BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= XP_825010.1__[Trypanosoma_brucei]
         (458 letters)

Database: nr.pal 
           6,348,806 sequences; 2,166,943,470 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|72389512|ref|XP_845051.1|  orotidine-5-phosphate decarbox...   913   0.0  
gi|4210455|dbj|BAA74523.1|  OMPDCase-OPRTase [Trypanosoma cr...   716   0.0  
gi|71421013|ref|XP_811679.1|  orotidine-5-phosphate decarbox...   707   0.0  
gi|154334825|ref|XP_001563659.1|  OMPDCase-OPRTase, putative...   649   0.0  
gi|146082558|ref|XP_001464543.1|  OMPDCase-OPRTase, putative...   636   0.0  
gi|157867157|ref|XP_001682133.1|  OMPDCase-OPRTase, putative...   621   e-176
gi|7544112|dbj|BAA94297.1|  Orotidine 5'phosphate decarboxyl...   620   e-176
gi|71421770|ref|XP_811898.1|  orotidine-5-phosphate decarbox...   571   e-161
gi|58257617|dbj|BAD88795.1|  orotidine-5'-monophosphate deca...   560   e-158
gi|71405137|ref|XP_805212.1|  orotidine-5-phosphate decarbox...   411   e-113
gi|75907180|ref|YP_321476.1|  bifunctional orotidine 5'-phos...   313   1e-83
gi|17230437|ref|NP_486985.1|  bifunctional orotidine 5'-phos...   310   2e-82
gi|21362811|sp|Q8YSY4|PYRFE_ANASP  Bifunctional enzyme pyrF/...   309   3e-82
gi|23126878|ref|ZP_00108761.1|  COG0284: Orotidine-5'-phosph...   305   4e-81
gi|119511686|ref|ZP_01630791.1|  bifunctional orotidine 5'-p...   299   2e-79
gi|67924048|ref|ZP_00517498.1|  Orotate phosphoribosyl trans...   297   1e-78
gi|126660262|ref|ZP_01731377.1|  bifunctional orotidine 5'-p...   295   6e-78
gi|119493601|ref|ZP_01624265.1|  hypothetical protein L8106_...   273   2e-71
gi|37520648|ref|NP_924025.1|  bifunctional orotidine 5'-phos...   266   2e-69
gi|113474256|ref|YP_720317.1|  bifunctional orotidine 5'-pho...   260   2e-67
gi|113952716|ref|YP_729596.1|  bifunctional orotidine 5'-pho...   251   7e-65
gi|87302588|ref|ZP_01085405.1|  bifunctional orotidine 5'-ph...   249   2e-64
gi|88807296|ref|ZP_01122808.1|  bifunctional orotidine 5'-ph...   246   2e-63
gi|116075686|ref|ZP_01472945.1|  bifunctional orotidine 5'-p...   243   3e-62
gi|148654371|ref|YP_001274576.1|  orotidine 5'-phosphate dec...   223   2e-56
gi|156744262|ref|YP_001434391.1|  orotidine 5'-phosphate dec...   217   1e-54
gi|17547492|ref|NP_520894.1|  orotidine 5'-phosphate decarbo...   216   4e-54
gi|20139406|sp|P58642|PYRF_RALSO  Orotidine 5'-phosphate dec...   215   6e-54
gi|73542536|ref|YP_297056.1|  orotidine 5'-phosphate decarbo...   213   3e-53
gi|121527923|ref|ZP_01660537.1|  putative orotidine 5'-phosp...   212   6e-53
gi|94311981|ref|YP_585191.1|  orotidine 5'-phosphate decarbo...   212   6e-53
gi|118033488|ref|ZP_01504931.1|  orotidine 5'-phosphate deca...   212   6e-53
gi|159897969|ref|YP_001544216.1|  orotidine 5'-phosphate dec...   212   6e-53
gi|78065184|ref|YP_367953.1|  orotidine 5'-phosphate decarbo...   211   8e-53
gi|107021703|ref|YP_620030.1|  orotidine 5'-phosphate decarb...   210   1e-52
gi|113869111|ref|YP_727600.1|  orotidine 5'-phosphate decarb...   210   2e-52
gi|115350581|ref|YP_772420.1|  orotidine 5'-phosphate decarb...   210   2e-52
gi|134294713|ref|YP_001118448.1|  orotidine 5'-phosphate dec...   209   3e-52
gi|91785227|ref|YP_560433.1|  orotidine 5'-phosphate decarbo...   209   3e-52
gi|170731947|ref|YP_001763894.1|  orotidine 5'-phosphate dec...   208   5e-52
gi|118044584|ref|ZP_01513292.1|  orotidine 5'-phosphate deca...   208   5e-52
gi|161525928|ref|YP_001580940.1|  orotidine 5'-phosphate dec...   207   1e-51
gi|91790445|ref|YP_551397.1|  orotidine 5'-phosphate decarbo...   205   5e-51
gi|71909062|ref|YP_286649.1|  orotidine 5'-phosphate decarbo...   205   5e-51
gi|84360743|ref|ZP_00985436.1|  COG0284: Orotidine-5'-phosph...   201   8e-50
gi|119899948|ref|YP_935161.1|  orotidine 5'-phosphate decarb...   200   2e-49
gi|57233658|ref|YP_180768.1|  orotidine 5'-phosphate decarbo...   200   2e-49
gi|83721020|ref|YP_441731.1|  orotidine 5'-phosphate decarbo...   200   2e-49
gi|121596342|ref|YP_988238.1|  orotidine 5'-phosphate decarb...   200   2e-49
gi|53720571|ref|YP_109557.1|  orotidine 5'-phosphate decarbo...   199   5e-49
gi|73747968|ref|YP_307207.1|  orotidine 5'-phosphate decarbo...   198   6e-49
gi|147668664|ref|YP_001213482.1|  orotidine 5'-phosphate dec...   198   7e-49
gi|84356741|ref|ZP_00981577.1|  COG0284: Orotidine-5'-phosph...   197   1e-48
gi|121606731|ref|YP_984060.1|  orotidine 5'-phosphate decarb...   197   2e-48
gi|134093889|ref|YP_001098964.1|  orotidine 5'-phosphate dec...   195   8e-48
gi|120613327|ref|YP_973005.1|  orotidine 5'-phosphate decarb...   193   2e-47
gi|55378292|ref|YP_136142.1|  orotidine 5'-phosphate decarbo...   192   3e-47
gi|89902536|ref|YP_525007.1|  orotidine 5'-phosphate decarbo...   191   7e-47
gi|118051676|ref|ZP_01520224.1|  orotidine 5'-phosphate deca...   189   3e-46
gi|56476702|ref|YP_158291.1|  orotidine 5'-phosphate decarbo...   188   6e-46
gi|124003581|ref|ZP_01688430.1|  orotidine 5'-phosphate deca...   188   7e-46
gi|78187990|ref|YP_378328.1|  Orotidine 5'-phosphate decarbo...   188   8e-46
gi|33594365|ref|NP_882009.1|  orotidine 5'-phosphate decarbo...   188   8e-46
gi|148767808|gb|ABR10851.1|  orotidine 5'-phosphate decarbox...   187   1e-45
gi|148767814|gb|ABR10854.1|  orotidine 5'-phosphate decarbox...   187   2e-45
gi|148767840|gb|ABR10867.1|  orotidine 5'-phosphate decarbox...   187   2e-45
gi|146300077|ref|YP_001194668.1|  orotidine 5'-phosphate dec...   187   2e-45
gi|148767842|gb|ABR10868.1|  orotidine 5'-phosphate decarbox...   187   2e-45
gi|126646409|ref|ZP_01718926.1|  orotidine 5'-phosphate deca...   187   2e-45
gi|148767832|gb|ABR10863.1|  orotidine 5'-phosphate decarbox...   186   2e-45
gi|148767836|gb|ABR10865.1|  orotidine 5'-phosphate decarbox...   186   3e-45
gi|148767798|gb|ABR10846.1|  orotidine 5'-phosphate decarbox...   186   3e-45
gi|148767834|gb|ABR10864.1|  orotidine 5'-phosphate decarbox...   186   3e-45
gi|148767800|gb|ABR10847.1|  orotidine 5'-phosphate decarbox...   186   3e-45
gi|148767806|gb|ABR10850.1|  orotidine 5'-phosphate decarbox...   186   4e-45
gi|148767816|gb|ABR10855.1|  orotidine 5'-phosphate decarbox...   185   6e-45
gi|148767830|gb|ABR10862.1|  orotidine 5'-phosphate decarbox...   184   9e-45
gi|124268809|ref|YP_001022813.1|  orotidine 5'-phosphate dec...   184   9e-45
gi|83746782|ref|ZP_00943830.1|  Orotidine 5'-phosphate decar...   184   9e-45
gi|110639082|ref|YP_679291.1|  orotidine 5' phosphate decarb...   183   2e-44
gi|148767824|gb|ABR10859.1|  orotidine 5'-phosphate decarbox...   183   2e-44
gi|123514402|sp|Q2KY06|PYRF_BORA1  Orotidine 5'-phosphate de...   183   2e-44
gi|126663552|ref|ZP_01734549.1|  orotidine 5'-phosphate deca...   183   3e-44
gi|110669102|ref|YP_658913.1|  orotidine-5'-phosphate decarb...   182   5e-44
gi|110598265|ref|ZP_01386540.1|  Orotidine 5'-phosphate deca...   180   2e-43
gi|91217383|ref|ZP_01254343.1|  orotidine 5'-phosphate decar...   179   3e-43
gi|120434842|ref|YP_860528.1|  orotidine 5'-phosphate decarb...   179   4e-43
gi|145588407|ref|YP_001155004.1|  orotidine 5'-phosphate dec...   179   4e-43
gi|15790619|ref|NP_280443.1|  PyrF [Halobacterium sp. NRC-1]...   179   5e-43
gi|149369845|ref|ZP_01889696.1|  orotidine 5'-phosphate deca...   177   1e-42
gi|89890299|ref|ZP_01201809.1|  orotidine 5'-phosphate decar...   177   1e-42
gi|119358441|ref|YP_913085.1|  orotidine 5'-phosphate decarb...   176   3e-42
gi|21672970|ref|NP_661035.1|  orotidine 5'-phosphate decarbo...   176   4e-42
gi|88803808|ref|ZP_01119331.1|  orotidine 5'-phosphate decar...   175   6e-42
gi|60680382|ref|YP_210526.1|  putative orotidine 5'-phosphat...   175   8e-42
gi|53712202|ref|YP_098194.1|  orotidine 5'-phosphate decarbo...   175   8e-42
gi|86140560|ref|ZP_01059119.1|  orotidine 5'-phosphate decar...   174   1e-41
gi|83816641|ref|YP_445852.1|  orotidine 5'-phosphate decarbo...   174   2e-41
gi|67939744|ref|ZP_00532234.1|  Orotidine 5'-phosphate decar...   174   2e-41
gi|24217371|ref|NP_714854.1|  orotidine-5'-monophosphate dec...   173   2e-41
>gi|72389512|ref|XP_845051.1| orotidine-5-phosphate decarboxylase/orotate
           phosphoribosyltransferase, putative [Trypanosoma brucei
           TREU927]
 gi|62176734|gb|AAX70834.1| orotidine-5-phosphate decarboxylase/orotate
           phosphoribosyltransferase, putative [Trypanosoma brucei]
 gi|70801585|gb|AAZ11492.1| orotidine-5-phosphate decarboxylase/orotate
           phosphoribosyltransferase, putative [Trypanosoma brucei]
          Length = 458

 Score =  913 bits (2360), Expect = 0.0,   Method: Composition-based stats.
 Identities = 458/458 (100%), Positives = 458/458 (100%)

Query: 1   MSSTFFDMLNKRAKTTLLCIGLDPRADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECF 60
           MSSTFFDMLNKRAKTTLLCIGLDPRADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECF
Sbjct: 1   MSSTFFDMLNKRAKTTLLCIGLDPRADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECF 60

Query: 61  GAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDS 120
           GAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDS
Sbjct: 61  GAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDS 120

Query: 121 LQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVVGA 180
           LQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVVGA
Sbjct: 121 LQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVVGA 180

Query: 181 TDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQAKDPR 240
           TDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQAKDPR
Sbjct: 181 TDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQAKDPR 240

Query: 241 AVAQKLCEDINRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPL 300
           AVAQKLCEDINRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPL
Sbjct: 241 AVAQKLCEDINRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPL 300

Query: 301 IMRLVARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIE 360
           IMRLVARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIE
Sbjct: 301 IMRLVARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIE 360

Query: 361 GDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEF 420
           GDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEF
Sbjct: 361 GDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEF 420

Query: 421 HAVATLSQLLPLWLQQGAITDKQMREVTAFMLESTSKL 458
           HAVATLSQLLPLWLQQGAITDKQMREVTAFMLESTSKL
Sbjct: 421 HAVATLSQLLPLWLQQGAITDKQMREVTAFMLESTSKL 458
>gi|4210455|dbj|BAA74523.1| OMPDCase-OPRTase [Trypanosoma cruzi]
 gi|4995976|dbj|BAA31359.2| OMPDCase-OPRTase [Trypanosoma cruzi]
          Length = 458

 Score =  716 bits (1849), Expect = 0.0,   Method: Composition-based stats.
 Identities = 350/458 (76%), Positives = 397/458 (86%)

Query: 1   MSSTFFDMLNKRAKTTLLCIGLDPRADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECF 60
           M   FFDMLN+RAK+TLLCIGLD RA TAA A  EC R+ID T+ YAAAYKPNAAFFE F
Sbjct: 1   MPMAFFDMLNERAKSTLLCIGLDSRAKTAAEAKKECMRLIDATAEYAAAYKPNAAFFEFF 60

Query: 61  GAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDS 120
           G  GW AL++VIAH+P +IPV+LDAKRGDIADTAEAYAKSAF+ LK HAIT SPYMGGDS
Sbjct: 61  GGEGWKALQQVIAHVPANIPVVLDAKRGDIADTAEAYAKSAFEHLKAHAITTSPYMGGDS 120

Query: 121 LQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVVGA 180
           L PFL+Y+SKGVFVLCKTSNKGS+E+QCL+ NG+ LYE++AE AE VWNYN+NVGLVVGA
Sbjct: 121 LSPFLQYTSKGVFVLCKTSNKGSNEIQCLRVNGRRLYESVAEHAETVWNYNKNVGLVVGA 180

Query: 181 TDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQAKDPR 240
           TDP+ALSR R  APTLW LVPG+GAQGGDLKAAL AGLR DGSGLLINVSRAV +AKDPR
Sbjct: 181 TDPIALSRVRVRAPTLWFLVPGIGAQGGDLKAALNAGLRADGSGLLINVSRAVARAKDPR 240

Query: 241 AVAQKLCEDINRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPL 300
           A A+KLCEDIN +R      +++A ALVAS+CVRFG FTLKSGK SPIY+DLRRLVTHP 
Sbjct: 241 AAAKKLCEDINLVRFGKACSTDLAAALVASRCVRFGNFTLKSGKNSPIYLDLRRLVTHPS 300

Query: 301 IMRLVARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIE 360
           I+R+VAR YA +L T+QFDR+VGLPYAALPIATAISLEMN+PL+YPRRE K YGTK  IE
Sbjct: 301 ILRVVAREYANVLRTLQFDRLVGLPYAALPIATAISLEMNIPLVYPRREAKSYGTKAAIE 360

Query: 361 GDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEF 420
           GD++KGDRVV++DD+VTTG TK+EAIEKLKAAGL IVSIVVLIDREMGAKKFLGSLGYE 
Sbjct: 361 GDYKKGDRVVVIDDIVTTGGTKLEAIEKLKAAGLEIVSIVVLIDREMGAKKFLGSLGYEL 420

Query: 421 HAVATLSQLLPLWLQQGAITDKQMREVTAFMLESTSKL 458
            AV TLSQLLPLW Q GAIT +QM++V +FM  S+SKL
Sbjct: 421 EAVVTLSQLLPLWRQAGAITQQQMKDVHSFMAGSSSKL 458
>gi|71421013|ref|XP_811679.1| orotidine-5-phosphate decarboxylase/orotate
           phosphoribosyltransferase, putative [Trypanosoma cruzi
           strain CL Brener]
 gi|70876367|gb|EAN89828.1| orotidine-5-phosphate decarboxylase/orotate
           phosphoribosyltransferase, putative [Trypanosoma cruzi]
          Length = 458

 Score =  707 bits (1826), Expect = 0.0,   Method: Composition-based stats.
 Identities = 348/458 (75%), Positives = 396/458 (86%)

Query: 1   MSSTFFDMLNKRAKTTLLCIGLDPRADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECF 60
           M   FFDMLN+RAK+TLLCIGLDPRA TAA A  EC R+ID T+ YAAAYKPNAAFFE F
Sbjct: 1   MPMAFFDMLNERAKSTLLCIGLDPRAKTAAEAAKECIRLIDATAEYAAAYKPNAAFFEFF 60

Query: 61  GAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDS 120
           G  GW AL++VIAH+P +IPV+LDAKRGDIADTAEAYAKSAF+ LK HAIT SPYMGGDS
Sbjct: 61  GEEGWKALQQVIAHVPANIPVVLDAKRGDIADTAEAYAKSAFEHLKAHAITTSPYMGGDS 120

Query: 121 LQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVVGA 180
           L PFL+Y+SKGVFVLCKTSNKGS+E+QCL+ NG+ LYE++AE AE VWNYN+NVGLVVGA
Sbjct: 121 LSPFLQYASKGVFVLCKTSNKGSNEIQCLRVNGRHLYESVAEHAETVWNYNKNVGLVVGA 180

Query: 181 TDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQAKDPR 240
           TDP+ALSR R  APTLW LVPG+GAQGGDLK AL AGLR DGSGLLINVSRAV +AKDPR
Sbjct: 181 TDPIALSRVRVRAPTLWFLVPGIGAQGGDLKEALNAGLRADGSGLLINVSRAVARAKDPR 240

Query: 241 AVAQKLCEDINRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPL 300
           A A+K CEDIN +R      +++A ALVAS+CVRFG FTLKSGK SPIY+DLRRLVTHP 
Sbjct: 241 AAAKKFCEDINLVRFGKACSTDLAAALVASRCVRFGNFTLKSGKNSPIYLDLRRLVTHPS 300

Query: 301 IMRLVARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIE 360
           I+RLVAR YA +L T+QFDR+VGLPYAALPIATAISLEMN+PL+YPRRE K YGTK  IE
Sbjct: 301 ILRLVAREYANVLRTLQFDRLVGLPYAALPIATAISLEMNIPLVYPRREAKSYGTKAAIE 360

Query: 361 GDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEF 420
           GD++KGDRVV++DD+VTTG TK+EAIEKLKAAGL IVSIVVLIDREMGAK+ LGSLGYE 
Sbjct: 361 GDYKKGDRVVVIDDIVTTGGTKLEAIEKLKAAGLEIVSIVVLIDREMGAKQLLGSLGYEL 420

Query: 421 HAVATLSQLLPLWLQQGAITDKQMREVTAFMLESTSKL 458
            AV TLSQLLPLW Q GAIT +QM++V +FM E++SKL
Sbjct: 421 EAVVTLSQLLPLWRQAGAITQQQMKDVQSFMAEASSKL 458
>gi|154334825|ref|XP_001563659.1| OMPDCase-OPRTase, putative [Leishmania braziliensis
           MHOM/BR/75/M2904]
 gi|134060681|emb|CAM37696.1| OMPDCase-OPRTase, putative; orotidine-5-phosphate
           decarboxylase/orotate phosphoribosyltransferase,
           putative [Leishmania braziliensis]
          Length = 457

 Score =  649 bits (1673), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/448 (71%), Positives = 369/448 (82%)

Query: 4   TFFDMLNKRAKTTLLCIGLDPRADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECFGAA 63
           +FFD+LN+RAK +LLC+GLDPRA TAAAAV ECK +I+ T  YAAAYKPNAAFFE FGA 
Sbjct: 2   SFFDLLNERAKHSLLCVGLDPRAKTAAAAVRECKHLIEQTHEYAAAYKPNAAFFEFFGAE 61

Query: 64  GWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDSLQP 123
           GW+AL EVI  IP  IPV+LDAKRGDIADTA+AYA SAF+ LK HAITASPYMG DSLQ 
Sbjct: 62  GWAALSEVIRAIPAGIPVVLDAKRGDIADTADAYATSAFKHLKAHAITASPYMGADSLQS 121

Query: 124 FLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVVGATDP 183
           FL+Y+ KGVFVLCKTSNKGS++LQCL+   + LYE +AERAE +WN NRNVGLVVGATDP
Sbjct: 122 FLRYADKGVFVLCKTSNKGSNDLQCLRVGDRYLYEAVAERAEGLWNANRNVGLVVGATDP 181

Query: 184 VALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQAKDPRAVA 243
           +AL+R RA APTLW LVPG+GAQGG L+A+L AGLR DGSG+LINVSR +  A DPRA A
Sbjct: 182 IALARVRARAPTLWFLVPGIGAQGGSLRASLDAGLRADGSGMLINVSRGLASATDPRAAA 241

Query: 244 QKLCEDINRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMR 303
           ++LCE IN IR       E+A ALV S CVRFG F LKSGK+SPIYIDLR LVT+P IMR
Sbjct: 242 KELCEAINVIRFAKGASVELAKALVDSHCVRFGNFMLKSGKSSPIYIDLRLLVTYPTIMR 301

Query: 304 LVARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDF 363
           LVAR YA++L   +FDRI GLPYAALPIA+AIS EMNVPLIYPRRE K YGTK  IEG++
Sbjct: 302 LVAREYAKVLRHYKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKSYGTKASIEGEY 361

Query: 364 QKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEFHAV 423
           +KGDRVVI+DDLV+TGETKVEAIEKLK+AGL +VSIVVL+DREMGAK FL  LGY+F AV
Sbjct: 362 KKGDRVVIIDDLVSTGETKVEAIEKLKSAGLEVVSIVVLVDREMGAKAFLNKLGYDFEAV 421

Query: 424 ATLSQLLPLWLQQGAITDKQMREVTAFM 451
             L QLLPLW Q  A+T +Q  +V AF+
Sbjct: 422 VGLYQLLPLWRQSNAMTSQQEADVRAFL 449
>gi|146082558|ref|XP_001464543.1| OMPDCase-OPRTase, putative [Leishmania infantum JPCM5]
 gi|134068636|emb|CAM66934.1| OMPDCase-OPRTase, putative; orotidine-5-phosphate
           decarboxylase/orotate phosphoribosyltransferase,
           putative [Leishmania infantum]
          Length = 457

 Score =  636 bits (1641), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/448 (71%), Positives = 370/448 (82%)

Query: 4   TFFDMLNKRAKTTLLCIGLDPRADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECFGAA 63
           +FFD+LN+RAK +LLC+GLDPRA TAAAAV ECKR+I+ T  YAAAYKPNAAFFE FGA 
Sbjct: 2   SFFDLLNERAKRSLLCVGLDPRAKTAAAAVEECKRLIEQTHEYAAAYKPNAAFFEFFGAE 61

Query: 64  GWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDSLQP 123
           GW+AL EVI  +P  IPV+LDAKRGDIADTA+AYA SAF+ L  HAITASPYMG DSLQP
Sbjct: 62  GWAALSEVIRAVPAGIPVVLDAKRGDIADTADAYATSAFKHLNAHAITASPYMGSDSLQP 121

Query: 124 FLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVVGATDP 183
           F++Y  K VFVLCKTSNKGS++LQCL+   + LYE +AERAE  WN N NVGLVVGATDP
Sbjct: 122 FMRYPDKAVFVLCKTSNKGSNDLQCLRVGDRYLYEAVAERAEGPWNVNGNVGLVVGATDP 181

Query: 184 VALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQAKDPRAVA 243
           VAL+R RA APTLW LVPG+GAQGG LKA+L AGLR DGSG+LINVSR + +A DPRA A
Sbjct: 182 VALARVRARAPTLWFLVPGIGAQGGSLKASLDAGLRADGSGMLINVSRGLARAADPRAAA 241

Query: 244 QKLCEDINRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMR 303
           ++LCE+IN IR       E+A ALV S CVRFG FTLKSGK+SPIYIDLRRLVT+P IMR
Sbjct: 242 KELCEEINAIRFAKGASVELAKALVDSHCVRFGNFTLKSGKSSPIYIDLRRLVTYPAIMR 301

Query: 304 LVARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDF 363
           LVAR YA++L   +FDRI GLPYAALPIA+AIS EMNVPLIYPRRE K YGTK  IEG++
Sbjct: 302 LVAREYAKVLRHYKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKIYGTKAAIEGEY 361

Query: 364 QKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEFHAV 423
           +KGDRVVI+DDLV+TGETKVEAIEKL++AGL +VSIVVL+DR+MGAK FL  LGY+F AV
Sbjct: 362 KKGDRVVIIDDLVSTGETKVEAIEKLRSAGLEVVSIVVLVDRDMGAKAFLNKLGYDFEAV 421

Query: 424 ATLSQLLPLWLQQGAITDKQMREVTAFM 451
             L QLLPLW +  AIT +Q  +V AF+
Sbjct: 422 VGLHQLLPLWRKSNAITSQQEADVRAFL 449
>gi|157867157|ref|XP_001682133.1| OMPDCase-OPRTase, putative; orotidine-5-phosphate
           decarboxylase/orotate phosphoribosyltransferase,
           putative [Leishmania major]
 gi|68125585|emb|CAJ03559.1| OMPDCase-OPRTase, putative; orotidine-5-phosphate
           decarboxylase/orotate phosphoribosyltransferase,
           putative [Leishmania major]
          Length = 457

 Score =  621 bits (1602), Expect = e-176,   Method: Composition-based stats.
 Identities = 318/448 (70%), Positives = 365/448 (81%)

Query: 4   TFFDMLNKRAKTTLLCIGLDPRADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECFGAA 63
           +FFD+LN RAK +LLC+GLDPRA TA AA  ECKR+I+ T  YAAAYKPNAAFFE FGA 
Sbjct: 2   SFFDLLNARAKRSLLCVGLDPRAKTATAAAEECKRLIEQTHEYAAAYKPNAAFFEFFGAE 61

Query: 64  GWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDSLQP 123
           GW+AL EVI  +P  IPV+LDAKRGDIADTA+AYA SAF+ L  HAITASPYMG DSLQP
Sbjct: 62  GWAALSEVIRAVPAGIPVVLDAKRGDIADTADAYATSAFKHLNAHAITASPYMGSDSLQP 121

Query: 124 FLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVVGATDP 183
           F+ Y  K VFVLCKTSNKGS +LQCL+   + LYE +AERAE  WN N NVGLVVGATDP
Sbjct: 122 FMGYPDKAVFVLCKTSNKGSDDLQCLRVGDKYLYEAVAERAEGPWNVNGNVGLVVGATDP 181

Query: 184 VALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQAKDPRAVA 243
           VAL+R RA APTLW LVPG+GAQGG LKA+L AGLR DGSG+LINVSR + +A DPRA A
Sbjct: 182 VALARVRARAPTLWFLVPGIGAQGGSLKASLDAGLRADGSGMLINVSRGLARAADPRAAA 241

Query: 244 QKLCEDINRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMR 303
           ++LCE+IN IR       E+A ALV S CVRFG FTLKSGK+SPIYIDLRRLVT+P IMR
Sbjct: 242 KELCEEINAIRFAKGASVELAKALVDSHCVRFGNFTLKSGKSSPIYIDLRRLVTYPAIMR 301

Query: 304 LVARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDF 363
           LVAR YA++L   +FDRI GLPYAALPIA+AIS EMNVPLIYPRRE K YGTK  IEG++
Sbjct: 302 LVAREYAKVLRHYKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKIYGTKAAIEGEY 361

Query: 364 QKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEFHAV 423
           +KGDRVVI+DDLV+TGETKVEAIEKL++AGL +VSIVVL+DR+MGAK FL  LGY+F AV
Sbjct: 362 KKGDRVVIIDDLVSTGETKVEAIEKLRSAGLEVVSIVVLVDRDMGAKAFLSKLGYDFEAV 421

Query: 424 ATLSQLLPLWLQQGAITDKQMREVTAFM 451
             L QLLPLW +  AIT +Q  +V AF+
Sbjct: 422 VGLHQLLPLWRKSNAITSQQEADVRAFL 449
>gi|7544112|dbj|BAA94297.1| Orotidine 5'phosphate decarboxylase-Orotate
           phosphoribosyltransferase [Leishmania amazonensis]
          Length = 457

 Score =  620 bits (1598), Expect = e-176,   Method: Composition-based stats.
 Identities = 317/448 (70%), Positives = 367/448 (81%)

Query: 4   TFFDMLNKRAKTTLLCIGLDPRADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECFGAA 63
           +FFD+LN+RAK +LLC+GLDPRA+TAAAAV ECK +I+ T  YAAAYKPNAAFFE FGA 
Sbjct: 2   SFFDLLNERAKRSLLCVGLDPRAETAAAAVEECKCLIEQTHEYAAAYKPNAAFFELFGAE 61

Query: 64  GWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDSLQP 123
           GW+AL EVI  +P DIPV+LDAKRGDIADTA+AYA SAF+ L  HAITASPYMG DSLQP
Sbjct: 62  GWTALLEVIGAVPPDIPVVLDAKRGDIADTADAYATSAFKHLNAHAITASPYMGADSLQP 121

Query: 124 FLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVVGATDP 183
           F++Y  K VFVLCKTSNKGS + QCL+   + LYE +AERAE  WN N NVGLVVGATDP
Sbjct: 122 FMRYPEKAVFVLCKTSNKGSYDFQCLRVGDKYLYEAVAERAEGSWNVNGNVGLVVGATDP 181

Query: 184 VALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQAKDPRAVA 243
           VAL   RA APTLW LVPG+GAQGG LKA+L AGLR DGSG+LINVSR + +A DPRA A
Sbjct: 182 VALGCVRARAPTLWFLVPGIGAQGGSLKASLDAGLRADGSGMLINVSRGLARAADPRAAA 241

Query: 244 QKLCEDINRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMR 303
           ++LCE+IN +R       E+A ALV S CVRFG FTLKSGK+SPIYIDLRRLVT+P IMR
Sbjct: 242 KELCEEINSMRFAKGASVELAKALVDSHCVRFGNFTLKSGKSSPIYIDLRRLVTYPAIMR 301

Query: 304 LVARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDF 363
           LVAR YA++L   +FDRI GLPYAALPIA+AIS EMNVPLIYPRRE K YGTK  IEG++
Sbjct: 302 LVAREYAKVLRHYKFDRIAGLPYAALPIASAISNEMNVPLIYPRREAKVYGTKAAIEGEY 361

Query: 364 QKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEFHAV 423
           +KGDRVVI+DDLV+TGETKVEAIEKL++AGL +VSIVVL+DR+MGAK FL  LGY+F AV
Sbjct: 362 KKGDRVVIIDDLVSTGETKVEAIEKLRSAGLEVVSIVVLVDRDMGAKAFLNKLGYDFEAV 421

Query: 424 ATLSQLLPLWLQQGAITDKQMREVTAFM 451
             L QLLPLW +  AIT +Q  +V AF+
Sbjct: 422 VALHQLLPLWRKSNAITSQQEADVRAFL 449
>gi|71421770|ref|XP_811898.1| orotidine-5-phosphate decarboxylase/orotate
           phosphoribosyltransferase, putative [Trypanosoma cruzi
           strain CL Brener]
 gi|70876613|gb|EAN90047.1| orotidine-5-phosphate decarboxylase/orotate
           phosphoribosyltransferase, putative [Trypanosoma cruzi]
          Length = 363

 Score =  571 bits (1472), Expect = e-161,   Method: Composition-based stats.
 Identities = 278/363 (76%), Positives = 317/363 (87%)

Query: 96  AYAKSAFQRLKVHAITASPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQS 155
           AYAKSAF+ LK HAIT SPYMGGDSL PFL+Y+SKGVFVLCKTSNKGS+E+QCL+ NG+ 
Sbjct: 1   AYAKSAFEHLKAHAITTSPYMGGDSLSPFLQYASKGVFVLCKTSNKGSNEIQCLRVNGRH 60

Query: 156 LYETIAERAERVWNYNRNVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQ 215
           LYE++AE AE VWNYN+NVGLVVGATDP+ALSR R  APTLW LVPG+GAQGGDLK AL 
Sbjct: 61  LYESVAEHAETVWNYNKNVGLVVGATDPIALSRVRVRAPTLWFLVPGIGAQGGDLKEALN 120

Query: 216 AGLRTDGSGLLINVSRAVTQAKDPRAVAQKLCEDINRIRLRTNNVSEMAGALVASQCVRF 275
           AGLR DGSGLLINVSRAV +AKDPRA A+KLCEDIN +R      +++A ALVAS+CVRF
Sbjct: 121 AGLRADGSGLLINVSRAVARAKDPRAAAKKLCEDINLVRFGKACSTDLAAALVASRCVRF 180

Query: 276 GKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTTMQFDRIVGLPYAALPIATAI 335
           G FTLKSGK SPIY+DLRRLVTHP I+RLVAR YA +L T+QFDR+VGLPYAALPIATAI
Sbjct: 181 GNFTLKSGKNSPIYLDLRRLVTHPSILRLVAREYANVLRTLQFDRLVGLPYAALPIATAI 240

Query: 336 SLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAGLH 395
           SLEMN+PL+YPRRE K YGTK  IEGD++KGDRVV++DD+VTTG TK+EAIEKLKAAGL 
Sbjct: 241 SLEMNIPLVYPRREAKSYGTKAAIEGDYKKGDRVVVIDDIVTTGGTKLEAIEKLKAAGLE 300

Query: 396 IVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQMREVTAFMLEST 455
           IVSIVVLIDREMGAK+ LGSLGYE  AV TLSQLLPLW Q GAIT +QM++V +FM E++
Sbjct: 301 IVSIVVLIDREMGAKQLLGSLGYELEAVVTLSQLLPLWRQSGAITQQQMKDVQSFMAEAS 360

Query: 456 SKL 458
           SKL
Sbjct: 361 SKL 363
>gi|58257617|dbj|BAD88795.1| orotidine-5'-monophosphate decarboxylase and orotate
           phosphoribosyltransferase [Parabodo caudatus]
          Length = 459

 Score =  560 bits (1444), Expect = e-158,   Method: Composition-based stats.
 Identities = 279/448 (62%), Positives = 343/448 (76%), Gaps = 3/448 (0%)

Query: 4   TFFDMLNKRAKTTLLCIGLDPRADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECFGAA 63
           +FF++L KRA+ +LLC+GLDPR+   A A  EC  +I+ T+ + AAYKPNAAFFE  G  
Sbjct: 2   SFFELLEKRAERSLLCVGLDPRSKCPAGAREECISLINKTTPFVAAYKPNAAFFEALGPE 61

Query: 64  GWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDSLQP 123
           G   L +VIAH+P DIPV+LDAKRGDIADTA+AYA SAF+ L   AIT SPYMG DSL+P
Sbjct: 62  GMVVLRDVIAHVPSDIPVILDAKRGDIADTADAYALSAFKNLNAGAITVSPYMGFDSLKP 121

Query: 124 FLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVVGATDP 183
           F+    KGVFVLCKTSNKGS +LQ L     +LYE +A+  E  WN+N+NVGLVVGATDP
Sbjct: 122 FVSDRQKGVFVLCKTSNKGSDDLQTLPVGNTTLYEHVAKLVETKWNHNKNVGLVVGATDP 181

Query: 184 VALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQAKDPRAVA 243
            A++R RA AP  W L+PG+GAQGGDL+ ++  GLR D SGLLINVSRA++ A+DP   A
Sbjct: 182 SAIARVRAVAPKAWFLIPGIGAQGGDLEESVLKGLREDCSGLLINVSRAISGAQDPAQEA 241

Query: 244 QKLCEDINRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMR 303
           Q L E I +IR +  ++S+   ALV SQC RFG FTLKSG  SPIY+DLRRLV+HP IM+
Sbjct: 242 QALAERIQQIRSQKESLSK---ALVVSQCARFGTFTLKSGLISPIYLDLRRLVSHPAIMK 298

Query: 304 LVARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDF 363
           LVAR YA++L+ +++DR+VGLPYAALPI TA+SLE+N PLIYPRRE K YGTK  IEG F
Sbjct: 299 LVAREYAKVLSDIEYDRLVGLPYAALPIGTAVSLEVNKPLIYPRREAKSYGTKASIEGMF 358

Query: 364 QKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEFHAV 423
            KGDRVVI+DDLVTTGETK+EAIEKL+AAGL +V+IVVLIDR+MGA +FLGS G+ F AV
Sbjct: 359 NKGDRVVIIDDLVTTGETKIEAIEKLEAAGLKVVAIVVLIDRQMGATEFLGSRGFSFRAV 418

Query: 424 ATLSQLLPLWLQQGAITDKQMREVTAFM 451
            TL+ LL  W     I++ Q + V  F+
Sbjct: 419 TTLTDLLASWRATQVISEVQYKAVDEFL 446
>gi|71405137|ref|XP_805212.1| orotidine-5-phosphate decarboxylase/orotate
           phosphoribosyltransferase, putative [Trypanosoma cruzi
           strain CL Brener]
 gi|70868532|gb|EAN83361.1| orotidine-5-phosphate decarboxylase/orotate
           phosphoribosyltransferase, putative [Trypanosoma cruzi]
          Length = 266

 Score =  411 bits (1057), Expect = e-113,   Method: Composition-based stats.
 Identities = 198/255 (77%), Positives = 221/255 (86%)

Query: 1   MSSTFFDMLNKRAKTTLLCIGLDPRADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECF 60
           M   FFDMLN+RAK+TLLCIGLDPRA TAA A  EC R+ID T+ YAAAYKPNAAFFE F
Sbjct: 1   MPMAFFDMLNERAKSTLLCIGLDPRAKTAAEAAEECMRLIDATAEYAAAYKPNAAFFEFF 60

Query: 61  GAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDS 120
           G  GW AL++VIAH+P +IPV+LDAKRGDIADTAEAYAKSAF+ LK HAIT SPYMGGDS
Sbjct: 61  GGEGWKALQQVIAHVPANIPVILDAKRGDIADTAEAYAKSAFEHLKAHAITTSPYMGGDS 120

Query: 121 LQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVVGA 180
           L PFL+Y+SKGVFVLCKTSNKGS+E+QCL+ NG+ LYE +AE AE VWNYN+NVGLVVGA
Sbjct: 121 LSPFLQYASKGVFVLCKTSNKGSNEIQCLRVNGRHLYELVAEHAETVWNYNKNVGLVVGA 180

Query: 181 TDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQAKDPR 240
           TDP+ALSR R  APTLW LVPG+GAQGGDLKAAL AGLR DGSGLLINVSRAV +AKDPR
Sbjct: 181 TDPIALSRVRVRAPTLWFLVPGIGAQGGDLKAALNAGLRADGSGLLINVSRAVARAKDPR 240

Query: 241 AVAQKLCEDINRIRL 255
           A A+KLCEDIN +R 
Sbjct: 241 AAAKKLCEDINLVRF 255
>gi|75907180|ref|YP_321476.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Anabaena variabilis
           ATCC 29413]
 gi|75700905|gb|ABA20581.1| Orotate phosphoribosyl transferase [Anabaena variabilis ATCC 29413]
          Length = 477

 Score =  313 bits (803), Expect = 1e-83,   Method: Composition-based stats.
 Identities = 174/476 (36%), Positives = 267/476 (56%), Gaps = 33/476 (6%)

Query: 5   FFDMLNKR--AKTTLLCIGLDPRADT-----AAAAVLE-----CKRIIDTTSNYAAAYKP 52
           F D L+++     +LL +GLDP  +      ++  +++      + II  T+++  AYKP
Sbjct: 3   FSDKLHQKISQNQSLLFVGLDPNPEMMPGRYSSEDIIDGLWNWLQFIIAETADFVCAYKP 62

Query: 53  NAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITA 112
              F+E  G  G   L++ +  IP  IP++LDAK  D+ +T+  +AK+ F    V AIT 
Sbjct: 63  TLGFYEALGVPGLELLQKTLGAIPSHIPIILDAKHSDL-NTSTIFAKTVFTEWGVDAITL 121

Query: 113 SPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNR 172
           SPY G D + PFL Y  K VF+LC TSN G+  LQ   T    LY  + + ++  W    
Sbjct: 122 SPYTGQDHVAPFLVYPDKAVFILCSTSNPGAEALQQYPTRESPLYLQVVQESKN-WGTPE 180

Query: 173 NVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRA 232
            +GL VG T+   L+R R  AP   I+   + A+GG+L   L+ GL TDG+GLLI V + 
Sbjct: 181 QLGLEVGTTNAEVLARIRQVAPERIIMARSIWAEGGNLNRILEVGLDTDGNGLLIPVPQD 240

Query: 233 VTQAKDPRAVAQKLCEDINRIR-LRTNNVS------------------EMAGALVASQCV 273
           +  + +     Q L  +IN++R +   +VS                  ++   L    C+
Sbjct: 241 MLASANLSKEIQSLRAEINQVRDITVRDVSSCSVWLPDVSTVNQHPLHDLILQLYDIDCI 300

Query: 274 RFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTTMQFDRIVGLPYAALPIAT 333
            FG F   SG   P YIDLR+++++P +   V   Y  I+  + FDR+ G+PY +LP AT
Sbjct: 301 MFGNFVQASGAVFPYYIDLRKIISNPQVFNQVLSGYENIVKNLTFDRLAGIPYGSLPTAT 360

Query: 334 AISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAG 393
            ++L +N P+I+PR+E K +GT+ LIEG+F  G+ VV+VDD++ +G++ +E  +KLK+AG
Sbjct: 361 GLALRLNCPMIFPRKEVKAHGTRRLIEGNFHPGELVVVVDDILISGKSVMEGADKLKSAG 420

Query: 394 LHIVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQMREVTA 449
           L++  IVV ID E G K  L + GY  HAV T+S++  +  Q G I D+Q   +TA
Sbjct: 421 LNVHDIVVFIDHEQGVKDKLQANGYRGHAVLTISEITSVLHQAGRINDEQFLALTA 476
>gi|17230437|ref|NP_486985.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Nostoc sp. PCC 7120]
 gi|17132039|dbj|BAB74644.1| alr2945 [Nostoc sp. PCC 7120]
          Length = 500

 Score =  310 bits (793), Expect = 2e-82,   Method: Composition-based stats.
 Identities = 176/476 (36%), Positives = 270/476 (56%), Gaps = 33/476 (6%)

Query: 5   FFDML--NKRAKTTLLCIGLDPRADT-----AAAAVLE-----CKRIIDTTSNYAAAYKP 52
           FFD L  N     +LL +GLDP  +      ++  +++      + II  T+++  AYKP
Sbjct: 26  FFDKLHQNISQNQSLLFVGLDPNPEMMPGRYSSQDIIDGLWDWLQFIIAETADFVCAYKP 85

Query: 53  NAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITA 112
              F+E  G  G   L++ +A IP  IP++LDAK  D+ +T+  +AK+ F +  V AIT 
Sbjct: 86  TLGFYEALGVPGLELLQKTLAAIPSHIPIILDAKHSDL-NTSTIFAKTVFTQWGVDAITL 144

Query: 113 SPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNR 172
           SPY G D + PFL Y  K VF+LC TSN G+  LQ   T    LY  + + ++  W    
Sbjct: 145 SPYTGQDHVAPFLVYPDKAVFILCSTSNPGAEALQQYPTRESPLYLQVVQESKN-WGTPE 203

Query: 173 NVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRA 232
            +GL VG T+   L+R R  AP   I+V  + A+GG+L   L+ GL TDG+GLLI V + 
Sbjct: 204 QLGLEVGTTNAEVLARIRQVAPERMIMVRSIWAEGGNLNRILEVGLNTDGNGLLIPVPQD 263

Query: 233 VTQAKDPRAVAQKLCEDINRIR-------------------LRTNNVSEMAGALVASQCV 273
           +  + +     Q L  +IN++R                   ++ + + ++   L    C+
Sbjct: 264 MLASANLSKEIQSLRAEINQVRDITVRDVASCSVWLPDVFTVKQHPLHDLILQLYDIDCI 323

Query: 274 RFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTTMQFDRIVGLPYAALPIAT 333
            FG F   SG   P YIDLR+++++P +   V   Y  I+  + FDR+ G+PY +LP AT
Sbjct: 324 MFGNFVQASGAVFPYYIDLRKIISNPQVFNQVLSGYENIVKNLTFDRLAGIPYGSLPTAT 383

Query: 334 AISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAG 393
            ++L +N P+I+PR+E K +GT+ LIEG+F+ G+ VV+VDD++ +G++ +E  +KLK+AG
Sbjct: 384 GLALRLNCPMIFPRKEVKAHGTRRLIEGNFRTGEVVVVVDDILISGKSVMEGADKLKSAG 443

Query: 394 LHIVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQMREVTA 449
           L++  IVV ID E G K  L + GY  HAV T+S++  +  Q G I D+Q   +TA
Sbjct: 444 LNVHDIVVFIDHEQGVKDKLQANGYRGHAVLTISEITSVLHQAGRINDEQFLALTA 499
>gi|21362811|sp|Q8YSY4|PYRFE_ANASP Bifunctional enzyme pyrF/pyrE [Includes: Orotidine 5'-phosphate
           decarboxylase (OMP decarboxylase) (OMPDCase)
           (OMPdecase); Orotate phosphoribosyltransferase (OPRT)
           (OPRTase)]
          Length = 477

 Score =  309 bits (791), Expect = 3e-82,   Method: Composition-based stats.
 Identities = 176/476 (36%), Positives = 270/476 (56%), Gaps = 33/476 (6%)

Query: 5   FFDML--NKRAKTTLLCIGLDPRADT-----AAAAVLE-----CKRIIDTTSNYAAAYKP 52
           FFD L  N     +LL +GLDP  +      ++  +++      + II  T+++  AYKP
Sbjct: 3   FFDKLHQNISQNQSLLFVGLDPNPEMMPGRYSSQDIIDGLWDWLQFIIAETADFVCAYKP 62

Query: 53  NAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITA 112
              F+E  G  G   L++ +A IP  IP++LDAK  D+ +T+  +AK+ F +  V AIT 
Sbjct: 63  TLGFYEALGVPGLELLQKTLAAIPSHIPIILDAKHSDL-NTSTIFAKTVFTQWGVDAITL 121

Query: 113 SPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNR 172
           SPY G D + PFL Y  K VF+LC TSN G+  LQ   T    LY  + + ++  W    
Sbjct: 122 SPYTGQDHVAPFLVYPDKAVFILCSTSNPGAEALQQYPTRESPLYLQVVQESKN-WGTPE 180

Query: 173 NVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRA 232
            +GL VG T+   L+R R  AP   I+V  + A+GG+L   L+ GL TDG+GLLI V + 
Sbjct: 181 QLGLEVGTTNAEVLARIRQVAPERMIMVRSIWAEGGNLNRILEVGLNTDGNGLLIPVPQD 240

Query: 233 VTQAKDPRAVAQKLCEDINRIR-------------------LRTNNVSEMAGALVASQCV 273
           +  + +     Q L  +IN++R                   ++ + + ++   L    C+
Sbjct: 241 MLASANLSKEIQSLRAEINQVRDITVRDVASCSVWLPDVFTVKQHPLHDLILQLYDIDCI 300

Query: 274 RFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTTMQFDRIVGLPYAALPIAT 333
            FG F   SG   P YIDLR+++++P +   V   Y  I+  + FDR+ G+PY +LP AT
Sbjct: 301 MFGNFVQASGAVFPYYIDLRKIISNPQVFNQVLSGYENIVKNLTFDRLAGIPYGSLPTAT 360

Query: 334 AISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAG 393
            ++L +N P+I+PR+E K +GT+ LIEG+F+ G+ VV+VDD++ +G++ +E  +KLK+AG
Sbjct: 361 GLALRLNCPMIFPRKEVKAHGTRRLIEGNFRTGEVVVVVDDILISGKSVMEGADKLKSAG 420

Query: 394 LHIVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQMREVTA 449
           L++  IVV ID E G K  L + GY  HAV T+S++  +  Q G I D+Q   +TA
Sbjct: 421 LNVHDIVVFIDHEQGVKDKLQANGYRGHAVLTISEITSVLHQAGRINDEQFLALTA 476
>gi|23126878|ref|ZP_00108761.1| COG0284: Orotidine-5'-phosphate decarboxylase [Nostoc punctiforme
           PCC 73102]
          Length = 477

 Score =  305 bits (781), Expect = 4e-81,   Method: Composition-based stats.
 Identities = 173/470 (36%), Positives = 258/470 (54%), Gaps = 33/470 (7%)

Query: 5   FFDMLNKR--AKTTLLCIGLDPRADTAAA--------AVLE--CKRIIDTTSNYAAAYKP 52
           FFD LN+      +LL +GLDP  +            A LE   + II  T++Y  AYKP
Sbjct: 3   FFDKLNRSILQNQSLLFVGLDPNPEMMPVRYESEELIAGLEKWLQFIIAETADYVCAYKP 62

Query: 53  NAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITA 112
              F+E  G  G   L + +A IP  IPV+LDAK  D+ +T+  +A++ F   +V AIT 
Sbjct: 63  TLGFYEALGIPGLELLYKTLAAIPAHIPVILDAKHSDL-NTSTIFAQTVFTEWQVDAITL 121

Query: 113 SPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNR 172
           SPY G D + PFL Y  K VF+LC TSN G+  LQ   TN   LY  + + + + W    
Sbjct: 122 SPYTGQDHVAPFLVYPEKAVFILCCTSNPGAEALQQYPTNESPLYLQVVKES-KTWGTPE 180

Query: 173 NVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRA 232
            +GL VG T+   L+  RA AP   I+   + A+GG+L+  L+AGL  +G GLLI V + 
Sbjct: 181 QLGLEVGTTNAEVLALIRAIAPERIIMARSIWAKGGNLRQILEAGLNDNGDGLLIPVPQD 240

Query: 233 VTQAKDPRAVAQKLCEDINRIR-------------------LRTNNVSEMAGALVASQCV 273
           +          + L  +IN+++                   L  +   ++   L    C+
Sbjct: 241 MLGNTQLSEEVESLRAEINQLKTEIIHENSTCSVWFPDVCFLNQHPYQDLILQLYDIDCI 300

Query: 274 RFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTTMQFDRIVGLPYAALPIAT 333
            FG F   SG   P YIDLR+++++P +   V   Y  IL  + FDR+ G+PY +LP AT
Sbjct: 301 MFGSFVQASGAIFPYYIDLRKIISNPQVFNQVLTAYEDILKNLNFDRLAGIPYGSLPTAT 360

Query: 334 AISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAG 393
            ++L ++ P+I+PR+E K +GT+ +IEG+F  G+ VV+VDD++ +G++ +E   KL++AG
Sbjct: 361 GLALRLHCPMIFPRKEVKAHGTRRVIEGNFHPGETVVVVDDILISGKSVMEGAGKLESAG 420

Query: 394 LHIVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQ 443
           L++  IVVLID E G K  L   GY  H+V T+S++     Q G I ++Q
Sbjct: 421 LNVNDIVVLIDHEQGVKDRLQQNGYRSHSVLTISEITNTLYQAGRINEEQ 470
>gi|119511686|ref|ZP_01630791.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Nodularia spumigena
           CCY9414]
 gi|119463671|gb|EAW44603.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Nodularia spumigena
           CCY9414]
          Length = 479

 Score =  299 bits (766), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 174/470 (37%), Positives = 254/470 (54%), Gaps = 33/470 (7%)

Query: 5   FFDMLNKR--AKTTLLCIGLDPRADT-----AAAAVLE-----CKRIIDTTSNYAAAYKP 52
           FFD L        +LL +GLDP  +       +  V+       + II  T ++  AYKP
Sbjct: 3   FFDKLQGSISQNQSLLFVGLDPNPEMMPKHYKSQDVISDLHNWLQFIITETVDFVCAYKP 62

Query: 53  NAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITA 112
              F+E  G  G   L++ +A IP  IP++LDAK  D+ +T+  +A++ F    V AIT 
Sbjct: 63  TLGFYEALGVPGLELLQKTLAAIPSHIPIILDAKHSDL-NTSTVFARAVFTEWNVDAITL 121

Query: 113 SPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNR 172
           SPY G D + PFL Y  K VF+LC T+N G+  LQ   TN   LY  + + ++  W    
Sbjct: 122 SPYTGQDHVAPFLVYPDKAVFILCCTTNLGAEALQQYPTNESPLYLQVVKESKN-WGTPE 180

Query: 173 NVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRA 232
            +GL VG  +   L+  RA AP   I+   + A+G  L   L+AGL  +G GLLI V + 
Sbjct: 181 QLGLEVGTINAEVLALIRAVAPERIIMARSIWAEGSHLNQILEAGLSANGDGLLIPVPQD 240

Query: 233 VTQAKDPRAVAQKLCEDINR-----IRLRTNNVSEMAGALVASQ--------------CV 273
           +    +     Q L  +IN+     +R  +     +    V++Q              C+
Sbjct: 241 MLSQPNLAENIQALRAEINQGKTEIVRDASTCAVWLPDVSVSTQHPQQDLILQLYDVGCI 300

Query: 274 RFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTTMQFDRIVGLPYAALPIAT 333
            FG F   SG T P YIDLR+++++P +   V   Y  IL ++ FDR+ G+PY +LP AT
Sbjct: 301 MFGSFVQASGATFPYYIDLRKIISNPQVFNQVLSAYEEILNSLNFDRLAGIPYGSLPTAT 360

Query: 334 AISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAG 393
            +SL ++ P+IYPR+E K +GT+ LIEG F  G+ VV+VDD++ TG++ +E  EKLK+AG
Sbjct: 361 GLSLRLHCPMIYPRKEVKAHGTRRLIEGSFYPGETVVVVDDILITGKSVMEGAEKLKSAG 420

Query: 394 LHIVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQ 443
           L++  IVVLID E G +  L   GY  H+V TLS++     Q G I  +Q
Sbjct: 421 LNVQDIVVLIDHENGVQDRLLDNGYRGHSVFTLSEITETLYQAGRINQEQ 470
>gi|67924048|ref|ZP_00517498.1| Orotate phosphoribosyl transferase [Crocosphaera watsonii WH 8501]
 gi|67854115|gb|EAM49424.1| Orotate phosphoribosyl transferase [Crocosphaera watsonii WH 8501]
          Length = 481

 Score =  297 bits (760), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 169/476 (35%), Positives = 260/476 (54%), Gaps = 37/476 (7%)

Query: 5   FFDMLNKRAKTT--LLCIGLDP------------RADTAAAAVLEC--KRIIDTTSNYAA 48
           FF+ L +R  T+  LL +GLDP            +   +    LE   K +I+ T+    
Sbjct: 3   FFEKLTQRTTTSNSLLILGLDPNPEMMPQDQHTHQGQESLILALETWLKWVIEQTAELVC 62

Query: 49  AYKPNAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVH 108
           AYKP   F+E  G+ G   L +VI  IP DIP++LDAK GDI +T+  +AK+ F+  +V 
Sbjct: 63  AYKPTLGFYEALGSEGLDLLLKVIQVIPDDIPIILDAKHGDI-NTSTVFAKTIFENWQVD 121

Query: 109 AITASPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVW 168
           A+T SPY G D + PFL Y  +GVF+LC TSN G+  LQ   T+    Y  + + A + W
Sbjct: 122 AVTVSPYAGQDHIAPFLVYPDQGVFILCHTSNPGAVILQEYPTDEAPFYLQVIKEA-KTW 180

Query: 169 NYNRNVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLIN 228
                + L +G T+   + + R  AP   +L+  + ++G D+   L+  L   G G+LI 
Sbjct: 181 ATPEQLFLEIGTTNLEVIKKVRYLAPERLLLMRSIWSKGNDIHEILKVSLNPMGQGVLIP 240

Query: 229 VSRAVTQAKDPRAVAQKLCEDINRIR-------------------LRTNNVSEMAGALVA 269
           + +   ++KD +     L +DIN+ R                   L ++   ++   L  
Sbjct: 241 IPQDFLKSKDLKEKVNNLNQDINKYRKSISQNLQNCELWSPNVCLLNSHPHQDLILQLYD 300

Query: 270 SQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTTMQFDRIVGLPYAAL 329
             C+ FG++   SG T   YIDLR++++ P +   V   YA IL T+ F+RI G+PY +L
Sbjct: 301 IGCLLFGEYVQASGATFSYYIDLRKIISQPQLFHQVLNAYADILKTLNFERIAGIPYGSL 360

Query: 330 PIATAISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKL 389
           P AT +SL ++ P+IYPR+E K +GT+ LIEG FQ G++VV+VDD++ TG++  E  EKL
Sbjct: 361 PTATGLSLMLHHPMIYPRKEVKAHGTRRLIEGTFQSGEKVVVVDDILITGKSVKEGAEKL 420

Query: 390 KAAGLHIVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQMR 445
            ++GL +  IVV ID E G K  L   G   ++V T+S++     + G I ++Q +
Sbjct: 421 TSSGLIVEDIVVFIDHEQGVKDKLKEDGCNAYSVLTISEITETLYEAGRINEQQYK 476
>gi|126660262|ref|ZP_01731377.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Cyanothece sp.
           CCY0110]
 gi|126618437|gb|EAZ89191.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Cyanothece sp.
           CCY0110]
          Length = 481

 Score =  295 bits (754), Expect = 6e-78,   Method: Composition-based stats.
 Identities = 170/474 (35%), Positives = 260/474 (54%), Gaps = 37/474 (7%)

Query: 5   FFDMLNKRAKT--TLLCIGLDPRADTAAAA------------VLE--CKRIIDTTSNYAA 48
           FF+ L +R     +LL +GLDP  +                  LE   K +I+ TS    
Sbjct: 3   FFEKLTQRITNCQSLLILGLDPNPEMMPQGQHTHQEQQSLIIALEKWLKGVIEQTSGLVC 62

Query: 49  AYKPNAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVH 108
           AYKP   F+E  G+ G   L +VI  IP DIP++LDAK GDI +T+  +AK+ F++ +V 
Sbjct: 63  AYKPTLGFYEALGSKGLDLLLKVIDAIPDDIPIILDAKHGDI-NTSTIFAKTIFEQWQVD 121

Query: 109 AITASPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVW 168
           A+T SPY G D + PFL Y  +GVFVLC TSN  +  LQ   T+    Y  + + A R W
Sbjct: 122 AVTVSPYAGHDHVAPFLVYPDQGVFVLCHTSNPSAIVLQEYPTDEAPFYLQVIKEA-RTW 180

Query: 169 NYNRNVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLIN 228
                + L VG T+   + + R+ AP   +L+  + ++G D+   L+  L + G G+LI 
Sbjct: 181 ATPEQLFLEVGTTNLEVIKKIRSLAPERLLLMRSIWSKGNDIHEILKVALNSTGDGVLIP 240

Query: 229 VSRAVTQAKDPRAVAQKLCEDINRIR-------------------LRTNNVSEMAGALVA 269
           V +   ++ + +   + L ++IN  R                   L ++   ++   L  
Sbjct: 241 VPQDCLKSNNLQKDVKNLNQEINEYRQSIAQTSQNCDLWSPNVCLLNSHPHQDLILQLYD 300

Query: 270 SQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTTMQFDRIVGLPYAAL 329
             C+ FG++   SG T   YIDLR++++ P +   V   YA IL ++ FDRI G+PY +L
Sbjct: 301 IGCLLFGEYVQASGATFSYYIDLRKIISKPQLFHQVLTAYANILKSLNFDRIAGIPYGSL 360

Query: 330 PIATAISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKL 389
           P AT +SL ++ P+IYPR+E K +GT+ LIEG+F+ G++VVIVDD++ TG++  E  EKL
Sbjct: 361 PTATGLSLMLHHPMIYPRKEVKAHGTRRLIEGNFKAGEKVVIVDDILITGKSVKEGAEKL 420

Query: 390 KAAGLHIVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQ 443
            ++GL +  IVV ID E G K  L   GY  ++V T+S++     + G I ++Q
Sbjct: 421 TSSGLVVKDIVVFIDHEQGVKDKLKIEGYNAYSVLTISEITETLYEAGRINEQQ 474
>gi|119493601|ref|ZP_01624265.1| hypothetical protein L8106_17190 [Lyngbya sp. PCC 8106]
 gi|119452591|gb|EAW33774.1| hypothetical protein L8106_17190 [Lyngbya sp. PCC 8106]
          Length = 487

 Score =  273 bits (697), Expect = 2e-71,   Method: Composition-based stats.
 Identities = 167/477 (35%), Positives = 249/477 (52%), Gaps = 41/477 (8%)

Query: 5   FFDML--NKRAKTTLLCIGLDPRADTAAAAVLEC-----------KRIIDTTSNYAAAYK 51
           FFD L        +LL + LDP  ++ +    E            K ++  T +   AYK
Sbjct: 3   FFDKLIATIERNQSLLYVALDPNFESQSFNTNESQQTLEQWKDQLKSVVAQTVDVVCAYK 62

Query: 52  PNAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAIT 111
               F++ +G  G   LE+++  IP D+P++LDAK  DI +++  +A+  F++ K+ A T
Sbjct: 63  LTLGFYQAWGWQGIQLLEQILKFIPSDLPIVLDAKYSDI-NSSNIFARLIFEQWKIDACT 121

Query: 112 ASPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYN 171
            SPY G D L PFL Y  K VFVLC T+N  ++ LQ   T  QSLY  +  R  + W   
Sbjct: 122 VSPYTGLDQLTPFLVYPDKAVFVLCATANPSATILQEYPTPEQSLYLQLV-RETQTWGTL 180

Query: 172 RNVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDL------KAALQAGLRTDGSGL 225
             +GL VG      L+R R  AP   IL+ G  ++  DL       + L AGL  +  GL
Sbjct: 181 EQLGLEVGMMADT-LARVRKTAPERLILLEGDRSEENDLIEESELTSILAAGLNQNREGL 239

Query: 226 LINVSRAVTQAKDPRAVAQKLCEDINRIR-------------------LRTNNVSEMAGA 266
           L+ V   + +A++   V  +  + IN+IR                   L      ++   
Sbjct: 240 LLPVPSCLLEAENITQVVTEFRDKINKIRSQDVQGSPTCNLWLPDVCFLEHQPHRDLILQ 299

Query: 267 LVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTTMQFDRIVGLPY 326
           L    C+ FG+    SG+  P Y+DLRR+++ P I   +   YA IL  ++FDRI G+PY
Sbjct: 300 LYDIGCIIFGEHVQSSGEIFPYYVDLRRIISIPQIFHKIVSAYAEILEDLEFDRIAGIPY 359

Query: 327 AALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAI 386
            +LP AT ++L M  P+I+PR+E K YGT  LIEG FQ G+++V+VDD++ TG + +   
Sbjct: 360 GSLPTATGLALRMERPMIFPRKEVKSYGTGRLIEGHFQAGEKIVVVDDILITGNSVMRGA 419

Query: 387 EKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQ 443
           EKLK+AGL +  IVVLID   G    L S GY+ + V TL+++     Q   I+ ++
Sbjct: 420 EKLKSAGLEVEDIVVLIDHGRGVMDKLKSNGYQGYTVLTLAEIAETLYQANRISSQE 476
>gi|37520648|ref|NP_924025.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Gloeobacter violaceus
           PCC 7421]
 gi|35211642|dbj|BAC89020.1| glr1079 [Gloeobacter violaceus PCC 7421]
          Length = 484

 Score =  266 bits (680), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 180/485 (37%), Positives = 261/485 (53%), Gaps = 36/485 (7%)

Query: 5   FFDMLNKR--AKTTLLCIGLDPRAD--------TAAAAVLE--CKRIIDTTSNYAAAYKP 52
           FFD L+K    + +LL +GLDP  +        TA+ A L    + +++ T+    A+KP
Sbjct: 3   FFDKLDKAIAQQGSLLFVGLDPNPEMLPERYGRTASIAALRDWMRALVEQTAASICAFKP 62

Query: 53  NAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITA 112
              F++  G AG   L EV+  IP  +PV+LDAK GD+ +T    A++ F+   V A+T 
Sbjct: 63  TLGFYQALGPAGIDLLLEVLEWIPPHLPVILDAKHGDL-NTGTQLARTFFEDWGVDAVTI 121

Query: 113 SPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNR 172
           +P+ G D++ PFL Y  KGVFVLC T+N  +  +Q        LY+ +  R  R W    
Sbjct: 122 NPFAGQDAVAPFLLYPRKGVFVLCHTANPAAQAMQAHPGQQPPLYQQVV-REARGWGLPE 180

Query: 173 NVGLVVGATDPVALSRARACAPTLWILVPGV-GAQGGDLKAALQAGLRTDGSGLLINVSR 231
            +GL VG   P  L+R RA AP   I+V  +  A  G L + L AGL   G+GLL+ V +
Sbjct: 181 QLGLEVGTVRPEILARVRAAAPERLIMVRSLWAAPPGALASMLAAGLDAAGAGLLVPVPQ 240

Query: 232 AVTQAKDP-RAVAQKLCEDINRIR-------------------LRTNNVSEMAGALVASQ 271
               A  P  +VA   CE I  IR                   + T+ + ++A  L  + 
Sbjct: 241 ECLGADTPGLSVAALRCE-IEAIRTVPGDVPSSCTLWQPDVCLIETDRLLDLALQLFDTG 299

Query: 272 CVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARILTTMQFDRIVGLPYAALPI 331
           C+ FG++   SG   P YIDLRR++++P + + V   YA IL+T+ FDRI G+PY +LP 
Sbjct: 300 CILFGEYVQASGAVFPYYIDLRRIISNPQLFQQVLLAYAEILSTLSFDRIAGIPYGSLPT 359

Query: 332 ATAISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKLKA 391
           AT ++L +N PLI+PR+E K +GT+  IEG F  G+ VV++DD++ TG + VE   KL++
Sbjct: 360 ATGLALHLNRPLIFPRKEVKAHGTRRAIEGTFYPGETVVVIDDILITGNSAVEGARKLQS 419

Query: 392 AGLHIVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQMREVTAFM 451
            GL +  IVVLI+    A  FL S GY  +AV    ++     Q G I D Q   +    
Sbjct: 420 VGLVVRDIVVLIEHGPEASAFLQSQGYNAYAVLPFERIARTLHQAGRIDDSQYAALGEDK 479

Query: 452 LESTS 456
           L S S
Sbjct: 480 LASAS 484
>gi|113474256|ref|YP_720317.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Trichodesmium
           erythraeum IMS101]
 gi|110165304|gb|ABG49844.1| orotate phosphoribosyltransferase [Trichodesmium erythraeum IMS101]
          Length = 500

 Score =  260 bits (664), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 154/430 (35%), Positives = 223/430 (51%), Gaps = 28/430 (6%)

Query: 39  IIDTTSNYAAAYKPNAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYA 98
           +I  T  Y  AYK +  +++ FG  G   L++ +  IP +IP++LDAK  D+  T+  +A
Sbjct: 66  LITQTEKYVCAYKLSLGYYQSFGIPGLQLLQQTLKTIPSEIPIILDAKHSDL-KTSTVFA 124

Query: 99  KSAFQRLKVHAITASPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYE 158
           +S F  L+V A T  PY G D + PFL Y  K VF+LC T+N  +  LQ      Q LY 
Sbjct: 125 QSIFADLQVDACTILPYTGFDLVVPFLLYPGKAVFLLCATANASAGVLQQYPNQEQPLYL 184

Query: 159 TIAERAERVWNYNRNVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGD------LKA 212
            +   A+R W     +G  VG   P  L + R  AP   IL+ G  A+  D      L  
Sbjct: 185 KLVVEAQR-WATPEKLGFEVGIM-PDILGKIRQVAPERLILIQGDIAEENDINNPQKLNQ 242

Query: 213 ALQAGLRTDGSGLLINVSRAVTQAKDPRAVAQKLCEDINRIRLRTNNVS----------- 261
            L AGL  +G GLL+ +   +    +P+   + L   IN  RL+    S           
Sbjct: 243 LLAAGLNINGEGLLLPIPPKLLGTAEPKTAIKSLISTINEQRLKMVKGSPTCELWLPDIC 302

Query: 262 --------EMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHYARIL 313
                   ++   L    C+ FG     SG   P YIDLR++++ P I   +   YA I+
Sbjct: 303 FLQHQPHRDLILQLYNLGCIIFGDHVQASGAIFPYYIDLRKIISIPQIFHKIVTAYAEII 362

Query: 314 TTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRVVIVD 373
             ++FDRI G+PY +LP AT ++L +  P+I+PR+E K YGT  LIEG FQ G+++V+VD
Sbjct: 363 QNLEFDRIAGIPYGSLPTATGLALHLERPMIFPRKEVKAYGTGRLIEGHFQPGEKIVVVD 422

Query: 374 DLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQLLPLW 433
           D++ TG + +E  EKLK+ GL +  IVV ID E G K  L   GY  H+V TL+++    
Sbjct: 423 DIMITGNSVMEGAEKLKSVGLKVEDIVVFIDHERGVKDKLQDHGYLGHSVLTLTEIAQTL 482

Query: 434 LQQGAITDKQ 443
            +   I  +Q
Sbjct: 483 YESNKINYEQ 492
>gi|113952716|ref|YP_729596.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Synechococcus sp.
           CC9311]
 gi|113880067|gb|ABI45025.1| PyrF/pyrE bifunctional enzyme [Synechococcus sp. CC9311]
          Length = 484

 Score =  251 bits (642), Expect = 7e-65,   Method: Composition-based stats.
 Identities = 147/458 (32%), Positives = 243/458 (53%), Gaps = 48/458 (10%)

Query: 36  CKRIIDTTSNYAAAYKPNAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAE 95
           CK +I+ T+++  AYKP+  F++  G+AG   L EV   +P D+P+++D K GD+ +++ 
Sbjct: 24  CKSVIEETADHVCAYKPSLGFYQAMGSAGVELLLEVRELLPPDLPLIIDIKHGDL-NSSS 82

Query: 96  AYAKSAFQRLKVHAITASPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQS 155
           A A   FQ L   A+T +P+ G D   PFL Y  KGVF+ C +SN  + +LQ    +   
Sbjct: 83  AIAAYLFQSLHADAVTLNPFAGQDIAAPFLLYPGKGVFINCHSSNPAAHDLQHHPNDHNP 142

Query: 156 LYETIAERAERVWNYNRNVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQ 215
            Y  +  R  + W     + L VG +DP  L+  R  AP  ++++  +  + G+L+  L+
Sbjct: 143 FYLKVV-RESQSWGTPEQLLLEVGTSDPAILADVRQAAPERFVMLRSLWGEEGNLQCLLK 201

Query: 216 AGLRTDGSGLLINVSRAVTQAKDPRAVAQKLCEDINRIR--------------------- 254
            GL   G GLLI + + +    +       L   INRIR                     
Sbjct: 202 NGLNKMGDGLLIPLPQNLLNGNNINEQTSTLKGRINRIRDQHLQERAHTDAIHPEQCRIW 261

Query: 255 --------------LRTNNVS-------EMAGALVASQCVRFGKFTLKSGKTSPIYIDLR 293
                         +R + V        ++   L   +C+ FG+F   SG+    YIDLR
Sbjct: 262 PHSDQSNQDDSITTVREDGVKPIDQDLWDLVIDLYDIRCLLFGEFKQASGEIFNYYIDLR 321

Query: 294 RLVTHPLIMRLVARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDY 353
           ++++ P +   V   YA++L  ++FDRI G+PY +LP AT +SL+++ PLIYPR+E K +
Sbjct: 322 QIISDPALFHRVLDCYAQVLRPLRFDRIAGIPYGSLPTATGLSLQLHKPLIYPRKEVKAH 381

Query: 354 GTKGLIEGDFQKGDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLID----REMGA 409
           GT+ ++EG+F+KG+ V +VDD++ TG + +E I KL+++GL++  +VV +D     ++ A
Sbjct: 382 GTRRMVEGEFKKGETVAVVDDILITGGSVMEGISKLESSGLNVRDVVVFLDHGGIHDLRA 441

Query: 410 KKFLGSLGYEFHAVATLSQLLPLWLQQGAITDKQMREV 447
           K+ L S G +  AV TL  +  +      I+  Q +E+
Sbjct: 442 KQRLQSHGVKLQAVLTLDTISHVLETSDRISPDQAQEL 479
>gi|87302588|ref|ZP_01085405.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Synechococcus sp. WH
           5701]
 gi|87282932|gb|EAQ74889.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Synechococcus sp. WH
           5701]
          Length = 524

 Score =  249 bits (637), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 163/494 (32%), Positives = 249/494 (50%), Gaps = 65/494 (13%)

Query: 13  AKTTLLCIGLDP---------RADTAAAAVLE-----CKRIIDTTSNYAAAYKPNAAFFE 58
           ++ +LL  GLDP         R +  + + L       K +I+ TS+   AYKP+  F++
Sbjct: 13  SRQSLLITGLDPNPEMLQTWTRHNAGSGSFLAQARRWIKAVIEATSDSVCAYKPSLGFYQ 72

Query: 59  CFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGG 118
             G  G   L EV   +P ++P++LDAK GD+ +++ A A   F+ L V A+T SP  G 
Sbjct: 73  ALGPIGLELLREVRELVPLELPLILDAKHGDL-NSSSALAHYLFRDLGVDAVTLSPLAGQ 131

Query: 119 DSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERVWNYNRNVGLVV 178
           D   PFL Y  + V + C +SN G+  +Q        LY TI  R  ++W    ++ L V
Sbjct: 132 DIAAPFLLYPDRAVVLTCHSSNPGARVVQHHPDEDDPLYITIV-RETQLWGTPEHLLLEV 190

Query: 179 GATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRT--DGSGLLINVSRAVTQ- 235
           G +DP  L+R R  AP  ++++  +  +   L+A LQAGL    DG  L +     V + 
Sbjct: 191 GTSDPAVLARVRREAPERFLILRSLWGEEERLEALLQAGLNASADGLLLPLPQHLLVEEG 250

Query: 236 -AKDPRAVAQKL--------------CE-------------------------------D 249
            A   RA+ Q++              CE                                
Sbjct: 251 MAAGTRALRQQIETMRANWDGGTIDRCELWLPAPRVGSAAPAASSASDVLVDAKSLEQGR 310

Query: 250 INRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVARHY 309
           +   RL    + E+   L    C+ FG++   SG     YIDLRR+++ P +   V   Y
Sbjct: 311 LEDQRLEDQRLDELLVDLFDIGCLLFGEYVQASGAVFNYYIDLRRIISDPNLFHRVLHAY 370

Query: 310 ARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGDRV 369
           A  L  +QFDRI G+PY +LP AT +SL+++VPLIYPR+E K +G + LIEGDF++G+ V
Sbjct: 371 AEPLAHLQFDRIAGIPYGSLPTATGLSLQLHVPLIYPRKEVKAHGARRLIEGDFEEGETV 430

Query: 370 VIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDREMGAKKFLGSLGYEFHAVATLSQL 429
           V+VDD++ TG + +E I KL+++GL +  +VV ID    A   L S GY  HAV  + ++
Sbjct: 431 VVVDDILITGGSVLEGISKLESSGLKVQDVVVFIDHGGNASNRLASAGYACHAVVGIERI 490

Query: 430 LPLWLQQGAITDKQ 443
             + L  G ++ +Q
Sbjct: 491 TTVLLAAGRLSQEQ 504
>gi|88807296|ref|ZP_01122808.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Synechococcus sp. WH
           7805]
 gi|88788510|gb|EAR19665.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Synechococcus sp. WH
           7805]
          Length = 512

 Score =  246 bits (628), Expect = 2e-63,   Method: Composition-based stats.
 Identities = 153/502 (30%), Positives = 250/502 (49%), Gaps = 65/502 (12%)

Query: 5   FFDMLNKR--AKTTLLCIGLDPRADT----------AAAAVLE-----CKRIIDTTSNYA 47
           FF  L +   ++ +LL  GLDP  +             +++L      CK +I+ T+++ 
Sbjct: 3   FFTALTEAMGSRQSLLVTGLDPNPEMLRSWAESCGLGGSSLLSQARSWCKSVIEATADHV 62

Query: 48  AAYKPNAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKV 107
            AYKP+  F++  G+AG   + EV   +P D+P+++D K GD+ +++ A A   F+ L  
Sbjct: 63  CAYKPSLGFYQAMGSAGVELMLEVRELLPNDLPLIIDLKHGDL-NSSSAIAAYLFKTLHA 121

Query: 108 HAITASPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERV 167
            A+T +P  G D   PFL Y  KGV + C +SN G+  LQ   +  Q LY  +  R  + 
Sbjct: 122 DAVTLNPLAGQDIAAPFLLYPGKGVLINCHSSNPGARSLQHFPSEQQPLYLQVV-RESQS 180

Query: 168 WNYNRNVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGL--------- 218
           W     V L VG +DP  L+R R  AP  ++++  +  + G+L+  + +GL         
Sbjct: 181 WGTPDQVLLEVGTSDPSVLARVRKEAPERFVMLRSLWGEEGNLQRLMGSGLNATGDGLLL 240

Query: 219 ---------------------------------RTDGSGLLINVSRAVTQAKDPRAVAQK 245
                                            R D   +  N  R    A+   ++ Q 
Sbjct: 241 PLPQSLLNQDDIHEQTAALKQRINNLRQEHLVARRDSQAVPFNDCRIWPHAQSSVSMQQS 300

Query: 246 LCEDINRIRLRTNNVSEMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLV 305
           L E     +  T  + ++   L   +C+ FG+F   SG     Y+DLR++++ P + R V
Sbjct: 301 LAESDQMQQGMTQELRDLVIDLFDIRCLLFGEFKQASGAIFNYYVDLRQIISDPALFRRV 360

Query: 306 ARHYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDFQK 365
              YA++L  + F+RI G+PY +LP AT +SL+++ PLIYPR+E K +GT+ L+EG+F +
Sbjct: 361 LDCYAQVLRPLCFNRIAGIPYGSLPTATGLSLQLHKPLIYPRKEVKAHGTRRLVEGEFNE 420

Query: 366 GDRVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLID----REMGAKKFLGSLGYEFH 421
           G+ V +VDD++ TG + +E I KL  +GL +  +VV +D     +  AK+ L   G    
Sbjct: 421 GETVAVVDDILITGGSVLEGIAKLTTSGLTVSDVVVFLDHGGRHDTRAKQRLADAGLNLQ 480

Query: 422 AVATLSQLLPLWLQQGAITDKQ 443
           AV TL  +  L  + G I+ +Q
Sbjct: 481 AVLTLESIGDLLEEAGRISSRQ 502
>gi|116075686|ref|ZP_01472945.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Synechococcus sp.
           RS9916]
 gi|116067001|gb|EAU72756.1| bifunctional orotidine 5'-phosphate decarboxylase/orotate
           phosphoribosyltransferase protein [Synechococcus sp.
           RS9916]
          Length = 541

 Score =  243 bits (619), Expect = 3e-62,   Method: Composition-based stats.
 Identities = 158/504 (31%), Positives = 257/504 (50%), Gaps = 63/504 (12%)

Query: 5   FFDMLNK--RAKTTLLCIGLDPRADT----------AAAAVLE-----CKRIIDTTSNYA 47
           FF  L +   ++ +LL  GLDP  +             +++L      CK +I+ T ++ 
Sbjct: 35  FFTALTEAMTSRQSLLVTGLDPNPEMLRNWASPRGLGGSSLLSQARSWCKSVIEATEDHV 94

Query: 48  AAYKPNAAFFECFGAAGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKV 107
            AYKP+  F++  G+AG   L EV   +P D+P+++D K GD+ +++ A A   F+ L+ 
Sbjct: 95  CAYKPSLGFYQAMGSAGVELLMEVRELLPPDLPLIIDIKHGDL-NSSSAIAAYLFKTLQA 153

Query: 108 HAITASPYMGGDSLQPFLKYSSKGVFVLCKTSNKGSSELQCLQTNGQSLYETIAERAERV 167
            A+T +P  G D   PFL Y  KGV + C +SN  +  LQ      + LY  + + ++  
Sbjct: 154 DAVTLNPLAGQDIAAPFLLYPGKGVVINCHSSNPAARVLQHHPDEDRPLYLQLVKESQS- 212

Query: 168 WNYNRNVGLVVGATDPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLI 227
           W     + L VG +DP  L R R  AP  ++++  +  + G+L+  L +GL   G GLL+
Sbjct: 213 WGTPDQLLLEVGTSDPTILERVRQAAPERFVMLRSLWGEEGNLQRLLASGLNQAGDGLLL 272

Query: 228 NVSRAVTQAKDPRAVAQKLCEDINRIR-----------------------------LRTN 258
            + +++    D     + L + IN+IR                             L  +
Sbjct: 273 PLPQSLLNDSDINGQTKALKQRINQIREDHLRHQQQPDAPSDQCRIWPHAEQTPPALADS 332

Query: 259 NVS-----------EMAGALVASQCVRFGKFTLKSGKTSPIYIDLRRLVTHPLIMRLVAR 307
           N S           E+   L   +C+ FG+F   SG     Y+DLR++++ P +   V  
Sbjct: 333 NRSAVTTSIDPELRELVIDLFDIRCLLFGEFKQASGAIFNYYVDLRQIISDPALFHRVLD 392

Query: 308 HYARILTTMQFDRIVGLPYAALPIATAISLEMNVPLIYPRRERKDYGTKGLIEGDFQKGD 367
            YA++L  + FDRI G+PY +LP AT +SL+++ PLIYPR+E K +GT+ L+EG+F +G+
Sbjct: 393 CYAQVLRPLSFDRIAGIPYGSLPTATGLSLQLHKPLIYPRKEVKAHGTRRLVEGEFNEGE 452

Query: 368 RVVIVDDLVTTGETKVEAIEKLKAAGLHIVSIVVLIDR----EMGAKKFLGSLGYEFHAV 423
            V +VDD++ TG + +E I KLK +GL +  +VV +D     +  AKK L   G    AV
Sbjct: 453 TVAVVDDILITGGSVLEGIAKLKDSGLSVKDVVVFLDHGGRDDTRAKKRLEDQGLHLQAV 512

Query: 424 ATLSQLLPLWLQQGAITDKQMREV 447
            TL  +  +    G I+ +Q +E+
Sbjct: 513 LTLDTIGDVLEAAGRISPEQAQEL 536
>gi|148654371|ref|YP_001274576.1| orotidine 5'-phosphate decarboxylase [Roseiflexus sp. RS-1]
 gi|167012597|sp|A5UPS3|PYRF_ROSS1 Orotidine 5'-phosphate decarboxylase (OMP decarboxylase) (OMPDCase)
           (OMPdecase)
 gi|148566481|gb|ABQ88626.1| orotidine 5'-phosphate decarboxylase [Roseiflexus sp. RS-1]
          Length = 272

 Score =  223 bits (569), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 117/235 (49%), Positives = 152/235 (64%), Gaps = 12/235 (5%)

Query: 12  RAKTTLLCIGLDPR---------ADTAAAAVLECKRIIDTTSNYAAAYKPNAAFFECFGA 62
           R   + LCIGLDP          AD        C  I+D TS+   A+KPN AFFE FGA
Sbjct: 12  RRNRSWLCIGLDPEPMRMPVHLPADAEGVYAF-CAAIMDATSDLVCAFKPNIAFFEAFGA 70

Query: 63  AGWSALEEVIAHIPQDIPVLLDAKRGDIADTAEAYAKSAFQRLKVHAITASPYMGGDSLQ 122
           AGWSALE +I   P   P++LDAKRGDI  TAEAYA++AF+ L   A+T +PY+GGD+L+
Sbjct: 71  AGWSALERLIRLRPGP-PIILDAKRGDIGSTAEAYARAAFEVLDADAVTVNPYLGGDALE 129

Query: 123 PFLKYSSKGVFVLCKTSNKGSSELQCLQ-TNGQSLYETIAERAERVWNYNRNVGLVVGAT 181
           PFL++S +G F+LCKTSN GS +LQ ++  +G+ LY  +AE A   WN + N GLVVGAT
Sbjct: 130 PFLRHSQRGCFILCKTSNPGSHDLQDMRLADGRPLYLAVAEMARDRWNMHGNTGLVVGAT 189

Query: 182 DPVALSRARACAPTLWILVPGVGAQGGDLKAALQAGLRTDGSGLLINVSRAVTQA 236
            P A++  R   P + +LVPG+GAQGGDL   ++A    D   ++INVSR V  A
Sbjct: 190 HPTAITEVRRACPDMLLLVPGIGAQGGDLDTTVRAAAAVDEPLMMINVSRTVLYA 244