BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= ENSG00000133835__[Homo_sapiens]
(736 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_000405.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1492 0.0
ref|XP_001087837.1| PREDICTED: hydroxysteroid (17-beta) deh... 1442 0.0
ref|XP_517892.2| PREDICTED: hydroxysteroid (17-beta) dehydr... 1419 0.0
ref|XP_531860.2| PREDICTED: similar to Peroxisomal multifun... 1327 0.0
ref|XP_859341.1| PREDICTED: similar to Peroxisomal multifun... 1320 0.0
ref|XP_859306.1| PREDICTED: similar to Peroxisomal multifun... 1317 0.0
ref|NP_001075370.1| 17 beta-hydroxysteroid dehydrogenase ty... 1315 0.0
ref|NP_077368.2| hydroxysteroid (17-beta) dehydrogenase 4 [... 1306 0.0
ref|NP_032318.2| hydroxysteroid (17-beta) dehydrogenase 4 [... 1303 0.0
dbj|BAE36514.1| unnamed protein product [Mus musculus] 1303 0.0
gb|AAB09724.1| peroxisomal multifunctional enzyme type II 1299 0.0
dbj|BAE27744.1| unnamed protein product [Mus musculus] 1299 0.0
emb|CAA62015.1| 17beta-hydroxysteroid dehydrogenase IV [Mus... 1298 0.0
gb|AAH72472.1| Hsd17b4 protein [Rattus norvegicus] 1295 0.0
gb|AAI22585.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Bo... 1293 0.0
emb|CAA64427.1| multifunctional protein 2 [Rattus norvegicus] 1287 0.0
ref|NP_001007810.1| hydroxysteroid (17-beta) dehydrogenase ... 1286 0.0
gb|EDL09934.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 1279 0.0
emb|CAA73945.1| mutifunctional protein2 [Cavia porcellus] 1270 0.0
ref|NP_999471.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1268 0.0
gb|EDM14436.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 1250 0.0
gb|EAW48910.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 1212 0.0
ref|XP_001088200.1| PREDICTED: hydroxysteroid (17-beta) deh... 1179 0.0
ref|XP_001378211.1| PREDICTED: similar to 17beta-hydroxyste... 1164 0.0
ref|XP_859266.1| PREDICTED: similar to Peroxisomal multifun... 1090 0.0
ref|NP_990274.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1085 0.0
ref|NP_001027490.1| hypothetical protein LOC613082 [Xenopus... 1085 0.0
ref|NP_001086063.1| MGC81885 protein [Xenopus laevis] >gi|4... 1072 0.0
ref|XP_001512505.1| PREDICTED: similar to 17beta-hydroxyste... 1069 0.0
dbj|BAF74749.1| hydroxysteroid (17-beta) dehydrogenase 4 [F... 1061 0.0
ref|NP_956430.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1030 0.0
gb|AAK27967.1|AF241285_1 17-beta-hydroxysteroid dehydrogena... 1030 0.0
gb|AAH65945.1| Hsd17b4 protein [Danio rerio] 1026 0.0
gb|EDM14435.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 987 0.0
dbj|BAD51963.1| 17-beta hydroxysteroid dehydrogenase 4 [Mac... 954 0.0
dbj|BAD92169.1| hydroxysteroid (17-beta) dehydrogenase 4 va... 943 0.0
ref|XP_001087962.1| PREDICTED: hydroxysteroid (17-beta) deh... 924 0.0
emb|CAG09600.1| unnamed protein product [Tetraodon nigrovir... 909 0.0
ref|XP_001624936.1| predicted protein [Nematostella vectens... 846 0.0
ref|XP_786662.2| PREDICTED: similar to 17-beta-hydroxystero... 738 0.0
ref|XP_974784.1| PREDICTED: similar to Peroxisomal multifun... 736 0.0
ref|XP_001652466.1| estradiol 17 beta-dehydrogenase [Aedes ... 729 0.0
ref|XP_001843060.1| peroxisomal multifunctional enzyme type... 725 0.0
ref|XP_001606624.1| PREDICTED: similar to estradiol 17 beta... 723 0.0
ref|XP_314766.4| AGAP008667-PA [Anopheles gambiae str. PEST... 707 0.0
ref|XP_393475.2| PREDICTED: similar to Peroxisomal multifun... 707 0.0
ref|XP_001743502.1| predicted protein [Monosiga brevicollis... 695 0.0
emb|CAB55552.1| Fox2 protein [Glomus mosseae] 676 0.0
ref|NP_573109.1| CG3415 CG3415-PA [Drosophila melanogaster]... 619 e-175
pdb|1ZBQ|A Chain A, Crystal Structure Of Human 17-Beta-Hydr... 617 e-174
pdb|1S9C|A Chain A, Crystal Structure Analysis Of The 2-Eno... 610 e-172
ref|XP_001355058.1| GA17436-PA [Drosophila pseudoobscura] >... 601 e-170
dbj|BAE90061.1| unnamed protein product [Macaca fascicularis] 595 e-168
pdb|1GZ6|A Chain A, (3r)-Hydroxyacyl-Coa Dehydrogenase Frag... 568 e-160
gb|EDL09933.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 556 e-156
ref|XP_369316.1| peroxisomal hydratase-dehydrogenase-epimer... 536 e-150
ref|XP_962039.1| peroxisomal hydratase-dehydrogenase-epimer... 525 e-147
ref|XP_001536930.1| hypothetical protein HCAG_08039 [Ajello... 522 e-146
ref|XP_001223046.1| peroxisomal hydratase-dehydrogenase-epi... 521 e-145
ref|XP_001906707.1| unnamed protein product [Podospora anse... 516 e-144
ref|XP_389819.1| FOX2_NEUCR Peroxisomal hydratase-dehydroge... 513 e-143
gb|EDU44349.1| peroxisomal multifunctional enzyme type 2 [P... 511 e-143
gb|EEH40042.1| peroxisomal multifunctional enzyme [Paracocc... 510 e-142
gb|EEH44993.1| peroxisomal multifunctional enzyme [Paracocc... 509 e-142
ref|XP_001262415.1| peroxisomal multifunctional beta-oxidat... 507 e-141
ref|XP_746577.1| peroxisomal multifunctional beta-oxidation... 507 e-141
ref|XP_001253030.1| PREDICTED: similar to Multifunctional p... 506 e-141
ref|XP_503980.1| hypothetical protein [Yarrowia lipolytica]... 506 e-141
pdb|2CDH|S Chain S, Architecture Of The Thermomyces Lanugin... 504 e-140
ref|XP_001241529.1| hypothetical protein CIMG_08692 [Coccid... 504 e-140
ref|XP_001400728.1| hypothetical protein An14g00990 [Asperg... 504 e-140
prf||2018258A 17beta-estradiol dehydrogenase 503 e-140
ref|XP_001803860.1| hypothetical protein SNOG_13654 [Phaeos... 502 e-140
ref|XP_001545846.1| hypothetical protein BC1G_15684 [Botryo... 498 e-138
ref|XP_001825975.1| hypothetical protein [Aspergillus oryza... 495 e-138
ref|XP_001589313.1| hypothetical protein SS1G_09947 [Sclero... 495 e-138
ref|XP_001274833.1| peroxisomal multifunctional beta-oxidat... 489 e-136
ref|XP_756297.1| hypothetical protein UM00150.1 [Ustilago m... 486 e-135
ref|XP_001211399.1| acetoacetyl-CoA reductase [Aspergillus ... 484 e-134
ref|XP_001880676.1| multifunctional beta-oxidation protein ... 478 e-133
ref|XP_571589.1| peroxisomal hydratase-dehydrogenase-epimer... 473 e-131
ref|XP_664715.1| hypothetical protein AN7111.2 [Aspergillus... 466 e-129
ref|XP_001729772.1| hypothetical protein MGL_3316 [Malassez... 461 e-128
ref|XP_001383009.1| hypothetical protein PICST_54590 [Pichi... 413 e-113
ref|XP_456704.1| hypothetical protein DEHA0A08778g [Debaryo... 410 e-112
gb|ABI95866.1| 17-beta-hydroxysteroid dehydrogenase type 4 ... 405 e-110
ref|XP_001484143.1| hypothetical protein PGUG_03524 [Pichia... 404 e-110
ref|XP_001642757.1| hypothetical protein Kpol_348p3 [Vander... 403 e-110
ref|XP_710072.1| peroxisomal hydratase-dehydrogenase-epimer... 395 e-108
ref|XP_001527383.1| peroxisomal hydratase-dehydrogenase-epi... 394 e-107
ref|XP_454574.1| unnamed protein product [Kluyveromyces lac... 389 e-106
sp|P22414|FOX2_CANTR Peroxisomal hydratase-dehydrogenase-ep... 388 e-106
gb|AAA62847.1| hydratase-dehydrogenase-epimerase 385 e-105
ref|XP_448864.1| unnamed protein product [Candida glabrata]... 372 e-101
ref|NP_986606.1| AGL060Wp [Ashbya gossypii ATCC 10895] >gi|... 371 e-100
ref|XP_635235.1| hypothetical protein DDB_0201628 [Dictyost... 365 8e-99
gb|AAG01113.1| 17-beta-hydroxysteroid dehydrogenase type 4 ... 364 2e-98
ref|YP_457088.1| probable short-chain dehydrogenase [Erythr... 363 3e-98
ref|YP_001171638.1| probable short-chain dehydrogenase [Pse... 358 8e-97
ref|YP_346635.1| Short-chain dehydrogenase/reductase SDR [P... 358 1e-96
ref|YP_001188762.1| short-chain dehydrogenase/reductase SDR... 358 1e-96
ref|NP_012934.1| Multifunctional enzyme of the peroxisomal ... 356 3e-96
gb|AAS21352.1| 17-beta-hydroxysteroid dehydrogenase type IV... 356 5e-96
gb|EDN59917.1| multifunctional beta-oxidation protein [Sacc... 355 5e-96
ref|NP_252117.1| probable short-chain dehydrogenases [Pseud... 355 6e-96
ref|YP_258092.1| oxidoreductase, short chain dehydrogenase/... 355 8e-96
gb|AAT51203.1| PA3427 [synthetic construct] 355 8e-96
ref|YP_001347083.1| probable short-chain dehydrogenase [Pse... 353 2e-95
ref|ZP_01615241.1| Short-chain dehydrogenase/reductase SDR ... 353 2e-95
ref|NP_791019.1| oxidoreductase, short chain dehydrogenase/... 351 1e-94
ref|YP_273346.1| oxidoreductase, short chain dehydrogenase/... 347 3e-93
ref|YP_234119.1| Short-chain dehydrogenase/reductase SDR [P... 346 4e-93
ref|YP_610072.1| oxidoreductase, short chain dehydrogenase/... 344 1e-92
ref|YP_001670829.1| short-chain dehydrogenase/reductase SDR... 341 2e-91
ref|XP_001455301.1| hypothetical protein GSPATT00021528001 ... 340 2e-91
ref|XP_001457027.1| hypothetical protein GSPATT00022802001 ... 340 3e-91
ref|XP_001021425.1| acyl carrier protein reductase [Tetrahy... 338 8e-91
ref|NP_509146.1| DeHydrogenases, Short chain family member ... 338 9e-91
ref|XP_001676977.1| Hypothetical protein CBG10899 [Caenorha... 338 1e-90
ref|YP_001747689.1| short-chain dehydrogenase/reductase SDR... 337 2e-90
gb|ABY59724.1| D-bifunctional protein [Toxoplasma gondii] 325 1e-86
ref|YP_459035.1| oxidoreductase, short chain dehydrogenase/... 319 6e-85
ref|XP_001426526.1| hypothetical protein GSPATT00029759001 ... 313 3e-83
gb|EAW92030.1| hCG1779566, isoform CRA_a [Homo sapiens] 300 3e-79
ref|XP_001836311.1| hypothetical protein CC1G_06396 [Coprin... 299 6e-79
ref|ZP_02131456.1| short-chain dehydrogenase/reductase SDR ... 295 8e-78
emb|CAP31946.1| C. briggsae CBR-MAOC-1 protein [Caenorhabdi... 293 3e-77
pdb|2ET6|A Chain A, (3r)-Hydroxyacyl-Coa Dehydrogenase Doma... 291 9e-77
ref|ZP_02134354.1| short-chain dehydrogenase/reductase SDR ... 291 2e-76
ref|YP_001529431.1| short-chain dehydrogenase/reductase SDR... 291 2e-76
ref|NP_495494.1| E04F6.3 [Caenorhabditis elegans] >gi|86133... 291 2e-76
ref|YP_001529430.1| short-chain dehydrogenase/reductase SDR... 288 1e-75
gb|EDL09935.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 283 4e-74
gb|EEJ95553.1| dehydrogenase of unknown specificity similar... 281 2e-73
ref|NP_334566.1| oxidoreductase, short-chain dehydrogenase/... 279 5e-73
ref|NP_214662.1| PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/RE... 279 6e-73
ref|XP_001440682.1| hypothetical protein GSPATT00009600001 ... 278 1e-72
gb|EAW92031.1| hCG1779566, isoform CRA_b [Homo sapiens] 278 2e-72
ref|YP_884263.1| peroxisomal multifunctional enzyme type 2 ... 276 4e-72
gb|AAT47756.1| probable short-chain dehydrogenase [Mycobact... 276 5e-72
ref|ZP_02131455.1| short-chain dehydrogenase/reductase SDR ... 275 9e-72
ref|XP_001433168.1| hypothetical protein GSPATT00006270001 ... 275 1e-71
ref|NP_962501.1| hypothetical protein MAP3567 [Mycobacteriu... 275 1e-71
ref|YP_001412346.1| short-chain dehydrogenase/reductase SDR... 273 3e-71
ref|XP_001123292.1| PREDICTED: similar to CG3415-PA, partia... 270 4e-70
ref|YP_001705327.1| Putative short-chain dehydrogenase/redu... 267 3e-69
ref|YP_908150.1| short-chain type dehydrogenase/reductase [... 267 3e-69
ref|YP_884512.1| peroxisomal hydratase-dehydrogenase-epimer... 266 4e-69
ref|YP_950963.1| short-chain dehydrogenase/reductase SDR [M... 265 1e-68
ref|YP_001132014.1| short-chain dehydrogenase/reductase SDR... 265 1e-68
ref|YP_001068385.1| short-chain dehydrogenase/reductase SDR... 264 3e-68
ref|YP_637269.1| short-chain dehydrogenase/reductase SDR [M... 263 3e-68
ref|XP_001900411.1| oxidoreductase, short chain dehydrogena... 260 3e-67
ref|YP_458654.1| possible 3-oxo-(acyl) acyl carrier protein... 253 5e-65
ref|YP_761498.1| oxidoreductase, short chain dehydrogenase/... 251 1e-64
ref|YP_001888840.1| short-chain dehydrogenase/reductase SDR... 250 3e-64
ref|XP_001896267.1| maoC like domain containing protein [Br... 250 3e-64
ref|YP_615585.1| short-chain dehydrogenase/reductase SDR [S... 249 4e-64
ref|YP_750748.1| short-chain dehydrogenase/reductase SDR [S... 249 5e-64
gb|EEJ94366.1| dehydrogenase of unknown specificity similar... 248 1e-63
ref|YP_884196.1| peroxisomal hydratase-dehydrogenase-epimer... 248 1e-63
ref|ZP_01864417.1| possible 3-oxo-(acyl) acyl carrier prote... 248 1e-63
ref|YP_001563493.1| short-chain dehydrogenase/reductase SDR... 248 1e-63
ref|XP_001435177.1| hypothetical protein GSPATT00036560001 ... 248 1e-63
ref|ZP_00952848.1| possible 3-oxo-(acyl) acyl carrier prote... 247 3e-63
ref|ZP_01040272.1| Short-chain dehydrogenase/reductase SDR ... 245 1e-62
ref|YP_986758.1| short-chain dehydrogenase/reductase SDR [A... 244 1e-62
ref|ZP_01519585.1| short-chain dehydrogenase/reductase SDR ... 244 1e-62
ref|YP_001508763.1| short-chain dehydrogenase/reductase SDR... 244 3e-62
ref|YP_692674.1| oxidoreductase [Alcanivorax borkumensis SK... 243 4e-62
gb|ABG34305.1| 17beta hydroxysteroid dehydrogenase type 4 [... 243 6e-62
ref|YP_756878.1| short-chain dehydrogenase/reductase SDR [M... 242 7e-62
ref|XP_001836310.1| hypothetical protein CC1G_06395 [Coprin... 242 8e-62
prf||2018258B 17beta-estradiol dehydrogenase 242 1e-61
ref|ZP_01616123.1| oxidoreductase, short chain dehydrogenas... 241 1e-61
ref|ZP_01223710.1| oxidoreductase, short chain dehydrogenas... 241 2e-61
ref|ZP_01103376.1| Short-chain dehydrogenase/reductase SDR ... 239 4e-61
pdb|1IKT|A Chain A, Liganded Sterol Carrier Protein Type 2 ... 239 5e-61
ref|YP_001205176.1| putative 3-oxo-(acyl) acyl carrier prot... 234 3e-59
ref|YP_486812.1| Short-chain dehydrogenase/reductase SDR [R... 233 3e-59
ref|YP_497943.1| short-chain dehydrogenase/reductase SDR [N... 233 4e-59
ref|YP_167200.1| oxidoreductase, short chain dehydrogenase/... 232 1e-58
ref|YP_001239580.1| putative 3-oxo-(acyl) acyl carrier prot... 232 1e-58
ref|YP_001684966.1| short-chain dehydrogenase/reductase SDR... 231 1e-58
ref|YP_569386.1| short-chain dehydrogenase/reductase SDR [R... 231 2e-58
ref|NP_420896.1| 3-oxoacyl-(acyl-carrier-protein) reductase... 230 3e-58
ref|ZP_02298781.1| short-chain dehydrogenase/reductase SDR ... 230 4e-58
ref|YP_367244.1| Short-chain dehydrogenase/reductase SDR [B... 229 5e-58
ref|NP_947531.1| possible 3-oxo-(acyl) acyl carrier protein... 229 8e-58
ref|ZP_02887245.1| short-chain dehydrogenase/reductase SDR ... 227 2e-57
ref|NP_770600.1| probable short-chain dehydrogenase [Bradyr... 227 3e-57
ref|ZP_01626410.1| possible 3-oxo-(acyl) acyl carrier prote... 226 6e-57
ref|ZP_00998756.1| oxidoreductase, short chain dehydrogenas... 224 2e-56
ref|ZP_01012181.1| oxidoreductase, short chain dehydrogenas... 224 2e-56
ref|YP_781309.1| short-chain dehydrogenase/reductase SDR [R... 224 3e-56
ref|NP_177742.2| maoC-like dehydratase domain-containing pr... 224 3e-56
ref|ZP_00963728.1| oxidoreductase, short chain dehydrogenas... 223 5e-56
ref|ZP_00956517.1| oxidoreductase, short chain dehydrogenas... 223 5e-56
ref|ZP_01225010.1| oxidoreductase, short chain dehydrogenas... 220 4e-55
ref|YP_641564.1| short-chain dehydrogenase/reductase SDR [M... 219 5e-55
ref|ZP_01618277.1| probable short-chain dehydrogenase [mari... 219 9e-55
ref|YP_532949.1| short-chain dehydrogenase/reductase SDR [R... 218 2e-54
ref|NP_962444.1| hypothetical protein MAP3510 [Mycobacteriu... 216 6e-54
ref|ZP_01449443.1| oxidoreductase, short chain dehydrogenas... 216 8e-54
ref|NP_773012.1| probable short-chain dehydrogenase [Bradyr... 215 1e-53
ref|YP_001481079.1| short-chain dehydrogenase/reductase SDR... 215 1e-53
ref|YP_002768427.1| oxidoreductase [Rhodococcus erythropoli... 213 4e-53
ref|YP_001133058.1| short-chain dehydrogenase/reductase SDR... 213 4e-53
ref|NP_001063833.1| Os09g0544900 [Oryza sativa (japonica cu... 211 3e-52
ref|YP_001508000.1| short-chain dehydrogenase/reductase SDR... 210 4e-52
ref|YP_001848632.1| short-chain type dehydrogenase/reductas... 209 9e-52
ref|YP_889858.1| oxidoreductase, short chain dehydrogenase/... 208 1e-51
ref|YP_908194.1| short-chain type dehydrogenase/reductase [... 207 3e-51
ref|ZP_01016095.1| probable short-chain dehydrogenase [Parv... 205 1e-50
ref|NP_249714.1| probable short-chain dehydrogenase [Pseudo... 205 1e-50
gb|AAT51173.1| PA1023 [synthetic construct] 205 1e-50
ref|ZP_00964987.1| COG1028: Dehydrogenases with different s... 204 2e-50
ref|YP_712724.1| putative short-chain dehydrogenase; putati... 204 2e-50
ref|YP_639699.1| short-chain dehydrogenase/reductase SDR [M... 204 2e-50
ref|YP_001632529.1| probable short-chain type dehydrogenase... 204 2e-50
ref|YP_884321.1| oxidoreductase, short chain dehydrogenase/... 203 3e-50
ref|YP_792247.1| probable short-chain dehydrogenase [Pseudo... 203 5e-50
ref|YP_001685634.1| short-chain dehydrogenase/reductase SDR... 201 1e-49
ref|YP_001135414.1| short-chain dehydrogenase/reductase SDR... 201 2e-49
ref|ZP_02299795.1| short-chain dehydrogenase/reductase SDR ... 201 2e-49
ref|NP_771972.1| probable short-chain dehydrogenase [Bradyr... 201 2e-49
ref|YP_001206283.1| putative short-chain dehydrogenase/redu... 199 8e-49
ref|NP_948530.1| putative short-chain dehydrogenase [Rhodop... 199 9e-49
ref|XP_001455573.1| hypothetical protein GSPATT00003144001 ... 199 1e-48
ref|YP_001349713.1| oxidoreductase, short chain dehydrogena... 198 1e-48
ref|XP_001425848.1| hypothetical protein GSPATT00004822001 ... 197 2e-48
ref|XP_642412.1| hypothetical protein DDB_0214811 [Dictyost... 197 2e-48
ref|YP_001260871.1| short-chain dehydrogenase/reductase SDR... 197 3e-48
ref|YP_955738.1| short-chain dehydrogenase/reductase SDR [M... 196 5e-48
ref|YP_997152.1| short-chain dehydrogenase/reductase SDR [V... 196 8e-48
ref|XP_001763373.1| predicted protein [Physcomitrella paten... 195 9e-48
ref|YP_001240913.1| putative short-chain dehydrogenase/redu... 195 9e-48
ref|YP_001413496.1| short-chain dehydrogenase/reductase SDR... 195 9e-48
ref|YP_001774493.1| short-chain dehydrogenase/reductase SDR... 195 1e-47
ref|YP_001413075.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-b... 195 1e-47
ref|XP_001020820.1| MaoC like domain containing protein [Te... 194 2e-47
ref|YP_001701360.1| Probable short-chain dehydrogenase/redu... 194 2e-47
ref|ZP_01227959.1| putative short chain dehydrogenase famil... 194 3e-47
ref|YP_726617.1| short chain dehydrogenase [Ralstonia eutro... 193 5e-47
ref|YP_001238963.1| Putative short-chain dehydrogenase [Bra... 192 8e-47
ref|YP_569014.1| short-chain dehydrogenase/reductase SDR [R... 192 9e-47
ref|YP_298036.1| Short-chain dehydrogenase/reductase SDR [R... 192 1e-46
ref|NP_769597.1| putative short-chain dehydrogenase [Bradyr... 191 1e-46
ref|ZP_02300115.1| short-chain dehydrogenase/reductase SDR ... 191 2e-46
ref|YP_001684866.1| short-chain dehydrogenase/reductase SDR... 191 3e-46
ref|YP_713998.1| putative oxidoreductase [Frankia alni ACN1... 190 3e-46
ref|NP_947120.1| putative dehydrogenase [Rhodopseudomonas p... 190 3e-46
ref|YP_780721.1| short-chain dehydrogenase/reductase SDR [R... 190 4e-46
ref|ZP_01037648.1| putative short-chain dehydrogenase [Rose... 189 6e-46
ref|YP_487195.1| Short-chain dehydrogenase/reductase SDR [R... 189 7e-46
ref|ZP_01000038.1| probable short-chain dehydrogenase [Ocea... 189 1e-45
ref|NP_771973.1| putative dehydrogenase [Bradyrhizobium jap... 188 1e-45
ref|YP_001264115.1| short-chain dehydrogenase/reductase SDR... 188 1e-45
ref|YP_001561227.1| short-chain dehydrogenase/reductase SDR... 187 2e-45
ref|YP_001204639.1| Putative short-chain dehydrogenase [Bra... 187 2e-45
ref|YP_001411770.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-b... 187 2e-45
ref|ZP_02190724.1| MaoC-like dehydratase [alpha proteobacte... 187 2e-45
ref|YP_728558.1| Dehydrogenase [Ralstonia eutropha H16] >gi... 187 3e-45
ref|YP_704598.1| short chain dehydrogenase [Rhodococcus sp.... 187 4e-45
ref|YP_001132762.1| short chain dehydrogenase [Mycobacteriu... 187 4e-45
ref|YP_001166145.1| short-chain dehydrogenase/reductase SDR... 186 4e-45
ref|ZP_01520457.1| short-chain dehydrogenase/reductase SDR ... 186 7e-45
ref|YP_890225.1| short chain dehydrogenase [Mycobacterium s... 186 8e-45
ref|YP_999339.1| short-chain dehydrogenase/reductase SDR [V... 185 1e-44
ref|ZP_03879616.1| acyl dehydratase [Haliangium ochraceum D... 185 1e-44
ref|ZP_01442178.1| probable short-chain dehydrogenase [Rose... 184 2e-44
ref|YP_705752.1| possible MaoC family dehydratase [Rhodococ... 184 2e-44
ref|YP_641841.1| short chain dehydrogenase [Mycobacterium s... 184 2e-44
ref|YP_984451.1| short-chain dehydrogenase/reductase SDR [A... 184 3e-44
ref|NP_891300.1| putative (R)-specific enoyl-CoA hydratase ... 184 3e-44
ref|YP_002781944.1| putative oxidoreductase [Rhodococcus op... 183 4e-44
gb|EEJ96228.1| dehydrogenase of unknown specificity similar... 183 4e-44
ref|YP_552606.1| Short-chain dehydrogenase/reductase SDR [B... 183 4e-44
ref|YP_293456.1| Short-chain dehydrogenase/reductase SDR [R... 183 4e-44
ref|NP_946764.1| MaoC-like dehydratase [Rhodopseudomonas pa... 183 5e-44
ref|ZP_01000112.1| MaoC-like dehydratase [Oceanicola batsen... 182 6e-44
ref|YP_001853295.1| short-chain type dehydrogenase/reductas... 182 7e-44
ref|YP_002764368.1| oxidoreductase [Rhodococcus erythropoli... 182 9e-44
ref|NP_338197.1| short chain dehydrogenase [Mycobacterium t... 182 1e-43
ref|NP_218065.1| short chain dehydrogenase [Mycobacterium t... 181 1e-43
ref|YP_907626.1| short chain dehydrogenase [Mycobacterium u... 181 1e-43
ref|YP_119600.1| putative short chain dehydrogenase [Nocard... 181 1e-43
ref|YP_001159499.1| MaoC domain protein dehydratase [Salini... 181 1e-43
ref|YP_552038.1| short-chain dehydrogenase/reductase SDR [P... 181 2e-43
ref|NP_857217.1| short chain dehydrogenase [Mycobacterium b... 181 2e-43
ref|ZP_01037658.1| MaoC-like dehydratase [Roseovarius sp. 2... 181 2e-43
ref|YP_001613532.1| Putative short-chain dehydrogenases [So... 181 2e-43
ref|YP_956041.1| short chain dehydrogenase [Mycobacterium v... 181 3e-43
ref|YP_116721.1| short chain dehydrogenase [Nocardia farcin... 180 3e-43
ref|NP_959452.1| short chain dehydrogenase [Mycobacterium a... 180 4e-43
ref|YP_879892.1| short chain dehydrogenase [Mycobacterium a... 180 4e-43
ref|YP_001628977.1| probable short-chain type dehydrogenase... 179 8e-43
ref|YP_001084848.1| Short-chain dehydrogenase/reductase SDR... 179 1e-42
ref|YP_533245.1| MaoC-like dehydratase [Rhodopseudomonas pa... 178 2e-42
ref|YP_002779673.1| putative oxidoreductase [Rhodococcus op... 177 2e-42
>ref|NP_000405.1| hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
sp|P51659|DHB4_HUMAN Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: 3-hydroxyacyl-CoA
dehydrogenase ;
3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase ]
emb|CAA60643.1| 17beta-hydroxysteroid dehydrogenase [Homo sapiens]
gb|AAD08652.1| 17-beta-hydroxysteroid dehydrogenase IV [Homo sapiens]
gb|AAH03098.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
gb|EAW48911.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Homo
sapiens]
gb|ABM82792.1| hydroxysteroid (17-beta) dehydrogenase 4 [synthetic construct]
gb|ABM85981.1| hydroxysteroid (17-beta) dehydrogenase 4 [synthetic construct]
Length = 736
Score = 1492 bits (3863), Expect = 0.0, Method: Composition-based stats.
Identities = 736/736 (100%), Positives = 736/736 (100%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
Sbjct: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
Sbjct: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
Sbjct: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI
Sbjct: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
Sbjct: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 721 MLSQKLQMILKDYAKL 736
>ref|XP_001087837.1| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 isoform 1
[Macaca mulatta]
Length = 734
Score = 1442 bits (3733), Expect = 0.0, Method: Composition-based stats.
Identities = 716/736 (97%), Positives = 725/736 (98%), Gaps = 2/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVA+YDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 61 EIRRRGGKAVASYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG VSANHTS ATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
Sbjct: 301 KIDSEG-VSANHTSHATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGSSDFSCLPTFGVIIGQKS+MGGGLAEIPGLSINFAKV+ GE ++ KPL R
Sbjct: 360 LKFVYEGSSDFSCLPTFGVIIGQKSLMGGGLAEIPGLSINFAKVI-GEPSMKAEKPLKRV 418
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
Sbjct: 419 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 478
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 479 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 538
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
ARR+LQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 539 ARRILQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 598
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDLAPTS TSAKTPSEGGKLQST VFEEIGRRLKD+GPEVVKKVNAVFEWHITKGGNI
Sbjct: 599 AYVDLAPTSDTSAKTPSEGGKLQSTLVFEEIGRRLKDVGPEVVKKVNAVFEWHITKGGNI 658
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
Sbjct: 659 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 718
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 719 MLSQKLQMILKDYAKL 734
>ref|XP_517892.2| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 [Pan
troglodytes]
Length = 712
Score = 1419 bits (3673), Expect = 0.0, Method: Composition-based stats.
Identities = 695/702 (99%), Positives = 697/702 (99%)
Query: 35 LVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRID 94
V +NDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRID
Sbjct: 11 FVSMNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRID 70
Query: 95 VVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASG 154
VVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASG
Sbjct: 71 VVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASG 130
Query: 155 IYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALK 214
IYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALK
Sbjct: 131 IYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALK 190
Query: 215 PEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWK 274
PEYVAPLVLWLCH+SCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWK
Sbjct: 191 PEYVAPLVLWLCHDSCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWK 250
Query: 275 KICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPP 334
KICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPP
Sbjct: 251 KICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPP 310
Query: 335 FSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI 394
FSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI
Sbjct: 311 FSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI 370
Query: 395 PGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELI 454
PGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELI
Sbjct: 371 PGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELI 430
Query: 455 CHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPL 514
CHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPL
Sbjct: 431 CHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPL 490
Query: 515 HIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQ 574
HIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQ
Sbjct: 491 HIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQ 550
Query: 575 TEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRR 634
TEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTS TSAKTPSEG KLQST VFEEIGRR
Sbjct: 551 TEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSDTSAKTPSEGEKLQSTLVFEEIGRR 610
Query: 635 LKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDED 694
LKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDED
Sbjct: 611 LKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDED 670
Query: 695 FMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
FMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 671 FMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 712
>ref|XP_531860.2| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 2 [Canis familiaris]
Length = 737
Score = 1327 bits (3434), Expect = 0.0, Method: Composition-based stats.
Identities = 643/737 (87%), Positives = 683/737 (92%), Gaps = 1/737 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAA-DKVV 59
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG+GKGS AA DKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+ IDS+GGVS NHTS A STATS FAGAIG K PPFS AYTELE IMYALGVGAS+K+PK
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPK 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
D+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPR
Sbjct: 361 DMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPR 420
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
AG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDKVK
Sbjct: 421 AGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVK 480
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGF
Sbjct: 481 ATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGF 540
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVIS
Sbjct: 541 SARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVIS 600
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
NAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGN
Sbjct: 601 NAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGN 660
Query: 660 IGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGN 719
I AKWTIDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKARGN
Sbjct: 661 IAAKWTIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKARGN 720
Query: 720 IMLSQKLQMILKDYAKL 736
IMLSQKLQMILKDYAKL
Sbjct: 721 IMLSQKLQMILKDYAKL 737
>ref|XP_859341.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 5 [Canis familiaris]
Length = 739
Score = 1320 bits (3415), Expect = 0.0, Method: Composition-based stats.
Identities = 642/739 (86%), Positives = 682/739 (92%), Gaps = 3/739 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAA-DKVV 59
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG+GKGS AA DKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVSANHTSRATSTATS--GFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
+ IDS+GGVS NHTS A STATS AGAIG K PPFS AYTELE IMYALGVGAS+K+
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEADMAGAIGHKFPPFSSAYTELETIMYALGVGASVKE 360
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPL 417
PKD+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPL
Sbjct: 361 PKDMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPL 420
Query: 418 PRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDK 477
PRAG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDK
Sbjct: 421 PRAGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDK 480
Query: 478 VKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTF 537
VK VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTF
Sbjct: 481 VKATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTF 540
Query: 538 GFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIV 597
GFSAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIV
Sbjct: 541 GFSARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIV 600
Query: 598 ISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKG 657
ISNAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKG
Sbjct: 601 ISNAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKG 660
Query: 658 GNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKAR 717
GNI AKWTIDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKAR
Sbjct: 661 GNIAAKWTIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKAR 720
Query: 718 GNIMLSQKLQMILKDYAKL 736
GNIMLSQKLQMILKDYAKL
Sbjct: 721 GNIMLSQKLQMILKDYAKL 739
>ref|XP_859306.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 4 [Canis familiaris]
Length = 753
Score = 1317 bits (3408), Expect = 0.0, Method: Composition-based stats.
Identities = 642/753 (85%), Positives = 683/753 (90%), Gaps = 17/753 (2%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAA-DKVV 59
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG+GKGS AA DKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+ IDS+GGVS NHTS A STATS FAGAIG K PPFS AYTELE IMYALGVGAS+K+PK
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPK 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
D+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPR
Sbjct: 361 DMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPR 420
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
AG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDKVK
Sbjct: 421 AGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVK 480
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGF
Sbjct: 481 ATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGF 540
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVIS
Sbjct: 541 SARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVIS 600
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
NAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGN
Sbjct: 601 NAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGN 660
Query: 660 IGAKWT----------------IDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKL 703
I AKW+ IDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKL
Sbjct: 661 IAAKWSNRVISFSISLFLLLTAIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKL 720
Query: 704 DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 721 DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 753
>ref|NP_001075370.1| 17 beta-hydroxysteroid dehydrogenase type 4 [Equus caballus]
gb|AAS77255.1| 17 beta-hydroxysteroid dehydrogenase type 4 [Equus caballus]
Length = 735
Score = 1315 bits (3404), Expect = 0.0, Method: Composition-based stats.
Identities = 637/736 (86%), Positives = 685/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRFDGRVVLVTGAG GLGRAYALAF ERGA VVVNDLGGD KGVGK SLAADKVVE
Sbjct: 1 MASQLRFDGRVVLVTGAGGGLGRAYALAFGERGASVVVNDLGGDMKGVGKSSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR RGGKAVA+YDSVE GEK+VKTALDAFGRIDVVVNNAGILRDRSF R+SDEDWDIIH
Sbjct: 61 EIRSRGGKAVASYDSVEAGEKIVKTALDAFGRIDVVVNNAGILRDRSFGRLSDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSASGIYGNFGQANYSAAKLGLLGL+N+LAI
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASGIYGNFGQANYSAAKLGLLGLSNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSR+TQTV PED+VEALKP+YVAPLVLWLCHESCEENG LFEVG
Sbjct: 181 EGKKNNIHCNTIAPQAGSRLTQTVFPEDVVEALKPDYVAPLVLWLCHESCEENGSLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGA+VRQ+N PMTPEAVKANWKKICDF + S PQ+IQESTG II ++S
Sbjct: 241 AGWIGKLRWERTLGALVRQRNQPMTPEAVKANWKKICDFGSVSNPQTIQESTGGIIGLVS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DS GGVS NHTS A STATSGF GAIGQKLP FS YTELEAIMYALGVGASIK+PKD
Sbjct: 301 KMDSNGGVSTNHTSHAASTATSGFVGAIGQKLPSFSSTYTELEAIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI QKSM+ G LA+IPGLS++FAKVLHGEQYLELYKPLPR
Sbjct: 361 MKFIYEGSSDFSCLPTFGVITAQKSML-GELAQIPGLSLDFAKVLHGEQYLELYKPLPRT 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCE VVAD+LDKGSGVVI++DVYSYS EL+C+NQFSLFLVGSGGFGGKRTSDK+KV
Sbjct: 420 GKLKCEGVVADILDKGSGVVILLDVYSYSGNELLCYNQFSLFLVGSGGFGGKRTSDKMKV 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDA+LTDTTSLNQAALYRLSGDWNPLHIDPNF+SLAGFDKPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAILTDTTSLNQAALYRLSGDWNPLHIDPNFSSLAGFDKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFAD+DVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVISN
Sbjct: 540 ARHVLQQFADHDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTS AKTPS+GG+LQST VFEEIGRRLKDIG +VVK VNAVFEWHIT+GGN
Sbjct: 600 AYVDLVPTSDMLAKTPSKGGELQSTLVFEEIGRRLKDIGHQVVKTVNAVFEWHITEGGNT 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
A WTIDLK+GSG+VYQGPA+G+ADTT+ LSDE FMEVV GKLDPQKAFFSG+LKA+GNI
Sbjct: 660 AATWTIDLKNGSGEVYQGPARGSADTTLTLSDEHFMEVVQGKLDPQKAFFSGKLKAKGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
M+SQKLQ ILKDYAKL
Sbjct: 720 MVSQKLQKILKDYAKL 735
>ref|NP_077368.2| hydroxysteroid (17-beta) dehydrogenase 4 [Rattus norvegicus]
sp|P97852|DHB4_RAT Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: 3-hydroxyacyl-CoA
dehydrogenase ;
3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase ]
gb|AAB49519.1| 17 beta-hydroxysteroid dehydrogenase type IV; HSD IV [Rattus sp.]
Length = 735
Score = 1306 bits (3380), Expect = 0.0, Method: Composition-based stats.
Identities = 643/736 (87%), Positives = 690/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG +S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>ref|NP_032318.2| hydroxysteroid (17-beta) dehydrogenase 4 [Mus musculus]
sp|P51660|DHB4_MOUSE Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: 3-hydroxyacyl-CoA
dehydrogenase ;
3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase ]
dbj|BAB23627.1| unnamed protein product [Mus musculus]
gb|AAH22175.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Mus musculus]
dbj|BAC40317.1| unnamed protein product [Mus musculus]
dbj|BAE40862.1| unnamed protein product [Mus musculus]
dbj|BAE39029.1| unnamed protein product [Mus musculus]
dbj|BAE39222.1| unnamed protein product [Mus musculus]
gb|EDL09936.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_d [Mus
musculus]
Length = 735
Score = 1303 bits (3372), Expect = 0.0, Method: Composition-based stats.
Identities = 635/736 (86%), Positives = 687/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG +S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>dbj|BAE36514.1| unnamed protein product [Mus musculus]
Length = 735
Score = 1303 bits (3372), Expect = 0.0, Method: Composition-based stats.
Identities = 635/736 (86%), Positives = 686/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG +S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTHTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>gb|AAB09724.1| peroxisomal multifunctional enzyme type II
Length = 735
Score = 1299 bits (3361), Expect = 0.0, Method: Composition-based stats.
Identities = 640/736 (86%), Positives = 687/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDS E GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSGEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIY NFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYSNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG +S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+ GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLTSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPDRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>dbj|BAE27744.1| unnamed protein product [Mus musculus]
Length = 735
Score = 1299 bits (3361), Expect = 0.0, Method: Composition-based stats.
Identities = 634/736 (86%), Positives = 686/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG +S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSG WNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGGWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>emb|CAA62015.1| 17beta-hydroxysteroid dehydrogenase IV [Mus musculus]
Length = 735
Score = 1298 bits (3358), Expect = 0.0, Method: Composition-based stats.
Identities = 633/736 (86%), Positives = 685/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTG G GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGPGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG +S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPL R+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLLRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>gb|AAH72472.1| Hsd17b4 protein [Rattus norvegicus]
Length = 751
Score = 1295 bits (3351), Expect = 0.0, Method: Composition-based stats.
Identities = 642/752 (85%), Positives = 689/752 (91%), Gaps = 17/752 (2%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG +S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKW----------------TIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLD 704
AKW IDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+
Sbjct: 660 AAKWMELTISFSVSSLLPANAIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLN 719
Query: 705 PQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
PQ AFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 720 PQNAFFSGRLKARGNIMLSQKLQMILKDYAKL 751
>gb|AAI22585.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Bos taurus]
Length = 736
Score = 1293 bits (3345), Expect = 0.0, Method: Composition-based stats.
Identities = 631/736 (85%), Positives = 680/736 (92%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRF+GRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDF GVGKGSLAADKVVE
Sbjct: 1 MASTLRFNGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFTGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVEEGEK+VKTALDAFGRID+V+NNAGILRDRSF+RISDEDWD I
Sbjct: 61 EIRRKGGKAVANYDSVEEGEKIVKTALDAFGRIDIVINNAGILRDRSFSRISDEDWDKIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSASGIYGNFGQANY AAKLGLLGL+N LA+
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASGIYGNFGQANYCAAKLGLLGLSNCLAV 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSRMTQ+++PEDLVEALKP+YVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRMTQSILPEDLVEALKPDYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LGA+VRQ+ PMTPEAVKANW KICDF+NA+KP+SIQES GSI+E L+
Sbjct: 241 AGWIGKLRWERSLGALVRQRTQPMTPEAVKANWTKICDFDNATKPKSIQESIGSIVEALN 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KI+S G VSAN TSRATS TS FA AIG K PP +Y EL+ IMYALGVGASIK+PKD
Sbjct: 301 KINSGGEVSANPTSRATSATTSEFARAIGHKFPPLYSSYAELDTIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI+ QKS+M GGLAEIPGLSIN AK+LHGEQYLEL+KP+PRA
Sbjct: 361 MKFIYEGSSDFSCLPTFGVILAQKSIMNGGLAEIPGLSINLAKILHGEQYLELHKPIPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKL+CEA+VAD+LDKGSG+VI++DVY+YS +ELIC+NQFS+F+VGSGG GGKRTSDK K
Sbjct: 421 GKLRCEAIVADILDKGSGLVILVDVYTYSGEELICYNQFSIFVVGSGGSGGKRTSDKAKA 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETG IVISN
Sbjct: 541 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGGIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKTPSEG LQST VFEEIGRRL+ IG EVVKKV AVFEWHITKG N
Sbjct: 601 AYVDLVPASAISAKTPSEGAGLQSTLVFEEIGRRLQGIGEEVVKKVRAVFEWHITKGENT 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPAKG+AD TI LSDEDFMEVVLGKLDPQKA FSGRLKARGNI
Sbjct: 661 AAKWTIDLKTGSGKVYQGPAKGSADVTITLSDEDFMEVVLGKLDPQKAVFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
+LSQKLQMILKDYAKL
Sbjct: 721 LLSQKLQMILKDYAKL 736
>emb|CAA64427.1| multifunctional protein 2 [Rattus norvegicus]
Length = 734
Score = 1287 bits (3330), Expect = 0.0, Method: Composition-based stats.
Identities = 635/734 (86%), Positives = 683/734 (93%), Gaps = 1/734 (0%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
SPLRFDGRV LVTGAG GLGRAY LAFAERGALVVVNDLGGDFKGVGKGS AADKVVEEI
Sbjct: 2 SPLRFDGRVGLVTGAGGGLGRAYGLAFAERGALVVVNDLGGDFKGVGKGSSAADKVVEEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
RRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRD SF+RISDEDWDII RV
Sbjct: 62 RRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDPSFSRISDEDWDIIQRV 121
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
HLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L IEG
Sbjct: 122 HLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVIEG 181
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 242
RK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG
Sbjct: 182 RKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 241
Query: 243 WIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKI 302
WIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NAS+P+SIQESTG IIEVL KI
Sbjct: 242 WIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASEPKSIQESTGGIIEVLHKI 301
Query: 303 DSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLK 362
DSEG +S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKDLK
Sbjct: 302 DSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDLK 360
Query: 363 FIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGK 422
F+YEGS DFSCLPT GVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+G+
Sbjct: 361 FVYEGSPDFSCLPTIGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRSGE 420
Query: 423 LKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAV 482
LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K AV
Sbjct: 421 LKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAAV 480
Query: 483 AIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSAR 542
A+P+RPPDAVL DTTS+NQAALYRLSGD NPLHIDP+FA +AGF+KPILHGLCTFGFSAR
Sbjct: 481 AVPSRPPDAVLRDTTSVNQAALYRLSGDSNPLHIDPSFAGIAGFEKPILHGLCTFGFSAR 540
Query: 543 RVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY 602
VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY
Sbjct: 541 HVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY 600
Query: 603 VDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGA 662
VDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+ A
Sbjct: 601 VDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVAA 660
Query: 663 KWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIML 722
KWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNIML
Sbjct: 661 KWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNIML 720
Query: 723 SQKLQMILKDYAKL 736
SQKLQMILKDYAKL
Sbjct: 721 SQKLQMILKDYAKL 734
>ref|NP_001007810.1| hydroxysteroid (17-beta) dehydrogenase 4 [Bos taurus]
emb|CAH17988.1| multifunctional protein 2 [Bos taurus]
Length = 736
Score = 1286 bits (3328), Expect = 0.0, Method: Composition-based stats.
Identities = 628/736 (85%), Positives = 678/736 (92%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRF+GRVVLVTGAG GLGRAYALAFAERGA VVVNDL GDF GVGKGSL+ADKVVE
Sbjct: 1 MASTLRFNGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLRGDFTGVGKGSLSADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVEEGEK+VKTALDAFGRID+V+NNAGILRDRSF+RISDEDWD I
Sbjct: 61 EIRRKGGKAVANYDSVEEGEKIVKTALDAFGRIDIVINNAGILRDRSFSRISDEDWDKIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSAS IYGNFGQANY AAKLGLLGL+N LA+
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASRIYGNFGQANYCAAKLGLLGLSNCLAV 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSRMTQ+++PEDLVEALKP+YVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRMTQSILPEDLVEALKPDYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LGA+VRQ+ PMTPEAVKANW KICDF+NA+KP+SIQES GSI+E L+
Sbjct: 241 AGWIGKLRWERSLGALVRQRTQPMTPEAVKANWTKICDFDNATKPKSIQESIGSIVEALN 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KI+S G VSAN TSRATS TS FA AIG K PP +Y EL+ IMYALGVGASIK+PKD
Sbjct: 301 KINSGGEVSANPTSRATSATTSEFARAIGHKFPPLYSSYAELDTIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI+ QKS+M GGLAEIPGLSIN AK+LHGEQYLEL+KP+PRA
Sbjct: 361 MKFIYEGSSDFSCLPTFGVILAQKSIMNGGLAEIPGLSINLAKILHGEQYLELHKPIPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKL+CEA+VAD+LDKGSG+VI++DVY+YS +ELIC+NQFS+F+VGSGG GGKRTSDK K
Sbjct: 421 GKLRCEAIVADILDKGSGLVILVDVYTYSGEELICYNQFSIFVVGSGGSGGKRTSDKAKA 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETG IVISN
Sbjct: 541 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGGIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKTPSEG LQST VFEEIGRRL+ IG EVVKKV AVFEWHITKG N
Sbjct: 601 AYVDLVPASAISAKTPSEGAGLQSTLVFEEIGRRLQGIGEEVVKKVRAVFEWHITKGENT 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPAKG+AD TI LSDEDFMEVVLGKLDPQKA FSGRLKARGNI
Sbjct: 661 AAKWTIDLKTGSGKVYQGPAKGSADVTITLSDEDFMEVVLGKLDPQKAVFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
+LSQKLQMILKDYAKL
Sbjct: 721 LLSQKLQMILKDYAKL 736
>gb|EDL09934.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Mus
musculus]
Length = 733
Score = 1279 bits (3309), Expect = 0.0, Method: Composition-based stats.
Identities = 627/736 (85%), Positives = 679/736 (92%), Gaps = 3/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRI ILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIGD--QYFRILRDRSFSRISDEDWDIIH 118
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 119 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 178
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 179 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 238
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 239 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 298
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG +S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 299 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 357
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 358 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 417
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 418 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 477
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 478 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 537
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 538 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 597
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 598 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 657
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 658 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 717
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 718 MLSQKLQMILKDYAKL 733
>emb|CAA73945.1| mutifunctional protein2 [Cavia porcellus]
Length = 735
Score = 1270 bits (3286), Expect = 0.0, Method: Composition-based stats.
Identities = 620/736 (84%), Positives = 688/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAG GLGRAYALAFAERGA V+V+DLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVIVDDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GG+AVANYDSVE GEK+VK ALDAFGRIDVVVNNAGIL RSF+RISDEDWDI+H
Sbjct: 61 EIRRKGGRAVANYDSVEAGEKIVKAALDAFGRIDVVVNNAGILTHRSFSRISDEDWDIVH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHL GSFQVTRAAW HMKKQ YGRIIMT+S++GIYGNFGQANYSAAKLGLLGL+N++AI
Sbjct: 121 RVHLWGSFQVTRAAWNHMKKQNYGRIIMTTSSAGIYGNFGQANYSAAKLGLLGLSNTIAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSR+TQTVMP+DLV+ALKPEYVAPLVLWLCH+SCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRLTQTVMPDDLVQALKPEYVAPLVLWLCHDSCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR+KN P+TPE VKANWKKICDF+NASKPQSIQESTG ++E+L
Sbjct: 241 AGWIGKLRWERTLGAIVRRKNEPVTPETVKANWKKICDFDNASKPQSIQESTGGMVEILH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE VS N TS ATSTA+ G+A AIG KLP FS +YTEL+ IMYALGVGAS+KDPK+
Sbjct: 301 KIDSEE-VSTNPTSHATSTASPGYASAIGYKLPSFSPSYTELDCIMYALGVGASVKDPKN 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEGS DFSCLPTFGVI+ QKS+ GGGLA++ GLSINFAKVLHGEQYL++YKP PRA
Sbjct: 360 LRFLYEGSPDFSCLPTFGVIVAQKSVFGGGLADVSGLSINFAKVLHGEQYLQIYKPFPRA 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCEAV+AD+LDKGSG+VI++DVY+YS +ELIC+NQFS+F+VGSGGFGGKRTS+K+KV
Sbjct: 420 GKLKCEAVIADILDKGSGLVIVLDVYAYSGEELICYNQFSVFVVGSGGFGGKRTSEKLKV 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIP+RPPDAV+TD TSL+QAALYRLSGDWNPLHIDPNFAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAIPSRPPDAVITDNTSLDQAALYRLSGDWNPLHIDPNFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVS+FKAIK RFAKPVYPGQTL+TEMWKEGNRIHFQTK+ ETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSKFKAIKVRFAKPVYPGQTLKTEMWKEGNRIHFQTKILETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKT EGG+LQST VFEEI RRLKDIG + VKKVNAVFEWHITKGGN
Sbjct: 600 AYVDLVPPSDLSAKTHPEGGELQSTRVFEEINRRLKDIGHKEVKKVNAVFEWHITKGGNT 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPA+G+ADT+I++SDEDFMEVVLGKLDPQKAFFSGRLKA+GNI
Sbjct: 660 AAKWTIDLKNGSGKVYQGPAEGSADTSILISDEDFMEVVLGKLDPQKAFFSGRLKAKGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYA L
Sbjct: 720 MLSQKLQMILKDYANL 735
>ref|NP_999471.1| hydroxysteroid (17-beta) dehydrogenase 4 [Sus scrofa]
emb|CAA55037.1| 17beta-estradiol dehydrogenase [Sus scrofa]
Length = 737
Score = 1268 bits (3281), Expect = 0.0, Method: Composition-based stats.
Identities = 623/737 (84%), Positives = 673/737 (91%), Gaps = 1/737 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S L F GRVVLVTGAG GLGR YALAFAERGA VVVNDLGGD KGVGKGSLAADKVVE
Sbjct: 1 MASMLNFYGRVVLVTGAGGGLGRTYALAFAERGASVVVNDLGGDMKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VK ALDAFGRIDVVVNNAGILRDRSF+RISDEDWD+I
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKIVKAALDAFGRIDVVVNNAGILRDRSFSRISDEDWDMIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQ +GRIIMTSSA+GIYGNFGQANYSAAKLGLLGL+NSLA+
Sbjct: 121 RVHLRGSFMVTRAAWDHMKKQNFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLSNSLAV 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNT+AP AGSRMTQ +PEDL+EALKPEYVAPLVLWLCHESCEENG +FEVG
Sbjct: 181 EGKKNNIHCNTVAPVAGSRMTQGFLPEDLIEALKPEYVAPLVLWLCHESCEENGSVFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGA+VRQKN PMTPEAVKANW KICDF+NA+KPQ IQ+S ++IE LS
Sbjct: 241 AGWIGKLRWERTLGALVRQKNQPMTPEAVKANWTKICDFDNATKPQRIQDSVSTVIEALS 300
Query: 301 KIDS-EGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
KIDS +GG+SAN+ S ATS A SG A+G K PPFS +YTE++ IMYA GVGASIK+PK
Sbjct: 301 KIDSSDGGISANNLSHATSAAPSGLVEAVGYKFPPFSSSYTEVDTIMYAFGVGASIKEPK 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
DLKFIYEG+SDFSCLPTFGVI+ QKS+ GGGLAEIPGLS+NF KVLHGE YLELYKPLP
Sbjct: 361 DLKFIYEGNSDFSCLPTFGVILAQKSLGGGGLAEIPGLSVNFTKVLHGEHYLELYKPLPN 420
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
AG LKCEAVVADVLDK SG+VI++DVYSYS KELIC+NQFS+F++GSGGFGGKRTSDK K
Sbjct: 421 AGDLKCEAVVADVLDKRSGLVILIDVYSYSGKELICYNQFSVFVMGSGGFGGKRTSDKDK 480
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
VAVAIPNRPPDA+LTDTTSLNQAALYRLSGDWNPLHIDP+FASLAGFD+PILHGLCTFGF
Sbjct: 481 VAVAIPNRPPDAILTDTTSLNQAALYRLSGDWNPLHIDPDFASLAGFDRPILHGLCTFGF 540
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VLQQ+AD DV RFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGD VIS
Sbjct: 541 SARHVLQQYADRDVLRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDTVIS 600
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
NAYVDL PTS T AK PSEGG LQS VFEEIGRRL+DIG E+VKKVNAVFEWHITKG
Sbjct: 601 NAYVDLVPTSDTLAKIPSEGGDLQSNLVFEEIGRRLQDIGQEMVKKVNAVFEWHITKGEK 660
Query: 660 IGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGN 719
I AKWTIDLK+G+GKVYQGPAKG+AD T ILSDE FMEVVLGKLDPQKAFFSGRLKARGN
Sbjct: 661 IAAKWTIDLKNGAGKVYQGPAKGSADATFILSDEVFMEVVLGKLDPQKAFFSGRLKARGN 720
Query: 720 IMLSQKLQMILKDYAKL 736
IMLSQKLQMILKDYAK+
Sbjct: 721 IMLSQKLQMILKDYAKI 737
>gb|EDM14436.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Rattus
norvegicus]
Length = 708
Score = 1250 bits (3234), Expect = 0.0, Method: Composition-based stats.
Identities = 614/706 (86%), Positives = 661/706 (93%), Gaps = 1/706 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG +S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQ 706
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQ 705
>gb|EAW48910.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_a [Homo
sapiens]
Length = 596
Score = 1212 bits (3136), Expect = 0.0, Method: Composition-based stats.
Identities = 596/599 (99%), Positives = 596/599 (99%), Gaps = 3/599 (0%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQK IIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG
Sbjct: 1 MKKQK---IIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 57
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV
Sbjct: 58 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 117
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 317
RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT
Sbjct: 118 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 177
Query: 318 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF
Sbjct: 178 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 237
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS
Sbjct: 238 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 297
Query: 438 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 497
GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT
Sbjct: 298 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 357
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK
Sbjct: 358 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 417
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS
Sbjct: 418 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 477
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ
Sbjct: 478 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 537
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 538 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 596
>ref|XP_001088200.1| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 isoform 3
[Macaca mulatta]
Length = 597
Score = 1179 bits (3049), Expect = 0.0, Method: Composition-based stats.
Identities = 581/599 (96%), Positives = 588/599 (98%), Gaps = 2/599 (0%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG
Sbjct: 1 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 60
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV
Sbjct: 61 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 120
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 317
RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEG VSANHTS AT
Sbjct: 121 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEG-VSANHTSHAT 179
Query: 318 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKF+YEGSSDFSCLPTF
Sbjct: 180 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFVYEGSSDFSCLPTF 239
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVIIGQKS+MGGGLAEIPGLSINFAKV+ GE ++ KPL R GKLKCEAVVADVLDKGS
Sbjct: 240 GVIIGQKSLMGGGLAEIPGLSINFAKVI-GEPSMKAEKPLKRVGKLKCEAVVADVLDKGS 298
Query: 438 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 497
GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT
Sbjct: 299 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 358
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARR+LQQFADNDVSRFK
Sbjct: 359 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRILQQFADNDVSRFK 418
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTS TSAKTPS
Sbjct: 419 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSDTSAKTPS 478
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGGKLQST VFEEIGRRLKD+GPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ
Sbjct: 479 EGGKLQSTLVFEEIGRRLKDVGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 538
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 539 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 597
>ref|XP_001378211.1| PREDICTED: similar to 17beta-hydroxysteroid dehydrogenase
[Monodelphis domestica]
Length = 719
Score = 1164 bits (3012), Expect = 0.0, Method: Composition-based stats.
Identities = 561/700 (80%), Positives = 641/700 (91%), Gaps = 1/700 (0%)
Query: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVV 97
VNDLGGDFKGVG+ S AAD VVEEI++RGGKAVANYDSVE GEKVVKTALDAFG+ID+V+
Sbjct: 20 VNDLGGDFKGVGRSSSAADNVVEEIKKRGGKAVANYDSVEAGEKVVKTALDAFGKIDIVI 79
Query: 98 NNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYG 157
NNAGILRDRSF RISDEDWDIIH+VHLRGSFQVTRAAW+HMKKQK+GRIIMTSSASGIYG
Sbjct: 80 NNAGILRDRSFVRISDEDWDIIHKVHLRGSFQVTRAAWDHMKKQKFGRIIMTSSASGIYG 139
Query: 158 NFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEY 217
NFGQANYSAAKLGL GL+N+LAIEGRK NIHCNTIAP AGSRMT++VMP+DLV+ALKP+Y
Sbjct: 140 NFGQANYSAAKLGLAGLSNTLAIEGRKFNIHCNTIAPTAGSRMTESVMPQDLVDALKPDY 199
Query: 218 VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKIC 277
VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKN PMTPEAVKANW+KIC
Sbjct: 200 VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNQPMTPEAVKANWRKIC 259
Query: 278 DFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSY 337
DFENA+ PQ+IQEST S+IEVL+KIDS+GGVS NHTS+A S T+ F AIG KLPP ++
Sbjct: 260 DFENANHPQTIQESTASVIEVLNKIDSQGGVSMNHTSQAASATTAAFTTAIGYKLPPRTF 319
Query: 338 AYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGL 397
+YTELEAIMYALGVGAS+K+P++LKF+YEG+SDFSCLPTFGVI QK MM GGL+E+PGL
Sbjct: 320 SYTELEAIMYALGVGASVKNPENLKFVYEGNSDFSCLPTFGVIPAQKCMMDGGLSEVPGL 379
Query: 398 SINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHN 457
+I++ KVLHGEQYLELYKPLP+ G+L EA++ D+LDKGSG+VI++DVYSYS KELIC N
Sbjct: 380 TIDYTKVLHGEQYLELYKPLPKTGQLTNEAIIVDILDKGSGLVILLDVYSYSGKELICFN 439
Query: 458 QFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHID 517
QF++F+VGSGGFGGK+TSDK KV V P RPPDA+LTDTTSLNQA LYRLSGDWNPLHID
Sbjct: 440 QFTVFVVGSGGFGGKKTSDKAKVTVPPPKRPPDAILTDTTSLNQAVLYRLSGDWNPLHID 499
Query: 518 PNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEM 577
P+FASL GF+KPILHGLC+FG++AR +LQQF +NDVSRF+AIKARFAKPVYPGQTL TEM
Sbjct: 500 PSFASLGGFEKPILHGLCSFGYAARHILQQFGNNDVSRFRAIKARFAKPVYPGQTLLTEM 559
Query: 578 WKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGT-SAKTPSEGGKLQSTFVFEEIGRRLK 636
WKEGNRIHFQTKVQETGDIV+SNAYVDL PTS S K S+ G LQST VFEEIGRR+K
Sbjct: 560 WKEGNRIHFQTKVQETGDIVLSNAYVDLVPTSDVLSTKVSSKDGTLQSTLVFEEIGRRIK 619
Query: 637 DIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFM 696
D+G E+VKKVNAVF+W+ITK G A+WTIDLK+GSG++YQGPA+G+ADT+ LSDE+FM
Sbjct: 620 DVGKELVKKVNAVFQWNITKHGQTAAQWTIDLKNGSGELYQGPARGSADTSFTLSDENFM 679
Query: 697 EVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
EVVLGKL+PQKAFFSG+L+ +GNIMLSQKL+MILKD+AKL
Sbjct: 680 EVVLGKLNPQKAFFSGKLQVKGNIMLSQKLEMILKDHAKL 719
>ref|XP_859266.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 3 [Canis familiaris]
Length = 599
Score = 1090 bits (2820), Expect = 0.0, Method: Composition-based stats.
Identities = 520/599 (86%), Positives = 555/599 (92%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LAIEG+ SNIHCNTIAP AG
Sbjct: 1 MKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLAIEGKTSNIHCNTIAPTAG 60
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEVG GWIGKLRWERTLGAIV
Sbjct: 61 SRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEVGGGWIGKLRWERTLGAIV 120
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 317
RQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V++ IDS+GGVS NHTS A
Sbjct: 121 RQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVVNTIDSDGGVSTNHTSHAA 180
Query: 318 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
STATS FAGAIG K PPFS AYTELE IMYALGVGAS+K+PKD+KFIYEGS+DFSCLPTF
Sbjct: 181 STATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPKDMKFIYEGSTDFSCLPTF 240
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPRAG L+CEAVVADVLDKGS
Sbjct: 241 GVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPRAGNLRCEAVVADVLDKGS 300
Query: 438 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 497
G VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDKVK VA+PNRPPDAVLTDTT
Sbjct: 301 GSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVKATVAVPNRPPDAVLTDTT 360
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGFSAR VLQ+FADNDVSRFK
Sbjct: 361 SLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGFSARHVLQKFADNDVSRFK 420
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVISNAYVDL PTS TSA+TPS
Sbjct: 421 AIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVISNAYVDLMPTSDTSAQTPS 480
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGNI AKWTIDLKSG GKVYQ
Sbjct: 481 EGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGNIAAKWTIDLKSGFGKVYQ 540
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 541 GPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 599
>ref|NP_990274.1| hydroxysteroid (17-beta) dehydrogenase 4 [Gallus gallus]
gb|AAC60249.1| 17-beta-hydroxysteroid dehydrogenase type IV [Gallus gallus]
Length = 735
Score = 1085 bits (2806), Expect = 0.0, Method: Composition-based stats.
Identities = 528/738 (71%), Positives = 621/738 (84%), Gaps = 5/738 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M + LRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG GK S AADKVV
Sbjct: 1 MAAGLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGYGKSSSAADKVVS 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAV NYDSVE+GEK+VK+AL+AFGRID+V+NNAGILRDRSF RISDEDWDIIH
Sbjct: 61 EIRANGGKAVPNYDSVEDGEKLVKSALEAFGRIDIVINNAGILRDRSFVRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
R+HLRGSF VTRAAW HMK QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGL+N++AI
Sbjct: 121 RIHLRGSFLVTRAAWNHMKNQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLSNTIAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK NIHCNTIAP AGSR+TQTVMP+DL++A KPEYVAPLVLWLCHE+C ENG LFEVG
Sbjct: 181 EGRKYNIHCNTIAPTAGSRLTQTVMPQDLIDAFKPEYVAPLVLWLCHETCMENGSLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LGAIVR K+ PMTPEAV+ W+K+CDF NASKP+SIQES + + LS
Sbjct: 241 AGWIGKLRWERSLGAIVRGKDQPMTPEAVRDKWEKVCDFNNASKPRSIQESISVLNDALS 300
Query: 301 KIDSEGGVSANHT-SRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+I+S+G +S N T SR+ ++ +G++L Y YT LE I+YALGVG S KDP
Sbjct: 301 QIESQGSISMNSTNSRSVVSSAVDTTSLVGRELTTKVYKYTHLEPILYALGVGMSTKDPD 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
LKF++EGS +F CLPTFGVI Q SM G+ IPGL ++ AK+LHGEQYLELYKPLP
Sbjct: 361 HLKFLFEGSEEFCCLPTFGVIPAQTSMF-DGVPSIPGLDMDLAKMLHGEQYLELYKPLPT 419
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
+G+L+ + +AD+LDKGSG V+++DV +Y K+L+C+NQFSLF VG+GGFGGKRTS+K K
Sbjct: 420 SGELRSVSTIADLLDKGSGAVLLIDVNTYCGKDLVCYNQFSLFFVGAGGFGGKRTSEKAK 479
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
V V P RPPDA+L+D T+ +QAALYRLSGDWNPLH+DP+FA+L GF KPILHGLCTFGF
Sbjct: 480 VTVNPPKRPPDAILSDVTTSDQAALYRLSGDWNPLHLDPSFAALGGFQKPILHGLCTFGF 539
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
+AR VL+QFA+NDV+RFKAIK RFAKPV+PGQTLQTEMWKEGNRIHFQTKV+ETGD+ I+
Sbjct: 540 AARNVLKQFANNDVTRFKAIKVRFAKPVFPGQTLQTEMWKEGNRIHFQTKVKETGDLAIA 599
Query: 600 NAYVDL-APTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGG 658
YVD+ + SA P+ G LQS VFEEIGRR+K++G E+V+KVNAVF+W ITK G
Sbjct: 600 GGYVDIVSALDKPSALEPTAG--LQSDLVFEEIGRRIKEVGHELVRKVNAVFQWDITKDG 657
Query: 659 NIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARG 718
+WTIDLK+GSG VYQGPA+ +ADTT LSD+DFM+VV K +PQKAFFSG+LK +G
Sbjct: 658 KTAVQWTIDLKNGSGSVYQGPARSSADTTFTLSDQDFMDVVQKKTNPQKAFFSGKLKVKG 717
Query: 719 NIMLSQKLQMILKDYAKL 736
NIMLSQKL+MILKDYAKL
Sbjct: 718 NIMLSQKLEMILKDYAKL 735
>ref|NP_001027490.1| hypothetical protein LOC613082 [Xenopus tropicalis]
gb|AAH96498.1| Hypothetical protein mgc108050 [Xenopus tropicalis]
Length = 740
Score = 1085 bits (2806), Expect = 0.0, Method: Composition-based stats.
Identities = 524/735 (71%), Positives = 622/735 (84%), Gaps = 3/735 (0%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
LRFDGRVVLVTGAG GLGR YALAFAERGA V+VNDLGGD KG GK S AADKVVEEIR
Sbjct: 6 LRFDGRVVLVTGAGGGLGRTYALAFAERGASVIVNDLGGDIKGEGKSSSAADKVVEEIRA 65
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
+GGKAVANYDSVE GEK+V+TALDAFGRID+VVNNAGILRDRSFARISD DWDIIHRVHL
Sbjct: 66 KGGKAVANYDSVEAGEKLVQTALDAFGRIDIVVNNAGILRDRSFARISDADWDIIHRVHL 125
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
+G+F +TRAAW HMK QK+GRIIMTSSA+GIYGNFGQANYSAAKLGL+GL+N+LAIEG K
Sbjct: 126 KGAFLITRAAWNHMKNQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLVGLSNTLAIEGTK 185
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
NIH N IAP AGSR+TQTVMP+DL++ALKPEYV PLVLWLCHESC+E G LFEVGAGW+
Sbjct: 186 YNIHSNCIAPTAGSRLTQTVMPQDLLDALKPEYVTPLVLWLCHESCQETGSLFEVGAGWV 245
Query: 245 GKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDS 304
GKLRWER+LGAI+RQKN PMTPEAV+ W KI DF+NA KPQ+IQ+S + +VLS+ DS
Sbjct: 246 GKLRWERSLGAIIRQKNRPMTPEAVRDEWAKISDFDNADKPQTIQDSINPLYQVLSQTDS 305
Query: 305 EGGVSANHTSRATSTATSGF--AGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLK 362
E G+S N TS+ TS +TS AIGQKLP +Y Y+ LE I+YALGVG S +DP LK
Sbjct: 306 EKGMSMNPTSQGTSLSTSSIDPVKAIGQKLPLTTYTYSHLEPILYALGVGMSTRDPDHLK 365
Query: 363 FIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGK 422
F+YEGS DFSCLP+FGVI+ Q + M GGLA +PGL+I+F +VLHGEQYLE+YKPLP +G+
Sbjct: 366 FLYEGSEDFSCLPSFGVIVSQAAFMSGGLASVPGLNIDFTRVLHGEQYLEIYKPLPTSGE 425
Query: 423 LKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAV 482
+ A VAD++DKGSG +I++DV++Y +L+C+NQFS+F+VG+GGFGGKR+S K K
Sbjct: 426 MTSHATVADIMDKGSGAIILLDVHTYHGVDLVCYNQFSVFVVGAGGFGGKRSSSKAKATA 485
Query: 483 AIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSAR 542
P+RPPD V+TD T+ +QAALYRLSGDWNPLHIDP+FA++ GF+KPILHGLC+FGFSAR
Sbjct: 486 NPPSRPPDVVVTDATNADQAALYRLSGDWNPLHIDPSFAAMGGFEKPILHGLCSFGFSAR 545
Query: 543 RVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY 602
VL+ FA+NDV++FKAIK RFAKPV PGQTLQTEMWKEGNRI QTKV++TG+I I+ AY
Sbjct: 546 HVLKHFANNDVTKFKAIKVRFAKPVLPGQTLQTEMWKEGNRIFLQTKVKDTGEIAIAGAY 605
Query: 603 VDLAPTSGT-SAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIG 661
VDL T +K P + G LQS VF+EI RR+KD+G ++VKKVNAVF+W ITK G
Sbjct: 606 VDLTSTENNLESKGPVQDGGLQSDLVFDEISRRVKDLGEQLVKKVNAVFQWDITKDGKPA 665
Query: 662 AKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIM 721
++WTIDLKSGSG+VY+G A+G ADT+ LSDEDFME+VLG L+PQKAFF+G+LK +GNIM
Sbjct: 666 SQWTIDLKSGSGEVYRGKARGRADTSFTLSDEDFMELVLGNLNPQKAFFAGKLKVKGNIM 725
Query: 722 LSQKLQMILKDYAKL 736
LSQKL+MILKDYAKL
Sbjct: 726 LSQKLEMILKDYAKL 740
>ref|NP_001086063.1| MGC81885 protein [Xenopus laevis]
gb|AAH74145.1| MGC81885 protein [Xenopus laevis]
Length = 741
Score = 1072 bits (2773), Expect = 0.0, Method: Composition-based stats.
Identities = 523/736 (71%), Positives = 620/736 (84%), Gaps = 4/736 (0%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
LRFDGRVVLVTGAG GLGR YALAFAERGA VVVNDLGGD KG GK S AADKVVEEIR
Sbjct: 6 LRFDGRVVLVTGAGGGLGRTYALAFAERGASVVVNDLGGDIKGEGKSSFAADKVVEEIRA 65
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
+GGKAVANYDSVE GEK+V++ALDAFGRID+++NNAGILRDRSFARISD DWDIIHRVHL
Sbjct: 66 KGGKAVANYDSVEAGEKLVQSALDAFGRIDIIINNAGILRDRSFARISDADWDIIHRVHL 125
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
+GSF +TRAAW HMK QK+GRIIMTSSA+GIYGNFGQANYSAAKLGL+GL+N+LAIEG K
Sbjct: 126 KGSFLITRAAWNHMKNQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLVGLSNTLAIEGTK 185
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
NI N IAP AGSR+TQTVMP+DL++ALKPEYV PLVLWLCHE C+E G LFEVGAGW+
Sbjct: 186 YNIQSNCIAPTAGSRLTQTVMPQDLLDALKPEYVTPLVLWLCHERCQETGSLFEVGAGWV 245
Query: 245 GKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDS 304
GKLRWER+LGAI+RQ N PMTPEAV+ W KICDF+NA KPQ+IQ+S + +VLS++DS
Sbjct: 246 GKLRWERSLGAIIRQTNRPMTPEAVRDEWAKICDFDNADKPQTIQDSINPLYQVLSQVDS 305
Query: 305 EGGVSANHTSRATSTATSGF--AGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLK 362
E GVS N TS TS ++S A AIGQKLP Y Y+ LE I+YALGVG S +DP LK
Sbjct: 306 EKGVSMNPTSHGTSLSSSSIDPAKAIGQKLPVTLYKYSHLEPILYALGVGMSTRDPDHLK 365
Query: 363 FIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGK 422
F+YEGS DFSCLP+FGV++ Q + M GGLA +PGL+I+F +VLHGEQYLE+YKPLP +G+
Sbjct: 366 FLYEGSEDFSCLPSFGVVVSQAAFMSGGLASVPGLNIDFTRVLHGEQYLEVYKPLPTSGE 425
Query: 423 LKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAV 482
+ A VAD++DKGSG +I++DV++Y +LIC+NQFS+F+VG+GGFGGKR+S K K
Sbjct: 426 MTSHATVADIMDKGSGAIILLDVHTYHGADLICYNQFSVFVVGAGGFGGKRSSSKAKATE 485
Query: 483 AIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSAR 542
P+RPPD V D T+ +QAALYRLSGDWNPLHIDP+FA+L GF++PILHGLC+FGFSAR
Sbjct: 486 NPPSRPPDVVEIDVTNADQAALYRLSGDWNPLHIDPSFAALGGFERPILHGLCSFGFSAR 545
Query: 543 RVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY 602
VL+ FA+NDV++FKAIK RFAKPV PGQTLQTEMWKEGNRI QTKV+ETG+I I+ AY
Sbjct: 546 HVLKHFANNDVTKFKAIKVRFAKPVLPGQTLQTEMWKEGNRIFLQTKVKETGEIAIAGAY 605
Query: 603 VDLAPT-SGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIG 661
VDLA T + +K + G LQS VFEEI RR+KD+G ++VKKVNAVF+W ITK G
Sbjct: 606 VDLASTVNNPESKAAVQDGGLQSDLVFEEISRRVKDVGGQLVKKVNAVFQWDITKDGKTA 665
Query: 662 AKWTIDLKS-GSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
++WTIDLKS GSG+VY+G A+G ADT+ LSDEDFME+VLGK++PQKAFF+G+LK +GNI
Sbjct: 666 SQWTIDLKSGGSGEVYRGKARGRADTSFTLSDEDFMELVLGKVNPQKAFFAGKLKVKGNI 725
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKL+MILKDYAKL
Sbjct: 726 MLSQKLEMILKDYAKL 741
>ref|XP_001512505.1| PREDICTED: similar to 17beta-hydroxysteroid dehydrogenase
[Ornithorhynchus anatinus]
Length = 752
Score = 1069 bits (2765), Expect = 0.0, Method: Composition-based stats.
Identities = 505/713 (70%), Positives = 600/713 (84%), Gaps = 16/713 (2%)
Query: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVV 97
+NDLGGDFKG GK S AA KVVEEIR++GGKAVANYDSVE GEK+VK ALDAFGRID+V+
Sbjct: 42 MNDLGGDFKGEGKSSSAAAKVVEEIRKKGGKAVANYDSVEAGEKIVKAALDAFGRIDIVI 101
Query: 98 NNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYG 157
NNAGILRDRSF RISD DWDIIHRVHLRGSFQVTRAAW+HMK+Q +GRIIMTSSA+GIYG
Sbjct: 102 NNAGILRDRSFVRISDHDWDIIHRVHLRGSFQVTRAAWDHMKQQNFGRIIMTSSAAGIYG 161
Query: 158 NFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEY 217
NFGQANYSAAKLGL+GL+N+LAIEGRK NIHCN+IAP AGSR+TQTVM +D+V+ALKPEY
Sbjct: 162 NFGQANYSAAKLGLVGLSNTLAIEGRKYNIHCNSIAPTAGSRLTQTVMTQDMVDALKPEY 221
Query: 218 VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKIC 277
VAPLVLWLCHESC ENGGLFEVGAGWIGKLRWERTLGAIVRQKN PMTPEAVKA+WKKIC
Sbjct: 222 VAPLVLWLCHESCMENGGLFEVGAGWIGKLRWERTLGAIVRQKNQPMTPEAVKADWKKIC 281
Query: 278 DFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSY 337
DF+N +KP++I+ESTG ++EVLSKI+ G VS N TS+A S A S + K+ P+++
Sbjct: 282 DFDNVTKPRTIEESTGGMLEVLSKIEDGGAVSMNPTSQAASVAKSQLDRVVEYKISPWTF 341
Query: 338 AYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGL 397
Y++LE I+YAL VGAS+K+P D+KF+YE +++FSCLPTFGVI QK + G ++IPG+
Sbjct: 342 EYSQLETIIYALAVGASVKNPDDMKFVYERNANFSCLPTFGVIPAQKCLSTGLFSDIPGI 401
Query: 398 SINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHN 457
IN K+LHGEQYLE+YK P +GKL E V+ADVLDKGSG VI+ DV +Y EKELIC+N
Sbjct: 402 QINMEKLLHGEQYLEVYKLFPSSGKLWSEGVIADVLDKGSGSVILFDVTTYHEKELICYN 461
Query: 458 QFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHID 517
QFSLF++GSGGFGGKRTS+KVK ++ +P+RPPDAV D TSLNQAALYRLSGDWNPLHID
Sbjct: 462 QFSLFVIGSGGFGGKRTSEKVKPSLPVPDRPPDAVCYDVTSLNQAALYRLSGDWNPLHID 521
Query: 518 PNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEM 577
P+FA+L GF+KPILHGLC+FGFSAR VL QFADND +RF+AIK RFAKPVYPGQTLQTEM
Sbjct: 522 PDFAALGGFEKPILHGLCSFGFSARHVLHQFADNDPARFRAIKVRFAKPVYPGQTLQTEM 581
Query: 578 WKEGNRIHFQTKVQETGDIVISNAYVDLAPTS-----------GTSAKTPS---EGGKLQ 623
WK GNRIHFQTKV ETG+IVISNAYVDL P+S G S + PS EG LQ
Sbjct: 582 WKNGNRIHFQTKVTETGNIVISNAYVDLVPSSDETSDNRTIKVGESTRIPSLCVEG--LQ 639
Query: 624 STFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGA 683
S +F+ IG+R+K+IG E+VKKV+AV + +ITKGG A WTIDLK+GSG+VYQGPAK
Sbjct: 640 SNIIFDVIGQRIKEIGKELVKKVSAVIQLNITKGGKTAAIWTIDLKNGSGEVYQGPAKVP 699
Query: 684 ADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
T LSDEDF+++V+G+L+P +AFF+GR+K GN++++ L MILK Y+KL
Sbjct: 700 PQATFTLSDEDFVKIVVGRLNPHQAFFNGRIKVEGNLIIAHNLNMILKTYSKL 752
>dbj|BAF74749.1| hydroxysteroid (17-beta) dehydrogenase 4 [Fundulus heteroclitus]
Length = 738
Score = 1061 bits (2744), Expect = 0.0, Method: Composition-based stats.
Identities = 517/736 (70%), Positives = 608/736 (82%), Gaps = 4/736 (0%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
L F+GRVVLVTGAG GLG+ YALAFA RGA VVVNDLG D KG G+ S AADKVVEEIR
Sbjct: 3 LSFEGRVVLVTGAGGGLGKEYALAFASRGASVVVNDLGVDTKGGGRSSAAADKVVEEIRA 62
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
+GGKAVANYDSVE+GEK++++ALDAFGRID+VVNNAGILRDRSFAR SD DWD+IHR+HL
Sbjct: 63 KGGKAVANYDSVEDGEKLIQSALDAFGRIDIVVNNAGILRDRSFARTSDLDWDLIHRIHL 122
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
RGSF VTRAAW HMK QK+GRIIMT+SA+GIYGNFGQANYSAAKLGLLGLAN+LAIEG K
Sbjct: 123 RGSFLVTRAAWNHMKNQKFGRIIMTASAAGIYGNFGQANYSAAKLGLLGLANTLAIEGHK 182
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
NIHCNTIAP AGSR+T+TVMP DLV +LKPEYVAPLVLWLCHE C+ENGGLFEVGAGWI
Sbjct: 183 YNIHCNTIAPVAGSRLTETVMPPDLVASLKPEYVAPLVLWLCHEQCKENGGLFEVGAGWI 242
Query: 245 GKLRWERTLGAIVRQKNHPMTPEAVKA-NWKKICDFENASKPQSIQESTGSIIEVLSKID 303
GKLRWERT G VRQ+N PMTPE V +W ICDFENA+KP ++QES S++ VLS+++
Sbjct: 243 GKLRWERTQGRTVRQRNKPMTPEGVPGTSWDAICDFENATKPANVQESLHSVVSVLSQVE 302
Query: 304 SEGGVSANHTSRATSTATSGF---AGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
S+G V AN T+ A S A+ A A+GQKLP S+++T + I+YALGVG S KDP +
Sbjct: 303 SDGDVGANPTAAAASGASGSGINPAEAVGQKLPTSSFSFTPTQCILYALGVGMSTKDPDN 362
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEG DFSCLPTFGVI Q + MGGGL+ +PGLSI+F +VLHGEQYLELYKPLP +
Sbjct: 363 LRFLYEGHQDFSCLPTFGVIPSQAATMGGGLSSVPGLSIDFTQVLHGEQYLELYKPLPTS 422
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G L E VADVLDKGSG VI++DV SYS EL+C+NQFS+F+VG+ FGGKR+SDK K
Sbjct: 423 GTLTSETTVADVLDKGSGAVILLDVNSYSGDELVCYNQFSVFVVGARRFGGKRSSDKAKA 482
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
+ P R PDAV+ ++T+ +QAALYRLSGDWNPLHIDP+FA++ GF PILHGLC+FGF+
Sbjct: 483 PLPPPKRAPDAVVIESTTRDQAALYRLSGDWNPLHIDPSFAAMGGFSAPILHGLCSFGFA 542
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQ+FA+ND S+FKAIK RFAKPV+PGQ+LQTEMWKEG+RIH Q KV+ETGD+ ++
Sbjct: 543 ARHVLQRFANNDPSKFKAIKVRFAKPVFPGQSLQTEMWKEGSRIHIQCKVKETGDVALAG 602
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
YVDL TS S +T +GG LQS VF EIGRR+ ++G E+VKKVNAVF W ITK G
Sbjct: 603 GYVDLHGTSEASPETLPQGGGLQSELVFAEIGRRVTELGSELVKKVNAVFGWEITKDGKK 662
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
A WTIDLK+GSG + +GP G AD T +SDEDFM+VV GKL PQKAFFSG+LK RGNI
Sbjct: 663 AADWTIDLKNGSGSLLKGPYGGKADVTFTVSDEDFMQVVTGKLPPQKAFFSGKLKVRGNI 722
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKL++ILKDYAKL
Sbjct: 723 MLSQKLEVILKDYAKL 738
>ref|NP_956430.1| hydroxysteroid (17-beta) dehydrogenase 4 [Danio rerio]
gb|AAN62014.1|AF439319_1 17-beta-hydroxysteroid dehydrogenase type 4 [Danio rerio]
gb|AAH44422.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Danio rerio]
gb|AAI65653.1| Hsd17b4 protein [synthetic construct]
Length = 725
Score = 1030 bits (2663), Expect = 0.0, Method: Composition-based stats.
Identities = 502/736 (68%), Positives = 599/736 (81%), Gaps = 11/736 (1%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M PLRFDG+VVLVTGAG GLGR YALAF +RGA V+VNDLGGD KG GK S AADKVVE
Sbjct: 1 MSVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAVIVNDLGGDIKGGGKSSAAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAVANYDSVE+GEK+++TALDAFGRIDVVVNNAGILRDRSFAR SD DWD+I
Sbjct: 61 EIRAAGGKAVANYDSVEDGEKLIQTALDAFGRIDVVVNNAGILRDRSFARTSDVDWDLIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMK+QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGLAN+LAI
Sbjct: 121 RVHLRGSFLVTRAAWNHMKQQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K NIHCNTIAP AGSR+T+TVMP DLV++LK EYVAPLVLWLCHESC+EN GLFEVG
Sbjct: 181 EGQKYNIHCNTIAPTAGSRLTETVMPPDLVQSLKAEYVAPLVLWLCHESCQENSGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LG IVRQK+ +TPEAV+ W+ ICDF NA+KP SIQES +++EVLS
Sbjct: 241 AGWIGKLRWERSLGRIVRQKSECVTPEAVRDAWRDICDFTNATKPASIQESLQTLVEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
+++ E + AN T+ AT+ A AIG LP ++ +T + I+YALGVG S +DP+
Sbjct: 301 RVEDERKIGANPTAVATNPAQ-----AIGHVLPDMTFTHTHMNCILYALGVGVSSRDPQQ 355
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEG + FSCLPTFGVI Q +++ GL IPGL I+F ++LHGEQYLELYKPLP +
Sbjct: 356 LQFLYEGHTHFSCLPTFGVIPAQGALL--GLGSIPGLDIDFTRLLHGEQYLELYKPLPTS 413
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G L A VADVLDKGSG++I++DV++YSE+EL+C+NQFS+F+VGSGGFGGKR S K
Sbjct: 414 GTLTSRATVADVLDKGSGMLILLDVHTYSEQELLCYNQFSVFIVGSGGFGGKRVSQKAVA 473
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
A P+RP DAV+ + TS +QAALYRLSGDWNPLHIDPNFA++ GF PILHGLC+FGF+
Sbjct: 474 PAAPPDRPADAVVVEETSRDQAALYRLSGDWNPLHIDPNFAAMGGFQSPILHGLCSFGFA 533
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VL+QFA NDVSRFKA+K RF KPVYPGQ+LQTEMWKE +R+H Q V+E+G +V+S
Sbjct: 534 ARHVLKQFAGNDVSRFKAMKVRFVKPVYPGQSLQTEMWKENSRVHIQCTVKESGAVVLSG 593
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AY+DL P + + P +LQS VF EI RR+KD G E+VKKVNAVF W IT G
Sbjct: 594 AYIDLHPAASVNTGPPQT--ELQSDLVFAEIERRIKDSGEELVKKVNAVFGWEITTDGET 651
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
WT+DLK+G G V + AK AD T +SD+DFMEVV+GKL+PQKAFF+G+LK +GNI
Sbjct: 652 RRHWTVDLKTGRGSVQRAAAK--ADVTFTVSDQDFMEVVMGKLNPQKAFFAGKLKVKGNI 709
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKL+ +LKD A+L
Sbjct: 710 MLSQKLEAVLKDQARL 725
>gb|AAK27967.1|AF241285_1 17-beta-hydroxysteroid dehydrogenase type 4 [Danio rerio]
Length = 725
Score = 1030 bits (2662), Expect = 0.0, Method: Composition-based stats.
Identities = 502/736 (68%), Positives = 599/736 (81%), Gaps = 11/736 (1%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M PLRFDG+VVLVTGAG GLGR YALAF +RGA V+VNDLGGD KG GK S AADKVVE
Sbjct: 1 MSVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAVIVNDLGGDIKGGGKSSAAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAVANYDSVE+GEK+++TALDAFGRIDVVVNNAGILRDRSFAR SD DWD+I
Sbjct: 61 EIRAAGGKAVANYDSVEDGEKLIQTALDAFGRIDVVVNNAGILRDRSFARTSDVDWDLIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMK+QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGLAN+LAI
Sbjct: 121 RVHLRGSFLVTRAAWNHMKQQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K NIHCNTIAP AGSR+T+TVMP DLV++LK EYVAPLVLWLCHESC+EN GLFEVG
Sbjct: 181 EGQKYNIHCNTIAPTAGSRLTETVMPPDLVQSLKAEYVAPLVLWLCHESCQENSGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LG IVRQK+ +TPEAV+ W+ ICDF NA+KP SIQES +++EVLS
Sbjct: 241 AGWIGKLRWERSLGRIVRQKSECVTPEAVRDAWRDICDFTNATKPASIQESLQTLVEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
+++ E + AN T+ AT+ A AIG LP ++ +T + I+YALGVG S +DP+
Sbjct: 301 RVEDERKIGANPTAVATNPAQ-----AIGHVLPDMTFTHTHMNCILYALGVGVSSRDPQQ 355
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEG + FSCLPTFGVI Q +++ GL IPGL I+F ++LHGEQYLELYKPLP +
Sbjct: 356 LQFLYEGHTHFSCLPTFGVIPAQGALL--GLGSIPGLDIDFTRLLHGEQYLELYKPLPTS 413
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G L A VADVLDKGSG++I++DV++YSE+EL+C+NQFS+F+VGSGGFGGKR S K
Sbjct: 414 GTLTSRATVADVLDKGSGMLILLDVHTYSEQELLCYNQFSVFIVGSGGFGGKRVSQKAVA 473
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
A P+RP DAV+ + TS +QAALYRLSGDWNPLHIDPNFA++ GF PILHGLC+FGF+
Sbjct: 474 PAAPPDRPADAVVVEETSKDQAALYRLSGDWNPLHIDPNFAAMGGFQSPILHGLCSFGFA 533
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VL+QFA NDVSRFKA+K RF KPVYPGQ+LQTEMWKE +R+H Q V+E+G +V+S
Sbjct: 534 ARHVLKQFAGNDVSRFKAMKVRFVKPVYPGQSLQTEMWKENSRVHIQCTVKESGAVVLSG 593
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AY+DL P + + P +LQS VF EI RR+KD G E+VKKVNAVF W IT G
Sbjct: 594 AYIDLHPAASVNTGPPQT--ELQSDLVFAEIERRIKDSGEELVKKVNAVFGWEITTDGET 651
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
WT+DLK+G G V + AK AD T +SD+DFMEVV+GKL+PQKAFF+G+LK +GNI
Sbjct: 652 RRHWTVDLKTGRGSVQRAAAK--ADVTFTVSDQDFMEVVMGKLNPQKAFFAGKLKVKGNI 709
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKL+ +LKD A+L
Sbjct: 710 MLSQKLEAVLKDQARL 725
>gb|AAH65945.1| Hsd17b4 protein [Danio rerio]
Length = 725
Score = 1026 bits (2652), Expect = 0.0, Method: Composition-based stats.
Identities = 501/736 (68%), Positives = 597/736 (81%), Gaps = 11/736 (1%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M PLRFDG+VVLVTGAG GLGR YALAF +RGA V+VNDLGGD KG GK S AADKVVE
Sbjct: 1 MSVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAVIVNDLGGDIKGGGKSSAAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAVANYDSVE+GEK+++TALDAFGRIDVVVNNAGILRDRSFAR SD DWD+I
Sbjct: 61 EIRAAGGKAVANYDSVEDGEKLIQTALDAFGRIDVVVNNAGILRDRSFARTSDVDWDLIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMK+QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGLAN+LAI
Sbjct: 121 RVHLRGSFLVTRAAWNHMKQQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K NIHCNTIAP AGSR+T+TVMP DLV++LK EYVAPLVLWLCHESC+EN GLFEVG
Sbjct: 181 EGQKYNIHCNTIAPTAGSRLTETVMPPDLVQSLKAEYVAPLVLWLCHESCQENSGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LG IVRQK+ +TPEAV+ W+ ICDF NA+KP SIQES +++EVLS
Sbjct: 241 AGWIGKLRWERSLGRIVRQKSECVTPEAVRDAWRDICDFTNATKPASIQESLQTLVEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
+++ E + AN T+ AT+ A AIG LP ++ +T + I+YALGVG S +DP+
Sbjct: 301 RVEDERKIEANPTAVATNPAQ-----AIGHVLPDMTFTHTHMNCILYALGVGVSSRDPQQ 355
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEG + FSCLPTFGVI Q +++ GL IPGL I+F ++LHGEQYLELYK LP +
Sbjct: 356 LQFLYEGHTHFSCLPTFGVIPAQGALL--GLGSIPGLDIDFTRLLHGEQYLELYKSLPTS 413
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G L A VADVLDKGSG++I++DV++YSE+EL+C+NQFS+F+VGSGGFGGKR S K
Sbjct: 414 GTLTSRATVADVLDKGSGMLILLDVHTYSEQELLCYNQFSVFIVGSGGFGGKRVSQKAVA 473
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
A P+RP DAV+ + TS +QAALYRLSGDWNPLHIDPNFA++ GF PILHGLC+FGF+
Sbjct: 474 PAAPPDRPADAVVVEETSKDQAALYRLSGDWNPLHIDPNFAAMGGFQSPILHGLCSFGFA 533
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VL+QFA NDVSRFKA+K RF KPVYPGQ+LQTEMWKE +R+H Q V+E+G +V+S
Sbjct: 534 ARHVLKQFAGNDVSRFKAMKVRFVKPVYPGQSLQTEMWKENSRVHIQCTVKESGAVVLSG 593
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AY+DL P + + P +LQS VF EI RR+KD G E+VKKVNAVF W IT G
Sbjct: 594 AYIDLHPAASVNTGPPQT--ELQSDLVFAEIERRIKDSGEELVKKVNAVFGWEITTDGET 651
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
WT+DLK+G G V + AK AD T +SD DFMEVV+GKL+PQKAFF+G+LK +GNI
Sbjct: 652 RRHWTVDLKTGRGSVQRAAAK--ADVTFTVSDRDFMEVVMGKLNPQKAFFAGKLKVKGNI 709
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKL+ +LKD A+L
Sbjct: 710 MLSQKLEAVLKDQARL 725
>gb|EDM14435.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_a [Rattus
norvegicus]
gb|EDM14437.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_a [Rattus
norvegicus]
Length = 582
Score = 987 bits (2551), Expect = 0.0, Method: Composition-based stats.
Identities = 480/562 (85%), Positives = 524/562 (93%), Gaps = 1/562 (0%)
Query: 145 RIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTV 204
RIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L IEGRK+NIHCNTIAPNAGSRMT+TV
Sbjct: 19 RIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVIEGRKNNIHCNTIAPNAGSRMTETV 78
Query: 205 MPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPM 264
MPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVR++N PM
Sbjct: 79 MPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRKRNQPM 138
Query: 265 TPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGF 324
TPEAV+ NW KICDF NASKP+SIQESTG IIEVL KIDSEG +S NHT + S SGF
Sbjct: 139 TPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLHKIDSEG-ISQNHTGQVASADASGF 197
Query: 325 AGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQK 384
AG +G KLP FS +YTEL+ IMYALGVGAS+K+PKDLKF+YEGS+DFSCLPTFGVI+ QK
Sbjct: 198 AGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDLKFVYEGSADFSCLPTFGVIVAQK 257
Query: 385 SMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMD 444
S+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+G+LKCEAV+AD+LDKGSG+VI+MD
Sbjct: 258 SLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRSGELKCEAVIADILDKGSGIVIVMD 317
Query: 445 VYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAAL 504
VYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K AVA+P+RPPDAVL DTTSLNQAAL
Sbjct: 318 VYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAAVAVPSRPPDAVLRDTTSLNQAAL 377
Query: 505 YRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFA 564
YRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFSAR VLQQFADNDVSRFKAIK RFA
Sbjct: 378 YRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFSARHVLQQFADNDVSRFKAIKVRFA 437
Query: 565 KPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQS 624
KPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDL PTSG SA+TPSEGG LQS
Sbjct: 438 KPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLVPTSGVSAQTPSEGGALQS 497
Query: 625 TFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAA 684
VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+ AKWTIDLK+GSG+VYQGPAKG+A
Sbjct: 498 ALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVAAKWTIDLKNGSGEVYQGPAKGSA 557
Query: 685 DTTIILSDEDFMEVVLGKLDPQ 706
DTTI +SDEDFMEVVLGKL+PQ
Sbjct: 558 DTTITISDEDFMEVVLGKLNPQ 579
>dbj|BAD51963.1| 17-beta hydroxysteroid dehydrogenase 4 [Macaca fascicularis]
Length = 499
Score = 954 bits (2466), Expect = 0.0, Method: Composition-based stats.
Identities = 473/479 (98%), Positives = 477/479 (99%), Gaps = 1/479 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVA+YDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 61 EIRRRGGKAVASYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE GVSANHTS ATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
Sbjct: 301 KIDSE-GVSANHTSHATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGSSDFSCLPTFGVIIGQKS+MGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
Sbjct: 360 LKFVYEGSSDFSCLPTFGVIIGQKSLMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK
Sbjct: 420 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 478
>dbj|BAD92169.1| hydroxysteroid (17-beta) dehydrogenase 4 variant [Homo sapiens]
Length = 471
Score = 943 bits (2438), Expect = 0.0, Method: Composition-based stats.
Identities = 460/461 (99%), Positives = 461/461 (100%)
Query: 247 LRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEG 306
+RWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEG
Sbjct: 2 VRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEG 61
Query: 307 GVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYE 366
GVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYE
Sbjct: 62 GVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYE 121
Query: 367 GSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCE 426
GSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCE
Sbjct: 122 GSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCE 181
Query: 427 AVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPN 486
AVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPN
Sbjct: 182 AVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPN 241
Query: 487 RPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQ 546
RPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQ
Sbjct: 242 RPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQ 301
Query: 547 QFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLA 606
QFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLA
Sbjct: 302 QFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLA 361
Query: 607 PTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTI 666
PTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTI
Sbjct: 362 PTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTI 421
Query: 667 DLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQK 707
DLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQK
Sbjct: 422 DLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQK 462
>ref|XP_001087962.1| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 isoform 2
[Macaca mulatta]
Length = 498
Score = 924 bits (2387), Expect = 0.0, Method: Composition-based stats.
Identities = 463/479 (96%), Positives = 470/479 (98%), Gaps = 2/479 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVA+YDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 61 EIRRRGGKAVASYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE GVSANHTS ATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
Sbjct: 301 KIDSE-GVSANHTSHATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGSSDFSCLPTFGVIIGQKS+MGGGLAEIPGLSINFAKV+ GE ++ KPL R
Sbjct: 360 LKFVYEGSSDFSCLPTFGVIIGQKSLMGGGLAEIPGLSINFAKVI-GEPSMKAEKPLKRV 418
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK
Sbjct: 419 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 477
>emb|CAG09600.1| unnamed protein product [Tetraodon nigroviridis]
Length = 716
Score = 909 bits (2348), Expect = 0.0, Method: Composition-based stats.
Identities = 446/670 (66%), Positives = 540/670 (80%), Gaps = 1/670 (0%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
L F+GRVVLVTGAG GLGR YALAFA+RGA VVVNDLGG+ KG GK S AADKVVEEIR
Sbjct: 3 LSFEGRVVLVTGAGGGLGREYALAFAQRGASVVVNDLGGNTKGGGKSSAAADKVVEEIRA 62
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
+GGKAVA+YDSVE+GEK++++AL+ FGRIDVVVNNAGILRDRSF R SD DWD+IHR+HL
Sbjct: 63 KGGKAVASYDSVEDGEKLIQSALERFGRIDVVVNNAGILRDRSFPRTSDVDWDLIHRIHL 122
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
RGSF VTRAAW+ MKKQK+GRIIMT+SA+GIYGNFGQ+NYS+AKLGLLGLAN+LAIEGRK
Sbjct: 123 RGSFLVTRAAWDQMKKQKFGRIIMTASAAGIYGNFGQSNYSSAKLGLLGLANTLAIEGRK 182
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
NIHCNT+AP AGSR+T+TVMP DLV +LKPEYVAPLVLWLCHE C+ENGGLFEVGAGW+
Sbjct: 183 YNIHCNTVAPVAGSRLTETVMPPDLVASLKPEYVAPLVLWLCHEQCQENGGLFEVGAGWV 242
Query: 245 GKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDS 304
GKLRWER+ G IVRQKN MTPEAV+ W +ICDF +A+KP S+QES + + VLS++D+
Sbjct: 243 GKLRWERSRGQIVRQKNRAMTPEAVRDGWDRICDFTDATKPSSVQESLQAFVSVLSQVDA 302
Query: 305 EGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFI 364
G V A+ + A + + + AIGQ LP ++ + + I+YALGVG S KDP L+F+
Sbjct: 303 GGQVEASPAAAAAAPSGINPSVAIGQILPRSTFTFNHTQCILYALGVGMSTKDPDHLRFL 362
Query: 365 YEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLK 424
YEG DFSCL FGVI Q + M GL +PGL+I+ ++LHGEQYLELY+PLP +G L
Sbjct: 363 YEGHPDFSCLSHFGVIPPQAAFM-EGLTSVPGLTIDLTQMLHGEQYLELYRPLPTSGTLT 421
Query: 425 CEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAI 484
EA +ADVLDKGSG V+++DV +YS +ELIC+NQFSLF+VG+GGFGGKRTS K K ++
Sbjct: 422 SEATIADVLDKGSGAVVLLDVNTYSGEELICYNQFSLFVVGAGGFGGKRTSAKSKASLPA 481
Query: 485 PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRV 544
P R PD V+TD T+ +QAALYRLSGDWNPLHIDP+FA++ GF PILHGLC+FGF+AR V
Sbjct: 482 PKRAPDVVMTDCTTRDQAALYRLSGDWNPLHIDPSFAAIGGFKAPILHGLCSFGFAARHV 541
Query: 545 LQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVD 604
L+QFA+N+ SRFKAIK RF KPV PGQ+LQT MWKEG+RIH + V+ET D+V+S AYVD
Sbjct: 542 LKQFANNEPSRFKAIKVRFVKPVMPGQSLQTAMWKEGSRIHIECTVKETNDVVLSGAYVD 601
Query: 605 LAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKW 664
L + S + P++GG LQS VF EIGRR+K+ G E+VKKVNAVF W ITK G A W
Sbjct: 602 LHQAAEASPEPPAQGGALQSDLVFAEIGRRIKEAGSELVKKVNAVFSWEITKEGRTAAHW 661
Query: 665 TIDLKSGSGK 674
+ L G+
Sbjct: 662 SFLLGQAEGQ 671
>ref|XP_001624936.1| predicted protein [Nematostella vectensis]
gb|EDO32836.1| predicted protein [Nematostella vectensis]
Length = 725
Score = 846 bits (2186), Expect = 0.0, Method: Composition-based stats.
Identities = 427/736 (58%), Positives = 546/736 (74%), Gaps = 18/736 (2%)
Query: 4 PLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIR 63
P+RFDGRVVLVTGAG GLGR YALAFAERGA VVVNDLGGD KG GK AADKVV+EIR
Sbjct: 5 PIRFDGRVVLVTGAGNGLGRQYALAFAERGASVVVNDLGGDTKGEGKSGRAADKVVQEIR 64
Query: 64 RRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVH 123
+GGKAVA+Y+SVE+G++VV+TA+ AFGRIDVVVNNAGILRD+S R+S+ DWD++ RVH
Sbjct: 65 AKGGKAVADYNSVEQGDQVVETAIKAFGRIDVVVNNAGILRDKSILRMSELDWDLVQRVH 124
Query: 124 LRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGR 183
L+GSF VTRAAW HMKKQK+GRIIMT+S SGIYGNFGQANYSAAKLGL+GL+N+LA EG
Sbjct: 125 LKGSFLVTRAAWPHMKKQKFGRIIMTTSTSGIYGNFGQANYSAAKLGLVGLSNTLAQEGA 184
Query: 184 KSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGW 243
K NI CN IAP AGSR+T+TVM ++++EALKPEY+APLVL+LCHESCEEN GLFE GW
Sbjct: 185 KYNIKCNAIAPVAGSRLTKTVMSDEMIEALKPEYIAPLVLYLCHESCEENAGLFETAVGW 244
Query: 244 IGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKID 303
+ RW+RT G ++R++ +TPE V+ NW+ I D+ +A P ++++ + +
Sbjct: 245 FSQTRWQRTKGKLLRKEVEFVTPEMVRDNWEGITDWTDAENPT----EASNVLQFVEDVK 300
Query: 304 SEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIK-DPKDLK 362
A A+ G ++ QK+P +YT + I+YALGVG S + D LK
Sbjct: 301 -----EARQEQENARNASPG--KSMTQKMPDAKKSYTHNDVILYALGVGVSFQEDYSHLK 353
Query: 363 FIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGK 422
F+YE DF+ LPTFG+I+GQ SMMG E+ G+ + AK+LHGEQYLE+YKPLP +G
Sbjct: 354 FLYENHEDFAALPTFGIILGQGSMMGIAGGEMAGIKFDPAKLLHGEQYLEVYKPLPTSGS 413
Query: 423 LKCEAVVADVLDKGSGVVIIMDVYSYSEKEL-ICHNQFSLFLVGSGGFGGKRTSDKVKVA 481
+ A V DVLDKG G +++++V + E+E IC NQFS++L G+GGFGGKR+SDKVK
Sbjct: 414 ITNRAEVVDVLDKGKGALVLLNVTTLDEQEEPICFNQFSIYLGGAGGFGGKRSSDKVKPV 473
Query: 482 VAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSA 541
V+ P+R PDA + + T L QAALYRLSGD+NPLH+DP FA + G KPILHGLC+ G+SA
Sbjct: 474 VSPPSRTPDASVKEKTGLTQAALYRLSGDYNPLHVDPAFAQMGGLSKPILHGLCSLGYSA 533
Query: 542 RRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNA 601
R VL+Q+A+NDVS+FKA+K RF+KPV PGQT+QT+MWKEG+R+HFQ+KV E G +VIS A
Sbjct: 534 RHVLKQYANNDVSKFKALKVRFSKPVVPGQTIQTDMWKEGSRVHFQSKVVENGTVVISGA 593
Query: 602 YVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIG 661
YVD T T PS G L+S +F E+ +R+ D P++VKKV +F WH+ KGG +
Sbjct: 594 YVDF--TELTPNIPPSSSG-LKSEALFAELKKRVSD-HPDLVKKVKGIFLWHVKKGGKVV 649
Query: 662 AKWTIDLKSGSGKVYQGPAKGAA-DTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
+ WT+DLK+ G V+ GP KG DTTI DED + + GK +PQ+ F G+LK GNI
Sbjct: 650 SSWTVDLKTPGGAVFTGPPKGGKPDTTITCEDEDLISMATGKANPQQLFMKGKLKVAGNI 709
Query: 721 MLSQKLQMILKDYAKL 736
ML+ KL + KDYAK+
Sbjct: 710 MLTMKLNQLFKDYAKI 725
>ref|XP_786662.2| PREDICTED: similar to 17-beta-hydroxysteroid dehydrogenase type 4
[Strongylocentrotus purpuratus]
ref|XP_001188817.1| PREDICTED: similar to 17-beta-hydroxysteroid dehydrogenase type 4
[Strongylocentrotus purpuratus]
Length = 696
Score = 738 bits (1905), Expect = 0.0, Method: Composition-based stats.
Identities = 392/741 (52%), Positives = 494/741 (66%), Gaps = 54/741 (7%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MG LRFDGRV LVTGAG GLG+ YAL A RGA VVVNDLGGD G GK S+AAD+VV
Sbjct: 1 MGEELRFDGRVALVTGAGGGLGKEYALLLAARGASVVVNDLGGDRAGQGKSSMAADQVVN 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR +GG AVANYDSVE+G+K+V+TALD FGRID+V+NNAGILRDRSFARISD DWD++H
Sbjct: 61 EIRSKGGNAVANYDSVEDGDKLVQTALDNFGRIDIVINNAGILRDRSFARISDMDWDLVH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMKKQK+GRIIMTSSA+G+YGNFGQ NYSAAKLGL+G++N+L+
Sbjct: 121 RVHLRGSFMVTRAAWPHMKKQKFGRIIMTSSAAGLYGNFGQTNYSAAKLGLVGMSNTLSR 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG K NI CNTIAP A SR+T+ +MP D+ E LKP+YVAP+V +L HE C+ GG++E G
Sbjct: 181 EGIKYNILCNTIAPMAASRLTEDIMPPDIFEKLKPDYVAPMVAYLSHEECQSTGGIYECG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGW A K W++ Q S++ +L
Sbjct: 241 AGW------------------------AAKLRWQRTAGVNCLKPDQPYTAEQNSMMFMLE 276
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
I+ EG A+ + + + VG S P
Sbjct: 277 SIN-EGSSEADSSPSSKGDTGGDGDDGGFNPV------------------VGVSTTQPDH 317
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGL-SINFAKVLHGEQYLELYKPLPR 419
LKF++E + DF LPTFGVI ++ L +PGL SI+ ++LHGEQYLEL KPL
Sbjct: 318 LKFLFELNEDFCVLPTFGVIPSFAALQN--LTSVPGLESIDVTRILHGEQYLELKKPLDT 375
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEK-ELICHNQFSLFLVGSGGFGGKRTSDKV 478
+ KL + +V D++DK SG VII++ SY E EL+ NQ +FLVG+GGFGGKR+S +
Sbjct: 376 SAKLTNKPMVVDIVDKKSGAVIIINANSYDENNELVIVNQNVVFLVGAGGFGGKRSSPHL 435
Query: 479 KVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFG 538
K P+R PDA L + TSL+QAALYRLSGD+NPLHIDP+FA++ GF +PILHGLC+FG
Sbjct: 436 KETAKAPSRAPDASLQEKTSLDQAALYRLSGDYNPLHIDPSFAAMGGFAQPILHGLCSFG 495
Query: 539 FSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVI 598
F++R VL+Q+A+NDVS+FKAIK RF+KPV PGQT+QT+MW+EG RIHFQ+KV ETG + I
Sbjct: 496 FASRHVLKQYANNDVSKFKAIKVRFSKPVLPGQTIQTDMWQEGTRIHFQSKVVETGAVCI 555
Query: 599 SNAYVDL---APTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHIT 655
S AYVDL A + PS G L+S +F + P +VKKVN V +++IT
Sbjct: 556 SGAYVDLHGVAEQKNAAPSQPSSSG-LKSEAIFSAASGMVSG-APVLVKKVNGVIQYNIT 613
Query: 656 KGGNIGAKWTIDLKSGSGKVYQG-PAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRL 714
G + WTIDLK G G VY G P G AD T+ +SDEDF+ + G L PQ AF SG++
Sbjct: 614 SDGKVAGVWTIDLK-GQGAVYVGEPKSGKADVTVTISDEDFVALASGSLKPQTAFLSGKI 672
Query: 715 KARGNIMLSQKLQMILKDYAK 735
K +G IML QK+ + + + K
Sbjct: 673 KVKGQIMLLQKVLPMFESFMK 693
>ref|XP_974784.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
[Tribolium castaneum]
Length = 715
Score = 736 bits (1900), Expect = 0.0, Method: Composition-based stats.
Identities = 389/741 (52%), Positives = 501/741 (67%), Gaps = 38/741 (5%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
LRFDGRVV+VTGAGAGLGRAYAL F RGA VVVNDLGG G GK S AAD VVEEI+R
Sbjct: 4 LRFDGRVVVVTGAGAGLGRAYALLFGSRGAKVVVNDLGGGRHGDGKSSSAADAVVEEIKR 63
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
GG AVA+Y+SV +GEKV+KTALD FGR+DV++NNAGILRD+SFARISD+DWD++H VHL
Sbjct: 64 NGGTAVADYNSVVDGEKVIKTALDNFGRVDVLINNAGILRDKSFARISDQDWDLVHAVHL 123
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
+GSF+ T+AA+ KKQ YGRIIMTSS SG+YGNFGQANYSAAK+GL+GLA+++AIEG K
Sbjct: 124 KGSFKTTQAAFPIFKKQGYGRIIMTSSNSGLYGNFGQANYSAAKMGLVGLASTIAIEGAK 183
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
+NIHCN I P A SR+T+ ++P DL LKPE +AP+V +LCHESC ENG + E AGW
Sbjct: 184 NNIHCNVIVPTAASRLTEDILPPDLYAELKPELIAPVVAYLCHESCTENGSIIESAAGWA 243
Query: 245 GKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKID 303
GK + R+ G+++R K ++ E V+ W+K+ NA SIQE+TG+++ L +
Sbjct: 244 GKCQIIRSNGSLLRTKITDGVSVENVRDKWQKVTSMSNAEHLDSIQEATGALMTSLDSLR 303
Query: 304 SEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKF 363
S G V Y +T+ + I+YALGVGAS+K+P +LKF
Sbjct: 304 S-GEVKDEEVD---------------------VYNFTQKDIILYALGVGASLKNPNELKF 341
Query: 364 IYEGSSDFSCLPTFGVIIGQKSMMGGGLAE--IPGLSINFAKVLHGEQYLELYKPLPRAG 421
IYE DFS LPTF ++ ++M E IPG +++ A++LHGEQY+E +P+ G
Sbjct: 342 IYENDEDFSALPTFYIMPAMQAMFTSSKLESAIPGKTVSLAQILHGEQYIEFLGEVPKEG 401
Query: 422 KLKCEAVVADVLDKGSGVVIIMDVYSYSEK-ELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
KL + + +VLDKGSG I+ ++ ++ E+ L+ NQ F+VG+G FGG RT K
Sbjct: 402 KLFSKNSIVEVLDKGSGAAIVQNIETFDEQGNLLIRNQTVAFVVGAGNFGGSRTGTKAIP 461
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
+ P R PD LTD T+++QAALYRLSGD NPLHIDPN A +AGF +PILHGLCT GFS
Sbjct: 462 CQSKPPRVPDLSLTDKTTIDQAALYRLSGDTNPLHIDPNMAVVAGFKQPILHGLCTLGFS 521
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
R +++ +A D S KA KARF KPV PGQTL+ + W+EG+RIHF+T V ET +VI
Sbjct: 522 IRLLVRAYAGGDPSFVKACKARFMKPVIPGQTLRVDFWREGSRIHFETSVVETNTVVIGG 581
Query: 601 AYVDLAPTS-----GTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHIT 655
AYVDL S P+ L+S VF+ I ++K P K + VF + IT
Sbjct: 582 AYVDLNSVKVMEPINNSVSAPA----LESDAVFQFIIDQVK-ADPNKAKSIGGVFLYKIT 636
Query: 656 KGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLK 715
K G +WT+DLK + KVY+G +G TT+ ++DEDFM + GKL PQ AF G+LK
Sbjct: 637 KNGKEAKQWTMDLK--NAKVYEGAPEGKPSTTLTIADEDFMLLAQGKLQPQAAFMKGKLK 694
Query: 716 ARGNIMLSQKLQMILKDYAKL 736
GNIML+QKL ILK AKL
Sbjct: 695 ITGNIMLAQKLAPILKANAKL 715
>ref|XP_001652466.1| estradiol 17 beta-dehydrogenase [Aedes aegypti]
gb|EAT41321.1| estradiol 17 beta-dehydrogenase [Aedes aegypti]
Length = 719
Score = 729 bits (1881), Expect = 0.0, Method: Composition-based stats.
Identities = 384/738 (52%), Positives = 500/738 (67%), Gaps = 33/738 (4%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
LR+DGRVV+VTGAGAGLGR YAL F RGA VVVNDLGG+F G GK S AADKVVEEIR
Sbjct: 9 LRYDGRVVVVTGAGAGLGREYALLFGSRGAKVVVNDLGGNFHGQGK-SNAADKVVEEIRS 67
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
GG AVA+Y+SV +GEK+++TA++AFGR+DV++NNAGILRDRS ARISDEDW++IH VH+
Sbjct: 68 AGGTAVADYNSVVDGEKIIQTAMEAFGRVDVLINNAGILRDRSLARISDEDWNLIHDVHM 127
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
+GSF TRAAW MKKQ +GRIIMTSS SG+YGNFGQANYSAAKLGL+GLAN++AIEG+K
Sbjct: 128 KGSFMTTRAAWPIMKKQNFGRIIMTSSNSGVYGNFGQANYSAAKLGLVGLANTVAIEGQK 187
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
+NIHCN I P A SRMT+ ++PE L LKP+ +AP+V +LCHESCE+NG + E AGW
Sbjct: 188 NNIHCNVIVPTAASRMTEGILPEILFNELKPKLIAPVVAYLCHESCEDNGAIIESAAGWA 247
Query: 245 GKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKID 303
K+ + R G+++R + +TPE V+ W K+ D A +I E++ S++EVL K+
Sbjct: 248 TKVHFVRGKGSVLRTSIDEDVTPEYVRNVWDKVTDMSEAKHLNAIGEASLSLVEVLEKL- 306
Query: 304 SEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKF 363
EG + N + +Y + + I+YALGVGA++ D DL+F
Sbjct: 307 REGKSAENSVTE--------------------TYKFNYKDVILYALGVGATVTDESDLRF 346
Query: 364 IYEGSSDFSCLPTFGVIIGQKSMMGGGLA--EIPGLSINFAKVLHGEQYLELYKPLPRAG 421
+YE +FS LPTF ++ G S+MG L IP + +LHGEQY+EL+ +P G
Sbjct: 347 LYENHPEFSVLPTFFILPGLLSVMGSDLTAKAIPHAQFDLTNILHGEQYIELFDSVPTDG 406
Query: 422 KLKCEAVVADVLDKGSGVVIIMDVYSYSEK-ELICHNQFSLFLVGSGGFGGK-RTSDKVK 479
L + V DVLDK SG +++ S+ E L+ Q S F+VG G F GK + S +VK
Sbjct: 407 VLTTTSTVIDVLDKKSGALVVTQSESFDENGTLVARGQSSTFVVGVGNFNGKSKASSEVK 466
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
+ P R PDA + TS +QAALYRLSGD NP+HIDP+F+++AG+ PILHGLCT G
Sbjct: 467 ALMPNPKRSPDASVQIKTSRDQAALYRLSGDLNPMHIDPSFSAIAGYKTPILHGLCTMGI 526
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEG-NRIHFQTKVQETGDIVI 598
S + VL+++ ++D S FKA K RF+KPV PGQTL+ +MWKE NR+ F+T V ET V+
Sbjct: 527 SVKAVLKRYGNDDSSLFKAAKVRFSKPVLPGQTLRIDMWKEANNRVCFRTVVVETNTEVL 586
Query: 599 SNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGG 658
S AYVDL T G LQS VF I R+ + K +NAVF + IT GG
Sbjct: 587 SGAYVDLKKIVLKPNMTA--GKSLQSDAVFAGIKDRVSE-NEAKAKAINAVFLYKITDGG 643
Query: 659 NIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARG 718
+ +W +DLK + KVY+GP +G ADTT+ +SD D +++ LGKL PQ AF G+LK G
Sbjct: 644 KVSKEWVLDLK--NAKVYEGPVQGKADTTMTISDSDMVDLALGKLQPQAAFMKGKLKITG 701
Query: 719 NIMLSQKLQMILKDYAKL 736
NIML+QKL +LK AKL
Sbjct: 702 NIMLAQKLAPLLKTEAKL 719
>ref|XP_001843060.1| peroxisomal multifunctional enzyme type 2 [Culex pipiens
quinquefasciatus]
gb|EDS30335.1| peroxisomal multifunctional enzyme type 2 [Culex pipiens
quinquefasciatus]
Length = 719
Score = 725 bits (1872), Expect = 0.0, Method: Composition-based stats.
Identities = 386/740 (52%), Positives = 499/740 (67%), Gaps = 33/740 (4%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
S LR+DGRVV+VTGAGAGLGR YAL F RGA VVVNDLGG+F G GK S AADKVVEEI
Sbjct: 7 SQLRYDGRVVVVTGAGAGLGREYALLFGSRGAKVVVNDLGGNFHGQGK-SNAADKVVEEI 65
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R RGG AVA+Y+SV +G+K+++TA++AFGR+DV+VNNAGILRD+S ARISDEDW++IH V
Sbjct: 66 RERGGTAVADYNSVVDGDKIIQTAMEAFGRVDVLVNNAGILRDKSIARISDEDWNLIHDV 125
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
HL+GSF TRAAW MKKQ YGRIIMTSS SG+YGNFGQANYSAAKLGL+GLAN++AIEG
Sbjct: 126 HLKGSFVTTRAAWPIMKKQNYGRIIMTSSNSGVYGNFGQANYSAAKLGLVGLANTVAIEG 185
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 242
K++IHCN I P A SRMT+ ++PE L LKP+ +AP+V +LCHESCE+ G + E AG
Sbjct: 186 AKNDIHCNVIVPTAASRMTEGILPEILFNELKPKLIAPVVAFLCHESCEDTGAIIESAAG 245
Query: 243 WIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
W K+ + R G+++R + +TPE VK W K+ D A +I E++ ++++VL K
Sbjct: 246 WATKVHFVRGKGSVLRTSLDESVTPEYVKGVWSKVTDMSEAKHLNAIGEASLTLVDVLEK 305
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDL 361
+ GV A ++ T Y + + I+YALGVGA++ D DL
Sbjct: 306 LRE--GVPAGNSVTET-------------------YKFNYKDVILYALGVGATVTDENDL 344
Query: 362 KFIYEGSSDFSCLPTFGVIIGQKSMMGGGL--AEIPGLSINFAKVLHGEQYLELYKPLPR 419
+F+YE SDFS LPTF ++ G S+MG L + I S + +LHGEQY+EL+ +P
Sbjct: 345 RFLYENHSDFSTLPTFFILPGLLSVMGSNLTASAITHASFDLTNILHGEQYIELFDNVPT 404
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEK-ELICHNQFSLFLVGSGGFGGK-RTSDK 477
G L + V DVLDK SG ++I SY E L+ Q S F+VG G F GK + SD
Sbjct: 405 EGVLTTTSTVIDVLDKKSGALVITQSDSYDENGTLVARGQSSTFIVGVGNFNGKSKASDA 464
Query: 478 VKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTF 537
VK V P R PDA + T+ +QAALYRLSGD NP+HIDP+F+++AG+ PILHGLCT
Sbjct: 465 VKPLVPNPKRAPDASVQVKTTKDQAALYRLSGDLNPMHIDPSFSAIAGYKTPILHGLCTM 524
Query: 538 GFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEG-NRIHFQTKVQETGDI 596
G S + VL+QF +D + FKA K RF+KPV PGQTL+ +MW+E NR+ F+T V ET
Sbjct: 525 GVSVKAVLKQFGGDDSALFKAAKVRFSKPVLPGQTLRVDMWREANNRVCFRTVVVETNTE 584
Query: 597 VISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITK 656
V+S AYVD + G LQS VF I R+ + K +NAV+ + IT
Sbjct: 585 VLSGAYVDFKQI--VVKPNMTSGKSLQSDAVFAGIKERIAE-NEAKAKSINAVYLYKITD 641
Query: 657 GGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKA 716
G + +W +D K +GKVY+GP +G ADTT+ +SD D +++ LGKL PQ AF G+LK
Sbjct: 642 SGKVAKEWVLDCK--AGKVYEGPVQGKADTTMTISDADMVDLALGKLQPQTAFMKGKLKI 699
Query: 717 RGNIMLSQKLQMILKDYAKL 736
GNIML+QKL +LK AKL
Sbjct: 700 TGNIMLAQKLAPLLKTEAKL 719
>ref|XP_001606624.1| PREDICTED: similar to estradiol 17 beta-dehydrogenase [Nasonia
vitripennis]
Length = 722
Score = 723 bits (1866), Expect = 0.0, Method: Composition-based stats.
Identities = 373/733 (50%), Positives = 495/733 (67%), Gaps = 30/733 (4%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
LRFDGRVV+VTGAGAGLGRAYAL F RGA VVVNDLGG G G + AD VV+EIR+
Sbjct: 6 LRFDGRVVIVTGAGAGLGRAYALLFGSRGASVVVNDLGGGRHGDGSSTKIADTVVDEIRK 65
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
GGKAVANY++V +G+K+V+TA+DAFGRID+V+NNAGILRD+SF R+SD DWD+IH VH+
Sbjct: 66 LGGKAVANYNNVLDGDKIVQTAIDAFGRIDIVINNAGILRDKSFVRMSDTDWDLIHDVHV 125
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
+GS + TRAAW + +KQ +GR+I+TSS SG+YGNFGQANYSAAKLGL+GLAN+LAIEG K
Sbjct: 126 KGSMKTTRAAWPYFRKQNFGRVILTSSNSGLYGNFGQANYSAAKLGLVGLANTLAIEGVK 185
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
+NIH N I P A SR+T+ ++P + E LKPEY+AP+V WLCH+ C+ENG + E GW
Sbjct: 186 NNIHTNVIVPTAASRLTEDILPPEFFEQLKPEYIAPVVAWLCHDDCKENGSIIESAIGWA 245
Query: 245 GKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKID 303
GK R R+ G ++R+ N +TPEAV+ NW + D NA SIQE TG I+ L K+
Sbjct: 246 GKCRIVRSNGHLLRRDMNDIVTPEAVRDNWNTVTDMTNAKAYDSIQEVTGEIMGSLEKLK 305
Query: 304 SEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKF 363
S S+ T+ YT +AI+YALGVGA+ ++ +D+ +
Sbjct: 306 SGNSSSSQEFVMQTN--------------------YTHRDAILYALGVGATRQELRDICY 345
Query: 364 IYEGSSDFSCLPTFGVIIGQKSMMGGGLAE--IPGLSINFAKVLHGEQYLELYKPLPRAG 421
+YE +FS +P+F V G +M L + +P + ++ ++LHGEQYLE++K LP G
Sbjct: 346 LYENHENFSLIPSFYVTFGPMGLMTTTLVQDALPNVQLDPTRILHGEQYLEIHKKLPVEG 405
Query: 422 KLKCEAVVADVLDKGSGVVIIM--DVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
K++ + DVLDKG G V+++ + Y + + + NQ S F VG+GGFGG R S +
Sbjct: 406 KVESRFRIQDVLDKGKGAVVLVQYETYDVATGDKLTTNQISAFAVGAGGFGGPRNSRHLV 465
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
V P R P +T TS +QAA+YRLSGD+NPLH+D N A++AGF +PILHGLC+ GF
Sbjct: 466 PCVEPPKRKPCVSVTQKTSPDQAAIYRLSGDYNPLHMDDNIATMAGFSEPILHGLCSLGF 525
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
S R VLQ FAD D K +K RFAKPV PGQTL+T+MW+ GNRIHFQT V E VI+
Sbjct: 526 STRHVLQTFADGDPDALKTLKVRFAKPVLPGQTLRTDMWRNGNRIHFQTTVVENNSNVIT 585
Query: 600 NAYVDL--APTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKG 657
AY+DL T + S L+S VF ++ +K PE VKK+N VF + +T
Sbjct: 586 GAYMDLKEVKTPSIMSNLCSAAKNLESDAVFAQMADYVKS-HPEQVKKINGVFHYIVTSK 644
Query: 658 GNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKAR 717
G A WT+DLK VY+G +G DTT+ + D+D +++ LGKL+PQ AF G+LK +
Sbjct: 645 GEPQADWTLDLKKCV--VYKGKPEGKVDTTLTIDDKDMIQLALGKLNPQMAFMKGKLKIK 702
Query: 718 GNIMLSQKLQMIL 730
GNIML+QKL+ ++
Sbjct: 703 GNIMLTQKLKSLI 715
>ref|XP_314766.4| AGAP008667-PA [Anopheles gambiae str. PEST]
gb|EAA10131.4| AGAP008667-PA [Anopheles gambiae str. PEST]
Length = 724
Score = 707 bits (1825), Expect = 0.0, Method: Composition-based stats.
Identities = 384/740 (51%), Positives = 496/740 (67%), Gaps = 35/740 (4%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
LR+DGRVV+VTGAGAGLGR YAL FA RGA VVVNDLGG+F G GK S AADKVVEEIR
Sbjct: 12 LRYDGRVVVVTGAGAGLGREYALLFASRGAKVVVNDLGGNFHGQGK-SNAADKVVEEIRA 70
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
GG AV +Y+SV EG+K+V+TAL+ FGRIDV+VNNAGILRDRS ARISDEDW++IH VHL
Sbjct: 71 AGGVAVPDYNSVVEGDKIVQTALENFGRIDVLVNNAGILRDRSLARISDEDWNLIHDVHL 130
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
+GSF TRAAW MKKQ YGRIIMTSS SG+YGNFGQANYSAAKLGL+GLAN++AIEG K
Sbjct: 131 KGSFLTTRAAWPVMKKQNYGRIIMTSSNSGVYGNFGQANYSAAKLGLVGLANTVAIEGAK 190
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
+NI CN I P A SRMT+ ++PE L LKP+ +AP+V +LCHESCE+ G + E AGW
Sbjct: 191 NNIQCNVIVPTAASRMTEGILPEILFNELKPKLIAPVVAYLCHESCEDTGAIIESAAGWA 250
Query: 245 GKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKID 303
K+ + R G ++R + ++PE V+ W ++ D A + +I E++ S++ VL K+
Sbjct: 251 TKVHFVRGRGCVLRTSIDEDVSPEYVQQVWNRVTDMSEAKRLNAIGEASLSLVGVLEKLR 310
Query: 304 SEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKF 363
N+ + T T GF +AI+YALGVGAS+ DP DLKF
Sbjct: 311 D----GQNNENSVTETFRYGFK-----------------DAILYALGVGASVTDPTDLKF 349
Query: 364 IYEGSSDFSCLPTFGVIIGQKSMMGGGL--AEIPGLSINFAKVLHGEQYLELYKPLPRAG 421
+YE + +F+ LPTF ++ G ++MG L + I + + +LHGEQY+EL++ G
Sbjct: 350 LYENNPEFAVLPTFFILPGLLAVMGSSLTASAIKHTTFDLTNILHGEQYIELFEAPATEG 409
Query: 422 KLKCEAVVADVLDKGSGVVIIMDVYSYSEK-ELICHNQFSLFLVGSGGFGGK-RTSDKVK 479
L + V DV+DK SG ++I SY E+ L+ NQ S F+VG+G F GK + +VK
Sbjct: 410 VLTTTSTVLDVVDKKSGALVITQSDSYDEQGTLVARNQSSTFVVGAGNFNGKTKAGPEVK 469
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
V P R PDA + T NQAA+YRLSGD NP+HIDP+F+++AG+ PILHGLCT G
Sbjct: 470 PLVPNPKRSPDASVEVPTHQNQAAVYRLSGDLNPMHIDPSFSAIAGYKVPILHGLCTMGV 529
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKE-GNRIHFQTKVQETGDIVI 598
S + VL+QF +D + F+A K RF+KPV PGQTL+ +MWKE NR+ F+T V ET V+
Sbjct: 530 SVKAVLKQFGGDDPTLFRAAKVRFSKPVLPGQTLRVDMWKEPNNRVCFRTVVVETSTEVL 589
Query: 599 SNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGG 658
S AYVD T + LQS VF I R+ + K +NAVF + IT GG
Sbjct: 590 SGAYVDFKQIVIKPNMTAAV--DLQSDAVFAGIKDRVAE-NEAKAKAINAVFLYKITSGG 646
Query: 659 NIGAKWTIDLKSGSGKVYQGPAKGA--ADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKA 716
+ +W +DLK + KVY+GP +G ADTT+ ++D D +E+ LGKL PQ AF G+LK
Sbjct: 647 KVAKEWVLDLK--NAKVYEGPVQGGGKADTTMTIADGDMIELALGKLQPQTAFMKGKLKI 704
Query: 717 RGNIMLSQKLQMILKDYAKL 736
GNIML+QKL +LK AKL
Sbjct: 705 AGNIMLAQKLAPLLKTEAKL 724
>ref|XP_393475.2| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
[Apis mellifera]
Length = 704
Score = 707 bits (1824), Expect = 0.0, Method: Composition-based stats.
Identities = 360/732 (49%), Positives = 476/732 (65%), Gaps = 44/732 (6%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
L F RVV++TGAGAGLGR YAL FA RGA VVVNDLGG G G + AD VV EIR+
Sbjct: 6 LSFVNRVVIITGAGAGLGRTYALLFASRGASVVVNDLGGSRDGDGSSTKIADSVVNEIRK 65
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
GG+AVANYDSV +GEK+VKTA+DAFGRID++VNNAGILRD+SFA++ + DWD+I VHL
Sbjct: 66 NGGRAVANYDSVLDGEKIVKTAIDAFGRIDILVNNAGILRDKSFAKMLESDWDLIQNVHL 125
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
+G+F+ T+AAW + KQKYGRIIMT+S SG+YGNFGQANYSAAK+GL+GL N+LAIEG++
Sbjct: 126 KGAFKTTQAAWPYFVKQKYGRIIMTASNSGLYGNFGQANYSAAKMGLIGLTNTLAIEGKQ 185
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
NIH N I P A SR+T+ ++P D + LKPE +AP+V+WLCHE C ENG + E GW
Sbjct: 186 KNIHTNVIIPTAASRLTEDILPPDFFKELKPELIAPVVVWLCHEKCMENGSIIESALGWA 245
Query: 245 GKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKID 303
GK R+ G+ +RQ + +TPE V+ W+ I D NA SI+E TG + +
Sbjct: 246 GKCHVIRSSGSTLRQDLSSEITPEDVENKWQVITDMSNAKHFNSIEEVTGEFMTTIETTK 305
Query: 304 SEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKF 363
SE S+ + + SG + Y + I+YALGVGAS++ P D ++
Sbjct: 306 SE-------NSQPSESQNSGV----------LRHTYNYRDIILYALGVGASVQIPTDFRY 348
Query: 364 IYEGSSDFSCLPTFGVIIGQKSMMGGGLAE--IPGLSINFAKVLHGEQYLELYKPLPRAG 421
+YE S+F+ LPTF V+ + + E +P + ++ K+LHGEQY+E+YK LP
Sbjct: 349 LYENDSNFAVLPTFYVVYAPMVALEFSMYEKFLPHIELDPTKILHGEQYIEVYKQLPTEA 408
Query: 422 KLKCEAVVADVLDKGSG--VVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
++ + DV+DKG G VVI D + S ++ + Q +F++G+G F GKRTS +
Sbjct: 409 TVETRYKIVDVVDKGKGALVVIQHDTFDTSNEDKLSTGQMIIFVIGAGNFKGKRTSSYII 468
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
+ PNR PD +T TS +QAALYRLSGD NPLHID N + +AGF +PILHGLCT GF
Sbjct: 469 PTIESPNREPDTSVTQQTSQDQAALYRLSGDQNPLHIDSNMSMIAGFKRPILHGLCTLGF 528
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
S R +LQ + D S FKAIK RFAKPV PGQTL+T+MW+EGNRIHFQT E +V+
Sbjct: 529 SVRHILQTYTGGDPSLFKAIKTRFAKPVIPGQTLRTDMWQEGNRIHFQTHTVEENILVVI 588
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
N L+S VF +I +K E VKK+N VF +HI G
Sbjct: 589 NT-------------------SLESDAVFFKIAEYVKTNSDE-VKKINGVFLYHILVNGK 628
Query: 660 IGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGN 719
+ A+WT+DLK +VY+G K D T+ L D D +++ LGKL+PQ AF +LK GN
Sbjct: 629 LKAQWTLDLK--KSEVYRGEPKSKPDATLTLEDADMIQMALGKLNPQVAFVRQKLKITGN 686
Query: 720 IMLSQKLQMILK 731
IML+QKL+ +++
Sbjct: 687 IMLTQKLKTLIE 698
>ref|XP_001743502.1| predicted protein [Monosiga brevicollis MX1]
gb|EDQ92216.1| predicted protein [Monosiga brevicollis MX1]
Length = 716
Score = 695 bits (1794), Expect = 0.0, Method: Composition-based stats.
Identities = 368/740 (49%), Positives = 492/740 (66%), Gaps = 32/740 (4%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
S LRFD RVV+VTGAG GLGR YALAFA+RGA VVVNDLGG G G + AAD VV+E
Sbjct: 4 ASLLRFDERVVIVTGAGNGLGREYALAFAKRGARVVVNDLGGSVSGDGSSNRAADTVVDE 63
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR GG AVANYDSV G+ VV TA+ AFGR+DVVVNNAGILRDRSF+++++ DWDI+H+
Sbjct: 64 IRAAGGTAVANYDSVVNGQAVVDTAIKAFGRVDVVVNNAGILRDRSFSKMTEGDWDIVHQ 123
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHL+GSF V+RAAW HM+KQKYGRIIMT+S +GIYGNFGQANYSAAKLGL+GL+N+LA E
Sbjct: 124 VHLKGSFAVSRAAWPHMRKQKYGRIIMTASTAGIYGNFGQANYSAAKLGLVGLSNTLAYE 183
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K NIHCN + P AGSR++ +VMPED A+KPEYVAP+VL+LCHESCE N G++E GA
Sbjct: 184 GAKYNIHCNALVPTAGSRLSASVMPEDYANAMKPEYVAPVVLFLCHESCEANRGVYETGA 243
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
GW+ L+W+RT GA ++ ++PE V+ W I DF A S
Sbjct: 244 GWVAALKWQRTEGAKLQSAESSISPEKVRDVWDSINDFATA-----------------ST 286
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIK-DPKD 360
+DS G ++ S + A+ + P SY + A +YAL VG + P++
Sbjct: 287 VDSMNGTASLAASPEANVQQFDRKQALSHRFPTTSYVVSPRNAALYALSVGCNPSAHPEE 346
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+++YEG S+F LPTF VI Q +M G +PGL N ++LHGEQ + +++PLP
Sbjct: 347 LRYVYEGHSEFGTLPTFAVIPAQ--VMTG----LPGLRFNPMQLLHGEQSVTIHRPLPTE 400
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEK-ELICHNQFSLFLVGSGGFGGKRTSDKVK 479
GKL +A D+LDKG G + I+ V + +E EL+ N FSLF+ G G FGG T+D +
Sbjct: 401 GKLVSQASFVDILDKGRGALAILKVETRAEAGELLVTNVFSLFIRGLGNFGGPSTNDAIP 460
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
V +P P V ++ T N AALYRL+GD NPLHIDP A +AGF +PILHGLCT+G
Sbjct: 461 GNVPVPQGAPTHVFSEKTPTNLAALYRLTGDVNPLHIDPEMAKVAGFQQPILHGLCTYGT 520
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
+AR V+ Q D SR ++ RFA PV+PG+TL+T MW +RIHFQT+V E ++V+S
Sbjct: 521 AARHVIAQCLGGDASRVHVVRGRFAAPVFPGETLETSMWVRSSRIHFQTRVVERDEVVLS 580
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
+ YVD+ S +S + S K + VFE R ++ E+V++VNAVF + +
Sbjct: 581 HGYVDIV-PSSSSNPSASLPSKPEVVEVFE---RMQANLSQELVRQVNAVFTFALKSAQG 636
Query: 660 IGAKWTIDLKSGSGKVYQGPAKGAA---DTTIILSDEDFMEVVLGKLDPQKAFFSGRLKA 716
++W +DLKSG+G ++ A+ DTT+ LS++DF+++ G+L+ +AF +LK
Sbjct: 637 SDSRWVVDLKSGAGAIHPPGAQLEGLKVDTTLKLSEDDFVKLARGQLNAMQAFMQNKLKV 696
Query: 717 RGNIMLSQKLQMILKDYAKL 736
GN+ML+QKL + + AKL
Sbjct: 697 SGNMMLAQKLSGLFQTQAKL 716
>emb|CAB55552.1| Fox2 protein [Glomus mosseae]
Length = 1015
Score = 676 bits (1745), Expect = 0.0, Method: Composition-based stats.
Identities = 375/746 (50%), Positives = 503/746 (67%), Gaps = 29/746 (3%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
L+FDG+V +VTGAG GLGRAYAL + GA VVVNDLG G G S AADKVVEEIR+
Sbjct: 270 LKFDGKVAIVTGAGGGLGRAYALLLGKLGASVVVNDLGVSAHGQGATSSAADKVVEEIRQ 329
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
GGKAVANYDSVE+GEK+V+TA+ AFGR+D+++NNAGILRD+SFAR++D+DWD++ RVHL
Sbjct: 330 AGGKAVANYDSVEDGEKIVETAIKAFGRVDIIINNAGILRDKSFARMTDQDWDLVQRVHL 389
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
RG+++VT+AAW ++ KQKYGRII T+S+ G+YGNFGQANYS AKLG+LG +N+LA+EGRK
Sbjct: 390 RGTYKVTKAAWPYLTKQKYGRIINTASSVGLYGNFGQANYSTAKLGILGFSNTLALEGRK 449
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
+NI NTIAPNAG+RMT T+ P D+VEA KP+YVAP V +L HE+C G +FEVG GW+
Sbjct: 450 NNIFVNTIAPNAGTRMTATIWPPDMVEAFKPDYVAPFVSFLAHEACPSTGNVFEVGGGWV 509
Query: 245 GKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN--ASKPQSIQESTGSIIEVLSKI 302
++RW+R G I + +TPE + + I +F++ A+ P + Q++ E +
Sbjct: 510 AQVRWQRA-GGIGFPTSKALTPEDIASKIDIITNFDDGRATHPTTTQQALQQFFENFANA 568
Query: 303 D-SEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDL 361
SE G S + ++ + + A +K P + Y E + ++YALG+GA+ KDL
Sbjct: 569 QKSESGQSKSKSNNSKIDVEA----AKKRKFEPHVFEYKERDVMLYALGIGAT---RKDL 621
Query: 362 KFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAG 421
+++YE S +FS +PTFGVI L+E+ G N +LHGEQYLEL KP+P +G
Sbjct: 622 QWVYENSDNFSVIPTFGVIPAIILSNTLPLSEVLG-DFNVMMLLHGEQYLELKKPIPTSG 680
Query: 422 KLKCEAVVADVLDKGSGVVIIMDVYSYSEK-ELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
KL V D+LDKG GV I + + EK E+I NQ +LF+ G GGFGGK+T D
Sbjct: 681 KLISTPYVIDILDKGKGVSFIFGITTTDEKGEVIFENQTTLFIRGIGGFGGKKTGDDRGA 740
Query: 481 AVAI---PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTF 537
A A P R PD V+ + T+ NQAALYRLSGD+NPLHIDP+ +++ GFD PILHG+CTF
Sbjct: 741 ATASNIPPKRAPDVVVKEKTNENQAALYRLSGDYNPLHIDPSMSAMGGFDVPILHGMCTF 800
Query: 538 GFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIV 597
G S + + F ND + FK+IKAR A PV+PG+TL+T+MWK+G+++ FQT+V E I
Sbjct: 801 GISGKHIFSTFGKNDPNTFKSIKARLAAPVFPGETLETQMWKDGDKVIFQTRVVERDVIC 860
Query: 598 ISNAYVDLAPTS------GTSAKTPSEGGKL---QSTFVFEEIGRRLKDIGP----EVVK 644
I++A V+L +S G + TPS G + QS+ VFE++ L P VK
Sbjct: 861 IASAAVELRGSSASGASMGAPSATPSAGISVPGFQSSSVFEQLKAGLDAASPAERQAQVK 920
Query: 645 KVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLD 704
KV F+ +I W ID K+G G V GP+ AD TI +SD DFME+ GKL+
Sbjct: 921 KVKGSFQLNIKNAEGKEQSWYIDFKTGDGAVGIGPSPKKADATIGVSDADFMELASGKLN 980
Query: 705 PQKAFFSGRLKARGNIMLSQKLQMIL 730
QKAF SG+LK +GN+ML+ KL +L
Sbjct: 981 AQKAFMSGKLKIKGNMMLATKLGDVL 1006
Score = 299 bits (765), Expect = 6e-79, Method: Composition-based stats.
Identities = 150/287 (52%), Positives = 197/287 (68%), Gaps = 42/287 (14%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M LRFDGR V+VTGAG V+
Sbjct: 1 MAQELRFDGRTVIVTGAGG---------------------------------------VD 21
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EI + GGKAV+NY+SVE+G+K+V+TA+ AFGR+D+++NNAGILRD+SFARI+D DWD+I
Sbjct: 22 EIIKAGGKAVSNYNSVEDGDKIVETAMKAFGRVDILINNAGILRDKSFARITDSDWDLIQ 81
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
VH+RGS++VT+AAW+ +KQK+GRII T+SA+GIYGNFGQANY+ KL L+ +LA
Sbjct: 82 AVHVRGSYKVTKAAWDIFRKQKFGRIINTASAAGIYGNFGQANYT--KLALVSFTETLAK 139
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG K+NIH N IAP A SRMT++VMP D++ ALKP+YVAPLV++LCHES +ENG LFEVG
Sbjct: 140 EGAKANIHANVIAPIAASRMTESVMPPDVLAALKPDYVAPLVMYLCHESTQENGSLFEVG 199
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQS 287
AG++ KLRWER+ GA+ + + P V W +I +F N + P S
Sbjct: 200 AGFVAKLRWERSKGAVFKADD-TFLPGTVAVKWNEITEFTNPTYPTS 245
>ref|NP_573109.1| CG3415 CG3415-PA [Drosophila melanogaster]
gb|AAF48572.1| CG3415-PA [Drosophila melanogaster]
gb|AAK92917.1| GH14720p [Drosophila melanogaster]
Length = 598
Score = 619 bits (1596), Expect = e-175, Method: Composition-based stats.
Identities = 319/609 (52%), Positives = 419/609 (68%), Gaps = 33/609 (5%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
LR+DGRV +VTGAGAGLGR YAL FAERGA VVVNDLGG G G AAD VV+EIR+
Sbjct: 8 LRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADIVVDEIRK 67
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
GG+AVA+Y+SV +G KV++TA+ AFGR+D++VNNAGILRDRS + S++DW++++ VHL
Sbjct: 68 AGGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWNLVNDVHL 127
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
+GSF+ T+AA+ +MKKQ YGRIIMTSS SGIYGNFGQ NY+AAK+GL+GLAN++AIEG +
Sbjct: 128 KGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANTVAIEGAR 187
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
+N+ CN I P A SRMT+ ++P+ L LKP+ +AP+V +LCHESCE+NG E AGW
Sbjct: 188 NNVLCNVIVPTAASRMTEGILPDILFNELKPKLIAPVVAYLCHESCEDNGSYIESAAGWA 247
Query: 245 GKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKID 303
KL R GA++R + P+T E VK W + D A +I E++G+++EVL K+
Sbjct: 248 TKLHMVRGKGAVLRPSLDDPVTIEYVKDVWSNVTDMSKAKHLGAIAEASGTLLEVLEKLK 307
Query: 304 SEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKF 363
GG + ++ + E I YALG+GAS+K+ KD++F
Sbjct: 308 EGGGDAIED-----------------------AFEFNSKELITYALGIGASVKNAKDMRF 344
Query: 364 IYEGSSDFSCLPTFGVIIG---QKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+YE +DF+ +PTF V+ G Q S +P ++F+ +LHGEQYLE+ LP +
Sbjct: 345 LYENDADFAAIPTFFVLPGLLLQMSTDKLLSKALPNSQVDFSNILHGEQYLEIVDDLPTS 404
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEK-ELICHNQFSLFLVGSGGFGGKRTSDKVK 479
G L V DV+DKGSG V++ + S+ E L+ NQ + F+VG+G FGGK+ D +
Sbjct: 405 GTLLTNGKVFDVMDKGSGAVVVTNSESFDESGRLLVRNQSTTFIVGAGKFGGKK--DPIA 462
Query: 480 VAVAI---PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCT 536
V + PNR PDA + TTS +QAALYRLSGD NPLHIDP A LAGF PILHGLCT
Sbjct: 463 GVVPLQPAPNRQPDATVQYTTSEDQAALYRLSGDKNPLHIDPQMALLAGFKTPILHGLCT 522
Query: 537 FGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDI 596
GFS R VL QFADN+ + FKA+K RF+ PV PGQTL+ ++WK+G RI+F+T V ETG
Sbjct: 523 LGFSVRAVLAQFADNNPALFKAVKVRFSGPVIPGQTLRVDLWKQGTRINFRTVVVETGKE 582
Query: 597 VISNAYVDL 605
VIS AYVDL
Sbjct: 583 VISGAYVDL 591
>pdb|1ZBQ|A Chain A, Crystal Structure Of Human 17-Beta-Hydroxysteroid
Dehydrogenase Type 4 In Complex With Nad
pdb|1ZBQ|B Chain B, Crystal Structure Of Human 17-Beta-Hydroxysteroid
Dehydrogenase Type 4 In Complex With Nad
pdb|1ZBQ|C Chain C, Crystal Structure Of Human 17-Beta-Hydroxysteroid
Dehydrogenase Type 4 In Complex With Nad
pdb|1ZBQ|D Chain D, Crystal Structure Of Human 17-Beta-Hydroxysteroid
Dehydrogenase Type 4 In Complex With Nad
pdb|1ZBQ|E Chain E, Crystal Structure Of Human 17-Beta-Hydroxysteroid
Dehydrogenase Type 4 In Complex With Nad
pdb|1ZBQ|F Chain F, Crystal Structure Of Human 17-Beta-Hydroxysteroid
Dehydrogenase Type 4 In Complex With Nad
Length = 327
Score = 617 bits (1590), Expect = e-174, Method: Composition-based stats.
Identities = 304/304 (100%), Positives = 304/304 (100%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 22 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 81
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 82 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 141
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 142 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 201
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 202 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 261
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 262 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 321
Query: 301 KIDS 304
KIDS
Sbjct: 322 KIDS 325
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|NP_000405.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1308 0.0
ref|XP_001087837.1| PREDICTED: hydroxysteroid (17-beta) deh... 1277 0.0
ref|XP_531860.2| PREDICTED: similar to Peroxisomal multifun... 1251 0.0
ref|XP_859341.1| PREDICTED: similar to Peroxisomal multifun... 1243 0.0
ref|NP_001075370.1| 17 beta-hydroxysteroid dehydrogenase ty... 1241 0.0
ref|XP_859306.1| PREDICTED: similar to Peroxisomal multifun... 1241 0.0
ref|XP_517892.2| PREDICTED: hydroxysteroid (17-beta) dehydr... 1240 0.0
ref|NP_077368.2| hydroxysteroid (17-beta) dehydrogenase 4 [... 1238 0.0
gb|AAI22585.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Bo... 1237 0.0
ref|NP_001007810.1| hydroxysteroid (17-beta) dehydrogenase ... 1232 0.0
gb|AAB09724.1| peroxisomal multifunctional enzyme type II 1231 0.0
ref|NP_032318.2| hydroxysteroid (17-beta) dehydrogenase 4 [... 1229 0.0
dbj|BAE36514.1| unnamed protein product [Mus musculus] 1227 0.0
gb|AAH72472.1| Hsd17b4 protein [Rattus norvegicus] 1226 0.0
dbj|BAE27744.1| unnamed protein product [Mus musculus] 1224 0.0
emb|CAA62015.1| 17beta-hydroxysteroid dehydrogenase IV [Mus... 1221 0.0
emb|CAA64427.1| multifunctional protein 2 [Rattus norvegicus] 1220 0.0
emb|CAA73945.1| mutifunctional protein2 [Cavia porcellus] 1214 0.0
ref|NP_999471.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1208 0.0
gb|EDL09934.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 1202 0.0
gb|EDM14436.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 1175 0.0
dbj|BAF74749.1| hydroxysteroid (17-beta) dehydrogenase 4 [F... 1166 0.0
ref|NP_001027490.1| hypothetical protein LOC613082 [Xenopus... 1162 0.0
ref|NP_990274.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1152 0.0
ref|XP_001378211.1| PREDICTED: similar to 17beta-hydroxyste... 1143 0.0
ref|NP_001086063.1| MGC81885 protein [Xenopus laevis] >gi|4... 1141 0.0
gb|AAK27967.1|AF241285_1 17-beta-hydroxysteroid dehydrogena... 1127 0.0
ref|NP_956430.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1127 0.0
gb|AAH65945.1| Hsd17b4 protein [Danio rerio] 1123 0.0
ref|XP_001512505.1| PREDICTED: similar to 17beta-hydroxyste... 1100 0.0
gb|EAW48910.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 1052 0.0
ref|XP_001624936.1| predicted protein [Nematostella vectens... 1045 0.0
ref|XP_001088200.1| PREDICTED: hydroxysteroid (17-beta) deh... 1038 0.0
ref|XP_859266.1| PREDICTED: similar to Peroxisomal multifun... 1018 0.0
ref|XP_001606624.1| PREDICTED: similar to estradiol 17 beta... 1000 0.0
emb|CAG09600.1| unnamed protein product [Tetraodon nigrovir... 997 0.0
ref|XP_001652466.1| estradiol 17 beta-dehydrogenase [Aedes ... 988 0.0
ref|XP_393475.2| PREDICTED: similar to Peroxisomal multifun... 983 0.0
ref|XP_001843060.1| peroxisomal multifunctional enzyme type... 979 0.0
ref|XP_974784.1| PREDICTED: similar to Peroxisomal multifun... 978 0.0
emb|CAB55552.1| Fox2 protein [Glomus mosseae] 973 0.0
ref|XP_314766.4| AGAP008667-PA [Anopheles gambiae str. PEST... 970 0.0
ref|XP_786662.2| PREDICTED: similar to 17-beta-hydroxystero... 964 0.0
ref|XP_001743502.1| predicted protein [Monosiga brevicollis... 942 0.0
gb|EDM14435.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 921 0.0
dbj|BAD51963.1| 17-beta hydroxysteroid dehydrogenase 4 [Mac... 813 0.0
ref|XP_001400728.1| hypothetical protein An14g00990 [Asperg... 806 0.0
ref|NP_573109.1| CG3415 CG3415-PA [Drosophila melanogaster]... 802 0.0
ref|XP_746577.1| peroxisomal multifunctional beta-oxidation... 801 0.0
ref|XP_001262415.1| peroxisomal multifunctional beta-oxidat... 800 0.0
ref|XP_001241529.1| hypothetical protein CIMG_08692 [Coccid... 799 0.0
ref|XP_369316.1| peroxisomal hydratase-dehydrogenase-epimer... 797 0.0
ref|XP_001211399.1| acetoacetyl-CoA reductase [Aspergillus ... 796 0.0
dbj|BAD92169.1| hydroxysteroid (17-beta) dehydrogenase 4 va... 795 0.0
ref|XP_001906707.1| unnamed protein product [Podospora anse... 793 0.0
gb|EDU44349.1| peroxisomal multifunctional enzyme type 2 [P... 792 0.0
ref|XP_389819.1| FOX2_NEUCR Peroxisomal hydratase-dehydroge... 792 0.0
ref|XP_001536930.1| hypothetical protein HCAG_08039 [Ajello... 792 0.0
ref|XP_001825975.1| hypothetical protein [Aspergillus oryza... 790 0.0
ref|XP_001274833.1| peroxisomal multifunctional beta-oxidat... 790 0.0
ref|XP_962039.1| peroxisomal hydratase-dehydrogenase-epimer... 788 0.0
ref|XP_001087962.1| PREDICTED: hydroxysteroid (17-beta) deh... 788 0.0
ref|XP_001223046.1| peroxisomal hydratase-dehydrogenase-epi... 786 0.0
gb|EEH44993.1| peroxisomal multifunctional enzyme [Paracocc... 781 0.0
ref|XP_001545846.1| hypothetical protein BC1G_15684 [Botryo... 781 0.0
ref|XP_001589313.1| hypothetical protein SS1G_09947 [Sclero... 780 0.0
gb|EEH40042.1| peroxisomal multifunctional enzyme [Paracocc... 779 0.0
ref|XP_001355058.1| GA17436-PA [Drosophila pseudoobscura] >... 776 0.0
ref|XP_503980.1| hypothetical protein [Yarrowia lipolytica]... 766 0.0
ref|XP_001803860.1| hypothetical protein SNOG_13654 [Phaeos... 761 0.0
ref|XP_664715.1| hypothetical protein AN7111.2 [Aspergillus... 753 0.0
ref|XP_756297.1| hypothetical protein UM00150.1 [Ustilago m... 749 0.0
ref|XP_001880676.1| multifunctional beta-oxidation protein ... 746 0.0
ref|XP_571589.1| peroxisomal hydratase-dehydrogenase-epimer... 729 0.0
ref|XP_001484143.1| hypothetical protein PGUG_03524 [Pichia... 717 0.0
ref|XP_001527383.1| peroxisomal hydratase-dehydrogenase-epi... 701 0.0
ref|XP_710072.1| peroxisomal hydratase-dehydrogenase-epimer... 697 0.0
ref|XP_001383009.1| hypothetical protein PICST_54590 [Pichi... 697 0.0
ref|XP_001642757.1| hypothetical protein Kpol_348p3 [Vander... 696 0.0
sp|P22414|FOX2_CANTR Peroxisomal hydratase-dehydrogenase-ep... 695 0.0
ref|XP_456704.1| hypothetical protein DEHA0A08778g [Debaryo... 692 0.0
gb|AAA62847.1| hydratase-dehydrogenase-epimerase 691 0.0
ref|XP_454574.1| unnamed protein product [Kluyveromyces lac... 681 0.0
ref|XP_001729772.1| hypothetical protein MGL_3316 [Malassez... 679 0.0
ref|NP_986606.1| AGL060Wp [Ashbya gossypii ATCC 10895] >gi|... 651 0.0
ref|XP_448864.1| unnamed protein product [Candida glabrata]... 646 0.0
ref|NP_012934.1| Multifunctional enzyme of the peroxisomal ... 626 e-177
gb|EDN59917.1| multifunctional beta-oxidation protein [Sacc... 625 e-177
pdb|1ZBQ|A Chain A, Crystal Structure Of Human 17-Beta-Hydr... 546 e-153
dbj|BAE90061.1| unnamed protein product [Macaca fascicularis] 529 e-148
gb|EDL09933.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 523 e-146
pdb|1GZ6|A Chain A, (3r)-Hydroxyacyl-Coa Dehydrogenase Frag... 520 e-145
pdb|1S9C|A Chain A, Crystal Structure Analysis Of The 2-Eno... 514 e-144
ref|XP_001253030.1| PREDICTED: similar to Multifunctional p... 488 e-136
prf||2018258A 17beta-estradiol dehydrogenase 477 e-132
ref|YP_001188762.1| short-chain dehydrogenase/reductase SDR... 477 e-132
ref|YP_001171638.1| probable short-chain dehydrogenase [Pse... 474 e-131
ref|YP_610072.1| oxidoreductase, short chain dehydrogenase/... 471 e-131
ref|YP_001670829.1| short-chain dehydrogenase/reductase SDR... 471 e-131
ref|YP_346635.1| Short-chain dehydrogenase/reductase SDR [P... 471 e-130
ref|YP_258092.1| oxidoreductase, short chain dehydrogenase/... 469 e-130
ref|XP_001457027.1| hypothetical protein GSPATT00022802001 ... 469 e-130
ref|NP_252117.1| probable short-chain dehydrogenases [Pseud... 469 e-130
ref|NP_791019.1| oxidoreductase, short chain dehydrogenase/... 468 e-130
gb|AAT51203.1| PA3427 [synthetic construct] 468 e-130
ref|XP_001455301.1| hypothetical protein GSPATT00021528001 ... 467 e-129
ref|YP_273346.1| oxidoreductase, short chain dehydrogenase/... 467 e-129
ref|YP_001347083.1| probable short-chain dehydrogenase [Pse... 467 e-129
ref|YP_234119.1| Short-chain dehydrogenase/reductase SDR [P... 466 e-129
ref|YP_001747689.1| short-chain dehydrogenase/reductase SDR... 466 e-129
ref|XP_001021425.1| acyl carrier protein reductase [Tetrahy... 452 e-125
ref|XP_635235.1| hypothetical protein DDB_0201628 [Dictyost... 449 e-124
ref|ZP_01615241.1| Short-chain dehydrogenase/reductase SDR ... 446 e-123
ref|YP_457088.1| probable short-chain dehydrogenase [Erythr... 446 e-123
gb|ABY59724.1| D-bifunctional protein [Toxoplasma gondii] 444 e-122
ref|NP_509146.1| DeHydrogenases, Short chain family member ... 440 e-121
ref|XP_001676977.1| Hypothetical protein CBG10899 [Caenorha... 438 e-120
ref|XP_001426526.1| hypothetical protein GSPATT00029759001 ... 436 e-120
ref|ZP_02134354.1| short-chain dehydrogenase/reductase SDR ... 436 e-120
gb|AAS21352.1| 17-beta-hydroxysteroid dehydrogenase type IV... 433 e-119
ref|ZP_02131456.1| short-chain dehydrogenase/reductase SDR ... 433 e-119
gb|EEJ95553.1| dehydrogenase of unknown specificity similar... 432 e-119
ref|YP_001529431.1| short-chain dehydrogenase/reductase SDR... 430 e-118
pdb|2CDH|S Chain S, Architecture Of The Thermomyces Lanugin... 427 e-117
ref|YP_001529430.1| short-chain dehydrogenase/reductase SDR... 425 e-117
ref|YP_692674.1| oxidoreductase [Alcanivorax borkumensis SK... 424 e-116
pdb|2ET6|A Chain A, (3r)-Hydroxyacyl-Coa Dehydrogenase Doma... 422 e-116
ref|ZP_02131455.1| short-chain dehydrogenase/reductase SDR ... 419 e-115
ref|YP_001412346.1| short-chain dehydrogenase/reductase SDR... 413 e-113
ref|XP_001440682.1| hypothetical protein GSPATT00009600001 ... 409 e-112
gb|ABI95866.1| 17-beta-hydroxysteroid dehydrogenase type 4 ... 409 e-112
ref|XP_001836311.1| hypothetical protein CC1G_06396 [Coprin... 408 e-112
ref|NP_495494.1| E04F6.3 [Caenorhabditis elegans] >gi|86133... 406 e-111
ref|YP_458654.1| possible 3-oxo-(acyl) acyl carrier protein... 406 e-111
ref|XP_001433168.1| hypothetical protein GSPATT00006270001 ... 406 e-111
ref|ZP_01103376.1| Short-chain dehydrogenase/reductase SDR ... 403 e-110
ref|ZP_01040272.1| Short-chain dehydrogenase/reductase SDR ... 402 e-110
emb|CAP31946.1| C. briggsae CBR-MAOC-1 protein [Caenorhabdi... 401 e-109
ref|ZP_01223710.1| oxidoreductase, short chain dehydrogenas... 400 e-109
ref|ZP_01864417.1| possible 3-oxo-(acyl) acyl carrier prote... 399 e-109
ref|YP_884263.1| peroxisomal multifunctional enzyme type 2 ... 399 e-109
gb|AAT47756.1| probable short-chain dehydrogenase [Mycobact... 398 e-109
ref|ZP_00952848.1| possible 3-oxo-(acyl) acyl carrier prote... 398 e-108
ref|YP_750748.1| short-chain dehydrogenase/reductase SDR [S... 397 e-108
ref|YP_884512.1| peroxisomal hydratase-dehydrogenase-epimer... 395 e-108
ref|YP_615585.1| short-chain dehydrogenase/reductase SDR [S... 395 e-108
ref|NP_334566.1| oxidoreductase, short-chain dehydrogenase/... 395 e-108
ref|NP_214662.1| PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/RE... 395 e-108
ref|NP_962501.1| hypothetical protein MAP3567 [Mycobacteriu... 394 e-107
ref|YP_756878.1| short-chain dehydrogenase/reductase SDR [M... 394 e-107
ref|ZP_01616123.1| oxidoreductase, short chain dehydrogenas... 392 e-107
ref|YP_001068385.1| short-chain dehydrogenase/reductase SDR... 391 e-106
ref|YP_367244.1| Short-chain dehydrogenase/reductase SDR [B... 391 e-106
ref|YP_001239580.1| putative 3-oxo-(acyl) acyl carrier prot... 389 e-106
ref|ZP_01519585.1| short-chain dehydrogenase/reductase SDR ... 389 e-106
ref|YP_001563493.1| short-chain dehydrogenase/reductase SDR... 389 e-106
ref|YP_001684966.1| short-chain dehydrogenase/reductase SDR... 389 e-106
ref|NP_420896.1| 3-oxoacyl-(acyl-carrier-protein) reductase... 389 e-106
ref|YP_459035.1| oxidoreductase, short chain dehydrogenase/... 388 e-106
ref|YP_950963.1| short-chain dehydrogenase/reductase SDR [M... 388 e-106
ref|YP_761498.1| oxidoreductase, short chain dehydrogenase/... 388 e-105
ref|YP_001508763.1| short-chain dehydrogenase/reductase SDR... 387 e-105
ref|YP_001205176.1| putative 3-oxo-(acyl) acyl carrier prot... 387 e-105
ref|YP_001132014.1| short-chain dehydrogenase/reductase SDR... 387 e-105
ref|NP_770600.1| probable short-chain dehydrogenase [Bradyr... 386 e-105
ref|YP_637269.1| short-chain dehydrogenase/reductase SDR [M... 386 e-105
ref|YP_486812.1| Short-chain dehydrogenase/reductase SDR [R... 385 e-105
ref|ZP_02298781.1| short-chain dehydrogenase/reductase SDR ... 385 e-105
ref|YP_167200.1| oxidoreductase, short chain dehydrogenase/... 385 e-105
ref|YP_986758.1| short-chain dehydrogenase/reductase SDR [A... 385 e-105
ref|NP_947531.1| possible 3-oxo-(acyl) acyl carrier protein... 384 e-104
ref|YP_001705327.1| Putative short-chain dehydrogenase/redu... 384 e-104
ref|YP_001888840.1| short-chain dehydrogenase/reductase SDR... 384 e-104
ref|ZP_02887245.1| short-chain dehydrogenase/reductase SDR ... 382 e-104
ref|ZP_02190724.1| MaoC-like dehydratase [alpha proteobacte... 382 e-104
ref|ZP_01225010.1| oxidoreductase, short chain dehydrogenas... 382 e-104
ref|YP_569386.1| short-chain dehydrogenase/reductase SDR [R... 382 e-104
ref|XP_001836310.1| hypothetical protein CC1G_06395 [Coprin... 381 e-103
ref|YP_497943.1| short-chain dehydrogenase/reductase SDR [N... 381 e-103
gb|EEJ94366.1| dehydrogenase of unknown specificity similar... 378 e-103
ref|YP_908150.1| short-chain type dehydrogenase/reductase [... 375 e-102
ref|XP_001900411.1| oxidoreductase, short chain dehydrogena... 375 e-102
ref|YP_532949.1| short-chain dehydrogenase/reductase SDR [R... 375 e-102
ref|YP_884196.1| peroxisomal hydratase-dehydrogenase-epimer... 374 e-101
ref|YP_781309.1| short-chain dehydrogenase/reductase SDR [R... 374 e-101
ref|ZP_01626410.1| possible 3-oxo-(acyl) acyl carrier prote... 372 e-101
ref|NP_177742.2| maoC-like dehydratase domain-containing pr... 371 e-100
ref|YP_001411770.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-b... 371 e-100
ref|ZP_00998756.1| oxidoreductase, short chain dehydrogenas... 370 e-100
ref|NP_773012.1| probable short-chain dehydrogenase [Bradyr... 368 e-100
ref|ZP_00956517.1| oxidoreductase, short chain dehydrogenas... 368 e-100
ref|YP_552039.1| MaoC-like dehydratase [Polaromonas sp. JS6... 368 e-100
ref|ZP_00963728.1| oxidoreductase, short chain dehydrogenas... 368 e-99
ref|ZP_01449443.1| oxidoreductase, short chain dehydrogenas... 364 2e-98
ref|YP_001133058.1| short-chain dehydrogenase/reductase SDR... 363 4e-98
ref|YP_001561226.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-b... 363 4e-98
ref|NP_771973.1| putative dehydrogenase [Bradyrhizobium jap... 362 5e-98
ref|NP_948531.1| MaoC-like dehydratase:Asparaginase/glutami... 362 6e-98
ref|YP_570240.1| MaoC-like dehydratase [Rhodopseudomonas pa... 362 9e-98
ref|ZP_01012181.1| oxidoreductase, short chain dehydrogenas... 360 2e-97
ref|YP_001632529.1| probable short-chain type dehydrogenase... 360 2e-97
ref|NP_946764.1| MaoC-like dehydratase [Rhodopseudomonas pa... 360 3e-97
ref|ZP_02299796.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-be... 360 3e-97
ref|ZP_01000112.1| MaoC-like dehydratase [Oceanicola batsen... 359 4e-97
ref|XP_001435177.1| hypothetical protein GSPATT00036560001 ... 359 4e-97
ref|YP_641823.1| MaoC-like dehydratase [Mycobacterium sp. M... 358 1e-96
ref|YP_485968.1| MaoC-like dehydratase [Rhodopseudomonas pa... 358 1e-96
ref|YP_782438.1| MaoC domain protein dehydratase [Rhodopseu... 357 3e-96
ref|YP_001238963.1| Putative short-chain dehydrogenase [Bra... 356 4e-96
ref|ZP_01016095.1| probable short-chain dehydrogenase [Parv... 356 5e-96
ref|YP_641564.1| short-chain dehydrogenase/reductase SDR [M... 356 5e-96
ref|ZP_01037658.1| MaoC-like dehydratase [Roseovarius sp. 2... 355 7e-96
ref|YP_001481079.1| short-chain dehydrogenase/reductase SDR... 354 1e-95
ref|YP_001508000.1| short-chain dehydrogenase/reductase SDR... 354 1e-95
ref|NP_001063833.1| Os09g0544900 [Oryza sativa (japonica cu... 353 2e-95
ref|YP_984452.1| MaoC domain protein dehydratase [Acidovora... 353 3e-95
ref|NP_962444.1| hypothetical protein MAP3510 [Mycobacteriu... 353 3e-95
ref|NP_249714.1| probable short-chain dehydrogenase [Pseudo... 353 4e-95
ref|YP_001206284.1| putative dehydratase (MaoC-like) [Brady... 352 5e-95
gb|AAT51173.1| PA1023 [synthetic construct] 352 5e-95
ref|YP_001204639.1| Putative short-chain dehydrogenase [Bra... 352 7e-95
ref|YP_792247.1| probable short-chain dehydrogenase [Pseudo... 352 7e-95
ref|YP_533245.1| MaoC-like dehydratase [Rhodopseudomonas pa... 352 9e-95
ref|ZP_02303261.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-be... 351 1e-94
ref|NP_769597.1| putative short-chain dehydrogenase [Bradyr... 350 2e-94
ref|ZP_00964987.1| COG1028: Dehydrogenases with different s... 350 3e-94
ref|YP_890168.1| putative peroxisomal multifunctional enzym... 350 3e-94
ref|YP_889858.1| oxidoreductase, short chain dehydrogenase/... 349 4e-94
ref|YP_002781638.1| putative enoyl-CoA hydratase [Rhodococc... 349 6e-94
ref|YP_568274.1| MaoC-like dehydratase [Rhodopseudomonas pa... 349 6e-94
ref|YP_001629828.1| putative acyl dehydratase [Bordetella p... 348 8e-94
ref|YP_780721.1| short-chain dehydrogenase/reductase SDR [R... 348 1e-93
ref|NP_338187.1| MaoC family protein [Mycobacterium tubercu... 348 1e-93
ref|NP_773013.1| hypothetical protein bll6373 [Bradyrhizobi... 347 1e-93
ref|NP_857207.1| PROBABLE DEHYDROGENASE [Mycobacterium bovi... 347 2e-93
ref|ZP_01520456.1| MaoC-like dehydratase [Comamonas testost... 347 2e-93
ref|YP_001132788.1| MaoC domain protein dehydratase [Mycoba... 347 2e-93
ref|YP_726617.1| short chain dehydrogenase [Ralstonia eutro... 347 2e-93
ref|YP_792252.1| hypothetical protein PA14_51160 [Pseudomon... 346 4e-93
ref|NP_249709.1| hypothetical protein PA1018 [Pseudomonas a... 346 4e-93
ref|YP_002768427.1| oxidoreductase [Rhodococcus erythropoli... 346 4e-93
ref|YP_704475.1| 2-Enoyl acyl-CoA hydratase [Rhodococcus sp... 346 4e-93
ref|YP_552038.1| short-chain dehydrogenase/reductase SDR [P... 346 4e-93
ref|YP_955738.1| short-chain dehydrogenase/reductase SDR [M... 346 4e-93
ref|ZP_00964979.1| COG2030: Acyl dehydratase [Pseudomonas a... 345 6e-93
ref|YP_487195.1| Short-chain dehydrogenase/reductase SDR [R... 345 7e-93
ref|ZP_02300115.1| short-chain dehydrogenase/reductase SDR ... 345 7e-93
ref|ZP_01364378.1| hypothetical protein PaerPA_01001485 [Ps... 345 9e-93
ref|YP_367018.1| MaoC-like dehydratase [Burkholderia sp. 38... 345 9e-93
ref|YP_705752.1| possible MaoC family dehydratase [Rhodococ... 345 1e-92
gb|ABW74860.1| 2-enoyl acyl-CoA hydratase [Rhodococcus eryt... 344 1e-92
ref|YP_001349713.1| oxidoreductase, short chain dehydrogena... 344 1e-92
ref|NP_947120.1| putative dehydrogenase [Rhodopseudomonas p... 344 2e-92
ref|YP_585946.1| MaoC-like dehydratase [Ralstonia metallidu... 343 3e-92
ref|YP_569014.1| short-chain dehydrogenase/reductase SDR [R... 343 4e-92
ref|ZP_01001040.1| putative dehydrogenase [Oceanicola batse... 342 8e-92
ref|YP_956015.1| MaoC domain protein dehydratase [Mycobacte... 341 1e-91
ref|YP_001701360.1| Probable short-chain dehydrogenase/redu... 341 1e-91
ref|YP_884321.1| oxidoreductase, short chain dehydrogenase/... 340 3e-91
ref|YP_298036.1| Short-chain dehydrogenase/reductase SDR [R... 340 3e-91
ref|NP_771972.1| probable short-chain dehydrogenase [Bradyr... 340 3e-91
ref|YP_712724.1| putative short-chain dehydrogenase; putati... 340 4e-91
ref|XP_001896267.1| maoC like domain containing protein [Br... 340 4e-91
ref|YP_116668.1| hypothetical protein nfa4620 [Nocardia far... 339 4e-91
ref|YP_879903.1| MaoC like domain protein [Mycobacterium av... 339 4e-91
ref|YP_001349719.1| hypothetical protein PSPA7_4366 [Pseudo... 339 5e-91
ref|ZP_03885683.1| acyl dehydratase [Gordonia bronchialis D... 339 7e-91
ref|YP_001685634.1| short-chain dehydrogenase/reductase SDR... 338 7e-91
ref|YP_001853284.1| conserved hypothetical dehydratase (Mao... 338 1e-90
ref|NP_959463.1| UfaA2 [Mycobacterium avium subsp. paratube... 338 1e-90
ref|ZP_01037648.1| putative short-chain dehydrogenase [Rose... 337 2e-90
ref|YP_587648.1| MaoC-like dehydratase [Ralstonia metallidu... 336 3e-90
ref|YP_641841.1| short chain dehydrogenase [Mycobacterium s... 336 4e-90
ref|XP_001455573.1| hypothetical protein GSPATT00003144001 ... 336 4e-90
ref|YP_001628977.1| probable short-chain type dehydrogenase... 336 4e-90
ref|YP_001263888.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-b... 336 4e-90
ref|YP_907616.1| conserved hypothetical dehydratase (MaoC-l... 335 7e-90
ref|XP_001763373.1| predicted protein [Physcomitrella paten... 335 7e-90
ref|ZP_01227959.1| putative short chain dehydrogenase famil... 335 9e-90
ref|YP_001240914.1| putative dehydratase [Bradyrhizobium sp... 335 1e-89
ref|YP_001848632.1| short-chain type dehydrogenase/reductas... 334 2e-89
ref|ZP_01000038.1| probable short-chain dehydrogenase [Ocea... 334 2e-89
gb|EEK02592.1| acyl dehydratase [Tsukamurella paurometabola... 333 2e-89
ref|YP_001206283.1| putative short-chain dehydrogenase/redu... 333 3e-89
ref|YP_713998.1| putative oxidoreductase [Frankia alni ACN1... 333 3e-89
ref|YP_001159499.1| MaoC domain protein dehydratase [Salini... 333 3e-89
ref|YP_639699.1| short-chain dehydrogenase/reductase SDR [M... 333 4e-89
ref|YP_908194.1| short-chain type dehydrogenase/reductase [... 333 4e-89
gb|EEJ96228.1| dehydrogenase of unknown specificity similar... 332 7e-89
ref|YP_496504.1| short-chain dehydrogenase/reductase SDR [N... 332 7e-89
ref|YP_001684866.1| short-chain dehydrogenase/reductase SDR... 332 7e-89
ref|XP_001425848.1| hypothetical protein GSPATT00004822001 ... 332 8e-89
ref|YP_890225.1| short chain dehydrogenase [Mycobacterium s... 332 1e-88
gb|AAG01113.1| 17-beta-hydroxysteroid dehydrogenase type 4 ... 331 1e-88
ref|ZP_01618277.1| probable short-chain dehydrogenase [mari... 331 1e-88
ref|YP_001853295.1| short-chain type dehydrogenase/reductas... 331 2e-88
ref|YP_001135414.1| short-chain dehydrogenase/reductase SDR... 330 2e-88
ref|YP_001240913.1| putative short-chain dehydrogenase/redu... 330 3e-88
ref|YP_726616.1| putative acyl dehydratase [Ralstonia eutro... 330 3e-88
ref|YP_001413075.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-b... 330 3e-88
Sequences not found previously or not previously below threshold:
>ref|NP_000405.1| hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
sp|P51659|DHB4_HUMAN Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: 3-hydroxyacyl-CoA
dehydrogenase ;
3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase ]
emb|CAA60643.1| 17beta-hydroxysteroid dehydrogenase [Homo sapiens]
gb|AAD08652.1| 17-beta-hydroxysteroid dehydrogenase IV [Homo sapiens]
gb|AAH03098.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
gb|EAW48911.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Homo
sapiens]
gb|ABM82792.1| hydroxysteroid (17-beta) dehydrogenase 4 [synthetic construct]
gb|ABM85981.1| hydroxysteroid (17-beta) dehydrogenase 4 [synthetic construct]
Length = 736
Score = 1308 bits (3385), Expect = 0.0, Method: Composition-based stats.
Identities = 736/736 (100%), Positives = 736/736 (100%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
Sbjct: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
Sbjct: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
Sbjct: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI
Sbjct: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
Sbjct: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 721 MLSQKLQMILKDYAKL 736
>ref|XP_001087837.1| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 isoform 1
[Macaca mulatta]
Length = 734
Score = 1277 bits (3306), Expect = 0.0, Method: Composition-based stats.
Identities = 716/736 (97%), Positives = 725/736 (98%), Gaps = 2/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVA+YDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 61 EIRRRGGKAVASYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE GVSANHTS ATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
Sbjct: 301 KIDSE-GVSANHTSHATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGSSDFSCLPTFGVIIGQKS+MGGGLAEIPGLSINFAKV+ GE ++ KPL R
Sbjct: 360 LKFVYEGSSDFSCLPTFGVIIGQKSLMGGGLAEIPGLSINFAKVI-GEPSMKAEKPLKRV 418
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
Sbjct: 419 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 478
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 479 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 538
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
ARR+LQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 539 ARRILQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 598
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDLAPTS TSAKTPSEGGKLQST VFEEIGRRLKD+GPEVVKKVNAVFEWHITKGGNI
Sbjct: 599 AYVDLAPTSDTSAKTPSEGGKLQSTLVFEEIGRRLKDVGPEVVKKVNAVFEWHITKGGNI 658
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
Sbjct: 659 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 718
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 719 MLSQKLQMILKDYAKL 734
>ref|XP_531860.2| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 2 [Canis familiaris]
Length = 737
Score = 1251 bits (3237), Expect = 0.0, Method: Composition-based stats.
Identities = 643/737 (87%), Positives = 683/737 (92%), Gaps = 1/737 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGS-LAADKVV 59
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+ IDS+GGVS NHTS A STATS FAGAIG K PPFS AYTELE IMYALGVGAS+K+PK
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPK 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
D+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPR
Sbjct: 361 DMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPR 420
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
AG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDKVK
Sbjct: 421 AGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVK 480
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGF
Sbjct: 481 ATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGF 540
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVIS
Sbjct: 541 SARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVIS 600
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
NAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGN
Sbjct: 601 NAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGN 660
Query: 660 IGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGN 719
I AKWTIDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKARGN
Sbjct: 661 IAAKWTIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKARGN 720
Query: 720 IMLSQKLQMILKDYAKL 736
IMLSQKLQMILKDYAKL
Sbjct: 721 IMLSQKLQMILKDYAKL 737
>ref|XP_859341.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 5 [Canis familiaris]
Length = 739
Score = 1243 bits (3218), Expect = 0.0, Method: Composition-based stats.
Identities = 641/739 (86%), Positives = 681/739 (92%), Gaps = 3/739 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGS-LAADKVV 59
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVSANHTSRATSTATSGFA--GAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
+ IDS+GGVS NHTS A STATS GAIG K PPFS AYTELE IMYALGVGAS+K+
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEADMAGAIGHKFPPFSSAYTELETIMYALGVGASVKE 360
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPL 417
PKD+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPL
Sbjct: 361 PKDMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPL 420
Query: 418 PRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDK 477
PRAG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDK
Sbjct: 421 PRAGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDK 480
Query: 478 VKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTF 537
VK VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTF
Sbjct: 481 VKATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTF 540
Query: 538 GFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIV 597
GFSAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIV
Sbjct: 541 GFSARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIV 600
Query: 598 ISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKG 657
ISNAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKG
Sbjct: 601 ISNAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKG 660
Query: 658 GNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKAR 717
GNI AKWTIDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKAR
Sbjct: 661 GNIAAKWTIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKAR 720
Query: 718 GNIMLSQKLQMILKDYAKL 736
GNIMLSQKLQMILKDYAKL
Sbjct: 721 GNIMLSQKLQMILKDYAKL 739
>ref|NP_001075370.1| 17 beta-hydroxysteroid dehydrogenase type 4 [Equus caballus]
gb|AAS77255.1| 17 beta-hydroxysteroid dehydrogenase type 4 [Equus caballus]
Length = 735
Score = 1241 bits (3213), Expect = 0.0, Method: Composition-based stats.
Identities = 637/736 (86%), Positives = 684/736 (92%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRFDGRVVLVTGAG GLGRAYALAF ERGA VVVNDLGGD KGVGK SLAADKVVE
Sbjct: 1 MASQLRFDGRVVLVTGAGGGLGRAYALAFGERGASVVVNDLGGDMKGVGKSSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR RGGKAVA+YDSVE GEK+VKTALDAFGRIDVVVNNAGILRDRSF R+SDEDWDIIH
Sbjct: 61 EIRSRGGKAVASYDSVEAGEKIVKTALDAFGRIDVVVNNAGILRDRSFGRLSDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSASGIYGNFGQANYSAAKLGLLGL+N+LAI
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASGIYGNFGQANYSAAKLGLLGLSNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSR+TQTV PED+VEALKP+YVAPLVLWLCHESCEENG LFEVG
Sbjct: 181 EGKKNNIHCNTIAPQAGSRLTQTVFPEDVVEALKPDYVAPLVLWLCHESCEENGSLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGA+VRQ+N PMTPEAVKANWKKICDF + S PQ+IQESTG II ++S
Sbjct: 241 AGWIGKLRWERTLGALVRQRNQPMTPEAVKANWKKICDFGSVSNPQTIQESTGGIIGLVS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DS GGVS NHTS A STATSGF GAIGQKLP FS YTELEAIMYALGVGASIK+PKD
Sbjct: 301 KMDSNGGVSTNHTSHAASTATSGFVGAIGQKLPSFSSTYTELEAIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI QKS M G LA+IPGLS++FAKVLHGEQYLELYKPLPR
Sbjct: 361 MKFIYEGSSDFSCLPTFGVITAQKS-MLGELAQIPGLSLDFAKVLHGEQYLELYKPLPRT 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCE VVAD+LDKGSGVVI++DVYSYS EL+C+NQFSLFLVGSGGFGGKRTSDK+KV
Sbjct: 420 GKLKCEGVVADILDKGSGVVILLDVYSYSGNELLCYNQFSLFLVGSGGFGGKRTSDKMKV 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDA+LTDTTSLNQAALYRLSGDWNPLHIDPNF+SLAGFDKPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAILTDTTSLNQAALYRLSGDWNPLHIDPNFSSLAGFDKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFAD+DVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVISN
Sbjct: 540 ARHVLQQFADHDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTS AKTPS+GG+LQST VFEEIGRRLKDIG +VVK VNAVFEWHIT+GGN
Sbjct: 600 AYVDLVPTSDMLAKTPSKGGELQSTLVFEEIGRRLKDIGHQVVKTVNAVFEWHITEGGNT 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
A WTIDLK+GSG+VYQGPA+G+ADTT+ LSDE FMEVV GKLDPQKAFFSG+LKA+GNI
Sbjct: 660 AATWTIDLKNGSGEVYQGPARGSADTTLTLSDEHFMEVVQGKLDPQKAFFSGKLKAKGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
M+SQKLQ ILKDYAKL
Sbjct: 720 MVSQKLQKILKDYAKL 735
>ref|XP_859306.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 4 [Canis familiaris]
Length = 753
Score = 1241 bits (3211), Expect = 0.0, Method: Composition-based stats.
Identities = 642/753 (85%), Positives = 683/753 (90%), Gaps = 17/753 (2%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGS-LAADKVV 59
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+ IDS+GGVS NHTS A STATS FAGAIG K PPFS AYTELE IMYALGVGAS+K+PK
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPK 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
D+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPR
Sbjct: 361 DMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPR 420
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
AG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDKVK
Sbjct: 421 AGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVK 480
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGF
Sbjct: 481 ATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGF 540
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVIS
Sbjct: 541 SARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVIS 600
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
NAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGN
Sbjct: 601 NAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGN 660
Query: 660 IGAKWT----------------IDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKL 703
I AKW+ IDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKL
Sbjct: 661 IAAKWSNRVISFSISLFLLLTAIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKL 720
Query: 704 DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 721 DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 753
>ref|XP_517892.2| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 [Pan
troglodytes]
Length = 712
Score = 1240 bits (3210), Expect = 0.0, Method: Composition-based stats.
Identities = 695/701 (99%), Positives = 697/701 (99%)
Query: 36 VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDV 95
V +NDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDV
Sbjct: 12 VSMNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDV 71
Query: 96 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 155
VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI
Sbjct: 72 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 131
Query: 156 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKP 215
YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKP
Sbjct: 132 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKP 191
Query: 216 EYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKK 275
EYVAPLVLWLCH+SCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKK
Sbjct: 192 EYVAPLVLWLCHDSCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKK 251
Query: 276 ICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPF 335
ICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPF
Sbjct: 252 ICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPF 311
Query: 336 SYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIP 395
SYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIP
Sbjct: 312 SYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIP 371
Query: 396 GLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELIC 455
GLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELIC
Sbjct: 372 GLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELIC 431
Query: 456 HNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLH 515
HNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLH
Sbjct: 432 HNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLH 491
Query: 516 IDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQT 575
IDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQT
Sbjct: 492 IDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQT 551
Query: 576 EMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRL 635
EMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTS TSAKTPSEG KLQST VFEEIGRRL
Sbjct: 552 EMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSDTSAKTPSEGEKLQSTLVFEEIGRRL 611
Query: 636 KDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDF 695
KDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDF
Sbjct: 612 KDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDF 671
Query: 696 MEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
MEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 672 MEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 712
>ref|NP_077368.2| hydroxysteroid (17-beta) dehydrogenase 4 [Rattus norvegicus]
sp|P97852|DHB4_RAT Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: 3-hydroxyacyl-CoA
dehydrogenase ;
3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase ]
gb|AAB49519.1| 17 beta-hydroxysteroid dehydrogenase type IV; HSD IV [Rattus sp.]
Length = 735
Score = 1238 bits (3205), Expect = 0.0, Method: Composition-based stats.
Identities = 643/736 (87%), Positives = 690/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE G+S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSE-GISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>gb|AAI22585.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Bos taurus]
Length = 736
Score = 1237 bits (3203), Expect = 0.0, Method: Composition-based stats.
Identities = 631/736 (85%), Positives = 680/736 (92%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRF+GRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDF GVGKGSLAADKVVE
Sbjct: 1 MASTLRFNGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFTGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVEEGEK+VKTALDAFGRID+V+NNAGILRDRSF+RISDEDWD I
Sbjct: 61 EIRRKGGKAVANYDSVEEGEKIVKTALDAFGRIDIVINNAGILRDRSFSRISDEDWDKIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSASGIYGNFGQANY AAKLGLLGL+N LA+
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASGIYGNFGQANYCAAKLGLLGLSNCLAV 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSRMTQ+++PEDLVEALKP+YVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRMTQSILPEDLVEALKPDYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LGA+VRQ+ PMTPEAVKANW KICDF+NA+KP+SIQES GSI+E L+
Sbjct: 241 AGWIGKLRWERSLGALVRQRTQPMTPEAVKANWTKICDFDNATKPKSIQESIGSIVEALN 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KI+S G VSAN TSRATS TS FA AIG K PP +Y EL+ IMYALGVGASIK+PKD
Sbjct: 301 KINSGGEVSANPTSRATSATTSEFARAIGHKFPPLYSSYAELDTIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI+ QKS+M GGLAEIPGLSIN AK+LHGEQYLEL+KP+PRA
Sbjct: 361 MKFIYEGSSDFSCLPTFGVILAQKSIMNGGLAEIPGLSINLAKILHGEQYLELHKPIPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKL+CEA+VAD+LDKGSG+VI++DVY+YS +ELIC+NQFS+F+VGSGG GGKRTSDK K
Sbjct: 421 GKLRCEAIVADILDKGSGLVILVDVYTYSGEELICYNQFSIFVVGSGGSGGKRTSDKAKA 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETG IVISN
Sbjct: 541 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGGIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKTPSEG LQST VFEEIGRRL+ IG EVVKKV AVFEWHITKG N
Sbjct: 601 AYVDLVPASAISAKTPSEGAGLQSTLVFEEIGRRLQGIGEEVVKKVRAVFEWHITKGENT 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPAKG+AD TI LSDEDFMEVVLGKLDPQKA FSGRLKARGNI
Sbjct: 661 AAKWTIDLKTGSGKVYQGPAKGSADVTITLSDEDFMEVVLGKLDPQKAVFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
+LSQKLQMILKDYAKL
Sbjct: 721 LLSQKLQMILKDYAKL 736
>ref|NP_001007810.1| hydroxysteroid (17-beta) dehydrogenase 4 [Bos taurus]
emb|CAH17988.1| multifunctional protein 2 [Bos taurus]
Length = 736
Score = 1232 bits (3190), Expect = 0.0, Method: Composition-based stats.
Identities = 628/736 (85%), Positives = 678/736 (92%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRF+GRVVLVTGAG GLGRAYALAFAERGA VVVNDL GDF GVGKGSL+ADKVVE
Sbjct: 1 MASTLRFNGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLRGDFTGVGKGSLSADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVEEGEK+VKTALDAFGRID+V+NNAGILRDRSF+RISDEDWD I
Sbjct: 61 EIRRKGGKAVANYDSVEEGEKIVKTALDAFGRIDIVINNAGILRDRSFSRISDEDWDKIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSAS IYGNFGQANY AAKLGLLGL+N LA+
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASRIYGNFGQANYCAAKLGLLGLSNCLAV 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSRMTQ+++PEDLVEALKP+YVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRMTQSILPEDLVEALKPDYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LGA+VRQ+ PMTPEAVKANW KICDF+NA+KP+SIQES GSI+E L+
Sbjct: 241 AGWIGKLRWERSLGALVRQRTQPMTPEAVKANWTKICDFDNATKPKSIQESIGSIVEALN 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KI+S G VSAN TSRATS TS FA AIG K PP +Y EL+ IMYALGVGASIK+PKD
Sbjct: 301 KINSGGEVSANPTSRATSATTSEFARAIGHKFPPLYSSYAELDTIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI+ QKS+M GGLAEIPGLSIN AK+LHGEQYLEL+KP+PRA
Sbjct: 361 MKFIYEGSSDFSCLPTFGVILAQKSIMNGGLAEIPGLSINLAKILHGEQYLELHKPIPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKL+CEA+VAD+LDKGSG+VI++DVY+YS +ELIC+NQFS+F+VGSGG GGKRTSDK K
Sbjct: 421 GKLRCEAIVADILDKGSGLVILVDVYTYSGEELICYNQFSIFVVGSGGSGGKRTSDKAKA 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETG IVISN
Sbjct: 541 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGGIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKTPSEG LQST VFEEIGRRL+ IG EVVKKV AVFEWHITKG N
Sbjct: 601 AYVDLVPASAISAKTPSEGAGLQSTLVFEEIGRRLQGIGEEVVKKVRAVFEWHITKGENT 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPAKG+AD TI LSDEDFMEVVLGKLDPQKA FSGRLKARGNI
Sbjct: 661 AAKWTIDLKTGSGKVYQGPAKGSADVTITLSDEDFMEVVLGKLDPQKAVFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
+LSQKLQMILKDYAKL
Sbjct: 721 LLSQKLQMILKDYAKL 736
>gb|AAB09724.1| peroxisomal multifunctional enzyme type II
Length = 735
Score = 1231 bits (3186), Expect = 0.0, Method: Composition-based stats.
Identities = 640/736 (86%), Positives = 687/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDS E GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSGEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIY NFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYSNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE G+S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSE-GISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+ GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLTSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPDRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>ref|NP_032318.2| hydroxysteroid (17-beta) dehydrogenase 4 [Mus musculus]
sp|P51660|DHB4_MOUSE Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: 3-hydroxyacyl-CoA
dehydrogenase ;
3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase ]
dbj|BAB23627.1| unnamed protein product [Mus musculus]
gb|AAH22175.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Mus musculus]
dbj|BAC40317.1| unnamed protein product [Mus musculus]
dbj|BAE40862.1| unnamed protein product [Mus musculus]
dbj|BAE39029.1| unnamed protein product [Mus musculus]
dbj|BAE39222.1| unnamed protein product [Mus musculus]
gb|EDL09936.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_d [Mus
musculus]
Length = 735
Score = 1229 bits (3180), Expect = 0.0, Method: Composition-based stats.
Identities = 635/736 (86%), Positives = 687/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSE G+S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSE-GISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>dbj|BAE36514.1| unnamed protein product [Mus musculus]
Length = 735
Score = 1227 bits (3175), Expect = 0.0, Method: Composition-based stats.
Identities = 635/736 (86%), Positives = 686/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSE G+S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSE-GISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTHTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>gb|AAH72472.1| Hsd17b4 protein [Rattus norvegicus]
Length = 751
Score = 1226 bits (3174), Expect = 0.0, Method: Composition-based stats.
Identities = 642/752 (85%), Positives = 689/752 (91%), Gaps = 17/752 (2%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE G+S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSE-GISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKW----------------TIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLD 704
AKW IDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+
Sbjct: 660 AAKWMELTISFSVSSLLPANAIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLN 719
Query: 705 PQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
PQ AFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 720 PQNAFFSGRLKARGNIMLSQKLQMILKDYAKL 751
>dbj|BAE27744.1| unnamed protein product [Mus musculus]
Length = 735
Score = 1224 bits (3168), Expect = 0.0, Method: Composition-based stats.
Identities = 634/736 (86%), Positives = 686/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSE G+S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSE-GISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSG WNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGGWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>emb|CAA62015.1| 17beta-hydroxysteroid dehydrogenase IV [Mus musculus]
Length = 735
Score = 1221 bits (3161), Expect = 0.0, Method: Composition-based stats.
Identities = 633/736 (86%), Positives = 685/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTG G GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGPGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSE G+S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSE-GISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPL R+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLLRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>emb|CAA64427.1| multifunctional protein 2 [Rattus norvegicus]
Length = 734
Score = 1220 bits (3157), Expect = 0.0, Method: Composition-based stats.
Identities = 635/734 (86%), Positives = 683/734 (93%), Gaps = 1/734 (0%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
SPLRFDGRV LVTGAG GLGRAY LAFAERGALVVVNDLGGDFKGVGKGS AADKVVEEI
Sbjct: 2 SPLRFDGRVGLVTGAGGGLGRAYGLAFAERGALVVVNDLGGDFKGVGKGSSAADKVVEEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
RRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRD SF+RISDEDWDII RV
Sbjct: 62 RRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDPSFSRISDEDWDIIQRV 121
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
HLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L IEG
Sbjct: 122 HLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVIEG 181
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 242
RK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG
Sbjct: 182 RKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 241
Query: 243 WIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKI 302
WIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NAS+P+SIQESTG IIEVL KI
Sbjct: 242 WIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASEPKSIQESTGGIIEVLHKI 301
Query: 303 DSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLK 362
DSE G+S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKDLK
Sbjct: 302 DSE-GISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDLK 360
Query: 363 FIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGK 422
F+YEGS DFSCLPT GVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+G+
Sbjct: 361 FVYEGSPDFSCLPTIGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRSGE 420
Query: 423 LKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAV 482
LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K AV
Sbjct: 421 LKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAAV 480
Query: 483 AIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSAR 542
A+P+RPPDAVL DTTS+NQAALYRLSGD NPLHIDP+FA +AGF+KPILHGLCTFGFSAR
Sbjct: 481 AVPSRPPDAVLRDTTSVNQAALYRLSGDSNPLHIDPSFAGIAGFEKPILHGLCTFGFSAR 540
Query: 543 RVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY 602
VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY
Sbjct: 541 HVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY 600
Query: 603 VDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGA 662
VDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+ A
Sbjct: 601 VDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVAA 660
Query: 663 KWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIML 722
KWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNIML
Sbjct: 661 KWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNIML 720
Query: 723 SQKLQMILKDYAKL 736
SQKLQMILKDYAKL
Sbjct: 721 SQKLQMILKDYAKL 734
>emb|CAA73945.1| mutifunctional protein2 [Cavia porcellus]
Length = 735
Score = 1214 bits (3142), Expect = 0.0, Method: Composition-based stats.
Identities = 620/736 (84%), Positives = 688/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAG GLGRAYALAFAERGA V+V+DLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVIVDDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GG+AVANYDSVE GEK+VK ALDAFGRIDVVVNNAGIL RSF+RISDEDWDI+H
Sbjct: 61 EIRRKGGRAVANYDSVEAGEKIVKAALDAFGRIDVVVNNAGILTHRSFSRISDEDWDIVH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHL GSFQVTRAAW HMKKQ YGRIIMT+S++GIYGNFGQANYSAAKLGLLGL+N++AI
Sbjct: 121 RVHLWGSFQVTRAAWNHMKKQNYGRIIMTTSSAGIYGNFGQANYSAAKLGLLGLSNTIAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSR+TQTVMP+DLV+ALKPEYVAPLVLWLCH+SCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRLTQTVMPDDLVQALKPEYVAPLVLWLCHDSCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR+KN P+TPE VKANWKKICDF+NASKPQSIQESTG ++E+L
Sbjct: 241 AGWIGKLRWERTLGAIVRRKNEPVTPETVKANWKKICDFDNASKPQSIQESTGGMVEILH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE VS N TS ATSTA+ G+A AIG KLP FS +YTEL+ IMYALGVGAS+KDPK+
Sbjct: 301 KIDSEE-VSTNPTSHATSTASPGYASAIGYKLPSFSPSYTELDCIMYALGVGASVKDPKN 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEGS DFSCLPTFGVI+ QKS+ GGGLA++ GLSINFAKVLHGEQYL++YKP PRA
Sbjct: 360 LRFLYEGSPDFSCLPTFGVIVAQKSVFGGGLADVSGLSINFAKVLHGEQYLQIYKPFPRA 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCEAV+AD+LDKGSG+VI++DVY+YS +ELIC+NQFS+F+VGSGGFGGKRTS+K+KV
Sbjct: 420 GKLKCEAVIADILDKGSGLVIVLDVYAYSGEELICYNQFSVFVVGSGGFGGKRTSEKLKV 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIP+RPPDAV+TD TSL+QAALYRLSGDWNPLHIDPNFAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAIPSRPPDAVITDNTSLDQAALYRLSGDWNPLHIDPNFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVS+FKAIK RFAKPVYPGQTL+TEMWKEGNRIHFQTK+ ETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSKFKAIKVRFAKPVYPGQTLKTEMWKEGNRIHFQTKILETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKT EGG+LQST VFEEI RRLKDIG + VKKVNAVFEWHITKGGN
Sbjct: 600 AYVDLVPPSDLSAKTHPEGGELQSTRVFEEINRRLKDIGHKEVKKVNAVFEWHITKGGNT 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPA+G+ADT+I++SDEDFMEVVLGKLDPQKAFFSGRLKA+GNI
Sbjct: 660 AAKWTIDLKNGSGKVYQGPAEGSADTSILISDEDFMEVVLGKLDPQKAFFSGRLKAKGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYA L
Sbjct: 720 MLSQKLQMILKDYANL 735
>ref|NP_999471.1| hydroxysteroid (17-beta) dehydrogenase 4 [Sus scrofa]
emb|CAA55037.1| 17beta-estradiol dehydrogenase [Sus scrofa]
Length = 737
Score = 1208 bits (3126), Expect = 0.0, Method: Composition-based stats.
Identities = 623/737 (84%), Positives = 673/737 (91%), Gaps = 1/737 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S L F GRVVLVTGAG GLGR YALAFAERGA VVVNDLGGD KGVGKGSLAADKVVE
Sbjct: 1 MASMLNFYGRVVLVTGAGGGLGRTYALAFAERGASVVVNDLGGDMKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VK ALDAFGRIDVVVNNAGILRDRSF+RISDEDWD+I
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKIVKAALDAFGRIDVVVNNAGILRDRSFSRISDEDWDMIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQ +GRIIMTSSA+GIYGNFGQANYSAAKLGLLGL+NSLA+
Sbjct: 121 RVHLRGSFMVTRAAWDHMKKQNFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLSNSLAV 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNT+AP AGSRMTQ +PEDL+EALKPEYVAPLVLWLCHESCEENG +FEVG
Sbjct: 181 EGKKNNIHCNTVAPVAGSRMTQGFLPEDLIEALKPEYVAPLVLWLCHESCEENGSVFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGA+VRQKN PMTPEAVKANW KICDF+NA+KPQ IQ+S ++IE LS
Sbjct: 241 AGWIGKLRWERTLGALVRQKNQPMTPEAVKANWTKICDFDNATKPQRIQDSVSTVIEALS 300
Query: 301 KIDS-EGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
KIDS +GG+SAN+ S ATS A SG A+G K PPFS +YTE++ IMYA GVGASIK+PK
Sbjct: 301 KIDSSDGGISANNLSHATSAAPSGLVEAVGYKFPPFSSSYTEVDTIMYAFGVGASIKEPK 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
DLKFIYEG+SDFSCLPTFGVI+ QKS+ GGGLAEIPGLS+NF KVLHGE YLELYKPLP
Sbjct: 361 DLKFIYEGNSDFSCLPTFGVILAQKSLGGGGLAEIPGLSVNFTKVLHGEHYLELYKPLPN 420
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
AG LKCEAVVADVLDK SG+VI++DVYSYS KELIC+NQFS+F++GSGGFGGKRTSDK K
Sbjct: 421 AGDLKCEAVVADVLDKRSGLVILIDVYSYSGKELICYNQFSVFVMGSGGFGGKRTSDKDK 480
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
VAVAIPNRPPDA+LTDTTSLNQAALYRLSGDWNPLHIDP+FASLAGFD+PILHGLCTFGF
Sbjct: 481 VAVAIPNRPPDAILTDTTSLNQAALYRLSGDWNPLHIDPDFASLAGFDRPILHGLCTFGF 540
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VLQQ+AD DV RFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGD VIS
Sbjct: 541 SARHVLQQYADRDVLRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDTVIS 600
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
NAYVDL PTS T AK PSEGG LQS VFEEIGRRL+DIG E+VKKVNAVFEWHITKG
Sbjct: 601 NAYVDLVPTSDTLAKIPSEGGDLQSNLVFEEIGRRLQDIGQEMVKKVNAVFEWHITKGEK 660
Query: 660 IGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGN 719
I AKWTIDLK+G+GKVYQGPAKG+AD T ILSDE FMEVVLGKLDPQKAFFSGRLKARGN
Sbjct: 661 IAAKWTIDLKNGAGKVYQGPAKGSADATFILSDEVFMEVVLGKLDPQKAFFSGRLKARGN 720
Query: 720 IMLSQKLQMILKDYAKL 736
IMLSQKLQMILKDYAK+
Sbjct: 721 IMLSQKLQMILKDYAKI 737
>gb|EDL09934.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Mus
musculus]
Length = 733
Score = 1202 bits (3110), Expect = 0.0, Method: Composition-based stats.
Identities = 628/741 (84%), Positives = 680/741 (91%), Gaps = 13/741 (1%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAG-----ILRDRSFARISDED 115
EIRR+GGKAVANYDSVE GEK+VKTALD FGRI G ILRDRSF+RISDED
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRI-------GDQYFRILRDRSFSRISDED 113
Query: 116 WDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLA 175
WDIIHRVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL
Sbjct: 114 WDIIHRVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLC 173
Query: 176 NSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGG 235
N+LAIEGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGG
Sbjct: 174 NTLAIEGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGG 233
Query: 236 LFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSI 295
LFEVGAGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I
Sbjct: 234 LFEVGAGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGI 293
Query: 296 IEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASI 355
+EVL K+DSE G+S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+
Sbjct: 294 VEVLHKVDSE-GISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASV 352
Query: 356 KDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYK 415
K+PKDLKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYK
Sbjct: 353 KNPKDLKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYK 412
Query: 416 PLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTS 475
PLPR+G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS
Sbjct: 413 PLPRSGELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTS 472
Query: 476 DKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLC 535
+K+K AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLC
Sbjct: 473 EKLKAAVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLC 532
Query: 536 TFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGD 595
TFGFSAR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD
Sbjct: 533 TFGFSARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGD 592
Query: 596 IVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHIT 655
+VISNAYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHIT
Sbjct: 593 VVISNAYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHIT 652
Query: 656 KGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLK 715
KGG + AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLK
Sbjct: 653 KGGTVAAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLK 712
Query: 716 ARGNIMLSQKLQMILKDYAKL 736
ARGNIMLSQKLQMILKDYAKL
Sbjct: 713 ARGNIMLSQKLQMILKDYAKL 733
>gb|EDM14436.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Rattus
norvegicus]
Length = 708
Score = 1175 bits (3040), Expect = 0.0, Method: Composition-based stats.
Identities = 614/707 (86%), Positives = 661/707 (93%), Gaps = 1/707 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE G+S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSE-GISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQK 707
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQN 706
>dbj|BAF74749.1| hydroxysteroid (17-beta) dehydrogenase 4 [Fundulus heteroclitus]
Length = 738
Score = 1166 bits (3018), Expect = 0.0, Method: Composition-based stats.
Identities = 517/737 (70%), Positives = 608/737 (82%), Gaps = 4/737 (0%)
Query: 4 PLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIR 63
L F+GRVVLVTGAG GLG+ YALAFA RGA VVVNDLG D KG G+ S AADKVVEEIR
Sbjct: 2 SLSFEGRVVLVTGAGGGLGKEYALAFASRGASVVVNDLGVDTKGGGRSSAAADKVVEEIR 61
Query: 64 RRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVH 123
+GGKAVANYDSVE+GEK++++ALDAFGRID+VVNNAGILRDRSFAR SD DWD+IHR+H
Sbjct: 62 AKGGKAVANYDSVEDGEKLIQSALDAFGRIDIVVNNAGILRDRSFARTSDLDWDLIHRIH 121
Query: 124 LRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGR 183
LRGSF VTRAAW HMK QK+GRIIMT+SA+GIYGNFGQANYSAAKLGLLGLAN+LAIEG
Sbjct: 122 LRGSFLVTRAAWNHMKNQKFGRIIMTASAAGIYGNFGQANYSAAKLGLLGLANTLAIEGH 181
Query: 184 KSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGW 243
K NIHCNTIAP AGSR+T+TVMP DLV +LKPEYVAPLVLWLCHE C+ENGGLFEVGAGW
Sbjct: 182 KYNIHCNTIAPVAGSRLTETVMPPDLVASLKPEYVAPLVLWLCHEQCKENGGLFEVGAGW 241
Query: 244 IGKLRWERTLGAIVRQKNHPMTPEAVKA-NWKKICDFENASKPQSIQESTGSIIEVLSKI 302
IGKLRWERT G VRQ+N PMTPE V +W ICDFENA+KP ++QES S++ VLS++
Sbjct: 242 IGKLRWERTQGRTVRQRNKPMTPEGVPGTSWDAICDFENATKPANVQESLHSVVSVLSQV 301
Query: 303 DSEGGVSANHTSRATSTATSGF---AGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+S+G V AN T+ A S A+ A A+GQKLP S+++T + I+YALGVG S KDP
Sbjct: 302 ESDGDVGANPTAAAASGASGSGINPAEAVGQKLPTSSFSFTPTQCILYALGVGMSTKDPD 361
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
+L+F+YEG DFSCLPTFGVI Q + MGGGL+ +PGLSI+F +VLHGEQYLELYKPLP
Sbjct: 362 NLRFLYEGHQDFSCLPTFGVIPSQAATMGGGLSSVPGLSIDFTQVLHGEQYLELYKPLPT 421
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
+G L E VADVLDKGSG VI++DV SYS EL+C+NQFS+F+VG+ FGGKR+SDK K
Sbjct: 422 SGTLTSETTVADVLDKGSGAVILLDVNSYSGDELVCYNQFSVFVVGARRFGGKRSSDKAK 481
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
+ P R PDAV+ ++T+ +QAALYRLSGDWNPLHIDP+FA++ GF PILHGLC+FGF
Sbjct: 482 APLPPPKRAPDAVVIESTTRDQAALYRLSGDWNPLHIDPSFAAMGGFSAPILHGLCSFGF 541
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
+AR VLQ+FA+ND S+FKAIK RFAKPV+PGQ+LQTEMWKEG+RIH Q KV+ETGD+ ++
Sbjct: 542 AARHVLQRFANNDPSKFKAIKVRFAKPVFPGQSLQTEMWKEGSRIHIQCKVKETGDVALA 601
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
YVDL TS S +T +GG LQS VF EIGRR+ ++G E+VKKVNAVF W ITK G
Sbjct: 602 GGYVDLHGTSEASPETLPQGGGLQSELVFAEIGRRVTELGSELVKKVNAVFGWEITKDGK 661
Query: 660 IGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGN 719
A WTIDLK+GSG + +GP G AD T +SDEDFM+VV GKL PQKAFFSG+LK RGN
Sbjct: 662 KAADWTIDLKNGSGSLLKGPYGGKADVTFTVSDEDFMQVVTGKLPPQKAFFSGKLKVRGN 721
Query: 720 IMLSQKLQMILKDYAKL 736
IMLSQKL++ILKDYAKL
Sbjct: 722 IMLSQKLEVILKDYAKL 738
>ref|NP_001027490.1| hypothetical protein LOC613082 [Xenopus tropicalis]
gb|AAH96498.1| Hypothetical protein mgc108050 [Xenopus tropicalis]
Length = 740
Score = 1162 bits (3008), Expect = 0.0, Method: Composition-based stats.
Identities = 524/738 (71%), Positives = 622/738 (84%), Gaps = 3/738 (0%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
LRFDGRVVLVTGAG GLGR YALAFAERGA V+VNDLGGD KG GK S AADKVVEE
Sbjct: 3 SQALRFDGRVVLVTGAGGGLGRTYALAFAERGASVIVNDLGGDIKGEGKSSSAADKVVEE 62
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR +GGKAVANYDSVE GEK+V+TALDAFGRID+VVNNAGILRDRSFARISD DWDIIHR
Sbjct: 63 IRAKGGKAVANYDSVEAGEKLVQTALDAFGRIDIVVNNAGILRDRSFARISDADWDIIHR 122
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHL+G+F +TRAAW HMK QK+GRIIMTSSA+GIYGNFGQANYSAAKLGL+GL+N+LAIE
Sbjct: 123 VHLKGAFLITRAAWNHMKNQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLVGLSNTLAIE 182
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K NIH N IAP AGSR+TQTVMP+DL++ALKPEYV PLVLWLCHESC+E G LFEVGA
Sbjct: 183 GTKYNIHSNCIAPTAGSRLTQTVMPQDLLDALKPEYVTPLVLWLCHESCQETGSLFEVGA 242
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
GW+GKLRWER+LGAI+RQKN PMTPEAV+ W KI DF+NA KPQ+IQ+S + +VLS+
Sbjct: 243 GWVGKLRWERSLGAIIRQKNRPMTPEAVRDEWAKISDFDNADKPQTIQDSINPLYQVLSQ 302
Query: 302 IDSEGGVSANHTSRATSTATSGFA--GAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
DSE G+S N TS+ TS +TS AIGQKLP +Y Y+ LE I+YALGVG S +DP
Sbjct: 303 TDSEKGMSMNPTSQGTSLSTSSIDPVKAIGQKLPLTTYTYSHLEPILYALGVGMSTRDPD 362
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
LKF+YEGS DFSCLP+FGVI+ Q + M GGLA +PGL+I+F +VLHGEQYLE+YKPLP
Sbjct: 363 HLKFLYEGSEDFSCLPSFGVIVSQAAFMSGGLASVPGLNIDFTRVLHGEQYLEIYKPLPT 422
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
+G++ A VAD++DKGSG +I++DV++Y +L+C+NQFS+F+VG+GGFGGKR+S K K
Sbjct: 423 SGEMTSHATVADIMDKGSGAIILLDVHTYHGVDLVCYNQFSVFVVGAGGFGGKRSSSKAK 482
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
P+RPPD V+TD T+ +QAALYRLSGDWNPLHIDP+FA++ GF+KPILHGLC+FGF
Sbjct: 483 ATANPPSRPPDVVVTDATNADQAALYRLSGDWNPLHIDPSFAAMGGFEKPILHGLCSFGF 542
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VL+ FA+NDV++FKAIK RFAKPV PGQTLQTEMWKEGNRI QTKV++TG+I I+
Sbjct: 543 SARHVLKHFANNDVTKFKAIKVRFAKPVLPGQTLQTEMWKEGNRIFLQTKVKDTGEIAIA 602
Query: 600 NAYVDLAPTSGT-SAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGG 658
AYVDL T +K P + G LQS VF+EI RR+KD+G ++VKKVNAVF+W ITK G
Sbjct: 603 GAYVDLTSTENNLESKGPVQDGGLQSDLVFDEISRRVKDLGEQLVKKVNAVFQWDITKDG 662
Query: 659 NIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARG 718
++WTIDLKSGSG+VY+G A+G ADT+ LSDEDFME+VLG L+PQKAFF+G+LK +G
Sbjct: 663 KPASQWTIDLKSGSGEVYRGKARGRADTSFTLSDEDFMELVLGNLNPQKAFFAGKLKVKG 722
Query: 719 NIMLSQKLQMILKDYAKL 736
NIMLSQKL+MILKDYAKL
Sbjct: 723 NIMLSQKLEMILKDYAKL 740
>ref|NP_990274.1| hydroxysteroid (17-beta) dehydrogenase 4 [Gallus gallus]
gb|AAC60249.1| 17-beta-hydroxysteroid dehydrogenase type IV [Gallus gallus]
Length = 735
Score = 1152 bits (2982), Expect = 0.0, Method: Composition-based stats.
Identities = 528/738 (71%), Positives = 619/738 (83%), Gaps = 5/738 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M + LRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG GK S AADKVV
Sbjct: 1 MAAGLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGYGKSSSAADKVVS 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAV NYDSVE+GEK+VK+AL+AFGRID+V+NNAGILRDRSF RISDEDWDIIH
Sbjct: 61 EIRANGGKAVPNYDSVEDGEKLVKSALEAFGRIDIVINNAGILRDRSFVRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
R+HLRGSF VTRAAW HMK QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGL+N++AI
Sbjct: 121 RIHLRGSFLVTRAAWNHMKNQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLSNTIAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK NIHCNTIAP AGSR+TQTVMP+DL++A KPEYVAPLVLWLCHE+C ENG LFEVG
Sbjct: 181 EGRKYNIHCNTIAPTAGSRLTQTVMPQDLIDAFKPEYVAPLVLWLCHETCMENGSLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LGAIVR K+ PMTPEAV+ W+K+CDF NASKP+SIQES + + LS
Sbjct: 241 AGWIGKLRWERSLGAIVRGKDQPMTPEAVRDKWEKVCDFNNASKPRSIQESISVLNDALS 300
Query: 301 KIDSEGGVSANHT-SRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+I+S+G +S N T SR+ ++ +G++L Y YT LE I+YALGVG S KDP
Sbjct: 301 QIESQGSISMNSTNSRSVVSSAVDTTSLVGRELTTKVYKYTHLEPILYALGVGMSTKDPD 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
LKF++EGS +F CLPTFGVI Q SM G IPGL ++ AK+LHGEQYLELYKPLP
Sbjct: 361 HLKFLFEGSEEFCCLPTFGVIPAQTSMFDGVP-SIPGLDMDLAKMLHGEQYLELYKPLPT 419
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
+G+L+ + +AD+LDKGSG V+++DV +Y K+L+C+NQFSLF VG+GGFGGKRTS+K K
Sbjct: 420 SGELRSVSTIADLLDKGSGAVLLIDVNTYCGKDLVCYNQFSLFFVGAGGFGGKRTSEKAK 479
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
V V P RPPDA+L+D T+ +QAALYRLSGDWNPLH+DP+FA+L GF KPILHGLCTFGF
Sbjct: 480 VTVNPPKRPPDAILSDVTTSDQAALYRLSGDWNPLHLDPSFAALGGFQKPILHGLCTFGF 539
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
+AR VL+QFA+NDV+RFKAIK RFAKPV+PGQTLQTEMWKEGNRIHFQTKV+ETGD+ I+
Sbjct: 540 AARNVLKQFANNDVTRFKAIKVRFAKPVFPGQTLQTEMWKEGNRIHFQTKVKETGDLAIA 599
Query: 600 NAYVDLAPT-SGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGG 658
YVD+ SA P+ G LQS VFEEIGRR+K++G E+V+KVNAVF+W ITK G
Sbjct: 600 GGYVDIVSALDKPSALEPTAG--LQSDLVFEEIGRRIKEVGHELVRKVNAVFQWDITKDG 657
Query: 659 NIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARG 718
+WTIDLK+GSG VYQGPA+ +ADTT LSD+DFM+VV K +PQKAFFSG+LK +G
Sbjct: 658 KTAVQWTIDLKNGSGSVYQGPARSSADTTFTLSDQDFMDVVQKKTNPQKAFFSGKLKVKG 717
Query: 719 NIMLSQKLQMILKDYAKL 736
NIMLSQKL+MILKDYAKL
Sbjct: 718 NIMLSQKLEMILKDYAKL 735
>ref|XP_001378211.1| PREDICTED: similar to 17beta-hydroxysteroid dehydrogenase
[Monodelphis domestica]
Length = 719
Score = 1143 bits (2957), Expect = 0.0, Method: Composition-based stats.
Identities = 561/700 (80%), Positives = 641/700 (91%), Gaps = 1/700 (0%)
Query: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVV 97
VNDLGGDFKGVG+ S AAD VVEEI++RGGKAVANYDSVE GEKVVKTALDAFG+ID+V+
Sbjct: 20 VNDLGGDFKGVGRSSSAADNVVEEIKKRGGKAVANYDSVEAGEKVVKTALDAFGKIDIVI 79
Query: 98 NNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYG 157
NNAGILRDRSF RISDEDWDIIH+VHLRGSFQVTRAAW+HMKKQK+GRIIMTSSASGIYG
Sbjct: 80 NNAGILRDRSFVRISDEDWDIIHKVHLRGSFQVTRAAWDHMKKQKFGRIIMTSSASGIYG 139
Query: 158 NFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEY 217
NFGQANYSAAKLGL GL+N+LAIEGRK NIHCNTIAP AGSRMT++VMP+DLV+ALKP+Y
Sbjct: 140 NFGQANYSAAKLGLAGLSNTLAIEGRKFNIHCNTIAPTAGSRMTESVMPQDLVDALKPDY 199
Query: 218 VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKIC 277
VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKN PMTPEAVKANW+KIC
Sbjct: 200 VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNQPMTPEAVKANWRKIC 259
Query: 278 DFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSY 337
DFENA+ PQ+IQEST S+IEVL+KIDS+GGVS NHTS+A S T+ F AIG KLPP ++
Sbjct: 260 DFENANHPQTIQESTASVIEVLNKIDSQGGVSMNHTSQAASATTAAFTTAIGYKLPPRTF 319
Query: 338 AYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGL 397
+YTELEAIMYALGVGAS+K+P++LKF+YEG+SDFSCLPTFGVI QK MM GGL+E+PGL
Sbjct: 320 SYTELEAIMYALGVGASVKNPENLKFVYEGNSDFSCLPTFGVIPAQKCMMDGGLSEVPGL 379
Query: 398 SINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHN 457
+I++ KVLHGEQYLELYKPLP+ G+L EA++ D+LDKGSG+VI++DVYSYS KELIC N
Sbjct: 380 TIDYTKVLHGEQYLELYKPLPKTGQLTNEAIIVDILDKGSGLVILLDVYSYSGKELICFN 439
Query: 458 QFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHID 517
QF++F+VGSGGFGGK+TSDK KV V P RPPDA+LTDTTSLNQA LYRLSGDWNPLHID
Sbjct: 440 QFTVFVVGSGGFGGKKTSDKAKVTVPPPKRPPDAILTDTTSLNQAVLYRLSGDWNPLHID 499
Query: 518 PNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEM 577
P+FASL GF+KPILHGLC+FG++AR +LQQF +NDVSRF+AIKARFAKPVYPGQTL TEM
Sbjct: 500 PSFASLGGFEKPILHGLCSFGYAARHILQQFGNNDVSRFRAIKARFAKPVYPGQTLLTEM 559
Query: 578 WKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGT-SAKTPSEGGKLQSTFVFEEIGRRLK 636
WKEGNRIHFQTKVQETGDIV+SNAYVDL PTS S K S+ G LQST VFEEIGRR+K
Sbjct: 560 WKEGNRIHFQTKVQETGDIVLSNAYVDLVPTSDVLSTKVSSKDGTLQSTLVFEEIGRRIK 619
Query: 637 DIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFM 696
D+G E+VKKVNAVF+W+ITK G A+WTIDLK+GSG++YQGPA+G+ADT+ LSDE+FM
Sbjct: 620 DVGKELVKKVNAVFQWNITKHGQTAAQWTIDLKNGSGELYQGPARGSADTSFTLSDENFM 679
Query: 697 EVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
EVVLGKL+PQKAFFSG+L+ +GNIMLSQKL+MILKD+AKL
Sbjct: 680 EVVLGKLNPQKAFFSGKLQVKGNIMLSQKLEMILKDHAKL 719
>ref|NP_001086063.1| MGC81885 protein [Xenopus laevis]
gb|AAH74145.1| MGC81885 protein [Xenopus laevis]
Length = 741
Score = 1141 bits (2952), Expect = 0.0, Method: Composition-based stats.
Identities = 524/741 (70%), Positives = 621/741 (83%), Gaps = 5/741 (0%)
Query: 1 MGSP-LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVV 59
M S LRFDGRVVLVTGAG GLGR YALAFAERGA VVVNDLGGD KG GK S AADKVV
Sbjct: 1 MDSQVLRFDGRVVLVTGAGGGLGRTYALAFAERGASVVVNDLGGDIKGEGKSSFAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V++ALDAFGRID+++NNAGILRDRSFARISD DWDII
Sbjct: 61 EEIRAKGGKAVANYDSVEAGEKLVQSALDAFGRIDIIINNAGILRDRSFARISDADWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHL+GSF +TRAAW HMK QK+GRIIMTSSA+GIYGNFGQANYSAAKLGL+GL+N+LA
Sbjct: 121 HRVHLKGSFLITRAAWNHMKNQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLVGLSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG K NI N IAP AGSR+TQTVMP+DL++ALKPEYV PLVLWLCHE C+E G LFEV
Sbjct: 181 IEGTKYNIQSNCIAPTAGSRLTQTVMPQDLLDALKPEYVTPLVLWLCHERCQETGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
GAGW+GKLRWER+LGAI+RQ N PMTPEAV+ W KICDF+NA KPQ+IQ+S + +VL
Sbjct: 241 GAGWVGKLRWERSLGAIIRQTNRPMTPEAVRDEWAKICDFDNADKPQTIQDSINPLYQVL 300
Query: 300 SKIDSEGGVSANHTSRAT--STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
S++DSE GVS N TS T S+++ A AIGQKLP Y Y+ LE I+YALGVG S +D
Sbjct: 301 SQVDSEKGVSMNPTSHGTSLSSSSIDPAKAIGQKLPVTLYKYSHLEPILYALGVGMSTRD 360
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPL 417
P LKF+YEGS DFSCLP+FGV++ Q + M GGLA +PGL+I+F +VLHGEQYLE+YKPL
Sbjct: 361 PDHLKFLYEGSEDFSCLPSFGVVVSQAAFMSGGLASVPGLNIDFTRVLHGEQYLEVYKPL 420
Query: 418 PRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDK 477
P +G++ A VAD++DKGSG +I++DV++Y +LIC+NQFS+F+VG+GGFGGKR+S K
Sbjct: 421 PTSGEMTSHATVADIMDKGSGAIILLDVHTYHGADLICYNQFSVFVVGAGGFGGKRSSSK 480
Query: 478 VKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTF 537
K P+RPPD V D T+ +QAALYRLSGDWNPLHIDP+FA+L GF++PILHGLC+F
Sbjct: 481 AKATENPPSRPPDVVEIDVTNADQAALYRLSGDWNPLHIDPSFAALGGFERPILHGLCSF 540
Query: 538 GFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIV 597
GFSAR VL+ FA+NDV++FKAIK RFAKPV PGQTLQTEMWKEGNRI QTKV+ETG+I
Sbjct: 541 GFSARHVLKHFANNDVTKFKAIKVRFAKPVLPGQTLQTEMWKEGNRIFLQTKVKETGEIA 600
Query: 598 ISNAYVDLAPTSGTS-AKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITK 656
I+ AYVDLA T +K + G LQS VFEEI RR+KD+G ++VKKVNAVF+W ITK
Sbjct: 601 IAGAYVDLASTVNNPESKAAVQDGGLQSDLVFEEISRRVKDVGGQLVKKVNAVFQWDITK 660
Query: 657 GGNIGAKWTIDLKS-GSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLK 715
G ++WTIDLKS GSG+VY+G A+G ADT+ LSDEDFME+VLGK++PQKAFF+G+LK
Sbjct: 661 DGKTASQWTIDLKSGGSGEVYRGKARGRADTSFTLSDEDFMELVLGKVNPQKAFFAGKLK 720
Query: 716 ARGNIMLSQKLQMILKDYAKL 736
+GNIMLSQKL+MILKDYAKL
Sbjct: 721 VKGNIMLSQKLEMILKDYAKL 741
>gb|AAK27967.1|AF241285_1 17-beta-hydroxysteroid dehydrogenase type 4 [Danio rerio]
Length = 725
Score = 1127 bits (2915), Expect = 0.0, Method: Composition-based stats.
Identities = 502/736 (68%), Positives = 599/736 (81%), Gaps = 11/736 (1%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M PLRFDG+VVLVTGAG GLGR YALAF +RGA V+VNDLGGD KG GK S AADKVVE
Sbjct: 1 MSVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAVIVNDLGGDIKGGGKSSAAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAVANYDSVE+GEK+++TALDAFGRIDVVVNNAGILRDRSFAR SD DWD+I
Sbjct: 61 EIRAAGGKAVANYDSVEDGEKLIQTALDAFGRIDVVVNNAGILRDRSFARTSDVDWDLIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMK+QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGLAN+LAI
Sbjct: 121 RVHLRGSFLVTRAAWNHMKQQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K NIHCNTIAP AGSR+T+TVMP DLV++LK EYVAPLVLWLCHESC+EN GLFEVG
Sbjct: 181 EGQKYNIHCNTIAPTAGSRLTETVMPPDLVQSLKAEYVAPLVLWLCHESCQENSGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LG IVRQK+ +TPEAV+ W+ ICDF NA+KP SIQES +++EVLS
Sbjct: 241 AGWIGKLRWERSLGRIVRQKSECVTPEAVRDAWRDICDFTNATKPASIQESLQTLVEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
+++ E + AN T+ AT+ A AIG LP ++ +T + I+YALGVG S +DP+
Sbjct: 301 RVEDERKIGANPTAVATNP-----AQAIGHVLPDMTFTHTHMNCILYALGVGVSSRDPQQ 355
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEG + FSCLPTFGVI Q +++G L IPGL I+F ++LHGEQYLELYKPLP +
Sbjct: 356 LQFLYEGHTHFSCLPTFGVIPAQGALLG--LGSIPGLDIDFTRLLHGEQYLELYKPLPTS 413
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G L A VADVLDKGSG++I++DV++YSE+EL+C+NQFS+F+VGSGGFGGKR S K
Sbjct: 414 GTLTSRATVADVLDKGSGMLILLDVHTYSEQELLCYNQFSVFIVGSGGFGGKRVSQKAVA 473
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
A P+RP DAV+ + TS +QAALYRLSGDWNPLHIDPNFA++ GF PILHGLC+FGF+
Sbjct: 474 PAAPPDRPADAVVVEETSKDQAALYRLSGDWNPLHIDPNFAAMGGFQSPILHGLCSFGFA 533
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VL+QFA NDVSRFKA+K RF KPVYPGQ+LQTEMWKE +R+H Q V+E+G +V+S
Sbjct: 534 ARHVLKQFAGNDVSRFKAMKVRFVKPVYPGQSLQTEMWKENSRVHIQCTVKESGAVVLSG 593
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AY+DL P + + P +LQS VF EI RR+KD G E+VKKVNAVF W IT G
Sbjct: 594 AYIDLHPAASVNTGPPQ--TELQSDLVFAEIERRIKDSGEELVKKVNAVFGWEITTDGET 651
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
WT+DLK+G G V + AK AD T +SD+DFMEVV+GKL+PQKAFF+G+LK +GNI
Sbjct: 652 RRHWTVDLKTGRGSVQRAAAK--ADVTFTVSDQDFMEVVMGKLNPQKAFFAGKLKVKGNI 709
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKL+ +LKD A+L
Sbjct: 710 MLSQKLEAVLKDQARL 725
>ref|NP_956430.1| hydroxysteroid (17-beta) dehydrogenase 4 [Danio rerio]
gb|AAN62014.1|AF439319_1 17-beta-hydroxysteroid dehydrogenase type 4 [Danio rerio]
gb|AAH44422.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Danio rerio]
gb|AAI65653.1| Hsd17b4 protein [synthetic construct]
Length = 725
Score = 1127 bits (2915), Expect = 0.0, Method: Composition-based stats.
Identities = 502/736 (68%), Positives = 599/736 (81%), Gaps = 11/736 (1%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M PLRFDG+VVLVTGAG GLGR YALAF +RGA V+VNDLGGD KG GK S AADKVVE
Sbjct: 1 MSVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAVIVNDLGGDIKGGGKSSAAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAVANYDSVE+GEK+++TALDAFGRIDVVVNNAGILRDRSFAR SD DWD+I
Sbjct: 61 EIRAAGGKAVANYDSVEDGEKLIQTALDAFGRIDVVVNNAGILRDRSFARTSDVDWDLIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMK+QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGLAN+LAI
Sbjct: 121 RVHLRGSFLVTRAAWNHMKQQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K NIHCNTIAP AGSR+T+TVMP DLV++LK EYVAPLVLWLCHESC+EN GLFEVG
Sbjct: 181 EGQKYNIHCNTIAPTAGSRLTETVMPPDLVQSLKAEYVAPLVLWLCHESCQENSGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LG IVRQK+ +TPEAV+ W+ ICDF NA+KP SIQES +++EVLS
Sbjct: 241 AGWIGKLRWERSLGRIVRQKSECVTPEAVRDAWRDICDFTNATKPASIQESLQTLVEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
+++ E + AN T+ AT+ A AIG LP ++ +T + I+YALGVG S +DP+
Sbjct: 301 RVEDERKIGANPTAVATNP-----AQAIGHVLPDMTFTHTHMNCILYALGVGVSSRDPQQ 355
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEG + FSCLPTFGVI Q +++G L IPGL I+F ++LHGEQYLELYKPLP +
Sbjct: 356 LQFLYEGHTHFSCLPTFGVIPAQGALLG--LGSIPGLDIDFTRLLHGEQYLELYKPLPTS 413
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G L A VADVLDKGSG++I++DV++YSE+EL+C+NQFS+F+VGSGGFGGKR S K
Sbjct: 414 GTLTSRATVADVLDKGSGMLILLDVHTYSEQELLCYNQFSVFIVGSGGFGGKRVSQKAVA 473
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
A P+RP DAV+ + TS +QAALYRLSGDWNPLHIDPNFA++ GF PILHGLC+FGF+
Sbjct: 474 PAAPPDRPADAVVVEETSRDQAALYRLSGDWNPLHIDPNFAAMGGFQSPILHGLCSFGFA 533
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VL+QFA NDVSRFKA+K RF KPVYPGQ+LQTEMWKE +R+H Q V+E+G +V+S
Sbjct: 534 ARHVLKQFAGNDVSRFKAMKVRFVKPVYPGQSLQTEMWKENSRVHIQCTVKESGAVVLSG 593
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AY+DL P + + P +LQS VF EI RR+KD G E+VKKVNAVF W IT G
Sbjct: 594 AYIDLHPAASVNTGPPQ--TELQSDLVFAEIERRIKDSGEELVKKVNAVFGWEITTDGET 651
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
WT+DLK+G G V + AK AD T +SD+DFMEVV+GKL+PQKAFF+G+LK +GNI
Sbjct: 652 RRHWTVDLKTGRGSVQRAAAK--ADVTFTVSDQDFMEVVMGKLNPQKAFFAGKLKVKGNI 709
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKL+ +LKD A+L
Sbjct: 710 MLSQKLEAVLKDQARL 725
>gb|AAH65945.1| Hsd17b4 protein [Danio rerio]
Length = 725
Score = 1123 bits (2905), Expect = 0.0, Method: Composition-based stats.
Identities = 501/736 (68%), Positives = 597/736 (81%), Gaps = 11/736 (1%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M PLRFDG+VVLVTGAG GLGR YALAF +RGA V+VNDLGGD KG GK S AADKVVE
Sbjct: 1 MSVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAVIVNDLGGDIKGGGKSSAAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAVANYDSVE+GEK+++TALDAFGRIDVVVNNAGILRDRSFAR SD DWD+I
Sbjct: 61 EIRAAGGKAVANYDSVEDGEKLIQTALDAFGRIDVVVNNAGILRDRSFARTSDVDWDLIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMK+QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGLAN+LAI
Sbjct: 121 RVHLRGSFLVTRAAWNHMKQQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K NIHCNTIAP AGSR+T+TVMP DLV++LK EYVAPLVLWLCHESC+EN GLFEVG
Sbjct: 181 EGQKYNIHCNTIAPTAGSRLTETVMPPDLVQSLKAEYVAPLVLWLCHESCQENSGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LG IVRQK+ +TPEAV+ W+ ICDF NA+KP SIQES +++EVLS
Sbjct: 241 AGWIGKLRWERSLGRIVRQKSECVTPEAVRDAWRDICDFTNATKPASIQESLQTLVEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
+++ E + AN T+ AT+ A AIG LP ++ +T + I+YALGVG S +DP+
Sbjct: 301 RVEDERKIEANPTAVATNP-----AQAIGHVLPDMTFTHTHMNCILYALGVGVSSRDPQQ 355
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEG + FSCLPTFGVI Q +++G L IPGL I+F ++LHGEQYLELYK LP +
Sbjct: 356 LQFLYEGHTHFSCLPTFGVIPAQGALLG--LGSIPGLDIDFTRLLHGEQYLELYKSLPTS 413
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G L A VADVLDKGSG++I++DV++YSE+EL+C+NQFS+F+VGSGGFGGKR S K
Sbjct: 414 GTLTSRATVADVLDKGSGMLILLDVHTYSEQELLCYNQFSVFIVGSGGFGGKRVSQKAVA 473
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
A P+RP DAV+ + TS +QAALYRLSGDWNPLHIDPNFA++ GF PILHGLC+FGF+
Sbjct: 474 PAAPPDRPADAVVVEETSKDQAALYRLSGDWNPLHIDPNFAAMGGFQSPILHGLCSFGFA 533
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VL+QFA NDVSRFKA+K RF KPVYPGQ+LQTEMWKE +R+H Q V+E+G +V+S
Sbjct: 534 ARHVLKQFAGNDVSRFKAMKVRFVKPVYPGQSLQTEMWKENSRVHIQCTVKESGAVVLSG 593
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AY+DL P + + P +LQS VF EI RR+KD G E+VKKVNAVF W IT G
Sbjct: 594 AYIDLHPAASVNTGPPQ--TELQSDLVFAEIERRIKDSGEELVKKVNAVFGWEITTDGET 651
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
WT+DLK+G G V + AK AD T +SD DFMEVV+GKL+PQKAFF+G+LK +GNI
Sbjct: 652 RRHWTVDLKTGRGSVQRAAAK--ADVTFTVSDRDFMEVVMGKLNPQKAFFAGKLKVKGNI 709
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKL+ +LKD A+L
Sbjct: 710 MLSQKLEAVLKDQARL 725
>ref|XP_001512505.1| PREDICTED: similar to 17beta-hydroxysteroid dehydrogenase
[Ornithorhynchus anatinus]
Length = 752
Score = 1100 bits (2846), Expect = 0.0, Method: Composition-based stats.
Identities = 503/710 (70%), Positives = 597/710 (84%), Gaps = 12/710 (1%)
Query: 39 NDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVN 98
NDLGGDFKG GK S AA KVVEEIR++GGKAVANYDSVE GEK+VK ALDAFGRID+V+N
Sbjct: 43 NDLGGDFKGEGKSSSAAAKVVEEIRKKGGKAVANYDSVEAGEKIVKAALDAFGRIDIVIN 102
Query: 99 NAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGN 158
NAGILRDRSF RISD DWDIIHRVHLRGSFQVTRAAW+HMK+Q +GRIIMTSSA+GIYGN
Sbjct: 103 NAGILRDRSFVRISDHDWDIIHRVHLRGSFQVTRAAWDHMKQQNFGRIIMTSSAAGIYGN 162
Query: 159 FGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYV 218
FGQANYSAAKLGL+GL+N+LAIEGRK NIHCN+IAP AGSR+TQTVM +D+V+ALKPEYV
Sbjct: 163 FGQANYSAAKLGLVGLSNTLAIEGRKYNIHCNSIAPTAGSRLTQTVMTQDMVDALKPEYV 222
Query: 219 APLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICD 278
APLVLWLCHESC ENGGLFEVGAGWIGKLRWERTLGAIVRQKN PMTPEAVKA+WKKICD
Sbjct: 223 APLVLWLCHESCMENGGLFEVGAGWIGKLRWERTLGAIVRQKNQPMTPEAVKADWKKICD 282
Query: 279 FENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYA 338
F+N +KP++I+ESTG ++EVLSKI+ G VS N TS+A S A S + K+ P+++
Sbjct: 283 FDNVTKPRTIEESTGGMLEVLSKIEDGGAVSMNPTSQAASVAKSQLDRVVEYKISPWTFE 342
Query: 339 YTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLS 398
Y++LE I+YAL VGAS+K+P D+KF+YE +++FSCLPTFGVI QK + G ++IPG+
Sbjct: 343 YSQLETIIYALAVGASVKNPDDMKFVYERNANFSCLPTFGVIPAQKCLSTGLFSDIPGIQ 402
Query: 399 INFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQ 458
IN K+LHGEQYLE+YK P +GKL E V+ADVLDKGSG VI+ DV +Y EKELIC+NQ
Sbjct: 403 INMEKLLHGEQYLEVYKLFPSSGKLWSEGVIADVLDKGSGSVILFDVTTYHEKELICYNQ 462
Query: 459 FSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDP 518
FSLF++GSGGFGGKRTS+KVK ++ +P+RPPDAV D TSLNQAALYRLSGDWNPLHIDP
Sbjct: 463 FSLFVIGSGGFGGKRTSEKVKPSLPVPDRPPDAVCYDVTSLNQAALYRLSGDWNPLHIDP 522
Query: 519 NFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMW 578
+FA+L GF+KPILHGLC+FGFSAR VL QFADND +RF+AIK RFAKPVYPGQTLQTEMW
Sbjct: 523 DFAALGGFEKPILHGLCSFGFSARHVLHQFADNDPARFRAIKVRFAKPVYPGQTLQTEMW 582
Query: 579 KEGNRIHFQTKVQETGDIVISNAYVDLAPTS-----------GTSAKTPSE-GGKLQSTF 626
K GNRIHFQTKV ETG+IVISNAYVDL P+S G S + PS LQS
Sbjct: 583 KNGNRIHFQTKVTETGNIVISNAYVDLVPSSDETSDNRTIKVGESTRIPSLCVEGLQSNI 642
Query: 627 VFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADT 686
+F+ IG+R+K+IG E+VKKV+AV + +ITKGG A WTIDLK+GSG+VYQGPAK
Sbjct: 643 IFDVIGQRIKEIGKELVKKVSAVIQLNITKGGKTAAIWTIDLKNGSGEVYQGPAKVPPQA 702
Query: 687 TIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
T LSDEDF+++V+G+L+P +AFF+GR+K GN++++ L MILK Y+KL
Sbjct: 703 TFTLSDEDFVKIVVGRLNPHQAFFNGRIKVEGNLIIAHNLNMILKTYSKL 752
>gb|EAW48910.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_a [Homo
sapiens]
Length = 596
Score = 1052 bits (2721), Expect = 0.0, Method: Composition-based stats.
Identities = 596/599 (99%), Positives = 596/599 (99%), Gaps = 3/599 (0%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQK IIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG
Sbjct: 1 MKKQK---IIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 57
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV
Sbjct: 58 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 117
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 317
RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT
Sbjct: 118 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 177
Query: 318 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF
Sbjct: 178 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 237
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS
Sbjct: 238 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 297
Query: 438 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 497
GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT
Sbjct: 298 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 357
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK
Sbjct: 358 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 417
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS
Sbjct: 418 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 477
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ
Sbjct: 478 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 537
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 538 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 596
>ref|XP_001624936.1| predicted protein [Nematostella vectensis]
gb|EDO32836.1| predicted protein [Nematostella vectensis]
Length = 725
Score = 1045 bits (2704), Expect = 0.0, Method: Composition-based stats.
Identities = 429/738 (58%), Positives = 545/738 (73%), Gaps = 18/738 (2%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
P+RFDGRVVLVTGAG GLGR YALAFAERGA VVVNDLGGD KG GK AADKVV+E
Sbjct: 3 AEPIRFDGRVVLVTGAGNGLGRQYALAFAERGASVVVNDLGGDTKGEGKSGRAADKVVQE 62
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR +GGKAVA+Y+SVE+G++VV+TA+ AFGRIDVVVNNAGILRD+S R+S+ DWD++ R
Sbjct: 63 IRAKGGKAVADYNSVEQGDQVVETAIKAFGRIDVVVNNAGILRDKSILRMSELDWDLVQR 122
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHL+GSF VTRAAW HMKKQK+GRIIMT+S SGIYGNFGQANYSAAKLGL+GL+N+LA E
Sbjct: 123 VHLKGSFLVTRAAWPHMKKQKFGRIIMTTSTSGIYGNFGQANYSAAKLGLVGLSNTLAQE 182
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K NI CN IAP AGSR+T+TVM ++++EALKPEY+APLVL+LCHESCEEN GLFE
Sbjct: 183 GAKYNIKCNAIAPVAGSRLTKTVMSDEMIEALKPEYIAPLVLYLCHESCEENAGLFETAV 242
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
GW + RW+RT G ++R++ +TPE V+ NW+ I D+ +A P + +V K
Sbjct: 243 GWFSQTRWQRTKGKLLRKEVEFVTPEMVRDNWEGITDWTDAENPTEASNVLQFVEDV--K 300
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIK-DPKD 360
+ +A + S S + QK+P +YT + I+YALGVG S + D
Sbjct: 301 EARQEQENARNASPGKS---------MTQKMPDAKKSYTHNDVILYALGVGVSFQEDYSH 351
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YE DF+ LPTFG+I+GQ SMMG E+ G+ + AK+LHGEQYLE+YKPLP +
Sbjct: 352 LKFLYENHEDFAALPTFGIILGQGSMMGIAGGEMAGIKFDPAKLLHGEQYLEVYKPLPTS 411
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGKRTSDKVK 479
G + A V DVLDKG G +++++V + E +E IC NQFS++L G+GGFGGKR+SDKVK
Sbjct: 412 GSITNRAEVVDVLDKGKGALVLLNVTTLDEQEEPICFNQFSIYLGGAGGFGGKRSSDKVK 471
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
V+ P+R PDA + + T L QAALYRLSGD+NPLH+DP FA + G KPILHGLC+ G+
Sbjct: 472 PVVSPPSRTPDASVKEKTGLTQAALYRLSGDYNPLHVDPAFAQMGGLSKPILHGLCSLGY 531
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VL+Q+A+NDVS+FKA+K RF+KPV PGQT+QT+MWKEG+R+HFQ+KV E G +VIS
Sbjct: 532 SARHVLKQYANNDVSKFKALKVRFSKPVVPGQTIQTDMWKEGSRVHFQSKVVENGTVVIS 591
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
AYVD T T PS G L+S +F E+ +R+ D P++VKKV +F WH+ KGG
Sbjct: 592 GAYVDF--TELTPNIPPSSSG-LKSEALFAELKKRVSD-HPDLVKKVKGIFLWHVKKGGK 647
Query: 660 IGAKWTIDLKSGSGKVYQGPAK-GAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARG 718
+ + WT+DLK+ G V+ GP K G DTTI DED + + GK +PQ+ F G+LK G
Sbjct: 648 VVSSWTVDLKTPGGAVFTGPPKGGKPDTTITCEDEDLISMATGKANPQQLFMKGKLKVAG 707
Query: 719 NIMLSQKLQMILKDYAKL 736
NIML+ KL + KDYAK+
Sbjct: 708 NIMLTMKLNQLFKDYAKI 725
>ref|XP_001088200.1| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 isoform 3
[Macaca mulatta]
Length = 597
Score = 1038 bits (2684), Expect = 0.0, Method: Composition-based stats.
Identities = 581/599 (96%), Positives = 588/599 (98%), Gaps = 2/599 (0%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG
Sbjct: 1 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 60
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV
Sbjct: 61 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 120
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 317
RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSE GVSANHTS AT
Sbjct: 121 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSE-GVSANHTSHAT 179
Query: 318 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKF+YEGSSDFSCLPTF
Sbjct: 180 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFVYEGSSDFSCLPTF 239
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVIIGQKS+MGGGLAEIPGLSINFAKV+ GE ++ KPL R GKLKCEAVVADVLDKGS
Sbjct: 240 GVIIGQKSLMGGGLAEIPGLSINFAKVI-GEPSMKAEKPLKRVGKLKCEAVVADVLDKGS 298
Query: 438 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 497
GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT
Sbjct: 299 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 358
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARR+LQQFADNDVSRFK
Sbjct: 359 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRILQQFADNDVSRFK 418
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTS TSAKTPS
Sbjct: 419 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSDTSAKTPS 478
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGGKLQST VFEEIGRRLKD+GPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ
Sbjct: 479 EGGKLQSTLVFEEIGRRLKDVGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 538
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 539 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 597
>ref|XP_859266.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 3 [Canis familiaris]
Length = 599
Score = 1018 bits (2634), Expect = 0.0, Method: Composition-based stats.
Identities = 520/599 (86%), Positives = 555/599 (92%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LAIEG+ SNIHCNTIAP AG
Sbjct: 1 MKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLAIEGKTSNIHCNTIAPTAG 60
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEVG GWIGKLRWERTLGAIV
Sbjct: 61 SRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEVGGGWIGKLRWERTLGAIV 120
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 317
RQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V++ IDS+GGVS NHTS A
Sbjct: 121 RQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVVNTIDSDGGVSTNHTSHAA 180
Query: 318 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
STATS FAGAIG K PPFS AYTELE IMYALGVGAS+K+PKD+KFIYEGS+DFSCLPTF
Sbjct: 181 STATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPKDMKFIYEGSTDFSCLPTF 240
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPRAG L+CEAVVADVLDKGS
Sbjct: 241 GVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPRAGNLRCEAVVADVLDKGS 300
Query: 438 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 497
G VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDKVK VA+PNRPPDAVLTDTT
Sbjct: 301 GSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVKATVAVPNRPPDAVLTDTT 360
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGFSAR VLQ+FADNDVSRFK
Sbjct: 361 SLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGFSARHVLQKFADNDVSRFK 420
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVISNAYVDL PTS TSA+TPS
Sbjct: 421 AIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVISNAYVDLMPTSDTSAQTPS 480
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGNI AKWTIDLKSG GKVYQ
Sbjct: 481 EGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGNIAAKWTIDLKSGFGKVYQ 540
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 541 GPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 599
>ref|XP_001606624.1| PREDICTED: similar to estradiol 17 beta-dehydrogenase [Nasonia
vitripennis]
Length = 722
Score = 1000 bits (2587), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 493/736 (66%), Gaps = 30/736 (4%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
LRFDGRVV+VTGAGAGLGRAYAL F RGA VVVNDLGG G G + AD VV+E
Sbjct: 3 TDNLRFDGRVVIVTGAGAGLGRAYALLFGSRGASVVVNDLGGGRHGDGSSTKIADTVVDE 62
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR+ GGKAVANY++V +G+K+V+TA+DAFGRID+V+NNAGILRD+SF R+SD DWD+IH
Sbjct: 63 IRKLGGKAVANYNNVLDGDKIVQTAIDAFGRIDIVINNAGILRDKSFVRMSDTDWDLIHD 122
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VH++GS + TRAAW + +KQ +GR+I+TSS SG+YGNFGQANYSAAKLGL+GLAN+LAIE
Sbjct: 123 VHVKGSMKTTRAAWPYFRKQNFGRVILTSSNSGLYGNFGQANYSAAKLGLVGLANTLAIE 182
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K+NIH N I P A SR+T+ ++P + E LKPEY+AP+V WLCH+ C+ENG + E
Sbjct: 183 GVKNNIHTNVIVPTAASRLTEDILPPEFFEQLKPEYIAPVVAWLCHDDCKENGSIIESAI 242
Query: 242 GWIGKLRWERTLGAIV-RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
GW GK R R+ G ++ R N +TPEAV+ NW + D NA SIQE TG I+ L
Sbjct: 243 GWAGKCRIVRSNGHLLRRDMNDIVTPEAVRDNWNTVTDMTNAKAYDSIQEVTGEIMGSLE 302
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+ S S+ T+ YT +AI+YALGVGA+ ++ +D
Sbjct: 303 KLKSGNSSSSQEFVMQTN--------------------YTHRDAILYALGVGATRQELRD 342
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI--PGLSINFAKVLHGEQYLELYKPLP 418
+ ++YE +FS +P+F V G +M L + P + ++ ++LHGEQYLE++K LP
Sbjct: 343 ICYLYENHENFSLIPSFYVTFGPMGLMTTTLVQDALPNVQLDPTRILHGEQYLEIHKKLP 402
Query: 419 RAGKLKCEAVVADVLDKGSGVVIIM--DVYSYSEKELICHNQFSLFLVGSGGFGGKRTSD 476
GK++ + DVLDKG G V+++ + Y + + + NQ S F VG+GGFGG R S
Sbjct: 403 VEGKVESRFRIQDVLDKGKGAVVLVQYETYDVATGDKLTTNQISAFAVGAGGFGGPRNSR 462
Query: 477 KVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCT 536
+ V P R P +T TS +QAA+YRLSGD+NPLH+D N A++AGF +PILHGLC+
Sbjct: 463 HLVPCVEPPKRKPCVSVTQKTSPDQAAIYRLSGDYNPLHMDDNIATMAGFSEPILHGLCS 522
Query: 537 FGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDI 596
GFS R VLQ FAD D K +K RFAKPV PGQTL+T+MW+ GNRIHFQT V E
Sbjct: 523 LGFSTRHVLQTFADGDPDALKTLKVRFAKPVLPGQTLRTDMWRNGNRIHFQTTVVENNSN 582
Query: 597 VISNAYVDLAP--TSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHI 654
VI+ AY+DL T + S L+S VF ++ +K PE VKK+N VF + +
Sbjct: 583 VITGAYMDLKEVKTPSIMSNLCSAAKNLESDAVFAQMADYVKS-HPEQVKKINGVFHYIV 641
Query: 655 TKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRL 714
T G A WT+DLK VY+G +G DTT+ + D+D +++ LGKL+PQ AF G+L
Sbjct: 642 TSKGEPQADWTLDLK--KCVVYKGKPEGKVDTTLTIDDKDMIQLALGKLNPQMAFMKGKL 699
Query: 715 KARGNIMLSQKLQMIL 730
K +GNIML+QKL+ ++
Sbjct: 700 KIKGNIMLTQKLKSLI 715
>emb|CAG09600.1| unnamed protein product [Tetraodon nigroviridis]
Length = 716
Score = 997 bits (2578), Expect = 0.0, Method: Composition-based stats.
Identities = 446/670 (66%), Positives = 540/670 (80%), Gaps = 1/670 (0%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
L F+GRVVLVTGAG GLGR YALAFA+RGA VVVNDLGG+ KG GK S AADKVVEEIR
Sbjct: 3 LSFEGRVVLVTGAGGGLGREYALAFAQRGASVVVNDLGGNTKGGGKSSAAADKVVEEIRA 62
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
+GGKAVA+YDSVE+GEK++++AL+ FGRIDVVVNNAGILRDRSF R SD DWD+IHR+HL
Sbjct: 63 KGGKAVASYDSVEDGEKLIQSALERFGRIDVVVNNAGILRDRSFPRTSDVDWDLIHRIHL 122
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
RGSF VTRAAW+ MKKQK+GRIIMT+SA+GIYGNFGQ+NYS+AKLGLLGLAN+LAIEGRK
Sbjct: 123 RGSFLVTRAAWDQMKKQKFGRIIMTASAAGIYGNFGQSNYSSAKLGLLGLANTLAIEGRK 182
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
NIHCNT+AP AGSR+T+TVMP DLV +LKPEYVAPLVLWLCHE C+ENGGLFEVGAGW+
Sbjct: 183 YNIHCNTVAPVAGSRLTETVMPPDLVASLKPEYVAPLVLWLCHEQCQENGGLFEVGAGWV 242
Query: 245 GKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDS 304
GKLRWER+ G IVRQKN MTPEAV+ W +ICDF +A+KP S+QES + + VLS++D+
Sbjct: 243 GKLRWERSRGQIVRQKNRAMTPEAVRDGWDRICDFTDATKPSSVQESLQAFVSVLSQVDA 302
Query: 305 EGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFI 364
G V A+ + A + + + AIGQ LP ++ + + I+YALGVG S KDP L+F+
Sbjct: 303 GGQVEASPAAAAAAPSGINPSVAIGQILPRSTFTFNHTQCILYALGVGMSTKDPDHLRFL 362
Query: 365 YEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLK 424
YEG DFSCL FGVI Q + M G L +PGL+I+ ++LHGEQYLELY+PLP +G L
Sbjct: 363 YEGHPDFSCLSHFGVIPPQAAFMEG-LTSVPGLTIDLTQMLHGEQYLELYRPLPTSGTLT 421
Query: 425 CEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAI 484
EA +ADVLDKGSG V+++DV +YS +ELIC+NQFSLF+VG+GGFGGKRTS K K ++
Sbjct: 422 SEATIADVLDKGSGAVVLLDVNTYSGEELICYNQFSLFVVGAGGFGGKRTSAKSKASLPA 481
Query: 485 PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRV 544
P R PD V+TD T+ +QAALYRLSGDWNPLHIDP+FA++ GF PILHGLC+FGF+AR V
Sbjct: 482 PKRAPDVVMTDCTTRDQAALYRLSGDWNPLHIDPSFAAIGGFKAPILHGLCSFGFAARHV 541
Query: 545 LQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVD 604
L+QFA+N+ SRFKAIK RF KPV PGQ+LQT MWKEG+RIH + V+ET D+V+S AYVD
Sbjct: 542 LKQFANNEPSRFKAIKVRFVKPVMPGQSLQTAMWKEGSRIHIECTVKETNDVVLSGAYVD 601
Query: 605 LAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKW 664
L + S + P++GG LQS VF EIGRR+K+ G E+VKKVNAVF W ITK G A W
Sbjct: 602 LHQAAEASPEPPAQGGALQSDLVFAEIGRRIKEAGSELVKKVNAVFSWEITKEGRTAAHW 661
Query: 665 TIDLKSGSGK 674
+ L G+
Sbjct: 662 SFLLGQAEGQ 671
>ref|XP_001652466.1| estradiol 17 beta-dehydrogenase [Aedes aegypti]
gb|EAT41321.1| estradiol 17 beta-dehydrogenase [Aedes aegypti]
Length = 719
Score = 988 bits (2556), Expect = 0.0, Method: Composition-based stats.
Identities = 383/740 (51%), Positives = 500/740 (67%), Gaps = 33/740 (4%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
LR+DGRVV+VTGAGAGLGR YAL F RGA VVVNDLGG+F G GK + AADKVVEEI
Sbjct: 7 DQLRYDGRVVVVTGAGAGLGREYALLFGSRGAKVVVNDLGGNFHGQGKSN-AADKVVEEI 65
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R GG AVA+Y+SV +GEK+++TA++AFGR+DV++NNAGILRDRS ARISDEDW++IH V
Sbjct: 66 RSAGGTAVADYNSVVDGEKIIQTAMEAFGRVDVLINNAGILRDRSLARISDEDWNLIHDV 125
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
H++GSF TRAAW MKKQ +GRIIMTSS SG+YGNFGQANYSAAKLGL+GLAN++AIEG
Sbjct: 126 HMKGSFMTTRAAWPIMKKQNFGRIIMTSSNSGVYGNFGQANYSAAKLGLVGLANTVAIEG 185
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 242
+K+NIHCN I P A SRMT+ ++PE L LKP+ +AP+V +LCHESCE+NG + E AG
Sbjct: 186 QKNNIHCNVIVPTAASRMTEGILPEILFNELKPKLIAPVVAYLCHESCEDNGAIIESAAG 245
Query: 243 WIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
W K+ + R G+++R + +TPE V+ W K+ D A +I E++ S++EVL K
Sbjct: 246 WATKVHFVRGKGSVLRTSIDEDVTPEYVRNVWDKVTDMSEAKHLNAIGEASLSLVEVLEK 305
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDL 361
+ EG + N + +Y + + I+YALGVGA++ D DL
Sbjct: 306 L-REGKSAENSVTE--------------------TYKFNYKDVILYALGVGATVTDESDL 344
Query: 362 KFIYEGSSDFSCLPTFGVIIGQKSMMGGGLA--EIPGLSINFAKVLHGEQYLELYKPLPR 419
+F+YE +FS LPTF ++ G S+MG L IP + +LHGEQY+EL+ +P
Sbjct: 345 RFLYENHPEFSVLPTFFILPGLLSVMGSDLTAKAIPHAQFDLTNILHGEQYIELFDSVPT 404
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGK-RTSDK 477
G L + V DVLDK SG +++ S+ E L+ Q S F+VG G F GK + S +
Sbjct: 405 DGVLTTTSTVIDVLDKKSGALVVTQSESFDENGTLVARGQSSTFVVGVGNFNGKSKASSE 464
Query: 478 VKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTF 537
VK + P R PDA + TS +QAALYRLSGD NP+HIDP+F+++AG+ PILHGLCT
Sbjct: 465 VKALMPNPKRSPDASVQIKTSRDQAALYRLSGDLNPMHIDPSFSAIAGYKTPILHGLCTM 524
Query: 538 GFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKE-GNRIHFQTKVQETGDI 596
G S + VL+++ ++D S FKA K RF+KPV PGQTL+ +MWKE NR+ F+T V ET
Sbjct: 525 GISVKAVLKRYGNDDSSLFKAAKVRFSKPVLPGQTLRIDMWKEANNRVCFRTVVVETNTE 584
Query: 597 VISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITK 656
V+S AYVDL T G LQS VF I R+ + K +NAVF + IT
Sbjct: 585 VLSGAYVDLKKIVLKPNMTA--GKSLQSDAVFAGIKDRVSE-NEAKAKAINAVFLYKITD 641
Query: 657 GGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKA 716
GG + +W +DLK+ KVY+GP +G ADTT+ +SD D +++ LGKL PQ AF G+LK
Sbjct: 642 GGKVSKEWVLDLKNA--KVYEGPVQGKADTTMTISDSDMVDLALGKLQPQAAFMKGKLKI 699
Query: 717 RGNIMLSQKLQMILKDYAKL 736
GNIML+QKL +LK AKL
Sbjct: 700 TGNIMLAQKLAPLLKTEAKL 719
>ref|XP_393475.2| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
[Apis mellifera]
Length = 704
Score = 983 bits (2542), Expect = 0.0, Method: Composition-based stats.
Identities = 356/737 (48%), Positives = 474/737 (64%), Gaps = 45/737 (6%)
Query: 1 MGSP-LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVV 59
MG L F RVV++TGAGAGLGR YAL FA RGA VVVNDLGG G G + AD VV
Sbjct: 1 MGEEKLSFVNRVVIITGAGAGLGRTYALLFASRGASVVVNDLGGSRDGDGSSTKIADSVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EIR+ GG+AVANYDSV +GEK+VKTA+DAFGRID++VNNAGILRD+SFA++ + DWD+I
Sbjct: 61 NEIRKNGGRAVANYDSVLDGEKIVKTAIDAFGRIDILVNNAGILRDKSFAKMLESDWDLI 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
VHL+G+F+ T+AAW + KQKYGRIIMT+S SG+YGNFGQANYSAAK+GL+GL N+LA
Sbjct: 121 QNVHLKGAFKTTQAAWPYFVKQKYGRIIMTASNSGLYGNFGQANYSAAKMGLIGLTNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG++ NIH N I P A SR+T+ ++P D + LKPE +AP+V+WLCHE C ENG + E
Sbjct: 181 IEGKQKNIHTNVIIPTAASRLTEDILPPDFFKELKPELIAPVVVWLCHEKCMENGSIIES 240
Query: 240 GAGWIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEV 298
GW GK R+ G+ +RQ + +TPE V+ W+ I D NA SI+E TG +
Sbjct: 241 ALGWAGKCHVIRSSGSTLRQDLSSEITPEDVENKWQVITDMSNAKHFNSIEEVTGEFMTT 300
Query: 299 LSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDP 358
+ SE + + + Y + I+YALGVGAS++ P
Sbjct: 301 IETTKSENSQPSESQNSGV-----------------LRHTYNYRDIILYALGVGASVQIP 343
Query: 359 KDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAE--IPGLSINFAKVLHGEQYLELYKP 416
D +++YE S+F+ LPTF V+ + + E +P + ++ K+LHGEQY+E+YK
Sbjct: 344 TDFRYLYENDSNFAVLPTFYVVYAPMVALEFSMYEKFLPHIELDPTKILHGEQYIEVYKQ 403
Query: 417 LPRAGKLKCEAVVADVLDKGSGVVII--MDVYSYSEKELICHNQFSLFLVGSGGFGGKRT 474
LP ++ + DV+DKG G +++ D + S ++ + Q +F++G+G F GKRT
Sbjct: 404 LPTEATVETRYKIVDVVDKGKGALVVIQHDTFDTSNEDKLSTGQMIIFVIGAGNFKGKRT 463
Query: 475 SDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGL 534
S + + PNR PD +T TS +QAALYRLSGD NPLHID N + +AGF +PILHGL
Sbjct: 464 SSYIIPTIESPNREPDTSVTQQTSQDQAALYRLSGDQNPLHIDSNMSMIAGFKRPILHGL 523
Query: 535 CTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETG 594
CT GFS R +LQ + D S FKAIK RFAKPV PGQTL+T+MW+EGNRIHFQT E
Sbjct: 524 CTLGFSVRHILQTYTGGDPSLFKAIKTRFAKPVIPGQTLRTDMWQEGNRIHFQTHTVEEN 583
Query: 595 DIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHI 654
+V+ N L+S VF +I +K E VKK+N VF +HI
Sbjct: 584 ILVVINT-------------------SLESDAVFFKIAEYVKTNSDE-VKKINGVFLYHI 623
Query: 655 TKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRL 714
G + A+WT+DLK +VY+G K D T+ L D D +++ LGKL+PQ AF +L
Sbjct: 624 LVNGKLKAQWTLDLK--KSEVYRGEPKSKPDATLTLEDADMIQMALGKLNPQVAFVRQKL 681
Query: 715 KARGNIMLSQKLQMILK 731
K GNIML+QKL+ +++
Sbjct: 682 KITGNIMLTQKLKTLIE 698
>ref|XP_001843060.1| peroxisomal multifunctional enzyme type 2 [Culex pipiens
quinquefasciatus]
gb|EDS30335.1| peroxisomal multifunctional enzyme type 2 [Culex pipiens
quinquefasciatus]
Length = 719
Score = 979 bits (2531), Expect = 0.0, Method: Composition-based stats.
Identities = 386/740 (52%), Positives = 498/740 (67%), Gaps = 33/740 (4%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
S LR+DGRVV+VTGAGAGLGR YAL F RGA VVVNDLGG+F G GK + AADKVVEEI
Sbjct: 7 SQLRYDGRVVVVTGAGAGLGREYALLFGSRGAKVVVNDLGGNFHGQGKSN-AADKVVEEI 65
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R RGG AVA+Y+SV +G+K+++TA++AFGR+DV+VNNAGILRD+S ARISDEDW++IH V
Sbjct: 66 RERGGTAVADYNSVVDGDKIIQTAMEAFGRVDVLVNNAGILRDKSIARISDEDWNLIHDV 125
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
HL+GSF TRAAW MKKQ YGRIIMTSS SG+YGNFGQANYSAAKLGL+GLAN++AIEG
Sbjct: 126 HLKGSFVTTRAAWPIMKKQNYGRIIMTSSNSGVYGNFGQANYSAAKLGLVGLANTVAIEG 185
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 242
K++IHCN I P A SRMT+ ++PE L LKP+ +AP+V +LCHESCE+ G + E AG
Sbjct: 186 AKNDIHCNVIVPTAASRMTEGILPEILFNELKPKLIAPVVAFLCHESCEDTGAIIESAAG 245
Query: 243 WIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
W K+ + R G+++R + +TPE VK W K+ D A +I E++ ++++VL K
Sbjct: 246 WATKVHFVRGKGSVLRTSLDESVTPEYVKGVWSKVTDMSEAKHLNAIGEASLTLVDVLEK 305
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDL 361
+ GV A ++ T Y + + I+YALGVGA++ D DL
Sbjct: 306 L--REGVPAGNSVTET-------------------YKFNYKDVILYALGVGATVTDENDL 344
Query: 362 KFIYEGSSDFSCLPTFGVIIGQKSMMGGGLA--EIPGLSINFAKVLHGEQYLELYKPLPR 419
+F+YE SDFS LPTF ++ G S+MG L I S + +LHGEQY+EL+ +P
Sbjct: 345 RFLYENHSDFSTLPTFFILPGLLSVMGSNLTASAITHASFDLTNILHGEQYIELFDNVPT 404
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGK-RTSDK 477
G L + V DVLDK SG ++I SY E L+ Q S F+VG G F GK + SD
Sbjct: 405 EGVLTTTSTVIDVLDKKSGALVITQSDSYDENGTLVARGQSSTFIVGVGNFNGKSKASDA 464
Query: 478 VKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTF 537
VK V P R PDA + T+ +QAALYRLSGD NP+HIDP+F+++AG+ PILHGLCT
Sbjct: 465 VKPLVPNPKRAPDASVQVKTTKDQAALYRLSGDLNPMHIDPSFSAIAGYKTPILHGLCTM 524
Query: 538 GFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKE-GNRIHFQTKVQETGDI 596
G S + VL+QF +D + FKA K RF+KPV PGQTL+ +MW+E NR+ F+T V ET
Sbjct: 525 GVSVKAVLKQFGGDDSALFKAAKVRFSKPVLPGQTLRVDMWREANNRVCFRTVVVETNTE 584
Query: 597 VISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITK 656
V+S AYVD T G LQS VF I R+ + K +NAV+ + IT
Sbjct: 585 VLSGAYVDFKQIVVKPNMT--SGKSLQSDAVFAGIKERIAE-NEAKAKSINAVYLYKITD 641
Query: 657 GGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKA 716
G + +W +D K +GKVY+GP +G ADTT+ +SD D +++ LGKL PQ AF G+LK
Sbjct: 642 SGKVAKEWVLDCK--AGKVYEGPVQGKADTTMTISDADMVDLALGKLQPQTAFMKGKLKI 699
Query: 717 RGNIMLSQKLQMILKDYAKL 736
GNIML+QKL +LK AKL
Sbjct: 700 TGNIMLAQKLAPLLKTEAKL 719
>ref|XP_974784.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
[Tribolium castaneum]
Length = 715
Score = 978 bits (2529), Expect = 0.0, Method: Composition-based stats.
Identities = 390/741 (52%), Positives = 500/741 (67%), Gaps = 31/741 (4%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MG LRFDGRVV+VTGAGAGLGRAYAL F RGA VVVNDLGG G GK S AAD VVE
Sbjct: 1 MG-DLRFDGRVVVVTGAGAGLGRAYALLFGSRGAKVVVNDLGGGRHGDGKSSSAADAVVE 59
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EI+R GG AVA+Y+SV +GEKV+KTALD FGR+DV++NNAGILRD+SFARISD+DWD++H
Sbjct: 60 EIKRNGGTAVADYNSVVDGEKVIKTALDNFGRVDVLINNAGILRDKSFARISDQDWDLVH 119
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
VHL+GSF+ T+AA+ KKQ YGRIIMTSS SG+YGNFGQANYSAAK+GL+GLA+++AI
Sbjct: 120 AVHLKGSFKTTQAAFPIFKKQGYGRIIMTSSNSGLYGNFGQANYSAAKMGLVGLASTIAI 179
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG K+NIHCN I P A SR+T+ ++P DL LKPE +AP+V +LCHESC ENG + E
Sbjct: 180 EGAKNNIHCNVIVPTAASRLTEDILPPDLYAELKPELIAPVVAYLCHESCTENGSIIESA 239
Query: 241 AGWIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
AGW GK + R+ G+++R K ++ E V+ W+K+ NA SIQE+TG+++ L
Sbjct: 240 AGWAGKCQIIRSNGSLLRTKITDGVSVENVRDKWQKVTSMSNAEHLDSIQEATGALMTSL 299
Query: 300 SKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+ S G V Y +T+ + I+YALGVGAS+K+P
Sbjct: 300 DSLRS-GEVKDEEVD---------------------VYNFTQKDIILYALGVGASLKNPN 337
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAE--IPGLSINFAKVLHGEQYLELYKPL 417
+LKFIYE DFS LPTF ++ ++M E IPG +++ A++LHGEQY+E +
Sbjct: 338 ELKFIYENDEDFSALPTFYIMPAMQAMFTSSKLESAIPGKTVSLAQILHGEQYIEFLGEV 397
Query: 418 PRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGKRTSD 476
P+ GKL + + +VLDKGSG I+ ++ ++ E L+ NQ F+VG+G FGG RT
Sbjct: 398 PKEGKLFSKNSIVEVLDKGSGAAIVQNIETFDEQGNLLIRNQTVAFVVGAGNFGGSRTGT 457
Query: 477 KVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCT 536
K + P R PD LTD T+++QAALYRLSGD NPLHIDPN A +AGF +PILHGLCT
Sbjct: 458 KAIPCQSKPPRVPDLSLTDKTTIDQAALYRLSGDTNPLHIDPNMAVVAGFKQPILHGLCT 517
Query: 537 FGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDI 596
GFS R +++ +A D S KA KARF KPV PGQTL+ + W+EG+RIHF+T V ET +
Sbjct: 518 LGFSIRLLVRAYAGGDPSFVKACKARFMKPVIPGQTLRVDFWREGSRIHFETSVVETNTV 577
Query: 597 VISNAYVDLAPTSGTSAKTPS-EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHIT 655
VI AYVDL S L+S VF+ I ++K P K + VF + IT
Sbjct: 578 VIGGAYVDLNSVKVMEPINNSVSAPALESDAVFQFIIDQVK-ADPNKAKSIGGVFLYKIT 636
Query: 656 KGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLK 715
K G +WT+DLK+ KVY+G +G TT+ ++DEDFM + GKL PQ AF G+LK
Sbjct: 637 KNGKEAKQWTMDLKNA--KVYEGAPEGKPSTTLTIADEDFMLLAQGKLQPQAAFMKGKLK 694
Query: 716 ARGNIMLSQKLQMILKDYAKL 736
GNIML+QKL ILK AKL
Sbjct: 695 ITGNIMLAQKLAPILKANAKL 715
>emb|CAB55552.1| Fox2 protein [Glomus mosseae]
Length = 1015
Score = 973 bits (2517), Expect = 0.0, Method: Composition-based stats.
Identities = 377/758 (49%), Positives = 505/758 (66%), Gaps = 32/758 (4%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
L+FDG+V +VTGAG GLGRAYAL + GA VVVNDLG G G S AADKVVEE
Sbjct: 267 SEDLKFDGKVAIVTGAGGGLGRAYALLLGKLGASVVVNDLGVSAHGQGATSSAADKVVEE 326
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR+ GGKAVANYDSVE+GEK+V+TA+ AFGR+D+++NNAGILRD+SFAR++D+DWD++ R
Sbjct: 327 IRQAGGKAVANYDSVEDGEKIVETAIKAFGRVDIIINNAGILRDKSFARMTDQDWDLVQR 386
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHLRG+++VT+AAW ++ KQKYGRII T+S+ G+YGNFGQANYS AKLG+LG +N+LA+E
Sbjct: 387 VHLRGTYKVTKAAWPYLTKQKYGRIINTASSVGLYGNFGQANYSTAKLGILGFSNTLALE 446
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
GRK+NI NTIAPNAG+RMT T+ P D+VEA KP+YVAP V +L HE+C G +FEVG
Sbjct: 447 GRKNNIFVNTIAPNAGTRMTATIWPPDMVEAFKPDYVAPFVSFLAHEACPSTGNVFEVGG 506
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN--ASKPQSIQESTGSIIEVL 299
GW+ ++RW+R G +TPE + + I +F++ A+ P + Q++ E
Sbjct: 507 GWVAQVRWQRAGGIGFPTS-KALTPEDIASKIDIITNFDDGRATHPTTTQQALQQFFENF 565
Query: 300 SKID-SEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDP 358
+ SE G S + ++ + + A +K P + Y E + ++YALG+GA+
Sbjct: 566 ANAQKSESGQSKSKSNNSKIDVEA----AKKRKFEPHVFEYKERDVMLYALGIGAT---R 618
Query: 359 KDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLP 418
KDL+++YE S +FS +PTFGVI L+E+ G N +LHGEQYLEL KP+P
Sbjct: 619 KDLQWVYENSDNFSVIPTFGVIPAIILSNTLPLSEVLG-DFNVMMLLHGEQYLELKKPIP 677
Query: 419 RAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEK-ELICHNQFSLFLVGSGGFGGKRTSDK 477
+GKL V D+LDKG GV I + + EK E+I NQ +LF+ G GGFGGK+T D
Sbjct: 678 TSGKLISTPYVIDILDKGKGVSFIFGITTTDEKGEVIFENQTTLFIRGIGGFGGKKTGDD 737
Query: 478 VKVAVA---IPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGL 534
A A P R PD V+ + T+ NQAALYRLSGD+NPLHIDP+ +++ GFD PILHG+
Sbjct: 738 RGAATASNIPPKRAPDVVVKEKTNENQAALYRLSGDYNPLHIDPSMSAMGGFDVPILHGM 797
Query: 535 CTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETG 594
CTFG S + + F ND + FK+IKAR A PV+PG+TL+T+MWK+G+++ FQT+V E
Sbjct: 798 CTFGISGKHIFSTFGKNDPNTFKSIKARLAAPVFPGETLETQMWKDGDKVIFQTRVVERD 857
Query: 595 DIVISNAYVDLAPTS------GTSAKTPSEGGKL---QSTFVFEEIGRRLKDIGP----E 641
I I++A V+L +S G + TPS G + QS+ VFE++ L P
Sbjct: 858 VICIASAAVELRGSSASGASMGAPSATPSAGISVPGFQSSSVFEQLKAGLDAASPAERQA 917
Query: 642 VVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLG 701
VKKV F+ +I W ID K+G G V GP+ AD TI +SD DFME+ G
Sbjct: 918 QVKKVKGSFQLNIKNAEGKEQSWYIDFKTGDGAVGIGPSPKKADATIGVSDADFMELASG 977
Query: 702 KLDPQKAFFSGRLKARGNIMLSQKLQMIL---KDYAKL 736
KL+ QKAF SG+LK +GN+ML+ KL +L K +KL
Sbjct: 978 KLNAQKAFMSGKLKIKGNMMLATKLGDVLAGGKSKSKL 1015
Score = 362 bits (930), Expect = 6e-98, Method: Composition-based stats.
Identities = 156/332 (46%), Positives = 212/332 (63%), Gaps = 46/332 (13%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M LRFDGR V+VTGAG V+
Sbjct: 1 MAQELRFDGRTVIVTGAGG---------------------------------------VD 21
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EI + GGKAV+NY+SVE+G+K+V+TA+ AFGR+D+++NNAGILRD+SFARI+D DWD+I
Sbjct: 22 EIIKAGGKAVSNYNSVEDGDKIVETAMKAFGRVDILINNAGILRDKSFARITDSDWDLIQ 81
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
VH+RGS++VT+AAW+ +KQK+GRII T+SA+GIYGNFGQANY+ KL L+ +LA
Sbjct: 82 AVHVRGSYKVTKAAWDIFRKQKFGRIINTASAAGIYGNFGQANYT--KLALVSFTETLAK 139
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG K+NIH N IAP A SRMT++VMP D++ ALKP+YVAPLV++LCHES +ENG LFEVG
Sbjct: 140 EGAKANIHANVIAPIAASRMTESVMPPDVLAALKPDYVAPLVMYLCHESTQENGSLFEVG 199
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AG++ KLRWER+ GA+ + + P V W +I +F N + P S ++ + +L
Sbjct: 200 AGFVAKLRWERSKGAVFK-ADDTFLPGTVAVKWNEITEFTNPTYPTSPGDA--DFVGLLE 256
Query: 301 KIDS--EGGVSANHTSRATSTATSGFAGAIGQ 330
K + S + +G G +G+
Sbjct: 257 KAKALPSNPKSEDLKFDGKVAIVTGAGGGLGR 288
>ref|XP_314766.4| AGAP008667-PA [Anopheles gambiae str. PEST]
gb|EAA10131.4| AGAP008667-PA [Anopheles gambiae str. PEST]
Length = 724
Score = 970 bits (2509), Expect = 0.0, Method: Composition-based stats.
Identities = 383/743 (51%), Positives = 494/743 (66%), Gaps = 35/743 (4%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
LR+DGRVV+VTGAGAGLGR YAL FA RGA VVVNDLGG+F G GK + AADKVVEE
Sbjct: 9 SKQLRYDGRVVVVTGAGAGLGREYALLFASRGAKVVVNDLGGNFHGQGKSN-AADKVVEE 67
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR GG AV +Y+SV EG+K+V+TAL+ FGRIDV+VNNAGILRDRS ARISDEDW++IH
Sbjct: 68 IRAAGGVAVPDYNSVVEGDKIVQTALENFGRIDVLVNNAGILRDRSLARISDEDWNLIHD 127
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHL+GSF TRAAW MKKQ YGRIIMTSS SG+YGNFGQANYSAAKLGL+GLAN++AIE
Sbjct: 128 VHLKGSFLTTRAAWPVMKKQNYGRIIMTSSNSGVYGNFGQANYSAAKLGLVGLANTVAIE 187
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K+NI CN I P A SRMT+ ++PE L LKP+ +AP+V +LCHESCE+ G + E A
Sbjct: 188 GAKNNIQCNVIVPTAASRMTEGILPEILFNELKPKLIAPVVAYLCHESCEDTGAIIESAA 247
Query: 242 GWIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
GW K+ + R G ++R + ++PE V+ W ++ D A + +I E++ S++ VL
Sbjct: 248 GWATKVHFVRGRGCVLRTSIDEDVSPEYVQQVWNRVTDMSEAKRLNAIGEASLSLVGVLE 307
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+ N+ + T T GF +AI+YALGVGAS+ DP D
Sbjct: 308 KLRD----GQNNENSVTETFRYGF-----------------KDAILYALGVGASVTDPTD 346
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLA--EIPGLSINFAKVLHGEQYLELYKPLP 418
LKF+YE + +F+ LPTF ++ G ++MG L I + + +LHGEQY+EL++
Sbjct: 347 LKFLYENNPEFAVLPTFFILPGLLAVMGSSLTASAIKHTTFDLTNILHGEQYIELFEAPA 406
Query: 419 RAGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGK-RTSD 476
G L + V DV+DK SG ++I SY E L+ NQ S F+VG+G F GK +
Sbjct: 407 TEGVLTTTSTVLDVVDKKSGALVITQSDSYDEQGTLVARNQSSTFVVGAGNFNGKTKAGP 466
Query: 477 KVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCT 536
+VK V P R PDA + T NQAA+YRLSGD NP+HIDP+F+++AG+ PILHGLCT
Sbjct: 467 EVKPLVPNPKRSPDASVEVPTHQNQAAVYRLSGDLNPMHIDPSFSAIAGYKVPILHGLCT 526
Query: 537 FGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKE-GNRIHFQTKVQETGD 595
G S + VL+QF +D + F+A K RF+KPV PGQTL+ +MWKE NR+ F+T V ET
Sbjct: 527 MGVSVKAVLKQFGGDDPTLFRAAKVRFSKPVLPGQTLRVDMWKEPNNRVCFRTVVVETST 586
Query: 596 IVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHIT 655
V+S AYVD T + LQS VF I R+ + K +NAVF + IT
Sbjct: 587 EVLSGAYVDFKQIVIKPNMTAAV--DLQSDAVFAGIKDRVAE-NEAKAKAINAVFLYKIT 643
Query: 656 KGGNIGAKWTIDLKSGSGKVYQGPAK--GAADTTIILSDEDFMEVVLGKLDPQKAFFSGR 713
GG + +W +DLK+ KVY+GP + G ADTT+ ++D D +E+ LGKL PQ AF G+
Sbjct: 644 SGGKVAKEWVLDLKNA--KVYEGPVQGGGKADTTMTIADGDMIELALGKLQPQTAFMKGK 701
Query: 714 LKARGNIMLSQKLQMILKDYAKL 736
LK GNIML+QKL +LK AKL
Sbjct: 702 LKIAGNIMLAQKLAPLLKTEAKL 724
>ref|XP_786662.2| PREDICTED: similar to 17-beta-hydroxysteroid dehydrogenase type 4
[Strongylocentrotus purpuratus]
ref|XP_001188817.1| PREDICTED: similar to 17-beta-hydroxysteroid dehydrogenase type 4
[Strongylocentrotus purpuratus]
Length = 696
Score = 964 bits (2494), Expect = 0.0, Method: Composition-based stats.
Identities = 396/740 (53%), Positives = 500/740 (67%), Gaps = 52/740 (7%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MG LRFDGRV LVTGAG GLG+ YAL A RGA VVVNDLGGD G GK S+AAD+VV
Sbjct: 1 MGEELRFDGRVALVTGAGGGLGKEYALLLAARGASVVVNDLGGDRAGQGKSSMAADQVVN 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR +GG AVANYDSVE+G+K+V+TALD FGRID+V+NNAGILRDRSFARISD DWD++H
Sbjct: 61 EIRSKGGNAVANYDSVEDGDKLVQTALDNFGRIDIVINNAGILRDRSFARISDMDWDLVH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMKKQK+GRIIMTSSA+G+YGNFGQ NYSAAKLGL+G++N+L+
Sbjct: 121 RVHLRGSFMVTRAAWPHMKKQKFGRIIMTSSAAGLYGNFGQTNYSAAKLGLVGMSNTLSR 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG K NI CNTIAP A SR+T+ +MP D+ E LKP+YVAP+V +L HE C+ GG++E G
Sbjct: 181 EGIKYNILCNTIAPMAASRLTEDIMPPDIFEKLKPDYVAPMVAYLSHEECQSTGGIYECG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGW KLRW+RT G + + P T E S++ +L
Sbjct: 241 AGWAAKLRWQRTAGVNCLKPDQPYTAEQ------------------------NSMMFMLE 276
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
I+ EG A+ + + + VG S P
Sbjct: 277 SIN-EGSSEADSSPSSKGDTGGDGDDGGFNPV------------------VGVSTTQPDH 317
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGL-SINFAKVLHGEQYLELYKPLPR 419
LKF++E + DF LPTFGVI ++ L +PGL SI+ ++LHGEQYLEL KPL
Sbjct: 318 LKFLFELNEDFCVLPTFGVIPSFAALQ--NLTSVPGLESIDVTRILHGEQYLELKKPLDT 375
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGKRTSDKV 478
+ KL + +V D++DK SG VII++ SY E EL+ NQ +FLVG+GGFGGKR+S +
Sbjct: 376 SAKLTNKPMVVDIVDKKSGAVIIINANSYDENNELVIVNQNVVFLVGAGGFGGKRSSPHL 435
Query: 479 KVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFG 538
K P+R PDA L + TSL+QAALYRLSGD+NPLHIDP+FA++ GF +PILHGLC+FG
Sbjct: 436 KETAKAPSRAPDASLQEKTSLDQAALYRLSGDYNPLHIDPSFAAMGGFAQPILHGLCSFG 495
Query: 539 FSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVI 598
F++R VL+Q+A+NDVS+FKAIK RF+KPV PGQT+QT+MW+EG RIHFQ+KV ETG + I
Sbjct: 496 FASRHVLKQYANNDVSKFKAIKVRFSKPVLPGQTIQTDMWQEGTRIHFQSKVVETGAVCI 555
Query: 599 SNAYVDLAPTSGTSAKTPSEGGK--LQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITK 656
S AYVDL + PS+ L+S +F + P +VKKVN V +++IT
Sbjct: 556 SGAYVDLHGVAEQKNAAPSQPSSSGLKSEAIFSAASGMVSGA-PVLVKKVNGVIQYNITS 614
Query: 657 GGNIGAKWTIDLKSGSGKVYQGPAK-GAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLK 715
G + WTIDLK G G VY G K G AD T+ +SDEDF+ + G L PQ AF SG++K
Sbjct: 615 DGKVAGVWTIDLK-GQGAVYVGEPKSGKADVTVTISDEDFVALASGSLKPQTAFLSGKIK 673
Query: 716 ARGNIMLSQKLQMILKDYAK 735
+G IML QK+ + + + K
Sbjct: 674 VKGQIMLLQKVLPMFESFMK 693
>ref|XP_001743502.1| predicted protein [Monosiga brevicollis MX1]
gb|EDQ92216.1| predicted protein [Monosiga brevicollis MX1]
Length = 716
Score = 942 bits (2435), Expect = 0.0, Method: Composition-based stats.
Identities = 366/740 (49%), Positives = 491/740 (66%), Gaps = 32/740 (4%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
S LRFD RVV+VTGAG GLGR YALAFA+RGA VVVNDLGG G G + AAD VV+E
Sbjct: 4 ASLLRFDERVVIVTGAGNGLGREYALAFAKRGARVVVNDLGGSVSGDGSSNRAADTVVDE 63
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR GG AVANYDSV G+ VV TA+ AFGR+DVVVNNAGILRDRSF+++++ DWDI+H+
Sbjct: 64 IRAAGGTAVANYDSVVNGQAVVDTAIKAFGRVDVVVNNAGILRDRSFSKMTEGDWDIVHQ 123
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHL+GSF V+RAAW HM+KQKYGRIIMT+S +GIYGNFGQANYSAAKLGL+GL+N+LA E
Sbjct: 124 VHLKGSFAVSRAAWPHMRKQKYGRIIMTASTAGIYGNFGQANYSAAKLGLVGLSNTLAYE 183
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K NIHCN + P AGSR++ +VMPED A+KPEYVAP+VL+LCHESCE N G++E GA
Sbjct: 184 GAKYNIHCNALVPTAGSRLSASVMPEDYANAMKPEYVAPVVLFLCHESCEANRGVYETGA 243
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
GW+ L+W+RT GA ++ ++PE V+ W I DF A S
Sbjct: 244 GWVAALKWQRTEGAKLQSAESSISPEKVRDVWDSINDFATA-----------------ST 286
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIK-DPKD 360
+DS G ++ S + A+ + P SY + A +YAL VG + P++
Sbjct: 287 VDSMNGTASLAASPEANVQQFDRKQALSHRFPTTSYVVSPRNAALYALSVGCNPSAHPEE 346
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+++YEG S+F LPTF VI Q + +PGL N ++LHGEQ + +++PLP
Sbjct: 347 LRYVYEGHSEFGTLPTFAVIPAQ------VMTGLPGLRFNPMQLLHGEQSVTIHRPLPTE 400
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGKRTSDKVK 479
GKL +A D+LDKG G + I+ V + +E EL+ N FSLF+ G G FGG T+D +
Sbjct: 401 GKLVSQASFVDILDKGRGALAILKVETRAEAGELLVTNVFSLFIRGLGNFGGPSTNDAIP 460
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
V +P P V ++ T N AALYRL+GD NPLHIDP A +AGF +PILHGLCT+G
Sbjct: 461 GNVPVPQGAPTHVFSEKTPTNLAALYRLTGDVNPLHIDPEMAKVAGFQQPILHGLCTYGT 520
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
+AR V+ Q D SR ++ RFA PV+PG+TL+T MW +RIHFQT+V E ++V+S
Sbjct: 521 AARHVIAQCLGGDASRVHVVRGRFAAPVFPGETLETSMWVRSSRIHFQTRVVERDEVVLS 580
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
+ YVD+ P+S ++ S K + VFE R ++ E+V++VNAVF + +
Sbjct: 581 HGYVDIVPSSSSNPSA-SLPSKPEVVEVFE---RMQANLSQELVRQVNAVFTFALKSAQG 636
Query: 660 IGAKWTIDLKSGSGKVYQGPAK---GAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKA 716
++W +DLKSG+G ++ A+ DTT+ LS++DF+++ G+L+ +AF +LK
Sbjct: 637 SDSRWVVDLKSGAGAIHPPGAQLEGLKVDTTLKLSEDDFVKLARGQLNAMQAFMQNKLKV 696
Query: 717 RGNIMLSQKLQMILKDYAKL 736
GN+ML+QKL + + AKL
Sbjct: 697 SGNMMLAQKLSGLFQTQAKL 716
>gb|EDM14435.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_a [Rattus
norvegicus]
gb|EDM14437.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_a [Rattus
norvegicus]
Length = 582
Score = 921 bits (2382), Expect = 0.0, Method: Composition-based stats.
Identities = 480/563 (85%), Positives = 524/563 (93%), Gaps = 1/563 (0%)
Query: 145 RIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTV 204
RIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L IEGRK+NIHCNTIAPNAGSRMT+TV
Sbjct: 19 RIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVIEGRKNNIHCNTIAPNAGSRMTETV 78
Query: 205 MPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPM 264
MPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVR++N PM
Sbjct: 79 MPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRKRNQPM 138
Query: 265 TPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGF 324
TPEAV+ NW KICDF NASKP+SIQESTG IIEVL KIDSE G+S NHT + S SGF
Sbjct: 139 TPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLHKIDSE-GISQNHTGQVASADASGF 197
Query: 325 AGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQK 384
AG +G KLP FS +YTEL+ IMYALGVGAS+K+PKDLKF+YEGS+DFSCLPTFGVI+ QK
Sbjct: 198 AGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDLKFVYEGSADFSCLPTFGVIVAQK 257
Query: 385 SMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMD 444
S+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+G+LKCEAV+AD+LDKGSG+VI+MD
Sbjct: 258 SLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRSGELKCEAVIADILDKGSGIVIVMD 317
Query: 445 VYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAAL 504
VYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K AVA+P+RPPDAVL DTTSLNQAAL
Sbjct: 318 VYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAAVAVPSRPPDAVLRDTTSLNQAAL 377
Query: 505 YRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFA 564
YRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFSAR VLQQFADNDVSRFKAIK RFA
Sbjct: 378 YRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFSARHVLQQFADNDVSRFKAIKVRFA 437
Query: 565 KPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQS 624
KPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDL PTSG SA+TPSEGG LQS
Sbjct: 438 KPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLVPTSGVSAQTPSEGGALQS 497
Query: 625 TFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAA 684
VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+ AKWTIDLK+GSG+VYQGPAKG+A
Sbjct: 498 ALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVAAKWTIDLKNGSGEVYQGPAKGSA 557
Query: 685 DTTIILSDEDFMEVVLGKLDPQK 707
DTTI +SDEDFMEVVLGKL+PQ
Sbjct: 558 DTTITISDEDFMEVVLGKLNPQN 580
>dbj|BAD51963.1| 17-beta hydroxysteroid dehydrogenase 4 [Macaca fascicularis]
Length = 499
Score = 813 bits (2102), Expect = 0.0, Method: Composition-based stats.
Identities = 473/481 (98%), Positives = 477/481 (99%), Gaps = 1/481 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVA+YDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 61 EIRRRGGKAVASYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE GVSANHTS ATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
Sbjct: 301 KIDSE-GVSANHTSHATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGSSDFSCLPTFGVIIGQKS+MGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
Sbjct: 360 LKFVYEGSSDFSCLPTFGVIIGQKSLMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK
Sbjct: 420 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKP 479
Query: 481 A 481
Sbjct: 480 T 480
>ref|XP_001400728.1| hypothetical protein An14g00990 [Aspergillus niger]
emb|CAK41898.1| unnamed protein product [Aspergillus niger]
Length = 901
Score = 806 bits (2084), Expect = 0.0, Method: Composition-based stats.
Identities = 283/623 (45%), Positives = 385/623 (61%), Gaps = 40/623 (6%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
G F G+V LVTG G GLGRAY L FA+ GA VVVNDL + + VV+E
Sbjct: 306 GEEPNFKGKVALVTGGGNGLGRAYCLLFAKYGASVVVNDL-----------VDPEPVVQE 354
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
I++ GG+AV N S E+GE VVKTA+DAFGRID+++NNAGILRD++F ++D+ W+ +
Sbjct: 355 IKKMGGQAVGNKASCEDGENVVKTAIDAFGRIDILINNAGILRDKAFTNMNDDLWNPVLN 414
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHLRG+++VT+AAW +M KQKYGRI+ T+S SGIYGNFGQANY+AAKLG+LG + +LA+E
Sbjct: 415 VHLRGTYKVTKAAWPYMLKQKYGRIVNTASTSGIYGNFGQANYAAAKLGILGFSRTLALE 474
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEE--NGGLFEV 239
G K NI NTIAPNAG+ MT+T+MPE++V+A KP+YVAPLV LC + E GL+E
Sbjct: 475 GAKYNIKVNTIAPNAGTNMTRTIMPEEMVQAFKPDYVAPLVALLCSDIVPEPSTKGLYEC 534
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN--ASKPQSIQESTGSIIE 297
G+GW G+ RW+RT G + +TPE V NWKKI +F++ A P+ Q + I+
Sbjct: 535 GSGWFGRTRWQRT-GGHGFPVDVKLTPEEVLKNWKKITNFDDGRADHPEDGQAGSEKIMA 593
Query: 298 VLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
+S N +A A S+ Y + + I+Y L +GA
Sbjct: 594 NMSNRSGGDSEGGNKILQA-------IEKAKQATTDGTSFDYEDRDVILYNLSLGAK--- 643
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYK-P 416
DL +YE + F LPT+GVI + + EI + + +LHGEQY+E+ K P
Sbjct: 644 RTDLPLVYENNEHFQALPTYGVIPWFNTANPWNMDEIVA-NFSPMMLLHGEQYMEIRKFP 702
Query: 417 LPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYS--EKELICHNQFSLFLVGSGGFGG--K 472
+P A K + DV+DKG+ +++ + E + +N+ ++F+ GSGGFGG K
Sbjct: 703 IPTAAKTLTYPKLIDVVDKGNAALVVSGYTTKDAKTGEDLFYNESTVFIRGSGGFGGSPK 762
Query: 473 RTSDKVKVAVA---IPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKP 529
T+ + K AVA P R PDAV+ + TS +QAALYRL+GD NPLHIDP F+ + GF P
Sbjct: 763 PTARRPKAAVASYKAPQRKPDAVVEEKTSEDQAALYRLNGDRNPLHIDPEFSKVGGFKTP 822
Query: 530 ILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK 589
ILHGLC+ G S + V + FK +K RF+ V PGQTL+TEMWKEGN + FQT
Sbjct: 823 ILHGLCSLGVSGKHVFSTYG-----AFKNLKVRFSGVVLPGQTLRTEMWKEGNVVLFQTT 877
Query: 590 VQETGDIVISNAYVDLAPTSGTS 612
V +TG I+ A +L +
Sbjct: 878 VVDTGKPAITGAGAELLEGAKAK 900
Score = 439 bits (1130), Expect = e-121, Method: Composition-based stats.
Identities = 172/329 (52%), Positives = 221/329 (67%), Gaps = 4/329 (1%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
S LRFD + V+VTGAG GLG+AYAL FA RGA VVVNDLGG G GK + AAD VVEEI
Sbjct: 2 SELRFDNQTVVVTGAGGGLGKAYALFFASRGANVVVNDLGGSHSGEGKSAKAADVVVEEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R GGKAVANYDSVE GE +++TA+ FGRIDV++NNAGILRD SF + D+DWD+I+RV
Sbjct: 62 RAAGGKAVANYDSVENGEAIIETAIKNFGRIDVLLNNAGILRDISFKNMKDQDWDLIYRV 121
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
H G+++ RAAW H +KQKYGRII T+S++G++G+FGQANYSAAKLG +G +LA EG
Sbjct: 122 HTYGAYKCARAAWPHFRKQKYGRIINTASSAGLFGSFGQANYSAAKLGQVGFTETLAKEG 181
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESC-EENGGLFEVGA 241
K NI N IAP A SRMT TVMP +++E LKP++V PLV L H S E GG++EVG
Sbjct: 182 AKYNIIANVIAPIAASRMTATVMPPEVLENLKPDWVVPLVAALVHSSNTTETGGIYEVGG 241
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
G + KLRWER GA+++ + +TP A+ W + DF P + ++E K
Sbjct: 242 GHVAKLRWERAKGALLKT-DASLTPGAIARKWNDVNDFSQPDYPTGPAD-FMGLLEDGLK 299
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQ 330
+ S + +G +G+
Sbjct: 300 LPS-AQAGEEPNFKGKVALVTGGGNGLGR 327
>ref|NP_573109.1| CG3415 CG3415-PA [Drosophila melanogaster]
gb|AAF48572.1| CG3415-PA [Drosophila melanogaster]
gb|AAK92917.1| GH14720p [Drosophila melanogaster]
Length = 598
Score = 802 bits (2072), Expect = 0.0, Method: Composition-based stats.
Identities = 320/620 (51%), Positives = 418/620 (67%), Gaps = 32/620 (5%)
Query: 1 MGSP---LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADK 57
M S LR+DGRV +VTGAGAGLGR YAL FAERGA VVVNDLGG G G AAD
Sbjct: 1 MSSSDGKLRYDGRVAVVTGAGAGLGREYALLFAERGAKVVVNDLGGTHSGDGASQRAADI 60
Query: 58 VVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWD 117
VV+EIR+ GG+AVA+Y+SV +G KV++TA+ AFGR+D++VNNAGILRDRS + S++DW+
Sbjct: 61 VVDEIRKAGGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGILRDRSLVKTSEQDWN 120
Query: 118 IIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANS 177
+++ VHL+GSF+ T+AA+ +MKKQ YGRIIMTSS SGIYGNFGQ NY+AAK+GL+GLAN+
Sbjct: 121 LVNDVHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMGLIGLANT 180
Query: 178 LAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLF 237
+AIEG ++N+ CN I P A SRMT+ ++P+ L LKP+ +AP+V +LCHESCE+NG
Sbjct: 181 VAIEGARNNVLCNVIVPTAASRMTEGILPDILFNELKPKLIAPVVAYLCHESCEDNGSYI 240
Query: 238 EVGAGWIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSII 296
E AGW KL R GA++R + P+T E VK W + D A +I E++G+++
Sbjct: 241 ESAAGWATKLHMVRGKGAVLRPSLDDPVTIEYVKDVWSNVTDMSKAKHLGAIAEASGTLL 300
Query: 297 EVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIK 356
EVL K+ GG + + + E I YALG+GAS+K
Sbjct: 301 EVLEKLKEGGGDAIEDA-----------------------FEFNSKELITYALGIGASVK 337
Query: 357 DPKDLKFIYEGSSDFSCLPTFGVIIG---QKSMMGGGLAEIPGLSINFAKVLHGEQYLEL 413
+ KD++F+YE +DF+ +PTF V+ G Q S +P ++F+ +LHGEQYLE+
Sbjct: 338 NAKDMRFLYENDADFAAIPTFFVLPGLLLQMSTDKLLSKALPNSQVDFSNILHGEQYLEI 397
Query: 414 YKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGK 472
LP +G L V DV+DKGSG V++ + S+ E L+ NQ + F+VG+G FGGK
Sbjct: 398 VDDLPTSGTLLTNGKVFDVMDKGSGAVVVTNSESFDESGRLLVRNQSTTFIVGAGKFGGK 457
Query: 473 RTS-DKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPIL 531
+ V PNR PDA + TTS +QAALYRLSGD NPLHIDP A LAGF PIL
Sbjct: 458 KDPIAGVVPLQPAPNRQPDATVQYTTSEDQAALYRLSGDKNPLHIDPQMALLAGFKTPIL 517
Query: 532 HGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQ 591
HGLCT GFS R VL QFADN+ + FKA+K RF+ PV PGQTL+ ++WK+G RI+F+T V
Sbjct: 518 HGLCTLGFSVRAVLAQFADNNPALFKAVKVRFSGPVIPGQTLRVDLWKQGTRINFRTVVV 577
Query: 592 ETGDIVISNAYVDLAPTSGT 611
ETG VIS AYVDL +
Sbjct: 578 ETGKEVISGAYVDLKSSQAK 597
>ref|XP_746577.1| peroxisomal multifunctional beta-oxidation protein (MFP), putative
[Aspergillus fumigatus Af293]
gb|EAL84539.1| peroxisomal multifunctional beta-oxidation protein (MFP), putative
[Aspergillus fumigatus Af293]
gb|EDP47311.1| peroxisomal multifunctional beta-oxidation protein (MFP), putative
[Aspergillus fumigatus A1163]
Length = 899
Score = 801 bits (2070), Expect = 0.0, Method: Composition-based stats.
Identities = 282/623 (45%), Positives = 381/623 (61%), Gaps = 42/623 (6%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
G G+V LVTG G GLGR+Y L FA+ GA VVVNDL + + VV+E
Sbjct: 306 GEEPDLKGKVALVTGGGNGLGRSYCLLFAKLGASVVVNDL-----------VDPEPVVQE 354
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
I++ GGKAV N S E+G+ VVKTA+DAFGRID++VNNAGILRD++F ++D+ W+ +
Sbjct: 355 IKKMGGKAVGNKASCEDGDAVVKTAIDAFGRIDILVNNAGILRDKAFTNMNDDLWNAVIN 414
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHLRG+++VT+AAW HM KQKYGRI+ T+S SGIYGNFGQANY+AAKLG+LG + +LAIE
Sbjct: 415 VHLRGTYKVTKAAWPHMLKQKYGRIVNTTSTSGIYGNFGQANYAAAKLGILGFSRALAIE 474
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEE--NGGLFEV 239
G K NI NTIAPNAG+ MT+T+MPE++V+A KP+YVAP+V LC + C E + GL+E
Sbjct: 475 GAKYNIKVNTIAPNAGTNMTRTIMPEEMVQAFKPDYVAPMVALLCSDMCPEPSSKGLYEC 534
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN--ASKPQSIQESTGSIIE 297
G+GW RW+R+ G + +TPE V NWK+I DF++ A PQ Q T ++
Sbjct: 535 GSGWFSSTRWQRS-GGHGFPVDVKLTPETVLKNWKQITDFDDGRADHPQDSQAGTEKVMA 593
Query: 298 VLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
+S G + + A ++ Y + + I+Y L VGA
Sbjct: 594 NMSNRSGGEG---------GNNILANIEKAKQATTEGTAFDYIDRDIILYNLSVGAK--- 641
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYK-P 416
DL +YE + F LPTFGVI + + +I + + +LHGEQY+E+ K P
Sbjct: 642 RTDLPLVYENNEHFQALPTFGVIPWFNTATPWNMDDIVA-NFSPMMLLHGEQYMEIRKFP 700
Query: 417 LPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYS--EKELICHNQFSLFLVGSGGFGG--K 472
+P K + DV+DKG +++ + E + +N+ ++F+ GSGGFGG K
Sbjct: 701 IPTEAKTLTYPKLIDVVDKGKAALVVAGYTTKDAKTGEDLFYNESTVFIRGSGGFGGSPK 760
Query: 473 RTSDKVKVAVA---IPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKP 529
T+ + K A A P R PD V+ + TS +QAALYRL+GD NPLHIDP F+ + GF P
Sbjct: 761 PTASRPKGATAAYNPPKRQPDVVIEEKTSEDQAALYRLNGDRNPLHIDPEFSKVGGFKTP 820
Query: 530 ILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK 589
ILHGLC+ G S + V +F FK++K RFA V PGQTL+TEMWKEGN + FQT
Sbjct: 821 ILHGLCSLGISGKHVFNKFG-----AFKSLKVRFAGVVLPGQTLKTEMWKEGNTVIFQTT 875
Query: 590 VQETGDIVISNAYVDLAPTSGTS 612
V ETG I A +L +
Sbjct: 876 VVETGKPAILGAGAELLEGAKAK 898
Score = 431 bits (1110), Expect = e-119, Method: Composition-based stats.
Identities = 170/329 (51%), Positives = 219/329 (66%), Gaps = 4/329 (1%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
S LRFD + V+VTGAG GLG+AYA FA RGA VVVNDLG G G S AAD VVEEI
Sbjct: 2 SELRFDNQTVVVTGAGGGLGKAYATFFASRGANVVVNDLGVSHSGEGASSKAADVVVEEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R GGKAVANYDSVE GE +++TA+ FGRIDV++NNAGILRD SF + D+DWD+I++V
Sbjct: 62 RAAGGKAVANYDSVENGEAIIETAIKNFGRIDVLINNAGILRDVSFKNMKDQDWDLINKV 121
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
H G+++ RAAW H +KQKYGRII T+SA+G++GNFGQANYSAAKLG +G +LA EG
Sbjct: 122 HTYGAYKCARAAWPHFRKQKYGRIINTASAAGLFGNFGQANYSAAKLGQVGFTETLAKEG 181
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESC-EENGGLFEVGA 241
K NI N IAP A SRMT T+MP +++E LKP++V PLV L H S E+G +FEVG
Sbjct: 182 AKYNIIANVIAPIAASRMTATIMPPEVLENLKPDWVVPLVAVLVHPSNTTESGSIFEVGG 241
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
G + KLRWER GA+++ + +TP A+ WK + D+ P + +++E K
Sbjct: 242 GHMAKLRWERAKGALLKT-DASLTPGAIARKWKDVYDYSQPEYPIGPAD-FMTLLENGMK 299
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQ 330
S + +G +G+
Sbjct: 300 TPS-APAGEEPDLKGKVALVTGGGNGLGR 327
>ref|XP_001262415.1| peroxisomal multifunctional beta-oxidation protein (MFP), putative
[Neosartorya fischeri NRRL 181]
gb|EAW20518.1| peroxisomal multifunctional beta-oxidation protein (MFP), putative
[Neosartorya fischeri NRRL 181]
Length = 899
Score = 800 bits (2067), Expect = 0.0, Method: Composition-based stats.
Identities = 283/623 (45%), Positives = 382/623 (61%), Gaps = 42/623 (6%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
G G+V LVTG G GLGR+Y L FA+ GA VVVNDL + + VV+E
Sbjct: 306 GEEPDLKGKVALVTGGGNGLGRSYCLLFAKLGASVVVNDL-----------VDPEPVVQE 354
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
I++ GGKAV N S E+G+ VVKTA+DAFGRID++VNNAGILRD++F ++D+ W+ +
Sbjct: 355 IKKMGGKAVGNKASCEDGDAVVKTAIDAFGRIDILVNNAGILRDKAFTNMNDDLWNAVIH 414
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHLRG+++VT+AAW HM KQKYGRI+ T+S SGIYGNFGQANY+AAKLG+LGL+ +LAIE
Sbjct: 415 VHLRGTYKVTKAAWPHMLKQKYGRIVNTASTSGIYGNFGQANYAAAKLGILGLSRALAIE 474
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEE--NGGLFEV 239
G K NI NTIAPNAG+ MT+T+MPE++V+A KP+YVAP+V LC + C E + GL+E
Sbjct: 475 GAKYNIKVNTIAPNAGTNMTRTIMPEEMVQAFKPDYVAPMVALLCSDMCPEPSSKGLYEC 534
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN--ASKPQSIQESTGSIIE 297
G+GW RW+R+ G + +TPEAV NWK+I DF++ A P+ Q T ++
Sbjct: 535 GSGWFSSTRWQRS-GGHGFPVDVKLTPEAVLKNWKQITDFDDGRADHPEDSQAGTEKVMA 593
Query: 298 VLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
+S G + + A ++ Y + + I+Y L VGA
Sbjct: 594 NMSNRSGGEG---------GNDILANIEKAKQATTEGTAFDYVDRDVILYNLSVGAK--- 641
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYK-P 416
DL +YE + F LPTFGVI + + +I + + +LHGEQY+E+ K P
Sbjct: 642 RTDLPLVYENNEHFQALPTFGVIPWFNTATPWNMDDIVA-NFSPMMLLHGEQYMEVRKFP 700
Query: 417 LPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYS--EKELICHNQFSLFLVGSGGFGG--K 472
+P K + DV+DKG +++ + E + +N+ ++F+ GSGGFGG K
Sbjct: 701 IPTEAKTLTYPKLIDVVDKGKAALVVAGYTTKDAKTGEDLFYNESTVFIRGSGGFGGSPK 760
Query: 473 RTSDKVKVAVA---IPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKP 529
T+ + K A A P R PD V+ + TS +QAALYRL+GD NPLHIDP F+ + GF P
Sbjct: 761 PTAPRPKGATAAYNPPKRQPDVVIEEKTSEDQAALYRLNGDRNPLHIDPEFSKVGGFKTP 820
Query: 530 ILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK 589
ILHGLC+ G S + V +F FK +K RFA V PGQTL+TEMWKEGN + FQT
Sbjct: 821 ILHGLCSLGVSGKHVFNKFG-----AFKNLKVRFAGVVLPGQTLKTEMWKEGNTVIFQTT 875
Query: 590 VQETGDIVISNAYVDLAPTSGTS 612
V ETG I A +L +
Sbjct: 876 VVETGKPAILGAGAELLEGAKAK 898
Score = 432 bits (1113), Expect = e-119, Method: Composition-based stats.
Identities = 170/329 (51%), Positives = 219/329 (66%), Gaps = 4/329 (1%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
S LRFD + V+VTGAG GLG+AYA FA RGA VVVNDLG G G S AAD VVEEI
Sbjct: 2 SELRFDNQTVVVTGAGGGLGKAYATFFASRGANVVVNDLGVSHSGEGASSKAADVVVEEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R GGKAVANYDSVE GE +++TA+ FGRIDV++NNAGILRD SF + D+DWD+I++V
Sbjct: 62 RAAGGKAVANYDSVENGEAIIETAIKNFGRIDVLINNAGILRDVSFKNMKDQDWDLINKV 121
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
H G+++ RAAW H +KQKYGRII T+SA+G++GNFGQANYSAAKLG +G +LA EG
Sbjct: 122 HTYGAYKCARAAWPHFRKQKYGRIINTASAAGLFGNFGQANYSAAKLGQVGFTETLAKEG 181
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESC-EENGGLFEVGA 241
K NI N IAP A SRMT T+MP +++E LKP+++ PLV L H S E+G +FEVG
Sbjct: 182 AKYNIIANVIAPIAASRMTATIMPPEVLENLKPDWIVPLVAVLVHPSNTTESGSIFEVGG 241
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
G + KLRWER GA+++ + +TP A+ WK + D+ P + S++E K
Sbjct: 242 GHMAKLRWERAKGALLKT-DASLTPGAIARKWKDVYDYSQPEYPTGPAD-FMSLLENGMK 299
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQ 330
S + +G +G+
Sbjct: 300 TPS-APTGEEPDLKGKVALVTGGGNGLGR 327
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|NP_000405.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1263 0.0
ref|XP_001087837.1| PREDICTED: hydroxysteroid (17-beta) deh... 1226 0.0
ref|XP_531860.2| PREDICTED: similar to Peroxisomal multifun... 1210 0.0
ref|NP_001075370.1| 17 beta-hydroxysteroid dehydrogenase ty... 1210 0.0
gb|AAI22585.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Bo... 1209 0.0
ref|XP_859341.1| PREDICTED: similar to Peroxisomal multifun... 1204 0.0
ref|NP_001007810.1| hydroxysteroid (17-beta) dehydrogenase ... 1204 0.0
ref|NP_077368.2| hydroxysteroid (17-beta) dehydrogenase 4 [... 1200 0.0
ref|XP_859306.1| PREDICTED: similar to Peroxisomal multifun... 1200 0.0
ref|XP_517892.2| PREDICTED: hydroxysteroid (17-beta) dehydr... 1197 0.0
gb|AAB09724.1| peroxisomal multifunctional enzyme type II 1193 0.0
ref|NP_032318.2| hydroxysteroid (17-beta) dehydrogenase 4 [... 1192 0.0
dbj|BAE36514.1| unnamed protein product [Mus musculus] 1190 0.0
gb|AAH72472.1| Hsd17b4 protein [Rattus norvegicus] 1189 0.0
dbj|BAE27744.1| unnamed protein product [Mus musculus] 1187 0.0
emb|CAA62015.1| 17beta-hydroxysteroid dehydrogenase IV [Mus... 1184 0.0
emb|CAA64427.1| multifunctional protein 2 [Rattus norvegicus] 1182 0.0
emb|CAA73945.1| mutifunctional protein2 [Cavia porcellus] 1175 0.0
ref|NP_999471.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1174 0.0
gb|EDL09934.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 1164 0.0
dbj|BAF74749.1| hydroxysteroid (17-beta) dehydrogenase 4 [F... 1153 0.0
ref|NP_001027490.1| hypothetical protein LOC613082 [Xenopus... 1150 0.0
gb|EDM14436.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 1141 0.0
ref|NP_990274.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1135 0.0
ref|NP_001086063.1| MGC81885 protein [Xenopus laevis] >gi|4... 1131 0.0
ref|XP_001378211.1| PREDICTED: similar to 17beta-hydroxyste... 1118 0.0
gb|AAK27967.1|AF241285_1 17-beta-hydroxysteroid dehydrogena... 1111 0.0
ref|NP_956430.1| hydroxysteroid (17-beta) dehydrogenase 4 [... 1111 0.0
gb|AAH65945.1| Hsd17b4 protein [Danio rerio] 1107 0.0
ref|XP_001512505.1| PREDICTED: similar to 17beta-hydroxyste... 1082 0.0
ref|XP_001624936.1| predicted protein [Nematostella vectens... 1051 0.0
gb|EAW48910.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 1013 0.0
ref|XP_001606624.1| PREDICTED: similar to estradiol 17 beta... 1008 0.0
ref|XP_001652466.1| estradiol 17 beta-dehydrogenase [Aedes ... 1000 0.0
emb|CAB55552.1| Fox2 protein [Glomus mosseae] 995 0.0
ref|XP_393475.2| PREDICTED: similar to Peroxisomal multifun... 993 0.0
ref|XP_001088200.1| PREDICTED: hydroxysteroid (17-beta) deh... 992 0.0
ref|XP_001843060.1| peroxisomal multifunctional enzyme type... 991 0.0
emb|CAG09600.1| unnamed protein product [Tetraodon nigrovir... 989 0.0
ref|XP_974784.1| PREDICTED: similar to Peroxisomal multifun... 987 0.0
ref|XP_859266.1| PREDICTED: similar to Peroxisomal multifun... 983 0.0
ref|XP_314766.4| AGAP008667-PA [Anopheles gambiae str. PEST... 982 0.0
ref|XP_786662.2| PREDICTED: similar to 17-beta-hydroxystero... 972 0.0
ref|XP_001743502.1| predicted protein [Monosiga brevicollis... 951 0.0
gb|EDM14435.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 892 0.0
ref|XP_001400728.1| hypothetical protein An14g00990 [Asperg... 831 0.0
ref|XP_746577.1| peroxisomal multifunctional beta-oxidation... 830 0.0
ref|XP_001262415.1| peroxisomal multifunctional beta-oxidat... 827 0.0
ref|XP_001211399.1| acetoacetyl-CoA reductase [Aspergillus ... 823 0.0
ref|XP_001241529.1| hypothetical protein CIMG_08692 [Coccid... 821 0.0
ref|XP_001274833.1| peroxisomal multifunctional beta-oxidat... 818 0.0
ref|XP_389819.1| FOX2_NEUCR Peroxisomal hydratase-dehydroge... 817 0.0
ref|XP_369316.1| peroxisomal hydratase-dehydrogenase-epimer... 817 0.0
ref|XP_001825975.1| hypothetical protein [Aspergillus oryza... 816 0.0
ref|NP_573109.1| CG3415 CG3415-PA [Drosophila melanogaster]... 815 0.0
ref|XP_001906707.1| unnamed protein product [Podospora anse... 814 0.0
ref|XP_962039.1| peroxisomal hydratase-dehydrogenase-epimer... 811 0.0
ref|XP_001536930.1| hypothetical protein HCAG_08039 [Ajello... 809 0.0
gb|EDU44349.1| peroxisomal multifunctional enzyme type 2 [P... 808 0.0
ref|XP_001223046.1| peroxisomal hydratase-dehydrogenase-epi... 806 0.0
gb|EEH44993.1| peroxisomal multifunctional enzyme [Paracocc... 805 0.0
ref|XP_001589313.1| hypothetical protein SS1G_09947 [Sclero... 801 0.0
gb|EEH40042.1| peroxisomal multifunctional enzyme [Paracocc... 801 0.0
ref|XP_001545846.1| hypothetical protein BC1G_15684 [Botryo... 800 0.0
ref|XP_001355058.1| GA17436-PA [Drosophila pseudoobscura] >... 788 0.0
ref|XP_503980.1| hypothetical protein [Yarrowia lipolytica]... 788 0.0
ref|XP_001803860.1| hypothetical protein SNOG_13654 [Phaeos... 786 0.0
dbj|BAD51963.1| 17-beta hydroxysteroid dehydrogenase 4 [Mac... 777 0.0
ref|XP_664715.1| hypothetical protein AN7111.2 [Aspergillus... 776 0.0
ref|XP_756297.1| hypothetical protein UM00150.1 [Ustilago m... 771 0.0
dbj|BAD92169.1| hydroxysteroid (17-beta) dehydrogenase 4 va... 767 0.0
ref|XP_001880676.1| multifunctional beta-oxidation protein ... 760 0.0
ref|XP_571589.1| peroxisomal hydratase-dehydrogenase-epimer... 750 0.0
ref|XP_001484143.1| hypothetical protein PGUG_03524 [Pichia... 746 0.0
ref|XP_001087962.1| PREDICTED: hydroxysteroid (17-beta) deh... 745 0.0
ref|XP_001527383.1| peroxisomal hydratase-dehydrogenase-epi... 726 0.0
sp|P22414|FOX2_CANTR Peroxisomal hydratase-dehydrogenase-ep... 723 0.0
ref|XP_710072.1| peroxisomal hydratase-dehydrogenase-epimer... 723 0.0
ref|XP_001383009.1| hypothetical protein PICST_54590 [Pichi... 722 0.0
gb|AAA62847.1| hydratase-dehydrogenase-epimerase 719 0.0
ref|XP_456704.1| hypothetical protein DEHA0A08778g [Debaryo... 714 0.0
ref|XP_001642757.1| hypothetical protein Kpol_348p3 [Vander... 712 0.0
ref|XP_001729772.1| hypothetical protein MGL_3316 [Malassez... 697 0.0
ref|XP_454574.1| unnamed protein product [Kluyveromyces lac... 697 0.0
ref|NP_986606.1| AGL060Wp [Ashbya gossypii ATCC 10895] >gi|... 668 0.0
ref|XP_448864.1| unnamed protein product [Candida glabrata]... 663 0.0
ref|NP_012934.1| Multifunctional enzyme of the peroxisomal ... 637 0.0
gb|EDN59917.1| multifunctional beta-oxidation protein [Sacc... 636 e-180
pdb|1ZBQ|A Chain A, Crystal Structure Of Human 17-Beta-Hydr... 518 e-145
pdb|1S9C|A Chain A, Crystal Structure Analysis Of The 2-Eno... 509 e-142
gb|EDL09933.1| hydroxysteroid (17-beta) dehydrogenase 4, is... 505 e-141
dbj|BAE90061.1| unnamed protein product [Macaca fascicularis] 504 e-141
pdb|1GZ6|A Chain A, (3r)-Hydroxyacyl-Coa Dehydrogenase Frag... 496 e-138
ref|YP_001188762.1| short-chain dehydrogenase/reductase SDR... 477 e-132
ref|YP_001670829.1| short-chain dehydrogenase/reductase SDR... 475 e-132
ref|YP_610072.1| oxidoreductase, short chain dehydrogenase/... 472 e-131
ref|YP_001171638.1| probable short-chain dehydrogenase [Pse... 470 e-130
ref|XP_001253030.1| PREDICTED: similar to Multifunctional p... 470 e-130
ref|YP_001747689.1| short-chain dehydrogenase/reductase SDR... 468 e-130
ref|YP_346635.1| Short-chain dehydrogenase/reductase SDR [P... 467 e-129
ref|YP_273346.1| oxidoreductase, short chain dehydrogenase/... 467 e-129
ref|YP_258092.1| oxidoreductase, short chain dehydrogenase/... 467 e-129
ref|YP_234119.1| Short-chain dehydrogenase/reductase SDR [P... 466 e-129
ref|NP_791019.1| oxidoreductase, short chain dehydrogenase/... 466 e-129
ref|NP_252117.1| probable short-chain dehydrogenases [Pseud... 465 e-129
gb|AAT51203.1| PA3427 [synthetic construct] 465 e-129
ref|YP_001347083.1| probable short-chain dehydrogenase [Pse... 464 e-128
prf||2018258A 17beta-estradiol dehydrogenase 459 e-127
ref|XP_001455301.1| hypothetical protein GSPATT00021528001 ... 450 e-124
gb|ABY59724.1| D-bifunctional protein [Toxoplasma gondii] 445 e-123
ref|XP_001457027.1| hypothetical protein GSPATT00022802001 ... 444 e-122
ref|XP_635235.1| hypothetical protein DDB_0201628 [Dictyost... 442 e-122
ref|YP_001529431.1| short-chain dehydrogenase/reductase SDR... 439 e-121
gb|EEJ95553.1| dehydrogenase of unknown specificity similar... 439 e-121
ref|ZP_02134354.1| short-chain dehydrogenase/reductase SDR ... 439 e-121
ref|ZP_01615241.1| Short-chain dehydrogenase/reductase SDR ... 439 e-121
ref|XP_001021425.1| acyl carrier protein reductase [Tetrahy... 439 e-121
ref|YP_457088.1| probable short-chain dehydrogenase [Erythr... 438 e-121
ref|NP_509146.1| DeHydrogenases, Short chain family member ... 434 e-119
ref|YP_692674.1| oxidoreductase [Alcanivorax borkumensis SK... 434 e-119
ref|XP_001676977.1| Hypothetical protein CBG10899 [Caenorha... 433 e-119
ref|ZP_02131456.1| short-chain dehydrogenase/reductase SDR ... 431 e-119
gb|AAS21352.1| 17-beta-hydroxysteroid dehydrogenase type IV... 430 e-118
pdb|2CDH|S Chain S, Architecture Of The Thermomyces Lanugin... 430 e-118
ref|YP_001529430.1| short-chain dehydrogenase/reductase SDR... 425 e-117
ref|YP_001412346.1| short-chain dehydrogenase/reductase SDR... 423 e-116
ref|NP_495494.1| E04F6.3 [Caenorhabditis elegans] >gi|86133... 422 e-116
ref|ZP_02131455.1| short-chain dehydrogenase/reductase SDR ... 422 e-116
ref|ZP_01103376.1| Short-chain dehydrogenase/reductase SDR ... 420 e-115
emb|CAP31946.1| C. briggsae CBR-MAOC-1 protein [Caenorhabdi... 419 e-115
pdb|2ET6|A Chain A, (3r)-Hydroxyacyl-Coa Dehydrogenase Doma... 419 e-115
ref|ZP_01223710.1| oxidoreductase, short chain dehydrogenas... 414 e-113
ref|ZP_00952848.1| possible 3-oxo-(acyl) acyl carrier prote... 414 e-113
ref|YP_750748.1| short-chain dehydrogenase/reductase SDR [S... 413 e-113
ref|YP_001239580.1| putative 3-oxo-(acyl) acyl carrier prot... 412 e-113
ref|ZP_01616123.1| oxidoreductase, short chain dehydrogenas... 411 e-112
ref|YP_486812.1| Short-chain dehydrogenase/reductase SDR [R... 410 e-112
ref|YP_367244.1| Short-chain dehydrogenase/reductase SDR [B... 410 e-112
ref|YP_458654.1| possible 3-oxo-(acyl) acyl carrier protein... 410 e-112
ref|ZP_02298781.1| short-chain dehydrogenase/reductase SDR ... 410 e-112
ref|NP_947531.1| possible 3-oxo-(acyl) acyl carrier protein... 409 e-112
ref|YP_756878.1| short-chain dehydrogenase/reductase SDR [M... 409 e-112
ref|YP_001205176.1| putative 3-oxo-(acyl) acyl carrier prot... 409 e-112
ref|NP_770600.1| probable short-chain dehydrogenase [Bradyr... 408 e-112
ref|ZP_01040272.1| Short-chain dehydrogenase/reductase SDR ... 408 e-112
ref|ZP_01519585.1| short-chain dehydrogenase/reductase SDR ... 407 e-111
ref|YP_569386.1| short-chain dehydrogenase/reductase SDR [R... 406 e-111
ref|YP_001684966.1| short-chain dehydrogenase/reductase SDR... 406 e-111
ref|YP_615585.1| short-chain dehydrogenase/reductase SDR [S... 405 e-111
ref|YP_884263.1| peroxisomal multifunctional enzyme type 2 ... 405 e-111
ref|XP_001836310.1| hypothetical protein CC1G_06395 [Coprin... 405 e-111
gb|AAT47756.1| probable short-chain dehydrogenase [Mycobact... 405 e-111
ref|ZP_01864417.1| possible 3-oxo-(acyl) acyl carrier prote... 403 e-110
ref|YP_884512.1| peroxisomal hydratase-dehydrogenase-epimer... 403 e-110
ref|NP_420896.1| 3-oxoacyl-(acyl-carrier-protein) reductase... 403 e-110
ref|YP_001563493.1| short-chain dehydrogenase/reductase SDR... 403 e-110
ref|XP_001836311.1| hypothetical protein CC1G_06396 [Coprin... 403 e-110
ref|ZP_02190724.1| MaoC-like dehydratase [alpha proteobacte... 403 e-110
ref|YP_167200.1| oxidoreductase, short chain dehydrogenase/... 401 e-110
ref|NP_334566.1| oxidoreductase, short-chain dehydrogenase/... 401 e-109
ref|NP_962501.1| hypothetical protein MAP3567 [Mycobacteriu... 400 e-109
ref|NP_214662.1| PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/RE... 400 e-109
ref|ZP_01225010.1| oxidoreductase, short chain dehydrogenas... 400 e-109
ref|YP_001068385.1| short-chain dehydrogenase/reductase SDR... 400 e-109
ref|YP_986758.1| short-chain dehydrogenase/reductase SDR [A... 400 e-109
gb|ABI95866.1| 17-beta-hydroxysteroid dehydrogenase type 4 ... 400 e-109
ref|XP_001426526.1| hypothetical protein GSPATT00029759001 ... 400 e-109
ref|XP_001440682.1| hypothetical protein GSPATT00009600001 ... 398 e-109
ref|YP_001888840.1| short-chain dehydrogenase/reductase SDR... 398 e-109
ref|YP_781309.1| short-chain dehydrogenase/reductase SDR [R... 397 e-108
ref|XP_001433168.1| hypothetical protein GSPATT00006270001 ... 397 e-108
ref|YP_950963.1| short-chain dehydrogenase/reductase SDR [M... 397 e-108
ref|YP_532949.1| short-chain dehydrogenase/reductase SDR [R... 397 e-108
ref|YP_001508763.1| short-chain dehydrogenase/reductase SDR... 397 e-108
ref|ZP_02887245.1| short-chain dehydrogenase/reductase SDR ... 395 e-108
ref|YP_001132014.1| short-chain dehydrogenase/reductase SDR... 395 e-108
ref|YP_637269.1| short-chain dehydrogenase/reductase SDR [M... 394 e-107
ref|ZP_01626410.1| possible 3-oxo-(acyl) acyl carrier prote... 394 e-107
ref|YP_761498.1| oxidoreductase, short chain dehydrogenase/... 394 e-107
ref|YP_001411770.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-b... 392 e-107
ref|YP_497943.1| short-chain dehydrogenase/reductase SDR [N... 390 e-106
ref|ZP_00956517.1| oxidoreductase, short chain dehydrogenas... 390 e-106
ref|ZP_00963728.1| oxidoreductase, short chain dehydrogenas... 390 e-106
ref|YP_552039.1| MaoC-like dehydratase [Polaromonas sp. JS6... 390 e-106
ref|YP_001705327.1| Putative short-chain dehydrogenase/redu... 390 e-106
ref|ZP_00998756.1| oxidoreductase, short chain dehydrogenas... 389 e-106
gb|EEJ94366.1| dehydrogenase of unknown specificity similar... 385 e-105
ref|NP_177742.2| maoC-like dehydratase domain-containing pr... 385 e-105
ref|YP_570240.1| MaoC-like dehydratase [Rhodopseudomonas pa... 385 e-105
ref|NP_773012.1| probable short-chain dehydrogenase [Bradyr... 384 e-104
ref|NP_948531.1| MaoC-like dehydratase:Asparaginase/glutami... 384 e-104
ref|YP_001561226.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-b... 383 e-104
ref|YP_459035.1| oxidoreductase, short chain dehydrogenase/... 382 e-104
ref|NP_771973.1| putative dehydrogenase [Bradyrhizobium jap... 382 e-104
ref|ZP_02299796.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-be... 382 e-104
ref|ZP_01000112.1| MaoC-like dehydratase [Oceanicola batsen... 382 e-104
ref|YP_908150.1| short-chain type dehydrogenase/reductase [... 380 e-103
ref|YP_485968.1| MaoC-like dehydratase [Rhodopseudomonas pa... 380 e-103
ref|YP_884196.1| peroxisomal hydratase-dehydrogenase-epimer... 380 e-103
ref|ZP_01449443.1| oxidoreductase, short chain dehydrogenas... 378 e-103
ref|YP_001632529.1| probable short-chain type dehydrogenase... 378 e-103
ref|ZP_01037658.1| MaoC-like dehydratase [Roseovarius sp. 2... 378 e-103
ref|YP_782438.1| MaoC domain protein dehydratase [Rhodopseu... 378 e-103
ref|NP_946764.1| MaoC-like dehydratase [Rhodopseudomonas pa... 378 e-102
ref|ZP_01012181.1| oxidoreductase, short chain dehydrogenas... 374 e-101
ref|YP_001206284.1| putative dehydratase (MaoC-like) [Brady... 374 e-101
ref|XP_001900411.1| oxidoreductase, short chain dehydrogena... 374 e-101
ref|YP_001238963.1| Putative short-chain dehydrogenase [Bra... 373 e-101
ref|YP_533245.1| MaoC-like dehydratase [Rhodopseudomonas pa... 372 e-101
ref|YP_001133058.1| short-chain dehydrogenase/reductase SDR... 372 e-101
ref|NP_249714.1| probable short-chain dehydrogenase [Pseudo... 371 e-100
ref|YP_792247.1| probable short-chain dehydrogenase [Pseudo... 371 e-100
gb|AAT51173.1| PA1023 [synthetic construct] 371 e-100
ref|YP_984452.1| MaoC domain protein dehydratase [Acidovora... 370 e-100
ref|NP_769597.1| putative short-chain dehydrogenase [Bradyr... 370 e-100
ref|YP_568274.1| MaoC-like dehydratase [Rhodopseudomonas pa... 370 e-100
ref|NP_001063833.1| Os09g0544900 [Oryza sativa (japonica cu... 370 e-100
ref|ZP_02303261.1| 3-alpha,7-alpha,12-alpha-trihydroxy-5-be... 369 e-100
ref|ZP_01520456.1| MaoC-like dehydratase [Comamonas testost... 368 e-100
ref|YP_001204639.1| Putative short-chain dehydrogenase [Bra... 368 e-100
ref|ZP_00964987.1| COG1028: Dehydrogenases with different s... 368 e-100
ref|YP_001629828.1| putative acyl dehydratase [Bordetella p... 368 e-100
ref|YP_641823.1| MaoC-like dehydratase [Mycobacterium sp. M... 368 1e-99
ref|ZP_01016095.1| probable short-chain dehydrogenase [Parv... 367 1e-99
ref|NP_773013.1| hypothetical protein bll6373 [Bradyrhizobi... 367 2e-99
ref|YP_001508000.1| short-chain dehydrogenase/reductase SDR... 367 3e-99
ref|YP_792252.1| hypothetical protein PA14_51160 [Pseudomon... 366 3e-99
ref|NP_249709.1| hypothetical protein PA1018 [Pseudomonas a... 366 3e-99
ref|YP_585946.1| MaoC-like dehydratase [Ralstonia metallidu... 366 5e-99
ref|YP_641564.1| short-chain dehydrogenase/reductase SDR [M... 365 6e-99
ref|YP_002781638.1| putative enoyl-CoA hydratase [Rhodococc... 365 8e-99
ref|ZP_00964979.1| COG2030: Acyl dehydratase [Pseudomonas a... 365 9e-99
ref|NP_962444.1| hypothetical protein MAP3510 [Mycobacteriu... 364 1e-98
ref|ZP_01364378.1| hypothetical protein PaerPA_01001485 [Ps... 364 1e-98
ref|YP_780721.1| short-chain dehydrogenase/reductase SDR [R... 364 1e-98
ref|YP_552038.1| short-chain dehydrogenase/reductase SDR [P... 364 2e-98
ref|YP_726617.1| short chain dehydrogenase [Ralstonia eutro... 364 2e-98
ref|YP_001349713.1| oxidoreductase, short chain dehydrogena... 363 2e-98
ref|YP_001481079.1| short-chain dehydrogenase/reductase SDR... 362 6e-98
ref|YP_704475.1| 2-Enoyl acyl-CoA hydratase [Rhodococcus sp... 361 1e-97
ref|YP_001701360.1| Probable short-chain dehydrogenase/redu... 361 1e-97
ref|YP_889858.1| oxidoreductase, short chain dehydrogenase/... 361 1e-97
ref|YP_487195.1| Short-chain dehydrogenase/reductase SDR [R... 360 2e-97
ref|ZP_02914617.1| 3-oxoacyl-(acyl-carrier-protein) reducta... 360 2e-97
ref|YP_001349719.1| hypothetical protein PSPA7_4366 [Pseudo... 360 2e-97
ref|YP_002768427.1| oxidoreductase [Rhodococcus erythropoli... 360 3e-97
ref|ZP_02300115.1| short-chain dehydrogenase/reductase SDR ... 360 3e-97
ref|YP_367018.1| MaoC-like dehydratase [Burkholderia sp. 38... 359 5e-97
ref|YP_147043.1| 3-ketoacyl-(acyl-carrier-protein) reductas... 359 5e-97
ref|YP_001132788.1| MaoC domain protein dehydratase [Mycoba... 359 6e-97
ref|YP_001125164.1| 3-ketoacyl-(acyl-carrier-protein) reduc... 359 6e-97
ref|NP_947120.1| putative dehydrogenase [Rhodopseudomonas p... 358 7e-97
ref|YP_569014.1| short-chain dehydrogenase/reductase SDR [R... 358 7e-97
ref|YP_890168.1| putative peroxisomal multifunctional enzym... 357 2e-96
ref|YP_298036.1| Short-chain dehydrogenase/reductase SDR [R... 357 2e-96
gb|ABW74860.1| 2-enoyl acyl-CoA hydratase [Rhodococcus eryt... 357 2e-96
ref|YP_705752.1| possible MaoC family dehydratase [Rhodococ... 356 3e-96
ref|NP_771972.1| probable short-chain dehydrogenase [Bradyr... 356 3e-96
ref|XP_001435177.1| hypothetical protein GSPATT00036560001 ... 356 3e-96
ref|ZP_01037648.1| putative short-chain dehydrogenase [Rose... 355 8e-96
ref|YP_641841.1| short chain dehydrogenase [Mycobacterium s... 355 9e-96
ref|YP_955738.1| short-chain dehydrogenase/reductase SDR [M... 355 9e-96
ref|YP_001206283.1| putative short-chain dehydrogenase/redu... 355 9e-96
ref|YP_956015.1| MaoC domain protein dehydratase [Mycobacte... 355 1e-95
ref|NP_243357.1| 3-oxoacyl-(acyl-carrier protein) reductase... 354 1e-95
ref|YP_001240914.1| putative dehydratase [Bradyrhizobium sp... 354 2e-95
ref|ZP_01001040.1| putative dehydrogenase [Oceanicola batse... 354 2e-95
ref|XP_001896267.1| maoC like domain containing protein [Br... 354 2e-95
gb|EEJ96228.1| dehydrogenase of unknown specificity similar... 353 2e-95
ref|ZP_01227959.1| putative short chain dehydrogenase famil... 353 3e-95
ref|ZP_01000038.1| probable short-chain dehydrogenase [Ocea... 352 5e-95
ref|YP_713998.1| putative oxidoreductase [Frankia alni ACN1... 352 5e-95
ref|YP_001658404.1| 3-oxoacyl-[acyl-carrier protein] reduct... 352 5e-95
ref|XP_001763373.1| predicted protein [Physcomitrella paten... 352 6e-95
ref|YP_496504.1| short-chain dehydrogenase/reductase SDR [N... 351 9e-95
ref|YP_001628977.1| probable short-chain type dehydrogenase... 351 1e-94
ref|YP_884321.1| oxidoreductase, short chain dehydrogenase/... 351 1e-94
ref|YP_587648.1| MaoC-like dehydratase [Ralstonia metallidu... 351 1e-94
pdb|1PN4|A Chain A, Crystal Structure Of 2-Enoyl-Coa Hydrat... 351 1e-94
pdb|1PN2|A Chain A, Crystal Structure Analysis Of The Selen... 351 2e-94
ref|YP_552606.1| Short-chain dehydrogenase/reductase SDR [B... 350 2e-94
ref|YP_116668.1| hypothetical protein nfa4620 [Nocardia far... 350 2e-94
emb|CAO91447.1| fabG1 [Microcystis aeruginosa PCC 7806] 350 3e-94
ref|YP_704598.1| short chain dehydrogenase [Rhodococcus sp.... 350 3e-94
ref|YP_001240913.1| putative short-chain dehydrogenase/redu... 350 4e-94
ref|YP_001684866.1| short-chain dehydrogenase/reductase SDR... 349 5e-94
ref|ZP_02299795.1| short-chain dehydrogenase/reductase SDR ... 349 5e-94
ref|XP_001455573.1| hypothetical protein GSPATT00003144001 ... 349 7e-94
ref|ZP_01861660.1| 3-ketoacyl-(acyl-carrier-protein) reduct... 348 7e-94
ref|NP_891300.1| putative (R)-specific enoyl-CoA hydratase ... 348 8e-94
ref|ZP_01726066.1| 3-oxoacyl-(acyl-carrier protein) reducta... 348 8e-94
ref|YP_890225.1| short chain dehydrogenase [Mycobacterium s... 348 9e-94
ref|YP_002764368.1| oxidoreductase [Rhodococcus erythropoli... 348 1e-93
ref|NP_948530.1| putative short-chain dehydrogenase [Rhodop... 348 1e-93
ref|YP_001685634.1| short-chain dehydrogenase/reductase SDR... 348 1e-93
ref|YP_726616.1| putative acyl dehydratase [Ralstonia eutro... 348 1e-93
ref|ZP_02972038.1| 3-oxoacyl-(acyl-carrier-protein) reducta... 348 1e-93
ref|NP_485934.1| 3-ketoacyl-(acyl-carrier-protein) reductas... 348 1e-93
ref|ZP_02942047.1| 3-oxoacyl-(acyl-carrier-protein) reducta... 348 1e-93
ref|ZP_01171570.1| beta-ketoacyl-acyl carrier protein reduc... 348 1e-93
Sequences not found previously or not previously below threshold:
>ref|NP_000405.1| hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
sp|P51659|DHB4_HUMAN Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: 3-hydroxyacyl-CoA
dehydrogenase ;
3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase ]
emb|CAA60643.1| 17beta-hydroxysteroid dehydrogenase [Homo sapiens]
gb|AAD08652.1| 17-beta-hydroxysteroid dehydrogenase IV [Homo sapiens]
gb|AAH03098.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
gb|EAW48911.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Homo
sapiens]
gb|ABM82792.1| hydroxysteroid (17-beta) dehydrogenase 4 [synthetic construct]
gb|ABM85981.1| hydroxysteroid (17-beta) dehydrogenase 4 [synthetic construct]
Length = 736
Score = 1263 bits (3270), Expect = 0.0, Method: Composition-based stats.
Identities = 736/736 (100%), Positives = 736/736 (100%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
Sbjct: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA
Sbjct: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
Sbjct: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI
Sbjct: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
Sbjct: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 721 MLSQKLQMILKDYAKL 736
>ref|XP_001087837.1| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 isoform 1
[Macaca mulatta]
Length = 734
Score = 1226 bits (3173), Expect = 0.0, Method: Composition-based stats.
Identities = 716/736 (97%), Positives = 725/736 (98%), Gaps = 2/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVA+YDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH
Sbjct: 61 EIRRRGGKAVASYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS
Sbjct: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG VSANHTS ATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD
Sbjct: 301 KIDSEG-VSANHTSHATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGSSDFSCLPTFGVIIGQKS+MGGGLAEIPGLSINFAKV+ GE ++ KPL R
Sbjct: 360 LKFVYEGSSDFSCLPTFGVIIGQKSLMGGGLAEIPGLSINFAKVI-GEPSMKAEKPLKRV 418
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV
Sbjct: 419 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 478
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 479 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 538
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
ARR+LQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 539 ARRILQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 598
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDLAPTS TSAKTPSEGGKLQST VFEEIGRRLKD+GPEVVKKVNAVFEWHITKGGNI
Sbjct: 599 AYVDLAPTSDTSAKTPSEGGKLQSTLVFEEIGRRLKDVGPEVVKKVNAVFEWHITKGGNI 658
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI
Sbjct: 659 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 718
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 719 MLSQKLQMILKDYAKL 734
>ref|XP_531860.2| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 2 [Canis familiaris]
Length = 737
Score = 1210 bits (3132), Expect = 0.0, Method: Composition-based stats.
Identities = 643/737 (87%), Positives = 683/737 (92%), Gaps = 1/737 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGS-LAADKVV 59
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+ IDS+GGVS NHTS A STATS FAGAIG K PPFS AYTELE IMYALGVGAS+K+PK
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPK 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
D+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPR
Sbjct: 361 DMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPR 420
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
AG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDKVK
Sbjct: 421 AGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVK 480
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGF
Sbjct: 481 ATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGF 540
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVIS
Sbjct: 541 SARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVIS 600
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
NAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGN
Sbjct: 601 NAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGN 660
Query: 660 IGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGN 719
I AKWTIDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKARGN
Sbjct: 661 IAAKWTIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKARGN 720
Query: 720 IMLSQKLQMILKDYAKL 736
IMLSQKLQMILKDYAKL
Sbjct: 721 IMLSQKLQMILKDYAKL 737
>ref|NP_001075370.1| 17 beta-hydroxysteroid dehydrogenase type 4 [Equus caballus]
gb|AAS77255.1| 17 beta-hydroxysteroid dehydrogenase type 4 [Equus caballus]
Length = 735
Score = 1210 bits (3131), Expect = 0.0, Method: Composition-based stats.
Identities = 637/736 (86%), Positives = 684/736 (92%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRFDGRVVLVTGAG GLGRAYALAF ERGA VVVNDLGGD KGVGK SLAADKVVE
Sbjct: 1 MASQLRFDGRVVLVTGAGGGLGRAYALAFGERGASVVVNDLGGDMKGVGKSSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR RGGKAVA+YDSVE GEK+VKTALDAFGRIDVVVNNAGILRDRSF R+SDEDWDIIH
Sbjct: 61 EIRSRGGKAVASYDSVEAGEKIVKTALDAFGRIDVVVNNAGILRDRSFGRLSDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSASGIYGNFGQANYSAAKLGLLGL+N+LAI
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASGIYGNFGQANYSAAKLGLLGLSNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSR+TQTV PED+VEALKP+YVAPLVLWLCHESCEENG LFEVG
Sbjct: 181 EGKKNNIHCNTIAPQAGSRLTQTVFPEDVVEALKPDYVAPLVLWLCHESCEENGSLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGA+VRQ+N PMTPEAVKANWKKICDF + S PQ+IQESTG II ++S
Sbjct: 241 AGWIGKLRWERTLGALVRQRNQPMTPEAVKANWKKICDFGSVSNPQTIQESTGGIIGLVS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DS GGVS NHTS A STATSGF GAIGQKLP FS YTELEAIMYALGVGASIK+PKD
Sbjct: 301 KMDSNGGVSTNHTSHAASTATSGFVGAIGQKLPSFSSTYTELEAIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI QKS M G LA+IPGLS++FAKVLHGEQYLELYKPLPR
Sbjct: 361 MKFIYEGSSDFSCLPTFGVITAQKS-MLGELAQIPGLSLDFAKVLHGEQYLELYKPLPRT 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCE VVAD+LDKGSGVVI++DVYSYS EL+C+NQFSLFLVGSGGFGGKRTSDK+KV
Sbjct: 420 GKLKCEGVVADILDKGSGVVILLDVYSYSGNELLCYNQFSLFLVGSGGFGGKRTSDKMKV 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDA+LTDTTSLNQAALYRLSGDWNPLHIDPNF+SLAGFDKPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAILTDTTSLNQAALYRLSGDWNPLHIDPNFSSLAGFDKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFAD+DVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVISN
Sbjct: 540 ARHVLQQFADHDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTS AKTPS+GG+LQST VFEEIGRRLKDIG +VVK VNAVFEWHIT+GGN
Sbjct: 600 AYVDLVPTSDMLAKTPSKGGELQSTLVFEEIGRRLKDIGHQVVKTVNAVFEWHITEGGNT 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
A WTIDLK+GSG+VYQGPA+G+ADTT+ LSDE FMEVV GKLDPQKAFFSG+LKA+GNI
Sbjct: 660 AATWTIDLKNGSGEVYQGPARGSADTTLTLSDEHFMEVVQGKLDPQKAFFSGKLKAKGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
M+SQKLQ ILKDYAKL
Sbjct: 720 MVSQKLQKILKDYAKL 735
>gb|AAI22585.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Bos taurus]
Length = 736
Score = 1209 bits (3129), Expect = 0.0, Method: Composition-based stats.
Identities = 631/736 (85%), Positives = 680/736 (92%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRF+GRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDF GVGKGSLAADKVVE
Sbjct: 1 MASTLRFNGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFTGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVEEGEK+VKTALDAFGRID+V+NNAGILRDRSF+RISDEDWD I
Sbjct: 61 EIRRKGGKAVANYDSVEEGEKIVKTALDAFGRIDIVINNAGILRDRSFSRISDEDWDKIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSASGIYGNFGQANY AAKLGLLGL+N LA+
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASGIYGNFGQANYCAAKLGLLGLSNCLAV 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSRMTQ+++PEDLVEALKP+YVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRMTQSILPEDLVEALKPDYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LGA+VRQ+ PMTPEAVKANW KICDF+NA+KP+SIQES GSI+E L+
Sbjct: 241 AGWIGKLRWERSLGALVRQRTQPMTPEAVKANWTKICDFDNATKPKSIQESIGSIVEALN 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KI+S G VSAN TSRATS TS FA AIG K PP +Y EL+ IMYALGVGASIK+PKD
Sbjct: 301 KINSGGEVSANPTSRATSATTSEFARAIGHKFPPLYSSYAELDTIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI+ QKS+M GGLAEIPGLSIN AK+LHGEQYLEL+KP+PRA
Sbjct: 361 MKFIYEGSSDFSCLPTFGVILAQKSIMNGGLAEIPGLSINLAKILHGEQYLELHKPIPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKL+CEA+VAD+LDKGSG+VI++DVY+YS +ELIC+NQFS+F+VGSGG GGKRTSDK K
Sbjct: 421 GKLRCEAIVADILDKGSGLVILVDVYTYSGEELICYNQFSIFVVGSGGSGGKRTSDKAKA 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETG IVISN
Sbjct: 541 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGGIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKTPSEG LQST VFEEIGRRL+ IG EVVKKV AVFEWHITKG N
Sbjct: 601 AYVDLVPASAISAKTPSEGAGLQSTLVFEEIGRRLQGIGEEVVKKVRAVFEWHITKGENT 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPAKG+AD TI LSDEDFMEVVLGKLDPQKA FSGRLKARGNI
Sbjct: 661 AAKWTIDLKTGSGKVYQGPAKGSADVTITLSDEDFMEVVLGKLDPQKAVFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
+LSQKLQMILKDYAKL
Sbjct: 721 LLSQKLQMILKDYAKL 736
>ref|XP_859341.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 5 [Canis familiaris]
Length = 739
Score = 1204 bits (3116), Expect = 0.0, Method: Composition-based stats.
Identities = 641/739 (86%), Positives = 681/739 (92%), Gaps = 3/739 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGS-LAADKVV 59
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVSANHTSRATSTATSGFA--GAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
+ IDS+GGVS NHTS A STATS GAIG K PPFS AYTELE IMYALGVGAS+K+
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEADMAGAIGHKFPPFSSAYTELETIMYALGVGASVKE 360
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPL 417
PKD+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPL
Sbjct: 361 PKDMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPL 420
Query: 418 PRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDK 477
PRAG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDK
Sbjct: 421 PRAGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDK 480
Query: 478 VKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTF 537
VK VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTF
Sbjct: 481 VKATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTF 540
Query: 538 GFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIV 597
GFSAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIV
Sbjct: 541 GFSARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIV 600
Query: 598 ISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKG 657
ISNAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKG
Sbjct: 601 ISNAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKG 660
Query: 658 GNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKAR 717
GNI AKWTIDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKAR
Sbjct: 661 GNIAAKWTIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKAR 720
Query: 718 GNIMLSQKLQMILKDYAKL 736
GNIMLSQKLQMILKDYAKL
Sbjct: 721 GNIMLSQKLQMILKDYAKL 739
>ref|NP_001007810.1| hydroxysteroid (17-beta) dehydrogenase 4 [Bos taurus]
emb|CAH17988.1| multifunctional protein 2 [Bos taurus]
Length = 736
Score = 1204 bits (3115), Expect = 0.0, Method: Composition-based stats.
Identities = 628/736 (85%), Positives = 678/736 (92%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S LRF+GRVVLVTGAG GLGRAYALAFAERGA VVVNDL GDF GVGKGSL+ADKVVE
Sbjct: 1 MASTLRFNGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLRGDFTGVGKGSLSADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVEEGEK+VKTALDAFGRID+V+NNAGILRDRSF+RISDEDWD I
Sbjct: 61 EIRRKGGKAVANYDSVEEGEKIVKTALDAFGRIDIVINNAGILRDRSFSRISDEDWDKIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQK+GRIIMTSSAS IYGNFGQANY AAKLGLLGL+N LA+
Sbjct: 121 RVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASRIYGNFGQANYCAAKLGLLGLSNCLAV 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSRMTQ+++PEDLVEALKP+YVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRMTQSILPEDLVEALKPDYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LGA+VRQ+ PMTPEAVKANW KICDF+NA+KP+SIQES GSI+E L+
Sbjct: 241 AGWIGKLRWERSLGALVRQRTQPMTPEAVKANWTKICDFDNATKPKSIQESIGSIVEALN 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KI+S G VSAN TSRATS TS FA AIG K PP +Y EL+ IMYALGVGASIK+PKD
Sbjct: 301 KINSGGEVSANPTSRATSATTSEFARAIGHKFPPLYSSYAELDTIMYALGVGASIKEPKD 360
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
+KFIYEGSSDFSCLPTFGVI+ QKS+M GGLAEIPGLSIN AK+LHGEQYLEL+KP+PRA
Sbjct: 361 MKFIYEGSSDFSCLPTFGVILAQKSIMNGGLAEIPGLSINLAKILHGEQYLELHKPIPRA 420
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKL+CEA+VAD+LDKGSG+VI++DVY+YS +ELIC+NQFS+F+VGSGG GGKRTSDK K
Sbjct: 421 GKLRCEAIVADILDKGSGLVILVDVYTYSGEELICYNQFSIFVVGSGGSGGKRTSDKAKA 480
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS
Sbjct: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETG IVISN
Sbjct: 541 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGGIVISN 600
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKTPSEG LQST VFEEIGRRL+ IG EVVKKV AVFEWHITKG N
Sbjct: 601 AYVDLVPASAISAKTPSEGAGLQSTLVFEEIGRRLQGIGEEVVKKVRAVFEWHITKGENT 660
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPAKG+AD TI LSDEDFMEVVLGKLDPQKA FSGRLKARGNI
Sbjct: 661 AAKWTIDLKTGSGKVYQGPAKGSADVTITLSDEDFMEVVLGKLDPQKAVFSGRLKARGNI 720
Query: 721 MLSQKLQMILKDYAKL 736
+LSQKLQMILKDYAKL
Sbjct: 721 LLSQKLQMILKDYAKL 736
>ref|NP_077368.2| hydroxysteroid (17-beta) dehydrogenase 4 [Rattus norvegicus]
sp|P97852|DHB4_RAT Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: 3-hydroxyacyl-CoA
dehydrogenase ;
3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase ]
gb|AAB49519.1| 17 beta-hydroxysteroid dehydrogenase type IV; HSD IV [Rattus sp.]
Length = 735
Score = 1200 bits (3107), Expect = 0.0, Method: Composition-based stats.
Identities = 643/736 (87%), Positives = 690/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG +S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>ref|XP_859306.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 4 [Canis familiaris]
Length = 753
Score = 1200 bits (3106), Expect = 0.0, Method: Composition-based stats.
Identities = 642/753 (85%), Positives = 683/753 (90%), Gaps = 17/753 (2%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGS-LAADKVV 59
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGLGKGSFAAADKVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EEIR +GGKAVANYDSVE GEK+V+TAL+AFGRIDVVVNNAGILRD SF RISDEDWDII
Sbjct: 61 EEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRIDVVVNNAGILRDSSFGRISDEDWDII 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
HRVHLRGSFQVTRAAW HMKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LA
Sbjct: 121 HRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG+ SNIHCNTIAP AGSRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEV
Sbjct: 181 IEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEV 240
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
G GWIGKLRWERTLGAIVRQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V+
Sbjct: 241 GGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVV 300
Query: 300 SKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+ IDS+GGVS NHTS A STATS FAGAIG K PPFS AYTELE IMYALGVGAS+K+PK
Sbjct: 301 NTIDSDGGVSTNHTSHAASTATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPK 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
D+KFIYEGS+DFSCLPTFGVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPR
Sbjct: 361 DMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPR 420
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
AG L+CEAVVADVLDKGSG VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDKVK
Sbjct: 421 AGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVK 480
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
VA+PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGF
Sbjct: 481 ATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGF 540
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VLQ+FADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVIS
Sbjct: 541 SARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVIS 600
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
NAYVDL PTS TSA+TPSEGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGN
Sbjct: 601 NAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGN 660
Query: 660 IGAKWT----------------IDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKL 703
I AKW+ IDLKSG GKVYQGPAKG AD T LSDEDFM+VVLGKL
Sbjct: 661 IAAKWSNRVISFSISLFLLLTAIDLKSGFGKVYQGPAKGPADATFTLSDEDFMDVVLGKL 720
Query: 704 DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 721 DPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 753
>ref|XP_517892.2| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 [Pan
troglodytes]
Length = 712
Score = 1197 bits (3099), Expect = 0.0, Method: Composition-based stats.
Identities = 695/701 (99%), Positives = 697/701 (99%)
Query: 36 VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDV 95
V +NDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDV
Sbjct: 12 VSMNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDV 71
Query: 96 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 155
VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI
Sbjct: 72 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 131
Query: 156 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKP 215
YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKP
Sbjct: 132 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKP 191
Query: 216 EYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKK 275
EYVAPLVLWLCH+SCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKK
Sbjct: 192 EYVAPLVLWLCHDSCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKK 251
Query: 276 ICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPF 335
ICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPF
Sbjct: 252 ICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPF 311
Query: 336 SYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIP 395
SYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIP
Sbjct: 312 SYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIP 371
Query: 396 GLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELIC 455
GLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELIC
Sbjct: 372 GLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELIC 431
Query: 456 HNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLH 515
HNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLH
Sbjct: 432 HNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLH 491
Query: 516 IDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQT 575
IDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQT
Sbjct: 492 IDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQT 551
Query: 576 EMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRL 635
EMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTS TSAKTPSEG KLQST VFEEIGRRL
Sbjct: 552 EMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSDTSAKTPSEGEKLQSTLVFEEIGRRL 611
Query: 636 KDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDF 695
KDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDF
Sbjct: 612 KDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDF 671
Query: 696 MEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
MEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 672 MEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 712
>gb|AAB09724.1| peroxisomal multifunctional enzyme type II
Length = 735
Score = 1193 bits (3088), Expect = 0.0, Method: Composition-based stats.
Identities = 640/736 (86%), Positives = 687/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDS E GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSGEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIY NFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYSNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG +S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+ GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLTSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPDRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>ref|NP_032318.2| hydroxysteroid (17-beta) dehydrogenase 4 [Mus musculus]
sp|P51660|DHB4_MOUSE Peroxisomal multifunctional enzyme type 2 (MFE-2) (D-bifunctional
protein) (DBP) (17-beta-hydroxysteroid dehydrogenase 4)
(17-beta-HSD 4) [Includes: 3-hydroxyacyl-CoA
dehydrogenase ;
3-alpha,7-alpha,
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA
hydratase ]
dbj|BAB23627.1| unnamed protein product [Mus musculus]
gb|AAH22175.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Mus musculus]
dbj|BAC40317.1| unnamed protein product [Mus musculus]
dbj|BAE40862.1| unnamed protein product [Mus musculus]
dbj|BAE39029.1| unnamed protein product [Mus musculus]
dbj|BAE39222.1| unnamed protein product [Mus musculus]
gb|EDL09936.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_d [Mus
musculus]
Length = 735
Score = 1192 bits (3085), Expect = 0.0, Method: Composition-based stats.
Identities = 635/736 (86%), Positives = 687/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG +S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>dbj|BAE36514.1| unnamed protein product [Mus musculus]
Length = 735
Score = 1190 bits (3080), Expect = 0.0, Method: Composition-based stats.
Identities = 635/736 (86%), Positives = 686/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG +S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTHTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>gb|AAH72472.1| Hsd17b4 protein [Rattus norvegicus]
Length = 751
Score = 1189 bits (3076), Expect = 0.0, Method: Composition-based stats.
Identities = 642/752 (85%), Positives = 689/752 (91%), Gaps = 17/752 (2%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG +S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKW----------------TIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLD 704
AKW IDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+
Sbjct: 660 AAKWMELTISFSVSSLLPANAIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLN 719
Query: 705 PQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
PQ AFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 720 PQNAFFSGRLKARGNIMLSQKLQMILKDYAKL 751
>dbj|BAE27744.1| unnamed protein product [Mus musculus]
Length = 735
Score = 1187 bits (3072), Expect = 0.0, Method: Composition-based stats.
Identities = 634/736 (86%), Positives = 686/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG +S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSG WNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGGWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>emb|CAA62015.1| 17beta-hydroxysteroid dehydrogenase IV [Mus musculus]
Length = 735
Score = 1184 bits (3064), Expect = 0.0, Method: Composition-based stats.
Identities = 633/736 (86%), Positives = 685/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTG G GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGPGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDIIH
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL N+LAI
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I+EVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+DSEG +S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+K+PKD
Sbjct: 301 KVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYKPL R+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLLRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD+VISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHITKGG +
Sbjct: 600 AYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLKARGNI
Sbjct: 660 AAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYAKL
Sbjct: 720 MLSQKLQMILKDYAKL 735
>emb|CAA64427.1| multifunctional protein 2 [Rattus norvegicus]
Length = 734
Score = 1182 bits (3060), Expect = 0.0, Method: Composition-based stats.
Identities = 635/734 (86%), Positives = 683/734 (93%), Gaps = 1/734 (0%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
SPLRFDGRV LVTGAG GLGRAY LAFAERGALVVVNDLGGDFKGVGKGS AADKVVEEI
Sbjct: 2 SPLRFDGRVGLVTGAGGGLGRAYGLAFAERGALVVVNDLGGDFKGVGKGSSAADKVVEEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
RRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRD SF+RISDEDWDII RV
Sbjct: 62 RRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDPSFSRISDEDWDIIQRV 121
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
HLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L IEG
Sbjct: 122 HLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVIEG 181
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 242
RK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG
Sbjct: 182 RKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 241
Query: 243 WIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKI 302
WIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NAS+P+SIQESTG IIEVL KI
Sbjct: 242 WIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASEPKSIQESTGGIIEVLHKI 301
Query: 303 DSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLK 362
DSEG +S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKDLK
Sbjct: 302 DSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDLK 360
Query: 363 FIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGK 422
F+YEGS DFSCLPT GVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+G+
Sbjct: 361 FVYEGSPDFSCLPTIGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRSGE 420
Query: 423 LKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAV 482
LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K AV
Sbjct: 421 LKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAAV 480
Query: 483 AIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSAR 542
A+P+RPPDAVL DTTS+NQAALYRLSGD NPLHIDP+FA +AGF+KPILHGLCTFGFSAR
Sbjct: 481 AVPSRPPDAVLRDTTSVNQAALYRLSGDSNPLHIDPSFAGIAGFEKPILHGLCTFGFSAR 540
Query: 543 RVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY 602
VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY
Sbjct: 541 HVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAY 600
Query: 603 VDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGA 662
VDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+ A
Sbjct: 601 VDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVAA 660
Query: 663 KWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIML 722
KWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ AFFSGRLKARGNIML
Sbjct: 661 KWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQNAFFSGRLKARGNIML 720
Query: 723 SQKLQMILKDYAKL 736
SQKLQMILKDYAKL
Sbjct: 721 SQKLQMILKDYAKL 734
>emb|CAA73945.1| mutifunctional protein2 [Cavia porcellus]
Length = 735
Score = 1175 bits (3042), Expect = 0.0, Method: Composition-based stats.
Identities = 620/736 (84%), Positives = 688/736 (93%), Gaps = 1/736 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MGSPLRFDGRVVLVTGAG GLGRAYALAFAERGA V+V+DLGGDFKGVGKGSLAADKVVE
Sbjct: 1 MGSPLRFDGRVVLVTGAGGGLGRAYALAFAERGASVIVDDLGGDFKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GG+AVANYDSVE GEK+VK ALDAFGRIDVVVNNAGIL RSF+RISDEDWDI+H
Sbjct: 61 EIRRKGGRAVANYDSVEAGEKIVKAALDAFGRIDVVVNNAGILTHRSFSRISDEDWDIVH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHL GSFQVTRAAW HMKKQ YGRIIMT+S++GIYGNFGQANYSAAKLGLLGL+N++AI
Sbjct: 121 RVHLWGSFQVTRAAWNHMKKQNYGRIIMTTSSAGIYGNFGQANYSAAKLGLLGLSNTIAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNTIAP AGSR+TQTVMP+DLV+ALKPEYVAPLVLWLCH+SCEENGGLFEVG
Sbjct: 181 EGKKNNIHCNTIAPTAGSRLTQTVMPDDLVQALKPEYVAPLVLWLCHDSCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR+KN P+TPE VKANWKKICDF+NASKPQSIQESTG ++E+L
Sbjct: 241 AGWIGKLRWERTLGAIVRRKNEPVTPETVKANWKKICDFDNASKPQSIQESTGGMVEILH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSE VS N TS ATSTA+ G+A AIG KLP FS +YTEL+ IMYALGVGAS+KDPK+
Sbjct: 301 KIDSEE-VSTNPTSHATSTASPGYASAIGYKLPSFSPSYTELDCIMYALGVGASVKDPKN 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEGS DFSCLPTFGVI+ QKS+ GGGLA++ GLSINFAKVLHGEQYL++YKP PRA
Sbjct: 360 LRFLYEGSPDFSCLPTFGVIVAQKSVFGGGLADVSGLSINFAKVLHGEQYLQIYKPFPRA 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
GKLKCEAV+AD+LDKGSG+VI++DVY+YS +ELIC+NQFS+F+VGSGGFGGKRTS+K+KV
Sbjct: 420 GKLKCEAVIADILDKGSGLVIVLDVYAYSGEELICYNQFSVFVVGSGGFGGKRTSEKLKV 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVAIP+RPPDAV+TD TSL+QAALYRLSGDWNPLHIDPNFAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAIPSRPPDAVITDNTSLDQAALYRLSGDWNPLHIDPNFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVS+FKAIK RFAKPVYPGQTL+TEMWKEGNRIHFQTK+ ETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSKFKAIKVRFAKPVYPGQTLKTEMWKEGNRIHFQTKILETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL P S SAKT EGG+LQST VFEEI RRLKDIG + VKKVNAVFEWHITKGGN
Sbjct: 600 AYVDLVPPSDLSAKTHPEGGELQSTRVFEEINRRLKDIGHKEVKKVNAVFEWHITKGGNT 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
AKWTIDLK+GSGKVYQGPA+G+ADT+I++SDEDFMEVVLGKLDPQKAFFSGRLKA+GNI
Sbjct: 660 AAKWTIDLKNGSGKVYQGPAEGSADTSILISDEDFMEVVLGKLDPQKAFFSGRLKAKGNI 719
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKLQMILKDYA L
Sbjct: 720 MLSQKLQMILKDYANL 735
>ref|NP_999471.1| hydroxysteroid (17-beta) dehydrogenase 4 [Sus scrofa]
emb|CAA55037.1| 17beta-estradiol dehydrogenase [Sus scrofa]
Length = 737
Score = 1174 bits (3038), Expect = 0.0, Method: Composition-based stats.
Identities = 623/737 (84%), Positives = 673/737 (91%), Gaps = 1/737 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M S L F GRVVLVTGAG GLGR YALAFAERGA VVVNDLGGD KGVGKGSLAADKVVE
Sbjct: 1 MASMLNFYGRVVLVTGAGGGLGRTYALAFAERGASVVVNDLGGDMKGVGKGSLAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRR+GGKAVANYDSVE GEK+VK ALDAFGRIDVVVNNAGILRDRSF+RISDEDWD+I
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKIVKAALDAFGRIDVVVNNAGILRDRSFSRISDEDWDMIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW+HMKKQ +GRIIMTSSA+GIYGNFGQANYSAAKLGLLGL+NSLA+
Sbjct: 121 RVHLRGSFMVTRAAWDHMKKQNFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLSNSLAV 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K+NIHCNT+AP AGSRMTQ +PEDL+EALKPEYVAPLVLWLCHESCEENG +FEVG
Sbjct: 181 EGKKNNIHCNTVAPVAGSRMTQGFLPEDLIEALKPEYVAPLVLWLCHESCEENGSVFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGA+VRQKN PMTPEAVKANW KICDF+NA+KPQ IQ+S ++IE LS
Sbjct: 241 AGWIGKLRWERTLGALVRQKNQPMTPEAVKANWTKICDFDNATKPQRIQDSVSTVIEALS 300
Query: 301 KIDS-EGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
KIDS +GG+SAN+ S ATS A SG A+G K PPFS +YTE++ IMYA GVGASIK+PK
Sbjct: 301 KIDSSDGGISANNLSHATSAAPSGLVEAVGYKFPPFSSSYTEVDTIMYAFGVGASIKEPK 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
DLKFIYEG+SDFSCLPTFGVI+ QKS+ GGGLAEIPGLS+NF KVLHGE YLELYKPLP
Sbjct: 361 DLKFIYEGNSDFSCLPTFGVILAQKSLGGGGLAEIPGLSVNFTKVLHGEHYLELYKPLPN 420
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
AG LKCEAVVADVLDK SG+VI++DVYSYS KELIC+NQFS+F++GSGGFGGKRTSDK K
Sbjct: 421 AGDLKCEAVVADVLDKRSGLVILIDVYSYSGKELICYNQFSVFVMGSGGFGGKRTSDKDK 480
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
VAVAIPNRPPDA+LTDTTSLNQAALYRLSGDWNPLHIDP+FASLAGFD+PILHGLCTFGF
Sbjct: 481 VAVAIPNRPPDAILTDTTSLNQAALYRLSGDWNPLHIDPDFASLAGFDRPILHGLCTFGF 540
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VLQQ+AD DV RFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGD VIS
Sbjct: 541 SARHVLQQYADRDVLRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDTVIS 600
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
NAYVDL PTS T AK PSEGG LQS VFEEIGRRL+DIG E+VKKVNAVFEWHITKG
Sbjct: 601 NAYVDLVPTSDTLAKIPSEGGDLQSNLVFEEIGRRLQDIGQEMVKKVNAVFEWHITKGEK 660
Query: 660 IGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGN 719
I AKWTIDLK+G+GKVYQGPAKG+AD T ILSDE FMEVVLGKLDPQKAFFSGRLKARGN
Sbjct: 661 IAAKWTIDLKNGAGKVYQGPAKGSADATFILSDEVFMEVVLGKLDPQKAFFSGRLKARGN 720
Query: 720 IMLSQKLQMILKDYAKL 736
IMLSQKLQMILKDYAK+
Sbjct: 721 IMLSQKLQMILKDYAKI 737
>gb|EDL09934.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Mus
musculus]
Length = 733
Score = 1164 bits (3012), Expect = 0.0, Method: Composition-based stats.
Identities = 628/741 (84%), Positives = 680/741 (91%), Gaps = 13/741 (1%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALV+VNDLGGDFKG+GKGS AADKVV
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVA 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAG-----ILRDRSFARISDED 115
EIRR+GGKAVANYDSVE GEK+VKTALD FGRI G ILRDRSF+RISDED
Sbjct: 61 EIRRKGGKAVANYDSVEAGEKLVKTALDTFGRI-------GDQYFRILRDRSFSRISDED 113
Query: 116 WDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLA 175
WDIIHRVHLRGSFQVTRAAW+HMKKQ YGRI+MTSSASGIYGNFGQANYSAAKLG+LGL
Sbjct: 114 WDIIHRVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLC 173
Query: 176 NSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGG 235
N+LAIEGRK+NIHCNTIAPNAGSRMT+TV+PEDLVEALKPEYVAPLVLWLCHESCEENGG
Sbjct: 174 NTLAIEGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGG 233
Query: 236 LFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSI 295
LFEVGAGWIGKLRWERTLGAIVR++N PMTPEAV+ NW+KICDF NASKPQ+IQESTG I
Sbjct: 234 LFEVGAGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGI 293
Query: 296 IEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASI 355
+EVL K+DSEG +S N TS A ATSGF GA+G KLP FS +YTEL++IMYALGVGAS+
Sbjct: 294 VEVLHKVDSEG-ISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASV 352
Query: 356 KDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYK 415
K+PKDLKF+YEGS+DFSCLPTFGVI+ QKSMM GGLAE+PGLS NFAK LHGEQYLELYK
Sbjct: 353 KNPKDLKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYK 412
Query: 416 PLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTS 475
PLPR+G+LKCEAV+AD+LDKGSGVVI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS
Sbjct: 413 PLPRSGELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTS 472
Query: 476 DKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLC 535
+K+K AVA+PNRPPDAVL D TSLNQAALYRLSGDWNPLHIDP+FAS+AGF+KPILHGLC
Sbjct: 473 EKLKAAVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLC 532
Query: 536 TFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGD 595
TFGFSAR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKV ETGD
Sbjct: 533 TFGFSARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGD 592
Query: 596 IVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHIT 655
+VISNAYVDL P SG S +TPSEGG+LQS VF EIGRRLK +G EVVKK NAVFEWHIT
Sbjct: 593 VVISNAYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHIT 652
Query: 656 KGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLK 715
KGG + AKWTIDLKSGSG+VYQGPAKG+AD TII+SDEDFMEVV GKLDPQKAFFSGRLK
Sbjct: 653 KGGTVAAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLK 712
Query: 716 ARGNIMLSQKLQMILKDYAKL 736
ARGNIMLSQKLQMILKDYAKL
Sbjct: 713 ARGNIMLSQKLQMILKDYAKL 733
>dbj|BAF74749.1| hydroxysteroid (17-beta) dehydrogenase 4 [Fundulus heteroclitus]
Length = 738
Score = 1153 bits (2983), Expect = 0.0, Method: Composition-based stats.
Identities = 517/737 (70%), Positives = 608/737 (82%), Gaps = 4/737 (0%)
Query: 4 PLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIR 63
L F+GRVVLVTGAG GLG+ YALAFA RGA VVVNDLG D KG G+ S AADKVVEEIR
Sbjct: 2 SLSFEGRVVLVTGAGGGLGKEYALAFASRGASVVVNDLGVDTKGGGRSSAAADKVVEEIR 61
Query: 64 RRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVH 123
+GGKAVANYDSVE+GEK++++ALDAFGRID+VVNNAGILRDRSFAR SD DWD+IHR+H
Sbjct: 62 AKGGKAVANYDSVEDGEKLIQSALDAFGRIDIVVNNAGILRDRSFARTSDLDWDLIHRIH 121
Query: 124 LRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGR 183
LRGSF VTRAAW HMK QK+GRIIMT+SA+GIYGNFGQANYSAAKLGLLGLAN+LAIEG
Sbjct: 122 LRGSFLVTRAAWNHMKNQKFGRIIMTASAAGIYGNFGQANYSAAKLGLLGLANTLAIEGH 181
Query: 184 KSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGW 243
K NIHCNTIAP AGSR+T+TVMP DLV +LKPEYVAPLVLWLCHE C+ENGGLFEVGAGW
Sbjct: 182 KYNIHCNTIAPVAGSRLTETVMPPDLVASLKPEYVAPLVLWLCHEQCKENGGLFEVGAGW 241
Query: 244 IGKLRWERTLGAIVRQKNHPMTPEAV-KANWKKICDFENASKPQSIQESTGSIIEVLSKI 302
IGKLRWERT G VRQ+N PMTPE V +W ICDFENA+KP ++QES S++ VLS++
Sbjct: 242 IGKLRWERTQGRTVRQRNKPMTPEGVPGTSWDAICDFENATKPANVQESLHSVVSVLSQV 301
Query: 303 DSEGGVSANHTSRATSTAT---SGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+S+G V AN T+ A S A+ A A+GQKLP S+++T + I+YALGVG S KDP
Sbjct: 302 ESDGDVGANPTAAAASGASGSGINPAEAVGQKLPTSSFSFTPTQCILYALGVGMSTKDPD 361
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
+L+F+YEG DFSCLPTFGVI Q + MGGGL+ +PGLSI+F +VLHGEQYLELYKPLP
Sbjct: 362 NLRFLYEGHQDFSCLPTFGVIPSQAATMGGGLSSVPGLSIDFTQVLHGEQYLELYKPLPT 421
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
+G L E VADVLDKGSG VI++DV SYS EL+C+NQFS+F+VG+ FGGKR+SDK K
Sbjct: 422 SGTLTSETTVADVLDKGSGAVILLDVNSYSGDELVCYNQFSVFVVGARRFGGKRSSDKAK 481
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
+ P R PDAV+ ++T+ +QAALYRLSGDWNPLHIDP+FA++ GF PILHGLC+FGF
Sbjct: 482 APLPPPKRAPDAVVIESTTRDQAALYRLSGDWNPLHIDPSFAAMGGFSAPILHGLCSFGF 541
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
+AR VLQ+FA+ND S+FKAIK RFAKPV+PGQ+LQTEMWKEG+RIH Q KV+ETGD+ ++
Sbjct: 542 AARHVLQRFANNDPSKFKAIKVRFAKPVFPGQSLQTEMWKEGSRIHIQCKVKETGDVALA 601
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
YVDL TS S +T +GG LQS VF EIGRR+ ++G E+VKKVNAVF W ITK G
Sbjct: 602 GGYVDLHGTSEASPETLPQGGGLQSELVFAEIGRRVTELGSELVKKVNAVFGWEITKDGK 661
Query: 660 IGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGN 719
A WTIDLK+GSG + +GP G AD T +SDEDFM+VV GKL PQKAFFSG+LK RGN
Sbjct: 662 KAADWTIDLKNGSGSLLKGPYGGKADVTFTVSDEDFMQVVTGKLPPQKAFFSGKLKVRGN 721
Query: 720 IMLSQKLQMILKDYAKL 736
IMLSQKL++ILKDYAKL
Sbjct: 722 IMLSQKLEVILKDYAKL 738
>ref|NP_001027490.1| hypothetical protein LOC613082 [Xenopus tropicalis]
gb|AAH96498.1| Hypothetical protein mgc108050 [Xenopus tropicalis]
Length = 740
Score = 1150 bits (2975), Expect = 0.0, Method: Composition-based stats.
Identities = 524/738 (71%), Positives = 622/738 (84%), Gaps = 3/738 (0%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
LRFDGRVVLVTGAG GLGR YALAFAERGA V+VNDLGGD KG GK S AADKVVEE
Sbjct: 3 SQALRFDGRVVLVTGAGGGLGRTYALAFAERGASVIVNDLGGDIKGEGKSSSAADKVVEE 62
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR +GGKAVANYDSVE GEK+V+TALDAFGRID+VVNNAGILRDRSFARISD DWDIIHR
Sbjct: 63 IRAKGGKAVANYDSVEAGEKLVQTALDAFGRIDIVVNNAGILRDRSFARISDADWDIIHR 122
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHL+G+F +TRAAW HMK QK+GRIIMTSSA+GIYGNFGQANYSAAKLGL+GL+N+LAIE
Sbjct: 123 VHLKGAFLITRAAWNHMKNQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLVGLSNTLAIE 182
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K NIH N IAP AGSR+TQTVMP+DL++ALKPEYV PLVLWLCHESC+E G LFEVGA
Sbjct: 183 GTKYNIHSNCIAPTAGSRLTQTVMPQDLLDALKPEYVTPLVLWLCHESCQETGSLFEVGA 242
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
GW+GKLRWER+LGAI+RQKN PMTPEAV+ W KI DF+NA KPQ+IQ+S + +VLS+
Sbjct: 243 GWVGKLRWERSLGAIIRQKNRPMTPEAVRDEWAKISDFDNADKPQTIQDSINPLYQVLSQ 302
Query: 302 IDSEGGVSANHTSRATSTATSGFA--GAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
DSE G+S N TS+ TS +TS AIGQKLP +Y Y+ LE I+YALGVG S +DP
Sbjct: 303 TDSEKGMSMNPTSQGTSLSTSSIDPVKAIGQKLPLTTYTYSHLEPILYALGVGMSTRDPD 362
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
LKF+YEGS DFSCLP+FGVI+ Q + M GGLA +PGL+I+F +VLHGEQYLE+YKPLP
Sbjct: 363 HLKFLYEGSEDFSCLPSFGVIVSQAAFMSGGLASVPGLNIDFTRVLHGEQYLEIYKPLPT 422
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
+G++ A VAD++DKGSG +I++DV++Y +L+C+NQFS+F+VG+GGFGGKR+S K K
Sbjct: 423 SGEMTSHATVADIMDKGSGAIILLDVHTYHGVDLVCYNQFSVFVVGAGGFGGKRSSSKAK 482
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
P+RPPD V+TD T+ +QAALYRLSGDWNPLHIDP+FA++ GF+KPILHGLC+FGF
Sbjct: 483 ATANPPSRPPDVVVTDATNADQAALYRLSGDWNPLHIDPSFAAMGGFEKPILHGLCSFGF 542
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VL+ FA+NDV++FKAIK RFAKPV PGQTLQTEMWKEGNRI QTKV++TG+I I+
Sbjct: 543 SARHVLKHFANNDVTKFKAIKVRFAKPVLPGQTLQTEMWKEGNRIFLQTKVKDTGEIAIA 602
Query: 600 NAYVDLAPTSGT-SAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGG 658
AYVDL T +K P + G LQS VF+EI RR+KD+G ++VKKVNAVF+W ITK G
Sbjct: 603 GAYVDLTSTENNLESKGPVQDGGLQSDLVFDEISRRVKDLGEQLVKKVNAVFQWDITKDG 662
Query: 659 NIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARG 718
++WTIDLKSGSG+VY+G A+G ADT+ LSDEDFME+VLG L+PQKAFF+G+LK +G
Sbjct: 663 KPASQWTIDLKSGSGEVYRGKARGRADTSFTLSDEDFMELVLGNLNPQKAFFAGKLKVKG 722
Query: 719 NIMLSQKLQMILKDYAKL 736
NIMLSQKL+MILKDYAKL
Sbjct: 723 NIMLSQKLEMILKDYAKL 740
>gb|EDM14436.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_b [Rattus
norvegicus]
Length = 708
Score = 1141 bits (2952), Expect = 0.0, Method: Composition-based stats.
Identities = 614/707 (86%), Positives = 661/707 (93%), Gaps = 1/707 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M SPLRFDGRVVLVTGAG GLGRAYALAFAERGALVVVNDLGGDFKGVGKGS AADKVVE
Sbjct: 1 MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSSAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIRRRGGKAVANYDSVE GEK+VKTALD FGRIDVVVNNAGILRDRSF+RISDEDWDII
Sbjct: 61 EIRRRGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSFQVTRAAW+HMKKQ YGRIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L I
Sbjct: 121 RVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK+NIHCNTIAPNAGSRMT+TVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG
Sbjct: 181 EGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWERTLGAIVR++N PMTPEAV+ NW KICDF NASKP+SIQESTG IIEVL
Sbjct: 241 AGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLH 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
KIDSEG +S NHT + S SGFAG +G KLP FS +YTEL+ IMYALGVGAS+K+PKD
Sbjct: 301 KIDSEG-ISQNHTGQVASADASGFAGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKD 359
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YEGS+DFSCLPTFGVI+ QKS+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+
Sbjct: 360 LKFVYEGSADFSCLPTFGVIVAQKSLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRS 419
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G+LKCEAV+AD+LDKGSG+VI+MDVYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K
Sbjct: 420 GELKCEAVIADILDKGSGIVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKA 479
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
AVA+P+RPPDAVL DTTSLNQAALYRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFS
Sbjct: 480 AVAVPSRPPDAVLRDTTSLNQAALYRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFS 539
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VLQQFADNDVSRFKAIK RFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN
Sbjct: 540 ARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 599
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AYVDL PTSG SA+TPSEGG LQS VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+
Sbjct: 600 AYVDLVPTSGVSAQTPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNV 659
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQK 707
AKWTIDLK+GSG+VYQGPAKG+ADTTI +SDEDFMEVVLGKL+PQ
Sbjct: 660 AAKWTIDLKNGSGEVYQGPAKGSADTTITISDEDFMEVVLGKLNPQN 706
>ref|NP_990274.1| hydroxysteroid (17-beta) dehydrogenase 4 [Gallus gallus]
gb|AAC60249.1| 17-beta-hydroxysteroid dehydrogenase type IV [Gallus gallus]
Length = 735
Score = 1135 bits (2937), Expect = 0.0, Method: Composition-based stats.
Identities = 528/738 (71%), Positives = 619/738 (83%), Gaps = 5/738 (0%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M + LRFDGRVVLVTGAG GLGRAYALAFAERGA VVVNDLGGDFKG GK S AADKVV
Sbjct: 1 MAAGLRFDGRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDFKGYGKSSSAADKVVS 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAV NYDSVE+GEK+VK+AL+AFGRID+V+NNAGILRDRSF RISDEDWDIIH
Sbjct: 61 EIRANGGKAVPNYDSVEDGEKLVKSALEAFGRIDIVINNAGILRDRSFVRISDEDWDIIH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
R+HLRGSF VTRAAW HMK QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGL+N++AI
Sbjct: 121 RIHLRGSFLVTRAAWNHMKNQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLSNTIAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EGRK NIHCNTIAP AGSR+TQTVMP+DL++A KPEYVAPLVLWLCHE+C ENG LFEVG
Sbjct: 181 EGRKYNIHCNTIAPTAGSRLTQTVMPQDLIDAFKPEYVAPLVLWLCHETCMENGSLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LGAIVR K+ PMTPEAV+ W+K+CDF NASKP+SIQES + + LS
Sbjct: 241 AGWIGKLRWERSLGAIVRGKDQPMTPEAVRDKWEKVCDFNNASKPRSIQESISVLNDALS 300
Query: 301 KIDSEGGVSANHT-SRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+I+S+G +S N T SR+ ++ +G++L Y YT LE I+YALGVG S KDP
Sbjct: 301 QIESQGSISMNSTNSRSVVSSAVDTTSLVGRELTTKVYKYTHLEPILYALGVGMSTKDPD 360
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
LKF++EGS +F CLPTFGVI Q SM G IPGL ++ AK+LHGEQYLELYKPLP
Sbjct: 361 HLKFLFEGSEEFCCLPTFGVIPAQTSMFDGVP-SIPGLDMDLAKMLHGEQYLELYKPLPT 419
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
+G+L+ + +AD+LDKGSG V+++DV +Y K+L+C+NQFSLF VG+GGFGGKRTS+K K
Sbjct: 420 SGELRSVSTIADLLDKGSGAVLLIDVNTYCGKDLVCYNQFSLFFVGAGGFGGKRTSEKAK 479
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
V V P RPPDA+L+D T+ +QAALYRLSGDWNPLH+DP+FA+L GF KPILHGLCTFGF
Sbjct: 480 VTVNPPKRPPDAILSDVTTSDQAALYRLSGDWNPLHLDPSFAALGGFQKPILHGLCTFGF 539
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
+AR VL+QFA+NDV+RFKAIK RFAKPV+PGQTLQTEMWKEGNRIHFQTKV+ETGD+ I+
Sbjct: 540 AARNVLKQFANNDVTRFKAIKVRFAKPVFPGQTLQTEMWKEGNRIHFQTKVKETGDLAIA 599
Query: 600 NAYVDLAPT-SGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGG 658
YVD+ SA P+ G LQS VFEEIGRR+K++G E+V+KVNAVF+W ITK G
Sbjct: 600 GGYVDIVSALDKPSALEPTAG--LQSDLVFEEIGRRIKEVGHELVRKVNAVFQWDITKDG 657
Query: 659 NIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARG 718
+WTIDLK+GSG VYQGPA+ +ADTT LSD+DFM+VV K +PQKAFFSG+LK +G
Sbjct: 658 KTAVQWTIDLKNGSGSVYQGPARSSADTTFTLSDQDFMDVVQKKTNPQKAFFSGKLKVKG 717
Query: 719 NIMLSQKLQMILKDYAKL 736
NIMLSQKL+MILKDYAKL
Sbjct: 718 NIMLSQKLEMILKDYAKL 735
>ref|NP_001086063.1| MGC81885 protein [Xenopus laevis]
gb|AAH74145.1| MGC81885 protein [Xenopus laevis]
Length = 741
Score = 1131 bits (2927), Expect = 0.0, Method: Composition-based stats.
Identities = 522/739 (70%), Positives = 619/739 (83%), Gaps = 4/739 (0%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
LRFDGRVVLVTGAG GLGR YALAFAERGA VVVNDLGGD KG GK S AADKVVEE
Sbjct: 3 SQVLRFDGRVVLVTGAGGGLGRTYALAFAERGASVVVNDLGGDIKGEGKSSFAADKVVEE 62
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR +GGKAVANYDSVE GEK+V++ALDAFGRID+++NNAGILRDRSFARISD DWDIIHR
Sbjct: 63 IRAKGGKAVANYDSVEAGEKLVQSALDAFGRIDIIINNAGILRDRSFARISDADWDIIHR 122
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHL+GSF +TRAAW HMK QK+GRIIMTSSA+GIYGNFGQANYSAAKLGL+GL+N+LAIE
Sbjct: 123 VHLKGSFLITRAAWNHMKNQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLVGLSNTLAIE 182
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K NI N IAP AGSR+TQTVMP+DL++ALKPEYV PLVLWLCHE C+E G LFEVGA
Sbjct: 183 GTKYNIQSNCIAPTAGSRLTQTVMPQDLLDALKPEYVTPLVLWLCHERCQETGSLFEVGA 242
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
GW+GKLRWER+LGAI+RQ N PMTPEAV+ W KICDF+NA KPQ+IQ+S + +VLS+
Sbjct: 243 GWVGKLRWERSLGAIIRQTNRPMTPEAVRDEWAKICDFDNADKPQTIQDSINPLYQVLSQ 302
Query: 302 IDSEGGVSANHTSRAT--STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+DSE GVS N TS T S+++ A AIGQKLP Y Y+ LE I+YALGVG S +DP
Sbjct: 303 VDSEKGVSMNPTSHGTSLSSSSIDPAKAIGQKLPVTLYKYSHLEPILYALGVGMSTRDPD 362
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
LKF+YEGS DFSCLP+FGV++ Q + M GGLA +PGL+I+F +VLHGEQYLE+YKPLP
Sbjct: 363 HLKFLYEGSEDFSCLPSFGVVVSQAAFMSGGLASVPGLNIDFTRVLHGEQYLEVYKPLPT 422
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVK 479
+G++ A VAD++DKGSG +I++DV++Y +LIC+NQFS+F+VG+GGFGGKR+S K K
Sbjct: 423 SGEMTSHATVADIMDKGSGAIILLDVHTYHGADLICYNQFSVFVVGAGGFGGKRSSSKAK 482
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
P+RPPD V D T+ +QAALYRLSGDWNPLHIDP+FA+L GF++PILHGLC+FGF
Sbjct: 483 ATENPPSRPPDVVEIDVTNADQAALYRLSGDWNPLHIDPSFAALGGFERPILHGLCSFGF 542
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VL+ FA+NDV++FKAIK RFAKPV PGQTLQTEMWKEGNRI QTKV+ETG+I I+
Sbjct: 543 SARHVLKHFANNDVTKFKAIKVRFAKPVLPGQTLQTEMWKEGNRIFLQTKVKETGEIAIA 602
Query: 600 NAYVDLAPTSGTS-AKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGG 658
AYVDLA T +K + G LQS VFEEI RR+KD+G ++VKKVNAVF+W ITK G
Sbjct: 603 GAYVDLASTVNNPESKAAVQDGGLQSDLVFEEISRRVKDVGGQLVKKVNAVFQWDITKDG 662
Query: 659 NIGAKWTIDLKS-GSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKAR 717
++WTIDLKS GSG+VY+G A+G ADT+ LSDEDFME+VLGK++PQKAFF+G+LK +
Sbjct: 663 KTASQWTIDLKSGGSGEVYRGKARGRADTSFTLSDEDFMELVLGKVNPQKAFFAGKLKVK 722
Query: 718 GNIMLSQKLQMILKDYAKL 736
GNIMLSQKL+MILKDYAKL
Sbjct: 723 GNIMLSQKLEMILKDYAKL 741
>ref|XP_001378211.1| PREDICTED: similar to 17beta-hydroxysteroid dehydrogenase
[Monodelphis domestica]
Length = 719
Score = 1118 bits (2892), Expect = 0.0, Method: Composition-based stats.
Identities = 561/700 (80%), Positives = 641/700 (91%), Gaps = 1/700 (0%)
Query: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVV 97
VNDLGGDFKGVG+ S AAD VVEEI++RGGKAVANYDSVE GEKVVKTALDAFG+ID+V+
Sbjct: 20 VNDLGGDFKGVGRSSSAADNVVEEIKKRGGKAVANYDSVEAGEKVVKTALDAFGKIDIVI 79
Query: 98 NNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYG 157
NNAGILRDRSF RISDEDWDIIH+VHLRGSFQVTRAAW+HMKKQK+GRIIMTSSASGIYG
Sbjct: 80 NNAGILRDRSFVRISDEDWDIIHKVHLRGSFQVTRAAWDHMKKQKFGRIIMTSSASGIYG 139
Query: 158 NFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEY 217
NFGQANYSAAKLGL GL+N+LAIEGRK NIHCNTIAP AGSRMT++VMP+DLV+ALKP+Y
Sbjct: 140 NFGQANYSAAKLGLAGLSNTLAIEGRKFNIHCNTIAPTAGSRMTESVMPQDLVDALKPDY 199
Query: 218 VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKIC 277
VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKN PMTPEAVKANW+KIC
Sbjct: 200 VAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNQPMTPEAVKANWRKIC 259
Query: 278 DFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSY 337
DFENA+ PQ+IQEST S+IEVL+KIDS+GGVS NHTS+A S T+ F AIG KLPP ++
Sbjct: 260 DFENANHPQTIQESTASVIEVLNKIDSQGGVSMNHTSQAASATTAAFTTAIGYKLPPRTF 319
Query: 338 AYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGL 397
+YTELEAIMYALGVGAS+K+P++LKF+YEG+SDFSCLPTFGVI QK MM GGL+E+PGL
Sbjct: 320 SYTELEAIMYALGVGASVKNPENLKFVYEGNSDFSCLPTFGVIPAQKCMMDGGLSEVPGL 379
Query: 398 SINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHN 457
+I++ KVLHGEQYLELYKPLP+ G+L EA++ D+LDKGSG+VI++DVYSYS KELIC N
Sbjct: 380 TIDYTKVLHGEQYLELYKPLPKTGQLTNEAIIVDILDKGSGLVILLDVYSYSGKELICFN 439
Query: 458 QFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHID 517
QF++F+VGSGGFGGK+TSDK KV V P RPPDA+LTDTTSLNQA LYRLSGDWNPLHID
Sbjct: 440 QFTVFVVGSGGFGGKKTSDKAKVTVPPPKRPPDAILTDTTSLNQAVLYRLSGDWNPLHID 499
Query: 518 PNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEM 577
P+FASL GF+KPILHGLC+FG++AR +LQQF +NDVSRF+AIKARFAKPVYPGQTL TEM
Sbjct: 500 PSFASLGGFEKPILHGLCSFGYAARHILQQFGNNDVSRFRAIKARFAKPVYPGQTLLTEM 559
Query: 578 WKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGT-SAKTPSEGGKLQSTFVFEEIGRRLK 636
WKEGNRIHFQTKVQETGDIV+SNAYVDL PTS S K S+ G LQST VFEEIGRR+K
Sbjct: 560 WKEGNRIHFQTKVQETGDIVLSNAYVDLVPTSDVLSTKVSSKDGTLQSTLVFEEIGRRIK 619
Query: 637 DIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFM 696
D+G E+VKKVNAVF+W+ITK G A+WTIDLK+GSG++YQGPA+G+ADT+ LSDE+FM
Sbjct: 620 DVGKELVKKVNAVFQWNITKHGQTAAQWTIDLKNGSGELYQGPARGSADTSFTLSDENFM 679
Query: 697 EVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
EVVLGKL+PQKAFFSG+L+ +GNIMLSQKL+MILKD+AKL
Sbjct: 680 EVVLGKLNPQKAFFSGKLQVKGNIMLSQKLEMILKDHAKL 719
>gb|AAK27967.1|AF241285_1 17-beta-hydroxysteroid dehydrogenase type 4 [Danio rerio]
Length = 725
Score = 1111 bits (2874), Expect = 0.0, Method: Composition-based stats.
Identities = 501/736 (68%), Positives = 598/736 (81%), Gaps = 11/736 (1%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M PLRFDG+VVLVTGAG GLGR YALAF +RGA V+VNDLGGD KG GK S AADKVVE
Sbjct: 1 MSVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAVIVNDLGGDIKGGGKSSAAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAVANYDSVE+GEK+++TALDAFGRIDVVVNNAGILRDRSFAR SD DWD+I
Sbjct: 61 EIRAAGGKAVANYDSVEDGEKLIQTALDAFGRIDVVVNNAGILRDRSFARTSDVDWDLIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMK+QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGLAN+LAI
Sbjct: 121 RVHLRGSFLVTRAAWNHMKQQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K NIHCNTIAP AGSR+T+TVMP DLV++LK EYVAPLVLWLCHESC+EN GLFEVG
Sbjct: 181 EGQKYNIHCNTIAPTAGSRLTETVMPPDLVQSLKAEYVAPLVLWLCHESCQENSGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LG IVRQK+ +TPEAV+ W+ ICDF NA+KP SIQES +++EVLS
Sbjct: 241 AGWIGKLRWERSLGRIVRQKSECVTPEAVRDAWRDICDFTNATKPASIQESLQTLVEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
+++ E + AN T+ AT+ A AIG LP ++ +T + I+YALGVG S +DP+
Sbjct: 301 RVEDERKIGANPTAVATN-----PAQAIGHVLPDMTFTHTHMNCILYALGVGVSSRDPQQ 355
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEG + FSCLPTFGVI Q +++G L IPGL I+F ++LHGEQYLELYKPLP +
Sbjct: 356 LQFLYEGHTHFSCLPTFGVIPAQGALLG--LGSIPGLDIDFTRLLHGEQYLELYKPLPTS 413
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G L A VADVLDKGSG++I++DV++YSE+EL+C+NQFS+F+VGSGGFGGKR S K
Sbjct: 414 GTLTSRATVADVLDKGSGMLILLDVHTYSEQELLCYNQFSVFIVGSGGFGGKRVSQKAVA 473
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
A P+RP DAV+ + TS +QAALYRLSGDWNPLHIDPNFA++ GF PILHGLC+FGF+
Sbjct: 474 PAAPPDRPADAVVVEETSKDQAALYRLSGDWNPLHIDPNFAAMGGFQSPILHGLCSFGFA 533
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VL+QFA NDVSRFKA+K RF KPVYPGQ+LQTEMWKE +R+H Q V+E+G +V+S
Sbjct: 534 ARHVLKQFAGNDVSRFKAMKVRFVKPVYPGQSLQTEMWKENSRVHIQCTVKESGAVVLSG 593
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AY+DL P + + P +LQS VF EI RR+KD G E+VKKVNAVF W IT G
Sbjct: 594 AYIDLHPAASVNTGPPQ--TELQSDLVFAEIERRIKDSGEELVKKVNAVFGWEITTDGET 651
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
WT+DLK+G G V + A AD T +SD+DFMEVV+GKL+PQKAFF+G+LK +GNI
Sbjct: 652 RRHWTVDLKTGRGSVQRAAA--KADVTFTVSDQDFMEVVMGKLNPQKAFFAGKLKVKGNI 709
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKL+ +LKD A+L
Sbjct: 710 MLSQKLEAVLKDQARL 725
>ref|NP_956430.1| hydroxysteroid (17-beta) dehydrogenase 4 [Danio rerio]
gb|AAN62014.1|AF439319_1 17-beta-hydroxysteroid dehydrogenase type 4 [Danio rerio]
gb|AAH44422.1| Hydroxysteroid (17-beta) dehydrogenase 4 [Danio rerio]
gb|AAI65653.1| Hsd17b4 protein [synthetic construct]
Length = 725
Score = 1111 bits (2874), Expect = 0.0, Method: Composition-based stats.
Identities = 501/736 (68%), Positives = 598/736 (81%), Gaps = 11/736 (1%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M PLRFDG+VVLVTGAG GLGR YALAF +RGA V+VNDLGGD KG GK S AADKVVE
Sbjct: 1 MSVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAVIVNDLGGDIKGGGKSSAAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAVANYDSVE+GEK+++TALDAFGRIDVVVNNAGILRDRSFAR SD DWD+I
Sbjct: 61 EIRAAGGKAVANYDSVEDGEKLIQTALDAFGRIDVVVNNAGILRDRSFARTSDVDWDLIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMK+QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGLAN+LAI
Sbjct: 121 RVHLRGSFLVTRAAWNHMKQQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K NIHCNTIAP AGSR+T+TVMP DLV++LK EYVAPLVLWLCHESC+EN GLFEVG
Sbjct: 181 EGQKYNIHCNTIAPTAGSRLTETVMPPDLVQSLKAEYVAPLVLWLCHESCQENSGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LG IVRQK+ +TPEAV+ W+ ICDF NA+KP SIQES +++EVLS
Sbjct: 241 AGWIGKLRWERSLGRIVRQKSECVTPEAVRDAWRDICDFTNATKPASIQESLQTLVEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
+++ E + AN T+ AT+ A AIG LP ++ +T + I+YALGVG S +DP+
Sbjct: 301 RVEDERKIGANPTAVATN-----PAQAIGHVLPDMTFTHTHMNCILYALGVGVSSRDPQQ 355
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEG + FSCLPTFGVI Q +++G L IPGL I+F ++LHGEQYLELYKPLP +
Sbjct: 356 LQFLYEGHTHFSCLPTFGVIPAQGALLG--LGSIPGLDIDFTRLLHGEQYLELYKPLPTS 413
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G L A VADVLDKGSG++I++DV++YSE+EL+C+NQFS+F+VGSGGFGGKR S K
Sbjct: 414 GTLTSRATVADVLDKGSGMLILLDVHTYSEQELLCYNQFSVFIVGSGGFGGKRVSQKAVA 473
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
A P+RP DAV+ + TS +QAALYRLSGDWNPLHIDPNFA++ GF PILHGLC+FGF+
Sbjct: 474 PAAPPDRPADAVVVEETSRDQAALYRLSGDWNPLHIDPNFAAMGGFQSPILHGLCSFGFA 533
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VL+QFA NDVSRFKA+K RF KPVYPGQ+LQTEMWKE +R+H Q V+E+G +V+S
Sbjct: 534 ARHVLKQFAGNDVSRFKAMKVRFVKPVYPGQSLQTEMWKENSRVHIQCTVKESGAVVLSG 593
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AY+DL P + + P +LQS VF EI RR+KD G E+VKKVNAVF W IT G
Sbjct: 594 AYIDLHPAASVNTGPPQ--TELQSDLVFAEIERRIKDSGEELVKKVNAVFGWEITTDGET 651
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
WT+DLK+G G V + A AD T +SD+DFMEVV+GKL+PQKAFF+G+LK +GNI
Sbjct: 652 RRHWTVDLKTGRGSVQRAAA--KADVTFTVSDQDFMEVVMGKLNPQKAFFAGKLKVKGNI 709
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKL+ +LKD A+L
Sbjct: 710 MLSQKLEAVLKDQARL 725
>gb|AAH65945.1| Hsd17b4 protein [Danio rerio]
Length = 725
Score = 1107 bits (2864), Expect = 0.0, Method: Composition-based stats.
Identities = 500/736 (67%), Positives = 596/736 (80%), Gaps = 11/736 (1%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M PLRFDG+VVLVTGAG GLGR YALAF +RGA V+VNDLGGD KG GK S AADKVVE
Sbjct: 1 MSVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAVIVNDLGGDIKGGGKSSAAADKVVE 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR GGKAVANYDSVE+GEK+++TALDAFGRIDVVVNNAGILRDRSFAR SD DWD+I
Sbjct: 61 EIRAAGGKAVANYDSVEDGEKLIQTALDAFGRIDVVVNNAGILRDRSFARTSDVDWDLIQ 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMK+QK+GRIIMTSSA+GIYGNFGQANYSAAKLGLLGLAN+LAI
Sbjct: 121 RVHLRGSFLVTRAAWNHMKQQKFGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLANTLAI 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG+K NIHCNTIAP AGSR+T+TVMP DLV++LK EYVAPLVLWLCHESC+EN GLFEVG
Sbjct: 181 EGQKYNIHCNTIAPTAGSRLTETVMPPDLVQSLKAEYVAPLVLWLCHESCQENSGLFEVG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGWIGKLRWER+LG IVRQK+ +TPEAV+ W+ ICDF NA+KP SIQES +++EVLS
Sbjct: 241 AGWIGKLRWERSLGRIVRQKSECVTPEAVRDAWRDICDFTNATKPASIQESLQTLVEVLS 300
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
+++ E + AN T+ AT+ A AIG LP ++ +T + I+YALGVG S +DP+
Sbjct: 301 RVEDERKIEANPTAVATN-----PAQAIGHVLPDMTFTHTHMNCILYALGVGVSSRDPQQ 355
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+F+YEG + FSCLPTFGVI Q +++G L IPGL I+F ++LHGEQYLELYK LP +
Sbjct: 356 LQFLYEGHTHFSCLPTFGVIPAQGALLG--LGSIPGLDIDFTRLLHGEQYLELYKSLPTS 413
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKV 480
G L A VADVLDKGSG++I++DV++YSE+EL+C+NQFS+F+VGSGGFGGKR S K
Sbjct: 414 GTLTSRATVADVLDKGSGMLILLDVHTYSEQELLCYNQFSVFIVGSGGFGGKRVSQKAVA 473
Query: 481 AVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFS 540
A P+RP DAV+ + TS +QAALYRLSGDWNPLHIDPNFA++ GF PILHGLC+FGF+
Sbjct: 474 PAAPPDRPADAVVVEETSKDQAALYRLSGDWNPLHIDPNFAAMGGFQSPILHGLCSFGFA 533
Query: 541 ARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISN 600
AR VL+QFA NDVSRFKA+K RF KPVYPGQ+LQTEMWKE +R+H Q V+E+G +V+S
Sbjct: 534 ARHVLKQFAGNDVSRFKAMKVRFVKPVYPGQSLQTEMWKENSRVHIQCTVKESGAVVLSG 593
Query: 601 AYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNI 660
AY+DL P + + P +LQS VF EI RR+KD G E+VKKVNAVF W IT G
Sbjct: 594 AYIDLHPAASVNTGPPQ--TELQSDLVFAEIERRIKDSGEELVKKVNAVFGWEITTDGET 651
Query: 661 GAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNI 720
WT+DLK+G G V + A AD T +SD DFMEVV+GKL+PQKAFF+G+LK +GNI
Sbjct: 652 RRHWTVDLKTGRGSVQRAAA--KADVTFTVSDRDFMEVVMGKLNPQKAFFAGKLKVKGNI 709
Query: 721 MLSQKLQMILKDYAKL 736
MLSQKL+ +LKD A+L
Sbjct: 710 MLSQKLEAVLKDQARL 725
>ref|XP_001512505.1| PREDICTED: similar to 17beta-hydroxysteroid dehydrogenase
[Ornithorhynchus anatinus]
Length = 752
Score = 1082 bits (2800), Expect = 0.0, Method: Composition-based stats.
Identities = 502/710 (70%), Positives = 596/710 (83%), Gaps = 12/710 (1%)
Query: 39 NDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVN 98
NDLGGDFKG GK S AA KVVEEIR++GGKAVANYDSVE GEK+VK ALDAFGRID+V+N
Sbjct: 43 NDLGGDFKGEGKSSSAAAKVVEEIRKKGGKAVANYDSVEAGEKIVKAALDAFGRIDIVIN 102
Query: 99 NAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGN 158
NAGILRDRSF RISD DWDIIHRVHLRGSFQVTRAAW+HMK+Q +GRIIMTSSA+GIYGN
Sbjct: 103 NAGILRDRSFVRISDHDWDIIHRVHLRGSFQVTRAAWDHMKQQNFGRIIMTSSAAGIYGN 162
Query: 159 FGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYV 218
FGQANYSAAKLGL+GL+N+LAIEGRK NIHCN+IAP AGSR+TQTVM +D+V+ALKPEYV
Sbjct: 163 FGQANYSAAKLGLVGLSNTLAIEGRKYNIHCNSIAPTAGSRLTQTVMTQDMVDALKPEYV 222
Query: 219 APLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICD 278
APLVLWLCHESC ENGGLFEVGAGWIGKLRWERTLGAIVRQKN PMTPEAVKA+WKKICD
Sbjct: 223 APLVLWLCHESCMENGGLFEVGAGWIGKLRWERTLGAIVRQKNQPMTPEAVKADWKKICD 282
Query: 279 FENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYA 338
F+N +KP++I+ESTG ++EVLSKI+ G VS N TS+A S A S + K+ P+++
Sbjct: 283 FDNVTKPRTIEESTGGMLEVLSKIEDGGAVSMNPTSQAASVAKSQLDRVVEYKISPWTFE 342
Query: 339 YTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLS 398
Y++LE I+YAL VGAS+K+P D+KF+YE +++FSCLPTFGVI QK + G ++IPG+
Sbjct: 343 YSQLETIIYALAVGASVKNPDDMKFVYERNANFSCLPTFGVIPAQKCLSTGLFSDIPGIQ 402
Query: 399 INFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQ 458
IN K+LHGEQYLE+YK P +GKL E V+ADVLDKGSG VI+ DV +Y EKELIC+NQ
Sbjct: 403 INMEKLLHGEQYLEVYKLFPSSGKLWSEGVIADVLDKGSGSVILFDVTTYHEKELICYNQ 462
Query: 459 FSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDP 518
FSLF++GSGGFGGKRTS+KVK ++ +P+RPPDAV D TSLNQAALYRLSGDWNPLHIDP
Sbjct: 463 FSLFVIGSGGFGGKRTSEKVKPSLPVPDRPPDAVCYDVTSLNQAALYRLSGDWNPLHIDP 522
Query: 519 NFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMW 578
+FA+L GF+KPILHGLC+FGFSAR VL QFADND +RF+AIK RFAKPVYPGQTLQTEMW
Sbjct: 523 DFAALGGFEKPILHGLCSFGFSARHVLHQFADNDPARFRAIKVRFAKPVYPGQTLQTEMW 582
Query: 579 KEGNRIHFQTKVQETGDIVISNAYVDLAPTSG-----------TSAKTPSE-GGKLQSTF 626
K GNRIHFQTKV ETG+IVISNAYVDL P+S S + PS LQS
Sbjct: 583 KNGNRIHFQTKVTETGNIVISNAYVDLVPSSDETSDNRTIKVGESTRIPSLCVEGLQSNI 642
Query: 627 VFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADT 686
+F+ IG+R+K+IG E+VKKV+AV + +ITKGG A WTIDLK+GSG+VYQGPAK
Sbjct: 643 IFDVIGQRIKEIGKELVKKVSAVIQLNITKGGKTAAIWTIDLKNGSGEVYQGPAKVPPQA 702
Query: 687 TIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
T LSDEDF+++V+G+L+P +AFF+GR+K GN++++ L MILK Y+KL
Sbjct: 703 TFTLSDEDFVKIVVGRLNPHQAFFNGRIKVEGNLIIAHNLNMILKTYSKL 752
>ref|XP_001624936.1| predicted protein [Nematostella vectensis]
gb|EDO32836.1| predicted protein [Nematostella vectensis]
Length = 725
Score = 1051 bits (2719), Expect = 0.0, Method: Composition-based stats.
Identities = 429/738 (58%), Positives = 545/738 (73%), Gaps = 18/738 (2%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
P+RFDGRVVLVTGAG GLGR YALAFAERGA VVVNDLGGD KG GK AADKVV+E
Sbjct: 3 AEPIRFDGRVVLVTGAGNGLGRQYALAFAERGASVVVNDLGGDTKGEGKSGRAADKVVQE 62
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR +GGKAVA+Y+SVE+G++VV+TA+ AFGRIDVVVNNAGILRD+S R+S+ DWD++ R
Sbjct: 63 IRAKGGKAVADYNSVEQGDQVVETAIKAFGRIDVVVNNAGILRDKSILRMSELDWDLVQR 122
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHL+GSF VTRAAW HMKKQK+GRIIMT+S SGIYGNFGQANYSAAKLGL+GL+N+LA E
Sbjct: 123 VHLKGSFLVTRAAWPHMKKQKFGRIIMTTSTSGIYGNFGQANYSAAKLGLVGLSNTLAQE 182
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K NI CN IAP AGSR+T+TVM ++++EALKPEY+APLVL+LCHESCEEN GLFE
Sbjct: 183 GAKYNIKCNAIAPVAGSRLTKTVMSDEMIEALKPEYIAPLVLYLCHESCEENAGLFETAV 242
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
GW + RW+RT G ++R++ +TPE V+ NW+ I D+ +A P + +V K
Sbjct: 243 GWFSQTRWQRTKGKLLRKEVEFVTPEMVRDNWEGITDWTDAENPTEASNVLQFVEDV--K 300
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIK-DPKD 360
+ +A + S S + QK+P +YT + I+YALGVG S + D
Sbjct: 301 EARQEQENARNASPGKS---------MTQKMPDAKKSYTHNDVILYALGVGVSFQEDYSH 351
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
LKF+YE DF+ LPTFG+I+GQ SMMG E+ G+ + AK+LHGEQYLE+YKPLP +
Sbjct: 352 LKFLYENHEDFAALPTFGIILGQGSMMGIAGGEMAGIKFDPAKLLHGEQYLEVYKPLPTS 411
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGKRTSDKVK 479
G + A V DVLDKG G +++++V + E +E IC NQFS++L G+GGFGGKR+SDKVK
Sbjct: 412 GSITNRAEVVDVLDKGKGALVLLNVTTLDEQEEPICFNQFSIYLGGAGGFGGKRSSDKVK 471
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
V+ P+R PDA + + T L QAALYRLSGD+NPLH+DP FA + G KPILHGLC+ G+
Sbjct: 472 PVVSPPSRTPDASVKEKTGLTQAALYRLSGDYNPLHVDPAFAQMGGLSKPILHGLCSLGY 531
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
SAR VL+Q+A+NDVS+FKA+K RF+KPV PGQT+QT+MWKEG+R+HFQ+KV E G +VIS
Sbjct: 532 SARHVLKQYANNDVSKFKALKVRFSKPVVPGQTIQTDMWKEGSRVHFQSKVVENGTVVIS 591
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
AYVD T T PS G L+S +F E+ +R+ D P++VKKV +F WH+ KGG
Sbjct: 592 GAYVDF--TELTPNIPPSSSG-LKSEALFAELKKRVSD-HPDLVKKVKGIFLWHVKKGGK 647
Query: 660 IGAKWTIDLKSGSGKVYQGPAK-GAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARG 718
+ + WT+DLK+ G V+ GP K G DTTI DED + + GK +PQ+ F G+LK G
Sbjct: 648 VVSSWTVDLKTPGGAVFTGPPKGGKPDTTITCEDEDLISMATGKANPQQLFMKGKLKVAG 707
Query: 719 NIMLSQKLQMILKDYAKL 736
NIML+ KL + KDYAK+
Sbjct: 708 NIMLTMKLNQLFKDYAKI 725
>gb|EAW48910.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_a [Homo
sapiens]
Length = 596
Score = 1013 bits (2621), Expect = 0.0, Method: Composition-based stats.
Identities = 596/599 (99%), Positives = 596/599 (99%), Gaps = 3/599 (0%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQK IIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG
Sbjct: 1 MKKQK---IIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 57
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV
Sbjct: 58 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 117
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 317
RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT
Sbjct: 118 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 177
Query: 318 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF
Sbjct: 178 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 237
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS
Sbjct: 238 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 297
Query: 438 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 497
GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT
Sbjct: 298 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 357
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK
Sbjct: 358 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 417
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS
Sbjct: 418 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 477
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ
Sbjct: 478 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 537
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 538 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 596
>ref|XP_001606624.1| PREDICTED: similar to estradiol 17 beta-dehydrogenase [Nasonia
vitripennis]
Length = 722
Score = 1008 bits (2608), Expect = 0.0, Method: Composition-based stats.
Identities = 373/736 (50%), Positives = 492/736 (66%), Gaps = 30/736 (4%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
LRFDGRVV+VTGAGAGLGRAYAL F RGA VVVNDLGG G G + AD VV+E
Sbjct: 3 TDNLRFDGRVVIVTGAGAGLGRAYALLFGSRGASVVVNDLGGGRHGDGSSTKIADTVVDE 62
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR+ GGKAVANY++V +G+K+V+TA+DAFGRID+V+NNAGILRD+SF R+SD DWD+IH
Sbjct: 63 IRKLGGKAVANYNNVLDGDKIVQTAIDAFGRIDIVINNAGILRDKSFVRMSDTDWDLIHD 122
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VH++GS + TRAAW + +KQ +GR+I+TSS SG+YGNFGQANYSAAKLGL+GLAN+LAIE
Sbjct: 123 VHVKGSMKTTRAAWPYFRKQNFGRVILTSSNSGLYGNFGQANYSAAKLGLVGLANTLAIE 182
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K+NIH N I P A SR+T+ ++P + E LKPEY+AP+V WLCH+ C+ENG + E
Sbjct: 183 GVKNNIHTNVIVPTAASRLTEDILPPEFFEQLKPEYIAPVVAWLCHDDCKENGSIIESAI 242
Query: 242 GWIGKLRWERTLGAIV-RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
GW GK R R+ G ++ R N +TPEAV+ NW + D NA SIQE TG I+ L
Sbjct: 243 GWAGKCRIVRSNGHLLRRDMNDIVTPEAVRDNWNTVTDMTNAKAYDSIQEVTGEIMGSLE 302
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+ S S+ T+ YT +AI+YALGVGA+ ++ +D
Sbjct: 303 KLKSGNSSSSQEFVMQTN--------------------YTHRDAILYALGVGATRQELRD 342
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEI--PGLSINFAKVLHGEQYLELYKPLP 418
+ ++YE +FS +P+F V G +M L + P + ++ ++LHGEQYLE++K LP
Sbjct: 343 ICYLYENHENFSLIPSFYVTFGPMGLMTTTLVQDALPNVQLDPTRILHGEQYLEIHKKLP 402
Query: 419 RAGKLKCEAVVADVLDKGSGVVIIMDVYSYS--EKELICHNQFSLFLVGSGGFGGKRTSD 476
GK++ + DVLDKG G V+++ +Y + + NQ S F VG+GGFGG R S
Sbjct: 403 VEGKVESRFRIQDVLDKGKGAVVLVQYETYDVATGDKLTTNQISAFAVGAGGFGGPRNSR 462
Query: 477 KVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCT 536
+ V P R P +T TS +QAA+YRLSGD+NPLH+D N A++AGF +PILHGLC+
Sbjct: 463 HLVPCVEPPKRKPCVSVTQKTSPDQAAIYRLSGDYNPLHMDDNIATMAGFSEPILHGLCS 522
Query: 537 FGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDI 596
GFS R VLQ FAD D K +K RFAKPV PGQTL+T+MW+ GNRIHFQT V E
Sbjct: 523 LGFSTRHVLQTFADGDPDALKTLKVRFAKPVLPGQTLRTDMWRNGNRIHFQTTVVENNSN 582
Query: 597 VISNAYVDLAP--TSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHI 654
VI+ AY+DL T + S L+S VF ++ +K PE VKK+N VF + +
Sbjct: 583 VITGAYMDLKEVKTPSIMSNLCSAAKNLESDAVFAQMADYVKS-HPEQVKKINGVFHYIV 641
Query: 655 TKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRL 714
T G A WT+DLK VY+G +G DTT+ + D+D +++ LGKL+PQ AF G+L
Sbjct: 642 TSKGEPQADWTLDLK--KCVVYKGKPEGKVDTTLTIDDKDMIQLALGKLNPQMAFMKGKL 699
Query: 715 KARGNIMLSQKLQMIL 730
K +GNIML+QKL+ ++
Sbjct: 700 KIKGNIMLTQKLKSLI 715
>ref|XP_001652466.1| estradiol 17 beta-dehydrogenase [Aedes aegypti]
gb|EAT41321.1| estradiol 17 beta-dehydrogenase [Aedes aegypti]
Length = 719
Score = 1000 bits (2587), Expect = 0.0, Method: Composition-based stats.
Identities = 383/740 (51%), Positives = 500/740 (67%), Gaps = 33/740 (4%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
LR+DGRVV+VTGAGAGLGR YAL F RGA VVVNDLGG+F G GK + AADKVVEEI
Sbjct: 7 DQLRYDGRVVVVTGAGAGLGREYALLFGSRGAKVVVNDLGGNFHGQGKSN-AADKVVEEI 65
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R GG AVA+Y+SV +GEK+++TA++AFGR+DV++NNAGILRDRS ARISDEDW++IH V
Sbjct: 66 RSAGGTAVADYNSVVDGEKIIQTAMEAFGRVDVLINNAGILRDRSLARISDEDWNLIHDV 125
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
H++GSF TRAAW MKKQ +GRIIMTSS SG+YGNFGQANYSAAKLGL+GLAN++AIEG
Sbjct: 126 HMKGSFMTTRAAWPIMKKQNFGRIIMTSSNSGVYGNFGQANYSAAKLGLVGLANTVAIEG 185
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 242
+K+NIHCN I P A SRMT+ ++PE L LKP+ +AP+V +LCHESCE+NG + E AG
Sbjct: 186 QKNNIHCNVIVPTAASRMTEGILPEILFNELKPKLIAPVVAYLCHESCEDNGAIIESAAG 245
Query: 243 WIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
W K+ + R G+++R + +TPE V+ W K+ D A +I E++ S++EVL K
Sbjct: 246 WATKVHFVRGKGSVLRTSIDEDVTPEYVRNVWDKVTDMSEAKHLNAIGEASLSLVEVLEK 305
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDL 361
+ EG + N + +Y + + I+YALGVGA++ D DL
Sbjct: 306 L-REGKSAENSVTE--------------------TYKFNYKDVILYALGVGATVTDESDL 344
Query: 362 KFIYEGSSDFSCLPTFGVIIGQKSMMGGGLA--EIPGLSINFAKVLHGEQYLELYKPLPR 419
+F+YE +FS LPTF ++ G S+MG L IP + +LHGEQY+EL+ +P
Sbjct: 345 RFLYENHPEFSVLPTFFILPGLLSVMGSDLTAKAIPHAQFDLTNILHGEQYIELFDSVPT 404
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGK-RTSDK 477
G L + V DVLDK SG +++ S+ E L+ Q S F+VG G F GK + S +
Sbjct: 405 DGVLTTTSTVIDVLDKKSGALVVTQSESFDENGTLVARGQSSTFVVGVGNFNGKSKASSE 464
Query: 478 VKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTF 537
VK + P R PDA + TS +QAALYRLSGD NP+HIDP+F+++AG+ PILHGLCT
Sbjct: 465 VKALMPNPKRSPDASVQIKTSRDQAALYRLSGDLNPMHIDPSFSAIAGYKTPILHGLCTM 524
Query: 538 GFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKE-GNRIHFQTKVQETGDI 596
G S + VL+++ ++D S FKA K RF+KPV PGQTL+ +MWKE NR+ F+T V ET
Sbjct: 525 GISVKAVLKRYGNDDSSLFKAAKVRFSKPVLPGQTLRIDMWKEANNRVCFRTVVVETNTE 584
Query: 597 VISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITK 656
V+S AYVDL T G LQS VF I R+ + K +NAVF + IT
Sbjct: 585 VLSGAYVDLKKIVLKPNMTA--GKSLQSDAVFAGIKDRVSE-NEAKAKAINAVFLYKITD 641
Query: 657 GGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKA 716
GG + +W +DLK+ KVY+GP +G ADTT+ +SD D +++ LGKL PQ AF G+LK
Sbjct: 642 GGKVSKEWVLDLKNA--KVYEGPVQGKADTTMTISDSDMVDLALGKLQPQAAFMKGKLKI 699
Query: 717 RGNIMLSQKLQMILKDYAKL 736
GNIML+QKL +LK AKL
Sbjct: 700 TGNIMLAQKLAPLLKTEAKL 719
>emb|CAB55552.1| Fox2 protein [Glomus mosseae]
Length = 1015
Score = 995 bits (2574), Expect = 0.0, Method: Composition-based stats.
Identities = 373/757 (49%), Positives = 502/757 (66%), Gaps = 30/757 (3%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
L+FDG+V +VTGAG GLGRAYAL + GA VVVNDLG G G S AADKVVEE
Sbjct: 267 SEDLKFDGKVAIVTGAGGGLGRAYALLLGKLGASVVVNDLGVSAHGQGATSSAADKVVEE 326
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR+ GGKAVANYDSVE+GEK+V+TA+ AFGR+D+++NNAGILRD+SFAR++D+DWD++ R
Sbjct: 327 IRQAGGKAVANYDSVEDGEKIVETAIKAFGRVDIIINNAGILRDKSFARMTDQDWDLVQR 386
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHLRG+++VT+AAW ++ KQKYGRII T+S+ G+YGNFGQANYS AKLG+LG +N+LA+E
Sbjct: 387 VHLRGTYKVTKAAWPYLTKQKYGRIINTASSVGLYGNFGQANYSTAKLGILGFSNTLALE 446
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
GRK+NI NTIAPNAG+RMT T+ P D+VEA KP+YVAP V +L HE+C G +FEVG
Sbjct: 447 GRKNNIFVNTIAPNAGTRMTATIWPPDMVEAFKPDYVAPFVSFLAHEACPSTGNVFEVGG 506
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN--ASKPQSIQESTGSIIEVL 299
GW+ ++RW+R G +TPE + + I +F++ A+ P + Q++ E
Sbjct: 507 GWVAQVRWQRAGGIGFPTS-KALTPEDIASKIDIITNFDDGRATHPTTTQQALQQFFENF 565
Query: 300 SKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+ ++ S S++ + + A +K P + Y E + ++YALG+GA+ K
Sbjct: 566 AN--AQKSESGQSKSKSNN-SKIDVEAAKKRKFEPHVFEYKERDVMLYALGIGAT---RK 619
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPR 419
DL+++YE S +FS +PTFGVI L+E+ G N +LHGEQYLEL KP+P
Sbjct: 620 DLQWVYENSDNFSVIPTFGVIPAIILSNTLPLSEVLG-DFNVMMLLHGEQYLELKKPIPT 678
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGKRTSDKV 478
+GKL V D+LDKG GV I + + E E+I NQ +LF+ G GGFGGK+T D
Sbjct: 679 SGKLISTPYVIDILDKGKGVSFIFGITTTDEKGEVIFENQTTLFIRGIGGFGGKKTGDDR 738
Query: 479 KVAVA---IPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLC 535
A A P R PD V+ + T+ NQAALYRLSGD+NPLHIDP+ +++ GFD PILHG+C
Sbjct: 739 GAATASNIPPKRAPDVVVKEKTNENQAALYRLSGDYNPLHIDPSMSAMGGFDVPILHGMC 798
Query: 536 TFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGD 595
TFG S + + F ND + FK+IKAR A PV+PG+TL+T+MWK+G+++ FQT+V E
Sbjct: 799 TFGISGKHIFSTFGKNDPNTFKSIKARLAAPVFPGETLETQMWKDGDKVIFQTRVVERDV 858
Query: 596 IVISNAYVDLAPTSG------TSAKTPSEGGKL---QSTFVFEEIGRRLKDIGP----EV 642
I I++A V+L +S + TPS G + QS+ VFE++ L P
Sbjct: 859 ICIASAAVELRGSSASGASMGAPSATPSAGISVPGFQSSSVFEQLKAGLDAASPAERQAQ 918
Query: 643 VKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGK 702
VKKV F+ +I W ID K+G G V GP+ AD TI +SD DFME+ GK
Sbjct: 919 VKKVKGSFQLNIKNAEGKEQSWYIDFKTGDGAVGIGPSPKKADATIGVSDADFMELASGK 978
Query: 703 LDPQKAFFSGRLKARGNIMLSQKLQMIL---KDYAKL 736
L+ QKAF SG+LK +GN+ML+ KL +L K +KL
Sbjct: 979 LNAQKAFMSGKLKIKGNMMLATKLGDVLAGGKSKSKL 1015
Score = 353 bits (907), Expect = 3e-95, Method: Composition-based stats.
Identities = 152/304 (50%), Positives = 203/304 (66%), Gaps = 44/304 (14%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
M LRFDGR V+VTGAG V+
Sbjct: 1 MAQELRFDGRTVIVTGAGG---------------------------------------VD 21
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EI + GGKAV+NY+SVE+G+K+V+TA+ AFGR+D+++NNAGILRD+SFARI+D DWD+I
Sbjct: 22 EIIKAGGKAVSNYNSVEDGDKIVETAMKAFGRVDILINNAGILRDKSFARITDSDWDLIQ 81
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
VH+RGS++VT+AAW+ +KQK+GRII T+SA+GIYGNFGQANY KL L+ +LA
Sbjct: 82 AVHVRGSYKVTKAAWDIFRKQKFGRIINTASAAGIYGNFGQANY--TKLALVSFTETLAK 139
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG K+NIH N IAP A SRMT++VMP D++ ALKP+YVAPLV++LCHES +ENG LFEVG
Sbjct: 140 EGAKANIHANVIAPIAASRMTESVMPPDVLAALKPDYVAPLVMYLCHESTQENGSLFEVG 199
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AG++ KLRWER+ GA+ + + P V W +I +F N + P S ++ + +L
Sbjct: 200 AGFVAKLRWERSKGAVFK-ADDTFLPGTVAVKWNEITEFTNPTYPTSPGDA--DFVGLLE 256
Query: 301 KIDS 304
K +
Sbjct: 257 KAKA 260
>ref|XP_393475.2| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
[Apis mellifera]
Length = 704
Score = 993 bits (2568), Expect = 0.0, Method: Composition-based stats.
Identities = 358/743 (48%), Positives = 477/743 (64%), Gaps = 46/743 (6%)
Query: 1 MGSP-LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVV 59
MG L F RVV++TGAGAGLGR YAL FA RGA VVVNDLGG G G + AD VV
Sbjct: 1 MGEEKLSFVNRVVIITGAGAGLGRTYALLFASRGASVVVNDLGGSRDGDGSSTKIADSVV 60
Query: 60 EEIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDII 119
EIR+ GG+AVANYDSV +GEK+VKTA+DAFGRID++VNNAGILRD+SFA++ + DWD+I
Sbjct: 61 NEIRKNGGRAVANYDSVLDGEKIVKTAIDAFGRIDILVNNAGILRDKSFAKMLESDWDLI 120
Query: 120 HRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLA 179
VHL+G+F+ T+AAW + KQKYGRIIMT+S SG+YGNFGQANYSAAK+GL+GL N+LA
Sbjct: 121 QNVHLKGAFKTTQAAWPYFVKQKYGRIIMTASNSGLYGNFGQANYSAAKMGLIGLTNTLA 180
Query: 180 IEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEV 239
IEG++ NIH N I P A SR+T+ ++P D + LKPE +AP+V+WLCHE C ENG + E
Sbjct: 181 IEGKQKNIHTNVIIPTAASRLTEDILPPDFFKELKPELIAPVVVWLCHEKCMENGSIIES 240
Query: 240 GAGWIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEV 298
GW GK R+ G+ +RQ + +TPE V+ W+ I D NA SI+E TG +
Sbjct: 241 ALGWAGKCHVIRSSGSTLRQDLSSEITPEDVENKWQVITDMSNAKHFNSIEEVTGEFMTT 300
Query: 299 LSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDP 358
+ SE + + + Y + I+YALGVGAS++ P
Sbjct: 301 IETTKSENSQPSESQNSGV-----------------LRHTYNYRDIILYALGVGASVQIP 343
Query: 359 KDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAE--IPGLSINFAKVLHGEQYLELYKP 416
D +++YE S+F+ LPTF V+ + + E +P + ++ K+LHGEQY+E+YK
Sbjct: 344 TDFRYLYENDSNFAVLPTFYVVYAPMVALEFSMYEKFLPHIELDPTKILHGEQYIEVYKQ 403
Query: 417 LPRAGKLKCEAVVADVLDKGSGVVII--MDVYSYSEKELICHNQFSLFLVGSGGFGGKRT 474
LP ++ + DV+DKG G +++ D + S ++ + Q +F++G+G F GKRT
Sbjct: 404 LPTEATVETRYKIVDVVDKGKGALVVIQHDTFDTSNEDKLSTGQMIIFVIGAGNFKGKRT 463
Query: 475 SDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGL 534
S + + PNR PD +T TS +QAALYRLSGD NPLHID N + +AGF +PILHGL
Sbjct: 464 SSYIIPTIESPNREPDTSVTQQTSQDQAALYRLSGDQNPLHIDSNMSMIAGFKRPILHGL 523
Query: 535 CTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETG 594
CT GFS R +LQ + D S FKAIK RFAKPV PGQTL+T+MW+EGNRIHFQT E
Sbjct: 524 CTLGFSVRHILQTYTGGDPSLFKAIKTRFAKPVIPGQTLRTDMWQEGNRIHFQTHTVEEN 583
Query: 595 DIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHI 654
+V+ N L+S VF +I +K E VKK+N VF +HI
Sbjct: 584 ILVVINT-------------------SLESDAVFFKIAEYVKTNSDE-VKKINGVFLYHI 623
Query: 655 TKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRL 714
G + A+WT+DLK +VY+G K D T+ L D D +++ LGKL+PQ AF +L
Sbjct: 624 LVNGKLKAQWTLDLK--KSEVYRGEPKSKPDATLTLEDADMIQMALGKLNPQVAFVRQKL 681
Query: 715 KARGNIMLSQKLQMILK-DYAKL 736
K GNIML+QKL+ +++ +KL
Sbjct: 682 KITGNIMLTQKLKTLIEASKSKL 704
>ref|XP_001088200.1| PREDICTED: hydroxysteroid (17-beta) dehydrogenase 4 isoform 3
[Macaca mulatta]
Length = 597
Score = 992 bits (2567), Expect = 0.0, Method: Composition-based stats.
Identities = 581/599 (96%), Positives = 588/599 (98%), Gaps = 2/599 (0%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG
Sbjct: 1 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 60
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV
Sbjct: 61 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 120
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 317
RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEG VSANHTS AT
Sbjct: 121 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEG-VSANHTSHAT 179
Query: 318 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKF+YEGSSDFSCLPTF
Sbjct: 180 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFVYEGSSDFSCLPTF 239
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVIIGQKS+MGGGLAEIPGLSINFAKV+ GE ++ KPL R GKLKCEAVVADVLDKGS
Sbjct: 240 GVIIGQKSLMGGGLAEIPGLSINFAKVI-GEPSMKAEKPLKRVGKLKCEAVVADVLDKGS 298
Query: 438 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 497
GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT
Sbjct: 299 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 358
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARR+LQQFADNDVSRFK
Sbjct: 359 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRILQQFADNDVSRFK 418
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTS TSAKTPS
Sbjct: 419 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSDTSAKTPS 478
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGGKLQST VFEEIGRRLKD+GPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ
Sbjct: 479 EGGKLQSTLVFEEIGRRLKDVGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 538
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 539 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 597
>ref|XP_001843060.1| peroxisomal multifunctional enzyme type 2 [Culex pipiens
quinquefasciatus]
gb|EDS30335.1| peroxisomal multifunctional enzyme type 2 [Culex pipiens
quinquefasciatus]
Length = 719
Score = 991 bits (2562), Expect = 0.0, Method: Composition-based stats.
Identities = 386/740 (52%), Positives = 498/740 (67%), Gaps = 33/740 (4%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
S LR+DGRVV+VTGAGAGLGR YAL F RGA VVVNDLGG+F G GK + AADKVVEEI
Sbjct: 7 SQLRYDGRVVVVTGAGAGLGREYALLFGSRGAKVVVNDLGGNFHGQGKSN-AADKVVEEI 65
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R RGG AVA+Y+SV +G+K+++TA++AFGR+DV+VNNAGILRD+S ARISDEDW++IH V
Sbjct: 66 RERGGTAVADYNSVVDGDKIIQTAMEAFGRVDVLVNNAGILRDKSIARISDEDWNLIHDV 125
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
HL+GSF TRAAW MKKQ YGRIIMTSS SG+YGNFGQANYSAAKLGL+GLAN++AIEG
Sbjct: 126 HLKGSFVTTRAAWPIMKKQNYGRIIMTSSNSGVYGNFGQANYSAAKLGLVGLANTVAIEG 185
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 242
K++IHCN I P A SRMT+ ++PE L LKP+ +AP+V +LCHESCE+ G + E AG
Sbjct: 186 AKNDIHCNVIVPTAASRMTEGILPEILFNELKPKLIAPVVAFLCHESCEDTGAIIESAAG 245
Query: 243 WIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
W K+ + R G+++R + +TPE VK W K+ D A +I E++ ++++VL K
Sbjct: 246 WATKVHFVRGKGSVLRTSLDESVTPEYVKGVWSKVTDMSEAKHLNAIGEASLTLVDVLEK 305
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDL 361
+ GV A ++ T Y + + I+YALGVGA++ D DL
Sbjct: 306 L--REGVPAGNSVTET-------------------YKFNYKDVILYALGVGATVTDENDL 344
Query: 362 KFIYEGSSDFSCLPTFGVIIGQKSMMGGGLA--EIPGLSINFAKVLHGEQYLELYKPLPR 419
+F+YE SDFS LPTF ++ G S+MG L I S + +LHGEQY+EL+ +P
Sbjct: 345 RFLYENHSDFSTLPTFFILPGLLSVMGSNLTASAITHASFDLTNILHGEQYIELFDNVPT 404
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGK-RTSDK 477
G L + V DVLDK SG ++I SY E L+ Q S F+VG G F GK + SD
Sbjct: 405 EGVLTTTSTVIDVLDKKSGALVITQSDSYDENGTLVARGQSSTFIVGVGNFNGKSKASDA 464
Query: 478 VKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTF 537
VK V P R PDA + T+ +QAALYRLSGD NP+HIDP+F+++AG+ PILHGLCT
Sbjct: 465 VKPLVPNPKRAPDASVQVKTTKDQAALYRLSGDLNPMHIDPSFSAIAGYKTPILHGLCTM 524
Query: 538 GFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKE-GNRIHFQTKVQETGDI 596
G S + VL+QF +D + FKA K RF+KPV PGQTL+ +MW+E NR+ F+T V ET
Sbjct: 525 GVSVKAVLKQFGGDDSALFKAAKVRFSKPVLPGQTLRVDMWREANNRVCFRTVVVETNTE 584
Query: 597 VISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITK 656
V+S AYVD T G LQS VF I R+ + K +NAV+ + IT
Sbjct: 585 VLSGAYVDFKQIVVKPNMT--SGKSLQSDAVFAGIKERIAE-NEAKAKSINAVYLYKITD 641
Query: 657 GGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKA 716
G + +W +D K +GKVY+GP +G ADTT+ +SD D +++ LGKL PQ AF G+LK
Sbjct: 642 SGKVAKEWVLDCK--AGKVYEGPVQGKADTTMTISDADMVDLALGKLQPQTAFMKGKLKI 699
Query: 717 RGNIMLSQKLQMILKDYAKL 736
GNIML+QKL +LK AKL
Sbjct: 700 TGNIMLAQKLAPLLKTEAKL 719
>emb|CAG09600.1| unnamed protein product [Tetraodon nigroviridis]
Length = 716
Score = 989 bits (2558), Expect = 0.0, Method: Composition-based stats.
Identities = 446/670 (66%), Positives = 540/670 (80%), Gaps = 1/670 (0%)
Query: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
L F+GRVVLVTGAG GLGR YALAFA+RGA VVVNDLGG+ KG GK S AADKVVEEIR
Sbjct: 3 LSFEGRVVLVTGAGGGLGREYALAFAQRGASVVVNDLGGNTKGGGKSSAAADKVVEEIRA 62
Query: 65 RGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHL 124
+GGKAVA+YDSVE+GEK++++AL+ FGRIDVVVNNAGILRDRSF R SD DWD+IHR+HL
Sbjct: 63 KGGKAVASYDSVEDGEKLIQSALERFGRIDVVVNNAGILRDRSFPRTSDVDWDLIHRIHL 122
Query: 125 RGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRK 184
RGSF VTRAAW+ MKKQK+GRIIMT+SA+GIYGNFGQ+NYS+AKLGLLGLAN+LAIEGRK
Sbjct: 123 RGSFLVTRAAWDQMKKQKFGRIIMTASAAGIYGNFGQSNYSSAKLGLLGLANTLAIEGRK 182
Query: 185 SNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWI 244
NIHCNT+AP AGSR+T+TVMP DLV +LKPEYVAPLVLWLCHE C+ENGGLFEVGAGW+
Sbjct: 183 YNIHCNTVAPVAGSRLTETVMPPDLVASLKPEYVAPLVLWLCHEQCQENGGLFEVGAGWV 242
Query: 245 GKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDS 304
GKLRWER+ G IVRQKN MTPEAV+ W +ICDF +A+KP S+QES + + VLS++D+
Sbjct: 243 GKLRWERSRGQIVRQKNRAMTPEAVRDGWDRICDFTDATKPSSVQESLQAFVSVLSQVDA 302
Query: 305 EGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFI 364
G V A+ + A + + + AIGQ LP ++ + + I+YALGVG S KDP L+F+
Sbjct: 303 GGQVEASPAAAAAAPSGINPSVAIGQILPRSTFTFNHTQCILYALGVGMSTKDPDHLRFL 362
Query: 365 YEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLK 424
YEG DFSCL FGVI Q + M G L +PGL+I+ ++LHGEQYLELY+PLP +G L
Sbjct: 363 YEGHPDFSCLSHFGVIPPQAAFMEG-LTSVPGLTIDLTQMLHGEQYLELYRPLPTSGTLT 421
Query: 425 CEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAI 484
EA +ADVLDKGSG V+++DV +YS +ELIC+NQFSLF+VG+GGFGGKRTS K K ++
Sbjct: 422 SEATIADVLDKGSGAVVLLDVNTYSGEELICYNQFSLFVVGAGGFGGKRTSAKSKASLPA 481
Query: 485 PNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRV 544
P R PD V+TD T+ +QAALYRLSGDWNPLHIDP+FA++ GF PILHGLC+FGF+AR V
Sbjct: 482 PKRAPDVVMTDCTTRDQAALYRLSGDWNPLHIDPSFAAIGGFKAPILHGLCSFGFAARHV 541
Query: 545 LQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVD 604
L+QFA+N+ SRFKAIK RF KPV PGQ+LQT MWKEG+RIH + V+ET D+V+S AYVD
Sbjct: 542 LKQFANNEPSRFKAIKVRFVKPVMPGQSLQTAMWKEGSRIHIECTVKETNDVVLSGAYVD 601
Query: 605 LAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKW 664
L + S + P++GG LQS VF EIGRR+K+ G E+VKKVNAVF W ITK G A W
Sbjct: 602 LHQAAEASPEPPAQGGALQSDLVFAEIGRRIKEAGSELVKKVNAVFSWEITKEGRTAAHW 661
Query: 665 TIDLKSGSGK 674
+ L G+
Sbjct: 662 SFLLGQAEGQ 671
>ref|XP_974784.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
[Tribolium castaneum]
Length = 715
Score = 987 bits (2552), Expect = 0.0, Method: Composition-based stats.
Identities = 390/741 (52%), Positives = 500/741 (67%), Gaps = 31/741 (4%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MG LRFDGRVV+VTGAGAGLGRAYAL F RGA VVVNDLGG G GK S AAD VVE
Sbjct: 1 MG-DLRFDGRVVVVTGAGAGLGRAYALLFGSRGAKVVVNDLGGGRHGDGKSSSAADAVVE 59
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EI+R GG AVA+Y+SV +GEKV+KTALD FGR+DV++NNAGILRD+SFARISD+DWD++H
Sbjct: 60 EIKRNGGTAVADYNSVVDGEKVIKTALDNFGRVDVLINNAGILRDKSFARISDQDWDLVH 119
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
VHL+GSF+ T+AA+ KKQ YGRIIMTSS SG+YGNFGQANYSAAK+GL+GLA+++AI
Sbjct: 120 AVHLKGSFKTTQAAFPIFKKQGYGRIIMTSSNSGLYGNFGQANYSAAKMGLVGLASTIAI 179
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG K+NIHCN I P A SR+T+ ++P DL LKPE +AP+V +LCHESC ENG + E
Sbjct: 180 EGAKNNIHCNVIVPTAASRLTEDILPPDLYAELKPELIAPVVAYLCHESCTENGSIIESA 239
Query: 241 AGWIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVL 299
AGW GK + R+ G+++R K ++ E V+ W+K+ NA SIQE+TG+++ L
Sbjct: 240 AGWAGKCQIIRSNGSLLRTKITDGVSVENVRDKWQKVTSMSNAEHLDSIQEATGALMTSL 299
Query: 300 SKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPK 359
+ S G V Y +T+ + I+YALGVGAS+K+P
Sbjct: 300 DSLRS-GEVKDEEVD---------------------VYNFTQKDIILYALGVGASLKNPN 337
Query: 360 DLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAE--IPGLSINFAKVLHGEQYLELYKPL 417
+LKFIYE DFS LPTF ++ ++M E IPG +++ A++LHGEQY+E +
Sbjct: 338 ELKFIYENDEDFSALPTFYIMPAMQAMFTSSKLESAIPGKTVSLAQILHGEQYIEFLGEV 397
Query: 418 PRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGKRTSD 476
P+ GKL + + +VLDKGSG I+ ++ ++ E L+ NQ F+VG+G FGG RT
Sbjct: 398 PKEGKLFSKNSIVEVLDKGSGAAIVQNIETFDEQGNLLIRNQTVAFVVGAGNFGGSRTGT 457
Query: 477 KVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCT 536
K + P R PD LTD T+++QAALYRLSGD NPLHIDPN A +AGF +PILHGLCT
Sbjct: 458 KAIPCQSKPPRVPDLSLTDKTTIDQAALYRLSGDTNPLHIDPNMAVVAGFKQPILHGLCT 517
Query: 537 FGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDI 596
GFS R +++ +A D S KA KARF KPV PGQTL+ + W+EG+RIHF+T V ET +
Sbjct: 518 LGFSIRLLVRAYAGGDPSFVKACKARFMKPVIPGQTLRVDFWREGSRIHFETSVVETNTV 577
Query: 597 VISNAYVDLAPTSGTSAKTPS-EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHIT 655
VI AYVDL S L+S VF+ I ++K P K + VF + IT
Sbjct: 578 VIGGAYVDLNSVKVMEPINNSVSAPALESDAVFQFIIDQVK-ADPNKAKSIGGVFLYKIT 636
Query: 656 KGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLK 715
K G +WT+DLK+ KVY+G +G TT+ ++DEDFM + GKL PQ AF G+LK
Sbjct: 637 KNGKEAKQWTMDLKNA--KVYEGAPEGKPSTTLTIADEDFMLLAQGKLQPQAAFMKGKLK 694
Query: 716 ARGNIMLSQKLQMILKDYAKL 736
GNIML+QKL ILK AKL
Sbjct: 695 ITGNIMLAQKLAPILKANAKL 715
>ref|XP_859266.1| PREDICTED: similar to Peroxisomal multifunctional enzyme type 2
(MFE-2) (D-bifunctional protein) (DBP)
(17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4)
isoform 3 [Canis familiaris]
Length = 599
Score = 983 bits (2542), Expect = 0.0, Method: Composition-based stats.
Identities = 520/599 (86%), Positives = 555/599 (92%)
Query: 138 MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAG 197
MKKQK+GRI+MTSSASGIYGNFGQA+YSAAKLGLLG +N+LAIEG+ SNIHCNTIAP AG
Sbjct: 1 MKKQKFGRIVMTSSASGIYGNFGQASYSAAKLGLLGFSNTLAIEGKTSNIHCNTIAPTAG 60
Query: 198 SRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIV 257
SRMTQTVM EDL++ALKP+YVAPLVLWLCHESCEENG LFEVG GWIGKLRWERTLGAIV
Sbjct: 61 SRMTQTVMAEDLLKALKPDYVAPLVLWLCHESCEENGSLFEVGGGWIGKLRWERTLGAIV 120
Query: 258 RQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRAT 317
RQKN P+TPEAVKANWKKICDF+NA+KPQSIQES S+I V++ IDS+GGVS NHTS A
Sbjct: 121 RQKNQPVTPEAVKANWKKICDFDNATKPQSIQESVASLIGVVNTIDSDGGVSTNHTSHAA 180
Query: 318 STATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTF 377
STATS FAGAIG K PPFS AYTELE IMYALGVGAS+K+PKD+KFIYEGS+DFSCLPTF
Sbjct: 181 STATSEFAGAIGHKFPPFSSAYTELETIMYALGVGASVKEPKDMKFIYEGSTDFSCLPTF 240
Query: 378 GVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGS 437
GVII QK ++GGGL+EIPG S+N AKVLHGEQYLELYKPLPRAG L+CEAVVADVLDKGS
Sbjct: 241 GVIIAQKFVIGGGLSEIPGFSVNLAKVLHGEQYLELYKPLPRAGNLRCEAVVADVLDKGS 300
Query: 438 GVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTT 497
G VI++DVYSY E+ELIC+NQFSLFLVGSGG GGKRTSDKVK VA+PNRPPDAVLTDTT
Sbjct: 301 GSVILVDVYSYFEEELICYNQFSLFLVGSGGTGGKRTSDKVKATVAVPNRPPDAVLTDTT 360
Query: 498 SLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFK 557
SLNQAALYRLSGDWNPLHIDPNFA AGFDKPILHGLCTFGFSAR VLQ+FADNDVSRFK
Sbjct: 361 SLNQAALYRLSGDWNPLHIDPNFAGFAGFDKPILHGLCTFGFSARHVLQKFADNDVSRFK 420
Query: 558 AIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPS 617
AIK RFAKPVYPGQTLQTEMWKEGNRIHFQTK+QETGDIVISNAYVDL PTS TSA+TPS
Sbjct: 421 AIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKIQETGDIVISNAYVDLMPTSDTSAQTPS 480
Query: 618 EGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQ 677
EGG+LQST VFEEIGRRLKDIG EV KKVNAVFEWHITKGGNI AKWTIDLKSG GKVYQ
Sbjct: 481 EGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGNIAAKWTIDLKSGFGKVYQ 540
Query: 678 GPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 736
GPAKG AD T LSDEDFM+VVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Sbjct: 541 GPAKGPADATFTLSDEDFMDVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL 599
>ref|XP_314766.4| AGAP008667-PA [Anopheles gambiae str. PEST]
gb|EAA10131.4| AGAP008667-PA [Anopheles gambiae str. PEST]
Length = 724
Score = 982 bits (2539), Expect = 0.0, Method: Composition-based stats.
Identities = 382/743 (51%), Positives = 493/743 (66%), Gaps = 35/743 (4%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
LR+DGRVV+VTGAGAGLGR YAL FA RGA VVVNDLGG+F G GK + AADKVVEE
Sbjct: 9 SKQLRYDGRVVVVTGAGAGLGREYALLFASRGAKVVVNDLGGNFHGQGKSN-AADKVVEE 67
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR GG AV +Y+SV EG+K+V+TAL+ FGRIDV+VNNAGILRDRS ARISDEDW++IH
Sbjct: 68 IRAAGGVAVPDYNSVVEGDKIVQTALENFGRIDVLVNNAGILRDRSLARISDEDWNLIHD 127
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHL+GSF TRAAW MKKQ YGRIIMTSS SG+YGNFGQANYSAAKLGL+GLAN++AIE
Sbjct: 128 VHLKGSFLTTRAAWPVMKKQNYGRIIMTSSNSGVYGNFGQANYSAAKLGLVGLANTVAIE 187
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K+NI CN I P A SRMT+ ++PE L LKP+ +AP+V +LCHESCE+ G + E A
Sbjct: 188 GAKNNIQCNVIVPTAASRMTEGILPEILFNELKPKLIAPVVAYLCHESCEDTGAIIESAA 247
Query: 242 GWIGKLRWERTLGAIVRQK-NHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
GW K+ + R G ++R + ++PE V+ W ++ D A + +I E++ S++ VL
Sbjct: 248 GWATKVHFVRGRGCVLRTSIDEDVSPEYVQQVWNRVTDMSEAKRLNAIGEASLSLVGVLE 307
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
K+ N+ + T T + Y +AI+YALGVGAS+ DP D
Sbjct: 308 KLRDG----QNNENSVTET-----------------FRYGFKDAILYALGVGASVTDPTD 346
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLA--EIPGLSINFAKVLHGEQYLELYKPLP 418
LKF+YE + +F+ LPTF ++ G ++MG L I + + +LHGEQY+EL++
Sbjct: 347 LKFLYENNPEFAVLPTFFILPGLLAVMGSSLTASAIKHTTFDLTNILHGEQYIELFEAPA 406
Query: 419 RAGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGKRTSDK 477
G L + V DV+DK SG ++I SY E L+ NQ S F+VG+G F GK +
Sbjct: 407 TEGVLTTTSTVLDVVDKKSGALVITQSDSYDEQGTLVARNQSSTFVVGAGNFNGKTKAGP 466
Query: 478 -VKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCT 536
VK V P R PDA + T NQAA+YRLSGD NP+HIDP+F+++AG+ PILHGLCT
Sbjct: 467 EVKPLVPNPKRSPDASVEVPTHQNQAAVYRLSGDLNPMHIDPSFSAIAGYKVPILHGLCT 526
Query: 537 FGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKE-GNRIHFQTKVQETGD 595
G S + VL+QF +D + F+A K RF+KPV PGQTL+ +MWKE NR+ F+T V ET
Sbjct: 527 MGVSVKAVLKQFGGDDPTLFRAAKVRFSKPVLPGQTLRVDMWKEPNNRVCFRTVVVETST 586
Query: 596 IVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHIT 655
V+S AYVD T + LQS VF I R+ + K +NAVF + IT
Sbjct: 587 EVLSGAYVDFKQIVIKPNMTAAV--DLQSDAVFAGIKDRVAE-NEAKAKAINAVFLYKIT 643
Query: 656 KGGNIGAKWTIDLKSGSGKVYQGPAK--GAADTTIILSDEDFMEVVLGKLDPQKAFFSGR 713
GG + +W +DLK+ KVY+GP + G ADTT+ ++D D +E+ LGKL PQ AF G+
Sbjct: 644 SGGKVAKEWVLDLKNA--KVYEGPVQGGGKADTTMTIADGDMIELALGKLQPQTAFMKGK 701
Query: 714 LKARGNIMLSQKLQMILKDYAKL 736
LK GNIML+QKL +LK AKL
Sbjct: 702 LKIAGNIMLAQKLAPLLKTEAKL 724
>ref|XP_786662.2| PREDICTED: similar to 17-beta-hydroxysteroid dehydrogenase type 4
[Strongylocentrotus purpuratus]
ref|XP_001188817.1| PREDICTED: similar to 17-beta-hydroxysteroid dehydrogenase type 4
[Strongylocentrotus purpuratus]
Length = 696
Score = 972 bits (2514), Expect = 0.0, Method: Composition-based stats.
Identities = 396/740 (53%), Positives = 500/740 (67%), Gaps = 52/740 (7%)
Query: 1 MGSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVE 60
MG LRFDGRV LVTGAG GLG+ YAL A RGA VVVNDLGGD G GK S+AAD+VV
Sbjct: 1 MGEELRFDGRVALVTGAGGGLGKEYALLLAARGASVVVNDLGGDRAGQGKSSMAADQVVN 60
Query: 61 EIRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIH 120
EIR +GG AVANYDSVE+G+K+V+TALD FGRID+V+NNAGILRDRSFARISD DWD++H
Sbjct: 61 EIRSKGGNAVANYDSVEDGDKLVQTALDNFGRIDIVINNAGILRDRSFARISDMDWDLVH 120
Query: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAI 180
RVHLRGSF VTRAAW HMKKQK+GRIIMTSSA+G+YGNFGQ NYSAAKLGL+G++N+L+
Sbjct: 121 RVHLRGSFMVTRAAWPHMKKQKFGRIIMTSSAAGLYGNFGQTNYSAAKLGLVGMSNTLSR 180
Query: 181 EGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVG 240
EG K NI CNTIAP A SR+T+ +MP D+ E LKP+YVAP+V +L HE C+ GG++E G
Sbjct: 181 EGIKYNILCNTIAPMAASRLTEDIMPPDIFEKLKPDYVAPMVAYLSHEECQSTGGIYECG 240
Query: 241 AGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLS 300
AGW KLRW+RT G + + P T E S++ +L
Sbjct: 241 AGWAAKLRWQRTAGVNCLKPDQPYTAEQ------------------------NSMMFMLE 276
Query: 301 KIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKD 360
I+ EG A+ + + + VG S P
Sbjct: 277 SIN-EGSSEADSSPSSKGDTGGDGDDGGFNPV------------------VGVSTTQPDH 317
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGL-SINFAKVLHGEQYLELYKPLPR 419
LKF++E + DF LPTFGVI ++ L +PGL SI+ ++LHGEQYLEL KPL
Sbjct: 318 LKFLFELNEDFCVLPTFGVIPSFAALQ--NLTSVPGLESIDVTRILHGEQYLELKKPLDT 375
Query: 420 AGKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGKRTSDKV 478
+ KL + +V D++DK SG VII++ SY E EL+ NQ +FLVG+GGFGGKR+S +
Sbjct: 376 SAKLTNKPMVVDIVDKKSGAVIIINANSYDENNELVIVNQNVVFLVGAGGFGGKRSSPHL 435
Query: 479 KVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFG 538
K P+R PDA L + TSL+QAALYRLSGD+NPLHIDP+FA++ GF +PILHGLC+FG
Sbjct: 436 KETAKAPSRAPDASLQEKTSLDQAALYRLSGDYNPLHIDPSFAAMGGFAQPILHGLCSFG 495
Query: 539 FSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVI 598
F++R VL+Q+A+NDVS+FKAIK RF+KPV PGQT+QT+MW+EG RIHFQ+KV ETG + I
Sbjct: 496 FASRHVLKQYANNDVSKFKAIKVRFSKPVLPGQTIQTDMWQEGTRIHFQSKVVETGAVCI 555
Query: 599 SNAYVDLAPTSGTSAKTPSEGGK--LQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITK 656
S AYVDL + PS+ L+S +F + P +VKKVN V +++IT
Sbjct: 556 SGAYVDLHGVAEQKNAAPSQPSSSGLKSEAIFSAASGMVSGA-PVLVKKVNGVIQYNITS 614
Query: 657 GGNIGAKWTIDLKSGSGKVYQGPAK-GAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLK 715
G + WTIDLK G G VY G K G AD T+ +SDEDF+ + G L PQ AF SG++K
Sbjct: 615 DGKVAGVWTIDLK-GQGAVYVGEPKSGKADVTVTISDEDFVALASGSLKPQTAFLSGKIK 673
Query: 716 ARGNIMLSQKLQMILKDYAK 735
+G IML QK+ + + + K
Sbjct: 674 VKGQIMLLQKVLPMFESFMK 693
>ref|XP_001743502.1| predicted protein [Monosiga brevicollis MX1]
gb|EDQ92216.1| predicted protein [Monosiga brevicollis MX1]
Length = 716
Score = 951 bits (2459), Expect = 0.0, Method: Composition-based stats.
Identities = 366/740 (49%), Positives = 491/740 (66%), Gaps = 32/740 (4%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
S LRFD RVV+VTGAG GLGR YALAFA+RGA VVVNDLGG G G + AAD VV+E
Sbjct: 4 ASLLRFDERVVIVTGAGNGLGREYALAFAKRGARVVVNDLGGSVSGDGSSNRAADTVVDE 63
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR GG AVANYDSV G+ VV TA+ AFGR+DVVVNNAGILRDRSF+++++ DWDI+H+
Sbjct: 64 IRAAGGTAVANYDSVVNGQAVVDTAIKAFGRVDVVVNNAGILRDRSFSKMTEGDWDIVHQ 123
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHL+GSF V+RAAW HM+KQKYGRIIMT+S +GIYGNFGQANYSAAKLGL+GL+N+LA E
Sbjct: 124 VHLKGSFAVSRAAWPHMRKQKYGRIIMTASTAGIYGNFGQANYSAAKLGLVGLSNTLAYE 183
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGA 241
G K NIHCN + P AGSR++ +VMPED A+KPEYVAP+VL+LCHESCE N G++E GA
Sbjct: 184 GAKYNIHCNALVPTAGSRLSASVMPEDYANAMKPEYVAPVVLFLCHESCEANRGVYETGA 243
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
GW+ L+W+RT GA ++ ++PE V+ W I DF A S
Sbjct: 244 GWVAALKWQRTEGAKLQSAESSISPEKVRDVWDSINDFATA-----------------ST 286
Query: 302 IDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIK-DPKD 360
+DS G ++ S + A+ + P SY + A +YAL VG + P++
Sbjct: 287 VDSMNGTASLAASPEANVQQFDRKQALSHRFPTTSYVVSPRNAALYALSVGCNPSAHPEE 346
Query: 361 LKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRA 420
L+++YEG S+F LPTF VI Q + +PGL N ++LHGEQ + +++PLP
Sbjct: 347 LRYVYEGHSEFGTLPTFAVIPAQ------VMTGLPGLRFNPMQLLHGEQSVTIHRPLPTE 400
Query: 421 GKLKCEAVVADVLDKGSGVVIIMDVYSYSE-KELICHNQFSLFLVGSGGFGGKRTSDKVK 479
GKL +A D+LDKG G + I+ V + +E EL+ N FSLF+ G G FGG T+D +
Sbjct: 401 GKLVSQASFVDILDKGRGALAILKVETRAEAGELLVTNVFSLFIRGLGNFGGPSTNDAIP 460
Query: 480 VAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGF 539
V +P P V ++ T N AALYRL+GD NPLHIDP A +AGF +PILHGLCT+G
Sbjct: 461 GNVPVPQGAPTHVFSEKTPTNLAALYRLTGDVNPLHIDPEMAKVAGFQQPILHGLCTYGT 520
Query: 540 SARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVIS 599
+AR V+ Q D SR ++ RFA PV+PG+TL+T MW +RIHFQT+V E ++V+S
Sbjct: 521 AARHVIAQCLGGDASRVHVVRGRFAAPVFPGETLETSMWVRSSRIHFQTRVVERDEVVLS 580
Query: 600 NAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGN 659
+ YVD+ P+S ++ S K + VFE R ++ E+V++VNAVF + +
Sbjct: 581 HGYVDIVPSSSSNPSA-SLPSKPEVVEVFE---RMQANLSQELVRQVNAVFTFALKSAQG 636
Query: 660 IGAKWTIDLKSGSGKVYQGPAK---GAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKA 716
++W +DLKSG+G ++ A+ DTT+ LS++DF+++ G+L+ +AF +LK
Sbjct: 637 SDSRWVVDLKSGAGAIHPPGAQLEGLKVDTTLKLSEDDFVKLARGQLNAMQAFMQNKLKV 696
Query: 717 RGNIMLSQKLQMILKDYAKL 736
GN+ML+QKL + + AKL
Sbjct: 697 SGNMMLAQKLSGLFQTQAKL 716
>gb|EDM14435.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_a [Rattus
norvegicus]
gb|EDM14437.1| hydroxysteroid (17-beta) dehydrogenase 4, isoform CRA_a [Rattus
norvegicus]
Length = 582
Score = 892 bits (2305), Expect = 0.0, Method: Composition-based stats.
Identities = 480/563 (85%), Positives = 524/563 (93%), Gaps = 1/563 (0%)
Query: 145 RIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTV 204
RIIMT+SASGIYGNFGQANYSAAKLGLLGLAN+L IEGRK+NIHCNTIAPNAGSRMT+TV
Sbjct: 19 RIIMTASASGIYGNFGQANYSAAKLGLLGLANTLVIEGRKNNIHCNTIAPNAGSRMTETV 78
Query: 205 MPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPM 264
MPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVR++N PM
Sbjct: 79 MPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRKRNQPM 138
Query: 265 TPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGF 324
TPEAV+ NW KICDF NASKP+SIQESTG IIEVL KIDSEG +S NHT + S SGF
Sbjct: 139 TPEAVRDNWVKICDFSNASKPKSIQESTGGIIEVLHKIDSEG-ISQNHTGQVASADASGF 197
Query: 325 AGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQK 384
AG +G KLP FS +YTEL+ IMYALGVGAS+K+PKDLKF+YEGS+DFSCLPTFGVI+ QK
Sbjct: 198 AGVVGHKLPSFSSSYTELQCIMYALGVGASVKNPKDLKFVYEGSADFSCLPTFGVIVAQK 257
Query: 385 SMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMD 444
S+M GGLAE+PGLSINFAKVLHGEQYLELYKPLPR+G+LKCEAV+AD+LDKGSG+VI+MD
Sbjct: 258 SLMSGGLAEVPGLSINFAKVLHGEQYLELYKPLPRSGELKCEAVIADILDKGSGIVIVMD 317
Query: 445 VYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAAL 504
VYSYS KELIC+NQFS+F+VGSGGFGGKRTS+K+K AVA+P+RPPDAVL DTTSLNQAAL
Sbjct: 318 VYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAAVAVPSRPPDAVLRDTTSLNQAAL 377
Query: 505 YRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFA 564
YRLSGD NPLHIDP+FAS+AGF+KPILHGLCTFGFSAR VLQQFADNDVSRFKAIK RFA
Sbjct: 378 YRLSGDSNPLHIDPSFASIAGFEKPILHGLCTFGFSARHVLQQFADNDVSRFKAIKVRFA 437
Query: 565 KPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQS 624
KPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDL PTSG SA+TPSEGG LQS
Sbjct: 438 KPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLVPTSGVSAQTPSEGGALQS 497
Query: 625 TFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAA 684
VF EIGRRLKD+G EVVKKVNAVFEWHITK GN+ AKWTIDLK+GSG+VYQGPAKG+A
Sbjct: 498 ALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVAAKWTIDLKNGSGEVYQGPAKGSA 557
Query: 685 DTTIILSDEDFMEVVLGKLDPQK 707
DTTI +SDEDFMEVVLGKL+PQ
Sbjct: 558 DTTITISDEDFMEVVLGKLNPQN 580
>ref|XP_001400728.1| hypothetical protein An14g00990 [Aspergillus niger]
emb|CAK41898.1| unnamed protein product [Aspergillus niger]
Length = 901
Score = 831 bits (2148), Expect = 0.0, Method: Composition-based stats.
Identities = 282/623 (45%), Positives = 384/623 (61%), Gaps = 40/623 (6%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
G F G+V LVTG G GLGRAY L FA+ GA VVVNDL + + VV+E
Sbjct: 306 GEEPNFKGKVALVTGGGNGLGRAYCLLFAKYGASVVVNDL-----------VDPEPVVQE 354
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
I++ GG+AV N S E+GE VVKTA+DAFGRID+++NNAGILRD++F ++D+ W+ +
Sbjct: 355 IKKMGGQAVGNKASCEDGENVVKTAIDAFGRIDILINNAGILRDKAFTNMNDDLWNPVLN 414
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHLRG+++VT+AAW +M KQKYGRI+ T+S SGIYGNFGQANY+AAKLG+LG + +LA+E
Sbjct: 415 VHLRGTYKVTKAAWPYMLKQKYGRIVNTASTSGIYGNFGQANYAAAKLGILGFSRTLALE 474
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEE--NGGLFEV 239
G K NI NTIAPNAG+ MT+T+MPE++V+A KP+YVAPLV LC + E GL+E
Sbjct: 475 GAKYNIKVNTIAPNAGTNMTRTIMPEEMVQAFKPDYVAPLVALLCSDIVPEPSTKGLYEC 534
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN--ASKPQSIQESTGSIIE 297
G+GW G+ RW+RT G + +TPE V NWKKI +F++ A P+ Q + I+
Sbjct: 535 GSGWFGRTRWQRTGGHGFP-VDVKLTPEEVLKNWKKITNFDDGRADHPEDGQAGSEKIMA 593
Query: 298 VLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
+S S + A S+ Y + + I+Y L +GA
Sbjct: 594 NMSNRSGGD-------SEGGNKILQAIEKAKQATTDGTSFDYEDRDVILYNLSLGAK--- 643
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYK-P 416
DL +YE + F LPT+GVI + + EI + + +LHGEQY+E+ K P
Sbjct: 644 RTDLPLVYENNEHFQALPTYGVIPWFNTANPWNMDEIVA-NFSPMMLLHGEQYMEIRKFP 702
Query: 417 LPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYS--EKELICHNQFSLFLVGSGGFGG--K 472
+P A K + DV+DKG+ +++ + E + +N+ ++F+ GSGGFGG K
Sbjct: 703 IPTAAKTLTYPKLIDVVDKGNAALVVSGYTTKDAKTGEDLFYNESTVFIRGSGGFGGSPK 762
Query: 473 RTSDKVKVAVA---IPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKP 529
T+ + K AVA P R PDAV+ + TS +QAALYRL+GD NPLHIDP F+ + GF P
Sbjct: 763 PTARRPKAAVASYKAPQRKPDAVVEEKTSEDQAALYRLNGDRNPLHIDPEFSKVGGFKTP 822
Query: 530 ILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK 589
ILHGLC+ G S + V + FK +K RF+ V PGQTL+TEMWKEGN + FQT
Sbjct: 823 ILHGLCSLGVSGKHVFSTYG-----AFKNLKVRFSGVVLPGQTLRTEMWKEGNVVLFQTT 877
Query: 590 VQETGDIVISNAYVDLAPTSGTS 612
V +TG I+ A +L +
Sbjct: 878 VVDTGKPAITGAGAELLEGAKAK 900
Score = 432 bits (1111), Expect = e-119, Method: Composition-based stats.
Identities = 171/316 (54%), Positives = 218/316 (68%), Gaps = 2/316 (0%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
S LRFD + V+VTGAG GLG+AYAL FA RGA VVVNDLGG G GK + AAD VVEEI
Sbjct: 2 SELRFDNQTVVVTGAGGGLGKAYALFFASRGANVVVNDLGGSHSGEGKSAKAADVVVEEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R GGKAVANYDSVE GE +++TA+ FGRIDV++NNAGILRD SF + D+DWD+I+RV
Sbjct: 62 RAAGGKAVANYDSVENGEAIIETAIKNFGRIDVLLNNAGILRDISFKNMKDQDWDLIYRV 121
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
H G+++ RAAW H +KQKYGRII T+S++G++G+FGQANYSAAKLG +G +LA EG
Sbjct: 122 HTYGAYKCARAAWPHFRKQKYGRIINTASSAGLFGSFGQANYSAAKLGQVGFTETLAKEG 181
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESC-EENGGLFEVGA 241
K NI N IAP A SRMT TVMP +++E LKP++V PLV L H S E GG++EVG
Sbjct: 182 AKYNIIANVIAPIAASRMTATVMPPEVLENLKPDWVVPLVAALVHSSNTTETGGIYEVGG 241
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
G + KLRWER GA+++ + +TP A+ W + DF P + G + + L
Sbjct: 242 GHVAKLRWERAKGALLKT-DASLTPGAIARKWNDVNDFSQPDYPTGPADFMGLLEDGLKL 300
Query: 302 IDSEGGVSANHTSRAT 317
++ G N +
Sbjct: 301 PSAQAGEEPNFKGKVA 316
>ref|XP_746577.1| peroxisomal multifunctional beta-oxidation protein (MFP), putative
[Aspergillus fumigatus Af293]
gb|EAL84539.1| peroxisomal multifunctional beta-oxidation protein (MFP), putative
[Aspergillus fumigatus Af293]
gb|EDP47311.1| peroxisomal multifunctional beta-oxidation protein (MFP), putative
[Aspergillus fumigatus A1163]
Length = 899
Score = 830 bits (2144), Expect = 0.0, Method: Composition-based stats.
Identities = 282/623 (45%), Positives = 381/623 (61%), Gaps = 42/623 (6%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
G G+V LVTG G GLGR+Y L FA+ GA VVVNDL + + VV+E
Sbjct: 306 GEEPDLKGKVALVTGGGNGLGRSYCLLFAKLGASVVVNDL-----------VDPEPVVQE 354
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
I++ GGKAV N S E+G+ VVKTA+DAFGRID++VNNAGILRD++F ++D+ W+ +
Sbjct: 355 IKKMGGKAVGNKASCEDGDAVVKTAIDAFGRIDILVNNAGILRDKAFTNMNDDLWNAVIN 414
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHLRG+++VT+AAW HM KQKYGRI+ T+S SGIYGNFGQANY+AAKLG+LG + +LAIE
Sbjct: 415 VHLRGTYKVTKAAWPHMLKQKYGRIVNTTSTSGIYGNFGQANYAAAKLGILGFSRALAIE 474
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEE--NGGLFEV 239
G K NI NTIAPNAG+ MT+T+MPE++V+A KP+YVAP+V LC + C E + GL+E
Sbjct: 475 GAKYNIKVNTIAPNAGTNMTRTIMPEEMVQAFKPDYVAPMVALLCSDMCPEPSSKGLYEC 534
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN--ASKPQSIQESTGSIIE 297
G+GW RW+R+ G + +TPE V NWK+I DF++ A PQ Q T ++
Sbjct: 535 GSGWFSSTRWQRSGGHGFP-VDVKLTPETVLKNWKQITDFDDGRADHPQDSQAGTEKVMA 593
Query: 298 VLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
+S G + + A ++ Y + + I+Y L VGA
Sbjct: 594 NMSNRSGGEG---------GNNILANIEKAKQATTEGTAFDYIDRDIILYNLSVGAK--- 641
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYK-P 416
DL +YE + F LPTFGVI + + +I + + +LHGEQY+E+ K P
Sbjct: 642 RTDLPLVYENNEHFQALPTFGVIPWFNTATPWNMDDIVA-NFSPMMLLHGEQYMEIRKFP 700
Query: 417 LPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYS--EKELICHNQFSLFLVGSGGFGG--K 472
+P K + DV+DKG +++ + E + +N+ ++F+ GSGGFGG K
Sbjct: 701 IPTEAKTLTYPKLIDVVDKGKAALVVAGYTTKDAKTGEDLFYNESTVFIRGSGGFGGSPK 760
Query: 473 RTSDKVKVAVA---IPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKP 529
T+ + K A A P R PD V+ + TS +QAALYRL+GD NPLHIDP F+ + GF P
Sbjct: 761 PTASRPKGATAAYNPPKRQPDVVIEEKTSEDQAALYRLNGDRNPLHIDPEFSKVGGFKTP 820
Query: 530 ILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK 589
ILHGLC+ G S + V +F FK++K RFA V PGQTL+TEMWKEGN + FQT
Sbjct: 821 ILHGLCSLGISGKHVFNKFG-----AFKSLKVRFAGVVLPGQTLKTEMWKEGNTVIFQTT 875
Query: 590 VQETGDIVISNAYVDLAPTSGTS 612
V ETG I A +L +
Sbjct: 876 VVETGKPAILGAGAELLEGAKAK 898
Score = 421 bits (1083), Expect = e-115, Method: Composition-based stats.
Identities = 168/311 (54%), Positives = 213/311 (68%), Gaps = 3/311 (0%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
S LRFD + V+VTGAG GLG+AYA FA RGA VVVNDLG G G S AAD VVEEI
Sbjct: 2 SELRFDNQTVVVTGAGGGLGKAYATFFASRGANVVVNDLGVSHSGEGASSKAADVVVEEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R GGKAVANYDSVE GE +++TA+ FGRIDV++NNAGILRD SF + D+DWD+I++V
Sbjct: 62 RAAGGKAVANYDSVENGEAIIETAIKNFGRIDVLINNAGILRDVSFKNMKDQDWDLINKV 121
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
H G+++ RAAW H +KQKYGRII T+SA+G++GNFGQANYSAAKLG +G +LA EG
Sbjct: 122 HTYGAYKCARAAWPHFRKQKYGRIINTASAAGLFGNFGQANYSAAKLGQVGFTETLAKEG 181
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESC-EENGGLFEVGA 241
K NI N IAP A SRMT T+MP +++E LKP++V PLV L H S E+G +FEVG
Sbjct: 182 AKYNIIANVIAPIAASRMTATIMPPEVLENLKPDWVVPLVAVLVHPSNTTESGSIFEVGG 241
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
G + KLRWER GA+++ + +TP A+ WK + D+ P + +++E K
Sbjct: 242 GHMAKLRWERAKGALLKT-DASLTPGAIARKWKDVYDYSQPEYPIGPAD-FMTLLENGMK 299
Query: 302 IDSEGGVSANH 312
S
Sbjct: 300 TPSAPAGEEPD 310
>ref|XP_001262415.1| peroxisomal multifunctional beta-oxidation protein (MFP), putative
[Neosartorya fischeri NRRL 181]
gb|EAW20518.1| peroxisomal multifunctional beta-oxidation protein (MFP), putative
[Neosartorya fischeri NRRL 181]
Length = 899
Score = 827 bits (2138), Expect = 0.0, Method: Composition-based stats.
Identities = 283/623 (45%), Positives = 382/623 (61%), Gaps = 42/623 (6%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
G G+V LVTG G GLGR+Y L FA+ GA VVVNDL + + VV+E
Sbjct: 306 GEEPDLKGKVALVTGGGNGLGRSYCLLFAKLGASVVVNDL-----------VDPEPVVQE 354
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
I++ GGKAV N S E+G+ VVKTA+DAFGRID++VNNAGILRD++F ++D+ W+ +
Sbjct: 355 IKKMGGKAVGNKASCEDGDAVVKTAIDAFGRIDILVNNAGILRDKAFTNMNDDLWNAVIH 414
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHLRG+++VT+AAW HM KQKYGRI+ T+S SGIYGNFGQANY+AAKLG+LGL+ +LAIE
Sbjct: 415 VHLRGTYKVTKAAWPHMLKQKYGRIVNTASTSGIYGNFGQANYAAAKLGILGLSRALAIE 474
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEE--NGGLFEV 239
G K NI NTIAPNAG+ MT+T+MPE++V+A KP+YVAP+V LC + C E + GL+E
Sbjct: 475 GAKYNIKVNTIAPNAGTNMTRTIMPEEMVQAFKPDYVAPMVALLCSDMCPEPSSKGLYEC 534
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN--ASKPQSIQESTGSIIE 297
G+GW RW+R+ G + +TPEAV NWK+I DF++ A P+ Q T ++
Sbjct: 535 GSGWFSSTRWQRSGGHGFP-VDVKLTPEAVLKNWKQITDFDDGRADHPEDSQAGTEKVMA 593
Query: 298 VLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
+S G + + A ++ Y + + I+Y L VGA
Sbjct: 594 NMSNRSGGEG---------GNDILANIEKAKQATTEGTAFDYVDRDVILYNLSVGAK--- 641
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYK-P 416
DL +YE + F LPTFGVI + + +I + + +LHGEQY+E+ K P
Sbjct: 642 RTDLPLVYENNEHFQALPTFGVIPWFNTATPWNMDDIVA-NFSPMMLLHGEQYMEVRKFP 700
Query: 417 LPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYS--EKELICHNQFSLFLVGSGGFGG--K 472
+P K + DV+DKG +++ + E + +N+ ++F+ GSGGFGG K
Sbjct: 701 IPTEAKTLTYPKLIDVVDKGKAALVVAGYTTKDAKTGEDLFYNESTVFIRGSGGFGGSPK 760
Query: 473 RTSDKVKVAVA---IPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKP 529
T+ + K A A P R PD V+ + TS +QAALYRL+GD NPLHIDP F+ + GF P
Sbjct: 761 PTAPRPKGATAAYNPPKRQPDVVIEEKTSEDQAALYRLNGDRNPLHIDPEFSKVGGFKTP 820
Query: 530 ILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK 589
ILHGLC+ G S + V +F FK +K RFA V PGQTL+TEMWKEGN + FQT
Sbjct: 821 ILHGLCSLGVSGKHVFNKFG-----AFKNLKVRFAGVVLPGQTLKTEMWKEGNTVIFQTT 875
Query: 590 VQETGDIVISNAYVDLAPTSGTS 612
V ETG I A +L +
Sbjct: 876 VVETGKPAILGAGAELLEGAKAK 898
Score = 422 bits (1086), Expect = e-116, Method: Composition-based stats.
Identities = 168/303 (55%), Positives = 213/303 (70%), Gaps = 3/303 (0%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
S LRFD + V+VTGAG GLG+AYA FA RGA VVVNDLG G G S AAD VVEEI
Sbjct: 2 SELRFDNQTVVVTGAGGGLGKAYATFFASRGANVVVNDLGVSHSGEGASSKAADVVVEEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R GGKAVANYDSVE GE +++TA+ FGRIDV++NNAGILRD SF + D+DWD+I++V
Sbjct: 62 RAAGGKAVANYDSVENGEAIIETAIKNFGRIDVLINNAGILRDVSFKNMKDQDWDLINKV 121
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
H G+++ RAAW H +KQKYGRII T+SA+G++GNFGQANYSAAKLG +G +LA EG
Sbjct: 122 HTYGAYKCARAAWPHFRKQKYGRIINTASAAGLFGNFGQANYSAAKLGQVGFTETLAKEG 181
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESC-EENGGLFEVGA 241
K NI N IAP A SRMT T+MP +++E LKP+++ PLV L H S E+G +FEVG
Sbjct: 182 AKYNIIANVIAPIAASRMTATIMPPEVLENLKPDWIVPLVAVLVHPSNTTESGSIFEVGG 241
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
G + KLRWER GA+++ + +TP A+ WK + D+ P + S++E K
Sbjct: 242 GHMAKLRWERAKGALLKT-DASLTPGAIARKWKDVYDYSQPEYPTGPAD-FMSLLENGMK 299
Query: 302 IDS 304
S
Sbjct: 300 TPS 302
>ref|XP_001211399.1| acetoacetyl-CoA reductase [Aspergillus terreus NIH2624]
gb|EAU37183.1| acetoacetyl-CoA reductase [Aspergillus terreus NIH2624]
Length = 893
Score = 823 bits (2126), Expect = 0.0, Method: Composition-based stats.
Identities = 274/623 (43%), Positives = 376/623 (60%), Gaps = 40/623 (6%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
G F G+V LVTG G GLGR+Y L FA+ GA VVVNDL + + VV+E
Sbjct: 298 GQEPDFKGKVALVTGGGNGLGRSYCLLFAKYGASVVVNDL-----------VDPEPVVQE 346
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
IR+ GGKAV N S E+G+ V+KTA+DAFGRID++VNNAGILRD++F ++D+ W+ +
Sbjct: 347 IRQMGGKAVGNKASCEDGDAVIKTAIDAFGRIDILVNNAGILRDKAFTNMNDDLWNPVIN 406
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHLRG+++VT+AAW +M KQKYGRII T+S SGIYGNFGQANY+AAKLG+LG + +LA+E
Sbjct: 407 VHLRGTYKVTKAAWPYMLKQKYGRIINTASTSGIYGNFGQANYAAAKLGILGFSRTLALE 466
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEE--NGGLFEV 239
G K NI NTIAPNAG+ MT+T+MPE++V+A KP+YVAPLV+ L + E GLFE
Sbjct: 467 GAKYNIKVNTIAPNAGTNMTRTIMPEEMVQAFKPDYVAPLVVLLGSDMAPEPSTKGLFEC 526
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN--ASKPQSIQESTGSIIE 297
G+GW + RW+RT G + +TPE V +W I +F++ A P+ Q T ++
Sbjct: 527 GSGWFARTRWQRTGGHGFP-VDVKLTPEEVLKHWNDIANFDDGRADHPEDGQAGTEKVMA 585
Query: 298 VLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
++ A + + A K + Y + + I+Y L +GA
Sbjct: 586 NMANR-------AGGAEEGGNDILANIEKAKQAKSDGTPFDYVDRDIILYNLSLGAK--- 635
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYK-P 416
DL +YE + F LPT+GVI + + +I + + +LHGEQY+E+ K P
Sbjct: 636 RTDLPLVYENNEHFQALPTYGVIPWFNTATPWNMDDIVK-NFSPMMLLHGEQYMEIRKFP 694
Query: 417 LPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYS--EKELICHNQFSLFLVGSGGFGGKRT 474
+P A + DV+DKG+ +++ + E + +N+ ++F+ GSGGFGG
Sbjct: 695 IPTAANTVTYPKLIDVVDKGNAALVVAGYTTKDAKTGEDLFYNESTVFIRGSGGFGGSPK 754
Query: 475 SDKVKVAV-----AIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKP 529
+ P R PDAV+ + TS +QAALYRL+GD NPLHIDP F+ + GF P
Sbjct: 755 PTAARPKAATAAYKPPKRQPDAVIEEKTSEDQAALYRLNGDRNPLHIDPEFSKVGGFKTP 814
Query: 530 ILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK 589
ILHGLC+ G S + V +F FK +K RFA V PGQTL+TEMWKEGN + FQT
Sbjct: 815 ILHGLCSLGVSGKHVFTKFG-----AFKNLKVRFAGVVLPGQTLKTEMWKEGNTVLFQTT 869
Query: 590 VQETGDIVISNAYVDLAPTSGTS 612
V ETG I+ A V+L +
Sbjct: 870 VVETGKPAITGAGVELLEGAKAK 892
Score = 408 bits (1051), Expect = e-112, Method: Composition-based stats.
Identities = 167/316 (52%), Positives = 213/316 (67%), Gaps = 10/316 (3%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
S LRFD + V+VTGAG GLG+AYA FA RGA VVVNDLG KG GK S AAD VVEEI
Sbjct: 2 SELRFDNQTVVVTGAGGGLGKAYATFFASRGANVVVNDLGASHKGEGKSSKAADVVVEEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R GGKAVANYDSVE GE ++ TA+ +FGR+D+++NNAGILRD SF + DEDWD+I++
Sbjct: 62 RAAGGKAVANYDSVENGEAIIDTAIKSFGRVDILINNAGILRDISFKNMKDEDWDLINK- 120
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
RAAW H +KQKYGR+I T+SA+G++G+FGQANYSAAKLG +G +LA EG
Sbjct: 121 -------CARAAWPHFRKQKYGRVINTASAAGLFGSFGQANYSAAKLGQVGFTETLAKEG 173
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESC-EENGGLFEVGA 241
K NI N IAP A SRMT TVMP +++E LKPE+V PLV LCH S E+GG++EVG
Sbjct: 174 AKYNIIANVIAPIAASRMTATVMPPEVLENLKPEWVVPLVAVLCHSSNTTESGGIYEVGG 233
Query: 242 GWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSK 301
G + KLRWER GA+++ + +TP A+ W + DF S P + + + L
Sbjct: 234 GHVAKLRWERAKGALLKT-DASLTPGAIARKWNDVNDFSAPSYPTGPADFMSLLEDGLKT 292
Query: 302 IDSEGGVSANHTSRAT 317
++ G + +
Sbjct: 293 PSAQAGQEPDFKGKVA 308
>ref|XP_001241529.1| hypothetical protein CIMG_08692 [Coccidioides immitis RS]
gb|EAS29946.1| hypothetical protein CIMG_08692 [Coccidioides immitis RS]
Length = 904
Score = 821 bits (2123), Expect = 0.0, Method: Composition-based stats.
Identities = 287/623 (46%), Positives = 381/623 (61%), Gaps = 36/623 (5%)
Query: 2 GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEE 61
F G+V L+TGAG GLGRAYAL FA+ GA VVVNDL + + VV+E
Sbjct: 305 AKQPDFTGKVALITGAGNGLGRAYALLFAKLGAAVVVNDL-----------VDPEPVVQE 353
Query: 62 IRRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHR 121
I++ GGKAV + SVE+G VVK A+DAFGRID++VNNAGILRD++F + D W+ I
Sbjct: 354 IKQMGGKAVGSKASVEDGAAVVKPAIDAFGRIDILVNNAGILRDKAFTNMDDSLWNPIIN 413
Query: 122 VHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
VHLRG++ VT+AAW +M KQKYGRI+ T+S SGIYGNFGQANY+AAKLG+LG + +LA+E
Sbjct: 414 VHLRGTYSVTKAAWPYMLKQKYGRIVNTTSTSGIYGNFGQANYAAAKLGILGFSRALALE 473
Query: 182 GRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESC--EENGGLFEV 239
G K NI NTIAPNAG++MT+TVMPE++V+A KP+ VAP+V LC + GL+E
Sbjct: 474 GAKYNILVNTIAPNAGTQMTRTVMPEEVVQAFKPDQVAPIVALLCSDMVPQPATKGLYEC 533
Query: 240 GAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFEN--ASKPQSIQESTGSIIE 297
G+GW G+ RW+R+ G + +TPEAV A W KI +F++ A P+ Q SI+E
Sbjct: 534 GSGWFGRTRWQRSGGHGFPI-DVELTPEAVAAMWSKITNFDDGRADHPEDGQAGFKSIME 592
Query: 298 VLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKD 357
+S SA S A G K S+ YT+ + I+Y + +GA
Sbjct: 593 NMSNRSGG---SAAKGSDENQQILDAITAAKGMKAEGTSFDYTDRDVILYNVSLGAK--- 646
Query: 358 PKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYK-P 416
L +YE +F LPTFGV+ + + + EI + + +LHGEQYLE+ K P
Sbjct: 647 RTQLPLVYENDDNFQPLPTFGVVPWFNTDIPWNMGEIVA-NFSPMMLLHGEQYLEIKKFP 705
Query: 417 LPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYS--EKELICHNQFSLFLVGSGGFGGK-- 472
+P A K + DV+DKG+ +++ + E + +N+ ++F+ GSGGFGG
Sbjct: 706 IPTAAKTISYPKLIDVVDKGNAAIVVNGYITKDANTGEDLFYNESTMFIRGSGGFGGPSK 765
Query: 473 ---RTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKP 529
R A P R PDAV+ + TS +QAALYRL+GD NPLHIDP F+ + GF P
Sbjct: 766 PTARRPAGATAAYKPPQRKPDAVIEEKTSEDQAALYRLNGDRNPLHIDPEFSKVGGFKIP 825
Query: 530 ILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTK 589
ILHGLC+ G S + V +F FK IK RFA V PGQTL+TEMWKEGN + FQT
Sbjct: 826 ILHGLCSMGISGKHVFSKFG-----AFKNIKVRFAGVVLPGQTLRTEMWKEGNFVLFQTT 880
Query: 590 VQETGDIVISNAYVDLAPTSGTS 612
V ETG I+ A V+L +
Sbjct: 881 VVETGKPAIAGAGVELVSDKASK 903
Score = 429 bits (1105), Expect = e-118, Method: Composition-based stats.
Identities = 172/328 (52%), Positives = 227/328 (69%), Gaps = 2/328 (0%)
Query: 3 SPLRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEI 62
S LRFDG+ V+VTGAG GLG+AYA+ F RGA VVVNDLGG G G S AAD VV+EI
Sbjct: 2 SQLRFDGQTVVVTGAGGGLGKAYAVFFGSRGANVVVNDLGGSHTGEGHSSKAADVVVDEI 61
Query: 63 RRRGGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRV 122
R +GGKAVANYDSVE GEK+++TA+ FGRID+++NNAGILRD SF + D+DWD+I++V
Sbjct: 62 RSKGGKAVANYDSVEFGEKIIETAIKNFGRIDILINNAGILRDVSFKNMKDQDWDLINQV 121
Query: 123 HLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEG 182
H GS++ +RAAW + +KQK+GR+I T+SA+G++GNFGQ NYSAAKL L+G +LA EG
Sbjct: 122 HTYGSYKCSRAAWPYFRKQKFGRVINTASAAGLFGNFGQTNYSAAKLALVGFTETLAKEG 181
Query: 183 RKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAG 242
K NIH N IAP A SRMT+TVMP +++E LKPE+V PLV +L H SC+E G +FE GAG
Sbjct: 182 IKYNIHANVIAPIAASRMTETVMPPEVLENLKPEWVVPLVAFLVHSSCKETGSIFEAGAG 241
Query: 243 WIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKI 302
+ KLRWER GA+++ + +TP A+ A W ++ +F S P + ++E K+
Sbjct: 242 HVAKLRWERAKGALLKT-DDSLTPGALLAKWDQVNNFSEPSYPTGPND-FMDLLEEGMKL 299
Query: 303 DSEGGVSANHTSRATSTATSGFAGAIGQ 330
S + + T G
Sbjct: 300 PSSPAAKQPDFTGKVALITGAGNGLGRA 327
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.313 0.185 0.598
Lambda K H
0.267 0.0567 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,228,026,668
Number of Sequences: 6899187
Number of extensions: 904737952
Number of successful extensions: 2621451
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 67894
Number of HSP's successfully gapped in prelim test: 26384
Number of HSP's that attempted gapping in prelim test: 2309167
Number of HSP's gapped (non-prelim): 122057
length of query: 736
length of database: 2,350,152,223
effective HSP length: 142
effective length of query: 594
effective length of database: 1,370,467,669
effective search space: 814057795386
effective search space used: 814057795386
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 84 (36.5 bits)