BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= ENSG00000120915__[Homo_sapiens]
(555 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_001970.2| epoxide hydrolase 2, cytoplasmic [Homo sap... 1160 0.0
gb|AAP36260.1| Homo sapiens epoxide hydrolase 2, cytoplasmi... 1160 0.0
gb|AAG14967.1|AF233335_1 soluble epoxide hydrolase [Homo sa... 1158 0.0
gb|AAG14968.1|AF233336_1 soluble epoxide hydrolase [Homo sa... 1155 0.0
ref|XP_001163779.1| PREDICTED: epoxide hydrolase 2, cytopla... 1152 0.0
gb|AAA02756.1| cytosolic epoxide hydrolase 1149 0.0
gb|EAW63547.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 1148 0.0
ref|XP_001163896.1| PREDICTED: epoxide hydrolase 2, cytopla... 1136 0.0
ref|XP_001109474.1| PREDICTED: similar to epoxide hydrolase... 1094 0.0
ref|XP_001163861.1| PREDICTED: epoxide hydrolase 2, cytopla... 1063 0.0
gb|EAW63549.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 1055 0.0
ref|XP_001163819.1| PREDICTED: epoxide hydrolase 2, cytopla... 1050 0.0
ref|XP_001163527.1| PREDICTED: epoxide hydrolase 2, cytopla... 1046 0.0
gb|EAW63551.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 1029 0.0
ref|XP_001163565.1| PREDICTED: epoxide hydrolase 2, cytopla... 1020 0.0
ref|XP_001492725.1| PREDICTED: similar to soluble epoxide h... 940 0.0
ref|XP_534566.1| PREDICTED: similar to epoxide hydrolase 2,... 940 0.0
ref|XP_857471.1| PREDICTED: similar to epoxide hydrolase 2,... 939 0.0
ref|NP_001001641.1| soluble epoxide hydrolase [Sus scrofa] ... 938 0.0
ref|XP_857554.1| PREDICTED: similar to epoxide hydrolase 2,... 928 0.0
ref|XP_857430.1| PREDICTED: similar to epoxide hydrolase 2,... 920 0.0
ref|NP_001069002.1| epoxide hydrolase 2, cytoplasmic [Bos t... 911 0.0
emb|CAA85471.1| Epoxide Hydrolase [Mus musculus] 883 0.0
ref|NP_031966.2| epoxide hydrolase 2, cytoplasmic [Mus musc... 881 0.0
dbj|BAE25172.1| unnamed protein product [Mus musculus] 880 0.0
ref|NP_075225.1| epoxide hydrolase 2, cytoplasmic [Rattus n... 874 0.0
gb|AAH85732.1| Epoxide hydrolase 2, cytoplasmic [Rattus nor... 870 0.0
gb|EDL36006.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 822 0.0
gb|EDL85377.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 816 0.0
gb|AAM28238.1| ovary-selective epoxide hydrolase [Mus muscu... 813 0.0
gb|ABU95055.1| epoxide hydrolase 2C [Mus musculus] 800 0.0
ref|XP_001380051.1| PREDICTED: similar to soluble epoxide h... 729 0.0
ref|NP_001006912.1| epoxide hydrolase 2, cytoplasmic [Xenop... 684 0.0
ref|NP_001028817.1| epoxide hydrolase 2, cytoplasmic [Gallu... 682 0.0
ref|NP_001087143.1| epoxide hydrolase 2, cytoplasmic [Xenop... 676 0.0
emb|CAH91370.1| hypothetical protein [Pongo abelii] 654 0.0
ref|XP_001521600.1| PREDICTED: similar to epoxide hydrolase... 617 e-175
ref|NP_001008642.1| epoxide hydrolase 2, cytoplasmic [Danio... 574 e-162
gb|ACC95977.1| soluble epoxide hydrolase-like protein 1 [St... 486 e-135
emb|CAG00866.1| unnamed protein product [Tetraodon nigrovir... 480 e-133
gb|EAW63550.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 471 e-131
ref|XP_795168.2| PREDICTED: similar to Ephx2-prov protein [... 459 e-127
ref|XP_001184789.1| PREDICTED: similar to Ephx2-prov protei... 458 e-127
ref|XP_795076.2| PREDICTED: similar to Ephx2-prov protein, ... 425 e-117
ref|XP_001190554.1| PREDICTED: similar to Ephx2-prov protei... 423 e-116
ref|XP_001641873.1| predicted protein [Nematostella vectens... 403 e-110
gb|ACC95978.1| soluble epoxide hydrolase-like protein 2 [St... 328 8e-88
ref|XP_001253507.1| PREDICTED: hypothetical protein [Bos ta... 290 2e-76
ref|XP_001181957.1| PREDICTED: similar to soluble epoxide h... 266 4e-69
ref|YP_486290.1| Alpha/beta hydrolase [Rhodopseudomonas pal... 239 6e-61
ref|YP_001413763.1| alpha/beta hydrolase fold [Parvibaculum... 237 2e-60
ref|YP_001683228.1| alpha/beta hydrolase fold [Caulobacter ... 234 1e-59
ref|NP_767754.1| epoxide hydrolase [Bradyrhizobium japonicu... 234 1e-59
ref|NP_420043.1| epoxide hydrolase [Caulobacter crescentus ... 234 2e-59
ref|YP_569843.1| alpha/beta hydrolase fold [Rhodopseudomona... 225 7e-57
gb|EDL85378.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 223 4e-56
ref|YP_761108.1| putative epoxide hydrolase [Hyphomonas nep... 222 5e-56
ref|NP_771160.1| epoxide hydrolase [Bradyrhizobium japonicu... 222 8e-56
ref|ZP_02299346.1| alpha/beta hydrolase fold [Rhodopseudomo... 220 2e-55
ref|NP_218134.1| PROBABLE EPOXIDE HYDROLASE EPHA (EPOXIDE H... 220 3e-55
ref|YP_001853373.1| epoxide hydrolase EphA [Mycobacterium m... 219 4e-55
ref|NP_821315.1| epoxide hydrolase [Streptomyces avermitili... 219 4e-55
ref|YP_907699.1| epoxide hydrolase EphA [Mycobacterium ulce... 219 4e-55
ref|YP_629896.1| putative epoxide hydrolase [Myxococcus xan... 219 4e-55
ref|NP_948116.1| epoxide hydrolase [Rhodopseudomonas palust... 218 1e-54
ref|YP_001310928.1| alpha/beta hydrolase fold [Clostridium ... 217 2e-54
ref|ZP_01717897.1| probable ephA protein-Mycobacterium tube... 217 2e-54
ref|YP_001240076.1| Putative epoxide hydrolase [Bradyrhizob... 216 3e-54
ref|ZP_00877473.1| COG0596: Predicted hydrolases or acyltra... 214 1e-53
ref|NP_354796.1| epoxide hydrolase [Agrobacterium tumefacie... 212 5e-53
ref|NP_959380.1| EphA [Mycobacterium avium subsp. paratuber... 212 5e-53
ref|YP_001701281.1| Probable epoxide hydrolase EphA [Mycoba... 212 7e-53
ref|YP_879819.1| hydrolase, alpha/beta fold family protein ... 211 2e-52
ref|NP_627771.1| epoxide hydrolase [Streptomyces coelicolor... 210 3e-52
ref|NP_356953.2| epoxide hydrolase [Agrobacterium tumefacie... 209 5e-52
emb|CAG44464.1| putative epoxide hydrolase [Streptomyces ri... 209 5e-52
gb|EEJ94100.1| predicted hydrolase or acyltransferase of al... 208 8e-52
ref|YP_692156.1| hydrolase, alpha/beta fold family [Alcaniv... 206 3e-51
gb|ABK21215.1| unknown [Picea sitchensis] 206 3e-51
ref|YP_001238893.1| putative epoxide hydrolase [Bradyrhizob... 205 7e-51
ref|ZP_01864318.1| putative epoxide hydrolase [Erythrobacte... 205 7e-51
emb|CAO44814.1| unnamed protein product [Vitis vinifera] 205 9e-51
ref|YP_002769440.1| epoxide hydrolase [Rhodococcus erythrop... 205 1e-50
ref|YP_002767073.1| epoxide hydrolase [Rhodococcus erythrop... 204 2e-50
ref|YP_260055.1| ephA [Pseudomonas fluorescens Pf-5] >gi|68... 204 2e-50
ref|YP_001204572.1| putative epoxide hydrolase [Bradyrhizob... 203 3e-50
ref|YP_001205815.1| epoxide hydrolase [Bradyrhizobium sp. O... 202 5e-50
ref|YP_781780.1| alpha/beta hydrolase fold [Rhodopseudomona... 202 7e-50
ref|ZP_01618404.1| epoxide hydrolase [marine gamma proteoba... 201 2e-49
dbj|BAD13534.1| soluble epoxide hydrolase [Citrus jambhiri] 200 3e-49
gb|ABL97491.1| putative epoxide hydrolase [uncultured marin... 200 3e-49
ref|YP_568956.1| alpha/beta hydrolase fold [Rhodopseudomona... 200 3e-49
ref|YP_703564.1| probable epoxide hydrolase [Rhodococcus sp... 199 6e-49
ref|YP_001890397.1| alpha/beta hydrolase fold [Burkholderia... 198 8e-49
ref|ZP_01690851.1| epoxide hydrolase 2 [Microscilla marina ... 198 8e-49
ref|NP_769521.1| epoxide hydrolase [Bradyrhizobium japonicu... 198 9e-49
gb|ACO95125.1| epoxide hydrolase [uncultured organism] 197 3e-48
dbj|BAA09852.1| Epoxide hydrolase [Glycine max] >gi|2764804... 196 4e-48
ref|NP_823281.1| epoxide hydrolase [Streptomyces avermitili... 196 5e-48
emb|CAO44812.1| unnamed protein product [Vitis vinifera] 196 5e-48
ref|YP_001682147.1| alpha/beta hydrolase fold [Caulobacter ... 196 6e-48
gb|ABN08020.1| Epoxide hydrolase [Medicago truncatula] 195 8e-48
ref|YP_890327.1| epoxide hydrolase [Mycobacterium smegmatis... 195 8e-48
prf||1802277A epoxide hydrolase 195 8e-48
ref|YP_531536.1| alpha/beta hydrolase fold [Rhodopseudomona... 195 1e-47
ref|YP_611899.1| alpha/beta hydrolase fold [Silicibacter sp... 195 1e-47
emb|CAA55294.1| epoxide hydrolase [Glycine max] 194 1e-47
emb|CAN77654.1| hypothetical protein [Vitis vinifera] 194 1e-47
emb|CAO70601.1| unnamed protein product [Vitis vinifera] 194 2e-47
ref|YP_641931.1| alpha/beta hydrolase fold [Mycobacterium s... 193 3e-47
gb|ABL97724.1| epoxide hydrolase [uncultured marine bacteri... 193 3e-47
ref|YP_001073412.1| alpha/beta hydrolase fold [Mycobacteriu... 193 3e-47
ref|XP_001179361.1| PREDICTED: similar to soluble epoxide h... 193 3e-47
ref|NP_824987.1| epoxide hydrolase [Streptomyces avermitili... 193 3e-47
ref|YP_001132685.1| alpha/beta hydrolase fold [Mycobacteriu... 192 8e-47
ref|YP_002780595.1| epoxide hydrolase [Rhodococcus opacus B... 191 1e-46
ref|NP_866425.1| probable ephA protein-Mycobacterium tuberc... 191 1e-46
emb|CAA42898.1| cytosolic epoxide hydrolase [Rattus norvegi... 191 2e-46
ref|NP_567228.1| epoxide hydrolase, putative [Arabidopsis t... 191 2e-46
ref|YP_001545639.1| alpha/beta hydrolase fold [Herpetosipho... 190 2e-46
emb|CAO44811.1| unnamed protein product [Vitis vinifera] 190 3e-46
gb|AAM28292.1| epoxide hydrolase [Ananas comosus] 190 3e-46
ref|YP_586462.1| alpha/beta hydrolase fold [Ralstonia metal... 190 3e-46
ref|NP_190669.1| epoxide hydrolase, putative [Arabidopsis t... 188 1e-45
ref|YP_001828469.1| putative epoxide hydrolase [Streptomyce... 188 1e-45
gb|ABK93786.1| unknown [Populus trichocarpa] 188 1e-45
gb|ABN08024.1| Epoxide hydrolase [Medicago truncatula] 187 1e-45
ref|YP_001828370.1| putative epoxide hydrolase [Streptomyce... 187 3e-45
ref|XP_001753609.1| predicted protein [Physcomitrella paten... 186 5e-45
gb|ABN08021.1| Epoxide hydrolase [Medicago truncatula] 185 9e-45
ref|NP_187211.1| epoxide hydrolase, putative [Arabidopsis t... 184 1e-44
emb|CAO17500.1| unnamed protein product [Vitis vinifera] 184 1e-44
ref|YP_956150.1| alpha/beta hydrolase fold [Mycobacterium v... 184 1e-44
gb|EAY92418.1| hypothetical protein OsI_013651 [Oryza sativ... 184 2e-44
ref|YP_001704492.1| Probable epoxide hydrolase EphA [Mycoba... 184 2e-44
gb|EEH35520.1| epoxide hydrolase [Paracoccidioides brasilie... 183 4e-44
ref|ZP_01115718.1| probable ephA protein-Mycobacterium tube... 182 5e-44
ref|YP_001189322.1| alpha/beta hydrolase fold [Pseudomonas ... 182 6e-44
ref|ZP_01615162.1| EphA [marine gamma proteobacterium HTCC2... 181 1e-43
ref|XP_001239812.1| hypothetical protein CIMG_09433 [Coccid... 181 2e-43
emb|CAO40040.1| unnamed protein product [Vitis vinifera] 180 2e-43
gb|EEH44735.1| epoxide hydrolase [Paracoccidioides brasilie... 180 3e-43
ref|NP_001042621.1| Os01g0255000 [Oryza sativa (japonica cu... 180 3e-43
ref|NP_001051780.1| Os03g0829100 [Oryza sativa (japonica cu... 180 3e-43
ref|NP_001051781.1| Os03g0829200 [Oryza sativa (japonica cu... 179 7e-43
emb|CAD30841.1| soluble epoxide hydrolase [Brassica napus] 179 8e-43
ref|YP_758097.1| alpha/beta hydrolase fold [Maricaulis mari... 178 9e-43
ref|ZP_01617969.1| putative epoxide hydrolase [marine gamma... 178 1e-42
ref|YP_761430.1| putative epoxide hydrolase [Hyphomonas nep... 177 2e-42
gb|ABK94011.1| unknown [Populus trichocarpa] 177 2e-42
ref|YP_954781.1| alpha/beta hydrolase fold [Mycobacterium v... 177 2e-42
ref|XP_001275970.1| epoxide hydrolase [Aspergillus clavatus... 176 4e-42
ref|ZP_01014743.1| putative epoxide hydrolase [Rhodobactera... 175 1e-41
ref|YP_954785.1| alpha/beta hydrolase fold [Mycobacterium v... 174 2e-41
ref|YP_001851161.1| epoxide hydrolase EphB [Mycobacterium m... 174 2e-41
gb|AAO27849.1|AF482450_1 soluble epoxide hydrolase [Euphorb... 172 6e-41
ref|NP_001067364.1| Os12g0636400 [Oryza sativa (japonica cu... 171 1e-40
pdb|2E3J|A Chain A, The Crystal Structure Of Epoxide Hydrol... 171 2e-40
pdb|2ZJF|A Chain A, Crystal Structure Of Mycobacterium Tube... 171 2e-40
ref|NP_216454.1| PROBABLE EPOXIDE HYDROLASE EPHB (EPOXIDE H... 171 2e-40
ref|NP_001042622.1| Os01g0255100 [Oryza sativa (japonica cu... 171 2e-40
ref|ZP_00957271.1| epoxide hydrolase [Oceanicaulis alexandr... 170 3e-40
ref|XP_001585413.1| hypothetical protein SS1G_13652 [Sclero... 169 5e-40
ref|XP_001261159.1| epoxide hydrolase [Neosartorya fischeri... 169 8e-40
ref|NP_001055069.1| Os05g0273800 [Oryza sativa (japonica cu... 168 1e-39
ref|YP_906638.1| epoxide hydrolase EphB [Mycobacterium ulce... 168 1e-39
ref|YP_001859441.1| alpha/beta hydrolase fold protein [Burk... 167 2e-39
ref|NP_180242.1| ATSEH (Arabidopsis thaliana soluble epoxid... 166 4e-39
ref|XP_386920.1| hypothetical protein FG06744.1 [Gibberella... 166 4e-39
emb|CAJ19276.1| putative epoxide hydrolase [Solanum commers... 165 8e-39
pdb|2CJP|A Chain A, Structure Of Potato (Solanum Tuberosum)... 165 1e-38
ref|XP_001377064.1| PREDICTED: similar to abhydrolase domai... 164 2e-38
gb|AAA81890.1| epoxide hydrolase 164 2e-38
ref|XP_001098374.1| PREDICTED: similar to abhydrolase domai... 164 2e-38
gb|EAY92419.1| hypothetical protein OsI_013652 [Oryza sativ... 164 3e-38
gb|AAA81892.1| epoxide hydrolase 164 3e-38
emb|CAO48291.1| unnamed protein product [Vitis vinifera] 164 3e-38
ref|XP_001402257.1| hypothetical protein An04g09000 [Asperg... 163 4e-38
gb|AAA81891.1| epoxide hydrolase 163 4e-38
ref|XP_422345.2| PREDICTED: similar to Abhydrolase domain c... 162 5e-38
sp|Q8IUS5|ABHD7_HUMAN Abhydrolase domain-containing protein... 162 6e-38
ref|NP_001069323.2| abhydrolase domain containing 7 [Bos ta... 162 7e-38
gb|AAA81889.1| epoxide hydrolase 162 9e-38
ref|NP_775838.2| abhydrolase domain containing 7 [Homo sapi... 161 1e-37
dbj|BAC11230.1| unnamed protein product [Homo sapiens] 161 2e-37
ref|YP_001263793.1| alpha/beta hydrolase fold [Sphingomonas... 161 2e-37
ref|ZP_02940345.1| alpha/beta hydrolase fold [Cyanothece sp... 160 2e-37
gb|EDU42427.1| epoxide hydrolase [Pyrenophora tritici-repen... 160 2e-37
gb|AAA81893.1| epoxide hydrolase 160 3e-37
ref|NP_193331.3| epoxide hydrolase, putative [Arabidopsis t... 160 3e-37
ref|XP_359602.1| hypothetical protein MGG_05175 [Magnaporth... 160 3e-37
ref|XP_001803986.1| hypothetical protein SNOG_13782 [Phaeos... 160 4e-37
ref|XP_001557163.1| epoxide hydrolase [Botryotinia fuckelia... 159 4e-37
ref|XP_001152592.1| PREDICTED: abhydrolase domain containin... 159 5e-37
sp|Q6IE26|ABHD7_MOUSE Abhydrolase domain-containing protein... 159 6e-37
ref|NP_001001804.2| epoxide hydrolase-related [Mus musculus... 159 6e-37
gb|EDL20166.1| abhydrolase domain containing 7 [Mus musculus] 159 6e-37
gb|EEK01551.1| predicted hydrolase or acyltransferase of al... 159 7e-37
ref|YP_476608.1| hydrolase, alpha/beta fold family [Synecho... 158 1e-36
gb|EAZ11286.1| hypothetical protein OsJ_001111 [Oryza sativ... 158 1e-36
ref|XP_001475646.1| PREDICTED: similar to epoxide hydrolase... 158 1e-36
ref|YP_001803894.1| unknown [Cyanothece sp. ATCC 51142] >gi... 157 3e-36
ref|YP_444434.1| hydrolase, alpha/beta fold family, putativ... 157 3e-36
ref|XP_001876554.1| epoxide hydrolase [Laccaria bicolor S23... 157 3e-36
ref|YP_119793.1| putative hydrolase [Nocardia farcinica IFM... 157 3e-36
ref|XP_001837532.1| hypothetical protein CC1G_01444 [Coprin... 156 4e-36
gb|ACO95126.1| epoxide hydrolase [uncultured organism] 156 5e-36
emb|CAB46034.1| putative epoxide hydrolase [Arabidopsis tha... 155 7e-36
emb|CAO23958.1| unnamed protein product [Vitis vinifera] 155 8e-36
gb|EAY73347.1| hypothetical protein OsI_001194 [Oryza sativ... 155 9e-36
ref|XP_965606.1| hypothetical protein NCU02924 [Neurospora ... 155 9e-36
ref|ZP_00108314.1| COG0596: Predicted hydrolases or acyltra... 155 1e-35
ref|NP_180243.1| epoxide hydrolase, putative [Arabidopsis t... 155 1e-35
ref|YP_001515531.1| hydrolase, alpha/beta fold family [Acar... 154 3e-35
gb|AAB02006.1| epoxide hydrolase [Nicotiana tabacum] 154 3e-35
ref|XP_001824748.1| hypothetical protein [Aspergillus oryza... 154 3e-35
ref|XP_547281.2| PREDICTED: similar to abhydrolase domain c... 153 3e-35
ref|YP_473962.1| hydrolase, alpha/beta fold family [Synecho... 152 6e-35
emb|CAO16924.1| unnamed protein product [Vitis vinifera] 152 6e-35
gb|ABK24656.1| unknown [Picea sitchensis] 152 7e-35
ref|ZP_01621577.1| hypothetical protein L8106_23540 [Lyngby... 151 1e-34
ref|NP_001072430.1| hydrolase (3B446) [Xenopus tropicalis] ... 151 1e-34
ref|ZP_03874491.1| predicted hydrolase or acyltransferase o... 151 1e-34
emb|CAO23957.1| unnamed protein product [Vitis vinifera] 150 2e-34
ref|XP_369638.1| hypothetical protein MGG_05826 [Magnaporth... 150 3e-34
ref|YP_001432538.1| alpha/beta hydrolase fold [Roseiflexus ... 149 5e-34
ref|XP_001493089.1| PREDICTED: similar to abhydrolase domai... 149 8e-34
gb|EAZ29152.1| hypothetical protein OsJ_012635 [Oryza sativ... 148 1e-33
ref|YP_001543763.1| alpha/beta hydrolase fold [Herpetosipho... 148 1e-33
ref|YP_137702.1| epoxide hydrolase-related protein [Haloarc... 148 1e-33
ref|YP_001614793.1| putative hydrolase of unknown specifici... 146 4e-33
ref|YP_321204.1| Alpha/beta hydrolase fold [Anabaena variab... 146 4e-33
ref|XP_364758.1| hypothetical protein MGG_09603 [Magnaporth... 146 4e-33
emb|CAD31713.1| epoxide hydrolase [Cicer arietinum] 146 5e-33
ref|ZP_01629817.1| Alpha/beta hydrolase fold protein [Nodul... 145 6e-33
gb|EDU50401.1| epoxide hydrolase 2 [Pyrenophora tritici-rep... 145 1e-32
ref|ZP_01461444.1| epoxide hydrolase [Stigmatella aurantiac... 145 1e-32
ref|NP_001064967.1| Os10g0498300 [Oryza sativa (japonica cu... 145 1e-32
ref|XP_694838.2| PREDICTED: hypothetical protein [Danio rerio] 145 1e-32
ref|XP_001822366.1| hypothetical protein [Aspergillus oryza... 145 1e-32
ref|XP_001907846.1| unnamed protein product [Podospora anse... 145 1e-32
emb|CAG05638.1| unnamed protein product [Tetraodon nigrovir... 144 2e-32
ref|NP_488261.1| hypothetical protein all4221 [Nostoc sp. P... 144 3e-32
emb|CAN65368.1| hypothetical protein [Vitis vinifera] 143 3e-32
pir||D71425 probable ATsEH - Arabidopsis thaliana 143 3e-32
ref|NP_001099464.1| abhydrolase domain containing 7 [Rattus... 143 5e-32
ref|XP_001389832.1| hypothetical protein An01g14420 [Asperg... 142 5e-32
ref|YP_001277175.1| alpha/beta hydrolase fold [Roseiflexus ... 142 7e-32
ref|YP_002785957.1| putative hydrolase, alpha/beta fold fam... 142 8e-32
ref|NP_001064968.1| Os10g0498500 [Oryza sativa (japonica cu... 142 8e-32
gb|EAY79083.1| hypothetical protein OsI_033042 [Oryza sativ... 142 8e-32
emb|CAO23956.1| unnamed protein product [Vitis vinifera] 142 1e-31
ref|ZP_01623368.1| epoxide hydrolase-like protein [Lyngbya ... 142 1e-31
ref|ZP_01728131.1| Alpha/beta hydrolase fold protein [Cyano... 141 1e-31
ref|XP_001367122.1| PREDICTED: hypothetical protein [Monode... 141 1e-31
ref|NP_681708.1| putative hydrolase [Thermosynechococcus el... 141 1e-31
emb|CAN65686.1| hypothetical protein [Vitis vinifera] 140 2e-31
gb|EAY79085.1| hypothetical protein OsI_033044 [Oryza sativ... 140 3e-31
ref|NP_388739.1| hypothetical protein BSU08590 [Bacillus su... 140 3e-31
ref|YP_722358.1| alpha/beta hydrolase fold [Trichodesmium e... 139 4e-31
gb|EDL40330.1| mCG14254 [Mus musculus] 139 7e-31
gb|AAI45798.1| Abhd9 protein [Mus musculus] 139 7e-31
gb|ABN08019.1| Epoxide hydrolase [Medicago truncatula] 139 8e-31
ref|XP_699161.2| PREDICTED: hypothetical protein [Danio rerio] 139 8e-31
ref|ZP_02976857.1| alpha/beta hydrolase fold [Cyanothece sp... 139 8e-31
gb|AAL16157.1|AF428389_1 At2g26740/F18A8.11 [Arabidopsis th... 139 9e-31
ref|XP_001253483.1| PREDICTED: hypothetical protein [Bos ta... 137 2e-30
ref|XP_001229448.1| hypothetical protein CHGG_02932 [Chaeto... 137 2e-30
ref|NP_001064966.1| Os10g0498200 [Oryza sativa (japonica cu... 137 2e-30
sp|Q3V1F8|ABHD9_MOUSE Abhydrolase domain-containing protein... 136 4e-30
ref|NP_001028335.1| abhydrolase domain containing 9 [Mus mu... 136 4e-30
ref|YP_001519646.1| alpha/beta hydrolase fold [Acaryochlori... 136 5e-30
ref|XP_001217680.1| predicted protein [Aspergillus terreus ... 136 6e-30
ref|XP_001805159.1| hypothetical protein SNOG_14994 [Phaeos... 135 6e-30
ref|ZP_01895551.1| alpha/beta hydrolase fold protein [Marin... 135 7e-30
ref|XP_512451.2| PREDICTED: abhydrolase domain containing 9... 135 7e-30
ref|NP_079070.1| abhydrolase domain containing 9 [Homo sapi... 135 8e-30
ref|XP_957821.1| hypothetical protein NCU00350 [Neurospora ... 135 8e-30
ref|XP_756027.1| epoxide hydrolase [Aspergillus fumigatus A... 134 2e-29
ref|NP_001102458.1| abhydrolase domain containing 9 [Rattus... 134 2e-29
ref|YP_174259.1| hypothetical protein ABC0759 [Bacillus cla... 134 3e-29
ref|NP_682856.1| epoxide hydrolase homolog [Thermosynechoco... 134 3e-29
ref|YP_001641284.1| alpha/beta hydrolase fold [Methylobacte... 133 4e-29
ref|ZP_01017814.1| Alpha/beta hydrolase fold protein [Parvu... 132 6e-29
ref|XP_368050.2| hypothetical protein MGG_07954 [Magnaporth... 130 3e-28
ref|YP_001926939.1| alpha/beta hydrolase fold [Methylobacte... 130 3e-28
ref|YP_001770315.1| alpha/beta hydrolase fold [Methylobacte... 130 4e-28
ref|ZP_02185384.1| hypothetical protein CAT7_04257 [Carnoba... 129 6e-28
ref|YP_001753313.1| alpha/beta hydrolase fold [Methylobacte... 129 7e-28
ref|NP_296269.1| epoxide hydrolase-related protein [Deinoco... 129 8e-28
ref|XP_875305.1| PREDICTED: hypothetical protein [Bos taurus] 128 1e-27
ref|YP_001485500.1| possible alpha/beta family hydrolase [B... 127 2e-27
ref|XP_504164.1| hypothetical protein [Yarrowia lipolytica]... 127 2e-27
ref|YP_001614132.1| Epoxide hydrolase [Sorangium cellulosum... 127 2e-27
ref|NP_497268.1| K02F3.6 [Caenorhabditis elegans] >gi|15375... 127 3e-27
ref|XP_796464.1| PREDICTED: hypothetical protein [Strongylo... 127 4e-27
ref|ZP_02055448.1| alpha/beta hydrolase fold [Methylobacter... 127 4e-27
gb|EAZ16569.1| hypothetical protein OsJ_030778 [Oryza sativ... 126 4e-27
ref|YP_458350.1| possible epoxide hydrolase-related protein... 126 4e-27
gb|AAL58264.1|AC068923_6 putative epoxide hydrolase [Oryza ... 126 5e-27
>ref|NP_001970.2| epoxide hydrolase 2, cytoplasmic [Homo sapiens]
sp|P34913|HYES_HUMAN Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
pdb|1S8O|A Chain A, Human Soluble Epoxide Hydrolase
pdb|1VJ5|A Chain A, Human Soluble Epoxide Hydrolase- N-Cyclohexyl-N'-(4-
Iodophenyl)urea Complex
pdb|1ZD2|P Chain P, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Ethanoic Acid Complex
pdb|1ZD3|A Chain A, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Butyric Acid Complex
pdb|1ZD4|A Chain A, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Hexanoic Acid Complex
pdb|1ZD5|A Chain A, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Heptanoic Acid Complex
gb|AAG14966.1|AF233334_1 soluble epoxide hydrolase [Homo sapiens]
emb|CAA65751.1| epoxide hydrolase [Homo sapiens]
gb|AAH07708.1| Epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAH11628.1| Epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAH13874.1| Epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAP35531.1| epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAX42304.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
gb|AAX42305.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
gb|EAW63548.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_b [Homo sapiens]
gb|ABM83675.1| epoxide hydrolase 2, cytoplasmic [synthetic construct]
gb|ABM86963.1| epoxide hydrolase 2, cytoplasmic [synthetic construct]
gb|ACD11487.1| epoxide hydrolase 2, cytoplasmic [Homo sapiens]
Length = 555
Score = 1160 bits (3001), Expect = 0.0, Method: Composition-based stats.
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>gb|AAP36260.1| Homo sapiens epoxide hydrolase 2, cytoplasmic [synthetic construct]
gb|AAX29746.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
gb|AAX29747.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
Length = 556
Score = 1160 bits (3001), Expect = 0.0, Method: Composition-based stats.
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>gb|AAG14967.1|AF233335_1 soluble epoxide hydrolase [Homo sapiens]
Length = 555
Score = 1158 bits (2996), Expect = 0.0, Method: Composition-based stats.
Identities = 554/555 (99%), Positives = 555/555 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGY+VLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYQVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>gb|AAG14968.1|AF233336_1 soluble epoxide hydrolase [Homo sapiens]
Length = 556
Score = 1155 bits (2989), Expect = 0.0, Method: Composition-based stats.
Identities = 555/556 (99%), Positives = 555/556 (99%), Gaps = 1/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLS-RTFKSLFRASDESVLSM 419
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLS RTFKSLFRASDESVLSM
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRRTFKSLFRASDESVLSM 420
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS
Sbjct: 421 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 480
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI
Sbjct: 481 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 540
Query: 540 KWLDSDARNPPVVSKM 555
KWLDSDARNPPVVSKM
Sbjct: 541 KWLDSDARNPPVVSKM 556
>ref|XP_001163779.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 3 [Pan
troglodytes]
ref|XP_001163923.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 7 [Pan
troglodytes]
ref|XP_519676.2| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 8 [Pan
troglodytes]
Length = 555
Score = 1152 bits (2979), Expect = 0.0, Method: Composition-based stats.
Identities = 549/555 (98%), Positives = 554/555 (99%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG+SS
Sbjct: 241 YVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGKSS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>gb|AAA02756.1| cytosolic epoxide hydrolase
Length = 554
Score = 1149 bits (2972), Expect = 0.0, Method: Composition-based stats.
Identities = 552/555 (99%), Positives = 552/555 (99%), Gaps = 1/555 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLR AVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRGAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELG PAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELG-WPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 299
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 300 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 359
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 360 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 419
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 420 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 479
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 480 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 539
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 540 WLDSDARNPPVVSKM 554
>gb|EAW63547.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Homo sapiens]
Length = 568
Score = 1148 bits (2970), Expect = 0.0, Method: Composition-based stats.
Identities = 554/568 (97%), Positives = 554/568 (97%), Gaps = 13/568 (2%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPR-------------GLLNDAFQKGGPE 47
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALP GLLNDAFQKGGPE
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPSSGGWKSKIKMSAGGLLNDAFQKGGPE 60
Query: 48 GATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQ 107
GATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQ
Sbjct: 61 GATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQ 120
Query: 108 AALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYK 167
AALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYK
Sbjct: 121 AALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYK 180
Query: 168 FLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAP 227
FLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAP
Sbjct: 181 FLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAP 240
Query: 228 LPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYR 287
LPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYR
Sbjct: 241 LPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYR 300
Query: 288 VLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALF 347
VLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALF
Sbjct: 301 VLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALF 360
Query: 348 YPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS 407
YPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS
Sbjct: 361 YPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS 420
Query: 408 LFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYR 467
LFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYR
Sbjct: 421 LFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYR 480
Query: 468 NMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ 527
NMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ
Sbjct: 481 NMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ 540
Query: 528 MDKPTEVNQILIKWLDSDARNPPVVSKM 555
MDKPTEVNQILIKWLDSDARNPPVVSKM
Sbjct: 541 MDKPTEVNQILIKWLDSDARNPPVVSKM 568
>ref|XP_001163896.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 6 [Pan
troglodytes]
Length = 560
Score = 1136 bits (2938), Expect = 0.0, Method: Composition-based stats.
Identities = 544/560 (97%), Positives = 551/560 (98%), Gaps = 5/560 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQ-----AGYRVLAMDMKG 295
YVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQ+ L + AGYRVLAMDMKG
Sbjct: 241 YVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQVRKLGKMQPVRAGYRVLAMDMKG 300
Query: 296 YGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV 355
YG+SSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV
Sbjct: 301 YGKSSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV 360
Query: 356 ASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES 415
ASLNTPFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES
Sbjct: 361 ASLNTPFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES 420
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW
Sbjct: 421 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 480
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 535
ACKSLGRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVN
Sbjct: 481 ACKSLGRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 540
Query: 536 QILIKWLDSDARNPPVVSKM 555
QILIKWLDSDARNPPVVSKM
Sbjct: 541 QILIKWLDSDARNPPVVSKM 560
>ref|XP_001109474.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic [Macaca
mulatta]
Length = 556
Score = 1094 bits (2830), Expect = 0.0, Method: Composition-based stats.
Identities = 520/556 (93%), Positives = 539/556 (96%), Gaps = 1/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAF KGGPEGATTRLM+GEITL
Sbjct: 1 MALRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFHKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCS+T++V LPKNFS+ EIF KAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSQTSEVSLPKNFSVNEIFGKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELK HFDFLIESCQVGMVKPEPQIY+FLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKTHFDFLIESCQVGMVKPEPQIYRFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD+G+NLKPARDLGMVTILVQDTDTAL+ELEKVTGIQLLNTPAPLPT CNPSD+SHG
Sbjct: 181 VFLDDVGSNLKPARDLGMVTILVQDTDTALRELEKVTGIQLLNTPAPLPTCCNPSDVSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVT+KP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRV+AMDMKGYGESS
Sbjct: 241 YVTIKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVIAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFL-DKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
APPEIEEYCMEVLCKE V L +LGLSQAVFIGHDWGG+LVWYMALFYPERVRAVASLN
Sbjct: 301 APPEIEEYCMEVLCKETVPRLAGELGLSQAVFIGHDWGGVLVWYMALFYPERVRAVASLN 360
Query: 360 TPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSM 419
TPFIPANPN+ PLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSM
Sbjct: 361 TPFIPANPNVPPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSM 420
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HKVCE GGLFV +PEEPSLSRMV+EEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS
Sbjct: 421 HKVCEMGGLFVRTPEEPSLSRMVSEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 480
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKP EVNQILI
Sbjct: 481 LGRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPAEVNQILI 540
Query: 540 KWLDSDARNPPVVSKM 555
KWL+SDARNPPVVSKM
Sbjct: 541 KWLESDARNPPVVSKM 556
>ref|XP_001163861.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 5 [Pan
troglodytes]
Length = 523
Score = 1063 bits (2748), Expect = 0.0, Method: Composition-based stats.
Identities = 518/555 (93%), Positives = 523/555 (94%), Gaps = 32/555 (5%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVK IPALAQAGYRVLAMDMKGYG+SS
Sbjct: 241 YVTVK--------------------------------IPALAQAGYRVLAMDMKGYGKSS 268
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 269 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 328
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 329 PFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 388
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 389 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 448
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 449 GRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 508
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 509 WLDSDARNPPVVSKM 523
>gb|EAW63549.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_c [Homo sapiens]
Length = 502
Score = 1055 bits (2727), Expect = 0.0, Method: Composition-based stats.
Identities = 502/502 (100%), Positives = 502/502 (100%)
Query: 54 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 113
MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR
Sbjct: 1 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 60
Query: 114 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 173
KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL
Sbjct: 61 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 120
Query: 174 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 233
KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN
Sbjct: 121 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 180
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM
Sbjct: 181 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 240
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR
Sbjct: 241 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 300
Query: 354 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 413
AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD
Sbjct: 301 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 360
Query: 414 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 473
ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW
Sbjct: 361 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 420
Query: 474 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 533
KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE
Sbjct: 421 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 480
Query: 534 VNQILIKWLDSDARNPPVVSKM 555
VNQILIKWLDSDARNPPVVSKM
Sbjct: 481 VNQILIKWLDSDARNPPVVSKM 502
>ref|XP_001163819.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 4 [Pan
troglodytes]
Length = 514
Score = 1050 bits (2716), Expect = 0.0, Method: Composition-based stats.
Identities = 508/555 (91%), Positives = 513/555 (92%), Gaps = 41/555 (7%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE- 179
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
LLNTPAPLPTSCNPSDMSHG
Sbjct: 180 ----------------------------------------LLNTPAPLPTSCNPSDMSHG 199
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG+SS
Sbjct: 200 YVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGKSS 259
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 260 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 319
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 320 PFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 379
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 380 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 439
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 440 GRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 499
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 500 WLDSDARNPPVVSKM 514
>ref|XP_001163527.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 1 [Pan
troglodytes]
Length = 502
Score = 1046 bits (2705), Expect = 0.0, Method: Composition-based stats.
Identities = 496/502 (98%), Positives = 501/502 (99%)
Query: 54 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 113
M+GEITLSQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLR
Sbjct: 1 MRGEITLSQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLR 60
Query: 114 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 173
KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL
Sbjct: 61 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 120
Query: 174 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 233
KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN
Sbjct: 121 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 180
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
PSDMSHGYVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM
Sbjct: 181 PSDMSHGYVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 240
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
KGYG+SSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR
Sbjct: 241 KGYGKSSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 300
Query: 354 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 413
AVASLNTPFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD
Sbjct: 301 AVASLNTPFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 360
Query: 414 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 473
ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW
Sbjct: 361 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 420
Query: 474 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 533
KWACKSLGRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTE
Sbjct: 421 KWACKSLGRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTE 480
Query: 534 VNQILIKWLDSDARNPPVVSKM 555
VNQILIKWLDSDARNPPVVSKM
Sbjct: 481 VNQILIKWLDSDARNPPVVSKM 502
>gb|EAW63551.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_e [Homo sapiens]
Length = 489
Score = 1029 bits (2660), Expect = 0.0, Method: Composition-based stats.
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 67 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 126
MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW
Sbjct: 1 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 60
Query: 127 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 186
LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI
Sbjct: 61 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 120
Query: 187 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 246
GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP
Sbjct: 121 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 180
Query: 247 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 306
RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE
Sbjct: 181 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 240
Query: 307 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 366
EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN
Sbjct: 241 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 300
Query: 367 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 426
PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG
Sbjct: 301 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 360
Query: 427 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 486
GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI
Sbjct: 361 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 420
Query: 487 PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 546
PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA
Sbjct: 421 PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 480
Query: 547 RNPPVVSKM 555
RNPPVVSKM
Sbjct: 481 RNPPVVSKM 489
>ref|XP_001163565.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 2 [Pan
troglodytes]
Length = 489
Score = 1020 bits (2638), Expect = 0.0, Method: Composition-based stats.
Identities = 484/489 (98%), Positives = 488/489 (99%)
Query: 67 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 126
MEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW
Sbjct: 1 MEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 60
Query: 127 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 186
LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI
Sbjct: 61 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 120
Query: 187 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 246
GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP
Sbjct: 121 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 180
Query: 247 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 306
VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG+SSAPPEIE
Sbjct: 181 GVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGKSSAPPEIE 240
Query: 307 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 366
EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN
Sbjct: 241 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 300
Query: 367 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 426
PN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG
Sbjct: 301 PNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 360
Query: 427 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 486
GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI
Sbjct: 361 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 420
Query: 487 PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 546
PALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA
Sbjct: 421 PALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 480
Query: 547 RNPPVVSKM 555
RNPPVVSKM
Sbjct: 481 RNPPVVSKM 489
>ref|XP_001492725.1| PREDICTED: similar to soluble epoxide hydrolase [Equus caballus]
Length = 555
Score = 940 bits (2430), Expect = 0.0, Method: Composition-based stats.
Identities = 437/555 (78%), Positives = 495/555 (89%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP++ GR EE LALPRG L++A GP+ + RL+ GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSIARAFGRAEEDLALPRGFLSEALNLKGPDESIARLVTGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+P ++E+C+K S+ + + LP+ FSI +IF KAISARKIN PMLQAAL LRKKGFTT
Sbjct: 61 SQWVPFIDEDCKKRSKNSGINLPEEFSINQIFAKAISARKINHPMLQAALTLRKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD +ER LAQL+CEL+ HFDFLIESC++ M KPEPQIYK++LDTLKASP+EV
Sbjct: 121 ILTNNWLDDSSERGTLAQLLCELRPHFDFLIESCRIRMAKPEPQIYKYVLDTLKASPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGA LKPARDLGMVTILV+DTDTAL+ELEKVTG+QLL T APLPT C+P+D+SHG
Sbjct: 181 VFLDDIGAYLKPARDLGMVTILVRDTDTALRELEKVTGMQLLKTAAPLPTPCSPNDVSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLHFVELG GPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHFVELGCGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLAVDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY MEVLCK+MVTFLDKLG+SQAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYSMEVLCKDMVTFLDKLGISQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+PANPN+SP+E IKANPVF+YQLYFQEPGVAEAELEQNLSRTFKS FR SDE LS
Sbjct: 361 PFMPANPNVSPMEIIKANPVFNYQLYFQEPGVAEAELEQNLSRTFKSFFRTSDEGFLSTS 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+VCE GGLFV +PEEPSLS MV+EE+IQFYVQQF+KSGFRGPLNWYRN+ERNW+W CK
Sbjct: 421 RVCERGGLFVAAPEEPSLSSMVSEEDIQFYVQQFRKSGFRGPLNWYRNVERNWQWGCKGS 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKD VLVP+MS+HMEDWIPHLKRGHI+DCGHWTQM+KPTE+NQIL +
Sbjct: 481 GRKILIPALMVTAEKDVVLVPEMSKHMEDWIPHLKRGHIKDCGHWTQMEKPTELNQILTE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DAR+P VVSK+
Sbjct: 541 WLETDARDPLVVSKL 555
>ref|XP_534566.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 1
[Canis familiaris]
Length = 556
Score = 940 bits (2429), Expect = 0.0, Method: Composition-based stats.
Identities = 436/556 (78%), Positives = 497/556 (89%), Gaps = 1/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+QLL T A LP CNPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQLLQTAAALPVPCNPSDMSHV 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 301 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD-ESVLSM 419
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD + L++
Sbjct: 361 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKPFLNV 420
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+V E GGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W CK
Sbjct: 421 GRVRERGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGCKG 480
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
+GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQILI
Sbjct: 481 VGRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQILI 540
Query: 540 KWLDSDARNPPVVSKM 555
+WL++DAR+PPVVSK+
Sbjct: 541 EWLETDARDPPVVSKL 556
>ref|XP_857471.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 3
[Canis familiaris]
Length = 555
Score = 939 bits (2426), Expect = 0.0, Method: Composition-based stats.
Identities = 435/555 (78%), Positives = 493/555 (88%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+QLL T A LP CNPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQLLQTAAALPVPCNPSDMSHV 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 301 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD V
Sbjct: 361 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKVSVAE 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+ AGGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W CK +
Sbjct: 421 RWLFAGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGCKGV 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQILI+
Sbjct: 481 GRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQILIE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DAR+PPVVSK+
Sbjct: 541 WLETDARDPPVVSKL 555
>ref|NP_001001641.1| soluble epoxide hydrolase [Sus scrofa]
sp|Q6Q2C2|HYES_PIG Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
gb|AAS68016.1| soluble epoxide hydrolase [Sus scrofa]
Length = 555
Score = 938 bits (2424), Expect = 0.0, Method: Composition-based stats.
Identities = 430/555 (77%), Positives = 494/555 (89%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP++ R EE LALPRG LN+AF+KGG +G+ R+M GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSITTSWARAEEKLALPRGFLNEAFKKGGQDGSVARVMTGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+P MEE+CRKC+E + + LP+NFS+K IFDKA+S +KIN PMLQAAL L+KKGF+T
Sbjct: 61 SQWVPFMEEDCRKCAEDSGIRLPENFSVKHIFDKALSEKKINYPMLQAALTLKKKGFSTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD A+R AQLMCEL+ HFDFLIESC+VGM KP+PQIYK +LDTLKA P+EV
Sbjct: 121 ILTNNWLDDSAQRGSRAQLMCELRPHFDFLIESCRVGMAKPDPQIYKLMLDTLKAEPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD+G +LKP RDLGM TILV+DTDTAL+ELEKVTG+QLL TPA PTSC+PS +SHG
Sbjct: 181 VFLDDVGTHLKPVRDLGMATILVRDTDTALRELEKVTGVQLLQTPALPPTSCDPSALSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLHFVE+GSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVLIKPGVRLHFVEMGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLAVDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY +EVLCK+MVTFL+KLGLSQAVFIGHDWGG+LVW MALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYSLEVLCKDMVTFLNKLGLSQAVFIGHDWGGVLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+P+NPN+SP+E IKANPVFDYQLYFQEPGVAEAELEQNL RTFK+ FRA DE+ L+ +
Sbjct: 361 PFMPSNPNVSPMEIIKANPVFDYQLYFQEPGVAEAELEQNLDRTFKNFFRAHDETFLTTN 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+V E GGLFV +PEEPSLSR+VTEE+IQFYVQQFKKSGFRGPLNWYRNMERNW+W CK
Sbjct: 421 RVRELGGLFVGTPEEPSLSRLVTEEDIQFYVQQFKKSGFRGPLNWYRNMERNWQWGCKGS 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAE D VL P+MS+HME+WIPHLKRGHI+DCGHWTQ+DKP E+N+ILI+
Sbjct: 481 GRKILIPALMVTAENDLVLHPKMSKHMENWIPHLKRGHIKDCGHWTQIDKPAELNRILIE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DARNP V SK+
Sbjct: 541 WLETDARNPLVDSKL 555
>ref|XP_857554.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 4
[Canis familiaris]
Length = 554
Score = 928 bits (2398), Expect = 0.0, Method: Composition-based stats.
Identities = 432/556 (77%), Positives = 495/556 (89%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+Q + + LP CNPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQ--SPKSALPVPCNPSDMSHV 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 239 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD-ESVLSM 419
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD + L++
Sbjct: 359 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKPFLNV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+V E GGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W CK
Sbjct: 419 GRVRERGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
+GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQILI
Sbjct: 479 VGRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
+WL++DAR+PPVVSK+
Sbjct: 539 EWLETDARDPPVVSKL 554
>ref|XP_857430.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 2
[Canis familiaris]
Length = 556
Score = 920 bits (2379), Expect = 0.0, Method: Composition-based stats.
Identities = 429/558 (76%), Positives = 489/558 (87%), Gaps = 5/558 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+Q + + LP CNPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQ--SPKSALPVPCNPSDMSHV 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 239 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE---SVL 417
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD
Sbjct: 359 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKGFETC 418
Query: 418 SMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWAC 477
+ GGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W C
Sbjct: 419 ANRPATAVGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGC 478
Query: 478 KSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQI 537
K +GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQI
Sbjct: 479 KGVGRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQI 538
Query: 538 LIKWLDSDARNPPVVSKM 555
LI+WL++DAR+PPVVSK+
Sbjct: 539 LIEWLETDARDPPVVSKL 556
>ref|NP_001069002.1| epoxide hydrolase 2, cytoplasmic [Bos taurus]
gb|AAI18307.1| Epoxide hydrolase 2, cytoplasmic [Bos taurus]
Length = 555
Score = 911 bits (2355), Expect = 0.0, Method: Composition-based stats.
Identities = 415/555 (74%), Positives = 488/555 (87%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVF+L G+L LP+ R EE LALP G L+ AF +GGP+G + R+MKGEIT
Sbjct: 1 MALRAAVFELGGILTLPSATSFWDRAEEELALPGGFLSKAFLRGGPDGPSIRVMKGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+P MEE+CRKCS+ +CLP+NFSIK+IF+K +S+RKIN PMLQAA+ L++KGFTT
Sbjct: 61 SQWVPFMEEDCRKCSKDCGICLPENFSIKQIFEKILSSRKINYPMLQAAVTLKQKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDD AER LAQ++CELK HFDFLIESCQ+GMVKP+PQIYKF+LDTLK SPSEV
Sbjct: 121 ILTNTWLDDSAERGSLAQVLCELKPHFDFLIESCQIGMVKPDPQIYKFVLDTLKISPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLD+ NLKPA ++GMVTI V DTD ALKELEKVTG+QLL T AP P SC+PS M+HG
Sbjct: 181 VFLDNFETNLKPAHEMGMVTIFVHDTDAALKELEKVTGVQLLQTSAPQPISCDPSTMTHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLHFVELGSGP VCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHFVELGSGPVVCLCHGFPESWFSWRYQIPALAQAGFRVLAVDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY +EVL K+M+TFLDKLG+SQAVFIGHDWGGMLVW +ALF+PERVRAVASLNT
Sbjct: 301 APPEIEEYSLEVLSKDMITFLDKLGISQAVFIGHDWGGMLVWTIALFHPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+P+NP +S +E IKA P F+YQLYFQEPGVAEAELE+NLSRTFKS FR++DE+ +++
Sbjct: 361 PFMPSNPKVSTMEIIKATPTFNYQLYFQEPGVAEAELEKNLSRTFKSFFRSNDETFITVS 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+ CE GGL VN+PEEP+LS+MVTEE+IQFYVQ+FKKSGFRGPLNWYRNM++NW+W K
Sbjct: 421 RTCEMGGLLVNTPEEPTLSKMVTEEDIQFYVQEFKKSGFRGPLNWYRNMDKNWEWGFKGS 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKD VL P+MS+HMEDWIPHLKRGHI+DCGHWTQM+KPTE+N+ILI+
Sbjct: 481 GRKILIPALMVTAEKDLVLTPEMSKHMEDWIPHLKRGHIKDCGHWTQMEKPTELNRILIE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DAR+ PVVSK+
Sbjct: 541 WLETDARDLPVVSKL 555
>emb|CAA85471.1| Epoxide Hydrolase [Mus musculus]
Length = 554
Score = 883 bits (2282), Expect = 0.0, Method: Composition-based stats.
Identities = 407/556 (73%), Positives = 483/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ G R+EEALALPR L A+Q PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+ RK S+T LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT
Sbjct: 61 SQWVPLMDESYRKSSKTCGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P+EV
Sbjct: 121 IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q APLP CNP+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQF--PEAPLPVPCNPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES-VLSM 419
PF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE+ +++
Sbjct: 359 PFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK
Sbjct: 419 HKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLQTEVQNPSVTSKI 554
>ref|NP_031966.2| epoxide hydrolase 2, cytoplasmic [Mus musculus]
sp|P34914|HYES_MOUSE Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
pdb|1CQZ|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase.
pdb|1CQZ|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase.
pdb|1CR6|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cpu Inhibitor
pdb|1CR6|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cpu Inhibitor
pdb|1EK1|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Ciu Inhibitor
pdb|1EK1|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Ciu Inhibitor
pdb|1EK2|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cdu Inhibitor
pdb|1EK2|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cdu Inhibitor
gb|AAA37555.1| epoxide hydrolase
gb|AAH15087.1| Epoxide hydrolase 2, cytoplasmic [Mus musculus]
gb|EDL36005.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Mus musculus]
Length = 554
Score = 881 bits (2277), Expect = 0.0, Method: Composition-based stats.
Identities = 406/556 (73%), Positives = 482/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ G R+EEALALPR L A+Q PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT
Sbjct: 61 SQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P+EV
Sbjct: 121 IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q APLP CNP+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQF--PEAPLPVPCNPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES-VLSM 419
PF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE+ +++
Sbjct: 359 PFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK
Sbjct: 419 HKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLQTEVQNPSVTSKI 554
>dbj|BAE25172.1| unnamed protein product [Mus musculus]
Length = 554
Score = 880 bits (2273), Expect = 0.0, Method: Composition-based stats.
Identities = 405/556 (72%), Positives = 482/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ G R+EEALALPR L A+Q PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT
Sbjct: 61 SQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEP+IY FLLDTLKA P+EV
Sbjct: 121 IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPRIYNFLLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q APLP CNP+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQF--PEAPLPVPCNPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES-VLSM 419
PF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE+ +++
Sbjct: 359 PFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK
Sbjct: 419 HKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLQTEVQNPSVTSKI 554
>ref|NP_075225.1| epoxide hydrolase 2, cytoplasmic [Rattus norvegicus]
sp|P80299|HYES_RAT Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
emb|CAA46211.1| epoxide hydrolase [Rattus norvegicus]
Length = 554
Score = 874 bits (2259), Expect = 0.0, Method: Composition-based stats.
Identities = 405/556 (72%), Positives = 481/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ GVL TEEALALPR L AFQ PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+CRK S+ LP+NFSI EIF +A++AR INRPMLQAA L+KKGFTT
Sbjct: 61 SQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIYKF+LDTLKA P+EV
Sbjct: 121 IVTNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV+DT +AL+ELEKVTG Q APLP C+P+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQF--PEAPLPVPCSPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LC+EMVTFL+KLG+ QAVFIGHDW G+LVW MALF+PERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMALFHPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
P +P NP +SP+E I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FR SD+ +L++
Sbjct: 359 PLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+K E GG+ V +PE+P +S++ TEEEI++Y+QQFKKSGFRGPLNWYRN ERNWKW+CK+
Sbjct: 419 NKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLNWYRNTERNWKWSCKA 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME+WIP LKRGHIEDCGHWTQ++KP EVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGHWTQIEKPAEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLKTEIQNPSVTSKI 554
>gb|AAH85732.1| Epoxide hydrolase 2, cytoplasmic [Rattus norvegicus]
gb|EDL85376.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Rattus norvegicus]
Length = 554
Score = 870 bits (2248), Expect = 0.0, Method: Composition-based stats.
Identities = 404/556 (72%), Positives = 479/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ GVL TEEALALPR L AFQ PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+CRK S+ LP+NFSI EIF +A++AR INRPMLQAA L+KKGFTT
Sbjct: 61 SQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIYKF+LDTLKA P+EV
Sbjct: 121 IITNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV+DT +AL+ELEKVTG Q APLP C+P+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQF--PEAPLPVPCSPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP + LHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGICLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LC+EMVTFL+KLG+ QAVFIGHDW G+LVW MALF+PERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMALFHPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
P +P NP +SP+E I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FR SD+ +L++
Sbjct: 359 PLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+K E GG+ V +PE+P +S++ TEEEI++Y+QQFKKSGFRGPLNWYRN ERNWKW CK+
Sbjct: 419 NKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLNWYRNTERNWKWNCKA 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME+WIP LKRGHIEDCGHWTQ++KP EVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGHWTQIEKPAEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLKTEIQNPSVTSKI 554
>gb|EDL36006.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_b [Mus musculus]
Length = 501
Score = 822 bits (2124), Expect = 0.0, Method: Composition-based stats.
Identities = 374/503 (74%), Positives = 445/503 (88%), Gaps = 3/503 (0%)
Query: 54 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 113
MKG+IT SQW+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+
Sbjct: 1 MKGKITFSQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALK 60
Query: 114 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 173
KKGFTT I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTL
Sbjct: 61 KKGFTTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTL 120
Query: 174 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 233
KA P+EVVFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q APLP CN
Sbjct: 121 KAKPNEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQF--PEAPLPVPCN 178
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
P+D+SHGYVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DM
Sbjct: 179 PNDVSHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDM 238
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
KGYG+SS+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVR
Sbjct: 239 KGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVR 298
Query: 354 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 413
AVASLNTPF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASD
Sbjct: 299 AVASLNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASD 358
Query: 414 ES-VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERN 472
E+ +++HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERN
Sbjct: 359 ETGFIAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERN 418
Query: 473 WKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPT 532
WKW+CK LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPT
Sbjct: 419 WKWSCKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPT 478
Query: 533 EVNQILIKWLDSDARNPPVVSKM 555
EVNQILIKWL ++ +NP V SK+
Sbjct: 479 EVNQILIKWLQTEVQNPSVTSKI 501
>gb|EDL85377.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_b [Rattus norvegicus]
Length = 512
Score = 816 bits (2109), Expect = 0.0, Method: Composition-based stats.
Identities = 374/511 (73%), Positives = 447/511 (87%), Gaps = 3/511 (0%)
Query: 46 PEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPM 105
PEG T +LMKG+IT SQW+PLM+E+CRK S+ LP+NFSI EIF +A++AR INRPM
Sbjct: 4 PEGPTEQLMKGKITFSQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPM 63
Query: 106 LQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQI 165
LQAA L+KKGFTT I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQI
Sbjct: 64 LQAAAALKKKGFTTCIITNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQI 123
Query: 166 YKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTP 225
YKF+LDTLKA P+EVVFLDD G+NLKPARD+GMVTILV+DT +AL+ELEKVTG Q
Sbjct: 124 YKFVLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQF--PE 181
Query: 226 APLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAG 285
APLP C+P+D+SHGYVTVKP + LHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG
Sbjct: 182 APLPVPCSPNDVSHGYVTVKPGICLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQAG 241
Query: 286 YRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMA 345
+RVLA+DMKGYG+SS+PPEIEEY ME+LC+EMVTFL+KLG+ QAVFIGHDW G+LVW MA
Sbjct: 242 FRVLAIDMKGYGDSSSPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMA 301
Query: 346 LFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTF 405
LF+PERVRAVASLNTP +P NP +SP+E I++ PVF+YQLYFQEPGVAEAELE+N+SRTF
Sbjct: 302 LFHPERVRAVASLNTPLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTF 361
Query: 406 KSLFRASDE-SVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLN 464
KS FR SD+ +L+++K E GG+ V +PE+P +S++ TEEEI++Y+QQFKKSGFRGPLN
Sbjct: 362 KSFFRTSDDMGLLTVNKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLN 421
Query: 465 WYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGH 524
WYRN ERNWKW CK+LGRKIL+PALMVTAEKD VL P+MS++ME+WIP LKRGHIEDCGH
Sbjct: 422 WYRNTERNWKWNCKALGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGH 481
Query: 525 WTQMDKPTEVNQILIKWLDSDARNPPVVSKM 555
WTQ++KP EVNQILIKWL ++ +NP V SK+
Sbjct: 482 WTQIEKPAEVNQILIKWLKTEIQNPSVTSKI 512
>gb|AAM28238.1| ovary-selective epoxide hydrolase [Mus musculus]
Length = 536
Score = 813 bits (2099), Expect = 0.0, Method: Composition-based stats.
Identities = 369/499 (73%), Positives = 440/499 (88%), Gaps = 3/499 (0%)
Query: 58 ITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGF 117
I S+W+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGF
Sbjct: 40 IHTSEWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGF 99
Query: 118 TTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASP 177
TT I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P
Sbjct: 100 TTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKP 159
Query: 178 SEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDM 237
+EVVFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q APLP CNP+D+
Sbjct: 160 NEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQF--PEAPLPVPCNPNDV 217
Query: 238 SHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG 297
SHGYVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG
Sbjct: 218 SHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYG 277
Query: 298 ESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVAS 357
+SS+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVAS
Sbjct: 278 DSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVAS 337
Query: 358 LNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES-V 416
LNTPF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE+
Sbjct: 338 LNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGF 397
Query: 417 LSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWA 476
+++HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+
Sbjct: 398 IAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWS 457
Query: 477 CKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQ 536
CK LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQ
Sbjct: 458 CKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQ 517
Query: 537 ILIKWLDSDARNPPVVSKM 555
ILIKWL ++ +NP V SK+
Sbjct: 518 ILIKWLQTEVQNPSVTSKI 536
>gb|ABU95055.1| epoxide hydrolase 2C [Mus musculus]
Length = 488
Score = 800 bits (2066), Expect = 0.0, Method: Composition-based stats.
Identities = 364/490 (74%), Positives = 433/490 (88%), Gaps = 3/490 (0%)
Query: 67 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 126
M+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT I+TN W
Sbjct: 1 MDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNW 60
Query: 127 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 186
LDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P+EVVFLDD
Sbjct: 61 LDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDF 120
Query: 187 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 246
G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q APLP CNP+D+SHGYVTVKP
Sbjct: 121 GSNLKPARDMGMVTILVHNTASALRELEKVTGTQF--PEAPLPVPCNPNDVSHGYVTVKP 178
Query: 247 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 306
+RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS+PPEIE
Sbjct: 179 GIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIE 238
Query: 307 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 366
EY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNTPF+P +
Sbjct: 239 EYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPD 298
Query: 367 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES-VLSMHKVCEA 425
P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE+ +++HK E
Sbjct: 299 PDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEI 358
Query: 426 GGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKIL 485
GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK LGRKIL
Sbjct: 359 GGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKIL 418
Query: 486 IPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSD 545
+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILIKWL ++
Sbjct: 419 VPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTE 478
Query: 546 ARNPPVVSKM 555
+NP V SK+
Sbjct: 479 VQNPSVTSKI 488
>ref|XP_001380051.1| PREDICTED: similar to soluble epoxide hydrolase [Monodelphis
domestica]
Length = 562
Score = 729 bits (1881), Expect = 0.0, Method: Composition-based stats.
Identities = 347/560 (61%), Positives = 432/560 (77%), Gaps = 7/560 (1%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAA+FDL GVL P++ + + EEALALPRG LN +GG E L+KGEIT
Sbjct: 1 MGLRAALFDLGGVLVHPSMNIIFSQAEEALALPRGFLNKVITQGGLESPYVHLIKGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE+CRK S + CLP+ FS+++IF+ IS KIN PML+AA+ LR KG+ T
Sbjct: 61 SQWVPLMEEDCRKLSVASNFCLPEQFSLQKIFEDMISEGKINYPMLRAAITLRNKGYKTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD +R+ +AQLMC L HFD +IESC++GMVKP+P+IYKF L+ LK +P E
Sbjct: 121 ILTNNWLDDGLQRNVIAQLMCTLSKHFDLVIESCRIGMVKPDPEIYKFALEALKVAPHEA 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD GANLK AR+LGMVTIL QDTD ALKELEK TG+Q N P + +PS+++HG
Sbjct: 181 VFLDDTGANLKKARELGMVTILAQDTDMALKELEKSTGVQFPNHDMERPIAVHPSNIAHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV VKP V+LHFVE GSGP VCL HGFPE WYSW+ QIP L +AG+RV+A+D+KG+G+SS
Sbjct: 241 YVEVKPGVQLHFVEKGSGPVVCLFHGFPEFWYSWKCQIPVLVEAGFRVIALDLKGFGDSS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
AP EIEEY EV+CKE++TFLDKL +SQA+ IGHDWGG+LVW MA+FYPERVRAVAS+N+
Sbjct: 301 APYEIEEYSQEVICKELITFLDKLDISQAICIGHDWGGLLVWNMAIFYPERVRAVASVNS 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
PF P +P + E +K NPVF+YQ YFQ+PGVAEAELEQ+L+RTFK LFRASDE V +
Sbjct: 361 PFFPPDPVVPLKEKLKKNPVFNYQFYFQKPGVAEAELEQDLTRTFKILFRASDERKVCML 420
Query: 420 HKVCEAG--GLF----VNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 473
H G GLF + E P LS M+TEE+I +YVQQ+KKSGFRGPLNWYRN + NW
Sbjct: 421 HTGTIVGNRGLFFIGILKKIENPFLSWMLTEEDINYYVQQYKKSGFRGPLNWYRNHDANW 480
Query: 474 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 533
+W+C + RKIL+PALMV AE D VL P++S++ME WIPHLKR +I++CGHWTQ+++P E
Sbjct: 481 RWSCMATKRKILVPALMVIAENDVVLSPKLSENMEKWIPHLKRAYIKNCGHWTQLERPRE 540
Query: 534 VNQILIKWLDSDARNPPVVS 553
+NQILI+WL + P +VS
Sbjct: 541 LNQILIEWLKDVTKTPSMVS 560
>ref|NP_001006912.1| epoxide hydrolase 2, cytoplasmic [Xenopus tropicalis]
gb|AAH75370.1| Epoxide hydrolase 2, cytoplasmic [Xenopus tropicalis]
Length = 560
Score = 684 bits (1765), Expect = 0.0, Method: Composition-based stats.
Identities = 317/557 (56%), Positives = 410/557 (73%), Gaps = 6/557 (1%)
Query: 4 RAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQW 63
R +FDL GVL P R E +L+LP G L + F + G EG R +G+I S++
Sbjct: 5 RFVLFDLGGVLLTPGPQVAFQRLERSLSLPSGFLQNVFVRSGSEGPFARAERGQIPFSKF 64
Query: 64 IPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILT 123
I M++ C+ +E + V LP +FS+++ F + IN+PML+AA+ LR GF T +LT
Sbjct: 65 IAEMDKECKAFAEESGVSLPDSFSLEQTFHGMFESGGINKPMLKAAVTLRHHGFKTCVLT 124
Query: 124 NTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFL 183
N W+DD +R A+L L HFD ++ESC+ GM KPE QIY + L LKA+P E +FL
Sbjct: 125 NNWIDDSPQRSHSAELFSSLNRHFDLVVESCRTGMRKPETQIYDYALKMLKANPKETIFL 184
Query: 184 DDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVT 243
DDIGANLKPAR++G+ T+LV+DT+TALKEL+ ++G+ L P NP +++HG VT
Sbjct: 185 DDIGANLKPAREMGIATVLVKDTETALKELQALSGVPLFENEEVTPVPANPDNVTHGSVT 244
Query: 244 VKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPP 303
VKP V+LH+VE+G+GP +CLCHGFPESWYSWR+QIPALA AG+RV+A DMKGYG+SSAP
Sbjct: 245 VKPGVQLHYVEMGNGPVICLCHGFPESWYSWRFQIPALADAGFRVIAFDMKGYGDSSAPQ 304
Query: 304 EIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFI 363
EIEEY E +CK++V+FLD +G+SQA FIGHDWGG +VW MALFYPERVRAVASLNTPF
Sbjct: 305 EIEEYSQEQICKDLVSFLDVMGISQASFIGHDWGGAVVWNMALFYPERVRAVASLNTPFF 364
Query: 364 PANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-----SVLS 418
++P ++ LE IKANP+FDYQLYFQEPGVAEAELE++L RTFK FR S E + L+
Sbjct: 365 TSDPGVNALERIKANPIFDYQLYFQEPGVAEAELEKDLERTFKVFFRGSSEKDRLATSLT 424
Query: 419 MHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACK 478
V E GG+ V + E+P LS ++ E ++Q+YV QFKKSGFRGPLNWYRNM+RN +W
Sbjct: 425 TMNVRERGGILVGTDEDPPLSSIINEADLQYYVAQFKKSGFRGPLNWYRNMQRNSEWNIS 484
Query: 479 SLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQIL 538
+ G KIL+PALMVTA KDFVL+P M++ ME+ IP+L RGHIE+C HWTQM++P VN IL
Sbjct: 485 AHGWKILVPALMVTAGKDFVLLPIMTKGMENLIPNLSRGHIEECSHWTQMERPAAVNGIL 544
Query: 539 IKWLDSDARNPPVVSKM 555
IKWL ++ N PV SK+
Sbjct: 545 IKWL-AEVHNLPVTSKL 560
>ref|NP_001028817.1| epoxide hydrolase 2, cytoplasmic [Gallus gallus]
gb|AAZ38461.1| soluble epoxide hydrolase [Gallus gallus]
Length = 562
Score = 682 bits (1760), Expect = 0.0, Method: Composition-based stats.
Identities = 312/548 (56%), Positives = 413/548 (75%), Gaps = 5/548 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M R A+FDL GVL P + LG E + ALPR L D GG + ++M+G+ITL
Sbjct: 1 MARRFALFDLGGVLFGPGLQHFLGSCERSYALPRNFLRDVLFAGGSDSPHAKVMRGQITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQ ++E CR+ + TA + LP FSI +F++ + +N P+L+AA MLR+ GF T
Sbjct: 61 SQLFLEVDEGCRQHASTAGITLPTTFSIAHVFEEMAAKGTLNAPLLRAASMLRRNGFKTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
+ TN W+DD R + L+ ++ HFD LIESC+VG+ KP+P+IY + L+ L+A P EV
Sbjct: 121 VFTNNWVDDSMGRLFTSSLLTVVQRHFDLLIESCRVGLHKPDPRIYTYALEVLQAQPQEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
+FLDDIG NLKPAR++GM TILV+DTDT LKEL++++G+QLL PLPT+C+P+ MSHG
Sbjct: 181 IFLDDIGENLKPAREMGMATILVRDTDTVLKELQELSGVQLLQQEEPLPTTCDPATMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV ++P V+LHFVE+G GPA+CLCHGFPESW SWRYQIPALA AG+RV+A++MKGYGES+
Sbjct: 241 YVPIRPGVQLHFVEMGHGPAICLCHGFPESWLSWRYQIPALADAGFRVIALEMKGYGEST 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY E +CK++ FLDKLG+ QAVFIGHDWGG +VW MALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYSQEQICKDLTIFLDKLGIPQAVFIGHDWGGAVVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD-----ES 415
P+ PA+P + +E++K+ P+FDYQ YFQEPGVAEAELE+++ RT K+L R++ S
Sbjct: 361 PYRPADPTVDIVETMKSFPMFDYQFYFQEPGVAEAELEKDIGRTLKALIRSTRPEDRLHS 420
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
V + V E GGL V PE+ S ++ E+Q+Y+++F++SGFRGPLNWYRNM NW+W
Sbjct: 421 VPGLLGVQERGGLLVGFPEDIPESLILHGAELQYYIERFQRSGFRGPLNWYRNMRPNWRW 480
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 535
A + RKIL+PALMVTA KD VL+P MS+ ME+WIP L+RGH+E CGHWTQM++P +N
Sbjct: 481 ALSAKDRKILMPALMVTAGKDVVLLPSMSKGMEEWIPQLRRGHLEACGHWTQMERPAALN 540
Query: 536 QILIKWLD 543
+IL++WL+
Sbjct: 541 RILVEWLE 548
>ref|NP_001087143.1| epoxide hydrolase 2, cytoplasmic [Xenopus laevis]
gb|AAH78066.1| Ephx2-prov protein [Xenopus laevis]
Length = 560
Score = 676 bits (1743), Expect = 0.0, Method: Composition-based stats.
Identities = 313/557 (56%), Positives = 406/557 (72%), Gaps = 6/557 (1%)
Query: 4 RAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQW 63
R +FDL GVL P R E +L LP G L + F + G EG +G+I S++
Sbjct: 5 RFVLFDLGGVLLTPGPQSAFQRLETSLHLPSGFLQNVFTRSGSEGPFAMAERGKIPFSKF 64
Query: 64 IPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILT 123
+ M + CR +E + V LP++FS+++ F IN+PML+AA+ LR GF T +LT
Sbjct: 65 VAEMNKECRAFAEESGVSLPESFSLEQAFHGMFENGGINKPMLKAAVKLRHHGFKTCVLT 124
Query: 124 NTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFL 183
N W+DD +R A+++ L HFD ++ESC++GM KPE QIY++ L L A P E +FL
Sbjct: 125 NNWIDDSPQRSLSAEVLSSLSRHFDLVVESCRIGMRKPETQIYEYALKLLHAKPKETIFL 184
Query: 184 DDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVT 243
DDIGANLKPAR++G+ T+LV+DT+TALKEL+ ++ + L+ P NP ++HG+VT
Sbjct: 185 DDIGANLKPAREMGIATVLVKDTETALKELQALSNVPLIENEEVAPIPANPDKVTHGFVT 244
Query: 244 VKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPP 303
VKP V+LH+VE+G+GP +CLCHGFPESWYSWR+QIPALA AG+RV+A DMKGYG+SSAP
Sbjct: 245 VKPGVKLHYVEMGNGPVICLCHGFPESWYSWRFQIPALADAGFRVIAFDMKGYGDSSAPH 304
Query: 304 EIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFI 363
EIEEY E +CK++V+FLD LG+SQA FIGHDWGG +VW MALFYPERVRAVASLNTPF
Sbjct: 305 EIEEYSQEQICKDLVSFLDALGISQASFIGHDWGGAVVWNMALFYPERVRAVASLNTPFF 364
Query: 364 PANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-----SVLS 418
+ P ++ LE IKANP+FDYQLYFQEPGVAEAELE+NL RTFK FR S E + L+
Sbjct: 365 TSEPGVNALERIKANPIFDYQLYFQEPGVAEAELEKNLERTFKVFFRGSSEKDRLPTTLT 424
Query: 419 MHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACK 478
V E GG+ V + E+ LS ++ E ++ +YV QFKKSGFRGPLNWYRNM+RN +W+
Sbjct: 425 TMNVRERGGILVGTDEDTPLSSIINEADLHYYVAQFKKSGFRGPLNWYRNMQRNSEWSIS 484
Query: 479 SLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQIL 538
+ G KIL+PALMVTA KDFVL+P M++ ME+ IP+L RGHIE+C HWTQM++P VN+IL
Sbjct: 485 AHGWKILVPALMVTAGKDFVLLPIMTKGMENLIPNLSRGHIEECSHWTQMERPAAVNEIL 544
Query: 539 IKWLDSDARNPPVVSKM 555
IKWL + N PV SK+
Sbjct: 545 IKWL-GEVLNLPVTSKL 560
>emb|CAH91370.1| hypothetical protein [Pongo abelii]
Length = 372
Score = 654 bits (1688), Expect = 0.0, Method: Composition-based stats.
Identities = 307/320 (95%), Positives = 314/320 (98%), Gaps = 1/320 (0%)
Query: 237 MSHGYVTV-KPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKG 295
+ G +T+ +P VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKG
Sbjct: 53 LMRGEITLSQPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKG 112
Query: 296 YGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV 355
YGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV
Sbjct: 113 YGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV 172
Query: 356 ASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES 415
ASLNTPFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES
Sbjct: 173 ASLNTPFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES 232
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
VLSMHKVCEAGGLFV+SPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW
Sbjct: 233 VLSMHKVCEAGGLFVSSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 292
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 535
ACKSLGRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVN
Sbjct: 293 ACKSLGRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 352
Query: 536 QILIKWLDSDARNPPVVSKM 555
QILIKWLDSDARNP VVSKM
Sbjct: 353 QILIKWLDSDARNPLVVSKM 372
Score = 124 bits (310), Expect = 3e-26, Method: Composition-based stats.
Identities = 61/62 (98%), Positives = 62/62 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQ 62
SQ
Sbjct: 61 SQ 62
>ref|XP_001521600.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic, partial
[Ornithorhynchus anatinus]
Length = 530
Score = 617 bits (1591), Expect = e-175, Method: Composition-based stats.
Identities = 298/491 (60%), Positives = 368/491 (74%), Gaps = 24/491 (4%)
Query: 64 IPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILT 123
+PL++E CR S A + LP FSI+ +FD+ S +IN PMLQAA+ LR +G+ T IL+
Sbjct: 2 VPLLDEACRDISAAAGLQLPTPFSIRRVFDEMGSGAEINIPMLQAAIALRNRGWKTGILS 61
Query: 124 NTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFL 183
NTW+DD +R A++ C L HFD +ESC VG+ KP+P IY L+ L P E V L
Sbjct: 62 NTWVDDSPQRGQWAEISCALAKHFDLRVESCHVGVAKPDPGIYLLALEALGVRPHEAVCL 121
Query: 184 DDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTS---------CNP 234
DD ANL+ A +LG+VT+ +DT AL++LE+VTG+Q+ TP P C+P
Sbjct: 122 DDTEANLRAALELGLVTVQARDTAAALEKLEQVTGMQVWTTPVMPPPPLHPLSLAPWCSP 181
Query: 235 SDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMK 294
+ ++P V+LHFVE G+GPAVCLCHGFPESW+SWRYQIPALA AG+RV+A+DMK
Sbjct: 182 P------LPIQPGVQLHFVEAGTGPAVCLCHGFPESWFSWRYQIPALADAGFRVIALDMK 235
Query: 295 GYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRA 354
GYG+SSAP IEEY E +CKE VTFLDKLG+SQAVFIGHDWGGM VW MALFYPERVRA
Sbjct: 236 GYGDSSAPQAIEEYSQEEMCKEAVTFLDKLGISQAVFIGHDWGGMFVWNMALFYPERVRA 295
Query: 355 VASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE 414
VASLNTPF+PA+P++ +E I+A PV DYQLYFQEPGVAEAELE NLSRT K L RASDE
Sbjct: 296 VASLNTPFMPADPSVPAMERIRALPVCDYQLYFQEPGVAEAELEANLSRTLKLLIRASDE 355
Query: 415 SVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWK 474
KV GGL V PE SR++ EE+++FYVQQF+KSGFRGPLNWYRNMERNW+
Sbjct: 356 ------KVGSPGGLLVGMPEFSPTSRILKEEDLRFYVQQFEKSGFRGPLNWYRNMERNWR 409
Query: 475 WACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHL---KRGHIEDCGHWTQMDKP 531
W+C ++GRKI++PALM+TA KD +L PQ S+HMEDW+ +RGHIE+CGHWTQM++P
Sbjct: 410 WSCTAVGRKIMVPALMITAGKDPILTPQTSRHMEDWVRSWGSGERGHIEECGHWTQMERP 469
Query: 532 TEVNQILIKWL 542
TE+NQILIKWL
Sbjct: 470 TELNQILIKWL 480
>ref|NP_001008642.1| epoxide hydrolase 2, cytoplasmic [Danio rerio]
gb|AAH86714.1| Zgc:101645 [Danio rerio]
gb|AAI65172.1| Ephx2 protein [synthetic construct]
Length = 557
Score = 574 bits (1480), Expect = e-162, Method: Composition-based stats.
Identities = 272/543 (50%), Positives = 371/543 (68%), Gaps = 7/543 (1%)
Query: 4 RAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQW 63
+A +F L G + P + + EE + +G + + K G + A R KG+ TL+Q
Sbjct: 3 KAVLFSLWGGVVTPQIGQAFQKFEETTGISKGFIKNVETKLGSDNALHRAEKGKTTLAQM 62
Query: 64 IPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILT 123
IP + C+K + + LP FS +++FD + + N L AA +LR+ G T IL
Sbjct: 63 IPEFDAECQKVAADQGLSLPAQFSTQKLFDD-MGKVEFNMTFLDAAAVLRRNGIATGILA 121
Query: 124 NTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFL 183
N W+DD A+R +A+++ L+ FD ++ SC G+ PEP +K L+ L P E ++L
Sbjct: 122 NIWVDDTAQRGSIARVLSVLESRFDLVLRSCHAGVRIPEPDFFKHALEKLAVKPQEALWL 181
Query: 184 DDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVT 243
D ++K A LG++ + V+D AL E++K+TGI++ T P SC+P +SHGYV
Sbjct: 182 DVDEESVKAAEGLGIMAVQVKDVTEALTEIQKLTGIEV--TSDLQPPSCDPEKVSHGYVN 239
Query: 244 VKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPP 303
+KP V++H+VE+G GP V LCHGFPESW+SWRYQIPALA AG+RVLA DMKGYG S+APP
Sbjct: 240 IKPGVKIHYVEMGDGPPVLLCHGFPESWFSWRYQIPALADAGFRVLAPDMKGYGGSTAPP 299
Query: 304 EIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFI 363
+IEEY E + ++VTFLDK+ ++Q +GHDWGG+LVW MA F+PERVRAVASLNTP
Sbjct: 300 DIEEYSQEQIMLDLVTFLDKMAIAQVTLVGHDWGGVLVWNMAQFHPERVRAVASLNTPLF 359
Query: 364 PANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES----VLSM 419
P +PN +P+E + A P+FDYQ+YFQ+PGVAEAELE+NL RTFK +F +S ++ LS
Sbjct: 360 PVDPNTNPMEKLMAIPIFDYQIYFQKPGVAEAELEKNLKRTFKLMFISSSDTGGFPKLSP 419
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
VC+ GGLFV SP++P S M++ +QFY +Q+ KSGFRGPLNWYRN ERNW+W
Sbjct: 420 AGVCQRGGLFVGSPDDPPRSSMLSVSALQFYTEQYSKSGFRGPLNWYRNYERNWRWMVSR 479
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
KIL+PALMVTA KD VL+P + ME+ IP+L RGHIE+CGHWTQM++P E+N+ILI
Sbjct: 480 PRAKILMPALMVTAGKDPVLLPAFATGMENLIPNLSRGHIEECGHWTQMERPAELNKILI 539
Query: 540 KWL 542
WL
Sbjct: 540 SWL 542
>gb|ACC95977.1| soluble epoxide hydrolase-like protein 1 [Strongylocentrotus
purpuratus]
Length = 562
Score = 486 bits (1251), Expect = e-135, Method: Composition-based stats.
Identities = 246/557 (44%), Positives = 348/557 (62%), Gaps = 13/557 (2%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M +A +FDL GVL P L + E L LP L A +G P+ A R+ +GE T
Sbjct: 5 MKKKAVLFDLGGVLFEPPQ-NALRKYGEQLGLPGSFLEKAMIQGRPDNAFCRMERGESTA 63
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Q+ ++C+ S+ LPK+F+ +FD ++ + + ML A +L++ G TA
Sbjct: 64 RQFAEEFTKDCQTLSKEEGQVLPKDFNASSMFDTFMNIKMVP-DMLNAVSVLKQNGVKTA 122
Query: 121 ILTNTWLDDRAERDGLAQLMCELK-MHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
+TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L L E
Sbjct: 123 AVTNNYIDDREQNSLGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKLGVKAEE 182
Query: 180 VVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSH 239
VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P+ S + + H
Sbjct: 183 AVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVFQEAKPV--SVHHERVPH 240
Query: 240 GYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGES 299
Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A AG+RV+AMDMKGYGES
Sbjct: 241 SYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAAAGFRVIAMDMKGYGES 300
Query: 300 SAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
S PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV AV +
Sbjct: 301 SNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVSAVGGIC 360
Query: 360 TPFIPANPNMSPLESIKANP-VFDYQLYFQEPGVAEAELEQNLSRTFKSLFRAS---DES 415
TPF PAN M+P E+I NP ++DYQLYF E G EAE+E N+ + K+ R E
Sbjct: 361 TPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRPLELKEI 420
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
S+ V GG+ P++ + S ++TE+++Q+YV+QFK G R LNWYR ME NWK+
Sbjct: 421 GFSVAGVRAKGGIMAGIPDDIN-STLLTEDDVQYYVKQFKTCGLRSMLNWYRTMEVNWKF 479
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 535
+++GRK+ +PALMVT D VL P +S+ M+ ++ +L R HIED GHW +++P ++N
Sbjct: 480 NHRAIGRKLYMPALMVTCAWDEVLPPSVSKFMDPFVVNLTRAHIEDSGHWASLEQPKKLN 539
Query: 536 QILIKWLD---SDARNP 549
+IL+ WL+ D+ P
Sbjct: 540 KILVDWLNKVHKDSNRP 556
>emb|CAG00866.1| unnamed protein product [Tetraodon nigroviridis]
Length = 535
Score = 480 bits (1236), Expect = e-133, Method: Composition-based stats.
Identities = 255/544 (46%), Positives = 344/544 (63%), Gaps = 19/544 (3%)
Query: 4 RAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQW 63
+A +F+ GV + GV E+ LP G L+ + +GA +R G +TL Q
Sbjct: 5 KAVLFNFWGVTVPSSPHGVCASLEKKRNLPEGFLSSLASR--KDGAMSRAEVGRLTLCQM 62
Query: 64 IPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISAR-KINRPMLQAALMLRKKGFTTAIL 122
P +E C + ++ LP ++S+ E+ DK A +N +L+ A +LR G+ TA+L
Sbjct: 63 APELEAECVQEAQARAAALPSDWSVAELVDKLREAMLDVNPAVLKMAAVLRSHGYLTAVL 122
Query: 123 TNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVF 182
N W+ D + G A+L+ L HFD +++SC+ G PE ++ L L + + ++
Sbjct: 123 ANHWVHDSGDTQGPARLLSHLGGHFDLVLQSCRTGHRVPEAAMFSAALQHLGVTSQQALW 182
Query: 183 LDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYV 242
LD +K A G+ ILV++ + AL +L TG+Q+ + + P CNP+++SHGYV
Sbjct: 183 LDADEDGVKAAEGEGLKAILVENAEDALSKLALHTGLQVDDAGSHTP-PCNPNEVSHGYV 241
Query: 243 TVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAP 302
++ V+ H+VE+G GP V LCHGFPESWYSWRYQIPALA AG+RVLA+DMKGYGES+AP
Sbjct: 242 AIRDGVKTHYVEMGEGPPVLLCHGFPESWYSWRYQIPALAYAGFRVLALDMKGYGESTAP 301
Query: 303 PEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPF 362
+I EY E +CK + Q +GHDWGG LVW MA F+PERVRA ASLNTP
Sbjct: 302 TDISEYTQEQMCK---------AIPQVTLVGHDWGGALVWSMAQFHPERVRAAASLNTPL 352
Query: 363 IPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLF-RASDESV---LS 418
NP S L I+ +FDYQ+YFQE GVAEAELE+NL RTFK F R S+ + LS
Sbjct: 353 FEFNP--STLRKIQDLGIFDYQVYFQEQGVAEAELEENLERTFKVFFSRGSERDIRPPLS 410
Query: 419 MHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACK 478
VC GGL V PE+ LS M+TE ++QFYV +++ GFR PLNWYR ME N KW+
Sbjct: 411 TAGVCARGGLLVGQPEDVPLSSMLTEADLQFYVSRYRDQGFRRPLNWYRAMEANRKWSSS 470
Query: 479 SLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQIL 538
RK+L+PALMVTA +D VL+P +S+ ME+ IP+L RGHIE+ GHWTQMD+P E N+IL
Sbjct: 471 CPNRKVLVPALMVTAGRDPVLLPSLSEGMENMIPNLSRGHIEESGHWTQMDRPAETNRIL 530
Query: 539 IKWL 542
I WL
Sbjct: 531 IGWL 534
>gb|EAW63550.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_d [Homo sapiens]
Length = 221
Score = 471 bits (1211), Expect = e-131, Method: Composition-based stats.
Identities = 221/221 (100%), Positives = 221/221 (100%)
Query: 310 MEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNM 369
MEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNM
Sbjct: 1 MEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNM 60
Query: 370 SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLF 429
SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLF
Sbjct: 61 SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLF 120
Query: 430 VNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPAL 489
VNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPAL
Sbjct: 121 VNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPAL 180
Query: 490 MVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDK 530
MVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDK
Sbjct: 181 MVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDK 221
>ref|XP_795168.2| PREDICTED: similar to Ephx2-prov protein [Strongylocentrotus
purpuratus]
Length = 507
Score = 459 bits (1181), Expect = e-127, Method: Composition-based stats.
Identities = 225/503 (44%), Positives = 321/503 (63%), Gaps = 12/503 (2%)
Query: 55 KGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRK 114
+GE T Q+ ++C+ S+ LPK+F+ +FD ++ + + ML A +L++
Sbjct: 3 RGESTARQFAEEFTKDCQTLSKEEGQVLPKDFNASSMFDTFMNIKMVP-DMLNAVSVLKQ 61
Query: 115 KGFTTAILTNTWLDDRAERDGLAQLMCELK-MHFDFLIESCQVGMVKPEPQIYKFLLDTL 173
G TA +TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L L
Sbjct: 62 NGVKTAAVTNNYIDDREQNSLGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKL 121
Query: 174 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 233
E VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P+ S +
Sbjct: 122 GVKAEEAVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVFQEAKPV--SVH 179
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
+ H Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A G+RV+AMDM
Sbjct: 180 HERVPHSYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAATGFRVIAMDM 239
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
KGYGESS PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV
Sbjct: 240 KGYGESSNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVS 299
Query: 354 AVASLNTPFIPANPNMSPLESIKANP-VFDYQLYFQEPGVAEAELEQNLSRTFKSLFRAS 412
AV + TPF PAN M+P E+I NP ++DYQLYF E G EAE+E N+ + K+ R
Sbjct: 300 AVGGICTPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRP 359
Query: 413 ---DESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNM 469
E S+ V GG+ P++ + S ++TE+++Q+YV+QFK G R LNWYR M
Sbjct: 360 LELKEIGFSVAGVRAKGGIMAGIPDDIN-STLLTEDDVQYYVKQFKTCGLRSMLNWYRTM 418
Query: 470 ERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMD 529
E NWK+ +++GRK+ +PALMVT D VL P +S+ M+ ++ +L R HIED GHW ++
Sbjct: 419 EVNWKFNHRAIGRKLYMPALMVTCAWDEVLPPSVSKFMDPFVVNLTRAHIEDSGHWASLE 478
Query: 530 KPTEVNQILIKWLD---SDARNP 549
+P ++N+IL+ WL+ D+ P
Sbjct: 479 QPKKLNKILVDWLNKVHKDSNRP 501
>ref|XP_001184789.1| PREDICTED: similar to Ephx2-prov protein [Strongylocentrotus
purpuratus]
Length = 707
Score = 458 bits (1178), Expect = e-127, Method: Composition-based stats.
Identities = 221/489 (45%), Positives = 315/489 (64%), Gaps = 12/489 (2%)
Query: 69 ENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLD 128
++C+ S+ LPK+F+ +FD ++ + + ML A +L++ G TA +TN ++D
Sbjct: 217 KDCQTLSKEEGQVLPKDFNASSMFDTFMNIKMVP-DMLNAVSVLKQNGVKTAAVTNNYID 275
Query: 129 DRAERDGLAQLMCELK-MHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIG 187
DR + A +M L +FD +ESC+ G KP+ I+ L L E VFLDD+G
Sbjct: 276 DREQNSLGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKLGVKAEEAVFLDDLG 335
Query: 188 ANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPR 247
N+K AR++G+ T+LV+DT ALKEL++VTGI + P+ S + + H Y T +
Sbjct: 336 PNVKAAREMGISTVLVKDTSAALKELQEVTGIDVFQEAKPV--SVHHERVPHSYATTRSG 393
Query: 248 VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEE 307
V+ H+V++GSGP V CHGFPESWY W+ QIPA+A G+RV+AMDMKGYGESS PPEIEE
Sbjct: 394 VKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAATGFRVIAMDMKGYGESSNPPEIEE 453
Query: 308 YCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANP 367
Y +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV AV + TPF PAN
Sbjct: 454 YTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVSAVGGICTPFFPAND 513
Query: 368 NMSPLESIKANP-VFDYQLYFQEPGVAEAELEQNLSRTFKSLFRAS---DESVLSMHKVC 423
M+P E+I NP ++DYQLYF E G EAE+E N+ + K+ R E S+ V
Sbjct: 514 TMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRPLELKEIGFSVAGVR 573
Query: 424 EAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRK 483
GG+ P++ + S ++TE+++Q+YV+QFK G R LNWYR ME NWK+ +++GRK
Sbjct: 574 AKGGIMAGIPDDIN-STLLTEDDVQYYVKQFKTCGLRSMLNWYRTMEVNWKFNHRAIGRK 632
Query: 484 ILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLD 543
+ +PALMVT D VL P +S+ M+ ++ +L R HIED GHW +++P ++N+IL+ WL+
Sbjct: 633 LYMPALMVTCAWDEVLPPSVSKFMDPFVVNLTRAHIEDSGHWASLEQPKKLNKILVDWLN 692
Query: 544 ---SDARNP 549
D+ P
Sbjct: 693 KVHKDSNRP 701
>ref|XP_795076.2| PREDICTED: similar to Ephx2-prov protein, partial
[Strongylocentrotus purpuratus]
Length = 492
Score = 425 bits (1092), Expect = e-117, Method: Composition-based stats.
Identities = 225/513 (43%), Positives = 308/513 (60%), Gaps = 32/513 (6%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M +A +FDL GVL P L + E L LP D FQ E T
Sbjct: 5 MKKKAVLFDLGGVLFEPPQ-NALRKYGEQLGLPG---QDLFQ-----------FAEEFT- 48
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
++C+ S+ LPK+F+ +FD ++ + + ML A +L++ G TA
Sbjct: 49 --------KDCQTVSKEEGQVLPKDFNASSMFDTFMNIKMVP-DMLNAVSVLKQNGVKTA 99
Query: 121 ILTNTWLDDRAERDGLAQLMCELK-MHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
+TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L L E
Sbjct: 100 AVTNNYIDDREQNSVGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKLGVKAEE 159
Query: 180 VVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSH 239
VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P+ S + + H
Sbjct: 160 AVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVCQEAKPV--SVHHERVPH 217
Query: 240 GYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGES 299
Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A AG+RV+AMDMKGYGES
Sbjct: 218 SYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAAAGFRVIAMDMKGYGES 277
Query: 300 SAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
S PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV AV +
Sbjct: 278 SNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVSAVGGIC 337
Query: 360 TPFIPANPNMSPLESIKANP-VFDYQLYFQEPGVAEAELEQNLSRTFKSLFRAS---DES 415
TPF PAN M+P E+I NP ++DYQLYF E G EAE+E N+ + K+ R E
Sbjct: 338 TPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRPLELKEI 397
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
S+ V GG+ P++ LS ++TE+++Q+YV+QFK G R LNWYR ME NWK+
Sbjct: 398 GFSVAGVRAKGGIMAGIPDDIKLSTLLTEDDLQYYVKQFKTCGLRSMLNWYRTMEVNWKF 457
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHME 508
+++GRK+ +PALMVT D VL P S+ M+
Sbjct: 458 NHRAIGRKLYMPALMVTCAGDAVLPPSASKFMD 490
>ref|XP_001190554.1| PREDICTED: similar to Ephx2-prov protein [Strongylocentrotus
purpuratus]
Length = 595
Score = 423 bits (1087), Expect = e-116, Method: Composition-based stats.
Identities = 228/532 (42%), Positives = 314/532 (59%), Gaps = 38/532 (7%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M +A +FDL GVL P L + E L LP D FQ E T
Sbjct: 5 MKKKAVLFDLGGVLFEPPQ-NALRKYGEQLGLPG---QDLFQ-----------FAEEFT- 48
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
++C+ S+ LPK+F+ +FD ++ + + ML A +L++ G TA
Sbjct: 49 --------KDCQTVSKEEGQVLPKDFNASSMFDTFMNIKMVP-DMLNAVSVLKQNGVKTA 99
Query: 121 ILTNTWLDDRAERDGLAQLMCELK-MHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
+TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L L E
Sbjct: 100 AVTNNYIDDREQNSVGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKLGVKAEE 159
Query: 180 VVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSH 239
VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P+ S + + H
Sbjct: 160 AVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVCQEAKPV--SVHHERVPH 217
Query: 240 GYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGES 299
Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A AG+RV+AMDMKGYGES
Sbjct: 218 SYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAAAGFRVIAMDMKGYGES 277
Query: 300 SAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
S PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV AV +
Sbjct: 278 SNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVSAVGGIC 337
Query: 360 TPFIPANPNMSPLESIKANP-VFDYQLYFQEPGVAEAELEQNLSRTFKSLFRAS---DES 415
TPF PAN M+P E+I NP ++DYQLYF E G EAE+E N+ + K+ R E
Sbjct: 338 TPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRPLELKEI 397
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
S+ V GG+ P++ LS ++TE+++Q+YV+QFK G R LNWYR ME NWK+
Sbjct: 398 GFSVAGVRAKGGIMAGIPDDIKLSTLLTEDDLQYYVKQFKTCGLRSMLNWYRTMEVNWKF 457
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ 527
+++GRK+ +PALMVT D VL P S+ M+ + + C WT+
Sbjct: 458 NHRAIGRKLYMPALMVTCAGDAVLPPSASKFMDPF------SRCKLCSDWTR 503
>ref|XP_001641873.1| predicted protein [Nematostella vectensis]
gb|EDO49810.1| predicted protein [Nematostella vectensis]
Length = 548
Score = 403 bits (1035), Expect = e-110, Method: Composition-based stats.
Identities = 220/554 (39%), Positives = 330/554 (59%), Gaps = 32/554 (5%)
Query: 3 LRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQ 62
+ A+FDL GV+A F + + +P LL F +L G+I+LSQ
Sbjct: 2 FKLAIFDLGGVVATSLKFAI-EHYAWKMGVPYSLLQKLFLPSNENQPMWQLETGKISLSQ 60
Query: 63 WIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAIL 122
+ E +E + LP FS+K +FD+ K+ ML AA L+ GF T I+
Sbjct: 61 FFVSASELISNLAEEEGIKLPPRFSLKTLFDQLYKTIKVVPEMLNAAAALKANGFRTCIV 120
Query: 123 TNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVF 182
+N W DD ++ L ++ +FD ESC++G+ KP+P++YK + K P+EV+F
Sbjct: 121 SNNWTDDTETGQHVSGLSL-IRPYFDDFFESCKIGIRKPDPEMYKLVCKKFKVQPNEVLF 179
Query: 183 LDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNT-PAPLPTSCNPSDMSHGY 241
LDD+ +NL PA+++GM TILV+D +AL+ ++++TGI +L P P +C PS + H
Sbjct: 180 LDDLPSNLAPAKEMGMATILVKDPISALRTVKEITGIDVLKAYPTP---ACTPSSVPHSI 236
Query: 242 VTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSA 301
V +K + +H+V++G G + L HGFPE WY W+YQ ++ Y VL A
Sbjct: 237 VQLKTGIMMHYVDIGHGHPIILLHGFPELWYIWKYQGTIIS---YGVLF---------EA 284
Query: 302 PPEIEEYCMEVL---------CKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERV 352
+ + C ++L +++++ +D L L Q IGHDWGGM+ W +AL +P+R+
Sbjct: 285 KSDAKLACTQLLYSPSDKIIVFQDIISLMDLLLLRQVAVIGHDWGGMVAWDLALHHPDRI 344
Query: 353 RAVASLNTPFIPANPNMSPLESIKANP-VFDYQLYFQEPGVAEAELEQNLSRTFKSLFRA 411
RAVA++ TPF+P NP+++PL +KA P VF YQLYF + G EAE E++L RTFK R
Sbjct: 345 RAVANM-TPFMPPNPDINPLLGLKAKPGVFQYQLYFHQEGPPEAEFEKDLRRTFKLFLRN 403
Query: 412 SDES---VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRN 468
+ E LS V E GG FV +PE+ S M+TEE++ ++V+ F+K+GFRGPLNWYRN
Sbjct: 404 ASEMEQIKLSTSDVLERGGFFVGTPEKVERSCMITEEDLDYFVENFRKTGFRGPLNWYRN 463
Query: 469 MERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQM 528
ME +WKW K RKIL P LM+T+ KD V++P + +M +P+L HIE+ H+T +
Sbjct: 464 MEVDWKWNLKIHPRKILQPVLMITSGKDPVILPAFAANMGAHVPNLSLAHIEESSHFTPI 523
Query: 529 DKPTEVNQILIKWL 542
D+P E+N +L+ WL
Sbjct: 524 DRPLELNNMLLDWL 537
>gb|ACC95978.1| soluble epoxide hydrolase-like protein 2 [Strongylocentrotus
purpuratus]
Length = 561
Score = 328 bits (841), Expect = 8e-88, Method: Composition-based stats.
Identities = 195/557 (35%), Positives = 298/557 (53%), Gaps = 32/557 (5%)
Query: 4 RAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQW 63
+ +FDL GV+ P +L EEA LPR + + +G RL +GEIT++Q+
Sbjct: 5 KVVLFDLGGVIVTPPQRALLKYCEEA-GLPRNFIFNVISQGRANNTFARLERGEITVTQF 63
Query: 64 IPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILT 123
E+ CR+ +E + +P +FS E+ + + ML A +L++ G T LT
Sbjct: 64 ATEFEQECRRVAEAQSLVIPDSFSATEMVN--FKDPDLIPEMLNAVAVLKENGVQTCALT 121
Query: 124 NTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFL 183
N ++D+ + R A + +FD +ESC++G+ KP+P I+ L L A S+ VFL
Sbjct: 122 NNYIDNTSNRAYAAGGLTAFTFYFDEFVESCRLGIRKPDPNIFHEALARLGAEASQAVFL 181
Query: 184 DDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVT 243
DD N K A LG+ +ILVQD TAL++L+ VTGI + P+ + +P +++H YVT
Sbjct: 182 DDSEVNTKAAEALGITSILVQDPKTALEQLKIVTGIDVFKQAGPI--TVHPDEVTHSYVT 239
Query: 244 VKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPP 303
+ +VR HF ELGSGP V LCH F E W +WR +P LA AG+R +A+D+KG+GESS P
Sbjct: 240 TRSKVRFHFTELGSGPPVVLCHDFEEDWEAWRSLMPELAIAGFRAIALDLKGFGESSKPT 299
Query: 304 EIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFI 363
+ E+Y +++LC++M FLD LG++Q IG G W A +RVRAVA +NT
Sbjct: 300 DTEQYTLKILCRDMTEFLDALGIAQVTLIGKGMGSAFAWTFANHTTDRVRAVAGINTSPS 359
Query: 364 PANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRA----SDESVLSM 419
P+ + IK + F+ + N + +R S ++ +
Sbjct: 360 VVIPDTLYGDQIKRIGSLQDYIKFRH---CDRNNNNNPDIEMEQFYRIATCHSSDTNPTK 416
Query: 420 HKVCEAGGLFVNSPE---EPSLSRMVTEEEIQFYVQ-------QFKKSGFRGPLNWYRNM 469
H C G+ V E + S++ + E + + Q KS RG NW+RN
Sbjct: 417 HDRC-LQGIDVKDFELSTKASMNCLCIEADKRGKKQLGGHHRSTKSKSKSRGA-NWFRNN 474
Query: 470 ERNWKWACKSLGRKILIPALMVT----AEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHW 525
NW+W + GR +LIPAL+VT + KD VP +S+ ++ WIP ++ H+ C
Sbjct: 475 AANWEWNRRLNGRMLLIPALVVTSGQGSPKD---VPDVSE-LKKWIPEVEHSHVSGCEIK 530
Query: 526 TQMDKPTEVNQILIKWL 542
T ++ +E+N+IL KWL
Sbjct: 531 TDRERSSELNRILRKWL 547
>ref|XP_001253507.1| PREDICTED: hypothetical protein [Bos taurus]
Length = 177
Score = 290 bits (742), Expect = 2e-76, Method: Composition-based stats.
Identities = 127/167 (76%), Positives = 154/167 (92%)
Query: 389 EPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQ 448
EPGVAEAELE+NLSRTFKS FR++DE+ +++ + CE GGL VN+PEEP+LS+MVTEE+IQ
Sbjct: 11 EPGVAEAELEKNLSRTFKSFFRSNDETFITVSRTCEMGGLLVNTPEEPTLSKMVTEEDIQ 70
Query: 449 FYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHME 508
FYVQ+FKKSGFRGPLNWYRNM++NW+W K GRKILIPALMVTAEKD VL P+MS+HME
Sbjct: 71 FYVQEFKKSGFRGPLNWYRNMDKNWEWGFKGSGRKILIPALMVTAEKDLVLTPEMSKHME 130
Query: 509 DWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM 555
DWIPHLKRGHI+DCGHWTQM+KPTE+N+ILI+WL++DAR+ PVVSK+
Sbjct: 131 DWIPHLKRGHIKDCGHWTQMEKPTELNRILIEWLETDARDLPVVSKL 177
>ref|XP_001181957.1| PREDICTED: similar to soluble epoxide hydrolase, partial
[Strongylocentrotus purpuratus]
Length = 527
Score = 266 bits (680), Expect = 4e-69, Method: Composition-based stats.
Identities = 129/322 (40%), Positives = 192/322 (59%), Gaps = 4/322 (1%)
Query: 39 DAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISA 98
+ +G RL +GEIT++Q+ E+ CR+ +E + +P +FS E+ +
Sbjct: 5 NVISQGRANNTFARLERGEITVTQFATEFEQECRRVAEAQSLVIPDSFSATEMVN--FKD 62
Query: 99 RKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGM 158
+ ML A +L++ G T LTN ++D+ + R A + +FD +ESC++G+
Sbjct: 63 PDLIPEMLNAVAVLKENGVQTCALTNNYIDNTSNRAYAAGGLTAFTFYFDEFVESCRLGI 122
Query: 159 VKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTG 218
KP+P I+ L L A S+ VFLDD N K A LG+ +ILVQD TAL++L+ VTG
Sbjct: 123 RKPDPNIFHEALARLGAEASQAVFLDDSEVNTKAAEALGITSILVQDPKTALEQLKIVTG 182
Query: 219 IQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQI 278
I + P+ + +P +++H YVT + +VR HF ELGSGP V LCH F E W +WR +
Sbjct: 183 IDVFKQAGPI--TVHPDEVTHSYVTTRSKVRFHFTELGSGPPVVLCHDFEEDWEAWRSLM 240
Query: 279 PALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGG 338
P LA AG+R +A+D+KG+GESS P + E+Y +++LC++M FLD LG++Q IG G
Sbjct: 241 PELAIAGFRAIALDLKGFGESSKPTDTEQYTLKILCRDMTEFLDALGIAQVTLIGKGMGS 300
Query: 339 MLVWYMALFYPERVRAVASLNT 360
W A +RVRAVA +NT
Sbjct: 301 AFAWTFANHTTDRVRAVAGINT 322
Score = 70.5 bits (171), Expect = 3e-10, Method: Composition-based stats.
Identities = 38/91 (41%), Positives = 56/91 (61%), Gaps = 9/91 (9%)
Query: 456 KSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVT----AEKDFVLVPQMSQHMEDWI 511
KS RG NW+RN NW+W + GR +LIPAL+VT + KD VP +S+ ++ WI
Sbjct: 428 KSKSRGA-NWFRNNAANWEWNRRLNGRMLLIPALVVTSGQGSPKD---VPDVSE-LKKWI 482
Query: 512 PHLKRGHIEDCGHWTQMDKPTEVNQILIKWL 542
P ++ H+ C T ++ +E+N+IL KWL
Sbjct: 483 PEVEHSHVSGCEIKTDRERSSELNRILRKWL 513
>ref|YP_486290.1| Alpha/beta hydrolase [Rhodopseudomonas palustris HaA2]
gb|ABD07379.1| Alpha/beta hydrolase [Rhodopseudomonas palustris HaA2]
Length = 315
Score = 239 bits (609), Expect = 6e-61, Method: Composition-based stats.
Identities = 135/301 (44%), Positives = 178/301 (59%), Gaps = 7/301 (2%)
Query: 248 VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEE 307
+ L E G GP V LCHG+PE YSWR+QIPALA AGYRV+A DM+G+G SSAP IE
Sbjct: 12 IELFLRERGEGPLVLLCHGWPELSYSWRHQIPALADAGYRVVAPDMRGFGRSSAPHPIEA 71
Query: 308 YCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANP 367
Y + L +MV + +L ++AV IGHDWG + W+ ALF PE AVA L+ P P
Sbjct: 72 YSIFDLVGDMVALVAELKETRAVIIGHDWGAPVAWHAALFRPELFTAVAGLSVP-PPWRG 130
Query: 368 NMSPLESIKANPVFD-YQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 426
PL+ + A V + Y YFQ PGVAEAE E++++ T + + V E
Sbjct: 131 KGRPLDLLSAAGVTNFYWQYFQTPGVAEAEFERDVTATIRGMLCGGFSDPTRSLFVPEGR 190
Query: 427 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 486
G S L ++E E+ F+++Q+K+SGFRG LNWYRN++RNW G +I
Sbjct: 191 GFIGRSASSLPLPSWLSETELAFFIEQYKESGFRGGLNWYRNIDRNWDLTAPWDGAQIRQ 250
Query: 487 PALMVTAEKDFVLVPQMS-QH---MEDWIPHLKRGHIED-CGHWTQMDKPTEVNQILIKW 541
PAL + KD V+ +MS +H ME +P+LKR I D GHW Q +KP EVN LI +
Sbjct: 251 PALFIAGSKDPVISDKMSGKHVAAMERVLPNLKRKLIIDGAGHWIQQEKPAEVNAALIDF 310
Query: 542 L 542
L
Sbjct: 311 L 311
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|XP_001163779.1| PREDICTED: epoxide hydrolase 2, cytopla... 919 0.0
ref|NP_001970.2| epoxide hydrolase 2, cytoplasmic [Homo sap... 918 0.0
gb|AAP36260.1| Homo sapiens epoxide hydrolase 2, cytoplasmi... 918 0.0
gb|AAG14967.1|AF233335_1 soluble epoxide hydrolase [Homo sa... 916 0.0
gb|AAG14968.1|AF233336_1 soluble epoxide hydrolase [Homo sa... 914 0.0
gb|EAW63547.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 911 0.0
ref|XP_001163896.1| PREDICTED: epoxide hydrolase 2, cytopla... 905 0.0
gb|AAA02756.1| cytosolic epoxide hydrolase 905 0.0
ref|XP_001109474.1| PREDICTED: similar to epoxide hydrolase... 888 0.0
ref|NP_001069002.1| epoxide hydrolase 2, cytoplasmic [Bos t... 849 0.0
ref|XP_001163527.1| PREDICTED: epoxide hydrolase 2, cytopla... 845 0.0
gb|EAW63549.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 844 0.0
ref|NP_001001641.1| soluble epoxide hydrolase [Sus scrofa] ... 841 0.0
ref|XP_534566.1| PREDICTED: similar to epoxide hydrolase 2,... 838 0.0
ref|XP_857471.1| PREDICTED: similar to epoxide hydrolase 2,... 837 0.0
ref|XP_001492725.1| PREDICTED: similar to soluble epoxide h... 836 0.0
ref|XP_001163861.1| PREDICTED: epoxide hydrolase 2, cytopla... 834 0.0
ref|XP_857554.1| PREDICTED: similar to epoxide hydrolase 2,... 832 0.0
ref|XP_857430.1| PREDICTED: similar to epoxide hydrolase 2,... 830 0.0
ref|XP_001163819.1| PREDICTED: epoxide hydrolase 2, cytopla... 826 0.0
gb|EAW63551.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 822 0.0
ref|XP_001163565.1| PREDICTED: epoxide hydrolase 2, cytopla... 821 0.0
ref|NP_075225.1| epoxide hydrolase 2, cytoplasmic [Rattus n... 815 0.0
gb|AAH85732.1| Epoxide hydrolase 2, cytoplasmic [Rattus nor... 814 0.0
emb|CAA85471.1| Epoxide Hydrolase [Mus musculus] 813 0.0
ref|NP_031966.2| epoxide hydrolase 2, cytoplasmic [Mus musc... 812 0.0
dbj|BAE25172.1| unnamed protein product [Mus musculus] 812 0.0
gb|EDL85377.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 761 0.0
ref|XP_001380051.1| PREDICTED: similar to soluble epoxide h... 753 0.0
ref|NP_001087143.1| epoxide hydrolase 2, cytoplasmic [Xenop... 753 0.0
ref|NP_001006912.1| epoxide hydrolase 2, cytoplasmic [Xenop... 752 0.0
gb|EDL36006.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 752 0.0
gb|AAM28238.1| ovary-selective epoxide hydrolase [Mus muscu... 739 0.0
gb|ABU95055.1| epoxide hydrolase 2C [Mus musculus] 731 0.0
ref|NP_001028817.1| epoxide hydrolase 2, cytoplasmic [Gallu... 709 0.0
ref|NP_001008642.1| epoxide hydrolase 2, cytoplasmic [Danio... 671 0.0
gb|ACC95977.1| soluble epoxide hydrolase-like protein 1 [St... 663 0.0
ref|XP_001521600.1| PREDICTED: similar to epoxide hydrolase... 614 e-174
emb|CAG00866.1| unnamed protein product [Tetraodon nigrovir... 592 e-167
ref|XP_795168.2| PREDICTED: similar to Ephx2-prov protein [... 591 e-167
ref|XP_795076.2| PREDICTED: similar to Ephx2-prov protein, ... 581 e-164
ref|XP_001190554.1| PREDICTED: similar to Ephx2-prov protei... 581 e-164
ref|XP_001184789.1| PREDICTED: similar to Ephx2-prov protei... 581 e-164
ref|XP_001641873.1| predicted protein [Nematostella vectens... 557 e-156
gb|ACC95978.1| soluble epoxide hydrolase-like protein 2 [St... 509 e-142
emb|CAH91370.1| hypothetical protein [Pongo abelii] 498 e-139
ref|XP_001181957.1| PREDICTED: similar to soluble epoxide h... 467 e-129
ref|YP_629896.1| putative epoxide hydrolase [Myxococcus xan... 358 6e-97
gb|EEJ94100.1| predicted hydrolase or acyltransferase of al... 356 2e-96
ref|NP_771160.1| epoxide hydrolase [Bradyrhizobium japonicu... 356 4e-96
ref|YP_486290.1| Alpha/beta hydrolase [Rhodopseudomonas pal... 352 4e-95
ref|NP_767754.1| epoxide hydrolase [Bradyrhizobium japonicu... 352 5e-95
dbj|BAD13534.1| soluble epoxide hydrolase [Citrus jambhiri] 350 2e-94
ref|ZP_02299346.1| alpha/beta hydrolase fold [Rhodopseudomo... 349 4e-94
ref|NP_948116.1| epoxide hydrolase [Rhodopseudomonas palust... 347 1e-93
ref|NP_821315.1| epoxide hydrolase [Streptomyces avermitili... 346 2e-93
ref|YP_569843.1| alpha/beta hydrolase fold [Rhodopseudomona... 345 7e-93
ref|NP_567228.1| epoxide hydrolase, putative [Arabidopsis t... 344 1e-92
emb|CAO44814.1| unnamed protein product [Vitis vinifera] 344 1e-92
ref|NP_824987.1| epoxide hydrolase [Streptomyces avermitili... 343 2e-92
ref|YP_001853373.1| epoxide hydrolase EphA [Mycobacterium m... 343 2e-92
ref|YP_907699.1| epoxide hydrolase EphA [Mycobacterium ulce... 343 2e-92
emb|CAO17500.1| unnamed protein product [Vitis vinifera] 343 2e-92
ref|NP_959380.1| EphA [Mycobacterium avium subsp. paratuber... 342 4e-92
gb|ABN08020.1| Epoxide hydrolase [Medicago truncatula] 342 4e-92
ref|YP_001310928.1| alpha/beta hydrolase fold [Clostridium ... 342 4e-92
gb|ABK21215.1| unknown [Picea sitchensis] 342 5e-92
ref|NP_001042621.1| Os01g0255000 [Oryza sativa (japonica cu... 341 1e-91
ref|YP_001240076.1| Putative epoxide hydrolase [Bradyrhizob... 339 3e-91
gb|ABK93786.1| unknown [Populus trichocarpa] 339 3e-91
emb|CAO44811.1| unnamed protein product [Vitis vinifera] 339 3e-91
ref|YP_001205815.1| epoxide hydrolase [Bradyrhizobium sp. O... 338 7e-91
dbj|BAA09852.1| Epoxide hydrolase [Glycine max] >gi|2764804... 337 1e-90
ref|YP_879819.1| hydrolase, alpha/beta fold family protein ... 337 1e-90
emb|CAG44464.1| putative epoxide hydrolase [Streptomyces ri... 337 2e-90
emb|CAO44812.1| unnamed protein product [Vitis vinifera] 337 2e-90
emb|CAO40040.1| unnamed protein product [Vitis vinifera] 336 2e-90
emb|CAA55294.1| epoxide hydrolase [Glycine max] 336 2e-90
ref|YP_001413763.1| alpha/beta hydrolase fold [Parvibaculum... 336 3e-90
ref|NP_190669.1| epoxide hydrolase, putative [Arabidopsis t... 336 4e-90
ref|XP_001753609.1| predicted protein [Physcomitrella paten... 334 9e-90
ref|NP_187211.1| epoxide hydrolase, putative [Arabidopsis t... 334 1e-89
ref|ZP_01618404.1| epoxide hydrolase [marine gamma proteoba... 334 1e-89
gb|ABN08024.1| Epoxide hydrolase [Medicago truncatula] 334 1e-89
ref|NP_218134.1| PROBABLE EPOXIDE HYDROLASE EPHA (EPOXIDE H... 334 1e-89
emb|CAO70601.1| unnamed protein product [Vitis vinifera] 334 2e-89
ref|YP_692156.1| hydrolase, alpha/beta fold family [Alcaniv... 333 2e-89
gb|EAW63550.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 333 2e-89
emb|CAN77654.1| hypothetical protein [Vitis vinifera] 332 7e-89
gb|ABN08021.1| Epoxide hydrolase [Medicago truncatula] 331 9e-89
gb|AAM28292.1| epoxide hydrolase [Ananas comosus] 331 9e-89
ref|YP_781780.1| alpha/beta hydrolase fold [Rhodopseudomona... 331 1e-88
ref|YP_761108.1| putative epoxide hydrolase [Hyphomonas nep... 330 2e-88
ref|NP_420043.1| epoxide hydrolase [Caulobacter crescentus ... 330 2e-88
ref|YP_001803894.1| unknown [Cyanothece sp. ATCC 51142] >gi... 330 2e-88
ref|YP_001683228.1| alpha/beta hydrolase fold [Caulobacter ... 329 3e-88
ref|YP_001204572.1| putative epoxide hydrolase [Bradyrhizob... 327 2e-87
ref|YP_703564.1| probable epoxide hydrolase [Rhodococcus sp... 326 2e-87
ref|ZP_00877473.1| COG0596: Predicted hydrolases or acyltra... 325 5e-87
ref|NP_354796.1| epoxide hydrolase [Agrobacterium tumefacie... 325 6e-87
emb|CAD30841.1| soluble epoxide hydrolase [Brassica napus] 325 8e-87
ref|YP_001701281.1| Probable epoxide hydrolase EphA [Mycoba... 324 9e-87
gb|AAA81890.1| epoxide hydrolase 324 1e-86
gb|AAO27849.1|AF482450_1 soluble epoxide hydrolase [Euphorb... 324 1e-86
ref|NP_356953.2| epoxide hydrolase [Agrobacterium tumefacie... 323 2e-86
gb|ABK94011.1| unknown [Populus trichocarpa] 323 3e-86
emb|CAJ19276.1| putative epoxide hydrolase [Solanum commers... 322 7e-86
ref|YP_586462.1| alpha/beta hydrolase fold [Ralstonia metal... 321 8e-86
ref|YP_002769440.1| epoxide hydrolase [Rhodococcus erythrop... 321 1e-85
ref|YP_641931.1| alpha/beta hydrolase fold [Mycobacterium s... 320 2e-85
ref|NP_001051780.1| Os03g0829100 [Oryza sativa (japonica cu... 320 2e-85
ref|NP_001042622.1| Os01g0255100 [Oryza sativa (japonica cu... 319 3e-85
emb|CAO48291.1| unnamed protein product [Vitis vinifera] 319 3e-85
ref|ZP_00108314.1| COG0596: Predicted hydrolases or acyltra... 319 3e-85
ref|YP_890327.1| epoxide hydrolase [Mycobacterium smegmatis... 319 3e-85
ref|NP_627771.1| epoxide hydrolase [Streptomyces coelicolor... 319 4e-85
ref|YP_001073412.1| alpha/beta hydrolase fold [Mycobacteriu... 319 4e-85
gb|EAZ11286.1| hypothetical protein OsJ_001111 [Oryza sativ... 319 5e-85
ref|YP_001238893.1| putative epoxide hydrolase [Bradyrhizob... 318 7e-85
ref|ZP_01615162.1| EphA [marine gamma proteobacterium HTCC2... 317 1e-84
ref|YP_002780595.1| epoxide hydrolase [Rhodococcus opacus B... 317 1e-84
ref|YP_001828370.1| putative epoxide hydrolase [Streptomyce... 317 2e-84
ref|YP_001614793.1| putative hydrolase of unknown specifici... 317 2e-84
ref|ZP_02940345.1| alpha/beta hydrolase fold [Cyanothece sp... 317 2e-84
ref|ZP_01728131.1| Alpha/beta hydrolase fold protein [Cyano... 316 2e-84
ref|YP_002767073.1| epoxide hydrolase [Rhodococcus erythrop... 316 4e-84
ref|ZP_01621577.1| hypothetical protein L8106_23540 [Lyngby... 316 4e-84
pdb|2CJP|A Chain A, Structure Of Potato (Solanum Tuberosum)... 316 5e-84
ref|YP_001132685.1| alpha/beta hydrolase fold [Mycobacteriu... 315 8e-84
gb|AAA81892.1| epoxide hydrolase 315 8e-84
gb|EAY92418.1| hypothetical protein OsI_013651 [Oryza sativ... 314 9e-84
gb|AAA81889.1| epoxide hydrolase 314 1e-83
ref|YP_321204.1| Alpha/beta hydrolase fold [Anabaena variab... 314 1e-83
gb|ACO95125.1| epoxide hydrolase [uncultured organism] 314 1e-83
ref|NP_823281.1| epoxide hydrolase [Streptomyces avermitili... 314 2e-83
ref|YP_001890397.1| alpha/beta hydrolase fold [Burkholderia... 314 2e-83
ref|XP_001098374.1| PREDICTED: similar to abhydrolase domai... 313 2e-83
ref|NP_001069323.2| abhydrolase domain containing 7 [Bos ta... 313 2e-83
ref|XP_001275970.1| epoxide hydrolase [Aspergillus clavatus... 313 2e-83
ref|NP_001051781.1| Os03g0829200 [Oryza sativa (japonica cu... 313 2e-83
ref|YP_001515531.1| hydrolase, alpha/beta fold family [Acar... 313 3e-83
ref|YP_956150.1| alpha/beta hydrolase fold [Mycobacterium v... 312 6e-83
ref|NP_488261.1| hypothetical protein all4221 [Nostoc sp. P... 311 8e-83
ref|YP_260055.1| ephA [Pseudomonas fluorescens Pf-5] >gi|68... 311 8e-83
dbj|BAC11230.1| unnamed protein product [Homo sapiens] 311 8e-83
sp|Q8IUS5|ABHD7_HUMAN Abhydrolase domain-containing protein... 311 8e-83
ref|XP_001377064.1| PREDICTED: similar to abhydrolase domai... 311 9e-83
ref|NP_001067364.1| Os12g0636400 [Oryza sativa (japonica cu... 311 9e-83
gb|AAA81891.1| epoxide hydrolase 311 1e-82
ref|NP_775838.2| abhydrolase domain containing 7 [Homo sapi... 311 1e-82
ref|XP_422345.2| PREDICTED: similar to Abhydrolase domain c... 311 2e-82
ref|XP_001152592.1| PREDICTED: abhydrolase domain containin... 310 2e-82
sp|Q6IE26|ABHD7_MOUSE Abhydrolase domain-containing protein... 310 2e-82
ref|YP_568956.1| alpha/beta hydrolase fold [Rhodopseudomona... 310 2e-82
ref|NP_001001804.2| epoxide hydrolase-related [Mus musculus... 310 2e-82
gb|AAA81893.1| epoxide hydrolase 310 3e-82
ref|ZP_03874491.1| predicted hydrolase or acyltransferase o... 309 3e-82
ref|YP_001545639.1| alpha/beta hydrolase fold [Herpetosipho... 309 3e-82
gb|EDL20166.1| abhydrolase domain containing 7 [Mus musculus] 309 3e-82
ref|ZP_02976857.1| alpha/beta hydrolase fold [Cyanothece sp... 309 3e-82
ref|XP_001475646.1| PREDICTED: similar to epoxide hydrolase... 309 5e-82
ref|NP_769521.1| epoxide hydrolase [Bradyrhizobium japonicu... 308 6e-82
ref|YP_531536.1| alpha/beta hydrolase fold [Rhodopseudomona... 308 8e-82
ref|YP_001704492.1| Probable epoxide hydrolase EphA [Mycoba... 308 1e-81
ref|NP_001055069.1| Os05g0273800 [Oryza sativa (japonica cu... 307 1e-81
ref|ZP_01864318.1| putative epoxide hydrolase [Erythrobacte... 307 1e-81
ref|YP_476608.1| hydrolase, alpha/beta fold family [Synecho... 307 2e-81
ref|ZP_01690851.1| epoxide hydrolase 2 [Microscilla marina ... 306 2e-81
ref|ZP_01629817.1| Alpha/beta hydrolase fold protein [Nodul... 306 2e-81
ref|XP_001261159.1| epoxide hydrolase [Neosartorya fischeri... 305 4e-81
ref|XP_001179361.1| PREDICTED: similar to soluble epoxide h... 305 5e-81
ref|NP_866425.1| probable ephA protein-Mycobacterium tuberc... 305 7e-81
ref|ZP_01617969.1| putative epoxide hydrolase [marine gamma... 304 9e-81
ref|XP_694838.2| PREDICTED: hypothetical protein [Danio rerio] 304 1e-80
ref|ZP_01717897.1| probable ephA protein-Mycobacterium tube... 304 2e-80
ref|YP_954785.1| alpha/beta hydrolase fold [Mycobacterium v... 303 2e-80
gb|ABK24656.1| unknown [Picea sitchensis] 302 6e-80
ref|YP_473962.1| hydrolase, alpha/beta fold family [Synecho... 301 8e-80
ref|NP_193331.3| epoxide hydrolase, putative [Arabidopsis t... 301 1e-79
ref|XP_547281.2| PREDICTED: similar to abhydrolase domain c... 301 1e-79
ref|YP_001859441.1| alpha/beta hydrolase fold protein [Burk... 300 2e-79
gb|ABL97724.1| epoxide hydrolase [uncultured marine bacteri... 300 2e-79
gb|EAY92419.1| hypothetical protein OsI_013652 [Oryza sativ... 300 2e-79
gb|EAY73347.1| hypothetical protein OsI_001194 [Oryza sativ... 300 2e-79
emb|CAG05638.1| unnamed protein product [Tetraodon nigrovir... 299 5e-79
ref|NP_180242.1| ATSEH (Arabidopsis thaliana soluble epoxid... 299 6e-79
ref|YP_001828469.1| putative epoxide hydrolase [Streptomyce... 298 8e-79
ref|YP_954781.1| alpha/beta hydrolase fold [Mycobacterium v... 297 1e-78
ref|XP_001402257.1| hypothetical protein An04g09000 [Asperg... 297 2e-78
ref|YP_001851161.1| epoxide hydrolase EphB [Mycobacterium m... 297 2e-78
ref|NP_388739.1| hypothetical protein BSU08590 [Bacillus su... 296 4e-78
ref|ZP_01115718.1| probable ephA protein-Mycobacterium tube... 295 6e-78
ref|YP_001543763.1| alpha/beta hydrolase fold [Herpetosipho... 295 7e-78
ref|YP_611899.1| alpha/beta hydrolase fold [Silicibacter sp... 294 1e-77
gb|ABL97491.1| putative epoxide hydrolase [uncultured marin... 294 1e-77
ref|ZP_02185384.1| hypothetical protein CAT7_04257 [Carnoba... 294 1e-77
ref|YP_444434.1| hydrolase, alpha/beta fold family, putativ... 293 2e-77
ref|ZP_01014743.1| putative epoxide hydrolase [Rhodobactera... 293 3e-77
ref|YP_137702.1| epoxide hydrolase-related protein [Haloarc... 292 4e-77
pdb|2E3J|A Chain A, The Crystal Structure Of Epoxide Hydrol... 292 5e-77
pdb|2ZJF|A Chain A, Crystal Structure Of Mycobacterium Tube... 292 5e-77
ref|NP_216454.1| PROBABLE EPOXIDE HYDROLASE EPHB (EPOXIDE H... 292 6e-77
gb|EEH35520.1| epoxide hydrolase [Paracoccidioides brasilie... 292 6e-77
ref|YP_001277175.1| alpha/beta hydrolase fold [Roseiflexus ... 291 9e-77
ref|YP_001519646.1| alpha/beta hydrolase fold [Acaryochlori... 291 9e-77
ref|YP_001432538.1| alpha/beta hydrolase fold [Roseiflexus ... 290 2e-76
ref|XP_001239812.1| hypothetical protein CIMG_09433 [Coccid... 289 4e-76
ref|NP_681708.1| putative hydrolase [Thermosynechococcus el... 289 5e-76
ref|YP_001189322.1| alpha/beta hydrolase fold [Pseudomonas ... 288 7e-76
gb|EEH44735.1| epoxide hydrolase [Paracoccidioides brasilie... 287 1e-75
ref|YP_758097.1| alpha/beta hydrolase fold [Maricaulis mari... 287 1e-75
ref|YP_906638.1| epoxide hydrolase EphB [Mycobacterium ulce... 287 2e-75
ref|XP_001493089.1| PREDICTED: similar to abhydrolase domai... 287 2e-75
ref|YP_174259.1| hypothetical protein ABC0759 [Bacillus cla... 286 3e-75
emb|CAB46034.1| putative epoxide hydrolase [Arabidopsis tha... 285 4e-75
ref|NP_180243.1| epoxide hydrolase, putative [Arabidopsis t... 285 5e-75
ref|NP_001072430.1| hydrolase (3B446) [Xenopus tropicalis] ... 285 5e-75
ref|YP_002785957.1| putative hydrolase, alpha/beta fold fam... 285 7e-75
ref|XP_588758.3| PREDICTED: similar to ACAD 10 [Bos taurus] 284 1e-74
ref|YP_001682147.1| alpha/beta hydrolase fold [Caulobacter ... 284 1e-74
ref|YP_001485500.1| possible alpha/beta family hydrolase [B... 284 1e-74
ref|NP_001064967.1| Os10g0498300 [Oryza sativa (japonica cu... 284 2e-74
ref|YP_001753313.1| alpha/beta hydrolase fold [Methylobacte... 284 2e-74
ref|XP_001674008.1| Hypothetical protein CBG09592 [Caenorha... 283 2e-74
ref|YP_001614132.1| Epoxide hydrolase [Sorangium cellulosum... 283 2e-74
ref|YP_722358.1| alpha/beta hydrolase fold [Trichodesmium e... 283 3e-74
ref|NP_497268.1| K02F3.6 [Caenorhabditis elegans] >gi|15375... 283 3e-74
emb|CAO16924.1| unnamed protein product [Vitis vinifera] 283 4e-74
ref|XP_001108979.1| PREDICTED: similar to acyl-Coenzyme A d... 282 4e-74
ref|XP_001217680.1| predicted protein [Aspergillus terreus ... 282 5e-74
ref|XP_001109036.1| PREDICTED: similar to acyl-Coenzyme A d... 282 5e-74
ref|NP_001064968.1| Os10g0498500 [Oryza sativa (japonica cu... 282 5e-74
ref|XP_512451.2| PREDICTED: abhydrolase domain containing 9... 282 6e-74
ref|XP_796464.1| PREDICTED: hypothetical protein [Strongylo... 282 6e-74
gb|EAW97971.1| acyl-Coenzyme A dehydrogenase family, member... 282 7e-74
gb|EAY79083.1| hypothetical protein OsI_033042 [Oryza sativ... 281 8e-74
gb|EAW97961.1| acyl-Coenzyme A dehydrogenase family, member... 281 1e-73
ref|NP_079070.1| abhydrolase domain containing 9 [Homo sapi... 281 1e-73
gb|EAW97967.1| acyl-Coenzyme A dehydrogenase family, member... 281 1e-73
gb|EAW97968.1| acyl-Coenzyme A dehydrogenase family, member... 280 1e-73
ref|XP_001109257.1| PREDICTED: similar to acyl-Coenzyme A d... 280 2e-73
ref|XP_001146527.1| PREDICTED: hypothetical protein isoform... 280 2e-73
ref|NP_001064966.1| Os10g0498200 [Oryza sativa (japonica cu... 280 3e-73
ref|XP_543398.2| PREDICTED: similar to acyl-Coenzyme A dehy... 280 3e-73
ref|ZP_02119758.1| hydrolase, alpha/beta fold family, putat... 280 3e-73
gb|EDL40330.1| mCG14254 [Mus musculus] 279 4e-73
ref|NP_927205.1| similar to epoxide hydrolase [Gloeobacter ... 279 4e-73
ref|NP_296269.1| epoxide hydrolase-related protein [Deinoco... 279 4e-73
ref|XP_001146998.1| PREDICTED: acyl-Coenzyme A dehydrogenas... 279 5e-73
ref|XP_509377.2| PREDICTED: acyl-Coenzyme A dehydrogenase f... 279 5e-73
ref|XP_001146445.1| PREDICTED: acyl-Coenzyme A dehydrogenas... 279 5e-73
ref|NP_001099464.1| abhydrolase domain containing 7 [Rattus... 279 5e-73
gb|AAI45798.1| Abhd9 protein [Mus musculus] 279 5e-73
ref|YP_001420483.1| YfhM [Bacillus amyloliquefaciens FZB42]... 279 6e-73
ref|YP_001641284.1| alpha/beta hydrolase fold [Methylobacte... 278 7e-73
ref|ZP_03999388.1| predicted hydrolase or acyltransferase o... 278 8e-73
ref|XP_001147201.1| PREDICTED: acyl-Coenzyme A dehydrogenas... 278 8e-73
ref|YP_001926939.1| alpha/beta hydrolase fold [Methylobacte... 278 8e-73
gb|EAW97963.1| acyl-Coenzyme A dehydrogenase family, member... 278 1e-72
ref|XP_001147058.1| PREDICTED: acyl-Coenzyme A dehydrogenas... 278 1e-72
gb|AAB02006.1| epoxide hydrolase [Nicotiana tabacum] 277 1e-72
gb|EAW97965.1| acyl-Coenzyme A dehydrogenase family, member... 277 1e-72
ref|XP_001491014.1| PREDICTED: similar to ACAD 10 [Equus ca... 277 2e-72
ref|NP_505662.1| K07C5.5 [Caenorhabditis elegans] >gi|38783... 277 2e-72
dbj|BAC03869.1| unnamed protein product [Homo sapiens] 277 2e-72
ref|ZP_01623368.1| epoxide hydrolase-like protein [Lyngbya ... 277 2e-72
ref|NP_001028335.1| abhydrolase domain containing 9 [Mus mu... 276 3e-72
gb|EAW97966.1| acyl-Coenzyme A dehydrogenase family, member... 276 3e-72
ref|XP_001585413.1| hypothetical protein SS1G_13652 [Sclero... 276 4e-72
gb|EDL19716.1| mCG142035, isoform CRA_a [Mus musculus] >gi|... 275 6e-72
ref|NP_079523.3| acyl-Coenzyme A dehydrogenase family, memb... 275 6e-72
ref|XP_001803986.1| hypothetical protein SNOG_13782 [Phaeos... 275 7e-72
ref|ZP_01039937.1| Alpha/beta hydrolase fold protein [Eryth... 275 9e-72
ref|XP_001367122.1| PREDICTED: hypothetical protein [Monode... 275 9e-72
ref|XP_001837532.1| hypothetical protein CC1G_01444 [Coprin... 275 1e-71
sp|Q3V1F8|ABHD9_MOUSE Abhydrolase domain-containing protein... 275 1e-71
ref|YP_761430.1| putative epoxide hydrolase [Hyphomonas nep... 274 1e-71
ref|XP_699161.2| PREDICTED: hypothetical protein [Danio rerio] 274 1e-71
gb|EAY79085.1| hypothetical protein OsI_033044 [Oryza sativ... 274 1e-71
ref|NP_001102458.1| abhydrolase domain containing 9 [Rattus... 274 2e-71
ref|ZP_01017814.1| Alpha/beta hydrolase fold protein [Parvu... 272 5e-71
ref|XP_001557163.1| epoxide hydrolase [Botryotinia fuckelia... 272 5e-71
emb|CAO23958.1| unnamed protein product [Vitis vinifera] 272 6e-71
ref|YP_483368.1| alpha/beta hydrolase fold [Frankia sp. CcI... 272 7e-71
ref|XP_001822366.1| hypothetical protein [Aspergillus oryza... 272 7e-71
ref|NP_082313.2| acyl-Coenzyme A dehydrogenase family, memb... 272 8e-71
ref|YP_716691.1| putative hydrolase [Frankia alni ACN14a] >... 271 1e-70
emb|CAO23957.1| unnamed protein product [Vitis vinifera] 270 2e-70
ref|YP_001771224.1| alpha/beta hydrolase fold [Methylobacte... 270 2e-70
ref|XP_875305.1| PREDICTED: hypothetical protein [Bos taurus] 270 2e-70
gb|EAZ29152.1| hypothetical protein OsJ_012635 [Oryza sativ... 270 2e-70
ref|ZP_01615341.1| Alpha/beta hydrolase fold protein [marin... 269 6e-70
ref|ZP_02016666.1| alpha/beta hydrolase fold [Halorubrum la... 269 6e-70
ref|XP_001824748.1| hypothetical protein [Aspergillus oryza... 269 6e-70
emb|CAN65368.1| hypothetical protein [Vitis vinifera] 268 8e-70
ref|YP_458350.1| possible epoxide hydrolase-related protein... 267 1e-69
ref|ZP_04000668.1| predicted hydrolase or acyltransferase o... 267 2e-69
ref|ZP_02118668.1| hydrolase, alpha/beta fold family, putat... 267 3e-69
emb|CAD31713.1| epoxide hydrolase [Cicer arietinum] 266 3e-69
ref|XP_001876554.1| epoxide hydrolase [Laccaria bicolor S23... 266 3e-69
Sequences not found previously or not previously below threshold:
>ref|XP_001163779.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 3 [Pan
troglodytes]
ref|XP_001163923.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 7 [Pan
troglodytes]
ref|XP_519676.2| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 8 [Pan
troglodytes]
Length = 555
Score = 919 bits (2375), Expect = 0.0, Method: Composition-based stats.
Identities = 549/555 (98%), Positives = 554/555 (99%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG+SS
Sbjct: 241 YVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGKSS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>ref|NP_001970.2| epoxide hydrolase 2, cytoplasmic [Homo sapiens]
sp|P34913|HYES_HUMAN Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
pdb|1S8O|A Chain A, Human Soluble Epoxide Hydrolase
pdb|1VJ5|A Chain A, Human Soluble Epoxide Hydrolase- N-Cyclohexyl-N'-(4-
Iodophenyl)urea Complex
pdb|1ZD2|P Chain P, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Ethanoic Acid Complex
pdb|1ZD3|A Chain A, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Butyric Acid Complex
pdb|1ZD4|A Chain A, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Hexanoic Acid Complex
pdb|1ZD5|A Chain A, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Heptanoic Acid Complex
gb|AAG14966.1|AF233334_1 soluble epoxide hydrolase [Homo sapiens]
emb|CAA65751.1| epoxide hydrolase [Homo sapiens]
gb|AAH07708.1| Epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAH11628.1| Epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAH13874.1| Epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAP35531.1| epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAX42304.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
gb|AAX42305.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
gb|EAW63548.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_b [Homo sapiens]
gb|ABM83675.1| epoxide hydrolase 2, cytoplasmic [synthetic construct]
gb|ABM86963.1| epoxide hydrolase 2, cytoplasmic [synthetic construct]
gb|ACD11487.1| epoxide hydrolase 2, cytoplasmic [Homo sapiens]
Length = 555
Score = 918 bits (2374), Expect = 0.0, Method: Composition-based stats.
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>gb|AAP36260.1| Homo sapiens epoxide hydrolase 2, cytoplasmic [synthetic construct]
gb|AAX29746.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
gb|AAX29747.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
Length = 556
Score = 918 bits (2374), Expect = 0.0, Method: Composition-based stats.
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>gb|AAG14967.1|AF233335_1 soluble epoxide hydrolase [Homo sapiens]
Length = 555
Score = 916 bits (2367), Expect = 0.0, Method: Composition-based stats.
Identities = 554/555 (99%), Positives = 555/555 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGY+VLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYQVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>gb|AAG14968.1|AF233336_1 soluble epoxide hydrolase [Homo sapiens]
Length = 556
Score = 914 bits (2362), Expect = 0.0, Method: Composition-based stats.
Identities = 554/556 (99%), Positives = 554/556 (99%), Gaps = 1/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNL-SRTFKSLFRASDESVLSM 419
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNL RTFKSLFRASDESVLSM
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRRTFKSLFRASDESVLSM 420
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS
Sbjct: 421 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 480
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI
Sbjct: 481 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 540
Query: 540 KWLDSDARNPPVVSKM 555
KWLDSDARNPPVVSKM
Sbjct: 541 KWLDSDARNPPVVSKM 556
>gb|EAW63547.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Homo sapiens]
Length = 568
Score = 911 bits (2354), Expect = 0.0, Method: Composition-based stats.
Identities = 554/568 (97%), Positives = 554/568 (97%), Gaps = 13/568 (2%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPR-------------GLLNDAFQKGGPE 47
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALP GLLNDAFQKGGPE
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPSSGGWKSKIKMSAGGLLNDAFQKGGPE 60
Query: 48 GATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQ 107
GATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQ
Sbjct: 61 GATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQ 120
Query: 108 AALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYK 167
AALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYK
Sbjct: 121 AALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYK 180
Query: 168 FLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAP 227
FLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAP
Sbjct: 181 FLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAP 240
Query: 228 LPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYR 287
LPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYR
Sbjct: 241 LPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYR 300
Query: 288 VLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALF 347
VLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALF
Sbjct: 301 VLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALF 360
Query: 348 YPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS 407
YPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS
Sbjct: 361 YPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS 420
Query: 408 LFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYR 467
LFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYR
Sbjct: 421 LFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYR 480
Query: 468 NMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ 527
NMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ
Sbjct: 481 NMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ 540
Query: 528 MDKPTEVNQILIKWLDSDARNPPVVSKM 555
MDKPTEVNQILIKWLDSDARNPPVVSKM
Sbjct: 541 MDKPTEVNQILIKWLDSDARNPPVVSKM 568
>ref|XP_001163896.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 6 [Pan
troglodytes]
Length = 560
Score = 905 bits (2340), Expect = 0.0, Method: Composition-based stats.
Identities = 544/560 (97%), Positives = 551/560 (98%), Gaps = 5/560 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQ-----AGYRVLAMDMKG 295
YVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQ+ L + AGYRVLAMDMKG
Sbjct: 241 YVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQVRKLGKMQPVRAGYRVLAMDMKG 300
Query: 296 YGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV 355
YG+SSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV
Sbjct: 301 YGKSSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV 360
Query: 356 ASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES 415
ASLNTPFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES
Sbjct: 361 ASLNTPFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES 420
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW
Sbjct: 421 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 480
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 535
ACKSLGRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVN
Sbjct: 481 ACKSLGRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 540
Query: 536 QILIKWLDSDARNPPVVSKM 555
QILIKWLDSDARNPPVVSKM
Sbjct: 541 QILIKWLDSDARNPPVVSKM 560
>gb|AAA02756.1| cytosolic epoxide hydrolase
Length = 554
Score = 905 bits (2340), Expect = 0.0, Method: Composition-based stats.
Identities = 552/555 (99%), Positives = 552/555 (99%), Gaps = 1/555 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLR AVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRGAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELG PAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELG-WPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 299
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 300 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 359
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 360 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 419
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 420 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 479
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 480 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 539
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 540 WLDSDARNPPVVSKM 554
>ref|XP_001109474.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic [Macaca
mulatta]
Length = 556
Score = 888 bits (2296), Expect = 0.0, Method: Composition-based stats.
Identities = 519/556 (93%), Positives = 538/556 (96%), Gaps = 1/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAF KGGPEGATTRLM+GEITL
Sbjct: 1 MALRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFHKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCS+T++V LPKNFS+ EIF KAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSQTSEVSLPKNFSVNEIFGKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELK HFDFLIESCQVGMVKPEPQIY+FLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKTHFDFLIESCQVGMVKPEPQIYRFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD+G+NLKPARDLGMVTILVQDTDTAL+ELEKVTGIQLLNTPAPLPT CNPSD+SHG
Sbjct: 181 VFLDDVGSNLKPARDLGMVTILVQDTDTALRELEKVTGIQLLNTPAPLPTCCNPSDVSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVT+KP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRV+AMDMKGYGESS
Sbjct: 241 YVTIKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVIAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMV-TFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
APPEIEEYCMEVLCKE V +LGLSQAVFIGHDWGG+LVWYMALFYPERVRAVASLN
Sbjct: 301 APPEIEEYCMEVLCKETVPRLAGELGLSQAVFIGHDWGGVLVWYMALFYPERVRAVASLN 360
Query: 360 TPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSM 419
TPFIPANPN+ PLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSM
Sbjct: 361 TPFIPANPNVPPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSM 420
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HKVCE GGLFV +PEEPSLSRMV+EEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS
Sbjct: 421 HKVCEMGGLFVRTPEEPSLSRMVSEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 480
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKP EVNQILI
Sbjct: 481 LGRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPAEVNQILI 540
Query: 540 KWLDSDARNPPVVSKM 555
KWL+SDARNPPVVSKM
Sbjct: 541 KWLESDARNPPVVSKM 556
>ref|NP_001069002.1| epoxide hydrolase 2, cytoplasmic [Bos taurus]
gb|AAI18307.1| Epoxide hydrolase 2, cytoplasmic [Bos taurus]
Length = 555
Score = 849 bits (2193), Expect = 0.0, Method: Composition-based stats.
Identities = 415/555 (74%), Positives = 488/555 (87%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVF+L G+L LP+ R EE LALP G L+ AF +GGP+G + R+MKGEIT
Sbjct: 1 MALRAAVFELGGILTLPSATSFWDRAEEELALPGGFLSKAFLRGGPDGPSIRVMKGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+P MEE+CRKCS+ +CLP+NFSIK+IF+K +S+RKIN PMLQAA+ L++KGFTT
Sbjct: 61 SQWVPFMEEDCRKCSKDCGICLPENFSIKQIFEKILSSRKINYPMLQAAVTLKQKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDD AER LAQ++CELK HFDFLIESCQ+GMVKP+PQIYKF+LDTLK SPSEV
Sbjct: 121 ILTNTWLDDSAERGSLAQVLCELKPHFDFLIESCQIGMVKPDPQIYKFVLDTLKISPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLD+ NLKPA ++GMVTI V DTD ALKELEKVTG+QLL T AP P SC+PS M+HG
Sbjct: 181 VFLDNFETNLKPAHEMGMVTIFVHDTDAALKELEKVTGVQLLQTSAPQPISCDPSTMTHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLHFVELGSGP VCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHFVELGSGPVVCLCHGFPESWFSWRYQIPALAQAGFRVLAVDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY +EVL K+M+TFLDKLG+SQAVFIGHDWGGMLVW +ALF+PERVRAVASLNT
Sbjct: 301 APPEIEEYSLEVLSKDMITFLDKLGISQAVFIGHDWGGMLVWTIALFHPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+P+NP +S +E IKA P F+YQLYFQEPGVAEAELE+NLSRTFKS FR++DE+ +++
Sbjct: 361 PFMPSNPKVSTMEIIKATPTFNYQLYFQEPGVAEAELEKNLSRTFKSFFRSNDETFITVS 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+ CE GGL VN+PEEP+LS+MVTEE+IQFYVQ+FKKSGFRGPLNWYRNM++NW+W K
Sbjct: 421 RTCEMGGLLVNTPEEPTLSKMVTEEDIQFYVQEFKKSGFRGPLNWYRNMDKNWEWGFKGS 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKD VL P+MS+HMEDWIPHLKRGHI+DCGHWTQM+KPTE+N+ILI+
Sbjct: 481 GRKILIPALMVTAEKDLVLTPEMSKHMEDWIPHLKRGHIKDCGHWTQMEKPTELNRILIE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DAR+ PVVSK+
Sbjct: 541 WLETDARDLPVVSKL 555
>ref|XP_001163527.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 1 [Pan
troglodytes]
Length = 502
Score = 845 bits (2183), Expect = 0.0, Method: Composition-based stats.
Identities = 496/502 (98%), Positives = 501/502 (99%)
Query: 54 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 113
M+GEITLSQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLR
Sbjct: 1 MRGEITLSQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLR 60
Query: 114 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 173
KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL
Sbjct: 61 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 120
Query: 174 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 233
KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN
Sbjct: 121 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 180
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
PSDMSHGYVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM
Sbjct: 181 PSDMSHGYVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 240
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
KGYG+SSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR
Sbjct: 241 KGYGKSSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 300
Query: 354 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 413
AVASLNTPFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD
Sbjct: 301 AVASLNTPFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 360
Query: 414 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 473
ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW
Sbjct: 361 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 420
Query: 474 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 533
KWACKSLGRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTE
Sbjct: 421 KWACKSLGRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTE 480
Query: 534 VNQILIKWLDSDARNPPVVSKM 555
VNQILIKWLDSDARNPPVVSKM
Sbjct: 481 VNQILIKWLDSDARNPPVVSKM 502
>gb|EAW63549.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_c [Homo sapiens]
Length = 502
Score = 844 bits (2182), Expect = 0.0, Method: Composition-based stats.
Identities = 502/502 (100%), Positives = 502/502 (100%)
Query: 54 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 113
MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR
Sbjct: 1 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 60
Query: 114 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 173
KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL
Sbjct: 61 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 120
Query: 174 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 233
KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN
Sbjct: 121 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 180
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM
Sbjct: 181 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 240
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR
Sbjct: 241 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 300
Query: 354 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 413
AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD
Sbjct: 301 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 360
Query: 414 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 473
ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW
Sbjct: 361 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 420
Query: 474 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 533
KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE
Sbjct: 421 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 480
Query: 534 VNQILIKWLDSDARNPPVVSKM 555
VNQILIKWLDSDARNPPVVSKM
Sbjct: 481 VNQILIKWLDSDARNPPVVSKM 502
>ref|NP_001001641.1| soluble epoxide hydrolase [Sus scrofa]
sp|Q6Q2C2|HYES_PIG Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
gb|AAS68016.1| soluble epoxide hydrolase [Sus scrofa]
Length = 555
Score = 841 bits (2173), Expect = 0.0, Method: Composition-based stats.
Identities = 430/555 (77%), Positives = 494/555 (89%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP++ R EE LALPRG LN+AF+KGG +G+ R+M GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSITTSWARAEEKLALPRGFLNEAFKKGGQDGSVARVMTGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+P MEE+CRKC+E + + LP+NFS+K IFDKA+S +KIN PMLQAAL L+KKGF+T
Sbjct: 61 SQWVPFMEEDCRKCAEDSGIRLPENFSVKHIFDKALSEKKINYPMLQAALTLKKKGFSTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD A+R AQLMCEL+ HFDFLIESC+VGM KP+PQIYK +LDTLKA P+EV
Sbjct: 121 ILTNNWLDDSAQRGSRAQLMCELRPHFDFLIESCRVGMAKPDPQIYKLMLDTLKAEPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD+G +LKP RDLGM TILV+DTDTAL+ELEKVTG+QLL TPA PTSC+PS +SHG
Sbjct: 181 VFLDDVGTHLKPVRDLGMATILVRDTDTALRELEKVTGVQLLQTPALPPTSCDPSALSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLHFVE+GSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVLIKPGVRLHFVEMGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLAVDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY +EVLCK+MVTFL+KLGLSQAVFIGHDWGG+LVW MALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYSLEVLCKDMVTFLNKLGLSQAVFIGHDWGGVLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+P+NPN+SP+E IKANPVFDYQLYFQEPGVAEAELEQNL RTFK+ FRA DE+ L+ +
Sbjct: 361 PFMPSNPNVSPMEIIKANPVFDYQLYFQEPGVAEAELEQNLDRTFKNFFRAHDETFLTTN 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+V E GGLFV +PEEPSLSR+VTEE+IQFYVQQFKKSGFRGPLNWYRNMERNW+W CK
Sbjct: 421 RVRELGGLFVGTPEEPSLSRLVTEEDIQFYVQQFKKSGFRGPLNWYRNMERNWQWGCKGS 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAE D VL P+MS+HME+WIPHLKRGHI+DCGHWTQ+DKP E+N+ILI+
Sbjct: 481 GRKILIPALMVTAENDLVLHPKMSKHMENWIPHLKRGHIKDCGHWTQIDKPAELNRILIE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DARNP V SK+
Sbjct: 541 WLETDARNPLVDSKL 555
>ref|XP_534566.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 1
[Canis familiaris]
Length = 556
Score = 838 bits (2165), Expect = 0.0, Method: Composition-based stats.
Identities = 436/556 (78%), Positives = 497/556 (89%), Gaps = 1/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+QLL T A LP CNPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQLLQTAAALPVPCNPSDMSHV 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 301 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD-ESVLSM 419
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD + L++
Sbjct: 361 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKPFLNV 420
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+V E GGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W CK
Sbjct: 421 GRVRERGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGCKG 480
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
+GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQILI
Sbjct: 481 VGRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQILI 540
Query: 540 KWLDSDARNPPVVSKM 555
+WL++DAR+PPVVSK+
Sbjct: 541 EWLETDARDPPVVSKL 556
>ref|XP_857471.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 3
[Canis familiaris]
Length = 555
Score = 837 bits (2162), Expect = 0.0, Method: Composition-based stats.
Identities = 435/555 (78%), Positives = 493/555 (88%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+QLL T A LP CNPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQLLQTAAALPVPCNPSDMSHV 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 301 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD V
Sbjct: 361 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKVSVAE 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+ AGGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W CK +
Sbjct: 421 RWLFAGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGCKGV 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQILI+
Sbjct: 481 GRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQILIE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DAR+PPVVSK+
Sbjct: 541 WLETDARDPPVVSKL 555
>ref|XP_001492725.1| PREDICTED: similar to soluble epoxide hydrolase [Equus caballus]
Length = 555
Score = 836 bits (2161), Expect = 0.0, Method: Composition-based stats.
Identities = 437/555 (78%), Positives = 495/555 (89%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP++ GR EE LALPRG L++A GP+ + RL+ GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSIARAFGRAEEDLALPRGFLSEALNLKGPDESIARLVTGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+P ++E+C+K S+ + + LP+ FSI +IF KAISARKIN PMLQAAL LRKKGFTT
Sbjct: 61 SQWVPFIDEDCKKRSKNSGINLPEEFSINQIFAKAISARKINHPMLQAALTLRKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD +ER LAQL+CEL+ HFDFLIESC++ M KPEPQIYK++LDTLKASP+EV
Sbjct: 121 ILTNNWLDDSSERGTLAQLLCELRPHFDFLIESCRIRMAKPEPQIYKYVLDTLKASPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGA LKPARDLGMVTILV+DTDTAL+ELEKVTG+QLL T APLPT C+P+D+SHG
Sbjct: 181 VFLDDIGAYLKPARDLGMVTILVRDTDTALRELEKVTGMQLLKTAAPLPTPCSPNDVSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLHFVELG GPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHFVELGCGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLAVDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY MEVLCK+MVTFLDKLG+SQAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYSMEVLCKDMVTFLDKLGISQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+PANPN+SP+E IKANPVF+YQLYFQEPGVAEAELEQNLSRTFKS FR SDE LS
Sbjct: 361 PFMPANPNVSPMEIIKANPVFNYQLYFQEPGVAEAELEQNLSRTFKSFFRTSDEGFLSTS 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+VCE GGLFV +PEEPSLS MV+EE+IQFYVQQF+KSGFRGPLNWYRN+ERNW+W CK
Sbjct: 421 RVCERGGLFVAAPEEPSLSSMVSEEDIQFYVQQFRKSGFRGPLNWYRNVERNWQWGCKGS 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKD VLVP+MS+HMEDWIPHLKRGHI+DCGHWTQM+KPTE+NQIL +
Sbjct: 481 GRKILIPALMVTAEKDVVLVPEMSKHMEDWIPHLKRGHIKDCGHWTQMEKPTELNQILTE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DAR+P VVSK+
Sbjct: 541 WLETDARDPLVVSKL 555
>ref|XP_001163861.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 5 [Pan
troglodytes]
Length = 523
Score = 834 bits (2155), Expect = 0.0, Method: Composition-based stats.
Identities = 518/555 (93%), Positives = 523/555 (94%), Gaps = 32/555 (5%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVK IPALAQAGYRVLAMDMKGYG+SS
Sbjct: 241 YVTVK--------------------------------IPALAQAGYRVLAMDMKGYGKSS 268
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 269 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 328
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 329 PFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 388
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 389 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 448
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 449 GRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 508
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 509 WLDSDARNPPVVSKM 523
>ref|XP_857554.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 4
[Canis familiaris]
Length = 554
Score = 832 bits (2151), Expect = 0.0, Method: Composition-based stats.
Identities = 432/556 (77%), Positives = 495/556 (89%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+Q + P+P CNPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQSPKSALPVP--CNPSDMSHV 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 239 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD-ESVLSM 419
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD + L++
Sbjct: 359 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKPFLNV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+V E GGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W CK
Sbjct: 419 GRVRERGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
+GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQILI
Sbjct: 479 VGRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
+WL++DAR+PPVVSK+
Sbjct: 539 EWLETDARDPPVVSKL 554
>ref|XP_857430.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 2
[Canis familiaris]
Length = 556
Score = 830 bits (2144), Expect = 0.0, Method: Composition-based stats.
Identities = 429/558 (76%), Positives = 489/558 (87%), Gaps = 5/558 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+Q + P+P CNPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQSPKSALPVP--CNPSDMSHV 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 239 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVL--- 417
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD
Sbjct: 359 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKGFETC 418
Query: 418 SMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWAC 477
+ GGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W C
Sbjct: 419 ANRPATAVGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGC 478
Query: 478 KSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQI 537
K +GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQI
Sbjct: 479 KGVGRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQI 538
Query: 538 LIKWLDSDARNPPVVSKM 555
LI+WL++DAR+PPVVSK+
Sbjct: 539 LIEWLETDARDPPVVSKL 556
>ref|XP_001163819.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 4 [Pan
troglodytes]
Length = 514
Score = 826 bits (2133), Expect = 0.0, Method: Composition-based stats.
Identities = 508/555 (91%), Positives = 513/555 (92%), Gaps = 41/555 (7%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE- 179
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
LLNTPAPLPTSCNPSDMSHG
Sbjct: 180 ----------------------------------------LLNTPAPLPTSCNPSDMSHG 199
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG+SS
Sbjct: 200 YVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGKSS 259
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 260 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 319
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 320 PFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 379
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 380 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 439
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 440 GRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 499
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 500 WLDSDARNPPVVSKM 514
>gb|EAW63551.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_e [Homo sapiens]
Length = 489
Score = 822 bits (2123), Expect = 0.0, Method: Composition-based stats.
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 67 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 126
MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW
Sbjct: 1 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 60
Query: 127 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 186
LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI
Sbjct: 61 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 120
Query: 187 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 246
GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP
Sbjct: 121 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 180
Query: 247 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 306
RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE
Sbjct: 181 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 240
Query: 307 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 366
EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN
Sbjct: 241 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 300
Query: 367 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 426
PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG
Sbjct: 301 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 360
Query: 427 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 486
GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI
Sbjct: 361 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 420
Query: 487 PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 546
PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA
Sbjct: 421 PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 480
Query: 547 RNPPVVSKM 555
RNPPVVSKM
Sbjct: 481 RNPPVVSKM 489
>ref|XP_001163565.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 2 [Pan
troglodytes]
Length = 489
Score = 821 bits (2122), Expect = 0.0, Method: Composition-based stats.
Identities = 484/489 (98%), Positives = 488/489 (99%)
Query: 67 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 126
MEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW
Sbjct: 1 MEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 60
Query: 127 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 186
LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI
Sbjct: 61 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 120
Query: 187 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 246
GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP
Sbjct: 121 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 180
Query: 247 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 306
VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG+SSAPPEIE
Sbjct: 181 GVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGKSSAPPEIE 240
Query: 307 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 366
EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN
Sbjct: 241 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 300
Query: 367 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 426
PN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG
Sbjct: 301 PNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 360
Query: 427 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 486
GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI
Sbjct: 361 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 420
Query: 487 PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 546
PALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA
Sbjct: 421 PALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 480
Query: 547 RNPPVVSKM 555
RNPPVVSKM
Sbjct: 481 RNPPVVSKM 489
>ref|NP_075225.1| epoxide hydrolase 2, cytoplasmic [Rattus norvegicus]
sp|P80299|HYES_RAT Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
emb|CAA46211.1| epoxide hydrolase [Rattus norvegicus]
Length = 554
Score = 815 bits (2106), Expect = 0.0, Method: Composition-based stats.
Identities = 404/556 (72%), Positives = 481/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ GVL TEEALALPR L AFQ PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+CRK S+ LP+NFSI EIF +A++AR INRPMLQAA L+KKGFTT
Sbjct: 61 SQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIYKF+LDTLKA P+EV
Sbjct: 121 IVTNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV+DT +AL+ELEKVTG Q P P+P C+P+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFPEAPLPVP--CSPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LC+EMVTFL+KLG+ QAVFIGHDW G+LVW MALF+PERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMALFHPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
P +P NP +SP+E I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FR SD+ +L++
Sbjct: 359 PLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+K E GG+ V +PE+P +S++ TEEEI++Y+QQFKKSGFRGPLNWYRN ERNWKW+CK+
Sbjct: 419 NKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLNWYRNTERNWKWSCKA 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME+WIP LKRGHIEDCGHWTQ++KP EVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGHWTQIEKPAEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLKTEIQNPSVTSKI 554
>gb|AAH85732.1| Epoxide hydrolase 2, cytoplasmic [Rattus norvegicus]
gb|EDL85376.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Rattus norvegicus]
Length = 554
Score = 814 bits (2103), Expect = 0.0, Method: Composition-based stats.
Identities = 403/556 (72%), Positives = 479/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ GVL TEEALALPR L AFQ PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+CRK S+ LP+NFSI EIF +A++AR INRPMLQAA L+KKGFTT
Sbjct: 61 SQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIYKF+LDTLKA P+EV
Sbjct: 121 IITNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV+DT +AL+ELEKVTG Q P P+P C+P+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFPEAPLPVP--CSPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP + LHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGICLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LC+EMVTFL+KLG+ QAVFIGHDW G+LVW MALF+PERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMALFHPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
P +P NP +SP+E I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FR SD+ +L++
Sbjct: 359 PLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+K E GG+ V +PE+P +S++ TEEEI++Y+QQFKKSGFRGPLNWYRN ERNWKW CK+
Sbjct: 419 NKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLNWYRNTERNWKWNCKA 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME+WIP LKRGHIEDCGHWTQ++KP EVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGHWTQIEKPAEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLKTEIQNPSVTSKI 554
>emb|CAA85471.1| Epoxide Hydrolase [Mus musculus]
Length = 554
Score = 813 bits (2101), Expect = 0.0, Method: Composition-based stats.
Identities = 406/556 (73%), Positives = 482/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ G R+EEALALPR L A+Q PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+ RK S+T LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT
Sbjct: 61 SQWVPLMDESYRKSSKTCGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P+EV
Sbjct: 121 IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P CNP+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVP--CNPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
PF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE +++
Sbjct: 359 PFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK
Sbjct: 419 HKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLQTEVQNPSVTSKI 554
>ref|NP_031966.2| epoxide hydrolase 2, cytoplasmic [Mus musculus]
sp|P34914|HYES_MOUSE Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
pdb|1CQZ|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase.
pdb|1CQZ|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase.
pdb|1CR6|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cpu Inhibitor
pdb|1CR6|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cpu Inhibitor
pdb|1EK1|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Ciu Inhibitor
pdb|1EK1|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Ciu Inhibitor
pdb|1EK2|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cdu Inhibitor
pdb|1EK2|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cdu Inhibitor
gb|AAA37555.1| epoxide hydrolase
gb|AAH15087.1| Epoxide hydrolase 2, cytoplasmic [Mus musculus]
gb|EDL36005.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Mus musculus]
Length = 554
Score = 812 bits (2098), Expect = 0.0, Method: Composition-based stats.
Identities = 405/556 (72%), Positives = 481/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ G R+EEALALPR L A+Q PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT
Sbjct: 61 SQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P+EV
Sbjct: 121 IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P CNP+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVP--CNPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
PF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE +++
Sbjct: 359 PFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK
Sbjct: 419 HKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLQTEVQNPSVTSKI 554
>dbj|BAE25172.1| unnamed protein product [Mus musculus]
Length = 554
Score = 812 bits (2097), Expect = 0.0, Method: Composition-based stats.
Identities = 404/556 (72%), Positives = 481/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ G R+EEALALPR L A+Q PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT
Sbjct: 61 SQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEP+IY FLLDTLKA P+EV
Sbjct: 121 IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPRIYNFLLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P CNP+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVP--CNPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
PF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE +++
Sbjct: 359 PFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK
Sbjct: 419 HKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLQTEVQNPSVTSKI 554
>gb|EDL85377.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_b [Rattus norvegicus]
Length = 512
Score = 761 bits (1966), Expect = 0.0, Method: Composition-based stats.
Identities = 373/513 (72%), Positives = 447/513 (87%), Gaps = 3/513 (0%)
Query: 44 GGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINR 103
PEG T +LMKG+IT SQW+PLM+E+CRK S+ LP+NFSI EIF +A++AR INR
Sbjct: 2 KFPEGPTEQLMKGKITFSQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINR 61
Query: 104 PMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEP 163
PMLQAA L+KKGFTT I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEP
Sbjct: 62 PMLQAAAALKKKGFTTCIITNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEP 121
Query: 164 QIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLN 223
QIYKF+LDTLKA P+EVVFLDD G+NLKPARD+GMVTILV+DT +AL+ELEKVTG Q
Sbjct: 122 QIYKFVLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFPE 181
Query: 224 TPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQ 283
P P+P C+P+D+SHGYVTVKP + LHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQ
Sbjct: 182 APLPVP--CSPNDVSHGYVTVKPGICLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQ 239
Query: 284 AGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWY 343
AG+RVLA+DMKGYG+SS+PPEIEEY ME+LC+EMVTFL+KLG+ QAVFIGHDW G+LVW
Sbjct: 240 AGFRVLAIDMKGYGDSSSPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWN 299
Query: 344 MALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSR 403
MALF+PERVRAVASLNTP +P NP +SP+E I++ PVF+YQLYFQEPGVAEAELE+N+SR
Sbjct: 300 MALFHPERVRAVASLNTPLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSR 359
Query: 404 TFKSLFRASDE-SVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGP 462
TFKS FR SD+ +L+++K E GG+ V +PE+P +S++ TEEEI++Y+QQFKKSGFRGP
Sbjct: 360 TFKSFFRTSDDMGLLTVNKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGP 419
Query: 463 LNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDC 522
LNWYRN ERNWKW CK+LGRKIL+PALMVTAEKD VL P+MS++ME+WIP LKRGHIEDC
Sbjct: 420 LNWYRNTERNWKWNCKALGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDC 479
Query: 523 GHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM 555
GHWTQ++KP EVNQILIKWL ++ +NP V SK+
Sbjct: 480 GHWTQIEKPAEVNQILIKWLKTEIQNPSVTSKI 512
>ref|XP_001380051.1| PREDICTED: similar to soluble epoxide hydrolase [Monodelphis
domestica]
Length = 562
Score = 753 bits (1945), Expect = 0.0, Method: Composition-based stats.
Identities = 345/562 (61%), Positives = 431/562 (76%), Gaps = 7/562 (1%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAA+FDL GVL P++ + + EEALALPRG LN +GG E L+KGEIT
Sbjct: 1 MGLRAALFDLGGVLVHPSMNIIFSQAEEALALPRGFLNKVITQGGLESPYVHLIKGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE+CRK S + CLP+ FS+++IF+ IS KIN PML+AA+ LR KG+ T
Sbjct: 61 SQWVPLMEEDCRKLSVASNFCLPEQFSLQKIFEDMISEGKINYPMLRAAITLRNKGYKTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD +R+ +AQLMC L HFD +IESC++GMVKP+P+IYKF L+ LK +P E
Sbjct: 121 ILTNNWLDDGLQRNVIAQLMCTLSKHFDLVIESCRIGMVKPDPEIYKFALEALKVAPHEA 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD GANLK AR+LGMVTIL QDTD ALKELEK TG+Q N P + +PS+++HG
Sbjct: 181 VFLDDTGANLKKARELGMVTILAQDTDMALKELEKSTGVQFPNHDMERPIAVHPSNIAHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV VKP V+LHFVE GSGP VCL HGFPE WYSW+ QIP L +AG+RV+A+D+KG+G+SS
Sbjct: 241 YVEVKPGVQLHFVEKGSGPVVCLFHGFPEFWYSWKCQIPVLVEAGFRVIALDLKGFGDSS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
AP EIEEY EV+CKE++TFLDKL +SQA+ IGHDWGG+LVW MA+FYPERVRAVAS+N+
Sbjct: 301 APYEIEEYSQEVICKELITFLDKLDISQAICIGHDWGGLLVWNMAIFYPERVRAVASVNS 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF P +P + E +K NPVF+YQ YFQ+PGVAEAELEQ+L+RTFK LFRASDE + M
Sbjct: 361 PFFPPDPVVPLKEKLKKNPVFNYQFYFQKPGVAEAELEQDLTRTFKILFRASDERKVCML 420
Query: 421 KVC---EAGGLF----VNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 473
GLF + E P LS M+TEE+I +YVQQ+KKSGFRGPLNWYRN + NW
Sbjct: 421 HTGTIVGNRGLFFIGILKKIENPFLSWMLTEEDINYYVQQYKKSGFRGPLNWYRNHDANW 480
Query: 474 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 533
+W+C + RKIL+PALMV AE D VL P++S++ME WIPHLKR +I++CGHWTQ+++P E
Sbjct: 481 RWSCMATKRKILVPALMVIAENDVVLSPKLSENMEKWIPHLKRAYIKNCGHWTQLERPRE 540
Query: 534 VNQILIKWLDSDARNPPVVSKM 555
+NQILI+WL + P +VS +
Sbjct: 541 LNQILIEWLKDVTKTPSMVSLL 562
>ref|NP_001087143.1| epoxide hydrolase 2, cytoplasmic [Xenopus laevis]
gb|AAH78066.1| Ephx2-prov protein [Xenopus laevis]
Length = 560
Score = 753 bits (1944), Expect = 0.0, Method: Composition-based stats.
Identities = 313/558 (56%), Positives = 406/558 (72%), Gaps = 6/558 (1%)
Query: 3 LRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQ 62
R +FDL GVL P R E +L LP G L + F + G EG +G+I S+
Sbjct: 4 KRFVLFDLGGVLLTPGPQSAFQRLETSLHLPSGFLQNVFTRSGSEGPFAMAERGKIPFSK 63
Query: 63 WIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAIL 122
++ M + CR +E + V LP++FS+++ F IN+PML+AA+ LR GF T +L
Sbjct: 64 FVAEMNKECRAFAEESGVSLPESFSLEQAFHGMFENGGINKPMLKAAVKLRHHGFKTCVL 123
Query: 123 TNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVF 182
TN W+DD +R A+++ L HFD ++ESC++GM KPE QIY++ L L A P E +F
Sbjct: 124 TNNWIDDSPQRSLSAEVLSSLSRHFDLVVESCRIGMRKPETQIYEYALKLLHAKPKETIF 183
Query: 183 LDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYV 242
LDDIGANLKPAR++G+ T+LV+DT+TALKEL+ ++ + L+ P NP ++HG+V
Sbjct: 184 LDDIGANLKPAREMGIATVLVKDTETALKELQALSNVPLIENEEVAPIPANPDKVTHGFV 243
Query: 243 TVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAP 302
TVKP V+LH+VE+G+GP +CLCHGFPESWYSWR+QIPALA AG+RV+A DMKGYG+SSAP
Sbjct: 244 TVKPGVKLHYVEMGNGPVICLCHGFPESWYSWRFQIPALADAGFRVIAFDMKGYGDSSAP 303
Query: 303 PEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPF 362
EIEEY E +CK++V+FLD LG+SQA FIGHDWGG +VW MALFYPERVRAVASLNTPF
Sbjct: 304 HEIEEYSQEQICKDLVSFLDALGISQASFIGHDWGGAVVWNMALFYPERVRAVASLNTPF 363
Query: 363 IPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-----SVL 417
+ P ++ LE IKANP+FDYQLYFQEPGVAEAELE+NL RTFK FR S E + L
Sbjct: 364 FTSEPGVNALERIKANPIFDYQLYFQEPGVAEAELEKNLERTFKVFFRGSSEKDRLPTTL 423
Query: 418 SMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWAC 477
+ V E GG+ V + E+ LS ++ E ++ +YV QFKKSGFRGPLNWYRNM+RN +W+
Sbjct: 424 TTMNVRERGGILVGTDEDTPLSSIINEADLHYYVAQFKKSGFRGPLNWYRNMQRNSEWSI 483
Query: 478 KSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQI 537
+ G KIL+PALMVTA KDFVL+P M++ ME+ IP+L RGHIE+C HWTQM++P VN+I
Sbjct: 484 SAHGWKILVPALMVTAGKDFVLLPIMTKGMENLIPNLSRGHIEECSHWTQMERPAAVNEI 543
Query: 538 LIKWLDSDARNPPVVSKM 555
LIKWL + N PV SK+
Sbjct: 544 LIKWL-GEVLNLPVTSKL 560
>ref|NP_001006912.1| epoxide hydrolase 2, cytoplasmic [Xenopus tropicalis]
gb|AAH75370.1| Epoxide hydrolase 2, cytoplasmic [Xenopus tropicalis]
Length = 560
Score = 752 bits (1942), Expect = 0.0, Method: Composition-based stats.
Identities = 317/559 (56%), Positives = 410/559 (73%), Gaps = 6/559 (1%)
Query: 2 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLS 61
R +FDL GVL P R E +L+LP G L + F + G EG R +G+I S
Sbjct: 3 ARRFVLFDLGGVLLTPGPQVAFQRLERSLSLPSGFLQNVFVRSGSEGPFARAERGQIPFS 62
Query: 62 QWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAI 121
++I M++ C+ +E + V LP +FS+++ F + IN+PML+AA+ LR GF T +
Sbjct: 63 KFIAEMDKECKAFAEESGVSLPDSFSLEQTFHGMFESGGINKPMLKAAVTLRHHGFKTCV 122
Query: 122 LTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVV 181
LTN W+DD +R A+L L HFD ++ESC+ GM KPE QIY + L LKA+P E +
Sbjct: 123 LTNNWIDDSPQRSHSAELFSSLNRHFDLVVESCRTGMRKPETQIYDYALKMLKANPKETI 182
Query: 182 FLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGY 241
FLDDIGANLKPAR++G+ T+LV+DT+TALKEL+ ++G+ L P NP +++HG
Sbjct: 183 FLDDIGANLKPAREMGIATVLVKDTETALKELQALSGVPLFENEEVTPVPANPDNVTHGS 242
Query: 242 VTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSA 301
VTVKP V+LH+VE+G+GP +CLCHGFPESWYSWR+QIPALA AG+RV+A DMKGYG+SSA
Sbjct: 243 VTVKPGVQLHYVEMGNGPVICLCHGFPESWYSWRFQIPALADAGFRVIAFDMKGYGDSSA 302
Query: 302 PPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTP 361
P EIEEY E +CK++V+FLD +G+SQA FIGHDWGG +VW MALFYPERVRAVASLNTP
Sbjct: 303 PQEIEEYSQEQICKDLVSFLDVMGISQASFIGHDWGGAVVWNMALFYPERVRAVASLNTP 362
Query: 362 FIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-----SV 416
F ++P ++ LE IKANP+FDYQLYFQEPGVAEAELE++L RTFK FR S E +
Sbjct: 363 FFTSDPGVNALERIKANPIFDYQLYFQEPGVAEAELEKDLERTFKVFFRGSSEKDRLATS 422
Query: 417 LSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWA 476
L+ V E GG+ V + E+P LS ++ E ++Q+YV QFKKSGFRGPLNWYRNM+RN +W
Sbjct: 423 LTTMNVRERGGILVGTDEDPPLSSIINEADLQYYVAQFKKSGFRGPLNWYRNMQRNSEWN 482
Query: 477 CKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQ 536
+ G KIL+PALMVTA KDFVL+P M++ ME+ IP+L RGHIE+C HWTQM++P VN
Sbjct: 483 ISAHGWKILVPALMVTAGKDFVLLPIMTKGMENLIPNLSRGHIEECSHWTQMERPAAVNG 542
Query: 537 ILIKWLDSDARNPPVVSKM 555
ILIKWL ++ N PV SK+
Sbjct: 543 ILIKWL-AEVHNLPVTSKL 560
>gb|EDL36006.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_b [Mus musculus]
Length = 501
Score = 752 bits (1942), Expect = 0.0, Method: Composition-based stats.
Identities = 373/503 (74%), Positives = 444/503 (88%), Gaps = 3/503 (0%)
Query: 54 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 113
MKG+IT SQW+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+
Sbjct: 1 MKGKITFSQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALK 60
Query: 114 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 173
KKGFTT I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTL
Sbjct: 61 KKGFTTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTL 120
Query: 174 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 233
KA P+EVVFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P CN
Sbjct: 121 KAKPNEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVP--CN 178
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
P+D+SHGYVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DM
Sbjct: 179 PNDVSHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDM 238
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
KGYG+SS+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVR
Sbjct: 239 KGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVR 298
Query: 354 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 413
AVASLNTPF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASD
Sbjct: 299 AVASLNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASD 358
Query: 414 E-SVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERN 472
E +++HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERN
Sbjct: 359 ETGFIAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERN 418
Query: 473 WKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPT 532
WKW+CK LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPT
Sbjct: 419 WKWSCKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPT 478
Query: 533 EVNQILIKWLDSDARNPPVVSKM 555
EVNQILIKWL ++ +NP V SK+
Sbjct: 479 EVNQILIKWLQTEVQNPSVTSKI 501
>gb|AAM28238.1| ovary-selective epoxide hydrolase [Mus musculus]
Length = 536
Score = 739 bits (1909), Expect = 0.0, Method: Composition-based stats.
Identities = 368/499 (73%), Positives = 439/499 (87%), Gaps = 3/499 (0%)
Query: 58 ITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGF 117
I S+W+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGF
Sbjct: 40 IHTSEWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGF 99
Query: 118 TTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASP 177
TT I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P
Sbjct: 100 TTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKP 159
Query: 178 SEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDM 237
+EVVFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P CNP+D+
Sbjct: 160 NEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVP--CNPNDV 217
Query: 238 SHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG 297
SHGYVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG
Sbjct: 218 SHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYG 277
Query: 298 ESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVAS 357
+SS+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVAS
Sbjct: 278 DSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVAS 337
Query: 358 LNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SV 416
LNTPF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE
Sbjct: 338 LNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGF 397
Query: 417 LSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWA 476
+++HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+
Sbjct: 398 IAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWS 457
Query: 477 CKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQ 536
CK LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQ
Sbjct: 458 CKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQ 517
Query: 537 ILIKWLDSDARNPPVVSKM 555
ILIKWL ++ +NP V SK+
Sbjct: 518 ILIKWLQTEVQNPSVTSKI 536
>gb|ABU95055.1| epoxide hydrolase 2C [Mus musculus]
Length = 488
Score = 731 bits (1887), Expect = 0.0, Method: Composition-based stats.
Identities = 363/490 (74%), Positives = 432/490 (88%), Gaps = 3/490 (0%)
Query: 67 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 126
M+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT I+TN W
Sbjct: 1 MDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNW 60
Query: 127 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 186
LDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P+EVVFLDD
Sbjct: 61 LDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDF 120
Query: 187 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 246
G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P CNP+D+SHGYVTVKP
Sbjct: 121 GSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVP--CNPNDVSHGYVTVKP 178
Query: 247 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 306
+RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS+PPEIE
Sbjct: 179 GIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIE 238
Query: 307 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 366
EY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNTPF+P +
Sbjct: 239 EYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPD 298
Query: 367 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSMHKVCEA 425
P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE +++HK E
Sbjct: 299 PDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEI 358
Query: 426 GGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKIL 485
GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK LGRKIL
Sbjct: 359 GGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKIL 418
Query: 486 IPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSD 545
+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILIKWL ++
Sbjct: 419 VPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTE 478
Query: 546 ARNPPVVSKM 555
+NP V SK+
Sbjct: 479 VQNPSVTSKI 488
>ref|NP_001028817.1| epoxide hydrolase 2, cytoplasmic [Gallus gallus]
gb|AAZ38461.1| soluble epoxide hydrolase [Gallus gallus]
Length = 562
Score = 709 bits (1831), Expect = 0.0, Method: Composition-based stats.
Identities = 314/562 (55%), Positives = 418/562 (74%), Gaps = 7/562 (1%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M R A+FDL GVL P + LG E + ALPR L D GG + ++M+G+ITL
Sbjct: 1 MARRFALFDLGGVLFGPGLQHFLGSCERSYALPRNFLRDVLFAGGSDSPHAKVMRGQITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQ ++E CR+ + TA + LP FSI +F++ + +N P+L+AA MLR+ GF T
Sbjct: 61 SQLFLEVDEGCRQHASTAGITLPTTFSIAHVFEEMAAKGTLNAPLLRAASMLRRNGFKTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
+ TN W+DD R + L+ ++ HFD LIESC+VG+ KP+P+IY + L+ L+A P EV
Sbjct: 121 VFTNNWVDDSMGRLFTSSLLTVVQRHFDLLIESCRVGLHKPDPRIYTYALEVLQAQPQEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
+FLDDIG NLKPAR++GM TILV+DTDT LKEL++++G+QLL PLPT+C+P+ MSHG
Sbjct: 181 IFLDDIGENLKPAREMGMATILVRDTDTVLKELQELSGVQLLQQEEPLPTTCDPATMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV ++P V+LHFVE+G GPA+CLCHGFPESW SWRYQIPALA AG+RV+A++MKGYGES+
Sbjct: 241 YVPIRPGVQLHFVEMGHGPAICLCHGFPESWLSWRYQIPALADAGFRVIALEMKGYGEST 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY E +CK++ FLDKLG+ QAVFIGHDWGG +VW MALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYSQEQICKDLTIFLDKLGIPQAVFIGHDWGGAVVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-----S 415
P+ PA+P + +E++K+ P+FDYQ YFQEPGVAEAELE+++ RT K+L R++ S
Sbjct: 361 PYRPADPTVDIVETMKSFPMFDYQFYFQEPGVAEAELEKDIGRTLKALIRSTRPEDRLHS 420
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
V + V E GGL V PE+ S ++ E+Q+Y+++F++SGFRGPLNWYRNM NW+W
Sbjct: 421 VPGLLGVQERGGLLVGFPEDIPESLILHGAELQYYIERFQRSGFRGPLNWYRNMRPNWRW 480
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 535
A + RKIL+PALMVTA KD VL+P MS+ ME+WIP L+RGH+E CGHWTQM++P +N
Sbjct: 481 ALSAKDRKILMPALMVTAGKDVVLLPSMSKGMEEWIPQLRRGHLEACGHWTQMERPAALN 540
Query: 536 QILIKWLDSDARNPP--VVSKM 555
+IL++WL+ + VS++
Sbjct: 541 RILVEWLEGLPPDGAMLRVSRL 562
>ref|NP_001008642.1| epoxide hydrolase 2, cytoplasmic [Danio rerio]
gb|AAH86714.1| Zgc:101645 [Danio rerio]
gb|AAI65172.1| Ephx2 protein [synthetic construct]
Length = 557
Score = 671 bits (1733), Expect = 0.0, Method: Composition-based stats.
Identities = 272/547 (49%), Positives = 369/547 (67%), Gaps = 7/547 (1%)
Query: 2 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLS 61
+A +F L G + P + + EE + +G + + K G + A R KG+ TL+
Sbjct: 1 MKKAVLFSLWGGVVTPQIGQAFQKFEETTGISKGFIKNVETKLGSDNALHRAEKGKTTLA 60
Query: 62 QWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAI 121
Q IP + C+K + + LP FS +++FD + N L AA +LR+ G T I
Sbjct: 61 QMIPEFDAECQKVAADQGLSLPAQFSTQKLFDDMGKV-EFNMTFLDAAAVLRRNGIATGI 119
Query: 122 LTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVV 181
L N W+DD A+R +A+++ L+ FD ++ SC G+ PEP +K L+ L P E +
Sbjct: 120 LANIWVDDTAQRGSIARVLSVLESRFDLVLRSCHAGVRIPEPDFFKHALEKLAVKPQEAL 179
Query: 182 FLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGY 241
+LD ++K A LG++ + V+D AL E++K+TGI++ T P SC+P +SHGY
Sbjct: 180 WLDVDEESVKAAEGLGIMAVQVKDVTEALTEIQKLTGIEV--TSDLQPPSCDPEKVSHGY 237
Query: 242 VTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSA 301
V +KP V++H+VE+G GP V LCHGFPESW+SWRYQIPALA AG+RVLA DMKGYG S+A
Sbjct: 238 VNIKPGVKIHYVEMGDGPPVLLCHGFPESWFSWRYQIPALADAGFRVLAPDMKGYGGSTA 297
Query: 302 PPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTP 361
PP+IEEY E + ++VTFLDK+ ++Q +GHDWGG+LVW MA F+PERVRAVASLNTP
Sbjct: 298 PPDIEEYSQEQIMLDLVTFLDKMAIAQVTLVGHDWGGVLVWNMAQFHPERVRAVASLNTP 357
Query: 362 FIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE----SVL 417
P +PN +P+E + A P+FDYQ+YFQ+PGVAEAELE+NL RTFK +F +S + L
Sbjct: 358 LFPVDPNTNPMEKLMAIPIFDYQIYFQKPGVAEAELEKNLKRTFKLMFISSSDTGGFPKL 417
Query: 418 SMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWAC 477
S VC+ GGLFV SP++P S M++ +QFY +Q+ KSGFRGPLNWYRN ERNW+W
Sbjct: 418 SPAGVCQRGGLFVGSPDDPPRSSMLSVSALQFYTEQYSKSGFRGPLNWYRNYERNWRWMV 477
Query: 478 KSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQI 537
KIL+PALMVTA KD VL+P + ME+ IP+L RGHIE+CGHWTQM++P E+N+I
Sbjct: 478 SRPRAKILMPALMVTAGKDPVLLPAFATGMENLIPNLSRGHIEECGHWTQMERPAELNKI 537
Query: 538 LIKWLDS 544
LI WL
Sbjct: 538 LISWLKE 544
>gb|ACC95977.1| soluble epoxide hydrolase-like protein 1 [Strongylocentrotus
purpuratus]
Length = 562
Score = 663 bits (1712), Expect = 0.0, Method: Composition-based stats.
Identities = 244/553 (44%), Positives = 346/553 (62%), Gaps = 10/553 (1%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M +A +FDL GVL P L + E L LP L A +G P+ A R+ +GE T
Sbjct: 5 MKKKAVLFDLGGVLFEP-PQNALRKYGEQLGLPGSFLEKAMIQGRPDNAFCRMERGESTA 63
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Q+ ++C+ S+ LPK+F+ +FD ++ + + ML A +L++ G TA
Sbjct: 64 RQFAEEFTKDCQTLSKEEGQVLPKDFNASSMFDTFMNIKMV-PDMLNAVSVLKQNGVKTA 122
Query: 121 ILTNTWLDDRAERDGLAQLMCELKM-HFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
+TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L L E
Sbjct: 123 AVTNNYIDDREQNSLGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKLGVKAEE 182
Query: 180 VVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSH 239
VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P S + + H
Sbjct: 183 AVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVFQEAKP--VSVHHERVPH 240
Query: 240 GYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGES 299
Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A AG+RV+AMDMKGYGES
Sbjct: 241 SYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAAAGFRVIAMDMKGYGES 300
Query: 300 SAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
S PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV AV +
Sbjct: 301 SNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVSAVGGIC 360
Query: 360 TPFIPANPNMSPLESIKANP-VFDYQLYFQEPGVAEAELEQNLSRTFKSLFRAS---DES 415
TPF PAN M+P E+I NP ++DYQLYF E G EAE+E N+ + K+ R E
Sbjct: 361 TPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRPLELKEI 420
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
S+ V GG+ P++ + S ++TE+++Q+YV+QFK G R LNWYR ME NWK+
Sbjct: 421 GFSVAGVRAKGGIMAGIPDDIN-STLLTEDDVQYYVKQFKTCGLRSMLNWYRTMEVNWKF 479
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 535
+++GRK+ +PALMVT D VL P +S+ M+ ++ +L R HIED GHW +++P ++N
Sbjct: 480 NHRAIGRKLYMPALMVTCAWDEVLPPSVSKFMDPFVVNLTRAHIEDSGHWASLEQPKKLN 539
Query: 536 QILIKWLDSDARN 548
+IL+ WL+ ++
Sbjct: 540 KILVDWLNKVHKD 552
>ref|XP_001521600.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic, partial
[Ornithorhynchus anatinus]
Length = 530
Score = 614 bits (1585), Expect = e-174, Method: Composition-based stats.
Identities = 301/498 (60%), Positives = 372/498 (74%), Gaps = 15/498 (3%)
Query: 64 IPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILT 123
+PL++E CR S A + LP FSI+ +FD+ S +IN PMLQAA+ LR +G+ T IL+
Sbjct: 2 VPLLDEACRDISAAAGLQLPTPFSIRRVFDEMGSGAEINIPMLQAAIALRNRGWKTGILS 61
Query: 124 NTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFL 183
NTW+DD +R A++ C L HFD +ESC VG+ KP+P IY L+ L P E V L
Sbjct: 62 NTWVDDSPQRGQWAEISCALAKHFDLRVESCHVGVAKPDPGIYLLALEALGVRPHEAVCL 121
Query: 184 DDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSD---MSHG 240
DD ANL+ A +LG+VT+ +DT AL++LE+VTG+Q+ TP P +P
Sbjct: 122 DDTEANLRAALELGLVTVQARDTAAALEKLEQVTGMQVWTTPVMPPPPLHPLSLAPWCSP 181
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
+ ++P V+LHFVE G+GPAVCLCHGFPESW+SWRYQIPALA AG+RV+A+DMKGYG+SS
Sbjct: 182 PLPIQPGVQLHFVEAGTGPAVCLCHGFPESWFSWRYQIPALADAGFRVIALDMKGYGDSS 241
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
AP IEEY E +CKE VTFLDKLG+SQAVFIGHDWGGM VW MALFYPERVRAVASLNT
Sbjct: 242 APQAIEEYSQEEMCKEAVTFLDKLGISQAVFIGHDWGGMFVWNMALFYPERVRAVASLNT 301
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+PA+P++ +E I+A PV DYQLYFQEPGVAEAELE NLSRT K L RASDE
Sbjct: 302 PFMPADPSVPAMERIRALPVCDYQLYFQEPGVAEAELEANLSRTLKLLIRASDE------ 355
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KV GGL V PE SR++ EE+++FYVQQF+KSGFRGPLNWYRNMERNW+W+C ++
Sbjct: 356 KVGSPGGLLVGMPEFSPTSRILKEEDLRFYVQQFEKSGFRGPLNWYRNMERNWRWSCTAV 415
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIP---HLKRGHIEDCGHWTQMDKPTEVNQI 537
GRKI++PALM+TA KD +L PQ S+HMEDW+ +RGHIE+CGHWTQM++PTE+NQI
Sbjct: 416 GRKIMVPALMITAGKDPILTPQTSRHMEDWVRSWGSGERGHIEECGHWTQMERPTELNQI 475
Query: 538 LIKWLDSDARNPPVVSKM 555
LIKWL P VSK+
Sbjct: 476 LIKWLKEL---PAGVSKL 490
>emb|CAG00866.1| unnamed protein product [Tetraodon nigroviridis]
Length = 535
Score = 592 bits (1527), Expect = e-167, Method: Composition-based stats.
Identities = 254/545 (46%), Positives = 341/545 (62%), Gaps = 19/545 (3%)
Query: 4 RAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQW 63
+A +F+ GV + GV E+ LP G L+ + +GA +R G +TL Q
Sbjct: 5 KAVLFNFWGVTVPSSPHGVCASLEKKRNLPEGFLSSLASRK--DGAMSRAEVGRLTLCQM 62
Query: 64 IPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISAR-KINRPMLQAALMLRKKGFTTAIL 122
P +E C + ++ LP ++S+ E+ DK A +N +L+ A +LR G+ TA+L
Sbjct: 63 APELEAECVQEAQARAAALPSDWSVAELVDKLREAMLDVNPAVLKMAAVLRSHGYLTAVL 122
Query: 123 TNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVF 182
N W+ D + G A+L+ L HFD +++SC+ G PE ++ L L + + ++
Sbjct: 123 ANHWVHDSGDTQGPARLLSHLGGHFDLVLQSCRTGHRVPEAAMFSAALQHLGVTSQQALW 182
Query: 183 LDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYV 242
LD +K A G+ ILV++ + AL +L TG+Q+ + + P CNP+++SHGYV
Sbjct: 183 LDADEDGVKAAEGEGLKAILVENAEDALSKLALHTGLQVDDAGSHTPP-CNPNEVSHGYV 241
Query: 243 TVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAP 302
++ V+ H+VE+G GP V LCHGFPESWYSWRYQIPALA AG+RVLA+DMKGYGES+AP
Sbjct: 242 AIRDGVKTHYVEMGEGPPVLLCHGFPESWYSWRYQIPALAYAGFRVLALDMKGYGESTAP 301
Query: 303 PEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPF 362
+I EY E +CK + Q +GHDWGG LVW MA F+PERVRA ASLNTP
Sbjct: 302 TDISEYTQEQMCK---------AIPQVTLVGHDWGGALVWSMAQFHPERVRAAASLNTPL 352
Query: 363 IPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE----SVLS 418
NP S L I+ +FDYQ+YFQE GVAEAELE+NL RTFK F E LS
Sbjct: 353 FEFNP--STLRKIQDLGIFDYQVYFQEQGVAEAELEENLERTFKVFFSRGSERDIRPPLS 410
Query: 419 MHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACK 478
VC GGL V PE+ LS M+TE ++QFYV +++ GFR PLNWYR ME N KW+
Sbjct: 411 TAGVCARGGLLVGQPEDVPLSSMLTEADLQFYVSRYRDQGFRRPLNWYRAMEANRKWSSS 470
Query: 479 SLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQIL 538
RK+L+PALMVTA +D VL+P +S+ ME+ IP+L RGHIE+ GHWTQMD+P E N+IL
Sbjct: 471 CPNRKVLVPALMVTAGRDPVLLPSLSEGMENMIPNLSRGHIEESGHWTQMDRPAETNRIL 530
Query: 539 IKWLD 543
I WL
Sbjct: 531 IGWLQ 535
>ref|XP_795168.2| PREDICTED: similar to Ephx2-prov protein [Strongylocentrotus
purpuratus]
Length = 507
Score = 591 bits (1525), Expect = e-167, Method: Composition-based stats.
Identities = 223/501 (44%), Positives = 320/501 (63%), Gaps = 9/501 (1%)
Query: 53 LMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALML 112
+ +GE T Q+ ++C+ S+ LPK+F+ +FD ++ + + ML A +L
Sbjct: 1 MERGESTARQFAEEFTKDCQTLSKEEGQVLPKDFNASSMFDTFMNIKMV-PDMLNAVSVL 59
Query: 113 RKKGFTTAILTNTWLDDRAERDGLAQLMCELKM-HFDFLIESCQVGMVKPEPQIYKFLLD 171
++ G TA +TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L
Sbjct: 60 KQNGVKTAAVTNNYIDDREQNSLGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALK 119
Query: 172 TLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTS 231
L E VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P S
Sbjct: 120 KLGVKAEEAVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVFQEAKP--VS 177
Query: 232 CNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAM 291
+ + H Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A G+RV+AM
Sbjct: 178 VHHERVPHSYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAATGFRVIAM 237
Query: 292 DMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPER 351
DMKGYGESS PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+R
Sbjct: 238 DMKGYGESSNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDR 297
Query: 352 VRAVASLNTPFIPANPNMSPLESIKANP-VFDYQLYFQEPGVAEAELEQNLSRTFKSLFR 410
V AV + TPF PAN M+P E+I NP ++DYQLYF E G EAE+E N+ + K+ R
Sbjct: 298 VSAVGGICTPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMR 357
Query: 411 AS---DESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYR 467
E S+ V GG+ P++ + S ++TE+++Q+YV+QFK G R LNWYR
Sbjct: 358 RPLELKEIGFSVAGVRAKGGIMAGIPDDIN-STLLTEDDVQYYVKQFKTCGLRSMLNWYR 416
Query: 468 NMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ 527
ME NWK+ +++GRK+ +PALMVT D VL P +S+ M+ ++ +L R HIED GHW
Sbjct: 417 TMEVNWKFNHRAIGRKLYMPALMVTCAWDEVLPPSVSKFMDPFVVNLTRAHIEDSGHWAS 476
Query: 528 MDKPTEVNQILIKWLDSDARN 548
+++P ++N+IL+ WL+ ++
Sbjct: 477 LEQPKKLNKILVDWLNKVHKD 497
>ref|XP_795076.2| PREDICTED: similar to Ephx2-prov protein, partial
[Strongylocentrotus purpuratus]
Length = 492
Score = 581 bits (1499), Expect = e-164, Method: Composition-based stats.
Identities = 223/515 (43%), Positives = 307/515 (59%), Gaps = 32/515 (6%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M +A +FDL GVL P L + E L LP D F
Sbjct: 5 MKKKAVLFDLGGVLFEP-PQNALRKYGEQLGLPG---QDLF------------------- 41
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Q+ ++C+ S+ LPK+F+ +FD ++ + + ML A +L++ G TA
Sbjct: 42 -QFAEEFTKDCQTVSKEEGQVLPKDFNASSMFDTFMNIKMV-PDMLNAVSVLKQNGVKTA 99
Query: 121 ILTNTWLDDRAERDGLAQLMCELKM-HFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
+TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L L E
Sbjct: 100 AVTNNYIDDREQNSVGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKLGVKAEE 159
Query: 180 VVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSH 239
VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P S + + H
Sbjct: 160 AVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVCQEAKP--VSVHHERVPH 217
Query: 240 GYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGES 299
Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A AG+RV+AMDMKGYGES
Sbjct: 218 SYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAAAGFRVIAMDMKGYGES 277
Query: 300 SAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
S PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV AV +
Sbjct: 278 SNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVSAVGGIC 337
Query: 360 TPFIPANPNMSPLESIKANP-VFDYQLYFQEPGVAEAELEQNLSRTFKSLFRAS---DES 415
TPF PAN M+P E+I NP ++DYQLYF E G EAE+E N+ + K+ R E
Sbjct: 338 TPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRPLELKEI 397
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
S+ V GG+ P++ LS ++TE+++Q+YV+QFK G R LNWYR ME NWK+
Sbjct: 398 GFSVAGVRAKGGIMAGIPDDIKLSTLLTEDDLQYYVKQFKTCGLRSMLNWYRTMEVNWKF 457
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDW 510
+++GRK+ +PALMVT D VL P S+ M+ +
Sbjct: 458 NHRAIGRKLYMPALMVTCAGDAVLPPSASKFMDPF 492
>ref|XP_001190554.1| PREDICTED: similar to Ephx2-prov protein [Strongylocentrotus
purpuratus]
Length = 595
Score = 581 bits (1499), Expect = e-164, Method: Composition-based stats.
Identities = 223/515 (43%), Positives = 307/515 (59%), Gaps = 32/515 (6%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M +A +FDL GVL P L + E L LP D F
Sbjct: 5 MKKKAVLFDLGGVLFEP-PQNALRKYGEQLGLPG---QDLF------------------- 41
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Q+ ++C+ S+ LPK+F+ +FD ++ + + ML A +L++ G TA
Sbjct: 42 -QFAEEFTKDCQTVSKEEGQVLPKDFNASSMFDTFMNIKMV-PDMLNAVSVLKQNGVKTA 99
Query: 121 ILTNTWLDDRAERDGLAQLMCELKM-HFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
+TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L L E
Sbjct: 100 AVTNNYIDDREQNSVGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKLGVKAEE 159
Query: 180 VVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSH 239
VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P S + + H
Sbjct: 160 AVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVCQEAKP--VSVHHERVPH 217
Query: 240 GYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGES 299
Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A AG+RV+AMDMKGYGES
Sbjct: 218 SYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAAAGFRVIAMDMKGYGES 277
Query: 300 SAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
S PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV AV +
Sbjct: 278 SNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVSAVGGIC 337
Query: 360 TPFIPANPNMSPLESIKANP-VFDYQLYFQEPGVAEAELEQNLSRTFKSLFRAS---DES 415
TPF PAN M+P E+I NP ++DYQLYF E G EAE+E N+ + K+ R E
Sbjct: 338 TPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRPLELKEI 397
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
S+ V GG+ P++ LS ++TE+++Q+YV+QFK G R LNWYR ME NWK+
Sbjct: 398 GFSVAGVRAKGGIMAGIPDDIKLSTLLTEDDLQYYVKQFKTCGLRSMLNWYRTMEVNWKF 457
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDW 510
+++GRK+ +PALMVT D VL P S+ M+ +
Sbjct: 458 NHRAIGRKLYMPALMVTCAGDAVLPPSASKFMDPF 492
>ref|XP_001184789.1| PREDICTED: similar to Ephx2-prov protein [Strongylocentrotus
purpuratus]
Length = 707
Score = 581 bits (1498), Expect = e-164, Method: Composition-based stats.
Identities = 225/523 (43%), Positives = 324/523 (61%), Gaps = 11/523 (2%)
Query: 31 ALPRGLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKE 90
L + + +G TR K E ++ ++C+ S+ LPK+F+
Sbjct: 181 GLCYVFIYRSVAMVPCDGNITRQRKEE--NQRFAEEFTKDCQTLSKEEGQVLPKDFNASS 238
Query: 91 IFDKAISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKM-HFDF 149
+FD ++ + + ML A +L++ G TA +TN ++DDR + A +M L +FD
Sbjct: 239 MFDTFMNIKMV-PDMLNAVSVLKQNGVKTAAVTNNYIDDREQNSLGAGVMTTLSSFYFDH 297
Query: 150 LIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTA 209
+ESC+ G KP+ I+ L L E VFLDD+G N+K AR++G+ T+LV+DT A
Sbjct: 298 FVESCRFGKRKPDQSIFNEALKKLGVKAEEAVFLDDLGPNVKAAREMGISTVLVKDTSAA 357
Query: 210 LKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPE 269
LKEL++VTGI + P S + + H Y T + V+ H+V++GSGP V CHGFPE
Sbjct: 358 LKELQEVTGIDVFQEAKP--VSVHHERVPHSYATTRSGVKFHYVDIGSGPPVIFCHGFPE 415
Query: 270 SWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQA 329
SWY W+ QIPA+A G+RV+AMDMKGYGESS PPEIEEY +E +CK+M F+D L + QA
Sbjct: 416 SWYEWKSQIPAVAATGFRVIAMDMKGYGESSNPPEIEEYTLERMCKDMAEFMDTLCIPQA 475
Query: 330 VFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANP-VFDYQLYFQ 388
FIGHDWGG VW A YP+RV AV + TPF PAN M+P E+I NP ++DYQLYF
Sbjct: 476 TFIGHDWGGFFVWNYATHYPDRVSAVGGICTPFFPANDTMNPWENINKNPGLYDYQLYFN 535
Query: 389 EPGVAEAELEQNLSRTFKSLFRAS---DESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEE 445
E G EAE+E N+ + K+ R E S+ V GG+ P++ + S ++TE+
Sbjct: 536 EVGPPEAEIEANVEKFVKAFMRRPLELKEIGFSVAGVRAKGGIMAGIPDDIN-STLLTED 594
Query: 446 EIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQ 505
++Q+YV+QFK G R LNWYR ME NWK+ +++GRK+ +PALMVT D VL P +S+
Sbjct: 595 DVQYYVKQFKTCGLRSMLNWYRTMEVNWKFNHRAIGRKLYMPALMVTCAWDEVLPPSVSK 654
Query: 506 HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARN 548
M+ ++ +L R HIED GHW +++P ++N+IL+ WL+ ++
Sbjct: 655 FMDPFVVNLTRAHIEDSGHWASLEQPKKLNKILVDWLNKVHKD 697
>ref|XP_001641873.1| predicted protein [Nematostella vectensis]
gb|EDO49810.1| predicted protein [Nematostella vectensis]
Length = 548
Score = 557 bits (1435), Expect = e-156, Method: Composition-based stats.
Identities = 218/555 (39%), Positives = 326/555 (58%), Gaps = 30/555 (5%)
Query: 2 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLS 61
+ A+FDL GV+A F + + +P LL F +L G+I+LS
Sbjct: 1 MFKLAIFDLGGVVATSLKFAI-EHYAWKMGVPYSLLQKLFLPSNENQPMWQLETGKISLS 59
Query: 62 QWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAI 121
Q+ E +E + LP FS+K +FD+ K+ ML AA L+ GF T I
Sbjct: 60 QFFVSASELISNLAEEEGIKLPPRFSLKTLFDQLYKTIKVVPEMLNAAAALKANGFRTCI 119
Query: 122 LTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVV 181
++N W DD ++ L ++ +FD ESC++G+ KP+P++YK + K P+EV+
Sbjct: 120 VSNNWTDDTETGQHVSGL-SLIRPYFDDFFESCKIGIRKPDPEMYKLVCKKFKVQPNEVL 178
Query: 182 FLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGY 241
FLDD+ +NL PA+++GM TILV+D +AL+ ++++TGI +L +C PS + H
Sbjct: 179 FLDDLPSNLAPAKEMGMATILVKDPISALRTVKEITGIDVLKAYP--TPACTPSSVPHSI 236
Query: 242 VTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVL---------AMD 292
V +K + +H+V++G G + L HGFPE WY W+YQ ++ Y VL A
Sbjct: 237 VQLKTGIMMHYVDIGHGHPIILLHGFPELWYIWKYQGTIIS---YGVLFEAKSDAKLACT 293
Query: 293 MKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERV 352
Y S ++ +++++ +D L L Q IGHDWGGM+ W +AL +P+R+
Sbjct: 294 QLLYSPSDKI---------IVFQDIISLMDLLLLRQVAVIGHDWGGMVAWDLALHHPDRI 344
Query: 353 RAVASLNTPFIPANPNMSPLESIKANP-VFDYQLYFQEPGVAEAELEQNLSRTFKSLFRA 411
RAVA++ TPF+P NP+++PL +KA P VF YQLYF + G EAE E++L RTFK R
Sbjct: 345 RAVANM-TPFMPPNPDINPLLGLKAKPGVFQYQLYFHQEGPPEAEFEKDLRRTFKLFLRN 403
Query: 412 SDESV---LSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRN 468
+ E LS V E GG FV +PE+ S M+TEE++ ++V+ F+K+GFRGPLNWYRN
Sbjct: 404 ASEMEQIKLSTSDVLERGGFFVGTPEKVERSCMITEEDLDYFVENFRKTGFRGPLNWYRN 463
Query: 469 MERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQM 528
ME +WKW K RKIL P LM+T+ KD V++P + +M +P+L HIE+ H+T +
Sbjct: 464 MEVDWKWNLKIHPRKILQPVLMITSGKDPVILPAFAANMGAHVPNLSLAHIEESSHFTPI 523
Query: 529 DKPTEVNQILIKWLD 543
D+P E+N +L+ WL
Sbjct: 524 DRPLELNNMLLDWLK 538
>gb|ACC95978.1| soluble epoxide hydrolase-like protein 2 [Strongylocentrotus
purpuratus]
Length = 561
Score = 509 bits (1312), Expect = e-142, Method: Composition-based stats.
Identities = 193/556 (34%), Positives = 298/556 (53%), Gaps = 28/556 (5%)
Query: 3 LRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQ 62
+ +FDL GV+ P +L EEA LPR + + +G RL +GEIT++Q
Sbjct: 4 KKVVLFDLGGVIVTPPQRALLKYCEEA-GLPRNFIFNVISQGRANNTFARLERGEITVTQ 62
Query: 63 WIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAIL 122
+ E+ CR+ +E + +P +FS E+ + + ML A +L++ G T L
Sbjct: 63 FATEFEQECRRVAEAQSLVIPDSFSATEMVN--FKDPDLIPEMLNAVAVLKENGVQTCAL 120
Query: 123 TNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVF 182
TN ++D+ + R A + +FD +ESC++G+ KP+P I+ L L A S+ VF
Sbjct: 121 TNNYIDNTSNRAYAAGGLTAFTFYFDEFVESCRLGIRKPDPNIFHEALARLGAEASQAVF 180
Query: 183 LDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYV 242
LDD N K A LG+ +ILVQD TAL++L+ VTGI + P+ + +P +++H YV
Sbjct: 181 LDDSEVNTKAAEALGITSILVQDPKTALEQLKIVTGIDVFKQAGPI--TVHPDEVTHSYV 238
Query: 243 TVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAP 302
T + +VR HF ELGSGP V LCH F E W +WR +P LA AG+R +A+D+KG+GESS P
Sbjct: 239 TTRSKVRFHFTELGSGPPVVLCHDFEEDWEAWRSLMPELAIAGFRAIALDLKGFGESSKP 298
Query: 303 PEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPF 362
+ E+Y +++LC++M FLD LG++Q IG G W A +RVRAVA +NT
Sbjct: 299 TDTEQYTLKILCRDMTEFLDALGIAQVTLIGKGMGSAFAWTFANHTTDRVRAVAGINTSP 358
Query: 363 IPANPNMSPLESIKANPVFDYQLYFQEPGV-----AEAELEQNLSRTFKSLFRASDESVL 417
P+ + IK + F+ + E+EQ ++ S ++
Sbjct: 359 SVVIPDTLYGDQIKRIGSLQDYIKFRHCDRNNNNNPDIEMEQ----FYRIATCHSSDTNP 414
Query: 418 SMHKVCEAGGLFVNSPE---EPSLSRMVTEEEIQ-------FYVQQFKKSGFRGPLNWYR 467
+ H C G+ V E + S++ + E + + + KS RG NW+R
Sbjct: 415 TKHDRC-LQGIDVKDFELSTKASMNCLCIEADKRGKKQLGGHHRSTKSKSKSRGA-NWFR 472
Query: 468 NMERNWKWACKSLGRKILIPALMVT-AEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWT 526
N NW+W + GR +LIPAL+VT + VP +S+ ++ WIP ++ H+ C T
Sbjct: 473 NNAANWEWNRRLNGRMLLIPALVVTSGQGSPKDVPDVSE-LKKWIPEVEHSHVSGCEIKT 531
Query: 527 QMDKPTEVNQILIKWL 542
++ +E+N+IL KWL
Sbjct: 532 DRERSSELNRILRKWL 547
>emb|CAH91370.1| hypothetical protein [Pongo abelii]
Length = 372
Score = 498 bits (1283), Expect = e-139, Method: Composition-based stats.
Identities = 310/351 (88%), Positives = 317/351 (90%), Gaps = 3/351 (0%)
Query: 205 DTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLC 264
T+ AL + T+ M +P VRLHFVELGSGPAVCLC
Sbjct: 25 RTEEALALPRGLLNDAFQKGGPEGATT---RLMRGEITLSQPGVRLHFVELGSGPAVCLC 81
Query: 265 HGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKL 324
HGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKL
Sbjct: 82 HGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKL 141
Query: 325 GLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQ 384
GLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPN+SPLESIKANPVFDYQ
Sbjct: 142 GLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNVSPLESIKANPVFDYQ 201
Query: 385 LYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTE 444
LYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFV+SPEEPSLSRMVTE
Sbjct: 202 LYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVSSPEEPSLSRMVTE 261
Query: 445 EEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMS 504
EEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMS
Sbjct: 262 EEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMS 321
Query: 505 QHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM 555
+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNP VVSKM
Sbjct: 322 KHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPLVVSKM 372
Score = 98.0 bits (243), Expect = 2e-18, Method: Composition-based stats.
Identities = 61/62 (98%), Positives = 62/62 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQ 62
SQ
Sbjct: 61 SQ 62
>ref|XP_001181957.1| PREDICTED: similar to soluble epoxide hydrolase, partial
[Strongylocentrotus purpuratus]
Length = 527
Score = 467 bits (1202), Expect = e-129, Method: Composition-based stats.
Identities = 175/519 (33%), Positives = 270/519 (52%), Gaps = 17/519 (3%)
Query: 35 GLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDK 94
+ + +G RL +GEIT++Q+ E+ CR+ +E + +P +FS E+ +
Sbjct: 1 NFIFNVISQGRANNTFARLERGEITVTQFATEFEQECRRVAEAQSLVIPDSFSATEMVN- 59
Query: 95 AISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESC 154
+ ML A +L++ G T LTN ++D+ + R A + +FD +ESC
Sbjct: 60 -FKDPDLIPEMLNAVAVLKENGVQTCALTNNYIDNTSNRAYAAGGLTAFTFYFDEFVESC 118
Query: 155 QVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELE 214
++G+ KP+P I+ L L A S+ VFLDD N K A LG+ +ILVQD TAL++L+
Sbjct: 119 RLGIRKPDPNIFHEALARLGAEASQAVFLDDSEVNTKAAEALGITSILVQDPKTALEQLK 178
Query: 215 KVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSW 274
VTGI + P+ + +P +++H YVT + +VR HF ELGSGP V LCH F E W +W
Sbjct: 179 IVTGIDVFKQAGPI--TVHPDEVTHSYVTTRSKVRFHFTELGSGPPVVLCHDFEEDWEAW 236
Query: 275 RYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGH 334
R +P LA AG+R +A+D+KG+GESS P + E+Y +++LC++M FLD LG++Q IG
Sbjct: 237 RSLMPELAIAGFRAIALDLKGFGESSKPTDTEQYTLKILCRDMTEFLDALGIAQVTLIGK 296
Query: 335 DWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAE 394
G W A +RVRAVA +NT P+ + IK + F+
Sbjct: 297 GMGSAFAWTFANHTTDRVRAVAGINTSPSVVIPDTFYGDQIKRIGSLQDYIKFRHCDRNN 356
Query: 395 AELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPE---EPSLSRMVTEEEIQ--- 448
F + G+ V E + S++ + E + +
Sbjct: 357 NNNPDIEMEQFYRIATCHSSDTNPAKDDRCLQGIDVKDFELSTKASMNCLCIEADKREKK 416
Query: 449 ----FYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVT-AEKDFVLVPQM 503
+ KS RG NW+RN NW+W + GR +LIPAL+VT + VP +
Sbjct: 417 QLGGHHRSTKSKSKSRGA-NWFRNNAANWEWNRRLNGRMLLIPALVVTSGQGSPKDVPDV 475
Query: 504 SQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWL 542
S+ ++ WIP ++ H+ C T ++ +E+N+IL KWL
Sbjct: 476 SE-LKKWIPEVEHSHVSGCEIKTDRERSSELNRILRKWL 513
>ref|YP_629896.1| putative epoxide hydrolase [Myxococcus xanthus DK 1622]
gb|ABF91519.1| putative epoxide hydrolase [Myxococcus xanthus DK 1622]
Length = 318
Score = 358 bits (920), Expect = 6e-97, Method: Composition-based stats.
Identities = 120/317 (37%), Positives = 170/317 (53%), Gaps = 8/317 (2%)
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
+D++H V + LH E GSGP V L HG+PESWYSWR+Q+PALA AGY +A D+
Sbjct: 1 MADITHRTVKTNG-INLHLAEAGSGPLVLLLHGWPESWYSWRHQLPALAAAGYHAVAPDV 59
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
+GYG+S P IE Y M+ L + V LD LG A+ IGHDWG + W A +P+R R
Sbjct: 60 RGYGQSDKPEAIEAYSMKQLVGDAVGLLDALGERTAIVIGHDWGSAIAWNCAALHPDRFR 119
Query: 354 AVASLNTPFIPANPNMSPLESIKAN--PVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRA 411
AV ++ P + P M P++ + + Y LYFQEPGVAEAE E ++ RT +++
Sbjct: 120 AVVGMSVPHLGRAP-MPPMQLFQRMFGEKWFYILYFQEPGVAEAEFEADVPRTVRAILTG 178
Query: 412 SDESVLSMHKVCE---AGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRN 468
+ ++ V G +L +TE ++ ++ ++ SGFRG LN YRN
Sbjct: 179 TPGFDVTNPAVLAKKKGEGFLARLDVPETLPGWLTEADVAYFAKELAGSGFRGGLNRYRN 238
Query: 469 MERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLK-RGHIEDCGHWTQ 527
M+R+W + I PAL + EKD V M+ +P+L I GHW Q
Sbjct: 239 MDRDWHELPELATAVISQPALYIVGEKDPVRAFSPVDPMKALVPNLADIHVIPGAGHWVQ 298
Query: 528 MDKPTEVNQILIKWLDS 544
+ EVN L+ +L
Sbjct: 299 QEHAAEVNAALLAFLKK 315
>gb|EEJ94100.1| predicted hydrolase or acyltransferase of alpha/beta superfamily
[Thermomonospora curvata DSM 43183]
Length = 350
Score = 356 bits (915), Expect = 2e-96, Method: Composition-based stats.
Identities = 112/315 (35%), Positives = 169/315 (53%), Gaps = 7/315 (2%)
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
++++H + V + +H E GSGP V L HGFPE WYSWR+Q+ ALA+AG+ +A D
Sbjct: 34 MAEITHRTIEVNG-LNMHVAEAGSGPLVVLLHGFPECWYSWRHQLTALAEAGFHAVAPDQ 92
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
+GY + P + EY + L ++V + LG +AV +GHDWG + W+ A F P+ VR
Sbjct: 93 RGYARTGGPQRVAEYSILHLVGDVVALIAALGEERAVVVGHDWGAPVAWHTAQFRPDLVR 152
Query: 354 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS-LFRAS 412
V L+ P + Y + FQEP EA E++++ TF+ L+ S
Sbjct: 153 GVVGLSVHPRPRTSRPPVAVMREQFGEGFYMVAFQEPKRPEAAFERDVADTFRRTLYALS 212
Query: 413 DESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERN 472
++ + V E G P L +TE++I Y +F SGF GPLNWYRN++RN
Sbjct: 213 GDAPGMLPVVPEGGSFLDVCPAPERLPGWLTEDDIAVYAAEFAASGFTGPLNWYRNLDRN 272
Query: 473 WKWACKSLGRKILIPALMVTAEKDFVL----VPQMSQHMEDWIPHLK-RGHIEDCGHWTQ 527
W+ I PAL + E+D VL V + + +++P L+ + CGHWTQ
Sbjct: 273 WELTAAWHRAPITPPALYIAGERDMVLAGPGVKERLSRLREFVPDLRDIVLLPGCGHWTQ 332
Query: 528 MDKPTEVNQILIKWL 542
++P EVN+ L+ +L
Sbjct: 333 QERPREVNEALLAFL 347
>ref|NP_771160.1| epoxide hydrolase [Bradyrhizobium japonicum USDA 110]
dbj|BAC49785.1| epoxide hydrolase [Bradyrhizobium japonicum USDA 110]
Length = 318
Score = 356 bits (913), Expect = 4e-96, Method: Composition-based stats.
Identities = 117/307 (38%), Positives = 175/307 (57%), Gaps = 8/307 (2%)
Query: 245 KPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPE 304
+ L E G GP V LCHG+PE YSWR+QIPALA AG+ V+A DM+GYG+S+AP +
Sbjct: 9 ANGIDLFIREAGQGPLVVLCHGWPELSYSWRHQIPALAAAGFHVVAPDMRGYGQSAAPAD 68
Query: 305 IEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIP 364
+ Y + ++V + LG S+A+ +GHDWG + W+ ALF P+ AVA L+ P P
Sbjct: 69 VSAYSIFDTVGDIVGLVQALGESKAMVVGHDWGAPVAWHAALFRPDIFTAVAGLSVP-PP 127
Query: 365 ANPNMSPLESIKANPVF-DYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVC 423
PL+ ++ V Y YFQ PGVAE ELE++++RT + + + S
Sbjct: 128 FRGRGKPLDLLRQGGVTNFYWQYFQVPGVAEVELERDVARTMRIVLGGRGLADPSAAMFV 187
Query: 424 EAG-GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGR 482
+ G G ++ + L ++E ++ ++ + F+KSGFRG LNWYRN++RNW+
Sbjct: 188 QEGKGFLGHATADEPLPDWLSEADLAYFTETFRKSGFRGGLNWYRNLDRNWELTAPWQDA 247
Query: 483 KILIPALMVTAEKDFVLV----PQMSQHMEDWIPHLKRG-HIEDCGHWTQMDKPTEVNQI 537
+I P+L + KD V+ + +E +P+L R IE GHW Q ++P EVN
Sbjct: 248 QIHQPSLFIAGSKDAVITGLIGAKRVNELERVLPNLTRKLIIEGAGHWVQQERPDEVNAA 307
Query: 538 LIKWLDS 544
L+K+L
Sbjct: 308 LVKFLRE 314
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|XP_001163779.1| PREDICTED: epoxide hydrolase 2, cytopla... 843 0.0
ref|NP_001970.2| epoxide hydrolase 2, cytoplasmic [Homo sap... 840 0.0
gb|AAP36260.1| Homo sapiens epoxide hydrolase 2, cytoplasmi... 840 0.0
gb|AAG14967.1|AF233335_1 soluble epoxide hydrolase [Homo sa... 838 0.0
gb|AAG14968.1|AF233336_1 soluble epoxide hydrolase [Homo sa... 837 0.0
gb|EAW63547.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 832 0.0
ref|XP_001163896.1| PREDICTED: epoxide hydrolase 2, cytopla... 828 0.0
gb|AAA02756.1| cytosolic epoxide hydrolase 828 0.0
ref|XP_001109474.1| PREDICTED: similar to epoxide hydrolase... 817 0.0
ref|NP_001069002.1| epoxide hydrolase 2, cytoplasmic [Bos t... 809 0.0
ref|NP_001001641.1| soluble epoxide hydrolase [Sus scrofa] ... 796 0.0
ref|XP_001492725.1| PREDICTED: similar to soluble epoxide h... 792 0.0
ref|XP_534566.1| PREDICTED: similar to epoxide hydrolase 2,... 791 0.0
ref|XP_857471.1| PREDICTED: similar to epoxide hydrolase 2,... 790 0.0
ref|XP_857554.1| PREDICTED: similar to epoxide hydrolase 2,... 788 0.0
ref|XP_857430.1| PREDICTED: similar to epoxide hydrolase 2,... 787 0.0
gb|AAH85732.1| Epoxide hydrolase 2, cytoplasmic [Rattus nor... 778 0.0
ref|NP_075225.1| epoxide hydrolase 2, cytoplasmic [Rattus n... 778 0.0
emb|CAA85471.1| Epoxide Hydrolase [Mus musculus] 775 0.0
ref|NP_031966.2| epoxide hydrolase 2, cytoplasmic [Mus musc... 774 0.0
dbj|BAE25172.1| unnamed protein product [Mus musculus] 773 0.0
ref|XP_001163527.1| PREDICTED: epoxide hydrolase 2, cytopla... 773 0.0
gb|EAW63549.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 770 0.0
ref|XP_001163861.1| PREDICTED: epoxide hydrolase 2, cytopla... 762 0.0
ref|XP_001163819.1| PREDICTED: epoxide hydrolase 2, cytopla... 750 0.0
ref|XP_001163565.1| PREDICTED: epoxide hydrolase 2, cytopla... 750 0.0
gb|EAW63551.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 748 0.0
ref|NP_001087143.1| epoxide hydrolase 2, cytoplasmic [Xenop... 738 0.0
ref|NP_001006912.1| epoxide hydrolase 2, cytoplasmic [Xenop... 736 0.0
gb|EDL85377.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 727 0.0
ref|XP_001380051.1| PREDICTED: similar to soluble epoxide h... 725 0.0
gb|EDL36006.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 715 0.0
gb|AAM28238.1| ovary-selective epoxide hydrolase [Mus muscu... 703 0.0
gb|ABU95055.1| epoxide hydrolase 2C [Mus musculus] 694 0.0
ref|NP_001028817.1| epoxide hydrolase 2, cytoplasmic [Gallu... 691 0.0
gb|ACC95977.1| soluble epoxide hydrolase-like protein 1 [St... 661 0.0
ref|NP_001008642.1| epoxide hydrolase 2, cytoplasmic [Danio... 653 0.0
ref|XP_001521600.1| PREDICTED: similar to epoxide hydrolase... 601 e-170
ref|XP_795168.2| PREDICTED: similar to Ephx2-prov protein [... 584 e-165
ref|XP_795076.2| PREDICTED: similar to Ephx2-prov protein, ... 576 e-162
ref|XP_001190554.1| PREDICTED: similar to Ephx2-prov protei... 576 e-162
ref|XP_001184789.1| PREDICTED: similar to Ephx2-prov protei... 572 e-161
emb|CAG00866.1| unnamed protein product [Tetraodon nigrovir... 567 e-160
ref|XP_001641873.1| predicted protein [Nematostella vectens... 552 e-155
gb|ACC95978.1| soluble epoxide hydrolase-like protein 2 [St... 527 e-148
ref|XP_001181957.1| PREDICTED: similar to soluble epoxide h... 486 e-135
emb|CAH91370.1| hypothetical protein [Pongo abelii] 455 e-126
gb|EEJ94100.1| predicted hydrolase or acyltransferase of al... 386 e-105
ref|NP_771160.1| epoxide hydrolase [Bradyrhizobium japonicu... 384 e-105
ref|YP_629896.1| putative epoxide hydrolase [Myxococcus xan... 382 e-104
ref|YP_486290.1| Alpha/beta hydrolase [Rhodopseudomonas pal... 381 e-104
dbj|BAD13534.1| soluble epoxide hydrolase [Citrus jambhiri] 380 e-103
ref|NP_567228.1| epoxide hydrolase, putative [Arabidopsis t... 378 e-103
gb|ABN08020.1| Epoxide hydrolase [Medicago truncatula] 377 e-102
ref|NP_767754.1| epoxide hydrolase [Bradyrhizobium japonicu... 377 e-102
ref|NP_001042621.1| Os01g0255000 [Oryza sativa (japonica cu... 376 e-102
gb|ABK93786.1| unknown [Populus trichocarpa] 376 e-102
ref|YP_569843.1| alpha/beta hydrolase fold [Rhodopseudomona... 376 e-102
emb|CAO44814.1| unnamed protein product [Vitis vinifera] 375 e-102
emb|CAO17500.1| unnamed protein product [Vitis vinifera] 375 e-102
ref|ZP_02299346.1| alpha/beta hydrolase fold [Rhodopseudomo... 375 e-102
emb|CAO44811.1| unnamed protein product [Vitis vinifera] 374 e-102
gb|ABK21215.1| unknown [Picea sitchensis] 373 e-101
ref|NP_948116.1| epoxide hydrolase [Rhodopseudomonas palust... 373 e-101
emb|CAO44812.1| unnamed protein product [Vitis vinifera] 372 e-101
emb|CAO40040.1| unnamed protein product [Vitis vinifera] 371 e-100
gb|AAM28292.1| epoxide hydrolase [Ananas comosus] 371 e-100
ref|NP_824987.1| epoxide hydrolase [Streptomyces avermitili... 369 e-100
ref|YP_001853373.1| epoxide hydrolase EphA [Mycobacterium m... 368 e-100
ref|YP_907699.1| epoxide hydrolase EphA [Mycobacterium ulce... 367 1e-99
dbj|BAA09852.1| Epoxide hydrolase [Glycine max] >gi|2764804... 367 2e-99
emb|CAA55294.1| epoxide hydrolase [Glycine max] 366 2e-99
gb|ABN08024.1| Epoxide hydrolase [Medicago truncatula] 366 4e-99
ref|NP_821315.1| epoxide hydrolase [Streptomyces avermitili... 366 4e-99
ref|NP_187211.1| epoxide hydrolase, putative [Arabidopsis t... 366 4e-99
ref|YP_001310928.1| alpha/beta hydrolase fold [Clostridium ... 365 5e-99
ref|NP_959380.1| EphA [Mycobacterium avium subsp. paratuber... 365 6e-99
ref|YP_001240076.1| Putative epoxide hydrolase [Bradyrhizob... 364 1e-98
emb|CAO70601.1| unnamed protein product [Vitis vinifera] 363 2e-98
ref|NP_190669.1| epoxide hydrolase, putative [Arabidopsis t... 362 5e-98
gb|ABN08021.1| Epoxide hydrolase [Medicago truncatula] 362 5e-98
ref|YP_001205815.1| epoxide hydrolase [Bradyrhizobium sp. O... 361 7e-98
emb|CAN77654.1| hypothetical protein [Vitis vinifera] 360 2e-97
ref|NP_001051780.1| Os03g0829100 [Oryza sativa (japonica cu... 358 6e-97
ref|YP_879819.1| hydrolase, alpha/beta fold family protein ... 358 9e-97
ref|XP_001753609.1| predicted protein [Physcomitrella paten... 358 9e-97
ref|NP_001042622.1| Os01g0255100 [Oryza sativa (japonica cu... 358 9e-97
ref|YP_692156.1| hydrolase, alpha/beta fold family [Alcaniv... 357 1e-96
emb|CAG44464.1| putative epoxide hydrolase [Streptomyces ri... 357 1e-96
gb|ABK94011.1| unknown [Populus trichocarpa] 357 2e-96
ref|ZP_01618404.1| epoxide hydrolase [marine gamma proteoba... 357 2e-96
gb|AAO27849.1|AF482450_1 soluble epoxide hydrolase [Euphorb... 356 2e-96
ref|NP_218134.1| PROBABLE EPOXIDE HYDROLASE EPHA (EPOXIDE H... 356 3e-96
ref|YP_001204572.1| putative epoxide hydrolase [Bradyrhizob... 355 4e-96
ref|YP_781780.1| alpha/beta hydrolase fold [Rhodopseudomona... 355 4e-96
ref|YP_001803894.1| unknown [Cyanothece sp. ATCC 51142] >gi... 355 6e-96
gb|EAZ11286.1| hypothetical protein OsJ_001111 [Oryza sativ... 354 9e-96
emb|CAO48291.1| unnamed protein product [Vitis vinifera] 354 1e-95
gb|AAA81890.1| epoxide hydrolase 353 2e-95
ref|YP_001413763.1| alpha/beta hydrolase fold [Parvibaculum... 353 3e-95
emb|CAD30841.1| soluble epoxide hydrolase [Brassica napus] 352 5e-95
ref|NP_001051781.1| Os03g0829200 [Oryza sativa (japonica cu... 351 1e-94
gb|EAY92418.1| hypothetical protein OsI_013651 [Oryza sativ... 350 2e-94
ref|XP_001152592.1| PREDICTED: abhydrolase domain containin... 350 2e-94
ref|YP_321204.1| Alpha/beta hydrolase fold [Anabaena variab... 350 2e-94
ref|NP_001069323.2| abhydrolase domain containing 7 [Bos ta... 349 3e-94
sp|Q8IUS5|ABHD7_HUMAN Abhydrolase domain-containing protein... 349 4e-94
ref|YP_001238893.1| putative epoxide hydrolase [Bradyrhizob... 349 5e-94
ref|NP_420043.1| epoxide hydrolase [Caulobacter crescentus ... 349 5e-94
ref|XP_001098374.1| PREDICTED: similar to abhydrolase domai... 348 6e-94
ref|YP_001701281.1| Probable epoxide hydrolase EphA [Mycoba... 348 6e-94
emb|CAJ19276.1| putative epoxide hydrolase [Solanum commers... 348 6e-94
ref|YP_001683228.1| alpha/beta hydrolase fold [Caulobacter ... 348 6e-94
dbj|BAC11230.1| unnamed protein product [Homo sapiens] 348 7e-94
ref|NP_775838.2| abhydrolase domain containing 7 [Homo sapi... 348 8e-94
pdb|2CJP|A Chain A, Structure Of Potato (Solanum Tuberosum)... 347 1e-93
gb|AAA81892.1| epoxide hydrolase 347 1e-93
ref|YP_761108.1| putative epoxide hydrolase [Hyphomonas nep... 347 2e-93
ref|XP_694838.2| PREDICTED: hypothetical protein [Danio rerio] 347 2e-93
ref|XP_001377064.1| PREDICTED: similar to abhydrolase domai... 346 2e-93
ref|YP_890327.1| epoxide hydrolase [Mycobacterium smegmatis... 346 3e-93
ref|ZP_00877473.1| COG0596: Predicted hydrolases or acyltra... 346 3e-93
ref|ZP_00108314.1| COG0596: Predicted hydrolases or acyltra... 346 3e-93
ref|YP_703564.1| probable epoxide hydrolase [Rhodococcus sp... 346 3e-93
ref|YP_586462.1| alpha/beta hydrolase fold [Ralstonia metal... 345 4e-93
ref|NP_001067364.1| Os12g0636400 [Oryza sativa (japonica cu... 345 5e-93
gb|AAA81889.1| epoxide hydrolase 345 8e-93
ref|YP_001545639.1| alpha/beta hydrolase fold [Herpetosipho... 344 1e-92
ref|YP_001890397.1| alpha/beta hydrolase fold [Burkholderia... 344 1e-92
ref|YP_002767073.1| epoxide hydrolase [Rhodococcus erythrop... 344 1e-92
sp|Q6IE26|ABHD7_MOUSE Abhydrolase domain-containing protein... 343 2e-92
ref|NP_354796.1| epoxide hydrolase [Agrobacterium tumefacie... 343 2e-92
gb|EAY73347.1| hypothetical protein OsI_001194 [Oryza sativ... 343 3e-92
ref|NP_001001804.2| epoxide hydrolase-related [Mus musculus... 342 3e-92
ref|YP_001132685.1| alpha/beta hydrolase fold [Mycobacteriu... 342 4e-92
gb|EDL20166.1| abhydrolase domain containing 7 [Mus musculus] 342 4e-92
ref|NP_488261.1| hypothetical protein all4221 [Nostoc sp. P... 342 5e-92
gb|ACO95125.1| epoxide hydrolase [uncultured organism] 342 5e-92
ref|XP_001475646.1| PREDICTED: similar to epoxide hydrolase... 342 6e-92
ref|ZP_01728131.1| Alpha/beta hydrolase fold protein [Cyano... 342 7e-92
ref|NP_356953.2| epoxide hydrolase [Agrobacterium tumefacie... 341 8e-92
ref|YP_001073412.1| alpha/beta hydrolase fold [Mycobacteriu... 341 9e-92
ref|YP_641931.1| alpha/beta hydrolase fold [Mycobacterium s... 341 1e-91
ref|XP_422345.2| PREDICTED: similar to Abhydrolase domain c... 341 1e-91
gb|AAA81891.1| epoxide hydrolase 341 1e-91
ref|YP_568956.1| alpha/beta hydrolase fold [Rhodopseudomona... 340 1e-91
ref|ZP_02976857.1| alpha/beta hydrolase fold [Cyanothece sp... 340 1e-91
ref|ZP_01621577.1| hypothetical protein L8106_23540 [Lyngby... 340 1e-91
ref|YP_001614793.1| putative hydrolase of unknown specifici... 340 2e-91
ref|ZP_02940345.1| alpha/beta hydrolase fold [Cyanothece sp... 340 2e-91
ref|NP_001055069.1| Os05g0273800 [Oryza sativa (japonica cu... 339 4e-91
ref|YP_260055.1| ephA [Pseudomonas fluorescens Pf-5] >gi|68... 339 4e-91
ref|YP_001828370.1| putative epoxide hydrolase [Streptomyce... 339 5e-91
emb|CAG05638.1| unnamed protein product [Tetraodon nigrovir... 339 5e-91
ref|YP_002769440.1| epoxide hydrolase [Rhodococcus erythrop... 339 5e-91
ref|ZP_01615162.1| EphA [marine gamma proteobacterium HTCC2... 339 5e-91
ref|YP_001515531.1| hydrolase, alpha/beta fold family [Acar... 339 5e-91
gb|EAY92419.1| hypothetical protein OsI_013652 [Oryza sativ... 338 7e-91
ref|YP_531536.1| alpha/beta hydrolase fold [Rhodopseudomona... 338 7e-91
ref|ZP_01629817.1| Alpha/beta hydrolase fold protein [Nodul... 337 1e-90
ref|YP_002780595.1| epoxide hydrolase [Rhodococcus opacus B... 337 2e-90
ref|YP_956150.1| alpha/beta hydrolase fold [Mycobacterium v... 336 2e-90
ref|NP_627771.1| epoxide hydrolase [Streptomyces coelicolor... 335 4e-90
ref|NP_866425.1| probable ephA protein-Mycobacterium tuberc... 335 5e-90
ref|NP_769521.1| epoxide hydrolase [Bradyrhizobium japonicu... 334 1e-89
ref|NP_823281.1| epoxide hydrolase [Streptomyces avermitili... 334 1e-89
ref|ZP_01690851.1| epoxide hydrolase 2 [Microscilla marina ... 333 2e-89
ref|YP_476608.1| hydrolase, alpha/beta fold family [Synecho... 333 2e-89
gb|AAA81893.1| epoxide hydrolase 332 3e-89
ref|ZP_03874491.1| predicted hydrolase or acyltransferase o... 332 4e-89
ref|XP_547281.2| PREDICTED: similar to abhydrolase domain c... 332 4e-89
ref|NP_193331.3| epoxide hydrolase, putative [Arabidopsis t... 332 7e-89
ref|YP_001828469.1| putative epoxide hydrolase [Streptomyce... 331 9e-89
ref|ZP_01717897.1| probable ephA protein-Mycobacterium tube... 329 3e-88
ref|ZP_01864318.1| putative epoxide hydrolase [Erythrobacte... 329 6e-88
ref|YP_001704492.1| Probable epoxide hydrolase EphA [Mycoba... 327 1e-87
gb|ABK24656.1| unknown [Picea sitchensis] 326 3e-87
ref|YP_473962.1| hydrolase, alpha/beta fold family [Synecho... 326 3e-87
ref|NP_180242.1| ATSEH (Arabidopsis thaliana soluble epoxid... 325 5e-87
ref|YP_954785.1| alpha/beta hydrolase fold [Mycobacterium v... 324 1e-86
ref|YP_001543763.1| alpha/beta hydrolase fold [Herpetosipho... 324 2e-86
ref|XP_001261159.1| epoxide hydrolase [Neosartorya fischeri... 322 4e-86
ref|XP_001275970.1| epoxide hydrolase [Aspergillus clavatus... 322 4e-86
ref|ZP_01115718.1| probable ephA protein-Mycobacterium tube... 322 5e-86
ref|YP_611899.1| alpha/beta hydrolase fold [Silicibacter sp... 322 5e-86
ref|YP_001519646.1| alpha/beta hydrolase fold [Acaryochlori... 322 5e-86
ref|YP_444434.1| hydrolase, alpha/beta fold family, putativ... 322 5e-86
ref|YP_137702.1| epoxide hydrolase-related protein [Haloarc... 322 7e-86
ref|XP_001493089.1| PREDICTED: similar to abhydrolase domai... 320 2e-85
ref|NP_388739.1| hypothetical protein BSU08590 [Bacillus su... 320 2e-85
ref|YP_174259.1| hypothetical protein ABC0759 [Bacillus cla... 319 3e-85
ref|YP_001277175.1| alpha/beta hydrolase fold [Roseiflexus ... 319 3e-85
ref|YP_001859441.1| alpha/beta hydrolase fold protein [Burk... 319 4e-85
ref|ZP_02185384.1| hypothetical protein CAT7_04257 [Carnoba... 318 6e-85
ref|YP_001851161.1| epoxide hydrolase EphB [Mycobacterium m... 318 8e-85
ref|XP_001179361.1| PREDICTED: similar to soluble epoxide h... 318 1e-84
ref|ZP_01617969.1| putative epoxide hydrolase [marine gamma... 317 1e-84
ref|YP_954781.1| alpha/beta hydrolase fold [Mycobacterium v... 316 2e-84
ref|NP_681708.1| putative hydrolase [Thermosynechococcus el... 316 3e-84
gb|ABL97724.1| epoxide hydrolase [uncultured marine bacteri... 316 4e-84
ref|ZP_01039937.1| Alpha/beta hydrolase fold protein [Eryth... 315 7e-84
ref|ZP_02119758.1| hydrolase, alpha/beta fold family, putat... 314 1e-83
ref|NP_001072430.1| hydrolase (3B446) [Xenopus tropicalis] ... 314 1e-83
ref|YP_001432538.1| alpha/beta hydrolase fold [Roseiflexus ... 314 2e-83
emb|CAB46034.1| putative epoxide hydrolase [Arabidopsis tha... 313 2e-83
ref|YP_002785957.1| putative hydrolase, alpha/beta fold fam... 313 3e-83
ref|XP_001402257.1| hypothetical protein An04g09000 [Asperg... 312 5e-83
pdb|2E3J|A Chain A, The Crystal Structure Of Epoxide Hydrol... 312 5e-83
pdb|2ZJF|A Chain A, Crystal Structure Of Mycobacterium Tube... 312 5e-83
ref|YP_722358.1| alpha/beta hydrolase fold [Trichodesmium e... 312 5e-83
ref|NP_216454.1| PROBABLE EPOXIDE HYDROLASE EPHB (EPOXIDE H... 312 5e-83
ref|NP_497268.1| K02F3.6 [Caenorhabditis elegans] >gi|15375... 312 6e-83
gb|EEH35520.1| epoxide hydrolase [Paracoccidioides brasilie... 310 2e-82
ref|ZP_01014743.1| putative epoxide hydrolase [Rhodobactera... 310 2e-82
ref|YP_483368.1| alpha/beta hydrolase fold [Frankia sp. CcI... 310 2e-82
ref|NP_927205.1| similar to epoxide hydrolase [Gloeobacter ... 310 3e-82
ref|YP_001753313.1| alpha/beta hydrolase fold [Methylobacte... 309 3e-82
ref|NP_001099464.1| abhydrolase domain containing 7 [Rattus... 309 3e-82
ref|YP_758097.1| alpha/beta hydrolase fold [Maricaulis mari... 309 4e-82
ref|YP_001641284.1| alpha/beta hydrolase fold [Methylobacte... 309 4e-82
ref|YP_906638.1| epoxide hydrolase EphB [Mycobacterium ulce... 308 5e-82
ref|YP_001485500.1| possible alpha/beta family hydrolase [B... 308 6e-82
ref|YP_001926939.1| alpha/beta hydrolase fold [Methylobacte... 308 7e-82
ref|YP_716691.1| putative hydrolase [Frankia alni ACN14a] >... 308 8e-82
ref|NP_180243.1| epoxide hydrolase, putative [Arabidopsis t... 308 9e-82
ref|NP_296269.1| epoxide hydrolase-related protein [Deinoco... 307 1e-81
ref|YP_001614132.1| Epoxide hydrolase [Sorangium cellulosum... 307 1e-81
ref|NP_001064967.1| Os10g0498300 [Oryza sativa (japonica cu... 307 1e-81
ref|YP_001420483.1| YfhM [Bacillus amyloliquefaciens FZB42]... 307 1e-81
gb|ABL97491.1| putative epoxide hydrolase [uncultured marin... 306 2e-81
ref|XP_699161.2| PREDICTED: hypothetical protein [Danio rerio] 306 4e-81
gb|EEH44735.1| epoxide hydrolase [Paracoccidioides brasilie... 306 4e-81
ref|XP_512451.2| PREDICTED: abhydrolase domain containing 9... 305 5e-81
ref|YP_001771224.1| alpha/beta hydrolase fold [Methylobacte... 305 7e-81
ref|XP_796464.1| PREDICTED: hypothetical protein [Strongylo... 305 7e-81
ref|ZP_01623368.1| epoxide hydrolase-like protein [Lyngbya ... 305 8e-81
ref|NP_079070.1| abhydrolase domain containing 9 [Homo sapi... 304 1e-80
ref|ZP_03999388.1| predicted hydrolase or acyltransferase o... 304 1e-80
gb|EAZ29152.1| hypothetical protein OsJ_012635 [Oryza sativ... 303 2e-80
ref|YP_343030.1| Alpha/beta hydrolase fold [Nitrosococcus o... 303 2e-80
ref|YP_001189322.1| alpha/beta hydrolase fold [Pseudomonas ... 303 2e-80
ref|XP_001239812.1| hypothetical protein CIMG_09433 [Coccid... 302 4e-80
ref|YP_458350.1| possible epoxide hydrolase-related protein... 301 9e-80
ref|NP_001064968.1| Os10g0498500 [Oryza sativa (japonica cu... 301 1e-79
ref|YP_001682147.1| alpha/beta hydrolase fold [Caulobacter ... 301 1e-79
gb|EDL40330.1| mCG14254 [Mus musculus] 300 1e-79
gb|AAI45798.1| Abhd9 protein [Mus musculus] 300 2e-79
emb|CAN65368.1| hypothetical protein [Vitis vinifera] 300 2e-79
ref|NP_001064966.1| Os10g0498200 [Oryza sativa (japonica cu... 300 3e-79
gb|EAY79083.1| hypothetical protein OsI_033042 [Oryza sativ... 299 4e-79
emb|CAO16924.1| unnamed protein product [Vitis vinifera] 299 5e-79
ref|ZP_01615341.1| Alpha/beta hydrolase fold protein [marin... 298 7e-79
ref|NP_001028335.1| abhydrolase domain containing 9 [Mus mu... 298 9e-79
sp|Q3V1F8|ABHD9_MOUSE Abhydrolase domain-containing protein... 296 3e-78
ref|YP_002763933.1| hydrolase [Rhodococcus erythropolis PR4... 295 5e-78
ref|YP_569809.1| alpha/beta hydrolase fold [Rhodopseudomona... 295 6e-78
ref|YP_001637560.1| alpha/beta hydrolase fold [Methylobacte... 295 6e-78
ref|XP_001651935.1| epoxide hydrolase [Aedes aegypti] >gi|1... 295 7e-78
ref|XP_588758.3| PREDICTED: similar to ACAD 10 [Bos taurus] 295 7e-78
emb|CAD31713.1| epoxide hydrolase [Cicer arietinum] 295 8e-78
gb|EAW97961.1| acyl-Coenzyme A dehydrogenase family, member... 295 8e-78
gb|EAW97967.1| acyl-Coenzyme A dehydrogenase family, member... 295 8e-78
ref|ZP_02118668.1| hydrolase, alpha/beta fold family, putat... 295 8e-78
ref|YP_001899009.1| alpha/beta hydrolase fold [Ralstonia pi... 295 9e-78
gb|EAW97968.1| acyl-Coenzyme A dehydrogenase family, member... 295 9e-78
ref|XP_001108979.1| PREDICTED: similar to acyl-Coenzyme A d... 294 1e-77
gb|EEJ95824.1| predicted hydrolase or acyltransferase of al... 294 1e-77
ref|XP_001674008.1| Hypothetical protein CBG09592 [Caenorha... 294 1e-77
ref|XP_001109036.1| PREDICTED: similar to acyl-Coenzyme A d... 294 1e-77
ref|XP_001367122.1| PREDICTED: hypothetical protein [Monode... 294 2e-77
ref|ZP_03892255.1| predicted hydrolase or acyltransferase o... 293 2e-77
ref|NP_519891.1| PROBABLE HYDROLASE PROTEIN [Ralstonia sola... 293 2e-77
gb|EAY79085.1| hypothetical protein OsI_033044 [Oryza sativ... 293 2e-77
ref|ZP_02016666.1| alpha/beta hydrolase fold [Halorubrum la... 293 2e-77
ref|XP_001146527.1| PREDICTED: hypothetical protein isoform... 293 3e-77
ref|XP_001217680.1| predicted protein [Aspergillus terreus ... 293 3e-77
ref|ZP_02299274.1| alpha/beta hydrolase fold [Rhodopseudomo... 293 3e-77
gb|EAW97971.1| acyl-Coenzyme A dehydrogenase family, member... 293 3e-77
ref|YP_781734.1| alpha/beta hydrolase fold [Rhodopseudomona... 292 4e-77
ref|YP_002781429.1| putative hydrolase [Rhodococcus opacus ... 292 4e-77
ref|XP_509377.2| PREDICTED: acyl-Coenzyme A dehydrogenase f... 292 4e-77
ref|NP_001102458.1| abhydrolase domain containing 9 [Rattus... 292 4e-77
gb|AAB02006.1| epoxide hydrolase [Nicotiana tabacum] 292 4e-77
ref|NP_948077.1| possible epoxide hydrolase-related protein... 292 4e-77
gb|EAW63550.1| epoxide hydrolase 2, cytoplasmic, isoform CR... 292 5e-77
ref|XP_001146445.1| PREDICTED: acyl-Coenzyme A dehydrogenas... 292 5e-77
ref|XP_875305.1| PREDICTED: hypothetical protein [Bos taurus] 292 5e-77
ref|YP_288193.1| putative hydrolase [Thermobifida fusca YX]... 292 5e-77
ref|XP_001803986.1| hypothetical protein SNOG_13782 [Phaeos... 292 6e-77
ref|XP_320560.3| AGAP011972-PA [Anopheles gambiae str. PEST... 292 6e-77
ref|XP_001109257.1| PREDICTED: similar to acyl-Coenzyme A d... 292 6e-77
ref|XP_001146998.1| PREDICTED: acyl-Coenzyme A dehydrogenas... 292 6e-77
ref|ZP_02055448.1| alpha/beta hydrolase fold [Methylobacter... 292 6e-77
ref|YP_001234160.1| alpha/beta hydrolase fold [Acidiphilium... 292 8e-77
gb|EAW97963.1| acyl-Coenzyme A dehydrogenase family, member... 292 8e-77
ref|YP_486258.1| Alpha/beta hydrolase [Rhodopseudomonas pal... 291 1e-76
ref|ZP_04000668.1| predicted hydrolase or acyltransferase o... 291 1e-76
ref|NP_505662.1| K07C5.5 [Caenorhabditis elegans] >gi|38783... 291 1e-76
ref|XP_001147201.1| PREDICTED: acyl-Coenzyme A dehydrogenas... 291 1e-76
ref|YP_583993.1| alpha/beta hydrolase fold [Ralstonia metal... 291 1e-76
Sequences not found previously or not previously below threshold:
>ref|XP_001163779.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 3 [Pan
troglodytes]
ref|XP_001163923.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 7 [Pan
troglodytes]
ref|XP_519676.2| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 8 [Pan
troglodytes]
Length = 555
Score = 843 bits (2178), Expect = 0.0, Method: Composition-based stats.
Identities = 549/555 (98%), Positives = 554/555 (99%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG+SS
Sbjct: 241 YVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGKSS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>ref|NP_001970.2| epoxide hydrolase 2, cytoplasmic [Homo sapiens]
sp|P34913|HYES_HUMAN Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
pdb|1S8O|A Chain A, Human Soluble Epoxide Hydrolase
pdb|1VJ5|A Chain A, Human Soluble Epoxide Hydrolase- N-Cyclohexyl-N'-(4-
Iodophenyl)urea Complex
pdb|1ZD2|P Chain P, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Ethanoic Acid Complex
pdb|1ZD3|A Chain A, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Butyric Acid Complex
pdb|1ZD4|A Chain A, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Hexanoic Acid Complex
pdb|1ZD5|A Chain A, Human Soluble Epoxide Hydrolase 4-(3-Cyclohexyluriedo)-
Heptanoic Acid Complex
gb|AAG14966.1|AF233334_1 soluble epoxide hydrolase [Homo sapiens]
emb|CAA65751.1| epoxide hydrolase [Homo sapiens]
gb|AAH07708.1| Epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAH11628.1| Epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAH13874.1| Epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAP35531.1| epoxide hydrolase 2, cytoplasmic [Homo sapiens]
gb|AAX42304.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
gb|AAX42305.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
gb|EAW63548.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_b [Homo sapiens]
gb|ABM83675.1| epoxide hydrolase 2, cytoplasmic [synthetic construct]
gb|ABM86963.1| epoxide hydrolase 2, cytoplasmic [synthetic construct]
gb|ACD11487.1| epoxide hydrolase 2, cytoplasmic [Homo sapiens]
Length = 555
Score = 840 bits (2172), Expect = 0.0, Method: Composition-based stats.
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>gb|AAP36260.1| Homo sapiens epoxide hydrolase 2, cytoplasmic [synthetic construct]
gb|AAX29746.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
gb|AAX29747.1| epoxide hydrolase 2 cytoplasmic [synthetic construct]
Length = 556
Score = 840 bits (2171), Expect = 0.0, Method: Composition-based stats.
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>gb|AAG14967.1|AF233335_1 soluble epoxide hydrolase [Homo sapiens]
Length = 555
Score = 838 bits (2165), Expect = 0.0, Method: Composition-based stats.
Identities = 554/555 (99%), Positives = 555/555 (100%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGY+VLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYQVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 541 WLDSDARNPPVVSKM 555
>gb|AAG14968.1|AF233336_1 soluble epoxide hydrolase [Homo sapiens]
Length = 556
Score = 837 bits (2162), Expect = 0.0, Method: Composition-based stats.
Identities = 554/556 (99%), Positives = 554/556 (99%), Gaps = 1/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNL-SRTFKSLFRASDESVLSM 419
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNL RTFKSLFRASDESVLSM
Sbjct: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRRTFKSLFRASDESVLSM 420
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS
Sbjct: 421 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 480
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI
Sbjct: 481 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 540
Query: 540 KWLDSDARNPPVVSKM 555
KWLDSDARNPPVVSKM
Sbjct: 541 KWLDSDARNPPVVSKM 556
>gb|EAW63547.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Homo sapiens]
Length = 568
Score = 832 bits (2151), Expect = 0.0, Method: Composition-based stats.
Identities = 554/568 (97%), Positives = 554/568 (97%), Gaps = 13/568 (2%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPR-------------GLLNDAFQKGGPE 47
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALP GLLNDAFQKGGPE
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPSSGGWKSKIKMSAGGLLNDAFQKGGPE 60
Query: 48 GATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQ 107
GATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQ
Sbjct: 61 GATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQ 120
Query: 108 AALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYK 167
AALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYK
Sbjct: 121 AALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYK 180
Query: 168 FLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAP 227
FLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAP
Sbjct: 181 FLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAP 240
Query: 228 LPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYR 287
LPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYR
Sbjct: 241 LPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYR 300
Query: 288 VLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALF 347
VLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALF
Sbjct: 301 VLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALF 360
Query: 348 YPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS 407
YPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS
Sbjct: 361 YPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS 420
Query: 408 LFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYR 467
LFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYR
Sbjct: 421 LFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYR 480
Query: 468 NMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ 527
NMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ
Sbjct: 481 NMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ 540
Query: 528 MDKPTEVNQILIKWLDSDARNPPVVSKM 555
MDKPTEVNQILIKWLDSDARNPPVVSKM
Sbjct: 541 MDKPTEVNQILIKWLDSDARNPPVVSKM 568
>ref|XP_001163896.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 6 [Pan
troglodytes]
Length = 560
Score = 828 bits (2140), Expect = 0.0, Method: Composition-based stats.
Identities = 544/560 (97%), Positives = 551/560 (98%), Gaps = 5/560 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQ-----AGYRVLAMDMKG 295
YVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQ+ L + AGYRVLAMDMKG
Sbjct: 241 YVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQVRKLGKMQPVRAGYRVLAMDMKG 300
Query: 296 YGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV 355
YG+SSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV
Sbjct: 301 YGKSSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAV 360
Query: 356 ASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES 415
ASLNTPFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES
Sbjct: 361 ASLNTPFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDES 420
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW
Sbjct: 421 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 480
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 535
ACKSLGRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVN
Sbjct: 481 ACKSLGRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 540
Query: 536 QILIKWLDSDARNPPVVSKM 555
QILIKWLDSDARNPPVVSKM
Sbjct: 541 QILIKWLDSDARNPPVVSKM 560
>gb|AAA02756.1| cytosolic epoxide hydrolase
Length = 554
Score = 828 bits (2139), Expect = 0.0, Method: Composition-based stats.
Identities = 552/555 (99%), Positives = 552/555 (99%), Gaps = 1/555 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLR AVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
Sbjct: 1 MTLRGAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKPRVRLHFVELG PAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
Sbjct: 241 YVTVKPRVRLHFVELG-WPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 299
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 300 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 359
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 360 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 419
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 420 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 479
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 480 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 539
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 540 WLDSDARNPPVVSKM 554
>ref|XP_001109474.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic [Macaca
mulatta]
Length = 556
Score = 817 bits (2110), Expect = 0.0, Method: Composition-based stats.
Identities = 519/556 (93%), Positives = 538/556 (96%), Gaps = 1/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAF KGGPEGATTRLM+GEITL
Sbjct: 1 MALRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFHKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCS+T++V LPKNFS+ EIF KAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSQTSEVSLPKNFSVNEIFGKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELK HFDFLIESCQVGMVKPEPQIY+FLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKTHFDFLIESCQVGMVKPEPQIYRFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD+G+NLKPARDLGMVTILVQDTDTAL+ELEKVTGIQLLNTPAPLPT CNPSD+SHG
Sbjct: 181 VFLDDVGSNLKPARDLGMVTILVQDTDTALRELEKVTGIQLLNTPAPLPTCCNPSDVSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVT+KP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRV+AMDMKGYGESS
Sbjct: 241 YVTIKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVIAMDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMV-TFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
APPEIEEYCMEVLCKE V +LGLSQAVFIGHDWGG+LVWYMALFYPERVRAVASLN
Sbjct: 301 APPEIEEYCMEVLCKETVPRLAGELGLSQAVFIGHDWGGVLVWYMALFYPERVRAVASLN 360
Query: 360 TPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSM 419
TPFIPANPN+ PLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSM
Sbjct: 361 TPFIPANPNVPPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSM 420
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HKVCE GGLFV +PEEPSLSRMV+EEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS
Sbjct: 421 HKVCEMGGLFVRTPEEPSLSRMVSEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 480
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKP EVNQILI
Sbjct: 481 LGRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPAEVNQILI 540
Query: 540 KWLDSDARNPPVVSKM 555
KWL+SDARNPPVVSKM
Sbjct: 541 KWLESDARNPPVVSKM 556
>ref|NP_001069002.1| epoxide hydrolase 2, cytoplasmic [Bos taurus]
gb|AAI18307.1| Epoxide hydrolase 2, cytoplasmic [Bos taurus]
Length = 555
Score = 809 bits (2090), Expect = 0.0, Method: Composition-based stats.
Identities = 415/555 (74%), Positives = 488/555 (87%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVF+L G+L LP+ R EE LALP G L+ AF +GGP+G + R+MKGEIT
Sbjct: 1 MALRAAVFELGGILTLPSATSFWDRAEEELALPGGFLSKAFLRGGPDGPSIRVMKGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+P MEE+CRKCS+ +CLP+NFSIK+IF+K +S+RKIN PMLQAA+ L++KGFTT
Sbjct: 61 SQWVPFMEEDCRKCSKDCGICLPENFSIKQIFEKILSSRKINYPMLQAAVTLKQKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDD AER LAQ++CELK HFDFLIESCQ+GMVKP+PQIYKF+LDTLK SPSEV
Sbjct: 121 ILTNTWLDDSAERGSLAQVLCELKPHFDFLIESCQIGMVKPDPQIYKFVLDTLKISPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLD+ NLKPA ++GMVTI V DTD ALKELEKVTG+QLL T AP P SC+PS M+HG
Sbjct: 181 VFLDNFETNLKPAHEMGMVTIFVHDTDAALKELEKVTGVQLLQTSAPQPISCDPSTMTHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLHFVELGSGP VCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHFVELGSGPVVCLCHGFPESWFSWRYQIPALAQAGFRVLAVDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY +EVL K+M+TFLDKLG+SQAVFIGHDWGGMLVW +ALF+PERVRAVASLNT
Sbjct: 301 APPEIEEYSLEVLSKDMITFLDKLGISQAVFIGHDWGGMLVWTIALFHPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+P+NP +S +E IKA P F+YQLYFQEPGVAEAELE+NLSRTFKS FR++DE+ +++
Sbjct: 361 PFMPSNPKVSTMEIIKATPTFNYQLYFQEPGVAEAELEKNLSRTFKSFFRSNDETFITVS 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+ CE GGL VN+PEEP+LS+MVTEE+IQFYVQ+FKKSGFRGPLNWYRNM++NW+W K
Sbjct: 421 RTCEMGGLLVNTPEEPTLSKMVTEEDIQFYVQEFKKSGFRGPLNWYRNMDKNWEWGFKGS 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKD VL P+MS+HMEDWIPHLKRGHI+DCGHWTQM+KPTE+N+ILI+
Sbjct: 481 GRKILIPALMVTAEKDLVLTPEMSKHMEDWIPHLKRGHIKDCGHWTQMEKPTELNRILIE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DAR+ PVVSK+
Sbjct: 541 WLETDARDLPVVSKL 555
>ref|NP_001001641.1| soluble epoxide hydrolase [Sus scrofa]
sp|Q6Q2C2|HYES_PIG Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
gb|AAS68016.1| soluble epoxide hydrolase [Sus scrofa]
Length = 555
Score = 796 bits (2057), Expect = 0.0, Method: Composition-based stats.
Identities = 430/555 (77%), Positives = 494/555 (89%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP++ R EE LALPRG LN+AF+KGG +G+ R+M GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSITTSWARAEEKLALPRGFLNEAFKKGGQDGSVARVMTGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+P MEE+CRKC+E + + LP+NFS+K IFDKA+S +KIN PMLQAAL L+KKGF+T
Sbjct: 61 SQWVPFMEEDCRKCAEDSGIRLPENFSVKHIFDKALSEKKINYPMLQAALTLKKKGFSTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD A+R AQLMCEL+ HFDFLIESC+VGM KP+PQIYK +LDTLKA P+EV
Sbjct: 121 ILTNNWLDDSAQRGSRAQLMCELRPHFDFLIESCRVGMAKPDPQIYKLMLDTLKAEPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD+G +LKP RDLGM TILV+DTDTAL+ELEKVTG+QLL TPA PTSC+PS +SHG
Sbjct: 181 VFLDDVGTHLKPVRDLGMATILVRDTDTALRELEKVTGVQLLQTPALPPTSCDPSALSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLHFVE+GSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVLIKPGVRLHFVEMGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLAVDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY +EVLCK+MVTFL+KLGLSQAVFIGHDWGG+LVW MALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYSLEVLCKDMVTFLNKLGLSQAVFIGHDWGGVLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+P+NPN+SP+E IKANPVFDYQLYFQEPGVAEAELEQNL RTFK+ FRA DE+ L+ +
Sbjct: 361 PFMPSNPNVSPMEIIKANPVFDYQLYFQEPGVAEAELEQNLDRTFKNFFRAHDETFLTTN 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+V E GGLFV +PEEPSLSR+VTEE+IQFYVQQFKKSGFRGPLNWYRNMERNW+W CK
Sbjct: 421 RVRELGGLFVGTPEEPSLSRLVTEEDIQFYVQQFKKSGFRGPLNWYRNMERNWQWGCKGS 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAE D VL P+MS+HME+WIPHLKRGHI+DCGHWTQ+DKP E+N+ILI+
Sbjct: 481 GRKILIPALMVTAENDLVLHPKMSKHMENWIPHLKRGHIKDCGHWTQIDKPAELNRILIE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DARNP V SK+
Sbjct: 541 WLETDARNPLVDSKL 555
>ref|XP_001492725.1| PREDICTED: similar to soluble epoxide hydrolase [Equus caballus]
Length = 555
Score = 792 bits (2045), Expect = 0.0, Method: Composition-based stats.
Identities = 437/555 (78%), Positives = 495/555 (89%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP++ GR EE LALPRG L++A GP+ + RL+ GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSIARAFGRAEEDLALPRGFLSEALNLKGPDESIARLVTGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+P ++E+C+K S+ + + LP+ FSI +IF KAISARKIN PMLQAAL LRKKGFTT
Sbjct: 61 SQWVPFIDEDCKKRSKNSGINLPEEFSINQIFAKAISARKINHPMLQAALTLRKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD +ER LAQL+CEL+ HFDFLIESC++ M KPEPQIYK++LDTLKASP+EV
Sbjct: 121 ILTNNWLDDSSERGTLAQLLCELRPHFDFLIESCRIRMAKPEPQIYKYVLDTLKASPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGA LKPARDLGMVTILV+DTDTAL+ELEKVTG+QLL T APLPT C+P+D+SHG
Sbjct: 181 VFLDDIGAYLKPARDLGMVTILVRDTDTALRELEKVTGMQLLKTAAPLPTPCSPNDVSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLHFVELG GPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHFVELGCGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLAVDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY MEVLCK+MVTFLDKLG+SQAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYSMEVLCKDMVTFLDKLGISQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+PANPN+SP+E IKANPVF+YQLYFQEPGVAEAELEQNLSRTFKS FR SDE LS
Sbjct: 361 PFMPANPNVSPMEIIKANPVFNYQLYFQEPGVAEAELEQNLSRTFKSFFRTSDEGFLSTS 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+VCE GGLFV +PEEPSLS MV+EE+IQFYVQQF+KSGFRGPLNWYRN+ERNW+W CK
Sbjct: 421 RVCERGGLFVAAPEEPSLSSMVSEEDIQFYVQQFRKSGFRGPLNWYRNVERNWQWGCKGS 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKD VLVP+MS+HMEDWIPHLKRGHI+DCGHWTQM+KPTE+NQIL +
Sbjct: 481 GRKILIPALMVTAEKDVVLVPEMSKHMEDWIPHLKRGHIKDCGHWTQMEKPTELNQILTE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DAR+P VVSK+
Sbjct: 541 WLETDARDPLVVSKL 555
>ref|XP_534566.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 1
[Canis familiaris]
Length = 556
Score = 791 bits (2044), Expect = 0.0, Method: Composition-based stats.
Identities = 436/556 (78%), Positives = 496/556 (89%), Gaps = 1/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+QLL T A LP CNPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQLLQTAAALPVPCNPSDMSHV 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 301 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESV-LSM 419
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD L++
Sbjct: 361 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKPFLNV 420
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+V E GGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W CK
Sbjct: 421 GRVRERGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGCKG 480
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
+GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQILI
Sbjct: 481 VGRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQILI 540
Query: 540 KWLDSDARNPPVVSKM 555
+WL++DAR+PPVVSK+
Sbjct: 541 EWLETDARDPPVVSKL 556
>ref|XP_857471.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 3
[Canis familiaris]
Length = 555
Score = 790 bits (2042), Expect = 0.0, Method: Composition-based stats.
Identities = 435/555 (78%), Positives = 493/555 (88%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+QLL T A LP CNPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQLLQTAAALPVPCNPSDMSHV 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 241 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 301 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD V
Sbjct: 361 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKVSVAE 420
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
+ AGGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W CK +
Sbjct: 421 RWLFAGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGCKGV 480
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQILI+
Sbjct: 481 GRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQILIE 540
Query: 541 WLDSDARNPPVVSKM 555
WL++DAR+PPVVSK+
Sbjct: 541 WLETDARDPPVVSKL 555
>ref|XP_857554.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 4
[Canis familiaris]
Length = 554
Score = 788 bits (2037), Expect = 0.0, Method: Composition-based stats.
Identities = 431/556 (77%), Positives = 493/556 (88%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+Q + P+P NPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQSPKSALPVPC--NPSDMSHV 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 239 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESV-LSM 419
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD L++
Sbjct: 359 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKPFLNV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+V E GGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W CK
Sbjct: 419 GRVRERGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
+GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQILI
Sbjct: 479 VGRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
+WL++DAR+PPVVSK+
Sbjct: 539 EWLETDARDPPVVSKL 554
>ref|XP_857430.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic isoform 2
[Canis familiaris]
Length = 556
Score = 787 bits (2034), Expect = 0.0, Method: Composition-based stats.
Identities = 428/558 (76%), Positives = 488/558 (87%), Gaps = 5/558 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAAVFDLDGVLALP+V G L RTE LALPRG LN+A Q GGP+G++ RLM+GEIT
Sbjct: 1 MALRAAVFDLDGVLALPSVVGALRRTEAELALPRGFLNEASQTGGPDGSSARLMRGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE CRKC+E + +CLP+NFS+ +IF +A +ARKIN PMLQAAL LRKKG+TT
Sbjct: 61 SQWVPLMEEGCRKCAEVSGICLPENFSVSQIFGRAAAARKINHPMLQAALALRKKGYTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD ++R LAQL+C+L HF+F+IESC++ M KP+PQIYKF+LDTLKASPSEV
Sbjct: 121 ILTNNWLDDSSQRGSLAQLVCQLSPHFNFVIESCRISMAKPDPQIYKFVLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGM TILV+DTD AL EL+KVTG+Q + P+P NPSDMSH
Sbjct: 181 VFLDDIGANLKPARDLGMATILVRDTDPALTELQKVTGVQSPKSALPVPC--NPSDMSHV 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV +KP VRLH VELGSGPAVCLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYGESS
Sbjct: 239 YVPIKPGVRLHCVELGSGPAVCLCHGFPESWFSWRYQIPALAQAGFRVLALDMKGYGESS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY MEVLC+EMVTFLDKLG+ QAVFIGHDWGGMLVW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYSMEVLCQEMVTFLDKLGIPQAVFIGHDWGGMLVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVL--- 417
PF+PANPN+S +E IKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS FRASD
Sbjct: 359 PFVPANPNVSTMEKIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSFFRASDGKGFETC 418
Query: 418 SMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWAC 477
+ GGL V +PEEPSLS +VTEE+IQFYVQQF+KSGFRGPLNWYRN+E NW+W C
Sbjct: 419 ANRPATAVGGLLVKTPEEPSLSSIVTEEDIQFYVQQFQKSGFRGPLNWYRNVETNWRWGC 478
Query: 478 KSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQI 537
K +GRKILIPALMVTAEKD VLVP+MS+HMEDWIP+LKRGHI+DCGHWTQM+KPTE+NQI
Sbjct: 479 KGVGRKILIPALMVTAEKDKVLVPEMSKHMEDWIPYLKRGHIKDCGHWTQMEKPTELNQI 538
Query: 538 LIKWLDSDARNPPVVSKM 555
LI+WL++DAR+PPVVSK+
Sbjct: 539 LIEWLETDARDPPVVSKL 556
>gb|AAH85732.1| Epoxide hydrolase 2, cytoplasmic [Rattus norvegicus]
gb|EDL85376.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Rattus norvegicus]
Length = 554
Score = 778 bits (2011), Expect = 0.0, Method: Composition-based stats.
Identities = 403/556 (72%), Positives = 477/556 (85%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ GVL TEEALALPR L AFQ PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+CRK S+ LP+NFSI EIF +A++AR INRPMLQAA L+KKGFTT
Sbjct: 61 SQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIYKF+LDTLKA P+EV
Sbjct: 121 IITNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV+DT +AL+ELEKVTG Q P P+P S N D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFPEAPLPVPCSPN--DVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP + LHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGICLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LC+EMVTFL+KLG+ QAVFIGHDW G+LVW MALF+PERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMALFHPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
P +P NP +SP+E I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FR SD+ +L++
Sbjct: 359 PLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+K E GG+ V +PE+P +S++ TEEEI++Y+QQFKKSGFRGPLNWYRN ERNWKW CK+
Sbjct: 419 NKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLNWYRNTERNWKWNCKA 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME+WIP LKRGHIEDCGHWTQ++KP EVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGHWTQIEKPAEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLKTEIQNPSVTSKI 554
>ref|NP_075225.1| epoxide hydrolase 2, cytoplasmic [Rattus norvegicus]
sp|P80299|HYES_RAT Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
emb|CAA46211.1| epoxide hydrolase [Rattus norvegicus]
Length = 554
Score = 778 bits (2010), Expect = 0.0, Method: Composition-based stats.
Identities = 404/556 (72%), Positives = 479/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ GVL TEEALALPR L AFQ PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+CRK S+ LP+NFSI EIF +A++AR INRPMLQAA L+KKGFTT
Sbjct: 61 SQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIYKF+LDTLKA P+EV
Sbjct: 121 IVTNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV+DT +AL+ELEKVTG Q P P+P S N D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFPEAPLPVPCSPN--DVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LC+EMVTFL+KLG+ QAVFIGHDW G+LVW MALF+PERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMALFHPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
P +P NP +SP+E I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FR SD+ +L++
Sbjct: 359 PLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
+K E GG+ V +PE+P +S++ TEEEI++Y+QQFKKSGFRGPLNWYRN ERNWKW+CK+
Sbjct: 419 NKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLNWYRNTERNWKWSCKA 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME+WIP LKRGHIEDCGHWTQ++KP EVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGHWTQIEKPAEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLKTEIQNPSVTSKI 554
>emb|CAA85471.1| Epoxide Hydrolase [Mus musculus]
Length = 554
Score = 775 bits (2002), Expect = 0.0, Method: Composition-based stats.
Identities = 405/556 (72%), Positives = 481/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ G R+EEALALPR L A+Q PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+ RK S+T LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT
Sbjct: 61 SQWVPLMDESYRKSSKTCGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P+EV
Sbjct: 121 IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P NP+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPC--NPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
PF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE +++
Sbjct: 359 PFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK
Sbjct: 419 HKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLQTEVQNPSVTSKI 554
>ref|NP_031966.2| epoxide hydrolase 2, cytoplasmic [Mus musculus]
sp|P34914|HYES_MOUSE Epoxide hydrolase 2 (Soluble epoxide hydrolase) (SEH) (Epoxide
hydratase) (Cytosolic epoxide hydrolase) (CEH)
pdb|1CQZ|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase.
pdb|1CQZ|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase.
pdb|1CR6|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cpu Inhibitor
pdb|1CR6|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cpu Inhibitor
pdb|1EK1|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Ciu Inhibitor
pdb|1EK1|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Ciu Inhibitor
pdb|1EK2|A Chain A, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cdu Inhibitor
pdb|1EK2|B Chain B, Crystal Structure Of Murine Soluble Epoxide Hydrolase
Complexed With Cdu Inhibitor
gb|AAA37555.1| epoxide hydrolase
gb|AAH15087.1| Epoxide hydrolase 2, cytoplasmic [Mus musculus]
gb|EDL36005.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_a [Mus musculus]
Length = 554
Score = 774 bits (2000), Expect = 0.0, Method: Composition-based stats.
Identities = 404/556 (72%), Positives = 480/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ G R+EEALALPR L A+Q PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT
Sbjct: 61 SQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P+EV
Sbjct: 121 IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P NP+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPC--NPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
PF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE +++
Sbjct: 359 PFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK
Sbjct: 419 HKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLQTEVQNPSVTSKI 554
>dbj|BAE25172.1| unnamed protein product [Mus musculus]
Length = 554
Score = 773 bits (1998), Expect = 0.0, Method: Composition-based stats.
Identities = 403/556 (72%), Positives = 480/556 (86%), Gaps = 3/556 (0%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LR A FDLDGVLALP++ G R+EEALALPR L A+Q PEG T +LMKG+IT
Sbjct: 1 MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT
Sbjct: 61 SQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEP+IY FLLDTLKA P+EV
Sbjct: 121 IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPRIYNFLLDTLKAKPNEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P NP+D+SHG
Sbjct: 181 VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPC--NPNDVSHG 238
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS
Sbjct: 239 YVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS 298
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNT
Sbjct: 299 SPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNT 358
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSM 419
PF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE +++
Sbjct: 359 PFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAV 418
Query: 420 HKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKS 479
HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK
Sbjct: 419 HKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKG 478
Query: 480 LGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILI 539
LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILI
Sbjct: 479 LGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILI 538
Query: 540 KWLDSDARNPPVVSKM 555
KWL ++ +NP V SK+
Sbjct: 539 KWLQTEVQNPSVTSKI 554
>ref|XP_001163527.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 1 [Pan
troglodytes]
Length = 502
Score = 773 bits (1996), Expect = 0.0, Method: Composition-based stats.
Identities = 496/502 (98%), Positives = 501/502 (99%)
Query: 54 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 113
M+GEITLSQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLR
Sbjct: 1 MRGEITLSQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLR 60
Query: 114 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 173
KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL
Sbjct: 61 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 120
Query: 174 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 233
KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN
Sbjct: 121 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 180
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
PSDMSHGYVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM
Sbjct: 181 PSDMSHGYVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 240
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
KGYG+SSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR
Sbjct: 241 KGYGKSSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 300
Query: 354 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 413
AVASLNTPFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD
Sbjct: 301 AVASLNTPFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 360
Query: 414 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 473
ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW
Sbjct: 361 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 420
Query: 474 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 533
KWACKSLGRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTE
Sbjct: 421 KWACKSLGRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTE 480
Query: 534 VNQILIKWLDSDARNPPVVSKM 555
VNQILIKWLDSDARNPPVVSKM
Sbjct: 481 VNQILIKWLDSDARNPPVVSKM 502
>gb|EAW63549.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_c [Homo sapiens]
Length = 502
Score = 770 bits (1990), Expect = 0.0, Method: Composition-based stats.
Identities = 502/502 (100%), Positives = 502/502 (100%)
Query: 54 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 113
MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR
Sbjct: 1 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 60
Query: 114 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 173
KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL
Sbjct: 61 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 120
Query: 174 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 233
KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN
Sbjct: 121 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 180
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM
Sbjct: 181 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 240
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR
Sbjct: 241 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 300
Query: 354 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 413
AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD
Sbjct: 301 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 360
Query: 414 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 473
ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW
Sbjct: 361 ESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 420
Query: 474 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 533
KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE
Sbjct: 421 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 480
Query: 534 VNQILIKWLDSDARNPPVVSKM 555
VNQILIKWLDSDARNPPVVSKM
Sbjct: 481 VNQILIKWLDSDARNPPVVSKM 502
>ref|XP_001163861.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 5 [Pan
troglodytes]
Length = 523
Score = 762 bits (1968), Expect = 0.0, Method: Composition-based stats.
Identities = 518/555 (93%), Positives = 523/555 (94%), Gaps = 32/555 (5%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
Sbjct: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVK IPALAQAGYRVLAMDMKGYG+SS
Sbjct: 241 YVTVK--------------------------------IPALAQAGYRVLAMDMKGYGKSS 268
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 269 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 328
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 329 PFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 388
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 389 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 448
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 449 GRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 508
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 509 WLDSDARNPPVVSKM 523
>ref|XP_001163819.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 4 [Pan
troglodytes]
Length = 514
Score = 750 bits (1938), Expect = 0.0, Method: Composition-based stats.
Identities = 506/555 (91%), Positives = 513/555 (92%), Gaps = 41/555 (7%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQWIPLMEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTA
Sbjct: 61 SQWIPLMEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE+
Sbjct: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEL 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
+ NTPAPLPTSCNPSDMSHG
Sbjct: 181 L-----------------------------------------NTPAPLPTSCNPSDMSHG 199
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YVTVKP VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG+SS
Sbjct: 200 YVTVKPGVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGKSS 259
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
Sbjct: 260 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 319
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PFIPANPN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
Sbjct: 320 PFIPANPNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 379
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
Sbjct: 380 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 439
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 540
GRKILIPALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
Sbjct: 440 GRKILIPALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK 499
Query: 541 WLDSDARNPPVVSKM 555
WLDSDARNPPVVSKM
Sbjct: 500 WLDSDARNPPVVSKM 514
>ref|XP_001163565.1| PREDICTED: epoxide hydrolase 2, cytoplasmic isoform 2 [Pan
troglodytes]
Length = 489
Score = 750 bits (1936), Expect = 0.0, Method: Composition-based stats.
Identities = 484/489 (98%), Positives = 488/489 (99%)
Query: 67 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 126
MEENCRKCSETAKVCLPKNFS+KEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW
Sbjct: 1 MEENCRKCSETAKVCLPKNFSVKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 60
Query: 127 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 186
LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI
Sbjct: 61 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 120
Query: 187 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 246
GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP
Sbjct: 121 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 180
Query: 247 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 306
VRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG+SSAPPEIE
Sbjct: 181 GVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGKSSAPPEIE 240
Query: 307 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 366
EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN
Sbjct: 241 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 300
Query: 367 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 426
PN+SPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG
Sbjct: 301 PNVSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 360
Query: 427 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 486
GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI
Sbjct: 361 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 420
Query: 487 PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 546
PALMVTAEKDFVLVPQMS+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA
Sbjct: 421 PALMVTAEKDFVLVPQMSKHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 480
Query: 547 RNPPVVSKM 555
RNPPVVSKM
Sbjct: 481 RNPPVVSKM 489
>gb|EAW63551.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_e [Homo sapiens]
Length = 489
Score = 748 bits (1932), Expect = 0.0, Method: Composition-based stats.
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 67 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 126
MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW
Sbjct: 1 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 60
Query: 127 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 186
LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI
Sbjct: 61 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 120
Query: 187 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 246
GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP
Sbjct: 121 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 180
Query: 247 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 306
RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE
Sbjct: 181 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 240
Query: 307 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 366
EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN
Sbjct: 241 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 300
Query: 367 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 426
PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG
Sbjct: 301 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAG 360
Query: 427 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 486
GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI
Sbjct: 361 GLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILI 420
Query: 487 PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 546
PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA
Sbjct: 421 PALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDA 480
Query: 547 RNPPVVSKM 555
RNPPVVSKM
Sbjct: 481 RNPPVVSKM 489
>ref|NP_001087143.1| epoxide hydrolase 2, cytoplasmic [Xenopus laevis]
gb|AAH78066.1| Ephx2-prov protein [Xenopus laevis]
Length = 560
Score = 738 bits (1907), Expect = 0.0, Method: Composition-based stats.
Identities = 312/558 (55%), Positives = 404/558 (72%), Gaps = 6/558 (1%)
Query: 3 LRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQ 62
R +FDL GVL P R E +L LP G L + F + G EG +G+I S+
Sbjct: 4 KRFVLFDLGGVLLTPGPQSAFQRLETSLHLPSGFLQNVFTRSGSEGPFAMAERGKIPFSK 63
Query: 63 WIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAIL 122
++ M + CR +E + V LP++FS+++ F IN+PML+AA+ LR GF T +L
Sbjct: 64 FVAEMNKECRAFAEESGVSLPESFSLEQAFHGMFENGGINKPMLKAAVKLRHHGFKTCVL 123
Query: 123 TNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVF 182
TN W+DD +R A+++ L HFD ++ESC++GM KPE QIY++ L L A P E +F
Sbjct: 124 TNNWIDDSPQRSLSAEVLSSLSRHFDLVVESCRIGMRKPETQIYEYALKLLHAKPKETIF 183
Query: 183 LDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYV 242
LDDIGANLKPAR++G+ T+LV+DT+TALKEL+ ++ + L+ P NP ++HG+V
Sbjct: 184 LDDIGANLKPAREMGIATVLVKDTETALKELQALSNVPLIENEEVAPIPANPDKVTHGFV 243
Query: 243 TVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAP 302
TVKP V+LH+VE+G+GP +CLCHGFPESWYSWR+QIPALA AG+RV+A DMKGYG+SSAP
Sbjct: 244 TVKPGVKLHYVEMGNGPVICLCHGFPESWYSWRFQIPALADAGFRVIAFDMKGYGDSSAP 303
Query: 303 PEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPF 362
EIEEY E +CK++V+FLD LG+SQA FIGHDWGG +VW MALFYPERVRAVASLNTPF
Sbjct: 304 HEIEEYSQEQICKDLVSFLDALGISQASFIGHDWGGAVVWNMALFYPERVRAVASLNTPF 363
Query: 363 IPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD-----ESVL 417
+ P ++ LE IKANP+FDYQLYFQEPGVAEAELE+NL RTFK FR S + L
Sbjct: 364 FTSEPGVNALERIKANPIFDYQLYFQEPGVAEAELEKNLERTFKVFFRGSSEKDRLPTTL 423
Query: 418 SMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWAC 477
+ V E GG+ V + E+ LS ++ E ++ +YV QFKKSGFRGPLNWYRNM+RN +W+
Sbjct: 424 TTMNVRERGGILVGTDEDTPLSSIINEADLHYYVAQFKKSGFRGPLNWYRNMQRNSEWSI 483
Query: 478 KSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQI 537
+ G KIL+PALMVTA KDFVL+P M++ ME+ IP+L RGHIE+C HWTQM++P VN+I
Sbjct: 484 SAHGWKILVPALMVTAGKDFVLLPIMTKGMENLIPNLSRGHIEECSHWTQMERPAAVNEI 543
Query: 538 LIKWLDSDARNPPVVSKM 555
LIKWL N PV SK+
Sbjct: 544 LIKWLGEVL-NLPVTSKL 560
>ref|NP_001006912.1| epoxide hydrolase 2, cytoplasmic [Xenopus tropicalis]
gb|AAH75370.1| Epoxide hydrolase 2, cytoplasmic [Xenopus tropicalis]
Length = 560
Score = 736 bits (1901), Expect = 0.0, Method: Composition-based stats.
Identities = 317/559 (56%), Positives = 407/559 (72%), Gaps = 6/559 (1%)
Query: 2 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLS 61
R +FDL GVL P R E +L+LP G L + F + G EG R +G+I S
Sbjct: 3 ARRFVLFDLGGVLLTPGPQVAFQRLERSLSLPSGFLQNVFVRSGSEGPFARAERGQIPFS 62
Query: 62 QWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAI 121
++I M++ C+ +E + V LP +FS+++ F + IN+PML+AA+ LR GF T +
Sbjct: 63 KFIAEMDKECKAFAEESGVSLPDSFSLEQTFHGMFESGGINKPMLKAAVTLRHHGFKTCV 122
Query: 122 LTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVV 181
LTN W+DD +R A+L L HFD ++ESC+ GM KPE QIY + L LKA+P E +
Sbjct: 123 LTNNWIDDSPQRSHSAELFSSLNRHFDLVVESCRTGMRKPETQIYDYALKMLKANPKETI 182
Query: 182 FLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGY 241
FLDDIGANLKPAR++G+ T+LV+DT+TALKEL+ ++G+ L P NP +++HG
Sbjct: 183 FLDDIGANLKPAREMGIATVLVKDTETALKELQALSGVPLFENEEVTPVPANPDNVTHGS 242
Query: 242 VTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSA 301
VTVKP V+LH+VE+G+GP +CLCHGFPESWYSWR+QIPALA AG+RV+A DMKGYG+SSA
Sbjct: 243 VTVKPGVQLHYVEMGNGPVICLCHGFPESWYSWRFQIPALADAGFRVIAFDMKGYGDSSA 302
Query: 302 PPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTP 361
P EIEEY E +CK++V+FLD +G+SQA FIGHDWGG +VW MALFYPERVRAVASLNTP
Sbjct: 303 PQEIEEYSQEQICKDLVSFLDVMGISQASFIGHDWGGAVVWNMALFYPERVRAVASLNTP 362
Query: 362 FIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESV----- 416
F ++P ++ LE IKANP+FDYQLYFQEPGVAEAELE++L RTFK FR S E
Sbjct: 363 FFTSDPGVNALERIKANPIFDYQLYFQEPGVAEAELEKDLERTFKVFFRGSSEKDRLATS 422
Query: 417 LSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWA 476
L+ V E GG+ V + E+P LS ++ E ++Q+YV QFKKSGFRGPLNWYRNM+RN +W
Sbjct: 423 LTTMNVRERGGILVGTDEDPPLSSIINEADLQYYVAQFKKSGFRGPLNWYRNMQRNSEWN 482
Query: 477 CKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQ 536
+ G KIL+PALMVTA KDFVL+P M++ ME+ IP+L RGHIE+C HWTQM++P VN
Sbjct: 483 ISAHGWKILVPALMVTAGKDFVLLPIMTKGMENLIPNLSRGHIEECSHWTQMERPAAVNG 542
Query: 537 ILIKWLDSDARNPPVVSKM 555
ILIKWL N PV SK+
Sbjct: 543 ILIKWLAEV-HNLPVTSKL 560
>gb|EDL85377.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_b [Rattus norvegicus]
Length = 512
Score = 727 bits (1878), Expect = 0.0, Method: Composition-based stats.
Identities = 373/513 (72%), Positives = 445/513 (86%), Gaps = 3/513 (0%)
Query: 44 GGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINR 103
PEG T +LMKG+IT SQW+PLM+E+CRK S+ LP+NFSI EIF +A++AR INR
Sbjct: 2 KFPEGPTEQLMKGKITFSQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINR 61
Query: 104 PMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEP 163
PMLQAA L+KKGFTT I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEP
Sbjct: 62 PMLQAAAALKKKGFTTCIITNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEP 121
Query: 164 QIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLN 223
QIYKF+LDTLKA P+EVVFLDD G+NLKPARD+GMVTILV+DT +AL+ELEKVTG Q
Sbjct: 122 QIYKFVLDTLKAKPNEVVFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFPE 181
Query: 224 TPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQ 283
P P+P S N D+SHGYVTVKP + LHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQ
Sbjct: 182 APLPVPCSPN--DVSHGYVTVKPGICLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQ 239
Query: 284 AGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWY 343
AG+RVLA+DMKGYG+SS+PPEIEEY ME+LC+EMVTFL+KLG+ QAVFIGHDW G+LVW
Sbjct: 240 AGFRVLAIDMKGYGDSSSPPEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWN 299
Query: 344 MALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSR 403
MALF+PERVRAVASLNTP +P NP +SP+E I++ PVF+YQLYFQEPGVAEAELE+N+SR
Sbjct: 300 MALFHPERVRAVASLNTPLMPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSR 359
Query: 404 TFKSLFRASDE-SVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGP 462
TFKS FR SD+ +L+++K E GG+ V +PE+P +S++ TEEEI++Y+QQFKKSGFRGP
Sbjct: 360 TFKSFFRTSDDMGLLTVNKATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGP 419
Query: 463 LNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDC 522
LNWYRN ERNWKW CK+LGRKIL+PALMVTAEKD VL P+MS++ME+WIP LKRGHIEDC
Sbjct: 420 LNWYRNTERNWKWNCKALGRKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDC 479
Query: 523 GHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM 555
GHWTQ++KP EVNQILIKWL ++ +NP V SK+
Sbjct: 480 GHWTQIEKPAEVNQILIKWLKTEIQNPSVTSKI 512
>ref|XP_001380051.1| PREDICTED: similar to soluble epoxide hydrolase [Monodelphis
domestica]
Length = 562
Score = 725 bits (1873), Expect = 0.0, Method: Composition-based stats.
Identities = 343/562 (61%), Positives = 429/562 (76%), Gaps = 7/562 (1%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M LRAA+FDL GVL P++ + + EEALALPRG LN +GG E L+KGEIT
Sbjct: 1 MGLRAALFDLGGVLVHPSMNIIFSQAEEALALPRGFLNKVITQGGLESPYVHLIKGEITF 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQW+PLMEE+CRK S + CLP+ FS+++IF+ IS KIN PML+AA+ LR KG+ T
Sbjct: 61 SQWVPLMEEDCRKLSVASNFCLPEQFSLQKIFEDMISEGKINYPMLRAAITLRNKGYKTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
ILTN WLDD +R+ +AQLMC L HFD +IESC++GMVKP+P+IYKF L+ LK +P E
Sbjct: 121 ILTNNWLDDGLQRNVIAQLMCTLSKHFDLVIESCRIGMVKPDPEIYKFALEALKVAPHEA 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
VFLDD GANLK AR+LGMVTIL QDTD ALKELEK TG+Q N P + +PS+++HG
Sbjct: 181 VFLDDTGANLKKARELGMVTILAQDTDMALKELEKSTGVQFPNHDMERPIAVHPSNIAHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV VKP V+LHFVE GSGP VCL HGFPE WYSW+ QIP L +AG+RV+A+D+KG+G+SS
Sbjct: 241 YVEVKPGVQLHFVEKGSGPVVCLFHGFPEFWYSWKCQIPVLVEAGFRVIALDLKGFGDSS 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
AP EIEEY EV+CKE++TFLDKL +SQA+ IGHDWGG+LVW MA+FYPERVRAVAS+N+
Sbjct: 301 APYEIEEYSQEVICKELITFLDKLDISQAICIGHDWGGLLVWNMAIFYPERVRAVASVNS 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF P +P + E +K NPVF+YQ YFQ+PGVAEAELEQ+L+RTFK LFRASDE + M
Sbjct: 361 PFFPPDPVVPLKEKLKKNPVFNYQFYFQKPGVAEAELEQDLTRTFKILFRASDERKVCML 420
Query: 421 KVCEAGG-------LFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNW 473
G + E P LS M+TEE+I +YVQQ+KKSGFRGPLNWYRN + NW
Sbjct: 421 HTGTIVGNRGLFFIGILKKIENPFLSWMLTEEDINYYVQQYKKSGFRGPLNWYRNHDANW 480
Query: 474 KWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTE 533
+W+C + RKIL+PALMV AE D VL P++S++ME WIPHLKR +I++CGHWTQ+++P E
Sbjct: 481 RWSCMATKRKILVPALMVIAENDVVLSPKLSENMEKWIPHLKRAYIKNCGHWTQLERPRE 540
Query: 534 VNQILIKWLDSDARNPPVVSKM 555
+NQILI+WL + P +VS +
Sbjct: 541 LNQILIEWLKDVTKTPSMVSLL 562
>gb|EDL36006.1| epoxide hydrolase 2, cytoplasmic, isoform CRA_b [Mus musculus]
Length = 501
Score = 715 bits (1846), Expect = 0.0, Method: Composition-based stats.
Identities = 372/503 (73%), Positives = 443/503 (88%), Gaps = 3/503 (0%)
Query: 54 MKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLR 113
MKG+IT SQW+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+
Sbjct: 1 MKGKITFSQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALK 60
Query: 114 KKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTL 173
KKGFTT I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTL
Sbjct: 61 KKGFTTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTL 120
Query: 174 KASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCN 233
KA P+EVVFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P N
Sbjct: 121 KAKPNEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPC--N 178
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
P+D+SHGYVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DM
Sbjct: 179 PNDVSHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDM 238
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
KGYG+SS+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVR
Sbjct: 239 KGYGDSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVR 298
Query: 354 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD 413
AVASLNTPF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASD
Sbjct: 299 AVASLNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASD 358
Query: 414 E-SVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERN 472
E +++HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERN
Sbjct: 359 ETGFIAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERN 418
Query: 473 WKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPT 532
WKW+CK LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPT
Sbjct: 419 WKWSCKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPT 478
Query: 533 EVNQILIKWLDSDARNPPVVSKM 555
EVNQILIKWL ++ +NP V SK+
Sbjct: 479 EVNQILIKWLQTEVQNPSVTSKI 501
>gb|AAM28238.1| ovary-selective epoxide hydrolase [Mus musculus]
Length = 536
Score = 703 bits (1815), Expect = 0.0, Method: Composition-based stats.
Identities = 367/499 (73%), Positives = 438/499 (87%), Gaps = 3/499 (0%)
Query: 58 ITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGF 117
I S+W+PLM+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGF
Sbjct: 40 IHTSEWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGF 99
Query: 118 TTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASP 177
TT I+TN WLDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P
Sbjct: 100 TTCIVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKP 159
Query: 178 SEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDM 237
+EVVFLDD G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P NP+D+
Sbjct: 160 NEVVFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPC--NPNDV 217
Query: 238 SHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYG 297
SHGYVTVKP +RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG
Sbjct: 218 SHGYVTVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYG 277
Query: 298 ESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVAS 357
+SS+PPEIEEY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVAS
Sbjct: 278 DSSSPPEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVAS 337
Query: 358 LNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SV 416
LNTPF+P +P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE
Sbjct: 338 LNTPFMPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGF 397
Query: 417 LSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWA 476
+++HK E GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+
Sbjct: 398 IAVHKATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWS 457
Query: 477 CKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQ 536
CK LGRKIL+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQ
Sbjct: 458 CKGLGRKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQ 517
Query: 537 ILIKWLDSDARNPPVVSKM 555
ILIKWL ++ +NP V SK+
Sbjct: 518 ILIKWLQTEVQNPSVTSKI 536
>gb|ABU95055.1| epoxide hydrolase 2C [Mus musculus]
Length = 488
Score = 694 bits (1791), Expect = 0.0, Method: Composition-based stats.
Identities = 362/490 (73%), Positives = 431/490 (87%), Gaps = 3/490 (0%)
Query: 67 MEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILTNTW 126
M+E+ RK S+ LP+NFSI +IF +A++AR INRPMLQAA+ L+KKGFTT I+TN W
Sbjct: 1 MDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTCIVTNNW 60
Query: 127 LDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFLDDI 186
LDD +RD LAQ+MCEL HFDFLIESCQVGM+KPEPQIY FLLDTLKA P+EVVFLDD
Sbjct: 61 LDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEVVFLDDF 120
Query: 187 GANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKP 246
G+NLKPARD+GMVTILV +T +AL+ELEKVTG Q P P+P NP+D+SHGYVTVKP
Sbjct: 121 GSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPC--NPNDVSHGYVTVKP 178
Query: 247 RVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIE 306
+RLHFVE+GSGPA+CLCHGFPESW+SWRYQIPALAQAG+RVLA+DMKGYG+SS+PPEIE
Sbjct: 179 GIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSPPEIE 238
Query: 307 EYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPAN 366
EY ME+LCKEMVTFLDKLG+ QAVFIGHDW G++VW MALFYPERVRAVASLNTPF+P +
Sbjct: 239 EYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPD 298
Query: 367 PNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-SVLSMHKVCEA 425
P++SP++ I++ PVF+YQLYFQEPGVAEAELE+N+SRTFKS FRASDE +++HK E
Sbjct: 299 PDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEI 358
Query: 426 GGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKIL 485
GG+ VN+PE+P+LS++ TEEEI+FY+QQFKK+GFRGPLNWYRN ERNWKW+CK LGRKIL
Sbjct: 359 GGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKIL 418
Query: 486 IPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSD 545
+PALMVTAEKD VL P+MS++ME WIP LKRGHIEDCGHWTQ++KPTEVNQILIKWL ++
Sbjct: 419 VPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWLQTE 478
Query: 546 ARNPPVVSKM 555
+NP V SK+
Sbjct: 479 VQNPSVTSKI 488
>ref|NP_001028817.1| epoxide hydrolase 2, cytoplasmic [Gallus gallus]
gb|AAZ38461.1| soluble epoxide hydrolase [Gallus gallus]
Length = 562
Score = 691 bits (1784), Expect = 0.0, Method: Composition-based stats.
Identities = 314/562 (55%), Positives = 418/562 (74%), Gaps = 7/562 (1%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M R A+FDL GVL P + LG E + ALPR L D GG + ++M+G+ITL
Sbjct: 1 MARRFALFDLGGVLFGPGLQHFLGSCERSYALPRNFLRDVLFAGGSDSPHAKVMRGQITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQ ++E CR+ + TA + LP FSI +F++ + +N P+L+AA MLR+ GF T
Sbjct: 61 SQLFLEVDEGCRQHASTAGITLPTTFSIAHVFEEMAAKGTLNAPLLRAASMLRRNGFKTC 120
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
+ TN W+DD R + L+ ++ HFD LIESC+VG+ KP+P+IY + L+ L+A P EV
Sbjct: 121 VFTNNWVDDSMGRLFTSSLLTVVQRHFDLLIESCRVGLHKPDPRIYTYALEVLQAQPQEV 180
Query: 181 VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG 240
+FLDDIG NLKPAR++GM TILV+DTDT LKEL++++G+QLL PLPT+C+P+ MSHG
Sbjct: 181 IFLDDIGENLKPAREMGMATILVRDTDTVLKELQELSGVQLLQQEEPLPTTCDPATMSHG 240
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
YV ++P V+LHFVE+G GPA+CLCHGFPESW SWRYQIPALA AG+RV+A++MKGYGES+
Sbjct: 241 YVPIRPGVQLHFVEMGHGPAICLCHGFPESWLSWRYQIPALADAGFRVIALEMKGYGEST 300
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
APPEIEEY E +CK++ FLDKLG+ QAVFIGHDWGG +VW MALFYPERVRAVASLNT
Sbjct: 301 APPEIEEYSQEQICKDLTIFLDKLGIPQAVFIGHDWGGAVVWNMALFYPERVRAVASLNT 360
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE-----S 415
P+ PA+P + +E++K+ P+FDYQ YFQEPGVAEAELE+++ RT K+L R++ S
Sbjct: 361 PYRPADPTVDIVETMKSFPMFDYQFYFQEPGVAEAELEKDIGRTLKALIRSTRPEDRLHS 420
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
V + V E GGL V PE+ S ++ E+Q+Y+++F++SGFRGPLNWYRNM NW+W
Sbjct: 421 VPGLLGVQERGGLLVGFPEDIPESLILHGAELQYYIERFQRSGFRGPLNWYRNMRPNWRW 480
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 535
A + RKIL+PALMVTA KD VL+P MS+ ME+WIP L+RGH+E CGHWTQM++P +N
Sbjct: 481 ALSAKDRKILMPALMVTAGKDVVLLPSMSKGMEEWIPQLRRGHLEACGHWTQMERPAALN 540
Query: 536 QILIKWLDSDARNPP--VVSKM 555
+IL++WL+ + VS++
Sbjct: 541 RILVEWLEGLPPDGAMLRVSRL 562
>gb|ACC95977.1| soluble epoxide hydrolase-like protein 1 [Strongylocentrotus
purpuratus]
Length = 562
Score = 661 bits (1705), Expect = 0.0, Method: Composition-based stats.
Identities = 243/557 (43%), Positives = 343/557 (61%), Gaps = 10/557 (1%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M +A +FDL GVL P L + E L LP L A +G P+ A R+ +GE T
Sbjct: 5 MKKKAVLFDLGGVLFEP-PQNALRKYGEQLGLPGSFLEKAMIQGRPDNAFCRMERGESTA 63
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Q+ ++C+ S+ LPK+F+ +FD ++ + + ML A +L++ G TA
Sbjct: 64 RQFAEEFTKDCQTLSKEEGQVLPKDFNASSMFDTFMNIKMV-PDMLNAVSVLKQNGVKTA 122
Query: 121 ILTNTWLDDRAERDGLAQLMCELKM-HFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
+TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L L E
Sbjct: 123 AVTNNYIDDREQNSLGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKLGVKAEE 182
Query: 180 VVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSH 239
VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P S + + H
Sbjct: 183 AVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVFQEAKP--VSVHHERVPH 240
Query: 240 GYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGES 299
Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A AG+RV+AMDMKGYGES
Sbjct: 241 SYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAAAGFRVIAMDMKGYGES 300
Query: 300 SAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
S PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV AV +
Sbjct: 301 SNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVSAVGGIC 360
Query: 360 TPFIPANPNMSPLESIKANPVFD-YQLYFQEPGVAEAELEQNLSRTFKSLFRAS---DES 415
TPF PAN M+P E+I NP YQLYF E G EAE+E N+ + K+ R E
Sbjct: 361 TPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRPLELKEI 420
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
S+ V GG+ P++ + S ++TE+++Q+YV+QFK G R LNWYR ME NWK+
Sbjct: 421 GFSVAGVRAKGGIMAGIPDDIN-STLLTEDDVQYYVKQFKTCGLRSMLNWYRTMEVNWKF 479
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVN 535
+++GRK+ +PALMVT D VL P +S+ M+ ++ +L R HIED GHW +++P ++N
Sbjct: 480 NHRAIGRKLYMPALMVTCAWDEVLPPSVSKFMDPFVVNLTRAHIEDSGHWASLEQPKKLN 539
Query: 536 QILIKWLDSDARNPPVV 552
+IL+ WL+ ++
Sbjct: 540 KILVDWLNKVHKDSNRP 556
>ref|NP_001008642.1| epoxide hydrolase 2, cytoplasmic [Danio rerio]
gb|AAH86714.1| Zgc:101645 [Danio rerio]
gb|AAI65172.1| Ephx2 protein [synthetic construct]
Length = 557
Score = 653 bits (1686), Expect = 0.0, Method: Composition-based stats.
Identities = 269/547 (49%), Positives = 367/547 (67%), Gaps = 7/547 (1%)
Query: 2 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLS 61
+A +F L G + P + + EE + +G + + K G + A R KG+ TL+
Sbjct: 1 MKKAVLFSLWGGVVTPQIGQAFQKFEETTGISKGFIKNVETKLGSDNALHRAEKGKTTLA 60
Query: 62 QWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAI 121
Q IP + C+K + + LP FS +++FD + N L AA +LR+ G T I
Sbjct: 61 QMIPEFDAECQKVAADQGLSLPAQFSTQKLFDDMGKV-EFNMTFLDAAAVLRRNGIATGI 119
Query: 122 LTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVV 181
L N W+DD A+R +A+++ L+ FD ++ SC G+ PEP +K L+ L P E +
Sbjct: 120 LANIWVDDTAQRGSIARVLSVLESRFDLVLRSCHAGVRIPEPDFFKHALEKLAVKPQEAL 179
Query: 182 FLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGY 241
+LD ++K A LG++ + V+D AL E++K+TGI++ + P +P +SHGY
Sbjct: 180 WLDVDEESVKAAEGLGIMAVQVKDVTEALTEIQKLTGIEVTSDLQPPSC--DPEKVSHGY 237
Query: 242 VTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSA 301
V +KP V++H+VE+G GP V LCHGFPESW+SWRYQIPALA AG+RVLA DMKGYG S+A
Sbjct: 238 VNIKPGVKIHYVEMGDGPPVLLCHGFPESWFSWRYQIPALADAGFRVLAPDMKGYGGSTA 297
Query: 302 PPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTP 361
PP+IEEY E + ++VTFLDK+ ++Q +GHDWGG+LVW MA F+PERVRAVASLNTP
Sbjct: 298 PPDIEEYSQEQIMLDLVTFLDKMAIAQVTLVGHDWGGVLVWNMAQFHPERVRAVASLNTP 357
Query: 362 FIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE----SVL 417
P +PN +P+E + A P+FDYQ+YFQ+PGVAEAELE+NL RTFK +F +S + L
Sbjct: 358 LFPVDPNTNPMEKLMAIPIFDYQIYFQKPGVAEAELEKNLKRTFKLMFISSSDTGGFPKL 417
Query: 418 SMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWAC 477
S VC+ GGLFV SP++P S M++ +QFY +Q+ KSGFRGPLNWYRN ERNW+W
Sbjct: 418 SPAGVCQRGGLFVGSPDDPPRSSMLSVSALQFYTEQYSKSGFRGPLNWYRNYERNWRWMV 477
Query: 478 KSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQI 537
KIL+PALMVTA KD VL+P + ME+ IP+L RGHIE+CGHWTQM++P E+N+I
Sbjct: 478 SRPRAKILMPALMVTAGKDPVLLPAFATGMENLIPNLSRGHIEECGHWTQMERPAELNKI 537
Query: 538 LIKWLDS 544
LI WL
Sbjct: 538 LISWLKE 544
>ref|XP_001521600.1| PREDICTED: similar to epoxide hydrolase 2, cytoplasmic, partial
[Ornithorhynchus anatinus]
Length = 530
Score = 601 bits (1550), Expect = e-170, Method: Composition-based stats.
Identities = 301/498 (60%), Positives = 372/498 (74%), Gaps = 15/498 (3%)
Query: 64 IPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAILT 123
+PL++E CR S A + LP FSI+ +FD+ S +IN PMLQAA+ LR +G+ T IL+
Sbjct: 2 VPLLDEACRDISAAAGLQLPTPFSIRRVFDEMGSGAEINIPMLQAAIALRNRGWKTGILS 61
Query: 124 NTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVFL 183
NTW+DD +R A++ C L HFD +ESC VG+ KP+P IY L+ L P E V L
Sbjct: 62 NTWVDDSPQRGQWAEISCALAKHFDLRVESCHVGVAKPDPGIYLLALEALGVRPHEAVCL 121
Query: 184 DDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSD---MSHG 240
DD ANL+ A +LG+VT+ +DT AL++LE+VTG+Q+ TP P +P
Sbjct: 122 DDTEANLRAALELGLVTVQARDTAAALEKLEQVTGMQVWTTPVMPPPPLHPLSLAPWCSP 181
Query: 241 YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS 300
+ ++P V+LHFVE G+GPAVCLCHGFPESW+SWRYQIPALA AG+RV+A+DMKGYG+SS
Sbjct: 182 PLPIQPGVQLHFVEAGTGPAVCLCHGFPESWFSWRYQIPALADAGFRVIALDMKGYGDSS 241
Query: 301 APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT 360
AP IEEY E +CKE VTFLDKLG+SQAVFIGHDWGGM VW MALFYPERVRAVASLNT
Sbjct: 242 APQAIEEYSQEEMCKEAVTFLDKLGISQAVFIGHDWGGMFVWNMALFYPERVRAVASLNT 301
Query: 361 PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH 420
PF+PA+P++ +E I+A PV DYQLYFQEPGVAEAELE NLSRT K L RASDE
Sbjct: 302 PFMPADPSVPAMERIRALPVCDYQLYFQEPGVAEAELEANLSRTLKLLIRASDE------ 355
Query: 421 KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL 480
KV GGL V PE SR++ EE+++FYVQQF+KSGFRGPLNWYRNMERNW+W+C ++
Sbjct: 356 KVGSPGGLLVGMPEFSPTSRILKEEDLRFYVQQFEKSGFRGPLNWYRNMERNWRWSCTAV 415
Query: 481 GRKILIPALMVTAEKDFVLVPQMSQHMEDWIP---HLKRGHIEDCGHWTQMDKPTEVNQI 537
GRKI++PALM+TA KD +L PQ S+HMEDW+ +RGHIE+CGHWTQM++PTE+NQI
Sbjct: 416 GRKIMVPALMITAGKDPILTPQTSRHMEDWVRSWGSGERGHIEECGHWTQMERPTELNQI 475
Query: 538 LIKWLDSDARNPPVVSKM 555
LIKWL P VSK+
Sbjct: 476 LIKWLKEL---PAGVSKL 490
>ref|XP_795168.2| PREDICTED: similar to Ephx2-prov protein [Strongylocentrotus
purpuratus]
Length = 507
Score = 584 bits (1507), Expect = e-165, Method: Composition-based stats.
Identities = 222/505 (43%), Positives = 317/505 (62%), Gaps = 9/505 (1%)
Query: 53 LMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALML 112
+ +GE T Q+ ++C+ S+ LPK+F+ +FD ++ + + ML A +L
Sbjct: 1 MERGESTARQFAEEFTKDCQTLSKEEGQVLPKDFNASSMFDTFMNIKMV-PDMLNAVSVL 59
Query: 113 RKKGFTTAILTNTWLDDRAERDGLAQLMCELKM-HFDFLIESCQVGMVKPEPQIYKFLLD 171
++ G TA +TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L
Sbjct: 60 KQNGVKTAAVTNNYIDDREQNSLGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALK 119
Query: 172 TLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTS 231
L E VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P S
Sbjct: 120 KLGVKAEEAVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVFQEAKP--VS 177
Query: 232 CNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAM 291
+ + H Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A G+RV+AM
Sbjct: 178 VHHERVPHSYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAATGFRVIAM 237
Query: 292 DMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPER 351
DMKGYGESS PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+R
Sbjct: 238 DMKGYGESSNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDR 297
Query: 352 VRAVASLNTPFIPANPNMSPLESIKANPVFD-YQLYFQEPGVAEAELEQNLSRTFKSLFR 410
V AV + TPF PAN M+P E+I NP YQLYF E G EAE+E N+ + K+ R
Sbjct: 298 VSAVGGICTPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMR 357
Query: 411 AS---DESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYR 467
E S+ V GG+ P++ + S ++TE+++Q+YV+QFK G R LNWYR
Sbjct: 358 RPLELKEIGFSVAGVRAKGGIMAGIPDDIN-STLLTEDDVQYYVKQFKTCGLRSMLNWYR 416
Query: 468 NMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQ 527
ME NWK+ +++GRK+ +PALMVT D VL P +S+ M+ ++ +L R HIED GHW
Sbjct: 417 TMEVNWKFNHRAIGRKLYMPALMVTCAWDEVLPPSVSKFMDPFVVNLTRAHIEDSGHWAS 476
Query: 528 MDKPTEVNQILIKWLDSDARNPPVV 552
+++P ++N+IL+ WL+ ++
Sbjct: 477 LEQPKKLNKILVDWLNKVHKDSNRP 501
>ref|XP_795076.2| PREDICTED: similar to Ephx2-prov protein, partial
[Strongylocentrotus purpuratus]
Length = 492
Score = 576 bits (1486), Expect = e-162, Method: Composition-based stats.
Identities = 222/515 (43%), Positives = 304/515 (59%), Gaps = 32/515 (6%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M +A +FDL GVL P L + E L LP D F
Sbjct: 5 MKKKAVLFDLGGVLFEP-PQNALRKYGEQLGLPG---QDLF------------------- 41
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Q+ ++C+ S+ LPK+F+ +FD ++ + + ML A +L++ G TA
Sbjct: 42 -QFAEEFTKDCQTVSKEEGQVLPKDFNASSMFDTFMNIKMV-PDMLNAVSVLKQNGVKTA 99
Query: 121 ILTNTWLDDRAERDGLAQLMCELKM-HFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
+TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L L E
Sbjct: 100 AVTNNYIDDREQNSVGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKLGVKAEE 159
Query: 180 VVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSH 239
VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P S + + H
Sbjct: 160 AVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVCQEAKP--VSVHHERVPH 217
Query: 240 GYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGES 299
Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A AG+RV+AMDMKGYGES
Sbjct: 218 SYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAAAGFRVIAMDMKGYGES 277
Query: 300 SAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
S PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV AV +
Sbjct: 278 SNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVSAVGGIC 337
Query: 360 TPFIPANPNMSPLESIKANPVFD-YQLYFQEPGVAEAELEQNLSRTFKSLFRAS---DES 415
TPF PAN M+P E+I NP YQLYF E G EAE+E N+ + K+ R E
Sbjct: 338 TPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRPLELKEI 397
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
S+ V GG+ P++ LS ++TE+++Q+YV+QFK G R LNWYR ME NWK+
Sbjct: 398 GFSVAGVRAKGGIMAGIPDDIKLSTLLTEDDLQYYVKQFKTCGLRSMLNWYRTMEVNWKF 457
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDW 510
+++GRK+ +PALMVT D VL P S+ M+ +
Sbjct: 458 NHRAIGRKLYMPALMVTCAGDAVLPPSASKFMDPF 492
>ref|XP_001190554.1| PREDICTED: similar to Ephx2-prov protein [Strongylocentrotus
purpuratus]
Length = 595
Score = 576 bits (1485), Expect = e-162, Method: Composition-based stats.
Identities = 222/515 (43%), Positives = 304/515 (59%), Gaps = 32/515 (6%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
M +A +FDL GVL P L + E L LP D F
Sbjct: 5 MKKKAVLFDLGGVLFEP-PQNALRKYGEQLGLPG---QDLF------------------- 41
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
Q+ ++C+ S+ LPK+F+ +FD ++ + + ML A +L++ G TA
Sbjct: 42 -QFAEEFTKDCQTVSKEEGQVLPKDFNASSMFDTFMNIKMV-PDMLNAVSVLKQNGVKTA 99
Query: 121 ILTNTWLDDRAERDGLAQLMCELKM-HFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSE 179
+TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L L E
Sbjct: 100 AVTNNYIDDREQNSVGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKLGVKAEE 159
Query: 180 VVFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSH 239
VFLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P S + + H
Sbjct: 160 AVFLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVCQEAKP--VSVHHERVPH 217
Query: 240 GYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGES 299
Y T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A AG+RV+AMDMKGYGES
Sbjct: 218 SYATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAAAGFRVIAMDMKGYGES 277
Query: 300 SAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLN 359
S PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV AV +
Sbjct: 278 SNPPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVSAVGGIC 337
Query: 360 TPFIPANPNMSPLESIKANPVFD-YQLYFQEPGVAEAELEQNLSRTFKSLFRAS---DES 415
TPF PAN M+P E+I NP YQLYF E G EAE+E N+ + K+ R E
Sbjct: 338 TPFFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRPLELKEI 397
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
S+ V GG+ P++ LS ++TE+++Q+YV+QFK G R LNWYR ME NWK+
Sbjct: 398 GFSVAGVRAKGGIMAGIPDDIKLSTLLTEDDLQYYVKQFKTCGLRSMLNWYRTMEVNWKF 457
Query: 476 ACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDW 510
+++GRK+ +PALMVT D VL P S+ M+ +
Sbjct: 458 NHRAIGRKLYMPALMVTCAGDAVLPPSASKFMDPF 492
>ref|XP_001184789.1| PREDICTED: similar to Ephx2-prov protein [Strongylocentrotus
purpuratus]
Length = 707
Score = 572 bits (1474), Expect = e-161, Method: Composition-based stats.
Identities = 218/495 (44%), Positives = 311/495 (62%), Gaps = 9/495 (1%)
Query: 63 WIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAIL 122
+ ++C+ S+ LPK+F+ +FD ++ + + ML A +L++ G TA +
Sbjct: 211 FAEEFTKDCQTLSKEEGQVLPKDFNASSMFDTFMNIKMV-PDMLNAVSVLKQNGVKTAAV 269
Query: 123 TNTWLDDRAERDGLAQLMCELKM-HFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVV 181
TN ++DDR + A +M L +FD +ESC+ G KP+ I+ L L E V
Sbjct: 270 TNNYIDDREQNSLGAGVMTTLSSFYFDHFVESCRFGKRKPDQSIFNEALKKLGVKAEEAV 329
Query: 182 FLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGY 241
FLDD+G N+K AR++G+ T+LV+DT ALKEL++VTGI + P S + + H Y
Sbjct: 330 FLDDLGPNVKAAREMGISTVLVKDTSAALKELQEVTGIDVFQEAKP--VSVHHERVPHSY 387
Query: 242 VTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSA 301
T + V+ H+V++GSGP V CHGFPESWY W+ QIPA+A G+RV+AMDMKGYGESS
Sbjct: 388 ATTRSGVKFHYVDIGSGPPVIFCHGFPESWYEWKSQIPAVAATGFRVIAMDMKGYGESSN 447
Query: 302 PPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTP 361
PPEIEEY +E +CK+M F+D L + QA FIGHDWGG VW A YP+RV AV + TP
Sbjct: 448 PPEIEEYTLERMCKDMAEFMDTLCIPQATFIGHDWGGFFVWNYATHYPDRVSAVGGICTP 507
Query: 362 FIPANPNMSPLESIKANPVFD-YQLYFQEPGVAEAELEQNLSRTFKSLFRAS---DESVL 417
F PAN M+P E+I NP YQLYF E G EAE+E N+ + K+ R E
Sbjct: 508 FFPANDTMNPWENINKNPGLYDYQLYFNEVGPPEAEIEANVEKFVKAFMRRPLELKEIGF 567
Query: 418 SMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWAC 477
S+ V GG+ P++ + S ++TE+++Q+YV+QFK G R LNWYR ME NWK+
Sbjct: 568 SVAGVRAKGGIMAGIPDDIN-STLLTEDDVQYYVKQFKTCGLRSMLNWYRTMEVNWKFNH 626
Query: 478 KSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQI 537
+++GRK+ +PALMVT D VL P +S+ M+ ++ +L R HIED GHW +++P ++N+I
Sbjct: 627 RAIGRKLYMPALMVTCAWDEVLPPSVSKFMDPFVVNLTRAHIEDSGHWASLEQPKKLNKI 686
Query: 538 LIKWLDSDARNPPVV 552
L+ WL+ ++
Sbjct: 687 LVDWLNKVHKDSNRP 701
>emb|CAG00866.1| unnamed protein product [Tetraodon nigroviridis]
Length = 535
Score = 567 bits (1462), Expect = e-160, Method: Composition-based stats.
Identities = 254/545 (46%), Positives = 341/545 (62%), Gaps = 19/545 (3%)
Query: 4 RAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQW 63
+A +F+ GV + GV E+ LP G L+ + +GA +R G +TL Q
Sbjct: 5 KAVLFNFWGVTVPSSPHGVCASLEKKRNLPEGFLSSLASRK--DGAMSRAEVGRLTLCQM 62
Query: 64 IPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISAR-KINRPMLQAALMLRKKGFTTAIL 122
P +E C + ++ LP ++S+ E+ DK A +N +L+ A +LR G+ TA+L
Sbjct: 63 APELEAECVQEAQARAAALPSDWSVAELVDKLREAMLDVNPAVLKMAAVLRSHGYLTAVL 122
Query: 123 TNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVF 182
N W+ D + G A+L+ L HFD +++SC+ G PE ++ L L + + ++
Sbjct: 123 ANHWVHDSGDTQGPARLLSHLGGHFDLVLQSCRTGHRVPEAAMFSAALQHLGVTSQQALW 182
Query: 183 LDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYV 242
LD +K A G+ ILV++ + AL +L TG+Q+ + + P CNP+++SHGYV
Sbjct: 183 LDADEDGVKAAEGEGLKAILVENAEDALSKLALHTGLQVDDAGSHTPP-CNPNEVSHGYV 241
Query: 243 TVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAP 302
++ V+ H+VE+G GP V LCHGFPESWYSWRYQIPALA AG+RVLA+DMKGYGES+AP
Sbjct: 242 AIRDGVKTHYVEMGEGPPVLLCHGFPESWYSWRYQIPALAYAGFRVLALDMKGYGESTAP 301
Query: 303 PEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPF 362
+I EY E +CK + Q +GHDWGG LVW MA F+PERVRA ASLNTP
Sbjct: 302 TDISEYTQEQMCK---------AIPQVTLVGHDWGGALVWSMAQFHPERVRAAASLNTPL 352
Query: 363 IPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDE----SVLS 418
NP S L I+ +FDYQ+YFQE GVAEAELE+NL RTFK F E LS
Sbjct: 353 FEFNP--STLRKIQDLGIFDYQVYFQEQGVAEAELEENLERTFKVFFSRGSERDIRPPLS 410
Query: 419 MHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACK 478
VC GGL V PE+ LS M+TE ++QFYV +++ GFR PLNWYR ME N KW+
Sbjct: 411 TAGVCARGGLLVGQPEDVPLSSMLTEADLQFYVSRYRDQGFRRPLNWYRAMEANRKWSSS 470
Query: 479 SLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQIL 538
RK+L+PALMVTA +D VL+P +S+ ME+ IP+L RGHIE+ GHWTQMD+P E N+IL
Sbjct: 471 CPNRKVLVPALMVTAGRDPVLLPSLSEGMENMIPNLSRGHIEESGHWTQMDRPAETNRIL 530
Query: 539 IKWLD 543
I WL
Sbjct: 531 IGWLQ 535
>ref|XP_001641873.1| predicted protein [Nematostella vectensis]
gb|EDO49810.1| predicted protein [Nematostella vectensis]
Length = 548
Score = 552 bits (1423), Expect = e-155, Method: Composition-based stats.
Identities = 214/556 (38%), Positives = 323/556 (58%), Gaps = 30/556 (5%)
Query: 2 TLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLS 61
+ A+FDL GV+A F + + +P LL F +L G+I+LS
Sbjct: 1 MFKLAIFDLGGVVATSLKFAI-EHYAWKMGVPYSLLQKLFLPSNENQPMWQLETGKISLS 59
Query: 62 QWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAI 121
Q+ E +E + LP FS+K +FD+ K+ ML AA L+ GF T I
Sbjct: 60 QFFVSASELISNLAEEEGIKLPPRFSLKTLFDQLYKTIKVVPEMLNAAAALKANGFRTCI 119
Query: 122 LTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVV 181
++N W DD ++ + ++ +FD ESC++G+ KP+P++YK + K P+EV+
Sbjct: 120 VSNNWTDDTETGQHVSG-LSLIRPYFDDFFESCKIGIRKPDPEMYKLVCKKFKVQPNEVL 178
Query: 182 FLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGY 241
FLDD+ +NL PA+++GM TILV+D +AL+ ++++TGI +L + S + H
Sbjct: 179 FLDDLPSNLAPAKEMGMATILVKDPISALRTVKEITGIDVLKAYPTPACTP--SSVPHSI 236
Query: 242 VTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVL---------AMD 292
V +K + +H+V++G G + L HGFPE WY W+YQ ++ Y VL A
Sbjct: 237 VQLKTGIMMHYVDIGHGHPIILLHGFPELWYIWKYQGTIIS---YGVLFEAKSDAKLACT 293
Query: 293 MKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERV 352
Y S ++ +++++ +D L L Q IGHDWGGM+ W +AL +P+R+
Sbjct: 294 QLLYSPSDKI---------IVFQDIISLMDLLLLRQVAVIGHDWGGMVAWDLALHHPDRI 344
Query: 353 RAVASLNTPFIPANPNMSPLESIKANPV-FDYQLYFQEPGVAEAELEQNLSRTFKSLFRA 411
RAVA++ TPF+P NP+++PL +KA P F YQLYF + G EAE E++L RTFK R
Sbjct: 345 RAVANM-TPFMPPNPDINPLLGLKAKPGVFQYQLYFHQEGPPEAEFEKDLRRTFKLFLRN 403
Query: 412 SDES---VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRN 468
+ E LS V E GG FV +PE+ S M+TEE++ ++V+ F+K+GFRGPLNWYRN
Sbjct: 404 ASEMEQIKLSTSDVLERGGFFVGTPEKVERSCMITEEDLDYFVENFRKTGFRGPLNWYRN 463
Query: 469 MERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQM 528
ME +WKW K RKIL P LM+T+ KD V++P + +M +P+L HIE+ H+T +
Sbjct: 464 MEVDWKWNLKIHPRKILQPVLMITSGKDPVILPAFAANMGAHVPNLSLAHIEESSHFTPI 523
Query: 529 DKPTEVNQILIKWLDS 544
D+P E+N +L+ WL
Sbjct: 524 DRPLELNNMLLDWLKR 539
>gb|ACC95978.1| soluble epoxide hydrolase-like protein 2 [Strongylocentrotus
purpuratus]
Length = 561
Score = 527 bits (1359), Expect = e-148, Method: Composition-based stats.
Identities = 186/551 (33%), Positives = 284/551 (51%), Gaps = 18/551 (3%)
Query: 3 LRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITLSQ 62
+ +FDL GV+ P L + E LPR + + +G RL +GEIT++Q
Sbjct: 4 KKVVLFDLGGVIVTP-PQRALLKYCEEAGLPRNFIFNVISQGRANNTFARLERGEITVTQ 62
Query: 63 WIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTAIL 122
+ E+ CR+ +E + +P +FS E+ + + ML A +L++ G T L
Sbjct: 63 FATEFEQECRRVAEAQSLVIPDSFSATEMVN--FKDPDLIPEMLNAVAVLKENGVQTCAL 120
Query: 123 TNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEVVF 182
TN ++D+ + R A + +FD +ESC++G+ KP+P I+ L L A S+ VF
Sbjct: 121 TNNYIDNTSNRAYAAGGLTAFTFYFDEFVESCRLGIRKPDPNIFHEALARLGAEASQAVF 180
Query: 183 LDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYV 242
LDD N K A LG+ +ILVQD TAL++L+ VTGI + P + +P +++H YV
Sbjct: 181 LDDSEVNTKAAEALGITSILVQDPKTALEQLKIVTGIDVFKQAGP--ITVHPDEVTHSYV 238
Query: 243 TVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAP 302
T + +VR HF ELGSGP V LCH F E W +WR +P LA AG+R +A+D+KG+GESS P
Sbjct: 239 TTRSKVRFHFTELGSGPPVVLCHDFEEDWEAWRSLMPELAIAGFRAIALDLKGFGESSKP 298
Query: 303 PEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPF 362
+ E+Y +++LC++M FLD LG++Q IG G W A +RVRAVA +NT
Sbjct: 299 TDTEQYTLKILCRDMTEFLDALGIAQVTLIGKGMGSAFAWTFANHTTDRVRAVAGINTSP 358
Query: 363 IPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKV 422
P+ + IK + F+ F +
Sbjct: 359 SVVIPDTLYGDQIKRIGSLQDYIKFRHCDRNNNNNPDIEMEQFYRIATCHSSDTNPTKHD 418
Query: 423 CEAGGLFVNSPE---EPSLSRMVTEEEIQ-------FYVQQFKKSGFRGPLNWYRNMERN 472
G+ V E + S++ + E + + + KS RG NW+RN N
Sbjct: 419 RCLQGIDVKDFELSTKASMNCLCIEADKRGKKQLGGHHRSTKSKSKSRGA-NWFRNNAAN 477
Query: 473 WKWACKSLGRKILIPALMVT-AEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKP 531
W+W + GR +LIPAL+VT + VP +S+ ++ WIP ++ H+ C T ++
Sbjct: 478 WEWNRRLNGRMLLIPALVVTSGQGSPKDVPDVSE-LKKWIPEVEHSHVSGCEIKTDRERS 536
Query: 532 TEVNQILIKWL 542
+E+N+IL KWL
Sbjct: 537 SELNRILRKWL 547
>ref|XP_001181957.1| PREDICTED: similar to soluble epoxide hydrolase, partial
[Strongylocentrotus purpuratus]
Length = 527
Score = 486 bits (1251), Expect = e-135, Method: Composition-based stats.
Identities = 175/519 (33%), Positives = 269/519 (51%), Gaps = 17/519 (3%)
Query: 35 GLLNDAFQKGGPEGATTRLMKGEITLSQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDK 94
+ + +G RL +GEIT++Q+ E+ CR+ +E + +P +FS E+ +
Sbjct: 1 NFIFNVISQGRANNTFARLERGEITVTQFATEFEQECRRVAEAQSLVIPDSFSATEMVN- 59
Query: 95 AISARKINRPMLQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESC 154
+ ML A +L++ G T LTN ++D+ + R A + +FD +ESC
Sbjct: 60 -FKDPDLIPEMLNAVAVLKENGVQTCALTNNYIDNTSNRAYAAGGLTAFTFYFDEFVESC 118
Query: 155 QVGMVKPEPQIYKFLLDTLKASPSEVVFLDDIGANLKPARDLGMVTILVQDTDTALKELE 214
++G+ KP+P I+ L L A S+ VFLDD N K A LG+ +ILVQD TAL++L+
Sbjct: 119 RLGIRKPDPNIFHEALARLGAEASQAVFLDDSEVNTKAAEALGITSILVQDPKTALEQLK 178
Query: 215 KVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSW 274
VTGI + P + +P +++H YVT + +VR HF ELGSGP V LCH F E W +W
Sbjct: 179 IVTGIDVFKQAGP--ITVHPDEVTHSYVTTRSKVRFHFTELGSGPPVVLCHDFEEDWEAW 236
Query: 275 RYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGH 334
R +P LA AG+R +A+D+KG+GESS P + E+Y +++LC++M FLD LG++Q IG
Sbjct: 237 RSLMPELAIAGFRAIALDLKGFGESSKPTDTEQYTLKILCRDMTEFLDALGIAQVTLIGK 296
Query: 335 DWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAE 394
G W A +RVRAVA +NT P+ + IK + F+
Sbjct: 297 GMGSAFAWTFANHTTDRVRAVAGINTSPSVVIPDTFYGDQIKRIGSLQDYIKFRHCDRNN 356
Query: 395 AELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPE---EPSLSRMVTEEEIQ--- 448
F + G+ V E + S++ + E + +
Sbjct: 357 NNNPDIEMEQFYRIATCHSSDTNPAKDDRCLQGIDVKDFELSTKASMNCLCIEADKREKK 416
Query: 449 ----FYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVT-AEKDFVLVPQM 503
+ KS RG NW+RN NW+W + GR +LIPAL+VT + VP +
Sbjct: 417 QLGGHHRSTKSKSKSRGA-NWFRNNAANWEWNRRLNGRMLLIPALVVTSGQGSPKDVPDV 475
Query: 504 SQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWL 542
S+ ++ WIP ++ H+ C T ++ +E+N+IL KWL
Sbjct: 476 SE-LKKWIPEVEHSHVSGCEIKTDRERSSELNRILRKWL 513
>emb|CAH91370.1| hypothetical protein [Pongo abelii]
Length = 372
Score = 455 bits (1172), Expect = e-126, Method: Composition-based stats.
Identities = 310/351 (88%), Positives = 316/351 (90%), Gaps = 3/351 (0%)
Query: 205 DTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHGYVTVKPRVRLHFVELGSGPAVCLC 264
T+ AL + P M +P VRLHFVELGSGPAVCLC
Sbjct: 25 RTEEALALPRGLLNDAFQKG---GPEGATTRLMRGEITLSQPGVRLHFVELGSGPAVCLC 81
Query: 265 HGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKL 324
HGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKL
Sbjct: 82 HGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESSAPPEIEEYCMEVLCKEMVTFLDKL 141
Query: 325 GLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNMSPLESIKANPVFDYQ 384
GLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPN+SPLESIKANPVFDYQ
Sbjct: 142 GLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNTPFIPANPNVSPLESIKANPVFDYQ 201
Query: 385 LYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVNSPEEPSLSRMVTE 444
LYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFV+SPEEPSLSRMVTE
Sbjct: 202 LYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMHKVCEAGGLFVSSPEEPSLSRMVTE 261
Query: 445 EEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMS 504
EEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMS
Sbjct: 262 EEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMS 321
Query: 505 QHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPPVVSKM 555
+HMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNP VVSKM
Sbjct: 322 KHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIKWLDSDARNPLVVSKM 372
Score = 97.5 bits (242), Expect = 3e-18, Method: Composition-based stats.
Identities = 82/182 (45%), Positives = 96/182 (52%), Gaps = 34/182 (18%)
Query: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL 60
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLM+GEITL
Sbjct: 1 MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMRGEITL 60
Query: 61 SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA 120
SQ P + + + VCL F R + A G+
Sbjct: 61 SQ--PGVRLHFVELGSGPAVCLCHGFPESWYSW---------RYQIPALAQ---AGYR-- 104
Query: 121 ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV 180
L + G + E++ E C + K ++ F LD L S+
Sbjct: 105 -----VLAMDMKGYGESSAPPEIE-------EYCMEVLCK---EMVTF-LDKLGL--SQA 146
Query: 181 VF 182
VF
Sbjct: 147 VF 148
>gb|EEJ94100.1| predicted hydrolase or acyltransferase of alpha/beta superfamily
[Thermomonospora curvata DSM 43183]
Length = 350
Score = 386 bits (991), Expect = e-105, Method: Composition-based stats.
Identities = 112/316 (35%), Positives = 170/316 (53%), Gaps = 7/316 (2%)
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
++++H + V + +H E GSGP V L HGFPE WYSWR+Q+ ALA+AG+ +A D
Sbjct: 34 MAEITHRTIEVN-GLNMHVAEAGSGPLVVLLHGFPECWYSWRHQLTALAEAGFHAVAPDQ 92
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
+GY + P + EY + L ++V + LG +AV +GHDWG + W+ A F P+ VR
Sbjct: 93 RGYARTGGPQRVAEYSILHLVGDVVALIAALGEERAVVVGHDWGAPVAWHTAQFRPDLVR 152
Query: 354 AVASLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKS-LFRAS 412
V L+ P + Y + FQEP EA E++++ TF+ L+ S
Sbjct: 153 GVVGLSVHPRPRTSRPPVAVMREQFGEGFYMVAFQEPKRPEAAFERDVADTFRRTLYALS 212
Query: 413 DESVLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERN 472
++ + V E G P L +TE++I Y +F SGF GPLNWYRN++RN
Sbjct: 213 GDAPGMLPVVPEGGSFLDVCPAPERLPGWLTEDDIAVYAAEFAASGFTGPLNWYRNLDRN 272
Query: 473 WKWACKSLGRKILIPALMVTAEKDFVL-VPQMSQ---HMEDWIPHLK-RGHIEDCGHWTQ 527
W+ I PAL + E+D VL P + + + +++P L+ + CGHWTQ
Sbjct: 273 WELTAAWHRAPITPPALYIAGERDMVLAGPGVKERLSRLREFVPDLRDIVLLPGCGHWTQ 332
Query: 528 MDKPTEVNQILIKWLD 543
++P EVN+ L+ +L
Sbjct: 333 QERPREVNEALLAFLR 348
>ref|NP_771160.1| epoxide hydrolase [Bradyrhizobium japonicum USDA 110]
dbj|BAC49785.1| epoxide hydrolase [Bradyrhizobium japonicum USDA 110]
Length = 318
Score = 384 bits (988), Expect = e-105, Method: Composition-based stats.
Identities = 116/314 (36%), Positives = 171/314 (54%), Gaps = 6/314 (1%)
Query: 237 MSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGY 296
MS V + L E G GP V LCHG+PE YSWR+QIPALA AG+ V+A DM+GY
Sbjct: 1 MSSTRVIKANGIDLFIREAGQGPLVVLCHGWPELSYSWRHQIPALAAAGFHVVAPDMRGY 60
Query: 297 GESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVA 356
G+S+AP ++ Y + ++V + LG S+A+ +GHDWG + W+ ALF P+ AVA
Sbjct: 61 GQSAAPADVSAYSIFDTVGDIVGLVQALGESKAMVVGHDWGAPVAWHAALFRPDIFTAVA 120
Query: 357 SLNTPFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASD-ES 415
L+ P + Y YFQ PGVAE ELE++++RT + +
Sbjct: 121 GLSVPPPFRGRGKPLDLLRQGGVTNFYWQYFQVPGVAEVELERDVARTMRIVLGGRGLAD 180
Query: 416 VLSMHKVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKW 475
+ V E G ++ + L ++E ++ ++ + F+KSGFRG LNWYRN++RNW+
Sbjct: 181 PSAAMFVQEGKGFLGHATADEPLPDWLSEADLAYFTETFRKSGFRGGLNWYRNLDRNWEL 240
Query: 476 ACKSLGRKILIPALMVTAEKDFV----LVPQMSQHMEDWIPHLKRG-HIEDCGHWTQMDK 530
+I P+L + KD V + + +E +P+L R IE GHW Q ++
Sbjct: 241 TAPWQDAQIHQPSLFIAGSKDAVITGLIGAKRVNELERVLPNLTRKLIIEGAGHWVQQER 300
Query: 531 PTEVNQILIKWLDS 544
P EVN L+K+L
Sbjct: 301 PDEVNAALVKFLRE 314
>ref|YP_629896.1| putative epoxide hydrolase [Myxococcus xanthus DK 1622]
gb|ABF91519.1| putative epoxide hydrolase [Myxococcus xanthus DK 1622]
Length = 318
Score = 382 bits (982), Expect = e-104, Method: Composition-based stats.
Identities = 120/317 (37%), Positives = 170/317 (53%), Gaps = 8/317 (2%)
Query: 234 PSDMSHGYVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDM 293
+D++H V + LH E GSGP V L HG+PESWYSWR+Q+PALA AGY +A D+
Sbjct: 1 MADITHRTVKTN-GINLHLAEAGSGPLVLLLHGWPESWYSWRHQLPALAAAGYHAVAPDV 59
Query: 294 KGYGESSAPPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR 353
+GYG+S P IE Y M+ L + V LD LG A+ IGHDWG + W A +P+R R
Sbjct: 60 RGYGQSDKPEAIEAYSMKQLVGDAVGLLDALGERTAIVIGHDWGSAIAWNCAALHPDRFR 119
Query: 354 AVASLNTPFIPANPNMSPLESIKANP--VFDYQLYFQEPGVAEAELEQNLSRTFKSLFRA 411
AV ++ P + P M P++ + + Y LYFQEPGVAEAE E ++ RT +++
Sbjct: 120 AVVGMSVPHLGRAP-MPPMQLFQRMFGEKWFYILYFQEPGVAEAEFEADVPRTVRAILTG 178
Query: 412 SDESVLSMHKVCE---AGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRN 468
+ ++ V G +L +TE ++ ++ ++ SGFRG LN YRN
Sbjct: 179 TPGFDVTNPAVLAKKKGEGFLARLDVPETLPGWLTEADVAYFAKELAGSGFRGGLNRYRN 238
Query: 469 MERNWKWACKSLGRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHL-KRGHIEDCGHWTQ 527
M+R+W + I PAL + EKD V M+ +P+L I GHW Q
Sbjct: 239 MDRDWHELPELATAVISQPALYIVGEKDPVRAFSPVDPMKALVPNLADIHVIPGAGHWVQ 298
Query: 528 MDKPTEVNQILIKWLDS 544
+ EVN L+ +L
Sbjct: 299 QEHAAEVNAALLAFLKK 315
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.312 0.165 0.508
Lambda K H
0.267 0.0507 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,331,606,867
Number of Sequences: 6899187
Number of extensions: 502239179
Number of successful extensions: 1400877
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 29836
Number of HSP's successfully gapped in prelim test: 23777
Number of HSP's that attempted gapping in prelim test: 1285422
Number of HSP's gapped (non-prelim): 80508
length of query: 555
length of database: 2,350,152,223
effective HSP length: 139
effective length of query: 416
effective length of database: 1,391,165,230
effective search space: 578724735680
effective search space used: 578724735680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 82 (35.9 bits)