BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= EAN77090__[Trypanosoma_brucei]
         (241 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           6,899,187 sequences; 2,350,152,223 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_827420.1|  Gim5B protein [Trypanosoma brucei TREU927]...   468   e-130
emb|CAB94857.1|  GIM5B protein [Trypanosoma brucei brucei]        465   e-129
emb|CAB94856.1|  GIM5A protein [Trypanosoma brucei brucei]        413   e-114
ref|XP_827419.1|  Gim5A protein [Trypanosoma brucei TREU927]...   410   e-113
ref|XP_821649.1|  Gim5A protein, putative [Trypanosoma cruzi...   290   8e-77
ref|XP_804598.1|  Gim5A protein, putative [Trypanosoma cruzi...   289   1e-76
ref|XP_811903.1|  Gim5A protein, putative [Trypanosoma cruzi...   258   2e-67
ref|XP_843475.1|  glycosomal membrane protein [Leishmania ma...   227   7e-58
ref|XP_001469178.1|  Gim5A protein; glycosomal membrane prot...   223   1e-56
ref|XP_001568471.1|  Gim5A protein, putative [Leishmania bra...   222   2e-56
ref|XP_804602.1|  Gim5A protein, putative [Trypanosoma cruzi...   178   2e-43
ref|XP_001568470.1|  hypothetical protein LbrM34_V2.3670 [Le...    62   4e-08
ref|XP_804601.1|  hypothetical protein Tc00.1047053510669.9 ...    61   5e-08
ref|XP_811904.1|  hypothetical protein Tc00.1047053507009.20...    58   7e-07
ref|XP_843474.1|  hypothetical protein, conserved [Leishmani...    46   0.003
ref|XP_001469177.1|  hypothetical protein [Leishmania infant...    45   0.006
ref|ZP_01386365.1|  hypothetical protein CferDRAFT_0813 [Chl...    37   1.3  
ref|ZP_03921912.1|  ABC superfamily ATP binding cassette tra...    36   1.8  
ref|ZP_01039379.1|  sulfate permease [Erythrobacter sp. NAP1...    36   2.7  
ref|ZP_01037126.1|  sulfate permease [Roseovarius sp. 217] >...    35   5.4  
>ref|XP_827420.1| Gim5B protein [Trypanosoma brucei TREU927]
 gb|EAN77090.1| Gim5B protein [Trypanosoma brucei]
          Length = 241

 Score =  468 bits (1203), Expect = e-130,   Method: Composition-based stats.
 Identities = 241/241 (100%), Positives = 241/241 (100%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
           VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF
Sbjct: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240

Query: 241 Y 241
           Y
Sbjct: 241 Y 241
>emb|CAB94857.1| GIM5B protein [Trypanosoma brucei brucei]
          Length = 241

 Score =  465 bits (1197), Expect = e-129,   Method: Composition-based stats.
 Identities = 240/241 (99%), Positives = 240/241 (99%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKP GDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPAGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
           VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF
Sbjct: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240

Query: 241 Y 241
           Y
Sbjct: 241 Y 241
>emb|CAB94856.1| GIM5A protein [Trypanosoma brucei brucei]
          Length = 243

 Score =  413 bits (1061), Expect = e-114,   Method: Composition-based stats.
 Identities = 218/243 (89%), Positives = 224/243 (92%), Gaps = 2/243 (0%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRG-HCTAAAASGDDKR-KTCPYGGCKRVMVDLL 178
           LSGVAVLCWMYTLVLGIVRQLY+  K+R    +  A +GDDK+     Y   KR  V+LL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYLFVKLRPRQASRGAGAGDDKKVPAYTYLELKRAFVNLL 180

Query: 179 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 238
           KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC
Sbjct: 181 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 240

Query: 239 EFY 241
           EFY
Sbjct: 241 EFY 243
>ref|XP_827419.1| Gim5A protein [Trypanosoma brucei TREU927]
 gb|EAN77089.1| Gim5A protein [Trypanosoma brucei]
          Length = 243

 Score =  410 bits (1053), Expect = e-113,   Method: Composition-based stats.
 Identities = 216/243 (88%), Positives = 222/243 (91%), Gaps = 2/243 (0%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRG-HCTAAAASGDDKR-KTCPYGGCKRVMVDLL 178
           LSGVAVLCWMYTL LGIVRQLY+  K+R    +  A +GDDK+     Y   KR  V+LL
Sbjct: 121 LSGVAVLCWMYTLALGIVRQLYLFVKLRPRQASRGAGAGDDKKVPAYTYLELKRAFVNLL 180

Query: 179 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 238
           KLVCYFLFALTCLPEGKPQLLANA GPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC
Sbjct: 181 KLVCYFLFALTCLPEGKPQLLANARGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 240

Query: 239 EFY 241
           EFY
Sbjct: 241 EFY 243
>ref|XP_821649.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN99798.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 244

 Score =  290 bits (741), Expect = 8e-77,   Method: Composition-based stats.
 Identities = 154/245 (62%), Positives = 189/245 (77%), Gaps = 5/245 (2%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA AHTYL D WNRDKVMAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTR
Sbjct: 1   MSACAHTYLSDTWNRDKVMAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLL NALS  TL  L+KP GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R
Sbjct: 61  LSLLLNALSSKTLKDLTKPKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVD 176
             GVAV+CW+YTL+LGI RQ Y+L+K   RG C A     D ++K  PY    CKR +V+
Sbjct: 121 FGGVAVVCWLYTLLLGIARQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVN 179

Query: 177 LLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIAS 236
           L+K+ C+ +FA+TCLPEG+P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS
Sbjct: 180 LVKMSCFAVFAMTCLPEGRPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATAS 239

Query: 237 VCEFY 241
           +C+FY
Sbjct: 240 LCDFY 244
>ref|XP_804598.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN82747.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 244

 Score =  289 bits (739), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 154/245 (62%), Positives = 189/245 (77%), Gaps = 5/245 (2%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA AHTYL D WNRDKVMAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTR
Sbjct: 1   MSACAHTYLSDTWNRDKVMAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLL NALS  TL  L+KP GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R
Sbjct: 61  LSLLLNALSSKTLKDLAKPKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVD 176
             GVAV+CW+YTL+LGI RQ Y+L+K   RG C A     D ++K  PY    CKR +V+
Sbjct: 121 FGGVAVVCWLYTLLLGIARQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVN 179

Query: 177 LLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIAS 236
           L+K+ C+ +FA+TCLPEG+P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS
Sbjct: 180 LVKMSCFAVFAMTCLPEGRPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATAS 239

Query: 237 VCEFY 241
           +C+FY
Sbjct: 240 LCDFY 244
>ref|XP_811903.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN90052.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 226

 Score =  258 bits (659), Expect = 2e-67,   Method: Composition-based stats.
 Identities = 139/227 (61%), Positives = 174/227 (76%), Gaps = 5/227 (2%)

Query: 19  MAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSLSK 78
           MAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTRLSLL NALS  TL  L+K
Sbjct: 1   MAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTRLSLLLNALSSKTLKDLTK 60

Query: 79  PTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLVLGIV 138
           P GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R  GVAV+CW+YTL+LGI 
Sbjct: 61  PKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTRFGGVAVVCWLYTLLLGIA 120

Query: 139 RQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVDLLKLVCYFLFALTCLPEG 194
           RQ Y+L+K   RG C A     D ++K  PY    CKR +V+L+K+ C+ +FA+TCLPEG
Sbjct: 121 RQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVNLVKMSCFAVFAMTCLPEG 179

Query: 195 KPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEFY 241
           +P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS+C+FY
Sbjct: 180 RPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATASLCDFY 226
>ref|XP_843475.1| glycosomal membrane protein [Leishmania major strain Friedlin]
 gb|AAZ14593.1| glycosomal membrane protein [Leishmania major strain Friedlin]
          Length = 225

 Score =  227 bits (578), Expect = 7e-58,   Method: Composition-based stats.
 Identities = 129/241 (53%), Positives = 166/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSAAVFEYLGNTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSSMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P    R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDVLLDRVDQLSHFFHVCFCFFENTAVLSSHNVYPNRFVR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++               K+K  P    KR MV  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMT---------------KKKNTPEEQ-KRQMVTTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPLVPLH  ++ ++P  L  ++T+RG+LG IAS+C+F
Sbjct: 165 GCFLIFSLTCFPKGGPQLLEDVSGPLVPLHKTLQLIAPKHLELNDTIRGVLGFIASMCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>ref|XP_001469178.1| Gim5A protein; glycosomal membrane protein [Leishmania infantum]
 emb|CAM72280.1| Gim5A protein, putative; glycosomal membrane protein [Leishmania
           infantum]
          Length = 225

 Score =  223 bits (567), Expect = 1e-56,   Method: Composition-based stats.
 Identities = 128/241 (53%), Positives = 165/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSAAVFEYLGNTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSSMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P    R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDVLLDRVDQLSHFFHVCFCFFENTAVLSSHNVYPNRFVR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++               ++K  P    KR MV  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMT---------------QKKNTPEEQ-KRQMVTTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPLVPLH  ++ ++P  L  ++T+RG LG IAS+C+F
Sbjct: 165 GCFLIFSLTCFPKGGPQLLEDVSGPLVPLHKTLQLIAPKHLGLNDTIRGALGFIASMCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>ref|XP_001568471.1| Gim5A protein, putative [Leishmania braziliensis MHOM/BR/75/M2904]
 emb|CAM43585.1| Gim5A protein, putative; glycosomal membrane protein [Leishmania
           braziliensis]
          Length = 225

 Score =  222 bits (565), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 127/241 (52%), Positives = 166/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSASVFQYLANTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSTMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P  L R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDILLDRLDQLSHFFHVCFCFFENTAVLSSHNVYPSRLGR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++               ++K  P    KR M+  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMT---------------QKKNTPEEH-KRQMITTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPL+PLH  ++ ++P  L  ++T+RG LG IAS+C+F
Sbjct: 165 GCFLVFSLTCFPKGGPQLLEDVSGPLMPLHKTLQLIAPKCLELNDTIRGALGFIASLCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>ref|XP_804602.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN82751.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 161

 Score =  178 bits (452), Expect = 2e-43,   Method: Composition-based stats.
 Identities = 90/159 (56%), Positives = 118/159 (74%), Gaps = 5/159 (3%)

Query: 87  RIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLVLGIVRQLYMLSK 146
           R++Q+SH FHIGFCLNE+TAVLAG GV    L R  GVAV+CW+YTL+LGI RQ Y+L+K
Sbjct: 4   RLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTRFGGVAVVCWLYTLLLGIARQAYLLAK 63

Query: 147 M--RGHCTAAAASGDDKRKTCPYGG--CKRVMVDLLKLVCYFLFALTCLPEGKPQLLANA 202
              RG C A     D ++K  PY    CKR +V+L+K+ C+ +FA TCLPEG+P+LL + 
Sbjct: 64  HSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVNLVKMSCFAVFAKTCLPEGRPKLLQDV 122

Query: 203 SGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEFY 241
            GPLVPLH +++A++PN LH S+TVRGLL   AS+C+FY
Sbjct: 123 CGPLVPLHELIRAIAPNKLHLSDTVRGLLAATASLCDFY 161
>ref|XP_001568470.1| hypothetical protein LbrM34_V2.3670 [Leishmania braziliensis
           MHOM/BR/75/M2904]
 emb|CAM43584.1| hypothetical protein, conserved [Leishmania braziliensis]
          Length = 253

 Score = 61.6 bits (148), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 72/250 (28%), Positives = 111/250 (44%), Gaps = 24/250 (9%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS 62
           A  + Y+ +  NRD+VM++VQF  MAL GPA  AGC  L+     +  +   YR +TR S
Sbjct: 11  ATFNDYIGNVSNRDRVMSVVQFSAMALTGPAAAAGCSKLSAHFNTIHHIAAHYRTITRFS 70

Query: 63  ---LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHG-----VF 114
              ++A AL+   +T       + +      +S  F   F + E   VLA        V 
Sbjct: 71  QWLVVAPALTYSGITGALNSHPNPLVGICKTISTAFFTVFLIGEEL-VLASKSNMLDPVL 129

Query: 115 PKSLHRLSGVAVLCWMYTLVLGIVRQL--YMLSKMRGHCTAAAASGDDKRKTCPYGGCKR 172
            K L+R+  V  L W       I R +  Y+L K   +        + K K         
Sbjct: 130 GKHLNRIRFV-FLFWS-----NIARLIMNYLLLKSSSYDAVKDTQNEKKAKDHRRKVLSV 183

Query: 173 VMVDLLKLVCYFLFALTCLPEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGL 230
               L  + CY L   +  P G P+ L+ A  SG +V +   + +L+P  +   +T +G+
Sbjct: 184 ADGVLQSMFCYTLLK-SSAPAG-PKYLSAALQSGNVVDV---ITSLAPPLIAVPSTPQGI 238

Query: 231 LGLIASVCEF 240
           +GL+ASV  F
Sbjct: 239 IGLVASVPGF 248
>ref|XP_804601.1| hypothetical protein Tc00.1047053510669.9 [Trypanosoma cruzi strain
           CL Brener]
 gb|EAN82750.1| hypothetical protein, conserved [Trypanosoma cruzi]
          Length = 247

 Score = 61.2 bits (147), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 61/243 (25%), Positives = 107/243 (44%), Gaps = 16/243 (6%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS 62
           A  H+YL  AW RD+V A++QF  M + G A + G  S+  S  +LAR+   Y +VTR+ 
Sbjct: 4   ALPHSYLSIAWRRDRVTAVLQFCSMVVSGVAGSVGQRSIERSAKSLARLLSEYGSVTRVC 63

Query: 63  -----LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKS 117
                LL  + +    T  + P      +RI  ++ +F   F  +E   +LA  GV  K 
Sbjct: 64  NWLVVLLELSPAGVRRTMRASPGFFTGIARI--VTTIFLGLFLASEEVELLAAGGVLSKV 121

Query: 118 L--HRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMV 175
              H    V +  + Y L+        + +  R      +    D +        K + +
Sbjct: 122 WRPHAARMVPIFFFYYNLLKAGTSAALLQAMQR-----ISFEATDTQSVIRKRHYKELFL 176

Query: 176 DLLKLVCYFLFALTCLPEGKPQL--LANASGPLVPLHVMVKALSPNPLHASNTVRGLLGL 233
             ++ + + ++A+T LP   P+L    N    +  ++ +  +L P  +      +GLLGL
Sbjct: 177 SFMEGIAFMVYAMTLLPSNAPRLREALNEGLWMDRVYSVFSSLCPQAVQVRPATQGLLGL 236

Query: 234 IAS 236
           +A+
Sbjct: 237 LAT 239
>ref|XP_811904.1| hypothetical protein Tc00.1047053507009.20 [Trypanosoma cruzi
           strain CL Brener]
 gb|EAN90053.1| hypothetical protein, conserved [Trypanosoma cruzi]
          Length = 247

 Score = 57.8 bits (138), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 62/246 (25%), Positives = 106/246 (43%), Gaps = 22/246 (8%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR-- 60
           A  H+ L  AW RD+V A++QF  M + G A + G  S+  S  +LAR+   Y +VTR  
Sbjct: 4   ALPHSCLSIAWRRDRVPAVLQFCSMVVSGVAGSVGHRSIERSAKSLARLLSEYGSVTRVC 63

Query: 61  ------LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVF 114
                 L L    + +   TS    TG    +RI  ++ +F   F  +E   +LA  GV 
Sbjct: 64  NWLVVLLELSPAGVRRTMRTSPGFFTG---IARI--VTTIFLGLFLASEEVELLAAGGVL 118

Query: 115 PK--SLHRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKR 172
            K    H    V +  + Y L+        + +  R      +    D +        K 
Sbjct: 119 SKLWRPHAARMVPIFFFYYNLLKAATSAALLQAMQR-----ISFEATDTQSVIRKRHYKE 173

Query: 173 VMVDLLKLVCYFLFALTCLPEGKPQL--LANASGPLVPLHVMVKALSPNPLHASNTVRGL 230
           + +  ++ + + ++A+T LP   P+L    N    +  ++ +  +L P  +      +GL
Sbjct: 174 LFLSFMEGIAFMVYAMTLLPSNAPRLREALNEGFWMDRVYSVFSSLCPQAVQVRPATQGL 233

Query: 231 LGLIAS 236
           LGL+A+
Sbjct: 234 LGLLAT 239
>ref|XP_843474.1| hypothetical protein, conserved [Leishmania major strain Friedlin]
 gb|AAZ14592.1| hypothetical protein, conserved [Leishmania major strain Friedlin]
          Length = 253

 Score = 45.8 bits (107), Expect = 0.003,   Method: Composition-based stats.
 Identities = 64/240 (26%), Positives = 105/240 (43%), Gaps = 10/240 (4%)

Query: 6   HTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS--- 62
           + Y+ +A NRD+VM++VQF  MAL  PA  AGC  L+  L  +      YR VTR S   
Sbjct: 14  NNYVGNASNRDRVMSVVQFGAMALAAPAAAAGCPELSAHLSTILHGAAHYRTVTRFSQWL 73

Query: 63  LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLS 122
           ++A AL+   + S      +++      +S  F   F + E   + +   +    L +  
Sbjct: 74  VVAPALTPSGIKSAIASHPNLLVGICKTISTAFFTVFLIGEELVLASKCNMLDPVLGKRF 133

Query: 123 GVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKLVC 182
                 +++   +  +   Y+L K   +        ++K K             L  + C
Sbjct: 134 NRIRFVFLFWSNIARLVMSYLLLKSSKYDAVKDNQNEEKAKDHRRKVLGVADGVLQSMFC 193

Query: 183 YFLFALTCLPEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
           Y L   +  P G P+ L+ A  SG  V +   + +L+P  L   +T +G+LGL ASV  F
Sbjct: 194 YTLLK-SSAPAG-PKYLSAALRSGKAVDI---ITSLAPPLLVVPSTPQGMLGLAASVPGF 248
>ref|XP_001469177.1| hypothetical protein [Leishmania infantum]
 emb|CAM72279.1| hypothetical protein, conserved [Leishmania infantum]
          Length = 253

 Score = 44.7 bits (104), Expect = 0.006,   Method: Composition-based stats.
 Identities = 73/249 (29%), Positives = 114/249 (45%), Gaps = 32/249 (12%)

Query: 8   YLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS---LL 64
           Y+ +A NRD+VM++VQF  MAL  PA  AGC  L+     +      YR VTR S   ++
Sbjct: 16  YVGNASNRDRVMSVVQFGAMALVAPAAAAGCPELSAHFDTILHGAAHYRTVTRFSQWLVV 75

Query: 65  ANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGH-----GVFPKSLH 119
           A AL+   + S+     + +      +S  F   F + E   VLA        VF +  +
Sbjct: 76  APALTPSGIKSVIASHPNPLVGICKTISTAFFTVFLIGEEL-VLASKCNMLDPVFGRHFN 134

Query: 120 RLSGVAVLCW--MYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDL 177
           R+  V  L W  +  LV+      Y+L K   +     +  ++K K       +R ++++
Sbjct: 135 RIRFV-FLFWSNIARLVMN-----YLLLKSSKYDAVKDSQNEEKAKD-----HRRKVLNV 183

Query: 178 LKLVCYFLFALTCL----PEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGLL 231
              V   +F  T L    P G P+ L+ A  SG  V +   + +L+P      +T +G+L
Sbjct: 184 ADGVLQSMFCYTLLKSSAPAG-PKYLSAALRSGKAVDI---ITSLAPPLFVVPSTPQGML 239

Query: 232 GLIASVCEF 240
           GL ASV  F
Sbjct: 240 GLAASVPGF 248
>ref|ZP_01386365.1| hypothetical protein CferDRAFT_0813 [Chlorobium ferrooxidans DSM
           13031]
 gb|EAT58839.1| hypothetical protein CferDRAFT_0813 [Chlorobium ferrooxidans DSM
           13031]
          Length = 2110

 Score = 37.0 bits (84), Expect = 1.3,   Method: Composition-based stats.
 Identities = 17/41 (41%), Positives = 23/41 (56%)

Query: 191 LPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLL 231
           L    P++ ANA    VPLH +++AL PNP    N +  LL
Sbjct: 491 LSSQNPRVQANALSIKVPLHEILRALGPNPTTVDNAISNLL 531
>ref|ZP_03921912.1| ABC superfamily ATP binding cassette transporter ABC protein
           [Corynebacterium pseudogenitalium ATCC 33035]
 gb|EEJ37635.1| ABC superfamily ATP binding cassette transporter ABC protein
           [Corynebacterium pseudogenitalium ATCC 33035]
          Length = 581

 Score = 36.2 bits (82), Expect = 1.8,   Method: Composition-based stats.
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 9/100 (9%)

Query: 48  LARMGDAYRAVTRLSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAV 107
           L+R+ +   +  R  +++ AL  PT       TGD+V+   D ++ L      + E   V
Sbjct: 89  LSRLSERVISALREDMVSTALRLPTHRVEEAGTGDLVSRSTDDVAEL---SAAVTETVPV 145

Query: 108 LAGHGVFPKSLHRLSGVAV--LCWMYTLVLGIVRQLYMLS 145
           LA   VF  +    +GVA+  L W Y LV+G V  LY ++
Sbjct: 146 LA-KSVFAIAT---TGVALVSLNWQYLLVVGAVTPLYFIA 181
>ref|ZP_01039379.1| sulfate permease [Erythrobacter sp. NAP1]
 gb|EAQ29850.1| sulfate permease [Erythrobacter sp. NAP1]
          Length = 588

 Score = 35.8 bits (81), Expect = 2.7,   Method: Composition-based stats.
 Identities = 36/147 (24%), Positives = 61/147 (41%), Gaps = 15/147 (10%)

Query: 19  MAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVT---RLSLLANALSKPTLTS 75
           +A++  +  +  G     G      +   LA +  A  A+    R   LAN LS P ++ 
Sbjct: 80  VAVISLMTASAAGSVAAQGTAEYLEAAITLAMLSGAMLAILGLLRAGFLANLLSHPVISG 139

Query: 76  LSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLVL 135
               +G ++A+   Q+ H+            V AG   +P  L  L+       ++TLV+
Sbjct: 140 FITASGILIAT--SQIKHIL----------GVDAGGDTWPAMLGSLAVAVGDTNVWTLVI 187

Query: 136 GIVRQLYMLSKMRGHCTAAAASGDDKR 162
           GI   L++    +G  +A  A G  KR
Sbjct: 188 GIPATLFLFWVRKGGSSALQAIGLRKR 214
>ref|ZP_01037126.1| sulfate permease [Roseovarius sp. 217]
 gb|EAQ24483.1| sulfate permease [Roseovarius sp. 217]
          Length = 584

 Score = 34.7 bits (78), Expect = 5.4,   Method: Composition-based stats.
 Identities = 37/125 (29%), Positives = 56/125 (44%), Gaps = 8/125 (6%)

Query: 19  MAIVQFLPMALEG---PARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTS 75
           +A+V  +  A  G    A TAG    AL+L  L+ +      + RL  LAN LS P +  
Sbjct: 81  VAVVSLMTAAAIGDVAEAGTAGYAVAALTLAGLSGLILLTMGILRLGFLANFLSHPVIAG 140

Query: 76  LSKPTGDMVASRIDQLSHLFHI---GFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYT 132
               +G ++A  + QL HL  +   G  L +    L  H     SL  L GVA   +++ 
Sbjct: 141 FITASGILIA--VSQLKHLLGVKASGGSLPDMLWSLLWHLADINSLTLLIGVASAAFLFW 198

Query: 133 LVLGI 137
           +  G+
Sbjct: 199 VRRGL 203
Searching..................................................done Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|XP_827420.1|  Gim5B protein [Trypanosoma brucei TREU927]...   401   e-110
emb|CAB94857.1|  GIM5B protein [Trypanosoma brucei brucei]        400   e-110
emb|CAB94856.1|  GIM5A protein [Trypanosoma brucei brucei]        380   e-104
ref|XP_827419.1|  Gim5A protein [Trypanosoma brucei TREU927]...   377   e-103
ref|XP_821649.1|  Gim5A protein, putative [Trypanosoma cruzi...   374   e-102
ref|XP_804598.1|  Gim5A protein, putative [Trypanosoma cruzi...   373   e-102
ref|XP_811903.1|  Gim5A protein, putative [Trypanosoma cruzi...   336   8e-91
ref|XP_843475.1|  glycosomal membrane protein [Leishmania ma...   314   5e-84
ref|XP_001568471.1|  Gim5A protein, putative [Leishmania bra...   312   2e-83
ref|XP_001469178.1|  Gim5A protein; glycosomal membrane prot...   309   8e-83
ref|XP_804601.1|  hypothetical protein Tc00.1047053510669.9 ...   282   2e-74
ref|XP_811904.1|  hypothetical protein Tc00.1047053507009.20...   281   3e-74
ref|XP_001568470.1|  hypothetical protein LbrM34_V2.3670 [Le...   263   1e-68
ref|XP_804602.1|  Gim5A protein, putative [Trypanosoma cruzi...   239   2e-61
Sequences not found previously or not previously below threshold:

ref|XP_001469177.1|  hypothetical protein [Leishmania infant...   204   4e-51
ref|XP_843474.1|  hypothetical protein, conserved [Leishmani...   202   2e-50
ref|XP_827421.1|  hypothetical protein Tb09.211.2750 [Trypan...   107   7e-22
gb|ACO51908.1|  Peroxisomal membrane protein 11C [Rana cates...    41   0.067
ref|NP_001090009.1|  hypothetical protein LOC735081 [Xenopus...    39   0.25 
ref|NP_611071.1|  CG8315 CG8315-PA [Drosophila melanogaster]...    38   0.49 
ref|XP_001321770.1|  conserved hypothetical protein [Trichom...    37   1.1  
gb|EEH53081.1|  predicted protein [Micromonas pusilla CCMP1545]    37   1.5  
ref|XP_001838198.1|  hypothetical protein CC1G_07939 [Coprin...    37   1.6  
gb|EDN36632.1|  predicted protein [Francisella tularensis su...    37   1.6  
ref|NP_651137.3|  CG13827 CG13827-PA [Drosophila melanogaste...    36   1.9  
ref|ZP_01390434.1|  DNA polymerase III, alpha subunit [Geoba...    36   1.9  
ref|NP_001006340.1|  peroxisomal biogenesis factor 11 gamma ...    36   2.1  
ref|XP_001239782.1|  hypothetical protein CIMG_09403 [Coccid...    36   2.3  
ref|YP_702234.1|  D-serine/D-alanine/glycine transporter, AP...    36   2.7  
ref|XP_394365.2|  PREDICTED: similar to CG8315-PA isoform 1 ...    36   3.3  
ref|XP_001358348.1|  GA12553-PA [Drosophila pseudoobscura] >...    36   3.4  
ref|XP_954194.1|  DEAD-box helicase, putative [Theileria ann...    35   3.8  
ref|NP_784281.1|  fucose transport protein [Lactobacillus pl...    35   4.2  
ref|XP_001215122.1|  predicted protein [Aspergillus terreus ...    35   5.1  
ref|NP_542393.1|  peroxisomal biogenesis factor 11 gamma [Ho...    35   5.6  
gb|AAU08775.1|  cytochrome b [Rhinogobius sp. YB]                  34   6.7  
gb|AAU08771.1|  cytochrome b [Rhinogobius sp. YB] >gi|517023...    34   6.8  
ref|XP_317688.3|  AGAP007812-PA [Anopheles gambiae str. PEST...    34   7.1  
gb|AAU08772.1|  cytochrome b [Rhinogobius sp. YB] >gi|517023...    34   7.2  
gb|ABF19672.1|  cytochrome b [Ctenogobiops feroculus]              34   7.2  
ref|YP_001231258.1|  DNA polymerase III, alpha subunit [Geob...    34   7.3  
gb|AAO34460.1|AF454888_1  cytochrome b [Moxostoma breviceps]       34   8.6  
ref|XP_001497087.1|  PREDICTED: similar to Peroxisomal bioge...    34   9.1  
ref|NP_001072770.1|  hypothetical protein LOC780227 [Xenopus...    34   10.0 
>ref|XP_827420.1| Gim5B protein [Trypanosoma brucei TREU927]
 gb|EAN77090.1| Gim5B protein [Trypanosoma brucei]
          Length = 241

 Score =  401 bits (1032), Expect = e-110,   Method: Composition-based stats.
 Identities = 241/241 (100%), Positives = 241/241 (100%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
           VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF
Sbjct: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240

Query: 241 Y 241
           Y
Sbjct: 241 Y 241
>emb|CAB94857.1| GIM5B protein [Trypanosoma brucei brucei]
          Length = 241

 Score =  400 bits (1028), Expect = e-110,   Method: Composition-based stats.
 Identities = 240/241 (99%), Positives = 240/241 (99%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKP GDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPAGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
           VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF
Sbjct: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240

Query: 241 Y 241
           Y
Sbjct: 241 Y 241
>emb|CAB94856.1| GIM5A protein [Trypanosoma brucei brucei]
          Length = 243

 Score =  380 bits (977), Expect = e-104,   Method: Composition-based stats.
 Identities = 218/243 (89%), Positives = 224/243 (92%), Gaps = 2/243 (0%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRG-HCTAAAASGDDKR-KTCPYGGCKRVMVDLL 178
           LSGVAVLCWMYTLVLGIVRQLY+  K+R    +  A +GDDK+     Y   KR  V+LL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYLFVKLRPRQASRGAGAGDDKKVPAYTYLELKRAFVNLL 180

Query: 179 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 238
           KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC
Sbjct: 181 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 240

Query: 239 EFY 241
           EFY
Sbjct: 241 EFY 243
>ref|XP_827419.1| Gim5A protein [Trypanosoma brucei TREU927]
 gb|EAN77089.1| Gim5A protein [Trypanosoma brucei]
          Length = 243

 Score =  377 bits (968), Expect = e-103,   Method: Composition-based stats.
 Identities = 216/243 (88%), Positives = 222/243 (91%), Gaps = 2/243 (0%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRG-HCTAAAASGDDKR-KTCPYGGCKRVMVDLL 178
           LSGVAVLCWMYTL LGIVRQLY+  K+R    +  A +GDDK+     Y   KR  V+LL
Sbjct: 121 LSGVAVLCWMYTLALGIVRQLYLFVKLRPRQASRGAGAGDDKKVPAYTYLELKRAFVNLL 180

Query: 179 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 238
           KLVCYFLFALTCLPEGKPQLLANA GPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC
Sbjct: 181 KLVCYFLFALTCLPEGKPQLLANARGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 240

Query: 239 EFY 241
           EFY
Sbjct: 241 EFY 243
>ref|XP_821649.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN99798.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 244

 Score =  374 bits (960), Expect = e-102,   Method: Composition-based stats.
 Identities = 154/245 (62%), Positives = 189/245 (77%), Gaps = 5/245 (2%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA AHTYL D WNRDKVMAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTR
Sbjct: 1   MSACAHTYLSDTWNRDKVMAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLL NALS  TL  L+KP GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R
Sbjct: 61  LSLLLNALSSKTLKDLTKPKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVD 176
             GVAV+CW+YTL+LGI RQ Y+L+K   RG C A     D ++K  PY    CKR +V+
Sbjct: 121 FGGVAVVCWLYTLLLGIARQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVN 179

Query: 177 LLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIAS 236
           L+K+ C+ +FA+TCLPEG+P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS
Sbjct: 180 LVKMSCFAVFAMTCLPEGRPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATAS 239

Query: 237 VCEFY 241
           +C+FY
Sbjct: 240 LCDFY 244
>ref|XP_804598.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN82747.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 244

 Score =  373 bits (959), Expect = e-102,   Method: Composition-based stats.
 Identities = 154/245 (62%), Positives = 189/245 (77%), Gaps = 5/245 (2%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA AHTYL D WNRDKVMAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTR
Sbjct: 1   MSACAHTYLSDTWNRDKVMAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLL NALS  TL  L+KP GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R
Sbjct: 61  LSLLLNALSSKTLKDLAKPKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVD 176
             GVAV+CW+YTL+LGI RQ Y+L+K   RG C A     D ++K  PY    CKR +V+
Sbjct: 121 FGGVAVVCWLYTLLLGIARQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVN 179

Query: 177 LLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIAS 236
           L+K+ C+ +FA+TCLPEG+P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS
Sbjct: 180 LVKMSCFAVFAMTCLPEGRPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATAS 239

Query: 237 VCEFY 241
           +C+FY
Sbjct: 240 LCDFY 244
>ref|XP_811903.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN90052.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 226

 Score =  336 bits (862), Expect = 8e-91,   Method: Composition-based stats.
 Identities = 139/227 (61%), Positives = 174/227 (76%), Gaps = 5/227 (2%)

Query: 19  MAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSLSK 78
           MAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTRLSLL NALS  TL  L+K
Sbjct: 1   MAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTRLSLLLNALSSKTLKDLTK 60

Query: 79  PTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLVLGIV 138
           P GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R  GVAV+CW+YTL+LGI 
Sbjct: 61  PKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTRFGGVAVVCWLYTLLLGIA 120

Query: 139 RQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVDLLKLVCYFLFALTCLPEG 194
           RQ Y+L+K   RG C A     D ++K  PY    CKR +V+L+K+ C+ +FA+TCLPEG
Sbjct: 121 RQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVNLVKMSCFAVFAMTCLPEG 179

Query: 195 KPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEFY 241
           +P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS+C+FY
Sbjct: 180 RPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATASLCDFY 226
>ref|XP_843475.1| glycosomal membrane protein [Leishmania major strain Friedlin]
 gb|AAZ14593.1| glycosomal membrane protein [Leishmania major strain Friedlin]
          Length = 225

 Score =  314 bits (804), Expect = 5e-84,   Method: Composition-based stats.
 Identities = 129/241 (53%), Positives = 166/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSAAVFEYLGNTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSSMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P    R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDVLLDRVDQLSHFFHVCFCFFENTAVLSSHNVYPNRFVR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++K               +K  P    KR MV  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMTK---------------KKNTPEEQ-KRQMVTTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPLVPLH  ++ ++P  L  ++T+RG+LG IAS+C+F
Sbjct: 165 GCFLIFSLTCFPKGGPQLLEDVSGPLVPLHKTLQLIAPKHLELNDTIRGVLGFIASMCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>ref|XP_001568471.1| Gim5A protein, putative [Leishmania braziliensis MHOM/BR/75/M2904]
 emb|CAM43585.1| Gim5A protein, putative; glycosomal membrane protein [Leishmania
           braziliensis]
          Length = 225

 Score =  312 bits (799), Expect = 2e-83,   Method: Composition-based stats.
 Identities = 127/241 (52%), Positives = 166/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSASVFQYLANTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSTMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P  L R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDILLDRLDQLSHFFHVCFCFFENTAVLSSHNVYPSRLGR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++               ++K  P    KR M+  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMT---------------QKKNTPEEH-KRQMITTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPL+PLH  ++ ++P  L  ++T+RG LG IAS+C+F
Sbjct: 165 GCFLVFSLTCFPKGGPQLLEDVSGPLMPLHKTLQLIAPKCLELNDTIRGALGFIASLCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>ref|XP_001469178.1| Gim5A protein; glycosomal membrane protein [Leishmania infantum]
 emb|CAM72280.1| Gim5A protein, putative; glycosomal membrane protein [Leishmania
           infantum]
          Length = 225

 Score =  309 bits (793), Expect = 8e-83,   Method: Composition-based stats.
 Identities = 128/241 (53%), Positives = 165/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSAAVFEYLGNTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSSMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P    R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDVLLDRVDQLSHFFHVCFCFFENTAVLSSHNVYPNRFVR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++               ++K  P    KR MV  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMT---------------QKKNTPEEQ-KRQMVTTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPLVPLH  ++ ++P  L  ++T+RG LG IAS+C+F
Sbjct: 165 GCFLIFSLTCFPKGGPQLLEDVSGPLVPLHKTLQLIAPKHLGLNDTIRGALGFIASMCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>ref|XP_804601.1| hypothetical protein Tc00.1047053510669.9 [Trypanosoma cruzi strain
           CL Brener]
 gb|EAN82750.1| hypothetical protein, conserved [Trypanosoma cruzi]
          Length = 247

 Score =  282 bits (721), Expect = 2e-74,   Method: Composition-based stats.
 Identities = 61/245 (24%), Positives = 107/245 (43%), Gaps = 16/245 (6%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS 62
           A  H+YL  AW RD+V A++QF  M + G A + G  S+  S  +LAR+   Y +VTR+ 
Sbjct: 4   ALPHSYLSIAWRRDRVTAVLQFCSMVVSGVAGSVGQRSIERSAKSLARLLSEYGSVTRVC 63

Query: 63  -----LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPK- 116
                LL  + +    T  + P      +RI  ++ +F   F  +E   +LA  GV  K 
Sbjct: 64  NWLVVLLELSPAGVRRTMRASPGFFTGIARI--VTTIFLGLFLASEEVELLAAGGVLSKV 121

Query: 117 -SLHRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMV 175
              H    V +  + Y L+        + +  R      +    D +        K + +
Sbjct: 122 WRPHAARMVPIFFFYYNLLKAGTSAALLQAMQR-----ISFEATDTQSVIRKRHYKELFL 176

Query: 176 DLLKLVCYFLFALTCLPEGKPQL--LANASGPLVPLHVMVKALSPNPLHASNTVRGLLGL 233
             ++ + + ++A+T LP   P+L    N    +  ++ +  +L P  +      +GLLGL
Sbjct: 177 SFMEGIAFMVYAMTLLPSNAPRLREALNEGLWMDRVYSVFSSLCPQAVQVRPATQGLLGL 236

Query: 234 IASVC 238
           +A+  
Sbjct: 237 LATAP 241
>ref|XP_811904.1| hypothetical protein Tc00.1047053507009.20 [Trypanosoma cruzi
           strain CL Brener]
 gb|EAN90053.1| hypothetical protein, conserved [Trypanosoma cruzi]
          Length = 247

 Score =  281 bits (720), Expect = 3e-74,   Method: Composition-based stats.
 Identities = 60/245 (24%), Positives = 106/245 (43%), Gaps = 16/245 (6%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS 62
           A  H+ L  AW RD+V A++QF  M + G A + G  S+  S  +LAR+   Y +VTR+ 
Sbjct: 4   ALPHSCLSIAWRRDRVPAVLQFCSMVVSGVAGSVGHRSIERSAKSLARLLSEYGSVTRVC 63

Query: 63  -----LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPK- 116
                LL  + +    T  + P      +RI  ++ +F   F  +E   +LA  GV  K 
Sbjct: 64  NWLVVLLELSPAGVRRTMRTSPGFFTGIARI--VTTIFLGLFLASEEVELLAAGGVLSKL 121

Query: 117 -SLHRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMV 175
              H    V +  + Y L+        + +  R      +    D +        K + +
Sbjct: 122 WRPHAARMVPIFFFYYNLLKAATSAALLQAMQR-----ISFEATDTQSVIRKRHYKELFL 176

Query: 176 DLLKLVCYFLFALTCLPEGKPQL--LANASGPLVPLHVMVKALSPNPLHASNTVRGLLGL 233
             ++ + + ++A+T LP   P+L    N    +  ++ +  +L P  +      +GLLGL
Sbjct: 177 SFMEGIAFMVYAMTLLPSNAPRLREALNEGFWMDRVYSVFSSLCPQAVQVRPATQGLLGL 236

Query: 234 IASVC 238
           +A+  
Sbjct: 237 LATAP 241
>ref|XP_001568470.1| hypothetical protein LbrM34_V2.3670 [Leishmania braziliensis
           MHOM/BR/75/M2904]
 emb|CAM43584.1| hypothetical protein, conserved [Leishmania braziliensis]
          Length = 253

 Score =  263 bits (672), Expect = 1e-68,   Method: Composition-based stats.
 Identities = 72/250 (28%), Positives = 111/250 (44%), Gaps = 24/250 (9%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS 62
           A  + Y+ +  NRD+VM++VQF  MAL GPA  AGC  L+     +  +   YR +TR S
Sbjct: 11  ATFNDYIGNVSNRDRVMSVVQFSAMALTGPAAAAGCSKLSAHFNTIHHIAAHYRTITRFS 70

Query: 63  ---LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHG-----VF 114
              ++A AL+   +T       + +      +S  F   F + E   VLA        V 
Sbjct: 71  QWLVVAPALTYSGITGALNSHPNPLVGICKTISTAFFTVFLIGEEL-VLASKSNMLDPVL 129

Query: 115 PKSLHRLSGVAVLCWMYTLVLGIVRQL--YMLSKMRGHCTAAAASGDDKRKTCPYGGCKR 172
            K L+R+  V  L W       I R +  Y+L K   +        + K K         
Sbjct: 130 GKHLNRIRFV-FLFWS-----NIARLIMNYLLLKSSSYDAVKDTQNEKKAKDHRRKVLSV 183

Query: 173 VMVDLLKLVCYFLFALTCLPEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGL 230
               L  + CY L   +  P G P+ L+ A  SG +V +   + +L+P  +   +T +G+
Sbjct: 184 ADGVLQSMFCYTLLK-SSAPAG-PKYLSAALQSGNVVDV---ITSLAPPLIAVPSTPQGI 238

Query: 231 LGLIASVCEF 240
           +GL+ASV  F
Sbjct: 239 IGLVASVPGF 248
>ref|XP_804602.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN82751.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 161

 Score =  239 bits (610), Expect = 2e-61,   Method: Composition-based stats.
 Identities = 90/159 (56%), Positives = 118/159 (74%), Gaps = 5/159 (3%)

Query: 87  RIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLVLGIVRQLYMLSK 146
           R++Q+SH FHIGFCLNE+TAVLAG GV    L R  GVAV+CW+YTL+LGI RQ Y+L+K
Sbjct: 4   RLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTRFGGVAVVCWLYTLLLGIARQAYLLAK 63

Query: 147 M--RGHCTAAAASGDDKRKTCPYGG--CKRVMVDLLKLVCYFLFALTCLPEGKPQLLANA 202
              RG C A     D ++K  PY    CKR +V+L+K+ C+ +FA TCLPEG+P+LL + 
Sbjct: 64  HSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVNLVKMSCFAVFAKTCLPEGRPKLLQDV 122

Query: 203 SGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEFY 241
            GPLVPLH +++A++PN LH S+TVRGLL   AS+C+FY
Sbjct: 123 CGPLVPLHELIRAIAPNKLHLSDTVRGLLAATASLCDFY 161
>ref|XP_001469177.1| hypothetical protein [Leishmania infantum]
 emb|CAM72279.1| hypothetical protein, conserved [Leishmania infantum]
          Length = 253

 Score =  204 bits (520), Expect = 4e-51,   Method: Composition-based stats.
 Identities = 72/249 (28%), Positives = 109/249 (43%), Gaps = 24/249 (9%)

Query: 4   QAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS- 62
             + Y+ +A NRD+VM++VQF  MAL  PA  AGC  L+     +      YR VTR S 
Sbjct: 12  AFNDYVGNASNRDRVMSVVQFGAMALVAPAAAAGCPELSAHFDTILHGAAHYRTVTRFSQ 71

Query: 63  --LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGH-----GVFP 115
             ++A AL+   + S+     + +      +S  F   F + E   VLA        VF 
Sbjct: 72  WLVVAPALTPSGIKSVIASHPNPLVGICKTISTAFFTVFLIGEEL-VLASKCNMLDPVFG 130

Query: 116 KSLHRLSGVAVLCWMYTLVLGIVRQL--YMLSKMRGHCTAAAASGDDKRKTCPYGGCKRV 173
           +  +R+  V  L W       I R +  Y+L K   +     +  ++K K          
Sbjct: 131 RHFNRIRFV-FLFWS-----NIARLVMNYLLLKSSKYDAVKDSQNEEKAKDHRRKVLNVA 184

Query: 174 MVDLLKLVCYFLFALTCLPEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGLL 231
              L  + CY L   +  P G P+ L+ A  SG  V +   + +L+P      +T +G+L
Sbjct: 185 DGVLQSMFCYTLLK-SSAPAG-PKYLSAALRSGKAVDI---ITSLAPPLFVVPSTPQGML 239

Query: 232 GLIASVCEF 240
           GL ASV  F
Sbjct: 240 GLAASVPGF 248
>ref|XP_843474.1| hypothetical protein, conserved [Leishmania major strain Friedlin]
 gb|AAZ14592.1| hypothetical protein, conserved [Leishmania major strain Friedlin]
          Length = 253

 Score =  202 bits (515), Expect = 2e-50,   Method: Composition-based stats.
 Identities = 74/249 (29%), Positives = 109/249 (43%), Gaps = 24/249 (9%)

Query: 4   QAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS- 62
             + Y+ +A NRD+VM++VQF  MAL  PA  AGC  L+  L  +      YR VTR S 
Sbjct: 12  AFNNYVGNASNRDRVMSVVQFGAMALAAPAAAAGCPELSAHLSTILHGAAHYRTVTRFSQ 71

Query: 63  --LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGH-----GVFP 115
             ++A AL+   + S      +++      +S  F   F + E   VLA        V  
Sbjct: 72  WLVVAPALTPSGIKSAIASHPNLLVGICKTISTAFFTVFLIGEEL-VLASKCNMLDPVLG 130

Query: 116 KSLHRLSGVAVLCWMYTLVLGIVRQL--YMLSKMRGHCTAAAASGDDKRKTCPYGGCKRV 173
           K  +R+  V  L W       I R +  Y+L K   +        ++K K          
Sbjct: 131 KRFNRIRFV-FLFWS-----NIARLVMSYLLLKSSKYDAVKDNQNEEKAKDHRRKVLGVA 184

Query: 174 MVDLLKLVCYFLFALTCLPEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGLL 231
              L  + CY L   +  P G P+ L+ A  SG  V +   + +L+P  L   +T +G+L
Sbjct: 185 DGVLQSMFCYTLLK-SSAPAG-PKYLSAALRSGKAVDI---ITSLAPPLLVVPSTPQGML 239

Query: 232 GLIASVCEF 240
           GL ASV  F
Sbjct: 240 GLAASVPGF 248
>ref|XP_827421.1| hypothetical protein Tb09.211.2750 [Trypanosoma brucei TREU927]
 gb|EAN77091.1| hypothetical protein, conserved [Trypanosoma brucei]
          Length = 246

 Score =  107 bits (268), Expect = 7e-22,   Method: Composition-based stats.
 Identities = 50/250 (20%), Positives = 94/250 (37%), Gaps = 16/250 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MS+          +  +++A+ QF  +   G A +     +A S   LA++   Y  ++R
Sbjct: 1   MSSLPPDKTLFGSHSQRLVAVAQFCSLVSAGVAGSKHYTLVARSACALAKVLANYLCLSR 60

Query: 61  LS-----LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFP 115
           L      L   + S       S P+      R+  L+ L  + F + +  A+LA  GV  
Sbjct: 61  LKGSYLLLREVSPSSVRRRLHSSPSWFTGVMRV--LTMLAMLLFRITDKIALLANEGVLS 118

Query: 116 KS--LHRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRV 173
            +   +    +  L +   L+  +     + +         +    D R         + 
Sbjct: 119 NNICFYTSRLIPSLLFYCNLMQTMTSAALLKA-----VRPISFEATDTRNVFRKRYYLQG 173

Query: 174 MVDLLKLVCYFLFALTCLPEGKPQLL--ANASGPLVPLHVMVKALSPNPLHASNTVRGLL 231
           ++  L+ V    +A+T  P G P L    +    L     +  +  P  L  S T +GL+
Sbjct: 174 VLSFLEGVGLMTYAMTLFPRGVPPLAMTLHEKHLLTHWLAVAASSFPPALSVSTTTQGLI 233

Query: 232 GLIASVCEFY 241
           GL A++  F+
Sbjct: 234 GLAATLPSFF 243
>gb|ACO51908.1| Peroxisomal membrane protein 11C [Rana catesbeiana]
          Length = 235

 Score = 41.3 bits (96), Expect = 0.067,   Method: Composition-based stats.
 Identities = 31/138 (22%), Positives = 52/138 (37%), Gaps = 2/138 (1%)

Query: 15  RDKVMAIVQFLPMALEGPARTAGCES--LALSLGNLARMGDAYRAVTRLSLLANALSKPT 72
           RD++M  + +    L G       +      S   +A      R V RL    + L+   
Sbjct: 18  RDRLMRTLCYSCQLLGGVITQKHGDKQQYGKSFLIIASQLSHCRTVLRLFDDLSMLAYSF 77

Query: 73  LTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYT 132
              L K   D +   I  + ++F   +   E+ A  A  GV           +   W  +
Sbjct: 78  QYGLGKKEEDRLIRWISVIGNIFDQLYYPCEHVAWAADAGVIRTKSDIWWTASTALWGLS 137

Query: 133 LVLGIVRQLYMLSKMRGH 150
           L++GI+R L +L K+R  
Sbjct: 138 LLVGIIRSLRILLKLRRS 155
>ref|NP_001090009.1| hypothetical protein LOC735081 [Xenopus laevis]
 gb|AAH93545.1| MGC114945 protein [Xenopus laevis]
          Length = 236

 Score = 39.4 bits (91), Expect = 0.25,   Method: Composition-based stats.
 Identities = 40/206 (19%), Positives = 71/206 (34%), Gaps = 7/206 (3%)

Query: 15  RDKVMAIVQFLPMALEGPARTAGCE--SLALSLGNLARMGDAYRAVTRLSLLANALSKPT 72
           RD+V+  + +    L G          +   SL  ++      R V RL      L+   
Sbjct: 19  RDRVIRTLCYSCQLLGGVMSNKSKTEHNWGKSLLIVSSQLSHCRTVLRLFDDLAMLAYSV 78

Query: 73  LTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYT 132
                K   D +   I   S++    +   E+ A  A  GV           +   W  +
Sbjct: 79  KYGFGKKEKDSLIRWISIFSNISDQLYYPCEHIAWAADSGVIHAKSEMWWMASTALWGIS 138

Query: 133 LVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKLVCYFLFALTCLP 192
           L+LGIV+ L  L  +R +    +     K +       +  ++ ++  +     A+  +P
Sbjct: 139 LILGIVKSLRNLMMLRRYKGKNSKEEPPKSRGEIKSQIRSEVLCIISCLSDLFNAIHWMP 198

Query: 193 EGKPQLLANASG--PLVPLHVMVKAL 216
            G    L   S    LV L   + +L
Sbjct: 199 SG---FLWGGSSPTWLVGLMGTISSL 221
>ref|NP_611071.1| CG8315 CG8315-PA [Drosophila melanogaster]
 gb|AAF58084.1| CG8315-PA [Drosophila melanogaster]
 gb|AAL48984.1| RE39562p [Drosophila melanogaster]
          Length = 241

 Score = 38.2 bits (88), Expect = 0.49,   Method: Composition-based stats.
 Identities = 45/249 (18%), Positives = 83/249 (33%), Gaps = 49/249 (19%)

Query: 12  AWNRDKVMAIVQFLPMALEGPARTAGCE-SLALSLGNLARMGDAYRAVTRLSLLANALSK 70
           A  RDK+  ++Q+   A+     +A    +L  +   +  +   +R + R     +    
Sbjct: 11  AGGRDKIARLIQYASRAMWDSLESANSNPALVDNFKTVEYILSTFRKLLRFGKCVDVFYG 70

Query: 71  PTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWM 130
              T       D+       LS L    F   ++   LA  G+   +  R S +A   W+
Sbjct: 71  ALKTI---HHPDLNIRVTLTLSKLSQSLFLFADHFLWLARTGLTAVNAKRWSNIANKYWL 127

Query: 131 YTLVLGIVRQLY----MLSKMRGHCTAA--------------AASGDDKRKTCPYGGCKR 172
           +++++ + R  Y    +L   R    +                      +      G K 
Sbjct: 128 FSIIMNLCRDFYEILRVLDLHRSGSKSGISRCRIPASINSPEDFKRLALQSYVLMQGHKD 187

Query: 173 VMVDLLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLG 232
           ++VD +K  C F   LT L                       +L+P  +       GLLG
Sbjct: 188 IVVDTVKNACDFFIPLTAL--------------------GYTSLTPRTI-------GLLG 220

Query: 233 LIASVCEFY 241
            I+S+   +
Sbjct: 221 AISSLAGLW 229
>ref|XP_001321770.1| conserved hypothetical protein [Trichomonas vaginalis G3]
 gb|EAY09547.1| conserved hypothetical protein [Trichomonas vaginalis G3]
          Length = 1551

 Score = 37.1 bits (85), Expect = 1.1,   Method: Composition-based stats.
 Identities = 27/147 (18%), Positives = 51/147 (34%), Gaps = 19/147 (12%)

Query: 47  NLARMGDAYRAVTRLSLLANALSKPTLTSLSKPTGDMVASRID---QLSHLFHIGFCLNE 103
           +L  +   Y  +T+ + +AN+L + T++  + P  +M    +D   Q+S  F        
Sbjct: 232 SLQSIYYGYYFITQHTYVANSLIEGTISKPNIPHPNMFGPILDKFIQISTEFFEKM---- 287

Query: 104 NTAVLAGHGVFPKSL-----HRLSGVAVLCWMYTLVLGIVRQLYML------SKMRGHCT 152
            TA+ +G G               GV + C+ YT+  G      ++             +
Sbjct: 288 KTAISSGEGETAYQPAVYFAQSFRGV-LFCYFYTIQQGDTNLDKLIEDVVSTLIQSTRLS 346

Query: 153 AAAASGDDKRKTCPYGGCKRVMVDLLK 179
                   K K       K +   + K
Sbjct: 347 LGDEQAKTKLKNHTKAIEKYLEQTVQK 373
>gb|EEH53081.1| predicted protein [Micromonas pusilla CCMP1545]
          Length = 233

 Score = 36.7 bits (84), Expect = 1.5,   Method: Composition-based stats.
 Identities = 28/150 (18%), Positives = 51/150 (34%), Gaps = 8/150 (5%)

Query: 15  RDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLT 74
           +DK +A++Q++ M   G    AG  +LA+   +L      +R    +  L   L+  TL 
Sbjct: 25  KDKAIALLQYVAMFASG--GEAG-TALAIQ-KSLGAARKPFRVFKPIETLMPLLTGATLR 80

Query: 75  SLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLV 134
              +  G  +A  +  +  L    +   ++       GV            V  W + L 
Sbjct: 81  GGKRRPGQDLARALSLVKTLGMTFYFAADHVVWAGAAGVLSDKSLAQRAQKVSYWSWCL- 139

Query: 135 LGIVRQLYMLSKMRGHCTAAAASGDDKRKT 164
                   + +  R    A  A     +K 
Sbjct: 140 ---ASLAGLATATRELTDALDAMTAATKKD 166
>ref|XP_001838198.1| hypothetical protein CC1G_07939 [Coprinopsis cinerea okayama7#130]
 gb|EAU83566.1| hypothetical protein CC1G_07939 [Coprinopsis cinerea okayama7#130]
          Length = 1786

 Score = 36.7 bits (84), Expect = 1.6,   Method: Composition-based stats.
 Identities = 26/105 (24%), Positives = 40/105 (38%), Gaps = 5/105 (4%)

Query: 53  DAYRAVTRLSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHG 112
           DAY     L LLAN+  KP    L           ++ +   +H  F  +E   +L  H 
Sbjct: 145 DAYSVFEDLCLLANS-EKPRFLKLESLHKTFALELVESVLTNYHGLFRKHEEMILLLRHH 203

Query: 113 VFPKSLHRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAAS 157
           + P  L  +S   +      L+L   R +++L K   H     A 
Sbjct: 204 LCPLLLKTVSERPIF----PLILRCTRVIFLLLKQFSHELETEAE 244
>gb|EDN36632.1| predicted protein [Francisella tularensis subsp. novicida
          GA99-3549]
          Length = 246

 Score = 36.7 bits (84), Expect = 1.6,   Method: Composition-based stats.
 Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 6/52 (11%)

Query: 38 CESLALSLGNLARMGDAY----RAVTRLSLLANALSKPTLTSLSKPTGDMVA 85
          C+ L  SL NL R+   Y    R +  + +L +++S PT+  +SK   D++ 
Sbjct: 17 CDKL--SLNNLLRILANYNIQARNIKFIPVLFSSVSTPTILGISKSHNDILV 66
>ref|NP_651137.3| CG13827 CG13827-PA [Drosophila melanogaster]
 gb|AAM29451.1| RE30473p [Drosophila melanogaster]
 gb|AAF56119.2| CG13827-PA [Drosophila melanogaster]
          Length = 233

 Score = 36.3 bits (83), Expect = 1.9,   Method: Composition-based stats.
 Identities = 35/183 (19%), Positives = 67/183 (36%), Gaps = 4/183 (2%)

Query: 13  WNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPT 72
             RDKVM  + +    + G       E LA      +      RA  RL      +    
Sbjct: 19  GGRDKVMKALCYSAKLVAGYHAKRNPE-LAKRYATASSRISGARATLRLIDDIPMIQYAL 77

Query: 73  LTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFP-KSLHRLSGVAVLCWMY 131
              L +   D V   +   +++  + +   E    LA H +   K+      V  + W+ 
Sbjct: 78  EYGLGENEPDRVMQVLGVTANIVDLLYYPIEKVCWLAEHKIVDVKNADNWDNVNSIFWVL 137

Query: 132 TLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKLVCYFLFALTCL 191
           ++ L ++R +   S  +          +   KT      +  MV ++++   F+ A++ L
Sbjct: 138 SVYLNLMRTMRNFSLNQEKLNRTNNINELDVKTLTKHRLE--MVSIVRISLDFVHAVSTL 195

Query: 192 PEG 194
           P+G
Sbjct: 196 PKG 198
>ref|ZP_01390434.1| DNA polymerase III, alpha subunit [Geobacter sp. FRC-32]
 gb|EAT60281.1| DNA polymerase III, alpha subunit [Geobacter sp. FRC-32]
          Length = 1156

 Score = 36.3 bits (83), Expect = 1.9,   Method: Composition-based stats.
 Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 13/97 (13%)

Query: 7   TYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLAN 66
            Y+ + + RDKV  I+ F  MA  G  R  G  +L +S          Y  V R++ L  
Sbjct: 427 QYVTEKYGRDKVCQIITFGTMAARGVLRDVG-RALDMS----------YGDVDRIAKLVP 475

Query: 67  ALSKPTLTSLSK--PTGDMVASRIDQLSHLFHIGFCL 101
            +   TL    +  P  + +A    ++  L  +  CL
Sbjct: 476 EVLGITLEKALQQEPKLNELAEADPRIKELLDVALCL 512
>ref|NP_001006340.1| peroxisomal biogenesis factor 11 gamma [Gallus gallus]
 emb|CAG32021.1| hypothetical protein [Gallus gallus]
          Length = 237

 Score = 36.3 bits (83), Expect = 2.1,   Method: Composition-based stats.
 Identities = 49/211 (23%), Positives = 79/211 (37%), Gaps = 16/211 (7%)

Query: 15  RDKVMAIV----QFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSK 70
           RD+V+  +    Q    AL G    A  E L  SL  ++    + R V RL      LS 
Sbjct: 19  RDRVVRALCYGCQLAGGALAGTQSPA--EGLPGSLLAVSAQLSSCRTVLRLLDDFAMLSH 76

Query: 71  PTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWM 130
                L     D +   +  L ++    +   E+ A  A  GV      R    +   W 
Sbjct: 77  SRAYGLGPKDEDALVRGLSVLCNVADQLYYPCEHVAWAADTGVIRGRSQRWWAASTALWG 136

Query: 131 YTLVLGIVRQLYMLSKMR---GHCTAAAASGDDKRKTCPYGGCKRVMVDLLKLVCYFLFA 187
            +L+LG +R L +L ++R          AS   ++KT      K  +++++  +     A
Sbjct: 137 LSLLLGTLRSLRILFQLRRKLRQQKRTPASPQSQQKT--RAQVKAEVLNIVSNLADLSNA 194

Query: 188 LTCLPEGKPQLLANASG--PLVPLHVMVKAL 216
           +  LP   P  L        LV L   + +L
Sbjct: 195 VHWLP---PGFLWAGRFPPWLVGLLGTISSL 222
>ref|XP_001239782.1| hypothetical protein CIMG_09403 [Coccidioides immitis RS]
 gb|EAS28199.1| hypothetical protein CIMG_09403 [Coccidioides immitis RS]
          Length = 415

 Score = 35.9 bits (82), Expect = 2.3,   Method: Composition-based stats.
 Identities = 34/143 (23%), Positives = 51/143 (35%), Gaps = 26/143 (18%)

Query: 48  LARMGDAYRAVTRLSLLANALSKPTLTSL----------------SKPTGDMVASRIDQL 91
           L+   D  ++ TR  L   +L   T T+L                  P  D V   +   
Sbjct: 207 LSASADDSKSQTRPLLALASLISETRTALRLLGLIPLWEWGSATVKSPPADPVLRSVAFA 266

Query: 92  SHLFHIGFCLNENTAVLAGHGVFPKS-LHRLSGVAVLC------WMYTLVLGIVRQ---L 141
               ++ +   EN A LA  GV  +  L RL GV          W+  +VL  VR     
Sbjct: 267 QVFVNVIYQFMENVAFLASKGVVSQRLLQRLGGVGKWYIWSTRAWLGHVVLEFVRLWRER 326

Query: 142 YMLSKMRGHCTAAAASGDDKRKT 164
            + ++      A A+S DD+   
Sbjct: 327 SLAARQNELALAKASSPDDRLSD 349
>ref|YP_702234.1| D-serine/D-alanine/glycine transporter, APC family [Rhodococcus sp.
           RHA1]
 gb|ABG94076.1| D-serine/D-alanine/glycine transporter, APC family protein
           [Rhodococcus sp. RHA1]
          Length = 490

 Score = 35.9 bits (82), Expect = 2.7,   Method: Composition-based stats.
 Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 16/124 (12%)

Query: 21  IVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS---LLANALSKPTLTSLS 77
           ++QF+ +     +  +G  S +  +  LA+ GDA   + RLS   + ANAL       LS
Sbjct: 308 VIQFVVLTSAASSANSGIYSTSRMVYGLAQEGDAPGRLGRLSSRKVPANALMFSCAFLLS 367

Query: 78  K----PTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKS---LHRLS-----GVA 125
                 +GD V      ++ +  + F     T +LA + V+ K    LH  S     G  
Sbjct: 368 AIALLFSGDSVIEAFTTVTTISSVLFMFVW-TMILASYIVYRKRRPELHEASKFKMPGGV 426

Query: 126 VLCW 129
           V+CW
Sbjct: 427 VMCW 430
>ref|XP_394365.2| PREDICTED: similar to CG8315-PA isoform 1 [Apis mellifera]
 ref|XP_623134.1| PREDICTED: similar to CG8315-PA isoform 2 [Apis mellifera]
          Length = 232

 Score = 35.6 bits (81), Expect = 3.3,   Method: Composition-based stats.
 Identities = 41/237 (17%), Positives = 91/237 (38%), Gaps = 40/237 (16%)

Query: 15  RDKVMAIVQFLPMALEGPA-RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTL 73
           RD+++ ++Q+   A    A ++   ++ A  L +L     ++R + RL    ++L    L
Sbjct: 14  RDRIIRLLQYGSRAYWYYAQKSHSTQNSAEILRSLEYTFSSFRKLLRLGRCLDSL-YSAL 72

Query: 74  TSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTL 133
             +  P  ++       LS + +  F L ++   +   G+   ++ + S +A   W+  +
Sbjct: 73  KMMKYP--EVTIRVTLTLSKIANALFLLADHIIWIGRVGLLRVNIKKWSKIANKYWLMNI 130

Query: 134 VLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGC---------KRVMVDLLKLVCYF 184
           ++ + R +Y + K+  +          K  +  +            K +++D +K  C  
Sbjct: 131 IMNLTRDIYEIIKIFENEGKDVLIRTPKFSSNLWRQYELLYHLKNHKNIVIDTIKNGCDM 190

Query: 185 LFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEFY 241
              LT L                        L+P  +       G+LG+I+S+   Y
Sbjct: 191 FIPLTAL--------------------GFTKLTPGTI-------GILGMISSIVSIY 220
>ref|XP_001358348.1| GA12553-PA [Drosophila pseudoobscura]
 gb|EAL27487.1| GA12553-PA [Drosophila pseudoobscura]
          Length = 233

 Score = 35.6 bits (81), Expect = 3.4,   Method: Composition-based stats.
 Identities = 34/185 (18%), Positives = 68/185 (36%), Gaps = 8/185 (4%)

Query: 13  WNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPT 72
             RDKVM  + +    + G       + LA      +      RA  RL      +    
Sbjct: 19  GGRDKVMKALCYSAKLVAGYHAKRNPD-LAKRYATASSKISGARATLRLIDDIPMIQYAL 77

Query: 73  LTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFP-KSLHRLSGVAVLCWMY 131
              L +   D V + +   +++  + +   E    LA H +   K+  R   V  + W+ 
Sbjct: 78  EYGLGENEPDRVMAVLGVTANIVDLLYYPIEKVCWLAEHKIVDVKNADRWDNVNSIFWVL 137

Query: 132 TLVLGIVRQL--YMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKLVCYFLFALT 189
           ++ L ++R +  + L++ +  C    +  D               V + ++   F+ A++
Sbjct: 138 SVYLNLMRTMRNFSLNQEKLSCNPKLSDIDATVLAKHRLEL----VSIARISLDFVHAVS 193

Query: 190 CLPEG 194
            LP G
Sbjct: 194 TLPGG 198
>ref|XP_954194.1| DEAD-box helicase, putative [Theileria annulata strain Ankara]
 emb|CAI73517.1| DEAD-box helicase, putative [Theileria annulata]
          Length = 1925

 Score = 35.2 bits (80), Expect = 3.8,   Method: Composition-based stats.
 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 12/86 (13%)

Query: 75   SLSKPTGDM---------VASRIDQLSHL--FHIGFCLNENTAVLAG-HGVFPKSLHRLS 122
             +SKP G           +A  +D+++H   FH  F +N++T V+ G   V+ +S H   
Sbjct: 1820 GISKPKGGKYTISSDVVNLAVMLDEINHTTEFHYLFLVNQSTNVIYGYKKVYKQSTHSFK 1879

Query: 123  GVAVLCWMYTLVLGIVRQLYMLSKMR 148
             V ++ ++  L + I   L +L  + 
Sbjct: 1880 YVLIIFYLLRLRIDIGSNLTLLLILS 1905
>ref|NP_784281.1| fucose transport protein [Lactobacillus plantarum WCFS1]
 emb|CAD63122.1| fucose transport protein [Lactobacillus plantarum WCFS1]
          Length = 454

 Score = 35.2 bits (80), Expect = 4.2,   Method: Composition-based stats.
 Identities = 20/78 (25%), Positives = 31/78 (39%), Gaps = 5/78 (6%)

Query: 124 VAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKLVCY 183
           V +L   Y +          ++KM G    A      ++   PY     V+     LV  
Sbjct: 169 VGILLGKYLIFNDGASLATTMAKMHGAARLAYGQRMLQQTLLPYKYLIVVL-----LVAI 223

Query: 184 FLFALTCLPEGKPQLLAN 201
           F+F LT  P GKP+  ++
Sbjct: 224 FIFVLTQFPSGKPKQRSD 241
>ref|XP_001215122.1| predicted protein [Aspergillus terreus NIH2624]
 gb|EAU33705.1| predicted protein [Aspergillus terreus NIH2624]
          Length = 956

 Score = 34.8 bits (79), Expect = 5.1,   Method: Composition-based stats.
 Identities = 20/97 (20%), Positives = 35/97 (36%), Gaps = 2/97 (2%)

Query: 72  TLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGV-AVLCWM 130
            L   +   G ++ + I+ +       + L E+  +L    ++P   ++   V A   W 
Sbjct: 235 GLLGGNSSDGFLLLA-IELVRWSCLGLYFLLEDLTILHAMNIYPVPWNKPVLVEAYKFWF 293

Query: 131 YTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPY 167
           Y L L IV  L+ L            S  +K K    
Sbjct: 294 YALSLSIVSSLWRLVFSTEQPATTKQSKGEKAKAATK 330
>ref|NP_542393.1| peroxisomal biogenesis factor 11 gamma [Homo sapiens]
 sp|Q96HA9|PX11C_HUMAN Peroxisomal membrane protein 11C (Peroxin-11C) (Peroxisomal
           biogenesis factor 11C) (PEX11gamma) (Pex11pgamma)
 gb|AAH08780.1| Peroxisomal biogenesis factor 11 gamma [Homo sapiens]
 dbj|BAD01558.1| peroxin Pex11p gamma [Homo sapiens]
 gb|EAW69038.1| peroxisomal biogenesis factor 11 gamma, isoform CRA_b [Homo
           sapiens]
          Length = 241

 Score = 34.8 bits (79), Expect = 5.6,   Method: Composition-based stats.
 Identities = 30/141 (21%), Positives = 52/141 (36%), Gaps = 12/141 (8%)

Query: 15  RDKVMAIVQFLPMALEG------PART-AGCESLALSLGNLARMGDAYRAVTRLSLLANA 67
           RD+++ ++ +    + G      PAR+  G   L      ++      R + RL      
Sbjct: 17  RDRLIRVLGYCCQLVGGVLVEQCPARSEVGTRLLV-----VSTQLSHCRTILRLFDDLAM 71

Query: 68  LSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVL 127
                   L     D     +  L +L    +   E+ A  A   V      R   ++  
Sbjct: 72  FVYTKQYGLGAQEEDAFVRCVSVLGNLADQLYYPCEHVAWAADARVLHVDSSRWWTLSTT 131

Query: 128 CWMYTLVLGIVRQLYMLSKMR 148
            W  +L+LG+ R L+ML K+R
Sbjct: 132 LWALSLLLGVARSLWMLLKLR 152
>gb|AAU08775.1| cytochrome b [Rhinogobius sp. YB]
          Length = 380

 Score = 34.4 bits (78), Expect = 6.7,   Method: Composition-based stats.
 Identities = 28/131 (21%), Positives = 41/131 (31%), Gaps = 24/131 (18%)

Query: 122 SGVAVLCWMYTLVLGIVRQLYMLSKMRGHCT-AAAASGDDKRKTCPYGGCKRVMVDLLKL 180
              A    +  +VL       +     G    A   S  DK    PY   K ++      
Sbjct: 177 RFFAFHFLLPFVVLAATMLHLLFLHETGSNNPAGLNSDADKIPFHPYFSYKDLL-----G 231

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLH--------------ASNT 226
               L ALTCL    P  L +      P + +V    P  +                 N 
Sbjct: 232 FAIMLLALTCLALFSPNYLGDPD-NFTPANPLVT---PPHIKPEWYFLFAYAILRSIPNK 287

Query: 227 VRGLLGLIASV 237
           + G+L L+AS+
Sbjct: 288 LGGVLALLASI 298
>gb|AAU08771.1| cytochrome b [Rhinogobius sp. YB]
 gb|AAU08773.1| cytochrome b [Rhinogobius sp. YB]
 gb|AAU08774.1| cytochrome b [Rhinogobius sp. YB]
          Length = 380

 Score = 34.4 bits (78), Expect = 6.8,   Method: Composition-based stats.
 Identities = 28/131 (21%), Positives = 41/131 (31%), Gaps = 24/131 (18%)

Query: 122 SGVAVLCWMYTLVLGIVRQLYMLSKMRGHCT-AAAASGDDKRKTCPYGGCKRVMVDLLKL 180
              A    +  +VL       +     G    A   S  DK    PY   K ++      
Sbjct: 177 RFFAFHFLLPFVVLAATMLHLLFLHETGSNNPAGLNSDADKIPFHPYFSYKDLL-----G 231

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLH--------------ASNT 226
               L ALTCL    P  L +      P + +V    P  +                 N 
Sbjct: 232 FAIMLLALTCLALFSPNYLGDPD-NFTPANPLVT---PPHIKPEWYFLFAYAILRSIPNK 287

Query: 227 VRGLLGLIASV 237
           + G+L L+AS+
Sbjct: 288 LGGVLALLASI 298
>ref|XP_317688.3| AGAP007812-PA [Anopheles gambiae str. PEST]
 gb|EAA12812.3| AGAP007812-PA [Anopheles gambiae str. PEST]
          Length = 220

 Score = 34.4 bits (78), Expect = 7.1,   Method: Composition-based stats.
 Identities = 46/234 (19%), Positives = 88/234 (37%), Gaps = 47/234 (20%)

Query: 15  RDKVMAIVQFLPMALEGPARTAGCESLA--LSLGNLARMGDAYRAVTRL----SLLANAL 68
           +DK+  + Q+   AL   A   G ES+     L ++  +  ++R + R      +L +A 
Sbjct: 14  KDKIARLCQYSCRALW--ASKDGSESIETVQLLKHIESILSSFRKLLRFGKGFEVLYSAT 71

Query: 69  SKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGV--AV 126
           +   L  LS       A     L  +    F L ++   L+  G+  K+++    V  + 
Sbjct: 72  AGLKLKELS-------AQLFITLGKIASGLFLLADHVVWLSRSGI-NKNINTSKWVDRSN 123

Query: 127 LCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCP-YGGCKRVMVDLLKLVCYFL 185
             W+ +++  + R                    D ++    +    R  +  L+   Y +
Sbjct: 124 RFWLISILFNLCR--------------------DVQELYRLFVYYSRSNIRNLQRTLYAV 163

Query: 186 FALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCE 239
           +      E KP LL +    +  + + +  L    L  SN   GLLG I+S+  
Sbjct: 164 YR-----ENKP-LLVDTIKNVCDVFIPLNGLG--ILPVSNQTIGLLGAISSLMG 209
>gb|AAU08772.1| cytochrome b [Rhinogobius sp. YB]
 gb|AAU08776.1| cytochrome b [Rhinogobius sp. YB]
 gb|AAU08777.1| cytochrome b [Rhinogobius sp. BB]
 gb|AAU08778.1| cytochrome b [Rhinogobius sp. BB]
 gb|AAU08779.1| cytochrome b [Rhinogobius sp. BB]
 gb|AAU08780.1| cytochrome b [Rhinogobius sp. BB]
 gb|AAU08781.1| cytochrome b [Rhinogobius sp. BB]
 gb|AAU08782.1| cytochrome b [Rhinogobius sp. BB]
          Length = 380

 Score = 34.4 bits (78), Expect = 7.2,   Method: Composition-based stats.
 Identities = 28/131 (21%), Positives = 41/131 (31%), Gaps = 24/131 (18%)

Query: 122 SGVAVLCWMYTLVLGIVRQLYMLSKMRGHCT-AAAASGDDKRKTCPYGGCKRVMVDLLKL 180
              A    +  +VL       +     G    A   S  DK    PY   K ++      
Sbjct: 177 RFFAFHFLLPFVVLAATMLHLLFLHETGSNNPAGLNSDADKIPFHPYFSYKDLL-----G 231

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLH--------------ASNT 226
               L ALTCL    P  L +      P + +V    P  +                 N 
Sbjct: 232 FAIMLLALTCLALFSPNYLGDPD-NFTPANPLVT---PPHIKPEWYFLFAYAILRSIPNK 287

Query: 227 VRGLLGLIASV 237
           + G+L L+AS+
Sbjct: 288 LGGVLALLASI 298
>gb|ABF19672.1| cytochrome b [Ctenogobiops feroculus]
          Length = 332

 Score = 34.4 bits (78), Expect = 7.2,   Method: Composition-based stats.
 Identities = 26/131 (19%), Positives = 41/131 (31%), Gaps = 24/131 (18%)

Query: 122 SGVAVLCWMYTLVLGIVRQLYMLSKMRGHCT-AAAASGDDKRKTCPYGGCKRVMVDLLKL 180
              A    +  ++L       +     G    A   S  DK    PY   K ++      
Sbjct: 153 RFFAFHFLLPFVILAATVLHLLFLHQTGSNNPAGINSDTDKVPFHPYFSYKDLL-----G 207

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLH--------------ASNT 226
               L ALT L    P  L +     +P + +V    P  +                 N 
Sbjct: 208 FAIMLLALTSLALFTPNYLGDPD-NFIPANPLVT---PPHIKPEWYFLFAYAILRSIPNK 263

Query: 227 VRGLLGLIASV 237
           + G+L L+AS+
Sbjct: 264 LGGVLALLASI 274
>ref|YP_001231258.1| DNA polymerase III, alpha subunit [Geobacter uraniireducens Rf4]
 gb|ABQ26685.1| DNA polymerase III, alpha subunit [Geobacter uraniireducens Rf4]
          Length = 1157

 Score = 34.4 bits (78), Expect = 7.3,   Method: Composition-based stats.
 Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 15/98 (15%)

Query: 7   TYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGD-AYRAVTRLSLLA 65
            Y+ + + RDKV  I+ F  MA  G  R  G            R  D AY  V +++ L 
Sbjct: 427 QYVTEKYGRDKVCQIITFGTMAARGVLRDVG------------RALDMAYGDVDKIAKLV 474

Query: 66  NALSKPTLTSLSK--PTGDMVASRIDQLSHLFHIGFCL 101
             +   TL    +  P  + +A+   ++  L  +  CL
Sbjct: 475 PEVLGITLDKALQQEPKLNELAAADRRVKELLDVALCL 512
>gb|AAO34460.1|AF454888_1 cytochrome b [Moxostoma breviceps]
          Length = 380

 Score = 34.0 bits (77), Expect = 8.6,   Method: Composition-based stats.
 Identities = 31/144 (21%), Positives = 50/144 (34%), Gaps = 28/144 (19%)

Query: 110 GHGVFPKSLHRLSGVAVLCWMYTLVLGIVRQLYMLSKMR--GHCTAAAASGDDKRKTCPY 167
           G  V+  +L R        ++  LV+     +++L       +  A   S  DK    PY
Sbjct: 167 GFSVYNATLTRF---FAFHFLLPLVIAGATIIHLLFLHETGSNNPAGINSDADKISFHPY 223

Query: 168 GGCKRVMVDLLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLH----- 222
              K ++          L ALT L    P LL +      P + +V    P  +      
Sbjct: 224 FSYKDLL-----GFAAMLLALTSLALFSPNLLGDPD-NFTPANPVVT---PPHIKPEWYF 274

Query: 223 ---------ASNTVRGLLGLIASV 237
                      N + G+L L+AS+
Sbjct: 275 LFAYAILRSIPNKLGGVLALLASI 298
>ref|XP_001497087.1| PREDICTED: similar to Peroxisomal biogenesis factor 11 gamma [Equus
           caballus]
          Length = 240

 Score = 34.0 bits (77), Expect = 9.1,   Method: Composition-based stats.
 Identities = 32/141 (22%), Positives = 53/141 (37%), Gaps = 12/141 (8%)

Query: 15  RDKVMAIVQFLPMALEGP------ART-AGCESLALSLGNLARMGDAYRAVTRLSLLANA 67
           RD+++  + +    + G       AR+  G   LA     L+      R V RL   A  
Sbjct: 17  RDRLIRTLGYCCQLVGGVLVQQCRARSEVGTRLLA-----LSSQLSHCRTVLRLFDDAAM 71

Query: 68  LSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVL 127
                   L     D+    +  L +L    +   E+ A  A   +      R   ++  
Sbjct: 72  FVYTKQYGLGAEEEDIFVRCVSVLGNLADQLYYPCEHVAWAADAKILRVDSARWWTLSTA 131

Query: 128 CWMYTLVLGIVRQLYMLSKMR 148
            W  +L+LGI R L+M+ K+R
Sbjct: 132 FWGLSLLLGIARSLWMVLKLR 152
>ref|NP_001072770.1| hypothetical protein LOC780227 [Xenopus tropicalis]
 gb|AAI25807.1| Hypothetical protein MGC147616 [Xenopus tropicalis]
          Length = 149

 Score = 34.0 bits (77), Expect = 10.0,   Method: Composition-based stats.
 Identities = 29/127 (22%), Positives = 45/127 (35%), Gaps = 2/127 (1%)

Query: 15  RDKVMAIVQFLPMALEGPARTAGC--ESLALSLGNLARMGDAYRAVTRLSLLANALSKPT 72
           RD+V+  + +    L G          +   SL  +A      R V RL      L+   
Sbjct: 20  RDRVVRKLCYSCQLLGGVMSNKSEVDHNWGKSLLVVASQLSHCRTVLRLFDDLAMLAYSV 79

Query: 73  LTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYT 132
              L K   D +   I   S++    +   E+ A  A  GV           +   W  +
Sbjct: 80  NYGLGKKEKDPIIRWISIFSNISDQLYYPCEHIAWAADSGVISAKSEIWWTASTAFWGLS 139

Query: 133 LVLGIVR 139
           L+LGIV+
Sbjct: 140 LILGIVK 146
Searching..................................................done Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|XP_827420.1|  Gim5B protein [Trypanosoma brucei TREU927]...   378   e-103
emb|CAB94857.1|  GIM5B protein [Trypanosoma brucei brucei]        377   e-103
emb|CAB94856.1|  GIM5A protein [Trypanosoma brucei brucei]        357   5e-97
ref|XP_827419.1|  Gim5A protein [Trypanosoma brucei TREU927]...   354   4e-96
ref|XP_821649.1|  Gim5A protein, putative [Trypanosoma cruzi...   354   5e-96
ref|XP_804598.1|  Gim5A protein, putative [Trypanosoma cruzi...   353   7e-96
ref|XP_811903.1|  Gim5A protein, putative [Trypanosoma cruzi...   319   2e-85
ref|XP_843475.1|  glycosomal membrane protein [Leishmania ma...   300   7e-80
ref|XP_001469178.1|  Gim5A protein; glycosomal membrane prot...   296   1e-78
ref|XP_001568471.1|  Gim5A protein, putative [Leishmania bra...   295   2e-78
ref|XP_804601.1|  hypothetical protein Tc00.1047053510669.9 ...   267   6e-70
ref|XP_001568470.1|  hypothetical protein LbrM34_V2.3670 [Le...   257   5e-67
ref|XP_811904.1|  hypothetical protein Tc00.1047053507009.20...   256   7e-67
ref|XP_827421.1|  hypothetical protein Tb09.211.2750 [Trypan...   248   2e-64
ref|XP_001469177.1|  hypothetical protein [Leishmania infant...   236   1e-60
ref|XP_843474.1|  hypothetical protein, conserved [Leishmani...   227   6e-58
ref|XP_804602.1|  Gim5A protein, putative [Trypanosoma cruzi...   226   2e-57
Sequences not found previously or not previously below threshold:

gb|ACO51908.1|  Peroxisomal membrane protein 11C [Rana cates...    38   0.48 
ref|XP_394365.2|  PREDICTED: similar to CG8315-PA isoform 1 ...    38   0.54 
gb|EDN36632.1|  predicted protein [Francisella tularensis su...    36   1.8  
ref|NP_784281.1|  fucose transport protein [Lactobacillus pl...    36   2.0  
ref|YP_001365955.1|  integral membrane sensor hybrid histidi...    36   3.6  
ref|YP_001050131.1|  integral membrane sensor hybrid histidi...    36   3.7  
ref|YP_001554223.1|  integral membrane sensor hybrid histidi...    36   3.7  
ref|XP_001838198.1|  hypothetical protein CC1G_07939 [Coprin...    35   3.8  
ref|ZP_00834525.1|  hypothetical protein YintA_01001073 [Yer...    35   3.9  
dbj|BAC26361.1|  unnamed protein product [Mus musculus]            35   4.2  
gb|AAN77886.1|  ribosomal protein S4 [Myxine glutinosa]            35   4.4  
ref|ZP_01707330.1|  periplasmic sensor hybrid histidine kina...    35   4.5  
gb|EEH53081.1|  predicted protein [Micromonas pusilla CCMP1545]    35   4.6  
gb|EAW54524.1|  KIAA0913, isoform CRA_d [Homo sapiens]             35   4.7  
ref|NP_611071.1|  CG8315 CG8315-PA [Drosophila melanogaster]...    35   4.9  
dbj|BAA74936.1|  KIAA0913 protein [Homo sapiens]                   35   4.9  
ref|YP_963051.1|  integral membrane sensor hybrid histidine ...    35   4.9  
ref|XP_001365228.1|  PREDICTED: hypothetical protein [Monode...    35   5.5  
ref|XP_507850.2|  PREDICTED: hypothetical protein isoform 2 ...    35   6.1  
ref|NP_055852.2|  hypothetical protein LOC23053 [Homo sapien...    35   6.1  
sp|A7E2V4|K0913_HUMAN  Zinc finger SWIM domain-containing pr...    35   6.1  
ref|NP_082272.1|  hypothetical protein LOC268721 [Mus muscul...    35   6.2  
ref|XP_536393.2|  PREDICTED: similar to CG32542-PA isoform 2...    35   6.2  
gb|EDL01494.1|  mCG121327 [Mus musculus]                           35   6.3  
ref|XP_001099765.1|  PREDICTED: similar to CG32542-PA isofor...    35   6.3  
ref|XP_001605353.1|  PREDICTED: similar to ATP-binding casse...    35   6.3  
dbj|BAG10398.1|  KIAA0913 protein [synthetic construct]            35   6.3  
ref|NP_597415.1|  SERINE PALMITOYL TRANSFERASE SUBUNIT 2 [En...    34   6.5  
ref|XP_341280.2|  PREDICTED: similar to CG32542-PA [Rattus n...    34   6.6  
gb|AAH85161.1|  2310021P13Rik protein [Mus musculus]               34   6.8  
ref|XP_001146127.1|  PREDICTED: hypothetical protein isoform...    34   6.8  
gb|EDL86245.1|  similar to KIAA0913 protein (predicted) [Rat...    34   7.5  
ref|ZP_01843674.1|  integral membrane sensor hybrid histidin...    34   9.4  
CONVERGED!
>ref|XP_827420.1| Gim5B protein [Trypanosoma brucei TREU927]
 gb|EAN77090.1| Gim5B protein [Trypanosoma brucei]
          Length = 241

 Score =  378 bits (972), Expect = e-103,   Method: Composition-based stats.
 Identities = 241/241 (100%), Positives = 241/241 (100%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
           VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF
Sbjct: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240

Query: 241 Y 241
           Y
Sbjct: 241 Y 241
>emb|CAB94857.1| GIM5B protein [Trypanosoma brucei brucei]
          Length = 241

 Score =  377 bits (970), Expect = e-103,   Method: Composition-based stats.
 Identities = 240/241 (99%), Positives = 240/241 (99%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKP GDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPAGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
           VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF
Sbjct: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240

Query: 241 Y 241
           Y
Sbjct: 241 Y 241
>emb|CAB94856.1| GIM5A protein [Trypanosoma brucei brucei]
          Length = 243

 Score =  357 bits (916), Expect = 5e-97,   Method: Composition-based stats.
 Identities = 218/243 (89%), Positives = 224/243 (92%), Gaps = 2/243 (0%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRG-HCTAAAASGDDKR-KTCPYGGCKRVMVDLL 178
           LSGVAVLCWMYTLVLGIVRQLY+  K+R    +  A +GDDK+     Y   KR  V+LL
Sbjct: 121 LSGVAVLCWMYTLVLGIVRQLYLFVKLRPRQASRGAGAGDDKKVPAYTYLELKRAFVNLL 180

Query: 179 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 238
           KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC
Sbjct: 181 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 240

Query: 239 EFY 241
           EFY
Sbjct: 241 EFY 243
>ref|XP_827419.1| Gim5A protein [Trypanosoma brucei TREU927]
 gb|EAN77089.1| Gim5A protein [Trypanosoma brucei]
          Length = 243

 Score =  354 bits (908), Expect = 4e-96,   Method: Composition-based stats.
 Identities = 216/243 (88%), Positives = 222/243 (91%), Gaps = 2/243 (0%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR
Sbjct: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR
Sbjct: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRG-HCTAAAASGDDKR-KTCPYGGCKRVMVDLL 178
           LSGVAVLCWMYTL LGIVRQLY+  K+R    +  A +GDDK+     Y   KR  V+LL
Sbjct: 121 LSGVAVLCWMYTLALGIVRQLYLFVKLRPRQASRGAGAGDDKKVPAYTYLELKRAFVNLL 180

Query: 179 KLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 238
           KLVCYFLFALTCLPEGKPQLLANA GPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC
Sbjct: 181 KLVCYFLFALTCLPEGKPQLLANARGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVC 240

Query: 239 EFY 241
           EFY
Sbjct: 241 EFY 243
>ref|XP_821649.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN99798.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 244

 Score =  354 bits (908), Expect = 5e-96,   Method: Composition-based stats.
 Identities = 154/245 (62%), Positives = 189/245 (77%), Gaps = 5/245 (2%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA AHTYL D WNRDKVMAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTR
Sbjct: 1   MSACAHTYLSDTWNRDKVMAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLL NALS  TL  L+KP GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R
Sbjct: 61  LSLLLNALSSKTLKDLTKPKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVD 176
             GVAV+CW+YTL+LGI RQ Y+L+K   RG C A     D ++K  PY    CKR +V+
Sbjct: 121 FGGVAVVCWLYTLLLGIARQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVN 179

Query: 177 LLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIAS 236
           L+K+ C+ +FA+TCLPEG+P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS
Sbjct: 180 LVKMSCFAVFAMTCLPEGRPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATAS 239

Query: 237 VCEFY 241
           +C+FY
Sbjct: 240 LCDFY 244
>ref|XP_804598.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN82747.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 244

 Score =  353 bits (906), Expect = 7e-96,   Method: Composition-based stats.
 Identities = 154/245 (62%), Positives = 189/245 (77%), Gaps = 5/245 (2%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA AHTYL D WNRDKVMAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTR
Sbjct: 1   MSACAHTYLSDTWNRDKVMAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           LSLL NALS  TL  L+KP GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R
Sbjct: 61  LSLLLNALSSKTLKDLAKPKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVD 176
             GVAV+CW+YTL+LGI RQ Y+L+K   RG C A     D ++K  PY    CKR +V+
Sbjct: 121 FGGVAVVCWLYTLLLGIARQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVN 179

Query: 177 LLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIAS 236
           L+K+ C+ +FA+TCLPEG+P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS
Sbjct: 180 LVKMSCFAVFAMTCLPEGRPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATAS 239

Query: 237 VCEFY 241
           +C+FY
Sbjct: 240 LCDFY 244
>ref|XP_811903.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN90052.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 226

 Score =  319 bits (817), Expect = 2e-85,   Method: Composition-based stats.
 Identities = 139/227 (61%), Positives = 174/227 (76%), Gaps = 5/227 (2%)

Query: 19  MAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSLSK 78
           MAIVQFLPMALEGP R AGC+SLA SLGNL++M D+YRAVTRLSLL NALS  TL  L+K
Sbjct: 1   MAIVQFLPMALEGPVRNAGCDSLAESLGNLSKMADSYRAVTRLSLLLNALSSKTLKDLTK 60

Query: 79  PTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLVLGIV 138
           P GD +  R++Q+SH FHIGFCLNE+TAVLAG GV    L R  GVAV+CW+YTL+LGI 
Sbjct: 61  PKGDALVWRLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTRFGGVAVVCWLYTLLLGIA 120

Query: 139 RQLYMLSKM--RGHCTAAAASGDDKRKTCPYGG--CKRVMVDLLKLVCYFLFALTCLPEG 194
           RQ Y+L+K   RG C A     D ++K  PY    CKR +V+L+K+ C+ +FA+TCLPEG
Sbjct: 121 RQAYLLAKHSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVNLVKMSCFAVFAMTCLPEG 179

Query: 195 KPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEFY 241
           +P+LL +  GPLVPLH +++A++PN LH S+TVRGLL   AS+C+FY
Sbjct: 180 RPKLLQDVCGPLVPLHELIRAIAPNKLHLSDTVRGLLAATASLCDFY 226
>ref|XP_843475.1| glycosomal membrane protein [Leishmania major strain Friedlin]
 gb|AAZ14593.1| glycosomal membrane protein [Leishmania major strain Friedlin]
          Length = 225

 Score =  300 bits (768), Expect = 7e-80,   Method: Composition-based stats.
 Identities = 129/241 (53%), Positives = 166/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSAAVFEYLGNTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSSMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P    R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDVLLDRVDQLSHFFHVCFCFFENTAVLSSHNVYPNRFVR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++K               +K  P    KR MV  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMTK---------------KKNTPEEQ-KRQMVTTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPLVPLH  ++ ++P  L  ++T+RG+LG IAS+C+F
Sbjct: 165 GCFLIFSLTCFPKGGPQLLEDVSGPLVPLHKTLQLIAPKHLELNDTIRGVLGFIASMCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>ref|XP_001469178.1| Gim5A protein; glycosomal membrane protein [Leishmania infantum]
 emb|CAM72280.1| Gim5A protein, putative; glycosomal membrane protein [Leishmania
           infantum]
          Length = 225

 Score =  296 bits (758), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 128/241 (53%), Positives = 165/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSAAVFEYLGNTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSSMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P    R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDVLLDRVDQLSHFFHVCFCFFENTAVLSSHNVYPNRFVR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++               ++K  P    KR MV  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMT---------------QKKNTPEEQ-KRQMVTTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPLVPLH  ++ ++P  L  ++T+RG LG IAS+C+F
Sbjct: 165 GCFLIFSLTCFPKGGPQLLEDVSGPLVPLHKTLQLIAPKHLGLNDTIRGALGFIASMCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>ref|XP_001568471.1| Gim5A protein, putative [Leishmania braziliensis MHOM/BR/75/M2904]
 emb|CAM43585.1| Gim5A protein, putative; glycosomal membrane protein [Leishmania
           braziliensis]
          Length = 225

 Score =  295 bits (755), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 127/241 (52%), Positives = 166/241 (68%), Gaps = 16/241 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MSA    YL +  +RDKVMAIVQFLPM L GPA  AGC SL+ SL +L+ M D YRA+TR
Sbjct: 1   MSASVFQYLANTGDRDKVMAIVQFLPMTLAGPANDAGCTSLSKSLKSLSTMADGYRAITR 60

Query: 61  LSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHR 120
           L+LL NALSKPTL +LSKP GD++  R+DQLSH FH+ FC  ENTAVL+ H V+P  L R
Sbjct: 61  LALLFNALSKPTLEALSKPKGDILLDRLDQLSHFFHVCFCFFENTAVLSSHNVYPSRLGR 120

Query: 121 LSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKL 180
           L G AV CW YTL+LG++RQ Y+++               ++K  P    KR M+  +KL
Sbjct: 121 LGGCAVTCWFYTLLLGLMRQAYVMT---------------QKKNTPEEH-KRQMITTVKL 164

Query: 181 VCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEF 240
            C+ +F+LTC P+G PQLL + SGPL+PLH  ++ ++P  L  ++T+RG LG IAS+C+F
Sbjct: 165 GCFLVFSLTCFPKGGPQLLEDVSGPLMPLHKTLQLIAPKCLELNDTIRGALGFIASLCDF 224

Query: 241 Y 241
           Y
Sbjct: 225 Y 225
>ref|XP_804601.1| hypothetical protein Tc00.1047053510669.9 [Trypanosoma cruzi strain
           CL Brener]
 gb|EAN82750.1| hypothetical protein, conserved [Trypanosoma cruzi]
          Length = 247

 Score =  267 bits (682), Expect = 6e-70,   Method: Composition-based stats.
 Identities = 61/245 (24%), Positives = 107/245 (43%), Gaps = 16/245 (6%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS 62
           A  H+YL  AW RD+V A++QF  M + G A + G  S+  S  +LAR+   Y +VTR+ 
Sbjct: 4   ALPHSYLSIAWRRDRVTAVLQFCSMVVSGVAGSVGQRSIERSAKSLARLLSEYGSVTRVC 63

Query: 63  -----LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPK- 116
                LL  + +    T  + P      +RI  ++ +F   F  +E   +LA  GV  K 
Sbjct: 64  NWLVVLLELSPAGVRRTMRASPGFFTGIARI--VTTIFLGLFLASEEVELLAAGGVLSKV 121

Query: 117 -SLHRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMV 175
              H    V +  + Y L+        + +  R      +    D +        K + +
Sbjct: 122 WRPHAARMVPIFFFYYNLLKAGTSAALLQAMQR-----ISFEATDTQSVIRKRHYKELFL 176

Query: 176 DLLKLVCYFLFALTCLPEGKPQL--LANASGPLVPLHVMVKALSPNPLHASNTVRGLLGL 233
             ++ + + ++A+T LP   P+L    N    +  ++ +  +L P  +      +GLLGL
Sbjct: 177 SFMEGIAFMVYAMTLLPSNAPRLREALNEGLWMDRVYSVFSSLCPQAVQVRPATQGLLGL 236

Query: 234 IASVC 238
           +A+  
Sbjct: 237 LATAP 241
>ref|XP_001568470.1| hypothetical protein LbrM34_V2.3670 [Leishmania braziliensis
           MHOM/BR/75/M2904]
 emb|CAM43584.1| hypothetical protein, conserved [Leishmania braziliensis]
          Length = 253

 Score =  257 bits (657), Expect = 5e-67,   Method: Composition-based stats.
 Identities = 72/250 (28%), Positives = 111/250 (44%), Gaps = 24/250 (9%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS 62
           A  + Y+ +  NRD+VM++VQF  MAL GPA  AGC  L+     +  +   YR +TR S
Sbjct: 11  ATFNDYIGNVSNRDRVMSVVQFSAMALTGPAAAAGCSKLSAHFNTIHHIAAHYRTITRFS 70

Query: 63  ---LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGH-----GVF 114
              ++A AL+   +T       + +      +S  F   F + E   VLA        V 
Sbjct: 71  QWLVVAPALTYSGITGALNSHPNPLVGICKTISTAFFTVFLIGEEL-VLASKSNMLDPVL 129

Query: 115 PKSLHRLSGVAVLCWMYTLVLGIVRQL--YMLSKMRGHCTAAAASGDDKRKTCPYGGCKR 172
            K L+R+  V  L W       I R +  Y+L K   +        + K K         
Sbjct: 130 GKHLNRIRFV-FLFWS-----NIARLIMNYLLLKSSSYDAVKDTQNEKKAKDHRRKVLSV 183

Query: 173 VMVDLLKLVCYFLFALTCLPEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGL 230
               L  + CY L   +  P G P+ L+ A  SG +V    ++ +L+P  +   +T +G+
Sbjct: 184 ADGVLQSMFCYTLLK-SSAPAG-PKYLSAALQSGNVVD---VITSLAPPLIAVPSTPQGI 238

Query: 231 LGLIASVCEF 240
           +GL+ASV  F
Sbjct: 239 IGLVASVPGF 248
>ref|XP_811904.1| hypothetical protein Tc00.1047053507009.20 [Trypanosoma cruzi
           strain CL Brener]
 gb|EAN90053.1| hypothetical protein, conserved [Trypanosoma cruzi]
          Length = 247

 Score =  256 bits (656), Expect = 7e-67,   Method: Composition-based stats.
 Identities = 60/245 (24%), Positives = 106/245 (43%), Gaps = 16/245 (6%)

Query: 3   AQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS 62
           A  H+ L  AW RD+V A++QF  M + G A + G  S+  S  +LAR+   Y +VTR+ 
Sbjct: 4   ALPHSCLSIAWRRDRVPAVLQFCSMVVSGVAGSVGHRSIERSAKSLARLLSEYGSVTRVC 63

Query: 63  -----LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPK- 116
                LL  + +    T  + P      +RI  ++ +F   F  +E   +LA  GV  K 
Sbjct: 64  NWLVVLLELSPAGVRRTMRTSPGFFTGIARI--VTTIFLGLFLASEEVELLAAGGVLSKL 121

Query: 117 -SLHRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMV 175
              H    V +  + Y L+        + +  R      +    D +        K + +
Sbjct: 122 WRPHAARMVPIFFFYYNLLKAATSAALLQAMQR-----ISFEATDTQSVIRKRHYKELFL 176

Query: 176 DLLKLVCYFLFALTCLPEGKPQL--LANASGPLVPLHVMVKALSPNPLHASNTVRGLLGL 233
             ++ + + ++A+T LP   P+L    N    +  ++ +  +L P  +      +GLLGL
Sbjct: 177 SFMEGIAFMVYAMTLLPSNAPRLREALNEGFWMDRVYSVFSSLCPQAVQVRPATQGLLGL 236

Query: 234 IASVC 238
           +A+  
Sbjct: 237 LATAP 241
>ref|XP_827421.1| hypothetical protein Tb09.211.2750 [Trypanosoma brucei TREU927]
 gb|EAN77091.1| hypothetical protein, conserved [Trypanosoma brucei]
          Length = 246

 Score =  248 bits (635), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 50/250 (20%), Positives = 94/250 (37%), Gaps = 16/250 (6%)

Query: 1   MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTR 60
           MS+          +  +++A+ QF  +   G A +     +A S   LA++   Y  ++R
Sbjct: 1   MSSLPPDKTLFGSHSQRLVAVAQFCSLVSAGVAGSKHYTLVARSACALAKVLANYLCLSR 60

Query: 61  LS-----LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFP 115
           L      L   + S       S P+      R+  L+ L  + F + +  A+LA  GV  
Sbjct: 61  LKGSYLLLREVSPSSVRRRLHSSPSWFTGVMRV--LTMLAMLLFRITDKIALLANEGVLS 118

Query: 116 KS--LHRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRV 173
            +   +    +  L +   L+  +     + +         +    D R         + 
Sbjct: 119 NNICFYTSRLIPSLLFYCNLMQTMTSAALLKA-----VRPISFEATDTRNVFRKRYYLQG 173

Query: 174 MVDLLKLVCYFLFALTCLPEGKPQLL--ANASGPLVPLHVMVKALSPNPLHASNTVRGLL 231
           ++  L+ V    +A+T  P G P L    +    L     +  +  P  L  S T +GL+
Sbjct: 174 VLSFLEGVGLMTYAMTLFPRGVPPLAMTLHEKHLLTHWLAVAASSFPPALSVSTTTQGLI 233

Query: 232 GLIASVCEFY 241
           GL A++  F+
Sbjct: 234 GLAATLPSFF 243
>ref|XP_001469177.1| hypothetical protein [Leishmania infantum]
 emb|CAM72279.1| hypothetical protein, conserved [Leishmania infantum]
          Length = 253

 Score =  236 bits (602), Expect = 1e-60,   Method: Composition-based stats.
 Identities = 72/249 (28%), Positives = 109/249 (43%), Gaps = 24/249 (9%)

Query: 4   QAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS- 62
             + Y+ +A NRD+VM++VQF  MAL  PA  AGC  L+     +      YR VTR S 
Sbjct: 12  AFNDYVGNASNRDRVMSVVQFGAMALVAPAAAAGCPELSAHFDTILHGAAHYRTVTRFSQ 71

Query: 63  --LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGH-----GVFP 115
             ++A AL+   + S+     + +      +S  F   F + E   VLA        VF 
Sbjct: 72  WLVVAPALTPSGIKSVIASHPNPLVGICKTISTAFFTVFLIGEEL-VLASKCNMLDPVFG 130

Query: 116 KSLHRLSGVAVLCWMYTLVLGIVRQL--YMLSKMRGHCTAAAASGDDKRKTCPYGGCKRV 173
           +  +R+  V  L W       I R +  Y+L K   +     +  ++K K          
Sbjct: 131 RHFNRIRFV-FLFWS-----NIARLVMNYLLLKSSKYDAVKDSQNEEKAKDHRRKVLNVA 184

Query: 174 MVDLLKLVCYFLFALTCLPEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGLL 231
              L  + CY L   +  P G P+ L+ A  SG  V +   + +L+P      +T +G+L
Sbjct: 185 DGVLQSMFCYTLLK-SSAPAG-PKYLSAALRSGKAVDI---ITSLAPPLFVVPSTPQGML 239

Query: 232 GLIASVCEF 240
           GL ASV  F
Sbjct: 240 GLAASVPGF 248
>ref|XP_843474.1| hypothetical protein, conserved [Leishmania major strain Friedlin]
 gb|AAZ14592.1| hypothetical protein, conserved [Leishmania major strain Friedlin]
          Length = 253

 Score =  227 bits (579), Expect = 6e-58,   Method: Composition-based stats.
 Identities = 74/249 (29%), Positives = 109/249 (43%), Gaps = 24/249 (9%)

Query: 4   QAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLS- 62
             + Y+ +A NRD+VM++VQF  MAL  PA  AGC  L+  L  +      YR VTR S 
Sbjct: 12  AFNNYVGNASNRDRVMSVVQFGAMALAAPAAAAGCPELSAHLSTILHGAAHYRTVTRFSQ 71

Query: 63  --LLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGH-----GVFP 115
             ++A AL+   + S      +++      +S  F   F + E   VLA        V  
Sbjct: 72  WLVVAPALTPSGIKSAIASHPNLLVGICKTISTAFFTVFLIGEEL-VLASKCNMLDPVLG 130

Query: 116 KSLHRLSGVAVLCWMYTLVLGIVRQL--YMLSKMRGHCTAAAASGDDKRKTCPYGGCKRV 173
           K  +R+  V  L W       I R +  Y+L K   +        ++K K          
Sbjct: 131 KRFNRIRFV-FLFWS-----NIARLVMSYLLLKSSKYDAVKDNQNEEKAKDHRRKVLGVA 184

Query: 174 MVDLLKLVCYFLFALTCLPEGKPQLLANA--SGPLVPLHVMVKALSPNPLHASNTVRGLL 231
              L  + CY L   +  P G P+ L+ A  SG  V +   + +L+P  L   +T +G+L
Sbjct: 185 DGVLQSMFCYTLLK-SSAPAG-PKYLSAALRSGKAVDI---ITSLAPPLLVVPSTPQGML 239

Query: 232 GLIASVCEF 240
           GL ASV  F
Sbjct: 240 GLAASVPGF 248
>ref|XP_804602.1| Gim5A protein, putative [Trypanosoma cruzi strain CL Brener]
 gb|EAN82751.1| Gim5A protein, putative [Trypanosoma cruzi]
          Length = 161

 Score =  226 bits (576), Expect = 2e-57,   Method: Composition-based stats.
 Identities = 90/159 (56%), Positives = 118/159 (74%), Gaps = 5/159 (3%)

Query: 87  RIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLVLGIVRQLYMLSK 146
           R++Q+SH FHIGFCLNE+TAVLAG GV    L R  GVAV+CW+YTL+LGI RQ Y+L+K
Sbjct: 4   RLEQVSHAFHIGFCLNEHTAVLAGRGVLNSGLTRFGGVAVVCWLYTLLLGIARQAYLLAK 63

Query: 147 M--RGHCTAAAASGDDKRKTCPYGG--CKRVMVDLLKLVCYFLFALTCLPEGKPQLLANA 202
              RG C A     D ++K  PY    CKR +V+L+K+ C+ +FA TCLPEG+P+LL + 
Sbjct: 64  HSPRGSCKALLPE-DAEKKVVPYTHEECKRAVVNLVKMSCFAVFAKTCLPEGRPKLLQDV 122

Query: 203 SGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEFY 241
            GPLVPLH +++A++PN LH S+TVRGLL   AS+C+FY
Sbjct: 123 CGPLVPLHELIRAIAPNKLHLSDTVRGLLAATASLCDFY 161
>gb|ACO51908.1| Peroxisomal membrane protein 11C [Rana catesbeiana]
          Length = 235

 Score = 38.2 bits (88), Expect = 0.48,   Method: Composition-based stats.
 Identities = 31/138 (22%), Positives = 52/138 (37%), Gaps = 2/138 (1%)

Query: 15  RDKVMAIVQFLPMALEGPARTAGCES--LALSLGNLARMGDAYRAVTRLSLLANALSKPT 72
           RD++M  + +    L G       +      S   +A      R V RL    + L+   
Sbjct: 18  RDRLMRTLCYSCQLLGGVITQKHGDKQQYGKSFLIIASQLSHCRTVLRLFDDLSMLAYSF 77

Query: 73  LTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYT 132
              L K   D +   I  + ++F   +   E+ A  A  GV           +   W  +
Sbjct: 78  QYGLGKKEEDRLIRWISVIGNIFDQLYYPCEHVAWAADAGVIRTKSDIWWTASTALWGLS 137

Query: 133 LVLGIVRQLYMLSKMRGH 150
           L++GI+R L +L K+R  
Sbjct: 138 LLVGIIRSLRILLKLRRS 155
>ref|XP_394365.2| PREDICTED: similar to CG8315-PA isoform 1 [Apis mellifera]
 ref|XP_623134.1| PREDICTED: similar to CG8315-PA isoform 2 [Apis mellifera]
          Length = 232

 Score = 38.2 bits (88), Expect = 0.54,   Method: Composition-based stats.
 Identities = 24/133 (18%), Positives = 59/133 (44%), Gaps = 4/133 (3%)

Query: 15  RDKVMAIVQFLPMALEGPARTAGCESLALS-LGNLARMGDAYRAVTRLSLLANALSKPTL 73
           RD+++ ++Q+   A    A+ +     +   L +L     ++R + RL    ++L    L
Sbjct: 14  RDRIIRLLQYGSRAYWYYAQKSHSTQNSAEILRSLEYTFSSFRKLLRLGRCLDSL-YSAL 72

Query: 74  TSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTL 133
             +  P  ++       LS + +  F L ++   +   G+   ++ + S +A   W+  +
Sbjct: 73  KMMKYP--EVTIRVTLTLSKIANALFLLADHIIWIGRVGLLRVNIKKWSKIANKYWLMNI 130

Query: 134 VLGIVRQLYMLSK 146
           ++ + R +Y + K
Sbjct: 131 IMNLTRDIYEIIK 143
>gb|EDN36632.1| predicted protein [Francisella tularensis subsp. novicida
          GA99-3549]
          Length = 246

 Score = 36.3 bits (83), Expect = 1.8,   Method: Composition-based stats.
 Identities = 16/55 (29%), Positives = 28/55 (50%), Gaps = 6/55 (10%)

Query: 35 TAGCESLALSLGNLARMGDAY----RAVTRLSLLANALSKPTLTSLSKPTGDMVA 85
             C+ L  SL NL R+   Y    R +  + +L +++S PT+  +SK   D++ 
Sbjct: 14 NKFCDKL--SLNNLLRILANYNIQARNIKFIPVLFSSVSTPTILGISKSHNDILV 66
>ref|NP_784281.1| fucose transport protein [Lactobacillus plantarum WCFS1]
 emb|CAD63122.1| fucose transport protein [Lactobacillus plantarum WCFS1]
          Length = 454

 Score = 36.3 bits (83), Expect = 2.0,   Method: Composition-based stats.
 Identities = 20/78 (25%), Positives = 31/78 (39%), Gaps = 5/78 (6%)

Query: 124 VAVLCWMYTLVLGIVRQLYMLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKLVCY 183
           V +L   Y +          ++KM G    A      ++   PY     V+     LV  
Sbjct: 169 VGILLGKYLIFNDGASLATTMAKMHGAARLAYGQRMLQQTLLPYKYLIVVL-----LVAI 223

Query: 184 FLFALTCLPEGKPQLLAN 201
           F+F LT  P GKP+  ++
Sbjct: 224 FIFVLTQFPSGKPKQRSD 241
>ref|YP_001365955.1| integral membrane sensor hybrid histidine kinase [Shewanella
           baltica OS185]
 gb|ABS07892.1| integral membrane sensor hybrid histidine kinase [Shewanella
           baltica OS185]
          Length = 1146

 Score = 35.5 bits (81), Expect = 3.6,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 22/55 (40%), Gaps = 5/55 (9%)

Query: 89  DQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLS-----GVAVLCWMYTLVLGIV 138
           D LSHL  + F      A     G++ K  +R       GV    W Y ++ G+ 
Sbjct: 401 DSLSHLGMLSFGAFAQLAPALVGGLYWKHGNRAGVFLGLGVGFTLWFYIMLQGMT 455
>ref|YP_001050131.1| integral membrane sensor hybrid histidine kinase [Shewanella
           baltica OS155]
 gb|ABN61262.1| integral membrane sensor hybrid histidine kinase [Shewanella
           baltica OS155]
          Length = 1146

 Score = 35.5 bits (81), Expect = 3.7,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 22/55 (40%), Gaps = 5/55 (9%)

Query: 89  DQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLS-----GVAVLCWMYTLVLGIV 138
           D LSHL  + F      A     G++ K  +R       GV    W Y ++ G+ 
Sbjct: 401 DSLSHLGMLSFGAFAQLAPALVGGLYWKHGNRAGVFLGLGVGFTLWFYIMLQGMT 455
>ref|YP_001554223.1| integral membrane sensor hybrid histidine kinase [Shewanella
           baltica OS195]
 gb|ABX48963.1| integral membrane sensor hybrid histidine kinase [Shewanella
           baltica OS195]
          Length = 1146

 Score = 35.5 bits (81), Expect = 3.7,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 22/55 (40%), Gaps = 5/55 (9%)

Query: 89  DQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLS-----GVAVLCWMYTLVLGIV 138
           D LSHL  + F      A     G++ K  +R       GV    W Y ++ G+ 
Sbjct: 401 DSLSHLGMLSFGAFAQLAPALVGGLYWKHGNRAGVFLGLGVGFTLWFYIMLQGMT 455
>ref|XP_001838198.1| hypothetical protein CC1G_07939 [Coprinopsis cinerea okayama7#130]
 gb|EAU83566.1| hypothetical protein CC1G_07939 [Coprinopsis cinerea okayama7#130]
          Length = 1786

 Score = 35.1 bits (80), Expect = 3.8,   Method: Composition-based stats.
 Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 5/98 (5%)

Query: 53  DAYRAVTRLSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHG 112
           DAY     L LLAN+     L   S      +   ++ +   +H  F  +E   +L  H 
Sbjct: 145 DAYSVFEDLCLLANSEKPRFLKLESLHKTFAL-ELVESVLTNYHGLFRKHEEMILLLRHH 203

Query: 113 VFPKSLHRLSGVAVLCWMYTLVLGIVRQLYMLSKMRGH 150
           + P  L  +S   +      L+L   R +++L K   H
Sbjct: 204 LCPLLLKTVSERPIF----PLILRCTRVIFLLLKQFSH 237
>ref|ZP_00834525.1| hypothetical protein YintA_01001073 [Yersinia intermedia ATCC
           29909]
          Length = 310

 Score = 35.1 bits (80), Expect = 3.9,   Method: Composition-based stats.
 Identities = 20/89 (22%), Positives = 33/89 (37%), Gaps = 7/89 (7%)

Query: 9   LCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLANAL 68
            C    R+  M I  F+    + P   AG    A SL  L    ++ +++    LL  + 
Sbjct: 219 TCINSKRENEMYIYHFVSTTRDTPTDPAG--KFAQSLEKLMDALNSGKSM----LLETSA 272

Query: 69  SKPTLTSLSKPTGDMVASRIDQLSHLFHI 97
            K        P+       + +LS + HI
Sbjct: 273 IKEFRRLH-NPSHFPGLGIVKKLSMIHHI 300
>dbj|BAC26361.1| unnamed protein product [Mus musculus]
          Length = 650

 Score = 35.1 bits (80), Expect = 4.2,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 283 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 323
>gb|AAN77886.1| ribosomal protein S4 [Myxine glutinosa]
          Length = 238

 Score = 35.1 bits (80), Expect = 4.4,   Method: Composition-based stats.
 Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 3/88 (3%)

Query: 13 WNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSL-LANALSKP 71
          W  DK+  +  F P    GP R   C SL + L N  R    Y  V ++ +     +   
Sbjct: 8  WMLDKLTGV--FAPRPSTGPHRLRECLSLIIFLRNRLRYALTYDEVKKICMQRLIKIDGK 65

Query: 72 TLTSLSKPTGDMVASRIDQLSHLFHIGF 99
            T ++ P G M    ID+ S  F + +
Sbjct: 66 VRTDITYPAGFMDVITIDKTSENFRLIY 93
>ref|ZP_01707330.1| periplasmic sensor hybrid histidine kinase [Shewanella putrefaciens
           200]
 gb|EAY52303.1| periplasmic sensor hybrid histidine kinase [Shewanella putrefaciens
           200]
          Length = 1190

 Score = 35.1 bits (80), Expect = 4.5,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 89  DQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLS-----GVAVLCWMYTLVLGIV 138
           D LSHL  + F      A     G++ K  +R       GV  + W Y ++ G+ 
Sbjct: 446 DSLSHLGMLSFGAFAQLAPALVGGLYWKHGNRAGVFLGLGVGFVLWFYLMLQGMA 500
>gb|EEH53081.1| predicted protein [Micromonas pusilla CCMP1545]
          Length = 233

 Score = 35.1 bits (80), Expect = 4.6,   Method: Composition-based stats.
 Identities = 30/151 (19%), Positives = 53/151 (35%), Gaps = 10/151 (6%)

Query: 15  RDKVMAIVQFLPM-ALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTL 73
           +DK +A++Q++ M A  G A TA   ++  SLG   +    +R    +  L   L+  TL
Sbjct: 25  KDKAIALLQYVAMFASGGEAGTA--LAIQKSLGAARK---PFRVFKPIETLMPLLTGATL 79

Query: 74  TSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTL 133
               +  G  +A  +  +  L    +   ++       GV            V  W + L
Sbjct: 80  RGGKRRPGQDLARALSLVKTLGMTFYFAADHVVWAGAAGVLSDKSLAQRAQKVSYWSWCL 139

Query: 134 VLGIVRQLYMLSKMRGHCTAAAASGDDKRKT 164
                    + +  R    A  A     +K 
Sbjct: 140 ----ASLAGLATATRELTDALDAMTAATKKD 166
>gb|EAW54524.1| KIAA0913, isoform CRA_d [Homo sapiens]
          Length = 1579

 Score = 35.1 bits (80), Expect = 4.7,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 404 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 444
>ref|NP_611071.1| CG8315 CG8315-PA [Drosophila melanogaster]
 gb|AAF58084.1| CG8315-PA [Drosophila melanogaster]
 gb|AAL48984.1| RE39562p [Drosophila melanogaster]
          Length = 241

 Score = 35.1 bits (80), Expect = 4.9,   Method: Composition-based stats.
 Identities = 45/249 (18%), Positives = 82/249 (32%), Gaps = 49/249 (19%)

Query: 12  AWNRDKVMAIVQFLPMALEGPARTAGC-ESLALSLGNLARMGDAYRAVTRLSLLANALSK 70
           A  RDK+  ++Q+   A+     +A    +L  +   +  +   +R + R     +    
Sbjct: 11  AGGRDKIARLIQYASRAMWDSLESANSNPALVDNFKTVEYILSTFRKLLRFGKCVDVFYG 70

Query: 71  PTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWM 130
              T       D+       LS L    F   ++   LA  G+   +  R S +A   W+
Sbjct: 71  ALKTIH---HPDLNIRVTLTLSKLSQSLFLFADHFLWLARTGLTAVNAKRWSNIANKYWL 127

Query: 131 YTLVLGIVRQLY----MLSKMRGHCT--------------AAAASGDDKRKTCPYGGCKR 172
           +++++ + R  Y    +L   R                           +      G K 
Sbjct: 128 FSIIMNLCRDFYEILRVLDLHRSGSKSGISRCRIPASINSPEDFKRLALQSYVLMQGHKD 187

Query: 173 VMVDLLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLG 232
           ++VD +K  C F   LT L                       +L+P  +       GLLG
Sbjct: 188 IVVDTVKNACDFFIPLTAL--------------------GYTSLTPRTI-------GLLG 220

Query: 233 LIASVCEFY 241
            I+S+   +
Sbjct: 221 AISSLAGLW 229
>dbj|BAA74936.1| KIAA0913 protein [Homo sapiens]
          Length = 1301

 Score = 35.1 bits (80), Expect = 4.9,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 126 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 166
>ref|YP_963051.1| integral membrane sensor hybrid histidine kinase [Shewanella sp.
           W3-18-1]
 ref|YP_001183868.1| integral membrane sensor hybrid histidine kinase [Shewanella
           putrefaciens CN-32]
 gb|ABM24497.1| integral membrane sensor hybrid histidine kinase [Shewanella sp.
           W3-18-1]
 gb|ABP76069.1| integral membrane sensor hybrid histidine kinase [Shewanella
           putrefaciens CN-32]
          Length = 1145

 Score = 35.1 bits (80), Expect = 4.9,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 89  DQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLS-----GVAVLCWMYTLVLGIV 138
           D LSHL  + F      A     G++ K  +R       GV  + W Y ++ G+ 
Sbjct: 401 DSLSHLGMLSFGAFAQLAPALVGGLYWKHGNRAGVFLGLGVGFVLWFYLMLQGMA 455
>ref|XP_001365228.1| PREDICTED: hypothetical protein [Monodelphis domestica]
          Length = 1827

 Score = 34.7 bits (79), Expect = 5.5,   Method: Composition-based stats.
 Identities = 11/43 (25%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ++S      L
Sbjct: 403 RSNGQTEVAAHAC--ASMCDEMVTLWRLAVLDPSISPQRRRDL 443
>ref|XP_507850.2| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]
          Length = 1834

 Score = 34.7 bits (79), Expect = 6.1,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 404 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 444
>ref|NP_055852.2| hypothetical protein LOC23053 [Homo sapiens]
 gb|AAI56551.1| KIAA0913 [synthetic construct]
          Length = 1842

 Score = 34.7 bits (79), Expect = 6.1,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 404 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 444
>sp|A7E2V4|K0913_HUMAN Zinc finger SWIM domain-containing protein KIAA0913
 gb|AAI51207.1| KIAA0913 protein [Homo sapiens]
          Length = 1837

 Score = 34.7 bits (79), Expect = 6.1,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 404 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 444
>ref|NP_082272.1| hypothetical protein LOC268721 [Mus musculus]
 sp|Q3UHH1|K0913_MOUSE Zinc finger SWIM domain-containing protein KIAA0913
 dbj|BAE27886.1| unnamed protein product [Mus musculus]
 gb|AAI51047.1| RIKEN cDNA 2310021P13 gene [Mus musculus]
 gb|AAI51057.1| RIKEN cDNA 2310021P13 gene [Mus musculus]
          Length = 1832

 Score = 34.7 bits (79), Expect = 6.2,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 404 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 444
>ref|XP_536393.2| PREDICTED: similar to CG32542-PA isoform 2 [Canis familiaris]
          Length = 1800

 Score = 34.7 bits (79), Expect = 6.2,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 404 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 444
>gb|EDL01494.1| mCG121327 [Mus musculus]
          Length = 1852

 Score = 34.7 bits (79), Expect = 6.3,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 419 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 459
>ref|XP_001099765.1| PREDICTED: similar to CG32542-PA isoform 1 [Macaca mulatta]
          Length = 1834

 Score = 34.7 bits (79), Expect = 6.3,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 404 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 444
>ref|XP_001605353.1| PREDICTED: similar to ATP-binding cassette sub-family A member 3,
            putative [Nasonia vitripennis]
          Length = 1660

 Score = 34.7 bits (79), Expect = 6.3,   Method: Composition-based stats.
 Identities = 19/110 (17%), Positives = 39/110 (35%), Gaps = 11/110 (10%)

Query: 88   IDQLSHLFHIGFCLNENTAVLAGHGV-----FPKSLHRLSGVAVLCWMYTLVLGIVRQLY 142
            ++ ++      F      A+ A H +     + K L R++GV  + +   ++   +    
Sbjct: 1016 VNAITTAIIFCFLFFPTIALFALHPLRETSTYVKQLQRMAGVPFIEYWGNMMFFDMGS-- 1073

Query: 143  MLSKMRGHCTAAAASGDDKRKTCPYGGCKRVMVDLLKLVCYFLFALTCLP 192
                +            D+         +  +V  +  +CY LFAL  LP
Sbjct: 1074 --LVLLLALLIGGFVAMDEILGFRIFDLREPVV--ISAICYMLFALNTLP 1119
>dbj|BAG10398.1| KIAA0913 protein [synthetic construct]
          Length = 1796

 Score = 34.7 bits (79), Expect = 6.3,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 404 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 444
>ref|NP_597415.1| SERINE PALMITOYL TRANSFERASE SUBUNIT 2 [Encephalitozoon cuniculi
           GB-M1]
 emb|CAD26592.1| SERINE PALMITOYL TRANSFERASE SUBUNIT 2 [Encephalitozoon cuniculi
           GB-M1]
          Length = 475

 Score = 34.4 bits (78), Expect = 6.5,   Method: Composition-based stats.
 Identities = 15/44 (34%), Positives = 22/44 (50%), Gaps = 4/44 (9%)

Query: 6   HTYLCDAWNR----DKVMAIVQFLPMALEGPARTAGCESLALSL 45
           + YL  + N+    +KV+  V   P+ L  PAR  GC  +A  L
Sbjct: 113 YNYLGFSSNKGPVVEKVVKAVYRYPLVLAAPAREVGCYDIAREL 156
>ref|XP_341280.2| PREDICTED: similar to CG32542-PA [Rattus norvegicus]
 ref|XP_001057186.1| PREDICTED: similar to CG32542-PA [Rattus norvegicus]
          Length = 1831

 Score = 34.4 bits (78), Expect = 6.6,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 404 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 444
>gb|AAH85161.1| 2310021P13Rik protein [Mus musculus]
          Length = 1735

 Score = 34.4 bits (78), Expect = 6.8,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 341 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 381
>ref|XP_001146127.1| PREDICTED: hypothetical protein isoform 1 [Pan troglodytes]
          Length = 1535

 Score = 34.4 bits (78), Expect = 6.8,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34 RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
          R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 47 RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 87
>gb|EDL86245.1| similar to KIAA0913 protein (predicted) [Rattus norvegicus]
          Length = 1517

 Score = 34.4 bits (78), Expect = 7.5,   Method: Composition-based stats.
 Identities = 13/43 (30%), Positives = 18/43 (41%), Gaps = 2/43 (4%)

Query: 34  RTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSL 76
           R+ G   +A      A M D    + RL++L  ALS      L
Sbjct: 86  RSNGQSEVAAHAC--ASMCDEMVTLWRLAVLDPALSPQRRREL 126
>ref|ZP_01843674.1| integral membrane sensor hybrid histidine kinase [Shewanella
           baltica OS223]
 gb|EDK48632.1| integral membrane sensor hybrid histidine kinase [Shewanella
           baltica OS223]
          Length = 1146

 Score = 34.0 bits (77), Expect = 9.4,   Method: Composition-based stats.
 Identities = 15/55 (27%), Positives = 22/55 (40%), Gaps = 5/55 (9%)

Query: 89  DQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLS-----GVAVLCWMYTLVLGIV 138
           D LSHL  + F      A     G++ K  +R       GV    W Y ++ G+ 
Sbjct: 401 DSLSHLGMLSFGAFAQLAPALVGGLYWKHGNRAGVFLGLGVGFSLWFYIMLQGMT 455
  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF excluding environmental samples
  from WGS projects
    Posted date:  May 23, 2008  5:56 PM
  Number of letters in database: 883,778,997
  Number of sequences in database:  2,617,685
  
  Database: /host/Blast/data/nr_perl/nr.01
    Posted date:  May 23, 2008  5:54 PM
  Number of letters in database: 976,759,346
  Number of sequences in database:  2,761,413
  
  Database: /host/Blast/data/nr_perl/nr.02
    Posted date:  May 23, 2008  5:48 PM
  Number of letters in database: 374,670,760
  Number of sequences in database:  1,165,270
  
  Database: /host/Blast/data/nr_perl/nr.03
    Posted date:  Apr 28, 2009  5:40 PM
  Number of letters in database: 114,943,120
  Number of sequences in database:  354,819
  
Lambda     K      H
   0.315    0.165    0.450 

Lambda     K      H
   0.267   0.0503    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,788,866,017
Number of Sequences: 6899187
Number of extensions: 180199008
Number of successful extensions: 530844
Number of sequences better than 10.0: 100
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 321
Number of HSP's that attempted gapping in prelim test: 530659
Number of HSP's gapped (non-prelim): 391
length of query: 241
length of database: 2,350,152,223
effective HSP length: 130
effective length of query: 111
effective length of database: 1,453,257,913
effective search space: 161311628343
effective search space used: 161311628343
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (20.8 bits)
S2: 77 (34.0 bits)