BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= EAN79468.1__[Trypanosoma_brucei]
(555 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_828580.1| fumarate hydratase class I [Trypanosoma br... 1155 0.0
ref|XP_804521.1| fumarate hydratase, putative [Trypanosoma ... 983 0.0
ref|XP_817100.1| fumarate hydratase, putative [Trypanosoma ... 983 0.0
ref|XP_001565298.1| fumarate hydratase, putative [Leishmani... 887 0.0
ref|XP_001683549.1| fumarate hydratase, putative [Leishmani... 887 0.0
gb|EEJ97739.1| fumarase [Thermomonospora curvata DSM 43183] 726 0.0
ref|YP_745628.1| fumarate hydratase [Granulibacter bethesde... 714 0.0
ref|NP_629196.1| fumarate hydratase class I [Streptomyces c... 709 0.0
ref|XP_782370.2| PREDICTED: similar to SJCHGC09380 protein ... 707 0.0
ref|ZP_02187346.1| Fumarate hydratase class I aerobic [alph... 707 0.0
ref|NP_905572.1| fumarate hydratase class I, anaerobic [Por... 706 0.0
ref|YP_631365.1| fumarate hydratase, class I [Myxococcus xa... 706 0.0
ref|YP_001234467.1| hydro-lyase, Fe-S type, tartrate/fumara... 705 0.0
ref|YP_001929009.1| fumarate hydratase class I anaerobic [P... 705 0.0
gb|AAW26769.1| SJCHGC09380 protein [Schistosoma japonicum] 705 0.0
ref|ZP_03878233.1| fumarase [Haliangium ochraceum DSM 14365... 702 0.0
ref|XP_001417167.1| predicted protein [Ostreococcus lucimar... 702 0.0
ref|ZP_02858786.1| hydro-lyase, Fe-S type, tartrate/fumarat... 702 0.0
ref|XP_847862.1| fumarate hydratase, putative [Leishmania m... 700 0.0
ref|NP_824394.1| fumarate hydratase class I [Streptomyces a... 699 0.0
ref|XP_001745789.1| predicted protein [Monosiga brevicollis... 699 0.0
ref|YP_768288.1| utative fumarate hydratase class I, aerobi... 699 0.0
ref|ZP_03815532.1| fumarase [Actinosynnema mirum DSM 43827]... 698 0.0
ref|XP_814517.1| fumarate hydratase, putative [Trypanosoma ... 698 0.0
ref|XP_001466723.1| fumarate hydratase [Leishmania infantum... 698 0.0
ref|XP_001566537.1| fumarate hydratase, putative [Leishmani... 697 0.0
gb|ABF20402.1| fumarate hydratase [Leishmania tropica] 697 0.0
ref|ZP_03859476.1| fumarase [Kribbella flavida DSM 17836] >... 697 0.0
gb|ABF20401.1| fumarate hydratase [Leishmania infantum] 697 0.0
gb|ABF20395.1| fumarate hydratase [Leishmania infantum] 697 0.0
ref|ZP_02297379.1| hydro-lyase, Fe-S type, tartrate/fumarat... 696 0.0
gb|ABF20376.1| fumarate hydratase [Leishmania infantum] 696 0.0
ref|YP_001438056.1| hypothetical protein ESA_01967 [Enterob... 696 0.0
ref|ZP_03922648.1| fumarate hydratase class I [Mobiluncus c... 695 0.0
gb|ACO63163.1| putative fumarate hydratase class1-malate <=... 695 0.0
ref|XP_844042.1| fumarate hydratase, putative [Trypanosoma ... 695 0.0
ref|XP_821204.1| fumarate hydratase, putative [Trypanosoma ... 695 0.0
ref|YP_001335177.1| fumarase A (fumarate hydratase class I)... 695 0.0
gb|ABF20398.1| fumarate hydratase [Leishmania donovani arch... 695 0.0
ref|YP_001335207.1| fumarase B (fumarate hydratase class I)... 693 0.0
ref|YP_001177280.1| hydro-lyase, Fe-S type, tartrate/fumara... 693 0.0
ref|YP_001005156.1| fumarate hydratase, class I [Yersinia e... 692 0.0
ref|YP_001402228.1| fumarate hydratase, class I [Yersinia p... 692 0.0
ref|YP_001743642.1| fumarate hydratase [Escherichia coli SM... 692 0.0
ref|NP_756975.1| Fumarate hydratase class I, anaerobic [Esc... 692 0.0
ref|NP_707511.1| fumarase A, fumarate hydratase Class I; ae... 692 0.0
ref|XP_001696634.1| fumarate hydratase [Chlamydomonas reinh... 692 0.0
ref|NP_406801.1| fumarate hydratase, class I [Yersinia pest... 691 0.0
ref|NP_416129.1| fumarate hydratase (fumarase A), aerobic C... 691 0.0
ref|YP_689106.1| Fumarate hydratase class I, aerobic [Shige... 691 0.0
ref|ZP_00831475.1| COG1951: Tartrate dehydratase alpha subu... 691 0.0
ref|YP_001823993.1| putative fumarate hydratase class I [St... 691 0.0
gb|ABF20388.1| fumarate hydratase [Leishmania infantum] 691 0.0
ref|YP_310482.1| fumarase A [Shigella sonnei Ss046] >gi|752... 691 0.0
ref|ZP_00922444.1| COG1951: Tartrate dehydratase alpha subu... 691 0.0
ref|ZP_02072327.1| hypothetical protein BACUNI_03773 [Bacte... 691 0.0
ref|YP_001722124.1| hydro-lyase, Fe-S type, tartrate/fumara... 690 0.0
ref|YP_001746516.1| fumarate hydratase class I, anaerobic [... 690 0.0
ref|YP_403430.1| fumarase A [Shigella dysenteriae Sd197] >g... 689 0.0
ref|YP_001610994.1| hypothetical protein sce0357 [Sorangium... 689 0.0
ref|ZP_02437159.1| hypothetical protein BACSTE_03432 [Bacte... 689 0.0
ref|ZP_00825174.1| COG1951: Tartrate dehydratase alpha subu... 689 0.0
ref|YP_469892.1| fumarate hydratase class I protein [Rhizob... 689 0.0
gb|EEH92879.1| fumarate hydratase class I [Citrobacter sp. ... 689 0.0
ref|NP_288047.1| fumarase A = fumarate hydratase Class I; a... 689 0.0
ref|ZP_00822736.1| COG1951: Tartrate dehydratase alpha subu... 689 0.0
ref|YP_705834.1| fumarate hydratase class I [Rhodococcus sp... 688 0.0
ref|ZP_03833166.1| fumarate hydratase class I, aerobic [Pec... 688 0.0
ref|YP_313027.1| fumarase B [Shigella sonnei Ss046] >gi|752... 688 0.0
ref|YP_001726834.1| hydro-lyase, Fe-S type, tartrate/fumara... 687 0.0
ref|ZP_02904384.1| fumarate hydratase class I, anaerobic [E... 687 0.0
ref|ZP_03828861.1| fumarate hydratase class I, aerobic [Pec... 687 0.0
ref|YP_049013.1| fumarate hydratase class I, aerobic [Erwin... 687 0.0
ref|ZP_00925876.1| COG1951: Tartrate dehydratase alpha subu... 687 0.0
ref|YP_119417.1| putative fumarate hydratase [Nocardia farc... 687 0.0
ref|YP_001299156.1| anaerobic fumarate hydratase class I [B... 687 0.0
ref|NP_418546.1| anaerobic class I fumarate hydratase (fuma... 686 0.0
ref|ZP_02166775.1| Fumarate lyase:Fe-S type hydro-lyase tar... 686 0.0
ref|NP_697971.1| fumarate hydratase, class I [Brucella suis... 686 0.0
ref|ZP_03836673.1| fumarate hydratase class I, aerobic [Cit... 686 0.0
ref|NP_539933.1| FUMARATE HYDRATASE CLASS I, AEROBIC [Bruce... 686 0.0
ref|YP_410570.1| fumarase B [Shigella boydii Sb227] >gi|812... 686 0.0
ref|NP_313131.1| fumarase B [Escherichia coli O157:H7 str. ... 686 0.0
ref|ZP_02739706.1| fumarase B [Escherichia coli O157:H7 str... 686 0.0
ref|ZP_00722640.1| COG1951: Tartrate dehydratase alpha subu... 686 0.0
ref|ZP_02903194.1| fumarate hydratase [Escherichia albertii... 686 0.0
ref|YP_001176561.1| hydro-lyase, Fe-S type, tartrate/fumara... 685 0.0
ref|ZP_00835117.1| COG1951: Tartrate dehydratase alpha subu... 685 0.0
gb|AAA23827.1| anaerobic class I fumarase (EC 4.2.1.2) 685 0.0
ref|YP_097958.1| anaerobic fumarate hydratase class I [Bact... 685 0.0
ref|ZP_01547699.1| Fumarate lyase [Stappia aggregata IAM 12... 685 0.0
ref|YP_691399.1| Fumarate hydratase class I, anaerobic [Shi... 684 0.0
ref|YP_867134.1| hydro-lyases, Fe-S type, tartrate/fumarate... 684 0.0
gb|AAA97022.1| fumarase [Escherichia coli] 684 0.0
emb|CAM74591.1| Tartrate dehydratase alpha subunit/Fumarate... 684 0.0
ref|NP_709819.1| fumarase B, fumarate hydratase Class I [Sh... 684 0.0
ref|ZP_02424765.1| hypothetical protein ALIPUT_00893 [Alist... 684 0.0
ref|YP_001104025.1| fumarate hydratase class I [Saccharopol... 684 0.0
ref|YP_001592802.1| hydro-lyase, Fe-S type, tartrate/fumara... 684 0.0
ref|YP_001627633.1| hydro-lyase, Fe-S type, tartrate/fumara... 684 0.0
ref|YP_001453190.1| hypothetical protein CKO_01623 [Citroba... 683 0.0
emb|CAL51520.1| fumarate hydratase class I (ISS) [Ostreococ... 683 0.0
ref|NP_290755.1| fumarase B= fumarate hydratase Class I; an... 683 0.0
ref|ZP_02066092.1| hypothetical protein BACOVA_03087 [Bacte... 683 0.0
ref|ZP_02646500.1| hypothetical protein Senterenterica_1279... 682 0.0
ref|ZP_02561418.1| fumarase B [Salmonella enterica subsp. e... 682 0.0
ref|YP_001258929.1| fumarate hydratase, class I [Brucella o... 682 0.0
gb|EDT29778.1| fumarate hydratase class I, anaerobic (Fumar... 681 0.0
ref|YP_420694.1| Fumarate hydratase class I aerobic [Magnet... 681 0.0
ref|YP_001455261.1| hypothetical protein CKO_03749 [Citroba... 681 0.0
ref|YP_001161051.1| hydro-lyase, Fe-S type, tartrate/fumara... 680 0.0
ref|YP_001370770.1| hydro-lyase, Fe-S type, tartrate/fumara... 680 0.0
ref|ZP_01961337.1| hypothetical protein BACCAC_02968 [Bacte... 679 0.0
ref|ZP_00993841.1| fumarate hydratase class I [Janibacter s... 679 0.0
ref|NP_811169.1| fumarate hydratase class I, anaerobic [Bac... 679 0.0
ref|NP_463165.1| fumarase B [Salmonella typhimurium LT2] >g... 678 0.0
ref|ZP_02013449.1| hydro-lyase, Fe-S type, tartrate/fumarat... 678 0.0
ref|YP_001572321.1| hypothetical protein SARI_03347 [Salmon... 678 0.0
ref|ZP_02030648.1| hypothetical protein PARMER_00620 [Parab... 678 0.0
ref|YP_001193234.1| hydro-lyase, Fe-S type, tartrate/fumara... 677 0.0
ref|YP_846452.1| hydro-lyases, Fe-S type, tartrate/fumarate... 677 0.0
ref|ZP_03850894.1| fumarate hydratase [Chryseobacterium gle... 677 0.0
ref|YP_427293.1| tartrate dehydrogenase [Rhodospirillum rub... 677 0.0
ref|ZP_02685331.1| fumarase B [Salmonella enterica subsp. e... 677 0.0
ref|YP_001588077.1| hypothetical protein SPAB_01851 [Salmon... 677 0.0
ref|YP_001304100.1| fumarate hydratase class I, anaerobic [... 676 0.0
ref|NP_460429.1| fumarase A [Salmonella typhimurium LT2] >g... 676 0.0
ref|YP_216472.1| fumarase A (fumarate hydratase class I), a... 676 0.0
ref|YP_002767658.1| fumarate hydratase class I [Rhodococcus... 675 0.0
ref|ZP_02345313.1| hypothetical protein Sentente_13804 [Sal... 675 0.0
ref|ZP_02649455.1| hypothetical protein Sententeric_00485 [... 675 0.0
ref|YP_001878733.1| hydro-lyase, Fe-S type, tartrate/fumara... 675 0.0
ref|YP_219166.1| fumarase B (fumarate hydratase class I), a... 675 0.0
ref|YP_002783153.1| fumarate hydratase class I [Rhodococcus... 674 0.0
ref|YP_001840478.1| Fumarate hydratase class I, aerobic (Fu... 674 0.0
ref|YP_001480245.1| hydro-lyase, Fe-S type, tartrate/fumara... 674 0.0
ref|YP_150641.1| Fumarate hydratase class I, aerobic [Salmo... 674 0.0
ref|ZP_01909505.1| fumarate hydratase, class I [Plesiocysti... 674 0.0
ref|ZP_02351328.1| hypothetical protein Sententeri_15956 [S... 674 0.0
ref|ZP_02665916.1| Fumarate hydratase class I, aerobic [Sal... 674 0.0
ref|YP_001539419.1| hydro-lyase, Fe-S type, tartrate/fumara... 674 0.0
gb|EEJ99437.1| fumarase [Tsukamurella paurometabola DSM 20162] 673 0.0
ref|ZP_02564600.1| hypothetical protein Senten_02232 [Salmo... 673 0.0
ref|ZP_02700852.1| fumarate hydratase class I [Salmonella e... 673 0.0
ref|ZP_02346001.1| fumarate hydratase class I [Salmonella e... 673 0.0
ref|NP_949213.1| fumarate hydratase, class I [Rhodopseudomo... 673 0.0
ref|NP_458599.1| fumarate hydratase class I [Salmonella ent... 673 0.0
ref|YP_153174.1| fumarate hydratase class I [Salmonella ent... 673 0.0
ref|ZP_03925560.1| fumarate hydratase class I [Actinomyces ... 673 0.0
ref|ZP_02565856.1| fumarate hydratase class I [Salmonella e... 672 0.0
ref|YP_001591410.1| hypothetical protein SPAB_05302 [Salmon... 672 0.0
ref|ZP_02668652.1| hypothetical protein Senterienterica_188... 672 0.0
ref|NP_456064.1| Fumarate hydratase class I, aerobic [Salmo... 672 0.0
ref|YP_487367.1| Fumarate hydratase, class I [Rhodopseudomo... 671 0.0
ref|YP_001570548.1| hypothetical protein SARI_01510 [Salmon... 671 0.0
ref|ZP_02559788.1| Fumarate hydratase class I, aerobic [Sal... 670 0.0
ref|ZP_02349309.1| fumarate hydratase class I [Salmonella e... 670 0.0
ref|YP_001241352.1| fumarase A (fumarate hydratase class I)... 670 0.0
ref|ZP_02302798.1| hydro-lyase, Fe-S type, tartrate/fumarat... 669 0.0
ref|YP_780500.1| hydro-lyases, Fe-S type, tartrate/fumarate... 669 0.0
ref|ZP_02338828.1| hypothetical protein Sentent_08256 [Salm... 669 0.0
ref|YP_001206931.1| fumarase A (fumarate hydratase class I)... 669 0.0
ref|YP_531414.1| hydro-lyases, Fe-S type, tartrate/fumarate... 668 0.0
ref|ZP_01774525.1| hydro-lyase, Fe-S type, tartrate/fumarat... 667 0.0
ref|YP_001833973.1| hydro-lyase, Fe-S type, tartrate/fumara... 667 0.0
ref|NP_772436.1| Fumarate hydratase class I [Bradyrhizobium... 667 0.0
ref|YP_568845.1| hydro-lyases, Fe-S type, tartrate/fumarate... 666 0.0
ref|ZP_03838974.1| hypothetical protein CATC2_23480 [Citrob... 664 0.0
ref|YP_922266.1| hydro-lyases, Fe-S type, tartrate/fumarate... 663 0.0
gb|EEH96136.1| conserved hypothetical protein [Citrobacter ... 663 0.0
ref|ZP_02959159.1| hypothetical protein PROSTU_00957 [Provi... 662 0.0
ref|ZP_02981625.1| hydro-lyase, Fe-S type, tartrate/fumarat... 662 0.0
ref|ZP_00832031.1| COG1951: Tartrate dehydratase alpha subu... 661 0.0
ref|YP_001907860.1| Fumarase A [Erwinia tasmaniensis] >gi|1... 660 0.0
ref|YP_001601151.1| Fumarate hydratase class [Gluconacetoba... 660 0.0
ref|YP_679867.1| fumarate hydratase, class I [Cytophaga hut... 659 0.0
ref|ZP_01876100.1| fumarate hydratase, class I [Lentisphaer... 659 0.0
ref|YP_001008178.1| fumarate hydratase class I, anaerobic [... 655 0.0
ref|ZP_01733811.1| fumarate hydratase, class I [Flavobacter... 654 0.0
ref|ZP_00831149.1| COG1951: Tartrate dehydratase alpha subu... 654 0.0
ref|YP_385514.1| Fe-S type hydro-lyase tartrate/fumarate al... 651 0.0
ref|NP_968997.1| fumarate hydratase, class I [Bdellovibrio ... 647 0.0
ref|YP_001380232.1| hydro-lyase, Fe-S type, tartrate/fumara... 647 0.0
ref|ZP_01312990.1| hydro-lyases, Fe-S type, tartrate/fumara... 644 0.0
ref|YP_001817521.1| hydro-lyase, Fe-S type, tartrate/fumara... 644 0.0
ref|YP_465275.1| fumarase [Anaeromyxobacter dehalogenans 2C... 642 0.0
ref|ZP_02132117.1| hydro-lyase, Fe-S type, tartrate/fumarat... 642 0.0
ref|ZP_02174352.1| hydro-lyase, Fe-S type, tartrate/fumarat... 640 0.0
ref|ZP_02323626.1| hydro-lyase, Fe-S type, tartrate/fumarat... 639 0.0
ref|YP_001230419.1| hydro-lyase, Fe-S type, tartrate/fumara... 635 e-180
ref|NP_952048.1| fumarate hydratase, class I [Geobacter sul... 632 e-179
ref|XP_763097.1| fumarate hydratase [Theileria parva strain... 630 e-179
ref|ZP_02753357.1| fumarase A [Escherichia coli O157:H7 str... 630 e-178
ref|YP_900437.1| hydro-lyases, Fe-S type, tartrate/fumarate... 629 e-178
ref|YP_001453977.1| hypothetical protein CKO_02424 [Citroba... 626 e-177
ref|YP_001742833.1| hydro-lyase, Fe-S type, tartrate/fumara... 624 e-177
ref|XP_954791.1| Fumarate hydratase class I, putative [Thei... 624 e-177
ref|ZP_00380865.1| COG1951: Tartrate dehydratase alpha subu... 623 e-176
ref|NP_286449.1| putative fumarate hydratase [Escherichia c... 622 e-176
ref|YP_001571219.1| hypothetical protein SARI_02205 [Salmon... 621 e-176
gb|EEH92162.1| conserved hypothetical protein [Citrobacter ... 619 e-175
ref|XP_001608904.1| fumarate hydratase, putative [Babesia b... 617 e-175
ref|ZP_03835909.1| hypothetical protein CATC2_07906 [Citrob... 616 e-174
gb|EEH57583.1| predicted protein [Micromonas pusilla CCMP1545] 614 e-174
ref|YP_001528580.1| hydro-lyase, Fe-S type, tartrate/fumara... 604 e-171
ref|XP_001734600.1| fumarate hydratase class I, anaerobic, ... 601 e-170
ref|YP_887304.1| fumarate hydratase class I, anaerobic [Myc... 590 e-166
ref|XP_745408.1| fumarate hydratase [Plasmodium chabaudi ch... 571 e-161
ref|XP_678794.1| fumarate hydratase [Plasmodium berghei str... 557 e-157
ref|XP_725604.1| fumarate hydratase class I [Plasmodium yoe... 551 e-155
ref|XP_001352143.1| fumarate hydratase, putative [Plasmodiu... 537 e-151
ref|ZP_02956977.1| hydro-lyase, Fe-S type, tartrate/fumarat... 529 e-148
ref|ZP_00053808.1| COG1951: Tartrate dehydratase alpha subu... 508 e-142
ref|ZP_02333680.1| fumarate hydratase, class I [Yersinia pe... 478 e-133
ref|XP_001614810.1| fumarate hydratase, putative [Plasmodiu... 439 e-121
ref|XP_001740036.1| serine acetyltransferase, putative [Ent... 265 6e-69
ref|ZP_01594892.1| hydro-lyases, Fe-S type, tartrate/fumara... 257 2e-66
gb|ABF71064.1| fumarase A [Enterobacter cloacae] 238 8e-61
ref|XP_650763.2| fumarate hydratase class I, anaerobic, put... 221 1e-55
ref|XP_001913833.1| fumarate hydratase class I, anaerobic, ... 210 3e-52
ref|ZP_01627953.1| fumarate hydratase, class I, putative [m... 188 1e-45
ref|ZP_01227738.1| putative fumarate hydratase [Aurantimona... 186 6e-45
ref|ZP_01043530.1| Fumarase B [Idiomarina baltica OS145] >g... 186 7e-45
ref|YP_350180.1| Fe-S type hydro-lyase tartrate/fumarate al... 182 6e-44
ref|ZP_01552148.1| putative fumarate hydratase, class I [Me... 182 9e-44
ref|NP_106657.1| fumarate hydratase, class I [Mesorhizobium... 181 2e-43
ref|YP_261882.1| fumarate hydratase, class I, putative [Pse... 180 2e-43
emb|CAD31582.1| PROBABLE FUMARATE HYDRATASE CLASS I FUMARAS... 180 3e-43
ref|ZP_00417946.1| Fe-S type hydro-lyases tartrate/fumarate... 180 3e-43
ref|YP_002800960.1| fumarate hydratase, class I [Azotobacte... 180 3e-43
ref|YP_997962.1| hydro-lyases, Fe-S type, tartrate/fumarate... 179 4e-43
ref|YP_001858166.1| hydro-lyase, Fe-S type, tartrate/fumara... 179 4e-43
ref|YP_001142090.1| fumarate hydratase, class I [Aeromonas ... 179 5e-43
ref|XP_735578.1| hypothetical protein PC300393.00.0 [Plasmo... 179 5e-43
ref|ZP_01077265.1| probable fumarase [Marinomonas sp. MED12... 179 5e-43
ref|YP_001352570.1| fumarate hydratase, class I [Janthinoba... 179 5e-43
ref|YP_001532769.1| hydro-lyase, Fe-S type, tartrate/fumara... 179 6e-43
ref|YP_606854.1| fumarate hydratase, class I [Pseudomonas e... 179 7e-43
ref|YP_959303.1| hydro-lyases, Fe-S type, tartrate/fumarate... 179 7e-43
ref|YP_523831.1| hydro-lyases, Fe-S type, tartrate/fumarate... 178 1e-42
ref|YP_001266281.1| hydro-lyase, Fe-S type, tartrate/fumara... 177 2e-42
ref|ZP_01892241.1| Tartrate dehydratase alpha subunit/Fumar... 177 2e-42
ref|NP_743058.1| fumarate hydratase, class I [Pseudomonas p... 177 2e-42
ref|YP_166739.1| fumarate hydratase, class I, putative [Sil... 177 3e-42
ref|YP_856949.1| fumarate hydratase, class I [Aeromonas hyd... 177 3e-42
ref|YP_969853.1| hydro-lyases, Fe-S type, tartrate/fumarate... 176 3e-42
ref|ZP_02885805.1| hydro-lyase, Fe-S type, tartrate/fumarat... 176 3e-42
ref|YP_001629387.1| Fumarate hydratase class I anaerobic [B... 176 4e-42
ref|YP_001171684.1| probable fumarase [Pseudomonas stutzeri... 176 4e-42
ref|ZP_01522381.1| hydro-lyases, Fe-S type, tartrate/fumara... 176 4e-42
ref|YP_237099.1| Fe-S type hydro-lyase tartrate/fumarate al... 176 5e-42
ref|YP_001350238.1| fumarate hydratase, class I [Pseudomona... 176 5e-42
ref|NP_794095.1| fumarate hydratase, class I, putative [Pse... 176 5e-42
ref|YP_276169.1| fumarate hydratase, class I, putative [Pse... 175 8e-42
ref|YP_001747874.1| hydro-lyase, Fe-S type, tartrate/fumara... 175 8e-42
ref|YP_943344.1| fumarate hydratase [Psychromonas ingrahami... 175 8e-42
ref|YP_001670678.1| hydro-lyase, Fe-S type, tartrate/fumara... 175 8e-42
ref|YP_001020579.1| putative fumarate hydratase [Methylibiu... 175 9e-42
ref|YP_045286.1| fumarate hydratase [Acinetobacter sp. ADP1... 175 9e-42
ref|YP_548874.1| hydro-lyases, Fe-S type, tartrate/fumarate... 175 1e-41
ref|YP_001895052.1| hydro-lyase, Fe-S type, tartrate/fumara... 174 1e-41
ref|YP_130595.1| Putative fumarate hydratase, class I [Phot... 174 1e-41
ref|YP_110392.1| fumarate hydratase [Burkholderia pseudomal... 174 1e-41
ref|YP_001188750.1| hydro-lyase, Fe-S type, tartrate/fumara... 174 1e-41
ref|NP_885804.1| putative fumarate hydratase [Bordetella pa... 174 2e-41
ref|YP_001674474.1| hydro-lyase, Fe-S type, tartrate/fumara... 174 2e-41
ref|NP_253023.1| probable fumarase [Pseudomonas aeruginosa ... 174 2e-41
ref|ZP_01364002.1| hypothetical protein PaerPA_01001105 [Ps... 174 2e-41
ref|ZP_02000730.1| fumarate hydratase, class I, anaerobic [... 174 2e-41
ref|ZP_01953547.1| fumarate hydratase, class I, putative [V... 174 3e-41
ref|YP_903986.1| hydro-lyases, Fe-S type, tartrate/fumarate... 173 3e-41
ref|YP_156087.1| Fumarase B [Idiomarina loihiensis L2TR] >g... 173 3e-41
ref|YP_001155919.1| hydro-lyase, Fe-S type, tartrate/fumara... 173 3e-41
ref|ZP_01705003.1| hydro-lyases, Fe-S type, tartrate/fumara... 173 3e-41
ref|ZP_01330957.1| hypothetical protein BpseS_03000801 [Bur... 173 3e-41
ref|YP_002762793.1| fumarate hydratase class I [Gemmatimona... 173 3e-41
ref|YP_001708158.1| fumarate hydratase [Acinetobacter bauma... 173 3e-41
ref|YP_001563677.1| hydro-lyase, Fe-S type, tartrate/fumara... 173 4e-41
ref|YP_001181879.1| hydro-lyase, Fe-S type, tartrate/fumara... 173 4e-41
ref|YP_961604.1| hydro-lyases, Fe-S type, tartrate/fumarate... 173 4e-41
ref|YP_983103.1| hydro-lyases, Fe-S type, tartrate/fumarate... 173 4e-41
ref|ZP_01134586.1| fumarate hydratase, class I [Pseudoalter... 172 5e-41
ref|ZP_02405688.1| fumarate hydratase, class I [Burkholderi... 172 5e-41
ref|YP_106350.1| hydro-lyase, Fe-S type, tartrate/fumarate ... 172 5e-41
ref|YP_001265147.1| hydro-lyase, Fe-S type, tartrate/fumara... 172 5e-41
ref|ZP_02492649.1| fumarate hydratase [Burkholderia pseudom... 172 6e-41
ref|ZP_01104763.1| fumarate hydratase, class I, anaerobic [... 172 6e-41
ref|YP_557895.1| tartrate/fumarate Fe-S type hydro-lyases [... 172 6e-41
ref|YP_001083537.1| fumarate hydratase [Acinetobacter bauma... 172 6e-41
ref|ZP_01740845.1| putative fumarate hydratase [Rhodobacter... 172 7e-41
ref|ZP_02859309.1| hydro-lyase, Fe-S type, tartrate/fumarat... 172 7e-41
ref|ZP_00991791.1| fumarate hydratase, class I [Vibrio sple... 172 8e-41
ref|YP_001219555.1| fumarate hydratase, class I [Candidatus... 172 8e-41
gb|ABL01759.1| unknown [Salmonella enterica subsp. enterica... 172 8e-41
ref|YP_743242.1| fumarase [Alkalilimnicola ehrlichei MLHE-1... 171 1e-40
ref|YP_001579270.1| hydro-lyase, Fe-S type, tartrate/fumara... 171 1e-40
ref|YP_001899668.1| hydro-lyase, Fe-S type, tartrate/fumara... 171 1e-40
ref|YP_001341191.1| hydro-lyase, Fe-S type, tartrate/fumara... 171 1e-40
ref|ZP_02365109.1| hydro-lyases, Fe-S type, tartrate/fumara... 171 1e-40
ref|YP_562918.1| hydro-lyases, Fe-S type, tartrate/fumarate... 171 1e-40
>ref|XP_828580.1| fumarate hydratase class I [Trypanosoma brucei TREU927]
gb|EAN79468.1| fumarate hydratase class I, putative [Trypanosoma brucei]
Length = 555
Score = 1155 bits (2988), Expect = 0.0, Method: Composition-based stats.
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAG 60
MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAG
Sbjct: 1 MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAG 60
Query: 61 LTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQ 120
LTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQ
Sbjct: 61 LTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQ 120
Query: 121 DTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPA 180
DTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPA
Sbjct: 121 DTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPA 180
Query: 181 QIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPP 240
QIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPP
Sbjct: 181 QIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPP 240
Query: 241 YHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGM 300
YHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGM
Sbjct: 241 YHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGM 300
Query: 301 GAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKY 360
GAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKY
Sbjct: 301 GAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKY 360
Query: 361 LPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREML 420
LPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREML
Sbjct: 361 LPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREML 420
Query: 421 ENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
ENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG
Sbjct: 421 ENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
Query: 481 NRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAF 540
NRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAF
Sbjct: 481 NRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAF 540
Query: 541 IVVDDKGNDFFQQLR 555
IVVDDKGNDFFQQLR
Sbjct: 541 IVVDDKGNDFFQQLR 555
>ref|XP_804521.1| fumarate hydratase, putative [Trypanosoma cruzi strain CL Brener]
gb|EAN82670.1| fumarate hydratase, putative [Trypanosoma cruzi]
Length = 555
Score = 983 bits (2542), Expect = 0.0, Method: Composition-based stats.
Identities = 469/555 (84%), Positives = 507/555 (91%)
Query: 1 MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAG 60
MLRRS+ K+ PFK+VPL+PH+ H DT + L+TKDYVSVV PG GLPEIL+V+ G
Sbjct: 1 MLRRSAAALGKKAPVPFKYVPLIPHVSHDDTPFRLLTKDYVSVVRPGCGLPEILQVDVEG 60
Query: 61 LTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQ 120
L LAS A GDVQH LRPSHLASLR IF+DPEASDNDRFVALQL+KNANIAAAR+LPGCQ
Sbjct: 61 LAKLASEAFGDVQHLLRPSHLASLRRIFDDPEASDNDRFVALQLLKNANIAAARVLPGCQ 120
Query: 121 DTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPA 180
DTGTAI+AGYKGEQVFTNGD+ EALSRGV+ IYTTTNLRYSQNVPLTM+DEKNTG NLPA
Sbjct: 121 DTGTAIVAGYKGEQVFTNGDECEALSRGVYKIYTTTNLRYSQNVPLTMFDEKNTGSNLPA 180
Query: 181 QIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPP 240
QIDLYATKG EY F FVAKGGGSANKA+LFQETKSVLNPKSLR FLEEKI IGT+ACPP
Sbjct: 181 QIDLYATKGQEYNFMFVAKGGGSANKAYLFQETKSVLNPKSLRKFLEEKIGAIGTAACPP 240
Query: 241 YHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGM 300
YHMAVVVGGTSAEMT+K VKYASCKY D LPTKPDESKGY YRD EME +VMDIC N+GM
Sbjct: 241 YHMAVVVGGTSAEMTLKTVKYASCKYYDNLPTKPDESKGYAYRDTEMENVVMDICYNMGM 300
Query: 301 GAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKY 360
GAQFGGKYFAHDARVIR+PRHGASCPIGIGVSCSADRQALAKINKDGIW+E+LE DPAKY
Sbjct: 301 GAQFGGKYFAHDARVIRLPRHGASCPIGIGVSCSADRQALAKINKDGIWLEQLETDPAKY 360
Query: 361 LPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREML 420
LPE+TEDQLLK PPV IDL+MPM+KIRAELS++PVKTRLSL+GTIIVARD+AHARMREML
Sbjct: 361 LPEITEDQLLKTPPVNIDLSMPMEKIRAELSKYPVKTRLSLSGTIIVARDMAHARMREML 420
Query: 421 ENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
E KPLP+YIKNHPVYYAGPAK PE + SGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG
Sbjct: 421 EAGKPLPEYIKNHPVYYAGPAKCPEGMPSGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
Query: 481 NRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAF 540
NRS+ VT+ACKK+GGFYLGSIGGPAALLA DSIRKVEVLDM ELGMEAVWKIEVENFPAF
Sbjct: 481 NRSRAVTQACKKHGGFYLGSIGGPAALLAKDSIRKVEVLDMAELGMEAVWKIEVENFPAF 540
Query: 541 IVVDDKGNDFFQQLR 555
IV+DDKGNDFFQQL+
Sbjct: 541 IVLDDKGNDFFQQLK 555
>ref|XP_817100.1| fumarate hydratase, putative [Trypanosoma cruzi strain CL Brener]
gb|EAN95249.1| fumarate hydratase, putative [Trypanosoma cruzi]
Length = 555
Score = 983 bits (2540), Expect = 0.0, Method: Composition-based stats.
Identities = 469/555 (84%), Positives = 507/555 (91%)
Query: 1 MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAG 60
MLRRS+ K+ PFK+VPL+PH+ H DT L+TKDYVSVV PG G+PEIL+V+ G
Sbjct: 1 MLRRSAAALGKKAPVPFKYVPLIPHVSHDDTPLRLLTKDYVSVVRPGCGVPEILQVDVEG 60
Query: 61 LTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQ 120
LT LAS A GDVQH LRPSHLASLR IF+DPEASDNDRFVALQL+KNANIAAAR+LPGCQ
Sbjct: 61 LTRLASEAFGDVQHLLRPSHLASLRKIFDDPEASDNDRFVALQLLKNANIAAARVLPGCQ 120
Query: 121 DTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPA 180
DTGTAI+AGYKGEQVFTNGD+ EALSRGV+ IYTTTNLRYSQNVPLTM+DEKNTG NLPA
Sbjct: 121 DTGTAIVAGYKGEQVFTNGDECEALSRGVYKIYTTTNLRYSQNVPLTMFDEKNTGSNLPA 180
Query: 181 QIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPP 240
QIDLYATKG EY F FVAKGGGSANKA+LFQETKSVLNPKSLR FLEEKI IGT+ACPP
Sbjct: 181 QIDLYATKGQEYNFMFVAKGGGSANKAYLFQETKSVLNPKSLRKFLEEKIGAIGTAACPP 240
Query: 241 YHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGM 300
YHMAVVVGGTSAEMT+K VKYASCKY D LPTKPDESKGY YRD EME +VMDIC N+GM
Sbjct: 241 YHMAVVVGGTSAEMTLKTVKYASCKYYDNLPTKPDESKGYAYRDTEMENVVMDICYNMGM 300
Query: 301 GAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKY 360
GAQFGGKYFAHDARVIR+PRHGASCPIGIGVSCSADRQALAKINKDGIW+E+LE DPAKY
Sbjct: 301 GAQFGGKYFAHDARVIRLPRHGASCPIGIGVSCSADRQALAKINKDGIWLEQLETDPAKY 360
Query: 361 LPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREML 420
LPE+TEDQLLK PPV IDL+MPM+KIRAELS++PVKTRLSL+GTIIVARD+AHARMREML
Sbjct: 361 LPEITEDQLLKTPPVNIDLSMPMEKIRAELSKYPVKTRLSLSGTIIVARDMAHARMREML 420
Query: 421 ENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
E KPLP+YIKNHPVYYAGPAK PE + SGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG
Sbjct: 421 EAGKPLPEYIKNHPVYYAGPAKCPEGMPSGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
Query: 481 NRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAF 540
NRS+ VT+ACKK+GGFYLGSIGGPAALLA DSIRKVEVLDM ELGMEAVWKIEVENFPAF
Sbjct: 481 NRSRAVTQACKKHGGFYLGSIGGPAALLAKDSIRKVEVLDMAELGMEAVWKIEVENFPAF 540
Query: 541 IVVDDKGNDFFQQLR 555
IV+DDKGNDFFQQL+
Sbjct: 541 IVLDDKGNDFFQQLK 555
>ref|XP_001565298.1| fumarate hydratase, putative [Leishmania braziliensis
MHOM/BR/75/M2904]
emb|CAM42207.1| fumarate hydratase, putative [Leishmania braziliensis]
Length = 549
Score = 887 bits (2292), Expect = 0.0, Method: Composition-based stats.
Identities = 412/538 (76%), Positives = 481/538 (89%)
Query: 17 FKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F FVPL+ + HK+T+Y L+ KD+VSVV PGAGLPE+LKV+ A LTLL+S A D++H +
Sbjct: 12 FNFVPLVSKVSHKETKYRLLAKDHVSVVQPGAGLPEMLKVDPAALTLLSSVAFDDIEHLM 71
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
R SHLASLR IF+DPEASDND+FVALQL+KNANI++AR+LPGCQDTGTAII+G++GEQVF
Sbjct: 72 RSSHLASLRKIFDDPEASDNDKFVALQLLKNANISSARLLPGCQDTGTAIISGHRGEQVF 131
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFF 196
G++EEALSRGV+ I+ NLRYSQNVPL+MYDEKNTG NLPAQIDLYATKG EY F F
Sbjct: 132 VLGNEEEALSRGVYDIFQERNLRYSQNVPLSMYDEKNTGTNLPAQIDLYATKGMEYSFLF 191
Query: 197 VAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTM 256
VAKGGGSANK+FL QE+KSVLNPKSLR FL+EK++ GTSACPPYH+AVV+GGTSAEMTM
Sbjct: 192 VAKGGGSANKSFLLQESKSVLNPKSLRKFLKEKLAMFGTSACPPYHIAVVIGGTSAEMTM 251
Query: 257 KAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVI 316
+ VK+ASC Y D+L TKPD GYT+RDLE+E+ V++IC+NIGMGAQFGGKY+AHDARVI
Sbjct: 252 RMVKHASCHYYDDLITKPDMKTGYTFRDLELEKEVLEICQNIGMGAQFGGKYYAHDARVI 311
Query: 317 RMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVK 376
RMPRHGASCPIGIGVSCSADRQAL KINKDG+W+E LEM+P+++LP+V ED+LLK PPV+
Sbjct: 312 RMPRHGASCPIGIGVSCSADRQALGKINKDGVWLEVLEMEPSRFLPDVKEDELLKTPPVE 371
Query: 377 IDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVY 436
++LN PM ++ ELS+HPVKTRLSLTGTI+VARD AHARMREMLE KPLP Y+K+HPVY
Sbjct: 372 VNLNRPMSEVLQELSKHPVKTRLSLTGTIVVARDSAHARMREMLEAGKPLPQYMKDHPVY 431
Query: 437 YAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGF 496
YAGPAK P+ L SGSFGPTTAGRMDPFVDLFQ+ GGS VMLAKGNRSK VTEACKK+GGF
Sbjct: 432 YAGPAKTPDGLPSGSFGPTTAGRMDPFVDLFQSLGGSMVMLAKGNRSKHVTEACKKHGGF 491
Query: 497 YLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQL 554
YLGSIGGPAA+LA D+I+KVE LDM++LGMEAVWKIEV+NFPAFIVVDDKGNDFFQQL
Sbjct: 492 YLGSIGGPAAVLAQDAIKKVECLDMKDLGMEAVWKIEVQNFPAFIVVDDKGNDFFQQL 549
>ref|XP_001683549.1| fumarate hydratase, putative [Leishmania major]
emb|CAJ04118.1| fumarate hydratase, putative [Leishmania major]
Length = 549
Score = 887 bits (2292), Expect = 0.0, Method: Composition-based stats.
Identities = 418/554 (75%), Positives = 486/554 (87%), Gaps = 5/554 (0%)
Query: 1 MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAG 60
MLRR AP A F FVPL+ + HK+T+Y L+TKDYVSVV PGAGLPE+L+V+ A
Sbjct: 1 MLRR----LAPLLAE-FNFVPLVSKVSHKETKYRLLTKDYVSVVQPGAGLPEMLRVDPAA 55
Query: 61 LTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQ 120
LTLL+S A DV+H LR SHL SLR IF+DPEASDND+FVALQL+KNANI++AR+LPGCQ
Sbjct: 56 LTLLSSTAFDDVEHLLRSSHLMSLRKIFDDPEASDNDKFVALQLLKNANISSARLLPGCQ 115
Query: 121 DTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPA 180
DTGTAIIAGY+G+QVF G+DEEALSRGV+ I+ N RYSQNVPL+MYDEKNTG NLPA
Sbjct: 116 DTGTAIIAGYRGDQVFVPGNDEEALSRGVYDIFQKRNFRYSQNVPLSMYDEKNTGTNLPA 175
Query: 181 QIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPP 240
QIDLYA+KG EY F FVAKGGGSANK+FL QETKSVLNPKSLRNFL+EK++ GTSACPP
Sbjct: 176 QIDLYASKGMEYSFMFVAKGGGSANKSFLLQETKSVLNPKSLRNFLKEKLAMFGTSACPP 235
Query: 241 YHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGM 300
YH+AVV+GGTSAEMTMK +KYASC Y D+L TKPD GYT+RDLE+E+ V+ +C+NIGM
Sbjct: 236 YHVAVVIGGTSAEMTMKVLKYASCHYYDDLITKPDMKTGYTFRDLELEEEVLKVCQNIGM 295
Query: 301 GAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKY 360
GAQFGGKY+AHD RVIRMPRHGASCPIGIGVSCSADRQAL KINKDG+W+E+LEM+P++Y
Sbjct: 296 GAQFGGKYYAHDVRVIRMPRHGASCPIGIGVSCSADRQALGKINKDGVWLEELEMEPSQY 355
Query: 361 LPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREML 420
LP++ ED+LLK P V ++LN PM ++ ELS+HPV+TRLSLTGTIIVARD AHARMREML
Sbjct: 356 LPDLKEDELLKTPAVMVNLNRPMPEVLQELSKHPVRTRLSLTGTIIVARDSAHARMREML 415
Query: 421 ENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
E KPLP Y+K HPVYYAGPAK+P+ L SGSFGPTTAGRMDPFVDLFQ++GGS VMLAKG
Sbjct: 416 EAGKPLPQYMKEHPVYYAGPAKQPDGLPSGSFGPTTAGRMDPFVDLFQSHGGSMVMLAKG 475
Query: 481 NRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAF 540
NRSK+VT+AC KYGGFYLGSIGGPAA+LA ++I+KVE LDM++LGMEAVW+IEVENFPAF
Sbjct: 476 NRSKQVTKACHKYGGFYLGSIGGPAAVLAQNAIKKVECLDMKDLGMEAVWRIEVENFPAF 535
Query: 541 IVVDDKGNDFFQQL 554
IVVDDKGNDFF+QL
Sbjct: 536 IVVDDKGNDFFEQL 549
>gb|EEJ97739.1| fumarase [Thermomonospora curvata DSM 43183]
Length = 546
Score = 726 bits (1873), Expect = 0.0, Method: Composition-based stats.
Identities = 353/535 (65%), Positives = 432/535 (80%), Gaps = 5/535 (0%)
Query: 17 FKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F + LLP +TEY L+T D +S + AG L+VE L +L A+ D+ H L
Sbjct: 4 FSYTDLLP-TGPDETEYRLLTTDGISTLE--AGGRTFLQVEPEVLRMLTETAMRDIAHLL 60
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
RPSHL LR+I +DPEAS NDRFVAL L+KNANIAAA +LP CQDTGTAI+ G +G+ V
Sbjct: 61 RPSHLQQLRNILDDPEASPNDRFVALDLLKNANIAAAGVLPMCQDTGTAIVMGKRGQHVL 120
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFF 196
T+G DEE +SRGV+ YT NLRYSQ PLTM++EKNTG NLPAQI+LYAT G Y+F F
Sbjct: 121 TDGRDEEHISRGVYDAYTKLNLRYSQMAPLTMWEEKNTGNNLPAQIELYATAGDSYKFLF 180
Query: 197 VAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTM 256
+AKGGGSANK+FL+QETK+VLNPK + FLEEKI ++GT+ACPPYH+A+VVGGTSAE +
Sbjct: 181 MAKGGGSANKSFLYQETKAVLNPKRMMAFLEEKIRSLGTAACPPYHLAIVVGGTSAEYAL 240
Query: 257 KAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVI 316
K KYAS +YLD LPT S G+ +RDLEME+ V+++ RN+G+GAQFGGKYF HD RV+
Sbjct: 241 KVAKYASARYLDGLPTSGSMS-GHGFRDLEMERQVLELTRNLGIGAQFGGKYFCHDVRVV 299
Query: 317 RMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVK 376
R+PRHGASCP+ I VSCSADRQALAKI +G+++E+LE DPA++LP+ T ++ L V+
Sbjct: 300 RLPRHGASCPVAIAVSCSADRQALAKITPEGVFLEQLETDPARFLPDTTAEE-LGGEVVR 358
Query: 377 IDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVY 436
IDLN PMD+IRAELS++PVKTRLSLTG ++VARDIAHA+++E L+ +P+P Y+++H VY
Sbjct: 359 IDLNRPMDEIRAELSKYPVKTRLSLTGPLVVARDIAHAKIKERLDAGEPMPQYMRDHAVY 418
Query: 437 YAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGF 496
YAGPAK PE ASGSFGPTTAGRMD +V+ FQA GGS+VMLAKGNRS++VTEACKKYGGF
Sbjct: 419 YAGPAKTPEGYASGSFGPTTAGRMDSYVEQFQAAGGSYVMLAKGNRSRQVTEACKKYGGF 478
Query: 497 YLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
YLGSIGGPAA LA D I+KVEVL+ ELGMEAVWKIEVE+FPAFIVVDDKGNDFF
Sbjct: 479 YLGSIGGPAARLAQDCIKKVEVLEYPELGMEAVWKIEVEDFPAFIVVDDKGNDFF 533
>ref|YP_745628.1| fumarate hydratase [Granulibacter bethesdensis CGDNIH1]
gb|ABI62705.1| fumarate hydratase [Granulibacter bethesdensis CGDNIH1]
Length = 550
Score = 714 bits (1842), Expect = 0.0, Method: Composition-based stats.
Identities = 355/549 (64%), Positives = 424/549 (77%), Gaps = 10/549 (1%)
Query: 11 PKSA-PPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAI 69
P +A P F + P+ P L H +T + + + V IL + LT LA A
Sbjct: 6 PNAAFPGFAYSPMFP-LTHDETVWRKLDIGGLRVSEHEG--RRILHIAPEALTELARTAF 62
Query: 70 GDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAG 129
DV H LRP+HLA LR I +DPEAS NDRFVAL L+KNANIAA +LP CQDTGTAI+ G
Sbjct: 63 HDVAHLLRPAHLAQLRRILDDPEASANDRFVALDLLKNANIAAGGVLPMCQDTGTAIVFG 122
Query: 130 YKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKG 189
KG+ V+ GD+EEALS GVH YT TNLRYSQ PLTMY+EKNTG NLP Q D+ A G
Sbjct: 123 KKGQHVWVEGDEEEALSLGVHRTYTETNLRYSQMAPLTMYEEKNTGNNLPVQFDILAVPG 182
Query: 190 C----EYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAV 245
E++ FVAKGGGSANK FLFQET++VL+P+ L FLE KI T+GTSACPPYH+A+
Sbjct: 183 GHHADEFQLMFVAKGGGSANKTFLFQETRAVLSPEKLLPFLETKIRTLGTSACPPYHLAI 242
Query: 246 VVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFG 305
V+GGTSAE T+K VK AS K+LD LPT+ D + G+ +RDLE+EQ V+++ R+IG+GAQFG
Sbjct: 243 VIGGTSAETTLKTVKLASTKWLDTLPTQGDMT-GHAFRDLELEQQVLELTRSIGIGAQFG 301
Query: 306 GKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVT 365
GKYF HD RV+R+PRHGAS PI IGVSCSADRQ AKI +G+++E+LE DPA++LPE T
Sbjct: 302 GKYFCHDVRVVRLPRHGASLPIAIGVSCSADRQVRAKITPEGVFLEQLETDPARFLPEAT 361
Query: 366 EDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKP 425
+D +L V+IDLN PMD+IRA LS+HPVKTRLSLTGT++VARDIAHA++ E LE +
Sbjct: 362 DD-ILGGEVVRIDLNRPMDEIRAALSKHPVKTRLSLTGTVVVARDIAHAKLAERLEAGEG 420
Query: 426 LPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKR 485
LPDYIKNHPVYYAGPAK P+ + +GSFGPTTAGRMD +VD FQ GGSFVMLAKGNRSK
Sbjct: 421 LPDYIKNHPVYYAGPAKTPDGMPTGSFGPTTAGRMDSYVDAFQKAGGSFVMLAKGNRSKA 480
Query: 486 VTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDD 545
V +ACK YGGFYLGS+GGPAA LA D IRKVEVL+ ELGMEAVWKIEVE+FPAFIV+DD
Sbjct: 481 VRDACKTYGGFYLGSVGGPAARLAQDCIRKVEVLEYPELGMEAVWKIEVEDFPAFIVIDD 540
Query: 546 KGNDFFQQL 554
KGNDFF+ L
Sbjct: 541 KGNDFFEGL 549
>ref|NP_629196.1| fumarate hydratase class I [Streptomyces coelicolor A3(2)]
emb|CAC05889.1| fumarate hydratase class I [Streptomyces coelicolor A3(2)]
Length = 558
Score = 709 bits (1831), Expect = 0.0, Method: Composition-based stats.
Identities = 348/539 (64%), Positives = 424/539 (78%), Gaps = 5/539 (0%)
Query: 15 PPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQH 74
P F + LLP T Y LVT + V+ A LKVE L LA A+ D+QH
Sbjct: 5 PEFAYTDLLPQ-GEDTTPYRLVTAEGVATFE--ADGRTFLKVEPEALRKLAEEAVHDIQH 61
Query: 75 FLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQ 134
+LRP+HLA LR I +DPEAS ND+FVAL L+KNANIAAA +LP CQDTGTAI+ G +G+
Sbjct: 62 YLRPAHLAQLRRIIDDPEASGNDKFVALDLLKNANIAAAGVLPMCQDTGTAIVMGKRGQN 121
Query: 135 VFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEF 194
V T G DEEALSRG++ Y NLRYSQ PLTM++EKNTG NLPAQI+LYAT G Y+F
Sbjct: 122 VLTEGGDEEALSRGIYDAYKNLNLRYSQMAPLTMWEEKNTGSNLPAQIELYATDGGAYKF 181
Query: 195 FFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEM 254
F+AKGGGSANK+FL+QETK+VLN S+ FLEEKI ++GT+ACPPYH+A+VVGGTSAE
Sbjct: 182 LFMAKGGGSANKSFLYQETKAVLNESSMMKFLEEKIRSLGTAACPPYHLAIVVGGTSAEY 241
Query: 255 TMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDAR 314
+K KYAS YLDE+P + E G+ +RD E+E+ V ++ + IG+GAQFGGKYF HD R
Sbjct: 242 ALKTAKYASAHYLDEIPAEGSE-LGHGFRDKELEEKVFELTQKIGIGAQFGGKYFCHDVR 300
Query: 315 VIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPP 374
V+R+PRHGASCP+ I VSCSADRQA+AKI +G+++E+LE DPA++LPE T++ L +
Sbjct: 301 VVRLPRHGASCPVAIAVSCSADRQAVAKITAEGVFLEQLETDPARFLPETTDEHLEEEGD 360
Query: 375 -VKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNH 433
VK+DLN PMD I AEL+RHPVKTRLSLTG ++VARDIAHA+++E L+ + +P Y+K+H
Sbjct: 361 VVKVDLNQPMDDILAELTRHPVKTRLSLTGPLVVARDIAHAKIKERLDAGEEMPQYLKDH 420
Query: 434 PVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKY 493
PVYYAGPAK PE ASGSFGPTTAGRMD +V+ FQA GGS VMLAKGNRSK+VT+AC +
Sbjct: 421 PVYYAGPAKTPEGYASGSFGPTTAGRMDSYVEQFQAAGGSKVMLAKGNRSKQVTDACDAH 480
Query: 494 GGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
GGFYLGSIGGPAA LA D I+KVEV++ EELGMEAVWKIEVE+FPAFIVVDDKGNDFFQ
Sbjct: 481 GGFYLGSIGGPAARLAQDCIKKVEVVEYEELGMEAVWKIEVEDFPAFIVVDDKGNDFFQ 539
>ref|XP_782370.2| PREDICTED: similar to SJCHGC09380 protein [Strongylocentrotus
purpuratus]
ref|XP_001185576.1| PREDICTED: similar to SJCHGC09380 protein [Strongylocentrotus
purpuratus]
Length = 1049
Score = 707 bits (1824), Expect = 0.0, Method: Composition-based stats.
Identities = 331/538 (61%), Positives = 427/538 (79%), Gaps = 4/538 (0%)
Query: 16 PFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHF 75
PF + + H +DT + +T D+VS + +IL+V+ LT+LAS+A+ D+ H
Sbjct: 512 PFIYQDVFEPDHARDTPFKKLTGDFVSTIEVEG--RKILRVKPEALTMLASQAMIDIAHL 569
Query: 76 LRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQV 135
LRP HL LR+I +DPEAS NDRFV+L+L+KNAN+A+A +LPGCQDTGTAI+ G +G+ V
Sbjct: 570 LRPKHLQQLRNILDDPEASSNDRFVSLELLKNANVASAMVLPGCQDTGTAIMMGKRGQNV 629
Query: 136 FTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFF 195
+T+ DEE LSRGV++ YT NLRYSQ PL M+ E NTG NLPAQI+LYA G EY F
Sbjct: 630 WTDERDEEHLSRGVYNTYTQKNLRYSQVSPLDMFKEANTGTNLPAQIELYAVPGNEYHFL 689
Query: 196 FVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMT 255
F+AKGGGSANK FL+Q+TK++LN + L F+ EKI TIGT+ACPPYH++ VVGG SAEMT
Sbjct: 690 FIAKGGGSANKTFLYQQTKALLNKEKLMAFVNEKIKTIGTAACPPYHLSFVVGGLSAEMT 749
Query: 256 MKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARV 315
+K VK AS KY D LPT +E G +RD+E+E+ + ++ + +G+GAQFGGKYF HD RV
Sbjct: 750 LKTVKMASTKYYDTLPTTGNE-HGRAFRDVELEKEIHELSQQLGIGAQFGGKYFCHDVRV 808
Query: 316 IRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPV 375
IR+PRHGASCP+G+GVSCSADRQA+ KI ++G+++E+LE +P KYLPEV E L +
Sbjct: 809 IRLPRHGASCPVGLGVSCSADRQAIGKITEEGVFLEQLETNPIKYLPEVQEGD-LSGEVI 867
Query: 376 KIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPV 435
K++LN PM+ I A L++HP++TR+SLTGT++VARDIAHA+++E L+ + LP Y+K+HPV
Sbjct: 868 KVNLNQPMEDILATLTQHPIRTRISLTGTLVVARDIAHAKLQERLDAGEELPQYMKDHPV 927
Query: 436 YYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGG 495
YYAGPAK PE ASGSFGPTTAGRMD +V+ FQA GGS VMLAKGNRSK VT+ACK +GG
Sbjct: 928 YYAGPAKTPEGYASGSFGPTTAGRMDSYVNSFQAAGGSKVMLAKGNRSKDVTKACKTHGG 987
Query: 496 FYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQ 553
FYLGSIGGPAA+LA D I+KVEVL+ EELGMEA+W+++VE+FPAFIVVDDKGNDFF++
Sbjct: 988 FYLGSIGGPAAILAQDCIKKVEVLEYEELGMEAIWRVDVEDFPAFIVVDDKGNDFFKK 1045
>ref|ZP_02187346.1| Fumarate hydratase class I aerobic [alpha proteobacterium BAL199]
gb|EDP65688.1| Fumarate hydratase class I aerobic [alpha proteobacterium BAL199]
Length = 554
Score = 707 bits (1824), Expect = 0.0, Method: Composition-based stats.
Identities = 342/542 (63%), Positives = 419/542 (77%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
+ P F F + P L TEY +T D+VSV G E++ VE LTLLA +A D+
Sbjct: 18 AMPAFDFTEMFP-LGPDTTEYRKLTSDHVSV--SALGGREVVSVEPEALTLLAEQAFRDI 74
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
H LRP HL LR+I +DP+AS NDRFVA L+KNA+IAA +LP CQDTGTAI+ G KG
Sbjct: 75 SHLLRPGHLQQLRNILDDPDASPNDRFVAYDLLKNASIAAGGVLPMCQDTGTAIVMGKKG 134
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
+ +FT DDEEALSRG+ + Y TNLRYSQ PL M+ EKNT NLPAQ++LYA KG Y
Sbjct: 135 QNIFTGFDDEEALSRGIFNTYVNTNLRYSQLAPLDMFAEKNTASNLPAQVELYADKGDAY 194
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F F+ KGGGSANK FL+Q+TK+VLNP SL FL+EKI T+GTSACPPYH+A+V+GGTSA
Sbjct: 195 KFLFIQKGGGSANKTFLYQQTKAVLNPDSLAKFLDEKIRTLGTSACPPYHLAIVIGGTSA 254
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS +YLD LPT E+ G+ YRDLE EQ ++ + R +G+GAQFGGKYF HD
Sbjct: 255 EFNLKTVKLASTRYLDGLPTAGSET-GHAYRDLEWEQKILQMTREMGIGAQFGGKYFCHD 313
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCPIGIGVSCSADRQA AKI +DG+++E+LE DPA++LP++ E+ L
Sbjct: 314 VRVIRLPRHGASCPIGIGVSCSADRQATAKITRDGVYLERLESDPARFLPDIDENA-LTA 372
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V+IDL PM++IR LS+ P+KTR+SL+G +IVARDIAHA+++E+++ KPLPDY+KN
Sbjct: 373 DAVEIDLTRPMEEIRRTLSQFPIKTRVSLSGPMIVARDIAHAKLQELIDAGKPLPDYVKN 432
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P ASGSFGPTTAGRMD +V F A GGSFV LAKGNRS V EACKK
Sbjct: 433 HPIYYAGPAKTPAGYASGSFGPTTAGRMDSYVGPFMAAGGSFVTLAKGNRSPMVREACKK 492
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGS+GG AA LA++ I+KVEV + ELGMEAVW+IEVE FPAFIVVDDKGNDFF
Sbjct: 493 HGGFYLGSVGGAAAKLALNCIKKVEVQEFPELGMEAVWRIEVEKFPAFIVVDDKGNDFFA 552
Query: 553 QL 554
+
Sbjct: 553 NI 554
>ref|NP_905572.1| fumarate hydratase class I, anaerobic [Porphyromonas gingivalis
W83]
gb|AAQ66471.1| fumarate hydratase class I, anaerobic [Porphyromonas gingivalis
W83]
Length = 548
Score = 706 bits (1822), Expect = 0.0, Method: Composition-based stats.
Identities = 338/543 (62%), Positives = 422/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
+ P FK+ P + TEY L+TK+YVSV G ++LKVE L LLA A D+
Sbjct: 2 ATPEFKYQKPFP-MGDDTTEYYLLTKEYVSVDKFGDH--DVLKVEPEALRLLARTAFHDI 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
+LRP H + I DPEAS+ND+FVAL ++NA ++A LP CQDTGTAII G KG
Sbjct: 59 AFYLRPEHQQQVARILSDPEASENDKFVALTFLRNAEVSAKGQLPFCQDTGTAIILGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
+QV+T G DEE LS GV+ YT NLRYSQN PL MY E NTGCNLPAQIDL A G EY
Sbjct: 119 QQVWTGGHDEEQLSHGVYDTYTQENLRYSQNAPLDMYKEVNTGCNLPAQIDLMAVDGMEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++LNPK+L NFL +K+S++GT+ACPPYH+A V+GGTSA
Sbjct: 179 DFLCIAKGGGSANKTYLYQETKALLNPKTLVNFLVDKMSSLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY D LPT +E G +RD+E+E+ V++ ++G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDNLPTSGNEG-GRAFRDVELEKEVLEAAYHLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
R+IR+PRHGASCP+G+GVSCSADR AKINKDGIW+EK+E +P + +PE + +
Sbjct: 298 VRIIRLPRHGASCPVGMGVSCSADRNIKAKINKDGIWIEKMETNPTRLIPESMREGT-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E ++ + LPDYIKN
Sbjct: 357 TVVKVDLNRPMPEILRELSQYPVSTRLSLSGTIIVGRDIAHAKLKERIDRGEGLPDYIKN 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P+ + SGSFGPTTAGRMD +VDLFQ++GGS VM+AKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPKGMPSGSFGPTTAGRMDSYVDLFQSHGGSMVMIAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
YGGFYLGS+GGPAA+LA DSI+KVE L+ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 477 YGGFYLGSVGGPAAILAQDSIKKVECLEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFT 536
Query: 553 QLR 555
Q+R
Sbjct: 537 QIR 539
>ref|YP_631365.1| fumarate hydratase, class I [Myxococcus xanthus DK 1622]
gb|ABF86094.1| fumarate hydratase, class I [Myxococcus xanthus DK 1622]
Length = 569
Score = 706 bits (1821), Expect = 0.0, Method: Composition-based stats.
Identities = 348/544 (63%), Positives = 422/544 (77%), Gaps = 5/544 (0%)
Query: 11 PKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIG 70
P F+F +LP L +T Y L++KD+VS AG L+V LTLL A+
Sbjct: 22 PTGMTDFQFQDMLP-LGKDETPYRLLSKDHVSTFE--AGGRTFLQVAPEALTLLTREAMR 78
Query: 71 DVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGY 130
D+ H LRP HL L I EDPEAS NDRFVAL+L+KNANIAA +LP CQDTGTAI+ G
Sbjct: 79 DIAHLLRPGHLKQLSHILEDPEASSNDRFVALELLKNANIAAGGVLPSCQDTGTAIVMGK 138
Query: 131 KGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGC 190
KG+ V T G+DEEA+SRGV Y T+NLRYSQ PL MY E NTG NLPAQI+LYAT G
Sbjct: 139 KGQYVITGGNDEEAISRGVFETYQTSNLRYSQMAPLDMYKEVNTGNNLPAQIELYATDGD 198
Query: 191 EYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGT 250
Y+F F+AKGGGSANK++LFQETK++LNP+SL NF++ KI ++GT+ACPPYH+A+V+GGT
Sbjct: 199 AYKFLFMAKGGGSANKSYLFQETKALLNPQSLLNFVDAKIRSLGTAACPPYHLAIVIGGT 258
Query: 251 SAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFA 310
SAE +K KYAS +YLD LPT+ ++ G +RD+ +EQ ++ + + G+GAQFGGKYF
Sbjct: 259 SAEYALKTAKYASARYLDSLPTEGNK-LGRGFRDVALEQEILKLTQRTGIGAQFGGKYFC 317
Query: 311 HDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLL 370
HD RVIR+PRHGASCP+ I VSCSADRQ L KI +DGI++E+LE DPAKYLPE T+ + L
Sbjct: 318 HDVRVIRLPRHGASCPVAIAVSCSADRQILGKITQDGIFLEQLEADPAKYLPETTDGE-L 376
Query: 371 KVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYI 430
VKIDLN PM +IRAELSR+P+KTRLSL+G ++VARDIAHA+++E+L+ +P Y+
Sbjct: 377 GGEVVKIDLNRPMSEIRAELSRYPIKTRLSLSGPLVVARDIAHAKIKEVLDAGNGMPQYL 436
Query: 431 KNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEAC 490
K++ VYYAGPAK PE ASGSFGPTTAGRMD +VD FQA GGSFVMLAKGNRS VTEAC
Sbjct: 437 KDYMVYYAGPAKTPEGYASGSFGPTTAGRMDAYVDQFQAAGGSFVMLAKGNRSPAVTEAC 496
Query: 491 KKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDF 550
KK+GGFYLGSIGGPAA LA D I KVEVL+ ELGMEAVWKIEV +FPAFIVVDDKGNDF
Sbjct: 497 KKHGGFYLGSIGGPAARLAKDCITKVEVLEYAELGMEAVWKIEVVDFPAFIVVDDKGNDF 556
Query: 551 FQQL 554
F +
Sbjct: 557 FANI 560
>ref|YP_001234467.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Acidiphilium cryptum JF-5]
gb|ABQ30548.1| fumarase [Acidiphilium cryptum JF-5]
Length = 548
Score = 705 bits (1820), Expect = 0.0, Method: Composition-based stats.
Identities = 343/547 (62%), Positives = 425/547 (77%), Gaps = 9/547 (1%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
K P F F + P L H DT + + VS + A IL++ L+ LA +A D
Sbjct: 6 KKTPDFAFSTMFP-LGHDDTPWRRLDLGGVSTIE--AAGRTILRIAPETLSALAFQAFHD 62
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
V H LRP HL LR+I +DPEAS+NDR+VA++ +KNANIAA ILP CQDTGTAI+ G K
Sbjct: 63 VSHLLRPGHLRQLRAILDDPEASENDRYVAMEFLKNANIAAGGILPMCQDTGTAIVFGKK 122
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGC- 190
G++V+ GD+EEA S GV+ YT TNLRYSQ PL+MY+E+NTG NLP Q D+ A G
Sbjct: 123 GQRVWVEGDEEEAFSHGVYRTYTETNLRYSQMAPLSMYEERNTGTNLPVQCDIMAAPGEA 182
Query: 191 ---EYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVV 247
E+E FVAKGGGSANK+FL+QET+++LNPK L F+E K+ T+GT+ACPPYH+A+V+
Sbjct: 183 HAEEFELMFVAKGGGSANKSFLYQETRAILNPKKLLEFIETKVKTLGTAACPPYHLAIVI 242
Query: 248 GGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGK 307
GGTSAE TMK VK AS ++LD LPT+ + G+ +RDLE+E+ ++++ R +G+GAQFGGK
Sbjct: 243 GGTSAETTMKTVKLASTRWLDSLPTQGSPT-GHAFRDLELERQILEMTRRLGIGAQFGGK 301
Query: 308 YFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTED 367
YF HD RV+R+PRHGAS P+GIGVSCSADRQ AKI ++G+++E+LE DPAKYLPEVT D
Sbjct: 302 YFCHDVRVVRLPRHGASLPVGIGVSCSADRQIRAKITREGVFLEQLETDPAKYLPEVT-D 360
Query: 368 QLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLP 427
L V+IDLN PM I AELS+HPVKTR++LTG I+VARDIAHA+++E L+ + LP
Sbjct: 361 THLGGDVVQIDLNRPMADILAELSKHPVKTRVALTGPIVVARDIAHAKLKERLDRGEGLP 420
Query: 428 DYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVT 487
DYIKNHPVYYAGPAK PE +A+GSFGPTTAGRMD +V+ FQA GGS VMLAKGNRS+ V
Sbjct: 421 DYIKNHPVYYAGPAKTPEGMATGSFGPTTAGRMDSYVEEFQAAGGSLVMLAKGNRSRAVR 480
Query: 488 EACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKG 547
+ACK +GGFYLGSIGGPAA+LA D+IRKVEVL+ ELGMEAVW+IEVENFPAFIVVDDKG
Sbjct: 481 DACKAHGGFYLGSIGGPAAVLARDNIRKVEVLEYPELGMEAVWRIEVENFPAFIVVDDKG 540
Query: 548 NDFFQQL 554
NDFF L
Sbjct: 541 NDFFADL 547
>ref|YP_001929009.1| fumarate hydratase class I anaerobic [Porphyromonas gingivalis ATCC
33277]
dbj|BAG33412.1| fumarate hydratase class I anaerobic [Porphyromonas gingivalis ATCC
33277]
Length = 548
Score = 705 bits (1819), Expect = 0.0, Method: Composition-based stats.
Identities = 337/543 (62%), Positives = 421/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
+ P FK+ P + TEY L+TK+YVSV G ++LKVE L LLA A D+
Sbjct: 2 ATPEFKYQKPFP-MGDDTTEYYLLTKEYVSVDKFGDH--DVLKVEPEALRLLARTAFHDI 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
+LRP H + I DPEAS+ND+FVAL ++NA ++A LP CQDTGTAII G KG
Sbjct: 59 AFYLRPEHQQQVARILSDPEASENDKFVALTFLRNAEVSAKGQLPFCQDTGTAIILGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
+QV+T G DEE LS GV+ YT NLRYSQN PL MY E NTGCNLPAQIDL A G EY
Sbjct: 119 QQVWTGGHDEEQLSHGVYDTYTQENLRYSQNAPLDMYKEVNTGCNLPAQIDLMAVDGMEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++LNPK+L NFL +K+S++GT+ACPPYH+A V+GGTSA
Sbjct: 179 DFLCIAKGGGSANKTYLYQETKALLNPKTLVNFLVDKMSSLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY D LPT +E G +RD+E+E+ V++ +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDNLPTSGNEG-GRAFRDVELEKEVLEAAYRLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
R+IR+PRHGASCP+G+GVSCSADR AKINKDGIW+EK+E +P + +PE + +
Sbjct: 298 VRIIRLPRHGASCPVGMGVSCSADRNIKAKINKDGIWIEKMETNPTRLIPESMREGT-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E ++ + LPDY+KN
Sbjct: 357 TVVKVDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERIDRGEGLPDYVKN 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P+ + SGSFGPTTAGRMD +VDLFQ++GGS VM+AKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPKGMPSGSFGPTTAGRMDSYVDLFQSHGGSMVMIAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
YGGFYLGS+GGPAA+LA DSI+KVE L+ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 477 YGGFYLGSVGGPAAILAQDSIKKVECLEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFT 536
Query: 553 QLR 555
Q+R
Sbjct: 537 QIR 539
>gb|AAW26769.1| SJCHGC09380 protein [Schistosoma japonicum]
Length = 565
Score = 705 bits (1819), Expect = 0.0, Method: Composition-based stats.
Identities = 333/555 (60%), Positives = 437/555 (78%), Gaps = 9/555 (1%)
Query: 1 MLRRSSLWFAPKSAPPFKFVPLLP--HLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEA 58
+LRR+ ++ PF + +L + +T + +T D+VS+ EILK+++
Sbjct: 14 LLRRN---LGSQAVKPFFYQDILQLDKPPYAETPFRKLTGDFVSLKKIDD--KEILKIDS 68
Query: 59 AGLTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPG 118
L LL+ +A+ DV H LRP+HL SL +I DPEAS+ND+FVAL+L+KNAN+AA +LPG
Sbjct: 69 KALILLSQQAMIDVAHLLRPAHLQSLSNILRDPEASNNDKFVALELLKNANVAAGMVLPG 128
Query: 119 CQDTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNL 178
CQDTGTAI KG+ V+T+G+D EA+S+G+++ YT++ LRYSQ L M+ EKNTG NL
Sbjct: 129 CQDTGTAICMAKKGQFVWTDGNDAEAISQGIYNTYTSSYLRYSQVAALDMFTEKNTGTNL 188
Query: 179 PAQIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSAC 238
PAQI++Y+T G EY F F+AKGGGSANK FL+Q+TK++LNP SL +F+ EKI T+GT+AC
Sbjct: 189 PAQIEIYSTGGNEYSFLFIAKGGGSANKTFLYQQTKALLNPTSLYSFVNEKIKTLGTAAC 248
Query: 239 PPYHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNI 298
PPYH+AVVVGGTSAE T+K VK ASCKYLD LP+ +E G +RD E E+ ++ + + +
Sbjct: 249 PPYHLAVVVGGTSAEFTLKTVKLASCKYLDHLPSTGNE-HGRAFRDREAEEKILHLTQKV 307
Query: 299 GMGAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPA 358
G+GAQFGGKYF HD RVIR+PRHGASCP+GIGVSCSADRQ L +I DG+++E+LE DP+
Sbjct: 308 GIGAQFGGKYFCHDVRVIRLPRHGASCPVGIGVSCSADRQILGRITNDGVFLEQLETDPS 367
Query: 359 KYLPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMRE 418
+YLP+ + +Q L VK++LN+PM +I AELS++P+KTRLSLTGT++VARDIAHA+++E
Sbjct: 368 QYLPDPSLNQ-LPTDVVKVNLNLPMKEILAELSKYPIKTRLSLTGTLVVARDIAHAKIKE 426
Query: 419 MLENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLA 478
L++ +P+PDY NHPVYYAGPAK P ASGSFGPTTAGRMD +V FQ GGS +MLA
Sbjct: 427 RLDSGQPMPDYFCNHPVYYAGPAKTPMNYASGSFGPTTAGRMDSYVGQFQQAGGSLIMLA 486
Query: 479 KGNRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFP 538
KGNRSK VT AC+K+GGFYLGSIGGPAA+LA + I+KVEVL+ ELGMEA+W++EVE+FP
Sbjct: 487 KGNRSKAVTNACRKHGGFYLGSIGGPAAILAQNCIKKVEVLEYPELGMEAIWRVEVEDFP 546
Query: 539 AFIVVDDKGNDFFQQ 553
AFIVVDDKGNDFF++
Sbjct: 547 AFIVVDDKGNDFFKE 561
>ref|ZP_03878233.1| fumarase [Haliangium ochraceum DSM 14365]
gb|EEJ01852.1| fumarase [Haliangium ochraceum DSM 14365]
Length = 548
Score = 702 bits (1812), Expect = 0.0, Method: Composition-based stats.
Identities = 342/538 (63%), Positives = 423/538 (78%), Gaps = 5/538 (0%)
Query: 17 FKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F++ +LP L DT+Y L+TKD +S AG ++VE LT LA A+ D+ H L
Sbjct: 4 FQYQDMLP-LGADDTDYRLITKDGISTFE--AGGQTFVRVEPEVLTQLAREAMRDIAHLL 60
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
RPSHL+ LR I +DPEASDNDRFVAL L+KNANIAA +LP CQDTGTAII G KG+ +F
Sbjct: 61 RPSHLSQLRRILDDPEASDNDRFVALDLLKNANIAAGGVLPMCQDTGTAIIKGKKGQNIF 120
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFF 196
T G DE AL+RGV+ Y + NLRYSQ PLTMY EKNT NLPAQI++ A G Y+F F
Sbjct: 121 TGGGDEVALARGVYDTYQSGNLRYSQLAPLTMYTEKNTKNNLPAQIEIAAIDGSAYKFLF 180
Query: 197 VAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTM 256
+AKGGGSANK++L+QETK++LNP+SL F++ KI ++GT+ACPPYH+AVVVGGTSAE ++
Sbjct: 181 MAKGGGSANKSYLYQETKALLNPESLLAFVDAKIRSLGTAACPPYHLAVVVGGTSAEYSL 240
Query: 257 KAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVI 316
K AS +YLD LP + +E G+ +RD E+E+ + + R G+GAQFGGKYF HD RVI
Sbjct: 241 AVAKLASARYLDSLPPQGNE-LGHGFRDRELEEQIHGLTRKSGIGAQFGGKYFCHDVRVI 299
Query: 317 RMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVK 376
R+PRHGASCP+ + VSCSADRQALAKI +G+++E LE DPAKYLPE T + L V+
Sbjct: 300 RLPRHGASCPVAVAVSCSADRQALAKITAEGVFLEALERDPAKYLPETTASE-LDGDVVR 358
Query: 377 IDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVY 436
+DLN PM+ IRA LSR+P+KTRLSLTGT++VARDIAHA+++E L+ + +P+Y+++HPVY
Sbjct: 359 VDLNQPMNDIRALLSRYPIKTRLSLTGTVVVARDIAHAKLKERLDAGEGMPEYLRDHPVY 418
Query: 437 YAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGF 496
YAGPAK PE ASGSFGPTTA RMDP+VDLFQ +GGS VMLAKGNRS+ VTEAC K+GGF
Sbjct: 419 YAGPAKTPEGYASGSFGPTTASRMDPYVDLFQEHGGSMVMLAKGNRSRAVTEACHKHGGF 478
Query: 497 YLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQL 554
YLGSIGGPAA LA D I+KVEVL+ ELGMEAVW+IEVE+FPAFIVVDDKGNDFF +
Sbjct: 479 YLGSIGGPAARLAKDCIKKVEVLEYPELGMEAVWRIEVEDFPAFIVVDDKGNDFFADI 536
>ref|XP_001417167.1| predicted protein [Ostreococcus lucimarinus CCE9901]
gb|ABO95460.1| predicted protein [Ostreococcus lucimarinus CCE9901]
Length = 560
Score = 702 bits (1812), Expect = 0.0, Method: Composition-based stats.
Identities = 341/523 (65%), Positives = 410/523 (78%), Gaps = 3/523 (0%)
Query: 29 KDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFLRPSHLASLRSIF 88
K+ E+ LVT+D V+ GA +KV LT LA+RA+ DV H LRP HL LR I
Sbjct: 36 KEVEWRLVTRDGVTTT-AGADGETYVKVAPEALTALAARAVRDVSHLLRPGHLKQLRGIL 94
Query: 89 EDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVFTNGDDEEALSRG 148
+DPEAS NDRFVAL+L+KNA +AA +LPGCQDTGTAI+ G +G +V T+G+DE ALSRG
Sbjct: 95 DDPEASKNDRFVALELLKNACVAAGMVLPGCQDTGTAIVMGKRGGRVLTDGEDERALSRG 154
Query: 149 VHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFFVAKGGGSANKAF 208
V+ Y TTNLRYSQ PLTM++EKNTG NLPAQIDLYATKG EY F F+ KGGGSANK F
Sbjct: 155 VYDTYKTTNLRYSQVAPLTMFEEKNTGSNLPAQIDLYATKGDEYHFQFMTKGGGSANKTF 214
Query: 209 LFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTMKAVKYASCKYLD 268
LFQ+TK+VLN SL +FLEEKI IGTSACPPYH+A+V+GG SAE +K VK AS +Y D
Sbjct: 215 LFQQTKAVLNEASLLSFLEEKIKNIGTSACPPYHLAIVIGGLSAEQNLKTVKMASARYYD 274
Query: 269 ELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVIRMPRHGASCPIG 328
L T +E G +RDLE E+ + + + +G+GAQFGGKYF HD RVIR+PRHGASCPIG
Sbjct: 275 NLHTSGNEL-GRAFRDLEWEEKIHKLTQTMGIGAQFGGKYFCHDVRVIRLPRHGASCPIG 333
Query: 329 IGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVKIDLNMPMDKIRA 388
+GVSCSADRQAL KI KDG+++E LE DP+KYLP+V ED L V +DLN PM +I A
Sbjct: 334 LGVSCSADRQALGKITKDGVFIEALETDPSKYLPDVREDNLSN-EVVHVDLNRPMSEILA 392
Query: 389 ELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVYYAGPAKRPEALA 448
LS V TRL+LTG ++VARDIAHA+++E L+ + LP Y+K+H VYYAGPAK PE +A
Sbjct: 393 TLSACEVTTRLTLTGPLVVARDIAHAKLKEQLDRGEDLPQYMKDHAVYYAGPAKTPEGMA 452
Query: 449 SGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGFYLGSIGGPAALL 508
SGSFGPTTAGRMD +VD FQA GGS VMLAKGNRS VT ACK +GGFYLGSIGGPAA+L
Sbjct: 453 SGSFGPTTAGRMDSYVDQFQAAGGSMVMLAKGNRSAAVTRACKTHGGFYLGSIGGPAAIL 512
Query: 509 AMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
A ++I+KV+VL+ ELGMEAVWKI+VENFPAF+VVDDKG++FF
Sbjct: 513 AQNNIKKVDVLEFPELGMEAVWKIQVENFPAFVVVDDKGHNFF 555
>ref|ZP_02858786.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Rhizobium leguminosarum bv. trifolii WSM2304]
gb|EDS66893.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Rhizobium leguminosarum bv. trifolii WSM2304]
Length = 535
Score = 702 bits (1812), Expect = 0.0, Method: Composition-based stats.
Identities = 346/524 (66%), Positives = 409/524 (78%), Gaps = 4/524 (0%)
Query: 31 TEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFLRPSHLASLRSIFED 90
T Y ++ DYVSV + EIL VE G+ LLA A D+ H LRP HL L SI +D
Sbjct: 13 TPYRKISGDYVSVDSFKG--QEILTVEPEGIRLLAETAFADINHLLRPGHLKQLASILDD 70
Query: 91 PEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVFTNGDDEEALSRGVH 150
PEA+DNDRFVA L+KNANIAA +LP CQDTGTAII G KG +V+T G D AL+RGV
Sbjct: 71 PEATDNDRFVAYDLLKNANIAAGGVLPMCQDTGTAIIMGKKGRRVWTEGGDTAALARGVM 130
Query: 151 HIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFFVAKGGGSANKAFLF 210
Y NLRYSQ P+ M++EKNT NLPAQID+Y YEF FVAKGGGSANK FL+
Sbjct: 131 DAYEKKNLRYSQLAPVKMFEEKNTRNNLPAQIDIYEEGTDAYEFLFVAKGGGSANKTFLY 190
Query: 211 QETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTMKAVKYASCKYLDEL 270
Q T S+L + +FL+EKI T+GT+ACPPYH+A+V+GGTSAEM +K VK AS +YLDEL
Sbjct: 191 QGTPSLLTHDRMIDFLKEKILTLGTAACPPYHLAIVIGGTSAEMNLKTVKLASTRYLDEL 250
Query: 271 PTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVIRMPRHGASCPIGIG 330
PT+ ES G+ +RDLEME+ + + + +G+GAQFGGKYF HD RVIR+PRHGAS PIG+G
Sbjct: 251 PTEGSES-GHAFRDLEMEKEIHRLTQQMGVGAQFGGKYFCHDVRVIRLPRHGASLPIGLG 309
Query: 331 VSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVKIDLNMPMDKIRAEL 390
VSCSADRQA KI +DGI++E+LE DP+KY+PE+ E +L + V IDLN PM + AEL
Sbjct: 310 VSCSADRQAKGKITRDGIFIEQLESDPSKYMPEIDEAKLSE-STVHIDLNRPMADVLAEL 368
Query: 391 SRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVYYAGPAKRPEALASG 450
SRHPVKTRLSLTGTIIVARD+AHA++RE LEN + +P+Y+KNHPVYYAGPAK P ASG
Sbjct: 369 SRHPVKTRLSLTGTIIVARDLAHAKIRERLENGEGMPEYLKNHPVYYAGPAKTPAGYASG 428
Query: 451 SFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGFYLGSIGGPAALLAM 510
SFGPTTAGRMD +VD FQ+ GGS VMLAKGNRS+ V EACKK+GGFYLGSIGGPAA LA
Sbjct: 429 SFGPTTAGRMDSYVDQFQSFGGSMVMLAKGNRSRAVREACKKHGGFYLGSIGGPAARLAQ 488
Query: 511 DSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQL 554
D IRKVEV + ELGMEAVWKIEVENFPAFIV+DDKGNDFFQ+L
Sbjct: 489 DCIRKVEVFEYPELGMEAVWKIEVENFPAFIVIDDKGNDFFQEL 532
>ref|XP_847862.1| fumarate hydratase, putative [Leishmania major strain Friedlin]
gb|AAZ09654.1| fumarate hydratase, putative [Leishmania major strain Friedlin]
Length = 568
Score = 700 bits (1807), Expect = 0.0, Method: Composition-based stats.
Identities = 336/537 (62%), Positives = 417/537 (77%), Gaps = 8/537 (1%)
Query: 19 FVPLLPHLHHKDTEYTLV--TKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F P PH H TE+ V ++ YV V + LKV LT+LA RA DV HF
Sbjct: 35 FQPTDPH--HHQTEFAKVEGSEKYVEEVEVFG--RQALKVNPEALTILAHRAFSDVHHFF 90
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
R HL R EDPEASDNDR+VA L+KNA IAA R+LP CQDTGTAI+ G +GE +
Sbjct: 91 RKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCW 150
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFF 196
T G+DE+ LS+G+ + Y NLRYSQ L M+ E NTG NLPAQ+DL A G +YEF F
Sbjct: 151 TGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLF 210
Query: 197 VAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTM 256
+AKGGGSANKA+L+QETK++LNPKSLR F+EEK+ T+GT+ACPPYH+A+V+GGTSAEMTM
Sbjct: 211 IAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTM 270
Query: 257 KAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVI 316
K VK ASC+Y D LPT D+ G +RD E E++VM++ + G+GAQFGGKYFAH ARVI
Sbjct: 271 KTVKLASCRYYDSLPTTGDKY-GRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVI 329
Query: 317 RMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVK 376
R+PRHGASCP+G+ VSCSADRQ LA INK GI++E+LE +PA+YLP++ E L VK
Sbjct: 330 RLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDIPEVH-LSTTSVK 388
Query: 377 IDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVY 436
+DL P+DK+R +LS++PV TR+ L GT+IVARDIAHA+++EM++N +PLP+Y+K P+Y
Sbjct: 389 VDLKRPIDKVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIY 448
Query: 437 YAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGF 496
YAGPAK PE ASGSFGPTTAGRMD +VDLFQ++GGS++ LAKGNRSK+VT+ACKK+GGF
Sbjct: 449 YAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGF 508
Query: 497 YLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQ 553
YLGSIGGPAA+LA DSI++V L ELGMEAVWKIEVE+FPAFIVVDDKGND + +
Sbjct: 509 YLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSK 565
>ref|NP_824394.1| fumarate hydratase class I [Streptomyces avermitilis MA-4680]
dbj|BAC70929.1| putative fumarate hydratase class I [Streptomyces avermitilis
MA-4680]
Length = 558
Score = 699 bits (1805), Expect = 0.0, Method: Composition-based stats.
Identities = 343/539 (63%), Positives = 422/539 (78%), Gaps = 5/539 (0%)
Query: 15 PPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQH 74
P F + LLP T Y LVT + VS A LKVE L LA AI D+QH
Sbjct: 5 PEFAYTDLLPQ-GEDTTPYRLVTSEGVSTFE--ADGRTFLKVEPEALRKLAEEAIHDIQH 61
Query: 75 FLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQ 134
+LRP+HLA LR I +DPEAS ND+FVAL L+KNANIAAA +LP CQDTGTAI+ G +G+
Sbjct: 62 YLRPAHLAQLRRIIDDPEASGNDKFVALDLLKNANIAAAGVLPMCQDTGTAIVMGKRGQN 121
Query: 135 VFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEF 194
V T G DE ALSRG++ Y NLRYSQ PLTM++EKNTG NLPAQI+LYAT G Y+F
Sbjct: 122 VLTEGGDESALSRGIYDAYKNLNLRYSQMAPLTMWEEKNTGSNLPAQIELYATDGGAYKF 181
Query: 195 FFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEM 254
F+AKGGGSANK+FL+QETK+VLN S+ FLEEKI ++GT+ACPPYH+A+VVGGTSAE
Sbjct: 182 LFMAKGGGSANKSFLYQETKAVLNEGSMMKFLEEKIRSLGTAACPPYHLAIVVGGTSAEY 241
Query: 255 TMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDAR 314
+K KYAS YLDE+P + E G+ +RD ++E+ V ++ + IG+GAQFGGKYF HD R
Sbjct: 242 ALKTAKYASAHYLDEIPAEGSE-LGHGFRDKDLEEKVFELTQKIGIGAQFGGKYFCHDVR 300
Query: 315 VIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPP 374
V+R+PRHGASCP+ I VSCSADRQA+AKI +G+++E+LE DPA++LPE T+D L +
Sbjct: 301 VVRLPRHGASCPVAIAVSCSADRQAVAKITAEGVFLEQLETDPARFLPETTDDHLDESGD 360
Query: 375 -VKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNH 433
V+IDLN PMD I AEL+++PVKTRLSL+G ++VARDIAHA+++E L+ + +P Y+K+H
Sbjct: 361 VVRIDLNQPMDDILAELTKYPVKTRLSLSGPLVVARDIAHAKIKERLDAGEEMPQYLKDH 420
Query: 434 PVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKY 493
PVYYAGPAK PE ASGSFGPTTAGRMD +V+ FQA GGS VMLAKGNRS +VT AC+ +
Sbjct: 421 PVYYAGPAKTPEGYASGSFGPTTAGRMDSYVEQFQAAGGSKVMLAKGNRSAQVTNACEAH 480
Query: 494 GGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
GGFYLGSIGGPAA LA D I+KVEV++ EELGMEAVWKIEVE+FPAF+VVDDKGNDFF+
Sbjct: 481 GGFYLGSIGGPAARLAQDCIKKVEVVEYEELGMEAVWKIEVEDFPAFVVVDDKGNDFFK 539
>ref|XP_001745789.1| predicted protein [Monosiga brevicollis MX1]
gb|EDQ89213.1| predicted protein [Monosiga brevicollis MX1]
Length = 574
Score = 699 bits (1805), Expect = 0.0, Method: Composition-based stats.
Identities = 331/503 (65%), Positives = 403/503 (80%), Gaps = 2/503 (0%)
Query: 52 EILKVEAAGLTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIA 111
E+L+V LTLL+ +A+ D+ H LRP HL LR I +DPE+S NDRFVAL+L+KNA IA
Sbjct: 70 EVLRVAPEALTLLSEQAMIDIAHLLRPGHLQQLRKILDDPESSKNDRFVALELLKNAQIA 129
Query: 112 AARILPGCQDTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDE 171
A +LPGCQDTGTAI G KG+ V++ GDD EALSRGV + YT NLRYSQ PL M+ E
Sbjct: 130 AGMVLPGCQDTGTAICIGKKGQHVWSTGDDGEALSRGVFNAYTRRNLRYSQVAPLDMFQE 189
Query: 172 KNTGCNLPAQIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKIS 231
KNTG NLPAQI+LY+T G EY F F+AKGGGSANK FLFQ+TK+VLN K L FLEEKI
Sbjct: 190 KNTGSNLPAQIELYSTPGNEYHFQFMAKGGGSANKTFLFQQTKAVLNEKKLEQFLEEKIK 249
Query: 232 TIGTSACPPYHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMV 291
T+GT+ACPPYH+A+V+GG SAEM +K VK AS +Y D L T +E G +RDLE E+ +
Sbjct: 250 TLGTAACPPYHLAIVIGGLSAEMNLKTVKMASTRYYDNLHTSGNE-MGRAFRDLEWEERI 308
Query: 292 MDICRNIGMGAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVE 351
+ +N+G+GAQFGGKYF HD RVIR+PRHGASCPIGIGVSCSADRQAL KI K+G+++E
Sbjct: 309 HKLTQNLGIGAQFGGKYFCHDVRVIRLPRHGASCPIGIGVSCSADRQALGKITKEGVFIE 368
Query: 352 KLEMDPAKYLPEVTEDQL-LKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARD 410
LE +P +YLPEVTE L K VKI+LN PM+ IR +LS +P++TRLSLTG +IVARD
Sbjct: 369 ALETNPGQYLPEVTESDLGDKAEVVKINLNQPMEDIRKQLSSYPIRTRLSLTGKLIVARD 428
Query: 411 IAHARMREMLENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQAN 470
IAHA+++E +++ + LPDYIKNH +YYAGPAK PE ASGSFGPTTAGRMD +V F N
Sbjct: 429 IAHAKLQERIDSGEGLPDYIKNHIIYYAGPAKTPEGYASGSFGPTTAGRMDSYVGPFMEN 488
Query: 471 GGSFVMLAKGNRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVW 530
GGSF+ LAKGNRSK+VT ACK GGFYLGSIGGPAA+LA++SI+ V+V + ELGMEA+W
Sbjct: 489 GGSFITLAKGNRSKQVTNACKANGGFYLGSIGGPAAILALNSIKNVQVKEYPELGMEAIW 548
Query: 531 KIEVENFPAFIVVDDKGNDFFQQ 553
+I+VE+FPAFIVVDDKGNDFFQ+
Sbjct: 549 EIDVEDFPAFIVVDDKGNDFFQE 571
>ref|YP_768288.1| utative fumarate hydratase class I, aerobic [Rhizobium
leguminosarum bv. viciae 3841]
emb|CAK08192.1| utative fumarate hydratase class I, aerobic [Rhizobium
leguminosarum bv. viciae 3841]
Length = 535
Score = 699 bits (1803), Expect = 0.0, Method: Composition-based stats.
Identities = 343/524 (65%), Positives = 411/524 (78%), Gaps = 4/524 (0%)
Query: 31 TEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFLRPSHLASLRSIFED 90
T Y ++ D+VSV EIL VE G+ LLA A D+ H LRP HL L SI +D
Sbjct: 13 TPYRKISGDHVSVDTFKG--QEILTVEPEGIRLLAETAFADINHLLRPGHLKQLASILDD 70
Query: 91 PEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVFTNGDDEEALSRGVH 150
PEA+DNDRFVA L+KNANIAA +LP CQDTGTAII G KG +V+T+G+D AL+RGV
Sbjct: 71 PEATDNDRFVAYDLLKNANIAAGGVLPMCQDTGTAIIMGKKGRRVWTDGEDTAALARGVM 130
Query: 151 HIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFFVAKGGGSANKAFLF 210
Y NLRYSQ P+ M++EKNT NLPAQID+Y YEF FVAKGGGSANK FL+
Sbjct: 131 DAYEKKNLRYSQLAPVKMFEEKNTRNNLPAQIDIYEEGTDAYEFLFVAKGGGSANKTFLY 190
Query: 211 QETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTMKAVKYASCKYLDEL 270
Q T S+L + +FL+EKI T+GT+ACPPYH+A+V+GGTSAEM +K VK AS +YLDEL
Sbjct: 191 QGTPSLLTHDRMIDFLKEKILTLGTAACPPYHLAIVIGGTSAEMNLKTVKLASTRYLDEL 250
Query: 271 PTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVIRMPRHGASCPIGIG 330
PT+ ES G+ +RD+EME+ + + + +G+GAQFGGKYF HD RVIR+PRHGAS PIG+G
Sbjct: 251 PTEGSES-GHAFRDVEMEKEIHKLTQQMGVGAQFGGKYFCHDVRVIRLPRHGASLPIGLG 309
Query: 331 VSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVKIDLNMPMDKIRAEL 390
VSCSADRQA +I +DGI+VE+LE DP+KY+PE+ E +L + V+IDLN PM ++ AEL
Sbjct: 310 VSCSADRQAKGRITRDGIFVEQLETDPSKYMPEIDEAKLSE-STVRIDLNRPMAEVLAEL 368
Query: 391 SRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVYYAGPAKRPEALASG 450
SRHPVKTRLSLTGTIIVARD+AHA++RE LE + +PDY+KNHPVYYAGPAK P ASG
Sbjct: 369 SRHPVKTRLSLTGTIIVARDLAHAKIRERLEKGEGMPDYLKNHPVYYAGPAKTPVGYASG 428
Query: 451 SFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGFYLGSIGGPAALLAM 510
SFGPTTAGRMD +VD FQ+ GGS VMLAKGNRS+ V EACKK+GGFYLGSIGGPAA LA
Sbjct: 429 SFGPTTAGRMDSYVDQFQSFGGSMVMLAKGNRSRPVREACKKHGGFYLGSIGGPAARLAQ 488
Query: 511 DSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQL 554
D IRKVEV + ELGMEAVWKIEVE+FPAFIV+DDKGNDFFQ+L
Sbjct: 489 DCIRKVEVFEYPELGMEAVWKIEVEDFPAFIVIDDKGNDFFQEL 532
>ref|ZP_03815532.1| fumarase [Actinosynnema mirum DSM 43827]
gb|EEH78609.1| fumarase [Actinosynnema mirum DSM 43827]
Length = 554
Score = 698 bits (1802), Expect = 0.0, Method: Composition-based stats.
Identities = 343/545 (62%), Positives = 419/545 (76%), Gaps = 6/545 (1%)
Query: 11 PKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIG 70
P F++ +LP TEY LVT++ VSVV A + L+VE LTLLA AI
Sbjct: 2 PAVPTTFQYTDVLPLAADTTTEYRLVTQEGVSVVE--AAGRKFLQVEPETLTLLAKEAIR 59
Query: 71 DVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGY 130
D+QH LRPSHLA LR+I +DPEAS NDRFVA L++NA I+A +LP CQDTGTAI+ G
Sbjct: 60 DIQHLLRPSHLAQLRAIVDDPEASGNDRFVATDLLRNACISAGGVLPMCQDTGTAIVMGK 119
Query: 131 KGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGC 190
+ E V T G DEEALSRG+ Y NLRYSQ P+T +DEKNTG NLPAQ+DL+ G
Sbjct: 120 RTESVLTGGADEEALSRGIFEAYQELNLRYSQMAPVTFWDEKNTGTNLPAQLDLFTAPGV 179
Query: 191 E--YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVG 248
E YEF F+AKGGGSANK FL+QETK++LNP L FL+EK+ ++GT+ACPPYH+AVVVG
Sbjct: 180 EPKYEFLFMAKGGGSANKTFLYQETKALLNPARLARFLDEKLRSLGTAACPPYHLAVVVG 239
Query: 249 GTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKY 308
G SAE +K K AS +YLD LPT+ + G+ +RD+E+EQ V+++ R+ G+GAQFGGKY
Sbjct: 240 GLSAEQNLKVAKLASARYLDNLPTE-GSAAGHAFRDVELEQQVLELTRDFGIGAQFGGKY 298
Query: 309 FAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQ 368
F HD RVIR+PRHGASCP+G+ VSCSADRQA AKI +G+++E+LE DPAKYLPEVT D+
Sbjct: 299 FCHDVRVIRLPRHGASCPVGVAVSCSADRQAKAKITPEGVFIEQLERDPAKYLPEVT-DE 357
Query: 369 LLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPD 428
L V+IDL PM +IR LS PVKTR+SLTG ++VARDIAHA+++E L+ + +P
Sbjct: 358 ALSDEVVQIDLTRPMAEIREALSALPVKTRVSLTGPLVVARDIAHAKIKERLDAGEGMPQ 417
Query: 429 YIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTE 488
Y+++HPVYYAGPAK PE ASGSFGPTTAGRMD +V+ FQA GGS VMLAKGNRSK+VT
Sbjct: 418 YLRDHPVYYAGPAKTPEGYASGSFGPTTAGRMDSYVEQFQAEGGSLVMLAKGNRSKQVTS 477
Query: 489 ACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGN 548
AC +GGFYLGSIGGPAA LA D IRKVEVL+ ELGMEAVW+IEVE+FPAF+VVDDKGN
Sbjct: 478 ACATHGGFYLGSIGGPAARLAQDCIRKVEVLEYAELGMEAVWRIEVEDFPAFVVVDDKGN 537
Query: 549 DFFQQ 553
DFF +
Sbjct: 538 DFFAE 542
>ref|XP_814517.1| fumarate hydratase, putative [Trypanosoma cruzi strain CL Brener]
gb|EAN92666.1| fumarate hydratase, putative [Trypanosoma cruzi]
Length = 565
Score = 698 bits (1801), Expect = 0.0, Method: Composition-based stats.
Identities = 340/547 (62%), Positives = 414/547 (75%), Gaps = 6/547 (1%)
Query: 10 APKSAPPFKFVPLL--PHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASR 67
A SA F + P+ HH +TEY ++ DYV V IL+V+ LT LA +
Sbjct: 22 AKASASEFHYEPIFQPSDPHHDETEYYMLEGDYVKTVEVLG--KTILQVKPEALTALAHQ 79
Query: 68 AIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAII 127
A DV HF R HL+ R I EDPEAS+NDRFVA L++NA +AA R+LP CQDTGTAI+
Sbjct: 80 AFADVHHFFRKDHLSGWRRILEDPEASNNDRFVAHTLLQNACVAAGRVLPACQDTGTAIV 139
Query: 128 AGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYAT 187
G +GE +T G+DE+ LS+G+ Y LRYSQ L M+ E NTG NLPAQ DL AT
Sbjct: 140 LGKRGELCWTGGEDEKHLSKGIWDCYMNRYLRYSQTAALDMFKEVNTGNNLPAQFDLLAT 199
Query: 188 KGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVV 247
G EY F F+AKGGGSANKAFL+QETK++LNPKSLR F+E+K+ T+GT+ACPPYH+A+V+
Sbjct: 200 AGNEYHFLFIAKGGGSANKAFLYQETKALLNPKSLREFIEQKLKTLGTAACPPYHIALVI 259
Query: 248 GGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGK 307
GGTSAEMTMK VK ASC+Y D LP +++ G +RDLE E +VMDI G+GAQFGGK
Sbjct: 260 GGTSAEMTMKTVKLASCRYYDSLPITGNKN-GRAFRDLEWEAIVMDIACKSGIGAQFGGK 318
Query: 308 YFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTED 367
YFAH ARVIR+PRHGASCP+G+GVSCSADRQ LAKI G++VE+L DPA+YLP++
Sbjct: 319 YFAHQARVIRLPRHGASCPVGLGVSCSADRQILAKITPKGVFVERLVRDPAQYLPDLPPS 378
Query: 368 QLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLP 427
L V +DLN PM +IR LS++PV TRLSLTGT+IVARDIAHA++ E L NN+ LP
Sbjct: 379 S-LSTNVVNVDLNQPMSEIRKLLSQYPVTTRLSLTGTLIVARDIAHAKIMERLNNNEELP 437
Query: 428 DYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVT 487
Y+K+HPVYYAGPAK P+ +ASGSFGPTTAGRMD ++ F A GGSFV LAKGNRSK VT
Sbjct: 438 QYMKDHPVYYAGPAKTPKGMASGSFGPTTAGRMDSYICPFMAAGGSFVTLAKGNRSKAVT 497
Query: 488 EACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKG 547
EACKKYGGFYLGSIGG AA+LA ++I+ VEV++ ELGMEAVW+I+V +FPAFIVVDDKG
Sbjct: 498 EACKKYGGFYLGSIGGSAAILAQNNIKNVEVVEFPELGMEAVWRIDVVDFPAFIVVDDKG 557
Query: 548 NDFFQQL 554
NDFF +L
Sbjct: 558 NDFFSKL 564
>ref|XP_001466723.1| fumarate hydratase [Leishmania infantum]
gb|ABF20374.1| fumarate hydratase [Leishmania infantum]
gb|ABF20375.1| fumarate hydratase [Leishmania infantum]
gb|ABF20377.1| fumarate hydratase [Leishmania infantum]
gb|ABF20378.1| fumarate hydratase [Leishmania infantum]
gb|ABF20379.1| fumarate hydratase [Leishmania infantum]
gb|ABF20380.1| fumarate hydratase [Leishmania infantum]
gb|ABF20381.1| fumarate hydratase [Leishmania infantum]
gb|ABF20382.1| fumarate hydratase [Leishmania donovani]
gb|ABF20383.1| fumarate hydratase [Leishmania donovani]
gb|ABF20384.1| fumarate hydratase [Leishmania donovani archibaldi]
gb|ABF20385.1| fumarate hydratase [Leishmania donovani]
gb|ABF20386.1| fumarate hydratase [Leishmania donovani]
gb|ABF20387.1| fumarate hydratase [Leishmania infantum]
gb|ABF20389.1| fumarate hydratase [Leishmania donovani]
gb|ABF20390.1| fumarate hydratase [Leishmania donovani]
gb|ABF20391.1| fumarate hydratase [Leishmania infantum]
gb|ABF20392.1| fumarate hydratase [Leishmania infantum]
gb|ABF20393.1| fumarate hydratase [Leishmania infantum]
gb|ABF20394.1| fumarate hydratase [Leishmania infantum]
gb|ABF20396.1| fumarate hydratase [Leishmania infantum]
gb|ABF20397.1| fumarate hydratase [Leishmania donovani archibaldi]
gb|ABF20399.1| fumarate hydratase [Leishmania donovani]
gb|ABF20400.1| fumarate hydratase [Leishmania infantum]
emb|CAM69767.1| fumarate hydratase, putative [Leishmania infantum]
Length = 568
Score = 698 bits (1801), Expect = 0.0, Method: Composition-based stats.
Identities = 334/537 (62%), Positives = 419/537 (78%), Gaps = 8/537 (1%)
Query: 19 FVPLLPHLHHKDTEYTLV--TKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F P PH H TE+ V ++ YV V ++LKV LT+LA RA DV HF
Sbjct: 35 FQPTDPH--HHQTEFAKVEGSEKYVEEVEVFG--RKVLKVNPEALTILAHRAFSDVHHFF 90
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
R HL R EDPEASDNDR+VA+ L+KNA IAA R+LP CQDTGTAI+ G +GE +
Sbjct: 91 RKDHLEGWRRAIEDPEASDNDRYVAMTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCW 150
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFF 196
T G+DE+ LS+G+ + Y NLRYSQ L M+ E NTG NLPAQ+DL A G +YEF F
Sbjct: 151 TGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLF 210
Query: 197 VAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTM 256
+AKGGGSANKA+L+QETK++LNPKSLR F+EEK+ T+GT+ACPPYH+A+V+GGTSAEMTM
Sbjct: 211 IAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTM 270
Query: 257 KAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVI 316
K VK ASC+Y D LPT D+ G +RD E E++VM++ + G+GAQFGGKYFAH ARVI
Sbjct: 271 KTVKLASCRYYDSLPTTGDKY-GRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVI 329
Query: 317 RMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVK 376
R+PRHGASCP+G+ VSCSADRQ LA INK GI++E+LE +PA+YLP++ E + L V
Sbjct: 330 RLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDIPEVR-LSTTSVN 388
Query: 377 IDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVY 436
+DL P+D++R +LS++PV TR+ L GT+IVARDIAHA+++EM++N +PLP+Y+K P+Y
Sbjct: 389 VDLKRPIDEVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIY 448
Query: 437 YAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGF 496
YAGPAK PE ASGSFGPTTAGRMD +VDLFQ++GGS++ LAKGNRSK+VT+ACKK+GGF
Sbjct: 449 YAGPAKTPEGHASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGF 508
Query: 497 YLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQ 553
YLGSIGGPAA+LA DSI++V L ELGMEAVWKIEVE+FPAFIVVDDKGND + +
Sbjct: 509 YLGSIGGPAAILAKDSIKEVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSK 565
>ref|XP_001566537.1| fumarate hydratase, putative [Leishmania braziliensis
MHOM/BR/75/M2904]
emb|CAM40049.1| fumarate hydratase, putative [Leishmania braziliensis]
Length = 568
Score = 697 bits (1800), Expect = 0.0, Method: Composition-based stats.
Identities = 333/539 (61%), Positives = 423/539 (78%), Gaps = 10/539 (1%)
Query: 19 FVPLLPHLHHKDTEYTLV--TKDYVS-VVNPGAGLPEILKVEAAGLTLLASRAIGDVQHF 75
F P PH H +T++T + ++ YV VV G E+LKV LT++A RA DV HF
Sbjct: 35 FQPTDPH--HHETQFTKIEGSEKYVEEVVVFGR---EVLKVNPEALTIVAHRAYSDVHHF 89
Query: 76 LRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQV 135
R HL R +DPE+SDNDR+VA+ L+KNA IAA R+LP CQDTGTAI+ G +GE
Sbjct: 90 FRKDHLEGWRRAIDDPESSDNDRYVAMTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELC 149
Query: 136 FTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFF 195
+T G+DE+ LS+GV + Y NLRYSQ L M+ E NTG NLPAQ+DL A G YEF
Sbjct: 150 WTGGEDEKYLSKGVWNAYKYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSGYEFL 209
Query: 196 FVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMT 255
F+AKGGGSANKA+L+QETK++LNPKSLR F+EEK+ T+GT+ACPPYH+A+V+GGTSAEMT
Sbjct: 210 FIAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMT 269
Query: 256 MKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARV 315
MK VK ASC+Y D LPT D+ G +RDLE E +VM++ + G+GAQFGGKYFAH ARV
Sbjct: 270 MKTVKLASCRYYDSLPTTGDK-HGRAFRDLEWEAVVMEVAQKSGIGAQFGGKYFAHQARV 328
Query: 316 IRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPV 375
IR+PRHGASCP+G+ VSCSADRQ LA+INK+GI++E+LE +PA+YLP++T L V
Sbjct: 329 IRLPRHGASCPVGLAVSCSADRQILAQINKNGIYIEQLEENPAQYLPDITTAN-LSTTSV 387
Query: 376 KIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPV 435
+DL P+D++R +LS++PV TR+ L GT+IVARD AHA+++E+L++ +PLPDY+K P+
Sbjct: 388 NVDLKRPIDEVRRQLSQYPVGTRVMLNGTLIVARDTAHAKIKEILDSGEPLPDYMKTSPI 447
Query: 436 YYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGG 495
YYAGPAK PE ASGSFGPTTAGRMD +VDLFQ++GGS +MLAKGNRSK+VT+ACKK+GG
Sbjct: 448 YYAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSHIMLAKGNRSKQVTDACKKHGG 507
Query: 496 FYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQL 554
FYLGSIGGPAA+LA DSI++V+ + ELGMEAVWKIEV +FPAFI+VDDKGND F ++
Sbjct: 508 FYLGSIGGPAAILAKDSIKEVKCIAFPELGMEAVWKIEVVDFPAFIIVDDKGNDMFSKM 566
>gb|ABF20402.1| fumarate hydratase [Leishmania tropica]
Length = 568
Score = 697 bits (1799), Expect = 0.0, Method: Composition-based stats.
Identities = 333/537 (62%), Positives = 416/537 (77%), Gaps = 8/537 (1%)
Query: 19 FVPLLPHLHHKDTEYTLV--TKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F P PH H TE+ V ++ YV V ++LKV LT+LA RA DV HF
Sbjct: 35 FQPTDPH--HHQTEFAKVEGSEKYVEEVEVFG--RQVLKVNPEALTILAHRAFSDVHHFF 90
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
R HL R EDPEASDNDR+VA L+KNA IAA R+LP CQDTGTAI+ G +GE +
Sbjct: 91 RKDHLEGWRRAIEDPEASDNDRYVATTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCW 150
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFF 196
T G+DE+ LS+G+ + Y NLRYSQ L M+ E NTG NLPAQ+DL A G +YEF F
Sbjct: 151 TGGEDEKCLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLF 210
Query: 197 VAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTM 256
+AKGGGSANKA+L+QETK++LNPKSLR F+EEK+ T+GT+ACPPYH+A+V+GGTSAEMTM
Sbjct: 211 IAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTM 270
Query: 257 KAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVI 316
K VK ASC+Y D LPT D+ G +RD E E++VM++ + G+GAQFGGKYFAH ARVI
Sbjct: 271 KTVKLASCRYYDSLPTTGDKY-GRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVI 329
Query: 317 RMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVK 376
R+PRHGASCP+G+ VSCSADRQ LA INK GI++E+LE +PA+YLP++ E L V
Sbjct: 330 RLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDIPEAH-LSTTSVN 388
Query: 377 IDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVY 436
+ L P+D++R +LS++PV TR+ L GT+IVARDIAHA+++EM++N +PLP+Y+K P+Y
Sbjct: 389 VXLKRPIDEVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIY 448
Query: 437 YAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGF 496
YAGPAK PE ASGSFGPTTAGRMD +VDLFQ++GGS++ LAKGNRSK+VT+ACKK+GGF
Sbjct: 449 YAGPAKTPEGYASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGF 508
Query: 497 YLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQ 553
YLGSIGGPAA+LA DSI++V L ELGMEAVWKIEVE+FPAFIVVDDKGND + +
Sbjct: 509 YLGSIGGPAAILAKDSIKQVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSK 565
>ref|ZP_03859476.1| fumarase [Kribbella flavida DSM 17836]
gb|EEJ19446.1| fumarase [Kribbella flavida DSM 17836]
Length = 554
Score = 697 bits (1799), Expect = 0.0, Method: Composition-based stats.
Identities = 345/543 (63%), Positives = 419/543 (77%), Gaps = 8/543 (1%)
Query: 17 FKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F + LLP L DTEY L+T + VS AG L+VE + L L + A+ D+ H+L
Sbjct: 5 FTYSDLLP-LGQDDTEYRLLTTEGVSTFT--AGGRTFLQVEPSVLRALTAEAMHDISHYL 61
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
R +HLA LR I +DPEAS NDRFVAL L+KNANI+A ILP CQDTGTAI+ G K E V
Sbjct: 62 RSAHLAQLRRIIDDPEASGNDRFVALDLLKNANISAGGILPMCQDTGTAIVMGKKSEGVL 121
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE---YE 193
T DEE +SRGVH YT NLRYSQ PLTM+DEKNTG NLPAQI+LY+T G Y+
Sbjct: 122 TGAVDEEWISRGVHDAYTKLNLRYSQMAPLTMWDEKNTGTNLPAQIELYSTPGTTDPAYK 181
Query: 194 FFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAE 253
F F+AKGGGSANK+FLFQETK+VLNP + FL+EKI ++GT+ACPPYH+A+VVGGTSAE
Sbjct: 182 FLFMAKGGGSANKSFLFQETKAVLNPAGMMKFLDEKIRSLGTAACPPYHLAIVVGGTSAE 241
Query: 254 MTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDA 313
+K KYAS YLD LPT G+ +RD+E+E+ V + ++ G+GAQFGGKYF HD
Sbjct: 242 YALKTAKYASAHYLDALPTT-GSPLGHGFRDVELEEKVFQLTQDFGIGAQFGGKYFCHDV 300
Query: 314 RVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK-V 372
RVIR+PRHGASCP+ I VSCSADRQA AKI G+++E+LE DPA++LP+ T++QL
Sbjct: 301 RVIRLPRHGASCPVAIAVSCSADRQARAKITPAGVFLEQLERDPARFLPDTTDEQLNDDA 360
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V+IDLN PM +IRAELS+ PVKTRLSL+G ++VARDIAHA+++E L+ +P+P Y+++
Sbjct: 361 DVVRIDLNQPMSEIRAELSKLPVKTRLSLSGPLVVARDIAHAKIKERLDAGEPMPGYLRD 420
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
H VYYAGPAK PE ASGSFGPTTAGRMD +VD FQA GGSFVMLAKGNRS +VTEAC+K
Sbjct: 421 HAVYYAGPAKTPEGYASGSFGPTTAGRMDAYVDQFQAAGGSFVMLAKGNRSAKVTEACRK 480
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA LA D I+ VEV++ ELGMEAVWKIEVE+FPAF+VVDDKGNDFF
Sbjct: 481 HGGFYLGSIGGPAARLAQDCIKSVEVIEYAELGMEAVWKIEVEDFPAFVVVDDKGNDFFT 540
Query: 553 QLR 555
R
Sbjct: 541 DTR 543
>gb|ABF20401.1| fumarate hydratase [Leishmania infantum]
Length = 568
Score = 697 bits (1799), Expect = 0.0, Method: Composition-based stats.
Identities = 333/537 (62%), Positives = 419/537 (78%), Gaps = 8/537 (1%)
Query: 19 FVPLLPHLHHKDTEYTLV--TKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F P PH H TE+ V ++ YV V ++LKV LT+LA RA DV HF
Sbjct: 35 FQPTDPH--HHQTEFAKVEGSEKYVEEVEVFG--RKVLKVNPEALTILAHRAFSDVHHFF 90
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
R HL R EDPEASDNDR+VA+ L+KNA IAA R+LP CQDTGTAI+ G +GE +
Sbjct: 91 RKDHLEGWRRAIEDPEASDNDRYVAMTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCW 150
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFF 196
T G+DE+ LS+G+ + Y NLRYSQ L M+ E NTG NLPAQ+DL A G +YEF F
Sbjct: 151 TGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLF 210
Query: 197 VAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTM 256
+AKGGGSANKA+L+QETK++LNPKSLR F+EEK+ T+GT+ACPPYH+A+V+GGTSAEMTM
Sbjct: 211 IAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTM 270
Query: 257 KAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVI 316
K VK ASC+Y D LPT D+ G +RD E E++VM++ + G+GAQFGGKYFAH ARVI
Sbjct: 271 KTVKLASCRYYDSLPTTGDKY-GRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVI 329
Query: 317 RMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVK 376
R+PRHGASCP+G+ VSCSADRQ LA IN+ GI++E+LE +PA+YLP++ E + L V
Sbjct: 330 RLPRHGASCPVGLAVSCSADRQILAHINQSGIYIEQLEQNPAQYLPDIPEVR-LSTTSVN 388
Query: 377 IDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVY 436
+DL P+D++R +LS++PV TR+ L GT+IVARDIAHA+++EM++N +PLP+Y+K P+Y
Sbjct: 389 VDLKRPIDEVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIY 448
Query: 437 YAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGF 496
YAGPAK PE ASGSFGPTTAGRMD +VDLFQ++GGS++ LAKGNRSK+VT+ACKK+GGF
Sbjct: 449 YAGPAKTPEGHASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGF 508
Query: 497 YLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQ 553
YLGSIGGPAA+LA DSI++V L ELGMEAVWKIEVE+FPAFIVVDDKGND + +
Sbjct: 509 YLGSIGGPAAILAKDSIKEVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSK 565
>gb|ABF20395.1| fumarate hydratase [Leishmania infantum]
Length = 568
Score = 697 bits (1799), Expect = 0.0, Method: Composition-based stats.
Identities = 334/537 (62%), Positives = 419/537 (78%), Gaps = 8/537 (1%)
Query: 19 FVPLLPHLHHKDTEYTLV--TKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F P PH H TE+ V ++ YV V ++LKV LT+LA RA DV HF
Sbjct: 35 FQPTDPH--HHQTEFAKVEGSEKYVEEVEVFG--RKVLKVNPEALTILAHRAFSDVHHFF 90
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
R HL R EDPEASDNDR+VA+ L+KNA IAA R+LP CQDTGTAI+ G +GE +
Sbjct: 91 RKDHLEGWRRAIEDPEASDNDRYVAMTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCW 150
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFF 196
T G+DE+ LS+G+ + Y NLRYSQ L M+ E NTG NLPAQ+DL A G +YEF F
Sbjct: 151 TGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLF 210
Query: 197 VAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTM 256
+AKGGGSANKA+L+QETK++LNPKSLR F+EEK+ T+GT+ACPPYH+A+V+GGTSAEMTM
Sbjct: 211 IAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTM 270
Query: 257 KAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVI 316
K VK ASC+Y D LPT D+ G +RD E E++VM++ + G+GAQFGGKYFAH ARVI
Sbjct: 271 KTVKLASCRYYDSLPTTGDKY-GRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVI 329
Query: 317 RMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVK 376
R+PRHGASCP+G+ VSCSADRQ LA INK GI++E+LE +PA+YLP++ E + L V
Sbjct: 330 RLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDIPEVR-LSTTSVN 388
Query: 377 IDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVY 436
+DL P+D++R +LS++PV TR+ L GT+IVARDIAHA+++EM++N +PLP+Y+K P+Y
Sbjct: 389 VDLKRPIDEVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKMSPIY 448
Query: 437 YAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGF 496
YAGPAK PE ASGSFGPTTAGRMD +VDLFQ++GGS++ LAKGNRSK+VT+ACKK+GGF
Sbjct: 449 YAGPAKTPEGHASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGF 508
Query: 497 YLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQ 553
YLGSIGGPAA+LA DSI++V L ELGMEAVWKIEVE+FPAFIVVDDKGND + +
Sbjct: 509 YLGSIGGPAAILAKDSIKEVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSK 565
>ref|ZP_02297379.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Rhizobium leguminosarum bv. trifolii WSM1325]
gb|EDR74243.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Rhizobium leguminosarum bv. trifolii WSM1325]
Length = 535
Score = 696 bits (1796), Expect = 0.0, Method: Composition-based stats.
Identities = 343/524 (65%), Positives = 408/524 (77%), Gaps = 4/524 (0%)
Query: 31 TEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFLRPSHLASLRSIFED 90
T Y ++ D+VSV EIL VE G+ LLA A D+ H LRP HL L SI +D
Sbjct: 13 TPYRKLSGDHVSVDTFKG--QEILTVEPEGIRLLAETAFADINHLLRPGHLKQLASILDD 70
Query: 91 PEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVFTNGDDEEALSRGVH 150
PEA+DNDRFVA L+KNANIAA +LP CQDTGTAII G KG +V+T G+D AL+RGV
Sbjct: 71 PEATDNDRFVAYDLLKNANIAAGGVLPMCQDTGTAIIMGKKGRRVWTEGEDTAALARGVM 130
Query: 151 HIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFFVAKGGGSANKAFLF 210
Y NLRYSQ P+ M++EKNT NLPAQID+Y YEF FVAKGGGSANK FL+
Sbjct: 131 DAYEKKNLRYSQLAPVKMFEEKNTRNNLPAQIDIYEEGTDAYEFLFVAKGGGSANKTFLY 190
Query: 211 QETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTMKAVKYASCKYLDEL 270
Q T S+L + +FL+EKI T+GT+ACPPYH+A+V+GGTSAEM +K VK AS +YLDEL
Sbjct: 191 QGTPSLLTHDRMIDFLKEKILTLGTAACPPYHLAIVIGGTSAEMNLKTVKLASTRYLDEL 250
Query: 271 PTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVIRMPRHGASCPIGIG 330
PT+ ES G+ +RD+EME + + + +G+GAQFGGKYF HD RVIR+PRHGAS PIG+G
Sbjct: 251 PTEGSES-GHAFRDIEMETEIHKLTQQMGVGAQFGGKYFCHDVRVIRLPRHGASLPIGLG 309
Query: 331 VSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVKIDLNMPMDKIRAEL 390
VSCSADRQA +I +DGI+VE+LE DP+KYLPE+ E +L + V+IDLN PM + AEL
Sbjct: 310 VSCSADRQAKGRITRDGIFVEQLETDPSKYLPEIDEAKLSE-STVRIDLNRPMADVLAEL 368
Query: 391 SRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVYYAGPAKRPEALASG 450
SRHPVKTRLSL+GTIIVARD+AHA++RE LE + +PDY+KNHPVYYAGPAK P ASG
Sbjct: 369 SRHPVKTRLSLSGTIIVARDLAHAKIRERLEKGEGMPDYLKNHPVYYAGPAKTPVGYASG 428
Query: 451 SFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGFYLGSIGGPAALLAM 510
SFGPTTAGRMD +VD FQ+ GGS VMLAKGNRS+ V EACKK+GGFYLGSIGGPAA LA
Sbjct: 429 SFGPTTAGRMDSYVDQFQSFGGSMVMLAKGNRSRAVREACKKHGGFYLGSIGGPAARLAQ 488
Query: 511 DSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQL 554
D IRKVEV + ELGMEAVWKIEVE+FPAFIV+DDKGNDFFQ+L
Sbjct: 489 DCIRKVEVFEYPELGMEAVWKIEVEDFPAFIVIDDKGNDFFQEL 532
>gb|ABF20376.1| fumarate hydratase [Leishmania infantum]
Length = 568
Score = 696 bits (1796), Expect = 0.0, Method: Composition-based stats.
Identities = 333/537 (62%), Positives = 418/537 (77%), Gaps = 8/537 (1%)
Query: 19 FVPLLPHLHHKDTEYTLV--TKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F P PH H TE+ V ++ YV V ++LKV LT+LA RA DV HF
Sbjct: 35 FQPTDPH--HHQTEFAKVEGSEKYVEEVEVFG--RKVLKVNPEALTILAHRAFSDVHHFF 90
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
R HL R EDPEASDNDR+VA+ L+KNA IAA R+LP CQDTGTAI+ G +GE +
Sbjct: 91 RKDHLEGWRRAIEDPEASDNDRYVAMTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCW 150
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFF 196
T G+DE+ LS+G+ + Y NLRYSQ L M+ E NTG NLPAQ+DL A G +YEF F
Sbjct: 151 TGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLF 210
Query: 197 VAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTM 256
+AKGGGSANKA+L+QETK++LNPKSLR F+EEK+ T+GT+ACPPYH+A+V+GGTSAEMTM
Sbjct: 211 IAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTM 270
Query: 257 KAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVI 316
K VK ASC+Y D LPT D+ G +RD E E++VM++ + G+GAQFGGKYFAH ARVI
Sbjct: 271 KTVKLASCRYYDSLPTTGDKY-GRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVI 329
Query: 317 RMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVK 376
R+PRHGASCP+G+ VSCSADRQ LA INK GI++E+LE +PA+YLP++ E + L V
Sbjct: 330 RLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDIPEVR-LSTTSVN 388
Query: 377 IDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVY 436
+DL P+D++R +LS++PV TR+ L GT+IVARDIAHA+++EM++N +PLP+Y+K P+Y
Sbjct: 389 VDLKRPIDEVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIY 448
Query: 437 YAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGF 496
YAGPAK PE ASGSFGPTTAGRMD +VDLFQ++GGS++ LAKGNRSK+V +ACKK+GGF
Sbjct: 449 YAGPAKTPEGHASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVXDACKKHGGF 508
Query: 497 YLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQ 553
YLGSIGGPAA+LA DSI++V L ELGMEAVWKIEVE+FPAFIVVDDKGND + +
Sbjct: 509 YLGSIGGPAAILAKDSIKEVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSK 565
>ref|YP_001438056.1| hypothetical protein ESA_01967 [Enterobacter sakazakii ATCC
BAA-894]
gb|ABU77220.1| hypothetical protein ESA_01967 [Enterobacter sakazakii ATCC
BAA-894]
Length = 548
Score = 696 bits (1795), Expect = 0.0, Method: Composition-based stats.
Identities = 335/543 (61%), Positives = 421/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L +TEY L+T+D+VSV EILKVE LTLLA A D
Sbjct: 2 SGKPFFWQEPFP-LKKDETEYYLLTRDHVSVSEFEG--QEILKVEPQALTLLARHAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N+ IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILSDPEASENDKYVALQFLRNSEIAAKGILPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL++GV+ YT NLRYSQN L MY E NTG NLPAQIDLY+ G EY
Sbjct: 119 QRVWTGGGDEAALAQGVYQTYTQDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+ +L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKAYLVEKMRTLGTAACPPYHVAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD+++E+ ++ RN+G+GAQFGGKYFAHD
Sbjct: 239 EATLKTVKLASTKYYDGLPTEGNE-HGQAFRDVQLEEELLQEARNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +P KY+PE + +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLESNPGKYIPEALR-RAGEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL+GTIIVARDIAHA+++E +++ LP Y+K+
Sbjct: 357 EAVRVDLNRPMSEILAQLSQYPVSTRLSLSGTIIVARDIAHAKLKERIDSGAGLPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL QANGGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQANGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SIR +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIRHLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|ZP_03922648.1| fumarate hydratase class I [Mobiluncus curtisii ATCC 43063]
gb|EEI89235.1| fumarate hydratase class I [Mobiluncus curtisii ATCC 43063]
Length = 555
Score = 695 bits (1794), Expect = 0.0, Method: Composition-based stats.
Identities = 338/542 (62%), Positives = 423/542 (78%), Gaps = 7/542 (1%)
Query: 17 FKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F + +LPH T Y +T + VS V G + LKV LTLL+ A D+ H+L
Sbjct: 4 FFYADILPHGEDTYT-YRKLTSEGVSEVE-GPDGTKFLKVSPEALTLLSETAFHDISHYL 61
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
R +HL LR I +DPEAS ND+FVA+ L++NANIAAA +LP CQDTGTAII G +G++V
Sbjct: 62 RTAHLQQLRKILDDPEASGNDKFVAMDLLRNANIAAAGVLPMCQDTGTAIIKGERGQRVL 121
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKG----CEY 192
T G DEEALSRGV++ YT NLRYSQN PL+MY+EKNTGCNLPAQ++LYA EY
Sbjct: 122 TPGPDEEALSRGVYNAYTKLNLRYSQNSPLSMYEEKNTGCNLPAQVELYAETAPGHEAEY 181
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
F F+AKGGGSANK++L+Q TK++L+P+ + FLEEKI ++GT+ACPPYH+A+V+GGTSA
Sbjct: 182 RFLFMAKGGGSANKSYLYQMTKAILDPEHMMQFLEEKIRSLGTAACPPYHLAIVIGGTSA 241
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K KYAS YLD LPT E + +RDLEME+ V+D+ R++G+GAQFGGKYF HD
Sbjct: 242 EYALKTAKYASAHYLDGLPTHGGE-QAQGFRDLEMEEQVLDMTRHMGIGAQFGGKYFCHD 300
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RV+R+PRHGAS P+ I VSCSADRQ +AKINKDG+++E L+ DP +++P+ +E +L
Sbjct: 301 VRVVRLPRHGASLPVAIAVSCSADRQCVAKINKDGVFIEALDTDPGRFMPDPSEAELGGD 360
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VKIDLN PM + AEL+++P+KTRLSLTGT+IVARDIAHAR+R+ LE LP Y K+
Sbjct: 361 EAVKIDLNRPMKDVLAELTKYPIKTRLSLTGTLIVARDIAHARLRDRLEKEGDLPQYFKD 420
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HPVYYAGPAK PE + SGSFGPTTA RMDP+VDLFQA+GGS +MLAKGNR + VT+AC+K
Sbjct: 421 HPVYYAGPAKTPEGMPSGSFGPTTASRMDPYVDLFQAHGGSMIMLAKGNRGQVVTDACRK 480
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA LA SI+KVEVL+ ELGMEAVWKI+VE+FPAFIVVDDKGN+FF+
Sbjct: 481 HGGFYLGSIGGPAAELAAHSIKKVEVLEYPELGMEAVWKIDVEDFPAFIVVDDKGNNFFE 540
Query: 553 QL 554
L
Sbjct: 541 GL 542
>gb|ACO63163.1| putative fumarate hydratase class1-malate <=> fumarate + H(2)O
[Micromonas sp. RCC299]
Length = 575
Score = 695 bits (1794), Expect = 0.0, Method: Composition-based stats.
Identities = 333/539 (61%), Positives = 417/539 (77%), Gaps = 4/539 (0%)
Query: 16 PFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHF 75
PF + L KD + +T ++VSVV A ++LKVE + LLA A+ D+ H
Sbjct: 37 PFHYQDLFEPGSPKDVPWRKITSEHVSVVE--AAGRKVLKVEPEAIRLLAQEAMTDIAHL 94
Query: 76 LRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQV 135
LRP HL L +I +DPEASDNDRFVAL+L+KNAN+AA +LPGCQDTGTAII G +G+ V
Sbjct: 95 LRPGHLQQLANILKDPEASDNDRFVALELLKNANVAAGMVLPGCQDTGTAIIMGKRGQNV 154
Query: 136 FTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFF 195
+T+G+DEE +S+GV+ Y NLRYSQ P TM+DEKNTG NLPAQIDLYA G EY F
Sbjct: 155 WTDGNDEEMISKGVYDTYVKRNLRYSQVAPQTMFDEKNTGSNLPAQIDLYAKDGDEYHFH 214
Query: 196 FVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMT 255
F+AKGGGSANK FL+QETK++LNP+ + FLEEKI T+GT+ACPPYH+A VVGG SAE
Sbjct: 215 FMAKGGGSANKTFLYQETKALLNPERMVQFLEEKIKTLGTAACPPYHLAFVVGGLSAEQN 274
Query: 256 MKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARV 315
+K VK AS +Y D+L T + + G +RDLEME + ++ R +G+GAQFGGKYF HD RV
Sbjct: 275 LKTVKMASARYYDDLHTSGN-AHGRAFRDLEMEAQIHELTRRMGIGAQFGGKYFCHDVRV 333
Query: 316 IRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPP- 374
+R+PRHGASCP+G+GVSCSADRQAL KI G++VE LE DP+++LP+VT+D L P
Sbjct: 334 VRLPRHGASCPVGLGVSCSADRQALGKITSQGVFVEALETDPSRFLPDVTDDHLDPSGPV 393
Query: 375 VKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHP 434
V +DL PM +IR LS V TRL LTG +IVARDIAHA+++E L+ + +P Y+K+H
Sbjct: 394 VDVDLTRPMSEIRERLSACSVSTRLRLTGPLIVARDIAHAKIKERLDAGEEMPAYMKDHA 453
Query: 435 VYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYG 494
VYYAGPAK P+ +ASGSFGPTTAGRMD +VD FQA GGS VMLAKGNRS +VT ACKK+G
Sbjct: 454 VYYAGPAKTPDGMASGSFGPTTAGRMDSYVDAFQAAGGSMVMLAKGNRSAQVTRACKKHG 513
Query: 495 GFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQ 553
GFYLGSIGGPAA+LA ++I+KV+VL+ ELGMEA+WKIEVE+FPAF++VDDKGNDFF++
Sbjct: 514 GFYLGSIGGPAAILAQNNIKKVDVLEFPELGMEAIWKIEVEDFPAFVIVDDKGNDFFKK 572
>ref|XP_844042.1| fumarate hydratase, putative [Trypanosoma brucei]
gb|AAX79304.1| fumarate hydratase, putative [Trypanosoma brucei]
gb|AAZ10483.1| fumarate hydratase, putative [Trypanosoma brucei]
Length = 565
Score = 695 bits (1794), Expect = 0.0, Method: Composition-based stats.
Identities = 334/536 (62%), Positives = 415/536 (77%), Gaps = 6/536 (1%)
Query: 19 FVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFLRP 78
F P PH H TEY + DYV + ++L V+ LT+LA A DV H+ R
Sbjct: 35 FQPSDPH--HDKTEYYNIPGDYVKEIEVMG--RKVLSVDPTALTVLAQHAFTDVHHYFRE 90
Query: 79 SHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVFTN 138
HL+ R + +DPEA+DNDRFVA L++NA +AA RILP CQDTGTAI+ G +GE +T
Sbjct: 91 DHLSGWRRVLDDPEATDNDRFVATTLLQNACVAAGRILPACQDTGTAIVLGKRGELCWTG 150
Query: 139 GDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFFVA 198
G+DE+ LS G+ Y + NLRYSQ L M+ E NTG NLPAQ+DL A G EY F FVA
Sbjct: 151 GEDEKYLSHGIWKCYVSRNLRYSQTAALDMFKEANTGDNLPAQMDLMAVPGNEYHFLFVA 210
Query: 199 KGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTMKA 258
KGGGSANKAFL+Q+TK++LNPKSLR F+EEK+ T+GTSACPPYH+A+V+GGTSAEMTMK
Sbjct: 211 KGGGSANKAFLYQQTKALLNPKSLRAFVEEKLKTLGTSACPPYHIALVIGGTSAEMTMKT 270
Query: 259 VKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVIRM 318
VK ASC+Y D LPT ++S G +RD+E E++++++ RN+G+GAQFGGKYFAH RVIR+
Sbjct: 271 VKLASCRYYDSLPTTGNKS-GRAFRDIEWEEIILEMTRNLGIGAQFGGKYFAHQIRVIRL 329
Query: 319 PRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVKID 378
PRHGASCP+G+GVSCSADRQ L KI +G+++EKL DPAKYLP+V L V++D
Sbjct: 330 PRHGASCPVGLGVSCSADRQILGKITSEGVFLEKLVRDPAKYLPDVPLTSLGN-GTVEVD 388
Query: 379 LNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVYYA 438
L+ PM KIR L+++PV TRLSLTG +IVARDIAHA++ E L ++PLP Y+K+HP+YYA
Sbjct: 389 LHQPMSKIRELLTQYPVTTRLSLTGPLIVARDIAHAKIMERLNADEPLPQYMKDHPIYYA 448
Query: 439 GPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGFYL 498
GPAK P+ +ASGSFGPTTAGRMD +V F A GGSFV LAKGNRSK VT+ACKKYGGFYL
Sbjct: 449 GPAKTPKGMASGSFGPTTAGRMDSYVAPFMAAGGSFVTLAKGNRSKVVTDACKKYGGFYL 508
Query: 499 GSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQL 554
GSIGGPAA+LA D+I+KVEV++ ELGMEAVW+IEV NFPAFI+VDDKGNDF+ +L
Sbjct: 509 GSIGGPAAILARDNIKKVEVVEYPELGMEAVWRIEVVNFPAFIIVDDKGNDFYAKL 564
>ref|XP_821204.1| fumarate hydratase, putative [Trypanosoma cruzi strain CL Brener]
gb|EAN99353.1| fumarate hydratase, putative [Trypanosoma cruzi]
Length = 565
Score = 695 bits (1794), Expect = 0.0, Method: Composition-based stats.
Identities = 338/544 (62%), Positives = 413/544 (75%), Gaps = 6/544 (1%)
Query: 13 SAPPFKFVPLL--PHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIG 70
SA F + P+ HH +TEY ++ DY+ V IL+V+ LT LA +A
Sbjct: 25 SASEFHYEPIFQPSDPHHDETEYYMLEGDYIKTVEILG--KTILQVKPEALTALAQQAFA 82
Query: 71 DVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGY 130
DV HF R HL R I EDPEAS+NDRFVA L++NA +AA R+LP CQDTGTAI+ G
Sbjct: 83 DVHHFFRKDHLFGWRRILEDPEASNNDRFVAHTLLQNACVAAGRVLPACQDTGTAIVLGK 142
Query: 131 KGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGC 190
+GE +T G+DE+ LS+G+ Y LRYSQ L M+ E NTG NLPAQ DL AT G
Sbjct: 143 RGELCWTGGEDEKHLSKGIWDCYMNRYLRYSQTAALDMFKEVNTGNNLPAQFDLLATAGN 202
Query: 191 EYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGT 250
EY F F+AKGGGSANKAFL+QETK++LNPKSLR F+E+K+ T+GT+ACPPYH+A+V+GGT
Sbjct: 203 EYHFLFIAKGGGSANKAFLYQETKALLNPKSLREFIEQKLKTLGTAACPPYHIALVIGGT 262
Query: 251 SAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFA 310
SAEMTMK VK ASC+Y D LPT +++ G +RDLE E +VMDI G+GAQFGGKYFA
Sbjct: 263 SAEMTMKTVKLASCRYYDSLPTTGNKN-GRAFRDLEWEAIVMDIACKSGIGAQFGGKYFA 321
Query: 311 HDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLL 370
H ARVIR+PRHGASCP+G+GVSCSADRQ LAKI G++VE+L DPA+YLP++ L
Sbjct: 322 HQARVIRLPRHGASCPVGLGVSCSADRQILAKITPKGVFVERLVRDPAQYLPDLPPSS-L 380
Query: 371 KVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYI 430
V ++LN PM +IR LS++PV TRLSLTGT+IVARDIAHA++ E L NN+ LP Y+
Sbjct: 381 STNVVNVNLNQPMSEIRKLLSQYPVTTRLSLTGTLIVARDIAHAKIMERLNNNEELPQYM 440
Query: 431 KNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEAC 490
K+HPVYYAGPAK P+ +ASGSFGPTTAGRMD ++ F A GGSFV LAKGNRSK VTEAC
Sbjct: 441 KDHPVYYAGPAKTPKGMASGSFGPTTAGRMDSYLCPFMAAGGSFVTLAKGNRSKAVTEAC 500
Query: 491 KKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDF 550
KKYGGFYLGSIGG AA+LA ++I+ VEV++ ELGMEAVW+I+V +FPAFIVVDDKGNDF
Sbjct: 501 KKYGGFYLGSIGGSAAILAQNNIKNVEVVEFPELGMEAVWRIDVVDFPAFIVVDDKGNDF 560
Query: 551 FQQL 554
F +L
Sbjct: 561 FSKL 564
>ref|YP_001335177.1| fumarase A (fumarate hydratase class I), aerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
gb|ABR76947.1| fumarase A (fumarate hydratase class I), aerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
Length = 548
Score = 695 bits (1794), Expect = 0.0, Method: Composition-based stats.
Identities = 333/543 (61%), Positives = 422/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L++ DYVSV E+LKV+ LTLLA A D
Sbjct: 2 SNKPFVYQDPFP-LKKDDTEYYLLSSDYVSVAEFAG--QEVLKVDPQALTLLAQHAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILNDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL++GV++ Y NLRYSQN PL MY E NTG NLPAQIDLYAT G EY
Sbjct: 119 QRVWTGGGDEAALAQGVYNTYIQDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYATDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK+++ P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALITPAKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD++MEQ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 EATLKTVKLASTKYYDGLPTEGNE-HGQAFRDVQMEQELLLEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +P KY+PE Q +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLESNPGKYIPEHLR-QAGEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK++LN PM +I A+LS++PV TRLSL+GTIIVARDIAHA+++E+++N + LP Y+K+
Sbjct: 357 EAVKVNLNQPMSEILAQLSQYPVSTRLSLSGTIIVARDIAHAKLKELIDNGEALPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P+ ASGS GPTTAGRMD +VDL Q++G S +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPDGYASGSLGPTTAGRMDSYVDLLQSHGASKIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKSLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>gb|ABF20398.1| fumarate hydratase [Leishmania donovani archibaldi]
Length = 568
Score = 695 bits (1793), Expect = 0.0, Method: Composition-based stats.
Identities = 333/537 (62%), Positives = 418/537 (77%), Gaps = 8/537 (1%)
Query: 19 FVPLLPHLHHKDTEYTLV--TKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDVQHFL 76
F P PH H TE+ V ++ YV V ++LKV LT+LA RA DV HF
Sbjct: 35 FQPTDPH--HHQTEFAKVEGSEKYVEEVEVFG--RKVLKVNPEALTILAHRAFSDVHHFF 90
Query: 77 RPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKGEQVF 136
R HL R EDPEASDNDR+VA+ L+KNA IAA R+LP CQDTGTAI+ G +GE +
Sbjct: 91 RKDHLEGWRRAIEDPEASDNDRYVAMTLLKNACIAAGRVLPSCQDTGTAIVLGKRGELCW 150
Query: 137 TNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEYEFFF 196
T G+DE+ LS+G+ + Y NLRYSQ L M+ E NTG NLPAQ+DL A G +YEF F
Sbjct: 151 TGGEDEKYLSKGIWNAYRYHNLRYSQTAALDMFKECNTGDNLPAQLDLLAVPGSDYEFLF 210
Query: 197 VAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSAEMTM 256
+AKGGGSANKA+L+QETK++LNPKSLR F+EEK+ T+GT+ACPPYH+A+V+GGTSAEMTM
Sbjct: 211 IAKGGGSANKAYLYQETKALLNPKSLRAFIEEKLKTLGTAACPPYHIALVIGGTSAEMTM 270
Query: 257 KAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHDARVI 316
K VK ASC+Y D LPT D+ G +RD E E++VM++ + G+GAQFGGKYFAH ARVI
Sbjct: 271 KTVKLASCRYYDSLPTTGDKY-GRAFRDPEWEKIVMEVAQKSGIGAQFGGKYFAHQARVI 329
Query: 317 RMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKVPPVK 376
R+PRHGASCP+G+ VSCSADRQ LA INK GI++E+LE +PA+YLP++ E + L V
Sbjct: 330 RLPRHGASCPVGLAVSCSADRQILAHINKSGIYIEQLEQNPAQYLPDIPEVR-LSTTSVN 388
Query: 377 IDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKNHPVY 436
+ L P+D++R +LS++PV TR+ L GT+IVARDIAHA+++EM++N +PLP+Y+K P+Y
Sbjct: 389 VGLKRPIDEVRQQLSQYPVGTRVMLNGTLIVARDIAHAKIKEMMDNGEPLPEYMKTSPIY 448
Query: 437 YAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKKYGGF 496
YAGPAK PE ASGSFGPTTAGRMD +VDLFQ++GGS++ LAKGNRSK+VT+ACKK+GGF
Sbjct: 449 YAGPAKTPEGHASGSFGPTTAGRMDSYVDLFQSHGGSYITLAKGNRSKQVTDACKKHGGF 508
Query: 497 YLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQQ 553
YLGSIGGPAA+LA DSI++V L ELGMEAVWKIEVE+FPAFIVVDDKGND + +
Sbjct: 509 YLGSIGGPAAILAKDSIKEVTCLAFPELGMEAVWKIEVEDFPAFIVVDDKGNDMYSK 565
>ref|YP_001335207.1| fumarase B (fumarate hydratase class I), anaerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
gb|ABR76977.1| fumarase B (fumarate hydratase class I), anaerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
Length = 550
Score = 693 bits (1789), Expect = 0.0, Method: Composition-based stats.
Identities = 334/543 (61%), Positives = 420/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L H DTEY L++K++VSV ++LKVE LTLLA +A D
Sbjct: 2 STKPFVYQDPFP-LAHDDTEYYLLSKEHVSVAEFDG--QQVLKVEPQALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LR SH + SI DPEASDND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 AFMLRVSHQQQVASILLDPEASDNDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL++GV++ YT NLRYSQN PL MY E NTG NLPAQIDLY+ G EY
Sbjct: 119 QRVWTGGGDEAALAQGVYNTYTEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYSVDGEEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK+++ P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCMAKGGGSANKTYLYQETKALITPAKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS +Y D LPT+ +E G +RD+++EQ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 EATLKTVKLASTRYYDGLPTEGNE-HGQAFRDVQLEQELLQEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCPIG+GVSCSADR AKIN+DGIW+EKLE +P KY+PE Q +
Sbjct: 298 IRVIRLPRHGASCPIGMGVSCSADRNIKAKINRDGIWIEKLESNPGKYIPEHLR-QAGEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V I+LN PM +I A+LS HPV TRLSL GTIIVARDIAHA+++E+++N + LP Y+K+
Sbjct: 357 EVVSINLNQPMSEILAQLSAHPVSTRLSLNGTIIVARDIAHAKLKELIDNGEALPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P ASGS GPTTAGRMD +VDL Q++G S VMLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYASGSLGPTTAGRMDSYVDLLQSHGASMVMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKSLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001177280.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Enterobacter sp. 638]
gb|ABP61229.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Enterobacter sp. 638]
Length = 549
Score = 693 bits (1789), Expect = 0.0, Method: Composition-based stats.
Identities = 330/543 (60%), Positives = 424/543 (78%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L H DT+Y L+TK++VSVV EILKVE LTLLA +A D
Sbjct: 2 SNKPFYYQNPFP-LEHDDTDYYLLTKEHVSVVEFAG--QEILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRPSH + +I DP+AS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 AFMLRPSHQKQVAAILHDPDASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE ALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLY+ G EY
Sbjct: 119 QRVWTGGGDEAALSQGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK+++ P L+N+L +K+ ++GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCMAKGGGSANKTYLYQETKALITPAKLKNYLVDKMRSLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS +Y D LPT+ +E G +RD+++EQ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTRYYDGLPTEGNE-HGQAFRDVQLEQELLQEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +PA+Y+PE +Q +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLEHNPAQYIPESLREQ-GEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V I+LN PM++I A+L+ HPV TRLSL GTIIVARD+AHA+++E+++N + LP Y+K+
Sbjct: 357 DVVSINLNSPMNEILAQLTAHPVSTRLSLNGTIIVARDMAHAKLKELIDNGEELPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++G S VMLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGASMVMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SI+ +E + ELGMEA+WKIEVENFPAFI+ DDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIKSLECVAYPELGMEAIWKIEVENFPAFILADDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001005156.1| fumarate hydratase, class I [Yersinia enterocolitica subsp.
enterocolitica 8081]
emb|CAL10918.1| fumarate hydratase, class I [Yersinia enterocolitica subsp.
enterocolitica 8081]
Length = 547
Score = 692 bits (1787), Expect = 0.0, Method: Composition-based stats.
Identities = 332/547 (60%), Positives = 425/547 (77%), Gaps = 13/547 (2%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY LV+ ++VSV ++LKVE LTLLA A D
Sbjct: 2 SNKPFHYQDPFP-LKEDDTEYYLVSNNHVSVAQFEGH--DMLKVEPEALTLLAQHAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G KG
Sbjct: 59 SFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +Y
Sbjct: 119 QRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYQEVNTGTNLPAQIDLYSTEGEDY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F FV KGGGSANK +L+QETK++L+P L+++L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLFVTKGGGSANKTYLYQETKALLSPGKLKDYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD+++EQ +++ +++G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDIQLEQELLEAAQDLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPE----VTEDQ 368
RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE TE +
Sbjct: 298 VRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLRHSTEGK 357
Query: 369 LLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPD 428
+ VKIDLN PM I ELS++PV TRLSLTGTIIV RDIAHA+++E L+N + LP
Sbjct: 358 V-----VKIDLNRPMADILKELSQYPVSTRLSLTGTIIVGRDIAHAKLKERLDNGEGLPQ 412
Query: 429 YIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTE 488
YIK+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+
Sbjct: 413 YIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTD 472
Query: 489 ACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGN 548
AC K+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGN
Sbjct: 473 ACHKHGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGN 532
Query: 549 DFFQQLR 555
DFFQQ++
Sbjct: 533 DFFQQIQ 539
>ref|YP_001402228.1| fumarate hydratase, class I [Yersinia pseudotuberculosis IP 31758]
gb|ABS49480.1| fumarate hydratase, class I [Yersinia pseudotuberculosis IP 31758]
Length = 547
Score = 692 bits (1786), Expect = 0.0, Method: Composition-based stats.
Identities = 336/547 (61%), Positives = 422/547 (77%), Gaps = 13/547 (2%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY LV+ +VSV +ILKVE LTLLA +A D
Sbjct: 2 SNKPFHYQDPFP-LKEDDTEYYLVSDKHVSVAQFEGH--DILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G KG
Sbjct: 59 SFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G EY
Sbjct: 119 QRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGEEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F FV KGGGSANK +L+QETK++L P L+ FL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLFVTKGGGSANKTYLYQETKALLTPGRLKAFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD +EQ +++ +++G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDTALEQELLEAAQDLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPE----VTEDQ 368
RV+R+PRHGASCPIG+GVSCSADR KIN+ GIW+EKLE +P KY+PE TE Q
Sbjct: 298 VRVVRLPRHGASCPIGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLRHSTEGQ 357
Query: 369 LLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPD 428
+ VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP
Sbjct: 358 V-----VKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQ 412
Query: 429 YIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTE 488
YIK+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+
Sbjct: 413 YIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTD 472
Query: 489 ACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGN 548
AC K+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGN
Sbjct: 473 ACHKHGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGN 532
Query: 549 DFFQQLR 555
DFFQQ++
Sbjct: 533 DFFQQIQ 539
>ref|YP_001743642.1| fumarate hydratase [Escherichia coli SMS-3-5]
gb|ACB18046.1| fumarate hydratase [Escherichia coli SMS-3-5]
Length = 548
Score = 692 bits (1786), Expect = 0.0, Method: Composition-based stats.
Identities = 336/546 (61%), Positives = 419/546 (76%), Gaps = 11/546 (2%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +L K
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPE----ELRKA 353
Query: 373 ---PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDY 429
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP Y
Sbjct: 354 GEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQY 413
Query: 430 IKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEA 489
IK+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+A
Sbjct: 414 IKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDA 473
Query: 490 CKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGND 549
CKK+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGND
Sbjct: 474 CKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGND 533
Query: 550 FFQQLR 555
FFQQ++
Sbjct: 534 FFQQIQ 539
>ref|NP_756975.1| Fumarate hydratase class I, anaerobic [Escherichia coli CFT073]
ref|ZP_00723073.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli F11]
ref|YP_543654.1| fumarate hydratase class I, anaerobic [Escherichia coli UTI89]
ref|YP_672209.1| fumarate hydratase class I, anaerobic [Escherichia coli 536]
ref|YP_859731.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
APEC O1]
gb|AAN83549.1|AE016771_60 Fumarate hydratase class I, anaerobic [Escherichia coli CFT073]
gb|ABE10123.1| fumarate hydratase class I, anaerobic [Escherichia coli UTI89]
gb|ABG72308.1| fumarate hydratase class I, anaerobic [Escherichia coli 536]
gb|ABJ03607.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
APEC O1]
Length = 548
Score = 692 bits (1786), Expect = 0.0, Method: Composition-based stats.
Identities = 333/542 (61%), Positives = 418/542 (77%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDIQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+PE Q +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPEELR-QAGEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|NP_707511.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 301]
ref|NP_837298.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 2457T]
gb|AAN43218.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 301]
gb|AAP17105.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 2457T]
Length = 548
Score = 692 bits (1785), Expect = 0.0, Method: Composition-based stats.
Identities = 335/546 (61%), Positives = 419/546 (76%), Gaps = 11/546 (2%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQSPFP-LKKNDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +L K
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPE----ELRKA 353
Query: 373 ---PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDY 429
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP Y
Sbjct: 354 GEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQY 413
Query: 430 IKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEA 489
IK+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+A
Sbjct: 414 IKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDA 473
Query: 490 CKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGND 549
CKK+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGND
Sbjct: 474 CKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGND 533
Query: 550 FFQQLR 555
FFQQ++
Sbjct: 534 FFQQIQ 539
>ref|XP_001696634.1| fumarate hydratase [Chlamydomonas reinhardtii]
gb|EDP08611.1| fumarate hydratase [Chlamydomonas reinhardtii]
Length = 589
Score = 692 bits (1785), Expect = 0.0, Method: Composition-based stats.
Identities = 337/546 (61%), Positives = 418/546 (76%), Gaps = 4/546 (0%)
Query: 8 WFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASR 67
W A + P L + + + +T D+VSV + A ++L+V LTLLA
Sbjct: 45 WLATAAPSPAFVYQELFEMAKANIPWRKLTGDHVSVAD--AAGKKVLQVAPEALTLLADS 102
Query: 68 AIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAII 127
A+ DV H LRP HL L +I +DPEAS NDRFVAL+L+KNANIAA +LPGCQDTGTA I
Sbjct: 103 AMRDVAHLLRPGHLQQLANILKDPEASANDRFVALELLKNANIAAGFVLPGCQDTGTAAI 162
Query: 128 AGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYAT 187
G +G+ V+T+G DEE LSRGV YT+TNLRYSQ PL M+ EKNTG NLPAQI+L+A+
Sbjct: 163 MGKRGQYVWTDGRDEEHLSRGVFRAYTSTNLRYSQVAPLDMFSEKNTGTNLPAQIELFAS 222
Query: 188 KGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVV 247
G Y+F F+AKGGGSANK L+Q+TK++LN KSL FL +KI ++GT+ACPPYH+AVV+
Sbjct: 223 PGSSYDFQFIAKGGGSANKTSLYQQTKALLNEKSLTAFLTDKIKSLGTAACPPYHLAVVI 282
Query: 248 GGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGK 307
GG SAEM +K VK AS +YLD LPT + + G YRDLE E ++DI R +G+GAQFGGK
Sbjct: 283 GGLSAEMNLKTVKLASTRYLDTLPTSGN-ALGRAYRDLEWEGRLLDISRQLGIGAQFGGK 341
Query: 308 YFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTED 367
YF HD RVIR+PRHGASCP+G+GVSCSADRQAL KI +G+++E LE +P +YLP+VT +
Sbjct: 342 YFCHDVRVIRLPRHGASCPVGVGVSCSADRQALGKITGEGVFLEALERNPGQYLPDVTHE 401
Query: 368 QLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLP 427
Q L VK++LN PM ++ A+LS P++TRLSLTGT++VARDIAHA+++E L K LP
Sbjct: 402 Q-LSTDVVKVNLNRPMQEVLAQLSSFPIRTRLSLTGTLVVARDIAHAKLQERLAAGKGLP 460
Query: 428 DYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVT 487
Y K+H +YYAGPAK PE ASGSFGPTTAGRMD +VD F A GGS V LAKGNRS+ VT
Sbjct: 461 QYAKDHIIYYAGPAKTPEGYASGSFGPTTAGRMDSYVDEFMAAGGSLVTLAKGNRSRAVT 520
Query: 488 EACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKG 547
+ACKK+ GFYLGSIGGPAA+LA + I+KVEVL+ ELGMEAVW+IEVE+FPAFIVVDDKG
Sbjct: 521 QACKKHRGFYLGSIGGPAAILAQNCIKKVEVLEYPELGMEAVWRIEVEDFPAFIVVDDKG 580
Query: 548 NDFFQQ 553
NDFFQ+
Sbjct: 581 NDFFQK 586
>ref|NP_406801.1| fumarate hydratase, class I [Yersinia pestis CO92]
ref|NP_668188.1| fumarase A [Yersinia pestis KIM]
ref|NP_991748.1| fumarate hydratase, class I [Yersinia pestis biovar Microtus str.
91001]
ref|YP_069337.1| fumarase A (fumarate hydratase class I), aerobic isozyme [Yersinia
pseudotuberculosis IP 32953]
ref|YP_652716.1| fumarate hydratase, class I [Yersinia pestis Antiqua]
ref|YP_646690.1| fumarate hydratase, class I [Yersinia pestis Nepal516]
ref|YP_001164357.1| fumarate hydratase, class I [Yersinia pestis Pestoides F]
ref|ZP_02022718.1| fumarate hydratase, class I [Yersinia pestis CA88-4125]
ref|YP_001605497.1| fumarate hydratase, class I [Yersinia pestis Angola]
ref|ZP_02221496.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
F1991016]
ref|ZP_02225315.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
IP275]
ref|ZP_02231089.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
E1979001]
ref|ZP_02239036.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
B42003004]
ref|ZP_02305001.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
UG05-0454]
ref|ZP_02313292.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
MG05-1020]
ref|ZP_02315047.1| fumarate hydratase, class I [Yersinia pestis biovar Mediaevalis
str. K1973002]
ref|YP_001871272.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Yersinia pseudotuberculosis PB1/+]
gb|AAM84439.1|AE013688_4 fumarase A [Yersinia pestis KIM]
gb|AAS60625.1| fumarate hydratase, class I [Yersinia pestis biovar Microtus str.
91001]
emb|CAH20036.1| fumarase A (fumarate hydratase class I), aerobic isozyme [Yersinia
pseudotuberculosis IP 32953]
gb|ABG17090.1| fumarase [Yersinia pestis Nepal516]
gb|ABG14771.1| fumarase [Yersinia pestis Antiqua]
emb|CAL21926.1| fumarate hydratase, class I [Yersinia pestis CO92]
gb|ABP41384.1| fumarase [Yersinia pestis Pestoides F]
gb|EDM39335.1| fumarate hydratase, class I [Yersinia pestis CA88-4125]
gb|ABX87267.1| fumarate hydratase, class I [Yersinia pestis Angola]
gb|EDR34007.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
IP275]
gb|EDR39453.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
F1991016]
gb|EDR43399.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
E1979001]
gb|EDR50268.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
B42003004]
gb|EDR56479.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
MG05-1020]
gb|EDR63389.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
UG05-0454]
gb|EDR67210.1| fumarate hydratase, class I [Yersinia pestis biovar Mediaevalis
str. K1973002]
gb|ACC87815.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Yersinia pseudotuberculosis PB1/+]
Length = 547
Score = 691 bits (1784), Expect = 0.0, Method: Composition-based stats.
Identities = 335/547 (61%), Positives = 422/547 (77%), Gaps = 13/547 (2%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY LV+ +VSV +ILKVE LTLLA +A D
Sbjct: 2 SNKPFHYQDPFP-LKEDDTEYYLVSDKHVSVAQFEGH--DILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G KG
Sbjct: 59 SFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G EY
Sbjct: 119 QRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGEEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F FV KGGGSANK +L+QETK++L P L+ FL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLFVTKGGGSANKTYLYQETKALLTPGRLKAFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD +EQ +++ +++G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDTALEQELLEAAQDLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPE----VTEDQ 368
RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE TE Q
Sbjct: 298 VRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLRHSTEGQ 357
Query: 369 LLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPD 428
+ VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP
Sbjct: 358 V-----VKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQ 412
Query: 429 YIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTE 488
YIK+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+
Sbjct: 413 YIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTD 472
Query: 489 ACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGN 548
AC K+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGN
Sbjct: 473 ACHKHGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGN 532
Query: 549 DFFQQLR 555
DFFQQ++
Sbjct: 533 DFFQQIQ 539
>ref|NP_416129.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. MG1655]
ref|NP_753899.1| Fumarate hydratase class I, aerobic [Escherichia coli CFT073]
ref|ZP_00722811.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli F11]
ref|ZP_00926573.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli 101-1]
ref|AP_002233.1| aerobic Class I fumarate hydratase [Escherichia coli W3110]
ref|YP_540809.1| fumarase A [Escherichia coli UTI89]
ref|YP_669464.1| fumarate hydratase class I, aerobic [Escherichia coli 536]
ref|YP_852711.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
APEC O1]
ref|YP_001462901.1| fumarate hydratase [Escherichia coli E24377A]
ref|YP_001730596.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. DH10B]
sp|P0AC33|FUMA_ECOLI Fumarate hydratase class I, aerobic (Fumarase)
sp|P0AC34|FUMA_ECOL6 Fumarate hydratase class I, aerobic (Fumarase)
gb|AAN80464.1|AE016761_39 Fumarate hydratase class I, aerobic [Escherichia coli CFT073]
emb|CAA25204.1| unnamed protein product [Escherichia coli]
dbj|BAA15360.1| aerobic Class I fumarate hydratase [Escherichia coli W3110]
gb|AAC74684.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. MG1655]
gb|ABE07278.1| fumarase A [Escherichia coli UTI89]
gb|ABG69563.1| fumarate hydratase class I, aerobic [Escherichia coli 536]
gb|ABJ00997.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
APEC O1]
gb|ABV17591.1| fumarate hydratase [Escherichia coli E24377A]
gb|ACB02818.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. DH10B]
Length = 548
Score = 691 bits (1784), Expect = 0.0, Method: Composition-based stats.
Identities = 335/546 (61%), Positives = 419/546 (76%), Gaps = 11/546 (2%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +L K
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPE----ELRKA 353
Query: 373 ---PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDY 429
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP Y
Sbjct: 354 GEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQY 413
Query: 430 IKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEA 489
IK+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+A
Sbjct: 414 IKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDA 473
Query: 490 CKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGND 549
CKK+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGND
Sbjct: 474 CKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGND 533
Query: 550 FFQQLR 555
FFQQ++
Sbjct: 534 FFQQIQ 539
>ref|YP_689106.1| Fumarate hydratase class I, aerobic [Shigella flexneri 5 str. 8401]
gb|ABF03801.1| Fumarate hydratase class I, aerobic [Shigella flexneri 5 str. 8401]
Length = 548
Score = 691 bits (1784), Expect = 0.0, Method: Composition-based stats.
Identities = 335/546 (61%), Positives = 419/546 (76%), Gaps = 11/546 (2%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQSPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +L K
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPE----ELRKA 353
Query: 373 ---PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDY 429
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP Y
Sbjct: 354 GEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQY 413
Query: 430 IKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEA 489
IK+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+A
Sbjct: 414 IKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDA 473
Query: 490 CKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGND 549
CKK+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGND
Sbjct: 474 CKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGND 533
Query: 550 FFQQLR 555
FFQQ++
Sbjct: 534 FFQQIQ 539
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|XP_828580.1| fumarate hydratase class I [Trypanosoma br... 907 0.0
ref|YP_689106.1| Fumarate hydratase class I, aerobic [Shige... 887 0.0
ref|NP_416129.1| fumarate hydratase (fumarase A), aerobic C... 887 0.0
ref|YP_310482.1| fumarase A [Shigella sonnei Ss046] >gi|752... 887 0.0
ref|YP_001743642.1| fumarate hydratase [Escherichia coli SM... 886 0.0
ref|ZP_00922444.1| COG1951: Tartrate dehydratase alpha subu... 885 0.0
ref|NP_707511.1| fumarase A, fumarate hydratase Class I; ae... 885 0.0
ref|NP_756975.1| Fumarate hydratase class I, anaerobic [Esc... 884 0.0
ref|ZP_02904384.1| fumarate hydratase class I, anaerobic [E... 884 0.0
ref|NP_288047.1| fumarase A = fumarate hydratase Class I; a... 884 0.0
ref|YP_403430.1| fumarase A [Shigella dysenteriae Sd197] >g... 884 0.0
ref|ZP_02646500.1| hypothetical protein Senterenterica_1279... 883 0.0
ref|YP_001746516.1| fumarate hydratase class I, anaerobic [... 882 0.0
ref|YP_313027.1| fumarase B [Shigella sonnei Ss046] >gi|752... 882 0.0
ref|YP_410570.1| fumarase B [Shigella boydii Sb227] >gi|812... 882 0.0
ref|YP_001726834.1| hydro-lyase, Fe-S type, tartrate/fumara... 881 0.0
ref|ZP_00925876.1| COG1951: Tartrate dehydratase alpha subu... 881 0.0
ref|ZP_00722640.1| COG1951: Tartrate dehydratase alpha subu... 881 0.0
ref|NP_313131.1| fumarase B [Escherichia coli O157:H7 str. ... 881 0.0
ref|NP_418546.1| anaerobic class I fumarate hydratase (fuma... 881 0.0
gb|EEH92879.1| fumarate hydratase class I [Citrobacter sp. ... 880 0.0
ref|ZP_02739706.1| fumarase B [Escherichia coli O157:H7 str... 880 0.0
gb|AAA23827.1| anaerobic class I fumarase (EC 4.2.1.2) 879 0.0
gb|AAA97022.1| fumarase [Escherichia coli] 878 0.0
ref|YP_691399.1| Fumarate hydratase class I, anaerobic [Shi... 878 0.0
ref|NP_290755.1| fumarase B= fumarate hydratase Class I; an... 878 0.0
ref|NP_709819.1| fumarase B, fumarate hydratase Class I [Sh... 878 0.0
ref|ZP_03836673.1| fumarate hydratase class I, aerobic [Cit... 877 0.0
ref|YP_001177280.1| hydro-lyase, Fe-S type, tartrate/fumara... 875 0.0
ref|NP_406801.1| fumarate hydratase, class I [Yersinia pest... 875 0.0
ref|YP_001455261.1| hypothetical protein CKO_03749 [Citroba... 875 0.0
ref|XP_804521.1| fumarate hydratase, putative [Trypanosoma ... 875 0.0
ref|XP_817100.1| fumarate hydratase, putative [Trypanosoma ... 875 0.0
ref|YP_001453190.1| hypothetical protein CKO_01623 [Citroba... 875 0.0
ref|YP_001722124.1| hydro-lyase, Fe-S type, tartrate/fumara... 874 0.0
ref|YP_001402228.1| fumarate hydratase, class I [Yersinia p... 874 0.0
ref|YP_001438056.1| hypothetical protein ESA_01967 [Enterob... 873 0.0
ref|YP_001176561.1| hydro-lyase, Fe-S type, tartrate/fumara... 873 0.0
ref|YP_001335207.1| fumarase B (fumarate hydratase class I)... 872 0.0
ref|YP_001480245.1| hydro-lyase, Fe-S type, tartrate/fumara... 872 0.0
ref|YP_001335177.1| fumarase A (fumarate hydratase class I)... 872 0.0
ref|ZP_00822736.1| COG1951: Tartrate dehydratase alpha subu... 871 0.0
ref|YP_001005156.1| fumarate hydratase, class I [Yersinia e... 871 0.0
ref|ZP_02561418.1| fumarase B [Salmonella enterica subsp. e... 871 0.0
ref|ZP_00831475.1| COG1951: Tartrate dehydratase alpha subu... 870 0.0
ref|YP_001929009.1| fumarate hydratase class I anaerobic [P... 870 0.0
ref|ZP_02685331.1| fumarase B [Salmonella enterica subsp. e... 869 0.0
ref|ZP_00825174.1| COG1951: Tartrate dehydratase alpha subu... 869 0.0
ref|NP_905572.1| fumarate hydratase class I, anaerobic [Por... 869 0.0
ref|ZP_00835117.1| COG1951: Tartrate dehydratase alpha subu... 868 0.0
ref|ZP_03833166.1| fumarate hydratase class I, aerobic [Pec... 868 0.0
ref|YP_049013.1| fumarate hydratase class I, aerobic [Erwin... 868 0.0
ref|ZP_03828861.1| fumarate hydratase class I, aerobic [Pec... 868 0.0
ref|NP_463165.1| fumarase B [Salmonella typhimurium LT2] >g... 868 0.0
ref|ZP_02903194.1| fumarate hydratase [Escherichia albertii... 868 0.0
ref|NP_460429.1| fumarase A [Salmonella typhimurium LT2] >g... 868 0.0
ref|ZP_02665916.1| Fumarate hydratase class I, aerobic [Sal... 867 0.0
ref|ZP_02345313.1| hypothetical protein Sentente_13804 [Sal... 867 0.0
ref|YP_001588077.1| hypothetical protein SPAB_01851 [Salmon... 867 0.0
ref|YP_216472.1| fumarase A (fumarate hydratase class I), a... 867 0.0
ref|ZP_02564600.1| hypothetical protein Senten_02232 [Salmo... 866 0.0
ref|YP_150641.1| Fumarate hydratase class I, aerobic [Salmo... 865 0.0
ref|ZP_02649455.1| hypothetical protein Sententeric_00485 [... 865 0.0
ref|ZP_02351328.1| hypothetical protein Sententeri_15956 [S... 865 0.0
ref|NP_456064.1| Fumarate hydratase class I, aerobic [Salmo... 864 0.0
ref|ZP_02559788.1| Fumarate hydratase class I, aerobic [Sal... 863 0.0
ref|ZP_02338828.1| hypothetical protein Sentent_08256 [Salm... 862 0.0
ref|YP_001570548.1| hypothetical protein SARI_01510 [Salmon... 860 0.0
gb|EEJ97739.1| fumarase [Thermomonospora curvata DSM 43183] 858 0.0
ref|ZP_03838974.1| hypothetical protein CATC2_23480 [Citrob... 856 0.0
ref|YP_001591410.1| hypothetical protein SPAB_05302 [Salmon... 855 0.0
ref|ZP_02668652.1| hypothetical protein Senterienterica_188... 855 0.0
gb|EEH96136.1| conserved hypothetical protein [Citrobacter ... 855 0.0
ref|YP_001572321.1| hypothetical protein SARI_03347 [Salmon... 855 0.0
ref|NP_458599.1| fumarate hydratase class I [Salmonella ent... 855 0.0
ref|YP_153174.1| fumarate hydratase class I [Salmonella ent... 854 0.0
ref|ZP_02700852.1| fumarate hydratase class I [Salmonella e... 854 0.0
ref|YP_219166.1| fumarase B (fumarate hydratase class I), a... 853 0.0
ref|ZP_02346001.1| fumarate hydratase class I [Salmonella e... 853 0.0
ref|ZP_02565856.1| fumarate hydratase class I [Salmonella e... 853 0.0
ref|ZP_02349309.1| fumarate hydratase class I [Salmonella e... 853 0.0
ref|NP_824394.1| fumarate hydratase class I [Streptomyces a... 851 0.0
ref|YP_631365.1| fumarate hydratase, class I [Myxococcus xa... 850 0.0
ref|NP_629196.1| fumarate hydratase class I [Streptomyces c... 849 0.0
ref|YP_001299156.1| anaerobic fumarate hydratase class I [B... 848 0.0
ref|YP_097958.1| anaerobic fumarate hydratase class I [Bact... 848 0.0
ref|ZP_02437159.1| hypothetical protein BACSTE_03432 [Bacte... 847 0.0
ref|ZP_02072327.1| hypothetical protein BACUNI_03773 [Bacte... 847 0.0
ref|NP_811169.1| fumarate hydratase class I, anaerobic [Bac... 845 0.0
ref|ZP_01961337.1| hypothetical protein BACCAC_02968 [Bacte... 845 0.0
ref|ZP_02066092.1| hypothetical protein BACOVA_03087 [Bacte... 845 0.0
ref|XP_782370.2| PREDICTED: similar to SJCHGC09380 protein ... 844 0.0
ref|YP_001823993.1| putative fumarate hydratase class I [St... 843 0.0
gb|ACO63163.1| putative fumarate hydratase class1-malate <=... 843 0.0
ref|ZP_03878233.1| fumarase [Haliangium ochraceum DSM 14365... 842 0.0
ref|XP_001745789.1| predicted protein [Monosiga brevicollis... 842 0.0
ref|YP_001907860.1| Fumarase A [Erwinia tasmaniensis] >gi|1... 842 0.0
ref|ZP_02030648.1| hypothetical protein PARMER_00620 [Parab... 842 0.0
ref|ZP_03859476.1| fumarase [Kribbella flavida DSM 17836] >... 842 0.0
emb|CAM74591.1| Tartrate dehydratase alpha subunit/Fumarate... 840 0.0
ref|XP_001683549.1| fumarate hydratase, putative [Leishmani... 840 0.0
ref|NP_539933.1| FUMARATE HYDRATASE CLASS I, AEROBIC [Bruce... 840 0.0
ref|NP_697971.1| fumarate hydratase, class I [Brucella suis... 839 0.0
ref|ZP_02187346.1| Fumarate hydratase class I aerobic [alph... 838 0.0
ref|YP_001241352.1| fumarase A (fumarate hydratase class I)... 838 0.0
ref|YP_001627633.1| hydro-lyase, Fe-S type, tartrate/fumara... 838 0.0
ref|YP_001258929.1| fumarate hydratase, class I [Brucella o... 838 0.0
ref|ZP_01547699.1| Fumarate lyase [Stappia aggregata IAM 12... 838 0.0
ref|YP_001878733.1| hydro-lyase, Fe-S type, tartrate/fumara... 838 0.0
ref|XP_001565298.1| fumarate hydratase, putative [Leishmani... 837 0.0
gb|AAW26769.1| SJCHGC09380 protein [Schistosoma japonicum] 837 0.0
ref|YP_119417.1| putative fumarate hydratase [Nocardia farc... 837 0.0
ref|YP_001304100.1| fumarate hydratase class I, anaerobic [... 837 0.0
ref|ZP_02753357.1| fumarase A [Escherichia coli O157:H7 str... 836 0.0
ref|YP_846452.1| hydro-lyases, Fe-S type, tartrate/fumarate... 836 0.0
ref|YP_001592802.1| hydro-lyase, Fe-S type, tartrate/fumara... 836 0.0
ref|YP_531414.1| hydro-lyases, Fe-S type, tartrate/fumarate... 836 0.0
ref|YP_420694.1| Fumarate hydratase class I aerobic [Magnet... 836 0.0
ref|NP_949213.1| fumarate hydratase, class I [Rhodopseudomo... 835 0.0
ref|YP_001370770.1| hydro-lyase, Fe-S type, tartrate/fumara... 833 0.0
ref|YP_385514.1| Fe-S type hydro-lyase tartrate/fumarate al... 833 0.0
ref|ZP_01774525.1| hydro-lyase, Fe-S type, tartrate/fumarat... 832 0.0
gb|EEJ99437.1| fumarase [Tsukamurella paurometabola DSM 20162] 832 0.0
ref|XP_001696634.1| fumarate hydratase [Chlamydomonas reinh... 832 0.0
ref|YP_745628.1| fumarate hydratase [Granulibacter bethesde... 831 0.0
ref|ZP_02302798.1| hydro-lyase, Fe-S type, tartrate/fumarat... 831 0.0
ref|ZP_02013449.1| hydro-lyase, Fe-S type, tartrate/fumarat... 831 0.0
ref|YP_001206931.1| fumarase A (fumarate hydratase class I)... 831 0.0
ref|YP_568845.1| hydro-lyases, Fe-S type, tartrate/fumarate... 831 0.0
ref|YP_487367.1| Fumarate hydratase, class I [Rhodopseudomo... 830 0.0
ref|YP_001234467.1| hydro-lyase, Fe-S type, tartrate/fumara... 830 0.0
ref|YP_780500.1| hydro-lyases, Fe-S type, tartrate/fumarate... 828 0.0
ref|YP_001610994.1| hypothetical protein sce0357 [Sorangium... 827 0.0
ref|NP_772436.1| Fumarate hydratase class I [Bradyrhizobium... 827 0.0
ref|ZP_02166775.1| Fumarate lyase:Fe-S type hydro-lyase tar... 826 0.0
ref|ZP_02858786.1| hydro-lyase, Fe-S type, tartrate/fumarat... 826 0.0
ref|ZP_02297379.1| hydro-lyase, Fe-S type, tartrate/fumarat... 826 0.0
ref|YP_768288.1| utative fumarate hydratase class I, aerobi... 825 0.0
ref|ZP_03925560.1| fumarate hydratase class I [Actinomyces ... 824 0.0
ref|YP_465275.1| fumarase [Anaeromyxobacter dehalogenans 2C... 822 0.0
ref|YP_705834.1| fumarate hydratase class I [Rhodococcus sp... 821 0.0
gb|EDT29778.1| fumarate hydratase class I, anaerobic (Fumar... 821 0.0
ref|YP_001380232.1| hydro-lyase, Fe-S type, tartrate/fumara... 821 0.0
ref|NP_952048.1| fumarate hydratase, class I [Geobacter sul... 819 0.0
ref|ZP_03815532.1| fumarase [Actinosynnema mirum DSM 43827]... 818 0.0
ref|ZP_03922648.1| fumarate hydratase class I [Mobiluncus c... 818 0.0
ref|YP_002767658.1| fumarate hydratase class I [Rhodococcus... 818 0.0
ref|ZP_00831149.1| COG1951: Tartrate dehydratase alpha subu... 817 0.0
ref|YP_001817521.1| hydro-lyase, Fe-S type, tartrate/fumara... 817 0.0
ref|ZP_02132117.1| hydro-lyase, Fe-S type, tartrate/fumarat... 816 0.0
ref|ZP_00993841.1| fumarate hydratase class I [Janibacter s... 815 0.0
ref|ZP_02981625.1| hydro-lyase, Fe-S type, tartrate/fumarat... 815 0.0
ref|ZP_02174352.1| hydro-lyase, Fe-S type, tartrate/fumarat... 815 0.0
ref|ZP_00832031.1| COG1951: Tartrate dehydratase alpha subu... 815 0.0
ref|YP_001601151.1| Fumarate hydratase class [Gluconacetoba... 813 0.0
ref|ZP_02323626.1| hydro-lyase, Fe-S type, tartrate/fumarat... 812 0.0
ref|YP_900437.1| hydro-lyases, Fe-S type, tartrate/fumarate... 812 0.0
ref|YP_001104025.1| fumarate hydratase class I [Saccharopol... 812 0.0
ref|ZP_01312990.1| hydro-lyases, Fe-S type, tartrate/fumara... 811 0.0
ref|YP_922266.1| hydro-lyases, Fe-S type, tartrate/fumarate... 811 0.0
ref|YP_001008178.1| fumarate hydratase class I, anaerobic [... 811 0.0
ref|YP_001840478.1| Fumarate hydratase class I, aerobic (Fu... 809 0.0
ref|XP_001417167.1| predicted protein [Ostreococcus lucimar... 808 0.0
ref|ZP_02959159.1| hypothetical protein PROSTU_00957 [Provi... 808 0.0
ref|XP_814517.1| fumarate hydratase, putative [Trypanosoma ... 807 0.0
ref|YP_001230419.1| hydro-lyase, Fe-S type, tartrate/fumara... 807 0.0
ref|YP_002783153.1| fumarate hydratase class I [Rhodococcus... 804 0.0
ref|XP_821204.1| fumarate hydratase, putative [Trypanosoma ... 804 0.0
ref|ZP_02424765.1| hypothetical protein ALIPUT_00893 [Alist... 803 0.0
ref|YP_001833973.1| hydro-lyase, Fe-S type, tartrate/fumara... 802 0.0
ref|YP_427293.1| tartrate dehydrogenase [Rhodospirillum rub... 801 0.0
ref|XP_001566537.1| fumarate hydratase, putative [Leishmani... 801 0.0
ref|XP_001466723.1| fumarate hydratase [Leishmania infantum... 800 0.0
gb|ABF20401.1| fumarate hydratase [Leishmania infantum] 799 0.0
gb|ABF20376.1| fumarate hydratase [Leishmania infantum] 799 0.0
gb|ABF20395.1| fumarate hydratase [Leishmania infantum] 799 0.0
ref|YP_679867.1| fumarate hydratase, class I [Cytophaga hut... 798 0.0
gb|ABF20402.1| fumarate hydratase [Leishmania tropica] 798 0.0
ref|XP_847862.1| fumarate hydratase, putative [Leishmania m... 798 0.0
ref|YP_867134.1| hydro-lyases, Fe-S type, tartrate/fumarate... 798 0.0
ref|ZP_01909505.1| fumarate hydratase, class I [Plesiocysti... 797 0.0
gb|ABF20398.1| fumarate hydratase [Leishmania donovani arch... 796 0.0
ref|XP_844042.1| fumarate hydratase, putative [Trypanosoma ... 795 0.0
ref|YP_001161051.1| hydro-lyase, Fe-S type, tartrate/fumara... 794 0.0
gb|ABF20388.1| fumarate hydratase [Leishmania infantum] 793 0.0
ref|YP_001453977.1| hypothetical protein CKO_02424 [Citroba... 792 0.0
gb|EEH92162.1| conserved hypothetical protein [Citrobacter ... 791 0.0
ref|YP_001539419.1| hydro-lyase, Fe-S type, tartrate/fumara... 790 0.0
ref|NP_968997.1| fumarate hydratase, class I [Bdellovibrio ... 790 0.0
ref|YP_001193234.1| hydro-lyase, Fe-S type, tartrate/fumara... 788 0.0
ref|ZP_03835909.1| hypothetical protein CATC2_07906 [Citrob... 788 0.0
ref|YP_001742833.1| hydro-lyase, Fe-S type, tartrate/fumara... 786 0.0
emb|CAL51520.1| fumarate hydratase class I (ISS) [Ostreococ... 784 0.0
ref|ZP_03850894.1| fumarate hydratase [Chryseobacterium gle... 784 0.0
ref|NP_286449.1| putative fumarate hydratase [Escherichia c... 782 0.0
ref|YP_469892.1| fumarate hydratase class I protein [Rhizob... 779 0.0
ref|YP_001571219.1| hypothetical protein SARI_02205 [Salmon... 779 0.0
ref|ZP_01733811.1| fumarate hydratase, class I [Flavobacter... 776 0.0
ref|ZP_01876100.1| fumarate hydratase, class I [Lentisphaer... 766 0.0
ref|XP_001734600.1| fumarate hydratase class I, anaerobic, ... 759 0.0
ref|YP_001528580.1| hydro-lyase, Fe-S type, tartrate/fumara... 754 0.0
ref|ZP_00380865.1| COG1951: Tartrate dehydratase alpha subu... 751 0.0
ref|YP_887304.1| fumarate hydratase class I, anaerobic [Myc... 734 0.0
ref|XP_763097.1| fumarate hydratase [Theileria parva strain... 729 0.0
ref|XP_001608904.1| fumarate hydratase, putative [Babesia b... 722 0.0
ref|XP_954791.1| Fumarate hydratase class I, putative [Thei... 722 0.0
ref|ZP_00417946.1| Fe-S type hydro-lyases tartrate/fumarate... 709 0.0
ref|YP_002800960.1| fumarate hydratase, class I [Azotobacte... 707 0.0
ref|YP_350180.1| Fe-S type hydro-lyase tartrate/fumarate al... 704 0.0
ref|YP_261882.1| fumarate hydratase, class I, putative [Pse... 703 0.0
ref|YP_237099.1| Fe-S type hydro-lyase tartrate/fumarate al... 702 0.0
ref|YP_001188750.1| hydro-lyase, Fe-S type, tartrate/fumara... 701 0.0
ref|NP_794095.1| fumarate hydratase, class I, putative [Pse... 700 0.0
ref|YP_001171684.1| probable fumarase [Pseudomonas stutzeri... 699 0.0
ref|YP_001350238.1| fumarate hydratase, class I [Pseudomona... 699 0.0
ref|YP_001670678.1| hydro-lyase, Fe-S type, tartrate/fumara... 698 0.0
ref|YP_276169.1| fumarate hydratase, class I, putative [Pse... 697 0.0
ref|YP_606854.1| fumarate hydratase, class I [Pseudomonas e... 697 0.0
ref|YP_001747874.1| hydro-lyase, Fe-S type, tartrate/fumara... 697 0.0
ref|NP_253023.1| probable fumarase [Pseudomonas aeruginosa ... 696 0.0
ref|ZP_01364002.1| hypothetical protein PaerPA_01001105 [Ps... 696 0.0
ref|YP_959303.1| hydro-lyases, Fe-S type, tartrate/fumarate... 696 0.0
ref|XP_745408.1| fumarate hydratase [Plasmodium chabaudi ch... 695 0.0
ref|NP_743058.1| fumarate hydratase, class I [Pseudomonas p... 695 0.0
ref|YP_130595.1| Putative fumarate hydratase, class I [Phot... 695 0.0
ref|YP_001579270.1| hydro-lyase, Fe-S type, tartrate/fumara... 694 0.0
ref|ZP_01235291.1| Putative fumarate hydratase, class I [Vi... 694 0.0
ref|YP_001266281.1| hydro-lyase, Fe-S type, tartrate/fumara... 693 0.0
ref|ZP_02885805.1| hydro-lyase, Fe-S type, tartrate/fumarat... 693 0.0
ref|ZP_01221083.1| Putative fumarate hydratase, class I [Ph... 693 0.0
ref|YP_001341191.1| hydro-lyase, Fe-S type, tartrate/fumara... 692 0.0
ref|ZP_01892241.1| Tartrate dehydratase alpha subunit/Fumar... 692 0.0
ref|ZP_01077265.1| probable fumarase [Marinomonas sp. MED12... 692 0.0
ref|YP_001858166.1| hydro-lyase, Fe-S type, tartrate/fumara... 691 0.0
ref|ZP_01737188.1| Tartrate dehydratase alpha subunit/Fumar... 691 0.0
ref|YP_856949.1| fumarate hydratase, class I [Aeromonas hyd... 691 0.0
ref|YP_001674474.1| hydro-lyase, Fe-S type, tartrate/fumara... 690 0.0
ref|YP_436102.1| Tartrate dehydratase alpha subunit/Fumarat... 690 0.0
ref|ZP_01043530.1| Fumarase B [Idiomarina baltica OS145] >g... 690 0.0
ref|ZP_02000730.1| fumarate hydratase, class I, anaerobic [... 690 0.0
ref|ZP_00986943.1| COG1951: Tartrate dehydratase alpha subu... 690 0.0
ref|YP_001501893.1| hydro-lyase, Fe-S type, tartrate/fumara... 689 0.0
ref|YP_001120114.1| hydro-lyases, Fe-S type, tartrate/fumar... 688 0.0
ref|ZP_01162226.1| Putative fumarate hydratase, class I [Ph... 688 0.0
ref|YP_440213.1| hydro-lyase, Fe-S type, tartrate/fumarate ... 688 0.0
ref|NP_798252.1| fumarate hydratase, class I [Vibrio paraha... 688 0.0
ref|YP_156087.1| Fumarase B [Idiomarina loihiensis L2TR] >g... 688 0.0
ref|YP_296439.1| Fe-S type hydro-lyase tartrate/fumarate al... 687 0.0
ref|YP_106350.1| hydro-lyase, Fe-S type, tartrate/fumarate ... 687 0.0
gb|EEH57583.1| predicted protein [Micromonas pusilla CCMP1545] 687 0.0
ref|ZP_02365109.1| hydro-lyases, Fe-S type, tartrate/fumara... 687 0.0
ref|ZP_01330957.1| hypothetical protein BpseS_03000801 [Bur... 687 0.0
ref|YP_001904287.1| fumarate hydratase [Xanthomonas campest... 687 0.0
ref|ZP_00980069.1| COG1951: Tartrate dehydratase alpha subu... 687 0.0
ref|YP_001142090.1| fumarate hydratase, class I [Aeromonas ... 687 0.0
ref|ZP_02894165.1| hydro-lyase, Fe-S type, tartrate/fumarat... 686 0.0
ref|YP_726983.1| fumarate hydratase class I [Ralstonia eutr... 686 0.0
ref|YP_001899668.1| hydro-lyase, Fe-S type, tartrate/fumara... 686 0.0
ref|ZP_02911362.1| hydro-lyase, Fe-S type, tartrate/fumarat... 686 0.0
ref|ZP_02465678.1| hydro-lyase, Fe-S type, tartrate/fumarat... 686 0.0
ref|ZP_01953547.1| fumarate hydratase, class I, putative [V... 686 0.0
ref|ZP_02405688.1| fumarate hydratase, class I [Burkholderi... 686 0.0
ref|YP_001895052.1| hydro-lyase, Fe-S type, tartrate/fumara... 686 0.0
ref|NP_636789.1| fumarate hydratase [Xanthomonas campestris... 686 0.0
ref|YP_369761.1| Fe-S type hydro-lyase tartrate/fumarate [B... 686 0.0
ref|YP_774123.1| hydro-lyases, Fe-S type, tartrate/fumarate... 686 0.0
ref|ZP_02357979.1| hydro-lyases, Fe-S type, tartrate/fumara... 686 0.0
ref|NP_230949.1| fumarate hydratase, class I, putative [Vib... 685 0.0
ref|YP_625721.1| hydro-lyases, Fe-S type, tartrate/fumarate... 685 0.0
ref|YP_110392.1| fumarate hydratase [Burkholderia pseudomal... 685 0.0
ref|YP_001808807.1| hydro-lyase, Fe-S type, tartrate/fumara... 685 0.0
ref|ZP_02381373.1| hydro-lyases, Fe-S type, tartrate/fumara... 685 0.0
ref|ZP_01484995.1| hypothetical protein VchoV5_02002396 [Vi... 685 0.0
ref|YP_001765502.1| hydro-lyase, Fe-S type, tartrate/fumara... 685 0.0
ref|YP_001094029.1| hydro-lyases, Fe-S type, tartrate/fumar... 685 0.0
ref|ZP_02008711.1| hydro-lyase, Fe-S type, tartrate/fumarat... 684 0.0
ref|YP_584421.1| hydro-lyases, Fe-S type, tartrate/fumarate... 684 0.0
ref|ZP_02492649.1| fumarate hydratase [Burkholderia pseudom... 684 0.0
ref|YP_557895.1| tartrate/fumarate Fe-S type hydro-lyases [... 684 0.0
ref|YP_001629387.1| Fumarate hydratase class I anaerobic [B... 683 0.0
gb|ABA55852.1| hypothetical protein [Vibrio sp. DAT722] 683 0.0
emb|CAM32536.1| Fumarate hydratase protein [Herbaspirillum ... 683 0.0
ref|NP_520076.1| PROBABLE FUMARATE HYDRATASE PROTEIN [Ralst... 683 0.0
ref|ZP_01984559.1| fumarate hydratase, class I [Vibrio harv... 682 0.0
ref|ZP_01869058.1| fumarate hydratase, class I [Vibrio shil... 682 0.0
ref|YP_001445107.1| fumarate hydratase, class I [Vibrio har... 682 0.0
ref|ZP_01116436.1| Tartrate dehydratase alpha subunit/Fumar... 681 0.0
ref|ZP_01104763.1| fumarate hydratase, class I, anaerobic [... 681 0.0
ref|YP_001352570.1| fumarate hydratase, class I [Janthinoba... 680 0.0
ref|ZP_00991791.1| fumarate hydratase, class I [Vibrio sple... 680 0.0
ref|ZP_01064590.1| fumarate hydratase, class I [Vibrio sp. ... 680 0.0
ref|NP_761117.1| Fumarate hydratase [Vibrio vulnificus CMCP... 680 0.0
ref|NP_934872.1| fumarate hydratase, class I [Vibrio vulnif... 680 0.0
ref|YP_562918.1| hydro-lyases, Fe-S type, tartrate/fumarate... 680 0.0
ref|YP_001020579.1| putative fumarate hydratase [Methylibiu... 680 0.0
ref|YP_001099230.1| fumarase A (fumarate hydratase class I)... 680 0.0
ref|ZP_01112233.1| fumarate hydratase, class I [Alteromonas... 680 0.0
ref|YP_693260.1| fumarate hydratase, putative [Alcanivorax ... 680 0.0
ref|NP_885804.1| putative fumarate hydratase [Bordetella pa... 679 0.0
ref|ZP_02194608.1| fumarate hydratase, class I [Vibrio camp... 679 0.0
Sequences not found previously or not previously below threshold:
>ref|XP_828580.1| fumarate hydratase class I [Trypanosoma brucei TREU927]
gb|EAN79468.1| fumarate hydratase class I, putative [Trypanosoma brucei]
Length = 555
Score = 907 bits (2345), Expect = 0.0, Method: Composition-based stats.
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAG 60
MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAG
Sbjct: 1 MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAG 60
Query: 61 LTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQ 120
LTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQ
Sbjct: 61 LTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQ 120
Query: 121 DTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPA 180
DTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPA
Sbjct: 121 DTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPA 180
Query: 181 QIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPP 240
QIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPP
Sbjct: 181 QIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPP 240
Query: 241 YHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGM 300
YHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGM
Sbjct: 241 YHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGM 300
Query: 301 GAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKY 360
GAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKY
Sbjct: 301 GAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKY 360
Query: 361 LPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREML 420
LPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREML
Sbjct: 361 LPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREML 420
Query: 421 ENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
ENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG
Sbjct: 421 ENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
Query: 481 NRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAF 540
NRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAF
Sbjct: 481 NRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAF 540
Query: 541 IVVDDKGNDFFQQLR 555
IVVDDKGNDFFQQLR
Sbjct: 541 IVVDDKGNDFFQQLR 555
>ref|YP_689106.1| Fumarate hydratase class I, aerobic [Shigella flexneri 5 str. 8401]
gb|ABF03801.1| Fumarate hydratase class I, aerobic [Shigella flexneri 5 str. 8401]
Length = 548
Score = 887 bits (2293), Expect = 0.0, Method: Composition-based stats.
Identities = 333/543 (61%), Positives = 417/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQSPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK+
Sbjct: 357 EAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|NP_416129.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. MG1655]
ref|NP_753899.1| Fumarate hydratase class I, aerobic [Escherichia coli CFT073]
ref|ZP_00722811.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli F11]
ref|ZP_00926573.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli 101-1]
ref|AP_002233.1| aerobic Class I fumarate hydratase [Escherichia coli W3110]
ref|YP_540809.1| fumarase A [Escherichia coli UTI89]
ref|YP_669464.1| fumarate hydratase class I, aerobic [Escherichia coli 536]
ref|YP_852711.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
APEC O1]
ref|YP_001462901.1| fumarate hydratase [Escherichia coli E24377A]
ref|YP_001730596.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. DH10B]
sp|P0AC33|FUMA_ECOLI Fumarate hydratase class I, aerobic (Fumarase)
sp|P0AC34|FUMA_ECOL6 Fumarate hydratase class I, aerobic (Fumarase)
gb|AAN80464.1|AE016761_39 Fumarate hydratase class I, aerobic [Escherichia coli CFT073]
emb|CAA25204.1| unnamed protein product [Escherichia coli]
dbj|BAA15360.1| aerobic Class I fumarate hydratase [Escherichia coli W3110]
gb|AAC74684.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. MG1655]
gb|ABE07278.1| fumarase A [Escherichia coli UTI89]
gb|ABG69563.1| fumarate hydratase class I, aerobic [Escherichia coli 536]
gb|ABJ00997.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
APEC O1]
gb|ABV17591.1| fumarate hydratase [Escherichia coli E24377A]
gb|ACB02818.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. DH10B]
Length = 548
Score = 887 bits (2292), Expect = 0.0, Method: Composition-based stats.
Identities = 333/543 (61%), Positives = 417/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK+
Sbjct: 357 EAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_310482.1| fumarase A [Shigella sonnei Ss046]
ref|ZP_00712947.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli B171]
ref|ZP_00717388.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli B7A]
ref|ZP_00719204.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli E110019]
ref|ZP_00728591.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli E22]
ref|YP_407968.1| fumarase A [Shigella boydii Sb227]
ref|YP_001458391.1| fumarate hydratase [Escherichia coli HS]
ref|YP_001724989.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Escherichia coli ATCC 8739]
ref|YP_001880366.1| fumarate hydratase [Shigella boydii CDC 3083-94]
ref|ZP_02999252.1| fumarate hydratase class I, aerobic [Escherichia coli 53638]
gb|AAZ88247.1| fumarase A [Shigella sonnei Ss046]
gb|ABB66140.1| fumarase A [Shigella boydii Sb227]
gb|ABV06008.1| fumarate hydratase [Escherichia coli HS]
gb|ACA77662.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Escherichia coli ATCC 8739]
gb|ACD09923.1| fumarate hydratase [Shigella boydii CDC 3083-94]
gb|EDU62284.1| fumarate hydratase class I, aerobic [Escherichia coli 53638]
Length = 548
Score = 887 bits (2292), Expect = 0.0, Method: Composition-based stats.
Identities = 333/543 (61%), Positives = 417/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGCDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK+
Sbjct: 357 EAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001743642.1| fumarate hydratase [Escherichia coli SMS-3-5]
gb|ACB18046.1| fumarate hydratase [Escherichia coli SMS-3-5]
Length = 548
Score = 886 bits (2290), Expect = 0.0, Method: Composition-based stats.
Identities = 334/543 (61%), Positives = 417/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK+
Sbjct: 357 EAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|ZP_00922444.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Shigella dysenteriae 1012]
Length = 548
Score = 885 bits (2289), Expect = 0.0, Method: Composition-based stats.
Identities = 333/543 (61%), Positives = 417/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQGFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK+
Sbjct: 357 EAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|NP_707511.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 301]
ref|NP_837298.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 2457T]
gb|AAN43218.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 301]
gb|AAP17105.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 2457T]
Length = 548
Score = 885 bits (2288), Expect = 0.0, Method: Composition-based stats.
Identities = 333/543 (61%), Positives = 417/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQSPFP-LKKNDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK+
Sbjct: 357 EAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|NP_756975.1| Fumarate hydratase class I, anaerobic [Escherichia coli CFT073]
ref|ZP_00723073.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli F11]
ref|YP_543654.1| fumarate hydratase class I, anaerobic [Escherichia coli UTI89]
ref|YP_672209.1| fumarate hydratase class I, anaerobic [Escherichia coli 536]
ref|YP_859731.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
APEC O1]
gb|AAN83549.1|AE016771_60 Fumarate hydratase class I, anaerobic [Escherichia coli CFT073]
gb|ABE10123.1| fumarate hydratase class I, anaerobic [Escherichia coli UTI89]
gb|ABG72308.1| fumarate hydratase class I, anaerobic [Escherichia coli 536]
gb|ABJ03607.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
APEC O1]
Length = 548
Score = 884 bits (2286), Expect = 0.0, Method: Composition-based stats.
Identities = 332/542 (61%), Positives = 417/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDIQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPEELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|ZP_02904384.1| fumarate hydratase class I, anaerobic [Escherichia albertii
TW07627]
gb|EDS90156.1| fumarate hydratase class I, anaerobic [Escherichia albertii
TW07627]
Length = 548
Score = 884 bits (2286), Expect = 0.0, Method: Composition-based stats.
Identities = 330/542 (60%), Positives = 414/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVAEFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + SI DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVASILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L++FL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKDFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y D LPT+ +E G +RD+++EQ ++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDNLPTEGNE-HGQAFRDVQLEQELLKEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPEELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++P+ TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPISTRLSLTGTIIVGRDIAHAKLKELIDEGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPTGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|NP_288047.1| fumarase A = fumarate hydratase Class I; aerobic isozyme
[Escherichia coli O157:H7 EDL933]
ref|NP_310345.1| fumarase A [Escherichia coli O157:H7 str. Sakai]
ref|ZP_02742709.1| fumarase A [Escherichia coli O157:H7 str. EC4045]
ref|ZP_02771017.1| fumarase A [Escherichia coli O157:H7 str. EC4115]
ref|ZP_02775598.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4113]
ref|ZP_02782481.1| fumarase A [Escherichia coli O157:H7 str. EC4401]
ref|ZP_02788693.1| fumarase A [Escherichia coli O157:H7 str. EC4501]
ref|ZP_02796159.1| fumarase A [Escherichia coli O157:H7 str. EC4486]
ref|ZP_02800847.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4196]
ref|ZP_02808440.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4076]
ref|ZP_02814454.1| fumarase A [Escherichia coli O157:H7 str. EC869]
ref|ZP_02820502.1| fumarase A [Escherichia coli O157:H7 str. EC4042]
ref|ZP_02825877.1| fumarase A [Escherichia coli O157:H7 str. EC508]
sp|Q8X4P8|FUMA_ECO57 Fumarate hydratase class I, aerobic (Fumarase)
gb|AAG56599.1|AE005384_9 fumarase A = fumarate hydratase Class I; aerobic isozyme
[Escherichia coli O157:H7 EDL933]
dbj|BAB35741.1| fumarase A [Escherichia coli O157:H7 str. Sakai]
gb|EDU32558.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4196]
gb|EDU53361.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4113]
gb|EDU68187.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4076]
Length = 548
Score = 884 bits (2285), Expect = 0.0, Method: Composition-based stats.
Identities = 332/543 (61%), Positives = 417/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VS+ EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQAPFP-LKKDDTEYYLLTSEHVSLSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK+
Sbjct: 357 EAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQALGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_403430.1| fumarase A [Shigella dysenteriae Sd197]
gb|ABB61939.1| fumarase A [Shigella dysenteriae Sd197]
Length = 548
Score = 884 bits (2285), Expect = 0.0, Method: Composition-based stats.
Identities = 332/543 (61%), Positives = 416/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QE K++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQEAKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK+
Sbjct: 357 EAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|ZP_02646500.1| hypothetical protein Senterenterica_12797 [Salmonella enterica
subsp. enterica serovar Agona str. SL483]
Length = 548
Score = 883 bits (2283), Expect = 0.0, Method: Composition-based stats.
Identities = 326/543 (60%), Positives = 415/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 2 SNKPFFYQDPFP-LKKDDTEYYLLTSEHVSVAEFEG--QEILKVAPEALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DP+AS+ND++VALQ ++N++IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPQASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN L MY E NTG NLPAQIDLY+ G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L +K+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVDKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY D LPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 EANLKTVKLASAKYYDALPTEGNE-HGQAFRDIELEKELLFEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLERNPGKYIPEALRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I +LS++PV TRLSL GTIIV RDIAHA+++E ++ + LP YIK+
Sbjct: 357 EAVRVDLNRPMSEILQQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDRGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD Q+ GGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQSQGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+++E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKRLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001746516.1| fumarate hydratase class I, anaerobic [Escherichia coli SMS-3-5]
gb|ACB17618.1| fumarate hydratase class I, anaerobic [Escherichia coli SMS-3-5]
Length = 548
Score = 882 bits (2281), Expect = 0.0, Method: Composition-based stats.
Identities = 331/542 (61%), Positives = 417/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F V+KGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVSKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDIQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPEELRKAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|YP_313027.1| fumarase B [Shigella sonnei Ss046]
ref|ZP_00712106.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli B171]
ref|ZP_00717687.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli B7A]
ref|ZP_00730409.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli E22]
ref|YP_405623.1| fumarase B [Shigella dysenteriae Sd197]
ref|YP_001465621.1| fumarate hydratase [Escherichia coli E24377A]
ref|YP_001460906.1| fumarate hydratase [Escherichia coli HS]
ref|ZP_03002676.1| fumarate hydratase class I, anaerobic [Escherichia coli 53638]
gb|AAZ90792.1| fumarase B [Shigella sonnei Ss046]
gb|ABB64132.1| fumarase B [Shigella dysenteriae Sd197]
gb|ABV08523.1| fumarate hydratase [Escherichia coli HS]
gb|ABV19946.1| fumarate hydratase [Escherichia coli E24377A]
gb|EDU65708.1| fumarate hydratase class I, anaerobic [Escherichia coli 53638]
Length = 548
Score = 882 bits (2281), Expect = 0.0, Method: Composition-based stats.
Identities = 330/542 (60%), Positives = 416/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|YP_410570.1| fumarase B [Shigella boydii Sb227]
gb|ABB68742.1| fumarase B [Shigella boydii Sb227]
Length = 548
Score = 882 bits (2279), Expect = 0.0, Method: Composition-based stats.
Identities = 329/542 (60%), Positives = 415/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTG AII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGIAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|YP_001726834.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Escherichia coli ATCC 8739]
gb|ACA79507.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Escherichia coli ATCC 8739]
Length = 548
Score = 881 bits (2278), Expect = 0.0, Method: Composition-based stats.
Identities = 330/542 (60%), Positives = 415/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 RFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|ZP_00925876.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli 101-1]
Length = 548
Score = 881 bits (2278), Expect = 0.0, Method: Composition-based stats.
Identities = 330/542 (60%), Positives = 416/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPDQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|ZP_00722640.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli E110019]
Length = 548
Score = 881 bits (2278), Expect = 0.0, Method: Composition-based stats.
Identities = 329/542 (60%), Positives = 415/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGND FQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDLFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|NP_313131.1| fumarase B [Escherichia coli O157:H7 str. Sakai]
ref|ZP_02785990.1| fumarase B [Escherichia coli O157:H7 str. EC4501]
dbj|BAB38527.1| fumarase B [Escherichia coli O157:H7 str. Sakai]
Length = 548
Score = 881 bits (2277), Expect = 0.0, Method: Composition-based stats.
Identities = 329/542 (60%), Positives = 414/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSV 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEKAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE P +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHHPGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|NP_418546.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
str. K-12 substr. MG1655]
ref|AP_004623.1| anaerobic class I fumarate hydratase [Escherichia coli W3110]
ref|YP_001732892.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
str. K-12 substr. DH10B]
sp|P14407|FUMB_ECOLI Fumarate hydratase class I, anaerobic (Fumarase)
gb|AAC77083.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
str. K-12 substr. MG1655]
dbj|BAE78124.1| anaerobic class I fumarate hydratase [Escherichia coli W3110]
gb|ACB05114.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
str. K-12 substr. DH10B]
Length = 548
Score = 881 bits (2277), Expect = 0.0, Method: Composition-based stats.
Identities = 329/542 (60%), Positives = 415/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEE LS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEETLSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>gb|EEH92879.1| fumarate hydratase class I [Citrobacter sp. 30_2]
Length = 548
Score = 880 bits (2275), Expect = 0.0, Method: Composition-based stats.
Identities = 331/543 (60%), Positives = 417/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T DYVSV EI+KV LTLLA +A D
Sbjct: 2 SNKPFHYQHPFP-LKKDDTEYYLLTSDYVSVAEFEG--QEIVKVAPQALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEAL+RGV++ Y NLRYSQN L MY E NTG NLPAQIDLY G EY
Sbjct: 119 QRVWTGGGDEEALARGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYTVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+++L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKDYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 EATLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P K++PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGKFIPEELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E L+N + LP Y+K+
Sbjct: 357 EAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERLDNGESLPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAAGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF+
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFK 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|ZP_02739706.1| fumarase B [Escherichia coli O157:H7 str. EC4045]
ref|ZP_02751886.1| fumarase B [Escherichia coli O157:H7 str. EC4206]
ref|ZP_02769460.1| fumarase B [Escherichia coli O157:H7 str. EC4115]
ref|ZP_02773043.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4113]
ref|ZP_02780311.1| fumarase B [Escherichia coli O157:H7 str. EC4401]
ref|ZP_02791400.1| fumarase B [Escherichia coli O157:H7 str. EC4486]
ref|ZP_02799499.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4196]
ref|ZP_02805553.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4076]
ref|ZP_02809758.1| fumarase B [Escherichia coli O157:H7 str. EC869]
ref|ZP_02819581.1| fumarase B [Escherichia coli O157:H7 str. EC4042]
ref|ZP_02823212.1| fumarase B [Escherichia coli O157:H7 str. EC508]
gb|EDU33813.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4196]
gb|EDU55522.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4113]
gb|EDU70784.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4076]
Length = 548
Score = 880 bits (2275), Expect = 0.0, Method: Composition-based stats.
Identities = 329/542 (60%), Positives = 414/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSV 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE P +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHHPGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>gb|AAA23827.1| anaerobic class I fumarase (EC 4.2.1.2)
Length = 548
Score = 879 bits (2273), Expect = 0.0, Method: Composition-based stats.
Identities = 328/542 (60%), Positives = 415/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTL+A +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLVAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEE LS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEETLSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>gb|AAA97022.1| fumarase [Escherichia coli]
Length = 548
Score = 878 bits (2271), Expect = 0.0, Method: Composition-based stats.
Identities = 328/542 (60%), Positives = 414/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTL A +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLXAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEE LS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEETLSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|YP_691399.1| Fumarate hydratase class I, anaerobic [Shigella flexneri 5 str.
8401]
gb|ABF06094.1| Fumarate hydratase class I, anaerobic [Shigella flexneri 5 str.
8401]
Length = 548
Score = 878 bits (2270), Expect = 0.0, Method: Composition-based stats.
Identities = 329/542 (60%), Positives = 415/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE + +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNLGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|NP_290755.1| fumarase B= fumarate hydratase Class I; anaerobic isozyme
[Escherichia coli O157:H7 EDL933]
gb|AAG59321.1|AE005645_7 fumarase B= fumarate hydratase Class I; anaerobic isozyme
[Escherichia coli O157:H7 EDL933]
Length = 548
Score = 878 bits (2269), Expect = 0.0, Method: Composition-based stats.
Identities = 328/542 (60%), Positives = 413/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSV 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEKAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++ IW+EKLE P +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREXIWIEKLEHHPGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|NP_709819.1| fumarase B, fumarate hydratase Class I [Shigella flexneri 2a str.
301]
ref|NP_838862.1| fumarase B, fumarate hydratase Class I [Shigella flexneri 2a str.
2457T]
gb|AAN45526.1| fumarase B, fumarate hydratase Class I [Shigella flexneri 2a str.
301]
gb|AAP18673.1| fumarase B, fumarate hydratase Class I [Shigella flexneri 2a str.
2457T]
Length = 548
Score = 878 bits (2269), Expect = 0.0, Method: Composition-based stats.
Identities = 329/542 (60%), Positives = 415/542 (76%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 2 SNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ENNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE + +Y+P+ +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNLGQYIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK+
Sbjct: 357 EAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|ZP_03836673.1| fumarate hydratase class I, aerobic [Citrobacter youngae ATCC
29220]
Length = 548
Score = 877 bits (2268), Expect = 0.0, Method: Composition-based stats.
Identities = 330/543 (60%), Positives = 417/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T DYVSV E++KV LTLLA +A D
Sbjct: 2 SNKPFHYQHPFP-LKKDDTEYYLLTSDYVSVAEFEG--QEVIKVAPQALTLLARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN L MY E NTG NLPAQIDLY+ G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L+P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLSPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 EATLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR A IN++GIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAMINREGIWIEKLEHNPGKYIPEELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E L++ + LP YIK+
Sbjct: 357 EAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERLDSGENLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAAGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF+
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFK 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001177280.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Enterobacter sp. 638]
gb|ABP61229.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Enterobacter sp. 638]
Length = 549
Score = 875 bits (2263), Expect = 0.0, Method: Composition-based stats.
Identities = 330/543 (60%), Positives = 424/543 (78%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L H DT+Y L+TK++VSVV EILKVE LTLLA +A D
Sbjct: 2 SNKPFYYQNPFP-LEHDDTDYYLLTKEHVSVVEFAG--QEILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRPSH + +I DP+AS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 AFMLRPSHQKQVAAILHDPDASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE ALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLY+ G EY
Sbjct: 119 QRVWTGGGDEAALSQGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK+++ P L+N+L +K+ ++GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCMAKGGGSANKTYLYQETKALITPAKLKNYLVDKMRSLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS +Y D LPT+ +E G +RD+++EQ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTRYYDGLPTEGNE-HGQAFRDVQLEQELLQEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +PA+Y+PE +Q +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLEHNPAQYIPESLREQG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V I+LN PM++I A+L+ HPV TRLSL GTIIVARD+AHA+++E+++N + LP Y+K+
Sbjct: 357 DVVSINLNSPMNEILAQLTAHPVSTRLSLNGTIIVARDMAHAKLKELIDNGEELPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++G S VMLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGASMVMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SI+ +E + ELGMEA+WKIEVENFPAFI+ DDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIKSLECVAYPELGMEAIWKIEVENFPAFILADDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|NP_406801.1| fumarate hydratase, class I [Yersinia pestis CO92]
ref|NP_668188.1| fumarase A [Yersinia pestis KIM]
ref|NP_991748.1| fumarate hydratase, class I [Yersinia pestis biovar Microtus str.
91001]
ref|YP_069337.1| fumarase A (fumarate hydratase class I), aerobic isozyme [Yersinia
pseudotuberculosis IP 32953]
ref|YP_652716.1| fumarate hydratase, class I [Yersinia pestis Antiqua]
ref|YP_646690.1| fumarate hydratase, class I [Yersinia pestis Nepal516]
ref|YP_001164357.1| fumarate hydratase, class I [Yersinia pestis Pestoides F]
ref|ZP_02022718.1| fumarate hydratase, class I [Yersinia pestis CA88-4125]
ref|YP_001605497.1| fumarate hydratase, class I [Yersinia pestis Angola]
ref|ZP_02221496.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
F1991016]
ref|ZP_02225315.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
IP275]
ref|ZP_02231089.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
E1979001]
ref|ZP_02239036.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
B42003004]
ref|ZP_02305001.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
UG05-0454]
ref|ZP_02313292.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
MG05-1020]
ref|ZP_02315047.1| fumarate hydratase, class I [Yersinia pestis biovar Mediaevalis
str. K1973002]
ref|YP_001871272.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Yersinia pseudotuberculosis PB1/+]
gb|AAM84439.1|AE013688_4 fumarase A [Yersinia pestis KIM]
gb|AAS60625.1| fumarate hydratase, class I [Yersinia pestis biovar Microtus str.
91001]
emb|CAH20036.1| fumarase A (fumarate hydratase class I), aerobic isozyme [Yersinia
pseudotuberculosis IP 32953]
gb|ABG17090.1| fumarase [Yersinia pestis Nepal516]
gb|ABG14771.1| fumarase [Yersinia pestis Antiqua]
emb|CAL21926.1| fumarate hydratase, class I [Yersinia pestis CO92]
gb|ABP41384.1| fumarase [Yersinia pestis Pestoides F]
gb|EDM39335.1| fumarate hydratase, class I [Yersinia pestis CA88-4125]
gb|ABX87267.1| fumarate hydratase, class I [Yersinia pestis Angola]
gb|EDR34007.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
IP275]
gb|EDR39453.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
F1991016]
gb|EDR43399.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
E1979001]
gb|EDR50268.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
B42003004]
gb|EDR56479.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
MG05-1020]
gb|EDR63389.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
UG05-0454]
gb|EDR67210.1| fumarate hydratase, class I [Yersinia pestis biovar Mediaevalis
str. K1973002]
gb|ACC87815.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Yersinia pseudotuberculosis PB1/+]
Length = 547
Score = 875 bits (2263), Expect = 0.0, Method: Composition-based stats.
Identities = 332/543 (61%), Positives = 419/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY LV+ +VSV +ILKVE LTLLA +A D
Sbjct: 2 SNKPFHYQDPFP-LKEDDTEYYLVSDKHVSVAQFEGH--DILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G KG
Sbjct: 59 SFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G EY
Sbjct: 119 QRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGEEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F FV KGGGSANK +L+QETK++L P L+ FL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLFVTKGGGSANKTYLYQETKALLTPGRLKAFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD +EQ +++ +++G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDTALEQELLEAAQDLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 VRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-HSTEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK+
Sbjct: 357 QVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001455261.1| hypothetical protein CKO_03749 [Citrobacter koseri ATCC BAA-895]
gb|ABV14825.1| hypothetical protein CKO_03749 [Citrobacter koseri ATCC BAA-895]
Length = 548
Score = 875 bits (2262), Expect = 0.0, Method: Composition-based stats.
Identities = 329/542 (60%), Positives = 411/542 (75%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S F + P + TEY L+T D+VSV ILKVE LTLLA +A D
Sbjct: 2 SNKEFIYQAPFP-MGEDKTEYYLLTSDHVSVGEFEG--ESILKVEPQALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP H + SI DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPEHQQQVASILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE ALS+GV + Y NLRYSQN L MY E NTG NLPAQIDLY G EY
Sbjct: 119 QRVWTGGGDEAALSKGVFNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYTVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS Y D LPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASAHYYDGLPTEGNE-HGQAFRDIQLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +PA+Y+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPAQYIPESLRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSL+GTIIV RDIAHA+++E +E+ + LP YIK+
Sbjct: 357 EVVKVDLNRPMKEILAQLSQYPVSTRLSLSGTIIVGRDIAHAKLKERIESGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
YGGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 YGGFYLGSIGGPAAVLAQQSIKHLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|XP_804521.1| fumarate hydratase, putative [Trypanosoma cruzi strain CL Brener]
gb|EAN82670.1| fumarate hydratase, putative [Trypanosoma cruzi]
Length = 555
Score = 875 bits (2262), Expect = 0.0, Method: Composition-based stats.
Identities = 469/555 (84%), Positives = 507/555 (91%)
Query: 1 MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAG 60
MLRRS+ K+ PFK+VPL+PH+ H DT + L+TKDYVSVV PG GLPEIL+V+ G
Sbjct: 1 MLRRSAAALGKKAPVPFKYVPLIPHVSHDDTPFRLLTKDYVSVVRPGCGLPEILQVDVEG 60
Query: 61 LTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQ 120
L LAS A GDVQH LRPSHLASLR IF+DPEASDNDRFVALQL+KNANIAAAR+LPGCQ
Sbjct: 61 LAKLASEAFGDVQHLLRPSHLASLRRIFDDPEASDNDRFVALQLLKNANIAAARVLPGCQ 120
Query: 121 DTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPA 180
DTGTAI+AGYKGEQVFTNGD+ EALSRGV+ IYTTTNLRYSQNVPLTM+DEKNTG NLPA
Sbjct: 121 DTGTAIVAGYKGEQVFTNGDECEALSRGVYKIYTTTNLRYSQNVPLTMFDEKNTGSNLPA 180
Query: 181 QIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPP 240
QIDLYATKG EY F FVAKGGGSANKA+LFQETKSVLNPKSLR FLEEKI IGT+ACPP
Sbjct: 181 QIDLYATKGQEYNFMFVAKGGGSANKAYLFQETKSVLNPKSLRKFLEEKIGAIGTAACPP 240
Query: 241 YHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGM 300
YHMAVVVGGTSAEMT+K VKYASCKY D LPTKPDESKGY YRD EME +VMDIC N+GM
Sbjct: 241 YHMAVVVGGTSAEMTLKTVKYASCKYYDNLPTKPDESKGYAYRDTEMENVVMDICYNMGM 300
Query: 301 GAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKY 360
GAQFGGKYFAHDARVIR+PRHGASCPIGIGVSCSADRQALAKINKDGIW+E+LE DPAKY
Sbjct: 301 GAQFGGKYFAHDARVIRLPRHGASCPIGIGVSCSADRQALAKINKDGIWLEQLETDPAKY 360
Query: 361 LPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREML 420
LPE+TEDQLLK PPV IDL+MPM+KIRAELS++PVKTRLSL+GTIIVARD+AHARMREML
Sbjct: 361 LPEITEDQLLKTPPVNIDLSMPMEKIRAELSKYPVKTRLSLSGTIIVARDMAHARMREML 420
Query: 421 ENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
E KPLP+YIKNHPVYYAGPAK PE + SGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG
Sbjct: 421 EAGKPLPEYIKNHPVYYAGPAKCPEGMPSGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
Query: 481 NRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAF 540
NRS+ VT+ACKK+GGFYLGSIGGPAALLA DSIRKVEVLDM ELGMEAVWKIEVENFPAF
Sbjct: 481 NRSRAVTQACKKHGGFYLGSIGGPAALLAKDSIRKVEVLDMAELGMEAVWKIEVENFPAF 540
Query: 541 IVVDDKGNDFFQQLR 555
IV+DDKGNDFFQQL+
Sbjct: 541 IVLDDKGNDFFQQLK 555
>ref|XP_817100.1| fumarate hydratase, putative [Trypanosoma cruzi strain CL Brener]
gb|EAN95249.1| fumarate hydratase, putative [Trypanosoma cruzi]
Length = 555
Score = 875 bits (2262), Expect = 0.0, Method: Composition-based stats.
Identities = 469/555 (84%), Positives = 507/555 (91%)
Query: 1 MLRRSSLWFAPKSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAG 60
MLRRS+ K+ PFK+VPL+PH+ H DT L+TKDYVSVV PG G+PEIL+V+ G
Sbjct: 1 MLRRSAAALGKKAPVPFKYVPLIPHVSHDDTPLRLLTKDYVSVVRPGCGVPEILQVDVEG 60
Query: 61 LTLLASRAIGDVQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQ 120
LT LAS A GDVQH LRPSHLASLR IF+DPEASDNDRFVALQL+KNANIAAAR+LPGCQ
Sbjct: 61 LTRLASEAFGDVQHLLRPSHLASLRKIFDDPEASDNDRFVALQLLKNANIAAARVLPGCQ 120
Query: 121 DTGTAIIAGYKGEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPA 180
DTGTAI+AGYKGEQVFTNGD+ EALSRGV+ IYTTTNLRYSQNVPLTM+DEKNTG NLPA
Sbjct: 121 DTGTAIVAGYKGEQVFTNGDECEALSRGVYKIYTTTNLRYSQNVPLTMFDEKNTGSNLPA 180
Query: 181 QIDLYATKGCEYEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPP 240
QIDLYATKG EY F FVAKGGGSANKA+LFQETKSVLNPKSLR FLEEKI IGT+ACPP
Sbjct: 181 QIDLYATKGQEYNFMFVAKGGGSANKAYLFQETKSVLNPKSLRKFLEEKIGAIGTAACPP 240
Query: 241 YHMAVVVGGTSAEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGM 300
YHMAVVVGGTSAEMT+K VKYASCKY D LPTKPDESKGY YRD EME +VMDIC N+GM
Sbjct: 241 YHMAVVVGGTSAEMTLKTVKYASCKYYDNLPTKPDESKGYAYRDTEMENVVMDICYNMGM 300
Query: 301 GAQFGGKYFAHDARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKY 360
GAQFGGKYFAHDARVIR+PRHGASCPIGIGVSCSADRQALAKINKDGIW+E+LE DPAKY
Sbjct: 301 GAQFGGKYFAHDARVIRLPRHGASCPIGIGVSCSADRQALAKINKDGIWLEQLETDPAKY 360
Query: 361 LPEVTEDQLLKVPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREML 420
LPE+TEDQLLK PPV IDL+MPM+KIRAELS++PVKTRLSL+GTIIVARD+AHARMREML
Sbjct: 361 LPEITEDQLLKTPPVNIDLSMPMEKIRAELSKYPVKTRLSLSGTIIVARDMAHARMREML 420
Query: 421 ENNKPLPDYIKNHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
E KPLP+YIKNHPVYYAGPAK PE + SGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG
Sbjct: 421 EAGKPLPEYIKNHPVYYAGPAKCPEGMPSGSFGPTTAGRMDPFVDLFQANGGSFVMLAKG 480
Query: 481 NRSKRVTEACKKYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAF 540
NRS+ VT+ACKK+GGFYLGSIGGPAALLA DSIRKVEVLDM ELGMEAVWKIEVENFPAF
Sbjct: 481 NRSRAVTQACKKHGGFYLGSIGGPAALLAKDSIRKVEVLDMAELGMEAVWKIEVENFPAF 540
Query: 541 IVVDDKGNDFFQQLR 555
IV+DDKGNDFFQQL+
Sbjct: 541 IVLDDKGNDFFQQLK 555
>ref|YP_001453190.1| hypothetical protein CKO_01623 [Citrobacter koseri ATCC BAA-895]
gb|ABV12755.1| hypothetical protein CKO_01623 [Citrobacter koseri ATCC BAA-895]
Length = 548
Score = 875 bits (2261), Expect = 0.0, Method: Composition-based stats.
Identities = 326/543 (60%), Positives = 414/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+T ++VSV E+LKV LTL+A +A D
Sbjct: 2 SNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVAEFEG--QEVLKVAPEALTLMARQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DP+AS+ND++VALQ ++N++IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILRDPDASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLY+ G EY
Sbjct: 119 QRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYSVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+N+L +K+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVDKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 EATLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLTEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRKGIWIEKLEHNPGKYIPEELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM I +LS++PV TRLSL GTIIV RDIAHA+++E ++ + LP Y+K+
Sbjct: 357 EAVRVDLNQPMKAILQQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDRGEGLPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD Q+ GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQSQGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SIR +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIRSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001722124.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Yersinia pseudotuberculosis YPIII]
gb|ACA69671.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Yersinia pseudotuberculosis YPIII]
Length = 547
Score = 874 bits (2260), Expect = 0.0, Method: Composition-based stats.
Identities = 331/543 (60%), Positives = 419/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY LV+ +VSV +ILKVE LTLLA +A D
Sbjct: 2 SNKPFHYQDPFP-LKEDDTEYYLVSDKHVSVAQFEGH--DILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G KG
Sbjct: 59 SFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G EY
Sbjct: 119 QRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGEEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F FV KGGGSANK +L+QETK++L P L+ FL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLFVTKGGGSANKTYLYQETKALLTPGRLKAFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD +EQ +++ +++G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDTALEQELLEAAQDLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 VRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-HSTEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK+
Sbjct: 357 QVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKI+VE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIDVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001402228.1| fumarate hydratase, class I [Yersinia pseudotuberculosis IP 31758]
gb|ABS49480.1| fumarate hydratase, class I [Yersinia pseudotuberculosis IP 31758]
Length = 547
Score = 874 bits (2259), Expect = 0.0, Method: Composition-based stats.
Identities = 333/543 (61%), Positives = 419/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY LV+ +VSV +ILKVE LTLLA +A D
Sbjct: 2 SNKPFHYQDPFP-LKEDDTEYYLVSDKHVSVAQFEGH--DILKVEPEALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G KG
Sbjct: 59 SFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G EY
Sbjct: 119 QRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGEEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F FV KGGGSANK +L+QETK++L P L+ FL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLFVTKGGGSANKTYLYQETKALLTPGRLKAFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD +EQ +++ +++G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDTALEQELLEAAQDLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RV+R+PRHGASCPIG+GVSCSADR KIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 VRVVRLPRHGASCPIGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-HSTEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK+
Sbjct: 357 QVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001438056.1| hypothetical protein ESA_01967 [Enterobacter sakazakii ATCC
BAA-894]
gb|ABU77220.1| hypothetical protein ESA_01967 [Enterobacter sakazakii ATCC
BAA-894]
Length = 548
Score = 873 bits (2258), Expect = 0.0, Method: Composition-based stats.
Identities = 335/543 (61%), Positives = 420/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L +TEY L+T+D+VSV EILKVE LTLLA A D
Sbjct: 2 SGKPFFWQEPFP-LKKDETEYYLLTRDHVSVSEFEG--QEILKVEPQALTLLARHAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N+ IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILSDPEASENDKYVALQFLRNSEIAAKGILPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL++GV+ YT NLRYSQN L MY E NTG NLPAQIDLY+ G EY
Sbjct: 119 QRVWTGGGDEAALAQGVYQTYTQDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L P L+ +L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLTPGKLKAYLVEKMRTLGTAACPPYHVAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD+++E+ ++ RN+G+GAQFGGKYFAHD
Sbjct: 239 EATLKTVKLASTKYYDGLPTEGNE-HGQAFRDVQLEEELLQEARNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLESNPGKYIPEALRRAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V++DLN PM +I A+LS++PV TRLSL+GTIIVARDIAHA+++E +++ LP Y+K+
Sbjct: 357 EAVRVDLNRPMSEILAQLSQYPVSTRLSLSGTIIVARDIAHAKLKERIDSGAGLPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL QANGGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQANGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SIR +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIRHLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001176561.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Enterobacter sp. 638]
gb|ABP60510.1| fumarase [Enterobacter sp. 638]
Length = 548
Score = 873 bits (2256), Expect = 0.0, Method: Composition-based stats.
Identities = 330/543 (60%), Positives = 416/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L TEY L+T+D+VSV EILKVE LTLLA +A D
Sbjct: 2 SNKPFHYQNPFP-LSQDQTEYYLLTRDHVSVSEFEG--QEILKVEPQALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I D +AS+ND++VALQ ++N++IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILSDLQASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIITGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL+ GV++ Y NLRYSQN L MY E NTG NLPAQIDLY+ G EY
Sbjct: 119 QRVWTGGGDEAALAHGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L+P L+N+L EK+ ++GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLSPGKLKNYLVEKMRSLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD+++EQ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDIQLEQELLVEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +P KY+PE +
Sbjct: 298 VRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLEKNPGKYIPEALRKAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V +DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E LEN + LP Y+K+
Sbjct: 357 EAVHVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLQERLENGEGLPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VD QANGGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQANGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF+
Sbjct: 477 HGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFK 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001335207.1| fumarase B (fumarate hydratase class I), anaerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
gb|ABR76977.1| fumarase B (fumarate hydratase class I), anaerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
Length = 550
Score = 872 bits (2255), Expect = 0.0, Method: Composition-based stats.
Identities = 333/543 (61%), Positives = 419/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L H DTEY L++K++VSV ++LKVE LTLLA +A D
Sbjct: 2 STKPFVYQDPFP-LAHDDTEYYLLSKEHVSVAEFDG--QQVLKVEPQALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LR SH + SI DPEASDND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 AFMLRVSHQQQVASILLDPEASDNDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL++GV++ YT NLRYSQN PL MY E NTG NLPAQIDLY+ G EY
Sbjct: 119 QRVWTGGGDEAALAQGVYNTYTEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYSVDGEEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK+++ P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCMAKGGGSANKTYLYQETKALITPAKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS +Y D LPT+ +E G +RD+++EQ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 EATLKTVKLASTRYYDGLPTEGNE-HGQAFRDVQLEQELLQEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCPIG+GVSCSADR AKIN+DGIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPIGMGVSCSADRNIKAKINRDGIWIEKLESNPGKYIPEHLRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
V I+LN PM +I A+LS HPV TRLSL GTIIVARDIAHA+++E+++N + LP Y+K+
Sbjct: 357 EVVSINLNQPMSEILAQLSAHPVSTRLSLNGTIIVARDIAHAKLKELIDNGEALPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P ASGS GPTTAGRMD +VDL Q++G S VMLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPAGYASGSLGPTTAGRMDSYVDLLQSHGASMVMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKSLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001480245.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Serratia proteamaculans 568]
gb|ABV43117.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Serratia proteamaculans 568]
Length = 548
Score = 872 bits (2253), Expect = 0.0, Method: Composition-based stats.
Identities = 322/543 (59%), Positives = 415/543 (76%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L+++D+VSV E+LKV LTLLA A D
Sbjct: 2 SNKPFHYQDPFP-LKKDDTEYYLLSRDHVSVSEFEG--QEVLKVAPEALTLLAQHAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I +DP+AS+ND++VALQ ++N+ IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILKDPDASENDKYVALQFLRNSEIAAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE ALSRGV++ + NLRYSQN L MY+E NTG NLPAQIDLY+ G EY
Sbjct: 119 QRVWTGGGDEAALSRGVYNTFIEDNLRYSQNAALDMYNEVNTGSNLPAQIDLYSVDGEEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++L+P L+++L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALLSPGKLKDYLVEKMRTLGTAACPPYHVAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD+ +E+ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 EATLKTVKLASTKYYDGLPTEGNE-HGQAFRDVALEEELLKEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RV+R+PRHGASCP+G+GVSCSADR KIN+DGIW+EKLE +P K++P+ +
Sbjct: 298 IRVVRLPRHGASCPVGMGVSCSADRNIKGKINRDGIWLEKLEHNPGKFIPQELRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VKIDLN PM I +LS+ PV TRLSL+GTIIV RDIAHA+++E L+N + LP Y+K+
Sbjct: 357 EAVKIDLNRPMADILKQLSQFPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P+ ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPDGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ + ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKSLTCVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
+++
Sbjct: 537 KIQ 539
>ref|YP_001335177.1| fumarase A (fumarate hydratase class I), aerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
gb|ABR76947.1| fumarase A (fumarate hydratase class I), aerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
Length = 548
Score = 872 bits (2253), Expect = 0.0, Method: Composition-based stats.
Identities = 332/543 (61%), Positives = 421/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY L++ DYVSV E+LKV+ LTLLA A D
Sbjct: 2 SNKPFVYQDPFP-LKKDDTEYYLLSSDYVSVAEFAG--QEVLKVDPQALTLLAQHAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + I DPEAS+ND++VALQ ++N++IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPAHQQQVADILNDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE AL++GV++ Y NLRYSQN PL MY E NTG NLPAQIDLYAT G EY
Sbjct: 119 QRVWTGGGDEAALAQGVYNTYIQDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYATDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK+++ P L+N+L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCIAKGGGSANKTYLYQETKALITPAKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD++MEQ ++ +N+G+GAQFGGKYFAHD
Sbjct: 239 EATLKTVKLASTKYYDGLPTEGNE-HGQAFRDVQMEQELLLEAQNLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +P KY+PE +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLESNPGKYIPEHLRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK++LN PM +I A+LS++PV TRLSL+GTIIVARDIAHA+++E+++N + LP Y+K+
Sbjct: 357 EAVKVNLNQPMSEILAQLSQYPVSTRLSLSGTIIVARDIAHAKLKELIDNGEALPQYVKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P+ ASGS GPTTAGRMD +VDL Q++G S +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPDGYASGSLGPTTAGRMDSYVDLLQSHGASKIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKSLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|ZP_00822736.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Yersinia bercovieri ATCC
43970]
Length = 547
Score = 871 bits (2252), Expect = 0.0, Method: Composition-based stats.
Identities = 330/543 (60%), Positives = 421/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY LV+ ++VSV ++LKVE LTLLA A D
Sbjct: 2 SNKPFHYQDPFP-LTEDDTEYYLVSNNHVSVAQFEGH--DMLKVEPEALTLLAQHAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G KG
Sbjct: 59 SFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +Y
Sbjct: 119 QRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGEDY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F FV KGGGSANK +L+QETK++L+P L+ +L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLFVTKGGGSANKTYLYQETKALLSPGKLKEYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD+ +EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDIALEQELLEAAQELGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE Q +
Sbjct: 298 VRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-QSNEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK+
Sbjct: 357 KVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEDLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001005156.1| fumarate hydratase, class I [Yersinia enterocolitica subsp.
enterocolitica 8081]
emb|CAL10918.1| fumarate hydratase, class I [Yersinia enterocolitica subsp.
enterocolitica 8081]
Length = 547
Score = 871 bits (2252), Expect = 0.0, Method: Composition-based stats.
Identities = 330/543 (60%), Positives = 422/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY LV+ ++VSV ++LKVE LTLLA A D
Sbjct: 2 SNKPFHYQDPFP-LKEDDTEYYLVSNNHVSVAQFEGH--DMLKVEPEALTLLAQHAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G KG
Sbjct: 59 SFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +Y
Sbjct: 119 QRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYQEVNTGTNLPAQIDLYSTEGEDY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F FV KGGGSANK +L+QETK++L+P L+++L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLFVTKGGGSANKTYLYQETKALLSPGKLKDYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD+++EQ +++ +++G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDIQLEQELLEAAQDLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 VRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-HSTEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VKIDLN PM I ELS++PV TRLSLTGTIIV RDIAHA+++E L+N + LP YIK+
Sbjct: 357 KVVKIDLNRPMADILKELSQYPVSTRLSLTGTIIVGRDIAHAKLKERLDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|ZP_02561418.1| fumarase B [Salmonella enterica subsp. enterica serovar Kentucky
str. CVM29188]
ref|ZP_02656375.1| fumarase B [Salmonella enterica subsp. enterica serovar Kentucky
str. CDC 191]
Length = 548
Score = 871 bits (2251), Expect = 0.0, Method: Composition-based stats.
Identities = 331/542 (61%), Positives = 408/542 (75%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S F + P + TEY L+T DYVSV IL VE LTLLA +A D
Sbjct: 2 SKKEFIYQAPFP-MGEDKTEYYLLTSDYVSVSEFNG--ESILNVEPQALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP H + +I DPEAS+ND++VALQ ++N+ IAA ILP CQDTGTAII G KG
Sbjct: 59 SFMLRPEHQQQVAAILHDPEASENDKYVALQFLRNSEIAAKGILPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE ALS+GV + Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALSKGVFNTYIEDNLRYSQNAPLDMYKEVNTGSNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS Y D LPT+ +E G +RDL +EQ ++ +G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTHYYDALPTEGNE-HGQAFRDLRLEQELLKEAHKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPPALRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E +E+ + LP YIK+
Sbjct: 357 DAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKERIESGEDLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|ZP_00831475.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Yersinia frederiksenii ATCC
33641]
Length = 547
Score = 870 bits (2249), Expect = 0.0, Method: Composition-based stats.
Identities = 329/543 (60%), Positives = 423/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY LV+ ++VSV +ILKVE LTLLA A D
Sbjct: 2 SNKPFHYQDPFP-LKEDDTEYYLVSNNHVSVAQFEGH--DILKVEPEALTLLAQHAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I +DP+AS+ND++VALQ ++N+ I+A ILP CQDTGTAII G KG
Sbjct: 59 SFLLRPAHQKQVAAILDDPQASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +Y
Sbjct: 119 QRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGEDY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F FV KGGGSANK +L+QETK++L+P L+++L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLFVTKGGGSANKTYLYQETKALLSPGKLKDYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD+++EQ +++ +++G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDIQLEQELLEAAQDLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE +
Sbjct: 298 VRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-HSTEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK+
Sbjct: 357 KVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|YP_001929009.1| fumarate hydratase class I anaerobic [Porphyromonas gingivalis ATCC
33277]
dbj|BAG33412.1| fumarate hydratase class I anaerobic [Porphyromonas gingivalis ATCC
33277]
Length = 548
Score = 870 bits (2248), Expect = 0.0, Method: Composition-based stats.
Identities = 337/543 (62%), Positives = 421/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
+ P FK+ P + TEY L+TK+YVSV G ++LKVE L LLA A D+
Sbjct: 2 ATPEFKYQKPFP-MGDDTTEYYLLTKEYVSVDKFGDH--DVLKVEPEALRLLARTAFHDI 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
+LRP H + I DPEAS+ND+FVAL ++NA ++A LP CQDTGTAII G KG
Sbjct: 59 AFYLRPEHQQQVARILSDPEASENDKFVALTFLRNAEVSAKGQLPFCQDTGTAIILGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
+QV+T G DEE LS GV+ YT NLRYSQN PL MY E NTGCNLPAQIDL A G EY
Sbjct: 119 QQVWTGGHDEEQLSHGVYDTYTQENLRYSQNAPLDMYKEVNTGCNLPAQIDLMAVDGMEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++LNPK+L NFL +K+S++GT+ACPPYH+A V+GGTSA
Sbjct: 179 DFLCIAKGGGSANKTYLYQETKALLNPKTLVNFLVDKMSSLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY D LPT +E G +RD+E+E+ V++ +G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDNLPTSGNEG-GRAFRDVELEKEVLEAAYRLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
R+IR+PRHGASCP+G+GVSCSADR AKINKDGIW+EK+E +P + +PE + +
Sbjct: 298 VRIIRLPRHGASCPVGMGVSCSADRNIKAKINKDGIWIEKMETNPTRLIPESMRE-GTEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E ++ + LPDY+KN
Sbjct: 357 TVVKVDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERIDRGEGLPDYVKN 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P+ + SGSFGPTTAGRMD +VDLFQ++GGS VM+AKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPKGMPSGSFGPTTAGRMDSYVDLFQSHGGSMVMIAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
YGGFYLGS+GGPAA+LA DSI+KVE L+ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 477 YGGFYLGSVGGPAAILAQDSIKKVECLEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFT 536
Query: 553 QLR 555
Q+R
Sbjct: 537 QIR 539
>ref|ZP_02685331.1| fumarase B [Salmonella enterica subsp. enterica serovar Hadar str.
RI_05P066]
Length = 548
Score = 869 bits (2247), Expect = 0.0, Method: Composition-based stats.
Identities = 328/542 (60%), Positives = 408/542 (75%), Gaps = 5/542 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S F + P + TEY L+T DYVSV IL VE LTLLA +A D
Sbjct: 2 SKKEFIYQAPFP-MGEDKTEYYLLTSDYVSVSEFNG--ESILNVEPQALTLLAQQAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G KG
Sbjct: 59 SFMLRPEHQQQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIMGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G DE ALS+GV + Y NLRYSQN PL MY E NTG NLPAQIDLYA G EY
Sbjct: 119 QRVWTGGGDEAALSKGVFNTYIEDNLRYSQNAPLDMYKEVNTGSNLPAQIDLYAVDGDEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS Y D LP + +E G +RD +EQ +++ + +G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTHYYDALPAEGNE-HGQAFRDPHLEQELLEEAQKLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P +
Sbjct: 298 IRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPPALRQAG-EG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E +E+ + LP YIK+
Sbjct: 357 DAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKERIESGEDLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQQSIKHLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QL 554
Q+
Sbjct: 537 QI 538
>ref|ZP_00825174.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Yersinia mollaretii ATCC
43969]
Length = 547
Score = 869 bits (2246), Expect = 0.0, Method: Composition-based stats.
Identities = 331/543 (60%), Positives = 421/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY LV+ ++VSV +ILKVE LTLLA A D
Sbjct: 2 SNKPFHYQDPFP-LKEDDTEYYLVSNNHVSVAQFEGH--DILKVEPEALTLLAQHAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G KG
Sbjct: 59 SFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
+ V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +Y
Sbjct: 119 QCVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYREVNTGTNLPAQIDLYSTEGEDY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F FV KGGGSANK +L+QETK++L+P L+ +L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLFVTKGGGSANKTYLYQETKALLSPGKLKEYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD+ +EQ +++ +++G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDIALEQELLEAAQDLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE Q +
Sbjct: 298 VRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-QSNEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK+
Sbjct: 357 KVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
>ref|NP_905572.1| fumarate hydratase class I, anaerobic [Porphyromonas gingivalis
W83]
gb|AAQ66471.1| fumarate hydratase class I, anaerobic [Porphyromonas gingivalis
W83]
Length = 548
Score = 869 bits (2246), Expect = 0.0, Method: Composition-based stats.
Identities = 338/543 (62%), Positives = 422/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
+ P FK+ P + TEY L+TK+YVSV G ++LKVE L LLA A D+
Sbjct: 2 ATPEFKYQKPFP-MGDDTTEYYLLTKEYVSVDKFGDH--DVLKVEPEALRLLARTAFHDI 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
+LRP H + I DPEAS+ND+FVAL ++NA ++A LP CQDTGTAII G KG
Sbjct: 59 AFYLRPEHQQQVARILSDPEASENDKFVALTFLRNAEVSAKGQLPFCQDTGTAIILGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
+QV+T G DEE LS GV+ YT NLRYSQN PL MY E NTGCNLPAQIDL A G EY
Sbjct: 119 QQVWTGGHDEEQLSHGVYDTYTQENLRYSQNAPLDMYKEVNTGCNLPAQIDLMAVDGMEY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F +AKGGGSANK +L+QETK++LNPK+L NFL +K+S++GT+ACPPYH+A V+GGTSA
Sbjct: 179 DFLCIAKGGGSANKTYLYQETKALLNPKTLVNFLVDKMSSLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E +K VK AS KY D LPT +E G +RD+E+E+ V++ ++G+GAQFGGKYFAHD
Sbjct: 239 ETNLKTVKLASAKYYDNLPTSGNEG-GRAFRDVELEKEVLEAAYHLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
R+IR+PRHGASCP+G+GVSCSADR AKINKDGIW+EK+E +P + +PE + +
Sbjct: 298 VRIIRLPRHGASCPVGMGVSCSADRNIKAKINKDGIWIEKMETNPTRLIPESMRE-GTEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VK+DLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E ++ + LPDYIKN
Sbjct: 357 TVVKVDLNRPMPEILRELSQYPVSTRLSLSGTIIVGRDIAHAKLKERIDRGEGLPDYIKN 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK P+ + SGSFGPTTAGRMD +VDLFQ++GGS VM+AKGNRS++VT+ACKK
Sbjct: 417 HPIYYAGPAKTPKGMPSGSFGPTTAGRMDSYVDLFQSHGGSMVMIAKGNRSQQVTDACKK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
YGGFYLGS+GGPAA+LA DSI+KVE L+ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 477 YGGFYLGSVGGPAAILAQDSIKKVECLEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFT 536
Query: 553 QLR 555
Q+R
Sbjct: 537 QIR 539
>ref|ZP_00835117.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Yersinia intermedia ATCC
29909]
Length = 547
Score = 868 bits (2245), Expect = 0.0, Method: Composition-based stats.
Identities = 327/543 (60%), Positives = 420/543 (77%), Gaps = 5/543 (0%)
Query: 13 SAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGDV 72
S PF + P L DTEY LV+ ++VSV ++LKVE LTLLA A D
Sbjct: 2 SNKPFHYQDPFP-LKEDDTEYYLVSNNHVSVTQFEGH--DMLKVEPEALTLLAQHAFHDA 58
Query: 73 QHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYKG 132
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G KG
Sbjct: 59 SFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKKG 118
Query: 133 EQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCEY 192
++V+T G+D +ALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +Y
Sbjct: 119 QRVWTGGNDAQALSRGVYNTFIEDNLRYSQNAALDMYQEVNTGTNLPAQIDLYSTEGEDY 178
Query: 193 EFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTSA 252
+F FV KGGGSANK +L+QETK++L+P L+ +L EK+ T+GT+ACPPYH+A V+GGTSA
Sbjct: 179 KFLFVTKGGGSANKTYLYQETKALLSPGKLKEYLVEKMRTLGTAACPPYHIAFVIGGTSA 238
Query: 253 EMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAHD 312
E T+K VK AS KY D LPT+ +E G +RD +EQ +++ +++G+GAQFGGKYFAHD
Sbjct: 239 ESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDTALEQELLEAAQDLGLGAQFGGKYFAHD 297
Query: 313 ARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLKV 372
RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+E+LE +P +Y+PE Q +
Sbjct: 298 VRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLERLEQNPGQYIPEHLR-QSTEG 356
Query: 373 PPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIKN 432
VKIDLN PM I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK+
Sbjct: 357 KVVKIDLNRPMADILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIKD 416
Query: 433 HPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACKK 492
HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC K
Sbjct: 417 HPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHK 476
Query: 493 YGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFFQ 552
+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFFQ
Sbjct: 477 HGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQ 536
Query: 553 QLR 555
Q++
Sbjct: 537 QIQ 539
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|YP_689106.1| Fumarate hydratase class I, aerobic [Shige... 885 0.0
ref|NP_416129.1| fumarate hydratase (fumarase A), aerobic C... 885 0.0
ref|YP_310482.1| fumarase A [Shigella sonnei Ss046] >gi|752... 884 0.0
ref|YP_001743642.1| fumarate hydratase [Escherichia coli SM... 884 0.0
ref|ZP_00922444.1| COG1951: Tartrate dehydratase alpha subu... 883 0.0
ref|NP_707511.1| fumarase A, fumarate hydratase Class I; ae... 883 0.0
ref|YP_403430.1| fumarase A [Shigella dysenteriae Sd197] >g... 881 0.0
ref|NP_288047.1| fumarase A = fumarate hydratase Class I; a... 881 0.0
ref|ZP_02904384.1| fumarate hydratase class I, anaerobic [E... 881 0.0
ref|NP_756975.1| Fumarate hydratase class I, anaerobic [Esc... 880 0.0
ref|YP_313027.1| fumarase B [Shigella sonnei Ss046] >gi|752... 879 0.0
ref|ZP_02646500.1| hypothetical protein Senterenterica_1279... 879 0.0
ref|YP_410570.1| fumarase B [Shigella boydii Sb227] >gi|812... 878 0.0
ref|YP_001726834.1| hydro-lyase, Fe-S type, tartrate/fumara... 878 0.0
gb|EEH92879.1| fumarate hydratase class I [Citrobacter sp. ... 878 0.0
ref|ZP_00722640.1| COG1951: Tartrate dehydratase alpha subu... 878 0.0
ref|YP_001746516.1| fumarate hydratase class I, anaerobic [... 878 0.0
ref|ZP_00925876.1| COG1951: Tartrate dehydratase alpha subu... 877 0.0
ref|NP_418546.1| anaerobic class I fumarate hydratase (fuma... 877 0.0
ref|NP_313131.1| fumarase B [Escherichia coli O157:H7 str. ... 877 0.0
ref|ZP_02739706.1| fumarase B [Escherichia coli O157:H7 str... 876 0.0
gb|AAA23827.1| anaerobic class I fumarase (EC 4.2.1.2) 876 0.0
gb|AAA97022.1| fumarase [Escherichia coli] 876 0.0
ref|ZP_03836673.1| fumarate hydratase class I, aerobic [Cit... 875 0.0
ref|YP_691399.1| Fumarate hydratase class I, anaerobic [Shi... 875 0.0
ref|NP_709819.1| fumarase B, fumarate hydratase Class I [Sh... 875 0.0
ref|NP_290755.1| fumarase B= fumarate hydratase Class I; an... 874 0.0
ref|YP_001453190.1| hypothetical protein CKO_01623 [Citroba... 873 0.0
ref|YP_001455261.1| hypothetical protein CKO_03749 [Citroba... 872 0.0
ref|NP_406801.1| fumarate hydratase, class I [Yersinia pest... 872 0.0
ref|YP_001176561.1| hydro-lyase, Fe-S type, tartrate/fumara... 871 0.0
ref|YP_001438056.1| hypothetical protein ESA_01967 [Enterob... 871 0.0
ref|YP_001722124.1| hydro-lyase, Fe-S type, tartrate/fumara... 871 0.0
ref|YP_001335207.1| fumarase B (fumarate hydratase class I)... 871 0.0
ref|YP_001480245.1| hydro-lyase, Fe-S type, tartrate/fumara... 870 0.0
ref|YP_001402228.1| fumarate hydratase, class I [Yersinia p... 870 0.0
ref|ZP_00822736.1| COG1951: Tartrate dehydratase alpha subu... 869 0.0
ref|YP_001005156.1| fumarate hydratase, class I [Yersinia e... 869 0.0
ref|YP_001177280.1| hydro-lyase, Fe-S type, tartrate/fumara... 869 0.0
ref|ZP_02561418.1| fumarase B [Salmonella enterica subsp. e... 868 0.0
ref|YP_001335177.1| fumarase A (fumarate hydratase class I)... 868 0.0
ref|ZP_00835117.1| COG1951: Tartrate dehydratase alpha subu... 867 0.0
ref|ZP_02685331.1| fumarase B [Salmonella enterica subsp. e... 867 0.0
ref|ZP_03833166.1| fumarate hydratase class I, aerobic [Pec... 866 0.0
ref|ZP_00831475.1| COG1951: Tartrate dehydratase alpha subu... 866 0.0
ref|NP_463165.1| fumarase B [Salmonella typhimurium LT2] >g... 866 0.0
ref|YP_049013.1| fumarate hydratase class I, aerobic [Erwin... 865 0.0
ref|ZP_03828861.1| fumarate hydratase class I, aerobic [Pec... 865 0.0
ref|ZP_02903194.1| fumarate hydratase [Escherichia albertii... 865 0.0
ref|ZP_00825174.1| COG1951: Tartrate dehydratase alpha subu... 865 0.0
ref|YP_001929009.1| fumarate hydratase class I anaerobic [P... 864 0.0
ref|NP_905572.1| fumarate hydratase class I, anaerobic [Por... 863 0.0
ref|NP_460429.1| fumarase A [Salmonella typhimurium LT2] >g... 863 0.0
ref|ZP_02665916.1| Fumarate hydratase class I, aerobic [Sal... 861 0.0
ref|ZP_02345313.1| hypothetical protein Sentente_13804 [Sal... 861 0.0
ref|YP_001588077.1| hypothetical protein SPAB_01851 [Salmon... 861 0.0
ref|YP_216472.1| fumarase A (fumarate hydratase class I), a... 861 0.0
ref|ZP_02564600.1| hypothetical protein Senten_02232 [Salmo... 860 0.0
ref|YP_150641.1| Fumarate hydratase class I, aerobic [Salmo... 860 0.0
ref|NP_456064.1| Fumarate hydratase class I, aerobic [Salmo... 860 0.0
ref|ZP_02351328.1| hypothetical protein Sententeri_15956 [S... 860 0.0
ref|ZP_02649455.1| hypothetical protein Sententeric_00485 [... 859 0.0
ref|ZP_02559788.1| Fumarate hydratase class I, aerobic [Sal... 859 0.0
ref|ZP_02338828.1| hypothetical protein Sentent_08256 [Salm... 858 0.0
ref|YP_001570548.1| hypothetical protein SARI_01510 [Salmon... 855 0.0
gb|EEJ97739.1| fumarase [Thermomonospora curvata DSM 43183] 854 0.0
ref|ZP_03838974.1| hypothetical protein CATC2_23480 [Citrob... 853 0.0
gb|EEH96136.1| conserved hypothetical protein [Citrobacter ... 852 0.0
ref|YP_001572321.1| hypothetical protein SARI_03347 [Salmon... 851 0.0
ref|YP_001591410.1| hypothetical protein SPAB_05302 [Salmon... 851 0.0
ref|ZP_02668652.1| hypothetical protein Senterienterica_188... 851 0.0
ref|YP_631365.1| fumarate hydratase, class I [Myxococcus xa... 851 0.0
ref|NP_458599.1| fumarate hydratase class I [Salmonella ent... 850 0.0
ref|ZP_02700852.1| fumarate hydratase class I [Salmonella e... 850 0.0
ref|YP_153174.1| fumarate hydratase class I [Salmonella ent... 849 0.0
ref|YP_001299156.1| anaerobic fumarate hydratase class I [B... 849 0.0
ref|ZP_02346001.1| fumarate hydratase class I [Salmonella e... 849 0.0
ref|YP_219166.1| fumarase B (fumarate hydratase class I), a... 849 0.0
ref|ZP_02565856.1| fumarate hydratase class I [Salmonella e... 848 0.0
ref|ZP_02437159.1| hypothetical protein BACSTE_03432 [Bacte... 848 0.0
ref|ZP_02349309.1| fumarate hydratase class I [Salmonella e... 848 0.0
ref|YP_097958.1| anaerobic fumarate hydratase class I [Bact... 848 0.0
ref|NP_824394.1| fumarate hydratase class I [Streptomyces a... 848 0.0
ref|ZP_01961337.1| hypothetical protein BACCAC_02968 [Bacte... 847 0.0
ref|ZP_02072327.1| hypothetical protein BACUNI_03773 [Bacte... 846 0.0
ref|ZP_02066092.1| hypothetical protein BACOVA_03087 [Bacte... 845 0.0
ref|XP_828580.1| fumarate hydratase class I [Trypanosoma br... 845 0.0
ref|NP_811169.1| fumarate hydratase class I, anaerobic [Bac... 845 0.0
ref|YP_001823993.1| putative fumarate hydratase class I [St... 843 0.0
ref|ZP_02030648.1| hypothetical protein PARMER_00620 [Parab... 843 0.0
ref|NP_629196.1| fumarate hydratase class I [Streptomyces c... 843 0.0
ref|YP_001907860.1| Fumarase A [Erwinia tasmaniensis] >gi|1... 841 0.0
ref|ZP_03878233.1| fumarase [Haliangium ochraceum DSM 14365... 841 0.0
emb|CAM74591.1| Tartrate dehydratase alpha subunit/Fumarate... 840 0.0
gb|ACO63163.1| putative fumarate hydratase class1-malate <=... 839 0.0
ref|YP_001304100.1| fumarate hydratase class I, anaerobic [... 838 0.0
ref|YP_001878733.1| hydro-lyase, Fe-S type, tartrate/fumara... 838 0.0
ref|XP_804521.1| fumarate hydratase, putative [Trypanosoma ... 838 0.0
ref|XP_782370.2| PREDICTED: similar to SJCHGC09380 protein ... 838 0.0
ref|XP_817100.1| fumarate hydratase, putative [Trypanosoma ... 837 0.0
ref|YP_001241352.1| fumarase A (fumarate hydratase class I)... 836 0.0
ref|YP_420694.1| Fumarate hydratase class I aerobic [Magnet... 835 0.0
ref|YP_846452.1| hydro-lyases, Fe-S type, tartrate/fumarate... 834 0.0
ref|NP_949213.1| fumarate hydratase, class I [Rhodopseudomo... 834 0.0
ref|ZP_03859476.1| fumarase [Kribbella flavida DSM 17836] >... 834 0.0
ref|YP_001258929.1| fumarate hydratase, class I [Brucella o... 833 0.0
ref|YP_531414.1| hydro-lyases, Fe-S type, tartrate/fumarate... 833 0.0
ref|YP_119417.1| putative fumarate hydratase [Nocardia farc... 832 0.0
ref|NP_539933.1| FUMARATE HYDRATASE CLASS I, AEROBIC [Bruce... 832 0.0
ref|ZP_02302798.1| hydro-lyase, Fe-S type, tartrate/fumarat... 832 0.0
ref|ZP_01547699.1| Fumarate lyase [Stappia aggregata IAM 12... 832 0.0
ref|YP_385514.1| Fe-S type hydro-lyase tartrate/fumarate al... 832 0.0
ref|NP_697971.1| fumarate hydratase, class I [Brucella suis... 831 0.0
gb|EEJ99437.1| fumarase [Tsukamurella paurometabola DSM 20162] 831 0.0
ref|YP_001627633.1| hydro-lyase, Fe-S type, tartrate/fumara... 831 0.0
ref|XP_001745789.1| predicted protein [Monosiga brevicollis... 831 0.0
ref|ZP_01774525.1| hydro-lyase, Fe-S type, tartrate/fumarat... 830 0.0
ref|YP_001206931.1| fumarase A (fumarate hydratase class I)... 830 0.0
ref|YP_487367.1| Fumarate hydratase, class I [Rhodopseudomo... 829 0.0
ref|YP_001610994.1| hypothetical protein sce0357 [Sorangium... 829 0.0
ref|YP_001592802.1| hydro-lyase, Fe-S type, tartrate/fumara... 829 0.0
ref|ZP_02753357.1| fumarase A [Escherichia coli O157:H7 str... 829 0.0
ref|ZP_02013449.1| hydro-lyase, Fe-S type, tartrate/fumarat... 829 0.0
gb|AAW26769.1| SJCHGC09380 protein [Schistosoma japonicum] 827 0.0
ref|YP_568845.1| hydro-lyases, Fe-S type, tartrate/fumarate... 827 0.0
ref|ZP_02187346.1| Fumarate hydratase class I aerobic [alph... 826 0.0
ref|YP_001370770.1| hydro-lyase, Fe-S type, tartrate/fumara... 826 0.0
ref|NP_772436.1| Fumarate hydratase class I [Bradyrhizobium... 826 0.0
gb|EDT29778.1| fumarate hydratase class I, anaerobic (Fumar... 824 0.0
ref|YP_780500.1| hydro-lyases, Fe-S type, tartrate/fumarate... 824 0.0
ref|YP_001380232.1| hydro-lyase, Fe-S type, tartrate/fumara... 824 0.0
ref|YP_465275.1| fumarase [Anaeromyxobacter dehalogenans 2C... 823 0.0
ref|ZP_03925560.1| fumarate hydratase class I [Actinomyces ... 821 0.0
ref|XP_001696634.1| fumarate hydratase [Chlamydomonas reinh... 821 0.0
ref|YP_705834.1| fumarate hydratase class I [Rhodococcus sp... 820 0.0
ref|ZP_02166775.1| Fumarate lyase:Fe-S type hydro-lyase tar... 819 0.0
ref|YP_001234467.1| hydro-lyase, Fe-S type, tartrate/fumara... 819 0.0
ref|ZP_03815532.1| fumarase [Actinosynnema mirum DSM 43827]... 818 0.0
ref|XP_001565298.1| fumarate hydratase, putative [Leishmani... 818 0.0
ref|ZP_02858786.1| hydro-lyase, Fe-S type, tartrate/fumarat... 818 0.0
ref|NP_952048.1| fumarate hydratase, class I [Geobacter sul... 817 0.0
ref|YP_745628.1| fumarate hydratase [Granulibacter bethesde... 816 0.0
ref|ZP_02174352.1| hydro-lyase, Fe-S type, tartrate/fumarat... 816 0.0
ref|ZP_02297379.1| hydro-lyase, Fe-S type, tartrate/fumarat... 816 0.0
ref|XP_001683549.1| fumarate hydratase, putative [Leishmani... 816 0.0
ref|YP_768288.1| utative fumarate hydratase class I, aerobi... 815 0.0
ref|YP_002767658.1| fumarate hydratase class I [Rhodococcus... 814 0.0
ref|YP_001817521.1| hydro-lyase, Fe-S type, tartrate/fumara... 814 0.0
ref|ZP_02323626.1| hydro-lyase, Fe-S type, tartrate/fumarat... 814 0.0
ref|YP_900437.1| hydro-lyases, Fe-S type, tartrate/fumarate... 813 0.0
ref|YP_922266.1| hydro-lyases, Fe-S type, tartrate/fumarate... 810 0.0
ref|YP_001840478.1| Fumarate hydratase class I, aerobic (Fu... 809 0.0
ref|ZP_03922648.1| fumarate hydratase class I [Mobiluncus c... 808 0.0
ref|ZP_00993841.1| fumarate hydratase class I [Janibacter s... 808 0.0
ref|ZP_00831149.1| COG1951: Tartrate dehydratase alpha subu... 807 0.0
ref|ZP_01312990.1| hydro-lyases, Fe-S type, tartrate/fumara... 807 0.0
ref|YP_001008178.1| fumarate hydratase class I, anaerobic [... 806 0.0
ref|YP_001230419.1| hydro-lyase, Fe-S type, tartrate/fumara... 806 0.0
ref|ZP_00832031.1| COG1951: Tartrate dehydratase alpha subu... 806 0.0
ref|ZP_02981625.1| hydro-lyase, Fe-S type, tartrate/fumarat... 805 0.0
ref|XP_001566537.1| fumarate hydratase, putative [Leishmani... 804 0.0
ref|YP_001104025.1| fumarate hydratase class I [Saccharopol... 804 0.0
ref|YP_001601151.1| Fumarate hydratase class [Gluconacetoba... 804 0.0
ref|YP_002783153.1| fumarate hydratase class I [Rhodococcus... 803 0.0
ref|YP_001833973.1| hydro-lyase, Fe-S type, tartrate/fumara... 803 0.0
ref|XP_001466723.1| fumarate hydratase [Leishmania infantum... 803 0.0
gb|ABF20402.1| fumarate hydratase [Leishmania tropica] 802 0.0
gb|ABF20401.1| fumarate hydratase [Leishmania infantum] 801 0.0
ref|ZP_02132117.1| hydro-lyase, Fe-S type, tartrate/fumarat... 801 0.0
gb|ABF20395.1| fumarate hydratase [Leishmania infantum] 801 0.0
ref|XP_847862.1| fumarate hydratase, putative [Leishmania m... 801 0.0
gb|ABF20376.1| fumarate hydratase [Leishmania infantum] 801 0.0
ref|XP_001417167.1| predicted protein [Ostreococcus lucimar... 800 0.0
ref|YP_427293.1| tartrate dehydrogenase [Rhodospirillum rub... 799 0.0
ref|ZP_02424765.1| hypothetical protein ALIPUT_00893 [Alist... 799 0.0
gb|ABF20398.1| fumarate hydratase [Leishmania donovani arch... 798 0.0
ref|YP_679867.1| fumarate hydratase, class I [Cytophaga hut... 797 0.0
ref|ZP_02959159.1| hypothetical protein PROSTU_00957 [Provi... 796 0.0
gb|ABF20388.1| fumarate hydratase [Leishmania infantum] 794 0.0
ref|XP_814517.1| fumarate hydratase, putative [Trypanosoma ... 794 0.0
ref|ZP_01909505.1| fumarate hydratase, class I [Plesiocysti... 793 0.0
ref|YP_867134.1| hydro-lyases, Fe-S type, tartrate/fumarate... 791 0.0
ref|XP_821204.1| fumarate hydratase, putative [Trypanosoma ... 791 0.0
ref|XP_844042.1| fumarate hydratase, putative [Trypanosoma ... 789 0.0
emb|CAL51520.1| fumarate hydratase class I (ISS) [Ostreococ... 789 0.0
ref|YP_001453977.1| hypothetical protein CKO_02424 [Citroba... 787 0.0
gb|EEH92162.1| conserved hypothetical protein [Citrobacter ... 786 0.0
ref|NP_968997.1| fumarate hydratase, class I [Bdellovibrio ... 784 0.0
ref|YP_001161051.1| hydro-lyase, Fe-S type, tartrate/fumara... 783 0.0
ref|ZP_03835909.1| hypothetical protein CATC2_07906 [Citrob... 782 0.0
ref|YP_001193234.1| hydro-lyase, Fe-S type, tartrate/fumara... 782 0.0
ref|YP_001742833.1| hydro-lyase, Fe-S type, tartrate/fumara... 781 0.0
ref|YP_001539419.1| hydro-lyase, Fe-S type, tartrate/fumara... 781 0.0
ref|ZP_03850894.1| fumarate hydratase [Chryseobacterium gle... 779 0.0
ref|NP_286449.1| putative fumarate hydratase [Escherichia c... 779 0.0
ref|YP_469892.1| fumarate hydratase class I protein [Rhizob... 773 0.0
ref|YP_856949.1| fumarate hydratase, class I [Aeromonas hyd... 771 0.0
ref|YP_001571219.1| hypothetical protein SARI_02205 [Salmon... 771 0.0
ref|ZP_01733811.1| fumarate hydratase, class I [Flavobacter... 770 0.0
ref|ZP_00417946.1| Fe-S type hydro-lyases tartrate/fumarate... 767 0.0
ref|ZP_01876100.1| fumarate hydratase, class I [Lentisphaer... 766 0.0
ref|YP_002800960.1| fumarate hydratase, class I [Azotobacte... 762 0.0
ref|YP_350180.1| Fe-S type hydro-lyase tartrate/fumarate al... 761 0.0
ref|ZP_02000730.1| fumarate hydratase, class I, anaerobic [... 761 0.0
ref|YP_261882.1| fumarate hydratase, class I, putative [Pse... 760 0.0
ref|YP_001188750.1| hydro-lyase, Fe-S type, tartrate/fumara... 760 0.0
ref|YP_237099.1| Fe-S type hydro-lyase tartrate/fumarate al... 759 0.0
ref|YP_001341191.1| hydro-lyase, Fe-S type, tartrate/fumara... 757 0.0
ref|NP_794095.1| fumarate hydratase, class I, putative [Pse... 757 0.0
ref|YP_001670678.1| hydro-lyase, Fe-S type, tartrate/fumara... 757 0.0
ref|XP_001734600.1| fumarate hydratase class I, anaerobic, ... 756 0.0
ref|YP_001350238.1| fumarate hydratase, class I [Pseudomona... 756 0.0
ref|YP_001171684.1| probable fumarase [Pseudomonas stutzeri... 756 0.0
ref|YP_606854.1| fumarate hydratase, class I [Pseudomonas e... 756 0.0
ref|YP_276169.1| fumarate hydratase, class I, putative [Pse... 756 0.0
ref|YP_001579270.1| hydro-lyase, Fe-S type, tartrate/fumara... 755 0.0
ref|YP_001747874.1| hydro-lyase, Fe-S type, tartrate/fumara... 755 0.0
ref|ZP_01235291.1| Putative fumarate hydratase, class I [Vi... 754 0.0
ref|YP_130595.1| Putative fumarate hydratase, class I [Phot... 754 0.0
ref|ZP_00986943.1| COG1951: Tartrate dehydratase alpha subu... 753 0.0
ref|YP_436102.1| Tartrate dehydratase alpha subunit/Fumarat... 753 0.0
ref|NP_743058.1| fumarate hydratase, class I [Pseudomonas p... 753 0.0
ref|YP_959303.1| hydro-lyases, Fe-S type, tartrate/fumarate... 753 0.0
ref|ZP_01221083.1| Putative fumarate hydratase, class I [Ph... 753 0.0
ref|ZP_01077265.1| probable fumarase [Marinomonas sp. MED12... 753 0.0
ref|NP_253023.1| probable fumarase [Pseudomonas aeruginosa ... 752 0.0
ref|ZP_01364002.1| hypothetical protein PaerPA_01001105 [Ps... 752 0.0
ref|ZP_02365109.1| hydro-lyases, Fe-S type, tartrate/fumara... 752 0.0
ref|NP_885804.1| putative fumarate hydratase [Bordetella pa... 752 0.0
ref|YP_106350.1| hydro-lyase, Fe-S type, tartrate/fumarate ... 751 0.0
emb|CAM32536.1| Fumarate hydratase protein [Herbaspirillum ... 751 0.0
ref|YP_001266281.1| hydro-lyase, Fe-S type, tartrate/fumara... 751 0.0
ref|ZP_02885805.1| hydro-lyase, Fe-S type, tartrate/fumarat... 751 0.0
ref|ZP_02357979.1| hydro-lyases, Fe-S type, tartrate/fumara... 750 0.0
ref|ZP_01330957.1| hypothetical protein BpseS_03000801 [Bur... 750 0.0
ref|ZP_00980069.1| COG1951: Tartrate dehydratase alpha subu... 750 0.0
ref|YP_001120114.1| hydro-lyases, Fe-S type, tartrate/fumar... 750 0.0
ref|ZP_02894165.1| hydro-lyase, Fe-S type, tartrate/fumarat... 750 0.0
ref|YP_440213.1| hydro-lyase, Fe-S type, tartrate/fumarate ... 750 0.0
ref|YP_001858166.1| hydro-lyase, Fe-S type, tartrate/fumara... 750 0.0
ref|NP_798252.1| fumarate hydratase, class I [Vibrio paraha... 750 0.0
ref|ZP_02405688.1| fumarate hydratase, class I [Burkholderi... 750 0.0
ref|ZP_02911362.1| hydro-lyase, Fe-S type, tartrate/fumarat... 750 0.0
ref|ZP_00380865.1| COG1951: Tartrate dehydratase alpha subu... 750 0.0
ref|YP_625721.1| hydro-lyases, Fe-S type, tartrate/fumarate... 750 0.0
ref|YP_774123.1| hydro-lyases, Fe-S type, tartrate/fumarate... 749 0.0
ref|ZP_01892241.1| Tartrate dehydratase alpha subunit/Fumar... 749 0.0
ref|ZP_01737188.1| Tartrate dehydratase alpha subunit/Fumar... 749 0.0
ref|YP_001899668.1| hydro-lyase, Fe-S type, tartrate/fumara... 749 0.0
ref|YP_001765502.1| hydro-lyase, Fe-S type, tartrate/fumara... 749 0.0
ref|YP_001808807.1| hydro-lyase, Fe-S type, tartrate/fumara... 749 0.0
ref|YP_110392.1| fumarate hydratase [Burkholderia pseudomal... 749 0.0
ref|YP_369761.1| Fe-S type hydro-lyase tartrate/fumarate [B... 749 0.0
ref|ZP_02465678.1| hydro-lyase, Fe-S type, tartrate/fumarat... 749 0.0
ref|YP_001629387.1| Fumarate hydratase class I anaerobic [B... 748 0.0
ref|ZP_02381373.1| hydro-lyases, Fe-S type, tartrate/fumara... 747 0.0
ref|ZP_01162226.1| Putative fumarate hydratase, class I [Ph... 747 0.0
ref|ZP_02008711.1| hydro-lyase, Fe-S type, tartrate/fumarat... 747 0.0
ref|YP_296439.1| Fe-S type hydro-lyase tartrate/fumarate al... 747 0.0
ref|YP_001020579.1| putative fumarate hydratase [Methylibiu... 747 0.0
ref|YP_001142090.1| fumarate hydratase, class I [Aeromonas ... 746 0.0
ref|YP_726983.1| fumarate hydratase class I [Ralstonia eutr... 746 0.0
ref|NP_230949.1| fumarate hydratase, class I, putative [Vib... 746 0.0
ref|ZP_02492649.1| fumarate hydratase [Burkholderia pseudom... 745 0.0
ref|ZP_01953547.1| fumarate hydratase, class I, putative [V... 745 0.0
ref|NP_520076.1| PROBABLE FUMARATE HYDRATASE PROTEIN [Ralst... 745 0.0
ref|ZP_01484995.1| hypothetical protein VchoV5_02002396 [Vi... 745 0.0
ref|YP_584421.1| hydro-lyases, Fe-S type, tartrate/fumarate... 744 0.0
ref|YP_001904287.1| fumarate hydratase [Xanthomonas campest... 744 0.0
ref|ZP_01104763.1| fumarate hydratase, class I, anaerobic [... 744 0.0
ref|ZP_01984559.1| fumarate hydratase, class I [Vibrio harv... 744 0.0
ref|YP_001352570.1| fumarate hydratase, class I [Janthinoba... 744 0.0
ref|ZP_01869058.1| fumarate hydratase, class I [Vibrio shil... 744 0.0
ref|ZP_01166939.1| probable fumarase [Oceanospirillum sp. M... 743 0.0
gb|ABA55852.1| hypothetical protein [Vibrio sp. DAT722] 743 0.0
ref|ZP_00945354.1| Fumarate hydratase [Ralstonia solanacear... 743 0.0
ref|YP_001445107.1| fumarate hydratase, class I [Vibrio har... 742 0.0
ref|YP_001895052.1| hydro-lyase, Fe-S type, tartrate/fumara... 742 0.0
ref|YP_001528580.1| hydro-lyase, Fe-S type, tartrate/fumara... 742 0.0
ref|NP_636789.1| fumarate hydratase [Xanthomonas campestris... 742 0.0
ref|YP_557895.1| tartrate/fumarate Fe-S type hydro-lyases [... 742 0.0
ref|YP_785244.1| fumarate hydratase [Bordetella avium 197N]... 742 0.0
ref|ZP_01043530.1| Fumarase B [Idiomarina baltica OS145] >g... 741 0.0
ref|YP_156087.1| Fumarase B [Idiomarina loihiensis L2TR] >g... 741 0.0
ref|YP_001501893.1| hydro-lyase, Fe-S type, tartrate/fumara... 741 0.0
ref|ZP_02194608.1| fumarate hydratase, class I [Vibrio camp... 741 0.0
ref|ZP_01307258.1| Tartrate dehydratase alpha subunit/Fumar... 740 0.0
ref|YP_001099230.1| fumarase A (fumarate hydratase class I)... 740 0.0
ref|NP_934872.1| fumarate hydratase, class I [Vibrio vulnif... 740 0.0
ref|ZP_01064590.1| fumarate hydratase, class I [Vibrio sp. ... 740 0.0
ref|NP_761117.1| Fumarate hydratase [Vibrio vulnificus CMCP... 740 0.0
ref|ZP_00991791.1| fumarate hydratase, class I [Vibrio sple... 740 0.0
ref|ZP_01116436.1| Tartrate dehydratase alpha subunit/Fumar... 740 0.0
ref|YP_001674474.1| hydro-lyase, Fe-S type, tartrate/fumara... 740 0.0
ref|NP_641794.1| fumarate hydratase [Xanthomonas axonopodis... 739 0.0
ref|YP_573885.1| hydro-lyases, Fe-S type, tartrate/fumarate... 739 0.0
ref|YP_200975.1| fumarate hydratase [Xanthomonas oryzae pv.... 739 0.0
ref|YP_693260.1| fumarate hydratase, putative [Alcanivorax ... 739 0.0
ref|ZP_01112233.1| fumarate hydratase, class I [Alteromonas... 739 0.0
ref|YP_523831.1| hydro-lyases, Fe-S type, tartrate/fumarate... 738 0.0
Sequences not found previously or not previously below threshold:
>ref|YP_689106.1| Fumarate hydratase class I, aerobic [Shigella flexneri 5 str. 8401]
gb|ABF03801.1| Fumarate hydratase class I, aerobic [Shigella flexneri 5 str. 8401]
Length = 548
Score = 885 bits (2288), Expect = 0.0, Method: Composition-based stats.
Identities = 333/544 (61%), Positives = 416/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 1 MSNKPFHYQSPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK
Sbjct: 356 GEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|NP_416129.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. MG1655]
ref|NP_753899.1| Fumarate hydratase class I, aerobic [Escherichia coli CFT073]
ref|ZP_00722811.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli F11]
ref|ZP_00926573.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli 101-1]
ref|AP_002233.1| aerobic Class I fumarate hydratase [Escherichia coli W3110]
ref|YP_540809.1| fumarase A [Escherichia coli UTI89]
ref|YP_669464.1| fumarate hydratase class I, aerobic [Escherichia coli 536]
ref|YP_852711.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
APEC O1]
ref|YP_001462901.1| fumarate hydratase [Escherichia coli E24377A]
ref|YP_001730596.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. DH10B]
sp|P0AC33|FUMA_ECOLI Fumarate hydratase class I, aerobic (Fumarase)
sp|P0AC34|FUMA_ECOL6 Fumarate hydratase class I, aerobic (Fumarase)
gb|AAN80464.1|AE016761_39 Fumarate hydratase class I, aerobic [Escherichia coli CFT073]
emb|CAA25204.1| unnamed protein product [Escherichia coli]
dbj|BAA15360.1| aerobic Class I fumarate hydratase [Escherichia coli W3110]
gb|AAC74684.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. MG1655]
gb|ABE07278.1| fumarase A [Escherichia coli UTI89]
gb|ABG69563.1| fumarate hydratase class I, aerobic [Escherichia coli 536]
gb|ABJ00997.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
APEC O1]
gb|ABV17591.1| fumarate hydratase [Escherichia coli E24377A]
gb|ACB02818.1| fumarate hydratase (fumarase A), aerobic Class I [Escherichia coli
str. K-12 substr. DH10B]
Length = 548
Score = 885 bits (2287), Expect = 0.0, Method: Composition-based stats.
Identities = 333/544 (61%), Positives = 416/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 1 MSNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK
Sbjct: 356 GEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|YP_310482.1| fumarase A [Shigella sonnei Ss046]
ref|ZP_00712947.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli B171]
ref|ZP_00717388.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli B7A]
ref|ZP_00719204.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli E110019]
ref|ZP_00728591.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli E22]
ref|YP_407968.1| fumarase A [Shigella boydii Sb227]
ref|YP_001458391.1| fumarate hydratase [Escherichia coli HS]
ref|YP_001724989.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Escherichia coli ATCC 8739]
ref|YP_001880366.1| fumarate hydratase [Shigella boydii CDC 3083-94]
ref|ZP_02999252.1| fumarate hydratase class I, aerobic [Escherichia coli 53638]
gb|AAZ88247.1| fumarase A [Shigella sonnei Ss046]
gb|ABB66140.1| fumarase A [Shigella boydii Sb227]
gb|ABV06008.1| fumarate hydratase [Escherichia coli HS]
gb|ACA77662.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Escherichia coli ATCC 8739]
gb|ACD09923.1| fumarate hydratase [Shigella boydii CDC 3083-94]
gb|EDU62284.1| fumarate hydratase class I, aerobic [Escherichia coli 53638]
Length = 548
Score = 884 bits (2286), Expect = 0.0, Method: Composition-based stats.
Identities = 333/544 (61%), Positives = 416/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 1 MSNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGCDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK
Sbjct: 356 GEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|YP_001743642.1| fumarate hydratase [Escherichia coli SMS-3-5]
gb|ACB18046.1| fumarate hydratase [Escherichia coli SMS-3-5]
Length = 548
Score = 884 bits (2285), Expect = 0.0, Method: Composition-based stats.
Identities = 334/544 (61%), Positives = 416/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 1 MSNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK
Sbjct: 356 GEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|ZP_00922444.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Shigella dysenteriae 1012]
Length = 548
Score = 883 bits (2284), Expect = 0.0, Method: Composition-based stats.
Identities = 333/544 (61%), Positives = 416/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 1 MSNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAKYYDELPTEGNE-HGQGFRDVELEKELLIEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK
Sbjct: 356 GEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|NP_707511.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 301]
ref|NP_837298.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 2457T]
gb|AAN43218.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 301]
gb|AAP17105.1| fumarase A, fumarate hydratase Class I; aerobic isozyme [Shigella
flexneri 2a str. 2457T]
Length = 548
Score = 883 bits (2283), Expect = 0.0, Method: Composition-based stats.
Identities = 333/544 (61%), Positives = 416/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 1 MSNKPFHYQSPFP-LKKNDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK
Sbjct: 356 GEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|YP_403430.1| fumarase A [Shigella dysenteriae Sd197]
gb|ABB61939.1| fumarase A [Shigella dysenteriae Sd197]
Length = 548
Score = 881 bits (2279), Expect = 0.0, Method: Composition-based stats.
Identities = 332/544 (61%), Positives = 415/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 1 MSNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEILKVAPEALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QE K++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQEAKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK
Sbjct: 356 GEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|NP_288047.1| fumarase A = fumarate hydratase Class I; aerobic isozyme
[Escherichia coli O157:H7 EDL933]
ref|NP_310345.1| fumarase A [Escherichia coli O157:H7 str. Sakai]
ref|ZP_02742709.1| fumarase A [Escherichia coli O157:H7 str. EC4045]
ref|ZP_02771017.1| fumarase A [Escherichia coli O157:H7 str. EC4115]
ref|ZP_02775598.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4113]
ref|ZP_02782481.1| fumarase A [Escherichia coli O157:H7 str. EC4401]
ref|ZP_02788693.1| fumarase A [Escherichia coli O157:H7 str. EC4501]
ref|ZP_02796159.1| fumarase A [Escherichia coli O157:H7 str. EC4486]
ref|ZP_02800847.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4196]
ref|ZP_02808440.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4076]
ref|ZP_02814454.1| fumarase A [Escherichia coli O157:H7 str. EC869]
ref|ZP_02820502.1| fumarase A [Escherichia coli O157:H7 str. EC4042]
ref|ZP_02825877.1| fumarase A [Escherichia coli O157:H7 str. EC508]
sp|Q8X4P8|FUMA_ECO57 Fumarate hydratase class I, aerobic (Fumarase)
gb|AAG56599.1|AE005384_9 fumarase A = fumarate hydratase Class I; aerobic isozyme
[Escherichia coli O157:H7 EDL933]
dbj|BAB35741.1| fumarase A [Escherichia coli O157:H7 str. Sakai]
gb|EDU32558.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4196]
gb|EDU53361.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4113]
gb|EDU68187.1| fumarate hydratase [Escherichia coli O157:H7 str. EC4076]
Length = 548
Score = 881 bits (2277), Expect = 0.0, Method: Composition-based stats.
Identities = 332/544 (61%), Positives = 416/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T ++VS+ EILKV LTLLA +A D
Sbjct: 1 MSNKPFHYQAPFP-LKKDDTEYYLLTSEHVSLSEFEG--QEILKVAPEALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK
Sbjct: 356 GEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQALGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|ZP_02904384.1| fumarate hydratase class I, anaerobic [Escherichia albertii
TW07627]
gb|EDS90156.1| fumarate hydratase class I, anaerobic [Escherichia albertii
TW07627]
Length = 548
Score = 881 bits (2277), Expect = 0.0, Method: Composition-based stats.
Identities = 330/543 (60%), Positives = 413/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVAEFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + SI DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVASILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L++FL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKDFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y D LPT+ +E G +RD+++EQ ++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDNLPTEGNE-HGQAFRDVQLEQELLKEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPEELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++P+ TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPISTRLSLTGTIIVGRDIAHAKLKELIDEGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPTGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|NP_756975.1| Fumarate hydratase class I, anaerobic [Escherichia coli CFT073]
ref|ZP_00723073.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli F11]
ref|YP_543654.1| fumarate hydratase class I, anaerobic [Escherichia coli UTI89]
ref|YP_672209.1| fumarate hydratase class I, anaerobic [Escherichia coli 536]
ref|YP_859731.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
APEC O1]
gb|AAN83549.1|AE016771_60 Fumarate hydratase class I, anaerobic [Escherichia coli CFT073]
gb|ABE10123.1| fumarate hydratase class I, anaerobic [Escherichia coli UTI89]
gb|ABG72308.1| fumarate hydratase class I, anaerobic [Escherichia coli 536]
gb|ABJ03607.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
APEC O1]
Length = 548
Score = 880 bits (2275), Expect = 0.0, Method: Composition-based stats.
Identities = 332/543 (61%), Positives = 416/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDELPTEGNE-HGQAFRDIQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPEELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|YP_313027.1| fumarase B [Shigella sonnei Ss046]
ref|ZP_00712106.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli B171]
ref|ZP_00717687.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli B7A]
ref|ZP_00730409.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli E22]
ref|YP_405623.1| fumarase B [Shigella dysenteriae Sd197]
ref|YP_001465621.1| fumarate hydratase [Escherichia coli E24377A]
ref|YP_001460906.1| fumarate hydratase [Escherichia coli HS]
ref|ZP_03002676.1| fumarate hydratase class I, anaerobic [Escherichia coli 53638]
gb|AAZ90792.1| fumarase B [Shigella sonnei Ss046]
gb|ABB64132.1| fumarase B [Shigella dysenteriae Sd197]
gb|ABV08523.1| fumarate hydratase [Escherichia coli HS]
gb|ABV19946.1| fumarate hydratase [Escherichia coli E24377A]
gb|EDU65708.1| fumarate hydratase class I, anaerobic [Escherichia coli 53638]
Length = 548
Score = 879 bits (2273), Expect = 0.0, Method: Composition-based stats.
Identities = 330/543 (60%), Positives = 415/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|ZP_02646500.1| hypothetical protein Senterenterica_12797 [Salmonella enterica
subsp. enterica serovar Agona str. SL483]
Length = 548
Score = 879 bits (2272), Expect = 0.0, Method: Composition-based stats.
Identities = 326/544 (59%), Positives = 414/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T ++VSV EILKV LTLLA +A D
Sbjct: 1 MSNKPFFYQDPFP-LKKDDTEYYLLTSEHVSVAEFEG--QEILKVAPEALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DP+AS+ND++VALQ ++N++IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPQASENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN L MY E NTG NLPAQIDLY+ G E
Sbjct: 118 GQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+N+L +K+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVDKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS KY D LPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AEANLKTVKLASAKYYDALPTEGNE-HGQAFRDIELEKELLFEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLERNPGKYIPEALRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I +LS++PV TRLSL GTIIV RDIAHA+++E ++ + LP YIK
Sbjct: 356 GEAVRVDLNRPMSEILQQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDRGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD Q+ GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQSQGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+++E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKRLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|YP_410570.1| fumarase B [Shigella boydii Sb227]
gb|ABB68742.1| fumarase B [Shigella boydii Sb227]
Length = 548
Score = 878 bits (2271), Expect = 0.0, Method: Composition-based stats.
Identities = 329/543 (60%), Positives = 414/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTG AII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGIAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|YP_001726834.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Escherichia coli ATCC 8739]
gb|ACA79507.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Escherichia coli ATCC 8739]
Length = 548
Score = 878 bits (2271), Expect = 0.0, Method: Composition-based stats.
Identities = 330/543 (60%), Positives = 414/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YRFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>gb|EEH92879.1| fumarate hydratase class I [Citrobacter sp. 30_2]
Length = 548
Score = 878 bits (2270), Expect = 0.0, Method: Composition-based stats.
Identities = 331/544 (60%), Positives = 416/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T DYVSV EI+KV LTLLA +A D
Sbjct: 1 MSNKPFHYQHPFP-LKKDDTEYYLLTSDYVSVAEFEG--QEIVKVAPQALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEAL+RGV++ Y NLRYSQN L MY E NTG NLPAQIDLY G E
Sbjct: 118 GQRVWTGGGDEEALARGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYTVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+++L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKDYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AEATLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P K++PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGKFIPEELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E L+N + LP Y+K
Sbjct: 356 GEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERLDNGESLPQYVK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAAGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
+Q++
Sbjct: 536 KQIQ 539
>ref|ZP_00722640.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli E110019]
Length = 548
Score = 878 bits (2270), Expect = 0.0, Method: Composition-based stats.
Identities = 329/543 (60%), Positives = 414/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGND F
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDLF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|YP_001746516.1| fumarate hydratase class I, anaerobic [Escherichia coli SMS-3-5]
gb|ACB17618.1| fumarate hydratase class I, anaerobic [Escherichia coli SMS-3-5]
Length = 548
Score = 878 bits (2269), Expect = 0.0, Method: Composition-based stats.
Identities = 331/543 (60%), Positives = 416/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F V+KGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVSKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDELPTEGNE-HGQAFRDIQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPEELRKAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|ZP_00925876.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Escherichia coli 101-1]
Length = 548
Score = 877 bits (2268), Expect = 0.0, Method: Composition-based stats.
Identities = 330/543 (60%), Positives = 415/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPDQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|NP_418546.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
str. K-12 substr. MG1655]
ref|AP_004623.1| anaerobic class I fumarate hydratase [Escherichia coli W3110]
ref|YP_001732892.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
str. K-12 substr. DH10B]
sp|P14407|FUMB_ECOLI Fumarate hydratase class I, anaerobic (Fumarase)
gb|AAC77083.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
str. K-12 substr. MG1655]
dbj|BAE78124.1| anaerobic class I fumarate hydratase [Escherichia coli W3110]
gb|ACB05114.1| anaerobic class I fumarate hydratase (fumarase B) [Escherichia coli
str. K-12 substr. DH10B]
Length = 548
Score = 877 bits (2268), Expect = 0.0, Method: Composition-based stats.
Identities = 329/543 (60%), Positives = 414/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEE LS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEETLSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|NP_313131.1| fumarase B [Escherichia coli O157:H7 str. Sakai]
ref|ZP_02785990.1| fumarase B [Escherichia coli O157:H7 str. EC4501]
dbj|BAB38527.1| fumarase B [Escherichia coli O157:H7 str. Sakai]
Length = 548
Score = 877 bits (2267), Expect = 0.0, Method: Composition-based stats.
Identities = 329/543 (60%), Positives = 413/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 VETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEKAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE P +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHHPGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|ZP_02739706.1| fumarase B [Escherichia coli O157:H7 str. EC4045]
ref|ZP_02751886.1| fumarase B [Escherichia coli O157:H7 str. EC4206]
ref|ZP_02769460.1| fumarase B [Escherichia coli O157:H7 str. EC4115]
ref|ZP_02773043.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4113]
ref|ZP_02780311.1| fumarase B [Escherichia coli O157:H7 str. EC4401]
ref|ZP_02791400.1| fumarase B [Escherichia coli O157:H7 str. EC4486]
ref|ZP_02799499.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4196]
ref|ZP_02805553.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4076]
ref|ZP_02809758.1| fumarase B [Escherichia coli O157:H7 str. EC869]
ref|ZP_02819581.1| fumarase B [Escherichia coli O157:H7 str. EC4042]
ref|ZP_02823212.1| fumarase B [Escherichia coli O157:H7 str. EC508]
gb|EDU33813.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4196]
gb|EDU55522.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4113]
gb|EDU70784.1| fumarate hydratase class I, anaerobic [Escherichia coli O157:H7
str. EC4076]
Length = 548
Score = 876 bits (2266), Expect = 0.0, Method: Composition-based stats.
Identities = 329/543 (60%), Positives = 413/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 VETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE P +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHHPGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>gb|AAA23827.1| anaerobic class I fumarase (EC 4.2.1.2)
Length = 548
Score = 876 bits (2264), Expect = 0.0, Method: Composition-based stats.
Identities = 328/543 (60%), Positives = 414/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTL+A +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLVAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEE LS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEETLSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>gb|AAA97022.1| fumarase [Escherichia coli]
Length = 548
Score = 876 bits (2264), Expect = 0.0, Method: Composition-based stats.
Identities = 328/543 (60%), Positives = 413/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTL A +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLXAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEE LS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEETLSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|ZP_03836673.1| fumarate hydratase class I, aerobic [Citrobacter youngae ATCC
29220]
Length = 548
Score = 875 bits (2263), Expect = 0.0, Method: Composition-based stats.
Identities = 330/544 (60%), Positives = 416/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T DYVSV E++KV LTLLA +A D
Sbjct: 1 MSNKPFHYQHPFP-LKKDDTEYYLLTSDYVSVAEFEG--QEVIKVAPQALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN L MY E NTG NLPAQIDLY+ G E
Sbjct: 118 GQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L+P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLSPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AEATLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR A IN++GIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAMINREGIWIEKLEHNPGKYIPEELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E L++ + LP YIK
Sbjct: 356 GEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERLDSGENLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAAGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
+Q++
Sbjct: 536 KQIQ 539
>ref|YP_691399.1| Fumarate hydratase class I, anaerobic [Shigella flexneri 5 str.
8401]
gb|ABF06094.1| Fumarate hydratase class I, anaerobic [Shigella flexneri 5 str.
8401]
Length = 548
Score = 875 bits (2263), Expect = 0.0, Method: Composition-based stats.
Identities = 329/543 (60%), Positives = 414/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE + +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNLGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|NP_709819.1| fumarase B, fumarate hydratase Class I [Shigella flexneri 2a str.
301]
ref|NP_838862.1| fumarase B, fumarate hydratase Class I [Shigella flexneri 2a str.
2457T]
gb|AAN45526.1| fumarase B, fumarate hydratase Class I [Shigella flexneri 2a str.
301]
gb|AAP18673.1| fumarase B, fumarate hydratase Class I [Shigella flexneri 2a str.
2457T]
Length = 548
Score = 875 bits (2261), Expect = 0.0, Method: Composition-based stats.
Identities = 329/543 (60%), Positives = 414/543 (76%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AENNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE + +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNLGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|NP_290755.1| fumarase B= fumarate hydratase Class I; anaerobic isozyme
[Escherichia coli O157:H7 EDL933]
gb|AAG59321.1|AE005645_7 fumarase B= fumarate hydratase Class I; anaerobic isozyme
[Escherichia coli O157:H7 EDL933]
Length = 548
Score = 874 bits (2260), Expect = 0.0, Method: Composition-based stats.
Identities = 328/543 (60%), Positives = 412/543 (75%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P + +TEY L+T DYVSV + ILKVE LTLLA +A D
Sbjct: 1 MSNKPFIYQAPFP-MGKDNTEYYLLTSDYVSVADFDG--ETILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DEEALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
E +K VK AS Y DELPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 VETNLKTVKLASAHYYDELPTEGNE-HGQAFRDVQLEQELLEKAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++ IW+EKLE P +Y+P+
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREXIWIEKLEHHPGQYIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E+++ K LP YIK
Sbjct: 356 GEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKELIDAGKELPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|YP_001453190.1| hypothetical protein CKO_01623 [Citrobacter koseri ATCC BAA-895]
gb|ABV12755.1| hypothetical protein CKO_01623 [Citrobacter koseri ATCC BAA-895]
Length = 548
Score = 873 bits (2257), Expect = 0.0, Method: Composition-based stats.
Identities = 326/544 (59%), Positives = 413/544 (75%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T ++VSV E+LKV LTL+A +A D
Sbjct: 1 MSNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVAEFEG--QEVLKVAPEALTLMARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DP+AS+ND++VALQ ++N++IAA ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPDASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLY+ G E
Sbjct: 118 GQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYSVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+N+L +K+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVDKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY DELPT+ +E G +RD+E+E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AEATLKTVKLASAKYYDELPTEGNE-HGQAFRDVELEKELLTEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+ GIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRKGIWIEKLEHNPGKYIPEELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM I +LS++PV TRLSL GTIIV RDIAHA+++E ++ + LP Y+K
Sbjct: 356 GEAVRVDLNQPMKAILQQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDRGEGLPQYVK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD Q+ GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQSQGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SIR +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIRSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|YP_001455261.1| hypothetical protein CKO_03749 [Citrobacter koseri ATCC BAA-895]
gb|ABV14825.1| hypothetical protein CKO_03749 [Citrobacter koseri ATCC BAA-895]
Length = 548
Score = 872 bits (2255), Expect = 0.0, Method: Composition-based stats.
Identities = 329/543 (60%), Positives = 410/543 (75%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S F + P + TEY L+T D+VSV ILKVE LTLLA +A D
Sbjct: 1 MSNKEFIYQAPFP-MGEDKTEYYLLTSDHVSVGEFEG--ESILKVEPQALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP H + SI DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPEHQQQVASILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE ALS+GV + Y NLRYSQN L MY E NTG NLPAQIDLY G E
Sbjct: 118 GQRVWTGGGDEAALSKGVFNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYTVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS Y D LPT+ +E G +RD+++EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASAHYYDGLPTEGNE-HGQAFRDIQLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +PA+Y+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPAQYIPESLRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSL+GTIIV RDIAHA+++E +E+ + LP YIK
Sbjct: 356 GEVVKVDLNRPMKEILAQLSQYPVSTRLSLSGTIIVGRDIAHAKLKERIESGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
KYGGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KYGGFYLGSIGGPAAVLAQQSIKHLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|NP_406801.1| fumarate hydratase, class I [Yersinia pestis CO92]
ref|NP_668188.1| fumarase A [Yersinia pestis KIM]
ref|NP_991748.1| fumarate hydratase, class I [Yersinia pestis biovar Microtus str.
91001]
ref|YP_069337.1| fumarase A (fumarate hydratase class I), aerobic isozyme [Yersinia
pseudotuberculosis IP 32953]
ref|YP_652716.1| fumarate hydratase, class I [Yersinia pestis Antiqua]
ref|YP_646690.1| fumarate hydratase, class I [Yersinia pestis Nepal516]
ref|YP_001164357.1| fumarate hydratase, class I [Yersinia pestis Pestoides F]
ref|ZP_02022718.1| fumarate hydratase, class I [Yersinia pestis CA88-4125]
ref|YP_001605497.1| fumarate hydratase, class I [Yersinia pestis Angola]
ref|ZP_02221496.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
F1991016]
ref|ZP_02225315.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
IP275]
ref|ZP_02231089.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
E1979001]
ref|ZP_02239036.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
B42003004]
ref|ZP_02305001.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
UG05-0454]
ref|ZP_02313292.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
MG05-1020]
ref|ZP_02315047.1| fumarate hydratase, class I [Yersinia pestis biovar Mediaevalis
str. K1973002]
ref|YP_001871272.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Yersinia pseudotuberculosis PB1/+]
gb|AAM84439.1|AE013688_4 fumarase A [Yersinia pestis KIM]
gb|AAS60625.1| fumarate hydratase, class I [Yersinia pestis biovar Microtus str.
91001]
emb|CAH20036.1| fumarase A (fumarate hydratase class I), aerobic isozyme [Yersinia
pseudotuberculosis IP 32953]
gb|ABG17090.1| fumarase [Yersinia pestis Nepal516]
gb|ABG14771.1| fumarase [Yersinia pestis Antiqua]
emb|CAL21926.1| fumarate hydratase, class I [Yersinia pestis CO92]
gb|ABP41384.1| fumarase [Yersinia pestis Pestoides F]
gb|EDM39335.1| fumarate hydratase, class I [Yersinia pestis CA88-4125]
gb|ABX87267.1| fumarate hydratase, class I [Yersinia pestis Angola]
gb|EDR34007.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
IP275]
gb|EDR39453.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
F1991016]
gb|EDR43399.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
E1979001]
gb|EDR50268.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
B42003004]
gb|EDR56479.1| fumarate hydratase, class I [Yersinia pestis biovar Orientalis str.
MG05-1020]
gb|EDR63389.1| fumarate hydratase, class I [Yersinia pestis biovar Antiqua str.
UG05-0454]
gb|EDR67210.1| fumarate hydratase, class I [Yersinia pestis biovar Mediaevalis
str. K1973002]
gb|ACC87815.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Yersinia pseudotuberculosis PB1/+]
Length = 547
Score = 872 bits (2254), Expect = 0.0, Method: Composition-based stats.
Identities = 332/544 (61%), Positives = 419/544 (77%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY LV+ +VSV +ILKVE LTLLA +A D
Sbjct: 1 MSNKPFHYQDPFP-LKEDDTEYYLVSDKHVSVAQFEGH--DILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G K
Sbjct: 58 ASFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIMGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G E
Sbjct: 118 GQRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGEE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F FV KGGGSANK +L+QETK++L P L+ FL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLFVTKGGGSANKTYLYQETKALLTPGRLKAFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD +EQ +++ +++G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDTALEQELLEAAQDLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE +
Sbjct: 297 DVRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-HSTE 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK
Sbjct: 356 GQVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|YP_001176561.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Enterobacter sp. 638]
gb|ABP60510.1| fumarase [Enterobacter sp. 638]
Length = 548
Score = 871 bits (2253), Expect = 0.0, Method: Composition-based stats.
Identities = 330/544 (60%), Positives = 415/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L TEY L+T+D+VSV EILKVE LTLLA +A D
Sbjct: 1 MSNKPFHYQNPFP-LSQDQTEYYLLTRDHVSVSEFEG--QEILKVEPQALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I D +AS+ND++VALQ ++N++IAA ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILSDLQASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIITGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+ GV++ Y NLRYSQN L MY E NTG NLPAQIDLY+ G E
Sbjct: 118 GQRVWTGGGDEAALAHGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L+P L+N+L EK+ ++GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLSPGKLKNYLVEKMRSLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD+++EQ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDIQLEQELLVEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +P KY+PE
Sbjct: 297 DVRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLEKNPGKYIPEALRKAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V +DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E LEN + LP Y+K
Sbjct: 356 GEAVHVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLQERLENGEGLPQYVK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QANGGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQANGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
+Q++
Sbjct: 536 KQIQ 539
>ref|YP_001438056.1| hypothetical protein ESA_01967 [Enterobacter sakazakii ATCC
BAA-894]
gb|ABU77220.1| hypothetical protein ESA_01967 [Enterobacter sakazakii ATCC
BAA-894]
Length = 548
Score = 871 bits (2252), Expect = 0.0, Method: Composition-based stats.
Identities = 335/544 (61%), Positives = 419/544 (77%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L +TEY L+T+D+VSV EILKVE LTLLA A D
Sbjct: 1 MSGKPFFWQEPFP-LKKDETEYYLLTRDHVSVSEFEG--QEILKVEPQALTLLARHAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N+ IAA ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILSDPEASENDKYVALQFLRNSEIAAKGILPTCQDTGTAIIMGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL++GV+ YT NLRYSQN L MY E NTG NLPAQIDLY+ G E
Sbjct: 118 GQRVWTGGGDEAALAQGVYQTYTQDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+ +L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKAYLVEKMRTLGTAACPPYHVAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD+++E+ ++ RN+G+GAQFGGKYFAH
Sbjct: 238 AEATLKTVKLASTKYYDGLPTEGNE-HGQAFRDVQLEEELLQEARNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLESNPGKYIPEALRRAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL+GTIIVARDIAHA+++E +++ LP Y+K
Sbjct: 356 GEAVRVDLNRPMSEILAQLSQYPVSTRLSLSGTIIVARDIAHAKLKERIDSGAGLPQYVK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL QANGGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQANGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SIR +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQNSIRHLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|YP_001722124.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Yersinia pseudotuberculosis YPIII]
gb|ACA69671.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Yersinia pseudotuberculosis YPIII]
Length = 547
Score = 871 bits (2252), Expect = 0.0, Method: Composition-based stats.
Identities = 331/544 (60%), Positives = 419/544 (77%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY LV+ +VSV +ILKVE LTLLA +A D
Sbjct: 1 MSNKPFHYQDPFP-LKEDDTEYYLVSDKHVSVAQFEGH--DILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G K
Sbjct: 58 ASFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIMGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G E
Sbjct: 118 GQRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGEE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F FV KGGGSANK +L+QETK++L P L+ FL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLFVTKGGGSANKTYLYQETKALLTPGRLKAFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD +EQ +++ +++G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDTALEQELLEAAQDLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE +
Sbjct: 297 DVRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-HSTE 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK
Sbjct: 356 GQVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKI+VE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIDVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|YP_001335207.1| fumarase B (fumarate hydratase class I), anaerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
gb|ABR76977.1| fumarase B (fumarate hydratase class I), anaerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
Length = 550
Score = 871 bits (2251), Expect = 0.0, Method: Composition-based stats.
Identities = 333/544 (61%), Positives = 418/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L H DTEY L++K++VSV ++LKVE LTLLA +A D
Sbjct: 1 MSTKPFVYQDPFP-LAHDDTEYYLLSKEHVSVAEFDG--QQVLKVEPQALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LR SH + SI DPEASDND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 AAFMLRVSHQQQVASILLDPEASDNDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIMGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL++GV++ YT NLRYSQN PL MY E NTG NLPAQIDLY+ G E
Sbjct: 118 GQRVWTGGGDEAALAQGVYNTYTEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYSVDGEE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK+++ P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCMAKGGGSANKTYLYQETKALITPAKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS +Y D LPT+ +E G +RD+++EQ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AEATLKTVKLASTRYYDGLPTEGNE-HGQAFRDVQLEQELLQEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCPIG+GVSCSADR AKIN+DGIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPIGMGVSCSADRNIKAKINRDGIWIEKLESNPGKYIPEHLRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V I+LN PM +I A+LS HPV TRLSL GTIIVARDIAHA+++E+++N + LP Y+K
Sbjct: 356 GEVVSINLNQPMSEILAQLSAHPVSTRLSLNGTIIVARDIAHAKLKELIDNGEALPQYVK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P ASGS GPTTAGRMD +VDL Q++G S VMLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPAGYASGSLGPTTAGRMDSYVDLLQSHGASMVMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKSLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|YP_001480245.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Serratia proteamaculans 568]
gb|ABV43117.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Serratia proteamaculans 568]
Length = 548
Score = 870 bits (2250), Expect = 0.0, Method: Composition-based stats.
Identities = 322/544 (59%), Positives = 414/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+++D+VSV E+LKV LTLLA A D
Sbjct: 1 MSNKPFHYQDPFP-LKKDDTEYYLLSRDHVSVSEFEG--QEVLKVAPEALTLLAQHAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I +DP+AS+ND++VALQ ++N+ IAA ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILKDPDASENDKYVALQFLRNSEIAAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE ALSRGV++ + NLRYSQN L MY+E NTG NLPAQIDLY+ G E
Sbjct: 118 GQRVWTGGGDEAALSRGVYNTFIEDNLRYSQNAALDMYNEVNTGSNLPAQIDLYSVDGEE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L+P L+++L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLSPGKLKDYLVEKMRTLGTAACPPYHVAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD+ +E+ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AEATLKTVKLASTKYYDGLPTEGNE-HGQAFRDVALEEELLKEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RV+R+PRHGASCP+G+GVSCSADR KIN+DGIW+EKLE +P K++P+
Sbjct: 297 DIRVVRLPRHGASCPVGMGVSCSADRNIKGKINRDGIWLEKLEHNPGKFIPQELRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM I +LS+ PV TRLSL+GTIIV RDIAHA+++E L+N + LP Y+K
Sbjct: 356 GEAVKIDLNRPMADILKQLSQFPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYVK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P+ ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPDGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ + ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKSLTCVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
Q+++
Sbjct: 536 QKIQ 539
>ref|YP_001402228.1| fumarate hydratase, class I [Yersinia pseudotuberculosis IP 31758]
gb|ABS49480.1| fumarate hydratase, class I [Yersinia pseudotuberculosis IP 31758]
Length = 547
Score = 870 bits (2250), Expect = 0.0, Method: Composition-based stats.
Identities = 333/544 (61%), Positives = 419/544 (77%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY LV+ +VSV +ILKVE LTLLA +A D
Sbjct: 1 MSNKPFHYQDPFP-LKEDDTEYYLVSDKHVSVAQFEGH--DILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G K
Sbjct: 58 ASFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIMGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G E
Sbjct: 118 GQRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGEE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F FV KGGGSANK +L+QETK++L P L+ FL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLFVTKGGGSANKTYLYQETKALLTPGRLKAFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD +EQ +++ +++G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDTALEQELLEAAQDLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RV+R+PRHGASCPIG+GVSCSADR KIN+ GIW+EKLE +P KY+PE +
Sbjct: 297 DVRVVRLPRHGASCPIGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-HSTE 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK
Sbjct: 356 GQVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|ZP_00822736.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Yersinia bercovieri ATCC
43970]
Length = 547
Score = 869 bits (2247), Expect = 0.0, Method: Composition-based stats.
Identities = 330/544 (60%), Positives = 421/544 (77%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY LV+ ++VSV ++LKVE LTLLA A D
Sbjct: 1 MSNKPFHYQDPFP-LTEDDTEYYLVSNNHVSVAQFEGH--DMLKVEPEALTLLAQHAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G K
Sbjct: 58 ASFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +
Sbjct: 118 GQRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGED 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F FV KGGGSANK +L+QETK++L+P L+ +L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLFVTKGGGSANKTYLYQETKALLSPGKLKEYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD+ +EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDIALEQELLEAAQELGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE Q +
Sbjct: 297 DVRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-QSNE 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK
Sbjct: 356 GKVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEDLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|YP_001005156.1| fumarate hydratase, class I [Yersinia enterocolitica subsp.
enterocolitica 8081]
emb|CAL10918.1| fumarate hydratase, class I [Yersinia enterocolitica subsp.
enterocolitica 8081]
Length = 547
Score = 869 bits (2246), Expect = 0.0, Method: Composition-based stats.
Identities = 330/544 (60%), Positives = 422/544 (77%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY LV+ ++VSV ++LKVE LTLLA A D
Sbjct: 1 MSNKPFHYQDPFP-LKEDDTEYYLVSNNHVSVAQFEGH--DMLKVEPEALTLLAQHAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G K
Sbjct: 58 ASFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +
Sbjct: 118 GQRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYQEVNTGTNLPAQIDLYSTEGED 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F FV KGGGSANK +L+QETK++L+P L+++L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLFVTKGGGSANKTYLYQETKALLSPGKLKDYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD+++EQ +++ +++G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDIQLEQELLEAAQDLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE +
Sbjct: 297 DVRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-HSTE 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM I ELS++PV TRLSLTGTIIV RDIAHA+++E L+N + LP YIK
Sbjct: 356 GKVVKIDLNRPMADILKELSQYPVSTRLSLTGTIIVGRDIAHAKLKERLDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|YP_001177280.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Enterobacter sp. 638]
gb|ABP61229.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit
[Enterobacter sp. 638]
Length = 549
Score = 869 bits (2246), Expect = 0.0, Method: Composition-based stats.
Identities = 330/544 (60%), Positives = 423/544 (77%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L H DT+Y L+TK++VSVV EILKVE LTLLA +A D
Sbjct: 1 MSNKPFYYQNPFP-LEHDDTDYYLLTKEHVSVVEFAG--QEILKVEPEALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRPSH + +I DP+AS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 AAFMLRPSHQKQVAAILHDPDASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIMGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE ALS+GV++ Y NLRYSQN L MY E NTG NLPAQIDLY+ G E
Sbjct: 118 GQRVWTGGGDEAALSQGVYNTYIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK+++ P L+N+L +K+ ++GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCMAKGGGSANKTYLYQETKALITPAKLKNYLVDKMRSLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS +Y D LPT+ +E G +RD+++EQ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTRYYDGLPTEGNE-HGQAFRDVQLEQELLQEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +PA+Y+PE +Q
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLEHNPAQYIPESLREQGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V I+LN PM++I A+L+ HPV TRLSL GTIIVARD+AHA+++E+++N + LP Y+K
Sbjct: 356 GDVVSINLNSPMNEILAQLTAHPVSTRLSLNGTIIVARDMAHAKLKELIDNGEELPQYVK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++G S VMLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGASMVMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ +E + ELGMEA+WKIEVENFPAFI+ DDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQNSIKSLECVAYPELGMEAIWKIEVENFPAFILADDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|ZP_02561418.1| fumarase B [Salmonella enterica subsp. enterica serovar Kentucky
str. CVM29188]
ref|ZP_02656375.1| fumarase B [Salmonella enterica subsp. enterica serovar Kentucky
str. CDC 191]
Length = 548
Score = 868 bits (2244), Expect = 0.0, Method: Composition-based stats.
Identities = 331/543 (60%), Positives = 407/543 (74%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S F + P + TEY L+T DYVSV IL VE LTLLA +A D
Sbjct: 1 MSKKEFIYQAPFP-MGEDKTEYYLLTSDYVSVSEFNG--ESILNVEPQALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP H + +I DPEAS+ND++VALQ ++N+ IAA ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPEHQQQVAAILHDPEASENDKYVALQFLRNSEIAAKGILPTCQDTGTAIIMGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE ALS+GV + Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEAALSKGVFNTYIEDNLRYSQNAPLDMYKEVNTGSNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS Y D LPT+ +E G +RDL +EQ ++ +G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTHYYDALPTEGNE-HGQAFRDLRLEQELLKEAHKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPPALRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E +E+ + LP YIK
Sbjct: 356 GDAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKERIESGEDLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|YP_001335177.1| fumarase A (fumarate hydratase class I), aerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
gb|ABR76947.1| fumarase A (fumarate hydratase class I), aerobic isozyme
[Klebsiella pneumoniae subsp. pneumoniae MGH 78578]
Length = 548
Score = 868 bits (2243), Expect = 0.0, Method: Composition-based stats.
Identities = 332/544 (61%), Positives = 420/544 (77%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L++ DYVSV E+LKV+ LTLLA A D
Sbjct: 1 MSNKPFVYQDPFP-LKKDDTEYYLLSSDYVSVAEFAG--QEVLKVDPQALTLLAQHAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILNDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIMGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL++GV++ Y NLRYSQN PL MY E NTG NLPAQIDLYAT G E
Sbjct: 118 GQRVWTGGGDEAALAQGVYNTYIQDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYATDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK+++ P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALITPAKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD++MEQ ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AEATLKTVKLASTKYYDGLPTEGNE-HGQAFRDVQMEQELLLEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN+DGIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRDGIWIEKLESNPGKYIPEHLRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK++LN PM +I A+LS++PV TRLSL+GTIIVARDIAHA+++E+++N + LP Y+K
Sbjct: 356 GEAVKVNLNQPMSEILAQLSQYPVSTRLSLSGTIIVARDIAHAKLKELIDNGEALPQYVK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P+ ASGS GPTTAGRMD +VDL Q++G S +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPDGYASGSLGPTTAGRMDSYVDLLQSHGASKIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E + ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKSLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|ZP_00835117.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Yersinia intermedia ATCC
29909]
Length = 547
Score = 867 bits (2241), Expect = 0.0, Method: Composition-based stats.
Identities = 327/544 (60%), Positives = 420/544 (77%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY LV+ ++VSV ++LKVE LTLLA A D
Sbjct: 1 MSNKPFHYQDPFP-LKEDDTEYYLVSNNHVSVTQFEGH--DMLKVEPEALTLLAQHAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G K
Sbjct: 58 ASFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G+D +ALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +
Sbjct: 118 GQRVWTGGNDAQALSRGVYNTFIEDNLRYSQNAALDMYQEVNTGTNLPAQIDLYSTEGED 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F FV KGGGSANK +L+QETK++L+P L+ +L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLFVTKGGGSANKTYLYQETKALLSPGKLKEYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD +EQ +++ +++G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDTALEQELLEAAQDLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+E+LE +P +Y+PE Q +
Sbjct: 297 DVRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLERLEQNPGQYIPEHLR-QSTE 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK
Sbjct: 356 GKVVKIDLNRPMADILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|ZP_02685331.1| fumarase B [Salmonella enterica subsp. enterica serovar Hadar str.
RI_05P066]
Length = 548
Score = 867 bits (2241), Expect = 0.0, Method: Composition-based stats.
Identities = 328/543 (60%), Positives = 407/543 (74%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S F + P + TEY L+T DYVSV IL VE LTLLA +A D
Sbjct: 1 MSKKEFIYQAPFP-MGEDKTEYYLLTSDYVSVSEFNG--ESILNVEPQALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP H + +I DPEAS+ND++VALQ ++N+ IAA +LP CQDTGTAII G K
Sbjct: 58 ASFMLRPEHQQQVAAILHDPEASENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIMGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE ALS+GV + Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEAALSKGVFNTYIEDNLRYSQNAPLDMYKEVNTGSNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS Y D LP + +E G +RD +EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTHYYDALPAEGNE-HGQAFRDPHLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPPALRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E +E+ + LP YIK
Sbjct: 356 GDAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKERIESGEDLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|ZP_03833166.1| fumarate hydratase class I, aerobic [Pectobacterium carotovorum
subsp. carotovorum WPP14]
Length = 547
Score = 866 bits (2240), Expect = 0.0, Method: Composition-based stats.
Identities = 328/544 (60%), Positives = 417/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L++ D+VSV +ILK+E A LTLLA +A D
Sbjct: 1 MSNKPFYYQDPFP-LSKDDTEYRLLSSDFVSVAQFEG--QDILKIEPAALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILHDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G+ V+T G+D EALS+GV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +
Sbjct: 118 GQNVWTGGNDAEALSKGVYNTFVEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGED 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F FV KGGGSANK +L+QETK++L P L++FL EK+ ++GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLFVTKGGGSANKTYLYQETKALLTPGKLKSFLIEKMRSLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY DELPT+ +E G +RD+ +EQ +++ R++G+GAQFGGKYFAH
Sbjct: 238 AETTLKTVKLASTKYYDELPTEGNE-HGQAFRDVALEQEILEAARDLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D R+IR+PRHGASCP+G+GVSCSADR KIN+ G+W+E+LE +P KY+PE +
Sbjct: 297 DVRIIRLPRHGASCPVGMGVSCSADRNIKGKINRKGVWLEQLEQNPGKYIPEHLRETGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM +I LS++PV TRLSLTGTIIV RDIAHA+++E L+N + LP YIK
Sbjct: 356 GDAVKIDLNRPMAEILKTLSQYPVSTRLSLTGTIIVGRDIAHAKLKERLDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE SGS GPTTAGRMD +VDL QANGGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYPSGSLGPTTAGRMDSYVDLLQANGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ + ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAILAQNSIKSLTCVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
Q ++
Sbjct: 536 QVIQ 539
>ref|ZP_00831475.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Yersinia frederiksenii ATCC
33641]
Length = 547
Score = 866 bits (2239), Expect = 0.0, Method: Composition-based stats.
Identities = 329/544 (60%), Positives = 423/544 (77%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY LV+ ++VSV +ILKVE LTLLA A D
Sbjct: 1 MSNKPFHYQDPFP-LKEDDTEYYLVSNNHVSVAQFEGH--DILKVEPEALTLLAQHAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I +DP+AS+ND++VALQ ++N+ I+A ILP CQDTGTAII G K
Sbjct: 58 ASFLLRPAHQKQVAAILDDPQASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +
Sbjct: 118 GQRVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGED 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F FV KGGGSANK +L+QETK++L+P L+++L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLFVTKGGGSANKTYLYQETKALLSPGKLKDYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD+++EQ +++ +++G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDIQLEQELLEAAQDLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE +
Sbjct: 297 DVRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-HSTE 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK
Sbjct: 356 GKVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|NP_463165.1| fumarase B [Salmonella typhimurium LT2]
ref|ZP_02572611.1| fumarase B [Salmonella enterica subsp. enterica serovar
4,[5],12:i:- str. CVM23701]
gb|AAL23124.1| fumarase B [Salmonella typhimurium LT2]
Length = 548
Score = 866 bits (2238), Expect = 0.0, Method: Composition-based stats.
Identities = 329/543 (60%), Positives = 407/543 (74%), Gaps = 5/543 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S F + P + TEY L+T DYVSV IL VE LTLLA +A D
Sbjct: 1 MSKKEFIYQAPFP-MGEDKTEYYLLTSDYVSVSEFNG--ESILNVEPQALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP H + +I DPEAS+ND++VALQ ++N+ IAA ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPEHQQQVAAILHDPEASENDKYVALQFLRNSEIAAKGILPTCQDTGTAIIMGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE ALS+GV + Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEAALSKGVFNTYIEDNLRYSQNAPLNMYKEVNTGSNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F VAKGGGSANK +L+QETK++L P L+NFL EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS Y D LP + +E G +RD +EQ +++ + +G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTHYYDALPAEGNE-HGQAFRDPHLEQELLEEAQKLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCP+G+GVSCSADR AKIN++GIW+EKLE +P +Y+P
Sbjct: 297 DIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIWIEKLEHNPGQYIPPALRQAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VK+DLN PM +I A+LS++PV TRLSLTGTIIV RDIAHA+++E +E+ + LP YIK
Sbjct: 356 GDAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKLKERIESGEDLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK P SGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQQSIKHLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQL 554
QQ+
Sbjct: 536 QQI 538
>ref|YP_049013.1| fumarate hydratase class I, aerobic [Erwinia carotovora subsp.
atroseptica SCRI1043]
emb|CAG73816.1| fumarate hydratase class I, aerobic [Erwinia carotovora subsp.
atroseptica SCRI1043]
Length = 547
Score = 865 bits (2237), Expect = 0.0, Method: Composition-based stats.
Identities = 329/544 (60%), Positives = 416/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L++ D+VSV +ILKVE A LTLLA +A D
Sbjct: 1 MSNKPFYYQDPFP-LSKDDTEYRLLSSDFVSVAQFEG--QDILKVEPAALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILHDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G+ V+T G+D EALS+GV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +
Sbjct: 118 GQNVWTGGNDAEALSQGVYNTFIEDNLRYSQNAALDMYQEVNTGTNLPAQIDLYSTEGED 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F FV KGGGSANK +L+QETK++L P L++FL EK+ ++GT+ACPPYH+A +GGTS
Sbjct: 178 YKFLFVTKGGGSANKTYLYQETKALLTPGKLKSFLIEKMRSLGTAACPPYHIAFAIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY DELPT+ +E G +RD+ +EQ +++ R++G+GAQFGGKYFAH
Sbjct: 238 AETTLKTVKLASTKYYDELPTEGNE-HGQAFRDVALEQEILEAARDLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D R+IR+PRHGASCP+G+GVSCSADR KIN+ G+W+E+LE +P KY+PE +
Sbjct: 297 DVRIIRLPRHGASCPVGMGVSCSADRNIKGKINRKGVWLEQLEQNPGKYIPEHLRETGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM +I LS++PV TRLSLTGTIIV RDIAHA+++E L+N + LP YIK
Sbjct: 356 GDAVKIDLNRPMTEILKTLSQYPVSTRLSLTGTIIVGRDIAHAKLKERLDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE SGS GPTTAGRMD +VDL QANGGS VMLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYPSGSLGPTTAGRMDSYVDLLQANGGSMVMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ + ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAILAQNSIKSLTCVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
Q ++
Sbjct: 536 QVIQ 539
>ref|ZP_03828861.1| fumarate hydratase class I, aerobic [Pectobacterium carotovorum
subsp. brasiliensis PBR1692]
Length = 547
Score = 865 bits (2237), Expect = 0.0, Method: Composition-based stats.
Identities = 328/544 (60%), Positives = 417/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L++ D+VSV +ILK+E A LTLLA +A D
Sbjct: 1 MSNKPFYYQDPFP-LSKDDTEYRLLSSDFVSVAQFEG--QDILKIEPAALTLLAQQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILSDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G+ V+T G+D EALS+GV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +
Sbjct: 118 GQNVWTGGNDAEALSQGVYNTFIEDNLRYSQNAALDMYKEVNTGTNLPAQIDLYSTEGED 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F FV KGGGSANK +L+QETK++L P L++FL EK+ ++GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLFVTKGGGSANKTYLYQETKALLTPGKLKSFLIEKMRSLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY DELPT+ +E G +RD+ +EQ +++ R++G+GAQFGGKYFAH
Sbjct: 238 AETTLKTVKLASTKYYDELPTEGNE-HGQAFRDVALEQEILEAARDLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D R+IR+PRHGASCP+G+GVSCSADR KIN+ G+W+E+LE +P KY+PE +
Sbjct: 297 DVRIIRLPRHGASCPVGMGVSCSADRNIKGKINRKGVWLEQLEQNPGKYIPEHLRETGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM +I LS++PV TRLSLTGTIIV RDIAHA+++E L+N + LP YIK
Sbjct: 356 GDAVKIDLNRPMAEILKTLSQYPVSTRLSLTGTIIVGRDIAHAKLKERLDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE SGS GPTTAGRMD +VDL QANGGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYPSGSLGPTTAGRMDSYVDLLQANGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ + ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAILAQNSIKSLTCVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
Q ++
Sbjct: 536 QVIQ 539
>ref|ZP_02903194.1| fumarate hydratase [Escherichia albertii TW07627]
gb|EDS91220.1| fumarate hydratase [Escherichia albertii TW07627]
Length = 548
Score = 865 bits (2235), Expect = 0.0, Method: Composition-based stats.
Identities = 334/544 (61%), Positives = 415/544 (76%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY L+T ++VSV E+LKV LTLLA +A D
Sbjct: 1 MSNKPFHYQAPFP-LKKDDTEYYLLTSEHVSVSEFEG--QEVLKVAPEALTLLARQAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + I DPEAS+ND++VALQ ++N++IAA ILP CQDTGTAII G K
Sbjct: 58 ASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G++V+T G DE AL+RGV++ Y NLRYSQN PL MY E NTG NLPAQIDLYA G E
Sbjct: 118 GQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNTGTNLPAQIDLYAVDGDE 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F +AKGGGSANK +L+QETK++L P L+N+L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE +K VK AS KY DELPT+ +E G +RD+E+E ++ +N+G+GAQFGGKYFAH
Sbjct: 238 AETNLKTVKLASAKYYDELPTEGNE-HGQAFRDVELENELLLEAQNLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RVIR+PRHGASCPIG+GVSCSADR AKIN+ GIW+EKLE +P KY+PE
Sbjct: 297 DIRVIRLPRHGASCPIGMGVSCSADRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAGE- 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
V++DLN PM +I A+LS++PV TRLSL GTIIV RDIAHA+++E ++N + LP YIK
Sbjct: 356 GEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKLKERMDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VD QA GGS +MLAKGNRS++VT+ACK
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQAQGGSMIMLAKGNRSQQVTDACK 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
>ref|ZP_00825174.1| COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase
class I, N-terminal domain [Yersinia mollaretii ATCC
43969]
Length = 547
Score = 865 bits (2235), Expect = 0.0, Method: Composition-based stats.
Identities = 331/544 (60%), Positives = 421/544 (77%), Gaps = 5/544 (0%)
Query: 12 KSAPPFKFVPLLPHLHHKDTEYTLVTKDYVSVVNPGAGLPEILKVEAAGLTLLASRAIGD 71
S PF + P L DTEY LV+ ++VSV +ILKVE LTLLA A D
Sbjct: 1 MSNKPFHYQDPFP-LKEDDTEYYLVSNNHVSVAQFEGH--DILKVEPEALTLLAQHAFHD 57
Query: 72 VQHFLRPSHLASLRSIFEDPEASDNDRFVALQLIKNANIAAARILPGCQDTGTAIIAGYK 131
LRP+H + +I +DPEAS+ND++VALQ ++N+ I+A ILP CQDTGTAII G K
Sbjct: 58 ASFLLRPAHQKQVAAILDDPEASENDKYVALQFLRNSEISAKGILPTCQDTGTAIIVGKK 117
Query: 132 GEQVFTNGDDEEALSRGVHHIYTTTNLRYSQNVPLTMYDEKNTGCNLPAQIDLYATKGCE 191
G+ V+T G+D EALSRGV++ + NLRYSQN L MY E NTG NLPAQIDLY+T+G +
Sbjct: 118 GQCVWTGGNDAEALSRGVYNTFIEDNLRYSQNAALDMYREVNTGTNLPAQIDLYSTEGED 177
Query: 192 YEFFFVAKGGGSANKAFLFQETKSVLNPKSLRNFLEEKISTIGTSACPPYHMAVVVGGTS 251
Y+F FV KGGGSANK +L+QETK++L+P L+ +L EK+ T+GT+ACPPYH+A V+GGTS
Sbjct: 178 YKFLFVTKGGGSANKTYLYQETKALLSPGKLKEYLVEKMRTLGTAACPPYHIAFVIGGTS 237
Query: 252 AEMTMKAVKYASCKYLDELPTKPDESKGYTYRDLEMEQMVMDICRNIGMGAQFGGKYFAH 311
AE T+K VK AS KY D LPT+ +E G +RD+ +EQ +++ +++G+GAQFGGKYFAH
Sbjct: 238 AESTLKTVKLASTKYYDGLPTEGNE-HGQAFRDIALEQELLEAAQDLGLGAQFGGKYFAH 296
Query: 312 DARVIRMPRHGASCPIGIGVSCSADRQALAKINKDGIWVEKLEMDPAKYLPEVTEDQLLK 371
D RV+R+PRHGASCP+G+GVSCSADR KIN+ GIW+EKLE +P KY+PE Q +
Sbjct: 297 DVRVVRLPRHGASCPVGMGVSCSADRNIKGKINRKGIWLEKLEQNPGKYIPEHLR-QSNE 355
Query: 372 VPPVKIDLNMPMDKIRAELSRHPVKTRLSLTGTIIVARDIAHARMREMLENNKPLPDYIK 431
VKIDLN PM +I ELS++PV TRLSL+GTIIV RDIAHA+++E L+N + LP YIK
Sbjct: 356 GKVVKIDLNRPMPEILKELSQYPVSTRLSLSGTIIVGRDIAHAKLKERLDNGEGLPQYIK 415
Query: 432 NHPVYYAGPAKRPEALASGSFGPTTAGRMDPFVDLFQANGGSFVMLAKGNRSKRVTEACK 491
+HP+YYAGPAK PE ASGS GPTTAGRMD +VDL Q++GGS +MLAKGNRS++VT+AC
Sbjct: 416 DHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACH 475
Query: 492 KYGGFYLGSIGGPAALLAMDSIRKVEVLDMEELGMEAVWKIEVENFPAFIVVDDKGNDFF 551
K+GGFYLGSIGGPAA+LA +SI+ +E ++ ELGMEA+WKIEVE+FPAFI+VDDKGNDFF
Sbjct: 476 KHGGFYLGSIGGPAAVLAQNSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFF 535
Query: 552 QQLR 555
QQ++
Sbjct: 536 QQIQ 539
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.314 0.191 0.603
Lambda K H
0.267 0.0586 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,191,189,733
Number of Sequences: 6899187
Number of extensions: 723943800
Number of successful extensions: 1538782
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 2459
Number of HSP's successfully gapped in prelim test: 306
Number of HSP's that attempted gapping in prelim test: 1522491
Number of HSP's gapped (non-prelim): 2900
length of query: 555
length of database: 2,350,152,223
effective HSP length: 139
effective length of query: 416
effective length of database: 1,391,165,230
effective search space: 578724735680
effective search space used: 578724735680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 83 (36.1 bits)