BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= ENSG00000158125__[Homo_sapiens]
         (1333 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           6,899,187 sequences; 2,350,152,223 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|AAA75287.1|  xanthine dehydrogenase                           2743   0.0  
ref|NP_000370.2|  xanthine dehydrogenase [Homo sapiens] >gi|...  2729   0.0  
pdb|2E1Q|A  Chain A, Crystal Structure Of Human Xanthine Oxi...  2726   0.0  
ref|XP_525729.2|  PREDICTED: xanthine dehydrogenase [Pan tro...  2717   0.0  
ref|NP_001116410.1|  xanthine dehydrogenase/oxidase [Oryctol...  2559   0.0  
ref|XP_001501608.1|  PREDICTED: similar to xanthine dehydrog...  2531   0.0  
ref|XP_540143.2|  PREDICTED: similar to Xanthine dehydrogena...  2511   0.0  
ref|NP_001009217.1|  xanthine dehydrogenase [Felis catus] >g...  2511   0.0  
ref|XP_862631.1|  PREDICTED: similar to Xanthine dehydrogena...  2510   0.0  
ref|XP_862539.1|  PREDICTED: similar to Xanthine dehydrogena...  2509   0.0  
ref|XP_862684.1|  PREDICTED: similar to Xanthine dehydrogena...  2508   0.0  
gb|EDM02851.1|  rCG61833 [Rattus norvegicus]                     2497   0.0  
ref|XP_862658.1|  PREDICTED: similar to Xanthine dehydrogena...  2496   0.0  
ref|NP_058850.1|  xanthine dehydrogenase [Rattus norvegicus]...  2491   0.0  
ref|XP_862565.1|  PREDICTED: similar to Xanthine dehydrogena...  2491   0.0  
gb|ABL96618.1|  xanthine oxidoreductase [Capra hircus]           2491   0.0  
ref|XP_001501696.1|  PREDICTED: similar to xanthine dehydrog...  2488   0.0  
pdb|2E3T|A  Chain A, Crystal Structure Of Rat Xanthine Oxido...  2482   0.0  
pdb|1WYG|A  Chain A, Crystal Structure Of A Rat Xanthine Deh...  2479   0.0  
gb|AAI41184.1|  Xanthine dehydrogenase [Mus musculus]            2478   0.0  
ref|NP_035853.2|  xanthine dehydrogenase [Mus musculus]          2477   0.0  
sp|Q00519|XDH_MOUSE  Xanthine dehydrogenase/oxidase [Include...  2475   0.0  
emb|CAA44705.1|  xanthine dehydrogenase [Mus musculus]           2475   0.0  
gb|EDL38417.1|  xanthine dehydrogenase, isoform CRA_a [Mus m...  2475   0.0  
dbj|BAE26022.1|  unnamed protein product [Mus musculus]          2472   0.0  
sp|P80457|XDH_BOVIN  Xanthine dehydrogenase/oxidase [Include...  2472   0.0  
ref|NP_776397.1|  xanthine dehydrogenase [Bos taurus] >gi|11...  2469   0.0  
pdb|1N5X|A  Chain A, Xanthine Dehydrogenase From Bovine Milk...  2467   0.0  
gb|AAD17938.1|  xanthine:oxygen oxidoreductase [Tragelaphus ...  2454   0.0  
gb|AAD17937.1|  xanthine:oxygen oxidoreductase [Syncerus caf...  2449   0.0  
emb|CAA67117.1|  xanthine dehydrogenase [Bos taurus]             2446   0.0  
ref|XP_862593.1|  PREDICTED: similar to Xanthine dehydrogena...  2442   0.0  
ref|XP_862613.1|  PREDICTED: similar to Xanthine dehydrogena...  2435   0.0  
ref|XP_001380730.1|  PREDICTED: similar to xanthine dehydrog...  2228   0.0  
ref|NP_990458.1|  xanthine dehydrogenase [Gallus gallus] >gi...  2042   0.0  
ref|XP_001509432.1|  PREDICTED: similar to xanthine oxidored...  1971   0.0  
ref|XP_001515925.1|  PREDICTED: similar to xanthine dehydrog...  1624   0.0  
ref|XP_001606854.1|  PREDICTED: similar to aldehyde oxidase ...  1476   0.0  
pdb|1FIQ|C  Chain C, Crystal Structure Of Xanthine Oxidase F...  1474   0.0  
ref|XP_001662131.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1471   0.0  
ref|XP_001846124.1|  xanthine dehydrogenase [Culex pipiens q...  1464   0.0  
dbj|BAA21640.1|  xanthine dehydrogenase [Bombyx mori]            1458   0.0  
emb|CAP08999.1|  xanthine dehydrogenase [Lutzomyia longipalpis]  1457   0.0  
ref|XP_001606866.1|  PREDICTED: similar to xanthine dehydrog...  1450   0.0  
ref|XP_001119950.1|  PREDICTED: similar to rosy CG7642-PA [A...  1444   0.0  
ref|XP_968229.1|  PREDICTED: similar to CG7642-PA [Tribolium...  1442   0.0  
ref|NP_001037325.1|  xanthine dehydrogenase [Bombyx mori] >g...  1437   0.0  
gb|EDL38419.1|  xanthine dehydrogenase, isoform CRA_c [Mus m...  1422   0.0  
sp|P08793|XDH_CALVI  Xanthine dehydrogenase (XD)                 1416   0.0  
ref|XP_001358503.1|  GA20500-PA [Drosophila pseudoobscura] >...  1412   0.0  
sp|P22811|XDH_DROPS  Xanthine dehydrogenase (XD) (Protein ro...  1412   0.0  
ref|NP_524337.1|  rosy CG7642-PA [Drosophila melanogaster] >...  1408   0.0  
gb|AAA29022.1|  xanthine dehydrogenase (Xdh)                     1408   0.0  
emb|CAA68409.1|  xanthine dehydrogenase [Drosophila melanoga...  1406   0.0  
sp|P91711|XDH_DROSU  Xanthine dehydrogenase (XD) (Protein ro...  1406   0.0  
ref|XP_317568.3|  AGAP007918-PA [Anopheles gambiae str. PEST...  1403   0.0  
gb|AAA27880.1|  xanthine dehydrogenase (AA at 2538)              1400   0.0  
emb|CAA30281.1|  xanthine dehydrogenase [Calliphora vicina]      1398   0.0  
ref|NP_001033781.1|  aldehyde oxidase 1 [Gallus gallus] >gi|...  1395   0.0  
gb|AAG47345.1|  xanthine dehydrogenase [Ceratitis capitata]      1393   0.0  
ref|XP_782082.2|  PREDICTED: similar to xanthine dehydrogena...  1392   0.0  
ref|XP_001193570.1|  PREDICTED: similar to xanthine dehydrog...  1392   0.0  
ref|XP_001648863.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1389   0.0  
gb|AAQ17529.1|  xanthine dehydrogenase [Drosophila erecta]       1388   0.0  
gb|AAQ17533.1|  xanthine dehydrogenase [Drosophila lutescens]    1388   0.0  
ref|XP_001370277.1|  PREDICTED: similar to aldehyde oxidase ...  1387   0.0  
gb|AAQ17526.1|  xanthine dehydrogenase [Drosophila simulans]     1387   0.0  
gb|AAQ17531.1|  xanthine dehydrogenase [Drosophila eugracilis]   1386   0.0  
gb|AAK59699.1|  xanthine dehydrogenase [Poecilia reticulata]     1386   0.0  
ref|NP_001041597.1|  aldehyde oxidase 3 [Canis lupus familia...  1385   0.0  
gb|AAQ17530.1|  xanthine dehydrogenase [Drosophila orena]        1385   0.0  
gb|AAQ17527.1|  xanthine dehydrogenase [Drosophila teissieri]    1383   0.0  
gb|AAQ17528.1|  xanthine dehydrogenase [Drosophila yakuba]       1378   0.0  
gb|AAQ17532.1|  xanthine dehydrogenase [Drosophila mimetica]     1378   0.0  
ref|NP_001008419.1|  aldehyde oxidase 3-like 1 [Mus musculus...  1369   0.0  
emb|CAK04754.2|  novel protein similar to vertebrate aldehyd...  1367   0.0  
ref|XP_610199.3|  PREDICTED: similar to aldehyde oxidase 3 [...  1367   0.0  
ref|XP_699030.2|  PREDICTED: hypothetical protein [Danio rerio]  1364   0.0  
ref|NP_001034690.1|  hypothetical protein LOC424072 [Gallus ...  1356   0.0  
ref|XP_001379598.1|  PREDICTED: hypothetical protein [Monode...  1356   0.0  
gb|AAI05266.1|  Aldehyde oxidase 1 [Bos taurus]                  1354   0.0  
ref|NP_788841.1|  aldehyde oxidase 1 [Bos taurus] >gi|170318...  1352   0.0  
ref|NP_001008522.1|  aldehyde oxidase 3-like 1 [Rattus norve...  1350   0.0  
ref|XP_001509402.1|  PREDICTED: similar to xanthine dehydrog...  1349   0.0  
ref|XP_001089327.1|  PREDICTED: similar to aldehyde oxidase ...  1346   0.0  
ref|XP_001379630.1|  PREDICTED: similar to aldehyde oxidase ...  1346   0.0  
ref|XP_001089912.1|  PREDICTED: similar to aldehyde oxidase ...  1344   0.0  
ref|NP_001008527.1|  aldehyde oxidase 3 [Rattus norvegicus] ...  1343   0.0  
emb|CAH91253.1|  hypothetical protein [Pongo abelii]             1338   0.0  
ref|NP_001150.3|  aldehyde oxidase 1 [Homo sapiens] >gi|1351...  1337   0.0  
gb|AAH26132.1|  Aldehyde oxidase 1 [Mus musculus]                1337   0.0  
ref|NP_033806.2|  aldehyde oxidase 1 [Mus musculus] >gi|1486...  1335   0.0  
dbj|BAA36834.1|  retinal oxidase/aldehyde oxidase [Mus muscu...  1333   0.0  
sp|Q5FB27|ADO_MACFA  Aldehyde oxidase >gi|58737159|dbj|BAD89...  1333   0.0  
ref|XP_001500761.1|  PREDICTED: hypothetical protein [Equus ...  1333   0.0  
gb|AAD31763.1|AF121945_1  aldehyde oxidase [Mus musculus]        1330   0.0  
ref|NP_001037333.1|  xanthine dehydrogenase [Bombyx mori] >g...  1329   0.0  
gb|EAW70208.1|  aldehyde oxidase 1, isoform CRA_a [Homo sapi...  1329   0.0  
dbj|BAB47183.1|  xanthine dehydrogenase [Bombyx mori]            1329   0.0  
gb|EDL99010.1|  aldehyde oxidase 1 [Rattus norvegicus]           1328   0.0  
ref|XP_001500709.1|  PREDICTED: hypothetical protein [Equus ...  1327   0.0  
sp|O54754|ADO_MOUSE  Aldehyde oxidase (Retinal oxidase) >gi|...  1324   0.0  
sp|Q9Z0U5|ADO_RAT  Aldehyde oxidase >gi|4324710|gb|AAD16999....  1324   0.0  
emb|CAK04749.1|  novel protein similar to vertebrate xanthin...  1318   0.0  
ref|XP_001379605.1|  PREDICTED: similar to aldehyde oxidase ...  1317   0.0  
ref|NP_062236.2|  aldehyde oxidase 1 [Rattus norvegicus] >gi...  1315   0.0  
gb|AAL38126.1|  aldehyde oxidase structural homolog 2 [Mus m...  1313   0.0  
ref|NP_001038214.1|  aldehyde oxidase 2 [Canis lupus familia...  1310   0.0  
ref|NP_076106.2|  aldehyde oxidase 3 [Mus musculus] >gi|1486...  1310   0.0  
gb|AAI38877.1|  Aldehyde oxidase 3 [Mus musculus]                1309   0.0  
ref|NP_076120.2|  aldehyde oxidase 4 [Mus musculus] >gi|7415...  1309   0.0  
gb|AAL36596.1|AF322178_1  AOH1 [Mus musculus]                    1308   0.0  
gb|AAI17977.1|  Aox4 protein [Mus musculus]                      1308   0.0  
sp|Q06278|ADO_HUMAN  Aldehyde oxidase >gi|438656|gb|AAA96650...  1306   0.0  
gb|AAB83966.1|  aldehyde oxidase [Homo sapiens]                  1305   0.0  
ref|NP_001075459.1|  retinal oxidase [Oryctolagus cuniculus]...  1304   0.0  
ref|NP_001008523.1|  aldehyde oxidase 4 [Rattus norvegicus] ...  1303   0.0  
ref|XP_001503642.1|  PREDICTED: similar to aldehyde oxidase ...  1300   0.0  
gb|AAF98385.1|AF233581_1  aldehyde oxidase structural homolo...  1298   0.0  
gb|AAD51028.2|AF172276_1  aldehyde oxidase homolog-1 [Mus mu...  1296   0.0  
gb|AAQ24538.1|  aldehyde oxidase 1 [Mus musculus]                1291   0.0  
gb|AAO14865.1|  xanthine dehydrogenase [Anopheles gambiae]       1289   0.0  
gb|AAQ24537.1|  aldehyde oxidase 1 [Mus musculus]                1283   0.0  
ref|XP_635420.1|  xanthine dehydrogenase [Dictyostelium disc...  1280   0.0  
ref|XP_001089798.1|  PREDICTED: similar to aldehyde oxidase ...  1272   0.0  
ref|XP_596585.3|  PREDICTED: similar to aldehyde oxidase 2 [...  1258   0.0  
ref|NP_001086061.1|  MGC81880 protein [Xenopus laevis] >gi|4...  1222   0.0  
ref|XP_688983.2|  PREDICTED: similar to xanthine dehydrogena...  1215   0.0  
ref|XP_001247724.1|  hypothetical protein CIMG_01495 [Coccid...  1205   0.0  
ref|XP_001669778.1|  Hypothetical protein CBG21624 [Caenorha...  1203   0.0  
gb|EDP50488.1|  xanthine dehydrogenase HxA, putative [Asperg...  1197   0.0  
ref|XP_001401908.1|  hypothetical protein An04g05440 [Asperg...  1197   0.0  
ref|XP_751707.1|  xanthine dehydrogenase HxA [Aspergillus fu...  1194   0.0  
gb|EDU48956.1|  xanthine dehydrogenase/oxidase [Pyrenophora ...  1193   0.0  
ref|XP_001266923.1|  xanthine dehydrogenase HxA, putative [N...  1191   0.0  
ref|NP_502747.1|  F55B11.1 [Caenorhabditis elegans] >gi|3877...  1191   0.0  
ref|NP_195215.2|  ATXDH1 (XANTHINE DEHYDROGENASE 1); xanthin...  1189   0.0  
emb|CAD37030.1|  probable xanthine dehydrogenase [Neurospora...  1188   0.0  
emb|CAB45450.1|  xanthine dehydrogenase-like protein [Arabid...  1187   0.0  
ref|XP_956459.2|  xanthine dehydrogenase [Neurospora crassa ...  1185   0.0  
ref|NP_001050420.1|  Os03g0429800 [Oryza sativa (japonica cu...  1185   0.0  
emb|CAO21923.1|  unnamed protein product [Vitis vinifera]        1185   0.0  
ref|XP_001225732.1|  hypothetical protein CHGG_08076 [Chaeto...  1185   0.0  
ref|XP_001820196.1|  hypothetical protein [Aspergillus oryza...  1183   0.0  
ref|XP_001213137.1|  xanthine dehydrogenase [Aspergillus ter...  1182   0.0  
ref|XP_001271985.1|  xanthine dehydrogenase HxA, putative [A...  1180   0.0  
ref|XP_663217.1|  XDH_EMENI Xanthine dehydrogenase (Purine h...  1178   0.0  
emb|CAA58034.1|  xanthine dehydrogenase [Emericella nidulans]    1178   0.0  
ref|XP_381737.1|  hypothetical protein FG01561.1 [Gibberella...  1166   0.0  
gb|EAZ27415.1|  hypothetical protein OsJ_010898 [Oryza sativ...  1160   0.0  
ref|XP_001760766.1|  predicted protein [Physcomitrella paten...  1160   0.0  
ref|XP_001909427.1|  unnamed protein product [Podospora anse...  1160   0.0  
gb|AAR99079.1|  xanthine dehydrogenase 2 [Arabidopsis thaliana]  1155   0.0  
ref|NP_195216.2|  xanthine dehydrogenase [Arabidopsis thaliana]  1155   0.0  
gb|ACO65070.1|  predicted protein [Micromonas sp. RCC299]        1146   0.0  
emb|CAB45451.1|  xanthine dehydrogenase [Arabidopsis thalian...  1143   0.0  
gb|ABF96752.1|  Aldehyde oxidase and xanthine dehydrogenase,...  1135   0.0  
gb|EDL00071.1|  aldehyde oxidase 3-like 1 [Mus musculus]         1134   0.0  
gb|EEH45510.1|  xanthine dehydrogenase [Paracoccidioides bra...  1133   0.0  
ref|XP_001544612.1|  xanthine dehydrogenase [Ajellomyces cap...  1122   0.0  
gb|EDL99005.1|  rCG22451 [Rattus norvegicus]                     1119   0.0  
gb|EDL00069.1|  aldehyde oxidase 3, isoform CRA_b [Mus muscu...  1116   0.0  
dbj|BAA21639.1|  xanthine dehydrogenase [Bombyx mori]            1100   0.0  
ref|XP_001797843.1|  hypothetical protein SNOG_07509 [Phaeos...  1093   0.0  
ref|XP_001408466.1|  hypothetical protein MGG_12738 [Magnapo...  1084   0.0  
gb|EAY90548.1|  hypothetical protein OsI_011781 [Oryza sativ...  1081   0.0  
gb|EEH40664.1|  aldehyde oxidoreductase [Paracoccidioides br...  1054   0.0  
dbj|BAB47182.1|  truncated xanthine dehydrogenase [Bombyx mori]  1050   0.0  
ref|XP_793571.2|  PREDICTED: similar to xanthine dehydrogena...  1038   0.0  
gb|EEH41343.1|  xanthine dehydrogenase [Paracoccidioides bra...  1033   0.0  
ref|XP_759411.1|  hypothetical protein UM03264.1 [Ustilago m...  1031   0.0  
ref|XP_001558086.1|  hypothetical protein BC1G_03118 [Botryo...  1027   0.0  
ref|XP_001694090.1|  xanthine dehydrogenase/oxidase [Chlamyd...  1018   0.0  
ref|XP_001261698.1|  xanthine dehydrogenase [Neosartorya fis...  1014   0.0  
ref|XP_001625891.1|  predicted protein [Nematostella vectens...  1010   0.0  
ref|XP_001505419.1|  PREDICTED: similar to xanthine oxidored...  1007   0.0  
ref|XP_001307869.1|  aldehyde oxidase and xanthine dehydroge...  1006   0.0  
ref|XP_001182218.1|  PREDICTED: similar to xanthine:oxygen o...  1004   0.0  
ref|XP_001390055.1|  hypothetical protein An03g01530 [Asperg...   998   0.0  
ref|XP_001590688.1|  hypothetical protein SS1G_08428 [Sclero...   995   0.0  
ref|XP_790508.2|  PREDICTED: similar to xanthine:oxygen oxid...   995   0.0  
emb|CAF95791.1|  unnamed protein product [Tetraodon nigrovir...   990   0.0  
ref|XP_682447.1|  hypothetical protein AN9178.2 [Aspergillus...   986   0.0  
ref|XP_001305898.1|  aldehyde oxidase and xanthine dehydroge...   974   0.0  
ref|XP_001539262.1|  xanthine dehydrogenase [Ajellomyces cap...   973   0.0  
emb|CAN75890.1|  hypothetical protein [Vitis vinifera]            950   0.0  
ref|XP_001217202.1|  xanthine dehydrogenase [Aspergillus ter...   942   0.0  
ref|XP_001625969.1|  predicted protein [Nematostella vectens...   930   0.0  
dbj|BAB23485.1|  unnamed protein product [Mus musculus]           924   0.0  
gb|EDU50617.1|  xanthine dehydrogenase/oxidase [Pyrenophora ...   903   0.0  
ref|XP_001794615.1|  hypothetical protein SNOG_04191 [Phaeos...   898   0.0  
gb|AAY24265.1|  unknown [Homo sapiens]                            886   0.0  
ref|YP_631346.1|  putative xanthine dehydrogenase [Myxococcu...   885   0.0  
gb|EEH50118.1|  xanthine dehydrogenase [Paracoccidioides bra...   880   0.0  
ref|ZP_02970663.1|  aldehyde oxidase and xanthine dehydrogen...   847   0.0  
gb|AAM11042.1|  GH08847p [Drosophila melanogaster]                823   0.0  
ref|XP_001584737.1|  hypothetical protein SS1G_14350 [Sclero...   808   0.0  
ref|XP_001660965.1|  xanthine dehydrogenase [Aedes aegypti] ...   797   0.0  
ref|XP_001497159.1|  PREDICTED: similar to aldehyde oxidase ...   796   0.0  
gb|EAW70211.1|  hCG1811467 [Homo sapiens]                         784   0.0  
gb|AAW31602.1|  xanthine dehydrogenase [Drosophila bifurca]       755   0.0  
gb|AAQ56084.1|  xanthine dehydrogenase [Drosophila bifurca]       752   0.0  
gb|AAF03928.1|AF093218_1  xanthine dehydrogenase [Ceratitis ...   750   0.0  
gb|AAW31604.1|  xanthine dehydrogenase [Drosophila guayllaba...   750   0.0  
gb|AAF82044.1|  xanthine dehydrogenase [Drosophila buzzatii]      749   0.0  
gb|AAW31601.1|  xanthine dehydrogenase [Drosophila novemaris...   748   0.0  
gb|AAF82041.1|  xanthine dehydrogenase [Drosophila starmeri]      746   0.0  
gb|AAF03925.1|AF093215_1  xanthine dehydrogenase [Drosophila...   746   0.0  
ref|XP_001326092.1|  aldehyde oxidase and xanthine dehydroge...   745   0.0  
gb|AAF82042.1|  xanthine dehydrogenase [Drosophila uniseta]       744   0.0  
gb|AAF82050.1|  xanthine dehydrogenase [Drosophila stalkeri]      744   0.0  
gb|AAF82051.1|  xanthine dehydrogenase [Drosophila mulleri]       743   0.0  
gb|AAF82040.1|  xanthine dehydrogenase [Drosophila martensis]     743   0.0  
gb|AAF03924.1|AF093214_1  xanthine dehydrogenase [Hirtodroso...   743   0.0  
gb|AAF03918.1|AF093208_1  xanthine dehydrogenase [Drosophila...   743   0.0  
gb|EDL00070.1|  aldehyde oxidase 4 [Mus musculus]                 743   0.0  
gb|AAF03920.1|AF093210_1  xanthine dehydrogenase [Drosophila...   742   0.0  
gb|AAF82046.1|  xanthine dehydrogenase [Drosophila borborema]     741   0.0  
gb|AAF82043.1|  xanthine dehydrogenase [Drosophila venezolana]    740   0.0  
gb|AAF03917.1|  xanthine dehydrogenase [Drosophila equinoxia...   739   0.0  
gb|AAF82048.1|  xanthine dehydrogenase [Drosophila koepferae]     739   0.0  
gb|AAF03919.1|AF093209_1  xanthine dehydrogenase [Drosophila...   738   0.0  
gb|AAF82047.1|  xanthine dehydrogenase [Drosophila koepferae]     738   0.0  
gb|AAF31666.1|AF169400_1  xanthine dehydrogenase [Drosophila...   737   0.0  
gb|AAF82049.1|  xanthine dehydrogenase [Drosophila richardsoni]   737   0.0  
gb|AAW31603.1|  xanthine dehydrogenase [Drosophila eohydei]       737   0.0  
gb|AAK97364.1|  xanthine dehydrogenase [Drosophila ananassae]     736   0.0  
gb|AAF29561.1|AF058980_1  xanthine dehydrogenase [Drosophila...   736   0.0  
gb|AAF82045.1|  xanthine dehydrogenase [Drosophila serido]        735   0.0  
gb|AAF03922.1|AF093212_1  xanthine dehydrogenase [Drosophila...   735   0.0  
gb|AAW31605.1|  xanthine dehydrogenase [Drosophila nigrohydei]    735   0.0  
gb|AAF82052.1|  xanthine dehydrogenase [Drosophila hydei]         733   0.0  
gb|EDL99006.1|  rCG22519, isoform CRA_a [Rattus norvegicus]       733   0.0  
gb|AAF29559.1|AF058978_1  xanthine dehydrogenase [Drosophila...   733   0.0  
gb|AAF03916.1|AF093206_1  xanthine dehydrogenase [Drosophila...   732   0.0  
gb|AAF03921.1|AF093211_1  xanthine dehydrogenase [Drosophila...   732   0.0  
gb|AAK97365.1|  xanthine dehydrogenase [Drosophila mimica]        732   0.0  
gb|AAF29563.1|AF058982_1  xanthine dehydrogenase [Drosophila...   731   0.0  
gb|AAF29560.1|AF058979_1  xanthine dehydrogenase [Drosophila...   731   0.0  
gb|AAF31667.1|  xanthine dehydrogenase [Drosophila teissieri]     730   0.0  
gb|AAF29564.1|  xanthine dehydrogenase [Drosophila sturtevanti]   729   0.0  
gb|AAF29565.1|AF058984_1  xanthine dehydrogenase [Scaptodros...   729   0.0  
gb|AAF03927.1|AF093217_1  xanthine dehydrogenase [Chymomyza ...   727   0.0  
gb|AAK97366.1|  xanthine dehydrogenase [Drosophila busckii]       727   0.0  
gb|AAF29562.1|AF058981_1  xanthine dehydrogenase [Drosophila...   726   0.0  
gb|AAF31665.1|  xanthine dehydrogenase [Drosophila bifasciata]    725   0.0  
gb|AAF03923.1|AF093213_1  xanthine dehydrogenase [Drosophila...   723   0.0  
gb|AAX13171.1|  rosy [Drosophila miranda]                         723   0.0  
gb|AAF03926.1|AF093216_1  xanthine dehydrogenase [Zaprionus ...   722   0.0  
gb|AAX13176.1|  rosy [Drosophila miranda] >gi|60100086|gb|AA...   721   0.0  
gb|AAX13175.1|  rosy [Drosophila miranda]                         720   0.0  
gb|AAX13168.1|  rosy [Drosophila miranda] >gi|60100070|gb|AA...   720   0.0  
gb|AAX13179.1|  rosy [Drosophila miranda]                         719   0.0  
gb|AAC64395.1|  xanthine dehydrogenase [Drosophila subobscura]    719   0.0  
gb|AAX13170.1|  rosy [Drosophila miranda] >gi|60100076|gb|AA...   719   0.0  
gb|AAX13174.1|  rosy [Drosophila miranda]                         718   0.0  
gb|AAX13173.1|  rosy [Drosophila miranda]                         717   0.0  
gb|AAX13180.1|  rosy [Drosophila pseudoobscura]                   717   0.0  
gb|AAX13167.1|  rosy [Drosophila affinis]                         710   0.0  
dbj|BAE42582.1|  unnamed protein product [Mus musculus]           691   0.0  
emb|CAG10297.1|  unnamed protein product [Tetraodon nigrovir...   673   0.0  
dbj|BAA24520.1|  xanthine dehydrogenase [Bombyx mori]             661   0.0  
ref|NP_189946.1|  AAO2 (ALDEHYDE OXIDASE 2) [Arabidopsis tha...   646   0.0  
gb|ABD74431.1|  xanthine dehydrogenase subunit B [Serratia p...   641   0.0  
ref|ZP_01221691.1|  putative xanthine dehydrogenase, XdhB su...   639   0.0  
ref|ZP_02186370.1|  aldehyde oxidase and xanthine dehydrogen...   637   e-180
ref|ZP_01307210.1|  xanthine dehydrogenase, molybdopterin bi...   635   e-180
dbj|BAB25715.1|  unnamed protein product [Mus musculus]           634   e-179
pdb|3B9J|B  Chain B, Structure Of Xanthine Oxidase With 2-Hy...   633   e-179
emb|CAA34962.2|  xanthine dehydrogenase [Calliphora vicina]       632   e-179
ref|YP_001478530.1|  Xanthine dehydrogenase molybdopterin bi...   632   e-179
ref|YP_130432.1|  putative xanthine dehydrogenase, XdhB subu...   632   e-179
ref|XP_001637029.1|  predicted protein [Nematostella vectens...   631   e-178
pdb|1FIQ|B  Chain B, Crystal Structure Of Xanthine Oxidase F...   630   e-178
gb|EEJ89840.1|  xanthine dehydrogenase, molybdenum binding s...   630   e-178
ref|ZP_01867052.1|  putative xanthine dehydrogenase, XdhB su...   628   e-178
gb|EEJ87317.1|  xanthine dehydrogenase, molybdenum binding s...   627   e-177
ref|YP_001173564.1|  xanthine dehydrogenase [Pseudomonas stu...   625   e-177
ref|ZP_01814682.1|  putative xanthine dehydrogenase, XdhB su...   622   e-176
ref|ZP_01364872.1|  hypothetical protein PaerPA_01001984 [Ps...   621   e-175
ref|ZP_00976444.1|  COG4631: Xanthine dehydrogenase, molybdo...   621   e-175
ref|YP_791730.1|  xanthine dehydrogenase [Pseudomonas aerugi...   621   e-175
ref|NP_250214.1|  xanthine dehydrogenase [Pseudomonas aerugi...   621   e-175
ref|ZP_00989875.1|  putative xanthine dehydrogenase, XdhB su...   620   e-175
ref|ZP_00970064.1|  COG4631: Xanthine dehydrogenase, molybdo...   620   e-175
ref|YP_001349164.1|  xanthine dehydrogenase, molybdopterin b...   620   e-175
ref|ZP_01893690.1|  xanthine dehydrogenase, molybdopterin bi...   612   e-173
ref|XP_001864334.1|  aldehyde oxidase [Culex pipiens quinque...   610   e-172
ref|NP_563711.1|  AAO4 (ALDEHYDE OXIDASE 4); aldehyde oxidas...   610   e-172
ref|ZP_01737083.1|  xanthine dehydrogenase, molybdopterin bi...   608   e-172
ref|YP_001188239.1|  Xanthine dehydrogenase [Pseudomonas men...   607   e-171
ref|ZP_01440729.1|  xanthine dehydrogenase, C-terminal subun...   604   e-170
ref|NP_421419.1|  xanthine dehydrogenase, C-terminal subunit...   603   e-170
ref|ZP_01905780.1|  Xanthine dehydrogenase [Plesiocystis pac...   603   e-170
ref|ZP_01898626.1|  putative xanthine dehydrogenase, XdhB su...   603   e-170
ref|YP_987305.1|  aldehyde oxidase and xanthine dehydrogenas...   602   e-170
ref|YP_594112.1|  Xanthine dehydrogenase [Deinococcus geothe...   602   e-170
ref|YP_191086.1|  Xanthine dehydrogenase XdhB protein [Gluco...   601   e-169
ref|YP_432403.1|  Xanthine dehydrogenase, molybdopterin-bind...   600   e-169
ref|XP_001864348.1|  xanthine dehydrogenase/oxidase [Culex p...   600   e-169
>gb|AAA75287.1| xanthine dehydrogenase
          Length = 1333

 Score = 2743 bits (7111), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1325/1333 (99%), Positives = 1326/1333 (99%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCG DGNNPNCC
Sbjct: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGRDGNNPNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS
Sbjct: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TLKELLDLKAQHPDAKLV GNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG
Sbjct: 241  TLKELLDLKAQHPDAKLVEGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLE +RWFAGKQVKSVASVGGNIITASPISD
Sbjct: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEHVRWFAGKQVKSVASVGGNIITASPISD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA
Sbjct: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE
Sbjct: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            ELLQDVCAGLAEEL LPPDAPGGMVDFRCTLTLS   KFYLTVLQKLGQENLEDKCGKLD
Sbjct: 481  ELLQDVCAGLAEELQLPPDAPGGMVDFRCTLTLSLLLKFYLTVLQKLGQENLEDKCGKLD 540

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY
Sbjct: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK
Sbjct: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL
Sbjct: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM
Sbjct: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR
Sbjct: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR
Sbjct: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL
Sbjct: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA
Sbjct: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA
Sbjct: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG
Sbjct: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV
Sbjct: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT
Sbjct: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320

Query: 1321 GVPENCKPWSVRV 1333
            GVPENCKPWSVRV
Sbjct: 1321 GVPENCKPWSVRV 1333
>ref|NP_000370.2| xanthine dehydrogenase [Homo sapiens]
 sp|P47989|XDH_HUMAN Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase
            (XD); Xanthine oxidase (XO) (Xanthine oxidoreductase)]
 pdb|2CKJ|A Chain A, Human Milk Xanthine Oxidoreductase
 pdb|2CKJ|B Chain B, Human Milk Xanthine Oxidoreductase
 pdb|2CKJ|C Chain C, Human Milk Xanthine Oxidoreductase
 pdb|2CKJ|D Chain D, Human Milk Xanthine Oxidoreductase
 gb|AAB08399.1| xanthine dehydrogenase/oxidase [Homo sapiens]
 dbj|BAA02013.2| xanthine dehydrogenase [Homo sapiens]
 gb|AAY68219.1| xanthine dehydrogenase [Homo sapiens]
 gb|EAX00479.1| xanthine dehydrogenase [Homo sapiens]
 gb|AAI66696.1| Xanthine dehydrogenase [synthetic construct]
          Length = 1333

 Score = 2729 bits (7074), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1333/1333 (100%), Positives = 1333/1333 (100%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC
Sbjct: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS
Sbjct: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG
Sbjct: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD
Sbjct: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA
Sbjct: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE
Sbjct: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD
Sbjct: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY
Sbjct: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK
Sbjct: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL
Sbjct: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM
Sbjct: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR
Sbjct: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR
Sbjct: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL
Sbjct: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA
Sbjct: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA
Sbjct: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG
Sbjct: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV
Sbjct: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT
Sbjct: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320

Query: 1321 GVPENCKPWSVRV 1333
            GVPENCKPWSVRV
Sbjct: 1321 GVPENCKPWSVRV 1333
>pdb|2E1Q|A Chain A, Crystal Structure Of Human Xanthine Oxidoreductase Mutant,
            Glu803val
 pdb|2E1Q|B Chain B, Crystal Structure Of Human Xanthine Oxidoreductase Mutant,
            Glu803val
 pdb|2E1Q|C Chain C, Crystal Structure Of Human Xanthine Oxidoreductase Mutant,
            Glu803val
 pdb|2E1Q|D Chain D, Crystal Structure Of Human Xanthine Oxidoreductase Mutant,
            Glu803val
          Length = 1333

 Score = 2726 bits (7067), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1332/1333 (99%), Positives = 1332/1333 (99%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC
Sbjct: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS
Sbjct: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG
Sbjct: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD
Sbjct: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA
Sbjct: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE
Sbjct: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD
Sbjct: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY
Sbjct: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK
Sbjct: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL
Sbjct: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM
Sbjct: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVPANRIVVRVKRMGGGFGGK TRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR
Sbjct: 781  LGVPANRIVVRVKRMGGGFGGKVTRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR
Sbjct: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL
Sbjct: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA
Sbjct: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA
Sbjct: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG
Sbjct: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV
Sbjct: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT
Sbjct: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320

Query: 1321 GVPENCKPWSVRV 1333
            GVPENCKPWSVRV
Sbjct: 1321 GVPENCKPWSVRV 1333
>ref|XP_525729.2| PREDICTED: xanthine dehydrogenase [Pan troglodytes]
          Length = 1333

 Score = 2717 bits (7042), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1326/1333 (99%), Positives = 1329/1333 (99%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC
Sbjct: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS
Sbjct: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG
Sbjct: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD
Sbjct: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA
Sbjct: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLW+E
Sbjct: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWQE 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD
Sbjct: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PTFASATLLF +DPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY
Sbjct: 541  PTFASATLLFHRDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
             NELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK
Sbjct: 601  GNELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL
Sbjct: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM
Sbjct: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR
Sbjct: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTG VVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR
Sbjct: 841  HPFLARYKVGFMKTGMVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL
Sbjct: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA
Sbjct: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA
Sbjct: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG
Sbjct: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGN FHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1141 YSFETNSGNAFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV
Sbjct: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT
Sbjct: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320

Query: 1321 GVPENCKPWSVRV 1333
            GVPENCKPWSVRV
Sbjct: 1321 GVPENCKPWSVRV 1333
>ref|NP_001116410.1| xanthine dehydrogenase/oxidase [Oryctolagus cuniculus]
 gb|ABY47889.1| xanthine dehydrogenase/oxidase [Oryctolagus cuniculus]
          Length = 1333

 Score = 2559 bits (6632), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1240/1333 (93%), Positives = 1288/1333 (96%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYD 
Sbjct: 1    MTADELVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDH 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMY LLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG G+NPNCC
Sbjct: 121  VMSMYMLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFAQDGGCCGGSGDNPNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQ+K+  V+LSPSLFKPEEF PLDPTQEPIFPPELLRLKDTPR+QLRFEGERVTWIQAS
Sbjct: 181  MNQRKEQRVTLSPSLFKPEEFAPLDPTQEPIFPPELLRLKDTPRRQLRFEGERVTWIQAS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TL ELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGP+GI+FG
Sbjct: 241  TLGELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPEGITFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            AACPLS VEKTLVDAVAKLP QKTEVFRGVLEQLRWFAGKQVKSVAS+GGNIITASPISD
Sbjct: 301  AACPLSSVEKTLVDAVAKLPVQKTEVFRGVLEQLRWFAGKQVKSVASIGGNIITASPISD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLTLVSRGTRRTV+MDHTFFPGYR+TLL+PEEILLSIEIPYSREGE+FSA
Sbjct: 361  LNPVFMASGAKLTLVSRGTRRTVRMDHTFFPGYRRTLLNPEEILLSIEIPYSREGEFFSA 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVT GMRVLFKPG+ EV+ELALCYGGMANRTISALKTTQRQ++K W  
Sbjct: 421  FKQASRREDDIAKVTCGMRVLFKPGSMEVKELALCYGGMANRTISALKTTQRQIAKSWGP 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            ELLQ+VCAGLA+EL LP DAPGGMV+FR TL+LSFFFKFYLTVLQKLG EN +DKC  LD
Sbjct: 481  ELLQEVCAGLADELQLPADAPGGMVEFRRTLSLSFFFKFYLTVLQKLGGENPDDKCSLLD 540

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PTFASATLLFQKDPPA+VQLFQEVPKGQSEEDMVGRPLPHLAA MQASGEAVYCDDIPRY
Sbjct: 541  PTFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPLPHLAAGMQASGEAVYCDDIPRY 600

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENELSLRLVTSTRAHAKIKSID S AKKVPGFVCF+SA D+PGSN+TG+CNDETVFA+DK
Sbjct: 601  ENELSLRLVTSTRAHAKIKSIDISVAKKVPGFVCFLSAADIPGSNVTGLCNDETVFAQDK 660

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVV DTPEH QRAAQGVKITYE+LPAIITIEDAIKN SFYGPELKIEKGDL
Sbjct: 661  VTCVGHIIGAVVTDTPEHAQRAAQGVKITYEDLPAIITIEDAIKNESFYGPELKIEKGDL 720

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVA M
Sbjct: 721  KKGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVANM 780

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR
Sbjct: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTG VVALEV+HFSN GNTQDLSQ IMERALFHMDNCYKIPNIRGTGR
Sbjct: 841  HPFLARYKVGFMKTGKVVALEVEHFSNAGNTQDLSQGIMERALFHMDNCYKIPNIRGTGR 900

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            LCKTNLPSNTAFRGFGGPQGMLIAE WMSEVA TCG+PAE+VRRKN+YKEGDLTHFNQKL
Sbjct: 901  LCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVATTCGLPAEDVRRKNMYKEGDLTHFNQKL 960

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTLPRCW+ECLASSQ+ ARKSEVDKFNKENCWKKRGL IIPTKFGISFTVPFLNQAGA
Sbjct: 961  EGFTLPRCWDECLASSQFEARKSEVDKFNKENCWKKRGLSIIPTKFGISFTVPFLNQAGA 1020

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETST+TVPNTSPTAA
Sbjct: 1021 LVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTSTVPNTSPTAA 1080

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVSAD+NGQAVY ACQTILKRLEP+KKKNPSGSWEDWVTAAY+D VSLSATGFY+TPNLG
Sbjct: 1081 SVSADINGQAVYEACQTILKRLEPFKKKNPSGSWEDWVTAAYLDAVSLSATGFYKTPNLG 1140

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPFHYF+YGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1141 YSFETNSGNPFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV
Sbjct: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLAASIFFAIKDAIRAAR+QHT  N K LFRLDSPATPEKIRNACVD+FTTLCVT
Sbjct: 1261 GEPPLFLAASIFFAIKDAIRAARSQHTDYNTKPLFRLDSPATPEKIRNACVDQFTTLCVT 1320

Query: 1321 GVPENCKPWSVRV 1333
            G  ENCKPW+ RV
Sbjct: 1321 GEVENCKPWAQRV 1333
>ref|XP_001501608.1| PREDICTED: similar to xanthine dehydrogenase/oxidase [Equus caballus]
          Length = 1333

 Score = 2531 bits (6560), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1219/1333 (91%), Positives = 1283/1333 (96%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVM SKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMFSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIE+AFQGNLCRCTGYRPILQGFRTFARDGGCCGG G+NPNCC
Sbjct: 121  VMSMYTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRTFARDGGCCGGKGDNPNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQKKD  V+LSPSLF PEEF PLDPTQEPIFPPELLRLKD P+KQLRFEGERVTWIQAS
Sbjct: 181  MNQKKDQMVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDAPQKQLRFEGERVTWIQAS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFP+IVCPAWIPELNSVEHG +GISFG
Sbjct: 241  TLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPLIVCPAWIPELNSVEHGEEGISFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            A+CPLS VEKTL+DAVA+LP  KTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD
Sbjct: 301  ASCPLSCVEKTLLDAVAQLPTYKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLT+VSRGTRRT++MDHTFFPGYRKTLL PEEILL+IEIPYSREGE+FSA
Sbjct: 361  LNPVFMASGAKLTMVSRGTRRTIRMDHTFFPGYRKTLLGPEEILLAIEIPYSREGEFFSA 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVTSGMRVLFKPGTT+++ELALCYGGMA+RTISALKTT++QLSK W E
Sbjct: 421  FKQASRREDDIAKVTSGMRVLFKPGTTQIEELALCYGGMADRTISALKTTRKQLSKFWNE 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            ELLQDVCAGLAEEL L PDAPGGM++FR TLTLSFFFKFYLTVLQKLG+ + ED+CGKLD
Sbjct: 481  ELLQDVCAGLAEELQLAPDAPGGMIEFRRTLTLSFFFKFYLTVLQKLGKVDSEDQCGKLD 540

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PT ASATLLFQKDPPA+VQLFQEVPKGQSEEDMVGRPLPHL A MQA GEAVYCDDIPRY
Sbjct: 541  PTCASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPLPHLGASMQACGEAVYCDDIPRY 600

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            +NELSLRLVTSTRAHAKIKSIDTSEA+KVPGFVCF+SADD+PGSN TG+ NDETVFAKD+
Sbjct: 601  QNELSLRLVTSTRAHAKIKSIDTSEAQKVPGFVCFVSADDIPGSNKTGLFNDETVFAKDE 660

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVV DTPEH QRAAQ VKITYE+LPAIITIEDAIK+NSFYG   KIEKGDL
Sbjct: 661  VTCVGHIIGAVVTDTPEHAQRAAQAVKITYEDLPAIITIEDAIKHNSFYGSGRKIEKGDL 720

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGF EADN+VSGE YIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQ+FVAK+
Sbjct: 721  KKGFLEADNIVSGEFYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQAFVAKV 780

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVPANR++VRVKR+GGGFGGKETRSTVVSTAVALAAYKTG PVRCMLDRDEDMLITGGR
Sbjct: 781  LGVPANRVLVRVKRLGGGFGGKETRSTVVSTAVALAAYKTGCPVRCMLDRDEDMLITGGR 840

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTG +VALEVDH+SN GNT DLS++IM+RALFHMDNCYKIPNIRGTGR
Sbjct: 841  HPFLARYKVGFMKTGRIVALEVDHYSNAGNTLDLSEAIMDRALFHMDNCYKIPNIRGTGR 900

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            LCKTNLPSNTAFRGFGGPQGMLIAE WMSEVAVTCG+PAEEVRRKN+YKEGDLTHFNQKL
Sbjct: 901  LCKTNLPSNTAFRGFGGPQGMLIAEQWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKL 960

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTL RCW+ECLASSQYHARKSE+DKFNKENCWKKRGLCI+PTKFGISFTV FLNQAGA
Sbjct: 961  EGFTLTRCWDECLASSQYHARKSEIDKFNKENCWKKRGLCIVPTKFGISFTVSFLNQAGA 1020

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA
Sbjct: 1021 LIHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVS DLNGQAVY ACQTILKRLEP+K+KNPSGSWEDWV AAY D VSLSATGFY+TPNLG
Sbjct: 1081 SVSTDLNGQAVYEACQTILKRLEPFKRKNPSGSWEDWVLAAYQDAVSLSATGFYKTPNLG 1140

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFTLEEL YSPEGSL+TRGPSTYKIPAFGSIPIEFRVSLLRD PNKKAIYASKA+
Sbjct: 1201 VQGLGLFTLEELQYSPEGSLYTRGPSTYKIPAFGSIPIEFRVSLLRDSPNKKAIYASKAI 1260

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLA+SIFFAIKDAIRAARAQH+ NN+KELFRLDSPATPEKIRNACVDKFTTLCVT
Sbjct: 1261 GEPPLFLASSIFFAIKDAIRAARAQHSDNNIKELFRLDSPATPEKIRNACVDKFTTLCVT 1320

Query: 1321 GVPENCKPWSVRV 1333
            GVPENCK WS+RV
Sbjct: 1321 GVPENCKAWSLRV 1333
>ref|XP_540143.2| PREDICTED: similar to Xanthine dehydrogenase/oxidase isoform 1 [Canis
            familiaris]
          Length = 1333

 Score = 2511 bits (6509), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1207/1334 (90%), Positives = 1273/1334 (95%), Gaps = 2/1334 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKL LSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
             QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTK+RLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   FQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG  +NPNCC
Sbjct: 121  VMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSRDNPNCC 180

Query: 181  MNQKKDHS-VSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQA 239
            +NQKKD S V LSPSLF PEEF PLDPTQEPIFPPELLRLKD P+KQL F+GERVTWIQA
Sbjct: 181  LNQKKDCSRVILSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPQKQLCFKGERVTWIQA 240

Query: 240  STLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISF 299
            STLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMIVCPAWIPELN+VEHG +GISF
Sbjct: 241  STLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEGISF 300

Query: 300  GAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPIS 359
            GAACPLSIVEKTL DAV KLPA KTEVF+GVLEQLRWFAGKQVKSVAS+GGNII ASPIS
Sbjct: 301  GAACPLSIVEKTLHDAVNKLPAYKTEVFKGVLEQLRWFAGKQVKSVASIGGNIINASPIS 360

Query: 360  DLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFS 419
            DLNPVFMAS AKLT+VSRG +RTV+MDHTFFPGYRKTLL+PEEILLSIEIPYSREGE+FS
Sbjct: 361  DLNPVFMASEAKLTIVSRGIKRTVRMDHTFFPGYRKTLLAPEEILLSIEIPYSREGEFFS 420

Query: 420  AFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWK 479
            AFKQASRREDDIAKVTSGMRVLF PGT +V+ELALCYGGM +RTISALKTT++Q+  LW 
Sbjct: 421  AFKQASRREDDIAKVTSGMRVLFHPGTAQVKELALCYGGMDDRTISALKTTRKQVENLWN 480

Query: 480  EELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKL 539
            E+LLQ+VCAGLAEEL L PDAPGGMVDFR TLTLSFFFKFYLTVLQKL + NLE+KCGKL
Sbjct: 481  EDLLQNVCAGLAEELKLSPDAPGGMVDFRRTLTLSFFFKFYLTVLQKLERGNLENKCGKL 540

Query: 540  DPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPR 599
            DPT+ASATLLFQKDPPA+VQLFQEVP+GQSEEDMVGRPLPHLAA MQASGEAVYCDDIPR
Sbjct: 541  DPTYASATLLFQKDPPANVQLFQEVPEGQSEEDMVGRPLPHLAAAMQASGEAVYCDDIPR 600

Query: 600  YENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKD 659
            YENELSLRLVTSTRAHAKIKSIDTSEA+KVPGFVCF+S +DVPGSN TGI NDET+FA+D
Sbjct: 601  YENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKTGIFNDETIFAED 660

Query: 660  KVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGD 719
            +VTC+GHIIGAVV DTPEH QRAAQGVKITYEELPAIITIEDAIKNNSFYG ELKIEKG+
Sbjct: 661  EVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAIKNNSFYGSELKIEKGE 720

Query: 720  LKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAK 779
            L KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGE GE+ELF STQNTMKTQ+FVA 
Sbjct: 721  LTKGFSEADNVVSGEVYIGGQEHFYLETHCTIAVPKGEEGELELFASTQNTMKTQAFVAN 780

Query: 780  MLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGG 839
            MLGVP NRI+VRVKRMGGGFGGKETRST+VST VALAAYKTGRPVRCMLDRDEDMLITGG
Sbjct: 781  MLGVPINRILVRVKRMGGGFGGKETRSTLVSTVVALAAYKTGRPVRCMLDRDEDMLITGG 840

Query: 840  RHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTG 899
            RHPFLA+YKVGFMKTG VVALEV+H+SN GNT DLSQSIMERALFHMDNCYKIPNIRGTG
Sbjct: 841  RHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERALFHMDNCYKIPNIRGTG 900

Query: 900  RLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQK 959
            RLCKTNLPSNTAFRGFGGPQGMLIAE WMSEVA+TCG+PAEEVRRKN+YKEGDLTHFNQK
Sbjct: 901  RLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGDLTHFNQK 960

Query: 960  LEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAG 1019
            LEGFTL RCWEECLASSQYHARKSEVDKFN+EN WKKRGLCIIPTKFGISFT+ FLNQAG
Sbjct: 961  LEGFTLSRCWEECLASSQYHARKSEVDKFNEENYWKKRGLCIIPTKFGISFTLSFLNQAG 1020

Query: 1020 ALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTA 1079
            AL+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTA
Sbjct: 1021 ALIHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTA 1080

Query: 1080 ASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNL 1139
            ASVSAD+NGQAVY AC+TILKRLEP+KKKNPSGSWEDWV  AY +TVSLSATGFYRTPNL
Sbjct: 1081 ASVSADINGQAVYEACKTILKRLEPFKKKNPSGSWEDWVIDAYENTVSLSATGFYRTPNL 1140

Query: 1140 GYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGA 1199
            GYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGA
Sbjct: 1141 GYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGA 1200

Query: 1200 FVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKA 1259
            FVQGLGLFTLEELHYSPEGSL TRGPSTYKIPAFG+IP EFRVSLLRDCPNKKAIYASKA
Sbjct: 1201 FVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRDCPNKKAIYASKA 1260

Query: 1260 VGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCV 1319
            VGEPPLFLAAS+FFAIKDA+RAARA+++    K LFRLDSPATPEKIRNACVD+FTTLCV
Sbjct: 1261 VGEPPLFLAASVFFAIKDAVRAARARNSDCKTK-LFRLDSPATPEKIRNACVDEFTTLCV 1319

Query: 1320 TGVPENCKPWSVRV 1333
            TG+PENCKPWSVRV
Sbjct: 1320 TGIPENCKPWSVRV 1333
>ref|NP_001009217.1| xanthine dehydrogenase [Felis catus]
 sp|Q9MYW6|XDH_FELCA Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase
            (XD); Xanthine oxidase (XO) (Xanthine oxidoreductase)]
 gb|AAF97949.1|AF286379_1 xanthine dehydrogenase [Felis catus]
          Length = 1331

 Score = 2511 bits (6507), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1206/1333 (90%), Positives = 1269/1333 (95%), Gaps = 2/1333 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
             QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTK+RLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   FQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIE+AFQGNLCRCTGYRPILQGFRTFARDGGCCGG GN+ NCC
Sbjct: 121  VMSMYTLLRNQPEPTIEEIEDAFQGNLCRCTGYRPILQGFRTFARDGGCCGGSGNDLNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQK DH ++LSPSLF PEEFTPLDPTQEPIFPPELLRLKDTP+KQLRFEGERVTWIQAS
Sbjct: 181  MNQKTDHKITLSPSLFNPEEFTPLDPTQEPIFPPELLRLKDTPQKQLRFEGERVTWIQAS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TL+ELLDLKAQ P+AKLVVGNTEIGIEMKFKNMLFP +VCPAWIPE   VEHGP+GISFG
Sbjct: 241  TLQELLDLKAQDPEAKLVVGNTEIGIEMKFKNMLFPKMVCPAWIPE--PVEHGPEGISFG 298

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            A+CPLS+VEKTL+DAVA LPA +TEVF+GVLEQLRWFAGKQVKSVAS+GGNIITASPISD
Sbjct: 299  ASCPLSLVEKTLLDAVANLPAHQTEVFKGVLEQLRWFAGKQVKSVASIGGNIITASPISD 358

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLT+VS GTRRTV+MDHTFFP YRKTLL+PEEILLSIEIPYSREGEYFSA
Sbjct: 359  LNPVFMASGAKLTIVSTGTRRTVRMDHTFFPAYRKTLLAPEEILLSIEIPYSREGEYFSA 418

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVTSGMRVLF PGT +V+ELALCYGGM +RT+SAL+TT++Q+S  W E
Sbjct: 419  FKQASRREDDIAKVTSGMRVLFNPGTAQVKELALCYGGMHDRTVSALQTTRKQISNFWNE 478

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            ELLQ+VCAGLAEEL L PDAPGGMV+FR TLTLSFFFKFYLTVLQKLG +N +DKCGKLD
Sbjct: 479  ELLQNVCAGLAEELSLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGIQNSKDKCGKLD 538

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PT ASATLLFQKDPPA+VQLFQEVPKGQ EEDMVGRPLPHLAA MQASGEAVYCDDIPRY
Sbjct: 539  PTHASATLLFQKDPPANVQLFQEVPKGQCEEDMVGRPLPHLAAAMQASGEAVYCDDIPRY 598

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENELSLRLVTSTRAHAKIKSIDTSEA+KVPGFVCFISADDVPGSNITGI NDE VFAKDK
Sbjct: 599  ENELSLRLVTSTRAHAKIKSIDTSEAQKVPGFVCFISADDVPGSNITGIGNDEMVFAKDK 658

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTC+GHIIGAVV DT EH QRAAQ V+ITYE+LPAIITIEDAI  +SFY PELKIEKG+L
Sbjct: 659  VTCIGHIIGAVVTDTREHAQRAAQAVRITYEDLPAIITIEDAIAKDSFYEPELKIEKGNL 718

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
             KGFSEADN+VSGE+YIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNT KTQSFVA M
Sbjct: 719  TKGFSEADNIVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTTKTQSFVANM 778

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVPANRI+VRVKRMGGGFGGKETRSTVVSTAV LAAYKTGRPVRCMLDRDEDMLITGGR
Sbjct: 779  LGVPANRILVRVKRMGGGFGGKETRSTVVSTAVPLAAYKTGRPVRCMLDRDEDMLITGGR 838

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTG VVAL+V+H+SN GNT DLSQSIMERALFHMDNCY IPNIRGTGR
Sbjct: 839  HPFLARYKVGFMKTGRVVALKVEHYSNAGNTLDLSQSIMERALFHMDNCYNIPNIRGTGR 898

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            +CKTNLPSNTAFRGFGGPQGMLIAE WMSEVAVTCG+PAEEVRRKN+YKEGDLTHFNQKL
Sbjct: 899  ICKTNLPSNTAFRGFGGPQGMLIAEHWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKL 958

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTLPRCWEECLASSQYHARK E DKFN+ENCWKKRGL IIPTKFGISFTVPFLNQAGA
Sbjct: 959  EGFTLPRCWEECLASSQYHARKREADKFNEENCWKKRGLSIIPTKFGISFTVPFLNQAGA 1018

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA
Sbjct: 1019 LVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1078

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVS D+NGQAVY ACQTILKRLEP+KKKNPSGSWEDWVTAAY+D VSLSATGFY+TPN+G
Sbjct: 1079 SVSTDINGQAVYEACQTILKRLEPFKKKNPSGSWEDWVTAAYLDAVSLSATGFYKTPNIG 1138

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1139 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1198

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIP EFRVSLLRDCPNKKAIYASKAV
Sbjct: 1199 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPSEFRVSLLRDCPNKKAIYASKAV 1258

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLAASIFFAIKDAI AARA +     K+LF+L+SPATPEKIRNACVD+FT LCVT
Sbjct: 1259 GEPPLFLAASIFFAIKDAICAARAGNPDCKTKKLFQLNSPATPEKIRNACVDQFTRLCVT 1318

Query: 1321 GVPENCKPWSVRV 1333
            G  E+CKPWSVRV
Sbjct: 1319 GTAESCKPWSVRV 1331
>ref|XP_862631.1| PREDICTED: similar to Xanthine dehydrogenase/oxidase isoform 6 [Canis
            familiaris]
          Length = 1334

 Score = 2510 bits (6505), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1207/1335 (90%), Positives = 1273/1335 (95%), Gaps = 3/1335 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKL LSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
             QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTK+RLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   FQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG  +NPNCC
Sbjct: 121  VMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSRDNPNCC 180

Query: 181  MNQKKDHS--VSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQ 238
            +NQKKD S  V LSPSLF PEEF PLDPTQEPIFPPELLRLKD P+KQL F+GERVTWIQ
Sbjct: 181  LNQKKDCSERVILSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPQKQLCFKGERVTWIQ 240

Query: 239  ASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGIS 298
            ASTLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMIVCPAWIPELN+VEHG +GIS
Sbjct: 241  ASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEGIS 300

Query: 299  FGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPI 358
            FGAACPLSIVEKTL DAV KLPA KTEVF+GVLEQLRWFAGKQVKSVAS+GGNII ASPI
Sbjct: 301  FGAACPLSIVEKTLHDAVNKLPAYKTEVFKGVLEQLRWFAGKQVKSVASIGGNIINASPI 360

Query: 359  SDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYF 418
            SDLNPVFMAS AKLT+VSRG +RTV+MDHTFFPGYRKTLL+PEEILLSIEIPYSREGE+F
Sbjct: 361  SDLNPVFMASEAKLTIVSRGIKRTVRMDHTFFPGYRKTLLAPEEILLSIEIPYSREGEFF 420

Query: 419  SAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLW 478
            SAFKQASRREDDIAKVTSGMRVLF PGT +V+ELALCYGGM +RTISALKTT++Q+  LW
Sbjct: 421  SAFKQASRREDDIAKVTSGMRVLFHPGTAQVKELALCYGGMDDRTISALKTTRKQVENLW 480

Query: 479  KEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGK 538
             E+LLQ+VCAGLAEEL L PDAPGGMVDFR TLTLSFFFKFYLTVLQKL + NLE+KCGK
Sbjct: 481  NEDLLQNVCAGLAEELKLSPDAPGGMVDFRRTLTLSFFFKFYLTVLQKLERGNLENKCGK 540

Query: 539  LDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIP 598
            LDPT+ASATLLFQKDPPA+VQLFQEVP+GQSEEDMVGRPLPHLAA MQASGEAVYCDDIP
Sbjct: 541  LDPTYASATLLFQKDPPANVQLFQEVPEGQSEEDMVGRPLPHLAAAMQASGEAVYCDDIP 600

Query: 599  RYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAK 658
            RYENELSLRLVTSTRAHAKIKSIDTSEA+KVPGFVCF+S +DVPGSN TGI NDET+FA+
Sbjct: 601  RYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKTGIFNDETIFAE 660

Query: 659  DKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKG 718
            D+VTC+GHIIGAVV DTPEH QRAAQGVKITYEELPAIITIEDAIKNNSFYG ELKIEKG
Sbjct: 661  DEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAIKNNSFYGSELKIEKG 720

Query: 719  DLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVA 778
            +L KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGE GE+ELF STQNTMKTQ+FVA
Sbjct: 721  ELTKGFSEADNVVSGEVYIGGQEHFYLETHCTIAVPKGEEGELELFASTQNTMKTQAFVA 780

Query: 779  KMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITG 838
             MLGVP NRI+VRVKRMGGGFGGKETRST+VST VALAAYKTGRPVRCMLDRDEDMLITG
Sbjct: 781  NMLGVPINRILVRVKRMGGGFGGKETRSTLVSTVVALAAYKTGRPVRCMLDRDEDMLITG 840

Query: 839  GRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGT 898
            GRHPFLA+YKVGFMKTG VVALEV+H+SN GNT DLSQSIMERALFHMDNCYKIPNIRGT
Sbjct: 841  GRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERALFHMDNCYKIPNIRGT 900

Query: 899  GRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQ 958
            GRLCKTNLPSNTAFRGFGGPQGMLIAE WMSEVA+TCG+PAEEVRRKN+YKEGDLTHFNQ
Sbjct: 901  GRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGDLTHFNQ 960

Query: 959  KLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQA 1018
            KLEGFTL RCWEECLASSQYHARKSEVDKFN+EN WKKRGLCIIPTKFGISFT+ FLNQA
Sbjct: 961  KLEGFTLSRCWEECLASSQYHARKSEVDKFNEENYWKKRGLCIIPTKFGISFTLSFLNQA 1020

Query: 1019 GALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPT 1078
            GAL+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPT
Sbjct: 1021 GALIHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPT 1080

Query: 1079 AASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPN 1138
            AASVSAD+NGQAVY AC+TILKRLEP+KKKNPSGSWEDWV  AY +TVSLSATGFYRTPN
Sbjct: 1081 AASVSADINGQAVYEACKTILKRLEPFKKKNPSGSWEDWVIDAYENTVSLSATGFYRTPN 1140

Query: 1139 LGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEG 1198
            LGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEG
Sbjct: 1141 LGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEG 1200

Query: 1199 AFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASK 1258
            AFVQGLGLFTLEELHYSPEGSL TRGPSTYKIPAFG+IP EFRVSLLRDCPNKKAIYASK
Sbjct: 1201 AFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRDCPNKKAIYASK 1260

Query: 1259 AVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLC 1318
            AVGEPPLFLAAS+FFAIKDA+RAARA+++    K LFRLDSPATPEKIRNACVD+FTTLC
Sbjct: 1261 AVGEPPLFLAASVFFAIKDAVRAARARNSDCKTK-LFRLDSPATPEKIRNACVDEFTTLC 1319

Query: 1319 VTGVPENCKPWSVRV 1333
            VTG+PENCKPWSVRV
Sbjct: 1320 VTGIPENCKPWSVRV 1334
>ref|XP_862539.1| PREDICTED: similar to Xanthine dehydrogenase/oxidase isoform 2 [Canis
            familiaris]
          Length = 1336

 Score = 2509 bits (6503), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1207/1337 (90%), Positives = 1273/1337 (95%), Gaps = 5/1337 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKL LSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
             QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTK+RLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   FQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG  +NPNCC
Sbjct: 121  VMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSRDNPNCC 180

Query: 181  MNQKKDHS----VSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTW 236
            +NQKKD S    V LSPSLF PEEF PLDPTQEPIFPPELLRLKD P+KQL F+GERVTW
Sbjct: 181  LNQKKDCSGGARVILSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPQKQLCFKGERVTW 240

Query: 237  IQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDG 296
            IQASTLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMIVCPAWIPELN+VEHG +G
Sbjct: 241  IQASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEG 300

Query: 297  ISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITAS 356
            ISFGAACPLSIVEKTL DAV KLPA KTEVF+GVLEQLRWFAGKQVKSVAS+GGNII AS
Sbjct: 301  ISFGAACPLSIVEKTLHDAVNKLPAYKTEVFKGVLEQLRWFAGKQVKSVASIGGNIINAS 360

Query: 357  PISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGE 416
            PISDLNPVFMAS AKLT+VSRG +RTV+MDHTFFPGYRKTLL+PEEILLSIEIPYSREGE
Sbjct: 361  PISDLNPVFMASEAKLTIVSRGIKRTVRMDHTFFPGYRKTLLAPEEILLSIEIPYSREGE 420

Query: 417  YFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSK 476
            +FSAFKQASRREDDIAKVTSGMRVLF PGT +V+ELALCYGGM +RTISALKTT++Q+  
Sbjct: 421  FFSAFKQASRREDDIAKVTSGMRVLFHPGTAQVKELALCYGGMDDRTISALKTTRKQVEN 480

Query: 477  LWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKC 536
            LW E+LLQ+VCAGLAEEL L PDAPGGMVDFR TLTLSFFFKFYLTVLQKL + NLE+KC
Sbjct: 481  LWNEDLLQNVCAGLAEELKLSPDAPGGMVDFRRTLTLSFFFKFYLTVLQKLERGNLENKC 540

Query: 537  GKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDD 596
            GKLDPT+ASATLLFQKDPPA+VQLFQEVP+GQSEEDMVGRPLPHLAA MQASGEAVYCDD
Sbjct: 541  GKLDPTYASATLLFQKDPPANVQLFQEVPEGQSEEDMVGRPLPHLAAAMQASGEAVYCDD 600

Query: 597  IPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVF 656
            IPRYENELSLRLVTSTRAHAKIKSIDTSEA+KVPGFVCF+S +DVPGSN TGI NDET+F
Sbjct: 601  IPRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKTGIFNDETIF 660

Query: 657  AKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIE 716
            A+D+VTC+GHIIGAVV DTPEH QRAAQGVKITYEELPAIITIEDAIKNNSFYG ELKIE
Sbjct: 661  AEDEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAIKNNSFYGSELKIE 720

Query: 717  KGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSF 776
            KG+L KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGE GE+ELF STQNTMKTQ+F
Sbjct: 721  KGELTKGFSEADNVVSGEVYIGGQEHFYLETHCTIAVPKGEEGELELFASTQNTMKTQAF 780

Query: 777  VAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLI 836
            VA MLGVP NRI+VRVKRMGGGFGGKETRST+VST VALAAYKTGRPVRCMLDRDEDMLI
Sbjct: 781  VANMLGVPINRILVRVKRMGGGFGGKETRSTLVSTVVALAAYKTGRPVRCMLDRDEDMLI 840

Query: 837  TGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIR 896
            TGGRHPFLA+YKVGFMKTG VVALEV+H+SN GNT DLSQSIMERALFHMDNCYKIPNIR
Sbjct: 841  TGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERALFHMDNCYKIPNIR 900

Query: 897  GTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHF 956
            GTGRLCKTNLPSNTAFRGFGGPQGMLIAE WMSEVA+TCG+PAEEVRRKN+YKEGDLTHF
Sbjct: 901  GTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGDLTHF 960

Query: 957  NQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLN 1016
            NQKLEGFTL RCWEECLASSQYHARKSEVDKFN+EN WKKRGLCIIPTKFGISFT+ FLN
Sbjct: 961  NQKLEGFTLSRCWEECLASSQYHARKSEVDKFNEENYWKKRGLCIIPTKFGISFTLSFLN 1020

Query: 1017 QAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTS 1076
            QAGAL+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTS
Sbjct: 1021 QAGALIHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTS 1080

Query: 1077 PTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRT 1136
            PTAASVSAD+NGQAVY AC+TILKRLEP+KKKNPSGSWEDWV  AY +TVSLSATGFYRT
Sbjct: 1081 PTAASVSADINGQAVYEACKTILKRLEPFKKKNPSGSWEDWVIDAYENTVSLSATGFYRT 1140

Query: 1137 PNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQV 1196
            PNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQV
Sbjct: 1141 PNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQV 1200

Query: 1197 EGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYA 1256
            EGAFVQGLGLFTLEELHYSPEGSL TRGPSTYKIPAFG+IP EFRVSLLRDCPNKKAIYA
Sbjct: 1201 EGAFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRDCPNKKAIYA 1260

Query: 1257 SKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTT 1316
            SKAVGEPPLFLAAS+FFAIKDA+RAARA+++    K LFRLDSPATPEKIRNACVD+FTT
Sbjct: 1261 SKAVGEPPLFLAASVFFAIKDAVRAARARNSDCKTK-LFRLDSPATPEKIRNACVDEFTT 1319

Query: 1317 LCVTGVPENCKPWSVRV 1333
            LCVTG+PENCKPWSVRV
Sbjct: 1320 LCVTGIPENCKPWSVRV 1336
>ref|XP_862684.1| PREDICTED: similar to Xanthine dehydrogenase/oxidase isoform 8 [Canis
            familiaris]
          Length = 1345

 Score = 2508 bits (6501), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1208/1346 (89%), Positives = 1274/1346 (94%), Gaps = 14/1346 (1%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKL LSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
             QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTK+RLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   FQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG  +NPNCC
Sbjct: 121  VMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSRDNPNCC 180

Query: 181  MNQKKDHSVS-------------LSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQL 227
            +NQKKD SVS             LSPSLF PEEF PLDPTQEPIFPPELLRLKD P+KQL
Sbjct: 181  LNQKKDCSVSGISPSCSLFQRVILSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPQKQL 240

Query: 228  RFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPEL 287
             F+GERVTWIQASTLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMIVCPAWIPEL
Sbjct: 241  CFKGERVTWIQASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPEL 300

Query: 288  NSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVAS 347
            N+VEHG +GISFGAACPLSIVEKTL DAV KLPA KTEVF+GVLEQLRWFAGKQVKSVAS
Sbjct: 301  NAVEHGLEGISFGAACPLSIVEKTLHDAVNKLPAYKTEVFKGVLEQLRWFAGKQVKSVAS 360

Query: 348  VGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSI 407
            +GGNII ASPISDLNPVFMAS AKLT+VSRG +RTV+MDHTFFPGYRKTLL+PEEILLSI
Sbjct: 361  IGGNIINASPISDLNPVFMASEAKLTIVSRGIKRTVRMDHTFFPGYRKTLLAPEEILLSI 420

Query: 408  EIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISAL 467
            EIPYSREGE+FSAFKQASRREDDIAKVTSGMRVLF PGT +V+ELALCYGGM +RTISAL
Sbjct: 421  EIPYSREGEFFSAFKQASRREDDIAKVTSGMRVLFHPGTAQVKELALCYGGMDDRTISAL 480

Query: 468  KTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKL 527
            KTT++Q+  LW E+LLQ+VCAGLAEEL L PDAPGGMVDFR TLTLSFFFKFYLTVLQKL
Sbjct: 481  KTTRKQVENLWNEDLLQNVCAGLAEELKLSPDAPGGMVDFRRTLTLSFFFKFYLTVLQKL 540

Query: 528  GQENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQA 587
             + NLE+KCGKLDPT+ASATLLFQKDPPA+VQLFQEVP+GQSEEDMVGRPLPHLAA MQA
Sbjct: 541  ERGNLENKCGKLDPTYASATLLFQKDPPANVQLFQEVPEGQSEEDMVGRPLPHLAAAMQA 600

Query: 588  SGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNIT 647
            SGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEA+KVPGFVCF+S +DVPGSN T
Sbjct: 601  SGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKT 660

Query: 648  GICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNS 707
            GI NDET+FA+D+VTC+GHIIGAVV DTPEH QRAAQGVKITYEELPAIITIEDAIKNNS
Sbjct: 661  GIFNDETIFAEDEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAIKNNS 720

Query: 708  FYGPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVST 767
            FYG ELKIEKG+L KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGE GE+ELF ST
Sbjct: 721  FYGSELKIEKGELTKGFSEADNVVSGEVYIGGQEHFYLETHCTIAVPKGEEGELELFAST 780

Query: 768  QNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCM 827
            QNTMKTQ+FVA MLGVP NRI+VRVKRMGGGFGGKETRST+VST VALAAYKTGRPVRCM
Sbjct: 781  QNTMKTQAFVANMLGVPINRILVRVKRMGGGFGGKETRSTLVSTVVALAAYKTGRPVRCM 840

Query: 828  LDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMD 887
            LDRDEDMLITGGRHPFLA+YKVGFMKTG VVALEV+H+SN GNT DLSQSIMERALFHMD
Sbjct: 841  LDRDEDMLITGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERALFHMD 900

Query: 888  NCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNL 947
            NCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAE WMSEVA+TCG+PAEEVRRKN+
Sbjct: 901  NCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNM 960

Query: 948  YKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFG 1007
            YKEGDLTHFNQKLEGFTL RCWEECLASSQYHARKSEVDKFN+EN WKKRGLCIIPTKFG
Sbjct: 961  YKEGDLTHFNQKLEGFTLSRCWEECLASSQYHARKSEVDKFNEENYWKKRGLCIIPTKFG 1020

Query: 1008 ISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISET 1067
            ISFT+ FLNQAGAL+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISET
Sbjct: 1021 ISFTLSFLNQAGALIHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISET 1080

Query: 1068 STNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVS 1127
            STNTVPNTSPTAASVSAD+NGQAVY AC+TILKRLEP+KKKNPSGSWEDWV  AY +TVS
Sbjct: 1081 STNTVPNTSPTAASVSADINGQAVYEACKTILKRLEPFKKKNPSGSWEDWVIDAYENTVS 1140

Query: 1128 LSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSL 1187
            LSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSL
Sbjct: 1141 LSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSL 1200

Query: 1188 NPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRD 1247
            NPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSL TRGPSTYKIPAFG+IP EFRVSLLRD
Sbjct: 1201 NPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRD 1260

Query: 1248 CPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIR 1307
            CPNKKAIYASKAVGEPPLFLAAS+FFAIKDA+RAARA+++    K LFRLDSPATPEKIR
Sbjct: 1261 CPNKKAIYASKAVGEPPLFLAASVFFAIKDAVRAARARNSDCKTK-LFRLDSPATPEKIR 1319

Query: 1308 NACVDKFTTLCVTGVPENCKPWSVRV 1333
            NACVD+FTTLCVTG+PENCKPWSVRV
Sbjct: 1320 NACVDEFTTLCVTGIPENCKPWSVRV 1345
>gb|EDM02851.1| rCG61833 [Rattus norvegicus]
          Length = 1331

 Score = 2497 bits (6471), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1207/1333 (90%), Positives = 1279/1333 (95%), Gaps = 2/1333 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLL YLRRKLGL GTKLGCGEGGCGACTVM+SKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQNKIVHFS NACLAPICSLHHVAVTTVEGIG+T+ +LHPVQERIA+SHGSQCGFCTPGI
Sbjct: 61   LQNKIVHFSVNACLAPICSLHHVAVTTVEGIGNTQ-KLHPVQERIARSHGSQCGFCTPGI 119

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG GNNPNCC
Sbjct: 120  VMSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCC 179

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQ KD +VSLSPSLF PE+F PLDPTQEPIFPPELLRLKDTP+K+LRFEGERVTWIQAS
Sbjct: 180  MNQTKDQTVSLSPSLFNPEDFKPLDPTQEPIFPPELLRLKDTPQKKLRFEGERVTWIQAS 239

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            T++ELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP+IVCPAWIPELNSV HGP+GISFG
Sbjct: 240  TMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIVCPAWIPELNSVVHGPEGISFG 299

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            A+CPLS+VE  L + +AKLP QKTEVFRGV+EQLRWFAGKQVKSVAS+GGNIITASPISD
Sbjct: 300  ASCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISD 359

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLTLVSRGTRRTV+MDHTFFPGYRKTLL PEEILLSIEIPYS+EGE+FSA
Sbjct: 360  LNPVFMASGAKLTLVSRGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSA 419

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVTSGMRVLFKPGT EVQEL+LC+GGMA+RTISALKTT +QLSK W E
Sbjct: 420  FKQASRREDDIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNE 479

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            ELLQ VCAGLAEELHL PDAPGGMV+FR TLTLSFFFKFYLTVLQKLG+ +LED CGKLD
Sbjct: 480  ELLQSVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEDMCGKLD 539

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PTFASATLLFQKDPPA+VQLFQEVPK QSEEDMVGRPLPHLAA+MQASGEAVYCDDIPRY
Sbjct: 540  PTFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQASGEAVYCDDIPRY 599

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENELSLRLVTSTRAHAKI SIDTSEAKKVPGFVCF++A+DVP SN TG+ NDETVFAKD+
Sbjct: 600  ENELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSNATGLFNDETVFAKDE 659

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVVADTPEH QRAA+GVKITYE+LPAIITI+DAI NNSFYG E+KIEKGDL
Sbjct: 660  VTCVGHIIGAVVADTPEHAQRAARGVKITYEDLPAIITIQDAINNNSFYGSEIKIEKGDL 719

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGE+YIGGQEHFYLET+CTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM
Sbjct: 720  KKGFSEADNVVSGELYIGGQEHFYLETNCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 779

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVP NRIVVRVKRMGGGFGGKETRSTVVSTAVALAA+KTGRPVRCMLDRDEDMLITGGR
Sbjct: 780  LGVPDNRIVVRVKRMGGGFGGKETRSTVVSTAVALAAHKTGRPVRCMLDRDEDMLITGGR 839

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLA+YKVGFMKTGTVVALEV HFSN GNT+DLS+SIMERALFHMDN YKIPNIRGTGR
Sbjct: 840  HPFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGR 899

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            +CKTNLPSNTAFRGFGGPQGMLIAE WMSEVA+TCG+PAEEVRRKN+YKEGDLTHFNQKL
Sbjct: 900  ICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKL 959

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTLPRCW+EC+ASSQY ARK EV+KFN+ENCWKKRGLCIIPTKFGISFT+PFLNQ GA
Sbjct: 960  EGFTLPRCWDECIASSQYLARKREVEKFNRENCWKKRGLCIIPTKFGISFTLPFLNQGGA 1019

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI+ISETSTNTVPNTSPTAA
Sbjct: 1020 LVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETSTNTVPNTSPTAA 1079

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            S SADLNGQAVY ACQTILKRLEP+KKK P+G WE WV  AY   VSLSATGFY+TPNLG
Sbjct: 1080 SASADLNGQAVYEACQTILKRLEPFKKKKPNGPWEAWVMDAYTSAVSLSATGFYKTPNLG 1139

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1140 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1199

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFT+EELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNK+AIYASKAV
Sbjct: 1200 VQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAV 1259

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLA+SIFFAIKDAIRAARAQH G+N K+LF+LDSPATPEKIRNACVD+FTTLCVT
Sbjct: 1260 GEPPLFLASSIFFAIKDAIRAARAQH-GDNAKQLFQLDSPATPEKIRNACVDQFTTLCVT 1318

Query: 1321 GVPENCKPWSVRV 1333
            GVPENCK WSVR+
Sbjct: 1319 GVPENCKSWSVRI 1331
>ref|XP_862658.1| PREDICTED: similar to Xanthine dehydrogenase/oxidase isoform 7 [Canis
            familiaris]
          Length = 1360

 Score = 2496 bits (6468), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1207/1361 (88%), Positives = 1273/1361 (93%), Gaps = 29/1361 (2%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKL LSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
             QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTK+RLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   FQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFAR--------------- 165
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+               
Sbjct: 121  VMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFAKTGWPAGSSSCCGYLA 180

Query: 166  ------------DGGCCGGDGNNPNCCMNQKKDHS-VSLSPSLFKPEEFTPLDPTQEPIF 212
                        DGGCCGG  +NPNCC+NQKKD S V LSPSLF PEEF PLDPTQEPIF
Sbjct: 181  RAFCHSHSEGSLDGGCCGGSRDNPNCCLNQKKDCSRVILSPSLFNPEEFMPLDPTQEPIF 240

Query: 213  PPELLRLKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKN 272
            PPELLRLKD P+KQL F+GERVTWIQASTLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN
Sbjct: 241  PPELLRLKDVPQKQLCFKGERVTWIQASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKN 300

Query: 273  MLFPMIVCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLE 332
             LFPMIVCPAWIPELN+VEHG +GISFGAACPLSIVEKTL DAV KLPA KTEVF+GVLE
Sbjct: 301  RLFPMIVCPAWIPELNAVEHGLEGISFGAACPLSIVEKTLHDAVNKLPAYKTEVFKGVLE 360

Query: 333  QLRWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPG 392
            QLRWFAGKQVKSVAS+GGNII ASPISDLNPVFMAS AKLT+VSRG +RTV+MDHTFFPG
Sbjct: 361  QLRWFAGKQVKSVASIGGNIINASPISDLNPVFMASEAKLTIVSRGIKRTVRMDHTFFPG 420

Query: 393  YRKTLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQEL 452
            YRKTLL+PEEILLSIEIPYSREGE+FSAFKQASRREDDIAKVTSGMRVLF PGT +V+EL
Sbjct: 421  YRKTLLAPEEILLSIEIPYSREGEFFSAFKQASRREDDIAKVTSGMRVLFHPGTAQVKEL 480

Query: 453  ALCYGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLT 512
            ALCYGGM +RTISALKTT++Q+  LW E+LLQ+VCAGLAEEL L PDAPGGMVDFR TLT
Sbjct: 481  ALCYGGMDDRTISALKTTRKQVENLWNEDLLQNVCAGLAEELKLSPDAPGGMVDFRRTLT 540

Query: 513  LSFFFKFYLTVLQKLGQENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEED 572
            LSFFFKFYLTVLQKL + NLE+KCGKLDPT+ASATLLFQKDPPA+VQLFQEVP+GQSEED
Sbjct: 541  LSFFFKFYLTVLQKLERGNLENKCGKLDPTYASATLLFQKDPPANVQLFQEVPEGQSEED 600

Query: 573  MVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGF 632
            MVGRPLPHLAA MQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEA+KVPGF
Sbjct: 601  MVGRPLPHLAAAMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGF 660

Query: 633  VCFISADDVPGSNITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEE 692
            VCF+S +DVPGSN TGI NDET+FA+D+VTC+GHIIGAVV DTPEH QRAAQGVKITYEE
Sbjct: 661  VCFLSFNDVPGSNKTGIFNDETIFAEDEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEE 720

Query: 693  LPAIITIEDAIKNNSFYGPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIA 752
            LPAIITIEDAIKNNSFYG ELKIEKG+L KGFSEADNVVSGE+YIGGQEHFYLETHCTIA
Sbjct: 721  LPAIITIEDAIKNNSFYGSELKIEKGELTKGFSEADNVVSGEVYIGGQEHFYLETHCTIA 780

Query: 753  VPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTA 812
            VPKGE GE+ELF STQNTMKTQ+FVA MLGVP NRI+VRVKRMGGGFGGKETRST+VST 
Sbjct: 781  VPKGEEGELELFASTQNTMKTQAFVANMLGVPINRILVRVKRMGGGFGGKETRSTLVSTV 840

Query: 813  VALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQ 872
            VALAAYKTGRPVRCMLDRDEDMLITGGRHPFLA+YKVGFMKTG VVALEV+H+SN GNT 
Sbjct: 841  VALAAYKTGRPVRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTL 900

Query: 873  DLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVA 932
            DLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAE WMSEVA
Sbjct: 901  DLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVA 960

Query: 933  VTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKEN 992
            +TCG+PAEEVRRKN+YKEGDLTHFNQKLEGFTL RCWEECLASSQYHARKSEVDKFN+EN
Sbjct: 961  MTCGLPAEEVRRKNMYKEGDLTHFNQKLEGFTLSRCWEECLASSQYHARKSEVDKFNEEN 1020

Query: 993  CWKKRGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVAS 1052
             WKKRGLCIIPTKFGISFT+ FLNQAGAL+HVYTDGSVLLTHGGTEMGQGLHTKMVQVAS
Sbjct: 1021 YWKKRGLCIIPTKFGISFTLSFLNQAGALIHVYTDGSVLLTHGGTEMGQGLHTKMVQVAS 1080

Query: 1053 RALKIPTSKIYISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSG 1112
            RALKIPTSKIYISETSTNTVPNTSPTAASVSAD+NGQAVY AC+TILKRLEP+KKKNPSG
Sbjct: 1081 RALKIPTSKIYISETSTNTVPNTSPTAASVSADINGQAVYEACKTILKRLEPFKKKNPSG 1140

Query: 1113 SWEDWVTAAYMDTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDH 1172
            SWEDWV  AY +TVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDH
Sbjct: 1141 SWEDWVIDAYENTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDH 1200

Query: 1173 KNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPA 1232
            KNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSL TRGPSTYKIPA
Sbjct: 1201 KNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPA 1260

Query: 1233 FGSIPIEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVK 1292
            FG+IP EFRVSLLRDCPNKKAIYASKAVGEPPLFLAAS+FFAIKDA+RAARA+++    K
Sbjct: 1261 FGNIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASVFFAIKDAVRAARARNSDCKTK 1320

Query: 1293 ELFRLDSPATPEKIRNACVDKFTTLCVTGVPENCKPWSVRV 1333
             LFRLDSPATPEKIRNACVD+FTTLCVTG+PENCKPWSVRV
Sbjct: 1321 -LFRLDSPATPEKIRNACVDEFTTLCVTGIPENCKPWSVRV 1360
>ref|NP_058850.1| xanthine dehydrogenase [Rattus norvegicus]
 sp|P22985|XDH_RAT Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase
            (XD); Xanthine oxidase (XO) (Xanthine oxidoreductase)]
 gb|AAA42349.1| xanthine dehydrogenase
          Length = 1331

 Score = 2491 bits (6456), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1204/1333 (90%), Positives = 1277/1333 (95%), Gaps = 2/1333 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLL YLRRKLGL GTKLGCGEGGCGACTVM+SKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQNKIVHFS NACLAPICSLHHVAVTTVEGIG+T+ +LHPVQERIA+SHGSQCGFCTPGI
Sbjct: 61   LQNKIVHFSVNACLAPICSLHHVAVTTVEGIGNTQ-KLHPVQERIARSHGSQCGFCTPGI 119

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG GNNPNCC
Sbjct: 120  VMSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCC 179

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQ KD +VSLSPSLF PE+F PLDPTQEPIFPPELLRLKDTP+K+LRFEGERVTWIQAS
Sbjct: 180  MNQTKDQTVSLSPSLFNPEDFKPLDPTQEPIFPPELLRLKDTPQKKLRFEGERVTWIQAS 239

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            T++ELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP+IVCPAWIPELNSV HGP+GISFG
Sbjct: 240  TMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIVCPAWIPELNSVVHGPEGISFG 299

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            A+CPLS+VE  L + +AKLP QKTEVFRGV+EQLRWFAGKQVKSVAS+GGNIITASPISD
Sbjct: 300  ASCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISD 359

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLTLVSRGTRRTV+MDHTFFPGYRKTLL PEEILLSIEIPYS+EGE+FSA
Sbjct: 360  LNPVFMASGAKLTLVSRGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSA 419

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVTSGMRVLFKPGT EVQEL+LC+GGMA+RTISALKTT +QLSK W E
Sbjct: 420  FKQASRREDDIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNE 479

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            ELLQ VCAGLAEEL L PDAPGGMV+FR TLTLSFFFKFYLTVLQKLG+ +LED CGKLD
Sbjct: 480  ELLQSVCAGLAEELQLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEDMCGKLD 539

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PTFASATLLFQKDPPA+VQLFQEVPK QSEEDMVGRPLPHLAA+MQASGEAVYCDDIPRY
Sbjct: 540  PTFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQASGEAVYCDDIPRY 599

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENELSLRLVTSTRAHAKI SIDTSEAKKVPGFVCF++A+DVP SN TG+ NDETVFAKD+
Sbjct: 600  ENELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSNATGLFNDETVFAKDE 659

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVVADTPEH QRAA+GVKITYE+LPAIITI+DAI NNSFYG E+KIEKGDL
Sbjct: 660  VTCVGHIIGAVVADTPEHAQRAARGVKITYEDLPAIITIQDAINNNSFYGSEIKIEKGDL 719

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGE+YIGGQEHFYLET+CTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM
Sbjct: 720  KKGFSEADNVVSGELYIGGQEHFYLETNCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 779

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVP NRIVVRVKRMGGGFGGKETRSTVVSTA+ALAA+KTGRPVRCMLDRDEDMLITGGR
Sbjct: 780  LGVPDNRIVVRVKRMGGGFGGKETRSTVVSTALALAAHKTGRPVRCMLDRDEDMLITGGR 839

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLA+YKVGFMKTGTVVALEV HFSN GNT+DLS+SIMERALFHMDN YKIPNIRGTGR
Sbjct: 840  HPFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGR 899

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            +CKTNLPSNTAFRGFGGPQGMLIAE WMSEVA+TCG+PAEEVRRKN+YKEGDLTHFNQKL
Sbjct: 900  ICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKL 959

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTLPRCW+EC+ASSQY ARK EV+KFN+ENCWKKRGLCIIPTKFGISFT+PFLNQ GA
Sbjct: 960  EGFTLPRCWDECIASSQYLARKREVEKFNRENCWKKRGLCIIPTKFGISFTLPFLNQGGA 1019

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI+ISETSTNTVPNTSPTAA
Sbjct: 1020 LVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETSTNTVPNTSPTAA 1079

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            S SADLNGQ VY ACQTILKRLEP+KKK P+G WE WV  AY   VSLSATGFY+TPNLG
Sbjct: 1080 SASADLNGQGVYEACQTILKRLEPFKKKKPTGPWEAWVMDAYTSAVSLSATGFYKTPNLG 1139

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1140 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1199

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFT+EELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNK+AIYASKAV
Sbjct: 1200 VQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAV 1259

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLA+SIFFAIKDAIRAARAQH G+N K+LF+LDSPATPEKIRNACVD+FTTLCVT
Sbjct: 1260 GEPPLFLASSIFFAIKDAIRAARAQH-GDNAKQLFQLDSPATPEKIRNACVDQFTTLCVT 1318

Query: 1321 GVPENCKPWSVRV 1333
            GVPENCK WSVR+
Sbjct: 1319 GVPENCKSWSVRI 1331
>ref|XP_862565.1| PREDICTED: similar to Xanthine dehydrogenase/oxidase isoform 3 [Canis
            familiaris]
          Length = 1339

 Score = 2491 bits (6456), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1204/1340 (89%), Positives = 1270/1340 (94%), Gaps = 8/1340 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKL LSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
             QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTK+RLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   FQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFAR---DGGCCGGDGNNP 177
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+   DG   GG  +NP
Sbjct: 121  VMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFAKESEDGLLEGGTLDNP 180

Query: 178  NCCMNQKKDHS----VSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGER 233
            NCC+NQKKD S    V LSPSLF PEEF PLDPTQEPIFPPELLRLKD P+KQL F+GER
Sbjct: 181  NCCLNQKKDCSGGARVILSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPQKQLCFKGER 240

Query: 234  VTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHG 293
            VTWIQASTLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMIVCPAWIPELN+VEHG
Sbjct: 241  VTWIQASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHG 300

Query: 294  PDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNII 353
             +GISFGAACPLSIVEKTL DAV KLPA KTEVF+GVLEQLRWFAGKQVKSVAS+GGNII
Sbjct: 301  LEGISFGAACPLSIVEKTLHDAVNKLPAYKTEVFKGVLEQLRWFAGKQVKSVASIGGNII 360

Query: 354  TASPISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSR 413
             ASPISDLNPVFMAS AKLT+VSRG +RTV+MDHTFFPGYRKTLL+PEEILLSIEIPYSR
Sbjct: 361  NASPISDLNPVFMASEAKLTIVSRGIKRTVRMDHTFFPGYRKTLLAPEEILLSIEIPYSR 420

Query: 414  EGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQ 473
            EGE+FSAFKQASRREDDIAKVTSGMRVLF PGT +V+ELALCYGGM +RTISALKTT++Q
Sbjct: 421  EGEFFSAFKQASRREDDIAKVTSGMRVLFHPGTAQVKELALCYGGMDDRTISALKTTRKQ 480

Query: 474  LSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLE 533
            +  LW E+LLQ+VCAGLAEEL L PDAPGGMVDFR TLTLSFFFKFYLTVLQKL + NLE
Sbjct: 481  VENLWNEDLLQNVCAGLAEELKLSPDAPGGMVDFRRTLTLSFFFKFYLTVLQKLERGNLE 540

Query: 534  DKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVY 593
            +KCGKLDPT+ASATLLFQKDPPA+VQLFQEVP+GQSEEDMVGRPLPHLAA MQASGEAVY
Sbjct: 541  NKCGKLDPTYASATLLFQKDPPANVQLFQEVPEGQSEEDMVGRPLPHLAAAMQASGEAVY 600

Query: 594  CDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDE 653
            CDDIPRYENELSLRLVTSTRAHAKIKSIDTSEA+KVPGFVCF+S +DVPGSN TGI NDE
Sbjct: 601  CDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKTGIFNDE 660

Query: 654  TVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPEL 713
            T+FA+D+VTC+GHIIGAVV DTPEH QRAAQGVKITYEELPAIITIEDAIKNNSFYG EL
Sbjct: 661  TIFAEDEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAIKNNSFYGSEL 720

Query: 714  KIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKT 773
            KIEKG+L KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGE GE+ELF STQNTMKT
Sbjct: 721  KIEKGELTKGFSEADNVVSGEVYIGGQEHFYLETHCTIAVPKGEEGELELFASTQNTMKT 780

Query: 774  QSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDED 833
            Q+FVA MLGVP NRI+VRVKRMGGGFGGKETRST+VST VALAAYKTGRPVRCMLDRDED
Sbjct: 781  QAFVANMLGVPINRILVRVKRMGGGFGGKETRSTLVSTVVALAAYKTGRPVRCMLDRDED 840

Query: 834  MLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIP 893
            MLITGGRHPFLA+YKVGFMKTG VVALEV+H+SN GNT DLSQSIMERALFHMDNCYKIP
Sbjct: 841  MLITGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERALFHMDNCYKIP 900

Query: 894  NIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDL 953
            NIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAE WMSEVA+TCG+PAEEVRRKN+YKEGDL
Sbjct: 901  NIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGDL 960

Query: 954  THFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVP 1013
            THFNQKLEGFTL RCWEECLASSQYHARKSEVDKFN+EN WKKRGLCIIPTKFGISFT+ 
Sbjct: 961  THFNQKLEGFTLSRCWEECLASSQYHARKSEVDKFNEENYWKKRGLCIIPTKFGISFTLS 1020

Query: 1014 FLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVP 1073
            FLNQAGAL+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVP
Sbjct: 1021 FLNQAGALIHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVP 1080

Query: 1074 NTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGF 1133
            NTSPTAASVSAD+NGQAVY AC+TILKRLEP+KKKNPSGSWEDWV  AY +TVSLSATGF
Sbjct: 1081 NTSPTAASVSADINGQAVYEACKTILKRLEPFKKKNPSGSWEDWVIDAYENTVSLSATGF 1140

Query: 1134 YRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDI 1193
            YRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDI
Sbjct: 1141 YRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDI 1200

Query: 1194 GQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKA 1253
            GQVEGAFVQGLGLFTLEELHYSPEGSL TRGPSTYKIPAFG+IP EFRVSLLRDCPNKKA
Sbjct: 1201 GQVEGAFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRDCPNKKA 1260

Query: 1254 IYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDK 1313
            IYASKAVGEPPLFLAAS+FFAIKDA+RAARA+++    K LFRLDSPATPEKIRNACVD+
Sbjct: 1261 IYASKAVGEPPLFLAASVFFAIKDAVRAARARNSDCKTK-LFRLDSPATPEKIRNACVDE 1319

Query: 1314 FTTLCVTGVPENCKPWSVRV 1333
            FTTLCVTG+PENCKPWSVRV
Sbjct: 1320 FTTLCVTGIPENCKPWSVRV 1339
>gb|ABL96618.1| xanthine oxidoreductase [Capra hircus]
          Length = 1333

 Score = 2491 bits (6456), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1203/1333 (90%), Positives = 1273/1333 (95%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKLGL GTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLRGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQ+KI+HFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQDKIIHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIE+AFQGNLCRCTGYRPILQGFRTFA++GGCCGG+GNN NCC
Sbjct: 121  VMSMYTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRTFAKNGGCCGGNGNNANCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            M+QKKDH V+LSPSLF PEEF PLDPTQEPIFPPELLRLKD P KQLRFEGERVTWIQ+S
Sbjct: 181  MDQKKDHRVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDIPPKQLRFEGERVTWIQSS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN  FP+I+CPAW PELNSVEHGP+GISFG
Sbjct: 241  TLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNQPFPVIICPAWTPELNSVEHGPEGISFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            AACPLS VEKTL++AVAKLP QKTEVFRGVLEQLRWFAGKQVKSVAS+GGNIITASPISD
Sbjct: 301  AACPLSSVEKTLLEAVAKLPTQKTEVFRGVLEQLRWFAGKQVKSVASIGGNIITASPISD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASG KLT++SRGTRRT+ MDHTFFP YRKTLL PEEILLSIEIPYSRE E+FSA
Sbjct: 361  LNPVFMASGTKLTIMSRGTRRTIPMDHTFFPSYRKTLLGPEEILLSIEIPYSREDEFFSA 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVT GMRVLF+PG+T+V+ELALCYGGMA+RTISALKTT+RQLSK W E
Sbjct: 421  FKQASRREDDIAKVTCGMRVLFQPGSTQVKELALCYGGMADRTISALKTTRRQLSKFWNE 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            +LLQDVCAGLAEEL LPPDAPGGMV+FR TLTLSFFFKFYLTVL+KLG+E+ EDKCGKLD
Sbjct: 481  KLLQDVCAGLAEELSLPPDAPGGMVEFRRTLTLSFFFKFYLTVLKKLGKEDSEDKCGKLD 540

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PT+ SATLLFQKDPPA++QLFQEVPKGQS+ED VGRPLPHLAA MQASGEAVYCDDIPRY
Sbjct: 541  PTYTSATLLFQKDPPANIQLFQEVPKGQSKEDTVGRPLPHLAAAMQASGEAVYCDDIPRY 600

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            E+EL LRLVTSTRAHAKIKSID SEA+KVPGFVCF+SADD+PGSN TG+ NDETVFAKDK
Sbjct: 601  ESELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKDK 660

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVVADTPEH QRAA GVK+TYE+LPAIITIEDAIKNNSFYG ELKIEKGDL
Sbjct: 661  VTCVGHIIGAVVADTPEHAQRAAHGVKVTYEDLPAIITIEDAIKNNSFYGSELKIEKGDL 720

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGEAGEMELF STQN MKTQSFVAKM
Sbjct: 721  KKGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFASTQNPMKTQSFVAKM 780

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVP NRI+VRVKRMGGGFGGKETRST+V+ AVALAAYKTG PVRCMLDRDEDMLITGGR
Sbjct: 781  LGVPVNRILVRVKRMGGGFGGKETRSTLVTVAVALAAYKTGHPVRCMLDRDEDMLITGGR 840

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTG +VALEVDH+SN GN+QDLS  IMERALFHMDNCYKIPNIRGTGR
Sbjct: 841  HPFLARYKVGFMKTGKIVALEVDHYSNAGNSQDLSHGIMERALFHMDNCYKIPNIRGTGR 900

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            LCKTNLPSNTAFRGFGGPQ + IAE WMSEVAVTCG+PAEEVRRKNLYKEGDLTHFNQ+L
Sbjct: 901  LCKTNLPSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRRKNLYKEGDLTHFNQRL 960

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGF++PRCW+ECL SSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFT+PFLNQAGA
Sbjct: 961  EGFSVPRCWDECLKSSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTIPFLNQAGA 1020

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVL++HGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPN+SPTAA
Sbjct: 1021 LIHVYTDGSVLVSHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNSSPTAA 1080

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVS D+ GQA+Y ACQTILKRLEP+K+KNP GSWEDWV AAY D VSLSATGFYRTPNLG
Sbjct: 1081 SVSTDIYGQAIYEACQTILKRLEPFKRKNPDGSWEDWVMAAYQDRVSLSATGFYRTPNLG 1140

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGN FHYF+YGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1141 YSFETNSGNAFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIP EF VSLLRDCPNKKAIYASKAV
Sbjct: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPTEFGVSLLRDCPNKKAIYASKAV 1260

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFL ASIFFAIKDAIRAARAQHT N +KELFRLDSPATPEKIRNACVDKFTTLCVT
Sbjct: 1261 GEPPLFLGASIFFAIKDAIRAARAQHTDNKIKELFRLDSPATPEKIRNACVDKFTTLCVT 1320

Query: 1321 GVPENCKPWSVRV 1333
             VPENCKPWS+RV
Sbjct: 1321 CVPENCKPWSLRV 1333
>ref|XP_001501696.1| PREDICTED: similar to xanthine dehydrogenase/oxidase [Equus caballus]
          Length = 1333

 Score = 2488 bits (6448), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1182/1333 (88%), Positives = 1261/1333 (94%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVM SKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMFSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQNKIVHF ANACLAPICSLHHVAVTTVEGIGST+TRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQNKIVHFPANACLAPICSLHHVAVTTVEGIGSTRTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPTMEEIE+A QGNLCRCTGYRPILQGFRTFARDGGCCGG GN+PNCC
Sbjct: 121  VMSMYTLLRNQPEPTMEEIEDALQGNLCRCTGYRPILQGFRTFARDGGCCGGKGNDPNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQKKDH+V+LSPSLF PEEF PLDPTQEPIFPPELLRLKD P+KQL FEGERVTWIQAS
Sbjct: 181  MNQKKDHTVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDAPQKQLHFEGERVTWIQAS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TLKELLDLKAQHP+A LVVGN EIGIEMKFKN LFP+IVCPAWIPELNSVEHG +GISFG
Sbjct: 241  TLKELLDLKAQHPEATLVVGNMEIGIEMKFKNKLFPLIVCPAWIPELNSVEHGEEGISFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            A+CPLS VEKTL+DAVA+LP  KTEVFRGVLEQLRWF+GKQ+KSVAS+GGN+ITASPISD
Sbjct: 301  ASCPLSCVEKTLLDAVAQLPTHKTEVFRGVLEQLRWFSGKQLKSVASIGGNVITASPISD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLT+VSRGTRRT++MDHTFFPGYRKTLL PEEILL+IEIPYSREGE+FS+
Sbjct: 361  LNPVFMASGAKLTMVSRGTRRTIRMDHTFFPGYRKTLLGPEEILLAIEIPYSREGEFFSS 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQ+S RED +AKVTSGMRVLFKPGTT+++EL LCYGGMA+RTISALKTT++QLSK W E
Sbjct: 421  FKQSSGREDYVAKVTSGMRVLFKPGTTQIEELVLCYGGMADRTISALKTTRKQLSKFWNE 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
             LLQDVCAGLAEEL L PDAPGGM++FR TLTLSFFFKFYLTVLQKLG+ + EDKCGKLD
Sbjct: 481  GLLQDVCAGLAEELQLAPDAPGGMIEFRRTLTLSFFFKFYLTVLQKLGKVDSEDKCGKLD 540

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PTFASATLLFQKDPP +VQLFQEVPKGQSEEDMVGRPLPHL A MQA GEA+YCDDIPRY
Sbjct: 541  PTFASATLLFQKDPPTNVQLFQEVPKGQSEEDMVGRPLPHLGASMQACGEAMYCDDIPRY 600

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            +NELSLRLVTSTRAHAKIKSIDTSEA+KVPGFVCF+SADDV GSN TG  NDETVFA D+
Sbjct: 601  QNELSLRLVTSTRAHAKIKSIDTSEAQKVPGFVCFLSADDVSGSNKTGFFNDETVFANDE 660

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVV DTPEH QRAAQ VKITYE+LPAIITIEDAIK+NSFYG ELKIEKGDL
Sbjct: 661  VTCVGHIIGAVVTDTPEHAQRAAQAVKITYEDLPAIITIEDAIKHNSFYGSELKIEKGDL 720

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            +KGF+EADN+VSGE YIGGQEHFYLETHC IAVPKGEAGEMELFVSTQNT KTQ+FVAK+
Sbjct: 721  QKGFAEADNIVSGEFYIGGQEHFYLETHCAIAVPKGEAGEMELFVSTQNTTKTQAFVAKV 780

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVPANRI++RVKR+GGGFGGKE RST+VSTAVA+ AYKTG PVRCMLDRDEDMLITGGR
Sbjct: 781  LGVPANRILIRVKRLGGGFGGKEIRSTLVSTAVAVGAYKTGCPVRCMLDRDEDMLITGGR 840

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTG +VALEVDH+SN GNT DLS++IM++ L HMDN YKIPNIRGTG 
Sbjct: 841  HPFLARYKVGFMKTGRIVALEVDHYSNAGNTLDLSEAIMQQTLLHMDNGYKIPNIRGTGW 900

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            LCKTNLPSNTAFRGFG PQGMLIAE WMSE+AVTCG+PAEEVRRKN+YKEGDLTHFNQKL
Sbjct: 901  LCKTNLPSNTAFRGFGRPQGMLIAEHWMSEIAVTCGLPAEEVRRKNMYKEGDLTHFNQKL 960

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTL RCW+ECLASSQYHARKSE+DKFNKENCWKKRGLCI+PTKFG+SFTV FLNQAGA
Sbjct: 961  EGFTLTRCWDECLASSQYHARKSEIDKFNKENCWKKRGLCIVPTKFGVSFTVHFLNQAGA 1020

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA
Sbjct: 1021 LIHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVS DLNGQAVY ACQTILKRLEP+K+KNPSGSWEDWV AAY D VSLSATGFY+ P++G
Sbjct: 1081 SVSTDLNGQAVYEACQTILKRLEPFKRKNPSGSWEDWVIAAYQDAVSLSATGFYKAPDVG 1140

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPF+YFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1141 YSFETNSGNPFNYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFTLEEL YSPEGSL+TRGPSTYKIP F SIPIEFRVSLLRD PNKKAIYASKAV
Sbjct: 1201 VQGLGLFTLEELQYSPEGSLYTRGPSTYKIPTFDSIPIEFRVSLLRDSPNKKAIYASKAV 1260

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLAAS+FFAIKDAIRAARAQH   ++KELFRLDSPAT EKIRNACVDKFTTLCVT
Sbjct: 1261 GEPPLFLAASVFFAIKDAIRAARAQHKDYDMKELFRLDSPATQEKIRNACVDKFTTLCVT 1320

Query: 1321 GVPENCKPWSVRV 1333
            GVPENCK WS+RV
Sbjct: 1321 GVPENCKAWSLRV 1333
>pdb|2E3T|A Chain A, Crystal Structure Of Rat Xanthine Oxidoreductase Mutant
            (W335a And F336l)
 pdb|2E3T|B Chain B, Crystal Structure Of Rat Xanthine Oxidoreductase Mutant
            (W335a And F336l)
          Length = 1331

 Score = 2482 bits (6434), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1202/1333 (90%), Positives = 1275/1333 (95%), Gaps = 2/1333 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLL YLRRKLGL GTKLGCGEGGCGACTVM+SKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQNKIVHFS NACLAPICSLHHVAVTTVEGIG+T+ +LHPVQERIA+SHGSQCGFCTPGI
Sbjct: 61   LQNKIVHFSVNACLAPICSLHHVAVTTVEGIGNTQ-KLHPVQERIARSHGSQCGFCTPGI 119

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG GNNPNCC
Sbjct: 120  VMSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCC 179

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQ KD +VSLSPSLF PE+F PLDPTQEPIFPPELLRLKDTP+K+LRFEGERVTWIQAS
Sbjct: 180  MNQTKDQTVSLSPSLFNPEDFKPLDPTQEPIFPPELLRLKDTPQKKLRFEGERVTWIQAS 239

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            T++ELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP+IVCPAWIPELNSV HGP+GISFG
Sbjct: 240  TMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIVCPAWIPELNSVVHGPEGISFG 299

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            A+CPLS+VE  L + +AKLP QKTEVFRGV+EQLR  AGKQVKSVAS+GGNIITASPISD
Sbjct: 300  ASCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRALAGKQVKSVASIGGNIITASPISD 359

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLTLVSRGTRRTV+MDHTFFPGYRKTLL PEEILLSIEIPYS+EGE+FSA
Sbjct: 360  LNPVFMASGAKLTLVSRGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSA 419

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVTSGMRVLFKPGT EVQEL+LC+GGMA+RTISALKTT +QLSK W E
Sbjct: 420  FKQASRREDDIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNE 479

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            ELLQ VCAGLAEEL L PDAPGGMV+FR TLTLSFFFKFYLTVLQKLG+ +LED CGKLD
Sbjct: 480  ELLQSVCAGLAEELQLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEDMCGKLD 539

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PTFASATLLFQKDPPA+VQLFQEVPK QSEEDMVGRPLPHLAA+MQASGEAVYCDDIPRY
Sbjct: 540  PTFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQASGEAVYCDDIPRY 599

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENELSLRLVTSTRAHAKI SIDTSEAKKVPGFVCF++A+DVP SN TG+ NDETVFAKD+
Sbjct: 600  ENELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSNATGLFNDETVFAKDE 659

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVVADTPEH QRAA+GVKITYE+LPAIITI+DAI NNSFYG E+KIEKGDL
Sbjct: 660  VTCVGHIIGAVVADTPEHAQRAARGVKITYEDLPAIITIQDAINNNSFYGSEIKIEKGDL 719

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGE+YIGGQEHFYLET+CTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM
Sbjct: 720  KKGFSEADNVVSGELYIGGQEHFYLETNCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 779

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVP NRIVVRVKRMGGGFGGKETRSTVVSTA+ALAA+KTGRPVRCMLDRDEDMLITGGR
Sbjct: 780  LGVPDNRIVVRVKRMGGGFGGKETRSTVVSTALALAAHKTGRPVRCMLDRDEDMLITGGR 839

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLA+YKVGFMKTGTVVALEV HFSN GNT+DLS+SIMERALFHMDN YKIPNIRGTGR
Sbjct: 840  HPFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGR 899

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            +CKTNLPSNTAFRGFGGPQGMLIAE WMSEVA+TCG+PAEEVRRKN+YKEGDLTHFNQKL
Sbjct: 900  ICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKL 959

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTLPRCW+EC+ASSQY ARK EV+KFN+ENCWKKRGLCIIPTKFGISFT+PFLNQ GA
Sbjct: 960  EGFTLPRCWDECIASSQYLARKREVEKFNRENCWKKRGLCIIPTKFGISFTLPFLNQGGA 1019

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI+ISETSTNTVPNTSPTAA
Sbjct: 1020 LVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETSTNTVPNTSPTAA 1079

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            S SADLNGQ VY ACQTILKRLEP+KKK P+G WE WV  AY   VSLSATGFY+TPNLG
Sbjct: 1080 SASADLNGQGVYEACQTILKRLEPFKKKKPTGPWEAWVMDAYTSAVSLSATGFYKTPNLG 1139

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1140 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1199

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFT+EELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNK+AIYASKAV
Sbjct: 1200 VQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAV 1259

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLA+SIFFAIKDAIRAARAQH G+N K+LF+LDSPATPEKIRNACVD+FTTLCVT
Sbjct: 1260 GEPPLFLASSIFFAIKDAIRAARAQH-GDNAKQLFQLDSPATPEKIRNACVDQFTTLCVT 1318

Query: 1321 GVPENCKPWSVRV 1333
            GVPENCK WSVR+
Sbjct: 1319 GVPENCKSWSVRI 1331
>pdb|1WYG|A Chain A, Crystal Structure Of A Rat Xanthine Dehydrogenase Triple
            Mutant (C535a, C992r And C1324s)
          Length = 1331

 Score = 2479 bits (6425), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1201/1333 (90%), Positives = 1274/1333 (95%), Gaps = 2/1333 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLL YLRRKLGL GTKLGCGEGGCGACTVM+SKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQNKIVHFS NACLAPICSLHHVAVTTVEGIG+T+ +LHPVQERIA+SHGSQCGFCTPGI
Sbjct: 61   LQNKIVHFSVNACLAPICSLHHVAVTTVEGIGNTQ-KLHPVQERIARSHGSQCGFCTPGI 119

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG GNNPNCC
Sbjct: 120  VMSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCC 179

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQ KD +VSLSPSLF PE+F PLDPTQEPIFPPELLRLKDTP+K+LRFEGERVTWIQAS
Sbjct: 180  MNQTKDQTVSLSPSLFNPEDFKPLDPTQEPIFPPELLRLKDTPQKKLRFEGERVTWIQAS 239

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            T++ELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP+IVCPAWIPELNSV HGP+GISFG
Sbjct: 240  TMEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIVCPAWIPELNSVVHGPEGISFG 299

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            A+CPLS+VE  L + +AKLP QKTEVFRGV+EQLRWFAGKQVKSVAS+GGNIITASPISD
Sbjct: 300  ASCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISD 359

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASGAKLTLVSRGTRRTV+MDHTFFPGYRKTLL PEEILLSIEIPYS+EGE+FSA
Sbjct: 360  LNPVFMASGAKLTLVSRGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSA 419

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVTSGMRVLFKPGT EVQEL+LC+GGMA+RTISALKTT +QLSK W E
Sbjct: 420  FKQASRREDDIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNE 479

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            ELLQ VCAGLAEEL L PDAPGGMV+FR TLTLSFFFKFYLTVLQKLG+ +LED  GKLD
Sbjct: 480  ELLQSVCAGLAEELQLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEDMAGKLD 539

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PTFASATLLFQKDPPA+VQLFQEVPK QSEEDMVGRPLPHLAA+MQASGEAVYCDDIPRY
Sbjct: 540  PTFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQASGEAVYCDDIPRY 599

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENELSLRLVTSTRAHAKI SIDTSEAKKVPGFVCF++A+DVP SN TG+ NDETVFAKD+
Sbjct: 600  ENELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSNATGLFNDETVFAKDE 659

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVVADTPEH QRAA+GVKITYE+LPAIITI+DAI NNSFYG E+KIEKGDL
Sbjct: 660  VTCVGHIIGAVVADTPEHAQRAARGVKITYEDLPAIITIQDAINNNSFYGSEIKIEKGDL 719

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGE+YIGGQEHFYLET+CTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM
Sbjct: 720  KKGFSEADNVVSGELYIGGQEHFYLETNCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 779

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVP NRIVVRVKRMGGGFGGKETRSTVVSTA+ALAA+KTGRPVRCMLDRDEDMLITGGR
Sbjct: 780  LGVPDNRIVVRVKRMGGGFGGKETRSTVVSTALALAAHKTGRPVRCMLDRDEDMLITGGR 839

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLA+YKVGFMKTGTVVALEV HFSN GNT+DLS+SIMERALFHMDN YKIPNIRGTGR
Sbjct: 840  HPFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGR 899

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            +CKTNLPSNTAFRGFGGPQGMLIAE WMSEVA+TCG+PAEEVRRKN+YKEGDLTHFNQKL
Sbjct: 900  ICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKL 959

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGFTLPRCW+EC+ASSQY ARK EV+KFN+EN WKKRGLCIIPTKFGISFT+PFLNQ GA
Sbjct: 960  EGFTLPRCWDECIASSQYLARKREVEKFNRENRWKKRGLCIIPTKFGISFTLPFLNQGGA 1019

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI+ISETSTNTVPNTSPTAA
Sbjct: 1020 LVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETSTNTVPNTSPTAA 1079

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            S SADLNGQ VY ACQTILKRLEP+KKK P+G WE WV  AY   VSLSATGFY+TPNLG
Sbjct: 1080 SASADLNGQGVYEACQTILKRLEPFKKKKPTGPWEAWVMDAYTSAVSLSATGFYKTPNLG 1139

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1140 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1199

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFT+EELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNK+AIYASKAV
Sbjct: 1200 VQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAV 1259

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFLA+SIFFAIKDAIRAARAQH G+N K+LF+LDSPATPEKIRNACVD+FTTLCVT
Sbjct: 1260 GEPPLFLASSIFFAIKDAIRAARAQH-GDNAKQLFQLDSPATPEKIRNACVDQFTTLCVT 1318

Query: 1321 GVPENCKPWSVRV 1333
            GVPEN K WSVR+
Sbjct: 1319 GVPENSKSWSVRI 1331
>gb|AAI41184.1| Xanthine dehydrogenase [Mus musculus]
          Length = 1335

 Score = 2478 bits (6422), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1191/1332 (89%), Positives = 1270/1332 (95%), Gaps = 1/1332 (0%)

Query: 2    TADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRL 61
            T D+LVFFVNG+KVVEKNADPETTLL YLRRKLGL GTKLGCGEGGCGACTVM+SKYDRL
Sbjct: 5    TVDELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRL 64

Query: 62   QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIV 121
            QNKIVHFS NACL PICSLHHVAVTTVEGIG+TK +LHPVQERIAKSHGSQCGFCTPGIV
Sbjct: 65   QNKIVHFSVNACLTPICSLHHVAVTTVEGIGNTK-KLHPVQERIAKSHGSQCGFCTPGIV 123

Query: 122  MSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCM 181
            MSMYTLLRN+PEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG GNNPNCCM
Sbjct: 124  MSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCM 183

Query: 182  NQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAST 241
            +Q KD +++ S SLF PE+F PLDPTQEPIFPPELLRLKDTPRK LRFEGERVTWIQ ST
Sbjct: 184  SQTKDQTIAPSSSLFNPEDFKPLDPTQEPIFPPELLRLKDTPRKTLRFEGERVTWIQVST 243

Query: 242  LKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGA 301
            ++ELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP+I+CPAWI EL SV HGP+GISFGA
Sbjct: 244  MEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGA 303

Query: 302  ACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDL 361
            ACPLS+VE  LVDA+A LP Q+TEVFRGV+EQLRWFAGKQVKSVAS+GGNIITASPISDL
Sbjct: 304  ACPLSLVESVLVDAIATLPEQRTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDL 363

Query: 362  NPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAF 421
            NPV MAS AKLTL SRGT+RTV MDHTFFPGYR+TLLSPEEIL+SI IPYSR+GE+FSAF
Sbjct: 364  NPVLMASRAKLTLASRGTKRTVWMDHTFFPGYRRTLLSPEEILVSIVIPYSRKGEFFSAF 423

Query: 422  KQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEE 481
            KQASRREDDIAKVTSGMRVLFKPGTTEVQEL+LC+GGMA+RT+SALKTT +QLSK W EE
Sbjct: 424  KQASRREDDIAKVTSGMRVLFKPGTTEVQELSLCFGGMADRTVSALKTTPKQLSKSWNEE 483

Query: 482  LLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDP 541
            LLQDVCAGLAEELHL PDAPGGMV+FR TLTLSFFFKFYLTVLQKLG+ +LE  CGKLDP
Sbjct: 484  LLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEGMCGKLDP 543

Query: 542  TFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYE 601
            TFASATLLFQKDPPA+VQLFQEVPKGQSEEDMVGRP+PHLAADMQASGEAVYCDDIPRYE
Sbjct: 544  TFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDDIPRYE 603

Query: 602  NELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKV 661
            NELSLRLVTSTRAHAKI SIDTSEAKKVPGFVCF++++DVPGSNITGI NDETVFAKD+V
Sbjct: 604  NELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTSEDVPGSNITGIFNDETVFAKDEV 663

Query: 662  TCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLK 721
            TCVGHIIGAVVADTPEH  RAA+GVKITYE+LPAIITI+DAIKNNSFYGPE+KIEKGDLK
Sbjct: 664  TCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSFYGPEVKIEKGDLK 723

Query: 722  KGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKML 781
            KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSF+AKML
Sbjct: 724  KGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKML 783

Query: 782  GVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 841
            GVP NRIVVRVKRMGGGFGGKETRST++STAVALAAYKTGRPVRCMLDRDEDMLITGGRH
Sbjct: 784  GVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 843

Query: 842  PFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRL 901
            PFLA+YKVGFMKTGT+VALEV HFSN GN++DLS+SIMERA+FHMDN YKIPNIRGTGR+
Sbjct: 844  PFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNIRGTGRI 903

Query: 902  CKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLE 961
            CKTNLPSNTAFRGFGGPQGMLIAE WMSEVAVTCG+PAEEVRRKN+YKEGDLTHFNQKLE
Sbjct: 904  CKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKLE 963

Query: 962  GFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGAL 1021
            GFTLPRCW+EC+ASSQY ARK EV+KFN+ENCWKKRGLCIIPTKFGISFT+ FLNQ GAL
Sbjct: 964  GFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGAL 1023

Query: 1022 LHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAAS 1081
            +HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI+I+ETSTNTVPNTSPTAAS
Sbjct: 1024 VHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAAS 1083

Query: 1082 VSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGY 1141
             SADLNGQA+Y ACQTILKRLEP+KKKNPSGSWE WV  AY   VSLSATGFY+TPNLGY
Sbjct: 1084 ASADLNGQAIYEACQTILKRLEPFKKKNPSGSWESWVMDAYTSAVSLSATGFYKTPNLGY 1143

Query: 1142 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1201
            SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV
Sbjct: 1144 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1203

Query: 1202 QGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVG 1261
            QGLGLFT+EELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNK+AIYASKAVG
Sbjct: 1204 QGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVG 1263

Query: 1262 EPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTG 1321
            EPPLFLA+SIFFAIKDAIRAARAQH  +N K+LF+LDSPATPEKIRNACVD+FTTLC TG
Sbjct: 1264 EPPLFLASSIFFAIKDAIRAARAQHGDSNAKQLFQLDSPATPEKIRNACVDQFTTLCATG 1323

Query: 1322 VPENCKPWSVRV 1333
             PENCK WSVR+
Sbjct: 1324 TPENCKSWSVRI 1335
>ref|NP_035853.2| xanthine dehydrogenase [Mus musculus]
          Length = 1335

 Score = 2477 bits (6419), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1190/1332 (89%), Positives = 1269/1332 (95%), Gaps = 1/1332 (0%)

Query: 2    TADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRL 61
            T D+LVFFVNG+KVVEKNADPETTLL YLRRKLGL GTKLGCGEGGCGACTVM+SKYDRL
Sbjct: 5    TVDELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRL 64

Query: 62   QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIV 121
            QNKIVHFS NACL PICSLHHVAVTTVEGIG+TK +LHPVQERIAKSHGSQCGFCTPGIV
Sbjct: 65   QNKIVHFSVNACLTPICSLHHVAVTTVEGIGNTK-KLHPVQERIAKSHGSQCGFCTPGIV 123

Query: 122  MSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCM 181
            MSMYTLLRN+PEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG GNNPNCCM
Sbjct: 124  MSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCM 183

Query: 182  NQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAST 241
            +Q KD +++ S SLF PE+F PLDPTQEPIFPPELLRLKDTPRK LRFEGERVTWIQ ST
Sbjct: 184  SQTKDQTIAPSSSLFNPEDFKPLDPTQEPIFPPELLRLKDTPRKTLRFEGERVTWIQVST 243

Query: 242  LKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGA 301
            ++ELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP+I+CPAWI EL SV HGP+GISFGA
Sbjct: 244  MEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGA 303

Query: 302  ACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDL 361
            ACPLS+VE  L DA+A LP Q+TEVFRGV+EQLRWFAGKQVKSVAS+GGNIITASPISDL
Sbjct: 304  ACPLSLVESVLADAIATLPEQRTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDL 363

Query: 362  NPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAF 421
            NPV MAS AKLTL SRGT+RTV MDHTFFPGYR+TLLSPEEIL+SI IPYSR+GE+FSAF
Sbjct: 364  NPVLMASRAKLTLASRGTKRTVWMDHTFFPGYRRTLLSPEEILVSIVIPYSRKGEFFSAF 423

Query: 422  KQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEE 481
            KQASRREDDIAKVTSGMRVLFKPGTTEVQEL+LC+GGMA+RT+SALKTT +QLSK W EE
Sbjct: 424  KQASRREDDIAKVTSGMRVLFKPGTTEVQELSLCFGGMADRTVSALKTTPKQLSKSWNEE 483

Query: 482  LLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDP 541
            LLQDVCAGLAEELHL PDAPGGMV+FR TLTLSFFFKFYLTVLQKLG+ +LE  CGKLDP
Sbjct: 484  LLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEGMCGKLDP 543

Query: 542  TFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYE 601
            TFASATLLFQKDPPA+VQLFQEVPKGQSEEDMVGRP+PHLAADMQASGEAVYCDDIPRYE
Sbjct: 544  TFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDDIPRYE 603

Query: 602  NELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKV 661
            NELSLRLVTSTRAHAKI SIDTSEAKKVPGFVCF++++DVPGSNITGI NDETVFAKD+V
Sbjct: 604  NELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSNITGIFNDETVFAKDEV 663

Query: 662  TCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLK 721
            TCVGHIIGAVVADTPEH  RAA+GVKITYE+LPAIITI+DAIKNNSFYGPE+KIEKGDLK
Sbjct: 664  TCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSFYGPEVKIEKGDLK 723

Query: 722  KGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKML 781
            KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSF+AKML
Sbjct: 724  KGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKML 783

Query: 782  GVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 841
            GVP NRIVVRVKRMGGGFGGKETRST++STAVALAAYKTGRPVRCMLDRDEDMLITGGRH
Sbjct: 784  GVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 843

Query: 842  PFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRL 901
            PFLA+YKVGFMKTGT+VALEV HFSN GN++DLS+SIMERA+FHMDN YKIPNIRGTGR+
Sbjct: 844  PFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNIRGTGRI 903

Query: 902  CKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLE 961
            CKTNLPSNTAFRGFGGPQGMLIAE WMSEVAVTCG+PAEEVRRKN+YKEGDLTHFNQKLE
Sbjct: 904  CKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKLE 963

Query: 962  GFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGAL 1021
            GFTLPRCW+EC+ASSQY ARK EV+KFN+ENCWKKRGLCIIPTKFGISFT+ FLNQ GAL
Sbjct: 964  GFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGAL 1023

Query: 1022 LHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAAS 1081
            +HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI+I+ETSTNTVPNTSPTAAS
Sbjct: 1024 VHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAAS 1083

Query: 1082 VSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGY 1141
             SADLNGQA+Y ACQTILKRLEP+KKKNPSGSWE WV  AY   VSLSATGFY+TPNLGY
Sbjct: 1084 ASADLNGQAIYEACQTILKRLEPFKKKNPSGSWESWVMDAYTSAVSLSATGFYKTPNLGY 1143

Query: 1142 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1201
            SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV
Sbjct: 1144 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1203

Query: 1202 QGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVG 1261
            QGLGLFT+EELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNK+AIYASKAVG
Sbjct: 1204 QGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVG 1263

Query: 1262 EPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTG 1321
            EPPLFLA+SIFFAIKDAIRAARAQH  +N K+LF+LDSPATPEKIRNACVD+FTTLC TG
Sbjct: 1264 EPPLFLASSIFFAIKDAIRAARAQHGDSNAKQLFQLDSPATPEKIRNACVDQFTTLCATG 1323

Query: 1322 VPENCKPWSVRV 1333
             PENCK WSVR+
Sbjct: 1324 TPENCKSWSVRI 1335
>sp|Q00519|XDH_MOUSE Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase
            (XD); Xanthine oxidase (XO) (Xanthine oxidoreductase)]
 emb|CAA52997.1| xanthine dehydrogenase [Mus musculus]
          Length = 1335

 Score = 2475 bits (6415), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1189/1332 (89%), Positives = 1269/1332 (95%), Gaps = 1/1332 (0%)

Query: 2    TADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRL 61
            T D+LVFFVNG+KVVEKNADPETTLL YLRRKLGL GTKLGCGEGGCGACTVM+SKYDRL
Sbjct: 5    TVDELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRL 64

Query: 62   QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIV 121
            QNKIVHFS NACL PICSLHHVAVTTVEGIG+TK +LHPVQERIAKSHGSQCGFCTPGIV
Sbjct: 65   QNKIVHFSVNACLTPICSLHHVAVTTVEGIGNTK-KLHPVQERIAKSHGSQCGFCTPGIV 123

Query: 122  MSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCM 181
            MSMYTLLRN+PEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG GNNPNCCM
Sbjct: 124  MSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCM 183

Query: 182  NQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAST 241
            +Q KD +++ S SLF PE+F PLDPTQEPIFPPELLRLKDTPRK LRFEGERVTWIQ ST
Sbjct: 184  SQTKDQTIAPSSSLFNPEDFKPLDPTQEPIFPPELLRLKDTPRKTLRFEGERVTWIQVST 243

Query: 242  LKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGA 301
            ++ELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP+I+CPAWI EL SV HGP+GISFGA
Sbjct: 244  MEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGA 303

Query: 302  ACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDL 361
            ACPLS+VE  L DA+A LP Q+TEVFRGV+EQLRWFAGKQVKSVAS+GGNIITASPISDL
Sbjct: 304  ACPLSLVESVLADAIATLPEQRTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDL 363

Query: 362  NPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAF 421
            NPV MAS AKLTL SRGT+RTV MDHTFFPGYR+TLLSPEEIL+SI IPYSR+GE+FSAF
Sbjct: 364  NPVLMASRAKLTLASRGTKRTVWMDHTFFPGYRRTLLSPEEILVSIVIPYSRKGEFFSAF 423

Query: 422  KQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEE 481
            KQASRREDDIAKVTSGMRVLFKPGTTEVQEL+LC+GGMA+RT+SALKTT +QLSK W EE
Sbjct: 424  KQASRREDDIAKVTSGMRVLFKPGTTEVQELSLCFGGMADRTVSALKTTPKQLSKSWNEE 483

Query: 482  LLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDP 541
            LLQDVCAGLAEELHL PDAPGGMV+FR TLTLSFFFKFYLTVLQKLG+ +LE  CGKLDP
Sbjct: 484  LLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEGMCGKLDP 543

Query: 542  TFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYE 601
            TFASATLLFQKDPPA+VQLFQEVPKGQSEEDMVGRP+PHLAADMQASGEAVYCDDIPRYE
Sbjct: 544  TFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDDIPRYE 603

Query: 602  NELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKV 661
            NELSLRLVTSTRAHAKI SIDTSEAKKVPGFVCF++++DVPGSNITGI NDETVFAKD+V
Sbjct: 604  NELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTSEDVPGSNITGIFNDETVFAKDEV 663

Query: 662  TCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLK 721
            TCVGHIIGAVVADTPEH  RAA+GVKITYE+LPAIITI+DAIKNNSFYGPE+KIEKGDLK
Sbjct: 664  TCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSFYGPEVKIEKGDLK 723

Query: 722  KGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKML 781
            KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSF+AKML
Sbjct: 724  KGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKML 783

Query: 782  GVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 841
            GVP NRIVVRVKRMGGGFGGKETRST++STAVALAAYKTGRPVRCMLDRDEDMLITGGRH
Sbjct: 784  GVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 843

Query: 842  PFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRL 901
            PFLA+YKVGFMKTGT+VALEV HFSN GN++DLS+SIMERA+FHMDN YKIPNIRGTGR+
Sbjct: 844  PFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNIRGTGRI 903

Query: 902  CKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLE 961
            CKTNLPSNTAFRGFGGPQGMLIAE WMSEVAVTCG+PAEEVRRKN+YKEGDLTHFNQKLE
Sbjct: 904  CKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKLE 963

Query: 962  GFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGAL 1021
            GFTLPRCW+EC+ASSQY ARK EV+KFN+ENCWKKRGLCIIPTKFGISFT+ FLNQ GAL
Sbjct: 964  GFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGAL 1023

Query: 1022 LHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAAS 1081
            +HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI+I+ETSTNTVPNTSPTAAS
Sbjct: 1024 VHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAAS 1083

Query: 1082 VSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGY 1141
             SADLNGQA+Y ACQTILKRLEP+KKKNPSGSWE WV  AY   VSLSATGFY+TPNLGY
Sbjct: 1084 ASADLNGQAIYEACQTILKRLEPFKKKNPSGSWESWVMDAYTSAVSLSATGFYKTPNLGY 1143

Query: 1142 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1201
            SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV
Sbjct: 1144 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1203

Query: 1202 QGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVG 1261
            QGLGLFT+EELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSL+RDCPNK+AIYASKAVG
Sbjct: 1204 QGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLVRDCPNKRAIYASKAVG 1263

Query: 1262 EPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTG 1321
            EPPLFLA+SIFFAIKDAIRAARAQH  +N K+LF+LDSPATPEKIRNACVD+FTTLC TG
Sbjct: 1264 EPPLFLASSIFFAIKDAIRAARAQHGDSNAKQLFQLDSPATPEKIRNACVDQFTTLCATG 1323

Query: 1322 VPENCKPWSVRV 1333
             PENCK WSVR+
Sbjct: 1324 TPENCKSWSVRI 1335
>emb|CAA44705.1| xanthine dehydrogenase [Mus musculus]
          Length = 1335

 Score = 2475 bits (6414), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1189/1332 (89%), Positives = 1269/1332 (95%), Gaps = 1/1332 (0%)

Query: 2    TADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRL 61
            T D+LVFFVNG+KVVEKNADPETTLL YLRRKLGL GTKLGCGEGGCGACTVM+SKYDRL
Sbjct: 5    TVDELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRL 64

Query: 62   QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIV 121
            QNKIVHFS NACL PICSLHHVAVTTVEGIG+TK +LHPVQERIAKSHGSQCGFCTPGIV
Sbjct: 65   QNKIVHFSVNACLTPICSLHHVAVTTVEGIGNTK-KLHPVQERIAKSHGSQCGFCTPGIV 123

Query: 122  MSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCM 181
            MSMYTLLRN+PEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG GNNPNCCM
Sbjct: 124  MSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCM 183

Query: 182  NQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAST 241
            +Q KD +++ S SLF PE+F PLDPTQEPIFPPELLRLKDTPRK LRFEGERVTWIQ ST
Sbjct: 184  SQTKDQTIAPSSSLFNPEDFKPLDPTQEPIFPPELLRLKDTPRKTLRFEGERVTWIQIST 243

Query: 242  LKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGA 301
            ++ELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP+I+CPAWI EL SV HGP+GISFGA
Sbjct: 244  MEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGA 303

Query: 302  ACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDL 361
            ACPLS+VE  L DA+A LP Q+TEVFRGV+EQLRWFAGKQVKSVAS+GGNIITASPISDL
Sbjct: 304  ACPLSLVESVLADAIATLPEQRTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDL 363

Query: 362  NPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAF 421
            NPV MAS AKLTL SRGT+RTV MDHTFFPGYR+TLLSPEEIL+SI IPYSR+GE+FSAF
Sbjct: 364  NPVLMASRAKLTLASRGTKRTVWMDHTFFPGYRRTLLSPEEILVSIVIPYSRKGEFFSAF 423

Query: 422  KQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEE 481
            KQASRREDDIAKVTSGMRVLFKPGTTEVQEL+LC+GGMA+RT+SALKTT +QLSK W EE
Sbjct: 424  KQASRREDDIAKVTSGMRVLFKPGTTEVQELSLCFGGMADRTVSALKTTPKQLSKSWNEE 483

Query: 482  LLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDP 541
            LLQDVCAGLAEELHL PDAPGGMV+FR TLTLSFFFKFYLTVLQKLG+ +LE  CGKLDP
Sbjct: 484  LLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEGMCGKLDP 543

Query: 542  TFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYE 601
            TFASATLLFQKDPPA+VQLFQEVPKGQSEEDMVGRP+PHLAADMQASGEAVYCDDIPRYE
Sbjct: 544  TFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDDIPRYE 603

Query: 602  NELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKV 661
            NELSLRLVTSTRAHAKI SIDTSEAKKVPGFVCF++++DVPGSNITGI NDETVFAKD+V
Sbjct: 604  NELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSNITGIFNDETVFAKDEV 663

Query: 662  TCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLK 721
            TCVGHIIGAVVADTPEH  RAA+GVKITYE+LPAIITI+DAIKNNSFYGPE+KIEKGDLK
Sbjct: 664  TCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSFYGPEVKIEKGDLK 723

Query: 722  KGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKML 781
            KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSF+AKML
Sbjct: 724  KGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKML 783

Query: 782  GVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 841
            GVP NRIVVRVKRMGGGFGGKETRST++STAVALAAYKTGRPVRCMLDRDEDMLITGGRH
Sbjct: 784  GVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 843

Query: 842  PFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRL 901
            PFLA+YKVGFMKTGT+VALEV HFSN GN++DLS+SIMERA+FHMDN YKIPNIRGTGR+
Sbjct: 844  PFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNIRGTGRI 903

Query: 902  CKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLE 961
            CKTNLPSNTAFRGFGGPQGMLIAE WMSEVAVTCG+PAEEVRRKN+YKEGDLTHFNQKLE
Sbjct: 904  CKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKLE 963

Query: 962  GFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGAL 1021
            GFTLPRCW+EC+ASSQY ARK EV+KFN+ENCWKKRGLCIIPTKFGISFT+ FLNQ GAL
Sbjct: 964  GFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGAL 1023

Query: 1022 LHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAAS 1081
            +HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI+I+ETSTNTVPNTSPTAAS
Sbjct: 1024 VHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAAS 1083

Query: 1082 VSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGY 1141
             SADLNGQA+Y ACQTILKRLEP+KKKNPSGSWE WV  AY   VSLSATGFY+TPNLGY
Sbjct: 1084 ASADLNGQAIYEACQTILKRLEPFKKKNPSGSWESWVMDAYTSAVSLSATGFYKTPNLGY 1143

Query: 1142 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1201
            SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV
Sbjct: 1144 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1203

Query: 1202 QGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVG 1261
            QGLGLFT+EELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSL+RDCPNK+AIYASKAVG
Sbjct: 1204 QGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLVRDCPNKRAIYASKAVG 1263

Query: 1262 EPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTG 1321
            EPPLFLA+SIFFAIKDAIRAARAQH  +N K+LF+LDSPATPEKIRNACVD+FTTLC TG
Sbjct: 1264 EPPLFLASSIFFAIKDAIRAARAQHGDSNAKQLFQLDSPATPEKIRNACVDQFTTLCATG 1323

Query: 1322 VPENCKPWSVRV 1333
             PENCK WSVR+
Sbjct: 1324 TPENCKSWSVRI 1335
>gb|EDL38417.1| xanthine dehydrogenase, isoform CRA_a [Mus musculus]
          Length = 1343

 Score = 2475 bits (6414), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1190/1332 (89%), Positives = 1269/1332 (95%), Gaps = 1/1332 (0%)

Query: 2    TADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRL 61
            T D+LVFFVNG+KVVEKNADPETTLL YLRRKLGL GTKLGCGEGGCGACTVM+SKYDRL
Sbjct: 13   TVDELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRL 72

Query: 62   QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIV 121
            QNKIVHFS NACL PICSLHHVAVTTVEGIG+TK +LHPVQERIAKSHGSQCGFCTPGIV
Sbjct: 73   QNKIVHFSVNACLTPICSLHHVAVTTVEGIGNTK-KLHPVQERIAKSHGSQCGFCTPGIV 131

Query: 122  MSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCM 181
            MSMYTLLRN+PEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG GNNPNCCM
Sbjct: 132  MSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCM 191

Query: 182  NQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAST 241
            +Q KD +++ S SLF PE+F PLDPTQEPIFPPELLRLKDTPRK LRFEGERVTWIQ ST
Sbjct: 192  SQTKDQTIAPSSSLFNPEDFKPLDPTQEPIFPPELLRLKDTPRKTLRFEGERVTWIQVST 251

Query: 242  LKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGA 301
            ++ELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP+I+CPAWI EL SV HGP+GISFGA
Sbjct: 252  MEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGA 311

Query: 302  ACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDL 361
            ACPLS+VE  L DA+A LP Q+TEVFRGV+EQLRWFAGKQVKSVAS+GGNIITASPISDL
Sbjct: 312  ACPLSLVESVLADAIATLPEQRTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDL 371

Query: 362  NPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAF 421
            NPV MAS AKLTL SRGT+RTV MDHTFFPGYR+TLLSPEEIL+SI IPYSR+GE+FSAF
Sbjct: 372  NPVLMASRAKLTLASRGTKRTVWMDHTFFPGYRRTLLSPEEILVSIVIPYSRKGEFFSAF 431

Query: 422  KQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEE 481
            KQASRREDDIAKVTSGMRVLFKPGTTEVQEL+LC+GGMA+RT+SALKTT +QLSK W EE
Sbjct: 432  KQASRREDDIAKVTSGMRVLFKPGTTEVQELSLCFGGMADRTVSALKTTPKQLSKSWNEE 491

Query: 482  LLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDP 541
            LLQDVCAGLAEELHL PDAPGGMV+FR TLTLSFFFKFYLTVLQKLG+ +LE  CGKLDP
Sbjct: 492  LLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEGMCGKLDP 551

Query: 542  TFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYE 601
            TFASATLLFQKDPPA+VQLFQEVPKGQSEEDMVGRP+PHLAADMQASGEAVYCDDIPRYE
Sbjct: 552  TFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDDIPRYE 611

Query: 602  NELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKV 661
            NELSLRLVTSTRAHAKI SIDTSEAKKVPGFVCF++++DVPGSNITGI NDETVFAKD+V
Sbjct: 612  NELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSNITGIFNDETVFAKDEV 671

Query: 662  TCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLK 721
            TCVGHIIGAVVADTPEH  RAA+GVKITYE+LPAIITI+DAIKNNSFYGPE+KIEKGDLK
Sbjct: 672  TCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSFYGPEVKIEKGDLK 731

Query: 722  KGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKML 781
            KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSF+AKML
Sbjct: 732  KGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKML 791

Query: 782  GVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 841
            GVP NRIVVRVKRMGGGFGGKETRST++STAVALAAYKTGRPVRCMLDRDEDMLITGGRH
Sbjct: 792  GVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 851

Query: 842  PFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRL 901
            PFLA+YKVGFMKTGT+VALEV HFSN GN++DLS+SIMERA+FHMDN YKIPNIRGTGR+
Sbjct: 852  PFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNIRGTGRI 911

Query: 902  CKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLE 961
            CKTNLPSNTAFRGFGGPQGMLIAE WMSEVAVTCG+PAEEVRRKN+YKEGDLTHFNQKLE
Sbjct: 912  CKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKLE 971

Query: 962  GFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGAL 1021
            GFTLPRCW+EC+ASSQY ARK EV+KFN+ENCWKKRGLCIIPTKFGISFT+ FLNQ GAL
Sbjct: 972  GFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGAL 1031

Query: 1022 LHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAAS 1081
            +HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI+I+ETSTNTVPNTSPTAAS
Sbjct: 1032 VHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAAS 1091

Query: 1082 VSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGY 1141
             SADLNGQA+Y ACQTILKRLEP+KKKNPSGSWE WV  AY   VSLSATGFY+TPNLGY
Sbjct: 1092 ASADLNGQAIYEACQTILKRLEPFKKKNPSGSWESWVMDAYTSAVSLSATGFYKTPNLGY 1151

Query: 1142 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1201
            SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV
Sbjct: 1152 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1211

Query: 1202 QGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVG 1261
            QGLGLFT+EELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNK+AIYASKAVG
Sbjct: 1212 QGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVG 1271

Query: 1262 EPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTG 1321
            EPPLFLA+SIFFAIKDAIRAARAQH  +N K+LF+LDSPATPEKIRNACVD+FTTLC TG
Sbjct: 1272 EPPLFLASSIFFAIKDAIRAARAQHGDSNAKQLFQLDSPATPEKIRNACVDQFTTLCATG 1331

Query: 1322 VPENCKPWSVRV 1333
             PENCK WSVR+
Sbjct: 1332 TPENCKSWSVRI 1343
>dbj|BAE26022.1| unnamed protein product [Mus musculus]
          Length = 1335

 Score = 2472 bits (6408), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1189/1332 (89%), Positives = 1268/1332 (95%), Gaps = 1/1332 (0%)

Query: 2    TADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRL 61
            T D+LVFFVNG+KVVEKNADPETTLL YLRRKLGL GTKLGCGEGGCGACTVM+SKYDRL
Sbjct: 5    TVDELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRL 64

Query: 62   QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIV 121
            QNKIVHFS NACL PICSLHHVAVTTVEGIG+TK +LHPVQERIAKSHGSQCGFCTPGIV
Sbjct: 65   QNKIVHFSVNACLTPICSLHHVAVTTVEGIGNTK-KLHPVQERIAKSHGSQCGFCTPGIV 123

Query: 122  MSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCM 181
            MSMYTLLRN+PEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+DGGCCGG GNNPNCCM
Sbjct: 124  MSMYTLLRNKPEPTVEEIENAFQGNLCRCTGYRPILQGFRTFAKDGGCCGGSGNNPNCCM 183

Query: 182  NQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAST 241
            +Q KD +++ S SLF PE+F PLDPTQEPIFPPELLRLKDTPRK LRFEGERVTWIQ ST
Sbjct: 184  SQTKDQTIAPSSSLFNPEDFKPLDPTQEPIFPPELLRLKDTPRKTLRFEGERVTWIQVST 243

Query: 242  LKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGA 301
            ++ELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP+I+CPAWI EL SV HGP+GISFGA
Sbjct: 244  MEELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPLIICPAWILELTSVAHGPEGISFGA 303

Query: 302  ACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDL 361
            ACPLS+VE  L DA+A LP Q+TEVFRGV+EQLRWFAGKQVKSVAS+GGNIITASPISDL
Sbjct: 304  ACPLSLVESVLADAIATLPEQRTEVFRGVMEQLRWFAGKQVKSVASIGGNIITASPISDL 363

Query: 362  NPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAF 421
            NPV MAS AKLTL SRGT+RTV MDHTFFPGYR+TLLSPEEIL+SI IPYSR+GE+FSAF
Sbjct: 364  NPVLMASRAKLTLASRGTKRTVWMDHTFFPGYRRTLLSPEEILVSIVIPYSRKGEFFSAF 423

Query: 422  KQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEE 481
            KQASRREDDIAKVTSGMRVLFKPGTTEVQEL+LC+GGMA+RT+SALKTT +QLSK W EE
Sbjct: 424  KQASRREDDIAKVTSGMRVLFKPGTTEVQELSLCFGGMADRTVSALKTTPKQLSKSWNEE 483

Query: 482  LLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDP 541
            LLQDVCAGLAEELHL PDAPGGMV+FR TLTLSFFFKFYLTVLQKLG+ +LE  CGKLDP
Sbjct: 484  LLQDVCAGLAEELHLAPDAPGGMVEFRRTLTLSFFFKFYLTVLQKLGRADLEGMCGKLDP 543

Query: 542  TFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYE 601
            TFASATLLFQKDPPA+VQLFQEVPKGQSEEDMVGRP+PHLAADMQASGEAVYCDDIPRYE
Sbjct: 544  TFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCDDIPRYE 603

Query: 602  NELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKV 661
            NELSLRLVTSTRAHAKI SIDTSEAKKVPGFVCF++++DVPGSNITGI NDETVFAKD+V
Sbjct: 604  NELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSNITGIFNDETVFAKDEV 663

Query: 662  TCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLK 721
            TCVGHIIGAVVADTPEH  RAA+GVKITYE+LPAIITI+DAIKNNSFYGPE+KIEKGDLK
Sbjct: 664  TCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSFYGPEVKIEKGDLK 723

Query: 722  KGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKML 781
            KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSF+AKML
Sbjct: 724  KGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFIAKML 783

Query: 782  GVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 841
            GVP NRIVVRVKRMGGGFGGKETRST++STAVALAAYKTGRPVRCMLDRDEDMLITGGRH
Sbjct: 784  GVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 843

Query: 842  PFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRL 901
            PFLA+YKVGFMKTGT+VALEV HFSN GN++DLS+SIMERA+ HMDN YKIPNIRGTGR+
Sbjct: 844  PFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVSHMDNAYKIPNIRGTGRI 903

Query: 902  CKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLE 961
            CKTNLPSNTAFRGFGGPQGMLIAE WMSEVAVTCG+PAEEVRRKN+YKEGDLTHFNQKLE
Sbjct: 904  CKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTHFNQKLE 963

Query: 962  GFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGAL 1021
            GFTLPRCW+EC+ASSQY ARK EV+KFN+ENCWKKRGLCIIPTKFGISFT+ FLNQ GAL
Sbjct: 964  GFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFLNQGGAL 1023

Query: 1022 LHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAAS 1081
            +HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI+I+ETSTNTVPNTSPTAAS
Sbjct: 1024 VHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNTSPTAAS 1083

Query: 1082 VSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGY 1141
             SADLNGQA+Y ACQTILKRLEP+KKKNPSGSWE WV  AY   VSLSATGFY+TPNLGY
Sbjct: 1084 ASADLNGQAIYEACQTILKRLEPFKKKNPSGSWESWVMDAYTSAVSLSATGFYKTPNLGY 1143

Query: 1142 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1201
            SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV
Sbjct: 1144 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1203

Query: 1202 QGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVG 1261
            QGLGLFT+EELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNK+AIYASKAVG
Sbjct: 1204 QGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVG 1263

Query: 1262 EPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTG 1321
            EPPLFLA+SIFFAIKDAIRAARAQH  +N K+LF+LDSPATPEKIRNACVD+FTTLC TG
Sbjct: 1264 EPPLFLASSIFFAIKDAIRAARAQHGDSNAKQLFQLDSPATPEKIRNACVDQFTTLCATG 1323

Query: 1322 VPENCKPWSVRV 1333
             PENCK WSVR+
Sbjct: 1324 TPENCKSWSVRI 1335
>sp|P80457|XDH_BOVIN Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase
            (XD); Xanthine oxidase (XO) (Xanthine oxidoreductase)]
          Length = 1332

 Score = 2472 bits (6408), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1195/1333 (89%), Positives = 1269/1333 (95%), Gaps = 1/1333 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKLGL GTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLRGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQ+KI+HFSANACLAPIC+LHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQDKIIHFSANACLAPICTLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIE+AFQGNLCRCTGYRPILQGFRTFA++GGCCGG+GNNPNCC
Sbjct: 121  VMSMYTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRTFAKNGGCCGGNGNNPNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQKKDH+V+LSPSLF PEEF PLDPTQEPIFPPELLRLKD P KQLRFEGERVTWIQAS
Sbjct: 181  MNQKKDHTVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPPKQLRFEGERVTWIQAS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMI+CPAWIPELN+VEHGP+GISFG
Sbjct: 241  TLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNQLFPMIICPAWIPELNAVEHGPEGISFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            AAC LS VEKTL++AVAKLP QKTEVFRGVLEQLRWFAGKQVKSVAS+GGNIITASPISD
Sbjct: 301  AACALSSVEKTLLEAVAKLPTQKTEVFRGVLEQLRWFAGKQVKSVASLGGNIITASPISD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASG KLT+VSRGTRRTV MDHTFFP YRKTLL PEEILLSIEIPYSRE E+FSA
Sbjct: 361  LNPVFMASGTKLTIVSRGTRRTVPMDHTFFPSYRKTLLGPEEILLSIEIPYSREDEFFSA 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVT GMRVLF+PG+ +V+ELALCYGGMA+RTISALKTTQ+QLSK W E
Sbjct: 421  FKQASRREDDIAKVTCGMRVLFQPGSMQVKELALCYGGMADRTISALKTTQKQLSKFWNE 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            +LLQDVCAGLAEEL L PDAPGGM++FR TLTLSFFFKFYLTVL+KLG+++ +DKCGKLD
Sbjct: 481  KLLQDVCAGLAEELSLSPDAPGGMIEFRRTLTLSFFFKFYLTVLKKLGKDS-KDKCGKLD 539

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PT+ SATLLFQKDPPA++QLFQEVP GQS+ED VGRPLPHLAA MQASGEAVYCDDIPRY
Sbjct: 540  PTYTSATLLFQKDPPANIQLFQEVPNGQSKEDTVGRPLPHLAAAMQASGEAVYCDDIPRY 599

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENEL LRLVTSTRAHAKIKSID SEA+KVPGFVCF+SADD+PGSN TG+ NDETVFAKD 
Sbjct: 600  ENELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKDT 659

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVVADTPEH +RAA  VK+TYE+LPAIITIEDAIKNNSFYG ELKIEKGDL
Sbjct: 660  VTCVGHIIGAVVADTPEHAERAAHVVKVTYEDLPAIITIEDAIKNNSFYGSELKIEKGDL 719

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGE+YIGGQ+HFYLETHCTIA+PKGE GEMELFVSTQN MKTQSFVAKM
Sbjct: 720  KKGFSEADNVVSGELYIGGQDHFYLETHCTIAIPKGEEGEMELFVSTQNAMKTQSFVAKM 779

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVP NRI+VRVKRMGGGFGGKETRST+VS AVALAAYKTG PVRCMLDR+EDMLITGGR
Sbjct: 780  LGVPVNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGGR 839

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTGT+VALEVDH+SN GN++DLS SIMERALFHMDNCYKIPNIRGTGR
Sbjct: 840  HPFLARYKVGFMKTGTIVALEVDHYSNAGNSRDLSHSIMERALFHMDNCYKIPNIRGTGR 899

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            LCKTNL SNTAFRGFGGPQ + IAE WMSEVAVTCG+PAEEVR KN+YKEGDLTHFNQ+L
Sbjct: 900  LCKTNLSSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRWKNMYKEGDLTHFNQRL 959

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGF++PRCW+ECL SSQY+ARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA
Sbjct: 960  EGFSVPRCWDECLKSSQYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1019

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVL++HGGTEMGQGLHTKMVQVAS+ALKIP SKIYISETSTNTVPN+SPTAA
Sbjct: 1020 LIHVYTDGSVLVSHGGTEMGQGLHTKMVQVASKALKIPISKIYISETSTNTVPNSSPTAA 1079

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVS D+ GQAVY ACQTILKRLEP+KKKNP GSWEDWV AAY D VSLS TGFYRTPNLG
Sbjct: 1080 SVSTDIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNLG 1139

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGN FHYF+YGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1140 YSFETNSGNAFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1199

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIP EFRVSLLRDCPNKKAIYASKAV
Sbjct: 1200 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPTEFRVSLLRDCPNKKAIYASKAV 1259

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFL AS+FFAIKDAIRAARAQHT NN KELFRLDSPATPEKIRNACVDKFTTLCVT
Sbjct: 1260 GEPPLFLGASVFFAIKDAIRAARAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCVT 1319

Query: 1321 GVPENCKPWSVRV 1333
            G P NCKPWS+RV
Sbjct: 1320 GAPGNCKPWSLRV 1332
>ref|NP_776397.1| xanthine dehydrogenase [Bos taurus]
 pdb|1FO4|A Chain A, Crystal Structure Of Xanthine Dehydrogenase Isolated From
            Bovine Milk
 pdb|1FO4|B Chain B, Crystal Structure Of Xanthine Dehydrogenase Isolated From
            Bovine Milk
 pdb|1V97|A Chain A, Crystal Structure Of Bovine Milk Xanthine Dehydrogenase Fyx-
            051 Bound Form
 pdb|1V97|B Chain B, Crystal Structure Of Bovine Milk Xanthine Dehydrogenase Fyx-
            051 Bound Form
 pdb|1VDV|A Chain A, Bovine Milk Xanthine Dehydrogenase Y-700 Bound Form
 pdb|1VDV|B Chain B, Bovine Milk Xanthine Dehydrogenase Y-700 Bound Form
 emb|CAA58497.1| xanthine dehydrogenase; xanthine oxidase [Bos taurus]
          Length = 1332

 Score = 2469 bits (6400), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1194/1333 (89%), Positives = 1268/1333 (95%), Gaps = 1/1333 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKLGL GTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLRGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQ+KI+HFSANACLAPIC+LHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQDKIIHFSANACLAPICTLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIE+AFQGNLCRCTGYRPILQGFRTFA++GGCCGG+GNNPNCC
Sbjct: 121  VMSMYTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRTFAKNGGCCGGNGNNPNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQKKDH+V+LSPSLF PEEF PLDPTQEPIFPPELLRLKD P KQLRFEGERVTWIQAS
Sbjct: 181  MNQKKDHTVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPPKQLRFEGERVTWIQAS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMI+CPAWIPELN+VEHGP+GISFG
Sbjct: 241  TLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNQLFPMIICPAWIPELNAVEHGPEGISFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            AAC LS VEKTL++AVAKLP QKTEVFRGVLEQLRWFAGKQVKSVAS+GGNIITASPISD
Sbjct: 301  AACALSSVEKTLLEAVAKLPTQKTEVFRGVLEQLRWFAGKQVKSVASLGGNIITASPISD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASG KLT+VSRGTRRTV MDHTFFP YRKTLL PEEILLSIEIPYSRE E+FSA
Sbjct: 361  LNPVFMASGTKLTIVSRGTRRTVPMDHTFFPSYRKTLLGPEEILLSIEIPYSREDEFFSA 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQASRREDDIAKVT GMRVLF+PG+ +V+ELALCYGGMA+RTISALKTTQ+QLSK W E
Sbjct: 421  FKQASRREDDIAKVTCGMRVLFQPGSMQVKELALCYGGMADRTISALKTTQKQLSKFWNE 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            +LLQDVCAGLAEEL L PDAPGGM++FR TLTLSFFFKFYLTVL+KLG+++ +DKCGKLD
Sbjct: 481  KLLQDVCAGLAEELSLSPDAPGGMIEFRRTLTLSFFFKFYLTVLKKLGKDS-KDKCGKLD 539

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PT+ SATLLFQK PPA++QLFQEVP GQS+ED VGRPLPHLAA MQASGEAVYCDDIPRY
Sbjct: 540  PTYTSATLLFQKHPPANIQLFQEVPNGQSKEDTVGRPLPHLAAAMQASGEAVYCDDIPRY 599

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENEL LRLVTSTRAHAKIKSID SEA+KVPGFVCF+SADD+PGSN TG+ NDETVFAKD 
Sbjct: 600  ENELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKDT 659

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVVADTPEH +RAA  VK+TYE+LPAIITIEDAIKNNSFYG ELKIEKGDL
Sbjct: 660  VTCVGHIIGAVVADTPEHAERAAHVVKVTYEDLPAIITIEDAIKNNSFYGSELKIEKGDL 719

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGE+YIGGQ+HFYLETHCTIA+PKGE GEMELFVSTQN MKTQSFVAKM
Sbjct: 720  KKGFSEADNVVSGELYIGGQDHFYLETHCTIAIPKGEEGEMELFVSTQNAMKTQSFVAKM 779

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVP NRI+VRVKRMGGGFGGKETRST+VS AVALAAYKTG PVRCMLDR+EDMLITGGR
Sbjct: 780  LGVPVNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGGR 839

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTGT+VALEVDH+SN GN++DLS SIMERALFHMDNCYKIPNIRGTGR
Sbjct: 840  HPFLARYKVGFMKTGTIVALEVDHYSNAGNSRDLSHSIMERALFHMDNCYKIPNIRGTGR 899

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            LCKTNL SNTAFRGFGGPQ + IAE WMSEVAVTCG+PAEEVR KN+YKEGDLTHFNQ+L
Sbjct: 900  LCKTNLSSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRWKNMYKEGDLTHFNQRL 959

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGF++PRCW+ECL SSQY+ARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA
Sbjct: 960  EGFSVPRCWDECLKSSQYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1019

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVL++HGGTEMGQGLHTKMVQVAS+ALKIP SKIYISETSTNTVPN+SPTAA
Sbjct: 1020 LIHVYTDGSVLVSHGGTEMGQGLHTKMVQVASKALKIPISKIYISETSTNTVPNSSPTAA 1079

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVS D+ GQAVY ACQTILKRLEP+KKKNP GSWEDWV AAY D VSLS TGFYRTPNLG
Sbjct: 1080 SVSTDIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNLG 1139

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGN FHYF+YGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF
Sbjct: 1140 YSFETNSGNAFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1199

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIP EFRVSLLRDCPNKKAIYASKAV
Sbjct: 1200 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPTEFRVSLLRDCPNKKAIYASKAV 1259

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFL AS+FFAIKDAIRAARAQHT NN KELFRLDSPATPEKIRNACVDKFTTLCVT
Sbjct: 1260 GEPPLFLGASVFFAIKDAIRAARAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCVT 1319

Query: 1321 GVPENCKPWSVRV 1333
            G P NCKPWS+RV
Sbjct: 1320 GAPGNCKPWSLRV 1332
>pdb|1N5X|A Chain A, Xanthine Dehydrogenase From Bovine Milk With Inhibitor Tei-
            6720 Bound
 pdb|1N5X|B Chain B, Xanthine Dehydrogenase From Bovine Milk With Inhibitor Tei-
            6720 Bound
          Length = 1331

 Score = 2467 bits (6394), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1193/1332 (89%), Positives = 1267/1332 (95%), Gaps = 1/1332 (0%)

Query: 2    TADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRL 61
            TAD+LVFFVNG+KVVEKNADPETTLLAYLRRKLGL GTKLGCGEGGCGACTVMLSKYDRL
Sbjct: 1    TADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLRGTKLGCGEGGCGACTVMLSKYDRL 60

Query: 62   QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIV 121
            Q+KI+HFSANACLAPIC+LHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIV
Sbjct: 61   QDKIIHFSANACLAPICTLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIV 120

Query: 122  MSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCM 181
            MSMYTLLRNQPEPT+EEIE+AFQGNLCRCTGYRPILQGFRTFA++GGCCGG+GNNPNCCM
Sbjct: 121  MSMYTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRTFAKNGGCCGGNGNNPNCCM 180

Query: 182  NQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAST 241
            NQKKDH+V+LSPSLF PEEF PLDPTQEPIFPPELLRLKD P KQLRFEGERVTWIQAST
Sbjct: 181  NQKKDHTVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPPKQLRFEGERVTWIQAST 240

Query: 242  LKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGA 301
            LKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMI+CPAWIPELN+VEHGP+GISFGA
Sbjct: 241  LKELLDLKAQHPEAKLVVGNTEIGIEMKFKNQLFPMIICPAWIPELNAVEHGPEGISFGA 300

Query: 302  ACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDL 361
            AC LS VEKTL++AVAKLP QKTEVFRGVLEQLRWFAGKQVKSVAS+GGNIITASPISDL
Sbjct: 301  ACALSSVEKTLLEAVAKLPTQKTEVFRGVLEQLRWFAGKQVKSVASLGGNIITASPISDL 360

Query: 362  NPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAF 421
            NPVFMASG KLT+VSRGTRRTV MDHTFFP YRKTLL PEEILLSIEIPYSRE E+FSAF
Sbjct: 361  NPVFMASGTKLTIVSRGTRRTVPMDHTFFPSYRKTLLGPEEILLSIEIPYSREDEFFSAF 420

Query: 422  KQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEE 481
            KQASRREDDIAKVT GMRVLF+PG+ +V+ELALCYGGMA+RTISALKTTQ+QLSK W E+
Sbjct: 421  KQASRREDDIAKVTCGMRVLFQPGSMQVKELALCYGGMADRTISALKTTQKQLSKFWNEK 480

Query: 482  LLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDP 541
            LLQDVCAGLAEEL L PDAPGGM++FR TLTLSFFFKFYLTVL+KLG+++ +DKCGKLDP
Sbjct: 481  LLQDVCAGLAEELSLSPDAPGGMIEFRRTLTLSFFFKFYLTVLKKLGKDS-KDKCGKLDP 539

Query: 542  TFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYE 601
            T+ SATLLFQK PPA++QLFQEVP GQS+ED VGRPLPHLAA MQASGEAVYCDDIPRYE
Sbjct: 540  TYTSATLLFQKHPPANIQLFQEVPNGQSKEDTVGRPLPHLAAAMQASGEAVYCDDIPRYE 599

Query: 602  NELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKV 661
            NEL LRLVTSTRAHAKIKSID SEA+KVPGFVCF+SADD+PGSN TG+ NDETVFAKD V
Sbjct: 600  NELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKDTV 659

Query: 662  TCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLK 721
            TCVGHIIGAVVADTPEH +RAA  VK+TYE+LPAIITIEDAIKNNSFYG ELKIEKGDLK
Sbjct: 660  TCVGHIIGAVVADTPEHAERAAHVVKVTYEDLPAIITIEDAIKNNSFYGSELKIEKGDLK 719

Query: 722  KGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKML 781
            KGFSEADNVVSGE+YIGGQ+HFYLETHCTIA+PKGE GEMELFVSTQN MKTQSFVAKML
Sbjct: 720  KGFSEADNVVSGELYIGGQDHFYLETHCTIAIPKGEEGEMELFVSTQNAMKTQSFVAKML 779

Query: 782  GVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRH 841
            GVP NRI+VRVKRMGGGFGGKETRST+VS AVALAAYKTG PVRCMLDR+EDMLITGGRH
Sbjct: 780  GVPVNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGGRH 839

Query: 842  PFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRL 901
            PFLARYKVGFMKTGT+VALEVDH+SN GN++DLS SIMERALFHMDNCYKIPNIRGTGRL
Sbjct: 840  PFLARYKVGFMKTGTIVALEVDHYSNAGNSRDLSHSIMERALFHMDNCYKIPNIRGTGRL 899

Query: 902  CKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLE 961
            CKTNL SNTAFRGFGGPQ + IAE WMSEVAVTCG+PAEEVR KN+YKEGDLTHFNQ+LE
Sbjct: 900  CKTNLSSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRWKNMYKEGDLTHFNQRLE 959

Query: 962  GFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGAL 1021
            GF++PRCW+ECL SSQY+ARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGAL
Sbjct: 960  GFSVPRCWDECLKSSQYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGAL 1019

Query: 1022 LHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAAS 1081
            +HVYTDGSVL++HGGTEMGQGLHTKMVQVAS+ALKIP SKIYISETSTNTVPN+SPTAAS
Sbjct: 1020 IHVYTDGSVLVSHGGTEMGQGLHTKMVQVASKALKIPISKIYISETSTNTVPNSSPTAAS 1079

Query: 1082 VSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGY 1141
            VS D+ GQAVY ACQTILKRLEP+KKKNP GSWEDWV AAY D VSLS TGFYRTPNLGY
Sbjct: 1080 VSTDIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNLGY 1139

Query: 1142 SFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1201
            SFETNSGN FHYF+YGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV
Sbjct: 1140 SFETNSGNAFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFV 1199

Query: 1202 QGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVG 1261
            QGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIP EFRVSLLRDCPNKKAIYASKAVG
Sbjct: 1200 QGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPTEFRVSLLRDCPNKKAIYASKAVG 1259

Query: 1262 EPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTG 1321
            EPPLFL AS+FFAIKDAIRAARAQHT NN KELFRLDSPATPEKIRNACVDKFTTLCVTG
Sbjct: 1260 EPPLFLGASVFFAIKDAIRAARAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCVTG 1319

Query: 1322 VPENCKPWSVRV 1333
             P NCKPWS+RV
Sbjct: 1320 APGNCKPWSLRV 1331
>gb|AAD17938.1| xanthine:oxygen oxidoreductase [Tragelaphus oryx]
          Length = 1332

 Score = 2454 bits (6360), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1190/1333 (89%), Positives = 1259/1333 (94%), Gaps = 1/1333 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTA +LVFFVNG+KVVEKNADPETTLLAYLRRKLGL GTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTAGELVFFVNGKKVVEKNADPETTLLAYLRRKLGLRGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQ+KI+HFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQDKIIHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIE+AFQGNLCRCTGYRPILQGFRTFA++GGCCGG+GNNPNCC
Sbjct: 121  VMSMYTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRTFAKNGGCCGGNGNNPNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            MNQKKDH+V+LSPSLF PEEF PLDPTQEPIFPPELLRLKD P KQLRFEGERVTWIQ+S
Sbjct: 181  MNQKKDHTVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPPKQLRFEGERVTWIQSS 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFP+I+CPAWIPELN+VEHGP+GISFG
Sbjct: 241  TLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNQLFPVIICPAWIPELNAVEHGPEGISFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            AAC LS +EKTL +AVAKLP QKTEVFRGVLEQLRWFAGKQ KSVAS+GGNIITASPISD
Sbjct: 301  AACTLSSLEKTLFEAVAKLPTQKTEVFRGVLEQLRWFAGKQFKSVASIGGNIITASPISD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFMASG KLT+VSRGTRRTV MDHTFFP YRKTLL PEEILLSIEIPYSRE E+FSA
Sbjct: 361  LNPVFMASGTKLTIVSRGTRRTVPMDHTFFPSYRKTLLGPEEILLSIEIPYSREDEFFSA 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQA+RREDDIAKVT GMRVLF+PG+T+V+ELALCYGGMA+RTISALKTTQRQLSK W E
Sbjct: 421  FKQAARREDDIAKVTCGMRVLFQPGSTQVKELALCYGGMADRTISALKTTQRQLSKFWNE 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            +LLQDVCAGLAEEL L PDAPGGM++FR TLTLSFFFKFYLTVL+KLG+++ ED C KLD
Sbjct: 481  KLLQDVCAGLAEELALSPDAPGGMIEFRRTLTLSFFFKFYLTVLKKLGKDS-EDSCDKLD 539

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PT  SATLLFQKDPPA +QLFQEVPKGQS+ED VG+PLPHLAA MQASGEAVYCDDIPRY
Sbjct: 540  PTDTSATLLFQKDPPASIQLFQEVPKGQSKEDTVGQPLPHLAAAMQASGEAVYCDDIPRY 599

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
            ENEL LRLVTSTRAHAKIKSID SEA+KVPGFVCF+SADD+PGSN TG+ NDETVFAKD 
Sbjct: 600  ENELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGVFNDETVFAKDT 659

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDL 720
            VTCVGHIIGAVV DTPEH QRAA  VK+TYE+LPAIITIEDAIKNNSFYG E KIEKGDL
Sbjct: 660  VTCVGHIIGAVVTDTPEHAQRAAHAVKVTYEDLPAIITIEDAIKNNSFYGSEQKIEKGDL 719

Query: 721  KKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKM 780
            KKGFSEADNVVSGE+YIGGQ+HFYLETHCTIAVPKGE GEMELFVSTQN MKTQSFVAKM
Sbjct: 720  KKGFSEADNVVSGELYIGGQDHFYLETHCTIAVPKGEEGEMELFVSTQNAMKTQSFVAKM 779

Query: 781  LGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGR 840
            LGVP NRI+VRVKRMGGGFGGKETRST+VS AVALAAYKTG PVRCMLDR+EDMLITGGR
Sbjct: 780  LGVPVNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGGR 839

Query: 841  HPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGR 900
            HPFLARYKVGFMKTG +VALEVDH+SN GN+ DLS SIMERALFHMDNCYKIPNIRGTGR
Sbjct: 840  HPFLARYKVGFMKTGKIVALEVDHYSNAGNSLDLSHSIMERALFHMDNCYKIPNIRGTGR 899

Query: 901  LCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKL 960
            LCKTNL SNTAFRGFG PQ MLIAE WMSEVAVTCG+PAEEVR KNLYKEGDLTHFNQ+L
Sbjct: 900  LCKTNLSSNTAFRGFGAPQAMLIAENWMSEVAVTCGLPAEEVRSKNLYKEGDLTHFNQRL 959

Query: 961  EGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGA 1020
            EGF++PRCW+ECL SSQY+ARKSEVDKFNKENCWKKRGLCIIPTKFGISFT+PFLNQAGA
Sbjct: 960  EGFSVPRCWDECLQSSQYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTIPFLNQAGA 1019

Query: 1021 LLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAA 1080
            L+HVYTDGSVL++HGGTEMGQGLHTKMVQVAS+ALKIP SKIYISETSTNTVPN+ PTAA
Sbjct: 1020 LIHVYTDGSVLVSHGGTEMGQGLHTKMVQVASKALKIPISKIYISETSTNTVPNSCPTAA 1079

Query: 1081 SVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLG 1140
            SVS D+ GQAVY ACQTILKRLEP+KKKNP GSWEDWV AAY D VSLS TGFYRTPNLG
Sbjct: 1080 SVSTDIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNLG 1139

Query: 1141 YSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAF 1200
            YSFETNSGNPFHYF+YGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEG F
Sbjct: 1140 YSFETNSGNPFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGGF 1199

Query: 1201 VQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAV 1260
            VQGLGLFT+EELHYSPEGSLHT GPSTYKIPAFGSIP EFRVSLLRDCPNKKAIYASKAV
Sbjct: 1200 VQGLGLFTMEELHYSPEGSLHTSGPSTYKIPAFGSIPTEFRVSLLRDCPNKKAIYASKAV 1259

Query: 1261 GEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVT 1320
            GEPPLFL ASIFFAIKDAIRAARAQHT NN KELFRLDSPATPEKIRNACVDKFTTLCVT
Sbjct: 1260 GEPPLFLGASIFFAIKDAIRAARAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCVT 1319

Query: 1321 GVPENCKPWSVRV 1333
             VPENCKPWS+RV
Sbjct: 1320 RVPENCKPWSLRV 1332
>gb|AAD17937.1| xanthine:oxygen oxidoreductase [Syncerus caffer]
          Length = 1328

 Score = 2449 bits (6347), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1183/1329 (89%), Positives = 1259/1329 (94%), Gaps = 1/1329 (0%)

Query: 5    KLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNK 64
            +LVFFVNG+KVVEKNADPETTLLAYLRRKLGL GTKLGCGEGGCGACTVMLSKYDRLQ+K
Sbjct: 1    ELVFFVNGKKVVEKNADPETTLLAYLRRKLGLRGTKLGCGEGGCGACTVMLSKYDRLQDK 60

Query: 65   IVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSM 124
            I+HFSANACLAPIC+LHHVAVTTVEGIGSTKTRLHPVQERIAKSH  QCGFCTPGIVMSM
Sbjct: 61   IIHFSANACLAPICTLHHVAVTTVEGIGSTKTRLHPVQERIAKSHDCQCGFCTPGIVMSM 120

Query: 125  YTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMNQK 184
            YTLLRNQPEPT+EEIE+AFQGNLCRCTGYRPILQGFR FA++GGCCGG+GNNPNCCMNQK
Sbjct: 121  YTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRIFAKNGGCCGGNGNNPNCCMNQK 180

Query: 185  KDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQASTLKE 244
            KDH+V+LSPSLF PEEF PLDPTQEPIFPPELLRLKD P KQLRFEGERVTWIQASTLKE
Sbjct: 181  KDHTVTLSPSLFNPEEFMPLDPTQEPIFPPELLRLKDVPPKQLRFEGERVTWIQASTLKE 240

Query: 245  LLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGAACP 304
            LLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMI+CPAWIPELN+VEHGP+GI FGAAC 
Sbjct: 241  LLDLKAQHPEAKLVVGNTEIGIEMKFKNQLFPMIICPAWIPELNAVEHGPEGIPFGAACT 300

Query: 305  LSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDLNPV 364
            LS VEKTL++AVAKLP QKTEVFRGVLEQLRWFAGKQVKSVAS+GGNIITASPISDLNPV
Sbjct: 301  LSSVEKTLLEAVAKLPTQKTEVFRGVLEQLRWFAGKQVKSVASIGGNIITASPISDLNPV 360

Query: 365  FMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAFKQA 424
            FMASG KLT+VSRGTRRTV MDHTFFP YRKTLL PEEILLS+EIPYSRE E+FSAFKQA
Sbjct: 361  FMASGTKLTIVSRGTRRTVPMDHTFFPSYRKTLLGPEEILLSLEIPYSREDEFFSAFKQA 420

Query: 425  SRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEELLQ 484
            +RREDDIAKVT GMRVLF+PG+T+V+ELALCYGGMA+RTISALKTTQRQLSK W E LLQ
Sbjct: 421  NRREDDIAKVTCGMRVLFQPGSTQVKELALCYGGMADRTISALKTTQRQLSKFWNENLLQ 480

Query: 485  DVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDPTFA 544
            DVCAGLAEEL L P+APGGM++FR TLTLSFFFKFYLTVL+KLG+E+  DKCGKLDPT+ 
Sbjct: 481  DVCAGLAEELSLSPEAPGGMIEFRRTLTLSFFFKFYLTVLKKLGKES-NDKCGKLDPTYT 539

Query: 545  SATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYENEL 604
            SATLL QKDPPA++QLFQEVP GQS+ED VGRPLPHLAA MQASGEAVYCDDIPRYENEL
Sbjct: 540  SATLLSQKDPPANIQLFQEVPNGQSKEDTVGRPLPHLAAAMQASGEAVYCDDIPRYENEL 599

Query: 605  SLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKVTCV 664
             LRLVTSTRAHAKI+SID SEA+KVPGFVCF+SADD+PGSN TG+ NDETVFAKD VTCV
Sbjct: 600  FLRLVTSTRAHAKIRSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKDTVTCV 659

Query: 665  GHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLKKGF 724
            GHIIGAVVADTPEH QRAA  VK+TYE+LPAIITIEDAIKNNSFYG EL+IEKGDLKKGF
Sbjct: 660  GHIIGAVVADTPEHAQRAAHAVKVTYEDLPAIITIEDAIKNNSFYGSELRIEKGDLKKGF 719

Query: 725  SEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVP 784
            SEADNVVSGE+YIGGQ+HFYLETHCTIAVPKGE GEMELFVSTQN MKTQSFVAKMLGVP
Sbjct: 720  SEADNVVSGELYIGGQDHFYLETHCTIAVPKGEEGEMELFVSTQNAMKTQSFVAKMLGVP 779

Query: 785  ANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFL 844
             NRI+VRVKRMGGGFGGKETRST+VS AVALAAYKTG PVRCMLDR+EDMLITGGRHPFL
Sbjct: 780  VNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGGRHPFL 839

Query: 845  ARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKT 904
            ARYKVGFMKTG +VALEVDH+SN GN++DLS SIMERALFHMDNCY IPNIRGTGRLCKT
Sbjct: 840  ARYKVGFMKTGKIVALEVDHYSNAGNSRDLSHSIMERALFHMDNCYNIPNIRGTGRLCKT 899

Query: 905  NLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFT 964
            NL SNTAFRGFGGPQ + IAE WMSEVAVTCG+PAEEVR KNLYKEGDLTHFNQ+LEGF+
Sbjct: 900  NLSSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRSKNLYKEGDLTHFNQRLEGFS 959

Query: 965  LPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALLHV 1024
            +PRCW+ECL SSQY+ARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGAL+HV
Sbjct: 960  VPRCWDECLKSSQYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALIHV 1019

Query: 1025 YTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAASVSA 1084
            YTDGSVL++HGGTEMGQGLHTKMVQVAS+ALKIP SKIYISETSTNTVPN+SPTAASVS 
Sbjct: 1020 YTDGSVLVSHGGTEMGQGLHTKMVQVASKALKIPISKIYISETSTNTVPNSSPTAASVST 1079

Query: 1085 DLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGYSFE 1144
            D+ GQAVY ACQTILKRLEP+KKKNP GSWEDWV AAY D VSLS TGFYRTPNLGYSFE
Sbjct: 1080 DIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNLGYSFE 1139

Query: 1145 TNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGL 1204
            TNSGN FHYF+YGVAC+EVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGL
Sbjct: 1140 TNSGNAFHYFTYGVACTEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGL 1199

Query: 1205 GLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVGEPP 1264
            GLFTLEELHYSPEGSL+TRGPSTYKIPAFGS+P+EFRVSLLRDCPNKKAIYASKAVGEPP
Sbjct: 1200 GLFTLEELHYSPEGSLYTRGPSTYKIPAFGSVPMEFRVSLLRDCPNKKAIYASKAVGEPP 1259

Query: 1265 LFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTGVPE 1324
            LFL AS+FFAIKDAIRAARAQHT NN KELFRLDSPATPEKIRNACVDKFTTLCVT VPE
Sbjct: 1260 LFLGASVFFAIKDAIRAARAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCVTCVPE 1319

Query: 1325 NCKPWSVRV 1333
            NCKPWS+RV
Sbjct: 1320 NCKPWSLRV 1328
>emb|CAA67117.1| xanthine dehydrogenase [Bos taurus]
          Length = 1332

 Score = 2446 bits (6338), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1186/1334 (88%), Positives = 1264/1334 (94%), Gaps = 3/1334 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKLGL GTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLGLRGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            LQ+KI+HFSANACLAPIC+LHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   LQDKIIHFSANACLAPICTLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VMSMYTLLRNQPEPT+EEIE+AFQGNLCRCTGYRPILQGFRTFA++GGCCGG+GNNPNCC
Sbjct: 121  VMSMYTLLRNQPEPTVEEIEDAFQGNLCRCTGYRPILQGFRTFAKNGGCCGGNGNNPNCC 180

Query: 181  MNQKKDHS-VSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQA 239
            MNQKKDH+ V+LSPSLF P+EF PLDPTQEPIFPPELLRLKD P KQLRFEGERVTWIQA
Sbjct: 181  MNQKKDHTQVTLSPSLFNPKEFMPLDPTQEPIFPPELLRLKDVPPKQLRFEGERVTWIQA 240

Query: 240  STLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISF 299
            STLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMI+CPAWIPELN+VEHGP+GISF
Sbjct: 241  STLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNQLFPMIICPAWIPELNAVEHGPEGISF 300

Query: 300  GAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPIS 359
            GAAC LS VEKTL++AVAKLP QKTEVFRGVLEQLRWFAGKQVKSVAS+GGNIITASPIS
Sbjct: 301  GAACALSSVEKTLLEAVAKLPTQKTEVFRGVLEQLRWFAGKQVKSVASLGGNIITASPIS 360

Query: 360  DLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFS 419
            DLNPVF+ASG KLT+VSRGTRRTV MDHTFFP YRKTLL PEEILLSIEIPYSRE E+FS
Sbjct: 361  DLNPVFVASGTKLTIVSRGTRRTVPMDHTFFPSYRKTLLGPEEILLSIEIPYSREDEFFS 420

Query: 420  AFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWK 479
            AFKQASRREDDIAKVT GMRVLF+PG+ +V+ELALCYGGMA+RTISALKTTQ+QLSK W 
Sbjct: 421  AFKQASRREDDIAKVTCGMRVLFQPGSMQVKELALCYGGMADRTISALKTTQKQLSKFWN 480

Query: 480  EELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKL 539
            E+LLQDVCAGLAEEL L PDAPGGM++FR TLTLSFFFKFYLTVL+KLG+++ +DKCGKL
Sbjct: 481  EKLLQDVCAGLAEELSLSPDAPGGMIEFRRTLTLSFFFKFYLTVLKKLGKDS-KDKCGKL 539

Query: 540  DPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPR 599
            DPT+ SATLLFQKDPPA++QLFQEVP GQS+ED VGRPLPHLAA MQASGEAVYCDDIPR
Sbjct: 540  DPTYTSATLLFQKDPPANIQLFQEVPNGQSKEDTVGRPLPHLAAAMQASGEAVYCDDIPR 599

Query: 600  YENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKD 659
            YENEL LRLVTSTRAHAKIKSID SEA+KVPGFVCF+SADD+PGSN TG+ NDETVFAKD
Sbjct: 600  YENELFLRLVTSTRAHAKIKSIDVSEAQKVPGFVCFLSADDIPGSNETGLFNDETVFAKD 659

Query: 660  KVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGD 719
             VTCVGHIIGAVVADTPEH +RAA  VK+TYE+LPAIITIEDAIKNNSFYG ELKIEKGD
Sbjct: 660  TVTCVGHIIGAVVADTPEHAERAAHVVKVTYEDLPAIITIEDAIKNNSFYGSELKIEKGD 719

Query: 720  LKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAK 779
            LKKGFSEADNVVSGE+YIGGQ+HFYLETHCTIA+PKGE GEMELFVSTQN MKTQSFVAK
Sbjct: 720  LKKGFSEADNVVSGELYIGGQDHFYLETHCTIAIPKGEEGEMELFVSTQNAMKTQSFVAK 779

Query: 780  MLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGG 839
            MLGVP NRI+VRVKRMGGGFGGKETRST+VS AVALAAYKTG PVRCMLDR+EDMLITGG
Sbjct: 780  MLGVPVNRILVRVKRMGGGFGGKETRSTLVSVAVALAAYKTGHPVRCMLDRNEDMLITGG 839

Query: 840  RHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTG 899
            RHPFLARYKVGFMKTGT+VALEVDH+SN GN++DLS SIMERALFHMDNCYKIPNIRGTG
Sbjct: 840  RHPFLARYKVGFMKTGTIVALEVDHYSNAGNSRDLSHSIMERALFHMDNCYKIPNIRGTG 899

Query: 900  RLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQK 959
            RLCKTNL SNTAFRGFGGPQ + IAE WMSEVAVTCG+PAEEVR KN+YKEGDLTHFNQK
Sbjct: 900  RLCKTNLSSNTAFRGFGGPQALFIAENWMSEVAVTCGLPAEEVRWKNMYKEGDLTHFNQK 959

Query: 960  LEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAG 1019
            LEGF++PRCW+ECL SS+Y+ARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAG
Sbjct: 960  LEGFSVPRCWDECLKSSEYYARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAG 1019

Query: 1020 ALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTA 1079
            AL+HVYTDGSVL++HGGTEM +GLHTKMVQVAS+ALKIP SKIYISETSTNTVPN+SPTA
Sbjct: 1020 ALIHVYTDGSVLVSHGGTEM-EGLHTKMVQVASKALKIPISKIYISETSTNTVPNSSPTA 1078

Query: 1080 ASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNL 1139
            ASVS D+ GQAVY ACQTILKRLEP+KKKNP GSWEDWV AAY D VSLS TGFYRTPNL
Sbjct: 1079 ASVSTDIYGQAVYEACQTILKRLEPFKKKNPDGSWEDWVMAAYQDRVSLSTTGFYRTPNL 1138

Query: 1140 GYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGA 1199
            GYSFETNSGN FHYF+YGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGA
Sbjct: 1139 GYSFETNSGNAFHYFTYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGA 1198

Query: 1200 FVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKA 1259
            FVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIP EFRVSL+RDCPNKKAIYASKA
Sbjct: 1199 FVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPTEFRVSLVRDCPNKKAIYASKA 1258

Query: 1260 VGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCV 1319
            VGEPPLFL  S+FFAIKDAI   RAQHT NN KELFRLDSPATPEKIRNACVDKFTTLCV
Sbjct: 1259 VGEPPLFLGPSVFFAIKDAIARGRAQHTNNNTKELFRLDSPATPEKIRNACVDKFTTLCV 1318

Query: 1320 TGVPENCKPWSVRV 1333
            TG P NCKPWS+RV
Sbjct: 1319 TGAPGNCKPWSLRV 1332
>ref|XP_862593.1| PREDICTED: similar to Xanthine dehydrogenase/oxidase isoform 4 [Canis
            familiaris]
          Length = 1334

 Score = 2442 bits (6329), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1186/1335 (88%), Positives = 1251/1335 (93%), Gaps = 3/1335 (0%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKL LSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
             QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTK+RLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   FQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARD--GGCCGGDGNNPN 178
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA+    G  G       
Sbjct: 121  VMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFAKKWWEGPKGRALRASG 180

Query: 179  CCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQ 238
              ++      V LSPSLF PEEF PLDPTQEPIFPPELL       KQL F+GERVTWIQ
Sbjct: 181  KAVSAGGPGRVILSPSLFNPEEFMPLDPTQEPIFPPELLVGGAQREKQLCFKGERVTWIQ 240

Query: 239  ASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGIS 298
            ASTLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMIVCPAWIPELN+VEHG +GIS
Sbjct: 241  ASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAWIPELNAVEHGLEGIS 300

Query: 299  FGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPI 358
            FGAACPLSIVEKTL DAV KLPA KTEVF+GVLEQLRWFAGKQVKSVAS+GGNII ASPI
Sbjct: 301  FGAACPLSIVEKTLHDAVNKLPAYKTEVFKGVLEQLRWFAGKQVKSVASIGGNIINASPI 360

Query: 359  SDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYF 418
            SDLNPVFMAS AKLT+VSRG +RTV+MDHTFFPGYRKTLL+PEEILLSIEIPYSREGE+F
Sbjct: 361  SDLNPVFMASEAKLTIVSRGIKRTVRMDHTFFPGYRKTLLAPEEILLSIEIPYSREGEFF 420

Query: 419  SAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLW 478
            SAFKQASRREDDIAKVTSGMRVLF PGT +V+ELALCYGGM +RTISALKTT++Q+  LW
Sbjct: 421  SAFKQASRREDDIAKVTSGMRVLFHPGTAQVKELALCYGGMDDRTISALKTTRKQVENLW 480

Query: 479  KEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGK 538
             E+LLQ+VCAGLAEEL L PDAPGGMVDFR TLTLSFFFKFYLTVLQKL + NLE+KCGK
Sbjct: 481  NEDLLQNVCAGLAEELKLSPDAPGGMVDFRRTLTLSFFFKFYLTVLQKLERGNLENKCGK 540

Query: 539  LDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIP 598
            LDPT+ASATLLFQKDPPA+VQLFQEVP+GQSEEDMVGRPLPHLAA MQASGEAVYCDDIP
Sbjct: 541  LDPTYASATLLFQKDPPANVQLFQEVPEGQSEEDMVGRPLPHLAAAMQASGEAVYCDDIP 600

Query: 599  RYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAK 658
            RYENELSLRLVTSTRAHAKIKSIDTSEA+KVPGFVCF+S +DVPGSN TGI NDET+FA+
Sbjct: 601  RYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPGSNKTGIFNDETIFAE 660

Query: 659  DKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKG 718
            D+VTC+GHIIGAVV DTPEH QRAAQGVKITYEELPAIITIEDAIKNNSFYG ELKIEKG
Sbjct: 661  DEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAIKNNSFYGSELKIEKG 720

Query: 719  DLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVA 778
            +L KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGE GE+ELF STQNTMKTQ+FVA
Sbjct: 721  ELTKGFSEADNVVSGEVYIGGQEHFYLETHCTIAVPKGEEGELELFASTQNTMKTQAFVA 780

Query: 779  KMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITG 838
             MLGVP NRI+VRVKRMGGGFGGKETRST+VST VALAAYKTGRPVRCMLDRDEDMLITG
Sbjct: 781  NMLGVPINRILVRVKRMGGGFGGKETRSTLVSTVVALAAYKTGRPVRCMLDRDEDMLITG 840

Query: 839  GRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGT 898
            GRHPFLA+YKVGFMKTG VVALEV+H+SN GNT DLSQSIMERALFHMDNCYKIPNIRGT
Sbjct: 841  GRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERALFHMDNCYKIPNIRGT 900

Query: 899  GRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQ 958
            GRLCKTNLPSNTAFRGFGGPQGMLIAE WMSEVA+TCG+PAEEVRRKN+YKEGDLTHFNQ
Sbjct: 901  GRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVRRKNMYKEGDLTHFNQ 960

Query: 959  KLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQA 1018
            KLEGFTL RCWEECLASSQYHARKSEVDKFN+EN WKKRGLCIIPTKFGISFT+ FLNQA
Sbjct: 961  KLEGFTLSRCWEECLASSQYHARKSEVDKFNEENYWKKRGLCIIPTKFGISFTLSFLNQA 1020

Query: 1019 GALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPT 1078
            GAL+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPT
Sbjct: 1021 GALIHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPT 1080

Query: 1079 AASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPN 1138
            AASVSAD+NGQAVY AC+TILKRLEP+KKKNPSGSWEDWV  AY +TVSLSATGFYRTPN
Sbjct: 1081 AASVSADINGQAVYEACKTILKRLEPFKKKNPSGSWEDWVIDAYENTVSLSATGFYRTPN 1140

Query: 1139 LGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEG 1198
            LGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEG
Sbjct: 1141 LGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEG 1200

Query: 1199 AFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASK 1258
            AFVQGLGLFTLEELHYSPEGSL TRGPSTYKIPAFG+IP EFRVSLLRDCPNKKAIYASK
Sbjct: 1201 AFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVSLLRDCPNKKAIYASK 1260

Query: 1259 AVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLC 1318
            AVGEPPLFLAAS+FFAIKDA+RAARA+++    K LFRLDSPATPEKIRNACVD+FTTLC
Sbjct: 1261 AVGEPPLFLAASVFFAIKDAVRAARARNSDCKTK-LFRLDSPATPEKIRNACVDEFTTLC 1319

Query: 1319 VTGVPENCKPWSVRV 1333
            VTG+PENCKPWSVRV
Sbjct: 1320 VTGIPENCKPWSVRV 1334
>ref|XP_862613.1| PREDICTED: similar to Xanthine dehydrogenase/oxidase isoform 5 [Canis
            familiaris]
          Length = 1333

 Score = 2435 bits (6312), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1184/1350 (87%), Positives = 1250/1350 (92%), Gaps = 34/1350 (2%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            MTAD+LVFFVNG+KVVEKNADPETTLLAYLRRKL LSGTKLGCGEGGCGACTVMLSKYDR
Sbjct: 1    MTADELVFFVNGKKVVEKNADPETTLLAYLRRKLRLSGTKLGCGEGGCGACTVMLSKYDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
             QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTK+RLHPVQERIAKSHGSQCGFCTPGI
Sbjct: 61   FQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKSRLHPVQERIAKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFA---------------- 164
            VMSMYTLLRNQPEPT+EEIENAFQGNLCRCTGYRPILQGFRTFA                
Sbjct: 121  VMSMYTLLRNQPEPTIEEIENAFQGNLCRCTGYRPILQGFRTFAKHLSLSSCPLPAAVCS 180

Query: 165  -RDGGCCGGDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTP 223
             R  GC G D   P+               +    EEF PLDPTQEPIFPPELL + D P
Sbjct: 181  WRSSGCAGTDSRTPD---------------THLPTEEFMPLDPTQEPIFPPELL-VGDVP 224

Query: 224  RKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAW 283
            +KQL F+GERVTWIQASTLKELLDLKAQHP+AKLVVGNTEIGIEMKFKN LFPMIVCPAW
Sbjct: 225  QKQLCFKGERVTWIQASTLKELLDLKAQHPEAKLVVGNTEIGIEMKFKNRLFPMIVCPAW 284

Query: 284  IPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVK 343
            IPELN+VEHG +GISFGAACPLSIVEKTL DAV KLPA KTEVF+GVLEQLRWFAGKQVK
Sbjct: 285  IPELNAVEHGLEGISFGAACPLSIVEKTLHDAVNKLPAYKTEVFKGVLEQLRWFAGKQVK 344

Query: 344  SVASVGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEI 403
            SVAS+GGNII ASPISDLNPVFMAS AKLT+VSRG +RTV+MDHTFFPGYRKTLL+PEEI
Sbjct: 345  SVASIGGNIINASPISDLNPVFMASEAKLTIVSRGIKRTVRMDHTFFPGYRKTLLAPEEI 404

Query: 404  LLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRT 463
            LLSIEIPYSREGE+FSAFKQASRREDDIAKVTSGMRVLF PGT +V+ELALCYGGM +RT
Sbjct: 405  LLSIEIPYSREGEFFSAFKQASRREDDIAKVTSGMRVLFHPGTAQVKELALCYGGMDDRT 464

Query: 464  ISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTV 523
            ISALKTT++Q+  LW E+LLQ+VCAGLAEEL L PDAPGGMVDFR TLTLSFFFKFYLTV
Sbjct: 465  ISALKTTRKQVENLWNEDLLQNVCAGLAEELKLSPDAPGGMVDFRRTLTLSFFFKFYLTV 524

Query: 524  LQKLGQENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAA 583
            LQKL + NLE+KCGKLDPT+ASATLLFQKDPPA+VQLFQEVP+GQSEEDMVGRPLPHLAA
Sbjct: 525  LQKLERGNLENKCGKLDPTYASATLLFQKDPPANVQLFQEVPEGQSEEDMVGRPLPHLAA 584

Query: 584  DMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPG 643
             MQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEA+KVPGFVCF+S +DVPG
Sbjct: 585  AMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAEKVPGFVCFLSFNDVPG 644

Query: 644  SNITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAI 703
            SN TGI NDET+FA+D+VTC+GHIIGAVV DTPEH QRAAQGVKITYEELPAIITIEDAI
Sbjct: 645  SNKTGIFNDETIFAEDEVTCIGHIIGAVVTDTPEHAQRAAQGVKITYEELPAIITIEDAI 704

Query: 704  KNNSFYGPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMEL 763
            KNNSFYG ELKIEKG+L KGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGE GE+EL
Sbjct: 705  KNNSFYGSELKIEKGELTKGFSEADNVVSGEVYIGGQEHFYLETHCTIAVPKGEEGELEL 764

Query: 764  FVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRP 823
            F STQNTMKTQ+FVA MLGVP NRI+VRVKRMGGGFGGKETRST+VST VALAAYKTGRP
Sbjct: 765  FASTQNTMKTQAFVANMLGVPINRILVRVKRMGGGFGGKETRSTLVSTVVALAAYKTGRP 824

Query: 824  VRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERAL 883
            VRCMLDRDEDMLITGGRHPFLA+YKVGFMKTG VVALEV+H+SN GNT DLSQSIMERAL
Sbjct: 825  VRCMLDRDEDMLITGGRHPFLAKYKVGFMKTGKVVALEVEHYSNAGNTLDLSQSIMERAL 884

Query: 884  FHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVR 943
            FHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAE WMSEVA+TCG+PAEEVR
Sbjct: 885  FHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAMTCGLPAEEVR 944

Query: 944  RKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIP 1003
            RKN+YKEGDLTHFNQKLEGFTL RCWEECLASSQYHARKSEVDKFN+EN WKKRGLCIIP
Sbjct: 945  RKNMYKEGDLTHFNQKLEGFTLSRCWEECLASSQYHARKSEVDKFNEENYWKKRGLCIIP 1004

Query: 1004 TKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIY 1063
            TKFGISFT+ FLNQAGAL+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIY
Sbjct: 1005 TKFGISFTLSFLNQAGALIHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIY 1064

Query: 1064 ISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYM 1123
            ISETSTNTVPNTSPTAASVSAD+NGQAVY AC+TILKRLEP+KKKNPSGSWEDWV  AY 
Sbjct: 1065 ISETSTNTVPNTSPTAASVSADINGQAVYEACKTILKRLEPFKKKNPSGSWEDWVIDAYE 1124

Query: 1124 DTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDV 1183
            +TVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDV
Sbjct: 1125 NTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDV 1184

Query: 1184 GSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVS 1243
            GSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSL TRGPSTYKIPAFG+IP EFRVS
Sbjct: 1185 GSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLQTRGPSTYKIPAFGNIPTEFRVS 1244

Query: 1244 LLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATP 1303
            LLRDCPNKKAIYASKAVGEPPLFLAAS+FFAIKDA+RAARA+++    K LFRLDSPATP
Sbjct: 1245 LLRDCPNKKAIYASKAVGEPPLFLAASVFFAIKDAVRAARARNSDCKTK-LFRLDSPATP 1303

Query: 1304 EKIRNACVDKFTTLCVTGVPENCKPWSVRV 1333
            EKIRNACVD+FTTLCVTG+PENCKPWSVRV
Sbjct: 1304 EKIRNACVDEFTTLCVTGIPENCKPWSVRV 1333
>ref|XP_001380730.1| PREDICTED: similar to xanthine dehydrogenase/oxidase [Monodelphis
            domestica]
          Length = 1356

 Score = 2228 bits (5774), Expect = 0.0,   Method: Composition-based stats.
 Identities = 1097/1388 (79%), Positives = 1197/1388 (86%), Gaps = 104/1388 (7%)

Query: 1    MTADKLVFFVNG---------------------------RKVVEKNADPETTLLAYLRRK 33
            M +D+LVFFVNG                           R+VVEKNA+PE TLL+YLRRK
Sbjct: 1    MASDELVFFVNGKKVSEGLTFGSVFHQEIMSNTLYWLQGRRVVEKNAEPEMTLLSYLRRK 60

Query: 34   LGLSGTKLGCGEGGCGACTVMLSKYDRLQNKIVHFSANACLAPICSLHHVAVTTVEGIGS 93
            L   GT+LGCGEGGCGACTVMLSK+DRLQ KIVHFS NACLAPICSLHHVAVTTVEGIGS
Sbjct: 61   LK-EGTELGCGEGGCGACTVMLSKFDRLQKKIVHFSVNACLAPICSLHHVAVTTVEGIGS 119

Query: 94   TKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGY 153
            TKTRLHPVQERI+KSHGSQCGFCTPGIVMSMYTLLRN PEPTMEEIENAFQGNLCRCTGY
Sbjct: 120  TKTRLHPVQERISKSHGSQCGFCTPGIVMSMYTLLRNNPEPTMEEIENAFQGNLCRCTGY 179

Query: 154  RPILQGFRTFARDGGCCGGDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFP 213
            RPILQGFRTFA+DGGCCGG G NPNCCM QK++  ++LS SLF  EEF PLDPTQEPIFP
Sbjct: 180  RPILQGFRTFAKDGGCCGGTGENPNCCMYQKENSKLNLSSSLFNSEEFLPLDPTQEPIFP 239

Query: 214  PELL---------------RLKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLV 258
            PEL+               RLKD P+KQL F+GERV WIQ +TLKELL+LKA+HPDAKLV
Sbjct: 240  PELMVSDTPKRGLNLCNLNRLKDEPQKQLCFQGERVKWIQTATLKELLELKAEHPDAKLV 299

Query: 259  VGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAK 318
            VGNTEIGIEMKFKN LFP+IVCPAWIPELNSV+ GP+      ACPLS +EK LV A+A+
Sbjct: 300  VGNTEIGIEMKFKNKLFPLIVCPAWIPELNSVKRGPE------ACPLSEMEKALVAAIAE 353

Query: 319  LPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVSRG 378
            LP+ +TEVF+GVLEQLRWFAGKQVKSVASVGGNII ASPISDLNPVFMASG+KLTLVS+G
Sbjct: 354  LPSYQTEVFKGVLEQLRWFAGKQVKSVASVGGNIINASPISDLNPVFMASGSKLTLVSKG 413

Query: 379  TRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGM 438
            T+RTV+MDH FFP YRKTLLSPEEILLSIEIPYSR+GEYFSAFKQASRREDDIAKVT GM
Sbjct: 414  TKRTVRMDHMFFPSYRKTLLSPEEILLSIEIPYSRKGEYFSAFKQASRREDDIAKVTCGM 473

Query: 439  RVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPP 498
            RVLFKP + +VQEL + +GGMA++TI ALKTT++Q  + W EELLQ+VCA LAEEL L P
Sbjct: 474  RVLFKPESDQVQELDISFGGMADKTIPALKTTRKQQGRAWNEELLQEVCASLAEELSLEP 533

Query: 499  DAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDPTFASATLLFQKDPPADV 558
            DAPGGMV+FR TLTLSFFFKFYLTVLQKLG+++  DKC KLDPT+ASATLLFQK+PPA+V
Sbjct: 534  DAPGGMVEFRRTLTLSFFFKFYLTVLQKLGKDS-TDKCDKLDPTYASATLLFQKEPPANV 592

Query: 559  QLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKI 618
            QLFQEVPKGQ+E+DMVGRPLPH +A   ASGE                           +
Sbjct: 593  QLFQEVPKGQAEDDMVGRPLPHFSAPNIASGEPA-------------------------V 627

Query: 619  KSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKVTCVGHIIGAVVADTPEH 678
             SID SEA+KVPGF+ F+SADD+PGSN TG+ NDETVFAK KVTCVGHIIGAVV DTPEH
Sbjct: 628  LSIDISEAQKVPGFIHFLSADDIPGSNETGLFNDETVFAKHKVTCVGHIIGAVVTDTPEH 687

Query: 679  TQRAAQGVKITYEELPAIITIEDAI---------------------KNNSFYGPELKIEK 717
             QRAAQ VKI YEELPAIITIE ++                     KNNSFYG ELKIEK
Sbjct: 688  AQRAAQAVKIEYEELPAIITIEPSLITAVVSSDCIAVGLFANLGRDKNNSFYGSELKIEK 747

Query: 718  GDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFV 777
            GDLKKGF+EADNVVSGE+YIGGQEHFYLETHCTIAVPKGE GEMELFVSTQNTMKTQSFV
Sbjct: 748  GDLKKGFAEADNVVSGELYIGGQEHFYLETHCTIAVPKGEEGEMELFVSTQNTMKTQSFV 807

Query: 778  AKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLIT 837
            AK+LGVP NRIVVRVKRMGGGFGGKETRSTV+STAVALAAYKTGRPVRCMLDRDEDMLIT
Sbjct: 808  AKVLGVPDNRIVVRVKRMGGGFGGKETRSTVLSTAVALAAYKTGRPVRCMLDRDEDMLIT 867

Query: 838  GGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRG 897
            GGRHPFLARYKVGFMKTG +VALEV+H+SN GNT DLSQSIMERALFHMDNCYKIPNIRG
Sbjct: 868  GGRHPFLARYKVGFMKTGKIVALEVEHYSNAGNTLDLSQSIMERALFHMDNCYKIPNIRG 927

Query: 898  TGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFN 957
             GRLCKTNL SNTAFRGFGGPQGMLIAE WMSEVA+TC +PAEEVRR N+YKEGDLTHFN
Sbjct: 928  IGRLCKTNLSSNTAFRGFGGPQGMLIAEYWMSEVALTCRLPAEEVRRLNMYKEGDLTHFN 987

Query: 958  QKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQ 1017
            QKLEGFTLPRCW+ECL SS+YHAR++E++ FNKENCWKKRGLCIIPTKFGISFTVPFLNQ
Sbjct: 988  QKLEGFTLPRCWDECLESSKYHARRNEIETFNKENCWKKRGLCIIPTKFGISFTVPFLNQ 1047

Query: 1018 AGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSP 1077
            AGAL+HVYTDGSVLLTHGGTEMGQGLHTKM+QVAS+ALKIPTSKIYISETST+TVPNTSP
Sbjct: 1048 AGALVHVYTDGSVLLTHGGTEMGQGLHTKMIQVASKALKIPTSKIYISETSTSTVPNTSP 1107

Query: 1078 TAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVT-------AAYMDTVSL-S 1129
            TAASVSAD+NGQAVY AC+TIL+RLEP+KKKNP+GSW+DWV+         Y ++V+L  
Sbjct: 1108 TAASVSADINGQAVYEACKTILQRLEPFKKKNPNGSWKDWVSLHLLKINKFYFNSVNLYM 1167

Query: 1130 ATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNP 1189
            +T F +TPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKN+RTDIVMDVGSSLNP
Sbjct: 1168 STSFLKTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNIRTDIVMDVGSSLNP 1227

Query: 1190 AIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCP 1249
            AIDIGQVEGAFVQGLGLFTLEELHYSPEG+LHTRGPSTYKIPAFG+IPI+FRVSLLRDCP
Sbjct: 1228 AIDIGQVEGAFVQGLGLFTLEELHYSPEGTLHTRGPSTYKIPAFGNIPIDFRVSLLRDCP 1287

Query: 1250 NKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNA 1309
            NKKAIYASKAVGEPPLFLA+SIFFAIKDAI AARAQH    +KELF+LDSPATPEKIRNA
Sbjct: 1288 NKKAIYASKAVGEPPLFLASSIFFAIKDAICAARAQHADFKMKELFQLDSPATPEKIRNA 1347

Query: 1310 CVDKFTTL 1317
            CVDKFTTL
Sbjct: 1348 CVDKFTTL 1355
>ref|NP_990458.1| xanthine dehydrogenase [Gallus gallus]
 sp|P47990|XDH_CHICK Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase
            (XD); Xanthine oxidase (XO) (Xanthine oxidoreductase)]
 dbj|BAA02502.1| xanthine dehydrogenase [Gallus gallus]
          Length = 1358

 Score = 2042 bits (5290), Expect = 0.0,   Method: Composition-based stats.
 Identities = 979/1356 (72%), Positives = 1133/1356 (83%), Gaps = 29/1356 (2%)

Query: 2    TADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRL 61
            T D+LVFFVNG+KVVEK+ DPETTLL YLRRKLGL GTKLGCGEGGCGACTVM+SKYD  
Sbjct: 6    TGDELVFFVNGKKVVEKDVDPETTLLTYLRRKLGLCGTKLGCGEGGCGACTVMISKYDPF 65

Query: 62   QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIV 121
            Q KI+H +ANACL PIC+LHHVAVTTVEGIG+TK+RLHP QERIAKSHGSQCGFCTPGIV
Sbjct: 66   QKKILHHTANACLFPICALHHVAVTTVEGIGNTKSRLHPAQERIAKSHGSQCGFCTPGIV 125

Query: 122  MSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARD--------------- 166
            MSMYTLLRN+P+P ME+IE+AFQGNLCRCTGYRPIL+G+RTFA D               
Sbjct: 126  MSMYTLLRNKPKPKMEDIEDAFQGNLCRCTGYRPILEGYRTFAVDSNCCGKAANGTGCCH 185

Query: 167  --------GGCCGGDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLR 218
                    GGCCGG  N P CCMN+K++ ++ +S SLF   EF PLDPTQEPIFPPEL+ 
Sbjct: 186  SKGENSMNGGCCGGKANGPGCCMNEKENVTM-MSSSLFDSSEFQPLDPTQEPIFPPELMT 244

Query: 219  LKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMI 278
             ++  +KQ+ F+GERV WIQ +TL+EL+ LK+Q+P+AKLVVGNTE+GIEM+ KNML+P+I
Sbjct: 245  QRNKEQKQVCFKGERVMWIQPTTLQELVALKSQYPNAKLVVGNTEVGIEMRLKNMLYPVI 304

Query: 279  VCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFA 338
            + PAWIPE+N+V+    GI+FGAAC LS VE+ L  AVA+LP+ KTE+F+  LEQLRWFA
Sbjct: 305  LAPAWIPEMNAVQQTETGITFGAACTLSSVEEVLRKAVAELPSYKTEIFQAALEQLRWFA 364

Query: 339  GKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLL 398
            G Q+++VA++GGNI+TASPISDLNPV MASG+KLTL+S   +RTV MD  FF GYRKT++
Sbjct: 365  GPQIRNVAALGGNIMTASPISDLNPVLMASGSKLTLISMEGKRTVMMDEKFFTGYRKTIV 424

Query: 399  SPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGG 458
             PEE+LLS+EIPYS+EGEYFSAFKQA RREDDIA VT GMRVLF+ GT+ VQE+ L YGG
Sbjct: 425  KPEEVLLSVEIPYSKEGEYFSAFKQAYRREDDIAIVTCGMRVLFQHGTSRVQEVKLSYGG 484

Query: 459  MANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFK 518
            MA  TI ALKT +    + W E+LLQD C  LA E+ L P APGGMV+FR TLTLSFFFK
Sbjct: 485  MAPTTILALKTCRELAGRDWNEKLLQDACRLLAGEMDLSPSAPGGMVEFRRTLTLSFFFK 544

Query: 519  FYLTVLQKLG--QENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGR 576
            FYLTVLQKL   Q    + C  + P + SAT LF KDP A  QLFQEVP+GQ  ED VGR
Sbjct: 545  FYLTVLQKLSKDQNGPNNLCEPVPPNYISATELFHKDPIASTQLFQEVPRGQLVEDTVGR 604

Query: 577  PLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFI 636
            PL HL+A  QA GEAVYCDDIP YENEL L LVTST+AHAKI SID SEA+ VPGFVCF+
Sbjct: 605  PLVHLSAAKQACGEAVYCDDIPHYENELYLTLVTSTQAHAKILSIDASEAQSVPGFVCFV 664

Query: 637  SADDVPGSNITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAI 696
            SA DVPGSNITGI NDETVFA+D VTCVGHIIGAV+ADT EH++RAA+ VKI YEEL  I
Sbjct: 665  SAKDVPGSNITGIANDETVFAEDVVTCVGHIIGAVIADTQEHSRRAAKAVKIKYEELKPI 724

Query: 697  ITIEDAIKNNSFYGPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKG 756
            +TI++AI+  SF  P  +I+KGD+ KGF E+D+++ GE++IGGQEHFYLETHCT+AVPKG
Sbjct: 725  VTIQEAIEQQSFIKPIKRIKKGDVNKGFEESDHILEGEMHIGGQEHFYLETHCTLAVPKG 784

Query: 757  EAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALA 816
            E GEMELFVSTQN MKTQ F A  LGVP+NRIVVRVKRMGGGFGGKETR+T+++T VA+A
Sbjct: 785  EDGEMELFVSTQNLMKTQEFTASALGVPSNRIVVRVKRMGGGFGGKETRNTILTTVVAVA 844

Query: 817  AYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQ 876
            A+KTGRPVRCMLDRDEDMLI+GGRHPFL RYKVGFMK G + +LEV ++SN GN+ DLS 
Sbjct: 845  AFKTGRPVRCMLDRDEDMLISGGRHPFLGRYKVGFMKNGKIKSLEVSYYSNGGNSADLSH 904

Query: 877  SIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCG 936
             +M+RAL H+DN Y IPN+   G +CKTNL SNTAFRGFGGPQGM+IAECWMS++A  CG
Sbjct: 905  GVMDRALLHLDNSYNIPNVSIMGFICKTNLSSNTAFRGFGGPQGMMIAECWMSDLARKCG 964

Query: 937  MPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKK 996
            +P EEVR+ NLY EGDLTHFNQKLEGFTL RCW+ECL+SS YHARK  +++FNK+N WKK
Sbjct: 965  LPPEEVRKINLYHEGDLTHFNQKLEGFTLRRCWDECLSSSNYHARKKLIEEFNKQNRWKK 1024

Query: 997  RGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALK 1056
            RG+CIIPTKFGISFTVPFLNQAGAL+HVYTDGSVLLTHGGTEMGQGLHTKM+QVASR+L 
Sbjct: 1025 RGMCIIPTKFGISFTVPFLNQAGALVHVYTDGSVLLTHGGTEMGQGLHTKMIQVASRSLG 1084

Query: 1057 IPTSKIYISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWED 1116
            IPTSKIYISETSTNTVPNTSPTAASVSAD+NG AV+ ACQTILKRLEP K+ N  GSWED
Sbjct: 1085 IPTSKIYISETSTNTVPNTSPTAASVSADINGMAVHNACQTILKRLEPIKQSNLKGSWED 1144

Query: 1117 WVTAAYMDTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLR 1176
            W+  AY + +SLSATGFYR P++GY+FETN G PFHYFSYGVACSEVEIDCLTGDHKN+R
Sbjct: 1145 WIKTAYENCISLSATGFYRIPDVGYNFETNKGKPFHYFSYGVACSEVEIDCLTGDHKNIR 1204

Query: 1177 TDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSI 1236
            TDIVMDVG+SLNPAIDIGQ+EGAFVQG+GLFT+EEL YSPEG+L+TRGP  YKIPAFG I
Sbjct: 1205 TDIVMDVGTSLNPAIDIGQIEGAFVQGIGLFTMEELRYSPEGNLYTRGPGMYKIPAFGDI 1264

Query: 1237 PIEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFR 1296
            P EF VSLLRDCPN KAIY+SKAVGEPPLFL+AS+F+AIKDAI +AR     + V E FR
Sbjct: 1265 PTEFYVSLLRDCPNSKAIYSSKAVGEPPLFLSASVFYAIKDAIYSARED---SGVTEPFR 1321

Query: 1297 LDSPATPEKIRNACVDKFTTLCVTGVPENCKPWSVR 1332
            LDSPATPE+IRNACVD FT +C +  P   KPWSVR
Sbjct: 1322 LDSPATPERIRNACVDTFTKMCPSAEPGTFKPWSVR 1357
>ref|XP_001509432.1| PREDICTED: similar to xanthine oxidoreductase [Ornithorhynchus
            anatinus]
          Length = 1297

 Score = 1971 bits (5106), Expect = 0.0,   Method: Composition-based stats.
 Identities = 935/1336 (69%), Positives = 1095/1336 (81%), Gaps = 42/1336 (3%)

Query: 1    MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDR 60
            M AD+LVFFVNG+KV+EKNADPETTLL YLRRKLGL+GTKLGCG G CGACTVMLS++DR
Sbjct: 1    MAADELVFFVNGKKVMEKNADPETTLLVYLRRKLGLNGTKLGCGTGACGACTVMLSRFDR 60

Query: 61   LQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGI 120
            L+ K++HF+ANACLAPIC+LHHVAVTTVEGIGSTKT++HPVQERI+KSHGSQCGFCTPGI
Sbjct: 61   LKKKVIHFTANACLAPICALHHVAVTTVEGIGSTKTKMHPVQERISKSHGSQCGFCTPGI 120

Query: 121  VMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCC 180
            VM MYTLLRN PEP+MEEIENAFQGNLCRCTGYRPIL+G RTFA+D GC GG   + NCC
Sbjct: 121  VMGMYTLLRNNPEPSMEEIENAFQGNLCRCTGYRPILEGLRTFAKDRGCLGGKEKDSNCC 180

Query: 181  MNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQAS 240
            +N+++  +++LSPSLF  EEF PLDPTQEPIFPPELL LKD PR+QLRF+GERVTWIQA+
Sbjct: 181  LNKEEKSTITLSPSLFNSEEFLPLDPTQEPIFPPELLLLKDAPRRQLRFQGERVTWIQAA 240

Query: 241  TLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFG 300
            TL+ELLDLKAQHPDA LVVGNT++GIEMKF N +FP+I+CPAWIPELN+VEH  +GISFG
Sbjct: 241  TLEELLDLKAQHPDAMLVVGNTKVGIEMKFGNKVFPVIICPAWIPELNAVEHRTEGISFG 300

Query: 301  AACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISD 360
            A+C LS +E+TL  AVA LPA KTEVF+G+LEQ+RWF+GKQVKSVAS+GGNII ASP SD
Sbjct: 301  ASCTLSSMEETLAAAVATLPAHKTEVFQGILEQMRWFSGKQVKSVASIGGNIIVASPNSD 360

Query: 361  LNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSA 420
            LNPVFM SGAKLTLVS+G RRT++MDHTFF G+R+T+LSP+EILLSIEIPYS+E EYFS 
Sbjct: 361  LNPVFMVSGAKLTLVSKGKRRTIRMDHTFFTGFRRTILSPQEILLSIEIPYSQENEYFSV 420

Query: 421  FKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            FKQ SR ++D AKVT GMRVLFK GTT+VQ+L + +GG+ ++T+ AL+T ++Q  + W E
Sbjct: 421  FKQISRHDEDFAKVTCGMRVLFKQGTTQVQKLEMSFGGLGDKTLQALETPRKQTGRFWDE 480

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
             LL D+CAGL EEL L PDA GG V+FR TLTLSFFFKFYL+VLQKL + ++  KC  LD
Sbjct: 481  SLLADMCAGLEEELRLAPDARGGKVEFRRTLTLSFFFKFYLSVLQKLNKCSVRGKCCNLD 540

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
            PT+ SA   FQKDP A+VQLFQEVPKGQSEED VGRPL HLAA MQA+GEAVYCDDIP Y
Sbjct: 541  PTWLSALAPFQKDPVANVQLFQEVPKGQSEEDTVGRPLAHLAAAMQATGEAVYCDDIPPY 600

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDK 660
             NEL LRLVTST+AHAKIKSID SEA+KVPGFV F+SA D+PGSN+TG+ NDETVFA  +
Sbjct: 601  SNELYLRLVTSTKAHAKIKSIDASEAQKVPGFVHFLSAADIPGSNVTGLENDETVFADGE 660

Query: 661  VTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPEL--KIEKG 718
            VTCVGHIIGA++ADTPEH QRAA+ V+I YEELPAII+I+DAIKN SFY       +EKG
Sbjct: 661  VTCVGHIIGAMLADTPEHAQRAAEAVRIAYEELPAIISIKDAIKNKSFYKISFLSTMEKG 720

Query: 719  DLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVA 778
            DL+KGF+EAD ++ G    GG+ HF+ +TH  IA+PKGE GEME+FV++Q  M  Q FVA
Sbjct: 721  DLQKGFAEADQILEGTGIFGGKTHFFFQTHSCIAIPKGEEGEMEIFVASQCPMVLQDFVA 780

Query: 779  KMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITG 838
            K L VP+NRI VRVKR+GGGFGGK++ S ++ T +A+AA+KTGRPVRCMLDRDEDML+TG
Sbjct: 781  KALDVPSNRITVRVKRLGGGFGGKDSSSALLCTVLAVAAHKTGRPVRCMLDRDEDMLVTG 840

Query: 839  GRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGT 898
            GRHPF+A YKVGFMK G VVALE+D+++N GN+  +S S+M +AL H+DNCYKIPNIR T
Sbjct: 841  GRHPFMACYKVGFMKDGRVVALEIDYYNNAGNSVAISSSVMNKALHHLDNCYKIPNIRAT 900

Query: 899  GRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQ 958
            G+LCKTNLPSNTAFR FGGPQ +LI E WMSEVA+ CG P EEVRR N+Y++GDLTHF+Q
Sbjct: 901  GKLCKTNLPSNTAFRAFGGPQALLITESWMSEVAMKCGCPPEEVRRLNMYRDGDLTHFDQ 960

Query: 959  KLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQA 1018
            KL G TL RCW ECL SSQYHAR+ E++KFN+E  WKK GL IIP KFG  F+ PF NQ 
Sbjct: 961  KLVGSTLSRCWSECLESSQYHARRREIEKFNREVFWKKGGLAIIPIKFGPGFSFPFSNQV 1020

Query: 1019 GAL-LHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSP 1077
            G   LH++  G +  + GG+     LH  ++QVASR L IP SKIYISETSTNTVPNTS 
Sbjct: 1021 GRYCLHLFRPGELAESGGGSLQHHFLHLFVLQVASRVLGIPISKIYISETSTNTVPNTSA 1080

Query: 1078 TAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTP 1137
            T+AS+  DLNG AV                       + W                  TP
Sbjct: 1081 TSASLGTDLNGMAV-----------------------QVWTC----------------TP 1101

Query: 1138 NLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVE 1197
            NLGY FETNSGNPF+YF YGVACSEVEIDCLTGD++N+RTDIVMDVG+SLNPAIDIGQVE
Sbjct: 1102 NLGYDFETNSGNPFNYFCYGVACSEVEIDCLTGDYQNIRTDIVMDVGTSLNPAIDIGQVE 1161

Query: 1198 GAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYAS 1257
            GAFVQGLGLFTLEELHYSPEG L TRG  +YKIPA G IP +F V+LLRDCPN+KAI++S
Sbjct: 1162 GAFVQGLGLFTLEELHYSPEGKLLTRGLDSYKIPACGDIPTKFHVTLLRDCPNQKAIFSS 1221

Query: 1258 KAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTL 1317
            KAVGEPPLFL+ASIFFAIKDAI AARAQ + + +  LF+LDS ATPE+IRNACVD+FT L
Sbjct: 1222 KAVGEPPLFLSASIFFAIKDAIGAARAQGSESQLDPLFQLDSLATPERIRNACVDRFTKL 1281

Query: 1318 CVTGVPENCKPWSVRV 1333
            C T VP N KPW  RV
Sbjct: 1282 CGTEVPANFKPWCKRV 1297
>ref|XP_001515925.1| PREDICTED: similar to xanthine dehydrogenase/oxidase, partial
            [Ornithorhynchus anatinus]
          Length = 1005

 Score = 1624 bits (4205), Expect = 0.0,   Method: Composition-based stats.
 Identities = 753/1005 (74%), Positives = 869/1005 (86%), Gaps = 2/1005 (0%)

Query: 15   VVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNKIVHFSANACL 74
            VVEKNADPETTLL YLRRKLGL+GTKLGCG G CGACTVMLSK+DRLQNK+VHF+ANACL
Sbjct: 1    VVEKNADPETTLLVYLRRKLGLNGTKLGCGTGFCGACTVMLSKFDRLQNKVVHFTANACL 60

Query: 75   APICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEP 134
            APICSLHHVAVTTVEGIGSTKT+LHPVQERI+KSHGSQCGFCTPGIVMSMYTLLRN PEP
Sbjct: 61   APICSLHHVAVTTVEGIGSTKTKLHPVQERISKSHGSQCGFCTPGIVMSMYTLLRNNPEP 120

Query: 135  TMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMNQKKDHSVSLSPS 194
            +MEEIENAFQGNLCRCTGYRPIL+GFRTFA+D GCCGG G +PNCC+N+++  +V+LSPS
Sbjct: 121  SMEEIENAFQGNLCRCTGYRPILEGFRTFAKDRGCCGGKGKDPNCCLNKEEKSTVTLSPS 180

Query: 195  LFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPD 254
            LF P EF PLDPTQEPIFPPELL LKD PR+QLRF+GERVTWIQA+TL+ELLDLKAQH D
Sbjct: 181  LFNPGEFLPLDPTQEPIFPPELLLLKDAPRRQLRFQGERVTWIQAATLEELLDLKAQHSD 240

Query: 255  AKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVD 314
            A LVVGNT +GIEMKF N +FP+I+CPAWIPELN+VEHG +GISFGA+C LS +E+TL  
Sbjct: 241  AVLVVGNTRVGIEMKFGNKVFPIIICPAWIPELNAVEHGTEGISFGASCTLSSLEETLEA 300

Query: 315  AVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTL 374
            AVA LPA KTEVF+G+LEQ+RWF+GKQVKSVAS+GGN+I ASP SD NPVFMASGAKLTL
Sbjct: 301  AVATLPAHKTEVFQGILEQMRWFSGKQVKSVASIGGNVIAASPNSDFNPVFMASGAKLTL 360

Query: 375  VSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKV 434
            VS+G RRTV+MD TFF G+RK +L+P+EILLSIEIPYS++ EYFSAFKQ SR ++D AKV
Sbjct: 361  VSKGKRRTVRMDQTFFTGFRKMILTPQEILLSIEIPYSQKNEYFSAFKQISRHDEDFAKV 420

Query: 435  TSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEEL 494
            T GMRV FK  TT+VQ+L + +GG+ ++T+ AL+T+++Q  + W E LL DVCAGL EE 
Sbjct: 421  TCGMRVQFKQDTTQVQKLEMSFGGLGDKTLQALETSRKQTGRFWDESLLADVCAGLEEEF 480

Query: 495  HLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDPTFASATLLFQKDP 554
             L PDA GGMV+FR  LTLSFFFKFY++VLQKL + ++  KCG LDPT+ SA   FQK P
Sbjct: 481  RLAPDARGGMVEFRRMLTLSFFFKFYISVLQKLKKCSVRGKCGSLDPTWLSAVAPFQKHP 540

Query: 555  PADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRA 614
               VQLFQEVPKGQSEEDMVGRPL HL A  QA+GEAVYCDDIP Y NEL LRLVTST+A
Sbjct: 541  ATSVQLFQEVPKGQSEEDMVGRPLAHLTAARQATGEAVYCDDIPLYSNELYLRLVTSTKA 600

Query: 615  HAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKVTCVGHIIGAVVAD 674
            HA+IKSID SEA+KVPGFV F+S  DVPGSNITG+  DETVFA  +VTCVGHIIGAV+AD
Sbjct: 601  HARIKSIDASEAQKVPGFVHFLSVADVPGSNITGLEKDETVFADGEVTCVGHIIGAVLAD 660

Query: 675  TPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPEL--KIEKGDLKKGFSEADNVVS 732
            TPEH QRAAQ VKITYEELPAII+IEDAIKN SF+       +EKGDL+KGF+EAD+++ 
Sbjct: 661  TPEHAQRAAQAVKITYEELPAIISIEDAIKNKSFHKTSFLSTMEKGDLQKGFAEADHILE 720

Query: 733  GEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRV 792
            GE+++GGQEHFYLETH  IA+PKGE GEMELFV+TQ  M  Q F+AK LGVP+NRI VRV
Sbjct: 721  GEVHVGGQEHFYLETHSCIAIPKGEEGEMELFVATQCPMIIQDFIAKALGVPSNRIAVRV 780

Query: 793  KRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFM 852
            KR+GGGFGGK+ R+ ++ST VA+ A+KTGRPVRCMLDR+EDML+TGGRHPF+ARYKVGFM
Sbjct: 781  KRLGGGFGGKDPRTALLSTVVAVGAHKTGRPVRCMLDRNEDMLVTGGRHPFMARYKVGFM 840

Query: 853  KTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAF 912
            K G VVALEVDH+SN GN+ + S+S+M++AL+HMDNCYKIPN+RGTG+LCKTNLPSNTAF
Sbjct: 841  KDGRVVALEVDHYSNSGNSLEFSESVMQKALYHMDNCYKIPNLRGTGKLCKTNLPSNTAF 900

Query: 913  RGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEEC 972
            RGFG PQ MLI E WMS+VAV CG P EEVRR N+Y++GDLTHFNQKLEGFTL RCW EC
Sbjct: 901  RGFGAPQVMLITESWMSQVAVKCGRPPEEVRRLNMYEDGDLTHFNQKLEGFTLSRCWSEC 960

Query: 973  LASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQ 1017
            L SSQYHAR+ E++KFN+EN WKKRGL IIP KFG  F   FLNQ
Sbjct: 961  LESSQYHARRREIEKFNRENYWKKRGLAIIPIKFGPGFDPSFLNQ 1005
>ref|XP_001606854.1| PREDICTED: similar to aldehyde oxidase [Nasonia vitripennis]
          Length = 1355

 Score = 1476 bits (3820), Expect = 0.0,   Method: Composition-based stats.
 Identities = 720/1347 (53%), Positives = 938/1347 (69%), Gaps = 39/1347 (2%)

Query: 6    LVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNKI 65
            L+F+VNG+ + + N +PE TL+ YLR KLGL GTKLGC EG CGACTVM+S++DR  NKI
Sbjct: 25   LIFYVNGKMIKDCNIEPEWTLIYYLRNKLGLCGTKLGCSEGNCGACTVMISRFDRKNNKI 84

Query: 66   VHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMY 125
            +H +ANACL P+C++H +AVTTVEGIGST+ +LHPVQER+AK+HGSQCGFCTPGIVMSMY
Sbjct: 85   IHLAANACLTPVCAMHGMAVTTVEGIGSTRNKLHPVQERLAKAHGSQCGFCTPGIVMSMY 144

Query: 126  TLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGG--------------CCG 171
             LLR+ P+PTM +I+ AFQGNLCRCTGYRPI++G RTF ++                C  
Sbjct: 145  ALLRSNPKPTMNDIDIAFQGNLCRCTGYRPIIEGLRTFTKEWEQSRMSKLKNHEEKLCAL 204

Query: 172  GDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEG 231
            G+     CC    K    S   +LF  +EFTP D +QEPIFPP L    +   + L   G
Sbjct: 205  GNA----CC----KKAFTSEPTALFDSKEFTPYDSSQEPIFPPSLQLSSNLDDEYLIISG 256

Query: 232  ERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVE 291
            + VTW + + LK+LL LK Q+P+AK++VGNTE+G+E+K K++++P+++    I EL  +E
Sbjct: 257  KEVTWYRPTQLKKLLILKNQYPNAKIIVGNTEVGVEVKIKHLMYPVLIQSTAIKELKIIE 316

Query: 292  HGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGN 351
               DGI  GA+  L  +E  L   ++     +T +F  +++ L WFAG Q+++VA+VGGN
Sbjct: 317  EMNDGIKIGASVTLVEMESALRHQISTKHESRTRIFGSIVKMLHWFAGHQIRNVAAVGGN 376

Query: 352  IITASPISDLNPVFMASGAKLTLVS-RGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIP 410
            I+T SPISDLNP+F+A G KL L S     R+V MD+TFF GYR+ +++P+E+LLSIE+P
Sbjct: 377  IMTGSPISDLNPIFLAVGIKLNLCSLNNGHRSVIMDNTFFLGYRRNIVAPDEVLLSIEVP 436

Query: 411  YSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTT 470
            ++   +YF ++KQ+ RR+DDI  V   M V FKP T  VQ++ L +GGMA  T+ A KT 
Sbjct: 437  FNTPNQYFVSYKQSKRRDDDITIVNMAMNVFFKPNTNIVQKINLTFGGMAPITVLAKKTC 496

Query: 471  QRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQE 530
            +  + K W E +L+ V   L  EL LP +APGGM+ +R +LTLS FFK ++++ +KL ++
Sbjct: 497  ESLVGKNWDESILEAVTNNLVAELTLPGNAPGGMILYRRSLTLSLFFKGFISIWKKLHKD 556

Query: 531  --NLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQAS 588
              N+     +L+    SA+  F   PP   Q +Q V K QS  D++GRPL H +A  QAS
Sbjct: 557  IPNIAPVLKELE----SASDGFHYLPPKSSQYYQMVSKDQSSIDLIGRPLIHASAFKQAS 612

Query: 589  GEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSN--I 646
            GEA+YCDDIPR   EL L LV STRAHA+I  ID S+A  + G V +  A D+P     +
Sbjct: 613  GEAIYCDDIPRITGELYLALVLSTRAHARITGIDNSKAVALDGVVAYFDAKDIPEHRRFV 672

Query: 647  TGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIEDAIKN 705
              I  DE VF  +KVTC G +I A+VA      Q+AA+ VKI YEEL P ++TIEDAI+ 
Sbjct: 673  GPIIKDEEVFVSEKVTCHGQVIAAIVAVDQVTAQKAARMVKIDYEELQPVLLTIEDAIEA 732

Query: 706  NSFYGPELK-IEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELF 764
             SF   + + I KG++ + F+  D+++ GEI +GGQEHFYLET C+IA+PK E  EME+ 
Sbjct: 733  KSFLEKDGRSITKGNVDEAFTNVDHILEGEIRMGGQEHFYLETQCSIAIPK-EEHEMEII 791

Query: 765  VSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPV 824
             STQ+  + Q  +A +L +P NR+ VR KR+GGGFGGKE+RS + +  VA AA+   +PV
Sbjct: 792  ASTQDLAEMQRLIAHVLDIPINRVTVRTKRLGGGFGGKESRSMLAALPVAFAAHSLQKPV 851

Query: 825  RCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALF 884
            RCMLDRDEDM+ITG RHPFL +YKVGF   G +  LEV  ++NVG + DLS   + R + 
Sbjct: 852  RCMLDRDEDMMITGTRHPFLFKYKVGFSNEGLIKVLEVYVYANVGCSWDLSGPAISRTMA 911

Query: 885  HMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRR 944
            H++N Y+IP IR  G LCKTNLPSNTAFRGFGGPQGM  AE  +  +A        ++  
Sbjct: 912  HIENAYRIPAIRVIGYLCKTNLPSNTAFRGFGGPQGMFCAETIIRHIADYLDRDVVQLSE 971

Query: 945  KNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPT 1004
             NLYKEGD+TH+NQKLE  T+ RCW ECLA S Y  R + V KFN EN +KK+G+ +IPT
Sbjct: 972  INLYKEGDITHYNQKLENCTMQRCWIECLAFSNYEQRLAAVQKFNSENRYKKKGITVIPT 1031

Query: 1005 KFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYI 1064
            KFGI+F   FLNQ GAL+H+YTDGSVLLTHGG EMGQG+HTKM+QVASR LK+   KI I
Sbjct: 1032 KFGIAFETLFLNQGGALVHIYTDGSVLLTHGGIEMGQGVHTKMIQVASRILKVHPDKILI 1091

Query: 1065 SETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMD 1124
            +ET+T+ VPN + TAAS  +DLNG A+  AC  I+KR++     NP G+WE W+  AY D
Sbjct: 1092 TETATDKVPNATATAASTGSDLNGMAIMDACNKIMKRIKYIIDANPEGTWESWIEKAYFD 1151

Query: 1125 TVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVG 1184
             VSLSATGFYRTP++GY F TNSG  + YF+YGVACSEV ID LTGDH+ LRTDIVMD+G
Sbjct: 1152 RVSLSATGFYRTPDIGYDFATNSGTLYDYFTYGVACSEVIIDSLTGDHQVLRTDIVMDLG 1211

Query: 1185 SSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSL 1244
             SLNPAIDIGQVEG F+QG GLFT+EE+ YSP G +++RGP  YKIP F  IP EF VSL
Sbjct: 1212 ESLNPAIDIGQVEGGFIQGYGLFTMEEMIYSPTGIVYSRGPGVYKIPGFADIPQEFNVSL 1271

Query: 1245 LRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPE 1304
            L+   N +A+Y+SKA+GEPPLFL++SIFFAIK+AI+AAR      N+   FR DSPAT  
Sbjct: 1272 LKGSSNPRAVYSSKAIGEPPLFLSSSIFFAIKNAIKAARKDM---NLHGYFRFDSPATAA 1328

Query: 1305 KIRNACVDKFTTLCVTGVPENCKPWSV 1331
            +IR AC D FT     G  +  KPW++
Sbjct: 1329 RIRMACTDDFTKKIGDG--DGKKPWNI 1353
>pdb|1FIQ|C Chain C, Crystal Structure Of Xanthine Oxidase From Bovine Milk
 pdb|3B9J|C Chain C, Structure Of Xanthine Oxidase With 2-Hydroxy-6-Methylpurine
 pdb|3B9J|K Chain K, Structure Of Xanthine Oxidase With 2-Hydroxy-6-Methylpurine
          Length = 763

 Score = 1474 bits (3815), Expect = 0.0,   Method: Composition-based stats.
 Identities = 688/763 (90%), Positives = 723/763 (94%)

Query: 571  EDMVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVP 630
            ED VGRPLPHLAA MQASGEAVYCDDIPRYENEL LRLVTSTRAHAKIKSID SEA+KVP
Sbjct: 1    EDTVGRPLPHLAAAMQASGEAVYCDDIPRYENELFLRLVTSTRAHAKIKSIDVSEAQKVP 60

Query: 631  GFVCFISADDVPGSNITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITY 690
            GFVCF+SADD+PGSN TG+ NDETVFAKD VTCVGHIIGAVVADTPEH +RAA  VK+TY
Sbjct: 61   GFVCFLSADDIPGSNETGLFNDETVFAKDTVTCVGHIIGAVVADTPEHAERAAHVVKVTY 120

Query: 691  EELPAIITIEDAIKNNSFYGPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCT 750
            E+LPAIITIEDAIKNNSFYG ELKIEKGDLKKGFSEADNVVSGE+YIGGQ+HFYLETHCT
Sbjct: 121  EDLPAIITIEDAIKNNSFYGSELKIEKGDLKKGFSEADNVVSGELYIGGQDHFYLETHCT 180

Query: 751  IAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVS 810
            IA+PKGE GEMELFVSTQN MKTQSFVAKMLGVP NRI+VRVKRMGGGFGGKETRST+VS
Sbjct: 181  IAIPKGEEGEMELFVSTQNAMKTQSFVAKMLGVPVNRILVRVKRMGGGFGGKETRSTLVS 240

Query: 811  TAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGN 870
             AVALAAYKTG PVRCMLDR+EDMLITGGRHPFLARYKVGFMKTGT+VALEVDH+SN GN
Sbjct: 241  VAVALAAYKTGHPVRCMLDRNEDMLITGGRHPFLARYKVGFMKTGTIVALEVDHYSNAGN 300

Query: 871  TQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSE 930
            ++DLS SIMERALFHMDNCYKIPNIRGTGRLCKTNL SNTAFRGFGGPQ + IAE WMSE
Sbjct: 301  SRDLSHSIMERALFHMDNCYKIPNIRGTGRLCKTNLSSNTAFRGFGGPQALFIAENWMSE 360

Query: 931  VAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNK 990
            VAVTCG+PAEEVR KN+YKEGDLTHFNQ+LEGF++PRCW+ECL SSQY+ARKSEVDKFNK
Sbjct: 361  VAVTCGLPAEEVRWKNMYKEGDLTHFNQRLEGFSVPRCWDECLKSSQYYARKSEVDKFNK 420

Query: 991  ENCWKKRGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQV 1050
            ENCWKKRGLCIIPTKFGISFTVPFLNQAGAL+HVYTDGSVL++HGGTEMGQGLHTKMVQV
Sbjct: 421  ENCWKKRGLCIIPTKFGISFTVPFLNQAGALIHVYTDGSVLVSHGGTEMGQGLHTKMVQV 480

Query: 1051 ASRALKIPTSKIYISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNP 1110
            AS+ALKIP SKIYISETSTNTVPN+SPTAASVS D+ GQAVY ACQTILKRLEP+KKKNP
Sbjct: 481  ASKALKIPISKIYISETSTNTVPNSSPTAASVSTDIYGQAVYEACQTILKRLEPFKKKNP 540

Query: 1111 SGSWEDWVTAAYMDTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTG 1170
             GSWEDWV AAY D VSLS TGFYRTPNLGYSFETNSGN FHYF+YGVACSEVEIDCLTG
Sbjct: 541  DGSWEDWVMAAYQDRVSLSTTGFYRTPNLGYSFETNSGNAFHYFTYGVACSEVEIDCLTG 600

Query: 1171 DHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKI 1230
            DHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKI
Sbjct: 601  DHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKI 660

Query: 1231 PAFGSIPIEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNN 1290
            PAFGSIP EFRVSLLRDCPNKKAIYASKAVGEPPLFL AS+FFAIKDAIRAARAQHT NN
Sbjct: 661  PAFGSIPTEFRVSLLRDCPNKKAIYASKAVGEPPLFLGASVFFAIKDAIRAARAQHTNNN 720

Query: 1291 VKELFRLDSPATPEKIRNACVDKFTTLCVTGVPENCKPWSVRV 1333
             KELFRLDSPATPEKIRNACVDKFTTLCVTG P NCKPWS+RV
Sbjct: 721  TKELFRLDSPATPEKIRNACVDKFTTLCVTGAPGNCKPWSLRV 763
>ref|XP_001662131.1| aldehyde oxidase [Aedes aegypti]
 gb|EAT46105.1| aldehyde oxidase [Aedes aegypti]
          Length = 1348

 Score = 1471 bits (3808), Expect = 0.0,   Method: Composition-based stats.
 Identities = 728/1342 (54%), Positives = 945/1342 (70%), Gaps = 31/1342 (2%)

Query: 6    LVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNKI 65
            LVFFVNG+KVVE N DP  TLL YLR KL L GTKLGC EGGCGACTVM+S+ DR  N+I
Sbjct: 20   LVFFVNGKKVVEPNPDPVCTLLVYLRDKLRLCGTKLGCAEGGCGACTVMVSRIDRSTNRI 79

Query: 66   VHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMY 125
             + +ANACL P+C++H +AVTTVEGIGST+TRLHPVQER+AK+HGSQCGFCTPGIVMSMY
Sbjct: 80   HNLAANACLTPVCAVHGMAVTTVEGIGSTRTRLHPVQERLAKAHGSQCGFCTPGIVMSMY 139

Query: 126  TLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTF------ARDGGCCGGDGNNPNC 179
             LLR+ P P+M+E+E AFQGNLCRCTGYRPI++G++TF      A++G C  GD     C
Sbjct: 140  ALLRSSPVPSMKEMEVAFQGNLCRCTGYRPIIEGYKTFTQEFGNAQNGVCAMGD----KC 195

Query: 180  CMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQA 239
            C N      V +   LF   EF P DP+QEPIFPPEL          L F+     W + 
Sbjct: 196  CKNSSNGCGVEVDDKLFDASEFAPFDPSQEPIFPPELKLSDSLDADSLVFQSGTTRWYRP 255

Query: 240  STLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISF 299
            + L  LL +K ++PDAKL+VGNTE+G+E+KFKNM +P++V P  I EL  VE    G+  
Sbjct: 256  TKLDHLLLIKKRYPDAKLIVGNTEVGVEVKFKNMEYPVLVYPTQIKELTGVEKLERGLKV 315

Query: 300  GAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPIS 359
            G++  L  +E+ L + ++ LP  ++ ++R +++ L WFAGKQ++++ASVGGNI+T SPIS
Sbjct: 316  GSSVTLVEMERVLREEISALPECESRLYRAIVDMLHWFAGKQIRNMASVGGNIMTGSPIS 375

Query: 360  DLNPVFMASGAKLTLVS-RGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYF 418
            DLNP+F A+G +L + S  G  R V M   FF GYR+ ++ PEEIL+S+ IP +   ++F
Sbjct: 376  DLNPIFTAAGIELEVASLDGGVRKVHMGDGFFTGYRRNIIRPEEILVSLFIPKTNSDQHF 435

Query: 419  SAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLW 478
             A+KQA RR+DDIA V     + FKPGT  V +  L +GGMA  T+ A +T +  + K W
Sbjct: 436  IAYKQAKRRDDDIAIVNGAFNITFKPGTDIVAQAHLSFGGMAPTTVLAKRTGEALVGKKW 495

Query: 479  KEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQ-----ENLE 533
               L++     + EEL L P APGGM+ +R +LTLS FFK YL++   L +     E +E
Sbjct: 496  DSTLVELANDMMVEELPLSPSAPGGMILYRRSLTLSLFFKAYLSISDVLSRTVANHEPVE 555

Query: 534  DKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVY 593
            D+      TF   TL+     P   QLF++V   Q   D + RP  H +A  Q +GEA+Y
Sbjct: 556  DRERSGAETFH--TLI-----PKSAQLFEKVSSDQPNHDPIRRPKVHASAFKQVTGEAIY 608

Query: 594  CDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVP-GSNITG-ICN 651
            CDDIP+Y NEL L LVTST+AHAKI SID+SEA  + G   F +A D+    N  G + +
Sbjct: 609  CDDIPKYSNELYLTLVTSTKAHAKIISIDSSEALAMEGVHQFFTAADLTEDQNACGPVFH 668

Query: 652  DETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIEDAIKNNSFY- 709
            DE VF  + VT  G IIGA+VAD+   +Q+AA+ VK+TYE+L P I+T+EDAIK  SFY 
Sbjct: 669  DEFVFWNNLVTSQGQIIGAIVADSQAISQKAARKVKVTYEDLTPIIVTLEDAIKKESFYP 728

Query: 710  GPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQN 769
            G    I +GD++KGF +A +++ G+  +GGQEHFYLET   +AVPK ++ E+E+F S+Q+
Sbjct: 729  GYPKSIIQGDIEKGFQQAKHIIEGDCRMGGQEHFYLETQACVAVPK-DSDEIEVFTSSQH 787

Query: 770  TMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLD 829
              + Q  VA  LG+P+ ++V RVKR+GGGFGGKE+R+ +V+  VALAAY+  RPVRCMLD
Sbjct: 788  PSEIQQHVAHALGIPSCKVVSRVKRLGGGFGGKESRAALVAIPVALAAYRLRRPVRCMLD 847

Query: 830  RDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNC 889
            RDEDM ITG RHPF   YKVG  + G V+A +   ++N G + DLS SI+ER++FH+ N 
Sbjct: 848  RDEDMQITGTRHPFYFTYKVGVDEHGKVLAADFKAYNNAGYSMDLSFSILERSMFHIQNA 907

Query: 890  YKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYK 949
            YKIPN+R  G +CKTNLPSNTAFRGFGGPQGML  E  M  VA        E+   N+Y+
Sbjct: 908  YKIPNLRVQGWVCKTNLPSNTAFRGFGGPQGMLAGETMMRHVARVLNRDYVELAELNMYQ 967

Query: 950  EGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGIS 1009
            EGD TH+N+ +E   + RCW+E + SS +  R++ +++FN E+ W+KRG+ ++PT FGI+
Sbjct: 968  EGDKTHYNELIENCNVRRCWQEMIVSSDFKDRRAMIERFNTEHRWRKRGISVVPTMFGIA 1027

Query: 1010 FTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETST 1069
            FT   LNQ+GAL+HVY DG++LL+HGG EMGQGLHTKM+QVA+  LK+P   I+ISETST
Sbjct: 1028 FTAVHLNQSGALIHVYQDGAILLSHGGIEMGQGLHTKMIQVAATTLKVPFETIHISETST 1087

Query: 1070 NTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLS 1129
            + VPNT  TAAS  +DLNG AV  AC+ I +RLEPYKK+ P   W+ WV  AY D VSLS
Sbjct: 1088 DKVPNTPATAASAGSDLNGMAVMNACKIINERLEPYKKQYPDKDWKFWVNKAYFDRVSLS 1147

Query: 1130 ATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNP 1189
            ATGFY TPN+GY F TNSGNPF+YF++G ACSEVEIDCLTGDH+ +RTDIVMD+GSS+NP
Sbjct: 1148 ATGFYATPNIGYDFATNSGNPFNYFTFGAACSEVEIDCLTGDHQVIRTDIVMDLGSSINP 1207

Query: 1190 AIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCP 1249
            AIDIGQ+EG F+QG GLFTLEE+ YSP G+ ++RGP  YKIP F  IP EF VSLL   P
Sbjct: 1208 AIDIGQIEGGFMQGYGLFTLEEMVYSPTGTTYSRGPGVYKIPGFADIPGEFNVSLLTGAP 1267

Query: 1250 NKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNA 1309
            N +A+Y+SKAVGEPPLFLA+S FFAI++AI AARA+ +   + + F L SPAT  +IR A
Sbjct: 1268 NPRAVYSSKAVGEPPLFLASSTFFAIRNAISAARAEES---LDDDFNLVSPATSSRIRMA 1324

Query: 1310 CVDKFTTLCVTGVPENCKPWSV 1331
            C DKFT   V   P +  PW+V
Sbjct: 1325 CQDKFTKKFVESTPSSFTPWNV 1346
>ref|XP_001846124.1| xanthine dehydrogenase [Culex pipiens quinquefasciatus]
 gb|EDS42575.1| xanthine dehydrogenase [Culex pipiens quinquefasciatus]
          Length = 1329

 Score = 1464 bits (3789), Expect = 0.0,   Method: Composition-based stats.
 Identities = 721/1342 (53%), Positives = 943/1342 (70%), Gaps = 31/1342 (2%)

Query: 6    LVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQN-- 63
            +++    + V+E N DPE TLL YLR KL L GTKLGC EGGCGACTVM+S+ DR     
Sbjct: 1    MLWIQRSQAVIEPNPDPECTLLVYLRDKLRLCGTKLGCAEGGCGACTVMISRIDRTAGTC 60

Query: 64   -KIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVM 122
             ++ + +ANACL P+CS+H +AVTTVEGIGST+TRLHPVQER+AK+HGSQCGFCTPGIVM
Sbjct: 61   GRVHNLAANACLTPVCSVHGMAVTTVEGIGSTRTRLHPVQERLAKAHGSQCGFCTPGIVM 120

Query: 123  SMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMN 182
            SMY LLRN   P+M+E+E AFQGNLCRCTGYRPIL+G++TF ++ GC  GD     CC N
Sbjct: 121  SMYALLRNSAVPSMKELEVAFQGNLCRCTGYRPILEGYKTFTKEFGCAMGD----KCCKN 176

Query: 183  QKKDHS---VSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQA 239
            Q    +   V +   LF   EF P DPTQEPIFPPEL        + L F   +  W + 
Sbjct: 177  QNGTSNGCGVEVDDKLFDVSEFKPFDPTQEPIFPPELKLSDSLDVESLVFRSSKTCWYRP 236

Query: 240  STLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISF 299
            + L  LL LK +HPDAK++VGNTE+G+E+KFK+  +P++V P  I EL  +E    G+  
Sbjct: 237  TKLDHLLTLKKKHPDAKIIVGNTEVGVEVKFKHFEYPVLVYPTQIAELTQLERVDGGLKV 296

Query: 300  GAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPIS 359
            G++  L  +E+ + + + KLP  +T ++R +++ L +FAGKQ++++ASVGGNI+T SPIS
Sbjct: 297  GSSVTLVEMERVMREEIDKLPESETRLYRAIVDMLHYFAGKQIRNMASVGGNIMTGSPIS 356

Query: 360  DLNPVFMASGAKLTLVS-RGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYF 418
            DLNP+F A+  +L + S  G  R V+M   FF GYRK ++ P+E+L+S+ IP + +  +F
Sbjct: 357  DLNPIFTAAAIELEVASLDGGVRKVRMGDGFFTGYRKNVIRPDEVLVSLFIPKTNQDLHF 416

Query: 419  SAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLW 478
             A+KQA RR+DDIA V    +VLFK GT  V+++ L +GGMA  T+ A KT    + + W
Sbjct: 417  IAYKQAKRRDDDIAIVNGAFQVLFKQGTDIVEQIHLAFGGMAPTTVLAKKTAAALVGQKW 476

Query: 479  KEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQ-----ENLE 533
             + L++     + EEL L P APGGM+ +R +LTLS FFK YL + + LG+     E ++
Sbjct: 477  DKALVEKANDLMVEELPLSPSAPGGMIPYRRSLTLSLFFKAYLAISEVLGKTVTGREPIQ 536

Query: 534  DKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVY 593
            D+      TF +         P   QLF++V   Q   D + RP  H +A  Q +GEAVY
Sbjct: 537  DREKSGANTFHTLV-------PKSAQLFEKVANDQPITDPIRRPQVHASAFKQVTGEAVY 589

Query: 594  CDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDV--PGSNITGICN 651
            CDDIP+Y NEL L LV S++AHAK+ SID +EA  + G   F SADD+   G+    + +
Sbjct: 590  CDDIPKYSNELYLALVISSKAHAKVLSIDPTEALAMEGVHRFFSADDLCSEGNTCGPVFH 649

Query: 652  DETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIEDAIKNNSFY- 709
            DE VF KD VT  G ++GA+VA+     Q+AA+ VKI YEEL P I+TIEDAI   S+Y 
Sbjct: 650  DEFVFWKDVVTSQGQLLGAIVAENQSIAQKAARKVKIAYEELTPVIVTIEDAIAKGSYYP 709

Query: 710  GPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQN 769
            G    I +GD+++GF +A  +V G+  +GGQEHFYLET   +AVPK ++ E+E+F S+Q+
Sbjct: 710  GYPKSIVQGDIEQGFKQAYKIVEGDCRLGGQEHFYLETQACVAVPK-DSDEIEVFSSSQH 768

Query: 770  TMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLD 829
              + Q  VAK LG+P+ ++V RVKR+GGGFGGKE+R+ +++  VALAAYK  RPVRCMLD
Sbjct: 769  PTEVQQHVAKALGIPSCKVVSRVKRLGGGFGGKESRAAMLAVPVALAAYKLQRPVRCMLD 828

Query: 830  RDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNC 889
            RDEDM ITG RHPF   YKVG  K G ++A +   ++N G + DLS S++ERA+FH+ N 
Sbjct: 829  RDEDMAITGTRHPFYFTYKVGVDKDGRLLAADFKAYNNAGYSMDLSFSVLERAMFHIQNS 888

Query: 890  YKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYK 949
            YK+PN+R  G +CKTNLPSNTAFRGFGGPQGML AE  M  VA   G    E+   NLYK
Sbjct: 889  YKVPNLRVQGWVCKTNLPSNTAFRGFGGPQGMLAAETMMHHVARALGRDYVELVELNLYK 948

Query: 950  EGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGIS 1009
            EGD TH+N+ +E   + +CWEE + SS++  R++EV++FNK+N W+KRG+ ++PT FGI+
Sbjct: 949  EGDKTHYNEPIENCNVKKCWEEVIKSSRFQERRAEVEQFNKQNRWRKRGISLVPTTFGIA 1008

Query: 1010 FTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETST 1069
            FT   LNQ+GAL+HVY+DG+VLL+HGGTEMGQGLHTKM+QVA+  LK+P  KI+ISETST
Sbjct: 1009 FTAVHLNQSGALIHVYSDGAVLLSHGGTEMGQGLHTKMIQVAATTLKVPFEKIHISETST 1068

Query: 1070 NTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLS 1129
            + VPNTSPTAAS  +DLNG AV  AC+ I +RLEPYKK+ P   W  WV  AY D VSLS
Sbjct: 1069 DKVPNTSPTAASAGSDLNGMAVLNACKVINERLEPYKKQFPDKDWNFWVNKAYFDRVSLS 1128

Query: 1130 ATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNP 1189
            ATGFY TP +GY F TNSGNPF+YF++G + SEVEIDCLTGDH+ +RTDIVMD+GSSLNP
Sbjct: 1129 ATGFYATPGIGYDFGTNSGNPFNYFTFGASVSEVEIDCLTGDHQVIRTDIVMDLGSSLNP 1188

Query: 1190 AIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCP 1249
            AIDIGQ+EG F+QG GLFTLEE+ YSP G++++RGP  YKIP F  IP EF VSLL   P
Sbjct: 1189 AIDIGQIEGGFMQGYGLFTLEEMVYSPTGTVYSRGPGVYKIPGFADIPGEFNVSLLTGAP 1248

Query: 1250 NKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNA 1309
            N +A+Y+SKAVGEPP+FLA+S FFAI++AI AAR +    N+ + F L SPAT  +IR A
Sbjct: 1249 NPRAVYSSKAVGEPPVFLASSTFFAIREAISAARKEE---NLDDDFNLVSPATSSRIRMA 1305

Query: 1310 CVDKFTTLCVTGVPENCKPWSV 1331
            C D  T   V   PE   PW+V
Sbjct: 1306 CQDSITKKFVEAAPETITPWNV 1327
>dbj|BAA21640.1| xanthine dehydrogenase [Bombyx mori]
          Length = 1356

 Score = 1458 bits (3774), Expect = 0.0,   Method: Composition-based stats.
 Identities = 718/1349 (53%), Positives = 943/1349 (69%), Gaps = 32/1349 (2%)

Query: 5    KLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNK 64
            +LVF+VNG+KV+E + DPE TLL YLR+KL L+GTKLGC EGGCGACTVM+SKY+R +NK
Sbjct: 16   ELVFYVNGKKVIESSPDPEWTLLWYLRKKLRLTGTKLGCAEGGCGACTVMVSKYNRQENK 75

Query: 65   IVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSM 124
            I+H + NACLAP+C++H +AVTTVEGIGSTKT+LHPVQERIAK+HGSQCGFCTPGIVMSM
Sbjct: 76   IIHLAVNACLAPVCAMHGLAVTTVEGIGSTKTKLHPVQERIAKAHGSQCGFCTPGIVMSM 135

Query: 125  YTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARD-------------GGCCG 171
            YTLLR+       ++E AFQGNLCRCTGYR I++G++TF  D             G C  
Sbjct: 136  YTLLRSCKNIQYSDLEVAFQGNLCRCTGYRAIIEGYKTFIEDWETQRIVKNGPQNGTCAM 195

Query: 172  GDGNNPNCCMNQKK--DHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRF 229
            G     +CC N+    + + S S  +F    F P D +QEPIFPPEL        + + +
Sbjct: 196  GK----DCCKNKSDSCEEADSESQYIFDKSSFLPYDSSQEPIFPPELKLSSIYDSQYVIY 251

Query: 230  EGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNS 289
             G++ TW + + ++ +L LK + P+AK+VVGN+E+G+E+KFK  ++P+I+ P  +PELN+
Sbjct: 252  RGKQTTWYRPTNIETVLSLKDKFPNAKVVVGNSEVGVEVKFKRCVYPIIIMPNCVPELNT 311

Query: 290  VEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVG 349
            +     G++ GA+  L+ +EKT  + + KLP  KT V   ++E L WFAGKQ+++VA++G
Sbjct: 312  ITENEHGLTVGASVTLNDIEKTFREYIKKLPPYKTRVLTTIVEMLNWFAGKQIRNVAAIG 371

Query: 350  GNIITASPISDLNPVFMASGAKLTLVSR-GTRRTVQMDHTFFPGYRKTLLSPEEILLSIE 408
            GN++T SPISDLNP+ M+   KL L+S+    RTV MD TFF GYRK ++   EILLSIE
Sbjct: 372  GNVMTGSPISDLNPILMSLKVKLNLLSQENGHRTVLMDETFFTGYRKNVVKSNEILLSIE 431

Query: 409  IPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALK 468
            IP+S + +Y  A KQA RREDDI+ VTS + V F+  T  ++ + L +GGMA  T  A  
Sbjct: 432  IPFSTKFQYLKAIKQAKRREDDISIVTSAVNVEFEENTNVIKYINLAFGGMAPVTKIATN 491

Query: 469  TTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLG 528
            T        W E +L+   + L +EL L P APGG + FR  LT+S F K YL + + + 
Sbjct: 492  TGNVLKGLKWNENMLEKAYSLLIDELPLDPSAPGGNIQFRRALTMSLFLKSYLAIGKAMS 551

Query: 529  QENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQAS 588
             +        ++  + S    F  + P   Q F+ V + Q + D VGRP+ H++A  QA+
Sbjct: 552  TDYFYGDL--IESYYGSGADSFHGNVPKSSQYFELVGEKQHKSDAVGRPIQHMSAYKQAT 609

Query: 589  GEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVP--GSNI 646
            GEA+YCDD+P  E EL L  V S++AHAK+ S+D  +A   PG + F SA D+    ++I
Sbjct: 610  GEAIYCDDMPIAEGELYLAFVLSSKAHAKLVSVDAKKALAEPGVIAFYSAKDLTEEQNSI 669

Query: 647  TGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIEDAIKN 705
              I +DE +FA+DKV   G  IG +VA      Q AA+ VK+ YEE+ P I+TIEDAIK 
Sbjct: 670  GPIFHDEELFARDKVLSQGQTIGVIVAVDQATAQAAARMVKVEYEEIQPIIVTIEDAIKY 729

Query: 706  NSFYGPEL--KIEKGDLKKGFSEADNVV-SGEIYIGGQEHFYLETHCTIAVPKGEAGEME 762
            NSFY P+    I++G++K  F + +N++  G+  +GGQEHFYLETH   A+PK E  E+E
Sbjct: 730  NSFY-PQFPKTIKRGNVKAVFDDKNNIIIEGQCRMGGQEHFYLETHAAFAIPKKEDDELE 788

Query: 763  LFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGR 822
            +F S+Q+  +    V+ +L VP NRIV RVKRMGGGFGGKE+R  +V+  VALAA+K  R
Sbjct: 789  IFCSSQHPSEIAKLVSHILHVPMNRIVARVKRMGGGFGGKESRGMLVALPVALAAHKLNR 848

Query: 823  PVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERA 882
            PVRCMLDRDEDM +TG RHPFL +YK    K G +V   V+ ++N G + DLS  ++ERA
Sbjct: 849  PVRCMLDRDEDMQMTGTRHPFLIKYKAAATKEGKIVGAVVNIYNNGGYSTDLSGPVVERA 908

Query: 883  LFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEV 942
            +FH +N Y IPN   TG +C+TNLPSNTAFRGFGGPQGM  AE  + E+A   G   EE+
Sbjct: 909  MFHFENAYYIPNCEVTGYVCRTNLPSNTAFRGFGGPQGMFGAENMVREIAHRLGKSPEEI 968

Query: 943  RRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCII 1002
             R NLY+E + TH+ Q L   TL RCW+EC+ +S    RK ++ +FNK++ W+KRG+ II
Sbjct: 969  SRLNLYRENNTTHYGQVLTYCTLQRCWDECVQNSNLAERKLKIKEFNKQHRWRKRGISII 1028

Query: 1003 PTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI 1062
            PTKFGI+FT   LNQAGAL+ VY DGSVLL+HGGTEMGQGLHTKM+QVA+RAL I  SKI
Sbjct: 1029 PTKFGIAFTEKLLNQAGALVLVYVDGSVLLSHGGTEMGQGLHTKMIQVATRALGIDVSKI 1088

Query: 1063 YISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAY 1122
            +ISETST+ VPNTS TAAS  +DLNG AV  AC+ I+KRL+PY  KNP G WE+WV+AAY
Sbjct: 1089 HISETSTDKVPNTSATAASAGSDLNGMAVLEACEKIMKRLKPYIDKNPDGKWENWVSAAY 1148

Query: 1123 MDTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMD 1182
            +D VSLSATGF+ TP++G+ F+T SG PF+YF+YGVAC+EVEIDCL+GDH+ LRTDIVMD
Sbjct: 1149 VDRVSLSATGFHATPDIGFDFKTTSGKPFNYFTYGVACTEVEIDCLSGDHQVLRTDIVMD 1208

Query: 1183 VGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRV 1242
            +G SLNPAIDIGQ+EG F+QG GLFT+EEL YSP G+L++RGP  YKIP FG IP+EF V
Sbjct: 1209 LGESLNPAIDIGQIEGGFIQGYGLFTIEELIYSPTGTLYSRGPGAYKIPGFGDIPLEFNV 1268

Query: 1243 SLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPAT 1302
            SLL+  PN +A+Y+SKAVGEPPLFLA+S +FAI +AI+AARA      V   F +++PAT
Sbjct: 1269 SLLKGAPNPRAVYSSKAVGEPPLFLASSAYFAIHEAIKAARAD---AGVPLEFDMEAPAT 1325

Query: 1303 PEKIRNACVDKFTTLCVTGVPENCKPWSV 1331
              +IR AC D  T       P +  PW+V
Sbjct: 1326 SARIRMACEDHITKKLDKPDPNSFVPWNV 1354
>emb|CAP08999.1| xanthine dehydrogenase [Lutzomyia longipalpis]
          Length = 1331

 Score = 1457 bits (3771), Expect = 0.0,   Method: Composition-based stats.
 Identities = 714/1335 (53%), Positives = 936/1335 (70%), Gaps = 18/1335 (1%)

Query: 3    ADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQ 62
            +  L+FFVNG+K+VE+  +PE TLL YLR  L L GTKLGC EGGCGACTVM+S+ +R  
Sbjct: 7    SSTLIFFVNGKKIVEEKPNPELTLLTYLRENLRLCGTKLGCAEGGCGACTVMVSRVNRDT 66

Query: 63   NKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVM 122
             ++ H + NACLAP+CS+H +AVTTVEGIGST+TRLHPVQERIAK+HGSQCGFCTPGIVM
Sbjct: 67   KEVQHLAVNACLAPLCSMHGLAVTTVEGIGSTRTRLHPVQERIAKAHGSQCGFCTPGIVM 126

Query: 123  SMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMN 182
            SMY  LR+ P+PTM ++E  FQGNLCRCTGYRPI++GFRTF  DGG   G      CC  
Sbjct: 127  SMYATLRSIPKPTMADLETTFQGNLCRCTGYRPIIEGFRTFTVDGGAQNGCAMGEKCCKV 186

Query: 183  QKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQASTL 242
                     S  LF+P EF P DP+QEPIFPPEL       R+ L F GER++W + +TL
Sbjct: 187  GGNGGCCEESNILFEPSEFIPYDPSQEPIFPPELKCSDILDRQSLIFSGERISWYRPTTL 246

Query: 243  KELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGAA 302
             ELLD+K + P+AK+VVGNTE+G+E+KF+N  FP++V    + ELN +    +G+  GA+
Sbjct: 247  HELLDIKKKFPNAKIVVGNTEVGVEVKFRNCNFPILVSTTEVSELNKISETSEGLKVGAS 306

Query: 303  CPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDLN 362
              LS +E+ L + + K P  +T +F+ ++  L +FAGKQ+++VASVGGNI+  SPISDL 
Sbjct: 307  VALSQMEQKLRELIEKHPEGETRIFKAIISMLHYFAGKQIRNVASVGGNIMHGSPISDLI 366

Query: 363  PVFMASGAKLTLVS-RGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAF 421
            P+F A+  +L ++S  G  R++ MD  FF GYR+ L+  +EIL+++ +P++RE ++F A 
Sbjct: 367  PIFTAAKVELEVMSVSGQNRSIPMDGNFFTGYRRNLIRADEILVALTLPFTREEQHFVAL 426

Query: 422  KQASRREDDIAKVTSGMRVLFKP-GTTEVQELALCYGGMANRTISALKTTQRQLSKLWKE 480
            KQA RR+DDIA V   + V+F+   +T+V+ L L +GGMA   ++A K +     K W +
Sbjct: 427  KQARRRDDDIAIVNIAVNVIFEGMKSTKVKSLDLAFGGMAPTVVTAPKASALAKGKEWNQ 486

Query: 481  ELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLD 540
            +L++ VC  LA EL L   APGGM+ +R +LTLS FFK +L + + L  +  +++    D
Sbjct: 487  DLVEAVCDTLASELPLDSGAPGGMILYRRSLTLSLFFKAFLAISRDLKLDVADEEISGAD 546

Query: 541  PTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRY 600
                     F+   P   Q F++VP GQ   + + RP  H +A  QA+GEAVYCDD+PR+
Sbjct: 547  A--------FKALHPKSTQTFEKVPDGQEPWNPIRRPQVHASAFKQATGEAVYCDDMPRF 598

Query: 601  ENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGS-NITG-ICNDETVFAK 658
            ENEL L  V ST++HAKI SID  EA  +PG V F SA D+P   N+ G + +DE +F  
Sbjct: 599  ENELYLGFVLSTKSHAKIISIDAVEALALPGVVAFYSAKDIPADRNLIGPVFHDEELFVS 658

Query: 659  DKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIEDAIKNNSFY-GPELKIE 716
            + VT    IIG +VAD     QRA++ VKI YE++ P I+T+EDAI++ S++ G    I 
Sbjct: 659  ETVTSQSQIIGVIVADNQSLAQRASKLVKIIYEDINPIIVTLEDAIEHQSYFPGYPKVIR 718

Query: 717  KGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSF 776
            KGD +K   EAD+VV GE+ +GGQEHFYLET  +IAVP+ +  E+ELF STQ+  + Q  
Sbjct: 719  KGDPEKALKEADHVVEGEVRMGGQEHFYLETQASIAVPR-DNDELELFCSTQHPSEIQKL 777

Query: 777  VAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLI 836
            VA  L +PA+++V RVKRMGGGFGGKETR  + +  VA A+YK GRPVRCMLDRDEDM +
Sbjct: 778  VAHTLAIPASKVVTRVKRMGGGFGGKETRGMLTALPVAFASYKLGRPVRCMLDRDEDMKM 837

Query: 837  TGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIR 896
            TG RHPF  +YK G  K G + A+ V  ++N G + DLS SI+ERA++H+ N Y +PN  
Sbjct: 838  TGTRHPFYFKYKAGCTKEGQITAIIVSIYNNAGYSMDLSFSIVERAMYHILNAYYVPNAL 897

Query: 897  GTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHF 956
              G +CKTNLPSNTAFRGFGGPQGM + E  + +VA T      EV   NL + G  TH+
Sbjct: 898  VEGWVCKTNLPSNTAFRGFGGPQGMFVGEHIIRDVARTVHRDYVEVAELNLMRTGLKTHY 957

Query: 957  NQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLN 1016
            NQ++E   + RCW+E ++SS +  R+ +V++FN ++ W+KRG+ I+  +FGISFT  FLN
Sbjct: 958  NQEVELCQVGRCWKELISSSDFQKRRKDVEQFNAQHRWRKRGISIVGVQFGISFTTAFLN 1017

Query: 1017 QAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTS 1076
            Q+GAL+H+YTDGSVLL+HGGTEMGQGLHTKM+QVA+  L +P  +I+ISETST+ VPNTS
Sbjct: 1018 QSGALVHIYTDGSVLLSHGGTEMGQGLHTKMIQVAATTLGVPFERIHISETSTDKVPNTS 1077

Query: 1077 PTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRT 1136
             TAAS  +DLNG AV  AC+ + +RLEPY+K  P   W  WV+ AYMD V LSATGFY T
Sbjct: 1078 ATAASAGSDLNGMAVLEACKVLRERLEPYRKAYPDEGWNKWVSRAYMDRVGLSATGFYAT 1137

Query: 1137 PNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQV 1196
            PN+GY F TNSG PF+YF++G  CSEVEIDCLTGDH+ +RTDIVMD+GSS+NPAIDIGQ+
Sbjct: 1138 PNIGYDFATNSGRPFNYFTFGAGCSEVEIDCLTGDHQVIRTDIVMDLGSSINPAIDIGQI 1197

Query: 1197 EGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYA 1256
            EGAF+QG GLFTLEE+ Y+ +G L +RGP  YK+P F  IP EF VSLL   PN KA+Y+
Sbjct: 1198 EGAFMQGYGLFTLEEMVYAADGMLLSRGPGAYKLPGFADIPGEFNVSLLTGAPNPKAVYS 1257

Query: 1257 SKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTT 1316
            SKAVGEPPLF  AS+FFAIK+AI  AR      N+   F L SPAT  +IR AC DKFT 
Sbjct: 1258 SKAVGEPPLFSGASVFFAIKEAIADARRHE---NLDPDFPLVSPATSARIRMACQDKFTQ 1314

Query: 1317 LCVTGVPENCKPWSV 1331
                  P+  KPW+V
Sbjct: 1315 RFAEADPKTFKPWNV 1329
>ref|XP_001606866.1| PREDICTED: similar to xanthine dehydrogenase [Nasonia vitripennis]
          Length = 1359

 Score = 1450 bits (3753), Expect = 0.0,   Method: Composition-based stats.
 Identities = 713/1336 (53%), Positives = 936/1336 (70%), Gaps = 41/1336 (3%)

Query: 3    ADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQ 62
            ++ LVFFVNG++V +   +PE TLL YLR KL L GTKLGC EGGCGACTVM+S+YDR Q
Sbjct: 30   SNTLVFFVNGKEVRDSRVEPEWTLLYYLRNKLNLYGTKLGCAEGGCGACTVMVSRYDRKQ 89

Query: 63   NKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVM 122
            +KI+H + NACL P+C++H +AVTTVEGIGST+T+LHPVQERIAK+HGSQCGFCTPGIVM
Sbjct: 90   DKIIHVAVNACLTPVCAMHGMAVTTVEGIGSTRTKLHPVQERIAKAHGSQCGFCTPGIVM 149

Query: 123  SMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTF--------------ARDGG 168
            SMY LLR +P P++++IE AFQGNLCRCTGYRPI++G++TF               +D  
Sbjct: 150  SMYALLRTKPLPSIQDIEVAFQGNLCRCTGYRPIIEGYKTFTEEWEKSRLSRNDEGKDRT 209

Query: 169  CCGGDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLR 228
            C  GD     CC    +    S    +F    FTP DP+QE IFPP+L    +   +   
Sbjct: 210  CAMGDA----CC----RRVFTSEPQEVFDTNTFTPYDPSQEIIFPPKLQLSSEFDDEYFI 261

Query: 229  FEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELN 288
             +G+ VTW +   L+E+L LK Q+P++K++VGNTE+G+E+KFK+ ++P+++ P  I EL 
Sbjct: 262  MKGKEVTWYRPIHLREILALKQQYPNSKIIVGNTEVGVEVKFKHFVYPVLIQPIKIKELR 321

Query: 289  SVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASV 348
             +    D I  GA+  L  +E+ L   +   P +KT +F  ++  L WFAGKQ+++VA++
Sbjct: 322  DITELNDAIRIGASVTLIEMEEALRHQIQTKPEEKTRIFDSIVGMLNWFAGKQIRNVAAI 381

Query: 349  GGNIITASPISDLNPVFMASGAKLTLVS--RGTRRTVQMDHTFFPGYRKTLLSPEEILLS 406
            GGNI+T SPISD+NPV MA+G KL + S  RG R ++ MDH+FF GYR+ +++P+E+LLS
Sbjct: 382  GGNIMTGSPISDMNPVLMAAGIKLNVCSLERGVR-SITMDHSFFVGYRRNVVAPDEVLLS 440

Query: 407  IEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISA 466
            IEIPYS   +YF ++KQA RR+DDIA V   + V F+P T+ V +  + +GGMA  TI A
Sbjct: 441  IEIPYSTPNQYFVSYKQAKRRDDDIAIVNLALNVFFEPRTSIVAKSYMAFGGMAPTTILA 500

Query: 467  LKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQK 526
             K+ +  + K W E+L++ V   L  EL L  DAPGGMV +R +LTLS FFK ++ + +K
Sbjct: 501  RKSCEAMIGKKWNEQLVETVTDSLVNELPLSGDAPGGMVLYRRSLTLSLFFKGFVCITKK 560

Query: 527  LGQENLEDKCGKLDP---TFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAA 583
            L           +DP      +A   F    P   Q FQ VPK QS  D++GRP+ H+ A
Sbjct: 561  L-----RISVNDVDPLPKELETAGEGFHFQAPKSSQYFQVVPKDQSSIDLIGRPIIHINA 615

Query: 584  DMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPG 643
              QA+GEA+YCDDIPR   EL L LV ST+AHAKI  ID S+A  + G   F+SA+D+P 
Sbjct: 616  FKQATGEAIYCDDIPRITGELYLALVLSTKAHAKIVKIDPSQALAMEGVEAFLSAEDIPE 675

Query: 644  SN--ITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIE 700
                I   C DE VF    VT  G  +GA++A      Q+A + VK+ YEEL P IITIE
Sbjct: 676  KQRIIGHKCFDEEVFVSKIVTSQGQSLGAILAVDQITAQKAVKLVKVEYEELQPIIITIE 735

Query: 701  DAIKNNSFYGPE-LKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAG 759
            DAIK+ SF+      I  GD+ K F+E+D+V+ GE+ +GGQEHFYLET  ++A  + E G
Sbjct: 736  DAIKHKSFFHERPTVICNGDVDKVFAESDHVIEGEVRMGGQEHFYLETQASLANFR-EEG 794

Query: 760  EMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYK 819
            E+ELF STQN  + Q   A +L +P +RI VRVKR+GGGFGGKETR  +V+  VA+AAYK
Sbjct: 795  ELELFSSTQNPTEIQKLTAHVLNLPISRINVRVKRLGGGFGGKETREALVALPVAIAAYK 854

Query: 820  TGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIM 879
              +PVRCMLDRDEDM+ITG RHPFL +YKVGF K G + A EV  ++N G + DLS +++
Sbjct: 855  YRKPVRCMLDRDEDMMITGTRHPFLIKYKVGFTKDGLITAAEVCLYNNCGYSTDLSPAVL 914

Query: 880  ERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPA 939
            E A+F++ N YK+P  + +G +CKTNLPSNTAFRGFGGPQGM  AE  + ++A   G+  
Sbjct: 915  ECAMFYVLNGYKVPVAKVSGYMCKTNLPSNTAFRGFGGPQGMFCAENIIRQIADYLGLDH 974

Query: 940  EEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGL 999
             ++  KNLY+EGD+T +NQ L   TL RCWEECL SS Y  R +EV++FNKE+ +KKRG+
Sbjct: 975  VKISEKNLYREGDITFYNQPLIKCTLRRCWEECLFSSNYKERVTEVNQFNKEHRYKKRGI 1034

Query: 1000 CIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPT 1059
             ++P  FGI + V FLNQ GAL+HVYTDGSVLL HGG EMGQGL+TKM+Q+ASR LK+  
Sbjct: 1035 AVVPVMFGIGYEVAFLNQGGALVHVYTDGSVLLNHGGVEMGQGLYTKMIQIASRILKVKP 1094

Query: 1060 SKIYISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVT 1119
             KIY +ET T+ VPNT  TAAS+ +DLNG AV  AC  I++R++     +P G+WEDWV 
Sbjct: 1095 DKIYTAETGTDKVPNTIATAASLGSDLNGMAVLDACTKIMERIKYIIDDDPEGTWEDWVK 1154

Query: 1120 AAYMDTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDI 1179
             AY D +SLSATG+YRTP +GY F+TNSG  F+Y++YG AC+EVE+DCLTGDH+ LR+D+
Sbjct: 1155 RAYFDRISLSATGYYRTPEIGYDFDTNSGRRFNYYTYGTACTEVELDCLTGDHEVLRSDV 1214

Query: 1180 VMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIE 1239
            VMD+G SLNPAIDIGQVEG F+QG GLFT+EE+ YSP G + +RGP  YKIP+F +IP E
Sbjct: 1215 VMDLGESLNPAIDIGQVEGGFMQGYGLFTMEEMVYSPTGVVFSRGPGVYKIPSFTNIPRE 1274

Query: 1240 FRVSLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDS 1299
            F VSLL+   N +A+++SKA GEPPLFLA+S FF IK+AIRAAR       +   FRLDS
Sbjct: 1275 FNVSLLKASSNPRAVFSSKATGEPPLFLASSAFFGIKEAIRAARKDM---GIHGYFRLDS 1331

Query: 1300 PATPEKIRNACVDKFT 1315
            PAT  +IR ACVD+ T
Sbjct: 1332 PATAARIRMACVDQLT 1347
>ref|XP_001119950.1| PREDICTED: similar to rosy CG7642-PA [Apis mellifera]
          Length = 1356

 Score = 1444 bits (3739), Expect = 0.0,   Method: Composition-based stats.
 Identities = 710/1333 (53%), Positives = 942/1333 (70%), Gaps = 42/1333 (3%)

Query: 6    LVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNKI 65
            LVF+VNG++V++ N +PE TLL YLR KL L+GTKLGC EGGCGACTVM+SK DR    I
Sbjct: 29   LVFYVNGKEVIDNNVNPEWTLLWYLRNKLRLTGTKLGCAEGGCGACTVMISKLDRTTGII 88

Query: 66   VHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMY 125
             H + NACL  IC++H +AVTT+EGIGS KT LHPVQERIAK+HGSQCGFCTPGI+MSMY
Sbjct: 89   THLAVNACLTLICAMHGLAVTTIEGIGSVKTTLHPVQERIAKAHGSQCGFCTPGIIMSMY 148

Query: 126  TLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARD-----------------GG 168
             LLR  P+P+M+++E AFQGNLCRCTGYRPI++ ++TF  +                 G 
Sbjct: 149  ALLRTIPKPSMKDLEIAFQGNLCRCTGYRPIIEAYKTFTEEWEIMQLISKDKEKSLTNGE 208

Query: 169  CCGGDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLR 228
            C  G+    NCC    K   +     +F  +EF   DP+QE IFPP+L        + L 
Sbjct: 209  CSMGE----NCC----KKIPIVEPTEVFDSKEFCSYDPSQEIIFPPKLHISSYLDEEYLI 260

Query: 229  FEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELN 288
             +G+ VTW +  TL ELL LK Q+P+AK+VVGNTEIG+E+KFK + +P+++ P  I E++
Sbjct: 261  IKGKNVTWYRPKTLTELLYLKNQYPNAKIVVGNTEIGVEVKFKYLSYPVLIQPTLIKEMH 320

Query: 289  SVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASV 348
            ++E     ++ GA+  L  +EK+L + +A  P  +T +F  ++  L +FAGKQ+++VA+V
Sbjct: 321  TIEEYSKVLNIGASVTLVEMEKSLKNQIAIKPEYQTRIFNEIVNMLYYFAGKQIRNVAAV 380

Query: 349  GGNIITASPISDLNPVFMASGAKLTLVS-RGTRRTVQMDHTFFPGYRKTLLSPEEILLSI 407
            GGNI+T SPISDLNP+FMA+G KL + S +   R + MDHTFF GYR+ ++S EEILLSI
Sbjct: 381  GGNIMTGSPISDLNPIFMAAGVKLNVSSLKNGNRLIPMDHTFFKGYRQNVISSEEILLSI 440

Query: 408  EIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISAL 467
            +IP+S + +YF AFKQA RR+DDIA V   + V F+P +  V +  L +GGMA  T+ A 
Sbjct: 441  QIPFSEKNQYFIAFKQARRRDDDIAIVNMALNVFFEPESNIVNKAYLAFGGMAPTTVLAR 500

Query: 468  KTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKL 527
            KT    + + W ++LL+ +   L  EL L  + PGGMV +R +LTLS FFK +L + +K 
Sbjct: 501  KTCNIMIGRKWDKDLLETIYDSLLNELPLSDNVPGGMVKYRRSLTLSLFFKGFLHIAKKF 560

Query: 528  GQENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQA 587
                       L     SAT  F        Q +Q V K Q   D+VGR + H +A  QA
Sbjct: 561  QI--------FLPKEVESATEGFHTKKLKSSQYYQVVQKDQEANDLVGRSIVHASAYKQA 612

Query: 588  SGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSN-- 645
            +GEA+YCDD+P++ +EL L +V STRAHAKI  ID ++A  + G + F SA D+P     
Sbjct: 613  TGEAIYCDDMPKFVDELYLAVVLSTRAHAKILKIDATKALSMEGVIVFYSAKDIPEKQRW 672

Query: 646  ITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIEDAIK 704
               I  DE +F  +KVT  G +IGA+VA      Q+AA+ V+I YE L P II+IEDAIK
Sbjct: 673  FGPIFKDEEIFVSEKVTSHGQVIGAIVAINQTIAQKAARMVEIEYENLEPIIISIEDAIK 732

Query: 705  NNSFYGPELK-IEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMEL 763
            + SF+    K I  GD++K F E+ +++ GE+  G QEHFYLET+ T+A+PK E  E+E+
Sbjct: 733  HRSFFNQTPKHINNGDIEKAFIESQHILKGEVRTGAQEHFYLETNATLAIPK-EEDELEI 791

Query: 764  FVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRP 823
            F STQ+  + Q F++ +L + AN+IVVR KR+GGGFGGKE+RS V++  V  AAYK  +P
Sbjct: 792  FCSTQHPTELQKFISHLLNIHANKIVVRTKRLGGGFGGKESRSAVLALPVVFAAYKLRKP 851

Query: 824  VRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERAL 883
            VRCMLDRDED++++G RHPFL +YKVGF  +G +   +V  ++N G + DLS +++ERA+
Sbjct: 852  VRCMLDRDEDIIMSGARHPFLLKYKVGFDNSGLIKGAQVYIYNNAGYSYDLSPAVLERAM 911

Query: 884  FHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVR 943
            FH +N YKIP     G +CKTN+PS+TAFRGFGGPQGM +AE  +  +A        E+ 
Sbjct: 912  FHFENSYKIPVSDVYGFICKTNIPSSTAFRGFGGPQGMFLAETMIRHIAEYLNRDPVEIA 971

Query: 944  RKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIP 1003
              NLYKE D TH+NQKL   T+ RCW+EC+ SS Y+ R  +V K+N+EN +KK+GL I+P
Sbjct: 972  ELNLYKEEDTTHYNQKLFNCTIQRCWKECILSSNYNERLLQVQKYNRENRYKKKGLAIVP 1031

Query: 1004 TKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIY 1063
            TKFGISF++ FLNQAGAL+HVYTDGSVL++HGG EMGQGLHTKM+QVASR+LKI   KI+
Sbjct: 1032 TKFGISFSIAFLNQAGALVHVYTDGSVLISHGGVEMGQGLHTKMIQVASRSLKIKPDKIH 1091

Query: 1064 ISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYM 1123
            I+ET+T+ VPNTS TAAS S+DLNG A+  AC  I++RL+P   KNP+G+WE+WVT AY+
Sbjct: 1092 ITETATDKVPNTSATAASASSDLNGMAIMNACNKIMERLKPVIDKNPNGTWEEWVTTAYL 1151

Query: 1124 DTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDV 1183
            + +SLSA GFY+TP++ YSFETN+GN F+YF+YGVACSEVEIDCLTGDH+ L+TDIVMD+
Sbjct: 1152 ERISLSAAGFYKTPDIQYSFETNTGNVFNYFTYGVACSEVEIDCLTGDHQVLQTDIVMDL 1211

Query: 1184 GSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVS 1243
            G SLNPAIDIGQ+EGAF+QG GLFTLEE+ Y   G++ TRGP  YKIP F  IP  F VS
Sbjct: 1212 GESLNPAIDIGQIEGAFMQGYGLFTLEEMIYLRNGAIATRGPGAYKIPGFADIPEIFNVS 1271

Query: 1244 LLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATP 1303
            LL+   N +A+Y+SKAVGEPPLFLA+SIFFAIK+AI++AR  +   N+K  F+LD+PAT 
Sbjct: 1272 LLKGASNPRAVYSSKAVGEPPLFLASSIFFAIKEAIKSARTDY---NLKNYFQLDAPATA 1328

Query: 1304 EKIRNACVDKFTT 1316
             +IR AC+D FT+
Sbjct: 1329 ARIRLACIDDFTS 1341
>ref|XP_968229.1| PREDICTED: similar to CG7642-PA [Tribolium castaneum]
          Length = 1363

 Score = 1442 bits (3734), Expect = 0.0,   Method: Composition-based stats.
 Identities = 728/1363 (53%), Positives = 947/1363 (69%), Gaps = 36/1363 (2%)

Query: 2    TADKLVFFVNGRKVVEKNADPETTLLAYLRRKLG---------LSGTKLGCGEGGCGACT 52
            + + LVFFVNG+K+++   DPE TLL YLR  +          L GTKLGCGEGGCGACT
Sbjct: 6    SVNVLVFFVNGKKIIDNQVDPEWTLLYYLRISVSFDDDKWGVRLCGTKLGCGEGGCGACT 65

Query: 53   VMLSKYDRLQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQ 112
            VM+SKYDR+  K++H   NACLAP+CS+H  AVTTVEGIGST+TRLHPVQERIAK+HGSQ
Sbjct: 66   VMVSKYDRINKKVIHLPVNACLAPVCSVHGQAVTTVEGIGSTRTRLHPVQERIAKAHGSQ 125

Query: 113  CGFCTPGIVMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGG 172
            CGFCTPGIVMSMYTLLRN P+PTM ++E AFQGNLCRCTGYRPI++G++TF  +      
Sbjct: 126  CGFCTPGIVMSMYTLLRNSPKPTMNDMEIAFQGNLCRCTGYRPIIEGYKTFTEEWELMQA 185

Query: 173  DG----------------NNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPEL 216
            +                 +NP    ++  D        LFK  EFTP D TQEPIFPPEL
Sbjct: 186  NSKLNEGTGCGGGNGCCQDNPTRQESEDTDEKDPDEEVLFKTSEFTPYDCTQEPIFPPEL 245

Query: 217  LRLKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFP 276
                +  R+ L  +G+ VTW + + L +LL L+ QHP+AK+VVGNTE+G+E+KFK+M++P
Sbjct: 246  KLSDEYDRQYLVIKGKAVTWYRPTKLCDLLQLRKQHPNAKIVVGNTEVGVEVKFKHMVYP 305

Query: 277  MIVCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRW 336
            +IV P  IPEL+ +E+  +G+  GA+  L  V+  L+D + +LP +KT VFR + + L W
Sbjct: 306  VIVQPVLIPELSRIENTEEGVRVGASVTLMDVQGYLLDEMKRLPEEKTRVFRTITKMLNW 365

Query: 337  FAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVSR-GTRRTVQMDHTFFPGYRK 395
            FAGKQ++SV ++G NI+T SPISD+ P+ MA+   L L S  G  R V++D  FF GYRK
Sbjct: 366  FAGKQIRSVGALGSNIMTGSPISDMLPILMANEVVLELQSADGGVRKVRLDSHFFTGYRK 425

Query: 396  TLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALC 455
            T++ P+EILL+I IPY+    Y  A+KQA RREDDIA V + + V F+P T  + ++ + 
Sbjct: 426  TIVLPDEILLAIHIPYTHRDRYCYAYKQARRREDDIAIVNAAVNVTFEPQTDIISDINIA 485

Query: 456  YGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSF 515
            +GG++ +T++ALKT        W  + L+     L E+L L P APGGM+ +R +LTLS 
Sbjct: 486  FGGVSFKTVTALKTRTNLKGLPWNRQTLERAFDYLQEDLPLDPGAPGGMIQYRRSLTLSL 545

Query: 516  FFKFYLTVLQKLGQENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVG 575
            FFK +L +  +L +        + D    S    F +      Q F  VP  Q + D + 
Sbjct: 546  FFKAFLAISLELQKYVPHVTVDQRD---LSGIEGFHEKEYKSSQYFTVVPHTQQKTDALQ 602

Query: 576  RPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCF 635
            RP+ H++A  QA+GEA+Y DDIP +ENEL L  VTST+AHAKI SID SEA ++ G   F
Sbjct: 603  RPIVHMSAYKQATGEAIYLDDIPYFENELYLAFVTSTKAHAKILSIDPSEALEMEGVHYF 662

Query: 636  ISADDVPGSNIT--GICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL 693
            +SA D+   + T   I +DE VF  +KVT  G IIG VVA      Q AA+ VK+ YE++
Sbjct: 663  VSAKDIDKKHNTMGSIVHDERVFYNEKVTSQGQIIGGVVAVDQSTAQSAARKVKVVYEDI 722

Query: 694  -PAIITIEDAIKNNSFYGPELK--IEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCT 750
             P I+TI DAIK NS++G      I KGD++K   EA +V+  E  +GGQEHFYLET C 
Sbjct: 723  EPVIVTIPDAIKYNSYHGNGRHKLIVKGDIEKVLREAPHVLESECQMGGQEHFYLETQCV 782

Query: 751  IAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVS 810
            +AVPK E  EME++ STQN  +  + +A++LG+  N+I  +VKR+GGGFGGKE+++ +V+
Sbjct: 783  LAVPKKEDCEMEIYSSTQNPTEVAAMLAEVLGIQQNKIAAKVKRLGGGFGGKESKAMMVA 842

Query: 811  TAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGN 870
              VA+AA K  RP+RCMLDRDED+++TGGRHPFL +YKV F   G ++  ++  ++N G 
Sbjct: 843  IPVAIAAVKLNRPIRCMLDRDEDIVMTGGRHPFLMKYKVAFDDNGKILGADIKLYNNCGY 902

Query: 871  TQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSE 930
            + DLS S++ERA+ H +N YKIP +R  G +CKTNLPSNTAFRGFGGPQGM  AEC + +
Sbjct: 903  STDLSPSVLERAMTHFENSYKIPVVRVEGFMCKTNLPSNTAFRGFGGPQGMYAAECILQD 962

Query: 931  VAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNK 990
            VA         +   NLYKEGD TH+NQKL   TL +CW EC+ SS YH ++ EV++FN+
Sbjct: 963  VADYLQKDPVTLSELNLYKEGDFTHYNQKLVNCTLDKCWHECIQSSNYHEKRKEVERFNR 1022

Query: 991  ENCWKKRGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQV 1050
            EN +KKRGL +IPTK+GI+FT P LNQAG LL VY DGSVLL+HGG EMGQGL+TKM+QV
Sbjct: 1023 ENRYKKRGLSVIPTKYGIAFTAPHLNQAGCLLIVYADGSVLLSHGGIEMGQGLYTKMIQV 1082

Query: 1051 ASRALKIPTSKIYISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNP 1110
            ASR L+IP  KI+  ET+T+ VPNTSPTAAS  +DLNG AV  AC+ I +RL P+K+ NP
Sbjct: 1083 ASRMLEIPVDKIHTVETATDKVPNTSPTAASSGSDLNGMAVMEACKVIKERLRPFKEANP 1142

Query: 1111 SGSWEDWVTAAYMDTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTG 1170
             G+WE WV  AY   VSLSATGFY+TP++GY++ET  GN F+YF+YGVAC EVEID LTG
Sbjct: 1143 KGTWEQWVRKAYFSRVSLSATGFYKTPDIGYNWETGEGNMFNYFTYGVACCEVEIDTLTG 1202

Query: 1171 DHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKI 1230
            DH+  R DIVMD+G SLNPAIDIGQ+EGAF+QG GLF LEEL YSP G+ +TRGP TYK+
Sbjct: 1203 DHEVRRIDIVMDLGESLNPAIDIGQIEGAFMQGYGLFVLEELVYSPTGTNYTRGPGTYKL 1262

Query: 1231 PAFGSIPIEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNN 1290
            P FG IP EF VSLL+   N +A+++SKAVGEPPLFL +S+ +AIKDAI+AAR ++    
Sbjct: 1263 PGFGDIPGEFNVSLLKGVSNPRAVFSSKAVGEPPLFLGSSVLYAIKDAIKAARRENGYEP 1322

Query: 1291 VKELFRLDSPATPEKIRNACVDKFTTLCVTGVPENCKPWSVRV 1333
             K  FRLDSPAT  +IR AC D  T+      P + KPW+V V
Sbjct: 1323 TK--FRLDSPATAARIRMACQDNITSKFKDPEPGSFKPWNVYV 1363
>ref|NP_001037325.1| xanthine dehydrogenase [Bombyx mori]
 dbj|BAA07348.1| xanthine dehydrogenase [Bombyx mori]
          Length = 1356

 Score = 1437 bits (3721), Expect = 0.0,   Method: Composition-based stats.
 Identities = 711/1349 (52%), Positives = 937/1349 (69%), Gaps = 32/1349 (2%)

Query: 5    KLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNK 64
            +LVF+VNG+KV+E + DPE TLL YLR+KL L+GTKLGC EGGCGACTVM+SKY+R +NK
Sbjct: 16   ELVFYVNGKKVIESSPDPEWTLLWYLRKKLRLTGTKLGCAEGGCGACTVMVSKYNRQENK 75

Query: 65   IVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSM 124
            I+H + NACLAP+C++H +AVTTVEGIGSTKT+LHPVQERIAK+HGSQCGFCTPGIVMSM
Sbjct: 76   IIHLAVNACLAPVCAMHGLAVTTVEGIGSTKTKLHPVQERIAKAHGSQCGFCTPGIVMSM 135

Query: 125  YTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARD-------------GGCCG 171
            YTLLR+       ++E AFQGNLCRCTGYR I++G++TF  D             G C  
Sbjct: 136  YTLLRSCKNIQYSDLEVAFQGNLCRCTGYRAIIEGYKTFIEDWEAQRIVKNGPQNGTCAM 195

Query: 172  GDGNNPNCCMNQKK--DHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRF 229
            G     +CC N+    + + S S  +F    F P D +QEPIFPPEL        + + +
Sbjct: 196  GK----DCCKNKSDSCEEADSESQYIFDKSSFLPYDSSQEPIFPPELKLSSIYDSQYVIY 251

Query: 230  EGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNS 289
             G++ TW + + ++ +L LK + P+AK+VVGN+E+G+E+KFK  ++P+I+ P  +PELN+
Sbjct: 252  RGKQTTWYRPTNIETVLSLKDKFPNAKVVVGNSEVGVEVKFKRCVYPIIIMPNCVPELNN 311

Query: 290  VEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVG 349
            +     G++ GA+  L+ +E+T  + + KLP  KT V   ++E L WFAGKQ+++VA++G
Sbjct: 312  ITENEHGLTVGASVTLNDIEETFREYIKKLPPYKTRVLTTIVEMLNWFAGKQIRNVAAIG 371

Query: 350  GNIITASPISDLNPVFMASGAKLTLVSR-GTRRTVQMDHTFFPGYRKTLLSPEEILLSIE 408
            GN++T SPISDLNP+ M+   KL L+S+    RTV MD TFF GYRK ++   EILLSIE
Sbjct: 372  GNVMTGSPISDLNPILMSLKVKLNLLSQENGHRTVLMDETFFTGYRKNVVKSNEILLSIE 431

Query: 409  IPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALK 468
            IP+S + +Y  A KQA RREDDI+ VTS + V F+  T  ++ + L +GGMA  T  A  
Sbjct: 432  IPFSTKFQYLKAIKQAKRREDDISIVTSAVNVEFEENTNVIKYINLAFGGMAPVTKIATN 491

Query: 469  TTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLG 528
            T        W E +L+   + L +EL L P APGG + FR  LT+S F K YL + + + 
Sbjct: 492  TGNVLKGLKWNENMLEKAYSLLIDELPLDPSAPGGNIQFRRALTMSLFLKSYLAIGKAMS 551

Query: 529  QENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQAS 588
             + +      ++  + S    F  + P   Q F+ V + Q + D VGRP+ H++A  QA+
Sbjct: 552  SDYVYGDL--IESYYGSGADSFHGNVPKSSQYFELVGEKQLKSDAVGRPIQHMSAYKQAT 609

Query: 589  GEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPG--SNI 646
            GEA+YCDD+P  E EL L  V S++AHAK+ S+D  +A   PG + F SA D+    ++I
Sbjct: 610  GEAIYCDDMPIAEGELYLAFVLSSKAHAKLISVDAKKALAEPGVIAFYSAKDLTKEQNSI 669

Query: 647  TGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIEDAIKN 705
              I +DE +FA+DKV   G  IG +VA      Q AA+ VK+ YEE+ P I+TIEDAIK 
Sbjct: 670  GPIFHDEELFARDKVLSQGQTIGVIVAVDQATAQAAARMVKVEYEEIQPIIVTIEDAIKY 729

Query: 706  NSFYGPEL--KIEKGDLKKGFSEADNVV-SGEIYIGGQEHFYLETHCTIAVPKGEAGEME 762
            NSFY P+    I++G++K  F + +N++  G   +GGQEHFYLETH   A+PK E  E++
Sbjct: 730  NSFY-PQFPKTIKRGNVKAVFDDKNNIIIEGRCRMGGQEHFYLETHAAFAIPKKEDDELQ 788

Query: 763  LFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGR 822
            +F S+Q+  +    V+ +L VP NRIV RVKRMGGGFGGKE+R  +V+  VALAA+K  R
Sbjct: 789  IFCSSQHPSEIAKLVSHILHVPMNRIVARVKRMGGGFGGKESRGMLVALPVALAAHKLNR 848

Query: 823  PVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERA 882
            PV CMLDRDEDM +TG RHPFL +YK    K G +V   V+ ++N G + DLS  ++ERA
Sbjct: 849  PVWCMLDRDEDMQMTGTRHPFLIKYKAAATKEGKIVGAVVNIYNNGGYSTDLSGPVVERA 908

Query: 883  LFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEV 942
            +FH +N Y IPN   TG +C+TNLPSNTAFRGFGGPQGM  A   + E+A   G   EE+
Sbjct: 909  MFHFENAYYIPNCEVTGYVCRTNLPSNTAFRGFGGPQGMFGAGNMVREIAHRLGKSPEEI 968

Query: 943  RRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCII 1002
             R NLY+  + TH+ Q L   TL RCW+EC+ +S    RK ++ +FNK++ W+KRG+ II
Sbjct: 969  SRLNLYRGNNTTHYGQVLTYCTLQRCWDECVQNSNLAERKLKIKEFNKQHRWRKRGISII 1028

Query: 1003 PTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI 1062
            PTKFGI+FT   LNQAGAL+ VY DGSVLL+HGGTEMGQGLHTKM+QVA+RAL I  SKI
Sbjct: 1029 PTKFGIAFTEKLLNQAGALVLVYVDGSVLLSHGGTEMGQGLHTKMIQVATRALGIDVSKI 1088

Query: 1063 YISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAY 1122
            +ISETST+ VPNTS TAAS  +DLNG AV  AC+ I+KRL+PY  KNP G WE+WV+AAY
Sbjct: 1089 HISETSTDKVPNTSATAASAGSDLNGMAVLEACEKIMKRLKPYIDKNPDGKWENWVSAAY 1148

Query: 1123 MDTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMD 1182
            +D VSLSATGF+ TP++G+ F+T SG PF+YF+YGVAC+EVEIDCL+GDH+ LRTDIVMD
Sbjct: 1149 VDRVSLSATGFHATPDIGFDFKTTSGKPFNYFTYGVACTEVEIDCLSGDHQVLRTDIVMD 1208

Query: 1183 VGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRV 1242
            +G SLNPAIDIGQ+EG F+QG GLFT+EEL YSP G+L++RGP  YKIP FG    EF V
Sbjct: 1209 LGESLNPAIDIGQIEGGFIQGYGLFTIEELIYSPTGTLYSRGPGAYKIPGFGGYSSEFNV 1268

Query: 1243 SLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPAT 1302
            SLL+  PN +A+Y+SKAVGEPPLFLA+S +FAI +AI+AARA      V   F +++PAT
Sbjct: 1269 SLLKGAPNPRAVYSSKAVGEPPLFLASSAYFAIHEAIKAARAD---AGVPLEFDMEAPAT 1325

Query: 1303 PEKIRNACVDKFTTLCVTGVPENCKPWSV 1331
              +IR AC D  T       P +  PW+V
Sbjct: 1326 SARIRMACEDHITKKLDKPDPNSFVPWNV 1354
>gb|EDL38419.1| xanthine dehydrogenase, isoform CRA_c [Mus musculus]
          Length = 748

 Score = 1422 bits (3682), Expect = 0.0,   Method: Composition-based stats.
 Identities = 671/739 (90%), Positives = 710/739 (96%), Gaps = 5/739 (0%)

Query: 536  CGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCD 595
            CGKLDPTFASATLLFQKDPPA+VQLFQEVPKGQSEEDMVGRP+PHLAADMQASGEAVYCD
Sbjct: 14   CGKLDPTFASATLLFQKDPPANVQLFQEVPKGQSEEDMVGRPMPHLAADMQASGEAVYCD 73

Query: 596  DIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETV 655
            DIPRYENELSLRLVTSTRAHAKI SIDTSEAKKVPGFVCF++++DVPGSNITGI NDETV
Sbjct: 74   DIPRYENELSLRLVTSTRAHAKIMSIDTSEAKKVPGFVCFLTSEDVPGSNITGIFNDETV 133

Query: 656  FAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKI 715
            FAKD+VTCVGHIIGAVVADTPEH  RAA+GVKITYE+LPAIITI+DAIKNNSFYGPE+KI
Sbjct: 134  FAKDEVTCVGHIIGAVVADTPEHAHRAARGVKITYEDLPAIITIQDAIKNNSFYGPEVKI 193

Query: 716  EKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQS 775
            EKGDLKKGFSEADNVVSGE+YIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQS
Sbjct: 194  EKGDLKKGFSEADNVVSGELYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQS 253

Query: 776  FVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDML 835
            F+AKMLGVP NRIVVRVKRMGGGFGGKETRST++STAVALAAYKTGRPVRCMLDRDEDML
Sbjct: 254  FIAKMLGVPDNRIVVRVKRMGGGFGGKETRSTLISTAVALAAYKTGRPVRCMLDRDEDML 313

Query: 836  ITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNI 895
            ITGGRHPFLA+YKVGFMKTGT+VALEV HFSN GN++DLS+SIMERA+FHMDN YKIPNI
Sbjct: 314  ITGGRHPFLAKYKVGFMKTGTIVALEVAHFSNGGNSEDLSRSIMERAVFHMDNAYKIPNI 373

Query: 896  RGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTH 955
            RGTGR+CKTNLPSNTAFRGFGGPQGMLIAE WMSEVAVTCG+PAEEVRRKN+YKEGDLTH
Sbjct: 374  RGTGRICKTNLPSNTAFRGFGGPQGMLIAEYWMSEVAVTCGLPAEEVRRKNMYKEGDLTH 433

Query: 956  FNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFL 1015
            FNQKLEGFTLPRCW+EC+ASSQY ARK EV+KFN+ENCWKKRGLCIIPTKFGISFT+ FL
Sbjct: 434  FNQKLEGFTLPRCWDECIASSQYQARKMEVEKFNRENCWKKRGLCIIPTKFGISFTLSFL 493

Query: 1016 NQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNT 1075
            NQ GAL+HVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKI+I+ETSTNTVPNT
Sbjct: 494  NQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHITETSTNTVPNT 553

Query: 1076 SPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYR 1135
            SPTAAS SADLNGQA+Y ACQTILKRLEP+KKKNPSGSWE WV  AY   VSLSATGFY+
Sbjct: 554  SPTAASASADLNGQAIYEACQTILKRLEPFKKKNPSGSWESWVMDAYTSAVSLSATGFYK 613

Query: 1136 TPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQ 1195
            TPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQ
Sbjct: 614  TPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQ 673

Query: 1196 VEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIY 1255
            VEGAFVQGLGLFT+EELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNK+AIY
Sbjct: 674  VEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKRAIY 733

Query: 1256 ASKAVGEPPLFLAASIFFA 1274
            ASK   +P   +AAS F A
Sbjct: 734  ASKK--DP---VAASFFLA 747
>sp|P08793|XDH_CALVI Xanthine dehydrogenase (XD)
          Length = 1353

 Score = 1416 bits (3665), Expect = 0.0,   Method: Composition-based stats.
 Identities = 700/1343 (52%), Positives = 939/1343 (69%), Gaps = 19/1343 (1%)

Query: 2    TADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRL 61
            T   L+FFVNG+KV++ N DPE TLL YLR KL L GTKLGCGEGGCGACTVM+S+ D L
Sbjct: 15   TFSTLIFFVNGKKVIDTNPDPECTLLTYLREKLRLCGTKLGCGEGGCGACTVMISRIDTL 74

Query: 62   QNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIV 121
             N+I H + NACL P+C++H  AVTTVEGIGST+TRLHPVQER+AK+HGSQCGFCTPGIV
Sbjct: 75   TNRIKHIAVNACLTPVCAMHGSAVTTVEGIGSTRTRLHPVQERLAKAHGSQCGFCTPGIV 134

Query: 122  MSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGN---NPN 178
            MSMY LLRN  +P+M+++E AFQGNLCRCTGYRPIL+G++TF ++ GC  GD     N N
Sbjct: 135  MSMYALLRNLSQPSMKDLEIAFQGNLCRCTGYRPILEGYKTFTKEFGCAMGDKCCKVNGN 194

Query: 179  CCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQ 238
             C    ++    +   LF+  EF P DP+QEPIFPPEL   KD   + L ++GER TW +
Sbjct: 195  KCGEGMENGGDMVDDKLFEKSEFVPFDPSQEPIFPPELQLNKDWDSQTLVYKGERATWYR 254

Query: 239  ASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGIS 298
               L++LL +KAQ P+AKLVVGNTEIG+E+KFK+ L+P++V P  + E+  V+   D I 
Sbjct: 255  PGNLEDLLKIKAQFPEAKLVVGNTEIGVEVKFKHFLYPVLVNPTKVKEMIDVQELEDSIY 314

Query: 299  FGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPI 358
            FGA+  L  +++ L  ++ KLP  +T  F+  +  L +FAGKQ+++VAS+GGNI+T SPI
Sbjct: 315  FGASVSLMDIDRILRSSIEKLPEHQTRFFQCAVNMLHYFAGKQIRNVASLGGNIMTGSPI 374

Query: 359  SDLNPVFMASGAKLTLVS----RGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSRE 414
            SD+NPV MA   K  +      +   R V M   FF GYRK ++ P EIL+ +  P + E
Sbjct: 375  SDMNPVLMAGAVKFKVAKYVEGQIKYREVCMASGFFTGYRKNVIEPTEILVGLYFPKTLE 434

Query: 415  GEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQL 474
             +Y  AFKQA RR+DDIA V + + V   P +  V ++ + +GGMA  T+ A +T    +
Sbjct: 435  HQYVVAFKQAKRRDDDIAIVNAAINVFIDPRSITVDKVYMAFGGMAPTTVLATRTADIMV 494

Query: 475  SKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLED 534
             + W + L++ V   L  EL L P APGGM+ +R +L +S FFK YLT+ Q+L +  +  
Sbjct: 495  KQQWNKVLMERVVENLCAELPLAPSAPGGMIAYRRSLVVSLFFKAYLTITQQLIKSGILP 554

Query: 535  KCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYC 594
            +   L     S + +F        QLF++V   QSE D +GRP  H +A  QA+GEA+YC
Sbjct: 555  Q-DSLPQEELSGSDVFHTPALKSAQLFEKVSNKQSECDPIGRPKIHASALKQATGEAIYC 613

Query: 595  DDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPG--SNITGICND 652
            DD+PR ENEL L LV ST+AHAKI SID SEA  +PG   F S+ D+    + +  + +D
Sbjct: 614  DDMPRMENELYLALVLSTKAHAKILSIDASEALAMPGVHAFFSSKDITQHENEVGPVFHD 673

Query: 653  ETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIEDAIKNNSFYGP 711
            E VFA D V C G +IGA+ AD P  + + A+ V I YE++ P IITIE AI++ S++ P
Sbjct: 674  EEVFASDMVYCQGQVIGAIAADNPNFSSKTARKVTIEYEDIKPVIITIEQAIEHKSYF-P 732

Query: 712  ELK--IEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQN 769
            +     E GD++K FSEAD+V  G   +GGQEHFYLETH ++AVP+ ++ E+E+F STQ+
Sbjct: 733  DYPRFTEIGDVEKAFSEADHVYEGSCRMGGQEHFYLETHASLAVPR-DSDEIEIFCSTQH 791

Query: 770  TMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLD 829
              + Q  VA +L   A+R+V R KR+GGGFGGKE+R+  V+  VALA ++  RP+RCMLD
Sbjct: 792  PSEVQKLVAHVLSTSAHRVVCRAKRLGGGFGGKESRAIAVALPVALACHRLRRPIRCMLD 851

Query: 830  RDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNC 889
            RDEDM+ITG RHPFL +YK+ F   G +    ++ ++N G + DLS S++ERA+FH +NC
Sbjct: 852  RDEDMMITGTRHPFLFKYKIAFTSEGRLTGCYIECYNNAGWSMDLSFSVLERAMFHFENC 911

Query: 890  YKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYK 949
            YKIPNI+  G +CKTNLPSNTAFRGFGGPQGM   E  + +VA   G    E+ ++N YK
Sbjct: 912  YKIPNIKVGGWVCKTNLPSNTAFRGFGGPQGMFAGEHIIRDVARILGKDYLEIMKQNFYK 971

Query: 950  EGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGIS 1009
            EGD+TH+ QKL+ F + +C+ +CL  S Y+ ++ E+++FN+ + W+KRG+ ++PTK+GI+
Sbjct: 972  EGDITHYQQKLDNFPIEKCFYDCLQQSNYYQKRKEIEEFNRNHRWRKRGISLVPTKYGIA 1031

Query: 1010 FTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETST 1069
            F V  LNQAGAL+++Y DGSVLL+HGG E+GQGLHTKM+Q  +RAL+IP   I+ISET+T
Sbjct: 1032 FGVSHLNQAGALINIYADGSVLLSHGGVEIGQGLHTKMIQCCARALQIPIEFIHISETAT 1091

Query: 1070 NTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLS 1129
            + VPNTSPTAAS  +DLNG AV  AC+ + KRL P K+ NP+GSW +W+  AY + VSLS
Sbjct: 1092 DKVPNTSPTAASSGSDLNGMAVLDACEKLNKRLAPIKEANPNGSWTEWINKAYFERVSLS 1151

Query: 1130 ATGFYRTPNLGYS-FETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLN 1188
            ATGFYR P++GY   +  +   ++YF+ GV  S VEIDCLTGDH+ L TDIVMD+GSSLN
Sbjct: 1152 ATGFYRMPDIGYDPVQNPNALMYNYFTNGVGSSIVEIDCLTGDHQVLSTDIVMDIGSSLN 1211

Query: 1189 PAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDC 1248
            PAIDIGQ+EGAF+QG GLFTLEE+ YSP+G L++RGP  YK+P F  IP EF V++L   
Sbjct: 1212 PAIDIGQIEGAFMQGYGLFTLEEMIYSPQGVLYSRGPGMYKLPGFADIPGEFNVTILTGA 1271

Query: 1249 PNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRN 1308
             N +A+Y+SKAVGEPPLF+  S+FFAIK+AI +AR     N + E F+L+SPAT  +IR 
Sbjct: 1272 ANPRAVYSSKAVGEPPLFIGCSVFFAIKEAITSARLM---NGLSEDFKLESPATSARIRM 1328

Query: 1309 ACVDKFTTLCVTGVPENCKPWSV 1331
            AC D+FT L       +  PW++
Sbjct: 1329 ACQDEFTNLIEQPPAGSYVPWNI 1351
>ref|XP_001358503.1| GA20500-PA [Drosophila pseudoobscura]
 gb|EAL27642.1| GA20500-PA [Drosophila pseudoobscura]
          Length = 1336

 Score = 1412 bits (3656), Expect = 0.0,   Method: Composition-based stats.
 Identities = 705/1345 (52%), Positives = 931/1345 (69%), Gaps = 30/1345 (2%)

Query: 5    KLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNK 64
            +LVFFVNG+KV + N DPE TLL YLR KL L GTKLGC EGGCGACTV++S+ DR QNK
Sbjct: 2    ELVFFVNGKKVTDTNPDPECTLLTYLRDKLRLCGTKLGCAEGGCGACTVVISRMDRGQNK 61

Query: 65   IVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSM 124
            I H + NACL P+C++H  AVTTVEGIGST+TRLHPVQER+AK+HGSQCGFCTPGIVMSM
Sbjct: 62   IRHLAVNACLTPVCAMHGCAVTTVEGIGSTRTRLHPVQERLAKAHGSQCGFCTPGIVMSM 121

Query: 125  YTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMNQK 184
            Y LLR+  +P+M ++E AFQGNLCRCTGYRPIL+G++TF ++  C  GD     CC    
Sbjct: 122  YALLRSAEQPSMRDLEVAFQGNLCRCTGYRPILEGYKTFTKEFACGMGD----KCCKVNG 177

Query: 185  K-----DHSVSLSP-SLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQ 238
            K     D + S++  +LF+  +F PLDP+QEPIFPPEL        + L F  ERVTW +
Sbjct: 178  KGCGGGDDTQSVTDDTLFERSQFQPLDPSQEPIFPPELQLTPTYDSESLIFSSERVTWYR 237

Query: 239  ASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGIS 298
             +TL+ELL LK+ HP AKLVVGNTE+G+E+KFK+ L+P ++ P  +PEL  V    + I 
Sbjct: 238  PTTLQELLQLKSDHPSAKLVVGNTEVGVEVKFKHFLYPHLINPTQVPELLEVRESEESIY 297

Query: 299  FGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPI 358
            FGAA  L  ++  L   + +LP  +T +F+  ++ L +FAGKQ+++VA +GGNI+T SPI
Sbjct: 298  FGAAVSLMEIDALLRQRIEELPEAQTRLFQCAVDMLHYFAGKQIRNVACLGGNIMTGSPI 357

Query: 359  SDLNPVFMASGAKLTLVS----RGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSRE 414
            SD+NPV  A+GA+L + S    + + RTV M   FF GYR+ ++ P E+LL I    +  
Sbjct: 358  SDMNPVLTAAGARLEVASLVGGKTSHRTVHMGTGFFTGYRRNVIEPHEVLLGIHFQKTTP 417

Query: 415  GEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQL 474
             ++  AFKQA RR+DDIA V + + V F+P T  V  +++ +GGMA  T+ A +T+Q  +
Sbjct: 418  DQHVVAFKQARRRDDDIAIVNAAVNVRFEPRTNVVAGISMAFGGMAPTTVLAPRTSQLMV 477

Query: 475  SKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLED 534
             +     L++ V   L  EL L   APGGM+ +R  L +S  FK YL++ +KL +  +  
Sbjct: 478  KQPLDHHLVERVAESLCGELPLAASAPGGMIAYRRALVVSLIFKAYLSISRKLSEAGIIS 537

Query: 535  KCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYC 594
                +     S   LF        QLF+ V   Q   D +GRP  H AA  QA+GEA+Y 
Sbjct: 538  T-DAIPAEERSGAELFHTPVLRSAQLFERVCSEQPVCDPIGRPEVHAAALKQATGEAIYT 596

Query: 595  DDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPG--SNITGICND 652
            DDIPR + EL L LV ST+  AKI  +D SEA  + G   F S  D+    + +  + +D
Sbjct: 597  DDIPRMDGELYLGLVLSTKPRAKITKLDASEALALEGVHAFFSHKDLTEHENEVGPVFHD 656

Query: 653  ETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEEL-PAIITIEDAIKNNSFYGP 711
            E VFA  +V C G I+GAV AD     QRAA+ V++ YEEL P I+TIE AI++ S++ P
Sbjct: 657  EHVFAAAEVHCYGQIVGAVAADNKALAQRAARLVRVEYEELAPVIVTIEQAIEHGSYF-P 715

Query: 712  ELK--IEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQN 769
            +    + KG++++ F+ A++   G   +GGQEHFYLETH  +AVP+ ++ E+ELF STQ+
Sbjct: 716  DYPRYVNKGNVEEAFAAAEHTYEGSCRMGGQEHFYLETHAAVAVPR-DSDELELFCSTQH 774

Query: 770  TMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLD 829
              + Q  VA +  +PA+R+V R KR+GGGFGGKE+R   V+  VALAAY+  RPVRCMLD
Sbjct: 775  PSEVQKLVAHVTTLPAHRVVCRAKRLGGGFGGKESRGISVALPVALAAYRLRRPVRCMLD 834

Query: 830  RDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNC 889
            RDEDMLITG RHPFL +YKV F   G + A +++ ++N G + DLS S++ERA++H +NC
Sbjct: 835  RDEDMLITGTRHPFLFKYKVAFASDGLITACDIECYNNAGWSMDLSFSVLERAMYHFENC 894

Query: 890  YKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYK 949
            Y+IPN+R  G +CKTNLPSNTAFRGFGGPQGM   E  + +VA   G    +V R N YK
Sbjct: 895  YRIPNVRVGGWVCKTNLPSNTAFRGFGGPQGMFAGEHIIRDVARIVGRDVLDVMRLNFYK 954

Query: 950  EGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGIS 1009
             GD+TH+NQKLE F + RC ++CLA S+YH +++E+ KFN+EN W+KRG+ +IPTK+GI+
Sbjct: 955  TGDITHYNQKLEHFPIERCLDDCLAQSRYHEKRTEIAKFNRENRWRKRGMAVIPTKYGIA 1014

Query: 1010 FTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETST 1069
            F V  LNQAGAL++VY DGSVLL+HGG E+GQGL+TKM+Q A+RAL IP   I+ISET+T
Sbjct: 1015 FGVMHLNQAGALINVYGDGSVLLSHGGVEIGQGLNTKMIQCAARALGIPIELIHISETAT 1074

Query: 1070 NTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLS 1129
            + VPNTSPTAASV +DLNG AV  AC+ + KRL P K+  P G+W++W+  AY D VSLS
Sbjct: 1075 DKVPNTSPTAASVGSDLNGMAVLDACEKLNKRLAPIKEALPQGTWQEWINKAYFDRVSLS 1134

Query: 1130 ATGFYRTPNLGYSFETN-SGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLN 1188
            ATGFY  P +GY  ETN +   + Y++ GV  S VEIDCLTGDH+ L TDIVMD+GSS+N
Sbjct: 1135 ATGFYAMPGIGYHPETNPNARTYSYYTNGVGISVVEIDCLTGDHQVLSTDIVMDIGSSIN 1194

Query: 1189 PAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDC 1248
            PAIDIGQ+EGAF+QG GLFTLEEL YSP+G L++RGP  YK+P F  IP EF VSLL   
Sbjct: 1195 PAIDIGQIEGAFMQGYGLFTLEELMYSPQGMLYSRGPGMYKLPGFADIPGEFNVSLLTGA 1254

Query: 1249 PNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQH--TGNNVKELFRLDSPATPEKI 1306
            PN +A+Y+SKAVGEPPLF+ +S FFAIK+AI AAR +   TG+     F L++P+T  +I
Sbjct: 1255 PNPRAVYSSKAVGEPPLFIGSSAFFAIKEAIAAARQEQGLTGD-----FPLEAPSTSARI 1309

Query: 1307 RNACVDKFTTLCVTGVPENCKPWSV 1331
            R AC DKFT L       +  PW++
Sbjct: 1310 RMACQDKFTNLLEIPEEGSFTPWNI 1334
Searching..................................................done Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

gb|AAA75287.1|  xanthine dehydrogenase                           2337   0.0  
ref|NP_000370.2|  xanthine dehydrogenase [Homo sapiens] >gi|...  2326   0.0  
ref|XP_525729.2|  PREDICTED: xanthine dehydrogenase [Pan tro...  2325   0.0  
pdb|2E1Q|A  Chain A, Crystal Structure Of Human Xanthine Oxi...  2324   0.0  
ref|XP_001501608.1|  PREDICTED: similar to xanthine dehydrog...  2297   0.0  
ref|NP_001009217.1|  xanthine dehydrogenase [Felis catus] >g...  2289   0.0  
ref|NP_001116410.1|  xanthine dehydrogenase/oxidase [Oryctol...  2283   0.0  
gb|ABL96618.1|  xanthine oxidoreductase [Capra hircus]           2281   0.0  
gb|AAI41184.1|  Xanthine dehydrogenase [Mus musculus]            2279   0.0  
gb|EDL38417.1|  xanthine dehydrogenase, isoform CRA_a [Mus m...  2278   0.0  
ref|NP_035853.2|  xanthine dehydrogenase [Mus musculus]          2278   0.0  
sp|Q00519|XDH_MOUSE  Xanthine dehydrogenase/oxidase [Include...  2277   0.0  
gb|EDM02851.1|  rCG61833 [Rattus norvegicus]                     2275   0.0  
dbj|BAE26022.1|  unnamed protein product [Mus musculus]          2275   0.0  
emb|CAA44705.1|  xanthine dehydrogenase [Mus musculus]           2274   0.0  
ref|XP_540143.2|  PREDICTED: similar to Xanthine dehydrogena...  2273   0.0  
ref|XP_862631.1|  PREDICTED: similar to Xanthine dehydrogena...  2273   0.0  
ref|XP_862539.1|  PREDICTED: similar to Xanthine dehydrogena...  2271   0.0  
ref|XP_862684.1|  PREDICTED: similar to Xanthine dehydrogena...  2270   0.0  
ref|NP_058850.1|  xanthine dehydrogenase [Rattus norvegicus]...  2270   0.0  
ref|XP_001501696.1|  PREDICTED: similar to xanthine dehydrog...  2268   0.0  
pdb|1WYG|A  Chain A, Crystal Structure Of A Rat Xanthine Deh...  2267   0.0  
sp|P80457|XDH_BOVIN  Xanthine dehydrogenase/oxidase [Include...  2265   0.0  
ref|NP_776397.1|  xanthine dehydrogenase [Bos taurus] >gi|11...  2264   0.0  
pdb|2E3T|A  Chain A, Crystal Structure Of Rat Xanthine Oxido...  2263   0.0  
gb|AAD17938.1|  xanthine:oxygen oxidoreductase [Tragelaphus ...  2261   0.0  
pdb|1N5X|A  Chain A, Xanthine Dehydrogenase From Bovine Milk...  2261   0.0  
ref|XP_862658.1|  PREDICTED: similar to Xanthine dehydrogena...  2258   0.0  
ref|XP_862565.1|  PREDICTED: similar to Xanthine dehydrogena...  2256   0.0  
ref|NP_990458.1|  xanthine dehydrogenase [Gallus gallus] >gi...  2246   0.0  
gb|AAD17937.1|  xanthine:oxygen oxidoreductase [Syncerus caf...  2245   0.0  
emb|CAA67117.1|  xanthine dehydrogenase [Bos taurus]             2239   0.0  
ref|XP_862593.1|  PREDICTED: similar to Xanthine dehydrogena...  2224   0.0  
ref|XP_862613.1|  PREDICTED: similar to Xanthine dehydrogena...  2216   0.0  
ref|NP_524337.1|  rosy CG7642-PA [Drosophila melanogaster] >...  2172   0.0  
emb|CAA68409.1|  xanthine dehydrogenase [Drosophila melanoga...  2164   0.0  
sp|P22811|XDH_DROPS  Xanthine dehydrogenase (XD) (Protein ro...  2150   0.0  
ref|XP_001358503.1|  GA20500-PA [Drosophila pseudoobscura] >...  2150   0.0  
gb|AAQ17526.1|  xanthine dehydrogenase [Drosophila simulans]     2146   0.0  
sp|P91711|XDH_DROSU  Xanthine dehydrogenase (XD) (Protein ro...  2143   0.0  
gb|AAA29022.1|  xanthine dehydrogenase (Xdh)                     2138   0.0  
gb|AAQ17531.1|  xanthine dehydrogenase [Drosophila eugracilis]   2135   0.0  
gb|AAQ17527.1|  xanthine dehydrogenase [Drosophila teissieri]    2133   0.0  
gb|AAQ17529.1|  xanthine dehydrogenase [Drosophila erecta]       2133   0.0  
gb|AAQ17528.1|  xanthine dehydrogenase [Drosophila yakuba]       2131   0.0  
gb|AAQ17533.1|  xanthine dehydrogenase [Drosophila lutescens]    2129   0.0  
gb|AAQ17530.1|  xanthine dehydrogenase [Drosophila orena]        2128   0.0  
gb|AAQ17532.1|  xanthine dehydrogenase [Drosophila mimetica]     2123   0.0  
ref|XP_001662131.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  2119   0.0  
ref|XP_001380730.1|  PREDICTED: similar to xanthine dehydrog...  2104   0.0  
ref|XP_001846124.1|  xanthine dehydrogenase [Culex pipiens q...  2097   0.0  
sp|P08793|XDH_CALVI  Xanthine dehydrogenase (XD)                 2081   0.0  
emb|CAP08999.1|  xanthine dehydrogenase [Lutzomyia longipalpis]  2081   0.0  
gb|AAG47345.1|  xanthine dehydrogenase [Ceratitis capitata]      2075   0.0  
dbj|BAA21640.1|  xanthine dehydrogenase [Bombyx mori]            2070   0.0  
gb|AAA27880.1|  xanthine dehydrogenase (AA at 2538)              2060   0.0  
emb|CAA30281.1|  xanthine dehydrogenase [Calliphora vicina]      2059   0.0  
ref|NP_001008419.1|  aldehyde oxidase 3-like 1 [Mus musculus...  2044   0.0  
ref|NP_001037325.1|  xanthine dehydrogenase [Bombyx mori] >g...  2044   0.0  
ref|XP_001606854.1|  PREDICTED: similar to aldehyde oxidase ...  2039   0.0  
ref|XP_001509432.1|  PREDICTED: similar to xanthine oxidored...  2038   0.0  
ref|XP_001370277.1|  PREDICTED: similar to aldehyde oxidase ...  2036   0.0  
ref|XP_610199.3|  PREDICTED: similar to aldehyde oxidase 3 [...  2035   0.0  
ref|NP_001041597.1|  aldehyde oxidase 3 [Canis lupus familia...  2034   0.0  
ref|XP_317568.3|  AGAP007918-PA [Anopheles gambiae str. PEST...  2034   0.0  
gb|AAL38126.1|  aldehyde oxidase structural homolog 2 [Mus m...  2021   0.0  
gb|AAI17977.1|  Aox4 protein [Mus musculus]                      2019   0.0  
ref|XP_001089327.1|  PREDICTED: similar to aldehyde oxidase ...  2018   0.0  
ref|NP_076120.2|  aldehyde oxidase 4 [Mus musculus] >gi|7415...  2018   0.0  
ref|XP_001500761.1|  PREDICTED: hypothetical protein [Equus ...  2015   0.0  
ref|XP_001379630.1|  PREDICTED: similar to aldehyde oxidase ...  2014   0.0  
ref|NP_001008522.1|  aldehyde oxidase 3-like 1 [Rattus norve...  2014   0.0  
ref|XP_001648863.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  2013   0.0  
ref|XP_001119950.1|  PREDICTED: similar to rosy CG7642-PA [A...  2012   0.0  
ref|NP_001008523.1|  aldehyde oxidase 4 [Rattus norvegicus] ...  2012   0.0  
ref|NP_788841.1|  aldehyde oxidase 1 [Bos taurus] >gi|170318...  2011   0.0  
ref|NP_001038214.1|  aldehyde oxidase 2 [Canis lupus familia...  2011   0.0  
ref|XP_001606866.1|  PREDICTED: similar to xanthine dehydrog...  2011   0.0  
gb|AAI05266.1|  Aldehyde oxidase 1 [Bos taurus]                  2011   0.0  
ref|XP_968229.1|  PREDICTED: similar to CG7642-PA [Tribolium...  2006   0.0  
ref|XP_001500709.1|  PREDICTED: hypothetical protein [Equus ...  2005   0.0  
ref|NP_001150.3|  aldehyde oxidase 1 [Homo sapiens] >gi|1351...  2005   0.0  
emb|CAH91253.1|  hypothetical protein [Pongo abelii]             2002   0.0  
sp|Q5FB27|ADO_MACFA  Aldehyde oxidase >gi|58737159|dbj|BAD89...  1998   0.0  
ref|XP_001089912.1|  PREDICTED: similar to aldehyde oxidase ...  1997   0.0  
gb|AAH26132.1|  Aldehyde oxidase 1 [Mus musculus]                1997   0.0  
gb|AAF98385.1|AF233581_1  aldehyde oxidase structural homolo...  1997   0.0  
gb|EAW70208.1|  aldehyde oxidase 1, isoform CRA_a [Homo sapi...  1994   0.0  
ref|NP_033806.2|  aldehyde oxidase 1 [Mus musculus] >gi|1486...  1994   0.0  
ref|XP_001503642.1|  PREDICTED: similar to aldehyde oxidase ...  1992   0.0  
dbj|BAA36834.1|  retinal oxidase/aldehyde oxidase [Mus muscu...  1991   0.0  
ref|XP_001379598.1|  PREDICTED: hypothetical protein [Monode...  1991   0.0  
gb|EDL99010.1|  aldehyde oxidase 1 [Rattus norvegicus]           1988   0.0  
gb|AAD31763.1|AF121945_1  aldehyde oxidase [Mus musculus]        1984   0.0  
sp|Q9Z0U5|ADO_RAT  Aldehyde oxidase >gi|4324710|gb|AAD16999....  1982   0.0  
ref|XP_596585.3|  PREDICTED: similar to aldehyde oxidase 2 [...  1981   0.0  
sp|O54754|ADO_MOUSE  Aldehyde oxidase (Retinal oxidase) >gi|...  1980   0.0  
ref|NP_062236.2|  aldehyde oxidase 1 [Rattus norvegicus] >gi...  1969   0.0  
ref|NP_001008527.1|  aldehyde oxidase 3 [Rattus norvegicus] ...  1967   0.0  
ref|NP_001075459.1|  retinal oxidase [Oryctolagus cuniculus]...  1963   0.0  
sp|Q06278|ADO_HUMAN  Aldehyde oxidase >gi|438656|gb|AAA96650...  1962   0.0  
gb|AAB83966.1|  aldehyde oxidase [Homo sapiens]                  1959   0.0  
ref|NP_001033781.1|  aldehyde oxidase 1 [Gallus gallus] >gi|...  1955   0.0  
ref|NP_001034690.1|  hypothetical protein LOC424072 [Gallus ...  1950   0.0  
ref|XP_699030.2|  PREDICTED: hypothetical protein [Danio rerio]  1948   0.0  
emb|CAK04754.2|  novel protein similar to vertebrate aldehyd...  1947   0.0  
gb|EDP50488.1|  xanthine dehydrogenase HxA, putative [Asperg...  1944   0.0  
gb|AAK59699.1|  xanthine dehydrogenase [Poecilia reticulata]     1942   0.0  
ref|XP_751707.1|  xanthine dehydrogenase HxA [Aspergillus fu...  1939   0.0  
ref|XP_001089798.1|  PREDICTED: similar to aldehyde oxidase ...  1938   0.0  
ref|XP_001266923.1|  xanthine dehydrogenase HxA, putative [N...  1936   0.0  
ref|XP_001247724.1|  hypothetical protein CIMG_01495 [Coccid...  1934   0.0  
gb|AAI38877.1|  Aldehyde oxidase 3 [Mus musculus]                1932   0.0  
ref|NP_076106.2|  aldehyde oxidase 3 [Mus musculus] >gi|1486...  1932   0.0  
gb|AAL36596.1|AF322178_1  AOH1 [Mus musculus]                    1930   0.0  
ref|XP_001271985.1|  xanthine dehydrogenase HxA, putative [A...  1929   0.0  
ref|XP_001379605.1|  PREDICTED: similar to aldehyde oxidase ...  1927   0.0  
gb|AAD51028.2|AF172276_1  aldehyde oxidase homolog-1 [Mus mu...  1917   0.0  
ref|XP_001820196.1|  hypothetical protein [Aspergillus oryza...  1915   0.0  
gb|AAO14865.1|  xanthine dehydrogenase [Anopheles gambiae]       1914   0.0  
ref|XP_001213137.1|  xanthine dehydrogenase [Aspergillus ter...  1913   0.0  
ref|XP_001401908.1|  hypothetical protein An04g05440 [Asperg...  1911   0.0  
gb|EDU48956.1|  xanthine dehydrogenase/oxidase [Pyrenophora ...  1908   0.0  
emb|CAA58034.1|  xanthine dehydrogenase [Emericella nidulans]    1905   0.0  
ref|XP_663217.1|  XDH_EMENI Xanthine dehydrogenase (Purine h...  1905   0.0  
gb|AAQ24538.1|  aldehyde oxidase 1 [Mus musculus]                1905   0.0  
gb|AAQ24537.1|  aldehyde oxidase 1 [Mus musculus]                1900   0.0  
ref|XP_782082.2|  PREDICTED: similar to xanthine dehydrogena...  1898   0.0  
ref|XP_001193570.1|  PREDICTED: similar to xanthine dehydrog...  1898   0.0  
dbj|BAB47183.1|  xanthine dehydrogenase [Bombyx mori]            1889   0.0  
ref|NP_001037333.1|  xanthine dehydrogenase [Bombyx mori] >g...  1887   0.0  
ref|XP_001225732.1|  hypothetical protein CHGG_08076 [Chaeto...  1875   0.0  
ref|XP_001544612.1|  xanthine dehydrogenase [Ajellomyces cap...  1868   0.0  
gb|EEH45510.1|  xanthine dehydrogenase [Paracoccidioides bra...  1866   0.0  
ref|XP_635420.1|  xanthine dehydrogenase [Dictyostelium disc...  1835   0.0  
emb|CAD37030.1|  probable xanthine dehydrogenase [Neurospora...  1831   0.0  
ref|XP_001909427.1|  unnamed protein product [Podospora anse...  1831   0.0  
ref|XP_956459.2|  xanthine dehydrogenase [Neurospora crassa ...  1829   0.0  
ref|XP_381737.1|  hypothetical protein FG01561.1 [Gibberella...  1828   0.0  
ref|NP_001050420.1|  Os03g0429800 [Oryza sativa (japonica cu...  1827   0.0  
ref|NP_195215.2|  ATXDH1 (XANTHINE DEHYDROGENASE 1); xanthin...  1827   0.0  
emb|CAB45450.1|  xanthine dehydrogenase-like protein [Arabid...  1825   0.0  
ref|XP_001669778.1|  Hypothetical protein CBG21624 [Caenorha...  1816   0.0  
emb|CAK04749.1|  novel protein similar to vertebrate xanthin...  1805   0.0  
ref|NP_502747.1|  F55B11.1 [Caenorhabditis elegans] >gi|3877...  1805   0.0  
gb|EAZ27415.1|  hypothetical protein OsJ_010898 [Oryza sativ...  1794   0.0  
ref|XP_001797843.1|  hypothetical protein SNOG_07509 [Phaeos...  1787   0.0  
ref|XP_001760766.1|  predicted protein [Physcomitrella paten...  1779   0.0  
ref|NP_195216.2|  xanthine dehydrogenase [Arabidopsis thaliana]  1776   0.0  
gb|AAR99079.1|  xanthine dehydrogenase 2 [Arabidopsis thaliana]  1776   0.0  
emb|CAO21923.1|  unnamed protein product [Vitis vinifera]        1768   0.0  
emb|CAB45451.1|  xanthine dehydrogenase [Arabidopsis thalian...  1765   0.0  
ref|NP_001086061.1|  MGC81880 protein [Xenopus laevis] >gi|4...  1755   0.0  
gb|EEH41343.1|  xanthine dehydrogenase [Paracoccidioides bra...  1752   0.0  
gb|ABF96752.1|  Aldehyde oxidase and xanthine dehydrogenase,...  1746   0.0  
ref|XP_001408466.1|  hypothetical protein MGG_12738 [Magnapo...  1740   0.0  
gb|EEH40664.1|  aldehyde oxidoreductase [Paracoccidioides br...  1735   0.0  
gb|EDL00071.1|  aldehyde oxidase 3-like 1 [Mus musculus]         1733   0.0  
ref|XP_001390055.1|  hypothetical protein An03g01530 [Asperg...  1722   0.0  
ref|XP_001261698.1|  xanthine dehydrogenase [Neosartorya fis...  1722   0.0  
gb|ACO65070.1|  predicted protein [Micromonas sp. RCC299]        1720   0.0  
gb|EDL99005.1|  rCG22451 [Rattus norvegicus]                     1707   0.0  
gb|EDL00069.1|  aldehyde oxidase 3, isoform CRA_b [Mus muscu...  1698   0.0  
ref|XP_682447.1|  hypothetical protein AN9178.2 [Aspergillus...  1688   0.0  
gb|EAY90548.1|  hypothetical protein OsI_011781 [Oryza sativ...  1688   0.0  
ref|XP_001558086.1|  hypothetical protein BC1G_03118 [Botryo...  1683   0.0  
gb|EDU50617.1|  xanthine dehydrogenase/oxidase [Pyrenophora ...  1672   0.0  
ref|XP_001794615.1|  hypothetical protein SNOG_04191 [Phaeos...  1668   0.0  
ref|XP_759411.1|  hypothetical protein UM03264.1 [Ustilago m...  1660   0.0  
ref|XP_001307869.1|  aldehyde oxidase and xanthine dehydroge...  1648   0.0  
ref|XP_001539262.1|  xanthine dehydrogenase [Ajellomyces cap...  1646   0.0  
ref|XP_001217202.1|  xanthine dehydrogenase [Aspergillus ter...  1621   0.0  
ref|XP_001515925.1|  PREDICTED: similar to xanthine dehydrog...  1615   0.0  
dbj|BAA21639.1|  xanthine dehydrogenase [Bombyx mori]            1611   0.0  
ref|XP_001864334.1|  aldehyde oxidase [Culex pipiens quinque...  1605   0.0  
ref|XP_001305898.1|  aldehyde oxidase and xanthine dehydroge...  1600   0.0  
ref|XP_001590688.1|  hypothetical protein SS1G_08428 [Sclero...  1597   0.0  
ref|XP_001864348.1|  xanthine dehydrogenase/oxidase [Culex p...  1591   0.0  
ref|XP_001864336.1|  xanthine dehydrogenase/oxidase [Culex p...  1578   0.0  
ref|XP_001654513.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1566   0.0  
gb|EEH50118.1|  xanthine dehydrogenase [Paracoccidioides bra...  1560   0.0  
ref|XP_001182218.1|  PREDICTED: similar to xanthine:oxygen o...  1550   0.0  
ref|YP_631346.1|  putative xanthine dehydrogenase [Myxococcu...  1538   0.0  
ref|XP_790508.2|  PREDICTED: similar to xanthine:oxygen oxid...  1534   0.0  
dbj|BAB47182.1|  truncated xanthine dehydrogenase [Bombyx mori]  1531   0.0  
ref|XP_001654511.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1527   0.0  
ref|XP_316291.4|  AGAP006225-PA [Anopheles gambiae str. PEST...  1525   0.0  
ref|XP_001694090.1|  xanthine dehydrogenase/oxidase [Chlamyd...  1514   0.0  
ref|XP_001662405.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1507   0.0  
ref|XP_001654510.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1504   0.0  
ref|ZP_02970663.1|  aldehyde oxidase and xanthine dehydrogen...  1500   0.0  
ref|XP_001625891.1|  predicted protein [Nematostella vectens...  1498   0.0  
gb|AAF87601.1|  aldehyde oxidase [Culex pipiens quinquefasci...  1494   0.0  
ref|XP_793571.2|  PREDICTED: similar to xanthine dehydrogena...  1491   0.0  
ref|XP_001654512.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1487   0.0  
ref|XP_001864335.1|  aldehyde oxidase [Culex pipiens quinque...  1487   0.0  
ref|XP_001654494.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1477   0.0  
ref|XP_316294.4|  AGAP006226-PA [Anopheles gambiae str. PEST...  1476   0.0  
gb|AAG22607.1|AF258810_1  aldehyde oxidase [Lycopersicon esc...  1474   0.0  
emb|CAN64116.1|  hypothetical protein [Vitis vinifera]           1471   0.0  
ref|NP_189946.1|  AAO2 (ALDEHYDE OXIDASE 2) [Arabidopsis tha...  1471   0.0  
ref|NP_563711.1|  AAO4 (ALDEHYDE OXIDASE 4); aldehyde oxidas...  1471   0.0  
emb|CAO16331.1|  unnamed protein product [Vitis vinifera]        1466   0.0  
ref|XP_001868138.1|  xanthine dehydrogenase [Culex pipiens q...  1466   0.0  
ref|XP_001688833.1|  AGAP006224-PA [Anopheles gambiae str. P...  1461   0.0  
ref|XP_001654495.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1460   0.0  
ref|NP_001051517.1|  Os03g0790700 [Oryza sativa (japonica cu...  1457   0.0  
ref|XP_001868139.1|  xanthine dehydrogenase/oxidase [Culex p...  1456   0.0  
ref|NP_001051518.1|  Os03g0790900 [Oryza sativa (japonica cu...  1450   0.0  
sp|Q852M1|ALDO2_ORYSJ  Probable aldehyde oxidase 2 (AO-2) >g...  1450   0.0  
ref|NP_001064133.1|  Os10g0138100 [Oryza sativa (japonica cu...  1449   0.0  
emb|CAN75890.1|  hypothetical protein [Vitis vinifera]           1449   0.0  
sp|Q7XH05|ALDO1_ORYSJ  Probable aldehyde oxidase 1 (AO-1) >g...  1449   0.0  
ref|NP_851049.1|  AAO1 (ALDEHYDE OXIDASE 1) [Arabidopsis tha...  1449   0.0  
ref|XP_001866986.1|  xanthine dehydrogenase/oxidase [Culex p...  1445   0.0  
ref|NP_001105308.1|  aldehyde oxidase [Zea mays] >gi|2589162...  1443   0.0  
emb|CAO67442.1|  unnamed protein product [Vitis vinifera]        1439   0.0  
gb|ABS32108.1|  aldehyde oxidase 1 [Pisum sativum]               1438   0.0  
gb|AAG22606.1|AF258809_1  aldehyde oxidase [Lycopersicon esc...  1437   0.0  
gb|AAC39509.1|  putative aldehyde oxidase [Arabidopsis thali...  1436   0.0  
dbj|BAA82672.1|  aldehyde oxidase [Arabidopsis thaliana]         1436   0.0  
ref|NP_180283.1|  AAO3 (ABSCISIC ALDEHYDE OXIDASE 3) [Arabid...  1435   0.0  
ref|XP_001845789.1|  aldehyde oxidase [Culex pipiens quinque...  1434   0.0  
ref|NP_001105309.1|  aldehyde oxidase-2 [Zea mays] >gi|25891...  1431   0.0  
gb|EAY77650.1|  hypothetical protein OsI_031609 [Oryza sativ...  1426   0.0  
ref|XP_001864333.1|  xanthine dehydrogenase/oxidase [Culex p...  1425   0.0  
ref|XP_001657559.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1421   0.0  
dbj|BAE93768.1|  aldehyde oxidase [Brassica rapa subsp. peki...  1420   0.0  
gb|ABS32110.1|  aldehyde oxidase 3 [Pisum sativum]               1419   0.0  
dbj|BAB23485.1|  unnamed protein product [Mus musculus]          1414   0.0  
ref|XP_001657560.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1413   0.0  
dbj|BAC79746.1|  putative aldehyde oxidase [Oryza sativa Jap...  1411   0.0  
dbj|BAE93767.1|  aldehyde oxidase [Brassica rapa subsp. peki...  1410   0.0  
gb|AAG22605.1|AF258808_1  aldehyde oxidase [Lycopersicon esc...  1410   0.0  
ref|XP_001688700.1|  AGAP005637-PA [Anopheles gambiae str. P...  1409   0.0  
gb|ABS32109.1|  aldehyde oxidase 2 [Pisum sativum]               1404   0.0  
gb|EAZ39412.1|  hypothetical protein OsJ_022895 [Oryza sativ...  1400   0.0  
ref|XP_688983.2|  PREDICTED: similar to xanthine dehydrogena...  1400   0.0  
gb|EAZ03500.1|  hypothetical protein OsI_024732 [Oryza sativ...  1397   0.0  
pdb|1FIQ|C  Chain C, Crystal Structure Of Xanthine Oxidase F...  1396   0.0  
ref|XP_001606247.1|  PREDICTED: similar to aldehyde oxidase ...  1384   0.0  
gb|AAO41437.1|  RE51958p [Drosophila melanogaster]               1382   0.0  
ref|NP_650477.1|  CG6045 CG6045-PA [Drosophila melanogaster]...  1382   0.0  
sp|Q6Z351|ALDOL_ORYSJ  Putative aldehyde oxidase-like protei...  1375   0.0  
dbj|BAE72098.1|  Lactuca sativa aldehyde oxidase 1               1374   0.0  
ref|XP_001326092.1|  aldehyde oxidase and xanthine dehydroge...  1368   0.0  
ref|XP_001866985.1|  aldehyde oxidase 2 [Culex pipiens quinq...  1363   0.0  
ref|XP_001360071.1|  GA14972-PA [Drosophila pseudoobscura] >...  1362   0.0  
ref|NP_650475.1|  CG18522 CG18522-PA [Drosophila melanogaste...  1357   0.0  
ref|XP_001360072.1|  GA19318-PA [Drosophila pseudoobscura] >...  1354   0.0  
ref|XP_967707.1|  PREDICTED: similar to CG6045-PA [Tribolium...  1349   0.0  
ref|XP_001637029.1|  predicted protein [Nematostella vectens...  1346   0.0  
gb|AAY24265.1|  unknown [Homo sapiens]                           1345   0.0  
ref|XP_001654493.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1338   0.0  
ref|XP_968525.1|  PREDICTED: similar to CG18522-PA [Triboliu...  1337   0.0  
ref|XP_001584737.1|  hypothetical protein SS1G_14350 [Sclero...  1334   0.0  
ref|XP_001603962.1|  PREDICTED: similar to aldehyde oxidase ...  1332   0.0  
ref|XP_001509402.1|  PREDICTED: similar to xanthine dehydrog...  1320   0.0  
ref|NP_732047.1|  CG18519 CG18519-PB, isoform B [Drosophila ...  1320   0.0  
ref|NP_001103811.1|  aldehyde oxidase 2 [Bombyx mori] >gi|15...  1319   0.0  
gb|EDL38419.1|  xanthine dehydrogenase, isoform CRA_c [Mus m...  1314   0.0  
ref|XP_001782658.1|  predicted protein [Physcomitrella paten...  1308   0.0  
ref|XP_001767396.1|  predicted protein [Physcomitrella paten...  1302   0.0  
gb|EAZ38800.1|  hypothetical protein OsJ_022283 [Oryza sativ...  1284   0.0  
gb|EAY92133.1|  hypothetical protein OsI_013366 [Oryza sativ...  1276   0.0  
gb|AAM11042.1|  GH08847p [Drosophila melanogaster]               1274   0.0  
gb|AAB41742.1|  aldehyde oxidase 1 homolog [Lycopersicon esc...  1259   0.0  
ref|XP_001773979.1|  predicted protein [Physcomitrella paten...  1250   0.0  
gb|EAZ03503.1|  hypothetical protein OsI_024735 [Oryza sativ...  1220   0.0  
gb|EAW70211.1|  hCG1811467 [Homo sapiens]                        1217   0.0  
ref|NP_505377.2|  B0222.9 [Caenorhabditis elegans] >gi|26251...  1208   0.0  
emb|CAO16329.1|  unnamed protein product [Vitis vinifera]        1203   0.0  
ref|NP_500531.1|  F15E6.6 [Caenorhabditis elegans] >gi|14574...  1193   0.0  
gb|AAX13175.1|  rosy [Drosophila miranda]                        1189   0.0  
gb|AAX13168.1|  rosy [Drosophila miranda] >gi|60100070|gb|AA...  1189   0.0  
gb|AAX13174.1|  rosy [Drosophila miranda]                        1189   0.0  
gb|AAX13179.1|  rosy [Drosophila miranda]                        1189   0.0  
gb|AAX13171.1|  rosy [Drosophila miranda]                        1188   0.0  
gb|AAX13176.1|  rosy [Drosophila miranda] >gi|60100086|gb|AA...  1188   0.0  
gb|AAX13170.1|  rosy [Drosophila miranda] >gi|60100076|gb|AA...  1187   0.0  
gb|AAX13180.1|  rosy [Drosophila pseudoobscura]                  1187   0.0  
ref|ZP_02009720.1|  aldehyde oxidase and xanthine dehydrogen...  1187   0.0  
gb|AAX13167.1|  rosy [Drosophila affinis]                        1186   0.0  
ref|YP_001899813.1|  xanthine dehydrogenase, molybdopterin b...  1186   0.0  
gb|AAX13173.1|  rosy [Drosophila miranda]                        1185   0.0  
ref|YP_296632.1|  Xanthine dehydrogenase [Ralstonia eutropha...  1182   0.0  
gb|AAW31602.1|  xanthine dehydrogenase [Drosophila bifurca]      1175   0.0  
ref|XP_001625969.1|  predicted protein [Nematostella vectens...  1174   0.0  
ref|XP_001497159.1|  PREDICTED: similar to aldehyde oxidase ...  1173   0.0  
gb|EDL00070.1|  aldehyde oxidase 4 [Mus musculus]                1169   0.0  
Sequences not found previously or not previously below threshold:

gb|AAB80640.1|  Strong similarity to Lycopersicon aldehyde o...  1449   0.0  
ref|XP_315656.4|  AGAP005638-PA [Anopheles gambiae str. PEST...  1348   0.0  
ref|XP_315654.3|  AGAP005636-PA [Anopheles gambiae str. PEST...  1330   0.0  
ref|XP_001688831.1|  AGAP006221-PA [Anopheles gambiae str. P...  1328   0.0  
ref|XP_001360073.1|  GA14970-PA [Drosophila pseudoobscura] >...  1319   0.0  
ref|NP_650478.1|  CG18516 CG18516-PA [Drosophila melanogaste...  1304   0.0  
ref|NP_650476.1|  CG18519 CG18519-PA, isoform A [Drosophila ...  1273   0.0  
ref|NP_001103812.1|  aldehyde oxidase 1 [Bombyx mori] >gi|15...  1265   0.0  
ref|XP_001360074.1|  GA14971-PA [Drosophila pseudoobscura] >...  1231   0.0  
gb|EAY92132.1|  hypothetical protein OsI_013365 [Oryza sativ...  1199   0.0  
Searching..................................................done Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

gb|AAA75287.1|  xanthine dehydrogenase                           2302   0.0  
ref|NP_000370.2|  xanthine dehydrogenase [Homo sapiens] >gi|...  2291   0.0  
ref|XP_525729.2|  PREDICTED: xanthine dehydrogenase [Pan tro...  2290   0.0  
pdb|2E1Q|A  Chain A, Crystal Structure Of Human Xanthine Oxi...  2289   0.0  
ref|XP_001501608.1|  PREDICTED: similar to xanthine dehydrog...  2286   0.0  
ref|NP_001009217.1|  xanthine dehydrogenase [Felis catus] >g...  2270   0.0  
gb|ABL96618.1|  xanthine oxidoreductase [Capra hircus]           2265   0.0  
gb|AAI41184.1|  Xanthine dehydrogenase [Mus musculus]            2265   0.0  
ref|NP_001116410.1|  xanthine dehydrogenase/oxidase [Oryctol...  2264   0.0  
ref|NP_035853.2|  xanthine dehydrogenase [Mus musculus]          2263   0.0  
sp|Q00519|XDH_MOUSE  Xanthine dehydrogenase/oxidase [Include...  2263   0.0  
gb|EDL38417.1|  xanthine dehydrogenase, isoform CRA_a [Mus m...  2263   0.0  
dbj|BAE26022.1|  unnamed protein product [Mus musculus]          2261   0.0  
emb|CAA44705.1|  xanthine dehydrogenase [Mus musculus]           2259   0.0  
ref|XP_862631.1|  PREDICTED: similar to Xanthine dehydrogena...  2258   0.0  
ref|XP_540143.2|  PREDICTED: similar to Xanthine dehydrogena...  2258   0.0  
gb|EDM02851.1|  rCG61833 [Rattus norvegicus]                     2257   0.0  
ref|XP_862539.1|  PREDICTED: similar to Xanthine dehydrogena...  2256   0.0  
ref|XP_862684.1|  PREDICTED: similar to Xanthine dehydrogena...  2255   0.0  
ref|NP_990458.1|  xanthine dehydrogenase [Gallus gallus] >gi...  2254   0.0  
ref|NP_058850.1|  xanthine dehydrogenase [Rattus norvegicus]...  2253   0.0  
ref|XP_001501696.1|  PREDICTED: similar to xanthine dehydrog...  2251   0.0  
sp|P80457|XDH_BOVIN  Xanthine dehydrogenase/oxidase [Include...  2250   0.0  
pdb|1WYG|A  Chain A, Crystal Structure Of A Rat Xanthine Deh...  2249   0.0  
ref|NP_776397.1|  xanthine dehydrogenase [Bos taurus] >gi|11...  2249   0.0  
gb|AAD17938.1|  xanthine:oxygen oxidoreductase [Tragelaphus ...  2246   0.0  
pdb|2E3T|A  Chain A, Crystal Structure Of Rat Xanthine Oxido...  2246   0.0  
pdb|1N5X|A  Chain A, Xanthine Dehydrogenase From Bovine Milk...  2246   0.0  
ref|XP_862565.1|  PREDICTED: similar to Xanthine dehydrogena...  2243   0.0  
ref|XP_862658.1|  PREDICTED: similar to Xanthine dehydrogena...  2243   0.0  
gb|AAD17937.1|  xanthine:oxygen oxidoreductase [Syncerus caf...  2228   0.0  
emb|CAA67117.1|  xanthine dehydrogenase [Bos taurus]             2225   0.0  
ref|XP_862593.1|  PREDICTED: similar to Xanthine dehydrogena...  2214   0.0  
ref|XP_862613.1|  PREDICTED: similar to Xanthine dehydrogena...  2205   0.0  
ref|NP_524337.1|  rosy CG7642-PA [Drosophila melanogaster] >...  2199   0.0  
emb|CAA68409.1|  xanthine dehydrogenase [Drosophila melanoga...  2191   0.0  
sp|P22811|XDH_DROPS  Xanthine dehydrogenase (XD) (Protein ro...  2180   0.0  
ref|XP_001358503.1|  GA20500-PA [Drosophila pseudoobscura] >...  2179   0.0  
gb|AAQ17526.1|  xanthine dehydrogenase [Drosophila simulans]     2172   0.0  
sp|P91711|XDH_DROSU  Xanthine dehydrogenase (XD) (Protein ro...  2172   0.0  
ref|XP_001662131.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  2168   0.0  
gb|AAA29022.1|  xanthine dehydrogenase (Xdh)                     2167   0.0  
gb|AAQ17527.1|  xanthine dehydrogenase [Drosophila teissieri]    2162   0.0  
gb|AAQ17531.1|  xanthine dehydrogenase [Drosophila eugracilis]   2160   0.0  
gb|AAQ17528.1|  xanthine dehydrogenase [Drosophila yakuba]       2158   0.0  
gb|AAQ17529.1|  xanthine dehydrogenase [Drosophila erecta]       2157   0.0  
gb|AAQ17533.1|  xanthine dehydrogenase [Drosophila lutescens]    2155   0.0  
gb|AAQ17530.1|  xanthine dehydrogenase [Drosophila orena]        2153   0.0  
gb|AAQ17532.1|  xanthine dehydrogenase [Drosophila mimetica]     2152   0.0  
ref|XP_001846124.1|  xanthine dehydrogenase [Culex pipiens q...  2141   0.0  
dbj|BAA21640.1|  xanthine dehydrogenase [Bombyx mori]            2116   0.0  
emb|CAP08999.1|  xanthine dehydrogenase [Lutzomyia longipalpis]  2115   0.0  
sp|P08793|XDH_CALVI  Xanthine dehydrogenase (XD)                 2114   0.0  
ref|XP_001380730.1|  PREDICTED: similar to xanthine dehydrog...  2106   0.0  
gb|AAG47345.1|  xanthine dehydrogenase [Ceratitis capitata]      2101   0.0  
gb|AAA27880.1|  xanthine dehydrogenase (AA at 2538)              2092   0.0  
ref|NP_001037325.1|  xanthine dehydrogenase [Bombyx mori] >g...  2091   0.0  
emb|CAA30281.1|  xanthine dehydrogenase [Calliphora vicina]      2091   0.0  
ref|XP_001606854.1|  PREDICTED: similar to aldehyde oxidase ...  2082   0.0  
ref|XP_317568.3|  AGAP007918-PA [Anopheles gambiae str. PEST...  2077   0.0  
ref|XP_001370277.1|  PREDICTED: similar to aldehyde oxidase ...  2064   0.0  
ref|XP_001648863.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  2063   0.0  
ref|XP_001119950.1|  PREDICTED: similar to rosy CG7642-PA [A...  2061   0.0  
ref|NP_001008419.1|  aldehyde oxidase 3-like 1 [Mus musculus...  2060   0.0  
ref|XP_001606866.1|  PREDICTED: similar to xanthine dehydrog...  2056   0.0  
ref|XP_610199.3|  PREDICTED: similar to aldehyde oxidase 3 [...  2054   0.0  
gb|AAL38126.1|  aldehyde oxidase structural homolog 2 [Mus m...  2054   0.0  
ref|NP_001041597.1|  aldehyde oxidase 3 [Canis lupus familia...  2052   0.0  
gb|AAI17977.1|  Aox4 protein [Mus musculus]                      2052   0.0  
ref|NP_076120.2|  aldehyde oxidase 4 [Mus musculus] >gi|7415...  2051   0.0  
ref|XP_968229.1|  PREDICTED: similar to CG7642-PA [Tribolium...  2046   0.0  
ref|NP_788841.1|  aldehyde oxidase 1 [Bos taurus] >gi|170318...  2046   0.0  
ref|XP_001500761.1|  PREDICTED: hypothetical protein [Equus ...  2045   0.0  
ref|XP_001509432.1|  PREDICTED: similar to xanthine oxidored...  2045   0.0  
gb|AAI05266.1|  Aldehyde oxidase 1 [Bos taurus]                  2045   0.0  
ref|NP_001008523.1|  aldehyde oxidase 4 [Rattus norvegicus] ...  2042   0.0  
ref|XP_001089327.1|  PREDICTED: similar to aldehyde oxidase ...  2041   0.0  
ref|NP_001038214.1|  aldehyde oxidase 2 [Canis lupus familia...  2037   0.0  
ref|XP_001500709.1|  PREDICTED: hypothetical protein [Equus ...  2037   0.0  
ref|XP_001379630.1|  PREDICTED: similar to aldehyde oxidase ...  2037   0.0  
ref|NP_001008522.1|  aldehyde oxidase 3-like 1 [Rattus norve...  2032   0.0  
ref|NP_001150.3|  aldehyde oxidase 1 [Homo sapiens] >gi|1351...  2030   0.0  
gb|AAH26132.1|  Aldehyde oxidase 1 [Mus musculus]                2027   0.0  
gb|AAF98385.1|AF233581_1  aldehyde oxidase structural homolo...  2027   0.0  
emb|CAH91253.1|  hypothetical protein [Pongo abelii]             2026   0.0  
ref|NP_033806.2|  aldehyde oxidase 1 [Mus musculus] >gi|1486...  2025   0.0  
dbj|BAA36834.1|  retinal oxidase/aldehyde oxidase [Mus muscu...  2022   0.0  
sp|Q5FB27|ADO_MACFA  Aldehyde oxidase >gi|58737159|dbj|BAD89...  2021   0.0  
gb|EAW70208.1|  aldehyde oxidase 1, isoform CRA_a [Homo sapi...  2021   0.0  
ref|XP_001089912.1|  PREDICTED: similar to aldehyde oxidase ...  2020   0.0  
ref|XP_001379598.1|  PREDICTED: hypothetical protein [Monode...  2019   0.0  
gb|EDL99010.1|  aldehyde oxidase 1 [Rattus norvegicus]           2018   0.0  
ref|XP_001503642.1|  PREDICTED: similar to aldehyde oxidase ...  2015   0.0  
gb|AAD31763.1|AF121945_1  aldehyde oxidase [Mus musculus]        2014   0.0  
sp|Q9Z0U5|ADO_RAT  Aldehyde oxidase >gi|4324710|gb|AAD16999....  2011   0.0  
ref|XP_596585.3|  PREDICTED: similar to aldehyde oxidase 2 [...  2010   0.0  
sp|O54754|ADO_MOUSE  Aldehyde oxidase (Retinal oxidase) >gi|...  2010   0.0  
ref|NP_001008527.1|  aldehyde oxidase 3 [Rattus norvegicus] ...  2006   0.0  
gb|EDP50488.1|  xanthine dehydrogenase HxA, putative [Asperg...  2002   0.0  
ref|NP_001075459.1|  retinal oxidase [Oryctolagus cuniculus]...  2001   0.0  
ref|NP_062236.2|  aldehyde oxidase 1 [Rattus norvegicus] >gi...  1998   0.0  
ref|XP_001266923.1|  xanthine dehydrogenase HxA, putative [N...  1997   0.0  
ref|XP_751707.1|  xanthine dehydrogenase HxA [Aspergillus fu...  1997   0.0  
ref|XP_699030.2|  PREDICTED: hypothetical protein [Danio rerio]  1989   0.0  
ref|XP_001247724.1|  hypothetical protein CIMG_01495 [Coccid...  1987   0.0  
ref|XP_001271985.1|  xanthine dehydrogenase HxA, putative [A...  1987   0.0  
ref|NP_001033781.1|  aldehyde oxidase 1 [Gallus gallus] >gi|...  1986   0.0  
emb|CAK04754.2|  novel protein similar to vertebrate aldehyd...  1985   0.0  
sp|Q06278|ADO_HUMAN  Aldehyde oxidase >gi|438656|gb|AAA96650...  1983   0.0  
gb|AAB83966.1|  aldehyde oxidase [Homo sapiens]                  1980   0.0  
ref|XP_001213137.1|  xanthine dehydrogenase [Aspergillus ter...  1977   0.0  
ref|XP_001401908.1|  hypothetical protein An04g05440 [Asperg...  1976   0.0  
ref|NP_076106.2|  aldehyde oxidase 3 [Mus musculus] >gi|1486...  1974   0.0  
gb|AAI38877.1|  Aldehyde oxidase 3 [Mus musculus]                1974   0.0  
ref|NP_001034690.1|  hypothetical protein LOC424072 [Gallus ...  1974   0.0  
ref|XP_001820196.1|  hypothetical protein [Aspergillus oryza...  1973   0.0  
gb|AAK59699.1|  xanthine dehydrogenase [Poecilia reticulata]     1972   0.0  
emb|CAA58034.1|  xanthine dehydrogenase [Emericella nidulans]    1972   0.0  
ref|XP_663217.1|  XDH_EMENI Xanthine dehydrogenase (Purine h...  1971   0.0  
gb|AAL36596.1|AF322178_1  AOH1 [Mus musculus]                    1971   0.0  
gb|EDU48956.1|  xanthine dehydrogenase/oxidase [Pyrenophora ...  1970   0.0  
ref|XP_001379605.1|  PREDICTED: similar to aldehyde oxidase ...  1963   0.0  
ref|XP_001089798.1|  PREDICTED: similar to aldehyde oxidase ...  1962   0.0  
gb|AAD51028.2|AF172276_1  aldehyde oxidase homolog-1 [Mus mu...  1957   0.0  
ref|XP_001225732.1|  hypothetical protein CHGG_08076 [Chaeto...  1948   0.0  
gb|AAQ24538.1|  aldehyde oxidase 1 [Mus musculus]                1945   0.0  
gb|AAQ24537.1|  aldehyde oxidase 1 [Mus musculus]                1940   0.0  
gb|AAO14865.1|  xanthine dehydrogenase [Anopheles gambiae]       1938   0.0  
ref|XP_001193570.1|  PREDICTED: similar to xanthine dehydrog...  1937   0.0  
ref|XP_782082.2|  PREDICTED: similar to xanthine dehydrogena...  1936   0.0  
ref|XP_001544612.1|  xanthine dehydrogenase [Ajellomyces cap...  1925   0.0  
dbj|BAB47183.1|  xanthine dehydrogenase [Bombyx mori]            1923   0.0  
ref|NP_001037333.1|  xanthine dehydrogenase [Bombyx mori] >g...  1919   0.0  
gb|EEH45510.1|  xanthine dehydrogenase [Paracoccidioides bra...  1915   0.0  
emb|CAD37030.1|  probable xanthine dehydrogenase [Neurospora...  1899   0.0  
ref|NP_001050420.1|  Os03g0429800 [Oryza sativa (japonica cu...  1898   0.0  
ref|XP_956459.2|  xanthine dehydrogenase [Neurospora crassa ...  1896   0.0  
ref|XP_001909427.1|  unnamed protein product [Podospora anse...  1891   0.0  
ref|XP_381737.1|  hypothetical protein FG01561.1 [Gibberella...  1887   0.0  
ref|NP_195215.2|  ATXDH1 (XANTHINE DEHYDROGENASE 1); xanthin...  1870   0.0  
emb|CAB45450.1|  xanthine dehydrogenase-like protein [Arabid...  1868   0.0  
ref|XP_001669778.1|  Hypothetical protein CBG21624 [Caenorha...  1867   0.0  
gb|EAZ27415.1|  hypothetical protein OsJ_010898 [Oryza sativ...  1864   0.0  
ref|XP_635420.1|  xanthine dehydrogenase [Dictyostelium disc...  1863   0.0  
ref|NP_502747.1|  F55B11.1 [Caenorhabditis elegans] >gi|3877...  1858   0.0  
emb|CAK04749.1|  novel protein similar to vertebrate xanthin...  1836   0.0  
emb|CAO21923.1|  unnamed protein product [Vitis vinifera]        1823   0.0  
ref|NP_195216.2|  xanthine dehydrogenase [Arabidopsis thaliana]  1823   0.0  
gb|AAR99079.1|  xanthine dehydrogenase 2 [Arabidopsis thaliana]  1822   0.0  
ref|XP_001760766.1|  predicted protein [Physcomitrella paten...  1815   0.0  
ref|XP_001797843.1|  hypothetical protein SNOG_07509 [Phaeos...  1814   0.0  
gb|ABF96752.1|  Aldehyde oxidase and xanthine dehydrogenase,...  1812   0.0  
emb|CAB45451.1|  xanthine dehydrogenase [Arabidopsis thalian...  1811   0.0  
gb|EEH41343.1|  xanthine dehydrogenase [Paracoccidioides bra...  1807   0.0  
ref|XP_001390055.1|  hypothetical protein An03g01530 [Asperg...  1793   0.0  
ref|XP_001408466.1|  hypothetical protein MGG_12738 [Magnapo...  1791   0.0  
ref|XP_001261698.1|  xanthine dehydrogenase [Neosartorya fis...  1787   0.0  
gb|EEH40664.1|  aldehyde oxidoreductase [Paracoccidioides br...  1776   0.0  
ref|NP_001086061.1|  MGC81880 protein [Xenopus laevis] >gi|4...  1766   0.0  
gb|EAY90548.1|  hypothetical protein OsI_011781 [Oryza sativ...  1759   0.0  
gb|ACO65070.1|  predicted protein [Micromonas sp. RCC299]        1757   0.0  
gb|EDL00071.1|  aldehyde oxidase 3-like 1 [Mus musculus]         1742   0.0  
ref|XP_001794615.1|  hypothetical protein SNOG_04191 [Phaeos...  1735   0.0  
ref|XP_001558086.1|  hypothetical protein BC1G_03118 [Botryo...  1730   0.0  
ref|XP_682447.1|  hypothetical protein AN9178.2 [Aspergillus...  1730   0.0  
gb|EDU50617.1|  xanthine dehydrogenase/oxidase [Pyrenophora ...  1728   0.0  
gb|EDL00069.1|  aldehyde oxidase 3, isoform CRA_b [Mus muscu...  1721   0.0  
gb|EDL99005.1|  rCG22451 [Rattus norvegicus]                     1719   0.0  
ref|XP_759411.1|  hypothetical protein UM03264.1 [Ustilago m...  1702   0.0  
ref|XP_001539262.1|  xanthine dehydrogenase [Ajellomyces cap...  1697   0.0  
ref|XP_001864334.1|  aldehyde oxidase [Culex pipiens quinque...  1688   0.0  
ref|XP_001307869.1|  aldehyde oxidase and xanthine dehydroge...  1685   0.0  
ref|XP_001217202.1|  xanthine dehydrogenase [Aspergillus ter...  1674   0.0  
ref|XP_001864348.1|  xanthine dehydrogenase/oxidase [Culex p...  1672   0.0  
ref|XP_001864336.1|  xanthine dehydrogenase/oxidase [Culex p...  1662   0.0  
ref|XP_001590688.1|  hypothetical protein SS1G_08428 [Sclero...  1654   0.0  
ref|XP_001654513.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1650   0.0  
ref|XP_001515925.1|  PREDICTED: similar to xanthine dehydrog...  1632   0.0  
ref|XP_001305898.1|  aldehyde oxidase and xanthine dehydroge...  1628   0.0  
dbj|BAA21639.1|  xanthine dehydrogenase [Bombyx mori]            1613   0.0  
ref|XP_316291.4|  AGAP006225-PA [Anopheles gambiae str. PEST...  1609   0.0  
ref|XP_001654511.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1596   0.0  
gb|EEH50118.1|  xanthine dehydrogenase [Paracoccidioides bra...  1591   0.0  
ref|XP_001662405.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1589   0.0  
dbj|BAB47182.1|  truncated xanthine dehydrogenase [Bombyx mori]  1582   0.0  
ref|XP_001182218.1|  PREDICTED: similar to xanthine:oxygen o...  1575   0.0  
ref|XP_001654510.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1574   0.0  
gb|AAF87601.1|  aldehyde oxidase [Culex pipiens quinquefasci...  1573   0.0  
ref|XP_001864335.1|  aldehyde oxidase [Culex pipiens quinque...  1564   0.0  
ref|XP_001654494.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1563   0.0  
ref|XP_790508.2|  PREDICTED: similar to xanthine:oxygen oxid...  1557   0.0  
ref|XP_001654512.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1556   0.0  
emb|CAN64116.1|  hypothetical protein [Vitis vinifera]           1547   0.0  
ref|XP_316294.4|  AGAP006226-PA [Anopheles gambiae str. PEST...  1547   0.0  
ref|YP_631346.1|  putative xanthine dehydrogenase [Myxococcu...  1546   0.0  
ref|XP_001868138.1|  xanthine dehydrogenase [Culex pipiens q...  1544   0.0  
gb|AAG22607.1|AF258810_1  aldehyde oxidase [Lycopersicon esc...  1542   0.0  
ref|NP_189946.1|  AAO2 (ALDEHYDE OXIDASE 2) [Arabidopsis tha...  1538   0.0  
ref|XP_001694090.1|  xanthine dehydrogenase/oxidase [Chlamyd...  1537   0.0  
ref|XP_001868139.1|  xanthine dehydrogenase/oxidase [Culex p...  1535   0.0  
ref|NP_001051517.1|  Os03g0790700 [Oryza sativa (japonica cu...  1535   0.0  
ref|XP_001654495.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1534   0.0  
ref|NP_563711.1|  AAO4 (ALDEHYDE OXIDASE 4); aldehyde oxidas...  1534   0.0  
ref|XP_001688833.1|  AGAP006224-PA [Anopheles gambiae str. P...  1530   0.0  
sp|Q852M1|ALDO2_ORYSJ  Probable aldehyde oxidase 2 (AO-2) >g...  1526   0.0  
ref|NP_001051518.1|  Os03g0790900 [Oryza sativa (japonica cu...  1526   0.0  
ref|XP_001866986.1|  xanthine dehydrogenase/oxidase [Culex p...  1526   0.0  
emb|CAO16331.1|  unnamed protein product [Vitis vinifera]        1522   0.0  
ref|XP_001625891.1|  predicted protein [Nematostella vectens...  1521   0.0  
ref|ZP_02970663.1|  aldehyde oxidase and xanthine dehydrogen...  1516   0.0  
gb|AAB80640.1|  Strong similarity to Lycopersicon aldehyde o...  1514   0.0  
ref|NP_001064133.1|  Os10g0138100 [Oryza sativa (japonica cu...  1512   0.0  
sp|Q7XH05|ALDO1_ORYSJ  Probable aldehyde oxidase 1 (AO-1) >g...  1512   0.0  
emb|CAN75890.1|  hypothetical protein [Vitis vinifera]           1512   0.0  
gb|AAG22606.1|AF258809_1  aldehyde oxidase [Lycopersicon esc...  1506   0.0  
ref|NP_851049.1|  AAO1 (ALDEHYDE OXIDASE 1) [Arabidopsis tha...  1502   0.0  
ref|NP_001105308.1|  aldehyde oxidase [Zea mays] >gi|2589162...  1501   0.0  
dbj|BAA82672.1|  aldehyde oxidase [Arabidopsis thaliana]         1501   0.0  
ref|NP_180283.1|  AAO3 (ABSCISIC ALDEHYDE OXIDASE 3) [Arabid...  1499   0.0  
ref|NP_001105309.1|  aldehyde oxidase-2 [Zea mays] >gi|25891...  1499   0.0  
ref|XP_001845789.1|  aldehyde oxidase [Culex pipiens quinque...  1497   0.0  
ref|XP_001657559.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1496   0.0  
ref|XP_793571.2|  PREDICTED: similar to xanthine dehydrogena...  1495   0.0  
emb|CAO67442.1|  unnamed protein product [Vitis vinifera]        1492   0.0  
gb|AAC39509.1|  putative aldehyde oxidase [Arabidopsis thali...  1491   0.0  
gb|ABS32108.1|  aldehyde oxidase 1 [Pisum sativum]               1491   0.0  
gb|EAY77650.1|  hypothetical protein OsI_031609 [Oryza sativ...  1488   0.0  
ref|XP_001657560.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1488   0.0  
ref|XP_001688700.1|  AGAP005637-PA [Anopheles gambiae str. P...  1488   0.0  
ref|XP_001864333.1|  xanthine dehydrogenase/oxidase [Culex p...  1484   0.0  
ref|NP_650477.1|  CG6045 CG6045-PA [Drosophila melanogaster]...  1483   0.0  
gb|EAZ39412.1|  hypothetical protein OsJ_022895 [Oryza sativ...  1483   0.0  
gb|AAO41437.1|  RE51958p [Drosophila melanogaster]               1482   0.0  
gb|EAZ03500.1|  hypothetical protein OsI_024732 [Oryza sativ...  1479   0.0  
gb|ABS32110.1|  aldehyde oxidase 3 [Pisum sativum]               1476   0.0  
gb|AAG22605.1|AF258808_1  aldehyde oxidase [Lycopersicon esc...  1474   0.0  
dbj|BAE93768.1|  aldehyde oxidase [Brassica rapa subsp. peki...  1468   0.0  
ref|XP_315656.4|  AGAP005638-PA [Anopheles gambiae str. PEST...  1464   0.0  
gb|ABS32109.1|  aldehyde oxidase 2 [Pisum sativum]               1460   0.0  
sp|Q6Z351|ALDOL_ORYSJ  Putative aldehyde oxidase-like protei...  1458   0.0  
dbj|BAE93767.1|  aldehyde oxidase [Brassica rapa subsp. peki...  1457   0.0  
ref|XP_001360072.1|  GA19318-PA [Drosophila pseudoobscura] >...  1456   0.0  
dbj|BAE72098.1|  Lactuca sativa aldehyde oxidase 1               1447   0.0  
dbj|BAC79746.1|  putative aldehyde oxidase [Oryza sativa Jap...  1445   0.0  
ref|XP_001688831.1|  AGAP006221-PA [Anopheles gambiae str. P...  1445   0.0  
ref|XP_315654.3|  AGAP005636-PA [Anopheles gambiae str. PEST...  1445   0.0  
ref|XP_001360073.1|  GA14970-PA [Drosophila pseudoobscura] >...  1438   0.0  
ref|XP_001606247.1|  PREDICTED: similar to aldehyde oxidase ...  1438   0.0  
ref|XP_001360071.1|  GA14972-PA [Drosophila pseudoobscura] >...  1433   0.0  
ref|XP_001866985.1|  aldehyde oxidase 2 [Culex pipiens quinq...  1428   0.0  
ref|NP_650478.1|  CG18516 CG18516-PA [Drosophila melanogaste...  1427   0.0  
ref|NP_650475.1|  CG18522 CG18522-PA [Drosophila melanogaste...  1426   0.0  
dbj|BAB23485.1|  unnamed protein product [Mus musculus]          1425   0.0  
ref|XP_688983.2|  PREDICTED: similar to xanthine dehydrogena...  1425   0.0  
ref|NP_732047.1|  CG18519 CG18519-PB, isoform B [Drosophila ...  1411   0.0  
ref|XP_967707.1|  PREDICTED: similar to CG6045-PA [Tribolium...  1404   0.0  
ref|XP_001654493.1|  aldehyde oxidase [Aedes aegypti] >gi|10...  1401   0.0  
ref|NP_001103811.1|  aldehyde oxidase 2 [Bombyx mori] >gi|15...  1391   0.0  
ref|XP_001326092.1|  aldehyde oxidase and xanthine dehydroge...  1390   0.0  
ref|XP_001603962.1|  PREDICTED: similar to aldehyde oxidase ...  1388   0.0  
ref|NP_001103812.1|  aldehyde oxidase 1 [Bombyx mori] >gi|15...  1386   0.0  
gb|AAY24265.1|  unknown [Homo sapiens]                           1386   0.0  
ref|XP_001637029.1|  predicted protein [Nematostella vectens...  1386   0.0  
ref|XP_968525.1|  PREDICTED: similar to CG18522-PA [Triboliu...  1382   0.0  
ref|XP_001584737.1|  hypothetical protein SS1G_14350 [Sclero...  1379   0.0  
ref|XP_001782658.1|  predicted protein [Physcomitrella paten...  1378   0.0  
ref|NP_650476.1|  CG18519 CG18519-PA, isoform A [Drosophila ...  1365   0.0  
pdb|1FIQ|C  Chain C, Crystal Structure Of Xanthine Oxidase F...  1360   0.0  
gb|EAY92133.1|  hypothetical protein OsI_013366 [Oryza sativ...  1354   0.0  
ref|XP_001360074.1|  GA14971-PA [Drosophila pseudoobscura] >...  1344   0.0  
ref|XP_001767396.1|  predicted protein [Physcomitrella paten...  1337   0.0  
gb|EAZ38800.1|  hypothetical protein OsJ_022283 [Oryza sativ...  1312   0.0  
gb|AAB41742.1|  aldehyde oxidase 1 homolog [Lycopersicon esc...  1309   0.0  
ref|XP_001509402.1|  PREDICTED: similar to xanthine dehydrog...  1305   0.0  
ref|XP_001773979.1|  predicted protein [Physcomitrella paten...  1303   0.0  
gb|EAZ03503.1|  hypothetical protein OsI_024735 [Oryza sativ...  1293   0.0  
ref|NP_505377.2|  B0222.9 [Caenorhabditis elegans] >gi|26251...  1292   0.0  
gb|EDL38419.1|  xanthine dehydrogenase, isoform CRA_c [Mus m...  1288   0.0  
gb|EAY92132.1|  hypothetical protein OsI_013365 [Oryza sativ...  1280   0.0  
ref|NP_500531.1|  F15E6.6 [Caenorhabditis elegans] >gi|14574...  1276   0.0  
gb|AAM11042.1|  GH08847p [Drosophila melanogaster]               1255   0.0  
emb|CAO16329.1|  unnamed protein product [Vitis vinifera]        1223   0.0  
ref|XP_001497159.1|  PREDICTED: similar to aldehyde oxidase ...  1216   0.0  
gb|EDL00070.1|  aldehyde oxidase 4 [Mus musculus]                1215   0.0  
gb|EDL99006.1|  rCG22519, isoform CRA_a [Rattus norvegicus]      1209   0.0  
gb|EAW70211.1|  hCG1811467 [Homo sapiens]                        1197   0.0  
gb|AAM11074.1|  GH20168p [Drosophila melanogaster]               1196   0.0  
gb|AAX13175.1|  rosy [Drosophila miranda]                        1191   0.0  
gb|AAX13168.1|  rosy [Drosophila miranda] >gi|60100070|gb|AA...  1190   0.0  
gb|AAX13176.1|  rosy [Drosophila miranda] >gi|60100086|gb|AA...  1189   0.0  
gb|AAX13179.1|  rosy [Drosophila miranda]                        1189   0.0  
gb|AAX13174.1|  rosy [Drosophila miranda]                        1189   0.0  
gb|AAX13171.1|  rosy [Drosophila miranda]                        1189   0.0  
ref|ZP_02009720.1|  aldehyde oxidase and xanthine dehydrogen...  1189   0.0  
gb|AAX13180.1|  rosy [Drosophila pseudoobscura]                  1188   0.0  
gb|AAX13170.1|  rosy [Drosophila miranda] >gi|60100076|gb|AA...  1187   0.0  
gb|AAX13167.1|  rosy [Drosophila affinis]                        1187   0.0  
ref|YP_001899813.1|  xanthine dehydrogenase, molybdopterin b...  1187   0.0  
gb|AAX13173.1|  rosy [Drosophila miranda]                        1186   0.0  
ref|YP_296632.1|  Xanthine dehydrogenase [Ralstonia eutropha...  1185   0.0  
Sequences not found previously or not previously below threshold:

  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF excluding environmental samples
  from WGS projects
    Posted date:  May 23, 2008  5:56 PM
  Number of letters in database: 883,778,997
  Number of sequences in database:  2,617,685
  
  Database: /host/Blast/data/nr_perl/nr.01
    Posted date:  May 23, 2008  5:54 PM
  Number of letters in database: 976,759,346
  Number of sequences in database:  2,761,413
  
  Database: /host/Blast/data/nr_perl/nr.02
    Posted date:  May 23, 2008  5:48 PM
  Number of letters in database: 374,670,760
  Number of sequences in database:  1,165,270
  
  Database: /host/Blast/data/nr_perl/nr.03
    Posted date:  Apr 28, 2009  5:40 PM
  Number of letters in database: 114,943,120
  Number of sequences in database:  354,819
  
Lambda     K      H
   0.315    0.189    0.629 

Lambda     K      H
   0.267   0.0579    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,983,707,576
Number of Sequences: 6899187
Number of extensions: 1791548545
Number of successful extensions: 3526703
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 11839
Number of HSP's successfully gapped in prelim test: 2039
Number of HSP's that attempted gapping in prelim test: 3439439
Number of HSP's gapped (non-prelim): 27975
length of query: 1333
length of database: 2,350,152,223
effective HSP length: 147
effective length of query: 1186
effective length of database: 1,335,971,734
effective search space: 1584462476524
effective search space used: 1584462476524
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 86 (37.2 bits)