BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= CAA33547.1__[Trypanosoma_brucei]
         (607 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           6,899,187 sequences; 2,350,152,223 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P13377|G6PI_TRYBB  Glucose-6-phosphate isomerase, glycoso...  1258   0.0  
pdb|2O2C|A  Chain A, Crystal Structure Of Phosphoglucose Iso...  1252   0.0  
ref|XP_001219077.1|  glucose-6-phosphate isomerase, glycosom...  1251   0.0  
ref|XP_820895.1|  glucose-6-phosphate isomerase, glycosomal,...   961   0.0  
ref|XP_821969.1|  glucose-6-phosphate isomerase, glycosomal,...   959   0.0  
emb|CAF05827.1|  glucose-6-phosphate isomerase [Leishmania d...   899   0.0  
emb|CAF05824.1|  glucose-6-phosphate isomerase [Leishmania d...   898   0.0  
ref|XP_001463984.1|  glucose-6-phosphate isomerase [Leishman...   898   0.0  
emb|CAF05839.1|  glucose-6-phosphate isomerase [Leishmania d...   895   0.0  
emb|CAF05831.1|  glucose-6-phosphate isomerase [Leishmania i...   895   0.0  
emb|CAF05819.1|  glucose-6-phosphate isomerase [Leishmania i...   895   0.0  
ref|XP_001681659.1|  glucose-6-phosphate isomerase [Leishman...   890   0.0  
sp|P42861|G6PI_LEIME  Glucose-6-phosphate isomerase (GPI) (P...   887   0.0  
gb|ABU25165.1|  glucose-6-phosphate isomerase [Leishmania br...   875   0.0  
ref|XP_001563099.1|  glucose-6-phosphate isomerase [Leishman...   874   0.0  
gb|ABU25168.1|  glucose-6-phosphate isomerase [Leishmania la...   874   0.0  
gb|ABU25166.1|  glucose-6-phosphate isomerase [Leishmania gu...   873   0.0  
pdb|1Q50|A  Chain A, Phosphoglucose Isomerase From Leishmani...   860   0.0  
gb|AAR89408.1|  glucose-6-phosphate isomerase [Trypanosoma b...   854   0.0  
gb|AAR89410.1|  glucose-6-phosphate isomerase [Trypanosoma b...   847   0.0  
gb|AAR89411.1|  glucose-6-phosphate isomerase [Trypanosoma b...   846   0.0  
gb|AAR89409.1|  glucose-6-phosphate isomerase [Trypanosoma b...   846   0.0  
gb|AAR89412.1|  glucose-6-phosphate isomerase [Trypanosoma c...   793   0.0  
gb|AAR89396.1|  glucose-6-phosphate isomerase [Trypanosoma c...   706   0.0  
gb|AAR89394.1|  glucose-6-phosphate isomerase [Trypanosoma c...   704   0.0  
gb|AAR89398.1|  glucose-6-phosphate isomerase [Trypanosoma c...   704   0.0  
gb|AAR89407.1|  glucose-6-phosphate isomerase [Trypanosoma r...   704   0.0  
gb|AAR89403.1|  glucose-6-phosphate isomerase [Trypanosoma c...   702   0.0  
gb|AAR89397.1|  glucose-6-phosphate isomerase [Trypanosoma c...   701   0.0  
emb|CAH90643.1|  glucose-6-phosphate isomerase [Leishmania s...   700   0.0  
gb|AAR89406.1|  glucose-6-phosphate isomerase [Trypanosoma c...   700   0.0  
gb|AAR89399.1|  glucose-6-phosphate isomerase [Trypanosoma c...   699   0.0  
gb|AAR89405.1|  glucose-6-phosphate isomerase [Trypanosoma c...   697   0.0  
gb|AAR89402.1|  glucose-6-phosphate isomerase [Trypanosoma c...   695   0.0  
gb|AAR89401.1|  glucose-6-phosphate isomerase [Trypanosoma c...   695   0.0  
gb|AAR89400.1|  glucose-6-phosphate isomerase [Trypanosoma c...   694   0.0  
gb|AAR89404.1|  glucose-6-phosphate isomerase [Trypanosoma c...   694   0.0  
emb|CAH90641.2|  glucose-6-phosphate isomerase [Leishmania s...   689   0.0  
ref|YP_677101.1|  glucose-6-phosphate isomerase [Cytophaga h...   676   0.0  
sp|Q4R591|G6PI_MACFA  Glucose-6-phosphate isomerase (GPI) (P...   672   0.0  
ref|NP_001035561.1|  glucose phosphate isomerase [Bos taurus...   671   0.0  
pdb|1G98|A  Chain A, Crystal Structure Analysis Of Rabbit Ph...   671   0.0  
pdb|1DQR|A  Chain A, Crystal Structure Of Rabbit Phosphogluc...   671   0.0  
ref|NP_001075538.1|  phosphoglucose isomerase [Oryctolagus c...   671   0.0  
pdb|1N8T|A  Chain A, The Crystal Structure Of Phosphoglucose...   671   0.0  
ref|XP_867960.1|  PREDICTED: similar to Glucose-6-phosphate ...   670   0.0  
ref|NP_230028.1|  glucose-6-phosphate isomerase [Vibrio chol...   670   0.0  
ref|ZP_01682182.1|  glucose-6-phosphate isomerase [Vibrio ch...   670   0.0  
ref|ZP_01481622.1|  hypothetical protein VchoR_02002478 [Vib...   670   0.0  
gb|AAR89393.1|  glucose-6-phosphate isomerase [Trypanosoma c...   670   0.0  
dbj|BAF91562.1|  phosphoglucose isomerase [Lepisosteus osseus]    669   0.0  
ref|XP_867967.1|  PREDICTED: similar to Glucose-6-phosphate ...   669   0.0  
emb|CAC83783.1|  phosphoglucose isomerase [Bufo melanostictus]    669   0.0  
gb|EDN15559.1|  glucose-6-phosphate isomerase [Vibrio choler...   668   0.0  
ref|ZP_02133202.1|  Transketolase [Desulfatibacillum alkeniv...   668   0.0  
ref|NP_999495.1|  glucose phosphate isomerase [Sus scrofa] >...   667   0.0  
pdb|1GZD|A  Chain A, Crystal Structure Of Pig Phosphoglucose...   667   0.0  
ref|XP_853858.1|  PREDICTED: similar to Glucose-6-phosphate ...   667   0.0  
ref|NP_997475.1|  glucose phosphate isomerase [Rattus norveg...   667   0.0  
dbj|BAE23502.1|  unnamed protein product [Mus musculus]           666   0.0  
ref|YP_854687.1|  glucose-6-phosphate isomerase [Aeromonas h...   666   0.0  
gb|AAH83507.1|  Glucose phosphate isomerase a [Danio rerio]       665   0.0  
ref|XP_001599986.1|  PREDICTED: similar to phosphoglucose is...   665   0.0  
gb|AAR89395.1|  glucose-6-phosphate isomerase [Trypanosoma c...   665   0.0  
sp|P06745|G6PI_MOUSE  Glucose-6-phosphate isomerase (GPI) (P...   665   0.0  
ref|XP_623552.1|  PREDICTED: similar to Glucose-6-phosphate ...   664   0.0  
gb|AAP36518.1|  Homo sapiens glucose phosphate isomerase [sy...   664   0.0  
ref|NP_000166.2|  glucose phosphate isomerase [Homo sapiens]...   664   0.0  
pdb|1IAT|A  Chain A, Crystal Structure Of Human Phosphogluco...   664   0.0  
pdb|1JLH|A  Chain A, Human Glucose-6-Phosphate Isomerase >gi...   664   0.0  
dbj|BAF91557.1|  phosphoglucose isomerase-1 [Osteoglossum bi...   664   0.0  
ref|NP_001006128.1|  glucose phosphate isomerase [Gallus gal...   664   0.0  
emb|CAC83779.1|  phosphoglucose isomerase-2 [Mugil cephalus]      664   0.0  
ref|NP_032181.1|  glucose phosphate isomerase 1 [Mus musculu...   664   0.0  
ref|YP_001143911.1|  glucose-6-phosphate isomerase [Aeromona...   663   0.0  
gb|AAH44450.1|  Glucose phosphate isomerase a [Danio rerio]       663   0.0  
emb|CAP09263.1|  glucose phosphate isomerase b [Danio rerio]      663   0.0  
gb|ABB76196.1|  phosphoglucose isomerase [Colias eurytheme]       663   0.0  
dbj|BAE21866.1|  unnamed protein product [Mus musculus]           662   0.0  
dbj|BAE35416.1|  unnamed protein product [Mus musculus]           662   0.0  
dbj|BAE22329.1|  unnamed protein product [Mus musculus]           662   0.0  
gb|ABB00833.1|  phosphoglucose isomerase [Colias eurytheme]       662   0.0  
gb|AAF22645.1|AF187554_1  sperm antigen-36 [Homo sapiens]         662   0.0  
dbj|BAF91559.1|  phosphoglucose isomerase [Polypterus ornati...   662   0.0  
gb|ABB76190.1|  phosphoglucose isomerase [Colias eurytheme]       662   0.0  
dbj|BAF91556.1|  phosphoglucose isomerase [Amia calva]            662   0.0  
dbj|BAF91565.1|  phosphoglucose isomerase-1 [Plecoglossus al...   662   0.0  
gb|ABB76192.1|  phosphoglucose isomerase [Colias eurytheme]       661   0.0  
pdb|2CVP|A  Chain A, Crystal Structure Of Mouse Amf >gi|1091...   661   0.0  
gb|AAI21195.1|  Gpib protein [Danio rerio]                        661   0.0  
gb|ABB76199.1|  phosphoglucose isomerase [Colias eurytheme]       661   0.0  
pdb|1U0E|A  Chain A, Crystal Structure Of Mouse Phosphogluco...   661   0.0  
ref|XP_970258.1|  PREDICTED: similar to Glucose-6-phosphate ...   661   0.0  
gb|ABB76191.1|  phosphoglucose isomerase [Colias eurytheme]       661   0.0  
gb|AAA36368.1|  neuroleukin >gi|1336765|gb|AAB36062.1| gluco...   661   0.0  
gb|ABB76189.1|  phosphoglucose isomerase [Colias eurytheme]       661   0.0  
gb|ABH11445.1|  cytosolic glucose-6-phosphate isomerase [Pha...   661   0.0  
sp|Q5R4E3|G6PI_PONPY  Glucose-6-phosphate isomerase (GPI) (P...   660   0.0  
gb|ABH11436.1|  cytosolic glucose-6-phosphate isomerase [Pav...   660   0.0  
ref|NP_001085765.1|  MGC80718 protein [Xenopus laevis] >gi|4...   660   0.0  
gb|ABB76188.1|  phosphoglucose isomerase [Colias eurytheme]       660   0.0  
gb|ABB76195.1|  phosphoglucose isomerase [Colias eurytheme]       660   0.0  
gb|ABB76200.1|  phosphoglucose isomerase [Colias meadii]          659   0.0  
gb|ABB76201.1|  phosphoglucose isomerase [Colias meadii]          659   0.0  
prf||1405328A  phosphohexose isomerase                            659   0.0  
dbj|BAF91563.1|  phosphoglucose isomerase [Acipenser ruthenus]    659   0.0  
gb|ABB76197.1|  phosphoglucose isomerase [Colias eurytheme]       658   0.0  
dbj|BAF91566.1|  phosphoglucose isomerase-2 [Plecoglossus al...   658   0.0  
emb|CAC83778.1|  phosphoglucose isomerase [Mugil cephalus]        658   0.0  
ref|ZP_00055322.1|  COG0166: Glucose-6-phosphate isomerase [...   658   0.0  
ref|XP_001663180.1|  glucose-6-phosphate isomerase [Aedes ae...   658   0.0  
ref|YP_543532.1|  glucose-6-phosphate isomerase [Escherichia...   658   0.0  
ref|ZP_00724931.1|  COG0166: Glucose-6-phosphate isomerase [...   657   0.0  
dbj|BAF91560.1|  phosphoglucose isomerase-1 [Anguilla anguilla]   657   0.0  
ref|NP_658909.1|  glucose phosphate isomerase a [Danio rerio...   657   0.0  
dbj|BAF91558.1|  phosphoglucose isomerase-2 [Osteoglossum bi...   657   0.0  
gb|EEH96038.1|  glucose-6-phosphate isomerase [Citrobacter s...   657   0.0  
ref|NP_523663.1|  Phosphoglucose isomerase CG8251-PA, isofor...   657   0.0  
ref|YP_001746414.1|  glucose-6-phosphate isomerase [Escheric...   657   0.0  
gb|AAA28797.1|  glucosephosphate isomerase >gi|443615|gb|AAA...   657   0.0  
gb|AAA28804.1|  glucose-6-phosphate isomerase                     657   0.0  
gb|AAA63672.1|  glucosephosphate isomerase                        657   0.0  
gb|AAA28789.1|  glucosephosphate isomerase >gi|443601|gb|AAA...   657   0.0  
ref|YP_001909025.1|  Glucose-6-phosphate isomerase (Phosphog...   656   0.0  
gb|ABB76198.1|  phosphoglucose isomerase [Colias eurytheme]       656   0.0  
ref|NP_290659.1|  glucose-6-phosphate isomerase [Escherichia...   655   0.0  
ref|ZP_01720871.1|  glucose-6-phosphate isomerase [Algoripha...   655   0.0  
ref|ZP_00711964.1|  COG0166: Glucose-6-phosphate isomerase [...   655   0.0  
ref|XP_001490657.1|  PREDICTED: similar to Glucose phosphate...   655   0.0  
ref|XP_001848359.1|  glucose-6-phosphate isomerase [Culex pi...   655   0.0  
ref|ZP_03838871.1|  glucose-6-phosphate isomerase [Citrobact...   655   0.0  
ref|NP_799110.1|  glucose-6-phosphate isomerase [Vibrio para...   655   0.0  
sp|P52031|G6PI_DROYA  Glucose-6-phosphate isomerase (GPI) (P...   654   0.0  
ref|ZP_01237153.1|  glucose-6-phosphate isomerase [Vibrio an...   654   0.0  
ref|NP_838787.1|  glucose-6-phosphate isomerase [Shigella fl...   654   0.0  
emb|CAA33268.1|  unnamed protein product [Escherichia coli]       654   0.0  
ref|YP_001455405.1|  hypothetical protein CKO_03893 [Citroba...   654   0.0  
gb|AAA28809.1|  glucose-6-phosphate isomerase                     654   0.0  
ref|YP_691477.1|  glucose-6-phosphate isomerase [Shigella fl...   654   0.0  
gb|AAA28813.1|  glucose-6-phosphate isomerase                     654   0.0  
ref|ZP_02478614.1|  hypothetical protein HPS_11202 [Haemophi...   654   0.0  
sp|P52030|G6PI_DROSI  Glucose-6-phosphate isomerase (GPI) (P...   654   0.0  
ref|YP_001008017.1|  glucose-6-phosphate isomerase [Yersinia...   654   0.0  
ref|NP_658910.1|  glucose phosphate isomerase b [Danio rerio...   653   0.0  
sp|P50309|G6PI_CRIGR  Glucose-6-phosphate isomerase (GPI) (P...   653   0.0  
ref|YP_001338035.1|  glucose-6-phosphate isomerase [Klebsiel...   653   0.0  
ref|ZP_03900221.1|  glucose-6-phosphate isomerase [Dyadobact...   653   0.0  
ref|ZP_01215739.1|  glucose-6-phosphate isomerase [Psychromo...   653   0.0  
ref|ZP_02567671.1|  glucose-6-phosphate isomerase [Salmonell...   653   0.0  
ref|ZP_01162337.1|  glucose-6-phosphate isomerase [Photobact...   653   0.0  
ref|ZP_02680981.1|  hypothetical protein Sentericaenterica_2...   652   0.0  
ref|XP_320366.3|  AGAP012167-PA [Anopheles gambiae str. PEST...   652   0.0  
dbj|BAF91561.1|  phosphoglucose isomerase-2 [Anguilla anguilla]   652   0.0  
ref|NP_760318.1|  glucose-6-phosphate isomerase [Vibrio vuln...   652   0.0  
ref|ZP_02685434.1|  glucose-6-phosphate isomerase [Salmonell...   652   0.0  
ref|YP_001174971.1|  glucose-6-phosphate isomerase [Enteroba...   652   0.0  
ref|XP_001629102.1|  predicted protein [Nematostella vectens...   652   0.0  
ref|ZP_02644649.1|  hypothetical protein Senterenterica_0343...   652   0.0  
ref|ZP_02700747.1|  hypothetical protein Saentericaenterica_...   651   0.0  
ref|XP_001365167.1|  PREDICTED: similar to phosphoglucose is...   651   0.0  
ref|NP_001011010.1|  glucose phosphate isomerase [Xenopus tr...   651   0.0  
ref|NP_001091761.1|  glucose-6-phosphate isomerase [Bombyx m...   651   0.0  
ref|YP_219087.1|  glucose-6-phosphate isomerase [Salmonella ...   651   0.0  
ref|ZP_02903962.1|  glucose-6-phosphate isomerase [Escherich...   651   0.0  
gb|AAP33062.1|  phosphoglucose isomerase [Vibrio vulnificus]      651   0.0  
ref|YP_001572432.1|  hypothetical protein SARI_03461 [Salmon...   651   0.0  
ref|NP_458519.1|  glucose-6-phosphate isomerase [Salmonella ...   651   0.0  
ref|NP_931552.1|  glucose-6-phosphate isomerase [Photorhabdu...   651   0.0  
ref|NP_463086.1|  glucose-6-phosphate isomerase [Salmonella ...   651   0.0  
ref|ZP_02705383.1|  hypothetical protein Salmoentericaenteri...   651   0.0  
ref|NP_935768.1|  glucose-6-phosphate isomerase [Vibrio vuln...   650   0.0  
ref|ZP_02561519.1|  hypothetical protein Sente_14948 [Salmon...   650   0.0  
ref|ZP_02833339.1|  hypothetical protein Salentericaenterica...   650   0.0  
ref|ZP_01450980.1|  glucose-6-phosphate isomerase [Mariprofu...   650   0.0  
ref|YP_865849.1|  Glucose-6-phosphate isomerase [Magnetococc...   650   0.0  
emb|CAC83780.1|  phosphoglucose isomerase [Boiga kraepelini]      649   0.0  
ref|YP_153096.1|  glucose-6-phosphate isomerase [Salmonella ...   649   0.0  
ref|YP_001443299.1|  glucose-6-phosphate isomerase [Vibrio h...   649   0.0  
emb|CAC83777.1|  phosphoglucose isomerase [Paramyxine yangi]      649   0.0  
ref|ZP_01473793.1|  hypothetical protein VEx2w_02003634 [Vib...   649   0.0  
ref|XP_001510188.1|  PREDICTED: hypothetical protein [Ornith...   647   0.0  
sp|Q1H1P4|G6PI_METFK  Glucose-6-phosphate isomerase (GPI) (P...   647   0.0  
gb|ABH11435.2|  cytosolic glucose-6-phosphate isomerase [Emi...   647   0.0  
ref|NP_407169.1|  glucose-6-phosphate isomerase [Yersinia pe...   647   0.0  
ref|ZP_01869965.1|  glucose-6-phosphate isomerase [Vibrio sh...   647   0.0  
ref|ZP_01261693.1|  glucose-6-phosphate isomerase [Vibrio al...   647   0.0  
ref|YP_001436210.1|  hypothetical protein ESA_00069 [Enterob...   646   0.0  
ref|YP_113710.1|  glucose-6-phosphate isomerase [Methylococc...   646   0.0  
ref|YP_847696.1|  phosphoglucose isomerase (PGI) [Syntrophob...   646   0.0  
ref|ZP_02197004.1|  glucose-6-phosphate isomerase [Vibrio ca...   646   0.0  
ref|NP_994374.1|  glucose-6-phosphate isomerase [Yersinia pe...   645   0.0  
ref|ZP_03827475.1|  glucose-6-phosphate isomerase [Pectobact...   645   0.0  
ref|XP_001749895.1|  predicted protein [Monosiga brevicollis...   645   0.0  
ref|ZP_02961946.1|  hypothetical protein PROSTU_04029 [Provi...   645   0.0  
ref|YP_342945.1|  Glucose-6-phosphate isomerase [Nitrosococc...   644   0.0  
ref|YP_423777.1|  Glucose-6-phosphate isomerase [Magnetospir...   644   0.0  
ref|YP_001784733.1|  Glucose-6-phosphate isomerase [Haemophi...   644   0.0  
emb|CAJ73656.1|  strongly similar to glucose-6-phosphate iso...   644   0.0  
gb|EDN74431.1|  glucose-6-phosphate isomerase [Mannheimia ha...   643   0.0  
ref|YP_052066.1|  glucose-6-phosphate isomerase [Erwinia car...   643   0.0  
ref|ZP_01883305.1|  glucose-6-phosphate isomerase [Pedobacte...   642   0.0  
ref|YP_203687.1|  glucosephosphate isomerase [Vibrio fischer...   642   0.0  
gb|ABI49145.1|  glucose-6-phosphate isomerase [Trimastix pyr...   642   0.0  
ref|YP_001480699.1|  Glucose-6-phosphate isomerase [Serratia...   642   0.0  
gb|AAX73170.1|  putative glucose phosphate isomerase [Echino...   641   0.0  
ref|ZP_03830266.1|  glucose-6-phosphate isomerase [Pectobact...   641   0.0  
ref|ZP_00821566.1|  COG0166: Glucose-6-phosphate isomerase [...   640   0.0  
gb|ABS81352.1|  phosphoglucose isomerase [Echinococcus multi...   640   0.0  
ref|YP_941789.1|  Glucose-6-phosphate isomerase [Psychromona...   640   0.0  
ref|ZP_00531578.1|  Glucose-6-phosphate isomerase [Chlorobiu...   640   0.0  
ref|ZP_00828371.1|  COG0166: Glucose-6-phosphate isomerase [...   639   0.0  
ref|XP_001361508.1|  GA20931-PA [Drosophila pseudoobscura] >...   639   0.0  
ref|XP_867955.1|  PREDICTED: similar to Glucose-6-phosphate ...   639   0.0  
ref|YP_545434.1|  Glucose-6-phosphate isomerase [Methylobaci...   638   0.0  
ref|XP_638957.1|  glucose-6-phosphate isomerase [Dictyosteli...   636   e-180
ref|ZP_03842012.1|  glucose-6-phosphate isomerase [Proteus m...   636   e-180
ref|YP_001053832.1|  glucose-6-phosphate isomerase [Actinoba...   636   e-180
ref|YP_719149.1|  glucose-6-phosphate isomerase [Haemophilus...   636   e-180
ref|ZP_00824080.1|  COG0166: Glucose-6-phosphate isomerase [...   635   e-180
ref|ZP_01786798.1|  glucose-6-phosphate isomerase [Haemophil...   635   e-180
ref|ZP_00832585.1|  COG0166: Glucose-6-phosphate isomerase [...   635   e-180
ref|YP_001290850.1|  glucose-6-phosphate isomerase [Haemophi...   635   e-180
ref|ZP_01222432.1|  glucose-6-phosphate isomerase [Photobact...   635   e-180
ref|NP_872994.1|  glucose-6-phosphate isomerase [Haemophilus...   635   e-180
ref|YP_001652156.1|  glucose-6-phosphate isomerase [Actinoba...   634   e-180
ref|YP_001599432.1|  glucose-6-phosphate isomerase [Neisseri...   634   e-180
ref|ZP_00135214.1|  COG0166: Glucose-6-phosphate isomerase [...   634   e-180
ref|NP_899819.1|  glucose-6-phosphate isomerase [Chromobacte...   634   e-180
ref|ZP_01816475.1|  glucose-6-phosphate isomerase [Vibrional...   633   e-179
ref|YP_088373.1|  glucose-6-phosphate isomerase [Mannheimia ...   633   e-179
ref|ZP_00155145.1|  COG0166: Glucose-6-phosphate isomerase [...   633   e-179
ref|YP_455826.1|  glucose-6-phosphate isomerase [Sodalis glo...   633   e-179
ref|YP_207851.1|  glucose-6-phosphate isomerase [Neisseria g...   633   e-179
gb|AAX88290.1|  glucose-6-phosphate isomerase [Haemophilus i...   633   e-179
ref|YP_001344719.1|  Glucose-6-phosphate isomerase [Actinoba...   633   e-179
dbj|BAC36335.1|  unnamed protein product [Mus musculus]           633   e-179
ref|ZP_01066513.1|  glucose-6-phosphate isomerase [Vibrio sp...   632   e-179
ref|YP_248950.2|  glucose-6-phosphate isomerase [Haemophilus...   632   e-179
ref|ZP_01793484.1|  glucose-6-phosphate isomerase [Haemophil...   632   e-179
ref|NP_274402.1|  glucose-6-phosphate isomerase [Neisseria m...   632   e-179
gb|AAC23219.1|  glucose-6-phosphate isomerase (pgi) [Haemoph...   632   e-179
ref|ZP_00991932.1|  glucose-6-phosphate isomerase [Vibrio sp...   632   e-179
ref|YP_975337.1|  glucose-6-phosphate isomerase [Neisseria m...   632   e-179
ref|NP_284321.1|  glucose-6-phosphate isomerase [Neisseria m...   632   e-179
ref|ZP_01791410.1|  glucose-6-phosphate isomerase [Haemophil...   632   e-179
ref|ZP_00157128.2|  COG0166: Glucose-6-phosphate isomerase [...   632   e-179
ref|ZP_01795487.1|  glucose-6-phosphate isomerase [Haemophil...   631   e-179
ref|YP_131428.1|  glucose-6-phosphate isomerase [Photobacter...   631   e-179
ref|NP_439722.2|  glucose-6-phosphate isomerase [Haemophilus...   631   e-179
ref|YP_001291516.1|  glucose-6-phosphate isomerase [Haemophi...   631   e-179
ref|NP_245353.1|  glucose-6-phosphate isomerase [Pasteurella...   629   e-178
ref|ZP_01900582.1|  glucose-6-phosphate isomerase [Moritella...   628   e-178
ref|ZP_01788697.1|  glucose-6-phosphate isomerase [Haemophil...   628   e-178
ref|XP_001900986.1|  glucose phosphate isomerase a [Brugia m...   625   e-177
ref|ZP_01386716.1|  Glucose-6-phosphate isomerase [Chlorobiu...   623   e-176
ref|YP_375066.1|  Glucose-6-phosphate isomerase [Pelodictyon...   623   e-176
ref|ZP_00511177.1|  Glucose-6-phosphate isomerase [Chlorobiu...   623   e-176
sp|Q3B3Q8|G6PI_PELLD  Glucose-6-phosphate isomerase (GPI) (P...   622   e-176
ref|XP_650595.1|  glucose-6-phosphate isomerase, putative [E...   620   e-175
ref|NP_001021838.1|  Glucose-6-Phosphate Isomerase family me...   619   e-175
dbj|BAE53448.1|  Glucosephosphate isomerase [Entamoeba histo...   619   e-175
dbj|BAE53447.1|  Glucosephosphate isomerase [Entamoeba histo...   618   e-175
ref|NP_001021837.1|  Glucose-6-Phosphate Isomerase family me...   618   e-175
ref|YP_428031.1|  Glucose-6-phosphate isomerase [Rhodospiril...   617   e-174
emb|CAP27938.1|  C. briggsae CBR-GPI-1 protein [Caenorhabdit...   617   e-174
dbj|BAF57007.1|  glucose-6-phosphate isomerase 1 [Entamoeba ...   616   e-174
ref|XP_001741106.1|  glucose-6-phosphate isomerase, putative...   615   e-174
ref|YP_911560.1|  Glucose-6-phosphate isomerase [Chlorobium ...   615   e-174
ref|YP_001130308.1|  Glucose-6-phosphate isomerase [Prosthec...   614   e-174
dbj|BAF57008.1|  glucose-6-phosphate isomerase 2 [Entamoeba ...   613   e-174
ref|ZP_01797300.1|  glucose-6-phosphate isomerase [Haemophil...   613   e-173
gb|AAG15513.1|U65476_1  phosphoglucose isomerase; glucose-6-...   613   e-173
ref|NP_661881.1|  glucose-6-phosphate isomerase [Chlorobium ...   611   e-173
ref|YP_315821.1|  glucose-6-phosphate isomerase [Thiobacillu...   611   e-173
sp|Q3SH73|G6PI2_THIDA  Glucose-6-phosphate isomerase 2 (GPI ...   611   e-173
gb|AAT91251.1|  Glc-6-P isomerase [Paxillus involutus]            609   e-172
ref|NP_596635.1|  glucose-6-phosphate isomerase (predicted) ...   607   e-171
ref|XP_001732736.1|  hypothetical protein MGL_0511 [Malassez...   607   e-171
dbj|BAG13901.1|  glucose-6-phosphate isomerase [uncultured T...   607   e-171
ref|ZP_01088891.1|  glucose-6-phosphate isomerase [Blastopir...   606   e-171
ref|ZP_00588749.1|  Glucose-6-phosphate isomerase [Pelodicty...   606   e-171
ref|NP_295465.1|  glucose-6-phosphate isomerase [Deinococcus...   605   e-171
gb|EDM07646.1|  glucose phosphate isomerase [Rattus norvegicus]   604   e-171
ref|XP_001839617.1|  hypothetical protein CC1G_10610 [Coprin...   603   e-170
ref|XP_777368.1|  hypothetical protein CNBB1690 [Cryptococcu...   602   e-170
ref|ZP_00592941.1|  Glucose-6-phosphate isomerase [Prostheco...   602   e-170
ref|XP_569228.1|  glucose-6-phosphate isomerase [Cryptococcu...   602   e-170
dbj|BAA13929.1|  unnamed protein product [Schizosaccharomyce...   599   e-169
gb|AAO43937.1|  glucose phosphate isomerase [Trypanosoma cru...   598   e-169
ref|ZP_01552284.1|  Glucose-6-phosphate isomerase [Methyloph...   598   e-169
ref|XP_447033.1|  unnamed protein product [Candida glabrata]...   597   e-169
gb|AAO43957.1|  glucose phosphate isomerase [Trypanosoma cruzi]   597   e-169
ref|NP_009755.1|  Glycolytic enzyme phosphoglucose isomerase...   597   e-169
gb|AAO43953.1|  glucose phosphate isomerase [Trypanosoma cru...   597   e-169
gb|AAO43962.1|  glucose phosphate isomerase [Trypanosoma cruzi]   597   e-168
gb|AAO43946.1|  glucose phosphate isomerase [Trypanosoma cru...   597   e-168
ref|NP_924638.1|  glucose-6-phosphate isomerase [Gloeobacter...   596   e-168
gb|EDU44288.1|  glucose-6-phosphate isomerase [Pyrenophora t...   595   e-168
gb|AAO43952.1|  glucose phosphate isomerase [Trypanosoma cruzi]   595   e-168
ref|YP_378928.1|  glucose-6-phosphate isomerase [Chlorobium ...   595   e-168
>sp|P13377|G6PI_TRYBB Glucose-6-phosphate isomerase, glycosomal (GPI) (Phosphoglucose
           isomerase) (PGI) (Phosphohexose isomerase) (PHI)
 emb|CAA33547.1| unnamed protein product [Trypanosoma brucei]
          Length = 607

 Score = 1258 bits (3256), Expect = 0.0,   Method: Composition-based stats.
 Identities = 607/607 (100%), Positives = 607/607 (100%)

Query: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60
           MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ
Sbjct: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60

Query: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120
           KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA
Sbjct: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120

Query: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180
           EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF
Sbjct: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180

Query: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240
           SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI
Sbjct: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240

Query: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300
           AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS
Sbjct: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300

Query: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360
           TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF
Sbjct: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360

Query: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420
           ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS
Sbjct: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420

Query: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480
           GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF
Sbjct: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480

Query: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540
           FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG
Sbjct: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540

Query: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600
           AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM
Sbjct: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600

Query: 601 FNELSHL 607
           FNELSHL
Sbjct: 601 FNELSHL 607
>pdb|2O2C|A Chain A, Crystal Structure Of Phosphoglucose Isomerase From T.
           Brucei Containing Glucose-6-Phosphate In The Active Site
 pdb|2O2C|B Chain B, Crystal Structure Of Phosphoglucose Isomerase From T.
           Brucei Containing Glucose-6-Phosphate In The Active Site
 pdb|2O2C|C Chain C, Crystal Structure Of Phosphoglucose Isomerase From T.
           Brucei Containing Glucose-6-Phosphate In The Active Site
 pdb|2O2D|A Chain A, Crystal Structure Of Phosphoglucose Isomerase From
           Trypanosoma Brucei Complexed With Citrate
 pdb|2O2D|B Chain B, Crystal Structure Of Phosphoglucose Isomerase From
           Trypanosoma Brucei Complexed With Citrate
 pdb|2O2D|C Chain C, Crystal Structure Of Phosphoglucose Isomerase From
           Trypanosoma Brucei Complexed With Citrate
          Length = 613

 Score = 1252 bits (3239), Expect = 0.0,   Method: Composition-based stats.
 Identities = 604/605 (99%), Positives = 604/605 (99%)

Query: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60
           MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ
Sbjct: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60

Query: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120
           KLYEQYGDEPIKKHFE DSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA
Sbjct: 61  KLYEQYGDEPIKKHFETDSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120

Query: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180
           EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF
Sbjct: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180

Query: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240
           SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI
Sbjct: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240

Query: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300
           AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS
Sbjct: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300

Query: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360
           TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF
Sbjct: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360

Query: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420
           ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS
Sbjct: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420

Query: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480
           GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF
Sbjct: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480

Query: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540
           FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG
Sbjct: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540

Query: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600
           AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM
Sbjct: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600

Query: 601 FNELS 605
           FNELS
Sbjct: 601 FNELS 605
>ref|XP_001219077.1| glucose-6-phosphate isomerase, glycosomal [Trypanosoma brucei]
 emb|CAJ16590.1| glucose-6-phosphate isomerase, glycosomal [Trypanosoma brucei]
          Length = 607

 Score = 1251 bits (3236), Expect = 0.0,   Method: Composition-based stats.
 Identities = 603/607 (99%), Positives = 605/607 (99%)

Query: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60
           MS+YLDDLR+ LAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ
Sbjct: 1   MSNYLDDLRMHLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60

Query: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120
           KLYEQYGDEPIKKHFE DSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA
Sbjct: 61  KLYEQYGDEPIKKHFETDSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120

Query: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180
           EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF
Sbjct: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180

Query: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240
           SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI
Sbjct: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240

Query: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300
           AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS
Sbjct: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300

Query: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360
           TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF
Sbjct: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360

Query: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420
           ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS
Sbjct: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420

Query: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480
           GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF
Sbjct: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480

Query: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540
           FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG
Sbjct: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540

Query: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600
           AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM
Sbjct: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600

Query: 601 FNELSHL 607
           FNELSHL
Sbjct: 601 FNELSHL 607
>ref|XP_820895.1| glucose-6-phosphate isomerase, glycosomal, putative [Trypanosoma
           cruzi strain CL Brener]
 gb|EAN99044.1| glucose-6-phosphate isomerase, glycosomal, putative [Trypanosoma
           cruzi]
          Length = 608

 Score =  961 bits (2485), Expect = 0.0,   Method: Composition-based stats.
 Identities = 447/604 (74%), Positives = 524/604 (86%)

Query: 4   YLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLY 63
           YL DL + L  S A+  + S+AV SFN+P+E+TRR++ +G D DT+L+SC SW +LQ+LY
Sbjct: 5   YLKDLTVHLNESNAAPANTSMAVASFNMPHEITRRMRPLGVDTDTSLSSCPSWRRLQELY 64

Query: 64  EQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLAEER 123
           E +G E I K+F+   +R QRYS++V L S D+NF+FLDYSK+HINDEIK  L +L EER
Sbjct: 65  EIHGSESILKNFDECKDRFQRYSLEVDLRSSDKNFVFLDYSKTHINDEIKDVLFKLVEER 124

Query: 124 GIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEK 183
           GIR F++++F GE+VNT ENR VLHIALRNRSNRPI+VDG DVMP VNKVL+QM+  SEK
Sbjct: 125 GIRAFMRALFAGEKVNTAENRSVLHIALRNRSNRPIFVDGHDVMPMVNKVLEQMKKISEK 184

Query: 184 VRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEV 243
           VR GEWKG +GK IRHVVNIGIGGSDLGP+MA EALKPFS R +S+HFVSN+DGTH++EV
Sbjct: 185 VRRGEWKGQSGKPIRHVVNIGIGGSDLGPMMACEALKPFSDRRISMHFVSNIDGTHLSEV 244

Query: 244 LKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALSTNN 303
           LK +D+E+TLFI+ASKTFTTQETITNALSAR   L +L SRGI E G+VAKHFVALSTN 
Sbjct: 245 LKLVDLESTLFIIASKTFTTQETITNALSARSEFLKFLSSRGIPEAGAVAKHFVALSTNA 304

Query: 304 QKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHFANA 363
           +KVKEFGIDE NMFQFWDWVGGRYS+WSAIGL +MISIGY+NFVE LTGAH++DEHF NA
Sbjct: 305 EKVKEFGIDEANMFQFWDWVGGRYSLWSAIGLSVMISIGYDNFVEFLTGAHIMDEHFINA 364

Query: 364 PPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKT 423
           P E N+P++LALVG+WY NFFG+ T AILPYDQYLWRLPAYLQQLDMESNGK  T++G+ 
Sbjct: 365 PTENNLPIILALVGIWYNNFFGSETQAILPYDQYLWRLPAYLQQLDMESNGKGATKNGRM 424

Query: 424 VSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQ 483
           VST TGPIIFGEAGTNGQHAFYQLIHQGT LIPCDFIGAIQ+QN IG+HH+I MSNFFAQ
Sbjct: 425 VSTHTGPIIFGEAGTNGQHAFYQLIHQGTKLIPCDFIGAIQTQNYIGEHHRILMSNFFAQ 484

Query: 484 TEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALGAII 543
           TEALMIGK+P EV+RELE+AG +S ++I  L+P KTF GGRPSN+LL+K+LTPRALGAII
Sbjct: 485 TEALMIGKTPEEVKRELESAGGKSEDEIQLLIPQKTFTGGRPSNSLLVKALTPRALGAII 544

Query: 544 AMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNE 603
           AMYEHKVLVQGAIWGI+SYDQWGVELGK+LAKSILPQL+PG +V NHDSSTNGLI +FNE
Sbjct: 545 AMYEHKVLVQGAIWGINSYDQWGVELGKLLAKSILPQLQPGQKVTNHDSSTNGLIKLFNE 604

Query: 604 LSHL 607
            SHL
Sbjct: 605 RSHL 608
>ref|XP_821969.1| glucose-6-phosphate isomerase, glycosomal, putative [Trypanosoma
           cruzi strain CL Brener]
 gb|AAN78341.1| TcC31.19 [Trypanosoma cruzi]
 gb|EAO00118.1| glucose-6-phosphate isomerase, glycosomal, putative [Trypanosoma
           cruzi]
          Length = 608

 Score =  959 bits (2478), Expect = 0.0,   Method: Composition-based stats.
 Identities = 447/604 (74%), Positives = 525/604 (86%)

Query: 4   YLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLY 63
           YL DL + L  S A+  + S+AV SFN+P+E+TRR++ +G DADT+LTSC SW +LQ+LY
Sbjct: 5   YLKDLTVHLNESNAAPANTSMAVASFNMPHEITRRMRPLGVDADTSLTSCPSWRRLQELY 64

Query: 64  EQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLAEER 123
           E +G E I K+F+   +R QRYS++V L S D+NF+FLDYSK+HINDEIK  L +L EER
Sbjct: 65  EIHGSESILKNFDECKDRFQRYSLEVDLRSSDKNFVFLDYSKTHINDEIKDVLFKLVEER 124

Query: 124 GIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEK 183
           GIR F++++F GE+VNT ENR VLHIALRNRSNRPI+V+G DVMP VNKVL+QM+  SEK
Sbjct: 125 GIRAFMRALFAGEKVNTAENRSVLHIALRNRSNRPIFVNGHDVMPLVNKVLEQMKKLSEK 184

Query: 184 VRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEV 243
           VR GEWKG +GK IRHVVNIGIGGSDLGP+MA EAL+PFS R +S+HFVSN+DGTH++EV
Sbjct: 185 VRRGEWKGQSGKPIRHVVNIGIGGSDLGPMMACEALRPFSDRRISMHFVSNIDGTHLSEV 244

Query: 244 LKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALSTNN 303
           L  +D+E+TLFI+ASKTFTTQETITNALSAR   L +L SRGI E G+VAKHFVALSTN 
Sbjct: 245 LNLVDLESTLFIIASKTFTTQETITNALSARNEFLKFLSSRGISEAGAVAKHFVALSTNA 304

Query: 304 QKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHFANA 363
           +KVKEFGIDEENMFQFWDWVGGRYS+WSAIGL +MISIGY+NFVELLTGAH++DEHF NA
Sbjct: 305 EKVKEFGIDEENMFQFWDWVGGRYSLWSAIGLSVMISIGYDNFVELLTGAHIMDEHFINA 364

Query: 364 PPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKT 423
           P E N+P++LALVG+WY NFFG+ T AILPYDQYLWRLPAYLQQLDMESNGK  T++G+ 
Sbjct: 365 PTENNLPIILALVGIWYNNFFGSETQAILPYDQYLWRLPAYLQQLDMESNGKGATKNGRM 424

Query: 424 VSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQ 483
           VST TGPIIFGEAGTNGQHAFYQLIHQGT LIPCDFIGAIQ+QN IG+HH+I MSNFFAQ
Sbjct: 425 VSTHTGPIIFGEAGTNGQHAFYQLIHQGTKLIPCDFIGAIQTQNYIGEHHRILMSNFFAQ 484

Query: 484 TEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALGAII 543
           TEALMIGK+P EV+RELE+AG +S ++I  L+P KTF GGRPSN+LL+K+LTPRALGAII
Sbjct: 485 TEALMIGKTPEEVKRELESAGGKSEDEIQLLIPQKTFTGGRPSNSLLVKALTPRALGAII 544

Query: 544 AMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNE 603
           AMYEHKVLVQGAIWGI+SYDQWGVELGK+LAKSIL QL+PG +V NHDSSTNGLI +FNE
Sbjct: 545 AMYEHKVLVQGAIWGINSYDQWGVELGKLLAKSILLQLQPGQKVTNHDSSTNGLIELFNE 604

Query: 604 LSHL 607
            SHL
Sbjct: 605 RSHL 608
>emb|CAF05827.1| glucose-6-phosphate isomerase [Leishmania donovani]
          Length = 605

 Score =  899 bits (2322), Expect = 0.0,   Method: Composition-based stats.
 Identities = 426/608 (70%), Positives = 509/608 (83%), Gaps = 4/608 (0%)

Query: 1   MSSYLDDLRID-LAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQL 59
           MS YL  L+   L ++  +G + S+A  +FN PYEV RR K +GA  D++L S  +W +L
Sbjct: 1   MSDYLSKLKXHVLESTEVNGCTPSMATSTFNAPYEVARRTKVLGA-TDSSLLSLPAWKRL 59

Query: 60  QKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRL 119
           Q LYE++G+E I  HFE D +R  RYS++V L S +ENFLFLDYSKSHINDEIK AL+ L
Sbjct: 60  QSLYEKHGNESILSHFENDHQRFGRYSIEVGLHS-EENFLFLDYSKSHINDEIKDALVAL 118

Query: 120 AEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRS 179
           AEERG+R F +++F G+RVN+TENR VLH+ALRNRSNRPI VDGKDVM  VN VL QM+ 
Sbjct: 119 AEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDVMTDVNNVLAQMKD 178

Query: 180 FSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTH 239
           F+EKVR+GEWKG TGK+I ++VNIGIGGSDLGPVM TEALKPFS+RD+   FVSNVDGTH
Sbjct: 179 FTEKVRSGEWKGQTGKSISNIVNIGIGGSDLGPVMVTEALKPFSKRDMHCFFVSNVDGTH 238

Query: 240 IAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVAL 299
           +AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+DYL++  I   G+VAKHFVAL
Sbjct: 239 MAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMDYLKANNISTDGAVAKHFVAL 298

Query: 300 STNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEH 359
           STN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NFVE LTGAHV+D H
Sbjct: 299 STNTEKVREFGIDTVNMFVFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNH 358

Query: 360 FANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTR 419
           FA+AP EQN+P++LALVG+WY NFFGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+
Sbjct: 359 FASAPTEQNLPMMLALVGIWYNNFFGAETEAVLPYDQYLWRLPAYLQQLDMESNGKGVTK 418

Query: 420 SGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSN 479
               V+  TGPIIFGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSN
Sbjct: 419 KSGAVAVQTGPIIFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSN 478

Query: 480 FFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRAL 539
           FFAQTEALM+GKS  EVR+EL  +G  S E I +++PHKTF G RPSN++L+ +LTPRAL
Sbjct: 479 FFAQTEALMVGKSAEEVRQELAKSG-MSDEAIQSMIPHKTFTGNRPSNSILVNALTPRAL 537

Query: 540 GAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLIN 599
           GAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  V++HD STNGLIN
Sbjct: 538 GAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLIN 597

Query: 600 MFNELSHL 607
           MFN  +HL
Sbjct: 598 MFNTRAHL 605
>emb|CAF05824.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05840.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05841.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05842.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAJ40959.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAJ40960.1| glucose-6-phosphate isomerase [Leishmania donovani]
          Length = 605

 Score =  898 bits (2320), Expect = 0.0,   Method: Composition-based stats.
 Identities = 426/608 (70%), Positives = 509/608 (83%), Gaps = 4/608 (0%)

Query: 1   MSSYLDDLRID-LAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQL 59
           MS YL  L+   L ++  +G + S+A  +FN PYEV RR K +GA  D++L S  +W +L
Sbjct: 1   MSDYLSKLKKHVLESTEVNGCTPSMATSTFNAPYEVARRTKVLGA-TDSSLLSLPAWKRL 59

Query: 60  QKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRL 119
           Q LYE++G+E I  HFE D +R  RYS++V L S +ENFLFLDYSKSHINDEIK AL+ L
Sbjct: 60  QSLYEKHGNESILSHFENDHQRFGRYSIEVGLHS-EENFLFLDYSKSHINDEIKDALVAL 118

Query: 120 AEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRS 179
           AEERG+R F +++F G+RVN+TENR VLH+ALRNRSNRPI VDGKDVM  VN VL QM+ 
Sbjct: 119 AEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDVMTDVNNVLAQMKD 178

Query: 180 FSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTH 239
           F+EKVR+GEWKG TGK+I ++VNIGIGGSDLGPVM TEALKPFS+RD+   FVSNVDGTH
Sbjct: 179 FTEKVRSGEWKGQTGKSISNIVNIGIGGSDLGPVMVTEALKPFSKRDMHCFFVSNVDGTH 238

Query: 240 IAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVAL 299
           +AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+DYL++  I   G+VAKHFVAL
Sbjct: 239 MAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMDYLKANNISTDGAVAKHFVAL 298

Query: 300 STNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEH 359
           STN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NFVE LTGAHV+D H
Sbjct: 299 STNTEKVREFGIDTVNMFVFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNH 358

Query: 360 FANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTR 419
           FA+AP EQN+P++LALVG+WY NFFGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+
Sbjct: 359 FASAPTEQNLPMMLALVGIWYNNFFGAETEAVLPYDQYLWRLPAYLQQLDMESNGKGVTK 418

Query: 420 SGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSN 479
               V+  TGPIIFGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSN
Sbjct: 419 KSGAVAVQTGPIIFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSN 478

Query: 480 FFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRAL 539
           FFAQTEALM+GKS  EVR+EL  +G  S E I +++PHKTF G RPSN++L+ +LTPRAL
Sbjct: 479 FFAQTEALMVGKSAEEVRQELAKSG-MSDEAIQSMIPHKTFTGNRPSNSILVNALTPRAL 537

Query: 540 GAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLIN 599
           GAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  V++HD STNGLIN
Sbjct: 538 GAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLIN 597

Query: 600 MFNELSHL 607
           MFN  +HL
Sbjct: 598 MFNTRAHL 605
>ref|XP_001463984.1| glucose-6-phosphate isomerase [Leishmania infantum JPCM5]
 emb|CAF05816.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAF05820.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05838.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05817.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAF05818.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAF05821.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05822.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05823.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05825.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAF05826.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05828.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05832.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAF05833.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05834.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05835.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05836.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAF05837.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05843.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05844.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAF05846.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAJ40957.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAJ40958.1| glucose-6-phosphate isomerase [Leishmania donovani]
 emb|CAJ43255.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAJ43256.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAJ43257.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAJ43258.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAJ43259.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAM66358.1| glucose-6-phosphate isomerase [Leishmania infantum]
          Length = 605

 Score =  898 bits (2320), Expect = 0.0,   Method: Composition-based stats.
 Identities = 426/608 (70%), Positives = 509/608 (83%), Gaps = 4/608 (0%)

Query: 1   MSSYLDDLRID-LAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQL 59
           MS YL  L+   L ++  +G + S+A  +FN PYEV RR K +GA  D++L S  +W +L
Sbjct: 1   MSDYLSKLKEHVLESTEVNGCTPSMATSTFNAPYEVARRTKVLGA-TDSSLLSLPAWKRL 59

Query: 60  QKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRL 119
           Q LYE++G+E I  HFE D +R  RYS++V L S +ENFLFLDYSKSHINDEIK AL+ L
Sbjct: 60  QSLYEKHGNESILSHFENDHQRFGRYSIEVGLHS-EENFLFLDYSKSHINDEIKDALVAL 118

Query: 120 AEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRS 179
           AEERG+R F +++F G+RVN+TENR VLH+ALRNRSNRPI VDGKDVM  VN VL QM+ 
Sbjct: 119 AEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDVMTDVNNVLAQMKD 178

Query: 180 FSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTH 239
           F+EKVR+GEWKG TGK+I ++VNIGIGGSDLGPVM TEALKPFS+RD+   FVSNVDGTH
Sbjct: 179 FTEKVRSGEWKGQTGKSISNIVNIGIGGSDLGPVMVTEALKPFSKRDMHCFFVSNVDGTH 238

Query: 240 IAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVAL 299
           +AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+DYL++  I   G+VAKHFVAL
Sbjct: 239 MAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMDYLKANNISTDGAVAKHFVAL 298

Query: 300 STNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEH 359
           STN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NFVE LTGAHV+D H
Sbjct: 299 STNTEKVREFGIDTVNMFVFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNH 358

Query: 360 FANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTR 419
           FA+AP EQN+P++LALVG+WY NFFGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+
Sbjct: 359 FASAPTEQNLPMMLALVGIWYNNFFGAETEAVLPYDQYLWRLPAYLQQLDMESNGKGVTK 418

Query: 420 SGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSN 479
               V+  TGPIIFGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSN
Sbjct: 419 KSGAVAVQTGPIIFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSN 478

Query: 480 FFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRAL 539
           FFAQTEALM+GKS  EVR+EL  +G  S E I +++PHKTF G RPSN++L+ +LTPRAL
Sbjct: 479 FFAQTEALMVGKSAEEVRQELAKSG-MSDEAIQSMIPHKTFTGNRPSNSILVNALTPRAL 537

Query: 540 GAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLIN 599
           GAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  V++HD STNGLIN
Sbjct: 538 GAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLIN 597

Query: 600 MFNELSHL 607
           MFN  +HL
Sbjct: 598 MFNTRAHL 605
>emb|CAF05839.1| glucose-6-phosphate isomerase [Leishmania donovani]
          Length = 605

 Score =  895 bits (2314), Expect = 0.0,   Method: Composition-based stats.
 Identities = 425/608 (69%), Positives = 508/608 (83%), Gaps = 4/608 (0%)

Query: 1   MSSYLDDLRID-LAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQL 59
           MS YL  L+   L ++  +G + S+A  +FN PYEV RR K +GA  D++L S  +W +L
Sbjct: 1   MSDYLSKLKEHVLESTEVNGCTPSMATSTFNAPYEVARRTKVLGA-TDSSLLSLPAWKRL 59

Query: 60  QKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRL 119
           Q LYE++G+E I  HFE D +R  RYS++V L S +ENFLFLDYSKSHINDEIK AL+ L
Sbjct: 60  QSLYEKHGNESILSHFENDHQRFGRYSIEVGLHS-EENFLFLDYSKSHINDEIKDALVAL 118

Query: 120 AEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRS 179
           AEERG+R F +++F G+RVN+TENR VLH+ALRNRSNRPI VDGKDVM  VN VL QM+ 
Sbjct: 119 AEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDVMTDVNNVLAQMKD 178

Query: 180 FSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTH 239
           F+EKVR+GEWKG TGK+I ++VNIGIGGSDLGPVM TEALKPF +RD+   FVSNVDGTH
Sbjct: 179 FTEKVRSGEWKGQTGKSISNIVNIGIGGSDLGPVMVTEALKPFFKRDMHCFFVSNVDGTH 238

Query: 240 IAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVAL 299
           +AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+DYL++  I   G+VAKHFVAL
Sbjct: 239 MAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMDYLKANNISTDGAVAKHFVAL 298

Query: 300 STNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEH 359
           STN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NFVE LTGAHV+D H
Sbjct: 299 STNTEKVREFGIDTVNMFVFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNH 358

Query: 360 FANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTR 419
           FA+AP EQN+P++LALVG+WY NFFGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+
Sbjct: 359 FASAPTEQNLPMMLALVGIWYNNFFGAETEAVLPYDQYLWRLPAYLQQLDMESNGKGVTK 418

Query: 420 SGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSN 479
               V+  TGPIIFGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSN
Sbjct: 419 KSGAVAVQTGPIIFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSN 478

Query: 480 FFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRAL 539
           FFAQTEALM+GKS  EVR+EL  +G  S E I +++PHKTF G RPSN++L+ +LTPRAL
Sbjct: 479 FFAQTEALMVGKSAEEVRQELAKSG-MSDEAIQSMIPHKTFTGNRPSNSILVNALTPRAL 537

Query: 540 GAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLIN 599
           GAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  V++HD STNGLIN
Sbjct: 538 GAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLIN 597

Query: 600 MFNELSHL 607
           MFN  +HL
Sbjct: 598 MFNTRAHL 605
>emb|CAF05831.1| glucose-6-phosphate isomerase [Leishmania infantum]
          Length = 605

 Score =  895 bits (2313), Expect = 0.0,   Method: Composition-based stats.
 Identities = 425/608 (69%), Positives = 508/608 (83%), Gaps = 4/608 (0%)

Query: 1   MSSYLDDLRID-LAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQL 59
           MS YL  L+   L ++  +G + S+A  +FN PYEV RR K +GA  D++L S  +W +L
Sbjct: 1   MSDYLSKLKEHVLESTEVNGCTPSMATSTFNAPYEVARRTKVLGA-TDSSLLSLPAWKRL 59

Query: 60  QKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRL 119
           Q LYE++G+E I  HFE D +R  RYS++V L S +ENFLFLDYSKSHINDEIK AL+ L
Sbjct: 60  QSLYEKHGNESILSHFENDHQRFGRYSIEVGLHS-EENFLFLDYSKSHINDEIKDALVAL 118

Query: 120 AEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRS 179
           AEERG+R F +++F G+RVN+TENR VLH+ALRNRSNRPI VDGKDVM  VN VL QM+ 
Sbjct: 119 AEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDVMTDVNNVLAQMKD 178

Query: 180 FSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTH 239
           F+EKVR+GEWKG TGK+I ++VNIGIGGSDLGPVM TEALKPFS+RD+   FVSNVDGTH
Sbjct: 179 FTEKVRSGEWKGQTGKSISNIVNIGIGGSDLGPVMVTEALKPFSKRDMHCFFVSNVDGTH 238

Query: 240 IAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVAL 299
           +AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+DYL++  I   G+VAKHFVAL
Sbjct: 239 MAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMDYLKANNISTDGAVAKHFVAL 298

Query: 300 STNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEH 359
           STN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NFVE LTGAHV+D H
Sbjct: 299 STNTEKVREFGIDTVNMFVFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNH 358

Query: 360 FANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTR 419
           FA+AP EQN+P++LALVG+WY NFFGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+
Sbjct: 359 FASAPTEQNLPMMLALVGIWYNNFFGAETEAVLPYDQYLWRLPAYLQQLDMESNGKGVTK 418

Query: 420 SGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSN 479
               V+  TGPIIFGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSN
Sbjct: 419 KSGAVAVQTGPIIFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSN 478

Query: 480 FFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRAL 539
           FFAQTEALM+GKS  EV +EL  +G  S E I +++PHKTF G RPSN++L+ +LTPRAL
Sbjct: 479 FFAQTEALMVGKSAEEVXQELAKSG-MSDEAIQSMIPHKTFTGNRPSNSILVNALTPRAL 537

Query: 540 GAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLIN 599
           GAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  V++HD STNGLIN
Sbjct: 538 GAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLIN 597

Query: 600 MFNELSHL 607
           MFN  +HL
Sbjct: 598 MFNTRAHL 605
>emb|CAF05819.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAF05829.1| glucose-6-phosphate isomerase [Leishmania infantum]
 emb|CAF05830.1| glucose-6-phosphate isomerase [Leishmania infantum]
          Length = 605

 Score =  895 bits (2312), Expect = 0.0,   Method: Composition-based stats.
 Identities = 425/608 (69%), Positives = 508/608 (83%), Gaps = 4/608 (0%)

Query: 1   MSSYLDDLRID-LAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQL 59
           MS YL  L+   L ++  +G + S+A  +FN PYEV RR K +GA  D++L S  +W +L
Sbjct: 1   MSDYLSKLKEHVLESTEVNGCTPSMATSTFNAPYEVARRTKVLGA-TDSSLLSLPAWKRL 59

Query: 60  QKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRL 119
           Q LYE++G+E I  HFE D +R  RYS++V L S +ENFLFLDYSKSHINDEIK AL+ L
Sbjct: 60  QSLYEKHGNESILSHFENDHQRFGRYSIEVGLHS-EENFLFLDYSKSHINDEIKDALVAL 118

Query: 120 AEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRS 179
           AEERG+R F +++F G+RVN+TENR VLH+ALRNRSNRPI VDGKDVM  VN VL QM+ 
Sbjct: 119 AEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDVMTDVNNVLAQMKD 178

Query: 180 FSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTH 239
           F+EKVR+GEWKG TGK+I ++VNIGIGGSDLGPVM TEALKPFS+RD+   FVSNVDGTH
Sbjct: 179 FTEKVRSGEWKGQTGKSISNIVNIGIGGSDLGPVMVTEALKPFSKRDMHCFFVSNVDGTH 238

Query: 240 IAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVAL 299
           +AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+DYL++  I   G+VAKHFVAL
Sbjct: 239 MAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMDYLKANNISTDGAVAKHFVAL 298

Query: 300 STNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEH 359
           STN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NFVE LTGAHV+D H
Sbjct: 299 STNTEKVREFGIDTVNMFVFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNH 358

Query: 360 FANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTR 419
           FA+AP EQN+P++LALVG+WY NFFGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+
Sbjct: 359 FASAPTEQNLPMMLALVGIWYNNFFGAETEAVLPYDQYLWRLPAYLQQLDMESNGKGVTK 418

Query: 420 SGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSN 479
               V+  TGPIIFGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSN
Sbjct: 419 KSGAVAVQTGPIIFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSN 478

Query: 480 FFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRAL 539
           FFAQTEALM+GKS  EV +EL  +G  S E I +++PHKTF G RPSN++L+ +LTPRAL
Sbjct: 479 FFAQTEALMVGKSAEEVLQELAKSG-MSDEAIQSMIPHKTFTGNRPSNSILVNALTPRAL 537

Query: 540 GAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLIN 599
           GAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  V++HD STNGLIN
Sbjct: 538 GAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLIN 597

Query: 600 MFNELSHL 607
           MFN  +HL
Sbjct: 598 MFNTRAHL 605
>ref|XP_001681659.1| glucose-6-phosphate isomerase [Leishmania major]
 emb|CAJ02649.1| glucose-6-phosphate isomerase [Leishmania major]
 emb|CAF05845.1| glucose-6-phosphate isomerase [Leishmania major]
          Length = 605

 Score =  890 bits (2301), Expect = 0.0,   Method: Composition-based stats.
 Identities = 422/608 (69%), Positives = 508/608 (83%), Gaps = 4/608 (0%)

Query: 1   MSSYLDDLR-IDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQL 59
           MS YL  L+   L ++  +G + S+A  +FN PYEV RR K +GA  D++L S  +W +L
Sbjct: 1   MSDYLSKLKEYVLESTEVNGCAPSMATSTFNAPYEVARRTKMLGA-TDSSLLSLPAWKRL 59

Query: 60  QKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRL 119
           Q LYE++G+E I  HFE+D +R  RYS++V L S+D NFLFLDYSKSHINDEIK AL+ L
Sbjct: 60  QSLYEKHGNESILSHFESDHQRFGRYSIEVGLHSED-NFLFLDYSKSHINDEIKDALVAL 118

Query: 120 AEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRS 179
           AEERG+R F +++F G+RVN+TE+R VLH+ALRNRSNRPI VDGKDVM  VN VL QM++
Sbjct: 119 AEERGVRAFAKAMFDGQRVNSTEDRAVLHVALRNRSNRPIIVDGKDVMTDVNNVLAQMKN 178

Query: 180 FSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTH 239
           F+EKVR+GEWKG TGK+I ++VNIGIGGSDLGPVM TEALKPFS+RD+   FVSNVDGTH
Sbjct: 179 FTEKVRSGEWKGQTGKSISNIVNIGIGGSDLGPVMVTEALKPFSKRDMHCFFVSNVDGTH 238

Query: 240 IAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVAL 299
           +AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+DYL++  I   G+VAKHFVAL
Sbjct: 239 MAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMDYLKAHNISTDGAVAKHFVAL 298

Query: 300 STNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEH 359
           STN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NFVE LTGAHV+D H
Sbjct: 299 STNTEKVREFGIDTVNMFVFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNH 358

Query: 360 FANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTR 419
           FA+ P EQN+P++LALVG+WY NFFGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+
Sbjct: 359 FASTPTEQNLPMMLALVGIWYNNFFGAETEAVLPYDQYLWRLPAYLQQLDMESNGKGVTK 418

Query: 420 SGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSN 479
               V+  TG IIFGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSN
Sbjct: 419 KSAAVAVQTGSIIFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSN 478

Query: 480 FFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRAL 539
           FFAQTEALM+GKS  EVR+EL  +G  S E +  ++PHKTF G RPSN++L+ +LTPRAL
Sbjct: 479 FFAQTEALMVGKSAEEVRQELVKSG-MSGEAMERMIPHKTFTGNRPSNSILVNALTPRAL 537

Query: 540 GAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLIN 599
           GAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  V++HD STNGLIN
Sbjct: 538 GAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLIN 597

Query: 600 MFNELSHL 607
           MFN  +HL
Sbjct: 598 MFNTRAHL 605
>sp|P42861|G6PI_LEIME Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 pdb|1T10|A Chain A, Phosphoglucose Isomerase From Leishmania Mexicana In
           Complex With Substrate D-Fructose-6-Phosphate
 emb|CAA55042.1| glucose-6-phosphate isomerase [Leishmania mexicana mexicana]
          Length = 605

 Score =  887 bits (2293), Expect = 0.0,   Method: Composition-based stats.
 Identities = 417/608 (68%), Positives = 503/608 (82%), Gaps = 4/608 (0%)

Query: 1   MSSYLDDLRIDLAASPA-SGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQL 59
           MS Y   L+  +  S   +G + SIA  +FN PYEV R+ K +G   D++L +  +W +L
Sbjct: 1   MSDYFSKLKEHVVESTEINGCTPSIATATFNAPYEVARKTKMLGV-TDSSLLNLPAWKRL 59

Query: 60  QKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRL 119
           Q LYE+YG++ I  HFE D +R QRYS+++ L S D+NFLFLDYSKSHINDEIK AL+ L
Sbjct: 60  QSLYEKYGNDSILSHFEKDHQRFQRYSIEIDLHS-DDNFLFLDYSKSHINDEIKDALVAL 118

Query: 120 AEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRS 179
           AEERG+R F +++F G+RVN+TENR VLH+ALRNRSNRPI VDGKDVM  VN VL QM+ 
Sbjct: 119 AEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDVMSDVNNVLAQMKD 178

Query: 180 FSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTH 239
           F+E+VR+GEWKG TGK+I ++VNIGIGGSDLGPVM TEALKPFS+RDL   FVSNVDGTH
Sbjct: 179 FTERVRSGEWKGQTGKSIYNIVNIGIGGSDLGPVMVTEALKPFSKRDLHCFFVSNVDGTH 238

Query: 240 IAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVAL 299
           +AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+ YL+  GI   G+VAKHFVAL
Sbjct: 239 MAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMSYLKENGISTDGAVAKHFVAL 298

Query: 300 STNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEH 359
           STN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NFVE LTGAHV+D H
Sbjct: 299 STNTEKVREFGIDTVNMFAFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNH 358

Query: 360 FANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTR 419
           FA+ P EQN+P++LALVG+WY NFFG+ T A+LPYDQYLWRLPAYLQQLDMESNGK VT+
Sbjct: 359 FASTPTEQNLPMMLALVGIWYNNFFGSETQAVLPYDQYLWRLPAYLQQLDMESNGKGVTK 418

Query: 420 SGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSN 479
               V+  TGPI+FGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+QN++GDHH+  MSN
Sbjct: 419 KSGAVAVQTGPIVFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRTLMSN 478

Query: 480 FFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRAL 539
           FFAQTEALM+GK+  EVR+EL  +G  S + I  ++PHKTF G RPSN++L+ +LTPRAL
Sbjct: 479 FFAQTEALMVGKNAEEVRQELVKSG-MSGDAIENMIPHKTFTGSRPSNSILVNALTPRAL 537

Query: 540 GAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLIN 599
           GAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  V++HD STNGLIN
Sbjct: 538 GAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLIN 597

Query: 600 MFNELSHL 607
           MFN  +HL
Sbjct: 598 MFNTRAHL 605
>gb|ABU25165.1| glucose-6-phosphate isomerase [Leishmania braziliensis]
          Length = 581

 Score =  875 bits (2260), Expect = 0.0,   Method: Composition-based stats.
 Identities = 406/584 (69%), Positives = 493/584 (84%), Gaps = 3/584 (0%)

Query: 24  IAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQ 83
           +A  +FN PYE+ R+ K +GA +D++L+  ++W +L+ LYE+YG E I  HFE D +R  
Sbjct: 1   MATATFNAPYEIARKTKALGA-SDSSLSKLSAWKRLEFLYEKYGSESILSHFEKDQQRFS 59

Query: 84  RYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTEN 143
           RYS++V L   D+NFLFLDYSKSHINDE+K AL+ LAEERG+R F++++F G++VN+TE 
Sbjct: 60  RYSIEVPLQC-DDNFLFLDYSKSHINDEVKDALVALAEERGVRAFIKAMFDGQQVNSTEK 118

Query: 144 RPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNI 203
           R VLH+ALRNRSNR I V+GKD+M  VN VL QM+ F++KVR+GEWKG TGK+I ++VN+
Sbjct: 119 RAVLHVALRNRSNRAINVNGKDIMTDVNLVLAQMKDFTDKVRSGEWKGQTGKSIHYIVNV 178

Query: 204 GIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTT 263
           GIGGSDLGPVM  E+LKPFS RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTT
Sbjct: 179 GIGGSDLGPVMVYESLKPFSMRDMHCFFVSNVDGTHMAEVLKQVNMEETIFIIASKTFTT 238

Query: 264 QETITNALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWV 323
           QET+TNA+SAR A +DYL+S  I   G+VAKHFVA+STN ++V+EFGID  NMF+FWDWV
Sbjct: 239 QETLTNAMSARNAFIDYLKSNNIPSDGAVAKHFVAISTNAKEVREFGIDTANMFEFWDWV 298

Query: 324 GGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINF 383
           GGRYS+WSAIGL +M+SIGYENFVE LTGAHVID HFA+AP EQN+P++LALVG+WY NF
Sbjct: 299 GGRYSVWSAIGLSVMLSIGYENFVEFLTGAHVIDNHFASAPVEQNLPMMLALVGIWYNNF 358

Query: 384 FGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHA 443
           FGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHA
Sbjct: 359 FGAETQAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVTVQTGPIIFGEAGTNGQHA 418

Query: 444 FYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAA 503
           FYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +
Sbjct: 419 FYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELVKS 478

Query: 504 GERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           G  S + I +LLPHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 479 GMPS-DAIESLLPHKTFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYD 537

Query: 564 QWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           QWGVELGKVLAKSILPQL+ G  V+NHD STNGLINMFN  +HL
Sbjct: 538 QWGVELGKVLAKSILPQLKSGNIVSNHDGSTNGLINMFNTRAHL 581
>ref|XP_001563099.1| glucose-6-phosphate isomerase [Leishmania braziliensis
           MHOM/BR/75/M2904]
 emb|CAM37422.1| glucose-6-phosphate isomerase [Leishmania braziliensis]
 gb|ABU25162.1| glucose-6-phosphate isomerase [Leishmania braziliensis]
 gb|ABU25163.1| glucose-6-phosphate isomerase [Leishmania braziliensis]
 gb|ABU25164.1| glucose-6-phosphate isomerase [Leishmania peruviana]
          Length = 581

 Score =  874 bits (2259), Expect = 0.0,   Method: Composition-based stats.
 Identities = 406/584 (69%), Positives = 494/584 (84%), Gaps = 3/584 (0%)

Query: 24  IAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQ 83
           +A  +FN PYE+ R+ K +GA +D++L+  ++W +L+ LYE+YG+E I  HFE D +R  
Sbjct: 1   MATATFNAPYEIARKTKVLGA-SDSSLSKLSAWKRLEFLYEKYGNESILSHFEKDQQRFS 59

Query: 84  RYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTEN 143
           RYS++V L   D+NFLFLDYSKSHINDE+K AL+ LAEERG+R F++++F G++VN+TE 
Sbjct: 60  RYSIEVPLQC-DDNFLFLDYSKSHINDEVKDALVALAEERGVRAFIKAMFDGQQVNSTEK 118

Query: 144 RPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNI 203
           R VLH+ALRNRSNR I V+GKD+M  VN VL QM+ F++KVR+GEWKG TGK+I ++VN+
Sbjct: 119 RAVLHVALRNRSNRAINVNGKDIMTDVNLVLAQMKDFTDKVRSGEWKGQTGKSIHYIVNV 178

Query: 204 GIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTT 263
           GIGGSDLGPVM  E+LKPFS RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTT
Sbjct: 179 GIGGSDLGPVMVYESLKPFSMRDMHCFFVSNVDGTHMAEVLKQVNMEETIFIIASKTFTT 238

Query: 264 QETITNALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWV 323
           QET+TNA+SAR A +DYL+S  I   G+VAKHFVA+STN ++V+EFGID  NMF+FWDWV
Sbjct: 239 QETLTNAMSARNAFIDYLKSNNIPSDGAVAKHFVAISTNAKEVREFGIDTANMFEFWDWV 298

Query: 324 GGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINF 383
           GGRYS+WSAIGL +M+SIGYENFVE LTGAHVID HFA+AP EQN+P++LALVG+WY NF
Sbjct: 299 GGRYSVWSAIGLSVMLSIGYENFVEFLTGAHVIDNHFASAPVEQNLPMMLALVGIWYNNF 358

Query: 384 FGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHA 443
           FGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHA
Sbjct: 359 FGAETQAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVTVQTGPIIFGEAGTNGQHA 418

Query: 444 FYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAA 503
           FYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +
Sbjct: 419 FYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELVKS 478

Query: 504 GERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           G  S + I +LLPHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 479 GMPS-DAIESLLPHKTFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYD 537

Query: 564 QWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           QWGVELGKVLAKSILPQL+ G  V+NHD STNGLINMFN  +HL
Sbjct: 538 QWGVELGKVLAKSILPQLKSGNIVSNHDGSTNGLINMFNTRAHL 581
>gb|ABU25168.1| glucose-6-phosphate isomerase [Leishmania lainsoni]
          Length = 581

 Score =  874 bits (2258), Expect = 0.0,   Method: Composition-based stats.
 Identities = 409/584 (70%), Positives = 490/584 (83%), Gaps = 3/584 (0%)

Query: 24  IAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQ 83
           +A  +FN PYE+ R+ K +G  +D++L    +W +LQ LYE+YG E I  HFE D +R  
Sbjct: 1   MATATFNAPYEIARKTKVLGT-SDSSLLKLPAWKRLQFLYEKYGSESIFSHFEKDQQRFS 59

Query: 84  RYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTEN 143
           RYS++V L   D+NFLFLDYSKSHINDE+K AL+ LAEERG+R F++++F G++VN+TEN
Sbjct: 60  RYSIEVPL-QGDDNFLFLDYSKSHINDEVKDALVALAEERGVRAFIKAMFDGQQVNSTEN 118

Query: 144 RPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNI 203
           R VLH+ALRNRSNR I V+GKD+M  VN VL QM+ F++KVR+GEWKG TGK+I ++VN+
Sbjct: 119 RAVLHVALRNRSNRVINVNGKDIMADVNLVLAQMKDFTDKVRSGEWKGQTGKSIHYIVNV 178

Query: 204 GIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTT 263
           GIGGSDLGPVM  EALKPFS RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTT
Sbjct: 179 GIGGSDLGPVMVYEALKPFSMRDMHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTT 238

Query: 264 QETITNALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWV 323
           QET+TNA+SAR AL+DYL+S  I   G+VAKHFVALSTN ++V+EFGID  NMF+FWDWV
Sbjct: 239 QETLTNAMSARNALMDYLKSNSISSDGAVAKHFVALSTNAKEVREFGIDTANMFEFWDWV 298

Query: 324 GGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINF 383
           GGRYS+WSAIGL +M+SIGYENFVE LTGAHVID HFA+AP EQN+P++LALVG+WY NF
Sbjct: 299 GGRYSVWSAIGLSVMLSIGYENFVEFLTGAHVIDNHFASAPVEQNLPMMLALVGIWYNNF 358

Query: 384 FGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHA 443
           FGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHA
Sbjct: 359 FGAETQAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVTVQTGPIIFGEAGTNGQHA 418

Query: 444 FYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAA 503
           FYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +
Sbjct: 419 FYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELVKS 478

Query: 504 GERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           G  S + I  LLPHK F G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 479 GMPS-DAIETLLPHKMFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYD 537

Query: 564 QWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           QWGVELGKVLAKSILPQL+ G  V+NHD STNGLINMFN  +HL
Sbjct: 538 QWGVELGKVLAKSILPQLKSGNIVSNHDGSTNGLINMFNTRAHL 581
>gb|ABU25166.1| glucose-6-phosphate isomerase [Leishmania guyanensis]
 gb|ABU25167.1| glucose-6-phosphate isomerase [Leishmania panamensis]
          Length = 581

 Score =  873 bits (2255), Expect = 0.0,   Method: Composition-based stats.
 Identities = 405/584 (69%), Positives = 492/584 (84%), Gaps = 3/584 (0%)

Query: 24  IAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQ 83
           +A  +FN PYE+ R+ K +GA +D++L+  ++W +L+ LYE+YG E I  HFE D +R  
Sbjct: 1   MATATFNAPYEIARKTKVLGA-SDSSLSKLSAWKRLEFLYEKYGSESILSHFEKDQQRFS 59

Query: 84  RYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTEN 143
           RYS++V L   D+NFLFLDYSKSHINDE+K AL+ LAEERG+R F++++F G++VN+TE 
Sbjct: 60  RYSIEVPLQC-DDNFLFLDYSKSHINDEVKDALVALAEERGVRAFIKAMFDGQQVNSTEK 118

Query: 144 RPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNI 203
           R VLH+ALRNRSNR I V+GKD+M  VN VL QM+ F+++VR+GEWKG TGK+I ++VN+
Sbjct: 119 RAVLHVALRNRSNRAINVNGKDIMTDVNLVLSQMKDFTDRVRSGEWKGQTGKSIHYIVNV 178

Query: 204 GIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTT 263
           GIGGSDLGPVM  E+LKPFS RD+   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTT
Sbjct: 179 GIGGSDLGPVMVYESLKPFSMRDMHCFFVSNVDGTHMAEVLKQVNMEETIFIIASKTFTT 238

Query: 264 QETITNALSARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWV 323
           QET+TNA+SAR A +DYL+S  I   G+VAKHFVALSTN ++V+EFGID  NMF+FWDWV
Sbjct: 239 QETLTNAMSARNAFMDYLKSNNIPSDGAVAKHFVALSTNAKEVREFGIDTANMFEFWDWV 298

Query: 324 GGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINF 383
           GGRYS+WSAIGL +M+SIGYENFVE LTGAHVID HF +AP EQN+P++LALVG+WY NF
Sbjct: 299 GGRYSVWSAIGLSVMLSIGYENFVEFLTGAHVIDNHFVSAPVEQNLPMMLALVGIWYNNF 358

Query: 384 FGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHA 443
           FGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+    V+  TGPIIFGEAGTNGQHA
Sbjct: 359 FGAETQAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVTVQTGPIIFGEAGTNGQHA 418

Query: 444 FYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAA 503
           FYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSNFFAQTEALM+GKS  EVR+EL  +
Sbjct: 419 FYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFFAQTEALMVGKSAEEVRQELVKS 478

Query: 504 GERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           G  S + I +LLPHKTF G RPSN++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 479 GMPS-DAIESLLPHKTFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYD 537

Query: 564 QWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNELSHL 607
           QWGVELGKVLAKSILPQL+ G  V+NHD STNGLINMFN  +HL
Sbjct: 538 QWGVELGKVLAKSILPQLKSGNIVSNHDGSTNGLINMFNTRAHL 581
>pdb|1Q50|A Chain A, Phosphoglucose Isomerase From Leishmania Mexicana.
          Length = 561

 Score =  860 bits (2222), Expect = 0.0,   Method: Composition-based stats.
 Identities = 398/560 (71%), Positives = 477/560 (85%), Gaps = 2/560 (0%)

Query: 47  DTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
           D++L +  +W +LQ LYE+YG++ I  HFE D +R QRYS+++ L S D+NFLFLDYSKS
Sbjct: 4   DSSLLNLPAWKRLQSLYEKYGNDSILSHFEKDHQRFQRYSIEIDLHS-DDNFLFLDYSKS 62

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
           HINDEIK AL+ LAEERG+R F +++F G+RVN+TENR VLH+ALRNRSNRPI VDGKDV
Sbjct: 63  HINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDV 122

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           M  VN VL QM+ F+E+VR+GEWKG TGK+I ++VNIGIGGSDLGPVM TEALKPFS+RD
Sbjct: 123 MSDVNNVLAQMKDFTERVRSGEWKGQTGKSIYNIVNIGIGGSDLGPVMVTEALKPFSKRD 182

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
           L   FVSNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+ YL+  GI
Sbjct: 183 LHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMSYLKENGI 242

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
              G+VAKHFVALSTN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NF
Sbjct: 243 STDGAVAKHFVALSTNTEKVREFGIDTVNMFAFWDWVGGRYSVWSAIGLSVMLSIGYDNF 302

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
           VE LTGAHV+D HFA+ P EQN+P++LALVG+WY NFFG+ T A+LPYDQYLWRLPAYLQ
Sbjct: 303 VEFLTGAHVMDNHFASTPTEQNLPMMLALVGIWYNNFFGSETQAVLPYDQYLWRLPAYLQ 362

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           QLDMESNGK VT+    V+  TGPI+FGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+Q
Sbjct: 363 QLDMESNGKGVTKKSGAVAVQTGPIVFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQ 422

Query: 467 NKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           N++GDHH+  MSNFFAQTEALM+GK+  EVR+EL  +G  S + I  ++PHKTF G RPS
Sbjct: 423 NRVGDHHRTLMSNFFAQTEALMVGKNAEEVRQELVKSG-MSGDAIENMIPHKTFTGSRPS 481

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N++L+ +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  
Sbjct: 482 NSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNI 541

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V++HD STNGLINMFN  +H
Sbjct: 542 VSDHDGSTNGLINMFNTRAH 561
>gb|AAR89408.1| glucose-6-phosphate isomerase [Trypanosoma brucei gambiense]
          Length = 411

 Score =  854 bits (2207), Expect = 0.0,   Method: Composition-based stats.
 Identities = 410/411 (99%), Positives = 410/411 (99%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP
Sbjct: 1   NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS
Sbjct: 61  VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA
Sbjct: 121 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL
Sbjct: 181 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
           NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN
Sbjct: 301 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           ALLPHK FIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD
Sbjct: 361 ALLPHKXFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 411
>gb|AAR89410.1| glucose-6-phosphate isomerase [Trypanosoma brucei brucei]
          Length = 411

 Score =  847 bits (2189), Expect = 0.0,   Method: Composition-based stats.
 Identities = 407/411 (99%), Positives = 407/411 (99%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTG A  HVVNIGIGGSDLGP
Sbjct: 1   NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGNAXXHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS
Sbjct: 61  VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA
Sbjct: 121 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL
Sbjct: 181 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
           NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN
Sbjct: 301 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           ALLPHK FIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD
Sbjct: 361 ALLPHKXFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 411
>gb|AAR89411.1| glucose-6-phosphate isomerase [Trypanosoma brucei rhodesiense]
          Length = 412

 Score =  846 bits (2186), Expect = 0.0,   Method: Composition-based stats.
 Identities = 407/412 (98%), Positives = 407/412 (98%)

Query: 152 RNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLG 211
           RNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKV T EWKGHTGKA  HVVNIGIGGSDLG
Sbjct: 1   RNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVXTXEWKGHTGKAXXHVVNIGIGGSDLG 60

Query: 212 PVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNAL 271
           PVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNAL
Sbjct: 61  PVMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNAL 120

Query: 272 SARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWS 331
           SARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWS
Sbjct: 121 SARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWS 180

Query: 332 AIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAI 391
           AIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAI
Sbjct: 181 AIGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAI 240

Query: 392 LPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQG 451
           LPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQG
Sbjct: 241 LPYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQG 300

Query: 452 TNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKI 511
           TNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKI
Sbjct: 301 TNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKI 360

Query: 512 NALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           NALLPHK FIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD
Sbjct: 361 NALLPHKXFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 412
>gb|AAR89409.1| glucose-6-phosphate isomerase [Trypanosoma brucei gambiense]
          Length = 406

 Score =  846 bits (2185), Expect = 0.0,   Method: Composition-based stats.
 Identities = 406/406 (100%), Positives = 406/406 (100%)

Query: 157 RPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMAT 216
           RPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMAT
Sbjct: 1   RPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMAT 60

Query: 217 EALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRA 276
           EALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRA
Sbjct: 61  EALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRA 120

Query: 277 LLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLP 336
           LLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLP
Sbjct: 121 LLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLP 180

Query: 337 IMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQ 396
           IMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQ
Sbjct: 181 IMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQ 240

Query: 397 YLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIP 456
           YLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIP
Sbjct: 241 YLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIP 300

Query: 457 CDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLP 516
           CDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLP
Sbjct: 301 CDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLP 360

Query: 517 HKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSY 562
           HKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSY
Sbjct: 361 HKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSY 406
>gb|AAR89412.1| glucose-6-phosphate isomerase [Trypanosoma congolense]
          Length = 411

 Score =  793 bits (2048), Expect = 0.0,   Method: Composition-based stats.
 Identities = 373/411 (90%), Positives = 395/411 (96%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPI VDGKDVMP VNKVLDQM  FS+KVR GEWKGHTGK+IRHVVNIGIGGSDLGP
Sbjct: 1   NRSNRPILVDGKDVMPDVNKVLDQMHCFSDKVRNGEWKGHTGKSIRHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           VMATEALKPFSQR +SLHFVSNVDGTHI+EVLKSIDIEATLFIVASKTFTTQETITNALS
Sbjct: 61  VMATEALKPFSQRSISLHFVSNVDGTHISEVLKSIDIEATLFIVASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           AR ALL+YL+S+GI++ G+VA HFVALSTN +KVKEFGIDEENMFQFWDWVGGRYS+WSA
Sbjct: 121 ARNALLNYLKSQGINDDGAVAXHFVALSTNTRKVKEFGIDEENMFQFWDWVGGRYSLWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGLPIMISIGYENFVELLTGA V+DEHF N PPE+N+P+LLALVGVWYINFFGAVTHAIL
Sbjct: 181 IGLPIMISIGYENFVELLTGAFVVDEHFVNEPPERNIPMLLALVGVWYINFFGAVTHAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGK VTR+G+TVSTLTGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKCVTRNGETVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
           NLIPCDFIGAIQ+QNKIGDHHKIFMSNFFAQTEALMIGK+P EVRRELEAAGE+SA+KI 
Sbjct: 301 NLIPCDFIGAIQTQNKIGDHHKIFMSNFFAQTEALMIGKTPIEVRRELEAAGEKSADKIK 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD
Sbjct: 361 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 411
>gb|AAR89396.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 411

 Score =  706 bits (1821), Expect = 0.0,   Method: Composition-based stats.
 Identities = 325/411 (79%), Positives = 369/411 (89%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPI+VDG DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP
Sbjct: 1   NRSNRPIFVDGNDVMPLVNKVLEQMKKLSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           +MA EALKPFS R +S+HFVSN+DGTH++EVLK +D+E+TLFI+ASKTFTTQETITNALS
Sbjct: 61  MMACEALKPFSDRKISMHFVSNIDGTHLSEVLKLVDLESTLFIIASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           AR   L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSA
Sbjct: 121 ARSEFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEANMFQFWDWVGGRYSLWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGL +MISIGY+NFVE LTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AIL
Sbjct: 181 IGLSVMISIGYDNFVEFLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
            LIPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I 
Sbjct: 301 KLIPCDFIGAIQTQNHIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQ 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
            L+P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 361 LLIPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYD 411
>gb|AAR89394.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 411

 Score =  704 bits (1818), Expect = 0.0,   Method: Composition-based stats.
 Identities = 324/411 (78%), Positives = 369/411 (89%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPI+V+G DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP
Sbjct: 1   NRSNRPIFVNGNDVMPLVNKVLEQMKKLSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           +MA EALKPFS R +S+HFVSN+DGTH++EVLK +D+E+TLFI+ASKTFTTQETITNALS
Sbjct: 61  MMACEALKPFSDRRISMHFVSNIDGTHLSEVLKLVDLESTLFIIASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           AR   L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSA
Sbjct: 121 ARSEFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEANMFQFWDWVGGRYSLWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGL +MISIGY+NFVE LTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AIL
Sbjct: 181 IGLSVMISIGYDNFVEFLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
            LIPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I 
Sbjct: 301 KLIPCDFIGAIQTQNCIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQ 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
            L+P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 361 LLIPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYD 411
>gb|AAR89398.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 411

 Score =  704 bits (1816), Expect = 0.0,   Method: Composition-based stats.
 Identities = 324/411 (78%), Positives = 370/411 (90%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPI+V+G DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP
Sbjct: 1   NRSNRPIFVNGHDVMPLVNKVLEQMKKLSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           +MA EAL+PFS R +S+HFVSN+DGTH++EVL  +D+E+TLFI+ASKTFTTQETITNALS
Sbjct: 61  MMACEALRPFSDRRISMHFVSNIDGTHLSEVLNLVDLESTLFIIASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           AR   L +L SRGI E G+VAKHFVALSTN +KVKEFGIDEENMFQFWDWVGGRYS+WSA
Sbjct: 121 ARNEFLKFLSSRGISEAGAVAKHFVALSTNAEKVKEFGIDEENMFQFWDWVGGRYSLWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGL +MISIGY+NFVELLTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AIL
Sbjct: 181 IGLSVMISIGYDNFVELLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
            LIPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I 
Sbjct: 301 KLIPCDFIGAIQTQNYIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQ 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
            L+P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 361 LLIPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYD 411
>gb|AAR89407.1| glucose-6-phosphate isomerase [Trypanosoma rangeli]
          Length = 411

 Score =  704 bits (1816), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/410 (78%), Positives = 370/410 (90%)

Query: 154 RSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPV 213
           RSNRPI+V G DVMP VN+VL+QMR  SEKVR G+WKG +GK IRHVVNIGIGGSDLGP+
Sbjct: 2   RSNRPIFVHGHDVMPLVNQVLEQMRRMSEKVRNGDWKGQSGKTIRHVVNIGIGGSDLGPM 61

Query: 214 MATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSA 273
           MA EALKPFS R++S+HFVSN+DGTH++EVLK +D+EATLFI+ASKTFTTQETITNALSA
Sbjct: 62  MACEALKPFSDRNISMHFVSNIDGTHLSEVLKLVDLEATLFIIASKTFTTQETITNALSA 121

Query: 274 RRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAI 333
           R   L +LRSRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSAI
Sbjct: 122 RNEFLKFLRSRGISEVGAVAKHFVALSTNAEKVKEFGIDEANMFQFWDWVGGRYSLWSAI 181

Query: 334 GLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILP 393
           GL +MISIGY+NFVELLTGAH++DEHF NAP E N+P++LALVG+WY NFFG  THAILP
Sbjct: 182 GLSLMISIGYDNFVELLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGTETHAILP 241

Query: 394 YDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTN 453
           YDQYLWRLPAYLQQLDMESNGK  T++G+ V+T TGPIIFGEAGTNG HAFYQLIHQGT 
Sbjct: 242 YDQYLWRLPAYLQQLDMESNGKGATKNGRMVTTHTGPIIFGEAGTNGPHAFYQLIHQGTK 301

Query: 454 LIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINA 513
           L+PCDFIGAIQ+QN+IGDHH+I MSNFFAQTEALM+GK+P EV++E++ AG +S  +I +
Sbjct: 302 LVPCDFIGAIQTQNRIGDHHRILMSNFFAQTEALMLGKTPGEVQQEMKTAGGKSEREICS 361

Query: 514 LLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           LLPHKTF GGRPSN+LL+K++TPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 362 LLPHKTFTGGRPSNSLLVKAITPRALGAIIAMYEHKVLVQGAIWGINSYD 411
>gb|AAR89403.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 411

 Score =  702 bits (1812), Expect = 0.0,   Method: Composition-based stats.
 Identities = 324/411 (78%), Positives = 368/411 (89%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPI+VDG DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP
Sbjct: 1   NRSNRPIFVDGHDVMPXVNKVLEQMKKXSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           +MA EALKPFS R +S+HFVSN+DGTH++EVL  +D+E+TLFI+ASKTFTTQETITNALS
Sbjct: 61  MMACEALKPFSDRRISMHFVSNIDGTHLSEVLXLVDLESTLFIIASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           AR   L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSA
Sbjct: 121 ARXXFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEANMFQFWDWVGGRYSLWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGL +MISIGY+NFVE LTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AIL
Sbjct: 181 IGLSVMISIGYDNFVEFLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
            LIPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I 
Sbjct: 301 KLIPCDFIGAIQTQNYIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQ 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
            L+P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 361 LLIPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYD 411
>gb|AAR89397.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 411

 Score =  701 bits (1809), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/411 (78%), Positives = 369/411 (89%)

Query: 153 NRSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGP 212
           NRSNRPI+V+G DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP
Sbjct: 1   NRSNRPIFVNGHDVMPLVNKVLEQMKKLSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGP 60

Query: 213 VMATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALS 272
           +MA EAL+PFS R +S+HFVSN+DGTH++EVL  +D+E+TLFI+ASKTFTTQETITNALS
Sbjct: 61  MMACEALRPFSDRRISMHFVSNIDGTHLSEVLNLVDLESTLFIIASKTFTTQETITNALS 120

Query: 273 ARRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSA 332
           AR   L +L SRGI E G+VAKHFVALSTN +KVKEFGIDEENMFQFWDWVGGRYS+WSA
Sbjct: 121 ARNEFLKFLSSRGISEAGAVAKHFVALSTNAEKVKEFGIDEENMFQFWDWVGGRYSLWSA 180

Query: 333 IGLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAIL 392
           IGL +MISIGY+NFVELLTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AIL
Sbjct: 181 IGLSVMISIGYDNFVELLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAIL 240

Query: 393 PYDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGT 452
           PYDQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT
Sbjct: 241 PYDQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGT 300

Query: 453 NLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKIN 512
            LIPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I 
Sbjct: 301 KLIPCDFIGAIQTQNYIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQ 360

Query: 513 ALLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
            L+P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLV GAIWGI+SYD
Sbjct: 361 LLIPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVLGAIWGINSYD 411
>emb|CAH90643.1| glucose-6-phosphate isomerase [Leishmania sp. MHOM/IN/2003/NAV-135]
          Length = 435

 Score =  700 bits (1807), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/435 (74%), Positives = 378/435 (86%), Gaps = 1/435 (0%)

Query: 173 VLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFV 232
           VL QM+ F EKVR+ EWKG TGK+I ++VNIGIGGSDLGPVM TEALKPFS+RD+   FV
Sbjct: 2   VLAQMKDFXEKVRSXEWKGQTGKSISNIVNIGIGGSDLGPVMVTEALKPFSKRDMHCFFV 61

Query: 233 SNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSV 292
           SNVDGTH+AEVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+DYL++  I   G+V
Sbjct: 62  SNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMDYLKANNISTDGAV 121

Query: 293 AKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTG 352
           AKHFVALSTN +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NFVE LTG
Sbjct: 122 AKHFVALSTNTEKVREFGIDTVNMFVFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTG 181

Query: 353 AHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMES 412
           AHV+D HFA+AP EQN+P++LALVG+WY NFFGA T A+LPYDQYLWRLPAYLQQLDMES
Sbjct: 182 AHVMDNHFASAPTEQNLPMMLALVGIWYNNFFGAETEAVLPYDQYLWRLPAYLQQLDMES 241

Query: 413 NGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDH 472
           NGK VT+    V+  TGPIIFGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+QN++GDH
Sbjct: 242 NGKGVTKKSGAVAVQTGPIIFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDH 301

Query: 473 HKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIK 532
           H+I MSNFFAQTEALM+GKS  EVR+EL  +G  S E I +++PHKTF G RPSN++L+ 
Sbjct: 302 HRILMSNFFAQTEALMVGKSAEEVRQELAKSG-MSDEAIQSMIPHKTFTGNRPSNSILVN 360

Query: 533 SLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDS 592
           +LTPRALGAIIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  V++HD 
Sbjct: 361 ALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDG 420

Query: 593 STNGLINMFNELSHL 607
           STNGLINMFN  +HL
Sbjct: 421 STNGLINMFNTRAHL 435
>gb|AAR89406.1| glucose-6-phosphate isomerase [Trypanosoma cruzi marinkellei]
          Length = 409

 Score =  700 bits (1806), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/409 (78%), Positives = 367/409 (89%)

Query: 155 SNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVM 214
           SNRPI+V+G DVMP VN+VL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP+M
Sbjct: 1   SNRPIFVNGHDVMPLVNRVLEQMKELSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGPMM 60

Query: 215 ATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSAR 274
           A EALKPFS R +S+HFVSN+DGTH++EVLK +D+E+TLFI+ASKTFTTQETITNALSAR
Sbjct: 61  ACEALKPFSDRRISMHFVSNIDGTHLSEVLKLVDLESTLFIIASKTFTTQETITNALSAR 120

Query: 275 RALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIG 334
            A L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSAIG
Sbjct: 121 NAFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEANMFQFWDWVGGRYSLWSAIG 180

Query: 335 LPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPY 394
           L +MISIGY NFVELLTGAH++DEHF NAP E NVP++LALVG+WY NFFG+ T AILPY
Sbjct: 181 LSVMISIGYNNFVELLTGAHIMDEHFINAPTENNVPIILALVGIWYNNFFGSETQAILPY 240

Query: 395 DQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNL 454
           DQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT L
Sbjct: 241 DQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGTKL 300

Query: 455 IPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINAL 514
           IPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I  L
Sbjct: 301 IPCDFIGAIQTQNCIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQLL 360

Query: 515 LPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           +P K F GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 361 VPQKAFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYD 409
>gb|AAR89399.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 408

 Score =  699 bits (1803), Expect = 0.0,   Method: Composition-based stats.
 Identities = 322/408 (78%), Positives = 366/408 (89%)

Query: 156 NRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMA 215
           NRPI+VDG DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP+MA
Sbjct: 1   NRPIFVDGHDVMPLVNKVLEQMKKLSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGPMMA 60

Query: 216 TEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARR 275
            EALKPFS R +S+HFVSN+DGTH++EVLK +D+E+TLFI+ASKTFTTQETITNALSAR 
Sbjct: 61  CEALKPFSDRRISMHFVSNIDGTHLSEVLKLVDLESTLFIIASKTFTTQETITNALSARS 120

Query: 276 ALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGL 335
             L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSAIGL
Sbjct: 121 EFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEANMFQFWDWVGGRYSLWSAIGL 180

Query: 336 PIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYD 395
            +MISIGY+NFVE LTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AILPYD
Sbjct: 181 SVMISIGYDNFVEFLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAILPYD 240

Query: 396 QYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLI 455
           QYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT LI
Sbjct: 241 QYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGTKLI 300

Query: 456 PCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALL 515
           PCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I  L+
Sbjct: 301 PCDFIGAIQTQNYIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQLLI 360

Query: 516 PHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 361 PQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYD 408
>gb|AAR89405.1| glucose-6-phosphate isomerase [Trypanosoma cruzi marinkellei]
          Length = 409

 Score =  697 bits (1800), Expect = 0.0,   Method: Composition-based stats.
 Identities = 322/409 (78%), Positives = 366/409 (89%)

Query: 155 SNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVM 214
           SNRPI+V+G DVMP VN+VL+QM+  SEKVR GEWKG +GK  RHVVNIGIGGSDLGP+M
Sbjct: 1   SNRPIFVNGHDVMPLVNRVLEQMKELSEKVRRGEWKGQSGKPXRHVVNIGIGGSDLGPMM 60

Query: 215 ATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSAR 274
           A EALKPFS R +S+HFVSN+DGTH++EVLK +D+E+TLFI+ASKTFTTQETITNALSAR
Sbjct: 61  ACEALKPFSDRRISMHFVSNIDGTHLSEVLKLVDLESTLFIIASKTFTTQETITNALSAR 120

Query: 275 RALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIG 334
            A L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSAIG
Sbjct: 121 NAFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEANMFQFWDWVGGRYSLWSAIG 180

Query: 335 LPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPY 394
           L +MISIGY NFVELLTGAH++DEHF NAP E NVP++LALVG+WY NFFG+ T AILPY
Sbjct: 181 LSVMISIGYNNFVELLTGAHIMDEHFINAPTENNVPIILALVGIWYNNFFGSETQAILPY 240

Query: 395 DQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNL 454
           DQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT L
Sbjct: 241 DQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGTKL 300

Query: 455 IPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINAL 514
           IPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I  L
Sbjct: 301 IPCDFIGAIQTQNCIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQLL 360

Query: 515 LPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           +P K F GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 361 VPQKAFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYD 409
>gb|AAR89402.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 409

 Score =  695 bits (1793), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/409 (78%), Positives = 365/409 (89%)

Query: 155 SNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVM 214
           SNRPI+VDG DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP+M
Sbjct: 1   SNRPIFVDGHDVMPXVNKVLEQMKKXSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGPMM 60

Query: 215 ATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSAR 274
           A EAL PFS R +S+HFVSN+DGTH++EVL  +D+E+TLFI+ASKTFTTQETITNALSAR
Sbjct: 61  ACEALXPFSDRRISMHFVSNIDGTHLSEVLXLVDLESTLFIIASKTFTTQETITNALSAR 120

Query: 275 RALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIG 334
              L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSAIG
Sbjct: 121 XXFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEXNMFQFWDWVGGRYSLWSAIG 180

Query: 335 LPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPY 394
           L +MISIGY+NFVE LTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AILPY
Sbjct: 181 LSVMISIGYDNFVEXLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAILPY 240

Query: 395 DQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNL 454
           DQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT L
Sbjct: 241 DQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGTKL 300

Query: 455 IPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINAL 514
           IPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I  L
Sbjct: 301 IPCDFIGAIQTQNYIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQLL 360

Query: 515 LPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           +P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 361 IPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYD 409
>gb|AAR89401.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 409

 Score =  695 bits (1793), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/409 (78%), Positives = 365/409 (89%)

Query: 154 RSNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPV 213
           RSNRPI+VDG DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP+
Sbjct: 1   RSNRPIFVDGHDVMPXVNKVLEQMKKXSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGPM 60

Query: 214 MATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSA 273
           MA EAL PFS R +S+HFVSN+DGTH++EVL  +D+E+TLFI+ASKTFTTQETITNALSA
Sbjct: 61  MACEALXPFSDRRISMHFVSNIDGTHLSEVLXLVDLESTLFIIASKTFTTQETITNALSA 120

Query: 274 RRALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAI 333
           R   L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSAI
Sbjct: 121 RXXFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEXNMFQFWDWVGGRYSLWSAI 180

Query: 334 GLPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILP 393
           GL +MISIGY+NFVE LTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AILP
Sbjct: 181 GLSVMISIGYDNFVEXLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAILP 240

Query: 394 YDQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTN 453
           YDQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT 
Sbjct: 241 YDQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGTK 300

Query: 454 LIPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINA 513
           LIPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I  
Sbjct: 301 LIPCDFIGAIQTQNYIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQL 360

Query: 514 LLPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSY 562
           L+P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SY
Sbjct: 361 LIPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSY 409
>gb|AAR89400.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 407

 Score =  694 bits (1792), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/407 (78%), Positives = 364/407 (89%)

Query: 156 NRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMA 215
           NRPI+VDG DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP+MA
Sbjct: 1   NRPIFVDGHDVMPMVNKVLEQMKKISEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGPMMA 60

Query: 216 TEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARR 275
            EALKPFS R +S+HFVSN+DGTH++EVLK +D+E+TLFI+ASKTFTTQETITNALSAR 
Sbjct: 61  CEALKPFSDRRISMHFVSNIDGTHLSEVLKLVDLESTLFIIASKTFTTQETITNALSARS 120

Query: 276 ALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGL 335
             L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSAIGL
Sbjct: 121 EFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEANMFQFWDWVGGRYSLWSAIGL 180

Query: 336 PIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYD 395
            +MISIGY+NFVE LTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AILPYD
Sbjct: 181 SVMISIGYDNFVEFLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAILPYD 240

Query: 396 QYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLI 455
           QYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGE GTNGQHAFYQLIHQGT LI
Sbjct: 241 QYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEXGTNGQHAFYQLIHQGTKLI 300

Query: 456 PCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALL 515
           PCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I  L+
Sbjct: 301 PCDFIGAIQTQNYIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQLLI 360

Query: 516 PHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSY 562
           P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SY
Sbjct: 361 PQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSY 407
>gb|AAR89404.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 409

 Score =  694 bits (1792), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/409 (78%), Positives = 365/409 (89%)

Query: 155 SNRPIYVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVM 214
           SNRPI+VBG DVMP VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP+M
Sbjct: 1   SNRPIFVBGHDVMPXVNKVLEQMKKXSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGPMM 60

Query: 215 ATEALKPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSAR 274
           A EAL PFS R +S+HFVSN+DGTH++EVL  +D+E+TLFI+ASKTFTTQETITNALSAR
Sbjct: 61  ACEALXPFSDRRISMHFVSNIDGTHLSEVLXLVDLESTLFIIASKTFTTQETITNALSAR 120

Query: 275 RALLDYLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIG 334
              L +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSAIG
Sbjct: 121 XXFLKFLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEXNMFQFWDWVGGRYSLWSAIG 180

Query: 335 LPIMISIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPY 394
           L +MISIGY+NFVE LTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AILPY
Sbjct: 181 LSVMISIGYDNFVEXLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAILPY 240

Query: 395 DQYLWRLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNL 454
           DQYLWRLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT L
Sbjct: 241 DQYLWRLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGTKL 300

Query: 455 IPCDFIGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINAL 514
           IPCDFIGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I  L
Sbjct: 301 IPCDFIGAIQTQNYIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQLL 360

Query: 515 LPHKTFIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYD 563
           +P KTF GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAIWGI+SYD
Sbjct: 361 IPQKTFTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAIWGINSYD 409
>emb|CAH90641.2| glucose-6-phosphate isomerase [Leishmania sp. MHOM/IN/2003/NAV-122]
          Length = 425

 Score =  689 bits (1777), Expect = 0.0,   Method: Composition-based stats.
 Identities = 317/425 (74%), Positives = 371/425 (87%), Gaps = 1/425 (0%)

Query: 182 EKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHIA 241
           EKVR+GEWKG T K+I ++VNIGIGGSDLGPVM TEALKPFS+RD+   FVSNVDGTH+A
Sbjct: 1   EKVRSGEWKGQTXKSISNIVNIGIGGSDLGPVMVTEALKPFSKRDMHCFFVSNVDGTHMA 60

Query: 242 EVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALST 301
           EVLK +++E T+FI+ASKTFTTQET+TNA+SAR AL+DYL++  I   G+VAKHFVALST
Sbjct: 61  EVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMDYLKANNISTDGAVAKHFVALST 120

Query: 302 NNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHFA 361
           N +KV+EFGID  NMF FWDWVGGRYS+WSAIGL +M+SIGY+NFVE LTGAHV+D HFA
Sbjct: 121 NTEKVREFGIDTVNMFVFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNHFA 180

Query: 362 NAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRSG 421
           +AP EQN+P++LALVG+WY NFFGA T A+LPYDQYLWRLPAYLQQLDMESNGK VT+  
Sbjct: 181 SAPTEQNLPMMLALVGIWYNNFFGAETEAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKS 240

Query: 422 KTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFF 481
             V+  TGPIIFGEAGTNGQHAFYQLIHQGT +IPCDFIG +Q+QN++GDHH+I MSNFF
Sbjct: 241 GAVAVQTGPIIFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRILMSNFF 300

Query: 482 AQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALGA 541
           AQTEALM+GKS  EVR+EL  +G  S E I +++PHKTF G RPSN++L+ +LTPRALGA
Sbjct: 301 AQTEALMVGKSAEEVRQELAKSG-MSDEAIQSMIPHKTFTGNRPSNSILVNALTPRALGA 359

Query: 542 IIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINMF 601
           IIAMYEHKVLVQGAIWGI+SYDQWGVELGKVLAKSILPQL+ G  V++HD STNGLINMF
Sbjct: 360 IIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLINMF 419

Query: 602 NELSH 606
           N  +H
Sbjct: 420 NTRAH 424
>ref|YP_677101.1| glucose-6-phosphate isomerase [Cytophaga hutchinsonii ATCC 33406]
 gb|ABG57761.1| glucose-6-phosphate isomerase [Cytophaga hutchinsonii ATCC 33406]
          Length = 567

 Score =  676 bits (1744), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/554 (58%), Positives = 408/554 (73%), Gaps = 13/554 (2%)

Query: 48  TTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSH 107
           T  +   SW +L + Y +  +  ++  F AD +R  +YSV+        N + +DYSK+ 
Sbjct: 23  TNTSDFTSWKKLNEHYSKSSNLQMRDLFAADKDRFSKYSVQF-------NDILVDYSKNR 75

Query: 108 INDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVM 167
           I DE    L+ LAEE G++Q ++ +F G+++N TE R VLH+ALRNRSN PI  DGKDVM
Sbjct: 76  ITDETISLLIALAEEAGLKQAIEDMFAGKKINNTEKRSVLHVALRNRSNTPILSDGKDVM 135

Query: 168 PAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDL 227
           P VN VL++M+ F EKVR+G WKG+TGK+I  +VNIGIGGSDLGPVM TEALKP+    L
Sbjct: 136 PEVNAVLEKMKGFCEKVRSGAWKGYTGKSITDIVNIGIGGSDLGPVMVTEALKPYGSPTL 195

Query: 228 SLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGID 287
            +HFVSNVDGTHI E  K ++ E TLFI+ASKTFTTQETITNA SA+   L   +     
Sbjct: 196 HVHFVSNVDGTHIVETTKKLNPETTLFIIASKTFTTQETITNAESAKAWFLQTAK----- 250

Query: 288 EKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFV 347
           ++ +VAKHFVALSTN + V  FGID ENMF+FWDWVGGRYS+WSAIGL I + IGY+N++
Sbjct: 251 DEAAVAKHFVALSTNAKSVAAFGIDTENMFEFWDWVGGRYSLWSAIGLSIALYIGYDNYI 310

Query: 348 ELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQ 407
           ELL+GAH +D+HF   P  +N+P+LLAL+G+WY NF+ A +HAILPYDQY+ R  AY QQ
Sbjct: 311 ELLSGAHAMDKHFKETPFAKNIPVLLALIGIWYNNFYKAESHAILPYDQYMHRFAAYFQQ 370

Query: 408 LDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQN 467
            DMESNGK VT+ G  V+  TGPII+GE GTNGQHAFYQLIHQGT LIPCDF+  + SQN
Sbjct: 371 GDMESNGKRVTKDGTAVTYSTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFLAPVISQN 430

Query: 468 KIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSN 527
            IGDHH   ++NFFAQTEALM GK+ +E + ELE AG  SAE + AL+ HK F G RP+N
Sbjct: 431 PIGDHHPKLLANFFAQTEALMKGKTAAEAKAELEKAG-LSAEDVAALVNHKVFEGNRPTN 489

Query: 528 TLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRV 587
           ++  K LTP  LG++IAMYEHK+  Q  +W I+++DQWGVELGK LA +ILP+L+    V
Sbjct: 490 SIFFKKLTPFTLGSLIAMYEHKIYTQSVVWQINAFDQWGVELGKQLANAILPELKDNAAV 549

Query: 588 NNHDSSTNGLINMF 601
            +HDSSTNGLIN +
Sbjct: 550 TSHDSSTNGLINFY 563
>sp|Q4R591|G6PI_MACFA Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 dbj|BAE01734.1| unnamed protein product [Macaca fascicularis]
          Length = 558

 Score =  672 bits (1733), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/557 (57%), Positives = 418/557 (75%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGDE-PIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++G E  +++ F+AD +R   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHGSELNLRRLFDADKDRFNHFSLTLN---TNHGHILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSEGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLTQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMRGKSTDEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HD+STNGLIN   +
Sbjct: 535 VTSHDASTNGLINFIKQ 551
>ref|NP_001035561.1| glucose phosphate isomerase [Bos taurus]
 sp|Q3ZBD7|G6PI_BOVIN Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAI03417.1| Glucose phosphate isomerase [Bos taurus]
          Length = 557

 Score =  671 bits (1732), Expect = 0.0,   Method: Composition-based stats.
 Identities = 324/557 (58%), Positives = 421/557 (75%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L+  YEQ+G D  +++ FE D +R  R+S+ ++    +   + +DYSK+ +
Sbjct: 4   LTQNPQFKKLKTWYEQHGSDLNLRRLFEGDRDRFNRFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            + +   L+ +A+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TETVMQMLVDVAKSRGVEAARERMFTGEKINFTEDRAVLHVALRNRSNAPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GKAI  V+NIGIGGSDLGP+M TE+LKP+S     
Sbjct: 121 EVNRVLEKMKSFCQRVRSGEWKGYSGKAITDVINIGIGGSDLGPLMVTESLKPYSSEGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L +++ E++LFI+ASKTFTTQETITNA +A+   L  L ++   +
Sbjct: 181 VWFVSNIDGTHIAKTLATLNPESSLFIIASKTFTTQETITNAETAKEWFL--LSAK---D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V+  TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +QSQ+ 
Sbjct: 356 DMESNGKYITKSGTRVNYQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQSQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG RS E    LLPHK F G RP+
Sbjct: 416 IRNGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-RSPEDFEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 535 VTSHDSSTNGLINFIKQ 551
>pdb|1G98|A Chain A, Crystal Structure Analysis Of Rabbit Phosphoglucose
           Isomerase Complexed With 5-Phosphoarabinonate, A
           Transition State Analogue
 pdb|1G98|B Chain B, Crystal Structure Analysis Of Rabbit Phosphoglucose
           Isomerase Complexed With 5-Phosphoarabinonate, A
           Transition State Analogue
 pdb|1HOX|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Fructose-6-Phosphate
 pdb|1HOX|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Fructose-6-Phosphate
 pdb|1HM5|A Chain A, Crystal Structure Analysis Of The Rabbit D-Glucose 6-
           Phosphate Isomerase (No Ligand Bound)
 pdb|1HM5|B Chain B, Crystal Structure Analysis Of The Rabbit D-Glucose 6-
           Phosphate Isomerase (No Ligand Bound)
 pdb|1XTB|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Sorbitol-6-Phosphate
 pdb|1XTB|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Sorbitol-6-Phosphate
 gb|AAF35988.1|AF222069_1 phosphoglucose isomerase [Oryctolagus cuniculus]
          Length = 558

 Score =  671 bits (1730), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/557 (57%), Positives = 419/557 (75%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGDEPIKKH-FEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G E   +H F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L  L ++   +
Sbjct: 181 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAKTAKDWFL--LSAK---D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 535 VTSHDSSTNGLINFIKQ 551
>pdb|1DQR|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase, A
           Glycolytic Enzyme That Moonlights As Neuroleukin,
           Autocrine Motility Factor, And Differentiation Mediator
 pdb|1DQR|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase, A
           Glycolytic Enzyme That Moonlights As Neuroleukin,
           Autocrine Motility Factor, And Differentiation Mediator
 pdb|1KOJ|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With 5-Phospho-D-Arabinonohydroxamic Acid
 pdb|1KOJ|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With 5-Phospho-D-Arabinonohydroxamic Acid
          Length = 557

 Score =  671 bits (1730), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/557 (57%), Positives = 419/557 (75%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGDEPIKKH-FEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G E   +H F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 3   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 60  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 120 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L  L ++   +
Sbjct: 180 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAKTAKDWFL--LSAK---D 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 295 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 355 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 414

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 415 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 474 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 533

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 534 VTSHDSSTNGLINFIKQ 550
>ref|NP_001075538.1| phosphoglucose isomerase [Oryctolagus cuniculus]
 sp|Q9N1E2|G6PI_RABIT Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAF13713.2|AF199601_1 phosphoglucose isomerase [Oryctolagus cuniculus]
          Length = 558

 Score =  671 bits (1730), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/557 (57%), Positives = 419/557 (75%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGDEPIKKH-FEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G E   +H F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L  L ++   +
Sbjct: 181 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAETAKDWFL--LSAK---D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 535 VTSHDSSTNGLINFIKQ 551
>pdb|1N8T|A Chain A, The Crystal Structure Of Phosphoglucose Isomerase From
           Rabbit Muscle
 pdb|1N8T|B Chain B, The Crystal Structure Of Phosphoglucose Isomerase From
           Rabbit Muscle
          Length = 557

 Score =  671 bits (1730), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/557 (57%), Positives = 419/557 (75%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGDEPIKKH-FEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G E   +H F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 3   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 60  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 120 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L  L ++   +
Sbjct: 180 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAETAKDWFL--LSAK---D 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 295 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 355 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 414

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 415 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 474 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 533

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 534 VTSHDSSTNGLINFIKQ 550
>ref|XP_867960.1| PREDICTED: similar to Glucose-6-phosphate isomerase (GPI)
           (Phosphoglucose isomerase) (PGI) (Phosphohexose
           isomerase) (PHI) (Neuroleukin) (NLK) (Sperm antigen-36)
           (SA-36) isoform 3 [Canis familiaris]
          Length = 563

 Score =  670 bits (1729), Expect = 0.0,   Method: Composition-based stats.
 Identities = 322/557 (57%), Positives = 416/557 (74%), Gaps = 7/557 (1%)

Query: 50  LTSCASWTQLQKLY-EQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQK + EQ  D  +++ FE D ER  R+S+ ++    +   + +DYSK+ +
Sbjct: 4   LTQSPQFQKLQKWHREQGSDLNLRRLFEGDKERFNRFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            D +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TDTVMQMLVDLAKSRGVEAARERMFSGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNRVLEKMKSFCQRVRSGEWKGYSGKPITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHI++ L +++ E++LFI+ASKTFTTQETITNA +A+   L   +   +  
Sbjct: 181 VWFVSNIDGTHISKTLAALNPESSLFIIASKTFTTQETITNAETAKEWFLLSAKDVNMSV 240

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 241 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 300

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 301 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETQAMLPYDQYLHRFAAYFQQG 360

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 361 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 420

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 421 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 479

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 480 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 539

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 540 VTSHDSSTNGLINFIKQ 556
>ref|NP_230028.1| glucose-6-phosphate isomerase [Vibrio cholerae O1 biovar eltor str.
           N16961]
 ref|ZP_01477742.1| hypothetical protein VchoM_02003128 [Vibrio cholerae MO10]
 ref|ZP_01678290.1| glucose-6-phosphate isomerase [Vibrio cholerae 2740-80]
 ref|ZP_01954494.1| glucose-6-phosphate isomerase [Vibrio cholerae MAK 757]
 ref|ZP_01957833.1| glucose-6-phosphate isomerase [Vibrio cholerae MZO-3]
 ref|ZP_01972901.1| glucose-6-phosphate isomerase [Vibrio cholerae NCTC 8457]
 ref|ZP_01976182.1| glucose-6-phosphate isomerase [Vibrio cholerae B33]
 sp|Q9KUY4|G6PI_VIBCH Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAF93547.1| glucose-6-phosphate isomerase [Vibrio cholerae O1 biovar eltor str.
           N16961]
 gb|EAX57323.1| glucose-6-phosphate isomerase [Vibrio cholerae 2740-80]
 gb|EAY36328.1| glucose-6-phosphate isomerase [Vibrio cholerae MAK 757]
 gb|EAY39970.1| glucose-6-phosphate isomerase [Vibrio cholerae MZO-3]
 gb|EAZ45869.1| glucose-6-phosphate isomerase [Vibrio cholerae MO10]
 gb|EAZ71815.1| glucose-6-phosphate isomerase [Vibrio cholerae NCTC 8457]
 gb|EAZ76183.1| glucose-6-phosphate isomerase [Vibrio cholerae B33]
          Length = 550

 Score =  670 bits (1729), Expect = 0.0,   Method: Composition-based stats.
 Identities = 332/551 (60%), Positives = 406/551 (73%), Gaps = 13/551 (2%)

Query: 51  TSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHIND 110
           T   +W  L   +E   D  +K  F  DSER  +YS +     +D   + +DYSK+ +N 
Sbjct: 8   TQTQAWKALTAHFESAQDMDLKALFAQDSERFAKYSARFG---QD---ILVDYSKNLVNA 61

Query: 111 EIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAV 170
           E    L  LA+E  ++  + ++F+GE +N TE+R VLH ALRNRSN P+ V+G+DVMPAV
Sbjct: 62  ETMQHLFALAKETDLQSAITAMFKGEAINQTEDRAVLHTALRNRSNSPVLVNGEDVMPAV 121

Query: 171 NKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLH 230
           N VL +M++FSE+V  GEWKG TGKAI  VVNIGIGGSDLGP M TEAL P+ +  L++H
Sbjct: 122 NAVLAKMKAFSERVIGGEWKGFTGKAITDVVNIGIGGSDLGPYMVTEALVPY-KNHLTMH 180

Query: 231 FVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKG 290
           FVSNVDGTH+AE LK++D E TLF+VASKTFTTQET+TNA +AR   L     +   ++ 
Sbjct: 181 FVSNVDGTHMAETLKNVDPETTLFLVASKTFTTQETMTNAHTARDWFL-----KAAGDEA 235

Query: 291 SVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELL 350
            VAKHF ALSTN + V EFGID +NMF+FWDWVGGRYS+WSAIGL I++SIGY+NFVELL
Sbjct: 236 HVAKHFAALSTNGKAVAEFGIDTDNMFEFWDWVGGRYSLWSAIGLSIILSIGYDNFVELL 295

Query: 351 TGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDM 410
            GAH +D+HF N P E N+P++LAL+G+WY NF GA + AILPYDQYL R  AY QQ +M
Sbjct: 296 AGAHEMDQHFVNTPFESNIPVILALIGIWYNNFHGAESEAILPYDQYLHRFAAYFQQGNM 355

Query: 411 ESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIG 470
           ESNGKYV R+G  V+  TGPII+GE GTNGQHAFYQLIHQGT LIPCDFI    S N +G
Sbjct: 356 ESNGKYVDRNGNPVTYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAVSHNLVG 415

Query: 471 DHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLL 530
           DHH+  MSNFFAQTEAL  GKS   V+ ELE AG+ +AE I AL+P K F G RP+N++L
Sbjct: 416 DHHQKLMSNFFAQTEALAFGKSAQAVQAELEKAGKSAAE-IAALVPFKVFEGNRPTNSIL 474

Query: 531 IKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNH 590
           +K +TPR LG +IAMYEHK+ VQG IW I S+DQWGVELGK LA  ILP+L     V +H
Sbjct: 475 VKQITPRTLGNLIAMYEHKIFVQGVIWNIFSFDQWGVELGKQLANQILPELADSAAVTSH 534

Query: 591 DSSTNGLINMF 601
           DSSTNGLIN F
Sbjct: 535 DSSTNGLINAF 545
>ref|ZP_01682182.1| glucose-6-phosphate isomerase [Vibrio cholerae V52]
 ref|YP_001218643.1| glucose-6-phosphate isomerase [Vibrio cholerae O395]
 ref|ZP_01979942.1| glucose-6-phosphate isomerase [Vibrio cholerae MZO-2]
 sp|A5F3J3|G6PI_VIBC3 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|EAX61011.1| glucose-6-phosphate isomerase [Vibrio cholerae V52]
 gb|ABQ21077.1| glucose-6-phosphate isomerase [Vibrio cholerae O395]
 gb|EDM53165.1| glucose-6-phosphate isomerase [Vibrio cholerae MZO-2]
          Length = 550

 Score =  670 bits (1728), Expect = 0.0,   Method: Composition-based stats.
 Identities = 332/551 (60%), Positives = 405/551 (73%), Gaps = 13/551 (2%)

Query: 51  TSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHIND 110
           T   +W  L   +E   D  +K  F  DSER  +YS +     +D   + +DYSK+ +N 
Sbjct: 8   TQTQAWKALTAHFESAQDMDLKALFAQDSERFAKYSARFG---QD---ILVDYSKNLVNA 61

Query: 111 EIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAV 170
           E    L  LA+E  ++  + ++F+GE +N TE+R VLH ALRNRSN P+ V+G+DVMPAV
Sbjct: 62  ETMQHLFALAKETDLQSAITAMFKGEAINQTEDRAVLHTALRNRSNSPVLVNGEDVMPAV 121

Query: 171 NKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLH 230
           N VL +M++FSE+V  GEWKG TGKAI  VVNIGIGGSDLGP M TEAL P+ +  L++H
Sbjct: 122 NAVLAKMKAFSERVIGGEWKGFTGKAITDVVNIGIGGSDLGPYMVTEALVPY-KNHLTMH 180

Query: 231 FVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKG 290
           FVSNVDGTH+AE LK++D E TLF+VASKTFTTQET+TNA +AR   L     +   ++ 
Sbjct: 181 FVSNVDGTHMAETLKNVDPETTLFLVASKTFTTQETMTNAHTARDWFL-----KAAGDEA 235

Query: 291 SVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELL 350
            VAKHF ALSTN + V EFGID +NMF+FWDWVGGRYS+WSAIGL I++SIGY+NFVELL
Sbjct: 236 HVAKHFAALSTNGKAVAEFGIDTDNMFEFWDWVGGRYSLWSAIGLSIILSIGYDNFVELL 295

Query: 351 TGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDM 410
            GAH +D+HF N P E N+P++LAL+G+WY NF GA + AILPYDQYL R  AY QQ +M
Sbjct: 296 AGAHEMDQHFVNTPFESNIPVILALIGIWYNNFHGAESEAILPYDQYLHRFAAYFQQGNM 355

Query: 411 ESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIG 470
           ESNGKYV R G  V+  TGPII+GE GTNGQHAFYQLIHQGT LIPCDFI    S N +G
Sbjct: 356 ESNGKYVDRDGNPVTYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAVSHNLVG 415

Query: 471 DHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLL 530
           DHH+  MSNFFAQTEAL  GKS   V+ ELE AG+ +AE I AL+P K F G RP+N++L
Sbjct: 416 DHHQKLMSNFFAQTEALAFGKSAQAVQAELEKAGKSAAE-IAALVPFKVFEGNRPTNSIL 474

Query: 531 IKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNH 590
           +K +TPR LG +IAMYEHK+ VQG IW I S+DQWGVELGK LA  ILP+L     V +H
Sbjct: 475 VKQITPRTLGNLIAMYEHKIFVQGVIWNIFSFDQWGVELGKQLANQILPELADSAAVTSH 534

Query: 591 DSSTNGLINMF 601
           DSSTNGLIN F
Sbjct: 535 DSSTNGLINAF 545
>ref|ZP_01481622.1| hypothetical protein VchoR_02002478 [Vibrio cholerae RC385]
 ref|ZP_01950557.1| glucose-6-phosphate isomerase [Vibrio cholerae 1587]
 ref|ZP_01983132.1| glucose-6-phosphate isomerase [Vibrio cholerae 623-39]
 gb|EAY32981.1| glucose-6-phosphate isomerase [Vibrio cholerae 1587]
 gb|EDL72202.1| glucose-6-phosphate isomerase [Vibrio cholerae 623-39]
 gb|EDN11611.1| glucose-6-phosphate isomerase [Vibrio cholerae RC385]
          Length = 550

 Score =  670 bits (1728), Expect = 0.0,   Method: Composition-based stats.
 Identities = 332/551 (60%), Positives = 405/551 (73%), Gaps = 13/551 (2%)

Query: 51  TSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHIND 110
           T   +W  L   +E   D  +K  F  DSER  +YS +     +D   + +DYSK+ +N 
Sbjct: 8   TQTQAWKALTAHFESAQDMDLKALFAQDSERFAKYSARFG---QD---ILVDYSKNLVNA 61

Query: 111 EIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAV 170
           E    L  LA+E  ++  + ++F+GE +N TE+R VLH ALRNRSN P+ V+G+DVMPAV
Sbjct: 62  ETMQHLFALAKETDLQSAITAMFKGEAINQTEDRAVLHTALRNRSNSPVLVNGEDVMPAV 121

Query: 171 NKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLH 230
           N VL +M++FSE+V  GEWKG TGKAI  VVNIGIGGSDLGP M TEAL P+ +  L++H
Sbjct: 122 NAVLAKMKAFSERVIGGEWKGFTGKAITDVVNIGIGGSDLGPYMVTEALVPY-KNHLTMH 180

Query: 231 FVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKG 290
           FVSNVDGTH+AE LK++D E TLF+VASKTFTTQET+TNA +AR   L     +   ++ 
Sbjct: 181 FVSNVDGTHMAETLKNVDPETTLFLVASKTFTTQETMTNAHTARDWFL-----KAAGDEA 235

Query: 291 SVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELL 350
            VAKHF ALSTN + V EFGID +NMF+FWDWVGGRYS+WSAIGL I++SIGY+NFVELL
Sbjct: 236 HVAKHFAALSTNGKAVAEFGIDTDNMFEFWDWVGGRYSLWSAIGLSIILSIGYDNFVELL 295

Query: 351 TGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDM 410
            GAH +D+HF N P E N+P++LAL+G+WY NF GA + AILPYDQYL R  AY QQ +M
Sbjct: 296 AGAHEMDQHFVNTPFESNIPVILALIGIWYNNFHGAESEAILPYDQYLHRFAAYFQQGNM 355

Query: 411 ESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIG 470
           ESNGKYV R G  V+  TGPII+GE GTNGQHAFYQLIHQGT LIPCDFI    S N +G
Sbjct: 356 ESNGKYVDRDGNPVTYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAVSHNLVG 415

Query: 471 DHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLL 530
           DHH+  MSNFFAQTEAL  GKS   V+ ELE AG+ +AE I AL+P K F G RP+N++L
Sbjct: 416 DHHQKLMSNFFAQTEALAFGKSAQTVQAELEKAGKSAAE-IAALVPFKVFEGNRPTNSIL 474

Query: 531 IKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNH 590
           +K +TPR LG +IAMYEHK+ VQG IW I S+DQWGVELGK LA  ILP+L     V +H
Sbjct: 475 VKQITPRTLGNLIAMYEHKIFVQGVIWNIFSFDQWGVELGKQLANQILPELADSAAVTSH 534

Query: 591 DSSTNGLINMF 601
           DSSTNGLIN F
Sbjct: 535 DSSTNGLINAF 545
>gb|AAR89393.1| glucose-6-phosphate isomerase [Trypanosoma cruzi]
          Length = 397

 Score =  670 bits (1728), Expect = 0.0,   Method: Composition-based stats.
 Identities = 310/397 (78%), Positives = 354/397 (89%)

Query: 160 YVDGKDVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEAL 219
           +V+G DVM  VNKVL+QM+  SEKVR GEWKG +GK IRHVVNIGIGGSDLGP+MA EAL
Sbjct: 1   FVNGNDVMHLVNKVLEQMKKLSEKVRRGEWKGQSGKPIRHVVNIGIGGSDLGPMMACEAL 60

Query: 220 KPFSQRDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLD 279
           KPFS R +S+HFVSN+DGTH++EVLK +D+E+TLFI+ASKTFTTQETITNALSAR   L 
Sbjct: 61  KPFSDRRISMHFVSNIDGTHLSEVLKLVDLESTLFIIASKTFTTQETITNALSARSEFLK 120

Query: 280 YLRSRGIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMI 339
           +L SRGI E G+VAKHFVALSTN +KVKEFGIDE NMFQFWDWVGGRYS+WSAIGL +MI
Sbjct: 121 FLSSRGIPEAGAVAKHFVALSTNAEKVKEFGIDEANMFQFWDWVGGRYSLWSAIGLSVMI 180

Query: 340 SIGYENFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLW 399
           SIGY+NFVE LTGAH++DEHF NAP E N+P++LALVG+WY NFFG+ T AILPYDQYLW
Sbjct: 181 SIGYDNFVEFLTGAHIMDEHFINAPTENNLPIILALVGIWYNNFFGSETQAILPYDQYLW 240

Query: 400 RLPAYLQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDF 459
           RLPAYLQQLDMESNGK  T++G+ VST TGPIIFGEAGTNGQHAFYQLIHQGT LIPCDF
Sbjct: 241 RLPAYLQQLDMESNGKGATKNGRMVSTHTGPIIFGEAGTNGQHAFYQLIHQGTKLIPCDF 300

Query: 460 IGAIQSQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKT 519
           IGAIQ+QN IG+HH+I MSNFFAQTEALMIGK+P EV+RELE+AG +S ++I  L+P KT
Sbjct: 301 IGAIQTQNCIGEHHRILMSNFFAQTEALMIGKTPEEVKRELESAGGKSEDEIQLLIPQKT 360

Query: 520 FIGGRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAI 556
           F GGRPSN+LL+K+LTPRALGAIIAMYEHKVLVQGAI
Sbjct: 361 FTGGRPSNSLLVKALTPRALGAIIAMYEHKVLVQGAI 397
Searching..................................................done Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|XP_867960.1|  PREDICTED: similar to Glucose-6-phosphate ...  1138   0.0  
ref|XP_853858.1|  PREDICTED: similar to Glucose-6-phosphate ...  1136   0.0  
pdb|1GZD|A  Chain A, Crystal Structure Of Pig Phosphoglucose...  1132   0.0  
ref|NP_999495.1|  glucose phosphate isomerase [Sus scrofa] >...  1132   0.0  
ref|XP_867967.1|  PREDICTED: similar to Glucose-6-phosphate ...  1131   0.0  
ref|NP_001035561.1|  glucose phosphate isomerase [Bos taurus...  1127   0.0  
sp|P13377|G6PI_TRYBB  Glucose-6-phosphate isomerase, glycoso...  1127   0.0  
pdb|1IAT|A  Chain A, Crystal Structure Of Human Phosphogluco...  1125   0.0  
ref|NP_000166.2|  glucose phosphate isomerase [Homo sapiens]...  1125   0.0  
gb|AAP36518.1|  Homo sapiens glucose phosphate isomerase [sy...  1125   0.0  
sp|Q4R591|G6PI_MACFA  Glucose-6-phosphate isomerase (GPI) (P...  1125   0.0  
ref|XP_001219077.1|  glucose-6-phosphate isomerase, glycosom...  1124   0.0  
pdb|1JLH|A  Chain A, Human Glucose-6-Phosphate Isomerase >gi...  1123   0.0  
pdb|2O2C|A  Chain A, Crystal Structure Of Phosphoglucose Iso...  1121   0.0  
gb|AAF22645.1|AF187554_1  sperm antigen-36 [Homo sapiens]        1121   0.0  
gb|AAA36368.1|  neuroleukin >gi|1336765|gb|AAB36062.1| gluco...  1120   0.0  
pdb|1N8T|A  Chain A, The Crystal Structure Of Phosphoglucose...  1118   0.0  
ref|NP_001075538.1|  phosphoglucose isomerase [Oryctolagus c...  1118   0.0  
pdb|1DQR|A  Chain A, Crystal Structure Of Rabbit Phosphogluc...  1118   0.0  
pdb|1G98|A  Chain A, Crystal Structure Analysis Of Rabbit Ph...  1118   0.0  
sp|Q5R4E3|G6PI_PONPY  Glucose-6-phosphate isomerase (GPI) (P...  1115   0.0  
ref|NP_997475.1|  glucose phosphate isomerase [Rattus norveg...  1110   0.0  
ref|NP_032181.1|  glucose phosphate isomerase 1 [Mus musculu...  1110   0.0  
sp|P06745|G6PI_MOUSE  Glucose-6-phosphate isomerase (GPI) (P...  1109   0.0  
pdb|2CVP|A  Chain A, Crystal Structure Of Mouse Amf >gi|1091...  1109   0.0  
prf||1405328A  phosphohexose isomerase                           1106   0.0  
dbj|BAE23502.1|  unnamed protein product [Mus musculus]          1106   0.0  
pdb|1U0E|A  Chain A, Crystal Structure Of Mouse Phosphogluco...  1106   0.0  
dbj|BAE21866.1|  unnamed protein product [Mus musculus]          1106   0.0  
dbj|BAE22329.1|  unnamed protein product [Mus musculus]          1106   0.0  
dbj|BAE35416.1|  unnamed protein product [Mus musculus]          1106   0.0  
sp|P50309|G6PI_CRIGR  Glucose-6-phosphate isomerase (GPI) (P...  1103   0.0  
emb|CAC83783.1|  phosphoglucose isomerase [Bufo melanostictus]   1101   0.0  
dbj|BAF91562.1|  phosphoglucose isomerase [Lepisosteus osseus]   1100   0.0  
ref|XP_001490657.1|  PREDICTED: similar to Glucose phosphate...  1099   0.0  
ref|NP_001006128.1|  glucose phosphate isomerase [Gallus gal...  1095   0.0  
gb|AAH83507.1|  Glucose phosphate isomerase a [Danio rerio]      1095   0.0  
dbj|BAF91559.1|  phosphoglucose isomerase [Polypterus ornati...  1094   0.0  
ref|YP_001746414.1|  glucose-6-phosphate isomerase [Escheric...  1093   0.0  
ref|NP_001085765.1|  MGC80718 protein [Xenopus laevis] >gi|4...  1093   0.0  
ref|ZP_00724931.1|  COG0166: Glucose-6-phosphate isomerase [...  1093   0.0  
ref|YP_543532.1|  glucose-6-phosphate isomerase [Escherichia...  1093   0.0  
dbj|BAF91563.1|  phosphoglucose isomerase [Acipenser ruthenus]   1093   0.0  
ref|NP_290659.1|  glucose-6-phosphate isomerase [Escherichia...  1092   0.0  
ref|ZP_00711964.1|  COG0166: Glucose-6-phosphate isomerase [...  1092   0.0  
dbj|BAF91556.1|  phosphoglucose isomerase [Amia calva]           1091   0.0  
ref|XP_820895.1|  glucose-6-phosphate isomerase, glycosomal,...  1091   0.0  
gb|AAH44450.1|  Glucose phosphate isomerase a [Danio rerio]      1091   0.0  
ref|XP_867955.1|  PREDICTED: similar to Glucose-6-phosphate ...  1091   0.0  
ref|NP_838787.1|  glucose-6-phosphate isomerase [Shigella fl...  1091   0.0  
ref|YP_691477.1|  glucose-6-phosphate isomerase [Shigella fl...  1091   0.0  
ref|XP_001365167.1|  PREDICTED: similar to phosphoglucose is...  1090   0.0  
ref|YP_001008017.1|  glucose-6-phosphate isomerase [Yersinia...  1090   0.0  
emb|CAA33268.1|  unnamed protein product [Escherichia coli]      1090   0.0  
ref|NP_407169.1|  glucose-6-phosphate isomerase [Yersinia pe...  1090   0.0  
emb|CAC83780.1|  phosphoglucose isomerase [Boiga kraepelini]     1090   0.0  
dbj|BAF91558.1|  phosphoglucose isomerase-2 [Osteoglossum bi...  1090   0.0  
ref|XP_001463984.1|  glucose-6-phosphate isomerase [Leishman...  1089   0.0  
emb|CAF05827.1|  glucose-6-phosphate isomerase [Leishmania d...  1088   0.0  
emb|CAF05824.1|  glucose-6-phosphate isomerase [Leishmania d...  1088   0.0  
emb|CAC83779.1|  phosphoglucose isomerase-2 [Mugil cephalus]     1088   0.0  
ref|NP_994374.1|  glucose-6-phosphate isomerase [Yersinia pe...  1088   0.0  
emb|CAF05839.1|  glucose-6-phosphate isomerase [Leishmania d...  1087   0.0  
ref|YP_677101.1|  glucose-6-phosphate isomerase [Cytophaga h...  1086   0.0  
emb|CAF05831.1|  glucose-6-phosphate isomerase [Leishmania i...  1086   0.0  
emb|CAF05819.1|  glucose-6-phosphate isomerase [Leishmania i...  1086   0.0  
ref|ZP_02903962.1|  glucose-6-phosphate isomerase [Escherich...  1086   0.0  
dbj|BAF91560.1|  phosphoglucose isomerase-1 [Anguilla anguilla]  1086   0.0  
emb|CAC83778.1|  phosphoglucose isomerase [Mugil cephalus]       1085   0.0  
ref|XP_001681659.1|  glucose-6-phosphate isomerase [Leishman...  1085   0.0  
ref|NP_001011010.1|  glucose phosphate isomerase [Xenopus tr...  1085   0.0  
dbj|BAF91561.1|  phosphoglucose isomerase-2 [Anguilla anguilla]  1085   0.0  
ref|XP_821969.1|  glucose-6-phosphate isomerase, glycosomal,...  1084   0.0  
sp|P42861|G6PI_LEIME  Glucose-6-phosphate isomerase (GPI) (P...  1083   0.0  
ref|YP_001436210.1|  hypothetical protein ESA_00069 [Enterob...  1083   0.0  
gb|AAI21195.1|  Gpib protein [Danio rerio]                       1083   0.0  
ref|YP_001480699.1|  Glucose-6-phosphate isomerase [Serratia...  1082   0.0  
dbj|BAF91557.1|  phosphoglucose isomerase-1 [Osteoglossum bi...  1081   0.0  
ref|NP_658909.1|  glucose phosphate isomerase a [Danio rerio...  1081   0.0  
ref|YP_001455405.1|  hypothetical protein CKO_03893 [Citroba...  1080   0.0  
emb|CAP09263.1|  glucose phosphate isomerase b [Danio rerio]     1080   0.0  
ref|ZP_02705383.1|  hypothetical protein Salmoentericaenteri...  1079   0.0  
ref|ZP_03900221.1|  glucose-6-phosphate isomerase [Dyadobact...  1079   0.0  
ref|YP_219087.1|  glucose-6-phosphate isomerase [Salmonella ...  1079   0.0  
ref|ZP_02685434.1|  glucose-6-phosphate isomerase [Salmonell...  1079   0.0  
dbj|BAF91566.1|  phosphoglucose isomerase-2 [Plecoglossus al...  1079   0.0  
ref|ZP_02561519.1|  hypothetical protein Sente_14948 [Salmon...  1079   0.0  
ref|NP_458519.1|  glucose-6-phosphate isomerase [Salmonella ...  1078   0.0  
ref|YP_001338035.1|  glucose-6-phosphate isomerase [Klebsiel...  1078   0.0  
ref|NP_463086.1|  glucose-6-phosphate isomerase [Salmonella ...  1078   0.0  
gb|EEH96038.1|  glucose-6-phosphate isomerase [Citrobacter s...  1078   0.0  
ref|ZP_03838871.1|  glucose-6-phosphate isomerase [Citrobact...  1078   0.0  
ref|YP_001572432.1|  hypothetical protein SARI_03461 [Salmon...  1078   0.0  
ref|ZP_02700747.1|  hypothetical protein Saentericaenterica_...  1078   0.0  
ref|ZP_02644649.1|  hypothetical protein Senterenterica_0343...  1078   0.0  
ref|ZP_02567671.1|  glucose-6-phosphate isomerase [Salmonell...  1077   0.0  
ref|ZP_00828371.1|  COG0166: Glucose-6-phosphate isomerase [...  1077   0.0  
ref|ZP_02133202.1|  Transketolase [Desulfatibacillum alkeniv...  1077   0.0  
ref|ZP_02680981.1|  hypothetical protein Sentericaenterica_2...  1076   0.0  
ref|ZP_02833339.1|  hypothetical protein Salentericaenterica...  1076   0.0  
gb|ABB76196.1|  phosphoglucose isomerase [Colias eurytheme]      1076   0.0  
gb|ABB76192.1|  phosphoglucose isomerase [Colias eurytheme]      1075   0.0  
ref|YP_854687.1|  glucose-6-phosphate isomerase [Aeromonas h...  1075   0.0  
ref|YP_153096.1|  glucose-6-phosphate isomerase [Salmonella ...  1075   0.0  
dbj|BAF91565.1|  phosphoglucose isomerase-1 [Plecoglossus al...  1075   0.0  
ref|NP_658910.1|  glucose phosphate isomerase b [Danio rerio...  1075   0.0  
ref|ZP_03827475.1|  glucose-6-phosphate isomerase [Pectobact...  1075   0.0  
gb|ABB76189.1|  phosphoglucose isomerase [Colias eurytheme]      1074   0.0  
gb|ABB76190.1|  phosphoglucose isomerase [Colias eurytheme]      1074   0.0  
gb|ABB76191.1|  phosphoglucose isomerase [Colias eurytheme]      1074   0.0  
gb|ABB00833.1|  phosphoglucose isomerase [Colias eurytheme]      1073   0.0  
ref|YP_052066.1|  glucose-6-phosphate isomerase [Erwinia car...  1073   0.0  
ref|ZP_01237153.1|  glucose-6-phosphate isomerase [Vibrio an...  1073   0.0  
emb|CAC83777.1|  phosphoglucose isomerase [Paramyxine yangi]     1073   0.0  
ref|ZP_00824080.1|  COG0166: Glucose-6-phosphate isomerase [...  1073   0.0  
ref|ZP_01261693.1|  glucose-6-phosphate isomerase [Vibrio al...  1073   0.0  
gb|ABB76200.1|  phosphoglucose isomerase [Colias meadii]         1072   0.0  
ref|NP_760318.1|  glucose-6-phosphate isomerase [Vibrio vuln...  1072   0.0  
gb|ABB76201.1|  phosphoglucose isomerase [Colias meadii]         1072   0.0  
gb|ABB76195.1|  phosphoglucose isomerase [Colias eurytheme]      1072   0.0  
gb|ABB76197.1|  phosphoglucose isomerase [Colias eurytheme]      1072   0.0  
ref|NP_931552.1|  glucose-6-phosphate isomerase [Photorhabdu...  1072   0.0  
gb|AAP33062.1|  phosphoglucose isomerase [Vibrio vulnificus]     1072   0.0  
ref|NP_935768.1|  glucose-6-phosphate isomerase [Vibrio vuln...  1071   0.0  
ref|ZP_00821566.1|  COG0166: Glucose-6-phosphate isomerase [...  1071   0.0  
gb|ABB76198.1|  phosphoglucose isomerase [Colias eurytheme]      1071   0.0  
gb|ABB76199.1|  phosphoglucose isomerase [Colias eurytheme]      1071   0.0  
ref|ZP_03830266.1|  glucose-6-phosphate isomerase [Pectobact...  1071   0.0  
ref|NP_799110.1|  glucose-6-phosphate isomerase [Vibrio para...  1071   0.0  
ref|YP_455826.1|  glucose-6-phosphate isomerase [Sodalis glo...  1070   0.0  
ref|ZP_01162337.1|  glucose-6-phosphate isomerase [Photobact...  1070   0.0  
gb|ABB76188.1|  phosphoglucose isomerase [Colias eurytheme]      1069   0.0  
ref|ZP_03842012.1|  glucose-6-phosphate isomerase [Proteus m...  1069   0.0  
ref|XP_001510188.1|  PREDICTED: hypothetical protein [Ornith...  1069   0.0  
ref|NP_001091761.1|  glucose-6-phosphate isomerase [Bombyx m...  1069   0.0  
ref|ZP_01473793.1|  hypothetical protein VEx2w_02003634 [Vib...  1069   0.0  
ref|ZP_01481622.1|  hypothetical protein VchoR_02002478 [Vib...  1069   0.0  
ref|ZP_01682182.1|  glucose-6-phosphate isomerase [Vibrio ch...  1068   0.0  
ref|YP_001143911.1|  glucose-6-phosphate isomerase [Aeromona...  1068   0.0  
ref|XP_970258.1|  PREDICTED: similar to Glucose-6-phosphate ...  1068   0.0  
ref|NP_230028.1|  glucose-6-phosphate isomerase [Vibrio chol...  1068   0.0  
ref|YP_001909025.1|  Glucose-6-phosphate isomerase (Phosphog...  1067   0.0  
ref|ZP_02961946.1|  hypothetical protein PROSTU_04029 [Provi...  1066   0.0  
ref|YP_001174971.1|  glucose-6-phosphate isomerase [Enteroba...  1066   0.0  
ref|ZP_00832585.1|  COG0166: Glucose-6-phosphate isomerase [...  1066   0.0  
ref|YP_001443299.1|  glucose-6-phosphate isomerase [Vibrio h...  1066   0.0  
ref|ZP_01450980.1|  glucose-6-phosphate isomerase [Mariprofu...  1065   0.0  
gb|EDN15559.1|  glucose-6-phosphate isomerase [Vibrio choler...  1064   0.0  
emb|CAJ73656.1|  strongly similar to glucose-6-phosphate iso...  1063   0.0  
ref|ZP_00157128.2|  COG0166: Glucose-6-phosphate isomerase [...  1063   0.0  
gb|AAX88290.1|  glucose-6-phosphate isomerase [Haemophilus i...  1063   0.0  
ref|ZP_02478614.1|  hypothetical protein HPS_11202 [Haemophi...  1062   0.0  
ref|ZP_01795487.1|  glucose-6-phosphate isomerase [Haemophil...  1062   0.0  
ref|YP_248950.2|  glucose-6-phosphate isomerase [Haemophilus...  1061   0.0  
ref|XP_001599986.1|  PREDICTED: similar to phosphoglucose is...  1061   0.0  
ref|ZP_02197004.1|  glucose-6-phosphate isomerase [Vibrio ca...  1061   0.0  
ref|NP_245353.1|  glucose-6-phosphate isomerase [Pasteurella...  1061   0.0  
ref|YP_719149.1|  glucose-6-phosphate isomerase [Haemophilus...  1060   0.0  
ref|ZP_01793484.1|  glucose-6-phosphate isomerase [Haemophil...  1060   0.0  
ref|ZP_01786798.1|  glucose-6-phosphate isomerase [Haemophil...  1060   0.0  
ref|YP_001290850.1|  glucose-6-phosphate isomerase [Haemophi...  1059   0.0  
ref|ZP_01791410.1|  glucose-6-phosphate isomerase [Haemophil...  1059   0.0  
ref|ZP_01869965.1|  glucose-6-phosphate isomerase [Vibrio sh...  1058   0.0  
ref|ZP_01788697.1|  glucose-6-phosphate isomerase [Haemophil...  1057   0.0  
ref|YP_001784733.1|  Glucose-6-phosphate isomerase [Haemophi...  1056   0.0  
ref|YP_203687.1|  glucosephosphate isomerase [Vibrio fischer...  1056   0.0  
ref|YP_001291516.1|  glucose-6-phosphate isomerase [Haemophi...  1056   0.0  
ref|ZP_00155145.1|  COG0166: Glucose-6-phosphate isomerase [...  1055   0.0  
ref|YP_001053832.1|  glucose-6-phosphate isomerase [Actinoba...  1055   0.0  
gb|AAC23219.1|  glucose-6-phosphate isomerase (pgi) [Haemoph...  1054   0.0  
ref|ZP_01816475.1|  glucose-6-phosphate isomerase [Vibrional...  1054   0.0  
gb|EDN74431.1|  glucose-6-phosphate isomerase [Mannheimia ha...  1054   0.0  
ref|ZP_00135214.1|  COG0166: Glucose-6-phosphate isomerase [...  1054   0.0  
ref|NP_439722.2|  glucose-6-phosphate isomerase [Haemophilus...  1054   0.0  
ref|YP_001652156.1|  glucose-6-phosphate isomerase [Actinoba...  1053   0.0  
ref|ZP_01066513.1|  glucose-6-phosphate isomerase [Vibrio sp...  1051   0.0  
ref|ZP_00991932.1|  glucose-6-phosphate isomerase [Vibrio sp...  1051   0.0  
ref|YP_131428.1|  glucose-6-phosphate isomerase [Photobacter...  1050   0.0  
sp|Q1H1P4|G6PI_METFK  Glucose-6-phosphate isomerase (GPI) (P...  1049   0.0  
ref|ZP_01222432.1|  glucose-6-phosphate isomerase [Photobact...  1049   0.0  
ref|XP_001629102.1|  predicted protein [Nematostella vectens...  1048   0.0  
ref|ZP_01883305.1|  glucose-6-phosphate isomerase [Pedobacte...  1047   0.0  
ref|YP_847696.1|  phosphoglucose isomerase (PGI) [Syntrophob...  1046   0.0  
ref|YP_088373.1|  glucose-6-phosphate isomerase [Mannheimia ...  1046   0.0  
sp|P52030|G6PI_DROSI  Glucose-6-phosphate isomerase (GPI) (P...  1046   0.0  
ref|XP_001749895.1|  predicted protein [Monosiga brevicollis...  1046   0.0  
sp|P52031|G6PI_DROYA  Glucose-6-phosphate isomerase (GPI) (P...  1045   0.0  
ref|YP_001344719.1|  Glucose-6-phosphate isomerase [Actinoba...  1045   0.0  
gb|AAA28809.1|  glucose-6-phosphate isomerase                    1045   0.0  
gb|AAA28797.1|  glucosephosphate isomerase >gi|443615|gb|AAA...  1044   0.0  
ref|ZP_01215739.1|  glucose-6-phosphate isomerase [Psychromo...  1044   0.0  
gb|AAA28789.1|  glucosephosphate isomerase >gi|443601|gb|AAA...  1043   0.0  
ref|NP_523663.1|  Phosphoglucose isomerase CG8251-PA, isofor...  1043   0.0  
gb|AAA28813.1|  glucose-6-phosphate isomerase                    1043   0.0  
ref|XP_001361508.1|  GA20931-PA [Drosophila pseudoobscura] >...  1043   0.0  
gb|AAA63672.1|  glucosephosphate isomerase                       1043   0.0  
ref|ZP_00511177.1|  Glucose-6-phosphate isomerase [Chlorobiu...  1041   0.0  
gb|AAA28804.1|  glucose-6-phosphate isomerase                    1039   0.0  
ref|XP_001563099.1|  glucose-6-phosphate isomerase [Leishman...  1039   0.0  
gb|ABU25168.1|  glucose-6-phosphate isomerase [Leishmania la...  1039   0.0  
gb|ABU25166.1|  glucose-6-phosphate isomerase [Leishmania gu...  1038   0.0  
gb|ABU25165.1|  glucose-6-phosphate isomerase [Leishmania br...  1038   0.0  
ref|ZP_01900582.1|  glucose-6-phosphate isomerase [Moritella...  1038   0.0  
ref|XP_001663180.1|  glucose-6-phosphate isomerase [Aedes ae...  1038   0.0  
ref|YP_941789.1|  Glucose-6-phosphate isomerase [Psychromona...  1034   0.0  
ref|ZP_01386716.1|  Glucose-6-phosphate isomerase [Chlorobiu...  1034   0.0  
ref|ZP_00531578.1|  Glucose-6-phosphate isomerase [Chlorobiu...  1033   0.0  
ref|XP_001848359.1|  glucose-6-phosphate isomerase [Culex pi...  1033   0.0  
ref|YP_113710.1|  glucose-6-phosphate isomerase [Methylococc...  1032   0.0  
ref|XP_320366.3|  AGAP012167-PA [Anopheles gambiae str. PEST...  1031   0.0  
ref|XP_638957.1|  glucose-6-phosphate isomerase [Dictyosteli...  1028   0.0  
ref|ZP_01720871.1|  glucose-6-phosphate isomerase [Algoripha...  1028   0.0  
ref|YP_865849.1|  Glucose-6-phosphate isomerase [Magnetococc...  1027   0.0  
ref|YP_545434.1|  Glucose-6-phosphate isomerase [Methylobaci...  1027   0.0  
ref|XP_623552.1|  PREDICTED: similar to Glucose-6-phosphate ...  1026   0.0  
ref|YP_342945.1|  Glucose-6-phosphate isomerase [Nitrosococc...  1025   0.0  
ref|YP_378928.1|  glucose-6-phosphate isomerase [Chlorobium ...  1024   0.0  
ref|NP_872994.1|  glucose-6-phosphate isomerase [Haemophilus...  1024   0.0  
ref|NP_001021838.1|  Glucose-6-Phosphate Isomerase family me...  1024   0.0  
gb|ABH11436.1|  cytosolic glucose-6-phosphate isomerase [Pav...  1023   0.0  
ref|NP_295465.1|  glucose-6-phosphate isomerase [Deinococcus...  1023   0.0  
ref|ZP_00592941.1|  Glucose-6-phosphate isomerase [Prostheco...  1022   0.0  
ref|YP_375066.1|  Glucose-6-phosphate isomerase [Pelodictyon...  1021   0.0  
sp|Q3B3Q8|G6PI_PELLD  Glucose-6-phosphate isomerase (GPI) (P...  1021   0.0  
emb|CAP27938.1|  C. briggsae CBR-GPI-1 protein [Caenorhabdit...  1021   0.0  
gb|ABI49145.1|  glucose-6-phosphate isomerase [Trimastix pyr...  1021   0.0  
pdb|1Q50|A  Chain A, Phosphoglucose Isomerase From Leishmani...  1020   0.0  
ref|NP_001021837.1|  Glucose-6-Phosphate Isomerase family me...  1020   0.0  
ref|YP_001130308.1|  Glucose-6-phosphate isomerase [Prosthec...  1018   0.0  
ref|YP_002786433.1|  putative glucose-6-phosphate isomerase ...  1018   0.0  
gb|ABH11435.2|  cytosolic glucose-6-phosphate isomerase [Emi...  1017   0.0  
ref|XP_001900986.1|  glucose phosphate isomerase a [Brugia m...  1017   0.0  
ref|ZP_00588749.1|  Glucose-6-phosphate isomerase [Pelodicty...  1016   0.0  
ref|NP_661881.1|  glucose-6-phosphate isomerase [Chlorobium ...  1015   0.0  
gb|AAG15513.1|U65476_1  phosphoglucose isomerase; glucose-6-...  1014   0.0  
ref|YP_604769.1|  Glucose-6-phosphate isomerase [Deinococcus...  1012   0.0  
ref|YP_423777.1|  Glucose-6-phosphate isomerase [Magnetospir...  1010   0.0  
ref|ZP_00055322.1|  COG0166: Glucose-6-phosphate isomerase [...  1009   0.0  
gb|ABH11445.1|  cytosolic glucose-6-phosphate isomerase [Pha...  1009   0.0  
dbj|BAC36335.1|  unnamed protein product [Mus musculus]          1008   0.0  
sp|Q1IYT4|G6PI_DEIGD  Glucose-6-phosphate isomerase (GPI) (P...  1005   0.0  
dbj|BAE53447.1|  Glucosephosphate isomerase [Entamoeba histo...  1005   0.0  
ref|XP_650595.1|  glucose-6-phosphate isomerase, putative [E...  1005   0.0  
dbj|BAE53448.1|  Glucosephosphate isomerase [Entamoeba histo...  1005   0.0  
ref|YP_911560.1|  Glucose-6-phosphate isomerase [Chlorobium ...  1004   0.0  
ref|YP_315821.1|  glucose-6-phosphate isomerase [Thiobacillu...  1003   0.0  
emb|CAA82246.1|  glucosephosphate isomerase [Sus scrofa]         1003   0.0  
sp|Q3SH73|G6PI2_THIDA  Glucose-6-phosphate isomerase 2 (GPI ...  1002   0.0  
ref|XP_001741106.1|  glucose-6-phosphate isomerase, putative...   999   0.0  
ref|NP_924638.1|  glucose-6-phosphate isomerase [Gloeobacter...   998   0.0  
ref|ZP_01088891.1|  glucose-6-phosphate isomerase [Blastopir...   997   0.0  
dbj|BAF57007.1|  glucose-6-phosphate isomerase 1 [Entamoeba ...   994   0.0  
ref|NP_899819.1|  glucose-6-phosphate isomerase [Chromobacte...   993   0.0  
ref|YP_001430850.1|  Glucose-6-phosphate isomerase [Roseifle...   992   0.0  
dbj|BAF57008.1|  glucose-6-phosphate isomerase 2 [Entamoeba ...   991   0.0  
gb|ABS81352.1|  phosphoglucose isomerase [Echinococcus multi...   988   0.0  
gb|AAX73170.1|  putative glucose phosphate isomerase [Echino...   987   0.0  
ref|ZP_02733949.1|  glucose-6-phosphate isomerase [Gemmata o...   987   0.0  
ref|XP_001839617.1|  hypothetical protein CC1G_10610 [Coprin...   984   0.0  
ref|YP_428031.1|  Glucose-6-phosphate isomerase [Rhodospiril...   983   0.0  
ref|YP_588491.1|  glucose-6-phosphate isomerase [Baumannia c...   982   0.0  
gb|AAT91251.1|  Glc-6-P isomerase [Paxillus involutus]            980   0.0  
ref|YP_002754143.1|  glucose-6-phosphate isomerase [Acidobac...   980   0.0  
ref|ZP_01854838.1|  glucose-6-phosphate isomerase / glucose-...   979   0.0  
ref|YP_001278641.1|  glucose-6-phosphate isomerase [Roseifle...   978   0.0  
ref|ZP_03850867.1|  glucose-6-phosphate isomerase [Chryseoba...   977   0.0  
emb|CAM76547.1|  Glucose-6-phosphate isomerase [Magnetospiri...   977   0.0  
ref|NP_596635.1|  glucose-6-phosphate isomerase (predicted) ...   977   0.0  
ref|XP_777368.1|  hypothetical protein CNBB1690 [Cryptococcu...   976   0.0  
ref|XP_569228.1|  glucose-6-phosphate isomerase [Cryptococcu...   975   0.0  
gb|EDU44288.1|  glucose-6-phosphate isomerase [Pyrenophora t...   974   0.0  
ref|XP_001882557.1|  glucose-6-phosphate isomerase [Laccaria...   974   0.0  
ref|NP_274402.1|  glucose-6-phosphate isomerase [Neisseria m...   973   0.0  
ref|XP_001803813.1|  hypothetical protein SNOG_13608 [Phaeos...   973   0.0  
ref|YP_460809.1|  glucose-6-phosphate isomerase / glucose-6 ...   973   0.0  
ref|YP_001599432.1|  glucose-6-phosphate isomerase [Neisseri...   973   0.0  
ref|XP_001537093.1|  glucose-6-phosphate isomerase [Ajellomy...   972   0.0  
ref|XP_001240681.1|  glucose-6-phosphate isomerase [Coccidio...   972   0.0  
ref|YP_357776.2|  glucose phosphate isomerase [Pelobacter ca...   972   0.0  
ref|YP_975337.1|  glucose-6-phosphate isomerase [Neisseria m...   971   0.0  
ref|YP_207851.1|  glucose-6-phosphate isomerase [Neisseria g...   971   0.0  
dbj|BAG13901.1|  glucose-6-phosphate isomerase [uncultured T...   969   0.0  
ref|ZP_01797300.1|  glucose-6-phosphate isomerase [Haemophil...   969   0.0  
ref|NP_284321.1|  glucose-6-phosphate isomerase [Neisseria m...   969   0.0  
ref|YP_001827090.1|  putative glucose-6-phosphate isomerase ...   968   0.0  
sp|Q711G1|G6PI_AGABI  Glucose-6-phosphate isomerase (GPI) (P...   965   0.0  
ref|NP_009755.1|  Glycolytic enzyme phosphoglucose isomerase...   964   0.0  
ref|NP_827478.1|  glucose-6-phosphate isomerase [Streptomyce...   962   0.0  
dbj|BAA13929.1|  unnamed protein product [Schizosaccharomyce...   962   0.0  
ref|YP_001673349.1|  Glucose-6-phosphate isomerase [Shewanel...   962   0.0  
ref|YP_278131.1|  glucose-6-phosphate isomerase [Candidatus ...   962   0.0  
ref|XP_455013.1|  G6PI_KLULA [Kluyveromyces lactis] >gi|5278...   960   0.0  
ref|XP_460936.1|  hypothetical protein DEHA0F14289g [Debaryo...   960   0.0  
ref|XP_855506.1|  PREDICTED: similar to Glucose-6-phosphate ...   959   0.0  
ref|YP_411169.1|  glucose-6-phosphate isomerase [Nitrosospir...   959   0.0  
ref|ZP_01062120.1|  glucose-6-phosphate isomerase [Flavobact...   959   0.0  
sp|Q2YBU4|G6PI_NITMU  Glucose-6-phosphate isomerase (GPI) (P...   959   0.0  
ref|NP_878897.1|  glucose-6-phosphate isomerase [Candidatus ...   959   0.0  
ref|XP_001201424.1|  PREDICTED: similar to glucose-6-phospha...   957   0.0  
ref|YP_001500935.1|  Glucose-6-phosphate isomerase [Shewanel...   957   0.0  
Sequences not found previously or not previously below threshold:

>ref|XP_867960.1| PREDICTED: similar to Glucose-6-phosphate isomerase (GPI)
           (Phosphoglucose isomerase) (PGI) (Phosphohexose
           isomerase) (PHI) (Neuroleukin) (NLK) (Sperm antigen-36)
           (SA-36) isoform 3 [Canis familiaris]
          Length = 563

 Score = 1138 bits (2946), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/557 (57%), Positives = 416/557 (74%), Gaps = 7/557 (1%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQK + + G D  +++ FE D ER  R+S+ ++    +   + +DYSK+ +
Sbjct: 4   LTQSPQFQKLQKWHREQGSDLNLRRLFEGDKERFNRFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            D +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TDTVMQMLVDLAKSRGVEAARERMFSGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNRVLEKMKSFCQRVRSGEWKGYSGKPITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHI++ L +++ E++LFI+ASKTFTTQETITNA +A+   L   +   +  
Sbjct: 181 VWFVSNIDGTHISKTLAALNPESSLFIIASKTFTTQETITNAETAKEWFLLSAKDVNMSV 240

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 241 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 300

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 301 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETQAMLPYDQYLHRFAAYFQQG 360

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 361 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 420

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 421 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 479

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 480 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 539

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 540 VTSHDSSTNGLINFIKQ 556
>ref|XP_853858.1| PREDICTED: similar to Glucose-6-phosphate isomerase (GPI)
           (Phosphoglucose isomerase) (PGI) (Phosphohexose
           isomerase) (PHI) (Neuroleukin) (NLK) (Sperm antigen-36)
           (SA-36) isoform 1 [Canis familiaris]
          Length = 558

 Score = 1136 bits (2940), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/557 (57%), Positives = 415/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQK + + G D  +++ FE D ER  R+S+ ++    +   + +DYSK+ +
Sbjct: 4   LTQSPQFQKLQKWHREQGSDLNLRRLFEGDKERFNRFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            D +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TDTVMQMLVDLAKSRGVEAARERMFSGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNRVLEKMKSFCQRVRSGEWKGYSGKPITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHI++ L +++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 181 VWFVSNIDGTHISKTLAALNPESSLFIIASKTFTTQETITNAETAKEWFL-----LSAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETQAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 535 VTSHDSSTNGLINFIKQ 551
>pdb|1GZD|A Chain A, Crystal Structure Of Pig Phosphoglucose Isomerase
 pdb|1GZV|A Chain A, The Crystal Structure Of Phosphoglucose Isomerase From Pig
           Muscle Complexed With 5-Phosphoarabinonate
          Length = 557

 Score = 1132 bits (2930), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/557 (57%), Positives = 416/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ  Y ++  D  +++ FE D +R   +S+ ++    +   + LDYSK+ +
Sbjct: 3   LTQNPQFKKLQTWYHEHRSDLNLRRLFEGDKDRFNHFSLNLN---TNHGRILLDYSKNLV 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            + +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 60  TEAVMQMLVDLAKSRGVEAARERMFNGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK+I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 120 EVNRVLEKMKSFCKRVRSGEWKGYSGKSITDVINIGIGGSDLGPLMVTEALKPYSAEGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L +++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 180 VWFVSNIDGTHIAKTLATLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QSAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYINFFG  THA+LPYDQYL R  AY QQ 
Sbjct: 295 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINFFGCETHAMLPYDQYLHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 355 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 414

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E    LLPHK F G RP+
Sbjct: 415 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDFEKLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 474 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 533

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 534 VTSHDSSTNGLINFIKQ 550
>ref|NP_999495.1| glucose phosphate isomerase [Sus scrofa]
 sp|P08059|G6PI_PIG Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 emb|CAA30295.1| unnamed protein product [Sus scrofa]
          Length = 558

 Score = 1132 bits (2930), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/557 (57%), Positives = 416/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ  Y ++  D  +++ FE D +R   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTQNPQFKKLQTWYHEHRSDLNLRRLFEGDKDRFNHFSLNLN---TNHGRILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            + +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEAVMQMLVDLAKSRGVEAARERMFNGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK+I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNRVLEKMKSFCKRVRSGEWKGYSGKSITDVINIGIGGSDLGPLMVTEALKPYSAEGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L +++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWFVSNIDGTHIAKTLATLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QSAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYINFFG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINFFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E    LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDFEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 535 VTSHDSSTNGLINFIKQ 551
>ref|XP_867967.1| PREDICTED: similar to Glucose-6-phosphate isomerase (GPI)
           (Phosphoglucose isomerase) (PGI) (Phosphohexose
           isomerase) (PHI) (Neuroleukin) (NLK) (Sperm antigen-36)
           (SA-36) isoform 4 [Canis familiaris]
          Length = 561

 Score = 1131 bits (2928), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/557 (57%), Positives = 417/557 (74%), Gaps = 9/557 (1%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQK + + G D  +++ FE D ER  R+S+ ++    +   + +DYSK+ +
Sbjct: 4   LTQSPQFQKLQKWHREQGSDLNLRRLFEGDKERFNRFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            D +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TDTVMQMLVDLAKSRGVEAARERMFSGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNRVLEKMKSFCQRVRSGEWKGYSGKPITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHI++ L +++ E++LFI+ASKTFTTQETITNA +A+   L  L ++ +  
Sbjct: 181 VWFVSNIDGTHISKTLAALNPESSLFIIASKTFTTQETITNAETAKEWFL--LSAKDVSA 238

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
              +AKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 239 GVGIAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 298

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 299 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETQAMLPYDQYLHRFAAYFQQG 358

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 359 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 418

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 419 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 477

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 478 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 537

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 538 VTSHDSSTNGLINFIKQ 554
>ref|NP_001035561.1| glucose phosphate isomerase [Bos taurus]
 sp|Q3ZBD7|G6PI_BOVIN Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAI03417.1| Glucose phosphate isomerase [Bos taurus]
          Length = 557

 Score = 1127 bits (2917), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/557 (57%), Positives = 418/557 (75%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L+  YEQ+G D  +++ FE D +R  R+S+ ++    +   + +DYSK+ +
Sbjct: 4   LTQNPQFKKLKTWYEQHGSDLNLRRLFEGDRDRFNRFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            + +   L+ +A+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TETVMQMLVDVAKSRGVEAARERMFTGEKINFTEDRAVLHVALRNRSNAPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GKAI  V+NIGIGGSDLGP+M TE+LKP+S     
Sbjct: 121 EVNRVLEKMKSFCQRVRSGEWKGYSGKAITDVINIGIGGSDLGPLMVTESLKPYSSEGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L +++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 181 VWFVSNIDGTHIAKTLATLNPESSLFIIASKTFTTQETITNAETAKEWFL-----LSAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V+  TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +QSQ+ 
Sbjct: 356 DMESNGKYITKSGTRVNYQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQSQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG RS E    LLPHK F G RP+
Sbjct: 416 IRNGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-RSPEDFEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 535 VTSHDSSTNGLINFIKQ 551
>sp|P13377|G6PI_TRYBB Glucose-6-phosphate isomerase, glycosomal (GPI) (Phosphoglucose
           isomerase) (PGI) (Phosphohexose isomerase) (PHI)
 emb|CAA33547.1| unnamed protein product [Trypanosoma brucei]
          Length = 607

 Score = 1127 bits (2916), Expect = 0.0,   Method: Composition-based stats.
 Identities = 607/607 (100%), Positives = 607/607 (100%)

Query: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60
           MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ
Sbjct: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60

Query: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120
           KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA
Sbjct: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120

Query: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180
           EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF
Sbjct: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180

Query: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240
           SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI
Sbjct: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240

Query: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300
           AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS
Sbjct: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300

Query: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360
           TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF
Sbjct: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360

Query: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420
           ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS
Sbjct: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420

Query: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480
           GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF
Sbjct: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480

Query: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540
           FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG
Sbjct: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540

Query: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600
           AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM
Sbjct: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600

Query: 601 FNELSHL 607
           FNELSHL
Sbjct: 601 FNELSHL 607
>pdb|1IAT|A Chain A, Crystal Structure Of Human Phosphoglucose
           IsomeraseNEUROLEUKINAUTOCRINE MOTILITY FACTORMATURATION
           Factor
          Length = 557

 Score = 1125 bits (2911), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/557 (56%), Positives = 416/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 3   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 60  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 120 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 180 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 295 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 355 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 414

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 415 IRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 474 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 533

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HD+STNGLIN   +
Sbjct: 534 VTSHDASTNGLINFIKQ 550
>ref|NP_000166.2| glucose phosphate isomerase [Homo sapiens]
 sp|P06744|G6PI_HUMAN Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI) (Neuroleukin)
           (NLK) (Sperm antigen 36) (SA-36)
 pdb|1IRI|A Chain A, Crystal Structure Of Human Autocrine Motility Factor
           Complexed With An Inhibitor
 pdb|1IRI|B Chain B, Crystal Structure Of Human Autocrine Motility Factor
           Complexed With An Inhibitor
 pdb|1IRI|C Chain C, Crystal Structure Of Human Autocrine Motility Factor
           Complexed With An Inhibitor
 pdb|1IRI|D Chain D, Crystal Structure Of Human Autocrine Motility Factor
           Complexed With An Inhibitor
 pdb|1JIQ|A Chain A, Crystal Structure Of Human Autocrine Motility Factor
 pdb|1JIQ|B Chain B, Crystal Structure Of Human Autocrine Motility Factor
 pdb|1JIQ|C Chain C, Crystal Structure Of Human Autocrine Motility Factor
 pdb|1JIQ|D Chain D, Crystal Structure Of Human Autocrine Motility Factor
 pdb|1NUH|A Chain A, The Crystal Structure Of Human Phosphoglucose Isomerase
           Complexed With 5-Phosphoarabinonate
 gb|AAH04982.1| Glucose phosphate isomerase [Homo sapiens]
 gb|AAP72966.1| glucose phosphate isomerase [Homo sapiens]
 gb|ABM83850.1| glucose phosphate isomerase [synthetic construct]
 gb|ABM87172.1| glucose phosphate isomerase [synthetic construct]
          Length = 558

 Score = 1125 bits (2911), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/557 (56%), Positives = 416/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HD+STNGLIN   +
Sbjct: 535 VTSHDASTNGLINFIKQ 551
>gb|AAP36518.1| Homo sapiens glucose phosphate isomerase [synthetic construct]
 gb|AAX28981.1| glucose phosphate isomerase [synthetic construct]
 gb|AAX28982.1| glucose phosphate isomerase [synthetic construct]
          Length = 559

 Score = 1125 bits (2911), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/557 (56%), Positives = 416/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HD+STNGLIN   +
Sbjct: 535 VTSHDASTNGLINFIKQ 551
>sp|Q4R591|G6PI_MACFA Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 dbj|BAE01734.1| unnamed protein product [Macaca fascicularis]
          Length = 558

 Score = 1125 bits (2911), Expect = 0.0,   Method: Composition-based stats.
 Identities = 319/557 (57%), Positives = 417/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++G    +++ F+AD +R   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHGSELNLRRLFDADKDRFNHFSLTLN---TNHGHILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSEGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLTQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMRGKSTDEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HD+STNGLIN   +
Sbjct: 535 VTSHDASTNGLINFIKQ 551
>ref|XP_001219077.1| glucose-6-phosphate isomerase, glycosomal [Trypanosoma brucei]
 emb|CAJ16590.1| glucose-6-phosphate isomerase, glycosomal [Trypanosoma brucei]
          Length = 607

 Score = 1124 bits (2908), Expect = 0.0,   Method: Composition-based stats.
 Identities = 603/607 (99%), Positives = 605/607 (99%)

Query: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60
           MS+YLDDLR+ LAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ
Sbjct: 1   MSNYLDDLRMHLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60

Query: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120
           KLYEQYGDEPIKKHFE DSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA
Sbjct: 61  KLYEQYGDEPIKKHFETDSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120

Query: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180
           EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF
Sbjct: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180

Query: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240
           SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI
Sbjct: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240

Query: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300
           AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS
Sbjct: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300

Query: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360
           TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF
Sbjct: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360

Query: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420
           ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS
Sbjct: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420

Query: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480
           GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF
Sbjct: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480

Query: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540
           FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG
Sbjct: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540

Query: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600
           AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM
Sbjct: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600

Query: 601 FNELSHL 607
           FNELSHL
Sbjct: 601 FNELSHL 607
>pdb|1JLH|A Chain A, Human Glucose-6-Phosphate Isomerase
 pdb|1JLH|B Chain B, Human Glucose-6-Phosphate Isomerase
 pdb|1JLH|C Chain C, Human Glucose-6-Phosphate Isomerase
 pdb|1JLH|D Chain D, Human Glucose-6-Phosphate Isomerase
          Length = 558

 Score = 1123 bits (2906), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/557 (56%), Positives = 416/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTEMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HD+STNGLIN   +
Sbjct: 535 VTSHDASTNGLINFIKQ 551
>pdb|2O2C|A Chain A, Crystal Structure Of Phosphoglucose Isomerase From T.
           Brucei Containing Glucose-6-Phosphate In The Active Site
 pdb|2O2C|B Chain B, Crystal Structure Of Phosphoglucose Isomerase From T.
           Brucei Containing Glucose-6-Phosphate In The Active Site
 pdb|2O2C|C Chain C, Crystal Structure Of Phosphoglucose Isomerase From T.
           Brucei Containing Glucose-6-Phosphate In The Active Site
 pdb|2O2D|A Chain A, Crystal Structure Of Phosphoglucose Isomerase From
           Trypanosoma Brucei Complexed With Citrate
 pdb|2O2D|B Chain B, Crystal Structure Of Phosphoglucose Isomerase From
           Trypanosoma Brucei Complexed With Citrate
 pdb|2O2D|C Chain C, Crystal Structure Of Phosphoglucose Isomerase From
           Trypanosoma Brucei Complexed With Citrate
          Length = 613

 Score = 1121 bits (2902), Expect = 0.0,   Method: Composition-based stats.
 Identities = 604/605 (99%), Positives = 604/605 (99%)

Query: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60
           MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ
Sbjct: 1   MSSYLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQ 60

Query: 61  KLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120
           KLYEQYGDEPIKKHFE DSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA
Sbjct: 61  KLYEQYGDEPIKKHFETDSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLA 120

Query: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180
           EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF
Sbjct: 121 EERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSF 180

Query: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240
           SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI
Sbjct: 181 SEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHI 240

Query: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300
           AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS
Sbjct: 241 AEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALS 300

Query: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360
           TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF
Sbjct: 301 TNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHF 360

Query: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420
           ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS
Sbjct: 361 ANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRS 420

Query: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480
           GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF
Sbjct: 421 GKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNF 480

Query: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540
           FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG
Sbjct: 481 FAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALG 540

Query: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600
           AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM
Sbjct: 541 AIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINM 600

Query: 601 FNELS 605
           FNELS
Sbjct: 601 FNELS 605
>gb|AAF22645.1|AF187554_1 sperm antigen-36 [Homo sapiens]
          Length = 558

 Score = 1121 bits (2901), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/557 (56%), Positives = 416/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEA+M GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILVANFLAQTEAVMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HD+STNGLIN   +
Sbjct: 535 VTSHDASTNGLINFIKQ 551
>gb|AAA36368.1| neuroleukin
 gb|AAB36062.1| glucose phosphate isomerase, GPI {EC 5.3.1.9} [Homo sapiens=human,
           leukocyte, Peptide, 558 aa]
          Length = 558

 Score = 1120 bits (2899), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/557 (56%), Positives = 415/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGI GSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIVGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HD+STNGLIN   +
Sbjct: 535 VTSHDASTNGLINFIKQ 551
>pdb|1N8T|A Chain A, The Crystal Structure Of Phosphoglucose Isomerase From
           Rabbit Muscle
 pdb|1N8T|B Chain B, The Crystal Structure Of Phosphoglucose Isomerase From
           Rabbit Muscle
          Length = 557

 Score = 1118 bits (2894), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/557 (57%), Positives = 415/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G    ++  F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 3   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 60  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 120 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 180 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAETAKDWFL-----LSAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 295 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 355 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 414

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 415 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 474 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 533

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 534 VTSHDSSTNGLINFIKQ 550
>ref|NP_001075538.1| phosphoglucose isomerase [Oryctolagus cuniculus]
 sp|Q9N1E2|G6PI_RABIT Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAF13713.2|AF199601_1 phosphoglucose isomerase [Oryctolagus cuniculus]
          Length = 558

 Score = 1118 bits (2894), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/557 (57%), Positives = 415/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G    ++  F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 181 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAETAKDWFL-----LSAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 535 VTSHDSSTNGLINFIKQ 551
>pdb|1DQR|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase, A
           Glycolytic Enzyme That Moonlights As Neuroleukin,
           Autocrine Motility Factor, And Differentiation Mediator
 pdb|1DQR|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase, A
           Glycolytic Enzyme That Moonlights As Neuroleukin,
           Autocrine Motility Factor, And Differentiation Mediator
 pdb|1KOJ|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With 5-Phospho-D-Arabinonohydroxamic Acid
 pdb|1KOJ|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With 5-Phospho-D-Arabinonohydroxamic Acid
          Length = 557

 Score = 1118 bits (2893), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/557 (57%), Positives = 415/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G    ++  F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 3   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 60  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 120 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 180 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAKTAKDWFL-----LSAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 295 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 355 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 414

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 415 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 474 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 533

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 534 VTSHDSSTNGLINFIKQ 550
>pdb|1G98|A Chain A, Crystal Structure Analysis Of Rabbit Phosphoglucose
           Isomerase Complexed With 5-Phosphoarabinonate, A
           Transition State Analogue
 pdb|1G98|B Chain B, Crystal Structure Analysis Of Rabbit Phosphoglucose
           Isomerase Complexed With 5-Phosphoarabinonate, A
           Transition State Analogue
 pdb|1HOX|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Fructose-6-Phosphate
 pdb|1HOX|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Fructose-6-Phosphate
 pdb|1HM5|A Chain A, Crystal Structure Analysis Of The Rabbit D-Glucose 6-
           Phosphate Isomerase (No Ligand Bound)
 pdb|1HM5|B Chain B, Crystal Structure Analysis Of The Rabbit D-Glucose 6-
           Phosphate Isomerase (No Ligand Bound)
 pdb|1XTB|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Sorbitol-6-Phosphate
 pdb|1XTB|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Sorbitol-6-Phosphate
 gb|AAF35988.1|AF222069_1 phosphoglucose isomerase [Oryctolagus cuniculus]
          Length = 558

 Score = 1118 bits (2893), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/557 (57%), Positives = 415/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G    ++  F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 181 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAKTAKDWFL-----LSAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 535 VTSHDSSTNGLINFIKQ 551
>sp|Q5R4E3|G6PI_PONPY Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 emb|CAH93373.1| hypothetical protein [Pongo abelii]
          Length = 558

 Score = 1115 bits (2886), Expect = 0.0,   Method: Composition-based stats.
 Identities = 313/557 (56%), Positives = 416/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++G    +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHGSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  ++NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDIINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E+++ I+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSVSIIASKTFTTQETITNAETAKEWFL-----QTAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHK+ ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKVLLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HD+STNGLIN   +
Sbjct: 535 VTSHDASTNGLINFIKQ 551
>ref|NP_997475.1| glucose phosphate isomerase [Rattus norvegicus]
 gb|AAH62005.1| Glucose phosphate isomerase [Rattus norvegicus]
          Length = 558

 Score = 1110 bits (2873), Expect = 0.0,   Method: Composition-based stats.
 Identities = 318/556 (57%), Positives = 417/556 (75%), Gaps = 12/556 (2%)

Query: 50  LTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L +       +  +++ FEAD ER   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTRNPEFQKLLEWHRANSANLKLRELFEADPERFNHFSLNLN---TNHGHILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N+TE+R VLH+ALRNRSNR I +DGKDVMP
Sbjct: 61  NKEVLHMLVDLAKSRGVEAARDNMFSGLKINSTEDRAVLHVALRNRSNRSIMMDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGKAI  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKAITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L +++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWFVSNIDGTHIAKTLANLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTDKVKEFGIDPKNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P ++N P+LLAL+G+WYINF+G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFMKTPLDKNAPVLLALLGIWYINFYGCETHAMLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDYQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKSP E R+EL+AAG +S E++  LLPHK F G RP+
Sbjct: 416 IRNGLHHKILLANFLAQTEALMKGKSPEEARKELQAAG-KSPEELEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSSA 534

Query: 587 VNNHDSSTNGLINMFN 602
           V +HDSSTNGLI    
Sbjct: 535 VTSHDSSTNGLIGFIK 550
>ref|NP_032181.1| glucose phosphate isomerase 1 [Mus musculus]
 gb|AAA39825.1| neuroleukin
 dbj|BAE41301.1| unnamed protein product [Mus musculus]
          Length = 558

 Score = 1110 bits (2871), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/557 (56%), Positives = 414/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L +       +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTEDRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+  +     +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAK-----D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLI+   +
Sbjct: 535 VTSHDSSTNGLISFIKQ 551
>sp|P06745|G6PI_MOUSE Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI) (Neuroleukin)
           (NLK)
 gb|AAH86640.1| Glucose phosphate isomerase 1 [Mus musculus]
 gb|AAH88995.1| Glucose phosphate isomerase 1 [Mus musculus]
 dbj|BAE27695.1| unnamed protein product [Mus musculus]
 dbj|BAE29481.1| unnamed protein product [Mus musculus]
 emb|CAM21756.1| glucose phosphate isomerase 1 [Mus musculus]
          Length = 558

 Score = 1109 bits (2870), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/557 (56%), Positives = 414/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L +       +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TENR VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+  +     +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAK-----D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLI+   +
Sbjct: 535 VTSHDSSTNGLISFIKQ 551
>pdb|2CVP|A Chain A, Crystal Structure Of Mouse Amf
 pdb|2CVP|B Chain B, Crystal Structure Of Mouse Amf
 pdb|2CXN|A Chain A, Crystal Structure Of Mouse Amf  PHOSPHATE COMPLEX
 pdb|2CXN|B Chain B, Crystal Structure Of Mouse Amf  PHOSPHATE COMPLEX
 pdb|2CXO|A Chain A, Crystal Structure Of Mouse Amf  E4P COMPLEX
 pdb|2CXO|B Chain B, Crystal Structure Of Mouse Amf  E4P COMPLEX
 pdb|2CXP|A Chain A, Crystal Structure Of Mouse Amf  A5P COMPLEX
 pdb|2CXP|B Chain B, Crystal Structure Of Mouse Amf  A5P COMPLEX
 pdb|2CXQ|A Chain A, Crystal Structure Of Mouse Amf  S6P COMPLEX
 pdb|2CXQ|B Chain B, Crystal Structure Of Mouse Amf  S6P COMPLEX
 pdb|2CXR|A Chain A, Crystal Structure Of Mouse Amf  6PG COMPLEX
 pdb|2CXR|B Chain B, Crystal Structure Of Mouse Amf  6PG COMPLEX
 pdb|2CXS|A Chain A, Crystal Structure Of Mouse Amf  F6P COMPLEX
 pdb|2CXS|B Chain B, Crystal Structure Of Mouse Amf  F6P COMPLEX
 pdb|2CXT|A Chain A, Crystal Structure Of Mouse Amf  F6P COMPLEX
 pdb|2CXT|B Chain B, Crystal Structure Of Mouse Amf  F6P COMPLEX
 pdb|2CXU|A Chain A, Crystal Structure Of Mouse Amf  M6P COMPLEX
 pdb|2CXU|B Chain B, Crystal Structure Of Mouse Amf  M6P COMPLEX
          Length = 557

 Score = 1109 bits (2869), Expect = 0.0,   Method: Composition-based stats.
 Identities = 314/557 (56%), Positives = 414/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L +       +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           + E+   L+ LA+ RG+     ++F G ++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  SKEVMQMLVELAKSRGVEAARDNMFSGSKINYTEDRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+  +     +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAK-----D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLI+   +
Sbjct: 535 VTSHDSSTNGLISFIKQ 551
>prf||1405328A phosphohexose isomerase
          Length = 558

 Score = 1106 bits (2863), Expect = 0.0,   Method: Composition-based stats.
 Identities = 314/557 (56%), Positives = 413/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L +       +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTEDRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+ +SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKNKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+  +     +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAK-----D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLI+   +
Sbjct: 535 VTSHDSSTNGLISFIKQ 551
>dbj|BAE23502.1| unnamed protein product [Mus musculus]
          Length = 558

 Score = 1106 bits (2862), Expect = 0.0,   Method: Composition-based stats.
 Identities = 317/557 (56%), Positives = 415/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L +       +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TENR VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+  +     +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAK-----D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+LVQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKILVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLI+   +
Sbjct: 535 VTSHDSSTNGLISFIKQ 551
>pdb|1U0E|A Chain A, Crystal Structure Of Mouse Phosphoglucose Isomerase
 pdb|1U0E|B Chain B, Crystal Structure Of Mouse Phosphoglucose Isomerase
 pdb|1U0F|A Chain A, Crystal Structure Of Mouse Phosphoglucose Isomerase In
           Complex With Glucose 6-Phosphate
 pdb|1U0F|B Chain B, Crystal Structure Of Mouse Phosphoglucose Isomerase In
           Complex With Glucose 6-Phosphate
 pdb|1U0G|A Chain A, Crystal Structure Of Mouse Phosphoglucose Isomerase In
           Complex With Erythrose 4-Phosphate
 pdb|1U0G|B Chain B, Crystal Structure Of Mouse Phosphoglucose Isomerase In
           Complex With Erythrose 4-Phosphate
          Length = 564

 Score = 1106 bits (2862), Expect = 0.0,   Method: Composition-based stats.
 Identities = 314/557 (56%), Positives = 413/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L +       +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTEDRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+  +     +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAK-----D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NM +FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMLEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLI+   +
Sbjct: 535 VTSHDSSTNGLISFIKQ 551
>dbj|BAE21866.1| unnamed protein product [Mus musculus]
          Length = 558

 Score = 1106 bits (2862), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/557 (56%), Positives = 413/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L +       +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TENR VLH+ALRNRSN PI VDGKDV P
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVKP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+  +     +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAK-----D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLI+   +
Sbjct: 535 VTSHDSSTNGLISFIKQ 551
>dbj|BAE22329.1| unnamed protein product [Mus musculus]
          Length = 558

 Score = 1106 bits (2862), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/557 (56%), Positives = 413/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L +       +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TENR VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGT IA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+  +     +
Sbjct: 181 VWFVSNIDGTRIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAK-----D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLI+   +
Sbjct: 535 VTSHDSSTNGLISFIKQ 551
>dbj|BAE35416.1| unnamed protein product [Mus musculus]
          Length = 558

 Score = 1106 bits (2862), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/557 (56%), Positives = 413/557 (74%), Gaps = 12/557 (2%)

Query: 50  LTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L +       +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TENR VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+  +     +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAK-----D 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P  +N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLGKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLI+   +
Sbjct: 535 VTSHDSSTNGLISFIKQ 551
>sp|P50309|G6PI_CRIGR Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 emb|CAA86031.1| glucose phosphate isomerase [Cricetulus griseus]
          Length = 558

 Score = 1103 bits (2855), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/559 (56%), Positives = 410/559 (73%), Gaps = 12/559 (2%)

Query: 48  TTLTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
           T+LT    + +LQ    +   D  ++  F+AD ER   +S+ ++        + +DYSK+
Sbjct: 2   TSLTQNRYFQKLQDWHRDNSADINLRSLFDADPERFNNFSLNLN---TTHGHILVDYSKN 58

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            +N E+   L+ LA  RG+     ++F G ++N TE+R VLH+ALRNRSN PI VD +DV
Sbjct: 59  LVNKEVMQMLVDLARSRGVETMRDNMFSGVKINYTEDRAVLHVALRNRSNSPIVVDSRDV 118

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN+VL++MRSF ++VR+GEWKG++GK I  +VNIGIGGSDLGP+M TEALKP++   
Sbjct: 119 MPEVNRVLEKMRSFCQRVRSGEWKGYSGKPITDIVNIGIGGSDLGPLMVTEALKPYASGG 178

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
             + FVSN+DGTHIA+ L ++  E++LFIVASKTFTTQETITNA +A+   L        
Sbjct: 179 PRIWFVSNIDGTHIAKTLANLTPESSLFIVASKTFTTQETITNAETAKEWFL-----GAS 233

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            +  +VAKHF+ALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + IG++NF
Sbjct: 234 RDPSTVAKHFIALSTNTSKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHIGFDNF 293

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
            +LL+GAH +D+HF   P E+N P+LLAL+G+WYINF+G  THA+LPYDQY+ R  AY Q
Sbjct: 294 EQLLSGAHWMDQHFRKTPLEKNAPVLLALLGIWYINFYGCETHALLPYDQYMHRFAAYFQ 353

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q DMESNGK +TRSG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q
Sbjct: 354 QGDMESNGKSITRSGTRVDHHTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQ 413

Query: 467 NKI--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + I  G HHKI ++NF AQTEALM GKS  E ++EL+AAG +S E +  LLPHK F G R
Sbjct: 414 HPIRKGLHHKILLANFLAQTEALMKGKSNEEAKKELQAAG-KSPEDLEKLLPHKVFEGNR 472

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N+++   LTP  LGA+IA+YEHK+ VQG IW I+S+DQWGVELGK LAK+I P+L   
Sbjct: 473 PTNSIVFTKLTPFILGALIALYEHKIFVQGVIWDINSFDQWGVELGKQLAKNIEPELDGS 532

Query: 585 MRVNNHDSSTNGLINMFNE 603
             V +HDSSTNGLI    +
Sbjct: 533 APVTSHDSSTNGLIKFIKQ 551
>emb|CAC83783.1| phosphoglucose isomerase [Bufo melanostictus]
          Length = 553

 Score = 1101 bits (2848), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/559 (57%), Positives = 410/559 (73%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQ-YGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LTS   + +L K YE  +G   ++K FEAD ER  ++S  ++     E  + +DYSK+ I
Sbjct: 3   LTSDPVYQKLAKFYEANHGCLNLRKLFEADKERFNKFSKTLN---TGEGDILVDYSKNLI 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   L+ LA  RG+    + +F  E++N TENR VLHIALRNRSN PI VDGKD+MP
Sbjct: 60  TEEVIKLLIELARSRGVEAARKRMFSAEKINFTENRAVLHIALRNRSNAPIQVDGKDMMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN VL +M++F +KVR+G+WKG++GKAI  VVN+GIGGSDLGP+M TEALKP+S+    
Sbjct: 120 EVNAVLGKMKTFCQKVRSGDWKGYSGKAITDVVNVGIGGSDLGPLMVTEALKPYSKGGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTH+A+ L  ++ E TLFIVASKTFTTQETITNA +A+   L     +   +
Sbjct: 180 VWFVSNIDGTHMAKTLAELNPETTLFIVASKTFTTQETITNAETAKEWFL-----KAAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVK+FGID  NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 PSAVAKHFVALSTNAPKVKDFGIDTANMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEK 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL GAH +D HF N P E N+P++LA++GVWYINF+G  T A+LPYDQY+ R  AY QQ 
Sbjct: 295 LLAGAHWMDNHFCNTPLENNIPVILAMLGVWYINFYGCETQALLPYDQYMHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T++G  V+  TGP+++GE GTNGQHAFYQLIHQGT +IPCDF+   QSQN 
Sbjct: 355 DMESNGKYITKTGARVNYNTGPVVWGEPGTNGQHAFYQLIHQGTRMIPCDFMIPAQSQNP 414

Query: 469 IGD--HHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I D  HHKI M+NF AQTEALM GKS  E + EL+A+G  S E +  LLPHK F G RP+
Sbjct: 415 IRDGLHHKILMANFLAQTEALMKGKSTEEAKAELQASG-LSGEALEKLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   L+P  LGA+IAMYEHK+ VQG +W I+SYDQWGVELGK LAK I P+L     
Sbjct: 474 NSIVFGKLSPFILGALIAMYEHKIFVQGVVWDINSYDQWGVELGKQLAKKIEPELESNAP 533

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLIN +    
Sbjct: 534 VTSHDSSTNGLINFYKAHR 552
>dbj|BAF91562.1| phosphoglucose isomerase [Lepisosteus osseus]
          Length = 555

 Score = 1100 bits (2847), Expect = 0.0,   Method: Composition-based stats.
 Identities = 331/559 (59%), Positives = 417/559 (74%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQ-YGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LTS  S+ +L++ Y    G   +++ FEAD  R  ++S  ++    D+  + +D+SK+ I
Sbjct: 5   LTSDPSFQKLEQWYRANAGSLNMRQMFEADQGRFGKFSTTLN---TDDGDILVDFSKNLI 61

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N+E+   L  LA  RG+ +  + +F GE++N TENR VLHIALRNRSN PI+V GKDVMP
Sbjct: 62  NEEVMKMLFDLARSRGVEEAREKMFTGEKINFTENRAVLHIALRNRSNSPIHVGGKDVMP 121

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN VL++M++F +KVR+GEWKG+TGKAI  +VNIGIGGSDLGP+M TEALKP+S+    
Sbjct: 122 EVNSVLEKMKAFCQKVRSGEWKGYTGKAITDIVNIGIGGSDLGPLMVTEALKPYSKGGPR 181

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
             FVSN+DGTH+A+ L  ++ E TLFI+ASKTFTTQETITNA SA+  LL     +   +
Sbjct: 182 AWFVSNIDGTHMAKTLAELNPETTLFIIASKTFTTQETITNAESAKEWLL-----QKAGD 236

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
           K +VAKHFVALSTN  KVK+FGID  NMF+FWDWVGGRYS+WSAIGL I + IG+ENF  
Sbjct: 237 KSAVAKHFVALSTNAPKVKDFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALHIGFENFER 296

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D HF  AP E+NVP+LLAL+GVWYINFF A THA+LPYDQY+ R  AY QQ 
Sbjct: 297 LLSGAHWMDNHFRTAPLEKNVPVLLALLGVWYINFFQAETHALLPYDQYMHRFAAYFQQG 356

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T  G  V+  TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +QSQ+ 
Sbjct: 357 DMESNGKYITSKGSRVNYHTGPIVWGEPGTNGQHAFYQLIHQGTRMIPCDFLIPVQSQHP 416

Query: 469 IGD--HHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I +  HHKI ++NF AQTEALM GK+  E R+ELE AG  S E +  LLPHK F G +P+
Sbjct: 417 IRNNLHHKILLANFLAQTEALMKGKTTEEARKELEGAG-MSGEPLEKLLPHKVFEGNKPT 475

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++ K LTP  LGA+IAMYEHK+ +QG IW I+SYDQWGVELGK LAK I P+L+    
Sbjct: 476 NSIVFKKLTPFMLGALIAMYEHKIFMQGVIWEINSYDQWGVELGKQLAKKIEPELQDAGE 535

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HD STNGLI+   + S
Sbjct: 536 VTSHDGSTNGLISFIKKNS 554
>ref|XP_001490657.1| PREDICTED: similar to Glucose phosphate isomerase [Equus caballus]
          Length = 554

 Score = 1099 bits (2843), Expect = 0.0,   Method: Composition-based stats.
 Identities = 318/556 (57%), Positives = 409/556 (73%), Gaps = 16/556 (2%)

Query: 51  TSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHIN 109
           T    + +L++ + ++G +  +++HFE    R    ++       +   + +DYSK+ + 
Sbjct: 5   TQNPQFQKLREWHREHGAELNLRRHFE--RTRSAHLTLN-----TNHGHILVDYSKNLVT 57

Query: 110 DEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPA 169
           + +   L+ LA+ RG+    + +F GE++N TENR VLH+ALRNRSN PI VDGKDVMP 
Sbjct: 58  ESVMQMLVDLAKSRGVEAARERMFSGEKINFTENRAVLHVALRNRSNTPILVDGKDVMPE 117

Query: 170 VNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSL 229
           VNKVL++M+SF ++VR G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     +
Sbjct: 118 VNKVLEKMKSFCQQVRNGDWKGYTGKPITDVINIGIGGSDLGPLMVTEALKPYSSGGPRV 177

Query: 230 HFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEK 289
            FVSN+DGTHIA+ L S++ E+ LFI+ASKTFTTQETITNA +A+  LL         + 
Sbjct: 178 WFVSNIDGTHIAKTLASLNPESCLFIIASKTFTTQETITNAETAKEWLL-----LSAKDP 232

Query: 290 GSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVEL 349
            +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +L
Sbjct: 233 SAVAKHFVALSTNTTKVKEFGIDPKNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQL 292

Query: 350 LTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLD 409
           L+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  T A+LPYDQYL R  AY QQ D
Sbjct: 293 LSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETQAMLPYDQYLHRFAAYFQQGD 352

Query: 410 MESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKI 469
           MESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ I
Sbjct: 353 MESNGKYITKSGIRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPI 412

Query: 470 --GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSN 527
             G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E I  LLPHK F G RP+N
Sbjct: 413 RKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDIEKLLPHKVFEGNRPTN 471

Query: 528 TLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRV 587
           +++   LTP  LG++IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     V
Sbjct: 472 SIVFTKLTPFILGSLIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSAV 531

Query: 588 NNHDSSTNGLINMFNE 603
            +HDSSTNGLIN   +
Sbjct: 532 TSHDSSTNGLINFIKK 547
>ref|NP_001006128.1| glucose phosphate isomerase [Gallus gallus]
 emb|CAG30950.1| hypothetical protein [Gallus gallus]
          Length = 553

 Score = 1095 bits (2834), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/561 (57%), Positives = 409/561 (72%), Gaps = 12/561 (2%)

Query: 48  TTLTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
             L++   + +L + ++       +++ FEAD +R  ++S+ ++    D   + LDYSK+
Sbjct: 1   MPLSADPHFKKLLEWHKANASKLVLRQLFEADKDRFHKFSLTLN---TDHGDILLDYSKN 57

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            + +E+   L+ LA+ RG+    + +F GE++N TENR VLHIALRNRSN PI VDGKDV
Sbjct: 58  LVTEEVMKMLIELAKSRGVESARERMFSGEKINFTENRAVLHIALRNRSNTPILVDGKDV 117

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           +P VNKVLD+M+ F +KVR+GEWKG+TGKAI  VVNIGIGGSDLGP+M TE LKP+S+  
Sbjct: 118 VPEVNKVLDKMKHFCQKVRSGEWKGYTGKAITDVVNIGIGGSDLGPLMVTEVLKPYSKGG 177

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
             + FVSN+DGTHIA+ L  +  E TLFI+ASKTFTTQETITNA++A+   L        
Sbjct: 178 PRVWFVSNIDGTHIAKTLAELHPETTLFIIASKTFTTQETITNAVTAKEWFL-----HAA 232

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            +  +VAKHFVALSTN  KVKEFGID ENMF+FWDWVGGRYS+WSAIGL I + IG++NF
Sbjct: 233 KDPSAVAKHFVALSTNGPKVKEFGIDTENMFEFWDWVGGRYSLWSAIGLSIALHIGFDNF 292

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
             LL G H +D+HF  AP E+NVP+LLA++GVWYIN +G  THA+LPYDQY+ R  AY Q
Sbjct: 293 ESLLAGGHWMDKHFHTAPLEKNVPVLLAMLGVWYINCYGCETHALLPYDQYMHRFAAYFQ 352

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q DMESNGKY+T+ G  V   TGPI++GE  TNGQHAFYQLIHQGT +IPCDF+  +Q+Q
Sbjct: 353 QGDMESNGKYITKKGSRVDYNTGPIVWGEPDTNGQHAFYQLIHQGTRMIPCDFMIPVQTQ 412

Query: 467 NKI--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + +  G HHKI ++NF AQTEALM GK+  E R+EL+AAG  S + +  LLPHK F G R
Sbjct: 413 HPVRNGLHHKILLANFLAQTEALMKGKTADEARKELQAAG-LSGDALEKLLPHKVFEGNR 471

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N+++   L P  LGAIIAMYEHK+ VQG +W I+SYDQWGVELGK LAK I P+L   
Sbjct: 472 PTNSIMFTKLNPFTLGAIIAMYEHKIFVQGVVWDINSYDQWGVELGKQLAKKIEPELESD 531

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             V +HDSSTNGLI+   +  
Sbjct: 532 APVTSHDSSTNGLISFIKKHR 552
>gb|AAH83507.1| Glucose phosphate isomerase a [Danio rerio]
          Length = 553

 Score = 1095 bits (2832), Expect = 0.0,   Method: Composition-based stats.
 Identities = 325/560 (58%), Positives = 420/560 (75%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQ-YGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           L +  ++ +L++ Y+   G+  +++ FEAD++R  ++S+++   S D+  L LD+SK+ I
Sbjct: 3   LNNDPNFIKLEQWYKSSAGNLNMRQMFEADADRFNKFSLQL---STDDGDLLLDFSKNLI 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N+++   L  +A   G+    + +F GE++N TE R VLH ALRNRSN PI VDGKDVMP
Sbjct: 60  NEDVMSLLFDMARSVGVEAAREQMFAGEKINFTEGRAVLHTALRNRSNTPIMVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL+QM+SF  KVR+G WKG +GK+I  VVNIGIGGSDLGP+M TEALKP+S+   +
Sbjct: 120 EVNRVLEQMKSFCHKVRSGAWKGFSGKSITDVVNIGIGGSDLGPLMVTEALKPYSKGGPN 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTH+A+ L  ++ E TLFI+ASKTFTTQETITNA +AR   L     +   +
Sbjct: 180 VWFVSNIDGTHMAKTLAQLNAETTLFIIASKTFTTQETITNAETAREWFL-----QAAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
           K +VAKHFVALSTN  KVKEFGID  NMF+FWDWVGGRYS+WSAIGL I + IG++NF +
Sbjct: 235 KSAVAKHFVALSTNAPKVKEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALHIGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D HF +AP EQN P++LAL+GVWY+NFF A THA+LPYDQY+ R  AY QQ 
Sbjct: 295 LLSGAHWMDNHFRSAPLEQNAPVILALLGVWYVNFFQAETHALLPYDQYMHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V+  TGPI++GE GTNGQHAFYQLIHQGT LIP DF+   QSQ+ 
Sbjct: 355 DMESNGKYITKSGTRVNYHTGPIVWGEPGTNGQHAFYQLIHQGTRLIPADFLIPAQSQHP 414

Query: 469 IGD--HHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I D  HHKI M+NF AQTEALM GK+  E ++EL+A+G  S + +  LLPHK F G +PS
Sbjct: 415 IRDNLHHKILMANFLAQTEALMRGKTSDEAKKELQASG-LSGDSLEKLLPHKVFQGNKPS 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++ K LTP  LGA++AMYEHK+ VQG +W I+SYDQWGVELGK LAK I P+L+    
Sbjct: 474 NSIIFKKLTPFMLGALVAMYEHKIFVQGVMWNINSYDQWGVELGKQLAKKIEPELQDDAE 533

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V++HDSSTNGLI  F +   
Sbjct: 534 VHSHDSSTNGLIGFFKKNRS 553
>dbj|BAF91559.1| phosphoglucose isomerase [Polypterus ornatipinnis]
          Length = 556

 Score = 1094 bits (2830), Expect = 0.0,   Method: Composition-based stats.
 Identities = 326/563 (57%), Positives = 417/563 (74%), Gaps = 12/563 (2%)

Query: 46  ADTTLTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
           A   LTS  ++ +L++ Y+  G    +++ F++D +R +++S  +      +  + +DYS
Sbjct: 2   ASGGLTSDPNFQKLEQWYKANGAALNLRQLFDSDHDRFKKFSTTL---QTSDGDILIDYS 58

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I +E+   L+ LA+ RG+ +  + +F GE++N TENR VLHIALRNRSN PI V+GK
Sbjct: 59  KNLITEEVMKMLVELAKSRGVEKARERMFTGEKINFTENRAVLHIALRNRSNTPILVNGK 118

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL++M+ F +KVR+G+WKG+TGKAI  VVNIGIGGSDLGP+M TEALKP+S+
Sbjct: 119 DVMPEVNNVLEKMKKFCQKVRSGDWKGYTGKAITDVVNIGIGGSDLGPLMVTEALKPYSK 178

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
               + FVSN+DGTH+A+ L  ++ E TLFI+ASKTFTTQETITNA SA+   L     +
Sbjct: 179 GGPKVWFVSNIDGTHMAKTLAELNPETTLFIIASKTFTTQETITNAESAKEWFL-----Q 233

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              +K +VAKHFVALSTN  KVK+FGID  NMF+FWDWVGGRYS+WSAIGL I + IG+E
Sbjct: 234 AAVDKSAVAKHFVALSTNAPKVKDFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALHIGFE 293

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NF +LL+GAH +D HF N P ++NVP+LLAL+GVWYIN FGA THA+LPYDQY+ R  AY
Sbjct: 294 NFEQLLSGAHWMDNHFHNTPLDKNVPVLLALLGVWYINLFGAETHALLPYDQYMHRFAAY 353

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ DMESNGKY+T  G  V+  TGPI++GE GTNGQHAFYQLIHQGT ++P DF   +Q
Sbjct: 354 FQQGDMESNGKYITSQGTRVNYNTGPIVWGEPGTNGQHAFYQLIHQGTRMVPADFHIPVQ 413

Query: 465 SQNKIGD--HHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIG 522
           SQ+ I +  HHKI ++NF AQTEALM GK+  E R+ELE AG  S E +  LLPHK F G
Sbjct: 414 SQHPIRNNLHHKILLANFLAQTEALMKGKTSEEARKELEGAG-LSGEALEKLLPHKVFEG 472

Query: 523 GRPSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLR 582
            RP+N+++ K LTP  LGA+IAMYEHK+ VQG IW I+SYDQWGVELGK LAK I P+L 
Sbjct: 473 NRPTNSMVFKKLTPFILGALIAMYEHKIFVQGVIWDINSYDQWGVELGKQLAKKIEPELV 532

Query: 583 PGMRVNNHDSSTNGLINMFNELS 605
               V +HD STNGLI+   + S
Sbjct: 533 DASEVTSHDCSTNGLISFIKKNS 555
>ref|YP_001746414.1| glucose-6-phosphate isomerase [Escherichia coli SMS-3-5]
 gb|ACB18320.1| glucose-6-phosphate isomerase [Escherichia coli SMS-3-5]
          Length = 549

 Score = 1093 bits (2828), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/559 (56%), Positives = 407/559 (72%), Gaps = 13/559 (2%)

Query: 47  DTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
           +   T  A+W  LQK +++  D  I   F  D +R  ++SV        ++ + +DYSK+
Sbjct: 3   NINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSVTF------DDQMLVDYSKN 56

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGKDV
Sbjct: 57  RITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDV 116

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +  
Sbjct: 117 MPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-KNH 175

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
           L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +  
Sbjct: 176 LNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----KAA 230

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++NF
Sbjct: 231 GDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNF 290

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
           VELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY Q
Sbjct: 291 VELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQ 350

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    + 
Sbjct: 351 QGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITH 410

Query: 467 NKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G RP+
Sbjct: 411 NPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNRPT 469

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+    
Sbjct: 470 NSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKE 529

Query: 587 VNNHDSSTNGLINMFNELS 605
           +++HDSSTNGLIN +    
Sbjct: 530 ISSHDSSTNGLINRYKAWR 548
>ref|NP_001085765.1| MGC80718 protein [Xenopus laevis]
 gb|AAH73315.1| MGC80718 protein [Xenopus laevis]
          Length = 553

 Score = 1093 bits (2828), Expect = 0.0,   Method: Composition-based stats.
 Identities = 318/560 (56%), Positives = 409/560 (73%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYE-QYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L + YE  +    +++ FEAD +R  +YS  +     D+  + LDYSK+ I
Sbjct: 3   LTCDPVYQKLSQWYEAHHAGLNMRQMFEADKDRFSKYSKTL---VTDDGDILLDYSKNLI 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N+++   L+ LA  RG+    Q +F  E++N TENR VLHIALRNRSN PI +DGKDVMP
Sbjct: 60  NEDVLKLLIELARSRGVESARQKMFSAEKINFTENRAVLHIALRNRSNTPIPLDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN VL++M++F +KVR+G+WKG+ GKAI  VVNIGIGGSDLGP+M TE+LKP+S+    
Sbjct: 120 EVNAVLEKMKAFCQKVRSGDWKGYNGKAITDVVNIGIGGSDLGPLMVTESLKPYSKGGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E TLFI+ASKTFTTQETITNA +AR   L+        +
Sbjct: 180 VWFVSNIDGTHIAKTLAELNPETTLFIIASKTFTTQETITNAETAREWFLN-----SAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVK+FGID  NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 ASAVAKHFVALSTNAPKVKDFGIDTANMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEK 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL GAH +D HF   P E NVP++LA++G+WYINF+G  THA+LPYDQY+ R  AY QQ 
Sbjct: 295 LLAGAHWMDNHFYKTPLENNVPVILAMLGIWYINFYGCETHALLPYDQYMHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T++G  V+  TGP+++GE GTNGQHAFYQLIHQGT  IPCDF+  +Q+QN 
Sbjct: 355 DMESNGKYITKTGARVNYNTGPVVWGEPGTNGQHAFYQLIHQGTRKIPCDFLIPVQTQNP 414

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI +SNF AQTEALM GKS  E ++EL+A+G  + E ++ LLPHK F G RP+
Sbjct: 415 IRNGLHHKILLSNFLAQTEALMKGKSTDEAKKELQASG-LTGEALDKLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   L P  LGA+IAMYEHK+ VQG +W I+SYDQWGVELGK LAK I P+L     
Sbjct: 474 NSIVFTKLNPFILGALIAMYEHKIFVQGVVWDINSYDQWGVELGKQLAKKIEPELESDAT 533

Query: 587 VNNHDSSTNGLINMFNELSH 606
           + +HD STNGLIN   +   
Sbjct: 534 ITSHDGSTNGLINFIKKHRS 553
>ref|ZP_00724931.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli F11]
 ref|YP_672094.1| glucose-6-phosphate isomerase [Escherichia coli 536]
 ref|YP_859617.1| glucose-6-phosphate isomerase [Escherichia coli APEC O1]
 ref|NP_756843.2| glucose-6-phosphate isomerase [Escherichia coli CFT073]
 sp|Q8FB44|G6PI_ECOL6 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|A1AIK3|G6PI_ECOK1 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q0TA36|G6PI_ECOL5 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q1R3R3|G6PI_ECOUT Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|ABG72193.1| glucose-6-phosphate isomerase [Escherichia coli 536]
 gb|ABJ03493.1| glucose-6-phosphate isomerase [Escherichia coli APEC O1]
          Length = 549

 Score = 1093 bits (2827), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/559 (56%), Positives = 407/559 (72%), Gaps = 13/559 (2%)

Query: 47  DTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
           +   T  A+W  LQK +++  D  I   F  D +R  ++S         ++ + +DYSK+
Sbjct: 3   NINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATF------DDQMLVDYSKN 56

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGKDV
Sbjct: 57  RITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDV 116

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +  
Sbjct: 117 MPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-KNH 175

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
           L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +  
Sbjct: 176 LNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----KAA 230

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++NF
Sbjct: 231 GDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNF 290

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
           VELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY Q
Sbjct: 291 VELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQ 350

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q +MESNGKYV R+GK V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    + 
Sbjct: 351 QGNMESNGKYVDRNGKVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITH 410

Query: 467 NKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G RP+
Sbjct: 411 NPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNRPT 469

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+    
Sbjct: 470 NSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKE 529

Query: 587 VNNHDSSTNGLINMFNELS 605
           +++HDSSTNGLIN +    
Sbjct: 530 ISSHDSSTNGLINRYKAWR 548
>ref|YP_543532.1| glucose-6-phosphate isomerase [Escherichia coli UTI89]
 gb|AAN83417.1|AE016770_217 Glucose-6-phosphate isomerase [Escherichia coli CFT073]
 gb|ABE10001.1| glucose-6-phosphate isomerase [Escherichia coli UTI89]
          Length = 551

 Score = 1093 bits (2827), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/559 (56%), Positives = 407/559 (72%), Gaps = 13/559 (2%)

Query: 47  DTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
           +   T  A+W  LQK +++  D  I   F  D +R  ++S         ++ + +DYSK+
Sbjct: 5   NINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATF------DDQMLVDYSKN 58

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGKDV
Sbjct: 59  RITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDV 118

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +  
Sbjct: 119 MPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-KNH 177

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
           L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +  
Sbjct: 178 LNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----KAA 232

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++NF
Sbjct: 233 GDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNF 292

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
           VELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY Q
Sbjct: 293 VELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQ 352

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q +MESNGKYV R+GK V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    + 
Sbjct: 353 QGNMESNGKYVDRNGKVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITH 412

Query: 467 NKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G RP+
Sbjct: 413 NPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNRPT 471

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+    
Sbjct: 472 NSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKE 531

Query: 587 VNNHDSSTNGLINMFNELS 605
           +++HDSSTNGLIN +    
Sbjct: 532 ISSHDSSTNGLINRYKAWR 550
>dbj|BAF91563.1| phosphoglucose isomerase [Acipenser ruthenus]
          Length = 555

 Score = 1093 bits (2827), Expect = 0.0,   Method: Composition-based stats.
 Identities = 326/560 (58%), Positives = 412/560 (73%), Gaps = 12/560 (2%)

Query: 48  TTLTSCASWTQLQKLY-EQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
           + LTS  ++ +LQ+ + ++     +++ F+AD +R  + S  +     D+  + +DYSK+
Sbjct: 3   SGLTSDPNFQKLQQWHKDKAASLKMRQMFQADKDRFNKLSTTL---KTDDGDILIDYSKN 59

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            I +E+   L+ LA+ RG+ Q  + +F GE++N TE R VLHIALRNRSN PI V GKDV
Sbjct: 60  LITEEVMKMLVDLAKSRGVEQAREKMFTGEQINFTEGRAVLHIALRNRSNSPINVAGKDV 119

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VNKVL++M++F +KVR+G+WKG+TGK+I  VVNIGIGGSDLGP+M TEALKP+S+  
Sbjct: 120 MPEVNKVLEKMKNFCQKVRSGDWKGYTGKSITDVVNIGIGGSDLGPLMVTEALKPYSKGG 179

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
               FVSN+DGTH+A+ L  ++ E TLFI+ASKTFTTQETITNA SA+   L     +  
Sbjct: 180 PKAWFVSNIDGTHMAKTLAELNPETTLFIIASKTFTTQETITNAESAKEWFL-----QSA 234

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            +K +VAKHFVALSTN  KVK+FGID  NMF+FWDWVGGRYS+WSAIGL I + IG+ENF
Sbjct: 235 GDKSAVAKHFVALSTNAPKVKDFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALHIGFENF 294

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
             LL+GAH +D HF N P ++NVP+LLAL+GVWY N FGA THA+LPYDQY+ R  AY Q
Sbjct: 295 EHLLSGAHWMDNHFRNTPLDKNVPVLLALLGVWYGNMFGAETHALLPYDQYMHRFAAYFQ 354

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q DMESNGKY+T  G  V   TGPI++GE GTNGQHAFYQLIHQGT +IP DF   +Q+Q
Sbjct: 355 QGDMESNGKYITSKGTRVDYSTGPIVWGEPGTNGQHAFYQLIHQGTRMIPADFHIPVQTQ 414

Query: 467 NKIGD--HHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           N I +  HHKI M+NF AQTEALM GK+  E R+ELE AG  S E +  LLPHK F G +
Sbjct: 415 NPIRNNLHHKILMANFLAQTEALMKGKTTEEARKELEGAG-LSGEALENLLPHKVFEGNK 473

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N+++ K LTP  LGA+IAMYEHK+ VQG IW I+SYDQWGVELGK LAK I P+L+  
Sbjct: 474 PTNSIVFKKLTPFILGALIAMYEHKIFVQGVIWDINSYDQWGVELGKQLAKQIEPELQDN 533

Query: 585 MRVNNHDSSTNGLINMFNEL 604
             V +HD STNGLIN   + 
Sbjct: 534 SEVTSHDCSTNGLINFIKKN 553
>ref|NP_290659.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 EDL933]
 ref|NP_313035.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str. Sakai]
 ref|NP_418449.1| glucosephosphate isomerase [Escherichia coli str. K-12 substr.
           MG1655]
 ref|YP_312937.1| glucose-6-phosphate isomerase [Shigella sonnei Ss046]
 ref|YP_410315.1| glucose-6-phosphate isomerase [Shigella boydii Sb227]
 ref|YP_405619.1| glucose-6-phosphate isomerase [Shigella dysenteriae Sd197]
 ref|ZP_00925748.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli 101-1]
 ref|AP_004526.1| glucosephosphate isomerase [Escherichia coli W3110]
 ref|ZP_02739575.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4045]
 ref|ZP_02751760.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4206]
 ref|ZP_02769327.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4115]
 ref|ZP_02775869.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4113]
 ref|ZP_02780180.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4401]
 ref|ZP_02785875.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4501]
 ref|ZP_02791270.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4486]
 ref|ZP_02799367.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4196]
 ref|ZP_02805422.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4076]
 ref|ZP_02809625.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str. EC869]
 ref|ZP_02819451.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4042]
 ref|ZP_02823342.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str. EC508]
 ref|YP_001726931.1| Glucose-6-phosphate isomerase [Escherichia coli ATCC 8739]
 ref|YP_001732802.1| glucosephosphate isomerase [Escherichia coli str. K-12 substr.
           DH10B]
 ref|YP_001882711.1| glucose-6-phosphate isomerase [Shigella boydii CDC 3083-94]
 ref|ZP_02999367.1| glucose-6-phosphate isomerase [Escherichia coli 53638]
 sp|P0A6T1|G6PI_ECOLI Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|P0A6T2|G6PI_ECO57 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q31TX1|G6PI_SHIBS Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q328X7|G6PI_SHIDS Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q3YUW0|G6PI_SHISS Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAG59224.1|AE005635_4 glucosephosphate isomerase [Escherichia coli O157:H7 EDL933]
 gb|AAC43119.1| glucose-6-phosphate isomerase [Escherichia coli]
 gb|AAC76995.1| glucosephosphate isomerase [Escherichia coli str. K-12 substr.
           MG1655]
 dbj|BAB38431.1| glucosephosphate isomerase [Escherichia coli O157:H7 str. Sakai]
 gb|AAZ90702.1| glucosephosphate isomerase [Shigella sonnei Ss046]
 gb|ABB64128.1| glucosephosphate isomerase [Shigella dysenteriae Sd197]
 gb|ABB68487.1| glucosephosphate isomerase [Shigella boydii Sb227]
 dbj|BAE78027.1| glucosephosphate isomerase [Escherichia coli W3110]
 gb|ACA79604.1| Glucose-6-phosphate isomerase [Escherichia coli ATCC 8739]
 gb|ACB05024.1| glucosephosphate isomerase [Escherichia coli str. K-12 substr.
           DH10B]
 gb|ACD08826.1| glucose-6-phosphate isomerase [Shigella boydii CDC 3083-94]
 gb|EDU33726.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4196]
 gb|EDU53151.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4113]
 gb|EDU62399.1| glucose-6-phosphate isomerase [Escherichia coli 53638]
 gb|EDU70767.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4076]
          Length = 549

 Score = 1092 bits (2826), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/559 (56%), Positives = 406/559 (72%), Gaps = 13/559 (2%)

Query: 47  DTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
           +   T  A+W  LQK +++  D  I   F  D +R  ++S         ++ + +DYSK+
Sbjct: 3   NINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATF------DDQMLVDYSKN 56

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGKDV
Sbjct: 57  RITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDV 116

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +  
Sbjct: 117 MPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-KNH 175

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
           L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +  
Sbjct: 176 LNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----KAA 230

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++NF
Sbjct: 231 GDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNF 290

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
           VELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY Q
Sbjct: 291 VELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQ 350

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    + 
Sbjct: 351 QGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITH 410

Query: 467 NKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G RP+
Sbjct: 411 NPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNRPT 469

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+    
Sbjct: 470 NSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKE 529

Query: 587 VNNHDSSTNGLINMFNELS 605
           +++HDSSTNGLIN +    
Sbjct: 530 ISSHDSSTNGLINRYKAWR 548
>ref|ZP_00711964.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli B171]
 ref|ZP_00715960.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli B7A]
 ref|ZP_00722553.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli E110019]
 ref|ZP_00730314.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli E22]
 ref|YP_001465522.1| glucose-6-phosphate isomerase [Escherichia coli E24377A]
 ref|YP_001460811.1| glucose-6-phosphate isomerase [Escherichia coli HS]
 sp|A7ZUP3|G6PI_ECO24 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|A8A7C4|G6PI_ECOHS Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|ABV08428.1| glucose-6-phosphate isomerase [Escherichia coli HS]
 gb|ABV16980.1| glucose-6-phosphate isomerase [Escherichia coli E24377A]
          Length = 549

 Score = 1092 bits (2825), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/559 (56%), Positives = 405/559 (72%), Gaps = 13/559 (2%)

Query: 47  DTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
           +   T  A+W  LQK +++  D  I   F  D +R  ++S          + + +DYSK+
Sbjct: 3   NINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFG------DQMLVDYSKN 56

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGKDV
Sbjct: 57  RITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDV 116

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +  
Sbjct: 117 MPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-KNH 175

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
           L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +  
Sbjct: 176 LNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----KAA 230

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++NF
Sbjct: 231 GDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNF 290

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
           VELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY Q
Sbjct: 291 VELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQ 350

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    + 
Sbjct: 351 QGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITH 410

Query: 467 NKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G RP+
Sbjct: 411 NPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNRPT 469

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+    
Sbjct: 470 NSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKE 529

Query: 587 VNNHDSSTNGLINMFNELS 605
           +++HDSSTNGLIN +    
Sbjct: 530 ISSHDSSTNGLINRYKAWR 548
>dbj|BAF91556.1| phosphoglucose isomerase [Amia calva]
          Length = 555

 Score = 1091 bits (2824), Expect = 0.0,   Method: Composition-based stats.
 Identities = 328/559 (58%), Positives = 411/559 (73%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQ-YGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LTS  S+ +L+K Y+   G+  +++ F+AD +R  ++S  +     DE  L +DYSK+ I
Sbjct: 5   LTSDPSYKKLEKWYKSNAGNLNMRQMFDADKQRFSKFSTTL---KTDEGDLLIDYSKNLI 61

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   L  +A+ RG+ +  + +F+GE++N TE R VLHIALRNRSN PI VDGKDVMP
Sbjct: 62  TEEVLKMLYEMAKSRGVLEARERMFKGEKINFTEGRAVLHIALRNRSNSPIEVDGKDVMP 121

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN VL++M+ F +KVR+G+WKG++GK I  V+NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 122 DVNNVLEKMKGFCQKVRSGDWKGYSGKPITDVINIGIGGSDLGPLMVTEALKPYSKGGPR 181

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTH+A+ L  +D E +LFI+ASKTFTTQETITNA SA+   L     +   +
Sbjct: 182 VWFVSNIDGTHMAKTLAELDPETSLFIIASKTFTTQETITNAESAKEWFL-----QKAGD 236

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID  NMF+FWDWVGGRYS+WSAIGL I + IG+ENF +
Sbjct: 237 ASAVAKHFVALSTNAPKVKEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALHIGFENFEK 296

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D HF  AP EQNVP+LLAL+GVWYINFF A TH +LPYDQY+ R  AY QQ 
Sbjct: 297 LLSGAHWMDNHFRTAPLEQNVPILLALLGVWYINFFQAETHVMLPYDQYMHRFAAYFQQG 356

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T  G  V+  TGPI++GE GTNGQHAFYQLIHQGT +IP DF+   QSQN 
Sbjct: 357 DMESNGKYITSKGDRVNYHTGPIVWGEPGTNGQHAFYQLIHQGTRMIPADFLIPAQSQNP 416

Query: 469 IGD--HHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I    HHKI ++NF AQTEALM GKS  E ++ELE AG  S E +  LLPHK F G +P+
Sbjct: 417 IRSNLHHKILLANFLAQTEALMKGKSSDEAQKELEGAG-MSGEALEKLLPHKVFQGNKPT 475

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   L P  LGA+IAMYEHK+ VQG IW I+SYDQWGVELGK LAK I P+L+    
Sbjct: 476 NSMVFTKLNPFMLGALIAMYEHKIFVQGVIWDINSYDQWGVELGKQLAKKIEPELQDASE 535

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLI    + S
Sbjct: 536 VTSHDSSTNGLIGFIKKNS 554
>ref|XP_820895.1| glucose-6-phosphate isomerase, glycosomal, putative [Trypanosoma
           cruzi strain CL Brener]
 gb|EAN99044.1| glucose-6-phosphate isomerase, glycosomal, putative [Trypanosoma
           cruzi]
          Length = 608

 Score = 1091 bits (2824), Expect = 0.0,   Method: Composition-based stats.
 Identities = 447/604 (74%), Positives = 524/604 (86%)

Query: 4   YLDDLRIDLAASPASGGSASIAVGSFNIPYEVTRRLKGVGADADTTLTSCASWTQLQKLY 63
           YL DL + L  S A+  + S+AV SFN+P+E+TRR++ +G D DT+L+SC SW +LQ+LY
Sbjct: 5   YLKDLTVHLNESNAAPANTSMAVASFNMPHEITRRMRPLGVDTDTSLSSCPSWRRLQELY 64

Query: 64  EQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHINDEIKCALLRLAEER 123
           E +G E I K+F+   +R QRYS++V L S D+NF+FLDYSK+HINDEIK  L +L EER
Sbjct: 65  EIHGSESILKNFDECKDRFQRYSLEVDLRSSDKNFVFLDYSKTHINDEIKDVLFKLVEER 124

Query: 124 GIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPAVNKVLDQMRSFSEK 183
           GIR F++++F GE+VNT ENR VLHIALRNRSNRPI+VDG DVMP VNKVL+QM+  SEK
Sbjct: 125 GIRAFMRALFAGEKVNTAENRSVLHIALRNRSNRPIFVDGHDVMPMVNKVLEQMKKISEK 184

Query: 184 VRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSLHFVSNVDGTHIAEV 243
           VR GEWKG +GK IRHVVNIGIGGSDLGP+MA EALKPFS R +S+HFVSN+DGTH++EV
Sbjct: 185 VRRGEWKGQSGKPIRHVVNIGIGGSDLGPMMACEALKPFSDRRISMHFVSNIDGTHLSEV 244

Query: 244 LKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEKGSVAKHFVALSTNN 303
           LK +D+E+TLFI+ASKTFTTQETITNALSAR   L +L SRGI E G+VAKHFVALSTN 
Sbjct: 245 LKLVDLESTLFIIASKTFTTQETITNALSARSEFLKFLSSRGIPEAGAVAKHFVALSTNA 304

Query: 304 QKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVELLTGAHVIDEHFANA 363
           +KVKEFGIDE NMFQFWDWVGGRYS+WSAIGL +MISIGY+NFVE LTGAH++DEHF NA
Sbjct: 305 EKVKEFGIDEANMFQFWDWVGGRYSLWSAIGLSVMISIGYDNFVEFLTGAHIMDEHFINA 364

Query: 364 PPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLDMESNGKYVTRSGKT 423
           P E N+P++LALVG+WY NFFG+ T AILPYDQYLWRLPAYLQQLDMESNGK  T++G+ 
Sbjct: 365 PTENNLPIILALVGIWYNNFFGSETQAILPYDQYLWRLPAYLQQLDMESNGKGATKNGRM 424

Query: 424 VSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKIGDHHKIFMSNFFAQ 483
           VST TGPIIFGEAGTNGQHAFYQLIHQGT LIPCDFIGAIQ+QN IG+HH+I MSNFFAQ
Sbjct: 425 VSTHTGPIIFGEAGTNGQHAFYQLIHQGTKLIPCDFIGAIQTQNYIGEHHRILMSNFFAQ 484

Query: 484 TEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSNTLLIKSLTPRALGAII 543
           TEALMIGK+P EV+RELE+AG +S ++I  L+P KTF GGRPSN+LL+K+LTPRALGAII
Sbjct: 485 TEALMIGKTPEEVKRELESAGGKSEDEIQLLIPQKTFTGGRPSNSLLVKALTPRALGAII 544

Query: 544 AMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRVNNHDSSTNGLINMFNE 603
           AMYEHKVLVQGAIWGI+SYDQWGVELGK+LAKSILPQL+PG +V NHDSSTNGLI +FNE
Sbjct: 545 AMYEHKVLVQGAIWGINSYDQWGVELGKLLAKSILPQLQPGQKVTNHDSSTNGLIKLFNE 604

Query: 604 LSHL 607
            SHL
Sbjct: 605 RSHL 608
>gb|AAH44450.1| Glucose phosphate isomerase a [Danio rerio]
          Length = 553

 Score = 1091 bits (2824), Expect = 0.0,   Method: Composition-based stats.
 Identities = 324/560 (57%), Positives = 419/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQ-YGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           L +  ++ +L++ Y+   G+  +++ FEAD++R  ++S+++   S D+  L LD+SK+ I
Sbjct: 3   LNNDPNFIKLEQWYKSSAGNLNMRQMFEADADRFNKFSLQL---STDDGDLLLDFSKNLI 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N+++   L  +A   G+    + +F GE++N TE R VLH ALRNRSN PI VDGKDVMP
Sbjct: 60  NEDVMSLLFDMARSVGVEAAREQMFAGEKINFTEGRAVLHTALRNRSNTPIMVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL+QM+SF  KVR+  WKG +GK+I  VVNIGIGGSDLGP+M TEALKP+S+   +
Sbjct: 120 EVNRVLEQMKSFCHKVRSSAWKGFSGKSITDVVNIGIGGSDLGPLMVTEALKPYSKGGPN 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTH+A+ L  ++ E TLFI+ASKTFTTQETITNA +AR   L     +   +
Sbjct: 180 VWFVSNIDGTHMAKTLAQLNAETTLFIIASKTFTTQETITNAETAREWFL-----QAAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
           K +VAKHFVALSTN  KVKEFGID  NMF+FWDWVGGRYS+WSAIGL I + IG++NF +
Sbjct: 235 KSAVAKHFVALSTNAPKVKEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALHIGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D HF +AP EQN P++LAL+GVWY+NFF A THA+LPYDQY+ R  AY QQ 
Sbjct: 295 LLSGAHWMDNHFRSAPLEQNAPVILALLGVWYVNFFQAETHALLPYDQYMHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V+  TGPI++GE GTNGQHAFYQLIHQGT LIP DF+   QSQ+ 
Sbjct: 355 DMESNGKYITKSGTRVNYHTGPIVWGEPGTNGQHAFYQLIHQGTRLIPADFLIPAQSQHP 414

Query: 469 IGD--HHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I D  HHKI M+NF AQTEALM GK+  E ++EL+A+G  S + +  LLPHK F G +PS
Sbjct: 415 IRDNLHHKILMANFLAQTEALMRGKTSDEAKKELQASG-LSGDSLEKLLPHKVFQGNKPS 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++ K LTP  LGA++AMYEHK+ VQG +W I+SYDQWGVELGK LAK I P+L+    
Sbjct: 474 NSIIFKKLTPFMLGALVAMYEHKIFVQGVMWNINSYDQWGVELGKQLAKKIEPELQDDAE 533

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V++HDSSTNGLI  F +   
Sbjct: 534 VHSHDSSTNGLIGFFKKNRS 553
>ref|XP_867955.1| PREDICTED: similar to Glucose-6-phosphate isomerase (GPI)
           (Phosphoglucose isomerase) (PGI) (Phosphohexose
           isomerase) (PHI) (Neuroleukin) (NLK) (Sperm antigen-36)
           (SA-36) isoform 2 [Canis familiaris]
          Length = 543

 Score = 1091 bits (2824), Expect = 0.0,   Method: Composition-based stats.
 Identities = 309/557 (55%), Positives = 401/557 (71%), Gaps = 27/557 (4%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQK + + G D  +++ FE D ER  R+S+ ++    +   + +DYSK+ +
Sbjct: 4   LTQSPQFQKLQKWHREQGSDLNLRRLFEGDKERFNRFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            D +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TDTVMQMLVDLAKSRGVEAARERMFSGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNRVLEKMKSFCQRVRSGEWKGYSGKPITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHI++ L +++ E++LFI+ASK                  L         +
Sbjct: 181 VWFVSNIDGTHISKTLAALNPESSLFIIASK---------------EWFL-----LSAKD 220

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 221 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 280

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 281 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETQAMLPYDQYLHRFAAYFQQG 340

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 341 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 400

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 401 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 459

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 460 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 519

Query: 587 VNNHDSSTNGLINMFNE 603
           V +HDSSTNGLIN   +
Sbjct: 520 VTSHDSSTNGLINFIKQ 536
>ref|NP_838787.1| glucose-6-phosphate isomerase [Shigella flexneri 2a str. 2457T]
 ref|NP_709894.2| glucose-6-phosphate isomerase [Shigella flexneri 2a str. 301]
 sp|Q83IN9|G6PI_SHIFL Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAP18598.1| glucosephosphate isomerase [Shigella flexneri 2a str. 2457T]
 gb|AAN45601.2| glucosephosphate isomerase [Shigella flexneri 2a str. 301]
          Length = 549

 Score = 1091 bits (2824), Expect = 0.0,   Method: Composition-based stats.
 Identities = 314/559 (56%), Positives = 406/559 (72%), Gaps = 13/559 (2%)

Query: 47  DTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
           +   T  A+W  LQK +++  D  I   F  D +R  ++S         ++ + +DYSK+
Sbjct: 3   NINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATF------DDQMLVDYSKN 56

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGKDV
Sbjct: 57  RITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDV 116

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +  
Sbjct: 117 MPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-KNH 175

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
           L++HFVSNVDGTHI+EVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +  
Sbjct: 176 LNMHFVSNVDGTHISEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----KAA 230

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++NF
Sbjct: 231 GDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNF 290

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
           VELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY Q
Sbjct: 291 VELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQ 350

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    + 
Sbjct: 351 QGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITH 410

Query: 467 NKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G RP+
Sbjct: 411 NPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNRPT 469

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+    
Sbjct: 470 NSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKE 529

Query: 587 VNNHDSSTNGLINMFNELS 605
           +++HDSSTNGLIN +    
Sbjct: 530 ISSHDSSTNGLINRYKAWR 548
Searching..................................................done Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|XP_867960.1|  PREDICTED: similar to Glucose-6-phosphate ...  1133   0.0  
ref|XP_853858.1|  PREDICTED: similar to Glucose-6-phosphate ...  1131   0.0  
ref|NP_999495.1|  glucose phosphate isomerase [Sus scrofa] >...  1130   0.0  
pdb|1GZD|A  Chain A, Crystal Structure Of Pig Phosphoglucose...  1130   0.0  
ref|XP_867967.1|  PREDICTED: similar to Glucose-6-phosphate ...  1125   0.0  
ref|NP_001035561.1|  glucose phosphate isomerase [Bos taurus...  1124   0.0  
sp|Q4R591|G6PI_MACFA  Glucose-6-phosphate isomerase (GPI) (P...  1120   0.0  
pdb|1IAT|A  Chain A, Crystal Structure Of Human Phosphogluco...  1120   0.0  
ref|NP_000166.2|  glucose phosphate isomerase [Homo sapiens]...  1120   0.0  
gb|AAP36518.1|  Homo sapiens glucose phosphate isomerase [sy...  1120   0.0  
pdb|1JLH|A  Chain A, Human Glucose-6-Phosphate Isomerase >gi...  1118   0.0  
gb|AAF22645.1|AF187554_1  sperm antigen-36 [Homo sapiens]        1117   0.0  
gb|AAA36368.1|  neuroleukin >gi|1336765|gb|AAB36062.1| gluco...  1116   0.0  
pdb|1N8T|A  Chain A, The Crystal Structure Of Phosphoglucose...  1115   0.0  
ref|NP_001075538.1|  phosphoglucose isomerase [Oryctolagus c...  1115   0.0  
pdb|1DQR|A  Chain A, Crystal Structure Of Rabbit Phosphogluc...  1115   0.0  
pdb|1G98|A  Chain A, Crystal Structure Analysis Of Rabbit Ph...  1115   0.0  
sp|Q5R4E3|G6PI_PONPY  Glucose-6-phosphate isomerase (GPI) (P...  1111   0.0  
ref|YP_001746414.1|  glucose-6-phosphate isomerase [Escheric...  1104   0.0  
ref|NP_032181.1|  glucose phosphate isomerase 1 [Mus musculu...  1104   0.0  
sp|P06745|G6PI_MOUSE  Glucose-6-phosphate isomerase (GPI) (P...  1104   0.0  
ref|ZP_00724931.1|  COG0166: Glucose-6-phosphate isomerase [...  1103   0.0  
pdb|2CVP|A  Chain A, Crystal Structure Of Mouse Amf >gi|1091...  1103   0.0  
ref|YP_543532.1|  glucose-6-phosphate isomerase [Escherichia...  1103   0.0  
emb|CAC83783.1|  phosphoglucose isomerase [Bufo melanostictus]   1103   0.0  
ref|NP_290659.1|  glucose-6-phosphate isomerase [Escherichia...  1103   0.0  
ref|ZP_00711964.1|  COG0166: Glucose-6-phosphate isomerase [...  1103   0.0  
ref|YP_691477.1|  glucose-6-phosphate isomerase [Shigella fl...  1103   0.0  
ref|NP_838787.1|  glucose-6-phosphate isomerase [Shigella fl...  1103   0.0  
ref|NP_997475.1|  glucose phosphate isomerase [Rattus norveg...  1101   0.0  
prf||1405328A  phosphohexose isomerase                           1101   0.0  
emb|CAA33268.1|  unnamed protein product [Escherichia coli]      1101   0.0  
pdb|1U0E|A  Chain A, Crystal Structure Of Mouse Phosphogluco...  1101   0.0  
dbj|BAE23502.1|  unnamed protein product [Mus musculus]          1101   0.0  
dbj|BAE21866.1|  unnamed protein product [Mus musculus]          1101   0.0  
dbj|BAE35416.1|  unnamed protein product [Mus musculus]          1101   0.0  
dbj|BAE22329.1|  unnamed protein product [Mus musculus]          1101   0.0  
ref|YP_001008017.1|  glucose-6-phosphate isomerase [Yersinia...  1100   0.0  
ref|NP_001006128.1|  glucose phosphate isomerase [Gallus gal...  1099   0.0  
ref|NP_407169.1|  glucose-6-phosphate isomerase [Yersinia pe...  1098   0.0  
dbj|BAF91562.1|  phosphoglucose isomerase [Lepisosteus osseus]   1097   0.0  
ref|ZP_02903962.1|  glucose-6-phosphate isomerase [Escherich...  1097   0.0  
sp|P50309|G6PI_CRIGR  Glucose-6-phosphate isomerase (GPI) (P...  1097   0.0  
gb|AAH83507.1|  Glucose phosphate isomerase a [Danio rerio]      1096   0.0  
ref|NP_994374.1|  glucose-6-phosphate isomerase [Yersinia pe...  1096   0.0  
ref|YP_001436210.1|  hypothetical protein ESA_00069 [Enterob...  1096   0.0  
ref|XP_001490657.1|  PREDICTED: similar to Glucose phosphate...  1096   0.0  
ref|NP_001085765.1|  MGC80718 protein [Xenopus laevis] >gi|4...  1095   0.0  
gb|AAH44450.1|  Glucose phosphate isomerase a [Danio rerio]      1093   0.0  
ref|YP_001480699.1|  Glucose-6-phosphate isomerase [Serratia...  1092   0.0  
emb|CAC83780.1|  phosphoglucose isomerase [Boiga kraepelini]     1091   0.0  
dbj|BAF91559.1|  phosphoglucose isomerase [Polypterus ornati...  1091   0.0  
dbj|BAF91563.1|  phosphoglucose isomerase [Acipenser ruthenus]   1091   0.0  
ref|ZP_02705383.1|  hypothetical protein Salmoentericaenteri...  1090   0.0  
ref|YP_001455405.1|  hypothetical protein CKO_03893 [Citroba...  1090   0.0  
ref|XP_001219077.1|  glucose-6-phosphate isomerase, glycosom...  1090   0.0  
ref|YP_219087.1|  glucose-6-phosphate isomerase [Salmonella ...  1090   0.0  
ref|YP_677101.1|  glucose-6-phosphate isomerase [Cytophaga h...  1090   0.0  
ref|ZP_02685434.1|  glucose-6-phosphate isomerase [Salmonell...  1089   0.0  
ref|ZP_02561519.1|  hypothetical protein Sente_14948 [Salmon...  1089   0.0  
dbj|BAF91556.1|  phosphoglucose isomerase [Amia calva]           1089   0.0  
ref|NP_458519.1|  glucose-6-phosphate isomerase [Salmonella ...  1089   0.0  
ref|YP_001338035.1|  glucose-6-phosphate isomerase [Klebsiel...  1088   0.0  
sp|P13377|G6PI_TRYBB  Glucose-6-phosphate isomerase, glycoso...  1088   0.0  
ref|NP_463086.1|  glucose-6-phosphate isomerase [Salmonella ...  1088   0.0  
dbj|BAF91558.1|  phosphoglucose isomerase-2 [Osteoglossum bi...  1088   0.0  
ref|YP_001572432.1|  hypothetical protein SARI_03461 [Salmon...  1088   0.0  
ref|ZP_02700747.1|  hypothetical protein Saentericaenterica_...  1088   0.0  
ref|ZP_02644649.1|  hypothetical protein Senterenterica_0343...  1088   0.0  
ref|XP_001365167.1|  PREDICTED: similar to phosphoglucose is...  1088   0.0  
ref|ZP_02567671.1|  glucose-6-phosphate isomerase [Salmonell...  1087   0.0  
ref|XP_867955.1|  PREDICTED: similar to Glucose-6-phosphate ...  1087   0.0  
ref|ZP_02680981.1|  hypothetical protein Sentericaenterica_2...  1087   0.0  
ref|NP_001011010.1|  glucose phosphate isomerase [Xenopus tr...  1087   0.0  
ref|ZP_03838871.1|  glucose-6-phosphate isomerase [Citrobact...  1087   0.0  
gb|EEH96038.1|  glucose-6-phosphate isomerase [Citrobacter s...  1086   0.0  
emb|CAC83778.1|  phosphoglucose isomerase [Mugil cephalus]       1086   0.0  
ref|ZP_02833339.1|  hypothetical protein Salentericaenterica...  1086   0.0  
ref|ZP_03827475.1|  glucose-6-phosphate isomerase [Pectobact...  1086   0.0  
emb|CAC83779.1|  phosphoglucose isomerase-2 [Mugil cephalus]     1086   0.0  
ref|ZP_00828371.1|  COG0166: Glucose-6-phosphate isomerase [...  1086   0.0  
ref|YP_153096.1|  glucose-6-phosphate isomerase [Salmonella ...  1086   0.0  
ref|YP_854687.1|  glucose-6-phosphate isomerase [Aeromonas h...  1085   0.0  
ref|YP_052066.1|  glucose-6-phosphate isomerase [Erwinia car...  1085   0.0  
pdb|2O2C|A  Chain A, Crystal Structure Of Phosphoglucose Iso...  1084   0.0  
ref|NP_931552.1|  glucose-6-phosphate isomerase [Photorhabdu...  1084   0.0  
ref|ZP_03900221.1|  glucose-6-phosphate isomerase [Dyadobact...  1084   0.0  
dbj|BAF91561.1|  phosphoglucose isomerase-2 [Anguilla anguilla]  1083   0.0  
ref|NP_658909.1|  glucose phosphate isomerase a [Danio rerio...  1083   0.0  
dbj|BAF91560.1|  phosphoglucose isomerase-1 [Anguilla anguilla]  1082   0.0  
gb|AAI21195.1|  Gpib protein [Danio rerio]                       1082   0.0  
ref|ZP_03830266.1|  glucose-6-phosphate isomerase [Pectobact...  1081   0.0  
ref|ZP_01237153.1|  glucose-6-phosphate isomerase [Vibrio an...  1081   0.0  
ref|ZP_00824080.1|  COG0166: Glucose-6-phosphate isomerase [...  1081   0.0  
ref|ZP_01261693.1|  glucose-6-phosphate isomerase [Vibrio al...  1081   0.0  
ref|ZP_00821566.1|  COG0166: Glucose-6-phosphate isomerase [...  1081   0.0  
emb|CAP09263.1|  glucose phosphate isomerase b [Danio rerio]     1080   0.0  
ref|NP_760318.1|  glucose-6-phosphate isomerase [Vibrio vuln...  1079   0.0  
ref|NP_935768.1|  glucose-6-phosphate isomerase [Vibrio vuln...  1079   0.0  
gb|AAP33062.1|  phosphoglucose isomerase [Vibrio vulnificus]     1079   0.0  
ref|YP_455826.1|  glucose-6-phosphate isomerase [Sodalis glo...  1078   0.0  
dbj|BAF91557.1|  phosphoglucose isomerase-1 [Osteoglossum bi...  1078   0.0  
ref|YP_001143911.1|  glucose-6-phosphate isomerase [Aeromona...  1078   0.0  
ref|ZP_02133202.1|  Transketolase [Desulfatibacillum alkeniv...  1078   0.0  
ref|ZP_01162337.1|  glucose-6-phosphate isomerase [Photobact...  1078   0.0  
ref|NP_799110.1|  glucose-6-phosphate isomerase [Vibrio para...  1078   0.0  
ref|YP_001174971.1|  glucose-6-phosphate isomerase [Enteroba...  1078   0.0  
ref|ZP_01473793.1|  hypothetical protein VEx2w_02003634 [Vib...  1078   0.0  
dbj|BAF91566.1|  phosphoglucose isomerase-2 [Plecoglossus al...  1077   0.0  
gb|ABB76196.1|  phosphoglucose isomerase [Colias eurytheme]      1077   0.0  
gb|ABB76192.1|  phosphoglucose isomerase [Colias eurytheme]      1077   0.0  
ref|ZP_03842012.1|  glucose-6-phosphate isomerase [Proteus m...  1077   0.0  
gb|ABB76189.1|  phosphoglucose isomerase [Colias eurytheme]      1076   0.0  
ref|ZP_01481622.1|  hypothetical protein VchoR_02002478 [Vib...  1076   0.0  
emb|CAC83777.1|  phosphoglucose isomerase [Paramyxine yangi]     1076   0.0  
gb|ABB76190.1|  phosphoglucose isomerase [Colias eurytheme]      1076   0.0  
ref|ZP_01682182.1|  glucose-6-phosphate isomerase [Vibrio ch...  1076   0.0  
gb|ABB76191.1|  phosphoglucose isomerase [Colias eurytheme]      1075   0.0  
ref|ZP_00157128.2|  COG0166: Glucose-6-phosphate isomerase [...  1075   0.0  
ref|NP_658910.1|  glucose phosphate isomerase b [Danio rerio...  1075   0.0  
ref|YP_001909025.1|  Glucose-6-phosphate isomerase (Phosphog...  1075   0.0  
ref|ZP_02961946.1|  hypothetical protein PROSTU_04029 [Provi...  1075   0.0  
ref|NP_001091761.1|  glucose-6-phosphate isomerase [Bombyx m...  1075   0.0  
ref|NP_230028.1|  glucose-6-phosphate isomerase [Vibrio chol...  1075   0.0  
gb|AAX88290.1|  glucose-6-phosphate isomerase [Haemophilus i...  1074   0.0  
gb|ABB00833.1|  phosphoglucose isomerase [Colias eurytheme]      1074   0.0  
gb|ABB76201.1|  phosphoglucose isomerase [Colias meadii]         1074   0.0  
ref|YP_001443299.1|  glucose-6-phosphate isomerase [Vibrio h...  1074   0.0  
ref|ZP_00832585.1|  COG0166: Glucose-6-phosphate isomerase [...  1074   0.0  
gb|ABB76200.1|  phosphoglucose isomerase [Colias meadii]         1074   0.0  
gb|ABB76197.1|  phosphoglucose isomerase [Colias eurytheme]      1073   0.0  
gb|ABB76195.1|  phosphoglucose isomerase [Colias eurytheme]      1073   0.0  
ref|ZP_01795487.1|  glucose-6-phosphate isomerase [Haemophil...  1073   0.0  
dbj|BAF91565.1|  phosphoglucose isomerase-1 [Plecoglossus al...  1073   0.0  
gb|ABB76198.1|  phosphoglucose isomerase [Colias eurytheme]      1072   0.0  
ref|YP_248950.2|  glucose-6-phosphate isomerase [Haemophilus...  1072   0.0  
gb|ABB76199.1|  phosphoglucose isomerase [Colias eurytheme]      1072   0.0  
gb|EDN15559.1|  glucose-6-phosphate isomerase [Vibrio choler...  1072   0.0  
ref|XP_001463984.1|  glucose-6-phosphate isomerase [Leishman...  1071   0.0  
gb|ABB76188.1|  phosphoglucose isomerase [Colias eurytheme]      1071   0.0  
ref|ZP_01793484.1|  glucose-6-phosphate isomerase [Haemophil...  1071   0.0  
ref|XP_001510188.1|  PREDICTED: hypothetical protein [Ornith...  1071   0.0  
ref|ZP_01786798.1|  glucose-6-phosphate isomerase [Haemophil...  1071   0.0  
ref|NP_245353.1|  glucose-6-phosphate isomerase [Pasteurella...  1071   0.0  
emb|CAF05827.1|  glucose-6-phosphate isomerase [Leishmania d...  1070   0.0  
emb|CAF05824.1|  glucose-6-phosphate isomerase [Leishmania d...  1070   0.0  
ref|YP_719149.1|  glucose-6-phosphate isomerase [Haemophilus...  1070   0.0  
ref|YP_001290850.1|  glucose-6-phosphate isomerase [Haemophi...  1070   0.0  
emb|CAJ73656.1|  strongly similar to glucose-6-phosphate iso...  1070   0.0  
ref|XP_970258.1|  PREDICTED: similar to Glucose-6-phosphate ...  1070   0.0  
ref|ZP_02197004.1|  glucose-6-phosphate isomerase [Vibrio ca...  1069   0.0  
ref|XP_001681659.1|  glucose-6-phosphate isomerase [Leishman...  1069   0.0  
ref|ZP_01791410.1|  glucose-6-phosphate isomerase [Haemophil...  1069   0.0  
emb|CAF05839.1|  glucose-6-phosphate isomerase [Leishmania d...  1069   0.0  
emb|CAF05819.1|  glucose-6-phosphate isomerase [Leishmania i...  1069   0.0  
emb|CAF05831.1|  glucose-6-phosphate isomerase [Leishmania i...  1069   0.0  
ref|ZP_01450980.1|  glucose-6-phosphate isomerase [Mariprofu...  1069   0.0  
sp|P42861|G6PI_LEIME  Glucose-6-phosphate isomerase (GPI) (P...  1068   0.0  
ref|ZP_01788697.1|  glucose-6-phosphate isomerase [Haemophil...  1068   0.0  
ref|ZP_02478614.1|  hypothetical protein HPS_11202 [Haemophi...  1068   0.0  
ref|XP_820895.1|  glucose-6-phosphate isomerase, glycosomal,...  1068   0.0  
gb|AAC23219.1|  glucose-6-phosphate isomerase (pgi) [Haemoph...  1067   0.0  
ref|ZP_00155145.1|  COG0166: Glucose-6-phosphate isomerase [...  1067   0.0  
ref|ZP_01869965.1|  glucose-6-phosphate isomerase [Vibrio sh...  1066   0.0  
ref|YP_001291516.1|  glucose-6-phosphate isomerase [Haemophi...  1065   0.0  
ref|NP_439722.2|  glucose-6-phosphate isomerase [Haemophilus...  1065   0.0  
ref|YP_001784733.1|  Glucose-6-phosphate isomerase [Haemophi...  1065   0.0  
ref|YP_203687.1|  glucosephosphate isomerase [Vibrio fischer...  1064   0.0  
ref|YP_001053832.1|  glucose-6-phosphate isomerase [Actinoba...  1063   0.0  
ref|XP_001599986.1|  PREDICTED: similar to phosphoglucose is...  1063   0.0  
ref|ZP_00135214.1|  COG0166: Glucose-6-phosphate isomerase [...  1062   0.0  
gb|EDN74431.1|  glucose-6-phosphate isomerase [Mannheimia ha...  1062   0.0  
ref|ZP_01816475.1|  glucose-6-phosphate isomerase [Vibrional...  1062   0.0  
ref|YP_131428.1|  glucose-6-phosphate isomerase [Photobacter...  1062   0.0  
ref|YP_001652156.1|  glucose-6-phosphate isomerase [Actinoba...  1061   0.0  
ref|XP_821969.1|  glucose-6-phosphate isomerase, glycosomal,...  1060   0.0  
ref|ZP_01222432.1|  glucose-6-phosphate isomerase [Photobact...  1060   0.0  
ref|YP_001344719.1|  Glucose-6-phosphate isomerase [Actinoba...  1060   0.0  
ref|ZP_00991932.1|  glucose-6-phosphate isomerase [Vibrio sp...  1059   0.0  
ref|ZP_01066513.1|  glucose-6-phosphate isomerase [Vibrio sp...  1059   0.0  
ref|YP_088373.1|  glucose-6-phosphate isomerase [Mannheimia ...  1059   0.0  
sp|Q1H1P4|G6PI_METFK  Glucose-6-phosphate isomerase (GPI) (P...  1056   0.0  
ref|ZP_01883305.1|  glucose-6-phosphate isomerase [Pedobacte...  1053   0.0  
ref|YP_847696.1|  phosphoglucose isomerase (PGI) [Syntrophob...  1052   0.0  
ref|ZP_01215739.1|  glucose-6-phosphate isomerase [Psychromo...  1051   0.0  
ref|XP_001749895.1|  predicted protein [Monosiga brevicollis...  1049   0.0  
sp|P52030|G6PI_DROSI  Glucose-6-phosphate isomerase (GPI) (P...  1048   0.0  
sp|P52031|G6PI_DROYA  Glucose-6-phosphate isomerase (GPI) (P...  1048   0.0  
gb|AAA28809.1|  glucose-6-phosphate isomerase                    1047   0.0  
ref|XP_001361508.1|  GA20931-PA [Drosophila pseudoobscura] >...  1047   0.0  
ref|ZP_01900582.1|  glucose-6-phosphate isomerase [Moritella...  1046   0.0  
gb|AAA28797.1|  glucosephosphate isomerase >gi|443615|gb|AAA...  1046   0.0  
ref|ZP_00511177.1|  Glucose-6-phosphate isomerase [Chlorobiu...  1045   0.0  
gb|AAA28789.1|  glucosephosphate isomerase >gi|443601|gb|AAA...  1045   0.0  
gb|AAA28813.1|  glucose-6-phosphate isomerase                    1045   0.0  
ref|NP_523663.1|  Phosphoglucose isomerase CG8251-PA, isofor...  1045   0.0  
gb|AAA63672.1|  glucosephosphate isomerase                       1044   0.0  
ref|YP_604769.1|  Glucose-6-phosphate isomerase [Deinococcus...  1044   0.0  
ref|XP_001629102.1|  predicted protein [Nematostella vectens...  1044   0.0  
gb|AAA28804.1|  glucose-6-phosphate isomerase                    1041   0.0  
ref|YP_941789.1|  Glucose-6-phosphate isomerase [Psychromona...  1041   0.0  
ref|ZP_01386716.1|  Glucose-6-phosphate isomerase [Chlorobiu...  1038   0.0  
ref|ZP_00531578.1|  Glucose-6-phosphate isomerase [Chlorobiu...  1036   0.0  
ref|XP_001663180.1|  glucose-6-phosphate isomerase [Aedes ae...  1036   0.0  
ref|YP_113710.1|  glucose-6-phosphate isomerase [Methylococc...  1036   0.0  
ref|NP_872994.1|  glucose-6-phosphate isomerase [Haemophilus...  1034   0.0  
ref|ZP_01720871.1|  glucose-6-phosphate isomerase [Algoripha...  1033   0.0  
ref|NP_001021838.1|  Glucose-6-Phosphate Isomerase family me...  1032   0.0  
ref|XP_001848359.1|  glucose-6-phosphate isomerase [Culex pi...  1032   0.0  
ref|YP_865849.1|  Glucose-6-phosphate isomerase [Magnetococc...  1032   0.0  
ref|YP_545434.1|  Glucose-6-phosphate isomerase [Methylobaci...  1032   0.0  
ref|XP_638957.1|  glucose-6-phosphate isomerase [Dictyosteli...  1031   0.0  
emb|CAP27938.1|  C. briggsae CBR-GPI-1 protein [Caenorhabdit...  1031   0.0  
ref|XP_320366.3|  AGAP012167-PA [Anopheles gambiae str. PEST...  1030   0.0  
ref|NP_295465.1|  glucose-6-phosphate isomerase [Deinococcus...  1030   0.0  
ref|NP_001021837.1|  Glucose-6-Phosphate Isomerase family me...  1029   0.0  
sp|Q3B3Q8|G6PI_PELLD  Glucose-6-phosphate isomerase (GPI) (P...  1027   0.0  
ref|YP_375066.1|  Glucose-6-phosphate isomerase [Pelodictyon...  1027   0.0  
ref|YP_342945.1|  Glucose-6-phosphate isomerase [Nitrosococc...  1027   0.0  
ref|YP_378928.1|  glucose-6-phosphate isomerase [Chlorobium ...  1027   0.0  
ref|ZP_00592941.1|  Glucose-6-phosphate isomerase [Prostheco...  1027   0.0  
gb|ABH11436.1|  cytosolic glucose-6-phosphate isomerase [Pav...  1026   0.0  
ref|XP_001563099.1|  glucose-6-phosphate isomerase [Leishman...  1025   0.0  
gb|ABU25166.1|  glucose-6-phosphate isomerase [Leishmania gu...  1024   0.0  
ref|YP_002786433.1|  putative glucose-6-phosphate isomerase ...  1024   0.0  
gb|ABU25168.1|  glucose-6-phosphate isomerase [Leishmania la...  1024   0.0  
gb|ABU25165.1|  glucose-6-phosphate isomerase [Leishmania br...  1024   0.0  
ref|YP_001130308.1|  Glucose-6-phosphate isomerase [Prosthec...  1023   0.0  
ref|XP_623552.1|  PREDICTED: similar to Glucose-6-phosphate ...  1022   0.0  
ref|XP_001900986.1|  glucose phosphate isomerase a [Brugia m...  1019   0.0  
gb|ABI49145.1|  glucose-6-phosphate isomerase [Trimastix pyr...  1019   0.0  
ref|NP_661881.1|  glucose-6-phosphate isomerase [Chlorobium ...  1018   0.0  
gb|ABH11435.2|  cytosolic glucose-6-phosphate isomerase [Emi...  1018   0.0  
ref|ZP_00588749.1|  Glucose-6-phosphate isomerase [Pelodicty...  1018   0.0  
ref|YP_423777.1|  Glucose-6-phosphate isomerase [Magnetospir...  1014   0.0  
gb|AAG15513.1|U65476_1  phosphoglucose isomerase; glucose-6-...  1014   0.0  
ref|YP_911560.1|  Glucose-6-phosphate isomerase [Chlorobium ...  1011   0.0  
gb|ABH11445.1|  cytosolic glucose-6-phosphate isomerase [Pha...  1011   0.0  
ref|ZP_00055322.1|  COG0166: Glucose-6-phosphate isomerase [...  1011   0.0  
dbj|BAE53447.1|  Glucosephosphate isomerase [Entamoeba histo...  1009   0.0  
sp|Q1IYT4|G6PI_DEIGD  Glucose-6-phosphate isomerase (GPI) (P...  1009   0.0  
dbj|BAE53448.1|  Glucosephosphate isomerase [Entamoeba histo...  1009   0.0  
ref|XP_650595.1|  glucose-6-phosphate isomerase, putative [E...  1009   0.0  
pdb|1Q50|A  Chain A, Phosphoglucose Isomerase From Leishmani...  1008   0.0  
ref|YP_315821.1|  glucose-6-phosphate isomerase [Thiobacillu...  1006   0.0  
ref|NP_924638.1|  glucose-6-phosphate isomerase [Gloeobacter...  1006   0.0  
sp|Q3SH73|G6PI2_THIDA  Glucose-6-phosphate isomerase 2 (GPI ...  1005   0.0  
ref|XP_001741106.1|  glucose-6-phosphate isomerase, putative...  1004   0.0  
dbj|BAC36335.1|  unnamed protein product [Mus musculus]          1004   0.0  
ref|YP_001430850.1|  Glucose-6-phosphate isomerase [Roseifle...  1001   0.0  
ref|ZP_01088891.1|  glucose-6-phosphate isomerase [Blastopir...   999   0.0  
dbj|BAF57007.1|  glucose-6-phosphate isomerase 1 [Entamoeba ...   997   0.0  
dbj|BAF57008.1|  glucose-6-phosphate isomerase 2 [Entamoeba ...   994   0.0  
emb|CAA82246.1|  glucosephosphate isomerase [Sus scrofa]          994   0.0  
ref|NP_899819.1|  glucose-6-phosphate isomerase [Chromobacte...   994   0.0  
ref|YP_588491.1|  glucose-6-phosphate isomerase [Baumannia c...   993   0.0  
gb|ABS81352.1|  phosphoglucose isomerase [Echinococcus multi...   992   0.0  
gb|AAX73170.1|  putative glucose phosphate isomerase [Echino...   991   0.0  
ref|ZP_02733949.1|  glucose-6-phosphate isomerase [Gemmata o...   989   0.0  
ref|ZP_03850867.1|  glucose-6-phosphate isomerase [Chryseoba...   988   0.0  
ref|ZP_01854838.1|  glucose-6-phosphate isomerase / glucose-...   988   0.0  
ref|XP_001839617.1|  hypothetical protein CC1G_10610 [Coprin...   987   0.0  
ref|YP_001278641.1|  glucose-6-phosphate isomerase [Roseifle...   985   0.0  
gb|AAT91251.1|  Glc-6-P isomerase [Paxillus involutus]            984   0.0  
ref|YP_428031.1|  Glucose-6-phosphate isomerase [Rhodospiril...   984   0.0  
ref|NP_596635.1|  glucose-6-phosphate isomerase (predicted) ...   984   0.0  
ref|YP_002754143.1|  glucose-6-phosphate isomerase [Acidobac...   983   0.0  
emb|CAM76547.1|  Glucose-6-phosphate isomerase [Magnetospiri...   981   0.0  
ref|XP_777368.1|  hypothetical protein CNBB1690 [Cryptococcu...   979   0.0  
ref|YP_460809.1|  glucose-6-phosphate isomerase / glucose-6 ...   979   0.0  
ref|XP_569228.1|  glucose-6-phosphate isomerase [Cryptococcu...   979   0.0  
ref|NP_274402.1|  glucose-6-phosphate isomerase [Neisseria m...   979   0.0  
ref|XP_001240681.1|  glucose-6-phosphate isomerase [Coccidio...   978   0.0  
gb|EDU44288.1|  glucose-6-phosphate isomerase [Pyrenophora t...   978   0.0  
ref|XP_001882557.1|  glucose-6-phosphate isomerase [Laccaria...   978   0.0  
ref|XP_001537093.1|  glucose-6-phosphate isomerase [Ajellomy...   977   0.0  
ref|YP_001599432.1|  glucose-6-phosphate isomerase [Neisseri...   977   0.0  
ref|YP_357776.2|  glucose phosphate isomerase [Pelobacter ca...   976   0.0  
ref|YP_001827090.1|  putative glucose-6-phosphate isomerase ...   975   0.0  
ref|YP_975337.1|  glucose-6-phosphate isomerase [Neisseria m...   975   0.0  
ref|YP_207851.1|  glucose-6-phosphate isomerase [Neisseria g...   975   0.0  
ref|XP_001803813.1|  hypothetical protein SNOG_13608 [Phaeos...   975   0.0  
ref|ZP_01797300.1|  glucose-6-phosphate isomerase [Haemophil...   974   0.0  
ref|NP_284321.1|  glucose-6-phosphate isomerase [Neisseria m...   972   0.0  
dbj|BAG13901.1|  glucose-6-phosphate isomerase [uncultured T...   972   0.0  
ref|YP_278131.1|  glucose-6-phosphate isomerase [Candidatus ...   971   0.0  
dbj|BAA13929.1|  unnamed protein product [Schizosaccharomyce...   969   0.0  
ref|NP_878897.1|  glucose-6-phosphate isomerase [Candidatus ...   968   0.0  
ref|YP_001673349.1|  Glucose-6-phosphate isomerase [Shewanel...   968   0.0  
ref|NP_827478.1|  glucose-6-phosphate isomerase [Streptomyce...   967   0.0  
sp|Q711G1|G6PI_AGABI  Glucose-6-phosphate isomerase (GPI) (P...   966   0.0  
ref|ZP_01062120.1|  glucose-6-phosphate isomerase [Flavobact...   966   0.0  
ref|NP_009755.1|  Glycolytic enzyme phosphoglucose isomerase...   965   0.0  
ref|XP_460936.1|  hypothetical protein DEHA0F14289g [Debaryo...   965   0.0  
ref|XP_455013.1|  G6PI_KLULA [Kluyveromyces lactis] >gi|5278...   965   0.0  
ref|YP_411169.1|  glucose-6-phosphate isomerase [Nitrosospir...   962   0.0  
ref|YP_001500935.1|  Glucose-6-phosphate isomerase [Shewanel...   962   0.0  
ref|XP_001732736.1|  hypothetical protein MGL_0511 [Malassez...   961   0.0  
pir||T27469  hypothetical protein Y87G2A.q - Caenorhabditis ...   961   0.0  
Sequences not found previously or not previously below threshold:

gb|EDM07646.1|  glucose phosphate isomerase [Rattus norvegicus]   990   0.0  
>ref|XP_867960.1| PREDICTED: similar to Glucose-6-phosphate isomerase (GPI)
           (Phosphoglucose isomerase) (PGI) (Phosphohexose
           isomerase) (PHI) (Neuroleukin) (NLK) (Sperm antigen-36)
           (SA-36) isoform 3 [Canis familiaris]
          Length = 563

 Score = 1133 bits (2932), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/560 (57%), Positives = 416/560 (74%), Gaps = 7/560 (1%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQK + + G D  +++ FE D ER  R+S+ ++    +   + +DYSK+ +
Sbjct: 4   LTQSPQFQKLQKWHREQGSDLNLRRLFEGDKERFNRFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            D +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TDTVMQMLVDLAKSRGVEAARERMFSGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNRVLEKMKSFCQRVRSGEWKGYSGKPITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHI++ L +++ E++LFI+ASKTFTTQETITNA +A+   L   +   +  
Sbjct: 181 VWFVSNIDGTHISKTLAALNPESSLFIIASKTFTTQETITNAETAKEWFLLSAKDVNMSV 240

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 241 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 300

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 301 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETQAMLPYDQYLHRFAAYFQQG 360

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 361 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 420

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 421 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 479

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 480 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 539

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HDSSTNGLIN   +   
Sbjct: 540 VTSHDSSTNGLINFIKQERE 559
>ref|XP_853858.1| PREDICTED: similar to Glucose-6-phosphate isomerase (GPI)
           (Phosphoglucose isomerase) (PGI) (Phosphohexose
           isomerase) (PHI) (Neuroleukin) (NLK) (Sperm antigen-36)
           (SA-36) isoform 1 [Canis familiaris]
          Length = 558

 Score = 1131 bits (2928), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/560 (57%), Positives = 415/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQK + + G D  +++ FE D ER  R+S+ ++    +   + +DYSK+ +
Sbjct: 4   LTQSPQFQKLQKWHREQGSDLNLRRLFEGDKERFNRFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            D +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TDTVMQMLVDLAKSRGVEAARERMFSGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNRVLEKMKSFCQRVRSGEWKGYSGKPITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHI++ L +++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 181 VWFVSNIDGTHISKTLAALNPESSLFIIASKTFTTQETITNAETAKEWFL-----LSAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETQAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HDSSTNGLIN   +   
Sbjct: 535 VTSHDSSTNGLINFIKQERE 554
>ref|NP_999495.1| glucose phosphate isomerase [Sus scrofa]
 sp|P08059|G6PI_PIG Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 emb|CAA30295.1| unnamed protein product [Sus scrofa]
          Length = 558

 Score = 1130 bits (2923), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/560 (57%), Positives = 416/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ  Y ++  D  +++ FE D +R   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTQNPQFKKLQTWYHEHRSDLNLRRLFEGDKDRFNHFSLNLN---TNHGRILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            + +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEAVMQMLVDLAKSRGVEAARERMFNGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK+I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNRVLEKMKSFCKRVRSGEWKGYSGKSITDVINIGIGGSDLGPLMVTEALKPYSAEGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L +++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWFVSNIDGTHIAKTLATLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QSAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYINFFG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINFFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E    LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDFEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HDSSTNGLIN   +   
Sbjct: 535 VTSHDSSTNGLINFIKQERE 554
>pdb|1GZD|A Chain A, Crystal Structure Of Pig Phosphoglucose Isomerase
 pdb|1GZV|A Chain A, The Crystal Structure Of Phosphoglucose Isomerase From Pig
           Muscle Complexed With 5-Phosphoarabinonate
          Length = 557

 Score = 1130 bits (2923), Expect = 0.0,   Method: Composition-based stats.
 Identities = 321/560 (57%), Positives = 416/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ  Y ++  D  +++ FE D +R   +S+ ++    +   + LDYSK+ +
Sbjct: 3   LTQNPQFKKLQTWYHEHRSDLNLRRLFEGDKDRFNHFSLNLN---TNHGRILLDYSKNLV 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            + +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 60  TEAVMQMLVDLAKSRGVEAARERMFNGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK+I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 120 EVNRVLEKMKSFCKRVRSGEWKGYSGKSITDVINIGIGGSDLGPLMVTEALKPYSAEGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L +++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 180 VWFVSNIDGTHIAKTLATLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QSAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYINFFG  THA+LPYDQYL R  AY QQ 
Sbjct: 295 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINFFGCETHAMLPYDQYLHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 355 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 414

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E    LLPHK F G RP+
Sbjct: 415 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDFEKLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 474 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 533

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HDSSTNGLIN   +   
Sbjct: 534 VTSHDSSTNGLINFIKQERE 553
>ref|XP_867967.1| PREDICTED: similar to Glucose-6-phosphate isomerase (GPI)
           (Phosphoglucose isomerase) (PGI) (Phosphohexose
           isomerase) (PHI) (Neuroleukin) (NLK) (Sperm antigen-36)
           (SA-36) isoform 4 [Canis familiaris]
          Length = 561

 Score = 1125 bits (2912), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/560 (57%), Positives = 414/560 (73%), Gaps = 9/560 (1%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQK + + G D  +++ FE D ER  R+S+ ++    +   + +DYSK+ +
Sbjct: 4   LTQSPQFQKLQKWHREQGSDLNLRRLFEGDKERFNRFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            D +   L+ LA+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TDTVMQMLVDLAKSRGVEAARERMFSGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNRVLEKMKSFCQRVRSGEWKGYSGKPITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHI++ L +++ E++LFI+ASKTFTTQETITNA +A+   L   +      
Sbjct: 181 VWFVSNIDGTHISKTLAALNPESSLFIIASKTFTTQETITNAETAKEWFLLSAKDVSAG- 239

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
              +AKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 240 -VGIAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 298

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 299 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETQAMLPYDQYLHRFAAYFQQG 358

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 359 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 418

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 419 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 477

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 478 NSIVFTKLTPFILGALIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSP 537

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HDSSTNGLIN   +   
Sbjct: 538 VTSHDSSTNGLINFIKQERE 557
>ref|NP_001035561.1| glucose phosphate isomerase [Bos taurus]
 sp|Q3ZBD7|G6PI_BOVIN Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAI03417.1| Glucose phosphate isomerase [Bos taurus]
          Length = 557

 Score = 1124 bits (2909), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/560 (57%), Positives = 418/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L+  YEQ+G D  +++ FE D +R  R+S+ ++    +   + +DYSK+ +
Sbjct: 4   LTQNPQFKKLKTWYEQHGSDLNLRRLFEGDRDRFNRFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            + +   L+ +A+ RG+    + +F GE++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TETVMQMLVDVAKSRGVEAARERMFTGEKINFTEDRAVLHVALRNRSNAPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VL++M+SF ++VR+GEWKG++GKAI  V+NIGIGGSDLGP+M TE+LKP+S     
Sbjct: 121 EVNRVLEKMKSFCQRVRSGEWKGYSGKAITDVINIGIGGSDLGPLMVTESLKPYSSEGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L +++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 181 VWFVSNIDGTHIAKTLATLNPESSLFIIASKTFTTQETITNAETAKEWFL-----LSAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V+  TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +QSQ+ 
Sbjct: 356 DMESNGKYITKSGTRVNYQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQSQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG RS E    LLPHK F G RP+
Sbjct: 416 IRNGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-RSPEDFEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HDSSTNGLIN   +   
Sbjct: 535 VTSHDSSTNGLINFIKQERE 554
>sp|Q4R591|G6PI_MACFA Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 dbj|BAE01734.1| unnamed protein product [Macaca fascicularis]
          Length = 558

 Score = 1120 bits (2899), Expect = 0.0,   Method: Composition-based stats.
 Identities = 319/560 (56%), Positives = 417/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++G    +++ F+AD +R   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHGSELNLRRLFDADKDRFNHFSLTLN---TNHGHILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSEGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLTQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMRGKSTDEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HD+STNGLIN   +   
Sbjct: 535 VTSHDASTNGLINFIKQQRE 554
>pdb|1IAT|A Chain A, Crystal Structure Of Human Phosphoglucose
           IsomeraseNEUROLEUKINAUTOCRINE MOTILITY FACTORMATURATION
           Factor
          Length = 557

 Score = 1120 bits (2899), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/560 (56%), Positives = 416/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 3   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 60  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 120 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 180 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 295 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 355 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 414

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 415 IRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 474 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 533

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HD+STNGLIN   +   
Sbjct: 534 VTSHDASTNGLINFIKQQRE 553
>ref|NP_000166.2| glucose phosphate isomerase [Homo sapiens]
 sp|P06744|G6PI_HUMAN Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI) (Neuroleukin)
           (NLK) (Sperm antigen 36) (SA-36)
 pdb|1IRI|A Chain A, Crystal Structure Of Human Autocrine Motility Factor
           Complexed With An Inhibitor
 pdb|1IRI|B Chain B, Crystal Structure Of Human Autocrine Motility Factor
           Complexed With An Inhibitor
 pdb|1IRI|C Chain C, Crystal Structure Of Human Autocrine Motility Factor
           Complexed With An Inhibitor
 pdb|1IRI|D Chain D, Crystal Structure Of Human Autocrine Motility Factor
           Complexed With An Inhibitor
 pdb|1JIQ|A Chain A, Crystal Structure Of Human Autocrine Motility Factor
 pdb|1JIQ|B Chain B, Crystal Structure Of Human Autocrine Motility Factor
 pdb|1JIQ|C Chain C, Crystal Structure Of Human Autocrine Motility Factor
 pdb|1JIQ|D Chain D, Crystal Structure Of Human Autocrine Motility Factor
 pdb|1NUH|A Chain A, The Crystal Structure Of Human Phosphoglucose Isomerase
           Complexed With 5-Phosphoarabinonate
 gb|AAH04982.1| Glucose phosphate isomerase [Homo sapiens]
 gb|AAP72966.1| glucose phosphate isomerase [Homo sapiens]
 gb|ABM83850.1| glucose phosphate isomerase [synthetic construct]
 gb|ABM87172.1| glucose phosphate isomerase [synthetic construct]
          Length = 558

 Score = 1120 bits (2899), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/560 (56%), Positives = 416/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HD+STNGLIN   +   
Sbjct: 535 VTSHDASTNGLINFIKQQRE 554
>gb|AAP36518.1| Homo sapiens glucose phosphate isomerase [synthetic construct]
 gb|AAX28981.1| glucose phosphate isomerase [synthetic construct]
 gb|AAX28982.1| glucose phosphate isomerase [synthetic construct]
          Length = 559

 Score = 1120 bits (2899), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/560 (56%), Positives = 416/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HD+STNGLIN   +   
Sbjct: 535 VTSHDASTNGLINFIKQQRE 554
>pdb|1JLH|A Chain A, Human Glucose-6-Phosphate Isomerase
 pdb|1JLH|B Chain B, Human Glucose-6-Phosphate Isomerase
 pdb|1JLH|C Chain C, Human Glucose-6-Phosphate Isomerase
 pdb|1JLH|D Chain D, Human Glucose-6-Phosphate Isomerase
          Length = 558

 Score = 1118 bits (2893), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/560 (56%), Positives = 416/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTEMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HD+STNGLIN   +   
Sbjct: 535 VTSHDASTNGLINFIKQQRE 554
>gb|AAF22645.1|AF187554_1 sperm antigen-36 [Homo sapiens]
          Length = 558

 Score = 1117 bits (2890), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/560 (56%), Positives = 416/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEA+M GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILVANFLAQTEAVMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HD+STNGLIN   +   
Sbjct: 535 VTSHDASTNGLINFIKQQRE 554
>gb|AAA36368.1| neuroleukin
 gb|AAB36062.1| glucose phosphate isomerase, GPI {EC 5.3.1.9} [Homo sapiens=human,
           leukocyte, Peptide, 558 aa]
          Length = 558

 Score = 1116 bits (2887), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/560 (56%), Positives = 415/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++     +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  V+NIGI GSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIVGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HD+STNGLIN   +   
Sbjct: 535 VTSHDASTNGLINFIKQQRE 554
>pdb|1N8T|A Chain A, The Crystal Structure Of Phosphoglucose Isomerase From
           Rabbit Muscle
 pdb|1N8T|B Chain B, The Crystal Structure Of Phosphoglucose Isomerase From
           Rabbit Muscle
          Length = 557

 Score = 1115 bits (2886), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/560 (57%), Positives = 415/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G    ++  F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 3   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 60  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 120 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 180 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAETAKDWFL-----LSAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 295 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 355 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 414

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 415 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 474 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 533

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HDSSTNGLIN   +   
Sbjct: 534 VTSHDSSTNGLINFIKQQRE 553
>ref|NP_001075538.1| phosphoglucose isomerase [Oryctolagus cuniculus]
 sp|Q9N1E2|G6PI_RABIT Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAF13713.2|AF199601_1 phosphoglucose isomerase [Oryctolagus cuniculus]
          Length = 558

 Score = 1115 bits (2886), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/560 (57%), Positives = 415/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G    ++  F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 181 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAETAKDWFL-----LSAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HDSSTNGLIN   +   
Sbjct: 535 VTSHDSSTNGLINFIKQQRE 554
>pdb|1DQR|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase, A
           Glycolytic Enzyme That Moonlights As Neuroleukin,
           Autocrine Motility Factor, And Differentiation Mediator
 pdb|1DQR|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase, A
           Glycolytic Enzyme That Moonlights As Neuroleukin,
           Autocrine Motility Factor, And Differentiation Mediator
 pdb|1KOJ|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With 5-Phospho-D-Arabinonohydroxamic Acid
 pdb|1KOJ|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With 5-Phospho-D-Arabinonohydroxamic Acid
          Length = 557

 Score = 1115 bits (2884), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/560 (57%), Positives = 415/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G    ++  F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 3   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 59

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 60  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 119

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 120 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 179

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 180 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAKTAKDWFL-----LSAKD 234

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 235 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 294

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 295 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 354

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 355 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 414

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 415 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 473

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 474 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 533

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HDSSTNGLIN   +   
Sbjct: 534 VTSHDSSTNGLINFIKQQRE 553
>pdb|1G98|A Chain A, Crystal Structure Analysis Of Rabbit Phosphoglucose
           Isomerase Complexed With 5-Phosphoarabinonate, A
           Transition State Analogue
 pdb|1G98|B Chain B, Crystal Structure Analysis Of Rabbit Phosphoglucose
           Isomerase Complexed With 5-Phosphoarabinonate, A
           Transition State Analogue
 pdb|1HOX|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Fructose-6-Phosphate
 pdb|1HOX|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Fructose-6-Phosphate
 pdb|1HM5|A Chain A, Crystal Structure Analysis Of The Rabbit D-Glucose 6-
           Phosphate Isomerase (No Ligand Bound)
 pdb|1HM5|B Chain B, Crystal Structure Analysis Of The Rabbit D-Glucose 6-
           Phosphate Isomerase (No Ligand Bound)
 pdb|1XTB|A Chain A, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Sorbitol-6-Phosphate
 pdb|1XTB|B Chain B, Crystal Structure Of Rabbit Phosphoglucose Isomerase
           Complexed With Sorbitol-6-Phosphate
 gb|AAF35988.1|AF222069_1 phosphoglucose isomerase [Oryctolagus cuniculus]
          Length = 558

 Score = 1115 bits (2884), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/560 (57%), Positives = 415/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ + ++G    ++  F+ D ER   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTRNPQFQKLQQWHREHGSELNLRHLFDTDKERFNHFSLTLN---TNHGHILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +E+   LL LA+ RG+    +S+F GE++N+TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEEVMHMLLDLAKSRGVEAARESMFNGEKINSTEDRAVLHVALRNRSNTPIVVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M++F ++VR+G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKAFCQRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L  ++ E++LFI+ASKTFTTQETITNA +A+   L         +
Sbjct: 181 VWFVSNIDGTHIAKTLACLNPESSLFIIASKTFTTQETITNAKTAKDWFL-----LSAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSTVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLA++G+WYIN FG  T A+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLAMLGIWYINCFGCETQAVLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLMKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGVVWDINSFDQWGVELGKQLAKKIEPELDGSSP 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HDSSTNGLIN   +   
Sbjct: 535 VTSHDSSTNGLINFIKQQRE 554
>sp|Q5R4E3|G6PI_PONPY Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 emb|CAH93373.1| hypothetical protein [Pongo abelii]
          Length = 558

 Score = 1111 bits (2875), Expect = 0.0,   Method: Composition-based stats.
 Identities = 313/560 (55%), Positives = 416/560 (74%), Gaps = 12/560 (2%)

Query: 50  LTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +LQ+ Y ++G    +++ F+A+ +R   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRDPQFQKLQQWYREHGSELNLRRLFDANKDRFNHFSLTLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
            +++   L+ LA+ RG+    + +F GE++N TE R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  TEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGK I  ++NIGIGGSDLGP+M TEALKP+S     
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKTITDIINIGIGGSDLGPLMVTEALKPYSSGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + +VSN+DGTHIA+ L  ++ E+++ I+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWYVSNIDGTHIAKTLAQLNPESSVSIIASKTFTTQETITNAETAKEWFL-----QTAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +
Sbjct: 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  THA+LPYDQYL R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHK+ ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKVLLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDLERLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA++AMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L    +
Sbjct: 475 NSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQ 534

Query: 587 VNNHDSSTNGLINMFNELSH 606
           V +HD+STNGLIN   +   
Sbjct: 535 VTSHDASTNGLINFIKQQRE 554
>ref|YP_001746414.1| glucose-6-phosphate isomerase [Escherichia coli SMS-3-5]
 gb|ACB18320.1| glucose-6-phosphate isomerase [Escherichia coli SMS-3-5]
          Length = 549

 Score = 1104 bits (2857), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/561 (56%), Positives = 407/561 (72%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   T  A+W  LQK +++  D  I   F  D +R  ++SV        ++ + +DYS
Sbjct: 1   MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSVTF------DDQMLVDYS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGK
Sbjct: 55  KNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +
Sbjct: 174 NHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----K 228

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++
Sbjct: 229 AAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFD 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NFVELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY
Sbjct: 289 NFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G R
Sbjct: 409 THNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+  
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             +++HDSSTNGLIN +    
Sbjct: 528 KEISSHDSSTNGLINRYKAWR 548
>ref|NP_032181.1| glucose phosphate isomerase 1 [Mus musculus]
 gb|AAA39825.1| neuroleukin
 dbj|BAE41301.1| unnamed protein product [Mus musculus]
          Length = 558

 Score = 1104 bits (2857), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/559 (56%), Positives = 414/559 (74%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQY-GDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L + +     +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTEDRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+        +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEA-----AKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLI+   +  
Sbjct: 535 VTSHDSSTNGLISFIKQQR 553
>sp|P06745|G6PI_MOUSE Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI) (Neuroleukin)
           (NLK)
 gb|AAH86640.1| Glucose phosphate isomerase 1 [Mus musculus]
 gb|AAH88995.1| Glucose phosphate isomerase 1 [Mus musculus]
 dbj|BAE27695.1| unnamed protein product [Mus musculus]
 dbj|BAE29481.1| unnamed protein product [Mus musculus]
 emb|CAM21756.1| glucose phosphate isomerase 1 [Mus musculus]
          Length = 558

 Score = 1104 bits (2856), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/559 (56%), Positives = 414/559 (74%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQY-GDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L + +     +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TENR VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+        +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEA-----AKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLI+   +  
Sbjct: 535 VTSHDSSTNGLISFIKQQR 553
>ref|ZP_00724931.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli F11]
 ref|YP_672094.1| glucose-6-phosphate isomerase [Escherichia coli 536]
 ref|YP_859617.1| glucose-6-phosphate isomerase [Escherichia coli APEC O1]
 ref|NP_756843.2| glucose-6-phosphate isomerase [Escherichia coli CFT073]
 sp|Q8FB44|G6PI_ECOL6 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|A1AIK3|G6PI_ECOK1 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q0TA36|G6PI_ECOL5 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q1R3R3|G6PI_ECOUT Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|ABG72193.1| glucose-6-phosphate isomerase [Escherichia coli 536]
 gb|ABJ03493.1| glucose-6-phosphate isomerase [Escherichia coli APEC O1]
          Length = 549

 Score = 1103 bits (2855), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/561 (56%), Positives = 407/561 (72%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   T  A+W  LQK +++  D  I   F  D +R  ++S         ++ + +DYS
Sbjct: 1   MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATF------DDQMLVDYS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGK
Sbjct: 55  KNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +
Sbjct: 174 NHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----K 228

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++
Sbjct: 229 AAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFD 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NFVELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY
Sbjct: 289 NFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+GK V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGKVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G R
Sbjct: 409 THNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+  
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             +++HDSSTNGLIN +    
Sbjct: 528 KEISSHDSSTNGLINRYKAWR 548
>pdb|2CVP|A Chain A, Crystal Structure Of Mouse Amf
 pdb|2CVP|B Chain B, Crystal Structure Of Mouse Amf
 pdb|2CXN|A Chain A, Crystal Structure Of Mouse Amf  PHOSPHATE COMPLEX
 pdb|2CXN|B Chain B, Crystal Structure Of Mouse Amf  PHOSPHATE COMPLEX
 pdb|2CXO|A Chain A, Crystal Structure Of Mouse Amf  E4P COMPLEX
 pdb|2CXO|B Chain B, Crystal Structure Of Mouse Amf  E4P COMPLEX
 pdb|2CXP|A Chain A, Crystal Structure Of Mouse Amf  A5P COMPLEX
 pdb|2CXP|B Chain B, Crystal Structure Of Mouse Amf  A5P COMPLEX
 pdb|2CXQ|A Chain A, Crystal Structure Of Mouse Amf  S6P COMPLEX
 pdb|2CXQ|B Chain B, Crystal Structure Of Mouse Amf  S6P COMPLEX
 pdb|2CXR|A Chain A, Crystal Structure Of Mouse Amf  6PG COMPLEX
 pdb|2CXR|B Chain B, Crystal Structure Of Mouse Amf  6PG COMPLEX
 pdb|2CXS|A Chain A, Crystal Structure Of Mouse Amf  F6P COMPLEX
 pdb|2CXS|B Chain B, Crystal Structure Of Mouse Amf  F6P COMPLEX
 pdb|2CXT|A Chain A, Crystal Structure Of Mouse Amf  F6P COMPLEX
 pdb|2CXT|B Chain B, Crystal Structure Of Mouse Amf  F6P COMPLEX
 pdb|2CXU|A Chain A, Crystal Structure Of Mouse Amf  M6P COMPLEX
 pdb|2CXU|B Chain B, Crystal Structure Of Mouse Amf  M6P COMPLEX
          Length = 557

 Score = 1103 bits (2855), Expect = 0.0,   Method: Composition-based stats.
 Identities = 314/559 (56%), Positives = 414/559 (74%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQY-GDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L + +     +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           + E+   L+ LA+ RG+     ++F G ++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  SKEVMQMLVELAKSRGVEAARDNMFSGSKINYTEDRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+        +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEA-----AKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLI+   +  
Sbjct: 535 VTSHDSSTNGLISFIKQQR 553
>ref|YP_543532.1| glucose-6-phosphate isomerase [Escherichia coli UTI89]
 gb|AAN83417.1|AE016770_217 Glucose-6-phosphate isomerase [Escherichia coli CFT073]
 gb|ABE10001.1| glucose-6-phosphate isomerase [Escherichia coli UTI89]
          Length = 551

 Score = 1103 bits (2855), Expect = 0.0,   Method: Composition-based stats.
 Identities = 316/561 (56%), Positives = 407/561 (72%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   T  A+W  LQK +++  D  I   F  D +R  ++S         ++ + +DYS
Sbjct: 3   MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATF------DDQMLVDYS 56

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGK
Sbjct: 57  KNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGK 116

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 117 DVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 175

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +
Sbjct: 176 NHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----K 230

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++
Sbjct: 231 AAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFD 290

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NFVELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY
Sbjct: 291 NFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAY 350

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+GK V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    
Sbjct: 351 FQQGNMESNGKYVDRNGKVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAI 410

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G R
Sbjct: 411 THNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNR 469

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+  
Sbjct: 470 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDD 529

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             +++HDSSTNGLIN +    
Sbjct: 530 KEISSHDSSTNGLINRYKAWR 550
>emb|CAC83783.1| phosphoglucose isomerase [Bufo melanostictus]
          Length = 553

 Score = 1103 bits (2855), Expect = 0.0,   Method: Composition-based stats.
 Identities = 323/561 (57%), Positives = 410/561 (73%), Gaps = 12/561 (2%)

Query: 48  TTLTSCASWTQLQKLYEQ-YGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
             LTS   + +L K YE  +G   ++K FEAD ER  ++S  ++     E  + +DYSK+
Sbjct: 1   MALTSDPVYQKLAKFYEANHGCLNLRKLFEADKERFNKFSKTLN---TGEGDILVDYSKN 57

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            I +E+   L+ LA  RG+    + +F  E++N TENR VLHIALRNRSN PI VDGKD+
Sbjct: 58  LITEEVIKLLIELARSRGVEAARKRMFSAEKINFTENRAVLHIALRNRSNAPIQVDGKDM 117

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN VL +M++F +KVR+G+WKG++GKAI  VVN+GIGGSDLGP+M TEALKP+S+  
Sbjct: 118 MPEVNAVLGKMKTFCQKVRSGDWKGYSGKAITDVVNVGIGGSDLGPLMVTEALKPYSKGG 177

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
             + FVSN+DGTH+A+ L  ++ E TLFIVASKTFTTQETITNA +A+   L     +  
Sbjct: 178 PRVWFVSNIDGTHMAKTLAELNPETTLFIVASKTFTTQETITNAETAKEWFL-----KAA 232

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            +  +VAKHFVALSTN  KVK+FGID  NMF+FWDWVGGRYS+WSAIGL I + +G++NF
Sbjct: 233 KDPSAVAKHFVALSTNAPKVKDFGIDTANMFEFWDWVGGRYSLWSAIGLSIALHVGFDNF 292

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
            +LL GAH +D HF N P E N+P++LA++GVWYINF+G  T A+LPYDQY+ R  AY Q
Sbjct: 293 EKLLAGAHWMDNHFCNTPLENNIPVILAMLGVWYINFYGCETQALLPYDQYMHRFAAYFQ 352

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q DMESNGKY+T++G  V+  TGP+++GE GTNGQHAFYQLIHQGT +IPCDF+   QSQ
Sbjct: 353 QGDMESNGKYITKTGARVNYNTGPVVWGEPGTNGQHAFYQLIHQGTRMIPCDFMIPAQSQ 412

Query: 467 NKIGD--HHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           N I D  HHKI M+NF AQTEALM GKS  E + EL+A+G  S E +  LLPHK F G R
Sbjct: 413 NPIRDGLHHKILMANFLAQTEALMKGKSTEEAKAELQASG-LSGEALEKLLPHKVFEGNR 471

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N+++   L+P  LGA+IAMYEHK+ VQG +W I+SYDQWGVELGK LAK I P+L   
Sbjct: 472 PTNSIVFGKLSPFILGALIAMYEHKIFVQGVVWDINSYDQWGVELGKQLAKKIEPELESN 531

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             V +HDSSTNGLIN +    
Sbjct: 532 APVTSHDSSTNGLINFYKAHR 552
>ref|NP_290659.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 EDL933]
 ref|NP_313035.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str. Sakai]
 ref|NP_418449.1| glucosephosphate isomerase [Escherichia coli str. K-12 substr.
           MG1655]
 ref|YP_312937.1| glucose-6-phosphate isomerase [Shigella sonnei Ss046]
 ref|YP_410315.1| glucose-6-phosphate isomerase [Shigella boydii Sb227]
 ref|YP_405619.1| glucose-6-phosphate isomerase [Shigella dysenteriae Sd197]
 ref|ZP_00925748.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli 101-1]
 ref|AP_004526.1| glucosephosphate isomerase [Escherichia coli W3110]
 ref|ZP_02739575.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4045]
 ref|ZP_02751760.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4206]
 ref|ZP_02769327.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4115]
 ref|ZP_02775869.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4113]
 ref|ZP_02780180.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4401]
 ref|ZP_02785875.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4501]
 ref|ZP_02791270.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4486]
 ref|ZP_02799367.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4196]
 ref|ZP_02805422.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4076]
 ref|ZP_02809625.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str. EC869]
 ref|ZP_02819451.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4042]
 ref|ZP_02823342.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str. EC508]
 ref|YP_001726931.1| Glucose-6-phosphate isomerase [Escherichia coli ATCC 8739]
 ref|YP_001732802.1| glucosephosphate isomerase [Escherichia coli str. K-12 substr.
           DH10B]
 ref|YP_001882711.1| glucose-6-phosphate isomerase [Shigella boydii CDC 3083-94]
 ref|ZP_02999367.1| glucose-6-phosphate isomerase [Escherichia coli 53638]
 sp|P0A6T1|G6PI_ECOLI Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|P0A6T2|G6PI_ECO57 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q31TX1|G6PI_SHIBS Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q328X7|G6PI_SHIDS Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q3YUW0|G6PI_SHISS Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAG59224.1|AE005635_4 glucosephosphate isomerase [Escherichia coli O157:H7 EDL933]
 gb|AAC43119.1| glucose-6-phosphate isomerase [Escherichia coli]
 gb|AAC76995.1| glucosephosphate isomerase [Escherichia coli str. K-12 substr.
           MG1655]
 dbj|BAB38431.1| glucosephosphate isomerase [Escherichia coli O157:H7 str. Sakai]
 gb|AAZ90702.1| glucosephosphate isomerase [Shigella sonnei Ss046]
 gb|ABB64128.1| glucosephosphate isomerase [Shigella dysenteriae Sd197]
 gb|ABB68487.1| glucosephosphate isomerase [Shigella boydii Sb227]
 dbj|BAE78027.1| glucosephosphate isomerase [Escherichia coli W3110]
 gb|ACA79604.1| Glucose-6-phosphate isomerase [Escherichia coli ATCC 8739]
 gb|ACB05024.1| glucosephosphate isomerase [Escherichia coli str. K-12 substr.
           DH10B]
 gb|ACD08826.1| glucose-6-phosphate isomerase [Shigella boydii CDC 3083-94]
 gb|EDU33726.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4196]
 gb|EDU53151.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4113]
 gb|EDU62399.1| glucose-6-phosphate isomerase [Escherichia coli 53638]
 gb|EDU70767.1| glucose-6-phosphate isomerase [Escherichia coli O157:H7 str.
           EC4076]
          Length = 549

 Score = 1103 bits (2855), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/561 (56%), Positives = 406/561 (72%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   T  A+W  LQK +++  D  I   F  D +R  ++S         ++ + +DYS
Sbjct: 1   MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATF------DDQMLVDYS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGK
Sbjct: 55  KNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +
Sbjct: 174 NHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----K 228

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++
Sbjct: 229 AAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFD 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NFVELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY
Sbjct: 289 NFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G R
Sbjct: 409 THNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+  
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             +++HDSSTNGLIN +    
Sbjct: 528 KEISSHDSSTNGLINRYKAWR 548
>ref|ZP_00711964.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli B171]
 ref|ZP_00715960.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli B7A]
 ref|ZP_00722553.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli E110019]
 ref|ZP_00730314.1| COG0166: Glucose-6-phosphate isomerase [Escherichia coli E22]
 ref|YP_001465522.1| glucose-6-phosphate isomerase [Escherichia coli E24377A]
 ref|YP_001460811.1| glucose-6-phosphate isomerase [Escherichia coli HS]
 sp|A7ZUP3|G6PI_ECO24 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|A8A7C4|G6PI_ECOHS Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|ABV08428.1| glucose-6-phosphate isomerase [Escherichia coli HS]
 gb|ABV16980.1| glucose-6-phosphate isomerase [Escherichia coli E24377A]
          Length = 549

 Score = 1103 bits (2853), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/561 (56%), Positives = 405/561 (72%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   T  A+W  LQK +++  D  I   F  D +R  ++S          + + +DYS
Sbjct: 1   MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATF------GDQMLVDYS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGK
Sbjct: 55  KNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +
Sbjct: 174 NHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----K 228

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++
Sbjct: 229 AAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFD 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NFVELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY
Sbjct: 289 NFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G R
Sbjct: 409 THNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+  
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             +++HDSSTNGLIN +    
Sbjct: 528 KEISSHDSSTNGLINRYKAWR 548
>ref|YP_691477.1| glucose-6-phosphate isomerase [Shigella flexneri 5 str. 8401]
 sp|Q0SXP3|G6PI_SHIF8 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|ABF06172.1| glucosephosphate isomerase [Shigella flexneri 5 str. 8401]
          Length = 549

 Score = 1103 bits (2853), Expect = 0.0,   Method: Composition-based stats.
 Identities = 314/561 (55%), Positives = 406/561 (72%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   T  A+W  LQK +++  D  I   F  D +R  ++S   +      + + +DYS
Sbjct: 1   MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFN------DQMLVDYS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGK
Sbjct: 55  KNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHI+EVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +
Sbjct: 174 NHLNMHFVSNVDGTHISEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----K 228

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++
Sbjct: 229 AAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFD 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NFVELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY
Sbjct: 289 NFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G R
Sbjct: 409 THNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+  
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             +++HDSSTNGLIN +    
Sbjct: 528 KEISSHDSSTNGLINRYKAWR 548
>ref|NP_838787.1| glucose-6-phosphate isomerase [Shigella flexneri 2a str. 2457T]
 ref|NP_709894.2| glucose-6-phosphate isomerase [Shigella flexneri 2a str. 301]
 sp|Q83IN9|G6PI_SHIFL Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAP18598.1| glucosephosphate isomerase [Shigella flexneri 2a str. 2457T]
 gb|AAN45601.2| glucosephosphate isomerase [Shigella flexneri 2a str. 301]
          Length = 549

 Score = 1103 bits (2853), Expect = 0.0,   Method: Composition-based stats.
 Identities = 314/561 (55%), Positives = 406/561 (72%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   T  A+W  LQK +++  D  I   F  D +R  ++S         ++ + +DYS
Sbjct: 1   MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATF------DDQMLVDYS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGK
Sbjct: 55  KNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHI+EVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +
Sbjct: 174 NHLNMHFVSNVDGTHISEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----K 228

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++
Sbjct: 229 AAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFD 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NFVELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY
Sbjct: 289 NFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G R
Sbjct: 409 THNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+  
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             +++HDSSTNGLIN +    
Sbjct: 528 KEISSHDSSTNGLINRYKAWR 548
>ref|NP_997475.1| glucose phosphate isomerase [Rattus norvegicus]
 gb|AAH62005.1| Glucose phosphate isomerase [Rattus norvegicus]
          Length = 558

 Score = 1101 bits (2850), Expect = 0.0,   Method: Composition-based stats.
 Identities = 318/559 (56%), Positives = 418/559 (74%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQY-GDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L + +     +  +++ FEAD ER   +S+ ++    +   + LDYSK+ +
Sbjct: 4   LTRNPEFQKLLEWHRANSANLKLRELFEADPERFNHFSLNLN---TNHGHILLDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N+TE+R VLH+ALRNRSNR I +DGKDVMP
Sbjct: 61  NKEVLHMLVDLAKSRGVEAARDNMFSGLKINSTEDRAVLHVALRNRSNRSIMMDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VNKVLD+M+SF ++VR+G+WKG+TGKAI  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNKVLDKMKSFCQRVRSGDWKGYTGKAITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L +++ E++LFI+ASKTFTTQETITNA +A+   L     +   +
Sbjct: 181 VWFVSNIDGTHIAKTLANLNPESSLFIIASKTFTTQETITNAETAKEWFL-----QAAKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTDKVKEFGIDPKNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P ++N P+LLAL+G+WYINF+G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFMKTPLDKNAPVLLALLGIWYINFYGCETHAMLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDYQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKSP E R+EL+AAG +S E++  LLPHK F G RP+
Sbjct: 416 IRNGLHHKILLANFLAQTEALMKGKSPEEARKELQAAG-KSPEELEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSSA 534

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLI       
Sbjct: 535 VTSHDSSTNGLIGFIKLQR 553
>prf||1405328A phosphohexose isomerase
          Length = 558

 Score = 1101 bits (2849), Expect = 0.0,   Method: Composition-based stats.
 Identities = 314/559 (56%), Positives = 413/559 (73%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQY-GDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L + +     +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTEDRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+ +SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKNKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+        +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEA-----AKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKSTEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLI+   +  
Sbjct: 535 VTSHDSSTNGLISFIKQQR 553
>emb|CAA33268.1| unnamed protein product [Escherichia coli]
          Length = 549

 Score = 1101 bits (2849), Expect = 0.0,   Method: Composition-based stats.
 Identities = 314/561 (55%), Positives = 406/561 (72%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   T  A+W  LQK +++  D  I   F  D +R  ++S         ++ + +DYS
Sbjct: 1   MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATF------DDQMLVDYS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGK
Sbjct: 55  KNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +
Sbjct: 174 NHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----K 228

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++
Sbjct: 229 AAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFD 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NFVELL+GAH +D+HF+  P E+N+P+L+AL+G+WY NFFGA T AILPYDQY+ R  AY
Sbjct: 289 NFVELLSGAHAMDKHFSTTPAEKNLPVLVALIGIWYNNFFGAETEAILPYDQYMHRFAAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G R
Sbjct: 409 THNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+  
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             +++HDSSTNGLIN +    
Sbjct: 528 KEISSHDSSTNGLINRYKAWR 548
>pdb|1U0E|A Chain A, Crystal Structure Of Mouse Phosphoglucose Isomerase
 pdb|1U0E|B Chain B, Crystal Structure Of Mouse Phosphoglucose Isomerase
 pdb|1U0F|A Chain A, Crystal Structure Of Mouse Phosphoglucose Isomerase In
           Complex With Glucose 6-Phosphate
 pdb|1U0F|B Chain B, Crystal Structure Of Mouse Phosphoglucose Isomerase In
           Complex With Glucose 6-Phosphate
 pdb|1U0G|A Chain A, Crystal Structure Of Mouse Phosphoglucose Isomerase In
           Complex With Erythrose 4-Phosphate
 pdb|1U0G|B Chain B, Crystal Structure Of Mouse Phosphoglucose Isomerase In
           Complex With Erythrose 4-Phosphate
          Length = 564

 Score = 1101 bits (2848), Expect = 0.0,   Method: Composition-based stats.
 Identities = 314/559 (56%), Positives = 413/559 (73%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQY-GDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L + +     +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TE+R VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTEDRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+        +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEA-----AKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NM +FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMLEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLI+   +  
Sbjct: 535 VTSHDSSTNGLISFIKQQR 553
>dbj|BAE23502.1| unnamed protein product [Mus musculus]
          Length = 558

 Score = 1101 bits (2848), Expect = 0.0,   Method: Composition-based stats.
 Identities = 317/559 (56%), Positives = 415/559 (74%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQY-GDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L + +     +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TENR VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+        +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEA-----AKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+LVQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKILVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLI+   +  
Sbjct: 535 VTSHDSSTNGLISFIKQQR 553
>dbj|BAE21866.1| unnamed protein product [Mus musculus]
          Length = 558

 Score = 1101 bits (2848), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/559 (56%), Positives = 413/559 (73%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQY-GDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L + +     +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TENR VLH+ALRNRSN PI VDGKDV P
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVKP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+        +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEA-----AKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLI+   +  
Sbjct: 535 VTSHDSSTNGLISFIKQQR 553
>dbj|BAE35416.1| unnamed protein product [Mus musculus]
          Length = 558

 Score = 1101 bits (2848), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/559 (56%), Positives = 413/559 (73%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQY-GDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L + +     +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TENR VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGTHIA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+        +
Sbjct: 181 VWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEA-----AKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P  +N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLGKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLI+   +  
Sbjct: 535 VTSHDSSTNGLISFIKQQR 553
>dbj|BAE22329.1| unnamed protein product [Mus musculus]
          Length = 558

 Score = 1101 bits (2848), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/559 (56%), Positives = 413/559 (73%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQY-GDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LT    + +L + +     +  +++ FEAD ER   +S+ ++    +   + +DYSK+ +
Sbjct: 4   LTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLN---TNHGHILVDYSKNLV 60

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N E+   L+ LA+ RG+     ++F G ++N TENR VLH+ALRNRSN PI VDGKDVMP
Sbjct: 61  NKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMP 120

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN+VLD+M+SF ++VR+G+WKG+TGK+I  ++NIGIGGSDLGP+M TEALKP+S+    
Sbjct: 121 EVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPR 180

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
           + FVSN+DGT IA+ L S+  E +LFI+ASKTFTTQETITNA +A+   L+        +
Sbjct: 181 VWFVSNIDGTRIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEA-----AKD 235

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
             +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G+++F +
Sbjct: 236 PSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQ 295

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D+HF   P E+N P+LLAL+G+WYIN +G  THA+LPYDQY+ R  AY QQ 
Sbjct: 296 LLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQG 355

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ 
Sbjct: 356 DMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHP 415

Query: 469 I--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I  G HHKI ++NF AQTEALM GK P E R+EL+AAG +S E +  LLPHK F G RP+
Sbjct: 416 IRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAG-KSPEDLEKLLPHKVFEGNRPT 474

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++   LTP  LGA+IAMYEHK+ VQG +W I+S+DQWGVELGK LAK I P+L     
Sbjct: 475 NSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSA 534

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HDSSTNGLI+   +  
Sbjct: 535 VTSHDSSTNGLISFIKQQR 553
>ref|YP_001008017.1| glucose-6-phosphate isomerase [Yersinia enterocolitica subsp.
           enterocolitica 8081]
 sp|A1JRV9|G6PI_YERE8 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 emb|CAL13891.1| glucose-6-phosphate isomerase [Yersinia enterocolitica subsp.
           enterocolitica 8081]
          Length = 548

 Score = 1100 bits (2846), Expect = 0.0,   Method: Composition-based stats.
 Identities = 319/561 (56%), Positives = 399/561 (71%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   +  A+W  LQ+ +EQ  D  I   F  D +R  ++S         ++ + +D+S
Sbjct: 1   MKNINPSQTAAWKALQQHFEQMKDVTISSLFAKDDQRFNQFSATF------DDQMLVDFS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I  E    L  LA+E  +   ++++F GE++N TE+R VLHIALRNRSN PI VDGK
Sbjct: 55  KNRITRETMEKLQALAKETDLAGAIKAMFSGEKINRTEDRAVLHIALRNRSNTPIVVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL +M+ F ++V  GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLAKMKQFCDRVIGGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAE LK ++ E TLF+VASKTFTTQET+TNA SAR   L      
Sbjct: 174 NHLNMHFVSNVDGTHIAETLKPLNPETTLFLVASKTFTTQETMTNAHSARDWFLS----- 228

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I +S+G+E
Sbjct: 229 TASDEKHVAKHFAALSTNAKAVGEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSVGFE 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NF +LL+GAH +D+HFA  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R PAY
Sbjct: 289 NFEQLLSGAHAMDKHFAETPAEKNLPILLALIGIWYNNFFGAETEAILPYDQYMHRFPAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R GK V   TGPII+GE GTNGQHAFYQLIHQGT L+PCDFI    
Sbjct: 349 FQQGNMESNGKYVGRDGKPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLVPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           S N + DHH   +SNFFAQTEAL  GKS +EV  E  A G ++ E++  + P K F G R
Sbjct: 409 SHNPLSDHHAKLLSNFFAQTEALAFGKSLAEVEAEFAATG-KTPEQVAHVAPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I S+DQWGVELGK LA  ILP+L   
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIYSFDQWGVELGKQLANRILPELAGD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
            +V +HDSSTN LIN F    
Sbjct: 528 EKVTSHDSSTNALINRFKSWR 548
>ref|NP_001006128.1| glucose phosphate isomerase [Gallus gallus]
 emb|CAG30950.1| hypothetical protein [Gallus gallus]
          Length = 553

 Score = 1099 bits (2843), Expect = 0.0,   Method: Composition-based stats.
 Identities = 320/561 (57%), Positives = 409/561 (72%), Gaps = 12/561 (2%)

Query: 48  TTLTSCASWTQLQKLYEQYGD-EPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
             L++   + +L + ++       +++ FEAD +R  ++S+ ++    D   + LDYSK+
Sbjct: 1   MPLSADPHFKKLLEWHKANASKLVLRQLFEADKDRFHKFSLTLN---TDHGDILLDYSKN 57

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            + +E+   L+ LA+ RG+    + +F GE++N TENR VLHIALRNRSN PI VDGKDV
Sbjct: 58  LVTEEVMKMLIELAKSRGVESARERMFSGEKINFTENRAVLHIALRNRSNTPILVDGKDV 117

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           +P VNKVLD+M+ F +KVR+GEWKG+TGKAI  VVNIGIGGSDLGP+M TE LKP+S+  
Sbjct: 118 VPEVNKVLDKMKHFCQKVRSGEWKGYTGKAITDVVNIGIGGSDLGPLMVTEVLKPYSKGG 177

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
             + FVSN+DGTHIA+ L  +  E TLFI+ASKTFTTQETITNA++A+   L        
Sbjct: 178 PRVWFVSNIDGTHIAKTLAELHPETTLFIIASKTFTTQETITNAVTAKEWFL-----HAA 232

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            +  +VAKHFVALSTN  KVKEFGID ENMF+FWDWVGGRYS+WSAIGL I + IG++NF
Sbjct: 233 KDPSAVAKHFVALSTNGPKVKEFGIDTENMFEFWDWVGGRYSLWSAIGLSIALHIGFDNF 292

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
             LL G H +D+HF  AP E+NVP+LLA++GVWYIN +G  THA+LPYDQY+ R  AY Q
Sbjct: 293 ESLLAGGHWMDKHFHTAPLEKNVPVLLAMLGVWYINCYGCETHALLPYDQYMHRFAAYFQ 352

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q DMESNGKY+T+ G  V   TGPI++GE  TNGQHAFYQLIHQGT +IPCDF+  +Q+Q
Sbjct: 353 QGDMESNGKYITKKGSRVDYNTGPIVWGEPDTNGQHAFYQLIHQGTRMIPCDFMIPVQTQ 412

Query: 467 NKI--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + +  G HHKI ++NF AQTEALM GK+  E R+EL+AAG  S + +  LLPHK F G R
Sbjct: 413 HPVRNGLHHKILLANFLAQTEALMKGKTADEARKELQAAG-LSGDALEKLLPHKVFEGNR 471

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N+++   L P  LGAIIAMYEHK+ VQG +W I+SYDQWGVELGK LAK I P+L   
Sbjct: 472 PTNSIMFTKLNPFTLGAIIAMYEHKIFVQGVVWDINSYDQWGVELGKQLAKKIEPELESD 531

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             V +HDSSTNGLI+   +  
Sbjct: 532 APVTSHDSSTNGLISFIKKHR 552
>ref|NP_407169.1| glucose-6-phosphate isomerase [Yersinia pestis CO92]
 ref|NP_667368.1| glucose-6-phosphate isomerase [Yersinia pestis KIM]
 ref|YP_072131.1| glucose-6-phosphate isomerase [Yersinia pseudotuberculosis IP
           32953]
 ref|YP_649940.1| glucose-6-phosphate isomerase [Yersinia pestis Antiqua]
 ref|YP_645956.1| glucose-6-phosphate isomerase [Yersinia pestis Nepal516]
 ref|YP_001161574.1| glucose-6-phosphate isomerase [Yersinia pestis Pestoides F]
 ref|YP_001399296.1| glucose-6-phosphate isomerase [Yersinia pseudotuberculosis IP
           31758]
 ref|ZP_02022354.1| glucose-6-phosphate isomerase [Yersinia pestis CA88-4125]
 ref|YP_001608219.1| glucose-6-phosphate isomerase [Yersinia pestis Angola]
 ref|ZP_02223759.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Orientalis
           str. F1991016]
 ref|ZP_02228336.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Orientalis
           str. IP275]
 ref|ZP_02232924.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Antiqua str.
           E1979001]
 ref|ZP_02239503.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Antiqua str.
           B42003004]
 ref|ZP_02306734.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Antiqua str.
           UG05-0454]
 ref|ZP_02312504.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Orientalis
           str. MG05-1020]
 ref|ZP_02318644.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Mediaevalis
           str. K1973002]
 ref|ZP_02333066.1| glucose-6-phosphate isomerase [Yersinia pestis FV-1]
 ref|YP_001719131.1| Glucose-6-phosphate isomerase [Yersinia pseudotuberculosis YPIII]
 ref|YP_001874245.1| phosphoglucose isomerase (PGI) [Yersinia pseudotuberculosis PB1/+]
 sp|Q1CC27|G6PI_YERPA Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q1CNS4|G6PI_YERPN Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|A4TH39|G6PI_YERPP Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|A7FDG8|G6PI_YERP3 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q8ZAS2|G6PI_YERPE Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|Q664W9|G6PI_YERPS Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|AAM83619.1|AE013604_2 glucosephosphate isomerase [Yersinia pestis KIM]
 emb|CAH22887.1| glucose-6-phosphate isomerase [Yersinia pseudotuberculosis IP
           32953]
 gb|ABG16356.1| glucose-6-phosphate isomerase [Yersinia pestis Nepal516]
 gb|ABG11995.1| glucose-6-phosphate isomerase [Yersinia pestis Antiqua]
 emb|CAL22305.1| glucose-6-phosphate isomerase [Yersinia pestis CO92]
 gb|ABP38601.1| glucose-6-phosphate isomerase [Yersinia pestis Pestoides F]
 gb|EDM38971.1| glucose-6-phosphate isomerase [Yersinia pestis CA88-4125]
 gb|ABS48623.1| glucose-6-phosphate isomerase [Yersinia pseudotuberculosis IP
           31758]
 gb|ABX86967.1| glucose-6-phosphate isomerase [Yersinia pestis Angola]
 gb|EDR30926.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Orientalis
           str. IP275]
 gb|EDR37384.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Orientalis
           str. F1991016]
 gb|EDR41363.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Antiqua str.
           E1979001]
 gb|EDR49889.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Antiqua str.
           B42003004]
 gb|EDR57578.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Orientalis
           str. MG05-1020]
 gb|EDR60667.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Antiqua str.
           UG05-0454]
 gb|EDR63945.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Mediaevalis
           str. K1973002]
 gb|ACA66678.1| Glucose-6-phosphate isomerase [Yersinia pseudotuberculosis YPIII]
 gb|ACC90788.1| phosphoglucose isomerase (PGI) [Yersinia pseudotuberculosis PB1/+]
          Length = 548

 Score = 1098 bits (2842), Expect = 0.0,   Method: Composition-based stats.
 Identities = 318/561 (56%), Positives = 398/561 (70%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   +  A+W  LQ+ +EQ  D  I   F  D +R  R+S         ++ + +D+S
Sbjct: 1   MKNINPSQTAAWKALQQHFEQMKDVTISSLFAKDDQRFNRFSATF------DDQMLVDFS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I  E    L  LA+E  +   ++S+F GE++N TE+R VLHIALRNRSN PI VDGK
Sbjct: 55  KNRITSETLEKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHIALRNRSNTPIVVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL +M+ F ++V +G+WKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLAKMKQFCDRVISGDWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAE LK ++ E TLF+VASKTFTTQET+TNA SAR   L      
Sbjct: 174 NHLNMHFVSNVDGTHIAEALKPLNPETTLFLVASKTFTTQETMTNAHSARDWFLSA---- 229

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              +   VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I +S+G+E
Sbjct: 230 -AGDPAHVAKHFAALSTNAKAVGEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSVGFE 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           +F +LL+GAH +D+HFA  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R PAY
Sbjct: 289 HFEQLLSGAHAMDKHFAETPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFPAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT LIPCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGHPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           S N + DHH   +SNFFAQTEAL  GKS  +V  E  AAG ++ E++  + P K F G R
Sbjct: 409 SHNPLSDHHAKLLSNFFAQTEALAFGKSLEDVEAEFAAAG-KTPEQVAHVAPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L   
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIYTFDQWGVELGKQLANRILPELADD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             V +HDSSTN LIN F    
Sbjct: 528 QEVTSHDSSTNALINRFKNWR 548
>dbj|BAF91562.1| phosphoglucose isomerase [Lepisosteus osseus]
          Length = 555

 Score = 1097 bits (2839), Expect = 0.0,   Method: Composition-based stats.
 Identities = 331/559 (59%), Positives = 416/559 (74%), Gaps = 12/559 (2%)

Query: 50  LTSCASWTQLQKLYEQ-YGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHI 108
           LTS  S+ +L++ Y    G   +++ FEAD  R  ++S  ++    D+  + +D+SK+ I
Sbjct: 5   LTSDPSFQKLEQWYRANAGSLNMRQMFEADQGRFGKFSTTLN---TDDGDILVDFSKNLI 61

Query: 109 NDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMP 168
           N+E+   L  LA  RG+ +  + +F GE++N TENR VLHIALRNRSN PI+V GKDVMP
Sbjct: 62  NEEVMKMLFDLARSRGVEEAREKMFTGEKINFTENRAVLHIALRNRSNSPIHVGGKDVMP 121

Query: 169 AVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLS 228
            VN VL++M++F +KVR+GEWKG+TGKAI  +VNIGIGGSDLGP+M TEALKP+S+    
Sbjct: 122 EVNSVLEKMKAFCQKVRSGEWKGYTGKAITDIVNIGIGGSDLGPLMVTEALKPYSKGGPR 181

Query: 229 LHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDE 288
             FVSN+DGTH+A+ L  ++ E TLFI+ASKTFTTQETITNA SA+  LL         +
Sbjct: 182 AWFVSNIDGTHMAKTLAELNPETTLFIIASKTFTTQETITNAESAKEWLLQK-----AGD 236

Query: 289 KGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVE 348
           K +VAKHFVALSTN  KVK+FGID  NMF+FWDWVGGRYS+WSAIGL I + IG+ENF  
Sbjct: 237 KSAVAKHFVALSTNAPKVKDFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALHIGFENFER 296

Query: 349 LLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQL 408
           LL+GAH +D HF  AP E+NVP+LLAL+GVWYINFF A THA+LPYDQY+ R  AY QQ 
Sbjct: 297 LLSGAHWMDNHFRTAPLEKNVPVLLALLGVWYINFFQAETHALLPYDQYMHRFAAYFQQG 356

Query: 409 DMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNK 468
           DMESNGKY+T  G  V+  TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +QSQ+ 
Sbjct: 357 DMESNGKYITSKGSRVNYHTGPIVWGEPGTNGQHAFYQLIHQGTRMIPCDFLIPVQSQHP 416

Query: 469 IGD--HHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPS 526
           I +  HHKI ++NF AQTEALM GK+  E R+ELE AG  S E +  LLPHK F G +P+
Sbjct: 417 IRNNLHHKILLANFLAQTEALMKGKTTEEARKELEGAG-MSGEPLEKLLPHKVFEGNKPT 475

Query: 527 NTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMR 586
           N+++ K LTP  LGA+IAMYEHK+ +QG IW I+SYDQWGVELGK LAK I P+L+    
Sbjct: 476 NSIVFKKLTPFMLGALIAMYEHKIFMQGVIWEINSYDQWGVELGKQLAKKIEPELQDAGE 535

Query: 587 VNNHDSSTNGLINMFNELS 605
           V +HD STNGLI+   + S
Sbjct: 536 VTSHDGSTNGLISFIKKNS 554
>ref|ZP_02903962.1| glucose-6-phosphate isomerase [Escherichia albertii TW07627]
 gb|EDS90497.1| glucose-6-phosphate isomerase [Escherichia albertii TW07627]
          Length = 549

 Score = 1097 bits (2839), Expect = 0.0,   Method: Composition-based stats.
 Identities = 313/561 (55%), Positives = 405/561 (72%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   T  A+W  LQK +++  D  I   F  D +R  ++S         ++ + +DYS
Sbjct: 1   MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATF------DDQMLVDYS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I +E    L  LA+E  +   ++S+F GE++N TENR VLH+ALRNRSN PI VDGK
Sbjct: 55  KNRITEETLAKLQDLAKECDLTGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL++M++FSE + +GEWKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAEVLK ++ E TLF+VASKTFTTQET+TNA SAR   L     +
Sbjct: 174 NHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFL-----K 228

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++SIG++
Sbjct: 229 AAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFD 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NF+ELL+GAH +D+HF+    E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY
Sbjct: 289 NFIELLSGAHAMDKHFSTTSAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT ++PCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + N + DHH+  +SNFFAQTEAL  GKS   V +E    G +    ++ ++P K F G R
Sbjct: 409 THNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQG-KDPATLDYVVPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L+  
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             +++HDSSTNGLIN +    
Sbjct: 528 KAISSHDSSTNGLINRYKAWR 548
>sp|P50309|G6PI_CRIGR Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 emb|CAA86031.1| glucose phosphate isomerase [Cricetulus griseus]
          Length = 558

 Score = 1097 bits (2838), Expect = 0.0,   Method: Composition-based stats.
 Identities = 317/563 (56%), Positives = 412/563 (73%), Gaps = 12/563 (2%)

Query: 48  TTLTSCASWTQLQK-LYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
           T+LT    + +LQ    +   D  ++  F+AD ER   +S+ ++        + +DYSK+
Sbjct: 2   TSLTQNRYFQKLQDWHRDNSADINLRSLFDADPERFNNFSLNLN---TTHGHILVDYSKN 58

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            +N E+   L+ LA  RG+     ++F G ++N TE+R VLH+ALRNRSN PI VD +DV
Sbjct: 59  LVNKEVMQMLVDLARSRGVETMRDNMFSGVKINYTEDRAVLHVALRNRSNSPIVVDSRDV 118

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN+VL++MRSF ++VR+GEWKG++GK I  +VNIGIGGSDLGP+M TEALKP++   
Sbjct: 119 MPEVNRVLEKMRSFCQRVRSGEWKGYSGKPITDIVNIGIGGSDLGPLMVTEALKPYASGG 178

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
             + FVSN+DGTHIA+ L ++  E++LFIVASKTFTTQETITNA +A+   L   R    
Sbjct: 179 PRIWFVSNIDGTHIAKTLANLTPESSLFIVASKTFTTQETITNAETAKEWFLGASR---- 234

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            +  +VAKHF+ALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + IG++NF
Sbjct: 235 -DPSTVAKHFIALSTNTSKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHIGFDNF 293

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
            +LL+GAH +D+HF   P E+N P+LLAL+G+WYINF+G  THA+LPYDQY+ R  AY Q
Sbjct: 294 EQLLSGAHWMDQHFRKTPLEKNAPVLLALLGIWYINFYGCETHALLPYDQYMHRFAAYFQ 353

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q DMESNGK +TRSG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q
Sbjct: 354 QGDMESNGKSITRSGTRVDHHTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQ 413

Query: 467 NKI--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + I  G HHKI ++NF AQTEALM GKS  E ++EL+AAG +S E +  LLPHK F G R
Sbjct: 414 HPIRKGLHHKILLANFLAQTEALMKGKSNEEAKKELQAAG-KSPEDLEKLLPHKVFEGNR 472

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N+++   LTP  LGA+IA+YEHK+ VQG IW I+S+DQWGVELGK LAK+I P+L   
Sbjct: 473 PTNSIVFTKLTPFILGALIALYEHKIFVQGVIWDINSFDQWGVELGKQLAKNIEPELDGS 532

Query: 585 MRVNNHDSSTNGLINMFNELSHL 607
             V +HDSSTNGLI    +   +
Sbjct: 533 APVTSHDSSTNGLIKFIKQQRDI 555
>gb|AAH83507.1| Glucose phosphate isomerase a [Danio rerio]
          Length = 553

 Score = 1096 bits (2837), Expect = 0.0,   Method: Composition-based stats.
 Identities = 325/562 (57%), Positives = 420/562 (74%), Gaps = 12/562 (2%)

Query: 48  TTLTSCASWTQLQKLYEQ-YGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
             L +  ++ +L++ Y+   G+  +++ FEAD++R  ++S+++   S D+  L LD+SK+
Sbjct: 1   MGLNNDPNFIKLEQWYKSSAGNLNMRQMFEADADRFNKFSLQL---STDDGDLLLDFSKN 57

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            IN+++   L  +A   G+    + +F GE++N TE R VLH ALRNRSN PI VDGKDV
Sbjct: 58  LINEDVMSLLFDMARSVGVEAAREQMFAGEKINFTEGRAVLHTALRNRSNTPIMVDGKDV 117

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN+VL+QM+SF  KVR+G WKG +GK+I  VVNIGIGGSDLGP+M TEALKP+S+  
Sbjct: 118 MPEVNRVLEQMKSFCHKVRSGAWKGFSGKSITDVVNIGIGGSDLGPLMVTEALKPYSKGG 177

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
            ++ FVSN+DGTH+A+ L  ++ E TLFI+ASKTFTTQETITNA +AR   L     +  
Sbjct: 178 PNVWFVSNIDGTHMAKTLAQLNAETTLFIIASKTFTTQETITNAETAREWFL-----QAA 232

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            +K +VAKHFVALSTN  KVKEFGID  NMF+FWDWVGGRYS+WSAIGL I + IG++NF
Sbjct: 233 KDKSAVAKHFVALSTNAPKVKEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALHIGFDNF 292

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
            +LL+GAH +D HF +AP EQN P++LAL+GVWY+NFF A THA+LPYDQY+ R  AY Q
Sbjct: 293 EQLLSGAHWMDNHFRSAPLEQNAPVILALLGVWYVNFFQAETHALLPYDQYMHRFAAYFQ 352

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q DMESNGKY+T+SG  V+  TGPI++GE GTNGQHAFYQLIHQGT LIP DF+   QSQ
Sbjct: 353 QGDMESNGKYITKSGTRVNYHTGPIVWGEPGTNGQHAFYQLIHQGTRLIPADFLIPAQSQ 412

Query: 467 NKIGD--HHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + I D  HHKI M+NF AQTEALM GK+  E ++EL+A+G  S + +  LLPHK F G +
Sbjct: 413 HPIRDNLHHKILMANFLAQTEALMRGKTSDEAKKELQASG-LSGDSLEKLLPHKVFQGNK 471

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           PSN+++ K LTP  LGA++AMYEHK+ VQG +W I+SYDQWGVELGK LAK I P+L+  
Sbjct: 472 PSNSIIFKKLTPFMLGALVAMYEHKIFVQGVMWNINSYDQWGVELGKQLAKKIEPELQDD 531

Query: 585 MRVNNHDSSTNGLINMFNELSH 606
             V++HDSSTNGLI  F +   
Sbjct: 532 AEVHSHDSSTNGLIGFFKKNRS 553
>ref|NP_994374.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Microtus str.
           91001]
 gb|AAS63251.1| glucose-6-phosphate isomerase [Yersinia pestis biovar Microtus str.
           91001]
          Length = 548

 Score = 1096 bits (2836), Expect = 0.0,   Method: Composition-based stats.
 Identities = 317/561 (56%), Positives = 398/561 (70%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   +  A+W  LQ+ +EQ  D  I   F  D +R  R+S         ++ + +D+S
Sbjct: 1   MKNINPSQTAAWKALQQHFEQMKDVTISSLFAKDDQRFNRFSATF------DDQMLVDFS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I  E    L  LA+E  +   ++S+F GE++N TE+R VLHIALRNRSN PI VDGK
Sbjct: 55  KNRITSETLEKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHIALRNRSNTPIVVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL +M+ F ++V +G+WKG+TGKAI  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLAKMKQFCDRVISGDWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAE LK ++ E TLF+VASKTFTTQET+TNA SAR   L      
Sbjct: 174 NHLNMHFVSNVDGTHIAEALKPLNPETTLFLVASKTFTTQETMTNAHSARDWFLSA---- 229

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              +   VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I +S+G+E
Sbjct: 230 -AGDPAHVAKHFAALSTNAKAVGEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSVGFE 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           +F +LL+G+H +D+HFA  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R PAY
Sbjct: 289 HFEQLLSGSHAMDKHFAETPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFPAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT LIPCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGHPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           S N + DHH   +SNFFAQTEAL  GKS  +V  E  AAG ++ E++  + P K F G R
Sbjct: 409 SHNPLSDHHAKLLSNFFAQTEALAFGKSLEDVEAEFAAAG-KTPEQVAHVAPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QG I  I ++DQWGVELGK LA  ILP+L   
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGVILNIYTFDQWGVELGKQLANRILPELADD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             V +HDSSTN LIN F    
Sbjct: 528 QEVTSHDSSTNALINRFKNWR 548
>ref|YP_001436210.1| hypothetical protein ESA_00069 [Enterobacter sakazakii ATCC
           BAA-894]
 sp|A7MPC2|G6PI_ENTS8 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|ABU75374.1| hypothetical protein ESA_00069 [Enterobacter sakazakii ATCC
           BAA-894]
          Length = 549

 Score = 1096 bits (2836), Expect = 0.0,   Method: Composition-based stats.
 Identities = 312/561 (55%), Positives = 405/561 (72%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   T  ++W  LQ  ++   +  + + F  D++R  ++S   +      + + +DYS
Sbjct: 1   MKNINPTQTSAWQALQNHFDAMKEVTLAELFAKDADRFGKFSATFN------DQMLVDYS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I +E    LL LA+E  +   ++S+F GE++N TE+R VLH+ALRNRSN PI VDGK
Sbjct: 55  KNRITEETLSKLLDLAKETDLAGAIKSMFSGEKINRTEDRAVLHVALRNRSNTPILVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL++M+ FSE + +GEWKG+TGK I  VVNIGIGGSDLGP M TEAL+P+ +
Sbjct: 115 DVMPEVNAVLEKMKKFSEAIISGEWKGYTGKPITDVVNIGIGGSDLGPFMVTEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAEVLK ++ E+TLF+VASKTFTTQET+TNA SAR   L     +
Sbjct: 174 NHLNMHFVSNVDGTHIAEVLKKVNPESTLFLVASKTFTTQETMTNAHSARDWFL-----K 228

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V EFGID  NMF+FWDWVGGRYS+WSAIGL I++S+GY+
Sbjct: 229 TAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIILSVGYD 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NFVELL+GAH +D+HF+  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY
Sbjct: 289 NFVELLSGAHEMDKHFSTTPFEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT L+PCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGNAVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLVPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + N + DHH+  +SNFFAQTEAL  GKS   V +E    G +   ++  ++P K F G R
Sbjct: 409 THNPLSDHHQKLLSNFFAQTEALAFGKSRDVVEQEFRDQG-KDPAQLENVVPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LGA+IA+YEHK+  QGAI  I ++DQWGVELGK LA  ILP+L   
Sbjct: 468 PTNSILLREITPFSLGALIALYEHKIFTQGAILNIFTFDQWGVELGKQLANRILPELGDN 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             + +HDSSTNGLIN +    
Sbjct: 528 KEIASHDSSTNGLINRYKAWR 548
>ref|XP_001490657.1| PREDICTED: similar to Glucose phosphate isomerase [Equus caballus]
          Length = 554

 Score = 1096 bits (2836), Expect = 0.0,   Method: Composition-based stats.
 Identities = 318/559 (56%), Positives = 409/559 (73%), Gaps = 16/559 (2%)

Query: 51  TSCASWTQLQKLYEQYG-DEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKSHIN 109
           T    + +L++ + ++G +  +++HFE    R    ++       +   + +DYSK+ + 
Sbjct: 5   TQNPQFQKLREWHREHGAELNLRRHFE--RTRSAHLTLN-----TNHGHILVDYSKNLVT 57

Query: 110 DEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDVMPA 169
           + +   L+ LA+ RG+    + +F GE++N TENR VLH+ALRNRSN PI VDGKDVMP 
Sbjct: 58  ESVMQMLVDLAKSRGVEAARERMFSGEKINFTENRAVLHVALRNRSNTPILVDGKDVMPE 117

Query: 170 VNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRDLSL 229
           VNKVL++M+SF ++VR G+WKG+TGK I  V+NIGIGGSDLGP+M TEALKP+S     +
Sbjct: 118 VNKVLEKMKSFCQQVRNGDWKGYTGKPITDVINIGIGGSDLGPLMVTEALKPYSSGGPRV 177

Query: 230 HFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGIDEK 289
            FVSN+DGTHIA+ L S++ E+ LFI+ASKTFTTQETITNA +A+  LL         + 
Sbjct: 178 WFVSNIDGTHIAKTLASLNPESCLFIIASKTFTTQETITNAETAKEWLL-----LSAKDP 232

Query: 290 GSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENFVEL 349
            +VAKHFVALSTN  KVKEFGID +NMF+FWDWVGGRYS+WSAIGL I + +G++NF +L
Sbjct: 233 SAVAKHFVALSTNTTKVKEFGIDPKNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQL 292

Query: 350 LTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQQLD 409
           L+GAH +D+HF   P E+N P+LLAL+G+WYIN FG  T A+LPYDQYL R  AY QQ D
Sbjct: 293 LSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETQAMLPYDQYLHRFAAYFQQGD 352

Query: 410 MESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQNKI 469
           MESNGKY+T+SG  V   TGPI++GE GTNGQHAFYQLIHQGT +IPCDF+  +Q+Q+ I
Sbjct: 353 MESNGKYITKSGIRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPI 412

Query: 470 --GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGRPSN 527
             G HHKI ++NF AQTEALM GKS  E R+EL+AAG +S E I  LLPHK F G RP+N
Sbjct: 413 RKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAG-KSPEDIEKLLPHKVFEGNRPTN 471

Query: 528 TLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPGMRV 587
           +++   LTP  LG++IAMYEHK+ VQG IW I+S+DQWGVELGK LAK I P+L     V
Sbjct: 472 SIVFTKLTPFILGSLIAMYEHKIFVQGVIWDINSFDQWGVELGKQLAKKIEPELDGSSAV 531

Query: 588 NNHDSSTNGLINMFNELSH 606
            +HDSSTNGLIN   +   
Sbjct: 532 TSHDSSTNGLINFIKKERE 550
>ref|NP_001085765.1| MGC80718 protein [Xenopus laevis]
 gb|AAH73315.1| MGC80718 protein [Xenopus laevis]
          Length = 553

 Score = 1095 bits (2832), Expect = 0.0,   Method: Composition-based stats.
 Identities = 318/562 (56%), Positives = 409/562 (72%), Gaps = 12/562 (2%)

Query: 48  TTLTSCASWTQLQKLYEQY-GDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
             LT    + +L + YE +     +++ FEAD +R  +YS  +     D+  + LDYSK+
Sbjct: 1   MALTCDPVYQKLSQWYEAHHAGLNMRQMFEADKDRFSKYSKTL---VTDDGDILLDYSKN 57

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            IN+++   L+ LA  RG+    Q +F  E++N TENR VLHIALRNRSN PI +DGKDV
Sbjct: 58  LINEDVLKLLIELARSRGVESARQKMFSAEKINFTENRAVLHIALRNRSNTPIPLDGKDV 117

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN VL++M++F +KVR+G+WKG+ GKAI  VVNIGIGGSDLGP+M TE+LKP+S+  
Sbjct: 118 MPEVNAVLEKMKAFCQKVRSGDWKGYNGKAITDVVNIGIGGSDLGPLMVTESLKPYSKGG 177

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
             + FVSN+DGTHIA+ L  ++ E TLFI+ASKTFTTQETITNA +AR   L+       
Sbjct: 178 PRVWFVSNIDGTHIAKTLAELNPETTLFIIASKTFTTQETITNAETAREWFLN-----SA 232

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            +  +VAKHFVALSTN  KVK+FGID  NMF+FWDWVGGRYS+WSAIGL I + +G++NF
Sbjct: 233 KDASAVAKHFVALSTNAPKVKDFGIDTANMFEFWDWVGGRYSLWSAIGLSIALHVGFDNF 292

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
            +LL GAH +D HF   P E NVP++LA++G+WYINF+G  THA+LPYDQY+ R  AY Q
Sbjct: 293 EKLLAGAHWMDNHFYKTPLENNVPVILAMLGIWYINFYGCETHALLPYDQYMHRFAAYFQ 352

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q DMESNGKY+T++G  V+  TGP+++GE GTNGQHAFYQLIHQGT  IPCDF+  +Q+Q
Sbjct: 353 QGDMESNGKYITKTGARVNYNTGPVVWGEPGTNGQHAFYQLIHQGTRKIPCDFLIPVQTQ 412

Query: 467 NKI--GDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           N I  G HHKI +SNF AQTEALM GKS  E ++EL+A+G  + E ++ LLPHK F G R
Sbjct: 413 NPIRNGLHHKILLSNFLAQTEALMKGKSTDEAKKELQASG-LTGEALDKLLPHKVFEGNR 471

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N+++   L P  LGA+IAMYEHK+ VQG +W I+SYDQWGVELGK LAK I P+L   
Sbjct: 472 PTNSIVFTKLNPFILGALIAMYEHKIFVQGVVWDINSYDQWGVELGKQLAKKIEPELESD 531

Query: 585 MRVNNHDSSTNGLINMFNELSH 606
             + +HD STNGLIN   +   
Sbjct: 532 ATITSHDGSTNGLINFIKKHRS 553
>gb|AAH44450.1| Glucose phosphate isomerase a [Danio rerio]
          Length = 553

 Score = 1093 bits (2828), Expect = 0.0,   Method: Composition-based stats.
 Identities = 324/562 (57%), Positives = 419/562 (74%), Gaps = 12/562 (2%)

Query: 48  TTLTSCASWTQLQKLYEQ-YGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYSKS 106
             L +  ++ +L++ Y+   G+  +++ FEAD++R  ++S+++   S D+  L LD+SK+
Sbjct: 1   MGLNNDPNFIKLEQWYKSSAGNLNMRQMFEADADRFNKFSLQL---STDDGDLLLDFSKN 57

Query: 107 HINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGKDV 166
            IN+++   L  +A   G+    + +F GE++N TE R VLH ALRNRSN PI VDGKDV
Sbjct: 58  LINEDVMSLLFDMARSVGVEAAREQMFAGEKINFTEGRAVLHTALRNRSNTPIMVDGKDV 117

Query: 167 MPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQRD 226
           MP VN+VL+QM+SF  KVR+  WKG +GK+I  VVNIGIGGSDLGP+M TEALKP+S+  
Sbjct: 118 MPEVNRVLEQMKSFCHKVRSSAWKGFSGKSITDVVNIGIGGSDLGPLMVTEALKPYSKGG 177

Query: 227 LSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSRGI 286
            ++ FVSN+DGTH+A+ L  ++ E TLFI+ASKTFTTQETITNA +AR   L     +  
Sbjct: 178 PNVWFVSNIDGTHMAKTLAQLNAETTLFIIASKTFTTQETITNAETAREWFL-----QAA 232

Query: 287 DEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYENF 346
            +K +VAKHFVALSTN  KVKEFGID  NMF+FWDWVGGRYS+WSAIGL I + IG++NF
Sbjct: 233 KDKSAVAKHFVALSTNAPKVKEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALHIGFDNF 292

Query: 347 VELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAYLQ 406
            +LL+GAH +D HF +AP EQN P++LAL+GVWY+NFF A THA+LPYDQY+ R  AY Q
Sbjct: 293 EQLLSGAHWMDNHFRSAPLEQNAPVILALLGVWYVNFFQAETHALLPYDQYMHRFAAYFQ 352

Query: 407 QLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQSQ 466
           Q DMESNGKY+T+SG  V+  TGPI++GE GTNGQHAFYQLIHQGT LIP DF+   QSQ
Sbjct: 353 QGDMESNGKYITKSGTRVNYHTGPIVWGEPGTNGQHAFYQLIHQGTRLIPADFLIPAQSQ 412

Query: 467 NKIGD--HHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           + I D  HHKI M+NF AQTEALM GK+  E ++EL+A+G  S + +  LLPHK F G +
Sbjct: 413 HPIRDNLHHKILMANFLAQTEALMRGKTSDEAKKELQASG-LSGDSLEKLLPHKVFQGNK 471

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           PSN+++ K LTP  LGA++AMYEHK+ VQG +W I+SYDQWGVELGK LAK I P+L+  
Sbjct: 472 PSNSIIFKKLTPFMLGALVAMYEHKIFVQGVMWNINSYDQWGVELGKQLAKKIEPELQDD 531

Query: 585 MRVNNHDSSTNGLINMFNELSH 606
             V++HDSSTNGLI  F +   
Sbjct: 532 AEVHSHDSSTNGLIGFFKKNRS 553
>ref|YP_001480699.1| Glucose-6-phosphate isomerase [Serratia proteamaculans 568]
 sp|A8GKD1|G6PI_SERP5 Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 gb|ABV43571.1| Glucose-6-phosphate isomerase [Serratia proteamaculans 568]
          Length = 548

 Score = 1092 bits (2825), Expect = 0.0,   Method: Composition-based stats.
 Identities = 315/561 (56%), Positives = 400/561 (71%), Gaps = 13/561 (2%)

Query: 45  DADTTLTSCASWTQLQKLYEQYGDEPIKKHFEADSERGQRYSVKVSLGSKDENFLFLDYS 104
             +   +  A+W  LQ+ +EQ  D  I   F  D ER  ++S   +      + + +DYS
Sbjct: 1   MKNINPSQTAAWQALQQHFEQMKDVQISDLFAQDKERFSKFSATFN------DQMLVDYS 54

Query: 105 KSHINDEIKCALLRLAEERGIRQFVQSVFRGERVNTTENRPVLHIALRNRSNRPIYVDGK 164
           K+ I+ E    L  LA+E  ++  ++S+F GE++N TE+R VLH+ALRNRSN PI VDGK
Sbjct: 55  KNRISAETLEKLQALAKETDLQSAIKSMFAGEKINRTEDRAVLHVALRNRSNTPIIVDGK 114

Query: 165 DVMPAVNKVLDQMRSFSEKVRTGEWKGHTGKAIRHVVNIGIGGSDLGPVMATEALKPFSQ 224
           DVMP VN VL +M+ F ++V  G+WKG+TGKAI  VVNIGIGGSDLGP MATEAL+P+ +
Sbjct: 115 DVMPEVNAVLAKMKQFCDRVIGGDWKGYTGKAITDVVNIGIGGSDLGPYMATEALRPY-K 173

Query: 225 RDLSLHFVSNVDGTHIAEVLKSIDIEATLFIVASKTFTTQETITNALSARRALLDYLRSR 284
             L++HFVSNVDGTHIAE L+ ++ E TLF+VASKTFTTQET+TNA SAR   L      
Sbjct: 174 NHLNMHFVSNVDGTHIAETLQPLNPETTLFLVASKTFTTQETMTNAHSARDWFLS----- 228

Query: 285 GIDEKGSVAKHFVALSTNNQKVKEFGIDEENMFQFWDWVGGRYSMWSAIGLPIMISIGYE 344
              ++  VAKHF ALSTN + V  FGID  NMF+FWDWVGGRYS+WSAIGL I +S+G++
Sbjct: 229 TAGDQKHVAKHFAALSTNGKAVGGFGIDTANMFEFWDWVGGRYSLWSAIGLSIALSLGFD 288

Query: 345 NFVELLTGAHVIDEHFANAPPEQNVPLLLALVGVWYINFFGAVTHAILPYDQYLWRLPAY 404
           NF +LL+GAH +D+HFA  P E+N+P+LLAL+G+WY NFFGA T AILPYDQY+ R  AY
Sbjct: 289 NFEQLLSGAHAMDQHFAQTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAY 348

Query: 405 LQQLDMESNGKYVTRSGKTVSTLTGPIIFGEAGTNGQHAFYQLIHQGTNLIPCDFIGAIQ 464
            QQ +MESNGKYV R+G  V   TGPII+GE GTNGQHAFYQLIHQGT L+PCDFI    
Sbjct: 349 FQQGNMESNGKYVDRNGNPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLVPCDFIAPAI 408

Query: 465 SQNKIGDHHKIFMSNFFAQTEALMIGKSPSEVRRELEAAGERSAEKINALLPHKTFIGGR 524
           S N + DHH   +SNFFAQTEAL  GKS   V  E  A G ++ E++  + P K F G R
Sbjct: 409 SHNPLSDHHAKLLSNFFAQTEALAFGKSLEVVEAEFAAQG-KTPEEVKHVAPFKVFEGNR 467

Query: 525 PSNTLLIKSLTPRALGAIIAMYEHKVLVQGAIWGIDSYDQWGVELGKVLAKSILPQLRPG 584
           P+N++L++ +TP +LG++IA+YEHK+  QGAI  I ++DQWGVELGK LA  ILP+L   
Sbjct: 468 PTNSILLREITPFSLGSLIALYEHKIFTQGAILNIFTFDQWGVELGKQLANRILPELAGD 527

Query: 585 MRVNNHDSSTNGLINMFNELS 605
             V++HDSSTN LIN F E  
Sbjct: 528 EAVSSHDSSTNALINRFKEWR 548
  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF excluding environmental samples
  from WGS projects
    Posted date:  May 23, 2008  5:56 PM
  Number of letters in database: 883,778,997
  Number of sequences in database:  2,617,685
  
  Database: /host/Blast/data/nr_perl/nr.01
    Posted date:  May 23, 2008  5:54 PM
  Number of letters in database: 976,759,346
  Number of sequences in database:  2,761,413
  
  Database: /host/Blast/data/nr_perl/nr.02
    Posted date:  May 23, 2008  5:48 PM
  Number of letters in database: 374,670,760
  Number of sequences in database:  1,165,270
  
  Database: /host/Blast/data/nr_perl/nr.03
    Posted date:  Apr 28, 2009  5:40 PM
  Number of letters in database: 114,943,120
  Number of sequences in database:  354,819
  
Lambda     K      H
   0.314    0.188    0.705 

Lambda     K      H
   0.267   0.0577    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,460,999,016
Number of Sequences: 6899187
Number of extensions: 936242789
Number of successful extensions: 1650266
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 5325
Number of HSP's successfully gapped in prelim test: 838
Number of HSP's that attempted gapping in prelim test: 1623927
Number of HSP's gapped (non-prelim): 7666
length of query: 607
length of database: 2,350,152,223
effective HSP length: 140
effective length of query: 467
effective length of database: 1,384,266,043
effective search space: 646452242081
effective search space used: 646452242081
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 83 (36.1 bits)