BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= YDR234W__[Saccharomyces_cerevisiae]
         (693 letters)

Database: nr.pal 
           6,348,806 sequences; 2,166,943,470 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6320440|ref|NP_010520.1|  Homoaconitase, catalyzes the co...  1313   0.0  
gi|51830249|gb|AAU09698.1|  YDR234W [Saccharomyces cerevisiae]   1312   0.0  
gi|151942211|gb|EDN60567.1|  homoaconitase [Saccharomyces ce...  1303   0.0  
gi|50305835|ref|XP_452878.1|  unnamed protein product [Kluyv...  1084   0.0  
gi|50292521|ref|XP_448693.1|  unnamed protein product [Candi...  1056   0.0  
gi|156846240|ref|XP_001646008.1|  hypothetical protein Kpol_...  1018   0.0  
gi|150864886|ref|XP_001383888.2|  homoaconitase [Pichia stip...   944   0.0  
gi|146419576|ref|XP_001485749.1|  hypothetical protein PGUG_...   932   0.0  
gi|50551993|ref|XP_503471.1|  hypothetical protein [Yarrowia...   928   0.0  
gi|110810414|sp|Q2HZ33|LYS4_CANPA  Homoaconitase, mitochondr...   926   0.0  
gi|68477399|ref|XP_717326.1|  homoaconitase [Candida albican...   924   0.0  
gi|50424173|ref|XP_460673.1|  hypothetical protein DEHA0F080...   914   0.0  
gi|149234467|ref|XP_001523113.1|  homoaconitase, mitochondri...   898   0.0  
gi|45185124|ref|NP_982841.1|  ABL106Cp [Ashbya gossypii ATCC...   868   0.0  
gi|19114349|ref|NP_593437.1|  homoaconitate hydratase Lys2 [...   811   0.0  
gi|67540702|ref|XP_664125.1|  LYS4_EMENI Homoaconitase, mito...   783   0.0  
gi|2492647|sp|Q92412|LYS4_EMENI  Homoaconitase, mitochondria...   777   0.0  
gi|145602518|ref|XP_359935.2|  hypothetical protein MGG_0484...   776   0.0  
gi|85091303|ref|XP_958836.1|  homoaconitase, mitochondrial p...   775   0.0  
gi|119196529|ref|XP_001248868.1|  hypothetical protein CIMG_...   772   0.0  
gi|169596725|ref|XP_001791786.1|  hypothetical protein SNOG_...   769   0.0  
gi|169776939|ref|XP_001822935.1|  [Aspergillus oryzae] >gi|1...   768   0.0  
gi|145250121|ref|XP_001396574.1|  hypothetical protein An15g...   764   0.0  
gi|46138869|ref|XP_391125.1|  hypothetical protein FG10949.1...   763   0.0  
gi|166203450|gb|ABY84678.1|  homoaconitase [Penicillium chry...   759   0.0  
gi|116205489|ref|XP_001228555.1|  hypothetical protein CHGG_...   759   0.0  
gi|154294950|ref|XP_001547913.1|  hypothetical protein BC1G_...   757   0.0  
gi|156066031|ref|XP_001598937.1|  hypothetical protein SS1G_...   751   0.0  
gi|70998032|ref|XP_753748.1|  homoaconitase LysF [Aspergillu...   739   0.0  
gi|121713108|ref|XP_001274165.1|  homoaconitase LysF [Asperg...   738   0.0  
gi|15072557|emb|CAC48042.1|  homoaconitase [Aspergillus fumi...   737   0.0  
gi|159126515|gb|EDP51631.1|  homoaconitase LysF [Aspergillus...   737   0.0  
gi|119479541|ref|XP_001259799.1|  homoaconitase LysF [Neosar...   734   0.0  
gi|115398532|ref|XP_001214855.1|  homoaconitase, mitochondri...   724   0.0  
gi|169859163|ref|XP_001836222.1|  hypothetical protein CC1G_...   696   0.0  
gi|817820|emb|CAA89720.1|  unknown [Saccharomyces cerevisiae]     684   0.0  
gi|170099323|ref|XP_001880880.1|  predicted protein [Laccari...   683   0.0  
gi|164657255|ref|XP_001729754.1|  hypothetical protein MGL_3...   660   0.0  
gi|134117387|ref|XP_772920.1|  hypothetical protein CNBK2910...   660   0.0  
gi|58260424|ref|XP_567622.1|  homoaconitate hydratase [Crypt...   659   0.0  
gi|71021417|ref|XP_760939.1|  hypothetical protein UM04792.1...   652   0.0  
gi|728689|emb|CAA88513.1|  unknown [Saccharomyces cerevisiae]     644   0.0  
gi|94969992|ref|YP_592040.1|  homoaconitase [Acidobacteria b...   578   e-163
gi|167522827|ref|XP_001745751.1|  predicted protein [Monosig...   560   e-157
gi|154276808|ref|XP_001539249.1|  homoaconitase, mitochondri...   540   e-151
gi|167749683|ref|ZP_02421810.1|  hypothetical protein EUBSIR...   238   1e-60
gi|169351397|ref|ZP_02868335.1|  hypothetical protein CLOSPI...   238   2e-60
gi|121533305|ref|ZP_01665133.1|  3-isopropylmalate dehydrata...   236   5e-60
gi|156937875|ref|YP_001435671.1|  3-isopropylmalate dehydrat...   233   4e-59
gi|169831198|ref|YP_001717180.1|  homoaconitate hydratase fa...   231   1e-58
gi|48477984|ref|YP_023690.1|  3-isopropylmalate dehydratase ...   230   3e-58
gi|153954777|ref|YP_001395542.1|  LeuC [Clostridium kluyveri...   229   7e-58
gi|163811574|ref|ZP_02203259.1|  3-isopropylmalate dehydrata...   229   7e-58
gi|11499781|ref|NP_071024.1|  3-isopropylmalate dehydratase ...   228   1e-57
gi|57234424|ref|YP_181555.1|  3-isopropylmalate dehydratase,...   227   2e-57
gi|78358259|ref|YP_389708.1|  3-isopropylmalate dehydratase,...   226   4e-57
gi|160931389|ref|ZP_02078787.1|  hypothetical protein CLOLEP...   226   5e-57
gi|34556978|ref|NP_906793.1|  3-ISOPROPYLMALATE DEHYDRATASE,...   226   5e-57
gi|153938328|ref|YP_001389789.1|  aconitase/isopropylmalate ...   225   1e-56
gi|170756378|ref|YP_001780072.1|  aconitase/isopropylmalate ...   225   1e-56
gi|91200641|emb|CAJ73691.1|  similar to 3-isopropylmalate de...   224   2e-56
gi|153931192|ref|YP_001382802.1|  aconitase/isopropylmalate ...   224   2e-56
gi|168177764|ref|ZP_02612428.1|  aconitase/isopropylmalate d...   223   3e-56
gi|15643060|ref|NP_228103.1|  3-isopropylmalate dehydratase ...   223   5e-56
gi|148378421|ref|YP_001252962.1|  aconitate hydratase [Clost...   223   6e-56
gi|146296353|ref|YP_001180124.1|  3-isopropylmalate dehydrat...   222   6e-56
gi|15643320|ref|NP_228364.1|  3-isopropylmalate dehydratase,...   222   6e-56
gi|83591075|ref|YP_431084.1|  3-isopropylmalate dehydratase ...   222   6e-56
gi|20094876|ref|NP_614723.1|  3-isopropylmalate dehydratase ...   222   8e-56
gi|148269757|ref|YP_001244217.1|  3-isopropylmalate dehydrat...   222   8e-56
gi|170288444|ref|YP_001738682.1|  3-isopropylmalate dehydrat...   222   8e-56
gi|156718858|ref|ZP_02060515.1|  homoaconitate hydratase fam...   221   1e-55
gi|148269510|ref|YP_001243970.1|  3-isopropylmalate dehydrat...   221   1e-55
gi|15606262|ref|NP_213641.1|  3-isopropylmalate dehydratase ...   221   1e-55
gi|20806559|ref|NP_621730.1|  3-isopropylmalate dehydratase ...   221   2e-55
gi|170760268|ref|YP_001785758.1|  aconitase/isopropylmalate ...   220   3e-55
gi|126698574|ref|YP_001087471.1|  3-isopropylmalate dehydrat...   220   3e-55
gi|116754297|ref|YP_843415.1|  homoaconitate hydratase famil...   219   4e-55
gi|169335473|ref|ZP_02862666.1|  hypothetical protein ANASTE...   219   4e-55
gi|168697237|ref|ZP_02729514.1|  3-isopropylmalate dehydrata...   219   4e-55
gi|15896421|ref|NP_349770.1|  3-isopropylmalate dehydratase ...   219   5e-55
gi|168181287|ref|ZP_02615951.1|  aconitase/isopropylmalate d...   219   5e-55
gi|148643360|ref|YP_001273873.1|  3-isopropylmalate dehydrat...   219   7e-55
gi|163783227|ref|ZP_02178221.1|  3-isopropylmalate dehydrata...   218   9e-55
gi|167038690|ref|YP_001661675.1|  3-isopropylmalate dehydrat...   218   1e-54
gi|160881480|ref|YP_001560448.1|  3-isopropylmalate dehydrat...   218   1e-54
gi|147920551|ref|YP_685653.1|  3-isopropylmalate dehydratase...   218   2e-54
gi|154485058|ref|ZP_02027506.1|  hypothetical protein EUBVEN...   217   2e-54
gi|147669391|ref|YP_001214209.1|  3-isopropylmalate dehydrat...   217   2e-54
gi|160940441|ref|ZP_02087786.1|  hypothetical protein CLOBOL...   217   3e-54
gi|150391195|ref|YP_001321244.1|  3-isopropylmalate dehydrat...   217   3e-54
gi|20090254|ref|NP_616329.1|  3-isopropylmalate dehydratase ...   217   3e-54
gi|18977310|ref|NP_578667.1|  3-isopropylmalate dehydratase ...   217   3e-54
gi|163816820|ref|ZP_02208183.1|  hypothetical protein COPEUT...   217   3e-54
gi|14521549|ref|NP_127025.1|  3-isopropylmalate dehydratase ...   216   4e-54
gi|15679626|ref|NP_276743.1|  3-isopropylmalate dehydratase,...   216   4e-54
gi|160942996|ref|ZP_02090234.1|  hypothetical protein FAEPRA...   216   4e-54
gi|153953599|ref|YP_001394364.1|  Aconitase-related protein ...   216   5e-54
gi|57234733|ref|YP_181192.1|  3-isopropylmalate dehydratase ...   216   5e-54
gi|84490267|ref|YP_448499.1|  LeuC1 [Methanosphaera stadtman...   216   5e-54
>gi|6320440|ref|NP_010520.1| Homoaconitase, catalyzes the conversion of homocitrate to
           homoisocitrate, which is a step in the lysine
           biosynthesis pathway; Lys4p [Saccharomyces cerevisiae]
 gi|1346476|sp|P49367|LYS4_YEAST Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|1089840|emb|CAA63764.1| homoaconitase [Saccharomyces cerevisiae]
 gi|1197581|gb|AAA88902.1| lysine biosynthesis enzyme homoaconitase [Saccharomyces cerevisiae]
          Length = 693

 Score = 1313 bits (3397), Expect = 0.0,   Method: Composition-based stats.
 Identities = 648/678 (95%), Positives = 648/678 (95%)

Query: 16  AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKI 75
           AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKI
Sbjct: 16  AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKI 75

Query: 76  KNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPL 135
           KNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPL
Sbjct: 76  KNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPL 135

Query: 136 NMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGK 195
           NMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGK
Sbjct: 136 NMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGK 195

Query: 196 DIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID 255
           DIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID
Sbjct: 196 DIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID 255

Query: 256 WYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNS 315
           WYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNS
Sbjct: 256 WYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNS 315

Query: 316 VKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYV 375
           VKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYV
Sbjct: 316 VKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYV 375

Query: 376 AAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGR 435
           AAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGR
Sbjct: 376 AAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGR 435

Query: 436 MGSKDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXXAQT 495
           MGSKD                 GKISSPAEVLSTSEIPFSGVKT             AQT
Sbjct: 436 MGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQT 495

Query: 496 EAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA 555
           EAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA
Sbjct: 496 EAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA 555

Query: 556 EFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTL 615
           EFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTL
Sbjct: 556 EFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTL 615

Query: 616 EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKN 675
           EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKN
Sbjct: 616 EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKN 675

Query: 676 LQEIIVKGGLEGWVKSQL 693
           LQEIIVKGGLEGWVKSQL
Sbjct: 676 LQEIIVKGGLEGWVKSQL 693
>gi|51830249|gb|AAU09698.1| YDR234W [Saccharomyces cerevisiae]
          Length = 693

 Score = 1312 bits (3396), Expect = 0.0,   Method: Composition-based stats.
 Identities = 647/678 (95%), Positives = 648/678 (95%)

Query: 16  AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKI 75
           AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKI
Sbjct: 16  AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKI 75

Query: 76  KNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPL 135
           KNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPL
Sbjct: 76  KNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPL 135

Query: 136 NMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGK 195
           NMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGK
Sbjct: 136 NMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGK 195

Query: 196 DIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID 255
           DIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID
Sbjct: 196 DIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID 255

Query: 256 WYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNS 315
           WYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNS
Sbjct: 256 WYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNS 315

Query: 316 VKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYV 375
           VKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYV
Sbjct: 316 VKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYV 375

Query: 376 AAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGR 435
           AAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGR
Sbjct: 376 AAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGR 435

Query: 436 MGSKDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXXAQT 495
           MGSKD                 GKISSPAEVLSTSEIPFSGVKT             AQT
Sbjct: 436 MGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQT 495

Query: 496 EAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA 555
           EAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA
Sbjct: 496 EAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA 555

Query: 556 EFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTL 615
           EFRTKVHPGDIVVSGFNFGTGSSRE+AATALLAKGINLVVSGSFGNIFSRNSINNALLTL
Sbjct: 556 EFRTKVHPGDIVVSGFNFGTGSSRERAATALLAKGINLVVSGSFGNIFSRNSINNALLTL 615

Query: 616 EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKN 675
           EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKN
Sbjct: 616 EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKN 675

Query: 676 LQEIIVKGGLEGWVKSQL 693
           LQEIIVKGGLEGWVKSQL
Sbjct: 676 LQEIIVKGGLEGWVKSQL 693
>gi|151942211|gb|EDN60567.1| homoaconitase [Saccharomyces cerevisiae YJM789]
          Length = 693

 Score = 1303 bits (3372), Expect = 0.0,   Method: Composition-based stats.
 Identities = 644/678 (94%), Positives = 644/678 (94%)

Query: 16  AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKI 75
           AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKI
Sbjct: 16  AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKI 75

Query: 76  KNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPL 135
           KNPSQIV TLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPL
Sbjct: 76  KNPSQIVNTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPL 135

Query: 136 NMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGK 195
           NM VASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGK
Sbjct: 136 NMAVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGK 195

Query: 196 DIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID 255
           DIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID
Sbjct: 196 DIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID 255

Query: 256 WYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNS 315
           WYKNRLQKLGTNNHPRINPKTIRALEEKAKI KADKDAHYAKKLIIDLATLTHYVSGPNS
Sbjct: 256 WYKNRLQKLGTNNHPRINPKTIRALEEKAKILKADKDAHYAKKLIIDLATLTHYVSGPNS 315

Query: 316 VKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYV 375
           VKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYV
Sbjct: 316 VKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYV 375

Query: 376 AAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGR 435
           AAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGR
Sbjct: 376 AAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGR 435

Query: 436 MGSKDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXXAQT 495
           MGSKD                 GKI SPAEVLSTSEIPFSGVKT             AQT
Sbjct: 436 MGSKDALAYLASPAVVAASAVLGKIGSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQT 495

Query: 496 EAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA 555
           EAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA
Sbjct: 496 EAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA 555

Query: 556 EFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTL 615
           EFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTL
Sbjct: 556 EFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTL 615

Query: 616 EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKN 675
           EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKN
Sbjct: 616 EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKN 675

Query: 676 LQEIIVKGGLEGWVKSQL 693
           LQEIIVKGGLEGWVKSQL
Sbjct: 676 LQEIIVKGGLEGWVKSQL 693
>gi|50305835|ref|XP_452878.1| unnamed protein product [Kluyveromyces lactis]
 gi|74636893|sp|Q6CT61|LYS4_KLULA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|49642011|emb|CAH01729.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
          Length = 693

 Score = 1084 bits (2804), Expect = 0.0,   Method: Composition-based stats.
 Identities = 528/680 (77%), Positives = 584/680 (85%), Gaps = 3/680 (0%)

Query: 16  AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKI 75
           A   GQN+TEKIVQ +AV LPEGK V SGDYVSIKPAHCMSHDNSWPVALKFMGLGA+ I
Sbjct: 15  ALYAGQNMTEKIVQRHAVGLPEGKTVVSGDYVSIKPAHCMSHDNSWPVALKFMGLGASTI 74

Query: 76  KNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPL 135
           KNP Q+V TLDHD+QNKSEKNLTKYKNIENFAKKH ID YPAGRGIGHQIMIEEGYAFPL
Sbjct: 75  KNPRQVVNTLDHDVQNKSEKNLTKYKNIENFAKKHGIDFYPAGRGIGHQIMIEEGYAFPL 134

Query: 136 NMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGK 195
            MTVASDSHSNTYGG+G+LGTPIVRTDAAAIWATGQTWWQIPPVAQVELKG+LP G+SGK
Sbjct: 135 TMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGELPAGISGK 194

Query: 196 DIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID 255
           DIIVALCG+FN DQVLNHAIEFTGDSL+ +PID+RLTIANMTTEWGALSGLFPVD  L+D
Sbjct: 195 DIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALSGLFPVDNVLLD 254

Query: 256 WYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNS 315
           +Y+NRL K+G NNHPRIN   I  L+ K+   +AD DA YAKKLIIDL+TLTHYVSGPNS
Sbjct: 255 FYRNRLTKVG-NNHPRINEARINELQAKSDSLQADPDAKYAKKLIIDLSTLTHYVSGPNS 313

Query: 316 VKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYV 375
           VK+S+TV DLS+QDIK+NKAYLVSCTNSRLSDL+SAA+VVCP+GD+N+V+KVA GVEFY+
Sbjct: 314 VKISSTVDDLSKQDIKVNKAYLVSCTNSRLSDLESAANVVCPSGDINQVHKVAEGVEFYI 373

Query: 376 AAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGR 435
           AAASSE+EA+AR +GAW+KLL AGC+PLP+GCGPCIGLG GLLE G+VGISATNRNFKGR
Sbjct: 374 AAASSEVEAEARATGAWQKLLNAGCLPLPAGCGPCIGLGTGLLEEGQVGISATNRNFKGR 433

Query: 436 MGSKDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGV--KTXXXXXXXXXXXXXA 493
           MGSKD                 GKI SPAEVL T +  F+GV                 A
Sbjct: 434 MGSKDALAYLASPSVVAASAILGKIGSPAEVLGTKDPNFTGVVATVEDAPATSADGKDVA 493

Query: 494 QTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENY 553
                  SVEILEGFP E SGELVLCDADNINTDGIYPGKYTYQDDVPKE MA+VCMENY
Sbjct: 494 DESGASGSVEILEGFPSEISGELVLCDADNINTDGIYPGKYTYQDDVPKETMAKVCMENY 553

Query: 554 DAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALL 613
           D +F+TK +PGDI++SGFNFGTGSSREQAATA+LAKGI LVVSGSFGNIF RNSINNALL
Sbjct: 554 DPDFQTKANPGDILISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRNSINNALL 613

Query: 614 TLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELG 673
           TLEIPALI  LR++Y+ APKELTRRTGWFLKWDV+ AKV VTEGS++GP++LEQKVGELG
Sbjct: 614 TLEIPALINMLRDRYKDAPKELTRRTGWFLKWDVSQAKVYVTEGSVNGPIVLEQKVGELG 673

Query: 674 KNLQEIIVKGGLEGWVKSQL 693
           KNLQEIIVKGGLE WVKSQL
Sbjct: 674 KNLQEIIVKGGLESWVKSQL 693
>gi|50292521|ref|XP_448693.1| unnamed protein product [Candida glabrata]
 gi|52783115|sp|Q6FM51|LYS4_CANGA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|49528005|emb|CAG61656.1| unnamed protein product [Candida glabrata CBS 138]
          Length = 689

 Score = 1056 bits (2730), Expect = 0.0,   Method: Composition-based stats.
 Identities = 515/675 (76%), Positives = 569/675 (84%), Gaps = 1/675 (0%)

Query: 19  KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNP 78
           +GQNLTEKIVQ Y+V L  GK VHSGDYVSIKPAH MSHDNSWPVALKFM LGA  +K+P
Sbjct: 16  RGQNLTEKIVQQYSVGLAPGKRVHSGDYVSIKPAHVMSHDNSWPVALKFMNLGARTVKDP 75

Query: 79  SQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMT 138
            QIV TLDHDIQNKS+KNLTKY+NIE+FAKKH ID YPAGRGIGHQIM+EEGYAFPLN+T
Sbjct: 76  RQIVNTLDHDIQNKSDKNLTKYRNIESFAKKHGIDFYPAGRGIGHQIMVEEGYAFPLNLT 135

Query: 139 VASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDII 198
           VASDSHSNTYGG+G+LGTP+VRTDAAAIWATGQTWWQIPPVAQVE KG+L + VSGKDII
Sbjct: 136 VASDSHSNTYGGMGALGTPVVRTDAAAIWATGQTWWQIPPVAQVEFKGKLHESVSGKDII 195

Query: 199 VALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           VALCG+FN DQVLNHAIEFTGD++  LP+D RLTIANMTTEWGALSGLFPVD TLI+WYK
Sbjct: 196 VALCGVFNKDQVLNHAIEFTGDAIKHLPVDFRLTIANMTTEWGALSGLFPVDDTLINWYK 255

Query: 259 NRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKV 318
           NRL  +G  NHPRIN  TI+ LE+KAK+ KAD DA YAKKL+IDL+TLTHYVSGPNSVKV
Sbjct: 256 NRLNIVGP-NHPRINETTIKNLEDKAKVFKADSDAVYAKKLVIDLSTLTHYVSGPNSVKV 314

Query: 319 SNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAA 378
           SNTVQDL++ +IKINKAYLVSCTN+RLSDL+SAA VVCPTGDL+KVNKVA GVEFY AAA
Sbjct: 315 SNTVQDLARDNIKINKAYLVSCTNARLSDLESAAKVVCPTGDLSKVNKVADGVEFYFAAA 374

Query: 379 SSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGS 438
           SSEIE +A + G W+ LL AGC PLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGS
Sbjct: 375 SSEIEKEAAEKGIWQALLAAGCKPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGS 434

Query: 439 KDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXXAQTEAP 498
           KD                 G+I SPAEV    ++  SG+                 +E  
Sbjct: 435 KDALAYLASPAVVAASAVLGRIGSPAEVWGIEDVKSSGLLAEELACNTETSTATPVSEGS 494

Query: 499 KQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFR 558
              VE+LEGFP E  GELVLCDADN+NTDGIYPGKYTYQDDV +E MAQVCMENYD EF 
Sbjct: 495 AAKVEMLEGFPEEIVGELVLCDADNVNTDGIYPGKYTYQDDVSRETMAQVCMENYDGEFG 554

Query: 559 TKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIP 618
           +K + GDI+VSGFNFGTGSSREQAAT+LLAKGINLVV+GSF N FSRNSINNALLTLEIP
Sbjct: 555 SKANAGDILVSGFNFGTGSSREQAATSLLAKGINLVVAGSFSNTFSRNSINNALLTLEIP 614

Query: 619 ALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQE 678
            L++KLR K++ APKELTRRTGWFLKWDV +AKV VTEGS DG V+LEQKVGELGKNLQE
Sbjct: 615 TLVEKLRSKFENAPKELTRRTGWFLKWDVPNAKVYVTEGSPDGQVLLEQKVGELGKNLQE 674

Query: 679 IIVKGGLEGWVKSQL 693
           II+KGGLEGWVKSQL
Sbjct: 675 IIIKGGLEGWVKSQL 689
>gi|156846240|ref|XP_001646008.1| hypothetical protein Kpol_1031p57 [Vanderwaltozyma polyspora DSM
           70294]
 gi|156116679|gb|EDO18150.1| hypothetical protein Kpol_1031p57 [Vanderwaltozyma polyspora DSM
           70294]
          Length = 689

 Score = 1018 bits (2633), Expect = 0.0,   Method: Composition-based stats.
 Identities = 498/676 (73%), Positives = 558/676 (82%), Gaps = 5/676 (0%)

Query: 19  KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNP 78
           +GQNLTEKIVQ YAV LPEGK V SGDYVSI+P++CMSHDNSWP+ALKFMGLGATK+K P
Sbjct: 17  RGQNLTEKIVQRYAVELPEGKKVFSGDYVSIRPSYCMSHDNSWPIALKFMGLGATKLKYP 76

Query: 79  SQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMT 138
            QIV TLDHD+QNKSEKNLTKY+NIENFAKKH    YPAGRGIGHQIMIEEGYAFPLN+T
Sbjct: 77  DQIVNTLDHDVQNKSEKNLTKYRNIENFAKKHGSHFYPAGRGIGHQIMIEEGYAFPLNLT 136

Query: 139 VASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDII 198
           VASDSHSN YGG+G LGTPIVRTDAA+IWATGQTWWQIPPVAQVELKG+LP GVSGKDII
Sbjct: 137 VASDSHSNIYGGVGCLGTPIVRTDAASIWATGQTWWQIPPVAQVELKGELPTGVSGKDII 196

Query: 199 VALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           VALCGLFN+DQVLNHAIEFTGDS+  L ID+RLTIANMTTEWGALSGLFPVD T+I WYK
Sbjct: 197 VALCGLFNDDQVLNHAIEFTGDSIKNLSIDNRLTIANMTTEWGALSGLFPVDSTVIQWYK 256

Query: 259 NRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKV 318
            R+ K+G  +   IN K I  LE+ A+  KAD ++ Y KKL IDL+TLT+YVSGPNSVK+
Sbjct: 257 ERINKVGEGH--IINSKAIEELEQNAQKLKADSNSKYDKKLTIDLSTLTYYVSGPNSVKI 314

Query: 319 SNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAA 378
           SN V+DLS+QDIKINKAYLVSCTNSRLSD+++AADVVCPTG++  V KVAPGV FY+AAA
Sbjct: 315 SNPVEDLSKQDIKINKAYLVSCTNSRLSDIEAAADVVCPTGNIEDVKKVAPGVNFYIAAA 374

Query: 379 SSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGS 438
           SSE+E +AR SGAW+KLLKAGCI LP+GCGPCIGLG GLLE GEVGISATNRNFKGRMGS
Sbjct: 375 SSEVEKEARTSGAWDKLLKAGCIALPAGCGPCIGLGTGLLEAGEVGISATNRNFKGRMGS 434

Query: 439 KDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXXA-QTEA 497
           KD                 GKI SP E L      ++ VKT             +  TEA
Sbjct: 435 KDALAYLASPAVVAASALAGKIVSPNEALGIESCKYASVKTSEQILEEETSGTSSGPTEA 494

Query: 498 PKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEF 557
            +  VEILEGFP E SGELV CDADNINTDGIYPGKYTYQDD+ KE MA+VCMENYD EF
Sbjct: 495 SR--VEILEGFPSEISGELVFCDADNINTDGIYPGKYTYQDDISKEMMAEVCMENYDPEF 552

Query: 558 RTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEI 617
           +TK   GDI++SGFNFGTGSSREQAAT +LA+GINLVVSGSFGNIFSRNSINN LLT+E+
Sbjct: 553 QTKTKTGDIIISGFNFGTGSSREQAATCILARGINLVVSGSFGNIFSRNSINNGLLTVEV 612

Query: 618 PALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQ 677
           P LI++LR KY+    ELTRRTGWF KWDVA+  V V EGSL G ++ EQ++ ELGKNLQ
Sbjct: 613 PKLIEQLRSKYKDDTPELTRRTGWFFKWDVANKNVTVREGSLTGTIVFEQEIPELGKNLQ 672

Query: 678 EIIVKGGLEGWVKSQL 693
           EIIVKGGLEGWVKS+L
Sbjct: 673 EIIVKGGLEGWVKSKL 688
>gi|150864886|ref|XP_001383888.2| homoaconitase [Pichia stipitis CBS 6054]
 gi|149386142|gb|ABN65859.2| homoaconitase [Pichia stipitis CBS 6054]
          Length = 677

 Score =  944 bits (2439), Expect = 0.0,   Method: Composition-based stats.
 Identities = 475/682 (69%), Positives = 548/682 (80%), Gaps = 30/682 (4%)

Query: 18  LKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKN 77
           L+GQNLTEKIVQ YAVNLP GK V SGDYVSIKPAHCMSHDNSWPVA KFMGLGATK+K+
Sbjct: 16  LRGQNLTEKIVQRYAVNLPAGKQVFSGDYVSIKPAHCMSHDNSWPVATKFMGLGATKVKD 75

Query: 78  PSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNM 137
             QIV TLDHD+QNKSEKNL KY+NIE FAK+  ID YPAGRGIGHQIMIEEGYAFPLN+
Sbjct: 76  NRQIVCTLDHDVQNKSEKNLEKYRNIEQFAKEQGIDFYPAGRGIGHQIMIEEGYAFPLNL 135

Query: 138 TVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDI 197
           TVASDSHSNTYGG+GSLGTPIVRTDAA+IWATGQTWWQIPPVA+VEL+G+LP GV+GKDI
Sbjct: 136 TVASDSHSNTYGGVGSLGTPIVRTDAASIWATGQTWWQIPPVAKVELQGKLPAGVTGKDI 195

Query: 198 IVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWY 257
           IVALCG FN D+VLNHAIEF GD +  L ID+RLTIANMTTEWGALSGLFPVD  L+DWY
Sbjct: 196 IVALCGAFNKDEVLNHAIEFVGDGIEHLSIDYRLTIANMTTEWGALSGLFPVDARLLDWY 255

Query: 258 KN-RLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSV 316
           ++ RL KLG+  HPR+N KT+ ALE+     ++D DA YAK L++DL++LT Y+SGPNSV
Sbjct: 256 RSERLAKLGS-GHPRVNDKTVSALEKNPV--QSDSDAVYAKHLVVDLSSLTPYISGPNSV 312

Query: 317 KVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVA 376
           K+SN++ DL +QDI INKAYLVSCTNSRLSD+Q+AADV+       + +KVAPGVEFYVA
Sbjct: 313 KISNSLADLVEQDIPINKAYLVSCTNSRLSDIQAAADVI-------RGHKVAPGVEFYVA 365

Query: 377 AASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRM 436
           AASS ++ DA  +GAW+ +L+AG  PLP+GCGPCIGLG GLL+ GEVGISATNRNFKGRM
Sbjct: 366 AASSNVQKDAEAAGAWKTILEAGAKPLPAGCGPCIGLGTGLLKDGEVGISATNRNFKGRM 425

Query: 437 GSKDXXXXXXXXXXXXXXXXXGKISSPAE-----VLSTSEIPFSGVKTXXXXXXXXXXXX 491
           GSKD                 G+I  P E     VLST EI    +KT            
Sbjct: 426 GSKDALAYLASPEVVAASAVLGRIGGPQELEGKSVLSTREI----IKT-------IEETK 474

Query: 492 XAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCME 551
            ++  A   +VE+LEGFP+   GEL+LCDADNINTDGIYPGKYTYQDD+P+EKMA+VCME
Sbjct: 475 VSEDAATGGAVEVLEGFPKVIEGELILCDADNINTDGIYPGKYTYQDDIPREKMAEVCME 534

Query: 552 NYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNA 611
           NYDAEF  K   GDI++SG+NFGTGSSREQAATA+LA+G+ LVV+GSFGNIFSRNSINNA
Sbjct: 535 NYDAEFNGKTKAGDIIISGYNFGTGSSREQAATAILARGMKLVVAGSFGNIFSRNSINNA 594

Query: 612 LLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGE 671
           LLTLEIP LI  LR KY G+  ELT RTGW LKWDV  A V V +   +G V+L+QKVGE
Sbjct: 595 LLTLEIPDLINNLRAKYAGS-DELTVRTGWILKWDVTTATVEVKDS--EGNVVLKQKVGE 651

Query: 672 LGKNLQEIIVKGGLEGWVKSQL 693
           LG NLQ+IIVKGGLEGWV+S+L
Sbjct: 652 LGTNLQDIIVKGGLEGWVRSEL 673
>gi|146419576|ref|XP_001485749.1| hypothetical protein PGUG_01420 [Pichia guilliermondii ATCC 6260]
 gi|146389164|gb|EDK37322.1| hypothetical protein PGUG_01420 [Pichia guilliermondii ATCC 6260]
          Length = 674

 Score =  932 bits (2409), Expect = 0.0,   Method: Composition-based stats.
 Identities = 461/676 (68%), Positives = 540/676 (79%), Gaps = 16/676 (2%)

Query: 18  LKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKN 77
           L+GQNLTEKIVQ YAV +  GK V SGDYV+IKPAHCMSHDNSWPVA KFMGLGATK+K+
Sbjct: 14  LRGQNLTEKIVQKYAVGVAPGKKVVSGDYVTIKPAHCMSHDNSWPVATKFMGLGATKVKD 73

Query: 78  PSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNM 137
             Q+V TLDHD+QN+SE N+ KY NIE FA +  ID YPAGRGIGHQIMIEEGYAFP N+
Sbjct: 74  NRQVVCTLDHDVQNRSESNMKKYANIEKFATEQGIDFYPAGRGIGHQIMIEEGYAFPHNL 133

Query: 138 TVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDI 197
           TVASD HSNTYGG+GSLGTPIVRTDAAAIWATGQTWWQIPPVA+VE  G+L +GV+GKD+
Sbjct: 134 TVASDLHSNTYGGVGSLGTPIVRTDAAAIWATGQTWWQIPPVAKVEFTGELSEGVTGKDV 193

Query: 198 IVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWY 257
           IVALCG+FN D+VLNHAIEF GD + +LPID+RLTIANMTTEWGALSGLFPVD+T+ID+Y
Sbjct: 194 IVALCGVFNQDEVLNHAIEFVGDGVKSLPIDYRLTIANMTTEWGALSGLFPVDQTVIDFY 253

Query: 258 KNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
           + R+Q+L    H RIN  T+  L   AK   AD DA YAK LI+DL+T++  VSGPNSVK
Sbjct: 254 EGRMQRL-QQPHERINSDTVGKLAANAKEMAADSDAKYAKHLIVDLSTISPCVSGPNSVK 312

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAA 377
           V++++ DL+QQDIKINKAYLVSCTNSRLSD+Q+AAD+V       + + +A GVEFYVAA
Sbjct: 313 VASSLHDLAQQDIKINKAYLVSCTNSRLSDIQAAADIV-------RGHTIADGVEFYVAA 365

Query: 378 ASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMG 437
           ASS+++ DA  +GAW+ ++ AG  PLP+GCGPCIGLG GLLEPGEVGISATNRNFKGRMG
Sbjct: 366 ASSQVQQDAEAAGAWQTIIDAGAKPLPAGCGPCIGLGTGLLEPGEVGISATNRNFKGRMG 425

Query: 438 SKDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXXAQTEA 497
           SKD                 G+I  P E+ S S+I                    ++  A
Sbjct: 426 SKDALAYLASPEVVAASAILGRIGGPEEI-SGSKI----AAPATLKRSTSVSTSDSEDSA 480

Query: 498 PKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEF 557
               V+I+ GFP+E +GEL+LC+ADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYD EF
Sbjct: 481 TGAGVDIIPGFPQELTGELILCNADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDGEF 540

Query: 558 RTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEI 617
            +K  PGDI++SG+NFGTGSSREQAATA+LA+G+ LVV+GSFGNIFSRNSINNALLTLEI
Sbjct: 541 YSKTKPGDIIISGYNFGTGSSREQAATAILARGMQLVVAGSFGNIFSRNSINNALLTLEI 600

Query: 618 PALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQ 677
           PALI KLR+KY G  KELT RTGWFLKWDV  A+V VT+   D  VI++QKVGELG NLQ
Sbjct: 601 PALIDKLRQKYAG-DKELTIRTGWFLKWDVPKAQVTVTDA--DNKVIMQQKVGELGTNLQ 657

Query: 678 EIIVKGGLEGWVKSQL 693
           +IIVKGGLEGWVK+Q+
Sbjct: 658 DIIVKGGLEGWVKAQI 673
>gi|50551993|ref|XP_503471.1| hypothetical protein [Yarrowia lipolytica]
 gi|74634036|sp|Q6C791|LYS4_YARLI Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|49649340|emb|CAG79050.1| unnamed protein product [Yarrowia lipolytica CLIB122]
          Length = 687

 Score =  928 bits (2398), Expect = 0.0,   Method: Composition-based stats.
 Identities = 460/675 (68%), Positives = 531/675 (78%), Gaps = 14/675 (2%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           QNLTEKIVQ YAV LPEGK V SGDYVSI+P+HCM+HDNSWPVA KF GLGA  +K+  Q
Sbjct: 25  QNLTEKIVQRYAVGLPEGKQVQSGDYVSIRPSHCMTHDNSWPVATKFKGLGAKAVKDNRQ 84

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QNKSEKNL KY NIENFA +  ID YPAGRGIGHQ+M+EEGYAFP N+TVA
Sbjct: 85  VVMTLDHDVQNKSEKNLEKYANIENFAGEQGIDFYPAGRGIGHQVMVEEGYAFPYNLTVA 144

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTPIVRTDAA++WATGQTWWQIPPVA+VELKGQLP GV GKD+I+A
Sbjct: 145 SDSHSNMYGGIGCLGTPIVRTDAASVWATGQTWWQIPPVARVELKGQLPAGVFGKDVIIA 204

Query: 201 LCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNR 260
           LCG+FNND+VLNHAIEF GD +  L +D RLTIANMTTEWGAL+GLFPVD+TL  WY+ R
Sbjct: 205 LCGIFNNDEVLNHAIEFVGDGVEHLSVDERLTIANMTTEWGALTGLFPVDETLRQWYEYR 264

Query: 261 LQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVSN 320
           L +L    H R+N  T+ AL++     +AD DA YAK L IDL+TL+ ++SGPNSVKV N
Sbjct: 265 LTRL-PQPHARVNDGTVAALKDAV---QADTDAKYAKNLTIDLSTLSPFLSGPNSVKVYN 320

Query: 321 TVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASS 380
           ++ DLS QDIKINKAYLVSCTNSRLSD+++AA+V+       K NKVA GVEFYVAAASS
Sbjct: 321 SLADLSAQDIKINKAYLVSCTNSRLSDIEAAANVI-------KNNKVAEGVEFYVAAASS 373

Query: 381 EIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKD 440
            ++ DA  SGAW+ L+ AG  PLP+GCGPCIGLG GLLE GEVGISATNRNFKGRMGSKD
Sbjct: 374 FVQKDAEASGAWQTLINAGAKPLPAGCGPCIGLGTGLLEDGEVGISATNRNFKGRMGSKD 433

Query: 441 XXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXXAQTEA--P 498
                            GKI  P EV  +      GV +             A+     P
Sbjct: 434 ALAYLASPEVVAASAVLGKIGFPEEVYGSPVPGAKGVSSSISVTEAVEAEADAEAAESDP 493

Query: 499 KQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFR 558
             S  +L+GFP + +GELVLCDADNINTDGIYPGKYTYQDDVP+EKMA+VCMENYD +F 
Sbjct: 494 APSGGVLDGFPAQITGELVLCDADNINTDGIYPGKYTYQDDVPREKMAEVCMENYDPDFG 553

Query: 559 TKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIP 618
           +K   GDI+VSGFNFGTGSSREQAAT +LA+ + LV++GSFGNIFSRNSINNALLTLEIP
Sbjct: 554 SKTGAGDIIVSGFNFGTGSSREQAATCILARDMQLVIAGSFGNIFSRNSINNALLTLEIP 613

Query: 619 ALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQE 678
           ALI KLR++Y+G P ELTRRTGWF  WDV  A V VT+G  +GPVIL+QKVGELG+NLQE
Sbjct: 614 ALINKLRKRYEGQPAELTRRTGWFATWDVPAATVTVTDGK-NGPVILKQKVGELGQNLQE 672

Query: 679 IIVKGGLEGWVKSQL 693
           IIVKGGLEGWVK+QL
Sbjct: 673 IIVKGGLEGWVKAQL 687
>gi|110810414|sp|Q2HZ33|LYS4_CANPA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|86370932|gb|ABC94604.1| homoaconitase [Candida parapsilosis]
          Length = 688

 Score =  926 bits (2392), Expect = 0.0,   Method: Composition-based stats.
 Identities = 466/685 (68%), Positives = 538/685 (78%), Gaps = 29/685 (4%)

Query: 20  GQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPS 79
           GQNLTEKIVQ YAVNLP  K+VH+GDYV+IKPAHCMSHDNSWPVA KFMGLGA ++K+  
Sbjct: 18  GQNLTEKIVQKYAVNLPPNKLVHTGDYVTIKPAHCMSHDNSWPVATKFMGLGAKRVKDNR 77

Query: 80  QIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTV 139
           QIV TLDHD+QNK+EKNL KY NIE FAK+  ID YPAGRGIGHQIMIEEGYAFPLN+TV
Sbjct: 78  QIVCTLDHDVQNKTEKNLAKYANIERFAKEQGIDFYPAGRGIGHQIMIEEGYAFPLNLTV 137

Query: 140 ASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIV 199
           ASDSHSNTYGG+GSLGTPIVRTDAA+IWAT QTWWQIPPVA+VELKG L  GV+GKDIIV
Sbjct: 138 ASDSHSNTYGGVGSLGTPIVRTDAASIWATVQTWWQIPPVAKVELKGNLQNGVTGKDIIV 197

Query: 200 ALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKN 259
           ALCG+FNND+VLNHAIEF GD +  LPID+RLTIANMTTEWGALSGLFP+D  LI++Y+ 
Sbjct: 198 ALCGVFNNDEVLNHAIEFVGDGVENLPIDYRLTIANMTTEWGALSGLFPIDDKLIEFYEG 257

Query: 260 RLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVS 319
           RLQKLG  NHPRIN  TI AL   +    +D+DA YAK L+IDL TL+ YVSGPNSVKVS
Sbjct: 258 RLQKLGP-NHPRINKDTIEALRRGSL--ASDEDAKYAKHLVIDLNTLSPYVSGPNSVKVS 314

Query: 320 NTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAAS 379
           N +  LSQ +I INKAYLVSCTNSRLSD+Q+AADV+       K +KV P VEFYVAAAS
Sbjct: 315 NPLSKLSQDNIAINKAYLVSCTNSRLSDIQAAADVL-------KGHKVHPNVEFYVAAAS 367

Query: 380 SEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSK 439
           S ++ DA  +GAW+ ++ AG  PLP+GCGPCIGLG GLL+ GEVGISATNRNFKGRMGSK
Sbjct: 368 SLVQQDAEAAGAWQTIIDAGAKPLPAGCGPCIGLGTGLLKDGEVGISATNRNFKGRMGSK 427

Query: 440 DXXXXXXXXXXXXXXXXXGKISSP-----------AEVLSTSEIPFSGVKTXXXXXXXXX 488
           D                 GKI +P            E++ + ++P S   T         
Sbjct: 428 DALAYLASPEVVAASAVLGKIGAPEEIDGKPVNASPEIVKSIDLPKSSGNT-----GATS 482

Query: 489 XXXXAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQV 548
               ++ +  + SVE+L GFP+   GEL+LC+ADNINTDGIYPGKYTYQDD+ +E+MA+V
Sbjct: 483 EEPISEDDTSEASVEVLPGFPKSIQGELILCNADNINTDGIYPGKYTYQDDISREQMAEV 542

Query: 549 CMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSI 608
           CMENYD EF+TK    DI++SG+NFGTGSSREQAAT +LA+G+ LVV+GSFGNIFSRNSI
Sbjct: 543 CMENYDPEFKTKTKSDDIIISGYNFGTGSSREQAATCILARGMKLVVAGSFGNIFSRNSI 602

Query: 609 NNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQK 668
           NNALLTLEIP LI+KLR KY G   ELT RTGWFLKWDV   K +VT   LDG VIL+QK
Sbjct: 603 NNALLTLEIPELIEKLRVKYDGV-NELTIRTGWFLKWDV--TKALVTVADLDGEVILQQK 659

Query: 669 VGELGKNLQEIIVKGGLEGWVKSQL 693
           VGELG NLQ+IIVKGGLEGWVKS+L
Sbjct: 660 VGELGTNLQDIIVKGGLEGWVKSEL 684
>gi|68477399|ref|XP_717326.1| homoaconitase [Candida albicans SC5314]
 gi|68477558|ref|XP_717250.1| homoaconitase [Candida albicans SC5314]
 gi|74586059|sp|Q5A644|LYS4_CANAL Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|46438953|gb|EAK98277.1| potential homoaconitase [Candida albicans SC5314]
 gi|46439031|gb|EAK98354.1| potential homoaconitase [Candida albicans SC5314]
          Length = 684

 Score =  924 bits (2387), Expect = 0.0,   Method: Composition-based stats.
 Identities = 460/678 (67%), Positives = 541/678 (79%), Gaps = 14/678 (2%)

Query: 18  LKGQNLTEKIVQSYAVNL-PEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIK 76
           L+GQNLTEKIVQ YAV L P  K V+SGDYV+IKPAHCMSHDNSWPVA KFM LGA+K+K
Sbjct: 15  LRGQNLTEKIVQKYAVGLQPSSKKVYSGDYVTIKPAHCMSHDNSWPVATKFMNLGASKVK 74

Query: 77  NPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLN 136
           +  QIV TLDHD+QNKSE+NLTKY NIE FAK   ID YPAGRGIGHQIMIEEGYAFPLN
Sbjct: 75  DNRQIVCTLDHDVQNKSEQNLTKYTNIEKFAKSQGIDFYPAGRGIGHQIMIEEGYAFPLN 134

Query: 137 MTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKD 196
           +TVASDSHSNTYGG+G+LGTPIVRTDAA+IWATGQTWWQIPPVA+VEL GQLP+GV+GKD
Sbjct: 135 LTVASDSHSNTYGGIGALGTPIVRTDAASIWATGQTWWQIPPVAKVELIGQLPKGVTGKD 194

Query: 197 IIVALCGLFNNDQVLNHAIEFTG-DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID 255
           IIVALCG+FNND+VLNHAIEF G D+++ LPID+RLTIANMTTEWGALSGLFPVD+TL++
Sbjct: 195 IIVALCGIFNNDEVLNHAIEFVGDDAISKLPIDYRLTIANMTTEWGALSGLFPVDETLVE 254

Query: 256 WYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNS 315
           +Y+NRL+KL   +HPRIN +TI  L        +D DA YAK L IDL++L+ Y+SGPNS
Sbjct: 255 FYQNRLKKLNKPDHPRINNQTIDQLINNKL--TSDNDAVYAKHLQIDLSSLSPYISGPNS 312

Query: 316 VKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYV 375
           VK+SN++ DLSQQ+I INKAYLVSCTNSRLSD+Q+AAD++       K +KV P VEFYV
Sbjct: 313 VKISNSLYDLSQQNIAINKAYLVSCTNSRLSDIQAAADII-------KGHKVNPNVEFYV 365

Query: 376 AAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGR 435
           AAASS ++ DA +SGAW+ +L AG  PLP+GCGPCIGLG GLL+ GEVGISATNRNFKGR
Sbjct: 366 AAASSLVQKDAEQSGAWQTILDAGAKPLPAGCGPCIGLGTGLLKDGEVGISATNRNFKGR 425

Query: 436 MGSKDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXXAQT 495
           MGSKD                 GKI  P E+          +               + +
Sbjct: 426 MGSKDALAYLASPEVVAASAVLGKIGGPEELNGEPVKQAPRIIKSIETESNSANEAESTS 485

Query: 496 EAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA 555
           E    S++IL GFP+   GEL+LC+ADNINTDGIYPGKYTYQDD+ KE+MA+VCMENYD+
Sbjct: 486 EEASGSIDILPGFPQSIEGELILCNADNINTDGIYPGKYTYQDDITKEQMAKVCMENYDS 545

Query: 556 EFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTL 615
           +F +K  PGDI++SG+NFGTGSSREQAAT +LA+G+ L+V+GSFGNIFSRNSINNALLTL
Sbjct: 546 QFYSKTKPGDIIISGYNFGTGSSREQAATCILARGMKLIVAGSFGNIFSRNSINNALLTL 605

Query: 616 EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKN 675
           EIP LI KLR++Y+G   ELT RTGWFLKWDV  A+V V +G  D  +IL QKVGELG N
Sbjct: 606 EIPDLINKLRQQYEGN-DELTIRTGWFLKWDVTKAQVTVVDG--DDNLILTQKVGELGTN 662

Query: 676 LQEIIVKGGLEGWVKSQL 693
           LQ+IIVKGGLEGWVKS+L
Sbjct: 663 LQDIIVKGGLEGWVKSEL 680
>gi|50424173|ref|XP_460673.1| hypothetical protein DEHA0F08019g [Debaryomyces hansenii CBS767]
 gi|74631471|sp|Q6BM98|LYS4_DEBHA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|49656342|emb|CAG89007.1| unnamed protein product [Debaryomyces hansenii CBS767]
          Length = 688

 Score =  914 bits (2361), Expect = 0.0,   Method: Composition-based stats.
 Identities = 454/675 (67%), Positives = 532/675 (78%), Gaps = 16/675 (2%)

Query: 19  KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNP 78
           +GQNLTEKIVQ YAV L + K V SGDYV+IKPAHCMSHDNSWPVA KFMGLGAT + + 
Sbjct: 28  RGQNLTEKIVQKYAVGLADDKKVFSGDYVTIKPAHCMSHDNSWPVATKFMGLGATNVHDN 87

Query: 79  SQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMT 138
            QIV TLDHD+QNKSEKNL KY NIENFAK+  ID YPAGRGIGHQIMIEEGYA+PLN+T
Sbjct: 88  RQIVCTLDHDVQNKSEKNLEKYHNIENFAKEQGIDFYPAGRGIGHQIMIEEGYAYPLNLT 147

Query: 139 VASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDII 198
           VASDSHSNTYGG+GSLGTPIVRTDAA+IWATGQTWWQIPPVA+VEL GQLP+G +GKDII
Sbjct: 148 VASDSHSNTYGGIGSLGTPIVRTDAASIWATGQTWWQIPPVAKVELVGQLPKGATGKDII 207

Query: 199 VALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           VALCG+FNND+VLNHAIEFTG+ +  L +D+RLTIANMTTEWGALSGLFPVD+TL+++Y 
Sbjct: 208 VALCGIFNNDEVLNHAIEFTGEGVKNLSVDYRLTIANMTTEWGALSGLFPVDETLVNFYD 267

Query: 259 NRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKV 318
            R++KL    HPR+N  T++ L E      +D DA YAK L++DL++L+ Y+SGPNSVKV
Sbjct: 268 ERVKKL-PQPHPRVNENTVKNLSENKV--NSDNDAVYAKHLVVDLSSLSPYISGPNSVKV 324

Query: 319 SNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAA 378
           S ++ DLS+Q+IKINKAYLVSCTNSRLSD+++AAD++       K +KVA GVEFYVAAA
Sbjct: 325 STSLHDLSKQNIKINKAYLVSCTNSRLSDIKAAADII-------KGHKVAEGVEFYVAAA 377

Query: 379 SSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGS 438
           SS ++ DA   GAW+ ++ AG  PLP+GCGPCIGLG GLLE GEVGISATNRNFKGRMGS
Sbjct: 378 SSNVQKDAEAIGAWQDIIDAGAKPLPAGCGPCIGLGTGLLEDGEVGISATNRNFKGRMGS 437

Query: 439 KDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXXAQTEAP 498
           KD                 GKI  P E+      P                      +A 
Sbjct: 438 KDALAYLASPEVVAASAVLGKIGGPEELQGN---PVPTNPEIVRSITSNESTETVDPDAS 494

Query: 499 KQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFR 558
             SV++L+GFP+   GEL+LCDADNINTDGIYPGKYTYQDD+P+ KMA+VCMENYD+EF+
Sbjct: 495 GSSVDVLDGFPQSIEGELILCDADNINTDGIYPGKYTYQDDIPRSKMAEVCMENYDSEFK 554

Query: 559 TKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIP 618
            K   GDI++SG+NFGTGSSREQAATA+LA+ + LVV+GSFGNIFSRNSINNALLTLEIP
Sbjct: 555 QKTKAGDIIISGYNFGTGSSREQAATAILARDMKLVVAGSFGNIFSRNSINNALLTLEIP 614

Query: 619 ALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQE 678
           ALI KLREKY     ELT RTGWFLKWDV   +V V++   +G +IL QKVGELG NLQ+
Sbjct: 615 ALINKLREKY-AQSNELTIRTGWFLKWDVTKNQVTVSDS--EGNLILTQKVGELGTNLQD 671

Query: 679 IIVKGGLEGWVKSQL 693
           IIVKGGLEGWVK+QL
Sbjct: 672 IIVKGGLEGWVKAQL 686
>gi|149234467|ref|XP_001523113.1| homoaconitase, mitochondrial precursor [Lodderomyces elongisporus
           NRRL YB-4239]
 gi|146453222|gb|EDK47478.1| homoaconitase, mitochondrial precursor [Lodderomyces elongisporus
           NRRL YB-4239]
          Length = 688

 Score =  898 bits (2320), Expect = 0.0,   Method: Composition-based stats.
 Identities = 452/681 (66%), Positives = 530/681 (77%), Gaps = 23/681 (3%)

Query: 19  KGQNLTEKIVQSYAVNLP------EGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGA 72
           +GQNLTEKIVQ +A+ LP      + K+VHSGDYV+IKP HCMSHDNSWPVA KFMGLGA
Sbjct: 20  QGQNLTEKIVQRFAI-LPATADGSQQKLVHSGDYVTIKPQHCMSHDNSWPVATKFMGLGA 78

Query: 73  TKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYA 132
            K+K+  QIV TLDHD+QNKSE NL KY+NI  FAK   ID YPAGRGIGHQIMIEEGYA
Sbjct: 79  KKVKDNRQIVNTLDHDVQNKSEANLKKYENIAKFAKLQGIDFYPAGRGIGHQIMIEEGYA 138

Query: 133 FPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGV 192
           FP N+TVASDSHSNTYGG+ SLGTPIVRTDAA+IWATGQTWWQIPPVA+VELKG+L +GV
Sbjct: 139 FPGNLTVASDSHSNTYGGVASLGTPIVRTDAASIWATGQTWWQIPPVAKVELKGKLAKGV 198

Query: 193 SGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKT 252
           +GKDIIVALCG+FNND+VLNHAIEF GD +  L ID+RLTIANMTTEWGALSGLFPVD  
Sbjct: 199 TGKDIIVALCGVFNNDEVLNHAIEFVGDGVEQLSIDYRLTIANMTTEWGALSGLFPVDDK 258

Query: 253 LIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSG 312
           L+ WY+ RL+++G  +HPRIN KT+  L +     K+D DA YAK L+IDL+TL  YVSG
Sbjct: 259 LVQWYQQRLERVGP-DHPRINKKTVGELMQNQI--KSDADAKYAKHLVIDLSTLAPYVSG 315

Query: 313 PNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVE 372
           PNSVK+SN++  LSQ +I INKAYLVSCTNSRLSD+++AA ++       K +KV P VE
Sbjct: 316 PNSVKISNSLTKLSQDNIAINKAYLVSCTNSRLSDIEAAAGIL-------KGHKVHPNVE 368

Query: 373 FYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNF 432
           FYVAAASS ++ DA   GAW+ +L AG  PLP+GCGPCIGLG+GLL+ GEVGISATNRNF
Sbjct: 369 FYVAAASSLVQKDAEALGAWQTILDAGAKPLPAGCGPCIGLGSGLLKDGEVGISATNRNF 428

Query: 433 KGRMGSKDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXX 492
           KGRMGSKD                 G+I +P EV      P +                 
Sbjct: 429 KGRMGSKDALAYLASPEVVAASAILGRIGAPEEV---DGAPVNASPEIVKSIEIEDSLAP 485

Query: 493 AQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMEN 552
           A  +A   ++++LEGFP+   GEL+LC+ADNINTDGIYPGKYTYQDD+ KE+MA+VCMEN
Sbjct: 486 AADDASSGAIDVLEGFPKSIEGELILCNADNINTDGIYPGKYTYQDDISKEQMAEVCMEN 545

Query: 553 YDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNAL 612
           YD EF+TK    DI++SG+NFGTGSSREQAAT +LA+G+ LVV+GSFGNIFSRN+INNAL
Sbjct: 546 YDPEFKTKTRSDDIIISGYNFGTGSSREQAATCILARGMKLVVAGSFGNIFSRNAINNAL 605

Query: 613 LTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGEL 672
           LTLEIP LI KLREKYQG+  ELT RTGWFLKWDV  A V V +   D  VIL+QKVGEL
Sbjct: 606 LTLEIPDLINKLREKYQGS-NELTIRTGWFLKWDVTTATVTVADS--DANVILKQKVGEL 662

Query: 673 GKNLQEIIVKGGLEGWVKSQL 693
           G NLQ+IIVKGGLEGWVK++L
Sbjct: 663 GTNLQDIIVKGGLEGWVKAEL 683
>gi|45185124|ref|NP_982841.1| ABL106Cp [Ashbya gossypii ATCC 10895]
 gi|74695536|sp|Q75DX9|LYS4_ASHGO Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|44980760|gb|AAS50665.1| ABL106Cp [Ashbya gossypii ATCC 10895]
          Length = 686

 Score =  868 bits (2244), Expect = 0.0,   Method: Composition-based stats.
 Identities = 435/676 (64%), Positives = 519/676 (76%), Gaps = 9/676 (1%)

Query: 18  LKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKN 77
           + GQN TEKIVQ++AV L  G  V SGDYVSI+PAHCMSHDNSWPVALKFMGLGAT++ +
Sbjct: 16  VSGQNTTEKIVQAHAVGLRPGHRVASGDYVSIRPAHCMSHDNSWPVALKFMGLGATRVHD 75

Query: 78  PSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNM 137
             Q+V TLDHD+QN+SEKNL KY+NIE FA +  +D YPA RGIGHQIM+EEGYAFPL +
Sbjct: 76  ARQVVCTLDHDVQNRSEKNLAKYRNIELFAAQQGVDFYPARRGIGHQIMVEEGYAFPLGL 135

Query: 138 TVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDI 197
           TVASDSHSNTYGG+G+LGTP+VRTDAAAIWATGQTWWQ+PPVA+VEL G+LP GVSGKD 
Sbjct: 136 TVASDSHSNTYGGVGALGTPVVRTDAAAIWATGQTWWQVPPVARVELTGELPAGVSGKDA 195

Query: 198 IVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWY 257
           IVALCG+F  D+VLNHA+EF G  +  L ++ RLT+ANMTTEWGALSGLFPVD  L+DWY
Sbjct: 196 IVALCGVFGRDEVLNHAVEFAGPGVARLTVEQRLTVANMTTEWGALSGLFPVDGVLLDWY 255

Query: 258 KNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
           + ++ +     H R+    + AL E+A   + D DA YAK+L +DL++LTHYVSGPNSVK
Sbjct: 256 REQVAR-APAGHARLTAARVDALAERAAAMQPDTDARYAKQLTLDLSSLTHYVSGPNSVK 314

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAA 377
           V+  + +L+ Q ++I+KAYL+SCTN RL DL++AA V+   G+   V +VAPGVEFY+AA
Sbjct: 315 VARPIAELAPQQLRIDKAYLLSCTNGRLEDLEAAAAVLRADGN---VRQVAPGVEFYIAA 371

Query: 378 ASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMG 437
           AS+E+EA AR  G W+ LL AGCIPLPSGCGPCIGLG GLLE GEVGISATNRNF+GRMG
Sbjct: 372 ASAEVEAQARARGTWDVLLSAGCIPLPSGCGPCIGLGKGLLEAGEVGISATNRNFRGRMG 431

Query: 438 SKDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXXAQTEA 497
           SKD                 G+I++P EVL  S      V+              A  + 
Sbjct: 432 SKDAEAYLASPAVVAASAVLGRIAAPCEVLGLSPPAAPAVRA-----SVAQCGAPAAADG 486

Query: 498 PKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEF 557
              +VE+L GFPR  +GELVLCDADNINTDGIYPGKYTY+DD+P+E MA+VCMENYD +F
Sbjct: 487 AAAAVEVLPGFPRAITGELVLCDADNINTDGIYPGKYTYEDDIPRETMARVCMENYDLDF 546

Query: 558 RTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEI 617
           +  VH GDIVV G+NFGTGSSREQAATALLAKG+ LVV+GSF N FSRN+INNALLTLE+
Sbjct: 547 QHNVHAGDIVVGGYNFGTGSSREQAATALLAKGVPLVVAGSFSNTFSRNAINNALLTLEL 606

Query: 618 PALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQ 677
           PAL++ LRE+Y  AP + TRRTG FL WDVA A V VT GS  G  +L Q+VGE   NLQ
Sbjct: 607 PALLQLLRERYADAPSQATRRTGVFLTWDVAAATVTVTVGSPTGERVLHQRVGEFSANLQ 666

Query: 678 EIIVKGGLEGWVKSQL 693
           EIIVKGGLEGWVK  L
Sbjct: 667 EIIVKGGLEGWVKHAL 682
>gi|19114349|ref|NP_593437.1| homoaconitate hydratase Lys2 [Schizosaccharomyces pombe 972h-]
 gi|74638891|sp|Q9UT74|LYS4_SCHPO Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|5706517|emb|CAB52279.1| homoaconitate hydratase Lys2 [Schizosaccharomyces pombe]
          Length = 721

 Score =  811 bits (2094), Expect = 0.0,   Method: Composition-based stats.
 Identities = 416/673 (61%), Positives = 501/673 (74%), Gaps = 16/673 (2%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q +TEKIVQ +A N+PE K V SGDYV+IKP HCMSHDNSWPVALKFMG+GA K+ +  Q
Sbjct: 61  QTITEKIVQKFAQNIPENKYVRSGDYVTIKPKHCMSHDNSWPVALKFMGIGAKKVFDNRQ 120

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKSE NL KYKNIE+FAK   ID YPAGRGIGHQIM+E+GYA P +M VA
Sbjct: 121 IVCTLDHDVQNKSEANLRKYKNIESFAKGQGIDFYPAGRGIGHQIMVEQGYAMPGSMAVA 180

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSNTYGG+G LGTPIVRTDAAAIWATGQTWWQIPP+A+V L GQLP+G+SGKDIIV+
Sbjct: 181 SDSHSNTYGGVGCLGTPIVRTDAAAIWATGQTWWQIPPIARVNLVGQLPKGLSGKDIIVS 240

Query: 201 LCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNR 260
           LCG FN+D+VLNHAIEF G+ LN+L I+ RLTIANMTTEWGALSGLFP D+ L+ WY++R
Sbjct: 241 LCGAFNHDEVLNHAIEFYGEGLNSLSIESRLTIANMTTEWGALSGLFPTDEKLLAWYEDR 300

Query: 261 LQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVSN 320
           L+ LG  NHPR+N +T+ A+  KA    AD+ A YAK LI+DL+TL+  VSGPNSVKV N
Sbjct: 301 LKFLGP-NHPRVNRETLDAI--KASPILADEGAFYAKHLILDLSTLSPAVSGPNSVKVYN 357

Query: 321 TVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASS 380
           +   L ++DI I KAYLVSCTN RLSD+  AA+ V       K  KVA GVEFYV AASS
Sbjct: 358 SAATLEKKDILIKKAYLVSCTNGRLSDIHDAAETV-------KGKKVADGVEFYVGAASS 410

Query: 381 EIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKD 440
           E+EA A+K+G W+ L+ +G   LP+GCGPCIGLG GLL+ GEVGISATNRNFKGRMGS++
Sbjct: 411 EVEAAAQKNGDWQTLIDSGARTLPAGCGPCIGLGTGLLKDGEVGISATNRNFKGRMGSRE 470

Query: 441 XXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIPFSGVKTXXXXXXXXXXXXXAQTEAPKQ 500
                            GKI +P E    +    S V               + TEA   
Sbjct: 471 ALAYLASPAVVAASAIAGKIVAP-EGFKNAVSLVSAVDI--TDKVNKQTASKSSTEAVDS 527

Query: 501 SVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTK 560
              I++GFP   +GE+V CDADN+NTDGIYPG+YTY+DD+ KE+MA+VCMENYD+EF  K
Sbjct: 528 ETAIIDGFPSIVAGEIVFCDADNLNTDGIYPGRYTYRDDITKEEMAKVCMENYDSEFGKK 587

Query: 561 VHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPAL 620
               DI+VSGFNFGTGSSREQAATA+L++GI LVV GSF +IF RNSINNALL +++P L
Sbjct: 588 TKKDDILVSGFNFGTGSSREQAATAILSRGIPLVVGGSFSDIFKRNSINNALLAIQLPDL 647

Query: 621 IKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEII 680
           ++KLR  +    KELTRRTGW LKWDV  + V VT         +  K+GELG ++Q + 
Sbjct: 648 VQKLRTAFANESKELTRRTGWHLKWDVRKSTVTVTTSDNKE---MSWKIGELGNSVQSLF 704

Query: 681 VKGGLEGWVKSQL 693
           V+GGLEGWVK ++
Sbjct: 705 VRGGLEGWVKHEI 717
>gi|67540702|ref|XP_664125.1| LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate
           hydratase) [Aspergillus nidulans FGSC A4]
 gi|40738671|gb|EAA57861.1| LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate
           hydratase) [Aspergillus nidulans FGSC A4]
          Length = 776

 Score =  783 bits (2023), Expect = 0.0,   Method: Composition-based stats.
 Identities = 407/711 (57%), Positives = 494/711 (69%), Gaps = 40/711 (5%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ Y+V LP+GK V SGDYV+I+P  CM+HDNSWP ALKFM +GA+++ NP Q
Sbjct: 66  QTLTEKIVQKYSVGLPQGKFVKSGDYVTIQPHRCMTHDNSWPCALKFMSIGASRLHNPDQ 125

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKS+KNL KY+ IE FA +H ++ YPAGRGIGHQIMIEEG+A+P  + VA
Sbjct: 126 IVMTLDHDVQNKSDKNLKKYRQIEEFATQHGVEFYPAGRGIGHQIMIEEGFAWPGTLAVA 185

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTPIVRTDAA++WATG+TWWQIPPVA+V  KG LP GV+GKD+IVA
Sbjct: 186 SDSHSNMYGGVGCLGTPIVRTDAASVWATGKTWWQIPPVAKVTFKGVLPPGVTGKDVIVA 245

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLFN D VLNHAIEFTG  +++ +L +D RLTIANMTTEWGALSGLFP+D  L  W +
Sbjct: 246 LCGLFNKDDVLNHAIEFTGSEETMRSLSVDTRLTIANMTTEWGALSGLFPIDSVLKGWLR 305

Query: 259 NR--LQKLGTNNHPRINPKTIR----ALEEKAKIP-KADKDAHYAKKLIIDLATLTHYVS 311
            +     +G  + P       R     LE+  + P  ADK A YAK+L +DL++L+ YVS
Sbjct: 306 GKATTAAMGLADGPFKTRAAERFTHPLLEQLFENPLTADKGAKYAKELFLDLSSLSPYVS 365

Query: 312 GPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN--KVNKVAP 369
           GPNSVKV+  +++L  Q+IK++KAYLVSCTNSR SD+ +AA V     + N  K+ K+A 
Sbjct: 366 GPNSVKVATPLKELEAQNIKVDKAYLVSCTNSRASDIAAAAKVFKEAAEKNGGKIPKIAD 425

Query: 370 GVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATN 429
           GV+FY+AAAS   +  A  +G W+ LL+AG   LP+GCGPCIG+G GLLEPGEVGISA+N
Sbjct: 426 GVKFYIAAASIPEQLAAEGNGDWQTLLEAGATQLPAGCGPCIGMGQGLLEPGEVGISASN 485

Query: 430 RNFKGRMGSKDXXXXXXXXXXXXXXXXXGKISSPA-----------------------EV 466
           RNFKGRMGS +                 GK+S P                         +
Sbjct: 486 RNFKGRMGSTEAKAYLGSPEVVAASALSGKLSGPGWYQTPEGWTEVIRGEGDGIREEDRM 545

Query: 467 LSTSEIPFSGVKTXXXXXXXXXXXXXAQTEAPKQS----VEILEGFPREFSGELVLCDAD 522
           L+  E     +               ++T A ++S     EI  GFP   SGELV CDAD
Sbjct: 546 LTNEEALEKIIGQLDDLVADGEKRFASETPAVEESEQGLTEIYPGFPERVSGELVFCDAD 605

Query: 523 NINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQA 582
           N+NTDGIYPGKYTYQDDVP E MA+VCMENYD EF T    GDI+VSGFNFG GSSREQA
Sbjct: 606 NVNTDGIYPGKYTYQDDVPPETMARVCMENYDPEFSTTAKEGDILVSGFNFGCGSSREQA 665

Query: 583 ATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWF 642
           ATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P L+ +LRE +    K LTRRTGW 
Sbjct: 666 ATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLVNRLRETFGSGDKVLTRRTGWT 725

Query: 643 LKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           L WDV  +++ V EG   GP     KVGEL  N+QEII KGGLE WVK+ +
Sbjct: 726 LTWDVRKSQIEVQEGP-GGPK-WTHKVGELPPNVQEIIAKGGLEKWVKNAI 774
>gi|2492647|sp|Q92412|LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|1628374|emb|CAA67943.1| homoaconitase [Emericella nidulans]
          Length = 775

 Score =  777 bits (2007), Expect = 0.0,   Method: Composition-based stats.
 Identities = 406/711 (57%), Positives = 493/711 (69%), Gaps = 41/711 (5%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ Y+V LP+GK V SGDYV+I+P  CM+HDNSWP ALKFM +GA+++ NP Q
Sbjct: 66  QTLTEKIVQKYSVGLPQGKFVKSGDYVTIQPHRCMTHDNSWPCALKFMSIGASRLHNPDQ 125

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKS+KNL KY+ IE FA +H ++ YPAGRGIGHQIMIEEG+A+P  + VA
Sbjct: 126 IVMTLDHDVQNKSDKNLKKYRQIEEFATQHGVEFYPAGRGIGHQIMIEEGFAWPGTLAVA 185

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTPIVRTDAA++WATG+TWWQIPPVA+V  KG LP GV+GKD+IVA
Sbjct: 186 SDSHSNMYGGVGCLGTPIVRTDAASVWATGKTWWQIPPVAKVTFKGVLPPGVTGKDVIVA 245

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLFN D VLNHAIEFTG  +++ +L +D RLTIANMTTEWGALSGLFP+D  L  W +
Sbjct: 246 LCGLFNKDDVLNHAIEFTGSEETMRSLSVDTRLTIANMTTEWGALSGLFPIDSVLKGWLR 305

Query: 259 NR--LQKLGTNNHPRINPKTIR----ALEEKAKIP-KADKDAHYAKKLIIDLATLTHYVS 311
            +     +G  + P       R     LE+  + P  ADK A YAK+L +DL++L+ YVS
Sbjct: 306 GKATTAAMGLADGPFKTRAAERFTHPLLEQLFENPLTADKGAKYAKELFLDLSSLSPYVS 365

Query: 312 GPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN--KVNKVAP 369
           GPNSVKV+  +++L  Q+IK++KAYLVSCTNSR SD+ +AA V     + N  K+ K+  
Sbjct: 366 GPNSVKVATPLKELEAQNIKVDKAYLVSCTNSRASDIAAAAKVFKEAAEKNGGKIPKIH- 424

Query: 370 GVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATN 429
           GV+FY+AAAS   +  A  +G W+ LL+AG   LP+GCGPCIG+G GLLEPGEVGISA+N
Sbjct: 425 GVKFYIAAASIPEQLAAEGNGDWQTLLEAGATQLPAGCGPCIGMGQGLLEPGEVGISASN 484

Query: 430 RNFKGRMGSKDXXXXXXXXXXXXXXXXXGKISSPA-----------------------EV 466
           RNFKGRMGS +                 GK+S P                         +
Sbjct: 485 RNFKGRMGSTEAKAYLGSPEVVAASALSGKLSGPGWYQTPEGWTEVIRGEGDGIREEDRM 544

Query: 467 LSTSEIPFSGVKTXXXXXXXXXXXXXAQTEAPKQS----VEILEGFPREFSGELVLCDAD 522
           L+  E     +               ++T A ++S     EI  GFP   SGELV CDAD
Sbjct: 545 LTNEEALEKIIGQLDDLVADGEKRFASETPAVEESEQGLTEIYPGFPERVSGELVFCDAD 604

Query: 523 NINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQA 582
           N+NTDGIYPGKYTYQDDVP E MA+VCMENYD EF T    GDI+VSGFNFG GSSREQA
Sbjct: 605 NVNTDGIYPGKYTYQDDVPPETMARVCMENYDPEFSTTAKEGDILVSGFNFGCGSSREQA 664

Query: 583 ATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWF 642
           ATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P L+ +LRE +    K LTRRTGW 
Sbjct: 665 ATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLVNRLRETFGSGDKVLTRRTGWT 724

Query: 643 LKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           L WDV  +++ V EG   GP     KVGEL  N+QEII KGGLE WVK+ +
Sbjct: 725 LTWDVRKSQIEVQEGP-GGPK-WTHKVGELPPNVQEIIAKGGLEKWVKNAI 773
>gi|145602518|ref|XP_359935.2| hypothetical protein MGG_04842 [Magnaporthe grisea 70-15]
 gi|145010934|gb|EDJ95590.1| hypothetical protein MGG_04842 [Magnaporthe grisea 70-15]
          Length = 776

 Score =  776 bits (2004), Expect = 0.0,   Method: Composition-based stats.
 Identities = 404/714 (56%), Positives = 490/714 (68%), Gaps = 49/714 (6%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ Y+V L  GK V SGDYV++ P HCM+HDNSWPVALKFM +GA+KI +  Q
Sbjct: 69  QTLTEKIVQRYSVGLAPGKKVKSGDYVTLSPHHCMTHDNSWPVALKFMSIGASKIHDNRQ 128

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QNKSE NL KY+ IE FAK H +D YPAGRGIGHQIM+EEGYA+P  +TVA
Sbjct: 129 VVMTLDHDVQNKSESNLKKYRQIEEFAKTHGVDFYPAGRGIGHQIMVEEGYAWPGTVTVA 188

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V L G LP GV+GKD+IVA
Sbjct: 189 SDSHSNMYGGVGCLGTPMVRTDAASIWATGKTWWQIPPIAKVTLTGVLPPGVTGKDVIVA 248

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLFNND+VLNHAIEFTG  +++ ++P+D RL IANMTTEWGAL+GLFP+D  L  W +
Sbjct: 249 LCGLFNNDEVLNHAIEFTGSEETMRSIPVDDRLAIANMTTEWGALAGLFPIDSVLQGWLR 308

Query: 259 NRLQKLGTNNHPRINPKTIRALEEKAKIP-KADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
            +          R +  T   +EE  +   +AD  A YAK L ++L+TL  +V+GPNSVK
Sbjct: 309 GKATTSAMFGGGR-DVFTHEKIEELIQNQLRADPGAKYAKSLYLNLSTLAPFVAGPNSVK 367

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAA 377
           V+  ++DL  +DIK+NKAYLVSCTNSR SD+ +AA V        K   +APGV+FY+ A
Sbjct: 368 VATPLKDLEAKDIKVNKAYLVSCTNSRASDIAAAAKVFKEASKDGKPAVIAPGVKFYIGA 427

Query: 378 ASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMG 437
           AS+  +A A ++G W+ LL AG   LP+GCGPCIGLG GLLEPGEVGISA+NRNFKGRMG
Sbjct: 428 ASTLEQAAAEEAGDWKVLLDAGAQALPAGCGPCIGLGTGLLEPGEVGISASNRNFKGRMG 487

Query: 438 SKDXXXXXXXXXXXXXXXXXGKISSP---------------------------------A 464
           S D                 GKI+ P                                 A
Sbjct: 488 STDAKAYLASQEVVAASALKGKIAGPGWYEKPEGVEKVIIGEGNGDAVHDKAVSIEEALA 547

Query: 465 EVLSTSEIPFSGVKTXXXXXXXXXXXXXAQTEAPKQSVEILEGFPREFSGELVLCDADNI 524
           ++L  +E   S  +              A++   +   EIL GFP    GE+V CDADNI
Sbjct: 548 KLLGEAESMISDAE-----QNLGGSSQQAESAEEETLTEILPGFPERVEGEIVFCDADNI 602

Query: 525 NTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAAT 584
           NTDGIYPGKYTYQD+V  EKMA+VCMENYD EF      GD++V+GFNFG GSSREQAAT
Sbjct: 603 NTDGIYPGKYTYQDNVSTEKMAEVCMENYDKEFGKVAREGDVLVAGFNFGCGSSREQAAT 662

Query: 585 ALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAP-----KELTRRT 639
           A+LAK I LVV+GSFGNIFSRNSINNAL+ +E+P L+++LRE + G       K LTRRT
Sbjct: 663 AILAKRIPLVVAGSFGNIFSRNSINNALMGVEVPRLVERLRETFGGKEQGEENKALTRRT 722

Query: 640 GWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GW   WDV  +KV VTEGS  G     QKVGEL  N+QEII +GGLE WVKSQ+
Sbjct: 723 GWTFVWDVRRSKVTVTEGS--GGETWSQKVGELPPNVQEIIARGGLEKWVKSQI 774
>gi|85091303|ref|XP_958836.1| homoaconitase, mitochondrial precursor [Neurospora crassa OR74A]
 gi|74629440|sp|Q870W1|LYS4_NEUCR Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|28920223|gb|EAA29600.1| homoaconitase, mitochondrial precursor [Neurospora crassa OR74A]
 gi|28950383|emb|CAD71225.1| probable homoaconitase precursor [Neurospora crassa]
          Length = 784

 Score =  775 bits (2001), Expect = 0.0,   Method: Composition-based stats.
 Identities = 401/716 (56%), Positives = 493/716 (68%), Gaps = 51/716 (7%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ Y+V L  GK V SGDYV+++P HCM+HDNSWPVA+KFM +GA+KI +  Q
Sbjct: 75  QTLTEKIVQRYSVGLAPGKKVKSGDYVTLQPHHCMTHDNSWPVAMKFMSIGASKIHDNRQ 134

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QNKSE NL KY+ IE FA  H +D YPAGRGIGHQIM+EEGYA+P  +TVA
Sbjct: 135 VVMTLDHDVQNKSEANLKKYRQIEEFANTHGVDFYPAGRGIGHQIMVEEGYAWPGTVTVA 194

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V   G LP GV+GKD+IVA
Sbjct: 195 SDSHSNMYGGVGCLGTPMVRTDAASIWATGKTWWQIPPIAKVTFTGLLPPGVTGKDVIVA 254

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLFNND VLNHAIEFTG  +++ ++P+D RLTIANMTTEWGALSGLFP+D  L  W +
Sbjct: 255 LCGLFNNDDVLNHAIEFTGAEETMRSIPVDDRLTIANMTTEWGALSGLFPIDAVLASWMR 314

Query: 259 NRLQKLGTNNHPRINPKT------IRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSG 312
            +   +    HP +  K       I AL E   +  AD  A YAK+L ++L+TL+ +V+G
Sbjct: 315 AK-ATVTAMEHPELGDKAKFTHAKIDALLENPLV--ADPGATYAKQLYLNLSTLSPFVAG 371

Query: 313 PNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNK--VNKVAPG 370
           PNSVK++  ++DL  Q++K++KAYLVSCTNSR SD+ +AA V       N   + KVAPG
Sbjct: 372 PNSVKIATPLKDLEAQNLKLDKAYLVSCTNSRASDIAAAARVFKDAAADNNGVIPKVAPG 431

Query: 371 VEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNR 430
           V+FY+AAAS   +  A  SG W+ LL AG  PLPSGCGPCIGLG GLLEPGE+GISA+NR
Sbjct: 432 VKFYIAAASLLEQKQAEDSGDWQVLLDAGAEPLPSGCGPCIGLGTGLLEPGEIGISASNR 491

Query: 431 NFKGRMGSKDXXXXXXXXXXXXXXXXXGKISSPA-------------------------- 464
           NFKGRMGS D                 GKI+ P                           
Sbjct: 492 NFKGRMGSTDAKAYLASPEVVAASALKGKIAGPGWYQKPEGVEKVIIGEGNGVVEQDKAM 551

Query: 465 -------EVLSTSEIPFSGVKTXXXXXXXXXXXXXAQTEAPKQSVEILEGFPREFSGELV 517
                  ++++ +E   +  +              + +   +   EIL GFP   SGE++
Sbjct: 552 SIEDALDKIIAEAESLIANAEAGLTPESTSSSSSSSSSSEEESLTEILPGFPEAISGEII 611

Query: 518 LCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGS 577
            CDADNINTDGIYPGKYTYQD++   KMA+VCMENYDA F +    GDI+V+GFNFG GS
Sbjct: 612 FCDADNINTDGIYPGKYTYQDNITPAKMAEVCMENYDASFGSIARAGDILVTGFNFGCGS 671

Query: 578 SREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTR 637
           SREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ +E+P L+++LRE++    K  TR
Sbjct: 672 SREQAATAILAKQIPLVVSGSFGNIFSRNSINNALMGVEVPKLVQRLREEF--GDKVATR 729

Query: 638 RTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           RTGW L WDV  +KVVV E S       EQKVGEL  N+QEII +GGLE WVKSQ+
Sbjct: 730 RTGWKLTWDVRRSKVVVEEASGKK---WEQKVGELPPNVQEIIARGGLEKWVKSQI 782
>gi|119196529|ref|XP_001248868.1| hypothetical protein CIMG_02639 [Coccidioides immitis RS]
 gi|90307654|gb|EAS37285.1| hypothetical protein CIMG_02639 [Coccidioides immitis RS]
          Length = 801

 Score =  772 bits (1993), Expect = 0.0,   Method: Composition-based stats.
 Identities = 402/712 (56%), Positives = 494/712 (69%), Gaps = 43/712 (6%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ Y+V LP+ K V SGDYV+I P   M+HDNSWPVALKFM +GA+K+ +P+Q
Sbjct: 92  QTLTEKIVQRYSVGLPKDKYVKSGDYVTISPHRVMTHDNSWPVALKFMSIGASKLNDPNQ 151

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKSEKNL KY+ IE FAK H +D YPAGRGIGHQIM+EEGYA+P  + VA
Sbjct: 152 IVMTLDHDVQNKSEKNLKKYEQIETFAKTHGVDFYPAGRGIGHQIMVEEGYAWPGTLVVA 211

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V  +G LP+GV+GKD+IVA
Sbjct: 212 SDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVTFRGVLPKGVTGKDVIVA 271

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLF+ D VLNHAIEFTG  +++ ++ ID RLTIANMTTEWGALSGLFPVD  L  W +
Sbjct: 272 LCGLFDKDDVLNHAIEFTGSEETMRSIHIDDRLTIANMTTEWGALSGLFPVDSMLKGWLR 331

Query: 259 NR----------LQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           ++          + +L ++   R     +  L E+  +  ADK A YAK+L +DL+TL+ 
Sbjct: 332 SKATTAAMWGSTVPELQSSAAERFKHAALDQLFEEPLV--ADKGAKYAKELFLDLSTLSP 389

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN--KVNK 366
           YV+GPNSVKV+  +++L  Q+IK+NKAYLVSCTNSR SD+ +AA V     + N  K+ K
Sbjct: 390 YVAGPNSVKVATPLKELESQNIKVNKAYLVSCTNSRASDIAAAAKVFKEAAEKNGGKIPK 449

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           +A GV+FY+AAAS   +  A ++G W+ LL+AG  PLP+GCGPCIGLG GLLEPGEVGIS
Sbjct: 450 IADGVKFYIAAASIPEQRAAEEAGDWQALLEAGAEPLPAGCGPCIGLGTGLLEPGEVGIS 509

Query: 427 ATNRNFKGRMGSKDXXXXXXXXXXXXXXXXXGKISSP------------------AEVLS 468
           ATNRNFKGRMGS +                 G IS P                     + 
Sbjct: 510 ATNRNFKGRMGSTEAKAYLSSPEVVAASALSGTISGPGWYEKPEGWTGVVRGEGDGNEMI 569

Query: 469 TSEIPFSGVKTXXXXXXXXXXXXXAQTEAPKQS----VEILEGFPREFSGELVLCDADNI 524
           T+E     V               A  E+         E+  GFP   SGE+V CDADNI
Sbjct: 570 TAEQALEKVIGQLDSMVEDAEKLFASEESNSSGEEGLTEVYPGFPERVSGEIVFCDADNI 629

Query: 525 NTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAAT 584
           NTDGIYPGKYTYQD++P E+M + CMENYD +F      GDI+V+G+NFG GSSREQAAT
Sbjct: 630 NTDGIYPGKYTYQDNIPYEQMGEYCMENYDTQFGKVAKAGDILVTGYNFGCGSSREQAAT 689

Query: 585 ALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKY---QGAPKELTRRTGW 641
           A+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P LI +LRE +   +   K+LTRRTGW
Sbjct: 690 AILAKQIPLVVSGSFGNIFSRNSINNALMGLEVPRLITRLRETFGSDKTDSKQLTRRTGW 749

Query: 642 FLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            L WDV  +++ + EG  DGP    QKVGEL  N+QEII  GGLE WVK+ +
Sbjct: 750 TLTWDVRRSQIEIQEGP-DGPK-WTQKVGELPPNVQEIIALGGLEKWVKNSI 799
>gi|169596725|ref|XP_001791786.1| hypothetical protein SNOG_01131 [Phaeosphaeria nodorum SN15]
 gi|160707359|gb|EAT90780.2| hypothetical protein SNOG_01131 [Phaeosphaeria nodorum SN15]
          Length = 1654

 Score =  769 bits (1985), Expect = 0.0,   Method: Composition-based stats.
 Identities = 413/766 (53%), Positives = 495/766 (64%), Gaps = 101/766 (13%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ +AV + EGKV+ SGDYV+++P  CM+HDNSWPVALKFM +GAT+I +PSQ
Sbjct: 67  QTLTEKIVQRHAVGVAEGKVLRSGDYVTLQPHRCMTHDNSWPVALKFMSIGATRISDPSQ 126

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNK+EKNL KY  IE+FAKK  +  YPAGRGIGHQIM+EEGYA+P  + VA
Sbjct: 127 IVMTLDHDVQNKTEKNLKKYSQIEDFAKKQDVVFYPAGRGIGHQIMVEEGYAWPGTLAVA 186

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V L G +PQGV+GKD+IVA
Sbjct: 187 SDSHSNMYGGIGCLGTPVVRTDAASIWATGKTWWQIPPVAKVNLIGTMPQGVTGKDVIVA 246

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           L GLFN D+VLNHAIEFTG  +++ ++P+D RLTIANMTTEWGAL+GLFP+D  L  W +
Sbjct: 247 LAGLFNKDEVLNHAIEFTGTDETIGSIPVDDRLTIANMTTEWGALTGLFPIDSVLHGWLR 306

Query: 259 NR--LQKLGTNN----------HPRINP---KTIRALEEKAKIPK----ADKDAHYAKKL 299
            R  L  +G             H RI+     T    ++   I K    ADK A YAK+L
Sbjct: 307 ARATLAAMGEGQAKDHHQQQFVHERIDKLFTATGMVGKQLGHIFKPALAADKGAVYAKEL 366

Query: 300 IIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAA----DVV 355
            +DLATL+ YVSGPNSVKV+  + +L +Q+I INKAYLVSCTNSR SD+ +AA    D  
Sbjct: 367 FLDLATLSPYVSGPNSVKVATPLIELQEQNIPINKAYLVSCTNSRASDIAAAARVFKDAA 426

Query: 356 CPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGA 415
              GD  K+ K+A  V FY+AAAS   +  A ++G W+ LL+AG  PLP+GCGPCIGLG 
Sbjct: 427 VANGD--KIPKIADHVSFYIAAASIPEQKTAEEAGDWQTLLEAGAQPLPAGCGPCIGLGT 484

Query: 416 GLLEPGEVGISATNRNFKGRMGSKDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIP-- 473
           GLLEPGEVGISA+NRNFKGRMGS D                 G IS P       E P  
Sbjct: 485 GLLEPGEVGISASNRNFKGRMGSPDAKAYLASPEVVAASALSGSISGPGRY----EAPEG 540

Query: 474 FSGVK--------------------TXXXXXXXXXXXXXAQTEAPKQS------------ 501
           + GV+                                    TE+  QS            
Sbjct: 541 YEGVRRGEGDGILEENRMMTIEDMLEKAIKDAEAAIGSFGATESETQSAHPSAASGAEVE 600

Query: 502 --VEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRT 559
              EIL GFP +  GE+V CDADNINTDGIYPGKYTYQDDV +EKMA+VCMENYD  F  
Sbjct: 601 TLTEILPGFPEKIHGEIVFCDADNINTDGIYPGKYTYQDDVTREKMAEVCMENYDVGFGQ 660

Query: 560 KVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPA 619
               GDI+VSGFNFG GSSREQAATA+LAKGI LVV+GSFGNIFSRNSINNAL+ +E+P 
Sbjct: 661 TAKAGDILVSGFNFGCGSSREQAATAILAKGIPLVVAGSFGNIFSRNSINNALMGVEVPR 720

Query: 620 LIKKLREKYQGA--------------------------------PKELTRRTGWFLKWDV 647
           L  +LRE +  A                                 K+LTRRTGW L+WD+
Sbjct: 721 LTNRLREVFSSANTASSQQAIKEPSQNRESLDSPPPAATSQPAESKQLTRRTGWTLEWDI 780

Query: 648 ADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
             + V V EG          +VGEL  N+QEII  GGLE WVK ++
Sbjct: 781 RRSTVTVQEGPNGDK--WNVRVGELPPNVQEIIALGGLENWVKKEI 824
>gi|169776939|ref|XP_001822935.1| [Aspergillus oryzae]
 gi|110810413|sp|Q2U9G3|LYS4_ASPOR Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|83771672|dbj|BAE61802.1| unnamed protein product [Aspergillus oryzae]
          Length = 775

 Score =  768 bits (1983), Expect = 0.0,   Method: Composition-based stats.
 Identities = 411/712 (57%), Positives = 492/712 (69%), Gaps = 41/712 (5%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ Y+V L + K V SGDYV+I P  CM+HDNSWPVALKFM +GATK+ +P Q
Sbjct: 64  QTLTEKIVQKYSVGLAKDKFVKSGDYVTISPHRCMTHDNSWPVALKFMSIGATKLHDPKQ 123

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKSEKNL KY+ IE+FAK   ++ YPAGRGIGHQ+M+EEGYA+P  + VA
Sbjct: 124 IVMTLDHDVQNKSEKNLQKYRQIEDFAKHQGVEFYPAGRGIGHQVMVEEGYAWPGTLVVA 183

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTPIVRTD A+IWATG+TWWQIPPVA+V L G LP GV+GKD+IVA
Sbjct: 184 SDSHSNMYGGVGCLGTPIVRTDGASIWATGKTWWQIPPVAKVTLTGVLPPGVTGKDVIVA 243

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLF+ D VLNHAIEFTG  +++ +L +D RLTIANMTTEWGALSGLFP+D  L  W K
Sbjct: 244 LCGLFDKDDVLNHAIEFTGPEETMRSLSVDARLTIANMTTEWGALSGLFPIDNVLKGWLK 303

Query: 259 NR--LQKLGTNNHP--RINPK--TIRALEEKAKIP-KADKDAHYAKKLIIDLATLTHYVS 311
            +     +G    P   + P+  T   LE+    P  ADK A YAK+L +DL+TL+ YVS
Sbjct: 304 GKATTAAMGLAEGPFKTLAPQHFTHPLLEQLFANPLTADKGAKYAKELFLDLSTLSPYVS 363

Query: 312 GPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN--KVNKVAP 369
           GPNSVKV+  ++DL  Q+IK+NKAYLVSCTNSR SD+ +AA V     + N  KV K+A 
Sbjct: 364 GPNSVKVATPLKDLEAQNIKVNKAYLVSCTNSRASDIAAAARVFKEAAEKNGGKVPKIAD 423

Query: 370 GVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATN 429
           GVEFYVAAAS   +  A ++G W+ LL AG  PL  GC  CIGLG GLLE GEVGISA+N
Sbjct: 424 GVEFYVAAASIPEQLAAEEAGDWQALLDAGATPLLPGCAQCIGLGTGLLEAGEVGISASN 483

Query: 430 RNFKGRMGSKDXXXXXXXXXXXXXXXXXGKISSPA----------------------EVL 467
           RNFKGRMGS D                 GK+S P                       + +
Sbjct: 484 RNFKGRMGSTDAKAYLGSPEVVAASALTGKLSGPGWYQAPEGLTEVVRGEGDGIREEDRM 543

Query: 468 STSEIPFSGVKTXXXXXXXXXXXXXAQTEAPKQS----VEILEGFPREFSGELVLCDADN 523
            T+E     +               A  E+ + S     E+  GFP   SGE+V CDADN
Sbjct: 544 LTAEQALEKLIGQIDNLVADGEKQFAPEESEESSGDSLTEVYPGFPERVSGEIVFCDADN 603

Query: 524 INTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAA 583
           INTDGIYPGKYTYQDDV +E MAQVCM NYDA+F +    GDI+V+GFNFG GSSREQAA
Sbjct: 604 INTDGIYPGKYTYQDDVSQETMAQVCMSNYDAQFSSIAKEGDILVTGFNFGCGSSREQAA 663

Query: 584 TALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKY--QGAPKELTRRTGW 641
           TA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P LI +LRE +  +G+ K LTRRTGW
Sbjct: 664 TAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLINRLRESFSGEGSDKSLTRRTGW 723

Query: 642 FLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            L WDV  +++ V EG  +GP    Q VGEL  N+QEII KGGLE WVK+++
Sbjct: 724 TLTWDVRRSRIEVQEGE-NGPKWTHQ-VGELPPNVQEIIAKGGLEKWVKNEI 773
>gi|145250121|ref|XP_001396574.1| hypothetical protein An15g00350 [Aspergillus niger]
 gi|74584000|sp|Q58FL6|LYS4_ASPNG Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gi|61696870|gb|AAX53108.1| homoaconitate hydratase [Aspergillus niger]
 gi|134082087|emb|CAK42204.1| unnamed protein product [Aspergillus niger]
          Length = 769

 Score =  764 bits (1974), Expect = 0.0,   Method: Composition-based stats.
 Identities = 404/716 (56%), Positives = 493/716 (68%), Gaps = 54/716 (7%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ YAV LP+GK V SGDYV+I P   M+HDNSWPVALKFM +GA+K+ +P+Q
Sbjct: 63  QTLTEKIVQKYAVGLPDGKFVKSGDYVTIAPHRIMTHDNSWPVALKFMSIGASKMHDPNQ 122

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QNK+EKNL KY+ IE FAK+H ++ YPAGRGIGHQIM+EEG+A+P  + VA
Sbjct: 123 VVMTLDHDVQNKTEKNLQKYRQIEEFAKQHGVEFYPAGRGIGHQIMVEEGFAWPGTLVVA 182

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSNTYG + S+GTPIVRTDAA+IWATG+TWWQIPPVA+V   G LP GV+GKD+IVA
Sbjct: 183 SDSHSNTYGAVASVGTPIVRTDAASIWATGKTWWQIPPVAKVTFTGILPPGVTGKDVIVA 242

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLF+ D VLNHAIEFTG  +++ +LP+D RLTIANMTTEWGALSGLFP+D  L  W K
Sbjct: 243 LCGLFDKDDVLNHAIEFTGSEETMRSLPMDSRLTIANMTTEWGALSGLFPMDGVLKGWLK 302

Query: 259 NR------------LQKLGTNN--HPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLA 304
            +             + L   N  HP I    +  L        ADK A YAK+L +DL+
Sbjct: 303 GKATTAAMGLADGPFKTLAARNFTHPAIEQLFVNPL-------TADKGAKYAKELFLDLS 355

Query: 305 TLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN-- 362
           TL+ YVSGPNSVK++  +++L  QDIK++KAYLVSCTNSR SD+ +AA V     + N  
Sbjct: 356 TLSPYVSGPNSVKIATPLKELEAQDIKVDKAYLVSCTNSRASDIAAAAKVFKDAAEKNGG 415

Query: 363 KVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGE 422
           KV K+A GV+FY+AAAS   +  A  +G W+ LL+AG   LP+GCGPCIGLG GLLEPGE
Sbjct: 416 KVPKIADGVKFYIAAASIPEQLAAEGAGDWQTLLEAGATALPAGCGPCIGLGTGLLEPGE 475

Query: 423 VGISATNRNFKGRMGSKDXXXXXXXXXXXXXXXXXGKISSPA---------EVLS----- 468
           VGISA+NRNFKGRMGS +                 GK+S P          EV+      
Sbjct: 476 VGISASNRNFKGRMGSTEAKAYLGSPEIVAASALSGKLSGPGWYQPPEGWTEVVRGEGDG 535

Query: 469 -TSEIPFSGVKTXXXXXXXXXXXXXAQTE---APKQSV-------EILEGFPREFSGELV 517
              E      +              A  E   AP++ V       E+  GFP   SGE+V
Sbjct: 536 IREEDRMLNTEQALEKLLGQLDDLVADGEKRFAPEEKVEEEGGLTEVYPGFPERVSGEIV 595

Query: 518 LCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGS 577
            CDADN+NTD IYPG +TYQD+VP EKMA+VCM NYD EF +    GDI+V G+NFG GS
Sbjct: 596 FCDADNLNTDAIYPGYWTYQDNVPVEKMAEVCMSNYDKEFASIAKEGDILVVGYNFGCGS 655

Query: 578 SREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTR 637
           SREQAATALLAK I LVVSGSFGNIFSRNSINNAL+ LE+P L+ +LRE++    K+LTR
Sbjct: 656 SREQAATALLAKQIPLVVSGSFGNIFSRNSINNALMGLEVPRLVSRLREEF--GDKQLTR 713

Query: 638 RTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           RTGW L WDV  +++ + EG  +GP     KVGEL  N+QEII KGGLE WVK+ +
Sbjct: 714 RTGWTLTWDVRRSQIEIQEGQ-NGPK-WTHKVGELPPNVQEIIAKGGLEKWVKNAI 767
>gi|46138869|ref|XP_391125.1| hypothetical protein FG10949.1 [Gibberella zeae PH-1]
 gi|110810416|sp|Q4HVQ9|LYS4_GIBZE Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
          Length = 776

 Score =  763 bits (1971), Expect = 0.0,   Method: Composition-based stats.
 Identities = 394/710 (55%), Positives = 490/710 (69%), Gaps = 46/710 (6%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q L EKI Q YAV L  GK + +GDY+++ P HCMSHDN+WP+A KF+ +GA+KI N  Q
Sbjct: 74  QTLVEKIAQQYAVGLAPGKKIKAGDYIALAPHHCMSHDNTWPIAKKFLDIGASKIHNNRQ 133

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QNKSE NL KY  I  FA+KH + HYPAGRGIGHQIM+EEGYA+P  ++VA
Sbjct: 134 VVFTLDHDVQNKSEANLKKYSLIHEFAEKHGVIHYPAGRGIGHQIMVEEGYAWPGTVSVA 193

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGT +VRTDAA+IWATGQTWWQ+PPVA+V   G LP GV+GKD+I+A
Sbjct: 194 SDSHSNMYGGIGCLGTAVVRTDAASIWATGQTWWQVPPVAKVTFTGILPPGVTGKDVIIA 253

Query: 201 LCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNR 260
           LCGLF +DQVLNHA+EF G    +LPID RLTI+NMTTEWGAL+G+FPVD+ LI WY+ +
Sbjct: 254 LCGLFRDDQVLNHAVEFAGGE--SLPIDDRLTISNMTTEWGALAGVFPVDEMLISWYRGK 311

Query: 261 LQK---LGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
                  G ++  RIN K +  LE+     +AD +A YAK+L ++L+TL+  V+GPNSVK
Sbjct: 312 ATTNAMFGGSSKDRINHKRVDELEQNRL--EADPNAKYAKELYLNLSTLSPIVAGPNSVK 369

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAA 377
           ++  +++L  +DI +NKAYLVSCTNSR SD+ +AA V       NK  K+APGV FY+AA
Sbjct: 370 IATPLKNLEAEDIPVNKAYLVSCTNSRASDIAAAARVFREAAKENKDVKIAPGVNFYIAA 429

Query: 378 ASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMG 437
           AS   +  A ++G W+ L  AG   LP+GCGPCIGLG GLLEPGEVGISA+NRNFKGRMG
Sbjct: 430 ASLPEQEIAEEAGDWQVLRDAGAQVLPAGCGPCIGLGTGLLEPGEVGISASNRNFKGRMG 489

Query: 438 SKDXXXXXXXXXXXXXXXXXGKISSPA--------------------------------- 464
           S                   GKI+ P                                  
Sbjct: 490 STSAKAYLASPEIVAASALKGKIAGPGWYQKPEGVEKVIIGEGSGDYVADKALSIEDALD 549

Query: 465 EVLSTSEIPFSGVKTXXXXXXXXXXXXXAQTEAPKQSVEILEGFPREFSGELVLCDADNI 524
           ++++ ++   +  +T             A+ E  +   EIL GFP +  GE+V CD+DNI
Sbjct: 550 KLINEADALIAAAETSEGAKEQAASPTAAEGE--ESLTEILPGFPEKVEGEIVFCDSDNI 607

Query: 525 NTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAAT 584
           NTDGIYPGKYTYQD+V  EKMA+VCMENYD EF      GDI+V+GFNFG GSSREQAAT
Sbjct: 608 NTDGIYPGKYTYQDNVSVEKMAEVCMENYDTEFGKFAKAGDILVTGFNFGCGSSREQAAT 667

Query: 585 ALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQG-APKELTRRTGWFL 643
           ALLAK I LVVSGSFGNIFSRNSINNAL+ +E+P L+++LRE Y+    K LTRRTGW L
Sbjct: 668 ALLAKKIPLVVSGSFGNIFSRNSINNALMGVEVPRLVERLRETYKNDTEKPLTRRTGWKL 727

Query: 644 KWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            WDV  +KV+VTE   DG    EQKVGEL  N+QEII +GGLE WVK+++
Sbjct: 728 VWDVRRSKVIVTEK--DGSS-WEQKVGELPANVQEIIARGGLEKWVKAKI 774
>gi|166203450|gb|ABY84678.1| homoaconitase [Penicillium chrysogenum]
          Length = 785

 Score =  759 bits (1961), Expect = 0.0,   Method: Composition-based stats.
 Identities = 400/702 (56%), Positives = 483/702 (68%), Gaps = 36/702 (5%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ YAV LPEGK+V SGDY+S+ P +CM+HDNSWPVALKFM +GATKI  P Q
Sbjct: 87  QTLTEKIVQRYAVGLPEGKLVRSGDYISLAPGYCMTHDNSWPVALKFMSMGATKIHRPEQ 146

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QN S  NL KY+ IE FA +H ID YPAGRGIGHQ+M+EEGYA+P  M VA
Sbjct: 147 IVMTLDHDVQNTSAANLKKYEQIETFAGQHGIDFYPAGRGIGHQVMVEEGYAWPGTMAVA 206

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGT +VRTDAA+IWAT +TWWQIPPVA+V   G LP GV+GKD+IVA
Sbjct: 207 SDSHSNHYGGVGCLGTAVVRTDAASIWATSRTWWQIPPVARVTFTGTLPAGVTGKDVIVA 266

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDW-- 256
           LCGLFN+D VLNHAIEFTG  +++ +L +D RLTIANMTTEWGAL+GLFP+D+TL  W  
Sbjct: 267 LCGLFNSD-VLNHAIEFTGSEETMESLLVDSRLTIANMTTEWGALTGLFPIDRTLKRWLR 325

Query: 257 YKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSV 316
           YK     +  +   R      R  E  A    AD DA YAK+L ++L+TL+ YVSGPNSV
Sbjct: 326 YKATEAAMSEDRTTRQRITHERIDELFANPLTADPDAQYAKQLYLNLSTLSPYVSGPNSV 385

Query: 317 KVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN--KVNKVAPGVEFY 374
           KV+  + +L+QQ+IK+N+AY+VSCTNSR SDL +AA V       N     K+A GV+ Y
Sbjct: 386 KVATPLNELAQQNIKVNRAYIVSCTNSRASDLAAAAKVFKDAAKANPGTTPKIADGVKLY 445

Query: 375 VAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKG 434
           +AAAS+  +  A  +G W+ LL AG  PLP+GCGPCIGLG GLLEPGEVGISA+NRNFKG
Sbjct: 446 IAAASAPEQEAAESTGDWQALLDAGAQPLPAGCGPCIGLGTGLLEPGEVGISASNRNFKG 505

Query: 435 RMGSKDXXXXXXXXXXXXXXXXXGKISSPAEVLSTSEIP--FSGVK-------------- 478
           RMGS+D                 G IS P       ++P  +SGV+              
Sbjct: 506 RMGSRDALAYLASPEVVAASALSGVISGPG----AYQVPENWSGVEHGFGTGLPPTTENE 561

Query: 479 --TXXXXXXXXXXXXXAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTY 536
                           +  E  K + EIL GFP   SGE+V  DADN++TD IYPGK TY
Sbjct: 562 LTNLLQQMESLIDRVESAGEDSKPATEILPGFPERISGEIVFLDADNLDTDNIYPGKLTY 621

Query: 537 QDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVS 596
           QD+V K+ MA  CM+NYD EF+    P DI+V+GFNFG GSSREQAATA+LAK I LVV+
Sbjct: 622 QDNVSKDDMAAACMQNYDPEFKGIAKPSDILVAGFNFGCGSSREQAATAILAKQIPLVVA 681

Query: 597 GSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAP-----KELTRRTGWFLKWDVADAK 651
           GSFGNIFSRNSINNAL+ LE+P LI++LR  +   P     ++LTRRTGW L WDV  + 
Sbjct: 682 GSFGNIFSRNSINNALMGLEVPRLIERLRASFAQPPPGDAGRQLTRRTGWTLTWDVKRSV 741

Query: 652 VVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           V V EG   G    EQ VGEL  N+QEII +GGLE WVK ++
Sbjct: 742 VEVKEGE-SGESWTEQ-VGELPANVQEIIAEGGLEAWVKGKV 781