BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= ENSG00000163344__[Homo_sapiens]
(192 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
gb|AAQ02411.1| phosphomevalonate kinase [synthetic construct] 381 e-104
ref|NP_006547.1| phosphomevalonate kinase [Homo sapiens] >g... 381 e-104
gb|AAX37126.1| phosphomevalonate kinase [synthetic construct] 381 e-104
gb|AAV38778.1| phosphomevalonate kinase [synthetic construc... 380 e-104
gb|AAV38779.1| phosphomevalonate kinase [Homo sapiens] >gi|... 380 e-104
ref|XP_513842.2| PREDICTED: phosphomevalonate kinase [Pan t... 377 e-103
ref|XP_001114509.1| PREDICTED: phosphomevalonate kinase [Ma... 370 e-101
ref|XP_001497725.1| PREDICTED: similar to phosphomevalonate... 362 7e-99
ref|NP_001039616.1| phosphomevalonate kinase [Bos taurus] >... 351 1e-95
ref|NP_001008353.1| phosphomevalonate kinase [Rattus norveg... 335 1e-90
ref|XP_855082.1| PREDICTED: similar to Phosphomevalonate ki... 335 1e-90
sp|Q9D1G2|PMVK_MOUSE Phosphomevalonate kinase (PMKase) >gi|... 333 5e-90
dbj|BAE40294.1| unnamed protein product [Mus musculus] >gi|... 332 7e-90
ref|NP_081060.1| phosphomevalonate kinase [Mus musculus] >g... 328 9e-89
gb|EDL15190.1| phosphomevalonate kinase, isoform CRA_a [Mus... 324 2e-87
gb|AAC60791.1| phosphomevalonate kinase [Homo sapiens] 319 7e-86
ref|XP_001373420.1| PREDICTED: similar to Phosphomevalonate... 305 1e-81
dbj|BAB28875.1| unnamed protein product [Mus musculus] >gi|... 283 4e-75
gb|EDM00620.1| phosphomevalonate kinase, isoform CRA_a [Rat... 246 7e-64
sp|Q29081|PMVK_PIG Phosphomevalonate kinase (PMKase) 242 1e-62
ref|NP_001077048.1| phosphomevalonate kinase [Danio rerio] ... 225 1e-57
ref|XP_689489.2| PREDICTED: similar to Phosphomevalonate ki... 224 2e-57
gb|AAH28659.1| Pmvk protein [Mus musculus] 207 2e-52
gb|EDM00621.1| phosphomevalonate kinase, isoform CRA_b [Rat... 207 3e-52
ref|NP_001089752.1| hypothetical protein LOC734816 [Xenopus... 205 1e-51
gb|AAC37331.1| phosphomevalonate kinase 197 3e-49
ref|XP_001635081.1| predicted protein [Nematostella vectens... 185 2e-45
dbj|BAF62110.1| phosphomevalonate kinase [Bombyx mori] 181 2e-44
ref|XP_001748282.1| predicted protein [Monosiga brevicollis... 179 9e-44
ref|NP_001040145.1| phosphomevalonate kinase [Bombyx mori] ... 179 1e-43
ref|XP_974268.1| PREDICTED: similar to Phosphomevalonate ki... 178 2e-43
ref|XP_001120920.1| PREDICTED: similar to Phosphomevalonate... 171 2e-41
ref|XP_001604440.1| PREDICTED: similar to phosphomevalonate... 166 1e-39
ref|XP_310779.4| AGAP000338-PA [Anopheles gambiae str. PEST... 164 4e-39
ref|XP_001664006.1| phosphomevalonate kinase, putative [Aed... 155 9e-37
gb|ABF18214.1| phosphomevalonate kinase [Aedes aegypti] 153 5e-36
gb|AAW26333.1| SJCHGC02790 protein [Schistosoma japonicum] 147 4e-34
ref|XP_001673885.1| Hypothetical protein CBG09742 [Caenorha... 145 1e-33
ref|XP_001357257.1| GA10206-PA [Drosophila pseudoobscura] >... 145 1e-33
gb|AAM51057.1| SD12705p [Drosophila melanogaster] 141 2e-32
ref|NP_609992.1| CG10268 CG10268-PA [Drosophila melanogaste... 140 4e-32
ref|XP_001866014.1| phosphomevalonate kinase [Culex pipiens... 140 7e-32
gb|EDM00623.1| phosphomevalonate kinase, isoform CRA_d [Rat... 137 5e-31
ref|NP_872133.1| F32D8.13 [Caenorhabditis elegans] >gi|2831... 137 5e-31
emb|CAF95044.1| unnamed protein product [Tetraodon nigrovir... 129 1e-28
gb|AAP06404.1| similar to GenBank Accession Number AP001507... 93 9e-18
ref|XP_001892529.1| phosphomevalonate kinase [Brugia malayi... 83 1e-14
ref|YP_278526.1| hypothetical protein MS53_0403 [Mycoplasma... 47 9e-04
ref|XP_001801140.1| hypothetical protein SNOG_10882 [Phaeos... 46 0.001
ref|XP_001517271.1| PREDICTED: similar to phosphomevalonate... 44 0.004
ref|XP_001907258.1| unnamed protein product [Podospora anse... 42 0.022
gb|ABA40789.1| SJCHGC02791 protein [Schistosoma japonicum] 40 0.060
ref|XP_001559442.1| hypothetical protein BC1G_02106 [Botryo... 40 0.11
ref|XP_001818778.1| hypothetical protein [Aspergillus oryza... 40 0.12
ref|XP_001211374.1| conserved hypothetical protein [Aspergi... 39 0.25
ref|XP_359731.1| hypothetical protein MGG_05046 [Magnaporth... 39 0.25
ref|XP_001270504.1| phosphoribosyl transferase domain prote... 38 0.39
gb|EDU43013.1| 6-hydroxy-D-nicotine oxidase [Pyrenophora tr... 38 0.43
emb|CAI22034.1| DEAH (Asp-Glu-Ala-His) box polypeptide 35 [... 37 0.68
ref|XP_001224477.1| hypothetical protein CHGG_06821 [Chaeto... 36 1.1
ref|XP_001502677.1| PREDICTED: similar to DEAH (Asp-Glu-Ala... 36 1.5
ref|XP_383779.1| hypothetical protein FG03603.1 [Gibberella... 36 1.6
ref|NP_001102071.1| DEAH (Asp-Glu-Ala-His) box polypeptide ... 35 1.9
ref|YP_995725.1| RNA polymerase, sigma 28 subunit, FliA/Whi... 35 2.2
gb|AAI61396.1| Unknown (protein for IMAGE:7690178) [Xenopus... 35 3.7
ref|ZP_01910857.1| probable short chain dehydrogenase [Ples... 34 4.9
ref|ZP_02994750.1| hypothetical protein CLOSPO_01869 [Clost... 34 5.8
ref|YP_785102.1| 3,4-dihydroxy-2-butanone 4-phosphate synth... 34 6.7
ref|YP_001019272.1| putative recombinase A [Methylibium pet... 34 6.9
ref|YP_001893684.1| conserved hypothetical protein [Burkhol... 33 8.7
ref|ZP_01386618.1| 4Fe-4S ferredoxin, iron-sulfur binding [... 33 9.0
ref|ZP_03990117.1| possible [acyl-carrier-protein] S-malony... 33 9.6
ref|NP_874257.1| guanosine-3',5'-bis(diphosphate) 3'- pyrop... 33 9.7
>gb|AAQ02411.1| phosphomevalonate kinase [synthetic construct]
Length = 193
Score = 381 bits (979), Expect = e-104, Method: Composition-based stats.
Identities = 192/192 (100%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>ref|NP_006547.1| phosphomevalonate kinase [Homo sapiens]
sp|Q15126|PMVK_HUMAN Phosphomevalonate kinase (PMKase)
gb|AAC37593.1| phosphomevalonate kinase
gb|AAH06089.1| Phosphomevalonate kinase [Homo sapiens]
gb|AAH07694.1| Phosphomevalonate kinase [Homo sapiens]
emb|CAG46795.1| PMVK [Homo sapiens]
emb|CAI13237.1| phosphomevalonate kinase [Homo sapiens]
gb|EAW53177.1| phosphomevalonate kinase, isoform CRA_a [Homo sapiens]
gb|EAW53178.1| phosphomevalonate kinase, isoform CRA_a [Homo sapiens]
Length = 192
Score = 381 bits (978), Expect = e-104, Method: Composition-based stats.
Identities = 192/192 (100%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>gb|AAX37126.1| phosphomevalonate kinase [synthetic construct]
Length = 193
Score = 381 bits (978), Expect = e-104, Method: Composition-based stats.
Identities = 192/192 (100%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>gb|AAV38778.1| phosphomevalonate kinase [synthetic construct]
gb|AAX42912.1| phosphomevalonate kinase [synthetic construct]
gb|AAX42913.1| phosphomevalonate kinase [synthetic construct]
gb|AAX42914.1| phosphomevalonate kinase [synthetic construct]
Length = 193
Score = 380 bits (976), Expect = e-104, Method: Composition-based stats.
Identities = 191/192 (99%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAMTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>gb|AAV38779.1| phosphomevalonate kinase [Homo sapiens]
gb|AAX41326.1| phosphomevalonate kinase [synthetic construct]
gb|AAX41327.1| phosphomevalonate kinase [synthetic construct]
gb|AAX41328.1| phosphomevalonate kinase [synthetic construct]
Length = 192
Score = 380 bits (975), Expect = e-104, Method: Composition-based stats.
Identities = 191/192 (99%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAMTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>ref|XP_513842.2| PREDICTED: phosphomevalonate kinase [Pan troglodytes]
Length = 192
Score = 377 bits (968), Expect = e-103, Method: Composition-based stats.
Identities = 189/192 (98%), Positives = 189/192 (98%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVT ALQS LGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTXALQSXLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQ LEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQHLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>ref|XP_001114509.1| PREDICTED: phosphomevalonate kinase [Macaca mulatta]
Length = 192
Score = 370 bits (951), Expect = e-101, Method: Composition-based stats.
Identities = 187/192 (97%), Positives = 188/192 (97%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPL GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLAGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDASTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFG FDWVIENHG EQRLEEQ
Sbjct: 121 AYGAMTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGGFDWVIENHGDEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>ref|XP_001497725.1| PREDICTED: similar to phosphomevalonate kinase [Equus caballus]
Length = 192
Score = 362 bits (929), Expect = 7e-99, Method: Composition-based stats.
Identities = 178/192 (92%), Positives = 186/192 (96%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEA QSRLGADVCA+LRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEAPQSRLGADVCAILRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKEA+R+DMIRWGEEKRQADPGFFCRKIVEG+SQP+WLVSDTRRVSDIQWF+E
Sbjct: 61 RLLDASTYKEAYRRDMIRWGEEKRQADPGFFCRKIVEGVSQPVWLVSDTRRVSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
YGA+TQT+RVVALEQSRQQRGWVFTPGVDDAESECGLDNFG FDWVIENHG EQRLEEQ
Sbjct: 121 TYGAMTQTIRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGGFDWVIENHGDEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFI SRL
Sbjct: 181 LENLIEFIHSRL 192
>ref|NP_001039616.1| phosphomevalonate kinase [Bos taurus]
sp|Q2KIU2|PMVK_BOVIN Phosphomevalonate kinase (PMKase)
gb|AAI12510.1| Phosphomevalonate kinase [Bos taurus]
Length = 192
Score = 351 bits (901), Expect = 1e-95, Method: Composition-based stats.
Identities = 173/192 (90%), Positives = 182/192 (94%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGG P LVLLFSGKRKSGKDFVTEALQSRLGADVCA+LRLSGPLKEQYAQEHGL+FQ
Sbjct: 1 MAPLGGVPGLVLLFSGKRKSGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RL+D STYKEA+R DMIRWGEEKRQADPGFFCRKIVEG+ QP+WLVSDTRRVSDIQWF+E
Sbjct: 61 RLMDASTYKEAYRSDMIRWGEEKRQADPGFFCRKIVEGVCQPVWLVSDTRRVSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVA E+SRQQRGWVFTPGVDDAESECGLDNF FDWVIENHG EQ LEEQ
Sbjct: 121 AYGAVTQTVRVVATEESRQQRGWVFTPGVDDAESECGLDNFRTFDWVIENHGDEQHLEEQ 180
Query: 181 LENLIEFIRSRL 192
LE+LIEFIRSRL
Sbjct: 181 LEHLIEFIRSRL 192
>ref|NP_001008353.1| phosphomevalonate kinase [Rattus norvegicus]
gb|AAH86349.1| Phosphomevalonate kinase [Rattus norvegicus]
gb|EDM00622.1| phosphomevalonate kinase, isoform CRA_c [Rattus norvegicus]
Length = 194
Score = 335 bits (859), Expect = 1e-90, Method: Composition-based stats.
Identities = 164/192 (85%), Positives = 181/192 (94%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE LQSRLG ++CAVLRLSGPLKEQYA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLQSRLGGNICAVLRLSGPLKEQYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
+LLD STYKE +R+DMI WGEEKRQADPGFFCRKIVEG+SQPIWLVSDTRR+SDIQWF+E
Sbjct: 61 KLLDASTYKETYRRDMICWGEEKRQADPGFFCRKIVEGVSQPIWLVSDTRRMSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVA EQSRQQRGWVFT GVDDAESECGLD+FGDFDWVIENHG EQ LE+Q
Sbjct: 121 AYGALTQTVRVVASEQSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LENL+EFI ++L
Sbjct: 181 LENLLEFIHAKL 192
>ref|XP_855082.1| PREDICTED: similar to Phosphomevalonate kinase (PMKase) [Canis
familiaris]
Length = 192
Score = 335 bits (859), Expect = 1e-90, Method: Composition-based stats.
Identities = 168/192 (87%), Positives = 178/192 (92%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAP GGAP LVLL SGKRKSGKDFV EAL+SRLGADVCAVLRLSGPLKEQYA+EH L+FQ
Sbjct: 1 MAPRGGAPCLVLLVSGKRKSGKDFVAEALRSRLGADVCAVLRLSGPLKEQYAKEHDLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD S YKEAFR+DMIRWGEEKRQADPGFFCRK+VEG+ QP+WLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDASAYKEAFRRDMIRWGEEKRQADPGFFCRKVVEGVFQPVWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVA EQSRQQRGWVFT GVDDAESECGLDNFG FDWVIENHG EQRLEEQ
Sbjct: 121 AYGALTQTVRVVASEQSRQQRGWVFTTGVDDAESECGLDNFGAFDWVIENHGDEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LE L+ F+RSRL
Sbjct: 181 LEKLVVFVRSRL 192
>sp|Q9D1G2|PMVK_MOUSE Phosphomevalonate kinase (PMKase)
gb|EDL15192.1| phosphomevalonate kinase, isoform CRA_c [Mus musculus]
Length = 192
Score = 333 bits (853), Expect = 5e-90, Method: Composition-based stats.
Identities = 160/192 (83%), Positives = 180/192 (93%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE +R+DMI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+E
Sbjct: 61 RLLDASTYKETYRRDMICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAV QTVRVVA EQSRQQRGWVFTPGVDDAESECGLDNFG+FDWVIENHG EQ LE+Q
Sbjct: 121 AYGAVIQTVRVVASEQSRQQRGWVFTPGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LE+L+ FI+++L
Sbjct: 181 LEHLLGFIQAKL 192
>dbj|BAE40294.1| unnamed protein product [Mus musculus]
dbj|BAE29599.1| unnamed protein product [Mus musculus]
Length = 192
Score = 332 bits (852), Expect = 7e-90, Method: Composition-based stats.
Identities = 160/192 (83%), Positives = 179/192 (93%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE +R DMI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+E
Sbjct: 61 RLLDASTYKETYRGDMICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAV QTVRVVA EQSRQQRGWVFTPGVDDAESECGLDNFG+FDWVIENHG EQ LE+Q
Sbjct: 121 AYGAVIQTVRVVASEQSRQQRGWVFTPGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LE+L+ FI+++L
Sbjct: 181 LEHLLGFIQAKL 192
>ref|NP_081060.1| phosphomevalonate kinase [Mus musculus]
dbj|BAB22886.1| unnamed protein product [Mus musculus]
Length = 192
Score = 328 bits (842), Expect = 9e-89, Method: Composition-based stats.
Identities = 159/192 (82%), Positives = 179/192 (93%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE +R+DMI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+E
Sbjct: 61 RLLDASTYKETYRRDMICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAV QTVRVVA EQSRQQRGWVFT GVDDAESECGLDNFG+FDWVIENHG EQ LE+Q
Sbjct: 121 AYGAVIQTVRVVASEQSRQQRGWVFTLGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LE+L+ FI+++L
Sbjct: 181 LEHLLGFIQAKL 192
>gb|EDL15190.1| phosphomevalonate kinase, isoform CRA_a [Mus musculus]
Length = 206
Score = 324 bits (831), Expect = 2e-87, Method: Composition-based stats.
Identities = 161/206 (78%), Positives = 180/206 (87%), Gaps = 14/206 (6%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYA-------- 52
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREGWWDCV 60
Query: 53 ------QEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLV 106
QEHGL+FQRLLD STYKE +R+DMI WGE+KRQADPGFFCRKIVEG+SQPIWLV
Sbjct: 61 IDGLALQEHGLDFQRLLDASTYKETYRRDMICWGEQKRQADPGFFCRKIVEGVSQPIWLV 120
Query: 107 SDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDW 166
SDTRR SDIQWF+EAYGAV QTVRVVA EQSRQQRGWVFTPGVDDAESECGLDNFG+FDW
Sbjct: 121 SDTRRTSDIQWFQEAYGAVIQTVRVVASEQSRQQRGWVFTPGVDDAESECGLDNFGNFDW 180
Query: 167 VIENHGVEQRLEEQLENLIEFIRSRL 192
VIENHG EQ LE+QLE+L+ FI+++L
Sbjct: 181 VIENHGDEQCLEDQLEHLLGFIQAKL 206
>gb|AAC60791.1| phosphomevalonate kinase [Homo sapiens]
Length = 160
Score = 319 bits (817), Expect = 7e-86, Method: Composition-based stats.
Identities = 160/160 (100%), Positives = 160/160 (100%)
Query: 33 LGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFC 92
LGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFC
Sbjct: 1 LGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFC 60
Query: 93 RKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDA 152
RKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDA
Sbjct: 61 RKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDA 120
Query: 153 ESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
ESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL
Sbjct: 121 ESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 160
>ref|XP_001373420.1| PREDICTED: similar to Phosphomevalonate kinase [Monodelphis
domestica]
Length = 204
Score = 305 bits (780), Expect = 1e-81, Method: Composition-based stats.
Identities = 149/192 (77%), Positives = 172/192 (89%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAP +PRLVLLFSGKRKSGKDFVT+ L+SRLG DVCAVLRLSGPLKEQYA+EHGL+FQ
Sbjct: 1 MAPRVDSPRLVLLFSGKRKSGKDFVTDELRSRLGTDVCAVLRLSGPLKEQYAKEHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD S+YKEAFR+DMIRWGEEKR+ADPGFFCRKIVEG+ QP+WLVSDTRR SDI WF+
Sbjct: 61 RLLDASSYKEAFRQDMIRWGEEKREADPGFFCRKIVEGVPQPVWLVSDTRRESDIHWFQA 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
++G VTQ VRVVA E+SR+QRGWVFT GVDDAESECGLD+F FDWVIENHG +++LE+Q
Sbjct: 121 SFGDVTQLVRVVASEESRRQRGWVFTAGVDDAESECGLDHFEAFDWVIENHGEDRKLEQQ 180
Query: 181 LENLIEFIRSRL 192
L L++FI S+L
Sbjct: 181 LGKLVDFIHSKL 192
>dbj|BAB28875.1| unnamed protein product [Mus musculus]
gb|EDL15191.1| phosphomevalonate kinase, isoform CRA_b [Mus musculus]
Length = 171
Score = 283 bits (725), Expect = 4e-75, Method: Composition-based stats.
Identities = 133/162 (82%), Positives = 152/162 (93%)
Query: 31 SRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGF 90
+RLG ++CA+LRLSGPLKE+YA+EHGL+FQRLLD STYKE +R+DMI WGE+KRQADPGF
Sbjct: 10 ARLGGNICALLRLSGPLKEEYAREHGLDFQRLLDASTYKETYRRDMICWGEQKRQADPGF 69
Query: 91 FCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVD 150
FCRKIVEG+SQPIWLVSDTRR SDIQWF+EAYGAV QTVRVVA EQSRQQRGWVFTPGVD
Sbjct: 70 FCRKIVEGVSQPIWLVSDTRRTSDIQWFQEAYGAVIQTVRVVASEQSRQQRGWVFTPGVD 129
Query: 151 DAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
DAESECGLDNFG+FDWVIENHG EQ LE+QLE+L+ FI+++L
Sbjct: 130 DAESECGLDNFGNFDWVIENHGDEQCLEDQLEHLLGFIQAKL 171
>gb|EDM00620.1| phosphomevalonate kinase, isoform CRA_a [Rattus norvegicus]
Length = 147
Score = 246 bits (627), Expect = 7e-64, Method: Composition-based stats.
Identities = 119/140 (85%), Positives = 132/140 (94%)
Query: 53 QEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRV 112
QEHGL+FQ+LLD STYKE +R+DMI WGEEKRQADPGFFCRKIVEG+SQPIWLVSDTRR+
Sbjct: 6 QEHGLDFQKLLDASTYKETYRRDMICWGEEKRQADPGFFCRKIVEGVSQPIWLVSDTRRM 65
Query: 113 SDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHG 172
SDIQWF+EAYGA+TQTVRVVA EQSRQQRGWVFT GVDDAESECGLD+FGDFDWVIENHG
Sbjct: 66 SDIQWFQEAYGALTQTVRVVASEQSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENHG 125
Query: 173 VEQRLEEQLENLIEFIRSRL 192
EQ LE+QLENL+EFI ++L
Sbjct: 126 DEQCLEDQLENLLEFIHAKL 145
>sp|Q29081|PMVK_PIG Phosphomevalonate kinase (PMKase)
Length = 130
Score = 242 bits (617), Expect = 1e-62, Method: Composition-based stats.
Identities = 116/129 (89%), Positives = 124/129 (96%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG PRLVLLFSGKRK GKDFVTEALQSRLGADVCA+LRLSGPLKEQYAQEHGL+FQ
Sbjct: 1 MAPLGSVPRLVLLFSGKRKDGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE++RKDMIRWG+EKRQADPGFFCRKIVEG+SQPIWLVSDTRR+SDIQWF+E
Sbjct: 61 RLLDASTYKESYRKDMIRWGQEKRQADPGFFCRKIVEGVSQPIWLVSDTRRLSDIQWFQE 120
Query: 121 AYGAVTQTV 129
YGAVTQTV
Sbjct: 121 TYGAVTQTV 129
>ref|NP_001077048.1| phosphomevalonate kinase [Danio rerio]
ref|XP_689711.2| PREDICTED: similar to Phosphomevalonate kinase [Danio rerio]
gb|AAI35046.1| Zgc:162701 protein [Danio rerio]
Length = 199
Score = 225 bits (574), Expect = 1e-57, Method: Composition-based stats.
Identities = 102/185 (55%), Positives = 139/185 (75%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
P ++LLFSGKRKSGKD+VT+ +Q RL A++C +LRLS PLKEQYA++H L+++ L+ +
Sbjct: 6 PSIILLFSGKRKSGKDYVTDLIQKRLTAEICCILRLSAPLKEQYAKDHNLDYEELMGSGQ 65
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQ 127
YKE++R DMI WGE KRQ D GFFCR ++ +QP+W++SD RR+SD+QWFREA+
Sbjct: 66 YKESYRADMIHWGEMKRQEDSGFFCRLAIKHATQPVWIISDCRRMSDVQWFREAFPNKCV 125
Query: 128 TVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEF 187
VRV A EQ+R +RGW FT G+DDAESECGLD FD +I N G + LE+ L+ L+
Sbjct: 126 CVRVEASEQTRSERGWRFTSGIDDAESECGLDEGVKFDRIIRNDGSDDILEKHLDELLSS 185
Query: 188 IRSRL 192
+RS++
Sbjct: 186 VRSQV 190
>ref|XP_689489.2| PREDICTED: similar to Phosphomevalonate kinase [Danio rerio]
Length = 199
Score = 224 bits (571), Expect = 2e-57, Method: Composition-based stats.
Identities = 102/185 (55%), Positives = 139/185 (75%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
P ++LLFSGKRKSGKD+VT+ +Q RL A++C +LRLS PLKEQYA++H L+++ L+ +
Sbjct: 6 PSIILLFSGKRKSGKDYVTDLIQKRLTAEMCCILRLSAPLKEQYAKDHNLDYEELMGSGQ 65
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQ 127
YKE++R DMI WGE KRQ D GFFCR ++ +QP+W++SD RR+SD+QWFREA+
Sbjct: 66 YKESYRADMIHWGEMKRQEDSGFFCRLAIKHATQPVWIISDCRRMSDVQWFREAFPNKCV 125
Query: 128 TVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEF 187
VRV A EQ+R +RGW FT G+DDAESECGLD FD +I N G + LE+ L+ L+
Sbjct: 126 CVRVEASEQTRSERGWRFTSGIDDAESECGLDEGVKFDRIIRNDGSDDILEKHLDELLSS 185
Query: 188 IRSRL 192
+RS++
Sbjct: 186 VRSQV 190
>gb|AAH28659.1| Pmvk protein [Mus musculus]
Length = 117
Score = 207 bits (528), Expect = 2e-52, Method: Composition-based stats.
Identities = 100/117 (85%), Positives = 110/117 (94%)
Query: 76 MIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALE 135
MI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+EAYGAV QTVRVVA E
Sbjct: 1 MICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQEAYGAVIQTVRVVASE 60
Query: 136 QSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
QSRQQRGWVFTPGVDDAESECGLDNFG+FDWVIENHG EQ LE+QLE+L+ FI+++L
Sbjct: 61 QSRQQRGWVFTPGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQLEHLLGFIQAKL 117
>gb|EDM00621.1| phosphomevalonate kinase, isoform CRA_b [Rattus norvegicus]
Length = 119
Score = 207 bits (527), Expect = 3e-52, Method: Composition-based stats.
Identities = 102/117 (87%), Positives = 111/117 (94%)
Query: 76 MIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALE 135
MI WGEEKRQADPGFFCRKIVEG+SQPIWLVSDTRR+SDIQWF+EAYGA+TQTVRVVA E
Sbjct: 1 MICWGEEKRQADPGFFCRKIVEGVSQPIWLVSDTRRMSDIQWFQEAYGALTQTVRVVASE 60
Query: 136 QSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
QSRQQRGWVFT GVDDAESECGLD+FGDFDWVIENHG EQ LE+QLENL+EFI ++L
Sbjct: 61 QSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENHGDEQCLEDQLENLLEFIHAKL 117
>ref|NP_001089752.1| hypothetical protein LOC734816 [Xenopus laevis]
gb|AAI06478.1| MGC131201 protein [Xenopus laevis]
Length = 145
Score = 205 bits (522), Expect = 1e-51, Method: Composition-based stats.
Identities = 99/143 (69%), Positives = 117/143 (81%)
Query: 6 GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDT 65
G PRLVLLFSGKRKSGKD VT +LQ R +D C+VLRLSGPLKEQ+A E GL+++RLL
Sbjct: 2 GEPRLVLLFSGKRKSGKDHVTNSLQLRFSSDTCSVLRLSGPLKEQFALERGLDYERLLGA 61
Query: 66 STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAV 125
+ YKE FR DMIRWGEEKR+ DPGFFCR IV+ +SQP+W++SD RR SDI WFR YGAV
Sbjct: 62 TGYKEEFRADMIRWGEEKRRRDPGFFCRIIVQRVSQPVWIISDARRKSDIDWFRSEYGAV 121
Query: 126 TQTVRVVALEQSRQQRGWVFTPG 148
QTVRV A E++R+ RGWV+TPG
Sbjct: 122 LQTVRVEASEETREARGWVYTPG 144
>gb|AAC37331.1| phosphomevalonate kinase
Length = 106
Score = 197 bits (501), Expect = 3e-49, Method: Composition-based stats.
Identities = 95/105 (90%), Positives = 103/105 (98%)
Query: 16 GKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKD 75
GKRK GKDFVTEALQSRLGADVCA+LRLSGPLKEQYAQEHGL+FQRLLD STYKE++RKD
Sbjct: 1 GKRKDGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQRLLDASTYKESYRKD 60
Query: 76 MIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
MIRWG+EKRQADPGFFCRKIVEG+SQPIWLVSDTRR+SDIQWF+E
Sbjct: 61 MIRWGQEKRQADPGFFCRKIVEGVSQPIWLVSDTRRLSDIQWFQE 105
>ref|XP_001635081.1| predicted protein [Nematostella vectensis]
gb|EDO43018.1| predicted protein [Nematostella vectensis]
Length = 192
Score = 185 bits (469), Expect = 2e-45, Method: Composition-based stats.
Identities = 95/188 (50%), Positives = 128/188 (68%), Gaps = 9/188 (4%)
Query: 4 LGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLL 63
+ P V + SGKRKSGKD+V E L+ LG C +LRLSGPLK +YA+ H L++Q+LL
Sbjct: 1 MAAKPFAVCILSGKRKSGKDYVAERLKILLGKSNCEILRLSGPLKREYARIHKLDYQKLL 60
Query: 64 DTSTYKEAFRKDMIRWGEEKRQADPGFFCR-------KIVEGISQPIWLVSDTRRVSDIQ 116
D+S YKE +RKDMI+WGEEKR A+P +FC + + ++ WLVSD RR++D+Q
Sbjct: 61 DSSDYKEKYRKDMIKWGEEKRNAEPYYFCELAAKMAYRDAQSETKLYWLVSDARRITDLQ 120
Query: 117 WFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQR 176
+F++ Y V VRV A + R +RGW+FT GVDDAESECGLD+ FD I N+G ++
Sbjct: 121 FFQQHYPRVVH-VRVTASDDVRMRRGWMFTNGVDDAESECGLDDV-IFDVAIINNGDNEQ 178
Query: 177 LEEQLENL 184
LE L +L
Sbjct: 179 LENSLASL 186
>dbj|BAF62110.1| phosphomevalonate kinase [Bombyx mori]
Length = 186
Score = 181 bits (459), Expect = 2e-44, Method: Composition-based stats.
Identities = 85/183 (46%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Query: 7 APRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
+P+++LLFSGKRKSGKDF+T+ L+ L AD C ++++S P+K +A+E LN LL
Sbjct: 2 SPKIILLFSGKRKSGKDFLTDHLRHIL-ADKCEIIKISQPIKTHWAKEKNLNLNELLSEG 60
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGIS-QPIWLVSDTRRVSDIQWFREAYGAV 125
YKE +R +MI+W EE R D G FC+ E + +P+W+VSD RR +DI+WF+E YG +
Sbjct: 61 EYKEQYRLEMIKWSEEMRNKDYGCFCKAACENAAIKPVWIVSDIRRKTDIRWFKETYGDI 120
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLI 185
+TVR+ A +++R++RG+ F GVDDA SEC LD++ D+D V+ N LEEQL++++
Sbjct: 121 IRTVRITADDRTRKERGFQFQVGVDDATSECDLDDYNDWDVVVNNGEGRDSLEEQLDSIL 180
Query: 186 EFI 188
+ +
Sbjct: 181 KLV 183
>ref|XP_001748282.1| predicted protein [Monosiga brevicollis MX1]
gb|EDQ87043.1| predicted protein [Monosiga brevicollis MX1]
Length = 234
Score = 179 bits (454), Expect = 9e-44, Method: Composition-based stats.
Identities = 100/186 (53%), Positives = 121/186 (65%), Gaps = 4/186 (2%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLG-ADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
P+LVLLFSGKRKSGKD++ + L R A V A +RLS PLK QYA +HGL++Q LL S
Sbjct: 51 PKLVLLFSGKRKSGKDYLADQLAQRPDLAPVLAQVRLSAPLKRQYALDHGLDYQELLSAS 110
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVT 126
TYKE R+ MI WGE+KR+ADPGFF R + PIWLV D RR +D+ +F+ Y V
Sbjct: 111 TYKEQHRQAMIVWGEQKRRADPGFFARLATHDLQAPIWLVVDCRRQTDLTYFQTRYPCV- 169
Query: 127 QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIE 186
TVRV A +R QRG+ FT GVDDAESECGLD D VI+N G Q L+ L+
Sbjct: 170 -TVRVQASVATRAQRGYTFTTGVDDAESECGLDAV-QHDIVIDNDGDGQATAAALDQLLA 227
Query: 187 FIRSRL 192
I L
Sbjct: 228 QIHQSL 233
>ref|NP_001040145.1| phosphomevalonate kinase [Bombyx mori]
gb|ABD36154.1| phosphomevalonate kinase [Bombyx mori]
Length = 186
Score = 179 bits (453), Expect = 1e-43, Method: Composition-based stats.
Identities = 84/183 (45%), Positives = 127/183 (69%), Gaps = 2/183 (1%)
Query: 7 APRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
+P+++LLFSGKRKSGKDF+T+ L+ L AD C ++++S P+K +A+E LN LL
Sbjct: 2 SPKIILLFSGKRKSGKDFLTDHLRHIL-ADKCEIIKISQPIKTHWAKEKNLNLNELLSEG 60
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGIS-QPIWLVSDTRRVSDIQWFREAYGAV 125
YKE +R +MI+W EE R D G FC+ E + +P+W+VSD RR +DI+WF+E YG +
Sbjct: 61 EYKEQYRLEMIKWSEEMRNKDYGCFCKAACENAAIKPVWIVSDIRRKTDIRWFKETYGDI 120
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLI 185
+TVR+ A +++R++RG+ F GVDDA SEC LD++ D D V+ N LEE L++++
Sbjct: 121 IRTVRITADDRTRKERGFQFQVGVDDATSECDLDDYNDGDVVVNNGEGRDSLEEPLDSIL 180
Query: 186 EFI 188
+ +
Sbjct: 181 KLV 183
>ref|XP_974268.1| PREDICTED: similar to Phosphomevalonate kinase (PMKase) [Tribolium
castaneum]
Length = 189
Score = 178 bits (452), Expect = 2e-43, Method: Composition-based stats.
Identities = 88/186 (47%), Positives = 125/186 (67%), Gaps = 6/186 (3%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGL---NFQRLLD 64
PRL+LLFSGKRKSGKD++ EAL++ LG + C ++R+SGPLK YA+ H L + ++
Sbjct: 4 PRLILLFSGKRKSGKDYICEALKANLGDNNCTIIRISGPLKRLYAESHDLTTGDVNEMMT 63
Query: 65 TSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGIS-QPIWLVSDTRRVSDIQWFREAY- 122
KE FR +MI+W +E R D GFFC+ + +P W+VSD RR +DI WF+ Y
Sbjct: 64 DGPLKEKFRAEMIQWSDEIRGRDFGFFCKAATDLADLKPFWIVSDIRRKTDIHWFKNTYK 123
Query: 123 GAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLE 182
+ + +R+ A E +RQ+RGWVFT GVDD SEC LD+F D+D +I+N+ E+ L E L
Sbjct: 124 DKIIKLIRIQADEVTRQKRGWVFTEGVDDVTSECDLDDFSDWDLIIKNNNAEE-LGEGLG 182
Query: 183 NLIEFI 188
L++F+
Sbjct: 183 KLMQFL 188
>ref|XP_001120920.1| PREDICTED: similar to Phosphomevalonate kinase (PMKase) [Apis
mellifera]
Length = 202
Score = 171 bits (434), Expect = 2e-41, Method: Composition-based stats.
Identities = 76/184 (41%), Positives = 118/184 (64%), Gaps = 5/184 (2%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
P+++LLFSGKRK GKD++T L R+G+D ++++S P+K +A+ HGLN +L+
Sbjct: 20 PKIILLFSGKRKCGKDYITNILYERIGSDNSVIIKISAPIKSHWAKSHGLNIDQLMGDGK 79
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCR---KIVEGISQPIWLVSDTRRVSDIQWFREAYGA 124
YKE +R +M +WGE R D G+FCR I + IW+VSD RR +DIQWF E +
Sbjct: 80 YKENYRLEMAKWGENIRNTDQGYFCRAALDIYNAYDKSIWIVSDIRRKTDIQWFTENFKD 139
Query: 125 VTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENL 184
+ +T+R+ + + R +RGW F G+DDAE+EC LD+ +D + N+ + +E L+ +
Sbjct: 140 ICKTIRIESDDSIRIERGWTFVTGIDDAETECDLDDVNTWDLKVTNN--TKSIECILQQI 197
Query: 185 IEFI 188
+E I
Sbjct: 198 LELI 201
>ref|XP_001604440.1| PREDICTED: similar to phosphomevalonate kinase [Nasonia
vitripennis]
Length = 204
Score = 166 bits (419), Expect = 1e-39, Method: Composition-based stats.
Identities = 76/184 (41%), Positives = 122/184 (66%), Gaps = 5/184 (2%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
P +L+FSGKRKSGKDF+T+ L +RLG + +++LSGP+K +A+ L+ ++L
Sbjct: 22 PEKILIFSGKRKSGKDFITDELFARLGKEKSVIIKLSGPIKSHWAKIKNLDAKQLFGDGE 81
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIV---EGISQPIWLVSDTRRVSDIQWFREAYGA 124
YKEA+R++M +WGE+ R D G+FCR + +PIW++SD RR +D++WF+E Y
Sbjct: 82 YKEAYRREMTKWGEDTRNKDYGYFCRAAILMYNANDKPIWIISDARRKTDLKWFKEHYAD 141
Query: 125 VTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENL 184
+T+R+ + E+ R+ RGW F G+DD+E+EC LD+ +D I N+G + +E L +
Sbjct: 142 KCKTIRISSSEEVRKNRGWKFCRGIDDSETECDLDDVTYWDLEINNNG--EDIELILHEI 199
Query: 185 IEFI 188
I+ +
Sbjct: 200 IDIL 203
>ref|XP_310779.4| AGAP000338-PA [Anopheles gambiae str. PEST]
gb|EAA06245.5| AGAP000338-PA [Anopheles gambiae str. PEST]
Length = 192
Score = 164 bits (414), Expect = 4e-39, Method: Composition-based stats.
Identities = 86/185 (46%), Positives = 118/185 (63%), Gaps = 3/185 (1%)
Query: 6 GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDT 65
G PR++LL SGKRK GKDF+ +AL RLG D ++R+S P+K +A+ GL+ LL
Sbjct: 7 GVPRVLLLLSGKRKCGKDFLADALLQRLGTDRAQIVRISEPIKRHWAEAMGLDLAALLGD 66
Query: 66 STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAV 125
YKE +R+ MI W + +RQ D G FCR I +PI +VSD RR +D+++FREAYG
Sbjct: 67 GAYKERYRRQMIEWSDGRRQEDYGVFCRAACATIDRPICIVSDVRRQTDVRYFREAYGPE 126
Query: 126 T--QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLEN 183
T +TVR+ A EQ R RGW F GVDD +SEC LD + +D V+ N + + E L+
Sbjct: 127 TRLRTVRIEASEQVRHGRGWQFQAGVDDVQSECDLDGYAGWDLVLTNERPDG-VGELLDR 185
Query: 184 LIEFI 188
L++ I
Sbjct: 186 LVQLI 190
>ref|XP_001664006.1| phosphomevalonate kinase, putative [Aedes aegypti]
gb|EAT33914.1| phosphomevalonate kinase, putative [Aedes aegypti]
Length = 187
Score = 155 bits (393), Expect = 9e-37, Method: Composition-based stats.
Identities = 81/163 (49%), Positives = 115/163 (70%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
PR+VLLFSGKRK GKDF+TE L RL D ++R+S P+K +A++ GL+ LL
Sbjct: 7 PRVVLLFSGKRKCGKDFLTERLLQRLTTDKAQIIRISEPIKRSWAEKLGLDLGELLGDGP 66
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQ 127
YKE +RK+MI W ++KR D GFFCR+ +++ I +VSD RR +D+++FRE YG +
Sbjct: 67 YKERYRKEMIEWSDQKRAEDFGFFCRQACLALAKEICVVSDIRRKTDVRFFREQYGQRIK 126
Query: 128 TVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIEN 170
TVR+VA E +R +RGWVF GVDD +SEC LD+ ++D +++N
Sbjct: 127 TVRIVASEATRVERGWVFQEGVDDVQSECDLDDVTEWDLLVQN 169
>gb|ABF18214.1| phosphomevalonate kinase [Aedes aegypti]
Length = 187
Score = 153 bits (387), Expect = 5e-36, Method: Composition-based stats.
Identities = 80/163 (49%), Positives = 114/163 (69%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
PR+VLLF GKRK GKDF+TE L RL D ++R+S P+K +A++ GL+ LL
Sbjct: 7 PRVVLLFFGKRKCGKDFLTERLLQRLTTDKAQIIRISEPIKRSWAEKLGLDLGELLGDGP 66
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQ 127
YKE +RK+MI W ++KR D GFFCR+ +++ I +VSD RR +D+++FRE YG +
Sbjct: 67 YKERYRKEMIEWSDQKRAEDFGFFCRQACLALAKEICVVSDIRRKTDVRFFREQYGQRIK 126
Query: 128 TVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIEN 170
TVR+VA E +R +RGWVF GVDD +SEC LD+ ++D +++N
Sbjct: 127 TVRIVASEATRVERGWVFQEGVDDVQSECDLDDVTEWDLLVQN 169
>gb|AAW26333.1| SJCHGC02790 protein [Schistosoma japonicum]
Length = 202
Score = 147 bits (371), Expect = 4e-34, Method: Composition-based stats.
Identities = 76/193 (39%), Positives = 121/193 (62%), Gaps = 10/193 (5%)
Query: 10 LVLLFSGKRKSGKDFVTEALQSRLGADVCA--VLRLSGPLKEQYAQEHGLNFQRLLDTST 67
+ ++FSGKRKSGKD+ L + L ++ + V+R+S P+K +A+ +GLN LL ++
Sbjct: 7 ICVVFSGKRKSGKDYTVNHLTNLLQSNHLSYLVVRISEPIKSYFAEHYGLNLSELLSSNE 66
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIV------EGISQP-IWLVSDTRRVSDIQWFRE 120
YKE +RK MI W E++ + DP F RK + GISQP + ++SD RRV+DI++ +
Sbjct: 67 YKENYRKQMISWMEQEIKQDPYVFIRKSLLESTRRHGISQPAVIIISDARRVNDIEYLIK 126
Query: 121 AYG-AVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEE 179
+G + VR+VA + R +RGW + GVD+A SECGLD F ++D+++ N+G + E
Sbjct: 127 TFGRSKCLLVRIVAPIEIRTERGWTYVNGVDNAASECGLDEFTNWDYIVSNNGDKSVFEN 186
Query: 180 QLENLIEFIRSRL 192
L ++ I+ L
Sbjct: 187 HLHVIVAHIKRML 199
>ref|XP_001673885.1| Hypothetical protein CBG09742 [Caenorhabditis briggsae AF16]
Length = 188
Score = 145 bits (367), Expect = 1e-33, Method: Composition-based stats.
Identities = 81/166 (48%), Positives = 106/166 (63%), Gaps = 8/166 (4%)
Query: 9 RLVLLFSGKRKSGKDFVTEALQ---SRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDT 65
+ V+ SGKRKSGKD+ T L ++ V AV +S LKE+YA+ H LNF LL
Sbjct: 3 KFVIAISGKRKSGKDYCTNKLIKAFEKIQLSVSAV-GISHSLKEEYAKIHNLNFAELLTD 61
Query: 66 STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQP-IWLVSDTRRVSDIQWFREAYGA 124
YKE FRKDMIRWGE+ R P FCR + + I +VSD RR++D+++F Y
Sbjct: 62 GPYKEQFRKDMIRWGEDVRNKIPSVFCRAALLSVDDSDIVIVSDCRRITDLEFFVSNYK- 120
Query: 125 VTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIEN 170
T TVRV +E+ RQQRG+ F G+DDAESECGLD++ FD V++N
Sbjct: 121 -TLTVRVETIEEHRQQRGFRFVKGIDDAESECGLDDY-KFDVVLKN 164
>ref|XP_001357257.1| GA10206-PA [Drosophila pseudoobscura]
gb|EAL34326.1| GA10206-PA [Drosophila pseudoobscura]
Length = 185
Score = 145 bits (366), Expect = 1e-33, Method: Composition-based stats.
Identities = 77/182 (42%), Positives = 119/182 (65%), Gaps = 6/182 (3%)
Query: 11 VLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKE 70
++L SGKRK GKD+++E LQ RL + ++R+S P+K ++A++ L+ LL YKE
Sbjct: 4 IVLISGKRKCGKDYISERLQKRL-TNRAIIVRISEPIKSEWARKLQLDLSALLSDGPYKE 62
Query: 71 AFRKDMIRWGEEKRQADPGFFCRKIVE--GISQPIW-LVSDTRRVSDIQWFREAYGA-VT 126
+R+DMI W +E R D G+FCR +E + Q + +VSD RR +DI+WFRE YG +
Sbjct: 63 QYRRDMIVWSDEVRSKDYGYFCRAAMEEAPLDQIAYVIVSDVRRKNDIKWFRETYGQNMV 122
Query: 127 QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGV-EQRLEEQLENLI 185
+TVR+ + ++RQ RGW FT G+DD SEC LD++ FD+V+ N +Q +QL +++
Sbjct: 123 RTVRLTSRPETRQARGWTFTKGIDDVPSECDLDDYDSFDFVVPNEDENDQGFIDQLLDML 182
Query: 186 EF 187
+
Sbjct: 183 QL 184
>gb|AAM51057.1| SD12705p [Drosophila melanogaster]
Length = 189
Score = 141 bits (355), Expect = 2e-32, Method: Composition-based stats.
Identities = 82/188 (43%), Positives = 116/188 (61%), Gaps = 13/188 (6%)
Query: 11 VLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKE 70
++L SGKRK GKD+++E LQ RLG+ C ++R+S P+K ++A + L+ LL YKE
Sbjct: 4 IVLISGKRKCGKDYISERLQRRLGSRSC-IVRISEPIKSEWAHKLQLDLDALLGDGPYKE 62
Query: 71 AFRKDMIRWGEEKRQADPGFFCR-KIVEGISQ---PIWLVSDTRRVSDIQWFREAYGAV- 125
+R+DMI W +E R D G+FCR + E +S+ P LVSD RR +DI+WFRE YG
Sbjct: 63 KYRRDMIVWSDEVRAQDYGYFCRVAMEEALSRQQTPYILVSDVRRKNDIRWFRETYGPER 122
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGD-FDWVIENHGVEQRLEEQLENL 184
T+R+ + ++R RGW FT G+DD SEC LD+ D FD V+ N EE +
Sbjct: 123 VITLRLTSRPETRSARGWTFTAGIDDVPSECDLDDLADGFDVVLAND------EELDQEA 176
Query: 185 IEFIRSRL 192
I+ + RL
Sbjct: 177 IDILLDRL 184
>ref|NP_609992.1| CG10268 CG10268-PA [Drosophila melanogaster]
sp|Q9VIT2|PMVK_DROME Probable phosphomevalonate kinase (PMKase)
gb|AAF53833.1| CG10268-PA [Drosophila melanogaster]
Length = 189
Score = 140 bits (354), Expect = 4e-32, Method: Composition-based stats.
Identities = 77/166 (46%), Positives = 109/166 (65%), Gaps = 7/166 (4%)
Query: 11 VLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKE 70
++L SGKRK GKD+++E LQ RLG+ C ++R+S P+K ++A++ L+ LL YKE
Sbjct: 4 IVLISGKRKCGKDYISERLQRRLGSRSC-IVRISEPIKSEWARKLQLDLDALLGDGPYKE 62
Query: 71 AFRKDMIRWGEEKRQADPGFFCR-KIVEGISQ---PIWLVSDTRRVSDIQWFREAYGAV- 125
+R+DMI W +E R D G+FCR + E +S+ P LVSD RR +DI+WFRE YG
Sbjct: 63 KYRRDMIVWSDEVRAQDYGYFCRVAMEEALSRQQTPYILVSDVRRKNDIRWFRETYGPER 122
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGD-FDWVIEN 170
T+R+ + ++R RGW FT G+DD SEC LD+ D FD V+ N
Sbjct: 123 VITLRLTSRPETRSARGWTFTAGIDDVPSECDLDDLADGFDVVLAN 168
>ref|XP_001866014.1| phosphomevalonate kinase [Culex pipiens quinquefasciatus]
gb|EDS42634.1| phosphomevalonate kinase [Culex pipiens quinquefasciatus]
Length = 186
Score = 140 bits (352), Expect = 7e-32, Method: Composition-based stats.
Identities = 77/168 (45%), Positives = 113/168 (67%), Gaps = 3/168 (1%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
PR+VLLFSGKRK GKD++TE L RL ++R+S P+K +A + GL+ LL
Sbjct: 4 PRIVLLFSGKRKCGKDYLTERLLQRLTPARAQIVRISEPIKRCWADKLGLDLGELLGDGP 63
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIV-EGI--SQPIWLVSDTRRVSDIQWFREAYGA 124
YKE +R++MI W + +R D GFFCR EG+ ++ + +VSD RR +D+++FRE +G
Sbjct: 64 YKERYRREMIEWSDGRRAEDYGFFCRAACSEGVVAAREVCIVSDVRRKTDVRFFRETFGE 123
Query: 125 VTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHG 172
+TVR+VA E++R +RGW F GVDD +SEC LD+ ++D ++EN
Sbjct: 124 RVRTVRIVAGEETRTERGWKFQQGVDDVQSECDLDDVTEWDLLVENEA 171
>gb|EDM00623.1| phosphomevalonate kinase, isoform CRA_d [Rattus norvegicus]
Length = 83
Score = 137 bits (344), Expect = 5e-31, Method: Composition-based stats.
Identities = 68/81 (83%), Positives = 76/81 (93%)
Query: 112 VSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENH 171
+SDIQWF+EAYGA+TQTVRVVA EQSRQQRGWVFT GVDDAESECGLD+FGDFDWVIENH
Sbjct: 1 MSDIQWFQEAYGALTQTVRVVASEQSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENH 60
Query: 172 GVEQRLEEQLENLIEFIRSRL 192
G EQ LE+QLENL+EFI ++L
Sbjct: 61 GDEQCLEDQLENLLEFIHAKL 81
>ref|NP_872133.1| F32D8.13 [Caenorhabditis elegans]
emb|CAD66220.1| Hypothetical protein F32D8.13 [Caenorhabditis elegans]
Length = 187
Score = 137 bits (344), Expect = 5e-31, Method: Composition-based stats.
Identities = 79/185 (42%), Positives = 110/185 (59%), Gaps = 13/185 (7%)
Query: 10 LVLLFSGKRKSGKDFVTEAL-----QSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLD 64
+V+ SGKRKSGKD+ T + Q R V + S LK ++A++HGL ++ LL
Sbjct: 3 IVIAISGKRKSGKDYCTNLIREVLVQKRFDVSVAGI---SHSLKMEFAKKHGLKYEELLT 59
Query: 65 TSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEG-ISQPIWLVSDTRRVSDIQWFREAYG 123
YKE +RKDMI+WGEE R D G FCR + + I ++SD RR +D ++F Y
Sbjct: 60 DGPYKELYRKDMIQWGEEARCKDSGLFCRAAISSTMDSDIVIISDCRRRTDYEYFSANYR 119
Query: 124 AVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLEN 183
V T+R+ E+ R+QRG+ F GVDDAESECGLD++ F+ VI+N L +QL
Sbjct: 120 TV--TIRIETSEEDRKQRGYQFVEGVDDAESECGLDDY-KFNLVIKNQSGTD-LSQQLNM 175
Query: 184 LIEFI 188
+ E I
Sbjct: 176 VTEKI 180
>emb|CAF95044.1| unnamed protein product [Tetraodon nigroviridis]
Length = 114
Score = 129 bits (324), Expect = 1e-28, Method: Composition-based stats.
Identities = 61/114 (53%), Positives = 80/114 (70%)
Query: 76 MIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALE 135
MI WGE +R+ADPGFFCR + QP+W+VSD RR+SD+QWF+ + TQ VRV +
Sbjct: 1 MIHWGETRRRADPGFFCRLATKEAWQPVWVVSDARRLSDVQWFQAEFPQQTQLVRVGCSD 60
Query: 136 QSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIR 189
++RQQRGW FT GVDD+ESECGLD FDW++ N L+EQL+ L++ R
Sbjct: 61 RTRQQRGWSFTAGVDDSESECGLDTGVQFDWIVNNDAGGASLDEQLQPLLKLAR 114
>gb|AAP06404.1| similar to GenBank Accession Number AP001507 tRNA/rRNA
methyltransferase in Bacillus halodurans [Schistosoma
japonicum]
Length = 125
Score = 93.2 bits (230), Expect = 9e-18, Method: Composition-based stats.
Identities = 49/117 (41%), Positives = 75/117 (64%), Gaps = 9/117 (7%)
Query: 10 LVLLFSGKRKSGKDFVTEALQSRLGADVCA--VLRLSGPLKEQYAQEHGLNFQRLLDTST 67
+ ++FSGKRKSGKD+ L + L ++ + V+R+S P+K +A+ +GLN LL ++
Sbjct: 7 ICVVFSGKRKSGKDYTVNHLTNLLQSNHLSYLVVRISEPIKSYFAEHYGLNLSELLSSNE 66
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIV------EGISQPIW-LVSDTRRVSDIQW 117
YKE +RK MI W E++ + DP F RK + GISQP ++SD RRV+DI++
Sbjct: 67 YKENYRKQMISWMEQEIKQDPYVFIRKSLLESTRRHGISQPAGIIISDARRVNDIEY 123
>ref|XP_001892529.1| phosphomevalonate kinase [Brugia malayi]
gb|EDP38638.1| phosphomevalonate kinase, putative [Brugia malayi]
Length = 103
Score = 82.8 bits (203), Expect = 1e-14, Method: Composition-based stats.
Identities = 44/89 (49%), Positives = 58/89 (65%), Gaps = 4/89 (4%)
Query: 10 LVLLFSGKRKSGKDFVTEALQSRL---GADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
+V+ SGKRK GKDFV L +RL G V + +S PLKE+YAQ +G++ +RL +
Sbjct: 4 VVICLSGKRKCGKDFVGSLLANRLERIGYKVI-ICGISYPLKEEYAQLNGIDAERLKYDA 62
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKI 95
YKE +R+DMI WGE R D G+FCR I
Sbjct: 63 QYKEIYRQDMISWGEGIRSHDSGYFCRLI 91
>ref|YP_278526.1| hypothetical protein MS53_0403 [Mycoplasma synoviae 53]
gb|AAZ43815.1| hypothetical protein MS53_0403 [Mycoplasma synoviae 53]
Length = 207
Score = 46.6 bits (109), Expect = 9e-04, Method: Composition-based stats.
Identities = 47/195 (24%), Positives = 87/195 (44%), Gaps = 25/195 (12%)
Query: 11 VLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKE 70
++L +GKR+SGK ++ AL+ ++ V S + A E + Q+L KE
Sbjct: 5 IILINGKRRSGKGILSSALKDQIQKFSSNVYIFSFAESIRKAAEDII--QKLNWEKEPKE 62
Query: 71 AFRKDMIRWGEEKRQADPGFFCRKIVEGISQPI-----------WLVSDTRRVSDIQWFR 119
R +I G+ R+ D F+ K+ E I + I +++ D R +++ +F+
Sbjct: 63 TTRPLLIAIGDVGRKIDSDFWSIKLFEQIQEKINLAEQNNQDSYYIIDDLRITNELNFFK 122
Query: 120 EAYGAVTQ-----TVRVVALEQSRQQRGWVFTPGVDDAESECGLDN--FGDFDWVIENHG 172
+ Q + V+++ + F G DD +E D+ + FD++IE +
Sbjct: 123 KNEILFNQENSISELNVISIRIQKYLDASNFIHGTDDNITETSFDDVVYSSFDYIIEGNV 182
Query: 173 VEQRLEEQLENLIEF 187
+ Q+ E L EF
Sbjct: 183 IVQK-----EGLAEF 192
>ref|XP_001801140.1| hypothetical protein SNOG_10882 [Phaeosphaeria nodorum SN15]
gb|EAT81381.2| hypothetical protein SNOG_10882 [Phaeosphaeria nodorum SN15]
Length = 1625
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 45/174 (25%), Positives = 69/174 (39%), Gaps = 17/174 (9%)
Query: 7 APRLVLLFSGKRKSGKDFVTEALQS--------RLGADVCAVLRLSGPLKEQYAQEHGLN 58
P+L+ L +G +GKD+ E S RL + ++ S K YA G +
Sbjct: 684 GPKLIFLVTGNHGAGKDYCAEQWASEVKDHARERLEVHISSI---SDATKRAYAASTGAD 740
Query: 59 FQRLLDTSTYKEAFRKDMIRWGEEKRQADPGF----FCRKIVEGISQPIWLVSDTRRVSD 114
RLL+ YKE R M + + + Q P F + + ++ R +
Sbjct: 741 LARLLNDRAYKEQHRAAMTAFFKAQVQQRPNLPEEHFLDVVYGAAEADVLFITGMRDPAP 800
Query: 115 IQWFREAY-GAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECG-LDNFGDFDW 166
+ F G+ VRV A E+ R PGV + E+ LD DFD+
Sbjct: 801 VAMFSHLVPGSRVIEVRVRASEEIIYNRRCCDGPGVAERETASALLDWCPDFDF 854
>ref|XP_001517271.1| PREDICTED: similar to phosphomevalonate kinase, partial
[Ornithorhynchus anatinus]
Length = 30
Score = 44.3 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 20/30 (66%), Positives = 22/30 (73%), Gaps = 1/30 (3%)
Query: 76 MIRWGEEKRQADPGFFCRKIVE-GISQPIW 104
MI WGEE+R+ DPGFFCR V G QPIW
Sbjct: 1 MILWGEERRRRDPGFFCRAAVAGGFPQPIW 30
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|NP_001008353.1| phosphomevalonate kinase [Rattus norveg... 352 6e-96
ref|XP_001497725.1| PREDICTED: similar to phosphomevalonate... 352 7e-96
sp|Q9D1G2|PMVK_MOUSE Phosphomevalonate kinase (PMKase) >gi|... 352 8e-96
dbj|BAE40294.1| unnamed protein product [Mus musculus] >gi|... 351 2e-95
gb|AAQ02411.1| phosphomevalonate kinase [synthetic construct] 350 3e-95
gb|AAV38778.1| phosphomevalonate kinase [synthetic construc... 350 4e-95
ref|NP_006547.1| phosphomevalonate kinase [Homo sapiens] >g... 350 4e-95
ref|NP_001039616.1| phosphomevalonate kinase [Bos taurus] >... 350 4e-95
gb|AAV38779.1| phosphomevalonate kinase [Homo sapiens] >gi|... 350 4e-95
gb|AAX37126.1| phosphomevalonate kinase [synthetic construct] 349 6e-95
ref|XP_001114509.1| PREDICTED: phosphomevalonate kinase [Ma... 349 6e-95
ref|NP_081060.1| phosphomevalonate kinase [Mus musculus] >g... 348 8e-95
ref|XP_513842.2| PREDICTED: phosphomevalonate kinase [Pan t... 347 3e-94
gb|EDL15190.1| phosphomevalonate kinase, isoform CRA_a [Mus... 342 1e-92
ref|XP_855082.1| PREDICTED: similar to Phosphomevalonate ki... 335 1e-90
ref|XP_001373420.1| PREDICTED: similar to Phosphomevalonate... 325 1e-87
dbj|BAB28875.1| unnamed protein product [Mus musculus] >gi|... 293 4e-78
ref|NP_001077048.1| phosphomevalonate kinase [Danio rerio] ... 288 1e-76
ref|XP_689489.2| PREDICTED: similar to Phosphomevalonate ki... 288 2e-76
gb|AAC60791.1| phosphomevalonate kinase [Homo sapiens] 285 1e-75
ref|XP_001120920.1| PREDICTED: similar to Phosphomevalonate... 267 3e-70
dbj|BAF62110.1| phosphomevalonate kinase [Bombyx mori] 266 4e-70
ref|XP_001748282.1| predicted protein [Monosiga brevicollis... 266 5e-70
ref|NP_001040145.1| phosphomevalonate kinase [Bombyx mori] ... 261 3e-68
ref|XP_001604440.1| PREDICTED: similar to phosphomevalonate... 259 5e-68
ref|XP_310779.4| AGAP000338-PA [Anopheles gambiae str. PEST... 259 6e-68
gb|EDM00620.1| phosphomevalonate kinase, isoform CRA_a [Rat... 256 7e-67
ref|XP_974268.1| PREDICTED: similar to Phosphomevalonate ki... 255 1e-66
ref|XP_001635081.1| predicted protein [Nematostella vectens... 254 3e-66
gb|AAW26333.1| SJCHGC02790 protein [Schistosoma japonicum] 252 1e-65
ref|XP_001357257.1| GA10206-PA [Drosophila pseudoobscura] >... 240 4e-62
sp|Q29081|PMVK_PIG Phosphomevalonate kinase (PMKase) 238 2e-61
ref|XP_001664006.1| phosphomevalonate kinase, putative [Aed... 237 4e-61
gb|AAM51057.1| SD12705p [Drosophila melanogaster] 235 1e-60
ref|NP_609992.1| CG10268 CG10268-PA [Drosophila melanogaste... 234 2e-60
gb|ABF18214.1| phosphomevalonate kinase [Aedes aegypti] 234 3e-60
ref|NP_001089752.1| hypothetical protein LOC734816 [Xenopus... 230 4e-59
ref|XP_001866014.1| phosphomevalonate kinase [Culex pipiens... 226 6e-58
ref|NP_872133.1| F32D8.13 [Caenorhabditis elegans] >gi|2831... 223 4e-57
ref|XP_001673885.1| Hypothetical protein CBG09742 [Caenorha... 219 6e-56
gb|AAH28659.1| Pmvk protein [Mus musculus] 217 3e-55
gb|EDM00621.1| phosphomevalonate kinase, isoform CRA_b [Rat... 216 9e-55
gb|AAC37331.1| phosphomevalonate kinase 191 2e-47
ref|XP_001801140.1| hypothetical protein SNOG_10882 [Phaeos... 190 4e-47
ref|YP_278526.1| hypothetical protein MS53_0403 [Mycoplasma... 173 5e-42
emb|CAF95044.1| unnamed protein product [Tetraodon nigrovir... 170 3e-41
gb|AAP06404.1| similar to GenBank Accession Number AP001507... 151 3e-35
gb|EDM00623.1| phosphomevalonate kinase, isoform CRA_d [Rat... 146 7e-34
ref|XP_001892529.1| phosphomevalonate kinase [Brugia malayi... 120 6e-26
Sequences not found previously or not previously below threshold:
ref|XP_001270504.1| phosphoribosyl transferase domain prote... 129 1e-28
ref|XP_001818778.1| hypothetical protein [Aspergillus oryza... 120 5e-26
ref|XP_359731.1| hypothetical protein MGG_05046 [Magnaporth... 117 6e-25
ref|XP_001211374.1| conserved hypothetical protein [Aspergi... 117 6e-25
ref|XP_001907258.1| unnamed protein product [Podospora anse... 116 8e-25
ref|XP_001224477.1| hypothetical protein CHGG_06821 [Chaeto... 115 2e-24
gb|EDU43013.1| 6-hydroxy-D-nicotine oxidase [Pyrenophora tr... 108 2e-22
ref|XP_001559442.1| hypothetical protein BC1G_02106 [Botryo... 97 7e-19
ref|XP_383779.1| hypothetical protein FG03603.1 [Gibberella... 96 1e-18
ref|XP_001598716.1| hypothetical protein SS1G_00805 [Sclero... 92 2e-17
gb|ABA40789.1| SJCHGC02791 protein [Schistosoma japonicum] 58 3e-07
ref|YP_189074.1| hypothetical protein SERP1509 [Staphylococ... 50 1e-04
ref|NP_041167.1| ORF77 [Ictalurid herpesvirus 1] >gi|138108... 48 4e-04
ref|XP_001517271.1| PREDICTED: similar to phosphomevalonate... 47 5e-04
ref|NP_047943.1| gp52 [Streptomyces phage phiC31] >gi|39474... 47 0.001
gb|ABX64470.1| putative deoxynucleotide monophosphate kinas... 45 0.002
ref|YP_001642759.1| adenylate kinase-like protein [Bacillus... 45 0.003
ref|ZP_02327437.1| adenylate kinase and related kinases [Pa... 45 0.004
ref|ZP_02443545.1| hypothetical protein ANACOL_02862 [Anaer... 42 0.021
ref|ZP_00998993.1| 23S rRNA (Uracil-5-)-methyltransferase r... 41 0.042
ref|NP_041166.1| ORF76 [Ictalurid herpesvirus 1] >gi|138107... 41 0.048
emb|CAI64255.1| hypothetical protein [uncultured archaeon] 40 0.061
ref|NP_813711.1| gp52 [Streptomyces phage phiBT1] >gi|29243... 40 0.075
ref|NP_899571.1| dNMP kinase [Vibrio phage KVP40] >gi|34333... 40 0.11
ref|YP_920099.1| dephospho-CoA kinase [Thermofilum pendens ... 39 0.14
ref|ZP_03960517.1| dephospho-CoA kinase [Lactobacillus vagi... 39 0.21
ref|XP_385614.1| hypothetical protein FG05438.1 [Gibberella... 39 0.21
ref|YP_001533397.1| hypothetical protein Dshi_2059 [Dinoros... 39 0.21
ref|NP_613685.1| Dephospho-CoA kinase [Methanopyrus kandler... 38 0.29
ref|ZP_03981046.1| conserved hypothetical protein [Enteroco... 38 0.34
ref|XP_001387102.1| negative growth regulatory protein [Pic... 38 0.46
gb|EAZ63079.2| negative growth regulatory protein [Pichia s... 38 0.46
ref|YP_447603.1| predicted dephospho-CoA kinase [Methanosph... 37 0.60
ref|YP_001736520.1| Dephospho-CoA kinase [Candidatus Korarc... 37 0.66
ref|XP_001486586.1| hypothetical protein PGUG_02257 [Pichia... 37 0.73
emb|CAL54296.1| unnamed protein product [Ostreococcus tauri] 37 0.75
ref|YP_001671779.1| ATP-binding protein [Enterobacteria pha... 37 0.95
ref|YP_001789537.1| recA protein [Leptothrix cholodnii SP-6... 37 0.98
ref|YP_001019272.1| putative recombinase A [Methylibium pet... 37 1.0
ref|YP_532190.1| ABC transporter related [Rhodopseudomonas ... 36 1.2
ref|ZP_02015288.1| dephospho-CoA kinase [Halorubrum lacuspr... 36 1.2
ref|YP_570089.1| ABC transporter related [Rhodopseudomonas ... 36 1.3
ref|YP_984172.1| recA protein [Polaromonas naphthalenivoran... 36 1.4
ref|XP_001305657.1| hypothetical protein TVAG_329880 [Trich... 36 1.4
ref|NP_108493.1| hypothetical protein mlr8387 [Mesorhizobiu... 36 1.4
ref|YP_566773.1| hypothetical protein Mbur_2153 [Methanococ... 36 1.5
ref|YP_001630497.1| cmk [Bordetella petrii DSM 12804] >gi|1... 36 1.6
gb|AAN74113.1| RecA [Helicobacter pylori] >gi|25808109|gb|A... 35 1.9
gb|AAN74106.1| RecA [Helicobacter pylori] 35 1.9
ref|YP_966498.1| hypothetical protein Dvul_1051 [Desulfovib... 35 2.0
ref|NP_281051.1| hypothetical protein VNG2452C [Halobacteri... 35 2.0
ref|ZP_00603651.1| hypothetical protein EfaeDRAFT_1703 [Ent... 35 2.2
ref|XP_719886.1| hypothetical protein CaO19_6790 [Candida a... 35 2.5
ref|ZP_01643088.1| hypothetical protein SmalDRAFT_0847 [Ste... 35 3.0
ref|XP_001267110.1| mannosyltransferase, putative [Neosarto... 35 3.0
ref|YP_486100.1| ABC transporter related [Rhodopseudomonas ... 35 3.1
ref|YP_023587.1| hypothetical protein PTO0809 [Picrophilus ... 35 3.3
ref|ZP_01110362.1| hypothetical protein MADE_17737 [Alterom... 35 3.6
gb|AAN74121.1| RecA [Helicobacter pylori] 35 3.7
ref|NP_611097.2| CG8446 CG8446-PA [Drosophila melanogaster]... 35 3.7
gb|AAN74117.1| RecA [Helicobacter pylori] 35 3.7
gb|AAN74143.1| RecA [Helicobacter pylori] 35 3.7
gb|AAN74144.1| RecA [Helicobacter pylori] 35 3.7
ref|YP_001350712.1| probable carbonic anhydrase [Pseudomona... 35 3.7
ref|XP_001802070.1| hypothetical protein SNOG_11833 [Phaeos... 35 3.7
gb|AAN74129.1| RecA [Helicobacter pylori] 35 3.7
gb|AAN74116.1| RecA [Helicobacter pylori] 35 3.8
gb|AAT49796.1| PA4676 [synthetic construct] 35 3.8
gb|AAP39983.1| RecA [Helicobacter acinonychis] 35 3.8
ref|NP_253365.1| probable carbonic anhydrase [Pseudomonas a... 35 3.8
gb|AAN74124.1| RecA [Helicobacter pylori] 35 3.8
gb|AAP39985.1| RecA [Helicobacter acinonychis] >gi|30961735... 35 3.8
emb|CAA84615.1| RecA [Helicobacter pylori] 35 3.8
gb|AAN74159.1| RecA [Helicobacter pylori] 35 3.9
gb|AAN74152.1| RecA [Helicobacter pylori] >gi|25808191|gb|A... 35 3.9
gb|ABW91113.1| RecA [Rhodobacter sp. DQ12-45T] 35 4.0
gb|ABW91114.1| RecA [Rhodobacter sphaeroides] 35 4.0
gb|AAN74125.1| RecA [Helicobacter pylori] >gi|25808139|gb|A... 35 4.0
gb|AAN74107.1| RecA [Helicobacter pylori] 35 4.0
ref|YP_262312.1| carbonic anhydrase [Pseudomonas fluorescen... 35 4.0
gb|AAN74112.1| RecA [Helicobacter pylori] 35 4.1
gb|AAN74135.1| RecA [Helicobacter pylori] 35 4.1
gb|AAN74131.1| RecA [Helicobacter pylori] >gi|25808163|gb|A... 35 4.1
gb|AAP39984.1| RecA [Helicobacter acinonychis] 35 4.1
ref|ZP_01626946.1| hypothetical protein MGP2080_04625 [mari... 34 4.1
gb|ABW91115.1| RecA [Rhodobaca bogoriensis] 34 4.2
ref|ZP_02927948.1| Carbonate dehydratase [Verrucomicrobium ... 34 4.5
gb|ABY83966.1| putative deoxycytidylate deaminase [Brucella... 34 4.5
ref|ZP_02012413.1| Carbonate dehydratase [Opitutaceae bacte... 34 4.7
ref|ZP_01708195.1| hypothetical protein Faci_03001859 [Ferr... 34 4.7
ref|NP_012020.1| Peroxisomal integral membrane peroxin, inv... 34 4.7
gb|EDN62389.1| peroxin [Saccharomyces cerevisiae YJM789] 34 4.7
gb|AAK96212.1|AF405550_1 recombinase [Helicobacter pylori] 34 4.7
gb|AAN74130.1| RecA [Helicobacter pylori] 34 5.0
gb|AAO73330.1| recombinase [Helicobacter pylori] 34 5.2
gb|AAO73331.1| recombinase [Helicobacter pylori] 34 5.3
ref|NP_248402.1| alignment in /usr/local/projects/ARG/Inter... 34 5.5
ref|YP_551466.1| recA protein [Polaromonas sp. JS666] >gi|9... 34 5.6
ref|YP_001595273.1| gp1 dNMP kinase [Enterobacteria phage J... 34 5.8
ref|ZP_01745615.1| recombinase A [Sagittula stellata E-37] ... 34 5.8
ref|YP_001861350.1| Carboxymuconolactone decarboxylase [Bur... 34 5.9
ref|ZP_02727315.1| hypothetical protein CdifQCD_06240 [Clos... 34 6.3
gb|AAM93532.1| RecA protein [Rickettsia typhi] 34 6.5
ref|YP_353525.1| recombinase A [Rhodobacter sphaeroides 2.4... 34 6.6
sp|P32725|RECA_RHOS4 Protein recA (Recombinase A) >gi|28834... 34 6.6
gb|EEH97608.1| predicted protein [Clostridium sp. 7_2_43FAA] 34 6.9
gb|AAN74137.1| RecA [Helicobacter pylori] 33 7.1
ref|YP_001532986.1| recA protein [Dinoroseobacter shibae DF... 33 7.1
ref|ZP_02065541.1| hypothetical protein BACOVA_02523 [Bacte... 33 7.3
gb|AAN74133.1| RecA [Helicobacter pylori] 33 7.7
gb|AAN74126.1| RecA [Helicobacter pylori] 33 7.7
gb|AAN74161.1| RecA [Helicobacter pylori] 33 7.7
gb|AAN74114.1| RecA [Helicobacter pylori] 33 7.7
gb|AAN74115.1| RecA [Helicobacter pylori] 33 7.8
gb|AAN74132.1| RecA [Helicobacter pylori] 33 7.8
gb|AAN74158.1| RecA [Helicobacter pylori] 33 7.9
gb|AAN74128.1| RecA [Helicobacter pylori] 33 7.9
ref|YP_001909645.1| recombinase A [Helicobacter pylori Shi4... 33 8.0
ref|NP_206952.1| recombinase A [Helicobacter pylori 26695] ... 33 8.0
ref|YP_664174.1| recombinase A [Helicobacter acinonychis st... 33 8.0
gb|AAL37303.1|AF323925_1 recombinase RecA [Helicobacter pyl... 33 8.2
ref|YP_626892.1| recombinase A [Helicobacter pylori HPAG1] ... 33 8.2
ref|NP_641936.1| carbonic anhydrase [Xanthomonas axonopodis... 33 8.3
gb|AAN74108.1| RecA [Helicobacter pylori] >gi|25808089|gb|A... 33 8.3
gb|AAN74105.1| RecA [Helicobacter pylori] >gi|25808091|gb|A... 33 8.3
ref|NP_342513.1| Adenylate kinase related protein (adkA-lik... 33 8.4
gb|AAN74140.1| RecA [Helicobacter pylori] 33 8.4
gb|AAN74123.1| RecA [Helicobacter pylori] 33 8.4
ref|ZP_02299667.1| ABC transporter related [Rhodopseudomona... 33 8.4
gb|ABW74998.1| RecA [Rhizobium sp. CCBAU 83490] 33 8.5
ref|ZP_01160632.1| putative Carbonic anhydrase [Photobacter... 33 8.7
ref|NP_948396.1| ABC transporter, duplicated ATPase domains... 33 8.7
gb|AAO73328.1| recombinase [Helicobacter pylori] >gi|309591... 33 8.7
ref|YP_363377.1| carbonic anhydrase [Xanthomonas campestris... 33 8.8
ref|YP_523833.1| ABC transporter related [Rhodoferax ferrir... 33 8.8
gb|AAM93531.1| RecA protein [Rickettsia honei] 33 8.8
ref|YP_001325008.1| hypothetical protein Maeo_0813 [Methano... 33 8.9
ref|ZP_01236068.1| putative Carbonic anhydrase [Vibrio angu... 33 9.2
sp|P95469|RECA_PARDE Protein recA (Recombinase A) >gi|18254... 33 9.5
ref|YP_201062.1| carbonic anhydrase [Xanthomonas oryzae pv.... 33 9.5
ref|YP_067686.1| recombinase A [Rickettsia typhi str. Wilmi... 33 9.6
>ref|NP_001008353.1| phosphomevalonate kinase [Rattus norvegicus]
gb|AAH86349.1| Phosphomevalonate kinase [Rattus norvegicus]
gb|EDM00622.1| phosphomevalonate kinase, isoform CRA_c [Rattus norvegicus]
Length = 194
Score = 352 bits (905), Expect = 6e-96, Method: Composition-based stats.
Identities = 164/192 (85%), Positives = 181/192 (94%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE LQSRLG ++CAVLRLSGPLKEQYA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLQSRLGGNICAVLRLSGPLKEQYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
+LLD STYKE +R+DMI WGEEKRQADPGFFCRKIVEG+SQPIWLVSDTRR+SDIQWF+E
Sbjct: 61 KLLDASTYKETYRRDMICWGEEKRQADPGFFCRKIVEGVSQPIWLVSDTRRMSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVA EQSRQQRGWVFT GVDDAESECGLD+FGDFDWVIENHG EQ LE+Q
Sbjct: 121 AYGALTQTVRVVASEQSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LENL+EFI ++L
Sbjct: 181 LENLLEFIHAKL 192
>ref|XP_001497725.1| PREDICTED: similar to phosphomevalonate kinase [Equus caballus]
Length = 192
Score = 352 bits (904), Expect = 7e-96, Method: Composition-based stats.
Identities = 178/192 (92%), Positives = 186/192 (96%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEA QSRLGADVCA+LRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEAPQSRLGADVCAILRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKEA+R+DMIRWGEEKRQADPGFFCRKIVEG+SQP+WLVSDTRRVSDIQWF+E
Sbjct: 61 RLLDASTYKEAYRRDMIRWGEEKRQADPGFFCRKIVEGVSQPVWLVSDTRRVSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
YGA+TQT+RVVALEQSRQQRGWVFTPGVDDAESECGLDNFG FDWVIENHG EQRLEEQ
Sbjct: 121 TYGAMTQTIRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGGFDWVIENHGDEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFI SRL
Sbjct: 181 LENLIEFIHSRL 192
>sp|Q9D1G2|PMVK_MOUSE Phosphomevalonate kinase (PMKase)
gb|EDL15192.1| phosphomevalonate kinase, isoform CRA_c [Mus musculus]
Length = 192
Score = 352 bits (904), Expect = 8e-96, Method: Composition-based stats.
Identities = 160/192 (83%), Positives = 180/192 (93%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE +R+DMI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+E
Sbjct: 61 RLLDASTYKETYRRDMICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAV QTVRVVA EQSRQQRGWVFTPGVDDAESECGLDNFG+FDWVIENHG EQ LE+Q
Sbjct: 121 AYGAVIQTVRVVASEQSRQQRGWVFTPGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LE+L+ FI+++L
Sbjct: 181 LEHLLGFIQAKL 192
>dbj|BAE40294.1| unnamed protein product [Mus musculus]
dbj|BAE29599.1| unnamed protein product [Mus musculus]
Length = 192
Score = 351 bits (901), Expect = 2e-95, Method: Composition-based stats.
Identities = 160/192 (83%), Positives = 179/192 (93%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE +R DMI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+E
Sbjct: 61 RLLDASTYKETYRGDMICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAV QTVRVVA EQSRQQRGWVFTPGVDDAESECGLDNFG+FDWVIENHG EQ LE+Q
Sbjct: 121 AYGAVIQTVRVVASEQSRQQRGWVFTPGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LE+L+ FI+++L
Sbjct: 181 LEHLLGFIQAKL 192
>gb|AAQ02411.1| phosphomevalonate kinase [synthetic construct]
Length = 193
Score = 350 bits (899), Expect = 3e-95, Method: Composition-based stats.
Identities = 192/192 (100%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>gb|AAV38778.1| phosphomevalonate kinase [synthetic construct]
gb|AAX42912.1| phosphomevalonate kinase [synthetic construct]
gb|AAX42913.1| phosphomevalonate kinase [synthetic construct]
gb|AAX42914.1| phosphomevalonate kinase [synthetic construct]
Length = 193
Score = 350 bits (898), Expect = 4e-95, Method: Composition-based stats.
Identities = 191/192 (99%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAMTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>ref|NP_006547.1| phosphomevalonate kinase [Homo sapiens]
sp|Q15126|PMVK_HUMAN Phosphomevalonate kinase (PMKase)
gb|AAC37593.1| phosphomevalonate kinase
gb|AAH06089.1| Phosphomevalonate kinase [Homo sapiens]
gb|AAH07694.1| Phosphomevalonate kinase [Homo sapiens]
emb|CAG46795.1| PMVK [Homo sapiens]
emb|CAI13237.1| phosphomevalonate kinase [Homo sapiens]
gb|EAW53177.1| phosphomevalonate kinase, isoform CRA_a [Homo sapiens]
gb|EAW53178.1| phosphomevalonate kinase, isoform CRA_a [Homo sapiens]
Length = 192
Score = 350 bits (898), Expect = 4e-95, Method: Composition-based stats.
Identities = 192/192 (100%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>ref|NP_001039616.1| phosphomevalonate kinase [Bos taurus]
sp|Q2KIU2|PMVK_BOVIN Phosphomevalonate kinase (PMKase)
gb|AAI12510.1| Phosphomevalonate kinase [Bos taurus]
Length = 192
Score = 350 bits (898), Expect = 4e-95, Method: Composition-based stats.
Identities = 173/192 (90%), Positives = 182/192 (94%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGG P LVLLFSGKRKSGKDFVTEALQSRLGADVCA+LRLSGPLKEQYAQEHGL+FQ
Sbjct: 1 MAPLGGVPGLVLLFSGKRKSGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RL+D STYKEA+R DMIRWGEEKRQADPGFFCRKIVEG+ QP+WLVSDTRRVSDIQWF+E
Sbjct: 61 RLMDASTYKEAYRSDMIRWGEEKRQADPGFFCRKIVEGVCQPVWLVSDTRRVSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVA E+SRQQRGWVFTPGVDDAESECGLDNF FDWVIENHG EQ LEEQ
Sbjct: 121 AYGAVTQTVRVVATEESRQQRGWVFTPGVDDAESECGLDNFRTFDWVIENHGDEQHLEEQ 180
Query: 181 LENLIEFIRSRL 192
LE+LIEFIRSRL
Sbjct: 181 LEHLIEFIRSRL 192
>gb|AAV38779.1| phosphomevalonate kinase [Homo sapiens]
gb|AAX41326.1| phosphomevalonate kinase [synthetic construct]
gb|AAX41327.1| phosphomevalonate kinase [synthetic construct]
gb|AAX41328.1| phosphomevalonate kinase [synthetic construct]
Length = 192
Score = 350 bits (898), Expect = 4e-95, Method: Composition-based stats.
Identities = 191/192 (99%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAMTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>gb|AAX37126.1| phosphomevalonate kinase [synthetic construct]
Length = 193
Score = 349 bits (896), Expect = 6e-95, Method: Composition-based stats.
Identities = 192/192 (100%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>ref|XP_001114509.1| PREDICTED: phosphomevalonate kinase [Macaca mulatta]
Length = 192
Score = 349 bits (896), Expect = 6e-95, Method: Composition-based stats.
Identities = 187/192 (97%), Positives = 188/192 (97%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPL GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLAGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDASTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFG FDWVIENHG EQRLEEQ
Sbjct: 121 AYGAMTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGGFDWVIENHGDEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>ref|NP_081060.1| phosphomevalonate kinase [Mus musculus]
dbj|BAB22886.1| unnamed protein product [Mus musculus]
Length = 192
Score = 348 bits (895), Expect = 8e-95, Method: Composition-based stats.
Identities = 159/192 (82%), Positives = 179/192 (93%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE +R+DMI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+E
Sbjct: 61 RLLDASTYKETYRRDMICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAV QTVRVVA EQSRQQRGWVFT GVDDAESECGLDNFG+FDWVIENHG EQ LE+Q
Sbjct: 121 AYGAVIQTVRVVASEQSRQQRGWVFTLGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LE+L+ FI+++L
Sbjct: 181 LEHLLGFIQAKL 192
>ref|XP_513842.2| PREDICTED: phosphomevalonate kinase [Pan troglodytes]
Length = 192
Score = 347 bits (891), Expect = 3e-94, Method: Composition-based stats.
Identities = 189/192 (98%), Positives = 189/192 (98%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVT ALQS LGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTXALQSXLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQ LEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQHLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>gb|EDL15190.1| phosphomevalonate kinase, isoform CRA_a [Mus musculus]
Length = 206
Score = 342 bits (877), Expect = 1e-92, Method: Composition-based stats.
Identities = 161/206 (78%), Positives = 180/206 (87%), Gaps = 14/206 (6%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYA-------- 52
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREGWWDCV 60
Query: 53 ------QEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLV 106
QEHGL+FQRLLD STYKE +R+DMI WGE+KRQADPGFFCRKIVEG+SQPIWLV
Sbjct: 61 IDGLALQEHGLDFQRLLDASTYKETYRRDMICWGEQKRQADPGFFCRKIVEGVSQPIWLV 120
Query: 107 SDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDW 166
SDTRR SDIQWF+EAYGAV QTVRVVA EQSRQQRGWVFTPGVDDAESECGLDNFG+FDW
Sbjct: 121 SDTRRTSDIQWFQEAYGAVIQTVRVVASEQSRQQRGWVFTPGVDDAESECGLDNFGNFDW 180
Query: 167 VIENHGVEQRLEEQLENLIEFIRSRL 192
VIENHG EQ LE+QLE+L+ FI+++L
Sbjct: 181 VIENHGDEQCLEDQLEHLLGFIQAKL 206
>ref|XP_855082.1| PREDICTED: similar to Phosphomevalonate kinase (PMKase) [Canis
familiaris]
Length = 192
Score = 335 bits (859), Expect = 1e-90, Method: Composition-based stats.
Identities = 168/192 (87%), Positives = 178/192 (92%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAP GGAP LVLL SGKRKSGKDFV EAL+SRLGADVCAVLRLSGPLKEQYA+EH L+FQ
Sbjct: 1 MAPRGGAPCLVLLVSGKRKSGKDFVAEALRSRLGADVCAVLRLSGPLKEQYAKEHDLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD S YKEAFR+DMIRWGEEKRQADPGFFCRK+VEG+ QP+WLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDASAYKEAFRRDMIRWGEEKRQADPGFFCRKVVEGVFQPVWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVA EQSRQQRGWVFT GVDDAESECGLDNFG FDWVIENHG EQRLEEQ
Sbjct: 121 AYGALTQTVRVVASEQSRQQRGWVFTTGVDDAESECGLDNFGAFDWVIENHGDEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LE L+ F+RSRL
Sbjct: 181 LEKLVVFVRSRL 192
>ref|XP_001373420.1| PREDICTED: similar to Phosphomevalonate kinase [Monodelphis
domestica]
Length = 204
Score = 325 bits (833), Expect = 1e-87, Method: Composition-based stats.
Identities = 149/192 (77%), Positives = 172/192 (89%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAP +PRLVLLFSGKRKSGKDFVT+ L+SRLG DVCAVLRLSGPLKEQYA+EHGL+FQ
Sbjct: 1 MAPRVDSPRLVLLFSGKRKSGKDFVTDELRSRLGTDVCAVLRLSGPLKEQYAKEHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD S+YKEAFR+DMIRWGEEKR+ADPGFFCRKIVEG+ QP+WLVSDTRR SDI WF+
Sbjct: 61 RLLDASSYKEAFRQDMIRWGEEKREADPGFFCRKIVEGVPQPVWLVSDTRRESDIHWFQA 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
++G VTQ VRVVA E+SR+QRGWVFT GVDDAESECGLD+F FDWVIENHG +++LE+Q
Sbjct: 121 SFGDVTQLVRVVASEESRRQRGWVFTAGVDDAESECGLDHFEAFDWVIENHGEDRKLEQQ 180
Query: 181 LENLIEFIRSRL 192
L L++FI S+L
Sbjct: 181 LGKLVDFIHSKL 192
>dbj|BAB28875.1| unnamed protein product [Mus musculus]
gb|EDL15191.1| phosphomevalonate kinase, isoform CRA_b [Mus musculus]
Length = 171
Score = 293 bits (752), Expect = 4e-78, Method: Composition-based stats.
Identities = 133/163 (81%), Positives = 152/163 (93%)
Query: 30 QSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPG 89
+RLG ++CA+LRLSGPLKE+YA+EHGL+FQRLLD STYKE +R+DMI WGE+KRQADPG
Sbjct: 9 YARLGGNICALLRLSGPLKEEYAREHGLDFQRLLDASTYKETYRRDMICWGEQKRQADPG 68
Query: 90 FFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGV 149
FFCRKIVEG+SQPIWLVSDTRR SDIQWF+EAYGAV QTVRVVA EQSRQQRGWVFTPGV
Sbjct: 69 FFCRKIVEGVSQPIWLVSDTRRTSDIQWFQEAYGAVIQTVRVVASEQSRQQRGWVFTPGV 128
Query: 150 DDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
DDAESECGLDNFG+FDWVIENHG EQ LE+QLE+L+ FI+++L
Sbjct: 129 DDAESECGLDNFGNFDWVIENHGDEQCLEDQLEHLLGFIQAKL 171
>ref|NP_001077048.1| phosphomevalonate kinase [Danio rerio]
ref|XP_689711.2| PREDICTED: similar to Phosphomevalonate kinase [Danio rerio]
gb|AAI35046.1| Zgc:162701 protein [Danio rerio]
Length = 199
Score = 288 bits (739), Expect = 1e-76, Method: Composition-based stats.
Identities = 102/185 (55%), Positives = 139/185 (75%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
P ++LLFSGKRKSGKD+VT+ +Q RL A++C +LRLS PLKEQYA++H L+++ L+ +
Sbjct: 6 PSIILLFSGKRKSGKDYVTDLIQKRLTAEICCILRLSAPLKEQYAKDHNLDYEELMGSGQ 65
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQ 127
YKE++R DMI WGE KRQ D GFFCR ++ +QP+W++SD RR+SD+QWFREA+
Sbjct: 66 YKESYRADMIHWGEMKRQEDSGFFCRLAIKHATQPVWIISDCRRMSDVQWFREAFPNKCV 125
Query: 128 TVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEF 187
VRV A EQ+R +RGW FT G+DDAESECGLD FD +I N G + LE+ L+ L+
Sbjct: 126 CVRVEASEQTRSERGWRFTSGIDDAESECGLDEGVKFDRIIRNDGSDDILEKHLDELLSS 185
Query: 188 IRSRL 192
+RS++
Sbjct: 186 VRSQV 190
>ref|XP_689489.2| PREDICTED: similar to Phosphomevalonate kinase [Danio rerio]
Length = 199
Score = 288 bits (738), Expect = 2e-76, Method: Composition-based stats.
Identities = 102/185 (55%), Positives = 139/185 (75%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
P ++LLFSGKRKSGKD+VT+ +Q RL A++C +LRLS PLKEQYA++H L+++ L+ +
Sbjct: 6 PSIILLFSGKRKSGKDYVTDLIQKRLTAEMCCILRLSAPLKEQYAKDHNLDYEELMGSGQ 65
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQ 127
YKE++R DMI WGE KRQ D GFFCR ++ +QP+W++SD RR+SD+QWFREA+
Sbjct: 66 YKESYRADMIHWGEMKRQEDSGFFCRLAIKHATQPVWIISDCRRMSDVQWFREAFPNKCV 125
Query: 128 TVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEF 187
VRV A EQ+R +RGW FT G+DDAESECGLD FD +I N G + LE+ L+ L+
Sbjct: 126 CVRVEASEQTRSERGWRFTSGIDDAESECGLDEGVKFDRIIRNDGSDDILEKHLDELLSS 185
Query: 188 IRSRL 192
+RS++
Sbjct: 186 VRSQV 190
>gb|AAC60791.1| phosphomevalonate kinase [Homo sapiens]
Length = 160
Score = 285 bits (730), Expect = 1e-75, Method: Composition-based stats.
Identities = 160/160 (100%), Positives = 160/160 (100%)
Query: 33 LGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFC 92
LGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFC
Sbjct: 1 LGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFC 60
Query: 93 RKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDA 152
RKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDA
Sbjct: 61 RKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDA 120
Query: 153 ESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
ESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL
Sbjct: 121 ESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 160
>ref|XP_001120920.1| PREDICTED: similar to Phosphomevalonate kinase (PMKase) [Apis
mellifera]
Length = 202
Score = 267 bits (683), Expect = 3e-70, Method: Composition-based stats.
Identities = 76/186 (40%), Positives = 118/186 (63%), Gaps = 5/186 (2%)
Query: 6 GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDT 65
P+++LLFSGKRK GKD++T L R+G+D ++++S P+K +A+ HGLN +L+
Sbjct: 18 SKPKIILLFSGKRKCGKDYITNILYERIGSDNSVIIKISAPIKSHWAKSHGLNIDQLMGD 77
Query: 66 STYKEAFRKDMIRWGEEKRQADPGFFCRK---IVEGISQPIWLVSDTRRVSDIQWFREAY 122
YKE +R +M +WGE R D G+FCR I + IW+VSD RR +DIQWF E +
Sbjct: 78 GKYKENYRLEMAKWGENIRNTDQGYFCRAALDIYNAYDKSIWIVSDIRRKTDIQWFTENF 137
Query: 123 GAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLE 182
+ +T+R+ + + R +RGW F G+DDAE+EC LD+ +D + N+ + +E L+
Sbjct: 138 KDICKTIRIESDDSIRIERGWTFVTGIDDAETECDLDDVNTWDLKVTNN--TKSIECILQ 195
Query: 183 NLIEFI 188
++E I
Sbjct: 196 QILELI 201
>dbj|BAF62110.1| phosphomevalonate kinase [Bombyx mori]
Length = 186
Score = 266 bits (682), Expect = 4e-70, Method: Composition-based stats.
Identities = 85/183 (46%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Query: 7 APRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
+P+++LLFSGKRKSGKDF+T+ L+ L AD C ++++S P+K +A+E LN LL
Sbjct: 2 SPKIILLFSGKRKSGKDFLTDHLRHIL-ADKCEIIKISQPIKTHWAKEKNLNLNELLSEG 60
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGIS-QPIWLVSDTRRVSDIQWFREAYGAV 125
YKE +R +MI+W EE R D G FC+ E + +P+W+VSD RR +DI+WF+E YG +
Sbjct: 61 EYKEQYRLEMIKWSEEMRNKDYGCFCKAACENAAIKPVWIVSDIRRKTDIRWFKETYGDI 120
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLI 185
+TVR+ A +++R++RG+ F GVDDA SEC LD++ D+D V+ N LEEQL++++
Sbjct: 121 IRTVRITADDRTRKERGFQFQVGVDDATSECDLDDYNDWDVVVNNGEGRDSLEEQLDSIL 180
Query: 186 EFI 188
+ +
Sbjct: 181 KLV 183
>ref|XP_001748282.1| predicted protein [Monosiga brevicollis MX1]
gb|EDQ87043.1| predicted protein [Monosiga brevicollis MX1]
Length = 234
Score = 266 bits (681), Expect = 5e-70, Method: Composition-based stats.
Identities = 99/186 (53%), Positives = 120/186 (64%), Gaps = 4/186 (2%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLG-ADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
P+LVLLFSGKRKSGKD++ + L R A V A +RLS PLK QYA +HGL++Q LL S
Sbjct: 51 PKLVLLFSGKRKSGKDYLADQLAQRPDLAPVLAQVRLSAPLKRQYALDHGLDYQELLSAS 110
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVT 126
TYKE R+ MI WGE+KR+ADPGFF R + PIWLV D RR +D+ +F+ Y
Sbjct: 111 TYKEQHRQAMIVWGEQKRRADPGFFARLATHDLQAPIWLVVDCRRQTDLTYFQTRYP--C 168
Query: 127 QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIE 186
TVRV A +R QRG+ FT GVDDAESECGLD D VI+N G Q L+ L+
Sbjct: 169 VTVRVQASVATRAQRGYTFTTGVDDAESECGLDAV-QHDIVIDNDGDGQATAAALDQLLA 227
Query: 187 FIRSRL 192
I L
Sbjct: 228 QIHQSL 233
>ref|NP_001040145.1| phosphomevalonate kinase [Bombyx mori]
gb|ABD36154.1| phosphomevalonate kinase [Bombyx mori]
Length = 186
Score = 261 bits (667), Expect = 3e-68, Method: Composition-based stats.
Identities = 84/183 (45%), Positives = 127/183 (69%), Gaps = 2/183 (1%)
Query: 7 APRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
+P+++LLFSGKRKSGKDF+T+ L+ L AD C ++++S P+K +A+E LN LL
Sbjct: 2 SPKIILLFSGKRKSGKDFLTDHLRHIL-ADKCEIIKISQPIKTHWAKEKNLNLNELLSEG 60
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGIS-QPIWLVSDTRRVSDIQWFREAYGAV 125
YKE +R +MI+W EE R D G FC+ E + +P+W+VSD RR +DI+WF+E YG +
Sbjct: 61 EYKEQYRLEMIKWSEEMRNKDYGCFCKAACENAAIKPVWIVSDIRRKTDIRWFKETYGDI 120
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLI 185
+TVR+ A +++R++RG+ F GVDDA SEC LD++ D D V+ N LEE L++++
Sbjct: 121 IRTVRITADDRTRKERGFQFQVGVDDATSECDLDDYNDGDVVVNNGEGRDSLEEPLDSIL 180
Query: 186 EFI 188
+ +
Sbjct: 181 KLV 183
>ref|XP_001604440.1| PREDICTED: similar to phosphomevalonate kinase [Nasonia
vitripennis]
Length = 204
Score = 259 bits (664), Expect = 5e-68, Method: Composition-based stats.
Identities = 76/184 (41%), Positives = 121/184 (65%), Gaps = 5/184 (2%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
P +L+FSGKRKSGKDF+T+ L +RLG + +++LSGP+K +A+ L+ ++L
Sbjct: 22 PEKILIFSGKRKSGKDFITDELFARLGKEKSVIIKLSGPIKSHWAKIKNLDAKQLFGDGE 81
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKI---VEGISQPIWLVSDTRRVSDIQWFREAYGA 124
YKEA+R++M +WGE+ R D G+FCR +PIW++SD RR +D++WF+E Y
Sbjct: 82 YKEAYRREMTKWGEDTRNKDYGYFCRAAILMYNANDKPIWIISDARRKTDLKWFKEHYAD 141
Query: 125 VTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENL 184
+T+R+ + E+ R+ RGW F G+DD+E+EC LD+ +D I N+G + +E L +
Sbjct: 142 KCKTIRISSSEEVRKNRGWKFCRGIDDSETECDLDDVTYWDLEINNNGED--IELILHEI 199
Query: 185 IEFI 188
I+ +
Sbjct: 200 IDIL 203
>ref|XP_310779.4| AGAP000338-PA [Anopheles gambiae str. PEST]
gb|EAA06245.5| AGAP000338-PA [Anopheles gambiae str. PEST]
Length = 192
Score = 259 bits (664), Expect = 6e-68, Method: Composition-based stats.
Identities = 86/185 (46%), Positives = 118/185 (63%), Gaps = 3/185 (1%)
Query: 6 GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDT 65
G PR++LL SGKRK GKDF+ +AL RLG D ++R+S P+K +A+ GL+ LL
Sbjct: 7 GVPRVLLLLSGKRKCGKDFLADALLQRLGTDRAQIVRISEPIKRHWAEAMGLDLAALLGD 66
Query: 66 STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAV 125
YKE +R+ MI W + +RQ D G FCR I +PI +VSD RR +D+++FREAYG
Sbjct: 67 GAYKERYRRQMIEWSDGRRQEDYGVFCRAACATIDRPICIVSDVRRQTDVRYFREAYGPE 126
Query: 126 T--QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLEN 183
T +TVR+ A EQ R RGW F GVDD +SEC LD + +D V+ N + + E L+
Sbjct: 127 TRLRTVRIEASEQVRHGRGWQFQAGVDDVQSECDLDGYAGWDLVLTNERPD-GVGELLDR 185
Query: 184 LIEFI 188
L++ I
Sbjct: 186 LVQLI 190
>gb|EDM00620.1| phosphomevalonate kinase, isoform CRA_a [Rattus norvegicus]
Length = 147
Score = 256 bits (654), Expect = 7e-67, Method: Composition-based stats.
Identities = 119/140 (85%), Positives = 132/140 (94%)
Query: 53 QEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRV 112
QEHGL+FQ+LLD STYKE +R+DMI WGEEKRQADPGFFCRKIVEG+SQPIWLVSDTRR+
Sbjct: 6 QEHGLDFQKLLDASTYKETYRRDMICWGEEKRQADPGFFCRKIVEGVSQPIWLVSDTRRM 65
Query: 113 SDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHG 172
SDIQWF+EAYGA+TQTVRVVA EQSRQQRGWVFT GVDDAESECGLD+FGDFDWVIENHG
Sbjct: 66 SDIQWFQEAYGALTQTVRVVASEQSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENHG 125
Query: 173 VEQRLEEQLENLIEFIRSRL 192
EQ LE+QLENL+EFI ++L
Sbjct: 126 DEQCLEDQLENLLEFIHAKL 145
>ref|XP_974268.1| PREDICTED: similar to Phosphomevalonate kinase (PMKase) [Tribolium
castaneum]
Length = 189
Score = 255 bits (652), Expect = 1e-66, Method: Composition-based stats.
Identities = 88/186 (47%), Positives = 123/186 (66%), Gaps = 6/186 (3%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGL---NFQRLLD 64
PRL+LLFSGKRKSGKD++ EAL++ LG + C ++R+SGPLK YA+ H L + ++
Sbjct: 4 PRLILLFSGKRKSGKDYICEALKANLGDNNCTIIRISGPLKRLYAESHDLTTGDVNEMMT 63
Query: 65 TSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGIS-QPIWLVSDTRRVSDIQWFREAYG 123
KE FR +MI+W +E R D GFFC+ + +P W+VSD RR +DI WF+ Y
Sbjct: 64 DGPLKEKFRAEMIQWSDEIRGRDFGFFCKAATDLADLKPFWIVSDIRRKTDIHWFKNTYK 123
Query: 124 AVTQ-TVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLE 182
+R+ A E +RQ+RGWVFT GVDD SEC LD+F D+D +I+N+ E+ L E L
Sbjct: 124 DKIIKLIRIQADEVTRQKRGWVFTEGVDDVTSECDLDDFSDWDLIIKNNNAEE-LGEGLG 182
Query: 183 NLIEFI 188
L++F+
Sbjct: 183 KLMQFL 188
>ref|XP_001635081.1| predicted protein [Nematostella vectensis]
gb|EDO43018.1| predicted protein [Nematostella vectensis]
Length = 192
Score = 254 bits (649), Expect = 3e-66, Method: Composition-based stats.
Identities = 95/192 (49%), Positives = 129/192 (67%), Gaps = 9/192 (4%)
Query: 4 LGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLL 63
+ P V + SGKRKSGKD+V E L+ LG C +LRLSGPLK +YA+ H L++Q+LL
Sbjct: 1 MAAKPFAVCILSGKRKSGKDYVAERLKILLGKSNCEILRLSGPLKREYARIHKLDYQKLL 60
Query: 64 DTSTYKEAFRKDMIRWGEEKRQADPGFFCRKI-------VEGISQPIWLVSDTRRVSDIQ 116
D+S YKE +RKDMI+WGEEKR A+P +FC + ++ WLVSD RR++D+Q
Sbjct: 61 DSSDYKEKYRKDMIKWGEEKRNAEPYYFCELAAKMAYRDAQSETKLYWLVSDARRITDLQ 120
Query: 117 WFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQR 176
+F++ Y V VRV A + R +RGW+FT GVDDAESECGLD+ FD I N+G ++
Sbjct: 121 FFQQHYPRVVH-VRVTASDDVRMRRGWMFTNGVDDAESECGLDDV-IFDVAIINNGDNEQ 178
Query: 177 LEEQLENLIEFI 188
LE L +L + +
Sbjct: 179 LENSLASLKDKL 190
>gb|AAW26333.1| SJCHGC02790 protein [Schistosoma japonicum]
Length = 202
Score = 252 bits (644), Expect = 1e-65, Method: Composition-based stats.
Identities = 76/193 (39%), Positives = 121/193 (62%), Gaps = 10/193 (5%)
Query: 10 LVLLFSGKRKSGKDFVTEALQSRLGADVCA--VLRLSGPLKEQYAQEHGLNFQRLLDTST 67
+ ++FSGKRKSGKD+ L + L ++ + V+R+S P+K +A+ +GLN LL ++
Sbjct: 7 ICVVFSGKRKSGKDYTVNHLTNLLQSNHLSYLVVRISEPIKSYFAEHYGLNLSELLSSNE 66
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIV------EGISQP-IWLVSDTRRVSDIQWFRE 120
YKE +RK MI W E++ + DP F RK + GISQP + ++SD RRV+DI++ +
Sbjct: 67 YKENYRKQMISWMEQEIKQDPYVFIRKSLLESTRRHGISQPAVIIISDARRVNDIEYLIK 126
Query: 121 AYG-AVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEE 179
+G + VR+VA + R +RGW + GVD+A SECGLD F ++D+++ N+G + E
Sbjct: 127 TFGRSKCLLVRIVAPIEIRTERGWTYVNGVDNAASECGLDEFTNWDYIVSNNGDKSVFEN 186
Query: 180 QLENLIEFIRSRL 192
L ++ I+ L
Sbjct: 187 HLHVIVAHIKRML 199
>ref|XP_001357257.1| GA10206-PA [Drosophila pseudoobscura]
gb|EAL34326.1| GA10206-PA [Drosophila pseudoobscura]
Length = 185
Score = 240 bits (614), Expect = 4e-62, Method: Composition-based stats.
Identities = 76/182 (41%), Positives = 116/182 (63%), Gaps = 6/182 (3%)
Query: 11 VLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKE 70
++L SGKRK GKD+++E LQ RL + ++R+S P+K ++A++ L+ LL YKE
Sbjct: 4 IVLISGKRKCGKDYISERLQKRL-TNRAIIVRISEPIKSEWARKLQLDLSALLSDGPYKE 62
Query: 71 AFRKDMIRWGEEKRQADPGFFCRKIVEGISQP---IWLVSDTRRVSDIQWFREAYGA-VT 126
+R+DMI W +E R D G+FCR +E +VSD RR +DI+WFRE YG +
Sbjct: 63 QYRRDMIVWSDEVRSKDYGYFCRAAMEEAPLDQIAYVIVSDVRRKNDIKWFRETYGQNMV 122
Query: 127 QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGV-EQRLEEQLENLI 185
+TVR+ + ++RQ RGW FT G+DD SEC LD++ FD+V+ N +Q +QL +++
Sbjct: 123 RTVRLTSRPETRQARGWTFTKGIDDVPSECDLDDYDSFDFVVPNEDENDQGFIDQLLDML 182
Query: 186 EF 187
+
Sbjct: 183 QL 184
>sp|Q29081|PMVK_PIG Phosphomevalonate kinase (PMKase)
Length = 130
Score = 238 bits (608), Expect = 2e-61, Method: Composition-based stats.
Identities = 116/129 (89%), Positives = 124/129 (96%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG PRLVLLFSGKRK GKDFVTEALQSRLGADVCA+LRLSGPLKEQYAQEHGL+FQ
Sbjct: 1 MAPLGSVPRLVLLFSGKRKDGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE++RKDMIRWG+EKRQADPGFFCRKIVEG+SQPIWLVSDTRR+SDIQWF+E
Sbjct: 61 RLLDASTYKESYRKDMIRWGQEKRQADPGFFCRKIVEGVSQPIWLVSDTRRLSDIQWFQE 120
Query: 121 AYGAVTQTV 129
YGAVTQTV
Sbjct: 121 TYGAVTQTV 129
>ref|XP_001664006.1| phosphomevalonate kinase, putative [Aedes aegypti]
gb|EAT33914.1| phosphomevalonate kinase, putative [Aedes aegypti]
Length = 187
Score = 237 bits (605), Expect = 4e-61, Method: Composition-based stats.
Identities = 84/183 (45%), Positives = 122/183 (66%), Gaps = 1/183 (0%)
Query: 7 APRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
PR+VLLFSGKRK GKDF+TE L RL D ++R+S P+K +A++ GL+ LL
Sbjct: 6 VPRVVLLFSGKRKCGKDFLTERLLQRLTTDKAQIIRISEPIKRSWAEKLGLDLGELLGDG 65
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVT 126
YKE +RK+MI W ++KR D GFFCR+ +++ I +VSD RR +D+++FRE YG
Sbjct: 66 PYKERYRKEMIEWSDQKRAEDFGFFCRQACLALAKEICVVSDIRRKTDVRFFREQYGQRI 125
Query: 127 QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIE 186
+TVR+VA E +R +RGWVF GVDD +SEC LD+ ++D +++N +E L +I
Sbjct: 126 KTVRIVASEATRVERGWVFQEGVDDVQSECDLDDVTEWDLLVQNDSGAD-VENILARIIA 184
Query: 187 FIR 189
++
Sbjct: 185 LVQ 187
>gb|AAM51057.1| SD12705p [Drosophila melanogaster]
Length = 189
Score = 235 bits (600), Expect = 1e-60, Method: Composition-based stats.
Identities = 81/188 (43%), Positives = 113/188 (60%), Gaps = 13/188 (6%)
Query: 11 VLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKE 70
++L SGKRK GKD+++E LQ RLG+ C ++R+S P+K ++A + L+ LL YKE
Sbjct: 4 IVLISGKRKCGKDYISERLQRRLGSRSC-IVRISEPIKSEWAHKLQLDLDALLGDGPYKE 62
Query: 71 AFRKDMIRWGEEKRQADPGFFCRKIVEGI----SQPIWLVSDTRRVSDIQWFREAYGA-V 125
+R+DMI W +E R D G+FCR +E P LVSD RR +DI+WFRE YG
Sbjct: 63 KYRRDMIVWSDEVRAQDYGYFCRVAMEEALSRQQTPYILVSDVRRKNDIRWFRETYGPER 122
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGD-FDWVIENHGVEQRLEEQLENL 184
T+R+ + ++R RGW FT G+DD SEC LD+ D FD V+ N EE +
Sbjct: 123 VITLRLTSRPETRSARGWTFTAGIDDVPSECDLDDLADGFDVVLAND------EELDQEA 176
Query: 185 IEFIRSRL 192
I+ + RL
Sbjct: 177 IDILLDRL 184
>ref|NP_609992.1| CG10268 CG10268-PA [Drosophila melanogaster]
sp|Q9VIT2|PMVK_DROME Probable phosphomevalonate kinase (PMKase)
gb|AAF53833.1| CG10268-PA [Drosophila melanogaster]
Length = 189
Score = 234 bits (599), Expect = 2e-60, Method: Composition-based stats.
Identities = 81/188 (43%), Positives = 114/188 (60%), Gaps = 13/188 (6%)
Query: 11 VLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKE 70
++L SGKRK GKD+++E LQ RLG+ C ++R+S P+K ++A++ L+ LL YKE
Sbjct: 4 IVLISGKRKCGKDYISERLQRRLGSRSC-IVRISEPIKSEWARKLQLDLDALLGDGPYKE 62
Query: 71 AFRKDMIRWGEEKRQADPGFFCRKIVEGI----SQPIWLVSDTRRVSDIQWFREAYGA-V 125
+R+DMI W +E R D G+FCR +E P LVSD RR +DI+WFRE YG
Sbjct: 63 KYRRDMIVWSDEVRAQDYGYFCRVAMEEALSRQQTPYILVSDVRRKNDIRWFRETYGPER 122
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGD-FDWVIENHGVEQRLEEQLENL 184
T+R+ + ++R RGW FT G+DD SEC LD+ D FD V+ N EE +
Sbjct: 123 VITLRLTSRPETRSARGWTFTAGIDDVPSECDLDDLADGFDVVLAND------EELDQEA 176
Query: 185 IEFIRSRL 192
I+ + RL
Sbjct: 177 IDILLDRL 184
>gb|ABF18214.1| phosphomevalonate kinase [Aedes aegypti]
Length = 187
Score = 234 bits (597), Expect = 3e-60, Method: Composition-based stats.
Identities = 82/184 (44%), Positives = 120/184 (65%), Gaps = 1/184 (0%)
Query: 6 GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDT 65
PR+VLLF GKRK GKDF+TE L RL D ++R+S P+K +A++ GL+ LL
Sbjct: 5 AVPRVVLLFFGKRKCGKDFLTERLLQRLTTDKAQIIRISEPIKRSWAEKLGLDLGELLGD 64
Query: 66 STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAV 125
YKE +RK+MI W ++KR D GFFCR+ +++ I +VSD RR +D+++FRE YG
Sbjct: 65 GPYKERYRKEMIEWSDQKRAEDFGFFCRQACLALAKEICVVSDIRRKTDVRFFREQYGQR 124
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLI 185
+TVR+VA E +R +RGWVF GVDD +SEC LD+ ++D +++N +E L ++
Sbjct: 125 IKTVRIVASEATRVERGWVFQEGVDDVQSECDLDDVTEWDLLVQNDSGAD-VENILARIV 183
Query: 186 EFIR 189
+
Sbjct: 184 ALAQ 187
>ref|NP_001089752.1| hypothetical protein LOC734816 [Xenopus laevis]
gb|AAI06478.1| MGC131201 protein [Xenopus laevis]
Length = 145
Score = 230 bits (587), Expect = 4e-59, Method: Composition-based stats.
Identities = 99/143 (69%), Positives = 117/143 (81%)
Query: 6 GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDT 65
G PRLVLLFSGKRKSGKD VT +LQ R +D C+VLRLSGPLKEQ+A E GL+++RLL
Sbjct: 2 GEPRLVLLFSGKRKSGKDHVTNSLQLRFSSDTCSVLRLSGPLKEQFALERGLDYERLLGA 61
Query: 66 STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAV 125
+ YKE FR DMIRWGEEKR+ DPGFFCR IV+ +SQP+W++SD RR SDI WFR YGAV
Sbjct: 62 TGYKEEFRADMIRWGEEKRRRDPGFFCRIIVQRVSQPVWIISDARRKSDIDWFRSEYGAV 121
Query: 126 TQTVRVVALEQSRQQRGWVFTPG 148
QTVRV A E++R+ RGWV+TPG
Sbjct: 122 LQTVRVEASEETREARGWVYTPG 144
>ref|XP_001866014.1| phosphomevalonate kinase [Culex pipiens quinquefasciatus]
gb|EDS42634.1| phosphomevalonate kinase [Culex pipiens quinquefasciatus]
Length = 186
Score = 226 bits (577), Expect = 6e-58, Method: Composition-based stats.
Identities = 78/188 (41%), Positives = 116/188 (61%), Gaps = 8/188 (4%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
PR+VLLFSGKRK GKD++TE L RL ++R+S P+K +A + GL+ LL
Sbjct: 4 PRIVLLFSGKRKCGKDYLTERLLQRLTPARAQIVRISEPIKRCWADKLGLDLGELLGDGP 63
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEG---ISQPIWLVSDTRRVSDIQWFREAYGA 124
YKE +R++MI W + +R D GFFCR ++ + +VSD RR +D+++FRE +G
Sbjct: 64 YKERYRREMIEWSDGRRAEDYGFFCRAACSEGVVAAREVCIVSDVRRKTDVRFFRETFGE 123
Query: 125 VTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENL 184
+TVR+VA E++R +RGW F GVDD +SEC LD+ ++D ++EN E +
Sbjct: 124 RVRTVRIVAGEETRTERGWKFQQGVDDVQSECDLDDVTEWDLLVENEAGADV-----EGI 178
Query: 185 IEFIRSRL 192
+ I + L
Sbjct: 179 LARIEALL 186
>ref|NP_872133.1| F32D8.13 [Caenorhabditis elegans]
emb|CAD66220.1| Hypothetical protein F32D8.13 [Caenorhabditis elegans]
Length = 187
Score = 223 bits (570), Expect = 4e-57, Method: Composition-based stats.
Identities = 78/184 (42%), Positives = 111/184 (60%), Gaps = 7/184 (3%)
Query: 10 LVLLFSGKRKSGKDFVTEALQSRL--GADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
+V+ SGKRKSGKD+ T ++ L +V +S LK ++A++HGL ++ LL
Sbjct: 3 IVIAISGKRKSGKDYCTNLIREVLVQKRFDVSVAGISHSLKMEFAKKHGLKYEELLTDGP 62
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEG-ISQPIWLVSDTRRVSDIQWFREAYGAVT 126
YKE +RKDMI+WGEE R D G FCR + + I ++SD RR +D ++F Y T
Sbjct: 63 YKELYRKDMIQWGEEARCKDSGLFCRAAISSTMDSDIVIISDCRRRTDYEYFSANY--RT 120
Query: 127 QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIE 186
T+R+ E+ R+QRG+ F GVDDAESECGLD++ F+ VI+N L +QL + E
Sbjct: 121 VTIRIETSEEDRKQRGYQFVEGVDDAESECGLDDY-KFNLVIKNQSGTD-LSQQLNMVTE 178
Query: 187 FIRS 190
I
Sbjct: 179 KISR 182
>ref|XP_001673885.1| Hypothetical protein CBG09742 [Caenorhabditis briggsae AF16]
Length = 188
Score = 219 bits (560), Expect = 6e-56, Method: Composition-based stats.
Identities = 81/166 (48%), Positives = 106/166 (63%), Gaps = 8/166 (4%)
Query: 9 RLVLLFSGKRKSGKDFVTEAL---QSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDT 65
+ V+ SGKRKSGKD+ T L ++ V AV +S LKE+YA+ H LNF LL
Sbjct: 3 KFVIAISGKRKSGKDYCTNKLIKAFEKIQLSVSAV-GISHSLKEEYAKIHNLNFAELLTD 61
Query: 66 STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGI-SQPIWLVSDTRRVSDIQWFREAYGA 124
YKE FRKDMIRWGE+ R P FCR + + I +VSD RR++D+++F Y
Sbjct: 62 GPYKEQFRKDMIRWGEDVRNKIPSVFCRAALLSVDDSDIVIVSDCRRITDLEFFVSNY-- 119
Query: 125 VTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIEN 170
T TVRV +E+ RQQRG+ F G+DDAESECGLD++ FD V++N
Sbjct: 120 KTLTVRVETIEEHRQQRGFRFVKGIDDAESECGLDDY-KFDVVLKN 164
>gb|AAH28659.1| Pmvk protein [Mus musculus]
Length = 117
Score = 217 bits (554), Expect = 3e-55, Method: Composition-based stats.
Identities = 100/117 (85%), Positives = 110/117 (94%)
Query: 76 MIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALE 135
MI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+EAYGAV QTVRVVA E
Sbjct: 1 MICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQEAYGAVIQTVRVVASE 60
Query: 136 QSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
QSRQQRGWVFTPGVDDAESECGLDNFG+FDWVIENHG EQ LE+QLE+L+ FI+++L
Sbjct: 61 QSRQQRGWVFTPGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQLEHLLGFIQAKL 117
>gb|EDM00621.1| phosphomevalonate kinase, isoform CRA_b [Rattus norvegicus]
Length = 119
Score = 216 bits (550), Expect = 9e-55, Method: Composition-based stats.
Identities = 102/117 (87%), Positives = 111/117 (94%)
Query: 76 MIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALE 135
MI WGEEKRQADPGFFCRKIVEG+SQPIWLVSDTRR+SDIQWF+EAYGA+TQTVRVVA E
Sbjct: 1 MICWGEEKRQADPGFFCRKIVEGVSQPIWLVSDTRRMSDIQWFQEAYGALTQTVRVVASE 60
Query: 136 QSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
QSRQQRGWVFT GVDDAESECGLD+FGDFDWVIENHG EQ LE+QLENL+EFI ++L
Sbjct: 61 QSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENHGDEQCLEDQLENLLEFIHAKL 117
>gb|AAC37331.1| phosphomevalonate kinase
Length = 106
Score = 191 bits (486), Expect = 2e-47, Method: Composition-based stats.
Identities = 95/106 (89%), Positives = 103/106 (97%)
Query: 16 GKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKD 75
GKRK GKDFVTEALQSRLGADVCA+LRLSGPLKEQYAQEHGL+FQRLLD STYKE++RKD
Sbjct: 1 GKRKDGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQRLLDASTYKESYRKD 60
Query: 76 MIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREA 121
MIRWG+EKRQADPGFFCRKIVEG+SQPIWLVSDTRR+SDIQWF+E
Sbjct: 61 MIRWGQEKRQADPGFFCRKIVEGVSQPIWLVSDTRRLSDIQWFQET 106
>ref|XP_001801140.1| hypothetical protein SNOG_10882 [Phaeosphaeria nodorum SN15]
gb|EAT81381.2| hypothetical protein SNOG_10882 [Phaeosphaeria nodorum SN15]
Length = 1625
Score = 190 bits (484), Expect = 4e-47, Method: Composition-based stats.
Identities = 46/180 (25%), Positives = 72/180 (40%), Gaps = 19/180 (10%)
Query: 7 APRLVLLFSGKRKSGKDFVTEALQS--------RLGADVCAVLRLSGPLKEQYAQEHGLN 58
P+L+ L +G +GKD+ E S RL + ++ S K YA G +
Sbjct: 684 GPKLIFLVTGNHGAGKDYCAEQWASEVKDHARERLEVHISSI---SDATKRAYAASTGAD 740
Query: 59 FQRLLDTSTYKEAFRKDMIRWGEEKRQADPGF----FCRKIVEGISQPIWLVSDTRRVSD 114
RLL+ YKE R M + + + Q P F + + ++ R +
Sbjct: 741 LARLLNDRAYKEQHRAAMTAFFKAQVQQRPNLPEEHFLDVVYGAAEADVLFITGMRDPAP 800
Query: 115 IQWFREAY-GAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECG-LDNFGDFDWVIENHG 172
+ F G+ VRV A E+ R PGV + E+ LD DFD+ +N+
Sbjct: 801 VAMFSHLVPGSRVIEVRVRASEEIIYNRRCCDGPGVAERETASALLDWCPDFDF--DNNV 858
>ref|YP_278526.1| hypothetical protein MS53_0403 [Mycoplasma synoviae 53]
gb|AAZ43815.1| hypothetical protein MS53_0403 [Mycoplasma synoviae 53]
Length = 207
Score = 173 bits (440), Expect = 5e-42, Method: Composition-based stats.
Identities = 47/195 (24%), Positives = 87/195 (44%), Gaps = 25/195 (12%)
Query: 11 VLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKE 70
++L +GKR+SGK ++ AL+ ++ V S + A E + Q+L KE
Sbjct: 5 IILINGKRRSGKGILSSALKDQIQKFSSNVYIFSFAESIRKAAEDII--QKLNWEKEPKE 62
Query: 71 AFRKDMIRWGEEKRQADPGFFCRKIVEGISQPI-----------WLVSDTRRVSDIQWFR 119
R +I G+ R+ D F+ K+ E I + I +++ D R +++ +F+
Sbjct: 63 TTRPLLIAIGDVGRKIDSDFWSIKLFEQIQEKINLAEQNNQDSYYIIDDLRITNELNFFK 122
Query: 120 EAYGAVTQ-----TVRVVALEQSRQQRGWVFTPGVDDAESECGLDN--FGDFDWVIENHG 172
+ Q + V+++ + F G DD +E D+ + FD++IE +
Sbjct: 123 KNEILFNQENSISELNVISIRIQKYLDASNFIHGTDDNITETSFDDVVYSSFDYIIEGNV 182
Query: 173 VEQRLEEQLENLIEF 187
+ Q+ E L EF
Sbjct: 183 IVQK-----EGLAEF 192
>emb|CAF95044.1| unnamed protein product [Tetraodon nigroviridis]
Length = 114
Score = 170 bits (433), Expect = 3e-41, Method: Composition-based stats.
Identities = 61/114 (53%), Positives = 80/114 (70%)
Query: 76 MIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALE 135
MI WGE +R+ADPGFFCR + QP+W+VSD RR+SD+QWF+ + TQ VRV +
Sbjct: 1 MIHWGETRRRADPGFFCRLATKEAWQPVWVVSDARRLSDVQWFQAEFPQQTQLVRVGCSD 60
Query: 136 QSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIR 189
++RQQRGW FT GVDD+ESECGLD FDW++ N L+EQL+ L++ R
Sbjct: 61 RTRQQRGWSFTAGVDDSESECGLDTGVQFDWIVNNDAGGASLDEQLQPLLKLAR 114
>gb|AAP06404.1| similar to GenBank Accession Number AP001507 tRNA/rRNA
methyltransferase in Bacillus halodurans [Schistosoma
japonicum]
Length = 125
Score = 151 bits (382), Expect = 3e-35, Method: Composition-based stats.
Identities = 49/117 (41%), Positives = 75/117 (64%), Gaps = 9/117 (7%)
Query: 10 LVLLFSGKRKSGKDFVTEALQSRLGADVCA--VLRLSGPLKEQYAQEHGLNFQRLLDTST 67
+ ++FSGKRKSGKD+ L + L ++ + V+R+S P+K +A+ +GLN LL ++
Sbjct: 7 ICVVFSGKRKSGKDYTVNHLTNLLQSNHLSYLVVRISEPIKSYFAEHYGLNLSELLSSNE 66
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIV------EGISQPI-WLVSDTRRVSDIQW 117
YKE +RK MI W E++ + DP F RK + GISQP ++SD RRV+DI++
Sbjct: 67 YKENYRKQMISWMEQEIKQDPYVFIRKSLLESTRRHGISQPAGIIISDARRVNDIEY 123
>gb|EDM00623.1| phosphomevalonate kinase, isoform CRA_d [Rattus norvegicus]
Length = 83
Score = 146 bits (370), Expect = 7e-34, Method: Composition-based stats.
Identities = 68/81 (83%), Positives = 76/81 (93%)
Query: 112 VSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENH 171
+SDIQWF+EAYGA+TQTVRVVA EQSRQQRGWVFT GVDDAESECGLD+FGDFDWVIENH
Sbjct: 1 MSDIQWFQEAYGALTQTVRVVASEQSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENH 60
Query: 172 GVEQRLEEQLENLIEFIRSRL 192
G EQ LE+QLENL+EFI ++L
Sbjct: 61 GDEQCLEDQLENLLEFIHAKL 81
>ref|XP_001270504.1| phosphoribosyl transferase domain protein [Aspergillus clavatus
NRRL 1]
gb|EAW09078.1| phosphoribosyl transferase domain protein [Aspergillus clavatus
NRRL 1]
Length = 1164
Score = 129 bits (324), Expect = 1e-28, Method: Composition-based stats.
Identities = 48/217 (22%), Positives = 85/217 (39%), Gaps = 32/217 (14%)
Query: 3 PLGGAP---RLVLLFSGKRKSGKDFVTEALQS--------RLGADVCAVLRLSGPLKEQY 51
PL P +L++L +G +GKD+ E S RL A ++ S K +Y
Sbjct: 762 PLPETPVETKLIILVTGDSCAGKDYCAEIWVSAFTEYAHKRLTARSVSI---SDATKREY 818
Query: 52 AQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGF----FCRKIVEGISQPIWLVS 107
A + G + RL+ YKE R + + +++ Q P F + + + L++
Sbjct: 819 AAQTGADLNRLIRDRAYKEQHRPALTSFFQDQVQHRPQLLQEHFLDVVHGAVDVDVLLIT 878
Query: 108 DTRRVSDIQWFREAYG-AVTQTVRVVALEQSRQQRGWVFTPGVDDAESE---------CG 157
R + + + VRV A E++R+ R + G D +++
Sbjct: 879 GMRDEAPVAGLSHLVPDSRLLDVRVQASEETRRARRGCCSSGDDRNDNKDSNNGGLNPTA 938
Query: 158 LDNFGDFDWVIENHGVEQRLEEQL--ENLIEFIRSRL 192
LD F + +N ++L E L+ F L
Sbjct: 939 LDYRPSF--IFKNDAPGDEAAKKLAEERLLPFFHEDL 973
>ref|XP_001818778.1| hypothetical protein [Aspergillus oryzae RIB40]
dbj|BAE56776.1| unnamed protein product [Aspergillus oryzae]
Length = 1159
Score = 120 bits (302), Expect = 5e-26, Method: Composition-based stats.
Identities = 35/146 (23%), Positives = 59/146 (40%), Gaps = 10/146 (6%)
Query: 9 RLVLLFSGKRKSGKDFVTEALQSRLGADV-----CAVLRLSGPLKEQYAQEHGLNFQRLL 63
RL++L +G +GKD+ + S L A + +S K +YA G + RLL
Sbjct: 766 RLIILVTGDSCAGKDYCADIWVSALLAYNHKGLTARAVSISDATKREYATATGADLNRLL 825
Query: 64 DTSTYKEAFRKDMIRWGEEKRQADPGF----FCRKIVEGISQPIWLVSDTRRVSDIQWFR 119
YKE R + + +++ + P F + + L++ R + + F
Sbjct: 826 SDRAYKEQHRPALTAFFQDQVRHRPRLPEEHFLNVVDSAADVDVLLITGMRDEAPVATFS 885
Query: 120 EAYGA-VTQTVRVVALEQSRQQRGWV 144
VRV A E+ R+ RG
Sbjct: 886 HLVPDARLLEVRVQAGEEMRRARGGC 911
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
sp|Q9D1G2|PMVK_MOUSE Phosphomevalonate kinase (PMKase) >gi|... 329 6e-89
ref|NP_001008353.1| phosphomevalonate kinase [Rattus norveg... 329 7e-89
dbj|BAE40294.1| unnamed protein product [Mus musculus] >gi|... 328 1e-88
ref|XP_001497725.1| PREDICTED: similar to phosphomevalonate... 326 5e-88
ref|NP_081060.1| phosphomevalonate kinase [Mus musculus] >g... 326 5e-88
ref|NP_001039616.1| phosphomevalonate kinase [Bos taurus] >... 324 2e-87
gb|AAV38778.1| phosphomevalonate kinase [synthetic construc... 324 2e-87
gb|AAV38779.1| phosphomevalonate kinase [Homo sapiens] >gi|... 324 2e-87
gb|AAQ02411.1| phosphomevalonate kinase [synthetic construct] 323 3e-87
ref|NP_006547.1| phosphomevalonate kinase [Homo sapiens] >g... 323 3e-87
ref|XP_001114509.1| PREDICTED: phosphomevalonate kinase [Ma... 323 3e-87
gb|AAX37126.1| phosphomevalonate kinase [synthetic construct] 323 6e-87
ref|XP_513842.2| PREDICTED: phosphomevalonate kinase [Pan t... 321 1e-86
gb|EDL15190.1| phosphomevalonate kinase, isoform CRA_a [Mus... 320 4e-86
ref|XP_855082.1| PREDICTED: similar to Phosphomevalonate ki... 309 7e-83
ref|XP_001373420.1| PREDICTED: similar to Phosphomevalonate... 305 1e-81
dbj|BAB28875.1| unnamed protein product [Mus musculus] >gi|... 274 2e-72
ref|NP_001077048.1| phosphomevalonate kinase [Danio rerio] ... 272 9e-72
ref|XP_689489.2| PREDICTED: similar to Phosphomevalonate ki... 271 1e-71
gb|AAC60791.1| phosphomevalonate kinase [Homo sapiens] 263 6e-69
dbj|BAF62110.1| phosphomevalonate kinase [Bombyx mori] 254 2e-66
ref|XP_001120920.1| PREDICTED: similar to Phosphomevalonate... 253 4e-66
ref|XP_001748282.1| predicted protein [Monosiga brevicollis... 252 1e-65
ref|NP_001040145.1| phosphomevalonate kinase [Bombyx mori] ... 249 7e-65
ref|XP_310779.4| AGAP000338-PA [Anopheles gambiae str. PEST... 249 8e-65
ref|XP_974268.1| PREDICTED: similar to Phosphomevalonate ki... 241 1e-62
ref|XP_001604440.1| PREDICTED: similar to phosphomevalonate... 241 2e-62
gb|EDM00620.1| phosphomevalonate kinase, isoform CRA_a [Rat... 239 8e-62
ref|XP_001635081.1| predicted protein [Nematostella vectens... 238 2e-61
gb|AAW26333.1| SJCHGC02790 protein [Schistosoma japonicum] 231 2e-59
ref|XP_001270504.1| phosphoribosyl transferase domain prote... 227 4e-58
ref|XP_001357257.1| GA10206-PA [Drosophila pseudoobscura] >... 226 6e-58
ref|XP_001664006.1| phosphomevalonate kinase, putative [Aed... 225 1e-57
ref|NP_872133.1| F32D8.13 [Caenorhabditis elegans] >gi|2831... 222 1e-56
gb|ABF18214.1| phosphomevalonate kinase [Aedes aegypti] 221 2e-56
sp|Q29081|PMVK_PIG Phosphomevalonate kinase (PMKase) 218 1e-55
ref|XP_001673885.1| Hypothetical protein CBG09742 [Caenorha... 217 4e-55
ref|NP_001089752.1| hypothetical protein LOC734816 [Xenopus... 216 9e-55
ref|NP_609992.1| CG10268 CG10268-PA [Drosophila melanogaste... 214 2e-54
gb|AAM51057.1| SD12705p [Drosophila melanogaster] 214 2e-54
ref|XP_001866014.1| phosphomevalonate kinase [Culex pipiens... 214 3e-54
ref|XP_001801140.1| hypothetical protein SNOG_10882 [Phaeos... 206 8e-52
gb|AAH28659.1| Pmvk protein [Mus musculus] 204 2e-51
ref|XP_001818778.1| hypothetical protein [Aspergillus oryza... 203 4e-51
gb|EDM00621.1| phosphomevalonate kinase, isoform CRA_b [Rat... 202 8e-51
ref|XP_001211374.1| conserved hypothetical protein [Aspergi... 198 2e-49
ref|XP_001224477.1| hypothetical protein CHGG_06821 [Chaeto... 196 9e-49
ref|XP_359731.1| hypothetical protein MGG_05046 [Magnaporth... 185 2e-45
ref|XP_383779.1| hypothetical protein FG03603.1 [Gibberella... 181 2e-44
ref|XP_001907258.1| unnamed protein product [Podospora anse... 181 2e-44
gb|EDU43013.1| 6-hydroxy-D-nicotine oxidase [Pyrenophora tr... 176 9e-43
gb|AAC37331.1| phosphomevalonate kinase 175 2e-42
ref|XP_001598716.1| hypothetical protein SS1G_00805 [Sclero... 170 6e-41
ref|XP_001559442.1| hypothetical protein BC1G_02106 [Botryo... 164 2e-39
emb|CAF95044.1| unnamed protein product [Tetraodon nigrovir... 164 4e-39
ref|YP_278526.1| hypothetical protein MS53_0403 [Mycoplasma... 145 1e-33
gb|AAP06404.1| similar to GenBank Accession Number AP001507... 139 8e-32
gb|EDM00623.1| phosphomevalonate kinase, isoform CRA_d [Rat... 139 2e-31
ref|YP_189074.1| hypothetical protein SERP1509 [Staphylococ... 134 3e-30
gb|ABX64470.1| putative deoxynucleotide monophosphate kinas... 134 3e-30
ref|XP_001892529.1| phosphomevalonate kinase [Brugia malayi... 121 2e-26
ref|NP_041167.1| ORF77 [Ictalurid herpesvirus 1] >gi|138108... 112 1e-23
ref|NP_047943.1| gp52 [Streptomyces phage phiC31] >gi|39474... 111 3e-23
gb|ABA40789.1| SJCHGC02791 protein [Schistosoma japonicum] 56 1e-06
Sequences not found previously or not previously below threshold:
ref|NP_813711.1| gp52 [Streptomyces phage phiBT1] >gi|29243... 92 2e-17
ref|YP_001212697.1| adenylate kinase and related kinases [P... 80 5e-14
ref|NP_600975.1| hypothetical protein NCgl1698 [Corynebacte... 75 2e-12
ref|ZP_02327437.1| adenylate kinase and related kinases [Pa... 74 7e-12
ref|YP_001642759.1| adenylate kinase-like protein [Bacillus... 72 2e-11
ref|NP_041166.1| ORF76 [Ictalurid herpesvirus 1] >gi|138107... 71 3e-11
ref|ZP_02443545.1| hypothetical protein ANACOL_02862 [Anaer... 66 2e-09
ref|ZP_02357920.1| hypothetical protein BoklE_20810 [Burkho... 62 2e-08
ref|NP_899571.1| dNMP kinase [Vibrio phage KVP40] >gi|34333... 61 4e-08
ref|ZP_01894233.1| deoxynucleotide monophosphate kinase, pu... 61 4e-08
ref|ZP_01643088.1| hypothetical protein SmalDRAFT_0847 [Ste... 59 2e-07
ref|YP_142866.1| deoxynucleotide monophosphate kinase [Acan... 58 3e-07
ref|YP_001671779.1| ATP-binding protein [Enterobacteria pha... 56 1e-06
ref|NP_861849.1| gp1 dNMP kinase [Enterobacteria phage RB69... 52 1e-05
gb|EEH97608.1| predicted protein [Clostridium sp. 7_2_43FAA] 52 2e-05
ref|NP_932488.1| dNMP kinase [Aeromonas phage 44RR2.8t] >gi... 51 4e-05
ref|YP_276424.1| hypothetical protein PSPPH_4306 [Pseudomon... 50 8e-05
dbj|BAF32837.1| hypothetical protein [Pseudomonas syringae ... 49 2e-04
ref|YP_001595273.1| gp1 dNMP kinase [Enterobacteria phage J... 49 2e-04
dbj|BAG13639.1| conserved hypothetical protein [uncultured ... 48 4e-04
ref|ZP_03981046.1| conserved hypothetical protein [Enteroco... 47 6e-04
ref|NP_944963.1| Putative deoxynucleotide monophosphate kin... 47 7e-04
ref|YP_920099.1| dephospho-CoA kinase [Thermofilum pendens ... 47 0.001
ref|ZP_00603651.1| hypothetical protein EfaeDRAFT_1703 [Ent... 46 0.001
ref|YP_982503.1| hypothetical protein Pnap_2274 [Polaromona... 46 0.001
ref|ZP_02468156.1| hypothetical protein Bpse38_32660 [Burkh... 45 0.002
emb|CAI64255.1| hypothetical protein [uncultured archaeon] 45 0.002
ref|XP_001517271.1| PREDICTED: similar to phosphomevalonate... 45 0.003
ref|YP_001533397.1| hypothetical protein Dshi_2059 [Dinoros... 45 0.003
ref|YP_184605.1| hypothetical protein TK2192 [Thermococcus ... 45 0.004
gb|ACP31065.1| gp1 dNMP kinase [Enterobacteria phage RB51] 44 0.004
ref|YP_001595438.1| phage protein [Enterobacteria phage phi... 44 0.007
ref|NP_342513.1| Adenylate kinase related protein (adkA-lik... 44 0.008
ref|YP_674901.1| Xanthosine triphosphate pyrophosphatase-li... 44 0.008
ref|YP_552007.1| type II secretion system protein E [Polaro... 43 0.011
ref|XP_001750301.1| predicted protein [Monosiga brevicollis... 43 0.011
ref|YP_656358.1| gp1 dNMP kinase [Aeromonas phage 25] >gi|1... 43 0.013
ref|YP_966498.1| hypothetical protein Dvul_1051 [Desulfovib... 43 0.013
pdb|3H0K|A Chain A, Crystal Structure Of An Adenylated Kina... 43 0.014
ref|ZP_01291743.1| conserved hypothetical protein [delta pr... 42 0.019
ref|ZP_01290772.1| conserved hypothetical protein [delta pr... 42 0.019
ref|XP_385614.1| hypothetical protein FG05438.1 [Gibberella... 42 0.020
ref|YP_552195.1| type II secretion system protein E [Polaro... 42 0.027
ref|NP_049752.1| gp1 dNMP kinase [Enterobacteria phage T4] ... 42 0.027
ref|YP_803086.1| dNMP kinase [Enterobacteria phage RB32] >g... 42 0.028
pdb|1DEK|A Chain A, Deoxynucleoside Monophosphate Kinase Co... 42 0.029
ref|YP_001186391.1| bifunctional sulfate adenylyltransferas... 42 0.030
ref|YP_024737.1| hypothetical protein PaP2_gp09 [Pseudomona... 42 0.030
ref|ZP_02427632.1| hypothetical protein CLORAM_01019 [Clost... 42 0.031
ref|YP_001154185.1| adenylate kinase, conjectural [Pyrobacu... 42 0.033
ref|YP_001218811.1| hypothetical protein PP119X_gp09 [Pseud... 41 0.034
gb|ACP30788.1| gp1 dNMP kinase [Enterobacteria phage RB14] 41 0.036
ref|YP_685425.1| hypothetical protein RCIX710 [uncultured m... 41 0.041
ref|YP_576129.1| hypothetical protein Nham_0791 [Nitrobacte... 41 0.042
ref|YP_001630497.1| cmk [Bordetella petrii DSM 12804] >gi|1... 41 0.043
ref|YP_268529.1| ATP-dependent peptidase, M41 family [Colwe... 41 0.044
ref|YP_548624.1| bifunctional 3-phosphoshikimate 1-carboxyv... 41 0.055
ref|YP_183747.1| hypothetical protein TK1334 [Thermococcus ... 41 0.057
ref|NP_578095.1| hypothetical protein PF0366 [Pyrococcus fu... 40 0.060
ref|ZP_03960517.1| dephospho-CoA kinase [Lactobacillus vagi... 40 0.060
ref|YP_430405.1| twitching motility protein [Moorella therm... 40 0.064
ref|ZP_02078982.1| hypothetical protein CLOLEP_00419 [Clost... 40 0.069
ref|YP_001615111.1| twitching motility protein [Sorangium c... 40 0.077
ref|ZP_02085402.1| hypothetical protein CLOBOL_02938 [Clost... 40 0.078
ref|NP_229188.1| dephospho-CoA kinase [Thermotoga maritima ... 40 0.080
ref|NP_744116.1| deoxynucleotide monophosphate kinase, puta... 40 0.084
ref|YP_001739469.1| dephospho-CoA kinase [Thermotoga sp. RQ... 40 0.088
ref|YP_001244985.1| dephospho-CoA kinase [Thermotoga petrop... 40 0.098
ref|ZP_01666284.1| twitching motility protein [Thermosinus ... 39 0.15
pdb|2GRJ|A Chain A, Crystal Structure Of Dephospho-Coa Kina... 39 0.17
ref|ZP_01079181.1| PilT1 protein-like [Synechococcus sp. RS... 39 0.18
ref|ZP_00533639.1| conserved hypothetical protein [Chlorobi... 39 0.18
sp|O28876|Y1395_ARCFU UPF0200/UPF0201 protein AF_1395 >gi|2... 39 0.19
ref|NP_069288.1| hypothetical protein AF0452 [Archaeoglobus... 39 0.19
emb|CAL54296.1| unnamed protein product [Ostreococcus tauri] 39 0.20
ref|YP_392016.1| twitching motility protein [Thiomicrospira... 39 0.20
ref|NP_070224.2| hypothetical protein AF1395 [Archaeoglobus... 39 0.20
ref|ZP_03916746.1| PilB type IV pilus assembly protein [Ana... 39 0.20
ref|YP_931152.1| adenylate kinase, conjectural [Pyrobaculum... 38 0.23
ref|YP_001583114.1| dephospho-CoA kinase, CoaE [Nitrosopumi... 38 0.23
ref|ZP_01576064.1| twitching motility protein [Clostridium ... 38 0.23
ref|YP_001736520.1| Dephospho-CoA kinase [Candidatus Korarc... 38 0.24
ref|NP_376284.1| cytidylate kinase [Sulfolobus tokodaii str... 38 0.24
ref|NP_248402.1| alignment in /usr/local/projects/ARG/Inter... 38 0.27
ref|NP_281051.1| hypothetical protein VNG2452C [Halobacteri... 38 0.28
ref|ZP_01875920.1| twitching mobility protein PilT [Lentisp... 38 0.28
ref|YP_475374.1| twitching motility protein [Synechococcus ... 38 0.28
gb|AAT01712.1| polyprotein [Foot-and-mouth disease virus A] 38 0.28
gb|AAT01724.1| polyprotein [Foot-and-mouth disease virus A] 38 0.28
gb|AAT01732.1| polyprotein [Foot-and-mouth disease virus A] 38 0.28
gb|AAM44304.1|AF511039_1 polypeptide [Foot-and-mouth diseas... 38 0.28
ref|ZP_01471556.1| hypothetical protein RS9916_37627 [Synec... 38 0.29
ref|NP_127207.1| hypothetical protein PAB1012 [Pyrococcus a... 38 0.30
ref|ZP_00965462.1| COG2895: GTPases - Sulfate adenylate tra... 38 0.32
ref|YP_239174.1| gp1 dNMP kinase [Enterobacteria phage RB43... 38 0.33
ref|NP_396018.1| hypothetical protein Atu5082 [Agrobacteriu... 38 0.33
ref|YP_001325008.1| hypothetical protein Maeo_0813 [Methano... 38 0.34
ref|NP_680912.1| twitching motility protein [Thermosynechoc... 38 0.34
ref|YP_619655.1| Guanylate kinase [Lactobacillus delbruecki... 38 0.38
ref|YP_001350350.1| ATP sulfurylase GTP-binding subunit/APS... 38 0.38
ref|YP_401087.1| twitching motility protein [Synechococcus ... 38 0.40
ref|ZP_03998576.1| dephospho-CoA kinase [Halogeometricum bo... 38 0.40
ref|YP_172733.1| twitching motility protein PilT [Synechoco... 38 0.41
ref|NP_952543.1| twitching motility protein PilT [Geobacter... 38 0.41
ref|YP_729259.1| twitching motility protein [Synechococcus ... 38 0.46
ref|YP_380356.1| twitching motility protein [Synechococcus ... 38 0.47
ref|ZP_01363891.1| hypothetical protein PaerPA_01000994 [Ps... 38 0.48
ref|YP_137558.1| adenylate kinase [Haloarcula marismortui A... 38 0.48
ref|YP_570089.1| ABC transporter related [Rhodopseudomonas ... 37 0.49
ref|ZP_00971103.1| COG2895: GTPases - Sulfate adenylate tra... 37 0.53
ref|NP_253132.1| bifunctional sulfate adenylyltransferase s... 37 0.53
ref|YP_001223743.1| Tfp pilus assembly protein, pilus retra... 37 0.53
ref|ZP_02037068.1| hypothetical protein BACCAP_02681 [Bacte... 37 0.55
ref|NP_951301.1| malonyl Coa-acyl carrier protein transacyl... 37 0.56
ref|NP_893852.1| homologous to PilT1 protein [Prochlorococc... 37 0.57
ref|NP_566276.1| guanylate kinase, putative [Arabidopsis th... 37 0.59
ref|NP_757612.1| hypothetical protein MYPE2250 [Mycoplasma ... 37 0.59
ref|YP_181647.1| twitching mobility protein [Dehalococcoide... 37 0.60
gb|AAQ55600.1| polypeptide [Foot-and-mouth disease virus O] 37 0.60
ref|NP_108493.1| hypothetical protein mlr8387 [Mesorhizobiu... 37 0.61
ref|ZP_02203200.1| twitching motility protein [Dehalococcoi... 37 0.62
ref|ZP_02015288.1| dephospho-CoA kinase [Halorubrum lacuspr... 37 0.65
emb|CAF21826.1| recombinase A [Lactococcus lactis subsp. la... 37 0.67
ref|NP_275577.1| UMP/CMP kinase related protein [Methanothe... 37 0.68
ref|YP_384096.1| AAA ATPase, central region [Geobacter meta... 37 0.70
ref|ZP_00144210.1| RecA protein [Fusobacterium nucleatum su... 37 0.71
ref|ZP_01708684.1| hypothetical protein Faci_03001313 [Ferr... 37 0.73
gb|ABD75780.1| hypothetical protein [uncultured bacterium] 37 0.74
ref|ZP_02172719.1| twitching motility protein [Anaeromyxoba... 37 0.75
ref|ZP_02321974.1| twitching motility protein [Anaeromyxoba... 37 0.75
ref|NP_613685.1| Dephospho-CoA kinase [Methanopyrus kandler... 37 0.76
ref|YP_003883.1| hypothetical protein T1p62 [Enterobacteria... 37 0.76
ref|ZP_01201433.1| guanylate kinase [Flavobacteria bacteriu... 37 0.80
ref|YP_001277904.1| Guanylate kinase [Roseiflexus sp. RS-1]... 37 0.81
ref|YP_277500.1| hypothetical protein T1p62 [Enterobacteria... 37 0.82
ref|ZP_02944852.1| protein of unknown function DUF344 [Micr... 37 0.86
gb|AAA25216.1| recA 37 0.87
ref|YP_318208.1| hypothetical protein Nwi_1595 [Nitrobacter... 37 0.89
ref|YP_462275.1| general secretion pathway protein E [Syntr... 37 0.91
ref|YP_522072.1| ATPase [Rhodoferax ferrireducens T118] >gi... 37 0.91
ref|YP_001377865.1| twitching motility protein [Anaeromyxob... 37 0.91
ref|YP_478351.1| twitching motility protein [Synechococcus ... 37 0.93
ref|YP_463836.1| twitching motility protein [Anaeromyxobact... 37 0.93
ref|YP_808429.1| recombinase A [Lactococcus lactis subsp. c... 37 0.97
ref|YP_001453786.1| hypothetical protein CKO_02227 [Citroba... 37 0.99
ref|ZP_02927889.1| hypothetical protein VspiD_14605 [Verruc... 37 0.99
sp|P0C2U5|RECA_LACLC Protein recA (Recombinase A) 37 1.0
ref|ZP_02166259.1| hypothetical protein HPDFL43_05395 [Hoef... 37 1.0
ref|ZP_02951629.1| conserved hypothetical protein [Clostrid... 37 1.0
ref|NP_266510.1| recombinase A [Lactococcus lactis subsp. l... 37 1.1
ref|ZP_02423367.1| hypothetical protein EUBSIR_02226 [Eubac... 37 1.1
gb|AAF30313.1|AC018907_13 putative guanylate kinase [Arabid... 36 1.1
ref|ZP_03990813.1| MRP-family nucleotide-binding protein [O... 36 1.1
ref|ZP_02942481.1| conserved hypothetical protein [Cyanothe... 36 1.1
ref|YP_566773.1| hypothetical protein Mbur_2153 [Methanococ... 36 1.1
ref|YP_001898086.1| molybdopterin-guanine dinucleotide bios... 36 1.1
ref|ZP_02272686.1| recombinase A [Fusobacterium nucleatum s... 36 1.1
ref|ZP_03844254.1| possible guanylate kinase [Lactobacillus... 36 1.2
ref|ZP_01871032.1| twitching motility protein [Caminibacter... 36 1.2
ref|ZP_02007492.1| molybdopterin-guanine dinucleotide biosy... 36 1.2
gb|EEJ83168.1| adenylylsulfate kinase ApsK [Kytococcus sede... 36 1.2
ref|YP_023587.1| hypothetical protein PTO0809 [Picrophilus ... 36 1.2
ref|YP_001012555.1| Dephospho-CoA kinase, CoaE [Hyperthermu... 36 1.2
ref|ZP_02544619.1| twitching motility protein [candidate di... 36 1.2
ref|YP_532190.1| ABC transporter related [Rhodopseudomonas ... 36 1.2
ref|ZP_02848947.1| methylmalonyl-CoA mutase, large subunit ... 36 1.2
gb|AAM93532.1| RecA protein [Rickettsia typhi] 36 1.3
ref|YP_486100.1| ABC transporter related [Rhodopseudomonas ... 36 1.3
ref|YP_001834244.1| protein of unknown function DUF344 [Bei... 36 1.3
ref|YP_922333.1| twitching motility protein [Nocardioides s... 36 1.3
ref|YP_995725.1| RNA polymerase, sigma 28 subunit, FliA/Whi... 36 1.3
ref|YP_288815.1| putative ATP-binding protein [Thermobifida... 36 1.4
gb|ABA55990.1| sulfate adenylate transferase subunit 1 [Sin... 36 1.4
ref|ZP_02374287.1| hypothetical protein BthaT_24926 [Burkho... 36 1.4
ref|ZP_02441167.1| hypothetical protein ANACOL_00437 [Anaer... 36 1.4
ref|YP_001036227.1| Tfp pilus assembly protein, pilus retra... 36 1.4
ref|YP_872309.1| twitching motility protein [Acidothermus c... 36 1.4
gb|AAL38651.1| GspE [Burkholderia cenocepacia] 36 1.4
ref|YP_864079.1| protein of unknown function DUF344 [Magnet... 36 1.5
ref|YP_067686.1| recombinase A [Rickettsia typhi str. Wilmi... 36 1.5
ref|ZP_02560823.1| hypothetical protein Sente_11446 [Salmon... 36 1.5
ref|XP_001209684.1| conserved hypothetical protein [Aspergi... 36 1.5
ref|ZP_02845866.1| uridine kinase [Paenibacillus sp. JDR-2]... 36 1.5
ref|YP_643943.1| twitching motility protein [Rubrobacter xy... 36 1.6
ref|XP_532101.2| PREDICTED: similar to Antigen peptide tran... 36 1.6
ref|XP_001013980.1| hypothetical protein TTHERM_00398050 [T... 36 1.6
emb|CAH63454.1| transporter 1, ATP-binding cassette, sub-fa... 36 1.6
ref|YP_384353.1| Pilus retraction protein PilT [Geobacter m... 36 1.6
ref|YP_813708.1| Gmk, Guanylate kinase [Lactobacillus delbr... 36 1.6
ref|NP_808507.1| tenascin N [Mus musculus] >gi|34395869|sp|... 36 1.6
ref|YP_001532986.1| recA protein [Dinoroseobacter shibae DF... 36 1.6
ref|YP_001467881.1| dNMP kinase [Thermus phage P23-45] >gi|... 36 1.6
ref|ZP_02078026.1| hypothetical protein EUBDOL_01834 [Eubac... 36 1.7
gb|ABG54264.1| type IV pili twitching motility protein [Mic... 36 1.7
ref|YP_743229.1| general secretory pathway protein E [Alkal... 36 1.7
ref|NP_388476.1| hypothetical protein BSU05950 [Bacillus su... 36 1.7
ref|XP_001312533.1| hypothetical protein TVAG_427670 [Trich... 36 1.8
ref|YP_827486.1| Adenylosuccinate synthase [Solibacter usit... 36 1.8
sp|Q8RFY0|RECA_FUSNN Protein recA (Recombinase A) 36 1.8
ref|NP_603444.1| recombinase A [Fusobacterium nucleatum sub... 36 1.8
ref|ZP_01549379.1| hypothetical protein SIAM614_24952 [Stap... 36 1.8
ref|YP_001229009.1| twitching motility protein [Geobacter u... 36 1.8
ref|YP_145040.1| pili retraction protein PilT [Thermus ther... 36 1.8
gb|EDL39344.1| tenascin N, isoform CRA_b [Mus musculus] 36 1.8
ref|ZP_02918965.1| hypothetical protein BIFDEN_02285 [Bifid... 36 1.8
ref|ZP_00943122.1| Molybdopterin-guanine dinucleotide biosy... 35 1.9
ref|YP_001211696.1| tfp pilus assembly protein, pilus retra... 35 1.9
ref|ZP_00999038.1| recombinase A [Oceanicola batsensis HTCC... 35 2.0
ref|ZP_01754885.1| hypothetical protein RSK20926_22364 [Ros... 35 2.0
ref|NP_852941.1| Cmk [Mycoplasma gallisepticum R] >gi|59798... 35 2.1
ref|YP_001023420.1| type II secretory pathway ATPase PulE/T... 35 2.1
ref|YP_161738.1| adenylylsulfate kinase [Zymomonas mobilis ... 35 2.1
gb|EEJ89030.1| conserved hypothetical nucleotide-binding pr... 35 2.1
ref|YP_001298947.1| guanylate kinase [Bacteroides vulgatus ... 35 2.1
ref|ZP_01217518.1| negative regulator of genetic competence... 35 2.2
ref|YP_560984.1| Putative general secretion pathway protein... 35 2.2
ref|YP_001897548.1| general secretory pathway protein E [Bu... 35 2.2
ref|YP_001793280.1| protein of unknown function DUF344 [Lep... 35 2.2
ref|NP_142483.1| hypothetical protein PH0515 [Pyrococcus ho... 35 2.2
ref|NP_001049956.1| Os03g0320900 [Oryza sativa (japonica cu... 35 2.2
ref|YP_771946.1| general secretory pathway protein E [Burkh... 35 2.4
ref|YP_001214267.1| twitching motility protein [Dehalococco... 35 2.4
ref|ZP_02907963.1| general secretory pathway protein E [Bur... 35 2.4
dbj|BAB18789.1| GspE [Burkholderia cepacia] 35 2.4
gb|AAG18590.1|AF297458_1 pilin biogenesis protein PilT [Pse... 35 2.4
ref|YP_001806779.1| general secretory pathway protein E [Bu... 35 2.4
ref|ZP_02890095.1| general secretory pathway protein E [Bur... 35 2.4
ref|YP_619898.1| Type II secretion system gspE [Burkholderi... 35 2.4
ref|YP_307929.1| twitching mobility protein [Dehalococcoide... 35 2.4
ref|YP_001763382.1| general secretory pathway protein E [Bu... 35 2.4
ref|ZP_00419110.1| conserved hypothetical protein [Azotobac... 35 2.5
ref|ZP_01062072.1| guanylate kinase [Flavobacterium sp. MED... 35 2.5
ref|ZP_00981211.1| COG2804: Type II secretory pathway, ATPa... 35 2.6
emb|CAJ71054.1| conserved hypothetical protein [Candidatus ... 35 2.6
ref|YP_001794069.1| adenylate kinase, conjectural [Thermopr... 35 2.6
ref|NP_969445.1| uridine kinase [Bdellovibrio bacteriovorus... 35 2.6
>sp|Q9D1G2|PMVK_MOUSE Phosphomevalonate kinase (PMKase)
gb|EDL15192.1| phosphomevalonate kinase, isoform CRA_c [Mus musculus]
Length = 192
Score = 329 bits (845), Expect = 6e-89, Method: Composition-based stats.
Identities = 160/192 (83%), Positives = 180/192 (93%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE +R+DMI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+E
Sbjct: 61 RLLDASTYKETYRRDMICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAV QTVRVVA EQSRQQRGWVFTPGVDDAESECGLDNFG+FDWVIENHG EQ LE+Q
Sbjct: 121 AYGAVIQTVRVVASEQSRQQRGWVFTPGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LE+L+ FI+++L
Sbjct: 181 LEHLLGFIQAKL 192
>ref|NP_001008353.1| phosphomevalonate kinase [Rattus norvegicus]
gb|AAH86349.1| Phosphomevalonate kinase [Rattus norvegicus]
gb|EDM00622.1| phosphomevalonate kinase, isoform CRA_c [Rattus norvegicus]
Length = 194
Score = 329 bits (844), Expect = 7e-89, Method: Composition-based stats.
Identities = 164/192 (85%), Positives = 181/192 (94%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE LQSRLG ++CAVLRLSGPLKEQYA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLQSRLGGNICAVLRLSGPLKEQYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
+LLD STYKE +R+DMI WGEEKRQADPGFFCRKIVEG+SQPIWLVSDTRR+SDIQWF+E
Sbjct: 61 KLLDASTYKETYRRDMICWGEEKRQADPGFFCRKIVEGVSQPIWLVSDTRRMSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVA EQSRQQRGWVFT GVDDAESECGLD+FGDFDWVIENHG EQ LE+Q
Sbjct: 121 AYGALTQTVRVVASEQSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LENL+EFI ++L
Sbjct: 181 LENLLEFIHAKL 192
>dbj|BAE40294.1| unnamed protein product [Mus musculus]
dbj|BAE29599.1| unnamed protein product [Mus musculus]
Length = 192
Score = 328 bits (842), Expect = 1e-88, Method: Composition-based stats.
Identities = 160/192 (83%), Positives = 179/192 (93%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE +R DMI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+E
Sbjct: 61 RLLDASTYKETYRGDMICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAV QTVRVVA EQSRQQRGWVFTPGVDDAESECGLDNFG+FDWVIENHG EQ LE+Q
Sbjct: 121 AYGAVIQTVRVVASEQSRQQRGWVFTPGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LE+L+ FI+++L
Sbjct: 181 LEHLLGFIQAKL 192
>ref|XP_001497725.1| PREDICTED: similar to phosphomevalonate kinase [Equus caballus]
Length = 192
Score = 326 bits (837), Expect = 5e-88, Method: Composition-based stats.
Identities = 178/192 (92%), Positives = 186/192 (96%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEA QSRLGADVCA+LRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEAPQSRLGADVCAILRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKEA+R+DMIRWGEEKRQADPGFFCRKIVEG+SQP+WLVSDTRRVSDIQWF+E
Sbjct: 61 RLLDASTYKEAYRRDMIRWGEEKRQADPGFFCRKIVEGVSQPVWLVSDTRRVSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
YGA+TQT+RVVALEQSRQQRGWVFTPGVDDAESECGLDNFG FDWVIENHG EQRLEEQ
Sbjct: 121 TYGAMTQTIRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGGFDWVIENHGDEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFI SRL
Sbjct: 181 LENLIEFIHSRL 192
>ref|NP_081060.1| phosphomevalonate kinase [Mus musculus]
dbj|BAB22886.1| unnamed protein product [Mus musculus]
Length = 192
Score = 326 bits (837), Expect = 5e-88, Method: Composition-based stats.
Identities = 159/192 (82%), Positives = 179/192 (93%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA+EHGL+FQ
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE +R+DMI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+E
Sbjct: 61 RLLDASTYKETYRRDMICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAV QTVRVVA EQSRQQRGWVFT GVDDAESECGLDNFG+FDWVIENHG EQ LE+Q
Sbjct: 121 AYGAVIQTVRVVASEQSRQQRGWVFTLGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQ 180
Query: 181 LENLIEFIRSRL 192
LE+L+ FI+++L
Sbjct: 181 LEHLLGFIQAKL 192
>ref|NP_001039616.1| phosphomevalonate kinase [Bos taurus]
sp|Q2KIU2|PMVK_BOVIN Phosphomevalonate kinase (PMKase)
gb|AAI12510.1| Phosphomevalonate kinase [Bos taurus]
Length = 192
Score = 324 bits (832), Expect = 2e-87, Method: Composition-based stats.
Identities = 173/192 (90%), Positives = 182/192 (94%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGG P LVLLFSGKRKSGKDFVTEALQSRLGADVCA+LRLSGPLKEQYAQEHGL+FQ
Sbjct: 1 MAPLGGVPGLVLLFSGKRKSGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RL+D STYKEA+R DMIRWGEEKRQADPGFFCRKIVEG+ QP+WLVSDTRRVSDIQWF+E
Sbjct: 61 RLMDASTYKEAYRSDMIRWGEEKRQADPGFFCRKIVEGVCQPVWLVSDTRRVSDIQWFQE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVA E+SRQQRGWVFTPGVDDAESECGLDNF FDWVIENHG EQ LEEQ
Sbjct: 121 AYGAVTQTVRVVATEESRQQRGWVFTPGVDDAESECGLDNFRTFDWVIENHGDEQHLEEQ 180
Query: 181 LENLIEFIRSRL 192
LE+LIEFIRSRL
Sbjct: 181 LEHLIEFIRSRL 192
>gb|AAV38778.1| phosphomevalonate kinase [synthetic construct]
gb|AAX42912.1| phosphomevalonate kinase [synthetic construct]
gb|AAX42913.1| phosphomevalonate kinase [synthetic construct]
gb|AAX42914.1| phosphomevalonate kinase [synthetic construct]
Length = 193
Score = 324 bits (832), Expect = 2e-87, Method: Composition-based stats.
Identities = 191/192 (99%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAMTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>gb|AAV38779.1| phosphomevalonate kinase [Homo sapiens]
gb|AAX41326.1| phosphomevalonate kinase [synthetic construct]
gb|AAX41327.1| phosphomevalonate kinase [synthetic construct]
gb|AAX41328.1| phosphomevalonate kinase [synthetic construct]
Length = 192
Score = 324 bits (831), Expect = 2e-87, Method: Composition-based stats.
Identities = 191/192 (99%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAMTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>gb|AAQ02411.1| phosphomevalonate kinase [synthetic construct]
Length = 193
Score = 323 bits (830), Expect = 3e-87, Method: Composition-based stats.
Identities = 192/192 (100%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>ref|NP_006547.1| phosphomevalonate kinase [Homo sapiens]
sp|Q15126|PMVK_HUMAN Phosphomevalonate kinase (PMKase)
gb|AAC37593.1| phosphomevalonate kinase
gb|AAH06089.1| Phosphomevalonate kinase [Homo sapiens]
gb|AAH07694.1| Phosphomevalonate kinase [Homo sapiens]
emb|CAG46795.1| PMVK [Homo sapiens]
emb|CAI13237.1| phosphomevalonate kinase [Homo sapiens]
gb|EAW53177.1| phosphomevalonate kinase, isoform CRA_a [Homo sapiens]
gb|EAW53178.1| phosphomevalonate kinase, isoform CRA_a [Homo sapiens]
Length = 192
Score = 323 bits (830), Expect = 3e-87, Method: Composition-based stats.
Identities = 192/192 (100%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>ref|XP_001114509.1| PREDICTED: phosphomevalonate kinase [Macaca mulatta]
Length = 192
Score = 323 bits (829), Expect = 3e-87, Method: Composition-based stats.
Identities = 187/192 (97%), Positives = 188/192 (97%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPL GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLAGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDASTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFG FDWVIENHG EQRLEEQ
Sbjct: 121 AYGAMTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGGFDWVIENHGDEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>gb|AAX37126.1| phosphomevalonate kinase [synthetic construct]
Length = 193
Score = 323 bits (828), Expect = 6e-87, Method: Composition-based stats.
Identities = 192/192 (100%), Positives = 192/192 (100%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>ref|XP_513842.2| PREDICTED: phosphomevalonate kinase [Pan troglodytes]
Length = 192
Score = 321 bits (824), Expect = 1e-86, Method: Composition-based stats.
Identities = 189/192 (98%), Positives = 189/192 (98%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLGGAPRLVLLFSGKRKSGKDFVT ALQS LGADVCAVLRLSGPLKEQYAQEHGLNFQ
Sbjct: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTXALQSXLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQ LEEQ
Sbjct: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQHLEEQ 180
Query: 181 LENLIEFIRSRL 192
LENLIEFIRSRL
Sbjct: 181 LENLIEFIRSRL 192
>gb|EDL15190.1| phosphomevalonate kinase, isoform CRA_a [Mus musculus]
Length = 206
Score = 320 bits (820), Expect = 4e-86, Method: Composition-based stats.
Identities = 161/206 (78%), Positives = 180/206 (87%), Gaps = 14/206 (6%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYA-------- 52
MAPLG +PRLVLLFSGKRKSGKDFVTE L+SRLG ++CA+LRLSGPLKE+YA
Sbjct: 1 MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREGWWDCV 60
Query: 53 ------QEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLV 106
QEHGL+FQRLLD STYKE +R+DMI WGE+KRQADPGFFCRKIVEG+SQPIWLV
Sbjct: 61 IDGLALQEHGLDFQRLLDASTYKETYRRDMICWGEQKRQADPGFFCRKIVEGVSQPIWLV 120
Query: 107 SDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDW 166
SDTRR SDIQWF+EAYGAV QTVRVVA EQSRQQRGWVFTPGVDDAESECGLDNFG+FDW
Sbjct: 121 SDTRRTSDIQWFQEAYGAVIQTVRVVASEQSRQQRGWVFTPGVDDAESECGLDNFGNFDW 180
Query: 167 VIENHGVEQRLEEQLENLIEFIRSRL 192
VIENHG EQ LE+QLE+L+ FI+++L
Sbjct: 181 VIENHGDEQCLEDQLEHLLGFIQAKL 206
>ref|XP_855082.1| PREDICTED: similar to Phosphomevalonate kinase (PMKase) [Canis
familiaris]
Length = 192
Score = 309 bits (792), Expect = 7e-83, Method: Composition-based stats.
Identities = 168/192 (87%), Positives = 178/192 (92%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAP GGAP LVLL SGKRKSGKDFV EAL+SRLGADVCAVLRLSGPLKEQYA+EH L+FQ
Sbjct: 1 MAPRGGAPCLVLLVSGKRKSGKDFVAEALRSRLGADVCAVLRLSGPLKEQYAKEHDLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD S YKEAFR+DMIRWGEEKRQADPGFFCRK+VEG+ QP+WLVSDTRRVSDIQWFRE
Sbjct: 61 RLLDASAYKEAFRRDMIRWGEEKRQADPGFFCRKVVEGVFQPVWLVSDTRRVSDIQWFRE 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
AYGA+TQTVRVVA EQSRQQRGWVFT GVDDAESECGLDNFG FDWVIENHG EQRLEEQ
Sbjct: 121 AYGALTQTVRVVASEQSRQQRGWVFTTGVDDAESECGLDNFGAFDWVIENHGDEQRLEEQ 180
Query: 181 LENLIEFIRSRL 192
LE L+ F+RSRL
Sbjct: 181 LEKLVVFVRSRL 192
>ref|XP_001373420.1| PREDICTED: similar to Phosphomevalonate kinase [Monodelphis
domestica]
Length = 204
Score = 305 bits (782), Expect = 1e-81, Method: Composition-based stats.
Identities = 149/192 (77%), Positives = 172/192 (89%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAP +PRLVLLFSGKRKSGKDFVT+ L+SRLG DVCAVLRLSGPLKEQYA+EHGL+FQ
Sbjct: 1 MAPRVDSPRLVLLFSGKRKSGKDFVTDELRSRLGTDVCAVLRLSGPLKEQYAKEHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD S+YKEAFR+DMIRWGEEKR+ADPGFFCRKIVEG+ QP+WLVSDTRR SDI WF+
Sbjct: 61 RLLDASSYKEAFRQDMIRWGEEKREADPGFFCRKIVEGVPQPVWLVSDTRRESDIHWFQA 120
Query: 121 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
++G VTQ VRVVA E+SR+QRGWVFT GVDDAESECGLD+F FDWVIENHG +++LE+Q
Sbjct: 121 SFGDVTQLVRVVASEESRRQRGWVFTAGVDDAESECGLDHFEAFDWVIENHGEDRKLEQQ 180
Query: 181 LENLIEFIRSRL 192
L L++FI S+L
Sbjct: 181 LGKLVDFIHSKL 192
>dbj|BAB28875.1| unnamed protein product [Mus musculus]
gb|EDL15191.1| phosphomevalonate kinase, isoform CRA_b [Mus musculus]
Length = 171
Score = 274 bits (702), Expect = 2e-72, Method: Composition-based stats.
Identities = 133/165 (80%), Positives = 152/165 (92%)
Query: 28 ALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQAD 87
+RLG ++CA+LRLSGPLKE+YA+EHGL+FQRLLD STYKE +R+DMI WGE+KRQAD
Sbjct: 7 IFYARLGGNICALLRLSGPLKEEYAREHGLDFQRLLDASTYKETYRRDMICWGEQKRQAD 66
Query: 88 PGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTP 147
PGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+EAYGAV QTVRVVA EQSRQQRGWVFTP
Sbjct: 67 PGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQEAYGAVIQTVRVVASEQSRQQRGWVFTP 126
Query: 148 GVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
GVDDAESECGLDNFG+FDWVIENHG EQ LE+QLE+L+ FI+++L
Sbjct: 127 GVDDAESECGLDNFGNFDWVIENHGDEQCLEDQLEHLLGFIQAKL 171
>ref|NP_001077048.1| phosphomevalonate kinase [Danio rerio]
ref|XP_689711.2| PREDICTED: similar to Phosphomevalonate kinase [Danio rerio]
gb|AAI35046.1| Zgc:162701 protein [Danio rerio]
Length = 199
Score = 272 bits (696), Expect = 9e-72, Method: Composition-based stats.
Identities = 102/185 (55%), Positives = 139/185 (75%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
P ++LLFSGKRKSGKD+VT+ +Q RL A++C +LRLS PLKEQYA++H L+++ L+ +
Sbjct: 6 PSIILLFSGKRKSGKDYVTDLIQKRLTAEICCILRLSAPLKEQYAKDHNLDYEELMGSGQ 65
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQ 127
YKE++R DMI WGE KRQ D GFFCR ++ +QP+W++SD RR+SD+QWFREA+
Sbjct: 66 YKESYRADMIHWGEMKRQEDSGFFCRLAIKHATQPVWIISDCRRMSDVQWFREAFPNKCV 125
Query: 128 TVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEF 187
VRV A EQ+R +RGW FT G+DDAESECGLD FD +I N G + LE+ L+ L+
Sbjct: 126 CVRVEASEQTRSERGWRFTSGIDDAESECGLDEGVKFDRIIRNDGSDDILEKHLDELLSS 185
Query: 188 IRSRL 192
+RS++
Sbjct: 186 VRSQV 190
>ref|XP_689489.2| PREDICTED: similar to Phosphomevalonate kinase [Danio rerio]
Length = 199
Score = 271 bits (695), Expect = 1e-71, Method: Composition-based stats.
Identities = 102/185 (55%), Positives = 139/185 (75%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
P ++LLFSGKRKSGKD+VT+ +Q RL A++C +LRLS PLKEQYA++H L+++ L+ +
Sbjct: 6 PSIILLFSGKRKSGKDYVTDLIQKRLTAEMCCILRLSAPLKEQYAKDHNLDYEELMGSGQ 65
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQ 127
YKE++R DMI WGE KRQ D GFFCR ++ +QP+W++SD RR+SD+QWFREA+
Sbjct: 66 YKESYRADMIHWGEMKRQEDSGFFCRLAIKHATQPVWIISDCRRMSDVQWFREAFPNKCV 125
Query: 128 TVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEF 187
VRV A EQ+R +RGW FT G+DDAESECGLD FD +I N G + LE+ L+ L+
Sbjct: 126 CVRVEASEQTRSERGWRFTSGIDDAESECGLDEGVKFDRIIRNDGSDDILEKHLDELLSS 185
Query: 188 IRSRL 192
+RS++
Sbjct: 186 VRSQV 190
>gb|AAC60791.1| phosphomevalonate kinase [Homo sapiens]
Length = 160
Score = 263 bits (672), Expect = 6e-69, Method: Composition-based stats.
Identities = 160/160 (100%), Positives = 160/160 (100%)
Query: 33 LGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFC 92
LGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFC
Sbjct: 1 LGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFC 60
Query: 93 RKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDA 152
RKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDA
Sbjct: 61 RKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDA 120
Query: 153 ESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
ESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL
Sbjct: 121 ESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 160
>dbj|BAF62110.1| phosphomevalonate kinase [Bombyx mori]
Length = 186
Score = 254 bits (651), Expect = 2e-66, Method: Composition-based stats.
Identities = 85/183 (46%), Positives = 129/183 (70%), Gaps = 2/183 (1%)
Query: 7 APRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
+P+++LLFSGKRKSGKDF+T+ L+ L AD C ++++S P+K +A+E LN LL
Sbjct: 2 SPKIILLFSGKRKSGKDFLTDHLRHIL-ADKCEIIKISQPIKTHWAKEKNLNLNELLSEG 60
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGIS-QPIWLVSDTRRVSDIQWFREAYGAV 125
YKE +R +MI+W EE R D G FC+ E + +P+W+VSD RR +DI+WF+E YG +
Sbjct: 61 EYKEQYRLEMIKWSEEMRNKDYGCFCKAACENAAIKPVWIVSDIRRKTDIRWFKETYGDI 120
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLI 185
+TVR+ A +++R++RG+ F GVDDA SEC LD++ D+D V+ N LEEQL++++
Sbjct: 121 IRTVRITADDRTRKERGFQFQVGVDDATSECDLDDYNDWDVVVNNGEGRDSLEEQLDSIL 180
Query: 186 EFI 188
+ +
Sbjct: 181 KLV 183
>ref|XP_001120920.1| PREDICTED: similar to Phosphomevalonate kinase (PMKase) [Apis
mellifera]
Length = 202
Score = 253 bits (648), Expect = 4e-66, Method: Composition-based stats.
Identities = 75/186 (40%), Positives = 119/186 (63%), Gaps = 5/186 (2%)
Query: 6 GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDT 65
P+++LLFSGKRK GKD++T L R+G+D ++++S P+K +A+ HGLN +L+
Sbjct: 18 SKPKIILLFSGKRKCGKDYITNILYERIGSDNSVIIKISAPIKSHWAKSHGLNIDQLMGD 77
Query: 66 STYKEAFRKDMIRWGEEKRQADPGFFCRKIVE---GISQPIWLVSDTRRVSDIQWFREAY 122
YKE +R +M +WGE R D G+FCR ++ + IW+VSD RR +DIQWF E +
Sbjct: 78 GKYKENYRLEMAKWGENIRNTDQGYFCRAALDIYNAYDKSIWIVSDIRRKTDIQWFTENF 137
Query: 123 GAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLE 182
+ +T+R+ + + R +RGW F G+DDAE+EC LD+ +D + N+ + +E L+
Sbjct: 138 KDICKTIRIESDDSIRIERGWTFVTGIDDAETECDLDDVNTWDLKVTNNT--KSIECILQ 195
Query: 183 NLIEFI 188
++E I
Sbjct: 196 QILELI 201
>ref|XP_001748282.1| predicted protein [Monosiga brevicollis MX1]
gb|EDQ87043.1| predicted protein [Monosiga brevicollis MX1]
Length = 234
Score = 252 bits (644), Expect = 1e-65, Method: Composition-based stats.
Identities = 99/186 (53%), Positives = 120/186 (64%), Gaps = 4/186 (2%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLG-ADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
P+LVLLFSGKRKSGKD++ + L R A V A +RLS PLK QYA +HGL++Q LL S
Sbjct: 51 PKLVLLFSGKRKSGKDYLADQLAQRPDLAPVLAQVRLSAPLKRQYALDHGLDYQELLSAS 110
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVT 126
TYKE R+ MI WGE+KR+ADPGFF R + PIWLV D RR +D+ +F+ Y
Sbjct: 111 TYKEQHRQAMIVWGEQKRRADPGFFARLATHDLQAPIWLVVDCRRQTDLTYFQTRYP--C 168
Query: 127 QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIE 186
TVRV A +R QRG+ FT GVDDAESECGLD D VI+N G Q L+ L+
Sbjct: 169 VTVRVQASVATRAQRGYTFTTGVDDAESECGLDAV-QHDIVIDNDGDGQATAAALDQLLA 227
Query: 187 FIRSRL 192
I L
Sbjct: 228 QIHQSL 233
>ref|NP_001040145.1| phosphomevalonate kinase [Bombyx mori]
gb|ABD36154.1| phosphomevalonate kinase [Bombyx mori]
Length = 186
Score = 249 bits (637), Expect = 7e-65, Method: Composition-based stats.
Identities = 84/183 (45%), Positives = 127/183 (69%), Gaps = 2/183 (1%)
Query: 7 APRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
+P+++LLFSGKRKSGKDF+T+ L+ L AD C ++++S P+K +A+E LN LL
Sbjct: 2 SPKIILLFSGKRKSGKDFLTDHLRHIL-ADKCEIIKISQPIKTHWAKEKNLNLNELLSEG 60
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGIS-QPIWLVSDTRRVSDIQWFREAYGAV 125
YKE +R +MI+W EE R D G FC+ E + +P+W+VSD RR +DI+WF+E YG +
Sbjct: 61 EYKEQYRLEMIKWSEEMRNKDYGCFCKAACENAAIKPVWIVSDIRRKTDIRWFKETYGDI 120
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLI 185
+TVR+ A +++R++RG+ F GVDDA SEC LD++ D D V+ N LEE L++++
Sbjct: 121 IRTVRITADDRTRKERGFQFQVGVDDATSECDLDDYNDGDVVVNNGEGRDSLEEPLDSIL 180
Query: 186 EFI 188
+ +
Sbjct: 181 KLV 183
>ref|XP_310779.4| AGAP000338-PA [Anopheles gambiae str. PEST]
gb|EAA06245.5| AGAP000338-PA [Anopheles gambiae str. PEST]
Length = 192
Score = 249 bits (637), Expect = 8e-65, Method: Composition-based stats.
Identities = 87/192 (45%), Positives = 119/192 (61%), Gaps = 4/192 (2%)
Query: 1 MAPLG-GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNF 59
MA + G PR++LL SGKRK GKDF+ +AL RLG D ++R+S P+K +A+ GL+
Sbjct: 1 MANVPDGVPRVLLLLSGKRKCGKDFLADALLQRLGTDRAQIVRISEPIKRHWAEAMGLDL 60
Query: 60 QRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFR 119
LL YKE +R+ MI W + +RQ D G FCR I +PI +VSD RR +D+++FR
Sbjct: 61 AALLGDGAYKERYRRQMIEWSDGRRQEDYGVFCRAACATIDRPICIVSDVRRQTDVRYFR 120
Query: 120 EAYG--AVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRL 177
EAYG +TVR+ A EQ R RGW F GVDD +SEC LD + +D V+ N +
Sbjct: 121 EAYGPETRLRTVRIEASEQVRHGRGWQFQAGVDDVQSECDLDGYAGWDLVLTNERP-DGV 179
Query: 178 EEQLENLIEFIR 189
E L+ L++ I
Sbjct: 180 GELLDRLVQLIE 191
>ref|XP_974268.1| PREDICTED: similar to Phosphomevalonate kinase (PMKase) [Tribolium
castaneum]
Length = 189
Score = 241 bits (617), Expect = 1e-62, Method: Composition-based stats.
Identities = 87/188 (46%), Positives = 122/188 (64%), Gaps = 6/188 (3%)
Query: 6 GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGL---NFQRL 62
PRL+LLFSGKRKSGKD++ EAL++ LG + C ++R+SGPLK YA+ H L + +
Sbjct: 2 ENPRLILLFSGKRKSGKDYICEALKANLGDNNCTIIRISGPLKRLYAESHDLTTGDVNEM 61
Query: 63 LDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGIS-QPIWLVSDTRRVSDIQWFREA 121
+ KE FR +MI+W +E R D GFFC+ + +P W+VSD RR +DI WF+
Sbjct: 62 MTDGPLKEKFRAEMIQWSDEIRGRDFGFFCKAATDLADLKPFWIVSDIRRKTDIHWFKNT 121
Query: 122 YGAVTQ-TVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ 180
Y +R+ A E +RQ+RGWVFT GVDD SEC LD+F D+D +I+N+ + L E
Sbjct: 122 YKDKIIKLIRIQADEVTRQKRGWVFTEGVDDVTSECDLDDFSDWDLIIKNN-NAEELGEG 180
Query: 181 LENLIEFI 188
L L++F+
Sbjct: 181 LGKLMQFL 188
>ref|XP_001604440.1| PREDICTED: similar to phosphomevalonate kinase [Nasonia
vitripennis]
Length = 204
Score = 241 bits (617), Expect = 2e-62, Method: Composition-based stats.
Identities = 76/184 (41%), Positives = 121/184 (65%), Gaps = 5/184 (2%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
P +L+FSGKRKSGKDF+T+ L +RLG + +++LSGP+K +A+ L+ ++L
Sbjct: 22 PEKILIFSGKRKSGKDFITDELFARLGKEKSVIIKLSGPIKSHWAKIKNLDAKQLFGDGE 81
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKI---VEGISQPIWLVSDTRRVSDIQWFREAYGA 124
YKEA+R++M +WGE+ R D G+FCR +PIW++SD RR +D++WF+E Y
Sbjct: 82 YKEAYRREMTKWGEDTRNKDYGYFCRAAILMYNANDKPIWIISDARRKTDLKWFKEHYAD 141
Query: 125 VTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENL 184
+T+R+ + E+ R+ RGW F G+DD+E+EC LD+ +D I N+G + +E L +
Sbjct: 142 KCKTIRISSSEEVRKNRGWKFCRGIDDSETECDLDDVTYWDLEINNNG--EDIELILHEI 199
Query: 185 IEFI 188
I+ +
Sbjct: 200 IDIL 203
>gb|EDM00620.1| phosphomevalonate kinase, isoform CRA_a [Rattus norvegicus]
Length = 147
Score = 239 bits (611), Expect = 8e-62, Method: Composition-based stats.
Identities = 119/140 (85%), Positives = 132/140 (94%)
Query: 53 QEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRV 112
QEHGL+FQ+LLD STYKE +R+DMI WGEEKRQADPGFFCRKIVEG+SQPIWLVSDTRR+
Sbjct: 6 QEHGLDFQKLLDASTYKETYRRDMICWGEEKRQADPGFFCRKIVEGVSQPIWLVSDTRRM 65
Query: 113 SDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHG 172
SDIQWF+EAYGA+TQTVRVVA EQSRQQRGWVFT GVDDAESECGLD+FGDFDWVIENHG
Sbjct: 66 SDIQWFQEAYGALTQTVRVVASEQSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENHG 125
Query: 173 VEQRLEEQLENLIEFIRSRL 192
EQ LE+QLENL+EFI ++L
Sbjct: 126 DEQCLEDQLENLLEFIHAKL 145
>ref|XP_001635081.1| predicted protein [Nematostella vectensis]
gb|EDO43018.1| predicted protein [Nematostella vectensis]
Length = 192
Score = 238 bits (608), Expect = 2e-61, Method: Composition-based stats.
Identities = 95/192 (49%), Positives = 129/192 (67%), Gaps = 9/192 (4%)
Query: 4 LGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLL 63
+ P V + SGKRKSGKD+V E L+ LG C +LRLSGPLK +YA+ H L++Q+LL
Sbjct: 1 MAAKPFAVCILSGKRKSGKDYVAERLKILLGKSNCEILRLSGPLKREYARIHKLDYQKLL 60
Query: 64 DTSTYKEAFRKDMIRWGEEKRQADPGFFCRKI-------VEGISQPIWLVSDTRRVSDIQ 116
D+S YKE +RKDMI+WGEEKR A+P +FC + ++ WLVSD RR++D+Q
Sbjct: 61 DSSDYKEKYRKDMIKWGEEKRNAEPYYFCELAAKMAYRDAQSETKLYWLVSDARRITDLQ 120
Query: 117 WFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQR 176
+F++ Y V VRV A + R +RGW+FT GVDDAESECGLD+ FD I N+G ++
Sbjct: 121 FFQQHYPRVVH-VRVTASDDVRMRRGWMFTNGVDDAESECGLDDV-IFDVAIINNGDNEQ 178
Query: 177 LEEQLENLIEFI 188
LE L +L + +
Sbjct: 179 LENSLASLKDKL 190
>gb|AAW26333.1| SJCHGC02790 protein [Schistosoma japonicum]
Length = 202
Score = 231 bits (590), Expect = 2e-59, Method: Composition-based stats.
Identities = 76/193 (39%), Positives = 120/193 (62%), Gaps = 10/193 (5%)
Query: 10 LVLLFSGKRKSGKDFVTEALQSRLGADVCA--VLRLSGPLKEQYAQEHGLNFQRLLDTST 67
+ ++FSGKRKSGKD+ L + L ++ + V+R+S P+K +A+ +GLN LL ++
Sbjct: 7 ICVVFSGKRKSGKDYTVNHLTNLLQSNHLSYLVVRISEPIKSYFAEHYGLNLSELLSSNE 66
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKI------VEGISQP-IWLVSDTRRVSDIQWFRE 120
YKE +RK MI W E++ + DP F RK GISQP + ++SD RRV+DI++ +
Sbjct: 67 YKENYRKQMISWMEQEIKQDPYVFIRKSLLESTRRHGISQPAVIIISDARRVNDIEYLIK 126
Query: 121 AYG-AVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEE 179
+G + VR+VA + R +RGW + GVD+A SECGLD F ++D+++ N+G + E
Sbjct: 127 TFGRSKCLLVRIVAPIEIRTERGWTYVNGVDNAASECGLDEFTNWDYIVSNNGDKSVFEN 186
Query: 180 QLENLIEFIRSRL 192
L ++ I+ L
Sbjct: 187 HLHVIVAHIKRML 199
>ref|XP_001270504.1| phosphoribosyl transferase domain protein [Aspergillus clavatus
NRRL 1]
gb|EAW09078.1| phosphoribosyl transferase domain protein [Aspergillus clavatus
NRRL 1]
Length = 1164
Score = 227 bits (579), Expect = 4e-58, Method: Composition-based stats.
Identities = 45/214 (21%), Positives = 81/214 (37%), Gaps = 26/214 (12%)
Query: 3 PLGGAP---RLVLLFSGKRKSGKDFVTEALQSRLGAD-----VCAVLRLSGPLKEQYAQE 54
PL P +L++L +G +GKD+ E S + +S K +YA +
Sbjct: 762 PLPETPVETKLIILVTGDSCAGKDYCAEIWVSAFTEYAHKRLTARSVSISDATKREYAAQ 821
Query: 55 HGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGF----FCRKIVEGISQPIWLVSDTR 110
G + RL+ YKE R + + +++ Q P F + + + L++ R
Sbjct: 822 TGADLNRLIRDRAYKEQHRPALTSFFQDQVQHRPQLLQEHFLDVVHGAVDVDVLLITGMR 881
Query: 111 RVSDIQWFREAYGA-VTQTVRVVALEQSRQQRGWVFTPGVDDAESE---------CGLDN 160
+ + VRV A E++R+ R + G D +++ LD
Sbjct: 882 DEAPVAGLSHLVPDSRLLDVRVQASEETRRARRGCCSSGDDRNDNKDSNNGGLNPTALDY 941
Query: 161 FGDFDWVIENHGVEQRLEEQL--ENLIEFIRSRL 192
F + +N ++L E L+ F L
Sbjct: 942 RPSF--IFKNDAPGDEAAKKLAEERLLPFFHEDL 973
>ref|XP_001357257.1| GA10206-PA [Drosophila pseudoobscura]
gb|EAL34326.1| GA10206-PA [Drosophila pseudoobscura]
Length = 185
Score = 226 bits (577), Expect = 6e-58, Method: Composition-based stats.
Identities = 76/182 (41%), Positives = 116/182 (63%), Gaps = 6/182 (3%)
Query: 11 VLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKE 70
++L SGKRK GKD+++E LQ RL + ++R+S P+K ++A++ L+ LL YKE
Sbjct: 4 IVLISGKRKCGKDYISERLQKRLT-NRAIIVRISEPIKSEWARKLQLDLSALLSDGPYKE 62
Query: 71 AFRKDMIRWGEEKRQADPGFFCRKIVEGISQP---IWLVSDTRRVSDIQWFREAYGA-VT 126
+R+DMI W +E R D G+FCR +E +VSD RR +DI+WFRE YG +
Sbjct: 63 QYRRDMIVWSDEVRSKDYGYFCRAAMEEAPLDQIAYVIVSDVRRKNDIKWFRETYGQNMV 122
Query: 127 QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIEN-HGVEQRLEEQLENLI 185
+TVR+ + ++RQ RGW FT G+DD SEC LD++ FD+V+ N +Q +QL +++
Sbjct: 123 RTVRLTSRPETRQARGWTFTKGIDDVPSECDLDDYDSFDFVVPNEDENDQGFIDQLLDML 182
Query: 186 EF 187
+
Sbjct: 183 QL 184
>ref|XP_001664006.1| phosphomevalonate kinase, putative [Aedes aegypti]
gb|EAT33914.1| phosphomevalonate kinase, putative [Aedes aegypti]
Length = 187
Score = 225 bits (574), Expect = 1e-57, Method: Composition-based stats.
Identities = 84/183 (45%), Positives = 122/183 (66%), Gaps = 1/183 (0%)
Query: 7 APRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
PR+VLLFSGKRK GKDF+TE L RL D ++R+S P+K +A++ GL+ LL
Sbjct: 6 VPRVVLLFSGKRKCGKDFLTERLLQRLTTDKAQIIRISEPIKRSWAEKLGLDLGELLGDG 65
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVT 126
YKE +RK+MI W ++KR D GFFCR+ +++ I +VSD RR +D+++FRE YG
Sbjct: 66 PYKERYRKEMIEWSDQKRAEDFGFFCRQACLALAKEICVVSDIRRKTDVRFFREQYGQRI 125
Query: 127 QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIE 186
+TVR+VA E +R +RGWVF GVDD +SEC LD+ ++D +++N +E L +I
Sbjct: 126 KTVRIVASEATRVERGWVFQEGVDDVQSECDLDDVTEWDLLVQNDSGAD-VENILARIIA 184
Query: 187 FIR 189
++
Sbjct: 185 LVQ 187
>ref|NP_872133.1| F32D8.13 [Caenorhabditis elegans]
emb|CAD66220.1| Hypothetical protein F32D8.13 [Caenorhabditis elegans]
Length = 187
Score = 222 bits (566), Expect = 1e-56, Method: Composition-based stats.
Identities = 78/184 (42%), Positives = 111/184 (60%), Gaps = 7/184 (3%)
Query: 10 LVLLFSGKRKSGKDFVTEALQSRL--GADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
+V+ SGKRKSGKD+ T ++ L +V +S LK ++A++HGL ++ LL
Sbjct: 3 IVIAISGKRKSGKDYCTNLIREVLVQKRFDVSVAGISHSLKMEFAKKHGLKYEELLTDGP 62
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEG-ISQPIWLVSDTRRVSDIQWFREAYGAVT 126
YKE +RKDMI+WGEE R D G FCR + + I ++SD RR +D ++F Y T
Sbjct: 63 YKELYRKDMIQWGEEARCKDSGLFCRAAISSTMDSDIVIISDCRRRTDYEYFSANY--RT 120
Query: 127 QTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIE 186
T+R+ E+ R+QRG+ F GVDDAESECGLD++ F+ VI+N L +QL + E
Sbjct: 121 VTIRIETSEEDRKQRGYQFVEGVDDAESECGLDDY-KFNLVIKNQSGTD-LSQQLNMVTE 178
Query: 187 FIRS 190
I
Sbjct: 179 KISR 182
>gb|ABF18214.1| phosphomevalonate kinase [Aedes aegypti]
Length = 187
Score = 221 bits (563), Expect = 2e-56, Method: Composition-based stats.
Identities = 82/184 (44%), Positives = 120/184 (65%), Gaps = 1/184 (0%)
Query: 6 GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDT 65
PR+VLLF GKRK GKDF+TE L RL D ++R+S P+K +A++ GL+ LL
Sbjct: 5 AVPRVVLLFFGKRKCGKDFLTERLLQRLTTDKAQIIRISEPIKRSWAEKLGLDLGELLGD 64
Query: 66 STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAV 125
YKE +RK+MI W ++KR D GFFCR+ +++ I +VSD RR +D+++FRE YG
Sbjct: 65 GPYKERYRKEMIEWSDQKRAEDFGFFCRQACLALAKEICVVSDIRRKTDVRFFREQYGQR 124
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLI 185
+TVR+VA E +R +RGWVF GVDD +SEC LD+ ++D +++N +E L ++
Sbjct: 125 IKTVRIVASEATRVERGWVFQEGVDDVQSECDLDDVTEWDLLVQNDSGAD-VENILARIV 183
Query: 186 EFIR 189
+
Sbjct: 184 ALAQ 187
>sp|Q29081|PMVK_PIG Phosphomevalonate kinase (PMKase)
Length = 130
Score = 218 bits (557), Expect = 1e-55, Method: Composition-based stats.
Identities = 116/129 (89%), Positives = 124/129 (96%)
Query: 1 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ 60
MAPLG PRLVLLFSGKRK GKDFVTEALQSRLGADVCA+LRLSGPLKEQYAQEHGL+FQ
Sbjct: 1 MAPLGSVPRLVLLFSGKRKDGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQ 60
Query: 61 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE 120
RLLD STYKE++RKDMIRWG+EKRQADPGFFCRKIVEG+SQPIWLVSDTRR+SDIQWF+E
Sbjct: 61 RLLDASTYKESYRKDMIRWGQEKRQADPGFFCRKIVEGVSQPIWLVSDTRRLSDIQWFQE 120
Query: 121 AYGAVTQTV 129
YGAVTQTV
Sbjct: 121 TYGAVTQTV 129
>ref|XP_001673885.1| Hypothetical protein CBG09742 [Caenorhabditis briggsae AF16]
Length = 188
Score = 217 bits (553), Expect = 4e-55, Method: Composition-based stats.
Identities = 79/169 (46%), Positives = 104/169 (61%), Gaps = 6/169 (3%)
Query: 9 RLVLLFSGKRKSGKDFVTEALQSRLGA--DVCAVLRLSGPLKEQYAQEHGLNFQRLLDTS 66
+ V+ SGKRKSGKD+ T L + + +S LKE+YA+ H LNF LL
Sbjct: 3 KFVIAISGKRKSGKDYCTNKLIKAFEKIQLSVSAVGISHSLKEEYAKIHNLNFAELLTDG 62
Query: 67 TYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGI-SQPIWLVSDTRRVSDIQWFREAYGAV 125
YKE FRKDMIRWGE+ R P FCR + + I +VSD RR++D+++F Y
Sbjct: 63 PYKEQFRKDMIRWGEDVRNKIPSVFCRAALLSVDDSDIVIVSDCRRITDLEFFVSNY--K 120
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVE 174
T TVRV +E+ RQQRG+ F G+DDAESECGLD++ FD V++N E
Sbjct: 121 TLTVRVETIEEHRQQRGFRFVKGIDDAESECGLDDY-KFDVVLKNITGE 168
>ref|NP_001089752.1| hypothetical protein LOC734816 [Xenopus laevis]
gb|AAI06478.1| MGC131201 protein [Xenopus laevis]
Length = 145
Score = 216 bits (550), Expect = 9e-55, Method: Composition-based stats.
Identities = 99/143 (69%), Positives = 117/143 (81%)
Query: 6 GAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDT 65
G PRLVLLFSGKRKSGKD VT +LQ R +D C+VLRLSGPLKEQ+A E GL+++RLL
Sbjct: 2 GEPRLVLLFSGKRKSGKDHVTNSLQLRFSSDTCSVLRLSGPLKEQFALERGLDYERLLGA 61
Query: 66 STYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAV 125
+ YKE FR DMIRWGEEKR+ DPGFFCR IV+ +SQP+W++SD RR SDI WFR YGAV
Sbjct: 62 TGYKEEFRADMIRWGEEKRRRDPGFFCRIIVQRVSQPVWIISDARRKSDIDWFRSEYGAV 121
Query: 126 TQTVRVVALEQSRQQRGWVFTPG 148
QTVRV A E++R+ RGWV+TPG
Sbjct: 122 LQTVRVEASEETREARGWVYTPG 144
>ref|NP_609992.1| CG10268 CG10268-PA [Drosophila melanogaster]
sp|Q9VIT2|PMVK_DROME Probable phosphomevalonate kinase (PMKase)
gb|AAF53833.1| CG10268-PA [Drosophila melanogaster]
Length = 189
Score = 214 bits (547), Expect = 2e-54, Method: Composition-based stats.
Identities = 81/188 (43%), Positives = 114/188 (60%), Gaps = 13/188 (6%)
Query: 11 VLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKE 70
++L SGKRK GKD+++E LQ RLG+ C ++R+S P+K ++A++ L+ LL YKE
Sbjct: 4 IVLISGKRKCGKDYISERLQRRLGSRSC-IVRISEPIKSEWARKLQLDLDALLGDGPYKE 62
Query: 71 AFRKDMIRWGEEKRQADPGFFCRKIVEGI----SQPIWLVSDTRRVSDIQWFREAYGA-V 125
+R+DMI W +E R D G+FCR +E P LVSD RR +DI+WFRE YG
Sbjct: 63 KYRRDMIVWSDEVRAQDYGYFCRVAMEEALSRQQTPYILVSDVRRKNDIRWFRETYGPER 122
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGD-FDWVIENHGVEQRLEEQLENL 184
T+R+ + ++R RGW FT G+DD SEC LD+ D FD V+ N EE +
Sbjct: 123 VITLRLTSRPETRSARGWTFTAGIDDVPSECDLDDLADGFDVVLAND------EELDQEA 176
Query: 185 IEFIRSRL 192
I+ + RL
Sbjct: 177 IDILLDRL 184
>gb|AAM51057.1| SD12705p [Drosophila melanogaster]
Length = 189
Score = 214 bits (547), Expect = 2e-54, Method: Composition-based stats.
Identities = 81/188 (43%), Positives = 113/188 (60%), Gaps = 13/188 (6%)
Query: 11 VLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKE 70
++L SGKRK GKD+++E LQ RLG+ C ++R+S P+K ++A + L+ LL YKE
Sbjct: 4 IVLISGKRKCGKDYISERLQRRLGSRSC-IVRISEPIKSEWAHKLQLDLDALLGDGPYKE 62
Query: 71 AFRKDMIRWGEEKRQADPGFFCRKIVEGI----SQPIWLVSDTRRVSDIQWFREAYGA-V 125
+R+DMI W +E R D G+FCR +E P LVSD RR +DI+WFRE YG
Sbjct: 63 KYRRDMIVWSDEVRAQDYGYFCRVAMEEALSRQQTPYILVSDVRRKNDIRWFRETYGPER 122
Query: 126 TQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGD-FDWVIENHGVEQRLEEQLENL 184
T+R+ + ++R RGW FT G+DD SEC LD+ D FD V+ N EE +
Sbjct: 123 VITLRLTSRPETRSARGWTFTAGIDDVPSECDLDDLADGFDVVLAND------EELDQEA 176
Query: 185 IEFIRSRL 192
I+ + RL
Sbjct: 177 IDILLDRL 184
>ref|XP_001866014.1| phosphomevalonate kinase [Culex pipiens quinquefasciatus]
gb|EDS42634.1| phosphomevalonate kinase [Culex pipiens quinquefasciatus]
Length = 186
Score = 214 bits (546), Expect = 3e-54, Method: Composition-based stats.
Identities = 78/188 (41%), Positives = 117/188 (62%), Gaps = 8/188 (4%)
Query: 8 PRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTST 67
PR+VLLFSGKRK GKD++TE L RL ++R+S P+K +A + GL+ LL
Sbjct: 4 PRIVLLFSGKRKCGKDYLTERLLQRLTPARAQIVRISEPIKRCWADKLGLDLGELLGDGP 63
Query: 68 YKEAFRKDMIRWGEEKRQADPGFFCRKIVEG---ISQPIWLVSDTRRVSDIQWFREAYGA 124
YKE +R++MI W + +R D GFFCR ++ + +VSD RR +D+++FRE +G
Sbjct: 64 YKERYRREMIEWSDGRRAEDYGFFCRAACSEGVVAAREVCIVSDVRRKTDVRFFRETFGE 123
Query: 125 VTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENL 184
+TVR+VA E++R +RGW F GVDD +SEC LD+ ++D ++EN +E +
Sbjct: 124 RVRTVRIVAGEETRTERGWKFQQGVDDVQSECDLDDVTEWDLLVENEAGAD-----VEGI 178
Query: 185 IEFIRSRL 192
+ I + L
Sbjct: 179 LARIEALL 186
>ref|XP_001801140.1| hypothetical protein SNOG_10882 [Phaeosphaeria nodorum SN15]
gb|EAT81381.2| hypothetical protein SNOG_10882 [Phaeosphaeria nodorum SN15]
Length = 1625
Score = 206 bits (525), Expect = 8e-52, Method: Composition-based stats.
Identities = 46/184 (25%), Positives = 71/184 (38%), Gaps = 16/184 (8%)
Query: 3 PLGG---APRLVLLFSGKRKSGKDFVTEALQSRLGADV-----CAVLRLSGPLKEQYAQE 54
PL P+L+ L +G +GKD+ E S + + +S K YA
Sbjct: 677 PLPKNRPGPKLIFLVTGNHGAGKDYCAEQWASEVKDHARERLEVHISSISDATKRAYAAS 736
Query: 55 HGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGF----FCRKIVEGISQPIWLVSDTR 110
G + RLL+ YKE R M + + + Q P F + + ++ R
Sbjct: 737 TGADLARLLNDRAYKEQHRAAMTAFFKAQVQQRPNLPEEHFLDVVYGAAEADVLFITGMR 796
Query: 111 RVSDIQWFREAY-GAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECG-LDNFGDFDWVI 168
+ + F G+ VRV A E+ R PGV + E+ LD DFD
Sbjct: 797 DPAPVAMFSHLVPGSRVIEVRVRASEEIIYNRRCCDGPGVAERETASALLDWCPDFD--F 854
Query: 169 ENHG 172
+N+
Sbjct: 855 DNNV 858
>gb|AAH28659.1| Pmvk protein [Mus musculus]
Length = 117
Score = 204 bits (521), Expect = 2e-51, Method: Composition-based stats.
Identities = 100/117 (85%), Positives = 110/117 (94%)
Query: 76 MIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALE 135
MI WGE+KRQADPGFFCRKIVEG+SQPIWLVSDTRR SDIQWF+EAYGAV QTVRVVA E
Sbjct: 1 MICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQEAYGAVIQTVRVVASE 60
Query: 136 QSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
QSRQQRGWVFTPGVDDAESECGLDNFG+FDWVIENHG EQ LE+QLE+L+ FI+++L
Sbjct: 61 QSRQQRGWVFTPGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQLEHLLGFIQAKL 117
>ref|XP_001818778.1| hypothetical protein [Aspergillus oryzae RIB40]
dbj|BAE56776.1| unnamed protein product [Aspergillus oryzae]
Length = 1159
Score = 203 bits (518), Expect = 4e-51, Method: Composition-based stats.
Identities = 47/216 (21%), Positives = 78/216 (36%), Gaps = 30/216 (13%)
Query: 3 PLGGA---PRLVLLFSGKRKSGKDFVTEALQSRLGADV-----CAVLRLSGPLKEQYAQE 54
PL RL++L +G +GKD+ + S L A + +S K +YA
Sbjct: 757 PLPRVSMKQRLIILVTGDSCAGKDYCADIWVSALLAYNHKGLTARAVSISDATKREYATA 816
Query: 55 HGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGF----FCRKIVEGISQPIWLVSDTR 110
G + RLL YKE R + + +++ + P F + + L++ R
Sbjct: 817 TGADLNRLLSDRAYKEQHRPALTAFFQDQVRHRPRLPEEHFLNVVDSAADVDVLLITGMR 876
Query: 111 RVSDIQWFREAYGA-VTQTVRVVALEQSRQQRGWVFTPGVDDAE-----------SECGL 158
+ + F VRV A E+ R+ RG G DD + L
Sbjct: 877 DEAPVATFSHLVPDARLLEVRVQAGEEMRRARGGC--HGSDDDSNDNKNNDNGRLNLTAL 934
Query: 159 DNFGDFDWVIENHGVEQRLEEQLEN--LIEFIRSRL 192
D+ D + N + + + L+ F L
Sbjct: 935 DHHP--DLIFHNDTTGDKAAKAFADYYLLPFCHEDL 968
>gb|EDM00621.1| phosphomevalonate kinase, isoform CRA_b [Rattus norvegicus]
Length = 119
Score = 202 bits (516), Expect = 8e-51, Method: Composition-based stats.
Identities = 102/117 (87%), Positives = 111/117 (94%)
Query: 76 MIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALE 135
MI WGEEKRQADPGFFCRKIVEG+SQPIWLVSDTRR+SDIQWF+EAYGA+TQTVRVVA E
Sbjct: 1 MICWGEEKRQADPGFFCRKIVEGVSQPIWLVSDTRRMSDIQWFQEAYGALTQTVRVVASE 60
Query: 136 QSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL 192
QSRQQRGWVFT GVDDAESECGLD+FGDFDWVIENHG EQ LE+QLENL+EFI ++L
Sbjct: 61 QSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENHGDEQCLEDQLENLLEFIHAKL 117
>ref|XP_001211374.1| conserved hypothetical protein [Aspergillus terreus NIH2624]
gb|EAU37158.1| conserved hypothetical protein [Aspergillus terreus NIH2624]
Length = 1102
Score = 198 bits (504), Expect = 2e-49, Method: Composition-based stats.
Identities = 42/213 (19%), Positives = 77/213 (36%), Gaps = 32/213 (15%)
Query: 3 PLG---GAPRLVLLFSGKRKSGKDFVTEALQSRLGAD-----VCAVLRLSGPLKEQYAQE 54
PL A +L++L +GK +GKD+ S V + +S K YA
Sbjct: 709 PLPKASAAQKLIILVTGKCGAGKDYCANVWVSAFTNATQRHLVARAVSISEATKRGYAVA 768
Query: 55 HGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGF----FCRKIVEGISQPIWLVSDTR 110
G + +RLL YKE R + + +++ + P F + + + L++ R
Sbjct: 769 TGADLERLLSDRVYKEQHRSKLTEFFQDQVRQRPRLPEEHFLDVVHNAVGVDVLLITGMR 828
Query: 111 RVSDIQWFREAYG-AVTQTVRVVALEQSRQQRGWVFTPGVDDAESECG-LDNFGDFDWVI 168
+ + + V + ++ R+ R G D+ +S LD+ V
Sbjct: 829 DEAPVATLSHLVPASRVLEVYIRTSDEIRKVRR---QGGGDNNDSHSTVLDHSPS--LVF 883
Query: 169 ENHGVEQR-------------LEEQLENLIEFI 188
EN ++L+ L E +
Sbjct: 884 ENDQTGDEKAKRFAENYLLPFFGDELQRLAEMV 916
>ref|XP_001224477.1| hypothetical protein CHGG_06821 [Chaetomium globosum CBS 148.51]
gb|EAQ85568.1| hypothetical protein CHGG_06821 [Chaetomium globosum CBS 148.51]
Length = 1109
Score = 196 bits (498), Expect = 9e-49, Method: Composition-based stats.
Identities = 41/212 (19%), Positives = 72/212 (33%), Gaps = 24/212 (11%)
Query: 3 PLGGAP---RLVLLFSGKRKSGKDFVTEALQSRLG--ADVCAVLRLSGPLKEQYAQEHGL 57
PL G P +L++L +G+ +GKD+ + + +S K +YA G
Sbjct: 710 PLPGVPMEPKLIVLVTGEHGAGKDYCADLWVEFFNNNKFRAQAVSISDATKREYASATGA 769
Query: 58 NFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGF----FCRKIVEGISQPIWLVSDTRRVS 113
N RL YKE R + + + + P F + + V+ R +
Sbjct: 770 NLDRLFQDRAYKEQHRPALTSYFQAQVYQRPRLLEEHFLSAVHGASGIDVLFVTGMRDEA 829
Query: 114 DIQWFREAY-GAVTQTVRVVALEQSRQQRGW-------VFTPGVDDAESECGL---DNFG 162
+ G+ V V E++R+ R V D+ + GL D+
Sbjct: 830 PVATMSHLVPGSRLLEVSVETHEETRRARRGYLKADDVVQVRSKDNENQKSGLVVTDSRP 889
Query: 163 DFDWVIENHGVEQRLEE--QLENLIEFIRSRL 192
+ N + L+ F+ L
Sbjct: 890 S--LIFSNDTAGSEAGATFAEQQLLPFLHEDL 919
>ref|XP_359731.1| hypothetical protein MGG_05046 [Magnaporthe grisea 70-15]
gb|EDJ95364.1| hypothetical protein MGG_05046 [Magnaporthe grisea 70-15]
Length = 1172
Score = 185 bits (470), Expect = 2e-45, Method: Composition-based stats.
Identities = 41/222 (18%), Positives = 76/222 (34%), Gaps = 34/222 (15%)
Query: 5 GGAPRLVLLFSGKRKSGKDFVTEALQSRLGADV-------CAVLRLSGPLKEQYAQEHGL 57
P+L++L +G +GKD+ S + + +S K +YA+ G
Sbjct: 760 PTEPKLIILVTGLHGAGKDYCAAIWVSVFNSSNPARKYPTACAIGISDATKREYAEATGA 819
Query: 58 NFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGF----FCRKIVEGISQPIWLVSDTRRVS 113
+F RLL YKE R + + + + + P F + + + + L++ R +
Sbjct: 820 DFDRLLSDRPYKEQHRSGLNAFFKSQLRRRPRLPEEHFLKVVRDSAPIDVLLITGMREQA 879
Query: 114 DIQWFREAYG-AVTQTVRVVALEQSRQQRGWVFTP---GVDDAESECGLDNFGDF----- 164
+ + VRV E+ RQ R G + + C ++ D
Sbjct: 880 PVAALSHLVPKSKLLEVRVTVSEELRQVRRGSRKDLAIGRGNCAALCAAEDGTDGEGIKH 939
Query: 165 ------------DWVIENHGVEQRLEEQL--ENLIEFIRSRL 192
D EN + + + L+ I L
Sbjct: 940 ARLGSMTSSDCPDLTFENDIPGSKAVKAFAQDRLLPLIHEDL 981
>ref|XP_383779.1| hypothetical protein FG03603.1 [Gibberella zeae PH-1]
Length = 1136
Score = 181 bits (461), Expect = 2e-44, Method: Composition-based stats.
Identities = 37/199 (18%), Positives = 80/199 (40%), Gaps = 14/199 (7%)
Query: 7 APRLVLLFSGKRKSGKDFVTEALQSRLGAD--VCAVLRLSGPLKEQYAQEHGLNFQRLLD 64
+ ++V+L +G+ +GKD+ + + V+ + K +YA + G + +RLL
Sbjct: 749 SQKMVVLVTGEHGAGKDYCANVWAAAVKGHGYSTTVIGIGDVTKREYASQRGADSERLLG 808
Query: 65 TSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGI---SQPIWLVSDTRRVSDIQWFREA 121
YKE R+ + + ++ + P VE + + + ++ R + +
Sbjct: 809 DRVYKEQHREALAAFFNQQLEHRPHLAEEHFVESVRSANVDVLFITGMREEAPVANLWHL 868
Query: 122 YGA-VTQTVRVVALEQSRQQRGWVFTPG-----VDDAESECGLDNFGDFDWVIENH--GV 173
+ V A ++R R +FT G +E + N+ ++V +N
Sbjct: 869 VSDVRLVDIHVNASHKTRGLRRQIFTNGHSISRGSFNCTETLVSNYR-PNFVFDNDIASD 927
Query: 174 EQRLEEQLENLIEFIRSRL 192
+Q +L F+ + L
Sbjct: 928 DQVKAFAKYSLFPFLGNDL 946
>ref|XP_001907258.1| unnamed protein product [Podospora anserina]
emb|CAP67929.1| unnamed protein product [Podospora anserina]
Length = 1160
Score = 181 bits (461), Expect = 2e-44, Method: Composition-based stats.
Identities = 42/186 (22%), Positives = 71/186 (38%), Gaps = 16/186 (8%)
Query: 3 PLGG---APRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLS--GPLKEQYAQEHGL 57
PL P+L++L +G+ +GKDF S + S K YA G
Sbjct: 773 PLPAPPKDPKLIVLVTGESGAGKDFCAGVWVSLFTKNSITSSVSSISEATKRAYATASGA 832
Query: 58 NFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGF----FCRKIVEGISQPIWLVSDTRRVS 113
+ RLL+ YKE R + + + + P F +V G + ++ R +
Sbjct: 833 DLNRLLEDRDYKEQHRTALTTFFQNQVNERPQLPREHFLE-VVHGADSDVLFITGMRDKT 891
Query: 114 DIQWFREAY-GAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHG 172
+ F G+ VR+ A E+ R+ R + T G D ++E + I N+
Sbjct: 892 PVVAFSHLVPGSKLLEVRIEASEKIRRVRRGLETSGATDEKAE---KHTPS--ITISNNA 946
Query: 173 VEQRLE 178
+
Sbjct: 947 EGKSAA 952
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.313 0.176 0.513
Lambda K H
0.267 0.0539 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,608,207,055
Number of Sequences: 6899187
Number of extensions: 198203879
Number of successful extensions: 464683
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 322
Number of HSP's successfully gapped in prelim test: 908
Number of HSP's that attempted gapping in prelim test: 463951
Number of HSP's gapped (non-prelim): 1285
length of query: 192
length of database: 2,350,152,223
effective HSP length: 127
effective length of query: 65
effective length of database: 1,473,955,474
effective search space: 95807105810
effective search space used: 95807105810
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 76 (33.5 bits)