BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= ENSG00000138413__[Homo_sapiens]
(414 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_005887.2| isocitrate dehydrogenase 1 (NADP+), solubl... 856 0.0
gb|AAH93020.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 855 0.0
emb|CAG38738.1| IDH1 [Homo sapiens] 855 0.0
emb|CAB66637.1| hypothetical protein [Homo sapiens] >gi|117... 852 0.0
ref|XP_001141655.1| PREDICTED: isocitrate dehydrogenase 1 (... 852 0.0
sp|Q5R9C5|IDHC_PONPY Isocitrate dehydrogenase [NADP] cytopl... 851 0.0
emb|CAD97653.1| hypothetical protein [Homo sapiens] >gi|117... 850 0.0
gb|AAD02918.1| NADP-dependent isocitrate dehydrogenase [Hom... 849 0.0
emb|CAG38553.1| IDH1 [Homo sapiens] 849 0.0
ref|XP_001107627.1| PREDICTED: isocitrate dehydrogenase 1 (... 848 0.0
emb|CAH91635.1| hypothetical protein [Pongo abelii] 848 0.0
emb|CAH89719.1| hypothetical protein [Pongo abelii] 846 0.0
ref|XP_850187.1| PREDICTED: similar to Isocitrate dehydroge... 836 0.0
ref|XP_001505172.1| PREDICTED: similar to Isocitrate dehydr... 835 0.0
ref|NP_113698.1| isocitrate dehydrogenase 1 (NADP+), solubl... 833 0.0
sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytopl... 830 0.0
sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytopl... 830 0.0
ref|NP_851355.2| isocitrate dehydrogenase 1 (NADP+), solubl... 827 0.0
gb|AAH88986.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 825 0.0
ref|NP_034627.3| isocitrate dehydrogenase 1 (NADP+), solubl... 825 0.0
dbj|BAE39644.1| unnamed protein product [Mus musculus] 825 0.0
sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytopl... 824 0.0
sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytopl... 824 0.0
ref|NP_001009276.1| cytosolic NADP-isocitrate dehydrogenase... 823 0.0
dbj|BAC39792.1| unnamed protein product [Mus musculus] 823 0.0
ref|XP_860821.1| PREDICTED: similar to Isocitrate dehydroge... 819 0.0
pdb|2CMJ|A Chain A, Crystal Structure Of Mouse Cytosolic Is... 817 0.0
ref|XP_860853.1| PREDICTED: similar to Isocitrate dehydroge... 816 0.0
ref|XP_001511049.1| PREDICTED: similar to cytosolic NADP-de... 789 0.0
ref|XP_001365492.1| PREDICTED: similar to cytosolic NADP-de... 787 0.0
gb|ABU41004.1| isocitrate dehydrogenase 1 [Anser anser] 785 0.0
ref|XP_421965.2| PREDICTED: similar to cytosolic NADP-depen... 784 0.0
ref|NP_001088022.1| hypothetical protein LOC494713 [Xenopus... 776 0.0
gb|ABD77215.1| isocitrate dehydrogenase 1 [Homo sapiens] 776 0.0
gb|ABD77209.1| isocitrate dehydrogenase 1 [Rattus norvegicus] 771 0.0
gb|ABD77216.1| isocitrate dehydrogenase 1 [Aotus trivirgatus] 768 0.0
gb|ABD77211.1| isocitrate dehydrogenase 1 [Cavia porcellus] 764 0.0
gb|ABD77208.1| isocitrate dehydrogenase 1 [Mus musculus] 763 0.0
gb|ABD77213.1| isocitrate dehydrogenase 1 [Oryctolagus cuni... 760 0.0
gb|ABD77217.1| isocitrate dehydrogenase 1 [Tupaia glis] 752 0.0
gb|ABD77222.1| isocitrate dehydrogenase 1 [Diceros bicornis] 749 0.0
gb|ABD77221.1| isocitrate dehydrogenase 1 [Ceratotherium si... 745 0.0
gb|ABD77205.1| isocitrate dehydrogenase 1 [Loxodonta africana] 744 0.0
gb|ABD77218.1| isocitrate dehydrogenase 1 [Felis catus] 743 0.0
gb|ABD77210.1| isocitrate dehydrogenase 1 [Mesocricetus aur... 743 0.0
gb|ABD77214.1| isocitrate dehydrogenase 1 [Tadarida brasili... 742 0.0
gb|ABD77223.1| isocitrate dehydrogenase 1 [Bos taurus] 740 0.0
gb|ABD77207.1| isocitrate dehydrogenase 1 [Tamandua tetrada... 739 0.0
gb|ABD77219.1| isocitrate dehydrogenase 1 [Canis familiaris] 738 0.0
gb|ABD77224.1| isocitrate dehydrogenase 1 [Balaenoptera phy... 737 0.0
emb|CAQ15240.1| isocitrate dehydrogenase 1 (NADP+), soluble... 737 0.0
gb|ABD77225.2| isocitrate dehydrogenase 1 [Hippopotamus amp... 737 0.0
ref|NP_958907.1| isocitrate dehydrogenase 1 (NADP+), solubl... 736 0.0
gb|ABD77206.1| isocitrate dehydrogenase 1 [Dasypus novemcin... 730 0.0
emb|CAG02627.1| unnamed protein product [Tetraodon nigrovir... 715 0.0
gb|AAI53922.1| Idh1 protein [Danio rerio] 695 0.0
gb|ABD77202.1| isocitrate dehydrogenase 1 [Monodelphis dome... 689 0.0
gb|ABD77203.1| isocitrate dehydrogenase 1 [Didelphis virgin... 687 0.0
ref|XP_968850.1| PREDICTED: similar to CG7176-PC, isoform C... 686 0.0
gb|ABD77212.1| isocitrate dehydrogenase 1 [Lepus europaeus] 686 0.0
ref|XP_001633903.1| predicted protein [Nematostella vectens... 683 0.0
ref|XP_001688948.1| AGAP006660-PA [Anopheles gambiae str. P... 683 0.0
gb|ABI52605.1| isocitrate dehydrogenase [Gryllus firmus] 681 0.0
gb|EAW55211.1| hCG15865, isoform CRA_a [Homo sapiens] 681 0.0
ref|XP_001841910.1| isocitrate dehydrogenase cytoplasmic [C... 671 0.0
gb|ACO14957.1| Isocitrate dehydrogenase cytoplasmic [Caligu... 667 0.0
ref|XP_001650675.1| nadp-specific isocitrate dehydrogenase ... 666 0.0
ref|NP_001040134.1| isocitrate dehydrogenase [Bombyx mori] ... 665 0.0
gb|ABD77226.1| isocitrate dehydrogenase 1 [Sus scrofa] 663 0.0
ref|XP_780121.1| PREDICTED: similar to cytosolic NADP-depen... 660 0.0
gb|ABD77204.1| isocitrate dehydrogenase 1 [Sminthopsis doug... 660 0.0
gb|ABD77220.1| isocitrate dehydrogenase 1 [Equus caballus] 657 0.0
ref|XP_001608101.1| PREDICTED: similar to isocitrate dehydr... 655 0.0
ref|XP_623673.2| PREDICTED: similar to Isocitrate dehydroge... 652 0.0
ref|XP_001670101.1| Hypothetical protein CBG21657 [Caenorha... 648 0.0
ref|NP_501665.1| F59B8.2 [Caenorhabditis elegans] >gi|38778... 645 0.0
ref|NP_729366.1| Isocitrate dehydrogenase CG7176-PB, isofor... 634 e-180
ref|NP_652044.1| Isocitrate dehydrogenase CG7176-PC, isofor... 632 e-179
ref|NP_729367.1| Isocitrate dehydrogenase CG7176-PD, isofor... 632 e-179
ref|NP_729368.1| Isocitrate dehydrogenase CG7176-PA, isofor... 632 e-179
ref|XP_001354101.1| GA20156-PA [Drosophila pseudoobscura] >... 631 e-179
ref|XP_970446.1| PREDICTED: similar to isocitrate dehydroge... 616 e-174
ref|XP_536192.2| PREDICTED: similar to isocitrate dehydroge... 609 e-172
ref|XP_001845030.1| isocitrate dehydrogenase [Culex pipiens... 608 e-172
ref|NP_001093090.1| NADPH-specific isocitrate dehydrogenase... 608 e-172
ref|XP_821599.1| isocitrate dehydrogenase, putative [Trypan... 607 e-172
ref|NP_786984.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 606 e-171
sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitoc... 606 e-171
ref|NP_766599.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 605 e-171
sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitoc... 605 e-171
emb|CAA49208.1| isocitrate dehydrogenase (NADP+) [Homo sapi... 603 e-171
ref|NP_001014183.1| isocitrate dehydrogenase 2 (NADP+), mit... 603 e-171
sp|P33198|IDHP_PIG Isocitrate dehydrogenase [NADP], mitocho... 603 e-171
pdb|1LWD|A Chain A, Crystal Structure Of Nadp-Dependent Iso... 603 e-171
ref|XP_510589.2| PREDICTED: isocitrate dehydrogenase 2 (NAD... 602 e-170
ref|XP_001095686.1| PREDICTED: isocitrate dehydrogenase 2 (... 602 e-170
ref|NP_002159.2| isocitrate dehydrogenase 2 (NADP+), mitoch... 602 e-170
gb|EAX02083.1| isocitrate dehydrogenase 2 (NADP+), mitochon... 602 e-170
ref|XP_001369305.1| PREDICTED: hypothetical protein [Monode... 601 e-170
ref|XP_312860.4| AGAP003168-PA [Anopheles gambiae str. PEST... 601 e-170
ref|NP_001026770.1| hypothetical protein LOC431056 [Gallus ... 600 e-170
dbj|BAD96636.1| isocitrate dehydrogenase 2 (NADP+), mitocho... 600 e-170
ref|XP_001168316.1| PREDICTED: isocitrate dehydrogenase 2 (... 600 e-170
ref|XP_860792.1| PREDICTED: similar to Isocitrate dehydroge... 596 e-168
emb|CAG13105.1| unnamed protein product [Tetraodon nigrovir... 596 e-168
ref|NP_970434.1| isocitrate dehydrogenase [Bdellovibrio bac... 595 e-168
ref|NP_955858.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 595 e-168
gb|ACO14046.1| Isocitrate dehydrogenase, mitochondrial prec... 593 e-168
ref|XP_001634205.1| predicted protein [Nematostella vectens... 593 e-168
ref|XP_001176537.1| PREDICTED: similar to Isocitrate dehydr... 593 e-167
gb|ABD36135.1| isocitrate dehydrogenase precursor [Bombyx m... 592 e-167
ref|XP_001168291.1| PREDICTED: isocitrate dehydrogenase 2 (... 592 e-167
gb|AAC64182.1| NADP-dependent isocitrate dehydrogenase [Gly... 592 e-167
gb|ABE98244.1| mitochondrial isocitrate dehydrogenase 2-lik... 591 e-167
gb|EEJ98364.1| isocitrate dehydrogenase (NADP) [Thermomonos... 588 e-166
ref|XP_001168261.1| PREDICTED: isocitrate dehydrogenase 2 (... 588 e-166
ref|YP_001296741.1| isocitrate dehydrogenase [Flavobacteriu... 588 e-166
gb|AAV33246.1| isocitrate dehydrogenase [Toxoplasma gondii] 587 e-166
ref|YP_001160602.1| isocitrate dehydrogenase [Salinispora t... 587 e-166
dbj|BAC77065.1| NADP-specific isocitrate dehydrogenase [Lup... 587 e-166
ref|XP_001462393.1| hypothetical protein GSPATT00027349001 ... 585 e-165
ref|YP_001538953.1| isocitrate dehydrogenase, NADP-dependen... 585 e-165
ref|XP_645283.1| isocitrate dehydrogenase (NADP+) [Dictyost... 585 e-165
gb|AAC52473.1| isocitrate dehydrogenase 585 e-165
prf||2211361A isocitrate dehydrogenase 585 e-165
gb|ABO93633.1| isocitrate dehydrogenase 2 [Toxoplasma gondii] 583 e-165
emb|CAG02362.1| unnamed protein product [Tetraodon nigrovir... 583 e-165
ref|NP_001004799.1| MGC69505 protein [Xenopus tropicalis] >... 583 e-164
ref|XP_001698704.1| isocitrate dehydrogenase, NADP-dependen... 583 e-164
ref|XP_828183.1| isocitrate dehydrogenase [Trypanosoma bruc... 582 e-164
emb|CAA73139.1| isocitrate dehydrogenase (NADP+) [Apium gra... 582 e-164
ref|XP_001454244.1| hypothetical protein GSPATT00020509001 ... 582 e-164
ref|NP_001043749.1| Os01g0654500 [Oryza sativa (japonica cu... 582 e-164
ref|NP_385898.1| isocitrate dehydrogenase [Sinorhizobium me... 581 e-164
gb|ABK24873.1| unknown [Picea sitchensis] 580 e-164
ref|NP_001056381.1| Os05g0573200 [Oryza sativa (japonica cu... 580 e-164
emb|CAA53300.1| isocitrate dehydrogenase (NADP+) [Solanum t... 580 e-163
ref|NP_698203.1| isocitrate dehydrogenase [Brucella suis 13... 579 e-163
ref|YP_677841.1| isocitrate dehydrogenase [Cytophaga hutchi... 579 e-163
ref|XP_001778805.1| predicted protein [Physcomitrella paten... 579 e-163
ref|YP_001327198.1| isocitrate dehydrogenase [Sinorhizobium... 578 e-163
gb|AAL11503.1|AF367443_1 NADP-dependent isocitrate dehydrog... 578 e-163
ref|NP_539708.1| isocitrate dehydrogenase [Brucella meliten... 577 e-163
dbj|BAA34112.1| NADP specific isocitrate dehydrogenase [Dau... 577 e-163
emb|CAA65503.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 577 e-163
gb|AAB39248.1| NADP-isocitrate dehydrogenase [Eucalyptus gl... 577 e-163
ref|NP_001042583.1| Os01g0248400 [Oryza sativa (japonica cu... 577 e-163
ref|NP_001080321.1| hypothetical protein LOC380013 [Xenopus... 577 e-163
gb|AAF73472.1|AF268076_1 NADP-dependent isocitrate dehydrog... 577 e-163
ref|NP_175836.1| ICDH; isocitrate dehydrogenase (NADP+) [Ar... 576 e-162
ref|XP_001457045.1| hypothetical protein GSPATT00022820001 ... 576 e-162
ref|XP_001837820.1| hypothetical protein CC1G_11465 [Coprin... 575 e-162
sp|P50217|IDHC_SOLTU Isocitrate dehydrogenase [NADP] (Oxalo... 575 e-162
ref|XP_001778590.1| predicted protein [Physcomitrella paten... 575 e-162
ref|YP_001685152.1| isocitrate dehydrogenase, NADP-dependen... 575 e-162
ref|NP_196963.2| isocitrate dehydrogenase, putative / NADP+... 575 e-162
ref|XP_001426548.1| hypothetical protein GSPATT00029781001 ... 575 e-162
sp|Q40345|IDHP_MEDSA Isocitrate dehydrogenase [NADP], chlor... 575 e-162
emb|CAM77136.1| Isocitrate/isopropylmalate dehydrogenase [M... 575 e-162
emb|CAD24779.1| isocitrate dehydrogenase [Cucumis sativus] 574 e-162
emb|CAA65504.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 574 e-162
ref|YP_002826161.1| NADP isocitrate dehydrogenase [Rhizobiu... 574 e-162
gb|AAD51361.1|AF176669_1 NADP-isocitrate dehydrogenase [Cit... 574 e-162
ref|NP_001053269.1| Os04g0508200 [Oryza sativa (japonica cu... 574 e-162
ref|YP_001623415.1| isocitrate dehydrogenase (NADP) [Reniba... 574 e-162
ref|YP_872148.1| isocitrate dehydrogenase [Acidothermus cel... 573 e-162
sp|P50218|IDHC_TOBAC Isocitrate dehydrogenase [NADP] (Oxalo... 573 e-162
ref|YP_706173.1| isocitrate dehydrogenase [Rhodococcus sp. ... 573 e-161
dbj|BAA34113.1| NADP specific isocitrate dehydrogenase [Dau... 573 e-161
ref|NP_421325.1| isocitrate dehydrogenase [Caulobacter cres... 573 e-161
ref|XP_001878769.1| predicted protein [Laccaria bicolor S23... 572 e-161
emb|CAE04728.1| OSJNBa0043L24.16 [Oryza sativa (japonica cu... 572 e-161
gb|AAR05796.1| NADP+-isocitrate dehydrogenase [Pinus pinaster] 571 e-161
ref|NP_354851.2| isocitrate dehydrogenase [Agrobacterium tu... 571 e-161
ref|ZP_03896321.1| isocitrate dehydrogenase (NADP) [Dyadoba... 571 e-161
gb|EAY99113.1| hypothetical protein OsI_020346 [Oryza sativ... 570 e-161
gb|ABA18651.1| cytosolic NADP+-isocitrate dehydrogenase [Po... 570 e-161
ref|YP_001524781.1| NADP-dependent isocitrate dehydrogenase... 570 e-161
gb|ABL97438.1| isocitrate dehydrogenase [uncultured marine ... 570 e-161
gb|AAT44354.1| isocitrate dehydrogenase [Crassostrea gigas] 569 e-160
ref|YP_002783489.1| isocitrate dehydrogenase [Rhodococcus o... 569 e-160
gb|AAS49171.1| NADP-dependent isocitrate dehydrogenase [Pis... 569 e-160
ref|XP_955850.1| hypothetical protein NCU03857 [Neurospora ... 568 e-160
gb|ABK25438.1| unknown [Picea sitchensis] 568 e-160
ref|ZP_01885694.1| isocitrate dehydrogenase [Pedobacter sp.... 568 e-160
gb|AAT06312.1| isocitrate dehydrogenase [Rhizobium legumino... 568 e-160
emb|CAH67563.1| OSIGBa0101P20.6 [Oryza sativa (indica culti... 568 e-160
ref|XP_001020930.2| dehydrogenase, isocitrate/isopropylmala... 567 e-160
ref|YP_002761841.1| NADP-dependent isocitrate dehydrogenase... 567 e-160
ref|YP_768215.1| isocitrate dehydrogenase [Rhizobium legumi... 567 e-160
ref|YP_673828.1| isocitrate dehydrogenase [Mesorhizobium sp... 567 e-160
ref|NP_101923.1| isocitrate dehydrogenase [Mesorhizobium lo... 567 e-160
dbj|BAE48792.1| NADP-isocitrate dehydrogenase [Codonopsis l... 567 e-160
emb|CAN72808.1| hypothetical protein [Vitis vinifera] >gi|1... 567 e-160
ref|YP_001370537.1| isocitrate dehydrogenase, NADP-dependen... 567 e-160
gb|EDT29808.1| isocitrate dehydrogenase, NADP-dependent [Ol... 566 e-159
ref|ZP_03819206.1| isocitrate dehydrogenase (NADP) [Actinos... 566 e-159
ref|ZP_02295934.1| isocitrate dehydrogenase, NADP-dependent... 565 e-159
ref|ZP_03869030.1| isocitrate dehydrogenase (NADP) [Jonesia... 565 e-159
pir||S33612 isocitrate dehydrogenase (NADP) (EC 1.1.1.42) -... 565 e-159
emb|CAB87626.1| isocitrate dehydrogenase-like protein [Arab... 565 e-159
gb|AAA33978.1| NADPH-specific isocitrate dehydrogenase 565 e-159
ref|XP_569234.1| isocitrate dehydrogenase (NADP+) [Cryptoco... 565 e-159
ref|YP_001413846.1| isocitrate dehydrogenase, NADP-dependen... 565 e-159
ref|YP_001204807.1| isocitrate dehydrogenase [Bradyrhizobiu... 565 e-159
ref|ZP_02858718.1| isocitrate dehydrogenase, NADP-dependent... 565 e-159
ref|XP_569233.1| isocitrate dehydrogenase (NADP+) [Cryptoco... 565 e-159
ref|NP_772387.1| isocitrate dehydrogenase [Bradyrhizobium j... 565 e-159
ref|ZP_02188085.1| Isocitrate dehydrogenase [alpha proteoba... 564 e-159
ref|XP_001226620.1| conserved hypothetical protein [Chaetom... 564 e-159
ref|YP_001849499.1| isocitrate dehydrogenase [NADP] Icd1 [M... 564 e-159
ref|YP_002765452.1| NADP-dependent isocitrate dehydrogenase... 564 e-159
ref|NP_176768.1| isocitrate dehydrogenase, putative / NADP+... 564 e-159
ref|NP_509875.1| C34F6.8 [Caenorhabditis elegans] >gi|38747... 564 e-159
ref|YP_290624.1| isocitrate dehydrogenase [Thermobifida fus... 564 e-159
ref|YP_117132.1| isocitrate dehydrogenase [Nocardia farcini... 563 e-159
ref|ZP_00056387.1| COG0538: Isocitrate dehydrogenases [Magn... 563 e-159
ref|YP_425448.1| isocitrate dehydrogenase [Rhodospirillum r... 563 e-159
ref|ZP_02124492.1| Isocitrate dehydrogenase (NADP(+)) [Meth... 563 e-159
ref|ZP_03813993.1| isocitrate dehydrogenase (NADP) [Beutenb... 563 e-159
ref|YP_001241304.1| isocitrate dehydrogenase [Bradyrhizobiu... 563 e-158
ref|ZP_02166681.1| isocitrate dehydrogenase [Hoeflea photot... 563 e-158
gb|AAM13090.1| similar to NADP-specific isocitrate dehydrog... 563 e-158
sp|Q06197|IDHC_SOYBN Isocitrate dehydrogenase [NADP] (Oxalo... 563 e-158
ref|ZP_03891012.1| isocitrate dehydrogenase (NADP) [Geoderm... 563 e-158
dbj|BAC77063.1| NADP-specific isocitrate dehydrogenase [Lup... 562 e-158
ref|XP_001903959.1| unnamed protein product [Podospora anse... 562 e-158
ref|YP_419971.1| isocitrate dehydrogenase [Magnetospirillum... 562 e-158
ref|YP_266067.1| isocitrate dehydrogenase [Candidatus Pelag... 562 e-158
ref|YP_001419447.1| isocitrate dehydrogenase, NADP-dependen... 561 e-158
ref|YP_001769504.1| isocitrate dehydrogenase, NADP-dependen... 561 e-158
emb|CAD24782.1| isocitrate dehydrogenase [Arabidopsis thali... 561 e-158
dbj|BAC77064.1| NADP-specific isocitrate dehydrogenase [Lup... 561 e-158
ref|ZP_00952302.1| isocitrate dehydrogenase [Oceanicaulis a... 561 e-158
ref|XP_451683.1| unnamed protein product [Kluyveromyces lac... 561 e-158
ref|XP_001676039.1| Hypothetical protein CBG17397 [Caenorha... 561 e-158
ref|XP_645284.1| isocitrate dehydrogenase (NADP+) [Dictyost... 560 e-158
emb|CAO64975.1| unnamed protein product [Vitis vinifera] 560 e-158
gb|AAM65674.1| isocitrate dehydrogenase, putative [Arabidop... 560 e-158
ref|ZP_03922528.1| isocitrate dehydrogenase [Mobiluncus cur... 559 e-157
ref|NP_217856.1| isocitrate dehydrogenase [Mycobacterium tu... 559 e-157
gb|EAY58582.1| isocitrate dehydrogenase [NADP] icd1 [Mycoba... 559 e-157
ref|NP_962389.1| isocitrate dehydrogenase [Mycobacterium av... 559 e-157
ref|XP_001593497.1| hypothetical protein SS1G_04924 [Sclero... 558 e-157
emb|CAA63220.1| isocitrate dehydrogenase (NAD+) [Solanum tu... 558 e-157
ref|YP_001108727.1| isocitrate dehydrogenase [Saccharopolys... 558 e-157
ref|YP_979491.1| isocitrate dehydrogenase [Mycobacterium bo... 558 e-157
ref|YP_883449.1| isocitrate dehydrogenase [Mycobacterium av... 557 e-157
ref|YP_001223282.1| isocitrate dehydrogenase [Clavibacter m... 556 e-156
ref|YP_001709366.1| isocitrate dehydrogenase [Clavibacter m... 556 e-156
ref|ZP_03993927.1| isocitrate dehydrogenase [Mobiluncus mul... 555 e-156
ref|YP_033790.1| isocitrate dehydrogenase [Bartonella hense... 555 e-156
ref|YP_001832264.1| isocitrate dehydrogenase, NADP-dependen... 555 e-156
gb|AAC50455.1| isocitrate dehydrogenase 555 e-156
ref|YP_001609735.1| NADP-dependent isocitrate dehydrogenase... 555 e-156
ref|YP_032403.1| isocitrate dehydrogenase [Bartonella quint... 555 e-156
ref|ZP_01046178.1| isocitrate dehydrogenase NADP-dependent ... 554 e-156
ref|ZP_01228834.1| NADP dependent isocitrate dehydrogenase ... 554 e-156
ref|YP_576902.1| isocitrate dehydrogenase [Nitrobacter hamb... 553 e-156
ref|YP_001758392.1| isocitrate dehydrogenase, NADP-dependen... 553 e-156
ref|YP_062774.1| isocitrate dehydrogenase [Leifsonia xyli s... 553 e-156
ref|ZP_02955422.1| isocitrate dehydrogenase, NADP-dependent... 553 e-155
ref|YP_756242.1| isocitrate dehydrogenase [Maricaulis maris... 552 e-155
gb|EAY73288.1| hypothetical protein OsI_001135 [Oryza sativ... 552 e-155
ref|XP_390523.1| hypothetical protein FG10347.1 [Gibberella... 551 e-155
ref|ZP_01130474.1| isocitrate dehydrogenase [marine actinob... 551 e-155
ref|XP_847200.1| isocitrate dehydrogenase [NADP], mitochond... 551 e-155
ref|YP_001833636.1| isocitrate dehydrogenase, NADP-dependen... 551 e-155
ref|NP_926944.1| isocitrate dehydrogenase [Gloeobacter viol... 551 e-155
ref|ZP_01440188.1| Isocitrate/isopropylmalate dehydrogenase... 551 e-155
sp|P79089|IDHP_ASPNG Isocitrate dehydrogenase [NADP], mitoc... 550 e-155
ref|XP_725505.1| isocitrate dehydrogenase, NADP-dependent [... 550 e-155
ref|YP_317907.1| isocitrate dehydrogenase [Nitrobacter wino... 550 e-155
ref|ZP_01546031.1| isocitrate dehydrogenase [Stappia aggreg... 550 e-155
ref|XP_754749.1| isocitrate dehydrogenase Idp1 [Aspergillus... 550 e-154
gb|EDP52872.1| isocitrate dehydrogenase Idp1, putative [Asp... 550 e-154
ref|XP_001614236.1| isocitrate dehydrogenase [NADP], mitoch... 549 e-154
ref|YP_989041.1| isocitrate dehydrogenase [Bartonella bacil... 549 e-154
ref|YP_682929.1| isocitrate dehydrogenase [Roseobacter deni... 549 e-154
ref|YP_001233708.1| isocitrate dehydrogenase [Acidiphilium ... 549 e-154
ref|NP_594105.1| isocitrate dehydrogenase Idp1 [Schizosacch... 548 e-154
ref|XP_001240510.1| isocitrate dehydrogenase NADP, mitochon... 548 e-154
ref|XP_001384028.1| Isocitrate dehydrogenase [NADP], mitoch... 548 e-154
ref|YP_487337.1| isocitrate dehydrogenase [Rhodopseudomonas... 548 e-154
ref|YP_001168561.1| isocitrate dehydrogenase [Rhodobacter s... 547 e-154
ref|YP_909639.1| isocitrate dehydrogenase [Bifidobacterium ... 546 e-154
ref|YP_568874.1| isocitrate dehydrogenase [Rhodopseudomonas... 546 e-154
ref|ZP_02302766.1| isocitrate dehydrogenase, NADP-dependent... 546 e-154
ref|XP_001400371.1| precursor of mitochondrial isocitrate d... 546 e-154
ref|YP_001169228.1| isocitrate dehydrogenase [Rhodobacter s... 546 e-153
ref|NP_949171.1| isocitrate dehydrogenase [Rhodopseudomonas... 546 e-153
ref|YP_531457.1| isocitrate dehydrogenase [Rhodopseudomonas... 546 e-153
ref|XP_813368.1| isocitrate dehydrogenase [NADP], mitochond... 546 e-153
gb|AAK76730.1| mitochondrial NADP-dependent isocitrate dehy... 545 e-153
ref|XP_001350171.1| isocitrate dehydrogenase (NADP), mitoch... 545 e-153
ref|YP_617009.1| isocitrate dehydrogenase [Sphingopyxis ala... 544 e-153
ref|YP_001363715.1| isocitrate dehydrogenase, NADP-dependen... 544 e-153
ref|XP_001017274.1| isocitrate dehydrogenase, NADP-dependen... 544 e-153
ref|ZP_02963068.1| isocitrate dehydrogenase [Bifidobacteriu... 543 e-153
gb|ABF20272.1| mitochondrial isocitrate dehydrogenase [Leis... 543 e-152
>ref|NP_005887.2| isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens]
sp|O75874|IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
pdb|1T09|A Chain A, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex Nadp
pdb|1T09|B Chain B, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex Nadp
pdb|1T0L|A Chain A, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|B Chain B, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|C Chain C, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|D Chain D, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
gb|AAD29284.1|AF113917_1 NADP+-dependent isocitrate dehydrogenase [Homo sapiens]
gb|AAH12846.1| IDH1 protein [Homo sapiens]
emb|CAG46496.1| IDH1 [Homo sapiens]
gb|AAX93221.1| unknown [Homo sapiens]
gb|EAW70439.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|EAW70441.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|EAW70442.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|ABM82361.1| isocitrate dehydrogenase 1 (NADP+), soluble [synthetic construct]
gb|ABW03396.1| isocitrate dehydrogenase 1 (NADP+), soluble [synthetic construct]
Length = 414
Score = 856 bits (2211), Expect = 0.0, Method: Composition-based stats.
Identities = 414/414 (100%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>gb|AAH93020.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens]
Length = 414
Score = 855 bits (2208), Expect = 0.0, Method: Composition-based stats.
Identities = 413/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAE+AHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAESAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAG38738.1| IDH1 [Homo sapiens]
Length = 414
Score = 855 bits (2208), Expect = 0.0, Method: Composition-based stats.
Identities = 413/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVE+TYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAB66637.1| hypothetical protein [Homo sapiens]
emb|CAL37490.1| hypothetical protein [synthetic construct]
Length = 414
Score = 852 bits (2201), Expect = 0.0, Method: Composition-based stats.
Identities = 412/414 (99%), Positives = 413/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWV+PIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>ref|XP_001141655.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 1
[Pan troglodytes]
ref|XP_001141734.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 2
[Pan troglodytes]
ref|XP_001141810.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 3
[Pan troglodytes]
ref|XP_001141879.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 4
[Pan troglodytes]
ref|XP_001141947.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 5
[Pan troglodytes]
ref|XP_001142041.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 6
[Pan troglodytes]
ref|XP_001142113.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 7
[Pan troglodytes]
ref|XP_001142197.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 8
[Pan troglodytes]
Length = 414
Score = 852 bits (2201), Expect = 0.0, Method: Composition-based stats.
Identities = 412/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKRYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>sp|Q5R9C5|IDHC_PONPY Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
Length = 414
Score = 851 bits (2199), Expect = 0.0, Method: Composition-based stats.
Identities = 411/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVS+ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAD97653.1| hypothetical protein [Homo sapiens]
emb|CAL38069.1| hypothetical protein [synthetic construct]
emb|CAL37462.1| hypothetical protein [synthetic construct]
Length = 414
Score = 850 bits (2195), Expect = 0.0, Method: Composition-based stats.
Identities = 412/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHN E GGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>gb|AAD02918.1| NADP-dependent isocitrate dehydrogenase [Homo sapiens]
Length = 414
Score = 849 bits (2194), Expect = 0.0, Method: Composition-based stats.
Identities = 411/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILK YDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKIYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTN IASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNLIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACI+GLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIRGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAG38553.1| IDH1 [Homo sapiens]
Length = 414
Score = 849 bits (2193), Expect = 0.0, Method: Composition-based stats.
Identities = 411/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWV+PIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTK LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKGLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>ref|XP_001107627.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 1
[Macaca mulatta]
ref|XP_001107810.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 2
[Macaca mulatta]
ref|XP_001107875.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 3
[Macaca mulatta]
ref|XP_001107934.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 4
[Macaca mulatta]
ref|XP_001107992.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 5
[Macaca mulatta]
Length = 414
Score = 848 bits (2191), Expect = 0.0, Method: Composition-based stats.
Identities = 410/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVE+QGDEMTRIIWELIKEKLIFPYVELDL SYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVELQGDEMTRIIWELIKEKLIFPYVELDLQSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAH91635.1| hypothetical protein [Pongo abelii]
Length = 414
Score = 848 bits (2190), Expect = 0.0, Method: Composition-based stats.
Identities = 409/414 (98%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKD FQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDTFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPI SIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIVSIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVS+ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAH89719.1| hypothetical protein [Pongo abelii]
Length = 414
Score = 846 bits (2185), Expect = 0.0, Method: Composition-based stats.
Identities = 409/414 (98%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWE IKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWEQIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVS+ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA AKL
Sbjct: 361 EVSVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLALAKL 414
>ref|XP_850187.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 2 [Canis familiaris]
ref|XP_536047.2| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 1 [Canis familiaris]
Length = 414
Score = 836 bits (2160), Expect = 0.0, Method: Composition-based stats.
Identities = 401/414 (96%), Positives = 408/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDG++K+TYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL IKLAQAKL
Sbjct: 361 EVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL 414
>ref|XP_001505172.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Cytosolic NADP-isocitrate dehydrogenase)
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) [Equus caballus]
Length = 414
Score = 835 bits (2157), Expect = 0.0, Method: Composition-based stats.
Identities = 400/414 (96%), Positives = 408/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFP+VELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPHVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPG+VEITYTPSDG+QK TYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGRVEITYTPSDGSQKRTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQY+SQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYRSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELGFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 DVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>ref|NP_113698.1| isocitrate dehydrogenase 1 (NADP+), soluble [Rattus norvegicus]
sp|P41562|IDHC_RAT Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAA59356.1| cytosolic NADP-dependent isocitrate dehydrogenase
gb|EDL98861.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98863.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98864.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98865.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
Length = 414
Score = 833 bits (2151), Expect = 0.0, Method: Composition-based stats.
Identities = 399/414 (96%), Positives = 408/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DG+QKVTYLVH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKS+FE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSKFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02925.1| cytosolic NADP-dependent isocitrate dehydrogenase [Microtus
ochrogaster]
Length = 414
Score = 830 bits (2145), Expect = 0.0, Method: Composition-based stats.
Identities = 398/414 (96%), Positives = 407/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DG+QKVTYLVH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHSFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAW+RGLAHRA+LDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02924.1| cytosolic NADP-dependent isocitrate dehydrogenase [Microtus
mexicanus]
Length = 414
Score = 830 bits (2143), Expect = 0.0, Method: Composition-based stats.
Identities = 397/414 (95%), Positives = 407/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEIT+TP DG+QKVTYLVH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITFTPKDGSQKVTYLVHSFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAW+RGLAHRA+LDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>ref|NP_851355.2| isocitrate dehydrogenase 1 (NADP+), soluble [Bos taurus]
gb|AAI03369.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Bos taurus]
Length = 414
Score = 827 bits (2135), Expect = 0.0, Method: Composition-based stats.
Identities = 396/414 (95%), Positives = 404/414 (97%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEI+YTPSDG+ K YLVHNF E GGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKS+FE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL++KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAKL 414
>gb|AAH88986.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Mus musculus]
Length = 414
Score = 825 bits (2131), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 406/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEA+KK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEALKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>ref|NP_034627.3| isocitrate dehydrogenase 1 (NADP+), soluble [Mus musculus]
ref|NP_001104790.1| isocitrate dehydrogenase 1 (NADP+), soluble [Mus musculus]
dbj|BAE36075.1| unnamed protein product [Mus musculus]
dbj|BAE30207.1| unnamed protein product [Mus musculus]
dbj|BAE39299.1| unnamed protein product [Mus musculus]
dbj|BAE34873.1| unnamed protein product [Mus musculus]
dbj|BAE28720.1| unnamed protein product [Mus musculus]
gb|EDL00223.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Mus
musculus]
gb|EDL00225.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Mus
musculus]
Length = 414
Score = 825 bits (2131), Expect = 0.0, Method: Composition-based stats.
Identities = 396/414 (95%), Positives = 406/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>dbj|BAE39644.1| unnamed protein product [Mus musculus]
Length = 414
Score = 825 bits (2130), Expect = 0.0, Method: Composition-based stats.
Identities = 396/414 (95%), Positives = 406/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIKGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD34457.1|AF136009_1 cytosolic NADP+-dependent isocitrate dehydrogenase [Bos taurus]
Length = 414
Score = 824 bits (2129), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 403/414 (97%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEI+YTPSDG+ K YLVHNF E GGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKS+FE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQET TNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETLTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL++KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAKL 414
>sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02919.1| NADP-dependent isocitrate dehydrogenase [Mus musculus]
Length = 414
Score = 824 bits (2129), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 405/414 (97%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ I YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQNICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>ref|NP_001009276.1| cytosolic NADP-isocitrate dehydrogenase [Ovis aries]
sp|Q6XUZ5|IDHC_SHEEP Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAP41947.1| cytosolic NADP-isocitrate dehydrogenase [Ovis aries]
Length = 414
Score = 823 bits (2127), Expect = 0.0, Method: Composition-based stats.
Identities = 394/414 (95%), Positives = 401/414 (96%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS KI GGSVVEMQGDEMTRIIWELIKEKLIFPYV+LDLHSYDL IENRDATNDQVTKDA
Sbjct: 1 MSHKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVDLDLHSYDLSIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEI YTPSDG+ K YLVHNF E GGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEICYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GM+NQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMFNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL++KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAKL 414
>dbj|BAC39792.1| unnamed protein product [Mus musculus]
Length = 422
Score = 823 bits (2127), Expect = 0.0, Method: Composition-based stats.
Identities = 394/413 (95%), Positives = 405/413 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQA+
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAQ 413
>ref|XP_860821.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 4 [Canis familiaris]
Length = 415
Score = 819 bits (2116), Expect = 0.0, Method: Composition-based stats.
Identities = 395/415 (95%), Positives = 404/415 (97%), Gaps = 1/415 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFE-EGGGVA 179
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDG++K+TYL+ +GGGVA
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYLIQVLSFKGGGVA 180
Query: 180 MGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQF 239
MGMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQF
Sbjct: 181 MGMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQF 240
Query: 240 EAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPD 299
EAQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPD
Sbjct: 241 EAQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPD 300
Query: 300 GKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANAL 359
GKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA AL
Sbjct: 301 GKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKAL 360
Query: 360 EEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EEV +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL IKLAQAKL
Sbjct: 361 EEVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL 415
>pdb|2CMJ|A Chain A, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase
pdb|2CMJ|B Chain B, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase
pdb|2CMV|A Chain A, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase Complexed With Cadmium And Citrate
pdb|2CMV|B Chain B, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase Complexed With Cadmium And Citrate
Length = 410
Score = 817 bits (2110), Expect = 0.0, Method: Composition-based stats.
Identities = 392/410 (95%), Positives = 401/410 (97%)
Query: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDAAEA
Sbjct: 1 KIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEA 60
Query: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
IKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 61 IKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 120
Query: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAMGMY
Sbjct: 121 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAMGMY 180
Query: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQK 243
NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFEAQ
Sbjct: 181 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQN 240
Query: 244 IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTV 303
I YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDGKTV
Sbjct: 241 ICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTV 300
Query: 304 EAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVS 363
EAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE+V
Sbjct: 301 EAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVC 360
Query: 364 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAK
Sbjct: 361 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAK 410
>ref|XP_860853.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 5 [Canis familiaris]
Length = 408
Score = 816 bits (2108), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 402/414 (97%), Gaps = 6/414 (1%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDG++K+TYL GGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYL------GGGVAM 174
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 175 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 234
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 235 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 294
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 295 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 354
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL IKLAQAKL
Sbjct: 355 EVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL 408
>ref|XP_001511049.1| PREDICTED: similar to cytosolic NADP-dependent isocitrate
dehydrogenase [Ornithorhynchus anatinus]
Length = 415
Score = 789 bits (2037), Expect = 0.0, Method: Composition-based stats.
Identities = 374/415 (90%), Positives = 396/415 (95%), Gaps = 1/415 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS KI GGSVVEMQGDEMTR+IWELIKEKLIFPYV+LDLHSYDLGIENRDATND+VT +A
Sbjct: 1 MSSKICGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIENRDATNDKVTSEA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVP PGKVE+ YTP DG + VTYLVHNFE GGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPRPGKVEMVYTPQDGGKAVTYLVHNFEAGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI DFAHSSFQMALSK WPLY+STKNTILK+YDGRFKDIFQEIY+KQY+S+FE
Sbjct: 181 GMYNLDQSIRDFAHSSFQMALSKSWPLYMSTKNTILKRYDGRFKDIFQEIYEKQYRSKFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRH+RM+QKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+ FA LE
Sbjct: 301 KTVEAEAAHGTVTRHFRMHQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSTFATTLE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA-QAKL 414
+V +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLA QAKL
Sbjct: 361 DVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLASQAKL 415
>ref|XP_001365492.1| PREDICTED: similar to cytosolic NADP-dependent isocitrate
dehydrogenase [Monodelphis domestica]
Length = 414
Score = 787 bits (2033), Expect = 0.0, Method: Composition-based stats.
Identities = 369/414 (89%), Positives = 397/414 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI+GGSVVEMQGDEMTR+IW+LIK+KLIFPYV LDLHSYDLGIE+RD T+DQVT DA
Sbjct: 1 MSQKINGGSVVEMQGDEMTRVIWDLIKQKLIFPYVNLDLHSYDLGIEHRDETDDQVTIDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPI+IGRHAYGDQYRATDFVVPGPGKVEI+YTP DG++ VTYL+HNFE+ GGVAM
Sbjct: 121 VNGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEISYTPRDGSKTVTYLIHNFEDCGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI DFAHSSFQMAL+KGWPLY+STKNTILKKYDGRFKDIFQ+IYD YKS+FE
Sbjct: 181 GMYNLDQSIMDFAHSSFQMALTKGWPLYMSTKNTILKKYDGRFKDIFQKIYDTHYKSKFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQA+KSEGGF+WACKNYDGDVQSDS+AQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSIAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLD+NKEL FA LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDDNKELGTFATILE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIE+GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKL ENLK KLAQAKL
Sbjct: 361 EVCIETIESGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLAENLKAKLAQAKL 414
>gb|ABU41004.1| isocitrate dehydrogenase 1 [Anser anser]
Length = 415
Score = 785 bits (2026), Expect = 0.0, Method: Composition-based stats.
Identities = 369/410 (90%), Positives = 393/410 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTR+IWELIKEKLIFPYV+LDLHSYDLGIE+RDATND+VT +A
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIEHRDATNDKVTVEA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK++VG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYHVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPI+IGRHAYGDQYRATDFVVPGPGKVE+TYTP DG + VTYLVHNFE GGVAM
Sbjct: 121 VSGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEMTYTPGDGGKPVTYLVHNFESCGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GM+N D+SI+DFAHSSFQMALSKGWPLY+STKNTILK+YDGRFKDIFQEIYD++YKSQFE
Sbjct: 181 GMFNLDQSIKDFAHSSFQMALSKGWPLYMSTKNTILKRYDGRFKDIFQEIYDREYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQA+KSEGGF+WACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAWTRGLAHRAKLDNN L FA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWTRGLAHRAKLDNNTSLKTFAAALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA 410
EV IETIE+GFMTKDLAACIKGLPNV RSDYLNTFEFMDKL ENLK KLA
Sbjct: 361 EVCIETIESGFMTKDLAACIKGLPNVTRSDYLNTFEFMDKLAENLKGKLA 410
>ref|XP_421965.2| PREDICTED: similar to cytosolic NADP-dependent isocitrate
dehydrogenase [Gallus gallus]
Length = 415
Score = 784 bits (2025), Expect = 0.0, Method: Composition-based stats.
Identities = 369/410 (90%), Positives = 392/410 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTR+IWELIKEKLIFPYV+LDLHSYDLGIE+RDATND+VT +A
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIEHRDATNDKVTVEA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK++VG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYHVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPI+IGRHAYGDQYRATDFVVPGPGKVE+TYTP DG + VTYLVHNFE GGVAM
Sbjct: 121 VSGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEMTYTPGDGGKPVTYLVHNFESCGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI+DFAHSSFQMALSKGWPLY+STKNTILK+YDGRFKDIFQEIYD++YKSQFE
Sbjct: 181 GMYNLDQSIKDFAHSSFQMALSKGWPLYMSTKNTILKRYDGRFKDIFQEIYDREYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQA+KSEGGF+WACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAWTRGLAHRAKLDNN L FA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWTRGLAHRAKLDNNTSLKTFATALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA 410
EV IETIE+GFMTKDLAACIKGLPNV RSDYLNTFEFMDKL NLK KLA
Sbjct: 361 EVCIETIESGFMTKDLAACIKGLPNVTRSDYLNTFEFMDKLAANLKGKLA 410
>ref|NP_001088022.1| hypothetical protein LOC494713 [Xenopus laevis]
gb|AAH82651.1| LOC494713 protein [Xenopus laevis]
Length = 415
Score = 776 bits (2005), Expect = 0.0, Method: Composition-based stats.
Identities = 363/410 (88%), Positives = 391/410 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI+GGSVVEMQGDEMTR+IW+LIKEKLI PYVELDLHSYDLG+ENRDAT+DQVT DA
Sbjct: 1 MSKKINGGSVVEMQGDEMTRVIWDLIKEKLILPYVELDLHSYDLGMENRDATDDQVTVDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVG+KCATITPDEKRVEEF LKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEKRVEEFNLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGW+KPIIIGRHAYGDQYRATDFVVPGPGKVEI++TP DG + + Y++HNFE+ GGVA+
Sbjct: 121 VSGWIKPIIIGRHAYGDQYRATDFVVPGPGKVEISFTPKDGGEAIKYVIHNFEDCGGVAL 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI DFAHSSFQMALSK WPLY+STKNTILK+YDGRFKDIFQEIY+K+YKSQFE
Sbjct: 181 GMYNTDQSIRDFAHSSFQMALSKSWPLYMSTKNTILKRYDGRFKDIFQEIYEKEYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 ENKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAW+RGL HRAKLDNN+EL FA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLDHRAKLDNNQELKNFATALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA 410
EV IETIEAGFMTKDLAACIKGLPNVQR DYL+TFEFMDKLGENL++KLA
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRGDYLSTFEFMDKLGENLQLKLA 410
>gb|ABD77215.1| isocitrate dehydrogenase 1 [Homo sapiens]
Length = 371
Score = 776 bits (2005), Expect = 0.0, Method: Composition-based stats.
Identities = 371/371 (100%), Positives = 371/371 (100%)
Query: 30 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 89
LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 90 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 149
QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 150 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 209
GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 180
Query: 210 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC 269
STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC
Sbjct: 181 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC 240
Query: 270 KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP 329
KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP
Sbjct: 241 KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP 300
Query: 330 IASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRS 389
IASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRS
Sbjct: 301 IASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRS 360
Query: 390 DYLNTFEFMDK 400
DYLNTFEFMDK
Sbjct: 361 DYLNTFEFMDK 371
>gb|ABD77209.1| isocitrate dehydrogenase 1 [Rattus norvegicus]
Length = 378
Score = 771 bits (1991), Expect = 0.0, Method: Composition-based stats.
Identities = 366/378 (96%), Positives = 374/378 (98%)
Query: 28 EKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFK 87
EKLI PYVELDLHSYDLGIENRDATNDQVTKDAAEAIKK+NVGVKCATITPDEKRVEEFK
Sbjct: 1 EKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFK 60
Query: 88 LKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVP 147
LKQMWKSPNGTIRNILGGTVFREAIICKNIPRLV+GWVKPIIIGRHAYGDQYRATDFVVP
Sbjct: 61 LKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVP 120
Query: 148 GPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPL 207
GPGKVEITYTP DG+QKVTYLVH+FEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPL
Sbjct: 121 GPGKVEITYTPKDGSQKVTYLVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPL 180
Query: 208 YLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIW 267
YLSTKNTILKKYDGRFKDIFQEIYDKQYKS+FEAQKIWYEHRLIDDMVAQAMKSEGGFIW
Sbjct: 181 YLSTKNTILKKYDGRFKDIFQEIYDKQYKSKFEAQKIWYEHRLIDDMVAQAMKSEGGFIW 240
Query: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETST 327
ACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDGKTVEAEAAHGTVTRHYRMYQKGQETST
Sbjct: 241 ACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETST 300
Query: 328 NPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQ 387
NPIASIFAW+RGLAHRAKLDNN EL+FFANALEEV IETIEAGFMTKDLAACIKGLPNVQ
Sbjct: 301 NPIASIFAWSRGLAHRAKLDNNTELSFFANALEEVCIETIEAGFMTKDLAACIKGLPNVQ 360
Query: 388 RSDYLNTFEFMDKLGENL 405
RSDYLNTFEFMDKLGENL
Sbjct: 361 RSDYLNTFEFMDKLGENL 378
>gb|ABD77216.1| isocitrate dehydrogenase 1 [Aotus trivirgatus]
Length = 371
Score = 768 bits (1982), Expect = 0.0, Method: Composition-based stats.
Identities = 364/371 (98%), Positives = 369/371 (99%)
Query: 28 EKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFK 87
E LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKK+NVGVKCATITPDEKRVEEFK
Sbjct: 1 ESLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFK 60
Query: 88 LKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVP 147
LKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW+KPIIIGRHAYGDQYRATDFVVP
Sbjct: 61 LKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWIKPIIIGRHAYGDQYRATDFVVP 120
Query: 148 GPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPL 207
GPGKVEITYTP+DGTQKVTYL+HNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPL
Sbjct: 121 GPGKVEITYTPTDGTQKVTYLIHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPL 180
Query: 208 YLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIW 267
YLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIW
Sbjct: 181 YLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIW 240
Query: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETST 327
ACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETST
Sbjct: 241 ACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETST 300
Query: 328 NPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQ 387
NPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV IETIEAGFMTKDLAACIKGLPNVQ
Sbjct: 301 NPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVCIETIEAGFMTKDLAACIKGLPNVQ 360
Query: 388 RSDYLNTFEFM 398
RSDYLNTFEF+
Sbjct: 361 RSDYLNTFEFI 371
>gb|ABD77211.1| isocitrate dehydrogenase 1 [Cavia porcellus]
Length = 376
Score = 764 bits (1973), Expect = 0.0, Method: Composition-based stats.
Identities = 364/376 (96%), Positives = 369/376 (98%)
Query: 30 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 89
LIFPYVELDLHSYDLGIENRDAT+DQVTKDAAEAIKK+NVG+KCATITPDEKRVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATHDQVTKDAAEAIKKYNVGIKCATITPDEKRVEEFKLK 60
Query: 90 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 149
QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW+KPIIIGRHAYGDQYRATDFVVPGP
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWLKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 150 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 209
GKVEITYTPSDG+QKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL
Sbjct: 121 GKVEITYTPSDGSQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 180
Query: 210 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC 269
STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC
Sbjct: 181 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC 240
Query: 270 KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP 329
KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP
Sbjct: 241 KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP 300
Query: 330 IASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRS 389
IASIFAWTRGLAHRAKLDNNKEL FFA ALEEV IETIEAGFMTKDLAACIKGLPNVQRS
Sbjct: 301 IASIFAWTRGLAHRAKLDNNKELDFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQRS 360
Query: 390 DYLNTFEFMDKLGENL 405
DYLNTFE KLG NL
Sbjct: 361 DYLNTFELHGKLGXNL 376
>gb|ABD77208.1| isocitrate dehydrogenase 1 [Mus musculus]
Length = 378
Score = 763 bits (1969), Expect = 0.0, Method: Composition-based stats.
Identities = 362/378 (95%), Positives = 371/378 (98%)
Query: 28 EKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFK 87
EKLI PYVELDLHSYDLGIENRDATNDQVTKDAAEAIKK+NVGVKCATITPDEKRVEEFK
Sbjct: 1 EKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFK 60
Query: 88 LKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVP 147
LKQMWKSPNGTIRNILGGTVFREAIICKNIPRLV+GWVKPIIIGRHAYGDQYRATDFVVP
Sbjct: 61 LKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVP 120
Query: 148 GPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPL 207
GPGKVEITYTP DGTQKVTY+VH+FEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPL
Sbjct: 121 GPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPL 180
Query: 208 YLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIW 267
YLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFEAQ I YEHRLIDDMVAQAMKSEGGFIW
Sbjct: 181 YLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQNICYEHRLIDDMVAQAMKSEGGFIW 240
Query: 268 ACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETST 327
ACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDGKTVEAEAAHGTVTRHYRMYQKGQETST
Sbjct: 241 ACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETST 300
Query: 328 NPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQ 387
NPIASIFAW+RGLAHRAKLDNN EL+FFA ALE+V IETIEAGFMTKDLAACIKGLPNVQ
Sbjct: 301 NPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVCIETIEAGFMTKDLAACIKGLPNVQ 360
Query: 388 RSDYLNTFEFMDKLGENL 405
RSDYLNTFEFMDKLGENL
Sbjct: 361 RSDYLNTFEFMDKLGENL 378
>gb|ABD77213.1| isocitrate dehydrogenase 1 [Oryctolagus cuniculus]
Length = 376
Score = 760 bits (1963), Expect = 0.0, Method: Composition-based stats.
Identities = 361/374 (96%), Positives = 368/374 (98%)
Query: 30 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 89
+I+PYVELDLHSYDLGIENRDATNDQVTKDAAEAIKK+ VGVKCATITPDEKRVEEFKLK
Sbjct: 2 IIYPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYRVGVKCATITPDEKRVEEFKLK 61
Query: 90 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 149
QMWKSPNGTIRNILGGTVFREAIICKNIPRLV+GWVKPIIIGRHAYGDQYRATDFVVPGP
Sbjct: 62 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGP 121
Query: 150 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 209
GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL
Sbjct: 122 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 181
Query: 210 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC 269
STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC
Sbjct: 182 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC 241
Query: 270 KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP 329
KNYDGDVQSDSVAQGYGSLGMMTSVL+CPDGKTVEAEAAHGTVTRHYRM+QKGQETSTNP
Sbjct: 242 KNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMHQKGQETSTNP 301
Query: 330 IASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRS 389
IASIFAWTRGLAHRAKLDNNKEL+FFANALEEV IETIEAGFMTKDLAACIKGLPNVQRS
Sbjct: 302 IASIFAWTRGLAHRAKLDNNKELSFFANALEEVCIETIEAGFMTKDLAACIKGLPNVQRS 361
Query: 390 DYLNTFEFMDKLGE 403
DYLNTF FM L E
Sbjct: 362 DYLNTFXFMXXLKE 375
>gb|ABD77217.1| isocitrate dehydrogenase 1 [Tupaia glis]
Length = 369
Score = 752 bits (1941), Expect = 0.0, Method: Composition-based stats.
Identities = 357/368 (97%), Positives = 363/368 (98%)
Query: 31 IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQ 90
IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKK+NVGVKCATITPDEKRVEEFKLKQ
Sbjct: 2 IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQ 61
Query: 91 MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG 150
MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG
Sbjct: 62 MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG 121
Query: 151 KVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLS 210
KVEITYTPSDGTQKVTY+VHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMAL+KGWPLYLS
Sbjct: 122 KVEITYTPSDGTQKVTYVVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALAKGWPLYLS 181
Query: 211 TKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACK 270
TKNTILKKYDGRFKDIFQ+IY+KQYK QFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACK
Sbjct: 182 TKNTILKKYDGRFKDIFQDIYEKQYKPQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACK 241
Query: 271 NYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI 330
NYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI
Sbjct: 242 NYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI 301
Query: 331 ASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSD 390
ASIFAWTRGLAHRAKLDNNKEL FFA ALE+V IETIEAGFMTKDLAACIKGLPNVQRSD
Sbjct: 302 ASIFAWTRGLAHRAKLDNNKELDFFAKALEDVCIETIEAGFMTKDLAACIKGLPNVQRSD 361
Query: 391 YLNTFEFM 398
YLNTF FM
Sbjct: 362 YLNTFVFM 369
>gb|ABD77222.1| isocitrate dehydrogenase 1 [Diceros bicornis]
Length = 372
Score = 749 bits (1934), Expect = 0.0, Method: Composition-based stats.
Identities = 354/370 (95%), Positives = 363/370 (98%)
Query: 30 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 89
LIFPYV+LDLHSYDLGIENRDATNDQVTKDAAEAIKK+NVGVKCATITPDEKRVEEFKLK
Sbjct: 3 LIFPYVDLDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLK 62
Query: 90 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 149
QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP
Sbjct: 63 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 122
Query: 150 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 209
GKVEITYT SDG+QK TYLVHNFEEGGGVA+GMYNQDKSIEDFAHSSFQMALSK WPLYL
Sbjct: 123 GKVEITYTSSDGSQKRTYLVHNFEEGGGVALGMYNQDKSIEDFAHSSFQMALSKSWPLYL 182
Query: 210 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC 269
STKNTILKKYDGRFKDIFQEIYDKQY+SQFEAQKIWYEHRLIDDMVAQA+KSEGGFIWAC
Sbjct: 183 STKNTILKKYDGRFKDIFQEIYDKQYRSQFEAQKIWYEHRLIDDMVAQALKSEGGFIWAC 242
Query: 270 KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP 329
KNYDGDVQSDSVAQGYGSLGMMTSVL+CPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP
Sbjct: 243 KNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP 302
Query: 330 IASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRS 389
IASIFAWTRGLAHRAKLDNNKEL FFA ALEEV +ETIEAGFMTKDLAACIKGLPNVQRS
Sbjct: 303 IASIFAWTRGLAHRAKLDNNKELGFFAKALEEVCVETIEAGFMTKDLAACIKGLPNVQRS 362
Query: 390 DYLNTFEFMD 399
DYLNTF+ MD
Sbjct: 363 DYLNTFDIMD 372
>gb|ABD77221.1| isocitrate dehydrogenase 1 [Ceratotherium simum]
Length = 370
Score = 745 bits (1924), Expect = 0.0, Method: Composition-based stats.
Identities = 353/370 (95%), Positives = 362/370 (97%)
Query: 31 IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQ 90
IFPYV+LDLHSYDLGIENRDATNDQVTKDAAEAIKK+NVGVKCATITPDEKRVEEFKLKQ
Sbjct: 1 IFPYVDLDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQ 60
Query: 91 MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG 150
MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG
Sbjct: 61 MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG 120
Query: 151 KVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLS 210
KVEITYT SDG+QK TYLVH FEEGGGVA+GMYNQDKSIEDFAHSSFQMALSK WPLYLS
Sbjct: 121 KVEITYTSSDGSQKRTYLVHKFEEGGGVALGMYNQDKSIEDFAHSSFQMALSKSWPLYLS 180
Query: 211 TKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACK 270
TKNTILKKYDGRFKDIFQEIYDKQY+SQFEAQKIWYEHRLIDDMVAQA+KSEGGFIWACK
Sbjct: 181 TKNTILKKYDGRFKDIFQEIYDKQYRSQFEAQKIWYEHRLIDDMVAQALKSEGGFIWACK 240
Query: 271 NYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI 330
NYDGDVQSDSVAQGYGSLGMMTSVL+CPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI
Sbjct: 241 NYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI 300
Query: 331 ASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSD 390
ASIFAWTRGLAHRAKLDNNKEL FFA ALEEV +ETIEAGFMTKDLAACIKGLPNVQRSD
Sbjct: 301 ASIFAWTRGLAHRAKLDNNKELGFFAKALEEVCVETIEAGFMTKDLAACIKGLPNVQRSD 360
Query: 391 YLNTFEFMDK 400
YLNTF+ MDK
Sbjct: 361 YLNTFDIMDK 370
>gb|ABD77205.1| isocitrate dehydrogenase 1 [Loxodonta africana]
Length = 369
Score = 744 bits (1920), Expect = 0.0, Method: Composition-based stats.
Identities = 350/367 (95%), Positives = 360/367 (98%)
Query: 33 PYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMW 92
P+VELDLHSYDLGIENRDATNDQVTKDAAEA+KK+NVGVKCATITPDEKRVEEFKLKQMW
Sbjct: 3 PHVELDLHSYDLGIENRDATNDQVTKDAAEAVKKYNVGVKCATITPDEKRVEEFKLKQMW 62
Query: 93 KSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKV 152
KSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKV
Sbjct: 63 KSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKV 122
Query: 153 EITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTK 212
EITYTPSDG QKVTYLVH+FE+ GGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTK
Sbjct: 123 EITYTPSDGAQKVTYLVHDFEDCGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTK 182
Query: 213 NTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNY 272
NTILKKYDGRFKDIFQEIYDKQYKSQFEAQ IWYEHRLIDDMVAQAMKSEGGFIWACKNY
Sbjct: 183 NTILKKYDGRFKDIFQEIYDKQYKSQFEAQNIWYEHRLIDDMVAQAMKSEGGFIWACKNY 242
Query: 273 DGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIAS 332
DGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMY++G+ETSTNPIAS
Sbjct: 243 DGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYEQGRETSTNPIAS 302
Query: 333 IFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYL 392
IFAWTRGLAHRAKLDNN EL+FFA ALEEV IETIEAGF+TKDLAACIKGLPNVQRSDYL
Sbjct: 303 IFAWTRGLAHRAKLDNNNELSFFAKALEEVCIETIEAGFLTKDLAACIKGLPNVQRSDYL 362
Query: 393 NTFEFMD 399
NTF FMD
Sbjct: 363 NTFVFMD 369
>gb|ABD77218.1| isocitrate dehydrogenase 1 [Felis catus]
Length = 366
Score = 743 bits (1919), Expect = 0.0, Method: Composition-based stats.
Identities = 354/366 (96%), Positives = 360/366 (98%)
Query: 30 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 89
+IFPYVELDLHSYDLGIENRDAT DQVTKDAAEAIKK+NVGVKCATITPDEKRVEEFKLK
Sbjct: 1 IIFPYVELDLHSYDLGIENRDATGDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLK 60
Query: 90 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 149
QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 150 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 209
GKVEITYT SDG++K+TYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSK WPLYL
Sbjct: 121 GKVEITYTSSDGSKKMTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKSWPLYL 180
Query: 210 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC 269
STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ IWYEHRLIDDMVAQAMKSEGGFIWAC
Sbjct: 181 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQNIWYEHRLIDDMVAQAMKSEGGFIWAC 240
Query: 270 KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP 329
KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP
Sbjct: 241 KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP 300
Query: 330 IASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRS 389
IASIFAWTRGLAHRAKLDNNKEL+FFA ALEEV IETIEAGFMTKDLAACIKGLPNVQRS
Sbjct: 301 IASIFAWTRGLAHRAKLDNNKELSFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQRS 360
Query: 390 DYLNTF 395
DYLNTF
Sbjct: 361 DYLNTF 366
>gb|ABD77210.1| isocitrate dehydrogenase 1 [Mesocricetus auratus]
Length = 365
Score = 743 bits (1918), Expect = 0.0, Method: Composition-based stats.
Identities = 353/365 (96%), Positives = 358/365 (98%)
Query: 30 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 89
+I PYVELDLHSYDLGIENRDATNDQVTKDAAEAIKK+NVGVKCATITPDEKRVEEFKLK
Sbjct: 1 IILPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLK 60
Query: 90 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 149
QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 150 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 209
GKVEITYTP DGTQKVTY+VHNFEE GGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL
Sbjct: 121 GKVEITYTPKDGTQKVTYVVHNFEECGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 180
Query: 210 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC 269
STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC
Sbjct: 181 STKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWAC 240
Query: 270 KNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP 329
KNYDGDVQSDSVAQGYGSLGMMTSVL+CPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP
Sbjct: 241 KNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNP 300
Query: 330 IASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRS 389
IASIFAWTRGLAHRAKLDNN EL+ FA ALEEV IETIEAGFMTKDLAACIKGLPNVQRS
Sbjct: 301 IASIFAWTRGLAHRAKLDNNTELSIFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQRS 360
Query: 390 DYLNT 394
DYLNT
Sbjct: 361 DYLNT 365
>gb|ABD77214.1| isocitrate dehydrogenase 1 [Tadarida brasiliensis]
Length = 366
Score = 742 bits (1916), Expect = 0.0, Method: Composition-based stats.
Identities = 352/365 (96%), Positives = 359/365 (98%)
Query: 31 IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQ 90
IFPYVELDLHSYDLGIENRDATNDQVTKDAAEA+KK+NVGVKCATITPDEKRVEEFKLKQ
Sbjct: 1 IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAMKKYNVGVKCATITPDEKRVEEFKLKQ 60
Query: 91 MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG 150
MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GWVKPIIIGRHAYGDQYRATDFVVPGPG
Sbjct: 61 MWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWVKPIIIGRHAYGDQYRATDFVVPGPG 120
Query: 151 KVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLS 210
KVEITYTPSDG+ K TYLVHNFEEGGGVAMGMYNQD+SI+DFAHSSFQMALSK WPLYLS
Sbjct: 121 KVEITYTPSDGSPKKTYLVHNFEEGGGVAMGMYNQDESIKDFAHSSFQMALSKSWPLYLS 180
Query: 211 TKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACK 270
TKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACK
Sbjct: 181 TKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACK 240
Query: 271 NYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI 330
NYDGDVQSDSVAQGYGSLGMMTSVL+CPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI
Sbjct: 241 NYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI 300
Query: 331 ASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSD 390
ASIFAWTRGLAHRAKLDNNKEL FFA ALEEV IETIEAGFMTKDLAACIKGLPNVQRSD
Sbjct: 301 ASIFAWTRGLAHRAKLDNNKELGFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQRSD 360
Query: 391 YLNTF 395
YLNTF
Sbjct: 361 YLNTF 365
>gb|ABD77223.1| isocitrate dehydrogenase 1 [Bos taurus]
Length = 367
Score = 740 bits (1910), Expect = 0.0, Method: Composition-based stats.
Identities = 351/366 (95%), Positives = 357/366 (97%)
Query: 31 IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQ 90
IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKK+NVGVKCATITPDEKRVEEFKLKQ
Sbjct: 1 IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQ 60
Query: 91 MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG 150
MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG
Sbjct: 61 MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG 120
Query: 151 KVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLS 210
KVEI+YTPSDG+ K YLVHNF E GGVAMGMYNQDKSIEDFAHSSFQMALSK WPLYLS
Sbjct: 121 KVEISYTPSDGSPKTVYLVHNFTESGGVAMGMYNQDKSIEDFAHSSFQMALSKNWPLYLS 180
Query: 211 TKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACK 270
TKNTILKKYDGRFKDIFQEIYDKQYKS+FEAQ IWYEHRLIDDMVAQAMKSEGGFIWACK
Sbjct: 181 TKNTILKKYDGRFKDIFQEIYDKQYKSEFEAQNIWYEHRLIDDMVAQAMKSEGGFIWACK 240
Query: 271 NYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI 330
NYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI
Sbjct: 241 NYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI 300
Query: 331 ASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSD 390
ASIFAWTRGLAHRAKLDNNKEL+FFA ALEEV IETIEAGFMTKDLAACIKGLPNVQRSD
Sbjct: 301 ASIFAWTRGLAHRAKLDNNKELSFFAKALEEVCIETIEAGFMTKDLAACIKGLPNVQRSD 360
Query: 391 YLNTFE 396
YLNTF+
Sbjct: 361 YLNTFD 366
>gb|ABD77207.1| isocitrate dehydrogenase 1 [Tamandua tetradactyla]
Length = 371
Score = 739 bits (1907), Expect = 0.0, Method: Composition-based stats.
Identities = 348/366 (95%), Positives = 358/366 (97%)
Query: 33 PYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMW 92
P+VELDLHSYDLGIENRDAT+DQVTKDAAEAIKK+NVG+KCATITPDEKRVEEFKLKQMW
Sbjct: 6 PHVELDLHSYDLGIENRDATHDQVTKDAAEAIKKYNVGIKCATITPDEKRVEEFKLKQMW 65
Query: 93 KSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKV 152
KSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKV
Sbjct: 66 KSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKV 125
Query: 153 EITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTK 212
E+ YTPSDGTQ +TYL+HNFEE GGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTK
Sbjct: 126 EMIYTPSDGTQNLTYLIHNFEECGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTK 185
Query: 213 NTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNY 272
NTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNY
Sbjct: 186 NTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNY 245
Query: 273 DGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIAS 332
DGDVQSDSVAQG+GSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRM+QKGQETSTNPIAS
Sbjct: 246 DGDVQSDSVAQGFGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMHQKGQETSTNPIAS 305
Query: 333 IFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYL 392
IFAWTRGLAHRAKLDNNKEL +FA ALEEV IETIE GFMTKDLAACIKGLPNVQRSDYL
Sbjct: 306 IFAWTRGLAHRAKLDNNKELGYFAKALEEVCIETIEFGFMTKDLAACIKGLPNVQRSDYL 365
Query: 393 NTFEFM 398
NTF FM
Sbjct: 366 NTFVFM 371
>gb|ABD77219.1| isocitrate dehydrogenase 1 [Canis familiaris]
Length = 362
Score = 738 bits (1905), Expect = 0.0, Method: Composition-based stats.
Identities = 351/361 (97%), Positives = 357/361 (98%)
Query: 36 ELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSP 95
ELDLHSYDLGIENRDATNDQVTKDAAEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSP
Sbjct: 1 ELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSP 60
Query: 96 NGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEIT 155
NGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEIT
Sbjct: 61 NGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEIT 120
Query: 156 YTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTI 215
YTPSDG++K+TYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTI
Sbjct: 121 YTPSDGSEKMTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTI 180
Query: 216 LKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 275
LKKYDGRFKDIFQEIYDKQYKSQFEAQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD
Sbjct: 181 LKKYDGRFKDIFQEIYDKQYKSQFEAQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGD 240
Query: 276 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFA 335
VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFA
Sbjct: 241 VQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFA 300
Query: 336 WTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTF 395
WTRGLAHRAKLDNNKEL+FFA ALEEV +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTF
Sbjct: 301 WTRGLAHRAKLDNNKELSFFAKALEEVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTF 360
Query: 396 E 396
E
Sbjct: 361 E 361
>gb|ABD77224.1| isocitrate dehydrogenase 1 [Balaenoptera physalus]
Length = 365
Score = 737 bits (1903), Expect = 0.0, Method: Composition-based stats.
Identities = 349/365 (95%), Positives = 355/365 (97%)
Query: 31 IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLKQ 90
IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKK+NVGVKCATITPDEKRVEEFKLKQ
Sbjct: 1 IFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKYNVGVKCATITPDEKRVEEFKLKQ 60
Query: 91 MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG 150
MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG
Sbjct: 61 MWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPG 120
Query: 151 KVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYLS 210
KVEI+YTPSDG+ K TYLVHNF EGGGVAMGMYNQDK+IEDFAHSSF MALSK WPLYLS
Sbjct: 121 KVEISYTPSDGSPKTTYLVHNFTEGGGVAMGMYNQDKAIEDFAHSSFLMALSKNWPLYLS 180
Query: 211 TKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQAMKSEGGFIWACK 270
TKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ IWYEHRLIDDMVAQAMKSEGGFIWACK
Sbjct: 181 TKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQNIWYEHRLIDDMVAQAMKSEGGFIWACK 240
Query: 271 NYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI 330
NYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI
Sbjct: 241 NYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPI 300
Query: 331 ASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLAACIKGLPNVQRSD 390
ASIFAWTRGLAHRAKLDNNK+L+FFA LEEV IETIEAGFMTKDLAACIKGLPNVQRSD
Sbjct: 301 ASIFAWTRGLAHRAKLDNNKDLSFFAKVLEEVCIETIEAGFMTKDLAACIKGLPNVQRSD 360
Query: 391 YLNTF 395
YLNT
Sbjct: 361 YLNTL 365
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|XP_001107627.1| PREDICTED: isocitrate dehydrogenase 1 (... 772 0.0
emb|CAG38738.1| IDH1 [Homo sapiens] 770 0.0
ref|NP_005887.2| isocitrate dehydrogenase 1 (NADP+), solubl... 769 0.0
sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytopl... 768 0.0
ref|XP_001141655.1| PREDICTED: isocitrate dehydrogenase 1 (... 768 0.0
sp|Q5R9C5|IDHC_PONPY Isocitrate dehydrogenase [NADP] cytopl... 768 0.0
sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytopl... 768 0.0
ref|NP_851355.2| isocitrate dehydrogenase 1 (NADP+), solubl... 768 0.0
ref|XP_850187.1| PREDICTED: similar to Isocitrate dehydroge... 768 0.0
ref|NP_001009276.1| cytosolic NADP-isocitrate dehydrogenase... 767 0.0
ref|NP_113698.1| isocitrate dehydrogenase 1 (NADP+), solubl... 767 0.0
gb|AAH93020.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 767 0.0
emb|CAD97653.1| hypothetical protein [Homo sapiens] >gi|117... 766 0.0
emb|CAB66637.1| hypothetical protein [Homo sapiens] >gi|117... 765 0.0
sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytopl... 765 0.0
ref|XP_001505172.1| PREDICTED: similar to Isocitrate dehydr... 764 0.0
emb|CAH91635.1| hypothetical protein [Pongo abelii] 764 0.0
sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytopl... 764 0.0
emb|CAH89719.1| hypothetical protein [Pongo abelii] 763 0.0
ref|NP_034627.3| isocitrate dehydrogenase 1 (NADP+), solubl... 763 0.0
gb|AAD02918.1| NADP-dependent isocitrate dehydrogenase [Hom... 763 0.0
dbj|BAE39644.1| unnamed protein product [Mus musculus] 763 0.0
dbj|BAC39792.1| unnamed protein product [Mus musculus] 762 0.0
gb|AAH88986.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 761 0.0
emb|CAG38553.1| IDH1 [Homo sapiens] 761 0.0
ref|XP_421965.2| PREDICTED: similar to cytosolic NADP-depen... 759 0.0
gb|ABU41004.1| isocitrate dehydrogenase 1 [Anser anser] 759 0.0
pdb|2CMJ|A Chain A, Crystal Structure Of Mouse Cytosolic Is... 756 0.0
ref|NP_001088022.1| hypothetical protein LOC494713 [Xenopus... 756 0.0
ref|XP_001365492.1| PREDICTED: similar to cytosolic NADP-de... 756 0.0
ref|XP_860821.1| PREDICTED: similar to Isocitrate dehydroge... 754 0.0
ref|XP_001511049.1| PREDICTED: similar to cytosolic NADP-de... 752 0.0
ref|XP_860853.1| PREDICTED: similar to Isocitrate dehydroge... 751 0.0
ref|XP_536192.2| PREDICTED: similar to isocitrate dehydroge... 737 0.0
emb|CAQ15240.1| isocitrate dehydrogenase 1 (NADP+), soluble... 734 0.0
ref|XP_001633903.1| predicted protein [Nematostella vectens... 733 0.0
ref|NP_786984.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 733 0.0
sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitoc... 733 0.0
ref|NP_958907.1| isocitrate dehydrogenase 1 (NADP+), solubl... 733 0.0
ref|XP_001369305.1| PREDICTED: hypothetical protein [Monode... 732 0.0
ref|NP_001026770.1| hypothetical protein LOC431056 [Gallus ... 732 0.0
sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitoc... 731 0.0
ref|NP_970434.1| isocitrate dehydrogenase [Bdellovibrio bac... 730 0.0
ref|NP_766599.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 730 0.0
ref|XP_001688948.1| AGAP006660-PA [Anopheles gambiae str. P... 729 0.0
emb|CAG02627.1| unnamed protein product [Tetraodon nigrovir... 728 0.0
gb|ACO14046.1| Isocitrate dehydrogenase, mitochondrial prec... 728 0.0
gb|ABE98244.1| mitochondrial isocitrate dehydrogenase 2-lik... 728 0.0
emb|CAM77136.1| Isocitrate/isopropylmalate dehydrogenase [M... 727 0.0
ref|NP_001014183.1| isocitrate dehydrogenase 2 (NADP+), mit... 727 0.0
ref|XP_510589.2| PREDICTED: isocitrate dehydrogenase 2 (NAD... 727 0.0
pdb|1LWD|A Chain A, Crystal Structure Of Nadp-Dependent Iso... 727 0.0
ref|XP_001841910.1| isocitrate dehydrogenase cytoplasmic [C... 726 0.0
sp|P33198|IDHP_PIG Isocitrate dehydrogenase [NADP], mitocho... 726 0.0
ref|XP_001095686.1| PREDICTED: isocitrate dehydrogenase 2 (... 726 0.0
ref|NP_955858.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 726 0.0
ref|NP_002159.2| isocitrate dehydrogenase 2 (NADP+), mitoch... 726 0.0
ref|NP_539708.1| isocitrate dehydrogenase [Brucella meliten... 725 0.0
emb|CAA53300.1| isocitrate dehydrogenase (NADP+) [Solanum t... 725 0.0
emb|CAA49208.1| isocitrate dehydrogenase (NADP+) [Homo sapi... 725 0.0
ref|NP_698203.1| isocitrate dehydrogenase [Brucella suis 13... 724 0.0
dbj|BAD96636.1| isocitrate dehydrogenase 2 (NADP+), mitocho... 724 0.0
gb|EAX02083.1| isocitrate dehydrogenase 2 (NADP+), mitochon... 723 0.0
ref|XP_001168316.1| PREDICTED: isocitrate dehydrogenase 2 (... 722 0.0
gb|EEJ98364.1| isocitrate dehydrogenase (NADP) [Thermomonos... 722 0.0
ref|ZP_01885694.1| isocitrate dehydrogenase [Pedobacter sp.... 722 0.0
dbj|BAC77065.1| NADP-specific isocitrate dehydrogenase [Lup... 722 0.0
ref|NP_001056381.1| Os05g0573200 [Oryza sativa (japonica cu... 721 0.0
sp|P50218|IDHC_TOBAC Isocitrate dehydrogenase [NADP] (Oxalo... 721 0.0
emb|CAG13105.1| unnamed protein product [Tetraodon nigrovir... 721 0.0
gb|AAC64182.1| NADP-dependent isocitrate dehydrogenase [Gly... 720 0.0
ref|NP_001043749.1| Os01g0654500 [Oryza sativa (japonica cu... 720 0.0
gb|AAB39248.1| NADP-isocitrate dehydrogenase [Eucalyptus gl... 720 0.0
ref|ZP_00056387.1| COG0538: Isocitrate dehydrogenases [Magn... 719 0.0
ref|XP_001778805.1| predicted protein [Physcomitrella paten... 719 0.0
ref|XP_001650675.1| nadp-specific isocitrate dehydrogenase ... 719 0.0
ref|ZP_02188085.1| Isocitrate dehydrogenase [alpha proteoba... 719 0.0
sp|P50217|IDHC_SOLTU Isocitrate dehydrogenase [NADP] (Oxalo... 719 0.0
ref|YP_419971.1| isocitrate dehydrogenase [Magnetospirillum... 719 0.0
ref|YP_677841.1| isocitrate dehydrogenase [Cytophaga hutchi... 718 0.0
ref|XP_001168291.1| PREDICTED: isocitrate dehydrogenase 2 (... 718 0.0
ref|NP_001080321.1| hypothetical protein LOC380013 [Xenopus... 718 0.0
emb|CAG02362.1| unnamed protein product [Tetraodon nigrovir... 717 0.0
ref|YP_290624.1| isocitrate dehydrogenase [Thermobifida fus... 717 0.0
ref|YP_001370537.1| isocitrate dehydrogenase, NADP-dependen... 716 0.0
sp|Q40345|IDHP_MEDSA Isocitrate dehydrogenase [NADP], chlor... 715 0.0
dbj|BAA34112.1| NADP specific isocitrate dehydrogenase [Dau... 715 0.0
ref|ZP_03891012.1| isocitrate dehydrogenase (NADP) [Geoderm... 715 0.0
ref|XP_968850.1| PREDICTED: similar to CG7176-PC, isoform C... 714 0.0
gb|ABA18651.1| cytosolic NADP+-isocitrate dehydrogenase [Po... 714 0.0
gb|AAD51361.1|AF176669_1 NADP-isocitrate dehydrogenase [Cit... 713 0.0
emb|CAA65503.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 713 0.0
ref|NP_385898.1| isocitrate dehydrogenase [Sinorhizobium me... 713 0.0
gb|ABK24873.1| unknown [Picea sitchensis] 713 0.0
gb|AAA33978.1| NADPH-specific isocitrate dehydrogenase 713 0.0
gb|AAL11503.1|AF367443_1 NADP-dependent isocitrate dehydrog... 713 0.0
emb|CAA73139.1| isocitrate dehydrogenase (NADP+) [Apium gra... 713 0.0
gb|AAT06312.1| isocitrate dehydrogenase [Rhizobium legumino... 713 0.0
ref|YP_001327198.1| isocitrate dehydrogenase [Sinorhizobium... 713 0.0
ref|ZP_02166681.1| isocitrate dehydrogenase [Hoeflea photot... 712 0.0
ref|YP_002826161.1| NADP isocitrate dehydrogenase [Rhizobiu... 712 0.0
ref|NP_001004799.1| MGC69505 protein [Xenopus tropicalis] >... 712 0.0
gb|AAF73472.1|AF268076_1 NADP-dependent isocitrate dehydrog... 712 0.0
ref|XP_001168261.1| PREDICTED: isocitrate dehydrogenase 2 (... 712 0.0
pir||S33612 isocitrate dehydrogenase (NADP) (EC 1.1.1.42) -... 712 0.0
ref|YP_768215.1| isocitrate dehydrogenase [Rhizobium legumi... 712 0.0
emb|CAA65504.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 712 0.0
ref|ZP_02295934.1| isocitrate dehydrogenase, NADP-dependent... 712 0.0
ref|NP_101923.1| isocitrate dehydrogenase [Mesorhizobium lo... 711 0.0
gb|EDT29808.1| isocitrate dehydrogenase, NADP-dependent [Ol... 711 0.0
ref|YP_673828.1| isocitrate dehydrogenase [Mesorhizobium sp... 711 0.0
ref|YP_706173.1| isocitrate dehydrogenase [Rhodococcus sp. ... 711 0.0
ref|XP_001778590.1| predicted protein [Physcomitrella paten... 711 0.0
dbj|BAE48792.1| NADP-isocitrate dehydrogenase [Codonopsis l... 711 0.0
ref|ZP_02858718.1| isocitrate dehydrogenase, NADP-dependent... 711 0.0
ref|NP_421325.1| isocitrate dehydrogenase [Caulobacter cres... 711 0.0
ref|XP_001608101.1| PREDICTED: similar to isocitrate dehydr... 711 0.0
dbj|BAA34113.1| NADP specific isocitrate dehydrogenase [Dau... 710 0.0
gb|ACO14957.1| Isocitrate dehydrogenase cytoplasmic [Caligu... 709 0.0
ref|NP_354851.2| isocitrate dehydrogenase [Agrobacterium tu... 709 0.0
ref|YP_002761841.1| NADP-dependent isocitrate dehydrogenase... 709 0.0
ref|XP_970446.1| PREDICTED: similar to isocitrate dehydroge... 709 0.0
ref|YP_001413846.1| isocitrate dehydrogenase, NADP-dependen... 709 0.0
ref|YP_425448.1| isocitrate dehydrogenase [Rhodospirillum r... 709 0.0
ref|NP_196963.2| isocitrate dehydrogenase, putative / NADP+... 709 0.0
ref|NP_001040134.1| isocitrate dehydrogenase [Bombyx mori] ... 709 0.0
prf||2211361A isocitrate dehydrogenase 709 0.0
gb|AAC52473.1| isocitrate dehydrogenase 709 0.0
gb|EAY99113.1| hypothetical protein OsI_020346 [Oryza sativ... 708 0.0
dbj|BAC77063.1| NADP-specific isocitrate dehydrogenase [Lup... 708 0.0
ref|XP_001698704.1| isocitrate dehydrogenase, NADP-dependen... 708 0.0
ref|ZP_03869030.1| isocitrate dehydrogenase (NADP) [Jonesia... 708 0.0
ref|ZP_02124492.1| Isocitrate dehydrogenase (NADP(+)) [Meth... 708 0.0
sp|Q06197|IDHC_SOYBN Isocitrate dehydrogenase [NADP] (Oxalo... 708 0.0
ref|YP_001685152.1| isocitrate dehydrogenase, NADP-dependen... 707 0.0
ref|YP_001524781.1| NADP-dependent isocitrate dehydrogenase... 707 0.0
emb|CAD24779.1| isocitrate dehydrogenase [Cucumis sativus] 707 0.0
emb|CAN72808.1| hypothetical protein [Vitis vinifera] >gi|1... 707 0.0
dbj|BAC77064.1| NADP-specific isocitrate dehydrogenase [Lup... 706 0.0
ref|XP_001176537.1| PREDICTED: similar to Isocitrate dehydr... 705 0.0
ref|YP_002783489.1| isocitrate dehydrogenase [Rhodococcus o... 705 0.0
ref|YP_001609735.1| NADP-dependent isocitrate dehydrogenase... 705 0.0
gb|ABI52605.1| isocitrate dehydrogenase [Gryllus firmus] 705 0.0
ref|ZP_03896321.1| isocitrate dehydrogenase (NADP) [Dyadoba... 705 0.0
ref|YP_001296741.1| isocitrate dehydrogenase [Flavobacteriu... 704 0.0
ref|NP_175836.1| ICDH; isocitrate dehydrogenase (NADP+) [Ar... 704 0.0
ref|YP_002765452.1| NADP-dependent isocitrate dehydrogenase... 704 0.0
gb|ABD77209.1| isocitrate dehydrogenase 1 [Rattus norvegicus] 704 0.0
ref|YP_872148.1| isocitrate dehydrogenase [Acidothermus cel... 704 0.0
gb|AAV33246.1| isocitrate dehydrogenase [Toxoplasma gondii] 704 0.0
gb|AAS49171.1| NADP-dependent isocitrate dehydrogenase [Pis... 704 0.0
ref|YP_001623415.1| isocitrate dehydrogenase (NADP) [Reniba... 704 0.0
gb|AAR05796.1| NADP+-isocitrate dehydrogenase [Pinus pinaster] 703 0.0
ref|YP_117132.1| isocitrate dehydrogenase [Nocardia farcini... 703 0.0
ref|YP_001769504.1| isocitrate dehydrogenase, NADP-dependen... 703 0.0
ref|XP_623673.2| PREDICTED: similar to Isocitrate dehydroge... 703 0.0
ref|YP_001538953.1| isocitrate dehydrogenase, NADP-dependen... 703 0.0
ref|YP_001419447.1| isocitrate dehydrogenase, NADP-dependen... 703 0.0
ref|YP_001160602.1| isocitrate dehydrogenase [Salinispora t... 702 0.0
ref|ZP_03819206.1| isocitrate dehydrogenase (NADP) [Actinos... 702 0.0
ref|XP_312860.4| AGAP003168-PA [Anopheles gambiae str. PEST... 702 0.0
ref|XP_821599.1| isocitrate dehydrogenase, putative [Trypan... 701 0.0
ref|ZP_00952302.1| isocitrate dehydrogenase [Oceanicaulis a... 701 0.0
ref|ZP_01546031.1| isocitrate dehydrogenase [Stappia aggreg... 701 0.0
ref|XP_001903959.1| unnamed protein product [Podospora anse... 700 0.0
ref|NP_176768.1| isocitrate dehydrogenase, putative / NADP+... 700 0.0
ref|ZP_01228834.1| NADP dependent isocitrate dehydrogenase ... 700 0.0
ref|ZP_01862723.1| isocitrate dehydrogenase [Erythrobacter ... 700 0.0
ref|ZP_01303522.1| isocitrate dehydrogenase, NADP-dependent... 700 0.0
ref|YP_001832264.1| isocitrate dehydrogenase, NADP-dependen... 700 0.0
ref|XP_001670101.1| Hypothetical protein CBG21657 [Caenorha... 700 0.0
emb|CAB87626.1| isocitrate dehydrogenase-like protein [Arab... 699 0.0
ref|NP_772387.1| isocitrate dehydrogenase [Bradyrhizobium j... 699 0.0
ref|XP_780121.1| PREDICTED: similar to cytosolic NADP-depen... 699 0.0
gb|ABD77208.1| isocitrate dehydrogenase 1 [Mus musculus] 699 0.0
ref|XP_001226620.1| conserved hypothetical protein [Chaetom... 699 0.0
ref|YP_001108727.1| isocitrate dehydrogenase [Saccharopolys... 699 0.0
ref|XP_001240510.1| isocitrate dehydrogenase NADP, mitochon... 699 0.0
gb|AAM13090.1| similar to NADP-specific isocitrate dehydrog... 699 0.0
ref|ZP_03813993.1| isocitrate dehydrogenase (NADP) [Beutenb... 699 0.0
ref|YP_682929.1| isocitrate dehydrogenase [Roseobacter deni... 698 0.0
ref|NP_001042583.1| Os01g0248400 [Oryza sativa (japonica cu... 698 0.0
emb|CAA63220.1| isocitrate dehydrogenase (NAD+) [Solanum tu... 698 0.0
gb|EAY58582.1| isocitrate dehydrogenase [NADP] icd1 [Mycoba... 698 0.0
emb|CAD24782.1| isocitrate dehydrogenase [Arabidopsis thali... 698 0.0
ref|XP_955850.1| hypothetical protein NCU03857 [Neurospora ... 698 0.0
gb|AAM65674.1| isocitrate dehydrogenase, putative [Arabidop... 698 0.0
ref|YP_032403.1| isocitrate dehydrogenase [Bartonella quint... 697 0.0
gb|AAT44354.1| isocitrate dehydrogenase [Crassostrea gigas] 697 0.0
ref|NP_217856.1| isocitrate dehydrogenase [Mycobacterium tu... 697 0.0
ref|YP_001849499.1| isocitrate dehydrogenase [NADP] Icd1 [M... 697 0.0
ref|YP_033790.1| isocitrate dehydrogenase [Bartonella hense... 697 0.0
ref|YP_617009.1| isocitrate dehydrogenase [Sphingopyxis ala... 696 0.0
ref|XP_001457045.1| hypothetical protein GSPATT00022820001 ... 696 0.0
ref|YP_756242.1| isocitrate dehydrogenase [Maricaulis maris... 696 0.0
ref|ZP_02955422.1| isocitrate dehydrogenase, NADP-dependent... 696 0.0
ref|YP_979491.1| isocitrate dehydrogenase [Mycobacterium bo... 696 0.0
ref|YP_001223282.1| isocitrate dehydrogenase [Clavibacter m... 696 0.0
ref|YP_496560.1| isocitrate dehydrogenase [Novosphingobium ... 696 0.0
ref|YP_001204807.1| isocitrate dehydrogenase [Bradyrhizobiu... 696 0.0
emb|CAO64975.1| unnamed protein product [Vitis vinifera] 696 0.0
ref|YP_001709366.1| isocitrate dehydrogenase [Clavibacter m... 696 0.0
ref|ZP_01440188.1| Isocitrate/isopropylmalate dehydrogenase... 696 0.0
ref|YP_001833636.1| isocitrate dehydrogenase, NADP-dependen... 695 0.0
ref|XP_001426548.1| hypothetical protein GSPATT00029781001 ... 695 0.0
ref|NP_001093090.1| NADPH-specific isocitrate dehydrogenase... 695 0.0
ref|NP_949171.1| isocitrate dehydrogenase [Rhodopseudomonas... 695 0.0
ref|NP_501665.1| F59B8.2 [Caenorhabditis elegans] >gi|38778... 695 0.0
gb|ABD77216.1| isocitrate dehydrogenase 1 [Aotus trivirgatus] 694 0.0
gb|ABD77215.1| isocitrate dehydrogenase 1 [Homo sapiens] 694 0.0
ref|XP_754749.1| isocitrate dehydrogenase Idp1 [Aspergillus... 694 0.0
gb|EDP52872.1| isocitrate dehydrogenase Idp1, putative [Asp... 694 0.0
ref|ZP_01046178.1| isocitrate dehydrogenase NADP-dependent ... 694 0.0
ref|YP_458429.1| isocitrate dehydrogenase [Erythrobacter li... 694 0.0
gb|AAI53922.1| Idh1 protein [Danio rerio] 694 0.0
ref|XP_001845030.1| isocitrate dehydrogenase [Culex pipiens... 693 0.0
ref|XP_001593497.1| hypothetical protein SS1G_04924 [Sclero... 693 0.0
ref|ZP_00964081.1| isocitrate dehydrogenase [Sulfitobacter ... 693 0.0
ref|ZP_01040029.1| isocitrate dehydrogenase [Erythrobacter ... 693 0.0
ref|ZP_02302766.1| isocitrate dehydrogenase, NADP-dependent... 693 0.0
ref|ZP_00954676.1| isocitrate dehydrogenase [Sulfitobacter ... 693 0.0
ref|YP_909639.1| isocitrate dehydrogenase [Bifidobacterium ... 692 0.0
ref|NP_001053269.1| Os04g0508200 [Oryza sativa (japonica cu... 692 0.0
ref|YP_487337.1| isocitrate dehydrogenase [Rhodopseudomonas... 692 0.0
ref|ZP_00206729.1| COG0538: Isocitrate dehydrogenases [Bifi... 692 0.0
sp|P50215|IDH_SPHYA Isocitrate dehydrogenase [NADP] (Oxalos... 691 0.0
ref|YP_001363715.1| isocitrate dehydrogenase, NADP-dependen... 691 0.0
ref|YP_989041.1| isocitrate dehydrogenase [Bartonella bacil... 691 0.0
ref|YP_062774.1| isocitrate dehydrogenase [Leifsonia xyli s... 691 0.0
ref|YP_001241304.1| isocitrate dehydrogenase [Bradyrhizobiu... 691 0.0
ref|YP_001758392.1| isocitrate dehydrogenase, NADP-dependen... 691 0.0
ref|YP_001233708.1| isocitrate dehydrogenase [Acidiphilium ... 691 0.0
ref|NP_696658.1| isocitrate dehydrogenase [Bifidobacterium ... 690 0.0
gb|ABO93633.1| isocitrate dehydrogenase 2 [Toxoplasma gondii] 690 0.0
ref|XP_451683.1| unnamed protein product [Kluyveromyces lac... 690 0.0
ref|YP_001168561.1| isocitrate dehydrogenase [Rhodobacter s... 690 0.0
ref|YP_001169228.1| isocitrate dehydrogenase [Rhodobacter s... 690 0.0
ref|YP_317907.1| isocitrate dehydrogenase [Nitrobacter wino... 690 0.0
ref|ZP_03977360.1| isocitrate dehydrogenase (NADP(+)) [Bifi... 690 0.0
emb|CAE04728.1| OSJNBa0043L24.16 [Oryza sativa (japonica cu... 690 0.0
ref|ZP_03922528.1| isocitrate dehydrogenase [Mobiluncus cur... 689 0.0
gb|ABD77211.1| isocitrate dehydrogenase 1 [Cavia porcellus] 689 0.0
ref|YP_576902.1| isocitrate dehydrogenase [Nitrobacter hamb... 689 0.0
ref|YP_568874.1| isocitrate dehydrogenase [Rhodopseudomonas... 689 0.0
ref|XP_001020930.2| dehydrogenase, isocitrate/isopropylmala... 689 0.0
gb|ABL97438.1| isocitrate dehydrogenase [uncultured marine ... 688 0.0
ref|XP_390523.1| hypothetical protein FG10347.1 [Gibberella... 688 0.0
gb|ABD77213.1| isocitrate dehydrogenase 1 [Oryctolagus cuni... 688 0.0
emb|CAH67563.1| OSIGBa0101P20.6 [Oryza sativa (indica culti... 688 0.0
ref|YP_531457.1| isocitrate dehydrogenase [Rhodopseudomonas... 688 0.0
ref|YP_001043974.1| isocitrate dehydrogenase [Rhodobacter s... 688 0.0
ref|YP_001260963.1| isocitrate dehydrogenase [Sphingomonas ... 688 0.0
ref|XP_001462393.1| hypothetical protein GSPATT00027349001 ... 688 0.0
ref|YP_001042101.1| isocitrate dehydrogenase [Rhodobacter s... 688 0.0
gb|ABK25438.1| unknown [Picea sitchensis] 687 0.0
ref|XP_001454244.1| hypothetical protein GSPATT00020509001 ... 687 0.0
ref|YP_353519.1| isocitrate dehydrogenase [Rhodobacter spha... 687 0.0
ref|YP_780531.1| isocitrate dehydrogenase [Rhodopseudomonas... 686 0.0
ref|XP_001384028.1| Isocitrate dehydrogenase [NADP], mitoch... 686 0.0
ref|NP_729367.1| Isocitrate dehydrogenase CG7176-PD, isofor... 686 0.0
ref|XP_001837820.1| hypothetical protein CC1G_11465 [Coprin... 686 0.0
ref|XP_001676039.1| Hypothetical protein CBG17397 [Caenorha... 686 0.0
ref|ZP_01018081.1| isocitrate dehydrogenase [Parvularcula b... 686 0.0
gb|AAK76730.1| mitochondrial NADP-dependent isocitrate dehy... 686 0.0
ref|XP_001878769.1| predicted protein [Laccaria bicolor S23... 686 0.0
ref|YP_351602.1| isocitrate dehydrogenase [Rhodobacter spha... 686 0.0
ref|NP_509875.1| C34F6.8 [Caenorhabditis elegans] >gi|38747... 685 0.0
ref|NP_729366.1| Isocitrate dehydrogenase CG7176-PB, isofor... 685 0.0
ref|ZP_01157336.1| isocitrate dehydrogenase [Oceanicola gra... 685 0.0
ref|YP_759895.1| isocitrate dehydrogenase [Hyphomonas neptu... 685 0.0
gb|ABD77222.1| isocitrate dehydrogenase 1 [Diceros bicornis] 685 0.0
sp|P79089|IDHP_ASPNG Isocitrate dehydrogenase [NADP], mitoc... 684 0.0
ref|NP_652044.1| Isocitrate dehydrogenase CG7176-PC, isofor... 684 0.0
ref|XP_504978.1| hypothetical protein [Yarrowia lipolytica]... 684 0.0
gb|ABD77217.1| isocitrate dehydrogenase 1 [Tupaia glis] 684 0.0
ref|XP_001354101.1| GA20156-PA [Drosophila pseudoobscura] >... 684 0.0
ref|ZP_02963068.1| isocitrate dehydrogenase [Bifidobacteriu... 684 0.0
ref|NP_729368.1| Isocitrate dehydrogenase CG7176-PA, isofor... 684 0.0
ref|ZP_00960755.1| Isocitrate dehydrogenase [Roseovarius nu... 684 0.0
ref|NP_962389.1| isocitrate dehydrogenase [Mycobacterium av... 683 0.0
ref|ZP_03993927.1| isocitrate dehydrogenase [Mobiluncus mul... 683 0.0
ref|ZP_01751534.1| isocitrate dehydrogenase [Roseobacter sp... 683 0.0
ref|XP_001528456.1| isocitrate dehydrogenase, mitochondrial... 682 0.0
ref|YP_001601185.1| Isocitrate dehydrogenase [Gluconacetoba... 682 0.0
gb|ABD77223.1| isocitrate dehydrogenase 1 [Bos taurus] 682 0.0
gb|ABF20272.1| mitochondrial isocitrate dehydrogenase [Leis... 682 0.0
ref|XP_459772.1| hypothetical protein DEHA0E11286g [Debaryo... 681 0.0
gb|ABD77221.1| isocitrate dehydrogenase 1 [Ceratotherium si... 681 0.0
ref|ZP_01130474.1| isocitrate dehydrogenase [marine actinob... 681 0.0
ref|XP_367343.2| hypothetical protein MGG_07268 [Magnaporth... 681 0.0
ref|XP_001400371.1| precursor of mitochondrial isocitrate d... 680 0.0
ref|ZP_02981592.1| isocitrate dehydrogenase, NADP-dependent... 680 0.0
ref|YP_883449.1| isocitrate dehydrogenase [Mycobacterium av... 680 0.0
ref|XP_001484278.1| isocitrate dehydrogenase, mitochondrial... 680 0.0
ref|XP_001634205.1| predicted protein [Nematostella vectens... 679 0.0
gb|ABD77207.1| isocitrate dehydrogenase 1 [Tamandua tetrada... 679 0.0
ref|XP_710919.1| NADP-specific isocitrate dehydrogenase [Ca... 679 0.0
gb|ABF20244.1| mitochondrial isocitrate dehydrogenase [Leis... 679 0.0
ref|XP_001463680.1| isocitrate dehydrogenase [NADP], mitoch... 679 0.0
gb|ABD77210.1| isocitrate dehydrogenase 1 [Mesocricetus aur... 679 0.0
Sequences not found previously or not previously below threshold:
>ref|XP_001107627.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 1
[Macaca mulatta]
ref|XP_001107810.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 2
[Macaca mulatta]
ref|XP_001107875.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 3
[Macaca mulatta]
ref|XP_001107934.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 4
[Macaca mulatta]
ref|XP_001107992.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 5
[Macaca mulatta]
Length = 414
Score = 772 bits (1995), Expect = 0.0, Method: Composition-based stats.
Identities = 410/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVE+QGDEMTRIIWELIKEKLIFPYVELDL SYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVELQGDEMTRIIWELIKEKLIFPYVELDLQSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAG38738.1| IDH1 [Homo sapiens]
Length = 414
Score = 770 bits (1988), Expect = 0.0, Method: Composition-based stats.
Identities = 413/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVE+TYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>ref|NP_005887.2| isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens]
sp|O75874|IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
pdb|1T09|A Chain A, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex Nadp
pdb|1T09|B Chain B, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex Nadp
pdb|1T0L|A Chain A, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|B Chain B, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|C Chain C, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|D Chain D, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
gb|AAD29284.1|AF113917_1 NADP+-dependent isocitrate dehydrogenase [Homo sapiens]
gb|AAH12846.1| IDH1 protein [Homo sapiens]
emb|CAG46496.1| IDH1 [Homo sapiens]
gb|AAX93221.1| unknown [Homo sapiens]
gb|EAW70439.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|EAW70441.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|EAW70442.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|ABM82361.1| isocitrate dehydrogenase 1 (NADP+), soluble [synthetic construct]
gb|ABW03396.1| isocitrate dehydrogenase 1 (NADP+), soluble [synthetic construct]
Length = 414
Score = 769 bits (1986), Expect = 0.0, Method: Composition-based stats.
Identities = 414/414 (100%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02924.1| cytosolic NADP-dependent isocitrate dehydrogenase [Microtus
mexicanus]
Length = 414
Score = 768 bits (1985), Expect = 0.0, Method: Composition-based stats.
Identities = 397/414 (95%), Positives = 407/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEIT+TP DG+QKVTYLVH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITFTPKDGSQKVTYLVHSFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAW+RGLAHRA+LDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>ref|XP_001141655.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 1
[Pan troglodytes]
ref|XP_001141734.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 2
[Pan troglodytes]
ref|XP_001141810.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 3
[Pan troglodytes]
ref|XP_001141879.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 4
[Pan troglodytes]
ref|XP_001141947.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 5
[Pan troglodytes]
ref|XP_001142041.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 6
[Pan troglodytes]
ref|XP_001142113.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 7
[Pan troglodytes]
ref|XP_001142197.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 8
[Pan troglodytes]
Length = 414
Score = 768 bits (1985), Expect = 0.0, Method: Composition-based stats.
Identities = 412/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKRYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>sp|Q5R9C5|IDHC_PONPY Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
Length = 414
Score = 768 bits (1984), Expect = 0.0, Method: Composition-based stats.
Identities = 411/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVS+ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02925.1| cytosolic NADP-dependent isocitrate dehydrogenase [Microtus
ochrogaster]
Length = 414
Score = 768 bits (1983), Expect = 0.0, Method: Composition-based stats.
Identities = 398/414 (96%), Positives = 407/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DG+QKVTYLVH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHSFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAW+RGLAHRA+LDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>ref|NP_851355.2| isocitrate dehydrogenase 1 (NADP+), soluble [Bos taurus]
gb|AAI03369.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Bos taurus]
Length = 414
Score = 768 bits (1983), Expect = 0.0, Method: Composition-based stats.
Identities = 396/414 (95%), Positives = 404/414 (97%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEI+YTPSDG+ K YLVHNF E GGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKS+FE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL++KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAKL 414
>ref|XP_850187.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 2 [Canis familiaris]
ref|XP_536047.2| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 1 [Canis familiaris]
Length = 414
Score = 768 bits (1983), Expect = 0.0, Method: Composition-based stats.
Identities = 401/414 (96%), Positives = 408/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDG++K+TYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL IKLAQAKL
Sbjct: 361 EVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL 414
>ref|NP_001009276.1| cytosolic NADP-isocitrate dehydrogenase [Ovis aries]
sp|Q6XUZ5|IDHC_SHEEP Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAP41947.1| cytosolic NADP-isocitrate dehydrogenase [Ovis aries]
Length = 414
Score = 767 bits (1982), Expect = 0.0, Method: Composition-based stats.
Identities = 394/414 (95%), Positives = 401/414 (96%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS KI GGSVVEMQGDEMTRIIWELIKEKLIFPYV+LDLHSYDL IENRDATNDQVTKDA
Sbjct: 1 MSHKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVDLDLHSYDLSIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEI YTPSDG+ K YLVHNF E GGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEICYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GM+NQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMFNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL++KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAKL 414
>ref|NP_113698.1| isocitrate dehydrogenase 1 (NADP+), soluble [Rattus norvegicus]
sp|P41562|IDHC_RAT Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAA59356.1| cytosolic NADP-dependent isocitrate dehydrogenase
gb|EDL98861.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98863.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98864.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98865.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
Length = 414
Score = 767 bits (1982), Expect = 0.0, Method: Composition-based stats.
Identities = 399/414 (96%), Positives = 408/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DG+QKVTYLVH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKS+FE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSKFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>gb|AAH93020.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens]
Length = 414
Score = 767 bits (1982), Expect = 0.0, Method: Composition-based stats.
Identities = 413/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAE+AHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAESAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAD97653.1| hypothetical protein [Homo sapiens]
emb|CAL38069.1| hypothetical protein [synthetic construct]
emb|CAL37462.1| hypothetical protein [synthetic construct]
Length = 414
Score = 766 bits (1978), Expect = 0.0, Method: Composition-based stats.
Identities = 412/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHN E GGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAB66637.1| hypothetical protein [Homo sapiens]
emb|CAL37490.1| hypothetical protein [synthetic construct]
Length = 414
Score = 765 bits (1976), Expect = 0.0, Method: Composition-based stats.
Identities = 412/414 (99%), Positives = 413/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWV+PIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD34457.1|AF136009_1 cytosolic NADP+-dependent isocitrate dehydrogenase [Bos taurus]
Length = 414
Score = 765 bits (1975), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 403/414 (97%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEI+YTPSDG+ K YLVHNF E GGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKS+FE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQET TNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETLTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL++KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAKL 414
>ref|XP_001505172.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Cytosolic NADP-isocitrate dehydrogenase)
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) [Equus caballus]
Length = 414
Score = 764 bits (1974), Expect = 0.0, Method: Composition-based stats.
Identities = 400/414 (96%), Positives = 408/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFP+VELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPHVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPG+VEITYTPSDG+QK TYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGRVEITYTPSDGSQKRTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQY+SQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYRSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELGFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 DVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAH91635.1| hypothetical protein [Pongo abelii]
Length = 414
Score = 764 bits (1973), Expect = 0.0, Method: Composition-based stats.
Identities = 409/414 (98%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKD FQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDTFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPI SIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIVSIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVS+ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02919.1| NADP-dependent isocitrate dehydrogenase [Mus musculus]
Length = 414
Score = 764 bits (1973), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 405/414 (97%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ I YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQNICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>emb|CAH89719.1| hypothetical protein [Pongo abelii]
Length = 414
Score = 763 bits (1972), Expect = 0.0, Method: Composition-based stats.
Identities = 409/414 (98%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWE IKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWEQIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVS+ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA AKL
Sbjct: 361 EVSVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLALAKL 414
>ref|NP_034627.3| isocitrate dehydrogenase 1 (NADP+), soluble [Mus musculus]
ref|NP_001104790.1| isocitrate dehydrogenase 1 (NADP+), soluble [Mus musculus]
dbj|BAE36075.1| unnamed protein product [Mus musculus]
dbj|BAE30207.1| unnamed protein product [Mus musculus]
dbj|BAE39299.1| unnamed protein product [Mus musculus]
dbj|BAE34873.1| unnamed protein product [Mus musculus]
dbj|BAE28720.1| unnamed protein product [Mus musculus]
gb|EDL00223.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Mus
musculus]
gb|EDL00225.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Mus
musculus]
Length = 414
Score = 763 bits (1971), Expect = 0.0, Method: Composition-based stats.
Identities = 396/414 (95%), Positives = 406/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>gb|AAD02918.1| NADP-dependent isocitrate dehydrogenase [Homo sapiens]
Length = 414
Score = 763 bits (1971), Expect = 0.0, Method: Composition-based stats.
Identities = 411/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILK YDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKIYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTN IASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNLIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACI+GLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIRGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>dbj|BAE39644.1| unnamed protein product [Mus musculus]
Length = 414
Score = 763 bits (1970), Expect = 0.0, Method: Composition-based stats.
Identities = 396/414 (95%), Positives = 406/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIKGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>dbj|BAC39792.1| unnamed protein product [Mus musculus]
Length = 422
Score = 762 bits (1968), Expect = 0.0, Method: Composition-based stats.
Identities = 394/413 (95%), Positives = 405/413 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQA+
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAQ 413
>gb|AAH88986.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Mus musculus]
Length = 414
Score = 761 bits (1967), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 406/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEA+KK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEALKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>emb|CAG38553.1| IDH1 [Homo sapiens]
Length = 414
Score = 761 bits (1966), Expect = 0.0, Method: Composition-based stats.
Identities = 411/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWV+PIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTK LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKGLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>ref|XP_421965.2| PREDICTED: similar to cytosolic NADP-dependent isocitrate
dehydrogenase [Gallus gallus]
Length = 415
Score = 759 bits (1961), Expect = 0.0, Method: Composition-based stats.
Identities = 369/410 (90%), Positives = 392/410 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTR+IWELIKEKLIFPYV+LDLHSYDLGIE+RDATND+VT +A
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIEHRDATNDKVTVEA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK++VG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYHVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPI+IGRHAYGDQYRATDFVVPGPGKVE+TYTP DG + VTYLVHNFE GGVAM
Sbjct: 121 VSGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEMTYTPGDGGKPVTYLVHNFESCGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI+DFAHSSFQMALSKGWPLY+STKNTILK+YDGRFKDIFQEIYD++YKSQFE
Sbjct: 181 GMYNLDQSIKDFAHSSFQMALSKGWPLYMSTKNTILKRYDGRFKDIFQEIYDREYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQA+KSEGGF+WACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAWTRGLAHRAKLDNN L FA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWTRGLAHRAKLDNNTSLKTFATALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA 410
EV IETIE+GFMTKDLAACIKGLPNV RSDYLNTFEFMDKL NLK KLA
Sbjct: 361 EVCIETIESGFMTKDLAACIKGLPNVTRSDYLNTFEFMDKLAANLKGKLA 410
>gb|ABU41004.1| isocitrate dehydrogenase 1 [Anser anser]
Length = 415
Score = 759 bits (1961), Expect = 0.0, Method: Composition-based stats.
Identities = 369/410 (90%), Positives = 393/410 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTR+IWELIKEKLIFPYV+LDLHSYDLGIE+RDATND+VT +A
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIEHRDATNDKVTVEA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK++VG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYHVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPI+IGRHAYGDQYRATDFVVPGPGKVE+TYTP DG + VTYLVHNFE GGVAM
Sbjct: 121 VSGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEMTYTPGDGGKPVTYLVHNFESCGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GM+N D+SI+DFAHSSFQMALSKGWPLY+STKNTILK+YDGRFKDIFQEIYD++YKSQFE
Sbjct: 181 GMFNLDQSIKDFAHSSFQMALSKGWPLYMSTKNTILKRYDGRFKDIFQEIYDREYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQA+KSEGGF+WACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAWTRGLAHRAKLDNN L FA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWTRGLAHRAKLDNNTSLKTFAAALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA 410
EV IETIE+GFMTKDLAACIKGLPNV RSDYLNTFEFMDKL ENLK KLA
Sbjct: 361 EVCIETIESGFMTKDLAACIKGLPNVTRSDYLNTFEFMDKLAENLKGKLA 410
>pdb|2CMJ|A Chain A, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase
pdb|2CMJ|B Chain B, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase
pdb|2CMV|A Chain A, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase Complexed With Cadmium And Citrate
pdb|2CMV|B Chain B, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase Complexed With Cadmium And Citrate
Length = 410
Score = 756 bits (1954), Expect = 0.0, Method: Composition-based stats.
Identities = 392/410 (95%), Positives = 401/410 (97%)
Query: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDAAEA
Sbjct: 1 KIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEA 60
Query: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
IKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 61 IKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 120
Query: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAMGMY
Sbjct: 121 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAMGMY 180
Query: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQK 243
NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFEAQ
Sbjct: 181 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQN 240
Query: 244 IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTV 303
I YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDGKTV
Sbjct: 241 ICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTV 300
Query: 304 EAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVS 363
EAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE+V
Sbjct: 301 EAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVC 360
Query: 364 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAK
Sbjct: 361 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAK 410
>ref|NP_001088022.1| hypothetical protein LOC494713 [Xenopus laevis]
gb|AAH82651.1| LOC494713 protein [Xenopus laevis]
Length = 415
Score = 756 bits (1953), Expect = 0.0, Method: Composition-based stats.
Identities = 363/410 (88%), Positives = 391/410 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI+GGSVVEMQGDEMTR+IW+LIKEKLI PYVELDLHSYDLG+ENRDAT+DQVT DA
Sbjct: 1 MSKKINGGSVVEMQGDEMTRVIWDLIKEKLILPYVELDLHSYDLGMENRDATDDQVTVDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVG+KCATITPDEKRVEEF LKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEKRVEEFNLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGW+KPIIIGRHAYGDQYRATDFVVPGPGKVEI++TP DG + + Y++HNFE+ GGVA+
Sbjct: 121 VSGWIKPIIIGRHAYGDQYRATDFVVPGPGKVEISFTPKDGGEAIKYVIHNFEDCGGVAL 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI DFAHSSFQMALSK WPLY+STKNTILK+YDGRFKDIFQEIY+K+YKSQFE
Sbjct: 181 GMYNTDQSIRDFAHSSFQMALSKSWPLYMSTKNTILKRYDGRFKDIFQEIYEKEYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 ENKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAW+RGL HRAKLDNN+EL FA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLDHRAKLDNNQELKNFATALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA 410
EV IETIEAGFMTKDLAACIKGLPNVQR DYL+TFEFMDKLGENL++KLA
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRGDYLSTFEFMDKLGENLQLKLA 410
>ref|XP_001365492.1| PREDICTED: similar to cytosolic NADP-dependent isocitrate
dehydrogenase [Monodelphis domestica]
Length = 414
Score = 756 bits (1952), Expect = 0.0, Method: Composition-based stats.
Identities = 369/414 (89%), Positives = 397/414 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI+GGSVVEMQGDEMTR+IW+LIK+KLIFPYV LDLHSYDLGIE+RD T+DQVT DA
Sbjct: 1 MSQKINGGSVVEMQGDEMTRVIWDLIKQKLIFPYVNLDLHSYDLGIEHRDETDDQVTIDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPI+IGRHAYGDQYRATDFVVPGPGKVEI+YTP DG++ VTYL+HNFE+ GGVAM
Sbjct: 121 VNGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEISYTPRDGSKTVTYLIHNFEDCGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI DFAHSSFQMAL+KGWPLY+STKNTILKKYDGRFKDIFQ+IYD YKS+FE
Sbjct: 181 GMYNLDQSIMDFAHSSFQMALTKGWPLYMSTKNTILKKYDGRFKDIFQKIYDTHYKSKFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQA+KSEGGF+WACKNYDGDVQSDS+AQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSIAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLD+NKEL FA LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDDNKELGTFATILE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIE+GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKL ENLK KLAQAKL
Sbjct: 361 EVCIETIESGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLAENLKAKLAQAKL 414
>ref|XP_860821.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 4 [Canis familiaris]
Length = 415
Score = 754 bits (1948), Expect = 0.0, Method: Composition-based stats.
Identities = 395/415 (95%), Positives = 404/415 (97%), Gaps = 1/415 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFE-EGGGVA 179
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDG++K+TYL+ +GGGVA
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYLIQVLSFKGGGVA 180
Query: 180 MGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQF 239
MGMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQF
Sbjct: 181 MGMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQF 240
Query: 240 EAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPD 299
EAQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPD
Sbjct: 241 EAQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPD 300
Query: 300 GKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANAL 359
GKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA AL
Sbjct: 301 GKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKAL 360
Query: 360 EEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EEV +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL IKLAQAKL
Sbjct: 361 EEVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL 415
>ref|XP_001511049.1| PREDICTED: similar to cytosolic NADP-dependent isocitrate
dehydrogenase [Ornithorhynchus anatinus]
Length = 415
Score = 752 bits (1942), Expect = 0.0, Method: Composition-based stats.
Identities = 374/415 (90%), Positives = 396/415 (95%), Gaps = 1/415 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS KI GGSVVEMQGDEMTR+IWELIKEKLIFPYV+LDLHSYDLGIENRDATND+VT +A
Sbjct: 1 MSSKICGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIENRDATNDKVTSEA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVP PGKVE+ YTP DG + VTYLVHNFE GGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPRPGKVEMVYTPQDGGKAVTYLVHNFEAGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI DFAHSSFQMALSK WPLY+STKNTILK+YDGRFKDIFQEIY+KQY+S+FE
Sbjct: 181 GMYNLDQSIRDFAHSSFQMALSKSWPLYMSTKNTILKRYDGRFKDIFQEIYEKQYRSKFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRH+RM+QKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+ FA LE
Sbjct: 301 KTVEAEAAHGTVTRHFRMHQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSTFATTLE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA-QAKL 414
+V +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLA QAKL
Sbjct: 361 DVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLASQAKL 415
>ref|XP_860853.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 5 [Canis familiaris]
Length = 408
Score = 751 bits (1940), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 402/414 (97%), Gaps = 6/414 (1%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDG++K+TYL GGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYL------GGGVAM 174
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 175 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 234
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 235 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 294
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 295 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 354
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL IKLAQAKL
Sbjct: 355 EVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL 408
>ref|XP_536192.2| PREDICTED: similar to isocitrate dehydrogenase 2 (NADP+),
mitochondrial [Canis familiaris]
Length = 517
Score = 737 bits (1904), Expect = 0.0, Method: Composition-based stats.
Identities = 284/410 (69%), Positives = 331/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 109 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 168
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 169 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 228
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G +I ++P DG+ + V+NF GGGV MGM
Sbjct: 229 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKIIFSPKDGSGAKEWEVYNFP-GGGVGMGM 287
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI++K YK+ F+
Sbjct: 288 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKN 347
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 348 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 407
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 408 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 467
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
++T+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L Q
Sbjct: 468 CVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKNNLDKALGQ 517
>emb|CAQ15240.1| isocitrate dehydrogenase 1 (NADP+), soluble [Danio rerio]
Length = 429
Score = 734 bits (1896), Expect = 0.0, Method: Composition-based stats.
Identities = 344/415 (82%), Positives = 383/415 (92%), Gaps = 1/415 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GSVVEMQGDEMTR+IWELIKEKLIFPY+ELDLHSYDLG+ENRDAT+D+VT +A
Sbjct: 15 MSQKIKAGSVVEMQGDEMTRVIWELIKEKLIFPYLELDLHSYDLGMENRDATDDKVTVEA 74
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEA++++NVG+KCATITPDEKRVEEFKLKQMW+SPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 75 AEAVRRYNVGIKCATITPDEKRVEEFKLKQMWRSPNGTIRNILGGTVFREAIICKNIPRL 134
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V GW+KPIIIGRHA+GDQY+ATDFVVPGPG VE+TY P +G + + ++VH+FE GGVA+
Sbjct: 135 VPGWIKPIIIGRHAHGDQYKATDFVVPGPGTVEMTYKPKNGGETLKFVVHDFEGTGGVAL 194
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN DKSI DFAHSSFQM L+KGWP+YLSTKNTILKKYDGRFKDIFQEIYDK+YK+++E
Sbjct: 195 GMYNTDKSIRDFAHSSFQMGLNKGWPMYLSTKNTILKKYDGRFKDIFQEIYDKEYKAKYE 254
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 255 AMGIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 314
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
+TVEAEAAHGTVTRHYRM+Q+G+ETSTNPIASIFAWTRGL HRA+LD N EL FA ALE
Sbjct: 315 RTVEAEAAHGTVTRHYRMHQQGKETSTNPIASIFAWTRGLLHRAELDKNAELRVFAEALE 374
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL-AQAKL 414
V +ETIEAGFMTKDLA CIKG+ V RSDYLNTFEF+DKL ENLKIKL +Q KL
Sbjct: 375 VVCVETIEAGFMTKDLAICIKGMSGVTRSDYLNTFEFLDKLAENLKIKLSSQPKL 429
>ref|XP_001633903.1| predicted protein [Nematostella vectensis]
gb|EDO41840.1| predicted protein [Nematostella vectensis]
Length = 411
Score = 733 bits (1894), Expect = 0.0, Method: Composition-based stats.
Identities = 321/408 (78%), Positives = 359/408 (87%), Gaps = 1/408 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
M+K G VVEMQGDEMTRIIWELIKEKLIFPYV+++L SYDL IENRDATNDQVT DA
Sbjct: 1 MAKIK-AGPVVEMQGDEMTRIIWELIKEKLIFPYVDMELKSYDLSIENRDATNDQVTIDA 59
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
A AIK+ +VG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 60 AAAIKQCHVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRL 119
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VS W KPIIIGRHA+ DQY+ATDFVVPGPGKVEI Y+P+DG + + Y V+ F++GGGV M
Sbjct: 120 VSPWTKPIIIGRHAHADQYKATDFVVPGPGKVEIVYSPADGGEPIKYTVNEFKDGGGVTM 179
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GM+N D SI FAHSSFQ AL K +PLY+STKNTILKKYDGRFKDIFQEIY+++YKS+FE
Sbjct: 180 GMFNTDVSIRAFAHSSFQYALDKKYPLYMSTKNTILKKYDGRFKDIFQEIYEQEYKSKFE 239
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
IWYEHRLIDDMVA A+K+EGGFIWACKNYDGDVQSDSVAQG+GSLGMMTSVLVCPDG
Sbjct: 240 ESNIWYEHRLIDDMVAFALKTEGGFIWACKNYDGDVQSDSVAQGFGSLGMMTSVLVCPDG 299
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVE+EAAHGTVTRHYRM+Q+G+ETSTNP+ASIFAWTRGL HRAKLD+N L + LE
Sbjct: 300 KTVESEAAHGTVTRHYRMHQQGKETSTNPVASIFAWTRGLMHRAKLDDNAALLDYCKNLE 359
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIK 408
V IETIE+G MTKDLA CIKG+ NV R DYLNTFEF+DK+ ENL K
Sbjct: 360 AVCIETIESGAMTKDLAGCIKGISNVTRPDYLNTFEFLDKIAENLAKK 407
>ref|NP_786984.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Bos taurus]
emb|CAA49207.1| isocitrate dehydrogenase (NADP+) [Bos taurus]
Length = 452
Score = 733 bits (1894), Expect = 0.0, Method: Composition-based stats.
Identities = 283/410 (69%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQ I++K YK++F+
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDKH 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L Q
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGQ 451
>sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAI02510.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Bos taurus]
Length = 452
Score = 733 bits (1893), Expect = 0.0, Method: Composition-based stats.
Identities = 283/410 (69%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQ I++K YK++F+
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDKH 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L Q
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGQ 451
>ref|NP_958907.1| isocitrate dehydrogenase 1 (NADP+), soluble [Danio rerio]
gb|AAH46894.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Danio rerio]
gb|AAI65569.1| Idh1 protein [synthetic construct]
Length = 429
Score = 733 bits (1892), Expect = 0.0, Method: Composition-based stats.
Identities = 343/415 (82%), Positives = 383/415 (92%), Gaps = 1/415 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+K+ GSVVEMQGDEMTR+IWELIKEKLIFPY+ELDLHSYDLG+ENRDAT+D+VT +A
Sbjct: 15 MSQKVKAGSVVEMQGDEMTRVIWELIKEKLIFPYLELDLHSYDLGMENRDATDDKVTVEA 74
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEA++++NVG+KCATITPDEKRVEEFKLKQMW+SPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 75 AEAVRRYNVGIKCATITPDEKRVEEFKLKQMWRSPNGTIRNILGGTVFREAIICKNIPRL 134
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V GW+KPIIIGRHA+GDQY+ATDFVVPGPG VE+TY P +G + + ++VH+FE GGVA+
Sbjct: 135 VPGWIKPIIIGRHAHGDQYKATDFVVPGPGTVEMTYKPKNGGETLKFVVHDFEGTGGVAL 194
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN DKSI DFAHSSFQM L+KGWP+YLSTKNTILKKYDGRFKDIFQEIYDK+YK+++E
Sbjct: 195 GMYNTDKSIRDFAHSSFQMGLNKGWPMYLSTKNTILKKYDGRFKDIFQEIYDKEYKAKYE 254
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 255 AMGIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 314
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
+TVEAEAAHGTVTRHYRM+Q+G+ETSTNPIASIFAWTRGL HRA+LD N EL FA ALE
Sbjct: 315 RTVEAEAAHGTVTRHYRMHQQGKETSTNPIASIFAWTRGLLHRAELDKNAELRVFAEALE 374
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKL-AQAKL 414
V +ETIEAGFMTKDLA CIKG+ V RSDYLNTFEF+DKL ENLKIKL +Q KL
Sbjct: 375 VVCVETIEAGFMTKDLAICIKGMSGVTRSDYLNTFEFLDKLAENLKIKLSSQPKL 429
>ref|XP_001369305.1| PREDICTED: hypothetical protein [Monodelphis domestica]
Length = 455
Score = 732 bits (1891), Expect = 0.0, Method: Composition-based stats.
Identities = 282/410 (68%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ +RD T+DQVT D+A
Sbjct: 46 RIKVDKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPHRDQTDDQVTIDSAL 105
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 106 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 165
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW +PI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 166 GWTRPITIGRHAHGDQYKATDFVVDKAGTFKMVFTPKDGSGAKEWEVYNFP-AGGVGMGM 224
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI+DK YK+ F+
Sbjct: 225 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 284
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 285 KIWYEHRLIDDMVAQVLKSNGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 344
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 345 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIKFAQTLEKV 404
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
++T+E+G MTKDLA CI GL NV+ YLNT +F+D + NL L Q
Sbjct: 405 CVQTVESGAMTKDLAGCIHGLSNVKLNEHYLNTGDFLDTIKNNLDKALGQ 454
>ref|NP_001026770.1| hypothetical protein LOC431056 [Gallus gallus]
emb|CAG31511.1| hypothetical protein [Gallus gallus]
Length = 452
Score = 732 bits (1890), Expect = 0.0, Method: Composition-based stats.
Identities = 282/410 (68%), Positives = 328/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW IKEKLI P V++ L +DLG+ +RD T+DQVT D+A
Sbjct: 43 RIKVANPVVEMDGDEMTRIIWAFIKEKLILPNVDVQLKYFDLGLPHRDKTDDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A KK++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATKKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW +PI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V NF GGGV MGM
Sbjct: 163 GWTQPITIGRHAHGDQYKATDFVVNKSGTFKMVFTPKDGSGVKEWEVFNFP-GGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI+DK YK++F+
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTEFDKL 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD+N EL FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDSNPELIKFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ ++NT +F+D + L L +
Sbjct: 402 CVETVESGTMTKDLAGCIHGLANVKLNEHFVNTTDFLDAIKNTLDKALGK 451
>sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
dbj|BAC40149.1| unnamed protein product [Mus musculus]
gb|AAH60030.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Mus musculus]
dbj|BAE41142.1| unnamed protein product [Mus musculus]
dbj|BAE36505.1| unnamed protein product [Mus musculus]
dbj|BAE26628.1| unnamed protein product [Mus musculus]
gb|EDL07035.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial, isoform CRA_d
[Mus musculus]
Length = 452
Score = 731 bits (1887), Expect = 0.0, Method: Composition-based stats.
Identities = 283/410 (69%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 43 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ ++ K WPLYLSTKNTILK YDGRFKDIFQEI+DK YK+ F+
Sbjct: 222 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
++T+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 402 CVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGK 451
>ref|NP_970434.1| isocitrate dehydrogenase [Bdellovibrio bacteriovorus HD100]
emb|CAE81088.1| isocitrate dehydrogenase (NADP) [Bdellovibrio bacteriovorus HD100]
Length = 409
Score = 730 bits (1886), Expect = 0.0, Method: Composition-based stats.
Identities = 284/410 (69%), Positives = 334/410 (81%), Gaps = 2/410 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
M K VVE+ GDEMTRIIW+ IK++LI PY+++D+ YDLG+E+RDATNDQVT DA
Sbjct: 1 MKKIKVANPVVELDGDEMTRIIWKFIKQQLILPYLDIDIKYYDLGMEHRDATNDQVTVDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVG+KCATITPDE RV+EF LKQMWKSPNGTIRNIL GTVFRE IICKN+PRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEARVKEFNLKQMWKSPNGTIRNILDGTVFREPIICKNVPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V W PI IGRHA+GDQYRATDFV G GK+ +T+ P +G + +T+ V+NF +G GVA+
Sbjct: 121 VPNWTAPICIGRHAFGDQYRATDFVTKGKGKLTVTFQPENGGETITHEVYNF-KGDGVAL 179
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
MYN D+SI FA S F AL+K WPLYLSTKNTILKKYDGRFKDIF+EIY K++K++F+
Sbjct: 180 TMYNTDESITGFARSCFNQALTKKWPLYLSTKNTILKKYDGRFKDIFEEIYQKEFKAKFD 239
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A I YEHRLIDDMVA A+K G F+WACKNYDGDVQSD+VAQG+GSLG+MTSVLV PDG
Sbjct: 240 AAGITYEHRLIDDMVASALKWNGNFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLVTPDG 299
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KT+E+EAAHGTVTRHYR +Q+G+ TSTNPIASIFAWTRGL HR LDNN+EL FA LE
Sbjct: 300 KTMESEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLEHRGNLDNNQELVKFAQTLE 359
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA 410
+V +ET+EAGFMTKDLA CI G V Y+NT F+ KL ENLK L+
Sbjct: 360 KVCVETVEAGFMTKDLAVCIYG-DKVPADKYMNTEPFLAKLDENLKKALS 408
>ref|NP_766599.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Mus musculus]
gb|AAG43538.1|AF212319_1 NADP+-specific isocitrate dehydrogenase [Mus musculus]
Length = 452
Score = 730 bits (1885), Expect = 0.0, Method: Composition-based stats.
Identities = 283/410 (69%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 43 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ ++ K WPLYLSTKNTILK YDGRFKDIFQEI+DK YK+ F+
Sbjct: 222 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDRN 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
++T+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 402 CVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGK 451
>ref|XP_001688948.1| AGAP006660-PA [Anopheles gambiae str. PEST]
ref|XP_001688949.1| AGAP006660-PB [Anopheles gambiae str. PEST]
ref|XP_316694.4| AGAP006660-PC [Anopheles gambiae str. PEST]
gb|EDO63954.1| AGAP006660-PA [Anopheles gambiae str. PEST]
gb|EDO63955.1| AGAP006660-PB [Anopheles gambiae str. PEST]
gb|EAA11493.4| AGAP006660-PC [Anopheles gambiae str. PEST]
Length = 413
Score = 729 bits (1883), Expect = 0.0, Method: Composition-based stats.
Identities = 314/414 (75%), Positives = 369/414 (89%), Gaps = 1/414 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
M+ KI G VV++ GDEMTRIIW+ IKEKLI P+++++LH+YDLGIE+RDATNDQVT D
Sbjct: 1 MASKIKAGPVVDILGDEMTRIIWDSIKEKLILPFLDIELHTYDLGIEHRDATNDQVTIDC 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEA+K++NVG+KCATITPDE RVEEFKLKQMW+SPNGTIRNILGGTVFREAIICKN+PRL
Sbjct: 61 AEAVKRYNVGIKCATITPDEARVEEFKLKQMWRSPNGTIRNILGGTVFREAIICKNVPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V GW KPIIIGRHA+GDQY+ATDFVVP PGK+E+ +TP+DG++ TY+V+ + + GVAM
Sbjct: 121 VPGWEKPIIIGRHAHGDQYKATDFVVPVPGKLEMKFTPADGSEPTTYVVNEY-KSAGVAM 179
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D SI DFAHSSF++AL + +PLYLSTKNTILKKYDGRFKDIFQEIYDK YK QFE
Sbjct: 180 GMYNLDDSICDFAHSSFKVALDRKFPLYLSTKNTILKKYDGRFKDIFQEIYDKDYKKQFE 239
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A IWYEHRLIDDMVA MK+EGGF+WACKNYDGDVQSD+VAQG+GSLG+MTSVLVCPDG
Sbjct: 240 ALGIWYEHRLIDDMVAYCMKAEGGFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLVCPDG 299
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
+TVE+EAAHGTVTRHYR +Q+G+ETSTNPIASIFAWTRGL HRAKLD+N EL FA LE
Sbjct: 300 RTVESEAAHGTVTRHYRQHQQGKETSTNPIASIFAWTRGLLHRAKLDDNAELKRFAETLE 359
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V I+TIE+GFMTKDLA CIKG+ NV+R+DY+ TFEFM+KLGENL+ L Q++L
Sbjct: 360 KVCIDTIESGFMTKDLAICIKGMANVKRTDYMETFEFMNKLGENLQAALTQSRL 413
>emb|CAG02627.1| unnamed protein product [Tetraodon nigroviridis]
Length = 410
Score = 728 bits (1880), Expect = 0.0, Method: Composition-based stats.
Identities = 334/410 (81%), Positives = 373/410 (90%), Gaps = 1/410 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS KI GSVVEMQGDEMTR+IWELIK+KLIFPY++LDLHSYDLGIE RDAT+D+VT +A
Sbjct: 1 MSAKIRAGSVVEMQGDEMTRVIWELIKDKLIFPYLDLDLHSYDLGIEYRDATDDRVTVEA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEA++++NVG+KCATITPDEKRVEEFKLKQMW+SPNGTIRNILGGTVFREAIIC+NIPRL
Sbjct: 61 AEAVQRYNVGIKCATITPDEKRVEEFKLKQMWRSPNGTIRNILGGTVFREAIICRNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V GW KPIIIGRHA+GDQY+ATDFVVP PGKVE+ YTP+ GT Y ++ F+ GGVAM
Sbjct: 121 VPGWTKPIIIGRHAHGDQYKATDFVVPEPGKVEMIYTPTSGT-PTKYTIYEFKGSGGVAM 179
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN DKSI+DFAHSSFQ+ALSKGWPLYLSTKNTILKKYDGRFKDIFQEIY+K+Y S F+
Sbjct: 180 GMYNTDKSIQDFAHSSFQLALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYEKEYISHFK 239
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
+ IWYEHRLIDDMVAQAMKS+GGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 240 DRGIWYEHRLIDDMVAQAMKSDGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 299
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
+TVE+EAAHGTVTRHYR +Q+G+ETSTNPIASIFAWTRGL HRAKLD+N EL F ALE
Sbjct: 300 RTVESEAAHGTVTRHYRQHQEGKETSTNPIASIFAWTRGLLHRAKLDSNAELKSFCEALE 359
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA 410
V IETIE GFMTKDLA CIKGL +V R+DYLNTFEF+DKL ENLK+KL+
Sbjct: 360 AVCIETIEGGFMTKDLAICIKGLAHVTRADYLNTFEFLDKLAENLKVKLS 409
>gb|ACO14046.1| Isocitrate dehydrogenase, mitochondrial precursor [Esox lucius]
Length = 451
Score = 728 bits (1879), Expect = 0.0, Method: Composition-based stats.
Identities = 279/410 (68%), Positives = 325/410 (79%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIWE IKEKLI V+++L YDLG+ RD TNDQVT D+A
Sbjct: 43 RIKVSQPVVEMDGDEMTRIIWEFIKEKLILSNVDVELKYYDLGLPYRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYHVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW +PI IGRHA+GDQYRATDFVV PG ++ ++P+DG++ + V+NF GGG MGM
Sbjct: 163 GWTQPITIGRHAFGDQYRATDFVVNQPGTFKMVFSPTDGSKGQEWGVYNFP-GGGCGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLYLSTKNTILK YDGRFKDIF+EI+ YK +F+
Sbjct: 222 YNTDESISGFAHSCFQYAIGKKWPLYLSTKNTILKAYDGRFKDIFEEIFQANYKPEFDKL 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS+G F+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSDGAFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG TSTNPIASIFAWTRGL HR KLD N +L FA LE V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRGKLDGNPDLIKFALTLERV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL + Y+NT +F+D + +NL L +
Sbjct: 402 CVETVESGVMTKDLAGCIHGLSKCKLNEHYVNTEDFLDAIKKNLDKALGK 451
>gb|ABE98244.1| mitochondrial isocitrate dehydrogenase 2-like [Oreochromis
mossambicus]
Length = 452
Score = 728 bits (1879), Expect = 0.0, Method: Composition-based stats.
Identities = 278/410 (67%), Positives = 325/410 (79%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIWE IKEKLI V+++L +DLG+ RD T+DQVT D+A
Sbjct: 44 RIKVANPVVEMDGDEMTRIIWEFIKEKLILTNVDVELKYFDLGLPYRDQTDDQVTIDSAL 103
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A KK++V VKCATITPDE RVEEF LK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 104 ATKKYSVAVKCATITPDEARVEEFGLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 163
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW +PI IGRHA+GDQYRATDFVV PGK +I ++P+DG+ + V +F GG MGM
Sbjct: 164 GWTQPITIGRHAFGDQYRATDFVVDQPGKFKIVFSPADGSTSKEWEVFDFPAGGC-GMGM 222
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQ+I++K YK +F+
Sbjct: 223 YNTDESITGFAHSCFQYAIGKKWPLYMSTKNTILKAYDGRFKDIFQDIFEKNYKPEFDKL 282
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS G F+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 283 KIWYEHRLIDDMVAQVLKSSGAFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 342
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N +L FA LE+V
Sbjct: 343 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNPDLIKFAQTLEQV 402
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ T+E+G MTKDLA CI GL NV+ Y+NT +F+D + NL L +
Sbjct: 403 CVATVESGTMTKDLAGCIHGLSNVKLNEHYVNTTDFLDAIKTNLDKALGK 452
>emb|CAM77136.1| Isocitrate/isopropylmalate dehydrogenase [Magnetospirillum
gryphiswaldense MSR-1]
Length = 405
Score = 727 bits (1878), Expect = 0.0, Method: Composition-based stats.
Identities = 278/412 (67%), Positives = 329/412 (79%), Gaps = 7/412 (1%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
M+K +VE+ GDEMTRIIW+ IK+KLI PY+++DL YDLG+E RD TNDQVT DA
Sbjct: 1 MNKIKVANPIVELDGDEMTRIIWKFIKDKLILPYLDVDLKYYDLGVEYRDETNDQVTIDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIK++ VGVKCATITPDE RV+EF LK+MWKSPNGTIRNIL GTVFRE IIC+N+PRL
Sbjct: 61 AEAIKQYGVGVKCATITPDEARVKEFNLKKMWKSPNGTIRNILDGTVFREPIICQNVPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V GW KPI+IGRHA+GDQYRATDF VPGPG + + + DG Q + + V NF GVAM
Sbjct: 121 VPGWTKPIVIGRHAFGDQYRATDFKVPGPGILTMKFVGEDG-QVIEHEVFNFPSS-GVAM 178
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI FA + L+K WP+YLSTKNTILK YDGRFKDIFQE+Y+K++K++F+
Sbjct: 179 GMYNLDESIRGFARACMNYGLAKKWPVYLSTKNTILKAYDGRFKDIFQEVYEKEFKAEFD 238
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
+ YEHRLIDDMVA A+K G F+WACKNYDGDVQSD+VAQG+GSLG+MTSVL+ PDG
Sbjct: 239 KYGMTYEHRLIDDMVASALKWSGEFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLSPDG 298
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYR +QKG+ETSTNPIASIFAWTRGL +RA+ DN E+A FA ALE
Sbjct: 299 KTVEAEAAHGTVTRHYREHQKGKETSTNPIASIFAWTRGLLYRAQFDNTPEVAKFATALE 358
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQA 412
EV +ET+EAGFMTKDLA I +L T +F+DKL ENLK K+ A
Sbjct: 359 EVCVETVEAGFMTKDLAILIG-----PDQPWLTTTQFLDKLDENLKKKMGVA 405
>ref|NP_001014183.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Rattus
norvegicus]
sp|P56574|IDHP_RAT Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAH76398.1| Similar to NADP+-specific isocitrate dehydrogenase [Rattus
norvegicus]
gb|EDM08608.1| similar to NADP+-specific isocitrate dehydrogenase, isoform CRA_b
[Rattus norvegicus]
Length = 452
Score = 727 bits (1878), Expect = 0.0, Method: Composition-based stats.
Identities = 282/410 (68%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 43 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGMFKLVFTPKDGSGAKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ ++ K WPLYLSTKNTI+K YDGRFKDIFQEI+DK YK+ F+
Sbjct: 222 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTIMKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
++T+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 402 CVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGK 451
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|XP_001107627.1| PREDICTED: isocitrate dehydrogenase 1 (... 760 0.0
ref|NP_001009276.1| cytosolic NADP-isocitrate dehydrogenase... 758 0.0
ref|NP_851355.2| isocitrate dehydrogenase 1 (NADP+), solubl... 758 0.0
emb|CAG38738.1| IDH1 [Homo sapiens] 758 0.0
sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytopl... 757 0.0
ref|NP_005887.2| isocitrate dehydrogenase 1 (NADP+), solubl... 757 0.0
ref|NP_113698.1| isocitrate dehydrogenase 1 (NADP+), solubl... 756 0.0
ref|XP_850187.1| PREDICTED: similar to Isocitrate dehydroge... 756 0.0
sp|Q5R9C5|IDHC_PONPY Isocitrate dehydrogenase [NADP] cytopl... 756 0.0
sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytopl... 756 0.0
ref|XP_001141655.1| PREDICTED: isocitrate dehydrogenase 1 (... 756 0.0
sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytopl... 755 0.0
gb|AAH93020.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 755 0.0
emb|CAD97653.1| hypothetical protein [Homo sapiens] >gi|117... 754 0.0
emb|CAB66637.1| hypothetical protein [Homo sapiens] >gi|117... 753 0.0
sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytopl... 753 0.0
ref|XP_421965.2| PREDICTED: similar to cytosolic NADP-depen... 753 0.0
ref|XP_001505172.1| PREDICTED: similar to Isocitrate dehydr... 753 0.0
gb|ABU41004.1| isocitrate dehydrogenase 1 [Anser anser] 752 0.0
ref|NP_034627.3| isocitrate dehydrogenase 1 (NADP+), solubl... 752 0.0
emb|CAH89719.1| hypothetical protein [Pongo abelii] 752 0.0
emb|CAH91635.1| hypothetical protein [Pongo abelii] 751 0.0
dbj|BAC39792.1| unnamed protein product [Mus musculus] 751 0.0
gb|AAH88986.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 751 0.0
dbj|BAE39644.1| unnamed protein product [Mus musculus] 751 0.0
gb|AAD02918.1| NADP-dependent isocitrate dehydrogenase [Hom... 750 0.0
ref|NP_001088022.1| hypothetical protein LOC494713 [Xenopus... 750 0.0
emb|CAG38553.1| IDH1 [Homo sapiens] 749 0.0
ref|XP_536192.2| PREDICTED: similar to isocitrate dehydroge... 748 0.0
ref|NP_001026770.1| hypothetical protein LOC431056 [Gallus ... 746 0.0
ref|NP_786984.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 746 0.0
ref|XP_001365492.1| PREDICTED: similar to cytosolic NADP-de... 746 0.0
sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitoc... 746 0.0
ref|XP_001511049.1| PREDICTED: similar to cytosolic NADP-de... 745 0.0
pdb|2CMJ|A Chain A, Crystal Structure Of Mouse Cytosolic Is... 745 0.0
ref|XP_860821.1| PREDICTED: similar to Isocitrate dehydroge... 744 0.0
sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitoc... 744 0.0
ref|XP_001369305.1| PREDICTED: hypothetical protein [Monode... 743 0.0
ref|NP_766599.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 742 0.0
ref|XP_860853.1| PREDICTED: similar to Isocitrate dehydroge... 741 0.0
ref|NP_001014183.1| isocitrate dehydrogenase 2 (NADP+), mit... 741 0.0
gb|ABE98244.1| mitochondrial isocitrate dehydrogenase 2-lik... 740 0.0
ref|XP_510589.2| PREDICTED: isocitrate dehydrogenase 2 (NAD... 740 0.0
ref|NP_955858.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 740 0.0
ref|XP_001095686.1| PREDICTED: isocitrate dehydrogenase 2 (... 739 0.0
gb|ACO14046.1| Isocitrate dehydrogenase, mitochondrial prec... 739 0.0
ref|NP_002159.2| isocitrate dehydrogenase 2 (NADP+), mitoch... 738 0.0
pdb|1LWD|A Chain A, Crystal Structure Of Nadp-Dependent Iso... 738 0.0
emb|CAA49208.1| isocitrate dehydrogenase (NADP+) [Homo sapi... 738 0.0
sp|P33198|IDHP_PIG Isocitrate dehydrogenase [NADP], mitocho... 737 0.0
dbj|BAD96636.1| isocitrate dehydrogenase 2 (NADP+), mitocho... 736 0.0
ref|XP_001168316.1| PREDICTED: isocitrate dehydrogenase 2 (... 736 0.0
gb|EAX02083.1| isocitrate dehydrogenase 2 (NADP+), mitochon... 735 0.0
ref|XP_001778805.1| predicted protein [Physcomitrella paten... 735 0.0
ref|NP_539708.1| isocitrate dehydrogenase [Brucella meliten... 735 0.0
ref|NP_698203.1| isocitrate dehydrogenase [Brucella suis 13... 734 0.0
emb|CAA53300.1| isocitrate dehydrogenase (NADP+) [Solanum t... 734 0.0
dbj|BAC77065.1| NADP-specific isocitrate dehydrogenase [Lup... 733 0.0
emb|CAM77136.1| Isocitrate/isopropylmalate dehydrogenase [M... 733 0.0
ref|NP_970434.1| isocitrate dehydrogenase [Bdellovibrio bac... 733 0.0
ref|XP_001633903.1| predicted protein [Nematostella vectens... 733 0.0
gb|AAB39248.1| NADP-isocitrate dehydrogenase [Eucalyptus gl... 732 0.0
ref|XP_001168291.1| PREDICTED: isocitrate dehydrogenase 2 (... 732 0.0
gb|AAC64182.1| NADP-dependent isocitrate dehydrogenase [Gly... 732 0.0
emb|CAG02362.1| unnamed protein product [Tetraodon nigrovir... 731 0.0
emb|CAQ15240.1| isocitrate dehydrogenase 1 (NADP+), soluble... 730 0.0
ref|NP_001056381.1| Os05g0573200 [Oryza sativa (japonica cu... 730 0.0
ref|NP_958907.1| isocitrate dehydrogenase 1 (NADP+), solubl... 730 0.0
emb|CAG13105.1| unnamed protein product [Tetraodon nigrovir... 730 0.0
ref|NP_001080321.1| hypothetical protein LOC380013 [Xenopus... 730 0.0
sp|P50218|IDHC_TOBAC Isocitrate dehydrogenase [NADP] (Oxalo... 729 0.0
sp|P50217|IDHC_SOLTU Isocitrate dehydrogenase [NADP] (Oxalo... 728 0.0
ref|ZP_00056387.1| COG0538: Isocitrate dehydrogenases [Magn... 728 0.0
ref|NP_001043749.1| Os01g0654500 [Oryza sativa (japonica cu... 728 0.0
ref|YP_419971.1| isocitrate dehydrogenase [Magnetospirillum... 728 0.0
gb|EEJ98364.1| isocitrate dehydrogenase (NADP) [Thermomonos... 728 0.0
ref|XP_001688948.1| AGAP006660-PA [Anopheles gambiae str. P... 727 0.0
sp|Q40345|IDHP_MEDSA Isocitrate dehydrogenase [NADP], chlor... 727 0.0
ref|XP_001841910.1| isocitrate dehydrogenase cytoplasmic [C... 727 0.0
ref|NP_001004799.1| MGC69505 protein [Xenopus tropicalis] >... 726 0.0
ref|XP_001778590.1| predicted protein [Physcomitrella paten... 726 0.0
ref|XP_001168261.1| PREDICTED: isocitrate dehydrogenase 2 (... 726 0.0
gb|AAA33978.1| NADPH-specific isocitrate dehydrogenase 726 0.0
ref|YP_001370537.1| isocitrate dehydrogenase, NADP-dependen... 726 0.0
ref|YP_290624.1| isocitrate dehydrogenase [Thermobifida fus... 725 0.0
emb|CAG02627.1| unnamed protein product [Tetraodon nigrovir... 725 0.0
gb|ABK24873.1| unknown [Picea sitchensis] 725 0.0
pir||S33612 isocitrate dehydrogenase (NADP) (EC 1.1.1.42) -... 724 0.0
dbj|BAA34112.1| NADP specific isocitrate dehydrogenase [Dau... 724 0.0
dbj|BAA34113.1| NADP specific isocitrate dehydrogenase [Dau... 724 0.0
gb|ABA18651.1| cytosolic NADP+-isocitrate dehydrogenase [Po... 724 0.0
ref|ZP_02188085.1| Isocitrate dehydrogenase [alpha proteoba... 724 0.0
ref|ZP_01885694.1| isocitrate dehydrogenase [Pedobacter sp.... 723 0.0
ref|YP_677841.1| isocitrate dehydrogenase [Cytophaga hutchi... 723 0.0
ref|YP_002826161.1| NADP isocitrate dehydrogenase [Rhizobiu... 723 0.0
gb|AAL11503.1|AF367443_1 NADP-dependent isocitrate dehydrog... 723 0.0
gb|AAD51361.1|AF176669_1 NADP-isocitrate dehydrogenase [Cit... 723 0.0
dbj|BAC77063.1| NADP-specific isocitrate dehydrogenase [Lup... 723 0.0
emb|CAA65503.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 722 0.0
ref|NP_385898.1| isocitrate dehydrogenase [Sinorhizobium me... 722 0.0
dbj|BAE48792.1| NADP-isocitrate dehydrogenase [Codonopsis l... 722 0.0
emb|CAA73139.1| isocitrate dehydrogenase (NADP+) [Apium gra... 721 0.0
emb|CAA65504.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 721 0.0
ref|NP_101923.1| isocitrate dehydrogenase [Mesorhizobium lo... 721 0.0
gb|EDT29808.1| isocitrate dehydrogenase, NADP-dependent [Ol... 721 0.0
ref|NP_196963.2| isocitrate dehydrogenase, putative / NADP+... 721 0.0
gb|AAC52473.1| isocitrate dehydrogenase 721 0.0
gb|AAF73472.1|AF268076_1 NADP-dependent isocitrate dehydrog... 720 0.0
ref|ZP_03891012.1| isocitrate dehydrogenase (NADP) [Geoderm... 720 0.0
prf||2211361A isocitrate dehydrogenase 720 0.0
sp|Q06197|IDHC_SOYBN Isocitrate dehydrogenase [NADP] (Oxalo... 720 0.0
ref|YP_002761841.1| NADP-dependent isocitrate dehydrogenase... 720 0.0
ref|XP_001650675.1| nadp-specific isocitrate dehydrogenase ... 720 0.0
ref|YP_001327198.1| isocitrate dehydrogenase [Sinorhizobium... 720 0.0
ref|XP_001698704.1| isocitrate dehydrogenase, NADP-dependen... 719 0.0
dbj|BAC77064.1| NADP-specific isocitrate dehydrogenase [Lup... 719 0.0
emb|CAD24779.1| isocitrate dehydrogenase [Cucumis sativus] 719 0.0
gb|AAT06312.1| isocitrate dehydrogenase [Rhizobium legumino... 719 0.0
ref|YP_768215.1| isocitrate dehydrogenase [Rhizobium legumi... 719 0.0
ref|YP_706173.1| isocitrate dehydrogenase [Rhodococcus sp. ... 719 0.0
gb|AAR05796.1| NADP+-isocitrate dehydrogenase [Pinus pinaster] 719 0.0
ref|XP_970446.1| PREDICTED: similar to isocitrate dehydroge... 719 0.0
ref|YP_673828.1| isocitrate dehydrogenase [Mesorhizobium sp... 718 0.0
ref|ZP_02124492.1| Isocitrate dehydrogenase (NADP(+)) [Meth... 718 0.0
ref|ZP_02858718.1| isocitrate dehydrogenase, NADP-dependent... 718 0.0
ref|ZP_02295934.1| isocitrate dehydrogenase, NADP-dependent... 718 0.0
ref|YP_425448.1| isocitrate dehydrogenase [Rhodospirillum r... 718 0.0
ref|ZP_02166681.1| isocitrate dehydrogenase [Hoeflea photot... 718 0.0
gb|EAY99113.1| hypothetical protein OsI_020346 [Oryza sativ... 717 0.0
ref|NP_421325.1| isocitrate dehydrogenase [Caulobacter cres... 717 0.0
ref|NP_354851.2| isocitrate dehydrogenase [Agrobacterium tu... 717 0.0
ref|XP_968850.1| PREDICTED: similar to CG7176-PC, isoform C... 717 0.0
emb|CAN72808.1| hypothetical protein [Vitis vinifera] >gi|1... 717 0.0
ref|NP_175836.1| ICDH; isocitrate dehydrogenase (NADP+) [Ar... 716 0.0
ref|ZP_03869030.1| isocitrate dehydrogenase (NADP) [Jonesia... 716 0.0
ref|XP_001903959.1| unnamed protein product [Podospora anse... 715 0.0
ref|YP_001685152.1| isocitrate dehydrogenase, NADP-dependen... 715 0.0
ref|XP_001176537.1| PREDICTED: similar to Isocitrate dehydr... 715 0.0
gb|ACO14957.1| Isocitrate dehydrogenase cytoplasmic [Caligu... 715 0.0
ref|YP_001524781.1| NADP-dependent isocitrate dehydrogenase... 714 0.0
gb|AAS49171.1| NADP-dependent isocitrate dehydrogenase [Pis... 714 0.0
ref|YP_001413846.1| isocitrate dehydrogenase, NADP-dependen... 714 0.0
ref|YP_001609735.1| NADP-dependent isocitrate dehydrogenase... 714 0.0
ref|YP_001769504.1| isocitrate dehydrogenase, NADP-dependen... 714 0.0
gb|AAV33246.1| isocitrate dehydrogenase [Toxoplasma gondii] 714 0.0
ref|YP_872148.1| isocitrate dehydrogenase [Acidothermus cel... 714 0.0
ref|YP_117132.1| isocitrate dehydrogenase [Nocardia farcini... 714 0.0
ref|XP_001226620.1| conserved hypothetical protein [Chaetom... 714 0.0
ref|XP_001240510.1| isocitrate dehydrogenase NADP, mitochon... 713 0.0
ref|XP_955850.1| hypothetical protein NCU03857 [Neurospora ... 713 0.0
ref|YP_002783489.1| isocitrate dehydrogenase [Rhodococcus o... 713 0.0
ref|ZP_01228834.1| NADP dependent isocitrate dehydrogenase ... 713 0.0
ref|NP_176768.1| isocitrate dehydrogenase, putative / NADP+... 712 0.0
emb|CAB87626.1| isocitrate dehydrogenase-like protein [Arab... 712 0.0
ref|YP_002765452.1| NADP-dependent isocitrate dehydrogenase... 711 0.0
ref|NP_001040134.1| isocitrate dehydrogenase [Bombyx mori] ... 711 0.0
gb|AAM13090.1| similar to NADP-specific isocitrate dehydrog... 711 0.0
ref|YP_001419447.1| isocitrate dehydrogenase, NADP-dependen... 710 0.0
ref|XP_312860.4| AGAP003168-PA [Anopheles gambiae str. PEST... 710 0.0
ref|YP_001296741.1| isocitrate dehydrogenase [Flavobacteriu... 710 0.0
emb|CAA63220.1| isocitrate dehydrogenase (NAD+) [Solanum tu... 709 0.0
emb|CAD24782.1| isocitrate dehydrogenase [Arabidopsis thali... 709 0.0
gb|AAM65674.1| isocitrate dehydrogenase, putative [Arabidop... 709 0.0
ref|XP_001608101.1| PREDICTED: similar to isocitrate dehydr... 709 0.0
ref|NP_001042583.1| Os01g0248400 [Oryza sativa (japonica cu... 708 0.0
ref|XP_821599.1| isocitrate dehydrogenase, putative [Trypan... 708 0.0
ref|YP_001623415.1| isocitrate dehydrogenase (NADP) [Reniba... 708 0.0
gb|AAT44354.1| isocitrate dehydrogenase [Crassostrea gigas] 708 0.0
ref|ZP_03896321.1| isocitrate dehydrogenase (NADP) [Dyadoba... 708 0.0
ref|NP_772387.1| isocitrate dehydrogenase [Bradyrhizobium j... 708 0.0
emb|CAO64975.1| unnamed protein product [Vitis vinifera] 708 0.0
ref|ZP_00952302.1| isocitrate dehydrogenase [Oceanicaulis a... 708 0.0
ref|YP_032403.1| isocitrate dehydrogenase [Bartonella quint... 707 0.0
ref|ZP_01862723.1| isocitrate dehydrogenase [Erythrobacter ... 707 0.0
ref|NP_001053269.1| Os04g0508200 [Oryza sativa (japonica cu... 707 0.0
ref|YP_001538953.1| isocitrate dehydrogenase, NADP-dependen... 707 0.0
ref|XP_754749.1| isocitrate dehydrogenase Idp1 [Aspergillus... 707 0.0
gb|EDP52872.1| isocitrate dehydrogenase Idp1, putative [Asp... 707 0.0
ref|XP_001426548.1| hypothetical protein GSPATT00029781001 ... 707 0.0
ref|XP_001457045.1| hypothetical protein GSPATT00022820001 ... 707 0.0
ref|YP_001108727.1| isocitrate dehydrogenase [Saccharopolys... 707 0.0
ref|YP_001832264.1| isocitrate dehydrogenase, NADP-dependen... 707 0.0
ref|ZP_03819206.1| isocitrate dehydrogenase (NADP) [Actinos... 706 0.0
ref|YP_001160602.1| isocitrate dehydrogenase [Salinispora t... 706 0.0
ref|ZP_01546031.1| isocitrate dehydrogenase [Stappia aggreg... 706 0.0
ref|YP_033790.1| isocitrate dehydrogenase [Bartonella hense... 706 0.0
gb|ABI52605.1| isocitrate dehydrogenase [Gryllus firmus] 706 0.0
ref|XP_623673.2| PREDICTED: similar to Isocitrate dehydroge... 706 0.0
emb|CAE04728.1| OSJNBa0043L24.16 [Oryza sativa (japonica cu... 705 0.0
ref|ZP_02955422.1| isocitrate dehydrogenase, NADP-dependent... 705 0.0
gb|EAY58582.1| isocitrate dehydrogenase [NADP] icd1 [Mycoba... 705 0.0
ref|XP_001593497.1| hypothetical protein SS1G_04924 [Sclero... 705 0.0
ref|NP_217856.1| isocitrate dehydrogenase [Mycobacterium tu... 705 0.0
ref|ZP_01440188.1| Isocitrate/isopropylmalate dehydrogenase... 704 0.0
ref|ZP_01303522.1| isocitrate dehydrogenase, NADP-dependent... 704 0.0
ref|YP_979491.1| isocitrate dehydrogenase [Mycobacterium bo... 704 0.0
ref|YP_001233708.1| isocitrate dehydrogenase [Acidiphilium ... 704 0.0
ref|YP_682929.1| isocitrate dehydrogenase [Roseobacter deni... 703 0.0
emb|CAH67563.1| OSIGBa0101P20.6 [Oryza sativa (indica culti... 703 0.0
ref|NP_001093090.1| NADPH-specific isocitrate dehydrogenase... 703 0.0
ref|NP_949171.1| isocitrate dehydrogenase [Rhodopseudomonas... 703 0.0
ref|ZP_03813993.1| isocitrate dehydrogenase (NADP) [Beutenb... 703 0.0
ref|YP_001849499.1| isocitrate dehydrogenase [NADP] Icd1 [M... 703 0.0
ref|YP_989041.1| isocitrate dehydrogenase [Bartonella bacil... 703 0.0
ref|YP_001204807.1| isocitrate dehydrogenase [Bradyrhizobiu... 703 0.0
ref|YP_496560.1| isocitrate dehydrogenase [Novosphingobium ... 702 0.0
ref|YP_001709366.1| isocitrate dehydrogenase [Clavibacter m... 702 0.0
ref|YP_001223282.1| isocitrate dehydrogenase [Clavibacter m... 702 0.0
ref|YP_001833636.1| isocitrate dehydrogenase, NADP-dependen... 702 0.0
gb|AAK76730.1| mitochondrial NADP-dependent isocitrate dehy... 702 0.0
ref|XP_780121.1| PREDICTED: similar to cytosolic NADP-depen... 701 0.0
ref|YP_001758392.1| isocitrate dehydrogenase, NADP-dependen... 701 0.0
ref|YP_487337.1| isocitrate dehydrogenase [Rhodopseudomonas... 701 0.0
ref|YP_617009.1| isocitrate dehydrogenase [Sphingopyxis ala... 701 0.0
ref|ZP_03922528.1| isocitrate dehydrogenase [Mobiluncus cur... 701 0.0
ref|ZP_02302766.1| isocitrate dehydrogenase, NADP-dependent... 701 0.0
ref|XP_451683.1| unnamed protein product [Kluyveromyces lac... 700 0.0
ref|YP_756242.1| isocitrate dehydrogenase [Maricaulis maris... 700 0.0
ref|XP_001670101.1| Hypothetical protein CBG21657 [Caenorha... 700 0.0
ref|YP_909639.1| isocitrate dehydrogenase [Bifidobacterium ... 700 0.0
ref|YP_001241304.1| isocitrate dehydrogenase [Bradyrhizobiu... 699 0.0
ref|XP_001845030.1| isocitrate dehydrogenase [Culex pipiens... 699 0.0
ref|XP_390523.1| hypothetical protein FG10347.1 [Gibberella... 699 0.0
ref|ZP_01046178.1| isocitrate dehydrogenase NADP-dependent ... 699 0.0
ref|YP_001363715.1| isocitrate dehydrogenase, NADP-dependen... 699 0.0
sp|P79089|IDHP_ASPNG Isocitrate dehydrogenase [NADP], mitoc... 698 0.0
ref|YP_062774.1| isocitrate dehydrogenase [Leifsonia xyli s... 698 0.0
ref|YP_317907.1| isocitrate dehydrogenase [Nitrobacter wino... 698 0.0
ref|YP_458429.1| isocitrate dehydrogenase [Erythrobacter li... 698 0.0
ref|ZP_01040029.1| isocitrate dehydrogenase [Erythrobacter ... 698 0.0
gb|ABD77209.1| isocitrate dehydrogenase 1 [Rattus norvegicus] 698 0.0
gb|ABK25438.1| unknown [Picea sitchensis] 697 0.0
ref|XP_001384028.1| Isocitrate dehydrogenase [NADP], mitoch... 697 0.0
ref|XP_001462393.1| hypothetical protein GSPATT00027349001 ... 697 0.0
ref|XP_001020930.2| dehydrogenase, isocitrate/isopropylmala... 697 0.0
sp|P50215|IDH_SPHYA Isocitrate dehydrogenase [NADP] (Oxalos... 697 0.0
ref|YP_568874.1| isocitrate dehydrogenase [Rhodopseudomonas... 697 0.0
ref|ZP_00206729.1| COG0538: Isocitrate dehydrogenases [Bifi... 697 0.0
ref|XP_001454244.1| hypothetical protein GSPATT00020509001 ... 696 0.0
ref|XP_367343.2| hypothetical protein MGG_07268 [Magnaporth... 696 0.0
ref|XP_504978.1| hypothetical protein [Yarrowia lipolytica]... 696 0.0
ref|YP_576902.1| isocitrate dehydrogenase [Nitrobacter hamb... 696 0.0
ref|ZP_00954676.1| isocitrate dehydrogenase [Sulfitobacter ... 696 0.0
ref|YP_780531.1| isocitrate dehydrogenase [Rhodopseudomonas... 696 0.0
ref|ZP_00964081.1| isocitrate dehydrogenase [Sulfitobacter ... 696 0.0
gb|ABO93633.1| isocitrate dehydrogenase 2 [Toxoplasma gondii] 696 0.0
ref|YP_001169228.1| isocitrate dehydrogenase [Rhodobacter s... 696 0.0
ref|NP_696658.1| isocitrate dehydrogenase [Bifidobacterium ... 695 0.0
ref|YP_001168561.1| isocitrate dehydrogenase [Rhodobacter s... 695 0.0
ref|XP_001676039.1| Hypothetical protein CBG17397 [Caenorha... 695 0.0
ref|ZP_03977360.1| isocitrate dehydrogenase (NADP(+)) [Bifi... 695 0.0
ref|YP_531457.1| isocitrate dehydrogenase [Rhodopseudomonas... 695 0.0
ref|NP_501665.1| F59B8.2 [Caenorhabditis elegans] >gi|38778... 694 0.0
ref|ZP_03993927.1| isocitrate dehydrogenase [Mobiluncus mul... 694 0.0
gb|AAK76731.1| peroxisomal NADP-dependent isocitrate dehydr... 694 0.0
ref|XP_001400371.1| precursor of mitochondrial isocitrate d... 694 0.0
ref|YP_001043974.1| isocitrate dehydrogenase [Rhodobacter s... 693 0.0
ref|YP_001042101.1| isocitrate dehydrogenase [Rhodobacter s... 693 0.0
gb|ABD77208.1| isocitrate dehydrogenase 1 [Mus musculus] 692 0.0
ref|YP_353519.1| isocitrate dehydrogenase [Rhodobacter spha... 692 0.0
ref|YP_001260963.1| isocitrate dehydrogenase [Sphingomonas ... 692 0.0
ref|XP_001837820.1| hypothetical protein CC1G_11465 [Coprin... 692 0.0
ref|NP_509875.1| C34F6.8 [Caenorhabditis elegans] >gi|38747... 692 0.0
ref|NP_962389.1| isocitrate dehydrogenase [Mycobacterium av... 692 0.0
ref|YP_759895.1| isocitrate dehydrogenase [Hyphomonas neptu... 692 0.0
ref|XP_001528456.1| isocitrate dehydrogenase, mitochondrial... 692 0.0
ref|YP_351602.1| isocitrate dehydrogenase [Rhodobacter spha... 691 0.0
gb|AAI53922.1| Idh1 protein [Danio rerio] 691 0.0
ref|XP_710919.1| NADP-specific isocitrate dehydrogenase [Ca... 691 0.0
ref|XP_001484278.1| isocitrate dehydrogenase, mitochondrial... 691 0.0
ref|YP_001601185.1| Isocitrate dehydrogenase [Gluconacetoba... 690 0.0
ref|YP_883449.1| isocitrate dehydrogenase [Mycobacterium av... 690 0.0
ref|XP_459772.1| hypothetical protein DEHA0E11286g [Debaryo... 689 0.0
gb|ABL97438.1| isocitrate dehydrogenase [uncultured marine ... 689 0.0
gb|ABF20272.1| mitochondrial isocitrate dehydrogenase [Leis... 689 0.0
gb|ABD77216.1| isocitrate dehydrogenase 1 [Aotus trivirgatus] 689 0.0
gb|ABD77215.1| isocitrate dehydrogenase 1 [Homo sapiens] 689 0.0
ref|ZP_01157336.1| isocitrate dehydrogenase [Oceanicola gra... 688 0.0
ref|ZP_02963068.1| isocitrate dehydrogenase [Bifidobacteriu... 688 0.0
ref|ZP_01448513.1| isocitrate dehydrogenase [alpha proteoba... 688 0.0
ref|ZP_01018081.1| isocitrate dehydrogenase [Parvularcula b... 688 0.0
gb|ABF20244.1| mitochondrial isocitrate dehydrogenase [Leis... 688 0.0
ref|ZP_02981592.1| isocitrate dehydrogenase, NADP-dependent... 688 0.0
ref|ZP_00960755.1| Isocitrate dehydrogenase [Roseovarius nu... 688 0.0
ref|ZP_01130474.1| isocitrate dehydrogenase [marine actinob... 688 0.0
ref|XP_001463680.1| isocitrate dehydrogenase [NADP], mitoch... 688 0.0
ref|XP_001507484.1| PREDICTED: similar to isocitrate dehydr... 687 0.0
ref|NP_729367.1| Isocitrate dehydrogenase CG7176-PD, isofor... 687 0.0
ref|XP_001263574.1| isocitrate dehydrogenase Idp1, putative... 687 0.0
ref|XP_660603.1| IDHP_ASPNG ISOCITRATE DEHYDROGENASE [NADP]... 686 0.0
ref|XP_001878769.1| predicted protein [Laccaria bicolor S23... 686 0.0
ref|NP_926944.1| isocitrate dehydrogenase [Gloeobacter viol... 686 0.0
ref|NP_729366.1| Isocitrate dehydrogenase CG7176-PB, isofor... 686 0.0
ref|XP_001270886.1| isocitrate dehydrogenase Idp1, putative... 686 0.0
ref|XP_001818331.1| hypothetical protein [Aspergillus oryza... 686 0.0
ref|XP_001681361.1| isocitrate dehydrogenase [NADP], mitoch... 685 0.0
ref|XP_001614236.1| isocitrate dehydrogenase [NADP], mitoch... 685 0.0
ref|NP_652044.1| Isocitrate dehydrogenase CG7176-PC, isofor... 685 0.0
ref|XP_713421.1| cytosolic NADP-specific isocitrate dehydro... 685 0.0
ref|XP_001634205.1| predicted protein [Nematostella vectens... 685 0.0
Sequences not found previously or not previously below threshold:
>ref|XP_001107627.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 1
[Macaca mulatta]
ref|XP_001107810.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 2
[Macaca mulatta]
ref|XP_001107875.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 3
[Macaca mulatta]
ref|XP_001107934.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 4
[Macaca mulatta]
ref|XP_001107992.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 5
[Macaca mulatta]
Length = 414
Score = 760 bits (1962), Expect = 0.0, Method: Composition-based stats.
Identities = 410/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVE+QGDEMTRIIWELIKEKLIFPYVELDL SYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVELQGDEMTRIIWELIKEKLIFPYVELDLQSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>ref|NP_001009276.1| cytosolic NADP-isocitrate dehydrogenase [Ovis aries]
sp|Q6XUZ5|IDHC_SHEEP Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAP41947.1| cytosolic NADP-isocitrate dehydrogenase [Ovis aries]
Length = 414
Score = 758 bits (1959), Expect = 0.0, Method: Composition-based stats.
Identities = 394/414 (95%), Positives = 401/414 (96%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS KI GGSVVEMQGDEMTRIIWELIKEKLIFPYV+LDLHSYDL IENRDATNDQVTKDA
Sbjct: 1 MSHKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVDLDLHSYDLSIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEI YTPSDG+ K YLVHNF E GGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEICYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GM+NQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMFNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL++KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAKL 414
>ref|NP_851355.2| isocitrate dehydrogenase 1 (NADP+), soluble [Bos taurus]
gb|AAI03369.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Bos taurus]
Length = 414
Score = 758 bits (1958), Expect = 0.0, Method: Composition-based stats.
Identities = 396/414 (95%), Positives = 404/414 (97%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEI+YTPSDG+ K YLVHNF E GGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKS+FE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL++KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAKL 414
>emb|CAG38738.1| IDH1 [Homo sapiens]
Length = 414
Score = 758 bits (1957), Expect = 0.0, Method: Composition-based stats.
Identities = 413/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVE+TYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02924.1| cytosolic NADP-dependent isocitrate dehydrogenase [Microtus
mexicanus]
Length = 414
Score = 757 bits (1955), Expect = 0.0, Method: Composition-based stats.
Identities = 397/414 (95%), Positives = 407/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEIT+TP DG+QKVTYLVH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITFTPKDGSQKVTYLVHSFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAW+RGLAHRA+LDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>ref|NP_005887.2| isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens]
sp|O75874|IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
pdb|1T09|A Chain A, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex Nadp
pdb|1T09|B Chain B, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex Nadp
pdb|1T0L|A Chain A, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|B Chain B, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|C Chain C, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|D Chain D, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
gb|AAD29284.1|AF113917_1 NADP+-dependent isocitrate dehydrogenase [Homo sapiens]
gb|AAH12846.1| IDH1 protein [Homo sapiens]
emb|CAG46496.1| IDH1 [Homo sapiens]
gb|AAX93221.1| unknown [Homo sapiens]
gb|EAW70439.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|EAW70441.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|EAW70442.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|ABM82361.1| isocitrate dehydrogenase 1 (NADP+), soluble [synthetic construct]
gb|ABW03396.1| isocitrate dehydrogenase 1 (NADP+), soluble [synthetic construct]
Length = 414
Score = 757 bits (1955), Expect = 0.0, Method: Composition-based stats.
Identities = 414/414 (100%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>ref|NP_113698.1| isocitrate dehydrogenase 1 (NADP+), soluble [Rattus norvegicus]
sp|P41562|IDHC_RAT Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAA59356.1| cytosolic NADP-dependent isocitrate dehydrogenase
gb|EDL98861.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98863.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98864.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98865.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
Length = 414
Score = 756 bits (1954), Expect = 0.0, Method: Composition-based stats.
Identities = 399/414 (96%), Positives = 408/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DG+QKVTYLVH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKS+FE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSKFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>ref|XP_850187.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 2 [Canis familiaris]
ref|XP_536047.2| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 1 [Canis familiaris]
Length = 414
Score = 756 bits (1954), Expect = 0.0, Method: Composition-based stats.
Identities = 401/414 (96%), Positives = 408/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDG++K+TYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL IKLAQAKL
Sbjct: 361 EVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL 414
>sp|Q5R9C5|IDHC_PONPY Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
Length = 414
Score = 756 bits (1953), Expect = 0.0, Method: Composition-based stats.
Identities = 411/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVS+ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02925.1| cytosolic NADP-dependent isocitrate dehydrogenase [Microtus
ochrogaster]
Length = 414
Score = 756 bits (1953), Expect = 0.0, Method: Composition-based stats.
Identities = 398/414 (96%), Positives = 407/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DG+QKVTYLVH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHSFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAW+RGLAHRA+LDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>ref|XP_001141655.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 1
[Pan troglodytes]
ref|XP_001141734.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 2
[Pan troglodytes]
ref|XP_001141810.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 3
[Pan troglodytes]
ref|XP_001141879.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 4
[Pan troglodytes]
ref|XP_001141947.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 5
[Pan troglodytes]
ref|XP_001142041.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 6
[Pan troglodytes]
ref|XP_001142113.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 7
[Pan troglodytes]
ref|XP_001142197.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 8
[Pan troglodytes]
Length = 414
Score = 756 bits (1952), Expect = 0.0, Method: Composition-based stats.
Identities = 412/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKRYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD34457.1|AF136009_1 cytosolic NADP+-dependent isocitrate dehydrogenase [Bos taurus]
Length = 414
Score = 755 bits (1951), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 403/414 (97%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEI+YTPSDG+ K YLVHNF E GGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKS+FE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQET TNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETLTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL++KLAQAKL
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAKL 414
>gb|AAH93020.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens]
Length = 414
Score = 755 bits (1951), Expect = 0.0, Method: Composition-based stats.
Identities = 413/414 (99%), Positives = 414/414 (100%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAE+AHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAESAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAD97653.1| hypothetical protein [Homo sapiens]
emb|CAL38069.1| hypothetical protein [synthetic construct]
emb|CAL37462.1| hypothetical protein [synthetic construct]
Length = 414
Score = 754 bits (1948), Expect = 0.0, Method: Composition-based stats.
Identities = 412/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHN E GGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>emb|CAB66637.1| hypothetical protein [Homo sapiens]
emb|CAL37490.1| hypothetical protein [synthetic construct]
Length = 414
Score = 753 bits (1945), Expect = 0.0, Method: Composition-based stats.
Identities = 412/414 (99%), Positives = 413/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWV+PIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02919.1| NADP-dependent isocitrate dehydrogenase [Mus musculus]
Length = 414
Score = 753 bits (1944), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 405/414 (97%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ I YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQNICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>ref|XP_421965.2| PREDICTED: similar to cytosolic NADP-dependent isocitrate
dehydrogenase [Gallus gallus]
Length = 415
Score = 753 bits (1944), Expect = 0.0, Method: Composition-based stats.
Identities = 369/410 (90%), Positives = 392/410 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTR+IWELIKEKLIFPYV+LDLHSYDLGIE+RDATND+VT +A
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIEHRDATNDKVTVEA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK++VG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYHVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPI+IGRHAYGDQYRATDFVVPGPGKVE+TYTP DG + VTYLVHNFE GGVAM
Sbjct: 121 VSGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEMTYTPGDGGKPVTYLVHNFESCGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI+DFAHSSFQMALSKGWPLY+STKNTILK+YDGRFKDIFQEIYD++YKSQFE
Sbjct: 181 GMYNLDQSIKDFAHSSFQMALSKGWPLYMSTKNTILKRYDGRFKDIFQEIYDREYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQA+KSEGGF+WACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAWTRGLAHRAKLDNN L FA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWTRGLAHRAKLDNNTSLKTFATALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA 410
EV IETIE+GFMTKDLAACIKGLPNV RSDYLNTFEFMDKL NLK KLA
Sbjct: 361 EVCIETIESGFMTKDLAACIKGLPNVTRSDYLNTFEFMDKLAANLKGKLA 410
>ref|XP_001505172.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Cytosolic NADP-isocitrate dehydrogenase)
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) [Equus caballus]
Length = 414
Score = 753 bits (1944), Expect = 0.0, Method: Composition-based stats.
Identities = 400/414 (96%), Positives = 408/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFP+VELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPHVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPG+VEITYTPSDG+QK TYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGRVEITYTPSDGSQKRTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQY+SQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYRSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELGFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 DVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>gb|ABU41004.1| isocitrate dehydrogenase 1 [Anser anser]
Length = 415
Score = 752 bits (1943), Expect = 0.0, Method: Composition-based stats.
Identities = 369/410 (90%), Positives = 393/410 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI GGSVVEMQGDEMTR+IWELIKEKLIFPYV+LDLHSYDLGIE+RDATND+VT +A
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIEHRDATNDKVTVEA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK++VG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYHVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPI+IGRHAYGDQYRATDFVVPGPGKVE+TYTP DG + VTYLVHNFE GGVAM
Sbjct: 121 VSGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEMTYTPGDGGKPVTYLVHNFESCGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GM+N D+SI+DFAHSSFQMALSKGWPLY+STKNTILK+YDGRFKDIFQEIYD++YKSQFE
Sbjct: 181 GMFNLDQSIKDFAHSSFQMALSKGWPLYMSTKNTILKRYDGRFKDIFQEIYDREYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQA+KSEGGF+WACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAWTRGLAHRAKLDNN L FA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWTRGLAHRAKLDNNTSLKTFAAALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA 410
EV IETIE+GFMTKDLAACIKGLPNV RSDYLNTFEFMDKL ENLK KLA
Sbjct: 361 EVCIETIESGFMTKDLAACIKGLPNVTRSDYLNTFEFMDKLAENLKGKLA 410
>ref|NP_034627.3| isocitrate dehydrogenase 1 (NADP+), soluble [Mus musculus]
ref|NP_001104790.1| isocitrate dehydrogenase 1 (NADP+), soluble [Mus musculus]
dbj|BAE36075.1| unnamed protein product [Mus musculus]
dbj|BAE30207.1| unnamed protein product [Mus musculus]
dbj|BAE39299.1| unnamed protein product [Mus musculus]
dbj|BAE34873.1| unnamed protein product [Mus musculus]
dbj|BAE28720.1| unnamed protein product [Mus musculus]
gb|EDL00223.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Mus
musculus]
gb|EDL00225.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Mus
musculus]
Length = 414
Score = 752 bits (1943), Expect = 0.0, Method: Composition-based stats.
Identities = 396/414 (95%), Positives = 406/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>emb|CAH89719.1| hypothetical protein [Pongo abelii]
Length = 414
Score = 752 bits (1942), Expect = 0.0, Method: Composition-based stats.
Identities = 409/414 (98%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWE IKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWEQIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVS+ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA AKL
Sbjct: 361 EVSVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLALAKL 414
>emb|CAH91635.1| hypothetical protein [Pongo abelii]
Length = 414
Score = 751 bits (1941), Expect = 0.0, Method: Composition-based stats.
Identities = 409/414 (98%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKD FQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDTFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPI SIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIVSIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVS+ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>dbj|BAC39792.1| unnamed protein product [Mus musculus]
Length = 422
Score = 751 bits (1940), Expect = 0.0, Method: Composition-based stats.
Identities = 394/413 (95%), Positives = 405/413 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQA+
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAQ 413
>gb|AAH88986.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Mus musculus]
Length = 414
Score = 751 bits (1939), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 406/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEA+KK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEALKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>dbj|BAE39644.1| unnamed protein product [Mus musculus]
Length = 414
Score = 751 bits (1939), Expect = 0.0, Method: Composition-based stats.
Identities = 396/414 (95%), Positives = 406/414 (98%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSRKIKGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKI YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
+V IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAKL
Sbjct: 361 DVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAKL 414
>gb|AAD02918.1| NADP-dependent isocitrate dehydrogenase [Homo sapiens]
Length = 414
Score = 750 bits (1938), Expect = 0.0, Method: Composition-based stats.
Identities = 411/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILK YDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKIYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTN IASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNLIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTKDLAACI+GLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKDLAACIRGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>ref|NP_001088022.1| hypothetical protein LOC494713 [Xenopus laevis]
gb|AAH82651.1| LOC494713 protein [Xenopus laevis]
Length = 415
Score = 750 bits (1936), Expect = 0.0, Method: Composition-based stats.
Identities = 363/410 (88%), Positives = 391/410 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKI+GGSVVEMQGDEMTR+IW+LIKEKLI PYVELDLHSYDLG+ENRDAT+DQVT DA
Sbjct: 1 MSKKINGGSVVEMQGDEMTRVIWDLIKEKLILPYVELDLHSYDLGMENRDATDDQVTVDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVG+KCATITPDEKRVEEF LKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEKRVEEFNLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGW+KPIIIGRHAYGDQYRATDFVVPGPGKVEI++TP DG + + Y++HNFE+ GGVA+
Sbjct: 121 VSGWIKPIIIGRHAYGDQYRATDFVVPGPGKVEISFTPKDGGEAIKYVIHNFEDCGGVAL 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI DFAHSSFQMALSK WPLY+STKNTILK+YDGRFKDIFQEIY+K+YKSQFE
Sbjct: 181 GMYNTDQSIRDFAHSSFQMALSKSWPLYMSTKNTILKRYDGRFKDIFQEIYEKEYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 ENKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRM+QKGQETSTNPIASIFAW+RGL HRAKLDNN+EL FA ALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLDHRAKLDNNQELKNFATALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA 410
EV IETIEAGFMTKDLAACIKGLPNVQR DYL+TFEFMDKLGENL++KLA
Sbjct: 361 EVCIETIEAGFMTKDLAACIKGLPNVQRGDYLSTFEFMDKLGENLQLKLA 410
>emb|CAG38553.1| IDH1 [Homo sapiens]
Length = 414
Score = 749 bits (1935), Expect = 0.0, Method: Composition-based stats.
Identities = 411/414 (99%), Positives = 412/414 (99%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MSKKISGGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWV+PIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
Sbjct: 121 VSGWVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EVSIETIEAGFMTK LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
Sbjct: 361 EVSIETIEAGFMTKGLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
>ref|XP_536192.2| PREDICTED: similar to isocitrate dehydrogenase 2 (NADP+),
mitochondrial [Canis familiaris]
Length = 517
Score = 748 bits (1932), Expect = 0.0, Method: Composition-based stats.
Identities = 284/410 (69%), Positives = 331/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 109 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 168
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 169 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 228
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G +I ++P DG+ + V+NF GGGV MGM
Sbjct: 229 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKIIFSPKDGSGAKEWEVYNFP-GGGVGMGM 287
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI++K YK+ F+
Sbjct: 288 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKN 347
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 348 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 407
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 408 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 467
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
++T+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L Q
Sbjct: 468 CVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKNNLDKALGQ 517
>ref|NP_001026770.1| hypothetical protein LOC431056 [Gallus gallus]
emb|CAG31511.1| hypothetical protein [Gallus gallus]
Length = 452
Score = 746 bits (1928), Expect = 0.0, Method: Composition-based stats.
Identities = 282/410 (68%), Positives = 328/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW IKEKLI P V++ L +DLG+ +RD T+DQVT D+A
Sbjct: 43 RIKVANPVVEMDGDEMTRIIWAFIKEKLILPNVDVQLKYFDLGLPHRDKTDDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A KK++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATKKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW +PI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V NF GGGV MGM
Sbjct: 163 GWTQPITIGRHAHGDQYKATDFVVNKSGTFKMVFTPKDGSGVKEWEVFNFP-GGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI+DK YK++F+
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTEFDKL 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD+N EL FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDSNPELIKFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ ++NT +F+D + L L +
Sbjct: 402 CVETVESGTMTKDLAGCIHGLANVKLNEHFVNTTDFLDAIKNTLDKALGK 451
>ref|NP_786984.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Bos taurus]
emb|CAA49207.1| isocitrate dehydrogenase (NADP+) [Bos taurus]
Length = 452
Score = 746 bits (1928), Expect = 0.0, Method: Composition-based stats.
Identities = 283/410 (69%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQ I++K YK++F+
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDKH 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L Q
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGQ 451
>ref|XP_001365492.1| PREDICTED: similar to cytosolic NADP-dependent isocitrate
dehydrogenase [Monodelphis domestica]
Length = 414
Score = 746 bits (1928), Expect = 0.0, Method: Composition-based stats.
Identities = 369/414 (89%), Positives = 397/414 (95%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI+GGSVVEMQGDEMTR+IW+LIK+KLIFPYV LDLHSYDLGIE+RD T+DQVT DA
Sbjct: 1 MSQKINGGSVVEMQGDEMTRVIWDLIKQKLIFPYVNLDLHSYDLGIEHRDETDDQVTIDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
V+GWVKPI+IGRHAYGDQYRATDFVVPGPGKVEI+YTP DG++ VTYL+HNFE+ GGVAM
Sbjct: 121 VNGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEISYTPRDGSKTVTYLIHNFEDCGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI DFAHSSFQMAL+KGWPLY+STKNTILKKYDGRFKDIFQ+IYD YKS+FE
Sbjct: 181 GMYNLDQSIMDFAHSSFQMALTKGWPLYMSTKNTILKKYDGRFKDIFQKIYDTHYKSKFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQA+KSEGGF+WACKNYDGDVQSDS+AQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSIAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLD+NKEL FA LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDDNKELGTFATILE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV IETIE+GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKL ENLK KLAQAKL
Sbjct: 361 EVCIETIESGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLAENLKAKLAQAKL 414
>sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAI02510.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Bos taurus]
Length = 452
Score = 746 bits (1928), Expect = 0.0, Method: Composition-based stats.
Identities = 283/410 (69%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQ I++K YK++F+
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDKH 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L Q
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGQ 451
>ref|XP_001511049.1| PREDICTED: similar to cytosolic NADP-dependent isocitrate
dehydrogenase [Ornithorhynchus anatinus]
Length = 415
Score = 745 bits (1924), Expect = 0.0, Method: Composition-based stats.
Identities = 374/415 (90%), Positives = 396/415 (95%), Gaps = 1/415 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS KI GGSVVEMQGDEMTR+IWELIKEKLIFPYV+LDLHSYDLGIENRDATND+VT +A
Sbjct: 1 MSSKICGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIENRDATNDKVTSEA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVG+KCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVP PGKVE+ YTP DG + VTYLVHNFE GGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPRPGKVEMVYTPQDGGKAVTYLVHNFEAGGGVAM 180
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYN D+SI DFAHSSFQMALSK WPLY+STKNTILK+YDGRFKDIFQEIY+KQY+S+FE
Sbjct: 181 GMYNLDQSIRDFAHSSFQMALSKSWPLYMSTKNTILKRYDGRFKDIFQEIYEKQYRSKFE 240
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
A+KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDG
Sbjct: 241 AKKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRH+RM+QKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+ FA LE
Sbjct: 301 KTVEAEAAHGTVTRHFRMHQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSTFATTLE 360
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLA-QAKL 414
+V +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLA QAKL
Sbjct: 361 DVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLASQAKL 415
>pdb|2CMJ|A Chain A, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase
pdb|2CMJ|B Chain B, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase
pdb|2CMV|A Chain A, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase Complexed With Cadmium And Citrate
pdb|2CMV|B Chain B, Crystal Structure Of Mouse Cytosolic Isocitrate
Dehydrogenase Complexed With Cadmium And Citrate
Length = 410
Score = 745 bits (1924), Expect = 0.0, Method: Composition-based stats.
Identities = 392/410 (95%), Positives = 401/410 (97%)
Query: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
KI GGSVVEMQGDEMTRIIWELIKEKLI PYVELDLHSYDLGIENRDATNDQVTKDAAEA
Sbjct: 1 KIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDAAEA 60
Query: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
IKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 61 IKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 120
Query: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTP DGTQKVTY+VH+FEEGGGVAMGMY
Sbjct: 121 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAMGMY 180
Query: 184 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQK 243
NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDK+YKSQFEAQ
Sbjct: 181 NQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFEAQN 240
Query: 244 IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTV 303
I YEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVL+CPDGKTV
Sbjct: 241 ICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDGKTV 300
Query: 304 EAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVS 363
EAEAAHGTVTRHYRMYQKGQETSTNPIASIFAW+RGLAHRAKLDNN EL+FFA ALE+V
Sbjct: 301 EAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALEDVC 360
Query: 364 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLK KLAQAK
Sbjct: 361 IETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAK 410
>ref|XP_860821.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 4 [Canis familiaris]
Length = 415
Score = 744 bits (1922), Expect = 0.0, Method: Composition-based stats.
Identities = 397/416 (95%), Positives = 406/416 (97%), Gaps = 3/416 (0%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYL--VHNFEEGGGV 178
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDG++K+TYL V +F +GGGV
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYLIQVLSF-KGGGV 179
Query: 179 AMGMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQ 238
AMGMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQ
Sbjct: 180 AMGMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQ 239
Query: 239 FEAQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCP 298
FEAQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCP
Sbjct: 240 FEAQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCP 299
Query: 299 DGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANA 358
DGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA A
Sbjct: 300 DGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKA 359
Query: 359 LEEVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
LEEV +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL IKLAQAKL
Sbjct: 360 LEEVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL 415
>sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
dbj|BAC40149.1| unnamed protein product [Mus musculus]
gb|AAH60030.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Mus musculus]
dbj|BAE41142.1| unnamed protein product [Mus musculus]
dbj|BAE36505.1| unnamed protein product [Mus musculus]
dbj|BAE26628.1| unnamed protein product [Mus musculus]
gb|EDL07035.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial, isoform CRA_d
[Mus musculus]
Length = 452
Score = 744 bits (1921), Expect = 0.0, Method: Composition-based stats.
Identities = 283/410 (69%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 43 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ ++ K WPLYLSTKNTILK YDGRFKDIFQEI+DK YK+ F+
Sbjct: 222 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
++T+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 402 CVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGK 451
>ref|XP_001369305.1| PREDICTED: hypothetical protein [Monodelphis domestica]
Length = 455
Score = 743 bits (1919), Expect = 0.0, Method: Composition-based stats.
Identities = 282/410 (68%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ +RD T+DQVT D+A
Sbjct: 46 RIKVDKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPHRDQTDDQVTIDSAL 105
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 106 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 165
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW +PI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 166 GWTRPITIGRHAHGDQYKATDFVVDKAGTFKMVFTPKDGSGAKEWEVYNFP-AGGVGMGM 224
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI+DK YK+ F+
Sbjct: 225 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 284
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 285 KIWYEHRLIDDMVAQVLKSNGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 344
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 345 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIKFAQTLEKV 404
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
++T+E+G MTKDLA CI GL NV+ YLNT +F+D + NL L Q
Sbjct: 405 CVQTVESGAMTKDLAGCIHGLSNVKLNEHYLNTGDFLDTIKNNLDKALGQ 454
>ref|NP_766599.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Mus musculus]
gb|AAG43538.1|AF212319_1 NADP+-specific isocitrate dehydrogenase [Mus musculus]
Length = 452
Score = 742 bits (1917), Expect = 0.0, Method: Composition-based stats.
Identities = 283/410 (69%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 43 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ ++ K WPLYLSTKNTILK YDGRFKDIFQEI+DK YK+ F+
Sbjct: 222 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDRN 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
++T+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 402 CVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGK 451
>ref|XP_860853.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 5 [Canis familiaris]
Length = 408
Score = 741 bits (1915), Expect = 0.0, Method: Composition-based stats.
Identities = 395/414 (95%), Positives = 402/414 (97%), Gaps = 6/414 (1%)
Query: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
MS+KI GGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
AEAIKK+NVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDG++K+TYL GGGVAM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYL------GGGVAM 174
Query: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
GMYNQDKSIEDFAHSSFQMALSK WPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
Sbjct: 175 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 234
Query: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
AQ IWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
Sbjct: 235 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 294
Query: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKEL+FFA ALE
Sbjct: 295 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 354
Query: 361 EVSIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL 414
EV +ETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENL IKLAQAKL
Sbjct: 355 EVCVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAKL 408
>ref|NP_001014183.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Rattus
norvegicus]
sp|P56574|IDHP_RAT Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAH76398.1| Similar to NADP+-specific isocitrate dehydrogenase [Rattus
norvegicus]
gb|EDM08608.1| similar to NADP+-specific isocitrate dehydrogenase, isoform CRA_b
[Rattus norvegicus]
Length = 452
Score = 741 bits (1914), Expect = 0.0, Method: Composition-based stats.
Identities = 282/410 (68%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 43 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGMFKLVFTPKDGSGAKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ ++ K WPLYLSTKNTI+K YDGRFKDIFQEI+DK YK+ F+
Sbjct: 222 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTIMKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
++T+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 402 CVQTVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGK 451
>gb|ABE98244.1| mitochondrial isocitrate dehydrogenase 2-like [Oreochromis
mossambicus]
Length = 452
Score = 740 bits (1912), Expect = 0.0, Method: Composition-based stats.
Identities = 278/410 (67%), Positives = 325/410 (79%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIWE IKEKLI V+++L +DLG+ RD T+DQVT D+A
Sbjct: 44 RIKVANPVVEMDGDEMTRIIWEFIKEKLILTNVDVELKYFDLGLPYRDQTDDQVTIDSAL 103
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A KK++V VKCATITPDE RVEEF LK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 104 ATKKYSVAVKCATITPDEARVEEFGLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 163
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW +PI IGRHA+GDQYRATDFVV PGK +I ++P+DG+ + V +F GG MGM
Sbjct: 164 GWTQPITIGRHAFGDQYRATDFVVDQPGKFKIVFSPADGSTSKEWEVFDFP-AGGCGMGM 222
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQ+I++K YK +F+
Sbjct: 223 YNTDESITGFAHSCFQYAIGKKWPLYMSTKNTILKAYDGRFKDIFQDIFEKNYKPEFDKL 282
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS G F+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 283 KIWYEHRLIDDMVAQVLKSSGAFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 342
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N +L FA LE+V
Sbjct: 343 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNPDLIKFAQTLEQV 402
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ T+E+G MTKDLA CI GL NV+ Y+NT +F+D + NL L +
Sbjct: 403 CVATVESGTMTKDLAGCIHGLSNVKLNEHYVNTTDFLDAIKTNLDKALGK 452
>ref|XP_510589.2| PREDICTED: isocitrate dehydrogenase 2 (NADP+), mitochondrial
isoform 4 [Pan troglodytes]
Length = 452
Score = 740 bits (1912), Expect = 0.0, Method: Composition-based stats.
Identities = 282/410 (68%), Positives = 329/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD T+DQVT D+A
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI+DK YK+ F+
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>ref|NP_955858.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Danio rerio]
gb|AAH48041.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Danio rerio]
gb|AAH63967.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Danio rerio]
Length = 449
Score = 740 bits (1912), Expect = 0.0, Method: Composition-based stats.
Identities = 280/410 (68%), Positives = 326/410 (79%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIWE IKEKLI V +DL YDLG+ RD T+DQVT D+A
Sbjct: 41 RIQVAQPVVEMDGDEMTRIIWEFIKEKLILTNVNVDLKYYDLGLPYRDQTDDQVTIDSAI 100
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A KK+NV VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 101 ATKKYNVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 160
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW + I IGRHA+GDQY+ATDFVV PGK ++ +TP+DG++ + V++F GGG MGM
Sbjct: 161 GWTQAITIGRHAFGDQYKATDFVVNQPGKFKMVFTPADGSKNKEWEVYDFP-GGGCGMGM 219
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQ+I++K YK +F+
Sbjct: 220 YNTDESITGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQDIFEKNYKPEFDKL 279
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS G F+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 280 KIWYEHRLIDDMVAQVLKSSGAFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 339
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N +L F+ LE V
Sbjct: 340 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNPDLIKFSQTLERV 399
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL N + Y+NT +F+D + NL L +
Sbjct: 400 CVETVESGVMTKDLAGCIHGLANCKLNEHYVNTTDFLDAIKTNLDKALGK 449
>ref|XP_001095686.1| PREDICTED: isocitrate dehydrogenase 2 (NADP+), mitochondrial
[Macaca mulatta]
sp|Q4R502|IDHP_MACFA Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
dbj|BAE01823.1| unnamed protein product [Macaca fascicularis]
Length = 452
Score = 739 bits (1910), Expect = 0.0, Method: Composition-based stats.
Identities = 282/410 (68%), Positives = 329/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD T+DQVT D+A
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI+DK YK+ F+
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>gb|ACO14046.1| Isocitrate dehydrogenase, mitochondrial precursor [Esox lucius]
Length = 451
Score = 739 bits (1909), Expect = 0.0, Method: Composition-based stats.
Identities = 279/410 (68%), Positives = 325/410 (79%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIWE IKEKLI V+++L YDLG+ RD TNDQVT D+A
Sbjct: 43 RIKVSQPVVEMDGDEMTRIIWEFIKEKLILSNVDVELKYYDLGLPYRDQTNDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYHVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW +PI IGRHA+GDQYRATDFVV PG ++ ++P+DG++ + V+NF GGG MGM
Sbjct: 163 GWTQPITIGRHAFGDQYRATDFVVNQPGTFKMVFSPTDGSKGQEWGVYNFP-GGGCGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLYLSTKNTILK YDGRFKDIF+EI+ YK +F+
Sbjct: 222 YNTDESISGFAHSCFQYAIGKKWPLYLSTKNTILKAYDGRFKDIFEEIFQANYKPEFDKL 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS+G F+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSDGAFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG TSTNPIASIFAWTRGL HR KLD N +L FA LE V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRGKLDGNPDLIKFALTLERV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL + Y+NT +F+D + +NL L +
Sbjct: 402 CVETVESGVMTKDLAGCIHGLSKCKLNEHYVNTEDFLDAIKKNLDKALGK 451
>ref|NP_002159.2| isocitrate dehydrogenase 2 (NADP+), mitochondrial precursor [Homo
sapiens]
sp|P48735|IDHP_HUMAN Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAH09244.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Homo sapiens]
gb|AAH71828.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Homo sapiens]
gb|EAX02082.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial, isoform CRA_a
[Homo sapiens]
gb|ABM83743.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [synthetic
construct]
gb|ABM87062.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [synthetic
construct]
Length = 452
Score = 738 bits (1907), Expect = 0.0, Method: Composition-based stats.
Identities = 282/410 (68%), Positives = 329/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD T+DQVT D+A
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI+DK YK+ F+
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>pdb|1LWD|A Chain A, Crystal Structure Of Nadp-Dependent Isocitrate
Dehydrogenase From Porcine Heart Mitochondria
pdb|1LWD|B Chain B, Crystal Structure Of Nadp-Dependent Isocitrate
Dehydrogenase From Porcine Heart Mitochondria
Length = 413
Score = 738 bits (1905), Expect = 0.0, Method: Composition-based stats.
Identities = 284/410 (69%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 4 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 63
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 64 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 123
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G +I +TP DG+ + V+NF GGV MGM
Sbjct: 124 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKIVFTPKDGSSAKQWEVYNFP-AGGVGMGM 182
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI++K YK+ F+
Sbjct: 183 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKY 242
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 243 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 302
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 303 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 362
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 363 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGR 412
>emb|CAA49208.1| isocitrate dehydrogenase (NADP+) [Homo sapiens]
Length = 452
Score = 738 bits (1905), Expect = 0.0, Method: Composition-based stats.
Identities = 282/410 (68%), Positives = 329/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD T+DQVT D+A
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFV G ++ +TP DG+ + V+NF GGV MGM
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGM 221
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI+DK YK+ F+
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKV 401
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTMDFLDTIKSNLDRALGR 451
>sp|P33198|IDHP_PIG Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAA31089.1| NADPH-specific isocitrate dehydrogenase
Length = 421
Score = 737 bits (1904), Expect = 0.0, Method: Composition-based stats.
Identities = 284/410 (69%), Positives = 330/410 (80%), Gaps = 2/410 (0%)
Query: 3 KKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAE 62
+ VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD TNDQVT D+A
Sbjct: 12 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 71
Query: 63 AIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVS 122
A +K++V VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV
Sbjct: 72 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 131
Query: 123 GWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGM 182
GW KPI IGRHA+GDQY+ATDFVV G +I +TP DG+ + V+NF GGV MGM
Sbjct: 132 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKIVFTPKDGSSAKQWEVYNFP-AGGVGMGM 190
Query: 183 YNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQ 242
YN D+SI FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI++K YK+ F+
Sbjct: 191 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKY 250
Query: 243 KIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKT 302
KIWYEHRLIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT
Sbjct: 251 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 310
Query: 303 VEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEV 362
+EAEAAHGTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V
Sbjct: 311 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 370
Query: 363 SIETIEAGFMTKDLAACIKGLPNVQ-RSDYLNTFEFMDKLGENLKIKLAQ 411
+ET+E+G MTKDLA CI GL NV+ +LNT +F+D + NL L +
Sbjct: 371 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGR 420
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.314 0.171 0.529
Lambda K H
0.267 0.0522 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,611,711,653
Number of Sequences: 6899187
Number of extensions: 429303175
Number of successful extensions: 911398
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 6625
Number of HSP's successfully gapped in prelim test: 1913
Number of HSP's that attempted gapping in prelim test: 875375
Number of HSP's gapped (non-prelim): 9905
length of query: 414
length of database: 2,350,152,223
effective HSP length: 137
effective length of query: 277
effective length of database: 1,404,963,604
effective search space: 389174918308
effective search space used: 389174918308
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.1 bits)
S2: 81 (35.5 bits)