BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= YIR034C__[Saccharomyces_cerevisiae]
         (373 letters)

Database: nr.pal 
           6,348,806 sequences; 2,166,943,470 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|159795344|pdb|2QRJ|A  Chain A, Crystal Structure Of Sulfa...   727   0.0  
gi|6322225|ref|NP_012300.1|  Saccharopine dehydrogenase (NAD...   727   0.0  
gi|453184|emb|CAA54551.1|  saccharopine dehydrogenase (NAD+,...   725   0.0  
gi|160285837|pdb|2Q99|A  Chain A, Crystal Structure Of Sacch...   719   0.0  
gi|50287675|ref|XP_446267.1|  unnamed protein product [Candi...   593   e-168
gi|50308615|ref|XP_454310.1|  unnamed protein product [Kluyv...   566   e-159
gi|156839996|ref|XP_001643683.1|  hypothetical protein Kpol_...   562   e-158
gi|149234397|ref|XP_001523078.1|  saccharopine dehydrogenase...   535   e-150
gi|126273886|ref|XP_001387327.1|  Saccharopine dehydrogenase...   534   e-150
gi|50418933|ref|XP_457987.1|  hypothetical protein DEHA0C078...   532   e-149
gi|45185853|ref|NP_983569.1|  ACR167Cp [Ashbya gossypii ATCC...   518   e-145
gi|1170847|sp|P43065|LYS1_CANAL  Saccharopine dehydrogenase ...   511   e-143
gi|146412748|ref|XP_001482345.1|  hypothetical protein PGUG_...   501   e-140
gi|50546923|ref|XP_500931.1|  YlLYS5 [Yarrowia lipolytica] >...   468   e-130
gi|85116012|ref|XP_964977.1|  saccharopine dehydrogenase [Ne...   410   e-113
gi|156054636|ref|XP_001593244.1|  saccharopine dehydrogenase...   404   e-111
gi|154320959|ref|XP_001559795.1|  saccharopine dehydrogenase...   402   e-110
gi|19113884|ref|NP_592972.1|  saccharopine dehydrogenase [NA...   394   e-108
gi|39951433|ref|XP_363433.1|  hypothetical protein MGG_01359...   392   e-107
gi|115396504|ref|XP_001213891.1|  hypothetical protein ATEG_...   387   e-106
gi|116180468|ref|XP_001220083.1|  hypothetical protein CHGG_...   387   e-106
gi|70999462|ref|XP_754450.1|  saccharopine dehydrogenase Lys...   387   e-106
gi|119491548|ref|XP_001263295.1|  saccharopine dehydrogenase...   386   e-105
gi|145233023|ref|XP_001399884.1|  hypothetical protein An02g...   384   e-105
gi|169620241|ref|XP_001803532.1|  hypothetical protein SNOG_...   384   e-105
gi|121705814|ref|XP_001271170.1|  saccharopine dehydrogenase...   383   e-104
gi|68489408|ref|XP_711455.1|  saccharopine dehydrogenase [Ca...   382   e-104
gi|67524831|ref|XP_660477.1|  hypothetical protein AN2873.2 ...   377   e-103
gi|52783140|sp|Q870G1|LYS1_EMENI  Saccharopine dehydrogenase...   376   e-102
gi|119191478|ref|XP_001246345.1|  hypothetical protein CIMG_...   375   e-102
gi|169770813|ref|XP_001819876.1|  [Aspergillus oryzae] >gi|8...   373   e-101
gi|169844356|ref|XP_001828899.1|  hypothetical protein CC1G_...   365   2e-99
gi|58265844|ref|XP_570078.1|  saccharopine dehydrogenase (NA...   360   1e-97
gi|170084105|ref|XP_001873276.1|  predicted protein [Laccari...   350   1e-94
gi|154286608|ref|XP_001544099.1|  saccharopine dehydrogenase...   344   6e-93
gi|167522749|ref|XP_001745712.1|  predicted protein [Monosig...   328   3e-88
gi|71020369|ref|XP_760415.1|  hypothetical protein UM04268.1...   323   1e-86
gi|46138821|ref|XP_391101.1|  hypothetical protein FG10925.1...   312   2e-83
gi|164663315|ref|XP_001732779.1|  hypothetical protein MGL_0...   293   2e-77
gi|156386647|ref|XP_001634023.1|  predicted protein [Nematos...   278   5e-73
gi|83855180|ref|ZP_00948710.1|  saccharopine dehydrogenase (...   253   1e-65
gi|83941702|ref|ZP_00954164.1|  saccharopine dehydrogenase (...   252   4e-65
gi|54302781|ref|YP_132774.1|  hypothetical saccharopine dehy...   248   7e-64
gi|99079948|ref|YP_612102.1|  alanine dehydrogenase/PNT-like...   246   2e-63
gi|90411302|ref|ZP_01219314.1|  hypothetical saccharopine de...   246   2e-63
gi|149913155|ref|ZP_01901689.1|  saccharopine dehydrogenase,...   246   2e-63
gi|69935478|ref|ZP_00630414.1|  Alanine dehydrogenase/PNT, C...   243   2e-62
gi|86139349|ref|ZP_01057918.1|  saccharopine dehydrogenase, ...   241   8e-62
gi|126463509|ref|YP_001044623.1|  alanine dehydrogenase/PNT ...   238   4e-61
gi|77464669|ref|YP_354173.1|  saccharopine dehydrogenase (NA...   237   8e-61
gi|85703440|ref|ZP_01034544.1|  saccharopine dehydrogenase, ...   236   1e-60
gi|114769161|ref|ZP_01446787.1|  saccharopine dehydrogenase ...   236   2e-60
gi|84515065|ref|ZP_01002428.1|  saccharopine dehydrogenase (...   235   4e-60
gi|163736028|ref|ZP_02143453.1|  saccharopine dehydrogenase,...   233   2e-59
gi|149204190|ref|ZP_01881158.1|  saccharopine dehydrogenase,...   233   2e-59
gi|89067231|ref|ZP_01154744.1|  saccharopine dehydrogenase (...   232   3e-59
gi|146278974|ref|YP_001169133.1|  Saccharopine dehydrogenase...   232   4e-59
gi|163745490|ref|ZP_02152850.1|  saccharopine dehydrogenase,...   230   1e-58
gi|56698131|ref|YP_168503.1|  saccharopine dehydrogenase, pu...   229   2e-58
gi|83950968|ref|ZP_00959701.1|  saccharopine dehydrogenase, ...   228   4e-58
gi|89056506|ref|YP_511957.1|  Saccharopine dehydrogenase (NA...   228   8e-58
gi|126738269|ref|ZP_01753990.1|  saccharopine dehydrogenase,...   227   1e-57
gi|126736186|ref|ZP_01751929.1|  saccharopine dehydrogenase,...   226   2e-57
gi|110678073|ref|YP_681080.1|  saccharopine dehydrogenase, p...   226   2e-57
gi|163743615|ref|ZP_02150991.1|  saccharopine dehydrogenase,...   221   5e-56
gi|163739390|ref|ZP_02146801.1|  saccharopine dehydrogenase,...   219   2e-55
gi|126730845|ref|ZP_01746654.1|  saccharopine dehydrogenase,...   219   2e-55
gi|114763459|ref|ZP_01442866.1|  saccharopine dehydrogenase,...   217   9e-55
gi|126724841|ref|ZP_01740684.1|  saccharopine dehydrogenase,...   213   2e-53
gi|29828330|ref|NP_822964.1|  saccharopine dehydrogenase [St...   195   6e-48
gi|159036695|ref|YP_001535948.1|  alanine dehydrogenase/PNT ...   187   9e-46
gi|156386649|ref|XP_001634024.1|  predicted protein [Nematos...    86   4e-15
gi|88805943|ref|ZP_01121461.1|  hypothetical saccharopine de...    74   2e-11
gi|67941190|ref|ZP_00533414.1|  Alanine dehydrogenase/PNT, C...    72   5e-11
gi|126657261|ref|ZP_01728427.1|  hypothetical protein CY0110...    69   4e-10
gi|170028405|ref|XP_001842086.1|  alpha-aminoadipic semialde...    69   5e-10
gi|126646063|ref|ZP_01718580.1|  putative saccharopine dehyd...    65   8e-09
gi|115898561|ref|XP_797286.2|  PREDICTED: similar to sacchar...    64   2e-08
gi|125855220|ref|XP_684074.2|  PREDICTED: similar to lysine ...    64   2e-08
gi|157106746|ref|XP_001649464.1|  saccharopine dehydrogenase...    63   3e-08
gi|167521173|ref|XP_001744925.1|  predicted protein [Monosig...    60   3e-07
gi|158293377|ref|XP_314728.3|  AGAP008632-PA [Anopheles gamb...    60   3e-07
gi|118082239|ref|XP_416001.2|  PREDICTED: hypothetical prote...    60   3e-07
gi|53851170|gb|AAU95502.1|  lysine ketoglutarate reductase/s...    59   5e-07
gi|91092360|ref|XP_971717.1|  PREDICTED: similar to CG7144-P...    59   6e-07
gi|147903908|ref|NP_001085980.1|  MGC82978 protein [Xenopus ...    57   2e-06
gi|156548972|ref|XP_001607166.1|  PREDICTED: similar to ENSA...    56   4e-06
gi|157954073|ref|NP_001103267.1|  aminoadipate-semialdehyde ...    54   2e-05
gi|17541738|ref|NP_499884.1|  R02D3.1 [Caenorhabditis elegan...    52   1e-04
gi|23397395|ref|NP_609150.2|  CG7144 CG7144-PA [Drosophila m...    51   1e-04
gi|40215478|gb|AAR82744.1|  SD02276p [Drosophila melanogaster]     51   1e-04
gi|58332724|ref|NP_001011437.1|  hypothetical protein LOC496...    50   2e-04
gi|125985423|ref|XP_001356475.1|  GA20134-PA [Drosophila pse...    50   2e-04
gi|150024579|ref|YP_001295405.1|  Putative monofunctional ly...    49   5e-04
gi|157759497|ref|XP_001672092.1|  Hypothetical protein CBG13...    49   5e-04
gi|156376340|ref|XP_001630319.1|  predicted protein [Nematos...    49   5e-04
gi|91762071|ref|ZP_01264036.1|  alanine dehydrogenase [Candi...    49   6e-04
gi|156338729|ref|XP_001620022.1|  hypothetical protein NEMVE...    49   7e-04
gi|120436904|ref|YP_862590.1|  lysine 2-oxoglutarate reducta...    49   7e-04
gi|58258433|ref|XP_566629.1|  saccharopine dehydrogenase [Cr...    49   8e-04
>gi|159795344|pdb|2QRJ|A Chain A, Crystal Structure Of Sulfate-Bound Saccharopine
           Dehydrogenase (L-Lys Forming) From Saccharomyces
           Cerevisiae
 gi|159795345|pdb|2QRK|A Chain A, Crystal Structure Of Amp-Bound Saccharopine Dehydrogenase
           (L-Lys Forming) From Saccharomyces Cerevisiae
 gi|159795346|pdb|2QRL|A Chain A, Crystal Structure Of Oxalylglycine-Bound Saccharopine
           Dehydrogenase (L-Lys Forming) From Saccharomyces
           Cerevisiae
          Length = 394

 Score =  727 bits (1877), Expect = 0.0,   Method: Composition-based stats.
 Identities = 360/373 (96%), Positives = 360/373 (96%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 22  MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 81

Query: 61  AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
           AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 82  AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 141

Query: 121 LEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
           LEFLENDQGRRV             LGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 142 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 201

Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
           KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 202 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 261

Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
           PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 262 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 321

Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
           PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 322 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 381

Query: 361 DRHCARVKRSSRL 373
           DRHCARVKRSSRL
Sbjct: 382 DRHCARVKRSSRL 394
>gi|6322225|ref|NP_012300.1| Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the
           conversion of saccharopine to L-lysine, which is the
           final step in the lysine biosynthesis pathway; Lys1p
           [Saccharomyces cerevisiae]
 gi|82654956|sp|P38998|LYS1_YEAST Saccharopine dehydrogenase [NAD+, L-lysine-forming]
           (Lysine--2-oxoglutarate reductase) (SDH)
 gi|557840|emb|CAA86194.1| lys1 [Saccharomyces cerevisiae]
 gi|151943194|gb|EDN61529.1| lysine requiring protein [Saccharomyces cerevisiae YJM789]
          Length = 373

 Score =  727 bits (1876), Expect = 0.0,   Method: Composition-based stats.
 Identities = 360/373 (96%), Positives = 360/373 (96%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60

Query: 61  AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
           AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 61  AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120

Query: 121 LEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
           LEFLENDQGRRV             LGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180

Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
           KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240

Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
           PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300

Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
           PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360

Query: 361 DRHCARVKRSSRL 373
           DRHCARVKRSSRL
Sbjct: 361 DRHCARVKRSSRL 373
>gi|453184|emb|CAA54551.1| saccharopine dehydrogenase (NAD+, L-lysine forming) [Saccharomyces
           cerevisiae]
          Length = 373

 Score =  725 bits (1871), Expect = 0.0,   Method: Composition-based stats.
 Identities = 359/373 (96%), Positives = 359/373 (96%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60

Query: 61  AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
           AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 61  AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120

Query: 121 LEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
           LEFLENDQGRRV             LGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180

Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
           KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240

Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
           PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300

Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
           PTVLVPTT GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 301 PTVLVPTTVGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360

Query: 361 DRHCARVKRSSRL 373
           DRHCARVKRSSRL
Sbjct: 361 DRHCARVKRSSRL 373
>gi|160285837|pdb|2Q99|A Chain A, Crystal Structure Of Saccharopine Dehydrogenase From
           Saccharomyces Cerevisiae
          Length = 381

 Score =  719 bits (1855), Expect = 0.0,   Method: Composition-based stats.
 Identities = 357/373 (95%), Positives = 357/373 (95%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 9   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 68

Query: 61  AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
           AGSWKTAPRDRIIIGLKE PETDTFPLVHEHIQFAHCYKDQAGWQNVL RFIKGHGTLYD
Sbjct: 69  AGSWKTAPRDRIIIGLKEXPETDTFPLVHEHIQFAHCYKDQAGWQNVLXRFIKGHGTLYD 128

Query: 121 LEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
           LEFLENDQGRRV             LGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 129 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 188

Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
           KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 189 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 248

Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
           PQADIFINCIYLSKPIAPFTN EKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 249 PQADIFINCIYLSKPIAPFTNXEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 308

Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
           PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 309 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 368

Query: 361 DRHCARVKRSSRL 373
           DRHCARVKRSSRL
Sbjct: 369 DRHCARVKRSSRL 381
>gi|50287675|ref|XP_446267.1| unnamed protein product [Candida glabrata]
 gi|52783119|sp|Q6FU27|LYS1_CANGA Saccharopine dehydrogenase [NAD+, L-lysine-forming]
           (Lysine--2-oxoglutarate reductase) (SDH)
 gi|49525574|emb|CAG59191.1| unnamed protein product [Candida glabrata CBS 138]
          Length = 372

 Score =  593 bits (1529), Expect = e-168,   Method: Composition-based stats.
 Identities = 288/371 (77%), Positives = 316/371 (85%)

Query: 3   AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
           +VTLHLR ETKPLE RAALTPTTVK LI KGFKIYVE+SPQS F I+EYR+AGAIIVP G
Sbjct: 2   SVTLHLRGETKPLEHRAALTPTTVKHLIGKGFKIYVEESPQSIFKIDEYRRAGAIIVPFG 61

Query: 63  SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
           SW +APRDRIIIGLKEMPE D FPLVHEHIQFAHCYKDQAGW++VL RFI G+GTLYDLE
Sbjct: 62  SWISAPRDRIIIGLKEMPEEDKFPLVHEHIQFAHCYKDQAGWKDVLRRFINGNGTLYDLE 121

Query: 123 FLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
           FLE+D GRRV             LG+ DWAFKQTH D EDLPAVSPYPNEKAL+KD+ K 
Sbjct: 122 FLEDDNGRRVAAFGFYAGFAGAALGLADWAFKQTHKDSEDLPAVSPYPNEKALIKDIGKA 181

Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
           YK AL TGA+KP VLIIGALGRCGSGAID L KVG+P+ NI+KWDI+ETSRGGPF EI  
Sbjct: 182 YKNALKTGAKKPKVLIIGALGRCGSGAIDFLKKVGLPEENIIKWDIQETSRGGPFPEIAA 241

Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
           +DIFINCIYLSKPIAPF N E LN P+R+LRTVVDVSADTTNPHNPIPIY +ATVFNKPT
Sbjct: 242 SDIFINCIYLSKPIAPFINYELLNKPDRKLRTVVDVSADTTNPHNPIPIYNIATVFNKPT 301

Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
           V V T++GPKLSVISIDHLPSLLPREASEFF+HDLLPSLE LP R  +PVWVRA+KLF+R
Sbjct: 302 VKVNTSSGPKLSVISIDHLPSLLPREASEFFAHDLLPSLEQLPSRHVSPVWVRAEKLFNR 361

Query: 363 HCARVKRSSRL 373
           H AR  R S+L
Sbjct: 362 HSARAIRESKL 372
>gi|50308615|ref|XP_454310.1| unnamed protein product [Kluyveromyces lactis]
 gi|49643445|emb|CAG99397.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
          Length = 372

 Score =  566 bits (1458), Expect = e-159,   Method: Composition-based stats.
 Identities = 270/371 (72%), Positives = 309/371 (83%)

Query: 3   AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
           +VTLHLRAETKPLEAR ALTPTT KKL+ KGFKI+VE+S QS F+I EY++ GA IVP G
Sbjct: 2   SVTLHLRAETKPLEARTALTPTTTKKLLDKGFKIFVEESSQSAFDIEEYKKVGATIVPEG 61

Query: 63  SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
           SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYK+QAGW++VL RF +G+G LYDLE
Sbjct: 62  SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKNQAGWEDVLSRFKRGNGVLYDLE 121

Query: 123 FLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
           FLENDQGRRV             +G+RDWAFKQTHSD E+L A+ PY NE+A++KDV +D
Sbjct: 122 FLENDQGRRVAAFGFYAGFAGAAVGIRDWAFKQTHSDSENLGAIEPYENEEAMIKDVRRD 181

Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
           Y+ AL  GARKP VLIIGALGRCGSGA DLL K G+P+ NI+KWD+KET+RGGPF EI  
Sbjct: 182 YQLALKRGARKPKVLIIGALGRCGSGAADLLRKCGLPEENIIKWDMKETARGGPFQEIAD 241

Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
           AD+FINCIYLSKPI PF N E LN P RRLRTVVDVSADTTNPHNP+PIYT+ T F+ PT
Sbjct: 242 ADVFINCIYLSKPIPPFINNELLNKPTRRLRTVVDVSADTTNPHNPVPIYTINTTFDAPT 301

Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
           V VPTT GPKLSV SIDHLPSLLP+EASE FS DLLPSLE LPQR TA VWV+A+ L+++
Sbjct: 302 VQVPTTVGPKLSVCSIDHLPSLLPKEASESFSRDLLPSLEQLPQRATASVWVKARNLYEK 361

Query: 363 HCARVKRSSRL 373
             A+V R+S+L
Sbjct: 362 FAAKVGRTSKL 372
>gi|156839996|ref|XP_001643683.1| hypothetical protein Kpol_1057p13 [Vanderwaltozyma polyspora DSM
           70294]
 gi|156114304|gb|EDO15825.1| hypothetical protein Kpol_1057p13 [Vanderwaltozyma polyspora DSM
           70294]
          Length = 371

 Score =  562 bits (1448), Expect = e-158,   Method: Composition-based stats.
 Identities = 267/369 (72%), Positives = 303/369 (82%)

Query: 5   TLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSW 64
           TLHLRAETKPLEARAALTP+TVK LI KGFKIYVE+SPQS FN++EYR+ GA IVP GSW
Sbjct: 3   TLHLRAETKPLEARAALTPSTVKSLIKKGFKIYVEESPQSVFNVDEYRRCGATIVPFGSW 62

Query: 65  KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFL 124
            +APRDRIIIGLKEMPE D FPLVH+HIQFAHCYKDQ GW+ VL RFI G GTLYDLEFL
Sbjct: 63  ISAPRDRIIIGLKEMPEEDVFPLVHDHIQFAHCYKDQEGWEKVLRRFINGQGTLYDLEFL 122

Query: 125 ENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYK 184
           E+D G+RV             LG++DWAFK+TH D EDL A++PYPNEKAL++D++ +YK
Sbjct: 123 EDDNGKRVAAFGFYAGFAGAALGLKDWAFKKTHDDSEDLGALTPYPNEKALLRDISHEYK 182

Query: 185 EALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQAD 244
           +AL TGA+ P VLIIGALGRCGSGAID L K+GIP  NI+KWD++ET++GGPF EI   D
Sbjct: 183 QALKTGAKAPKVLIIGALGRCGSGAIDFLTKIGIPQENIIKWDMQETAKGGPFQEIVDTD 242

Query: 245 IFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPTVL 304
           IF+NCIYLSKPI PF NM  LN  +R L TVVDVSADTTNP+NPIPIY +ATVFNKPTV 
Sbjct: 243 IFVNCIYLSKPIPPFVNMSMLNQDSRHLTTVVDVSADTTNPYNPIPIYNIATVFNKPTVT 302

Query: 305 VPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDRHC 364
           VPT  GPKLSVISIDHLPSL+PREASE F+ DLLPSLELLP R  APVW RA  LF+RH 
Sbjct: 303 VPTKKGPKLSVISIDHLPSLMPREASEAFAKDLLPSLELLPNRHVAPVWTRAYSLFNRHS 362

Query: 365 ARVKRSSRL 373
           AR  RSS+L
Sbjct: 363 ARAYRSSKL 371
>gi|149234397|ref|XP_001523078.1| saccharopine dehydrogenase [Lodderomyces elongisporus NRRL YB-4239]
 gi|146453187|gb|EDK47443.1| saccharopine dehydrogenase [Lodderomyces elongisporus NRRL YB-4239]
          Length = 370

 Score =  535 bits (1378), Expect = e-150,   Method: Composition-based stats.
 Identities = 260/365 (71%), Positives = 293/365 (80%), Gaps = 1/365 (0%)

Query: 4   VTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGS 63
           V LHLRAETKPLEARAALTPTT K+L+  GFK+YVE+S QSTFN  EY   GA IVP GS
Sbjct: 6   VILHLRAETKPLEARAALTPTTTKQLLDAGFKVYVEESSQSTFNAKEYEAVGAEIVPEGS 65

Query: 64  WKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEF 123
           WK AP+DRII GLKE+PE DTFPLVH HIQFAHCYK+QAGW+ VL RF  G+GTLYDLEF
Sbjct: 66  WKDAPKDRIIFGLKELPENDTFPLVHTHIQFAHCYKNQAGWEKVLGRFPAGNGTLYDLEF 125

Query: 124 LENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDY 183
           LENDQGRRV             +GV DWAFKQ H DDE+LP VSPYPNE AL+KDV  + 
Sbjct: 126 LENDQGRRVAAFGFYAGFAGAAIGVLDWAFKQLHGDDENLPGVSPYPNEDALIKDVKTEL 185

Query: 184 KEALA-TGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
            +ALA  G + PT L+IGALGRCGSGAIDL  KVGIPD N+ KWD+ ET++GGPF EI  
Sbjct: 186 DKALAKNGGKYPTALVIGALGRCGSGAIDLFKKVGIPDDNVAKWDMAETAKGGPFKEIVD 245

Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
            +IF+NCIYLS+PIAPF N E LN P R+L T+VDVSADTTNPHNPIP+Y +ATVFN PT
Sbjct: 246 TNIFVNCIYLSQPIAPFINYETLNVPERKLTTIVDVSADTTNPHNPIPVYEIATVFNDPT 305

Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
           V V TTAGPKLSV SIDHLPSLLPREASEFFS DL+PSL  LP+R TAPVWVRAK+LFD+
Sbjct: 306 VPVKTTAGPKLSVCSIDHLPSLLPREASEFFSKDLMPSLLQLPERDTAPVWVRAKQLFDK 365

Query: 363 HCARV 367
           + AR+
Sbjct: 366 NVARL 370
>gi|126273886|ref|XP_001387327.1| Saccharopine dehydrogenase [NAD+, L-lysine-forming]
           (Lysine--2-oxoglutarate reductase) (SDH) [Pichia
           stipitis CBS 6054]
 gi|126213197|gb|EAZ63304.1| Saccharopine dehydrogenase [NAD+, L-lysine-forming]
           (Lysine--2-oxoglutarate reductase) (SDH) [Pichia
           stipitis CBS 6054]
          Length = 371

 Score =  534 bits (1375), Expect = e-150,   Method: Composition-based stats.
 Identities = 258/365 (70%), Positives = 294/365 (80%), Gaps = 1/365 (0%)

Query: 4   VTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGS 63
           V LHLRAETKPLE RAALTPTT K+LI  GFKI+VE S QSTF I EY QAGA IVP GS
Sbjct: 5   VILHLRAETKPLEHRAALTPTTTKQLIDAGFKIFVEKSSQSTFAIEEYEQAGATIVPEGS 64

Query: 64  WKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEF 123
           WK AP+DRIIIGLKE+PE +TFPLVHEHIQFAHCYKDQ GW++VL RF  G+GTLYDLEF
Sbjct: 65  WKEAPKDRIIIGLKELPEDETFPLVHEHIQFAHCYKDQGGWKDVLSRFPAGNGTLYDLEF 124

Query: 124 LENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDY 183
           LEND GRRV             +GVRDWAFKQ H D E+L  ++PYPNE  L+ DV KD 
Sbjct: 125 LENDTGRRVAAFGFYAGFAGAAIGVRDWAFKQLHPDSENLGGLTPYPNEDGLIADVKKDL 184

Query: 184 KEAL-ATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
           + AL   G + PT L+IGALGRCGSGAIDL  KVGIP+ NI KWDI+ET++GGPF EI +
Sbjct: 185 EAALQKNGGQYPTTLVIGALGRCGSGAIDLFRKVGIPEENITKWDIQETAKGGPFKEIVE 244

Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
           +DIF+NCIYLS+PI PF +   LN P+R+LR +VDVSADTTNPHNPIP+Y++ATVFN PT
Sbjct: 245 SDIFVNCIYLSQPIPPFIDYSSLNVPDRKLRIIVDVSADTTNPHNPIPVYSIATVFNDPT 304

Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
           V+V TTAGPKLSV SIDHLPSLLPREASEFFS DLLPSL  LP+R+TAPVW RAK LFD+
Sbjct: 305 VVVETTAGPKLSVCSIDHLPSLLPREASEFFSRDLLPSLLQLPERQTAPVWTRAKALFDK 364

Query: 363 HCARV 367
           H AR+
Sbjct: 365 HVARL 369
>gi|50418933|ref|XP_457987.1| hypothetical protein DEHA0C07832g [Debaryomyces hansenii CBS767]
 gi|49653653|emb|CAG86045.1| unnamed protein product [Debaryomyces hansenii CBS767]
          Length = 370

 Score =  532 bits (1371), Expect = e-149,   Method: Composition-based stats.
 Identities = 254/367 (69%), Positives = 296/367 (80%), Gaps = 1/367 (0%)

Query: 2   AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
           + VTLHLRAETKPLEARAALTP+T K+L+  GFK+YVE S QSTF+ +EY + GA IVP 
Sbjct: 3   SPVTLHLRAETKPLEARAALTPSTTKQLLDAGFKVYVEKSSQSTFDADEYEKVGATIVPE 62

Query: 62  GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
           GSWK AP+DRII GLKE+PE +TFPLVHEHIQFAHCYKDQ GW++VL RF +G GTLYDL
Sbjct: 63  GSWKEAPKDRIIFGLKELPEDETFPLVHEHIQFAHCYKDQGGWKDVLRRFPEGKGTLYDL 122

Query: 122 EFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
           EFLENDQGRRV             +GV DWAFKQTHSD+EDL  V+PYPNE  L+ DV K
Sbjct: 123 EFLENDQGRRVAAFGFYAGFAGAAIGVMDWAFKQTHSDNEDLRGVTPYPNEDELIADVKK 182

Query: 182 DYKEALA-TGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
              EAL   G   P  L+IGALGRCGSGA+D   KVGIPD  ++KWD+KET++GGPF EI
Sbjct: 183 VLDEALKKNGGEYPQCLVIGALGRCGSGALDFFKKVGIPDEKLIKWDMKETAKGGPFQEI 242

Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
            Q+DIF+NCIYLS+PI PF + E LN P+R+LRT+VDVSADTTNPHNPIP+Y++ATVFN 
Sbjct: 243 VQSDIFVNCIYLSQPIPPFIDYEGLNVPDRKLRTIVDVSADTTNPHNPIPVYSIATVFND 302

Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
           PTV V T+AGPKLSV SIDHLPSLLPREASEFF+ DL+PSL  LP R T+PVWVRAK+LF
Sbjct: 303 PTVPVETSAGPKLSVCSIDHLPSLLPREASEFFAKDLMPSLLELPNRDTSPVWVRAKQLF 362

Query: 361 DRHCARV 367
           D+H AR+
Sbjct: 363 DKHVARL 369
>gi|45185853|ref|NP_983569.1| ACR167Cp [Ashbya gossypii ATCC 10895]
 gi|52783132|sp|Q75BV4|LYS1_ASHGO Saccharopine dehydrogenase [NAD+, L-lysine-forming]
           (Lysine--2-oxoglutarate reductase) (SDH)
 gi|44981643|gb|AAS51393.1| ACR167Cp [Ashbya gossypii ATCC 10895]
          Length = 372

 Score =  518 bits (1334), Expect = e-145,   Method: Composition-based stats.
 Identities = 251/373 (67%), Positives = 303/373 (81%), Gaps = 1/373 (0%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           M+A+ LHLRAETKP+EARAALTPTTV+ L++ GFKIYVE+S QS F   EY  AGA +V 
Sbjct: 1   MSAI-LHLRAETKPMEARAALTPTTVRTLVSHGFKIYVEESAQSVFEAAEYAAAGAEVVA 59

Query: 61  AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
            GSW+ APR+RII+GLKE+PE DTFPL H HIQFAHCYK+Q+GW+ VL RF  G G LYD
Sbjct: 60  TGSWRGAPRERIIVGLKELPEEDTFPLEHTHIQFAHCYKNQSGWREVLGRFQSGGGLLYD 119

Query: 121 LEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
           LEFL++D+GRRV             LG+RDWA+KQTH+D EDLPAV+PY NE+ALV +V 
Sbjct: 120 LEFLQDDRGRRVAAFGYYAGFAGAALGLRDWAWKQTHTDAEDLPAVAPYENEQALVSEVA 179

Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
              +EA   GARKP VL+IGALGRCGSGA++LL + G+ D +I++WDI ET+RGGPF EI
Sbjct: 180 AACEEAYKKGARKPRVLVIGALGRCGSGAVELLRQCGLHDKHIIRWDIAETARGGPFPEI 239

Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
             ADIFINCIYLS+PIAPF NME L+ P+R+LRT+VDVSADTTNPHNP+P+Y VATVF+ 
Sbjct: 240 AAADIFINCIYLSQPIAPFINMELLDRPDRKLRTIVDVSADTTNPHNPVPVYNVATVFSS 299

Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
           PTV+VPT+ GPKLSVISIDHLPSLLPREASE F+ DLLPSL  LP+R TAPVW+RAK+LF
Sbjct: 300 PTVVVPTSQGPKLSVISIDHLPSLLPREASEAFASDLLPSLLQLPERDTAPVWLRAKELF 359

Query: 361 DRHCARVKRSSRL 373
            +HC R+ + +RL
Sbjct: 360 QQHCERLSKEARL 372
>gi|1170847|sp|P43065|LYS1_CANAL Saccharopine dehydrogenase [NAD+, L-lysine-forming]
           (Lysine--2-oxoglutarate reductase) (SDH)
 gi|536924|gb|AAA21362.1| saccharopine dehydrogenase
          Length = 382

 Score =  511 bits (1317), Expect = e-143,   Method: Composition-based stats.
 Identities = 249/378 (65%), Positives = 293/378 (77%), Gaps = 10/378 (2%)

Query: 2   AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
           + V LHLRAETKPLEARAALTP+T K+L+  GF+IYVE+S QSTF+I EY   GA IVP 
Sbjct: 4   SPVILHLRAETKPLEARAALTPSTTKQLLDAGFEIYVEESSQSTFDIKEYEAVGAKIVPE 63

Query: 62  GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
           GSWKTAP++RII GLKE+PE +TFPL+HEHIQFAHCYKDQAGWQ+VL RF +G+G LYDL
Sbjct: 64  GSWKTAPKERIIFGLKELPENETFPLIHEHIQFAHCYKDQAGWQDVLKRFPQGNGILYDL 123

Query: 122 EFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDED---------LPAVSPYPNE 172
           EFLENDQGRRV             +GV DW+FKQ + + +          LP V+PYPNE
Sbjct: 124 EFLENDQGRRVAAFGFYAGFAGAAIGVLDWSFKQLNGNTKGTKGEGEGGELPGVTPYPNE 183

Query: 173 KALVKDVTKDYKEALA-TGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKET 231
             L+KDV  + ++AL   G + P  L+IGALGRCGSGAIDL  K+GIPD NI KWD+ ET
Sbjct: 184 NELIKDVKIELEKALTKNGGQYPKCLVIGALGRCGSGAIDLFKKIGIPDDNIAKWDMAET 243

Query: 232 SRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPI 291
           ++GGPF EI  +DIFINCIYLSKPI PF N E LNN NR+L T+VDVSADTTNPHNPIP+
Sbjct: 244 AKGGPFQEIVDSDIFINCIYLSKPIPPFINKEILNNENRKLTTIVDVSADTTNPHNPIPV 303

Query: 292 YTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAP 351
           Y +ATVFN+PTV V    GPKLSV SIDHLPSLLPREASEFF+ DL+PSL  LP R T+P
Sbjct: 304 YEIATVFNEPTVEVKLDKGPKLSVCSIDHLPSLLPREASEFFAKDLMPSLLELPNRDTSP 363

Query: 352 VWVRAKKLFDRHCARVKR 369
           VWVRAK+LFD+H AR+ +
Sbjct: 364 VWVRAKQLFDKHVARLDK 381
>gi|146412748|ref|XP_001482345.1| hypothetical protein PGUG_05365 [Pichia guilliermondii ATCC 6260]
 gi|146393109|gb|EDK41267.1| hypothetical protein PGUG_05365 [Pichia guilliermondii ATCC 6260]
          Length = 370

 Score =  501 bits (1290), Expect = e-140,   Method: Composition-based stats.
 Identities = 241/367 (65%), Positives = 291/367 (79%), Gaps = 1/367 (0%)

Query: 2   AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
           A V+LHLRAETKPLEARA L+P+  K+L+  GFK+YVE S QSTF+ +EY + GA IVP 
Sbjct: 3   APVSLHLRAETKPLEARAGLSPSVTKELLDAGFKVYVEKSSQSTFDADEYAKVGAEIVPE 62

Query: 62  GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
           GSWK AP+DRII GLK +PE +TFPLVHEHIQFAHCYKDQAGW++VL RF  G+GTLYDL
Sbjct: 63  GSWKEAPKDRIIYGLKALPEDETFPLVHEHIQFAHCYKDQAGWKDVLSRFPAGNGTLYDL 122

Query: 122 EFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
           EFL ND+GRRV             +G++DWAFKQTH+D+E+L  V+PY  E+ L+KDV +
Sbjct: 123 EFLVNDEGRRVAAFGFYAGFAGAAIGLKDWAFKQTHADNEELRGVTPYATEEELIKDVKE 182

Query: 182 DYKEALA-TGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
           D   ALA  G + P  L+IGALGRCGSGA+ L  K GIPD  IL+WD+KET+RGGPF+EI
Sbjct: 183 DLDAALAKNGGKYPQCLVIGALGRCGSGAVSLFKKAGIPDEKILQWDMKETARGGPFEEI 242

Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
             +DIFINCIYLS+PI PF + E LN+  R+LRT+VDVSADTTNP+NPIP+YTV T F+K
Sbjct: 243 TDSDIFINCIYLSQPIPPFVSSETLNSEKRKLRTIVDVSADTTNPNNPIPVYTVITDFDK 302

Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
           PT LV TTAGPKLSV SIDHLPSL+PREASE F+ DLLP+L  LP R TAPV+ RAK+LF
Sbjct: 303 PTALVETTAGPKLSVCSIDHLPSLVPREASETFAKDLLPTLLQLPDRNTAPVYQRAKQLF 362

Query: 361 DRHCARV 367
           ++H AR+
Sbjct: 363 EKHVARL 369
>gi|50546923|ref|XP_500931.1| YlLYS5 [Yarrowia lipolytica]
 gi|729965|sp|P38997|LYS1_YARLI Saccharopine dehydrogenase [NAD+, L-lysine-forming]
           (Lysine--2-oxoglutarate reductase) (SDH)
 gi|173262|gb|AAA35248.1| saccharopine dehydrogenase
 gi|49646797|emb|CAG83182.1| YlLYS5 [Yarrowia lipolytica CLIB122]
          Length = 369

 Score =  468 bits (1204), Expect = e-130,   Method: Composition-based stats.
 Identities = 236/366 (64%), Positives = 277/366 (75%), Gaps = 1/366 (0%)

Query: 2   AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
           A V LHLRAETKPLE R+ALTPTT +KL+  GF+++VE SP   F+  E+   GA +V  
Sbjct: 3   APVKLHLRAETKPLEHRSALTPTTTRKLLDAGFEVFVEKSPLRIFDDQEFVDVGATLVEE 62

Query: 62  GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
           GSW +AP DR+IIGLKE+PE ++FPL HEHIQFAHCYKDQ GW++VL RF  G+GTLYDL
Sbjct: 63  GSWVSAPEDRMIIGLKELPE-ESFPLSHEHIQFAHCYKDQGGWKDVLSRFPAGNGTLYDL 121

Query: 122 EFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
           EFLE+D GRRV             +GV  WAF+QTH D E+LP VS YPNE  LV  + K
Sbjct: 122 EFLEDDNGRRVAAFGFHAGFAGAAIGVETWAFQQTHPDSENLPGVSAYPNETELVDKIKK 181

Query: 182 DYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIP 241
           D   A+  G++ PTVL+IGALGRCGSGAIDL  KVGIP+ NI++WD+ ET +GGPF EI 
Sbjct: 182 DLAAAVEKGSKLPTVLVIGALGRCGSGAIDLARKVGIPEENIIRWDMNETKKGGPFQEIA 241

Query: 242 QADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKP 301
            ADIFINCIYLS+PI PF N + LN   R+L  +VDVSADTTNPHNP+P+YT+AT F+ P
Sbjct: 242 DADIFINCIYLSQPIPPFINYDLLNKETRKLSVIVDVSADTTNPHNPVPVYTIATTFDHP 301

Query: 302 TVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFD 361
           TV V TTAGPKLSV SIDHLPSLLPREASE FS  LLPSL  LPQR TAPVW RAK LFD
Sbjct: 302 TVPVETTAGPKLSVCSIDHLPSLLPREASEAFSEALLPSLLQLPQRDTAPVWTRAKALFD 361

Query: 362 RHCARV 367
           +H  R+
Sbjct: 362 KHVLRI 367
>gi|85116012|ref|XP_964977.1| saccharopine dehydrogenase [Neurospora crassa OR74A]
 gi|52783134|sp|Q7SFX6|LYS1_NEUCR Saccharopine dehydrogenase [NAD+, L-lysine-forming]
           (Lysine--2-oxoglutarate reductase) (SDH)
 gi|28926776|gb|EAA35741.1| saccharopine dehydrogenase [Neurospora crassa OR74A]
          Length = 372

 Score =  410 bits (1055), Expect = e-113,   Method: Composition-based stats.
 Identities = 213/372 (57%), Positives = 257/372 (69%), Gaps = 4/372 (1%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           MA   LHLR+ETK LE R+ALTPTT  +LI  G+ + VE SP+  F+  E+ +AGA +VP
Sbjct: 1   MAPTVLHLRSETKHLEHRSALTPTTTAELIKAGYIVNVERSPERIFDDEEFEKAGATLVP 60

Query: 61  AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
             SW  AP++ II+GLKE+ E D FPL H H+QFAHCYK QAGW+NVL RF +G GTL D
Sbjct: 61  EHSWVDAPKEHIIVGLKELEEKD-FPLKHVHVQFAHCYKQQAGWENVLARFPRGGGTLLD 119

Query: 121 LEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
           LEFL ++ GRRV             L +  WA++  HS  E  P V  YPNE AL+ DV 
Sbjct: 120 LEFLVDEHGRRVAAFGFHAGFAGAALALEVWAWQLNHS--EPFPGVESYPNEDALIADVK 177

Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
           K  KE +    R P V++IGA GRCGSGA+  L K GIPD NIL WD+ ET++GGPF EI
Sbjct: 178 KAVKEGVEAAGRLPRVIVIGARGRCGSGAVSALKKAGIPDENILDWDMAETAKGGPFKEI 237

Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
             +DIF+NCIYL+  I  F NME L  P+R+LR V DVSADTT+P  P+PIYTVAT F+K
Sbjct: 238 TDSDIFVNCIYLTSKIPNFVNMESLQVPDRQLRVVCDVSADTTSPFTPVPIYTVATTFDK 297

Query: 301 PTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
           PTV V   T+GP LSVISIDHLPSLLPREASE FSHDLLPSL  L   + +PVW RAK+L
Sbjct: 298 PTVPVDGLTSGPPLSVISIDHLPSLLPREASEAFSHDLLPSLLTLNDWQNSPVWARAKQL 357

Query: 360 FDRHCARVKRSS 371
           FD   A +  S+
Sbjct: 358 FDEKVATLPESA 369
>gi|156054636|ref|XP_001593244.1| saccharopine dehydrogenase [Sclerotinia sclerotiorum 1980]
 gi|154703946|gb|EDO03685.1| saccharopine dehydrogenase [Sclerotinia sclerotiorum 1980]
          Length = 372

 Score =  404 bits (1039), Expect = e-111,   Method: Composition-based stats.
 Identities = 206/370 (55%), Positives = 253/370 (68%), Gaps = 2/370 (0%)

Query: 1   MAAVTLHLRAET-KPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIV 59
           M+  TLHLR+E  K LE R+ALTPTT K LI  G+ I VE SP+  F+  E+ + GA +V
Sbjct: 1   MSGTTLHLRSELGKALEHRSALTPTTAKALIDAGYTINVERSPERIFDDEEFEKVGATLV 60

Query: 60  PAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
           P  +W+ AP+D IIIGLKE+P  D FPL H H+QFAHCYK Q GW  VL RF +G GTL 
Sbjct: 61  PEDTWRQAPKDHIIIGLKELPVED-FPLEHVHVQFAHCYKQQGGWDTVLSRFPRGGGTLL 119

Query: 120 DLEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
           DLEFL +D+GRRV             L +  WA++ THS  E  P+VS YPNE  L+ DV
Sbjct: 120 DLEFLTDDKGRRVAAFGYHAGFAGAALALETWAWQLTHSASEPFPSVSSYPNEDELIADV 179

Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
            K          + P VL+IGALGRCGSGA+DL  + G+P  N+LKWD+ ET++GGPF E
Sbjct: 180 KKAIAAGQEKTGKAPRVLVIGALGRCGSGAVDLCLRAGVPTENVLKWDMAETAKGGPFPE 239

Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
           I ++DIFINCIYL   I  F +M+ L+ PNR+L  V DVSADTTNP+NPIPIYTVAT F+
Sbjct: 240 IVESDIFINCIYLMSKIPNFVDMQSLDTPNRKLSVVCDVSADTTNPNNPIPIYTVATTFS 299

Query: 300 KPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
           +PTV V     P+LSVISIDHLPSLLPREASE FS DLLPSL  L   ++ PVW +A+KL
Sbjct: 300 EPTVPVEVKGDPRLSVISIDHLPSLLPREASEAFSKDLLPSLLTLKDWRSTPVWAKAEKL 359

Query: 360 FDRHCARVKR 369
           F    A + +
Sbjct: 360 FQEKVATLPK 369
>gi|154320959|ref|XP_001559795.1| saccharopine dehydrogenase [Botryotinia fuckeliana B05.10]
 gi|150851892|gb|EDN27084.1| saccharopine dehydrogenase [Botryotinia fuckeliana B05.10]
          Length = 372

 Score =  402 bits (1032), Expect = e-110,   Method: Composition-based stats.
 Identities = 204/371 (54%), Positives = 253/371 (68%), Gaps = 2/371 (0%)

Query: 1   MAAVTLHLRAET-KPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIV 59
           M+  TLHLR+E  K LE R+ALTPTT K LI  G+ I VE SP+  F+  E+ + GA +V
Sbjct: 1   MSGTTLHLRSELGKALEHRSALTPTTAKALIDAGYTINVERSPERIFDDEEFEKVGATLV 60

Query: 60  PAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
           P  +W+ AP+D IIIGLKE+P  + FPL H H+QFAHCYK Q GW  VL RF +G GTL 
Sbjct: 61  PENTWRQAPKDHIIIGLKELP-VEEFPLEHVHVQFAHCYKQQGGWDTVLSRFPRGGGTLL 119

Query: 120 DLEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
           DLEFL +D+GRRV             L + +WA++ TH   E  P+VS YPNE  L+ DV
Sbjct: 120 DLEFLTDDRGRRVAAFGYHAGFAGAALALENWAWQLTHPASEPFPSVSSYPNEDELIVDV 179

Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
            K          + P VL+IGALGRCGSGA+DL  + G+P  N+LKWD+ ET++GGPF E
Sbjct: 180 KKAIAAGQEKTGKAPRVLVIGALGRCGSGAVDLCLRAGVPTENVLKWDMAETAKGGPFPE 239

Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
           I ++DIFINCIYL   I  F +M+ L+ PNR+L  V DVSADTTNP+NPIPIYTVAT F+
Sbjct: 240 IVESDIFINCIYLMSKIPNFVDMQSLDTPNRKLSVVCDVSADTTNPNNPIPIYTVATTFS 299

Query: 300 KPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
           +PTV V     P+LSVISIDHLPSLLPREASE FS DLLPSL  L   +  PVW +A+KL
Sbjct: 300 EPTVPVEVKGEPRLSVISIDHLPSLLPREASEAFSKDLLPSLLSLKDWRNTPVWAKAEKL 359

Query: 360 FDRHCARVKRS 370
           F    A + ++
Sbjct: 360 FQEKVATLPKN 370
>gi|19113884|ref|NP_592972.1| saccharopine dehydrogenase [NAD+, L-lysine forming] (PMID 3142867)
           [Schizosaccharomyces pombe 972h-]
 gi|12644398|sp|Q09694|LYS1_SCHPO Saccharopine dehydrogenase [NAD+, L-lysine-forming]
           (Lysine--2-oxoglutarate reductase) (SDH)
 gi|6455921|emb|CAB61467.1| saccharopine dehydrogenase [NAD+, L-lysine forming] (PMID 3142867)
           [Schizosaccharomyces pombe]
          Length = 368

 Score =  394 bits (1012), Expect = e-108,   Method: Composition-based stats.
 Identities = 203/363 (55%), Positives = 246/363 (67%), Gaps = 3/363 (0%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           M A  L LRAETKPLE R+ALTP T K L   GF+I +E S Q  F   E+ + G  +VP
Sbjct: 1   MVAPHLWLRAETKPLEERSALTPRTAKILADAGFQITIERSSQRAFKDKEFERLGFPMVP 60

Query: 61  AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
            GSW+ AP+D  IIGLKE+PE D  PL H HIQFAHCYK+Q GW+ VL RF  G+G LYD
Sbjct: 61  EGSWRHAPKDAYIIGLKELPENDNSPLKHTHIQFAHCYKNQEGWREVLSRFPAGNGLLYD 120

Query: 121 LEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
           LEFL++D GRRV             +    WA +  H + +  PA+ P+PNEK+LV+ V 
Sbjct: 121 LEFLQDDNGRRVAAFGYHAGFAGSAISCLVWAHQLLHPNKQ-FPAIRPFPNEKSLVRHVA 179

Query: 181 KDYKEALATGARK-PTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
           +  + AL     + P +L+IGALGRCG+GA DL  K+GIP  NIL+WDI ET +GGPF E
Sbjct: 180 RQVRLALKKNNNQYPRILVIGALGRCGTGACDLASKIGIPFDNILRWDINETKKGGPFTE 239

Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
           I ++DIF+NCIYLS PI  F  +E LN PNR+LR V DVS DTTNP+NPIPIY V T F+
Sbjct: 240 ITESDIFVNCIYLSMPIPKFCTVESLNVPNRKLRVVCDVSCDTTNPNNPIPIYNVNTTFD 299

Query: 300 KPTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKK 358
            PTV V   T  P L VISIDHLP+LLPRE+SE FS  L+PSL  L     APVWVRAKK
Sbjct: 300 HPTVEVKGVTTPPPLEVISIDHLPTLLPRESSEAFSEALIPSLLALKDVDNAPVWVRAKK 359

Query: 359 LFD 361
           L++
Sbjct: 360 LYE 362
>gi|39951433|ref|XP_363433.1| hypothetical protein MGG_01359 [Magnaporthe grisea 70-15]
 gi|145020817|gb|EDK04946.1| hypothetical protein MGG_01359 [Magnaporthe grisea 70-15]
          Length = 365

 Score =  392 bits (1006), Expect = e-107,   Method: Composition-based stats.
 Identities = 209/360 (58%), Positives = 251/360 (69%), Gaps = 12/360 (3%)

Query: 6   LHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWK 65
           LHLR+ETKPLE R+ALTPTT K LI  G+ + VE SP   F+  E+   GA +VP GSW+
Sbjct: 5   LHLRSETKPLEHRSALTPTTTKALIEAGYTVNVERSPVRIFDDAEFEAVGATLVPEGSWE 64

Query: 66  TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLE 125
             P+D I+IGLKE+ E D FPL H HIQFAHCYK+Q GW  VL R+  G G L D+EFLE
Sbjct: 65  QIPKDHIVIGLKELEEKD-FPLKHTHIQFAHCYKNQGGWDKVLRRYHDGEGMLLDIEFLE 123

Query: 126 NDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYKE 185
            D GRRV             L +++WA++ T+S  E LP+V   PNE ALV D+    KE
Sbjct: 124 KD-GRRVAAFGYWAGFAGAALALQNWAWQLTNSG-EPLPSVESRPNEAALVGDI----KE 177

Query: 186 ALATGARK----PTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIP 241
           ALA G  K    P V++IGALGRCG GA+D+  K GIPD NILKWD++ET+ GGPF EI 
Sbjct: 178 ALAGGKEKAGRLPRVIVIGALGRCGRGAVDMCKKAGIPDENILKWDMEETAPGGPFKEIV 237

Query: 242 QADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKP 301
           ++DIF+NCIYL+K I PF  ME LN P R+L  + D SADTTNP NP+P+YTVAT F+KP
Sbjct: 238 ESDIFVNCIYLNKQIPPFVTMESLNTPERKLSVINDCSADTTNPFNPVPVYTVATTFDKP 297

Query: 302 TVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
           TV V   + GP LSVISIDHLPSLLPREASE FS+DLLP L  L   K+ PVW  A+KLF
Sbjct: 298 TVPVDGLSHGPPLSVISIDHLPSLLPREASESFSNDLLPYLLKLKDWKSDPVWAGAEKLF 357
>gi|115396504|ref|XP_001213891.1| hypothetical protein ATEG_04713 [Aspergillus terreus NIH2624]
 gi|114193460|gb|EAU35160.1| hypothetical protein ATEG_04713 [Aspergillus terreus NIH2624]
          Length = 988

 Score =  387 bits (994), Expect = e-106,   Method: Composition-based stats.
 Identities = 204/377 (54%), Positives = 253/377 (67%), Gaps = 6/377 (1%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           M +  + LRAETKP EAR+ALTPTT K LI  G+ + VE S Q  F  +E+ + GA +V 
Sbjct: 612 MPSNKIWLRAETKPAEARSALTPTTAKALIDAGYDVTVERSKQRIFEDDEFPKIGAKLVE 671

Query: 61  AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
            GSW K AP+D  I+GLKE+PE D FPL H HI FAHCYK Q GW+ VL R+ +G GTL 
Sbjct: 672 EGSWVKDAPKDAFILGLKELPEDD-FPLEHVHISFAHCYKQQGGWEKVLSRWPRGGGTLL 730

Query: 120 DLEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
           DLEFL +D GRRV             L V++WA++ TH + E LP   PY N+  L++ V
Sbjct: 731 DLEFLTDDAGRRVAAFGYSAGYAGSALAVKNWAWQLTHPEGEPLPGEVPYANQDLLIQSV 790

Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
            +  +       R P VL+IGALGRCG GA+ L   VGIP+++I++WD++ET +GGPF E
Sbjct: 791 KESLEAGKKASGRSPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDMEETKKGGPFRE 850

Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
           I + ADIF+NCIYLS PI PF N E L++PNRRL  + DVSADTTNPHNPIP+YTV T F
Sbjct: 851 IIEDADIFVNCIYLSSPIPPFLNGETLSSPNRRLSVICDVSADTTNPHNPIPVYTVTTTF 910

Query: 299 NKPTV---LVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
           ++PTV   L   T GP LSVISIDHLPSLLPRE+SE FS  LLPSL  L   + A VW +
Sbjct: 911 DRPTVPVILPAGTQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDWQNARVWKQ 970

Query: 356 AKKLFDRHCARVKRSSR 372
           A+ LF    A +  S R
Sbjct: 971 AEDLFKEKVATLPESMR 987
>gi|116180468|ref|XP_001220083.1| hypothetical protein CHGG_00862 [Chaetomium globosum CBS 148.51]
 gi|88185159|gb|EAQ92627.1| hypothetical protein CHGG_00862 [Chaetomium globosum CBS 148.51]
          Length = 375

 Score =  387 bits (994), Expect = e-106,   Method: Composition-based stats.
 Identities = 204/375 (54%), Positives = 248/375 (66%), Gaps = 7/375 (1%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           MA   LHLR+ETKPLE R+ALTPTT   LI  G+ + VE SP   F+  E+  AGA +VP
Sbjct: 1   MAPTVLHLRSETKPLEHRSALTPTTTAALIKAGYTVNVERSPVRIFDDAEFEAAGATLVP 60

Query: 61  AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
             SW  AP++ IIIGLKE+ E + FPL H H+QFAHCYK Q GW+ VL RF +G GTL D
Sbjct: 61  EYSWVDAPKEHIIIGLKELEEKE-FPLKHVHVQFAHCYKQQGGWETVLARFPRGGGTLLD 119

Query: 121 LEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
           LEFL ++ GRRV             L +  W+++  HS  E  P V  YPNE ALV +V 
Sbjct: 120 LEFLVDENGRRVAAFGYHAGFAGAALALEVWSWQLNHS--EPFPGVESYPNEDALVSNVK 177

Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
           K     +    R P V++IGALGRCGSGA++ L K G+P+ NILKWD+ ET+ GGPF EI
Sbjct: 178 KALASGIEKAGRSPRVIVIGALGRCGSGAVEALRKAGVPEENILKWDMAETAGGGPFKEI 237

Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSA---DTTNPHNPIPIYTVATV 297
             +DIF+NCIYL+K I  F N+E L  P+R+L  V DVSA   DTT+P  P+PIYTVAT 
Sbjct: 238 TDSDIFVNCIYLTKKIPNFVNLESLQVPDRKLSVVCDVSAASQDTTSPFTPVPIYTVATT 297

Query: 298 FNKPTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRA 356
           F++PTV V    +GP LSVISIDHLPSLLPREASE FS DLLPSL  L   +  PVW RA
Sbjct: 298 FDEPTVAVEGLQSGPALSVISIDHLPSLLPREASEAFSQDLLPSLLALNDWQNTPVWSRA 357

Query: 357 KKLFDRHCARVKRSS 371
            KLF    A +  S+
Sbjct: 358 DKLFKEKVATLPASA 372
>gi|70999462|ref|XP_754450.1| saccharopine dehydrogenase Lys1 [Aspergillus fumigatus Af293]
 gi|66852087|gb|EAL92412.1| saccharopine dehydrogenase Lys1, putative [Aspergillus fumigatus
           Af293]
 gi|159127467|gb|EDP52582.1| saccharopine dehydrogenase Lys1, putative [Aspergillus fumigatus
           A1163]
          Length = 374

 Score =  387 bits (994), Expect = e-106,   Method: Composition-based stats.
 Identities = 203/377 (53%), Positives = 257/377 (68%), Gaps = 9/377 (2%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           M++  + LRAETKP EAR+ALTPTT K L+  G+++ VE S Q  F++    Q GA +V 
Sbjct: 1   MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSRQRIFDV---VQIGAPLVE 57

Query: 61  AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
            GSW K AP+D  I+GLKE+PE D FPL H HI FAHCYK QAGW+ VL R+ +G GTL 
Sbjct: 58  EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQAGWEKVLSRWPRGGGTLL 116

Query: 120 DLEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
           DLEFL ++ GRRV             L +++WA++ TH + E LP  +PY N+  L++ V
Sbjct: 117 DLEFLTDETGRRVAAFGYSAGYAGSALAIKNWAWQLTHPEGEPLPGETPYANQDLLIESV 176

Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
            +  +       R P VL+IGALGRCG GA+ L   VGIP+++I++WDI+ET +GGPF E
Sbjct: 177 KESLESGKKLSGRPPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDIEETKKGGPFRE 236

Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
           I + ADIFINCIYLS  I PF N E L++PNRRL  + DVSADTTNP+NPIP+Y++ T F
Sbjct: 237 IVEDADIFINCIYLSAKIPPFVNTETLSSPNRRLSVICDVSADTTNPNNPIPVYSITTTF 296

Query: 299 NKPTVLVP---TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
           +KPTV VP      GP LSVISIDHLPSLLPRE+SE FS  LLPSL  L  RK A VW +
Sbjct: 297 DKPTVTVPLPELAQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDRKNARVWKQ 356

Query: 356 AKKLFDRHCARVKRSSR 372
           A+ LF+   A +  S R
Sbjct: 357 AEDLFNEKVATLPESMR 373
>gi|119491548|ref|XP_001263295.1| saccharopine dehydrogenase Lys1, putative [Neosartorya fischeri
           NRRL 181]
 gi|119411455|gb|EAW21398.1| saccharopine dehydrogenase Lys1, putative [Neosartorya fischeri
           NRRL 181]
          Length = 374

 Score =  386 bits (992), Expect = e-105,   Method: Composition-based stats.
 Identities = 202/377 (53%), Positives = 257/377 (68%), Gaps = 9/377 (2%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           M++  + LRAETKP EAR+ALTPTT K L+  G+++ VE S Q  F++    Q GA +V 
Sbjct: 1   MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSTQRIFDV---VQIGAPLVE 57

Query: 61  AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
            GSW K AP+D  I+GLKE+PE D FPL H HI FAHCYK QAGW+ VL R+ +G GTL 
Sbjct: 58  EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQAGWEKVLSRWPRGGGTLL 116

Query: 120 DLEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
           DLEFL +D GRRV             L +++WA++ TH + E LP  +PY N+  L++ V
Sbjct: 117 DLEFLTDDTGRRVAAFGYSAGYAGSALAIKNWAWQLTHPEGEPLPGETPYANQDLLIESV 176

Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
            +  +       R P VL+IGALGRCG GA+ L   VGIP+++I++WD++ET +GGPF E
Sbjct: 177 KESLESGKKLSGRPPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDLEETKKGGPFRE 236

Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
           I + ADIFINCIYLS  I PF N E L++P RRL  + DVSADTTNP+NPIP+Y++ T F
Sbjct: 237 IVEDADIFINCIYLSAKIPPFVNTETLSSPKRRLSVICDVSADTTNPNNPIPVYSITTTF 296

Query: 299 NKPTVLVPTT---AGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
           +KPTV VP +    GP LSVISIDHLPSLLPRE+SE FS  LLPSL  L  RK A VW +
Sbjct: 297 DKPTVTVPLSERAQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDRKNARVWEQ 356

Query: 356 AKKLFDRHCARVKRSSR 372
           A+ LF+   A +  S R
Sbjct: 357 AEDLFNEKVATLPESIR 373
>gi|145233023|ref|XP_001399884.1| hypothetical protein An02g07500 [Aspergillus niger]
 gi|134056807|emb|CAK37714.1| unnamed protein product [Aspergillus niger]
          Length = 377

 Score =  384 bits (986), Expect = e-105,   Method: Composition-based stats.
 Identities = 198/377 (52%), Positives = 253/377 (67%), Gaps = 6/377 (1%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
           M++  + LRAETKP EAR+ALTPTT K L+  G+++ VE S Q  F+  ++ + GA +V 
Sbjct: 1   MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSTQRIFDDEDFAKIGAPLVE 60

Query: 61  AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
            GSW K AP+D  I+GLKE+PE D FPL H HI FAHCYK Q GW+ VL R+ +G GTL 
Sbjct: 61  EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQGGWEQVLSRWPRGGGTLL 119

Query: 120 DLEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
           DLEFL +D GRRV             L V++WA++ TH + E LP   PY N+ AL++ V
Sbjct: 120 DLEFLTDDVGRRVAAFGWSAGYAGSALAVKNWAWQLTHPEGEPLPGEVPYINQDALIESV 179

Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
            K  ++      R P +L+IGALGRCGSGA+ L   VGIPD++I++WDI+ET +GGPF E
Sbjct: 180 KKSLEDGKKQSGRSPKILVIGALGRCGSGAVQLAKDVGIPDSDIVRWDIEETKKGGPFRE 239

Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
           I +  DI +NCIYLS  I PF   E L +P RRL  + DVSADTTNPHNP+P+Y++ T F
Sbjct: 240 IVEDVDILVNCIYLSAQIPPFVTPETLTSPKRRLSVICDVSADTTNPHNPLPVYSITTTF 299

Query: 299 NKPTVLVPTTAGPK---LSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
           +KPTV V    G +   LSVISIDHLPSLLPRE+SE FS  LLPSL  L  R+ A VW +
Sbjct: 300 DKPTVPVTLAGGNQVAGLSVISIDHLPSLLPRESSEMFSQALLPSLLQLKDRQNARVWKQ 359

Query: 356 AKKLFDRHCARVKRSSR 372
           A+ LF+   A +  S R
Sbjct: 360 AEDLFNEKVATLPESLR 376
>gi|169620241|ref|XP_001803532.1| hypothetical protein SNOG_13323 [Phaeosphaeria nodorum SN15]
 gi|111058087|gb|EAT79207.1| hypothetical protein SNOG_13323 [Phaeosphaeria nodorum SN15]
          Length = 387

 Score =  384 bits (986), Expect = e-105,   Method: Composition-based stats.
 Identities = 203/374 (54%), Positives = 248/374 (66%), Gaps = 17/374 (4%)

Query: 1   MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQS-----TFNINEYRQAG 55
           M+  TLH RAE KPLE R+ALTPTT KKL+  G+ + VE SP+       F   E+ QAG
Sbjct: 1   MSFPTLHARAEAKPLEHRSALTPTTAKKLLDAGYPVLVERSPKDPNYARIFKDEEFEQAG 60

Query: 56  AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
           A ++  G++KTAP+DRIIIGLKE+PE D FPL H  + FAHCYK Q GW+ VL RF +G 
Sbjct: 61  ATLIEEGAYKTAPKDRIIIGLKELPE-DEFPLEHTFVHFAHCYKQQGGWEKVLARFPRGG 119

Query: 116 GTLYDLEFLENDQGRRVXXXXXXXXXXXXXLGVRDWAFKQTHSDDEDLPAVSP------- 168
           GTLYDLEFL++  GRRV             L ++ WA++ TH + E LP V         
Sbjct: 120 GTLYDLEFLQDTTGRRVAAFGYHAGFVGAALAIKTWAWQLTHPNGEPLPGVETFTDGRGY 179

Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
           Y NE  L+  + +D          KP+ L++GALGRCGSGA+DLL K+G P+  I KWD+
Sbjct: 180 YNNESELITQLKEDVAAGEKVAGHKPSSLVLGALGRCGSGAVDLLEKIGCPE--IKKWDL 237

Query: 229 KET-SRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHN 287
            ET  R GP+ EI ++DIF+NCIYLSKPI PF N E L +P R+L  V DVS DTTNPHN
Sbjct: 238 PETKERDGPYPEIIESDIFVNCIYLSKPIPPFVNKESLKSPKRKLSVVCDVSCDTTNPHN 297

Query: 288 PIPIYTVATVFNKPTVLVPTTA-GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQ 346
           PIPIY + T F+KPTV V     GP+LSVISIDHLPS LPRE+SE FS+ LLPSL  L  
Sbjct: 298 PIPIYDINTTFDKPTVGVDVEGDGPRLSVISIDHLPSALPRESSEAFSNALLPSLMALKD 357

Query: 347 RKTAPVWVRAKKLF 360
           R T PVW  A+KLF
Sbjct: 358 RATTPVWQGAEKLF 371