BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= XP_822397.1__[Trypanosoma_brucei]
         (234 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           6,899,187 sequences; 2,350,152,223 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_822397.1|  hypoxanthine-guanine phosphoribosyltransfe...   471   e-131
ref|XP_813397.1|  hypoxanthine-guanine phosphoribosyltransfe...   298   3e-79
ref|XP_816917.1|  hypoxanthine-guanine phosphoribosyltransfe...   296   1e-78
ref|XP_001564805.1|  xanthine phosphoribosyltransferase [Lei...   263   7e-69
ref|XP_001683026.1|  xanthine phosphoribosyltransferase [Lei...   254   3e-66
gb|AAD50967.1|AF170105_2  xanthine phosphoribosyltransferase...   254   4e-66
ref|XP_001463948.1|  XRPT, xanthine phosphoribosyltransferas...   233   6e-60
ref|XP_822398.1|  hypoxanthine-guanine phosphoribosyltransfe...   161   3e-38
ref|XP_822405.1|  hypoxanthine-guanine phosphoribosyltransfe...   159   1e-37
sp|Q27541|HPRT_CRIFA  Hypoxanthine-guanine phosphoribosyltra...   141   4e-32
ref|XP_816916.1|  hypoxanthine-guanine phosphoribosyltransfe...   140   1e-31
pdb|1PZM|A  Chain A, Crystal Structure Of Hgprt-Ase From Lei...   139   1e-31
pdb|1TC2|A  Chain A, Ternary Substrate Complex Of The Hypoxa...   139   2e-31
pdb|1TC1|A  Chain A, A 1.4 Angstrom Crystal Structure For Th...   139   2e-31
ref|XP_001463947.1|  HGPRT,hypoxanthine-guanine phosphoribos...   138   3e-31
pdb|1P17|A  Chain A, Hypoxanthine Phosphoribosyltransferase ...   138   4e-31
pdb|1I14|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   137   6e-31
ref|XP_813396.1|  hypoxanthine-guanine phosphoribosyltransfe...   137   6e-31
pdb|1I0L|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   137   7e-31
ref|XP_001564804.1|  hypoxanthine-guanine phosphoribosyltran...   137   7e-31
ref|XP_001683025.1|  hypoxanthine-guanine phosphoribosyltran...   137   9e-31
pdb|1I0I|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   136   9e-31
pdb|1I13|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   136   1e-30
ref|YP_794711.1|  Hypoxanthine-guanine phosphoribosyltransfe...   131   5e-29
ref|YP_001916267.1|  hypoxanthine phosphoribosyltransferase ...   130   6e-29
gb|AAF61462.1|AF139722_1  hypoxanthine-guanine phosphoribosy...   127   7e-28
ref|NP_784322.1|  hypoxanthine-guanine phosphoribosyltransfe...   127   9e-28
ref|YP_001113711.1|  hypoxanthine phosphoribosyltransferase ...   125   3e-27
ref|YP_001512894.1|  hypoxanthine phosphoribosyltransferase ...   124   4e-27
gb|ABE47510.1|  hypoxanthine-guanine phosphoribosyltransfera...   124   5e-27
ref|YP_001319457.1|  hypoxanthine phosphoribosyltransferase ...   124   6e-27
ref|YP_002769603.1|  hypoxanthine-guanine phosphoribosyltran...   124   7e-27
gb|ABE47508.1|  hypoxanthine-guanine phosphoribosyltransfera...   123   1e-26
gb|ABE47509.1|  hypoxanthine-guanine phosphoribosyltransfera...   123   1e-26
ref|YP_001031384.1|  hypoxanthine phosphoribosyltransferase ...   123   1e-26
ref|YP_808076.1|  Hypoxanthine-guanine phosphoribosyltransfe...   122   1e-26
ref|ZP_01273646.1|  Hypoxanthine phosphoribosyl transferase ...   122   2e-26
ref|ZP_03939360.1|  hypoxanthine phosphoribosyltransferase [...   122   2e-26
ref|ZP_03958961.1|  hypoxanthine phosphoribosyltransferase [...   122   3e-26
ref|NP_266176.1|  hypoxantine-guanine phosphorybosyltransfer...   122   3e-26
ref|ZP_03952458.1|  hypoxanthine phosphoribosyltransferase [...   121   3e-26
ref|ZP_03942372.1|  hypoxanthine phosphoribosyltransferase [...   121   3e-26
ref|YP_001270874.1|  hypoxanthine phosphoribosyltransferase ...   121   4e-26
ref|YP_001513548.1|  hypoxanthine phosphoribosyltransferase ...   120   6e-26
ref|ZP_03974729.1|  hypoxanthine phosphoribosyltransferase [...   120   7e-26
ref|YP_074329.1|  hypoxanthine-guanine phosphoribosyltransfe...   120   8e-26
ref|ZP_03856512.1|  hypoxanthine phosphoribosyltransferase [...   120   9e-26
ref|ZP_00874757.1|  Hypoxanthine phosphoribosyl transferase ...   119   2e-25
ref|ZP_01666882.1|  hypoxanthine phosphoribosyltransferase [...   118   3e-25
emb|CAJ74742.1|  similar to hypoxanthine-guanine-xanthine ph...   118   3e-25
ref|YP_001213102.1|  hypoxanthine-guanine phosphoribosyltran...   118   3e-25
ref|YP_001197388.1|  Hypoxanthine-guanine phosphoribosyltran...   118   4e-25
ref|YP_536242.1|  Hypoxanthine-guanine phosphoribosyltransfe...   117   5e-25
ref|ZP_04009409.1|  hypoxanthine-guanine phosphoribosyltrans...   117   5e-25
ref|XP_001691549.1|  hypothetical protein CHLREDRAFT_145152 ...   117   6e-25
ref|YP_001843036.1|  hypoxanthine-guanine phosphoribosyltran...   117   6e-25
ref|ZP_03958058.1|  hypoxanthine-guanine phosphoribosyltrans...   116   1e-24
ref|YP_001034033.1|  Hypoxanthine guanine phosphoribosyltran...   116   1e-24
ref|ZP_02919438.1|  hypothetical protein STRINF_00277 [Strep...   116   1e-24
ref|ZP_02094407.1|  hypothetical protein PEPMIC_01173 [Pepto...   116   1e-24
ref|YP_805009.1|  Hypoxanthine-guanine phosphoribosyltransfe...   115   2e-24
ref|ZP_02091227.1|  hypothetical protein FAEPRAM212_01498 [F...   115   2e-24
ref|YP_001485312.1|  hypoxanthine phosphoribosyltransferase ...   115   2e-24
ref|YP_375425.1|  Hypoxanthine phosphoribosyl transferase [P...   115   3e-24
ref|ZP_01514399.1|  hypoxanthine phosphoribosyltransferase [...   115   3e-24
ref|YP_807706.1|  Hypoxanthine-guanine phosphoribosyltransfe...   115   3e-24
ref|ZP_02037643.1|  hypothetical protein BACCAP_03261 [Bacte...   114   5e-24
ref|ZP_02444150.1|  hypothetical protein ANACOL_03471 [Anaer...   114   5e-24
ref|YP_001320712.1|  hypoxanthine phosphoribosyltransferase ...   114   5e-24
ref|NP_814058.1|  hypoxanthine-guanine phosphoribosyltransfe...   114   5e-24
ref|ZP_02330217.1|  hypothetical protein Plarl_21636 [Paenib...   114   6e-24
ref|XP_001023170.1|  hypoxanthine phosphoribosyltransferase ...   113   1e-23
ref|YP_460761.1|  hypoxanthine-guanine phosphoribosyltransfe...   113   1e-23
ref|YP_302336.1|  putative hypoxanthine-guanine phosphoribos...   113   1e-23
ref|NP_344565.1|  hypoxanthine-guanine phosphoribosyltransfe...   112   1e-23
ref|ZP_01448574.1|  hypoxanthine phosphoribosyltransferase [...   112   2e-23
ref|ZP_02737445.1|  hypoxanthine-guanine phosphoribosyltrans...   112   2e-23
ref|YP_001717770.1|  hypoxanthine phosphoribosyltransferase ...   112   2e-23
ref|YP_845548.1|  hypoxanthine phosphoribosyltransferase [Sy...   112   3e-23
ref|ZP_00143803.1|  Hypoxanthine-guanine phosphoribosyltrans...   111   3e-23
ref|NP_998151.1|  hypoxanthine phosphoribosyltransferase 1 [...   111   4e-23
ref|ZP_01802750.1|  hypothetical protein CdifQ_04003751 [Clo...   111   4e-23
ref|NP_925736.1|  hypoxanthine phosphoribosyltransferase [Gl...   111   4e-23
ref|YP_001089748.1|  hypoxanthine phosphoribosyltransferase ...   111   4e-23
ref|YP_173609.1|  hypoxanthine-guanine phosphoribosyltransfe...   111   4e-23
ref|YP_001451359.1|  hypoxanthine phosphoribosyltransferase ...   111   5e-23
ref|ZP_02185480.1|  hypoxanthine-guanine phosphoribosyltrans...   111   5e-23
ref|ZP_01825459.1|  hypoxanthine phosphoribosyltransferase [...   110   6e-23
ref|NP_001090235.1|  phosphoribosyl transferase domain conta...   110   6e-23
ref|ZP_01189486.1|  Hypoxanthine phosphoribosyl transferase ...   110   6e-23
ref|YP_001647433.1|  hypoxanthine phosphoribosyltransferase ...   110   7e-23
ref|ZP_02272383.1|  Hypoxanthine-guanine phosphoribosyltrans...   110   8e-23
ref|YP_396211.1|  Hypoxanthine phosphoribosyltranferase [Lac...   110   9e-23
ref|ZP_03845145.1|  hypoxanthine-guanine phosphoribosyltrans...   110   9e-23
ref|ZP_02014261.1|  Hypoxanthine phosphoribosyltransferase [...   110   1e-22
gb|AAB59392.1|  hypoxanthine phosphoribosyltransferase            110   1e-22
ref|XP_001097691.1|  PREDICTED: similar to Hypoxanthine-guan...   109   1e-22
ref|NP_687051.1|  hypoxanthine-guanine phosphoribosyltransfe...   109   1e-22
ref|NP_989312.1|  hypoxanthine phosphoribosyltransferase 1 [...   109   1e-22
ref|NP_981268.1|  hypoxanthine-guanine phosphoribosyltransfe...   109   2e-22
ref|XP_001375158.1|  PREDICTED: similar to hypoxanthine phos...   109   2e-22
gb|EAX11760.1|  hypoxanthine phosphoribosyltransferase 1 (Le...   109   2e-22
gb|ABY56069.1|  hypoxanthine phosphoribosyltransferase [uncu...   109   2e-22
ref|ZP_02992594.1|  hypoxanthine phosphoribosyltransferase [...   109   2e-22
ref|YP_001376683.1|  hypoxanthine phosphoribosyltransferase ...   108   2e-22
emb|CAJ82941.1|  hypoxanthine phosphoribosyltransferase 1 (L...   108   2e-22
ref|ZP_02255942.1|  hypoxanthine-guanine phosphoribosyltrans...   108   2e-22
ref|NP_603195.1|  Hypoxanthine-guanine phosphoribosyltransfe...   108   3e-22
ref|NP_990179.1|  hypoxanthine phosphoribosyltransferase 1 (...   108   3e-22
gb|AAB59391.1|  hypoxanthine phosphoribosyltransferase            108   3e-22
gb|AAV38156.1|  hypoxanthine phosphoribosyltransferase 1 (Le...   108   3e-22
ref|NP_000185.1|  hypoxanthine phosphoribosyltransferase 1 [...   108   3e-22
gb|AAA96232.1|  hprt gene product                                 108   3e-22
pdb|1HMP|A  Chain A, The Crystal Structure Of Human Hypoxant...   108   3e-22
ref|XP_001514524.1|  PREDICTED: similar to hypoxanthine guan...   108   4e-22
gb|AAA41351.1|  hypoxanthine-guanine phosporibosyltransferase     108   4e-22
dbj|BAE01621.1|  unnamed protein product [Macaca fascicularis]    108   4e-22
ref|YP_644942.1|  hypoxanthine phosphoribosyltransferase [Ru...   108   4e-22
gb|ABB46192.1|  hypoxanthine 2 guanine phosphoribosyl transf...   108   4e-22
ref|XP_001490239.1|  PREDICTED: similar to hypoxanthine phos...   108   4e-22
ref|NP_036715.1|  hypoxanthine guanine phosphoribosyl transf...   108   4e-22
ref|YP_001820494.1|  hypoxanthine phosphoribosyltransferase ...   108   4e-22
dbj|BAG12569.1|  hypoxanthine phosphoribosyltransferase [Sol...   108   4e-22
ref|YP_001539489.1|  hypoxanthine phosphoribosyltransferase ...   108   4e-22
dbj|BAA34253.1|  hypoxanthine-guanine phosphoribosyl-transfe...   108   4e-22
emb|CAO80713.1|  Hypoxanthine-guanine phosphoribosyltransfer...   107   5e-22
ref|ZP_03916784.1|  hypoxanthine phosphoribosyltransferase [...   107   5e-22
gb|EDL84493.1|  rCG47045, isoform CRA_b [Rattus norvegicus]       107   5e-22
ref|ZP_01965205.1|  hypothetical protein RUMOBE_02936 [Rumin...   107   5e-22
ref|ZP_02210776.1|  hypothetical protein CLOBAR_00343 [Clost...   107   5e-22
ref|NP_825842.1|  hypoxanthine phosphoribosyltransferase [St...   107   5e-22
ref|YP_520172.1|  hypothetical protein DSY3939 [Desulfitobac...   107   5e-22
ref|YP_138556.1|  hypoxanthine-guanine phosphoribosyltransfe...   107   5e-22
ref|ZP_00603444.1|  Hypoxanthine phosphoribosyl transferase ...   107   5e-22
ref|NP_463750.1|  fusion protein, N-terminal part similar to...   107   6e-22
ref|ZP_01942347.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   107   6e-22
ref|ZP_01928838.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   107   6e-22
ref|ZP_01753405.1|  hypoxanthine phosphoribosyltransferase [...   107   6e-22
ref|ZP_01574690.1|  hypoxanthine phosphoribosyltransferase [...   107   6e-22
ref|YP_001232127.1|  hypoxanthine phosphoribosyltransferase ...   107   6e-22
ref|ZP_03982713.1|  Hypoxanthine phosphoribosyltransferase [...   107   6e-22
ref|ZP_01926199.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   107   6e-22
ref|ZP_02276207.1|  hypothetical protein LmonFS_00952 [Liste...   107   6e-22
ref|ZP_00230936.1|  conserved hypothetical protein/hypoxanth...   107   6e-22
ref|ZP_02686823.1|  hypothetical protein LmonFSL_00295 [List...   107   6e-22
ref|ZP_04008271.1|  hypoxanthine phosphoribosyltransferase [...   107   6e-22
ref|NP_627611.1|  hypoxanthine phosphoribosyltransferase [St...   107   6e-22
emb|CAG28573.1|  HPRT1 [Homo sapiens]                             107   6e-22
emb|CAA42198.1|  hypoxanthine (guanine) phosphoribosyltransf...   107   6e-22
ref|YP_012840.1|  conserved hypothetical protein/hypoxanthin...   107   6e-22
gb|AAR17061.1|  hypoxanthine phosphoribosyltransferase [Equu...   107   6e-22
ref|ZP_02993965.1|  hypothetical protein CLOSPO_01067 [Clost...   107   7e-22
ref|YP_002753307.1|  hypoxanthine phosphoribosyltransferase ...   107   7e-22
ref|NP_001003357.1|  hypoxanthine phosphoribosyltransferase ...   107   7e-22
ref|NP_177320.1|  phosphoribosyltransferase family protein [...   107   8e-22
ref|NP_001104287.1|  hypoxanthine phosphoribosyltransferase ...   107   8e-22
ref|YP_001545794.1|  hypoxanthine phosphoribosyltransferase ...   107   8e-22
ref|NP_834515.1|  hypoxanthine-guanine phosphoribosyltransfe...   107   8e-22
ref|YP_254416.1|  putative hypoxanthine-guanine phosphoribos...   107   9e-22
ref|YP_038863.1|  hypoxanthine-guanine phosphoribosyltransfe...   107   9e-22
gb|AAH04686.1|  Hypoxanthine guanine phosphoribosyl transfer...   107   9e-22
ref|XP_587503.2|  PREDICTED: similar to hypoxanthine phospho...   107   9e-22
ref|ZP_02849796.1|  hypoxanthine phosphoribosyltransferase [...   107   9e-22
prf||1009173A  transferase,HG phosphoribosyl                      107   1e-21
ref|YP_645559.1|  hypoxanthine phosphoribosyltransferase [Ru...   107   1e-21
ref|YP_613363.1|  hypoxanthine phosphoribosyltransferase [Si...   107   1e-21
ref|YP_001373429.1|  hypoxanthine phosphoribosyltransferase ...   107   1e-21
ref|YP_359913.1|  hypoxanthine phosphoribosyltransferase [Ca...   106   1e-21
ref|ZP_02478331.1|  hypoxanthine phosphoribosyltransferase [...   106   1e-21
ref|NP_038584.2|  hypoxanthine guanine phosphoribosyl transf...   106   1e-21
gb|EDL29120.1|  hypoxanthine guanine phosphoribosyl transfer...   106   1e-21
ref|YP_001311294.1|  hypoxanthine phosphoribosyltransferase ...   106   1e-21
ref|NP_847264.1|  hypoxanthine-guanine phosphoribosyltransfe...   106   1e-21
ref|ZP_02094616.1|  hypothetical protein PEPMIC_01383 [Pepto...   106   1e-21
ref|NP_469596.1|  fusion protein, N-terminal part similar to...   106   1e-21
ref|NP_001029207.1|  hypoxanthine phosphoribosyltransferase ...   106   1e-21
ref|ZP_01747148.1|  hypoxanthine phosphoribosyltransferase [...   106   1e-21
gb|ABF57418.1|  hypoxanthine phosphoribosyltransferase 1 [Bo...   106   1e-21
ref|NP_662412.1|  hypoxanthine-guanine phosphoribosyltransfe...   106   1e-21
pdb|1D6N|A  Chain A, Ternary Complex Structure Of Human Hgpr...   106   1e-21
ref|YP_001161115.1|  hypoxanthine phosphoribosyltransferase ...   106   1e-21
ref|ZP_02949925.1|  hypoxanthine phosphoribosyltransferase [...   106   1e-21
ref|YP_001635640.1|  hypoxanthine phosphoribosyltransferase ...   106   1e-21
sp|Q64531|HPRT_MUSSP  Hypoxanthine-guanine phosphoribosyltra...   106   1e-21
ref|NP_213381.1|  hypoxanthine-guanine phosphoribosyltransfe...   106   2e-21
ref|NP_001099141.1|  hypoxanthine phosphoribosyltransferase ...   105   2e-21
dbj|BAD43113.1|  putative hypoxanthine ribosyl transferase [...   105   2e-21
ref|YP_848383.1|  conserved hypothetical/hypoxanthine phosph...   105   2e-21
sp|P47959|HPRT_MERUN  Hypoxanthine-guanine phosphoribosyltra...   105   2e-21
ref|ZP_02618270.1|  hypoxanthine phosphoribosyltransferase [...   105   2e-21
ref|ZP_00741717.1|  Hypoxanthine-guanine phosphoribosyltrans...   105   2e-21
ref|XP_001625038.1|  predicted protein [Nematostella vectens...   105   2e-21
ref|XP_544231.2|  PREDICTED: similar to phosphoribosyl trans...   105   2e-21
ref|ZP_02581448.1|  hypoxanthine phosphoribosyltransferase [...   105   2e-21
ref|YP_001256007.1|  hypoxanthine phosphoribosyltransferase ...   105   2e-21
ref|ZP_02522268.1|  hypoxanthine-guanine phosphoribosyltrans...   105   2e-21
ref|ZP_04019022.1|  hypoxanthine phosphoribosyltransferase [...   105   2e-21
ref|NP_780915.1|  hypoxanthine-guanine phosphoribosyltransfe...   105   3e-21
ref|NP_720499.1|  hypoxanthine-guanine phosphoribosyltransfe...   105   3e-21
gb|AAF70286.1|AF254383_1  hypoxanthine phosphoribosyltransfe...   105   3e-21
ref|ZP_02525183.1|  hypoxanthine phosphoribosyltransferase [...   105   3e-21
ref|ZP_02081126.1|  hypothetical protein CLOLEP_02599 [Clost...   105   3e-21
ref|YP_002817623.1|  hypoxanthine phosphoribosyltransferase ...   105   3e-21
ref|YP_357955.1|  hypoxanthine phosphoribosyltransferase [Pe...   105   3e-21
ref|ZP_02278787.1|  hypothetical protein LmonF_02357 [Lister...   105   3e-21
ref|YP_001692114.1|  hypoxanthine-guanine phosphoribosyltran...   105   4e-21
ref|NP_964541.1|  hypoxanthine-guanine phosphoribosyltransfe...   105   4e-21
ref|YP_001678694.1|  hypoxanthine phosphoribosyltransferase ...   104   4e-21
emb|CAA35648.1|  hypoxanthine guanine phosphoribosyltransfer...   104   4e-21
ref|YP_001642956.1|  hypoxanthine phosphoribosyltransferase ...   104   4e-21
ref|YP_754454.1|  Hypoxanthine phosphoribosyltransferase [Sy...   104   4e-21
ref|XP_001371231.1|  PREDICTED: similar to hypoxanthine phos...   104   5e-21
ref|YP_001825599.1|  putative hypoxanthine phosphoribosyltra...   104   5e-21
ref|XP_001370978.1|  PREDICTED: similar to hypoxanthine phos...   104   5e-21
ref|YP_001708886.1|  putative hypoxanthine phosphoribosyltra...   104   5e-21
ref|NP_001027548.1|  hypoxanthine phosphoribosyltransferase ...   104   6e-21
ref|YP_001221583.1|  hypothetical protein CMM_0843 [Clavibac...   104   6e-21
gb|EEK06649.1|  hypoxanthine phosphoribosyltransferase [Brac...   104   6e-21
gb|EEJ98066.1|  hypoxanthine phosphoribosyltransferase [Ther...   104   7e-21
ref|NP_690999.1|  hypoxanthine phosphoribosyltransferase [Oc...   103   7e-21
ref|NP_842632.1|  hypoxanthine-guanine phosphoribosyltransfe...   103   7e-21
ref|XP_001371059.1|  PREDICTED: similar to hypoxanthine phos...   103   7e-21
ref|ZP_02263469.1|  hypoxanthine phosphoribosyltransferase [...   103   7e-21
ref|XP_001370603.1|  PREDICTED: similar to hypoxanthine phos...   103   8e-21
ref|ZP_03986123.1|  hypoxanthine phosphoribosyltransferase [...   103   8e-21
sp|P00494|HPRT_CRIGR  Hypoxanthine-guanine phosphoribosyltra...   103   9e-21
ref|YP_001414939.1|  hypoxanthine phosphoribosyltransferase ...   103   9e-21
ref|ZP_03951493.1|  hypoxanthine phosphoribosyltransferase [...   103   1e-20
ref|YP_001574409.1|  hypoxanthine phosphoribosyltransferase ...   103   1e-20
ref|YP_493197.1|  hypoxanthine phosphoribosyltransferase [St...   103   1e-20
ref|NP_240950.1|  hypoxanthine-guanine phosphoribosyltransfe...   103   1e-20
gb|EAY56375.1|  hypoxanthine-guanine phosphoribosyltransfera...   103   1e-20
ref|ZP_01313104.1|  hypoxanthine phosphoribosyltransferase [...   103   1e-20
ref|XP_001376250.1|  PREDICTED: similar to HHGP [Monodelphis...   103   1e-20
ref|NP_765828.1|  hypoxanthine-guanine phosphoribosyltransfe...   103   1e-20
ref|ZP_00530669.1|  Hypoxanthine phosphoribosyl transferase ...   103   1e-20
gb|ABI34109.1|  hypoxanthine phosphoribosyltransferase 1 [Xi...   103   1e-20
ref|XP_001371153.1|  PREDICTED: similar to hypoxanthine phos...   103   1e-20
ref|ZP_02078373.1|  hypothetical protein EUBDOL_02193 [Eubac...   102   2e-20
ref|ZP_01056939.1|  hypoxanthine phosphoribosyltransferase [...   102   2e-20
ref|NP_349799.1|  Hypoxanthine-guanine phosphoribosyltransfe...   102   2e-20
ref|NP_782785.1|  hypoxanthine-guanine phosphoribosyltransfe...   102   2e-20
ref|ZP_00994139.1|  putative hypoxanthine phosphoribosyltran...   102   2e-20
gb|AAB41678.1|  hypoxanthine-guanine phosphoribosyltransferase    102   2e-20
ref|NP_371034.1|  hypoxanthine-guanine phosphoribosyltransfe...   102   2e-20
ref|ZP_02951334.1|  hypoxanthine phosphoribosyltransferase [...   102   2e-20
ref|YP_001089202.1|  putative phosphoribosyltransferase [Clo...   102   2e-20
ref|ZP_02862733.1|  hypothetical protein ANASTE_01955 [Anaer...   102   2e-20
ref|YP_633224.1|  hypoxanthine phosphoribosyltransferase [My...   102   2e-20
ref|ZP_02143764.1|  hypoxanthine phosphoribosyltransferase [...   102   2e-20
ref|ZP_02148512.1|  hypoxanthine phosphoribosyltransferase [...   102   2e-20
ref|YP_682988.1|  hypoxanthine phosphoribosyltransferase [Ro...   102   3e-20
ref|ZP_02643856.1|  hypoxanthine phosphoribosyltransferase [...   102   3e-20
ref|YP_001331506.1|  hypoxanthine phosphoribosyltransferase ...   102   3e-20
ref|ZP_02169053.1|  Hypoxanthine phosphoribosyltransferase [...   102   3e-20
ref|NP_829966.1|  hypoxanthine-guanine phosphoribosyltransfe...   102   3e-20
ref|ZP_04021730.1|  hypoxanthine phosphoribosyltransferase [...   102   3e-20
ref|ZP_03882402.1|  hypoxanthine phosphoribosyltransferase [...   102   3e-20
ref|YP_814308.1|  Hypoxanthine-guanine phosphoribosyltransfe...   102   3e-20
ref|YP_001695855.1|  Hypoxanthine-guanine phosphoribosyltran...   102   3e-20
ref|ZP_01725398.1|  hypoxanthine-guanine phosphoribosyltrans...   102   3e-20
ref|NP_563387.1|  hypoxanthine-guanine phosphoribosyltransfe...   101   3e-20
ref|YP_001038649.1|  hypoxanthine phosphoribosyltransferase ...   101   4e-20
ref|ZP_02083316.1|  hypothetical protein CLOBOL_00837 [Clost...   101   4e-20
ref|ZP_01721183.1|  hypoxanthine-guanine phosphoribosyltrans...   101   4e-20
ref|YP_877129.1|  hypoxanthine phosphoribosyltransferase [Cl...   101   4e-20
ref|ZP_02991800.1|  hypoxanthine phosphoribosyltransferase [...   101   4e-20
ref|YP_912357.1|  hypoxanthine phosphoribosyltransferase [Ch...   101   4e-20
dbj|BAD93029.1|  phosphoribosyl transferase domain containin...   101   4e-20
ref|YP_001377333.1|  hypoxanthine phosphoribosyltransferase ...   101   4e-20
ref|ZP_01995978.1|  hypothetical protein DORLON_01976 [Dorea...   101   4e-20
ref|YP_001664305.1|  hypoxanthine phosphoribosyltransferase ...   101   4e-20
ref|XP_001156975.1|  PREDICTED: similar to Phosphoribosyl tr...   101   5e-20
gb|AAA93522.1|  hypoxanthine phosphoribosyltranserase             101   5e-20
ref|ZP_02177337.1|  hypoxanthine-guanine phosphoribosyltrans...   101   5e-20
ref|NP_064585.1|  phosphoribosyl transferase domain containi...   101   5e-20
ref|YP_001577509.1|  Hypoxanthine-guanine phosphoribosyltran...   101   5e-20
ref|YP_001360283.1|  hypoxanthine phosphoribosyltransferase ...   101   5e-20
emb|CAN75448.1|  hypothetical protein [Vitis vinifera] >gi|1...   101   5e-20
ref|XP_869469.1|  PREDICTED: similar to Hypoxanthine phospho...   101   5e-20
ref|YP_352844.1|  Hypoxanthine-guanine phosphoribosyltransfe...   101   5e-20
ref|XP_001101923.1|  PREDICTED: similar to phosphoribosyl tr...   101   5e-20
ref|ZP_03894492.1|  hypoxanthine phosphoribosyltransferase [...   101   5e-20
ref|YP_001274703.1|  hypoxanthine phosphoribosyltransferase ...   101   5e-20
ref|YP_001557268.1|  hypoxanthine phosphoribosyltransferase ...   100   6e-20
ref|NP_789114.1|  hypoxanthine phosphoribosyltransferase [Tr...   100   6e-20
ref|XP_638364.1|  hypoxanthine phosphoribosyltransferase [Di...   100   6e-20
ref|YP_697159.1|  hypoxanthine phosphoribosyltransferase [Cl...   100   6e-20
ref|NP_493545.1|  Y105E8B.5 [Caenorhabditis elegans] >gi|643...   100   7e-20
pdb|2JBH|A  Chain A, Human Phosphoribosyl Transferase Domain...   100   7e-20
ref|ZP_02943585.1|  hypoxanthine phosphoribosyltransferase [...   100   7e-20
ref|NP_787717.1|  hypoxanthine-guanine phosphoribosyltransfe...   100   7e-20
ref|YP_001430999.1|  hypoxanthine phosphoribosyltransferase ...   100   7e-20
dbj|BAD96394.1|  phosphoribosyl transferase domain containin...   100   7e-20
ref|ZP_01156250.1|  hypoxanthine phosphoribosyltransferase [...   100   7e-20
ref|ZP_02139177.1|  hypoxanthine phosphoribosyltransferase [...   100   7e-20
ref|ZP_01905974.1|  hypoxanthine-guanine phosphoribosyltrans...   100   8e-20
ref|XP_001470981.1|  hypoxanthine-guanine phosphoribosyltran...   100   8e-20
ref|ZP_01003606.1|  hypoxanthine phosphoribosyltransferase [...   100   9e-20
ref|YP_001618830.1|  Hypoxanthine-phosphoribosyltransferase ...   100   9e-20
>ref|XP_822397.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
 gb|EAN77569.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma brucei]
          Length = 234

 Score =  471 bits (1213), Expect = e-131,   Method: Composition-based stats.
 Identities = 234/234 (100%), Positives = 234/234 (100%)

Query: 1   MHSGHPLKPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKH 60
           MHSGHPLKPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKH
Sbjct: 1   MHSGHPLKPNFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKH 60

Query: 61  RDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGT 120
           RDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGT
Sbjct: 61  RDTHNKGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGT 120

Query: 121 TKSSGTVQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDK 180
           TKSSGTVQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDK
Sbjct: 121 TKSSGTVQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDK 180

Query: 181 PGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
           PGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL
Sbjct: 181 PGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
>ref|XP_813397.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi strain CL Brener]
 gb|EAN91546.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi]
          Length = 231

 Score =  298 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 138/223 (61%), Positives = 183/223 (82%), Gaps = 3/223 (1%)

Query: 12  VGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSAL 71
           V R+A+G + VDG++YPMAE +VATES I RS+K +A+ +A+ Y+ L HRDTH  G   +
Sbjct: 12  VSRNAEGVIVVDGKAYPMAEELVATESVIQRSIKAVAKQIADFYRPLSHRDTH--GGGGV 69

Query: 72  APITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLD 131
           API+DENPLIIISVLKGSYIFTADMVRYLGD GLP+VVDF+R+ SYRGT+ S+  +Q+L 
Sbjct: 70  APISDENPLIIISVLKGSYIFTADMVRYLGDYGLPHVVDFLRVASYRGTS-STNKMQLLA 128

Query: 132 NLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPE 191
             +F  L GKHVLI+EDI D+G+T++ +++K++RE++PA+LKVCVL DKPGGR V  +P+
Sbjct: 129 ETQFKALRGKHVLILEDIVDSGKTLRYILDKVQREHQPATLKVCVLADKPGGRRVTMQPD 188

Query: 192 FVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
           FVCLT P +YV+GYGFEVNDR+R +RH+F L+P  A+RYP+ L
Sbjct: 189 FVCLTVPNKYVIGYGFEVNDRFRCFRHIFTLRPGEARRYPAHL 231
>ref|XP_816917.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi strain CL Brener]
 gb|EAN95066.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi]
          Length = 231

 Score =  296 bits (757), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 137/223 (61%), Positives = 183/223 (82%), Gaps = 3/223 (1%)

Query: 12  VGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSAL 71
           V R+A+G + VDG++YPMAE +VATES I RS+K +A+ +A+ Y+ L HRDTH  G   +
Sbjct: 12  VSRNAEGVIVVDGKAYPMAEELVATESVIQRSIKAVAKQIADFYRPLSHRDTH--GGGGV 69

Query: 72  APITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLD 131
           API+DENPLIIISVLKGSYIFTADMVRYLGD GLP+VVDF+R+ SYRGT+ S+  +++L 
Sbjct: 70  APISDENPLIIISVLKGSYIFTADMVRYLGDYGLPHVVDFLRVASYRGTS-STNKMKLLA 128

Query: 132 NLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPE 191
             +F  L GKHVLI+EDI D+G+T++ +++K++RE++PA+LKVCVL DKPGGR V  +P+
Sbjct: 129 ETQFKALRGKHVLILEDIVDSGKTLRYILDKVQREHQPATLKVCVLADKPGGRRVTMQPD 188

Query: 192 FVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
           FVCLT P +YV+GYGFEVNDR+R +RH+F L+P  A+RYP+ L
Sbjct: 189 FVCLTVPNKYVIGYGFEVNDRFRCFRHIFTLRPGEARRYPAHL 231
>ref|XP_001564805.1| xanthine phosphoribosyltransferase [Leishmania braziliensis
           MHOM/BR/75/M2904]
 emb|CAM38880.1| xanthine phosphoribosyltransferase [Leishmania braziliensis]
          Length = 240

 Score =  263 bits (672), Expect = 7e-69,   Method: Composition-based stats.
 Identities = 128/229 (55%), Positives = 164/229 (71%), Gaps = 9/229 (3%)

Query: 15  DADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSAL--- 71
           DA G V VDGR YPMA S++ATE  I   +K MAQT+AN YK L HRD     N A    
Sbjct: 12  DAQGRVFVDGREYPMASSIIATEDVIQSKIKAMAQTIANDYKLLTHRDCRLPPNVATGME 71

Query: 72  -----APITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGT 126
                API+ +NPLII+SVLKGSYIFTAD +RYLGDCGLP+VVDF+R+TSY   T+S+G 
Sbjct: 72  TVVSEAPISYDNPLIIVSVLKGSYIFTADFIRYLGDCGLPHVVDFVRLTSYNDGTRSTGR 131

Query: 127 VQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDK-PGGRV 185
           V +L  L+F  L GKHVLI+ED+ D+GRT+  L   I  +Y+P S+K  V+V+K    R 
Sbjct: 132 VAMLSGLKFENLRGKHVLIVEDVCDSGRTLHFLRTSIIEKYQPKSIKTLVMVNKEAAARK 191

Query: 186 VDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
           VDF+PE+ CL++P +Y++GYGFEVNDRYR+ RH+ +L+   A RYP+KL
Sbjct: 192 VDFEPEYACLSSPNKYIIGYGFEVNDRYRDLRHILILRDGEATRYPAKL 240
>ref|XP_001683026.1| xanthine phosphoribosyltransferase [Leishmania major]
 emb|CAJ04332.1| xanthine phosphoribosyltransferase [Leishmania major]
          Length = 238

 Score =  254 bits (649), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 124/227 (54%), Positives = 161/227 (70%), Gaps = 7/227 (3%)

Query: 15  DADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTH------NKGN 68
           DA G V VDGR YPMA  +VATE  I  ++K MA T+A  YK+L HRD            
Sbjct: 12  DAQGRVFVDGREYPMASGIVATEDVIQANIKAMANTIAKDYKSLSHRDVRLSPGTAATAE 71

Query: 69  SALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQ 128
           +A API+ +NPLIIISVLKGSYIFT+D +RYLGDCGLP+VVDF+R+ SY   T S+G + 
Sbjct: 72  AAEAPISYDNPLIIISVLKGSYIFTSDFIRYLGDCGLPHVVDFVRLASYNSDTTSTGQIS 131

Query: 129 VLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKP-GGRVVD 187
           +L  LRF  L GKHVLI+ED+ D+GRT++ L + I  +++P S+K  V+V+K    R +D
Sbjct: 132 MLAGLRFENLRGKHVLIVEDVCDSGRTLRFLRDYIMEKFQPKSVKTLVMVNKEQAARKLD 191

Query: 188 FKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
           F PE+ CL  P +Y+VGYGFEVNDRYR+ RH+F+L+   A RYP+KL
Sbjct: 192 FDPEYFCLAGPNKYIVGYGFEVNDRYRDLRHIFILRDGEATRYPAKL 238
>gb|AAD50967.1|AF170105_2 xanthine phosphoribosyltransferase XPRT [Leishmania donovani]
          Length = 241

 Score =  254 bits (648), Expect = 4e-66,   Method: Composition-based stats.
 Identities = 125/230 (54%), Positives = 161/230 (70%), Gaps = 10/230 (4%)

Query: 15  DADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTH---------N 65
           DA G V VDGR YPMA  +VATE  I  ++K MA T+A  YK+L HRD            
Sbjct: 12  DAQGRVFVDGREYPMASGIVATEDVIQTNIKAMAHTIAKDYKSLSHRDARLSPSTAETAE 71

Query: 66  KGNSALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSG 125
              +A API+ +NPLIIISVLKGSYIFT+D +RYLGDCGLP+VVDF+R+ SY   TKS+G
Sbjct: 72  AAEAAEAPISYDNPLIIISVLKGSYIFTSDFIRYLGDCGLPHVVDFVRLASYNSGTKSTG 131

Query: 126 TVQVLDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKP-GGR 184
            + +L  LRF  L GKHVLI+ED+ D+GRT++ L + I  +++P S+K  V+V+K    R
Sbjct: 132 QISMLAGLRFENLRGKHVLIVEDVCDSGRTLRFLRDYIMEKFQPKSIKTLVMVNKEQAAR 191

Query: 185 VVDFKPEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
            VDF PE+ CL  P +Y+VGYGFEVNDRYR+ RH+ +L+   A RYP+KL
Sbjct: 192 KVDFDPEYFCLAGPNKYIVGYGFEVNDRYRDLRHILILRDGEATRYPAKL 241
>ref|XP_001463948.1| XRPT, xanthine phosphoribosyltransferase [Leishmania infantum
           JPCM5]
 emb|CAM66322.1| XRPT, xanthine phosphoribosyltransferase [Leishmania infantum]
          Length = 216

 Score =  233 bits (595), Expect = 6e-60,   Method: Composition-based stats.
 Identities = 115/216 (53%), Positives = 151/216 (69%), Gaps = 10/216 (4%)

Query: 29  MAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTH---------NKGNSALAPITDENP 79
           MA  +VATE  I  ++K MA T+A  YK+L HRD               +A API+ +NP
Sbjct: 1   MASGIVATEDVIQTNIKAMAHTIAKDYKSLSHRDARLSPSTAETAEAAEAAEAPISYDNP 60

Query: 80  LIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELT 139
           LIIISVLKGSYIFT+D +RYLGDCGLP+VVDF+R+ SY   TKS+G + +L  LRF  L 
Sbjct: 61  LIIISVLKGSYIFTSDFIRYLGDCGLPHVVDFVRLASYNSGTKSTGQISMLAGLRFENLR 120

Query: 140 GKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKP-GGRVVDFKPEFVCLTAP 198
           GKHVLI+ED+ D+GRT++ L + I  +++P S+K  V+V+K    R VDF PE+ CL  P
Sbjct: 121 GKHVLIVEDVCDSGRTLRFLRDYIMEKFQPKSIKTLVMVNKEQAARKVDFDPEYFCLAGP 180

Query: 199 TRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
            +Y+VGYGFEVNDRYR+ RH+ +L+   A RYP+KL
Sbjct: 181 NKYIVGYGFEVNDRYRDLRHILILRDGEATRYPAKL 216
>ref|XP_822398.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
 sp|Q07010|HPRT_TRYBB Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase)
 gb|AAA16328.1| hypoxanthine-guanine phosphoribosyltransferase
 gb|EAN77570.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
          Length = 210

 Score =  161 bits (408), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 91/209 (43%), Positives = 129/209 (61%), Gaps = 17/209 (8%)

Query: 27  YPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVL 86
           Y  A SV+ TE+ +H  M+ +AQ +A+ Y            N  L P+  ENPL+I+SVL
Sbjct: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYS-----------NCNLKPL--ENPLVIVSVL 53

Query: 87  KGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQV-LDNLRFTELTGKHVLI 145
           KGS++FTADMVR LGD G+P  V+F+R +SY   TKS G V V  D L   ++ GKHVL+
Sbjct: 54  KGSFVFTADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGL--CDIRGKHVLV 111

Query: 146 MEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGY 205
           +EDI DT  T++ +V+ +++   PAS+K  V +DKPGGR + F  E+V    P  +VVGY
Sbjct: 112 LEDILDTALTLREVVDSLKKS-EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGY 170

Query: 206 GFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
           G + +  YR  R V +LKP   + +  +L
Sbjct: 171 GLDYDQSYREVRDVVILKPSVYETWGKEL 199
>ref|XP_822405.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
 gb|EAN77577.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
          Length = 210

 Score =  159 bits (403), Expect = 1e-37,   Method: Composition-based stats.
 Identities = 89/209 (42%), Positives = 129/209 (61%), Gaps = 17/209 (8%)

Query: 27  YPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVL 86
           Y  A SV+ TE+ +H  M+ +AQ +A+ Y            N  L P+  ENPL+++SVL
Sbjct: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYS-----------NCNLKPL--ENPLVVVSVL 53

Query: 87  KGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQV-LDNLRFTELTGKHVLI 145
           +GS++FTADMVR LGD G+P  V+F+R +SY   TKS G V V  D L   ++ GKHVL+
Sbjct: 54  RGSFVFTADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGL--CDIRGKHVLV 111

Query: 146 MEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGY 205
           +EDI DT  T++ +V+ +++   PAS+K  V +DKPGGR + F  E+V    P  +VVGY
Sbjct: 112 LEDILDTALTLREVVDSLKKS-EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGY 170

Query: 206 GFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
           G + +  YR  R V +LKP   + +  +L
Sbjct: 171 GLDYDQSYREVRDVVILKPSVYETWGKEL 199
>sp|Q27541|HPRT_CRIFA Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase)
 gb|AAB04164.1| hypoxanthine-guanine phophoribosyltransferase
          Length = 208

 Score =  141 bits (356), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 80/210 (38%), Positives = 125/210 (59%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R YPM+   +AT+  I  +  + A+ +A  YK                 ++DENPL ++ 
Sbjct: 15  RHYPMSCRTLATQEQIWSATAKCAKQIAEDYKQYN--------------LSDENPLYLLC 60

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS++FTAD+ R+L D G+P  ++FI  +SY    K+SG V++L ++R   +  +H+L
Sbjct: 61  VLKGSFMFTADLARFLCDEGVPVRIEFICASSYGTDVKTSGEVRLLLDVR-DPVENRHLL 119

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI D+  T++ L ++  +  +PASLK  VL+DKP GR V    ++  +T P  +V+G
Sbjct: 120 IVEDIVDSAITLEYL-KRFLQAKQPASLKTVVLLDKPSGRKVTLSVDYPVITIPHAFVIG 178

Query: 205 YGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
           YG +  + YR  R V VLK EY ++  SKL
Sbjct: 179 YGMDFAEAYRELRDVCVLKKEYYEKPASKL 208
>ref|XP_816916.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi strain CL Brener]
 gb|EAN95065.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi]
          Length = 241

 Score =  140 bits (352), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 86/210 (40%), Positives = 123/210 (58%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R Y  AE ++ TE  I   +KE+A+ +A+ YK              L P    NPL++IS
Sbjct: 23  REYEFAEKILFTEEEIRTRIKEVAKRIADDYK-----------GKGLRPYV--NPLVLIS 69

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS++FTAD+ R L D  +P  ++FI ++SY     SSG V++L + R + + G HVL
Sbjct: 70  VLKGSFMFTADLCRALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHS-IEGHHVL 128

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI DT  T+  L   +    RPASLK  VL+DK  GR V F  ++V    P  +V+G
Sbjct: 129 IVEDIVDTALTLNYLYH-MYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIG 187

Query: 205 YGFEVNDRYRNYRHVFVLKPE-YAKRYPSK 233
           YG + +D YR  R + VL+PE YA+R  ++
Sbjct: 188 YGLDYDDTYRELRDIVVLRPEVYAEREAAR 217
>pdb|1PZM|A Chain A, Crystal Structure Of Hgprt-Ase From Leishmania Tarentolae
           In Complex With Gmp
 pdb|1PZM|B Chain B, Crystal Structure Of Hgprt-Ase From Leishmania Tarentolae
           In Complex With Gmp
          Length = 211

 Score =  139 bits (351), Expect = 1e-31,   Method: Composition-based stats.
 Identities = 82/225 (36%), Positives = 131/225 (58%), Gaps = 16/225 (7%)

Query: 10  NFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNS 69
           N V   +D    V  R+YPM+   + T+  +  +  + A+ +A  YK     D H     
Sbjct: 3   NSVKSPSDHVGDVGRRNYPMSARTLVTQEQVWAATAKCAKKIAADYK-----DFH----- 52

Query: 70  ALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQV 129
               +T +NPL ++ VLKGS+IFTAD+ R+L D G+P  V+FI  +SY    ++SG V++
Sbjct: 53  ----LTADNPLYLLCVLKGSFIFTADLARFLADEGVPVKVEFICASSYGSGVETSGQVRM 108

Query: 130 LDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFK 189
           L ++R   +  +H++++EDI D+  T++ L+ +     +PASLK  VL+DKP GR VD  
Sbjct: 109 LLDVR-DSVENRHIMLVEDIVDSAITLQYLM-RFMLAKKPASLKTVVLLDKPSGRKVDVL 166

Query: 190 PEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
            ++  +T P  +V+GYG +  + YR  R + VLK EY ++  SKL
Sbjct: 167 VDYPVITIPRAFVIGYGMDFAESYRELRDICVLKKEYYEKAESKL 211
>pdb|1TC2|A Chain A, Ternary Substrate Complex Of The Hypoxanthine
           Phosphoribosyltransferase From Trypanosoma Cruzi
 pdb|1TC2|B Chain B, Ternary Substrate Complex Of The Hypoxanthine
           Phosphoribosyltransferase From Trypanosoma Cruzi
 pdb|1P19|A Chain A, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
 pdb|1P19|B Chain B, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
 pdb|1P19|C Chain C, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
 pdb|1P19|D Chain D, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
          Length = 221

 Score =  139 bits (350), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 86/210 (40%), Positives = 123/210 (58%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R Y  AE ++ TE  I   +KE+A+ +A+ YK              L P    NPL++IS
Sbjct: 3   REYEFAEKILFTEEEIRTRIKEVAKRIADDYK-----------GKGLRPYV--NPLVLIS 49

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS++FTAD+ R L D  +P  ++FI ++SY     SSG V++L + R + + G HVL
Sbjct: 50  VLKGSFMFTADLCRALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHS-IEGHHVL 108

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI DT  T+  L   +    RPASLK  VL+DK  GR V F  ++V    P  +V+G
Sbjct: 109 IVEDIVDTALTLNYLYH-MYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIG 167

Query: 205 YGFEVNDRYRNYRHVFVLKPE-YAKRYPSK 233
           YG + +D YR  R + VL+PE YA+R  ++
Sbjct: 168 YGLDYDDTYRELRDIVVLRPEVYAEREAAR 197
>pdb|1TC1|A Chain A, A 1.4 Angstrom Crystal Structure For The Hypoxanthine
           Phosphoribosyltransferase Of Trypanosoma Cruzi
 pdb|1TC1|B Chain B, A 1.4 Angstrom Crystal Structure For The Hypoxanthine
           Phosphoribosyltransferase Of Trypanosoma Cruzi
          Length = 220

 Score =  139 bits (349), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 86/210 (40%), Positives = 123/210 (58%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R Y  AE ++ TE  I   +KE+A+ +A+ YK              L P    NPL++IS
Sbjct: 2   REYEFAEKILFTEEEIRTRIKEVAKRIADDYK-----------GKGLRPYV--NPLVLIS 48

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS++FTAD+ R L D  +P  ++FI ++SY     SSG V++L + R + + G HVL
Sbjct: 49  VLKGSFMFTADLCRALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHS-IEGHHVL 107

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI DT  T+  L   +    RPASLK  VL+DK  GR V F  ++V    P  +V+G
Sbjct: 108 IVEDIVDTALTLNYLYH-MYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIG 166

Query: 205 YGFEVNDRYRNYRHVFVLKPE-YAKRYPSK 233
           YG + +D YR  R + VL+PE YA+R  ++
Sbjct: 167 YGLDYDDTYRELRDIVVLRPEVYAEREAAR 196
>ref|XP_001463947.1| HGPRT,hypoxanthine-guanine phosphoribosynthesis protein [Leishmania
           infantum JPCM5]
 sp|P43152|HPRT_LEIDO Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase)
 gb|AAD50966.1|AF170105_1 hypoxanthine-guanine phosphoribosyltransferase HGPRT [Leishmania
           donovani]
 gb|AAB00074.1| hypoxanthine-guanine phosphoribosyltransferase
 emb|CAM66321.1| HGPRT,hypoxanthine-guanine phosphoribosynthesis protein [Leishmania
           infantum]
          Length = 211

 Score =  138 bits (347), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 76/210 (36%), Positives = 126/210 (60%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R+YPM+   + T+  +  +  + A+ +A  Y++ K              +T +NPL ++ 
Sbjct: 18  RNYPMSAHTLVTQEQVWAATAKCAKKIAEDYRSFK--------------LTTDNPLYLLC 63

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS+IFTAD+ R+L D G+P  V+FI  +SY    ++SG V++L ++R   +  +H+L
Sbjct: 64  VLKGSFIFTADLARFLADEGVPVKVEFICASSYGTGVETSGQVRMLLDVR-DSVENRHIL 122

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI D+  T++ L+ +     +PASLK  VL+DKP GR V+   ++  +T P  +V+G
Sbjct: 123 IVEDIVDSAITLQYLM-RFMLAKKPASLKTVVLLDKPSGRKVEVLVDYPVITIPHAFVIG 181

Query: 205 YGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
           YG +  + YR  R + VLK EY ++  SK+
Sbjct: 182 YGMDYAESYRELRDICVLKKEYYEKPESKV 211
>pdb|1P17|A Chain A, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P17|B Chain B, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P17|C Chain C, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P17|D Chain D, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P18|A Chain A, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Ternary Substrates Complex
 pdb|1P18|B Chain B, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Ternary Substrates Complex
          Length = 221

 Score =  138 bits (347), Expect = 4e-31,   Method: Composition-based stats.
 Identities = 85/210 (40%), Positives = 123/210 (58%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R Y  AE ++ TE  I   +KE+A+ +A+ YK              L P    NPL++IS
Sbjct: 3   REYEFAEKILFTEEEIRTRIKEVAKRIADDYK-----------GKGLRPYV--NPLVLIS 49

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VL+GS++FTAD+ R L D  +P  ++FI ++SY     SSG V++L + R + + G HVL
Sbjct: 50  VLRGSFMFTADLCRALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHS-IEGHHVL 108

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI DT  T+  L   +    RPASLK  VL+DK  GR V F  ++V    P  +V+G
Sbjct: 109 IVEDIVDTALTLNYLYH-MYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIG 167

Query: 205 YGFEVNDRYRNYRHVFVLKPE-YAKRYPSK 233
           YG + +D YR  R + VL+PE YA+R  ++
Sbjct: 168 YGLDYDDTYRELRDIVVLRPEVYAEREAAR 197
>pdb|1I14|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamic
           Acid Mutant
 pdb|1I14|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamic
           Acid Mutant
          Length = 221

 Score =  137 bits (345), Expect = 6e-31,   Method: Composition-based stats.
 Identities = 85/210 (40%), Positives = 123/210 (58%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R Y  AE ++ TE  I   +KE+A+ +A+ YK              L P    NPL++IS
Sbjct: 3   REYEFAEKILFTEEEIRTRIKEVAKRIADDYK-----------GKGLRPYV--NPLVLIS 49

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS++FTAD+ R L D  +P  ++FI ++SY     SSG V++L + R + + G HVL
Sbjct: 50  VLKGSFMFTADLCRALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHS-IEGHHVL 108

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI +T  T+  L   +    RPASLK  VL+DK  GR V F  ++V    P  +V+G
Sbjct: 109 IVEDIVETALTLNYLYH-MYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIG 167

Query: 205 YGFEVNDRYRNYRHVFVLKPE-YAKRYPSK 233
           YG + +D YR  R + VL+PE YA+R  ++
Sbjct: 168 YGLDYDDTYRELRDIVVLRPEVYAEREAAR 197
>ref|XP_813396.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi strain CL Brener]
 gb|AAB46391.1| hypoxanthine-guanine phosphoribosyltransferase
 gb|EAN91545.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi]
          Length = 221

 Score =  137 bits (345), Expect = 6e-31,   Method: Composition-based stats.
 Identities = 85/210 (40%), Positives = 122/210 (58%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R Y  AE ++ TE  I   + E+A+ +A+ YK              L P    NPL++IS
Sbjct: 3   REYEFAEKILFTEEEIRTRIMEVAKRIADDYK-----------GKGLRPYV--NPLVLIS 49

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS++FTAD+ R L D  +P  ++FI ++SY     SSG V++L + R + + G HVL
Sbjct: 50  VLKGSFMFTADLCRALSDFNVPVRMEFICVSSYGEGVTSSGQVRMLLDTRHS-IEGHHVL 108

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI DT  T+  L   +    RPASLK  VL+DK  GR V F  ++V    P  +V+G
Sbjct: 109 IVEDIVDTALTLNYLYH-MYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIG 167

Query: 205 YGFEVNDRYRNYRHVFVLKPE-YAKRYPSK 233
           YG + +D YR  R + VL+PE YA+R  ++
Sbjct: 168 YGLDYDDTYRELRDIVVLRPEVYAEREAAR 197
>pdb|1I0L|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Asparagine
           Mutant
 pdb|1I0L|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Asparagine
           Mutant
          Length = 221

 Score =  137 bits (345), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 85/210 (40%), Positives = 123/210 (58%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R Y  AE ++ TE  I   +KE+A+ +A+ YK              L P    NPL++IS
Sbjct: 3   REYEFAEKILFTEEEIRTRIKEVAKRIADDYK-----------GKGLRPYV--NPLVLIS 49

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS++FTAD+ R L D  +P  ++FI ++SY     SSG V++L + R + + G HVL
Sbjct: 50  VLKGSFMFTADLCRALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHS-IEGHHVL 108

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI +T  T+  L   +    RPASLK  VL+DK  GR V F  ++V    P  +V+G
Sbjct: 109 IVEDIVNTALTLNYLYH-MYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIG 167

Query: 205 YGFEVNDRYRNYRHVFVLKPE-YAKRYPSK 233
           YG + +D YR  R + VL+PE YA+R  ++
Sbjct: 168 YGLDYDDTYRELRDIVVLRPEVYAEREAAR 197
>ref|XP_001564804.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania
           braziliensis MHOM/BR/75/M2904]
 emb|CAM38879.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania
           braziliensis]
          Length = 211

 Score =  137 bits (345), Expect = 7e-31,   Method: Composition-based stats.
 Identities = 82/210 (39%), Positives = 122/210 (58%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           RSYPM+   V T+  +  +  + A+T+A  Y+  K           LAP   ENPL ++ 
Sbjct: 18  RSYPMSARTVITQEQVWAATAQCAKTIAQDYEKFK-----------LAP---ENPLYLLC 63

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS+IFTAD+ R+L D G+P  V+FI  +SY    ++SG V++L ++R   +  +H+L
Sbjct: 64  VLKGSFIFTADLARFLADEGVPVRVEFICASSYGEGVETSGQVRMLLDVR-DSVEDRHIL 122

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI D+  T++ L+ +     RPASLK  VL+DKP  R V    ++  +  P  +V+G
Sbjct: 123 IVEDIVDSAITLQYLM-RFMLAKRPASLKTVVLLDKPSRRKVKLLVDYPIIRVPDVFVIG 181

Query: 205 YGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
           YG +  + YR  R V  LK EY  +  SKL
Sbjct: 182 YGMDFAESYRELRDVCELKKEYYLKPTSKL 211
>ref|XP_001683025.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania major]
 emb|CAJ04328.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania major]
          Length = 211

 Score =  137 bits (344), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 76/210 (36%), Positives = 125/210 (59%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R+YPM+   + T+  +  +  + A+ +A  Y++ K              +T  NPL ++ 
Sbjct: 18  RNYPMSAHTLVTQEQVWAATAKCAKKIAEDYRSFK--------------LTTGNPLYLLC 63

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS+IFTAD+ R+L D G+P  V+FI  +SY    ++SG V++L ++R   +  +H+L
Sbjct: 64  VLKGSFIFTADLARFLADEGVPVKVEFICASSYGTGVETSGQVRMLLDVR-DSVENRHIL 122

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI D+  T++ L+ +     +PASLK  VL+DKP GR V+   ++  +T P  +V+G
Sbjct: 123 IVEDIVDSAITLQYLM-RFMLAKKPASLKTVVLLDKPSGRKVEVLVDYPVITIPHAFVIG 181

Query: 205 YGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
           YG +  + YR  R + VLK EY ++  SK+
Sbjct: 182 YGMDYAESYRELRDICVLKKEYYEKPESKV 211
>pdb|1I0I|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamine
           Mutant
 pdb|1I0I|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamine
           Mutant
          Length = 221

 Score =  136 bits (343), Expect = 9e-31,   Method: Composition-based stats.
 Identities = 85/210 (40%), Positives = 122/210 (58%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R Y  AE ++ TE  I   +KE+A+ +A+ YK              L P    NPL++IS
Sbjct: 3   REYEFAEKILFTEEEIRTRIKEVAKRIADDYK-----------GKGLRPYV--NPLVLIS 49

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS++FTAD+ R L D  +P  ++FI ++SY     SSG V++L + R + + G HVL
Sbjct: 50  VLKGSFMFTADLCRALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHS-IEGHHVL 108

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI  T  T+  L   +    RPASLK  VL+DK  GR V F  ++V    P  +V+G
Sbjct: 109 IVEDIVQTALTLNYLYH-MYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIG 167

Query: 205 YGFEVNDRYRNYRHVFVLKPE-YAKRYPSK 233
           YG + +D YR  R + VL+PE YA+R  ++
Sbjct: 168 YGLDYDDTYRELRDIVVLRPEVYAEREAAR 197
>pdb|1I13|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Alanine
           Mutant
 pdb|1I13|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Alanine
           Mutant
          Length = 221

 Score =  136 bits (342), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 85/210 (40%), Positives = 122/210 (58%), Gaps = 16/210 (7%)

Query: 25  RSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIIS 84
           R Y  AE ++ TE  I   +KE+A+ +A+ YK              L P    NPL++IS
Sbjct: 3   REYEFAEKILFTEEEIRTRIKEVAKRIADDYK-----------GKGLRPYV--NPLVLIS 49

Query: 85  VLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVL 144
           VLKGS++FTAD+ R L D  +P  ++FI ++SY     SSG V++L + R + + G HVL
Sbjct: 50  VLKGSFMFTADLCRALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHS-IEGHHVL 108

Query: 145 IMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVG 204
           I+EDI  T  T+  L   +    RPASLK  VL+DK  GR V F  ++V    P  +V+G
Sbjct: 109 IVEDIVATALTLNYLYH-MYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIG 167

Query: 205 YGFEVNDRYRNYRHVFVLKPE-YAKRYPSK 233
           YG + +D YR  R + VL+PE YA+R  ++
Sbjct: 168 YGLDYDDTYRELRDIVVLRPEVYAEREAAR 197
>ref|YP_794711.1| Hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus
           brevis ATCC 367]
 gb|ABJ63680.1| hypoxanthine phosphoribosyltransferase [Lactobacillus brevis ATCC
           367]
          Length = 180

 Score =  131 bits (329), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 75/194 (38%), Positives = 118/194 (60%), Gaps = 25/194 (12%)

Query: 31  ESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSY 90
           E V+ +E  I  + K + Q LA  Y+                   D+ PL++  VLKG+ 
Sbjct: 6   EKVLYSEEDIAAACKRLGQQLAEDYR-------------------DKTPLMV-CVLKGAI 45

Query: 91  IFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIA 150
           +F  D++R   D  +   +DFI ++SY G T+SSGT+++L +L  T++ G+ V+++EDI 
Sbjct: 46  LFMTDVIR---DMDIYATIDFIDVSSYNGGTESSGTIRLLKDLD-TDVAGRDVVLVEDII 101

Query: 151 DTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVN 210
           DTGRT+K L E + ++ +  S+KVC L+DKP GRVV+ K ++V    P+ +VVGYG +  
Sbjct: 102 DTGRTLKYL-EDLLKDRQAKSIKVCTLMDKPSGRVVEAKADYVGFNVPSEFVVGYGLDYE 160

Query: 211 DRYRNYRHVFVLKP 224
           ++YRN  +V VLKP
Sbjct: 161 EKYRNLPYVGVLKP 174
>ref|YP_001916267.1| hypoxanthine phosphoribosyltransferase [Natranaerobius thermophilus
           JW/NM-WN-LF]
 gb|ACB83679.1| hypoxanthine phosphoribosyltransferase [Natranaerobius thermophilus
           JW/NM-WN-LF]
          Length = 181

 Score =  130 bits (328), Expect = 6e-29,   Method: Composition-based stats.
 Identities = 64/146 (43%), Positives = 98/146 (67%), Gaps = 5/146 (3%)

Query: 80  LIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELT 139
           +I + VLKGS++F AD++R L    +PN +DF+ ++SY  +TKSSG +++L +L  T + 
Sbjct: 39  VIAVGVLKGSFVFAADLLRQLS---IPNEIDFLAVSSYGASTKSSGIIRILKDLD-TSIE 94

Query: 140 GKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPT 199
            KHVLI+EDI DTG T+  L+E +    +PASLK+C L+DKP  R VD  P+++    P 
Sbjct: 95  NKHVLIVEDIVDTGLTLNYLLETLSTR-KPASLKICTLLDKPDRREVDLTPDYIGFQIPD 153

Query: 200 RYVVGYGFEVNDRYRNYRHVFVLKPE 225
            +VVGYG +  + YR++  ++VL  E
Sbjct: 154 LFVVGYGLDYAEYYRDWPAIYVLPEE 179
>gb|AAF61462.1|AF139722_1 hypoxanthine-guanine phosphoribosyltransferase; HGPRT [Leishmania
           tarentolae]
          Length = 210

 Score =  127 bits (319), Expect = 7e-28,   Method: Composition-based stats.
 Identities = 80/225 (35%), Positives = 128/225 (56%), Gaps = 17/225 (7%)

Query: 10  NFVGRDADGNVTVDGRSYPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNS 69
           N V   +D    V  R+YPM+   + T+  +  +  + A+ +A  YK     D H     
Sbjct: 3   NSVKSPSDHVGDVGRRNYPMSARTLVTQEQVWAATAKCAKKIAADYK-----DFH----- 52

Query: 70  ALAPITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQV 129
               +T +NPL ++ VLKGS+IFTAD+ R+L D G+P  V+FI  +SY    ++SG V++
Sbjct: 53  ----LTADNPLYLLCVLKGSFIFTADLARFLADEGVPVKVEFICASSYGSGVETSGQVRM 108

Query: 130 LDNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFK 189
           L ++R   +  +H++++EDI D+  T++ L+ +     +PASLK  VL+DKP GR VD  
Sbjct: 109 LLDVR-DSVENRHIMLVEDIVDSAITLQYLM-RFMLAKKPASLKTVVLLDKPSGRKVDVL 166

Query: 190 PEFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
            ++  +T P  +V+GY +   D  R    + VLK EY ++  SKL
Sbjct: 167 VDYPVITIPHAFVIGYVWTFAD-LRGVPDICVLKKEYYEKAESKL 210
>ref|NP_784322.1| hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus
           plantarum WCFS1]
 emb|CAD63163.1| hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus
           plantarum WCFS1]
          Length = 180

 Score =  127 bits (318), Expect = 9e-28,   Method: Composition-based stats.
 Identities = 74/194 (38%), Positives = 114/194 (58%), Gaps = 25/194 (12%)

Query: 31  ESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSY 90
           E V+ +   IH+  +++ + L  AY                     +NPLII  VLKG+ 
Sbjct: 6   ERVLYSREDIHQVAQKLGKELTTAY-------------------AGKNPLII-CVLKGAV 45

Query: 91  IFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIA 150
           +FT D++R   +  +   +DFI ++SY   T SSG VQ+  +L   ++TG+ VL++EDI 
Sbjct: 46  LFTTDIIR---EMDIYADLDFINLSSYGNETISSGEVQLTKDLD-ADVTGRDVLVIEDII 101

Query: 151 DTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVN 210
           DTGRT+K L++ ++R     S+KVC L+DKP GR+VD K +++    P  +VVGYG +  
Sbjct: 102 DTGRTLKFLIDLLKRR-DVNSVKVCTLLDKPAGRLVDIKADYIGFEVPNEFVVGYGLDYA 160

Query: 211 DRYRNYRHVFVLKP 224
           +RYRN  +V +LKP
Sbjct: 161 ERYRNLPYVGILKP 174
>ref|YP_001113711.1| hypoxanthine phosphoribosyltransferase [Desulfotomaculum reducens
           MI-1]
 gb|ABO50886.1| hypoxanthine phosphoribosyltransferase [Desulfotomaculum reducens
           MI-1]
          Length = 179

 Score =  125 bits (313), Expect = 3e-27,   Method: Composition-based stats.
 Identities = 68/199 (34%), Positives = 113/199 (56%), Gaps = 25/199 (12%)

Query: 27  YPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVL 86
           +P  E ++  E+ I+  ++++ Q +   Y+                       ++++ +L
Sbjct: 2   HPHVEKILLEENQINERIQQLGQQITQDYQG--------------------KDILMVGIL 41

Query: 87  KGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIM 146
           KG+ IF AD+VR   +  +P   DF+ ++SY   T SSG V++L +L    + GKH++I+
Sbjct: 42  KGAMIFLADLVR---NIEVPTFFDFMAVSSYGAGTVSSGVVRILKDLD-KSIEGKHIIIV 97

Query: 147 EDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYG 206
           EDI DTG T++ +VE I+    PAS+KVC L+DKP  R V+   ++     P  +VVG+G
Sbjct: 98  EDIVDTGLTLQYMVENIKSR-GPASVKVCTLLDKPDRRKVEVPIDYNGFQIPDEFVVGFG 156

Query: 207 FEVNDRYRNYRHVFVLKPE 225
            + N+RYRN  ++ VLKPE
Sbjct: 157 LDYNERYRNLPYIAVLKPE 175
>ref|YP_001512894.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus oremlandii
           OhILAs]
 gb|ABW18898.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus oremlandii
           OhILAs]
          Length = 180

 Score =  124 bits (312), Expect = 4e-27,   Method: Composition-based stats.
 Identities = 71/199 (35%), Positives = 116/199 (58%), Gaps = 24/199 (12%)

Query: 27  YPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVL 86
           Y   E V+ ++  I + +KE+ + ++  YK                   + + L+II VL
Sbjct: 2   YNDVEEVLFSKEDIAKKVKELGEIISKDYK-------------------ENDDLVIIGVL 42

Query: 87  KGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIM 146
           KG+ +F AD++R   +  +P  +DF+ ++SY  +T+SSG V++L +L   E+ GKHVLI+
Sbjct: 43  KGANVFMADLMR---EITIPVYIDFMAVSSYGYSTESSGIVRILKDLDL-EIEGKHVLII 98

Query: 147 EDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYG 206
           EDI DTG T+K L + ++      S+K+C L+DKP  R  D K +++    P +++VGYG
Sbjct: 99  EDIIDTGLTLKYLTDNLKSR-NTKSVKICTLLDKPVRRKCDLKVDYMGFEIPDKFIVGYG 157

Query: 207 FEVNDRYRNYRHVFVLKPE 225
            +  +RYRN  +V  LKPE
Sbjct: 158 IDYGERYRNLPYVASLKPE 176
>gb|ABE47510.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania
           infantum]
          Length = 168

 Score =  124 bits (311), Expect = 5e-27,   Method: Composition-based stats.
 Identities = 65/153 (42%), Positives = 101/153 (66%), Gaps = 2/153 (1%)

Query: 74  ITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNL 133
           +T +NPL ++ VLKGS+IFTAD+ R+L D G+P  V+FI  +SY    ++SG V++L ++
Sbjct: 18  LTTDNPLYLLCVLKGSFIFTADLARFLADEGVPVKVEFICASSYGTGVETSGQVRMLLDV 77

Query: 134 RFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFV 193
           R   +  +H+LI+EDI D+  T++ L+ +     +PASLK  VL+DKP GR V+   ++ 
Sbjct: 78  R-DSVENRHILIVEDIVDSAITLQYLM-RFMLAKKPASLKTVVLLDKPSGRKVEVLVDYP 135

Query: 194 CLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEY 226
            +T P  +V+GYG +  + YR  R + VLK EY
Sbjct: 136 VITIPHAFVIGYGMDYAESYRELRDICVLKKEY 168
>ref|YP_001319457.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus
           metalliredigens QYMF]
 gb|ABR47798.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus
           metalliredigens QYMF]
          Length = 179

 Score =  124 bits (310), Expect = 6e-27,   Method: Composition-based stats.
 Identities = 72/190 (37%), Positives = 114/190 (60%), Gaps = 25/190 (13%)

Query: 33  VVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIF 92
           V+ +E  I   +KE+ + L+  YK  K                    L +IS+LKGS++F
Sbjct: 10  VLCSEEDIENRLKELGEQLSIEYKGKK--------------------LYVISLLKGSFVF 49

Query: 93  TADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIADT 152
           TAD+VR L    +P  ++F+  +SY    KSSG V+++ +++  +LTG  VL+ +DI D+
Sbjct: 50  TADLVRQLT---IPVKINFMTTSSYGHDEKSSGHVKIVTDVQ-EDLTGYDVLVADDITDS 105

Query: 153 GRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDR 212
           G TMK +++ ++ +  P+S+K CVL+DKP  R VD +P++V  T P ++VVGYG    D 
Sbjct: 106 GLTMKEVMDHLKSK-NPSSVKSCVLLDKPDRRKVDLEPDYVGFTIPDKFVVGYGLNFGDY 164

Query: 213 YRNYRHVFVL 222
           YRN  +VFV+
Sbjct: 165 YRNIPYVFVV 174
>ref|YP_002769603.1| hypoxanthine-guanine phosphoribosyltransferase [Brevibacillus
           brevis NBRC 100599]
 dbj|BAH41099.1| hypoxanthine-guanine phosphoribosyltransferase [Brevibacillus
           brevis NBRC 100599]
          Length = 179

 Score =  124 bits (310), Expect = 7e-27,   Method: Composition-based stats.
 Identities = 74/195 (37%), Positives = 114/195 (58%), Gaps = 25/195 (12%)

Query: 31  ESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSY 90
           E ++ +E  I   ++E+ +TLA  YK                   D+NPL+I  VLKG+ 
Sbjct: 6   EKILLSEEDIAGKVRELGETLAAEYK-------------------DKNPLVI-CVLKGAV 45

Query: 91  IFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIA 150
           IF AD++R++    +P  +DF+ ++SY   T+SSG V++L +L  T +  +HVL++EDI 
Sbjct: 46  IFMADLIRHMS---IPCEMDFMAVSSYGSGTESSGMVKILKDLD-TSVENRHVLVVEDIM 101

Query: 151 DTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVN 210
           D+G T+  LVE +R     AS+KV  L++KP  R VD  P++     P  +VVGYG +  
Sbjct: 102 DSGLTLSRLVELLRHR-EAASVKVVTLLNKPERRKVDISPDYKGYDVPDEFVVGYGLDYA 160

Query: 211 DRYRNYRHVFVLKPE 225
           + YRN  ++ VLKPE
Sbjct: 161 EHYRNLPYIGVLKPE 175
>gb|ABE47508.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania sp.
           IMT208]
          Length = 168

 Score =  123 bits (309), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 65/153 (42%), Positives = 100/153 (65%), Gaps = 2/153 (1%)

Query: 74  ITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNL 133
           +T  NPL ++ VLKGS+IFTAD+ R+L D G+P  V+FI  +SY    ++SG V++L ++
Sbjct: 18  LTTXNPLYLLCVLKGSFIFTADLARFLADEGVPVKVEFICASSYGTGVETSGQVRMLLDV 77

Query: 134 RFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFV 193
           R   +  +H+LI+EDI D+  T++ L+ +     +PASLK  VL+DKP GR V+   ++ 
Sbjct: 78  R-DSVENRHILIVEDIVDSAITLQYLM-RFMLAKKPASLKTVVLLDKPSGRKVEVLVDYP 135

Query: 194 CLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEY 226
            +T P  +V+GYG +  + YR  R + VLK EY
Sbjct: 136 VITIPHAFVIGYGMDYAESYRELRDICVLKKEY 168
>gb|ABE47509.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania major]
          Length = 168

 Score =  123 bits (308), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 65/153 (42%), Positives = 100/153 (65%), Gaps = 2/153 (1%)

Query: 74  ITDENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNL 133
           +T  NPL ++ VLKGS+IFTAD+ R+L D G+P  V+FI  +SY    ++SG V++L ++
Sbjct: 18  LTTGNPLYLLCVLKGSFIFTADLARFLADEGVPVKVEFICASSYGTGVETSGQVRMLLDV 77

Query: 134 RFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFV 193
           R   +  +H+LI+EDI D+  T++ L+ +     +PASLK  VL+DKP GR V+   ++ 
Sbjct: 78  R-DSVENRHILIVEDIVDSAITLQYLM-RFMLAKKPASLKTVVLLDKPSGRKVEVLVDYP 135

Query: 194 CLTAPTRYVVGYGFEVNDRYRNYRHVFVLKPEY 226
            +T P  +V+GYG +  + YR  R + VLK EY
Sbjct: 136 VITIPHAFVIGYGMDYAESYRELRDICVLKKEY 168
>ref|YP_001031384.1| hypoxanthine phosphoribosyltransferase [Lactococcus lactis subsp.
           cremoris MG1363]
 emb|CAL96628.1| hpt [Lactococcus lactis subsp. cremoris MG1363]
          Length = 183

 Score =  123 bits (308), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 67/153 (43%), Positives = 107/153 (69%), Gaps = 8/153 (5%)

Query: 77  ENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFT 136
           +NPL++  +L+GS  F A++++++ DC L    DF+ ++SY G TKSSG V+++ ++  T
Sbjct: 38  KNPLVL-GILRGSVPFLAELIKHI-DCHLET--DFMTVSSYHGGTKSSGEVKLILDVD-T 92

Query: 137 ELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLT 196
            + G+ +LI+EDI DTGRT+K L E +  E+R A++K+  L+DKP GR+V+ KP++   T
Sbjct: 93  AVKGREILIVEDIIDTGRTLKYLKELL--EHRGANVKIVTLLDKPEGRIVEIKPDYSGFT 150

Query: 197 APTRYVVGYGFEVNDRYRNYRHVFVLKPE-YAK 228
            P  +VVG+G +  + YRN  +V VLKPE Y+K
Sbjct: 151 IPNEFVVGFGLDYEENYRNLPYVGVLKPEVYSK 183
>ref|YP_808076.1| Hypoxanthine-guanine phosphoribosyltransferase [Lactococcus lactis
           subsp. cremoris SK11]
 gb|ABJ71654.1| hypoxanthine phosphoribosyltransferase [Lactococcus lactis subsp.
           cremoris SK11]
          Length = 183

 Score =  122 bits (307), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 67/153 (43%), Positives = 107/153 (69%), Gaps = 8/153 (5%)

Query: 77  ENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFT 136
           +NPL++  +L+GS  F A++++++ DC L    DF+ ++SY G TKSSG V+++ ++  T
Sbjct: 38  KNPLVL-GILRGSVPFLAELIKHI-DCHLET--DFMTVSSYHGGTKSSGEVKLILDVD-T 92

Query: 137 ELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLT 196
            + G+ +LI+EDI DTGRT+K L E +  E+R A++K+  L+DKP GR+V+ KP++   T
Sbjct: 93  AVKGREILIVEDIIDTGRTLKYLKELL--EHRGANVKIVTLLDKPEGRIVEIKPDYSGFT 150

Query: 197 APTRYVVGYGFEVNDRYRNYRHVFVLKPE-YAK 228
            P  +VVG+G +  + YRN  +V VLKPE Y+K
Sbjct: 151 IPNEFVVGFGLDYEENYRNLPYVGVLKPEVYSK 183
>ref|ZP_01273646.1| Hypoxanthine phosphoribosyl transferase [Lactobacillus reuteri
           100-23]
 gb|EAS89395.1| Hypoxanthine phosphoribosyl transferase [Lactobacillus reuteri
           100-23]
          Length = 180

 Score =  122 bits (307), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 75/194 (38%), Positives = 113/194 (58%), Gaps = 25/194 (12%)

Query: 31  ESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSY 90
           E V+ +E  + + M E+A  L   YK                   D+ P IIISVL G+ 
Sbjct: 6   ERVLYSEEMLGKRMDELATDLTKDYK-------------------DKRP-IIISVLSGAV 45

Query: 91  IFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIA 150
           +FT DM+  L    +   +DFI ++SY G   S+G V+++ +L+ T++  +HVLIMEDI 
Sbjct: 46  LFTVDMIERLD---IMAQIDFIDVSSYFGGLGSTGKVKLIHDLK-TDVKDRHVLIMEDIV 101

Query: 151 DTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVN 210
           DTGRT+K L++ +  +    S+KVC L++KP GR VD +P++V  T P  ++VGYG +  
Sbjct: 102 DTGRTLKYLMD-LLADRGAKSIKVCSLLNKPEGRKVDVEPDYVGFTVPKEFLVGYGLDYK 160

Query: 211 DRYRNYRHVFVLKP 224
             YRN  +V +LKP
Sbjct: 161 GFYRNLPYVGILKP 174
>ref|ZP_03939360.1| hypoxanthine phosphoribosyltransferase [Lactobacillus brevis subsp.
           gravesensis ATCC 27305]
 gb|EEI71308.1| hypoxanthine phosphoribosyltransferase [Lactobacillus brevis subsp.
           gravesensis ATCC 27305]
          Length = 180

 Score =  122 bits (307), Expect = 2e-26,   Method: Composition-based stats.
 Identities = 65/146 (44%), Positives = 101/146 (69%), Gaps = 7/146 (4%)

Query: 81  IIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTG 140
           ++I VLKG+  F +D+VR   D  +   +DFI ++SY GTT+SSG V ++ ++  T+++G
Sbjct: 36  VVIGVLKGATFFMSDIVRQ-ADTYME--IDFIDVSSYHGTTQSSGKVDLVTDIS-TDVSG 91

Query: 141 KHVLIMEDIADTGRTMKLLVEKI-RREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPT 199
           + VLI+EDI DTGRT+K L++ + +R  R  S+KVC L+DKP GR V+   +F+    P 
Sbjct: 92  RDVLIIEDIVDTGRTLKFLMDNLTKRGAR--SIKVCTLLDKPAGRQVEANSDFIGFEVPN 149

Query: 200 RYVVGYGFEVNDRYRNYRHVFVLKPE 225
            +VVGYG + +++YRN  ++ VLKPE
Sbjct: 150 EFVVGYGLDYDEKYRNLPYIGVLKPE 175
>ref|ZP_03958961.1| hypoxanthine phosphoribosyltransferase [Lactobacillus vaginalis
           ATCC 49540]
 gb|EEJ41477.1| hypoxanthine phosphoribosyltransferase [Lactobacillus vaginalis
           ATCC 49540]
          Length = 180

 Score =  122 bits (305), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 71/194 (36%), Positives = 114/194 (58%), Gaps = 25/194 (12%)

Query: 31  ESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSY 90
           E V+ ++  I+R M E+A  L   YK                   D+ PLI+ SV+ G+ 
Sbjct: 6   ERVLYSKDDINRRMDELANQLTAEYK-------------------DQRPLIV-SVMTGAV 45

Query: 91  IFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIA 150
           +FT DM++ +    +   +DFI ++SY G T S+G V+++ +L+ +++ G+ +LIMEDI 
Sbjct: 46  LFTVDMIKRMD---IMAKLDFIDVSSYYGGTSSTGKVKLVQDLK-SDVRGRSILIMEDIV 101

Query: 151 DTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVN 210
           DTG T+K L++ + +E    S+KVC L+DKP GR V+ K ++V    P  ++VGYG +  
Sbjct: 102 DTGHTLKYLID-LLKERGAKSVKVCTLLDKPEGRQVEVKADYVGFNVPNEFLVGYGLDYQ 160

Query: 211 DRYRNYRHVFVLKP 224
             YRN  +V +LKP
Sbjct: 161 GYYRNLPYVGILKP 174
>ref|NP_266176.1| hypoxantine-guanine phosphorybosyltransferase [Lactococcus lactis
           subsp. lactis Il1403]
 sp|Q02522|HPRT_LACLA Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase)
 gb|AAK04118.1|AE006241_7 hypoxantine-guanine phosphorybosyltransferase (EC 2.4.2.8)
           [Lactococcus lactis subsp. lactis Il1403]
 emb|CAA48876.1| hypoxanthine guanine phosphoribosyltransferase [Lactococcus lactis]
 emb|CAA47404.1| hypoxanthine phosphoribosyltransferase [Lactococcus lactis]
 prf||1905381A hypoxanthine guanine phosphoribosyltransferase
          Length = 183

 Score =  122 bits (305), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 65/149 (43%), Positives = 104/149 (69%), Gaps = 7/149 (4%)

Query: 77  ENPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFT 136
           +NPL++  +L+GS  F A++++++ DC L    DF+ ++SY G TKSSG V+++ ++  T
Sbjct: 38  KNPLVL-GILRGSVPFLAELIKHI-DCHLET--DFMTVSSYHGGTKSSGEVKLILDVD-T 92

Query: 137 ELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLT 196
            + G+ +LI+EDI DTGRT+K L E +  E+R A++K+  L+DKP GR+V+ KP++   T
Sbjct: 93  AVKGRDILIVEDIIDTGRTLKYLKELL--EHRGANVKIVTLLDKPEGRIVEIKPDYSGFT 150

Query: 197 APTRYVVGYGFEVNDRYRNYRHVFVLKPE 225
            P  +VVG+G +  + YRN  +V VLKPE
Sbjct: 151 IPNEFVVGFGLDYEENYRNLPYVGVLKPE 179
>ref|ZP_03952458.1| hypoxanthine phosphoribosyltransferase [Lactobacillus hilgardii
           ATCC 8290]
 gb|EEI25779.1| hypoxanthine phosphoribosyltransferase [Lactobacillus hilgardii
           ATCC 8290]
          Length = 180

 Score =  121 bits (304), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 64/146 (43%), Positives = 101/146 (69%), Gaps = 7/146 (4%)

Query: 81  IIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTG 140
           ++I VLKG+  F +D+VR   D  +   +DFI ++SY GTT+SSG V ++ ++  T+++G
Sbjct: 36  VVIGVLKGATFFMSDIVRQ-ADTYME--IDFIDVSSYHGTTQSSGKVDLVTDIS-TDVSG 91

Query: 141 KHVLIMEDIADTGRTMKLLVEKI-RREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPT 199
           + VLI+EDI DTGRT+K L++ + +R  R  S+KVC L+DKP GR ++   +F+    P 
Sbjct: 92  RDVLIIEDIVDTGRTLKFLMDNLTKRGAR--SIKVCTLLDKPAGRQLEANSDFIGFEVPN 149

Query: 200 RYVVGYGFEVNDRYRNYRHVFVLKPE 225
            +VVGYG + +++YRN  ++ VLKPE
Sbjct: 150 EFVVGYGLDYDEKYRNLPYIGVLKPE 175
>ref|ZP_03942372.1| hypoxanthine phosphoribosyltransferase [Lactobacillus buchneri ATCC
           11577]
 gb|EEI19810.1| hypoxanthine phosphoribosyltransferase [Lactobacillus buchneri ATCC
           11577]
          Length = 180

 Score =  121 bits (304), Expect = 3e-26,   Method: Composition-based stats.
 Identities = 65/146 (44%), Positives = 100/146 (68%), Gaps = 7/146 (4%)

Query: 81  IIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTG 140
           ++I VLKG+  F +D+VR   D  +   +DFI ++SY GTT+SSG V ++ ++  T++ G
Sbjct: 36  VVIGVLKGATFFMSDIVRQ-ADTYME--IDFIDVSSYHGTTQSSGKVDLVTDIS-TDVFG 91

Query: 141 KHVLIMEDIADTGRTMKLLVEKI-RREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPT 199
           + VLI+EDI DTGRT+K L++ + +R  R  S+KVC L+DKP GR V+   +F+    P 
Sbjct: 92  RDVLIIEDIVDTGRTLKFLMDNLTKRGAR--SIKVCTLLDKPAGRQVEANSDFIGFEVPN 149

Query: 200 RYVVGYGFEVNDRYRNYRHVFVLKPE 225
            +VVGYG + +++YRN  ++ VLKPE
Sbjct: 150 EFVVGYGLDYDEKYRNLPYIGVLKPE 175
>ref|YP_001270874.1| hypoxanthine phosphoribosyltransferase [Lactobacillus reuteri F275]
 ref|YP_001841252.1| hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus
           reuteri F275]
 gb|ABQ82537.1| hypoxanthine phosphoribosyltransferase [Lactobacillus reuteri F275]
 dbj|BAG24772.1| hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus
           reuteri F275]
          Length = 180

 Score =  121 bits (304), Expect = 4e-26,   Method: Composition-based stats.
 Identities = 74/194 (38%), Positives = 112/194 (57%), Gaps = 25/194 (12%)

Query: 31  ESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSY 90
           E V+ +E  + + M E+A  L   YK                   D+ P IIISVL G+ 
Sbjct: 6   ERVLYSEEMLGKRMDELATDLTKDYK-------------------DKRP-IIISVLSGAV 45

Query: 91  IFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIA 150
           +FT DM+  L    +   +DFI ++SY G   S+G V+++ +L+  ++  +HVLIMEDI 
Sbjct: 46  LFTVDMIERLD---IMAQIDFIDVSSYFGGLGSTGKVKLIHDLKI-DVKDRHVLIMEDIV 101

Query: 151 DTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVN 210
           DTGRT+K L++ +  +    S+KVC L++KP GR VD +P++V  T P  ++VGYG +  
Sbjct: 102 DTGRTLKYLMD-LLADRGAKSIKVCSLLNKPEGRKVDIEPDYVGFTVPKEFLVGYGLDYK 160

Query: 211 DRYRNYRHVFVLKP 224
             YRN  +V +LKP
Sbjct: 161 GFYRNLPYVGILKP 174
>ref|YP_001513548.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus oremlandii
           OhILAs]
 gb|ABW19552.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus oremlandii
           OhILAs]
          Length = 179

 Score =  120 bits (302), Expect = 6e-26,   Method: Composition-based stats.
 Identities = 66/152 (43%), Positives = 102/152 (67%), Gaps = 8/152 (5%)

Query: 74  ITDE---NPLIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVL 130
           I+DE     L +IS+L+GS++FTAD+VR L    +P  +DF+  +SY   T+SSGTVQ++
Sbjct: 28  ISDEYRDKKLYVISLLRGSFVFTADLVRKLD---IPVKIDFMTTSSYGHDTESSGTVQIV 84

Query: 131 DNLRFTELTGKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKP 190
            +++   L   HVL+++DI D+G TMK +++ ++ +  P S+K CVL+DKP  R V+  P
Sbjct: 85  TDIK-ENLEDYHVLVVDDITDSGLTMKFVMDHLKTK-NPQSVKSCVLLDKPERRKVEIVP 142

Query: 191 EFVCLTAPTRYVVGYGFEVNDRYRNYRHVFVL 222
           ++V  T P ++VVGYG    D YRN  +VFV+
Sbjct: 143 DYVGFTIPDKFVVGYGLNYGDYYRNIPYVFVV 174
>ref|ZP_03974729.1| hypoxanthine phosphoribosyltransferase [Lactobacillus reuteri
           CF48-3A]
 ref|ZP_04023698.1| hypoxanthine phosphoribosyltransferase [Lactobacillus reuteri
           SD2112]
 gb|EEI65397.1| hypoxanthine phosphoribosyltransferase [Lactobacillus reuteri
           CF48-3A]
 gb|EEJ92158.1| hypoxanthine phosphoribosyltransferase [Lactobacillus reuteri
           SD2112]
          Length = 180

 Score =  120 bits (302), Expect = 7e-26,   Method: Composition-based stats.
 Identities = 74/194 (38%), Positives = 112/194 (57%), Gaps = 25/194 (12%)

Query: 31  ESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSY 90
           E V+ +E  + + M E+A  L   YK                   D+ P IIISVL G+ 
Sbjct: 6   ERVLYSEEMLGKRMDELATDLTKDYK-------------------DKRP-IIISVLSGAV 45

Query: 91  IFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIA 150
           +FT DM+  L    +   +DFI ++SY G   S+G V+++ +L+ T++  +HVLIMEDI 
Sbjct: 46  LFTVDMIERLD---IMAQIDFIDVSSYFGGLGSTGKVKLIHDLK-TDVKDRHVLIMEDIV 101

Query: 151 DTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVN 210
           DTG T+K L++ +  +    S+KVC L++KP GR VD +P++V  T P  ++VGYG +  
Sbjct: 102 DTGHTLKYLMD-LLADRGAKSIKVCSLLNKPEGREVDVEPDYVGFTVPKEFLVGYGLDYK 160

Query: 211 DRYRNYRHVFVLKP 224
             YRN  +V +LKP
Sbjct: 161 GFYRNLPYVGILKP 174
>ref|YP_074329.1| hypoxanthine-guanine phosphoribosyltransferase [Symbiobacterium
           thermophilum IAM 14863]
 dbj|BAD39485.1| hypoxanthine-guanine phosphoribosyltransferase [Symbiobacterium
           thermophilum IAM 14863]
          Length = 179

 Score =  120 bits (301), Expect = 8e-26,   Method: Composition-based stats.
 Identities = 72/198 (36%), Positives = 109/198 (55%), Gaps = 25/198 (12%)

Query: 31  ESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSY 90
           E V+ TE  I   +KE+   ++  ++                       L+++ +LKG+ 
Sbjct: 6   ERVLITEEQIREKIKELGAQISEDFRG--------------------KDLVVVGILKGAA 45

Query: 91  IFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIA 150
           +F AD+ R +    +P  +DF+RITSY   TKS+G  +VL +L +T L G+HVLI+EDI 
Sbjct: 46  LFCADLFRAIS---IPAELDFMRITSYGAATKSTGVHRVLLDLDYT-LEGRHVLIVEDIV 101

Query: 151 DTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVN 210
           DTG T+K L E + +   PASL V  L+DKP  R V+   ++     P  +VVG G +  
Sbjct: 102 DTGLTIKFLKEYLSQR-GPASLSVAALLDKPSRRKVEVTIDYRGFEVPDFFVVGMGLDYA 160

Query: 211 DRYRNYRHVFVLKPEYAK 228
           ++YRN R + +LKPE  K
Sbjct: 161 EKYRNLRDICILKPEIYK 178
>ref|ZP_03856512.1| hypoxanthine phosphoribosyltransferase [Thermobaculum terrenum ATCC
           BAA-798]
 gb|EEI02034.1| hypoxanthine phosphoribosyltransferase [Thermobaculum terrenum ATCC
           BAA-798]
          Length = 186

 Score =  120 bits (301), Expect = 9e-26,   Method: Composition-based stats.
 Identities = 67/194 (34%), Positives = 114/194 (58%), Gaps = 25/194 (12%)

Query: 31  ESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSY 90
           E ++ TES +   +KE+   +A  YK                   D+ P ++I VL G+ 
Sbjct: 6   EQILITESELQAKIKELGSRIAEDYK-------------------DKIP-VLIGVLNGAV 45

Query: 91  IFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIA 150
           +F +D++R    C +   +DF+ ++SY+ +T+SSG V+++ +L    ++G+H+LI+EDI 
Sbjct: 46  MFVSDLIRA---CPIQLNIDFMAVSSYQDSTESSGVVKIIKDLD-RNISGRHILIVEDII 101

Query: 151 DTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVN 210
           DTG T+  L+E ++  + PAS+KVC L+DK   R V+   +++    P ++VVGYG +  
Sbjct: 102 DTGLTLSYLLETLQARH-PASIKVCALLDKASRRRVNVPIDYLGFQIPDKFVVGYGLDFR 160

Query: 211 DRYRNYRHVFVLKP 224
           D YRN  ++ VLKP
Sbjct: 161 DLYRNLPYIGVLKP 174
>ref|ZP_00874757.1| Hypoxanthine phosphoribosyl transferase [Streptococcus suis
           89/1591]
 gb|EAP41089.1| Hypoxanthine phosphoribosyl transferase [Streptococcus suis
           89/1591]
          Length = 180

 Score =  119 bits (298), Expect = 2e-25,   Method: Composition-based stats.
 Identities = 68/195 (34%), Positives = 113/195 (57%), Gaps = 25/195 (12%)

Query: 31  ESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSY 90
           + ++ +E  I    KE+ Q LA  Y                    D+NP I++ +LKGS 
Sbjct: 7   KKILVSEEEIVAKCKELGQILATDY-------------------ADKNP-ILVGILKGSI 46

Query: 91  IFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIA 150
            F A++++++ D  +    D++ ++SY G T+S GTV+++ +L    + G+H++ +EDI 
Sbjct: 47  PFMAELMKHI-DAHVET--DYMVVSSYHGGTESCGTVKIIKDLD-NSVAGRHIIFIEDII 102

Query: 151 DTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVN 210
           DTGRT+K L E      +  S+K+  L+DKP GRVV+ +P++ C T P  +VVG+G + +
Sbjct: 103 DTGRTLKELKELFALR-QAGSIKIATLLDKPEGRVVEIEPDYTCFTIPNEFVVGFGLDYD 161

Query: 211 DRYRNYRHVFVLKPE 225
           + YRN  +V VLK E
Sbjct: 162 ENYRNLPYVGVLKEE 176
>ref|ZP_01666882.1| hypoxanthine phosphoribosyltransferase [Thermosinus carboxydivorans
           Nor1]
 gb|EAX47240.1| hypoxanthine phosphoribosyltransferase [Thermosinus carboxydivorans
           Nor1]
          Length = 179

 Score =  118 bits (296), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 60/149 (40%), Positives = 99/149 (66%), Gaps = 5/149 (3%)

Query: 80  LIIISVLKGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELT 139
           +++I VL+G+ IF AD+ R +    +P  +DF+ ++SY  +T SSG V++L +L   ++ 
Sbjct: 35  ILMIGVLRGAVIFMADLARAID---VPVALDFMAVSSYGASTTSSGVVRILKDLD-EDVE 90

Query: 140 GKHVLIMEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPT 199
           GKH+LI+EDI D+G T+  L++ +R   +PAS+K+C L++KP  R VD + ++   T P 
Sbjct: 91  GKHLLIVEDIIDSGLTLNYLLDNLRSR-KPASIKICTLLNKPERRKVDVQVDYNGFTIPD 149

Query: 200 RYVVGYGFEVNDRYRNYRHVFVLKPEYAK 228
            +VVGYG +  ++YRN   + +LKPE  K
Sbjct: 150 HFVVGYGLDYAEKYRNLPFIGILKPEAYK 178
>emb|CAJ74742.1| similar to hypoxanthine-guanine-xanthine phosphoribosyltransferase
           [Candidatus Kuenenia stuttgartiensis]
          Length = 189

 Score =  118 bits (296), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 70/197 (35%), Positives = 109/197 (55%), Gaps = 25/197 (12%)

Query: 33  VVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVLKGSYIF 92
           VV +E  I   + E++ TL N Y+        NK               II++L GS +F
Sbjct: 14  VVISEKQIKEKLVELSNTLINTYQ--------NK------------EWTIIAILNGSLVF 53

Query: 93  TADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQVLDNLRFTELTGKHVLIMEDIADT 152
            AD++R++        +D I  +SY  +T S G V ++ N +  ++ GKHVL+++DI DT
Sbjct: 54  LADLIRHIP---FSIRLDTIDASSYGDSTISKGEVNIIHNFKI-DIEGKHVLVIDDIVDT 109

Query: 153 GRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGYGFEVNDR 212
           G T+K ++  I++ Y PASLK CVL+ + G R    KP++ C      +VVGYG + N++
Sbjct: 110 GNTLKKVLADIKK-YAPASLKSCVLLSRSGRRQNKIKPDYCCFNVGDDFVVGYGLDYNNK 168

Query: 213 YRNYRHVFVLKPEYAKR 229
           YRN  ++ VLK E  +R
Sbjct: 169 YRNLPYIAVLKDECYRR 185
Searching..................................................done Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|XP_822397.1|  hypoxanthine-guanine phosphoribosyltransfe...   347   4e-94
ref|YP_001113711.1|  hypoxanthine phosphoribosyltransferase ...   281   2e-74
ref|ZP_01666882.1|  hypoxanthine phosphoribosyltransferase [...   279   8e-74
ref|YP_002769603.1|  hypoxanthine-guanine phosphoribosyltran...   276   8e-73
ref|ZP_01514399.1|  hypoxanthine phosphoribosyltransferase [...   276   1e-72
ref|XP_816917.1|  hypoxanthine-guanine phosphoribosyltransfe...   274   3e-72
ref|XP_813397.1|  hypoxanthine-guanine phosphoribosyltransfe...   274   3e-72
ref|XP_001564805.1|  xanthine phosphoribosyltransferase [Lei...   274   4e-72
gb|EEJ98066.1|  hypoxanthine phosphoribosyltransferase [Ther...   273   6e-72
ref|YP_359913.1|  hypoxanthine phosphoribosyltransferase [Ca...   273   6e-72
pdb|1PZM|A  Chain A, Crystal Structure Of Hgprt-Ase From Lei...   272   1e-71
ref|NP_469596.1|  fusion protein, N-terminal part similar to...   272   1e-71
ref|NP_463750.1|  fusion protein, N-terminal part similar to...   271   2e-71
ref|ZP_02686823.1|  hypothetical protein LmonFSL_00295 [List...   271   2e-71
ref|YP_012840.1|  conserved hypothetical protein/hypoxanthin...   271   2e-71
ref|ZP_01926199.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   271   2e-71
ref|ZP_02276207.1|  hypothetical protein LmonFS_00952 [Liste...   271   2e-71
ref|ZP_01928838.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   271   3e-71
ref|ZP_00230936.1|  conserved hypothetical protein/hypoxanth...   271   3e-71
ref|ZP_01942347.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   271   3e-71
ref|ZP_02330217.1|  hypothetical protein Plarl_21636 [Paenib...   270   6e-71
ref|YP_001213102.1|  hypoxanthine-guanine phosphoribosyltran...   270   6e-71
ref|YP_001512894.1|  hypoxanthine phosphoribosyltransferase ...   270   6e-71
ref|YP_644942.1|  hypoxanthine phosphoribosyltransferase [Ru...   270   7e-71
ref|XP_001683026.1|  xanthine phosphoribosyltransferase [Lei...   269   8e-71
gb|AAD50967.1|AF170105_2  xanthine phosphoribosyltransferase...   269   1e-70
ref|YP_001256007.1|  hypoxanthine phosphoribosyltransferase ...   269   1e-70
ref|ZP_02618270.1|  hypoxanthine phosphoribosyltransferase [...   269   1e-70
ref|ZP_02993965.1|  hypothetical protein CLOSPO_01067 [Clost...   269   2e-70
ref|YP_848383.1|  conserved hypothetical/hypoxanthine phosph...   268   2e-70
ref|NP_627611.1|  hypoxanthine phosphoribosyltransferase [St...   267   4e-70
ref|YP_001274703.1|  hypoxanthine phosphoribosyltransferase ...   267   5e-70
ref|NP_825842.1|  hypoxanthine phosphoribosyltransferase [St...   267   5e-70
ref|XP_001463947.1|  HGPRT,hypoxanthine-guanine phosphoribos...   267   5e-70
ref|ZP_02091227.1|  hypothetical protein FAEPRAM212_01498 [F...   266   9e-70
ref|XP_001683025.1|  hypoxanthine-guanine phosphoribosyltran...   265   1e-69
ref|ZP_02849796.1|  hypoxanthine phosphoribosyltransferase [...   265   2e-69
ref|NP_814058.1|  hypoxanthine-guanine phosphoribosyltransfe...   265   2e-69
ref|YP_001695855.1|  Hypoxanthine-guanine phosphoribosyltran...   264   3e-69
ref|ZP_02037643.1|  hypothetical protein BACCAP_03261 [Bacte...   264   3e-69
ref|ZP_02581448.1|  hypoxanthine phosphoribosyltransferase [...   264   3e-69
ref|ZP_00741717.1|  Hypoxanthine-guanine phosphoribosyltrans...   264   3e-69
ref|ZP_03924809.1|  hypoxanthine phosphoribosyltransferase [...   264   4e-69
ref|YP_001485312.1|  hypoxanthine phosphoribosyltransferase ...   264   4e-69
ref|YP_001320712.1|  hypoxanthine phosphoribosyltransferase ...   264   4e-69
ref|ZP_03922784.1|  hypoxanthine phosphoribosyltransferase [...   264   4e-69
ref|YP_001825599.1|  putative hypoxanthine phosphoribosyltra...   264   5e-69
ref|YP_001642956.1|  hypoxanthine phosphoribosyltransferase ...   264   5e-69
ref|YP_001430999.1|  hypoxanthine phosphoribosyltransferase ...   263   6e-69
ref|YP_001373429.1|  hypoxanthine phosphoribosyltransferase ...   263   7e-69
ref|ZP_04009409.1|  hypoxanthine-guanine phosphoribosyltrans...   263   9e-69
ref|ZP_01725398.1|  hypoxanthine-guanine phosphoribosyltrans...   263   9e-69
ref|ZP_02525183.1|  hypoxanthine phosphoribosyltransferase [...   263   1e-68
ref|ZP_00603444.1|  Hypoxanthine phosphoribosyl transferase ...   263   1e-68
ref|NP_842632.1|  hypoxanthine-guanine phosphoribosyltransfe...   262   1e-68
ref|ZP_03982713.1|  Hypoxanthine phosphoribosyltransferase [...   262   1e-68
sp|Q27541|HPRT_CRIFA  Hypoxanthine-guanine phosphoribosyltra...   262   1e-68
ref|YP_536242.1|  Hypoxanthine-guanine phosphoribosyltransfe...   262   1e-68
ref|YP_001539489.1|  hypoxanthine phosphoribosyltransferase ...   262   1e-68
ref|ZP_01950602.1|  hypoxanthine phosphoribosyltransferase [...   262   2e-68
ref|ZP_01236067.1|  hypoxanthine-guanine phosphoribosyltrans...   261   2e-68
ref|ZP_02263469.1|  hypoxanthine phosphoribosyltransferase [...   261   2e-68
ref|ZP_02281563.1|  hypothetical protein LmonL_01842 [Lister...   261   4e-68
ref|ZP_03856335.1|  hypoxanthine phosphoribosyltransferase [...   261   4e-68
ref|ZP_01189486.1|  Hypoxanthine phosphoribosyl transferase ...   261   4e-68
ref|YP_173609.1|  hypoxanthine-guanine phosphoribosyltransfe...   261   4e-68
ref|YP_520172.1|  hypothetical protein DSY3939 [Desulfitobac...   261   4e-68
ref|NP_240950.1|  hypoxanthine-guanine phosphoribosyltransfe...   261   4e-68
dbj|BAF43658.1|  hypoxanthine ribosyl transferase [Photobact...   260   6e-68
ref|NP_829966.1|  hypoxanthine-guanine phosphoribosyltransfe...   260   6e-68
ref|ZP_02185480.1|  hypoxanthine-guanine phosphoribosyltrans...   260   6e-68
ref|ZP_01160633.1|  hypoxanthine-guanine phosphoribosyltrans...   260   6e-68
ref|YP_001678694.1|  hypoxanthine phosphoribosyltransferase ...   260   6e-68
ref|YP_001161115.1|  hypoxanthine phosphoribosyltransferase ...   260   7e-68
ref|NP_230235.1|  hypoxanthine-guanine phosphoribosyltransfe...   260   7e-68
ref|ZP_03856512.1|  hypoxanthine phosphoribosyltransferase [...   259   9e-68
ref|YP_290952.1|  hypoxanthine phosphoribosyl transferase [T...   259   9e-68
ref|YP_877129.1|  hypoxanthine phosphoribosyltransferase [Cl...   259   9e-68
ref|YP_001557268.1|  hypoxanthine phosphoribosyltransferase ...   259   1e-67
dbj|BAF43662.1|  hypoxanthine ribosyl transferase [Vibrio fi...   259   1e-67
ref|YP_205559.1|  hypoxanthine phosphoribosyltransferase [Vi...   259   1e-67
ref|YP_074329.1|  hypoxanthine-guanine phosphoribosyltransfe...   259   1e-67
ref|ZP_03927309.1|  hypoxanthine phosphoribosyltransferase [...   259   2e-67
ref|ZP_02278787.1|  hypothetical protein LmonF_02357 [Lister...   258   2e-67
ref|ZP_02951334.1|  hypoxanthine phosphoribosyltransferase [...   258   3e-67
ref|ZP_01481302.1|  hypothetical protein VchoR_02002821 [Vib...   258   3e-67
ref|ZP_03826612.1|  hypoxanthine-guanine phosphoribosyltrans...   258   3e-67
ref|ZP_03833725.1|  hypoxanthine-guanine phosphoribosyltrans...   258   3e-67
ref|ZP_01992529.1|  hypoxanthine phosphoribosyltransferase [...   257   3e-67
ref|ZP_02643856.1|  hypoxanthine phosphoribosyltransferase [...   257   3e-67
ref|NP_780915.1|  hypoxanthine-guanine phosphoribosyltransfe...   257   3e-67
ref|NP_798894.1|  hypoxanthine-guanine phosphoribosyltransfe...   257   4e-67
ref|YP_697159.1|  hypoxanthine phosphoribosyltransferase [Cl...   257   4e-67
gb|AAB41678.1|  hypoxanthine-guanine phosphoribosyltransferase    257   4e-67
ref|NP_563387.1|  hypoxanthine-guanine phosphoribosyltransfe...   257   4e-67
emb|CAG76226.1|  hypoxanthine phosphoribosyltransferase [Erw...   257   4e-67
emb|CAG21486.1|  putative hypoxanthine ribosyl transferase [...   257   5e-67
ref|XP_001564804.1|  hypoxanthine-guanine phosphoribosyltran...   257   5e-67
ref|YP_051417.2|  hypoxanthine-guanine phosphoribosyltransfe...   257   5e-67
ref|YP_001916267.1|  hypoxanthine phosphoribosyltransferase ...   257   5e-67
ref|YP_001626350.1|  hypoxanthine-guanine phosphoribosyltran...   257   5e-67
ref|ZP_00832718.1|  COG0634: Hypoxanthine-guanine phosphorib...   257   6e-67
ref|NP_935562.1|  hypoxanthine-guanine phosphoribosyltransfe...   257   6e-67
ref|ZP_01262549.1|  hypoxanthine-guanine phosphoribosyltrans...   257   6e-67
ref|ZP_00994139.1|  putative hypoxanthine phosphoribosyltran...   256   7e-67
ref|ZP_00379834.1|  COG0634: Hypoxanthine-guanine phosphorib...   256   7e-67
ref|ZP_01988476.1|  hypoxanthine phosphoribosyltransferase [...   256   8e-67
ref|YP_131288.2|  hypoxanthine-guanine phosphoribosyltransfe...   256   8e-67
ref|XP_816916.1|  hypoxanthine-guanine phosphoribosyltransfe...   256   8e-67
ref|YP_001906795.1|  Hypoxanthine phosphoribosyltransferase ...   256   8e-67
ref|ZP_01220020.1|  hypoxanthine-guanine phosphoribosyltrans...   256   8e-67
ref|NP_406870.1|  hypoxanthine-guanine phosphoribosyltransfe...   256   9e-67
ref|YP_652817.1|  hypoxanthine phosphoribosyltransferase [Ye...   256   9e-67
ref|NP_668114.2|  hypoxanthine-guanine phosphoribosyltransfe...   256   1e-66
ref|YP_001635640.1|  hypoxanthine phosphoribosyltransferase ...   256   1e-66
sp|P18134|HPRT_VIBHA  Hypoxanthine phosphoribosyltransferase...   256   1e-66
ref|YP_138556.1|  hypoxanthine-guanine phosphoribosyltransfe...   256   1e-66
ref|ZP_02444150.1|  hypothetical protein ANACOL_03471 [Anaer...   256   1e-66
ref|ZP_01815583.1|  hypoxanthine-guanine phosphoribosyltrans...   256   1e-66
ref|YP_699727.1|  hypoxanthine phosphoribosyltransferase [Cl...   255   2e-66
ref|ZP_03958058.1|  hypoxanthine-guanine phosphoribosyltrans...   255   2e-66
ref|ZP_03994351.1|  hypoxanthine phosphoribosyltransferase [...   255   2e-66
pdb|1TC2|A  Chain A, Ternary Substrate Complex Of The Hypoxa...   255   2e-66
ref|ZP_02081126.1|  hypothetical protein CLOLEP_02599 [Clost...   255   2e-66
ref|ZP_00826602.1|  COG0634: Hypoxanthine-guanine phosphorib...   255   2e-66
pdb|1TC1|A  Chain A, A 1.4 Angstrom Crystal Structure For Th...   255   2e-66
ref|NP_690999.1|  hypoxanthine phosphoribosyltransferase [Oc...   254   3e-66
ref|YP_807706.1|  Hypoxanthine-guanine phosphoribosyltransfe...   254   3e-66
ref|ZP_03868259.1|  hypoxanthine phosphoribosyltransferase [...   254   3e-66
ref|YP_069264.1|  hypoxanthine-guanine phosphoribosyltransfe...   254   3e-66
ref|YP_001402308.1|  hypoxanthine phosphoribosyltransferase ...   254   4e-66
pdb|1P17|A  Chain A, Hypoxanthine Phosphoribosyltransferase ...   254   4e-66
ref|ZP_01896236.1|  hypoxanthine-guanine phosphoribosyltrans...   254   4e-66
ref|YP_001333823.1|  hypoxanthine-guanine phosphoribosyltran...   254   4e-66
ref|XP_001691549.1|  hypothetical protein CHLREDRAFT_145152 ...   254   4e-66
ref|YP_001480221.1|  hypoxanthine phosphoribosyltransferase ...   254   5e-66
ref|YP_001360283.1|  hypoxanthine phosphoribosyltransferase ...   254   5e-66
ref|XP_813396.1|  hypoxanthine-guanine phosphoribosyltransfe...   253   6e-66
ref|YP_254416.1|  putative hypoxanthine-guanine phosphoribos...   253   7e-66
ref|YP_001574409.1|  hypoxanthine phosphoribosyltransferase ...   253   8e-66
ref|YP_001439265.1|  hypothetical protein ESA_03207 [Enterob...   253   8e-66
ref|YP_493197.1|  hypoxanthine phosphoribosyltransferase [St...   253   9e-66
ref|NP_687051.1|  hypoxanthine-guanine phosphoribosyltransfe...   253   9e-66
ref|ZP_01995978.1|  hypothetical protein DORLON_01976 [Dorea...   252   9e-66
ref|ZP_02042278.1|  hypothetical protein RUMGNA_03077 [Rumin...   252   9e-66
pdb|1I14|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   252   1e-65
ref|YP_001586484.1|  hypothetical protein SPAB_00209 [Salmon...   252   1e-65
pdb|1I0L|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   252   1e-65
gb|AAF61462.1|AF139722_1  hypoxanthine-guanine phosphoribosy...   252   1e-65
ref|ZP_02919438.1|  hypothetical protein STRINF_00277 [Strep...   252   1e-65
gb|AAX64076.1|  hypoxanthine phosphoribosyltransferase [Salm...   252   1e-65
ref|YP_001545794.1|  hypoxanthine phosphoribosyltransferase ...   252   1e-65
ref|NP_371034.1|  hypoxanthine-guanine phosphoribosyltransfe...   252   1e-65
ref|NP_720499.1|  hypoxanthine-guanine phosphoribosyltransfe...   252   2e-65
ref|ZP_03910773.1|  hypoxanthine phosphoribosyltransferase [...   252   2e-65
pdb|1I0I|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   252   2e-65
emb|CAE13159.1|  unnamed protein product [Photorhabdus lumin...   252   2e-65
ref|NP_928203.2|  hypoxanthine-guanine phosphoribosyltransfe...   252   2e-65
ref|YP_149518.1|  hypoxanthine-guanine phosphoribosyltransfe...   251   2e-65
ref|ZP_02991800.1|  hypoxanthine phosphoribosyltransferase [...   251   2e-65
ref|NP_459175.1|  hypoxanthine-guanine phosphoribosyltransfe...   251   3e-65
ref|ZP_02685950.1|  hypothetical protein Salmentericaenteric...   251   3e-65
ref|NP_454783.1|  hypoxanthine-guanine phosphoribosyltransfe...   251   3e-65
ref|YP_396211.1|  Hypoxanthine phosphoribosyltranferase [Lac...   251   3e-65
pdb|1I13|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   251   3e-65
ref|ZP_01129459.1|  hypoxanthine phosphoribosyltransferase [...   251   3e-65
ref|YP_687706.1|  hypoxanthine phosphoribosyltransferase [Sh...   251   3e-65
ref|YP_921672.1|  hypoxanthine phosphoribosyltransferase [No...   251   4e-65
ref|ZP_03845145.1|  hypoxanthine-guanine phosphoribosyltrans...   251   4e-65
ref|NP_349799.1|  Hypoxanthine-guanine phosphoribosyltransfe...   251   4e-65
ref|ZP_02348869.1|  hypothetical protein Sententeri_03139 [S...   251   4e-65
ref|YP_001812555.1|  hypoxanthine phosphoribosyltransferase ...   251   4e-65
ref|YP_001884418.1|  hypoxanthine phosphoribosyltransferase ...   250   5e-65
ref|YP_001307245.1|  hypoxanthine phosphoribosyltransferase ...   250   5e-65
ref|ZP_01869538.1|  hypoxanthine-guanine phosphoribosyltrans...   250   5e-65
ref|YP_794711.1|  Hypoxanthine-guanine phosphoribosyltransfe...   250   5e-65
ref|ZP_02653366.1|  hypothetical protein Sententeric_20357 [...   250   5e-65
ref|ZP_03986123.1|  hypoxanthine phosphoribosyltransferase [...   250   6e-65
pdb|1R3U|A  Chain A, Crystal Structure Of Hypoxanthine-Guani...   250   6e-65
ref|YP_001571814.1|  hypothetical protein SARI_02824 [Salmon...   250   6e-65
ref|YP_001175411.1|  hypoxanthine phosphoribosyltransferase ...   250   7e-65
ref|NP_623929.1|  Hypoxanthine-guanine phosphoribosyltransfe...   249   8e-65
ref|YP_001919611.1|  hypoxanthine phosphoribosyltransferase ...   249   8e-65
ref|YP_001664305.1|  hypoxanthine phosphoribosyltransferase ...   249   8e-65
ref|ZP_03813362.1|  hypoxanthine phosphoribosyltransferase [...   249   8e-65
ref|YP_302336.1|  putative hypoxanthine-guanine phosphoribos...   249   9e-65
ref|YP_001843036.1|  hypoxanthine-guanine phosphoribosyltran...   249   9e-65
ref|ZP_02832830.1|  hypothetical protein Salentericaenterica...   249   9e-65
ref|ZP_02340312.1|  hypothetical protein Sentent_15771 [Salm...   249   1e-64
ref|ZP_00134029.2|  COG0634: Hypoxanthine-guanine phosphorib...   249   1e-64
ref|YP_002806730.1|  hypoxanthine-guanine phosphoribosyltran...   249   1e-64
ref|NP_928199.1|  hypoxanthine-guanine phosphoribosyltransfe...   249   1e-64
ref|YP_309162.2|  hypoxanthine phosphoribosyltransferase [Sh...   249   1e-64
ref|NP_765828.1|  hypoxanthine-guanine phosphoribosyltransfe...   249   1e-64
ref|YP_539179.1|  hypoxanthine phosphoribosyltransferase [Es...   249   1e-64
ref|ZP_02210445.1|  hypothetical protein CLOBAR_02853 [Clost...   249   1e-64
ref|ZP_03835281.1|  hypothetical protein CATC2_04748 [Citrob...   249   1e-64
ref|NP_308156.2|  hypoxanthine-guanine phosphoribosyltransfe...   248   2e-64
ref|ZP_00718322.1|  COG0634: Hypoxanthine-guanine phosphorib...   248   2e-64
ref|ZP_02903074.1|  hypoxanthine phosphoribosyltransferase [...   248   2e-64
gb|AAZ86927.1|  hypoxanthine phosphoribosyltransferase [Shig...   248   2e-64
ref|YP_001053387.1|  yypoxanthine phosphoribosyltransferase ...   248   2e-64
ref|YP_001034033.1|  Hypoxanthine guanine phosphoribosyltran...   248   2e-64
ref|YP_001726475.1|  hypoxanthine phosphoribosyltransferase ...   248   3e-64
ref|YP_735273.1|  hypoxanthine phosphoribosyltransferase [Sh...   248   3e-64
ref|YP_001454762.1|  hypothetical protein CKO_03242 [Citroba...   247   3e-64
ref|ZP_02288498.1|  hypothetical protein LmonocyFSL_01672 [L...   247   3e-64
ref|ZP_01704836.1|  hypoxanthine phosphoribosyltransferase [...   247   3e-64
gb|EEH95076.1|  hypoxanthine-guanine phosphoribosyltransfera...   247   3e-64
ref|ZP_04002769.1|  hypoxanthine phosphoribosyltransferase [...   247   3e-64
ref|YP_062949.1|  hypoxanthine phosphoribosyltransferase [Le...   247   4e-64
ref|YP_001742252.1|  hypoxanthine phosphoribosyltransferase ...   247   4e-64
ref|ZP_02478331.1|  hypoxanthine phosphoribosyltransferase [...   247   4e-64
ref|NP_784322.1|  hypoxanthine-guanine phosphoribosyltransfe...   247   5e-64
ref|XP_638364.1|  hypoxanthine phosphoribosyltransferase [Di...   247   6e-64
ref|YP_001221583.1|  hypothetical protein CMM_0843 [Clavibac...   247   6e-64
ref|ZP_01965205.1|  hypothetical protein RUMOBE_02936 [Rumin...   247   6e-64
ref|ZP_02431763.1|  hypothetical protein CLOSCI_01994 [Clost...   247   6e-64
ref|YP_001708886.1|  putative hypoxanthine phosphoribosyltra...   246   7e-64
ref|YP_964712.1|  hypoxanthine phosphoribosyltransferase [Sh...   246   7e-64
ref|YP_001672979.1|  hypoxanthine phosphoribosyltransferase ...   246   7e-64
ref|ZP_03894492.1|  hypoxanthine phosphoribosyltransferase [...   246   7e-64
ref|ZP_01825459.1|  hypoxanthine phosphoribosyltransferase [...   246   9e-64
ref|ZP_01841716.1|  hypoxanthine phosphoribosyltransferase [...   246   9e-64
ref|NP_439311.1|  hypoxanthine-guanine phosphoribosyltransfe...   246   1e-63
ref|NP_344565.1|  hypoxanthine-guanine phosphoribosyltransfe...   246   1e-63
pdb|1G9S|A  Chain A, Crystal Structure Of A Complex Between ...   246   1e-63
ref|ZP_01788849.1|  hypoxanthine-guanine phosphoribosyltrans...   246   1e-63
gb|EEK06649.1|  hypoxanthine phosphoribosyltransferase [Brac...   246   1e-63
ref|ZP_03860374.1|  hypoxanthine phosphoribosyltransferase [...   246   1e-63
ref|YP_001197388.1|  Hypoxanthine-guanine phosphoribosyltran...   246   1e-63
ref|ZP_00874757.1|  Hypoxanthine phosphoribosyl transferase ...   245   2e-63
ref|ZP_00155585.2|  COG0634: Hypoxanthine-guanine phosphorib...   245   2e-63
ref|ZP_01783677.1|  hypoxanthine-guanine phosphoribosyltrans...   245   2e-63
ref|ZP_02961601.2|  hypothetical protein PROSTU_03641 [Provi...   245   2e-63
gb|ABY56069.1|  hypoxanthine phosphoribosyltransferase [uncu...   245   2e-63
ref|NP_719339.1|  hypoxanthine phosphoribosyltransferase [Sh...   245   2e-63
ref|YP_001715593.1|  hypoxanthine phosphoribosyltransferase ...   245   2e-63
ref|YP_001331506.1|  hypoxanthine phosphoribosyltransferase ...   244   3e-63
ref|ZP_02943585.1|  hypoxanthine phosphoribosyltransferase [...   244   3e-63
ref|YP_001451359.1|  hypoxanthine phosphoribosyltransferase ...   244   3e-63
ref|ZP_03884487.1|  hypoxanthine phosphoribosyltransferase [...   244   3e-63
ref|ZP_01967905.1|  hypothetical protein RUMTOR_01471 [Rumin...   244   4e-63
ref|ZP_01772665.1|  Hypothetical protein COLAER_01679 [Colli...   244   4e-63
ref|YP_001095267.1|  hypoxanthine phosphoribosyltransferase ...   244   4e-63
pdb|2GEB|A  Chain A, Crystal Structure Of The Thermoanaeroba...   244   4e-63
ref|YP_001708669.1|  hypoxanthine phosphoribosyltransferase ...   244   4e-63
ref|YP_001049118.1|  hypoxanthine phosphoribosyltransferase ...   244   5e-63
ref|ZP_02169053.1|  Hypoxanthine phosphoribosyltransferase [...   244   5e-63
ref|YP_645559.1|  hypoxanthine phosphoribosyltransferase [Ru...   244   6e-63
ref|ZP_00156993.1|  COG0634: Hypoxanthine-guanine phosphorib...   244   6e-63
ref|XP_001463948.1|  XRPT, xanthine phosphoribosyltransferas...   244   6e-63
emb|CAO80713.1|  Hypoxanthine-guanine phosphoribosyltransfer...   243   6e-63
ref|ZP_02692325.1|  hypoxanthine phosphoribosyltransferase [...   243   6e-63
ref|YP_001500550.1|  hypoxanthine phosphoribosyltransferase ...   243   7e-63
ref|ZP_03939360.1|  hypoxanthine phosphoribosyltransferase [...   243   8e-63
ref|YP_001504671.1|  hypoxanthine phosphoribosyltransferase ...   243   8e-63
ref|YP_248814.1|  hypoxanthine-guanine phosphoribosyltransfe...   243   9e-63
ref|YP_048119.1|  hypoxanthine phosphoribosyltransferase [Ac...   243   9e-63
ref|ZP_03991579.1|  hypoxanthine phosphoribosyltransferase [...   243   1e-62
ref|ZP_01791303.1|  hypoxanthine-guanine phosphoribosyltrans...   242   1e-62
ref|YP_001647433.1|  hypoxanthine phosphoribosyltransferase ...   242   1e-62
ref|YP_001089202.1|  putative phosphoribosyltransferase [Clo...   242   1e-62
ref|NP_847264.1|  hypoxanthine-guanine phosphoribosyltransfe...   242   1e-62
ref|ZP_03823286.1|  hypoxanthine phosphoribosyltransferase [...   242   2e-62
ref|YP_001293064.1|  hypoxanthine-guanine phosphoribosyltran...   242   2e-62
ref|YP_718674.1|  hypoxanthine phosphoribosyltransferase (HP...   242   2e-62
ref|YP_001717770.1|  hypoxanthine phosphoribosyltransferase ...   242   2e-62
ref|ZP_02083316.1|  hypothetical protein CLOBOL_00837 [Clost...   241   2e-62
ref|ZP_01747148.1|  hypoxanthine phosphoribosyltransferase [...   241   3e-62
ref|NP_245058.1|  hypoxanthine-guanine phosphoribosyltransfe...   241   3e-62
ref|ZP_03952458.1|  hypoxanthine phosphoribosyltransferase [...   241   3e-62
ref|YP_087875.1|  hypoxanthine-guanine phosphoribosyltransfe...   241   3e-62
ref|NP_981268.1|  hypoxanthine-guanine phosphoribosyltransfe...   241   4e-62
ref|NP_834515.1|  hypoxanthine-guanine phosphoribosyltransfe...   241   4e-62
ref|NP_603195.1|  Hypoxanthine-guanine phosphoribosyltransfe...   240   5e-62
ref|YP_038863.1|  hypoxanthine-guanine phosphoribosyltransfe...   240   5e-62
ref|YP_002817623.1|  hypoxanthine phosphoribosyltransferase ...   240   7e-62
gb|EEJ83385.1|  hypoxanthine phosphoribosyltransferase [Kyto...   240   7e-62
ref|YP_001376683.1|  hypoxanthine phosphoribosyltransferase ...   240   8e-62
ref|NP_387949.1|  hypoxanthine-guanine phosphoribosyltransfe...   240   8e-62
ref|ZP_00143803.1|  Hypoxanthine-guanine phosphoribosyltrans...   239   9e-62
ref|YP_145914.1|  hypoxanthine-guanine phosphoribosyltransfe...   239   9e-62
ref|ZP_02255942.1|  hypoxanthine-guanine phosphoribosyltrans...   239   9e-62
ref|ZP_03891750.1|  hypoxanthine phosphoribosyltransferase [...   239   1e-61
Sequences not found previously or not previously below threshold:

ref|ZP_02836636.1|  hypoxanthine phosphoribosyltransferase [...   257   4e-67
ref|YP_945962.1|  hypoxanthine phosphoribosyltransferase [Ar...   257   5e-67
ref|YP_646612.1|  hypoxanthine phosphoribosyltransferase [Ye...   256   1e-66
ref|YP_829651.1|  hypoxanthine phosphoribosyltransferase [Ar...   256   1e-66
ref|ZP_02044194.1|  hypothetical protein ACTODO_01053 [Actin...   255   2e-66
ref|ZP_00821598.1|  COG0634: Hypoxanthine-guanine phosphorib...   254   4e-66
ref|ZP_01066590.1|  hypoxanthine-guanine phosphoribosyltrans...   253   8e-66
ref|ZP_00831594.1|  COG0634: Hypoxanthine-guanine phosphorib...   253   9e-66
ref|ZP_00992731.1|  hypoxanthine-guanine phosphoribosyltrans...   249   1e-64
ref|YP_001855782.1|  hypoxanthine phosphoribosyltransferase ...   249   1e-64
ref|YP_268483.1|  hypoxanthine-guanine phosphoribosyltransfe...   247   6e-64
ref|ZP_01074449.1|  hypoxanthine-guanine phosphoribosyltrans...   244   4e-63
ref|ZP_03935989.1|  hypoxanthine phosphoribosyltransferase [...   242   2e-62
ref|YP_001140676.1|  hypoxanthine phosphoribosyltransferase ...   241   4e-62
ref|YP_926648.1|  Hypoxanthine phosphoribosyltransferase [Sh...   239   1e-61
Searching..................................................done Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|XP_822397.1|  hypoxanthine-guanine phosphoribosyltransfe...   311   2e-83
ref|ZP_01666882.1|  hypoxanthine phosphoribosyltransferase [...   301   3e-80
ref|YP_001274703.1|  hypoxanthine phosphoribosyltransferase ...   298   2e-79
ref|YP_001113711.1|  hypoxanthine phosphoribosyltransferase ...   297   5e-79
ref|ZP_01514399.1|  hypoxanthine phosphoribosyltransferase [...   296   8e-79
gb|EEJ98066.1|  hypoxanthine phosphoribosyltransferase [Ther...   296   9e-79
ref|YP_359913.1|  hypoxanthine phosphoribosyltransferase [Ca...   295   2e-78
ref|NP_469596.1|  fusion protein, N-terminal part similar to...   295   2e-78
ref|NP_463750.1|  fusion protein, N-terminal part similar to...   294   4e-78
ref|YP_012840.1|  conserved hypothetical protein/hypoxanthin...   294   4e-78
ref|ZP_01926199.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   294   4e-78
ref|ZP_02686823.1|  hypothetical protein LmonFSL_00295 [List...   294   4e-78
ref|ZP_01928838.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   294   4e-78
ref|ZP_02276207.1|  hypothetical protein LmonFS_00952 [Liste...   294   4e-78
ref|ZP_00230936.1|  conserved hypothetical protein/hypoxanth...   293   5e-78
ref|ZP_01942347.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   293   6e-78
ref|YP_848383.1|  conserved hypothetical/hypoxanthine phosph...   291   4e-77
ref|YP_002769603.1|  hypoxanthine-guanine phosphoribosyltran...   290   5e-77
ref|NP_627611.1|  hypoxanthine phosphoribosyltransferase [St...   289   7e-77
ref|NP_825842.1|  hypoxanthine phosphoribosyltransferase [St...   289   1e-76
ref|ZP_03924809.1|  hypoxanthine phosphoribosyltransferase [...   288   3e-76
ref|YP_001213102.1|  hypoxanthine-guanine phosphoribosyltran...   287   4e-76
ref|YP_001256007.1|  hypoxanthine phosphoribosyltransferase ...   287   5e-76
ref|NP_814058.1|  hypoxanthine-guanine phosphoribosyltransfe...   286   6e-76
ref|ZP_02091227.1|  hypothetical protein FAEPRAM212_01498 [F...   286   6e-76
ref|ZP_02330217.1|  hypothetical protein Plarl_21636 [Paenib...   286   7e-76
ref|ZP_02618270.1|  hypoxanthine phosphoribosyltransferase [...   286   8e-76
ref|YP_001430999.1|  hypoxanthine phosphoribosyltransferase ...   286   8e-76
ref|ZP_02037643.1|  hypothetical protein BACCAP_03261 [Bacte...   286   8e-76
ref|YP_644942.1|  hypoxanthine phosphoribosyltransferase [Ru...   286   8e-76
ref|YP_001825599.1|  putative hypoxanthine phosphoribosyltra...   286   1e-75
ref|ZP_02581448.1|  hypoxanthine phosphoribosyltransferase [...   285   1e-75
ref|ZP_02993965.1|  hypothetical protein CLOSPO_01067 [Clost...   285   2e-75
ref|ZP_00741717.1|  Hypoxanthine-guanine phosphoribosyltrans...   285   2e-75
ref|YP_001512894.1|  hypoxanthine phosphoribosyltransferase ...   284   3e-75
ref|YP_001642956.1|  hypoxanthine phosphoribosyltransferase ...   284   3e-75
ref|YP_001485312.1|  hypoxanthine phosphoribosyltransferase ...   284   3e-75
ref|ZP_02849796.1|  hypoxanthine phosphoribosyltransferase [...   284   3e-75
ref|YP_001695855.1|  Hypoxanthine-guanine phosphoribosyltran...   284   4e-75
ref|ZP_03922784.1|  hypoxanthine phosphoribosyltransferase [...   284   5e-75
ref|ZP_00603444.1|  Hypoxanthine phosphoribosyl transferase ...   283   5e-75
ref|ZP_04009409.1|  hypoxanthine-guanine phosphoribosyltrans...   283   5e-75
ref|NP_842632.1|  hypoxanthine-guanine phosphoribosyltransfe...   283   5e-75
ref|ZP_02525183.1|  hypoxanthine phosphoribosyltransferase [...   283   5e-75
ref|YP_001373429.1|  hypoxanthine phosphoribosyltransferase ...   283   6e-75
ref|YP_001539489.1|  hypoxanthine phosphoribosyltransferase ...   283   6e-75
ref|YP_001320712.1|  hypoxanthine phosphoribosyltransferase ...   283   6e-75
ref|ZP_03982713.1|  Hypoxanthine phosphoribosyltransferase [...   283   7e-75
ref|YP_536242.1|  Hypoxanthine-guanine phosphoribosyltransfe...   283   9e-75
ref|ZP_01725398.1|  hypoxanthine-guanine phosphoribosyltrans...   282   1e-74
ref|ZP_02263469.1|  hypoxanthine phosphoribosyltransferase [...   282   1e-74
ref|YP_001626350.1|  hypoxanthine-guanine phosphoribosyltran...   282   2e-74
ref|ZP_02281563.1|  hypothetical protein LmonL_01842 [Lister...   281   2e-74
ref|YP_290952.1|  hypoxanthine phosphoribosyl transferase [T...   281   2e-74
ref|YP_001161115.1|  hypoxanthine phosphoribosyltransferase ...   281   2e-74
ref|ZP_03927309.1|  hypoxanthine phosphoribosyltransferase [...   281   2e-74
ref|NP_240950.1|  hypoxanthine-guanine phosphoribosyltransfe...   281   2e-74
ref|NP_829966.1|  hypoxanthine-guanine phosphoribosyltransfe...   281   3e-74
ref|ZP_02836636.1|  hypoxanthine phosphoribosyltransferase [...   281   3e-74
ref|YP_173609.1|  hypoxanthine-guanine phosphoribosyltransfe...   280   5e-74
ref|YP_945962.1|  hypoxanthine phosphoribosyltransferase [Ar...   280   5e-74
ref|ZP_02044194.1|  hypothetical protein ACTODO_01053 [Actin...   280   5e-74
ref|YP_877129.1|  hypoxanthine phosphoribosyltransferase [Cl...   280   6e-74
ref|ZP_02185480.1|  hypoxanthine-guanine phosphoribosyltrans...   279   7e-74
ref|ZP_00379834.1|  COG0634: Hypoxanthine-guanine phosphorib...   279   8e-74
ref|ZP_02278787.1|  hypothetical protein LmonF_02357 [Lister...   279   8e-74
ref|ZP_03856335.1|  hypoxanthine phosphoribosyltransferase [...   279   9e-74
ref|YP_829651.1|  hypoxanthine phosphoribosyltransferase [Ar...   279   1e-73
ref|ZP_02951334.1|  hypoxanthine phosphoribosyltransferase [...   279   1e-73
ref|ZP_01950602.1|  hypoxanthine phosphoribosyltransferase [...   277   4e-73
ref|ZP_00994139.1|  putative hypoxanthine phosphoribosyltran...   277   6e-73
ref|ZP_02643856.1|  hypoxanthine phosphoribosyltransferase [...   277   6e-73
ref|ZP_03826612.1|  hypoxanthine-guanine phosphoribosyltrans...   276   7e-73
ref|ZP_03833725.1|  hypoxanthine-guanine phosphoribosyltrans...   276   7e-73
ref|YP_697159.1|  hypoxanthine phosphoribosyltransferase [Cl...   276   8e-73
ref|NP_563387.1|  hypoxanthine-guanine phosphoribosyltransfe...   276   8e-73
ref|ZP_00832718.1|  COG0634: Hypoxanthine-guanine phosphorib...   276   9e-73
ref|ZP_03868259.1|  hypoxanthine phosphoribosyltransferase [...   276   9e-73
ref|YP_001635640.1|  hypoxanthine phosphoribosyltransferase ...   276   9e-73
ref|YP_138556.1|  hypoxanthine-guanine phosphoribosyltransfe...   276   9e-73
ref|YP_001360283.1|  hypoxanthine phosphoribosyltransferase ...   276   1e-72
ref|NP_230235.1|  hypoxanthine-guanine phosphoribosyltransfe...   276   1e-72
ref|YP_001678694.1|  hypoxanthine phosphoribosyltransferase ...   276   1e-72
ref|NP_780915.1|  hypoxanthine-guanine phosphoribosyltransfe...   276   1e-72
emb|CAG76226.1|  hypoxanthine phosphoribosyltransferase [Erw...   276   1e-72
ref|ZP_01189486.1|  Hypoxanthine phosphoribosyl transferase ...   276   1e-72
ref|YP_051417.2|  hypoxanthine-guanine phosphoribosyltransfe...   275   1e-72
ref|YP_001855782.1|  hypoxanthine phosphoribosyltransferase ...   275   1e-72
gb|AAB41678.1|  hypoxanthine-guanine phosphoribosyltransferase    275   2e-72
ref|ZP_01236067.1|  hypoxanthine-guanine phosphoribosyltrans...   275   2e-72
ref|ZP_03994351.1|  hypoxanthine phosphoribosyltransferase [...   275   2e-72
ref|ZP_00826602.1|  COG0634: Hypoxanthine-guanine phosphorib...   275   2e-72
pdb|1PZM|A  Chain A, Crystal Structure Of Hgprt-Ase From Lei...   275   2e-72
ref|NP_406870.1|  hypoxanthine-guanine phosphoribosyltransfe...   275   2e-72
ref|YP_652817.1|  hypoxanthine phosphoribosyltransferase [Ye...   275   2e-72
ref|NP_668114.2|  hypoxanthine-guanine phosphoribosyltransfe...   275   2e-72
ref|YP_646612.1|  hypoxanthine phosphoribosyltransferase [Ye...   275   2e-72
ref|XP_001463947.1|  HGPRT,hypoxanthine-guanine phosphoribos...   274   2e-72
ref|NP_687051.1|  hypoxanthine-guanine phosphoribosyltransfe...   274   2e-72
ref|ZP_03910773.1|  hypoxanthine phosphoribosyltransferase [...   274   3e-72
ref|ZP_01481302.1|  hypothetical protein VchoR_02002821 [Vib...   274   3e-72
ref|ZP_03813362.1|  hypoxanthine phosphoribosyltransferase [...   274   3e-72
ref|YP_520172.1|  hypothetical protein DSY3939 [Desulfitobac...   274   3e-72
ref|ZP_01160633.1|  hypoxanthine-guanine phosphoribosyltrans...   274   3e-72
ref|YP_001906795.1|  Hypoxanthine phosphoribosyltransferase ...   274   3e-72
ref|ZP_02444150.1|  hypothetical protein ANACOL_03471 [Anaer...   274   4e-72
ref|YP_699727.1|  hypoxanthine phosphoribosyltransferase [Cl...   274   4e-72
emb|CAG21486.1|  putative hypoxanthine ribosyl transferase [...   274   4e-72
ref|NP_935562.1|  hypoxanthine-guanine phosphoribosyltransfe...   274   5e-72
ref|ZP_03958058.1|  hypoxanthine-guanine phosphoribosyltrans...   273   5e-72
ref|ZP_01129459.1|  hypoxanthine phosphoribosyltransferase [...   273   5e-72
ref|YP_001333823.1|  hypoxanthine-guanine phosphoribosyltran...   273   5e-72
ref|YP_807706.1|  Hypoxanthine-guanine phosphoribosyltransfe...   273   6e-72
ref|ZP_01992529.1|  hypoxanthine phosphoribosyltransferase [...   273   6e-72
ref|YP_396211.1|  Hypoxanthine phosphoribosyltranferase [Lac...   273   7e-72
ref|NP_798894.1|  hypoxanthine-guanine phosphoribosyltransfe...   273   7e-72
ref|YP_069264.1|  hypoxanthine-guanine phosphoribosyltransfe...   273   7e-72
ref|ZP_01815583.1|  hypoxanthine-guanine phosphoribosyltrans...   273   7e-72
ref|YP_001402308.1|  hypoxanthine phosphoribosyltransferase ...   273   8e-72
ref|ZP_00821598.1|  COG0634: Hypoxanthine-guanine phosphorib...   273   8e-72
ref|ZP_02919438.1|  hypothetical protein STRINF_00277 [Strep...   273   8e-72
ref|YP_001557268.1|  hypoxanthine phosphoribosyltransferase ...   273   8e-72
ref|YP_074329.1|  hypoxanthine-guanine phosphoribosyltransfe...   273   9e-72
ref|ZP_02081126.1|  hypothetical protein CLOLEP_02599 [Clost...   273   9e-72
ref|NP_690999.1|  hypoxanthine phosphoribosyltransferase [Oc...   273   9e-72
ref|ZP_03845145.1|  hypoxanthine-guanine phosphoribosyltrans...   273   9e-72
ref|NP_720499.1|  hypoxanthine-guanine phosphoribosyltransfe...   273   1e-71
ref|YP_131288.2|  hypoxanthine-guanine phosphoribosyltransfe...   273   1e-71
ref|ZP_01220020.1|  hypoxanthine-guanine phosphoribosyltrans...   272   1e-71
ref|ZP_01262549.1|  hypoxanthine-guanine phosphoribosyltrans...   272   1e-71
ref|ZP_01988476.1|  hypoxanthine phosphoribosyltransferase [...   272   1e-71
ref|YP_001480221.1|  hypoxanthine phosphoribosyltransferase ...   272   1e-71
dbj|BAF43658.1|  hypoxanthine ribosyl transferase [Photobact...   272   1e-71
ref|ZP_03856512.1|  hypoxanthine phosphoribosyltransferase [...   272   2e-71
ref|YP_205559.1|  hypoxanthine phosphoribosyltransferase [Vi...   271   2e-71
ref|ZP_00831594.1|  COG0634: Hypoxanthine-guanine phosphorib...   271   2e-71
dbj|BAF43662.1|  hypoxanthine ribosyl transferase [Vibrio fi...   271   2e-71
ref|XP_001683025.1|  hypoxanthine-guanine phosphoribosyltran...   271   2e-71
ref|XP_001691549.1|  hypothetical protein CHLREDRAFT_145152 ...   271   2e-71
sp|P18134|HPRT_VIBHA  Hypoxanthine phosphoribosyltransferase...   271   2e-71
ref|YP_001574409.1|  hypoxanthine phosphoribosyltransferase ...   271   2e-71
ref|YP_921672.1|  hypoxanthine phosphoribosyltransferase [No...   271   3e-71
ref|ZP_01066590.1|  hypoxanthine-guanine phosphoribosyltrans...   271   3e-71
ref|YP_493197.1|  hypoxanthine phosphoribosyltransferase [St...   271   3e-71
ref|YP_001586484.1|  hypothetical protein SPAB_00209 [Salmon...   271   4e-71
ref|YP_001221583.1|  hypothetical protein CMM_0843 [Clavibac...   271   4e-71
gb|AAX64076.1|  hypoxanthine phosphoribosyltransferase [Salm...   271   4e-71
ref|YP_001439265.1|  hypothetical protein ESA_03207 [Enterob...   271   4e-71
ref|NP_371034.1|  hypoxanthine-guanine phosphoribosyltransfe...   270   5e-71
ref|YP_001708886.1|  putative hypoxanthine phosphoribosyltra...   270   5e-71
ref|YP_062949.1|  hypoxanthine phosphoribosyltransferase [Le...   270   5e-71
ref|ZP_01995978.1|  hypothetical protein DORLON_01976 [Dorea...   270   6e-71
ref|XP_001564804.1|  hypoxanthine-guanine phosphoribosyltran...   270   6e-71
ref|YP_001545794.1|  hypoxanthine phosphoribosyltransferase ...   270   7e-71
ref|ZP_02991800.1|  hypoxanthine phosphoribosyltransferase [...   269   9e-71
ref|YP_001812555.1|  hypoxanthine phosphoribosyltransferase ...   269   9e-71
ref|YP_001307245.1|  hypoxanthine phosphoribosyltransferase ...   269   9e-71
ref|YP_149518.1|  hypoxanthine-guanine phosphoribosyltransfe...   269   9e-71
ref|YP_687706.1|  hypoxanthine phosphoribosyltransferase [Sh...   269   9e-71
ref|ZP_01825459.1|  hypoxanthine phosphoribosyltransferase [...   269   1e-70
ref|YP_001504671.1|  hypoxanthine phosphoribosyltransferase ...   269   1e-70
ref|ZP_02685950.1|  hypothetical protein Salmentericaenteric...   269   1e-70
ref|NP_459175.1|  hypoxanthine-guanine phosphoribosyltransfe...   269   1e-70
ref|NP_344565.1|  hypoxanthine-guanine phosphoribosyltransfe...   269   2e-70
ref|NP_454783.1|  hypoxanthine-guanine phosphoribosyltransfe...   268   2e-70
ref|ZP_02348869.1|  hypothetical protein Sententeri_03139 [S...   268   2e-70
ref|YP_001175411.1|  hypoxanthine phosphoribosyltransferase ...   268   2e-70
ref|NP_349799.1|  Hypoxanthine-guanine phosphoribosyltransfe...   268   2e-70
ref|YP_001843036.1|  hypoxanthine-guanine phosphoribosyltran...   268   2e-70
ref|ZP_02653366.1|  hypothetical protein Sententeric_20357 [...   268   2e-70
ref|YP_001884418.1|  hypoxanthine phosphoribosyltransferase ...   268   2e-70
ref|ZP_03986123.1|  hypoxanthine phosphoribosyltransferase [...   268   2e-70
ref|YP_001034033.1|  Hypoxanthine guanine phosphoribosyltran...   268   2e-70
ref|ZP_02042278.1|  hypothetical protein RUMGNA_03077 [Rumin...   268   2e-70
ref|YP_001451359.1|  hypoxanthine phosphoribosyltransferase ...   268   2e-70
ref|YP_001571814.1|  hypothetical protein SARI_02824 [Salmon...   268   3e-70
ref|YP_254416.1|  putative hypoxanthine-guanine phosphoribos...   268   3e-70
ref|ZP_03860374.1|  hypoxanthine phosphoribosyltransferase [...   268   3e-70
ref|ZP_02288498.1|  hypothetical protein LmonocyFSL_01672 [L...   268   3e-70
ref|ZP_02832830.1|  hypothetical protein Salentericaenterica...   268   3e-70
ref|ZP_01896236.1|  hypoxanthine-guanine phosphoribosyltrans...   268   4e-70
ref|ZP_02943585.1|  hypoxanthine phosphoribosyltransferase [...   267   4e-70
ref|YP_001916267.1|  hypoxanthine phosphoribosyltransferase ...   267   4e-70
ref|YP_002806730.1|  hypoxanthine-guanine phosphoribosyltran...   267   4e-70
emb|CAE13159.1|  unnamed protein product [Photorhabdus lumin...   267   5e-70
ref|ZP_02340312.1|  hypothetical protein Sentent_15771 [Salm...   267   5e-70
ref|ZP_03894492.1|  hypoxanthine phosphoribosyltransferase [...   267   5e-70
ref|YP_539179.1|  hypoxanthine phosphoribosyltransferase [Es...   267   6e-70
ref|XP_816916.1|  hypoxanthine-guanine phosphoribosyltransfe...   267   6e-70
ref|ZP_03835281.1|  hypothetical protein CATC2_04748 [Citrob...   267   6e-70
ref|ZP_00992731.1|  hypoxanthine-guanine phosphoribosyltrans...   266   6e-70
ref|NP_928203.2|  hypoxanthine-guanine phosphoribosyltransfe...   266   6e-70
ref|NP_308156.2|  hypoxanthine-guanine phosphoribosyltransfe...   266   7e-70
ref|ZP_00134029.2|  COG0634: Hypoxanthine-guanine phosphorib...   266   7e-70
ref|ZP_02903074.1|  hypoxanthine phosphoribosyltransferase [...   266   7e-70
ref|YP_001919611.1|  hypoxanthine phosphoribosyltransferase ...   266   7e-70
ref|YP_309162.2|  hypoxanthine phosphoribosyltransferase [Sh...   266   7e-70
ref|ZP_00718322.1|  COG0634: Hypoxanthine-guanine phosphorib...   266   7e-70
gb|EEH95076.1|  hypoxanthine-guanine phosphoribosyltransfera...   266   1e-69
ref|YP_001726475.1|  hypoxanthine phosphoribosyltransferase ...   266   1e-69
ref|YP_302336.1|  putative hypoxanthine-guanine phosphoribos...   266   1e-69
gb|AAZ86927.1|  hypoxanthine phosphoribosyltransferase [Shig...   266   1e-69
ref|YP_794711.1|  Hypoxanthine-guanine phosphoribosyltransfe...   266   1e-69
ref|YP_001454762.1|  hypothetical protein CKO_03242 [Citroba...   266   1e-69
pdb|1TC2|A  Chain A, Ternary Substrate Complex Of The Hypoxa...   266   1e-69
ref|ZP_04002769.1|  hypoxanthine phosphoribosyltransferase [...   266   1e-69
ref|NP_765828.1|  hypoxanthine-guanine phosphoribosyltransfe...   265   1e-69
pdb|1R3U|A  Chain A, Crystal Structure Of Hypoxanthine-Guani...   265   1e-69
ref|YP_735273.1|  hypoxanthine phosphoribosyltransferase [Sh...   265   1e-69
ref|YP_001053387.1|  yypoxanthine phosphoribosyltransferase ...   265   1e-69
pdb|1TC1|A  Chain A, A 1.4 Angstrom Crystal Structure For Th...   265   2e-69
ref|ZP_01869538.1|  hypoxanthine-guanine phosphoribosyltrans...   265   2e-69
ref|YP_001742252.1|  hypoxanthine phosphoribosyltransferase ...   265   2e-69
ref|NP_928199.1|  hypoxanthine-guanine phosphoribosyltransfe...   265   2e-69
pdb|1P17|A  Chain A, Hypoxanthine Phosphoribosyltransferase ...   264   2e-69
sp|Q27541|HPRT_CRIFA  Hypoxanthine-guanine phosphoribosyltra...   264   3e-69
ref|ZP_02210445.1|  hypothetical protein CLOBAR_02853 [Clost...   264   3e-69
ref|ZP_01704836.1|  hypoxanthine phosphoribosyltransferase [...   264   3e-69
ref|NP_784322.1|  hypoxanthine-guanine phosphoribosyltransfe...   264   3e-69
ref|ZP_01965205.1|  hypothetical protein RUMOBE_02936 [Rumin...   264   3e-69
ref|NP_623929.1|  Hypoxanthine-guanine phosphoribosyltransfe...   264   3e-69
ref|XP_813396.1|  hypoxanthine-guanine phosphoribosyltransfe...   264   3e-69
ref|NP_439311.1|  hypoxanthine-guanine phosphoribosyltransfe...   264   4e-69
pdb|1G9S|A  Chain A, Crystal Structure Of A Complex Between ...   264   5e-69
ref|ZP_01841716.1|  hypoxanthine phosphoribosyltransferase [...   263   6e-69
ref|ZP_01783677.1|  hypoxanthine-guanine phosphoribosyltrans...   263   6e-69
ref|YP_001672979.1|  hypoxanthine phosphoribosyltransferase ...   263   6e-69
ref|ZP_02431763.1|  hypothetical protein CLOSCI_01994 [Clost...   263   7e-69
ref|YP_964712.1|  hypoxanthine phosphoribosyltransferase [Sh...   263   7e-69
pdb|1I14|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   263   7e-69
ref|YP_001197388.1|  Hypoxanthine-guanine phosphoribosyltran...   263   8e-69
pdb|1I0L|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   263   8e-69
ref|ZP_03939360.1|  hypoxanthine phosphoribosyltransferase [...   263   8e-69
ref|YP_001095267.1|  hypoxanthine phosphoribosyltransferase ...   263   9e-69
ref|YP_001664305.1|  hypoxanthine phosphoribosyltransferase ...   263   1e-68
ref|ZP_00155585.2|  COG0634: Hypoxanthine-guanine phosphorib...   263   1e-68
ref|ZP_00874757.1|  Hypoxanthine phosphoribosyl transferase ...   263   1e-68
pdb|1I0I|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   263   1e-68
ref|NP_719339.1|  hypoxanthine phosphoribosyltransferase [Sh...   262   1e-68
ref|ZP_01788849.1|  hypoxanthine-guanine phosphoribosyltrans...   262   1e-68
ref|ZP_02478331.1|  hypoxanthine phosphoribosyltransferase [...   262   1e-68
ref|YP_001717770.1|  hypoxanthine phosphoribosyltransferase ...   262   2e-68
pdb|1I13|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   261   2e-68
ref|YP_145914.1|  hypoxanthine-guanine phosphoribosyltransfe...   261   2e-68
ref|ZP_01967905.1|  hypothetical protein RUMTOR_01471 [Rumin...   261   3e-68
ref|ZP_01772665.1|  Hypothetical protein COLAER_01679 [Colli...   261   3e-68
ref|YP_268483.1|  hypoxanthine-guanine phosphoribosyltransfe...   261   3e-68
ref|ZP_03952458.1|  hypoxanthine phosphoribosyltransferase [...   261   3e-68
ref|YP_054976.1|  putative hypoxanthine phosphoribosyltransf...   261   4e-68
ref|XP_638364.1|  hypoxanthine phosphoribosyltransferase [Di...   261   4e-68
gb|EEJ83385.1|  hypoxanthine phosphoribosyltransferase [Kyto...   261   4e-68
ref|YP_001049118.1|  hypoxanthine phosphoribosyltransferase ...   260   5e-68
ref|ZP_00156993.1|  COG0634: Hypoxanthine-guanine phosphorib...   260   5e-68
ref|YP_001124193.1|  Hypoxanthine-guanine phosphoribosyltran...   260   5e-68
ref|YP_645559.1|  hypoxanthine phosphoribosyltransferase [Ru...   260   6e-68
ref|YP_248814.1|  hypoxanthine-guanine phosphoribosyltransfe...   260   6e-68
ref|XP_816917.1|  hypoxanthine-guanine phosphoribosyltransfe...   260   6e-68
ref|ZP_03935989.1|  hypoxanthine phosphoribosyltransferase [...   260   7e-68
ref|YP_001140676.1|  hypoxanthine phosphoribosyltransferase ...   259   8e-68
ref|XP_813397.1|  hypoxanthine-guanine phosphoribosyltransfe...   259   9e-68
gb|AAD50967.1|AF170105_2  xanthine phosphoribosyltransferase...   259   9e-68
ref|XP_001564805.1|  xanthine phosphoribosyltransferase [Lei...   259   9e-68
ref|YP_001500550.1|  hypoxanthine phosphoribosyltransferase ...   259   9e-68
ref|YP_001331506.1|  hypoxanthine phosphoribosyltransferase ...   259   9e-68
ref|NP_387949.1|  hypoxanthine-guanine phosphoribosyltransfe...   259   1e-67
ref|ZP_02692325.1|  hypoxanthine phosphoribosyltransferase [...   259   1e-67
ref|ZP_01791303.1|  hypoxanthine-guanine phosphoribosyltrans...   259   1e-67
ref|ZP_03942372.1|  hypoxanthine phosphoribosyltransferase [...   259   1e-67
ref|YP_087875.1|  hypoxanthine-guanine phosphoribosyltransfe...   259   1e-67
ref|ZP_01074449.1|  hypoxanthine-guanine phosphoribosyltrans...   259   1e-67
ref|YP_048119.1|  hypoxanthine phosphoribosyltransferase [Ac...   259   1e-67
gb|ABY56069.1|  hypoxanthine phosphoribosyltransferase [uncu...   259   1e-67
ref|XP_001683026.1|  xanthine phosphoribosyltransferase [Lei...   259   1e-67
ref|YP_001293064.1|  hypoxanthine-guanine phosphoribosyltran...   259   2e-67
ref|YP_718674.1|  hypoxanthine phosphoribosyltransferase (HP...   259   2e-67
pdb|2GEB|A  Chain A, Crystal Structure Of The Thermoanaeroba...   258   2e-67
ref|YP_001715593.1|  hypoxanthine phosphoribosyltransferase ...   258   2e-67
ref|ZP_02961601.2|  hypothetical protein PROSTU_03641 [Provi...   258   2e-67
ref|ZP_03991579.1|  hypoxanthine phosphoribosyltransferase [...   258   2e-67
ref|ZP_03891750.1|  hypoxanthine phosphoribosyltransferase [...   258   2e-67
emb|CAO80713.1|  Hypoxanthine-guanine phosphoribosyltransfer...   258   4e-67
ref|YP_926648.1|  Hypoxanthine phosphoribosyltransferase [Sh...   257   4e-67
ref|YP_001708669.1|  hypoxanthine phosphoribosyltransferase ...   257   4e-67
ref|ZP_02914467.1|  hypoxanthine phosphoribosyltransferase [...   257   5e-67
ref|ZP_03823286.1|  hypoxanthine phosphoribosyltransferase [...   257   5e-67
ref|YP_858016.1|  hypoxanthine phosphoribosyltransferase [Ae...   257   5e-67
gb|EEK06649.1|  hypoxanthine phosphoribosyltransferase [Brac...   257   6e-67
ref|NP_245058.1|  hypoxanthine-guanine phosphoribosyltransfe...   257   6e-67
ref|ZP_01747148.1|  hypoxanthine phosphoribosyltransferase [...   257   6e-67
ref|ZP_01173368.1|  hypoxanthine-guanine phosphoribosyltrans...   256   7e-67
ref|YP_001475642.1|  Hypoxanthine phosphoribosyltransferase ...   256   8e-67
ref|YP_001419748.1|  HprT [Bacillus amyloliquefaciens FZB42]...   256   1e-66
ref|ZP_02169053.1|  Hypoxanthine phosphoribosyltransferase [...   256   1e-66
ref|ZP_02083316.1|  hypothetical protein CLOBOL_00837 [Clost...   256   1e-66
ref|NP_847264.1|  hypoxanthine-guanine phosphoribosyltransfe...   256   1e-66
ref|ZP_03958961.1|  hypoxanthine phosphoribosyltransferase [...   255   2e-66
ref|YP_001762172.1|  hypoxanthine phosphoribosyltransferase ...   255   2e-66
ref|ZP_03884487.1|  hypoxanthine phosphoribosyltransferase [...   255   2e-66
ref|YP_001647433.1|  hypoxanthine phosphoribosyltransferase ...   255   2e-66
ref|YP_001167250.1|  hypoxanthine phosphoribosyltransferase ...   255   2e-66
Sequences not found previously or not previously below threshold:

  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF excluding environmental samples
  from WGS projects
    Posted date:  May 23, 2008  5:56 PM
  Number of letters in database: 883,778,997
  Number of sequences in database:  2,617,685
  
  Database: /host/Blast/data/nr_perl/nr.01
    Posted date:  May 23, 2008  5:54 PM
  Number of letters in database: 976,759,346
  Number of sequences in database:  2,761,413
  
  Database: /host/Blast/data/nr_perl/nr.02
    Posted date:  May 23, 2008  5:48 PM
  Number of letters in database: 374,670,760
  Number of sequences in database:  1,165,270
  
  Database: /host/Blast/data/nr_perl/nr.03
    Posted date:  Apr 28, 2009  5:40 PM
  Number of letters in database: 114,943,120
  Number of sequences in database:  354,819
  
Lambda     K      H
   0.312    0.183    0.610 

Lambda     K      H
   0.267   0.0561    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,816,373,975
Number of Sequences: 6899187
Number of extensions: 306019745
Number of successful extensions: 658830
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 5309
Number of HSP's successfully gapped in prelim test: 2314
Number of HSP's that attempted gapping in prelim test: 642350
Number of HSP's gapped (non-prelim): 8122
length of query: 234
length of database: 2,350,152,223
effective HSP length: 130
effective length of query: 104
effective length of database: 1,453,257,913
effective search space: 151138822952
effective search space used: 151138822952
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (20.9 bits)
S2: 77 (33.8 bits)