect = e-113, Method: Composition-based stats.
Identities = 193/370 (52%), Positives = 258/370 (69%), Gaps = 1/370 (0%)
Query: 32 DLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGLLNFVEEAVKLAYGNTVPL 91
+LVIGAYRD+ G PYPL+VVRKAER ++DM LD EY P++G F++EAVK+ YG+TV L
Sbjct: 1 NLVIGAYRDEQGRPYPLRVVRKAERLLLDMNLDYEYLPISGYQPFIDEAVKMIYGDTVAL 60
Query: 92 ERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSNHVSIFGIVGHKNIREYRY 150
E + +V E TP+Y+S+PTW NH I G KNI Y Y
Sbjct: 61 ENLVAVQTLSGTGAVSLGAKLLTRVFDAEKTPIYLSDPTWPNHYGIVKAAGWKNICTYAY 120
Query: 151 YSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSKDQWATIADVFVERKLIPF 210
Y P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS++QW IA + + ++ F
Sbjct: 121 YDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQEQWDEIASLMLAKRHQVF 180
Query: 211 FDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGLYAERVGVISAVVSDASRK 270
FDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGLY+ER G +S ++ D +++
Sbjct: 181 FDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKDKTKR 240
Query: 271 EAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQELKEMVNRVRSMRQGVYEG 330
V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE EL M R+R+MR+ VY+
Sbjct: 241 ADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDE 300
Query: 331 LMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLPVGRANLAALTPSTMDFLV 390
L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+ GRAN+A LT T L
Sbjct: 301 LLRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITLSGRANVAGLTHETALMLA 360
Query: 391 KSIDDVVRHV 400
++I+D VR+V
Sbjct: 361 QTINDAVRNV 370
>gi|109450666|emb|CAJ40955.1| aspartate aminotransferase [Leishmania arabica]
Length = 412
Score = 413 bits (1061), Expect = e-113, Method: Composition-based stats.
Identities = 195/388 (50%), Positives = 259/388 (66%), Gaps = 1/388 (0%)
Query: 14 DPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGL 73
D +F L +LVIGAYRD+ G PYPL+VVRKAE+ ++DM LD EY P++G
Sbjct: 22 DAIFDLAKRAAAAKGPKANLVIGAYRDEQGRPYPLRVVRKAEQLLLDMNLDYEYLPISGY 81
Query: 74 LNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSN 132
F++EAVK+ YG+TV LE + V E TP+Y+SNPTW N
Sbjct: 82 QPFIDEAVKIIYGDTVELENLVAVQTLSGTGAVSLGAKLLTHVFDAEKTPIYLSNPTWPN 141
Query: 133 HVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSK 192
H I G KNI Y YY P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS+
Sbjct: 142 HYGIVKAAGWKNICTYAYYDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQ 201
Query: 193 DQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGL 252
+QW IA + + + FFDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGL
Sbjct: 202 EQWDEIASLMLAKHHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGL 261
Query: 253 YAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQE 312
Y+ER G +S ++ D +++ V+S ++ + R Y+ PP HGAR+A L++S+ ELR EWE E
Sbjct: 262 YSERAGTLSLLLKDKTKRADVKSVMDSLIRGEYTCPPAHGARLAQLILSNNELRKEWEAE 321
Query: 313 LKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLP 372
L M R+R+MR+ VY+ L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+
Sbjct: 322 LSAMAERIRTMRRTVYDELLRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITV 381
Query: 373 VGRANLAALTPSTMDFLVKSIDDVVRHV 400
GRAN+A LT T L ++I+D VR+V
Sbjct: 382 SGRANMAGLTHETALMLAQTINDAVRNV 409
>gi|72547196|ref|XP_843191.1| aspartate aminotransferase, putative [Leishmania major strain
Friedlin]
gi|70905670|gb|AAZ14309.1| aspartate aminotransferase, putative [Leishmania major strain
Friedlin]
gi|109450664|emb|CAJ40954.1| aspartate aminotransferase [Leishmania major]
Length = 412
Score = 412 bits (1059), Expect = e-113, Method: Composition-based stats.
Identities = 194/388 (50%), Positives = 261/388 (67%), Gaps = 1/388 (0%)
Query: 14 DPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGL 73
D +F L +LVIGAYRD+ G PYPL+VVRKAE+ ++DM LD EY P++G
Sbjct: 22 DVIFDLAKRAAAAKGPKANLVIGAYRDEQGRPYPLRVVRKAEQLLLDMNLDYEYLPISGY 81
Query: 74 LNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSN 132
F++EAVK+ YGNTV LE + +V E TP+Y+S+PTW N
Sbjct: 82 QPFIDEAVKIIYGNTVELENLVAVQTLSGTGAVSLGAKLLTRVFDAETTPIYLSDPTWPN 141
Query: 133 HVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSK 192
H + G KNI Y YY P T L+F G+ +D+ AP GS+ +LH CAHNPTGVDPS+
Sbjct: 142 HYGVVKAAGWKNICTYAYYDPKTVSLNFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQ 201
Query: 193 DQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGL 252
+QW IA + + + FFDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGL
Sbjct: 202 EQWNEIASLMLAKHHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGL 261
Query: 253 YAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQE 312
Y+ER G +S ++ D +++ V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE E
Sbjct: 262 YSERAGTLSLLLKDKTKRADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAE 321
Query: 313 LKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLP 372
L M R+R+MR+ VY+ L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+
Sbjct: 322 LSAMAERIRTMRRTVYDELLRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITV 381
Query: 373 VGRANLAALTPSTMDFLVKSIDDVVRHV 400
GRAN+A LT T L ++I+D VR+V
Sbjct: 382 SGRANMAGLTHETALMLAQTINDAVRNV 409
>gi|146100586|ref|XP_001468898.1| aspartate aminotransferase [Leishmania infantum]
gi|84619605|emb|CAF06206.1| aspartate aminotransferase [Leishmania infantum]
gi|84619607|emb|CAF06207.1| aspartate aminotransferase [Leishmania infantum]
gi|84619609|emb|CAF06208.1| aspartate aminotransferase [Leishmania infantum]
gi|84619617|emb|CAF06212.1| aspartate aminotransferase [Leishmania donovani]
gi|84619621|emb|CAF06214.1| aspartate aminotransferase [Leishmania infantum]
gi|84619623|emb|CAF06215.1| aspartate aminotransferase [Leishmania infantum]
gi|84619629|emb|CAF06218.1| aspartate aminotransferase [Leishmania donovani]
gi|84619631|emb|CAF06219.1| aspartate aminotransferase [Leishmania infantum]
gi|84619633|emb|CAF06220.1| aspartate aminotransferase [Leishmania infantum]
gi|84619635|emb|CAF06221.1| aspartate aminotransferase [Leishmania infantum]
gi|84619637|emb|CAF06222.1| aspartate aminotransferase [Leishmania infantum]
gi|84619639|emb|CAF06223.1| aspartate aminotransferase [Leishmania donovani]
gi|84619645|emb|CAF06226.1| aspartate aminotransferase [Leishmania infantum]
gi|84619653|emb|CAF06230.1| aspartate aminotransferase [Leishmania donovani]
gi|109450654|emb|CAJ40949.1| aspartate aminotransferase [Leishmania infantum]
gi|109450656|emb|CAJ40950.1| aspartate aminotransferase [Leishmania infantum]
gi|109450758|emb|CAJ43249.1| aspartate aminotransferase [Leishmania infantum]
gi|109450760|emb|CAJ43250.1| aspartate aminotransferase [Leishmania infantum]
gi|109450762|emb|CAJ43251.1| aspartate aminotransferase [Leishmania infantum]
gi|109450764|emb|CAJ43252.1| aspartate aminotransferase [Leishmania infantum]
gi|109450766|emb|CAJ43253.1| aspartate aminotransferase [Leishmania infantum]
gi|134073267|emb|CAM71991.1| aspartate aminotransferase, putative [Leishmania infantum]
Length = 412
Score = 411 bits (1057), Expect = e-113, Method: Composition-based stats.
Identities = 195/388 (50%), Positives = 261/388 (67%), Gaps = 1/388 (0%)
Query: 14 DPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGL 73
D +F L +LVIGAYRD+ G PYPL+VVRKAER ++DM LD EY P++G
Sbjct: 22 DVIFDLAKRAAAAKGPKANLVIGAYRDEQGRPYPLRVVRKAERLLLDMNLDYEYLPISGY 81
Query: 74 LNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSN 132
F++EAVK+ YG+TV LE + +V E TP+Y+S+PTW N
Sbjct: 82 QPFIDEAVKMIYGDTVALENLVAVQTLSGTGAVSLGAKLLTRVFDAEKTPIYLSDPTWPN 141
Query: 133 HVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSK 192
H I G KNI Y YY P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS+
Sbjct: 142 HYGIVKAAGWKNICTYAYYDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQ 201
Query: 193 DQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGL 252
+QW IA + + ++ FFDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGL
Sbjct: 202 EQWDEIASLMLAKRHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGL 261
Query: 253 YAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQE 312
Y+ER G +S ++ +++ V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE E
Sbjct: 262 YSERAGTLSLLLKYKTKRADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAE 321
Query: 313 LKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLP 372
L M R+R+MR+ VY+ L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+
Sbjct: 322 LSAMAERIRTMRRTVYDELLRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITL 381
Query: 373 VGRANLAALTPSTMDFLVKSIDDVVRHV 400
GRAN+A LT T L ++I+D VR+V
Sbjct: 382 SGRANMAGLTHETALMLAQTINDAVRNV 409
>gi|46852017|gb|AAT02705.1| glutamate oxaloacetate [Leishmania donovani]
Length = 373
Score = 411 bits (1057), Expect = e-113, Method: Composition-based stats.
Identities = 192/370 (51%), Positives = 257/370 (69%), Gaps = 1/370 (0%)
Query: 32 DLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGLLNFVEEAVKLAYGNTVPL 91
+LVIGAYRD+ G PYPL+VVRKAER ++DM LD EY P++G F++EAVK+ YG+TV L
Sbjct: 1 NLVIGAYRDEQGRPYPLRVVRKAERLLLDMNLDYEYLPISGYQPFIDEAVKMIYGDTVAL 60
Query: 92 ERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSNHVSIFGIVGHKNIREYRY 150
E + +V E TP+Y+S+PTW NH I G KNI Y Y
Sbjct: 61 ENLVAVQTLSGTGAVSLGAKLLTRVFDAEKTPIYLSDPTWPNHYGIVKAAGWKNICTYAY 120
Query: 151 YSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSKDQWATIADVFVERKLIPF 210
Y P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS++QW IA + + ++ F
Sbjct: 121 YDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQEQWDEIASLMLAKRHQVF 180
Query: 211 FDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGLYAERVGVISAVVSDASRK 270
F SAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGLY+ER G +S ++ D +++
Sbjct: 181 FGSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKDKTKR 240
Query: 271 EAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQELKEMVNRVRSMRQGVYEG 330
V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE EL M R+R+MR+ VY+
Sbjct: 241 ADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDE 300
Query: 331 LMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLPVGRANLAALTPSTMDFLV 390
L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+ GRAN+A LT T L
Sbjct: 301 LLRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITLSGRANMAGLTHETALMLA 360
Query: 391 KSIDDVVRHV 400
++I+D VR+V
Sbjct: 361 QTINDAVRNV 370
>gi|84619669|emb|CAF06238.1| aspartate aminotransferase [Leishmania aethiopica]
Length = 412
Score = 410 bits (1054), Expect = e-113, Method: Composition-based stats.
Identities = 193/388 (49%), Positives = 259/388 (66%), Gaps = 1/388 (0%)
Query: 14 DPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGL 73
D +F L +LVIGAYRD+ G PYPL+VVRKAE+ ++DM LD EY P++G
Sbjct: 22 DVIFDLAKRAAAAKGPKANLVIGAYRDEQGRPYPLRVVRKAEQLLLDMNLDYEYLPISGY 81
Query: 74 LNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSN 132
F++EAVK+ YG+ V LE + V E TP+Y+S+PTW+N
Sbjct: 82 QPFIDEAVKMIYGDAVELENLVAVQTLSGTGAVSLGAKLLTHVFDAEKTPIYLSDPTWAN 141
Query: 133 HVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSK 192
H I G KNI Y YY P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS+
Sbjct: 142 HYGIAKAAGWKNICTYAYYDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQ 201
Query: 193 DQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGL 252
+QW IA + + + FFDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGL
Sbjct: 202 EQWDEIASLMLAKYHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGL 261
Query: 253 YAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQE 312
Y+ER G +S ++ D +++ V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE E
Sbjct: 262 YSERAGTLSLLLKDKTKRADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAE 321
Query: 313 LKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLP 372
L M R+ +MR+ VY+ L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+
Sbjct: 322 LSAMAKRIHTMRRTVYDELLRLQTPGSWEHVINQTGMFSFLGLSKAQCEYCQSHNIFITL 381
Query: 373 VGRANLAALTPSTMDFLVKSIDDVVRHV 400
GRAN+A LT T L ++I+D VR+V
Sbjct: 382 SGRANMAGLTHETALMLAQTINDAVRNV 409
>gi|46852009|gb|AAT02701.1| glutamate oxaloacetate [Leishmania donovani]
gi|46852011|gb|AAT02702.1| glutamate oxaloacetate [Leishmania infantum]
gi|46852023|gb|AAT02708.1| glutamate oxaloacetate [Leishmania donovani]
Length = 373
Score = 410 bits (1054), Expect = e-112, Method: Composition-based stats.
Identities = 192/370 (51%), Positives = 257/370 (69%), Gaps = 1/370 (0%)
Query: 32 DLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGLLNFVEEAVKLAYGNTVPL 91
+LVIGAYRD+ G PYPL+VVRKAER ++DM LD EY P++G F++EAVK+ YG+TV L
Sbjct: 1 NLVIGAYRDEQGRPYPLRVVRKAERLLLDMNLDYEYLPISGYQPFIDEAVKMIYGDTVAL 60
Query: 92 ERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSNHVSIFGIVGHKNIREYRY 150
E + +V E TP+Y+S+PTW NH I G KNI Y Y
Sbjct: 61 ENLVAVQTLSGTGAVSLGAKLLTRVFDAEKTPIYLSDPTWPNHYGIVKAAGWKNICTYAY 120
Query: 151 YSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSKDQWATIADVFVERKLIPF 210
Y P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS++QW IA + + ++ F
Sbjct: 121 YDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQEQWDEIASLMLAKRHQVF 180
Query: 211 FDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGLYAERVGVISAVVSDASRK 270
FDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGLY+ER G +S ++ +++
Sbjct: 181 FDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKYKTKR 240
Query: 271 EAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQELKEMVNRVRSMRQGVYEG 330
V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE EL M R+R+MR+ VY+
Sbjct: 241 ADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDE 300
Query: 331 LMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLPVGRANLAALTPSTMDFLV 390
L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+ GRAN+A LT T L
Sbjct: 301 LLRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITLSGRANMAGLTHETALMLA 360
Query: 391 KSIDDVVRHV 400
++I+D VR+V
Sbjct: 361 QTINDAVRNV 370
>gi|84619667|emb|CAF06237.1| aspartate aminotransferase [Leishmania tropica]
Length = 412
Score = 410 bits (1053), Expect = e-112, Method: Composition-based stats.
Identities = 193/388 (49%), Positives = 258/388 (66%), Gaps = 1/388 (0%)
Query: 14 DPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGL 73
D +F L +LVIGAYRD+ G PYPL+VVRKAE+ ++DM LD EY P++G
Sbjct: 22 DVIFDLAKRAAAAKGPKANLVIGAYRDEQGRPYPLRVVRKAEQLLLDMNLDYEYLPISGY 81
Query: 74 LNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSN 132
F++EAVK+ Y + V LE + V E TP+Y+S+PTW N
Sbjct: 82 QPFIDEAVKMIYSDAVELENLVAVQTLSGTGAVSLGAKLLTHVFDAEKTPIYLSDPTWPN 141
Query: 133 HVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSK 192
H I G KNI Y YY P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS+
Sbjct: 142 HYGIVKAAGWKNICTYAYYDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQ 201
Query: 193 DQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGL 252
+QW IA + + + FFDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGL
Sbjct: 202 EQWDEIASLMLAKHHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGL 261
Query: 253 YAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQE 312
Y+ER G +S ++ D +++ V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE E
Sbjct: 262 YSERAGTLSLLLKDKTKRADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAE 321
Query: 313 LKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLP 372
L M R+R+MR+ VY+ L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+
Sbjct: 322 LSSMAERIRTMRRTVYDELLRLQTPGSWEHVINQTGMFSFLGLSKAQCEYCQNHNIFITX 381
Query: 373 VGRANLAALTPSTMDFLVKSIDDVVRHV 400
GRAN+A LT T L ++I+D VR+V
Sbjct: 382 SGRANMAGLTHETALMLAQTINDAVRNV 409
>gi|46852021|gb|AAT02707.1| glutamate oxaloacetate [Leishmania donovani]
Length = 373
Score = 406 bits (1044), Expect = e-111, Method: Composition-based stats.
Identities = 192/370 (51%), Positives = 256/370 (69%), Gaps = 1/370 (0%)
Query: 32 DLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGLLNFVEEAVKLAYGNTVPL 91
+LVIGAYRD+ G PYPL+VVRKAER ++DM LD EY P++G F++EAVK+ YG+TV L
Sbjct: 1 NLVIGAYRDEQGRPYPLRVVRKAERLLLDMNLDYEYLPISGYQPFIDEAVKMIYGDTVAL 60
Query: 92 ERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSNHVSIFGIVGHKNIREYRY 150
E + +V E TP+Y+S+PTW NH I G KNI Y Y
Sbjct: 61 ENLVAVQTLSGTGAVSLGAKLLTRVFDAEKTPIYLSDPTWPNHYGIVKAAGWKNICTYAY 120
Query: 151 YSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSKDQWATIADVFVERKLIPF 210
Y P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS++QW IA + + ++ F
Sbjct: 121 YDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQEQWDEIASLMLAKRHQVF 180
Query: 211 FDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGLYAERVGVISAVVSDASRK 270
FDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGLY+ER G +S ++ +++
Sbjct: 181 FDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGLYSERAGTLSLLLKYKTKR 240
Query: 271 EAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQELKEMVNRVRSMRQGVYEG 330
V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE EL M R+R+MR+ VY+
Sbjct: 241 ADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDE 300
Query: 331 LMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLPVGRANLAALTPSTMDFLV 390
L +L TPG+WEH+INQ GMFS++GLS+ QCE +F+ GRAN+A LT T L
Sbjct: 301 LPRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITLSGRANMADLTHETALMLA 360
Query: 391 KSIDDVVRHV 400
++I+D VR+V
Sbjct: 361 QTINDAVRNV 370
>gi|84619615|emb|CAF06211.1| aspartate aminotransferase [Leishmania donovani]
gi|84619641|emb|CAF06224.1| aspartate aminotransferase [Leishmania donovani]
gi|84619643|emb|CAF06225.1| aspartate aminotransferase [Leishmania donovani]
Length = 412
Score = 405 bits (1042), Expect = e-111, Method: Composition-based stats.
Identities = 195/388 (50%), Positives = 261/388 (67%), Gaps = 1/388 (0%)
Query: 14 DPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGL 73
D +F L +LVIGAYRD+ G PYPL+VVRKAER ++DM LD EY P++G
Sbjct: 22 DVIFDLAKRAAAAKGPKANLVIGAYRDEQGRPYPLRVVRKAERLLLDMNLDYEYLPISGY 81
Query: 74 LNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSN 132
F++EAVK+ YG+TV LE + +V E TP+Y+S+PTW N
Sbjct: 82 QPFIDEAVKMIYGDTVALENLVAVQTLSGTGAVSLGAKLLTRVFDAEKTPIYLSDPTWPN 141
Query: 133 HVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSK 192
H I G KNI Y YY P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS+
Sbjct: 142 HYGIVKAAGWKNICTYAYYDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQ 201
Query: 193 DQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGL 252
+QW IA + + ++ FFDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGL
Sbjct: 202 EQWDEIASLMLAKRHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGL 261
Query: 253 YAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQE 312
Y+ER G +S ++ +++ V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE E
Sbjct: 262 YSERAGTLSLLLKXKTKRADVKSVMDSLIREEYTCPPAHGARLAHLILSNNELRKEWEAE 321
Query: 313 LKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLP 372
L M R+R+MR+ VY+ L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+
Sbjct: 322 LSAMAERIRTMRRTVYDELLRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITL 381
Query: 373 VGRANLAALTPSTMDFLVKSIDDVVRHV 400
GRAN+A LT T L ++I+D VR+V
Sbjct: 382 SGRANMAGLTHETALMLAQTINDAVRNV 409
>gi|109450668|emb|CAJ40956.1| aspartate aminotransferase [Leishmania killicki]
Length = 412
Score = 405 bits (1041), Expect = e-111, Method: Composition-based stats.
Identities = 191/388 (49%), Positives = 256/388 (65%), Gaps = 1/388 (0%)
Query: 14 DPVFGLXXXXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGL 73
D +F L +LVIGAYRD+ G PYPL+VVRKAE+ ++DM LD EY P++G
Sbjct: 22 DVIFDLAKRAAAAKGPKANLVIGAYRDEQGRPYPLRVVRKAEQLLLDMNLDYEYLPISGY 81
Query: 74 LNFVEEAVKLAYGNTVPLERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSN 132
F++EAVK+ Y + V LE + V E TP+Y+S+PTW N
Sbjct: 82 QPFIDEAVKMIYSDAVELENLVAVQTLSGTGAVSLGAKLLTHVFDAEKTPIYLSDPTWPN 141
Query: 133 HVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSK 192
H I G KNI Y YY P T LDF G+ +D+ AP S+ +LH CAHNPTGVDPS+
Sbjct: 142 HYGIVKAAGWKNICTYAYYDPKTVSLDFEGMKKDILAAPDSSVFILHQCAHNPTGVDPSQ 201
Query: 193 DQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGL 252
+QW IA + + + FFDSAYQG+ASGSLD DAYA R FA+RG+E+LLAQSFSKNMGL
Sbjct: 202 EQWDEIASLMLAKHHQVFFDSAYQGYASGSLDTDAYAARLFARRGIEVLLAQSFSKNMGL 261
Query: 253 YAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQE 312
Y+ER G +S ++ D +++ V+S ++ + R Y+ PP HGAR+AHL++S+ LR EWE E
Sbjct: 262 YSERAGTLSLLLKDKTKRADVKSVMDSLIREEYTCPPAHGARLAHLILSNNALRKEWEAE 321
Query: 313 LKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLP 372
L M R+R+MR+ VY+ L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+
Sbjct: 322 LSSMAERIRTMRRTVYDELLRLQTPGSWEHVINQTGMFSFLGLSKAQCEYCQNHNIFITS 381
Query: 373 VGRANLAALTPSTMDFLVKSIDDVVRHV 400
GRAN+A LT T L ++I+D VR+V
Sbjct: 382 SGRANMAGLTHETALMLAQTINDAVRNV 409
>gi|109450660|emb|CAJ40952.1| aspartate aminotransferase [Leishmania donovani]
Length = 369
Score = 400 bits (1027), Expect = e-109, Method: Composition-based stats.
Identities = 186/355 (52%), Positives = 246/355 (69%), Gaps = 1/355 (0%)
Query: 32 DLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGLLNFVEEAVKLAYGNTVPL 91
+LVIGAYRD+ G PYPL+VVRKAER ++DM LD EY P++G F++EAVK+ YG+TV L
Sbjct: 12 NLVIGAYRDEQGRPYPLRVVRKAERLLLDMNLDYEYLPISGYQPFIDEAVKMIYGDTVAL 71
Query: 92 ERIXXXXXXXXXXXXXXXXXXXRQVV-PEDTPVYVSNPTWSNHVSIFGIVGHKNIREYRY 150
E + +V E TP+Y+S+PTW NH I G KNI Y Y
Sbjct: 72 ENLVAVQTLSGTGAVSLGAKLLTRVFDAEKTPIYLSDPTWPNHYGIVKAAGWKNICTYAY 131
Query: 151 YSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSKDQWATIADVFVERKLIPF 210
Y P T LDF G+ +D+ AP GS+ +LH CAHNPTGVDPS++QW IA + + ++ F
Sbjct: 132 YDPKTVSLDFEGMKKDILAAPDGSVFILHQCAHNPTGVDPSQEQWDEIASLMLAKRHQVF 191
Query: 211 FDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGLYAERVGVISAVVSDASRK 270
FDSAYQG+ASGSLD DAYA R FA RG+ +LLAQSFSKNMGLY+ER G +S ++ D +++
Sbjct: 192 FDSAYQGYASGSLDTDAYAARLFAHRGIXVLLAQSFSKNMGLYSERAGTLSLLLKDKTKR 251
Query: 271 EAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQELKEMVNRVRSMRQGVYEG 330
V+S ++ + R Y+ PP HGAR+AHL++S+ ELR EWE EL M R+R+MR+ VY+
Sbjct: 252 TDVKSXMDSLIRXEYTCPPAHGARLAHLILSNNELRKEWEAELSAMAERIRTMRRTVYDE 311
Query: 331 LMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEKRVFVLPVGRANLAALTPST 385
L++L TPG+WEH+INQ GMFS++GLS+ QCE +F+ GRAN+A LT T
Sbjct: 312 LLRLQTPGSWEHVINQIGMFSFLGLSKAQCEYCQNHNIFITLSGRANMAGLTHET 366
>gi|156364446|ref|XP_001626359.1| predicted protein [Nematostella vectensis]
gi|156213232|gb|EDO34259.1| predicted protein [Nematostella vectensis]
Length = 413
Score = 345 bits (885), Expect = 3e-93, Method: Composition-based stats.
Identities = 177/404 (43%), Positives = 240/404 (59%), Gaps = 10/404 (2%)
Query: 5 FKDLAPVPLDPVFGLXX-XXXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERR----IV 59
FKD+ VP D VF + +L +GAYRD +G P+ L VV K E + I
Sbjct: 7 FKDVPLVPTDHVFHVMACYNKDKDPSKINLGVGAYRDNDGKPWVLPVVSKVETQLAQGIA 66
Query: 60 DMGLDKEYPPMTGLLNFVEEAVKLAYGNTVPL---ERIXXXXXXXXXXXXXXXXXXXRQV 116
D L+ EY + GL F + A KL G P R+ Q
Sbjct: 67 DGTLNHEYLGIDGLRQFSDAACKLLLGGDHPAIAQNRVCGIQSISGTGSVFLGLKFLYQF 126
Query: 117 VPEDTPVYVSNPTWSNHVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSII 176
T Y+S PTW NH+ VG +IREYRYY T +DF + EDL AP+GSII
Sbjct: 127 YNCKT-AYISKPTWGNHLKTLKAVGFTDIREYRYYKAETCSVDFDAMWEDLEKAPEGSII 185
Query: 177 VLHACAHNPTGVDPSKDQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKR 236
VLH CAHNPTGVD S DQW IAD+ +R+L P+FD+AYQGFASG +DEDA+A+R+FA +
Sbjct: 186 VLHECAHNPTGVDLSHDQWIKIADIMKKRQLFPYFDTAYQGFASGDVDEDAWAVRYFASQ 245
Query: 237 GMEMLLAQSFSKNMGLYAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIA 296
G E++ AQSF+KN GLY ER G + V SD E +RS+++ + R +S PP HGARI
Sbjct: 246 GFELIAAQSFAKNFGLYNERAGNVCVVTSDDDCAERIRSQMKALIRPMWSNPPNHGARIV 305
Query: 297 HLVMSDKELRAEWEQELKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLS 356
++ + L+AEW + + M R+ MRQ ++ L +LGTPGTW H+I+Q+GMFS+ GL+
Sbjct: 306 ATILCNDTLQAEWRECVHTMGQRMLQMRQALFSKLKELGTPGTWNHVIDQRGMFSFTGLN 365
Query: 357 RPQCERLCEK-RVFVLPVGRANLAALTPSTMDFLVKSIDDVVRH 399
Q RL EK +++L GR N+ LTP+ ++++ ++I DVV H
Sbjct: 366 LKQVRRLTEKHHIYLLDSGRINICGLTPANVEYVARAIHDVVTH 409
>gi|68302096|gb|AAY89413.1| aspartate aminotransferase [Onchocerca volvulus]
gi|68302098|gb|AAY89414.1| aspartate aminotransferase [Onchocerca volvulus]
Length = 404
Score = 337 bits (865), Expect = 7e-91, Method: Composition-based stats.
Identities = 159/373 (42%), Positives = 235/373 (63%), Gaps = 4/373 (1%)
Query: 32 DLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPMTGLLNFVEEAVKLAYGNTVPL 91
+L +GAYR Q G P+ L VVR+AE+R+ D +D EY P+ G F AV+L G P+
Sbjct: 33 NLTVGAYRTQEGKPWVLPVVREAEKRLAD-SMDHEYLPVLGYEPFCNAAVELLLGKDSPI 91
Query: 92 ERIXXXXXXXXXXXXXXXXXXXR--QVVPEDTPVYVSNPTWSNHVSIFGIVGHKNIREYR 149
+ V + VY+S P+WSNH +F G K+IREY
Sbjct: 92 IKAGKATGVQCLSGTGSLKAGADFLSFVLKMKTVYISKPSWSNHELVFARAGFKDIREYY 151
Query: 150 YYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTGVDPSKDQWATIADVFVERKLIP 209
Y+ + ++ ++ DL AP+ S+++LH CAHNPTG+DP+ DQW IA++F +R L P
Sbjct: 152 YWDATNRCINMKSMLADLEAAPENSVVILHGCAHNPTGMDPTHDQWKQIAEIFKKRHLFP 211
Query: 210 FFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFSKNMGLYAERVGVISAVVSDASR 269
FFD AYQGFASG +D DA+A+R+F ++G+E+ AQSF+KN GLY ERVG ++ VVSD SR
Sbjct: 212 FFDLAYQGFASGDVDADAWAVRYFVEQGLELFCAQSFAKNFGLYNERVGNLTVVVSDPSR 271
Query: 270 KEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRAEWEQELKEMVNRVRSMRQGVYE 329
+ +S++ +I RS +S PP HGA+I H++++ + A+W +K M +R++SMRQ + E
Sbjct: 272 LTSFKSQMSLIIRSNWSNPPNHGAKIVHMILTSPSMCAQWHDAIKMMSSRIKSMRQALRE 331
Query: 330 GLMKLGTPGTWEHIINQKGMFSYMGLSRPQCERLC-EKRVFVLPVGRANLAALTPSTMDF 388
L K GTPG WEHI Q GMFS+ GL+ Q + L E +VF+L GR N+ L +++
Sbjct: 332 NLEKFGTPGKWEHITQQIGMFSFTGLNAEQVDHLVKEYKVFLLKDGRINVCGLNSENVEY 391
Query: 389 LVKSIDDVVRHVR 401
+ K+I + +++V+
Sbjct: 392 VAKAISETIKNVK 404
>gi|170085195|ref|XP_001873821.1| glutamic oxaloacetic transaminase AAT1 [Laccaria bicolor S238N-H82]
gi|164651373|gb|EDR15613.1| glutamic oxaloacetic transaminase AAT1 [Laccaria bicolor S238N-H82]
Length = 422
Score = 334 bits (856), Expect = 7e-90, Method: Composition-based stats.
Identities = 175/393 (44%), Positives = 239/393 (60%), Gaps = 7/393 (1%)
Query: 12 PLDPVFGLXXXXXXXXX-XXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGLDKEYPPM 70
P DP+ G+ +L +GAYRD++G PY L V++AE R+ + DKEY P+
Sbjct: 28 PPDPILGVTEAYKADKDPRKINLGVGAYRDEHGKPYVLPSVKEAEARLSALKPDKEYLPI 87
Query: 71 TGLLNFVEEAVKLAYG-NTVPLER--IXXXXXXXXXXXXXXXXXXXRQVVPEDTPVYVSN 127
TGL F + A LAYG ++ PL++ I + P +Y+
Sbjct: 88 TGLAEFTQNAALLAYGADSEPLKQGSISVTQSISGTGALRIGGAFLARHYPNSKIIYLPV 147
Query: 128 PTWSNHVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHACAHNPTG 187
P+W NH IF G + +R YRY+ T LDF GL DL AP+ SI++LHACAHNPTG
Sbjct: 148 PSWGNHTPIFRDSGLE-VRGYRYFDKKTVGLDFEGLKADLLAAPEQSIVLLHACAHNPTG 206
Query: 188 VDPSKDQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEMLLAQSFS 247
VDP+++QWA I+D+ ERKL PFFD AYQGFASGS DA+A+RHF G + LAQSF+
Sbjct: 207 VDPTQEQWAQISDIVKERKLFPFFDMAYQGFASGSTSHDAFAVRHFVSEGHHIALAQSFA 266
Query: 248 KNMGLYAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMSDKELRA 307
KNMGLY ERVG S +D K V S+L+++ R YS PP+HGARIA+ ++ DK L
Sbjct: 267 KNMGLYGERVGAFSLTTTDPDEKARVNSQLKIVIRPTYSNPPLHGARIANKILGDKALYT 326
Query: 308 EWEQELKEMVNRVRSMRQGVYEGLM-KLGTPGTWEHIINQKGMFSYMGLSRPQCERLCEK 366
+WE E+K M +R+ SMR+ +Y L L TPG W HI +Q GMFS+ GL+ PQ + L EK
Sbjct: 327 QWESEVKGMADRIISMREKLYSALTHDLKTPGEWGHIKSQIGMFSFTGLTPPQTKALAEK 386
Query: 367 -RVFVLPVGRANLAALTPSTMDFLVKSIDDVVR 398
V++ GR ++A L +++ +S+D V+
Sbjct: 387 AHVYMTADGRISMAGLNGGNIEYFAESVDAAVK 419
>gi|66811806|ref|XP_640082.1| aspartate aminotransferase [Dictyostelium discoideum AX4]
gi|60468096|gb|EAL66106.1| aspartate aminotransferase [Dictyostelium discoideum AX4]
Length = 438
Score = 331 bits (848), Expect = 6e-89, Method: Composition-based stats.
Identities = 172/397 (43%), Positives = 236/397 (59%), Gaps = 7/397 (1%)
Query: 5 FKDLAPVPLDPVFGLXXX-XXXXXXXXXDLVIGAYRDQNGLPYPLKVVRKAERRIVDMGL 63
F ++ P+DP+ G+ D +GAYRD+NG PY LK V +AE+R+ +G
Sbjct: 41 FANVPLGPVDPILGVSTAFKADTDPRKVDTSVGAYRDENGKPYVLKCVFEAEKRL--LGA 98
Query: 64 DKEYPPMTGLLNFVEEAVKLAYGNTV--PLERIXXXXXXXXXXXXXXXXXXXRQVVPEDT 121
KEY P+ G+ F + + KL YG+ + +R+ R+ +P T
Sbjct: 99 PKEYLPIDGIPEFNKLSAKLLYGDAMVGKEKRMVTVQALSGTGALRIGIIFIRKYLPAGT 158
Query: 122 PVYVSNPTWSNHVSIFGIVGHKNIREYRYYSPSTHELDFVGLIEDLNVAPQGSIIVLHAC 181
VY+S P+W+NH +I G ++ EY YY P T LDF G+I D+ AP GS+ VLH C
Sbjct: 159 VVYISRPSWTNHHNICKESGVQSA-EYAYYDPKTKGLDFTGMINDMRAAPNGSVFVLHLC 217
Query: 182 AHNPTGVDPSKDQWATIADVFVERKLIPFFDSAYQGFASGSLDEDAYAIRHFAKRGMEML 241
AHNPTGVDP+ +QW IADV E+ IPF D AYQG+ASG LD DAY+ R F RG EM
Sbjct: 218 AHNPTGVDPTHEQWNIIADVMREKNHIPFMDCAYQGYASGDLDYDAYSARLFLNRGFEMF 277
Query: 242 LAQSFSKNMGLYAERVGVISAVVSDASRKEAVRSRLEVIARSYYSTPPVHGARIAHLVMS 301
AQS+SKN GLY ER G ++ V + S+L++ R+ YS+PP HGAR+ V+S
Sbjct: 278 SAQSYSKNFGLYGERTGALTIVSHREDVIPKMLSQLKMDIRAMYSSPPTHGARLVTTVLS 337
Query: 302 DKELRAEWEQELKEMVNRVRSMRQGVYEGLMKLGTPGTWEHIINQKGMFSYMGLSRPQCE 361
D EL A W +ELKEM R++ +RQ V + L+ PG WEHI+NQ GMF+Y GL++PQ +
Sbjct: 338 DPELTALWVKELKEMSGRIKDVRQKVLDALIARKVPGNWEHIVNQIGMFTYTGLTKPQVD 397
Query: 362 RLCEK-RVFVLPVGRANLAALTPSTMDFLVKSIDDVV 397
L K +++L GR +LA L +D+ +I D V
Sbjct: 398 ILVNKYHIYLLGSGRVSLAGLNNKNIDYFADAILDAV 434