BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= AT1G68010__[Arabidopsis_thaliana]
         (386 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           6,899,187 sequences; 2,350,152,223 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|NP_176968.1|  HPR (HYDROXYPYRUVATE REDUCTASE); glycerate...   770   0.0  
dbj|BAA19751.1|  hydroxypyruvate reductase [Arabidopsis thal...   765   0.0  
emb|CAO47393.1|  unnamed protein product [Vitis vinifera]         704   0.0  
emb|CAN65023.1|  hypothetical protein [Vitis vinifera]            701   0.0  
gb|ABK96544.1|  unknown [Populus trichocarpa x Populus delto...   701   0.0  
dbj|BAB44155.1|  hydroxypyruvate reductase [Bruguiera gymnor...   697   0.0  
gb|ABL10359.1|  hydroxypyruvate reductase [Solenostemon scut...   696   0.0  
gb|AAO73867.1|AF503361_1  putative NADH-dependent hydroxypyr...   689   0.0  
gb|AAO73866.1|AF503360_1  putative NADH-dependent hydroxypyr...   688   0.0  
dbj|BAG09374.1|  peroxisomal hydroxypyruvate reductase [Glyc...   687   0.0  
sp|P13443|DHGY_CUCSA  Glycerate dehydrogenase (NADH-dependen...   683   0.0  
dbj|BAA08410.1|  hydroxypyruvate reductase [Cucurbita cv. Ku...   682   0.0  
dbj|BAA08411.1|  hydroxypyruvate reductase [Cucurbita cv. Ku...   675   0.0  
ref|NP_001045589.1|  Os02g0101500 [Oryza sativa (japonica cu...   665   0.0  
gb|ABK21250.1|  unknown [Picea sitchensis]                        664   0.0  
ref|XP_001784621.1|  predicted protein [Physcomitrella paten...   592   e-167
gb|EAY84074.1|  hypothetical protein OsI_005307 [Oryza sativ...   591   e-167
gb|EAZ21390.1|  hypothetical protein OsJ_004873 [Oryza sativ...   590   e-167
ref|XP_001752353.1|  predicted protein [Physcomitrella paten...   571   e-161
gb|ABD97861.1|  NADH-dependent hydroxypyruvate reductase [Pa...   563   e-159
gb|AAB00105.1|  NADH-dependent hydroxypyruvate reductase          484   e-135
ref|XP_001691480.1|  hydroxypyruvate reductase [Chlamydomona...   445   e-123
gb|AAW29979.1|  hydroxypyruvate reductase [Chlamydomonas rei...   393   e-107
gb|ABK55681.1|  NAPH-dependent hydroxypyruvate reductase [Cu...   342   2e-92
ref|YP_430795.1|  D-isomer specific 2-hydroxyacid dehydrogen...   252   3e-65
ref|YP_001410651.1|  Glyoxylate reductase [Fervidobacterium ...   241   9e-62
gb|ACB69759.1|  hydroxypyruvate reductase [Solanum lycopersi...   237   1e-60
ref|YP_001179183.1|  D-isomer specific 2-hydroxyacid dehydro...   229   3e-58
ref|YP_001471315.1|  D-isomer specific 2-hydroxyacid dehydro...   222   5e-56
ref|ZP_01666395.1|  D-isomer specific 2-hydroxyacid dehydrog...   222   5e-56
ref|ZP_01187992.1|  D-isomer specific 2-hydroxyacid dehydrog...   220   2e-55
ref|NP_623521.1|  glyoxylate reductase [Thermoanaerobacter t...   219   3e-55
emb|CAO81265.1|  glyoxylate reductase (glycolate:NAD+ oxidor...   215   4e-54
ref|YP_001568546.1|  D-isomer specific 2-hydroxyacid dehydro...   213   2e-53
ref|YP_001662713.1|  D-isomer specific 2-hydroxyacid dehydro...   211   8e-53
ref|YP_001664595.1|  D-isomer specific 2-hydroxyacid dehydro...   210   1e-52
ref|ZP_03856830.1|  lactate dehydrogenase-like oxidoreductas...   202   4e-50
ref|ZP_02943614.1|  D-isomer specific 2-hydroxyacid dehydrog...   201   1e-49
ref|YP_001306138.1|  D-isomer specific 2-hydroxyacid dehydro...   200   1e-49
ref|ZP_02129818.1|  Glyoxylate reductase [Desulfatibacillum ...   197   1e-48
ref|YP_848018.1|  D-isomer specific 2-hydroxyacid dehydrogen...   197   1e-48
emb|CAM32608.1|  Dehydrogenase oxidoreductase protein [Herba...   196   3e-48
ref|ZP_02836463.1|  D-isomer specific 2-hydroxyacid dehydrog...   196   3e-48
sp|Q9C4M5|GYAR_THELI  Glyoxylate reductase (Glycolate reduct...   196   3e-48
ref|NP_148197.2|  glyoxylate reductase [Aeropyrum pernix K1]...   194   8e-48
ref|ZP_02941201.1|  Glyoxylate reductase [Cyanothece sp. PCC...   194   1e-47
ref|NP_578048.1|  glyoxylate reductase [Pyrococcus furiosus ...   193   2e-47
ref|YP_001737977.1|  Glyoxylate reductase [Candidatus Korarc...   192   5e-47
ref|YP_643402.1|  D-isomer specific 2-hydroxyacid dehydrogen...   191   7e-47
ref|ZP_01439199.1|  2-hydroxyacid dehydrogenase [Fulvimarina...   191   9e-47
ref|YP_727037.1|  lactate dehydrogenase or related dehydroge...   189   3e-46
ref|YP_920227.1|  Glyoxylate reductase [Thermofilum pendens ...   189   4e-46
ref|YP_001853894.1|  glyoxylate reductase [Kocuria rhizophil...   189   4e-46
ref|ZP_01168688.1|  putative glycerate dehydrogenase [Bacill...   189   4e-46
ref|YP_704862.1|  probable glyoxylate reductase [Rhodococcus...   188   6e-46
ref|YP_001099124.1|  putative glyoxylate reductase (Glycolat...   187   8e-46
ref|YP_183096.1|  glyoxylate reductase [Thermococcus kodakar...   187   1e-45
ref|ZP_03905107.1|  lactate dehydrogenase-like oxidoreductas...   187   2e-45
ref|ZP_03960213.1|  glyoxylate reductase [Lactobacillus vagi...   186   3e-45
ref|ZP_02737749.1|  probable 2-hydroxyacid dehydrogenase [Ge...   185   5e-45
ref|YP_001352411.1|  2-hydroxyacid dehydrogenase [Janthinoba...   185   7e-45
ref|ZP_01368724.1|  D-isomer specific 2-hydroxyacid dehydrog...   184   7e-45
ref|YP_077041.1|  putative glycerate dehydrogenase [Symbioba...   184   9e-45
ref|NP_436410.1|  2-hydroxyacid dehydrogenase [Sinorhizobium...   183   2e-44
ref|YP_949816.1|  glyoxylate reductase [Arthrobacter auresce...   182   3e-44
ref|ZP_02913953.1|  Glyoxylate reductase [Geobacillus sp. WC...   182   3e-44
ref|ZP_01666712.1|  D-isomer specific 2-hydroxyacid dehydrog...   181   6e-44
ref|YP_517906.1|  hypothetical protein DSY1673 [Desulfitobac...   181   6e-44
ref|YP_971639.1|  D-isomer specific 2-hydroxyacid dehydrogen...   181   8e-44
ref|YP_001896547.1|  D-isomer specific 2-hydroxyacid dehydro...   181   1e-43
ref|YP_001155374.1|  D-isomer specific 2-hydroxyacid dehydro...   181   1e-43
ref|YP_001791021.1|  D-isomer specific 2-hydroxyacid dehydro...   181   1e-43
ref|NP_784530.1|  phosphoglycerate dehydrogenase [Lactobacil...   181   1e-43
ref|ZP_04014356.1|  possible glyoxylate reductase [Lactobaci...   181   1e-43
ref|ZP_02838365.1|  Glyoxylate reductase [Arthrobacter chlor...   180   1e-43
ref|ZP_03953531.1|  possible glyoxylate reductase [Lactobaci...   180   2e-43
ref|ZP_03941324.1|  possible glyoxylate reductase [Lactobaci...   180   2e-43
ref|ZP_03938310.1|  possible glyoxylate reductase [Lactobaci...   180   2e-43
ref|ZP_01521900.1|  D-isomer specific 2-hydroxyacid dehydrog...   179   4e-43
ref|YP_369265.1|  Gluconate 2-dehydrogenase [Burkholderia sp...   179   4e-43
ref|YP_346668.1|  2-hydroxyacid dehydrogenase [Pseudomonas f...   179   4e-43
ref|YP_809687.1|  Lactate dehydrogenase related enzyme [Oeno...   179   4e-43
ref|YP_001119514.1|  Gluconate 2-dehydrogenase [Burkholderia...   178   8e-43
ref|ZP_02463364.1|  gluconate 2-dehydrogenase [Burkholderia ...   177   9e-43
ref|YP_001696599.1|  Glyoxylate reductase [Lysinibacillus sp...   177   1e-42
ref|YP_001013056.1|  glyoxylate reductase [Hyperthermus buty...   177   1e-42
ref|YP_805502.1|  Lactate dehydrogenase related enzyme [Lact...   177   1e-42
ref|ZP_00982640.1|  COG1052: Lactate dehydrogenase and relat...   177   1e-42
ref|YP_001274602.1|  Glyoxylate reductase [Roseiflexus sp. R...   177   1e-42
ref|YP_626184.1|  Gluconate 2-dehydrogenase [Burkholderia ce...   177   1e-42
ref|ZP_01861538.1|  2-hydroxyacid dehydrogenase [Bacillus sp...   177   1e-42
gb|EAY61877.1|  Lactate dehydrogenase [Burkholderia cenocepa...   177   2e-42
ref|YP_001765034.1|  Gluconate 2-dehydrogenase [Burkholderia...   177   2e-42
ref|ZP_02481431.1|  gluconate 2-dehydrogenase [Burkholderia ...   177   2e-42
ref|YP_296488.1|  2-hydroxyacid dehydrogenase [Ralstonia eut...   176   2e-42
ref|YP_947693.1|  D-isomer specific 2-hydroxyacid dehydrogen...   176   2e-42
ref|ZP_02411121.1|  gluconate 2-dehydrogenase [Burkholderia ...   176   2e-42
ref|YP_559944.1|  Putative 2-ketogluconate reductase [Burkho...   176   3e-42
ref|ZP_02447221.1|  gluconate 2-dehydrogenase [Burkholderia ...   176   3e-42
ref|YP_001059129.1|  gluconate 2-dehydrogenase [Burkholderia...   176   3e-42
ref|YP_001328057.1|  D-isomer specific 2-hydroxyacid dehydro...   176   3e-42
ref|ZP_00986479.1|  COG1052: Lactate dehydrogenase and relat...   176   4e-42
ref|YP_108197.1|  2-ketogluconate reductase [Burkholderia ps...   176   4e-42
ref|ZP_02007136.1|  Gluconate 2-dehydrogenase [Ralstonia pic...   176   4e-42
ref|ZP_01764146.1|  gluconate 2-dehydrogenase [Burkholderia ...   176   4e-42
ref|YP_113865.1|  2-hydroxyacid dehydrogenase [Methylococcus...   176   4e-42
ref|ZP_01331240.1|  hypothetical protein BpseS_03000732 [Bur...   175   5e-42
ref|YP_001857046.1|  D-isomer specific 2-hydroxyacid dehydro...   175   5e-42
ref|ZP_02910943.1|  Gluconate 2-dehydrogenase [Burkholderia ...   175   6e-42
ref|ZP_02355535.1|  gluconate 2-dehydrogenase [Burkholderia ...   175   7e-42
ref|YP_056912.1|  D-isomer specific 2-hydroxyacid dehydrogen...   175   7e-42
ref|YP_001579713.1|  D-isomer specific 2-hydroxyacid dehydro...   175   7e-42
ref|YP_773543.1|  Gluconate 2-dehydrogenase [Burkholderia am...   175   7e-42
ref|YP_442819.1|  2-ketogluconate reductase [Burkholderia th...   174   1e-41
ref|YP_001434366.1|  Glyoxylate reductase [Roseiflexus caste...   174   1e-41
ref|YP_002782186.1|  glyoxylate reductase [Rhodococcus opacu...   174   1e-41
ref|YP_001808355.1|  Gluconate 2-dehydrogenase [Burkholderia...   174   1e-41
ref|YP_001020708.1|  putative 2-hydroxyacid dehydrogenase [M...   174   1e-41
ref|ZP_02893582.1|  Gluconate 2-dehydrogenase [Burkholderia ...   174   1e-41
ref|YP_001918184.1|  D-isomer specific 2-hydroxyacid dehydro...   174   1e-41
ref|YP_444791.1|  D-isomer specific 2-hydroxyacid dehydrogen...   173   2e-41
ref|YP_001104280.1|  glycerate dehydrogenase [Saccharopolysp...   173   2e-41
ref|YP_148818.1|  2-hydroxyacid dehydrogenase [Geobacillus k...   173   2e-41
ref|ZP_02464263.1|  2-hydroxyacid dehydrogenase [Burkholderi...   173   2e-41
ref|ZP_02373994.1|  glyoxylate reductase [Burkholderia thail...   173   2e-41
ref|YP_001540671.1|  D-isomer specific 2-hydroxyacid dehydro...   173   2e-41
ref|ZP_02387834.1|  glyoxylate reductase [Burkholderia thail...   173   3e-41
gb|ABD46560.1|  lactate dehydrogenase-like protein [Hartmann...   172   3e-41
ref|ZP_02887490.1|  D-isomer specific 2-hydroxyacid dehydrog...   172   3e-41
ref|YP_442235.2|  glyoxylate reductase [Burkholderia thailan...   172   3e-41
ref|YP_001118869.1|  D-isomer specific 2-hydroxyacid dehydro...   172   3e-41
gb|ABC36478.1|  glyoxylate reductase [Burkholderia thailande...   172   3e-41
gb|EEJ90696.1|  lactate dehydrogenase-like oxidoreductase [M...   172   4e-41
ref|YP_258132.1|  2-hydroxyacid dehydrogenase [Pseudomonas f...   172   4e-41
ref|YP_986727.1|  D-isomer specific 2-hydroxyacid dehydrogen...   172   5e-41
ref|YP_520253.1|  hypothetical protein DSY4020 [Desulfitobac...   171   7e-41
ref|ZP_01320783.1|  hypothetical protein BpseP_03005472 [Bur...   171   9e-41
ref|YP_002763306.1|  putative oxidoreductase [Gemmatimonas a...   171   9e-41
ref|ZP_02456664.1|  D-isomer specific 2-hydroxyacid dehydrog...   171   1e-40
ref|NP_867230.1|  probable 2-hydroxyacid dehydrogenase [Rhod...   171   1e-40
ref|YP_109051.1|  2-hydroxyacid dehydrogenase [Burkholderia ...   171   1e-40
ref|ZP_02114627.1|  D-isomer specific 2-hydroxyacid dehydrog...   171   1e-40
ref|YP_001067117.1|  D-isomer specific 2-hydroxyacid dehydro...   171   1e-40
ref|YP_001127005.1|  Glycerate dehydrogenase [Geobacillus th...   170   1e-40
ref|YP_001028734.1|  glyoxylate reductase [Burkholderia mall...   170   1e-40
gb|AAU49757.1|  glyoxylate reductase [Burkholderia mallei AT...   170   1e-40
ref|YP_993802.1|  glyoxylate reductase [Burkholderia mallei ...   170   1e-40
ref|YP_001565752.1|  D-isomer specific 2-hydroxyacid dehydro...   170   1e-40
ref|ZP_01104136.1|  glycerate dehydrogenase [gamma proteobac...   170   1e-40
ref|YP_268809.1|  putative glyoxylate reductase [Colwellia p...   170   2e-40
ref|ZP_02379512.1|  Gluconate 2-dehydrogenase [Burkholderia ...   170   2e-40
ref|ZP_02499004.1|  D-isomer specific 2-hydroxyacid dehydrog...   170   2e-40
ref|YP_273367.1|  D-isomer specific 2-hydroxyacid dehydrogen...   170   2e-40
ref|ZP_02403830.1|  glyoxylate reductase [Burkholderia pseud...   170   2e-40
ref|ZP_00829300.1|  COG1052: Lactate dehydrogenase and relat...   170   2e-40
ref|YP_001059830.1|  glyoxylate reductase [Burkholderia pseu...   170   2e-40
ref|ZP_02356479.1|  glyoxylate reductase [Burkholderia oklah...   169   2e-40
ref|ZP_02482681.1|  D-isomer specific 2-hydroxyacid dehydrog...   169   3e-40
ref|YP_080512.1|  D-isomer specific 2-hydroxyacid dehydrogen...   169   3e-40
ref|YP_234137.1|  2-hydroxyacid dehydrogenase [Pseudomonas s...   169   3e-40
ref|NP_645629.1|  hypothetical protein MW0812 [Staphylococcu...   169   3e-40
ref|YP_001488322.1|  gluconate 2-dehydrogenase [Bacillus pum...   169   3e-40
ref|NP_371454.1|  similar to glycerate dehydrogenase [Staphy...   169   4e-40
ref|YP_499419.1|  D-isomer specific 2-hydroxyacid dehydrogen...   169   4e-40
ref|ZP_00824069.1|  COG1052: Lactate dehydrogenase and relat...   169   5e-40
ref|ZP_02142939.1|  glyoxylate reductase [Roseobacter litora...   169   5e-40
ref|ZP_01447132.1|  2-hydroxyacid dehydrogenase [alpha prote...   168   6e-40
dbj|BAA29686.1|  376aa long hypothetical dehydrogenase [Pyro...   168   8e-40
ref|YP_684368.1|  glyoxylate reductase [Roseobacter denitrif...   167   9e-40
ref|YP_040314.1|  D-isomer specific 2-hydroxyacid dehydrogen...   167   9e-40
ref|YP_001318562.1|  D-isomer specific 2-hydroxyacid dehydro...   167   9e-40
ref|NP_764177.1|  glycerate dehydrogenase [Staphylococcus ep...   167   1e-39
ref|YP_848279.1|  D-isomer specific 2-hydroxyacid dehydrogen...   167   1e-39
ref|ZP_01012068.1|  D-isomer specific 2-hydroxyacid dehydrog...   167   1e-39
ref|YP_001190357.1|  Glyoxylate reductase [Metallosphaera se...   167   1e-39
ref|ZP_01878191.1|  D-isomer specific 2-hydroxyacid dehydrog...   167   1e-39
ref|NP_791047.1|  D-isomer specific 2-hydroxyacid dehydrogen...   167   1e-39
ref|YP_416286.1|  glycerate dehydrogenase [Staphylococcus au...   167   2e-39
ref|YP_301935.1|  putative dehydrogenase [Staphylococcus sap...   167   2e-39
ref|YP_001476295.1|  D-isomer specific 2-hydroxyacid dehydro...   167   2e-39
ref|NP_142561.2|  glyoxylate reductase [Pyrococcus horikoshi...   166   2e-39
ref|NP_693278.1|  glycerate dehydrogenase [Oceanobacillus ih...   166   2e-39
ref|ZP_02145180.1|  D-isomer specific 2-hydroxyacid dehydrog...   166   2e-39
ref|ZP_00953778.1|  D-isomer specific 2-hydroxyacid dehydrog...   166   2e-39
ref|YP_523399.1|  D-isomer specific 2-hydroxyacid dehydrogen...   166   2e-39
gb|AAS64128.1|  putative D-isomer specific 2-hydroxyaciddehy...   166   2e-39
ref|NP_407503.1|  2-hydroxyacid dehydrogenase [Yersinia pest...   166   3e-39
ref|YP_762106.1|  glyoxylate reductase [Hyphomonas neptunium...   166   3e-39
ref|YP_188108.1|  D-isomer specific 2-hydroxyacid dehydrogen...   166   3e-39
ref|ZP_02293529.1|  D-isomer specific 2-hydroxyacid dehydrog...   166   3e-39
ref|YP_001155168.1|  D-isomer specific 2-hydroxyacid dehydro...   166   3e-39
ref|YP_368457.1|  2-hydroxyacid dehydrogenase [Burkholderia ...   166   4e-39
ref|YP_046018.1|  2-keto-D-gluconate reductase (2-ketoaldona...   166   4e-39
ref|YP_253938.1|  hypothetical protein SH2023 [Staphylococcu...   166   4e-39
ref|YP_001764361.1|  D-isomer specific 2-hydroxyacid dehydro...   166   4e-39
ref|ZP_00982051.1|  COG1052: Lactate dehydrogenase and relat...   166   4e-39
ref|ZP_00948323.1|  D-isomer specific 2-hydroxyacid dehydrog...   165   5e-39
ref|ZP_01748801.1|  2-hydroxyacid dehydrogenase [Sagittula s...   165   5e-39
ref|YP_681501.1|  glyoxylate reductase [Roseobacter denitrif...   165   5e-39
ref|ZP_00833513.1|  COG1052: Lactate dehydrogenase and relat...   165   6e-39
ref|ZP_01741000.1|  D-isomer specific 2-hydroxyacid dehydrog...   165   6e-39
gb|AAM87639.1|AE014011_6  putative dehydrogenase [Yersinia p...   165   7e-39
ref|NP_422516.1|  2-hydroxyacid dehydrogenase [Caulobacter c...   165   7e-39
ref|ZP_02007695.1|  D-isomer specific 2-hydroxyacid dehydrog...   165   7e-39
ref|ZP_00416383.1|  D-isomer specific 2-hydroxyacid dehydrog...   164   8e-39
ref|YP_001686676.1|  Glyoxylate reductase [Caulobacter sp. K...   164   8e-39
ref|YP_649650.1|  D-isomer specific 2-hydroxyacid dehydrogen...   164   8e-39
ref|YP_620507.1|  D-isomer specific 2-hydroxyacid dehydrogen...   164   9e-39
ref|YP_610026.1|  D-isomer specific 2-hydroxyacid dehydrogen...   164   9e-39
ref|YP_001718784.1|  D-isomer specific 2-hydroxyacid dehydro...   164   9e-39
ref|ZP_00823666.1|  COG1052: Lactate dehydrogenase and relat...   164   9e-39
ref|NP_743421.1|  2-hydroxyacid dehydrogenase [Pseudomonas p...   164   1e-38
ref|NP_522506.1|  2-hydroxyacid dehydrogenase [Ralstonia sol...   164   1e-38
ref|NP_386583.1|  2-hydroxyacid dehydrogenase [Sinorhizobium...   164   1e-38
ref|NP_643033.1|  2-hydroxyacid dehydrogenase [Xanthomonas a...   164   1e-38
ref|ZP_01904616.1|  pyrroline-5-carboxylate reductase [Roseo...   164   1e-38
ref|ZP_02166865.1|  Glycolate reductase [Hoeflea phototrophi...   164   1e-38
ref|YP_001344468.1|  D-isomer specific 2-hydroxyacid dehydro...   164   1e-38
ref|YP_001269766.1|  D-isomer specific 2-hydroxyacid dehydro...   164   2e-38
ref|ZP_02153103.1|  D-isomer specific 2-hydroxyacid dehydrog...   164   2e-38
ref|ZP_00945493.1|  2-hydroxyacid dehydrogenase [Ralstonia s...   164   2e-38
ref|YP_001895899.1|  D-isomer specific 2-hydroxyacid dehydro...   163   2e-38
ref|ZP_01548851.1|  2-hydroxyacid dehydrogenase [Stappia agg...   163   2e-38
ref|NP_463611.1|  hypothetical protein lmo0078 [Listeria mon...   163   2e-38
ref|YP_996837.1|  D-isomer specific 2-hydroxyacid dehydrogen...   163   2e-38
ref|ZP_03821884.1|  lactate dehydrogenase [Acinetobacter sp....   163   2e-38
ref|YP_001903018.1|  Putative gluconate 2-dehydrogenase [Xan...   163   2e-38
ref|NP_637898.1|  2-hydroxyacid dehydrogenase [Xanthomonas c...   163   2e-38
ref|YP_001747738.1|  D-isomer specific 2-hydroxyacid dehydro...   163   3e-38
ref|ZP_01173412.1|  hypothetical protein B14911_09477 [Bacil...   162   3e-38
ref|ZP_01644816.1|  D-isomer specific 2-hydroxyacid dehydrog...   162   3e-38
ref|YP_001679796.1|  glyoxylate reductase [Heliobacterium mo...   162   3e-38
ref|ZP_02886343.1|  Gluconate 2-dehydrogenase [Burkholderia ...   162   3e-38
ref|YP_166811.1|  2-hydroxyacid dehydrogenase [Silicibacter ...   162   3e-38
ref|ZP_01035877.1|  D-isomer specific 2-hydroxyacid dehydrog...   162   4e-38
ref|YP_001488104.1|  D-isomer specific 2-hydroxyacid dehydro...   162   4e-38
ref|NP_252585.1|  probable 2-hydroxyacid dehydrogenase [Pseu...   162   4e-38
ref|YP_001670807.1|  D-isomer specific 2-hydroxyacid dehydro...   162   5e-38
ref|YP_364607.1|  2-hydroxyacid dehydrogenase [Xanthomonas c...   162   5e-38
ref|YP_001898481.1|  D-isomer specific 2-hydroxyacid dehydro...   162   5e-38
ref|ZP_00973664.1|  COG1052: Lactate dehydrogenase and relat...   162   5e-38
ref|ZP_02243841.1|  2-hydroxyacid dehydrogenase [Xanthomonas...   162   5e-38
ref|ZP_01696182.1|  D-isomer specific 2-hydroxyacid dehydrog...   162   6e-38
ref|YP_001842975.1|  phosphoglycerate dehydrogenase [Lactoba...   162   6e-38
ref|ZP_02308091.1|  D-isomer specific 2-hydroxyacid dehydrog...   162   6e-38
ref|ZP_00944908.1|  2-hydroxyacid dehydrogenase [Ralstonia s...   162   6e-38
ref|YP_789224.1|  putative D-isomer specific 2-hydroxyacid d...   162   6e-38
ref|ZP_00967857.1|  COG1052: Lactate dehydrogenase and relat...   161   7e-38
ref|ZP_03944319.1|  glyoxylate reductase [Lactobacillus ferm...   161   8e-38
ref|ZP_00232760.1|  D-isomer specific 2-hydroxyacid dehydrog...   161   8e-38
ref|YP_001862903.1|  D-isomer specific 2-hydroxyacid dehydro...   161   8e-38
ref|ZP_02276086.1|  D-isomer specific 2-hydroxyacid dehydrog...   161   9e-38
ref|ZP_01448595.1|  2-hydroxyacid dehydrogenase [alpha prote...   161   9e-38
ref|YP_012706.1|  D-isomer specific 2-hydroxyacid dehydrogen...   161   1e-37
ref|ZP_02319032.1|  D-isomer specific 2-hydroxyacid dehydrog...   161   1e-37
ref|NP_244180.1|  glycerate dehydrogenase [Bacillus halodura...   160   1e-37
ref|ZP_00230005.1|  D-isomer specific 2-hydroxyacid dehydrog...   160   1e-37
ref|ZP_01942633.1|  hypothetical protein LMSG_02191 [Listeri...   160   1e-37
ref|NP_519155.1|  2-hydroxyacid dehydrogenase [Ralstonia sol...   160   1e-37
ref|ZP_02989735.1|  D-isomer specific 2-hydroxyacid dehydrog...   160   1e-37
ref|YP_001857480.1|  D-isomer specific 2-hydroxyacid dehydro...   160   1e-37
ref|YP_001008293.1|  putative D-isomer specific 2-hydroxyaci...   160   1e-37
gb|AAT51138.1|  PA3896 [synthetic construct]                      160   2e-37
ref|ZP_00985869.1|  COG1052: Lactate dehydrogenase and relat...   160   2e-37
ref|YP_001898275.1|  Gluconate 2-dehydrogenase [Ralstonia pi...   160   2e-37
ref|YP_584592.1|  D-isomer specific 2-hydroxyacid dehydrogen...   160   2e-37
ref|ZP_01926074.1|  hypothetical protein LMHG_01678 [Listeri...   160   2e-37
sp|P58000|TKRA_ENTAG  2-ketogluconate reductase (2KR) (2-ket...   160   2e-37
ref|YP_259824.1|  2-ketogluconate 6-phosphate reductase, put...   160   2e-37
ref|ZP_01931502.1|  hypothetical protein LMIG_00356 [Listeri...   159   3e-37
ref|YP_348635.1|  D-isomer specific 2-hydroxyacid dehydrogen...   159   3e-37
pdb|2DBQ|A  Chain A, Crystal Structure Of Glyoxylate Reducta...   159   3e-37
ref|YP_886866.1|  glyoxylate reductase [Mycobacterium smegma...   159   3e-37
ref|YP_001346594.1|  probable 2-hydroxyacid dehydrogenase [P...   159   4e-37
ref|NP_126444.1|  phosphoglycerate dehydrogenase (serA), Nte...   159   4e-37
ref|ZP_02689071.1|  D-isomer specific 2-hydroxyacid dehydrog...   159   4e-37
ref|ZP_00961432.1|  D-isomer specific 2-hydroxyacid dehydrog...   159   5e-37
ref|YP_001040569.1|  D-isomer specific 2-hydroxyacid dehydro...   159   5e-37
ref|YP_001749434.1|  D-isomer specific 2-hydroxyacid dehydro...   159   5e-37
ref|ZP_01723234.1|  hypothetical protein BB14905_20250 [Baci...   159   5e-37
ref|ZP_00997972.1|  D-isomer specific 2-hydroxyacid dehydrog...   158   5e-37
ref|ZP_01446951.1|  Glycolate reductase [alpha proteobacteri...   158   5e-37
ref|YP_981857.1|  D-isomer specific 2-hydroxyacid dehydrogen...   158   6e-37
ref|YP_795642.1|  Lactate dehydrogenase related enzyme [Lact...   158   6e-37
ref|ZP_01755592.1|  D-isomer specific 2-hydroxyacid dehydrog...   158   6e-37
ref|ZP_01755871.1|  glycerate dehydrogenase [Roseobacter sp....   158   7e-37
ref|ZP_01444314.1|  2-hydroxyacid dehydrogenase [Roseovarius...   158   8e-37
ref|ZP_01750929.1|  D-isomer specific 2-hydroxyacid dehydrog...   158   8e-37
ref|YP_001909347.1|  2-ketogluconate reductase [Erwinia tasm...   158   8e-37
ref|ZP_02139703.1|  D-isomer specific 2-hydroxyacid dehydrog...   158   9e-37
ref|YP_612620.1|  D-isomer specific 2-hydroxyacid dehydrogen...   158   9e-37
ref|ZP_02286033.1|  D-isomer specific 2-hydroxyacid dehydrog...   157   9e-37
ref|YP_001847108.1|  Lactate dehydrogenase [Acinetobacter ba...   157   1e-36
ref|YP_894127.1|  2-hydroxyacid dehydrogenase family protein...   157   1e-36
ref|YP_001706749.1|  2-keto-D-gluconate reductase (2-ketoald...   157   1e-36
ref|ZP_01741677.1|  glycerate dehydrogenase [Rhodobacterales...   157   1e-36
ref|NP_469416.1|  hypothetical protein lin0070 [Listeria inn...   157   1e-36
ref|YP_559036.1|  Putative 2-ketogluconate 6-phosphate reduc...   157   1e-36
ref|YP_001713205.1|  2-keto-D-gluconate reductase (2-ketoald...   157   1e-36
ref|NP_693770.1|  2-ketogluconate reductase [Oceanobacillus ...   157   2e-36
>ref|NP_176968.1| HPR (HYDROXYPYRUVATE REDUCTASE); glycerate dehydrogenase/ poly(U)
           binding [Arabidopsis thaliana]
 gb|AAG52006.1|AC012563_16 hydroxypyruvate reductase (HPR); 50972-48670 [Arabidopsis thaliana]
 gb|AAK44036.1|AF370221_1 putative hydroxypyruvate reductase HPR [Arabidopsis thaliana]
 gb|AAM20404.1| hydroxypyruvate reductase (HPR) [Arabidopsis thaliana]
 gb|AAM44919.1| putative hydroxypyruvate reductase [Arabidopsis thaliana]
 gb|AAN65124.1| hydroxypyruvate reductase (HPR) [Arabidopsis thaliana]
 dbj|BAE98694.1| hydroxypyruvate reductase [Arabidopsis thaliana]
          Length = 386

 Score =  770 bits (1987), Expect = 0.0,   Method: Composition-based stats.
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG
Sbjct: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL
Sbjct: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENASPPNASPSIVNSKALGLPVSKL
Sbjct: 361 NENASPPNASPSIVNSKALGLPVSKL 386
>dbj|BAA19751.1| hydroxypyruvate reductase [Arabidopsis thaliana]
          Length = 386

 Score =  765 bits (1975), Expect = 0.0,   Method: Composition-based stats.
 Identities = 384/386 (99%), Positives = 384/386 (99%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG
Sbjct: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVI EAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIHEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEPFMKPGLAD KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL
Sbjct: 301 EEPFMKPGLADMKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENASPPNASPSIVNSKALGLPVSKL
Sbjct: 361 NENASPPNASPSIVNSKALGLPVSKL 386
>emb|CAO47393.1| unnamed protein product [Vitis vinifera]
          Length = 418

 Score =  704 bits (1816), Expect = 0.0,   Method: Composition-based stats.
 Identities = 343/380 (90%), Positives = 367/380 (96%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP GKYRVVSTKPMPGTRWI+LLV Q CRVEIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPCGKYRVVSTKPMPGTRWIDLLVQQDCRVEICTQKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALS+AGG+AFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSRAGGRAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLS+AAARRIVEADEFMR GLY+GWLPHLFVGNLL+GQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSMAAARRIVEADEFMRAGLYDGWLPHLFVGNLLRGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQ+TRLEKFVTAYGQFLKA+GEQPVTWKRA+SM+EVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYYDLYQATRLEKFVTAYGQFLKASGEQPVTWKRAASMDEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERL+MMKKEAIL+NCSRGPVIDE ALV HLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLSMMKKEAILINCSRGPVIDEVALVAHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG++KGYPIWHDPN+V+PFL
Sbjct: 301 DEPYMKPGLAEMKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPIWHDPNKVEPFL 360

Query: 361 NENASPPNASPSIVNSKALG 380
           NEN+ PP ASPSIVN+KALG
Sbjct: 361 NENSLPPAASPSIVNAKALG 380
>emb|CAN65023.1| hypothetical protein [Vitis vinifera]
          Length = 386

 Score =  701 bits (1810), Expect = 0.0,   Method: Composition-based stats.
 Identities = 342/379 (90%), Positives = 366/379 (96%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP GKYRVVSTKPMPGTRWI+LLV Q CRVEIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPCGKYRVVSTKPMPGTRWIDLLVQQDCRVEICTQKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALS+AGG+AFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSRAGGRAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLS+AAARRIVEADEFMR GLY+GWLPHLFVGNLL+GQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSMAAARRIVEADEFMRAGLYDGWLPHLFVGNLLRGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQ+TRLEKFVTAYGQFLKA+GEQPVTWKRA+SM+EVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYYDLYQATRLEKFVTAYGQFLKASGEQPVTWKRAASMDEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERL+MMKKEAIL+NCSRGPVIDE ALV HLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLSMMKKEAILINCSRGPVIDEVALVAHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG++KGYPIWHDPN+V+PFL
Sbjct: 301 DEPYMKPGLAEMKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPIWHDPNKVEPFL 360

Query: 361 NENASPPNASPSIVNSKAL 379
           NEN+ PP ASPSIVN+KAL
Sbjct: 361 NENSLPPAASPSIVNAKAL 379
>gb|ABK96544.1| unknown [Populus trichocarpa x Populus deltoides]
          Length = 386

 Score =  701 bits (1809), Expect = 0.0,   Method: Composition-based stats.
 Identities = 345/386 (89%), Positives = 371/386 (96%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEVYNPNGKYRVVSTK MPGTRWINLL++Q CRVEIC  KKTILSVEDII LIG
Sbjct: 1   MAKPISIEVYNPNGKYRVVSTKSMPGTRWINLLIEQDCRVEICTQKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLF+ALS+AGGKAFSNMAVGYNNVDV AANK+G+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFAALSRAGGKAFSNMAVGYNNVDVNAANKHGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEAD+FMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAYG+FLKANGEQPVTWKRA+SM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYGEFLKANGEQPVTWKRAASMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHP+LDKTTYHL+NKE LA MKKEAILVNCSRGPV+DE ALVEHLK+NPMFRVGLDVFE
Sbjct: 241 SLHPILDKTTYHLINKESLATMKKEAILVNCSRGPVVDEVALVEHLKQNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNA+VVPHIASASKWTREGMATLAALNVLG++KGYP+W DPN+V PFL
Sbjct: 301 DEPYMKPGLADMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGDPNQVAPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP ASPSIVN+KALGLPVSKL
Sbjct: 361 NENAPPPAASPSIVNAKALGLPVSKL 386
>dbj|BAB44155.1| hydroxypyruvate reductase [Bruguiera gymnorrhiza]
          Length = 386

 Score =  697 bits (1799), Expect = 0.0,   Method: Composition-based stats.
 Identities = 346/386 (89%), Positives = 369/386 (95%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP G+YRVVSTKPMPGTRWINLLV Q CR+EIC  KKTILSVEDII L+G
Sbjct: 1   MAKPVSIEVWNPRGRYRVVSTKPMPGTRWINLLVQQDCRLEICTEKKTILSVEDIIALMG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLF+ALSKAGGKAFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFAALSKAGGKAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR GLY+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGLYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQ+TRLEKFVTAYGQFLKANGEQPVTWKRA++M+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQATRLEKFVTAYGQFLKANGEQPVTWKRAATMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHL+NKE LA MKKEA+LVNCSRGPVIDE ALVEHL+ NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLINKESLASMKKEAVLVNCSRGPVIDEVALVEHLRRNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAIVVPHIASASKWTREGMATLAALNVLG++KGYP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGDPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP A PSIVNSKALGLPVSKL
Sbjct: 361 NENAPPPAACPSIVNSKALGLPVSKL 386
>gb|ABL10359.1| hydroxypyruvate reductase [Solenostemon scutellarioides]
          Length = 386

 Score =  696 bits (1797), Expect = 0.0,   Method: Composition-based stats.
 Identities = 346/386 (89%), Positives = 366/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+ +EVYNPNGKYRVVSTK MPGTRWINLLVDQ CR+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPLQVEVYNPNGKYRVVSTKSMPGTRWINLLVDQDCRLEICTEKKTILSVEDIISLIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           +KCDGVIGQLTEDWGE LFSALS+AGG AFSNMAVGYNNVDV+AANK+G+AVGNTPGVLT
Sbjct: 61  NKCDGVIGQLTEDWGEKLFSALSRAGGTAFSNMAVGYNNVDVDAANKHGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAYGQFL+ANGEQPVTWKRASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYGQFLQANGEQPVTWKRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAILVNCSRGPVIDE ALVEHLK+NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILVNCSRGPVIDEVALVEHLKQNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGL   KNAI+VPHIASASKWTREGMATLAALNVLG++KGYPIW DPN V PFL
Sbjct: 301 DEPYMKPGLEKMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPIWGDPNNVAPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NEN+ PP A PSIVNSKALGLPVSKL
Sbjct: 361 NENSPPPAACPSIVNSKALGLPVSKL 386
>gb|AAO73867.1|AF503361_1 putative NADH-dependent hydroxypyruvate reductase [Glycine max]
          Length = 386

 Score =  689 bits (1777), Expect = 0.0,   Method: Composition-based stats.
 Identities = 344/386 (89%), Positives = 365/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP+GKYRVVSTKPMPGTRWINLL+    R+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPSGKYRVVSTKPMPGTRWINLLIQNDVRLEICTEKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALSKAGGKAFSNMAVGYNNVDV+AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEELFSALSKAGGKAFSNMAVGYNNVDVDAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASL+LAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLTLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAY  FLKANGE PVTWKRA++M+EVL+EAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYAAFLKANGETPVTWKRAATMDEVLQEADII 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAIL+NCSRGPVIDEAALVEHLK NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILINCSRGPVIDEAALVEHLKHNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG+VKGYP+W D NRV+PFL
Sbjct: 301 EEPYMKPGLAELKNAIVVPHIASASKWTREGMATLAALNVLGKVKGYPVWFDANRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP A PSIVN+KALGLP SKL
Sbjct: 361 NENARPPAACPSIVNAKALGLPTSKL 386
>gb|AAO73866.1|AF503360_1 putative NADH-dependent hydroxypyruvate reductase [Glycine max]
          Length = 386

 Score =  688 bits (1776), Expect = 0.0,   Method: Composition-based stats.
 Identities = 343/386 (88%), Positives = 366/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP+GKYRVVSTKPMPGTRWINLLV    R+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPSGKYRVVSTKPMPGTRWINLLVQNDVRLEICTEKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFS LSKAGGKAFSNMAVGYNNVDV+AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEQLFSTLSKAGGKAFSNMAVGYNNVDVDAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKF+TAY  FLKA+GE PVTWKRA++M+EVL+EAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFITAYATFLKASGETPVTWKRAATMDEVLQEADII 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAIL+NCSRGPVIDEAALVEHLK+NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILINCSRGPVIDEAALVEHLKQNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG++KGYP+W D NRV+PFL
Sbjct: 301 EEPYMKPGLAELKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPVWFDANRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP ASPSIVN+KALGLP SKL
Sbjct: 361 NENAQPPAASPSIVNAKALGLPTSKL 386
>dbj|BAG09374.1| peroxisomal hydroxypyruvate reductase [Glycine max]
          Length = 386

 Score =  687 bits (1773), Expect = 0.0,   Method: Composition-based stats.
 Identities = 343/386 (88%), Positives = 365/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP+GKYRVVSTKPMPGTRWINLL+    R+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPSGKYRVVSTKPMPGTRWINLLIQNDVRLEICTEKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALSKAGGKAFSNMAVGYNNVDV+AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEELFSALSKAGGKAFSNMAVGYNNVDVDAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASL+LAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLTLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAY  FLKANGE PVTWKRA++M+EVL+EAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYAAFLKANGETPVTWKRAATMDEVLQEADII 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAIL+NCSRGPVIDEAALVEHLK NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILINCSRGPVIDEAALVEHLKHNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG+VKGYP+W D N+V+PFL
Sbjct: 301 EEPYMKPGLAELKNAIVVPHIASASKWTREGMATLAALNVLGKVKGYPVWFDANKVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP A PSIVN+KALGLP SKL
Sbjct: 361 NENARPPAACPSIVNAKALGLPTSKL 386
>sp|P13443|DHGY_CUCSA Glycerate dehydrogenase (NADH-dependent hydroxypyruvate reductase)
           (HPR) (GDH)
 emb|CAA41434.1| NADH-dependent hydroxypyruvate reductase [Cucumis sativus]
 emb|CAA32764.1| unnamed protein product [Cucumis sativus]
          Length = 382

 Score =  683 bits (1763), Expect = 0.0,   Method: Composition-based stats.
 Identities = 336/380 (88%), Positives = 363/380 (95%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPV IEV+NPNGKYRVVSTKPMPGTRWINLL++Q CRVEIC  KKTILSVEDI+ LIG
Sbjct: 1   MAKPVQIEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDILALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALS+AGGKAFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEVLFSALSRAGGKAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR G Y+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGRYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEAPVTWRRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTT+HLVNKE L  MKK+AIL+NCSRGPVIDEAALV+HL++NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAI+VPHIASASKWTREGMATLAALNVLG++KGYP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPVWSDPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALG 380
           +EN SPP ASPSIVN+KALG
Sbjct: 361 DENVSPPAASPSIVNAKALG 380
>dbj|BAA08410.1| hydroxypyruvate reductase [Cucurbita cv. Kurokawa Amakuri]
          Length = 386

 Score =  682 bits (1760), Expect = 0.0,   Method: Composition-based stats.
 Identities = 340/386 (88%), Positives = 364/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MA  V +EV+NPNGKYRVVSTKPMPGTRWINLL++Q CRVEIC  KKTILSVEDI+ LIG
Sbjct: 1   MANRVQVEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDIVALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALS+AG KAFSNMAVGYNNVDV AANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEVLFSALSRAGCKAFSNMAVGYNNVDVNAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR G Y+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGHYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEVPVTWRRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTT+HLVNKE L  MKK+AIL+NCSRGPVIDEAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAI+VPHIASASKWTREGMATLAALNVLG++K YP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKQYPVWADPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           +ENA PP ASPSIVN+KAL LPVSKL
Sbjct: 361 DENAPPPAASPSIVNAKALELPVSKL 386
>dbj|BAA08411.1| hydroxypyruvate reductase [Cucurbita cv. Kurokawa Amakuri]
          Length = 381

 Score =  675 bits (1741), Expect = 0.0,   Method: Composition-based stats.
 Identities = 335/381 (87%), Positives = 360/381 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MA  V +EV+NPNGKYRVVSTKPMPGTRWINLL++Q CRVEIC  KKTILSVEDI+ LIG
Sbjct: 1   MANRVQVEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDIVALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALS+AG KAFSNMAVGYNNVDV AANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEVLFSALSRAGCKAFSNMAVGYNNVDVNAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR G Y+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGHYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEVPVTWRRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTT+HLVNKE L  MKK+AIL+NCSRGPVIDEAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAI+VPHIASASKWTREGMATLAALNVLG++K YP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKQYPVWADPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGL 381
           +ENA PP ASPSIVN+KALG+
Sbjct: 361 DENAPPPAASPSIVNAKALGI 381
>ref|NP_001045589.1| Os02g0101500 [Oryza sativa (japonica cultivar-group)]
 dbj|BAD07805.1| putative hydroxypyruvate reductase [Oryza sativa Japonica Group]
 dbj|BAD08188.1| putative hydroxypyruvate reductase [Oryza sativa Japonica Group]
 dbj|BAF07503.1| Os02g0101500 [Oryza sativa (japonica cultivar-group)]
          Length = 386

 Score =  665 bits (1717), Expect = 0.0,   Method: Composition-based stats.
 Identities = 328/386 (84%), Positives = 360/386 (93%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEV+NP+GKYRVVSTK MPGTRWI LL D  CR+EIC   KTILSV+DI+ LIG
Sbjct: 1   MAKPISIEVWNPSGKYRVVSTKSMPGTRWIRLLADNDCRLEICTETKTILSVDDILALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           D+CDGVIGQLTE+WGE LFSAL +AGG AFSNMAVGYNNVDVEAAN+ GIAVGNTPGVLT
Sbjct: 61  DRCDGVIGQLTEEWGEVLFSALKRAGGTAFSNMAVGYNNVDVEAANRNGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEAD+FMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMM+EGFKMNLIY+DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRA++ME+VLREAD+I
Sbjct: 181 ARMMIEGFKMNLIYYDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRAATMEDVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHL+N ERLA+MKKEA+LVN SRGPVIDE ALVEHLK NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLINPERLAIMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNA+VVPHIASASKWTREGMATLAALNVLG++KGYP+W +PN V+PFL
Sbjct: 301 DEPYMKPGLADMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNLVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
            E+A+PP A PSIVN+K LGLP SKL
Sbjct: 361 KEDATPPAACPSIVNAKQLGLPSSKL 386
>gb|ABK21250.1| unknown [Picea sitchensis]
          Length = 386

 Score =  664 bits (1712), Expect = 0.0,   Method: Composition-based stats.
 Identities = 312/386 (80%), Positives = 355/386 (91%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEV+NP GK+RVVSTK MPGTRWI LL D  CR+EIC  KKTIL VEDI  LIG
Sbjct: 1   MAKPISIEVWNPAGKHRVVSTKSMPGTRWIRLLTDADCRLEICTEKKTILDVEDIQALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFS L +AGG AFSNMAVGYNNVD+ AAN YGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSTLKRAGGTAFSNMAVGYNNVDLNAANTYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELA +L+++A+RR+VEAD+FMR GLY+GWLPHLFVGNLLKGQTVG+IGAGRIGSAY
Sbjct: 121 ETTAELAVALTVSASRRVVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGIIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEK++TAYG+FLK+ GE PVTWKRAS+ E+VLR+AD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKYMTAYGEFLKSQGEAPVTWKRASTAEDVLRDADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHP+LDKTTYHL+NK+RL++MKKEA+LVN SRGPVIDEAALV HLK NPMFRVGLDVFE
Sbjct: 241 SLHPILDKTTYHLINKDRLSIMKKEAVLVNASRGPVIDEAALVNHLKANPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLA+ KNA+VVPHIASASKWTREGMATLAALNVLG+VKGYP+W D N+++PFL
Sbjct: 301 DEPYMKPGLAEQKNAVVVPHIASASKWTREGMATLAALNVLGKVKGYPVWPDANKLEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           +EN++PP A PSIVN+K LGL VSKL
Sbjct: 361 DENSAPPAACPSIVNAKLLGLEVSKL 386
>ref|XP_001784621.1| predicted protein [Physcomitrella patens subsp. patens]
 gb|EDQ50553.1| predicted protein [Physcomitrella patens subsp. patens]
          Length = 391

 Score =  592 bits (1526), Expect = e-167,   Method: Composition-based stats.
 Identities = 294/382 (76%), Positives = 338/382 (88%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MA+ ++++VYN  G  RVVSTKPMPG +WI  L   GCRVE+C   KTILSV+DI+ LIG
Sbjct: 1   MARKLAVQVYNAGGHLRVVSTKPMPGNQWIQALTSVGCRVEVCVENKTILSVDDILSLIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
            KCDGVIGQLTEDWG+ LF+AL KAGG A+SNMAVGYNNVDVEAA ++GIAVGNTPGVLT
Sbjct: 61  TKCDGVIGQLTEDWGDVLFAALKKAGGHAYSNMAVGYNNVDVEAATRHGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAA+L+L+AARR+VEAD+FMR G YEGWLP LFVGNLLKGQTVG+IGAGRIG+AY
Sbjct: 121 ETTAELAAALTLSAARRVVEADDFMRAGKYEGWLPTLFVGNLLKGQTVGIIGAGRIGTAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMN+IY+DLYQSTRLEKFVTAYG+FLK  GE PV W+RASS E+VLREAD+I
Sbjct: 181 ARMMVEGFKMNVIYYDLYQSTRLEKFVTAYGEFLKTQGEAPVHWRRASSPEDVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHL+NK+RLA+MKKEA+LVN SRGPVIDE ALVEHLK NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLINKDRLALMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGL D  NA+VVPHIASASKWTREGMATLAA NV  ++KGYP+W + N ++PFL
Sbjct: 301 DEPYMKPGLGDLPNAVVVPHIASASKWTREGMATLAAQNVAAKLKGYPVWPNSNNIEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLP 382
           +E+   P A+PSIVN+KALGLP
Sbjct: 361 DESKPAPAAAPSIVNAKALGLP 382
>gb|EAY84074.1| hypothetical protein OsI_005307 [Oryza sativa (indica
           cultivar-group)]
          Length = 399

 Score =  591 bits (1523), Expect = e-167,   Method: Composition-based stats.
 Identities = 303/399 (75%), Positives = 332/399 (83%), Gaps = 45/399 (11%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEV+NP+GKYRVVSTK MPGTRWI LL D  CR+E                   
Sbjct: 1   MAKPISIEVWNPSGKYRVVSTKSMPGTRWIRLLADNDCRLE------------------- 41

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTP---- 116
                    LTE+WGE LFSAL +AGG AFSNMAVGYNNVDVEAAN+ GIAVGNTP    
Sbjct: 42  ---------LTEEWGEVLFSALKRAGGTAFSNMAVGYNNVDVEAANRNGIAVGNTPVSSA 92

Query: 117 -------------GVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLL 163
                        GVLTETTAELAASLSLAAARRIVEAD+FMR GLY+GWLPHLFVGNLL
Sbjct: 93  ALCFLISRLSYWMGVLTETTAELAASLSLAAARRIVEADQFMRAGLYDGWLPHLFVGNLL 152

Query: 164 KGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 223
           KGQTVGVIGAGRIGSAYARMM+EGFKMNLIY+DLYQSTRLEKFVTAYGQFLKANGEQPVT
Sbjct: 153 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYYDLYQSTRLEKFVTAYGQFLKANGEQPVT 212

Query: 224 WKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALV 283
           WKRA++ME+VLREAD+ISLHPVLDKTTYHL+N ERLA+MKKEA+LVN SRGPVIDE ALV
Sbjct: 213 WKRAATMEDVLREADVISLHPVLDKTTYHLINPERLAIMKKEAVLVNASRGPVIDEVALV 272

Query: 284 EHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGR 343
           EHLK NPMFRVGLDVFE+EP+MKPGLAD KNA+VVPHIASASKWTREGMATLAALNVLG+
Sbjct: 273 EHLKANPMFRVGLDVFEDEPYMKPGLADMKNAVVVPHIASASKWTREGMATLAALNVLGK 332

Query: 344 VKGYPIWHDPNRVDPFLNENASPPNASPSIVNSKALGLP 382
           +KGYP+W +PN V+PFL E+A+PP A PSIVN+K LG P
Sbjct: 333 IKGYPVWGNPNLVEPFLKEDATPPAACPSIVNAKQLGRP 371
>gb|EAZ21390.1| hypothetical protein OsJ_004873 [Oryza sativa (japonica
           cultivar-group)]
          Length = 380

 Score =  590 bits (1522), Expect = e-167,   Method: Composition-based stats.
 Identities = 307/408 (75%), Positives = 336/408 (82%), Gaps = 50/408 (12%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEV+NP+GKYRVVSTK MPGTRWI LL D  CR+E                   
Sbjct: 1   MAKPISIEVWNPSGKYRVVSTKSMPGTRWIRLLADNDCRLE------------------- 41

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTP---- 116
                    LTE+WGE LFSAL +AGG AFSNMAVGYNNVDVEAAN+ GIAVGNTP    
Sbjct: 42  ---------LTEEWGEVLFSALKRAGGTAFSNMAVGYNNVDVEAANRNGIAVGNTPVSSA 92

Query: 117 -------------GVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLL 163
                        GVLTETTAELAASLSLAAARRIVEAD+FMR GLY+GWLPHLFVGNLL
Sbjct: 93  ALCFLISRLSYWMGVLTETTAELAASLSLAAARRIVEADQFMRAGLYDGWLPHLFVGNLL 152

Query: 164 KGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 223
           KGQTVGVIGAGRIGSAYARMM+EGFKMNLIY+DLYQSTRLEKFVTAYGQFLKANGEQPVT
Sbjct: 153 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYYDLYQSTRLEKFVTAYGQFLKANGEQPVT 212

Query: 224 WKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALV 283
           WKRA++ME+VLREAD+ISLHPVLDKTTYHL+N ERLA+MKKEA+LVN SRGPVIDE ALV
Sbjct: 213 WKRAATMEDVLREADVISLHPVLDKTTYHLINPERLAIMKKEAVLVNASRGPVIDEVALV 272

Query: 284 EHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASK-----WTREGMATLAAL 338
           EHLK NPMFRVGLDVFE+EP+MKPGLAD KNA+VVPHIASASK     WTREGMATLAAL
Sbjct: 273 EHLKANPMFRVGLDVFEDEPYMKPGLADMKNAVVVPHIASASKSPNHQWTREGMATLAAL 332

Query: 339 NVLGRVKGYPIWHDPNRVDPFLNENASPPNASPSIVNSKALGLPVSKL 386
           NVLG++KGYP+W +PN V+PFL E+A+PP A PSIVN+K LGLP SKL
Sbjct: 333 NVLGKIKGYPVWGNPNLVEPFLKEDATPPAACPSIVNAKQLGLPSSKL 380
>ref|XP_001752353.1| predicted protein [Physcomitrella patens subsp. patens]
 gb|EDQ83086.1| predicted protein [Physcomitrella patens subsp. patens]
          Length = 385

 Score =  571 bits (1471), Expect = e-161,   Method: Composition-based stats.
 Identities = 283/380 (74%), Positives = 335/380 (88%), Gaps = 1/380 (0%)

Query: 2   AKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGD 61
           AK ++++V+N  G  RV+STKPMPGT+WI  L   GCRVE+C   K ILS +DI+ LIG+
Sbjct: 3   AKQLAVQVHNAGGTLRVLSTKPMPGTQWIKTLTSVGCRVEVCTEPKVILSTDDIVSLIGN 62

Query: 62  KCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTE 121
           KCDGVIGQLTEDWG+TLF AL KAGG A+SNMAVGYNNVDV+AA ++GI+VGNTPGVLTE
Sbjct: 63  KCDGVIGQLTEDWGDTLFGALKKAGGHAYSNMAVGYNNVDVDAATRHGISVGNTPGVLTE 122

Query: 122 TTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYA 181
           TTAELAA+L+LAAARR+VEAD+FMR G YEGWLP LFVGNLLKGQTVG+IGAGRIG+AYA
Sbjct: 123 TTAELAAALTLAAARRVVEADDFMRAGKYEGWLPTLFVGNLLKGQTVGIIGAGRIGTAYA 182

Query: 182 RMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLIS 241
           RMMVEGFKMN+IY+DLYQ+TRLEKFV+AYGQFL++ GE PV W+RASS E+VL+EAD++S
Sbjct: 183 RMMVEGFKMNVIYYDLYQATRLEKFVSAYGQFLESQGETPVHWRRASSPEDVLKEADVVS 242

Query: 242 LHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEE 301
           LHPVLDKTTYHL+NKERLA+MKK+A+LVN SRGPV+DE ALVEHLK NPMFRVGLDVFE+
Sbjct: 243 LHPVLDKTTYHLINKERLALMKKDAVLVNASRGPVVDETALVEHLKANPMFRVGLDVFED 302

Query: 302 EPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
           EP+MKPGL +  NA+VVPHIASASKWTREGMATLAA NV  ++KG+P+W  PN V+PFL+
Sbjct: 303 EPYMKPGLGELSNAVVVPHIASASKWTREGMATLAAQNVAAKLKGWPVWSSPN-VEPFLD 361

Query: 362 ENASPPNASPSIVNSKALGL 381
           E    P A+PSI+N+KAL L
Sbjct: 362 EIKPAPKAAPSIINAKALCL 381
>gb|ABD97861.1| NADH-dependent hydroxypyruvate reductase [Pachysandra terminalis]
          Length = 303

 Score =  563 bits (1451), Expect = e-159,   Method: Composition-based stats.
 Identities = 269/303 (88%), Positives = 293/303 (96%)

Query: 84  KAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADE 143
           +AGG+AFSNMAVGYNNVDV AANKYG+AVGNTPGVLTETTAELAASLS++AARRIVEADE
Sbjct: 1   RAGGRAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLTETTAELAASLSVSAARRIVEADE 60

Query: 144 FMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRL 203
           FMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM+EGFKMNLIY+DLYQ+TRL
Sbjct: 61  FMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYYDLYQATRL 120

Query: 204 EKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMK 263
           EKFVTAYG+FLKANGE PVTWKRASSMEEVLREAD+ISLHP+LDKTTYHL+NKERL+MMK
Sbjct: 121 EKFVTAYGEFLKANGEPPVTWKRASSMEEVLREADVISLHPILDKTTYHLINKERLSMMK 180

Query: 264 KEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIAS 323
           KEAILVNCSRGPV+DE ALVEHLKENPMFRVGLDVFE+EP+MKPGLAD KNAIVVPHIAS
Sbjct: 181 KEAILVNCSRGPVVDEVALVEHLKENPMFRVGLDVFEDEPYMKPGLADMKNAIVVPHIAS 240

Query: 324 ASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASPPNASPSIVNSKALGLPV 383
           ASKWTREGMATLAALNVLG++KGYP+W DPNRV+PFLN+N+ PP ASPSIVN+KALGL  
Sbjct: 241 ASKWTREGMATLAALNVLGKIKGYPVWSDPNRVEPFLNKNSPPPAASPSIVNAKALGLTA 300

Query: 384 SKL 386
           SKL
Sbjct: 301 SKL 303
>gb|AAB00105.1| NADH-dependent hydroxypyruvate reductase
          Length = 271

 Score =  484 bits (1247), Expect = e-135,   Method: Composition-based stats.
 Identities = 243/271 (89%), Positives = 258/271 (95%)

Query: 34  VDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSNM 93
           ++Q CRVEIC  KKTILSVEDI+ LIGDKCDGVIGQLTEDWGE LFSALS+AG KAFSNM
Sbjct: 1   IEQDCRVEICTEKKTILSVEDIVALIGDKCDGVIGQLTEDWGEVLFSALSRAGRKAFSNM 60

Query: 94  AVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGW 153
           AVGYNNVDV AANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMR G Y+GW
Sbjct: 61  AVGYNNVDVNAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRAGRYDGW 120

Query: 154 LPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQF 213
           LP+LFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYG+F
Sbjct: 121 LPNLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEF 180

Query: 214 LKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSR 273
           LKANGE PVTW+RASSM+EVLREAD+ISLHPVLDKTT+HLVNKE L  MKK+AIL+NCSR
Sbjct: 181 LKANGEVPVTWRRASSMDEVLREADVISLHPVLDKTTFHLVNKESLKAMKKDAILINCSR 240

Query: 274 GPVIDEAALVEHLKENPMFRVGLDVFEEEPF 304
           GPVIDEAALVEHLKENPMFRVGLDVFE+EP+
Sbjct: 241 GPVIDEAALVEHLKENPMFRVGLDVFEDEPY 271
>ref|XP_001691480.1| hydroxypyruvate reductase [Chlamydomonas reinhardtii]
 gb|EDP05213.1| hydroxypyruvate reductase [Chlamydomonas reinhardtii]
          Length = 418

 Score =  445 bits (1144), Expect = e-123,   Method: Composition-based stats.
 Identities = 239/377 (63%), Positives = 288/377 (76%)

Query: 5   VSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCD 64
           V +EV+N  G  RVV TK +PG RW+  L++ GCRVE+      ILS   I  LIG KCD
Sbjct: 37  VPVEVHNEGGSKRVVVTKTLPGERWLQFLINAGCRVEVSQHPDIILSNATIKQLIGTKCD 96

Query: 65  GVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTA 124
           GVIGQLTEDWG  LF AL +AGGKA+SN AVGYNNV V+ A K GI VGNTPGVLTETTA
Sbjct: 97  GVIGQLTEDWGAELFEALKQAGGKAYSNYAVGYNNVKVDEATKRGIPVGNTPGVLTETTA 156

Query: 125 ELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 184
           ELAA+L+LAAARR+ EAD FMR G Y+GWLP+LFVG LL+ +TVG+IGAGRIG+AYARMM
Sbjct: 157 ELAAALTLAAARRVPEADVFMRAGKYKGWLPNLFVGQLLQNKTVGIIGAGRIGAAYARMM 216

Query: 185 VEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHP 244
           VEG KMNL+YFD Y + +LE+++  YG+ L+  GE PV  KR  ++EEVL+EAD++SLH 
Sbjct: 217 VEGHKMNLVYFDPYPNKQLEEYIRLYGELLRHRGEPPVACKRVETVEEVLKEADVVSLHC 276

Query: 245 VLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPF 304
            LD +T HL+N +RLA+MK  A+LVN +RGP IDEAALV HLK NP FR GLDVFE+EP 
Sbjct: 277 NLDASTRHLINSQRLALMKPTAVLVNAARGPCIDEAALVAHLKANPEFRCGLDVFEDEPA 336

Query: 305 MKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENA 364
           MKPGLAD  NA++VPHIASAS WTR GMATLAA NV G + GYP+W+  + +       A
Sbjct: 337 MKPGLADCANAVIVPHIASASLWTRSGMATLAAANVAGILSGYPVWNKQDILGFVDKPLA 396

Query: 365 SPPNASPSIVNSKALGL 381
           + P A+PSIVN+K L L
Sbjct: 397 AAPLAAPSIVNAKELKL 413
>gb|AAW29979.1| hydroxypyruvate reductase [Chlamydomonas reinhardtii]
          Length = 310

 Score =  393 bits (1009), Expect = e-107,   Method: Composition-based stats.
 Identities = 206/303 (67%), Positives = 243/303 (80%)

Query: 49  ILSVEDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKY 108
           ILS   I  LIG KCDGVIGQLTEDWG  LF AL +AGGKA+SN AVGYNNV V+ A K 
Sbjct: 4   ILSNATIKQLIGTKCDGVIGQLTEDWGAELFEALKQAGGKAYSNYAVGYNNVKVDEATKR 63

Query: 109 GIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTV 168
           GI VGNTPGVLTETTAELAA+L+LAAARR+ EAD FMR G Y+GWLP+LFVG LL+ +TV
Sbjct: 64  GIPVGNTPGVLTETTAELAAALTLAAARRVPEADVFMRAGKYKGWLPNLFVGQLLQNKTV 123

Query: 169 GVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRAS 228
           G+IGAGRIG+AYARMMVEG KMNL+YFD Y + +LE+++  YG+ L+  GE PV  KR  
Sbjct: 124 GIIGAGRIGAAYARMMVEGHKMNLVYFDPYPNKQLEEYIRLYGELLRHRGEPPVACKRVE 183

Query: 229 SMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKE 288
           ++EEVL+EAD++SLH  LD +T HL+N +RLA+MK  A+LVN +RGP IDEAALV HLK 
Sbjct: 184 TVEEVLKEADVVSLHCNLDASTRHLINSQRLALMKPTAVLVNAARGPCIDEAALVAHLKA 243

Query: 289 NPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYP 348
           NP FR GLDVFE+EP MKPGLAD  NA++VPHIASAS WTR GMA LA  NV G + GYP
Sbjct: 244 NPEFRCGLDVFEDEPAMKPGLADCANAVIVPHIASASLWTRSGMAPLAPANVAGILSGYP 303

Query: 349 IWH 351
           +W+
Sbjct: 304 VWN 306
>gb|ABK55681.1| NAPH-dependent hydroxypyruvate reductase [Cucumis sativus]
          Length = 180

 Score =  342 bits (878), Expect = 2e-92,   Method: Composition-based stats.
 Identities = 156/180 (86%), Positives = 174/180 (96%)

Query: 182 RMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLIS 241
           RMMVEGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREAD+IS
Sbjct: 1   RMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEAPVTWRRASSMDEVLREADVIS 60

Query: 242 LHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEE 301
           LHPVLDKTT+HLVNKE L  MKK+AIL+NCSRGPVIDEAALV+HL++NPMFRVGLDVFE+
Sbjct: 61  LHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDNPMFRVGLDVFED 120

Query: 302 EPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
           EP+MKPGLAD KNAI+VPHIASASKWTREGMATLAALNVLG++KGYP+W DPNRV+PFL+
Sbjct: 121 EPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPVWSDPNRVEPFLD 180
>ref|YP_430795.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Moorella thermoacetica ATCC 39073]
 gb|ABC20252.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Moorella thermoacetica ATCC 39073]
          Length = 329

 Score =  252 bits (644), Expect = 3e-65,   Method: Composition-based stats.
 Identities = 145/332 (43%), Positives = 214/332 (64%), Gaps = 23/332 (6%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K+ V  T+ +P    ++LL +  C +EI + +  +L+  ++++ +  + DG++  LT+  
Sbjct: 3   KWNVYVTRLVPQPA-LDLLAEY-CDLEI-NPEDRVLTRAELLEKVRGR-DGILCLLTDIL 58

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
            + +F+A    G K F+N+AVG+NNVD+EAA ++GI + NTPGVLTE TA++A +L  A 
Sbjct: 59  DDEVFTA--AKGAKIFANLAVGFNNVDLEAATRHGIMITNTPGVLTEATADMAWALLFAV 116

Query: 135 ARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIY 194
           ARR+VE D+F R G Y+GW P L +G  + G+T+GVIGAGRIG+A+AR    GF M ++Y
Sbjct: 117 ARRVVEGDKFTRAGKYKGWGPLLMLGQEITGKTLGVIGAGRIGTAFAR-KARGFDMKVLY 175

Query: 195 FDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
            D+  S   E+     GQF+                E +L+EAD +SLH  L  +T HL+
Sbjct: 176 HDVQPSKAFEE--ATGGQFVDK--------------ETLLKEADFVSLHVPLMPSTTHLI 219

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKN 314
           +   L +MKK AIL+N SRGPV+DE ALV+ L+E  ++  GLDVFE EP + PGLAD +N
Sbjct: 220 STPELKLMKKTAILINTSRGPVVDEKALVKALREKEIWGAGLDVFENEPELAPGLADLEN 279

Query: 315 AIVVPHIASASKWTREGMATLAALNVLGRVKG 346
            ++ PHIASA+  TR  MA +AA N+L  ++G
Sbjct: 280 VVLCPHIASATWETRTNMALMAANNLLAALRG 311
>ref|YP_001410651.1| Glyoxylate reductase [Fervidobacterium nodosum Rt17-B1]
 gb|ABS60994.1| Glyoxylate reductase [Fervidobacterium nodosum Rt17-B1]
          Length = 317

 Score =  241 bits (614), Expect = 9e-62,   Method: Composition-based stats.
 Identities = 146/332 (43%), Positives = 203/332 (61%), Gaps = 26/332 (7%)

Query: 17  RVVSTKPMPGTRWINLLVDQGCRVEI-CHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWG 75
           RV  T  +P  + IN+L +   R E+  +  +  LS E++I    +  D ++ QL +   
Sbjct: 2   RVFVTYAIP-EKGINMLKE---RFEVDVYTGEEFLSKEEMIKR-AEYADAIVTQLRDPID 56

Query: 76  ETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAA 135
           +    +L KA  K  +N AVGYNN+D+EAA + GI V NTPGVLTE TA++A +L LA A
Sbjct: 57  KEFIYSLKKA--KIIANYAVGYNNIDIEAAKERGIYVTNTPGVLTEATADIAFALILAVA 114

Query: 136 RRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYF 195
           RRIVE+D+F+R G + GW P LF+G  L G+T+GVIG GRIG A AR  + GF MN++Y 
Sbjct: 115 RRIVESDKFVREGKFVGWKPKLFLGYDLYGKTLGVIGMGRIGQAVARRAL-GFGMNIVY- 172

Query: 196 DLYQSTRL-EKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
             Y   RL E+    Y               +  +++E++  +D ISLH  L K TYHL+
Sbjct: 173 --YNRNRLPEEIEKQYN-------------AKYVNIDELVEISDYISLHTPLTKETYHLI 217

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKN 314
           NKER+A MK  AILVN +RGPV+DE AL E LKE  +   G DV+E EP + PGL    N
Sbjct: 218 NKERIAKMKPNAILVNTARGPVVDEQALYEALKERRIAGAGFDVYENEPVLTPGLEKLDN 277

Query: 315 AIVVPHIASASKWTREGMATLAALNVLGRVKG 346
            +++PHI SA+  TR+ M+ + A+NV+  + G
Sbjct: 278 VVLLPHIGSATYETRDKMSEIVAINVMEALDG 309
>gb|ACB69759.1| hydroxypyruvate reductase [Solanum lycopersicum]
          Length = 116

 Score =  237 bits (604), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 110/116 (94%), Positives = 114/116 (98%)

Query: 136 RRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYF 195
           RRIVEADEFMR G YEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIY+
Sbjct: 1   RRIVEADEFMRAGKYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYY 60

Query: 196 DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVL+EAD+ISLHP+LDKTTY
Sbjct: 61  DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLQEADVISLHPILDKTTY 116
>ref|YP_001179183.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Caldicellulosiruptor saccharolyticus DSM 8903]
 gb|ABP65992.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Caldicellulosiruptor saccharolyticus DSM 8903]
          Length = 323

 Score =  229 bits (584), Expect = 3e-58,   Method: Composition-based stats.
 Identities = 132/297 (44%), Positives = 192/297 (64%), Gaps = 20/297 (6%)

Query: 50  LSVEDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYG 109
           ++ E ++  I DK D V+ QL +   +  F        K  +N AVGY+N+D+E A K G
Sbjct: 32  MTREQLLKAIADK-DAVLTQLVDKVDKEFFDHAPNV--KIVANYAVGYDNIDIEEATKRG 88

Query: 110 IAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVG 169
           + V NTP VLT  TAELA +L  AAARRIVEAD+FMRGG Y+GW P LF+G  + G+T+G
Sbjct: 89  VYVTNTPDVLTNATAELAWALLFAAARRIVEADKFMRGGHYKGWGPMLFLGKGITGKTLG 148

Query: 170 VIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASS 229
           VIGAGRIG A+ARM  +GF M ++Y+D  +    E+ + A  Q++              +
Sbjct: 149 VIGAGRIGQAFARMS-KGFNMKILYYDFERKENFEEEMGA--QYV--------------A 191

Query: 230 MEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKEN 289
           ++E+L+EAD IS+H  L   T H++ +  L++MK  AIL+N +RGP++DE ALV+ LKE 
Sbjct: 192 LDELLKEADFISIHVPLTPQTRHMIGERELSLMKPSAILINTARGPIVDEKALVKALKEK 251

Query: 290 PMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKG 346
            ++  GLDV+E EP  +P LA+  N +++PHI SA++ +R  MA LAA N++  ++G
Sbjct: 252 KIYAAGLDVYEREPEFEPELAELDNVVMLPHIGSATEESRLDMAMLAANNIVDFIEG 308
>ref|YP_001471315.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Thermotoga lettingae TMO]
 gb|ABV34251.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Thermotoga lettingae TMO]
          Length = 327

 Score =  222 bits (565), Expect = 5e-56,   Method: Composition-based stats.
 Identities = 135/318 (42%), Positives = 193/318 (60%), Gaps = 24/318 (7%)

Query: 35  DQGCRVEICHLKKTILSVEDII--DLIGDKCDGVIGQLTEDWGETLFSALSKAGGK---A 89
           D+G ++   H +  I + + ++  D++ DK  GV G L     + +   + +A GK    
Sbjct: 14  DEGLKMISQHCEMQIGNYDGVLPKDVLIDKVKGVDGILCL-LADVIDKDVMEAAGKQLKV 72

Query: 90  FSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGL 149
            +N AVGYNN+D+E A K GI V NTPGVLTETTA+LA +L ++ ARRIVE+D+F+R G 
Sbjct: 73  IANYAVGYNNIDIEEATKRGIMVTNTPGVLTETTADLAWALMMSIARRIVESDKFVREGK 132

Query: 150 YEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTR-LEKFVT 208
           + GW P L +G  + G T+GV+G GRIG A AR    GF M ++Y+   ++   +EK + 
Sbjct: 133 FNGWQPMLMLGTDIYGATLGVVGFGRIGQAVAR-RASGFNMRVLYYSRKRAPEDVEKQLN 191

Query: 209 AYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAIL 268
           A   F+               +  +LRE+D ++LH  L K TYHL+ +E L MMKKEA L
Sbjct: 192 A--SFV--------------DLSTLLRESDFVTLHLPLTKETYHLIGEEELRMMKKEAYL 235

Query: 269 VNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWT 328
           +N +RGPVIDE ALV+ LK   +    LDVFE+EP ++P L +  N I+ PHI SAS  T
Sbjct: 236 INTARGPVIDEKALVKALKNKWIRGAALDVFEKEPQIEPELLELDNVILTPHIGSASYTT 295

Query: 329 REGMATLAALNVLGRVKG 346
           R  M+ +AA N++  + G
Sbjct: 296 RTKMSVMAAENLVKALYG 313
>ref|ZP_01666395.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermosinus carboxydivorans Nor1]
 gb|EAX47745.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermosinus carboxydivorans Nor1]
          Length = 327

 Score =  222 bits (565), Expect = 5e-56,   Method: Composition-based stats.
 Identities = 134/345 (38%), Positives = 201/345 (58%), Gaps = 25/345 (7%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
            ++ V  T+ +P T  +++L  Q C VE+ + +  +L+ ++++  +  + D V+  LT+ 
Sbjct: 2   AQFNVYVTRRIPDTA-LDVL-RQRCNVEV-NPEDRVLTRDELLAKVTGR-DAVLCLLTDT 57

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
             + + +A  K   + F+N AVGYNN+DV AA K GI + NTP VLT  TA++A +L  A
Sbjct: 58  IDDAVLAAAGKQC-RIFANYAVGYNNIDVAAATKRGIFISNTPDVLTAATADMAWALLFA 116

Query: 134 AARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
            ARR+VE D+F R G + GW P L +G  + G+TVG+IGAGRIG+A+AR   +GF M ++
Sbjct: 117 VARRVVEGDKFTRAGKFHGWGPLLMLGQEVTGKTVGIIGAGRIGAAFAR-RAKGFDMKIL 175

Query: 194 YFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHL 253
           Y    +    E+             E   T+      + +LREAD ISLH  L   TYHL
Sbjct: 176 YTGRSRKPDFER-------------ETGATY---VDFDTLLREADFISLHVPLTPETYHL 219

Query: 254 VNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTK 313
           + +  L +MK  AIL+N +RGPV+DE ALV  L+   ++  GLDVFE EP +  GLA+  
Sbjct: 220 IGERELKLMKPTAILINTARGPVVDEKALVAALRRGEIWGAGLDVFENEPALAEGLAELD 279

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDP 358
           N ++ PH+ SA+  TR  M  +A  N+L  + G      PN ++P
Sbjct: 280 NVVIPPHLGSATLETRTKMGLVAVENILAALDGR---MPPNCLNP 321
>ref|ZP_01187992.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Halothermothrix orenii H 168]
 gb|EAR80319.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Halothermothrix orenii H 168]
          Length = 274

 Score =  220 bits (560), Expect = 2e-55,   Method: Composition-based stats.
 Identities = 122/276 (44%), Positives = 178/276 (64%), Gaps = 19/276 (6%)

Query: 88  KAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRG 147
           K  +N AVGYNN+DVEAA + G+AV NTPGVLTE TA+L  +L +A ARRI+E+D+F+R 
Sbjct: 18  KVVANYAVGYNNIDVEAATRQGVAVTNTPGVLTEATADLTWALLMAVARRIIESDQFVRQ 77

Query: 148 GLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFV 207
           G ++GW P L +G+ + G+T+G+IG GRIG A AR    GF M ++Y    + TRL +  
Sbjct: 78  GQFKGWGPRLMLGSDVYGKTLGIIGFGRIGQAVAR-RARGFNMEILY---NKRTRLSR-- 131

Query: 208 TAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAI 267
                    + E+ +  + A  ++E+L+ AD IS++  L+K+TYHLV  +   +MK  AI
Sbjct: 132 ---------DREEKLGVQYA-EVDELLKRADYISINAPLNKSTYHLVGLQEFELMKNTAI 181

Query: 268 LVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKW 327
           ++N  RGP+IDE+ALVE LKE  +   GLDV+EEEP + PGL +  N ++ PH  S +  
Sbjct: 182 VINTGRGPIIDESALVEALKEGKIAGAGLDVYEEEPEVHPGLMELDNVVLTPHTGSGTIE 241

Query: 328 TREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNEN 363
           TR+ MA + A +V+  +KG       N V+P + +N
Sbjct: 242 TRDKMAVMVAEDVIAVLKGK---RPANLVNPGVYKN 274
>ref|NP_623521.1| glyoxylate reductase [Thermoanaerobacter tengcongensis MB4]
 gb|AAM25125.1| Lactate dehydrogenase and related dehydrogenases
           [Thermoanaerobacter tengcongensis MB4]
          Length = 324

 Score =  219 bits (558), Expect = 3e-55,   Method: Composition-based stats.
 Identities = 132/314 (42%), Positives = 197/314 (62%), Gaps = 21/314 (6%)

Query: 33  LVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSN 92
           L+ + C VE+    + +L+ E++++ I DK D VI QLT+   +  F A      K  +N
Sbjct: 17  LLRKYCEVEVSPYDR-MLTKEELLEKIKDK-DAVITQLTDKVDKEFFEAAKNV--KIVAN 72

Query: 93  MAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYEG 152
            AVG++N+D+E A K G+ + NTP VLT  TAELA +L  AAARR+VEAD+FMR G ++G
Sbjct: 73  YAVGFDNIDLEEATKRGVYITNTPDVLTNATAELAWALLFAAARRVVEADKFMRAGKFQG 132

Query: 153 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQ 212
           W P LF+G  + G+T+GVIGAGRIG A+A+ M +GF+M ++Y     + R  K      +
Sbjct: 133 WAPMLFLGKGVTGKTLGVIGAGRIGQAFAK-MAKGFEMKILY-----NARTPK-----PE 181

Query: 213 FLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCS 272
           F K  G + V       ++ +L+E+D +S+H  L   T HL+ +  L +MK  AIL+N  
Sbjct: 182 FEKETGAKYV------DLDTLLKESDFVSIHLPLTPETRHLIGERELKLMKNSAILINTG 235

Query: 273 RGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGM 332
           RGPV+DE ALV+ LKE  ++  GLDV+E EP  +  LA+  N +++PHI SA++  R  M
Sbjct: 236 RGPVVDEKALVKALKEKWIYAAGLDVYEREPEFEKELAELDNVVMLPHIGSATEEARRDM 295

Query: 333 ATLAALNVLGRVKG 346
           + L A N++  ++G
Sbjct: 296 SVLVAQNIIDVIEG 309
>emb|CAO81265.1| glyoxylate reductase (glycolate:NAD+ oxidoreductase) [Candidatus
           Cloacamonas acidaminovorans]
          Length = 317

 Score =  215 bits (548), Expect = 4e-54,   Method: Composition-based stats.
 Identities = 125/297 (42%), Positives = 182/297 (61%), Gaps = 21/297 (7%)

Query: 50  LSVEDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYG 109
           L+ +++I+ + D  + +I  LT++  + + SA  K   K  S+ AVGYNN++VE A + G
Sbjct: 34  LTHQELIEGVKD-AEALICLLTDNIDKEVISAAPKL--KVISSYAVGYNNIEVEYATQLG 90

Query: 110 IAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVG 169
           IAV NTPGVLTETTA+L  +L LA  RRI E++ F+R G ++GW P L +G  + G+T+G
Sbjct: 91  IAVCNTPGVLTETTADLTWALILATCRRISESERFLRKGNFKGWEPMLMLGLDVYGKTLG 150

Query: 170 VIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASS 229
           +IG GRIG A A+    GF M +IY++    +    F T                   + 
Sbjct: 151 IIGMGRIGQAVAKRAT-GFAMRIIYYNDVSVSNTLPFETT-----------------ETD 192

Query: 230 MEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKEN 289
           ++ +L+EAD+I+LH  L K T+HL+ KE  A+MK+ A+L+N SRG VIDE  L++ L E 
Sbjct: 193 LQTLLKEADIITLHLPLTKETFHLIGKEEFALMKENAVLINTSRGAVIDEKELIKALSEK 252

Query: 290 PMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKG 346
            +F  GLDV+E EP +   L   +N +++PHI SAS  TR  MA LAA N +  +KG
Sbjct: 253 RIFSAGLDVYENEPDIPQELLALENVVLLPHIGSASIETRTKMALLAAENAIAVMKG 309
>ref|YP_001568546.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Petrotoga mobilis SJ95]
 gb|ABX32223.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Petrotoga mobilis SJ95]
          Length = 320

 Score =  213 bits (541), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 122/302 (40%), Positives = 182/302 (60%), Gaps = 20/302 (6%)

Query: 46  KKTILSVEDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAA 105
           K  +L+ E++ + I  + D +I  L +     +  A  K   K  +N AVGYNN+D++ A
Sbjct: 29  KDKLLTKEELKE-IAKESDALITMLADPIDSEVLEA-GKDRLKIVANYAVGYNNIDIQKA 86

Query: 106 NKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKG 165
            + GI V NTP VLTETTA+LA +L L  ARRIVE+D F R G ++GW P LF+G  + G
Sbjct: 87  KELGIYVTNTPDVLTETTADLAWALMLVVARRIVESDAFTREGKFDGWKPELFLGTDVYG 146

Query: 166 QTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQ-STRLEKFVTAYGQFLKANGEQPVTW 224
           +T+G+IG G IG A AR  + GF M + Y+  ++ S+  EK + A   +L          
Sbjct: 147 KTLGIIGFGSIGQAVARRAI-GFNMKVYYYQRHRLSSEKEKALNA--TYL---------- 193

Query: 225 KRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVE 284
               +++E+L+ +D +SLH  L   TYH++++E+L+++KK A ++N +RGPVIDE AL E
Sbjct: 194 ----NLDELLKVSDYVSLHVPLTDETYHMLDREKLSLLKKSAFVINTARGPVIDEEALYE 249

Query: 285 HLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRV 344
            LK   +    LDV+E EP + P L D  N ++ PHI SAS  TR  MA + A +++  +
Sbjct: 250 KLKSKEISGAALDVYENEPQLTPDLKDLDNVVLTPHIGSASHETRSRMAQMVAKDIIQAL 309

Query: 345 KG 346
            G
Sbjct: 310 DG 311
>ref|YP_001662713.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermoanaerobacter sp. X514]
 gb|ABY92377.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermoanaerobacter sp. X514]
          Length = 323

 Score =  211 bits (537), Expect = 8e-53,   Method: Composition-based stats.
 Identities = 133/314 (42%), Positives = 189/314 (60%), Gaps = 21/314 (6%)

Query: 33  LVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSN 92
           L+ + C VEI + +   L  E+++D+I DK D V+ QL E      F   S    K  +N
Sbjct: 17  LLKKYCEVEI-NPEDRPLKREELLDVIKDK-DAVVTQLNEKVDAEFFD--SAKNLKIVAN 72

Query: 93  MAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYEG 152
            AVG++N+D++ A K  I V NTP VLT  TAELA +L  AAARR+VEAD+F R G + G
Sbjct: 73  YAVGFDNIDLKEATKRKIYVTNTPDVLTNATAELAWALLFAAARRVVEADKFTREGKFTG 132

Query: 153 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQ 212
           W P+LF+G  + G+T+GVIGAGRIG A+A+M  +GF M ++Y             T   +
Sbjct: 133 WAPNLFLGKAVTGKTLGVIGAGRIGQAFAKMS-KGFDMKILY----------TANTPKEE 181

Query: 213 FLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCS 272
           F K  G + V       +E +L+E+D +SLH  L   T HL+ ++ L +MKK AIL+N +
Sbjct: 182 FEKETGAKYV------DLETLLKESDFVSLHVPLTPHTRHLIGEKELKLMKKTAILINTA 235

Query: 273 RGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGM 332
           RGPV+DE ALV  LK   ++  GLDV+E+EP +   L    N +++PHI SA+   R  M
Sbjct: 236 RGPVVDEKALVNALKNKDIYAAGLDVYEKEPEITEELKTLDNVVILPHIGSATDEARRDM 295

Query: 333 ATLAALNVLGRVKG 346
           A L A N++  ++G
Sbjct: 296 AVLVAQNIIDVIEG 309
>ref|YP_001664595.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermoanaerobacter pseudethanolicus ATCC 33223]
 gb|ABY94259.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermoanaerobacter pseudethanolicus ATCC 33223]
          Length = 323

 Score =  210 bits (535), Expect = 1e-52,   Method: Composition-based stats.
 Identities = 132/314 (42%), Positives = 189/314 (60%), Gaps = 21/314 (6%)

Query: 33  LVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSN 92
           L+ + C VEI + +   L  E+++D+I DK D V+ QL E      F   S    K  +N
Sbjct: 17  LLKKYCEVEI-NPEDRPLKREELLDVIKDK-DAVVTQLNEKVDAEFFD--SAKNLKIVAN 72

Query: 93  MAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYEG 152
            AVG++N+D++ A K  I V NTP VLT  TAELA +L  AAARR++EAD+F R G + G
Sbjct: 73  YAVGFDNIDLKEATKRKIYVTNTPDVLTNATAELAWALLFAAARRVIEADKFTREGKFTG 132

Query: 153 WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQ 212
           W P+LF+G  + G+T+GVIGAGRIG A+A+M  +GF M ++Y             T   +
Sbjct: 133 WAPNLFLGKAVTGKTLGVIGAGRIGQAFAKMS-KGFDMKILY----------TANTPKEE 181

Query: 213 FLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCS 272
           F K  G + V       +E +L+E+D +SLH  L   T HL+ ++ L +MKK AIL+N +
Sbjct: 182 FEKETGAKYV------DLETLLKESDFVSLHVPLTPHTRHLIGEKELKLMKKTAILINTA 235

Query: 273 RGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGM 332
           RGPV+DE ALV  LK   ++  GLDV+E+EP +   L    N +++PHI SA+   R  M
Sbjct: 236 RGPVVDEKALVNALKNKDIYAAGLDVYEKEPEITEELKALDNVVILPHIGSATDEARRDM 295

Query: 333 ATLAALNVLGRVKG 346
           A L A N++  ++G
Sbjct: 296 AVLVAQNIIDVIEG 309
>ref|ZP_03856830.1| lactate dehydrogenase-like oxidoreductase [Thermobaculum terrenum
           ATCC BAA-798]
 gb|EEI02352.1| lactate dehydrogenase-like oxidoreductase [Thermobaculum terrenum
           ATCC BAA-798]
          Length = 319

 Score =  202 bits (514), Expect = 4e-50,   Method: Composition-based stats.
 Identities = 134/352 (38%), Positives = 193/352 (54%), Gaps = 48/352 (13%)

Query: 16  YRVVSTKPMPGTRWINLLVDQGCRVEIC---------HLKKTILSVEDIIDLIGDKCDGV 66
           YRV  T+ +P    + LL D G  ++I           LK+ I   + +I L+ DK D  
Sbjct: 2   YRVYITRKIPEAG-LRLLKDHGFELDIWPGDLPPSKEELKRGISQADAMISLLTDKID-- 58

Query: 67  IGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAEL 126
                    E + S       K  +N AVGY+N+D+EAA K GI V NTP VLTETTA+L
Sbjct: 59  ---------EEVISNARNL--KVIANYAVGYDNIDLEAATKAGIVVTNTPDVLTETTADL 107

Query: 127 AASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVE 186
           A +L L+ ARR++E    ++ G +  W P L +G  + G T+G++G GRIG A AR  + 
Sbjct: 108 AWALMLSVARRLIEGVSHVKDGKWRTWEPQLLLGQDVYGATLGIVGMGRIGQAVARRAI- 166

Query: 187 GFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVL 246
           GF+M ++Y    + T ++                     +  S++E+L ++D ISLH  L
Sbjct: 167 GFQMKVLYTSRSEKTGID--------------------AQKVSLDELLAQSDFISLHTPL 206

Query: 247 DKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMK 306
            K T H++NK  L  MK  AIL+N +RGP++D AALVE L+E  +   GLDV + EP  +
Sbjct: 207 TKETRHMINKSTLKRMKPTAILINTARGPLVDTAALVEALREGQIAGAGLDVTDPEPLPR 266

Query: 307 PG-LADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVD 357
              L    N IVVPHI SAS+ TR+ M+ +AA NV+  ++G      PN+V+
Sbjct: 267 NHPLLYLPNCIVVPHIGSASQRTRDLMSEIAARNVIAVLEGS---QAPNQVN 315
>ref|ZP_02943614.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Micrococcus luteus NCTC 2665]
 gb|EDT58468.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Micrococcus luteus NCTC 2665]
          Length = 329

 Score =  201 bits (510), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 119/277 (42%), Positives = 167/277 (60%), Gaps = 13/277 (4%)

Query: 82  LSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEA 141
           L+ A  +  +N AVGYNNVDV AA + GIAVGNTP VLT+ TA++A  L L   RR  E 
Sbjct: 62  LADARIRGIANYAVGYNNVDVAAATRRGIAVGNTPDVLTDATADIAMLLILGVTRRAHEG 121

Query: 142 DEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQST 201
           +  +R G + GW P L VG  ++G T+G+ G GRIG A A   +  F M++++     + 
Sbjct: 122 ERMVREGRFHGWAPDLLVGRDVRGATLGLAGFGRIGKAVAERAL-AFGMDVVFAPRPPAH 180

Query: 202 RLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAM 261
           R E      G    A   + V W      EE++  AD++SLH  L   T+HLV+ E +A 
Sbjct: 181 R-EVAAEELGDL--AGRVRQVRW------EELVEVADVLSLHVPLTDDTHHLVDAEVIAK 231

Query: 262 MKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHI 321
           MK +A+LVN +RGPV+DE ALV  L+E  +F  GLDV+E+EP + PGLA+ +N +++PH+
Sbjct: 232 MKDDAVLVNTARGPVVDEVALVTALREGRLFGAGLDVYEDEPALAPGLAELENVMLLPHL 291

Query: 322 ASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDP 358
            SA++ TR  MA LAA N +    G  +   P  V+P
Sbjct: 292 GSATRDTRAAMAELAARNAIAMATGAEV---PALVNP 325
>ref|YP_001306138.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermosipho melanesiensis BI429]
 gb|ABR30753.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermosipho melanesiensis BI429]
          Length = 318

 Score =  200 bits (509), Expect = 1e-49,   Method: Composition-based stats.
 Identities = 121/283 (42%), Positives = 173/283 (61%), Gaps = 20/283 (7%)

Query: 64  DGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETT 123
           D VI QL +        A      K  +N AVGYNN+DVE A K GI V NTP VLTE T
Sbjct: 45  DAVITQLRDPVDREFIDAGKNL--KIIANYAVGYNNIDVEYAKKKGIYVTNTPDVLTEAT 102

Query: 124 AELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARM 183
           A++A +L LA AR+I+ AD+F+R G +EGW PHLF+G+ + G+T+G+IG GRIG A AR 
Sbjct: 103 ADIAWALILAVARKIIPADKFVREGKFEGWKPHLFLGHEIYGKTIGIIGMGRIGKAVARR 162

Query: 184 MVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLH 243
            + GF M ++Y +  +     K+   Y +                 +E +L+E+D IS+H
Sbjct: 163 AM-GFGMKILYHNRKKVDDDYKYNAKYVE-----------------LETLLKESDYISIH 204

Query: 244 PVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEP 303
             L K TYHL++ E+L+++K  +IL+N +RGPV+DE AL E L+E  +   G DV+E EP
Sbjct: 205 TPLTKETYHLLDSEKLSLLKPTSILINTARGPVVDEKALYEFLREGKIAGAGFDVYENEP 264

Query: 304 FMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKG 346
            +  GL    N +++PHI SA+  TRE M+ + A NV+  ++G
Sbjct: 265 KLTSGLEKLDNVVLLPHIGSATYETREKMSIMVAENVIDALEG 307
>ref|ZP_02129818.1| Glyoxylate reductase [Desulfatibacillum alkenivorans AK-01]
 gb|EDQ28264.1| Glyoxylate reductase [Desulfatibacillum alkenivorans AK-01]
          Length = 326

 Score =  197 bits (501), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 119/315 (37%), Positives = 177/315 (56%), Gaps = 23/315 (7%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K++V  T+ +P    I LL  Q C V++    +  L+ +++ + I D  DGVIG L+E  
Sbjct: 3   KHKVYVTRAIP-KEGIELL-SQTCEVQVNPHDRP-LTQDELFEAIAD-ADGVIGLLSERI 58

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
             T F+A  K   K ++N AVG++N+DVE A + G+ V NTP VLT  TAE+A +L  + 
Sbjct: 59  DGTFFNAAPKL--KGYANYAVGFDNIDVEEATRRGVPVSNTPDVLTIATAEMAWALLFSV 116

Query: 135 ARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIY 194
            R I  +D+ +R   ++GW P  F+G  + G+T+G++GAGRIG A A+M  +GF M ++Y
Sbjct: 117 CRHIPASDKLVRNDSWKGWSPLQFIGAEVTGKTLGIVGAGRIGRAMAQMS-KGFNMKVLY 175

Query: 195 FDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
           F        E+ + A                    +EE+L ++D ISLH  L   T H+ 
Sbjct: 176 FSRTNKPDFEEALNA----------------EKVELEELLIQSDFISLHTPLTPETRHMF 219

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKN 314
           N E    MK  A L+N +RGPV+DE+AL+E LK   +   GLDV+E EP + PGL +  N
Sbjct: 220 NAESFKKMKNTAYLINTARGPVVDESALIEALKSGEIAGAGLDVYEFEPKLTPGLRELDN 279

Query: 315 AIVVPHIASASKWTR 329
            ++  H  SA+   R
Sbjct: 280 VVLAAHTGSATDTAR 294
>ref|YP_848018.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Syntrophobacter fumaroxidans MPOB]
 gb|ABK19583.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Syntrophobacter fumaroxidans MPOB]
          Length = 327

 Score =  197 bits (500), Expect = 1e-48,   Method: Composition-based stats.
 Identities = 114/268 (42%), Positives = 165/268 (61%), Gaps = 17/268 (6%)

Query: 79  FSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRI 138
           F AL+  G K  +N  VG++++D+ AA++ GI V  TPGVLT+ TA++A +L LA +RR+
Sbjct: 59  FLALA-PGLKIIANFGVGFDHIDIAAASRRGIPVTYTPGVLTDATADIAFALILAVSRRV 117

Query: 139 VEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLY 198
           VE D   R G +  W P  F+G  + G+T+G++G GRIG A AR    GF M ++Y   +
Sbjct: 118 VEGDRMTREGGFRFWAPFHFLGRQVSGKTLGIVGMGRIGEAVARR-AAGFDMKIVY---H 173

Query: 199 QSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKER 258
              RL+    A  Q L+A         R   + E+LREAD +SLH  L   T HL+  E 
Sbjct: 174 GRNRLDP---ADEQRLRA---------RYLPLHELLREADFVSLHVPLTTETRHLIGLEE 221

Query: 259 LAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVV 318
           L +MK  A+L+N SRGPV++EAALVE L+E  +   GLDV+E EP +  GL+  +N +++
Sbjct: 222 LRLMKPSAVLINTSRGPVVNEAALVEALQEGRIGGAGLDVYENEPELAAGLSGLENVVLL 281

Query: 319 PHIASASKWTREGMATLAALNVLGRVKG 346
           PH+ SA+  TR  MA +A  N+L  ++G
Sbjct: 282 PHVGSATIETRTKMALMAVENLLVGLRG 309
>emb|CAM32608.1| Dehydrogenase oxidoreductase protein [Herbaspirillum seropedicae]
          Length = 326

 Score =  196 bits (498), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 122/295 (41%), Positives = 168/295 (56%), Gaps = 20/295 (6%)

Query: 64  DGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETT 123
           DG+    +E     LF+A  +   KA  NMAVGYNN+DV AA + G+   NTP VL ETT
Sbjct: 47  DGLFTTPSEPVTAALFAANPQL--KAVCNMAVGYNNIDVAAATQAGVMATNTPDVLNETT 104

Query: 124 AELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARM 183
           A+   +L +AAARRI E++ F+R G ++ W    FVG  + G T+G+IG GRIG A AR 
Sbjct: 105 ADFGWALMMAAARRITESEHFLRAGKWKKWSYDSFVGPDIHGATLGIIGMGRIGQAIARR 164

Query: 184 MVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLH 243
            + GF M ++Y   +  +RL   + A     +AN        R  S EE+LR+AD + L 
Sbjct: 165 SL-GFDMQVLY---HNRSRLAPELEA-----RANH------ARYVSKEELLRQADHVILV 209

Query: 244 PVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEP 303
               K T+H +    LA+MK  A L N +RG ++D+AAL+  L+E  +   G+DVFE EP
Sbjct: 210 LPYSKDTHHTIAAAELALMKPTATLTNIARGGIVDDAALIAALREGRIAAAGVDVFENEP 269

Query: 304 FMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDP 358
             KP   D  N ++ PHIASAS  TR  MA  AA N++  + G      PN ++P
Sbjct: 270 AFKPEFLDLSNVVLTPHIASASTPTRLAMANCAADNLIAALSGQ---RPPNLLNP 321
>ref|ZP_02836463.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Arthrobacter chlorophenolicus A6]
 gb|EDS63701.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Arthrobacter chlorophenolicus A6]
          Length = 329

 Score =  196 bits (498), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 125/290 (43%), Positives = 174/290 (60%), Gaps = 17/290 (5%)

Query: 64  DGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETT 123
           D V+ QL +     L   L+ A  K  SN AVGYNN+D++AA ++GI VGNTPGVLT+ T
Sbjct: 47  DAVLTQLRDVVDAPL---LAGARVKGISNYAVGYNNIDIDAATRHGILVGNTPGVLTDAT 103

Query: 124 AELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARM 183
           A++A  L L AARR+VEAD  +R G + GW P L +G  + G  +GV G GRI  A AR 
Sbjct: 104 ADIAMLLILGAARRVVEADRLVRDGKFHGWEPELLLGRDVSGAVLGVAGFGRIARATARR 163

Query: 184 MVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLH 243
            + GF M +I+       R        G+F  A   Q V W       E++  +D +SLH
Sbjct: 164 AL-GFGMQVIFSPRPPGDRPVS-EDELGEF--AGKVQQVAW------SELIERSDFLSLH 213

Query: 244 PVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEP 303
             L++ T HLV+ + L  MK +AIL+N +RGPV+DEAALV+ L+   +   GLDVFE+EP
Sbjct: 214 VPLNEDTRHLVDAQILGRMKPDAILINTARGPVVDEAALVDALRSGVIAGAGLDVFEDEP 273

Query: 304 FMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVL----GRVKGYPI 349
            +  GLA+  N +++PH+ SA+   R  MA L+ALN +    GR+  +P+
Sbjct: 274 KLAAGLAELPNTVLLPHVGSATVRVRSEMARLSALNAIAIAEGRLPLHPV 323
>sp|Q9C4M5|GYAR_THELI Glyoxylate reductase (Glycolate reductase)
 dbj|BAB40320.1| glyoxylate reductase [Thermococcus litoralis]
          Length = 331

 Score =  196 bits (497), Expect = 3e-48,   Method: Composition-based stats.
 Identities = 121/264 (45%), Positives = 163/264 (61%), Gaps = 23/264 (8%)

Query: 88  KAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRG 147
           K  +  AVGY+N+D+E A K GI V NTPGVLT+ TA+LA +L LA ARRIVEAD F+R 
Sbjct: 69  KIIAQYAVGYDNIDIEEATKRGIYVTNTPGVLTDATADLAFALLLAVARRIVEADAFVRS 128

Query: 148 GLYE----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRL 203
           G ++    GW P +F+G  LKG+T+G++G GRIG A A+   +GF M +IY+   +    
Sbjct: 129 GEWKKSEVGWHPLMFLGYGLKGKTLGIVGFGRIGQALAKR-AKGFGMKIIYYSRTRKPEA 187

Query: 204 EKFVTA-YGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMM 262
           E+ + A Y  F                 E +L+E+D ISLH  L K TYH++ ++ L +M
Sbjct: 188 EEEIGAEYVDF-----------------ETLLKESDFISLHVPLTKETYHMIGEKELKLM 230

Query: 263 KKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIA 322
           K  AIL+N SRG V+D  AL++ LKE  +   GLDVFEEEP+    L   KN ++ PHI 
Sbjct: 231 KPNAILINTSRGAVVDTNALIKALKEGWIAGAGLDVFEEEPYYNEELFKLKNVVLAPHIG 290

Query: 323 SASKWTREGMATLAALNVLGRVKG 346
           SA+   REGMA L A N++   KG
Sbjct: 291 SATHEAREGMAELVAKNLIAFAKG 314
>ref|NP_148197.2| glyoxylate reductase [Aeropyrum pernix K1]
 sp|Q9YAW4|GYAR_AERPE Glyoxylate reductase (Glycolate reductase)
 dbj|BAA80834.2| glyoxylate reductase [Aeropyrum pernix K1]
          Length = 335

 Score =  194 bits (494), Expect = 8e-48,   Method: Composition-based stats.
 Identities = 114/262 (43%), Positives = 159/262 (60%), Gaps = 24/262 (9%)

Query: 91  SNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGG-- 148
           + MAVG++N+DVE A + GI V NTPGVLTE TAE   +L LAAARR+VEAD F+R G  
Sbjct: 73  AQMAVGFDNIDVECATRLGIYVTNTPGVLTEATAEFTWALILAAARRVVEADHFVRWGEW 132

Query: 149 --LYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKF 206
             L  GW P + +G  L+G+T+G++G GRIGS  A +  + F M +IY    +   +EK 
Sbjct: 133 WRLRTGWHPMMMLGVELRGKTLGILGMGRIGSRVAEIG-KAFGMRIIYHSRSRKREIEKE 191

Query: 207 VTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEA 266
           + A                   S+E++LRE+D++S+H  L   T HL+ +  L +MKK A
Sbjct: 192 LGA----------------EYRSLEDLLRESDILSIHLPLTDETRHLIGESELKLMKKTA 235

Query: 267 ILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPG--LADTKNAIVVPHIASA 324
           ILVN  RG ++D  ALV+ L+E  +    LDVFEEEP + P   L   KN ++ PH ASA
Sbjct: 236 ILVNTGRGAIVDTGALVKALREGWIAAAALDVFEEEP-LNPNHPLTAFKNVVLAPHAASA 294

Query: 325 SKWTREGMATLAALNVLGRVKG 346
           ++ TR  MA +AA N++   +G
Sbjct: 295 TRETRLRMAMMAAENLVAFAQG 316
>ref|ZP_02941201.1| Glyoxylate reductase [Cyanothece sp. PCC 8801]
 gb|EDT61237.1| Glyoxylate reductase [Cyanothece sp. PCC 8801]
          Length = 322

 Score =  194 bits (492), Expect = 1e-47,   Method: Composition-based stats.
 Identities = 117/271 (43%), Positives = 158/271 (58%), Gaps = 20/271 (7%)

Query: 88  KAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRG 147
           K  S MAVGY+N+DV+AA    I VG+TPGVLTE TA+L  +L +A  RR+ EA+++++ 
Sbjct: 70  KVISQMAVGYDNIDVQAATNREIPVGHTPGVLTEATADLTWALLMAITRRVTEAEDYIKQ 129

Query: 148 GLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFV 207
           G +  W P   +G+   G T+G+IG GRIG A AR    GF +N++Y    Q  RLE   
Sbjct: 130 GKWTTWQPMGLLGSDFVGATLGIIGLGRIGRAVAR-RARGFNLNILY---SQPHRLE--- 182

Query: 208 TAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAI 267
               Q L  N             E++L+E+D ISLH  L + TYHL+ K  L +MK+ A 
Sbjct: 183 VGLEQELGVN---------YVPFEQLLKESDFISLHTPLTEKTYHLIGKNELKLMKETAF 233

Query: 268 LVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKP-GLADTKNAIVVPHIASASK 326
           LVN +RG +ID+ AL + LK+  +    LDV E EP  K   L    N IV PHI SAS 
Sbjct: 234 LVNTARGGIIDQKALYDTLKQGEIAGAALDVTEPEPLPKDHQLLTLSNVIVTPHIGSASY 293

Query: 327 WTREGMATLAALNVLGRVKGYPIWHDPNRVD 357
            TR  MA +AA N+L  ++G P+   PN V+
Sbjct: 294 QTRSKMAIMAAQNLLAGLQGQPL---PNCVN 321
>ref|NP_578048.1| glyoxylate reductase [Pyrococcus furiosus DSM 3638]
 sp|Q8U3Y2|GYAR_PYRFU Glyoxylate reductase (Glycolate reductase)
 gb|AAL80443.1| putative phosphoglycerate dehydrogenase [Pyrococcus furiosus DSM
           3638]
          Length = 336

 Score =  193 bits (491), Expect = 2e-47,   Method: Composition-based stats.
 Identities = 115/298 (38%), Positives = 172/298 (57%), Gaps = 24/298 (8%)

Query: 53  EDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAV 112
           E +++ + D  D ++  L+E   + +F    +   +  +N AVGY+N+DVE A + GI V
Sbjct: 37  EKLLEKVKD-VDALVTMLSERIDQEVFENAPRL--RIVANYAVGYDNIDVEEATRRGIYV 93

Query: 113 GNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYE----GWLPHLFVGNLLKGQTV 168
            NTP VLT  TA+ A +L LA AR +V+ D+F+R G ++     W P  F+G  L G+T+
Sbjct: 94  TNTPDVLTNATADHAFALLLATARHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTI 153

Query: 169 GVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRAS 228
           G++G GRIG A AR   +GF M ++Y+   + ++ EK + A                   
Sbjct: 154 GIVGFGRIGQAIARR-AKGFNMRILYYSRTRKSQAEKELGA----------------EYR 196

Query: 229 SMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKE 288
            +EEVL+E+D + L   L K T +++N+ERL +MK  AILVN +RG V+D  AL++ LKE
Sbjct: 197 PLEEVLKESDFVILAVPLTKETMYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKE 256

Query: 289 NPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKG 346
             +   GLDVFEEEP+    L    N ++ PHI SA+   RE MA L A N++   +G
Sbjct: 257 GWIAGAGLDVFEEEPYYNEELFSLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRG 314
>ref|YP_001737977.1| Glyoxylate reductase [Candidatus Korarchaeum cryptofilum OPF8]
 gb|ACB08294.1| Glyoxylate reductase [Candidatus Korarchaeum cryptofilum OPF8]
          Length = 332

 Score =  192 bits (487), Expect = 5e-47,   Method: Composition-based stats.
 Identities = 124/295 (42%), Positives = 179/295 (60%), Gaps = 24/295 (8%)

Query: 55  IIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGN 114
           II+ + D CD ++  LT+     +F A  K   +  +  AVGY+N+DV+ A K GI V N
Sbjct: 39  IIERVKD-CDALVSLLTDPIDAEVFEAAPKL--RIVAQYAVGYDNIDVKEATKRGIYVTN 95

Query: 115 TPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYE-GWLPHLFVGNLLKGQTVGVIGA 173
           TPGVLTETTA+ A +L +AAARR+VEAD ++R G ++  W P + +G  + G+T+G++G 
Sbjct: 96  TPGVLTETTADFAFALLMAAARRVVEADRYVREGKWKVAWHPMMMLGYDVYGRTLGIVGM 155

Query: 174 GRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEV 233
           GRIG+A AR   +GF M ++Y+D   S R E F    G                  +E++
Sbjct: 156 GRIGAAVARR-AKGFGMRILYYD---SIRREDFEKELGV-------------EYVPLEKL 198

Query: 234 LREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFR 293
           L E+D +SLH  L + TYH++ +E+L  MK+ AILVN SRG V+D+ AL + LKE  +  
Sbjct: 199 LEESDFVSLHVPLTEETYHMIGEEQLRRMKRTAILVNTSRGKVVDQKALYKALKEGWIAG 258

Query: 294 VGLDVFEEEPFMKPG--LADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKG 346
            GLDVFE+EP + P   L   +N ++ PH ASAS  TR  MA + A N++   +G
Sbjct: 259 AGLDVFEQEP-IPPDDPLLKLENVVLAPHAASASHETRSRMAEMVAENLIAFKRG 312
>ref|YP_643402.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein
           [Rubrobacter xylanophilus DSM 9941]
 gb|ABG03590.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein
           [Rubrobacter xylanophilus DSM 9941]
          Length = 327

 Score =  191 bits (486), Expect = 7e-47,   Method: Composition-based stats.
 Identities = 119/271 (43%), Positives = 161/271 (59%), Gaps = 20/271 (7%)

Query: 88  KAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRG 147
           +  +NMAVGY+NVDV AA+  G+ V NTPGVL ETTA+ A  L +AAARR+ EA+  +R 
Sbjct: 68  RVVANMAVGYDNVDVAAASARGVVVTNTPGVLDETTADTAFMLLMAAARRLGEAERLVRS 127

Query: 148 GLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFV 207
           G +EGW P    G  + G+T+G++G GRIG A AR    GF M ++Y    +    E+ +
Sbjct: 128 GRWEGWGPEQLTGPDVWGKTLGIVGFGRIGRAVARRAT-GFGMRILYASRSRKEEAEREL 186

Query: 208 TAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAI 267
            A                R  S+EE+LRE+D +SLH  L   T HL+ +  L++MK  A+
Sbjct: 187 GA----------------RRVSLEELLRESDFVSLHTPLTPETRHLIGERELSLMKPAAV 230

Query: 268 LVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKW 327
           LVN +RGPV+DEAAL   L    +F  GLDV+E EP + P L   +NA++ PHI SAS  
Sbjct: 231 LVNTARGPVVDEAALAAALARRRIFAAGLDVYEREPEVHPALLGLENAVLAPHIGSASIE 290

Query: 328 TREGMATLAALNVLGRVKGYPIWHDPNRVDP 358
           TR  MA LAA N+   + G      P+ V+P
Sbjct: 291 TRARMAALAAENLRAVLSGR---RPPSPVNP 318
>ref|ZP_01439199.1| 2-hydroxyacid dehydrogenase [Fulvimarina pelagi HTCC2506]
 gb|EAU41280.1| 2-hydroxyacid dehydrogenase [Fulvimarina pelagi HTCC2506]
          Length = 322

 Score =  191 bits (485), Expect = 9e-47,   Method: Composition-based stats.
 Identities = 110/247 (44%), Positives = 148/247 (59%), Gaps = 15/247 (6%)

Query: 87  GKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMR 146
            K  ++  VGY+++D +AA K GI V NTP VL+E TA+LA +L L AARR  E +  +R
Sbjct: 70  AKIIASYGVGYSHIDTDAAKKAGIVVTNTPEVLSECTADLAMTLMLMAARRAGEGERELR 129

Query: 147 GGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKF 206
            G + GW P   +G  + G T GV+G GRIG   A+    GF M +IY+D +  +  EK 
Sbjct: 130 AGNWTGWRPTHMIGTKISGGTFGVLGFGRIGQEAAKRAHHGFGMKVIYYDAFPVSP-EK- 187

Query: 207 VTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEA 266
                    A   +P       S+E VL+EAD++SLH    K  YHL+N ERLAMMK  A
Sbjct: 188 -------AAATKAEP-----RDSIEAVLKEADVVSLHMPGGKENYHLINAERLAMMKPTA 235

Query: 267 ILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASK 326
           ILVN +RG V+D  AL + L    +   GLDVFE EP + P L +T NA+++PH+ SA+K
Sbjct: 236 ILVNSARGEVVDAKALADALNNGTIAGAGLDVFEGEPTIPPPLLET-NAVMLPHLGSATK 294

Query: 327 WTREGMA 333
           WTR+ M 
Sbjct: 295 WTRDAMG 301
Searching..................................................done Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|NP_176968.1|  HPR (HYDROXYPYRUVATE REDUCTASE); glycerate...   580   e-164
dbj|BAA19751.1|  hydroxypyruvate reductase [Arabidopsis thal...   580   e-164
gb|ABK96544.1|  unknown [Populus trichocarpa x Populus delto...   575   e-162
gb|ABL10359.1|  hydroxypyruvate reductase [Solenostemon scut...   571   e-161
dbj|BAB44155.1|  hydroxypyruvate reductase [Bruguiera gymnor...   570   e-161
emb|CAO47393.1|  unnamed protein product [Vitis vinifera]         568   e-160
gb|AAO73867.1|AF503361_1  putative NADH-dependent hydroxypyr...   566   e-159
emb|CAN65023.1|  hypothetical protein [Vitis vinifera]            565   e-159
dbj|BAG09374.1|  peroxisomal hydroxypyruvate reductase [Glyc...   564   e-159
dbj|BAA08410.1|  hydroxypyruvate reductase [Cucurbita cv. Ku...   564   e-159
gb|AAO73866.1|AF503360_1  putative NADH-dependent hydroxypyr...   563   e-159
sp|P13443|DHGY_CUCSA  Glycerate dehydrogenase (NADH-dependen...   561   e-158
dbj|BAA08411.1|  hydroxypyruvate reductase [Cucurbita cv. Ku...   556   e-157
gb|ABK21250.1|  unknown [Picea sitchensis]                        556   e-156
ref|NP_001045589.1|  Os02g0101500 [Oryza sativa (japonica cu...   554   e-156
ref|XP_001784621.1|  predicted protein [Physcomitrella paten...   511   e-143
ref|XP_001752353.1|  predicted protein [Physcomitrella paten...   502   e-140
gb|EAZ21390.1|  hypothetical protein OsJ_004873 [Oryza sativ...   488   e-136
gb|EAY84074.1|  hypothetical protein OsI_005307 [Oryza sativ...   484   e-135
ref|ZP_01666395.1|  D-isomer specific 2-hydroxyacid dehydrog...   462   e-128
ref|YP_001410651.1|  Glyoxylate reductase [Fervidobacterium ...   461   e-128
ref|YP_001471315.1|  D-isomer specific 2-hydroxyacid dehydro...   460   e-127
ref|ZP_01368724.1|  D-isomer specific 2-hydroxyacid dehydrog...   457   e-127
ref|NP_578048.1|  glyoxylate reductase [Pyrococcus furiosus ...   456   e-126
gb|ABD97861.1|  NADH-dependent hydroxypyruvate reductase [Pa...   454   e-126
ref|NP_422516.1|  2-hydroxyacid dehydrogenase [Caulobacter c...   452   e-125
ref|YP_517906.1|  hypothetical protein DSY1673 [Desulfitobac...   451   e-125
ref|XP_001691480.1|  hydroxypyruvate reductase [Chlamydomona...   449   e-124
ref|ZP_03856830.1|  lactate dehydrogenase-like oxidoreductas...   448   e-124
ref|YP_430795.1|  D-isomer specific 2-hydroxyacid dehydrogen...   447   e-124
ref|YP_001686676.1|  Glyoxylate reductase [Caulobacter sp. K...   447   e-124
ref|YP_001737977.1|  Glyoxylate reductase [Candidatus Korarc...   447   e-124
ref|YP_183096.1|  glyoxylate reductase [Thermococcus kodakar...   443   e-123
ref|YP_419558.1|  Lactate dehydrogenase and related dehydrog...   443   e-122
ref|ZP_02913953.1|  Glyoxylate reductase [Geobacillus sp. WC...   443   e-122
ref|ZP_00054933.1|  COG1052: Lactate dehydrogenase and relat...   441   e-122
ref|YP_762106.1|  glyoxylate reductase [Hyphomonas neptunium...   440   e-121
ref|ZP_01548851.1|  2-hydroxyacid dehydrogenase [Stappia agg...   437   e-121
sp|Q9C4M5|GYAR_THELI  Glyoxylate reductase (Glycolate reduct...   437   e-121
ref|YP_113865.1|  2-hydroxyacid dehydrogenase [Methylococcus...   435   e-120
ref|YP_001568546.1|  D-isomer specific 2-hydroxyacid dehydro...   435   e-120
ref|YP_001534304.1|  D-isomer specific 2-hydroxyacid dehydro...   434   e-120
ref|YP_920227.1|  Glyoxylate reductase [Thermofilum pendens ...   434   e-120
ref|ZP_01168688.1|  putative glycerate dehydrogenase [Bacill...   434   e-120
ref|ZP_01741677.1|  glycerate dehydrogenase [Rhodobacterales...   434   e-120
ref|ZP_01861538.1|  2-hydroxyacid dehydrogenase [Bacillus sp...   434   e-120
ref|NP_623521.1|  glyoxylate reductase [Thermoanaerobacter t...   433   e-119
ref|YP_148818.1|  2-hydroxyacid dehydrogenase [Geobacillus k...   433   e-119
ref|ZP_01444314.1|  2-hydroxyacid dehydrogenase [Roseovarius...   432   e-119
emb|CAO81265.1|  glyoxylate reductase (glycolate:NAD+ oxidor...   431   e-119
ref|YP_848018.1|  D-isomer specific 2-hydroxyacid dehydrogen...   430   e-119
ref|YP_077041.1|  putative glycerate dehydrogenase [Symbioba...   430   e-119
ref|YP_001127005.1|  Glycerate dehydrogenase [Geobacillus th...   430   e-118
ref|YP_001434366.1|  Glyoxylate reductase [Roseiflexus caste...   429   e-118
ref|ZP_02190699.1|  Lactate dehydrogenase and related dehydr...   429   e-118
emb|CAM75169.1|  Glyoxylate reductase [Magnetospirillum gryp...   429   e-118
ref|YP_001155374.1|  D-isomer specific 2-hydroxyacid dehydro...   427   e-118
ref|YP_001414898.1|  Glyoxylate reductase [Parvibaculum lava...   427   e-118
ref|YP_612475.1|  Glycolate reductase [Silicibacter sp. TM10...   427   e-117
ref|YP_001565752.1|  D-isomer specific 2-hydroxyacid dehydro...   426   e-117
ref|YP_001179183.1|  D-isomer specific 2-hydroxyacid dehydro...   426   e-117
ref|NP_384280.1|  2-hydroxyacid dehydrogenase [Sinorhizobium...   425   e-117
ref|ZP_02294079.1|  Glyoxylate reductase [Rhizobium legumino...   425   e-117
ref|YP_508857.1|  Glycolate reductase [Jannaschia sp. CCS1] ...   425   e-117
ref|YP_765750.1|  putative glyoxylate reductase [Rhizobium l...   425   e-117
ref|ZP_02855508.1|  Glyoxylate reductase [Rhizobium legumino...   424   e-117
emb|CAM32608.1|  Dehydrogenase oxidoreductase protein [Herba...   424   e-117
ref|ZP_02164852.1|  2-hydroxyacid dehydrogenase [Hoeflea pho...   424   e-117
ref|YP_001329036.1|  Glyoxylate reductase [Sinorhizobium med...   424   e-117
ref|ZP_02144459.1|  hypothetical protein RGBS107_02823 [Phae...   424   e-117
ref|YP_001662713.1|  D-isomer specific 2-hydroxyacid dehydro...   424   e-117
ref|YP_971639.1|  D-isomer specific 2-hydroxyacid dehydrogen...   423   e-116
ref|YP_001274602.1|  Glyoxylate reductase [Roseiflexus sp. R...   423   e-116
ref|YP_467690.1|  probable D-2-hydroxyacid dehydrogenase pro...   423   e-116
ref|YP_001099124.1|  putative glyoxylate reductase (Glycolat...   423   e-116
ref|ZP_02838365.1|  Glyoxylate reductase [Arthrobacter chlor...   422   e-116
ref|YP_001664595.1|  D-isomer specific 2-hydroxyacid dehydro...   422   e-116
ref|ZP_01750631.1|  Glycolate reductase [Roseobacter sp. CCS...   422   e-116
ref|ZP_01666712.1|  D-isomer specific 2-hydroxyacid dehydrog...   422   e-116
ref|ZP_02941201.1|  Glyoxylate reductase [Cyanothece sp. PCC...   422   e-116
ref|ZP_01521900.1|  D-isomer specific 2-hydroxyacid dehydrog...   422   e-116
ref|YP_986727.1|  D-isomer specific 2-hydroxyacid dehydrogen...   422   e-116
ref|NP_148197.2|  glyoxylate reductase [Aeropyrum pernix K1]...   421   e-116
ref|ZP_01904616.1|  pyrroline-5-carboxylate reductase [Roseo...   420   e-116
ref|ZP_02129818.1|  Glyoxylate reductase [Desulfatibacillum ...   420   e-116
ref|YP_676475.1|  D-isomer specific 2-hydroxyacid dehydrogen...   420   e-116
ref|NP_522506.1|  2-hydroxyacid dehydrogenase [Ralstonia sol...   420   e-116
ref|NP_436410.1|  2-hydroxyacid dehydrogenase [Sinorhizobium...   420   e-116
ref|YP_947693.1|  D-isomer specific 2-hydroxyacid dehydrogen...   420   e-116
ref|NP_540869.1|  2-hydroxyacid dehydrogenase [Brucella meli...   420   e-115
ref|ZP_00944908.1|  2-hydroxyacid dehydrogenase [Ralstonia s...   420   e-115
ref|YP_002827974.1|  2-hydroxyacid dehydrogenase [Rhizobium ...   420   e-115
ref|NP_391348.1|  gluconate 2-dehydrogenase [Bacillus subtil...   419   e-115
ref|YP_684368.1|  glyoxylate reductase [Roseobacter denitrif...   419   e-115
ref|YP_001328057.1|  D-isomer specific 2-hydroxyacid dehydro...   419   e-115
ref|ZP_01037723.1|  2-hydroxyacid dehydrogenase [Roseovarius...   418   e-115
ref|YP_001831652.1|  Glyoxylate reductase [Beijerinckia indi...   418   e-115
ref|YP_001190357.1|  Glyoxylate reductase [Metallosphaera se...   418   e-115
ref|ZP_00960504.1|  2-hydroxyacid dehydrogenase [Roseovarius...   417   e-115
ref|YP_615831.1|  Glycolate reductase [Sphingopyxis alaskens...   417   e-115
ref|ZP_01035877.1|  D-isomer specific 2-hydroxyacid dehydrog...   417   e-115
ref|NP_699151.1|  2-hydroxyacid dehydrogenase [Brucella suis...   417   e-115
ref|YP_520253.1|  hypothetical protein DSY4020 [Desulfitobac...   417   e-115
ref|YP_001352411.1|  2-hydroxyacid dehydrogenase [Janthinoba...   417   e-115
ref|ZP_01054845.1|  2-hydroxyacid dehydrogenase [Roseobacter...   417   e-115
ref|ZP_02121344.1|  Glyoxylate reductase [Methylobacterium n...   417   e-114
ref|YP_001020708.1|  putative 2-hydroxyacid dehydrogenase [M...   417   e-114
ref|ZP_01003291.1|  2-hydroxyacid dehydrogenase [Loktanella ...   417   e-114
ref|NP_353111.1|  D-isomer specific 2-hydroxyacid dehydrogen...   416   e-114
ref|YP_222806.1|  2-hydroxyacid dehydrogenase [Brucella abor...   416   e-114
ref|ZP_01878191.1|  D-isomer specific 2-hydroxyacid dehydrog...   416   e-114
ref|ZP_01447132.1|  2-hydroxyacid dehydrogenase [alpha prote...   416   e-114
ref|ZP_01012068.1|  D-isomer specific 2-hydroxyacid dehydrog...   415   e-114
ref|ZP_02147929.1|  2-hydroxyacid dehydrogenase [Phaeobacter...   415   e-114
ref|YP_001896547.1|  D-isomer specific 2-hydroxyacid dehydro...   415   e-114
ref|YP_428871.1|  Glycolate reductase [Rhodospirillum rubrum...   414   e-114
ref|ZP_01187992.1|  D-isomer specific 2-hydroxyacid dehydrog...   414   e-114
ref|YP_559944.1|  Putative 2-ketogluconate reductase [Burkho...   414   e-114
ref|YP_001369285.1|  Glyoxylate reductase [Ochrobactrum anth...   414   e-114
ref|ZP_01902582.1|  2-hydroxyacid dehydrogenase [Roseobacter...   414   e-114
ref|ZP_02947547.1|  Glyoxylate reductase [Methylocella silve...   413   e-113
ref|ZP_01753096.1|  2-hydroxyacid dehydrogenase [Roseobacter...   413   e-113
ref|YP_001696599.1|  Glyoxylate reductase [Lysinibacillus sp...   413   e-113
ref|ZP_01173412.1|  hypothetical protein B14911_09477 [Bacil...   413   e-113
ref|YP_001935995.1|  2-hydroxyacid dehydrogenase [Brucella a...   412   e-113
ref|YP_001923204.1|  D-isomer specific 2-hydroxyacid dehydro...   412   e-113
ref|YP_352368.1|  2-hydroxyacid dehydrogenase [Rhodobacter s...   412   e-113
ref|YP_001419005.1|  Glyoxylate reductase [Xanthobacter auto...   411   e-113
ref|YP_001306138.1|  D-isomer specific 2-hydroxyacid dehydro...   411   e-113
ref|ZP_02153103.1|  D-isomer specific 2-hydroxyacid dehydrog...   410   e-113
ref|YP_001042870.1|  Glyoxylate reductase [Rhodobacter sphae...   410   e-113
ref|YP_001769127.1|  Glyoxylate reductase [Methylobacterium ...   410   e-113
ref|ZP_02056254.1|  Glyoxylate reductase [Methylobacterium c...   410   e-113
ref|YP_001488104.1|  D-isomer specific 2-hydroxyacid dehydro...   410   e-113
ref|ZP_00956178.1|  2-hydroxyacid dehydrogenase [Sulfitobact...   410   e-112
gb|EDT28874.1|  glyoxylate reductase [Oligotropha carboxidov...   410   e-112
ref|YP_080512.1|  D-isomer specific 2-hydroxyacid dehydrogen...   409   e-112
ref|YP_001422754.1|  YvcT [Bacillus amyloliquefaciens FZB42]...   409   e-112
ref|YP_001755355.1|  D-isomer specific 2-hydroxyacid dehydro...   409   e-112
ref|YP_080803.1|  probable 2-ketogluconate reductase YvcT [B...   409   e-112
ref|ZP_01014196.1|  2-hydroxyacid dehydrogenase [Rhodobacter...   409   e-112
ref|ZP_02887490.1|  D-isomer specific 2-hydroxyacid dehydrog...   408   e-112
ref|NP_244180.1|  glycerate dehydrogenase [Bacillus halodura...   408   e-112
ref|ZP_01755592.1|  D-isomer specific 2-hydroxyacid dehydrog...   408   e-112
ref|YP_001791021.1|  D-isomer specific 2-hydroxyacid dehydro...   408   e-112
ref|ZP_02171588.1|  protein of unknown function DUF881 [Baci...   407   e-111
ref|YP_727037.1|  lactate dehydrogenase or related dehydroge...   406   e-111
ref|YP_166811.1|  2-hydroxyacid dehydrogenase [Silicibacter ...   406   e-111
ref|ZP_02989735.1|  D-isomer specific 2-hydroxyacid dehydrog...   406   e-111
ref|YP_681501.1|  glyoxylate reductase [Roseobacter denitrif...   405   e-111
ref|ZP_03938310.1|  possible glyoxylate reductase [Lactobaci...   405   e-111
ref|NP_693278.1|  glycerate dehydrogenase [Oceanobacillus ih...   405   e-111
ref|ZP_03941324.1|  possible glyoxylate reductase [Lactobaci...   405   e-111
ref|ZP_03953531.1|  possible glyoxylate reductase [Lactobaci...   405   e-111
ref|ZP_02142939.1|  glyoxylate reductase [Roseobacter litora...   404   e-111
ref|YP_001857046.1|  D-isomer specific 2-hydroxyacid dehydro...   404   e-111
ref|YP_001523152.1|  putative dehydrogenase [Azorhizobium ca...   404   e-111
ref|YP_165887.1|  2-hydroxyacid dehydrogenase [Silicibacter ...   404   e-111
ref|YP_484238.1|  Glycolate reductase [Rhodopseudomonas palu...   403   e-111
ref|XP_854862.1|  PREDICTED: similar to Glyoxylate reductase...   403   e-110
ref|ZP_01439199.1|  2-hydroxyacid dehydrogenase [Fulvimarina...   402   e-110
ref|XP_580934.3|  PREDICTED: similar to Chain A, Ternary Cry...   402   e-110
ref|ZP_02151949.1|  2-hydroxyacid dehydrogenase [Oceanibulbu...   402   e-110
ref|YP_001488322.1|  gluconate 2-dehydrogenase [Bacillus pum...   402   e-110
ref|NP_867230.1|  probable 2-hydroxyacid dehydrogenase [Rhod...   402   e-110
gb|AAB18530.1|  unnamed protein product [Escherichia coli]        401   e-110
ref|YP_643402.1|  D-isomer specific 2-hydroxyacid dehydrogen...   401   e-110
ref|ZP_01741000.1|  D-isomer specific 2-hydroxyacid dehydrog...   401   e-110
ref|YP_296488.1|  2-hydroxyacid dehydrogenase [Ralstonia eut...   400   e-110
ref|YP_683614.1|  glyoxylate reductase [Roseobacter denitrif...   400   e-110
ref|ZP_00961432.1|  D-isomer specific 2-hydroxyacid dehydrog...   400   e-110
ref|YP_001168382.1|  Glyoxylate reductase [Rhodobacter sphae...   400   e-109
dbj|BAA29686.1|  376aa long hypothetical dehydrogenase [Pyro...   400   e-109
ref|YP_612620.1|  D-isomer specific 2-hydroxyacid dehydrogen...   400   e-109
ref|ZP_01045151.1|  2-hydroxyacid dehydrogenase [Nitrobacter...   399   e-109
gb|ABB68037.1|  putative dehydrogenase [Shigella boydii Sb227]    399   e-109
ref|ZP_02007136.1|  Gluconate 2-dehydrogenase [Ralstonia pic...   399   e-109
ref|YP_259824.1|  2-ketogluconate 6-phosphate reductase, put...   399   e-109
ref|YP_409865.2|  putative dehydrogenase [Shigella boydii Sb...   399   e-109
ref|XP_424417.2|  PREDICTED: similar to MGC82214 protein [Ga...   399   e-109
ref|NP_001107226.1|  glyoxylate reductase/hydroxypyruvate re...   399   e-109
ref|ZP_01055090.1|  D-isomer specific 2-hydroxyacid dehydrog...   399   e-109
ref|ZP_02293529.1|  D-isomer specific 2-hydroxyacid dehydrog...   398   e-109
ref|NP_036335.1|  glyoxylate reductase/hydroxypyruvate reduc...   398   e-109
pdb|2GCG|A  Chain A, Ternary Crystal Structure Of Human Glyo...   398   e-109
ref|YP_001155168.1|  D-isomer specific 2-hydroxyacid dehydro...   398   e-109
ref|YP_543052.1|  putative dehydrogenase [Escherichia coli U...   398   e-109
ref|ZP_00711407.1|  COG1052: Lactate dehydrogenase and relat...   398   e-109
ref|YP_001337568.1|  2-hydroxyacid dehydrogenase [Klebsiella...   397   e-109
ref|ZP_02387834.1|  glyoxylate reductase [Burkholderia thail...   397   e-109
ref|YP_001460346.1|  2-ketogluconate reductase [Escherichia ...   397   e-109
ref|YP_001723172.1|  D-isomer specific 2-hydroxyacid dehydro...   397   e-109
emb|CAH89789.1|  hypothetical protein [Pongo abelii]              397   e-109
ref|YP_364607.1|  2-hydroxyacid dehydrogenase [Xanthomonas c...   397   e-109
ref|YP_523399.1|  D-isomer specific 2-hydroxyacid dehydrogen...   397   e-109
gb|AAN82808.1|AE016768_226  2-ketogluconate reductase [Esche...   397   e-109
ref|XP_001504338.1|  PREDICTED: similar to Chain A, Ternary ...   397   e-109
ref|ZP_00726400.1|  COG1052: Lactate dehydrogenase and relat...   397   e-109
ref|NP_756234.2|  2-hydroxyacid dehydrogenase [Escherichia c...   397   e-108
gb|ABB64241.1|  putative dehydrogenase [Shigella dysenteriae...   397   e-108
ref|ZP_02464263.1|  2-hydroxyacid dehydrogenase [Burkholderi...   397   e-108
ref|YP_109051.1|  2-hydroxyacid dehydrogenase [Burkholderia ...   396   e-108
ref|YP_405732.2|  putative dehydrogenase [Shigella dysenteri...   396   e-108
ref|YP_442235.2|  glyoxylate reductase [Burkholderia thailan...   396   e-108
ref|ZP_01228415.1|  D-isomer specific 2-hydroxyacid dehydrog...   396   e-108
ref|ZP_02373994.1|  glyoxylate reductase [Burkholderia thail...   396   e-108
ref|ZP_02737749.1|  probable 2-hydroxyacid dehydrogenase [Ge...   396   e-108
ref|YP_996837.1|  D-isomer specific 2-hydroxyacid dehydrogen...   396   e-108
gb|AAZ90377.1|  putative dehydrogenase [Shigella sonnei Ss046]    396   e-108
ref|AP_004241.1|  2-keto-D-gluconate reductase [Escherichia ...   396   e-108
ref|ZP_00923022.1|  COG1052: Lactate dehydrogenase and relat...   396   e-108
gb|ABC36478.1|  glyoxylate reductase [Burkholderia thailande...   396   e-108
ref|YP_312612.2|  putative dehydrogenase [Shigella sonnei Ss...   396   e-108
ref|YP_002807903.1|  conserved hypothetical protein [Escheri...   396   e-108
ref|NP_106212.1|  2-hydroxyacid dehydrogenase [Mesorhizobium...   396   e-108
ref|ZP_02356479.1|  glyoxylate reductase [Burkholderia oklah...   395   e-108
ref|ZP_02139806.1|  glyoxylate reductase [Roseobacter litora...   395   e-108
ref|YP_001745839.1|  2-ketogluconate reductase [Escherichia ...   395   e-108
ref|ZP_01370695.1|  D-isomer specific 2-hydroxyacid dehydrog...   395   e-108
ref|YP_981857.1|  D-isomer specific 2-hydroxyacid dehydrogen...   395   e-108
gb|AAU49757.1|  glyoxylate reductase [Burkholderia mallei AT...   395   e-108
ref|ZP_00998168.1|  D-isomer specific 2-hydroxyacid dehydrog...   395   e-108
ref|NP_643033.1|  2-hydroxyacid dehydrogenase [Xanthomonas a...   395   e-108
ref|ZP_01320783.1|  hypothetical protein BpseP_03005472 [Bur...   395   e-108
ref|YP_002763306.1|  putative oxidoreductase [Gemmatimonas a...   395   e-108
ref|NP_142561.2|  glyoxylate reductase [Pyrococcus horikoshi...   395   e-108
ref|YP_993802.1|  glyoxylate reductase [Burkholderia mallei ...   395   e-108
ref|NP_001018361.1|  glyoxylate reductase/hydroxypyruvate re...   395   e-108
ref|ZP_01747987.1|  2-hydroxyacid dehydrogenase [Sagittula s...   395   e-108
ref|YP_549890.1|  D-isomer specific 2-hydroxyacid dehydrogen...   395   e-108
ref|NP_839339.1|  2-hydroxyacid dehydrogenase [Shigella flex...   394   e-108
ref|YP_001764361.1|  D-isomer specific 2-hydroxyacid dehydro...   394   e-108
ref|YP_253938.1|  hypothetical protein SH2023 [Staphylococcu...   394   e-108
ref|YP_519675.1|  hypothetical protein DSY3442 [Desulfitobac...   394   e-108
gb|EEJ90696.1|  lactate dehydrogenase-like oxidoreductase [M...   394   e-108
ref|ZP_02145180.1|  D-isomer specific 2-hydroxyacid dehydrog...   394   e-108
ref|YP_001903018.1|  Putative gluconate 2-dehydrogenase [Xan...   394   e-108
ref|ZP_02243841.1|  2-hydroxyacid dehydrogenase [Xanthomonas...   394   e-108
ref|ZP_00717959.1|  COG1052: Lactate dehydrogenase and relat...   394   e-108
ref|ZP_01696182.1|  D-isomer specific 2-hydroxyacid dehydrog...   394   e-108
ref|YP_001440192.1|  hypothetical protein ESA_04175 [Enterob...   393   e-108
ref|YP_001476295.1|  D-isomer specific 2-hydroxyacid dehydro...   393   e-108
ref|YP_620507.1|  D-isomer specific 2-hydroxyacid dehydrogen...   393   e-107
ref|ZP_01444482.1|  D-isomer specific 2-hydroxyacid dehydrog...   393   e-107
ref|ZP_02456664.1|  D-isomer specific 2-hydroxyacid dehydrog...   393   e-107
ref|NP_386583.1|  2-hydroxyacid dehydrogenase [Sinorhizobium...   393   e-107
ref|YP_001028734.1|  glyoxylate reductase [Burkholderia mall...   393   e-107
gb|AAS64128.1|  putative D-isomer specific 2-hydroxyaciddehy...   393   e-107
ref|YP_690875.1|  putative dehydrogenase [Shigella flexneri ...   393   e-107
ref|YP_201899.1|  2-hydroxyacid dehydrogenase [Xanthomonas o...   393   e-107
ref|ZP_00982051.1|  COG1052: Lactate dehydrogenase and relat...   393   e-107
ref|ZP_02114627.1|  D-isomer specific 2-hydroxyacid dehydrog...   393   e-107
ref|ZP_02499004.1|  D-isomer specific 2-hydroxyacid dehydrog...   393   e-107
emb|CAE30406.1|  novel protein similar to human glyoxylate r...   392   e-107
ref|NP_637898.1|  2-hydroxyacid dehydrogenase [Xanthomonas c...   392   e-107
ref|ZP_03960213.1|  glyoxylate reductase [Lactobacillus vagi...   392   e-107
ref|YP_452117.1|  2-hydroxyacid dehydrogenase [Xanthomonas o...   392   e-107
ref|XP_973278.1|  PREDICTED: similar to CG1236-PA [Tribolium...   392   e-107
ref|ZP_02901457.1|  2-ketogluconate reductase [Escherichia a...   391   e-107
ref|ZP_00986479.1|  COG1052: Lactate dehydrogenase and relat...   391   e-107
ref|YP_001067117.1|  D-isomer specific 2-hydroxyacid dehydro...   391   e-107
ref|ZP_00953778.1|  D-isomer specific 2-hydroxyacid dehydrog...   391   e-107
ref|ZP_01448595.1|  2-hydroxyacid dehydrogenase [alpha prote...   391   e-107
ref|ZP_02403830.1|  glyoxylate reductase [Burkholderia pseud...   391   e-107
ref|YP_368457.1|  2-hydroxyacid dehydrogenase [Burkholderia ...   391   e-107
ref|YP_683665.1|  D-isomer specific 2-hydroxyacid dehydrogen...   391   e-107
ref|ZP_00824069.1|  COG1052: Lactate dehydrogenase and relat...   390   e-107
gb|AAM87639.1|AE014011_6  putative dehydrogenase [Yersinia p...   390   e-107
ref|ZP_01755871.1|  glycerate dehydrogenase [Roseobacter sp....   390   e-107
ref|YP_001679796.1|  glyoxylate reductase [Heliobacterium mo...   390   e-107
ref|YP_001059830.1|  glyoxylate reductase [Burkholderia pseu...   390   e-107
ref|NP_407503.1|  2-hydroxyacid dehydrogenase [Yersinia pest...   390   e-106
ref|ZP_01039826.1|  2-hydroxyacid dehydrogenase [Erythrobact...   390   e-106
ref|ZP_02482681.1|  D-isomer specific 2-hydroxyacid dehydrog...   390   e-106
ref|YP_273367.1|  D-isomer specific 2-hydroxyacid dehydrogen...   390   e-106
ref|YP_001174908.1|  D-isomer specific 2-hydroxyacid dehydro...   390   e-106
ref|YP_040314.1|  D-isomer specific 2-hydroxyacid dehydrogen...   390   e-106
ref|ZP_02139703.1|  D-isomer specific 2-hydroxyacid dehydrog...   389   e-106
ref|YP_497579.1|  Glycolate reductase [Novosphingobium aroma...   389   e-106
ref|YP_001909347.1|  2-ketogluconate reductase [Erwinia tasm...   389   e-106
ref|ZP_00948323.1|  D-isomer specific 2-hydroxyacid dehydrog...   389   e-106
ref|ZP_02355535.1|  gluconate 2-dehydrogenase [Burkholderia ...   389   e-106
ref|YP_346668.1|  2-hydroxyacid dehydrogenase [Pseudomonas f...   389   e-106
ref|ZP_00629674.1|  Glycolate reductase [Paracoccus denitrif...   388   e-106
ref|YP_809687.1|  Lactate dehydrogenase related enzyme [Oeno...   388   e-106
ref|ZP_01862964.1|  D-isomer specific 2-hydroxyacid dehydrog...   388   e-106
ref|YP_001167531.1|  D-isomer specific 2-hydroxyacid dehydro...   388   e-106
ref|YP_001008293.1|  putative D-isomer specific 2-hydroxyaci...   388   e-106
ref|YP_001376714.1|  D-isomer specific 2-hydroxyacid dehydro...   388   e-106
Sequences not found previously or not previously below threshold:

ref|YP_530248.1|  D-isomer specific 2-hydroxyacid dehydrogen...   401   e-110
ref|YP_779183.1|  Glyoxylate reductase [Rhodopseudomonas pal...   401   e-110
ref|YP_316657.1|  2-hydroxyacid dehydrogenase [Nitrobacter w...   400   e-110
ref|YP_001236280.1|  putative Glyoxylate reductase [Bradyrhi...   398   e-109
ref|YP_001202288.1|  putative D-isomer specific 2-hydroxyaci...   398   e-109
ref|NP_001084647.1|  hypothetical protein LOC414606 [Xenopus...   395   e-108
ref|NP_945775.1|  2-hydroxyacid dehydrogenase [Rhodopseudomo...   395   e-108
ref|NP_525028.1|  glyoxylate reductase/hydroxypyruvate reduc...   394   e-108
ref|YP_567358.1|  D-isomer specific 2-hydroxyacid dehydrogen...   392   e-107
ref|YP_575406.1|  Glycolate reductase [Nitrobacter hamburgen...   392   e-107
ref|ZP_01439868.1|  2-hydroxyacid dehydrogenase [Fulvimarina...   388   e-106
>ref|NP_176968.1| HPR (HYDROXYPYRUVATE REDUCTASE); glycerate dehydrogenase/ poly(U)
           binding [Arabidopsis thaliana]
 gb|AAG52006.1|AC012563_16 hydroxypyruvate reductase (HPR); 50972-48670 [Arabidopsis thaliana]
 gb|AAK44036.1|AF370221_1 putative hydroxypyruvate reductase HPR [Arabidopsis thaliana]
 gb|AAM20404.1| hydroxypyruvate reductase (HPR) [Arabidopsis thaliana]
 gb|AAM44919.1| putative hydroxypyruvate reductase [Arabidopsis thaliana]
 gb|AAN65124.1| hydroxypyruvate reductase (HPR) [Arabidopsis thaliana]
 dbj|BAE98694.1| hydroxypyruvate reductase [Arabidopsis thaliana]
          Length = 386

 Score =  580 bits (1497), Expect = e-164,   Method: Composition-based stats.
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG
Sbjct: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL
Sbjct: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENASPPNASPSIVNSKALGLPVSKL
Sbjct: 361 NENASPPNASPSIVNSKALGLPVSKL 386
>dbj|BAA19751.1| hydroxypyruvate reductase [Arabidopsis thaliana]
          Length = 386

 Score =  580 bits (1495), Expect = e-164,   Method: Composition-based stats.
 Identities = 384/386 (99%), Positives = 384/386 (99%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG
Sbjct: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVI EAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIHEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEPFMKPGLAD KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL
Sbjct: 301 EEPFMKPGLADMKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENASPPNASPSIVNSKALGLPVSKL
Sbjct: 361 NENASPPNASPSIVNSKALGLPVSKL 386
>gb|ABK96544.1| unknown [Populus trichocarpa x Populus deltoides]
          Length = 386

 Score =  575 bits (1482), Expect = e-162,   Method: Composition-based stats.
 Identities = 345/386 (89%), Positives = 371/386 (96%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEVYNPNGKYRVVSTK MPGTRWINLL++Q CRVEIC  KKTILSVEDII LIG
Sbjct: 1   MAKPISIEVYNPNGKYRVVSTKSMPGTRWINLLIEQDCRVEICTQKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLF+ALS+AGGKAFSNMAVGYNNVDV AANK+G+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFAALSRAGGKAFSNMAVGYNNVDVNAANKHGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEAD+FMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAYG+FLKANGEQPVTWKRA+SM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYGEFLKANGEQPVTWKRAASMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHP+LDKTTYHL+NKE LA MKKEAILVNCSRGPV+DE ALVEHLK+NPMFRVGLDVFE
Sbjct: 241 SLHPILDKTTYHLINKESLATMKKEAILVNCSRGPVVDEVALVEHLKQNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNA+VVPHIASASKWTREGMATLAALNVLG++KGYP+W DPN+V PFL
Sbjct: 301 DEPYMKPGLADMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGDPNQVAPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP ASPSIVN+KALGLPVSKL
Sbjct: 361 NENAPPPAASPSIVNAKALGLPVSKL 386
>gb|ABL10359.1| hydroxypyruvate reductase [Solenostemon scutellarioides]
          Length = 386

 Score =  571 bits (1472), Expect = e-161,   Method: Composition-based stats.
 Identities = 346/386 (89%), Positives = 366/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+ +EVYNPNGKYRVVSTK MPGTRWINLLVDQ CR+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPLQVEVYNPNGKYRVVSTKSMPGTRWINLLVDQDCRLEICTEKKTILSVEDIISLIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           +KCDGVIGQLTEDWGE LFSALS+AGG AFSNMAVGYNNVDV+AANK+G+AVGNTPGVLT
Sbjct: 61  NKCDGVIGQLTEDWGEKLFSALSRAGGTAFSNMAVGYNNVDVDAANKHGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAYGQFL+ANGEQPVTWKRASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYGQFLQANGEQPVTWKRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAILVNCSRGPVIDE ALVEHLK+NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILVNCSRGPVIDEVALVEHLKQNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGL   KNAI+VPHIASASKWTREGMATLAALNVLG++KGYPIW DPN V PFL
Sbjct: 301 DEPYMKPGLEKMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPIWGDPNNVAPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NEN+ PP A PSIVNSKALGLPVSKL
Sbjct: 361 NENSPPPAACPSIVNSKALGLPVSKL 386
>dbj|BAB44155.1| hydroxypyruvate reductase [Bruguiera gymnorrhiza]
          Length = 386

 Score =  570 bits (1471), Expect = e-161,   Method: Composition-based stats.
 Identities = 346/386 (89%), Positives = 369/386 (95%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP G+YRVVSTKPMPGTRWINLLV Q CR+EIC  KKTILSVEDII L+G
Sbjct: 1   MAKPVSIEVWNPRGRYRVVSTKPMPGTRWINLLVQQDCRLEICTEKKTILSVEDIIALMG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLF+ALSKAGGKAFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFAALSKAGGKAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR GLY+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGLYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQ+TRLEKFVTAYGQFLKANGEQPVTWKRA++M+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQATRLEKFVTAYGQFLKANGEQPVTWKRAATMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHL+NKE LA MKKEA+LVNCSRGPVIDE ALVEHL+ NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLINKESLASMKKEAVLVNCSRGPVIDEVALVEHLRRNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAIVVPHIASASKWTREGMATLAALNVLG++KGYP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGDPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP A PSIVNSKALGLPVSKL
Sbjct: 361 NENAPPPAACPSIVNSKALGLPVSKL 386
>emb|CAO47393.1| unnamed protein product [Vitis vinifera]
          Length = 418

 Score =  568 bits (1465), Expect = e-160,   Method: Composition-based stats.
 Identities = 343/380 (90%), Positives = 367/380 (96%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP GKYRVVSTKPMPGTRWI+LLV Q CRVEIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPCGKYRVVSTKPMPGTRWIDLLVQQDCRVEICTQKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALS+AGG+AFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSRAGGRAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLS+AAARRIVEADEFMR GLY+GWLPHLFVGNLL+GQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSMAAARRIVEADEFMRAGLYDGWLPHLFVGNLLRGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQ+TRLEKFVTAYGQFLKA+GEQPVTWKRA+SM+EVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYYDLYQATRLEKFVTAYGQFLKASGEQPVTWKRAASMDEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERL+MMKKEAIL+NCSRGPVIDE ALV HLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLSMMKKEAILINCSRGPVIDEVALVAHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG++KGYPIWHDPN+V+PFL
Sbjct: 301 DEPYMKPGLAEMKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPIWHDPNKVEPFL 360

Query: 361 NENASPPNASPSIVNSKALG 380
           NEN+ PP ASPSIVN+KALG
Sbjct: 361 NENSLPPAASPSIVNAKALG 380
>gb|AAO73867.1|AF503361_1 putative NADH-dependent hydroxypyruvate reductase [Glycine max]
          Length = 386

 Score =  566 bits (1460), Expect = e-159,   Method: Composition-based stats.
 Identities = 344/386 (89%), Positives = 365/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP+GKYRVVSTKPMPGTRWINLL+    R+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPSGKYRVVSTKPMPGTRWINLLIQNDVRLEICTEKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALSKAGGKAFSNMAVGYNNVDV+AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEELFSALSKAGGKAFSNMAVGYNNVDVDAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASL+LAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLTLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAY  FLKANGE PVTWKRA++M+EVL+EAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYAAFLKANGETPVTWKRAATMDEVLQEADII 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAIL+NCSRGPVIDEAALVEHLK NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILINCSRGPVIDEAALVEHLKHNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG+VKGYP+W D NRV+PFL
Sbjct: 301 EEPYMKPGLAELKNAIVVPHIASASKWTREGMATLAALNVLGKVKGYPVWFDANRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP A PSIVN+KALGLP SKL
Sbjct: 361 NENARPPAACPSIVNAKALGLPTSKL 386
>emb|CAN65023.1| hypothetical protein [Vitis vinifera]
          Length = 386

 Score =  565 bits (1456), Expect = e-159,   Method: Composition-based stats.
 Identities = 342/379 (90%), Positives = 366/379 (96%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP GKYRVVSTKPMPGTRWI+LLV Q CRVEIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPCGKYRVVSTKPMPGTRWIDLLVQQDCRVEICTQKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALS+AGG+AFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSRAGGRAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLS+AAARRIVEADEFMR GLY+GWLPHLFVGNLL+GQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSMAAARRIVEADEFMRAGLYDGWLPHLFVGNLLRGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQ+TRLEKFVTAYGQFLKA+GEQPVTWKRA+SM+EVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYYDLYQATRLEKFVTAYGQFLKASGEQPVTWKRAASMDEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERL+MMKKEAIL+NCSRGPVIDE ALV HLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLSMMKKEAILINCSRGPVIDEVALVAHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG++KGYPIWHDPN+V+PFL
Sbjct: 301 DEPYMKPGLAEMKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPIWHDPNKVEPFL 360

Query: 361 NENASPPNASPSIVNSKAL 379
           NEN+ PP ASPSIVN+KAL
Sbjct: 361 NENSLPPAASPSIVNAKAL 379
>dbj|BAG09374.1| peroxisomal hydroxypyruvate reductase [Glycine max]
          Length = 386

 Score =  564 bits (1455), Expect = e-159,   Method: Composition-based stats.
 Identities = 343/386 (88%), Positives = 365/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP+GKYRVVSTKPMPGTRWINLL+    R+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPSGKYRVVSTKPMPGTRWINLLIQNDVRLEICTEKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALSKAGGKAFSNMAVGYNNVDV+AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEELFSALSKAGGKAFSNMAVGYNNVDVDAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASL+LAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLTLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAY  FLKANGE PVTWKRA++M+EVL+EAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYAAFLKANGETPVTWKRAATMDEVLQEADII 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAIL+NCSRGPVIDEAALVEHLK NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILINCSRGPVIDEAALVEHLKHNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG+VKGYP+W D N+V+PFL
Sbjct: 301 EEPYMKPGLAELKNAIVVPHIASASKWTREGMATLAALNVLGKVKGYPVWFDANKVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP A PSIVN+KALGLP SKL
Sbjct: 361 NENARPPAACPSIVNAKALGLPTSKL 386
>dbj|BAA08410.1| hydroxypyruvate reductase [Cucurbita cv. Kurokawa Amakuri]
          Length = 386

 Score =  564 bits (1455), Expect = e-159,   Method: Composition-based stats.
 Identities = 340/386 (88%), Positives = 364/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MA  V +EV+NPNGKYRVVSTKPMPGTRWINLL++Q CRVEIC  KKTILSVEDI+ LIG
Sbjct: 1   MANRVQVEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDIVALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALS+AG KAFSNMAVGYNNVDV AANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEVLFSALSRAGCKAFSNMAVGYNNVDVNAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR G Y+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGHYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEVPVTWRRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTT+HLVNKE L  MKK+AIL+NCSRGPVIDEAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAI+VPHIASASKWTREGMATLAALNVLG++K YP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKQYPVWADPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           +ENA PP ASPSIVN+KAL LPVSKL
Sbjct: 361 DENAPPPAASPSIVNAKALELPVSKL 386
>gb|AAO73866.1|AF503360_1 putative NADH-dependent hydroxypyruvate reductase [Glycine max]
          Length = 386

 Score =  563 bits (1453), Expect = e-159,   Method: Composition-based stats.
 Identities = 343/386 (88%), Positives = 366/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP+GKYRVVSTKPMPGTRWINLLV    R+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPSGKYRVVSTKPMPGTRWINLLVQNDVRLEICTEKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFS LSKAGGKAFSNMAVGYNNVDV+AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEQLFSTLSKAGGKAFSNMAVGYNNVDVDAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKF+TAY  FLKA+GE PVTWKRA++M+EVL+EAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFITAYATFLKASGETPVTWKRAATMDEVLQEADII 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAIL+NCSRGPVIDEAALVEHLK+NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILINCSRGPVIDEAALVEHLKQNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG++KGYP+W D NRV+PFL
Sbjct: 301 EEPYMKPGLAELKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPVWFDANRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP ASPSIVN+KALGLP SKL
Sbjct: 361 NENAQPPAASPSIVNAKALGLPTSKL 386
>sp|P13443|DHGY_CUCSA Glycerate dehydrogenase (NADH-dependent hydroxypyruvate reductase)
           (HPR) (GDH)
 emb|CAA41434.1| NADH-dependent hydroxypyruvate reductase [Cucumis sativus]
 emb|CAA32764.1| unnamed protein product [Cucumis sativus]
          Length = 382

 Score =  561 bits (1447), Expect = e-158,   Method: Composition-based stats.
 Identities = 336/380 (88%), Positives = 363/380 (95%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPV IEV+NPNGKYRVVSTKPMPGTRWINLL++Q CRVEIC  KKTILSVEDI+ LIG
Sbjct: 1   MAKPVQIEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDILALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALS+AGGKAFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEVLFSALSRAGGKAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR G Y+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGRYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEAPVTWRRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTT+HLVNKE L  MKK+AIL+NCSRGPVIDEAALV+HL++NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAI+VPHIASASKWTREGMATLAALNVLG++KGYP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPVWSDPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALG 380
           +EN SPP ASPSIVN+KALG
Sbjct: 361 DENVSPPAASPSIVNAKALG 380
>dbj|BAA08411.1| hydroxypyruvate reductase [Cucurbita cv. Kurokawa Amakuri]
          Length = 381

 Score =  556 bits (1434), Expect = e-157,   Method: Composition-based stats.
 Identities = 335/381 (87%), Positives = 360/381 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MA  V +EV+NPNGKYRVVSTKPMPGTRWINLL++Q CRVEIC  KKTILSVEDI+ LIG
Sbjct: 1   MANRVQVEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDIVALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALS+AG KAFSNMAVGYNNVDV AANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEVLFSALSRAGCKAFSNMAVGYNNVDVNAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR G Y+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGHYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEVPVTWRRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTT+HLVNKE L  MKK+AIL+NCSRGPVIDEAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAI+VPHIASASKWTREGMATLAALNVLG++K YP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKQYPVWADPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGL 381
           +ENA PP ASPSIVN+KALG+
Sbjct: 361 DENAPPPAASPSIVNAKALGI 381
>gb|ABK21250.1| unknown [Picea sitchensis]
          Length = 386

 Score =  556 bits (1434), Expect = e-156,   Method: Composition-based stats.
 Identities = 312/386 (80%), Positives = 355/386 (91%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEV+NP GK+RVVSTK MPGTRWI LL D  CR+EIC  KKTIL VEDI  LIG
Sbjct: 1   MAKPISIEVWNPAGKHRVVSTKSMPGTRWIRLLTDADCRLEICTEKKTILDVEDIQALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFS L +AGG AFSNMAVGYNNVD+ AAN YGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSTLKRAGGTAFSNMAVGYNNVDLNAANTYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELA +L+++A+RR+VEAD+FMR GLY+GWLPHLFVGNLLKGQTVG+IGAGRIGSAY
Sbjct: 121 ETTAELAVALTVSASRRVVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGIIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEK++TAYG+FLK+ GE PVTWKRAS+ E+VLR+AD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKYMTAYGEFLKSQGEAPVTWKRASTAEDVLRDADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHP+LDKTTYHL+NK+RL++MKKEA+LVN SRGPVIDEAALV HLK NPMFRVGLDVFE
Sbjct: 241 SLHPILDKTTYHLINKDRLSIMKKEAVLVNASRGPVIDEAALVNHLKANPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLA+ KNA+VVPHIASASKWTREGMATLAALNVLG+VKGYP+W D N+++PFL
Sbjct: 301 DEPYMKPGLAEQKNAVVVPHIASASKWTREGMATLAALNVLGKVKGYPVWPDANKLEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           +EN++PP A PSIVN+K LGL VSKL
Sbjct: 361 DENSAPPAACPSIVNAKLLGLEVSKL 386
>ref|NP_001045589.1| Os02g0101500 [Oryza sativa (japonica cultivar-group)]
 dbj|BAD07805.1| putative hydroxypyruvate reductase [Oryza sativa Japonica Group]
 dbj|BAD08188.1| putative hydroxypyruvate reductase [Oryza sativa Japonica Group]
 dbj|BAF07503.1| Os02g0101500 [Oryza sativa (japonica cultivar-group)]
          Length = 386

 Score =  554 bits (1428), Expect = e-156,   Method: Composition-based stats.
 Identities = 328/386 (84%), Positives = 360/386 (93%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEV+NP+GKYRVVSTK MPGTRWI LL D  CR+EIC   KTILSV+DI+ LIG
Sbjct: 1   MAKPISIEVWNPSGKYRVVSTKSMPGTRWIRLLADNDCRLEICTETKTILSVDDILALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           D+CDGVIGQLTE+WGE LFSAL +AGG AFSNMAVGYNNVDVEAAN+ GIAVGNTPGVLT
Sbjct: 61  DRCDGVIGQLTEEWGEVLFSALKRAGGTAFSNMAVGYNNVDVEAANRNGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEAD+FMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMM+EGFKMNLIY+DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRA++ME+VLREAD+I
Sbjct: 181 ARMMIEGFKMNLIYYDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRAATMEDVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHL+N ERLA+MKKEA+LVN SRGPVIDE ALVEHLK NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLINPERLAIMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNA+VVPHIASASKWTREGMATLAALNVLG++KGYP+W +PN V+PFL
Sbjct: 301 DEPYMKPGLADMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNLVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
            E+A+PP A PSIVN+K LGLP SKL
Sbjct: 361 KEDATPPAACPSIVNAKQLGLPSSKL 386
>ref|XP_001784621.1| predicted protein [Physcomitrella patens subsp. patens]
 gb|EDQ50553.1| predicted protein [Physcomitrella patens subsp. patens]
          Length = 391

 Score =  511 bits (1318), Expect = e-143,   Method: Composition-based stats.
 Identities = 294/383 (76%), Positives = 338/383 (88%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MA+ ++++VYN  G  RVVSTKPMPG +WI  L   GCRVE+C   KTILSV+DI+ LIG
Sbjct: 1   MARKLAVQVYNAGGHLRVVSTKPMPGNQWIQALTSVGCRVEVCVENKTILSVDDILSLIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
            KCDGVIGQLTEDWG+ LF+AL KAGG A+SNMAVGYNNVDVEAA ++GIAVGNTPGVLT
Sbjct: 61  TKCDGVIGQLTEDWGDVLFAALKKAGGHAYSNMAVGYNNVDVEAATRHGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAA+L+L+AARR+VEAD+FMR G YEGWLP LFVGNLLKGQTVG+IGAGRIG+AY
Sbjct: 121 ETTAELAAALTLSAARRVVEADDFMRAGKYEGWLPTLFVGNLLKGQTVGIIGAGRIGTAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMN+IY+DLYQSTRLEKFVTAYG+FLK  GE PV W+RASS E+VLREAD+I
Sbjct: 181 ARMMVEGFKMNVIYYDLYQSTRLEKFVTAYGEFLKTQGEAPVHWRRASSPEDVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHL+NK+RLA+MKKEA+LVN SRGPVIDE ALVEHLK NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLINKDRLALMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGL D  NA+VVPHIASASKWTREGMATLAA NV  ++KGYP+W + N ++PFL
Sbjct: 301 DEPYMKPGLGDLPNAVVVPHIASASKWTREGMATLAAQNVAAKLKGYPVWPNSNNIEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPV 383
           +E+   P A+PSIVN+KALGLP 
Sbjct: 361 DESKPAPAAAPSIVNAKALGLPT 383
>ref|XP_001752353.1| predicted protein [Physcomitrella patens subsp. patens]
 gb|EDQ83086.1| predicted protein [Physcomitrella patens subsp. patens]
          Length = 385

 Score =  502 bits (1293), Expect = e-140,   Method: Composition-based stats.
 Identities = 283/380 (74%), Positives = 335/380 (88%), Gaps = 1/380 (0%)

Query: 2   AKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGD 61
           AK ++++V+N  G  RV+STKPMPGT+WI  L   GCRVE+C   K ILS +DI+ LIG+
Sbjct: 3   AKQLAVQVHNAGGTLRVLSTKPMPGTQWIKTLTSVGCRVEVCTEPKVILSTDDIVSLIGN 62

Query: 62  KCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTE 121
           KCDGVIGQLTEDWG+TLF AL KAGG A+SNMAVGYNNVDV+AA ++GI+VGNTPGVLTE
Sbjct: 63  KCDGVIGQLTEDWGDTLFGALKKAGGHAYSNMAVGYNNVDVDAATRHGISVGNTPGVLTE 122

Query: 122 TTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYA 181
           TTAELAA+L+LAAARR+VEAD+FMR G YEGWLP LFVGNLLKGQTVG+IGAGRIG+AYA
Sbjct: 123 TTAELAAALTLAAARRVVEADDFMRAGKYEGWLPTLFVGNLLKGQTVGIIGAGRIGTAYA 182

Query: 182 RMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLIS 241
           RMMVEGFKMN+IY+DLYQ+TRLEKFV+AYGQFL++ GE PV W+RASS E+VL+EAD++S
Sbjct: 183 RMMVEGFKMNVIYYDLYQATRLEKFVSAYGQFLESQGETPVHWRRASSPEDVLKEADVVS 242

Query: 242 LHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEE 301
           LHPVLDKTTYHL+NKERLA+MKK+A+LVN SRGPV+DE ALVEHLK NPMFRVGLDVFE+
Sbjct: 243 LHPVLDKTTYHLINKERLALMKKDAVLVNASRGPVVDETALVEHLKANPMFRVGLDVFED 302

Query: 302 EPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
           EP+MKPGL +  NA+VVPHIASASKWTREGMATLAA NV  ++KG+P+W  PN V+PFL+
Sbjct: 303 EPYMKPGLGELSNAVVVPHIASASKWTREGMATLAAQNVAAKLKGWPVWSSPN-VEPFLD 361

Query: 362 ENASPPNASPSIVNSKALGL 381
           E    P A+PSI+N+KAL L
Sbjct: 362 EIKPAPKAAPSIINAKALCL 381
>gb|EAZ21390.1| hypothetical protein OsJ_004873 [Oryza sativa (japonica
           cultivar-group)]
          Length = 380

 Score =  488 bits (1258), Expect = e-136,   Method: Composition-based stats.
 Identities = 307/408 (75%), Positives = 336/408 (82%), Gaps = 50/408 (12%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEV+NP+GKYRVVSTK MPGTRWI LL D  CR+E                   
Sbjct: 1   MAKPISIEVWNPSGKYRVVSTKSMPGTRWIRLLADNDCRLE------------------- 41

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTP---- 116
                    LTE+WGE LFSAL +AGG AFSNMAVGYNNVDVEAAN+ GIAVGNTP    
Sbjct: 42  ---------LTEEWGEVLFSALKRAGGTAFSNMAVGYNNVDVEAANRNGIAVGNTPVSSA 92

Query: 117 -------------GVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLL 163
                        GVLTETTAELAASLSLAAARRIVEAD+FMR GLY+GWLPHLFVGNLL
Sbjct: 93  ALCFLISRLSYWMGVLTETTAELAASLSLAAARRIVEADQFMRAGLYDGWLPHLFVGNLL 152

Query: 164 KGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 223
           KGQTVGVIGAGRIGSAYARMM+EGFKMNLIY+DLYQSTRLEKFVTAYGQFLKANGEQPVT
Sbjct: 153 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYYDLYQSTRLEKFVTAYGQFLKANGEQPVT 212

Query: 224 WKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALV 283
           WKRA++ME+VLREAD+ISLHPVLDKTTYHL+N ERLA+MKKEA+LVN SRGPVIDE ALV
Sbjct: 213 WKRAATMEDVLREADVISLHPVLDKTTYHLINPERLAIMKKEAVLVNASRGPVIDEVALV 272

Query: 284 EHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASK-----WTREGMATLAAL 338
           EHLK NPMFRVGLDVFE+EP+MKPGLAD KNA+VVPHIASASK     WTREGMATLAAL
Sbjct: 273 EHLKANPMFRVGLDVFEDEPYMKPGLADMKNAVVVPHIASASKSPNHQWTREGMATLAAL 332

Query: 339 NVLGRVKGYPIWHDPNRVDPFLNENASPPNASPSIVNSKALGLPVSKL 386
           NVLG++KGYP+W +PN V+PFL E+A+PP A PSIVN+K LGLP SKL
Sbjct: 333 NVLGKIKGYPVWGNPNLVEPFLKEDATPPAACPSIVNAKQLGLPSSKL 380
>gb|EAY84074.1| hypothetical protein OsI_005307 [Oryza sativa (indica
           cultivar-group)]
          Length = 399

 Score =  484 bits (1247), Expect = e-135,   Method: Composition-based stats.
 Identities = 303/400 (75%), Positives = 332/400 (83%), Gaps = 45/400 (11%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEV+NP+GKYRVVSTK MPGTRWI LL D  CR+E                   
Sbjct: 1   MAKPISIEVWNPSGKYRVVSTKSMPGTRWIRLLADNDCRLE------------------- 41

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTP---- 116
                    LTE+WGE LFSAL +AGG AFSNMAVGYNNVDVEAAN+ GIAVGNTP    
Sbjct: 42  ---------LTEEWGEVLFSALKRAGGTAFSNMAVGYNNVDVEAANRNGIAVGNTPVSSA 92

Query: 117 -------------GVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLL 163
                        GVLTETTAELAASLSLAAARRIVEAD+FMR GLY+GWLPHLFVGNLL
Sbjct: 93  ALCFLISRLSYWMGVLTETTAELAASLSLAAARRIVEADQFMRAGLYDGWLPHLFVGNLL 152

Query: 164 KGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVT 223
           KGQTVGVIGAGRIGSAYARMM+EGFKMNLIY+DLYQSTRLEKFVTAYGQFLKANGEQPVT
Sbjct: 153 KGQTVGVIGAGRIGSAYARMMIEGFKMNLIYYDLYQSTRLEKFVTAYGQFLKANGEQPVT 212

Query: 224 WKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALV 283
           WKRA++ME+VLREAD+ISLHPVLDKTTYHL+N ERLA+MKKEA+LVN SRGPVIDE ALV
Sbjct: 213 WKRAATMEDVLREADVISLHPVLDKTTYHLINPERLAIMKKEAVLVNASRGPVIDEVALV 272

Query: 284 EHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGR 343
           EHLK NPMFRVGLDVFE+EP+MKPGLAD KNA+VVPHIASASKWTREGMATLAALNVLG+
Sbjct: 273 EHLKANPMFRVGLDVFEDEPYMKPGLADMKNAVVVPHIASASKWTREGMATLAALNVLGK 332

Query: 344 VKGYPIWHDPNRVDPFLNENASPPNASPSIVNSKALGLPV 383
           +KGYP+W +PN V+PFL E+A+PP A PSIVN+K LG P 
Sbjct: 333 IKGYPVWGNPNLVEPFLKEDATPPAACPSIVNAKQLGRPA 372
>ref|ZP_01666395.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermosinus carboxydivorans Nor1]
 gb|EAX47745.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermosinus carboxydivorans Nor1]
          Length = 327

 Score =  462 bits (1191), Expect = e-128,   Method: Composition-based stats.
 Identities = 133/345 (38%), Positives = 196/345 (56%), Gaps = 25/345 (7%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
            ++ V  T+ +P T    L   Q C VE+ + +  +L+ ++++  +  + D V+  LT+ 
Sbjct: 2   AQFNVYVTRRIPDTALDVLR--QRCNVEV-NPEDRVLTRDELLAKVTGR-DAVLCLLTDT 57

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
             + + +A  K   + F+N AVGYNN+DV AA K GI + NTP VLT  TA++A +L  A
Sbjct: 58  IDDAVLAAAGK-QCRIFANYAVGYNNIDVAAATKRGIFISNTPDVLTAATADMAWALLFA 116

Query: 134 AARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
            ARR+VE D+F R G + GW P L +G  + G+TVG+IGAGRIG+A+AR   +GF M ++
Sbjct: 117 VARRVVEGDKFTRAGKFHGWGPLLMLGQEVTGKTVGIIGAGRIGAAFARR-AKGFDMKIL 175

Query: 194 YFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHL 253
           Y    +    E+                 T       + +LREAD ISLH  L   TYHL
Sbjct: 176 YTGRSRKPDFERE----------------TGATYVDFDTLLREADFISLHVPLTPETYHL 219

Query: 254 VNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTK 313
           + +  L +MK  AIL+N +RGPV+DE ALV  L+   ++  GLDVFE EP +  GLA+  
Sbjct: 220 IGERELKLMKPTAILINTARGPVVDEKALVAALRRGEIWGAGLDVFENEPALAEGLAELD 279

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDP 358
           N ++ PH+ SA+  TR  M  +A  N+L  + G      PN ++P
Sbjct: 280 NVVIPPHLGSATLETRTKMGLVAVENILAALDGR---MPPNCLNP 321
>ref|YP_001410651.1| Glyoxylate reductase [Fervidobacterium nodosum Rt17-B1]
 gb|ABS60994.1| Glyoxylate reductase [Fervidobacterium nodosum Rt17-B1]
          Length = 317

 Score =  461 bits (1187), Expect = e-128,   Method: Composition-based stats.
 Identities = 145/342 (42%), Positives = 205/342 (59%), Gaps = 27/342 (7%)

Query: 16  YRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWG 75
            RV  T  +P  + IN+L  +   V++   ++  LS E++I    +  D ++ QL +   
Sbjct: 1   MRVFVTYAIP-EKGINMLK-ERFEVDVYTGEE-FLSKEEMIKR-AEYADAIVTQLRDPID 56

Query: 76  ETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAA 135
           +    +L KA  K  +N AVGYNN+D+EAA + GI V NTPGVLTE TA++A +L LA A
Sbjct: 57  KEFIYSLKKA--KIIANYAVGYNNIDIEAAKERGIYVTNTPGVLTEATADIAFALILAVA 114

Query: 136 RRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYF 195
           RRIVE+D+F+R G + GW P LF+G  L G+T+GVIG GRIG A AR    GF MN++Y+
Sbjct: 115 RRIVESDKFVREGKFVGWKPKLFLGYDLYGKTLGVIGMGRIGQAVARR-ALGFGMNIVYY 173

Query: 196 DLYQSTR-LEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
           +  +    +EK   A                +  +++E++  +D ISLH  L K TYHL+
Sbjct: 174 NRNRLPEEIEKQYNA----------------KYVNIDELVEISDYISLHTPLTKETYHLI 217

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKN 314
           NKER+A MK  AILVN +RGPV+DE AL E LKE  +   G DV+E EP + PGL    N
Sbjct: 218 NKERIAKMKPNAILVNTARGPVVDEQALYEALKERRIAGAGFDVYENEPVLTPGLEKLDN 277

Query: 315 AIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRV 356
            +++PHI SA+  TR+ M+ + A+NV+  + G       N V
Sbjct: 278 VVLLPHIGSATYETRDKMSEIVAINVMEALDGK---RPSNCV 316
>ref|YP_001471315.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Thermotoga lettingae TMO]
 gb|ABV34251.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Thermotoga lettingae TMO]
          Length = 327

 Score =  460 bits (1184), Expect = e-127,   Method: Composition-based stats.
 Identities = 139/345 (40%), Positives = 199/345 (57%), Gaps = 26/345 (7%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
            K +V  T  +P       ++ Q C ++I +    +L  + +ID +    DG++  L + 
Sbjct: 2   KKPKVFVTAQIPDEGLK--MISQHCEMQIGNY-DGVLPKDVLIDKVKG-VDGILCLLADV 57

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
             + +  A  K   K  +N AVGYNN+D+E A K GI V NTPGVLTETTA+LA +L ++
Sbjct: 58  IDKDVMEAAGK-QLKVIANYAVGYNNIDIEEATKRGIMVTNTPGVLTETTADLAWALMMS 116

Query: 134 AARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
            ARRIVE+D+F+R G + GW P L +G  + G T+GV+G GRIG A AR    GF M ++
Sbjct: 117 IARRIVESDKFVREGKFNGWQPMLMLGTDIYGATLGVVGFGRIGQAVARR-ASGFNMRVL 175

Query: 194 YFDLYQSTR-LEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYH 252
           Y+   ++   +EK + A                    +  +LRE+D ++LH  L K TYH
Sbjct: 176 YYSRKRAPEDVEKQLNA----------------SFVDLSTLLRESDFVTLHLPLTKETYH 219

Query: 253 LVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADT 312
           L+ +E L MMKKEA L+N +RGPVIDE ALV+ LK   +    LDVFE+EP ++P L + 
Sbjct: 220 LIGEEELRMMKKEAYLINTARGPVIDEKALVKALKNKWIRGAALDVFEKEPQIEPELLEL 279

Query: 313 KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVD 357
            N I+ PHI SAS  TR  M+ +AA N++  + G      PN V+
Sbjct: 280 DNVILTPHIGSASYTTRTKMSVMAAENLVKALYGEI---PPNLVN 321
>ref|ZP_01368724.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Desulfitobacterium hafniense DCB-2]
 gb|EAT52306.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Desulfitobacterium hafniense DCB-2]
          Length = 334

 Score =  457 bits (1178), Expect = e-127,   Method: Composition-based stats.
 Identities = 120/345 (34%), Positives = 186/345 (53%), Gaps = 26/345 (7%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K RV  T+ +P    I  L+++ C V++   + T +    +++    + DG+   LTE  
Sbjct: 8   KPRVFITRKIPED--ILTLIEEVCEVKVWPEEDTPIPRS-VLEQEIREVDGLYCLLTETI 64

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
             +L         K  SNMAVGYNN+D+EAA +  I V NTPGVLTETTA+L  +L +  
Sbjct: 65  DASLLDLGKNL--KVVSNMAVGYNNIDIEAATQRNILVTNTPGVLTETTADLTFALLMMT 122

Query: 135 ARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIY 194
           ARR+ E+ +++R G ++ W P L  G  + G T+G++G GRIG A  +   +GF M +IY
Sbjct: 123 ARRMEESSQYLRQGHWKTWSPMLLAGQDIFGATLGIVGMGRIGEALVKR-AKGFDMKIIY 181

Query: 195 FDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
           ++      LE+ +                     S++E+L+EAD + +       T +L+
Sbjct: 182 YNRTPKPELEESLG----------------IEYRSLDELLQEADFVCILTPYTPETRNLI 225

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPF-MKPGLADTK 313
            K  L +MK  +IL+N +RG +++E  L E L +  ++  GLDVFE+EP      L    
Sbjct: 226 GKRELELMKPTSILINTARGGIVNEEDLYEALAQQKIYAAGLDVFEQEPLPTDHPLLTLT 285

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDP 358
           N + +PHI SA+  TR  MA LAA N+L  ++G      P+ V+P
Sbjct: 286 NCVALPHIGSATVKTRREMARLAAQNLLAYLQGQ---RPPHCVNP 327
>ref|NP_578048.1| glyoxylate reductase [Pyrococcus furiosus DSM 3638]
 sp|Q8U3Y2|GYAR_PYRFU Glyoxylate reductase (Glycolate reductase)
 gb|AAL80443.1| putative phosphoglycerate dehydrogenase [Pyrococcus furiosus DSM
           3638]
          Length = 336

 Score =  456 bits (1174), Expect = e-126,   Method: Composition-based stats.
 Identities = 125/356 (35%), Positives = 194/356 (54%), Gaps = 30/356 (8%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K +V  T+ +P    IN+L ++         ++  +  E +++ + D  D ++  L+E  
Sbjct: 2   KPKVFITRAIP-ENGINMLEEEF--EVEVWEEEREIPREKLLEKVKD-VDALVTMLSERI 57

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
            + +F    +   +  +N AVGY+N+DVE A + GI V NTP VLT  TA+ A +L LA 
Sbjct: 58  DQEVFENAPRL--RIVANYAVGYDNIDVEEATRRGIYVTNTPDVLTNATADHAFALLLAT 115

Query: 135 ARRIVEADEFMRGGLYE----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKM 190
           AR +V+ D+F+R G ++     W P  F+G  L G+T+G++G GRIG A AR   +GF M
Sbjct: 116 ARHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARR-AKGFNM 174

Query: 191 NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTT 250
            ++Y+   + ++ EK + A                    +EEVL+E+D + L   L K T
Sbjct: 175 RILYYSRTRKSQAEKELGA----------------EYRPLEEVLKESDFVILAVPLTKET 218

Query: 251 YHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLA 310
            +++N+ERL +MK  AILVN +RG V+D  AL++ LKE  +   GLDVFEEEP+    L 
Sbjct: 219 MYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPYYNEELF 278

Query: 311 DTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASP 366
              N ++ PHI SA+   RE MA L A N++   +G      P  V+  + +   P
Sbjct: 279 SLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRGEI---PPTLVNKEVIKIRKP 331
>gb|ABD97861.1| NADH-dependent hydroxypyruvate reductase [Pachysandra terminalis]
          Length = 303

 Score =  454 bits (1169), Expect = e-126,   Method: Composition-based stats.
 Identities = 269/303 (88%), Positives = 293/303 (96%)

Query: 84  KAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADE 143
           +AGG+AFSNMAVGYNNVDV AANKYG+AVGNTPGVLTETTAELAASLS++AARRIVEADE
Sbjct: 1   RAGGRAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLTETTAELAASLSVSAARRIVEADE 60

Query: 144 FMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRL 203
           FMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM+EGFKMNLIY+DLYQ+TRL
Sbjct: 61  FMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMIEGFKMNLIYYDLYQATRL 120

Query: 204 EKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMK 263
           EKFVTAYG+FLKANGE PVTWKRASSMEEVLREAD+ISLHP+LDKTTYHL+NKERL+MMK
Sbjct: 121 EKFVTAYGEFLKANGEPPVTWKRASSMEEVLREADVISLHPILDKTTYHLINKERLSMMK 180

Query: 264 KEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIAS 323
           KEAILVNCSRGPV+DE ALVEHLKENPMFRVGLDVFE+EP+MKPGLAD KNAIVVPHIAS
Sbjct: 181 KEAILVNCSRGPVVDEVALVEHLKENPMFRVGLDVFEDEPYMKPGLADMKNAIVVPHIAS 240

Query: 324 ASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASPPNASPSIVNSKALGLPV 383
           ASKWTREGMATLAALNVLG++KGYP+W DPNRV+PFLN+N+ PP ASPSIVN+KALGL  
Sbjct: 241 ASKWTREGMATLAALNVLGKIKGYPVWSDPNRVEPFLNKNSPPPAASPSIVNAKALGLTA 300

Query: 384 SKL 386
           SKL
Sbjct: 301 SKL 303
>ref|NP_422516.1| 2-hydroxyacid dehydrogenase [Caulobacter crescentus CB15]
 gb|AAK25684.1| D-isomer specific 2-hydroxyacid dehydrogenases family protein
           [Caulobacter crescentus CB15]
          Length = 344

 Score =  452 bits (1165), Expect = e-125,   Method: Composition-based stats.
 Identities = 107/348 (30%), Positives = 178/348 (51%), Gaps = 23/348 (6%)

Query: 13  NGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTE 72
             K +V+ T+ +P    +   + +    E+ ++    ++ ++++D +  + D ++  +T+
Sbjct: 19  ARKLKVIVTRKLPDP--VETRMCELFDTEL-NVSDKPMTADELVDAMS-RADVLVPTITD 74

Query: 73  DWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSL 132
                L S  S    K  +N   G +N+DV  AN  GI V NTPGVLTE TA+L  +L +
Sbjct: 75  RIDSRLLSR-SGDRLKLIANFGAGVDNIDVATANARGIIVTNTPGVLTEDTADLTMTLIM 133

Query: 133 AAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNL 192
           AA+RRIVE  E ++ G + GW P   +G  L G+ +G+IG GRIG A AR   + F M +
Sbjct: 134 AASRRIVEGAEVVKAGGFHGWSPTWMMGRRLWGKRLGIIGMGRIGQAVARR-AKAFGMQV 192

Query: 193 IYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYH 252
            Y +                 +     + +      S++++L   D +S++      TYH
Sbjct: 193 HYHNRKP--------------VSPRIAEELGCTYWESLDQMLARMDFVSVNCPHTPATYH 238

Query: 253 LVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADT 312
           L++  RL +++  A++VN +RG VIDE AL   L +  +   GLDV+E EP + P L   
Sbjct: 239 LLSARRLKLLRPHAVVVNTARGEVIDEGALANMLAKGEIAGAGLDVYEHEPAINPKLLKL 298

Query: 313 KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
            N +++PH+ SA+   R  M     +NV   + G+     P+RV P +
Sbjct: 299 PNVVLLPHMGSATVEGRIDMGEKVIVNVKTFMDGH---RPPDRVIPAM 343
>ref|YP_517906.1| hypothetical protein DSY1673 [Desulfitobacterium hafniense Y51]
 dbj|BAE83462.1| hypothetical protein [Desulfitobacterium hafniense Y51]
          Length = 334

 Score =  451 bits (1161), Expect = e-125,   Method: Composition-based stats.
 Identities = 118/345 (34%), Positives = 186/345 (53%), Gaps = 26/345 (7%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K RV  T+ +P    I  L+++ C V++   + T +    +++    + DG+   LTE  
Sbjct: 8   KPRVFITRKIPED--ILTLIEEVCEVKVWPEEDTPIPRS-VLEQEIREVDGLYCLLTETI 64

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
             +L         K  SNMAVGYNN+D+EAA +  I V NTPGVLTETTA+L  +L +  
Sbjct: 65  DASLLDLGKNL--KVVSNMAVGYNNIDIEAATQRNILVTNTPGVLTETTADLTFALLMMT 122

Query: 135 ARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIY 194
           ARR+ E+ +++R G ++ W P L  G  + G T+G++G GRIG A  +   +GF M +IY
Sbjct: 123 ARRMEESSQYLRQGHWKTWSPMLLAGQDIFGATLGIVGMGRIGEALVKR-AKGFDMKIIY 181

Query: 195 FDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
           ++      LE+ +    +                 ++E+L+EAD + +       T +L+
Sbjct: 182 YNRTPKPELEESLGIEYRL----------------LDELLQEADFVCILTPYTPETRNLI 225

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPF-MKPGLADTK 313
            K  L +MK  +IL+N +RG +++E  L E L +  ++  GLDVF++EP      L    
Sbjct: 226 GKRELELMKPTSILINTARGGIVNEEDLYEALAQQQIYAAGLDVFDQEPLPTDHPLLTLT 285

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDP 358
           N + +PHI SA+  TR  MA LAA N+L  ++G      P+ V+P
Sbjct: 286 NCVALPHIGSATIKTRREMARLAAQNLLTYLQGQ---RPPHCVNP 327
>ref|XP_001691480.1| hydroxypyruvate reductase [Chlamydomonas reinhardtii]
 gb|EDP05213.1| hydroxypyruvate reductase [Chlamydomonas reinhardtii]
          Length = 418

 Score =  449 bits (1157), Expect = e-124,   Method: Composition-based stats.
 Identities = 239/379 (63%), Positives = 288/379 (75%)

Query: 5   VSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCD 64
           V +EV+N  G  RVV TK +PG RW+  L++ GCRVE+      ILS   I  LIG KCD
Sbjct: 37  VPVEVHNEGGSKRVVVTKTLPGERWLQFLINAGCRVEVSQHPDIILSNATIKQLIGTKCD 96

Query: 65  GVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTA 124
           GVIGQLTEDWG  LF AL +AGGKA+SN AVGYNNV V+ A K GI VGNTPGVLTETTA
Sbjct: 97  GVIGQLTEDWGAELFEALKQAGGKAYSNYAVGYNNVKVDEATKRGIPVGNTPGVLTETTA 156

Query: 125 ELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMM 184
           ELAA+L+LAAARR+ EAD FMR G Y+GWLP+LFVG LL+ +TVG+IGAGRIG+AYARMM
Sbjct: 157 ELAAALTLAAARRVPEADVFMRAGKYKGWLPNLFVGQLLQNKTVGIIGAGRIGAAYARMM 216

Query: 185 VEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHP 244
           VEG KMNL+YFD Y + +LE+++  YG+ L+  GE PV  KR  ++EEVL+EAD++SLH 
Sbjct: 217 VEGHKMNLVYFDPYPNKQLEEYIRLYGELLRHRGEPPVACKRVETVEEVLKEADVVSLHC 276

Query: 245 VLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPF 304
            LD +T HL+N +RLA+MK  A+LVN +RGP IDEAALV HLK NP FR GLDVFE+EP 
Sbjct: 277 NLDASTRHLINSQRLALMKPTAVLVNAARGPCIDEAALVAHLKANPEFRCGLDVFEDEPA 336

Query: 305 MKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENA 364
           MKPGLAD  NA++VPHIASAS WTR GMATLAA NV G + GYP+W+  + +       A
Sbjct: 337 MKPGLADCANAVIVPHIASASLWTRSGMATLAAANVAGILSGYPVWNKQDILGFVDKPLA 396

Query: 365 SPPNASPSIVNSKALGLPV 383
           + P A+PSIVN+K L L  
Sbjct: 397 AAPLAAPSIVNAKELKLKT 415
>ref|ZP_03856830.1| lactate dehydrogenase-like oxidoreductase [Thermobaculum terrenum
           ATCC BAA-798]
 gb|EEI02352.1| lactate dehydrogenase-like oxidoreductase [Thermobaculum terrenum
           ATCC BAA-798]
          Length = 319

 Score =  448 bits (1154), Expect = e-124,   Method: Composition-based stats.
 Identities = 133/343 (38%), Positives = 191/343 (55%), Gaps = 30/343 (8%)

Query: 16  YRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWG 75
           YRV  T+ +P    + LL D G  ++I        S E++   I  + D +I  LT+   
Sbjct: 2   YRVYITRKIP-EAGLRLLKDHGFELDIWPG-DLPPSKEELKRGIS-QADAMISLLTDKID 58

Query: 76  ETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAA 135
           E + S       K  +N AVGY+N+D+EAA K GI V NTP VLTETTA+LA +L L+ A
Sbjct: 59  EEVISNARNL--KVIANYAVGYDNIDLEAATKAGIVVTNTPDVLTETTADLAWALMLSVA 116

Query: 136 RRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYF 195
           RR++E    ++ G +  W P L +G  + G T+G++G GRIG A AR    GF+M ++Y 
Sbjct: 117 RRLIEGVSHVKDGKWRTWEPQLLLGQDVYGATLGIVGMGRIGQAVARR-AIGFQMKVLYT 175

Query: 196 DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVN 255
              + T ++                     +  S++E+L ++D ISLH  L K T H++N
Sbjct: 176 SRSEKTGID--------------------AQKVSLDELLAQSDFISLHTPLTKETRHMIN 215

Query: 256 KERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFM-KPGLADTKN 314
           K  L  MK  AIL+N +RGP++D AALVE L+E  +   GLDV + EP      L    N
Sbjct: 216 KSTLKRMKPTAILINTARGPLVDTAALVEALREGQIAGAGLDVTDPEPLPRNHPLLYLPN 275

Query: 315 AIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVD 357
            IVVPHI SAS+ TR+ M+ +AA NV+  ++G      PN+V+
Sbjct: 276 CIVVPHIGSASQRTRDLMSEIAARNVIAVLEG---SQAPNQVN 315
>ref|YP_430795.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Moorella thermoacetica ATCC 39073]
 gb|ABC20252.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Moorella thermoacetica ATCC 39073]
          Length = 329

 Score =  447 bits (1151), Expect = e-124,   Method: Composition-based stats.
 Identities = 144/348 (41%), Positives = 215/348 (61%), Gaps = 26/348 (7%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
            K+ V  T+ +P       L+ + C +EI + +  +L+  ++++ +  + DG++  LT+ 
Sbjct: 2   SKWNVYVTRLVPQPALD--LLAEYCDLEI-NPEDRVLTRAELLEKVRGR-DGILCLLTDI 57

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
             + +F+A   A  K F+N+AVG+NNVD+EAA ++GI + NTPGVLTE TA++A +L  A
Sbjct: 58  LDDEVFTAAKGA--KIFANLAVGFNNVDLEAATRHGIMITNTPGVLTEATADMAWALLFA 115

Query: 134 AARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
            ARR+VE D+F R G Y+GW P L +G  + G+T+GVIGAGRIG+A+AR    GF M ++
Sbjct: 116 VARRVVEGDKFTRAGKYKGWGPLLMLGQEITGKTLGVIGAGRIGTAFARK-ARGFDMKVL 174

Query: 194 YFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHL 253
           Y D+  S   E+                 T  +    E +L+EAD +SLH  L  +T HL
Sbjct: 175 YHDVQPSKAFEE----------------ATGGQFVDKETLLKEADFVSLHVPLMPSTTHL 218

Query: 254 VNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTK 313
           ++   L +MKK AIL+N SRGPV+DE ALV+ L+E  ++  GLDVFE EP + PGLAD +
Sbjct: 219 ISTPELKLMKKTAILINTSRGPVVDEKALVKALREKEIWGAGLDVFENEPELAPGLADLE 278

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
           N ++ PHIASA+  TR  MA +AA N+L  ++G      P  ++P + 
Sbjct: 279 NVVLCPHIASATWETRTNMALMAANNLLAALRGE---LPPQCLNPEVY 323
>ref|YP_001686676.1| Glyoxylate reductase [Caulobacter sp. K31]
 gb|ABZ74178.1| Glyoxylate reductase [Caulobacter sp. K31]
          Length = 328

 Score =  447 bits (1150), Expect = e-124,   Method: Composition-based stats.
 Identities = 109/351 (31%), Positives = 177/351 (50%), Gaps = 29/351 (8%)

Query: 13  NGKYRVVSTKPMPG---TRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQ 69
             K +V+ T+ +P    TR   L   Q       ++    L+ +++++ + ++ D ++  
Sbjct: 3   ARKLKVIVTRKLPDPVETRMCELFDTQ------LNVTDKPLTADELVEAM-NEADVLVPT 55

Query: 70  LTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAAS 129
           +T+     L S       K  +N   G +N+DV  AN  GI V NTPGVLTE TA+L  +
Sbjct: 56  ITDRIDSRLLSRAGD-RLKLIANFGAGVDNIDVATANARGIIVTNTPGVLTEDTADLTMT 114

Query: 130 LSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFK 189
           L +AA+RR+VE  E ++ G + GW P   +G  L G+ +G+IG GRIG A AR   + F 
Sbjct: 115 LIMAASRRVVEGAEVVKAGGFHGWSPTWMLGRRLWGKRLGIIGMGRIGQAVARR-AKAFG 173

Query: 190 MNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKT 249
           M + Y +                 +     + +      S++++L   D+IS++      
Sbjct: 174 MQVHYHNRKP--------------VSPRIAEELGCTYWESLDQMLARMDIISVNCPHTPA 219

Query: 250 TYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGL 309
           TYHL++  RL +++ + I+VN +RG VIDE AL   L    +   GLDV+E EP + P L
Sbjct: 220 TYHLLSARRLKLLRPQTIIVNTARGEVIDEGALANMLARGEIAGAGLDVYEHEPAINPKL 279

Query: 310 ADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
               N +++PH+ SA+   R  M     +NV   + G+     P+RV P +
Sbjct: 280 LKLPNVVLLPHMGSATVEGRIDMGEKVIVNVKTFMDGH---RPPDRVIPSM 327
>ref|YP_001737977.1| Glyoxylate reductase [Candidatus Korarchaeum cryptofilum OPF8]
 gb|ACB08294.1| Glyoxylate reductase [Candidatus Korarchaeum cryptofilum OPF8]
          Length = 332

 Score =  447 bits (1150), Expect = e-124,   Method: Composition-based stats.
 Identities = 130/354 (36%), Positives = 199/354 (56%), Gaps = 28/354 (7%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K RV  T+ +P      +  ++   +++    +   S + II+ + D CD ++  LT+  
Sbjct: 2   KPRVFVTREIPERGLSKI--EEHFELDLW-KDEAPPSKKVIIERVKD-CDALVSLLTDPI 57

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
              +F A  K   +  +  AVGY+N+DV+ A K GI V NTPGVLTETTA+ A +L +AA
Sbjct: 58  DAEVFEAAPKL--RIVAQYAVGYDNIDVKEATKRGIYVTNTPGVLTETTADFAFALLMAA 115

Query: 135 ARRIVEADEFMRGGLYE-GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
           ARR+VEAD ++R G ++  W P + +G  + G+T+G++G GRIG+A AR   +GF M ++
Sbjct: 116 ARRVVEADRYVREGKWKVAWHPMMMLGYDVYGRTLGIVGMGRIGAAVARR-AKGFGMRIL 174

Query: 194 YFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHL 253
           Y+D  +    EK +                      +E++L E+D +SLH  L + TYH+
Sbjct: 175 YYDSIRREDFEKELGV----------------EYVPLEKLLEESDFVSLHVPLTEETYHM 218

Query: 254 VNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPF-MKPGLADT 312
           + +E+L  MK+ AILVN SRG V+D+ AL + LKE  +   GLDVFE+EP      L   
Sbjct: 219 IGEEQLRRMKRTAILVNTSRGKVVDQKALYKALKEGWIAGAGLDVFEQEPIPPDDPLLKL 278

Query: 313 KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASP 366
           +N ++ PH ASAS  TR  MA + A N++   +G      PN V+  + +   P
Sbjct: 279 ENVVLAPHAASASHETRSRMAEMVAENLIAFKRGEI---PPNLVNQEVVKVRPP 329
>ref|YP_183096.1| glyoxylate reductase [Thermococcus kodakarensis KOD1]
 sp|Q5JEZ2|GYAR_PYRKO Glyoxylate reductase (Glycolate reductase)
 dbj|BAD84872.1| glyoxylate reductase [Thermococcus kodakarensis KOD1]
          Length = 333

 Score =  443 bits (1141), Expect = e-123,   Method: Composition-based stats.
 Identities = 130/356 (36%), Positives = 195/356 (54%), Gaps = 30/356 (8%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           + +V  T+ +P    I +L  +   VE+   ++ I   E ++  + D  D ++  L+E  
Sbjct: 2   RPKVFITRAIP-ENGIEMLK-EHFEVEVWPEEREIP-REVLLKKVRD-VDALVTMLSERI 57

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
              +F A  +   +  +N AVGY+N+DVE A + GI V NTP VLT+ TA+ A +L LA 
Sbjct: 58  DSEVFDAAPRL--RIVANYAVGYDNIDVEEATRRGIYVTNTPDVLTDATADFAWTLLLAT 115

Query: 135 ARRIVEADEFMRGGLYE----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKM 190
           ARR++EAD F R G ++     W P  F+G  + G+T+G++G GRIG A AR    GF M
Sbjct: 116 ARRLIEADHFTRSGEWKRRGIAWHPRWFLGYDVYGKTIGIVGFGRIGQAVARR-ARGFGM 174

Query: 191 NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTT 250
            ++Y+   +    EK + A                   S+E++LRE+D + L   L K T
Sbjct: 175 RILYYSRSRKPEAEKELGA----------------EFRSLEDLLRESDFVVLAVPLTKET 218

Query: 251 YHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLA 310
            +++N+ERL +MKK AILVN +RG V+D  AL++ LKE  +   GLDV+EEEP+    L 
Sbjct: 219 QYMINEERLRLMKKTAILVNIARGKVVDTKALMKALKEGWIAGAGLDVYEEEPYYNEELF 278

Query: 311 DTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASP 366
             KN ++ PHI SA+   REGMA L A N++    G      P  V+  + +   P
Sbjct: 279 SLKNVVLAPHIGSATYGAREGMAELVARNLIAFKNGE---VPPTLVNKEVVKVRKP 331
>ref|YP_419558.1| Lactate dehydrogenase and related dehydrogenase [Magnetospirillum
           magneticum AMB-1]
 dbj|BAE48999.1| Lactate dehydrogenase and related dehydrogenase [Magnetospirillum
           magneticum AMB-1]
          Length = 358

 Score =  443 bits (1141), Expect = e-122,   Method: Composition-based stats.
 Identities = 99/349 (28%), Positives = 175/349 (50%), Gaps = 29/349 (8%)

Query: 12  PNGKYRVVSTKPMPG---TRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIG 68
           P+ K  VV ++ +P    TR + L   +       ++    ++  ++I+ +    D ++ 
Sbjct: 32  PSKKPVVVVSRKLPDVIETRMMELFDTR------LNVDDHPMTKTELIEAVK-IADVLVP 84

Query: 69  QLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAA 128
            +T+     + S       K  +N   G +++D+  A + GI V NTPGVLTE TA++A 
Sbjct: 85  TVTDRIDAGILSQA-GPNLKLVANFGTGVDHIDLATARQRGITVTNTPGVLTEDTADMAM 143

Query: 129 SLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGF 188
           +L ++  RRI E +  +R G ++GW P   +G+ + G+ +G+IG GRIG A AR   + F
Sbjct: 144 ALIMSVPRRIAEGERLIRSGDWKGWSPTFMLGHRIWGKRLGIIGMGRIGQAVARR-AKAF 202

Query: 189 KMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDK 248
            M++ Y +  +              +  + E  +      S++++L   D++++H     
Sbjct: 203 GMSIHYHNRKR--------------VHPDIETELEATYWESLDQMLARMDVVTVHCPHTP 248

Query: 249 TTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPG 308
            T+HL++  RL ++ K A +VN +RG ++DE AL   L    +   GLDVFE EP + P 
Sbjct: 249 ATFHLLSARRLELLPKHAYVVNTARGEIVDENALTRMLIRGDLAGAGLDVFEHEPAVNPK 308

Query: 309 LADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVD 357
           L    N +++PH+ SA+   R  M     +N+     G+     P+RV 
Sbjct: 309 LLALDNVVLLPHLGSATIEGRVDMGEKVLVNIKTFADGH---QPPDRVL 354
>ref|ZP_02913953.1| Glyoxylate reductase [Geobacillus sp. WCH70]
 gb|EDT34934.1| Glyoxylate reductase [Geobacillus sp. WCH70]
          Length = 327

 Score =  443 bits (1140), Expect = e-122,   Method: Composition-based stats.
 Identities = 118/351 (33%), Positives = 178/351 (50%), Gaps = 26/351 (7%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
           G+  V  T+ +P    I   +     V +       +S + +I+    K D ++  +++ 
Sbjct: 2   GRPYVFITRKLPDD--IIAPIKDIAEVAMWPHDDIPVSRDVLINEAK-KADALLTMVSDV 58

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
             + +  A      K  +NM VG++N+DV AA KYGIAV NTP VLT+TTA+L  +L LA
Sbjct: 59  IDQEVLKAGKSL--KVVANMGVGFDNIDVPAATKYGIAVCNTPDVLTDTTADLTFALLLA 116

Query: 134 AARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
            ARRIVEA +F++ G ++ W P L  G  +  +T+G++G G+IG A A+    GF MN++
Sbjct: 117 TARRIVEAAQFIKEGKWKSWSPFLLAGVDVHHKTIGIVGMGKIGQAVAKRAA-GFDMNIL 175

Query: 194 YFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHL 253
           Y +  ++   EK + A                   S +E+L  AD +     L   T H+
Sbjct: 176 YHNRSRNIEAEKQLGA----------------TYCSFQELLATADFVVCLTPLTNETRHM 219

Query: 254 VNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPF-MKPGLADT 312
            N+E    MK+ AI +N SRG V+DE AL + L    +   GLDVFE EP      L   
Sbjct: 220 FNREAFRKMKQSAIFINASRGAVVDEQALYDALVSGEIAGAGLDVFEHEPIDASHPLLTL 279

Query: 313 KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNEN 363
           KN + +PHI SA+  TR  M  LA+ N++  ++G         V+   N  
Sbjct: 280 KNVVALPHIGSATGETRTKMMELASRNIIAVLQGK---QPETLVNKEWNSR 327
>ref|ZP_00054933.1| COG1052: Lactate dehydrogenase and related dehydrogenases
           [Magnetospirillum magnetotacticum MS-1]
          Length = 328

 Score =  441 bits (1135), Expect = e-122,   Method: Composition-based stats.
 Identities = 102/349 (29%), Positives = 174/349 (49%), Gaps = 29/349 (8%)

Query: 12  PNGKYRVVSTKPMPG---TRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIG 68
           PN K  VV ++ +P    TR + L   +       ++    +S  ++I+ +    D ++ 
Sbjct: 2   PNKKPVVVVSRKLPDVIETRMMELFDTR------LNVDDHPMSKMELIEAVK-IADVLVP 54

Query: 69  QLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAA 128
            +T+     + S       K  +N   G +++D+  A   GI V NTPGVLTE TA++A 
Sbjct: 55  TVTDRIDAGVLSQA-GPNLKLIANFGTGVDHIDLATARSRGIIVTNTPGVLTEDTADMAM 113

Query: 129 SLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGF 188
           +L ++  RRI E +  +R G ++GW P   +G+ + G+ +G+IG GRIG A AR   + F
Sbjct: 114 ALIMSVPRRIAEGERLIRSGDWKGWSPTFMLGHRIWGKRLGIIGMGRIGQAVARR-AKAF 172

Query: 189 KMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDK 248
            M++ Y +  +              +  + E  +      S++++L   D+I++H     
Sbjct: 173 GMSIHYHNRKR--------------VHPDIETELEATYWESLDQMLARMDVITVHCPHTP 218

Query: 249 TTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPG 308
            T+HL++  RL ++ K A +VN +RG ++DE AL   L    +   GLDVFE EP + P 
Sbjct: 219 ATFHLLSARRLELLPKHAYVVNTARGEIVDENALTRMLIRGDLAGAGLDVFEHEPAVNPK 278

Query: 309 LADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVD 357
           L    N +++PH+ SA+   R  M     +N+     G+     P+RV 
Sbjct: 279 LLALDNVVLLPHLGSATIEGRVDMGEKVLVNIKTFADGH---QPPDRVL 324
>ref|YP_762106.1| glyoxylate reductase [Hyphomonas neptunium ATCC 15444]
 gb|ABI76968.1| glyoxylate reductase [Hyphomonas neptunium ATCC 15444]
          Length = 328

 Score =  440 bits (1132), Expect = e-121,   Method: Composition-based stats.
 Identities = 106/349 (30%), Positives = 174/349 (49%), Gaps = 23/349 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P  K +VV T+ +P    + L + +     + +      SVE++   +    D ++  +T
Sbjct: 2   PASKLKVVVTRKLPAP--VELRMKELFDARL-NESDRPFSVEELAQAMQT-ADVLVPTVT 57

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     L +       +  +    G +N+DV +A + GI V NTPGVLT+ TA++A +L 
Sbjct: 58  DKIDGRLMARAGD-QLRLIAQFGAGVDNIDVASAVQRGITVTNTPGVLTDDTADVAMALI 116

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           LA  RR+ E  + M  G ++GW P   +G  L G+ +G+IG GRIG A AR     F M 
Sbjct: 117 LAVPRRMHEGVQIMEAGKFDGWTPTWMMGRRLSGKRLGIIGMGRIGQAVARR-ARAFGMQ 175

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +                 + +  E+ +      S++++L   D++S++      T+
Sbjct: 176 IHYHNRKP--------------VSSRIEESLEATYWDSLDQMLARMDIVSINCPHTPATF 221

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N  RL +MK EA ++N +RG VIDEAAL   ++   +   GLDVFE EP + P L  
Sbjct: 222 HLINARRLGLMKPEAYIINTARGEVIDEAALARAIRAGKIAGAGLDVFEREPAVNPELIG 281

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
             N +++PH+ SA+   R  M     +N+     G+     P+RV P +
Sbjct: 282 LPNVLLLPHMGSATIEGRTEMGEKVIINIKTFADGH---RPPDRVIPAI 327
>ref|ZP_01548851.1| 2-hydroxyacid dehydrogenase [Stappia aggregata IAM 12614]
 gb|EAV42768.1| 2-hydroxyacid dehydrogenase [Stappia aggregata IAM 12614]
          Length = 328

 Score =  437 bits (1125), Expect = e-121,   Method: Composition-based stats.
 Identities = 107/350 (30%), Positives = 179/350 (51%), Gaps = 29/350 (8%)

Query: 14  GKYRVVSTKPMPG---TRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQL 70
            K  VV T+ +P    TR   L   +       +      S  ++++ +    D ++  +
Sbjct: 4   KKPVVVVTRKLPDVVETRMRELFETR------LNDNDRPFSQAELVEAVRT-ADVLVPTV 56

Query: 71  TEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASL 130
           T+    ++ S   +   K  +N   G +N+DV +AN  GI V NTPGVLTE TA++  +L
Sbjct: 57  TDRIDSSVLSQAGE-NLKLIANFGNGVDNIDVVSANNRGINVTNTPGVLTEDTADMTMAL 115

Query: 131 SLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKM 190
            LA  RR+    + +  G + GW P   +G+ + G+ +G+IG GRIG A AR   + F M
Sbjct: 116 ILAVPRRLATGIKALEAGDWAGWSPTWMLGHRIWGKRLGIIGMGRIGQAVARR-AKAFGM 174

Query: 191 NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTT 250
           ++ Y +  +              L  + E+ +      S++++L   D++S+H      T
Sbjct: 175 SIHYHNRRR--------------LAESVEEELEATYWDSLDQMLARMDVVSIHCPHTPGT 220

Query: 251 YHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLA 310
           +HL++  RL ++KK+A +VN +RG VIDE AL+  L+   +   GLDVFE EP + P LA
Sbjct: 221 FHLLSARRLKLLKKDAYVVNTARGEVIDENALIRMLESGELAGAGLDVFEHEPAVNPKLA 280

Query: 311 DTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
             +N +++PH+ SA+   R  M     +N+   + G+     P+RV P +
Sbjct: 281 KLENVLLLPHMGSATIEGRIEMGEKVIINIKTFMDGH---RPPDRVLPSM 327
>sp|Q9C4M5|GYAR_THELI Glyoxylate reductase (Glycolate reductase)
 dbj|BAB40320.1| glyoxylate reductase [Thermococcus litoralis]
          Length = 331

 Score =  437 bits (1124), Expect = e-121,   Method: Composition-based stats.
 Identities = 133/356 (37%), Positives = 198/356 (55%), Gaps = 30/356 (8%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K +V  T+ +P       ++++   +E+    K       +++ +  + D ++  +T+  
Sbjct: 2   KPKVFITRQIPENGIK--MIEKFYEIELWKDPKAPP-RGVLLEKVR-EVDALVTLVTDKV 57

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
            + L     K   K  +  AVGY+N+D+E A K GI V NTPGVLT+ TA+LA +L LA 
Sbjct: 58  DKELLENAPKL--KIIAQYAVGYDNIDIEEATKRGIYVTNTPGVLTDATADLAFALLLAV 115

Query: 135 ARRIVEADEFMRGGLYE----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKM 190
           ARRIVEAD F+R G ++    GW P +F+G  LKG+T+G++G GRIG A A+   +GF M
Sbjct: 116 ARRIVEADAFVRSGEWKKSEVGWHPLMFLGYGLKGKTLGIVGFGRIGQALAKR-AKGFGM 174

Query: 191 NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTT 250
            +IY+   +    E+ + A                     E +L+E+D ISLH  L K T
Sbjct: 175 KIIYYSRTRKPEAEEEIGA----------------EYVDFETLLKESDFISLHVPLTKET 218

Query: 251 YHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLA 310
           YH++ ++ L +MK  AIL+N SRG V+D  AL++ LKE  +   GLDVFEEEP+    L 
Sbjct: 219 YHMIGEKELKLMKPNAILINTSRGAVVDTNALIKALKEGWIAGAGLDVFEEEPYYNEELF 278

Query: 311 DTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASP 366
             KN ++ PHI SA+   REGMA L A N++   KG      PN V+  +  ++ P
Sbjct: 279 KLKNVVLAPHIGSATHEAREGMAELVAKNLIAFAKGEI---PPNLVNKDVLTSSPP 331
>ref|YP_113865.1| 2-hydroxyacid dehydrogenase [Methylococcus capsulatus str. Bath]
 gb|AAU92321.1| D-isomer specific 2-hydroxyacid dehydrogenase family protein
           [Methylococcus capsulatus str. Bath]
          Length = 323

 Score =  435 bits (1120), Expect = e-120,   Method: Composition-based stats.
 Identities = 104/335 (31%), Positives = 170/335 (50%), Gaps = 19/335 (5%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
            K +V+ T+  P +    L         + +     +S +++   + D  D V+  +T+ 
Sbjct: 2   SKPKVLVTRRWPESCESRLRESFHV---VFNADDHPMSRDELKAALRDY-DAVLPTVTDA 57

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
               + S       K   N  VG+N++D++ A + GIAV NTP VLT+ TA++A  L LA
Sbjct: 58  IDADVLSVEP-LRCKILGNFGVGFNHIDLDTARQRGIAVTNTPDVLTDCTADIAMLLMLA 116

Query: 134 AARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
            ARR  E +  +R G + GW P   +G  + G+ +G++G GRI  A A+    GF M +I
Sbjct: 117 VARRGGEGEREVRSGRWTGWRPTHMLGTKVTGKILGLVGFGRIARAMAKKAHFGFDMPVI 176

Query: 194 YFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHL 253
           ++D +                  +    +  ++  ++EEVL  AD ++LH    K   HL
Sbjct: 177 FYDPFPPP--------------QDLIDALGAEQCGTLEEVLERADFVALHCPGSKENRHL 222

Query: 254 VNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTK 313
           +N +RLA MK ++ LVN +RG V+D  AL++ L+   +   GLDV+E EP + PG  +  
Sbjct: 223 INADRLARMKPQSYLVNTARGDVVDNEALIQALRNRRIRGAGLDVYEGEPRLNPGFLELD 282

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYP 348
           N ++ PH+ SA++ TR  M      N+    +G P
Sbjct: 283 NVVLFPHLGSATEETRIAMGMRVIDNITAFFEGRP 317
>ref|YP_001568546.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Petrotoga mobilis SJ95]
 gb|ABX32223.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Petrotoga mobilis SJ95]
          Length = 320

 Score =  435 bits (1119), Expect = e-120,   Method: Composition-based stats.
 Identities = 128/337 (37%), Positives = 192/337 (56%), Gaps = 25/337 (7%)

Query: 17  RVVSTKPMPGTRWINLLVDQGCRVEIC-HLKKTILSVEDIIDLIGDKCDGVIGQLTEDWG 75
           +V  T  +P    I+LL  +    +I  + K  +L+ E++ + I  + D +I  L +   
Sbjct: 3   KVSITYKIP-EAGIDLLKGK---YDIWINPKDKLLTKEELKE-IAKESDALITMLADPID 57

Query: 76  ETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAA 135
             +  A      K  +N AVGYNN+D++ A + GI V NTP VLTETTA+LA +L L  A
Sbjct: 58  SEVLEAGKD-RLKIVANYAVGYNNIDIQKAKELGIYVTNTPDVLTETTADLAWALMLVVA 116

Query: 136 RRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYF 195
           RRIVE+D F R G ++GW P LF+G  + G+T+G+IG G IG A AR    GF M + Y+
Sbjct: 117 RRIVESDAFTREGKFDGWKPELFLGTDVYGKTLGIIGFGSIGQAVARR-AIGFNMKVYYY 175

Query: 196 DLYQ-STRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
             ++ S+  EK + A                   +++E+L+ +D +SLH  L   TYH++
Sbjct: 176 QRHRLSSEKEKALNA----------------TYLNLDELLKVSDYVSLHVPLTDETYHML 219

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKN 314
           ++E+L+++KK A ++N +RGPVIDE AL E LK   +    LDV+E EP + P L D  N
Sbjct: 220 DREKLSLLKKSAFVINTARGPVIDEEALYEKLKSKEISGAALDVYENEPQLTPDLKDLDN 279

Query: 315 AIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWH 351
            ++ PHI SAS  TR  MA + A +++  + G    H
Sbjct: 280 VVLTPHIGSASHETRSRMAQMVAKDIIQALDGETPEH 316
>ref|YP_001534304.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Dinoroseobacter shibae DFL 12]
 gb|ABV94703.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Dinoroseobacter shibae DFL 12]
          Length = 328

 Score =  434 bits (1118), Expect = e-120,   Method: Composition-based stats.
 Identities = 101/349 (28%), Positives = 174/349 (49%), Gaps = 23/349 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P  +  VV T+ +P    +   + +   VE+ +   T +S + +   +  + D ++  ++
Sbjct: 2   PGERLSVVVTRRLPE--AVETRLKELFDVEL-NESDTPMSRDALQAAMR-RADVLVPTVS 57

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     + + +     K  +N   G +++DV  A + GI V NTPGVLT+ TA++  +L 
Sbjct: 58  DHIDGAMLAGVGD-RLKLIANYGAGVDHIDVATARQRGIHVSNTPGVLTDDTADMTLALI 116

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           LA  RRI E    M+ G + GW P   +G  + G+ +G++G GRIG A AR   + F M 
Sbjct: 117 LAVTRRIPEGLALMQTGAWTGWSPTALMGGRIAGRRLGILGMGRIGQAVARR-AKAFGMQ 175

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +  +              L    E+ +      S+++++   D+IS++     +T+
Sbjct: 176 IHYHNRRR--------------LHKGIEEELEATWWESLDQMVSRMDVISVNCPHTPSTF 221

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N  RL +MK  A++VN SRG VIDE AL   L+   +   GLDVFE    + P L +
Sbjct: 222 HLMNARRLKLMKPSAVIVNTSRGEVIDENALTRMLRAGDIAGAGLDVFEHGHEVNPRLRE 281

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
             N +++PH+ SA++  R  M     +N+     G+     P+ V P +
Sbjct: 282 LPNVVLLPHMGSATEEGRAEMGEKVIINIKTFDDGH---RPPDLVVPSM 327
>ref|YP_920227.1| Glyoxylate reductase [Thermofilum pendens Hrk 5]
 gb|ABL78224.1| Glyoxylate reductase [Thermofilum pendens Hrk 5]
          Length = 339

 Score =  434 bits (1117), Expect = e-120,   Method: Composition-based stats.
 Identities = 121/354 (34%), Positives = 190/354 (53%), Gaps = 26/354 (7%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
            + +V  T+ +P       ++ + C V +   K    S E+++  I DK D ++  LT+ 
Sbjct: 2   ARPKVYVTRIIPEPGL--SMLKECCDVVVHESKDWPPSREELLRNIRDK-DALLCLLTDK 58

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
               +  A      K  S  +VG++++D+  A K GI V +TPGVLT+  AE    L LA
Sbjct: 59  IDAEVMDAAPNL--KVISTYSVGFDHIDIPEATKRGIYVTHTPGVLTDAVAEFTVGLILA 116

Query: 134 AARRIVEADEFMRGGLYEG-WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNL 192
             RRIVEAD+ +R G ++  W P+   G  LKG+T+G++G GRIG A A+ +   F + +
Sbjct: 117 VTRRIVEADKIIRTGQWDKPWNPYFLTGPELKGKTIGLVGLGRIGVATAKRL-SSFDVKI 175

Query: 193 IYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYH 252
           +Y+D+ +   +E  +                    + ++ +L ++D++S+H  L K TYH
Sbjct: 176 LYYDIERRWDVETVI---------------PNMEFTDLDTLLEKSDIVSIHVPLTKETYH 220

Query: 253 LVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPF-MKPGLAD 311
           L+N+ERL  MKK A L+N +RGPV+D  ALV+ LKE  +    LDVFE+EP      L  
Sbjct: 221 LINEERLRKMKKTAYLINTARGPVVDTEALVKALKEGWIAGAALDVFEQEPLPPNHPLTK 280

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENAS 365
             N ++ PHIASA+   R+ MA LAA N++  +KG      P  V+  + +   
Sbjct: 281 FDNVVLAPHIASATIEARQRMAELAARNLIAVLKGE---MPPALVNKEVLKVRP 331
>ref|ZP_01168688.1| putative glycerate dehydrogenase [Bacillus sp. NRRL B-14911]
 gb|EAR68647.1| putative glycerate dehydrogenase [Bacillus sp. NRRL B-14911]
          Length = 320

 Score =  434 bits (1117), Expect = e-120,   Method: Composition-based stats.
 Identities = 119/343 (34%), Positives = 187/343 (54%), Gaps = 27/343 (7%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K +V  T+ +P      +  +  C V++   +   +  + I++    + DG++  LTED 
Sbjct: 2   KPKVYITRKIPDDFMAKIKSE--CDVKVWSEEDIPVPRD-ILEAEVAEVDGLLCFLTEDI 58

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
            E++    S+   K  SNMAVGYNN+D+EAA    I V NTPG+LT+TTA+L  +L +AA
Sbjct: 59  DESIIEKASQL--KVISNMAVGYNNIDIEAAKNKRITVTNTPGILTDTTADLTFALLMAA 116

Query: 135 ARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIY 194
           +RRI+E++EF++ G ++ W P    G  + G T+G+IG GRIG A  +   +GF MN IY
Sbjct: 117 SRRIIESNEFLKMGKWKTWSPFQLTGQDVYGATLGIIGMGRIGEALIKR-AKGFSMNCIY 175

Query: 195 FDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
           ++  + T LE+                    +   ++ +L+ AD + +       T +L+
Sbjct: 176 YNRTRKTHLEEE----------------HDIKFEELDHLLQIADFVCILTPYTPETKNLI 219

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMK-PGLADTK 313
           ++  L +MK  +IL+N +RG +++E AL + L    ++  GLDVFE+EP      L    
Sbjct: 220 SERELKLMKSTSILINTARGGIVNEDALYKALTNGEIWAAGLDVFEQEPIDNTHPLMALP 279

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRV 356
           N + +PHI SA+  TR  MA LA  N+L  VKG      PN V
Sbjct: 280 NVVALPHIGSATVKTRMKMAELAVDNLLLGVKGLT----PNSV 318
>ref|ZP_01741677.1| glycerate dehydrogenase [Rhodobacterales bacterium HTCC2150]
 gb|EBA04130.1| glycerate dehydrogenase [Rhodobacterales bacterium HTCC2150]
          Length = 371

 Score =  434 bits (1117), Expect = e-120,   Method: Composition-based stats.
 Identities = 100/351 (28%), Positives = 178/351 (50%), Gaps = 23/351 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P+ +  VV T+ +P    I   + +   V +       ++ ++++  +    D ++  +T
Sbjct: 44  PHKQLSVVVTRRLPEP--IERRLAELFDVNL-RESDAPMTRDELVSAMKT-ADILVPTIT 99

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     + +       K  +N   G ++++V+AA   G+ V NTPGVLTE TA++  +L 
Sbjct: 100 DTIDAEMLAQAGD-QLKLLANYGAGIDHINVDAARARGVLVSNTPGVLTEDTADMTMALI 158

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           LA  RRI +    M+ G +EGW P   +G  + G+ +G++G GRIG A AR     F MN
Sbjct: 159 LAVTRRIPDGLALMQTGQWEGWSPTALMGGRIAGRNLGILGMGRIGQAVARR-ASAFGMN 217

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y + ++              L+   E  +      S+++++   D++S++      T+
Sbjct: 218 VHYHNRHR--------------LRTETEAALNATYWDSLDQMVARTDVLSVNCPHTPATF 263

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N  RL +MK+ A++VN SRG VIDE AL   L+   +   GLDV+E+   + P L +
Sbjct: 264 HLMNARRLKLMKETAVIVNTSRGEVIDENALTRMLRSGEISGAGLDVYEKGREVNPRLRE 323

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNE 362
            KN +++PH+ SA+   R  M     +N+     G+     P+ V P +++
Sbjct: 324 LKNVVLLPHMGSATVEARMEMGEKVLINIKTFDDGH---RPPDLVLPGMDD 371
>ref|ZP_01861538.1| 2-hydroxyacid dehydrogenase [Bacillus sp. SG-1]
 gb|EDL63413.1| 2-hydroxyacid dehydrogenase [Bacillus sp. SG-1]
          Length = 351

 Score =  434 bits (1117), Expect = e-120,   Method: Composition-based stats.
 Identities = 113/344 (32%), Positives = 182/344 (52%), Gaps = 26/344 (7%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K  V  T+ +P     +L   +   VE+   +   +  E +++  G +  G++  L++  
Sbjct: 28  KPYVYVTRKLPEEVLTSL--QEKYEVEMWDDENIAVPREILLEKAG-EASGILSMLSDPI 84

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
              LF        K  +N+AVG++N+D++AAN+  +AV NTP VLT+TTA+L   L +AA
Sbjct: 85  DRELFE--KSPNLKVVANLAVGFDNIDLKAANEKDVAVCNTPDVLTDTTADLTFGLMMAA 142

Query: 135 ARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIY 194
           ARR++EAD+++R G ++ W P L  G  +  +TVG+IG G IG A+AR   +GF MN++Y
Sbjct: 143 ARRLIEADKYVREGKWKSWSPLLMAGTDIHHKTVGIIGMGSIGEAFARR-AKGFDMNILY 201

Query: 195 FDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
            +  +    E+ + A                + +S+EE+L ++D +     L   T  L+
Sbjct: 202 HNRSRKPEAEEVLGA----------------KYASLEELLSQSDYVVCLAPLTPETKGLL 245

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPF-MKPGLADTK 313
            KE+  MMK  AI +N +RGP+++E AL   L +  +   GLDVFE+EP      L    
Sbjct: 246 QKEQFEMMKSSAIFINAARGPIVNEEALYRALVDGEIAAAGLDVFEKEPIDKTHPLLSLD 305

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVD 357
           N + +PHI S+S  TR  M  L   N+   ++G         V+
Sbjct: 306 NVVALPHIGSSSVETRMEMMELCISNIKAVLEG---GTPKTLVN 346
>ref|NP_623521.1| glyoxylate reductase [Thermoanaerobacter tengcongensis MB4]
 gb|AAM25125.1| Lactate dehydrogenase and related dehydrogenases
           [Thermoanaerobacter tengcongensis MB4]
          Length = 324

 Score =  433 bits (1115), Expect = e-119,   Method: Composition-based stats.
 Identities = 133/332 (40%), Positives = 198/332 (59%), Gaps = 23/332 (6%)

Query: 16  YRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWG 75
           ++V  T+ +P    + LL    C VE+      +L+ E++++ I DK D VI QLT+   
Sbjct: 2   FKVFVTRAIPEE-GLELLRK-YCEVEVSPY-DRMLTKEELLEKIKDK-DAVITQLTDKVD 57

Query: 76  ETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAA 135
           +  F A      K  +N AVG++N+D+E A K G+ + NTP VLT  TAELA +L  AAA
Sbjct: 58  KEFFEAAKN--VKIVANYAVGFDNIDLEEATKRGVYITNTPDVLTNATAELAWALLFAAA 115

Query: 136 RRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYF 195
           RR+VEAD+FMR G ++GW P LF+G  + G+T+GVIGAGRIG A+A+ M +GF+M ++Y 
Sbjct: 116 RRVVEADKFMRAGKFQGWAPMLFLGKGVTGKTLGVIGAGRIGQAFAK-MAKGFEMKILYN 174

Query: 196 DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVN 255
                   EK                 T  +   ++ +L+E+D +S+H  L   T HL+ 
Sbjct: 175 ARTPKPEFEKE----------------TGAKYVDLDTLLKESDFVSIHLPLTPETRHLIG 218

Query: 256 KERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNA 315
           +  L +MK  AIL+N  RGPV+DE ALV+ LKE  ++  GLDV+E EP  +  LA+  N 
Sbjct: 219 ERELKLMKNSAILINTGRGPVVDEKALVKALKEKWIYAAGLDVYEREPEFEKELAELDNV 278

Query: 316 IVVPHIASASKWTREGMATLAALNVLGRVKGY 347
           +++PHI SA++  R  M+ L A N++  ++G 
Sbjct: 279 VMLPHIGSATEEARRDMSVLVAQNIIDVIEGR 310
>ref|YP_148818.1| 2-hydroxyacid dehydrogenase [Geobacillus kaustophilus HTA426]
 dbj|BAD77250.1| 2-hydroxyacid dehydrogenase [Geobacillus kaustophilus HTA426]
          Length = 324

 Score =  433 bits (1114), Expect = e-119,   Method: Composition-based stats.
 Identities = 115/343 (33%), Positives = 174/343 (50%), Gaps = 23/343 (6%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K  V  T+ +P      LL      VE+   +   +  + +++    +   ++  +++  
Sbjct: 3   KPYVFITRKLPEDVVAPLL--AIAEVEMWPHEDMAVPHDVLVEKAK-RATAILPMVSDPI 59

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
            E + SA S    +  +NM VGY+N+DV AA   GI V NTP VLT+TTA+L  +L LA 
Sbjct: 60  DEDVLSAGSAL--RVVANMGVGYDNIDVAAAAHRGILVCNTPDVLTDTTADLTFALLLAT 117

Query: 135 ARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIY 194
           ARR+VEA  F++ G ++ W P L  G  +  +T+G++G G IG A A+   +GF MN++Y
Sbjct: 118 ARRLVEAAMFLKEGKWKSWSPFLLAGADVHHKTIGIVGMGNIGQAVAKR-AKGFDMNILY 176

Query: 195 FDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
           ++  +    E+ + A                      ++L E+D +     L   T HL 
Sbjct: 177 YNRSRRPEAEEKLGAV----------------YRPFADLLSESDFVVCLTPLTSETRHLF 220

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEP-FMKPGLADTK 313
           N+E    MKK AI +N +RG V+DE AL E L    +   GLDVFE EP      L    
Sbjct: 221 NREAFRQMKKSAIFINAARGAVVDEQALYEALVGGEIAAAGLDVFEHEPVAADHPLVSLP 280

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRV 356
           N + +PHI SA+  TR  M TLA  N++  ++G P     NR+
Sbjct: 281 NVVALPHIGSATYETRRAMMTLARDNIIAVLEGRPPLTPVNRI 323
>ref|ZP_01444314.1| 2-hydroxyacid dehydrogenase [Roseovarius sp. HTCC2601]
 gb|EAU45472.1| 2-hydroxyacid dehydrogenase [Roseovarius sp. HTCC2601]
          Length = 328

 Score =  432 bits (1112), Expect = e-119,   Method: Composition-based stats.
 Identities = 106/350 (30%), Positives = 176/350 (50%), Gaps = 23/350 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P  +  VV T+ +P    +   + +   V +     T +S  ++ + +  +CD ++  +T
Sbjct: 2   PQKRLSVVVTRRLPE--AVETRLSELFNVTL-RESDTPMSRAELAEAMA-ECDVLVPTIT 57

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     L     +   K  +N   G +++DVE A + GI V NTPGV+T+ TA++   L 
Sbjct: 58  DPIDAGLIGQAGE-RLKLIANYGAGVDHIDVETARRRGILVSNTPGVMTDDTADMVMGLM 116

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           LA  RR+ E    M+ G +EGW P+ F+G  L G+ +G++G GRIG A A+   + F M 
Sbjct: 117 LAVTRRMQEGLAVMQAGTWEGWAPNAFLGTRLGGKRLGILGMGRIGQAVAKR-AQAFGMQ 175

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +  +              L+   E         S+++++   D+IS++     +T+
Sbjct: 176 IHYHNRRR--------------LRPETEDAFEATYWESLDQMVARMDVISVNCPHTPSTF 221

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N  RL +MK  A+LVN SRG VIDE+AL   LK   +   GLDV++      P L +
Sbjct: 222 HLLNARRLKLMKPSAVLVNTSRGEVIDESALTRMLKAGELAGAGLDVYQHGIKGNPELVN 281

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
             N +++PH+ SA+   R  M     LNV     G+     P++V P ++
Sbjct: 282 MPNVVMLPHMGSATIEGRIEMGEKVLLNVKTFADGH---RPPDQVVPAMH 328
>emb|CAO81265.1| glyoxylate reductase (glycolate:NAD+ oxidoreductase) [Candidatus
           Cloacamonas acidaminovorans]
          Length = 317

 Score =  431 bits (1109), Expect = e-119,   Method: Composition-based stats.
 Identities = 132/343 (38%), Positives = 199/343 (58%), Gaps = 27/343 (7%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K  +  T+ +P      L  ++   ++I    +  L+ +++I+ + D  + +I  LT++ 
Sbjct: 2   KPILFLTRRIPEPAIKRL--EEKFTLKINPYNRA-LTHQELIEGVKD-AEALICLLTDNI 57

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
            + + SA  K   K  S+ AVGYNN++VE A + GIAV NTPGVLTETTA+L  +L LA 
Sbjct: 58  DKEVISAAPKL--KVISSYAVGYNNIEVEYATQLGIAVCNTPGVLTETTADLTWALILAT 115

Query: 135 ARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIY 194
            RRI E++ F+R G ++GW P L +G  + G+T+G+IG GRIG A A+    GF M +IY
Sbjct: 116 CRRISESERFLRKGNFKGWEPMLMLGLDVYGKTLGIIGMGRIGQAVAKR-ATGFAMRIIY 174

Query: 195 FDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
           ++    +    F T                   + ++ +L+EAD+I+LH  L K T+HL+
Sbjct: 175 YNDVSVSNTLPFETTE-----------------TDLQTLLKEADIITLHLPLTKETFHLI 217

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKN 314
            KE  A+MK+ A+L+N SRG VIDE  L++ L E  +F  GLDV+E EP +   L   +N
Sbjct: 218 GKEEFALMKENAVLINTSRGAVIDEKELIKALSEKRIFSAGLDVYENEPDIPQELLALEN 277

Query: 315 AIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVD 357
            +++PHI SAS  TR  MA LAA N +  +KG      P +V+
Sbjct: 278 VVLLPHIGSASIETRTKMALLAAENAIAVMKGR---KPPAQVN 317
Searching..................................................done Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

gb|ABK96544.1|  unknown [Populus trichocarpa x Populus delto...   499   e-139
gb|AAO73867.1|AF503361_1  putative NADH-dependent hydroxypyr...   497   e-139
dbj|BAG09374.1|  peroxisomal hydroxypyruvate reductase [Glyc...   495   e-138
dbj|BAB44155.1|  hydroxypyruvate reductase [Bruguiera gymnor...   495   e-138
gb|AAO73866.1|AF503360_1  putative NADH-dependent hydroxypyr...   495   e-138
emb|CAO47393.1|  unnamed protein product [Vitis vinifera]         494   e-138
ref|NP_176968.1|  HPR (HYDROXYPYRUVATE REDUCTASE); glycerate...   494   e-138
gb|ABL10359.1|  hydroxypyruvate reductase [Solenostemon scut...   494   e-138
dbj|BAA19751.1|  hydroxypyruvate reductase [Arabidopsis thal...   493   e-138
dbj|BAA08410.1|  hydroxypyruvate reductase [Cucurbita cv. Ku...   492   e-137
emb|CAN65023.1|  hypothetical protein [Vitis vinifera]            490   e-137
gb|ABK21250.1|  unknown [Picea sitchensis]                        489   e-136
sp|P13443|DHGY_CUCSA  Glycerate dehydrogenase (NADH-dependen...   487   e-136
ref|NP_001045589.1|  Os02g0101500 [Oryza sativa (japonica cu...   486   e-135
dbj|BAA08411.1|  hydroxypyruvate reductase [Cucurbita cv. Ku...   485   e-135
ref|YP_001471315.1|  D-isomer specific 2-hydroxyacid dehydro...   479   e-133
ref|ZP_01368724.1|  D-isomer specific 2-hydroxyacid dehydrog...   478   e-133
ref|NP_422516.1|  2-hydroxyacid dehydrogenase [Caulobacter c...   474   e-132
ref|YP_419558.1|  Lactate dehydrogenase and related dehydrog...   473   e-131
ref|ZP_01666395.1|  D-isomer specific 2-hydroxyacid dehydrog...   472   e-131
ref|YP_517906.1|  hypothetical protein DSY1673 [Desulfitobac...   472   e-131
ref|NP_578048.1|  glyoxylate reductase [Pyrococcus furiosus ...   472   e-131
ref|YP_001686676.1|  Glyoxylate reductase [Caulobacter sp. K...   471   e-131
ref|ZP_00054933.1|  COG1052: Lactate dehydrogenase and relat...   470   e-130
ref|ZP_01548851.1|  2-hydroxyacid dehydrogenase [Stappia agg...   469   e-130
ref|YP_001410651.1|  Glyoxylate reductase [Fervidobacterium ...   469   e-130
ref|YP_762106.1|  glyoxylate reductase [Hyphomonas neptunium...   465   e-129
ref|YP_001737977.1|  Glyoxylate reductase [Candidatus Korarc...   465   e-129
ref|YP_113865.1|  2-hydroxyacid dehydrogenase [Methylococcus...   465   e-129
ref|YP_183096.1|  glyoxylate reductase [Thermococcus kodakar...   465   e-129
ref|ZP_02913953.1|  Glyoxylate reductase [Geobacillus sp. WC...   465   e-129
ref|YP_001534304.1|  D-isomer specific 2-hydroxyacid dehydro...   463   e-128
ref|ZP_01861538.1|  2-hydroxyacid dehydrogenase [Bacillus sp...   462   e-128
sp|Q9C4M5|GYAR_THELI  Glyoxylate reductase (Glycolate reduct...   462   e-128
ref|ZP_01741677.1|  glycerate dehydrogenase [Rhodobacterales...   459   e-127
ref|YP_077041.1|  putative glycerate dehydrogenase [Symbioba...   459   e-127
ref|ZP_01444314.1|  2-hydroxyacid dehydrogenase [Roseovarius...   459   e-127
ref|ZP_03856830.1|  lactate dehydrogenase-like oxidoreductas...   457   e-127
ref|YP_612475.1|  Glycolate reductase [Silicibacter sp. TM10...   457   e-127
ref|ZP_02164852.1|  2-hydroxyacid dehydrogenase [Hoeflea pho...   457   e-127
ref|YP_765750.1|  putative glyoxylate reductase [Rhizobium l...   457   e-127
ref|YP_001414898.1|  Glyoxylate reductase [Parvibaculum lava...   456   e-126
ref|ZP_02294079.1|  Glyoxylate reductase [Rhizobium legumino...   456   e-126
ref|ZP_02144459.1|  hypothetical protein RGBS107_02823 [Phae...   456   e-126
ref|ZP_02190699.1|  Lactate dehydrogenase and related dehydr...   456   e-126
ref|ZP_02855508.1|  Glyoxylate reductase [Rhizobium legumino...   455   e-126
ref|YP_508857.1|  Glycolate reductase [Jannaschia sp. CCS1] ...   455   e-126
ref|YP_467690.1|  probable D-2-hydroxyacid dehydrogenase pro...   455   e-126
ref|YP_676475.1|  D-isomer specific 2-hydroxyacid dehydrogen...   454   e-126
ref|NP_384280.1|  2-hydroxyacid dehydrogenase [Sinorhizobium...   454   e-126
ref|YP_001329036.1|  Glyoxylate reductase [Sinorhizobium med...   454   e-126
ref|YP_920227.1|  Glyoxylate reductase [Thermofilum pendens ...   454   e-126
emb|CAM75169.1|  Glyoxylate reductase [Magnetospirillum gryp...   454   e-126
ref|NP_540869.1|  2-hydroxyacid dehydrogenase [Brucella meli...   453   e-125
ref|YP_001127005.1|  Glycerate dehydrogenase [Geobacillus th...   452   e-125
ref|YP_148818.1|  2-hydroxyacid dehydrogenase [Geobacillus k...   452   e-125
ref|YP_430795.1|  D-isomer specific 2-hydroxyacid dehydrogen...   451   e-125
ref|XP_001784621.1|  predicted protein [Physcomitrella paten...   450   e-125
ref|NP_699151.1|  2-hydroxyacid dehydrogenase [Brucella suis...   450   e-125
ref|NP_148197.2|  glyoxylate reductase [Aeropyrum pernix K1]...   450   e-125
ref|YP_001565752.1|  D-isomer specific 2-hydroxyacid dehydro...   450   e-124
ref|ZP_01750631.1|  Glycolate reductase [Roseobacter sp. CCS...   449   e-124
ref|YP_222806.1|  2-hydroxyacid dehydrogenase [Brucella abor...   448   e-124
ref|ZP_02121344.1|  Glyoxylate reductase [Methylobacterium n...   448   e-124
ref|YP_986727.1|  D-isomer specific 2-hydroxyacid dehydrogen...   447   e-124
emb|CAM32608.1|  Dehydrogenase oxidoreductase protein [Herba...   447   e-124
ref|YP_001155374.1|  D-isomer specific 2-hydroxyacid dehydro...   447   e-124
ref|YP_001099124.1|  putative glyoxylate reductase (Glycolat...   447   e-124
ref|YP_615831.1|  Glycolate reductase [Sphingopyxis alaskens...   447   e-124
ref|ZP_01521900.1|  D-isomer specific 2-hydroxyacid dehydrog...   447   e-124
ref|YP_002827974.1|  2-hydroxyacid dehydrogenase [Rhizobium ...   447   e-124
ref|ZP_01168688.1|  putative glycerate dehydrogenase [Bacill...   447   e-124
ref|YP_001369285.1|  Glyoxylate reductase [Ochrobactrum anth...   447   e-123
ref|ZP_01003291.1|  2-hydroxyacid dehydrogenase [Loktanella ...   446   e-123
ref|ZP_01054845.1|  2-hydroxyacid dehydrogenase [Roseobacter...   445   e-123
ref|YP_971639.1|  D-isomer specific 2-hydroxyacid dehydrogen...   445   e-123
ref|YP_684368.1|  glyoxylate reductase [Roseobacter denitrif...   445   e-123
ref|NP_353111.1|  D-isomer specific 2-hydroxyacid dehydrogen...   445   e-123
ref|YP_848018.1|  D-isomer specific 2-hydroxyacid dehydrogen...   445   e-123
ref|ZP_01037723.1|  2-hydroxyacid dehydrogenase [Roseovarius...   444   e-123
ref|YP_001419005.1|  Glyoxylate reductase [Xanthobacter auto...   444   e-123
ref|YP_001831652.1|  Glyoxylate reductase [Beijerinckia indi...   444   e-123
ref|ZP_02147929.1|  2-hydroxyacid dehydrogenase [Phaeobacter...   444   e-123
ref|YP_001923204.1|  D-isomer specific 2-hydroxyacid dehydro...   444   e-123
ref|NP_522506.1|  2-hydroxyacid dehydrogenase [Ralstonia sol...   444   e-123
gb|EDT28874.1|  glyoxylate reductase [Oligotropha carboxidov...   444   e-123
ref|XP_001752353.1|  predicted protein [Physcomitrella paten...   443   e-122
ref|ZP_00944908.1|  2-hydroxyacid dehydrogenase [Ralstonia s...   442   e-122
ref|YP_001769127.1|  Glyoxylate reductase [Methylobacterium ...   442   e-122
ref|YP_001236280.1|  putative Glyoxylate reductase [Bradyrhi...   442   e-122
emb|CAO81265.1|  glyoxylate reductase (glycolate:NAD+ oxidor...   442   e-122
ref|YP_001755355.1|  D-isomer specific 2-hydroxyacid dehydro...   442   e-122
ref|YP_428871.1|  Glycolate reductase [Rhodospirillum rubrum...   442   e-122
ref|ZP_02941201.1|  Glyoxylate reductase [Cyanothece sp. PCC...   442   e-122
ref|NP_623521.1|  glyoxylate reductase [Thermoanaerobacter t...   442   e-122
ref|ZP_00960504.1|  2-hydroxyacid dehydrogenase [Roseovarius...   442   e-122
ref|ZP_02056254.1|  Glyoxylate reductase [Methylobacterium c...   441   e-122
ref|ZP_01447132.1|  2-hydroxyacid dehydrogenase [alpha prote...   441   e-122
ref|YP_001568546.1|  D-isomer specific 2-hydroxyacid dehydro...   441   e-122
ref|YP_001935995.1|  2-hydroxyacid dehydrogenase [Brucella a...   440   e-122
ref|ZP_00956178.1|  2-hydroxyacid dehydrogenase [Sulfitobact...   440   e-122
ref|YP_779183.1|  Glyoxylate reductase [Rhodopseudomonas pal...   440   e-122
ref|YP_001179183.1|  D-isomer specific 2-hydroxyacid dehydro...   440   e-122
ref|YP_484238.1|  Glycolate reductase [Rhodopseudomonas palu...   440   e-122
ref|YP_001202288.1|  putative D-isomer specific 2-hydroxyaci...   440   e-122
ref|YP_001434366.1|  Glyoxylate reductase [Roseiflexus caste...   440   e-122
ref|YP_316657.1|  2-hydroxyacid dehydrogenase [Nitrobacter w...   439   e-121
ref|YP_001352411.1|  2-hydroxyacid dehydrogenase [Janthinoba...   439   e-121
ref|ZP_01173412.1|  hypothetical protein B14911_09477 [Bacil...   439   e-121
ref|ZP_02947547.1|  Glyoxylate reductase [Methylocella silve...   438   e-121
ref|YP_001274602.1|  Glyoxylate reductase [Roseiflexus sp. R...   438   e-121
ref|YP_530248.1|  D-isomer specific 2-hydroxyacid dehydrogen...   438   e-121
ref|YP_001488104.1|  D-isomer specific 2-hydroxyacid dehydro...   437   e-121
ref|ZP_01014196.1|  2-hydroxyacid dehydrogenase [Rhodobacter...   437   e-121
ref|YP_080512.1|  D-isomer specific 2-hydroxyacid dehydrogen...   437   e-121
ref|YP_001328057.1|  D-isomer specific 2-hydroxyacid dehydro...   437   e-121
ref|NP_436410.1|  2-hydroxyacid dehydrogenase [Sinorhizobium...   437   e-121
ref|YP_001020708.1|  putative 2-hydroxyacid dehydrogenase [M...   436   e-120
ref|YP_001523152.1|  putative dehydrogenase [Azorhizobium ca...   436   e-120
ref|ZP_02838365.1|  Glyoxylate reductase [Arthrobacter chlor...   436   e-120
ref|ZP_01035877.1|  D-isomer specific 2-hydroxyacid dehydrog...   436   e-120
ref|ZP_01666712.1|  D-isomer specific 2-hydroxyacid dehydrog...   435   e-120
ref|YP_520253.1|  hypothetical protein DSY4020 [Desulfitobac...   435   e-120
ref|ZP_02151949.1|  2-hydroxyacid dehydrogenase [Oceanibulbu...   435   e-120
ref|YP_165887.1|  2-hydroxyacid dehydrogenase [Silicibacter ...   435   e-120
ref|ZP_01753096.1|  2-hydroxyacid dehydrogenase [Roseobacter...   435   e-120
ref|ZP_02129818.1|  Glyoxylate reductase [Desulfatibacillum ...   435   e-120
ref|NP_001084647.1|  hypothetical protein LOC414606 [Xenopus...   435   e-120
ref|YP_947693.1|  D-isomer specific 2-hydroxyacid dehydrogen...   434   e-120
ref|YP_001791021.1|  D-isomer specific 2-hydroxyacid dehydro...   434   e-120
ref|XP_580934.3|  PREDICTED: similar to Chain A, Ternary Cry...   434   e-120
ref|YP_001662713.1|  D-isomer specific 2-hydroxyacid dehydro...   434   e-120
ref|ZP_02171588.1|  protein of unknown function DUF881 [Baci...   434   e-120
ref|YP_681501.1|  glyoxylate reductase [Roseobacter denitrif...   434   e-120
ref|YP_001896547.1|  D-isomer specific 2-hydroxyacid dehydro...   434   e-120
ref|ZP_01012068.1|  D-isomer specific 2-hydroxyacid dehydrog...   434   e-120
ref|ZP_01902582.1|  2-hydroxyacid dehydrogenase [Roseobacter...   433   e-120
ref|ZP_01045151.1|  2-hydroxyacid dehydrogenase [Nitrobacter...   433   e-119
ref|ZP_01878191.1|  D-isomer specific 2-hydroxyacid dehydrog...   433   e-119
ref|YP_352368.1|  2-hydroxyacid dehydrogenase [Rhodobacter s...   433   e-119
ref|YP_166811.1|  2-hydroxyacid dehydrogenase [Silicibacter ...   432   e-119
ref|ZP_02142939.1|  glyoxylate reductase [Roseobacter litora...   432   e-119
ref|YP_001042870.1|  Glyoxylate reductase [Rhodobacter sphae...   432   e-119
ref|YP_001664595.1|  D-isomer specific 2-hydroxyacid dehydro...   432   e-119
ref|ZP_01904616.1|  pyrroline-5-carboxylate reductase [Roseo...   432   e-119
ref|NP_945775.1|  2-hydroxyacid dehydrogenase [Rhodopseudomo...   432   e-119
ref|YP_559944.1|  Putative 2-ketogluconate reductase [Burkho...   431   e-119
ref|NP_391348.1|  gluconate 2-dehydrogenase [Bacillus subtil...   431   e-119
ref|ZP_02887490.1|  D-isomer specific 2-hydroxyacid dehydrog...   431   e-119
ref|YP_567358.1|  D-isomer specific 2-hydroxyacid dehydrogen...   431   e-119
ref|XP_854862.1|  PREDICTED: similar to Glyoxylate reductase...   431   e-119
ref|YP_001155168.1|  D-isomer specific 2-hydroxyacid dehydro...   430   e-119
ref|ZP_02989735.1|  D-isomer specific 2-hydroxyacid dehydrog...   430   e-118
gb|AAS64128.1|  putative D-isomer specific 2-hydroxyaciddehy...   430   e-118
gb|EAZ21390.1|  hypothetical protein OsJ_004873 [Oryza sativ...   430   e-118
gb|AAB18530.1|  unnamed protein product [Escherichia coli]        429   e-118
ref|YP_001696599.1|  Glyoxylate reductase [Lysinibacillus sp...   429   e-118
ref|ZP_01228415.1|  D-isomer specific 2-hydroxyacid dehydrog...   429   e-118
ref|ZP_01439199.1|  2-hydroxyacid dehydrogenase [Fulvimarina...   429   e-118
ref|YP_727037.1|  lactate dehydrogenase or related dehydroge...   429   e-118
ref|YP_683614.1|  glyoxylate reductase [Roseobacter denitrif...   428   e-118
ref|YP_575406.1|  Glycolate reductase [Nitrobacter hamburgen...   428   e-118
ref|NP_693278.1|  glycerate dehydrogenase [Oceanobacillus ih...   427   e-118
gb|AAM87639.1|AE014011_6  putative dehydrogenase [Yersinia p...   427   e-118
ref|YP_001190357.1|  Glyoxylate reductase [Metallosphaera se...   427   e-118
ref|NP_001018361.1|  glyoxylate reductase/hydroxypyruvate re...   427   e-118
pdb|2GCG|A  Chain A, Ternary Crystal Structure Of Human Glyo...   427   e-118
ref|NP_036335.1|  glyoxylate reductase/hydroxypyruvate reduc...   427   e-117
ref|YP_001337568.1|  2-hydroxyacid dehydrogenase [Klebsiella...   426   e-117
ref|NP_244180.1|  glycerate dehydrogenase [Bacillus halodura...   426   e-117
ref|NP_407503.1|  2-hydroxyacid dehydrogenase [Yersinia pest...   426   e-117
ref|YP_001422754.1|  YvcT [Bacillus amyloliquefaciens FZB42]...   426   e-117
ref|YP_001476295.1|  D-isomer specific 2-hydroxyacid dehydro...   426   e-117
ref|YP_001306138.1|  D-isomer specific 2-hydroxyacid dehydro...   426   e-117
ref|ZP_02737749.1|  probable 2-hydroxyacid dehydrogenase [Ge...   426   e-117
ref|YP_001168382.1|  Glyoxylate reductase [Rhodobacter sphae...   425   e-117
ref|XP_001504338.1|  PREDICTED: similar to Chain A, Ternary ...   425   e-117
gb|EAY84074.1|  hypothetical protein OsI_005307 [Oryza sativ...   425   e-117
emb|CAE30406.1|  novel protein similar to human glyoxylate r...   425   e-117
ref|YP_364607.1|  2-hydroxyacid dehydrogenase [Xanthomonas c...   425   e-117
emb|CAH89789.1|  hypothetical protein [Pongo abelii]              425   e-117
ref|YP_001857046.1|  D-isomer specific 2-hydroxyacid dehydro...   425   e-117
gb|ABB68037.1|  putative dehydrogenase [Shigella boydii Sb227]    425   e-117
ref|YP_649650.1|  D-isomer specific 2-hydroxyacid dehydrogen...   424   e-117
ref|YP_409865.2|  putative dehydrogenase [Shigella boydii Sb...   424   e-117
ref|ZP_02139806.1|  glyoxylate reductase [Roseobacter litora...   424   e-117
ref|XP_424417.2|  PREDICTED: similar to MGC82214 protein [Ga...   424   e-117
ref|ZP_00833513.1|  COG1052: Lactate dehydrogenase and relat...   424   e-117
ref|YP_253938.1|  hypothetical protein SH2023 [Staphylococcu...   424   e-117
ref|ZP_00824069.1|  COG1052: Lactate dehydrogenase and relat...   424   e-117
ref|YP_296488.1|  2-hydroxyacid dehydrogenase [Ralstonia eut...   424   e-117
ref|ZP_02007136.1|  Gluconate 2-dehydrogenase [Ralstonia pic...   423   e-117
ref|YP_543052.1|  putative dehydrogenase [Escherichia coli U...   423   e-116
ref|NP_106212.1|  2-hydroxyacid dehydrogenase [Mesorhizobium...   423   e-116
ref|YP_001718784.1|  D-isomer specific 2-hydroxyacid dehydro...   423   e-116
ref|ZP_00711407.1|  COG1052: Lactate dehydrogenase and relat...   422   e-116
gb|ABB64241.1|  putative dehydrogenase [Shigella dysenteriae...   422   e-116
ref|ZP_01755871.1|  glycerate dehydrogenase [Roseobacter sp....   422   e-116
ref|YP_001460346.1|  2-ketogluconate reductase [Escherichia ...   422   e-116
ref|NP_001107226.1|  glyoxylate reductase/hydroxypyruvate re...   422   e-116
ref|YP_001723172.1|  D-isomer specific 2-hydroxyacid dehydro...   422   e-116
gb|AAN82808.1|AE016768_226  2-ketogluconate reductase [Esche...   422   e-116
ref|ZP_01747987.1|  2-hydroxyacid dehydrogenase [Sagittula s...   422   e-116
ref|ZP_00726400.1|  COG1052: Lactate dehydrogenase and relat...   422   e-116
ref|NP_525028.1|  glyoxylate reductase/hydroxypyruvate reduc...   422   e-116
ref|ZP_02293529.1|  D-isomer specific 2-hydroxyacid dehydrog...   422   e-116
ref|YP_405732.2|  putative dehydrogenase [Shigella dysenteri...   422   e-116
ref|YP_080803.1|  probable 2-ketogluconate reductase YvcT [B...   422   e-116
gb|AAZ90377.1|  putative dehydrogenase [Shigella sonnei Ss046]    422   e-116
ref|ZP_01439868.1|  2-hydroxyacid dehydrogenase [Fulvimarina...   422   e-116
ref|ZP_01187992.1|  D-isomer specific 2-hydroxyacid dehydrog...   422   e-116
ref|YP_497579.1|  Glycolate reductase [Novosphingobium aroma...   421   e-116
ref|YP_002807903.1|  conserved hypothetical protein [Escheri...   421   e-116
ref|YP_458233.1|  D-isomer specific 2-hydroxyacid dehydrogen...   421   e-116
ref|NP_756234.2|  2-hydroxyacid dehydrogenase [Escherichia c...   421   e-116
ref|ZP_00829300.1|  COG1052: Lactate dehydrogenase and relat...   421   e-116
ref|YP_549890.1|  D-isomer specific 2-hydroxyacid dehydrogen...   421   e-116
ref|YP_312612.2|  putative dehydrogenase [Shigella sonnei Ss...   421   e-116
ref|ZP_00923022.1|  COG1052: Lactate dehydrogenase and relat...   421   e-116
ref|AP_004241.1|  2-keto-D-gluconate reductase [Escherichia ...   421   e-116
ref|NP_767406.1|  2-hydroxyacid dehydrogenase [Bradyrhizobiu...   421   e-116
ref|YP_996837.1|  D-isomer specific 2-hydroxyacid dehydrogen...   420   e-116
ref|YP_981857.1|  D-isomer specific 2-hydroxyacid dehydrogen...   420   e-116
ref|YP_001745839.1|  2-ketogluconate reductase [Escherichia ...   420   e-116
dbj|BAA29686.1|  376aa long hypothetical dehydrogenase [Pyro...   420   e-116
ref|ZP_00629674.1|  Glycolate reductase [Paracoccus denitrif...   420   e-116
ref|NP_839339.1|  2-hydroxyacid dehydrogenase [Shigella flex...   420   e-116
ref|YP_259824.1|  2-ketogluconate 6-phosphate reductase, put...   420   e-115
ref|ZP_00998168.1|  D-isomer specific 2-hydroxyacid dehydrog...   420   e-115
ref|YP_523399.1|  D-isomer specific 2-hydroxyacid dehydrogen...   420   e-115
ref|ZP_02153103.1|  D-isomer specific 2-hydroxyacid dehydrog...   420   e-115
ref|YP_001488322.1|  gluconate 2-dehydrogenase [Bacillus pum...   419   e-115
ref|XP_001371693.1|  PREDICTED: similar to Chain A, Ternary ...   419   e-115
ref|ZP_00717959.1|  COG1052: Lactate dehydrogenase and relat...   419   e-115
ref|YP_690875.1|  putative dehydrogenase [Shigella flexneri ...   419   e-115
ref|ZP_01039826.1|  2-hydroxyacid dehydrogenase [Erythrobact...   419   e-115
ref|ZP_02901457.1|  2-ketogluconate reductase [Escherichia a...   418   e-115
ref|ZP_02387834.1|  glyoxylate reductase [Burkholderia thail...   418   e-115
gb|EEJ90696.1|  lactate dehydrogenase-like oxidoreductase [M...   418   e-115
ref|ZP_00823666.1|  COG1052: Lactate dehydrogenase and relat...   418   e-115
ref|YP_001440192.1|  hypothetical protein ESA_04175 [Enterob...   417   e-115
ref|YP_001456488.1|  hypothetical protein CKO_05009 [Citroba...   417   e-115
ref|ZP_02356479.1|  glyoxylate reductase [Burkholderia oklah...   417   e-115
ref|ZP_01448595.1|  2-hydroxyacid dehydrogenase [alpha prote...   417   e-115
ref|YP_442235.2|  glyoxylate reductase [Burkholderia thailan...   417   e-115
ref|NP_386583.1|  2-hydroxyacid dehydrogenase [Sinorhizobium...   417   e-115
ref|YP_001008293.1|  putative D-isomer specific 2-hydroxyaci...   417   e-115
ref|YP_643402.1|  D-isomer specific 2-hydroxyacid dehydrogen...   417   e-114
ref|ZP_02373994.1|  glyoxylate reductase [Burkholderia thail...   417   e-114
gb|EEH95408.1|  glyoxylate/hydroxypyruvate reductase B [Citr...   417   e-114
gb|ABC36478.1|  glyoxylate reductase [Burkholderia thailande...   416   e-114
ref|NP_867230.1|  probable 2-hydroxyacid dehydrogenase [Rhod...   416   e-114
ref|ZP_01696182.1|  D-isomer specific 2-hydroxyacid dehydrog...   416   e-114
ref|ZP_01370695.1|  D-isomer specific 2-hydroxyacid dehydrog...   416   e-114
ref|ZP_03938310.1|  possible glyoxylate reductase [Lactobaci...   416   e-114
ref|ZP_02464263.1|  2-hydroxyacid dehydrogenase [Burkholderi...   416   e-114
ref|YP_040314.1|  D-isomer specific 2-hydroxyacid dehydrogen...   416   e-114
ref|YP_201899.1|  2-hydroxyacid dehydrogenase [Xanthomonas o...   416   e-114
ref|ZP_01755592.1|  D-isomer specific 2-hydroxyacid dehydrog...   416   e-114
ref|YP_519675.1|  hypothetical protein DSY3442 [Desulfitobac...   415   e-114
ref|ZP_03941324.1|  possible glyoxylate reductase [Lactobaci...   415   e-114
ref|ZP_03953531.1|  possible glyoxylate reductase [Lactobaci...   415   e-114
ref|ZP_01862964.1|  D-isomer specific 2-hydroxyacid dehydrog...   415   e-114
ref|YP_109051.1|  2-hydroxyacid dehydrogenase [Burkholderia ...   415   e-114
gb|ABD97861.1|  NADH-dependent hydroxypyruvate reductase [Pa...   415   e-114
ref|ZP_01320783.1|  hypothetical protein BpseP_03005472 [Bur...   415   e-114
ref|NP_142561.2|  glyoxylate reductase [Pyrococcus horikoshi...   415   e-114
ref|YP_001764361.1|  D-isomer specific 2-hydroxyacid dehydro...   415   e-114
ref|XP_973278.1|  PREDICTED: similar to CG1236-PA [Tribolium...   415   e-114
ref|YP_001174908.1|  D-isomer specific 2-hydroxyacid dehydro...   414   e-114
ref|YP_620507.1|  D-isomer specific 2-hydroxyacid dehydrogen...   414   e-114
ref|YP_416286.1|  glycerate dehydrogenase [Staphylococcus au...   414   e-114
ref|NP_371454.1|  similar to glycerate dehydrogenase [Staphy...   413   e-114
ref|NP_643033.1|  2-hydroxyacid dehydrogenase [Xanthomonas a...   413   e-113
ref|ZP_00961432.1|  D-isomer specific 2-hydroxyacid dehydrog...   413   e-113
ref|ZP_02243841.1|  2-hydroxyacid dehydrogenase [Xanthomonas...   413   e-113
ref|ZP_03834588.1|  hypothetical protein CATC2_01255 [Citrob...   413   e-113
gb|AAU49757.1|  glyoxylate reductase [Burkholderia mallei AT...   413   e-113
ref|ZP_00986479.1|  COG1052: Lactate dehydrogenase and relat...   413   e-113
ref|ZP_00418975.1|  D-isomer specific 2-hydroxyacid dehydrog...   413   e-113
ref|ZP_02456664.1|  D-isomer specific 2-hydroxyacid dehydrog...   413   e-113
ref|YP_993802.1|  glyoxylate reductase [Burkholderia mallei ...   412   e-113
ref|ZP_02114627.1|  D-isomer specific 2-hydroxyacid dehydrog...   412   e-113
ref|ZP_01741000.1|  D-isomer specific 2-hydroxyacid dehydrog...   412   e-113
ref|ZP_02499004.1|  D-isomer specific 2-hydroxyacid dehydrog...   412   e-113
ref|YP_346668.1|  2-hydroxyacid dehydrogenase [Pseudomonas f...   412   e-113
ref|NP_645629.1|  hypothetical protein MW0812 [Staphylococcu...   411   e-113
ref|YP_001909347.1|  2-ketogluconate reductase [Erwinia tasm...   411   e-113
ref|XP_001691480.1|  hydroxypyruvate reductase [Chlamydomona...   411   e-113
ref|YP_001067117.1|  D-isomer specific 2-hydroxyacid dehydro...   411   e-113
ref|YP_001028734.1|  glyoxylate reductase [Burkholderia mall...   411   e-113
ref|ZP_00982051.1|  COG1052: Lactate dehydrogenase and relat...   410   e-113
ref|YP_368457.1|  2-hydroxyacid dehydrogenase [Burkholderia ...   410   e-113
pdb|2H1S|A  Chain A, Crystal Structure Of A GlyoxylateHYDROX...   410   e-113
ref|ZP_02355535.1|  gluconate 2-dehydrogenase [Burkholderia ...   410   e-113
ref|YP_001679796.1|  glyoxylate reductase [Heliobacterium mo...   410   e-113
emb|CAG06267.1|  unnamed protein product [Tetraodon nigrovir...   410   e-113
ref|YP_452117.1|  2-hydroxyacid dehydrogenase [Xanthomonas o...   410   e-112
ref|ZP_02482681.1|  D-isomer specific 2-hydroxyacid dehydrog...   409   e-112
ref|YP_301935.1|  putative dehydrogenase [Staphylococcus sap...   409   e-112
Sequences not found previously or not previously below threshold:

>gb|ABK96544.1| unknown [Populus trichocarpa x Populus deltoides]
          Length = 386

 Score =  499 bits (1287), Expect = e-139,   Method: Composition-based stats.
 Identities = 345/386 (89%), Positives = 371/386 (96%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEVYNPNGKYRVVSTK MPGTRWINLL++Q CRVEIC  KKTILSVEDII LIG
Sbjct: 1   MAKPISIEVYNPNGKYRVVSTKSMPGTRWINLLIEQDCRVEICTQKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLF+ALS+AGGKAFSNMAVGYNNVDV AANK+G+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFAALSRAGGKAFSNMAVGYNNVDVNAANKHGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEAD+FMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAYG+FLKANGEQPVTWKRA+SM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYGEFLKANGEQPVTWKRAASMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHP+LDKTTYHL+NKE LA MKKEAILVNCSRGPV+DE ALVEHLK+NPMFRVGLDVFE
Sbjct: 241 SLHPILDKTTYHLINKESLATMKKEAILVNCSRGPVVDEVALVEHLKQNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNA+VVPHIASASKWTREGMATLAALNVLG++KGYP+W DPN+V PFL
Sbjct: 301 DEPYMKPGLADMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGDPNQVAPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP ASPSIVN+KALGLPVSKL
Sbjct: 361 NENAPPPAASPSIVNAKALGLPVSKL 386
>gb|AAO73867.1|AF503361_1 putative NADH-dependent hydroxypyruvate reductase [Glycine max]
          Length = 386

 Score =  497 bits (1280), Expect = e-139,   Method: Composition-based stats.
 Identities = 344/386 (89%), Positives = 365/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP+GKYRVVSTKPMPGTRWINLL+    R+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPSGKYRVVSTKPMPGTRWINLLIQNDVRLEICTEKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALSKAGGKAFSNMAVGYNNVDV+AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEELFSALSKAGGKAFSNMAVGYNNVDVDAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASL+LAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLTLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAY  FLKANGE PVTWKRA++M+EVL+EAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYAAFLKANGETPVTWKRAATMDEVLQEADII 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAIL+NCSRGPVIDEAALVEHLK NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILINCSRGPVIDEAALVEHLKHNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG+VKGYP+W D NRV+PFL
Sbjct: 301 EEPYMKPGLAELKNAIVVPHIASASKWTREGMATLAALNVLGKVKGYPVWFDANRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP A PSIVN+KALGLP SKL
Sbjct: 361 NENARPPAACPSIVNAKALGLPTSKL 386
>dbj|BAG09374.1| peroxisomal hydroxypyruvate reductase [Glycine max]
          Length = 386

 Score =  495 bits (1276), Expect = e-138,   Method: Composition-based stats.
 Identities = 343/386 (88%), Positives = 365/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP+GKYRVVSTKPMPGTRWINLL+    R+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPSGKYRVVSTKPMPGTRWINLLIQNDVRLEICTEKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALSKAGGKAFSNMAVGYNNVDV+AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEELFSALSKAGGKAFSNMAVGYNNVDVDAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASL+LAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLTLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAY  FLKANGE PVTWKRA++M+EVL+EAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYAAFLKANGETPVTWKRAATMDEVLQEADII 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAIL+NCSRGPVIDEAALVEHLK NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILINCSRGPVIDEAALVEHLKHNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG+VKGYP+W D N+V+PFL
Sbjct: 301 EEPYMKPGLAELKNAIVVPHIASASKWTREGMATLAALNVLGKVKGYPVWFDANKVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP A PSIVN+KALGLP SKL
Sbjct: 361 NENARPPAACPSIVNAKALGLPTSKL 386
>dbj|BAB44155.1| hydroxypyruvate reductase [Bruguiera gymnorrhiza]
          Length = 386

 Score =  495 bits (1276), Expect = e-138,   Method: Composition-based stats.
 Identities = 346/386 (89%), Positives = 369/386 (95%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP G+YRVVSTKPMPGTRWINLLV Q CR+EIC  KKTILSVEDII L+G
Sbjct: 1   MAKPVSIEVWNPRGRYRVVSTKPMPGTRWINLLVQQDCRLEICTEKKTILSVEDIIALMG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLF+ALSKAGGKAFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFAALSKAGGKAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR GLY+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGLYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQ+TRLEKFVTAYGQFLKANGEQPVTWKRA++M+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQATRLEKFVTAYGQFLKANGEQPVTWKRAATMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHL+NKE LA MKKEA+LVNCSRGPVIDE ALVEHL+ NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLINKESLASMKKEAVLVNCSRGPVIDEVALVEHLRRNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAIVVPHIASASKWTREGMATLAALNVLG++KGYP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGDPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP A PSIVNSKALGLPVSKL
Sbjct: 361 NENAPPPAACPSIVNSKALGLPVSKL 386
>gb|AAO73866.1|AF503360_1 putative NADH-dependent hydroxypyruvate reductase [Glycine max]
          Length = 386

 Score =  495 bits (1275), Expect = e-138,   Method: Composition-based stats.
 Identities = 343/386 (88%), Positives = 366/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP+GKYRVVSTKPMPGTRWINLLV    R+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPSGKYRVVSTKPMPGTRWINLLVQNDVRLEICTEKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFS LSKAGGKAFSNMAVGYNNVDV+AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEQLFSTLSKAGGKAFSNMAVGYNNVDVDAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKF+TAY  FLKA+GE PVTWKRA++M+EVL+EAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFITAYATFLKASGETPVTWKRAATMDEVLQEADII 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAIL+NCSRGPVIDEAALVEHLK+NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILINCSRGPVIDEAALVEHLKQNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG++KGYP+W D NRV+PFL
Sbjct: 301 EEPYMKPGLAELKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPVWFDANRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENA PP ASPSIVN+KALGLP SKL
Sbjct: 361 NENAQPPAASPSIVNAKALGLPTSKL 386
>emb|CAO47393.1| unnamed protein product [Vitis vinifera]
          Length = 418

 Score =  494 bits (1273), Expect = e-138,   Method: Composition-based stats.
 Identities = 343/381 (90%), Positives = 367/381 (96%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP GKYRVVSTKPMPGTRWI+LLV Q CRVEIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPCGKYRVVSTKPMPGTRWIDLLVQQDCRVEICTQKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALS+AGG+AFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSRAGGRAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLS+AAARRIVEADEFMR GLY+GWLPHLFVGNLL+GQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSMAAARRIVEADEFMRAGLYDGWLPHLFVGNLLRGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQ+TRLEKFVTAYGQFLKA+GEQPVTWKRA+SM+EVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYYDLYQATRLEKFVTAYGQFLKASGEQPVTWKRAASMDEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERL+MMKKEAIL+NCSRGPVIDE ALV HLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLSMMKKEAILINCSRGPVIDEVALVAHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG++KGYPIWHDPN+V+PFL
Sbjct: 301 DEPYMKPGLAEMKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPIWHDPNKVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGL 381
           NEN+ PP ASPSIVN+KALG 
Sbjct: 361 NENSLPPAASPSIVNAKALGS 381
>ref|NP_176968.1| HPR (HYDROXYPYRUVATE REDUCTASE); glycerate dehydrogenase/ poly(U)
           binding [Arabidopsis thaliana]
 gb|AAG52006.1|AC012563_16 hydroxypyruvate reductase (HPR); 50972-48670 [Arabidopsis thaliana]
 gb|AAK44036.1|AF370221_1 putative hydroxypyruvate reductase HPR [Arabidopsis thaliana]
 gb|AAM20404.1| hydroxypyruvate reductase (HPR) [Arabidopsis thaliana]
 gb|AAM44919.1| putative hydroxypyruvate reductase [Arabidopsis thaliana]
 gb|AAN65124.1| hydroxypyruvate reductase (HPR) [Arabidopsis thaliana]
 dbj|BAE98694.1| hydroxypyruvate reductase [Arabidopsis thaliana]
          Length = 386

 Score =  494 bits (1272), Expect = e-138,   Method: Composition-based stats.
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG
Sbjct: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL
Sbjct: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENASPPNASPSIVNSKALGLPVSKL
Sbjct: 361 NENASPPNASPSIVNSKALGLPVSKL 386
>gb|ABL10359.1| hydroxypyruvate reductase [Solenostemon scutellarioides]
          Length = 386

 Score =  494 bits (1272), Expect = e-138,   Method: Composition-based stats.
 Identities = 346/386 (89%), Positives = 366/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+ +EVYNPNGKYRVVSTK MPGTRWINLLVDQ CR+EIC  KKTILSVEDII LIG
Sbjct: 1   MAKPLQVEVYNPNGKYRVVSTKSMPGTRWINLLVDQDCRLEICTEKKTILSVEDIISLIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           +KCDGVIGQLTEDWGE LFSALS+AGG AFSNMAVGYNNVDV+AANK+G+AVGNTPGVLT
Sbjct: 61  NKCDGVIGQLTEDWGEKLFSALSRAGGTAFSNMAVGYNNVDVDAANKHGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEKFVTAYGQFL+ANGEQPVTWKRASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKFVTAYGQFLQANGEQPVTWKRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLA MKKEAILVNCSRGPVIDE ALVEHLK+NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAKMKKEAILVNCSRGPVIDEVALVEHLKQNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGL   KNAI+VPHIASASKWTREGMATLAALNVLG++KGYPIW DPN V PFL
Sbjct: 301 DEPYMKPGLEKMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPIWGDPNNVAPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NEN+ PP A PSIVNSKALGLPVSKL
Sbjct: 361 NENSPPPAACPSIVNSKALGLPVSKL 386
>dbj|BAA19751.1| hydroxypyruvate reductase [Arabidopsis thaliana]
          Length = 386

 Score =  493 bits (1271), Expect = e-138,   Method: Composition-based stats.
 Identities = 384/386 (99%), Positives = 384/386 (99%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG
Sbjct: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVI EAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIHEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           EEPFMKPGLAD KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL
Sbjct: 301 EEPFMKPGLADMKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           NENASPPNASPSIVNSKALGLPVSKL
Sbjct: 361 NENASPPNASPSIVNSKALGLPVSKL 386
>dbj|BAA08410.1| hydroxypyruvate reductase [Cucurbita cv. Kurokawa Amakuri]
          Length = 386

 Score =  492 bits (1267), Expect = e-137,   Method: Composition-based stats.
 Identities = 340/386 (88%), Positives = 364/386 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MA  V +EV+NPNGKYRVVSTKPMPGTRWINLL++Q CRVEIC  KKTILSVEDI+ LIG
Sbjct: 1   MANRVQVEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDIVALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALS+AG KAFSNMAVGYNNVDV AANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEVLFSALSRAGCKAFSNMAVGYNNVDVNAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR G Y+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGHYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEVPVTWRRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTT+HLVNKE L  MKK+AIL+NCSRGPVIDEAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAI+VPHIASASKWTREGMATLAALNVLG++K YP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKQYPVWADPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           +ENA PP ASPSIVN+KAL LPVSKL
Sbjct: 361 DENAPPPAASPSIVNAKALELPVSKL 386
>emb|CAN65023.1| hypothetical protein [Vitis vinifera]
          Length = 386

 Score =  490 bits (1263), Expect = e-137,   Method: Composition-based stats.
 Identities = 342/379 (90%), Positives = 366/379 (96%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPVSIEV+NP GKYRVVSTKPMPGTRWI+LLV Q CRVEIC  KKTILSVEDII LIG
Sbjct: 1   MAKPVSIEVWNPCGKYRVVSTKPMPGTRWIDLLVQQDCRVEICTQKKTILSVEDIIALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFSALS+AGG+AFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSALSRAGGRAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLS+AAARRIVEADEFMR GLY+GWLPHLFVGNLL+GQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSMAAARRIVEADEFMRAGLYDGWLPHLFVGNLLRGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQ+TRLEKFVTAYGQFLKA+GEQPVTWKRA+SM+EVLREADLI
Sbjct: 181 ARMMVEGFKMNLIYYDLYQATRLEKFVTAYGQFLKASGEQPVTWKRAASMDEVLREADLI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHLVNKERL+MMKKEAIL+NCSRGPVIDE ALV HLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLVNKERLSMMKKEAILINCSRGPVIDEVALVAHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLA+ KNAIVVPHIASASKWTREGMATLAALNVLG++KGYPIWHDPN+V+PFL
Sbjct: 301 DEPYMKPGLAEMKNAIVVPHIASASKWTREGMATLAALNVLGKIKGYPIWHDPNKVEPFL 360

Query: 361 NENASPPNASPSIVNSKAL 379
           NEN+ PP ASPSIVN+KAL
Sbjct: 361 NENSLPPAASPSIVNAKAL 379
>gb|ABK21250.1| unknown [Picea sitchensis]
          Length = 386

 Score =  489 bits (1259), Expect = e-136,   Method: Composition-based stats.
 Identities = 312/386 (80%), Positives = 355/386 (91%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEV+NP GK+RVVSTK MPGTRWI LL D  CR+EIC  KKTIL VEDI  LIG
Sbjct: 1   MAKPISIEVWNPAGKHRVVSTKSMPGTRWIRLLTDADCRLEICTEKKTILDVEDIQALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGETLFS L +AGG AFSNMAVGYNNVD+ AAN YGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGETLFSTLKRAGGTAFSNMAVGYNNVDLNAANTYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELA +L+++A+RR+VEAD+FMR GLY+GWLPHLFVGNLLKGQTVG+IGAGRIGSAY
Sbjct: 121 ETTAELAVALTVSASRRVVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGIIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIY+DLYQSTRLEK++TAYG+FLK+ GE PVTWKRAS+ E+VLR+AD+I
Sbjct: 181 ARMMVEGFKMNLIYYDLYQSTRLEKYMTAYGEFLKSQGEAPVTWKRASTAEDVLRDADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHP+LDKTTYHL+NK+RL++MKKEA+LVN SRGPVIDEAALV HLK NPMFRVGLDVFE
Sbjct: 241 SLHPILDKTTYHLINKDRLSIMKKEAVLVNASRGPVIDEAALVNHLKANPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLA+ KNA+VVPHIASASKWTREGMATLAALNVLG+VKGYP+W D N+++PFL
Sbjct: 301 DEPYMKPGLAEQKNAVVVPHIASASKWTREGMATLAALNVLGKVKGYPVWPDANKLEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
           +EN++PP A PSIVN+K LGL VSKL
Sbjct: 361 DENSAPPAACPSIVNAKLLGLEVSKL 386
>sp|P13443|DHGY_CUCSA Glycerate dehydrogenase (NADH-dependent hydroxypyruvate reductase)
           (HPR) (GDH)
 emb|CAA41434.1| NADH-dependent hydroxypyruvate reductase [Cucumis sativus]
 emb|CAA32764.1| unnamed protein product [Cucumis sativus]
          Length = 382

 Score =  487 bits (1254), Expect = e-136,   Method: Composition-based stats.
 Identities = 336/380 (88%), Positives = 363/380 (95%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKPV IEV+NPNGKYRVVSTKPMPGTRWINLL++Q CRVEIC  KKTILSVEDI+ LIG
Sbjct: 1   MAKPVQIEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDILALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALS+AGGKAFSNMAVGYNNVDV AANKYG+AVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEVLFSALSRAGGKAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR G Y+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGRYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEAPVTWRRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTT+HLVNKE L  MKK+AIL+NCSRGPVIDEAALV+HL++NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVDHLRDNPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAI+VPHIASASKWTREGMATLAALNVLG++KGYP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKGYPVWSDPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALG 380
           +EN SPP ASPSIVN+KALG
Sbjct: 361 DENVSPPAASPSIVNAKALG 380
>ref|NP_001045589.1| Os02g0101500 [Oryza sativa (japonica cultivar-group)]
 dbj|BAD07805.1| putative hydroxypyruvate reductase [Oryza sativa Japonica Group]
 dbj|BAD08188.1| putative hydroxypyruvate reductase [Oryza sativa Japonica Group]
 dbj|BAF07503.1| Os02g0101500 [Oryza sativa (japonica cultivar-group)]
          Length = 386

 Score =  486 bits (1253), Expect = e-135,   Method: Composition-based stats.
 Identities = 328/386 (84%), Positives = 360/386 (93%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MAKP+SIEV+NP+GKYRVVSTK MPGTRWI LL D  CR+EIC   KTILSV+DI+ LIG
Sbjct: 1   MAKPISIEVWNPSGKYRVVSTKSMPGTRWIRLLADNDCRLEICTETKTILSVDDILALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           D+CDGVIGQLTE+WGE LFSAL +AGG AFSNMAVGYNNVDVEAAN+ GIAVGNTPGVLT
Sbjct: 61  DRCDGVIGQLTEEWGEVLFSALKRAGGTAFSNMAVGYNNVDVEAANRNGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEAD+FMR GLY+GWLPHLFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADQFMRAGLYDGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMM+EGFKMNLIY+DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRA++ME+VLREAD+I
Sbjct: 181 ARMMIEGFKMNLIYYDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRAATMEDVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTTYHL+N ERLA+MKKEA+LVN SRGPVIDE ALVEHLK NPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTYHLINPERLAIMKKEAVLVNASRGPVIDEVALVEHLKANPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNA+VVPHIASASKWTREGMATLAALNVLG++KGYP+W +PN V+PFL
Sbjct: 301 DEPYMKPGLADMKNAVVVPHIASASKWTREGMATLAALNVLGKIKGYPVWGNPNLVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGLPVSKL 386
            E+A+PP A PSIVN+K LGLP SKL
Sbjct: 361 KEDATPPAACPSIVNAKQLGLPSSKL 386
>dbj|BAA08411.1| hydroxypyruvate reductase [Cucurbita cv. Kurokawa Amakuri]
          Length = 381

 Score =  485 bits (1249), Expect = e-135,   Method: Composition-based stats.
 Identities = 335/381 (87%), Positives = 360/381 (94%)

Query: 1   MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIG 60
           MA  V +EV+NPNGKYRVVSTKPMPGTRWINLL++Q CRVEIC  KKTILSVEDI+ LIG
Sbjct: 1   MANRVQVEVWNPNGKYRVVSTKPMPGTRWINLLIEQDCRVEICTEKKTILSVEDIVALIG 60

Query: 61  DKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLT 120
           DKCDGVIGQLTEDWGE LFSALS+AG KAFSNMAVGYNNVDV AANKYGIAVGNTPGVLT
Sbjct: 61  DKCDGVIGQLTEDWGEVLFSALSRAGCKAFSNMAVGYNNVDVNAANKYGIAVGNTPGVLT 120

Query: 121 ETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAY 180
           ETTAELAASLSLAAARRIVEADEFMR G Y+GWLP+LFVGNLLKGQTVGVIGAGRIGSAY
Sbjct: 121 ETTAELAASLSLAAARRIVEADEFMRAGHYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAY 180

Query: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLI 240
           ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYG+FLKANGE PVTW+RASSM+EVLREAD+I
Sbjct: 181 ARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGEFLKANGEVPVTWRRASSMDEVLREADVI 240

Query: 241 SLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300
           SLHPVLDKTT+HLVNKE L  MKK+AIL+NCSRGPVIDEAALVEHLKENPMFRVGLDVFE
Sbjct: 241 SLHPVLDKTTFHLVNKESLKAMKKDAILINCSRGPVIDEAALVEHLKENPMFRVGLDVFE 300

Query: 301 EEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
           +EP+MKPGLAD KNAI+VPHIASASKWTREGMATLAALNVLG++K YP+W DPNRV+PFL
Sbjct: 301 DEPYMKPGLADMKNAIIVPHIASASKWTREGMATLAALNVLGKIKQYPVWADPNRVEPFL 360

Query: 361 NENASPPNASPSIVNSKALGL 381
           +ENA PP ASPSIVN+KALG+
Sbjct: 361 DENAPPPAASPSIVNAKALGI 381
>ref|YP_001471315.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Thermotoga lettingae TMO]
 gb|ABV34251.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Thermotoga lettingae TMO]
          Length = 327

 Score =  479 bits (1234), Expect = e-133,   Method: Composition-based stats.
 Identities = 139/351 (39%), Positives = 201/351 (57%), Gaps = 26/351 (7%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
            K +V  T  +P       ++ Q C ++I +    +L  + +ID +    DG++  L + 
Sbjct: 2   KKPKVFVTAQIPDEGLK--MISQHCEMQIGNY-DGVLPKDVLIDKVKG-VDGILCLLADV 57

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
             + +  A  K   K  +N AVGYNN+D+E A K GI V NTPGVLTETTA+LA +L ++
Sbjct: 58  IDKDVMEAAGK-QLKVIANYAVGYNNIDIEEATKRGIMVTNTPGVLTETTADLAWALMMS 116

Query: 134 AARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
            ARRIVE+D+F+R G + GW P L +G  + G T+GV+G GRIG A AR    GF M ++
Sbjct: 117 IARRIVESDKFVREGKFNGWQPMLMLGTDIYGATLGVVGFGRIGQAVARR-ASGFNMRVL 175

Query: 194 YFDLYQSTR-LEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYH 252
           Y+   ++   +EK + A                    +  +LRE+D ++LH  L K TYH
Sbjct: 176 YYSRKRAPEDVEKQLNAS----------------FVDLSTLLRESDFVTLHLPLTKETYH 219

Query: 253 LVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADT 312
           L+ +E L MMKKEA L+N +RGPVIDE ALV+ LK   +    LDVFE+EP ++P L + 
Sbjct: 220 LIGEEELRMMKKEAYLINTARGPVIDEKALVKALKNKWIRGAALDVFEKEPQIEPELLEL 279

Query: 313 KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNEN 363
            N I+ PHI SAS  TR  M+ +AA N++  + G      PN V+  + + 
Sbjct: 280 DNVILTPHIGSASYTTRTKMSVMAAENLVKALYGEI---PPNLVNTEVLKK 327
>ref|ZP_01368724.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Desulfitobacterium hafniense DCB-2]
 gb|EAT52306.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Desulfitobacterium hafniense DCB-2]
          Length = 334

 Score =  478 bits (1232), Expect = e-133,   Method: Composition-based stats.
 Identities = 120/348 (34%), Positives = 185/348 (53%), Gaps = 26/348 (7%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K RV  T+ +P       L+++ C V++   + T +    +   I  + DG+   LTE  
Sbjct: 8   KPRVFITRKIPEDILT--LIEEVCEVKVWPEEDTPIPRSVLEQEIR-EVDGLYCLLTETI 64

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
             +L         K  SNMAVGYNN+D+EAA +  I V NTPGVLTETTA+L  +L +  
Sbjct: 65  DASLLDLGKNL--KVVSNMAVGYNNIDIEAATQRNILVTNTPGVLTETTADLTFALLMMT 122

Query: 135 ARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIY 194
           ARR+ E+ +++R G ++ W P L  G  + G T+G++G GRIG A  +   +GF M +IY
Sbjct: 123 ARRMEESSQYLRQGHWKTWSPMLLAGQDIFGATLGIVGMGRIGEALVKR-AKGFDMKIIY 181

Query: 195 FDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
           ++      LE+ +                     S++E+L+EAD + +       T +L+
Sbjct: 182 YNRTPKPELEESLG----------------IEYRSLDELLQEADFVCILTPYTPETRNLI 225

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFM-KPGLADTK 313
            K  L +MK  +IL+N +RG +++E  L E L +  ++  GLDVFE+EP      L    
Sbjct: 226 GKRELELMKPTSILINTARGGIVNEEDLYEALAQQKIYAAGLDVFEQEPLPTDHPLLTLT 285

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
           N + +PHI SA+  TR  MA LAA N+L  ++G      P+ V+P + 
Sbjct: 286 NCVALPHIGSATVKTRREMARLAAQNLLAYLQGQ---RPPHCVNPSVL 330
>ref|NP_422516.1| 2-hydroxyacid dehydrogenase [Caulobacter crescentus CB15]
 gb|AAK25684.1| D-isomer specific 2-hydroxyacid dehydrogenases family protein
           [Caulobacter crescentus CB15]
          Length = 344

 Score =  474 bits (1220), Expect = e-132,   Method: Composition-based stats.
 Identities = 106/350 (30%), Positives = 177/350 (50%), Gaps = 23/350 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
              K +V+ T+ +P    +   + +    E+ ++    ++ ++++D +  + D ++  +T
Sbjct: 18  AARKLKVIVTRKLPDP--VETRMCELFDTEL-NVSDKPMTADELVDAMS-RADVLVPTIT 73

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     L S       K  +N   G +N+DV  AN  GI V NTPGVLTE TA+L  +L 
Sbjct: 74  DRIDSRLLSRSGD-RLKLIANFGAGVDNIDVATANARGIIVTNTPGVLTEDTADLTMTLI 132

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           +AA+RRIVE  E ++ G + GW P   +G  L G+ +G+IG GRIG A AR   + F M 
Sbjct: 133 MAASRRIVEGAEVVKAGGFHGWSPTWMMGRRLWGKRLGIIGMGRIGQAVARR-AKAFGMQ 191

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +                 +     + +      S++++L   D +S++      TY
Sbjct: 192 VHYHNRKP--------------VSPRIAEELGCTYWESLDQMLARMDFVSVNCPHTPATY 237

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL++  RL +++  A++VN +RG VIDE AL   L +  +   GLDV+E EP + P L  
Sbjct: 238 HLLSARRLKLLRPHAVVVNTARGEVIDEGALANMLAKGEIAGAGLDVYEHEPAINPKLLK 297

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
             N +++PH+ SA+   R  M     +NV   + G+     P+RV P + 
Sbjct: 298 LPNVVLLPHMGSATVEGRIDMGEKVIVNVKTFMDGH---RPPDRVIPAML 344
>ref|YP_419558.1| Lactate dehydrogenase and related dehydrogenase [Magnetospirillum
           magneticum AMB-1]
 dbj|BAE48999.1| Lactate dehydrogenase and related dehydrogenase [Magnetospirillum
           magneticum AMB-1]
          Length = 358

 Score =  473 bits (1218), Expect = e-131,   Method: Composition-based stats.
 Identities = 97/350 (27%), Positives = 174/350 (49%), Gaps = 23/350 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P+ K  VV ++ +P      ++     R+ +       ++  ++I+ +    D ++  +T
Sbjct: 32  PSKKPVVVVSRKLPDVIETRMMELFDTRLNV---DDHPMTKTELIEAVK-IADVLVPTVT 87

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     + S       K  +N   G +++D+  A + GI V NTPGVLTE TA++A +L 
Sbjct: 88  DRIDAGILSQA-GPNLKLVANFGTGVDHIDLATARQRGITVTNTPGVLTEDTADMAMALI 146

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           ++  RRI E +  +R G ++GW P   +G+ + G+ +G+IG GRIG A AR   + F M+
Sbjct: 147 MSVPRRIAEGERLIRSGDWKGWSPTFMLGHRIWGKRLGIIGMGRIGQAVARR-AKAFGMS 205

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +  +              +  + E  +      S++++L   D++++H      T+
Sbjct: 206 IHYHNRKR--------------VHPDIETELEATYWESLDQMLARMDVVTVHCPHTPATF 251

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL++  RL ++ K A +VN +RG ++DE AL   L    +   GLDVFE EP + P L  
Sbjct: 252 HLLSARRLELLPKHAYVVNTARGEIVDENALTRMLIRGDLAGAGLDVFEHEPAVNPKLLA 311

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
             N +++PH+ SA+   R  M     +N+     G+     P+RV   + 
Sbjct: 312 LDNVVLLPHLGSATIEGRVDMGEKVLVNIKTFADGH---QPPDRVLASMF 358
>ref|ZP_01666395.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermosinus carboxydivorans Nor1]
 gb|EAX47745.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Thermosinus carboxydivorans Nor1]
          Length = 327

 Score =  472 bits (1217), Expect = e-131,   Method: Composition-based stats.
 Identities = 133/342 (38%), Positives = 194/342 (56%), Gaps = 25/342 (7%)

Query: 18  VVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWGET 77
           V  T+ +P T    L   Q C VE+ + +  +L+ ++++  +  + D V+  LT+   + 
Sbjct: 6   VYVTRRIPDTALDVLR--QRCNVEV-NPEDRVLTRDELLAKVTGR-DAVLCLLTDTIDDA 61

Query: 78  LFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARR 137
           + +A  K   + F+N AVGYNN+DV AA K GI + NTP VLT  TA++A +L  A ARR
Sbjct: 62  VLAAAGK-QCRIFANYAVGYNNIDVAAATKRGIFISNTPDVLTAATADMAWALLFAVARR 120

Query: 138 IVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDL 197
           +VE D+F R G + GW P L +G  + G+TVG+IGAGRIG+A+AR   +GF M ++Y   
Sbjct: 121 VVEGDKFTRAGKFHGWGPLLMLGQEVTGKTVGIIGAGRIGAAFARR-AKGFDMKILYTGR 179

Query: 198 YQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKE 257
            +    E+   A                     + +LREAD ISLH  L   TYHL+ + 
Sbjct: 180 SRKPDFERETGA----------------TYVDFDTLLREADFISLHVPLTPETYHLIGER 223

Query: 258 RLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIV 317
            L +MK  AIL+N +RGPV+DE ALV  L+   ++  GLDVFE EP +  GLA+  N ++
Sbjct: 224 ELKLMKPTAILINTARGPVVDEKALVAALRRGEIWGAGLDVFENEPALAEGLAELDNVVI 283

Query: 318 VPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPF 359
            PH+ SA+  TR  M  +A  N+L  + G      PN ++P 
Sbjct: 284 PPHLGSATLETRTKMGLVAVENILAALDGR---MPPNCLNPE 322
>ref|YP_517906.1| hypothetical protein DSY1673 [Desulfitobacterium hafniense Y51]
 dbj|BAE83462.1| hypothetical protein [Desulfitobacterium hafniense Y51]
          Length = 334

 Score =  472 bits (1217), Expect = e-131,   Method: Composition-based stats.
 Identities = 118/348 (33%), Positives = 184/348 (52%), Gaps = 26/348 (7%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K RV  T+ +P       L+++ C V++   + T +    +   I  + DG+   LTE  
Sbjct: 8   KPRVFITRKIPEDILT--LIEEVCEVKVWPEEDTPIPRSVLEQEIR-EVDGLYCLLTETI 64

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
             +L         K  SNMAVGYNN+D+EAA +  I V NTPGVLTETTA+L  +L +  
Sbjct: 65  DASLLDLGKNL--KVVSNMAVGYNNIDIEAATQRNILVTNTPGVLTETTADLTFALLMMT 122

Query: 135 ARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIY 194
           ARR+ E+ +++R G ++ W P L  G  + G T+G++G GRIG A  +   +GF M +IY
Sbjct: 123 ARRMEESSQYLRQGHWKTWSPMLLAGQDIFGATLGIVGMGRIGEALVKR-AKGFDMKIIY 181

Query: 195 FDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
           ++      LE+ +                      ++E+L+EAD + +       T +L+
Sbjct: 182 YNRTPKPELEESLG----------------IEYRLLDELLQEADFVCILTPYTPETRNLI 225

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFM-KPGLADTK 313
            K  L +MK  +IL+N +RG +++E  L E L +  ++  GLDVF++EP      L    
Sbjct: 226 GKRELELMKPTSILINTARGGIVNEEDLYEALAQQQIYAAGLDVFDQEPLPTDHPLLTLT 285

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
           N + +PHI SA+  TR  MA LAA N+L  ++G      P+ V+P + 
Sbjct: 286 NCVALPHIGSATIKTRREMARLAAQNLLTYLQGQ---RPPHCVNPSVL 330
>ref|NP_578048.1| glyoxylate reductase [Pyrococcus furiosus DSM 3638]
 sp|Q8U3Y2|GYAR_PYRFU Glyoxylate reductase (Glycolate reductase)
 gb|AAL80443.1| putative phosphoglycerate dehydrogenase [Pyrococcus furiosus DSM
           3638]
          Length = 336

 Score =  472 bits (1215), Expect = e-131,   Method: Composition-based stats.
 Identities = 123/356 (34%), Positives = 189/356 (53%), Gaps = 30/356 (8%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K +V  T+ +P      L  +          ++  +  E +++ + D  D ++  L+E  
Sbjct: 2   KPKVFITRAIPENGINMLEEEFE---VEVWEEEREIPREKLLEKVKD-VDALVTMLSERI 57

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
            + +F        +  +N AVGY+N+DVE A + GI V NTP VLT  TA+ A +L LA 
Sbjct: 58  DQEVFENAP--RLRIVANYAVGYDNIDVEEATRRGIYVTNTPDVLTNATADHAFALLLAT 115

Query: 135 ARRIVEADEFMRGGLYEG----WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKM 190
           AR +V+ D+F+R G ++     W P  F+G  L G+T+G++G GRIG A AR   +GF M
Sbjct: 116 ARHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARR-AKGFNM 174

Query: 191 NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTT 250
            ++Y+   + ++ EK + A                    +EEVL+E+D + L   L K T
Sbjct: 175 RILYYSRTRKSQAEKELGA----------------EYRPLEEVLKESDFVILAVPLTKET 218

Query: 251 YHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLA 310
            +++N+ERL +MK  AILVN +RG V+D  AL++ LKE  +   GLDVFEEEP+    L 
Sbjct: 219 MYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPYYNEELF 278

Query: 311 DTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASP 366
              N ++ PHI SA+   RE MA L A N++   +G      P  V+  + +   P
Sbjct: 279 SLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRGEI---PPTLVNKEVIKIRKP 331
>ref|YP_001686676.1| Glyoxylate reductase [Caulobacter sp. K31]
 gb|ABZ74178.1| Glyoxylate reductase [Caulobacter sp. K31]
          Length = 328

 Score =  471 bits (1212), Expect = e-131,   Method: Composition-based stats.
 Identities = 105/349 (30%), Positives = 178/349 (51%), Gaps = 23/349 (6%)

Query: 13  NGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTE 72
             K +V+ T+ +P    +   + +    ++ ++    L+ +++++ + ++ D ++  +T+
Sbjct: 3   ARKLKVIVTRKLPDP--VETRMCELFDTQL-NVTDKPLTADELVEAM-NEADVLVPTITD 58

Query: 73  DWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSL 132
                L S       K  +N   G +N+DV  AN  GI V NTPGVLTE TA+L  +L +
Sbjct: 59  RIDSRLLSRAGD-RLKLIANFGAGVDNIDVATANARGIIVTNTPGVLTEDTADLTMTLIM 117

Query: 133 AAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNL 192
           AA+RR+VE  E ++ G + GW P   +G  L G+ +G+IG GRIG A AR   + F M +
Sbjct: 118 AASRRVVEGAEVVKAGGFHGWSPTWMLGRRLWGKRLGIIGMGRIGQAVARR-AKAFGMQV 176

Query: 193 IYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYH 252
            Y +                 +     + +      S++++L   D+IS++      TYH
Sbjct: 177 HYHNRKP--------------VSPRIAEELGCTYWESLDQMLARMDIISVNCPHTPATYH 222

Query: 253 LVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADT 312
           L++  RL +++ + I+VN +RG VIDE AL   L    +   GLDV+E EP + P L   
Sbjct: 223 LLSARRLKLLRPQTIIVNTARGEVIDEGALANMLARGEIAGAGLDVYEHEPAINPKLLKL 282

Query: 313 KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
            N +++PH+ SA+   R  M     +NV   + G+     P+RV P + 
Sbjct: 283 PNVVLLPHMGSATVEGRIDMGEKVIVNVKTFMDGH---RPPDRVIPSML 328
>ref|ZP_00054933.1| COG1052: Lactate dehydrogenase and related dehydrogenases
           [Magnetospirillum magnetotacticum MS-1]
          Length = 328

 Score =  470 bits (1210), Expect = e-130,   Method: Composition-based stats.
 Identities = 100/350 (28%), Positives = 173/350 (49%), Gaps = 23/350 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           PN K  VV ++ +P      ++     R+ +       +S  ++I+ +    D ++  +T
Sbjct: 2   PNKKPVVVVSRKLPDVIETRMMELFDTRLNV---DDHPMSKMELIEAVK-IADVLVPTVT 57

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     + S       K  +N   G +++D+  A   GI V NTPGVLTE TA++A +L 
Sbjct: 58  DRIDAGVLSQA-GPNLKLIANFGTGVDHIDLATARSRGIIVTNTPGVLTEDTADMAMALI 116

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           ++  RRI E +  +R G ++GW P   +G+ + G+ +G+IG GRIG A AR   + F M+
Sbjct: 117 MSVPRRIAEGERLIRSGDWKGWSPTFMLGHRIWGKRLGIIGMGRIGQAVARR-AKAFGMS 175

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +  +              +  + E  +      S++++L   D+I++H      T+
Sbjct: 176 IHYHNRKR--------------VHPDIETELEATYWESLDQMLARMDVITVHCPHTPATF 221

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL++  RL ++ K A +VN +RG ++DE AL   L    +   GLDVFE EP + P L  
Sbjct: 222 HLLSARRLELLPKHAYVVNTARGEIVDENALTRMLIRGDLAGAGLDVFEHEPAVNPKLLA 281

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
             N +++PH+ SA+   R  M     +N+     G+     P+RV   + 
Sbjct: 282 LDNVVLLPHLGSATIEGRVDMGEKVLVNIKTFADGH---QPPDRVLASMF 328
>ref|ZP_01548851.1| 2-hydroxyacid dehydrogenase [Stappia aggregata IAM 12614]
 gb|EAV42768.1| 2-hydroxyacid dehydrogenase [Stappia aggregata IAM 12614]
          Length = 328

 Score =  469 bits (1209), Expect = e-130,   Method: Composition-based stats.
 Identities = 103/348 (29%), Positives = 178/348 (51%), Gaps = 23/348 (6%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
            K  VV T+ +P    +   + +     + +      S  ++++ +    D ++  +T+ 
Sbjct: 4   KKPVVVVTRKLPD--VVETRMRELFETRL-NDNDRPFSQAELVEAVRT-ADVLVPTVTDR 59

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
              ++ S   +   K  +N   G +N+DV +AN  GI V NTPGVLTE TA++  +L LA
Sbjct: 60  IDSSVLSQAGE-NLKLIANFGNGVDNIDVVSANNRGINVTNTPGVLTEDTADMTMALILA 118

Query: 134 AARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
             RR+    + +  G + GW P   +G+ + G+ +G+IG GRIG A AR   + F M++ 
Sbjct: 119 VPRRLATGIKALEAGDWAGWSPTWMLGHRIWGKRLGIIGMGRIGQAVARR-AKAFGMSIH 177

Query: 194 YFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHL 253
           Y +  +                 + E+ +      S++++L   D++S+H      T+HL
Sbjct: 178 YHNRRRLAE--------------SVEEELEATYWDSLDQMLARMDVVSIHCPHTPGTFHL 223

Query: 254 VNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTK 313
           ++  RL ++KK+A +VN +RG VIDE AL+  L+   +   GLDVFE EP + P LA  +
Sbjct: 224 LSARRLKLLKKDAYVVNTARGEVIDENALIRMLESGELAGAGLDVFEHEPAVNPKLAKLE 283

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
           N +++PH+ SA+   R  M     +N+   + G+     P+RV P + 
Sbjct: 284 NVLLLPHMGSATIEGRIEMGEKVIINIKTFMDGH---RPPDRVLPSML 328
>ref|YP_001410651.1| Glyoxylate reductase [Fervidobacterium nodosum Rt17-B1]
 gb|ABS60994.1| Glyoxylate reductase [Fervidobacterium nodosum Rt17-B1]
          Length = 317

 Score =  469 bits (1207), Expect = e-130,   Method: Composition-based stats.
 Identities = 142/342 (41%), Positives = 202/342 (59%), Gaps = 27/342 (7%)

Query: 16  YRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWG 75
            RV  T  +P       ++ +   V++   ++  LS E++I    +  D ++ QL +   
Sbjct: 1   MRVFVTYAIPEKGIN--MLKERFEVDVYTGEE-FLSKEEMIKR-AEYADAIVTQLRDPID 56

Query: 76  ETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAA 135
           +    +L KA  K  +N AVGYNN+D+EAA + GI V NTPGVLTE TA++A +L LA A
Sbjct: 57  KEFIYSLKKA--KIIANYAVGYNNIDIEAAKERGIYVTNTPGVLTEATADIAFALILAVA 114

Query: 136 RRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYF 195
           RRIVE+D+F+R G + GW P LF+G  L G+T+GVIG GRIG A AR    GF MN++Y+
Sbjct: 115 RRIVESDKFVREGKFVGWKPKLFLGYDLYGKTLGVIGMGRIGQAVARR-ALGFGMNIVYY 173

Query: 196 DLYQSTR-LEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLV 254
           +  +    +EK   A                +  +++E++  +D ISLH  L K TYHL+
Sbjct: 174 NRNRLPEEIEKQYNA----------------KYVNIDELVEISDYISLHTPLTKETYHLI 217

Query: 255 NKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKN 314
           NKER+A MK  AILVN +RGPV+DE AL E LKE  +   G DV+E EP + PGL    N
Sbjct: 218 NKERIAKMKPNAILVNTARGPVVDEQALYEALKERRIAGAGFDVYENEPVLTPGLEKLDN 277

Query: 315 AIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRV 356
            +++PHI SA+  TR+ M+ + A+NV+  + G       N V
Sbjct: 278 VVLLPHIGSATYETRDKMSEIVAINVMEALDGK---RPSNCV 316
>ref|YP_762106.1| glyoxylate reductase [Hyphomonas neptunium ATCC 15444]
 gb|ABI76968.1| glyoxylate reductase [Hyphomonas neptunium ATCC 15444]
          Length = 328

 Score =  465 bits (1199), Expect = e-129,   Method: Composition-based stats.
 Identities = 106/350 (30%), Positives = 174/350 (49%), Gaps = 23/350 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P  K +VV T+ +P    + L + +     + +      SVE++   +    D ++  +T
Sbjct: 2   PASKLKVVVTRKLPAP--VELRMKELFDARL-NESDRPFSVEELAQAMQT-ADVLVPTVT 57

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     L +       +  +    G +N+DV +A + GI V NTPGVLT+ TA++A +L 
Sbjct: 58  DKIDGRLMARAGD-QLRLIAQFGAGVDNIDVASAVQRGITVTNTPGVLTDDTADVAMALI 116

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           LA  RR+ E  + M  G ++GW P   +G  L G+ +G+IG GRIG A AR     F M 
Sbjct: 117 LAVPRRMHEGVQIMEAGKFDGWTPTWMMGRRLSGKRLGIIGMGRIGQAVARR-ARAFGMQ 175

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +                 + +  E+ +      S++++L   D++S++      T+
Sbjct: 176 IHYHNRKP--------------VSSRIEESLEATYWDSLDQMLARMDIVSINCPHTPATF 221

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N  RL +MK EA ++N +RG VIDEAAL   ++   +   GLDVFE EP + P L  
Sbjct: 222 HLINARRLGLMKPEAYIINTARGEVIDEAALARAIRAGKIAGAGLDVFEREPAVNPELIG 281

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
             N +++PH+ SA+   R  M     +N+     G+     P+RV P + 
Sbjct: 282 LPNVLLLPHMGSATIEGRTEMGEKVIINIKTFADGH---RPPDRVIPAIL 328
>ref|YP_001737977.1| Glyoxylate reductase [Candidatus Korarchaeum cryptofilum OPF8]
 gb|ACB08294.1| Glyoxylate reductase [Candidatus Korarchaeum cryptofilum OPF8]
          Length = 332

 Score =  465 bits (1198), Expect = e-129,   Method: Composition-based stats.
 Identities = 130/354 (36%), Positives = 199/354 (56%), Gaps = 28/354 (7%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K RV  T+ +P      +  ++   +++    +   S + II+ + D CD ++  LT+  
Sbjct: 2   KPRVFVTREIPERGLSKI--EEHFELDLW-KDEAPPSKKVIIERVKD-CDALVSLLTDPI 57

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
              +F A  K   +  +  AVGY+N+DV+ A K GI V NTPGVLTETTA+ A +L +AA
Sbjct: 58  DAEVFEAAPKL--RIVAQYAVGYDNIDVKEATKRGIYVTNTPGVLTETTADFAFALLMAA 115

Query: 135 ARRIVEADEFMRGGLYE-GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
           ARR+VEAD ++R G ++  W P + +G  + G+T+G++G GRIG+A AR   +GF M ++
Sbjct: 116 ARRVVEADRYVREGKWKVAWHPMMMLGYDVYGRTLGIVGMGRIGAAVARR-AKGFGMRIL 174

Query: 194 YFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHL 253
           Y+D  +    EK +                      +E++L E+D +SLH  L + TYH+
Sbjct: 175 YYDSIRREDFEKELG----------------VEYVPLEKLLEESDFVSLHVPLTEETYHM 218

Query: 254 VNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPF-MKPGLADT 312
           + +E+L  MK+ AILVN SRG V+D+ AL + LKE  +   GLDVFE+EP      L   
Sbjct: 219 IGEEQLRRMKRTAILVNTSRGKVVDQKALYKALKEGWIAGAGLDVFEQEPIPPDDPLLKL 278

Query: 313 KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASP 366
           +N ++ PH ASAS  TR  MA + A N++   +G      PN V+  + +   P
Sbjct: 279 ENVVLAPHAASASHETRSRMAEMVAENLIAFKRGEI---PPNLVNQEVVKVRPP 329
>ref|YP_113865.1| 2-hydroxyacid dehydrogenase [Methylococcus capsulatus str. Bath]
 gb|AAU92321.1| D-isomer specific 2-hydroxyacid dehydrogenase family protein
           [Methylococcus capsulatus str. Bath]
          Length = 323

 Score =  465 bits (1198), Expect = e-129,   Method: Composition-based stats.
 Identities = 104/336 (30%), Positives = 171/336 (50%), Gaps = 19/336 (5%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
            K +V+ T+  P +    L         + +     +S +++   + D  D V+  +T+ 
Sbjct: 2   SKPKVLVTRRWPESCESRLRESFHV---VFNADDHPMSRDELKAALRDY-DAVLPTVTDA 57

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
               + S       K   N  VG+N++D++ A + GIAV NTP VLT+ TA++A  L LA
Sbjct: 58  IDADVLSVEP-LRCKILGNFGVGFNHIDLDTARQRGIAVTNTPDVLTDCTADIAMLLMLA 116

Query: 134 AARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
            ARR  E +  +R G + GW P   +G  + G+ +G++G GRI  A A+    GF M +I
Sbjct: 117 VARRGGEGEREVRSGRWTGWRPTHMLGTKVTGKILGLVGFGRIARAMAKKAHFGFDMPVI 176

Query: 194 YFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHL 253
           ++D +   +              +    +  ++  ++EEVL  AD ++LH    K   HL
Sbjct: 177 FYDPFPPPQ--------------DLIDALGAEQCGTLEEVLERADFVALHCPGSKENRHL 222

Query: 254 VNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTK 313
           +N +RLA MK ++ LVN +RG V+D  AL++ L+   +   GLDV+E EP + PG  +  
Sbjct: 223 INADRLARMKPQSYLVNTARGDVVDNEALIQALRNRRIRGAGLDVYEGEPRLNPGFLELD 282

Query: 314 NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPI 349
           N ++ PH+ SA++ TR  M      N+    +G P 
Sbjct: 283 NVVLFPHLGSATEETRIAMGMRVIDNITAFFEGRPP 318
>ref|YP_183096.1| glyoxylate reductase [Thermococcus kodakarensis KOD1]
 sp|Q5JEZ2|GYAR_PYRKO Glyoxylate reductase (Glycolate reductase)
 dbj|BAD84872.1| glyoxylate reductase [Thermococcus kodakarensis KOD1]
          Length = 333

 Score =  465 bits (1197), Expect = e-129,   Method: Composition-based stats.
 Identities = 127/356 (35%), Positives = 193/356 (54%), Gaps = 30/356 (8%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           + +V  T+ +P       ++ +   VE+   ++  +  E ++  + D  D ++  L+E  
Sbjct: 2   RPKVFITRAIPENGI--EMLKEHFEVEVW-PEEREIPREVLLKKVRD-VDALVTMLSERI 57

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
              +F A      +  +N AVGY+N+DVE A + GI V NTP VLT+ TA+ A +L LA 
Sbjct: 58  DSEVFDAAP--RLRIVANYAVGYDNIDVEEATRRGIYVTNTPDVLTDATADFAWTLLLAT 115

Query: 135 ARRIVEADEFMRGGLYEG----WLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKM 190
           ARR++EAD F R G ++     W P  F+G  + G+T+G++G GRIG A AR    GF M
Sbjct: 116 ARRLIEADHFTRSGEWKRRGIAWHPRWFLGYDVYGKTIGIVGFGRIGQAVARR-ARGFGM 174

Query: 191 NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTT 250
            ++Y+   +    EK + A                   S+E++LRE+D + L   L K T
Sbjct: 175 RILYYSRSRKPEAEKELGA----------------EFRSLEDLLRESDFVVLAVPLTKET 218

Query: 251 YHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLA 310
            +++N+ERL +MKK AILVN +RG V+D  AL++ LKE  +   GLDV+EEEP+    L 
Sbjct: 219 QYMINEERLRLMKKTAILVNIARGKVVDTKALMKALKEGWIAGAGLDVYEEEPYYNEELF 278

Query: 311 DTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASP 366
             KN ++ PHI SA+   REGMA L A N++    G      P  V+  + +   P
Sbjct: 279 SLKNVVLAPHIGSATYGAREGMAELVARNLIAFKNGEV---PPTLVNKEVVKVRKP 331
>ref|ZP_02913953.1| Glyoxylate reductase [Geobacillus sp. WCH70]
 gb|EDT34934.1| Glyoxylate reductase [Geobacillus sp. WCH70]
          Length = 327

 Score =  465 bits (1197), Expect = e-129,   Method: Composition-based stats.
 Identities = 117/351 (33%), Positives = 177/351 (50%), Gaps = 26/351 (7%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
           G+  V  T+ +P      +       V +       +S + +I+    K D ++  +++ 
Sbjct: 2   GRPYVFITRKLPDDIIAPI--KDIAEVAMWPHDDIPVSRDVLINEAK-KADALLTMVSDV 58

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
             + +  A      K  +NM VG++N+DV AA KYGIAV NTP VLT+TTA+L  +L LA
Sbjct: 59  IDQEVLKAGK--SLKVVANMGVGFDNIDVPAATKYGIAVCNTPDVLTDTTADLTFALLLA 116

Query: 134 AARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
            ARRIVEA +F++ G ++ W P L  G  +  +T+G++G G+IG A A+    GF MN++
Sbjct: 117 TARRIVEAAQFIKEGKWKSWSPFLLAGVDVHHKTIGIVGMGKIGQAVAKRAA-GFDMNIL 175

Query: 194 YFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHL 253
           Y +  ++   EK + A                   S +E+L  AD +     L   T H+
Sbjct: 176 YHNRSRNIEAEKQLGA----------------TYCSFQELLATADFVVCLTPLTNETRHM 219

Query: 254 VNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPF-MKPGLADT 312
            N+E    MK+ AI +N SRG V+DE AL + L    +   GLDVFE EP      L   
Sbjct: 220 FNREAFRKMKQSAIFINASRGAVVDEQALYDALVSGEIAGAGLDVFEHEPIDASHPLLTL 279

Query: 313 KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNEN 363
           KN + +PHI SA+  TR  M  LA+ N++  ++G         V+   N  
Sbjct: 280 KNVVALPHIGSATGETRTKMMELASRNIIAVLQGK---QPETLVNKEWNSR 327
>ref|YP_001534304.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Dinoroseobacter shibae DFL 12]
 gb|ABV94703.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding
           [Dinoroseobacter shibae DFL 12]
          Length = 328

 Score =  463 bits (1192), Expect = e-128,   Method: Composition-based stats.
 Identities = 101/350 (28%), Positives = 174/350 (49%), Gaps = 23/350 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P  +  VV T+ +P    +   + +   VE+ +   T +S + +   +  + D ++  ++
Sbjct: 2   PGERLSVVVTRRLPEA--VETRLKELFDVEL-NESDTPMSRDALQAAMR-RADVLVPTVS 57

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     + + +     K  +N   G +++DV  A + GI V NTPGVLT+ TA++  +L 
Sbjct: 58  DHIDGAMLAGVGD-RLKLIANYGAGVDHIDVATARQRGIHVSNTPGVLTDDTADMTLALI 116

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           LA  RRI E    M+ G + GW P   +G  + G+ +G++G GRIG A AR   + F M 
Sbjct: 117 LAVTRRIPEGLALMQTGAWTGWSPTALMGGRIAGRRLGILGMGRIGQAVARR-AKAFGMQ 175

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +  +              L    E+ +      S+++++   D+IS++     +T+
Sbjct: 176 IHYHNRRR--------------LHKGIEEELEATWWESLDQMVSRMDVISVNCPHTPSTF 221

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N  RL +MK  A++VN SRG VIDE AL   L+   +   GLDVFE    + P L +
Sbjct: 222 HLMNARRLKLMKPSAVIVNTSRGEVIDENALTRMLRAGDIAGAGLDVFEHGHEVNPRLRE 281

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
             N +++PH+ SA++  R  M     +N+     G+     P+ V P + 
Sbjct: 282 LPNVVLLPHMGSATEEGRAEMGEKVIINIKTFDDGH---RPPDLVVPSML 328
>ref|ZP_01861538.1| 2-hydroxyacid dehydrogenase [Bacillus sp. SG-1]
 gb|EDL63413.1| 2-hydroxyacid dehydrogenase [Bacillus sp. SG-1]
          Length = 351

 Score =  462 bits (1190), Expect = e-128,   Method: Composition-based stats.
 Identities = 112/351 (31%), Positives = 182/351 (51%), Gaps = 26/351 (7%)

Query: 13  NGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTE 72
             K  V  T+ +P     +L   +   VE+   +   +  E +++    +  G++  L++
Sbjct: 26  GMKPYVYVTRKLPEEVLTSL--QEKYEVEMWDDENIAVPREILLEK-AGEASGILSMLSD 82

Query: 73  DWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSL 132
                LF        K  +N+AVG++N+D++AAN+  +AV NTP VLT+TTA+L   L +
Sbjct: 83  PIDRELFEKSPNL--KVVANLAVGFDNIDLKAANEKDVAVCNTPDVLTDTTADLTFGLMM 140

Query: 133 AAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNL 192
           AAARR++EAD+++R G ++ W P L  G  +  +TVG+IG G IG A+AR   +GF MN+
Sbjct: 141 AAARRLIEADKYVREGKWKSWSPLLMAGTDIHHKTVGIIGMGSIGEAFARR-AKGFDMNI 199

Query: 193 IYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYH 252
           +Y +  +    E+ + A                + +S+EE+L ++D +     L   T  
Sbjct: 200 LYHNRSRKPEAEEVLGA----------------KYASLEELLSQSDYVVCLAPLTPETKG 243

Query: 253 LVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPF-MKPGLAD 311
           L+ KE+  MMK  AI +N +RGP+++E AL   L +  +   GLDVFE+EP      L  
Sbjct: 244 LLQKEQFEMMKSSAIFINAARGPIVNEEALYRALVDGEIAAAGLDVFEKEPIDKTHPLLS 303

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNE 362
             N + +PHI S+S  TR  M  L   N+   ++G         V+    +
Sbjct: 304 LDNVVALPHIGSSSVETRMEMMELCISNIKAVLEG---GTPKTLVNKEWQK 351
>sp|Q9C4M5|GYAR_THELI Glyoxylate reductase (Glycolate reductase)
 dbj|BAB40320.1| glyoxylate reductase [Thermococcus litoralis]
          Length = 331

 Score =  462 bits (1189), Expect = e-128,   Method: Composition-based stats.
 Identities = 133/356 (37%), Positives = 198/356 (55%), Gaps = 30/356 (8%)

Query: 15  KYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDW 74
           K +V  T+ +P       ++++   +E+    K       +++ +  + D ++  +T+  
Sbjct: 2   KPKVFITRQIPENGIK--MIEKFYEIELWKDPKAPP-RGVLLEKVR-EVDALVTLVTDKV 57

Query: 75  GETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAA 134
            + L     K   K  +  AVGY+N+D+E A K GI V NTPGVLT+ TA+LA +L LA 
Sbjct: 58  DKELLENAPKL--KIIAQYAVGYDNIDIEEATKRGIYVTNTPGVLTDATADLAFALLLAV 115

Query: 135 ARRIVEADEFMRGGLYE----GWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKM 190
           ARRIVEAD F+R G ++    GW P +F+G  LKG+T+G++G GRIG A A+   +GF M
Sbjct: 116 ARRIVEADAFVRSGEWKKSEVGWHPLMFLGYGLKGKTLGIVGFGRIGQALAKR-AKGFGM 174

Query: 191 NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTT 250
            +IY+   +    E+ + A                     E +L+E+D ISLH  L K T
Sbjct: 175 KIIYYSRTRKPEAEEEIGA----------------EYVDFETLLKESDFISLHVPLTKET 218

Query: 251 YHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLA 310
           YH++ ++ L +MK  AIL+N SRG V+D  AL++ LKE  +   GLDVFEEEP+    L 
Sbjct: 219 YHMIGEKELKLMKPNAILINTSRGAVVDTNALIKALKEGWIAGAGLDVFEEEPYYNEELF 278

Query: 311 DTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASP 366
             KN ++ PHI SA+   REGMA L A N++   KG      PN V+  +  ++ P
Sbjct: 279 KLKNVVLAPHIGSATHEAREGMAELVAKNLIAFAKGEI---PPNLVNKDVLTSSPP 331
>ref|ZP_01741677.1| glycerate dehydrogenase [Rhodobacterales bacterium HTCC2150]
 gb|EBA04130.1| glycerate dehydrogenase [Rhodobacterales bacterium HTCC2150]
          Length = 371

 Score =  459 bits (1183), Expect = e-127,   Method: Composition-based stats.
 Identities = 100/351 (28%), Positives = 178/351 (50%), Gaps = 23/351 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P+ +  VV T+ +P    I   + +   V +       ++ ++++  +    D ++  +T
Sbjct: 44  PHKQLSVVVTRRLPEP--IERRLAELFDVNL-RESDAPMTRDELVSAMKT-ADILVPTIT 99

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     + +       K  +N   G ++++V+AA   G+ V NTPGVLTE TA++  +L 
Sbjct: 100 DTIDAEMLAQAGD-QLKLLANYGAGIDHINVDAARARGVLVSNTPGVLTEDTADMTMALI 158

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           LA  RRI +    M+ G +EGW P   +G  + G+ +G++G GRIG A AR     F MN
Sbjct: 159 LAVTRRIPDGLALMQTGQWEGWSPTALMGGRIAGRNLGILGMGRIGQAVARR-ASAFGMN 217

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y + ++              L+   E  +      S+++++   D++S++      T+
Sbjct: 218 VHYHNRHR--------------LRTETEAALNATYWDSLDQMVARTDVLSVNCPHTPATF 263

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N  RL +MK+ A++VN SRG VIDE AL   L+   +   GLDV+E+   + P L +
Sbjct: 264 HLMNARRLKLMKETAVIVNTSRGEVIDENALTRMLRSGEISGAGLDVYEKGREVNPRLRE 323

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNE 362
            KN +++PH+ SA+   R  M     +N+     G+     P+ V P +++
Sbjct: 324 LKNVVLLPHMGSATVEARMEMGEKVLINIKTFDDGH---RPPDLVLPGMDD 371
>ref|YP_077041.1| putative glycerate dehydrogenase [Symbiobacterium thermophilum IAM
           14863]
 dbj|BAD42197.1| putative glycerate dehydrogenase [Symbiobacterium thermophilum IAM
           14863]
          Length = 332

 Score =  459 bits (1183), Expect = e-127,   Method: Composition-based stats.
 Identities = 122/352 (34%), Positives = 176/352 (50%), Gaps = 26/352 (7%)

Query: 14  GKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTED 73
            K RV  T+ +P      L     C V     +   +  ++++  +  + DG +      
Sbjct: 2   AKPRVFVTRRIPDEALSILRTA--CEVHTWDHEDEPVPQDELVRGLQ-EADGALVVGPHR 58

Query: 74  WGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLA 133
               L  A      + ++NMAVGY+N+DV AA   GI + NTPGVLTETTA+LA  L +A
Sbjct: 59  IDAALMDAAP--RCRVYANMAVGYDNIDVAAATARGILITNTPGVLTETTADLAFGLMIA 116

Query: 134 AARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLI 193
           AARR+ E    +  G ++GW P    G  + G T+G++GAGRIG A AR    GF M ++
Sbjct: 117 AARRLYEGQRTIVEGRWKGWSPMFMTGQDVYGATLGIVGAGRIGQAVARR-ARGFDMRIL 175

Query: 194 YFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHL 253
           Y +   +   E  V A                    ++++LRE+D + +   L   T  L
Sbjct: 176 YHNRRPNPAFEAEVGAS----------------YRLLDDLLRESDFVVVLVPLTPETRGL 219

Query: 254 VNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFM-KPGLADT 312
           +    LA+MK  A+LVN +RGPV+DE AL E L++  ++  GLDVF+ EP      L   
Sbjct: 220 IGARELALMKPTAVLVNAARGPVVDERALYEALRDRRIYAAGLDVFDREPIPADHPLLSL 279

Query: 313 KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENA 364
            N   VPHI SA+  TR  MATLAA N++  + G      P  V+P +    
Sbjct: 280 PNVTAVPHIGSATVRTRTRMATLAAENLVAALTGK---QPPTPVNPEVLRRE 328
>ref|ZP_01444314.1| 2-hydroxyacid dehydrogenase [Roseovarius sp. HTCC2601]
 gb|EAU45472.1| 2-hydroxyacid dehydrogenase [Roseovarius sp. HTCC2601]
          Length = 328

 Score =  459 bits (1182), Expect = e-127,   Method: Composition-based stats.
 Identities = 106/350 (30%), Positives = 176/350 (50%), Gaps = 23/350 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P  +  VV T+ +P    +   + +   V +     T +S  ++ + +  +CD ++  +T
Sbjct: 2   PQKRLSVVVTRRLPEA--VETRLSELFNVTL-RESDTPMSRAELAEAMA-ECDVLVPTIT 57

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     L     +   K  +N   G +++DVE A + GI V NTPGV+T+ TA++   L 
Sbjct: 58  DPIDAGLIGQAGE-RLKLIANYGAGVDHIDVETARRRGILVSNTPGVMTDDTADMVMGLM 116

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           LA  RR+ E    M+ G +EGW P+ F+G  L G+ +G++G GRIG A A+   + F M 
Sbjct: 117 LAVTRRMQEGLAVMQAGTWEGWAPNAFLGTRLGGKRLGILGMGRIGQAVAKR-AQAFGMQ 175

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +  +              L+   E         S+++++   D+IS++     +T+
Sbjct: 176 IHYHNRRR--------------LRPETEDAFEATYWESLDQMVARMDVISVNCPHTPSTF 221

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N  RL +MK  A+LVN SRG VIDE+AL   LK   +   GLDV++      P L +
Sbjct: 222 HLLNARRLKLMKPSAVLVNTSRGEVIDESALTRMLKAGELAGAGLDVYQHGIKGNPELVN 281

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
             N +++PH+ SA+   R  M     LNV     G+     P++V P ++
Sbjct: 282 MPNVVMLPHMGSATIEGRIEMGEKVLLNVKTFADGH---RPPDQVVPAMH 328
>ref|ZP_03856830.1| lactate dehydrogenase-like oxidoreductase [Thermobaculum terrenum
           ATCC BAA-798]
 gb|EEI02352.1| lactate dehydrogenase-like oxidoreductase [Thermobaculum terrenum
           ATCC BAA-798]
          Length = 319

 Score =  457 bits (1178), Expect = e-127,   Method: Composition-based stats.
 Identities = 133/343 (38%), Positives = 191/343 (55%), Gaps = 30/343 (8%)

Query: 16  YRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWG 75
           YRV  T+ +P    + LL D G  ++I        S E++   I  + D +I  LT+   
Sbjct: 2   YRVYITRKIP-EAGLRLLKDHGFELDIW-PGDLPPSKEELKRGIS-QADAMISLLTDKID 58

Query: 76  ETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAA 135
           E + S       K  +N AVGY+N+D+EAA K GI V NTP VLTETTA+LA +L L+ A
Sbjct: 59  EEVISNARNL--KVIANYAVGYDNIDLEAATKAGIVVTNTPDVLTETTADLAWALMLSVA 116

Query: 136 RRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYF 195
           RR++E    ++ G +  W P L +G  + G T+G++G GRIG A AR    GF+M ++Y 
Sbjct: 117 RRLIEGVSHVKDGKWRTWEPQLLLGQDVYGATLGIVGMGRIGQAVARR-AIGFQMKVLYT 175

Query: 196 DLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVN 255
              + T ++                     +  S++E+L ++D ISLH  L K T H++N
Sbjct: 176 SRSEKTGID--------------------AQKVSLDELLAQSDFISLHTPLTKETRHMIN 215

Query: 256 KERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFM-KPGLADTKN 314
           K  L  MK  AIL+N +RGP++D AALVE L+E  +   GLDV + EP      L    N
Sbjct: 216 KSTLKRMKPTAILINTARGPLVDTAALVEALREGQIAGAGLDVTDPEPLPRNHPLLYLPN 275

Query: 315 AIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVD 357
            IVVPHI SAS+ TR+ M+ +AA NV+  ++G      PN+V+
Sbjct: 276 CIVVPHIGSASQRTRDLMSEIAARNVIAVLEG---SQAPNQVN 315
>ref|YP_612475.1| Glycolate reductase [Silicibacter sp. TM1040]
 gb|ABF63213.1| Glycolate reductase [Silicibacter sp. TM1040]
          Length = 328

 Score =  457 bits (1178), Expect = e-127,   Method: Composition-based stats.
 Identities = 102/350 (29%), Positives = 173/350 (49%), Gaps = 23/350 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P  +  VV T+ +P    +   + +   V +     T ++  ++   +  + D ++  +T
Sbjct: 2   PRERLSVVVTRRLPEP--VETRLSELFDVRL-RTDDTPMTRTELAAAMK-EADVLVPTVT 57

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     L     +   +  +N   G +N+DV  A + GI V NTPGVLT+ TA++  +L 
Sbjct: 58  DTIDAGLLGQAGE-RLRLIANYGAGVDNIDVATARQRGILVSNTPGVLTDDTADMTMALI 116

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           +A  RRI E    M+ G +EGW P   +G  L G+ +G++G GRIG A AR     F M 
Sbjct: 117 MAVVRRIPEGLAIMQRGDWEGWSPTAMLGGRLAGRRLGILGMGRIGQAVARR-ARAFGMQ 175

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +  +              L+   E+ +      S+++++   D+IS+H     +T+
Sbjct: 176 VHYNNRRR--------------LRPEVEEELEATWWESLDQMVARMDVISIHCPSTPSTF 221

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N  RL ++K +A++VN SRG VIDE AL   L+   +   GLDV+E    + P L +
Sbjct: 222 HLMNARRLKLLKPDAVIVNTSRGEVIDENALTRGLRAGEIAGCGLDVYEHGTTVNPRLRE 281

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
             N +++PH+ SA+   R  M     LN+     G+     P++V P + 
Sbjct: 282 LPNVVLLPHMGSATIEGRIEMGEKVLLNIKTFEDGH---RPPDQVVPAML 328
>ref|ZP_02164852.1| 2-hydroxyacid dehydrogenase [Hoeflea phototrophica DFL-43]
 gb|EDQ35547.1| 2-hydroxyacid dehydrogenase [Hoeflea phototrophica DFL-43]
          Length = 334

 Score =  457 bits (1177), Expect = e-127,   Method: Composition-based stats.
 Identities = 96/351 (27%), Positives = 168/351 (47%), Gaps = 28/351 (7%)

Query: 13  NGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTE 72
             K +V  T+ +P      +       + I    +      +++  +    D ++  +T+
Sbjct: 4   RKKPKVYITRRLPDQVETRMRELFDAELNITDEPRAQP---ELVAAMRS-ADVLVPTVTD 59

Query: 73  DWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSL 132
                L         K  +N   G +N+DV+AA K GI V NTP VL++ TA++  +L L
Sbjct: 60  KIDAALIEQA-GPQMKLIANFGNGVDNIDVDAAQKKGITVTNTPNVLSDDTADMTMALML 118

Query: 133 AAARRIVEADEFM--RGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKM 190
           A  RR+ E    +    G ++GW P   +G+ + G+ +G+IG GRIG+A AR   + F +
Sbjct: 119 AVPRRLTEGANVLVGNDGSWKGWSPTWMLGHRIGGKRLGIIGMGRIGTAVARR-AKAFGL 177

Query: 191 NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTT 250
           ++ Y +  +              +  + E  +      S++++L   D++S++      T
Sbjct: 178 SIHYHNRRR--------------VDPDTEDQLEATYWDSLDQMLARVDIVSVNCPSTPAT 223

Query: 251 YHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLA 310
           +HL++  RL +MK  A +VN +RG +IDE AL++ L+E  +   GLDVFE EP +   L 
Sbjct: 224 FHLLSARRLELMKPGAYIVNTARGGIIDEDALIKALREGRLSGAGLDVFEHEPAVDKRLV 283

Query: 311 DT---KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDP 358
                   +++PH+ SA+   R  M     +N+     G+     P+RV P
Sbjct: 284 KLASEGRVVLLPHMGSATMEGRIDMGDKVIINIRTFFDGH---RPPDRVLP 331
>ref|YP_765750.1| putative glyoxylate reductase [Rhizobium leguminosarum bv. viciae
           3841]
 emb|CAK05634.1| putative glyoxylate reductase [Rhizobium leguminosarum bv. viciae
           3841]
          Length = 333

 Score =  457 bits (1177), Expect = e-127,   Method: Composition-based stats.
 Identities = 102/356 (28%), Positives = 174/356 (48%), Gaps = 28/356 (7%)

Query: 10  YNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQ 69
                K +V  T+ +P      +       + I        SV ++I  +    D ++  
Sbjct: 1   MTAKKKPKVYITRKLPDAVETRMRELFDAELNI---DDAPRSVPELIAAVKT-ADVLVPT 56

Query: 70  LTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAAS 129
           +T+     L         K  ++ + G +++DVEAA + GI V NTP VLTE TA++  +
Sbjct: 57  VTDRIDAALIEQA-GPQMKLIASFSNGTDHIDVEAAARKGITVTNTPNVLTEDTADMTMA 115

Query: 130 LSLAAARRIVEADEFM--RGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEG 187
           L LA  RR+ E    +  + G + GW P   +G  + G+ +G++G GRIG+A AR   + 
Sbjct: 116 LILAVPRRLGEGARVLTDKPGEWAGWSPTWMLGRRIHGKRIGIVGMGRIGTAVARR-AKA 174

Query: 188 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLD 247
           F +++ Y +  +              +    E  +      S++++L   D++S++    
Sbjct: 175 FGLSIHYHNRKR--------------VNPAVEDELEATYWESLDQMLARVDIVSVNCPST 220

Query: 248 KTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKP 307
             T+HL++  RLA+++  A LVN +RG V+DEAAL++ L+E  +   GLDVFE EP + P
Sbjct: 221 PATFHLISARRLALLQPTAYLVNTARGDVVDEAALIKCLREGRIAGAGLDVFENEPAVNP 280

Query: 308 GLADTKN---AIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
            L    N    +++PH++SA+   R  M     +N+   + G+     PNRV P  
Sbjct: 281 RLIKLANEGKVVLLPHMSSATIEGRIDMGDKVIINIRTFIDGH---RPPNRVLPGR 333
>ref|YP_001414898.1| Glyoxylate reductase [Parvibaculum lavamentivorans DS-1]
 gb|ABS65241.1| Glyoxylate reductase [Parvibaculum lavamentivorans DS-1]
          Length = 330

 Score =  456 bits (1175), Expect = e-126,   Method: Composition-based stats.
 Identities = 105/351 (29%), Positives = 174/351 (49%), Gaps = 25/351 (7%)

Query: 13  NGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTE 72
             K  V+ T+ +P    I   + +   V + +      S  ++   I  + D ++  +T+
Sbjct: 3   AKKPLVIVTRKLPAP--IEARMGELFDVRL-NGDDHPFSAAELAAAIR-EADVLVPTVTD 58

Query: 73  DWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSL 132
                L S   +   +  +    G +N+DVE A + GI V NTPGVLTE TA++   L L
Sbjct: 59  RIDARLLSQAGE-NLRLIAQFGTGVDNIDVETARRRGITVTNTPGVLTEDTADMTMGLLL 117

Query: 133 AAARRIVEADEFMRG--GLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKM 190
           A  RR+ E   ++R   G + GW P   +G  L G+ +G+IG GRIG A AR   + F +
Sbjct: 118 AVPRRLAEGSRYLREHEGQWPGWSPTWMLGRRLTGKRLGIIGMGRIGQAVARR-AKPFGL 176

Query: 191 NLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTT 250
            + Y +   +               A  EQ +  +   +++++L + D++S++  L   T
Sbjct: 177 EIHYHNRKPA--------------NAVIEQELEARFWENLDDMLPKVDIVSVNCPLTPQT 222

Query: 251 YHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLA 310
           +HL++  RL ++K EA +VN +RG +IDE AL+  L+   +   GLDVFE EP + P L 
Sbjct: 223 FHLLDTRRLKLLKPEAYIVNTARGEIIDENALIRALEAGELAGAGLDVFEHEPTVNPRLL 282

Query: 311 DTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
              N + +PH+ SA+   R  M     +N+   + G+     P+RV P + 
Sbjct: 283 KLPNVVSLPHMGSATIEGRVEMGGKVIVNIKTFMDGH---RPPDRVIPAIM 330
>ref|ZP_02294079.1| Glyoxylate reductase [Rhizobium leguminosarum bv. trifolii WSM1325]
 gb|EDR77564.1| Glyoxylate reductase [Rhizobium leguminosarum bv. trifolii WSM1325]
          Length = 333

 Score =  456 bits (1175), Expect = e-126,   Method: Composition-based stats.
 Identities = 102/356 (28%), Positives = 174/356 (48%), Gaps = 28/356 (7%)

Query: 10  YNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQ 69
                K +V  T+ +P      +       + I        SV ++I  +    D ++  
Sbjct: 1   MTAKKKPKVYITRKLPDAVETRMRELFDAELNI---DDAPRSVAELIAAVKT-ADVLVPT 56

Query: 70  LTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAAS 129
           +T+     L         K  ++ + G +++DVEAA + GI V NTP VLTE TA++  +
Sbjct: 57  VTDRIDAALIEEA-GPQMKLIASFSNGTDHIDVEAAARKGITVTNTPNVLTEDTADMTMA 115

Query: 130 LSLAAARRIVEADEFM--RGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEG 187
           L LA  RR+ E    +  + G + GW P   +G  + G+ +G++G GRIG+A AR   + 
Sbjct: 116 LILAVPRRLGEGARVLTDKPGEWAGWSPTWMLGRRIHGKRIGIVGMGRIGTAVARR-AKA 174

Query: 188 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLD 247
           F +++ Y +  +              +    E  +      S++++L   D++S++    
Sbjct: 175 FGLSIHYHNRKR--------------VNPAVEDELEATYWESLDQMLARVDIVSINCPST 220

Query: 248 KTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKP 307
             T+HL++  RLA+++  A LVN +RG V+DEAAL++ L+E  +   GLDVFE EP + P
Sbjct: 221 PATFHLISARRLALLQPTAYLVNTARGDVVDEAALIKCLREGRIAGAGLDVFENEPAVNP 280

Query: 308 GLADTKN---AIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
            L    N    +++PH++SA+   R  M     +N+   + G+     PNRV P  
Sbjct: 281 RLIKLANEGKVVLLPHMSSATIEGRIDMGDKVIINIRTFIDGH---RPPNRVLPGR 333
>ref|ZP_02144459.1| hypothetical protein RGBS107_02823 [Phaeobacter gallaeciensis
           BS107]
 gb|EDQ13996.1| hypothetical protein RGBS107_02823 [Phaeobacter gallaeciensis
           BS107]
          Length = 328

 Score =  456 bits (1174), Expect = e-126,   Method: Composition-based stats.
 Identities = 101/350 (28%), Positives = 173/350 (49%), Gaps = 23/350 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
              +  VV T+ +P    +   + +   V +     T +S  ++   + D  D ++  +T
Sbjct: 2   ARERLSVVVTRRLPEP--VETRLSELFDVRL-REDDTPMSRAELATALKD-ADVLVPTVT 57

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           ++    L         K  +N   G +++DV  A + GI V NTPGVLT+ TA++A +L 
Sbjct: 58  DEIDAGLLGQAGD-RLKLIANYGAGVDHIDVATARQRGILVSNTPGVLTDDTADMAMALI 116

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           +A  RRI E    M+ G ++GW P   +G  L G+ +G++G G IG A A+     F M 
Sbjct: 117 MAVVRRIPEGLAVMQKGDWQGWSPTALLGGRLAGRRLGILGMGSIGQAVAKRAA-AFGMQ 175

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +  +              L+   EQ        S+++++   D++S++     +T+
Sbjct: 176 VHYHNRRR--------------LRPEIEQRFEATYWESLDQMVARMDVLSINCPSTPSTF 221

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N  RL +MK +A++VN SRG VIDE AL   L+ + +   GLDV+E    + P L +
Sbjct: 222 HLMNARRLKLMKPDAVIVNTSRGEVIDEHALTRMLRASEIAGAGLDVYEHGTDINPRLRE 281

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
            +N +++PH+ SA+   R  M     LN+     G+     P++V P + 
Sbjct: 282 LENVVLLPHMGSATLEGRLEMGEKVLLNIKTFEDGH---RPPDQVVPSML 328
>ref|ZP_02190699.1| Lactate dehydrogenase and related dehydrogenase [alpha
           proteobacterium BAL199]
 gb|EDP62542.1| Lactate dehydrogenase and related dehydrogenase [alpha
           proteobacterium BAL199]
          Length = 328

 Score =  456 bits (1174), Expect = e-126,   Method: Composition-based stats.
 Identities = 95/350 (27%), Positives = 176/350 (50%), Gaps = 23/350 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P  K  V+ T+ +P      ++     R+   +L    ++ +++   +  + D ++  +T
Sbjct: 2   PQTKPLVIVTRKLPDAVETRMMELFRTRL---NLSDQPMTRDELAAAMR-EADVLVPTVT 57

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     L     +   K  ++   G +++D+ AA    I + NTPGVLTE TA++  +L 
Sbjct: 58  DRIDAGLIEQAGE-RLKLIASFGTGVDHIDLRAAKARHITITNTPGVLTEDTADMTMALI 116

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           LA  RRIVE +  ++ G + GW P   +G+ + G+ +G++G GRIGSA AR    GF ++
Sbjct: 117 LAVPRRIVEGNALIQTGTWNGWSPTGMLGHRIHGKRLGIVGMGRIGSAVARR-ARGFGLS 175

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y + ++              +  + E  +      ++++++   D++S++      T+
Sbjct: 176 VHYHNRHR--------------VHPDLEAELEATYWDNLDQMMGRMDIVSVNCPHTPATF 221

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N+ R+ +M+  A +VN +RG VIDEAAL E L E  +   GLDV+E EP +   +  
Sbjct: 222 HLINRRRIGLMQPHAYIVNTARGEVIDEAALTEALDEKRIAGAGLDVYEHEPKVNSDMLS 281

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
             N +++PH+ SA+   R  M     +N+      +     P+RV   + 
Sbjct: 282 LDNVVLLPHMGSATIEGRRDMGERVIVNIRTFADAH---TPPDRVVETMF 328
>ref|ZP_02855508.1| Glyoxylate reductase [Rhizobium leguminosarum bv. trifolii WSM2304]
 gb|EDS69607.1| Glyoxylate reductase [Rhizobium leguminosarum bv. trifolii WSM2304]
          Length = 333

 Score =  455 bits (1173), Expect = e-126,   Method: Composition-based stats.
 Identities = 102/356 (28%), Positives = 174/356 (48%), Gaps = 28/356 (7%)

Query: 10  YNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQ 69
                K +V  T+ +P      +       + I        SV ++I  +    D ++  
Sbjct: 1   MTAKKKPKVYITRKLPDAVETRMRELFDAELNI---DDAPRSVPELIAAVRT-ADVLVPT 56

Query: 70  LTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAAS 129
           +T+     L         K  ++ + G +++DVEAA + GI V NTP VLTE TA++  +
Sbjct: 57  VTDRIDAALIDEA-GPQMKLIASFSNGTDHIDVEAAARKGITVTNTPNVLTEDTADMTMA 115

Query: 130 LSLAAARRIVEADEFM--RGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEG 187
           L LA  RR+ E    +  + G + GW P   +G  + G+ +G++G GRIG+A AR   + 
Sbjct: 116 LILAVPRRLGEGARVLTDKPGEWAGWSPTWMLGRRIHGKRIGIVGMGRIGTAVARR-AKA 174

Query: 188 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLD 247
           F +++ Y +  +              +    E  +      S++++L   D++S++    
Sbjct: 175 FGLSIHYHNRKR--------------VNPAVEDELEATYWESLDQMLARVDIVSVNCPST 220

Query: 248 KTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKP 307
             T+HL++  RLA+++  A LVN +RG V+DEAAL++ L+E  +   GLDVFE EP + P
Sbjct: 221 PATFHLISARRLALLQPTAYLVNTARGDVVDEAALIKALREGRIAGAGLDVFENEPAVNP 280

Query: 308 GLADTKN---AIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
            L    N    +++PH++SA+   R  M     +N+   + G+     PNRV P  
Sbjct: 281 KLVKLANEGKVVLLPHMSSATIEGRIDMGDKVIINIRTFIDGH---RPPNRVLPGR 333
>ref|YP_508857.1| Glycolate reductase [Jannaschia sp. CCS1]
 gb|ABD53832.1| Glycolate reductase [Jannaschia sp. CCS1]
          Length = 328

 Score =  455 bits (1171), Expect = e-126,   Method: Composition-based stats.
 Identities = 100/350 (28%), Positives = 176/350 (50%), Gaps = 23/350 (6%)

Query: 12  PNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLT 71
           P+ +  VV T+ +P    +   + +   VE+       ++ ++++D +  + D ++  +T
Sbjct: 2   PSQRLSVVVTRRLPEA--VETRMSELFDVEL-REDDRPMTRDELVDAMK-RTDVLVPCIT 57

Query: 72  EDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLS 131
           +     +         K  +N   G ++VDV  A + G+ V NTPGV+T+ TA++  +L 
Sbjct: 58  DVIDGGMLGQAGD-RLKLIANYGAGVDHVDVSTARQRGVLVSNTPGVMTDDTADMVMALI 116

Query: 132 LAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMN 191
           L   RR+ E    M+ G + GW P  F+G  + G+ +G++G GRIG A AR     F M 
Sbjct: 117 LGVLRRVPEGMAEMQEGNWAGWAPTAFMGGRVGGKRLGILGMGRIGQAVARRAA-AFGMQ 175

Query: 192 LIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTY 251
           + Y +  +              L  + E  +      S+++++   D++S++     +T+
Sbjct: 176 VHYHNRRR--------------LHEDVEGALEATYWDSLDQMIARMDVVSVNCPHTPSTF 221

Query: 252 HLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLAD 311
           HL+N  RL +MK EA++VN SRG VIDE AL   L+   +   GLDVFE+   + P L +
Sbjct: 222 HLMNARRLKLMKPEAVIVNTSRGEVIDENALTRMLRSGEIAGAGLDVFEKGREVNPRLRE 281

Query: 312 TKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
             NA+++PH+ SA++  R  M     +N+     G+     P+ V P + 
Sbjct: 282 LSNAVLLPHMGSATREGRAEMGEKVLINIKTFADGH---RPPDLVVPSML 328
>ref|YP_467690.1| probable D-2-hydroxyacid dehydrogenase protein [Rhizobium etli CFN
           42]
 gb|ABC88963.1| probable D-2-hydroxyacid dehydrogenase protein [Rhizobium etli CFN
           42]
          Length = 333

 Score =  455 bits (1171), Expect = e-126,   Method: Composition-based stats.
 Identities = 101/356 (28%), Positives = 173/356 (48%), Gaps = 28/356 (7%)

Query: 10  YNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQ 69
                K +V  T+ +P      +       + I        SV ++I  +    D ++  
Sbjct: 1   MTAKKKPKVYITRKLPDAVETRMRELFDAELNI---DDAPRSVPELIAAVRT-ADVLVPT 56

Query: 70  LTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAAS 129
           +T+     L         K  ++ + G +++DVEAA + GI V NTP VLTE TA++  +
Sbjct: 57  VTDRIDAALIDEA-GPQMKLIASFSNGTDHIDVEAAARKGITVTNTPNVLTEDTADMTMA 115

Query: 130 LSLAAARRIVEADEFM--RGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEG 187
           L LA  RR+ E    +  + G + GW P   +G  + G+ +G++G GRIG+A AR   + 
Sbjct: 116 LILAVPRRLGEGARILTDKPGEWAGWSPTWMLGRRIHGKRIGIVGMGRIGTAVARR-AKA 174

Query: 188 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLD 247
           F +++ Y +  +              +    E  +      S++++L   D++S++    
Sbjct: 175 FGLSIHYHNRKR--------------VNPAVEDELEATYWESLDQMLARVDIVSINCPST 220

Query: 248 KTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKP 307
             T+HL++  RLA+++  A LVN +RG V+DE AL++ L+E  +   GLDVFE EP + P
Sbjct: 221 PATFHLISARRLALLQPTAYLVNTARGDVVDETALIKCLREGRIAGAGLDVFENEPAVNP 280

Query: 308 GLADTKN---AIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFL 360
            L    N    +++PH++SA+   R  M     +N+   + G+     PNRV P  
Sbjct: 281 KLVKLANEGKVVLLPHMSSATIEGRIDMGDKVIINIRTFIDGH---RPPNRVLPGR 333
>ref|YP_676475.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Mesorhizobium sp. BNC1]
 gb|ABG65310.1| D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
           [Mesorhizobium sp. BNC1]
          Length = 333

 Score =  454 bits (1170), Expect = e-126,   Method: Composition-based stats.
 Identities = 97/353 (27%), Positives = 169/353 (47%), Gaps = 27/353 (7%)

Query: 10  YNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQ 69
                K  VV T+ +P      +      R+ I       ++  +++  +  + D ++  
Sbjct: 1   MTGRKKPLVVITRKLPDQVETRMRELFDARLNI---DDGPMTQPELVAAVK-EADVLVPT 56

Query: 70  LTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAAS 129
           +T+     L +   +   K  +N   G  ++DV AA + GI V NTP VL E TA++  +
Sbjct: 57  ITDRIDAALLAQAGE-RLKLIANYGNGVEHIDVTAAAERGITVTNTPNVLNEDTADMTMA 115

Query: 130 LSLAAARRIVEADEFMRGG-LYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGF 188
           L LA  RR+VE  E ++ G  + GW P   +G  + G+ +G++G GRIG+A AR   + F
Sbjct: 116 LMLAVPRRLVEGAEMLKQGGKWAGWSPTWMLGRRIWGKRLGIVGMGRIGTAVARR-AKAF 174

Query: 189 KMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDK 248
            +++ Y +  +              +    E  +      S++++L   D+IS++     
Sbjct: 175 GLSIHYHNRRR--------------VAPMIEDELEATYWDSLDQMLARMDIISVNCPSTP 220

Query: 249 TTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPG 308
            TYHL++  RLA+M+  + LVN +RG ++DE AL+  ++E  +   GLDVF  EP +   
Sbjct: 221 ATYHLLSARRLALMQPSSYLVNTARGEIVDEEALIRMIEEGKLAGAGLDVFAHEPAVSRR 280

Query: 309 LADTK---NAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDP 358
           L         +++PH+ SA+   R  M     +N+     G+     P+RV P
Sbjct: 281 LLKLSEIGKVVILPHMGSATIEGRIDMGEKVIINIRAFFDGH---RPPDRVLP 330
>ref|NP_384280.1| 2-hydroxyacid dehydrogenase [Sinorhizobium meliloti 1021]
 emb|CAC41561.1| Probable glyoxylate reductase [Sinorhizobium meliloti 1021]
          Length = 334

 Score =  454 bits (1169), Expect = e-126,   Method: Composition-based stats.
 Identities = 101/357 (28%), Positives = 177/357 (49%), Gaps = 28/357 (7%)

Query: 10  YNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQ 69
                K  V  T+ +P      +       + I     T  S  +++  +  + D ++  
Sbjct: 1   MTSKKKPTVYITRKLPDVVETRMRELFDAELNI---DDTPRSQPELVAAVK-RADVLVPT 56

Query: 70  LTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAAS 129
           +T+     L         K  +  + G +N+DV+AA + GI V NTP VLTE TA++  +
Sbjct: 57  VTDRIDAALIEQA-GPQLKLIAAFSNGVDNIDVDAAARKGITVTNTPNVLTEDTADMTMA 115

Query: 130 LSLAAARRIVEADEFM--RGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEG 187
           L LA  RR+ E  + +  R G + GW P   +G  + G+ +G++G GRIG+A AR   + 
Sbjct: 116 LILAVPRRLAEGAQVLTDRKGEWAGWSPTWMLGRRIAGKRIGIVGMGRIGTAVARR-AKA 174

Query: 188 FKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLD 247
           F +++ Y + ++              +K   E+ +      S++++L   D++S++    
Sbjct: 175 FGLSIHYHNRHR--------------VKPETEEMLEATYWDSLDQMLARVDIVSVNCPST 220

Query: 248 KTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKP 307
             TYHL++  RLA+M+ ++ +VN +RG +IDEAAL++ L+E  +   GLDVFE EP + P
Sbjct: 221 PATYHLLSARRLALMRPDSYIVNTARGGIIDEAALIKSLREGKIAGAGLDVFENEPCVNP 280

Query: 308 GLADT---KNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLN 361
            L         +++PH++SA+   R  M     +N+     G+     P+RV P  +
Sbjct: 281 KLIKLAGEGKVVLLPHMSSATLEGRIDMGEKVVINIRTFFDGH---RPPDRVLPGRD 334
  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF excluding environmental samples
  from WGS projects
    Posted date:  May 23, 2008  5:56 PM
  Number of letters in database: 883,778,997
  Number of sequences in database:  2,617,685
  
  Database: /host/Blast/data/nr_perl/nr.01
    Posted date:  May 23, 2008  5:54 PM
  Number of letters in database: 976,759,346
  Number of sequences in database:  2,761,413
  
  Database: /host/Blast/data/nr_perl/nr.02
    Posted date:  May 23, 2008  5:48 PM
  Number of letters in database: 374,670,760
  Number of sequences in database:  1,165,270
  
  Database: /host/Blast/data/nr_perl/nr.03
    Posted date:  Apr 28, 2009  5:40 PM
  Number of letters in database: 114,943,120
  Number of sequences in database:  354,819
  
Lambda     K      H
   0.314    0.185    0.606 

Lambda     K      H
   0.267   0.0566    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,070,572,237
Number of Sequences: 6899187
Number of extensions: 557171803
Number of successful extensions: 1271422
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 14392
Number of HSP's successfully gapped in prelim test: 2736
Number of HSP's that attempted gapping in prelim test: 1210754
Number of HSP's gapped (non-prelim): 18801
length of query: 386
length of database: 2,350,152,223
effective HSP length: 136
effective length of query: 250
effective length of database: 1,411,862,791
effective search space: 352965697750
effective search space used: 352965697750
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 81 (35.3 bits)