BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= AAB46420.1__[Trypanosoma_brucei]
(512 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
sp|P50098|IMDH_TRYBB Inosine-5'-monophosphate dehydrogenase... 1021 0.0
ref|XP_828081.1| inosine-5'-monophosphate dehydrogenase [Tr... 885 0.0
ref|XP_805772.1| inosine-5'-monophosphate dehydrogenase, pu... 870 0.0
ref|XP_815489.1| inosine-5'-monophosphate dehydrogenase, pu... 865 0.0
ref|XP_001465126.1| inosine-5'-monophosphate dehydrogenase ... 808 0.0
ref|XP_001682745.1| inosine-5'-monophosphate dehydrogenase ... 807 0.0
gb|AAR17482.1| inosine 5' monophosphate dehydrogenase [Leis... 807 0.0
ref|XP_001564275.1| inosine-5'-monophosphate dehydrogenase ... 804 0.0
emb|CAI21140.1| novel protein similar to vertebrate IMP (in... 561 e-158
emb|CAK04261.1| novel protein similar to vertebrate IMP (in... 557 e-157
ref|NP_001082410.1| similar to inosine 5'-phosphate dehydro... 556 e-156
ref|XP_001252299.1| PREDICTED: inosine monophosphate dehydr... 553 e-155
ref|NP_001002177.1| hypothetical protein LOC431724 [Danio r... 553 e-155
ref|NP_001014391.1| hypothetical protein LOC338306 [Danio r... 553 e-155
ref|NP_001025772.1| inosine monophosphate dehydrogenase 2 [... 552 e-155
ref|NP_001071309.1| inosine monophosphate dehydrogenase 1 [... 550 e-155
ref|NP_899066.1| inosine monophosphate dehydrogenase 1 isof... 549 e-154
ref|NP_001017283.1| IMP (inosine monophosphate) dehydrogena... 549 e-154
ref|NP_001096075.1| inosine monophosphate dehydrogenase 1 i... 548 e-154
sp|P20839|IMDH1_HUMAN Inosine-5'-monophosphate dehydrogenas... 548 e-154
ref|NP_000874.2| inosine monophosphate dehydrogenase 1 isof... 548 e-154
gb|EAW64946.1| hCG2002013, isoform CRA_a [Homo sapiens] 548 e-154
gb|AAA36112.1| inosine-5'-monophosphate dehydrogenase (EC 1... 548 e-154
ref|NP_001080792.1| inosine 5'-phosphate dehydrogenase 1 [X... 548 e-154
gb|EAW83652.1| IMP (inosine monophosphate) dehydrogenase 1,... 548 e-154
ref|XP_001110855.1| PREDICTED: inosine monophosphate dehydr... 548 e-154
ref|NP_000875.2| inosine monophosphate dehydrogenase 2 [Hom... 547 e-154
gb|EDL13789.1| inosine 5'-phosphate dehydrogenase 1, isofor... 547 e-154
emb|CAQ13978.1| IMP (inosine monophosphate) dehydrogenase 2... 546 e-153
ref|NP_035959.2| inosine 5'-phosphate dehydrogenase 1 [Mus ... 546 e-153
ref|XP_850933.1| PREDICTED: similar to inosine 5-phosphate ... 546 e-153
ref|NP_001008066.1| IMP (inosine monophosphate) dehydrogena... 546 e-153
gb|EDM15208.1| IMP (inosine monophosphate) dehydrogenase 1 ... 546 e-153
ref|XP_001494600.1| PREDICTED: similar to hCG2002013 [Equus... 546 e-153
ref|NP_001029588.1| IMP (inosine monophosphate) dehydrogena... 545 e-153
pdb|1JCN|A Chain A, Binary Complex Of Human Type-I Inosine ... 545 e-153
ref|NP_035960.2| inosine 5'-phosphate dehydrogenase 2 [Mus ... 545 e-153
ref|NP_001083990.1| inosine 5'-phosphate dehydrogenase 2 [X... 545 e-153
gb|AAA39311.1| IMP dehydrogenase (EC 1.2.1.14) 544 e-153
ref|XP_001478203.1| PREDICTED: similar to Inosine 5-phospha... 544 e-153
ref|NP_958872.1| inosine monophosphate dehydrogenase 2 [Dan... 544 e-153
ref|XP_001367707.1| PREDICTED: similar to hCG2002013, [Mono... 544 e-153
sp|P12269|IMDH2_CRIGR Inosine-5'-monophosphate dehydrogenas... 544 e-153
dbj|BAE25403.1| unnamed protein product [Mus musculus] 544 e-153
ref|XP_001372080.1| PREDICTED: similar to Inosine monophosp... 543 e-153
sp|P50096|IMDH1_MOUSE Inosine-5'-monophosphate dehydrogenas... 543 e-152
gb|EAW83649.1| IMP (inosine monophosphate) dehydrogenase 1,... 543 e-152
gb|AAA20181.1| IMP dehydrogenase 542 e-152
dbj|BAE30628.1| unnamed protein product [Mus musculus] 542 e-152
ref|XP_001641875.1| predicted protein [Nematostella vectens... 541 e-152
ref|XP_862835.1| PREDICTED: similar to Inosine-5-monophosph... 541 e-152
gb|AAA36114.1| IMP dehydrogenase type 1 (EC 1.1.1.205) 539 e-151
ref|NP_954530.1| inosine monophosphate dehydrogenase 2 [Rat... 539 e-151
ref|XP_533835.2| PREDICTED: similar to inosine 5-phosphate ... 538 e-151
ref|XP_001110813.1| PREDICTED: inosine monophosphate dehydr... 537 e-151
ref|XP_862810.1| PREDICTED: similar to inosine 5-phosphate ... 537 e-151
ref|XP_516452.2| PREDICTED: inosine monophosphate dehydroge... 535 e-150
ref|XP_862898.1| PREDICTED: similar to Inosine-5-monophosph... 535 e-150
ref|NP_984977.1| AER117Wp [Ashbya gossypii ATCC 10895] >gi|... 535 e-150
ref|XP_623071.1| PREDICTED: similar to Inosine-5-monophosph... 533 e-150
ref|XP_862874.1| PREDICTED: similar to Inosine-5-monophosph... 532 e-149
ref|XP_001089341.1| PREDICTED: similar to inosine monophosp... 532 e-149
ref|XP_850999.1| PREDICTED: similar to inosine monophosphat... 531 e-149
ref|XP_001505397.1| PREDICTED: similar to hCG2002013 [Ornit... 530 e-149
dbj|BAD18464.1| unnamed protein product [Homo sapiens] 530 e-148
ref|XP_001749943.1| predicted protein [Monosiga brevicollis... 530 e-148
ref|XP_001501637.1| PREDICTED: hypothetical protein [Equus ... 529 e-148
emb|CAG03265.1| unnamed protein product [Tetraodon nigrovir... 528 e-148
emb|CAI45968.1| hypothetical protein [Homo sapiens] 528 e-148
ref|NP_013656.1| Inosine monophosphate dehydrogenase, catal... 526 e-147
ref|XP_451781.1| unnamed protein product [Kluyveromyces lac... 525 e-147
ref|XP_001653775.1| inosine-5-monophosphate dehydrogenase [... 525 e-147
gb|EDN64340.1| IMP dehydrogenase [Saccharomyces cerevisiae ... 523 e-146
gb|AAW65380.1| inosine-5'-monophosphate dehydrogenase [Cand... 523 e-146
gb|EDN62491.1| IMP dehydrogenase [Saccharomyces cerevisiae ... 521 e-146
ref|XP_001384903.1| hypothetical protein PICST_65804 [Pichi... 521 e-146
emb|CAG11386.1| unnamed protein product [Tetraodon nigrovir... 521 e-146
sp|O00086|IMDH3_CANAL Probable inosine-5'-monophosphate deh... 521 e-146
ref|XP_001861658.1| inosine-5'-monophosphate dehydrogenase ... 521 e-146
gb|EDL13788.1| inosine 5'-phosphate dehydrogenase 1, isofor... 520 e-146
ref|NP_001102089.1| inosine 5'-phosphate dehydrogenase 1 [R... 520 e-145
gb|AAW65379.1| mycophenolic acid-resistant inosine-5'-monop... 520 e-145
ref|XP_309514.2| AGAP011133-PA [Anopheles gambiae str. PEST... 519 e-145
gb|AAF70813.1|AF249293_1 putative inosine 5-monophosphate d... 518 e-145
ref|NP_727441.1| raspberry CG1799-PA, isoform A [Drosophila... 516 e-144
ref|NP_012088.1| Inosine monophosphate dehydrogenase, catal... 515 e-144
ref|XP_001355544.1| GA14756-PA [Drosophila pseudoobscura] >... 513 e-143
ref|XP_001483272.1| hypothetical protein PGUG_04001 [Pichia... 512 e-143
ref|NP_013536.1| Inosine monophosphate dehydrogenase, catal... 512 e-143
ref|XP_448685.1| unnamed protein product [Candida glabrata]... 511 e-143
ref|XP_001730522.1| hypothetical protein MGL_2318 [Malassez... 510 e-142
ref|XP_001110769.1| PREDICTED: inosine monophosphate dehydr... 508 e-142
ref|XP_966518.1| PREDICTED: similar to Inosine-5-monophosph... 508 e-142
ref|XP_001641935.1| predicted protein [Nematostella vectens... 505 e-141
ref|XP_975808.1| PREDICTED: similar to Inosine-5-monophosph... 503 e-140
ref|XP_001085281.1| PREDICTED: inosine monophosphate dehydr... 503 e-140
ref|XP_638973.1| IMP dehydrogenase [Dictyostelium discoideu... 502 e-140
ref|XP_001110506.1| PREDICTED: inosine monophosphate dehydr... 501 e-140
gb|AAF13230.1|AF196975_1 inosine 5'-monophosphate dehydroge... 501 e-140
ref|XP_862783.1| PREDICTED: similar to inosine 5-phosphate ... 500 e-139
ref|XP_460442.1| hypothetical protein DEHA0F02068g [Debaryo... 499 e-139
dbj|BAB70780.1| unnamed protein product [Homo sapiens] 499 e-139
gb|EAW83650.1| IMP (inosine monophosphate) dehydrogenase 1,... 498 e-139
ref|NP_595702.1| IMP dehydrogenase Gua1 (predicted) [Schizo... 498 e-139
ref|XP_503115.1| hypothetical protein [Yarrowia lipolytica]... 495 e-138
ref|XP_001483486.1| hypothetical protein PGUG_04215 [Pichia... 494 e-138
ref|XP_975747.1| PREDICTED: similar to Inosine-5-monophosph... 493 e-137
ref|XP_001527068.1| inosine-5'-monophosphate dehydrogenase ... 492 e-137
ref|XP_001879769.1| predicted protein [Laccaria bicolor S23... 490 e-137
ref|XP_566768.1| IMP dehydrogenase [Cryptococcus neoformans... 489 e-136
dbj|BAE87359.1| unnamed protein product [Macaca fascicularis] 488 e-136
ref|YP_001838659.1| Inosine-5'-monophosphate dehydrogenase ... 486 e-135
ref|XP_001110652.1| PREDICTED: inosine monophosphate dehydr... 485 e-135
gb|AAB35628.1| inosine monophosphate dehydrogenase; IMPD [D... 484 e-135
ref|YP_798134.1| Inosine-5'-monophosphate dehydrogenase [Le... 481 e-134
ref|XP_001834217.1| hypothetical protein CC1G_09717 [Coprin... 478 e-133
ref|NP_712167.1| inosine-5'-monophosphate dehydrogenase [Le... 478 e-133
ref|XP_001509219.1| PREDICTED: similar to IMP (inosine mono... 477 e-133
ref|XP_001643968.1| hypothetical protein Kpol_1001p22 [Vand... 476 e-132
ref|XP_001245055.1| hypothetical protein CIMG_04496 [Coccid... 474 e-132
ref|XP_001187413.1| PREDICTED: hypothetical protein [Strong... 473 e-131
ref|XP_001085165.1| PREDICTED: inosine monophosphate dehydr... 467 e-129
ref|XP_749494.1| IMP dehydrogenase [Aspergillus fumigatus A... 464 e-129
ref|XP_001823965.1| hypothetical protein [Aspergillus oryza... 464 e-129
gb|AAV74388.1| inosine 5'monophosphate dehydrogenase [Toxop... 464 e-129
gb|EDP54019.1| IMP dehydrogenase, putative [Aspergillus fum... 463 e-128
ref|XP_001265922.1| IMP dehydrogenase, putative [Neosartory... 463 e-128
ref|XP_001391892.1| hypothetical protein An07g08170 [Asperg... 463 e-128
ref|XP_001272822.1| IMP dehydrogenase, putative [Aspergillu... 462 e-128
emb|CAJ70994.1| strongly similar to inosine-5'-monophosphat... 461 e-128
gb|EDU43320.1| inosine-5'-monophosphate dehydrogenase IMD2 ... 461 e-128
ref|XP_001218150.1| inosine-5'-monophosphate dehydrogenase ... 459 e-127
gb|EDN62488.1| IMP dehydrogenase [Saccharomyces cerevisiae ... 458 e-127
ref|XP_001220082.1| conserved hypothetical protein [Chaetom... 457 e-127
ref|NP_524646.4| raspberry CG1799-PB, isoform B [Drosophila... 457 e-126
gb|EEH34756.1| inosine-5'-monophosphate dehydrogenase IMD2 ... 457 e-126
ref|XP_964976.1| inosine-5'-monophosphate dehydrogenase IMD... 456 e-126
ref|XP_001908760.1| unnamed protein product [Podospora anse... 455 e-126
ref|XP_361156.2| conserved hypothetical protein [Magnaporth... 453 e-125
sp|Q12658|IMDH_PNECA Inosine-5'-monophosphate dehydrogenase... 453 e-125
ref|XP_381037.1| hypothetical protein FG00861.1 [Gibberella... 450 e-124
ref|NP_001023395.1| T22D1.3a [Caenorhabditis elegans] >gi|1... 449 e-124
ref|XP_001587025.1| conserved hypothetical protein [Sclerot... 448 e-124
ref|XP_001548411.1| inosine 5-monophosphate dehydrogenase [... 445 e-123
gb|ACO66218.1| predicted protein [Micromonas sp. RCC299] 444 e-122
ref|XP_001791107.1| hypothetical protein SNOG_00421 [Phaeos... 442 e-122
ref|XP_001670574.1| Hypothetical protein CBG05718 [Caenorha... 441 e-122
gb|EEH55423.1| predicted protein [Micromonas pusilla CCMP1545] 432 e-119
emb|CAL52091.2| IpdH inosine 5'-phosphate dehydrogenase (IC... 427 e-117
pir||T32709 IMP dehydrogenase (EC 1.1.1.205) T22D1.3 - Caen... 426 e-117
ref|XP_001416409.1| inosine 5'-phosphate dehydrogenase [Ost... 425 e-117
ref|XP_001176187.1| PREDICTED: hypothetical protein, partia... 424 e-117
ref|XP_001780012.1| predicted protein [Physcomitrella paten... 421 e-116
ref|XP_001757644.1| predicted protein [Physcomitrella paten... 421 e-116
gb|EAW83651.1| IMP (inosine monophosphate) dehydrogenase 1,... 418 e-115
ref|XP_001610614.1| inosine-5'-monophosphate dehydrogenase,... 416 e-114
ref|XP_001699045.1| hypothetical protein CHLREDRAFT_193467 ... 414 e-114
ref|XP_723782.1| inosine-5'-monophosphate dehydrogenase [Pl... 410 e-112
ref|XP_745717.1| Inosine-5'-monophosphate dehydrogenase [Pl... 410 e-112
ref|XP_678299.1| inosine-5'-monophosphate dehydrogenase [Pl... 405 e-111
ref|XP_763238.1| inosine-5'-monophosphate dehydrogenase [Th... 400 e-109
gb|ABU94684.1| inosine-5'-monophosphate dehydrogenase [Came... 397 e-109
ref|XP_001352079.1| Inosine-5'-monophosphate dehydrogenase ... 391 e-107
ref|XP_954913.1| inosine-5'-monophosphate dehydrogenase, pu... 389 e-106
ref|XP_001614740.1| inosine-5'-monophosphate dehydrogenase,... 387 e-105
gb|AAD10256.1| inosine-5'-monophosphate dehydrogenase [Plas... 387 e-105
gb|AAO40253.1| inosine monophosphate dehydrogenase [Vigna u... 387 e-105
ref|NP_001023396.1| T22D1.3b [Caenorhabditis elegans] >gi|3... 381 e-104
ref|NP_173085.1| inosine-5'-monophosphate dehydrogenase, pu... 377 e-102
emb|CAO64941.1| unnamed protein product [Vitis vinifera] 377 e-102
ref|NP_178065.1| inosine-5'-monophosphate dehydrogenase [Ar... 372 e-101
gb|AAM67120.1| inosine-5'-monophosphate dehydrogenase, puta... 371 e-100
gb|AAK09225.1|AC084320_12 putative inosine monophosphate de... 358 7e-97
ref|XP_711825.1| inosine-5'-monophosphate dehydrogenase [Ca... 358 9e-97
emb|CAB38030.1| inosine monophosphate dehydrogenase [Glycin... 354 1e-95
sp|P39567|IMDH1_YEAST Probable inosine-5'-monophosphate deh... 353 2e-95
gb|AAV73841.1| inosine 5'monophosphate dehydrogenase short ... 342 5e-92
gb|ABF99176.1| inosine-5'-monophosphate dehydrogenase, puta... 340 1e-91
gb|AAR10887.1| inosine-5'-phosphate dehydrogenase [Nicotian... 332 6e-89
ref|XP_804295.1| inosine-5'-monophosphate dehydrogenase, pu... 331 7e-89
ref|ZP_02079836.1| hypothetical protein CLOLEP_01281 [Clost... 325 5e-87
ref|YP_001306807.1| inosine-5'-monophosphate dehydrogenase ... 323 2e-86
ref|YP_001857542.1| inosine-5'-monophosphate dehydrogenase ... 319 3e-85
gb|EEJ80041.1| inosine-5'-monophosphate dehydrogenase [Kang... 318 5e-85
ref|YP_001180491.1| inosine-5'-monophosphate dehydrogenase ... 318 7e-85
ref|YP_001409640.1| inosine-5'-monophosphate dehydrogenase ... 317 1e-84
ref|YP_076743.1| inosine-5'-monophosphate dehydrogenase [Sy... 317 2e-84
ref|YP_958999.1| inosine-5'-monophosphate dehydrogenase [Ma... 317 2e-84
ref|ZP_02206927.1| hypothetical protein COPEUT_01719 [Copro... 317 2e-84
ref|YP_436057.1| inosine-5'-monophosphate dehydrogenase [Ha... 316 3e-84
ref|ZP_01892873.1| inosine-5'-monophosphate dehydrogenase [... 316 3e-84
ref|ZP_01121658.1| putative inosine-5'-monophosphate dehydr... 316 3e-84
ref|NP_214389.1| inosine monophosphate dehydrogenase [Aquif... 313 2e-83
ref|YP_001512091.1| inosine-5'-monophosphate dehydrogenase ... 313 2e-83
ref|YP_604019.1| inosine-5'-monophosphate dehydrogenase [De... 313 3e-83
ref|NP_229148.1| inosine-5'-monophosphate dehydrogenase [Th... 312 3e-83
ref|YP_001119735.1| inositol-5-monophosphate dehydrogenase ... 312 3e-83
pdb|1VRD|A Chain A, Crystal Structure Of Inosine-5'-Monopho... 312 4e-83
ref|YP_001767947.1| inosine-5'-monophosphate dehydrogenase ... 312 4e-83
ref|YP_001797406.1| inosine-5'-monophosphate dehydrogenase ... 312 4e-83
ref|YP_001739509.1| inosine-5'-monophosphate dehydrogenase ... 311 6e-83
ref|YP_753603.1| IMP dehydrogenase [Syntrophomonas wolfei s... 311 7e-83
ref|YP_001665693.1| response regulator receiver protein [Th... 311 7e-83
ref|ZP_00979930.1| COG0516: IMP dehydrogenase/GMP reductase... 311 8e-83
ref|ZP_01967358.1| hypothetical protein RUMTOR_00905 [Rumin... 311 8e-83
ref|YP_001765294.1| inosine-5'-monophosphate dehydrogenase ... 311 1e-82
ref|ZP_02074678.1| hypothetical protein CLOL250_01453 [Clos... 310 1e-82
ref|YP_369539.1| inositol-5-monophosphate dehydrogenase [Bu... 310 1e-82
ref|YP_001683839.1| inosine-5'-monophosphate dehydrogenase ... 310 2e-82
ref|YP_545250.1| inosine-5'-monophosphate dehydrogenase [Me... 310 2e-82
ref|YP_616077.1| inosine-5'-monophosphate dehydrogenase [Sp... 310 2e-82
ref|YP_001419688.1| GuaB [Bacillus amyloliquefaciens FZB42]... 309 3e-82
ref|ZP_02910335.1| inosine-5'-monophosphate dehydrogenase [... 309 3e-82
ref|ZP_02883330.1| inosine-5'-monophosphate dehydrogenase [... 309 4e-82
ref|ZP_02177021.1| inosine monophosphate dehydrogenase [Hyd... 309 4e-82
ref|YP_862533.1| IMP dehydrogenase [Gramella forsetii KT080... 309 4e-82
ref|YP_773914.1| inositol-5-monophosphate dehydrogenase [Bu... 309 4e-82
ref|ZP_02093569.1| hypothetical protein PEPMIC_00320 [Pepto... 309 4e-82
ref|NP_622249.1| IMP dehydrogenase/GMP reductase [Thermoana... 308 5e-82
ref|ZP_00533047.1| IMP dehydrogenase [Chlorobium phaeobacte... 308 5e-82
ref|YP_001599217.1| inosine-5'-monophosphate dehydrogenase ... 308 6e-82
ref|ZP_04020083.1| IMP dehydrogenase [Finegoldia magna ATCC... 308 6e-82
ref|YP_001896051.1| inosine-5'-monophosphate dehydrogenase ... 308 7e-82
ref|YP_569400.1| inositol-5-monophosphate dehydrogenase [Rh... 308 7e-82
ref|NP_420428.1| inosine-5'-monophosphate dehydrogenase [Ca... 308 7e-82
ref|NP_519550.1| inositol-5-monophosphate dehydrogenase [Ra... 308 7e-82
ref|NP_274226.1| inositol-5-monophosphate dehydrogenase [Ne... 308 8e-82
ref|NP_284115.1| inositol-5-monophosphate dehydrogenase [Ne... 308 8e-82
ref|YP_523537.1| inosine-5'-monophosphate dehydrogenase [Rh... 308 8e-82
ref|ZP_01616794.1| inositol-5-monophosphate dehydrogenase [... 308 9e-82
ref|ZP_01552004.1| IMP dehydrogenase [Methylophilales bacte... 308 9e-82
ref|ZP_01667581.1| inosine-5'-monophosphate dehydrogenase [... 307 1e-81
ref|ZP_02211058.1| hypothetical protein CLOBAR_00656 [Clost... 307 1e-81
emb|CAA39204.1| IMP dehydrogenase [Bacillus subtilis] 307 1e-81
ref|ZP_02438314.1| hypothetical protein CLOSS21_00765 [Clos... 307 1e-81
ref|YP_145862.1| inositol-5-monophosphate dehydrogenase [Ge... 307 1e-81
ref|ZP_02379271.1| inositol-5-monophosphate dehydrogenase [... 307 1e-81
ref|ZP_00946937.1| Inosine-5'-monophosphate dehydrogenase [... 307 2e-81
ref|ZP_02356071.1| inositol-5-monophosphate dehydrogenase [... 307 2e-81
ref|ZP_01128723.1| inosine-5'-monophosphate dehydrogenase [... 306 2e-81
ref|ZP_02089056.1| hypothetical protein CLOBOL_06625 [Clost... 306 2e-81
ref|YP_975144.1| inositol-5-monophosphate dehydrogenase [Ne... 306 2e-81
ref|ZP_02041332.1| hypothetical protein RUMGNA_02099 [Rumin... 306 2e-81
gb|AAX26785.2| SJCHGC05057 protein [Schistosoma japonicum] 306 2e-81
ref|YP_001898882.1| inosine-5'-monophosphate dehydrogenase ... 306 2e-81
ref|YP_001239605.1| inositol-5-monophosphate dehydrogenase ... 306 2e-81
ref|YP_786091.1| inosine-5'-monophosphate dehydrogenase [Bo... 306 3e-81
ref|YP_001303740.1| inosine-5'-monophosphate dehydrogenase ... 306 3e-81
ref|NP_387890.1| inositol-5-monophosphate dehydrogenase [Ba... 306 3e-81
ref|ZP_02008991.1| inosine-5'-monophosphate dehydrogenase [... 306 3e-81
ref|ZP_01891664.1| putative inosine-5'-monophosphate dehydr... 306 4e-81
ref|ZP_02914844.1| inosine-5'-monophosphate dehydrogenase [... 305 4e-81
ref|YP_559301.1| inositol-5-monophosphate dehydrogenase [Bu... 305 4e-81
ref|ZP_02043439.1| hypothetical protein ACTODO_00279 [Actin... 305 4e-81
ref|ZP_02862590.1| hypothetical protein ANASTE_01809 [Anaer... 305 6e-81
ref|ZP_02950650.1| inosine-5'-monophosphate dehydrogenase [... 305 6e-81
ref|ZP_02060725.1| inosine-5'-monophosphate dehydrogenase [... 305 6e-81
ref|YP_001113252.1| inosine-5'-monophosphate dehydrogenase ... 305 6e-81
ref|YP_001717214.1| inosine-5'-monophosphate dehydrogenase ... 305 7e-81
ref|YP_001124141.1| inositol-5-monophosphate dehydrogenase ... 305 7e-81
ref|ZP_03992373.1| IMP dehydrogenase [Oribacterium sinus F0... 305 8e-81
ref|YP_001568914.1| inosine-5'-monophosphate dehydrogenase ... 305 8e-81
ref|YP_001691617.1| inositol-monophosphate dehydrogenase [F... 305 9e-81
ref|YP_912073.1| inosine-5'-monophosphate dehydrogenase [Ch... 305 9e-81
ref|YP_207925.1| inositol-5-monophosphate dehydrogenase [Ne... 305 9e-81
ref|ZP_00951535.1| putative inosine-5'-monophosphate dehydr... 304 9e-81
ref|NP_947545.1| inositol-5-monophosphate dehydrogenase [Rh... 304 9e-81
ref|YP_782181.1| inositol-5-monophosphate dehydrogenase [Rh... 304 1e-80
ref|YP_726498.1| inositol-5-monophosphate dehydrogenase [Ra... 304 1e-80
ref|YP_391882.1| inosine-5'-monophosphate dehydrogenase [Th... 304 1e-80
ref|YP_002769495.1| inosine-5'-monophosphate dehydrogenase ... 304 1e-80
ref|ZP_02298794.1| inosine-5'-monophosphate dehydrogenase [... 304 1e-80
ref|YP_001020817.1| IMP dehydrogenase [Methylibium petrolei... 304 1e-80
ref|NP_900973.1| inositol-5-monophosphate dehydrogenase [Ch... 304 1e-80
ref|YP_001791093.1| inosine-5'-monophosphate dehydrogenase ... 303 2e-80
ref|YP_296065.1| inositol-5-monophosphate dehydrogenase [Ra... 303 2e-80
ref|YP_001099659.1| IMP dehydrogeanse [Herminiimonas arseni... 303 2e-80
ref|YP_108726.1| inositol-5-monophosphate dehydrogenase [Bu... 303 2e-80
ref|YP_001752794.1| inosine-5'-monophosphate dehydrogenase ... 303 2e-80
ref|YP_411895.1| inosine-5'-monophosphate dehydrogenase [Ni... 303 3e-80
ref|YP_001205198.1| inositol-5-monophosphate dehydrogenase ... 303 3e-80
gb|AAX77966.1| unknown protein [synthetic construct] 303 3e-80
ref|ZP_01516974.1| inosine-5'-monophosphate dehydrogenase [... 303 3e-80
ref|YP_001156201.1| inositol-5-monophosphate dehydrogenase ... 302 3e-80
ref|ZP_01521990.1| inosine-5'-monophosphate dehydrogenase [... 302 3e-80
ref|ZP_01051393.1| putative inosine-5'-monophosphate dehydr... 302 4e-80
ref|YP_002785219.1| putative malate dehydrogenase [Deinococ... 302 4e-80
ref|ZP_02117013.1| Malate dehydrogenase [Methylobacterium n... 302 4e-80
ref|ZP_01739391.1| inosine-5'-monophosphate dehydrogenase [... 302 4e-80
ref|ZP_02850469.1| inosine-5'-monophosphate dehydrogenase [... 302 5e-80
ref|YP_486800.1| inositol-5-monophosphate dehydrogenase [Rh... 301 6e-80
ref|YP_318752.1| inositol-5-monophosphate dehydrogenase [Ni... 301 6e-80
ref|YP_170270.1| Inosine-5-monophosphate dehydrogenase [Fra... 301 7e-80
ref|YP_001695789.1| Inosine-5'-monophosphate dehydrogenase ... 301 7e-80
ref|NP_240886.1| inositol-5-monophosphate dehydrogenase [Ba... 301 7e-80
ref|YP_429965.1| inosine-5'-monophosphate dehydrogenase [Mo... 301 7e-80
ref|YP_001260911.1| inosine-5'-monophosphate dehydrogenase ... 301 7e-80
ref|ZP_02039215.1| hypothetical protein BACCAP_04867 [Bacte... 301 8e-80
ref|YP_760508.1| inosine-5'-monophosphate dehydrogenase [Hy... 301 9e-80
gb|EEJ98321.1| inosine-5'-monophosphate dehydrogenase [Ther... 301 9e-80
>sp|P50098|IMDH_TRYBB Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH)
(IMPD)
gb|AAB46420.1| inosine-5'-monophosphate dehydrogenase
Length = 512
Score = 1021 bits (2639), Expect = 0.0, Method: Composition-based stats.
Identities = 512/512 (100%), Positives = 512/512 (100%)
Query: 1 MENTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLP 60
MENTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLP
Sbjct: 1 MENTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLP 60
Query: 61 LVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPD 120
LVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPD
Sbjct: 61 LVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPD 120
Query: 121 VPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMT 180
VPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMT
Sbjct: 121 VPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMT 180
Query: 181 VERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLC 240
VERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLC
Sbjct: 181 VERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLC 240
Query: 241 AAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVT 300
AAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVT
Sbjct: 241 AAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVT 300
Query: 301 QDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGG 360
QDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGG
Sbjct: 301 QDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGG 360
Query: 361 LRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRES 420
LRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRES
Sbjct: 361 LRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRES 420
Query: 421 GKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEG 480
GKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEG
Sbjct: 421 GKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEG 480
Query: 481 QVLFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
QVLFNRRTLTAQSEGAVHSLHHYERKLFASKL
Sbjct: 481 QVLFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
>ref|XP_828081.1| inosine-5'-monophosphate dehydrogenase [Trypanosoma brucei TREU927]
gb|EAN78969.1| inosine-5'-monophosphate dehydrogenase [Trypanosoma brucei]
Length = 447
Score = 885 bits (2286), Expect = 0.0, Method: Composition-based stats.
Identities = 446/447 (99%), Positives = 447/447 (100%)
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST
Sbjct: 1 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 60
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYP 185
IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYP
Sbjct: 61 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYP 120
Query: 186 IKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATS 245
IKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATS
Sbjct: 121 IKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATS 180
Query: 246 TREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAK 305
TREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAK
Sbjct: 181 TREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAK 240
Query: 306 NLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVG 365
NLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVG
Sbjct: 241 NLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVG 300
Query: 366 DVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYL 425
DVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYL
Sbjct: 301 DVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYL 360
Query: 426 SENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFN 485
SENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFN
Sbjct: 361 SENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFN 420
Query: 486 RRTLTAQSEGAVHSLHHYERKLFASKL 512
RR+LTAQSEGAVHSLHHYERKLFASKL
Sbjct: 421 RRSLTAQSEGAVHSLHHYERKLFASKL 447
>ref|XP_805772.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma cruzi
strain CL Brener]
gb|EAN83921.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma
cruzi]
Length = 512
Score = 870 bits (2247), Expect = 0.0, Method: Composition-based stats.
Identities = 417/512 (81%), Positives = 467/512 (91%)
Query: 1 MENTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLP 60
M N +LRTKT+RDG TAEELF DGL+++DFIILPGFIDF +S V VSGQFTK I LH+P
Sbjct: 1 MANVDLRTKTIRDGVTAEELFQSDGLTYSDFIILPGFIDFGASDVQVSGQFTKKIRLHIP 60
Query: 61 LVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPD 120
+VSSPMDTVTES MAR MALMGGIGV+HNNCTV+ Q +MVRSVK++RNGFIMKPKSV P+
Sbjct: 61 IVSSPMDTVTESEMARTMALMGGIGVLHNNCTVQHQVQMVRSVKMFRNGFIMKPKSVGPE 120
Query: 121 VPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMT 180
P+S I I +EKGISGILVTE G++DGKLLGIVC+KDIDFVKD S PVSQ+MT+RE+MT
Sbjct: 121 TPISVIHEINAEKGISGILVTENGRHDGKLLGIVCSKDIDFVKDVSLPVSQFMTKRESMT 180
Query: 181 VERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLC 240
VERYPI+LEEAMDVLNRSRHGYLPVLNDK EV+CLCSRRDAVRAR YPNSSLDRNGHLLC
Sbjct: 181 VERYPIRLEEAMDVLNRSRHGYLPVLNDKGEVMCLCSRRDAVRARVYPNSSLDRNGHLLC 240
Query: 241 AAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVT 300
AAATSTRE DK RVAAL+ AG+DVL+LDSSQGNT YQVSFI+WVKKT+PHLEVVAGNVVT
Sbjct: 241 AAATSTREEDKARVAALAGAGVDVLLLDSSQGNTFYQVSFIKWVKKTFPHLEVVAGNVVT 300
Query: 301 QDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGG 360
QDQAKNLIDAGAD++RIGMGSGSICITQEVLACGRPQATA+YKV RYAASRGVPC+ADGG
Sbjct: 301 QDQAKNLIDAGADAIRIGMGSGSICITQEVLACGRPQATAVYKVCRYAASRGVPCIADGG 360
Query: 361 LRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRES 420
LR+VGD+CKALA+GAN AMLGSM+AGTSETPG YFFK+G+RLK YRGMGS++AM QG+ES
Sbjct: 361 LRSVGDICKALAIGANTAMLGSMLAGTSETPGSYFFKEGLRLKAYRGMGSLEAMSQGKES 420
Query: 421 GKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEG 480
GKRYLSE ET+QVAQGV+G VLDKGSV KLLAYIHKGLQQSAQDIGE+ FDA+REK+YEG
Sbjct: 421 GKRYLSEKETVQVAQGVSGTVLDKGSVTKLLAYIHKGLQQSAQDIGEIGFDAVREKMYEG 480
Query: 481 QVLFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
QVLFNRR+ AQ EG VHSLH +E+ LF SKL
Sbjct: 481 QVLFNRRSPIAQMEGGVHSLHSFEKNLFTSKL 512
>ref|XP_815489.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma cruzi
strain CL Brener]
gb|EAN93638.1| inosine-5'-monophosphate dehydrogenase, putative [Trypanosoma
cruzi]
Length = 512
Score = 865 bits (2236), Expect = 0.0, Method: Composition-based stats.
Identities = 416/512 (81%), Positives = 467/512 (91%)
Query: 1 MENTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLP 60
M N +LRTKT+RDG TAEELF DGL+++DF+ILPGFIDF +S V VSGQFTK I LH+P
Sbjct: 1 MVNVDLRTKTIRDGVTAEELFQSDGLTYSDFVILPGFIDFGASDVQVSGQFTKKIRLHIP 60
Query: 61 LVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPD 120
+VSSPMDTVTES MAR MALMGGIGV+HNNCTV+ Q +MVRSVK++RNGFIMKPKSV PD
Sbjct: 61 IVSSPMDTVTESEMARTMALMGGIGVLHNNCTVQHQVQMVRSVKMFRNGFIMKPKSVGPD 120
Query: 121 VPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMT 180
P+S I I ++KGISGILVTE G++DGKLLGIVC+KDIDFVKD S PVSQ+MT+RE+MT
Sbjct: 121 TPISVIHEINADKGISGILVTENGRHDGKLLGIVCSKDIDFVKDVSLPVSQFMTKRESMT 180
Query: 181 VERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLC 240
VERYPI+LEEAMDVLNRSRHGYLPVLNDK EV+CLCSRRDAVRAR YPNSSLDRNGHLLC
Sbjct: 181 VERYPIRLEEAMDVLNRSRHGYLPVLNDKGEVMCLCSRRDAVRARVYPNSSLDRNGHLLC 240
Query: 241 AAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVT 300
AAATSTRE DK RVAAL+ AG+DVL+LDSSQGNTIYQVSFI+W KKT+PHLEVVAGNVVT
Sbjct: 241 AAATSTREEDKARVAALAGAGVDVLLLDSSQGNTIYQVSFIKWAKKTFPHLEVVAGNVVT 300
Query: 301 QDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGG 360
QDQAKNLIDAGAD++RIGMGSGSICITQEVLACGRPQATA+YKV RYAASRGVPC+ADGG
Sbjct: 301 QDQAKNLIDAGADAIRIGMGSGSICITQEVLACGRPQATAVYKVCRYAASRGVPCIADGG 360
Query: 361 LRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRES 420
LR+VGD+CKALA+GAN AMLGSM+AGTSETPG YFFK+G+RLK YRGMGS++AM QG+ES
Sbjct: 361 LRSVGDICKALAIGANTAMLGSMLAGTSETPGRYFFKEGLRLKTYRGMGSLEAMSQGKES 420
Query: 421 GKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEG 480
GKRYLSE ET+QVAQGV+G VLDKGSV KLLAYIHKGLQQSAQDIGE+SFDA+REK+Y G
Sbjct: 421 GKRYLSEKETVQVAQGVSGTVLDKGSVTKLLAYIHKGLQQSAQDIGEISFDAVREKMYGG 480
Query: 481 QVLFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
QVLFNRR+ AQ EG VHSLH +E+ LF SKL
Sbjct: 481 QVLFNRRSPIAQMEGGVHSLHSFEKNLFTSKL 512
>ref|XP_001465126.1| inosine-5'-monophosphate dehydrogenase [Leishmania infantum JPCM5]
sp|P21620|IMDH_LEIDO Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH)
(IMPD)
gb|AAA29253.1| IMP dehydrogenase
emb|CAM67369.1| inosine-5'-monophosphate dehydrogenase [Leishmania infantum]
Length = 514
Score = 808 bits (2087), Expect = 0.0, Method: Composition-based stats.
Identities = 389/510 (76%), Positives = 449/510 (88%)
Query: 3 NTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLV 62
N N R KT++DG TAEELF DGL++NDFIILPGFIDF ++ VN+SGQFTK I LH+P+V
Sbjct: 5 NANYRIKTIKDGCTAEELFRGDGLTYNDFIILPGFIDFGAADVNISGQFTKRIRLHIPIV 64
Query: 63 SSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVP 122
SSPMDT+TE+ MA+ MALMGG+GV+HNNCTVE+Q MV+SVK YRNGFI KPKSV P+ P
Sbjct: 65 SSPMDTITENEMAKTMALMGGVGVLHNNCTVERQVEMVKSVKAYRNGFISKPKSVPPNTP 124
Query: 123 VSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVE 182
+S I IK EKGISGILVTE G GKLLGIVCTKDID+VK+ PVS MTRRE MTVE
Sbjct: 125 ISNIIRIKEEKGISGILVTENGDPHGKLLGIVCTKDIDYVKNKDTPVSAVMTRREKMTVE 184
Query: 183 RYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAA 242
R PI+LEEAMDVLNRSR+GYLP++N+ DEVV LCSRRDAVRARDYP+S+LD++G L+CAA
Sbjct: 185 RAPIQLEEAMDVLNRSRYGYLPIVNENDEVVNLCSRRDAVRARDYPHSTLDKSGRLICAA 244
Query: 243 ATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQD 302
ATSTR DK RVAAL++ G+DVLVLDSSQGNTIYQ++FI+WVK TYPHLEVVAGNVVTQD
Sbjct: 245 ATSTRPEDKRRVAALADVGVDVLVLDSSQGNTIYQIAFIKWVKSTYPHLEVVAGNVVTQD 304
Query: 303 QAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLR 362
QAKNLIDAGAD +RIGMGSGSICITQEVLACGRPQ TA+YKVA+Y ASRGVPC ADGGLR
Sbjct: 305 QAKNLIDAGADGIRIGMGSGSICITQEVLACGRPQGTAVYKVAQYCASRGVPCTADGGLR 364
Query: 363 NVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGK 422
VGD+CKALA+GAN AMLG M++GT+ETPGEYFFK G+RLK YRGMGS++AM QG+ESGK
Sbjct: 365 QVGDICKALAIGANCAMLGGMLSGTTETPGEYFFKGGVRLKVYRGMGSLEAMSQGKESGK 424
Query: 423 RYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQV 482
RYLSENE +QVAQGV+G V+DKGS KL+AY+ KGLQQSAQDIGE+SFDAIREK+Y GQV
Sbjct: 425 RYLSENEAVQVAQGVSGNVVDKGSAAKLIAYVSKGLQQSAQDIGEISFDAIREKMYAGQV 484
Query: 483 LFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
LF+RR+ TAQ EG VHSLH YE+KLFA+K+
Sbjct: 485 LFSRRSPTAQGEGGVHSLHSYEKKLFAAKM 514
>ref|XP_001682745.1| inosine-5'-monophosphate dehydrogenase [Leishmania major]
emb|CAJ07253.1| inosine-5'-monophosphate dehydrogenase [Leishmania major]
Length = 514
Score = 807 bits (2084), Expect = 0.0, Method: Composition-based stats.
Identities = 388/510 (76%), Positives = 448/510 (87%)
Query: 3 NTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLV 62
N N R KT++DG TAEELF DGL++NDFIILPGFIDF ++ VN+SGQFTK I LH+P+V
Sbjct: 5 NANYRIKTIKDGCTAEELFRGDGLTYNDFIILPGFIDFGAADVNISGQFTKRIRLHIPIV 64
Query: 63 SSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVP 122
SSPMDT+TE+ MA+ MALMGG+GV+HNNCTVE+Q MV+SVK YRNGFI KPKSV P+ P
Sbjct: 65 SSPMDTITENEMAKTMALMGGVGVLHNNCTVERQVEMVKSVKAYRNGFISKPKSVPPNTP 124
Query: 123 VSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVE 182
+S I IK EKGISGILVTE G GKLLGIVCTKDID+VK+ PVS MTRRE MTVE
Sbjct: 125 ISNIIRIKEEKGISGILVTENGDPHGKLLGIVCTKDIDYVKNKDTPVSAVMTRREKMTVE 184
Query: 183 RYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAA 242
R PI+LEEAMDVLNRSR+GYLP++N+ EVV LCSRRDAVRARDYP+S+LD++G L+CAA
Sbjct: 185 RAPIQLEEAMDVLNRSRYGYLPIVNENGEVVNLCSRRDAVRARDYPHSTLDKSGRLICAA 244
Query: 243 ATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQD 302
ATSTR DK RVAAL++ G+DVLVLDSSQGNTIYQ++FI+WVK TYPHLEVVAGNVVTQD
Sbjct: 245 ATSTRPEDKRRVAALADVGVDVLVLDSSQGNTIYQIAFIKWVKSTYPHLEVVAGNVVTQD 304
Query: 303 QAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLR 362
QAKNLIDAGAD +RIGMGSGSICITQEVLACGRPQ TA+YKVA+Y ASRGVPC ADGGLR
Sbjct: 305 QAKNLIDAGADGIRIGMGSGSICITQEVLACGRPQGTAVYKVAQYCASRGVPCTADGGLR 364
Query: 363 NVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGK 422
VGD+CKALA+GAN AMLG M++GT+ETPGEYFFK G+RLK YRGMGS++AM QG+ESGK
Sbjct: 365 QVGDICKALAIGANCAMLGGMLSGTTETPGEYFFKGGVRLKVYRGMGSLEAMSQGKESGK 424
Query: 423 RYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQV 482
RYLSENE +QVAQGV+G V+DKGS KL+AY+ KGLQQ+AQDIGE+SFDAIREK+Y GQV
Sbjct: 425 RYLSENEVIQVAQGVSGNVVDKGSAAKLIAYVSKGLQQAAQDIGEISFDAIREKMYAGQV 484
Query: 483 LFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
LFNRR+ TAQ EG VHSLH YE+KLFA+K+
Sbjct: 485 LFNRRSPTAQGEGGVHSLHSYEKKLFAAKM 514
>gb|AAR17482.1| inosine 5' monophosphate dehydrogenase [Leishmania amazonensis]
Length = 514
Score = 807 bits (2084), Expect = 0.0, Method: Composition-based stats.
Identities = 389/510 (76%), Positives = 448/510 (87%)
Query: 3 NTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLV 62
N N R KT++DG TAEELF DGL++NDFIILPGFIDF +S VN+SGQFTK I LH+P+V
Sbjct: 5 NANYRIKTIKDGCTAEELFQGDGLTYNDFIILPGFIDFGASDVNISGQFTKRIRLHIPIV 64
Query: 63 SSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVP 122
SSPMDT+TE+ MA+ MALMGG+GV+HNNCTVE+Q MV+SVK YRNGFI KPKSV P+ P
Sbjct: 65 SSPMDTITENEMAKTMALMGGVGVLHNNCTVERQVEMVKSVKAYRNGFISKPKSVPPNTP 124
Query: 123 VSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVE 182
+S I IK EKGISGILVTE G GKLLGIVCTKDID+VK+ PVS MTRRE MTVE
Sbjct: 125 ISKIIRIKEEKGISGILVTENGDPHGKLLGIVCTKDIDYVKNKDTPVSAVMTRREKMTVE 184
Query: 183 RYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAA 242
R PI+LEEAMDVLNRSR+GYLP++N+ EVV LCSRRDAVRARDYP+S+LD++G L+CAA
Sbjct: 185 RAPIQLEEAMDVLNRSRYGYLPIVNENGEVVNLCSRRDAVRARDYPHSTLDKSGRLICAA 244
Query: 243 ATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQD 302
ATSTR DK RVA L+E G+DVLVLDSSQGNTIYQ++FI+WVK TYPHLEVVAGNVVTQD
Sbjct: 245 ATSTRPEDKRRVATLAEVGVDVLVLDSSQGNTIYQIAFIKWVKSTYPHLEVVAGNVVTQD 304
Query: 303 QAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLR 362
QAKNLIDAGAD +RIGMGSGSICITQEVLACGRPQ TA+YKVA+Y ASRGVPC ADGGLR
Sbjct: 305 QAKNLIDAGADGIRIGMGSGSICITQEVLACGRPQGTAVYKVAQYCASRGVPCTADGGLR 364
Query: 363 NVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGK 422
VGD+CKALA+GAN AMLG M++GT+ETPGEYFFK G+RLK YRGMGS++AM QG+ESGK
Sbjct: 365 QVGDICKALAIGANCAMLGGMLSGTTETPGEYFFKGGVRLKVYRGMGSLEAMNQGKESGK 424
Query: 423 RYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQV 482
RYLSENE +QVAQGV+G+V+DKGS KL+AY+ KGLQQSAQDIGE+SFDAIREK+Y GQV
Sbjct: 425 RYLSENEAVQVAQGVSGSVVDKGSAAKLIAYVSKGLQQSAQDIGEISFDAIREKMYAGQV 484
Query: 483 LFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
LF+RR+ TAQ EG VHSLH YE+KLFA+K+
Sbjct: 485 LFSRRSPTAQGEGGVHSLHSYEKKLFAAKM 514
>ref|XP_001564275.1| inosine-5'-monophosphate dehydrogenase [Leishmania braziliensis
MHOM/BR/75/M2904]
emb|CAM38334.1| inosine-5'-monophosphate dehydrogenase [Leishmania braziliensis]
Length = 514
Score = 804 bits (2076), Expect = 0.0, Method: Composition-based stats.
Identities = 386/510 (75%), Positives = 447/510 (87%)
Query: 3 NTNLRTKTLRDGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLV 62
N N R K ++DG TAEELF DGL++NDFIILPGFIDF ++ VN+SGQFTK I LH+P+V
Sbjct: 5 NANYRIKVIKDGCTAEELFQGDGLTYNDFIILPGFIDFGAADVNISGQFTKQIRLHIPIV 64
Query: 63 SSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVP 122
SSPMDT+TE+ MA+ MALMGG+GV+HNNCTVE+Q MV+SVK YRNGFI KPKSV+P+ P
Sbjct: 65 SSPMDTITENEMAKTMALMGGVGVLHNNCTVERQVEMVKSVKAYRNGFISKPKSVTPNTP 124
Query: 123 VSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVE 182
+S I IK KGISGILVTE G GKLLGIVCTKDID+VK PVS MTRR+ MTVE
Sbjct: 125 ISEIIRIKEGKGISGILVTENGDPHGKLLGIVCTKDIDYVKKKETPVSAVMTRRDKMTVE 184
Query: 183 RYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAA 242
R PI+LEEAMDVLNRSRHGYLP++N DE+V LCSRRDAVRARDYP+S+LD++G L+CAA
Sbjct: 185 RAPIQLEEAMDVLNRSRHGYLPIVNGNDEIVYLCSRRDAVRARDYPHSTLDKSGRLICAA 244
Query: 243 ATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQD 302
ATSTR DK RVAAL+E G+DVLVLDSSQGNTIYQ++FI+W+K TYPHLEVVAGNVVTQD
Sbjct: 245 ATSTRPEDKRRVAALAEVGVDVLVLDSSQGNTIYQIAFIKWIKSTYPHLEVVAGNVVTQD 304
Query: 303 QAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLR 362
QAKNLIDAGAD +RIGMGSGSICITQEVLACGRPQ TA++KVA+Y ASRGVPC ADGGLR
Sbjct: 305 QAKNLIDAGADGIRIGMGSGSICITQEVLACGRPQGTAVFKVAQYCASRGVPCTADGGLR 364
Query: 363 NVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGK 422
VGD+CKALA+GAN AMLG M++GT+ETPGEYFFK G+RLK YRGMGS++AM QG+ESGK
Sbjct: 365 QVGDICKALAIGANCAMLGGMLSGTTETPGEYFFKGGVRLKVYRGMGSLEAMSQGKESGK 424
Query: 423 RYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQV 482
RYLSENE +QVAQGV+G V+DKGS KL+AYI KGLQQSAQDIGE+SFDAIREK+Y GQV
Sbjct: 425 RYLSENEVVQVAQGVSGNVVDKGSAEKLIAYIAKGLQQSAQDIGEISFDAIREKLYAGQV 484
Query: 483 LFNRRTLTAQSEGAVHSLHHYERKLFASKL 512
LF+RR++TAQ EG VHSLH YE+KLFA+K+
Sbjct: 485 LFSRRSVTAQGEGGVHSLHSYEKKLFAAKM 514
>emb|CAI21140.1| novel protein similar to vertebrate IMP (inosine monophosphate)
dehydrogenase 1 (IMPDH1) [Danio rerio]
Length = 539
Score = 561 bits (1446), Expect = e-158, Method: Composition-based stats.
Identities = 277/503 (55%), Positives = 370/503 (73%), Gaps = 3/503 (0%)
Query: 9 KTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMD 67
+++RDG TAEELFS+ DG+++NDF+ILPGFIDF S +V+++ TK I L PL+SSPMD
Sbjct: 37 QSVRDGHTAEELFSKGDGMTYNDFLILPGFIDFTSDEVDLTSALTKKITLKTPLISSPMD 96
Query: 68 TVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIR 127
TVTESSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V +
Sbjct: 97 TVTESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKRFEQGFITDPVVLSPHHTVGDVL 156
Query: 128 NIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYP 185
K G SGI +TE GK KL+GIV ++DIDF+ KD + + + MT+RE++ V
Sbjct: 157 EAKVRHGFSGIPITETGKMGSKLVGIVTSRDIDFLSEKDNNKYLEEAMTKREDLVVAPAG 216
Query: 186 IKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATS 245
+ L+EA D+L RS+ G LP++NDKDE+V + +R D + RDYP +S D LLC AA
Sbjct: 217 VTLKEANDILQRSKKGKLPIVNDKDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIG 276
Query: 246 TREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAK 305
TRE DK R+ L+++G+D++VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAK
Sbjct: 277 TREDDKYRLDLLTQSGVDMVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAK 336
Query: 306 NLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVG 365
NLIDAG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG
Sbjct: 337 NLIDAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVG 396
Query: 366 DVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYL 425
V KAL++GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY
Sbjct: 397 HVVKALSLGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNTSSQKRYF 456
Query: 426 SENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFN 485
SE + ++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F
Sbjct: 457 SEGDKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSVLRSMMYSGELKFE 516
Query: 486 RRTLTAQSEGAVHSLHHYERKLF 508
+RT++AQ EG VH LH +E++L+
Sbjct: 517 KRTMSAQVEGGVHGLHSFEKRLY 539
>emb|CAK04261.1| novel protein similar to vertebrate IMP (inosine monophosphate)
dehydrogenase 1 (IMPDH1) [Danio rerio]
Length = 534
Score = 557 bits (1436), Expect = e-157, Method: Composition-based stats.
Identities = 278/499 (55%), Positives = 363/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF S +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 36 DGLTAQQLFAIGDGLTYNDFLILPGFIDFISDEVDLTSALTRKITLKTPLISSPMDTVTE 95
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
SSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 96 SSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSPRHTVGDVFEAKV 155
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI VTE GK KL+GIV ++DIDF+ KD P+ + MT+RE++ V + L+
Sbjct: 156 RHGFSGIPVTETGKMGSKLVGIVTSRDIDFLSEKDYDRPLEESMTKREDLVVAPAGVTLK 215
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA D+L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 216 EANDILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGTRED 275
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+DV+VLDSSQGN+++Q+S I ++K+ YP L+VV GNVVT QAKNLID
Sbjct: 276 DKYRLDLLMQAGVDVIVLDSSQGNSVFQISMINYIKQKYPELQVVGGNVVTAAQAKNLID 335
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG V K
Sbjct: 336 AGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVK 395
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 396 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNNSSQKRYFSEGD 455
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 456 KVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKFEKRTM 515
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 516 SAQVEGGVHGLHSYEKRLY 534
>ref|NP_001082410.1| similar to inosine 5'-phosphate dehydrogenase 2 [Xenopus laevis]
gb|AAH42315.1| MGC53627 protein [Xenopus laevis]
Length = 514
Score = 556 bits (1433), Expect = e-156, Method: Composition-based stats.
Identities = 277/499 (55%), Positives = 365/499 (73%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF + DGL++NDF+ILPG+IDF + +V+++ TK I L P+VSSPMDTVTE
Sbjct: 16 DGLTAQQLFGAGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPMVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
++MA AMAL GGIGVIH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 ANMAIAMALTGGIGVIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKHCVRHVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVK--DASAPVSQYMTRRENMTVERYPIKLE 189
G GI +TE GK KL GI+ ++DIDF+K D +S+ MTRRE++ V + L+
Sbjct: 136 RHGFCGIPITENGKMGSKLAGIISSRDIDFLKAEDHDLALSEIMTRREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N DE+V + +R D + RDYP +S D LLC AAT T E
Sbjct: 196 EANEILQRSKKGKLPIVNGDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAATGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+D +VLDSSQGN+I+Q++ I+++K+ YP L+V+AGNVVT QAKNLID
Sbjct: 256 DKYRLDLLVQAGVDAVVLDSSQGNSIFQINMIKYIKEKYPDLQVIAGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AGAD+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNVSSQKRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT+
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFIPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++LF
Sbjct: 496 SAQVEGGVHGLHSYEKRLF 514
>ref|XP_001252299.1| PREDICTED: inosine monophosphate dehydrogenase 1 [Bos taurus]
Length = 660
Score = 553 bits (1425), Expect = e-155, Method: Composition-based stats.
Identities = 269/499 (53%), Positives = 360/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 162 DGLTAQQLFANADGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVTE 221
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 222 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKI 281
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 282 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRNELVVAPAGVTLK 341
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 342 EANEILQRSKKGKLPIVNDRDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRED 401
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 402 DKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 461
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 462 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVK 521
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 522 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 581
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 582 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 641
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 642 SAQIEGGVHGLHSYEKRLY 660
>ref|NP_001002177.1| hypothetical protein LOC431724 [Danio rerio]
gb|AAH74090.1| Zgc:91911 [Danio rerio]
emb|CAN87720.1| novel protein (zgc:91911) [Danio rerio]
gb|AAI65226.1| Zgc:91911 protein [synthetic construct]
Length = 544
Score = 553 bits (1425), Expect = e-155, Method: Composition-based stats.
Identities = 276/494 (55%), Positives = 358/494 (72%), Gaps = 3/494 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF S +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 16 DGLTAQQLFAIGDGLTYNDFLILPGFIDFISDEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
SSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 76 SSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSPRHTVGDVFEAKV 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI VTE GK KL+GIV ++DIDF+ KD P+ + MT+RE++ V + L+
Sbjct: 136 RHGFSGIPVTETGKMGSKLVGIVTSRDIDFLSEKDYDRPLEESMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA D+L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANDILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+DV+VLDSSQGN+++Q+S I ++K+ YP L+VV GNVVT QAKNLID
Sbjct: 256 DKYRLDLLMQAGVDVIVLDSSQGNSVFQISMINYIKQKYPELQVVGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNNSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 436 KVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHY 503
+AQ EG VH LH Y
Sbjct: 496 SAQVEGGVHGLHSY 509
>ref|NP_001014391.1| hypothetical protein LOC338306 [Danio rerio]
emb|CAI21139.1| novel protein similar to vertebrate IMP (inosine monophosphate)
dehydrogenase 1 (IMPDH1) [Danio rerio]
gb|AAH91790.1| Si:dkey-31f5.7 [Danio rerio]
Length = 514
Score = 553 bits (1425), Expect = e-155, Method: Composition-based stats.
Identities = 273/499 (54%), Positives = 365/499 (73%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG +A++LF+ DGL++NDF+ILPGFIDF S +V+++ TK I L PL+SSPMDTVTE
Sbjct: 16 DGLSAQQLFAVGDGLTYNDFLILPGFIDFTSDEVDLTSALTKKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
SSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 76 SSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKRFEQGFITDPVVLSPHHTVGDVLEAKV 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE GK KL+GIV ++DIDF+ KD + + + MT+RE++ V + L+
Sbjct: 136 RHGFSGIPITETGKMGSKLVGIVTSRDIDFLSEKDNNKYLEEAMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA D+L RS+ G LP++NDKDE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANDILQRSKKGKLPIVNDKDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L+++G+D++VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQSGVDMVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
AL++GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALSLGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNTSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 436 KVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSVLRSMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH +E++L+
Sbjct: 496 SAQVEGGVHGLHSFEKRLY 514
>ref|NP_001025772.1| inosine monophosphate dehydrogenase 2 [Gallus gallus]
emb|CAH65030.1| hypothetical protein [Gallus gallus]
Length = 514
Score = 552 bits (1423), Expect = e-155, Method: Composition-based stats.
Identities = 272/499 (54%), Positives = 364/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LFS DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFSCGDGLTYNDFLILPGYIDFTADQVDLTSALTKRITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP+ V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPNDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDAS--APVSQYMTRRENMTVERYPIKLE 189
G GI +T+ GK GKL+GI+ ++DIDF+K++ P+ + MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDNGKMGGKLVGIISSRDIDFLKESEHDLPLGEIMTKREDLVVAPSGVMLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDSKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+D +VLDSSQGN+I+Q++ I+++K+ YP+L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLVQAGVDAVVLDSSQGNSIFQINMIKYIKEKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNLGSQNRYFSETD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFIPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTT 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++LF
Sbjct: 496 SAQVEGGVHGLHSYEKRLF 514
>ref|NP_001071309.1| inosine monophosphate dehydrogenase 1 [Bos taurus]
gb|AAI26585.1| IMP (inosine monophosphate) dehydrogenase 1 [Bos taurus]
Length = 571
Score = 550 bits (1418), Expect = e-155, Method: Composition-based stats.
Identities = 269/499 (53%), Positives = 360/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 73 DGLTAQQLFANADGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVTE 132
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 133 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKI 192
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 193 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRNELVVAPAGVTLK 252
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 253 EANEILQRSKKGKLPIVNDRDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRED 312
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 313 DKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 372
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 373 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVK 432
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 433 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 492
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 493 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 552
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 553 SAQIEGGVHGLHSYEKRLY 571
>ref|NP_899066.1| inosine monophosphate dehydrogenase 1 isoform b [Homo sapiens]
gb|EAL24311.1| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
gb|AAH33622.2| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
Length = 563
Score = 549 bits (1415), Expect = e-154, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 359/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 65 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 124
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 125 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 184
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 185 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 244
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 245 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 304
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 305 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 364
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 365 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 424
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 425 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 484
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 485 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 544
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 545 SAQIEGGVHGLHSYEKRLY 563
>ref|NP_001017283.1| IMP (inosine monophosphate) dehydrogenase 1 [Xenopus tropicalis]
emb|CAJ83974.1| IMP (inosine monophosphate) dehydrogenase 1 [Xenopus tropicalis]
Length = 514
Score = 549 bits (1415), Expect = e-154, Method: Composition-based stats.
Identities = 273/499 (54%), Positives = 362/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA+ LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 16 DGLTAQHLFANSDGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
S MA AMALMGGIG+IH+NCT E QA VR VK + GFI P +S + V + K+
Sbjct: 76 SDMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSLNHTVGDVFEAKN 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI VTE GK KL+GIV ++DIDF+ KD S +S+ MT+R+ + V + L+
Sbjct: 136 RHGFSGIPVTETGKMGSKLVGIVTSRDIDFLTEKDYSTYLSEVMTKRDELVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDCRKQLLCGAAIGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQAGVDVVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDALRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNTSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ +RT+
Sbjct: 436 KVKVAQGVSGSIQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKLEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 496 SAQVEGGVHGLHSYEKRLY 514
>ref|NP_001096075.1| inosine monophosphate dehydrogenase 1 isoform c [Homo sapiens]
Length = 589
Score = 548 bits (1413), Expect = e-154, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 359/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 91 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 150
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 151 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 210
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 211 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 270
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 271 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 330
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 331 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 390
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 391 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 450
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 451 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 510
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 511 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 570
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 571 SAQIEGGVHGLHSYEKRLY 589
>sp|P20839|IMDH1_HUMAN Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1)
(IMPDH-I) (IMPD 1)
Length = 514
Score = 548 bits (1413), Expect = e-154, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 359/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 16 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 76 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 136 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 436 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 496 SAQIEGGVHGLHSYEKRLY 514
>ref|NP_000874.2| inosine monophosphate dehydrogenase 1 isoform a [Homo sapiens]
gb|EAL24310.1| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
Length = 599
Score = 548 bits (1413), Expect = e-154, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 359/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 101 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 160
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 161 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 220
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 221 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 280
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 281 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 340
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 341 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 400
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 401 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 460
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 461 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 520
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 521 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 580
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 581 SAQIEGGVHGLHSYEKRLY 599
>gb|EAW64946.1| hCG2002013, isoform CRA_a [Homo sapiens]
Length = 584
Score = 548 bits (1412), Expect = e-154, Method: Composition-based stats.
Identities = 271/499 (54%), Positives = 363/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 86 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 145
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 146 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 205
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V I L+
Sbjct: 206 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLK 265
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 266 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 325
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K YP+L+V+ GNVVT QAKNLID
Sbjct: 326 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 385
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 386 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 445
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 446 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 505
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 506 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 565
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 566 SAQVEGGVHSLHSYEKRLF 584
>gb|AAA36112.1| inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)
Length = 514
Score = 548 bits (1412), Expect = e-154, Method: Composition-based stats.
Identities = 271/499 (54%), Positives = 363/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V I L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPRSITLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K YP+L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>ref|NP_001080792.1| inosine 5'-phosphate dehydrogenase 1 [Xenopus laevis]
gb|AAH46868.1| Impdh1-prov protein [Xenopus laevis]
Length = 514
Score = 548 bits (1411), Expect = e-154, Method: Composition-based stats.
Identities = 273/499 (54%), Positives = 363/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ +GL++NDF+ILPGFIDF + +V+++ T+ I L P++SSPMDTVTE
Sbjct: 16 DGLTAQQLFANSEGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPMISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
S MA AMALMGGIG+IH+NCT E QA VR VK + GFI P +S + V + K+
Sbjct: 76 SDMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSLNHTVGDVFEAKN 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI VTE GK KL+GIV ++DIDF+ KD S +S+ MT+RE++ V + L+
Sbjct: 136 RHGFSGIPVTETGKMGSKLVGIVTSRDIDFLTEKDYSTYLSEVMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDCRKQLLCGAAIGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+DV+VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAKNLID
Sbjct: 256 DKYRLDLLMQAGVDVVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP VADGG++ VG V K
Sbjct: 316 AGVDALRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVVADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSTSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ +RT+
Sbjct: 436 KVKVAQGVSGSIQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKLEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 496 SAQVEGGVHGLHSYEKRLY 514
>gb|EAW83652.1| IMP (inosine monophosphate) dehydrogenase 1, isoform CRA_d [Homo
sapiens]
Length = 522
Score = 548 bits (1411), Expect = e-154, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 359/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 24 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 83
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 84 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 143
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 144 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 203
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 204 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 263
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 264 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 323
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 324 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 383
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 384 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 443
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 444 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 503
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 504 SAQIEGGVHGLHSYEKRLY 522
>ref|XP_001110855.1| PREDICTED: inosine monophosphate dehydrogenase 2 isoform 6 [Macaca
mulatta]
Length = 514
Score = 548 bits (1411), Expect = e-154, Method: Composition-based stats.
Identities = 271/499 (54%), Positives = 364/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V I L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCLLEEIMTKREDLVVAPAGITLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP+L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>ref|NP_000875.2| inosine monophosphate dehydrogenase 2 [Homo sapiens]
sp|P12268|IMDH2_HUMAN Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2)
(IMPDH-II) (IMPD 2)
pdb|1B3O|A Chain A, Ternary Complex Of Human Type-Ii Inosine Monophosphate
Dehydrogenase With 6-Cl-Imp And Selenazole Adenine
Dinucleotide
pdb|1B3O|B Chain B, Ternary Complex Of Human Type-Ii Inosine Monophosphate
Dehydrogenase With 6-Cl-Imp And Selenazole Adenine
Dinucleotide
pdb|1NF7|A Chain A, Ternary Complex Of The Human Type Ii Inosine Monophosphate
Dedhydrogenase With Ribavirin Monophosphate And C2-
Mycophenolic Adenine Dinucleotide
pdb|1NF7|B Chain B, Ternary Complex Of The Human Type Ii Inosine Monophosphate
Dedhydrogenase With Ribavirin Monophosphate And C2-
Mycophenolic Adenine Dinucleotide
pdb|1NFB|A Chain A, Ternary Complex Of The Human Type Ii Inosine Monophosphate
Dedhydrogenase With 6cl-Imp And Nad
pdb|1NFB|B Chain B, Ternary Complex Of The Human Type Ii Inosine Monophosphate
Dedhydrogenase With 6cl-Imp And Nad
gb|AAA67054.1| inosine monophosphate dehydrogenase type II
gb|AAB70699.1| inosine monophosphate dehydrogenase type II [Homo sapiens]
gb|AAH06124.1| IMP (inosine monophosphate) dehydrogenase 2 [Homo sapiens]
gb|AAH12840.1| IMP (inosine monophosphate) dehydrogenase 2 [Homo sapiens]
gb|AAH15567.1| IMP (inosine monophosphate) dehydrogenase 2 [Homo sapiens]
gb|ABM84329.1| IMP (inosine monophosphate) dehydrogenase 2 [synthetic construct]
gb|ABM87720.1| IMP (inosine monophosphate) dehydrogenase 2 [synthetic construct]
Length = 514
Score = 547 bits (1410), Expect = e-154, Method: Composition-based stats.
Identities = 271/499 (54%), Positives = 363/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V I L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K YP+L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>gb|EDL13789.1| inosine 5'-phosphate dehydrogenase 1, isoform CRA_b [Mus musculus]
Length = 607
Score = 547 bits (1409), Expect = e-154, Method: Composition-based stats.
Identities = 268/499 (53%), Positives = 360/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 109 DGLTAQQLFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 168
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 169 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKI 228
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
+ G SGI +T G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 229 QHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRVELVVAPAGVTLK 288
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 289 EANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRED 348
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 349 DKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 408
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 409 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVK 468
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 469 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 528
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 529 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRTM 588
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 589 SAQIEGGVHGLHSYEKRLY 607
>emb|CAQ13978.1| IMP (inosine monophosphate) dehydrogenase 2 [Danio rerio]
Length = 514
Score = 546 bits (1408), Expect = e-153, Method: Composition-based stats.
Identities = 268/499 (53%), Positives = 368/499 (73%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG T ++LF S DGL++NDF+ILPG+IDF + +V+++ TK I + PL+SSPMDTVTE
Sbjct: 16 DGLTGQQLFNSGDGLTYNDFLILPGYIDFTADQVDLTSALTKQITMKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
S MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP+ V + K+
Sbjct: 76 SGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKRYEQGFITDPVVMSPNERVRDVFQAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDAS--APVSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ G+L+GI+ ++DIDF+K++ P+S+ MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDNGQMGGRLVGIISSRDIDFLKESEHDLPLSEVMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N++ +V + +R D + RD+P +S D LLC AA T
Sbjct: 196 EANEILQRSKKGKLPIVNEEGCLVAIIARTDLKKNRDFPLASKDSRKQLLCGAAIGTHND 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP+++V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNVQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AGAD+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A TSE PGEYFF DG+RLK YRGMGS+DAM + S RY SE++
Sbjct: 376 ALALGASTVMMGSLLAATSEAPGEYFFSDGIRLKKYRGMGSLDAMDKNLGSQTRYFSESD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT+
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLLVGIQHSCQDIGAKSLTQLRAMMYSGELRFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQMEGGVHSLHSYEKRLF 514
>ref|NP_035959.2| inosine 5'-phosphate dehydrogenase 1 [Mus musculus]
gb|AAH53416.1| Inosine 5'-phosphate dehydrogenase 1 [Mus musculus]
dbj|BAE42272.1| unnamed protein product [Mus musculus]
gb|EDL13790.1| inosine 5'-phosphate dehydrogenase 1, isoform CRA_c [Mus musculus]
Length = 514
Score = 546 bits (1408), Expect = e-153, Method: Composition-based stats.
Identities = 268/499 (53%), Positives = 360/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 16 DGLTAQQLFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 76 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKI 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
+ G SGI +T G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 136 QHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRVELVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 196 EANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 436 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 496 SAQIEGGVHGLHSYEKRLY 514
>ref|XP_850933.1| PREDICTED: similar to inosine 5-phosphate dehydrogenase 2 isoform 2
[Canis familiaris]
Length = 514
Score = 546 bits (1408), Expect = e-153, Method: Composition-based stats.
Identities = 271/499 (54%), Positives = 363/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V I L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGITLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPTLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>ref|NP_001008066.1| IMP (inosine monophosphate) dehydrogenase 2 [Xenopus tropicalis]
gb|AAH80955.1| IMP (inosine monophosphate) dehydrogenase 2 [Xenopus tropicalis]
emb|CAJ83737.1| IMP (inosine monophosphate) dehydrogenase 2 [Xenopus tropicalis]
Length = 514
Score = 546 bits (1408), Expect = e-153, Method: Composition-based stats.
Identities = 273/499 (54%), Positives = 363/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF + DGL++NDF+ILPG+IDF + +V+++ TK I L P+VSSPMDTVTE
Sbjct: 16 DGLTAQQLFGAGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPMVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+SMA AMAL GGIG++H+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 ASMAIAMALTGGIGIMHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKHRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVK--DASAPVSQYMTRRENMTVERYPIKLE 189
G GI +TE GK KL GI+ ++DIDF+K + +S+ MTRRE++ V + L+
Sbjct: 136 RHGFCGIPITENGKMGSKLAGIISSRDIDFLKSEEHDLALSEIMTRREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNGNDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+D +VLDSSQGN+I+Q++ I+++K+ Y L+V+AGNVVT QAKNLID
Sbjct: 256 DKYRLDLLVQAGVDAVVLDSSQGNSIFQINMIKFIKEKYQDLQVIAGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AGAD+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNVSSQKRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT+
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFIPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++LF
Sbjct: 496 SAQVEGGVHGLHSYEKRLF 514
>gb|EDM15208.1| IMP (inosine monophosphate) dehydrogenase 1 (predicted), isoform
CRA_b [Rattus norvegicus]
Length = 514
Score = 546 bits (1407), Expect = e-153, Method: Composition-based stats.
Identities = 268/499 (53%), Positives = 360/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 16 DGLTAQQLFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 76 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKI 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
+ G SGI +T G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 136 QHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 196 EANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 436 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 496 SAQIEGGVHGLHSYEKRLY 514
>ref|XP_001494600.1| PREDICTED: similar to hCG2002013 [Equus caballus]
Length = 604
Score = 546 bits (1407), Expect = e-153, Method: Composition-based stats.
Identities = 271/499 (54%), Positives = 362/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 106 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 165
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 166 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVKDVFEAKA 225
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V I L+
Sbjct: 226 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGITLK 285
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 286 EANEILQRSKKGKLPIVNKDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 345
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT QAKNLID
Sbjct: 346 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQAKNLID 405
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 406 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 465
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 466 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 525
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 526 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 585
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 586 SAQVEGGVHSLHSYEKRLF 604
>ref|NP_001029588.1| IMP (inosine monophosphate) dehydrogenase 2 [Bos taurus]
sp|Q3SWY3|IMDH2_BOVIN Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2)
(IMPDH-II) (IMPD 2)
gb|AAI04603.1| IMP (inosine monophosphate) dehydrogenase 2 [Bos taurus]
Length = 514
Score = 545 bits (1405), Expect = e-153, Method: Composition-based stats.
Identities = 271/499 (54%), Positives = 362/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPRDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ L+GI+ ++DIDF+K+ + + MT+RE++ V I L+
Sbjct: 136 RHGFCGIPITDTGRMGSHLVGIISSRDIDFLKEEEHDRLLGEIMTKREDLVVAPAGITLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ LS+AG+DV+VLDSSQGN+I+Q++ I+++K+ YP ++V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLSQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSIQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>pdb|1JCN|A Chain A, Binary Complex Of Human Type-I Inosine Monophosphate
Dehydrogenase With 6-Cl-Imp
pdb|1JCN|B Chain B, Binary Complex Of Human Type-I Inosine Monophosphate
Dehydrogenase With 6-Cl-Imp
Length = 514
Score = 545 bits (1405), Expect = e-153, Method: Composition-based stats.
Identities = 269/499 (53%), Positives = 358/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S D L++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 16 DGLTAQQLFASADDLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 76 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKNFEQGFITDPVVLSPSHTVGDVLEAKM 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 136 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 436 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 496 SAQIEGGVHGLHSYEKRLY 514
>ref|NP_035960.2| inosine 5'-phosphate dehydrogenase 2 [Mus musculus]
sp|P24547|IMDH2_MOUSE Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2)
(IMPDH-II) (IMPD 2)
gb|AAH10314.1| Inosine 5'-phosphate dehydrogenase 2 [Mus musculus]
gb|AAH52671.1| Inosine 5'-phosphate dehydrogenase 2 [Mus musculus]
dbj|BAE35879.1| unnamed protein product [Mus musculus]
dbj|BAE40908.1| unnamed protein product [Mus musculus]
dbj|BAE41367.1| unnamed protein product [Mus musculus]
dbj|BAE38929.1| unnamed protein product [Mus musculus]
dbj|BAE29791.1| unnamed protein product [Mus musculus]
dbj|BAE30225.1| unnamed protein product [Mus musculus]
dbj|BAE35402.1| unnamed protein product [Mus musculus]
dbj|BAE31422.1| unnamed protein product [Mus musculus]
gb|EDL21302.1| inosine 5'-phosphate dehydrogenase 2 [Mus musculus]
Length = 514
Score = 545 bits (1403), Expect = e-153, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 362/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>ref|NP_001083990.1| inosine 5'-phosphate dehydrogenase 2 [Xenopus laevis]
gb|AAH44122.1| Impdh2-prov protein [Xenopus laevis]
Length = 514
Score = 545 bits (1403), Expect = e-153, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 362/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG A++LF + DGL++NDF+ILPG+IDF + +V+++ TK I L P+VSSPMDTVTE
Sbjct: 16 DGLAAQQLFGAGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPMVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
++MA AMAL GGIG++H+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 ANMAIAMALTGGIGIMHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKHRVRHVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVK--DASAPVSQYMTRRENMTVERYPIKLE 189
G GI +TE GK KL GI+ ++DIDF++ + +S+ MT RE++ V + L+
Sbjct: 136 RHGFCGIPITENGKMGSKLAGIISSRDIDFLRPEEHDLALSEIMTLREDLVVALAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNGNDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+D +VLDSSQGN+I+Q++ I+++K+ YP L+V+AGNVVT QAKNLID
Sbjct: 256 DKYRLDLLVQAGVDAVVLDSSQGNSIFQINMIKYIKEKYPDLQVIAGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AGAD+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNVSSQKRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT+
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFIPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++LF
Sbjct: 496 SAQVEGGVHGLHSYEKRLF 514
>gb|AAA39311.1| IMP dehydrogenase (EC 1.2.1.14)
Length = 514
Score = 544 bits (1402), Expect = e-153, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 361/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMTYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>ref|XP_001478203.1| PREDICTED: similar to Inosine 5-phosphate dehydrogenase 2 [Mus
musculus]
Length = 514
Score = 544 bits (1402), Expect = e-153, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 361/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALAFGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>ref|NP_958872.1| inosine monophosphate dehydrogenase 2 [Danio rerio]
gb|AAH46905.1| IMP (inosine monophosphate) dehydrogenase 2 [Danio rerio]
Length = 514
Score = 544 bits (1402), Expect = e-153, Method: Composition-based stats.
Identities = 267/499 (53%), Positives = 367/499 (73%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG T ++LF S DGL++NDF+ILPG+IDF + +V+++ TK I + PL+SSPMDTVTE
Sbjct: 16 DGLTGQQLFNSGDGLTYNDFLILPGYIDFTADQVDLTSALTKQITMKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
S MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP+ V + K+
Sbjct: 76 SGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKRYEQGFITDPVVMSPNERVRDVFQAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDAS--APVSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ G+L+GI+ ++DIDF+K++ P+S+ MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDNGQMGGRLVGIISSRDIDFLKESEHDLPLSEVMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N++ +V + +R D + RD+P +S D LLC AA T
Sbjct: 196 EANEILQRSKKGKLPIVNEEGCLVAIIARTDLKKNRDFPLASKDSRKQLLCGAAIGTHND 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP+++V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNVQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AGAD+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A TSE PGEYFF DG+RLK YRGMGS+DAM + S RY SE++
Sbjct: 376 ALALGASTVMMGSLLAATSEAPGEYFFSDGIRLKKYRGMGSLDAMDKNLGSQTRYFSESD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT+
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLLVGIQHSCQDIGAKSLTQLRAMMYSGELRFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHS H YE++LF
Sbjct: 496 SAQMEGGVHSQHSYEKRLF 514
>ref|XP_001367707.1| PREDICTED: similar to hCG2002013, [Monodelphis domestica]
Length = 514
Score = 544 bits (1402), Expect = e-153, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 362/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ GK +L+GI+ ++DIDF+K+ + + MTRRE++ V + L+
Sbjct: 136 RHGFCGIPITDNGKMGSRLVGIISSRDIDFLKEEEHDRFLDEIMTRREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDTKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ Y +L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYNNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNLGSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++LF
Sbjct: 496 SAQVEGGVHGLHSYEKRLF 514
>sp|P12269|IMDH2_CRIGR Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2)
(IMPDH-II) (IMPD 2)
pir||B31997 IMP dehydrogenase (EC 1.1.1.205) - Chinese hamster
pdb|1JR1|A Chain A, Crystal Structure Of Inosine Monophosphate Dehydrogenase
In Complex With Mycophenolic Acid
pdb|1JR1|B Chain B, Crystal Structure Of Inosine Monophosphate Dehydrogenase
In Complex With Mycophenolic Acid
gb|AAA36993.1| inosine-5'-monophosphate dehydrogenase
Length = 514
Score = 544 bits (1402), Expect = e-153, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 362/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V I L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGITLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP+L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYMKEKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGCGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>dbj|BAE25403.1| unnamed protein product [Mus musculus]
Length = 514
Score = 544 bits (1401), Expect = e-153, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 362/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNEYDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>ref|XP_001372080.1| PREDICTED: similar to Inosine monophosphate dehydrogenase 1
[Monodelphis domestica]
Length = 575
Score = 543 bits (1400), Expect = e-153, Method: Composition-based stats.
Identities = 269/499 (53%), Positives = 358/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 77 DGLTAQQLFAIADGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVTE 136
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 137 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKM 196
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R ++ V + L+
Sbjct: 197 RHGFSGIPITETGAMGSKLVGIVTSRDIDFLAEKDHATYLSEVMTGRNDLVVAPAGVTLK 256
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 257 EANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDAHKQLLCGAAVGTRED 316
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K YP L+V+ GNVVT QAKNLID
Sbjct: 317 DKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKHKYPQLQVIGGNVVTAAQAKNLID 376
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 377 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVK 436
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 437 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 496
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 497 KVKVAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 556
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 557 SAQIEGGVHGLHSYEKRLY 575
>sp|P50096|IMDH1_MOUSE Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1)
(IMPDH-I) (IMPD 1)
gb|AAA18285.1| type I inosine monophosphate dehydrogenase
Length = 514
Score = 543 bits (1400), Expect = e-152, Method: Composition-based stats.
Identities = 267/499 (53%), Positives = 358/499 (71%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA ELF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 16 DGLTAHELFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 76 ADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKI 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
+ G SGI +T G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 136 QHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRVELVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 196 EANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG DV+V DSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQAGADVIVHDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRG+GS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGIGSLDAMEKSSSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 436 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 496 SAQIEGGVHGLHSYEKRLY 514
>gb|EAW83649.1| IMP (inosine monophosphate) dehydrogenase 1, isoform CRA_a [Homo
sapiens]
Length = 561
Score = 543 bits (1398), Expect = e-152, Method: Composition-based stats.
Identities = 269/499 (53%), Positives = 358/499 (71%), Gaps = 5/499 (1%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF S DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE
Sbjct: 65 DGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTE 124
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMALMGGIG IH+NCT E QA VR K + GFI P +SP V + K
Sbjct: 125 ADMAIAMALMGGIGFIHHNCTPEFQANEVR--KKFEQGFITDPVVLSPSHTVGDVLEAKM 182
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFV--KDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE G KL+GIV ++DIDF+ KD + +S+ MT R + V + L+
Sbjct: 183 RHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLK 242
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 243 EANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRED 302
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLID
Sbjct: 303 DKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLID 362
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V K
Sbjct: 363 AGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVK 422
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 423 ALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGD 482
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
+++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 483 KVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTM 542
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++L+
Sbjct: 543 SAQIEGGVHGLHSYEKRLY 561
>gb|AAA20181.1| IMP dehydrogenase
Length = 514
Score = 542 bits (1397), Expect = e-152, Method: Composition-based stats.
Identities = 269/499 (53%), Positives = 360/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICI QEVLACGRPQATA+YKV YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICIIQEVLACGRPQATAVYKVYEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>dbj|BAE30628.1| unnamed protein product [Mus musculus]
Length = 514
Score = 542 bits (1396), Expect = e-152, Method: Composition-based stats.
Identities = 270/499 (54%), Positives = 361/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAP--VSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ +L+GI+ ++DIDF+K+ + + MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L+ AG+DV+VLDSSQGN+I Q++ I+++K+ YP L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLALAGVDVVVLDSSQGNSISQINMIKYIKEKYPSLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQVEGGVHSLHSYEKRLF 514
>ref|XP_001641875.1| predicted protein [Nematostella vectensis]
gb|EDO49812.1| predicted protein [Nematostella vectensis]
Length = 514
Score = 541 bits (1395), Expect = e-152, Method: Composition-based stats.
Identities = 269/498 (54%), Positives = 360/498 (72%), Gaps = 2/498 (0%)
Query: 13 DGTTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTES 72
DG TA +LF DGL+++DFIILPGFIDF ++ V+++ T+ I + PLVSSPMDTVTES
Sbjct: 17 DGMTAGQLFQSDGLTYSDFIILPGFIDFPATDVDLTSPLTRRITIKTPLVSSPMDTVTES 76
Query: 73 SMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSE 132
++A AMAL GGIG+IH+NC++E QA +R VK + GFIM P +S V+ + + K
Sbjct: 77 ALATAMALNGGIGIIHHNCSIEFQANEIRKVKKFEQGFIMAPLVLSATNTVADVIDAKQR 136
Query: 133 KGISGILVTEGGKYDGKLLGIVCTKDIDFVK--DASAPVSQYMTRRENMTVERYPIKLEE 190
G SGI +TE G+ G L GIV ++DIDF+ + + + MTR E++ V + I L E
Sbjct: 137 HGFSGIPITENGQLGGILQGIVTSRDIDFLHGVENHKQLGEVMTRLEDLVVAKAGITLNE 196
Query: 191 AMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREAD 250
A +L S+ G LP++N+K E+V L +R D + RDYP +S D N LL AA TRE D
Sbjct: 197 ANKILQMSKKGKLPIVNEKGELVSLIARTDLKKNRDYPLASKDENKQLLVGAAIGTREDD 256
Query: 251 KGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDA 310
K R+ AL EAG+DV+V+DSSQGN+IYQ+S I +K+ YP+L++V GNVVT QAKNLIDA
Sbjct: 257 KARLHALVEAGVDVVVIDSSQGNSIYQLSLISHIKENYPNLQIVGGNVVTASQAKNLIDA 316
Query: 311 GADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKA 370
G D+LR+GMGSGSICITQEV+A GRPQ TA+YKVA YA GVP +ADGG++NVG + KA
Sbjct: 317 GVDALRVGMGSGSICITQEVMAVGRPQGTAVYKVAEYARRFGVPVLADGGIQNVGHITKA 376
Query: 371 LAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENET 430
L++GA+ M+GS++AGTSE PGEYFF DG+RLK YRGMGS+ AM + S RY SEN+
Sbjct: 377 LSLGASTVMMGSLLAGTSEAPGEYFFADGVRLKKYRGMGSLSAMEKNSSSASRYFSENDK 436
Query: 431 LQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLT 490
++VAQGV+G+V+DKGS+ K + Y+ G+Q QD+G S ++R +Y G++ F RRT +
Sbjct: 437 VKVAQGVSGSVVDKGSIHKFVPYLTAGIQHGCQDLGAKSLTSLRSMMYSGELKFERRTTS 496
Query: 491 AQSEGAVHSLHHYERKLF 508
+Q EG VH LH YE++LF
Sbjct: 497 SQIEGGVHGLHSYEKRLF 514
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|XP_001252299.1| PREDICTED: inosine monophosphate dehydr... 886 0.0
ref|NP_000874.2| inosine monophosphate dehydrogenase 1 isof... 879 0.0
ref|NP_899066.1| inosine monophosphate dehydrogenase 1 isof... 879 0.0
ref|NP_001096075.1| inosine monophosphate dehydrogenase 1 i... 878 0.0
ref|NP_001071309.1| inosine monophosphate dehydrogenase 1 [... 878 0.0
gb|EDL13789.1| inosine 5'-phosphate dehydrogenase 1, isofor... 877 0.0
sp|P20839|IMDH1_HUMAN Inosine-5'-monophosphate dehydrogenas... 876 0.0
gb|EAW83652.1| IMP (inosine monophosphate) dehydrogenase 1,... 876 0.0
emb|CAK04261.1| novel protein similar to vertebrate IMP (in... 875 0.0
pdb|1JCN|A Chain A, Binary Complex Of Human Type-I Inosine ... 871 0.0
ref|NP_001080792.1| inosine 5'-phosphate dehydrogenase 1 [X... 870 0.0
gb|EAW83649.1| IMP (inosine monophosphate) dehydrogenase 1,... 869 0.0
ref|NP_001017283.1| IMP (inosine monophosphate) dehydrogena... 869 0.0
ref|NP_035959.2| inosine 5'-phosphate dehydrogenase 1 [Mus ... 869 0.0
gb|EDM15208.1| IMP (inosine monophosphate) dehydrogenase 1 ... 869 0.0
ref|XP_001372080.1| PREDICTED: similar to Inosine monophosp... 869 0.0
gb|EAW64946.1| hCG2002013, isoform CRA_a [Homo sapiens] 869 0.0
ref|NP_001025772.1| inosine monophosphate dehydrogenase 2 [... 868 0.0
ref|XP_001494600.1| PREDICTED: similar to hCG2002013 [Equus... 868 0.0
emb|CAI21140.1| novel protein similar to vertebrate IMP (in... 867 0.0
ref|XP_001110855.1| PREDICTED: inosine monophosphate dehydr... 866 0.0
ref|NP_001002177.1| hypothetical protein LOC431724 [Danio r... 866 0.0
ref|NP_001014391.1| hypothetical protein LOC338306 [Danio r... 865 0.0
ref|XP_850933.1| PREDICTED: similar to inosine 5-phosphate ... 864 0.0
ref|NP_000875.2| inosine monophosphate dehydrogenase 2 [Hom... 864 0.0
ref|XP_001367707.1| PREDICTED: similar to hCG2002013, [Mono... 863 0.0
ref|NP_035960.2| inosine 5'-phosphate dehydrogenase 2 [Mus ... 863 0.0
sp|P12269|IMDH2_CRIGR Inosine-5'-monophosphate dehydrogenas... 863 0.0
ref|NP_001029588.1| IMP (inosine monophosphate) dehydrogena... 863 0.0
sp|P50096|IMDH1_MOUSE Inosine-5'-monophosphate dehydrogenas... 863 0.0
gb|AAA36114.1| IMP dehydrogenase type 1 (EC 1.1.1.205) 862 0.0
gb|AAA39311.1| IMP dehydrogenase (EC 1.2.1.14) 861 0.0
ref|XP_001478203.1| PREDICTED: similar to Inosine 5-phospha... 861 0.0
gb|AAA36112.1| inosine-5'-monophosphate dehydrogenase (EC 1... 861 0.0
dbj|BAE30628.1| unnamed protein product [Mus musculus] 861 0.0
ref|NP_001082410.1| similar to inosine 5'-phosphate dehydro... 860 0.0
dbj|BAE25403.1| unnamed protein product [Mus musculus] 860 0.0
emb|CAQ13978.1| IMP (inosine monophosphate) dehydrogenase 2... 860 0.0
ref|XP_516452.2| PREDICTED: inosine monophosphate dehydroge... 860 0.0
ref|XP_862835.1| PREDICTED: similar to Inosine-5-monophosph... 859 0.0
gb|AAA20181.1| IMP dehydrogenase 859 0.0
ref|NP_954530.1| inosine monophosphate dehydrogenase 2 [Rat... 858 0.0
ref|NP_958872.1| inosine monophosphate dehydrogenase 2 [Dan... 858 0.0
ref|XP_862898.1| PREDICTED: similar to Inosine-5-monophosph... 856 0.0
ref|XP_533835.2| PREDICTED: similar to inosine 5-phosphate ... 856 0.0
ref|XP_862874.1| PREDICTED: similar to Inosine-5-monophosph... 856 0.0
ref|NP_001008066.1| IMP (inosine monophosphate) dehydrogena... 854 0.0
ref|XP_001505397.1| PREDICTED: similar to hCG2002013 [Ornit... 854 0.0
ref|XP_001089341.1| PREDICTED: similar to inosine monophosp... 852 0.0
ref|YP_001665693.1| response regulator receiver protein [Th... 852 0.0
ref|NP_001083990.1| inosine 5'-phosphate dehydrogenase 2 [X... 851 0.0
ref|YP_001180491.1| inosine-5'-monophosphate dehydrogenase ... 851 0.0
ref|NP_622249.1| IMP dehydrogenase/GMP reductase [Thermoana... 851 0.0
ref|XP_001110813.1| PREDICTED: inosine monophosphate dehydr... 850 0.0
dbj|BAD18464.1| unnamed protein product [Homo sapiens] 850 0.0
ref|XP_001501637.1| PREDICTED: hypothetical protein [Equus ... 849 0.0
ref|XP_850999.1| PREDICTED: similar to inosine monophosphat... 849 0.0
ref|XP_862810.1| PREDICTED: similar to inosine 5-phosphate ... 849 0.0
emb|CAI45968.1| hypothetical protein [Homo sapiens] 846 0.0
emb|CAG03265.1| unnamed protein product [Tetraodon nigrovir... 846 0.0
ref|ZP_01667581.1| inosine-5'-monophosphate dehydrogenase [... 843 0.0
ref|ZP_02914844.1| inosine-5'-monophosphate dehydrogenase [... 840 0.0
ref|NP_013656.1| Inosine monophosphate dehydrogenase, catal... 838 0.0
ref|XP_001641875.1| predicted protein [Nematostella vectens... 838 0.0
ref|YP_360021.1| inosine-5'-monophosphate dehydrogenase [Ca... 838 0.0
ref|YP_145862.1| inositol-5-monophosphate dehydrogenase [Ge... 837 0.0
gb|EDN64340.1| IMP dehydrogenase [Saccharomyces cerevisiae ... 836 0.0
gb|EDL13788.1| inosine 5'-phosphate dehydrogenase 1, isofor... 835 0.0
ref|NP_001102089.1| inosine 5'-phosphate dehydrogenase 1 [R... 835 0.0
emb|CAA39204.1| IMP dehydrogenase [Bacillus subtilis] 835 0.0
ref|YP_076743.1| inosine-5'-monophosphate dehydrogenase [Sy... 834 0.0
ref|NP_984977.1| AER117Wp [Ashbya gossypii ATCC 10895] >gi|... 834 0.0
ref|XP_309514.2| AGAP011133-PA [Anopheles gambiae str. PEST... 833 0.0
ref|YP_001124141.1| inositol-5-monophosphate dehydrogenase ... 833 0.0
ref|NP_240886.1| inositol-5-monophosphate dehydrogenase [Ba... 831 0.0
ref|NP_387890.1| inositol-5-monophosphate dehydrogenase [Ba... 830 0.0
ref|YP_545250.1| inosine-5'-monophosphate dehydrogenase [Me... 829 0.0
ref|YP_001695789.1| Inosine-5'-monophosphate dehydrogenase ... 829 0.0
sp|O00086|IMDH3_CANAL Probable inosine-5'-monophosphate deh... 828 0.0
ref|XP_001653775.1| inosine-5-monophosphate dehydrogenase [... 828 0.0
ref|YP_001419688.1| GuaB [Bacillus amyloliquefaciens FZB42]... 827 0.0
ref|XP_623071.1| PREDICTED: similar to Inosine-5-monophosph... 827 0.0
ref|ZP_01725067.1| inositol-5-monophosphate dehydrogenase [... 826 0.0
gb|AAW65379.1| mycophenolic acid-resistant inosine-5'-monop... 826 0.0
ref|NP_214389.1| inosine monophosphate dehydrogenase [Aquif... 825 0.0
ref|XP_460442.1| hypothetical protein DEHA0F02068g [Debaryo... 824 0.0
ref|ZP_01967358.1| hypothetical protein RUMTOR_00905 [Rumin... 824 0.0
ref|ZP_02234042.1| hypothetical protein DORFOR_00900 [Dorea... 824 0.0
ref|XP_001861658.1| inosine-5'-monophosphate dehydrogenase ... 823 0.0
gb|AAF70813.1|AF249293_1 putative inosine 5-monophosphate d... 823 0.0
ref|YP_002769495.1| inosine-5'-monophosphate dehydrogenase ... 823 0.0
ref|ZP_02039215.1| hypothetical protein BACCAP_04867 [Bacte... 822 0.0
ref|XP_451781.1| unnamed protein product [Kluyveromyces lac... 822 0.0
ref|ZP_02079836.1| hypothetical protein CLOLEP_01281 [Clost... 822 0.0
ref|XP_001483272.1| hypothetical protein PGUG_04001 [Pichia... 821 0.0
ref|NP_349307.1| inositol-5-monophosphate dehydrogenase [Cl... 821 0.0
gb|AAW65380.1| inosine-5'-monophosphate dehydrogenase [Cand... 821 0.0
ref|YP_173515.1| inositol-5-monophosphate dehydrogenase [Ba... 821 0.0
ref|XP_001384903.1| hypothetical protein PICST_65804 [Pichi... 821 0.0
ref|YP_001512091.1| inosine-5'-monophosphate dehydrogenase ... 820 0.0
ref|YP_001373379.1| inosine-5'-monophosphate dehydrogenase ... 819 0.0
ref|ZP_02206927.1| hypothetical protein COPEUT_01719 [Copro... 819 0.0
ref|ZP_02862590.1| hypothetical protein ANASTE_01809 [Anaer... 819 0.0
ref|YP_001680969.1| inosine-5'-monophosphate dehydrogenase ... 819 0.0
dbj|BAA89464.1| IMPDH [Bacillus cereus] 819 0.0
ref|YP_077291.1| inosine-monophosphate dehydrogenase [Bacil... 819 0.0
gb|EDN62491.1| IMP dehydrogenase [Saccharomyces cerevisiae ... 819 0.0
ref|NP_782942.1| inositol-5-monophosphate dehydrogenase [Cl... 819 0.0
ref|ZP_02356071.1| inositol-5-monophosphate dehydrogenase [... 818 0.0
ref|NP_976337.1| inositol-5-monophosphate dehydrogenase [Ba... 818 0.0
ref|ZP_01552004.1| IMP dehydrogenase [Methylophilales bacte... 818 0.0
dbj|BAA88235.1| IMP dehydrogenase [Bacillus cereus] 817 0.0
ref|XP_448685.1| unnamed protein product [Candida glabrata]... 817 0.0
ref|YP_001717214.1| inosine-5'-monophosphate dehydrogenase ... 817 0.0
ref|ZP_01995666.1| hypothetical protein DORLON_01661 [Dorea... 817 0.0
ref|YP_034368.1| inositol-5-monophosphate dehydrogenase [Ba... 817 0.0
ref|ZP_02041332.1| hypothetical protein RUMGNA_02099 [Rumin... 817 0.0
ref|NP_900973.1| inositol-5-monophosphate dehydrogenase [Ch... 817 0.0
ref|NP_829917.1| inositol-5-monophosphate dehydrogenase [Ba... 816 0.0
ref|ZP_01190168.1| IMP dehydrogenase [Halothermothrix oreni... 816 0.0
gb|AAN87502.1| Inosine-5'-monophosphate dehydrogenase [Heli... 816 0.0
ref|ZP_02429849.1| hypothetical protein CLOSCI_00052 [Clost... 816 0.0
ref|ZP_01173811.1| inositol-5-monophosphate dehydrogenase [... 816 0.0
ref|NP_842579.1| inositol-5-monophosphate dehydrogenase [Ba... 816 0.0
ref|ZP_02089056.1| hypothetical protein CLOBOL_06625 [Clost... 816 0.0
ref|ZP_00946937.1| Inosine-5'-monophosphate dehydrogenase [... 816 0.0
ref|ZP_01963621.1| hypothetical protein RUMOBE_01343 [Rumin... 816 0.0
ref|NP_519550.1| inositol-5-monophosphate dehydrogenase [Ra... 816 0.0
gb|EEK04434.1| inosine-5'-monophosphate dehydrogenase [Alic... 815 0.0
ref|YP_429965.1| inosine-5'-monophosphate dehydrogenase [Mo... 815 0.0
ref|ZP_00743847.1| Inosine-5'-monophosphate dehydrogenase [... 814 0.0
ref|ZP_00390434.1| COG0516: IMP dehydrogenase/GMP reductase... 814 0.0
ref|YP_001485759.1| IMP dehydrogenase [Bacillus pumilus SAF... 814 0.0
ref|YP_001642905.1| inosine-5'-monophosphate dehydrogenase ... 814 0.0
ref|XP_966518.1| PREDICTED: similar to Inosine-5-monophosph... 814 0.0
ref|XP_001085281.1| PREDICTED: inosine monophosphate dehydr... 814 0.0
ref|ZP_02093569.1| hypothetical protein PEPMIC_00320 [Pepto... 814 0.0
ref|YP_001857542.1| inosine-5'-monophosphate dehydrogenase ... 814 0.0
ref|YP_436057.1| inosine-5'-monophosphate dehydrogenase [Ha... 814 0.0
ref|YP_001211868.1| hypothetical protein PTH_1318 [Pelotoma... 814 0.0
ref|ZP_02850469.1| inosine-5'-monophosphate dehydrogenase [... 813 0.0
ref|ZP_02074678.1| hypothetical protein CLOL250_01453 [Clos... 813 0.0
ref|ZP_02263522.1| inositol-5-monophosphate dehydrogenase [... 813 0.0
ref|NP_012088.1| Inosine monophosphate dehydrogenase, catal... 813 0.0
gb|ACB54657.1| inosine 5' monophosphate dehydrogenase [Paen... 813 0.0
ref|YP_878931.1| inositol-5-monophosphate dehydrogenase [Cl... 813 0.0
ref|ZP_02438314.1| hypothetical protein CLOSS21_00765 [Clos... 812 0.0
ref|XP_001641935.1| predicted protein [Nematostella vectens... 812 0.0
ref|NP_727441.1| raspberry CG1799-PA, isoform A [Drosophila... 812 0.0
ref|ZP_02950650.1| inosine-5'-monophosphate dehydrogenase [... 812 0.0
ref|ZP_02379271.1| inositol-5-monophosphate dehydrogenase [... 811 0.0
ref|YP_001560380.1| inosine-5'-monophosphate dehydrogenase ... 811 0.0
ref|ZP_02025103.1| hypothetical protein EUBVEN_00328 [Eubac... 811 0.0
ref|YP_001318789.1| inosine-5'-monophosphate dehydrogenase ... 811 0.0
ref|ZP_01516974.1| inosine-5'-monophosphate dehydrogenase [... 811 0.0
ref|YP_001919809.1| inosine-5'-monophosphate dehydrogenase ... 811 0.0
ref|NP_013536.1| Inosine monophosphate dehydrogenase, catal... 811 0.0
ref|YP_001898882.1| inosine-5'-monophosphate dehydrogenase ... 810 0.0
ref|ZP_02008991.1| inosine-5'-monophosphate dehydrogenase [... 810 0.0
ref|YP_001113252.1| inosine-5'-monophosphate dehydrogenase ... 810 0.0
ref|YP_001884623.1| inosine-5'-monophosphate dehydrogenase ... 810 0.0
ref|YP_001250469.1| inosine-5'-monophosphate dehydrogenase ... 810 0.0
ref|YP_095750.1| inosine-5'-monophosphate dehydrogenase [Le... 809 0.0
ref|ZP_02177021.1| inosine monophosphate dehydrogenase [Hyd... 809 0.0
gb|EAW83650.1| IMP (inosine monophosphate) dehydrogenase 1,... 809 0.0
dbj|BAB70780.1| unnamed protein product [Homo sapiens] 809 0.0
ref|XP_001749943.1| predicted protein [Monosiga brevicollis... 809 0.0
ref|YP_296065.1| inositol-5-monophosphate dehydrogenase [Ra... 809 0.0
ref|YP_001188966.1| inositol-5-monophosphate dehydrogenase ... 809 0.0
ref|ZP_00979930.1| COG0516: IMP dehydrogenase/GMP reductase... 809 0.0
gb|EEH96603.1| inositol-monophosphate dehydrogenase [Clostr... 809 0.0
ref|XP_001355544.1| GA14756-PA [Drosophila pseudoobscura] >... 809 0.0
ref|YP_001797406.1| inosine-5'-monophosphate dehydrogenase ... 808 0.0
ref|YP_001599217.1| inosine-5'-monophosphate dehydrogenase ... 808 0.0
ref|ZP_02620682.2| inosine-5'-monophosphate dehydrogenase [... 808 0.0
ref|YP_127026.1| hypothetical protein lpl1687 [Legionella p... 808 0.0
ref|ZP_02993260.1| hypothetical protein CLOSPO_00303 [Clost... 808 0.0
ref|YP_001119735.1| inositol-5-monophosphate dehydrogenase ... 808 0.0
ref|YP_411895.1| inosine-5'-monophosphate dehydrogenase [Ni... 807 0.0
ref|NP_274226.1| inositol-5-monophosphate dehydrogenase [Ne... 807 0.0
ref|YP_975144.1| inositol-5-monophosphate dehydrogenase [Ne... 807 0.0
ref|YP_753603.1| IMP dehydrogenase [Syntrophomonas wolfei s... 807 0.0
ref|YP_726498.1| inositol-5-monophosphate dehydrogenase [Ra... 806 0.0
ref|YP_369539.1| inositol-5-monophosphate dehydrogenase [Bu... 806 0.0
gb|AAX77966.1| unknown protein [synthetic construct] 806 0.0
ref|XP_503115.1| hypothetical protein [Yarrowia lipolytica]... 806 0.0
ref|YP_001634245.1| inosine-5'-monophosphate dehydrogenase ... 806 0.0
ref|ZP_02910335.1| inosine-5'-monophosphate dehydrogenase [... 805 0.0
ref|ZP_01739391.1| inosine-5'-monophosphate dehydrogenase [... 805 0.0
ref|XP_001110769.1| PREDICTED: inosine monophosphate dehydr... 805 0.0
ref|NP_284115.1| inositol-5-monophosphate dehydrogenase [Ne... 805 0.0
ref|ZP_01862180.1| inositol-5-monophosphate dehydrogenase [... 805 0.0
ref|YP_001392641.1| inosine-5'-monophosphate dehydrogenase ... 805 0.0
ref|YP_170270.1| Inosine-5-monophosphate dehydrogenase [Fra... 805 0.0
ref|ZP_02002658.1| Inosine-5'-monophosphate dehydrogenase [... 804 0.0
ref|YP_971702.1| inosine-5'-monophosphate dehydrogenase [Ac... 804 0.0
ref|YP_001255780.1| inositol-5-monophosphate dehydrogenase ... 804 0.0
ref|ZP_03906688.1| inosine-5'-monophosphate dehydrogenase [... 804 0.0
ref|YP_001782919.1| inosine-5'-monophosphate dehydrogenase ... 804 0.0
ref|YP_526933.1| IMP dehydrogenase [Saccharophagus degradan... 804 0.0
ref|YP_583613.1| inositol-5-monophosphate dehydrogenase [Ra... 804 0.0
ref|YP_773914.1| inositol-5-monophosphate dehydrogenase [Bu... 804 0.0
ref|YP_001765294.1| inosine-5'-monophosphate dehydrogenase ... 804 0.0
ref|XP_001483486.1| hypothetical protein PGUG_04215 [Pichia... 803 0.0
ref|YP_001409640.1| inosine-5'-monophosphate dehydrogenase ... 803 0.0
ref|ZP_03854594.1| inosine-5'-monophosphate dehydrogenase [... 803 0.0
ref|YP_108726.1| inositol-5-monophosphate dehydrogenase [Bu... 803 0.0
ref|YP_001788612.1| inosine-5'-monophosphate dehydrogenase ... 802 0.0
emb|CAO86108.1| inosine-5'-monophosphate dehydrogenase [Clo... 802 0.0
ref|ZP_01892873.1| inosine-5'-monophosphate dehydrogenase [... 802 0.0
ref|ZP_01115483.1| inositol-5-monophosphate dehydrogenase [... 802 0.0
ref|XP_975808.1| PREDICTED: similar to Inosine-5-monophosph... 802 0.0
ref|YP_001891952.1| IMP dehydrogenase/GMP reductase [Franci... 801 0.0
ref|YP_514129.1| Inosine-5-monophosphate dehydrogenase [Fra... 801 0.0
gb|EEJ80041.1| inosine-5'-monophosphate dehydrogenase [Kang... 801 0.0
ref|ZP_02841449.1| inosine-5'-monophosphate dehydrogenase [... 800 0.0
ref|ZP_01043759.1| inositol-5-monophosphate dehydrogenase [... 800 0.0
ref|XP_001110506.1| PREDICTED: inosine monophosphate dehydr... 800 0.0
ref|YP_001676882.1| Malate dehydrogenase [Francisella philo... 800 0.0
ref|ZP_02691687.1| inosine-5'-monophosphate dehydrogenase [... 800 0.0
ref|YP_442580.1| inositol-5-monophosphate dehydrogenase [Bu... 799 0.0
ref|NP_229148.1| inosine-5'-monophosphate dehydrogenase [Th... 799 0.0
ref|YP_001875186.1| inosine-5'-monophosphate dehydrogenase ... 799 0.0
ref|YP_001930992.1| inosine-5'-monophosphate dehydrogenase ... 799 0.0
ref|XP_862783.1| PREDICTED: similar to inosine 5-phosphate ... 799 0.0
ref|ZP_02883330.1| inosine-5'-monophosphate dehydrogenase [... 799 0.0
ref|YP_207925.1| inositol-5-monophosphate dehydrogenase [Ne... 799 0.0
ref|YP_559301.1| inositol-5-monophosphate dehydrogenase [Bu... 799 0.0
pdb|1VRD|A Chain A, Crystal Structure Of Inosine-5'-Monopho... 799 0.0
ref|ZP_03992373.1| IMP dehydrogenase [Oribacterium sinus F0... 799 0.0
ref|YP_958999.1| inosine-5'-monophosphate dehydrogenase [Ma... 799 0.0
ref|YP_001739509.1| inosine-5'-monophosphate dehydrogenase ... 798 0.0
ref|YP_001306807.1| inosine-5'-monophosphate dehydrogenase ... 798 0.0
ref|YP_001916216.1| inosine-5'-monophosphate dehydrogenase ... 797 0.0
ref|YP_001896051.1| inosine-5'-monophosphate dehydrogenase ... 797 0.0
ref|XP_566768.1| IMP dehydrogenase [Cryptococcus neoformans... 797 0.0
ref|XP_001527068.1| inosine-5'-monophosphate dehydrogenase ... 797 0.0
ref|ZP_02468286.1| inositol-5-monophosphate dehydrogenase [... 796 0.0
ref|YP_001430358.1| inosine-5'-monophosphate dehydrogenase ... 796 0.0
ref|ZP_04009332.1| inositol-5-monophosphate dehydrogenase [... 795 0.0
ref|YP_342662.1| IMP dehydrogenase [Nitrosococcus oceani AT... 795 0.0
ref|NP_953244.1| inosine-5'-monophosphate dehydrogenase [Ge... 795 0.0
ref|XP_638973.1| IMP dehydrogenase [Dictyostelium discoideu... 795 0.0
ref|ZP_01112019.1| inositol-5-monophosphate dehydrogenase [... 795 0.0
ref|YP_741857.1| inosine-5'-monophosphate dehydrogenase [Al... 795 0.0
ref|YP_002796618.1| GuaB [Laribacter hongkongensis HLHK9] >... 795 0.0
ref|ZP_02211058.1| hypothetical protein CLOBAR_00656 [Clost... 795 0.0
ref|ZP_03980672.1| IMP dehydrogenase [Enterococcus faecium ... 794 0.0
ref|YP_523537.1| inosine-5'-monophosphate dehydrogenase [Rh... 794 0.0
ref|NP_595702.1| IMP dehydrogenase Gua1 (predicted) [Schizo... 793 0.0
ref|NP_840196.1| guaB; inosine-5'-monophosphate dehydrogena... 793 0.0
ref|YP_662680.1| inositol-5-monophosphate dehydrogenase [Ps... 793 0.0
ref|YP_569400.1| inositol-5-monophosphate dehydrogenase [Rh... 793 0.0
ref|ZP_00604372.1| IMP dehydrogenase [Enterococcus faecium ... 792 0.0
gb|EEJ84817.1| inosine-5'-monophosphate dehydrogenase [Meio... 792 0.0
ref|YP_001838659.1| Inosine-5'-monophosphate dehydrogenase ... 792 0.0
ref|XP_001879769.1| predicted protein [Laccaria bicolor S23... 792 0.0
ref|NP_765903.1| inositol-monophosphate dehydrogenase [Stap... 792 0.0
ref|YP_001543976.1| inosine-5'-monophosphate dehydrogenase ... 792 0.0
ref|XP_964976.1| inosine-5'-monophosphate dehydrogenase IMD... 792 0.0
ref|YP_001275063.1| inosine-5'-monophosphate dehydrogenase ... 792 0.0
ref|ZP_02444933.1| hypothetical protein ANACOL_04268 [Anaer... 792 0.0
ref|YP_001156201.1| inositol-5-monophosphate dehydrogenase ... 792 0.0
ref|YP_536339.1| inositol-5-monophosphate dehydrogenase [La... 791 0.0
ref|YP_112825.1| inosine-5'-monophosphate dehydrogenase [Me... 791 0.0
ref|XP_001834217.1| hypothetical protein CC1G_09717 [Coprin... 790 0.0
ref|ZP_02420021.1| hypothetical protein ANACAC_02623 [Anaer... 790 0.0
ref|YP_001353724.1| inosine-5'-monophosphate dehydrogenase ... 790 0.0
ref|YP_001099659.1| IMP dehydrogeanse [Herminiimonas arseni... 790 0.0
ref|ZP_02298794.1| inosine-5'-monophosphate dehydrogenase [... 789 0.0
ref|YP_391882.1| inosine-5'-monophosphate dehydrogenase [Th... 789 0.0
ref|YP_001239605.1| inositol-5-monophosphate dehydrogenase ... 789 0.0
ref|YP_001205198.1| inositol-5-monophosphate dehydrogenase ... 789 0.0
ref|NP_947545.1| inositol-5-monophosphate dehydrogenase [Rh... 789 0.0
ref|ZP_02992456.1| inosine-5'-monophosphate dehydrogenase [... 789 0.0
ref|YP_486800.1| inositol-5-monophosphate dehydrogenase [Rh... 789 0.0
dbj|BAG14171.1| IMP dehydrogenase [uncultured Termite group... 789 0.0
ref|XP_975747.1| PREDICTED: similar to Inosine-5-monophosph... 788 0.0
ref|XP_001245055.1| hypothetical protein CIMG_04496 [Coccid... 788 0.0
ref|ZP_02288166.1| inosine-5'-monophosphate dehydrogenase [... 787 0.0
ref|NP_370914.1| inositol-monophosphate dehydrogenase [Stap... 787 0.0
ref|YP_001767947.1| inosine-5'-monophosphate dehydrogenase ... 787 0.0
ref|YP_786091.1| inosine-5'-monophosphate dehydrogenase [Bo... 787 0.0
ref|ZP_03988119.1| inositol-monophosphate dehydrogenase [St... 787 0.0
ref|ZP_02185622.1| inositol-5-monophosphate dehydrogenase [... 787 0.0
ref|YP_912073.1| inosine-5'-monophosphate dehydrogenase [Ch... 787 0.0
ref|ZP_00986688.1| COG0516: IMP dehydrogenase/GMP reductase... 787 0.0
ref|NP_472228.1| guaB [Listeria innocua Clip11262] >gi|1680... 787 0.0
ref|ZP_02688926.1| inosine-5'-monophosphate dehydrogenase [... 787 0.0
ref|YP_318752.1| inositol-5-monophosphate dehydrogenase [Ni... 786 0.0
ref|YP_782181.1| inositol-5-monophosphate dehydrogenase [Rh... 786 0.0
ref|YP_001579470.1| inosine-5'-monophosphate dehydrogenase ... 786 0.0
Sequences not found previously or not previously below threshold:
ref|ZP_02616743.1| inosine-5'-monophosphate dehydrogenase [... 804 0.0
ref|NP_690931.1| inosine-5'-monophosphate dehydrogenase [Oc... 804 0.0
ref|YP_001393867.1| GuaB [Clostridium kluyveri DSM 555] >gi... 804 0.0
ref|ZP_01313162.1| inosine-5'-monophosphate dehydrogenase [... 802 0.0
ref|YP_356636.1| inosine-5'-monophosphate dehydrogenase [Pe... 800 0.0
ref|YP_302413.1| IMP dehydrogenase [Staphylococcus saprophy... 791 0.0
ref|YP_901677.1| inosine-5'-monophosphate dehydrogenase [Pe... 790 0.0
ref|YP_385243.1| IMP dehydrogenase [Geobacter metallireduce... 789 0.0
>ref|XP_001252299.1| PREDICTED: inosine monophosphate dehydrogenase 1 [Bos taurus]
Length = 660
Score = 886 bits (2291), Expect = 0.0, Method: Composition-based stats.
Identities = 269/500 (53%), Positives = 359/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 161 EDGLTAQQLFANADGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVT 220
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 221 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 280
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 281 IRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRNELVVAPAGVTL 340
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 341 KEANEILQRSKKGKLPIVNDRDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRE 400
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 401 DDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 460
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 461 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVV 520
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 521 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 580
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 581 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRT 640
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 641 MSAQIEGGVHGLHSYEKRLY 660
>ref|NP_000874.2| inosine monophosphate dehydrogenase 1 isoform a [Homo sapiens]
gb|EAL24310.1| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
Length = 599
Score = 879 bits (2273), Expect = 0.0, Method: Composition-based stats.
Identities = 269/500 (53%), Positives = 358/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 100 EDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 159
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 160 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 219
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 220 MRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTL 279
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 280 KEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRE 339
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 340 DDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 399
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 400 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVV 459
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 460 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 519
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 520 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRT 579
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 580 MSAQIEGGVHGLHSYEKRLY 599
>ref|NP_899066.1| inosine monophosphate dehydrogenase 1 isoform b [Homo sapiens]
gb|EAL24311.1| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
gb|AAH33622.2| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
Length = 563
Score = 879 bits (2272), Expect = 0.0, Method: Composition-based stats.
Identities = 269/500 (53%), Positives = 358/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 64 EDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 123
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 124 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 183
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 184 MRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTL 243
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 244 KEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRE 303
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 304 DDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 363
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 364 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVV 423
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 424 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 483
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 484 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRT 543
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 544 MSAQIEGGVHGLHSYEKRLY 563
>ref|NP_001096075.1| inosine monophosphate dehydrogenase 1 isoform c [Homo sapiens]
Length = 589
Score = 878 bits (2271), Expect = 0.0, Method: Composition-based stats.
Identities = 269/500 (53%), Positives = 358/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 90 EDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 149
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 150 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 209
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 210 MRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTL 269
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 270 KEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRE 329
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 330 DDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 389
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 390 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVV 449
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 450 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 509
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 510 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRT 569
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 570 MSAQIEGGVHGLHSYEKRLY 589
>ref|NP_001071309.1| inosine monophosphate dehydrogenase 1 [Bos taurus]
gb|AAI26585.1| IMP (inosine monophosphate) dehydrogenase 1 [Bos taurus]
Length = 571
Score = 878 bits (2270), Expect = 0.0, Method: Composition-based stats.
Identities = 269/500 (53%), Positives = 359/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 72 EDGLTAQQLFANADGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVT 131
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 132 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 191
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 192 IRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRNELVVAPAGVTL 251
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 252 KEANEILQRSKKGKLPIVNDRDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRE 311
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 312 DDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 371
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 372 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVV 431
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 432 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 491
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 492 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRT 551
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 552 MSAQIEGGVHGLHSYEKRLY 571
>gb|EDL13789.1| inosine 5'-phosphate dehydrogenase 1, isoform CRA_b [Mus musculus]
Length = 607
Score = 877 bits (2267), Expect = 0.0, Method: Composition-based stats.
Identities = 268/500 (53%), Positives = 359/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 108 EDGLTAQQLFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 167
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 168 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 227
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
+ G SGI +T G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 228 IQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRVELVVAPAGVTL 287
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 288 KEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRE 347
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 348 DDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 407
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 408 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVV 467
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 468 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 527
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 528 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRT 587
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 588 MSAQIEGGVHGLHSYEKRLY 607
>sp|P20839|IMDH1_HUMAN Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1)
(IMPDH-I) (IMPD 1)
Length = 514
Score = 876 bits (2265), Expect = 0.0, Method: Composition-based stats.
Identities = 269/500 (53%), Positives = 358/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 15 EDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 74
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 75 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 134
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 135 MRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTL 194
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 195 KEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRE 254
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 255 DDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 314
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 315 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVV 374
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 375 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 434
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 435 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRT 494
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 495 MSAQIEGGVHGLHSYEKRLY 514
>gb|EAW83652.1| IMP (inosine monophosphate) dehydrogenase 1, isoform CRA_d [Homo
sapiens]
Length = 522
Score = 876 bits (2265), Expect = 0.0, Method: Composition-based stats.
Identities = 269/500 (53%), Positives = 358/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 23 EDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 82
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 83 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 142
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 143 MRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTL 202
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 203 KEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRE 262
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 263 DDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 322
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 323 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVV 382
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 383 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 442
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 443 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRT 502
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 503 MSAQIEGGVHGLHSYEKRLY 522
>emb|CAK04261.1| novel protein similar to vertebrate IMP (inosine monophosphate)
dehydrogenase 1 (IMPDH1) [Danio rerio]
Length = 534
Score = 875 bits (2263), Expect = 0.0, Method: Composition-based stats.
Identities = 278/500 (55%), Positives = 362/500 (72%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF S +V+++ T+ I L PL+SSPMDTVT
Sbjct: 35 EDGLTAQQLFAIGDGLTYNDFLILPGFIDFISDEVDLTSALTRKITLKTPLISSPMDTVT 94
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
ESSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 95 ESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSPRHTVGDVFEAK 154
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI VTE GK KL+GIV ++DIDF KD P+ + MT+RE++ V + L
Sbjct: 155 VRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLSEKDYDRPLEESMTKREDLVVAPAGVTL 214
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA D+L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 215 KEANDILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGTRE 274
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L +AG+DV+VLDSSQGN+++Q+S I ++K+ YP L+VV GNVVT QAKNLI
Sbjct: 275 DDKYRLDLLMQAGVDVIVLDSSQGNSVFQISMINYIKQKYPELQVVGGNVVTAAQAKNLI 334
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG V
Sbjct: 335 DAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVV 394
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 395 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNNSSQKRYFSEG 454
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ ++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 455 DKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKFEKRT 514
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 515 MSAQVEGGVHGLHSYEKRLY 534
>pdb|1JCN|A Chain A, Binary Complex Of Human Type-I Inosine Monophosphate
Dehydrogenase With 6-Cl-Imp
pdb|1JCN|B Chain B, Binary Complex Of Human Type-I Inosine Monophosphate
Dehydrogenase With 6-Cl-Imp
Length = 514
Score = 871 bits (2253), Expect = 0.0, Method: Composition-based stats.
Identities = 268/500 (53%), Positives = 357/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ D L++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 15 EDGLTAQQLFASADDLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 74
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 75 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKNFEQGFITDPVVLSPSHTVGDVLEAK 134
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 135 MRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTL 194
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 195 KEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRE 254
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 255 DDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 314
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 315 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVV 374
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 375 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 434
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 435 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRT 494
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 495 MSAQIEGGVHGLHSYEKRLY 514
>ref|NP_001080792.1| inosine 5'-phosphate dehydrogenase 1 [Xenopus laevis]
gb|AAH46868.1| Impdh1-prov protein [Xenopus laevis]
Length = 514
Score = 870 bits (2250), Expect = 0.0, Method: Composition-based stats.
Identities = 273/500 (54%), Positives = 362/500 (72%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ +GL++NDF+ILPGFIDF + +V+++ T+ I L P++SSPMDTVT
Sbjct: 15 EDGLTAQQLFANSEGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPMISSPMDTVT 74
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
ES MA AMALMGGIG+IH+NCT E QA VR VK + GFI P +S + V + K
Sbjct: 75 ESDMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSLNHTVGDVFEAK 134
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
+ G SGI VTE GK KL+GIV ++DIDF KD S +S+ MT+RE++ V + L
Sbjct: 135 NRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLTEKDYSTYLSEVMTKREDLVVAPAGVTL 194
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 195 KEANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDCRKQLLCGAAIGTRE 254
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L +AG+DV+VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAKNLI
Sbjct: 255 DDKYRLDLLMQAGVDVVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKNLI 314
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D+LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP VADGG++ VG V
Sbjct: 315 DAGVDALRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVVADGGIQTVGHVV 374
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 375 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSTSSQKRYFSEG 434
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ ++VAQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ +RT
Sbjct: 435 DKVKVAQGVSGSIQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKLEKRT 494
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 495 MSAQVEGGVHGLHSYEKRLY 514
>gb|EAW83649.1| IMP (inosine monophosphate) dehydrogenase 1, isoform CRA_a [Homo
sapiens]
Length = 561
Score = 869 bits (2248), Expect = 0.0, Method: Composition-based stats.
Identities = 268/500 (53%), Positives = 357/500 (71%), Gaps = 5/500 (1%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 64 EDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 123
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR K + GFI P +SP V + K
Sbjct: 124 EADMAIAMALMGGIGFIHHNCTPEFQANEVR--KKFEQGFITDPVVLSPSHTVGDVLEAK 181
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 182 MRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTL 241
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 242 KEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRE 301
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 302 DDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 361
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 362 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVV 421
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 422 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 481
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 482 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRT 541
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 542 MSAQIEGGVHGLHSYEKRLY 561
>ref|NP_001017283.1| IMP (inosine monophosphate) dehydrogenase 1 [Xenopus tropicalis]
emb|CAJ83974.1| IMP (inosine monophosphate) dehydrogenase 1 [Xenopus tropicalis]
Length = 514
Score = 869 bits (2248), Expect = 0.0, Method: Composition-based stats.
Identities = 273/500 (54%), Positives = 361/500 (72%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA+ LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 15 EDGLTAQHLFANSDGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVT 74
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
ES MA AMALMGGIG+IH+NCT E QA VR VK + GFI P +S + V + K
Sbjct: 75 ESDMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSLNHTVGDVFEAK 134
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
+ G SGI VTE GK KL+GIV ++DIDF KD S +S+ MT+R+ + V + L
Sbjct: 135 NRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLTEKDYSTYLSEVMTKRDELVVAPAGVTL 194
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 195 KEANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDCRKQLLCGAAIGTRE 254
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG+DV+VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAKNLI
Sbjct: 255 DDKYRLDLLTQAGVDVVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKNLI 314
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D+LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 315 DAGVDALRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVV 374
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 375 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNTSSQKRYFSEG 434
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ ++VAQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ +RT
Sbjct: 435 DKVKVAQGVSGSIQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKLEKRT 494
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 495 MSAQVEGGVHGLHSYEKRLY 514
>ref|NP_035959.2| inosine 5'-phosphate dehydrogenase 1 [Mus musculus]
gb|AAH53416.1| Inosine 5'-phosphate dehydrogenase 1 [Mus musculus]
dbj|BAE42272.1| unnamed protein product [Mus musculus]
gb|EDL13790.1| inosine 5'-phosphate dehydrogenase 1, isoform CRA_c [Mus musculus]
Length = 514
Score = 869 bits (2248), Expect = 0.0, Method: Composition-based stats.
Identities = 268/500 (53%), Positives = 359/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 15 EDGLTAQQLFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 74
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 75 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 134
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
+ G SGI +T G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 135 IQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRVELVVAPAGVTL 194
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 195 KEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRE 254
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 255 DDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 314
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 315 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVV 374
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 375 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 434
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 435 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRT 494
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 495 MSAQIEGGVHGLHSYEKRLY 514
>gb|EDM15208.1| IMP (inosine monophosphate) dehydrogenase 1 (predicted), isoform
CRA_b [Rattus norvegicus]
Length = 514
Score = 869 bits (2247), Expect = 0.0, Method: Composition-based stats.
Identities = 268/500 (53%), Positives = 359/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 15 EDGLTAQQLFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 74
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 75 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 134
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
+ G SGI +T G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 135 IQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTL 194
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 195 KEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRE 254
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 255 DDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 314
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 315 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVV 374
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 375 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 434
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 435 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRT 494
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 495 MSAQIEGGVHGLHSYEKRLY 514
>ref|XP_001372080.1| PREDICTED: similar to Inosine monophosphate dehydrogenase 1
[Monodelphis domestica]
Length = 575
Score = 869 bits (2247), Expect = 0.0, Method: Composition-based stats.
Identities = 269/500 (53%), Positives = 357/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 76 EDGLTAQQLFAIADGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSPMDTVT 135
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 136 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 195
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R ++ V + L
Sbjct: 196 MRHGFSGIPITETGAMGSKLVGIVTSRDIDFLAEKDHATYLSEVMTGRNDLVVAPAGVTL 255
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 256 KEANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDAHKQLLCGAAVGTRE 315
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K YP L+V+ GNVVT QAKNLI
Sbjct: 316 DDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKHKYPQLQVIGGNVVTAAQAKNLI 375
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 376 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVV 435
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 436 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEG 495
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ ++VAQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 496 DKVKVAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRT 555
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 556 MSAQIEGGVHGLHSYEKRLY 575
>gb|EAW64946.1| hCG2002013, isoform CRA_a [Homo sapiens]
Length = 584
Score = 869 bits (2246), Expect = 0.0, Method: Composition-based stats.
Identities = 270/505 (53%), Positives = 363/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 80 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 139
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 140 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 199
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 200 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAP 259
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
I L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 260 AGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 319
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K YP+L+V+ GNVVT Q
Sbjct: 320 IGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQ 379
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 380 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 439
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 440 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 499
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 500 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 559
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 560 FEKRTSSAQVEGGVHSLHSYEKRLF 584
>ref|NP_001025772.1| inosine monophosphate dehydrogenase 2 [Gallus gallus]
emb|CAH65030.1| hypothetical protein [Gallus gallus]
Length = 514
Score = 868 bits (2245), Expect = 0.0, Method: Composition-based stats.
Identities = 271/499 (54%), Positives = 361/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LFS DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFSCGDGLTYNDFLILPGYIDFTADQVDLTSALTKRITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP+ V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPNDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKLE 189
G GI +T+ GK GKL+GI+ ++DIDF + P+ + MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDNGKMGGKLVGIISSRDIDFLKESEHDLPLGEIMTKREDLVVAPSGVMLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDSKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+D +VLDSSQGN+I+Q++ I+++K+ YP+L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLVQAGVDAVVLDSSQGNSIFQINMIKYIKEKYPNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNLGSQNRYFSETD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFIPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTT 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++LF
Sbjct: 496 SAQVEGGVHGLHSYEKRLF 514
>ref|XP_001494600.1| PREDICTED: similar to hCG2002013 [Equus caballus]
Length = 604
Score = 868 bits (2244), Expect = 0.0, Method: Composition-based stats.
Identities = 270/505 (53%), Positives = 362/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 100 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 159
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 160 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVKD 219
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 220 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAP 279
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
I L+EA ++L RS+ G LP++N DE+V + +R D + RDYP +S D LLC AA
Sbjct: 280 AGITLKEANEILQRSKKGKLPIVNKDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 339
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT Q
Sbjct: 340 IGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQ 399
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 400 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 459
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 460 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 519
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 520 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 579
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 580 FEKRTSSAQVEGGVHSLHSYEKRLF 604
>emb|CAI21140.1| novel protein similar to vertebrate IMP (inosine monophosphate)
dehydrogenase 1 (IMPDH1) [Danio rerio]
Length = 539
Score = 867 bits (2241), Expect = 0.0, Method: Composition-based stats.
Identities = 277/502 (55%), Positives = 368/502 (73%), Gaps = 3/502 (0%)
Query: 10 TLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDT 68
++RDG TAEELFS+ DG+++NDF+ILPGFIDF S +V+++ TK I L PL+SSPMDT
Sbjct: 38 SVRDGHTAEELFSKGDGMTYNDFLILPGFIDFTSDEVDLTSALTKKITLKTPLISSPMDT 97
Query: 69 VTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRN 128
VTESSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V +
Sbjct: 98 VTESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKRFEQGFITDPVVLSPHHTVGDVLE 157
Query: 129 IKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPI 186
K G SGI +TE GK KL+GIV ++DIDF KD + + + MT+RE++ V +
Sbjct: 158 AKVRHGFSGIPITETGKMGSKLVGIVTSRDIDFLSEKDNNKYLEEAMTKREDLVVAPAGV 217
Query: 187 KLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATST 246
L+EA D+L RS+ G LP++NDKDE+V + +R D + RDYP +S D LLC AA T
Sbjct: 218 TLKEANDILQRSKKGKLPIVNDKDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGT 277
Query: 247 READKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKN 306
RE DK R+ L+++G+D++VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAKN
Sbjct: 278 REDDKYRLDLLTQSGVDMVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKN 337
Query: 307 LIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGD 366
LIDAG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG
Sbjct: 338 LIDAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGH 397
Query: 367 VCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLS 426
V KAL++GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY S
Sbjct: 398 VVKALSLGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNTSSQKRYFS 457
Query: 427 ENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNR 486
E + ++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +
Sbjct: 458 EGDKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSVLRSMMYSGELKFEK 517
Query: 487 RTLTAQSEGAVHSLHHYERKLF 508
RT++AQ EG VH LH +E++L+
Sbjct: 518 RTMSAQVEGGVHGLHSFEKRLY 539
>ref|XP_001110855.1| PREDICTED: inosine monophosphate dehydrogenase 2 isoform 6 [Macaca
mulatta]
Length = 514
Score = 866 bits (2238), Expect = 0.0, Method: Composition-based stats.
Identities = 270/505 (53%), Positives = 364/505 (72%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCLLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
I L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP+L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>ref|NP_001002177.1| hypothetical protein LOC431724 [Danio rerio]
gb|AAH74090.1| Zgc:91911 [Danio rerio]
emb|CAN87720.1| novel protein (zgc:91911) [Danio rerio]
gb|AAI65226.1| Zgc:91911 protein [synthetic construct]
Length = 544
Score = 866 bits (2238), Expect = 0.0, Method: Composition-based stats.
Identities = 276/495 (55%), Positives = 357/495 (72%), Gaps = 3/495 (0%)
Query: 12 RDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ DGL++NDF+ILPGFIDF S +V+++ T+ I L PL+SSPMDTVT
Sbjct: 15 EDGLTAQQLFAIGDGLTYNDFLILPGFIDFISDEVDLTSALTRKITLKTPLISSPMDTVT 74
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
ESSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 75 ESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSPRHTVGDVFEAK 134
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI VTE GK KL+GIV ++DIDF KD P+ + MT+RE++ V + L
Sbjct: 135 VRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLSEKDYDRPLEESMTKREDLVVAPAGVTL 194
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA D+L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 195 KEANDILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGTRE 254
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L +AG+DV+VLDSSQGN+++Q+S I ++K+ YP L+VV GNVVT QAKNLI
Sbjct: 255 DDKYRLDLLMQAGVDVIVLDSSQGNSVFQISMINYIKQKYPELQVVGGNVVTAAQAKNLI 314
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG V
Sbjct: 315 DAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVV 374
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE
Sbjct: 375 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNNSSQKRYFSEG 434
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ ++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 435 DKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELKFEKRT 494
Query: 489 LTAQSEGAVHSLHHY 503
++AQ EG VH LH Y
Sbjct: 495 MSAQVEGGVHGLHSY 509
>ref|NP_001014391.1| hypothetical protein LOC338306 [Danio rerio]
emb|CAI21139.1| novel protein similar to vertebrate IMP (inosine monophosphate)
dehydrogenase 1 (IMPDH1) [Danio rerio]
gb|AAH91790.1| Si:dkey-31f5.7 [Danio rerio]
Length = 514
Score = 865 bits (2236), Expect = 0.0, Method: Composition-based stats.
Identities = 273/499 (54%), Positives = 364/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG +A++LF+ DGL++NDF+ILPGFIDF S +V+++ TK I L PL+SSPMDTVTE
Sbjct: 16 DGLSAQQLFAVGDGLTYNDFLILPGFIDFTSDEVDLTSALTKKITLKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
SSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 76 SSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKRFEQGFITDPVVLSPHHTVGDVLEAKV 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKLE 189
G SGI +TE GK KL+GIV ++DIDF KD + + + MT+RE++ V + L+
Sbjct: 136 RHGFSGIPITETGKMGSKLVGIVTSRDIDFLSEKDNNKYLEEAMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA D+L RS+ G LP++NDKDE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 196 EANDILQRSKKGKLPIVNDKDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAAIGTRED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L+++G+D++VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT QAKNLID
Sbjct: 256 DKYRLDLLTQSGVDMVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++ VG V K
Sbjct: 316 AGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQTVGHVVK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
AL++GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALSLGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNTSSQKRYFSEGD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT+
Sbjct: 436 KVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSVLRSMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH +E++L+
Sbjct: 496 SAQVEGGVHGLHSFEKRLY 514
>ref|XP_850933.1| PREDICTED: similar to inosine 5-phosphate dehydrogenase 2 isoform 2
[Canis familiaris]
Length = 514
Score = 864 bits (2235), Expect = 0.0, Method: Composition-based stats.
Identities = 270/505 (53%), Positives = 363/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
I L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPTLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>ref|NP_000875.2| inosine monophosphate dehydrogenase 2 [Homo sapiens]
sp|P12268|IMDH2_HUMAN Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2)
(IMPDH-II) (IMPD 2)
pdb|1B3O|A Chain A, Ternary Complex Of Human Type-Ii Inosine Monophosphate
Dehydrogenase With 6-Cl-Imp And Selenazole Adenine
Dinucleotide
pdb|1B3O|B Chain B, Ternary Complex Of Human Type-Ii Inosine Monophosphate
Dehydrogenase With 6-Cl-Imp And Selenazole Adenine
Dinucleotide
pdb|1NF7|A Chain A, Ternary Complex Of The Human Type Ii Inosine Monophosphate
Dedhydrogenase With Ribavirin Monophosphate And C2-
Mycophenolic Adenine Dinucleotide
pdb|1NF7|B Chain B, Ternary Complex Of The Human Type Ii Inosine Monophosphate
Dedhydrogenase With Ribavirin Monophosphate And C2-
Mycophenolic Adenine Dinucleotide
pdb|1NFB|A Chain A, Ternary Complex Of The Human Type Ii Inosine Monophosphate
Dedhydrogenase With 6cl-Imp And Nad
pdb|1NFB|B Chain B, Ternary Complex Of The Human Type Ii Inosine Monophosphate
Dedhydrogenase With 6cl-Imp And Nad
gb|AAA67054.1| inosine monophosphate dehydrogenase type II
gb|AAB70699.1| inosine monophosphate dehydrogenase type II [Homo sapiens]
gb|AAH06124.1| IMP (inosine monophosphate) dehydrogenase 2 [Homo sapiens]
gb|AAH12840.1| IMP (inosine monophosphate) dehydrogenase 2 [Homo sapiens]
gb|AAH15567.1| IMP (inosine monophosphate) dehydrogenase 2 [Homo sapiens]
gb|ABM84329.1| IMP (inosine monophosphate) dehydrogenase 2 [synthetic construct]
gb|ABM87720.1| IMP (inosine monophosphate) dehydrogenase 2 [synthetic construct]
Length = 514
Score = 864 bits (2233), Expect = 0.0, Method: Composition-based stats.
Identities = 270/505 (53%), Positives = 363/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
I L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K YP+L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>ref|XP_001367707.1| PREDICTED: similar to hCG2002013, [Monodelphis domestica]
Length = 514
Score = 863 bits (2231), Expect = 0.0, Method: Composition-based stats.
Identities = 269/499 (53%), Positives = 361/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSPMDTVTE
Sbjct: 16 DGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 AGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKLE 189
G GI +T+ GK +L+GI+ ++DIDF ++ + + MTRRE++ V + L+
Sbjct: 136 RHGFCGIPITDNGKMGSRLVGIISSRDIDFLKEEEHDRFLDEIMTRREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA T E
Sbjct: 196 EANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDTKKQLLCGAAIGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ Y +L+V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYNNLQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + K
Sbjct: 316 AGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNLGSQNRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTS 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++LF
Sbjct: 496 SAQVEGGVHGLHSYEKRLF 514
>ref|NP_035960.2| inosine 5'-phosphate dehydrogenase 2 [Mus musculus]
sp|P24547|IMDH2_MOUSE Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2)
(IMPDH-II) (IMPD 2)
gb|AAH10314.1| Inosine 5'-phosphate dehydrogenase 2 [Mus musculus]
gb|AAH52671.1| Inosine 5'-phosphate dehydrogenase 2 [Mus musculus]
dbj|BAE35879.1| unnamed protein product [Mus musculus]
dbj|BAE40908.1| unnamed protein product [Mus musculus]
dbj|BAE41367.1| unnamed protein product [Mus musculus]
dbj|BAE38929.1| unnamed protein product [Mus musculus]
dbj|BAE29791.1| unnamed protein product [Mus musculus]
dbj|BAE30225.1| unnamed protein product [Mus musculus]
dbj|BAE35402.1| unnamed protein product [Mus musculus]
dbj|BAE31422.1| unnamed protein product [Mus musculus]
gb|EDL21302.1| inosine 5'-phosphate dehydrogenase 2 [Mus musculus]
Length = 514
Score = 863 bits (2231), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 362/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>sp|P12269|IMDH2_CRIGR Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2)
(IMPDH-II) (IMPD 2)
pir||B31997 IMP dehydrogenase (EC 1.1.1.205) - Chinese hamster
pdb|1JR1|A Chain A, Crystal Structure Of Inosine Monophosphate Dehydrogenase
In Complex With Mycophenolic Acid
pdb|1JR1|B Chain B, Crystal Structure Of Inosine Monophosphate Dehydrogenase
In Complex With Mycophenolic Acid
gb|AAA36993.1| inosine-5'-monophosphate dehydrogenase
Length = 514
Score = 863 bits (2230), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 362/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
I L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGITLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP+L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYMKEKYPNLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMG GSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGCGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>ref|NP_001029588.1| IMP (inosine monophosphate) dehydrogenase 2 [Bos taurus]
sp|Q3SWY3|IMDH2_BOVIN Inosine-5'-monophosphate dehydrogenase 2 (IMP dehydrogenase 2)
(IMPDH-II) (IMPD 2)
gb|AAI04603.1| IMP (inosine monophosphate) dehydrogenase 2 [Bos taurus]
Length = 514
Score = 863 bits (2230), Expect = 0.0, Method: Composition-based stats.
Identities = 270/505 (53%), Positives = 362/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPRDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSHLVGIISSRDIDFLKEEEHDRLLGEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
I L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGITLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ LS+AG+DV+VLDSSQGN+I+Q++ I+++K+ YP ++V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLSQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSIQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>sp|P50096|IMDH1_MOUSE Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1)
(IMPDH-I) (IMPD 1)
gb|AAA18285.1| type I inosine monophosphate dehydrogenase
Length = 514
Score = 863 bits (2230), Expect = 0.0, Method: Composition-based stats.
Identities = 267/500 (53%), Positives = 357/500 (71%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA ELF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 15 EDGLTAHELFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 74
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 75 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAK 134
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
+ G SGI +T G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 135 IQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRVELVVAPAGVTL 194
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA TRE
Sbjct: 195 KEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTRE 254
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG DV+V DSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 255 DDKYRLDLLTQAGADVIVHDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 314
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 315 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQTVGHVV 374
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRG+GS+DAM + S KRY SE
Sbjct: 375 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGIGSLDAMEKSSSSQKRYFSEG 434
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 435 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELKFEKRT 494
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++AQ EG VH LH YE++L+
Sbjct: 495 MSAQIEGGVHGLHSYEKRLY 514
>gb|AAA36114.1| IMP dehydrogenase type 1 (EC 1.1.1.205)
Length = 514
Score = 862 bits (2228), Expect = 0.0, Method: Composition-based stats.
Identities = 264/500 (52%), Positives = 353/500 (70%), Gaps = 3/500 (0%)
Query: 12 RDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVT 70
DG TA++LF+ D L++NDF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVT
Sbjct: 15 EDGLTAQQLFASADDLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVT 74
Query: 71 ESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIK 130
E+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V + K
Sbjct: 75 EADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKNFEQGFITDPVVLSPSHTVGDVLEAK 134
Query: 131 SEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKL 188
G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V + L
Sbjct: 135 MRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTL 194
Query: 189 EEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTRE 248
+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA TRE
Sbjct: 195 KEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTRE 254
Query: 249 ADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLI 308
DK R+ L++AG+DV+V SSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLI
Sbjct: 255 DDKYRLDLLTQAGVDVIVFHSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLI 314
Query: 309 DAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVC 368
DAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V
Sbjct: 315 DAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVV 374
Query: 369 KALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSEN 428
KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+D M + S KRY SE
Sbjct: 375 KALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDPMEKSSSSQKRYFSEG 434
Query: 429 ETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRT 488
+ +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++ F +RT
Sbjct: 435 DKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRT 494
Query: 489 LTAQSEGAVHSLHHYERKLF 508
++ Q EG VH LH YE++L+
Sbjct: 495 MSPQIEGGVHGLHSYEKRLY 514
>gb|AAA39311.1| IMP dehydrogenase (EC 1.2.1.14)
Length = 514
Score = 861 bits (2227), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 361/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMTYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>ref|XP_001478203.1| PREDICTED: similar to Inosine 5-phosphate dehydrogenase 2 [Mus
musculus]
Length = 514
Score = 861 bits (2227), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 361/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALAFGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>gb|AAA36112.1| inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)
Length = 514
Score = 861 bits (2227), Expect = 0.0, Method: Composition-based stats.
Identities = 270/505 (53%), Positives = 363/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
I L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 RSITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K YP+L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>dbj|BAE30628.1| unnamed protein product [Mus musculus]
Length = 514
Score = 861 bits (2226), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 361/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L+ AG+DV+VLDSSQGN+I Q++ I+++K+ YP L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLALAGVDVVVLDSSQGNSISQINMIKYIKEKYPSLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>ref|NP_001082410.1| similar to inosine 5'-phosphate dehydrogenase 2 [Xenopus laevis]
gb|AAH42315.1| MGC53627 protein [Xenopus laevis]
Length = 514
Score = 860 bits (2224), Expect = 0.0, Method: Composition-based stats.
Identities = 277/499 (55%), Positives = 365/499 (73%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG TA++LF + DGL++NDF+ILPG+IDF + +V+++ TK I L P+VSSPMDTVTE
Sbjct: 16 DGLTAQQLFGAGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPMVSSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
++MA AMAL GGIGVIH+NCT E QA VR VK Y GFI P +SP V + K+
Sbjct: 76 ANMAIAMALTGGIGVIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKHCVRHVFEAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDFVK--DASAPVSQYMTRRENMTVERYPIKLE 189
G GI +TE GK KL GI+ ++DIDF+K D +S+ MTRRE++ V + L+
Sbjct: 136 RHGFCGIPITENGKMGSKLAGIISSRDIDFLKAEDHDLALSEIMTRREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N DE+V + +R D + RDYP +S D LLC AAT T E
Sbjct: 196 EANEILQRSKKGKLPIVNGDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAATGTHED 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L +AG+D +VLDSSQGN+I+Q++ I+++K+ YP L+V+AGNVVT QAKNLID
Sbjct: 256 DKYRLDLLVQAGVDAVVLDSSQGNSIFQINMIKYIKEKYPDLQVIAGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AGAD+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE +
Sbjct: 376 ALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNVSSQKRYFSEAD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT+
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFIPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VH LH YE++LF
Sbjct: 496 SAQVEGGVHGLHSYEKRLF 514
>dbj|BAE25403.1| unnamed protein product [Mus musculus]
Length = 514
Score = 860 bits (2224), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 362/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNEYDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>emb|CAQ13978.1| IMP (inosine monophosphate) dehydrogenase 2 [Danio rerio]
Length = 514
Score = 860 bits (2224), Expect = 0.0, Method: Composition-based stats.
Identities = 267/499 (53%), Positives = 365/499 (73%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG T ++LF S DGL++NDF+ILPG+IDF + +V+++ TK I + PL+SSPMDTVTE
Sbjct: 16 DGLTGQQLFNSGDGLTYNDFLILPGYIDFTADQVDLTSALTKQITMKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
S MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP+ V + K+
Sbjct: 76 SGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKRYEQGFITDPVVMSPNERVRDVFQAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ G+L+GI+ ++DIDF + P+S+ MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDNGQMGGRLVGIISSRDIDFLKESEHDLPLSEVMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N++ +V + +R D + RD+P +S D LLC AA T
Sbjct: 196 EANEILQRSKKGKLPIVNEEGCLVAIIARTDLKKNRDFPLASKDSRKQLLCGAAIGTHND 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP+++V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNVQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AGAD+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A TSE PGEYFF DG+RLK YRGMGS+DAM + S RY SE++
Sbjct: 376 ALALGASTVMMGSLLAATSEAPGEYFFSDGIRLKKYRGMGSLDAMDKNLGSQTRYFSESD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT+
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLLVGIQHSCQDIGAKSLTQLRAMMYSGELRFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHSLH YE++LF
Sbjct: 496 SAQMEGGVHSLHSYEKRLF 514
>ref|XP_516452.2| PREDICTED: inosine monophosphate dehydrogenase 2 [Pan troglodytes]
Length = 608
Score = 860 bits (2223), Expect = 0.0, Method: Composition-based stats.
Identities = 269/529 (50%), Positives = 362/529 (68%), Gaps = 27/529 (5%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 80 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 139
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 140 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 199
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 200 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAP 259
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
I L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 260 AGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 319
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K YP+L+V+ GNVVT Q
Sbjct: 320 IGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQ 379
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVL------------------------ACGRPQAT 339
AKNLIDAG D+LR+GMGSGSICITQEV ACGRPQAT
Sbjct: 380 AKNLIDAGVDALRVGMGSGSICITQEVAPKIPPDIKSHSPKCPSTVTGCYMLACGRPQAT 439
Query: 340 AIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDG 399
A+YKV+ YA GVP +ADGG++NVG + KALA+GA+ M+GS++A T+E PGEYFF DG
Sbjct: 440 AVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDG 499
Query: 400 MRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQ 459
+RLK YRGMGS+DAM + S RY SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q
Sbjct: 500 IRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQ 559
Query: 460 QSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAVHSLHHYERKLF 508
S QDIG S +R +Y G++ F +RT +AQ EG VHSLH YE++LF
Sbjct: 560 HSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 608
>ref|XP_862835.1| PREDICTED: similar to Inosine-5-monophosphate dehydrogenase 2 (IMP
dehydrogenase 2) (IMPDH-II) (IMPD 2) isoform 7 [Canis
familiaris]
Length = 520
Score = 859 bits (2221), Expect = 0.0, Method: Composition-based stats.
Identities = 270/511 (52%), Positives = 363/511 (71%), Gaps = 9/511 (1%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKV------NVSGQFTKNILLHL 59
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V +++ TK I L
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVLAVFPQDLTSALTKKITLKT 69
Query: 60 PLVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSP 119
PLVSSPMDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP
Sbjct: 70 PLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSP 129
Query: 120 DVPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRE 177
V + K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE
Sbjct: 130 KDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKRE 189
Query: 178 NMTVERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGH 237
++ V I L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D
Sbjct: 190 DLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQ 249
Query: 238 LLCAAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGN 297
LLC AA T E DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GN
Sbjct: 250 LLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPTLQVIGGN 309
Query: 298 VVTQDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVA 357
VVT QAKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +A
Sbjct: 310 VVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIA 369
Query: 358 DGGLRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQG 417
DGG++NVG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM +
Sbjct: 370 DGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKH 429
Query: 418 RESGKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKV 477
S RY SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +
Sbjct: 430 LSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMM 489
Query: 478 YEGQVLFNRRTLTAQSEGAVHSLHHYERKLF 508
Y G++ F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 YSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 520
>gb|AAA20181.1| IMP dehydrogenase
Length = 514
Score = 859 bits (2220), Expect = 0.0, Method: Composition-based stats.
Identities = 268/505 (53%), Positives = 360/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICI QEVLACGRPQATA+YKV YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICIIQEVLACGRPQATAVYKVYEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHSLHSYEKRLF 514
>ref|NP_954530.1| inosine monophosphate dehydrogenase 2 [Rattus norvegicus]
gb|AAH60585.1| Inosine 5-monophosphate dehydrogenase 2 [Rattus norvegicus]
Length = 514
Score = 858 bits (2219), Expect = 0.0, Method: Composition-based stats.
Identities = 267/505 (52%), Positives = 361/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNESDELVAIIARTDLKKNRDYPLASKDTKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L+ AG+DV+VLDSSQGN+I+Q++ I+++K+ YP+L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMGSGSICITQEVLA GRPQATA+YKV+ YA GVP +ADGG++N
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVLASGRPQATAVYKVSEYARRFGVPVIADGGIQN 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S R
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT +AQ EG VH LH YE++LF
Sbjct: 490 FEKRTSSAQVEGGVHGLHSYEKRLF 514
>ref|NP_958872.1| inosine monophosphate dehydrogenase 2 [Danio rerio]
gb|AAH46905.1| IMP (inosine monophosphate) dehydrogenase 2 [Danio rerio]
Length = 514
Score = 858 bits (2217), Expect = 0.0, Method: Composition-based stats.
Identities = 266/499 (53%), Positives = 364/499 (72%), Gaps = 3/499 (0%)
Query: 13 DGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTE 71
DG T ++LF S DGL++NDF+ILPG+IDF + +V+++ TK I + PL+SSPMDTVTE
Sbjct: 16 DGLTGQQLFNSGDGLTYNDFLILPGYIDFTADQVDLTSALTKQITMKTPLISSPMDTVTE 75
Query: 72 SSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKS 131
S MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP+ V + K+
Sbjct: 76 SGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKRYEQGFITDPVVMSPNERVRDVFQAKA 135
Query: 132 EKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKLE 189
G GI +T+ G+ G+L+GI+ ++DIDF + P+S+ MT+RE++ V + L+
Sbjct: 136 RHGFCGIPITDNGQMGGRLVGIISSRDIDFLKESEHDLPLSEVMTKREDLVVAPAGVTLK 195
Query: 190 EAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREA 249
EA ++L RS+ G LP++N++ +V + +R D + RD+P +S D LLC AA T
Sbjct: 196 EANEILQRSKKGKLPIVNEEGCLVAIIARTDLKKNRDFPLASKDSRKQLLCGAAIGTHND 255
Query: 250 DKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLID 309
DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP+++V+ GNVVT QAKNLID
Sbjct: 256 DKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPNVQVIGGNVVTAAQAKNLID 315
Query: 310 AGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCK 369
AGAD+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++ VG + K
Sbjct: 316 AGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAK 375
Query: 370 ALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE 429
ALA+GA+ M+GS++A TSE PGEYFF DG+RLK YRGMGS+DAM + S RY SE++
Sbjct: 376 ALALGASTVMMGSLLAATSEAPGEYFFSDGIRLKKYRGMGSLDAMDKNLGSQTRYFSESD 435
Query: 430 TLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTL 489
++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT+
Sbjct: 436 KIKVAQGVSGAVQDKGSIHKFVPYLLVGIQHSCQDIGAKSLTQLRAMMYSGELRFEKRTM 495
Query: 490 TAQSEGAVHSLHHYERKLF 508
+AQ EG VHS H YE++LF
Sbjct: 496 SAQMEGGVHSQHSYEKRLF 514
>ref|XP_862898.1| PREDICTED: similar to Inosine-5-monophosphate dehydrogenase 2 (IMP
dehydrogenase 2) (IMPDH-II) (IMPD 2) isoform 9 [Canis
familiaris]
Length = 538
Score = 856 bits (2214), Expect = 0.0, Method: Composition-based stats.
Identities = 269/529 (50%), Positives = 362/529 (68%), Gaps = 27/529 (5%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V+++ TK I L PLVSSP
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + + MT+RE++ V
Sbjct: 130 VFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
I L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L+V+ GNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPTLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVL------------------------ACGRPQAT 339
AKNLIDAG D+LR+GMGSGSICITQEV ACGRPQAT
Sbjct: 310 AKNLIDAGVDALRVGMGSGSICITQEVAPKIPPDIKSHSPKCPSTVKGCYMLACGRPQAT 369
Query: 340 AIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDG 399
A+YKV+ YA GVP +ADGG++NVG + KALA+GA+ M+GS++A T+E PGEYFF DG
Sbjct: 370 AVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDG 429
Query: 400 MRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQ 459
+RLK YRGMGS+DAM + S RY SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q
Sbjct: 430 IRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQ 489
Query: 460 QSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAVHSLHHYERKLF 508
S QDIG S +R +Y G++ F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 HSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 538
>ref|XP_533835.2| PREDICTED: similar to inosine 5-phosphate dehydrogenase 2 isoform 1
[Canis familiaris]
Length = 526
Score = 856 bits (2214), Expect = 0.0, Method: Composition-based stats.
Identities = 270/517 (52%), Positives = 363/517 (70%), Gaps = 15/517 (2%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKV------------NVSGQFTK 53
+ DG TA++LF+ DGL++NDF+ILPG+IDF + +V +++ TK
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVVSMARNWVLSVKDLTSALTK 69
Query: 54 NILLHLPLVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMK 113
I L PLVSSPMDTVTE+ MA AMAL GGIG IH+NCT E QA VR VK Y GFI
Sbjct: 70 KITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITD 129
Query: 114 PKSVSPDVPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQ 171
P +SP V + K+ G GI +T+ G+ +L+GI+ ++DIDF ++ + +
Sbjct: 130 PVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEE 189
Query: 172 YMTRRENMTVERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSS 231
MT+RE++ V I L+EA ++L RS+ G LP++N+ DE+V + +R D + RDYP +S
Sbjct: 190 IMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLAS 249
Query: 232 LDRNGHLLCAAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHL 291
D LLC AA T E DK R+ L++AG+DV+VLDSSQGN+I+Q++ I+++K+ YP L
Sbjct: 250 KDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKEKYPTL 309
Query: 292 EVVAGNVVTQDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASR 351
+V+ GNVVT QAKNLIDAG D+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA
Sbjct: 310 QVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRF 369
Query: 352 GVPCVADGGLRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSI 411
GVP +ADGG++NVG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+
Sbjct: 370 GVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSL 429
Query: 412 DAMLQGRESGKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFD 471
DAM + S RY SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S
Sbjct: 430 DAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLT 489
Query: 472 AIREKVYEGQVLFNRRTLTAQSEGAVHSLHHYERKLF 508
+R +Y G++ F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 QVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 526
>ref|XP_862874.1| PREDICTED: similar to Inosine-5-monophosphate dehydrogenase 2 (IMP
dehydrogenase 2) (IMPDH-II) (IMPD 2) isoform 8 [Canis
familiaris]
Length = 541
Score = 856 bits (2213), Expect = 0.0, Method: Composition-based stats.
Identities = 269/532 (50%), Positives = 363/532 (68%), Gaps = 30/532 (5%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSF---------------------------NDFIILPGFI 38
+ DG TA++LF+ DGL++ +DF+ILPG+I
Sbjct: 10 TSYVPDDGLTAQQLFNCGDGLTYKCGPSGLTWARSCPNPEPYSQFTPLPRSDFLILPGYI 69
Query: 39 DFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARAMALMGGIGVIHNNCTVEQQAR 98
DF + +V+++ TK I L PLVSSPMDTVTE+ MA AMAL GGIG IH+NCT E QA
Sbjct: 70 DFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQAN 129
Query: 99 MVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISGILVTEGGKYDGKLLGIVCTKD 158
VR VK Y GFI P +SP V + K+ G GI +T+ G+ +L+GI+ ++D
Sbjct: 130 EVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRD 189
Query: 159 IDF--VKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLC 216
IDF ++ + + MT+RE++ V I L+EA ++L RS+ G LP++N+ DE+V +
Sbjct: 190 IDFLKEEEHDRFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAII 249
Query: 217 SRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAALSEAGIDVLVLDSSQGNTIY 276
+R D + RDYP +S D LLC AA T E DK R+ L++AG+DV+VLDSSQGN+I+
Sbjct: 250 ARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIF 309
Query: 277 QVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRIGMGSGSICITQEVLACGRP 336
Q++ I+++K+ YP L+V+ GNVVT QAKNLIDAG D+LR+GMGSGSICITQEVLACGRP
Sbjct: 310 QINMIKYIKEKYPTLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRP 369
Query: 337 QATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANVAMLGSMIAGTSETPGEYFF 396
QATA+YKV+ YA GVP +ADGG++NVG + KALA+GA+ M+GS++A T+E PGEYFF
Sbjct: 370 QATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFF 429
Query: 397 KDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGVAGAVLDKGSVLKLLAYIHK 456
DG+RLK YRGMGS+DAM + S RY SE + ++VAQGV+GAV DKGS+ K + Y+
Sbjct: 430 SDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIA 489
Query: 457 GLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAVHSLHHYERKLF 508
G+Q S QDIG S +R +Y G++ F +RT +AQ EG VHSLH YE++LF
Sbjct: 490 GIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF 541
>ref|NP_001008066.1| IMP (inosine monophosphate) dehydrogenase 2 [Xenopus tropicalis]
gb|AAH80955.1| IMP (inosine monophosphate) dehydrogenase 2 [Xenopus tropicalis]
emb|CAJ83737.1| IMP (inosine monophosphate) dehydrogenase 2 [Xenopus tropicalis]
Length = 514
Score = 854 bits (2207), Expect = 0.0, Method: Composition-based stats.
Identities = 273/505 (54%), Positives = 364/505 (72%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELF-SQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
+ DG TA++LF + DGL++NDF+ILPG+IDF + +V+++ TK I L P+VSSP
Sbjct: 10 TSYVPDDGLTAQQLFGAGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPMVSSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+SMA AMAL GGIG++H+NCT E QA VR VK Y GFI P +SP V
Sbjct: 70 MDTVTEASMAIAMALTGGIGIMHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKHRVRD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDFVK--DASAPVSQYMTRRENMTVER 183
+ K+ G GI +TE GK KL GI+ ++DIDF+K + +S+ MTRRE++ V
Sbjct: 130 VFEAKARHGFCGIPITENGKMGSKLAGIISSRDIDFLKSEEHDLALSEIMTRREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++N DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNGNDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
T E DK R+ L +AG+D +VLDSSQGN+I+Q++ I+++K+ Y L+V+AGNVVT Q
Sbjct: 250 IGTHEDDKYRLDLLVQAGVDAVVLDSSQGNSIFQINMIKFIKEKYQDLQVIAGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAGAD+LR+GMGSGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++
Sbjct: 310 AKNLIDAGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQT 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG + KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 370 VGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNVSSQKR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+GAV DKGS+ K + Y+ G+Q S QDIG S +R +Y G++
Sbjct: 430 YFSEADKIKVAQGVSGAVQDKGSIHKFIPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++LF
Sbjct: 490 FEKRTMSAQVEGGVHGLHSYEKRLF 514
>ref|XP_001505397.1| PREDICTED: similar to hCG2002013 [Ornithorhynchus anatinus]
Length = 665
Score = 854 bits (2207), Expect = 0.0, Method: Composition-based stats.
Identities = 256/488 (52%), Positives = 350/488 (71%), Gaps = 2/488 (0%)
Query: 23 QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARAMALMG 82
+ G++ +DF+ILPG+IDF + +V+++ TK I L PL+SSPMDTVTE+ MA AMAL G
Sbjct: 178 RGGITHSDFLILPGYIDFTADQVDLTSALTKKITLKTPLISSPMDTVTEAGMAIAMALTG 237
Query: 83 GIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISGILVTE 142
GIG IH+NCT E QA VR VK Y GFI P +SP V + K+ G GI +T+
Sbjct: 238 GIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITD 297
Query: 143 GGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNRSRH 200
GK +L+GI+ ++DIDF ++ + + MT+ E++ V + L+EA ++L RS+
Sbjct: 298 NGKMGSRLMGIISSRDIDFLKEEEHDLYLGEIMTKWEDLVVAPAGVTLKEANEILQRSKK 357
Query: 201 GYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAALSEA 260
G LP++N+ +E+V + +R D + RDYP +S D LLC AA T E DK R+ L++A
Sbjct: 358 GKLPIVNEDNELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQA 417
Query: 261 GIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRIGMG 320
G+DV+VLDSSQGN+I+Q++ I+++K+ Y +L+V+ GNVVT QAKNLIDAG D+LR+GMG
Sbjct: 418 GVDVVVLDSSQGNSIFQINMIKYIKEKYHNLQVIGGNVVTAAQAKNLIDAGVDALRVGMG 477
Query: 321 SGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANVAML 380
SGSICITQEVLACGRPQATA+YKV+ YA GVP +ADGG++NVG + KALA+GA+ M+
Sbjct: 478 SGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMM 537
Query: 381 GSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGVAGA 440
GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S RY SE + ++VAQGV+GA
Sbjct: 538 GSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNLGSQNRYFSEADKIKVAQGVSGA 597
Query: 441 VLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAVHSL 500
V DKGS+ K + Y+ G+Q S QDIG S +R +Y G++ F +RT +AQ EG VH L
Sbjct: 598 VQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTLVRAMMYSGELKFEKRTSSAQVEGGVHGL 657
Query: 501 HHYERKLF 508
H YE++LF
Sbjct: 658 HSYEKRLF 665
>ref|XP_001089341.1| PREDICTED: similar to inosine monophosphate dehydrogenase 1 isoform
b [Macaca mulatta]
Length = 530
Score = 852 bits (2204), Expect = 0.0, Method: Composition-based stats.
Identities = 259/481 (53%), Positives = 345/481 (71%), Gaps = 2/481 (0%)
Query: 30 DFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARAMALMGGIGVIHN 89
DF+ILPGFIDF + +V+++ T+ I L PL+SSPMDTVTE+ MA AMALMGGIG IH+
Sbjct: 50 DFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHH 109
Query: 90 NCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISGILVTEGGKYDGK 149
NCT E QA VR VK + GFI P +SP V + K G SGI +TE G K
Sbjct: 110 NCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSK 169
Query: 150 LLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNRSRHGYLPVLN 207
L+GIV ++DIDF KD + +S+ MT R + V + L+EA ++L RS+ G LP++N
Sbjct: 170 LVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVN 229
Query: 208 DKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAALSEAGIDVLVL 267
D+DE+V + +R D + RDYP +S D + LLC AA TRE DK R+ L++AG+DV+VL
Sbjct: 230 DRDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVL 289
Query: 268 DSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRIGMGSGSICIT 327
DSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT QAKNLIDAG D LR+GMG GSICIT
Sbjct: 290 DSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICIT 349
Query: 328 QEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANVAMLGSMIAGT 387
QEV+ACGRPQ TA+YKVA YA GVP +ADGG++ VG V KALA+GA+ M+GS++A T
Sbjct: 350 QEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAAT 409
Query: 388 SETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGVAGAVLDKGSV 447
+E PGEYFF DG+RLK YRGMGS+DAM + S KRY SE + +++AQGV+G++ DKGS+
Sbjct: 410 TEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSI 469
Query: 448 LKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAVHSLHHYERKL 507
K + Y+ G+Q QDIG S +R +Y G++ F +RT++AQ EG VH LH YE++L
Sbjct: 470 QKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRL 529
Query: 508 F 508
+
Sbjct: 530 Y 530
>ref|YP_001665693.1| response regulator receiver protein [Thermoanaerobacter
pseudethanolicus ATCC 33223]
ref|YP_001662158.1| response regulator receiver protein [Thermoanaerobacter sp. X514]
gb|ABY91822.1| response regulator receiver protein [Thermoanaerobacter sp. X514]
gb|ABY95357.1| response regulator receiver protein [Thermoanaerobacter
pseudethanolicus ATCC 33223]
Length = 484
Score = 852 bits (2202), Expect = 0.0, Method: Composition-based stats.
Identities = 181/483 (37%), Positives = 282/483 (58%), Gaps = 12/483 (2%)
Query: 18 EELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARA 77
EE F ++GL+F+D +++P D V++ + TK I L++PL+S+ MDTVTES +A A
Sbjct: 2 EEKFVKEGLTFDDVLLIPAKSDVLPKDVDLKTKLTKKITLNIPLMSAGMDTVTESKLAIA 61
Query: 78 MALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISG 137
+A GGIGVIH N ++E+QA V VK +G I P S++PD + + + ISG
Sbjct: 62 IAREGGIGVIHKNMSIERQALEVDKVKRSEHGVITDPFSLTPDHTIKDAAELMARYKISG 121
Query: 138 ILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNR 197
+ +T D KL+GI+ +DI F D P+ + MT+ +N+ LEEA +L +
Sbjct: 122 VPIT----VDSKLVGIITNRDIRFEDDLDKPIREVMTK-DNLVTAPPGTTLEEARQILKK 176
Query: 198 SRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAAL 257
+ LP++++ + + L + +D +A ++PN++ D G LL AAA + RV AL
Sbjct: 177 HKIEKLPLVDENNVLKGLITIKDIEKAVEFPNAAKDSKGRLLVAAAVGVGKDMMDRVKAL 236
Query: 258 SEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRI 317
EAG+D +V+D++ G++ + + +K+ YP L+++AGNV T + ++LI+ GAD +++
Sbjct: 237 VEAGVDAIVIDTAHGHSKGVLEAVSKIKEKYPDLQLIAGNVATAEATRDLIERGADCVKV 296
Query: 318 GMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANV 377
G+G GSIC T+ + G PQ TAIY A+ A G+P +ADGG++ GD+ KA+A GA+V
Sbjct: 297 GIGPGSICTTRVIAGVGVPQITAIYDCAQEADKYGIPIIADGGIKYSGDIVKAIAAGASV 356
Query: 378 AMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGV 437
MLGS+ AGT E+PGE G K YRGMGS+ AM +G S RY E+ T V +GV
Sbjct: 357 VMLGSLFAGTEESPGEIEIYQGRSYKVYRGMGSLGAMKEG--SSDRYFQEDVTKFVPEGV 414
Query: 438 AGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAV 497
G V KG + + + + GL+ G + + +R K F + T +E
Sbjct: 415 EGRVPYKGPLKETVYQLVGGLRAGMGYCGVRNIEELRTK-----TKFIKITQAGLTESHP 469
Query: 498 HSL 500
H +
Sbjct: 470 HDI 472
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|YP_001665693.1| response regulator receiver protein [Th... 890 0.0
ref|YP_001180491.1| inosine-5'-monophosphate dehydrogenase ... 889 0.0
ref|NP_622249.1| IMP dehydrogenase/GMP reductase [Thermoana... 888 0.0
ref|XP_001252299.1| PREDICTED: inosine monophosphate dehydr... 886 0.0
ref|ZP_02914844.1| inosine-5'-monophosphate dehydrogenase [... 883 0.0
ref|NP_000874.2| inosine monophosphate dehydrogenase 1 isof... 880 0.0
ref|NP_001096075.1| inosine monophosphate dehydrogenase 1 i... 880 0.0
ref|YP_145862.1| inositol-5-monophosphate dehydrogenase [Ge... 879 0.0
ref|NP_899066.1| inosine monophosphate dehydrogenase 1 isof... 879 0.0
gb|EAW83652.1| IMP (inosine monophosphate) dehydrogenase 1,... 878 0.0
sp|P20839|IMDH1_HUMAN Inosine-5'-monophosphate dehydrogenas... 877 0.0
ref|NP_001071309.1| inosine monophosphate dehydrogenase 1 [... 877 0.0
ref|ZP_01667581.1| inosine-5'-monophosphate dehydrogenase [... 877 0.0
gb|EDL13789.1| inosine 5'-phosphate dehydrogenase 1, isofor... 877 0.0
ref|YP_360021.1| inosine-5'-monophosphate dehydrogenase [Ca... 875 0.0
emb|CAA39204.1| IMP dehydrogenase [Bacillus subtilis] 874 0.0
ref|NP_240886.1| inositol-5-monophosphate dehydrogenase [Ba... 874 0.0
ref|YP_001124141.1| inositol-5-monophosphate dehydrogenase ... 873 0.0
pdb|1JCN|A Chain A, Binary Complex Of Human Type-I Inosine ... 873 0.0
ref|YP_076743.1| inosine-5'-monophosphate dehydrogenase [Sy... 871 0.0
emb|CAK04261.1| novel protein similar to vertebrate IMP (in... 871 0.0
gb|EAW83649.1| IMP (inosine monophosphate) dehydrogenase 1,... 870 0.0
gb|EDM15208.1| IMP (inosine monophosphate) dehydrogenase 1 ... 870 0.0
ref|YP_001695789.1| Inosine-5'-monophosphate dehydrogenase ... 870 0.0
ref|NP_035959.2| inosine 5'-phosphate dehydrogenase 1 [Mus ... 869 0.0
ref|XP_001372080.1| PREDICTED: similar to Inosine monophosp... 869 0.0
ref|NP_387890.1| inositol-5-monophosphate dehydrogenase [Ba... 869 0.0
ref|YP_545250.1| inosine-5'-monophosphate dehydrogenase [Me... 868 0.0
ref|ZP_01725067.1| inositol-5-monophosphate dehydrogenase [... 868 0.0
ref|YP_001373379.1| inosine-5'-monophosphate dehydrogenase ... 868 0.0
dbj|BAA89464.1| IMPDH [Bacillus cereus] 866 0.0
ref|YP_001419688.1| GuaB [Bacillus amyloliquefaciens FZB42]... 865 0.0
ref|NP_001080792.1| inosine 5'-phosphate dehydrogenase 1 [X... 865 0.0
ref|NP_001017283.1| IMP (inosine monophosphate) dehydrogena... 865 0.0
ref|ZP_02079836.1| hypothetical protein CLOLEP_01281 [Clost... 864 0.0
ref|NP_976337.1| inositol-5-monophosphate dehydrogenase [Ba... 864 0.0
dbj|BAA88235.1| IMP dehydrogenase [Bacillus cereus] 864 0.0
ref|ZP_01967358.1| hypothetical protein RUMTOR_00905 [Rumin... 864 0.0
ref|ZP_02234042.1| hypothetical protein DORFOR_00900 [Dorea... 864 0.0
gb|AAA36114.1| IMP dehydrogenase type 1 (EC 1.1.1.205) 863 0.0
ref|NP_829917.1| inositol-5-monophosphate dehydrogenase [Ba... 863 0.0
ref|YP_034368.1| inositol-5-monophosphate dehydrogenase [Ba... 863 0.0
ref|YP_002769495.1| inosine-5'-monophosphate dehydrogenase ... 863 0.0
ref|NP_842579.1| inositol-5-monophosphate dehydrogenase [Ba... 862 0.0
ref|YP_173515.1| inositol-5-monophosphate dehydrogenase [Ba... 862 0.0
ref|ZP_02039215.1| hypothetical protein BACCAP_04867 [Bacte... 862 0.0
sp|P50096|IMDH1_MOUSE Inosine-5'-monophosphate dehydrogenas... 861 0.0
ref|ZP_00743847.1| Inosine-5'-monophosphate dehydrogenase [... 861 0.0
ref|NP_001002177.1| hypothetical protein LOC431724 [Danio r... 861 0.0
ref|YP_001642905.1| inosine-5'-monophosphate dehydrogenase ... 861 0.0
ref|NP_001014391.1| hypothetical protein LOC338306 [Danio r... 861 0.0
ref|ZP_00390434.1| COG0516: IMP dehydrogenase/GMP reductase... 861 0.0
ref|YP_001680969.1| inosine-5'-monophosphate dehydrogenase ... 861 0.0
ref|ZP_01173811.1| inositol-5-monophosphate dehydrogenase [... 861 0.0
ref|YP_077291.1| inosine-monophosphate dehydrogenase [Bacil... 860 0.0
ref|ZP_02263522.1| inositol-5-monophosphate dehydrogenase [... 860 0.0
ref|YP_001512091.1| inosine-5'-monophosphate dehydrogenase ... 860 0.0
ref|ZP_01190168.1| IMP dehydrogenase [Halothermothrix oreni... 859 0.0
gb|EAW64946.1| hCG2002013, isoform CRA_a [Homo sapiens] 859 0.0
ref|XP_001494600.1| PREDICTED: similar to hCG2002013 [Equus... 858 0.0
gb|EEK04434.1| inosine-5'-monophosphate dehydrogenase [Alic... 858 0.0
ref|ZP_01995666.1| hypothetical protein DORLON_01661 [Dorea... 858 0.0
ref|NP_349307.1| inositol-5-monophosphate dehydrogenase [Cl... 858 0.0
gb|AAN87502.1| Inosine-5'-monophosphate dehydrogenase [Heli... 857 0.0
ref|NP_782942.1| inositol-5-monophosphate dehydrogenase [Cl... 857 0.0
ref|ZP_02206927.1| hypothetical protein COPEUT_01719 [Copro... 856 0.0
ref|YP_001717214.1| inosine-5'-monophosphate dehydrogenase ... 856 0.0
ref|XP_001110855.1| PREDICTED: inosine monophosphate dehydr... 856 0.0
emb|CAI21140.1| novel protein similar to vertebrate IMP (in... 856 0.0
ref|ZP_02862590.1| hypothetical protein ANASTE_01809 [Anaer... 856 0.0
ref|ZP_02041332.1| hypothetical protein RUMGNA_02099 [Rumin... 856 0.0
ref|NP_001025772.1| inosine monophosphate dehydrogenase 2 [... 856 0.0
ref|ZP_02089056.1| hypothetical protein CLOBOL_06625 [Clost... 855 0.0
ref|ZP_02429849.1| hypothetical protein CLOSCI_00052 [Clost... 855 0.0
ref|YP_001485759.1| IMP dehydrogenase [Bacillus pumilus SAF... 855 0.0
ref|ZP_01963621.1| hypothetical protein RUMOBE_01343 [Rumin... 855 0.0
ref|YP_429965.1| inosine-5'-monophosphate dehydrogenase [Mo... 855 0.0
ref|ZP_02850469.1| inosine-5'-monophosphate dehydrogenase [... 854 0.0
ref|NP_214389.1| inosine monophosphate dehydrogenase [Aquif... 854 0.0
ref|NP_000875.2| inosine monophosphate dehydrogenase 2 [Hom... 854 0.0
ref|XP_850933.1| PREDICTED: similar to inosine 5-phosphate ... 854 0.0
gb|ACB54657.1| inosine 5' monophosphate dehydrogenase [Paen... 854 0.0
emb|CAQ13978.1| IMP (inosine monophosphate) dehydrogenase 2... 854 0.0
sp|P12269|IMDH2_CRIGR Inosine-5'-monophosphate dehydrogenas... 853 0.0
ref|ZP_02025103.1| hypothetical protein EUBVEN_00328 [Eubac... 853 0.0
ref|YP_095750.1| inosine-5'-monophosphate dehydrogenase [Le... 853 0.0
ref|YP_001250469.1| inosine-5'-monophosphate dehydrogenase ... 853 0.0
ref|YP_436057.1| inosine-5'-monophosphate dehydrogenase [Ha... 853 0.0
ref|NP_900973.1| inositol-5-monophosphate dehydrogenase [Ch... 853 0.0
ref|NP_001029588.1| IMP (inosine monophosphate) dehydrogena... 852 0.0
ref|NP_035960.2| inosine 5'-phosphate dehydrogenase 2 [Mus ... 852 0.0
ref|YP_878931.1| inositol-5-monophosphate dehydrogenase [Cl... 852 0.0
ref|XP_001367707.1| PREDICTED: similar to hCG2002013, [Mono... 852 0.0
ref|YP_127026.1| hypothetical protein lpl1687 [Legionella p... 852 0.0
gb|AAA39311.1| IMP dehydrogenase (EC 1.2.1.14) 851 0.0
ref|NP_958872.1| inosine monophosphate dehydrogenase 2 [Dan... 851 0.0
ref|ZP_01552004.1| IMP dehydrogenase [Methylophilales bacte... 851 0.0
ref|XP_001478203.1| PREDICTED: similar to Inosine 5-phospha... 851 0.0
gb|AAA36112.1| inosine-5'-monophosphate dehydrogenase (EC 1... 851 0.0
ref|YP_001318789.1| inosine-5'-monophosphate dehydrogenase ... 851 0.0
ref|ZP_02438314.1| hypothetical protein CLOSS21_00765 [Clos... 851 0.0
dbj|BAE30628.1| unnamed protein product [Mus musculus] 851 0.0
ref|ZP_02093569.1| hypothetical protein PEPMIC_00320 [Pepto... 851 0.0
ref|XP_516452.2| PREDICTED: inosine monophosphate dehydroge... 851 0.0
ref|XP_001089341.1| PREDICTED: similar to inosine monophosp... 851 0.0
ref|ZP_02356071.1| inositol-5-monophosphate dehydrogenase [... 851 0.0
dbj|BAE25403.1| unnamed protein product [Mus musculus] 850 0.0
emb|CAI45968.1| hypothetical protein [Homo sapiens] 850 0.0
ref|ZP_02074678.1| hypothetical protein CLOL250_01453 [Clos... 849 0.0
ref|ZP_01862180.1| inositol-5-monophosphate dehydrogenase [... 849 0.0
ref|NP_001082410.1| similar to inosine 5'-phosphate dehydro... 849 0.0
ref|ZP_00946937.1| Inosine-5'-monophosphate dehydrogenase [... 849 0.0
ref|NP_519550.1| inositol-5-monophosphate dehydrogenase [Ra... 849 0.0
ref|NP_690931.1| inosine-5'-monophosphate dehydrogenase [Oc... 849 0.0
dbj|BAD18464.1| unnamed protein product [Homo sapiens] 849 0.0
gb|AAA20181.1| IMP dehydrogenase 849 0.0
ref|XP_862835.1| PREDICTED: similar to Inosine-5-monophosph... 848 0.0
ref|YP_001857542.1| inosine-5'-monophosphate dehydrogenase ... 848 0.0
ref|YP_001560380.1| inosine-5'-monophosphate dehydrogenase ... 848 0.0
ref|XP_001501637.1| PREDICTED: hypothetical protein [Equus ... 847 0.0
ref|NP_954530.1| inosine monophosphate dehydrogenase 2 [Rat... 847 0.0
ref|YP_001188966.1| inositol-5-monophosphate dehydrogenase ... 847 0.0
ref|ZP_02620682.2| inosine-5'-monophosphate dehydrogenase [... 847 0.0
ref|ZP_02993260.1| hypothetical protein CLOSPO_00303 [Clost... 847 0.0
ref|XP_850999.1| PREDICTED: similar to inosine monophosphat... 847 0.0
ref|ZP_02002658.1| Inosine-5'-monophosphate dehydrogenase [... 847 0.0
ref|YP_001919809.1| inosine-5'-monophosphate dehydrogenase ... 847 0.0
ref|ZP_02950650.1| inosine-5'-monophosphate dehydrogenase [... 846 0.0
ref|ZP_01043759.1| inositol-5-monophosphate dehydrogenase [... 846 0.0
gb|EEH96603.1| inositol-monophosphate dehydrogenase [Clostr... 846 0.0
ref|YP_001393867.1| GuaB [Clostridium kluyveri DSM 555] >gi... 846 0.0
ref|XP_533835.2| PREDICTED: similar to inosine 5-phosphate ... 846 0.0
ref|ZP_01313162.1| inosine-5'-monophosphate dehydrogenase [... 846 0.0
ref|XP_862898.1| PREDICTED: similar to Inosine-5-monophosph... 846 0.0
ref|XP_862874.1| PREDICTED: similar to Inosine-5-monophosph... 845 0.0
ref|ZP_01516974.1| inosine-5'-monophosphate dehydrogenase [... 845 0.0
ref|YP_001211868.1| hypothetical protein PTH_1318 [Pelotoma... 845 0.0
ref|YP_356636.1| inosine-5'-monophosphate dehydrogenase [Pe... 845 0.0
ref|ZP_02379271.1| inositol-5-monophosphate dehydrogenase [... 844 0.0
ref|NP_001008066.1| IMP (inosine monophosphate) dehydrogena... 844 0.0
ref|YP_001884623.1| inosine-5'-monophosphate dehydrogenase ... 844 0.0
ref|YP_001430358.1| inosine-5'-monophosphate dehydrogenase ... 844 0.0
ref|YP_001599217.1| inosine-5'-monophosphate dehydrogenase ... 844 0.0
ref|YP_001898882.1| inosine-5'-monophosphate dehydrogenase ... 843 0.0
ref|ZP_02008991.1| inosine-5'-monophosphate dehydrogenase [... 843 0.0
ref|ZP_03906688.1| inosine-5'-monophosphate dehydrogenase [... 842 0.0
ref|ZP_01892873.1| inosine-5'-monophosphate dehydrogenase [... 842 0.0
ref|XP_001505397.1| PREDICTED: similar to hCG2002013 [Ornit... 842 0.0
ref|ZP_02616743.1| inosine-5'-monophosphate dehydrogenase [... 842 0.0
ref|NP_001083990.1| inosine 5'-phosphate dehydrogenase 2 [X... 842 0.0
ref|YP_001392641.1| inosine-5'-monophosphate dehydrogenase ... 842 0.0
gb|EEJ80041.1| inosine-5'-monophosphate dehydrogenase [Kang... 842 0.0
ref|NP_274226.1| inositol-5-monophosphate dehydrogenase [Ne... 842 0.0
ref|YP_001113252.1| inosine-5'-monophosphate dehydrogenase ... 842 0.0
ref|ZP_03854594.1| inosine-5'-monophosphate dehydrogenase [... 842 0.0
ref|YP_296065.1| inositol-5-monophosphate dehydrogenase [Ra... 842 0.0
ref|YP_001255780.1| inositol-5-monophosphate dehydrogenase ... 842 0.0
ref|YP_975144.1| inositol-5-monophosphate dehydrogenase [Ne... 842 0.0
ref|ZP_01739391.1| inosine-5'-monophosphate dehydrogenase [... 842 0.0
ref|ZP_00979930.1| COG0516: IMP dehydrogenase/GMP reductase... 841 0.0
ref|ZP_02691687.1| inosine-5'-monophosphate dehydrogenase [... 841 0.0
ref|YP_001782919.1| inosine-5'-monophosphate dehydrogenase ... 841 0.0
ref|YP_001119735.1| inositol-5-monophosphate dehydrogenase ... 841 0.0
ref|ZP_01112019.1| inositol-5-monophosphate dehydrogenase [... 841 0.0
ref|YP_726498.1| inositol-5-monophosphate dehydrogenase [Ra... 841 0.0
ref|YP_001788612.1| inosine-5'-monophosphate dehydrogenase ... 841 0.0
ref|ZP_02177021.1| inosine monophosphate dehydrogenase [Hyd... 841 0.0
ref|NP_284115.1| inositol-5-monophosphate dehydrogenase [Ne... 840 0.0
emb|CAO86108.1| inosine-5'-monophosphate dehydrogenase [Clo... 840 0.0
emb|CAG03265.1| unnamed protein product [Tetraodon nigrovir... 840 0.0
ref|YP_411895.1| inosine-5'-monophosphate dehydrogenase [Ni... 840 0.0
ref|ZP_03980672.1| IMP dehydrogenase [Enterococcus faecium ... 840 0.0
ref|XP_001110813.1| PREDICTED: inosine monophosphate dehydr... 840 0.0
ref|YP_526933.1| IMP dehydrogenase [Saccharophagus degradan... 840 0.0
ref|YP_369539.1| inositol-5-monophosphate dehydrogenase [Bu... 840 0.0
ref|YP_001797406.1| inosine-5'-monophosphate dehydrogenase ... 839 0.0
ref|YP_971702.1| inosine-5'-monophosphate dehydrogenase [Ac... 839 0.0
ref|ZP_01115483.1| inositol-5-monophosphate dehydrogenase [... 839 0.0
ref|YP_753603.1| IMP dehydrogenase [Syntrophomonas wolfei s... 839 0.0
ref|XP_862810.1| PREDICTED: similar to inosine 5-phosphate ... 839 0.0
ref|YP_662680.1| inositol-5-monophosphate dehydrogenase [Ps... 838 0.0
ref|NP_953244.1| inosine-5'-monophosphate dehydrogenase [Ge... 838 0.0
ref|YP_001634245.1| inosine-5'-monophosphate dehydrogenase ... 838 0.0
ref|ZP_02910335.1| inosine-5'-monophosphate dehydrogenase [... 838 0.0
ref|ZP_04009332.1| inositol-5-monophosphate dehydrogenase [... 838 0.0
ref|ZP_00604372.1| IMP dehydrogenase [Enterococcus faecium ... 838 0.0
ref|YP_583613.1| inositol-5-monophosphate dehydrogenase [Ra... 837 0.0
ref|YP_001765294.1| inosine-5'-monophosphate dehydrogenase ... 837 0.0
ref|YP_773914.1| inositol-5-monophosphate dehydrogenase [Bu... 836 0.0
ref|ZP_02478246.1| inosine-5'-monophosphate dehydrogenase [... 836 0.0
ref|YP_741857.1| inosine-5'-monophosphate dehydrogenase [Al... 836 0.0
ref|YP_958999.1| inosine-5'-monophosphate dehydrogenase [Ma... 836 0.0
ref|ZP_02185622.1| inositol-5-monophosphate dehydrogenase [... 836 0.0
ref|YP_342662.1| IMP dehydrogenase [Nitrosococcus oceani AT... 836 0.0
ref|YP_718630.1| inositol-5-monophosphate dehydrogenase [Ha... 836 0.0
ref|YP_523537.1| inosine-5'-monophosphate dehydrogenase [Rh... 835 0.0
ref|YP_001275063.1| inosine-5'-monophosphate dehydrogenase ... 835 0.0
ref|YP_108726.1| inositol-5-monophosphate dehydrogenase [Bu... 835 0.0
ref|YP_001449330.1| inosine-5'-monophosphate dehydrogenase ... 835 0.0
ref|YP_001784083.1| inosine-5'-monophosphate dehydrogenase ... 835 0.0
ref|ZP_03992373.1| IMP dehydrogenase [Oribacterium sinus F0... 834 0.0
ref|YP_207925.1| inositol-5-monophosphate dehydrogenase [Ne... 834 0.0
ref|YP_001036281.1| inositol-5-monophosphate dehydrogenase ... 834 0.0
ref|YP_001875186.1| inosine-5'-monophosphate dehydrogenase ... 834 0.0
ref|YP_536339.1| inositol-5-monophosphate dehydrogenase [La... 833 0.0
ref|ZP_02883330.1| inosine-5'-monophosphate dehydrogenase [... 833 0.0
ref|YP_442580.1| inositol-5-monophosphate dehydrogenase [Bu... 833 0.0
ref|NP_001102089.1| inosine 5'-phosphate dehydrogenase 1 [R... 833 0.0
ref|YP_142341.1| inositol-5-monophosphate dehydrogenase [St... 832 0.0
ref|NP_346636.1| inositol-5-monophosphate dehydrogenase [St... 832 0.0
gb|EDL13788.1| inosine 5'-phosphate dehydrogenase 1, isofor... 832 0.0
ref|YP_001916216.1| inosine-5'-monophosphate dehydrogenase ... 832 0.0
gb|AAX77966.1| unknown protein [synthetic construct] 832 0.0
ref|YP_559301.1| inositol-5-monophosphate dehydrogenase [Bu... 832 0.0
ref|YP_901677.1| inosine-5'-monophosphate dehydrogenase [Pe... 832 0.0
ref|ZP_01817819.1| inositol-5-monophosphate dehydrogenase [... 832 0.0
ref|ZP_02211058.1| hypothetical protein CLOBAR_00656 [Clost... 832 0.0
ref|ZP_02288166.1| inosine-5'-monophosphate dehydrogenase [... 832 0.0
ref|ZP_02711714.1| inosine-5'-monophosphate dehydrogenase [... 831 0.0
ref|YP_001896051.1| inosine-5'-monophosphate dehydrogenase ... 831 0.0
ref|YP_385243.1| IMP dehydrogenase [Geobacter metallireduce... 831 0.0
ref|YP_002796618.1| GuaB [Laribacter hongkongensis HLHK9] >... 831 0.0
ref|ZP_02688926.1| inosine-5'-monophosphate dehydrogenase [... 831 0.0
ref|NP_472228.1| guaB [Listeria innocua Clip11262] >gi|1680... 831 0.0
ref|ZP_02841449.1| inosine-5'-monophosphate dehydrogenase [... 831 0.0
ref|YP_170270.1| Inosine-5-monophosphate dehydrogenase [Fra... 830 0.0
ref|ZP_02919722.1| hypothetical protein STRINF_00574 [Strep... 830 0.0
ref|YP_001199549.1| inositol-5-monophosphate dehydrogenase ... 829 0.0
ref|YP_001543976.1| inosine-5'-monophosphate dehydrogenase ... 829 0.0
ref|YP_140425.1| inositol-5-monophosphate dehydrogenase [St... 829 0.0
ref|ZP_02468286.1| inositol-5-monophosphate dehydrogenase [... 829 0.0
ref|YP_749828.1| inositol-5-monophosphate dehydrogenase [Sh... 829 0.0
ref|ZP_02992456.1| inosine-5'-monophosphate dehydrogenase [... 829 0.0
ref|NP_689144.1| inositol-5-monophosphate dehydrogenase [St... 828 0.0
ref|YP_850902.1| inosine-5'-monophosphate dehydrogenase [Li... 828 0.0
ref|ZP_00784476.1| inosine-5'-monophosphate dehydrogenase [... 828 0.0
ref|YP_001501175.1| inosine-5'-monophosphate dehydrogenase ... 828 0.0
ref|YP_001930992.1| inosine-5'-monophosphate dehydrogenase ... 828 0.0
ref|YP_339176.1| inositol-5-monophosphate dehydrogenase [Ps... 827 0.0
ref|YP_001812513.1| inosine-5'-monophosphate dehydrogenase ... 827 0.0
ref|ZP_01388248.1| inosine-5'-monophosphate dehydrogenase [... 827 0.0
ref|YP_001676882.1| Malate dehydrogenase [Francisella philo... 827 0.0
ref|YP_302413.1| IMP dehydrogenase [Staphylococcus saprophy... 827 0.0
ref|ZP_02444933.1| hypothetical protein ANACOL_04268 [Anaer... 827 0.0
ref|ZP_01132948.1| inositol-5-monophosphate dehydrogenase [... 827 0.0
ref|ZP_01774642.1| inosine-5'-monophosphate dehydrogenase [... 827 0.0
ref|YP_603464.1| inositol-5-monophosphate dehydrogenase [St... 827 0.0
ref|YP_001891952.1| IMP dehydrogenase/GMP reductase [Franci... 827 0.0
ref|YP_514129.1| Inosine-5-monophosphate dehydrogenase [Fra... 827 0.0
ref|YP_001409640.1| inosine-5'-monophosphate dehydrogenase ... 827 0.0
ref|NP_765903.1| inositol-monophosphate dehydrogenase [Stap... 827 0.0
ref|NP_722440.1| inositol-5-monophosphate dehydrogenase [St... 826 0.0
ref|ZP_02420021.1| hypothetical protein ANACAC_02623 [Anaer... 826 0.0
ref|NP_230416.1| inositol-5-monophosphate dehydrogenase [Vi... 826 0.0
ref|NP_270113.1| inositol-5-monophosphate dehydrogenase [St... 826 0.0
ref|ZP_01448897.1| inositol-5-monophosphate dehydrogenase [... 826 0.0
ref|YP_112825.1| inosine-5'-monophosphate dehydrogenase [Me... 826 0.0
gb|EAZ50737.1| inosine-5`-monophosphate dehydrogenase [Vibr... 826 0.0
ref|ZP_01480506.1| hypothetical protein VchoM_02000254 [Vib... 826 0.0
ref|ZP_01486980.1| hypothetical protein VchoV5_02000332 [Vi... 826 0.0
ref|NP_665661.1| inositol-5-monophosphate dehydrogenase [St... 826 0.0
ref|YP_001280158.1| inosine-5'-monophosphate dehydrogenase ... 825 0.0
ref|YP_391882.1| inosine-5'-monophosphate dehydrogenase [Th... 825 0.0
ref|NP_840196.1| guaB; inosine-5'-monophosphate dehydrogena... 825 0.0
ref|YP_001231858.1| inosine-5'-monophosphate dehydrogenase ... 825 0.0
ref|YP_001156201.1| inositol-5-monophosphate dehydrogenase ... 824 0.0
ref|YP_087966.1| inositol-5-monophosphate dehydrogenase [Ma... 824 0.0
ref|YP_247942.1| inositol-5-monophosphate dehydrogenase [Ha... 824 0.0
ref|NP_933568.1| inositol-5-monophosphate dehydrogenase [Vi... 824 0.0
ref|NP_759415.1| inositol-5-monophosphate dehydrogenase [Vi... 824 0.0
ref|ZP_01788198.1| inositol-5-monophosphate dehydrogenase [... 824 0.0
ref|NP_229148.1| inosine-5'-monophosphate dehydrogenase [Th... 824 0.0
ref|YP_001353724.1| inosine-5'-monophosphate dehydrogenase ... 824 0.0
ref|YP_001739509.1| inosine-5'-monophosphate dehydrogenase ... 823 0.0
ref|NP_370914.1| inositol-monophosphate dehydrogenase [Stap... 823 0.0
pdb|1VRD|A Chain A, Crystal Structure Of Inosine-5'-Monopho... 823 0.0
ref|ZP_00591540.1| IMP dehydrogenase [Prosthecochloris aest... 823 0.0
ref|YP_001306807.1| inosine-5'-monophosphate dehydrogenase ... 823 0.0
ref|YP_912073.1| inosine-5'-monophosphate dehydrogenase [Ch... 822 0.0
gb|EDN73348.1| IMP dehydrogenase [Mannheimia haemolytica PH... 822 0.0
ref|ZP_03988119.1| inositol-monophosphate dehydrogenase [St... 822 0.0
ref|NP_245232.1| inositol-5-monophosphate dehydrogenase [Pa... 822 0.0
ref|YP_001031590.1| inositol-5-monophosphate dehydrogenase ... 822 0.0
ref|NP_266376.1| inositol-5-monophosphate dehydrogenase [La... 822 0.0
gb|EDN57672.1| inosine-5'-monophosphate dehydrogenase [Vibr... 822 0.0
ref|YP_001099659.1| IMP dehydrogeanse [Herminiimonas arseni... 822 0.0
ref|ZP_00156063.1| COG0516: IMP dehydrogenase/GMP reductase... 821 0.0
ref|YP_786091.1| inosine-5'-monophosphate dehydrogenase [Bo... 821 0.0
ref|YP_285544.1| IMP dehydrogenase [Dechloromonas aromatica... 821 0.0
ref|NP_645183.1| inositol-monophosphate dehydrogenase [Stap... 821 0.0
ref|ZP_01521990.1| inosine-5'-monophosphate dehydrogenase [... 821 0.0
ref|NP_796995.1| inositol-5-monophosphate dehydrogenase [Vi... 821 0.0
ref|NP_642605.1| inositol-5-monophosphate dehydrogenase [Xa... 821 0.0
ref|ZP_01991209.1| inosine-5'-monophosphate dehydrogenase [... 820 0.0
ref|ZP_01128723.1| inosine-5'-monophosphate dehydrogenase [... 820 0.0
ref|YP_001759940.1| inosine-5'-monophosphate dehydrogenase ... 820 0.0
ref|YP_254498.1| inositol-monophosphate dehydrogenase [Stap... 820 0.0
ref|YP_001053300.1| inositol-5-monophosphate dehydrogenase ... 820 0.0
ref|ZP_00986688.1| COG0516: IMP dehydrogenase/GMP reductase... 819 0.0
ref|YP_996032.1| inosine-5'-monophosphate dehydrogenase [Ve... 819 0.0
Sequences not found previously or not previously below threshold:
>ref|YP_001665693.1| response regulator receiver protein [Thermoanaerobacter
pseudethanolicus ATCC 33223]
ref|YP_001662158.1| response regulator receiver protein [Thermoanaerobacter sp. X514]
gb|ABY91822.1| response regulator receiver protein [Thermoanaerobacter sp. X514]
gb|ABY95357.1| response regulator receiver protein [Thermoanaerobacter
pseudethanolicus ATCC 33223]
Length = 484
Score = 890 bits (2301), Expect = 0.0, Method: Composition-based stats.
Identities = 181/483 (37%), Positives = 282/483 (58%), Gaps = 12/483 (2%)
Query: 18 EELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARA 77
EE F ++GL+F+D +++P D V++ + TK I L++PL+S+ MDTVTES +A A
Sbjct: 2 EEKFVKEGLTFDDVLLIPAKSDVLPKDVDLKTKLTKKITLNIPLMSAGMDTVTESKLAIA 61
Query: 78 MALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISG 137
+A GGIGVIH N ++E+QA V VK +G I P S++PD + + + ISG
Sbjct: 62 IAREGGIGVIHKNMSIERQALEVDKVKRSEHGVITDPFSLTPDHTIKDAAELMARYKISG 121
Query: 138 ILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNR 197
+ +T D KL+GI+ +DI F D P+ + MT+ +N+ LEEA +L +
Sbjct: 122 VPIT----VDSKLVGIITNRDIRFEDDLDKPIREVMTK-DNLVTAPPGTTLEEARQILKK 176
Query: 198 SRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAAL 257
+ LP++++ + + L + +D +A ++PN++ D G LL AAA + RV AL
Sbjct: 177 HKIEKLPLVDENNVLKGLITIKDIEKAVEFPNAAKDSKGRLLVAAAVGVGKDMMDRVKAL 236
Query: 258 SEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRI 317
EAG+D +V+D++ G++ + + +K+ YP L+++AGNV T + ++LI+ GAD +++
Sbjct: 237 VEAGVDAIVIDTAHGHSKGVLEAVSKIKEKYPDLQLIAGNVATAEATRDLIERGADCVKV 296
Query: 318 GMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANV 377
G+G GSIC T+ + G PQ TAIY A+ A G+P +ADGG++ GD+ KA+A GA+V
Sbjct: 297 GIGPGSICTTRVIAGVGVPQITAIYDCAQEADKYGIPIIADGGIKYSGDIVKAIAAGASV 356
Query: 378 AMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGV 437
MLGS+ AGT E+PGE G K YRGMGS+ AM +G S RY E+ T V +GV
Sbjct: 357 VMLGSLFAGTEESPGEIEIYQGRSYKVYRGMGSLGAMKEG--SSDRYFQEDVTKFVPEGV 414
Query: 438 AGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAV 497
G V KG + + + + GL+ G + + +R K F + T +E
Sbjct: 415 EGRVPYKGPLKETVYQLVGGLRAGMGYCGVRNIEELRTK-----TKFIKITQAGLTESHP 469
Query: 498 HSL 500
H +
Sbjct: 470 HDI 472
>ref|YP_001180491.1| inosine-5'-monophosphate dehydrogenase [Caldicellulosiruptor
saccharolyticus DSM 8903]
gb|ABP67300.1| inosine-5'-monophosphate dehydrogenase [Caldicellulosiruptor
saccharolyticus DSM 8903]
Length = 488
Score = 889 bits (2299), Expect = 0.0, Method: Composition-based stats.
Identities = 184/484 (38%), Positives = 283/484 (58%), Gaps = 12/484 (2%)
Query: 18 EELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARA 77
++ ++ L+F+D +++P + + V+VS T+ I L++PL+S+ MDTVTES MA A
Sbjct: 4 KDKVIKEALTFDDVLLVPQYSEVLPKDVDVSTYLTRTIKLNIPLMSAGMDTVTESRMAIA 63
Query: 78 MALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISG 137
+A GGIGVIH N T+E+QA V VK +G I+ P +SP+ + + ++ ISG
Sbjct: 64 IAREGGIGVIHKNMTIEEQASEVDKVKRSEHGVIVDPFYLSPENKIYEAMELMAKYRISG 123
Query: 138 ILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNR 197
+ +T +GKL+GI+ +DI F D S P+ + MT N+ + I LEEA +++ +
Sbjct: 124 VPIT----VNGKLVGIITNRDIRFETDYSKPIKEVMTSS-NLITAKEGITLEEAKEIMKK 178
Query: 198 SRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAAL 257
+ LP+++D+ + L + +D +A YPN++ D G LLCAAA + + RV AL
Sbjct: 179 HKIEKLPIVDDEGNLKGLITIKDIEKAVKYPNAAKDSRGRLLCAAAVGVSKDTEQRVEAL 238
Query: 258 SEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRI 317
+A +DV+V+D++ G++ + ++ +K YP+L+VVAGN+ T + A +LI AGAD +++
Sbjct: 239 VKAQVDVIVVDTAHGHSKGVIETVKKIKAKYPNLQVVAGNIATAEAAYDLIKAGADCIKV 298
Query: 318 GMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANV 377
G+G GSIC T+ V G PQ TAI A A G+P +ADGG+R GD+ KALA GA+V
Sbjct: 299 GIGPGSICTTRVVAGVGVPQITAIMDCAEVAKEYGIPVIADGGIRYSGDITKALAAGADV 358
Query: 378 AMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGV 437
M+GS+ AG E+PGE G R K YRGMGS+ AM G S RY E+ + V +GV
Sbjct: 359 VMIGSLFAGCEESPGECEIYQGRRFKVYRGMGSLSAMKAG--SKDRYFQEDASKLVPEGV 416
Query: 438 AGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAV 497
G V KG + + + GL+ G + ++EK F + T E
Sbjct: 417 EGRVPYKGPLEDTVFQLVGGLKAGMGYCGARTIKELQEKA-----KFVKITQAGVRESHP 471
Query: 498 HSLH 501
H ++
Sbjct: 472 HDIY 475
>ref|NP_622249.1| IMP dehydrogenase/GMP reductase [Thermoanaerobacter tengcongensis
MB4]
gb|AAM23853.1| IMP dehydrogenase/GMP reductase [Thermoanaerobacter tengcongensis
MB4]
Length = 484
Score = 888 bits (2296), Expect = 0.0, Method: Composition-based stats.
Identities = 179/483 (37%), Positives = 281/483 (58%), Gaps = 12/483 (2%)
Query: 18 EELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARA 77
E+ F ++GL+F+D +++P D V++ + TK I L++PL+S+ MDTVTE+ +A A
Sbjct: 2 EDKFVKEGLTFDDVLLIPAKSDVLPKDVDLKTRLTKKITLNIPLMSAGMDTVTEARLAIA 61
Query: 78 MALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISG 137
+A GGIGVIH N ++E+QA V VK +G I P S+SPD + + + ISG
Sbjct: 62 IAREGGIGVIHKNMSIERQAMEVDKVKRSEHGVITDPFSLSPDHTIRDAAELMARYKISG 121
Query: 138 ILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNR 197
+ +T D KL+GI+ +DI F D P+ + MT+ EN+ LEEA +L +
Sbjct: 122 VPIT----VDSKLVGIITNRDIRFEDDLDKPIREVMTK-ENLVTAPPGTTLEEAKQILKK 176
Query: 198 SRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAAL 257
+ LP++++ + + L + +D +A ++PN++ D G LL AAA + RV AL
Sbjct: 177 HKIEKLPLVDENNVLKGLITIKDIEKAVEFPNAAKDEKGRLLVAAAVGVGKDMMDRVKAL 236
Query: 258 SEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRI 317
EAG+D +V+D++ G++ + + +K+ YP ++++AGNV T + ++LI+ GAD++++
Sbjct: 237 IEAGVDAIVVDTAHGHSTRVLDAVAKIKEKYPDVQLIAGNVATAEATRDLIERGADAVKV 296
Query: 318 GMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANV 377
G+G GSIC T+ V G PQ TAIY+ A+ A G+P +ADGG++ GD+ KA+A GA+V
Sbjct: 297 GIGPGSICTTRVVAGVGVPQITAIYECAKEADKYGIPVIADGGIKYSGDIVKAIAAGASV 356
Query: 378 AMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGV 437
M+GS+ AGT E+PGE G K YRGMGS+ AM +G S RY E V +GV
Sbjct: 357 VMIGSLFAGTEESPGEIEIYQGRSYKVYRGMGSLGAMKEG--SSDRYFQEEAVKLVPEGV 414
Query: 438 AGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAV 497
G V +G + + + + GL+ G + + +R K F R T E
Sbjct: 415 EGRVPYRGPLRETVYQLIGGLRAGMGYCGVKNIEELRTK-----TKFVRITQAGLIESHP 469
Query: 498 HSL 500
H +
Sbjct: 470 HDI 472
>ref|XP_001252299.1| PREDICTED: inosine monophosphate dehydrogenase 1 [Bos taurus]
Length = 660
Score = 886 bits (2290), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 359/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 156 TGYVPEDGLTAQQLFANADGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSP 215
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 216 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 275
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 276 VLEAKIRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRNELVVAP 335
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA
Sbjct: 336 AGVTLKEANEILQRSKKGKLPIVNDRDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAA 395
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 396 VGTREDDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 455
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 456 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQT 515
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 516 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 575
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 576 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELK 635
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 636 FEKRTMSAQIEGGVHGLHSYEKRLY 660
>ref|ZP_02914844.1| inosine-5'-monophosphate dehydrogenase [Geobacillus sp. WCH70]
gb|EDT34011.1| inosine-5'-monophosphate dehydrogenase [Geobacillus sp. WCH70]
Length = 488
Score = 883 bits (2282), Expect = 0.0, Method: Composition-based stats.
Identities = 176/485 (36%), Positives = 279/485 (57%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F+++GL+F+D +++P D V+V+ + ++ + L++P++S+ MDTVTE+ MA
Sbjct: 2 WESKFAKEGLTFDDVLLIPAKSDVLPRDVDVTTKLSETLQLNIPIISAGMDTVTEAEMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK G I P ++P+ V ++ S+ IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSERGVITDPFFLTPEHQVYDAEHLMSKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ + + + KL+GI+ +D+ F++D S ++ MT+ EN+ LEEA +L
Sbjct: 122 GVPIVNN-EEEQKLVGIITNRDLRFIQDYSIKIADVMTK-ENLITAPVGTTLEEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP++++ + L + +D + ++PNS+ D G LL AA RV
Sbjct: 180 KYKVEKLPLVDENGVLKGLITIKDIEKVIEFPNSAKDAKGRLLVGAAVGVTADTMIRVKK 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L EA +DV+V+D++ G++ + +R +++ YP L ++AGNV T + ++LI+AGA+ ++
Sbjct: 240 LVEANVDVIVVDTAHGHSKGVLETVRKIREQYPDLNIIAGNVATAEATRDLIEAGANIIK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TAIY A A GVP +ADGG++ GD+ KALA GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQITAIYDCATEARKYGVPIIADGGIKYSGDIVKALAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
MLGS++AG SE+PGE G R K YRGMGS+ AM +G S RY E+ V +G
Sbjct: 360 AVMLGSLLAGVSESPGETEIYQGRRFKVYRGMGSVAAMEKG--SKDRYFQEDNKKFVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + + +REK F R T E
Sbjct: 418 IEGRVPYKGPLADTIYQLVGGLRAGMGYCGTRNLEELREKTQ-----FIRMTSAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHDVQ 477
>ref|NP_000874.2| inosine monophosphate dehydrogenase 1 isoform a [Homo sapiens]
gb|EAL24310.1| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
Length = 599
Score = 880 bits (2276), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 358/505 (70%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 95 TGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 154
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 155 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 214
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 215 VLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAP 274
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 275 AGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAA 334
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 335 VGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 394
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 395 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQT 454
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 455 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 514
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 515 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELK 574
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 575 FEKRTMSAQIEGGVHGLHSYEKRLY 599
>ref|NP_001096075.1| inosine monophosphate dehydrogenase 1 isoform c [Homo sapiens]
Length = 589
Score = 880 bits (2275), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 358/505 (70%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 85 TGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 144
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 145 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 204
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 205 VLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAP 264
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 265 AGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAA 324
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 325 VGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 384
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 385 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQT 444
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 445 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 504
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 505 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELK 564
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 565 FEKRTMSAQIEGGVHGLHSYEKRLY 589
>ref|YP_145862.1| inositol-5-monophosphate dehydrogenase [Geobacillus kaustophilus
HTA426]
dbj|BAD74294.1| inositol-monophosphate dehydrogenase [Geobacillus kaustophilus
HTA426]
Length = 488
Score = 879 bits (2274), Expect = 0.0, Method: Composition-based stats.
Identities = 177/485 (36%), Positives = 278/485 (57%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F+++GL+F+D +++P D V+V+ + + + L++P++S+ MDTVTE+ MA
Sbjct: 2 WEAKFAKEGLTFDDVLLIPAKSDVLPRDVDVTTKLSDTLQLNIPILSAGMDTVTEAEMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK G I P ++PD V ++ S+ IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSERGVITDPFFLTPDHQVYDAEHLMSKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ + + KL+GI+ +D+ F++D S +S+ MT+ EN+ LEEA +L
Sbjct: 122 GVPIVNNP-EEQKLVGIITNRDLRFIQDYSIKISEVMTK-ENLITAPVGTTLEEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
R + LP++++ + L + +D + ++PNS+ D G L+ AA RV
Sbjct: 180 RHKVEKLPLVDENGVLKGLITIKDIEKVIEFPNSAKDAKGRLIVGAAVGVTADTMIRVKK 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L EAG+DV+V+D++ G++ + + +++ YP L ++AGNV T + ++LI+AGA+ ++
Sbjct: 240 LVEAGVDVIVVDTAHGHSKGVLETVANIRRQYPDLNIIAGNVATAEGTRDLIEAGANIIK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TAIY A A GVP +ADGG++ GD+ KA+A GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGVPIIADGGIKYSGDIVKAIAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
MLGS++AG SE+PGE G R K YRGMGS+ AM +G S RY E+ V +G
Sbjct: 360 AVMLGSLLAGVSESPGETEIYQGRRFKVYRGMGSVAAMERG--SKDRYFQEDAKKFVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + + +REK F R T E
Sbjct: 418 IEGRVPYKGPLADTIYQLVGGLRAGMGYCGTRNLEELREKTQ-----FIRMTSAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHDVQ 477
>ref|NP_899066.1| inosine monophosphate dehydrogenase 1 isoform b [Homo sapiens]
gb|EAL24311.1| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
gb|AAH33622.2| IMP (inosine monophosphate) dehydrogenase 1 [Homo sapiens]
Length = 563
Score = 879 bits (2274), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 358/505 (70%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 59 TGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 118
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 119 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 178
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 179 VLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAP 238
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 239 AGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAA 298
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 299 VGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 358
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 359 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQT 418
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 419 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 478
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 479 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELK 538
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 539 FEKRTMSAQIEGGVHGLHSYEKRLY 563
>gb|EAW83652.1| IMP (inosine monophosphate) dehydrogenase 1, isoform CRA_d [Homo
sapiens]
Length = 522
Score = 878 bits (2269), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 358/505 (70%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 18 TGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 77
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 78 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 137
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 138 VLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAP 197
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 198 AGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAA 257
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 258 VGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 317
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 318 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQT 377
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 378 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 437
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 438 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELK 497
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 498 FEKRTMSAQIEGGVHGLHSYEKRLY 522
>sp|P20839|IMDH1_HUMAN Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1)
(IMPDH-I) (IMPD 1)
Length = 514
Score = 877 bits (2268), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 358/505 (70%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 10 TGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 70 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 130 VLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 250 VGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 310 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQT 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 370 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 430 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 490 FEKRTMSAQIEGGVHGLHSYEKRLY 514
>ref|NP_001071309.1| inosine monophosphate dehydrogenase 1 [Bos taurus]
gb|AAI26585.1| IMP (inosine monophosphate) dehydrogenase 1 [Bos taurus]
Length = 571
Score = 877 bits (2268), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 359/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 67 TGYVPEDGLTAQQLFANADGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSP 126
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 127 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 186
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 187 VLEAKIRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRNELVVAP 246
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA
Sbjct: 247 AGVTLKEANEILQRSKKGKLPIVNDRDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAA 306
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 307 VGTREDDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 366
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 367 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQT 426
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 427 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 486
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 487 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELK 546
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 547 FEKRTMSAQIEGGVHGLHSYEKRLY 571
>ref|ZP_01667581.1| inosine-5'-monophosphate dehydrogenase [Thermosinus carboxydivorans
Nor1]
gb|EAX46553.1| inosine-5'-monophosphate dehydrogenase [Thermosinus carboxydivorans
Nor1]
Length = 484
Score = 877 bits (2268), Expect = 0.0, Method: Composition-based stats.
Identities = 178/484 (36%), Positives = 283/484 (58%), Gaps = 12/484 (2%)
Query: 18 EELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARA 77
++ F +GL+F+D +++P D +V+VS T+NI L++P++SS MDTVTE+ MA A
Sbjct: 3 DDKFGPEGLTFDDVLLIPAKSDVLPREVDVSTNLTRNIKLNIPIISSGMDTVTEARMAIA 62
Query: 78 MALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISG 137
MA GG+GVIH N ++E+QA + VK +G I+ P +SP+ + ++ + ISG
Sbjct: 63 MAREGGLGVIHKNMSIERQANEIDKVKRSEHGIIVDPIFLSPENTLQDAHDLMEKYRISG 122
Query: 138 ILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNR 197
+ VT+ GKL+GI+ +D+ F D + + MT E++ LE+A ++L +
Sbjct: 123 VPVTDK----GKLVGILTNRDLRFETDLRRKIRECMTH-EHLITAPVGTSLEQAKEILRQ 177
Query: 198 SRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAAL 257
R LP++++ + L + +D +A+ YPNS+ D G LL AAA RV A+
Sbjct: 178 HRIEKLPLVDEHGNLKGLITIKDIEKAQKYPNSAKDNKGRLLVAAAVGVGADMMDRVDAI 237
Query: 258 SEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRI 317
A +DV+V+D++ G++ + ++ +K+ YP+++++AGNV T + ++LI+AGAD++++
Sbjct: 238 VAAKVDVIVIDTAHGHSRGVLEAVKKIKQAYPNIDLIAGNVATAEATRDLIEAGADAVKV 297
Query: 318 GMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANV 377
G+G GSIC T+ + G PQ TAIY AR A VP +ADGG++ GD+ KA+A GA+V
Sbjct: 298 GIGPGSICTTRVIAGIGVPQITAIYDCARAAREYKVPIIADGGIKYSGDITKAIAAGAHV 357
Query: 378 AMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGV 437
M+G+++AGT E+PGE G K YRGMGS+ AM +G S RY EN V +G+
Sbjct: 358 VMIGNLLAGTEESPGEMIIYQGRSYKVYRGMGSLGAMAEG--SKDRYFQENMDKLVPEGI 415
Query: 438 AGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAV 497
G V KGSV + + GL+ G + + + + F R T E
Sbjct: 416 EGRVPYKGSVADTVFQLVGGLKAGMGYCGVRNIEEL-----INKTRFIRITGAGLKESHP 470
Query: 498 HSLH 501
H +H
Sbjct: 471 HDIH 474
>gb|EDL13789.1| inosine 5'-phosphate dehydrogenase 1, isoform CRA_b [Mus musculus]
Length = 607
Score = 877 bits (2267), Expect = 0.0, Method: Composition-based stats.
Identities = 268/505 (53%), Positives = 359/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 103 TGYVPEDGLTAQQLFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 162
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 163 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 222
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K + G SGI +T G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 223 VLEAKIQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRVELVVAP 282
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA
Sbjct: 283 AGVTLKEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAA 342
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 343 VGTREDDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 402
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 403 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQT 462
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 463 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 522
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 523 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELK 582
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 583 FEKRTMSAQIEGGVHGLHSYEKRLY 607
>ref|YP_360021.1| inosine-5'-monophosphate dehydrogenase [Carboxydothermus
hydrogenoformans Z-2901]
gb|ABB13667.1| inosine-5'-monophosphate dehydrogenase [Carboxydothermus
hydrogenoformans Z-2901]
Length = 483
Score = 875 bits (2262), Expect = 0.0, Method: Composition-based stats.
Identities = 181/483 (37%), Positives = 271/483 (56%), Gaps = 12/483 (2%)
Query: 18 EELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARA 77
E ++GL+F+D +++P + V+ + +FTK I L++P+VS+ MDTVTE+ MA A
Sbjct: 2 ESKIVKEGLTFDDVLLIPAKSEVLPRDVDTTTRFTKKIKLNIPIVSAGMDTVTEARMAIA 61
Query: 78 MALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISG 137
MA GGIGVIH N ++E+QA V VK +G I P S+SP+ + I ISG
Sbjct: 62 MAREGGIGVIHKNMSIEEQAMEVDKVKRSEHGIIADPISLSPEHLIRDALEIMERYHISG 121
Query: 138 ILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNR 197
+ +T +GKL+GI+ +D+ F D S ++ MT+ +N+ L+EA +L +
Sbjct: 122 VPIT----VEGKLVGIITNRDLRFESDYSKKIADVMTK-DNLITAPVGTSLKEAEKILQK 176
Query: 198 SRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAAL 257
+ LP++++ + L + +D + R YPN++ D G L AAA RV AL
Sbjct: 177 HKIEKLPLVDENFHLKGLITIKDIEKTRKYPNAAKDEKGRLRVAAAVGVSRDMMDRVKAL 236
Query: 258 SEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRI 317
EA +D +V+D++ G++ + + +K YP +E+VAGNV T + ++LI AGAD++++
Sbjct: 237 VEAKVDAIVVDTAHGHSRGVLEAVYKIKSKYPEVELVAGNVATAEATEDLIKAGADAVKV 296
Query: 318 GMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANV 377
G+G GSIC T+ V G PQ TAI A A VP +ADGG++ GD+ KALA GA+
Sbjct: 297 GIGPGSICTTRVVAGIGVPQITAILDCAEVAMKYDVPIIADGGIKYSGDITKALAAGADT 356
Query: 378 AMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGV 437
MLGS++AGT E+PGE G K YRGMGS+ AM +G S RY ENE V +GV
Sbjct: 357 VMLGSLLAGTEESPGEIEIWQGRSYKVYRGMGSLGAMKEG--SKDRYFQENEQKLVPEGV 414
Query: 438 AGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAV 497
G V KG V + + + GL+ G + ++ K F + T E
Sbjct: 415 EGRVPFKGPVSETIFQLIGGLRAGMGYCGVRNIYELKTK-----TKFIKITQAGLRESHP 469
Query: 498 HSL 500
H +
Sbjct: 470 HDV 472
>emb|CAA39204.1| IMP dehydrogenase [Bacillus subtilis]
Length = 513
Score = 874 bits (2260), Expect = 0.0, Method: Composition-based stats.
Identities = 179/485 (36%), Positives = 277/485 (57%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E FS++GL+F+D +++P + V++S + TK + L++P++S+ MDTVTES+MA
Sbjct: 2 WESKFSKEGLTFDDVLLVPAKSEVLPHDVDLSVELTKTLKLNIPVISAGMDTVTESAMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK G I P ++PD V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSERGVITNPFFLTPDHQVFDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ + + D KL+GI+ +D+ F+ D S +S MT+ E + L+EA +L
Sbjct: 122 GVPIVNN-EEDQKLVGIITNRDLRFISDYSMKISDVMTK-EELVTASVGTTLDEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP+++D++++ L + +D + ++PNSS D +G L+ AA RV
Sbjct: 180 KHKIEKLPLVDDQNKLKGLITIKDIEKVIEFPNSSKDIHGRLIVGAAVGVTGDTMTRVKK 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L EA +DV+V+D++ G++ ++ + +++TYP L ++AGNV T + + LI+AGAD ++
Sbjct: 240 LVEANVDVIVIDTAHGHSQGVLNTVTKIRETYPELNIIAGNVATAEATRALIEAGADVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TAIY A A G +ADGG++ GD+ KALA G +
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKTIIADGGIKFSGDITKALAAGGH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
MLGS++AGTSE+PGE G R K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 AVMLGSLLAGTSESPGETEIYQGRRFKVYRGMGSVAAMEKG--SKDRYFQEENKKFVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G KG V + + + GL+ G A+RE+ F R T E
Sbjct: 418 IEGRTPYKGPVEETVYQLVGGLRSGMGYCGSKDLRALREEAQ-----FIRMTGAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHDVQ 477
>ref|NP_240886.1| inositol-5-monophosphate dehydrogenase [Bacillus halodurans C-125]
sp|Q9KGN8|IMDH_BACHD Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH)
(IMPD)
dbj|BAB03739.1| inositol-monophosphate dehydrogenase [Bacillus halodurans C-125]
Length = 485
Score = 874 bits (2259), Expect = 0.0, Method: Composition-based stats.
Identities = 172/485 (35%), Positives = 278/485 (57%), Gaps = 11/485 (2%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F ++GL+F+D +++P + V+V + T+ + L++P++S+ MDTVTE+ MA
Sbjct: 2 WENKFQKEGLTFDDVLLVPAKSEVLPRDVSVKTKLTETLQLNIPIISAGMDTVTEAKMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
A+A GG+G+IH N +VE+QA V VK +G I P ++PD V ++ + IS
Sbjct: 62 AIAREGGLGIIHKNMSVEEQAEQVDRVKRSESGVITNPFFLTPDRQVFDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ + + D KL+GI+ +D+ F++D S + MT+ EN+ L+EA ++L
Sbjct: 122 GVPIVD---EDQKLVGILTNRDLRFIEDYSTLIDDVMTK-ENLVTAPVGTTLKEAEEILQ 177
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP++++ + L + +D + ++PNS+ D G L+ AA RVAA
Sbjct: 178 KHKIEKLPLVDESGTLKGLITIKDIEKVIEFPNSAKDSQGRLIVGAAVGVSADTDVRVAA 237
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L EAG+DV+V+D++ G++ + ++ +++ YP L ++AGNV T + ++LI+AGA+ ++
Sbjct: 238 LVEAGVDVIVIDTAHGHSKGVLEKVKAIREQYPDLTIIAGNVATAEATRDLIEAGANVVK 297
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A GVP +ADGG++ GD+ KALA G +
Sbjct: 298 VGIGPGSICTTRIVAGIGVPQITAVYDCANEARKHGVPIIADGGIKYSGDIVKALAAGGH 357
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
MLGS++AG SE+PGE G + K YRGMGS+ AM +G S RY EN V +G
Sbjct: 358 AVMLGSLLAGVSESPGEREIFQGRQFKVYRGMGSLGAMEKG--SKDRYFQENNQKLVPEG 415
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G + KG + + + G++ G + D +RE F R T E
Sbjct: 416 IEGRIPYKGPLHDTIHQLVGGIRAGMGYCGTKTIDELRENTQ-----FIRITGAGLRESH 470
Query: 497 VHSLH 501
H +
Sbjct: 471 PHDVQ 475
>ref|YP_001124141.1| inositol-5-monophosphate dehydrogenase [Geobacillus
thermodenitrificans NG80-2]
gb|ABO65396.1| Inosine-monophosphate dehydrogenase [Geobacillus
thermodenitrificans NG80-2]
Length = 488
Score = 873 bits (2257), Expect = 0.0, Method: Composition-based stats.
Identities = 175/485 (36%), Positives = 276/485 (56%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F+++GL+F+D +++P D V+V+ + + + L++P++S+ MDTVTE+ MA
Sbjct: 2 WEAKFAKEGLTFDDVLLIPAKSDVLPRDVDVTTRLSDTLQLNIPIISAGMDTVTEAEMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK G I P ++PD V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSERGVITDPFFLTPDHQVYDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ + + KL+GI+ +D+ F++D S +S+ MT+ EN+ LEEA +L
Sbjct: 122 GVPIVNNA-EEQKLVGIITNRDLRFIQDYSIKISEVMTK-ENLITAPVGTTLEEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP++++ + L + +D + ++PNS+ D G L+ AA RV
Sbjct: 180 QHKVEKLPLVDENGILKGLITIKDIEKVIEFPNSAKDAKGRLVVGAAVGVTADTMIRVKK 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L EAG+DV+V+D++ G++ + + +++ YP L ++AGNV T + ++LI+AGA+ ++
Sbjct: 240 LVEAGVDVIVVDTAHGHSKGVLETVANIRRQYPDLNIIAGNVATAEATRDLIEAGANIIK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TAIY A A GVP +ADGG++ GD+ KA+A GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGVPIIADGGIKYSGDIVKAMAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
MLGS++AG SE+PGE G R K YRGMGS+ +M +G S RY E V +G
Sbjct: 360 AVMLGSLLAGVSESPGETEIYQGRRFKVYRGMGSVASMERG--SKDRYFQEEAKKFVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + D +REK F R T E
Sbjct: 418 IEGRVPYKGPLADTIYQLVGGLRAGMGYCGTRNLDELREKTQ-----FIRMTGAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHDVQ 477
>pdb|1JCN|A Chain A, Binary Complex Of Human Type-I Inosine Monophosphate
Dehydrogenase With 6-Cl-Imp
pdb|1JCN|B Chain B, Binary Complex Of Human Type-I Inosine Monophosphate
Dehydrogenase With 6-Cl-Imp
Length = 514
Score = 873 bits (2256), Expect = 0.0, Method: Composition-based stats.
Identities = 268/505 (53%), Positives = 357/505 (70%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ D L++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 10 TGYVPEDGLTAQQLFASADDLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 70 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKNFEQGFITDPVVLSPSHTVGD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 130 VLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 250 VGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 310 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQT 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 370 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 430 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 490 FEKRTMSAQIEGGVHGLHSYEKRLY 514
>ref|YP_076743.1| inosine-5'-monophosphate dehydrogenase [Symbiobacterium
thermophilum IAM 14863]
dbj|BAD41899.1| inosine-5'-monophosphate dehydrogenase [Symbiobacterium
thermophilum IAM 14863]
Length = 486
Score = 871 bits (2252), Expect = 0.0, Method: Composition-based stats.
Identities = 185/483 (38%), Positives = 282/483 (58%), Gaps = 10/483 (2%)
Query: 18 EELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARA 77
+ F + L+F+D +++P + V+VS + T+ I L++PLVS+ MDTVTE+ MA A
Sbjct: 2 DAKFGPEALTFDDVLLVPAHSEVLPRDVDVSTRLTRKIRLNIPLVSAAMDTVTEARMAIA 61
Query: 78 MALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISG 137
MA GGIG+IH + ++E+QA V VK +G I+ P V PD + T + + ISG
Sbjct: 62 MAREGGIGIIHKSMSIERQAEEVDKVKRSEHGIIVDPVFVHPDDMIETALQLMARYRISG 121
Query: 138 ILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNR 197
V E G + KL+GI+ +D+ F + + PV MT REN+ LE+A ++L
Sbjct: 122 TPVVERGTH--KLVGILTNRDLRFEDNWNQPVGNVMT-RENLITAPVGTTLEQAREILRH 178
Query: 198 SRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAAL 257
++ LP++++ + L + +D +A+ YPNS+ D +G LLC AA + R AL
Sbjct: 179 AKVEKLPLVDEHGVLKGLITIKDIEKAKKYPNSAKDEHGRLLCGAAVGVSDDLMERAGAL 238
Query: 258 SEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRI 317
+AG+DVLVLDS+ G++ + +R VK+ +P ++V+AGNV T + ++LI+AGAD++++
Sbjct: 239 VDAGVDVLVLDSAHGHSRGIMEALRKVKRNFPQVQVIAGNVATYEGTRDLIEAGADAVKV 298
Query: 318 GMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANV 377
G+G GSIC T+ V G PQ TAIY+ AR A VP +ADGG++ GD+ KA+A GA+
Sbjct: 299 GIGPGSICTTRVVAGIGVPQITAIYESARAADEYDVPIIADGGIKYSGDITKAIAAGASA 358
Query: 378 AMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGV 437
M+GS+ AGT E+PGE G K YRGMGS+ AM QG SG RY E V +G+
Sbjct: 359 VMIGSLFAGTDESPGEMEIYQGRSFKVYRGMGSLGAMKQG--SGDRYFQEGAPKLVPEGI 416
Query: 438 AGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAV 497
G V +G + +++ + GL+ G + + +R+ F R T E
Sbjct: 417 EGRVPYRGPLAEMVFQLVGGLRAGMGYCGTRTIEELRK-----NGKFCRITAAGLRESHP 471
Query: 498 HSL 500
H +
Sbjct: 472 HDV 474
>emb|CAK04261.1| novel protein similar to vertebrate IMP (inosine monophosphate)
dehydrogenase 1 (IMPDH1) [Danio rerio]
Length = 534
Score = 871 bits (2252), Expect = 0.0, Method: Composition-based stats.
Identities = 278/505 (55%), Positives = 362/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF S +V+++ T+ I L PL+SSP
Sbjct: 30 TGYVPEDGLTAQQLFAIGDGLTYNDFLILPGFIDFISDEVDLTSALTRKITLKTPLISSP 89
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTESSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 90 MDTVTESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSPRHTVGD 149
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI VTE GK KL+GIV ++DIDF KD P+ + MT+RE++ V
Sbjct: 150 VFEAKVRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLSEKDYDRPLEESMTKREDLVVAP 209
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA D+L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 210 AGVTLKEANDILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAA 269
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L +AG+DV+VLDSSQGN+++Q+S I ++K+ YP L+VV GNVVT Q
Sbjct: 270 IGTREDDKYRLDLLMQAGVDVIVLDSSQGNSVFQISMINYIKQKYPELQVVGGNVVTAAQ 329
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++
Sbjct: 330 AKNLIDAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQT 389
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 390 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNNSSQKR 449
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 450 YFSEGDKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELK 509
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 510 FEKRTMSAQVEGGVHGLHSYEKRLY 534
>gb|EAW83649.1| IMP (inosine monophosphate) dehydrogenase 1, isoform CRA_a [Homo
sapiens]
Length = 561
Score = 870 bits (2250), Expect = 0.0, Method: Composition-based stats.
Identities = 268/505 (53%), Positives = 357/505 (70%), Gaps = 5/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 59 TGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 118
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR K + GFI P +SP V
Sbjct: 119 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVR--KKFEQGFITDPVVLSPSHTVGD 176
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 177 VLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAP 236
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 237 AGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAA 296
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG+DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 297 VGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 356
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 357 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQT 416
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 417 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 476
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 477 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELK 536
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 537 FEKRTMSAQIEGGVHGLHSYEKRLY 561
>gb|EDM15208.1| IMP (inosine monophosphate) dehydrogenase 1 (predicted), isoform
CRA_b [Rattus norvegicus]
Length = 514
Score = 870 bits (2250), Expect = 0.0, Method: Composition-based stats.
Identities = 268/505 (53%), Positives = 359/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 10 TGYVPEDGLTAQQLFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 70 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K + G SGI +T G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 130 VLEAKIQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 250 VGTREDDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 310 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQT 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 370 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 430 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 490 FEKRTMSAQIEGGVHGLHSYEKRLY 514
>ref|YP_001695789.1| Inosine-5'-monophosphate dehydrogenase [Lysinibacillus sphaericus
C3-41]
gb|ACA37659.1| Inosine-5'-monophosphate dehydrogenase [Lysinibacillus sphaericus
C3-41]
Length = 487
Score = 870 bits (2249), Expect = 0.0, Method: Composition-based stats.
Identities = 173/485 (35%), Positives = 275/485 (56%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F+++GL+F+D +++P + V++S Q T I L++P++S+ MDTVTES MA
Sbjct: 2 WETKFAKEGLTFDDVLLVPAHSEVLPKDVDLSVQLTPKIKLNIPMISAGMDTVTESKMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GGIG+IH N +++QA V VK NG I P ++P V ++ + IS
Sbjct: 62 AMARQGGIGIIHKNMGIDEQAEQVEKVKRSENGVITNPFFLTPTHQVFDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ + + + KL+GI+ +D+ F+ D S + MT+ E++ LE+A +L
Sbjct: 122 GVPIVDS-MENQKLVGIITNRDLRFISDYSLKIEDVMTK-EDLITAPVGTTLEDAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP+++++ + L + +D + ++PN++ D +G LL AA + R+
Sbjct: 180 QYKIEKLPIVDEEGRLTGLITIKDIEKVIEFPNAAKDTHGRLLVGAAVGVSKDTMVRIEK 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L EA +D++V+D++ G++ + IR +++TYP LE++AGNV T + A+ L +AGAD ++
Sbjct: 240 LVEAQVDIVVIDTAHGHSEGVLQTIRSIRETYPELEIIAGNVATAEGARALFEAGADVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A G +ADGG++ GD+ KALA G N
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQITAVYDCATVARELGKTIIADGGIKYSGDIVKALAAGGN 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
V MLGS++AGTSE+PGE G R K YRGMGSI AM +G S RY E+ V +G
Sbjct: 360 VVMLGSLLAGTSESPGETEIFQGRRFKVYRGMGSIGAMEKG--SKDRYFQEDAKKLVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G + KG + + + G++ G + +RE F + T E
Sbjct: 418 IEGRLPYKGPLADTIYQLIGGIRAGMGYCGAPHLEYLRENAQ-----FVKMTGAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHDVQ 477
>ref|NP_035959.2| inosine 5'-phosphate dehydrogenase 1 [Mus musculus]
gb|AAH53416.1| Inosine 5'-phosphate dehydrogenase 1 [Mus musculus]
dbj|BAE42272.1| unnamed protein product [Mus musculus]
gb|EDL13790.1| inosine 5'-phosphate dehydrogenase 1, isoform CRA_c [Mus musculus]
Length = 514
Score = 869 bits (2248), Expect = 0.0, Method: Composition-based stats.
Identities = 268/505 (53%), Positives = 359/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 10 TGYVPEDGLTAQQLFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 70 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K + G SGI +T G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 130 VLEAKIQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRVELVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 250 VGTREDDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 310 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQT 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 370 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 430 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 490 FEKRTMSAQIEGGVHGLHSYEKRLY 514
>ref|XP_001372080.1| PREDICTED: similar to Inosine monophosphate dehydrogenase 1
[Monodelphis domestica]
Length = 575
Score = 869 bits (2247), Expect = 0.0, Method: Composition-based stats.
Identities = 269/505 (53%), Positives = 357/505 (70%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 71 TGYVPEDGLTAQQLFAIADGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSP 130
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 131 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 190
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R ++ V
Sbjct: 191 VLEAKMRHGFSGIPITETGAMGSKLVGIVTSRDIDFLAEKDHATYLSEVMTGRNDLVVAP 250
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D + LLC AA
Sbjct: 251 AGVTLKEANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDAHKQLLCGAA 310
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG DV+VLDSSQGN++YQ++ + ++K YP L+V+ GNVVT Q
Sbjct: 311 VGTREDDKYRLDLLTQAGADVIVLDSSQGNSVYQIAMVHYIKHKYPQLQVIGGNVVTAAQ 370
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 371 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQT 430
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 431 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKR 490
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 491 YFSEGDKVKVAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELK 550
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 551 FEKRTMSAQIEGGVHGLHSYEKRLY 575
>ref|NP_387890.1| inositol-5-monophosphate dehydrogenase [Bacillus subtilis subsp.
subtilis str. 168]
sp|P21879|IMDH_BACSU Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH)
(IMPD) (Superoxide-inducible protein 12) (SOI12)
dbj|BAA05245.1| IMP dehydrogenase [Bacillus subtilis]
emb|CAB11785.1| inosine-monophosphate dehydrogenase [Bacillus subtilis subsp.
subtilis str. 168]
Length = 488
Score = 869 bits (2247), Expect = 0.0, Method: Composition-based stats.
Identities = 179/485 (36%), Positives = 277/485 (57%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E FS++GL+F+D +++P + V++S + TK + L++P++S+ MDTVTES+MA
Sbjct: 2 WESKFSKEGLTFDDVLLVPAKSEVLPRDVDLSVELTKTLKLNIPVISAGMDTVTESAMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK G I P ++PD V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSERGVITNPFFLTPDHQVFDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ + + D KL+GI+ +D+ F+ D S +S MT+ E + L+EA +L
Sbjct: 122 GVPIVNN-EEDQKLVGIITNRDLRFISDYSMKISDVMTK-EELVTASVGTTLDEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP+++D++++ L + +D + ++PNSS D +G L+ AA RV
Sbjct: 180 KHKIEKLPLVDDQNKLKGLITIKDIEKVIEFPNSSKDIHGRLIVGAAVGVTGDTMTRVKK 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L EA +DV+V+D++ G++ ++ + +++TYP L ++AGNV T + + LI+AGAD ++
Sbjct: 240 LVEANVDVIVIDTAHGHSQGVLNTVTKIRETYPELNIIAGNVATAEATRALIEAGADVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TAIY A A G +ADGG++ GD+ KALA G +
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKTIIADGGIKFSGDITKALAAGGH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
MLGS++AGTSE+PGE G R K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 AVMLGSLLAGTSESPGETEIYQGRRFKVYRGMGSVAAMEKG--SKDRYFQEENKKFVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G KG V + + + GL+ G A+RE+ F R T E
Sbjct: 418 IEGRTPYKGPVEETVYQLVGGLRSGMGYCGSKDLRALREEAQ-----FIRMTGAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHDVQ 477
>ref|YP_545250.1| inosine-5'-monophosphate dehydrogenase [Methylobacillus flagellatus
KT]
gb|ABE49409.1| inosine-5'-monophosphate dehydrogenase [Methylobacillus flagellatus
KT]
Length = 486
Score = 868 bits (2244), Expect = 0.0, Method: Composition-based stats.
Identities = 177/484 (36%), Positives = 279/484 (57%), Gaps = 14/484 (2%)
Query: 21 FSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARAMAL 80
Q L+F+D +++P + +V+++ + T++I L++PL+S+ MDTVTE+ +A A+A
Sbjct: 3 LLQQALTFDDVLLVPAHSNVLPREVSLATKLTRSITLNIPLISAAMDTVTEAPLAIALAQ 62
Query: 81 MGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISGILV 140
GG+G++H N +++ QA V VK + +G + P ++ P++ V + + + ISG+ V
Sbjct: 63 EGGMGIVHKNMSIKDQAAHVSRVKRFESGVVHDPVTIQPNLTVRDVLALTRQHKISGLPV 122
Query: 141 TEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNRSRH 200
+G K++GIV +D+ F + +S MT RE + R LEEA +L++ R
Sbjct: 123 VDGK----KVVGIVTNRDLRFETNLDQAISNIMTPRERLVTVREGASLEEATALLHKHRL 178
Query: 201 GYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAALSEA 260
+ V+ND E+ L + +D ++ D+PN+ D G L AA + + RVAAL+EA
Sbjct: 179 ERVLVVNDAFELKGLITVKDIQKSSDHPNACKDEKGRLRVGAAVGVGDGTEERVAALAEA 238
Query: 261 GIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRIGMG 320
G+DV+V+D++ G++ + + WVKK +PH++V+ GN+ T + AK L+DAGAD +++G+G
Sbjct: 239 GVDVIVVDTAHGHSQGVLDRVNWVKKNFPHIQVIGGNIATANAAKALVDAGADGVKVGIG 298
Query: 321 SGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANVAML 380
GSIC T+ V G PQ +A+ V GVP +ADGG+R GD+ KA+A GA ML
Sbjct: 299 PGSICTTRIVAGVGVPQISAVSNVEEALRGTGVPFIADGGIRFSGDIAKAIAAGAYSVML 358
Query: 381 GSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENE---TLQVAQGV 437
G M AGT E PGE G K YRGMGSI AM +G S RY +N V +G+
Sbjct: 359 GGMFAGTEEAPGEIELFQGRSYKSYRGMGSIGAMEKG--SSDRYFQDNNGNVDKLVPEGI 416
Query: 438 AGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAV 497
G V KGSVL ++ + GL+ S +G + + +R + F + T E V
Sbjct: 417 EGRVPYKGSVLAVIHQLMGGLRASMGYVGCSTIEEMRTRAE-----FVQITAAGMRESHV 471
Query: 498 HSLH 501
H +
Sbjct: 472 HDVQ 475
>ref|ZP_01725067.1| inositol-5-monophosphate dehydrogenase [Bacillus sp. B14905]
gb|EAZ84377.1| inositol-5-monophosphate dehydrogenase [Bacillus sp. B14905]
Length = 487
Score = 868 bits (2244), Expect = 0.0, Method: Composition-based stats.
Identities = 172/485 (35%), Positives = 275/485 (56%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F+++GL+F+D +++P + V++S Q T I L++P++S+ MDTVTES MA
Sbjct: 2 WETKFAKEGLTFDDVLLVPAHSEVLPKDVDLSVQLTPKIKLNIPMISAGMDTVTESKMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GGIG+IH N +++QA V VK NG I P ++P V ++ + IS
Sbjct: 62 AMARQGGIGIIHKNMGIDEQAEQVEKVKRSENGVITNPFFLTPTHQVFDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ + + + KL+GI+ +D+ F+ D S + MT+ E++ LE+A +L
Sbjct: 122 GVPIVDS-MENQKLVGIITNRDLRFISDYSLKIEDVMTK-EDLITAPVGTTLEDAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP+++++ + L + +D + ++PN++ D +G LL AA + R+
Sbjct: 180 QYKIEKLPIVDEEGRLTGLITIKDIEKVIEFPNAAKDTHGRLLVGAAVGVSKDTMVRIEK 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L EA +D++V+D++ G++ + IR +++TYP LE++AGNV T + ++ L +AGAD ++
Sbjct: 240 LVEAQVDIVVIDTAHGHSEGVLQTIRSIRETYPELEIIAGNVATAEGSRALFEAGADVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A G +ADGG++ GD+ KALA G N
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQITAVYDCATVARELGKTIIADGGIKYSGDIVKALAAGGN 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
V MLGS++AGTSE+PGE G R K YRGMGSI AM +G S RY E+ V +G
Sbjct: 360 VVMLGSLLAGTSESPGETEIFQGRRFKVYRGMGSIGAMEKG--SKDRYFQEDAKKLVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G + KG + + + G++ G + +RE F + T E
Sbjct: 418 IEGRLPYKGPLADTIYQLIGGIRAGMGYCGAPHLEYLRENAQ-----FVKMTGAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHDVQ 477
>ref|YP_001373379.1| inosine-5'-monophosphate dehydrogenase [Bacillus cereus subsp.
cytotoxis NVH 391-98]
gb|ABS20384.1| inosine-5'-monophosphate dehydrogenase [Bacillus cereus subsp.
cytotoxis NVH 391-98]
Length = 487
Score = 868 bits (2243), Expect = 0.0, Method: Composition-based stats.
Identities = 172/485 (35%), Positives = 272/485 (56%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F ++GL+F+D +++P D +VNV ++++ L++PL+S+ MDTVTE+ MA
Sbjct: 2 WESKFVKEGLTFDDVLLIPAKSDVLPREVNVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK +G I P ++P+ V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ + + KL+GI+ +D+ F++D S +S MT+ E + L+EA +L
Sbjct: 122 GVPIVNNLD-EQKLVGIITNRDMRFIQDYSIKISDVMTK-EQLITAPVGTTLKEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP+++ + L + +D + ++PNS+ D+ G LL AA R+ A
Sbjct: 180 KYKIEKLPLVDQNGVLKGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMLRIDA 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L +A +DV+V+D++ G++ + ++ V+ YP L ++AGNV T + + LI+AGA+ ++
Sbjct: 240 LVKANVDVIVIDTAHGHSQGVLEKVKEVRTKYPELNIIAGNVATAEATRALIEAGANIIK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A G+P +ADGG++ GD+ KALA GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
V MLGSM AG +E+PGE G + K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 VVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKG--SKDRYFQEGNKKLVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + +RE F R T E
Sbjct: 418 IEGRVPYKGPLADTVHQLVGGLRAGMGYCGAHDLEFLRENAQ-----FIRMTGAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHHVQ 477
>dbj|BAA89464.1| IMPDH [Bacillus cereus]
Length = 509
Score = 866 bits (2238), Expect = 0.0, Method: Composition-based stats.
Identities = 171/485 (35%), Positives = 271/485 (55%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F ++GL+F+D +++P D +V+V ++++ L++PL+S+ MDTVTE+ MA
Sbjct: 2 WESKFVKEGLTFDDVLLVPAKSDVLPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK +G I P ++P+ V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ V + KL+GI+ +D+ F++D S +S MT+ E + L+EA +L
Sbjct: 122 GVPVVNNLD-ERKLVGIITNRDMRFIQDYSIKISDVMTK-EQLITAPVGTTLDEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP++++ + L + +D + ++PNS+ D+ G LL AA R+ A
Sbjct: 180 KYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMTRIDA 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L +A +D +VLD++ G++ + ++ V+ YP L ++AGNV T + LI+AGA+ ++
Sbjct: 240 LVKASVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAEATGALIEAGANVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A G+P +ADGG++ GD+ KALA GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
V MLGSM AG +E+PGE G + K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 VVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKG--SKDRYFQEGNKKLVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + +RE F R + E
Sbjct: 418 IEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQ-----FVRMSGAGLLESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHHVQ 477
>ref|YP_001419688.1| GuaB [Bacillus amyloliquefaciens FZB42]
gb|ABS72457.1| GuaB [Bacillus amyloliquefaciens FZB42]
Length = 488
Score = 865 bits (2237), Expect = 0.0, Method: Composition-based stats.
Identities = 181/485 (37%), Positives = 279/485 (57%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E FS++GL+F+D +++P D V++S + TK + L++P++S+ MDTVTES+MA
Sbjct: 2 WESKFSKEGLTFDDVLLVPAQSDVLPRDVDLSVELTKTLKLNIPVISAGMDTVTESAMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK G I P ++PD V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEHVDKVKRSERGVITNPFFLTPDHQVFDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ + + K D KL+GI+ +D+ F+ D S +S MT+ E + L+EA +L
Sbjct: 122 GVPIVDN-KDDQKLVGIITNRDLRFISDYSMKISDVMTK-EELVTASVGTTLDEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP+++D++++ L + +D + ++PNSS D +G L+ AA RV+
Sbjct: 180 KHKIEKLPLVDDQNKLKGLITIKDIEKVIEFPNSSKDEHGRLIVGAAVGVTGDTMTRVSK 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L EA +DV+V+D++ G++ ++ + +++TYP L ++AGNV T + K LI+AGA+ ++
Sbjct: 240 LVEANVDVIVVDTAHGHSRGVLNTVAKIRETYPELNIIAGNVATAEATKALIEAGANIVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TAIY A A G +ADGG++ GD+ KALA G +
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGATIIADGGIKFSGDITKALASGGH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
MLGS++AGTSE+PGE G R K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 AVMLGSLLAGTSESPGETEIYQGRRFKVYRGMGSVAAMEKG--SKDRYFQEENKKFVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G KG V + + + GL+ G A+RE+ F R T E
Sbjct: 418 IEGRTPYKGPVEETVYQLVGGLRSGMGYCGSKDLRALREEAQ-----FIRMTGAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHDVQ 477
>ref|NP_001080792.1| inosine 5'-phosphate dehydrogenase 1 [Xenopus laevis]
gb|AAH46868.1| Impdh1-prov protein [Xenopus laevis]
Length = 514
Score = 865 bits (2237), Expect = 0.0, Method: Composition-based stats.
Identities = 273/505 (54%), Positives = 362/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ +GL++NDF+ILPGFIDF + +V+++ T+ I L P++SSP
Sbjct: 10 TGYVPEDGLTAQQLFANSEGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPMISSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTES MA AMALMGGIG+IH+NCT E QA VR VK + GFI P +S + V
Sbjct: 70 MDTVTESDMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSLNHTVGD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G SGI VTE GK KL+GIV ++DIDF KD S +S+ MT+RE++ V
Sbjct: 130 VFEAKNRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLTEKDYSTYLSEVMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDCRKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L +AG+DV+VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT Q
Sbjct: 250 IGTREDDKYRLDLLMQAGVDVVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP VADGG++
Sbjct: 310 AKNLIDAGVDALRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVVADGGIQT 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 370 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSTSSQKR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 430 YFSEGDKVKVAQGVSGSIQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
+RT++AQ EG VH LH YE++L+
Sbjct: 490 LEKRTMSAQVEGGVHGLHSYEKRLY 514
>ref|NP_001017283.1| IMP (inosine monophosphate) dehydrogenase 1 [Xenopus tropicalis]
emb|CAJ83974.1| IMP (inosine monophosphate) dehydrogenase 1 [Xenopus tropicalis]
Length = 514
Score = 865 bits (2236), Expect = 0.0, Method: Composition-based stats.
Identities = 273/505 (54%), Positives = 361/505 (71%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA+ LF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 10 TGYVPEDGLTAQHLFANSDGLTYNDFLILPGFIDFTADEVDLTSALTRKITLKTPLISSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTES MA AMALMGGIG+IH+NCT E QA VR VK + GFI P +S + V
Sbjct: 70 MDTVTESDMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSLNHTVGD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K+ G SGI VTE GK KL+GIV ++DIDF KD S +S+ MT+R+ + V
Sbjct: 130 VFEAKNRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLTEKDYSTYLSEVMTKRDELVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDCRKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG+DV+VLDSSQGN++YQ++ I ++K+ YP L+VV GNVVT Q
Sbjct: 250 IGTREDDKYRLDLLTQAGVDVVVLDSSQGNSVYQINMIHYIKQKYPELQVVGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 310 AKNLIDAGVDALRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQT 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 370 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNTSSQKR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 430 YFSEGDKVKVAQGVSGSIQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
+RT++AQ EG VH LH YE++L+
Sbjct: 490 LEKRTMSAQVEGGVHGLHSYEKRLY 514
>ref|ZP_02079836.1| hypothetical protein CLOLEP_01281 [Clostridium leptum DSM 753]
gb|EDO61777.1| hypothetical protein CLOLEP_01281 [Clostridium leptum DSM 753]
Length = 492
Score = 864 bits (2235), Expect = 0.0, Method: Composition-based stats.
Identities = 192/489 (39%), Positives = 283/489 (57%), Gaps = 14/489 (2%)
Query: 15 TTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSM 74
T +E F ++GL+F+D +++PG + +V+VS TK I L+ PL+++ MDTVTE+ M
Sbjct: 4 TNFQEKFVKEGLTFDDVLLIPGESNVQPKEVDVSTWLTKKIRLNTPLITAAMDTVTEARM 63
Query: 75 ARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKG 134
A A++ GG+G+IH N T+EQQA V VK NG I+ P +SP+ VS N+ ++
Sbjct: 64 AIAISREGGVGIIHKNMTIEQQADQVDRVKRSENGVIVNPFFLSPNHYVSDANNLMAKYK 123
Query: 135 ISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVERYPIKLEEAM 192
ISG+ + E KL+GI+ +D+ F +D S +++ MT REN+ LEEA
Sbjct: 124 ISGVPICEND----KLVGIITNRDLRFMTEQDYSQRIAEVMT-RENLVTAPVGTTLEEAQ 178
Query: 193 DVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKG 252
++L + + LP+++ + + L + +D +A YPNSS D+NG LLC AA
Sbjct: 179 EILRKHKIEKLPIVDGEGRLKGLITIKDIEKAVQYPNSSRDQNGRLLCGAAIGATPDVLE 238
Query: 253 RVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGA 312
RVA L +A +DVL LDS+ G+ V +R VKK YP ++++AGN+ T + AK LIDAGA
Sbjct: 239 RVAELVKAQVDVLALDSAHGHNSNVVETVRKVKKAYPDVQLIAGNIATAEAAKALIDAGA 298
Query: 313 DSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALA 372
D +++G+G GSIC T+ V G PQ TA+Y A A+ G+P +ADGG++ GD+ KALA
Sbjct: 299 DCIKVGIGPGSICTTRVVAGIGVPQITAVYDAACEASKYGIPVIADGGIKYSGDIVKALA 358
Query: 373 VGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQ 432
GANV M+GSMIAG E+P + G + K YRGMGS+ AM G S RY +
Sbjct: 359 AGANVVMIGSMIAGCEESPSDSEIYQGRQFKVYRGMGSLAAM--GHGSKDRYFQSDNKKL 416
Query: 433 VAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQ 492
V +GV G V KG++ + + GL+ G + + + K F + T
Sbjct: 417 VPEGVEGRVPYKGALSDTVFQMIGGLRAGMGYTGCGTIEELHAKA-----KFVKITGAGL 471
Query: 493 SEGAVHSLH 501
E H +
Sbjct: 472 KESHPHDIQ 480
>ref|NP_976337.1| inositol-5-monophosphate dehydrogenase [Bacillus cereus ATCC 10987]
ref|YP_081627.1| inositol-5-monophosphate dehydrogenase [Bacillus cereus E33L]
ref|ZP_02257621.1| inositol-5-monophosphate dehydrogenase [Bacillus cereus AH187]
ref|ZP_02599346.1| inositol-5-monophosphate dehydrogenase [Bacillus cereus H3081.97]
gb|AAS38945.1| inosine-5'-monophosphate dehydrogenase [Bacillus cereus ATCC 10987]
gb|AAU20220.1| IMP dehydrogenase (inositol-monophosphate dehydrogenase) [Bacillus
cereus E33L]
Length = 487
Score = 864 bits (2235), Expect = 0.0, Method: Composition-based stats.
Identities = 171/485 (35%), Positives = 272/485 (56%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F ++GL+F+D +++P D +V+V ++++ L++PL+S+ MDTVTE+ MA
Sbjct: 2 WESKFVKEGLTFDDVLLVPAKSDVLPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK +G I P ++P+ V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ V + KL+GI+ +D+ F++D S +S MT+ E + L+EA +L
Sbjct: 122 GVPVVNNLD-ERKLVGIITNRDMRFIQDYSIKISDVMTK-EQLITAPVGTTLDEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP++++ + L + +D + ++PNS+ D+ G LL AA R+ A
Sbjct: 180 KYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMTRIDA 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L +A +D +VLD++ G++ + ++ V+ YP L ++AGNV T + + LI+AGA+ ++
Sbjct: 240 LVKASVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAEATRALIEAGANVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A G+P +ADGG++ GD+ KALA GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
V MLGSM AG +E+PGE G + K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 VVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKG--SKDRYFQEGNKKLVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + +RE F R + E
Sbjct: 418 IEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQ-----FVRMSGAGLLESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHHVQ 477
>dbj|BAA88235.1| IMP dehydrogenase [Bacillus cereus]
Length = 509
Score = 864 bits (2234), Expect = 0.0, Method: Composition-based stats.
Identities = 172/485 (35%), Positives = 271/485 (55%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F ++GL+F+D +++P D +V+V ++++ L++PL+S+ MDTVTE+ MA
Sbjct: 2 WESKFVKEGLTFDDVLLVPARSDILPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK +G I P ++P+ V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ V + KL+GI+ +D+ F++D S +S MT+ E + LEEA +L
Sbjct: 122 GVPVVNNLD-ERKLVGIITNRDMRFIQDYSIKISDVMTK-EQLITAPVGTTLEEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP++++ + L + +D + ++PNS+ D+ G LL AA R+ A
Sbjct: 180 KYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAYLRIDA 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L +A +D +VLD++ G++ + ++ V+ YP L ++AGNV T + K LI+AG + ++
Sbjct: 240 LVKASVDAIVLDTAHGHSKGVIDKVKEVRAKYPSLNIIAGNVATAEATKALIEAGENVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A G+P +ADGG++ GD+ KALA GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
V MLGSM AG +E+PGE G + K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 VVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKG--SKDRYFQEGNKKLVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + +RE F R + E
Sbjct: 418 IEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQ-----FIRMSGAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHHVQ 477
>ref|ZP_01967358.1| hypothetical protein RUMTOR_00905 [Ruminococcus torques ATCC 27756]
gb|EDK25102.1| hypothetical protein RUMTOR_00905 [Ruminococcus torques ATCC 27756]
Length = 484
Score = 864 bits (2234), Expect = 0.0, Method: Composition-based stats.
Identities = 182/482 (37%), Positives = 275/482 (57%), Gaps = 12/482 (2%)
Query: 20 LFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARAMA 79
+G++F+D +++P + + ++V++S TK I L++P++S+ MDTVTE MA AMA
Sbjct: 3 KIIGEGITFDDVLLVPAYSEVIPNEVDLSTYLTKKIRLNIPMMSAGMDTVTEHRMAIAMA 62
Query: 80 LMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISGIL 139
GGIG+IH N ++E QA V VK NG I P +SP+ + N+ ++ ISG+
Sbjct: 63 RQGGIGIIHKNMSIEAQAEEVDKVKRSENGVITDPFYLSPENTLEDANNLMAKFRISGVP 122
Query: 140 VTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNRSR 199
+TE KL+GI+ +D+ F +D S + + MT E + + I LEEA VL ++R
Sbjct: 123 ITE----GRKLVGIITNRDLKFEEDFSKKIKESMTS-EGLITAKEGITLEEAKRVLAKAR 177
Query: 200 HGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAALSE 259
LP+++D+ + L + +D + YP S+ D G LLC AA RV AL +
Sbjct: 178 KEKLPIVDDEGNLTGLITIKDIEKQIKYPLSAKDSQGRLLCGAAIGITANCLERVDALVK 237
Query: 260 AGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRIGM 319
A +DV+V+DS+ G++ + +R VK+ YP L+V+AGNV T + AK LI+AG D++++G+
Sbjct: 238 AKVDVIVMDSAHGHSANVLRTVRMVKEKYPDLQVIAGNVATGEAAKALIEAGVDAVKVGI 297
Query: 320 GSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANVAM 379
G GSIC T+ V G PQ TA+ A GVP +ADGG++ GD+ KA+A GANV M
Sbjct: 298 GPGSICTTRVVAGIGVPQITAVMDCYNVAKEYGVPIIADGGIKYSGDMTKAIAAGANVCM 357
Query: 380 LGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGVAG 439
+GS+ AG E+PG + G + K YRGMGSI AM G S RY EN V +GV G
Sbjct: 358 MGSIFAGCDESPGTFELYQGRKYKVYRGMGSIAAMENG--SKDRYFQENAKKLVPEGVEG 415
Query: 440 AVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAVHS 499
V KG+V + + GL+ G + + ++ F + + + E H
Sbjct: 416 RVAYKGTVEDTVFQLMGGLRSGMGYCGTHTIEELKS-----NGRFIKISAASLKESHPHD 470
Query: 500 LH 501
+H
Sbjct: 471 IH 472
>ref|ZP_02234042.1| hypothetical protein DORFOR_00900 [Dorea formicigenerans ATCC
27755]
gb|EDR47817.1| hypothetical protein DORFOR_00900 [Dorea formicigenerans ATCC
27755]
Length = 484
Score = 864 bits (2233), Expect = 0.0, Method: Composition-based stats.
Identities = 173/482 (35%), Positives = 268/482 (55%), Gaps = 12/482 (2%)
Query: 20 LFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARAMA 79
+G++F+D +++P + + ++V++S TK I L++P++S+ MDTVTE MA AMA
Sbjct: 3 KIIGEGITFDDVLLVPAYSEVIPNQVDLSTYLTKKIHLNIPMMSAGMDTVTEHRMAIAMA 62
Query: 80 LMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISGIL 139
GGIG+IH N ++E QA V VK NG I P +SPD ++ + ++ ISG+
Sbjct: 63 RQGGIGIIHKNMSIEAQAEEVDRVKRSENGVITDPFYLSPDHTLADANELMAKFRISGVP 122
Query: 140 VTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNRSR 199
+TE GKL+GI+ +D+ F +D S + + MT E + I LEEA +L ++R
Sbjct: 123 ITEN----GKLVGIITNRDLKFEEDFSKKIKESMTS-EGLITAPEGITLEEAKRILAKAR 177
Query: 200 HGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAALSE 259
LP+++ + L + +D + YP ++ D G LLC AA R L
Sbjct: 178 KEKLPIVDKDFHLKGLITIKDIEKQIKYPLAAKDSQGRLLCGAAIGITANCIERAQELVN 237
Query: 260 AGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRIGM 319
A +DV+VLDS+ G++ + + +K +P L+V+AGNV T ++LI AGAD++++G+
Sbjct: 238 AKVDVVVLDSAHGHSANVIRTVDMIKSKFPDLQVIAGNVATGAATEDLIKAGADAVKVGI 297
Query: 320 GSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANVAM 379
G GSIC T+ + G PQ +A+ A G+P +ADGG++ GD+ KA+A GANV M
Sbjct: 298 GPGSICTTRIIAGIGVPQISAVMDCYEAADKYGIPIIADGGIKYSGDMTKAIAAGANVCM 357
Query: 380 LGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGVAG 439
+GS+ AG E+PG + G + K YRGMGSI AM G S RY + V +GV G
Sbjct: 358 MGSIFAGCDESPGTFELYQGRKYKVYRGMGSISAMENG--SKDRYFQTDAKKLVPEGVEG 415
Query: 440 AVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAVHS 499
V KGSV + + GL+ G + + ++EK F + + + E H
Sbjct: 416 RVAYKGSVEDTVFQLMGGLRSGMGYCGAPTIEDLKEK-----GRFVKISSASLKESHPHD 470
Query: 500 LH 501
+H
Sbjct: 471 IH 472
>gb|AAA36114.1| IMP dehydrogenase type 1 (EC 1.1.1.205)
Length = 514
Score = 863 bits (2232), Expect = 0.0, Method: Composition-based stats.
Identities = 264/505 (52%), Positives = 353/505 (69%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ D L++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 10 TGYVPEDGLTAQQLFASADDLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 70 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKNFEQGFITDPVVLSPSHTVGD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI +TE G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 130 VLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG+DV+V SSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 250 VGTREDDKYRLDLLTQAGVDVIVFHSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 310 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQT 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+D M + S KR
Sbjct: 370 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDPMEKSSSSQKR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 430 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++ Q EG VH LH YE++L+
Sbjct: 490 FEKRTMSPQIEGGVHGLHSYEKRLY 514
>ref|NP_829917.1| inositol-5-monophosphate dehydrogenase [Bacillus cereus ATCC 14579]
ref|ZP_02525234.1| inositol-5-monophosphate dehydrogenase [Bacillus cereus AH1134]
ref|ZP_02581397.1| inositol-5-monophosphate dehydrogenase [Bacillus cereus B4264]
gb|AAP07118.1| Inosine-5'-monophosphate dehydrogenase [Bacillus cereus ATCC 14579]
Length = 487
Score = 863 bits (2232), Expect = 0.0, Method: Composition-based stats.
Identities = 173/485 (35%), Positives = 272/485 (56%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F ++GL+F+D +++P D +V+V ++++ L++PL+S+ MDTVTE+ MA
Sbjct: 2 WESKFVKEGLTFDDVLLVPARSDILPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK +G I P ++P+ V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ V + KL+GI+ +D+ F++D S +S MT+ E + LEEA +L
Sbjct: 122 GVPVVNNLD-ERKLVGIITNRDMRFIQDYSIKISDVMTK-EQLITAPVGTTLEEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP++++ + L + +D + ++PNS+ D+ G LL AA R+ A
Sbjct: 180 KYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMLRIDA 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L +A +D +VLD++ G++ + ++ V+ YP L ++AGNV T + K LI+AGA+ ++
Sbjct: 240 LVKASVDAIVLDTAHGHSKGVIDKVKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A G+P +ADGG++ GD+ KALA GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
V MLGSM AG +E+PGE G + K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 VVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKG--SKDRYFQEGNKKLVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + +RE F R + E
Sbjct: 418 IEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQ-----FIRMSGAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHHVQ 477
>ref|YP_034368.1| inositol-5-monophosphate dehydrogenase [Bacillus thuringiensis
serovar konkukian str. 97-27]
gb|AAT58891.1| IMP dehydrogenase (inositol-monophosphate dehydrogenase) [Bacillus
thuringiensis serovar konkukian str. 97-27]
Length = 487
Score = 863 bits (2231), Expect = 0.0, Method: Composition-based stats.
Identities = 172/485 (35%), Positives = 271/485 (55%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F ++GL+F+D +++P D +V+V ++++ L++PL+S+ MDTVTE+ MA
Sbjct: 2 WESKFVKEGLTFDDVLLVPAKSDVLPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK +G I P ++P+ V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ V + KL+GI+ +D+ F++D S +S MT+ E + L EA +L
Sbjct: 122 GVPVVNNLD-ERKLVGIITNRDMRFIQDYSIKISDVMTK-EQLITAPVGTTLSEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP++++ + L + +D + ++PNS+ D+ G LL AA R+ A
Sbjct: 180 KYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMTRIDA 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L +A +D +VLD++ G++ + ++ V+ YP L ++AGNV T + K LI+AGA+ ++
Sbjct: 240 LVKASVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A G+P +ADGG++ GD+ KALA GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
V MLGSM AG +E+PGE G + K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 VVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKG--SKDRYFQEGNKKLVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + +RE F R + E
Sbjct: 418 IEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQ-----FVRMSGAGLLESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHHVQ 477
>ref|YP_002769495.1| inosine-5'-monophosphate dehydrogenase [Brevibacillus brevis NBRC
100599]
dbj|BAH40991.1| inosine-5'-monophosphate dehydrogenase [Brevibacillus brevis NBRC
100599]
Length = 486
Score = 863 bits (2231), Expect = 0.0, Method: Composition-based stats.
Identities = 177/484 (36%), Positives = 278/484 (57%), Gaps = 11/484 (2%)
Query: 18 EELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMARA 77
E+ F ++GL+F+D +++PG + V++ Q ++N+ L++PL+S+ MDTVTES +A A
Sbjct: 3 EDKFVKEGLTFDDVLLIPGKSEVLPRDVDLRVQLSENVKLNIPLISAGMDTVTESGLAIA 62
Query: 78 MALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGISG 137
MA GGIG++H N T+EQQA V VK +G I P S++ + V + + ISG
Sbjct: 63 MARQGGIGIVHKNMTIEQQASEVDRVKRSESGVITNPFSLTQEHTVEEANALMGKYRISG 122
Query: 138 ILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLNR 197
+ + + + KL+GI+ +D+ FV D S + + MT+ EN+ L++A +L +
Sbjct: 123 VPIVD---ANQKLIGILTNRDLRFVHDFSIKIKEVMTK-ENLVTAPVGTTLQQAELILQQ 178
Query: 198 SRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAAL 257
+ LP++++ + + L + +D +A YPN++ D G LLC AA R AAL
Sbjct: 179 HKIEKLPLVDENNTLRGLITIKDIEKAIQYPNAAKDNQGRLLCGAAVGVSADTFERAAAL 238
Query: 258 SEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLRI 317
+AG+DVLV+D++ G++ + ++ V+K YP L +VAGNV T + ++LI+AGA +++
Sbjct: 239 VQAGVDVLVIDTAHGHSKGVIETVKAVRKEYPTLTIVAGNVATGEATRDLIEAGASVVKV 298
Query: 318 GMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGANV 377
G+G GSIC T+ V G PQ TAI+ A+ A +P +ADGG++ GD+ KA+ GA+V
Sbjct: 299 GIGPGSICTTRVVAGIGVPQITAIHDCAQVAREYNIPIIADGGIKYSGDLPKAIGAGASV 358
Query: 378 AMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQGV 437
M+GS+ AGT E+PGE+ G R K YRGMGSI AM G S RY EN V +G+
Sbjct: 359 IMIGSLFAGTEESPGEFEIFQGRRFKVYRGMGSIGAMKAG--SKDRYFQENAQKLVPEGI 416
Query: 438 AGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGAV 497
G V KG + + + GL+ G + + + + F R T E
Sbjct: 417 EGRVPYKGPLADVTYQLIGGLRAGMGYCGAKTIEDLIQNSQ-----FVRITGAGLRESHP 471
Query: 498 HSLH 501
H +
Sbjct: 472 HDVQ 475
>ref|NP_842579.1| inositol-5-monophosphate dehydrogenase [Bacillus anthracis str.
Ames]
ref|YP_016613.1| inositol-5-monophosphate dehydrogenase [Bacillus anthracis str.
'Ames Ancestor']
ref|YP_026299.1| inositol-5-monophosphate dehydrogenase [Bacillus anthracis str.
Sterne]
ref|ZP_02217838.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0488]
ref|ZP_02393390.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0442]
ref|ZP_02400000.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0193]
ref|ZP_02543190.1| inositol-5-monophosphate dehydrogenase [Bacillus cereus W]
ref|ZP_02592998.1| inositol-5-monophosphate dehydrogenase [Bacillus cereus NVH0597-99]
ref|ZP_02605851.1| inositol-5-monophosphate dehydrogenase [Bacillus cereus 03BB108]
ref|ZP_02611793.1| inositol-5-monophosphate dehydrogenase [Bacillus anthracis
Tsiankovskii-I]
ref|ZP_02880117.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0465]
ref|ZP_02898001.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0389]
ref|ZP_02937002.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0174]
gb|AAP24065.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
Ames]
gb|AAT29088.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
'Ames Ancestor']
gb|AAT52350.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
Sterne]
gb|EDR16591.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0488]
gb|EDR85714.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0193]
gb|EDR92297.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0442]
gb|EDS96418.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0389]
gb|EDT17900.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0465]
gb|EDT65117.1| inosine-5'-monophosphate dehydrogenase [Bacillus anthracis str.
A0174]
Length = 487
Score = 862 bits (2229), Expect = 0.0, Method: Composition-based stats.
Identities = 172/485 (35%), Positives = 271/485 (55%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F ++GL+F+D +++P D +V+V ++++ L++PL+S+ MDTVTE+ MA
Sbjct: 2 WESKFVKEGLTFDDVLLVPAKSDVLPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK +G I P ++P+ V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ V + KL+GI+ +D+ F++D S +S MT+ E + L EA +L
Sbjct: 122 GVPVVNNLD-ERKLVGIITNRDMRFIQDYSIKISDVMTK-EQLITAPVGTTLSEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP++++ + L + +D + ++PNS+ D+ G LL AA R+ A
Sbjct: 180 KYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMTRIDA 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L +A +D +VLD++ G++ + ++ V+ YP L ++AGNV T + K LI+AGA+ ++
Sbjct: 240 LVKASVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A G+P +ADGG++ GD+ KALA GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
V MLGSM AG +E+PGE G + K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 VVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKG--SKDRYFQEGNKKLVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + +RE F R + E
Sbjct: 418 IEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQ-----FIRMSGAGLLESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHHVQ 477
>ref|YP_173515.1| inositol-5-monophosphate dehydrogenase [Bacillus clausii KSM-K16]
dbj|BAD62554.1| inosine-5'-monophosphate dehydrogenase [Bacillus clausii KSM-K16]
Length = 485
Score = 862 bits (2229), Expect = 0.0, Method: Composition-based stats.
Identities = 170/485 (35%), Positives = 274/485 (56%), Gaps = 11/485 (2%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F ++GL+F+D +++P + V+V+ + ++N+ L++P++S+ MDTVTES MA
Sbjct: 2 WETKFQKEGLTFDDVLLVPAKSEVLPRDVSVATKLSENVKLNIPILSAGMDTVTESEMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
A+A GGIG+IH N ++E+QA + VK +G I P ++PD V ++ + IS
Sbjct: 62 AIAREGGIGIIHKNMSIEEQAEQIDKVKRSESGVITDPFFLTPDRQVFDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ + + + KL+GI+ +D+ F++D S + MT+ E + LE+A +L
Sbjct: 122 GVPIVD---EEQKLVGILTNRDLRFIEDYSIKIDDVMTK-EGLVTAPVGTTLEQAEKILQ 177
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP+++D + L + +D + ++PNS+ D+ G LL AA R+AA
Sbjct: 178 QHKIEKLPLVDDNGILKGLITIKDIEKVIEFPNSAKDKQGRLLVGAAIGVSADADARIAA 237
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
+ +AG+D +V+D++ G++ + I+ V+ YP L ++AGNV T + + LI+AGA ++
Sbjct: 238 VVKAGVDAIVIDTAHGHSKGVLDKIKQVRNDYPDLTIIAGNVATAEGTRALIEAGASVVK 297
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A GVP +ADGG++ GD+ KALA G +
Sbjct: 298 VGIGPGSICTTRVVAGIGVPQITAVYDCATEARKHGVPIIADGGIKYSGDIVKALAAGGH 357
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
MLGS++AG SE+PGE G + K YRGMGS+ AM +G S RY EN V +G
Sbjct: 358 AVMLGSLLAGVSESPGETEIYQGRQYKVYRGMGSLGAMEKG--SKDRYFQENNQKLVPEG 415
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G KG + + + G++ G + D +RE F R T E
Sbjct: 416 IEGRTSYKGPLADTVHQLVGGIRAGMGYCGTPTIDELRENSQ-----FIRITAAGLRESH 470
Query: 497 VHSLH 501
H +
Sbjct: 471 PHDVQ 475
>ref|ZP_02039215.1| hypothetical protein BACCAP_04867 [Bacteroides capillosus ATCC
29799]
gb|EDM97342.1| hypothetical protein BACCAP_04867 [Bacteroides capillosus ATCC
29799]
Length = 491
Score = 862 bits (2229), Expect = 0.0, Method: Composition-based stats.
Identities = 179/487 (36%), Positives = 275/487 (56%), Gaps = 12/487 (2%)
Query: 15 TTAEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSM 74
T + F++ GL+F+D +++P D + +++ TK I L++PL+S+ MDTVTE M
Sbjct: 4 TDERQKFTKQGLTFDDVLLVPAESDVLPADIDLHTNLTKKIQLNIPLMSAAMDTVTEYRM 63
Query: 75 ARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKG 134
A A+A GGIG+IH N ++ QA V VK NG I P ++P ++ + ++
Sbjct: 64 AIAIAREGGIGIIHKNMSIGAQAEQVDMVKRSENGVITNPFWLAPGHTLAEADELMAKYR 123
Query: 135 ISGILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDV 194
ISG+ + + GKL+GI+ +D+ F D S + MT+ +++ + I LEEA ++
Sbjct: 124 ISGVPICDN----GKLIGIITNRDMKFETDMSQLIDNVMTK-DHLVTAKEGITLEEAKEI 178
Query: 195 LNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRV 254
L + + LP+++D + L + +D +A YPNS+ D G LL AA RV
Sbjct: 179 LRKHKIEKLPLVDDDFRLKGLITIKDIEKATVYPNSARDAKGRLLVGAAIGVTSDVLDRV 238
Query: 255 AALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADS 314
AAL EAG DVL LDS+ G++ + ++ +K YP ++++AGNV T + + LI+AGAD
Sbjct: 239 AALVEAGADVLCLDSAHGHSHNIIECVKRIKALYPDVQLIAGNVATAEGTRALIEAGADC 298
Query: 315 LRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVG 374
++IG+G GSIC T+ V G PQ TA+Y A A G+P +ADGG++ GD+ KA+A G
Sbjct: 299 VKIGIGPGSICTTRVVAGIGVPQITAVYDAACVADKYGIPIIADGGVKYSGDIAKAIAAG 358
Query: 375 ANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVA 434
ANV MLGS++AG E+PG+ G + K YRGMGS+ AM +G S RY +N V
Sbjct: 359 ANVVMLGSLLAGCEESPGDTEVYQGRQFKVYRGMGSLGAMAKG--SKDRYFQQNNKKLVP 416
Query: 435 QGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSE 494
+GV G V KGS + + GL+ G + +++K F + T E
Sbjct: 417 EGVEGRVPYKGSTSDTIYQMMGGLRAGMGYCGCATVSDLQKKAQ-----FIQITSAGLKE 471
Query: 495 GAVHSLH 501
H ++
Sbjct: 472 SHPHDVY 478
>sp|P50096|IMDH1_MOUSE Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1)
(IMPDH-I) (IMPD 1)
gb|AAA18285.1| type I inosine monophosphate dehydrogenase
Length = 514
Score = 861 bits (2227), Expect = 0.0, Method: Composition-based stats.
Identities = 267/505 (52%), Positives = 357/505 (70%), Gaps = 3/505 (0%)
Query: 7 RTKTLRDGTTAEELFSQ-DGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA ELF+ DGL++NDF+ILPGFIDF + +V+++ T+ I L PL+SSP
Sbjct: 10 TGYVPEDGLTAHELFANADGLTYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTE+ MA AMALMGGIG IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 70 MDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K + G SGI +T G KL+GIV ++DIDF KD + +S+ MT R + V
Sbjct: 130 VLEAKIQHGFSGIPITATGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRVELVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA ++L RS+ G LP++ND+DE+V + +R D + RDYP +S D + LLC AA
Sbjct: 190 AGVTLKEANEILQRSKKGKLPIVNDQDELVAIIARTDLKKNRDYPLASKDSHKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L++AG DV+V DSSQGN++YQ++ + ++K+ YPHL+V+ GNVVT Q
Sbjct: 250 VGTREDDKYRLDLLTQAGADVIVHDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D LR+GMG GSICITQEV+ACGRPQ TA+YKVA YA GVP +ADGG++
Sbjct: 310 AKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPVIADGGIQT 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRG+GS+DAM + S KR
Sbjct: 370 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGIGSLDAMEKSSSSQKR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + +++AQGV+G++ DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 430 YFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGAQSLSVLRSMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHYERKLF 508
F +RT++AQ EG VH LH YE++L+
Sbjct: 490 FEKRTMSAQIEGGVHGLHSYEKRLY 514
>ref|ZP_00743847.1| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis
serovar israelensis ATCC 35646]
ref|ZP_02587798.1| inositol-5-monophosphate dehydrogenase [Bacillus cereus G9842]
gb|EAO51882.1| Inosine-5'-monophosphate dehydrogenase [Bacillus thuringiensis
serovar israelensis ATCC 35646]
Length = 487
Score = 861 bits (2227), Expect = 0.0, Method: Composition-based stats.
Identities = 173/485 (35%), Positives = 272/485 (56%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F ++GL+F+D +++P D +V+V ++++ L++PL+S+ MDTVTE+ MA
Sbjct: 2 WESKFVKEGLTFDDVLLVPARSDILPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK +G I P ++P+ V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ V + KL+GI+ +D+ F++D S +S MT+ E + LEEA +L
Sbjct: 122 GVPVVNNLD-ERKLVGIITNRDMRFIQDYSIKISDVMTK-EQLITAPVGTTLEEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP++++ + L + +D + ++PNS+ D+ G LL AA R+ A
Sbjct: 180 KYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMLRIDA 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L +A +D +VLD++ G++ + ++ V+ YP L ++AGNV T + K LI+AGA+ ++
Sbjct: 240 LVKASVDAIVLDTAHGHSKGVIDKVKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A G+P +ADGG++ GD+ KALA GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGVKYSGDMVKALAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
V MLGSM AG +E+PGE G + K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 VVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKG--SKDRYFQEGNKKLVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + +RE F R + E
Sbjct: 418 IEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQ-----FIRMSGAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHHVQ 477
>ref|NP_001002177.1| hypothetical protein LOC431724 [Danio rerio]
gb|AAH74090.1| Zgc:91911 [Danio rerio]
emb|CAN87720.1| novel protein (zgc:91911) [Danio rerio]
gb|AAI65226.1| Zgc:91911 protein [synthetic construct]
Length = 544
Score = 861 bits (2226), Expect = 0.0, Method: Composition-based stats.
Identities = 276/500 (55%), Positives = 357/500 (71%), Gaps = 3/500 (0%)
Query: 7 RTKTLRDGTTAEELFS-QDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSP 65
DG TA++LF+ DGL++NDF+ILPGFIDF S +V+++ T+ I L PL+SSP
Sbjct: 10 TGYVPEDGLTAQQLFAIGDGLTYNDFLILPGFIDFISDEVDLTSALTRKITLKTPLISSP 69
Query: 66 MDTVTESSMARAMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVST 125
MDTVTESSMA AMALMGGIG+IH+NCT E QA VR VK + GFI P +SP V
Sbjct: 70 MDTVTESSMAIAMALMGGIGIIHHNCTPEFQANEVRKVKKFEQGFITDPVVMSPRHTVGD 129
Query: 126 IRNIKSEKGISGILVTEGGKYDGKLLGIVCTKDIDF--VKDASAPVSQYMTRRENMTVER 183
+ K G SGI VTE GK KL+GIV ++DIDF KD P+ + MT+RE++ V
Sbjct: 130 VFEAKVRHGFSGIPVTETGKMGSKLVGIVTSRDIDFLSEKDYDRPLEESMTKREDLVVAP 189
Query: 184 YPIKLEEAMDVLNRSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAA 243
+ L+EA D+L RS+ G LP++ND DE+V + +R D + RDYP +S D LLC AA
Sbjct: 190 AGVTLKEANDILQRSKKGKLPIVNDSDELVAIIARTDLKKNRDYPLASKDSRKQLLCGAA 249
Query: 244 TSTREADKGRVAALSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQ 303
TRE DK R+ L +AG+DV+VLDSSQGN+++Q+S I ++K+ YP L+VV GNVVT Q
Sbjct: 250 IGTREDDKYRLDLLMQAGVDVIVLDSSQGNSVFQISMINYIKQKYPELQVVGGNVVTAAQ 309
Query: 304 AKNLIDAGADSLRIGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRN 363
AKNLIDAG D+LR+GMG GSICITQEV+ACGRPQ T++YKVA YA GVP +ADGG++
Sbjct: 310 AKNLIDAGVDALRVGMGCGSICITQEVMACGRPQGTSVYKVAEYARRFGVPVIADGGIQT 369
Query: 364 VGDVCKALAVGANVAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKR 423
VG V KALA+GA+ M+GS++A T+E PGEYFF DG+RLK YRGMGS+DAM + S KR
Sbjct: 370 VGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKNNSSQKR 429
Query: 424 YLSENETLQVAQGVAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVL 483
Y SE + ++VAQGV+G+V DKGS+ K + Y+ G+Q QDIG S +R +Y G++
Sbjct: 430 YFSEGDKVKVAQGVSGSVQDKGSIHKFVPYLIAGIQHGCQDIGAKSLSILRSMMYSGELK 489
Query: 484 FNRRTLTAQSEGAVHSLHHY 503
F +RT++AQ EG VH LH Y
Sbjct: 490 FEKRTMSAQVEGGVHGLHSY 509
>ref|YP_001642905.1| inosine-5'-monophosphate dehydrogenase [Bacillus weihenstephanensis
KBAB4]
gb|ABY41277.1| inosine-5'-monophosphate dehydrogenase [Bacillus weihenstephanensis
KBAB4]
Length = 487
Score = 861 bits (2226), Expect = 0.0, Method: Composition-based stats.
Identities = 173/485 (35%), Positives = 272/485 (56%), Gaps = 9/485 (1%)
Query: 17 AEELFSQDGLSFNDFIILPGFIDFDSSKVNVSGQFTKNILLHLPLVSSPMDTVTESSMAR 76
E F ++GL+F+D +++P D +V+V ++++ L++PL+S+ MDTVTE+ MA
Sbjct: 2 WESKFVKEGLTFDDVLLVPARSDILPREVSVKTVLSESLQLNIPLISAGMDTVTEADMAI 61
Query: 77 AMALMGGIGVIHNNCTVEQQARMVRSVKLYRNGFIMKPKSVSPDVPVSTIRNIKSEKGIS 136
AMA GG+G+IH N ++EQQA V VK +G I P ++P+ V ++ + IS
Sbjct: 62 AMARQGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRIS 121
Query: 137 GILVTEGGKYDGKLLGIVCTKDIDFVKDASAPVSQYMTRRENMTVERYPIKLEEAMDVLN 196
G+ V + KL+GI+ +D+ F++D S +S MT+ E + LEEA +L
Sbjct: 122 GVPVVNNLD-ERKLVGIITNRDMRFIQDYSIKISDVMTK-EQLITAPVGTTLEEAEKILQ 179
Query: 197 RSRHGYLPVLNDKDEVVCLCSRRDAVRARDYPNSSLDRNGHLLCAAATSTREADKGRVAA 256
+ + LP++++ + L + +D + ++PNS+ D+ G LL AA R+ A
Sbjct: 180 KYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTADAMLRIDA 239
Query: 257 LSEAGIDVLVLDSSQGNTIYQVSFIRWVKKTYPHLEVVAGNVVTQDQAKNLIDAGADSLR 316
L +A +D +VLD++ G++ + ++ V+ YP L ++AGNV T + K LI+AGA+ ++
Sbjct: 240 LVKASVDAIVLDTAHGHSKGVIEKVKEVRAKYPALNIIAGNVATAEATKALIEAGANVVK 299
Query: 317 IGMGSGSICITQEVLACGRPQATAIYKVARYAASRGVPCVADGGLRNVGDVCKALAVGAN 376
+G+G GSIC T+ V G PQ TA+Y A A G+P +ADGG++ GD+ KALA GA+
Sbjct: 300 VGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKYGIPVIADGGVKYSGDMVKALAAGAH 359
Query: 377 VAMLGSMIAGTSETPGEYFFKDGMRLKGYRGMGSIDAMLQGRESGKRYLSENETLQVAQG 436
V MLGSM AG +E+PGE G + K YRGMGS+ AM +G S RY E V +G
Sbjct: 360 VVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKG--SKDRYFQEGNKKLVPEG 417
Query: 437 VAGAVLDKGSVLKLLAYIHKGLQQSAQDIGEVSFDAIREKVYEGQVLFNRRTLTAQSEGA 496
+ G V KG + + + GL+ G + +RE F R + E
Sbjct: 418 IEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQ-----FIRMSGAGLRESH 472
Query: 497 VHSLH 501
H +
Sbjct: 473 PHHVQ 477
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.315 0.202 0.717
Lambda K H
0.267 0.0616 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,799,504,588
Number of Sequences: 6899187
Number of extensions: 894354658
Number of successful extensions: 1922934
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 12839
Number of HSP's successfully gapped in prelim test: 10698
Number of HSP's that attempted gapping in prelim test: 1844549
Number of HSP's gapped (non-prelim): 47586
length of query: 512
length of database: 2,350,152,223
effective HSP length: 139
effective length of query: 373
effective length of database: 1,391,165,230
effective search space: 518904630790
effective search space used: 518904630790
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (20.9 bits)
S2: 82 (35.6 bits)