BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= EAN78432.1__[Trypanosoma_brucei]
(492 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_823260.1| trypanothione reductase [Trypanosoma bruce... 1008 0.0
sp|P39051|TYTR_TRYBB Trypanothione reductase (TR) (N(1),N(8... 992 0.0
sp|P13110|TYTR_TRYCO Trypanothione reductase (TR) (N(1),N(8... 888 0.0
sp|P28593|TYTR_TRYCR Trypanothione reductase (TR) (N(1),N(8... 856 0.0
pdb|1NDA|A Chain A, The Structure Of Trypanosoma Cruzi Tryp... 856 0.0
ref|XP_805296.1| trypanothione reductase [Trypanosoma cruzi... 852 0.0
pdb|1GXF|A Chain A, Crystal Structure Of Trypanosoma Cruzi ... 852 0.0
pdb|1BZL|A Chain A, Crystal Structure Of Trypanosoma Cruzi ... 851 0.0
pdb|1AOG|A Chain A, Trypanosoma Cruzi Trypanothione Reducta... 848 0.0
gb|AAB59211.1| trypanothione reductase [Trypanosoma cruzi] 788 0.0
gb|AAK71224.1|AF359006_1 trypanothione reductase [Trypanoso... 754 0.0
gb|AAK71210.1|AF358992_1 trypanothione reductase [Trypanoso... 747 0.0
gb|AAK71204.1|AF358986_1 trypanothione reductase [Trypanoso... 747 0.0
gb|AAK71206.1|AF358988_1 trypanothione reductase [Trypanoso... 746 0.0
gb|AAK71199.1|AF358981_1 trypanothione reductase [Trypanoso... 746 0.0
gb|AAK71187.1|AF358969_1 trypanothione reductase [Trypanoso... 745 0.0
gb|AAX40393.1| trypanothione reductase [Trypanosoma cruzi] ... 745 0.0
gb|AAX40409.1| trypanothione reductase [Trypanosoma cruzi] ... 745 0.0
gb|AAX40408.1| trypanothione reductase [Trypanosoma cruzi] 745 0.0
gb|AAK71208.1|AF358990_1 trypanothione reductase [Trypanoso... 745 0.0
gb|AAX40399.1| trypanothione reductase [Trypanosoma cruzi] ... 744 0.0
gb|AAK71226.1|AF359008_1 trypanothione reductase [Trypanoso... 743 0.0
gb|AAK71189.1|AF358971_1 trypanothione reductase [Trypanoso... 743 0.0
gb|AAX40400.1| trypanothione reductase [Trypanosoma cruzi] 742 0.0
gb|AAX40410.1| trypanothione reductase [Trypanosoma cruzi] 742 0.0
gb|AAX40402.1| trypanothione reductase [Trypanosoma cruzi] 742 0.0
gb|AAX40392.1| trypanothione reductase [Trypanosoma cruzi] 741 0.0
gb|AAX40398.1| trypanothione reductase [Trypanosoma cruzi] 740 0.0
gb|AAX40406.1| trypanothione reductase [Trypanosoma cruzi] 739 0.0
gb|AAX40407.1| trypanothione reductase [Trypanosoma cruzi] 738 0.0
pdb|1TYP|A Chain A, Substrate Interactions Between Trypanot... 732 0.0
sp|P39040|TYTR_CRIFA Trypanothione reductase (TR) (N(1),N(8... 731 0.0
pdb|1FEA|A Chain A, Unliganded Crithidia Fasciculata Trypan... 728 0.0
pdb|1TYT|A Chain A, Crystal And Molecular Structure Of Crit... 727 0.0
gb|AAA30322.1| trypanothione reductase 725 0.0
gb|AAA30323.1| trypanothione reductase 724 0.0
pdb|2TPR|A Chain A, X-Ray Structure Of Trypanothione Reduct... 724 0.0
ref|XP_001561849.1| trypanothione reductase [Leishmania bra... 708 0.0
ref|XP_001462998.1| trypanothione reductase [Leishmania inf... 694 0.0
ref|XP_001687512.1| trypanothione reductase [Leishmania maj... 689 0.0
gb|ABQ57410.1| trypanothione reductase [Leishmania amazonen... 679 0.0
sp|P39050|TYTR_LEIDO Trypanothione reductase (TR) (N(1),N(8... 677 0.0
ref|XP_803005.1| trypanothione reductase, putative [Trypano... 668 0.0
gb|ABF74601.1| trypanothione reductase [Leishmania amazonen... 650 0.0
emb|CAC94295.1| trypanothione reductase [Leishmania donovan... 577 e-163
gb|AAA30321.1| trypanothione reductase 559 e-157
gb|AAM28598.1| putative trypanothione reductase [Entamoeba ... 445 e-123
ref|YP_001187841.1| glutathione reductase [Pseudomonas mend... 362 3e-98
ref|ZP_01910047.1| glutathione-disulfide reductase [Plesioc... 361 1e-97
ref|ZP_02188264.1| glutathione-disulfide reductase [alpha p... 358 8e-97
ref|YP_001348623.1| glutathione reductase [Pseudomonas aeru... 354 1e-95
emb|CAO22640.1| unnamed protein product [Vitis vinifera] 352 4e-95
ref|YP_260503.1| glutathione reductase [Pseudomonas fluores... 352 5e-95
gb|AAB70837.1| glutathione reductase (NADPH) [Vitis vinifera] 351 1e-94
emb|CAN66042.1| hypothetical protein [Vitis vinifera] 350 1e-94
ref|YP_791214.1| glutathione reductase [Pseudomonas aerugin... 350 1e-94
sp|P80461|GSHRP_TOBAC Glutathione reductase, chloroplast pr... 350 1e-94
ref|YP_001418110.1| glutathione-disulfide reductase [Xantho... 349 2e-94
dbj|BAF80308.1| chloroplastic glutathione reductase [Hordeu... 349 3e-94
ref|YP_317837.1| glutathione reductase [Nitrobacter winogra... 348 4e-94
ref|ZP_01166092.1| glutathione reductase [Oceanospirillum s... 348 5e-94
ref|NP_250715.1| glutathione reductase [Pseudomonas aerugin... 348 6e-94
ref|NP_001049057.1| Os03g0163300 [Oryza sativa (japonica cu... 347 1e-93
ref|YP_576764.1| Glutathione reductase [Nitrobacter hamburg... 347 1e-93
ref|XP_001754283.1| predicted protein [Physcomitrella paten... 347 1e-93
ref|NP_794013.1| glutathione reductase [Pseudomonas syringa... 347 2e-93
ref|NP_102306.1| glutathione reductase [Mesorhizobium loti ... 346 2e-93
gb|AAK27157.1|AF349449_1 glutathione reductase [Brassica ju... 345 5e-93
ref|ZP_02166732.1| glutathione reductase [Hoeflea phototrop... 345 6e-93
ref|YP_001352656.1| glutathione reductase (NADPH) [Janthino... 345 7e-93
ref|YP_001631533.1| probable glutathione reductase [Bordete... 345 7e-93
ref|NP_883660.1| glutathione reductase [Bordetella parapert... 345 7e-93
gb|AAF26175.1|AF105199_1 glutathione reductase [Glycine max] 344 8e-93
ref|YP_348659.1| glutathione reductase [Pseudomonas fluores... 344 8e-93
ref|YP_425773.1| Glutathione reductase [Rhodospirillum rubr... 343 1e-92
ref|YP_421029.1| Glutathione reductase [Magnetospirillum ma... 343 2e-92
ref|NP_888964.1| glutathione reductase [Bordetella bronchis... 343 2e-92
sp|P48640|GSHRP_SOYBN Glutathione reductase, chloroplast pr... 343 2e-92
ref|YP_001669762.1| glutathione-disulfide reductase [Pseudo... 343 2e-92
ref|ZP_00207996.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 343 2e-92
ref|NP_745949.1| glutathione reductase [Pseudomonas putida ... 342 3e-92
ref|YP_001172620.1| glutathione reductase [Pseudomonas stut... 342 3e-92
ref|YP_001750047.1| glutathione-disulfide reductase [Pseudo... 342 4e-92
ref|ZP_00415841.1| FAD-dependent pyridine nucleotide-disulp... 342 4e-92
gb|AAD28177.1|AF109694_1 glutathione reductase [Brassica ju... 342 4e-92
ref|NP_880776.1| glutathione reductase [Bordetella pertussi... 341 7e-92
ref|YP_001370639.1| glutathione-disulfide reductase [Ochrob... 341 7e-92
ref|YP_001267277.1| glutathione reductase [Pseudomonas puti... 341 8e-92
ref|YP_486991.1| Glutathione reductase [Rhodopseudomonas pa... 341 9e-92
gb|EDT30877.1| glutathione-disulfide reductase [Oligotropha... 340 1e-91
ref|YP_001525250.1| glutathione reductase [Azorhizobium cau... 340 2e-91
gb|ABF29525.1| dual-targeted glutathione reductase [Phaseol... 339 2e-91
gb|ACO66041.1| predicted protein [Micromonas sp. RCC299] 339 4e-91
ref|YP_221728.1| glutathione reductase [Brucella abortus bi... 339 4e-91
ref|NP_539889.2| glutathione reductase [Brucella melitensis... 338 4e-91
ref|NP_698019.1| glutathione reductase [Brucella suis 1330]... 338 4e-91
gb|AAL52153.1| GLUTATHIONE REDUCTASE [Brucella melitensis 16M] 338 4e-91
gb|AAK96868.1| Gluthatione reductase, chloroplast precursor... 338 6e-91
emb|CAM76458.1| Glutathione reductase, plant [Magnetospiril... 338 7e-91
ref|YP_001627684.1| glutathione-disulfide reductase [Brucel... 338 7e-91
ref|YP_001592851.1| glutathione-disulfide reductase [Brucel... 337 9e-91
ref|YP_001602461.1| Glutathione reductase [Gluconacetobacte... 337 9e-91
ref|ZP_01545488.1| glutathione reductase [Stappia aggregata... 337 1e-90
ref|ZP_01459814.1| glutathione-disulfide reductase [Stigmat... 337 1e-90
ref|XP_802453.1| trypanothione reductase, putative [Trypano... 337 1e-90
ref|YP_607911.1| glutathione reductase [Pseudomonas entomop... 337 1e-90
ref|YP_001258952.1| glutathione reductase [Brucella ovis AT... 337 1e-90
ref|NP_191026.1| GR (GLUTATHIONE REDUCTASE); glutathione-di... 337 2e-90
sp|Q43154|GSHRP_SPIOL Glutathione reductase, chloroplast pr... 336 2e-90
emb|CAO71585.1| unnamed protein product [Vitis vinifera] 336 2e-90
ref|YP_001412373.1| glutathione-disulfide reductase [Parvib... 336 3e-90
ref|ZP_01039439.1| pyruvate/2-oxoglutarate dehydrogenase co... 335 6e-90
ref|YP_001239484.1| glutathione reductase [Bradyrhizobium s... 335 7e-90
ref|YP_001832020.1| glutathione-disulfide reductase [Beijer... 335 7e-90
sp|O04955|GSHRC_BRARP Glutathione reductase, cytosolic (GR)... 335 7e-90
ref|YP_001659640.1| glutathione reductase [Microcystis aeru... 334 9e-90
ref|ZP_03875623.1| NADPH-glutathione reductase [Haliangium ... 334 1e-89
sp|P27456|GSHRP_PEA Glutathione reductase, chloroplast/mito... 333 1e-89
dbj|BAD27393.1| glutathione reductase [Zinnia elegans] 333 1e-89
ref|YP_343613.1| glutathione reductase [Nitrosococcus ocean... 333 2e-89
emb|CAA42921.1| glutathione reductase (NADPH) [Pisum sativum] 333 2e-89
emb|CAO91430.1| gor [Microcystis aeruginosa PCC 7806] 333 2e-89
ref|NP_001048485.1| Os02g0813500 [Oryza sativa (japonica cu... 332 4e-89
ref|NP_770397.1| glutathione reductase [Bradyrhizobium japo... 332 4e-89
dbj|BAD27394.1| glutathione reductase [Zinnia elegans] 332 6e-89
ref|ZP_01520321.1| pyridine nucleotide-disulphide oxidoredu... 331 7e-89
sp|Q43621|GSHRC_PEA Glutathione reductase, cytosolic (GR) (... 331 1e-88
ref|YP_001235101.1| pyridine nucleotide-disulphide oxidored... 330 1e-88
ref|YP_569193.1| Glutathione reductase [Rhodopseudomonas pa... 330 2e-88
ref|ZP_01304178.1| pyridine nucleotide-disulphide oxidoredu... 330 2e-88
ref|YP_001206659.1| glutathione reductase [Bradyrhizobium s... 330 2e-88
ref|ZP_01046382.1| glutathione reductase [Nitrobacter sp. N... 329 3e-88
gb|ABI35910.1| glutathione reductase [Rheum australe] 329 3e-88
ref|ZP_02941407.1| glutathione-disulfide reductase [Cyanoth... 329 3e-88
ref|ZP_01629769.1| glutathione reductase [Nodularia spumige... 329 4e-88
gb|ABQ53155.1| chloroplast glutathione reductase [Dasypyrum... 328 4e-88
ref|YP_616265.1| glutathione reductase [Sphingopyxis alaske... 328 5e-88
gb|EEH55587.1| predicted protein [Micromonas pusilla CCMP1545] 328 6e-88
ref|NP_354605.2| glutathione reductase [Agrobacterium tumef... 328 7e-88
ref|ZP_01225841.1| putative glutathione reductase [Aurantim... 327 2e-87
gb|ABK95991.1| unknown [Populus trichocarpa] 326 2e-87
ref|YP_001120918.1| glutathione-disulfide reductase [Burkho... 326 2e-87
ref|YP_469884.1| glutathione reductase [Rhizobium etli CFN ... 326 3e-87
ref|YP_527323.1| glutathione reductase [Saccharophagus degr... 325 4e-87
gb|ABB89042.1| glutathione reductase [Vigna unguiculata] 325 4e-87
ref|YP_457865.1| pyruvate/2-oxoglutarate dehydrogenase comp... 325 5e-87
gb|EAZ16075.1| hypothetical protein OsJ_030284 [Oryza sativ... 325 6e-87
gb|EAY78480.1| hypothetical protein OsI_032439 [Oryza sativ... 325 7e-87
dbj|BAA11214.1| Glutathione Reductase [Oryza sativa Japonic... 325 7e-87
ref|YP_001581181.1| glutathione-disulfide reductase [Burkho... 324 8e-87
ref|ZP_02300325.1| glutathione-disulfide reductase [Rhodops... 323 1e-86
ref|YP_780913.1| glutathione-disulfide reductase [Rhodopseu... 323 2e-86
ref|ZP_02976230.1| glutathione-disulfide reductase [Cyanoth... 323 2e-86
ref|YP_001263216.1| pyridine nucleotide-disulphide oxidored... 323 2e-86
ref|NP_947328.1| putative glutathione reductase [Rhodopseud... 323 2e-86
ref|ZP_00987704.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 323 3e-86
ref|ZP_01114352.1| glutathione reductase [Reinekea sp. MED2... 322 4e-86
ref|YP_440830.1| glutathione-disulfide reductase [Burkholde... 321 8e-86
ref|XP_001769571.1| predicted protein [Physcomitrella paten... 321 1e-85
gb|ABB88584.1| glutathione reductase [Ulva fasciata] 321 1e-85
ref|ZP_01625531.1| glutathione reductase [marine gamma prot... 321 1e-85
gb|AAK25938.1|AF360228_1 putative glutathione reductase [Ar... 320 1e-85
ref|YP_274470.1| glutathione reductase [Pseudomonas syringa... 320 2e-85
ref|NP_189059.1| ATGR1 (GLUTATHIONE-DISULFIDE REDUCTASE); g... 320 2e-85
ref|NP_385960.1| glutathione reductase [Sinorhizobium melil... 320 2e-85
ref|YP_674022.1| glutathione reductase [Mesorhizobium sp. B... 320 2e-85
ref|YP_001327247.1| glutathione reductase [Sinorhizobium me... 320 2e-85
dbj|BAF80309.1| cytosolic glutathione reductase [Hordeum vu... 320 2e-85
ref|YP_370590.1| Glutathione reductase [Burkholderia sp. 38... 320 2e-85
ref|YP_756204.1| glutathione-disulfide reductase [Maricauli... 319 4e-85
ref|YP_002826217.1| glutathione reductase [Rhizobium sp. NG... 318 4e-85
ref|YP_001617210.1| Glutathione-disulfide reductase [Sorang... 318 7e-85
dbj|BAD14936.1| glutathione reductase [Brassica oleracea] 318 8e-85
ref|YP_531951.1| Glutathione reductase [Rhodopseudomonas pa... 318 8e-85
ref|ZP_00952278.1| glutathione reductase [Oceanicaulis alex... 318 9e-85
ref|ZP_00980913.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 317 1e-84
ref|YP_106924.1| glutathione reductase [Burkholderia pseudo... 317 1e-84
ref|XP_001696579.1| glutathione reductase [Chlamydomonas re... 317 2e-84
ref|NP_792904.1| glutathione reductase [Pseudomonas syringa... 317 2e-84
gb|AAQ64632.1| cytosolic glutathione reductase [Triticum mo... 317 2e-84
ref|ZP_01616723.1| glutathione reductase [marine gamma prot... 317 2e-84
ref|YP_236051.1| glutathione reductase [Pseudomonas syringa... 317 2e-84
ref|YP_001064600.1| glutathione-disulfide reductase [Burkho... 316 2e-84
ref|YP_622264.1| Glutathione reductase [Burkholderia cenoce... 316 3e-84
ref|YP_497084.1| pyridine nucleotide-disulphide oxidoreduct... 316 3e-84
gb|ABB89041.1| glutathione reductase [Vigna unguiculata] 316 3e-84
ref|YP_001341220.1| pyridine nucleotide-disulphide oxidored... 315 4e-84
ref|YP_630538.1| glutathione-disulfide reductase [Myxococcu... 315 7e-84
ref|XP_001416175.1| glutathione reductase [Ostreococcus luc... 315 8e-84
ref|YP_001766305.1| glutathione-disulfide reductase [Burkho... 314 9e-84
ref|ZP_00631448.1| FAD-dependent pyridine nucleotide-disulp... 314 1e-83
gb|AAR05955.1| ORFG [Sphingomonas paucimobilis] 314 1e-83
ref|ZP_02908997.1| glutathione-disulfide reductase [Burkhol... 314 1e-83
ref|YP_774940.1| glutathione-disulfide reductase [Burkholde... 313 1e-83
ref|YP_786142.1| glutathione reductase [Bordetella avium 19... 313 1e-83
ref|ZP_02858777.1| glutathione-disulfide reductase [Rhizobi... 313 2e-83
ref|YP_001809607.1| glutathione-disulfide reductase [Burkho... 313 2e-83
ref|YP_001632335.1| probable glutathione reductase [Bordete... 313 2e-83
ref|YP_759435.1| glutathione-disulfide reductase [Hyphomona... 313 2e-83
ref|ZP_01892670.1| glutathione reductase [Marinobacter algi... 313 3e-83
ref|ZP_01865059.1| pyruvate/2-oxoglutarate dehydrogenase co... 312 3e-83
ref|YP_033472.1| glutathione reductase [Bartonella henselae... 312 4e-83
ref|ZP_02295236.1| glutathione-disulfide reductase [Rhizobi... 312 4e-83
ref|ZP_02892722.1| glutathione-disulfide reductase [Burkhol... 311 5e-83
sp|P48639|GSHR_BURCE Glutathione reductase (GR) (GRase) >gi... 311 5e-83
ref|YP_001021315.1| glutathione reductase [Methylibium petr... 311 6e-83
ref|YP_768279.1| glutathione reductase [Rhizobium leguminos... 310 1e-82
ref|ZP_01737440.1| glutathione reductase [Marinobacter sp. ... 310 2e-82
ref|ZP_02380988.1| Glutathione reductase [Burkholderia ubon... 310 2e-82
ref|YP_295698.1| Glutathione reductase, plant [Ralstonia eu... 309 3e-82
ref|YP_958634.1| pyridine nucleotide-disulphide oxidoreduct... 309 3e-82
ref|YP_032317.1| glutathione reductase [Bartonella quintana... 308 5e-82
ref|ZP_00514499.1| Glutathione reductase, plant [Crocosphae... 308 6e-82
ref|YP_192159.1| Glutathione reductase [Gluconobacter oxyda... 308 6e-82
ref|YP_988912.1| glutathione reductase [Bartonella bacillif... 307 1e-81
ref|ZP_01078137.1| glutathione reductase [Marinomonas sp. M... 307 1e-81
ref|YP_001685169.1| glutathione-disulfide reductase [Caulob... 306 2e-81
ref|YP_001517987.1| glutathione-disulfide reductase [Acaryo... 306 2e-81
ref|YP_693143.1| glutathione reductase [Alcanivorax borkume... 306 2e-81
ref|YP_001609327.1| glutathione reductase [Bartonella tribo... 306 3e-81
ref|ZP_01104150.1| trypanothione reductase [gamma proteobac... 306 3e-81
gb|ABF29524.1| cytosolic glutathione reductase [Phaseolus v... 305 4e-81
ref|YP_435071.1| glutathione-disulfide reductase [Hahella c... 305 4e-81
ref|YP_745248.1| glutathione reductase [Granulibacter bethe... 304 9e-81
ref|ZP_02122325.1| glutathione-disulfide reductase [Methylo... 303 2e-80
emb|CAC13956.1| glutathione reductase [Mesembryanthemum cry... 303 2e-80
ref|YP_001639767.1| pyridine nucleotide-disulphide oxidored... 303 3e-80
ref|ZP_01877738.1| glutathione-disulfide reductase [Roseova... 303 3e-80
ref|ZP_01623681.1| glutathione reductase [Lyngbya sp. PCC 8... 302 5e-80
ref|YP_001806040.1| glutathione reductase [Cyanothece sp. A... 302 5e-80
ref|NP_421105.1| glutathione reductase [Caulobacter crescen... 302 5e-80
ref|ZP_01449108.1| glutathione-disulfide reductase [alpha p... 301 8e-80
ref|ZP_02841341.1| glutathione-disulfide reductase [Thauera... 301 8e-80
ref|NP_489008.1| glutathione reductase [Nostoc sp. PCC 7120... 301 1e-79
ref|ZP_01755695.1| glutathione-disulfide reductase [Roseoba... 301 1e-79
ref|YP_724176.1| glutathione reductase [Trichodesmium eryth... 301 1e-79
ref|YP_001771544.1| glutathione-disulfide reductase [Methyl... 300 1e-79
ref|YP_983762.1| pyridine nucleotide-disulphide oxidoreduct... 300 1e-79
ref|NP_682398.1| glutathione reductase [Thermosynechococcus... 300 1e-79
ref|YP_162946.1| pyruvate/2-oxoglutarate dehydrogenase comp... 300 1e-79
ref|ZP_02056532.1| pyridine nucleotide-disulphide oxidoredu... 300 2e-79
ref|YP_001219129.1| glutathione oxidoreductase [Candidatus ... 300 2e-79
ref|YP_322757.1| glutathione reductase [Anabaena variabilis... 300 2e-79
ref|ZP_01223838.1| glutathione reductase [marine gamma prot... 300 2e-79
ref|YP_001755363.1| glutathione-disulfide reductase [Methyl... 300 2e-79
ref|ZP_01731018.1| glutathione reductase [Cyanothece sp. CC... 299 3e-79
ref|ZP_01901318.1| glutathione-disulfide reductase [Roseoba... 299 3e-79
emb|CAL51999.2| Gr glutathione reductase, probable (IC) [Os... 299 3e-79
emb|CAA61856.1| glutathione reductase (NADPH) [Nostoc sp. P... 298 6e-79
ref|YP_166571.1| glutathione-disulfide reductase [Silicibac... 298 6e-79
emb|CAA12270.1| ORF 4 [Sphingomonas sp. RW5] 297 1e-78
ref|YP_399860.1| glutathione reductase [Synechococcus elong... 297 2e-78
ref|YP_903542.1| pyridine nucleotide-disulphide oxidoreduct... 295 4e-78
ref|ZP_00108447.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 295 4e-78
ref|YP_573926.1| pyridine nucleotide-disulphide oxidoreduct... 295 4e-78
ref|YP_547500.1| pyridine nucleotide-disulphide oxidoreduct... 295 5e-78
ref|YP_001924954.1| pyridine nucleotide-disulphide oxidored... 295 6e-78
ref|YP_171408.1| glutathione reductase [Synechococcus elong... 295 7e-78
ref|YP_405027.1| glutathione reductase [Shigella dysenteria... 295 8e-78
ref|ZP_00998281.1| glutathione-disulfide reductase [Oceanic... 294 1e-77
ref|ZP_01306260.1| glutathione reductase [Oceanobacter sp. ... 293 2e-77
emb|CAA54043.1| glutathione reductase (NADPH) [Nicotiana ta... 290 2e-76
ref|ZP_01741461.1| probable glutathione reductase [Rhodobac... 289 3e-76
ref|ZP_01751062.1| glutathione reductase [Roseobacter sp. C... 289 3e-76
ref|YP_929415.1| glutathione reductase [Shewanella amazonen... 289 3e-76
ref|NP_927730.1| glutathione reductase [Photorhabdus lumine... 289 4e-76
pdb|1GRT|A Chain A, Human Glutathione Reductase A34eR37W MU... 288 6e-76
pdb|2GRT|A Chain A, Human Glutathione Reductase A34e, R37w ... 288 9e-76
ref|ZP_01445717.1| glutathione-disulfide reductase [Roseova... 287 1e-75
ref|ZP_00960040.1| glutathione-disulfide reductase [Roseova... 287 2e-75
ref|YP_001043878.1| glutathione-disulfide reductase [Rhodob... 286 3e-75
ref|ZP_02140744.1| glutathione reductase [Roseobacter litor... 285 4e-75
ref|YP_001337520.1| glutathione reductase [Klebsiella pneum... 285 5e-75
ref|YP_001440238.1| hypothetical protein ESA_04222 [Enterob... 285 6e-75
ref|NP_417957.1| glutathione oxidoreductase [Escherichia co... 285 7e-75
ref|YP_353433.1| probable glutathione reductase [Rhodobacte... 285 7e-75
ref|ZP_01055188.1| glutathione-disulfide reductase [Roseoba... 285 8e-75
emb|CAA53993.1| glutathione reductase [Nicotiana tabacum] 284 9e-75
ref|ZP_00823608.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 284 1e-74
ref|ZP_02958557.1| hypothetical protein PROSTU_00303 [Provi... 284 1e-74
ref|YP_854548.1| glutathione-disulfide reductase [Aeromonas... 284 1e-74
ref|NP_246172.1| glutathione reductase [Pasteurella multoci... 283 2e-74
ref|YP_094614.1| glutathione reductase [Legionella pneumoph... 283 2e-74
ref|YP_001460294.1| glutathione-disulfide reductase [Escher... 283 2e-74
ref|YP_001882115.1| glutathione-disulfide reductase [Shigel... 283 2e-74
ref|ZP_01156525.1| glutathione-disulfide reductase [Oceanic... 283 2e-74
ref|ZP_00711931.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 283 3e-74
ref|YP_682215.1| glutathione reductase [Roseobacter denitri... 283 3e-74
ref|YP_409811.1| glutathione reductase [Shigella boydii Sb2... 283 3e-74
ref|YP_001572974.1| hypothetical protein SARI_04039 [Salmon... 282 4e-74
ref|YP_001139983.1| glutathione oxidoreductase [Aeromonas s... 282 4e-74
ref|XP_001833633.1| hypothetical protein CC1G_03850 [Coprin... 282 5e-74
ref|ZP_02145082.1| Glutathione reductase [Phaeobacter galla... 282 5e-74
ref|ZP_01015598.1| probable glutathione reductase [Rhodobac... 282 5e-74
ref|ZP_00830654.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 282 5e-74
ref|NP_756161.1| glutathione reductase [Escherichia coli CF... 282 6e-74
ref|ZP_02564298.1| hypothetical protein Senten_00700 [Salmo... 281 6e-74
ref|YP_001590614.1| hypothetical protein SPAB_04466 [Salmon... 281 7e-74
ref|ZP_02148155.1| glutathione-disulfide reductase [Phaeoba... 281 8e-74
ref|ZP_02649953.1| glutathione reductase [Salmonella enteri... 281 8e-74
>ref|XP_823260.1| trypanothione reductase [Trypanosoma brucei TREU927]
gb|EAN78432.1| trypanothione reductase [Trypanosoma brucei]
Length = 492
Score = 1008 bits (2607), Expect = 0.0, Method: Composition-based stats.
Identities = 492/492 (100%), Positives = 492/492 (100%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK
Sbjct: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL
Sbjct: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE
Sbjct: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK
Sbjct: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG
Sbjct: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT
Sbjct: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS
Sbjct: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
Query: 481 GEKMEKLPDSNL 492
GEKMEKLPDSNL
Sbjct: 481 GEKMEKLPDSNL 492
>sp|P39051|TYTR_TRYBB Trypanothione reductase (TR) (N(1),N(8)-bis(glutathionyl)spermidine
reductase)
emb|CAA44870.1| trypanothione reductase [Trypanosoma brucei]
Length = 492
Score = 992 bits (2564), Expect = 0.0, Method: Composition-based stats.
Identities = 482/492 (97%), Positives = 487/492 (98%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEAGWNAATLY KRVAV+DVQT HGPP YAALGGTCVNVGCVPK
Sbjct: 1 MSKIFDLVVIGAGSGGLEAGWNAATLYKKRVAVIDVQTHHGPPHYAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL
Sbjct: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPG+EHCISSNE
Sbjct: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGVEHCISSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK
Sbjct: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG
Sbjct: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT
Sbjct: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS
Sbjct: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYY+K
Sbjct: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYLK 480
Query: 481 GEKMEKLPDSNL 492
GEKME LP+S+L
Sbjct: 481 GEKMETLPESSL 492
>sp|P13110|TYTR_TRYCO Trypanothione reductase (TR) (N(1),N(8)-bis(glutathionyl)spermidine
reductase)
gb|AAA30258.1| trypanothione reductase
Length = 492
Score = 888 bits (2294), Expect = 0.0, Method: Composition-based stats.
Identities = 422/492 (85%), Positives = 456/492 (92%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSKAFDLV+IGAGSGGLEAGWNAATLY KRVAVVDVQT HGPPF+AALGGTCVNVGCVPK
Sbjct: 1 MSKAFDLVIIGAGSGGLEAGWNAATLYKKRVAVVDVQTVHGPPFFAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMD LRESAGFGWEFD S++KANWK LIAAKN AVLDINKSYE MF DTEGL
Sbjct: 61 KLMVTGAQYMDQLRESAGFGWEFDASTIKANWKTLIAAKNAAVLDINKSYEDMFKDTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWG+LE KNVV VRE ADPKS VKERLQA+HI++ATGSWPQM IPGIEHCISSNE
Sbjct: 121 EFFLGWGALEQKNVVTVREGADPKSKVKERLQAEHIIIATGSWPQMLKIPGIEHCISSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL EPPRRVLTVGGGFISVEFAGIFNAYKP GGKVTLCYRNN ILRGFD T+R+E+TK
Sbjct: 181 AFYLEEPPRRVLTVGGGFISVEFAGIFNAYKPVGGKVTLCYRNNPILRGFDYTLRQELTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI+IMTNENP+K+ LN DGSKHVTFESGKTLDVDVVMMAIGR+PRT LQL VG
Sbjct: 241 QLVANGIDIMTNENPSKIELNPDGSKHVTFESGKTLDVDVVMMAIGRLPRTGYLQLQTVG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V LT KG +QVDEFSRTNVPNIYAIGD+T R+MLTPVAINEGA++VDT+FG+KPRKTDHT
Sbjct: 301 VNLTDKGAIQVDEFSRTNVPNIYAIGDVTGRIMLTPVAINEGASVVDTIFGSKPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGL EE AAK FEKVAVY+S FTPLMHNISGSKYKKFVAKI+T+H
Sbjct: 361 RVASAVFSIPPIGTCGLTEEEAAKSFEKVAVYLSCFTPLMHNISGSKYKKFVAKIITDHG 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTV+GVHLLGD +PEIIQAVG+C++LNAKISDFYNTIGVHPTSAEELCSMRTPS+YY+K
Sbjct: 421 DGTVVGVHLLGDSSPEIIQAVGICMKLNAKISDFYNTIGVHPTSAEELCSMRTPSHYYIK 480
Query: 481 GEKMEKLPDSNL 492
GEKME LPDS+L
Sbjct: 481 GEKMETLPDSSL 492
>sp|P28593|TYTR_TRYCR Trypanothione reductase (TR) (N(1),N(8)-bis(glutathionyl)spermidine
reductase)
gb|AAA63547.1| trypanothione reductase
Length = 492
Score = 856 bits (2211), Expect = 0.0, Method: Composition-based stats.
Identities = 409/492 (83%), Positives = 447/492 (90%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPK
Sbjct: 2 MSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPK 61
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYM+HLRESAGFGWEFD ++++A WKKLIA K+EAVL+INKSYE MF DTEGL
Sbjct: 62 KLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGL 121
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWGSLESKNVV VRE+ADP SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNE
Sbjct: 122 EFFLGWGSLESKNVVNVRESADPASAVKERLETENILLASGSWPHMPNIPGIEHCISSNE 181
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TK
Sbjct: 182 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 241
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N G
Sbjct: 242 QLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAG 301
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V + GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHT
Sbjct: 302 V-MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLIEEVA+K +E VAVY+SSFTPLMHNISGSKYK FVAKI+TNHS
Sbjct: 361 RVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHS 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGD APEIIQ VG+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 421 DGTVLGVHLLGDNAPEIIQGVGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
Query: 481 GEKMEKLPDSNL 492
GEKMEK +++L
Sbjct: 481 GEKMEKPSEASL 492
>pdb|1NDA|A Chain A, The Structure Of Trypanosoma Cruzi Trypanothione Reductase
In The Oxidized And Nadph Reduced State
pdb|1NDA|B Chain B, The Structure Of Trypanosoma Cruzi Trypanothione Reductase
In The Oxidized And Nadph Reduced State
pdb|1NDA|C Chain C, The Structure Of Trypanosoma Cruzi Trypanothione Reductase
In The Oxidized And Nadph Reduced State
pdb|1NDA|D Chain D, The Structure Of Trypanosoma Cruzi Trypanothione Reductase
In The Oxidized And Nadph Reduced State
Length = 491
Score = 856 bits (2211), Expect = 0.0, Method: Composition-based stats.
Identities = 409/492 (83%), Positives = 447/492 (90%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPK
Sbjct: 1 MSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYM+HLRESAGFGWEFD ++++A WKKLIA K+EAVL+INKSYE MF DTEGL
Sbjct: 61 KLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWGSLESKNVV VRE+ADP SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNE
Sbjct: 121 EFFLGWGSLESKNVVNVRESADPASAVKERLETENILLASGSWPHMPNIPGIEHCISSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TK
Sbjct: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N G
Sbjct: 241 QLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V + GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHT
Sbjct: 301 V-MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHT 359
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLIEEVA+K +E VAVY+SSFTPLMHNISGSKYK FVAKI+TNHS
Sbjct: 360 RVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHS 419
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGD APEIIQ VG+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 420 DGTVLGVHLLGDNAPEIIQGVGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 479
Query: 481 GEKMEKLPDSNL 492
GEKMEK +++L
Sbjct: 480 GEKMEKPSEASL 491
>ref|XP_805296.1| trypanothione reductase [Trypanosoma cruzi strain CL Brener]
gb|EAN83445.1| trypanothione reductase, putative [Trypanosoma cruzi]
Length = 492
Score = 852 bits (2202), Expect = 0.0, Method: Composition-based stats.
Identities = 406/492 (82%), Positives = 446/492 (90%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPK
Sbjct: 2 MSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPK 61
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYM+HLRESAGFGWEFD ++++A WKKLIA K+EAVL+INKSYE MF DTEGL
Sbjct: 62 KLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGL 121
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWGSLESKNVV VRE+ADP SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNE
Sbjct: 122 EFFLGWGSLESKNVVNVRESADPASAVKERLETENILLASGSWPHMPNIPGIEHCISSNE 181
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TK
Sbjct: 182 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 241
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N G
Sbjct: 242 QLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAG 301
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V + GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDT+FG PRKTDHT
Sbjct: 302 V-MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTIFGTTPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLIEEVA+K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHS
Sbjct: 361 RVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHS 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGD APEIIQ VG+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 421 DGTVLGVHLLGDNAPEIIQGVGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
Query: 481 GEKMEKLPDSNL 492
GEKMEK +++L
Sbjct: 481 GEKMEKPSEASL 492
>pdb|1GXF|A Chain A, Crystal Structure Of Trypanosoma Cruzi Trypanothione
Reductase In Complex With The Inhibitor Quinacrine
Mustard
pdb|1GXF|B Chain B, Crystal Structure Of Trypanosoma Cruzi Trypanothione
Reductase In Complex With The Inhibitor Quinacrine
Mustard
emb|CAA78360.1| trypanothione reductase [Trypanosoma cruzi]
Length = 492
Score = 852 bits (2202), Expect = 0.0, Method: Composition-based stats.
Identities = 405/492 (82%), Positives = 445/492 (90%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPK
Sbjct: 2 MSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPK 61
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYM+HLRESAGFGWEFD ++++A WK LIA K+EAVL+INKSY+ MF DTEGL
Sbjct: 62 KLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTEGL 121
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWGSLESKNVV VRE+ADP SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNE
Sbjct: 122 EFFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNE 181
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TK
Sbjct: 182 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 241
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N G
Sbjct: 242 QLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAG 301
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V + GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHT
Sbjct: 302 V-MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLIEEVA+K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHS
Sbjct: 361 RVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHS 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGD APEIIQ +G+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 421 DGTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
Query: 481 GEKMEKLPDSNL 492
GEKMEK +++L
Sbjct: 481 GEKMEKPSEASL 492
>pdb|1BZL|A Chain A, Crystal Structure Of Trypanosoma Cruzi Trypanothione
Reductase In Complex With Trypanothione, And The
Structure- Based Discovery Of New Natural Product
Inhibitors
pdb|1BZL|B Chain B, Crystal Structure Of Trypanosoma Cruzi Trypanothione
Reductase In Complex With Trypanothione, And The
Structure- Based Discovery Of New Natural Product
Inhibitors
Length = 486
Score = 851 bits (2198), Expect = 0.0, Method: Composition-based stats.
Identities = 404/486 (83%), Positives = 441/486 (90%), Gaps = 1/486 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPK
Sbjct: 1 MSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYM+HLRESAGFGWEFD ++++A WK LIA K+EAVL+INKSY+ MF DTEGL
Sbjct: 61 KLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWGSLESKNVV VRE+ADP SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNE
Sbjct: 121 EFFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TK
Sbjct: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N G
Sbjct: 241 QLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V + GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHT
Sbjct: 301 V-MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHT 359
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
RVASAVFSIPPIGTCGLIEEVA+K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHS
Sbjct: 360 RVASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHS 419
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DGTVLGVHLLGD APEIIQ +G+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK
Sbjct: 420 DGTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 479
Query: 481 GEKMEK 486
GEKMEK
Sbjct: 480 GEKMEK 485
>pdb|1AOG|A Chain A, Trypanosoma Cruzi Trypanothione Reductase (Oxidized Form)
pdb|1AOG|B Chain B, Trypanosoma Cruzi Trypanothione Reductase (Oxidized Form)
Length = 485
Score = 848 bits (2191), Expect = 0.0, Method: Composition-based stats.
Identities = 403/485 (83%), Positives = 440/485 (90%), Gaps = 1/485 (0%)
Query: 2 SKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKK 61
SK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKK
Sbjct: 1 SKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKK 60
Query: 62 LMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLD 121
LMVTGAQYM+HLRESAGFGWEFD ++++A WK LIA K+EAVL+INKSY+ MF DTEGL+
Sbjct: 61 LMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTEGLE 120
Query: 122 FFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEA 181
FFLGWGSLESKNVV VRE+ADP SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEA
Sbjct: 121 FFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEA 180
Query: 182 FYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQ 241
FYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQ
Sbjct: 181 FYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQ 240
Query: 242 LTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGV 301
LTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N GV
Sbjct: 241 LTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV 300
Query: 302 KLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTR 361
+ GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTR
Sbjct: 301 -MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTR 359
Query: 362 VASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSD 421
VASAVFSIPPIGTCGLIEEVA+K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSD
Sbjct: 360 VASAVFSIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSD 419
Query: 422 GTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKG 481
GTVLGVHLLGD APEIIQ +G+CL+LNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKG
Sbjct: 420 GTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKG 479
Query: 482 EKMEK 486
EKMEK
Sbjct: 480 EKMEK 484
>gb|AAB59211.1| trypanothione reductase [Trypanosoma cruzi]
Length = 453
Score = 788 bits (2034), Expect = 0.0, Method: Composition-based stats.
Identities = 374/454 (82%), Positives = 411/454 (90%), Gaps = 1/454 (0%)
Query: 8 VVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGA 67
VVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGA
Sbjct: 1 VVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGA 60
Query: 68 QYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWG 127
QYM+HLRESAGFGWEFD ++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWG
Sbjct: 61 QYMEHLRESAGFGWEFDRTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWG 120
Query: 128 SLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEP 187
SLESKNVV VRE+ADP SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEP
Sbjct: 121 SLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEP 180
Query: 188 PRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGI 247
PRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI
Sbjct: 181 PRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGI 240
Query: 248 EIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKG 307
+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + G
Sbjct: 241 QILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNG 299
Query: 308 GVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVF 367
GVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVF
Sbjct: 300 GVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVF 359
Query: 368 SIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGV 427
SIPPIGTCGLIEEVA+K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGV
Sbjct: 360 SIPPIGTCGLIEEVASKRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGV 419
Query: 428 HLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVH 461
HLLGD APEIIQ +G+CL+LNAKISDFYNTIGVH
Sbjct: 420 HLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVH 453
>gb|AAK71224.1|AF359006_1 trypanothione reductase [Trypanosoma cruzi marinkellei]
gb|AAK71225.1|AF359007_1 trypanothione reductase [Trypanosoma cruzi marinkellei]
Length = 430
Score = 754 bits (1947), Expect = 0.0, Method: Composition-based stats.
Identities = 357/431 (82%), Positives = 394/431 (91%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIAAK+EAVL+INKSYE MF DTEGL+FF+GWGSLESKNVV VRE+ADP
Sbjct: 61 RTTIRAEWKKLIAAKDEAVLNINKSYEEMFRDTEGLEFFMGWGSLESKNVVNVRESADPS 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HIL+A+GSWP MP IPGIEHC+SSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILVASGSWPHMPNIPGIEHCVSSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VM+AIGR PRTNDLQL N GV +T G VQVDE+SRTNVPNIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMIAIGRSPRTNDLQLQNAGV-ITKNGAVQVDEYSRTNVPNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAK 384
IGD+T+R+MLTPVAINEGAALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+K
Sbjct: 300 IGDVTNRVMLTPVAINEGAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 EFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
+E VAVY+SSFTPLMHNISGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VGVC
Sbjct: 360 RYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGVC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gb|AAK71210.1|AF358992_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71211.1|AF358993_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71212.1|AF358994_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71213.1|AF358995_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71215.1|AF358997_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71217.1|AF358999_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71219.1|AF359001_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71221.1|AF359003_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71223.1|AF359005_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 747 bits (1928), Expect = 0.0, Method: Composition-based stats.
Identities = 355/431 (82%), Positives = 390/431 (90%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETENILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAK 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+K
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 EFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
+E VAVY+SSFTPLMHNISGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+C
Sbjct: 360 RYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gb|AAK71204.1|AF358986_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 747 bits (1928), Expect = 0.0, Method: Composition-based stats.
Identities = 354/431 (82%), Positives = 389/431 (90%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAK 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+K
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 EFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
+E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gb|AAK71206.1|AF358988_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71207.1|AF358989_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71209.1|AF358991_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71214.1|AF358996_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71216.1|AF358998_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71218.1|AF359000_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71220.1|AF359002_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71222.1|AF359004_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 746 bits (1927), Expect = 0.0, Method: Composition-based stats.
Identities = 353/431 (81%), Positives = 389/431 (90%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAK 384
IGD+T+R+MLTPVAINE AALVDT+FG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+K
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTIFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 EFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
+E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gb|AAK71199.1|AF358981_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71205.1|AF358987_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 746 bits (1925), Expect = 0.0, Method: Composition-based stats.
Identities = 352/431 (81%), Positives = 389/431 (90%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKDGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAK 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+K
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 EFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
+E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gb|AAK71187.1|AF358969_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71188.1|AF358970_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71190.1|AF358972_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71191.1|AF358973_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71192.1|AF358974_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71193.1|AF358975_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71194.1|AF358976_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71195.1|AF358977_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71196.1|AF358978_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71197.1|AF358979_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71198.1|AF358980_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71200.1|AF358982_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71201.1|AF358983_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71202.1|AF358984_1 trypanothione reductase [Trypanosoma cruzi]
gb|AAK71203.1|AF358985_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 745 bits (1924), Expect = 0.0, Method: Composition-based stats.
Identities = 352/431 (81%), Positives = 389/431 (90%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAK 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+K
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 EFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
+E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gb|AAX40393.1| trypanothione reductase [Trypanosoma cruzi]
gb|AAX40394.1| trypanothione reductase [Trypanosoma cruzi]
gb|AAX40395.1| trypanothione reductase [Trypanosoma cruzi]
gb|AAX40396.1| trypanothione reductase [Trypanosoma cruzi]
gb|AAX40397.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 745 bits (1924), Expect = 0.0, Method: Composition-based stats.
Identities = 355/431 (82%), Positives = 390/431 (90%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETENILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAA 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 KEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
K +E VAVY+SSFTPLMHNISGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+
Sbjct: 360 KRYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gb|AAX40409.1| trypanothione reductase [Trypanosoma cruzi]
gb|AAX40411.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 745 bits (1923), Expect = 0.0, Method: Composition-based stats.
Identities = 353/431 (81%), Positives = 389/431 (90%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAA 383
AIGD+T+R+MLTPVAINE AALVDT+FG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTIFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 KEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+
Sbjct: 360 KRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gb|AAX40408.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 745 bits (1923), Expect = 0.0, Method: Composition-based stats.
Identities = 353/431 (81%), Positives = 389/431 (90%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKEMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAA 383
AIGD+T+R+MLTPVAINE AALVDT+FG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTIFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 KEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+
Sbjct: 360 KRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gb|AAK71208.1|AF358990_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 745 bits (1923), Expect = 0.0, Method: Composition-based stats.
Identities = 352/431 (81%), Positives = 388/431 (90%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTAN I+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANSIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAK 384
IGD+T+R+MLTPVAINE AALVDT+FG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+K
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTIFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 EFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
+E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gb|AAX40399.1| trypanothione reductase [Trypanosoma cruzi]
gb|AAX40401.1| trypanothione reductase [Trypanosoma cruzi]
gb|AAX40403.1| trypanothione reductase [Trypanosoma cruzi]
gb|AAX40404.1| trypanothione reductase [Trypanosoma cruzi]
gb|AAX40405.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 744 bits (1920), Expect = 0.0, Method: Composition-based stats.
Identities = 352/431 (81%), Positives = 389/431 (90%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAA 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 KEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+
Sbjct: 360 KRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gb|AAK71226.1|AF359008_1 trypanothione reductase [Trypanosoma vespertilionis]
Length = 430
Score = 743 bits (1919), Expect = 0.0, Method: Composition-based stats.
Identities = 352/431 (81%), Positives = 389/431 (90%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA+K+EAVL+INKSYE MF DTEGL+FF+GWGSLESKNVV VRE+A+P
Sbjct: 61 RTTLRAEWKKLIASKDEAVLNINKSYEEMFRDTEGLEFFMGWGSLESKNVVNVRESAEPD 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T +NPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTVREELTKQLTANGIQILTKDNPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GVQVDE+SRTNVPNIYA
Sbjct: 241 SKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNSGVQVDEYSRTNVPNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAK 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+K
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 EFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
+E VAVY+SSFTPLMH ISGS YK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VGVC
Sbjct: 360 RYEVVAVYLSSFTPLMHKISGSNYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGVC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gb|AAK71189.1|AF358971_1 trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 743 bits (1919), Expect = 0.0, Method: Composition-based stats.
Identities = 351/431 (81%), Positives = 389/431 (90%), Gaps = 1/431 (0%)
Query: 25 TLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFD 84
TLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEFD
Sbjct: 1 TLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEFD 60
Query: 85 GSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADPK 144
++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 RTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADPA 120
Query: 145 SAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 204
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA
Sbjct: 121 SAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEFA 180
Query: 205 GIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTDG 264
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN DG
Sbjct: 181 GIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNADG 240
Query: 265 SKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYA 324
SK VTFESGK ++ D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIYA
Sbjct: 241 SKSVTFESGKKMEFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIYA 299
Query: 325 IGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAK 384
IGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+K
Sbjct: 300 IGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVASK 359
Query: 385 EFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVC 444
+E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+C
Sbjct: 360 RYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGIC 419
Query: 445 LRLNAKISDFY 455
L+LNAKISDFY
Sbjct: 420 LKLNAKISDFY 430
>gb|AAX40400.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 742 bits (1915), Expect = 0.0, Method: Composition-based stats.
Identities = 351/431 (81%), Positives = 388/431 (90%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNE FYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEGFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAA 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 KEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+
Sbjct: 360 KRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gb|AAX40410.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 742 bits (1915), Expect = 0.0, Method: Composition-based stats.
Identities = 354/431 (82%), Positives = 389/431 (90%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ ++ILLA+GSWP MP I GIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETENILLASGSWPHMPNILGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAA 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 KEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
K +E VAVY+SSFTPLMHNISGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+
Sbjct: 360 KRYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gb|AAX40402.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 742 bits (1915), Expect = 0.0, Method: Composition-based stats.
Identities = 351/431 (81%), Positives = 388/431 (90%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SR NV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRMNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAA 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 KEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+
Sbjct: 360 KRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gb|AAX40392.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 741 bits (1913), Expect = 0.0, Method: Composition-based stats.
Identities = 354/431 (82%), Positives = 388/431 (90%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCV KKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVQKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVREGADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETENILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAA 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 KEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
K +E VAVY+SSFTPLMHNISGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+
Sbjct: 360 KRYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gb|AAX40398.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 740 bits (1911), Expect = 0.0, Method: Composition-based stats.
Identities = 350/431 (81%), Positives = 387/431 (89%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ LGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSVLGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
GIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 VGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAA 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 KEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+
Sbjct: 360 KRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gb|AAX40406.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 739 bits (1908), Expect = 0.0, Method: Composition-based stats.
Identities = 352/431 (81%), Positives = 387/431 (89%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A W KLIA K+EAVL+INKSYE MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWTKLIAVKDEAVLNINKSYEEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ ++ILLA+GSWP MP IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETENILLASGSWPHMPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLT NGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTTNGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQL N GV + GVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAGV-MIKNSGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAA 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTNPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 KEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
K +E VAVY+SSFTPLMHNISGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ VG+
Sbjct: 360 KRYEVVAVYLSSFTPLMHNISGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGVGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>gb|AAX40407.1| trypanothione reductase [Trypanosoma cruzi]
Length = 430
Score = 738 bits (1906), Expect = 0.0, Method: Composition-based stats.
Identities = 350/431 (81%), Positives = 388/431 (90%), Gaps = 1/431 (0%)
Query: 24 ATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGAQYMDHLRESAGFGWEF 83
ATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPKKLMVTGAQYM+HLRESAGFGWEF
Sbjct: 1 ATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKLMVTGAQYMEHLRESAGFGWEF 60
Query: 84 DGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWGSLESKNVVVVRETADP 143
D ++++A WKKLIA K+EAVL+INKSY+ MF DTEGL+FFLGWGSLESKNVV VRE+ADP
Sbjct: 61 DRTTLRAEWKKLIAVKDEAVLNINKSYDEMFRDTEGLEFFLGWGSLESKNVVNVRESADP 120
Query: 144 KSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 203
SAVKERL+ +HILLA+GSWP +P IPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF
Sbjct: 121 ASAVKERLETEHILLASGSWPHIPNIPGIEHCISSNEAFYLPEPPRRVLTVGGGFISVEF 180
Query: 204 AGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKVSLNTD 263
AGIFNAYKP G+VTLCYR +ILRGFD T+REE+TKQLTANGI+I+T ENPAKV LN D
Sbjct: 181 AGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTKQLTANGIQILTKENPAKVELNAD 240
Query: 264 GSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIY 323
GSK VTFESGK +D D+VMMAIGR PRT DLQ N GV + GGVQVDE+SRTNV NIY
Sbjct: 241 GSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQPQNAGV-MIKNGGVQVDEYSRTNVSNIY 299
Query: 324 AIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVFSIPPIGTCGLIEEVAA 383
AIGD+T+R+MLTPVAINE AALVDTVFG PRKTDHTRVASAVFSIPPIGTCGLIEEVA+
Sbjct: 300 AIGDVTNRVMLTPVAINEAAALVDTVFGTTPRKTDHTRVASAVFSIPPIGTCGLIEEVAS 359
Query: 384 KEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGV 443
K +E VAVY+SSFTPLMH +SGSKYK FVAKI+TNHSDGTVLGVHLLGD APEIIQ +G+
Sbjct: 360 KRYEVVAVYLSSFTPLMHKVSGSKYKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGI 419
Query: 444 CLRLNAKISDF 454
CL+LNAKISDF
Sbjct: 420 CLKLNAKISDF 430
>pdb|1TYP|A Chain A, Substrate Interactions Between Trypanothione Reductase And
N1-Glutathionylspermidine Disulphide At 0.28-Nm
Resolution
pdb|1TYP|B Chain B, Substrate Interactions Between Trypanothione Reductase And
N1-Glutathionylspermidine Disulphide At 0.28-Nm
Resolution
Length = 487
Score = 732 bits (1889), Expect = 0.0, Method: Composition-based stats.
Identities = 341/487 (70%), Positives = 408/487 (83%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MS+A+DLVVIGAGSGGLEAGWNAA+L+ KRVAV+D+Q HGPP YAALGGTCVNVGCVPK
Sbjct: 1 MSRAYDLVVIGAGSGGLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGA YMD +RESAGFGWE D SV+ NWK LIAAKN+AV IN SYEGMF DTEGL
Sbjct: 61 KLMVTGANYMDTIRESAGFGWELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
F GWG+L+ + V+VRE+ADP SAV E L ++ILLATGSWPQ I G + CI+SNE
Sbjct: 121 TFHQGWGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQHLGIEGDDLCITSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL E P+R L VGGG+IS+EFAGIFNAYK GG+V L YR ++ILRGFD +R+++T+
Sbjct: 181 AFYLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELRKQLTE 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI + T+ENPAKV+ N DG++HV FESG D DVVM+AIGR+PR+ LQL G
Sbjct: 241 QLRANGINVRTHENPAKVTKNADGTRHVVFESGAEADYDVVMLAIGRVPRSQTLQLDKAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V++ G ++VD +S+TNV NIYAIGD+TDR+MLTPVAINEGAA VDTVF NKPR TDHT
Sbjct: 301 VEVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVFANKPRATDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
+VA AVFSIPP+G CG +EE AAK++++VAVY SSFTPLMHNISGS YKKF+ +IVTNH+
Sbjct: 361 KVACAVFSIPPMGVCGYVEEDAAKKYDQVAVYESSFTPLMHNISGSTYKKFMVRIVTNHA 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DG VLGVH+LGD +PEIIQ+V +CL++ AKISDFYNTIGVHPTSAEELCSMRTP+Y+Y K
Sbjct: 421 DGEVLGVHMLGDSSPEIIQSVAICLKMGAKISDFYNTIGVHPTSAEELCSMRTPAYFYQK 480
Query: 481 GEKMEKL 487
G+++EK+
Sbjct: 481 GKRVEKI 487
>sp|P39040|TYTR_CRIFA Trypanothione reductase (TR) (N(1),N(8)-bis(glutathionyl)spermidine
reductase)
emb|CAA78264.1| trypanothione reductase [Crithidia fasciculata]
Length = 491
Score = 731 bits (1887), Expect = 0.0, Method: Composition-based stats.
Identities = 344/492 (69%), Positives = 412/492 (83%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MS+A+DLVVIGAGSGGLEAGWNAA+L+ KRVAV+D+Q HGPP YAALGGTCVNVGCVPK
Sbjct: 1 MSRAYDLVVIGAGSGGLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGA YMD +RESAGFGWE D SV+ NWK LIAAKN+AV IN SYEGMF DTEGL
Sbjct: 61 KLMVTGANYMDTIRESAGFGWELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
F G+G+L+ + V+VRE+ADP SAV E L ++ILLATGSWPQ I G + CI+SNE
Sbjct: 121 TFHQGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQHLGIEGDDLCITSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL E P+R L VGGG+IS+EFAGIFNAYK GG+V L YR ++ILRGFD +R+++T+
Sbjct: 181 AFYLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELRKQLTE 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI + T+ENPAKV+ N DG++HV FESG D DVVM+AIGR+PR+ LQL G
Sbjct: 241 QLRANGINVRTHENPAKVTKNADGTRHVVFESGAEADYDVVMLAIGRVPRSQTLQLDKAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V++ G ++VD +S+TNV NIYAIGD+TDR+MLTPVAINEGAA VDTVF NKPR TDHT
Sbjct: 301 VEVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVFANKPRATDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
+VA AVFSIPP+G CG +EE AAK++++VAVY SSFTPLMHNISGS YKKF+ +IVTNH+
Sbjct: 361 KVACAVFSIPPMGVCGYVEEDAAKKYDQVAVYESSFTPLMHNISGSTYKKFMVRIVTNHA 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DG VLGVH+LGD +PEIIQ+V +CL++ AKISDFYNTIGVHPTSAEELCSMRTP+Y+Y K
Sbjct: 421 DGEVLGVHMLGDSSPEIIQSVAICLKMGAKISDFYNTIGVHPTSAEELCSMRTPAYFYQK 480
Query: 481 GEKMEKLPDSNL 492
G+++EK+ DSNL
Sbjct: 481 GKRVEKI-DSNL 491
>pdb|1FEA|A Chain A, Unliganded Crithidia Fasciculata Trypanothione Reductase
At 2.2 Angstrom Resolution
pdb|1FEA|B Chain B, Unliganded Crithidia Fasciculata Trypanothione Reductase
At 2.2 Angstrom Resolution
pdb|1FEA|C Chain C, Unliganded Crithidia Fasciculata Trypanothione Reductase
At 2.2 Angstrom Resolution
pdb|1FEA|D Chain D, Unliganded Crithidia Fasciculata Trypanothione Reductase
At 2.2 Angstrom Resolution
pdb|1FEB|A Chain A, Unliganded Crithidia Fasciculata Trypanothione Reductase
At 2.0 Angstrom Resolution
pdb|1FEB|B Chain B, Unliganded Crithidia Fasciculata Trypanothione Reductase
At 2.0 Angstrom Resolution
pdb|1FEC|A Chain A, Unliganded Crithidia Fasciculata Trypanothione Reductase
At 1.7 Angstrom Resolution
pdb|1FEC|B Chain B, Unliganded Crithidia Fasciculata Trypanothione Reductase
At 1.7 Angstrom Resolution
Length = 490
Score = 728 bits (1878), Expect = 0.0, Method: Composition-based stats.
Identities = 343/491 (69%), Positives = 411/491 (83%), Gaps = 1/491 (0%)
Query: 2 SKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKK 61
S+A+DLVVIGAGSGGLEAGWNAA+L+ KRVAV+D+Q HGPP YAALGGTCVNVGCVPKK
Sbjct: 1 SRAYDLVVIGAGSGGLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCVNVGCVPKK 60
Query: 62 LMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLD 121
LMVTGA YMD +RESAGFGWE D SV+ NWK LIAAKN+AV IN SYEGMF DTEGL
Sbjct: 61 LMVTGANYMDTIRESAGFGWELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADTEGLT 120
Query: 122 FFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEA 181
F G+G+L+ + V+VRE+ADP SAV E L ++ILLATGSWPQ I G + CI+SNEA
Sbjct: 121 FHQGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQHLGIEGDDLCITSNEA 180
Query: 182 FYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQ 241
FYL E P+R L VGGG+IS+EFAGIFNAYK GG+V L YR ++ILRGFD +R+++T+Q
Sbjct: 181 FYLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELRKQLTEQ 240
Query: 242 LTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGV 301
L ANGI + T+ENPAKV+ N DG++HV FESG D DVVM+AIGR+PR+ LQL GV
Sbjct: 241 LRANGINVRTHENPAKVTKNADGTRHVVFESGAEADYDVVMLAIGRVPRSQTLQLEKAGV 300
Query: 302 KLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTR 361
++ G ++VD +S+TNV NIYAIGD+TDR+MLTPVAINEGAA VDTVF NKPR TDHT+
Sbjct: 301 EVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVFANKPRATDHTK 360
Query: 362 VASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSD 421
VA AVFSIPP+G CG +EE AAK++++VAVY SSFTPLMHNISGS YKKF+ +IVTNH+D
Sbjct: 361 VACAVFSIPPMGVCGYVEEDAAKKYDQVAVYESSFTPLMHNISGSTYKKFMVRIVTNHAD 420
Query: 422 GTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKG 481
G VLGVH+LGD +PEIIQ+V +CL++ AKISDFYNTIGVHPTSAEELCSMRTP+Y+Y KG
Sbjct: 421 GEVLGVHMLGDSSPEIIQSVAICLKMGAKISDFYNTIGVHPTSAEELCSMRTPAYFYEKG 480
Query: 482 EKMEKLPDSNL 492
+++EK+ DSNL
Sbjct: 481 KRVEKI-DSNL 490
>pdb|1TYT|A Chain A, Crystal And Molecular Structure Of Crithidia Fasciculata
Trypanothione Reductase At 2.6 Angstroms Resolution
pdb|1TYT|B Chain B, Crystal And Molecular Structure Of Crithidia Fasciculata
Trypanothione Reductase At 2.6 Angstroms Resolution
Length = 487
Score = 727 bits (1877), Expect = 0.0, Method: Composition-based stats.
Identities = 340/487 (69%), Positives = 408/487 (83%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MS+A+DLVVIGAGSGGLEAGWNAA+L+ KRVAV+D+Q HGPP YAALGGTCVNVGCVPK
Sbjct: 1 MSRAYDLVVIGAGSGGLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGA YMD +RESAGFGWE D SV+ NWK LIAAKN+AV IN SYEGMF DTEGL
Sbjct: 61 KLMVTGANYMDTIRESAGFGWELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
F G+G+L+ + V+VRE+ADP SAV E L ++ILLATGSWPQ I G + CI+SNE
Sbjct: 121 TFHQGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQHLGIEGDDLCITSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL E P+R L VGGG+IS+EFAGIFNAYK GG+V L YR ++ILRGFD +R+++T+
Sbjct: 181 AFYLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELRKQLTE 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI + T+ENPAKV+ N DG++HV FESG D DVVM+AIGR+PR+ LQL G
Sbjct: 241 QLRANGINVRTHENPAKVTKNADGTRHVVFESGAEADYDVVMLAIGRVPRSQTLQLDKAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V++ G ++VD +S+TNV NIYAIGD+TDR+MLTPVAINEGAA VDTVF NKPR TDHT
Sbjct: 301 VEVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVFANKPRATDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
+VA AVFSIPP+G CG +EE AAK++++VAVY SSFTPLMHNISGS YKKF+ +IVTNH+
Sbjct: 361 KVACAVFSIPPMGVCGYVEEDAAKKYDQVAVYESSFTPLMHNISGSTYKKFMVRIVTNHA 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DG VLGVH+LGD +PEIIQ+V +CL++ AKISDFYNTIGVHPTSAEELCSMRTP+Y+Y K
Sbjct: 421 DGEVLGVHMLGDSSPEIIQSVAICLKMGAKISDFYNTIGVHPTSAEELCSMRTPAYFYQK 480
Query: 481 GEKMEKL 487
G+++EK+
Sbjct: 481 GKRVEKI 487
>gb|AAA30322.1| trypanothione reductase
Length = 491
Score = 725 bits (1871), Expect = 0.0, Method: Composition-based stats.
Identities = 342/492 (69%), Positives = 410/492 (83%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MS+A+DLVVIGAGSG LEAGWNAA+L+ KRVAV+D+Q HGPP YAALGGTCVNVGCVPK
Sbjct: 1 MSRAYDLVVIGAGSGRLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGA YMD +RESAGFGWE D SV+ NWK LIAAKN+AV IN SYEGMF DTEGL
Sbjct: 61 KLMVTGANYMDTIRESAGFGWELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
F G+G+L+ + V+VRE+ADP SAV E L ++ILLATGSWPQ I G + CI+SNE
Sbjct: 121 TFHQGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQHLGIEGDDLCITSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL E P+R L VGGG+IS+EFAGIFNAYK GG+V L YR ++ILRGFD +R+++T+
Sbjct: 181 AFYLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELRKQLTE 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI + T+ENPAKV+ N DG++HV FESG D DVVM+AIGR+PR+ LQL G
Sbjct: 241 QLRANGINVRTHENPAKVTKNADGTRHVVFESGAEADYDVVMLAIGRVPRSQTLQLEKAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V++ G ++VD +S+TNV NIYAIGD+TDR+MLTPVAINEGAA VDTVF NKPR TDHT
Sbjct: 301 VEVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVFANKPRATDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
+VA AVFSIPP+G CG +EE AAK++++VAVY SSFTPLMHNISGS YKKF+ +IVTNH+
Sbjct: 361 KVACAVFSIPPMGVCGYVEEDAAKKYDQVAVYESSFTPLMHNISGSTYKKFMVRIVTNHA 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DG VLGVH+LGD +PEIIQ+V +CL++ AKISD YNTIGVHPTSAEELCSMRTP+Y+Y K
Sbjct: 421 DGEVLGVHMLGDSSPEIIQSVAICLKMGAKISDVYNTIGVHPTSAEELCSMRTPAYFYQK 480
Query: 481 GEKMEKLPDSNL 492
G+++EK+ DSNL
Sbjct: 481 GKRVEKI-DSNL 491
>gb|AAA30323.1| trypanothione reductase
Length = 491
Score = 724 bits (1870), Expect = 0.0, Method: Composition-based stats.
Identities = 342/492 (69%), Positives = 410/492 (83%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MS+A+DLVVIGAGSG LEAGWNAA+L+ KRVAV+D+Q HGPP YAALGGTCVNVGCVPK
Sbjct: 1 MSRAYDLVVIGAGSGRLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGA YMD +RESAGFGWE D SV+ NWK LIAAKN+AV IN SYEGMF DTEGL
Sbjct: 61 KLMVTGANYMDTIRESAGFGWELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
F G+G+L+ + V+VRE+ADP SAV E L ++ILLATGSWPQ I G + CI+SNE
Sbjct: 121 TFHQGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQHLGIEGDDLCITSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL E P+R L VGGG+IS+EFAGIFNAYK GG+V L YR ++ILRGFD +R+++T+
Sbjct: 181 AFYLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELRKQLTE 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI + T+ENPAKV+ N DG++HV FESG D DVVM+AIGR+PR+ LQL G
Sbjct: 241 QLRANGINVRTHENPAKVTKNADGTRHVVFESGAEADYDVVMLAIGRVPRSQTLQLEKAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V++ G ++VD +S+TNV NIYAIGD+TDR+MLTPVAINEGAA VDTVF NKPR TDHT
Sbjct: 301 VEVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVFANKPRATDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
+VA AVFSIPP+G CG +EE AAK++++VAVY SSFTPLMHNISGS YKKF+ +IVTNH+
Sbjct: 361 KVACAVFSIPPMGVCGYVEEDAAKKYDQVAVYESSFTPLMHNISGSTYKKFMVRIVTNHA 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DG VLGVH+LGD +PEIIQ+V +CL++ AKISD YNTIGVHPTSAEELCSMRTP+Y+Y K
Sbjct: 421 DGEVLGVHMLGDSSPEIIQSVAICLKMGAKISDVYNTIGVHPTSAEELCSMRTPAYFYEK 480
Query: 481 GEKMEKLPDSNL 492
G+++EK+ DSNL
Sbjct: 481 GKRVEKI-DSNL 491
>pdb|2TPR|A Chain A, X-Ray Structure Of Trypanothione Reductase From Crithidia
Fasciculata At 2.4 Angstroms Resolution
pdb|2TPR|B Chain B, X-Ray Structure Of Trypanothione Reductase From Crithidia
Fasciculata At 2.4 Angstroms Resolution
Length = 490
Score = 724 bits (1870), Expect = 0.0, Method: Composition-based stats.
Identities = 342/491 (69%), Positives = 410/491 (83%), Gaps = 1/491 (0%)
Query: 2 SKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKK 61
S+A+DLVVIGAGSGGLEAGWNAA+L+ KRVAV+D+Q HGPP YAALGGTCVNVGCVPKK
Sbjct: 1 SRAYDLVVIGAGSGGLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCVNVGCVPKK 60
Query: 62 LMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLD 121
LMVTGA YMD +RESAGFGWE D SV+ NWK LIAAKN+AV IN SYEGMF DTEGL
Sbjct: 61 LMVTGANYMDTIRESAGFGWELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADTEGLT 120
Query: 122 FFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEA 181
F G+G+L+ + V+VRE+ADP SAV E L ++ILLATGSWPQ I G + CI+SNEA
Sbjct: 121 FHQGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQHLGIEGDDLCITSNEA 180
Query: 182 FYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQ 241
FYL E P+R L VGGG+IS+EFAGIFNAYK GG+V L YR ++ILRGFD +R+++T+Q
Sbjct: 181 FYLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELRKQLTEQ 240
Query: 242 LTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGV 301
L ANGI + T+ENPAKV+ N DG++HV FESG D DVVM+AIGR+PR+ LQL GV
Sbjct: 241 LRANGINVRTHENPAKVTKNADGTRHVVFESGAEADYDVVMLAIGRVPRSQTLQLEKAGV 300
Query: 302 KLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTR 361
++ G ++VD +S+TNV NIYAIGD+TDR+MLTPVAINEGAA VDTVF NKPR TDHT+
Sbjct: 301 EVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVFANKPRATDHTK 360
Query: 362 VASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSD 421
VA AVFSIPP+G CG +EE AAK++++VAVY SSFTPLMHNISGS YKKF+ +IVTNH+D
Sbjct: 361 VACAVFSIPPMGVCGYVEEDAAKKYDQVAVYESSFTPLMHNISGSTYKKFMVRIVTNHAD 420
Query: 422 GTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKG 481
G VLGVH+LGD +PEIIQ+V +CL++ AKISD YNTIGVHPTSAEELCSMRTP+Y+Y KG
Sbjct: 421 GEVLGVHMLGDSSPEIIQSVAICLKMGAKISDVYNTIGVHPTSAEELCSMRTPAYFYEKG 480
Query: 482 EKMEKLPDSNL 492
+++EK+ DSNL
Sbjct: 481 KRVEKI-DSNL 490
>ref|XP_001561849.1| trypanothione reductase [Leishmania braziliensis MHOM/BR/75/M2904]
emb|CAM36869.1| trypanothione reductase [Leishmania braziliensis]
Length = 491
Score = 708 bits (1827), Expect = 0.0, Method: Composition-based stats.
Identities = 332/487 (68%), Positives = 400/487 (82%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
M +A+DLVV+GAGSGGLEAGWNAA++Y K+VAVV+ Q HGPP +AALGGTCVNVGCVPK
Sbjct: 1 MPRAYDLVVLGAGSGGLEAGWNAASIYNKKVAVVEAQKEHGPPCFAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMD +RES GFGWE D S+++NWKKLI AKN+ V DINKSY MF +TEGL
Sbjct: 61 KLMVTGAQYMDLIRESCGFGWEMDRDSIRSNWKKLITAKNKVVSDINKSYTDMFENTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
F +G+G+L+ + VVVR++ DP+S V E L+AD+IL+ATGSWP IPG E CI+SNE
Sbjct: 121 SFHMGFGALQDAHTVVVRKSEDPESDVLETLEADYILIATGSWPTRLGIPGDELCITSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL E P+R L VGGG+ISVEFAGIFNAYKPP G+V LCYR +ILRGFD +R+ + K
Sbjct: 181 AFYLDEAPKRALCVGGGYISVEFAGIFNAYKPPDGQVDLCYRGEVILRGFDLEVRKSLMK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI+I T NP++++ N DGSKHV FE G D D VM+A+GR PR+ LQL G
Sbjct: 241 QLEANGIKIRTKVNPSRITKNADGSKHVCFEDGTEADYDQVMLAVGRAPRSKALQLDKAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
VK+ G V VD +S+T+V NIYAIGD+TDRLMLTPVAINEG+A V+T+FG KPR TDHT
Sbjct: 301 VKMGKNGAVVVDAYSKTSVDNIYAIGDVTDRLMLTPVAINEGSAFVETLFGCKPRATDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
+VA AVFSIPPIGTCGL EE AAK+++ VAVY SSFTPLMHNISGSK+K F+ +IVT
Sbjct: 361 KVACAVFSIPPIGTCGLTEEEAAKKYDVVAVYESSFTPLMHNISGSKHKTFMIRIVTKEK 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
DG VLGVH+LGD APEIIQ+VG+C+R+ AKISDF++TIGVHPTSAEELCSMRTP+Y+Y K
Sbjct: 421 DGEVLGVHMLGDSAPEIIQSVGICMRMGAKISDFHSTIGVHPTSAEELCSMRTPAYFYEK 480
Query: 481 GEKMEKL 487
G+++EKL
Sbjct: 481 GKRVEKL 487
>ref|XP_001462998.1| trypanothione reductase [Leishmania infantum]
emb|CAM65344.1| trypanothione reductase [Leishmania infantum]
Length = 491
Score = 694 bits (1791), Expect = 0.0, Method: Composition-based stats.
Identities = 330/492 (67%), Positives = 399/492 (81%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MS+A+DLVV+GAGSGGLEAGWNAA + K+VAVVDVQ +HGPP +AALGGTCVNVGCVPK
Sbjct: 1 MSRAYDLVVLGAGSGGLEAGWNAAVTHKKKVAVVDVQATHGPPLFAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMD +RES GFGWE D S+ NWK LIAAKN+ V IN+SY+ MF DTEGL
Sbjct: 61 KLMVTGAQYMDLIRESGGFGWEMDRESLCPNWKTLIAAKNKVVNSINESYKSMFADTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
F +G+G+L+ + VVVR++ DP S V E L ++IL+ATGSWP +PG E CI+SNE
Sbjct: 121 SFHMGFGALQDAHTVVVRKSEDPHSDVLETLDTEYILIATGSWPTRLGVPGDEFCITSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL + P+R+L VGGG+I+VEFAGIFN YKP GG V LCYR +LILRGFD +R+ +TK
Sbjct: 181 AFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKPCGGYVDLCYRGDLILRGFDTEVRKSLTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI + TN NP K++ N DGS HV F G D D VM+AIGR+PR+ LQL G
Sbjct: 241 QLGANGIRVRTNLNPTKITKNEDGSNHVHFNDGTEEDYDQVMLAIGRVPRSQALQLDKAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V+ G VQVD +S+T+V NIYAIGD+T+R+MLTPVAINEGAA V+TVFG KPR TDHT
Sbjct: 301 VRTGKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINEGAAFVETVFGGKPRATDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
+VA AVFSIPPIGTCG+ EE AAK +E VAVY SSFTPLMHNISGSK+K+F+ +I+TN S
Sbjct: 361 KVACAVFSIPPIGTCGMTEEEAAKNYETVAVYASSFTPLMHNISGSKHKEFMIRIITNES 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
+G VLGVH+LGD APEIIQ+VG+C+++ AKISDF++TIGVHPTSAEELCSMRTP+Y+Y
Sbjct: 421 NGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHSTIGVHPTSAEELCSMRTPAYFYES 480
Query: 481 GEKMEKLPDSNL 492
G+++EKL SNL
Sbjct: 481 GKRVEKL-SSNL 491
>ref|XP_001687512.1| trypanothione reductase [Leishmania major]
emb|CAJ01955.1| trypanothione reductase [Leishmania major]
Length = 491
Score = 689 bits (1778), Expect = 0.0, Method: Composition-based stats.
Identities = 327/492 (66%), Positives = 395/492 (80%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MS+A+DLVV+GAGSGGLEAGWNAA Y K+VAVVDVQ +HGPPF+AALGGTCVNVGCVPK
Sbjct: 1 MSRAYDLVVLGAGSGGLEAGWNAAATYKKKVAVVDVQATHGPPFFAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMD +RES GFGWE + S+ NWK LIAAKN+ V IN+SY+ MF DTEGL
Sbjct: 61 KLMVTGAQYMDLIRESGGFGWEMNRESLCPNWKTLIAAKNKVVNGINESYKSMFADTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
F +G+G+L+ + V+VR++ DP S V E L ++IL+ATGSWP +PG E CI+SNE
Sbjct: 121 SFHMGFGALQDAHTVLVRKSEDPNSDVLETLDTEYILIATGSWPTRLGVPGDEFCITSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL + P+R+L VGGG+I+VEFAGIFN YKP GG V LCYR +LILRGFD +R+ +TK
Sbjct: 181 AFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKPRGGYVDLCYRGDLILRGFDTEVRKSLTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI + TN NP K++ N DGS HV F G D D VM+AIGR+PR+ LQL G
Sbjct: 241 QLGANGIRVRTNLNPTKITKNEDGSNHVHFNDGTEEDYDQVMLAIGRVPRSQTLQLDKAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V+ G VQVD +S+T+V NIYAIGD+T+R+MLTPVAINEGAA +TVFG KPR TDHT
Sbjct: 301 VQTAKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINEGAAFAETVFGGKPRATDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
+VA AVFSIPPIGTCG+ EE AAK E VAVY S FTPLMHNISGSK+K+F+ +I+T+
Sbjct: 361 KVACAVFSIPPIGTCGMTEEEAAKNHETVAVYESCFTPLMHNISGSKHKEFMIRIITDQP 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
G VLGVH+LGD APEIIQ+VG+C+++ AKISDF+NTIGVHPTSAEELCSMRTP+Y+Y
Sbjct: 421 SGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHNTIGVHPTSAEELCSMRTPAYFYEN 480
Query: 481 GEKMEKLPDSNL 492
G+++EKL SNL
Sbjct: 481 GKRVEKL-SSNL 491
>gb|ABQ57410.1| trypanothione reductase [Leishmania amazonensis]
Length = 491
Score = 679 bits (1753), Expect = 0.0, Method: Composition-based stats.
Identities = 324/492 (65%), Positives = 396/492 (80%), Gaps = 1/492 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MS+A+D VV+GAGSGGLEAGWNAA Y K+VAV+DVQ +HGPPF+AALGGTCVNVGCVPK
Sbjct: 1 MSRAYDPVVLGAGSGGLEAGWNAAVTYKKKVAVIDVQATHGPPFFAALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMD +RES GFGWE + S+ NWK LIAAKN+ V IN+SY+ MF DTEGL
Sbjct: 61 KLMVTGAQYMDLIRESGGFGWEMNRESLCPNWKTLIAAKNKVVNGINESYKSMFADTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
F +G+G+L+ + V+VR++ DP S V E L ++IL+ATGSWP +PG E CI+SNE
Sbjct: 121 SFHMGFGALQDAHTVLVRKSEDPNSDVLETLDTEYILIATGSWPTRLGVPGDEFCITSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL + P+R+L VGGG+I+VEFAGIFN YKP GG V LCYR + ILRGFD +R+ +TK
Sbjct: 181 AFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKPRGGYVDLCYRGDPILRGFDTEVRKSLTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI + TN NP K++ N DGS HV F G D D VM+AIGR+PR+ LQL VG
Sbjct: 241 QLGANGIRVRTNLNPTKITKNEDGSNHVHFNDGTEEDYDQVMLAIGRVPRSQALQLDKVG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V+ G VQVD +S+T+V NIYAIGD+T+R+MLTPVAINEGAA V+TVFG KPR TDHT
Sbjct: 301 VQTGKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINEGAAFVETVFGGKPRATDHT 360
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHS 420
+VA AV SIPPIGTCG+ EE AAK+ E VAVY S FTPLM+NISGSK+K+F+ +I+TN
Sbjct: 361 KVACAVSSIPPIGTCGMTEEAAAKDHETVAVYESCFTPLMYNISGSKHKEFMIRIITNQP 420
Query: 421 DGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVK 480
G VLGVH+LGD APEIIQ+VG+C+++ AKISDF++TIGVHPTSAEELCSMRTP+Y+Y +
Sbjct: 421 TGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHSTIGVHPTSAEELCSMRTPAYFYER 480
Query: 481 GEKMEKLPDSNL 492
G+++EKL SNL
Sbjct: 481 GKRVEKL-SSNL 491
>sp|P39050|TYTR_LEIDO Trypanothione reductase (TR) (N(1),N(8)-bis(glutathionyl)spermidine
reductase)
emb|CAA80668.1| trypanothione reductase [Leishmania donovani]
Length = 491
Score = 677 bits (1747), Expect = 0.0, Method: Composition-based stats.
Identities = 327/493 (66%), Positives = 396/493 (80%), Gaps = 3/493 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MS+A+DLVV+GAGSGGLEAGWNAA + K+VAVVDVQ +HGPP ALGGTCVNVGCVPK
Sbjct: 1 MSRAYDLVVLGAGSGGLEAGWNAAVTHKKKVAVVDVQATHGPPALVALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMD +RES GFGWE D S+ NWK LIAAKN+ V IN+SY+ MF DTEGL
Sbjct: 61 KLMVTGAQYMDLIRESGGFGWEMDRESLCPNWKTLIAAKNKVVNSINESYKSMFADTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
F +G+G+L+ + VVVR++ DP S V E L ++IL+ATGSWP +PG E CI+SNE
Sbjct: 121 SFHMGFGALQDAHTVVVRKSEDPHSDVLETLDTEYILIATGSWPTRLGVPGDEFCITSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYL + P+R+L VGGG+I+VEFAGIFN YKP GG V LCYR +LILRGFD +R+ +TK
Sbjct: 181 AFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKPCGGYVDLCYRGDLILRGFDTEVRKSLTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QL ANGI + TN NP K++ N DGS HV F G D D VM+AIG +PR+ LQL G
Sbjct: 241 QLGANGIRVRTNLNPTKITKNEDGSNHVHFNDGTEEDYDQVMLAIG-VPRSQALQLDKAG 299
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGA-ALVDTVFGNKPRKTDH 359
V+ G VQVD +S+T+V NIYAIGD+T+R+MLTPVAINEGA L++TVFG KPR TDH
Sbjct: 300 VRTGKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINEGACVLLETVFGGKPRATDH 359
Query: 360 TRVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNH 419
T+VA AVFSIPPIGTCG+ EE AAK +E VAVY SSFTPLMHNISGSK+K+F+ +I+TN
Sbjct: 360 TKVACAVFSIPPIGTCGMTEEEAAKNYETVAVYASSFTPLMHNISGSKHKEFMIRIITNE 419
Query: 420 SDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYV 479
S+G VLGVH+LGD APEIIQ+VG+C+++ AKISDF++TIGVHPTSAEELCSMRTP+Y+Y
Sbjct: 420 SNGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHSTIGVHPTSAEELCSMRTPAYFYE 479
Query: 480 KGEKMEKLPDSNL 492
G+++EKL SNL
Sbjct: 480 SGKRVEKL-SSNL 491
>ref|XP_803005.1| trypanothione reductase, putative [Trypanosoma cruzi strain CL
Brener]
gb|EAN81559.1| trypanothione reductase, putative [Trypanosoma cruzi]
Length = 388
Score = 668 bits (1723), Expect = 0.0, Method: Composition-based stats.
Identities = 318/389 (81%), Positives = 349/389 (89%), Gaps = 1/389 (0%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MSK FDLVVIGAGSGGLEA WNAATLY KRVAV+DVQ HGPPF++ALGGTCVNVGCVPK
Sbjct: 1 MSKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPK 60
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYM+HLRESAGFGWEFD ++++A WKKLIA K+EAVL+INKSYE MF DTEGL
Sbjct: 61 KLMVTGAQYMEHLRESAGFGWEFDRTTLRAEWKKLIAVKDEAVLNINKSYEEMFRDTEGL 120
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
+FFLGWGSLESKNVV VRE+ADP SAVKERL+ +HILLA+GSWP MP IPGIEHCISSNE
Sbjct: 121 EFFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIEHCISSNE 180
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKP G+VTLCYR +ILRGFD T+REE+TK
Sbjct: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREELTK 240
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
QLTANGI+I+T ENPAKV LN DGSK VTFESGK +D D+VMMAIGR PRT DLQL N G
Sbjct: 241 QLTANGIQILTKENPAKVELNADGSKSVTFESGKKMDFDLVMMAIGRSPRTKDLQLQNAG 300
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHT 360
V + GGVQVDE+SRTNV NIYAIGD+T+R+MLTPVAINE AALVDT+FG PRKTDHT
Sbjct: 301 V-MIKNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTIFGTTPRKTDHT 359
Query: 361 RVASAVFSIPPIGTCGLIEEVAAKEFEKV 389
RVASAVFSIPPIGTCGLIEEVA+K +E V
Sbjct: 360 RVASAVFSIPPIGTCGLIEEVASKRYEVV 388
>gb|ABF74601.1| trypanothione reductase [Leishmania amazonensis]
Length = 476
Score = 650 bits (1678), Expect = 0.0, Method: Composition-based stats.
Identities = 310/476 (65%), Positives = 375/476 (78%)
Query: 8 VVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMVTGA 67
VV+GAGSGGLEAGWNAA + K+VAVVD+Q HGPP +AALGGTCVNVGCVPKKLMVTGA
Sbjct: 1 VVLGAGSGGLEAGWNAAVTHKKKVAVVDLQAVHGPPLFAALGGTCVNVGCVPKKLMVTGA 60
Query: 68 QYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFLGWG 127
QYMD LRES GFGWE S+ NWK LIAAKN+ V IN+SY+ MF +TEGL F +G+G
Sbjct: 61 QYMDTLRESGGFGWEMSRESLCPNWKTLIAAKNKVVSGINESYKKMFAETEGLSFHMGFG 120
Query: 128 SLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYLPEP 187
+ + + VVVR++ D S V E L ++IL+ATGSWP IPG E CI+SNEAFYL +
Sbjct: 121 AFQDAHTVVVRKSEDQNSDVLETLDTEYILIATGSWPTRLGIPGDELCITSNEAFYLEDA 180
Query: 188 PRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGI 247
P+R L VGGG+I+VEFAGIFN YKP GG V LCYR ++ILRGFD +R+ +TKQL ANGI
Sbjct: 181 PKRTLCVGGGYIAVEFAGIFNGYKPRGGIVDLCYRGDVILRGFDLEVRKSLTKQLEANGI 240
Query: 248 EIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKG 307
++ T +P K++ N DGSKHV F G D D VM+AIGR+PR+ LQL GVK
Sbjct: 241 QVRTKLSPTKITKNEDGSKHVHFNDGTEADYDQVMLAIGRVPRSQALQLDKAGVKTGKND 300
Query: 308 GVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVASAVF 367
V VD +S+T++ NIYAIGD+T R+MLTPVAINEGAA V+TVF KP TDHT+VA A+F
Sbjct: 301 AVLVDAYSKTSMDNIYAIGDVTSRVMLTPVAINEGAAFVETVFAGKPSATDHTKVACAIF 360
Query: 368 SIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTVLGV 427
SIPPIGTCGL EE AAK +E VAVY +SFTPLMHNISGSKYK+F+ +I+TN SDG VLGV
Sbjct: 361 SIPPIGTCGLTEEEAAKIYETVAVYENSFTPLMHNISGSKYKEFMVRIITNESDGEVLGV 420
Query: 428 HLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTPSYYYVKGEK 483
H+LG+ APEIIQ+VG+C+++ AKISDF+NTIGVHPTSAEELCSMR P+Y+Y G++
Sbjct: 421 HMLGESAPEIIQSVGICMKMGAKISDFHNTIGVHPTSAEELCSMRAPAYFYENGKR 476
>emb|CAC94295.1| trypanothione reductase [Leishmania donovani donovani]
Length = 491
Score = 577 bits (1488), Expect = e-163, Method: Composition-based stats.
Identities = 294/501 (58%), Positives = 363/501 (72%), Gaps = 19/501 (3%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MS+A+DLVV+GAGSGGLEAGWN A + K+V + ++LGGTCVNVGCVPK
Sbjct: 1 MSRAYDLVVLGAGSGGLEAGWNPAVTHKKKVGPSSM-CRRRTVRRSSLGGTCVNVGCVPK 59
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KLMVTGAQYMD +RES GFGWE D S+ +WK LIAAKN+ V I +SY+ MF DTEGL
Sbjct: 60 KLMVTGAQYMDLIRESGGFGWEMDRESLCPHWKTLIAAKNKVVNSIYESYKSMFADTEGL 119
Query: 121 DFFLGWGSLES--KNVVVVRETA-----DPKSAVKERLQADHILLATGSWPQMPAIPGIE 173
F +G+G++ + + R+T DP+ + H LLA P+ P +
Sbjct: 120 SFHMGFGAINTLTRWWCASRKTHTATCWDPRHGLHPHC---HRLLADA--PRSPRRRVLH 174
Query: 174 HCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDET 233
H FYL + P+R+L VGG +I+VEFAGIFN YKP GG V LCYR +LILRGFD
Sbjct: 175 H---EQRGFYLEDAPKRMLCVGGCYIAVEFAGIFNGYKPQGGYVDLCYRGDLILRGFDTE 231
Query: 234 IREEVTKQLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTND 293
+R+ +TKQL ANGI + TN NP K++ N DGS HV F G D D VM+AIGR+PR+
Sbjct: 232 VRKSLTKQLGANGIRVRTNLNPTKITKNEDGSNHVHFNDGTEEDYDQVMLAIGRVPRSQA 291
Query: 294 LQLGNVGVKLTPKGGVQVDEFSRTNVPNIYAI--GDITDRLMLTPVAINEGAALVDTVFG 351
LQL GV+ G VQVD +S+T+V NIYAI GD+T+R+MLTPVAINEGAA V+TVFG
Sbjct: 292 LQLAKAGVRTGKNGAVQVDAYSKTSVDNIYAIAIGDVTNRVMLTPVAINEGAAFVETVFG 351
Query: 352 NKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKF 411
KPR TDH +VA VFSIPPIGTCG+ EE AAK +E VAVY SSFTPLMHNISGSK+K+F
Sbjct: 352 GKPRATDHRKVACRVFSIPPIGTCGMTEEEAAKNYETVAVYASSFTPLMHNISGSKHKEF 411
Query: 412 VAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSM 471
+I+TN S+G VLGVH+LGD APEIIQ+VG+C+++ AKIS F++TIGVHPTSAEELCSM
Sbjct: 412 TIRIITNESNGEVLGVHMLGDSAPEIIQSVGICMQMGAKISGFHSTIGVHPTSAEELCSM 471
Query: 472 RTPSYYYVKGEKMEKLPDSNL 492
RTP+Y+Y G+++EKL SNL
Sbjct: 472 RTPAYFYESGKRVEKL-SSNL 491
>gb|AAA30321.1| trypanothione reductase
Length = 394
Score = 559 bits (1440), Expect = e-157, Method: Composition-based stats.
Identities = 264/394 (67%), Positives = 320/394 (81%)
Query: 59 PKKLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTE 118
PKKLMVTGA YMD +RESAGFGWE D SV+ NWK LIAAKN+AV IN SYEGMF DTE
Sbjct: 1 PKKLMVTGANYMDTIRESAGFGWELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADTE 60
Query: 119 GLDFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISS 178
GL F G+G+L+ + V+VRE+ADP SAV E L ++ILLATGSWPQ I G + CI+S
Sbjct: 61 GLTFHQGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQHLGIEGDDLCITS 120
Query: 179 NEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEV 238
NEAFYL E P+R L VGGG+IS+EFAGIFNAYK GG+V L YR ++ILRGFD +R+++
Sbjct: 121 NEAFYLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELRKQL 180
Query: 239 TKQLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGN 298
T+QL ANGI + T+ENPAKV+ N DG++HV FESG D DVVM+AIGR+PR+ LQL
Sbjct: 181 TEQLRANGINVRTHENPAKVTKNADGTRHVVFESGAEADYDVVMLAIGRVPRSQTLQLEK 240
Query: 299 VGVKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTD 358
GV++ G ++VD +S+TNV NIYAIGD+TDR+MLTPVAINEGAA VDTVF NKPR TD
Sbjct: 241 AGVEVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVFANKPRATD 300
Query: 359 HTRVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTN 418
HT+VA AVFSIPP+G CG +EE AAK++++VAVY SSFTPLMHNISGS YKKF+ +IVTN
Sbjct: 301 HTKVACAVFSIPPMGVCGYVEEDAAKKYDQVAVYESSFTPLMHNISGSTYKKFMVRIVTN 360
Query: 419 HSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKIS 452
H+DG VLGVH+LGD +PEIIQ+V +CL++ AKIS
Sbjct: 361 HADGEVLGVHMLGDSSPEIIQSVAICLKMGAKIS 394
>gb|AAM28598.1| putative trypanothione reductase [Entamoeba histolytica]
Length = 394
Score = 445 bits (1144), Expect = e-123, Method: Composition-based stats.
Identities = 255/412 (61%), Positives = 298/412 (72%), Gaps = 18/412 (4%)
Query: 52 CVNVGCVPKKLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYE 111
CVNVGCVP K ++ QY+ + RESA G+EFD SS +A + LIA + AVL+INKSY+
Sbjct: 1 CVNVGCVPGKYLLF--QYLSYNRESALMGYEFDRSSFRAEVQNLIALLSVAVLNINKSYD 58
Query: 112 GMFNDTEGLDFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPG 171
MF +T G+ LG L KN V VRE+AD S V RL+ I LA+GS+P M IPG
Sbjct: 59 EMFRETRGVKR-LGAPILNVKNTVHVRESADVASLVLFRLETLFIFLASGSFPHMLNIPG 117
Query: 172 IEHCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFD 231
+E CISS+E+F LP+PPRRVL VGGG+ISVEFAGIFNAYKP GG VTLCYRN LILRGFD
Sbjct: 118 LEECISSDESFELPDPPRRVLVVGGGYISVEFAGIFNAYKPEGGNVTLCYRNELILRGFD 177
Query: 232 ETIREEVTKQLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRT 291
T+REE+TK+LTANGI+ T + P KVSLNTDGS+ V FESG+ +D D + MAIGRIP T
Sbjct: 178 LTLREELTKELTANGIQSYTKDFPNKVSLNTDGSESV-FESGRKMDYDCIFMAIGRIPFT 236
Query: 292 NDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFG 351
DLQL N V L KG +QVDEFS T + NI AIGD+T L LTPVAIN ALV TVFG
Sbjct: 237 KDLQLNNAQV-LIDKGLIQVDEFS-TTIANIEAIGDLTTSLELTPVAIN-FRALVHTVFG 293
Query: 352 NKPRKTDHTRVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKF 411
+ PRKTD + V S+VFSIP IG GLI EVA K F+ VAVY SSF L NI+GSKY
Sbjct: 294 STPRKTDLS-VHSSVFSIPNIGLVGLISEVAHKRFKVVAVYESSFRNLKTNITGSKYS-- 350
Query: 412 VAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPT 463
TNHS +LGVH LG GAPEIIQ G+ ++LNAKI+DF TIGVHPT
Sbjct: 351 -----TNHSFIRILGVHNLGLGAPEIIQ--GINVKLNAKIADFL-TIGVHPT 394
>ref|YP_001187841.1| glutathione reductase [Pseudomonas mendocina ymp]
gb|ABP85109.1| NADPH-glutathione reductase [Pseudomonas mendocina ymp]
Length = 452
Score = 362 bits (930), Expect = 3e-98, Method: Composition-based stats.
Identities = 203/477 (42%), Positives = 284/477 (59%), Gaps = 31/477 (6%)
Query: 1 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPK 60
MS FDL VIGAGSGG+ A AA YG RVAV + + LGGTCVNVGCVPK
Sbjct: 1 MSYDFDLFVIGAGSGGVRAARFAAG-YGARVAVAESRY---------LGGTCVNVGCVPK 50
Query: 61 KLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGL 120
KL+V GA + + ++AGFGW +S +W LIA KN + +N Y + ++ G+
Sbjct: 51 KLLVYGAHFSEDFEQAAGFGWSLGEASF--DWPTLIANKNREIQRLNGIYRNLLTNS-GV 107
Query: 121 DFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNE 180
F G + + V V +R A+ IL+ATG WPQ+P IPG EH ISSNE
Sbjct: 108 TLFEGHARIVDAHTVEVN---------GQRHSAERILIATGGWPQIPDIPGREHAISSNE 158
Query: 181 AFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTK 240
AF+L + P+RVL VGGG+I+VEFA IF+ G + +L YR L LRGFD +RE +
Sbjct: 159 AFFLEQLPKRVLVVGGGYIAVEFASIFHGL---GAQTSLLYRGELFLRGFDGAVREHLRD 215
Query: 241 QLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVG 300
+L+ G+++ N + A++ DGS T + G+ L+ D V A GR P ++L L NV
Sbjct: 216 ELSKKGLDLQFNADIARIEKRADGSLAATLKDGRVLEADCVFYATGRRPMLDNLGLENVQ 275
Query: 301 VKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKP---RKT 357
VKL +G ++VDE +T+ P+I A+GD+ R+ LTPVA+ EG A+ +F KP R
Sbjct: 276 VKLDKRGYIEVDELFQTSTPSILALGDVIGRVQLTPVALAEGMAVARRLF--KPEEYRPL 333
Query: 358 DHTRVASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVT 417
D+ + +AVFS+P IGT GL EE A ++ KV ++ S F P+ ++ + + + +V
Sbjct: 334 DYRMIPTAVFSLPNIGTVGLSEEQAIEDGHKVKIFESRFRPMKQTLTECQERTLMKLVVD 393
Query: 418 NHSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTP 474
SD VLG H++G A EIIQ + + L+ A F TIGVHP++AEE ++RTP
Sbjct: 394 ADSD-RVLGCHMVGPEAGEIIQGLAIALKAGATKQVFDETIGVHPSAAEEFVTLRTP 449
>ref|ZP_01910047.1| glutathione-disulfide reductase [Plesiocystis pacifica SIR-1]
gb|EDM77018.1| glutathione-disulfide reductase [Plesiocystis pacifica SIR-1]
Length = 452
Score = 361 bits (926), Expect = 1e-97, Method: Composition-based stats.
Identities = 201/470 (42%), Positives = 280/470 (59%), Gaps = 26/470 (5%)
Query: 5 FDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMV 64
FDL IGAGSGG+ + A YG +VA+ + Y+ +GGTCV GCVPKKL+V
Sbjct: 6 FDLFTIGAGSGGVASSRRAGE-YGAKVAICE---------YSRIGGTCVMRGCVPKKLLV 55
Query: 65 TGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFL 124
GA + +H ++AGFGWE + K +W KL AAK + + + Y + D++ ++
Sbjct: 56 YGASFAEHFEDAAGFGWEV--AEAKLDWAKLEAAKANELDRLEQIYRRLLRDSK-VELIE 112
Query: 125 GWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIEHCISSNEAFYL 184
G G + + V V D K R A+HIL+ATG WP +P IPGIEH I+SNEA L
Sbjct: 113 GRGRIVGPHAVEV----DGK-----RYTAEHILIATGGWPSLPEIPGIEHAITSNEALDL 163
Query: 185 PEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTA 244
P RV VGGG+I VEFAGIFNA G V + R + +LRGFD IRE + +++
Sbjct: 164 AALPERVTIVGGGYIGVEFAGIFNA---AGASVRVLLRGDNVLRGFDTEIRERLAQEMEG 220
Query: 245 NGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLT 304
G++I T + DGS + + D DVV+ A GR+P + DL L VGV+
Sbjct: 221 RGVDICTEVQVRSIEKKADGSLSLFLDDDTFHDTDVVLYATGRLPASKDLGLEAVGVETR 280
Query: 305 PKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRVAS 364
+G + VDE +RT+VP+IYA+GD+TDR+ LTP+AI EG AL +T+F + + D V +
Sbjct: 281 ERGAIVVDEANRTSVPSIYAVGDVTDRINLTPIAIAEGRALAETLFNDNAQIVDRDDVPT 340
Query: 365 AVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDGTV 424
AVFS PP+GT GL EE A F V VY + F P+ ISG + ++ K+V + V
Sbjct: 341 AVFSRPPVGTVGLTEEQARARFAAVDVYAARFRPMKATISG-RNERITMKLVVDRDTDVV 399
Query: 425 LGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMRTP 474
+G H++G+ APEIIQ V + L+ A + F T+G+HP++AEE +MR P
Sbjct: 400 VGAHMVGEDAPEIIQGVAIALKCKATKAQFDATVGIHPSAAEEFVTMRFP 449
>ref|ZP_02188264.1| glutathione-disulfide reductase [alpha proteobacterium BAL199]
gb|EDP64981.1| glutathione-disulfide reductase [alpha proteobacterium BAL199]
Length = 459
Score = 358 bits (918), Expect = 8e-97, Method: Composition-based stats.
Identities = 202/470 (42%), Positives = 285/470 (60%), Gaps = 31/470 (6%)
Query: 5 FDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKKLMV 64
+DL+ IGAGSGG+ A A +G RVAVV+ +GGTCV GCVPKKL+V
Sbjct: 6 YDLITIGAGSGGVRAS-RLAGRFGARVAVVE---------ELRVGGTCVLRGCVPKKLLV 55
Query: 65 TGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFFL 124
G+ + + + + AG+GW +G V +W +IAAK++ + ++ Y + N
Sbjct: 56 YGSHFREEVADMAGYGWSVEG--VSHDWGAMIAAKDKELDRLHGIYMNLLNGA------- 106
Query: 125 GWGSLESKNVVVVRETADPKSAVKE--RLQADHILLATGSWPQMPAIPGIEHCISSNEAF 182
G L+ + VVV DP + E R ++ IL+ATG WP +P +PGIEH I+SNEA
Sbjct: 107 GNTVLDGRGVVV-----DPHTVEVEGKRYTSERILIATGGWPSLPDVPGIEHAITSNEAL 161
Query: 183 YLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQL 242
LP+ P RV VG GFI+VEFAGIFN++ G + L YR + +LRGFDE +R +T +L
Sbjct: 162 DLPQRPERVAIVGSGFIAVEFAGIFNSF---GSETHLIYRADKVLRGFDEDMRIALTGEL 218
Query: 243 TANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVK 302
G+ P ++ D V G+ L+VD VM A GR P T + L +VGV+
Sbjct: 219 KKKGLHQHPETLPTRIEKGAD-CYLVHLSDGEVLEVDAVMYATGRSPNTKGIGLESVGVE 277
Query: 303 LTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFGNKPRKTDHTRV 362
L G V+VDE+SR++V +I+AIGD+TDR+ LTPVA+ EG A +T F N P + DH V
Sbjct: 278 LADNGAVKVDEWSRSSVLSIWAIGDVTDRIQLTPVALAEGQAFAETEFNNNPIRPDHDDV 337
Query: 363 ASAVFSIPPIGTCGLIEEVAAKEFEKVAVYMSSFTPLMHNISGSKYKKFVAKIVTNHSDG 422
SAVFS PPIGT GL E AAK++ + +Y+S F P+ + ++ + + + K+V + +
Sbjct: 338 PSAVFSQPPIGTVGLSEAAAAKKYGALDIYVSGFRPMKYTMTENSERGLM-KLVVDRASQ 396
Query: 423 TVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAEELCSMR 472
V+G H+LG APEIIQ V + +R+ A DF TIG+HPT+AEE +MR
Sbjct: 397 RVVGAHMLGVDAPEIIQGVAIAVRMGATKRDFDRTIGIHPTAAEEFVTMR 446
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|XP_823260.1| trypanothione reductase [Trypanosoma bruce... 780 0.0
sp|P39051|TYTR_TRYBB Trypanothione reductase (TR) (N(1),N(8... 770 0.0
emb|CAO22640.1| unnamed protein product [Vitis vinifera] 759 0.0
sp|P80461|GSHRP_TOBAC Glutathione reductase, chloroplast pr... 757 0.0
gb|AAB70837.1| glutathione reductase (NADPH) [Vitis vinifera] 757 0.0
gb|AAK27157.1|AF349449_1 glutathione reductase [Brassica ju... 756 0.0
gb|AAD28177.1|AF109694_1 glutathione reductase [Brassica ju... 755 0.0
gb|ABF29525.1| dual-targeted glutathione reductase [Phaseol... 755 0.0
sp|P27456|GSHRP_PEA Glutathione reductase, chloroplast/mito... 753 0.0
emb|CAA42921.1| glutathione reductase (NADPH) [Pisum sativum] 753 0.0
sp|P28593|TYTR_TRYCR Trypanothione reductase (TR) (N(1),N(8... 753 0.0
pdb|1NDA|A Chain A, The Structure Of Trypanosoma Cruzi Tryp... 752 0.0
emb|CAN66042.1| hypothetical protein [Vitis vinifera] 752 0.0
ref|YP_001187841.1| glutathione reductase [Pseudomonas mend... 752 0.0
gb|AAK96868.1| Gluthatione reductase, chloroplast precursor... 751 0.0
pdb|1GXF|A Chain A, Crystal Structure Of Trypanosoma Cruzi ... 750 0.0
dbj|BAD27394.1| glutathione reductase [Zinnia elegans] 750 0.0
ref|NP_191026.1| GR (GLUTATHIONE REDUCTASE); glutathione-di... 750 0.0
dbj|BAF80308.1| chloroplastic glutathione reductase [Hordeu... 750 0.0
ref|NP_001049057.1| Os03g0163300 [Oryza sativa (japonica cu... 750 0.0
ref|XP_805296.1| trypanothione reductase [Trypanosoma cruzi... 749 0.0
sp|P13110|TYTR_TRYCO Trypanothione reductase (TR) (N(1),N(8... 749 0.0
ref|YP_260503.1| glutathione reductase [Pseudomonas fluores... 748 0.0
pdb|1BZL|A Chain A, Crystal Structure Of Trypanosoma Cruzi ... 744 0.0
ref|XP_001561849.1| trypanothione reductase [Leishmania bra... 741 0.0
pdb|1AOG|A Chain A, Trypanosoma Cruzi Trypanothione Reducta... 740 0.0
sp|P48640|GSHRP_SOYBN Glutathione reductase, chloroplast pr... 739 0.0
ref|XP_001462998.1| trypanothione reductase [Leishmania inf... 738 0.0
ref|XP_001687512.1| trypanothione reductase [Leishmania maj... 738 0.0
gb|AAF26175.1|AF105199_1 glutathione reductase [Glycine max] 734 0.0
ref|NP_794013.1| glutathione reductase [Pseudomonas syringa... 731 0.0
sp|P39040|TYTR_CRIFA Trypanothione reductase (TR) (N(1),N(8... 731 0.0
ref|YP_405027.1| glutathione reductase [Shigella dysenteria... 731 0.0
ref|ZP_01166092.1| glutathione reductase [Oceanospirillum s... 730 0.0
pdb|1TYP|A Chain A, Substrate Interactions Between Trypanot... 730 0.0
pdb|1FEA|A Chain A, Unliganded Crithidia Fasciculata Trypan... 729 0.0
pdb|1TYT|A Chain A, Crystal And Molecular Structure Of Crit... 728 0.0
ref|NP_888964.1| glutathione reductase [Bordetella bronchis... 725 0.0
ref|XP_001754283.1| predicted protein [Physcomitrella paten... 725 0.0
ref|NP_883660.1| glutathione reductase [Bordetella parapert... 724 0.0
pdb|2TPR|A Chain A, X-Ray Structure Of Trypanothione Reduct... 724 0.0
gb|AAA30323.1| trypanothione reductase 724 0.0
gb|AAA30322.1| trypanothione reductase 723 0.0
sp|P39050|TYTR_LEIDO Trypanothione reductase (TR) (N(1),N(8... 723 0.0
ref|NP_880776.1| glutathione reductase [Bordetella pertussi... 722 0.0
gb|ABQ57410.1| trypanothione reductase [Leishmania amazonen... 722 0.0
ref|YP_001631533.1| probable glutathione reductase [Bordete... 721 0.0
gb|ABB89041.1| glutathione reductase [Vigna unguiculata] 720 0.0
ref|NP_745949.1| glutathione reductase [Pseudomonas putida ... 718 0.0
ref|YP_348659.1| glutathione reductase [Pseudomonas fluores... 718 0.0
gb|ABB89042.1| glutathione reductase [Vigna unguiculata] 718 0.0
gb|ABQ53155.1| chloroplast glutathione reductase [Dasypyrum... 717 0.0
ref|YP_001370639.1| glutathione-disulfide reductase [Ochrob... 717 0.0
ref|NP_001048485.1| Os02g0813500 [Oryza sativa (japonica cu... 716 0.0
ref|YP_001669762.1| glutathione-disulfide reductase [Pseudo... 716 0.0
sp|Q43154|GSHRP_SPIOL Glutathione reductase, chloroplast pr... 714 0.0
ref|YP_001412373.1| glutathione-disulfide reductase [Parvib... 714 0.0
ref|YP_001267277.1| glutathione reductase [Pseudomonas puti... 714 0.0
ref|YP_001750047.1| glutathione-disulfide reductase [Pseudo... 713 0.0
ref|ZP_00830654.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 713 0.0
ref|ZP_03830608.1| glutathione reductase [Pectobacterium ca... 712 0.0
ref|YP_929415.1| glutathione reductase [Shewanella amazonen... 712 0.0
dbj|BAD27393.1| glutathione reductase [Zinnia elegans] 712 0.0
emb|CAO71585.1| unnamed protein product [Vitis vinifera] 712 0.0
ref|YP_001440238.1| hypothetical protein ESA_04222 [Enterob... 711 0.0
ref|NP_671146.1| glutathione reductase [Yersinia pestis KIM... 711 0.0
ref|ZP_03826978.1| glutathione reductase [Pectobacterium ca... 711 0.0
ref|YP_001718880.1| glutathione-disulfide reductase [Yersin... 711 0.0
ref|YP_653712.1| glutathione reductase [Yersinia pestis Ant... 711 0.0
ref|YP_486991.1| Glutathione reductase [Rhodopseudomonas pa... 710 0.0
ref|YP_001008198.1| glutathione reductase [Yersinia enteroc... 710 0.0
ref|NP_407417.1| glutathione reductase [Yersinia pestis CO9... 710 0.0
ref|YP_072299.1| glutathione reductase [Yersinia pseudotube... 710 0.0
ref|YP_791214.1| glutathione reductase [Pseudomonas aerugin... 710 0.0
ref|ZP_00823608.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 710 0.0
ref|ZP_00826822.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 708 0.0
ref|YP_001402993.1| glutathione-disulfide reductase [Yersin... 708 0.0
gb|AAL52153.1| GLUTATHIONE REDUCTASE [Brucella melitensis 16M] 708 0.0
ref|ZP_00834070.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 708 0.0
ref|YP_001348623.1| glutathione reductase [Pseudomonas aeru... 708 0.0
sp|Q43621|GSHRC_PEA Glutathione reductase, cytosolic (GR) (... 707 0.0
ref|YP_001471883.1| glutathione-disulfide reductase [Shewan... 707 0.0
ref|ZP_02958557.1| hypothetical protein PROSTU_00303 [Provi... 707 0.0
ref|YP_048191.1| glutathione reductase [Erwinia carotovora ... 707 0.0
ref|YP_607911.1| glutathione reductase [Pseudomonas entomop... 707 0.0
ref|YP_343613.1| glutathione reductase [Nitrosococcus ocean... 707 0.0
ref|NP_756161.1| glutathione reductase [Escherichia coli CF... 707 0.0
ref|ZP_00726453.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 707 0.0
ref|NP_312399.1| glutathione reductase [Escherichia coli O1... 706 0.0
ref|YP_001460294.1| glutathione-disulfide reductase [Escher... 706 0.0
gb|ABK95991.1| unknown [Populus trichocarpa] 706 0.0
ref|NP_539889.2| glutathione reductase [Brucella melitensis... 706 0.0
gb|ACO66041.1| predicted protein [Micromonas sp. RCC299] 705 0.0
ref|NP_250715.1| glutathione reductase [Pseudomonas aerugin... 705 0.0
ref|ZP_03834627.1| glutathione reductase [Citrobacter young... 705 0.0
ref|NP_709280.1| glutathione reductase [Shigella flexneri 2... 705 0.0
ref|NP_927730.1| glutathione reductase [Photorhabdus lumine... 705 0.0
ref|ZP_00711931.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 705 0.0
dbj|BAA11214.1| Glutathione Reductase [Oryza sativa Japonic... 705 0.0
ref|NP_417957.1| glutathione oxidoreductase [Escherichia co... 705 0.0
ref|YP_001095785.1| glutathione reductase [Shewanella loihi... 705 0.0
ref|ZP_01877738.1| glutathione-disulfide reductase [Roseova... 705 0.0
ref|YP_001337520.1| glutathione reductase [Klebsiella pneum... 704 0.0
ref|NP_698019.1| glutathione reductase [Brucella suis 1330]... 704 0.0
ref|YP_221728.1| glutathione reductase [Brucella abortus bi... 704 0.0
ref|YP_859101.1| glutathione reductase [Escherichia coli AP... 704 0.0
ref|YP_001627684.1| glutathione-disulfide reductase [Brucel... 703 0.0
ref|ZP_01629769.1| glutathione reductase [Nodularia spumige... 703 0.0
gb|ABI35910.1| glutathione reductase [Rheum australe] 703 0.0
ref|NP_290071.1| glutathione reductase [Escherichia coli O1... 703 0.0
ref|ZP_02342939.1| glutathione reductase [Salmonella enteri... 703 0.0
ref|YP_001258952.1| glutathione reductase [Brucella ovis AT... 703 0.0
ref|ZP_00415841.1| FAD-dependent pyridine nucleotide-disulp... 702 0.0
ref|YP_001882115.1| glutathione-disulfide reductase [Shigel... 702 0.0
ref|ZP_01114352.1| glutathione reductase [Reinekea sp. MED2... 702 0.0
ref|YP_001592851.1| glutathione-disulfide reductase [Brucel... 702 0.0
ref|NP_458319.1| glutathione reductase [Salmonella enterica... 702 0.0
ref|ZP_02559524.1| glutathione reductase [Salmonella enteri... 702 0.0
ref|ZP_02649953.1| glutathione reductase [Salmonella enteri... 702 0.0
ref|YP_001590614.1| hypothetical protein SPAB_04466 [Salmon... 702 0.0
ref|ZP_02680248.1| glutathione reductase [Salmonella enteri... 702 0.0
ref|NP_462498.1| glutathione reductase [Salmonella typhimur... 701 0.0
ref|ZP_02901373.1| glutathione-disulfide reductase [Escheri... 701 0.0
ref|ZP_00922995.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 701 0.0
ref|ZP_02941407.1| glutathione-disulfide reductase [Cyanoth... 701 0.0
ref|ZP_02564298.1| hypothetical protein Senten_00700 [Salmo... 700 0.0
ref|ZP_02645510.1| hypothetical protein Senterenterica_0779... 700 0.0
ref|YP_576764.1| Glutathione reductase [Nitrobacter hamburg... 700 0.0
ref|ZP_02156112.1| glutathione reductase [Shewanella benthi... 700 0.0
ref|YP_409811.1| glutathione reductase [Shigella boydii Sb2... 700 0.0
ref|YP_218513.1| glutathione reductase [Salmonella enterica... 700 0.0
ref|YP_001758517.1| glutathione-disulfide reductase [Shewan... 700 0.0
ref|ZP_01901318.1| glutathione-disulfide reductase [Roseoba... 700 0.0
ref|ZP_00998281.1| glutathione-disulfide reductase [Oceanic... 699 0.0
ref|NP_102306.1| glutathione reductase [Mesorhizobium loti ... 699 0.0
gb|ABF74601.1| trypanothione reductase [Leishmania amazonen... 698 0.0
ref|YP_001352656.1| glutathione reductase (NADPH) [Janthino... 698 0.0
ref|YP_001172620.1| glutathione reductase [Pseudomonas stut... 698 0.0
ref|YP_001909236.1| Putative glutathione reductase [Erwinia... 698 0.0
ref|ZP_02188264.1| glutathione-disulfide reductase [alpha p... 698 0.0
ref|XP_001769571.1| predicted protein [Physcomitrella paten... 698 0.0
ref|YP_001480935.1| glutathione-disulfide reductase [Serrat... 698 0.0
sp|O04955|GSHRC_BRARP Glutathione reductase, cytosolic (GR)... 698 0.0
ref|YP_274470.1| glutathione reductase [Pseudomonas syringa... 697 0.0
ref|YP_001456436.1| hypothetical protein CKO_04956 [Citroba... 697 0.0
gb|EEH95367.1| glutathione reductase [Citrobacter sp. 30_2] 697 0.0
ref|YP_735965.1| glutathione reductase [Shewanella sp. MR-4... 697 0.0
ref|YP_001178619.1| glutathione reductase [Enterobacter sp.... 697 0.0
ref|YP_001572974.1| hypothetical protein SARI_04039 [Salmon... 697 0.0
ref|YP_317837.1| glutathione reductase [Nitrobacter winogra... 696 0.0
ref|YP_166571.1| glutathione-disulfide reductase [Silicibac... 696 0.0
ref|YP_527323.1| glutathione reductase [Saccharophagus degr... 696 0.0
ref|ZP_01225841.1| putative glutathione reductase [Aurantim... 695 0.0
ref|ZP_01445717.1| glutathione-disulfide reductase [Roseova... 695 0.0
ref|YP_001617210.1| Glutathione-disulfide reductase [Sorang... 694 0.0
ref|ZP_01545488.1| glutathione reductase [Stappia aggregata... 694 0.0
ref|YP_739972.1| glutathione reductase [Shewanella sp. MR-7... 693 0.0
ref|ZP_02166732.1| glutathione reductase [Hoeflea phototrop... 693 0.0
ref|NP_246172.1| glutathione reductase [Pasteurella multoci... 693 0.0
ref|YP_001503913.1| glutathione-disulfide reductase [Shewan... 693 0.0
ref|ZP_01731018.1| glutathione reductase [Cyanothece sp. CC... 693 0.0
ref|ZP_02976230.1| glutathione-disulfide reductase [Cyanoth... 692 0.0
ref|YP_001120918.1| glutathione-disulfide reductase [Burkho... 692 0.0
ref|YP_569193.1| Glutathione reductase [Rhodopseudomonas pa... 692 0.0
ref|YP_469884.1| glutathione reductase [Rhizobium etli CFN ... 692 0.0
ref|NP_189059.1| ATGR1 (GLUTATHIONE-DISULFIDE REDUCTASE); g... 692 0.0
dbj|BAF80309.1| cytosolic glutathione reductase [Hordeum vu... 692 0.0
ref|YP_370590.1| Glutathione reductase [Burkholderia sp. 38... 692 0.0
gb|AAQ64632.1| cytosolic glutathione reductase [Triticum mo... 691 0.0
gb|AAK25938.1|AF360228_1 putative glutathione reductase [Ar... 691 0.0
ref|YP_001581181.1| glutathione-disulfide reductase [Burkho... 691 0.0
ref|YP_854548.1| glutathione-disulfide reductase [Aeromonas... 691 0.0
gb|EDT30877.1| glutathione-disulfide reductase [Oligotropha... 691 0.0
ref|NP_792904.1| glutathione reductase [Pseudomonas syringa... 690 0.0
ref|YP_871677.1| glutathione reductase [Shewanella sp. ANA-... 690 0.0
ref|ZP_02841341.1| glutathione-disulfide reductase [Thauera... 690 0.0
ref|YP_965339.1| glutathione reductase [Shewanella sp. W3-1... 690 0.0
ref|YP_236051.1| glutathione reductase [Pseudomonas syringa... 690 0.0
gb|EAZ16075.1| hypothetical protein OsJ_030284 [Oryza sativ... 690 0.0
ref|YP_001685169.1| glutathione-disulfide reductase [Caulob... 690 0.0
ref|YP_780913.1| glutathione-disulfide reductase [Rhodopseu... 689 0.0
ref|YP_001672425.1| glutathione-disulfide reductase [Shewan... 689 0.0
ref|YP_958634.1| pyridine nucleotide-disulphide oxidoreduct... 689 0.0
ref|ZP_02300325.1| glutathione-disulfide reductase [Rhodops... 689 0.0
pdb|1GES|A Chain A, Anatomy Of An Engineered Nad-Binding Si... 688 0.0
ref|YP_001139983.1| glutathione oxidoreductase [Aeromonas s... 688 0.0
ref|YP_001556813.1| glutathione-disulfide reductase [Shewan... 688 0.0
ref|NP_720218.1| glutathione reductase [Shewanella oneidens... 688 0.0
gb|EEH55587.1| predicted protein [Micromonas pusilla CCMP1545] 688 0.0
ref|ZP_00987704.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 688 0.0
ref|YP_001806040.1| glutathione reductase [Cyanothece sp. A... 688 0.0
ref|YP_106924.1| glutathione reductase [Burkholderia pseudo... 687 0.0
ref|ZP_00514499.1| Glutathione reductase, plant [Crocosphae... 687 0.0
ref|ZP_01737440.1| glutathione reductase [Marinobacter sp. ... 687 0.0
ref|ZP_01755695.1| glutathione-disulfide reductase [Roseoba... 687 0.0
ref|NP_947328.1| putative glutathione reductase [Rhodopseud... 687 0.0
ref|NP_932858.1| glutathione reductase [Vibrio vulnificus Y... 687 0.0
ref|NP_760056.1| glutathione reductase [Vibrio vulnificus C... 687 0.0
ref|ZP_01841851.1| glutathione-disulfide reductase [Shewane... 687 0.0
ref|YP_001048525.1| glutathione reductase [Shewanella balti... 687 0.0
gb|EAY78480.1| hypothetical protein OsI_032439 [Oryza sativ... 687 0.0
ref|YP_001064600.1| glutathione-disulfide reductase [Burkho... 687 0.0
ref|YP_001181619.1| glutathione reductase [Shewanella putre... 686 0.0
ref|ZP_01705219.1| glutathione-disulfide reductase [Shewane... 686 0.0
ref|XP_001416175.1| glutathione reductase [Ostreococcus luc... 686 0.0
ref|YP_622264.1| Glutathione reductase [Burkholderia cenoce... 686 0.0
ref|ZP_01792982.1| glutathione reductase [Haemophilus influ... 685 0.0
ref|ZP_01910047.1| glutathione-disulfide reductase [Plesioc... 685 0.0
ref|YP_786142.1| glutathione reductase [Bordetella avium 19... 685 0.0
ref|ZP_01789317.1| glutathione reductase [Haemophilus influ... 685 0.0
ref|ZP_01983535.1| glutathione-disulfide reductase [Vibrio ... 684 0.0
ref|ZP_00980913.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 684 0.0
ref|YP_440830.1| glutathione-disulfide reductase [Burkholde... 684 0.0
ref|ZP_01892670.1| glutathione reductase [Marinobacter algi... 683 0.0
ref|ZP_01677316.1| glutathione-disulfide reductase [Vibrio ... 683 0.0
ref|ZP_02380988.1| Glutathione reductase [Burkholderia ubon... 683 0.0
ref|ZP_03875623.1| NADPH-glutathione reductase [Haliangium ... 683 0.0
ref|ZP_01449108.1| glutathione-disulfide reductase [alpha p... 683 0.0
ref|YP_002808959.1| glutathione reductase [Vibrio cholerae ... 683 0.0
ref|YP_756204.1| glutathione-disulfide reductase [Maricauli... 683 0.0
ref|ZP_01751062.1| glutathione reductase [Roseobacter sp. C... 683 0.0
ref|ZP_01971219.1| glutathione-disulfide reductase [Vibrio ... 683 0.0
ref|ZP_01483928.1| hypothetical protein VchoR_02000149 [Vib... 683 0.0
ref|ZP_01955396.1| glutathione-disulfide reductase [Vibrio ... 683 0.0
ref|YP_001292054.1| glutathione reductase [Haemophilus infl... 683 0.0
ref|ZP_01681038.1| glutathione-disulfide reductase [Vibrio ... 683 0.0
ref|YP_002818479.1| glutathione reductase [Vibrio cholerae ... 682 0.0
ref|NP_421105.1| glutathione reductase [Caulobacter crescen... 682 0.0
ref|ZP_01978607.1| glutathione-disulfide reductase [Vibrio ... 682 0.0
ref|YP_752541.1| glutathione reductase [Shewanella frigidim... 682 0.0
ref|ZP_00156004.2| COG1249: Pyruvate/2-oxoglutarate dehydro... 681 0.0
ref|NP_438331.1| glutathione reductase [Haemophilus influen... 681 0.0
ref|YP_001368438.1| glutathione-disulfide reductase [Shewan... 681 0.0
ref|YP_001766305.1| glutathione-disulfide reductase [Burkho... 681 0.0
ref|ZP_01475588.1| hypothetical protein VEx2w_02001798 [Vib... 681 0.0
ref|YP_001290323.1| glutathione reductase [Haemophilus infl... 681 0.0
ref|NP_796447.1| glutathione reductase [Vibrio parahaemolyt... 681 0.0
ref|ZP_01787054.1| glutathione reductase [Haemophilus influ... 680 0.0
ref|ZP_01478949.1| hypothetical protein VchoM_02001917 [Vib... 680 0.0
ref|ZP_01046382.1| glutathione reductase [Nitrobacter sp. N... 680 0.0
ref|ZP_01784260.1| glutathione reductase [Haemophilus influ... 680 0.0
emb|CAM76458.1| Glutathione reductase, plant [Magnetospiril... 680 0.0
ref|NP_229843.1| glutathione reductase [Vibrio cholerae O1 ... 680 0.0
ref|ZP_01797072.1| glutathione reductase [Haemophilus influ... 680 0.0
emb|CAO91430.1| gor [Microcystis aeruginosa PCC 7806] 680 0.0
ref|YP_247881.1| glutathione reductase [Haemophilus influen... 680 0.0
ref|ZP_01237274.1| glutathione reductase [Vibrio angustum S... 680 0.0
gb|AAB59211.1| trypanothione reductase [Trypanosoma cruzi] 680 0.0
ref|ZP_01042946.1| glutathione reductase [Idiomarina baltic... 680 0.0
ref|YP_001659640.1| glutathione reductase [Microcystis aeru... 680 0.0
ref|ZP_01260163.1| glutathione reductase [Vibrio alginolyti... 679 0.0
gb|ABB88584.1| glutathione reductase [Ulva fasciata] 679 0.0
gb|ABF29524.1| cytosolic glutathione reductase [Phaseolus v... 679 0.0
ref|YP_425773.1| Glutathione reductase [Rhodospirillum rubr... 679 0.0
ref|ZP_01215489.1| Pyruvate/2-oxoglutarate dehydrogenase co... 679 0.0
ref|ZP_01868092.1| glutathione reductase [Vibrio shilonii A... 678 0.0
ref|YP_156710.1| glutathione reductase [Idiomarina loihiens... 678 0.0
ref|ZP_00154718.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 678 0.0
ref|YP_001809607.1| glutathione-disulfide reductase [Burkho... 678 0.0
ref|YP_001167092.1| glutathione-disulfide reductase [Rhodob... 678 0.0
ref|YP_205872.1| glutathione oxidoreductase [Vibrio fischer... 678 0.0
ref|ZP_02908997.1| glutathione-disulfide reductase [Burkhol... 678 0.0
ref|ZP_01160380.1| glutathione reductase [Photobacterium sp... 678 0.0
ref|YP_564590.1| glutathione reductase [Shewanella denitrif... 677 0.0
ref|YP_001043878.1| glutathione-disulfide reductase [Rhodob... 677 0.0
ref|YP_322757.1| glutathione reductase [Anabaena variabilis... 677 0.0
ref|YP_774940.1| glutathione-disulfide reductase [Burkholde... 677 0.0
ref|ZP_02145082.1| Glutathione reductase [Phaeobacter galla... 677 0.0
ref|YP_353433.1| probable glutathione reductase [Rhodobacte... 676 0.0
ref|ZP_01986467.1| glutathione-disulfide reductase [Vibrio ... 676 0.0
ref|ZP_02148155.1| glutathione-disulfide reductase [Phaeoba... 676 0.0
ref|ZP_02892722.1| glutathione-disulfide reductase [Burkhol... 675 0.0
dbj|BAB33285.1| glutathione reductase [Acinetobacter sp. M-1] 675 0.0
ref|ZP_02196067.1| glutathione reductase [Vibrio campbellii... 675 0.0
ref|ZP_02153429.1| glutathione reductase [Oceanibulbus indo... 675 0.0
ref|YP_674022.1| glutathione reductase [Mesorhizobium sp. B... 675 0.0
ref|YP_421029.1| Glutathione reductase [Magnetospirillum ma... 675 0.0
ref|ZP_01616723.1| glutathione reductase [marine gamma prot... 675 0.0
ref|ZP_01625531.1| glutathione reductase [marine gamma prot... 675 0.0
ref|ZP_01899743.1| glutathione reductase [Moritella sp. PE3... 674 0.0
ref|YP_001239484.1| glutathione reductase [Bradyrhizobium s... 674 0.0
ref|YP_001443753.1| glutathione reductase [Vibrio harveyi A... 674 0.0
ref|ZP_01304178.1| pyridine nucleotide-disulphide oxidoredu... 673 0.0
ref|ZP_02479102.1| aminopeptidase B [Haemophilus parasuis 2... 673 0.0
ref|NP_489008.1| glutathione reductase [Nostoc sp. PCC 7120... 673 0.0
ref|YP_453748.1| glutathione reductase [Sodalis glossinidiu... 673 0.0
ref|ZP_01623681.1| glutathione reductase [Lyngbya sp. PCC 8... 673 0.0
ref|ZP_00960040.1| glutathione-disulfide reductase [Roseova... 673 0.0
ref|YP_616265.1| glutathione reductase [Sphingopyxis alaske... 673 0.0
ref|ZP_00108447.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 673 0.0
ref|ZP_01104150.1| trypanothione reductase [gamma proteobac... 673 0.0
ref|YP_001652255.1| glutathione oxidoreductase [Actinobacil... 673 0.0
ref|NP_770397.1| glutathione reductase [Bradyrhizobium japo... 673 0.0
ref|ZP_02138234.1| glutathione reductase [Vibrio fischeri M... 672 0.0
ref|YP_001280894.1| glutathione reductase [Psychrobacter sp... 672 0.0
ref|ZP_00207996.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 672 0.0
ref|ZP_01813280.1| glutathione reductase [Vibrionales bacte... 672 0.0
ref|ZP_02858777.1| glutathione-disulfide reductase [Rhizobi... 671 0.0
ref|YP_001784403.1| glutathione-disulfide reductase [Haemop... 671 0.0
dbj|BAD14936.1| glutathione reductase [Brassica oleracea] 671 0.0
Sequences not found previously or not previously below threshold:
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
emb|CAO22640.1| unnamed protein product [Vitis vinifera] 784 0.0
gb|AAB70837.1| glutathione reductase (NADPH) [Vitis vinifera] 780 0.0
gb|ABF29525.1| dual-targeted glutathione reductase [Phaseol... 779 0.0
sp|P80461|GSHRP_TOBAC Glutathione reductase, chloroplast pr... 778 0.0
gb|AAK27157.1|AF349449_1 glutathione reductase [Brassica ju... 777 0.0
gb|AAD28177.1|AF109694_1 glutathione reductase [Brassica ju... 776 0.0
emb|CAN66042.1| hypothetical protein [Vitis vinifera] 775 0.0
dbj|BAD27394.1| glutathione reductase [Zinnia elegans] 775 0.0
sp|P27456|GSHRP_PEA Glutathione reductase, chloroplast/mito... 774 0.0
ref|NP_001049057.1| Os03g0163300 [Oryza sativa (japonica cu... 774 0.0
emb|CAA42921.1| glutathione reductase (NADPH) [Pisum sativum] 774 0.0
dbj|BAF80308.1| chloroplastic glutathione reductase [Hordeu... 774 0.0
gb|AAK96868.1| Gluthatione reductase, chloroplast precursor... 772 0.0
ref|NP_191026.1| GR (GLUTATHIONE REDUCTASE); glutathione-di... 770 0.0
ref|YP_001187841.1| glutathione reductase [Pseudomonas mend... 764 0.0
ref|YP_260503.1| glutathione reductase [Pseudomonas fluores... 760 0.0
sp|P48640|GSHRP_SOYBN Glutathione reductase, chloroplast pr... 759 0.0
gb|AAF26175.1|AF105199_1 glutathione reductase [Glycine max] 755 0.0
ref|YP_405027.1| glutathione reductase [Shigella dysenteria... 755 0.0
ref|XP_001754283.1| predicted protein [Physcomitrella paten... 745 0.0
ref|NP_794013.1| glutathione reductase [Pseudomonas syringa... 745 0.0
ref|ZP_01166092.1| glutathione reductase [Oceanospirillum s... 745 0.0
ref|XP_823260.1| trypanothione reductase [Trypanosoma bruce... 743 0.0
ref|XP_001687512.1| trypanothione reductase [Leishmania maj... 742 0.0
gb|ABQ53155.1| chloroplast glutathione reductase [Dasypyrum... 741 0.0
gb|ABB89041.1| glutathione reductase [Vigna unguiculata] 741 0.0
gb|ABB89042.1| glutathione reductase [Vigna unguiculata] 740 0.0
ref|XP_001462998.1| trypanothione reductase [Leishmania inf... 740 0.0
ref|NP_001048485.1| Os02g0813500 [Oryza sativa (japonica cu... 740 0.0
ref|ZP_00830654.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 737 0.0
ref|NP_888964.1| glutathione reductase [Bordetella bronchis... 737 0.0
sp|Q43154|GSHRP_SPIOL Glutathione reductase, chloroplast pr... 737 0.0
sp|P39051|TYTR_TRYBB Trypanothione reductase (TR) (N(1),N(8... 735 0.0
ref|YP_001370639.1| glutathione-disulfide reductase [Ochrob... 735 0.0
ref|NP_883660.1| glutathione reductase [Bordetella parapert... 735 0.0
ref|YP_001718880.1| glutathione-disulfide reductase [Yersin... 735 0.0
ref|YP_001440238.1| hypothetical protein ESA_04222 [Enterob... 735 0.0
ref|NP_671146.1| glutathione reductase [Yersinia pestis KIM... 735 0.0
ref|YP_001008198.1| glutathione reductase [Yersinia enteroc... 735 0.0
dbj|BAD27393.1| glutathione reductase [Zinnia elegans] 734 0.0
ref|YP_653712.1| glutathione reductase [Yersinia pestis Ant... 734 0.0
ref|YP_072299.1| glutathione reductase [Yersinia pseudotube... 734 0.0
ref|NP_407417.1| glutathione reductase [Yersinia pestis CO9... 734 0.0
ref|ZP_03830608.1| glutathione reductase [Pectobacterium ca... 734 0.0
ref|YP_929415.1| glutathione reductase [Shewanella amazonen... 733 0.0
ref|NP_880776.1| glutathione reductase [Bordetella pertussi... 733 0.0
ref|ZP_00823608.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 733 0.0
ref|YP_348659.1| glutathione reductase [Pseudomonas fluores... 733 0.0
ref|YP_001631533.1| probable glutathione reductase [Bordete... 733 0.0
ref|YP_001402993.1| glutathione-disulfide reductase [Yersin... 732 0.0
ref|ZP_03826978.1| glutathione reductase [Pectobacterium ca... 732 0.0
ref|ZP_00826822.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 732 0.0
ref|NP_745949.1| glutathione reductase [Pseudomonas putida ... 732 0.0
ref|XP_001561849.1| trypanothione reductase [Leishmania bra... 732 0.0
ref|ZP_00834070.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 732 0.0
emb|CAO71585.1| unnamed protein product [Vitis vinifera] 731 0.0
ref|NP_756161.1| glutathione reductase [Escherichia coli CF... 730 0.0
ref|ZP_00726453.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 730 0.0
ref|NP_312399.1| glutathione reductase [Escherichia coli O1... 730 0.0
ref|YP_001412373.1| glutathione-disulfide reductase [Parvib... 729 0.0
ref|YP_001460294.1| glutathione-disulfide reductase [Escher... 729 0.0
ref|YP_001669762.1| glutathione-disulfide reductase [Pseudo... 729 0.0
ref|ZP_03834627.1| glutathione reductase [Citrobacter young... 729 0.0
ref|YP_001337520.1| glutathione reductase [Klebsiella pneum... 729 0.0
dbj|BAA11214.1| Glutathione Reductase [Oryza sativa Japonic... 729 0.0
ref|NP_709280.1| glutathione reductase [Shigella flexneri 2... 728 0.0
ref|YP_048191.1| glutathione reductase [Erwinia carotovora ... 728 0.0
gb|ABK95991.1| unknown [Populus trichocarpa] 728 0.0
ref|ZP_00711931.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 728 0.0
gb|AAL52153.1| GLUTATHIONE REDUCTASE [Brucella melitensis 16M] 728 0.0
sp|Q43621|GSHRC_PEA Glutathione reductase, cytosolic (GR) (... 727 0.0
ref|YP_859101.1| glutathione reductase [Escherichia coli AP... 727 0.0
ref|YP_001267277.1| glutathione reductase [Pseudomonas puti... 727 0.0
ref|NP_417957.1| glutathione oxidoreductase [Escherichia co... 727 0.0
ref|NP_927730.1| glutathione reductase [Photorhabdus lumine... 727 0.0
ref|YP_001750047.1| glutathione-disulfide reductase [Pseudo... 727 0.0
ref|YP_486991.1| Glutathione reductase [Rhodopseudomonas pa... 727 0.0
ref|ZP_02342939.1| glutathione reductase [Salmonella enteri... 727 0.0
ref|ZP_02958557.1| hypothetical protein PROSTU_00303 [Provi... 727 0.0
ref|NP_290071.1| glutathione reductase [Escherichia coli O1... 726 0.0
gb|ACO66041.1| predicted protein [Micromonas sp. RCC299] 726 0.0
ref|ZP_02559524.1| glutathione reductase [Salmonella enteri... 726 0.0
ref|NP_458319.1| glutathione reductase [Salmonella enterica... 726 0.0
ref|ZP_02649953.1| glutathione reductase [Salmonella enteri... 725 0.0
ref|ZP_02680248.1| glutathione reductase [Salmonella enteri... 725 0.0
ref|NP_539889.2| glutathione reductase [Brucella melitensis... 725 0.0
ref|NP_462498.1| glutathione reductase [Salmonella typhimur... 725 0.0
ref|ZP_02901373.1| glutathione-disulfide reductase [Escheri... 725 0.0
ref|YP_001590614.1| hypothetical protein SPAB_04466 [Salmon... 725 0.0
sp|P28593|TYTR_TRYCR Trypanothione reductase (TR) (N(1),N(8... 725 0.0
sp|P39050|TYTR_LEIDO Trypanothione reductase (TR) (N(1),N(8... 725 0.0
pdb|1NDA|A Chain A, The Structure Of Trypanosoma Cruzi Tryp... 725 0.0
gb|ABQ57410.1| trypanothione reductase [Leishmania amazonen... 725 0.0
ref|YP_001882115.1| glutathione-disulfide reductase [Shigel... 724 0.0
ref|YP_791214.1| glutathione reductase [Pseudomonas aerugin... 724 0.0
ref|YP_218513.1| glutathione reductase [Salmonella enterica... 724 0.0
ref|ZP_01877738.1| glutathione-disulfide reductase [Roseova... 724 0.0
ref|YP_001471883.1| glutathione-disulfide reductase [Shewan... 724 0.0
ref|ZP_02564298.1| hypothetical protein Senten_00700 [Salmo... 724 0.0
ref|ZP_02645510.1| hypothetical protein Senterenterica_0779... 724 0.0
ref|ZP_00922995.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 724 0.0
ref|NP_698019.1| glutathione reductase [Brucella suis 1330]... 723 0.0
ref|YP_221728.1| glutathione reductase [Brucella abortus bi... 723 0.0
ref|YP_001627684.1| glutathione-disulfide reductase [Brucel... 723 0.0
sp|P13110|TYTR_TRYCO Trypanothione reductase (TR) (N(1),N(8... 723 0.0
pdb|1GXF|A Chain A, Crystal Structure Of Trypanosoma Cruzi ... 723 0.0
gb|ABI35910.1| glutathione reductase [Rheum australe] 723 0.0
ref|YP_001095785.1| glutathione reductase [Shewanella loihi... 723 0.0
ref|YP_001258952.1| glutathione reductase [Brucella ovis AT... 722 0.0
ref|YP_409811.1| glutathione reductase [Shigella boydii Sb2... 722 0.0
ref|YP_001348623.1| glutathione reductase [Pseudomonas aeru... 722 0.0
ref|YP_001592851.1| glutathione-disulfide reductase [Brucel... 721 0.0
ref|XP_805296.1| trypanothione reductase [Trypanosoma cruzi... 721 0.0
ref|YP_607911.1| glutathione reductase [Pseudomonas entomop... 721 0.0
ref|YP_001178619.1| glutathione reductase [Enterobacter sp.... 721 0.0
gb|EEH95367.1| glutathione reductase [Citrobacter sp. 30_2] 720 0.0
ref|YP_001480935.1| glutathione-disulfide reductase [Serrat... 720 0.0
ref|ZP_01114352.1| glutathione reductase [Reinekea sp. MED2... 720 0.0
ref|YP_001456436.1| hypothetical protein CKO_04956 [Citroba... 720 0.0
ref|NP_250715.1| glutathione reductase [Pseudomonas aerugin... 720 0.0
ref|ZP_01901318.1| glutathione-disulfide reductase [Roseoba... 720 0.0
sp|O04955|GSHRC_BRARP Glutathione reductase, cytosolic (GR)... 720 0.0
ref|YP_001572974.1| hypothetical protein SARI_04039 [Salmon... 719 0.0
ref|YP_001758517.1| glutathione-disulfide reductase [Shewan... 718 0.0
ref|YP_001909236.1| Putative glutathione reductase [Erwinia... 718 0.0
ref|NP_246172.1| glutathione reductase [Pasteurella multoci... 718 0.0
ref|YP_343613.1| glutathione reductase [Nitrosococcus ocean... 718 0.0
ref|ZP_02156112.1| glutathione reductase [Shewanella benthi... 717 0.0
pdb|1BZL|A Chain A, Crystal Structure Of Trypanosoma Cruzi ... 717 0.0
sp|P39040|TYTR_CRIFA Trypanothione reductase (TR) (N(1),N(8... 717 0.0
ref|ZP_00415841.1| FAD-dependent pyridine nucleotide-disulp... 717 0.0
ref|YP_576764.1| Glutathione reductase [Nitrobacter hamburg... 716 0.0
ref|YP_166571.1| glutathione-disulfide reductase [Silicibac... 716 0.0
ref|YP_001352656.1| glutathione reductase (NADPH) [Janthino... 716 0.0
ref|XP_001769571.1| predicted protein [Physcomitrella paten... 716 0.0
ref|YP_735965.1| glutathione reductase [Shewanella sp. MR-4... 716 0.0
ref|NP_189059.1| ATGR1 (GLUTATHIONE-DISULFIDE REDUCTASE); g... 716 0.0
pdb|1TYP|A Chain A, Substrate Interactions Between Trypanot... 716 0.0
ref|ZP_00998281.1| glutathione-disulfide reductase [Oceanic... 715 0.0
dbj|BAF80309.1| cytosolic glutathione reductase [Hordeum vu... 715 0.0
gb|AAK25938.1|AF360228_1 putative glutathione reductase [Ar... 715 0.0
pdb|1FEA|A Chain A, Unliganded Crithidia Fasciculata Trypan... 714 0.0
ref|ZP_01629769.1| glutathione reductase [Nodularia spumige... 714 0.0
pdb|1TYT|A Chain A, Crystal And Molecular Structure Of Crit... 714 0.0
ref|NP_102306.1| glutathione reductase [Mesorhizobium loti ... 713 0.0
ref|ZP_02188264.1| glutathione-disulfide reductase [alpha p... 713 0.0
pdb|1AOG|A Chain A, Trypanosoma Cruzi Trypanothione Reducta... 713 0.0
gb|AAQ64632.1| cytosolic glutathione reductase [Triticum mo... 713 0.0
ref|YP_317837.1| glutathione reductase [Nitrobacter winogra... 713 0.0
ref|YP_854548.1| glutathione-disulfide reductase [Aeromonas... 712 0.0
ref|YP_739972.1| glutathione reductase [Shewanella sp. MR-7... 712 0.0
ref|ZP_02941407.1| glutathione-disulfide reductase [Cyanoth... 711 0.0
pdb|1GES|A Chain A, Anatomy Of An Engineered Nad-Binding Si... 711 0.0
ref|YP_001503913.1| glutathione-disulfide reductase [Shewan... 711 0.0
ref|ZP_01545488.1| glutathione reductase [Stappia aggregata... 711 0.0
ref|YP_001139983.1| glutathione oxidoreductase [Aeromonas s... 710 0.0
ref|YP_274470.1| glutathione reductase [Pseudomonas syringa... 710 0.0
ref|YP_001172620.1| glutathione reductase [Pseudomonas stut... 710 0.0
gb|EAZ16075.1| hypothetical protein OsJ_030284 [Oryza sativ... 710 0.0
pdb|2TPR|A Chain A, X-Ray Structure Of Trypanothione Reduct... 709 0.0
gb|AAA30323.1| trypanothione reductase 709 0.0
gb|AAA30322.1| trypanothione reductase 709 0.0
ref|YP_001617210.1| Glutathione-disulfide reductase [Sorang... 709 0.0
ref|YP_871677.1| glutathione reductase [Shewanella sp. ANA-... 708 0.0
ref|ZP_01225841.1| putative glutathione reductase [Aurantim... 708 0.0
ref|ZP_01983535.1| glutathione-disulfide reductase [Vibrio ... 708 0.0
ref|YP_527323.1| glutathione reductase [Saccharophagus degr... 708 0.0
ref|ZP_01789317.1| glutathione reductase [Haemophilus influ... 708 0.0
ref|ZP_01445717.1| glutathione-disulfide reductase [Roseova... 708 0.0
ref|ZP_01792982.1| glutathione reductase [Haemophilus influ... 708 0.0
ref|NP_932858.1| glutathione reductase [Vibrio vulnificus Y... 708 0.0
ref|NP_760056.1| glutathione reductase [Vibrio vulnificus C... 708 0.0
ref|YP_965339.1| glutathione reductase [Shewanella sp. W3-1... 708 0.0
ref|YP_569193.1| Glutathione reductase [Rhodopseudomonas pa... 707 0.0
ref|ZP_01677316.1| glutathione-disulfide reductase [Vibrio ... 707 0.0
ref|YP_002808959.1| glutathione reductase [Vibrio cholerae ... 707 0.0
ref|NP_720218.1| glutathione reductase [Shewanella oneidens... 707 0.0
ref|ZP_01483928.1| hypothetical protein VchoR_02000149 [Vib... 707 0.0
ref|ZP_01971219.1| glutathione-disulfide reductase [Vibrio ... 707 0.0
ref|ZP_01955396.1| glutathione-disulfide reductase [Vibrio ... 707 0.0
ref|YP_001672425.1| glutathione-disulfide reductase [Shewan... 707 0.0
ref|YP_469884.1| glutathione reductase [Rhizobium etli CFN ... 706 0.0
ref|YP_001556813.1| glutathione-disulfide reductase [Shewan... 706 0.0
gb|EAY78480.1| hypothetical protein OsI_032439 [Oryza sativ... 706 0.0
ref|ZP_01681038.1| glutathione-disulfide reductase [Vibrio ... 706 0.0
ref|ZP_01978607.1| glutathione-disulfide reductase [Vibrio ... 706 0.0
ref|ZP_02166732.1| glutathione reductase [Hoeflea phototrop... 706 0.0
ref|YP_002818479.1| glutathione reductase [Vibrio cholerae ... 706 0.0
gb|EEH55587.1| predicted protein [Micromonas pusilla CCMP1545] 705 0.0
ref|YP_001292054.1| glutathione reductase [Haemophilus infl... 705 0.0
ref|YP_236051.1| glutathione reductase [Pseudomonas syringa... 705 0.0
ref|NP_792904.1| glutathione reductase [Pseudomonas syringa... 705 0.0
ref|YP_780913.1| glutathione-disulfide reductase [Rhodopseu... 704 0.0
ref|ZP_01841851.1| glutathione-disulfide reductase [Shewane... 704 0.0
gb|EDT30877.1| glutathione-disulfide reductase [Oligotropha... 704 0.0
ref|ZP_00156004.2| COG1249: Pyruvate/2-oxoglutarate dehydro... 704 0.0
ref|ZP_01478949.1| hypothetical protein VchoM_02001917 [Vib... 704 0.0
ref|NP_229843.1| glutathione reductase [Vibrio cholerae O1 ... 704 0.0
ref|YP_001685169.1| glutathione-disulfide reductase [Caulob... 704 0.0
ref|NP_438331.1| glutathione reductase [Haemophilus influen... 704 0.0
ref|ZP_01755695.1| glutathione-disulfide reductase [Roseoba... 704 0.0
ref|YP_001048525.1| glutathione reductase [Shewanella balti... 703 0.0
ref|YP_001290323.1| glutathione reductase [Haemophilus infl... 703 0.0
ref|ZP_01784260.1| glutathione reductase [Haemophilus influ... 703 0.0
ref|YP_001181619.1| glutathione reductase [Shewanella putre... 703 0.0
ref|ZP_01787054.1| glutathione reductase [Haemophilus influ... 703 0.0
ref|ZP_01705219.1| glutathione-disulfide reductase [Shewane... 703 0.0
ref|ZP_01731018.1| glutathione reductase [Cyanothece sp. CC... 703 0.0
ref|ZP_01475588.1| hypothetical protein VEx2w_02001798 [Vib... 703 0.0
ref|ZP_02841341.1| glutathione-disulfide reductase [Thauera... 703 0.0
ref|NP_796447.1| glutathione reductase [Vibrio parahaemolyt... 703 0.0
ref|ZP_01797072.1| glutathione reductase [Haemophilus influ... 702 0.0
ref|YP_247881.1| glutathione reductase [Haemophilus influen... 702 0.0
ref|ZP_02300325.1| glutathione-disulfide reductase [Rhodops... 702 0.0
ref|ZP_02976230.1| glutathione-disulfide reductase [Cyanoth... 702 0.0
ref|ZP_01237274.1| glutathione reductase [Vibrio angustum S... 702 0.0
ref|ZP_01215489.1| Pyruvate/2-oxoglutarate dehydrogenase co... 702 0.0
ref|ZP_01260163.1| glutathione reductase [Vibrio alginolyti... 701 0.0
ref|YP_958634.1| pyridine nucleotide-disulphide oxidoreduct... 701 0.0
ref|ZP_00154718.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 701 0.0
ref|ZP_01751062.1| glutathione reductase [Roseobacter sp. C... 700 0.0
ref|NP_947328.1| putative glutathione reductase [Rhodopseud... 700 0.0
ref|ZP_01449108.1| glutathione-disulfide reductase [alpha p... 700 0.0
ref|YP_752541.1| glutathione reductase [Shewanella frigidim... 699 0.0
ref|XP_001416175.1| glutathione reductase [Ostreococcus luc... 699 0.0
ref|ZP_01868092.1| glutathione reductase [Vibrio shilonii A... 699 0.0
ref|YP_370590.1| Glutathione reductase [Burkholderia sp. 38... 699 0.0
ref|ZP_00514499.1| Glutathione reductase, plant [Crocosphae... 699 0.0
ref|NP_421105.1| glutathione reductase [Caulobacter crescen... 699 0.0
ref|YP_786142.1| glutathione reductase [Bordetella avium 19... 699 0.0
ref|YP_001120918.1| glutathione-disulfide reductase [Burkho... 699 0.0
ref|ZP_01160380.1| glutathione reductase [Photobacterium sp... 698 0.0
ref|YP_756204.1| glutathione-disulfide reductase [Maricauli... 698 0.0
ref|YP_001581181.1| glutathione-disulfide reductase [Burkho... 698 0.0
ref|YP_001368438.1| glutathione-disulfide reductase [Shewan... 698 0.0
ref|YP_001806040.1| glutathione reductase [Cyanothece sp. A... 698 0.0
gb|ABF74601.1| trypanothione reductase [Leishmania amazonen... 698 0.0
ref|YP_001652255.1| glutathione oxidoreductase [Actinobacil... 697 0.0
ref|YP_001167092.1| glutathione-disulfide reductase [Rhodob... 697 0.0
ref|ZP_01042946.1| glutathione reductase [Idiomarina baltic... 697 0.0
ref|ZP_01046382.1| glutathione reductase [Nitrobacter sp. N... 697 0.0
ref|ZP_01986467.1| glutathione-disulfide reductase [Vibrio ... 697 0.0
ref|YP_205872.1| glutathione oxidoreductase [Vibrio fischer... 697 0.0
ref|YP_156710.1| glutathione reductase [Idiomarina loihiens... 696 0.0
ref|YP_106924.1| glutathione reductase [Burkholderia pseudo... 696 0.0
ref|ZP_03875623.1| NADPH-glutathione reductase [Haliangium ... 696 0.0
ref|ZP_01737440.1| glutathione reductase [Marinobacter sp. ... 696 0.0
gb|ABF29524.1| cytosolic glutathione reductase [Phaseolus v... 696 0.0
ref|YP_453748.1| glutathione reductase [Sodalis glossinidiu... 696 0.0
ref|ZP_02196067.1| glutathione reductase [Vibrio campbellii... 696 0.0
ref|YP_001064600.1| glutathione-disulfide reductase [Burkho... 696 0.0
ref|ZP_00987704.1| COG1249: Pyruvate/2-oxoglutarate dehydro... 695 0.0
dbj|BAB33285.1| glutathione reductase [Acinetobacter sp. M-1] 695 0.0
ref|ZP_02479102.1| aminopeptidase B [Haemophilus parasuis 2... 695 0.0
ref|ZP_01899743.1| glutathione reductase [Moritella sp. PE3... 695 0.0
ref|YP_001784403.1| glutathione-disulfide reductase [Haemop... 695 0.0
emb|CAM76458.1| Glutathione reductase, plant [Magnetospiril... 695 0.0
ref|YP_001443753.1| glutathione reductase [Vibrio harveyi A... 695 0.0
gb|ABB88584.1| glutathione reductase [Ulva fasciata] 694 0.0
ref|YP_564590.1| glutathione reductase [Shewanella denitrif... 694 0.0
ref|ZP_01892670.1| glutathione reductase [Marinobacter algi... 694 0.0
ref|YP_353433.1| probable glutathione reductase [Rhodobacte... 693 0.0
ref|ZP_01910047.1| glutathione-disulfide reductase [Plesioc... 693 0.0
dbj|BAD14936.1| glutathione reductase [Brassica oleracea] 693 0.0
ref|ZP_00135555.2| COG1249: Pyruvate/2-oxoglutarate dehydro... 693 0.0
ref|YP_425773.1| Glutathione reductase [Rhodospirillum rubr... 693 0.0
ref|ZP_02145082.1| Glutathione reductase [Phaeobacter galla... 693 0.0
ref|YP_001043878.1| glutathione-disulfide reductase [Rhodob... 693 0.0
ref|ZP_01304178.1| pyridine nucleotide-disulphide oxidoredu... 692 0.0
ref|ZP_02148155.1| glutathione-disulfide reductase [Phaeoba... 692 0.0
ref|YP_001239484.1| glutathione reductase [Bradyrhizobium s... 692 0.0
ref|YP_674022.1| glutathione reductase [Mesorhizobium sp. B... 692 0.0
ref|YP_719318.1| glutathione reductase [Haemophilus somnus ... 692 0.0
ref|YP_663759.1| glutathione-disulfide reductase [Pseudoalt... 692 0.0
ref|ZP_02138234.1| glutathione reductase [Vibrio fischeri M... 692 0.0
ref|YP_622264.1| Glutathione reductase [Burkholderia cenoce... 692 0.0
ref|ZP_01813280.1| glutathione reductase [Vibrionales bacte... 692 0.0
ref|ZP_01133379.1| glutathione reductase [Pseudoalteromonas... 691 0.0
ref|YP_440830.1| glutathione-disulfide reductase [Burkholde... 691 0.0
ref|YP_001280894.1| glutathione reductase [Psychrobacter sp... 691 0.0
ref|YP_001659640.1| glutathione reductase [Microcystis aeru... 691 0.0
ref|YP_089177.1| glutathione reductase [Mannheimia succinic... 691 0.0
ref|ZP_00229909.1| glutathione reductase [Listeria monocyto... 691 0.0
ref|ZP_01616723.1| glutathione reductase [marine gamma prot... 691 0.0
emb|CAO91430.1| gor [Microcystis aeruginosa PCC 7806] 691 0.0
gb|EDN73137.1| glutathione-disulfide reductase [Mannheimia ... 691 0.0
ref|YP_616265.1| glutathione reductase [Sphingopyxis alaske... 690 0.0
ref|ZP_02380988.1| Glutathione reductase [Burkholderia ubon... 690 0.0
ref|ZP_00989309.1| glutathione reductase [Vibrio splendidus... 690 0.0
ref|ZP_00232528.1| glutathione reductase [Listeria monocyto... 690 0.0
ref|ZP_01064942.1| glutathione reductase [Vibrio sp. MED222... 690 0.0
ref|YP_001345305.1| glutathione-disulfide reductase [Actino... 690 0.0
ref|ZP_01929535.1| glutathione reductase [Listeria monocyto... 690 0.0
ref|NP_464432.1| glutathione reductase [Listeria monocytoge... 690 0.0
ref|YP_421029.1| Glutathione reductase [Magnetospirillum ma... 689 0.0
ref|ZP_00960040.1| glutathione-disulfide reductase [Roseova... 689 0.0
ref|YP_013530.1| glutathione reductase [Listeria monocytoge... 689 0.0
ref|ZP_02153429.1| glutathione reductase [Oceanibulbus indo... 689 0.0
ref|ZP_02687442.1| glutathione reductase [Listeria monocyto... 689 0.0
ref|ZP_02276805.1| glutathione reductase [Listeria monocyto... 689 0.0
Sequences not found previously or not previously below threshold:
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.316 0.201 0.719
Lambda K H
0.267 0.0616 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,916,774,664
Number of Sequences: 6899187
Number of extensions: 777536667
Number of successful extensions: 1724780
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 18411
Number of HSP's successfully gapped in prelim test: 21737
Number of HSP's that attempted gapping in prelim test: 1545172
Number of HSP's gapped (non-prelim): 72595
length of query: 492
length of database: 2,350,152,223
effective HSP length: 138
effective length of query: 354
effective length of database: 1,398,064,417
effective search space: 494914803618
effective search space used: 494914803618
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 82 (35.6 bits)