BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= XP_828584__[Trypanosoma_brucei]
(388 letters)
Database: nr.pal
6,348,806 sequences; 2,166,943,470 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71755339|ref|XP_828584.1| aspartate aminotransferase mit... 829 0.0
gi|59861162|gb|AAK73816.2|AF326990_1 mitochondrial aspartat... 825 0.0
gi|71412236|ref|XP_808313.1| aspartate aminotransferase, mi... 561 e-158
gi|157870007|ref|XP_001683554.1| aspartate aminotransferase... 407 e-112
gi|148232563|ref|NP_001080255.1| glutamate oxaloacetate tra... 405 e-111
gi|47087061|ref|NP_998544.1| glutamic-oxaloacetic transamin... 404 e-111
gi|62858411|ref|NP_001016933.1| glutamic-oxaloacetic transa... 402 e-110
gi|119500436|ref|XP_001266975.1| aspartate aminotransferase... 402 e-110
gi|66826989|ref|XP_646849.1| aspartate aminotransferase [Di... 400 e-109
gi|6980972|ref|NP_037309.1| glutamate oxaloacetate transami... 399 e-109
gi|109128739|ref|XP_001103601.1| PREDICTED: aspartate amino... 399 e-109
gi|55731048|emb|CAH92240.1| hypothetical protein [Pongo pyg... 399 e-109
gi|75042478|sp|Q5REB0|AATM_PONPY Aspartate aminotransferase... 399 e-109
gi|41053395|ref|NP_956283.1| glutamate oxaloacetate transam... 399 e-109
gi|75075926|sp|Q4R559|AATM_MACFA Aspartate aminotransferase... 398 e-109
gi|73486658|ref|NP_002071.2| aspartate aminotransferase 2 p... 398 e-109
gi|6754036|ref|NP_034455.1| glutamate oxaloacetate transami... 398 e-109
gi|114662906|ref|XP_523381.2| PREDICTED: aspartate aminotra... 398 e-109
gi|2690302|gb|AAB91426.1| aspartate aminotransferase precur... 398 e-109
gi|126305177|ref|XP_001376001.1| PREDICTED: similar to Aspa... 398 e-109
gi|62898103|dbj|BAD96991.1| aspartate aminotransferase 2 pr... 397 e-108
gi|443542|pdb|7AAT|A Chain A, X-Ray Structure Refinement An... 396 e-108
gi|12653507|gb|AAH00525.1| Glutamic-oxaloacetic transaminas... 396 e-108
gi|145258306|ref|XP_001402002.1| hypothetical protein An04g... 396 e-108
gi|67523073|ref|XP_659597.1| hypothetical protein AN1993.2 ... 395 e-108
gi|121707701|ref|XP_001271915.1| aspartate aminotransferase... 394 e-108
gi|575999|pdb|1AKA|A Chain A, Structural Basis For The Cata... 394 e-108
gi|74198651|dbj|BAE39800.1| unnamed protein product [Mus mu... 394 e-108
gi|27807377|ref|NP_777231.1| glutamic-oxaloacetic transamin... 394 e-108
gi|45382953|ref|NP_990854.1| glutamic-oxaloacetic transamin... 394 e-108
gi|158255130|dbj|BAF83536.1| unnamed protein product [Homo ... 393 e-107
gi|223867|prf||1003180A aminotransferase,Asp 393 e-107
gi|192050|gb|AAA37265.1| mitochondrial aspartate aminotrans... 393 e-107
gi|70993876|ref|XP_751785.1| aspartate aminotransferase [As... 393 e-107
gi|222979|prf||0308236A aminotransferase,Asp 392 e-107
gi|149640738|ref|XP_001507219.1| PREDICTED: similar to Aspa... 392 e-107
gi|115492715|ref|XP_001210985.1| aspartate aminotransferase... 391 e-107
gi|47522630|ref|NP_999093.1| aspartate aminotransferase 2 [... 391 e-107
gi|154338157|ref|XP_001565303.1| aspartate aminotransferase... 391 e-107
gi|71981858|ref|NP_491413.2| C44E4.3 [Caenorhabditis elegan... 390 e-107
gi|110755553|ref|XP_396131.3| PREDICTED: similar to asparta... 390 e-106
gi|154275292|ref|XP_001538497.1| aspartate aminotransferase... 389 e-106
gi|149699192|ref|XP_001495474.1| PREDICTED: similar to Aspa... 389 e-106
gi|112982|sp|P08907|AATM_HORSE Aspartate aminotransferase, ... 388 e-106
gi|119194155|ref|XP_001247681.1| aspartate aminotransferase... 387 e-106
gi|73950315|ref|XP_535278.2| PREDICTED: similar to Aspartat... 387 e-106
gi|350611|prf||0709230A transaminase,Glu oxaloacetic 387 e-106
gi|157770111|ref|XP_001676876.1| Hypothetical protein CBG05... 384 e-105
gi|91084123|ref|XP_967224.1| PREDICTED: similar to Aspartat... 381 e-104
gi|145514083|ref|XP_001442952.1| hypothetical protein GSPAT... 381 e-104
gi|25147133|ref|NP_741810.1| C14F11.1a [Caenorhabditis eleg... 380 e-104
gi|46138463|ref|XP_390922.1| hypothetical protein FG10746.1... 380 e-104
gi|118367139|ref|XP_001016785.1| aspartate aminotransferase... 380 e-104
gi|159129380|gb|EDP54494.1| aspartate transaminase, putativ... 380 e-103
gi|145514736|ref|XP_001443273.1| hypothetical protein GSPAT... 380 e-103
gi|223046|prf||0410468A aminotransferase,Asp 379 e-103
gi|71001234|ref|XP_755298.1| aspartate transaminase [Asperg... 379 e-103
gi|167520768|ref|XP_001744723.1| predicted protein [Monosig... 377 e-103
gi|119480857|ref|XP_001260457.1| aspartate transaminase, pu... 377 e-102
gi|169771579|ref|XP_001820259.1| [Aspergillus oryzae] >gi|8... 375 e-102
gi|114053127|ref|NP_001040337.1| aspartate aminotransferase... 374 e-102
gi|156401599|ref|XP_001639378.1| predicted protein [Nematos... 374 e-102
gi|50545753|ref|XP_500415.1| hypothetical protein [Yarrowia... 374 e-102
gi|46136447|ref|XP_389915.1| hypothetical protein FG09739.1... 373 e-101
gi|157745241|ref|XP_001667717.1| Hypothetical protein CBG22... 372 e-101
gi|170040614|ref|XP_001848088.1| aspartate aminotransferase... 372 e-101
gi|169783622|ref|XP_001826273.1| [Aspergillus oryzae] >gi|8... 372 e-101
gi|115748999|ref|XP_001176520.1| PREDICTED: similar to glut... 372 e-101
gi|121715326|ref|XP_001275272.1| aspartate transaminase, pu... 372 e-101
gi|154291308|ref|XP_001546238.1| glutamate oxaloacetate tra... 372 e-101
gi|156059630|ref|XP_001595738.1| aspartate aminotransferase... 370 e-101
gi|74213886|dbj|BAE29370.1| unnamed protein product [Mus mu... 370 e-100
gi|71004152|ref|XP_756742.1| hypothetical protein UM00595.1... 370 e-100
gi|118790651|ref|XP_318743.3| AGAP009685-PA [Anopheles gamb... 369 e-100
gi|66811806|ref|XP_640082.1| aspartate aminotransferase [Di... 369 e-100
gi|115748997|ref|XP_001176672.1| PREDICTED: similar to glut... 368 e-100
gi|115445217|ref|NP_001046388.1| Os02g0236000 [Oryza sativa... 368 e-100
gi|85107829|ref|XP_962457.1| aspartate aminotransferase [Ne... 367 e-100
gi|58262008|ref|XP_568414.1| aspartate aminotransferase mit... 366 1e-99
gi|157128621|ref|XP_001655159.1| aspartate aminotransferase... 366 1e-99
gi|56757419|gb|AAW26878.1| SJCHGC06163 protein [Schistosoma... 366 1e-99
gi|164660957|ref|XP_001731601.1| hypothetical protein MGL_0... 366 2e-99
gi|20599|emb|CAA45023.1| aspartate aminotransferase [Panicu... 366 2e-99
gi|125555678|gb|EAZ01284.1| hypothetical protein OsI_022516... 364 5e-99
gi|164423994|ref|XP_001728110.1| aspartate aminotransferase... 364 6e-99
gi|53792951|dbj|BAD54126.1| aspartate transaminase precurso... 364 6e-99
gi|2696240|dbj|BAA23815.1| aspartate aminotransferase [Oryz... 363 9e-99
gi|115468452|ref|NP_001057825.1| Os06g0548000 [Oryza sativa... 363 1e-98
gi|19112273|ref|NP_595481.1| aspartate aminotransferase [Sc... 363 1e-98
gi|114662908|ref|XP_001154486.1| PREDICTED: aspartate amino... 363 1e-98
gi|90075716|dbj|BAE87538.1| unnamed protein product [Macaca... 362 2e-98
gi|170085195|ref|XP_001873821.1| glutamic oxaloacetic trans... 362 2e-98
gi|15224592|ref|NP_180654.1| ASP1 (ASPARTATE AMINOTRANSFERA... 362 3e-98
gi|125986363|ref|XP_001356945.1| GA18050-PA [Drosophila pse... 362 3e-98
gi|115749001|ref|XP_796809.2| PREDICTED: similar to glutami... 362 4e-98
gi|584706|sp|P37833|AATC_ORYSJ Aspartate aminotransferase, ... 361 5e-98
gi|115440075|ref|NP_001044317.1| Os01g0760600 [Oryza sativa... 361 6e-98
gi|19571|emb|CAA43779.1| aspartate aminotransferase [Medica... 360 1e-97
gi|2506178|sp|P28011|AAT1_MEDSA Aspartate aminotransferase ... 360 1e-97
gi|20601|emb|CAA45024.1| aspartate aminotransferase [Panicu... 360 1e-97
>gi|71755339|ref|XP_828584.1| aspartate aminotransferase mitochondrial [Trypanosoma brucei
TREU927]
gi|70833970|gb|EAN79472.1| aspartate aminotransferase, mitochondrial [Trypanosoma brucei]
Length = 388
Score = 829 bits (2142), Expect = 0.0, Method: Composition-based stats.
Identities = 388/388 (100%), Positives = 388/388 (100%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQATLGTNMDYAPVTGI 60
MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQATLGTNMDYAPVTGI
Sbjct: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQATLGTNMDYAPVTGI 60
Query: 61 ASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGPDVGY 120
ASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGPDVGY
Sbjct: 61 ASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGPDVGY 120
Query: 121 PNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPTGVDPT 180
PNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPTGVDPT
Sbjct: 121 PNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPTGVDPT 180
Query: 181 HDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFSKNFG 240
HDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFSKNFG
Sbjct: 181 HDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFSKNFG 240
Query: 241 LYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTALWKK 300
LYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTALWKK
Sbjct: 241 LYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTALWKK 300
Query: 301 ELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSEYHIYM 360
ELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSEYHIYM
Sbjct: 301 ELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSEYHIYM 360
Query: 361 TLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
TLNGRAAVSGLNSTNVEYVSQAIHNVTK
Sbjct: 361 TLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
>gi|59861162|gb|AAK73816.2|AF326990_1 mitochondrial aspartate aminotransferase [Trypanosoma brucei]
Length = 388
Score = 825 bits (2132), Expect = 0.0, Method: Composition-based stats.
Identities = 386/388 (99%), Positives = 387/388 (99%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQATLGTNMDYAPVTGI 60
MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQATLGTNMDYAPVTGI
Sbjct: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQATLGTNMDYAPVTGI 60
Query: 61 ASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGPDVGY 120
ASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGPDVGY
Sbjct: 61 ASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGPDVGY 120
Query: 121 PNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPTGVDPT 180
PNHESIFAKAGMELTPYSYYDPATKG NLAGMLECLDKAPEGSVILVHACAHNPTGVDPT
Sbjct: 121 PNHESIFAKAGMELTPYSYYDPATKGLNLAGMLECLDKAPEGSVILVHACAHNPTGVDPT 180
Query: 181 HDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFSKNFG 240
HDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFSKNFG
Sbjct: 181 HDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFSKNFG 240
Query: 241 LYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTALWKK 300
LYGHRCGALH+STASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTALWKK
Sbjct: 241 LYGHRCGALHLSTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTALWKK 300
Query: 301 ELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSEYHIYM 360
ELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSEYHIYM
Sbjct: 301 ELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSEYHIYM 360
Query: 361 TLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
TLNGRAAVSGLNSTNVEYVSQAIHNVTK
Sbjct: 361 TLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
>gi|71412236|ref|XP_808313.1| aspartate aminotransferase, mitochondrial, putative [Trypanosoma
cruzi strain CL Brener]
gi|70872491|gb|EAN86462.1| aspartate aminotransferase, mitochondrial, putative [Trypanosoma
cruzi]
Length = 418
Score = 561 bits (1445), Expect = e-158, Method: Composition-based stats.
Identities = 256/388 (65%), Positives = 316/388 (81%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQATLGTNMDYAPVTGI 60
+G PD ILGL +F+ D KVNL++GVYRDDA++PFVLE VK++ G++M+YAP+ G+
Sbjct: 31 LGAPDSILGLSAEFQQDSHTPKVNLAVGVYRDDANRPFVLESVKRSDTGSDMEYAPINGM 90
Query: 61 ASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGPDVGY 120
SF++ AQKLCFG ALRDGR+ASC TLGGTGALRIGG++L+ FV +C+ IY DVGY
Sbjct: 91 RSFLKAAQKLCFGEDSRALRDGRVASCHTLGGTGALRIGGEMLHNFVNDCSNIYSSDVGY 150
Query: 121 PNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPTGVDPT 180
NH IF AG+ L PY+YY PATKG +L GML+ L+ PE SV+L+HACAHNPTGVDPT
Sbjct: 151 ANHAGIFKAAGITLPPYTYYSPATKGIDLPGMLKSLEAMPERSVVLLHACAHNPTGVDPT 210
Query: 181 HDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFSKNFG 240
++W QV DVIKRRN +PFVDMAYQGFATG +D DAF+PR LV+ VPN+IVAQSFSKNFG
Sbjct: 211 QNEWLQVVDVIKRRNLLPFVDMAYQGFATGDIDRDAFLPRCLVENVPNVIVAQSFSKNFG 270
Query: 241 LYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTALWKK 300
LYG RCGALH+ + EE R++SQ ALLIR MYSNPP+ GA +V SIL +LTALWK+
Sbjct: 271 LYGLRCGALHMVIENPEEVGRVLSQYALLIRTMYSNPPITGARIVDSILNSQELTALWKE 330
Query: 301 ELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSEYHIYM 360
EL+ MS R+ +VR+RLV EL CGSV DWSHIERQ+GMM+YTGLT+EQVE+L+ ++HIYM
Sbjct: 331 ELRAMSGRMQDVRRRLVKELGECGSVLDWSHIERQIGMMSYTGLTKEQVEMLKKKHHIYM 390
Query: 361 TLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
TLNGRAA+SGLNSTNV YV++A H+V+K
Sbjct: 391 TLNGRAAISGLNSTNVSYVAKAFHDVSK 418
>gi|157870007|ref|XP_001683554.1| aspartate aminotransferase, putative [Leishmania major]
gi|68126620|emb|CAJ04189.1| aspartate aminotransferase, putative [Leishmania major]
Length = 431
Score = 407 bits (1047), Expect = e-112, Method: Composition-based stats.
Identities = 202/393 (51%), Positives = 264/393 (67%), Gaps = 8/393 (2%)
Query: 4 PDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQAT-----LGTNMDYAPVT 58
PD I+G+ DF D KVNL IGVYRD+ ++PFVLE V++A T MDYAP+
Sbjct: 39 PDAIMGIAADFAKDMCPSKVNLCIGVYRDEQNKPFVLESVRKAMSHIVERDTQMDYAPIA 98
Query: 59 GIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNR--IYGP 116
G+ SFV Q+LCFG ++ RIAS QTL GTGAL +G LL R ++ P
Sbjct: 99 GLPSFVNSVQRLCFGKPMLDVQGDRIASAQTLSGTGALHLGVQLLQRSSGGSGTATLHIP 158
Query: 117 DVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPTG 176
YPNH +I +E + Y YY+ T N+ ML L + P GSV+L+HACAHNPTG
Sbjct: 159 SPSYPNHLNILQHLNVEASYYPYYNLNTHRLNIEAMLNYLRQLPAGSVVLLHACAHNPTG 218
Query: 177 VDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDM-VPNLIVAQSF 235
DPT ++W+Q+ DVI R + IPFVDMAYQGFATG ++ DA+V R L VP +VAQS
Sbjct: 219 CDPTPEEWQQIVDVICRSDLIPFVDMAYQGFATGDIERDAYVLRALNQQEVPTYLVAQSL 278
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+K+FGLYGHR GA+HI + +E ++SQL IR YSNPP++GA + IL+ PQL
Sbjct: 279 AKSFGLYGHRTGAVHIRCTTQKEKANVLSQLQSTIRATYSNPPIFGARIADEILRTPQLR 338
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
LWK EL QMSSR+ +VR RLV++L+ACGS DW ++E+ VGMM+ TGLT EQV L+ +
Sbjct: 339 ELWKSELNQMSSRLQDVRHRLVAQLRACGSTRDWEYLEKGVGMMSLTGLTEEQVMALQQK 398
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
Y +Y+T NGR A SGL+S NV YV+Q+IH+V++
Sbjct: 399 YSVYLTRNGRIAFSGLSSENVAYVAQSIHDVSR 431
>gi|148232563|ref|NP_001080255.1| glutamate oxaloacetate transaminase 2 [Xenopus laevis]
gi|33585662|gb|AAH56110.1| Got2 protein [Xenopus laevis]
gi|76779515|gb|AAI06355.1| Got2 protein [Xenopus laevis]
Length = 427
Score = 405 bits (1042), Expect = e-111, Method: Composition-based stats.
Identities = 191/393 (48%), Positives = 259/393 (65%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQATL---GTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y
Sbjct: 35 MGPPDPILGVTEAFKRDTNPKKMNLGVGAYRDDNGKPYVLSSVRKAEAQLASKNLDKEYL 94
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + +L G C A+++G+ + QT+ GTG+LRIG + L RF +Y
Sbjct: 95 PIGGLAEFARASAQLALGENCEAVKNGQFITVQTISGTGSLRIGANFLQRFYKYSRDVYL 154
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AG+E+ Y YYDP T GF+ AG L+ L K PE S+IL HACAHNPT
Sbjct: 155 PKPSWGNHTPIFRDAGLEVKGYRYYDPKTCGFDFAGALDDLSKIPEQSIILFHACAHNPT 214
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ + K R PF DMAYQGFA+G D DA+ RH + NL+++QS+
Sbjct: 215 GVDPKQEQWKELAALCKSRRLFPFFDMAYQGFASGDTDRDAWAVRHFIQEGINLVLSQSY 274
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + + AEEAKR+ SQ+ +LIRPMYSNPPL GA + +SIL P L
Sbjct: 275 AKNMGLYGERVGAFTVVCSDAEEAKRVESQIKILIRPMYSNPPLNGARIAASILTQPDLR 334
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M++RI +R++LVS LK GS+H+W HI Q+GM +TGL EQVE L E
Sbjct: 335 KEWLQEVKGMANRIISMREQLVSNLKKEGSIHNWQHISDQIGMFCFTGLRPEQVERLIKE 394
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S N Y++ AIH VTK
Sbjct: 395 FSIYMTKDGRISVAGVTSANNGYLAHAIHQVTK 427
>gi|47087061|ref|NP_998544.1| glutamic-oxaloacetic transaminase 2a, mitochondrial (aspartate
aminotransferase 2) [Danio rerio]
gi|68390312|ref|XP_687522.1| PREDICTED: hypothetical protein isoform 1 [Danio rerio]
gi|32451952|gb|AAH54684.1| Glutamic-oxaloacetic transaminase 2a, mitochondrial (aspartate
aminotransferase 2) [Danio rerio]
gi|94733380|emb|CAK05141.1| novel protein (zgc:66329) [Danio rerio]
Length = 428
Score = 404 bits (1037), Expect = e-111, Method: Composition-based stats.
Identities = 188/393 (47%), Positives = 263/393 (66%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQATLGT-----NMDYA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +PFVL V++A + +Y
Sbjct: 36 MGPPDPILGVTEAFKRDTNPKKMNLGVGAYRDDQGKPFVLSSVRKAEAQIAAKKLDKEYL 95
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + +L GP L+ GR + QT+ GTG+LRIG + ++RF +Y
Sbjct: 96 PIGGLADFSKACVQLALGPDNEVLKSGRSITVQTISGTGSLRIGANFVSRFHNASRDVYL 155
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH +F AGM+L Y+YY+P T GFNL G L+ + K PE SVIL+HACAHNPT
Sbjct: 156 PKPSWGNHTPVFRDAGMQLKAYTYYEPKTCGFNLKGALDDISKIPEKSVILLHACAHNPT 215
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ +IK+RN + F DMAYQGFA+G +D DA+ R+ ++ N++++QSF
Sbjct: 216 GVDPRPEQWKEMAALIKKRNLLVFFDMAYQGFASGDIDRDAWAVRYFIEQGHNILLSQSF 275
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R G + AEEAKR+ SQL +LIRP+YSNPP+ GA + ++IL P+L
Sbjct: 276 AKNMGLYGERVGGFTVVCKDAEEAKRVESQLKILIRPIYSNPPMNGARIAATILNTPELY 335
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R+ LVS LK GS H+W H+ Q+GM +TGL EQVE L +E
Sbjct: 336 KEWLQEVKGMADRIIRMREMLVSNLKKEGSTHNWQHVTDQIGMFCFTGLKPEQVERLINE 395
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S NVEY++ AIH VTK
Sbjct: 396 FSIYMTKDGRISVAGVTSANVEYLAHAIHAVTK 428
>gi|62858411|ref|NP_001016933.1| glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) [Xenopus tropicalis]
gi|89269030|emb|CAJ83961.1| glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) [Xenopus tropicalis]
Length = 427
Score = 402 bits (1034), Expect = e-110, Method: Composition-based stats.
Identities = 188/393 (47%), Positives = 258/393 (65%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQATL---GTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y
Sbjct: 35 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLSSVRKAEAQLASKNLDKEYL 94
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + +L G C A++ GR + QT+ GTG+LR+G + L RF +Y
Sbjct: 95 PIGGLAEFARASAQLALGENCDAIQSGRFITVQTISGTGSLRVGANFLQRFYKYSRDVYL 154
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AG+E+ Y YYDP T GF+ G L+ + K PE S+IL HACAHNPT
Sbjct: 155 PKPSWGNHTPIFRDAGLEVKGYRYYDPKTCGFDFTGALDDISKIPEQSIILFHACAHNPT 214
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ +IK R PF DMAYQGFA+G + DA+ RH + N++++QS+
Sbjct: 215 GVDPKQEQWKELAALIKSRRLFPFFDMAYQGFASGDTNRDAWAVRHFIQEGINVVLSQSY 274
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + + AEEAKR+ SQL +LIRPMYSNPPL GA + ++IL P L
Sbjct: 275 AKNMGLYGERVGAFTVVCSDAEEAKRVESQLKILIRPMYSNPPLNGARIAAAILTQPDLR 334
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M++RI +R++LVS LK GS+H+W HI Q+GM +TGL EQVE L E
Sbjct: 335 KEWLQEVKGMANRIISMREQLVSNLKKEGSIHNWQHISDQIGMFCFTGLRPEQVERLIKE 394
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S N Y++ AIH VTK
Sbjct: 395 FSIYMTKDGRISVAGVTSANNGYLAHAIHQVTK 427
>gi|119500436|ref|XP_001266975.1| aspartate aminotransferase, putative [Neosartorya fischeri NRRL
181]
gi|119415140|gb|EAW25078.1| aspartate aminotransferase, putative [Neosartorya fischeri NRRL
181]
Length = 429
Score = 402 bits (1032), Expect = e-110, Method: Composition-based stats.
Identities = 188/391 (48%), Positives = 258/391 (65%), Gaps = 5/391 (1%)
Query: 2 GKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YAP 56
G PD ILG+ + F+ D K K+NL +G YRDD +P+VL V+ A + + +D YA
Sbjct: 38 GPPDAILGITEAFKADTFKEKINLGVGAYRDDKGKPYVLPSVRAAEDKVVASRLDKEYAG 97
Query: 57 VTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGP 116
+TGI SF + A +L +G A +++ R+ QT+ GTGALRIGG L RF + +IY P
Sbjct: 98 ITGIPSFTKAAAELAYGSDSAVIKEDRLVITQTISGTGALRIGGAFLQRFYPHAKKIYLP 157
Query: 117 DVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPTG 176
+ NH ++F +GM++ Y YY+ T G + G++ + AP S+IL+HACAHNPTG
Sbjct: 158 TPSWANHAAVFKDSGMDVASYRYYNKDTIGLDFEGLIADIKAAPNNSIILLHACAHNPTG 217
Query: 177 VDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFS 236
VDPT D WRQ+ DV+K + H F DMAYQGFA+G D DAF PRH V N+ + QSF+
Sbjct: 218 VDPTQDQWRQISDVMKEKGHFAFFDMAYQGFASGNADRDAFAPRHFVKEGHNIALCQSFA 277
Query: 237 KNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTA 296
KN GLYG R GA + SAEE KR+ SQ+ +LIRP YSNPP++GA + S+I+ DP+L
Sbjct: 278 KNMGLYGERVGAFSLVCESAEEKKRVDSQIKILIRPFYSNPPVHGARIASTIMNDPELNQ 337
Query: 297 LWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSEY 356
W E+K M+ RI E+R L L+ GS HDWSHI Q+GM AYTGL EQ+E+L E+
Sbjct: 338 QWLGEVKGMADRIIEMRALLKKNLEDLGSKHDWSHITSQIGMFAYTGLKPEQMEVLAKEH 397
Query: 357 HIYMTLNGRAAVSGLNSTNVEYVSQAIHNVT 387
+Y T +GR +V+G+ S NV+ +++AI+ VT
Sbjct: 398 SVYATKDGRISVAGITSGNVKRLAEAIYKVT 428
>gi|66826989|ref|XP_646849.1| aspartate aminotransferase [Dictyostelium discoideum AX4]
gi|60474985|gb|EAL72921.1| aspartate aminotransferase [Dictyostelium discoideum AX4]
Length = 426
Score = 400 bits (1027), Expect = e-109, Method: Composition-based stats.
Identities = 188/392 (47%), Positives = 262/392 (66%), Gaps = 6/392 (1%)
Query: 2 GKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA-----TLGTNMDYAP 56
G DPILG+ + D + K+NL +G YRD+ +P+VL+CVK+A + +YAP
Sbjct: 34 GPEDPILGVSIAYNKDTSPSKINLGVGAYRDENGKPYVLDCVKKADKKIYEANVDHEYAP 93
Query: 57 VTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGP 116
+ G+A+F + A +L G C +++ RIA+ Q++ GTGALRI D RF+ Y P
Sbjct: 94 IVGVAAFNQLAAQLALGEECKHIKEKRIATVQSISGTGALRIAADFFARFLKG-KTAYVP 152
Query: 117 DVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPTG 176
+ + NH IF AG+ + Y YY+PAT G N M + + APEGS+IL+HACAHNPTG
Sbjct: 153 NPTWGNHNVIFNDAGIPVKSYGYYNPATCGLNFEAMTKDIAAAPEGSIILLHACAHNPTG 212
Query: 177 VDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFS 236
VDPT + W+++ ++ K R H D AYQGFA+G + DA R V+ N+ + QSF+
Sbjct: 213 VDPTAEQWKKISEICKERGHFVLFDFAYQGFASGSPEKDAAAVRMFVEDGHNIALCQSFA 272
Query: 237 KNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTA 296
KNFGLYG R GA I T ++++A + SQL +LIRPMYSNPP+YGA +V +ILKD +LT
Sbjct: 273 KNFGLYGERIGAFSILTETSDQALNVESQLKILIRPMYSNPPVYGARLVQAILKDKELTN 332
Query: 297 LWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSEY 356
W+ E+K M+ RI +R++LV LK GS DWSHI Q+GM +TGLT EQV+ L +EY
Sbjct: 333 EWRSEVKGMADRIINMREQLVKYLKKHGSTRDWSHITTQIGMFCFTGLTPEQVDRLANEY 392
Query: 357 HIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
HIY+T NGR +++G+NSTNVEY+++A+ VTK
Sbjct: 393 HIYLTRNGRISIAGINSTNVEYLAKAMAAVTK 424
>gi|6980972|ref|NP_037309.1| glutamate oxaloacetate transaminase 2 [Rattus norvegicus]
gi|112987|sp|P00507|AATM_RAT Aspartate aminotransferase, mitochondrial precursor (Transaminase
A) (Glutamate oxaloacetate transaminase 2) (mAspAT)
(Fatty acid-binding protein) (FABP-1) (FABPpm)
gi|203010|gb|AAB54275.1| aspartate aminotransferase precursor (EC 2.6.1.1)
gi|38197424|gb|AAH61792.1| Glutamate oxaloacetate transaminase 2, mitochondrial [Rattus
norvegicus]
gi|149032375|gb|EDL87266.1| rCG39016, isoform CRA_a [Rattus norvegicus]
Length = 430
Score = 399 bits (1025), Expect = e-109, Method: Composition-based stats.
Identities = 189/393 (48%), Positives = 256/393 (65%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A G N+D Y
Sbjct: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAGKNLDKEYL 97
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALR+G L RF ++
Sbjct: 98 PIGGLADFCKASAELALGENSEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFL 157
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ +G LE + K PE SV+L+HACAHNPT
Sbjct: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPT 217
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K++N F DMAYQGFA+G D DA+ RH ++ N+ + QS+
Sbjct: 218 GVDPRPEQWKEMAAVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + AEEAKR+ SQL +LIRP+YSNPPL GA + ++IL P L
Sbjct: 278 AKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLR 337
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 338 KQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKE 397
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ +YMT +GR +V+G+ S NV Y++ AIH VTK
Sbjct: 398 FSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430
>gi|109128739|ref|XP_001103601.1| PREDICTED: aspartate aminotransferase 2 [Macaca mulatta]
Length = 430
Score = 399 bits (1025), Expect = e-109, Method: Composition-based stats.
Identities = 189/393 (48%), Positives = 254/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA-----TLGTNMDYA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A T + +Y
Sbjct: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIATKNLDKEYL 97
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALRIG L RF ++
Sbjct: 98 PIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFL 157
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ G +E + K PE SV+L+HACAHNPT
Sbjct: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPT 217
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K+RN F DMAYQGFA+G D DA+ RH ++ N+ + QS+
Sbjct: 218 GVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + A+EAKR+ SQL +LIRPMYSNPPL GA + ++IL P L
Sbjct: 278 AKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLR 337
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 338 KQWLQEVKGMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLTKE 397
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S NV Y++ AIH VTK
Sbjct: 398 FSIYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430
>gi|55731048|emb|CAH92240.1| hypothetical protein [Pongo pygmaeus]
Length = 430
Score = 399 bits (1025), Expect = e-109, Method: Composition-based stats.
Identities = 190/393 (48%), Positives = 255/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y
Sbjct: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALRIG L RF ++
Sbjct: 98 PIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFL 157
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ G +E + K PE SV+L+HACAHNPT
Sbjct: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPT 217
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K+RN F DMAYQGFA+G D DA+ RH ++ N+ + QS+
Sbjct: 218 GVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + A+EAKR+ SQL +LIRPMYSNPPL GA + ++IL P L
Sbjct: 278 AKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLR 337
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 338 KTWLQEVKGMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKE 397
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S+NV Y++ AIH VTK
Sbjct: 398 FSIYMTKDGRISVAGVTSSNVGYLAHAIHQVTK 430
>gi|75042478|sp|Q5REB0|AATM_PONPY Aspartate aminotransferase, mitochondrial precursor (Transaminase
A) (Glutamate oxaloacetate transaminase 2) (mAspAT)
(Fatty acid-binding protein) (FABP-1) (FABPpm)
gi|55726250|emb|CAH89897.1| hypothetical protein [Pongo pygmaeus]
Length = 430
Score = 399 bits (1024), Expect = e-109, Method: Composition-based stats.
Identities = 190/393 (48%), Positives = 255/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y
Sbjct: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALRIG L RF ++
Sbjct: 98 PIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFL 157
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ G +E + K PE SV+L+HACAHNPT
Sbjct: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPT 217
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K+RN F DMAYQGFA+G D DA+ RH ++ N+ + QS+
Sbjct: 218 GVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + A+EAKR+ SQL +LIRPMYSNPPL GA + ++IL P L
Sbjct: 278 AKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLR 337
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 338 KQWLQEVKGMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKE 397
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S+NV Y++ AIH VTK
Sbjct: 398 FSIYMTKDGRISVAGVTSSNVGYLAHAIHQVTK 430
>gi|41053395|ref|NP_956283.1| glutamate oxaloacetate transaminase 2 [Danio rerio]
gi|29437228|gb|AAH49435.1| Glutamic-oxaloacetic transaminase 2b, mitochondrial (aspartate
aminotransferase 2) [Danio rerio]
Length = 428
Score = 399 bits (1024), Expect = e-109, Method: Composition-based stats.
Identities = 183/393 (46%), Positives = 259/393 (65%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA-----TLGTNMDYA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL CV++A + + +Y
Sbjct: 36 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLNCVRKAESLIASKALDKEYL 95
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
+ G+ F + +L G L+ R + QT+ GTG+LR+G + L+RF +Y
Sbjct: 96 GIVGLGDFNKACAELALGQDSDVLKSKRSITVQTISGTGSLRVGANFLSRFHTVARDVYL 155
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDPAT GF+ G L+ + K P+ SVIL+HACAHNPT
Sbjct: 156 PKPSWGNHTPIFRDAGMQLKAYRYYDPATCGFDFTGALDDISKIPQNSVILLHACAHNPT 215
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ VIK R +PF DMAYQGFA+G +D DA+ R+ ++ N++++QSF
Sbjct: 216 GVDPRPEQWKELSAVIKERKLLPFFDMAYQGFASGDIDRDAWAVRYFIEQGHNILLSQSF 275
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R G + AEEAKR+ SQL +LIRP+YSNPP+ GA + S+IL P+L
Sbjct: 276 AKNMGLYGERVGGFTVVCGDAEEAKRVESQLKILIRPIYSNPPMNGARIASTILTTPELR 335
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
+ W +E+K M+ RI +R+ LV+ LK GS H+W H+ Q+GM +TGL EQVE L +
Sbjct: 336 STWLEEVKGMADRIIRMREMLVTNLKKEGSTHNWQHVTDQIGMFCFTGLKPEQVERLTKD 395
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ +YMT +GR +V+G+ S NVEY++ AIH VTK
Sbjct: 396 FSVYMTKDGRISVAGVTSGNVEYLAHAIHQVTK 428
>gi|75075926|sp|Q4R559|AATM_MACFA Aspartate aminotransferase, mitochondrial precursor (Transaminase
A) (Glutamate oxaloacetate transaminase 2) (mAspAT)
(Fatty acid-binding protein) (FABP-1) (FABPpm)
gi|67970848|dbj|BAE01766.1| unnamed protein product [Macaca fascicularis]
Length = 430
Score = 398 bits (1023), Expect = e-109, Method: Composition-based stats.
Identities = 190/393 (48%), Positives = 254/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y
Sbjct: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALRIG L RF ++
Sbjct: 98 PIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFL 157
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ G +E + K PE SV+L+HACAHNPT
Sbjct: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPT 217
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K+RN F DMAYQGFA+G D DA+ RH ++ N+ + QS+
Sbjct: 218 GVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + A+EAKR+ SQL +LIRPMYSNPPL GA + ++IL P L
Sbjct: 278 AKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLR 337
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 338 KQWLQEVKGMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLTKE 397
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S NV Y++ AIH VTK
Sbjct: 398 FSIYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430
>gi|73486658|ref|NP_002071.2| aspartate aminotransferase 2 precursor [Homo sapiens]
Length = 430
Score = 398 bits (1023), Expect = e-109, Method: Composition-based stats.
Identities = 190/393 (48%), Positives = 255/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y
Sbjct: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALRIG L RF ++
Sbjct: 98 PIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFL 157
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ G +E + K PE SV+L+HACAHNPT
Sbjct: 158 PKPTWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPT 217
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K+RN F DMAYQGFA+G D DA+ RH ++ N+ + QS+
Sbjct: 218 GVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + A+EAKR+ SQL +LIRPMYSNPPL GA + ++IL P L
Sbjct: 278 AKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLR 337
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 338 KQWLQEVKVMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKE 397
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S+NV Y++ AIH VTK
Sbjct: 398 FSIYMTKDGRISVAGVTSSNVGYLAHAIHQVTK 430
>gi|6754036|ref|NP_034455.1| glutamate oxaloacetate transaminase 2, mitochondrial [Mus musculus]
gi|112984|sp|P05202|AATM_MOUSE Aspartate aminotransferase, mitochondrial precursor (Transaminase
A) (Glutamate oxaloacetate transaminase 2) (mAspAT)
(Fatty acid-binding protein) (FABP-1) (FABPpm)
gi|309110|gb|AAA37264.1| precytosolic aspartate aminotransferase (EC 2.6.1.1)
gi|872128|emb|CAA30015.1| aspartate aminotransferase [Mus musculus]
gi|57242917|gb|AAH89015.1| Glutamate oxaloacetate transaminase 2, mitochondrial [Mus musculus]
gi|58475968|gb|AAH89341.1| Glutamate oxaloacetate transaminase 2, mitochondrial [Mus musculus]
gi|74190949|dbj|BAE28248.1| unnamed protein product [Mus musculus]
gi|74196257|dbj|BAE33029.1| unnamed protein product [Mus musculus]
gi|74202117|dbj|BAE23042.1| unnamed protein product [Mus musculus]
gi|74208077|dbj|BAE29146.1| unnamed protein product [Mus musculus]
gi|74211619|dbj|BAE29171.1| unnamed protein product [Mus musculus]
gi|74225332|dbj|BAE31596.1| unnamed protein product [Mus musculus]
gi|148679242|gb|EDL11189.1| glutamate oxaloacetate transaminase 2, mitochondrial [Mus musculus]
Length = 430
Score = 398 bits (1023), Expect = e-109, Method: Composition-based stats.
Identities = 188/393 (47%), Positives = 255/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y
Sbjct: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALR+G L RF ++
Sbjct: 98 PIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRFFKFSRDVFL 157
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ +G LE + K PE SV+L+HACAHNPT
Sbjct: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPT 217
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K++N F DMAYQGFA+G D DA+ RH ++ N+ + QS+
Sbjct: 218 GVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + AEEAKR+ SQL +LIRP+YSNPPL GA + ++IL P L
Sbjct: 278 AKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLR 337
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 338 KQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKE 397
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ +YMT +GR +V+G+ S NV Y++ AIH VTK
Sbjct: 398 FSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430
>gi|114662906|ref|XP_523381.2| PREDICTED: aspartate aminotransferase 2 isoform 2 [Pan troglodytes]
gi|112983|sp|P00505|AATM_HUMAN Aspartate aminotransferase, mitochondrial precursor (Transaminase
A) (Glutamate oxaloacetate transaminase 2) (mAspAT)
(Fatty acid-binding protein) (FABP-1) (FABPpm)
gi|179104|gb|AAA35568.1| aspartate aminotransferase precursor (2.6.1.1)
gi|119603394|gb|EAW82988.1| glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2), isoform CRA_a [Homo sapiens]
gi|119603395|gb|EAW82989.1| glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2), isoform CRA_a [Homo sapiens]
Length = 430
Score = 398 bits (1023), Expect = e-109, Method: Composition-based stats.
Identities = 190/393 (48%), Positives = 255/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y
Sbjct: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALRIG L RF ++
Sbjct: 98 PIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFL 157
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ G +E + K PE SV+L+HACAHNPT
Sbjct: 158 PKPTWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPT 217
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K+RN F DMAYQGFA+G D DA+ RH ++ N+ + QS+
Sbjct: 218 GVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + A+EAKR+ SQL +LIRPMYSNPPL GA + ++IL P L
Sbjct: 278 AKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLR 337
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 338 KQWLQEVKGMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKE 397
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S+NV Y++ AIH VTK
Sbjct: 398 FSIYMTKDGRISVAGVTSSNVGYLAHAIHQVTK 430
>gi|2690302|gb|AAB91426.1| aspartate aminotransferase precursor [Mus musculus]
Length = 430
Score = 398 bits (1023), Expect = e-109, Method: Composition-based stats.
Identities = 188/393 (47%), Positives = 255/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y
Sbjct: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALR+G L RF ++
Sbjct: 98 PIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLERFFKFSRDVFL 157
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ +G LE + K PE SV+L+HACAHNPT
Sbjct: 158 PKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACAHNPT 217
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K++N F DMAYQGFA+G D DA+ RH ++ N+ + QS+
Sbjct: 218 GVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + AEEAKR+ SQL +LIRP+YSNPPL GA + ++IL P L
Sbjct: 278 AKNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLR 337
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 338 KQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKE 397
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ +YMT +GR +V+G+ S NV Y++ AIH VTK
Sbjct: 398 FSVYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 430
>gi|126305177|ref|XP_001376001.1| PREDICTED: similar to Aspartate aminotransferase, mitochondrial
precursor (Transaminase A) (Glutamate oxaloacetate
transaminase 2) [Monodelphis domestica]
Length = 421
Score = 398 bits (1022), Expect = e-109, Method: Composition-based stats.
Identities = 190/393 (48%), Positives = 255/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A G NMD Y
Sbjct: 29 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAGKNMDKEYL 88
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALR+G L RF +Y
Sbjct: 89 PIAGLAEFCKASAELALGENNEVLKSGRYVTVQTISGTGALRVGASFLQRFFKFSRDVYL 148
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ G +E + K PE SVIL+HACAHNPT
Sbjct: 149 PKPSWGNHTPIFRDAGMQLNGYRYYDPKTCGFDFTGAMEDISKIPEQSVILLHACAHNPT 208
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ ++K++ F DMAYQGFA+G + DA+ RH ++ N+ + QS+
Sbjct: 209 GVDPRPEQWKEMASLVKQKKLFAFFDMAYQGFASGDGNKDAWAVRHFIEQGINVSLCQSY 268
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + A+EAKR+ SQL +LIRPMYSNPPL GA + S+IL P L
Sbjct: 269 AKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIASTILNSPDLR 328
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
+ W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 329 SQWLQEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKE 388
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S NV Y++ AIH VTK
Sbjct: 389 FSIYMTKDGRISVAGVTSGNVGYLAHAIHQVTK 421
>gi|62898103|dbj|BAD96991.1| aspartate aminotransferase 2 precursor variant [Homo sapiens]
Length = 430
Score = 397 bits (1019), Expect = e-108, Method: Composition-based stats.
Identities = 189/393 (48%), Positives = 254/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y
Sbjct: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALRIG L RF ++
Sbjct: 98 PIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFL 157
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ G +E + K PE SV+L+HACAHNPT
Sbjct: 158 PKPTWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPT 217
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K+RN F DMAYQGFA+G D D + RH ++ N+ + QS+
Sbjct: 218 GVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDTWAVRHFIEQGINVCLCQSY 277
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + A+EAKR+ SQL +LIRPMYSNPPL GA + ++IL P L
Sbjct: 278 AKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLR 337
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 338 KQWLQEVKVMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKE 397
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S+NV Y++ AIH VTK
Sbjct: 398 FSIYMTKDGRISVAGVTSSNVGYLAHAIHQVTK 430
>gi|443542|pdb|7AAT|A Chain A, X-Ray Structure Refinement And Comparison Of Three Forms
Of Mitochondrial Aspartate Aminotransferase
gi|443543|pdb|7AAT|B Chain B, X-Ray Structure Refinement And Comparison Of Three Forms
Of Mitochondrial Aspartate Aminotransferase
gi|443556|pdb|8AAT|A Chain A, X-Ray Structure Refinement And Comparison Of Three Forms
Of Mitochondrial Aspartate Aminotransferase
gi|443557|pdb|8AAT|B Chain B, X-Ray Structure Refinement And Comparison Of Three Forms
Of Mitochondrial Aspartate Aminotransferase
gi|443572|pdb|9AAT|A Chain A, X-Ray Structure Refinement And Comparison Of Three Forms
Of Mitochondrial Aspartate Aminotransferase
gi|443573|pdb|9AAT|B Chain B, X-Ray Structure Refinement And Comparison Of Three Forms
Of Mitochondrial Aspartate Aminotransferase
gi|494624|pdb|1TAR|A Chain A, Crystalline Mitochondrial Aspartate Aminotransferase
Exists In Only Two Conformations
gi|494625|pdb|1TAR|B Chain B, Crystalline Mitochondrial Aspartate Aminotransferase
Exists In Only Two Conformations
gi|494626|pdb|1TAS|A Chain A, Crystalline Mitochondrial Aspartate Aminotransferase
Exists In Only Two Conformations
gi|494627|pdb|1TAS|B Chain B, Crystalline Mitochondrial Aspartate Aminotransferase
Exists In Only Two Conformations
gi|494628|pdb|1TAT|A Chain A, Crystalline Mitochondrial Aspartate Aminotransferase
Exists In Only Two Conformations
gi|494629|pdb|1TAT|B Chain B, Crystalline Mitochondrial Aspartate Aminotransferase
Exists In Only Two Conformations
gi|1633522|pdb|1OXO|A Chain A, Aspartate Aminotransferase, H-Asp Complex, Open
Conformation
gi|1633523|pdb|1OXO|B Chain B, Aspartate Aminotransferase, H-Asp Complex, Open
Conformation
gi|2392380|pdb|1IVR|A Chain A, Structure Of Aspartate Aminotransferase
gi|157829959|pdb|1AMA|A Chain A, Domain Closure In Mitochondrial Aspartate Aminotransferase
gi|157831931|pdb|1MAP|A Chain A, Crystal Structures Of True Enzymatic Reaction
Intermediates: Aspartate And Glutamate Ketimines In
Aspartate Aminotransferase
gi|157831932|pdb|1MAQ|A Chain A, Crystal Structures Of True Enzymatic Reaction
Intermediates: Aspartate And Glutamate Ketimines In
Aspartate Aminotransferase
gi|157832591|pdb|1OXP|A Chain A, Aspartate Aminotransferase, H-Asp Complex, Closed
Conformation
Length = 401
Score = 396 bits (1018), Expect = e-108, Method: Composition-based stats.
Identities = 184/393 (46%), Positives = 255/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL CV++A MD Y
Sbjct: 9 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLNCVRKAEAMIAAKKMDKEYL 68
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + +L G A + GR + Q + GTG+LR+G + L RF +Y
Sbjct: 69 PIAGLADFTRASAELALGENSEAFKSGRYVTVQGISGTGSLRVGANFLQRFFKFSRDVYL 128
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AG++L Y YYDP T + G +E + K PE S+IL+HACAHNPT
Sbjct: 129 PKPSWGNHTPIFRDAGLQLQAYRYYDPKTCSLDFTGAMEDISKIPEKSIILLHACAHNPT 188
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K+RN + + DMAYQGFA+G ++ DA+ RH ++ +++++QS+
Sbjct: 189 GVDPRQEQWKELASVVKKRNLLAYFDMAYQGFASGDINRDAWALRHFIEQGIDVVLSQSY 248
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + AEEAKR+ SQL +LIRPMYSNPP+ GA + S IL P+L
Sbjct: 249 AKNMGLYGERAGAFTVICRDAEEAKRVESQLKILIRPMYSNPPMNGARIASLILNTPELR 308
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 309 KEWLVEVKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKE 368
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S+NV Y++ AIH VTK
Sbjct: 369 FSIYMTKDGRISVAGVASSNVGYLAHAIHQVTK 401
>gi|12653507|gb|AAH00525.1| Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) [Homo sapiens]
gi|123981960|gb|ABM82809.1| glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) [synthetic construct]
gi|123996785|gb|ABM85994.1| glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) [synthetic construct]
Length = 430
Score = 396 bits (1018), Expect = e-108, Method: Composition-based stats.
Identities = 189/393 (48%), Positives = 254/393 (64%), Gaps = 5/393 (1%)
Query: 1 MGKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YA 55
MG PDPILG+ + F+ D +K+NL +G YRDD +P+VL V++A N+D Y
Sbjct: 38 MGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYL 97
Query: 56 PVTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYG 115
P+ G+A F + + +L G L+ GR + QT+ GTGALRIG L RF ++
Sbjct: 98 PIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFL 157
Query: 116 PDVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPT 175
P + NH IF AGM+L Y YYDP T GF+ G +E + K PE SV+L+HACAHNPT
Sbjct: 158 PKPTWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPT 217
Query: 176 GVDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSF 235
GVDP + W+++ V+K+RN F DMAYQGFA+G D DA+ RH ++ N+ + QS+
Sbjct: 218 GVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSY 277
Query: 236 SKNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLT 295
+KN GLYG R GA + A+EAKR+ SQL +LIRPMYSNPPL GA + ++IL P L
Sbjct: 278 AKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLR 337
Query: 296 ALWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSE 355
W +E+K M+ RI +R +LVS LK GS H+W HI Q+GM +TGL EQVE L E
Sbjct: 338 KQWLQEVKVMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKE 397
Query: 356 YHIYMTLNGRAAVSGLNSTNVEYVSQAIHNVTK 388
+ IYMT +GR +V+G+ S+NV Y++ AIH TK
Sbjct: 398 FSIYMTKDGRISVAGVTSSNVGYLAHAIHQATK 430
>gi|145258306|ref|XP_001402002.1| hypothetical protein An04g06380 [Aspergillus niger]
gi|134074607|emb|CAK38900.1| unnamed protein product [Aspergillus niger]
Length = 429
Score = 396 bits (1017), Expect = e-108, Method: Composition-based stats.
Identities = 185/391 (47%), Positives = 258/391 (65%), Gaps = 5/391 (1%)
Query: 2 GKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YAP 56
G PD ILG+ + ++ D K K+NL +G YRDD +P+VL V+ A + T +D YA
Sbjct: 38 GPPDAILGITEAYKADTFKEKINLGVGAYRDDQGKPYVLPSVRAAEDKVVATRLDKEYAG 97
Query: 57 VTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGP 116
+TGI +F + A +L +G A L++ R+ QT+ GTGALRIGG L RF + ++Y P
Sbjct: 98 ITGIPAFTKAAAELAYGADSAVLKEDRLVITQTISGTGALRIGGAFLQRFYPHAKKVYLP 157
Query: 117 DVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPTG 176
+ NH ++F AG+E+ Y YY+ T G + G+L + APE S+IL+HACAHNPTG
Sbjct: 158 TPSWANHAAVFKDAGLEVDKYRYYNKDTIGLDFDGLLADIKAAPENSIILLHACAHNPTG 217
Query: 177 VDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFS 236
VDPT + WRQ+ DV+K++ H F DMAYQGFA+G D DAF PRH V N+ + QSF+
Sbjct: 218 VDPTQEQWRQISDVMKQKGHFAFFDMAYQGFASGNADQDAFAPRHFVKEGHNIALCQSFA 277
Query: 237 KNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTA 296
KN GLYG R GA + SAEE KR+ SQ+ +LIRP YSNPP++GA + S+I+ D +L
Sbjct: 278 KNMGLYGERVGAFSLVCESAEEKKRVDSQIKILIRPFYSNPPIHGARIASTIMNDAKLNE 337
Query: 297 LWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSEY 356
W E+K M+ RI E+R L L+ GS HDWSHI Q+GM AYTGL EQ++ L E+
Sbjct: 338 QWLGEVKGMADRIIEMRALLRKNLEELGSKHDWSHITSQIGMFAYTGLKPEQMDALAKEH 397
Query: 357 HIYMTLNGRAAVSGLNSTNVEYVSQAIHNVT 387
+Y T +GR +V+G+ S NV+ ++++I+ +T
Sbjct: 398 SVYATKDGRISVAGITSGNVKRLAESIYKIT 428
>gi|67523073|ref|XP_659597.1| hypothetical protein AN1993.2 [Aspergillus nidulans FGSC A4]
gi|40744738|gb|EAA63894.1| hypothetical protein AN1993.2 [Aspergillus nidulans FGSC A4]
Length = 429
Score = 395 bits (1015), Expect = e-108, Method: Composition-based stats.
Identities = 185/391 (47%), Positives = 255/391 (65%), Gaps = 5/391 (1%)
Query: 2 GKPDPILGLGQDFRMDPAKRKVNLSIGVYRDDADQPFVLECVKQA---TLGTNMD--YAP 56
G PD ILG+ + ++ D K K+NL +G YRDD +P+VL V+ A + + D YA
Sbjct: 38 GPPDAILGITEAYKADSFKEKINLGVGAYRDDQGKPYVLPSVRAAEDKVVASRFDKEYAG 97
Query: 57 VTGIASFVEEAQKLCFGPTCAALRDGRIASCQTLGGTGALRIGGDLLNRFVANCNRIYGP 116
+TGI SF + A +L +G L++ R+ Q++ GTGALRIGG L RF +IY P
Sbjct: 98 ITGIPSFTKAAAQLAYGADSPVLKEDRLVITQSISGTGALRIGGAFLQRFYPGAKKIYLP 157
Query: 117 DVGYPNHESIFAKAGMELTPYSYYDPATKGFNLAGMLECLDKAPEGSVILVHACAHNPTG 176
+ NH ++F +G+E+ Y YY+ T G + G++E L AP S+IL+HACAHNPTG
Sbjct: 158 TPSWANHNAVFKDSGLEVEKYRYYNKDTIGLDFEGLVEDLKAAPNNSIILLHACAHNPTG 217
Query: 177 VDPTHDDWRQVCDVIKRRNHIPFVDMAYQGFATGQLDYDAFVPRHLVDMVPNLIVAQSFS 236
VDPT D WRQ+ +V+K + H F DMAYQGFA+G D DAF PRH V+ N+ + QSF+
Sbjct: 218 VDPTQDQWRQISNVMKEKGHFAFFDMAYQGFASGNADTDAFAPRHFVEQGHNIALCQSFA 277
Query: 237 KNFGLYGHRCGALHISTASAEEAKRLVSQLALLIRPMYSNPPLYGAWVVSSILKDPQLTA 296
KN GLYG R GA + SAEE KR+ SQ+ +LIRP YSNPP++GA V S+I+ DP L
Sbjct: 278 KNMGLYGERVGAFSLVCESAEEKKRVDSQIKILIRPFYSNPPVHGARVASTIMNDPALNK 337
Query: 297 LWKKELKQMSSRIAEVRKRLVSELKACGSVHDWSHIERQVGMMAYTGLTREQVELLRSEY 356
W E+K M+ RI E+R L L+ GS HDW+HI Q+GM AYTGL EQ+E L E+
Sbjct: 338 QWLGEVKGMADRIIEMRALLKKNLEELGSKHDWTHITSQIGMFAYTGLKPEQMEALAKEH 397
Query: 357 HIYMTLNGRAAVSGLNSTNVEYVSQAIHNVT 387
+Y T +GR +V+G+ + NV+ ++++I+ VT
Sbjct: 398 SVYATKDGRISVAGITTGNVKRLAESIYKVT 428