BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= XP_822405.1__[Trypanosoma_brucei]
         (210 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           6,899,187 sequences; 2,350,152,223 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_822405.1|  hypoxanthine-guanine phosphoribosyltransfe...   414   e-114
ref|XP_822398.1|  hypoxanthine-guanine phosphoribosyltransfe...   408   e-112
ref|XP_816916.1|  hypoxanthine-guanine phosphoribosyltransfe...   215   2e-54
pdb|1P17|A  Chain A, Hypoxanthine Phosphoribosyltransferase ...   215   2e-54
pdb|1TC2|A  Chain A, Ternary Substrate Complex Of The Hypoxa...   214   5e-54
pdb|1TC1|A  Chain A, A 1.4 Angstrom Crystal Structure For Th...   213   5e-54
ref|XP_813396.1|  hypoxanthine-guanine phosphoribosyltransfe...   213   6e-54
pdb|1I0L|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   211   2e-53
pdb|1I14|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   211   3e-53
pdb|1I0I|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   211   4e-53
pdb|1I13|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   210   6e-53
sp|Q27541|HPRT_CRIFA  Hypoxanthine-guanine phosphoribosyltra...   169   2e-40
ref|XP_001463947.1|  HGPRT,hypoxanthine-guanine phosphoribos...   162   2e-38
ref|XP_001683025.1|  hypoxanthine-guanine phosphoribosyltran...   161   3e-38
ref|XP_822397.1|  hypoxanthine-guanine phosphoribosyltransfe...   159   9e-38
ref|XP_001564804.1|  hypoxanthine-guanine phosphoribosyltran...   159   2e-37
pdb|1PZM|A  Chain A, Crystal Structure Of Hgprt-Ase From Lei...   157   3e-37
gb|ABE47510.1|  hypoxanthine-guanine phosphoribosyltransfera...   154   5e-36
gb|ABE47508.1|  hypoxanthine-guanine phosphoribosyltransfera...   153   9e-36
gb|ABE47509.1|  hypoxanthine-guanine phosphoribosyltransfera...   152   1e-35
ref|XP_813397.1|  hypoxanthine-guanine phosphoribosyltransfe...   148   3e-34
ref|XP_816917.1|  hypoxanthine-guanine phosphoribosyltransfe...   147   4e-34
ref|XP_001564805.1|  xanthine phosphoribosyltransferase [Lei...   145   1e-33
gb|AAD50967.1|AF170105_2  xanthine phosphoribosyltransferase...   138   3e-31
gb|AAF61462.1|AF139722_1  hypoxanthine-guanine phosphoribosy...   137   6e-31
ref|XP_001683026.1|  xanthine phosphoribosyltransferase [Lei...   136   1e-30
ref|XP_001463948.1|  XRPT, xanthine phosphoribosyltransferas...   135   2e-30
ref|ZP_02177337.1|  hypoxanthine-guanine phosphoribosyltrans...   135   2e-30
ref|YP_001513548.1|  hypoxanthine phosphoribosyltransferase ...   133   9e-30
ref|YP_001213102.1|  hypoxanthine-guanine phosphoribosyltran...   133   9e-30
ref|YP_001113711.1|  hypoxanthine phosphoribosyltransferase ...   132   1e-29
ref|YP_912357.1|  hypoxanthine phosphoribosyltransferase [Ch...   132   2e-29
ref|YP_460761.1|  hypoxanthine-guanine phosphoribosyltransfe...   132   2e-29
ref|ZP_00530669.1|  Hypoxanthine phosphoribosyl transferase ...   131   2e-29
ref|YP_001319457.1|  hypoxanthine phosphoribosyltransferase ...   131   2e-29
emb|CAO80713.1|  Hypoxanthine-guanine phosphoribosyltransfer...   131   3e-29
ref|YP_001161115.1|  hypoxanthine phosphoribosyltransferase ...   130   4e-29
ref|YP_001539489.1|  hypoxanthine phosphoribosyltransferase ...   130   5e-29
ref|YP_001512894.1|  hypoxanthine phosphoribosyltransferase ...   130   8e-29
ref|YP_074329.1|  hypoxanthine-guanine phosphoribosyltransfe...   129   1e-28
ref|ZP_01666882.1|  hypoxanthine phosphoribosyltransferase [...   129   2e-28
ref|YP_001916267.1|  hypoxanthine phosphoribosyltransferase ...   129   2e-28
ref|NP_782785.1|  hypoxanthine-guanine phosphoribosyltransfe...   129   2e-28
ref|NP_784322.1|  hypoxanthine-guanine phosphoribosyltransfe...   128   2e-28
ref|ZP_02037643.1|  hypothetical protein BACCAP_03261 [Bacte...   128   2e-28
ref|YP_002769603.1|  hypoxanthine-guanine phosphoribosyltran...   127   4e-28
ref|ZP_02091227.1|  hypothetical protein FAEPRAM212_01498 [F...   127   4e-28
ref|ZP_02951334.1|  hypoxanthine phosphoribosyltransferase [...   127   7e-28
ref|ZP_03958961.1|  hypoxanthine phosphoribosyltransferase [...   127   7e-28
ref|YP_001678694.1|  hypoxanthine phosphoribosyltransferase ...   126   9e-28
ref|YP_001089748.1|  hypoxanthine phosphoribosyltransferase ...   126   1e-27
ref|YP_921672.1|  hypoxanthine phosphoribosyltransferase [No...   125   1e-27
ref|ZP_01802750.1|  hypothetical protein CdifQ_04003751 [Clo...   125   3e-27
ref|YP_645559.1|  hypoxanthine phosphoribosyltransferase [Ru...   124   3e-27
ref|ZP_02581448.1|  hypoxanthine phosphoribosyltransferase [...   124   3e-27
ref|ZP_00741717.1|  Hypoxanthine-guanine phosphoribosyltrans...   124   3e-27
ref|ZP_00994139.1|  putative hypoxanthine phosphoribosyltran...   124   3e-27
ref|NP_825842.1|  hypoxanthine phosphoribosyltransferase [St...   124   4e-27
ref|YP_909271.1|  hypoxanthine-guanine phosphoribosyltransfe...   124   4e-27
ref|ZP_03860374.1|  hypoxanthine phosphoribosyltransferase [...   124   4e-27
ref|XP_638364.1|  hypoxanthine phosphoribosyltransferase [Di...   124   4e-27
ref|NP_439311.1|  hypoxanthine-guanine phosphoribosyltransfe...   124   4e-27
ref|NP_245058.1|  hypoxanthine-guanine phosphoribosyltransfe...   124   5e-27
ref|XP_001691549.1|  hypothetical protein CHLREDRAFT_145152 ...   124   5e-27
ref|ZP_01783677.1|  hypoxanthine-guanine phosphoribosyltrans...   124   5e-27
ref|ZP_02525183.1|  hypoxanthine phosphoribosyltransferase [...   124   6e-27
ref|ZP_02478331.1|  hypoxanthine phosphoribosyltransferase [...   124   6e-27
ref|NP_814058.1|  hypoxanthine-guanine phosphoribosyltransfe...   124   6e-27
ref|YP_375425.1|  Hypoxanthine phosphoribosyl transferase [P...   123   7e-27
ref|YP_001311294.1|  hypoxanthine phosphoribosyltransferase ...   123   7e-27
ref|YP_001293064.1|  hypoxanthine-guanine phosphoribosyltran...   123   8e-27
ref|YP_001320712.1|  hypoxanthine phosphoribosyltransferase ...   123   8e-27
ref|ZP_00155585.2|  COG0634: Hypoxanthine-guanine phosphorib...   123   1e-26
ref|YP_248814.1|  hypoxanthine-guanine phosphoribosyltransfe...   123   1e-26
ref|NP_627611.1|  hypoxanthine phosphoribosyltransferase [St...   123   1e-26
ref|YP_001642956.1|  hypoxanthine phosphoribosyltransferase ...   123   1e-26
ref|ZP_00592291.1|  Hypoxanthine phosphoribosyl transferase ...   122   1e-26
ref|ZP_00603444.1|  Hypoxanthine phosphoribosyl transferase ...   122   1e-26
ref|ZP_02330217.1|  hypothetical protein Plarl_21636 [Paenib...   122   1e-26
ref|ZP_01788849.1|  hypoxanthine-guanine phosphoribosyltrans...   122   2e-26
ref|NP_829966.1|  hypoxanthine-guanine phosphoribosyltransfe...   122   2e-26
ref|ZP_00156993.1|  COG0634: Hypoxanthine-guanine phosphorib...   122   2e-26
ref|ZP_02686823.1|  hypothetical protein LmonFSL_00295 [List...   122   2e-26
ref|NP_213381.1|  hypoxanthine-guanine phosphoribosyltransfe...   122   2e-26
ref|ZP_02276207.1|  hypothetical protein LmonFS_00952 [Liste...   122   2e-26
ref|YP_001373429.1|  hypoxanthine phosphoribosyltransferase ...   122   2e-26
ref|NP_463750.1|  fusion protein, N-terminal part similar to...   122   2e-26
ref|ZP_00230936.1|  conserved hypothetical protein/hypoxanth...   122   2e-26
ref|ZP_01928838.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   122   2e-26
ref|YP_012840.1|  conserved hypothetical protein/hypoxanthin...   122   2e-26
ref|ZP_01926199.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   122   2e-26
ref|ZP_02263469.1|  hypoxanthine phosphoribosyltransferase [...   122   2e-26
ref|NP_842632.1|  hypoxanthine-guanine phosphoribosyltransfe...   122   2e-26
ref|ZP_01942347.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   122   2e-26
ref|NP_469596.1|  fusion protein, N-terminal part similar to...   122   2e-26
ref|ZP_00134029.2|  COG0634: Hypoxanthine-guanine phosphorib...   121   3e-26
ref|YP_001053387.1|  yypoxanthine phosphoribosyltransferase ...   121   3e-26
ref|ZP_02916961.1|  hypothetical protein BIFDEN_00221 [Bifid...   121   3e-26
ref|YP_001825599.1|  putative hypoxanthine phosphoribosyltra...   121   3e-26
ref|ZP_03982713.1|  Hypoxanthine phosphoribosyltransferase [...   121   3e-26
ref|ZP_02949925.1|  hypoxanthine phosphoribosyltransferase [...   121   3e-26
gb|AAS02076.1|  hypoxanthine-guanine phosphoribosyltransfera...   121   3e-26
ref|YP_001695855.1|  Hypoxanthine-guanine phosphoribosyltran...   121   3e-26
ref|YP_848383.1|  conserved hypothetical/hypoxanthine phosph...   121   3e-26
gb|EEJ98066.1|  hypoxanthine phosphoribosyltransferase [Ther...   121   3e-26
ref|ZP_01791303.1|  hypoxanthine-guanine phosphoribosyltrans...   121   4e-26
ref|ZP_01129459.1|  hypoxanthine phosphoribosyltransferase [...   121   4e-26
ref|ZP_03958058.1|  hypoxanthine-guanine phosphoribosyltrans...   121   4e-26
ref|NP_780915.1|  hypoxanthine-guanine phosphoribosyltransfe...   121   4e-26
ref|YP_054976.1|  putative hypoxanthine phosphoribosyltransf...   120   4e-26
ref|YP_699727.1|  hypoxanthine phosphoribosyltransferase [Cl...   120   5e-26
ref|ZP_02643856.1|  hypoxanthine phosphoribosyltransferase [...   120   5e-26
ref|ZP_01189486.1|  Hypoxanthine phosphoribosyl transferase ...   120   5e-26
ref|ZP_01725398.1|  hypoxanthine-guanine phosphoribosyltrans...   120   6e-26
ref|NP_344565.1|  hypoxanthine-guanine phosphoribosyltransfe...   120   6e-26
ref|YP_644942.1|  hypoxanthine phosphoribosyltransferase [Ru...   120   7e-26
ref|ZP_03856512.1|  hypoxanthine phosphoribosyltransferase [...   120   7e-26
ref|ZP_03916784.1|  hypoxanthine phosphoribosyltransferase [...   120   7e-26
ref|NP_563387.1|  hypoxanthine-guanine phosphoribosyltransfe...   120   7e-26
ref|YP_001038649.1|  hypoxanthine phosphoribosyltransferase ...   120   8e-26
ref|YP_520172.1|  hypothetical protein DSY3939 [Desulfitobac...   120   8e-26
ref|YP_001708886.1|  putative hypoxanthine phosphoribosyltra...   120   8e-26
ref|YP_001920333.1|  hypoxanthine phosphoribosyltransferase ...   120   9e-26
ref|ZP_01825459.1|  hypoxanthine phosphoribosyltransferase [...   119   1e-25
ref|YP_697159.1|  hypoxanthine phosphoribosyltransferase [Cl...   119   1e-25
ref|ZP_02094407.1|  hypothetical protein PEPMIC_01173 [Pepto...   119   1e-25
ref|YP_794711.1|  Hypoxanthine-guanine phosphoribosyltransfe...   119   1e-25
ref|YP_359913.1|  hypoxanthine phosphoribosyltransferase [Ca...   119   1e-25
ref|ZP_02994748.1|  hypothetical protein CLOSPO_01867 [Clost...   119   1e-25
ref|ZP_03937742.1|  hypoxanthine phosphoribosyltransferase [...   119   1e-25
gb|ABC86778.1|  hypoxanthine-guanine phosphoribosyltransfera...   119   2e-25
ref|ZP_03939360.1|  hypoxanthine phosphoribosyltransferase [...   119   2e-25
ref|ZP_03952458.1|  hypoxanthine phosphoribosyltransferase [...   119   2e-25
ref|YP_001344116.1|  hypoxanthine phosphoribosyltransferase ...   119   2e-25
gb|EEJ83385.1|  hypoxanthine phosphoribosyltransferase [Kyto...   119   2e-25
ref|ZP_02849796.1|  hypoxanthine phosphoribosyltransferase [...   118   2e-25
ref|YP_001485312.1|  hypoxanthine phosphoribosyltransferase ...   118   2e-25
ref|ZP_00143803.1|  Hypoxanthine-guanine phosphoribosyltrans...   118   2e-25
ref|YP_290952.1|  hypoxanthine phosphoribosyl transferase [T...   118   2e-25
ref|ZP_03942372.1|  hypoxanthine phosphoribosyltransferase [...   118   2e-25
ref|ZP_02185480.1|  hypoxanthine-guanine phosphoribosyltrans...   118   2e-25
ref|YP_001221583.1|  hypothetical protein CMM_0843 [Clavibac...   118   3e-25
ref|YP_001885202.1|  hypoxanthine phosphoribosyltransferase ...   118   3e-25
ref|YP_062949.1|  hypoxanthine phosphoribosyltransferase [Le...   118   3e-25
ref|ZP_01574690.1|  hypoxanthine phosphoribosyltransferase [...   118   3e-25
ref|ZP_03994351.1|  hypoxanthine phosphoribosyltransferase [...   118   3e-25
ref|ZP_02278787.1|  hypothetical protein LmonF_02357 [Lister...   118   3e-25
ref|ZP_01747148.1|  hypoxanthine phosphoribosyltransferase [...   118   3e-25
ref|ZP_02210776.1|  hypothetical protein CLOBAR_00343 [Clost...   117   5e-25
ref|ZP_03894492.1|  hypoxanthine phosphoribosyltransferase [...   117   5e-25
ref|YP_001919611.1|  hypoxanthine phosphoribosyltransferase ...   117   5e-25
dbj|BAF43662.1|  hypoxanthine ribosyl transferase [Vibrio fi...   117   5e-25
ref|NP_603195.1|  Hypoxanthine-guanine phosphoribosyltransfe...   117   6e-25
ref|YP_805009.1|  Hypoxanthine-guanine phosphoribosyltransfe...   117   6e-25
ref|ZP_02272383.1|  Hypoxanthine-guanine phosphoribosyltrans...   117   6e-25
ref|YP_867088.1|  hypoxanthine phosphoribosyltransferase [Ma...   117   6e-25
ref|NP_662412.1|  hypoxanthine-guanine phosphoribosyltransfe...   116   8e-25
ref|ZP_03845145.1|  hypoxanthine-guanine phosphoribosyltrans...   116   8e-25
ref|YP_001728691.1|  Hypoxanthine phosphoribosyltransferase ...   116   9e-25
ref|YP_001884418.1|  hypoxanthine phosphoribosyltransferase ...   116   9e-25
ref|NP_787717.1|  hypoxanthine-guanine phosphoribosyltransfe...   116   9e-25
ref|YP_205559.1|  hypoxanthine phosphoribosyltransferase [Vi...   116   1e-24
gb|EEH97466.1|  hypoxanthine-guanine phosphoribosyltransfera...   116   1e-24
ref|ZP_03826612.1|  hypoxanthine-guanine phosphoribosyltrans...   116   1e-24
emb|CAE13159.1|  unnamed protein product [Photorhabdus lumin...   116   1e-24
ref|YP_001843036.1|  hypoxanthine-guanine phosphoribosyltran...   116   1e-24
ref|ZP_02991800.1|  hypoxanthine phosphoribosyltransferase [...   115   1e-24
ref|YP_001715593.1|  hypoxanthine phosphoribosyltransferase ...   115   1e-24
ref|NP_928203.2|  hypoxanthine-guanine phosphoribosyltransfe...   115   1e-24
emb|CAG76226.1|  hypoxanthine phosphoribosyltransferase [Erw...   115   1e-24
emb|CAN75448.1|  hypothetical protein [Vitis vinifera] >gi|1...   115   2e-24
ref|YP_051417.2|  hypoxanthine-guanine phosphoribosyltransfe...   115   2e-24
ref|ZP_04019022.1|  hypoxanthine phosphoribosyltransferase [...   115   2e-24
ref|ZP_02444150.1|  hypothetical protein ANACOL_03471 [Anaer...   115   2e-24
ref|NP_834515.1|  hypoxanthine-guanine phosphoribosyltransfe...   115   2e-24
ref|YP_001545794.1|  hypoxanthine phosphoribosyltransferase ...   115   2e-24
ref|YP_396211.1|  Hypoxanthine phosphoribosyltranferase [Lac...   115   2e-24
ref|ZP_02522268.1|  hypoxanthine-guanine phosphoribosyltrans...   115   2e-24
ref|ZP_03924809.1|  hypoxanthine phosphoribosyltransferase [...   115   2e-24
ref|YP_877129.1|  hypoxanthine phosphoribosyltransferase [Cl...   115   2e-24
ref|NP_789114.1|  hypoxanthine phosphoribosyltransferase [Tr...   115   2e-24
ref|ZP_01950602.1|  hypoxanthine phosphoribosyltransferase [...   115   2e-24
ref|NP_847264.1|  hypoxanthine-guanine phosphoribosyltransfe...   115   2e-24
ref|YP_001333823.1|  hypoxanthine-guanine phosphoribosyltran...   115   2e-24
ref|XP_001753497.1|  predicted protein [Physcomitrella paten...   115   2e-24
ref|YP_038863.1|  hypoxanthine-guanine phosphoribosyltransfe...   115   2e-24
ref|NP_928199.1|  hypoxanthine-guanine phosphoribosyltransfe...   115   2e-24
ref|YP_001692114.1|  hypoxanthine-guanine phosphoribosyltran...   115   2e-24
ref|YP_138556.1|  hypoxanthine-guanine phosphoribosyltransfe...   115   3e-24
ref|ZP_03922784.1|  hypoxanthine phosphoribosyltransferase [...   115   3e-24
ref|YP_699238.1|  hypoxanthine phosphoribosyltransferase [Cl...   115   3e-24
ref|YP_807706.1|  Hypoxanthine-guanine phosphoribosyltransfe...   115   3e-24
ref|ZP_02992594.1|  hypoxanthine phosphoribosyltransferase [...   115   3e-24
ref|NP_349799.1|  Hypoxanthine-guanine phosphoribosyltransfe...   115   3e-24
ref|YP_001270874.1|  hypoxanthine phosphoribosyltransferase ...   114   3e-24
ref|YP_001708669.1|  hypoxanthine phosphoribosyltransferase ...   114   3e-24
dbj|BAA34253.1|  hypoxanthine-guanine phosphoribosyl-transfe...   114   3e-24
ref|ZP_01772665.1|  Hypothetical protein COLAER_01679 [Colli...   114   3e-24
ref|YP_002753307.1|  hypoxanthine phosphoribosyltransferase ...   114   3e-24
ref|ZP_00121459.2|  COG0634: Hypoxanthine-guanine phosphorib...   114   3e-24
ref|ZP_01273646.1|  Hypoxanthine phosphoribosyl transferase ...   114   4e-24
ref|ZP_03976626.1|  hypoxanthine phosphoribosyltransferase [...   114   4e-24
ref|ZP_03908779.1|  hypoxanthine phosphoribosyltransferase [...   114   4e-24
ref|ZP_02081126.1|  hypothetical protein CLOLEP_02599 [Clost...   114   4e-24
ref|NP_696832.1|  hypoxanthine-guanine phosphoribosyltransfe...   114   4e-24
ref|ZP_03833725.1|  hypoxanthine-guanine phosphoribosyltrans...   114   5e-24
ref|YP_001647433.1|  hypoxanthine phosphoribosyltransferase ...   114   5e-24
ref|YP_002817623.1|  hypoxanthine phosphoribosyltransferase ...   114   5e-24
ref|ZP_01753405.1|  hypoxanthine phosphoribosyltransferase [...   114   5e-24
ref|ZP_01003606.1|  hypoxanthine phosphoribosyltransferase [...   114   5e-24
ref|YP_718674.1|  hypoxanthine phosphoribosyltransferase (HP...   114   5e-24
ref|ZP_02832830.1|  hypothetical protein Salentericaenterica...   114   5e-24
ref|YP_001906795.1|  Hypoxanthine phosphoribosyltransferase ...   114   6e-24
ref|ZP_02943585.1|  hypoxanthine phosphoribosyltransferase [...   114   6e-24
ref|ZP_01903422.1|  hypoxanthine phosphoribosyltransferase [...   113   7e-24
ref|YP_001820494.1|  hypoxanthine phosphoribosyltransferase ...   113   8e-24
sp|P37171|HPRT_RHOCA  Hypoxanthine-guanine phosphoribosyltra...   113   8e-24
ref|YP_001360283.1|  hypoxanthine phosphoribosyltransferase ...   113   8e-24
ref|ZP_03974729.1|  hypoxanthine phosphoribosyltransferase [...   113   8e-24
ref|YP_001586484.1|  hypothetical protein SPAB_00209 [Salmon...   113   9e-24
ref|ZP_01742691.1|  Hypoxanthine-guanine phosphoribosyltrans...   113   9e-24
ref|YP_613363.1|  hypoxanthine phosphoribosyltransferase [Si...   113   9e-24
ref|NP_981268.1|  hypoxanthine-guanine phosphoribosyltransfe...   113   1e-23
ref|YP_001376683.1|  hypoxanthine phosphoribosyltransferase ...   113   1e-23
ref|NP_230235.1|  hypoxanthine-guanine phosphoribosyltransfe...   113   1e-23
ref|YP_001480221.1|  hypoxanthine phosphoribosyltransferase ...   113   1e-23
ref|YP_945962.1|  hypoxanthine phosphoribosyltransferase [Ar...   113   1e-23
ref|YP_001439265.1|  hypothetical protein ESA_03207 [Enterob...   113   1e-23
sp|P57291|HPRT_BUCAI  Hypoxanthine phosphoribosyltransferase...   112   1e-23
ref|ZP_02255942.1|  hypoxanthine-guanine phosphoribosyltrans...   112   1e-23
gb|ABL85241.1|  putative hypoxanthine-guanine phosphoribosyl...   112   1e-23
ref|ZP_01156250.1|  hypoxanthine phosphoribosyltransferase [...   112   1e-23
ref|NP_240026.1|  hypoxanthine phosphoribosyltransferase [Bu...   112   1e-23
gb|AAX64076.1|  hypoxanthine phosphoribosyltransferase [Salm...   112   1e-23
ref|ZP_02281563.1|  hypothetical protein LmonL_01842 [Lister...   112   1e-23
ref|ZP_01514399.1|  hypoxanthine phosphoribosyltransferase [...   112   1e-23
ref|ZP_02737445.1|  hypoxanthine-guanine phosphoribosyltrans...   112   1e-23
ref|YP_682988.1|  hypoxanthine phosphoribosyltransferase [Ro...   112   1e-23
ref|ZP_03856335.1|  hypoxanthine phosphoribosyltransferase [...   112   1e-23
ref|YP_001451359.1|  hypoxanthine phosphoribosyltransferase ...   112   1e-23
ref|ZP_02965931.1|  hypoxanthine phosphoribosyltransferase [...   112   1e-23
ref|NP_660543.1|  hypoxanthine phosphoribosyltransferase [Bu...   112   1e-23
ref|YP_001307245.1|  hypoxanthine phosphoribosyltransferase ...   112   2e-23
ref|YP_001256007.1|  hypoxanthine phosphoribosyltransferase ...   112   2e-23
ref|YP_001626350.1|  hypoxanthine-guanine phosphoribosyltran...   112   2e-23
ref|NP_454783.1|  hypoxanthine-guanine phosphoribosyltransfe...   112   2e-23
ref|ZP_02836636.1|  hypoxanthine phosphoribosyltransferase [...   112   2e-23
ref|ZP_01056939.1|  hypoxanthine phosphoribosyltransferase [...   112   2e-23
ref|ZP_02685950.1|  hypothetical protein Salmentericaenteric...   112   2e-23
ref|ZP_02143764.1|  hypoxanthine phosphoribosyltransferase [...   112   2e-23
ref|NP_459175.1|  hypoxanthine-guanine phosphoribosyltransfe...   112   2e-23
ref|ZP_03910773.1|  hypoxanthine phosphoribosyltransferase [...   112   2e-23
ref|YP_087875.1|  hypoxanthine-guanine phosphoribosyltransfe...   112   2e-23
ref|ZP_02139177.1|  hypoxanthine phosphoribosyltransferase [...   112   2e-23
ref|ZP_02148512.1|  hypoxanthine phosphoribosyltransferase [...   112   2e-23
ref|ZP_00999316.1|  hypoxanthine phosphoribosyltransferase [...   112   2e-23
ref|ZP_01313104.1|  hypoxanthine phosphoribosyltransferase [...   112   2e-23
gb|EEK06649.1|  hypoxanthine phosphoribosyltransferase [Brac...   112   2e-23
ref|YP_001571814.1|  hypothetical protein SARI_02824 [Salmon...   111   3e-23
emb|CAJ74742.1|  similar to hypoxanthine-guanine-xanthine ph...   111   3e-23
ref|YP_829651.1|  hypoxanthine phosphoribosyltransferase [Ar...   111   3e-23
gb|ABK94285.1|  unknown [Populus trichocarpa]                     111   3e-23
ref|YP_149518.1|  hypoxanthine-guanine phosphoribosyltransfe...   111   3e-23
ref|ZP_02653366.1|  hypothetical protein Sententeric_20357 [...   111   3e-23
ref|ZP_00874757.1|  Hypoxanthine phosphoribosyl transferase ...   111   3e-23
ref|ZP_02348869.1|  hypothetical protein Sententeri_03139 [S...   111   3e-23
ref|ZP_01896236.1|  hypoxanthine-guanine phosphoribosyltrans...   111   3e-23
ref|ZP_02634287.1|  hypoxanthine phosphoribosyltransferase [...   111   3e-23
ref|ZP_01481302.1|  hypothetical protein VchoR_02002821 [Vib...   111   3e-23
ref|YP_001717770.1|  hypoxanthine phosphoribosyltransferase ...   111   3e-23
ref|ZP_02423670.1|  hypothetical protein EUBSIR_02544 [Eubac...   111   3e-23
ref|ZP_02094616.1|  hypothetical protein PEPMIC_01383 [Pepto...   111   3e-23
ref|YP_754454.1|  Hypoxanthine phosphoribosyltransferase [Sy...   111   3e-23
ref|ZP_03929414.1|  hypoxanthine phosphoribosyltransferase [...   111   3e-23
ref|ZP_02153583.1|  hypoxanthine phosphoribosyltransferase [...   111   4e-23
ref|ZP_01442330.1|  hypoxanthine phosphoribosyltransferase [...   111   4e-23
ref|YP_254416.1|  putative hypoxanthine-guanine phosphoribos...   111   4e-23
ref|NP_562876.1|  hypoxanthine-guanine phosphoribosyltransfe...   111   4e-23
ref|NP_925736.1|  hypoxanthine phosphoribosyltransferase [Gl...   111   4e-23
ref|YP_536242.1|  Hypoxanthine-guanine phosphoribosyltransfe...   111   4e-23
ref|ZP_02044194.1|  hypothetical protein ACTODO_01053 [Actin...   110   4e-23
ref|ZP_02340312.1|  hypothetical protein Sentent_15771 [Salm...   110   4e-23
ref|NP_935562.1|  hypoxanthine-guanine phosphoribosyltransfe...   110   4e-23
sp|P18134|HPRT_VIBHA  Hypoxanthine phosphoribosyltransferase...   110   5e-23
ref|ZP_02961601.2|  hypothetical protein PROSTU_03641 [Provi...   110   5e-23
gb|EAY56375.1|  hypoxanthine-guanine phosphoribosyltransfera...   110   5e-23
ref|YP_605052.1|  hypoxanthine phosphoribosyltransferase [De...   110   5e-23
ref|ZP_01988476.1|  hypoxanthine phosphoribosyltransferase [...   110   5e-23
ref|ZP_04009409.1|  hypoxanthine-guanine phosphoribosyltrans...   110   5e-23
ref|ZP_02025766.1|  hypothetical protein EUBVEN_01019 [Eubac...   110   5e-23
ref|ZP_01014815.1|  Hypoxanthine-guanine phosphoribosyltrans...   110   6e-23
ref|YP_510172.1|  hypoxanthine phosphoribosyltransferase [Ja...   110   6e-23
ref|YP_173609.1|  hypoxanthine-guanine phosphoribosyltransfe...   110   6e-23
ref|ZP_02618270.1|  hypoxanthine phosphoribosyltransferase [...   110   6e-23
ref|YP_001034033.1|  Hypoxanthine guanine phosphoribosyltran...   110   7e-23
ref|ZP_02692325.1|  hypoxanthine phosphoribosyltransferase [...   110   7e-23
gb|ACO65791.1|  predicted protein [Micromonas sp. RCC299]         110   7e-23
ref|ZP_01448574.1|  hypoxanthine phosphoribosyltransferase [...   110   7e-23
ref|YP_001214180.1|  hypoxanthine phosphoribosyltransferase ...   110   7e-23
ref|YP_307841.1|  hypoxanthine phosphoribosyltransferase [De...   110   7e-23
>ref|XP_822405.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
 gb|EAN77577.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
          Length = 210

 Score =  414 bits (1065), Expect = e-114,   Method: Composition-based stats.
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT
Sbjct: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL
Sbjct: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE
Sbjct: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180

Query: 181 VRDVVILKPSVYETWGKELERRKAAVKAKL 210
           VRDVVILKPSVYETWGKELERRKAAVKAKL
Sbjct: 181 VRDVVILKPSVYETWGKELERRKAAVKAKL 210
>ref|XP_822398.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
 sp|Q07010|HPRT_TRYBB Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase)
 gb|AAA16328.1| hypoxanthine-guanine phosphoribosyltransferase
 gb|EAN77570.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
          Length = 210

 Score =  408 bits (1048), Expect = e-112,   Method: Composition-based stats.
 Identities = 205/209 (98%), Positives = 208/209 (99%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLV+VSVL+GSFVFT
Sbjct: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVIVSVLKGSFVFT 60

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL
Sbjct: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE
Sbjct: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180

Query: 181 VRDVVILKPSVYETWGKELERRKAAVKAK 209
           VRDVVILKPSVYETWGKELERRKAA +AK
Sbjct: 181 VRDVVILKPSVYETWGKELERRKAAGEAK 209
>ref|XP_816916.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi strain CL Brener]
 gb|EAN95065.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi]
          Length = 241

 Score =  215 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 104/201 (51%), Positives = 145/201 (72%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 24  EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 83

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+DTALTL  +
Sbjct: 84  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYL 143

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 144 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 203

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY       ++++ A+
Sbjct: 204 VLRPEVYAEREAARQKKQRAI 224
>pdb|1P17|A Chain A, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P17|B Chain B, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P17|C Chain C, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P17|D Chain D, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P18|A Chain A, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Ternary Substrates Complex
 pdb|1P18|B Chain B, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Ternary Substrates Complex
          Length = 221

 Score =  215 bits (547), Expect = 2e-54,   Method: Composition-based stats.
 Identities = 105/201 (52%), Positives = 145/201 (72%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVLRGSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLRGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+DTALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY       ++++ A+
Sbjct: 184 VLRPEVYAEREAARQKKQRAI 204
>pdb|1TC2|A Chain A, Ternary Substrate Complex Of The Hypoxanthine
           Phosphoribosyltransferase From Trypanosoma Cruzi
 pdb|1TC2|B Chain B, Ternary Substrate Complex Of The Hypoxanthine
           Phosphoribosyltransferase From Trypanosoma Cruzi
 pdb|1P19|A Chain A, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
 pdb|1P19|B Chain B, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
 pdb|1P19|C Chain C, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
 pdb|1P19|D Chain D, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
          Length = 221

 Score =  214 bits (544), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 104/201 (51%), Positives = 145/201 (72%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+DTALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY       ++++ A+
Sbjct: 184 VLRPEVYAEREAARQKKQRAI 204
>pdb|1TC1|A Chain A, A 1.4 Angstrom Crystal Structure For The Hypoxanthine
           Phosphoribosyltransferase Of Trypanosoma Cruzi
 pdb|1TC1|B Chain B, A 1.4 Angstrom Crystal Structure For The Hypoxanthine
           Phosphoribosyltransferase Of Trypanosoma Cruzi
          Length = 220

 Score =  213 bits (543), Expect = 5e-54,   Method: Composition-based stats.
 Identities = 104/201 (51%), Positives = 145/201 (72%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 3   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 62

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+DTALTL  +
Sbjct: 63  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYL 122

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 123 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 182

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY       ++++ A+
Sbjct: 183 VLRPEVYAEREAARQKKQRAI 203
>ref|XP_813396.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi strain CL Brener]
 gb|AAB46391.1| hypoxanthine-guanine phosphoribosyltransferase
 gb|EAN91545.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi]
          Length = 221

 Score =  213 bits (543), Expect = 6e-54,   Method: Composition-based stats.
 Identities = 104/201 (51%), Positives = 144/201 (71%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR+  VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIMEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+DTALTL  +
Sbjct: 64  ALSDFNVPVRMEFICVSSYGEGVTSSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY       ++++ A+
Sbjct: 184 VLRPEVYAEREAARQKKQRAI 204
>pdb|1I0L|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Asparagine
           Mutant
 pdb|1I0L|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Asparagine
           Mutant
          Length = 221

 Score =  211 bits (538), Expect = 2e-53,   Method: Composition-based stats.
 Identities = 102/187 (54%), Positives = 139/187 (74%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI++TALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVNTALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVY 192
           +L+P VY
Sbjct: 184 VLRPEVY 190
>pdb|1I14|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamic
           Acid Mutant
 pdb|1I14|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamic
           Acid Mutant
          Length = 221

 Score =  211 bits (537), Expect = 3e-53,   Method: Composition-based stats.
 Identities = 102/187 (54%), Positives = 139/187 (74%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI++TALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVETALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVY 192
           +L+P VY
Sbjct: 184 VLRPEVY 190
>pdb|1I0I|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamine
           Mutant
 pdb|1I0I|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamine
           Mutant
          Length = 221

 Score =  211 bits (536), Expect = 4e-53,   Method: Composition-based stats.
 Identities = 102/187 (54%), Positives = 138/187 (73%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+ TALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVQTALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVY 192
           +L+P VY
Sbjct: 184 VLRPEVY 190
>pdb|1I13|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Alanine
           Mutant
 pdb|1I13|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Alanine
           Mutant
          Length = 221

 Score =  210 bits (534), Expect = 6e-53,   Method: Composition-based stats.
 Identities = 102/187 (54%), Positives = 138/187 (73%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+ TALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVATALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVY 192
           +L+P VY
Sbjct: 184 VLRPEVY 190
>sp|Q27541|HPRT_CRIFA Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase)
 gb|AAB04164.1| hypoxanthine-guanine phophoribosyltransferase
          Length = 208

 Score =  169 bits (427), Expect = 2e-40,   Method: Composition-based stats.
 Identities = 84/193 (43%), Positives = 128/193 (66%), Gaps = 1/193 (0%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           Y  +   L T+ ++ +     A++IA+DY   NL   ENPL ++ VL+GSF+FTAD+ R 
Sbjct: 17  YPMSCRTLATQEQIWSATAKCAKQIAEDYKQYNLSD-ENPLYLLCVLKGSFMFTADLARF 75

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           L D GVP R+EF+ ASSYG D K+ G V +  D    +  +H+L++EDI+D+A+TL  + 
Sbjct: 76  LCDEGVPVRIEFICASSYGTDVKTSGEVRLLLDVRDPVENRHLLIVEDIVDSAITLEYLK 135

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
             L+  +PAS+KT+V +DKP GRK+  + +Y V  +P+ FV+GYG+D+ ++YRE+RDV +
Sbjct: 136 RFLQAKQPASLKTVVLLDKPSGRKVTLSVDYPVITIPHAFVIGYGMDFAEAYRELRDVCV 195

Query: 187 LKPSVYETWGKEL 199
           LK   YE    +L
Sbjct: 196 LKKEYYEKPASKL 208
>ref|XP_001463947.1| HGPRT,hypoxanthine-guanine phosphoribosynthesis protein [Leishmania
           infantum JPCM5]
 sp|P43152|HPRT_LEIDO Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase)
 gb|AAD50966.1|AF170105_1 hypoxanthine-guanine phosphoribosyltransferase HGPRT [Leishmania
           donovani]
 gb|AAB00074.1| hypoxanthine-guanine phosphoribosyltransferase
 emb|CAM66321.1| HGPRT,hypoxanthine-guanine phosphoribosynthesis protein [Leishmania
           infantum]
          Length = 211

 Score =  162 bits (409), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 79/187 (42%), Positives = 125/187 (66%), Gaps = 1/187 (0%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           Y  +   L T+ ++       A++IA+DY +  L   +NPL ++ VL+GSF+FTAD+ R 
Sbjct: 20  YPMSAHTLVTQEQVWAATAKCAKKIAEDYRSFKLTT-DNPLYLLCVLKGSFIFTADLARF 78

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           L D GVP +VEF+ ASSYG   ++ G+V +  D    +  +H+L++EDI+D+A+TL+ ++
Sbjct: 79  LADEGVPVKVEFICASSYGTGVETSGQVRMLLDVRDSVENRHILIVEDIVDSAITLQYLM 138

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
             +   +PAS+KT+V +DKP GRK+    +Y V  +P+ FV+GYG+DY +SYRE+RD+ +
Sbjct: 139 RFMLAKKPASLKTVVLLDKPSGRKVEVLVDYPVITIPHAFVIGYGMDYAESYRELRDICV 198

Query: 187 LKPSVYE 193
           LK   YE
Sbjct: 199 LKKEYYE 205
>ref|XP_001683025.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania major]
 emb|CAJ04328.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania major]
          Length = 211

 Score =  161 bits (407), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 79/187 (42%), Positives = 124/187 (66%), Gaps = 1/187 (0%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           Y  +   L T+ ++       A++IA+DY +  L    NPL ++ VL+GSF+FTAD+ R 
Sbjct: 20  YPMSAHTLVTQEQVWAATAKCAKKIAEDYRSFKLTT-GNPLYLLCVLKGSFIFTADLARF 78

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           L D GVP +VEF+ ASSYG   ++ G+V +  D    +  +H+L++EDI+D+A+TL+ ++
Sbjct: 79  LADEGVPVKVEFICASSYGTGVETSGQVRMLLDVRDSVENRHILIVEDIVDSAITLQYLM 138

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
             +   +PAS+KT+V +DKP GRK+    +Y V  +P+ FV+GYG+DY +SYRE+RD+ +
Sbjct: 139 RFMLAKKPASLKTVVLLDKPSGRKVEVLVDYPVITIPHAFVIGYGMDYAESYRELRDICV 198

Query: 187 LKPSVYE 193
           LK   YE
Sbjct: 199 LKKEYYE 205
>ref|XP_822397.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
 gb|EAN77569.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma brucei]
          Length = 234

 Score =  159 bits (403), Expect = 9e-38,   Method: Composition-based stats.
 Identities = 89/209 (42%), Positives = 129/209 (61%), Gaps = 17/209 (8%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYS-----------NCNLKPL--ENPLVVVSVL 53
           Y  A SV+ TE+ +H  M+ +AQ +A+ Y            N  L P+  ENPL+++SVL
Sbjct: 27  YPMAESVVATESTIHRSMKEMAQTLANAYKTLKHRDTHNKGNSALAPITDENPLIIISVL 86

Query: 54  RGSFVFTADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGL--CDIRGKHVLV 111
           +GS++FTADMVR LGD G+P  V+F+R +SY   TKS G V V  D L   ++ GKHVL+
Sbjct: 87  KGSYIFTADMVRYLGDCGLPNVVDFIRITSYRGTTKSSGTVQV-LDNLRFTELTGKHVLI 145

Query: 112 LEDILDTALTLREVVDSLKKS-EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGY 170
           +EDI DT  T++ +V+ +++   PAS+K  V +DKPGGR + F  E+V    P  +VVGY
Sbjct: 146 MEDIADTGRTMKLLVEKIRREYRPASLKVCVLVDKPGGRVVDFKPEFVCLTAPTRYVVGY 205

Query: 171 GLDYDQSYREVRDVVILKPSVYETWGKEL 199
           G + +  YR  R V +LKP   + +  +L
Sbjct: 206 GFEVNDRYRNYRHVFVLKPEYAKRYPSKL 234
>ref|XP_001564804.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania
           braziliensis MHOM/BR/75/M2904]
 emb|CAM38879.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania
           braziliensis]
          Length = 211

 Score =  159 bits (401), Expect = 2e-37,   Method: Composition-based stats.
 Identities = 80/186 (43%), Positives = 120/186 (64%), Gaps = 1/186 (0%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           Y  +   + T+ ++       A+ IA DY    L P ENPL ++ VL+GSF+FTAD+ R 
Sbjct: 20  YPMSARTVITQEQVWAATAQCAKTIAQDYEKFKLAP-ENPLYLLCVLKGSFIFTADLARF 78

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           L D GVP RVEF+ ASSYG   ++ G+V +  D    +  +H+L++EDI+D+A+TL+ ++
Sbjct: 79  LADEGVPVRVEFICASSYGEGVETSGQVRMLLDVRDSVEDRHILIVEDIVDSAITLQYLM 138

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
             +    PAS+KT+V +DKP  RK+    +Y +  VP+VFV+GYG+D+ +SYRE+RDV  
Sbjct: 139 RFMLAKRPASLKTVVLLDKPSRRKVKLLVDYPIIRVPDVFVIGYGMDFAESYRELRDVCE 198

Query: 187 LKPSVY 192
           LK   Y
Sbjct: 199 LKKEYY 204
>pdb|1PZM|A Chain A, Crystal Structure Of Hgprt-Ase From Leishmania Tarentolae
           In Complex With Gmp
 pdb|1PZM|B Chain B, Crystal Structure Of Hgprt-Ase From Leishmania Tarentolae
           In Complex With Gmp
          Length = 211

 Score =  157 bits (398), Expect = 3e-37,   Method: Composition-based stats.
 Identities = 77/187 (41%), Positives = 124/187 (66%), Gaps = 1/187 (0%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           Y  +   L T+ ++       A++IA DY + +L   +NPL ++ VL+GSF+FTAD+ R 
Sbjct: 20  YPMSARTLVTQEQVWAATAKCAKKIAADYKDFHLTA-DNPLYLLCVLKGSFIFTADLARF 78

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           L D GVP +VEF+ ASSYG   ++ G+V +  D    +  +H++++EDI+D+A+TL+ ++
Sbjct: 79  LADEGVPVKVEFICASSYGSGVETSGQVRMLLDVRDSVENRHIMLVEDIVDSAITLQYLM 138

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
             +   +PAS+KT+V +DKP GRK+    +Y V  +P  FV+GYG+D+ +SYRE+RD+ +
Sbjct: 139 RFMLAKKPASLKTVVLLDKPSGRKVDVLVDYPVITIPRAFVIGYGMDFAESYRELRDICV 198

Query: 187 LKPSVYE 193
           LK   YE
Sbjct: 199 LKKEYYE 205
>gb|ABE47510.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania
           infantum]
          Length = 168

 Score =  154 bits (388), Expect = 5e-36,   Method: Composition-based stats.
 Identities = 74/161 (45%), Positives = 116/161 (72%), Gaps = 1/161 (0%)

Query: 28  AQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGVPTRVEFLRASSYGHD 87
           A++IA+DY +  L   +NPL ++ VL+GSF+FTAD+ R L D GVP +VEF+ ASSYG  
Sbjct: 6   AKKIAEDYRSFKLTT-DNPLYLLCVLKGSFIFTADLARFLADEGVPVKVEFICASSYGTG 64

Query: 88  TKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPG 147
            ++ G+V +  D    +  +H+L++EDI+D+A+TL+ ++  +   +PAS+KT+V +DKP 
Sbjct: 65  VETSGQVRMLLDVRDSVENRHILIVEDIVDSAITLQYLMRFMLAKKPASLKTVVLLDKPS 124

Query: 148 GRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           GRK+    +Y V  +P+ FV+GYG+DY +SYRE+RD+ +LK
Sbjct: 125 GRKVEVLVDYPVITIPHAFVIGYGMDYAESYRELRDICVLK 165
>gb|ABE47508.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania sp.
           IMT208]
          Length = 168

 Score =  153 bits (386), Expect = 9e-36,   Method: Composition-based stats.
 Identities = 74/161 (45%), Positives = 115/161 (71%), Gaps = 1/161 (0%)

Query: 28  AQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGVPTRVEFLRASSYGHD 87
           A++IA+DY +  L    NPL ++ VL+GSF+FTAD+ R L D GVP +VEF+ ASSYG  
Sbjct: 6   AKKIAEDYRSFKLTTX-NPLYLLCVLKGSFIFTADLARFLADEGVPVKVEFICASSYGTG 64

Query: 88  TKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPG 147
            ++ G+V +  D    +  +H+L++EDI+D+A+TL+ ++  +   +PAS+KT+V +DKP 
Sbjct: 65  VETSGQVRMLLDVRDSVENRHILIVEDIVDSAITLQYLMRFMLAKKPASLKTVVLLDKPS 124

Query: 148 GRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           GRK+    +Y V  +P+ FV+GYG+DY +SYRE+RD+ +LK
Sbjct: 125 GRKVEVLVDYPVITIPHAFVIGYGMDYAESYRELRDICVLK 165
>gb|ABE47509.1| hypoxanthine-guanine phosphoribosyltransferase [Leishmania major]
          Length = 168

 Score =  152 bits (385), Expect = 1e-35,   Method: Composition-based stats.
 Identities = 74/161 (45%), Positives = 115/161 (71%), Gaps = 1/161 (0%)

Query: 28  AQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGVPTRVEFLRASSYGHD 87
           A++IA+DY +  L    NPL ++ VL+GSF+FTAD+ R L D GVP +VEF+ ASSYG  
Sbjct: 6   AKKIAEDYRSFKLTT-GNPLYLLCVLKGSFIFTADLARFLADEGVPVKVEFICASSYGTG 64

Query: 88  TKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKSEPASIKTLVAIDKPG 147
            ++ G+V +  D    +  +H+L++EDI+D+A+TL+ ++  +   +PAS+KT+V +DKP 
Sbjct: 65  VETSGQVRMLLDVRDSVENRHILIVEDIVDSAITLQYLMRFMLAKKPASLKTVVLLDKPS 124

Query: 148 GRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           GRK+    +Y V  +P+ FV+GYG+DY +SYRE+RD+ +LK
Sbjct: 125 GRKVEVLVDYPVITIPHAFVIGYGMDYAESYRELRDICVLK 165
>ref|XP_813397.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi strain CL Brener]
 gb|EAN91546.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi]
          Length = 231

 Score =  148 bits (373), Expect = 3e-34,   Method: Composition-based stats.
 Identities = 78/196 (39%), Positives = 126/196 (64%), Gaps = 14/196 (7%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCN---------LKPL--ENPLVVVSVLRG 55
           Y  A  ++ TE+ +   ++ VA++IAD Y   +         + P+  ENPL+++SVL+G
Sbjct: 27  YPMAEELVATESVIQRSIKAVAKQIADFYRPLSHRDTHGGGGVAPISDENPLIIISVLKG 86

Query: 56  SFVFTADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADG-LCDIRGKHVLVLED 114
           S++FTADMVR LGD+G+P  V+FLR +SY   T S  ++ + A+     +RGKHVL+LED
Sbjct: 87  SYIFTADMVRYLGDYGLPHVVDFLRVASY-RGTSSTNKMQLLAETQFKALRGKHVLILED 145

Query: 115 ILDTALTLREVVDSLKKS-EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLD 173
           I+D+  TLR ++D +++  +PA++K  V  DKPGGR++    ++V   VPN +V+GYG +
Sbjct: 146 IVDSGKTLRYILDKVQREHQPATLKVCVLADKPGGRRVTMQPDFVCLTVPNKYVIGYGFE 205

Query: 174 YDQSYREVRDVVILKP 189
            +  +R  R +  L+P
Sbjct: 206 VNDRFRCFRHIFTLRP 221
>ref|XP_816917.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi strain CL Brener]
 gb|EAN95066.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi]
          Length = 231

 Score =  147 bits (372), Expect = 4e-34,   Method: Composition-based stats.
 Identities = 78/196 (39%), Positives = 126/196 (64%), Gaps = 14/196 (7%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCN---------LKPL--ENPLVVVSVLRG 55
           Y  A  ++ TE+ +   ++ VA++IAD Y   +         + P+  ENPL+++SVL+G
Sbjct: 27  YPMAEELVATESVIQRSIKAVAKQIADFYRPLSHRDTHGGGGVAPISDENPLIIISVLKG 86

Query: 56  SFVFTADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADG-LCDIRGKHVLVLED 114
           S++FTADMVR LGD+G+P  V+FLR +SY   T S  ++ + A+     +RGKHVL+LED
Sbjct: 87  SYIFTADMVRYLGDYGLPHVVDFLRVASY-RGTSSTNKMKLLAETQFKALRGKHVLILED 145

Query: 115 ILDTALTLREVVDSLKKS-EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLD 173
           I+D+  TLR ++D +++  +PA++K  V  DKPGGR++    ++V   VPN +V+GYG +
Sbjct: 146 IVDSGKTLRYILDKVQREHQPATLKVCVLADKPGGRRVTMQPDFVCLTVPNKYVIGYGFE 205

Query: 174 YDQSYREVRDVVILKP 189
            +  +R  R +  L+P
Sbjct: 206 VNDRFRCFRHIFTLRP 221
>ref|XP_001564805.1| xanthine phosphoribosyltransferase [Leishmania braziliensis
           MHOM/BR/75/M2904]
 emb|CAM38880.1| xanthine phosphoribosyltransferase [Leishmania braziliensis]
          Length = 240

 Score =  145 bits (367), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 81/208 (38%), Positives = 130/208 (62%), Gaps = 26/208 (12%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYS-----NCNLKP----------------LE 44
           +Y  A+S++ TE  + ++++ +AQ IA+DY      +C L P                 +
Sbjct: 23  EYPMASSIIATEDVIQSKIKAMAQTIANDYKLLTHRDCRLPPNVATGMETVVSEAPISYD 82

Query: 45  NPLVVVSVLRGSFVFTADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLC-- 102
           NPL++VSVL+GS++FTAD +R LGD G+P  V+F+R +SY   T+S GRV + + GL   
Sbjct: 83  NPLIIVSVLKGSYIFTADFIRYLGDCGLPHVVDFVRLTSYNDGTRSTGRVAMLS-GLKFE 141

Query: 103 DIRGKHVLVLEDILDTALTLREVVDS-LKKSEPASIKTLVAIDK-PGGRKIPFTAEYVVA 160
           ++RGKHVL++ED+ D+  TL  +  S ++K +P SIKTLV ++K    RK+ F  EY   
Sbjct: 142 NLRGKHVLIVEDVCDSGRTLHFLRTSIIEKYQPKSIKTLVMVNKEAAARKVDFEPEYACL 201

Query: 161 DVPNVFVVGYGLDYDQSYREVRDVVILK 188
             PN +++GYG + +  YR++R ++IL+
Sbjct: 202 SSPNKYIIGYGFEVNDRYRDLRHILILR 229
>gb|AAD50967.1|AF170105_2 xanthine phosphoribosyltransferase XPRT [Leishmania donovani]
          Length = 241

 Score =  138 bits (348), Expect = 3e-31,   Method: Composition-based stats.
 Identities = 79/209 (37%), Positives = 126/209 (60%), Gaps = 27/209 (12%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYS-----NCNLKP-----------------L 43
           +Y  A+ ++ TE  + T ++ +A  IA DY      +  L P                  
Sbjct: 23  EYPMASGIVATEDVIQTNIKAMAHTIAKDYKSLSHRDARLSPSTAETAEAAEAAEAPISY 82

Query: 44  ENPLVVVSVLRGSFVFTADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLC- 102
           +NPL+++SVL+GS++FT+D +R LGD G+P  V+F+R +SY   TKS G++ + A GL  
Sbjct: 83  DNPLIIISVLKGSYIFTSDFIRYLGDCGLPHVVDFVRLASYNSGTKSTGQISMLA-GLRF 141

Query: 103 -DIRGKHVLVLEDILDTALTLREVVDS-LKKSEPASIKTLVAIDKP-GGRKIPFTAEYVV 159
            ++RGKHVL++ED+ D+  TLR + D  ++K +P SIKTLV ++K    RK+ F  EY  
Sbjct: 142 ENLRGKHVLIVEDVCDSGRTLRFLRDYIMEKFQPKSIKTLVMVNKEQAARKVDFDPEYFC 201

Query: 160 ADVPNVFVVGYGLDYDQSYREVRDVVILK 188
              PN ++VGYG + +  YR++R ++IL+
Sbjct: 202 LAGPNKYIVGYGFEVNDRYRDLRHILILR 230
>gb|AAF61462.1|AF139722_1 hypoxanthine-guanine phosphoribosyltransferase; HGPRT [Leishmania
           tarentolae]
          Length = 210

 Score =  137 bits (344), Expect = 6e-31,   Method: Composition-based stats.
 Identities = 72/187 (38%), Positives = 117/187 (62%), Gaps = 2/187 (1%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           Y  +   L T+ ++       A++IA DY + +L   +NPL ++ VL+GSF+FTAD+ R 
Sbjct: 20  YPMSARTLVTQEQVWAATAKCAKKIAADYKDFHLTA-DNPLYLLCVLKGSFIFTADLARF 78

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           L D GVP +VEF+ ASSYG   ++ G+V +  D    +  +H++++EDI+D+A+TL+ ++
Sbjct: 79  LADEGVPVKVEFICASSYGSGVETSGQVRMLLDVRDSVENRHIMLVEDIVDSAITLQYLM 138

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
             +   +PAS+KT+V +DKP GRK+    +Y V  +P+ FV+GY   +    R V D+ +
Sbjct: 139 RFMLAKKPASLKTVVLLDKPSGRKVDVLVDYPVITIPHAFVIGYVWTF-ADLRGVPDICV 197

Query: 187 LKPSVYE 193
           LK   YE
Sbjct: 198 LKKEYYE 204
>ref|XP_001683026.1| xanthine phosphoribosyltransferase [Leishmania major]
 emb|CAJ04332.1| xanthine phosphoribosyltransferase [Leishmania major]
          Length = 238

 Score =  136 bits (342), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 77/206 (37%), Positives = 124/206 (60%), Gaps = 24/206 (11%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYS-----NCNLKP--------------LENP 46
           +Y  A+ ++ TE  +   ++ +A  IA DY      +  L P               +NP
Sbjct: 23  EYPMASGIVATEDVIQANIKAMANTIAKDYKSLSHRDVRLSPGTAATAEAAEAPISYDNP 82

Query: 47  LVVVSVLRGSFVFTADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLC--DI 104
           L+++SVL+GS++FT+D +R LGD G+P  V+F+R +SY  DT S G++ + A GL   ++
Sbjct: 83  LIIISVLKGSYIFTSDFIRYLGDCGLPHVVDFVRLASYNSDTTSTGQISMLA-GLRFENL 141

Query: 105 RGKHVLVLEDILDTALTLREVVDS-LKKSEPASIKTLVAIDKP-GGRKIPFTAEYVVADV 162
           RGKHVL++ED+ D+  TLR + D  ++K +P S+KTLV ++K    RK+ F  EY     
Sbjct: 142 RGKHVLIVEDVCDSGRTLRFLRDYIMEKFQPKSVKTLVMVNKEQAARKLDFDPEYFCLAG 201

Query: 163 PNVFVVGYGLDYDQSYREVRDVVILK 188
           PN ++VGYG + +  YR++R + IL+
Sbjct: 202 PNKYIVGYGFEVNDRYRDLRHIFILR 227
>ref|XP_001463948.1| XRPT, xanthine phosphoribosyltransferase [Leishmania infantum
           JPCM5]
 emb|CAM66322.1| XRPT, xanthine phosphoribosyltransferase [Leishmania infantum]
          Length = 216

 Score =  135 bits (341), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 78/205 (38%), Positives = 124/205 (60%), Gaps = 27/205 (13%)

Query: 10  ATSVLFTEAELHTRMRGVAQRIADDYS-----NCNLKP-----------------LENPL 47
           A+ ++ TE  + T ++ +A  IA DY      +  L P                  +NPL
Sbjct: 2   ASGIVATEDVIQTNIKAMAHTIAKDYKSLSHRDARLSPSTAETAEAAEAAEAPISYDNPL 61

Query: 48  VVVSVLRGSFVFTADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLC--DIR 105
           +++SVL+GS++FT+D +R LGD G+P  V+F+R +SY   TKS G++ + A GL   ++R
Sbjct: 62  IIISVLKGSYIFTSDFIRYLGDCGLPHVVDFVRLASYNSGTKSTGQISMLA-GLRFENLR 120

Query: 106 GKHVLVLEDILDTALTLREVVDS-LKKSEPASIKTLVAIDKP-GGRKIPFTAEYVVADVP 163
           GKHVL++ED+ D+  TLR + D  ++K +P SIKTLV ++K    RK+ F  EY     P
Sbjct: 121 GKHVLIVEDVCDSGRTLRFLRDYIMEKFQPKSIKTLVMVNKEQAARKVDFDPEYFCLAGP 180

Query: 164 NVFVVGYGLDYDQSYREVRDVVILK 188
           N ++VGYG + +  YR++R ++IL+
Sbjct: 181 NKYIVGYGFEVNDRYRDLRHILILR 205
>ref|ZP_02177337.1| hypoxanthine-guanine phosphoribosyltransferase [Hydrogenivirga sp.
           128-5-R1-1]
 gb|EDP75878.1| hypoxanthine-guanine phosphoribosyltransferase [Hydrogenivirga sp.
           128-5-R1-1]
          Length = 178

 Score =  135 bits (339), Expect = 2e-30,   Method: Composition-based stats.
 Identities = 75/173 (43%), Positives = 111/173 (64%), Gaps = 9/173 (5%)

Query: 12  SVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFG 71
           S+L  E ++  R+R + + I +D+S+          VVV +L+G+FVF AD+VR   +  
Sbjct: 10  SLLIKEDDIRRRVRELGKEIEEDFSD------SEDFVVVGLLKGAFVFVADLVR---EID 60

Query: 72  VPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKK 131
           +P R++FL  SSYG   +S G + +  D   DI G+ VL+++DILDT +TLREV D LK 
Sbjct: 61  LPARIDFLWVSSYGQGMESSGSIRIVKDLDTDIEGRDVLLVDDILDTGITLREVYDFLKI 120

Query: 132 SEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDV 184
             P+ +KT V +DK G RK+ F A+YV  +VPNVF+VGYGLD+ +  R ++ V
Sbjct: 121 KNPSRLKTCVFLDKKGRRKVEFEADYVGFEVPNVFLVGYGLDWGELGRNLKGV 173
>ref|YP_001513548.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus oremlandii
           OhILAs]
 gb|ABW19552.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus oremlandii
           OhILAs]
          Length = 179

 Score =  133 bits (334), Expect = 9e-30,   Method: Composition-based stats.
 Identities = 72/175 (41%), Positives = 110/175 (62%), Gaps = 10/175 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           VL +E ++  R+  + + I+D+Y        +  L V+S+LRGSFVFTAD+VR L    +
Sbjct: 10  VLCSEEDIAARLTALGKEISDEYR-------DKKLYVISLLRGSFVFTADLVRKLD---I 59

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
           P +++F+  SSYGHDT+S G V +  D   ++   HVLV++DI D+ LT++ V+D LK  
Sbjct: 60  PVKIDFMTTSSYGHDTESSGTVQIVTDIKENLEDYHVLVVDDITDSGLTMKFVMDHLKTK 119

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
            P S+K+ V +DKP  RK+    +YV   +P+ FVVGYGL+Y   YR +  V ++
Sbjct: 120 NPQSVKSCVLLDKPERRKVEIVPDYVGFTIPDKFVVGYGLNYGDYYRNIPYVFVV 174
>ref|YP_001213102.1| hypoxanthine-guanine phosphoribosyltransferase [Pelotomaculum
           thermopropionicum SI]
 dbj|BAF60733.1| hypoxanthine-guanine phosphoribosyltransferase [Pelotomaculum
           thermopropionicum SI]
          Length = 181

 Score =  133 bits (334), Expect = 9e-30,   Method: Composition-based stats.
 Identities = 73/180 (40%), Positives = 107/180 (59%), Gaps = 10/180 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           +LFTE E+  R+  + + I+ DY+          L+VV +L+G+ +F AD+VR      V
Sbjct: 8   ILFTEEEIRARVAEMGREISRDYAG-------RELLVVGILKGAMIFLADLVR---SITV 57

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
           P   +F+  SSYG  TKS G V +  D    I G+HVL++EDI+DT LTL  +VD+L   
Sbjct: 58  PAFFDFIAVSSYGTSTKSSGAVRILKDLDRGIEGRHVLIVEDIVDTGLTLNYLVDNLTAR 117

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
            PAS+K    +DKP  R+ P    Y    +P+ FVVGYGLDY++ YR +  +++L P V+
Sbjct: 118 GPASLKVCTLLDKPSRRQKPVEIHYNGFTIPDEFVVGYGLDYNECYRNLPYIMVLSPRVF 177
>ref|YP_001113711.1| hypoxanthine phosphoribosyltransferase [Desulfotomaculum reducens
           MI-1]
 gb|ABO50886.1| hypoxanthine phosphoribosyltransferase [Desulfotomaculum reducens
           MI-1]
          Length = 179

 Score =  132 bits (332), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 67/182 (36%), Positives = 112/182 (61%), Gaps = 10/182 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           +L  E +++ R++ + Q+I  DY           +++V +L+G+ +F AD+VR   +  V
Sbjct: 8   ILLEENQINERIQQLGQQITQDYQG-------KDILMVGILKGAMIFLADLVR---NIEV 57

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
           PT  +F+  SSYG  T S G V +  D    I GKH++++EDI+DT LTL+ +V+++K  
Sbjct: 58  PTFFDFMAVSSYGAGTVSSGVVRILKDLDKSIEGKHIIIVEDIVDTGLTLQYMVENIKSR 117

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
            PAS+K    +DKP  RK+    +Y    +P+ FVVG+GLDY++ YR +  + +LKP +Y
Sbjct: 118 GPASVKVCTLLDKPDRRKVEVPIDYNGFQIPDEFVVGFGLDYNERYRNLPYIAVLKPEIY 177

Query: 193 ET 194
           ++
Sbjct: 178 QS 179
>ref|YP_912357.1| hypoxanthine phosphoribosyltransferase [Chlorobium phaeobacteroides
           DSM 266]
 gb|ABL65933.1| hypoxanthine phosphoribosyltransferase [Chlorobium phaeobacteroides
           DSM 266]
          Length = 177

 Score =  132 bits (331), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 70/176 (39%), Positives = 108/176 (61%), Gaps = 10/176 (5%)

Query: 15  FTEAE-LHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGVP 73
           F  AE LH R+  +   I+ DY+      +  PLV++ VL+G+FV  AD+VR +    +P
Sbjct: 11  FISAERLHNRICELGCDISRDYAG-----IPTPLVIIGVLKGAFVVFADLVRAIT---IP 62

Query: 74  TRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKSE 133
             ++FL ASSYG  T S G V ++   L  I+ +HVL++EDI+D+ LT++ + D L++  
Sbjct: 63  CTIDFLHASSYGSKTVSSGTVTIRHK-LSSIQNRHVLLVEDIIDSGLTMQRITDDLQQMH 121

Query: 134 PASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKP 189
           PAS+K    +DKP  RK P    Y    VP+ F+VGYG+D+++ YRE+  + I+ P
Sbjct: 122 PASMKIFTLLDKPESRKHPVAIAYTGFVVPDKFIVGYGIDFNEQYRELPAIGIINP 177
>ref|YP_460761.1| hypoxanthine-guanine phosphoribosyltransferase [Syntrophus
           aciditrophicus SB]
 gb|ABC76593.1| hypoxanthine-guanine phosphoribosyltransferase [Syntrophus
           aciditrophicus SB]
          Length = 173

 Score =  132 bits (331), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 69/177 (38%), Positives = 111/177 (62%), Gaps = 10/177 (5%)

Query: 12  SVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFG 71
           S+      +  R++ + ++I+ DY+       E+ L++V VL+G+F+F AD++R L    
Sbjct: 7   SIFIPRETIEKRVKELGEQISRDYA-------ESELIIVGVLKGAFIFMADLIRALS--- 56

Query: 72  VPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKK 131
           +P RV+F R +SYG    S G+V +  D    IRG+ +L++EDI+DT LTL+ +VD  ++
Sbjct: 57  IPCRVDFARLASYGSGAASSGKVIMTKDIETSIRGRDILIVEDIVDTGLTLKFLVDWFRE 116

Query: 132 SEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
             P S+K    +DK G RK+PF A+YV   V + FV+GYGLD+D+  R + DV I++
Sbjct: 117 RNPRSLKVCAFLDKQGRRKVPFEADYVGFSVDDAFVIGYGLDFDEKGRFLPDVYIVE 173
>ref|ZP_00530669.1| Hypoxanthine phosphoribosyl transferase [Chlorobium
           phaeobacteroides BS1]
 gb|EAM64912.1| Hypoxanthine phosphoribosyl transferase [Chlorobium
           phaeobacteroides BS1]
          Length = 172

 Score =  131 bits (330), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 68/168 (40%), Positives = 103/168 (61%), Gaps = 11/168 (6%)

Query: 14  LFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGVP 73
           L +  ++  R+  + ++I  D +  +       L+VV VL+G+F+FTAD+VR      +P
Sbjct: 9   LLSAEKIQQRVSEIGRQITADLAGTD------QLLVVGVLKGAFMFTADLVR---SIQIP 59

Query: 74  TRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKSE 133
             +EF+RASSYGH  +S G V +  D   DI    VL++EDI+DT LT+  +V++ +K  
Sbjct: 60  CHIEFIRASSYGHSMQSSGNVAISGD--LDIENHDVLLVEDIIDTGLTILRIVENFRKKN 117

Query: 134 PASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREV 181
           PAS++    +DKP  RK P T +Y    VP+ FVVGYG+DY + YRE+
Sbjct: 118 PASLRICTLLDKPSTRKYPVTVDYSGFSVPDRFVVGYGIDYAEQYREL 165
>ref|YP_001319457.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus
           metalliredigens QYMF]
 gb|ABR47798.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus
           metalliredigens QYMF]
          Length = 179

 Score =  131 bits (330), Expect = 2e-29,   Method: Composition-based stats.
 Identities = 70/175 (40%), Positives = 109/175 (62%), Gaps = 10/175 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           VL +E ++  R++ + ++++ +Y           L V+S+L+GSFVFTAD+VR L    +
Sbjct: 10  VLCSEEDIENRLKELGEQLSIEYKG-------KKLYVISLLKGSFVFTADLVRQLT---I 59

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
           P ++ F+  SSYGHD KS G V +  D   D+ G  VLV +DI D+ LT++EV+D LK  
Sbjct: 60  PVKINFMTTSSYGHDEKSSGHVKIVTDVQEDLTGYDVLVADDITDSGLTMKEVMDHLKSK 119

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
            P+S+K+ V +DKP  RK+    +YV   +P+ FVVGYGL++   YR +  V ++
Sbjct: 120 NPSSVKSCVLLDKPDRRKVDLEPDYVGFTIPDKFVVGYGLNFGDYYRNIPYVFVV 174
>emb|CAO80713.1| Hypoxanthine-guanine phosphoribosyltransferase [Candidatus
           Cloacamonas acidaminovorans]
          Length = 182

 Score =  131 bits (330), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 72/183 (39%), Positives = 111/183 (60%), Gaps = 10/183 (5%)

Query: 11  TSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDF 70
           ++VLF E ++ TR+R +   I++ Y N        P V++ +L+G F+F AD+VR     
Sbjct: 9   SAVLFDEYQIQTRIRELGLEISNSYKN------STP-VMIGILKGGFIFLADLVR---SI 58

Query: 71  GVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLK 130
            +P  V+FL  SSYG  T S G V ++ D   DI G+ V+V+EDI+DT L+L  + D + 
Sbjct: 59  TIPVEVDFLAISSYGTKTSSSGVVKIRKDIDIDITGRDVIVVEDIVDTGLSLAYIKDYIW 118

Query: 131 KSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPS 190
           + +P+S+KT V +DKP   K   T +Y+   + N FVVGYGLD+ + YR +  + ILK  
Sbjct: 119 QHKPSSLKTCVLLDKPDAHKTDVTFDYIGYSIKNEFVVGYGLDFAEKYRNLPFIGILKEE 178

Query: 191 VYE 193
           +Y+
Sbjct: 179 LYK 181
>ref|YP_001161115.1| hypoxanthine phosphoribosyltransferase [Salinispora tropica
           CNB-440]
 gb|ABP56737.1| hypoxanthine phosphoribosyltransferase [Salinispora tropica
           CNB-440]
          Length = 190

 Score =  130 bits (328), Expect = 4e-29,   Method: Composition-based stats.
 Identities = 71/180 (39%), Positives = 112/180 (62%), Gaps = 5/180 (2%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           V+ +EA++  +   +A++++ DY++     +E+ L++V VL+G+ +F AD  R LG  G 
Sbjct: 14  VIISEAQIREKTAELAKQVSADYAD-----VEDGLLLVCVLKGAVMFMADFARALGRQGP 68

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
           P  +EF+  SSYG  T S G V +  D   DI G+HV+V+EDI+D+ LTL  ++  L+  
Sbjct: 69  PAELEFMAISSYGQGTTSSGVVRILKDLDRDIAGRHVVVVEDIVDSGLTLSWLLRYLESR 128

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
             AS++ +    KP   K+P   +YV  D+P  FVVGYGLD+ + YRE+  V +L+P VY
Sbjct: 129 SAASVEVVALFRKPEAVKVPVAVKYVGFDIPTEFVVGYGLDFGERYRELPFVGVLRPEVY 188
>ref|YP_001539489.1| hypoxanthine phosphoribosyltransferase [Salinispora arenicola
           CNS-205]
 gb|ABW00499.1| hypoxanthine phosphoribosyltransferase [Salinispora arenicola
           CNS-205]
          Length = 190

 Score =  130 bits (328), Expect = 5e-29,   Method: Composition-based stats.
 Identities = 71/180 (39%), Positives = 112/180 (62%), Gaps = 5/180 (2%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           V+ +EA++  +   +A++++ DY++     +E+ L++V VL+G+ +F AD  R LG  G 
Sbjct: 14  VIISEAQIREKTAELAKQVSADYAD-----VEDGLLLVCVLKGAVMFMADFARALGRQGP 68

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
           P  +EF+  SSYG  T S G V +  D   DI G+HV+V+EDI+D+ LTL  ++  L+  
Sbjct: 69  PAELEFMAISSYGQGTTSSGVVRILKDLDRDIAGRHVVVVEDIVDSGLTLSWLLRYLESR 128

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
             AS++ +    KP   K+P   +YV  D+P  FVVGYGLD+ + YRE+  V +L+P VY
Sbjct: 129 SAASVEVVALFRKPEAVKVPVEVKYVGFDIPTEFVVGYGLDFGERYRELPYVGVLRPEVY 188
>ref|YP_001512894.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus oremlandii
           OhILAs]
 gb|ABW18898.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus oremlandii
           OhILAs]
          Length = 180

 Score =  130 bits (326), Expect = 8e-29,   Method: Composition-based stats.
 Identities = 69/186 (37%), Positives = 113/186 (60%), Gaps = 9/186 (4%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           Y+    VLF++ ++  +++ + + I+ DY         + LV++ VL+G+ VF AD++R 
Sbjct: 2   YNDVEEVLFSKEDIAKKVKELGEIISKDYKE------NDDLVIIGVLKGANVFMADLMR- 54

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
             +  +P  ++F+  SSYG+ T+S G V +  D   +I GKHVL++EDI+DT LTL+ + 
Sbjct: 55  --EITIPVYIDFMAVSSYGYSTESSGIVRILKDLDLEIEGKHVLIIEDIIDTGLTLKYLT 112

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D+LK     S+K    +DKP  RK     +Y+  ++P+ F+VGYG+DY + YR +  V  
Sbjct: 113 DNLKSRNTKSVKICTLLDKPVRRKCDLKVDYMGFEIPDKFIVGYGIDYGERYRNLPYVAS 172

Query: 187 LKPSVY 192
           LKP VY
Sbjct: 173 LKPEVY 178
>ref|YP_074329.1| hypoxanthine-guanine phosphoribosyltransferase [Symbiobacterium
           thermophilum IAM 14863]
 dbj|BAD39485.1| hypoxanthine-guanine phosphoribosyltransferase [Symbiobacterium
           thermophilum IAM 14863]
          Length = 179

 Score =  129 bits (324), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 69/182 (37%), Positives = 112/182 (61%), Gaps = 10/182 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           VL TE ++  +++ +  +I++D+           LVVV +L+G+ +F AD+ R +    +
Sbjct: 8   VLITEEQIREKIKELGAQISEDFRG-------KDLVVVGILKGAALFCADLFRAIS---I 57

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
           P  ++F+R +SYG  TKS G   V  D    + G+HVL++EDI+DT LT++ + + L + 
Sbjct: 58  PAELDFMRITSYGAATKSTGVHRVLLDLDYTLEGRHVLIVEDIVDTGLTIKFLKEYLSQR 117

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
            PAS+     +DKP  RK+  T +Y   +VP+ FVVG GLDY + YR +RD+ ILKP +Y
Sbjct: 118 GPASLSVAALLDKPSRRKVEVTIDYRGFEVPDFFVVGMGLDYAEKYRNLRDICILKPEIY 177

Query: 193 ET 194
           ++
Sbjct: 178 KS 179
>ref|ZP_01666882.1| hypoxanthine phosphoribosyltransferase [Thermosinus carboxydivorans
           Nor1]
 gb|EAX47240.1| hypoxanthine phosphoribosyltransferase [Thermosinus carboxydivorans
           Nor1]
          Length = 179

 Score =  129 bits (323), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 68/182 (37%), Positives = 111/182 (60%), Gaps = 10/182 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           +L +  +L  R+R + ++I+ DY+          ++++ VLRG+ +F AD+ R +    V
Sbjct: 8   ILLSSEQLSARIREMGRQISADYAG-------KEILMIGVLRGAVIFMADLARAID---V 57

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
           P  ++F+  SSYG  T S G V +  D   D+ GKH+L++EDI+D+ LTL  ++D+L+  
Sbjct: 58  PVALDFMAVSSYGASTTSSGVVRILKDLDEDVEGKHLLIVEDIIDSGLTLNYLLDNLRSR 117

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
           +PASIK    ++KP  RK+    +Y    +P+ FVVGYGLDY + YR +  + ILKP  Y
Sbjct: 118 KPASIKICTLLNKPERRKVDVQVDYNGFTIPDHFVVGYGLDYAEKYRNLPFIGILKPEAY 177

Query: 193 ET 194
           ++
Sbjct: 178 KS 179
>ref|YP_001916267.1| hypoxanthine phosphoribosyltransferase [Natranaerobius thermophilus
           JW/NM-WN-LF]
 gb|ACB83679.1| hypoxanthine phosphoribosyltransferase [Natranaerobius thermophilus
           JW/NM-WN-LF]
          Length = 181

 Score =  129 bits (323), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 72/187 (38%), Positives = 112/187 (59%), Gaps = 11/187 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           ME A   D A   L +E E+  +++ + ++I+ DY           ++ V VL+GSFVF 
Sbjct: 1   MERAYDKD-AFKQLISEEEIKDKVKELGEQISQDYQG-------QEVIAVGVLKGSFVFA 52

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD++R L    +P  ++FL  SSYG  TKS G + +  D    I  KHVL++EDI+DT L
Sbjct: 53  ADLLRQLS---IPNEIDFLAVSSYGASTKSSGIIRILKDLDTSIENKHVLIVEDIVDTGL 109

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  ++++L   +PAS+K    +DKP  R++  T +Y+   +P++FVVGYGLDY + YR+
Sbjct: 110 TLNYLLETLSTRKPASLKICTLLDKPDRREVDLTPDYIGFQIPDLFVVGYGLDYAEYYRD 169

Query: 181 VRDVVIL 187
              + +L
Sbjct: 170 WPAIYVL 176
>ref|NP_782785.1| hypoxanthine-guanine phosphoribosyltransferase [Clostridium tetani
           E88]
 gb|AAO36722.1| hypoxanthine-guanine phosphoribosyltransferase [Clostridium tetani
           E88]
          Length = 178

 Score =  129 bits (323), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 70/172 (40%), Positives = 106/172 (61%), Gaps = 10/172 (5%)

Query: 10  ATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGD 69
           A ++L T+ E+  ++  + ++I+ DY   NL        V+S+LRGSF+FT+D+VR +  
Sbjct: 9   ARNILITKEEIQQKVEAMGKKISKDYEGKNL-------YVLSLLRGSFMFTSDLVRYIT- 60

Query: 70  FGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSL 129
             VPTR+ F+  SSYGH   S G+V V  D   DI+G  VL+++DI+DT +T+  V + +
Sbjct: 61  --VPTRIGFMTTSSYGHGEVSTGKVKVVNDIPDDIKGMDVLIVDDIVDTGITMDFVKNHV 118

Query: 130 KKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREV 181
           K     S+K+ V +DKP  RK+    EY    +P+VFVVGYGL+Y   YR +
Sbjct: 119 KSLGANSVKSCVLLDKPERRKLDLVPEYCCFSIPDVFVVGYGLNYGDFYRNI 170
>ref|NP_784322.1| hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus
           plantarum WCFS1]
 emb|CAD63163.1| hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus
           plantarum WCFS1]
          Length = 180

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 69/181 (38%), Positives = 113/181 (62%), Gaps = 10/181 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           VL++  ++H   + + + +   Y+       +NPL++  VL+G+ +FT D++R   +  +
Sbjct: 8   VLYSREDIHQVAQKLGKELTTAYAG------KNPLIIC-VLKGAVLFTTDIIR---EMDI 57

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
              ++F+  SSYG++T S G V +  D   D+ G+ VLV+EDI+DT  TL+ ++D LK+ 
Sbjct: 58  YADLDFINLSSYGNETISSGEVQLTKDLDADVTGRDVLVIEDIIDTGRTLKFLIDLLKRR 117

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
           +  S+K    +DKP GR +   A+Y+  +VPN FVVGYGLDY + YR +  V ILKP++Y
Sbjct: 118 DVNSVKVCTLLDKPAGRLVDIKADYIGFEVPNEFVVGYGLDYAERYRNLPYVGILKPAIY 177

Query: 193 E 193
           E
Sbjct: 178 E 178
>ref|ZP_02037643.1| hypothetical protein BACCAP_03261 [Bacteroides capillosus ATCC
           29799]
 gb|EDM98927.1| hypothetical protein BACCAP_03261 [Bacteroides capillosus ATCC
           29799]
          Length = 182

 Score =  128 bits (322), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 76/180 (42%), Positives = 107/180 (59%), Gaps = 10/180 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           VLF+E EL  R+  +A  I  DY+       + P+++ SVLRGSFVF AD+ R      V
Sbjct: 9   VLFSEEELDKRVSEIAAEINRDYAG------KEPMLI-SVLRGSFVFMADLTR---KIEV 58

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
           P  ++F+  SSYG  T S G+V +  D   DI GK ++V+EDILD+  TL  +++ L+  
Sbjct: 59  PCTIDFMSVSSYGKGTTSSGQVQITKDLSDDIEGKDIIVVEDILDSGNTLSYLLELLRAR 118

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
           +PAS+K    +DKP  R      +Y    +P+ FVVGYGLDY + YR +  + ILKP VY
Sbjct: 119 KPASMKLCTLLDKPDRRVKEVHVDYSGFTIPDEFVVGYGLDYAEKYRNLPYIGILKPRVY 178
>ref|YP_002769603.1| hypoxanthine-guanine phosphoribosyltransferase [Brevibacillus
           brevis NBRC 100599]
 dbj|BAH41099.1| hypoxanthine-guanine phosphoribosyltransferase [Brevibacillus
           brevis NBRC 100599]
          Length = 179

 Score =  127 bits (320), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 68/180 (37%), Positives = 112/180 (62%), Gaps = 10/180 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           +L +E ++  ++R + + +A +Y +      +NPLV+  VL+G+ +F AD++R      +
Sbjct: 8   ILLSEEDIAGKVRELGETLAAEYKD------KNPLVIC-VLKGAVIFMADLIR---HMSI 57

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
           P  ++F+  SSYG  T+S G V +  D    +  +HVLV+EDI+D+ LTL  +V+ L+  
Sbjct: 58  PCEMDFMAVSSYGSGTESSGMVKILKDLDTSVENRHVLVVEDIMDSGLTLSRLVELLRHR 117

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
           E AS+K +  ++KP  RK+  + +Y   DVP+ FVVGYGLDY + YR +  + +LKP VY
Sbjct: 118 EAASVKVVTLLNKPERRKVDISPDYKGYDVPDEFVVGYGLDYAEHYRNLPYIGVLKPEVY 177
>ref|ZP_02091227.1| hypothetical protein FAEPRAM212_01498 [Faecalibacterium prausnitzii
           M21/2]
 gb|EDP21677.1| hypothetical protein FAEPRAM212_01498 [Faecalibacterium prausnitzii
           M21/2]
          Length = 180

 Score =  127 bits (320), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 76/187 (40%), Positives = 111/187 (59%), Gaps = 11/187 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           +D   +VL +E +L  ++  +  +I+ DY+  NL       V+VS+L+GS VF AD++R 
Sbjct: 2   HDDIKTVLVSEEQLKAKVAELGAQISRDYAGKNL-------VLVSILKGSVVFMADLMRA 54

Query: 67  LGDFGVPTRVEFLRASSYG-HDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
           +    +P  ++F+  SSYG  +T + G V +  D   D+ GK VL++EDILDT +TL  +
Sbjct: 55  VS---IPCNIDFMVVSSYGGSNTTTSGLVKIIKDLDGDLSGKDVLIVEDILDTGVTLSNL 111

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
           V  LK   P S+K    +DKP  RK     +Y    VP+ FVVGYGLDYD+ YR +  V 
Sbjct: 112 VPMLKMRNPNSVKICTILDKPSRRKADIQPDYEGFQVPDEFVVGYGLDYDEKYRNLPYVG 171

Query: 186 ILKPSVY 192
           +LKP VY
Sbjct: 172 VLKPEVY 178
>ref|ZP_02951334.1| hypoxanthine phosphoribosyltransferase [Clostridium butyricum 5521]
 gb|EDT73724.1| hypoxanthine phosphoribosyltransferase [Clostridium butyricum 5521]
          Length = 179

 Score =  127 bits (318), Expect = 7e-28,   Method: Composition-based stats.
 Identities = 69/181 (38%), Positives = 112/181 (61%), Gaps = 10/181 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           VLF+E  L  ++R +A +I+ DY           LVVV +L+GS VFTA++++   +  +
Sbjct: 8   VLFSEEVLSEKVRELAVQISKDYKG-------KELVVVGILKGSVVFTAELIK---NIDI 57

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
              ++F+  SSYG+ T++ G V +  D    I GKH+L++EDI+DT  TL  ++  LK  
Sbjct: 58  YCELDFMAVSSYGNSTETTGVVRILKDLDNSIEGKHILIVEDIVDTGTTLSYLLKYLKAR 117

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
           + ASI+ +  ++KP  RK+    +Y+  +VP+ F+VGYG+DY + YR +  + ILKP +Y
Sbjct: 118 KAASIEIVALLNKPARRKVELPVKYIGFEVPDAFIVGYGIDYAEKYRNLPCIGILKPEIY 177

Query: 193 E 193
           E
Sbjct: 178 E 178
>ref|ZP_03958961.1| hypoxanthine phosphoribosyltransferase [Lactobacillus vaginalis
           ATCC 49540]
 gb|EEJ41477.1| hypoxanthine phosphoribosyltransferase [Lactobacillus vaginalis
           ATCC 49540]
          Length = 180

 Score =  127 bits (318), Expect = 7e-28,   Method: Composition-based stats.
 Identities = 70/181 (38%), Positives = 115/181 (63%), Gaps = 10/181 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           VL+++ +++ RM  +A ++  +Y +      + PL+V SV+ G+ +FT DM++ +    +
Sbjct: 8   VLYSKDDINRRMDELANQLTAEYKD------QRPLIV-SVMTGAVLFTVDMIKRMD---I 57

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
             +++F+  SSY   T S G+V +  D   D+RG+ +L++EDI+DT  TL+ ++D LK+ 
Sbjct: 58  MAKLDFIDVSSYYGGTSSTGKVKLVQDLKSDVRGRSILIMEDIVDTGHTLKYLIDLLKER 117

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
              S+K    +DKP GR++   A+YV  +VPN F+VGYGLDY   YR +  V ILKP+VY
Sbjct: 118 GAKSVKVCTLLDKPEGRQVEVKADYVGFNVPNEFLVGYGLDYQGYYRNLPYVGILKPAVY 177

Query: 193 E 193
           E
Sbjct: 178 E 178
>ref|YP_001678694.1| hypoxanthine phosphoribosyltransferase [Heliobacterium
           modesticaldum Ice1]
 gb|ABZ82683.1| hypoxanthine phosphoribosyltransferase [Heliobacterium
           modesticaldum Ice1]
          Length = 179

 Score =  126 bits (317), Expect = 9e-28,   Method: Composition-based stats.
 Identities = 70/181 (38%), Positives = 108/181 (59%), Gaps = 10/181 (5%)

Query: 13  VLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGDFGV 72
           VL +E ++  +++ + +RI+ DY        +  L+VV +L+G+ VF AD++R +    +
Sbjct: 8   VLVSEEDIRVKVKELGERISKDYQ-------DKDLLVVGILKGALVFMADLIRAIH---I 57

Query: 73  PTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSLKKS 132
           P  ++F+  SSYG   KS G V +  D    I  +H+L++EDI+DT LTL  ++D+LK  
Sbjct: 58  PIEIDFMAVSSYGAGAKSSGAVRILKDLDRAIENRHILIVEDIVDTGLTLNYLMDNLKSR 117

Query: 133 EPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKPSVY 192
             AS+K   A+DKP  RK   T +Y    +P+ FV+GYGLDY + YR    V +LK  VY
Sbjct: 118 GAASVKVCTALDKPSRRKTLVTPDYNGFTIPDEFVIGYGLDYAEQYRHFPFVAVLKREVY 177

Query: 193 E 193
           E
Sbjct: 178 E 178
Searching..................................................done Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|ZP_01666882.1|  hypoxanthine phosphoribosyltransferase [...   300   5e-80
ref|YP_001113711.1|  hypoxanthine phosphoribosyltransferase ...   297   2e-79
gb|EEJ98066.1|  hypoxanthine phosphoribosyltransferase [Ther...   297   3e-79
ref|NP_469596.1|  fusion protein, N-terminal part similar to...   291   2e-77
ref|YP_359913.1|  hypoxanthine phosphoribosyltransferase [Ca...   291   3e-77
ref|XP_816916.1|  hypoxanthine-guanine phosphoribosyltransfe...   291   3e-77
ref|ZP_02276207.1|  hypothetical protein LmonFS_00952 [Liste...   290   4e-77
ref|ZP_01514399.1|  hypoxanthine phosphoribosyltransferase [...   290   4e-77
ref|YP_012840.1|  conserved hypothetical protein/hypoxanthin...   290   4e-77
ref|ZP_02686823.1|  hypothetical protein LmonFSL_00295 [List...   290   4e-77
ref|ZP_01926199.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   290   4e-77
ref|NP_463750.1|  fusion protein, N-terminal part similar to...   290   4e-77
ref|ZP_00230936.1|  conserved hypothetical protein/hypoxanth...   290   4e-77
ref|NP_627611.1|  hypoxanthine phosphoribosyltransferase [St...   290   4e-77
ref|XP_822405.1|  hypoxanthine-guanine phosphoribosyltransfe...   290   5e-77
ref|NP_825842.1|  hypoxanthine phosphoribosyltransferase [St...   290   5e-77
ref|ZP_01928838.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   290   5e-77
ref|ZP_01942347.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   289   6e-77
pdb|1TC2|A  Chain A, Ternary Substrate Complex Of The Hypoxa...   289   6e-77
ref|XP_822398.1|  hypoxanthine-guanine phosphoribosyltransfe...   289   6e-77
pdb|1TC1|A  Chain A, A 1.4 Angstrom Crystal Structure For Th...   289   7e-77
pdb|1P17|A  Chain A, Hypoxanthine Phosphoribosyltransferase ...   289   1e-76
ref|YP_001213102.1|  hypoxanthine-guanine phosphoribosyltran...   289   1e-76
ref|ZP_03924809.1|  hypoxanthine phosphoribosyltransferase [...   288   2e-76
ref|YP_848383.1|  conserved hypothetical/hypoxanthine phosph...   288   2e-76
ref|ZP_02091227.1|  hypothetical protein FAEPRAM212_01498 [F...   288   2e-76
ref|XP_813396.1|  hypoxanthine-guanine phosphoribosyltransfe...   288   2e-76
ref|ZP_02037643.1|  hypothetical protein BACCAP_03261 [Bacte...   288   2e-76
ref|YP_001274703.1|  hypoxanthine phosphoribosyltransferase ...   287   3e-76
ref|YP_002769603.1|  hypoxanthine-guanine phosphoribosyltran...   287   3e-76
ref|YP_001430999.1|  hypoxanthine phosphoribosyltransferase ...   287   4e-76
ref|YP_001825599.1|  putative hypoxanthine phosphoribosyltra...   287   4e-76
ref|YP_644942.1|  hypoxanthine phosphoribosyltransferase [Ru...   287   4e-76
ref|ZP_02330217.1|  hypothetical protein Plarl_21636 [Paenib...   285   1e-75
ref|NP_814058.1|  hypoxanthine-guanine phosphoribosyltransfe...   285   1e-75
pdb|1I14|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   285   1e-75
pdb|1I0L|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   285   1e-75
pdb|1I0I|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   284   2e-75
ref|YP_290952.1|  hypoxanthine phosphoribosyl transferase [T...   284   3e-75
pdb|1I13|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   284   4e-75
ref|ZP_02581448.1|  hypoxanthine phosphoribosyltransferase [...   283   4e-75
ref|ZP_03922784.1|  hypoxanthine phosphoribosyltransferase [...   283   5e-75
ref|ZP_00741717.1|  Hypoxanthine-guanine phosphoribosyltrans...   283   6e-75
ref|ZP_00603444.1|  Hypoxanthine phosphoribosyl transferase ...   283   6e-75
ref|YP_001642956.1|  hypoxanthine phosphoribosyltransferase ...   283   6e-75
ref|YP_001512894.1|  hypoxanthine phosphoribosyltransferase ...   283   6e-75
ref|YP_001695855.1|  Hypoxanthine-guanine phosphoribosyltran...   283   7e-75
ref|YP_001626350.1|  hypoxanthine-guanine phosphoribosyltran...   282   9e-75
ref|ZP_03982713.1|  Hypoxanthine phosphoribosyltransferase [...   282   9e-75
ref|NP_240950.1|  hypoxanthine-guanine phosphoribosyltransfe...   282   1e-74
ref|YP_001256007.1|  hypoxanthine phosphoribosyltransferase ...   282   1e-74
ref|ZP_02618270.1|  hypoxanthine phosphoribosyltransferase [...   282   2e-74
ref|ZP_02525183.1|  hypoxanthine phosphoribosyltransferase [...   281   2e-74
ref|NP_842632.1|  hypoxanthine-guanine phosphoribosyltransfe...   281   2e-74
ref|YP_001373429.1|  hypoxanthine phosphoribosyltransferase ...   281   2e-74
ref|YP_001539489.1|  hypoxanthine phosphoribosyltransferase ...   281   2e-74
ref|ZP_02836636.1|  hypoxanthine phosphoribosyltransferase [...   281   2e-74
ref|ZP_01725398.1|  hypoxanthine-guanine phosphoribosyltrans...   281   2e-74
ref|ZP_04009409.1|  hypoxanthine-guanine phosphoribosyltrans...   281   2e-74
ref|YP_001320712.1|  hypoxanthine phosphoribosyltransferase ...   281   2e-74
ref|ZP_02993965.1|  hypothetical protein CLOSPO_01067 [Clost...   281   3e-74
ref|ZP_03927309.1|  hypoxanthine phosphoribosyltransferase [...   281   3e-74
ref|YP_945962.1|  hypoxanthine phosphoribosyltransferase [Ar...   281   3e-74
ref|YP_536242.1|  Hypoxanthine-guanine phosphoribosyltransfe...   281   3e-74
ref|ZP_02263469.1|  hypoxanthine phosphoribosyltransferase [...   280   4e-74
ref|ZP_03856335.1|  hypoxanthine phosphoribosyltransferase [...   280   5e-74
ref|YP_829651.1|  hypoxanthine phosphoribosyltransferase [Ar...   280   5e-74
ref|YP_520172.1|  hypothetical protein DSY3939 [Desulfitobac...   280   5e-74
ref|YP_001161115.1|  hypoxanthine phosphoribosyltransferase ...   280   5e-74
ref|YP_001485312.1|  hypoxanthine phosphoribosyltransferase ...   280   5e-74
ref|YP_001360283.1|  hypoxanthine phosphoribosyltransferase ...   279   1e-73
ref|ZP_02044194.1|  hypothetical protein ACTODO_01053 [Actin...   279   1e-73
ref|NP_829966.1|  hypoxanthine-guanine phosphoribosyltransfe...   279   1e-73
ref|ZP_00994139.1|  putative hypoxanthine phosphoribosyltran...   279   1e-73
ref|ZP_02185480.1|  hypoxanthine-guanine phosphoribosyltrans...   278   2e-73
ref|ZP_01950602.1|  hypoxanthine phosphoribosyltransferase [...   278   2e-73
ref|ZP_02849796.1|  hypoxanthine phosphoribosyltransferase [...   278   2e-73
ref|YP_173609.1|  hypoxanthine-guanine phosphoribosyltransfe...   278   2e-73
ref|YP_062949.1|  hypoxanthine phosphoribosyltransferase [Le...   277   2e-73
ref|ZP_00379834.1|  COG0634: Hypoxanthine-guanine phosphorib...   277   3e-73
ref|ZP_00832718.1|  COG0634: Hypoxanthine-guanine phosphorib...   277   3e-73
ref|ZP_02281563.1|  hypothetical protein LmonL_01842 [Lister...   277   3e-73
ref|YP_001678694.1|  hypoxanthine phosphoribosyltransferase ...   277   3e-73
ref|YP_001855782.1|  hypoxanthine phosphoribosyltransferase ...   277   3e-73
ref|NP_406870.1|  hypoxanthine-guanine phosphoribosyltransfe...   277   3e-73
ref|YP_652817.1|  hypoxanthine phosphoribosyltransferase [Ye...   277   3e-73
ref|NP_668114.2|  hypoxanthine-guanine phosphoribosyltransfe...   277   3e-73
ref|ZP_03910773.1|  hypoxanthine phosphoribosyltransferase [...   277   4e-73
ref|ZP_02278787.1|  hypothetical protein LmonF_02357 [Lister...   277   4e-73
ref|YP_646612.1|  hypoxanthine phosphoribosyltransferase [Ye...   277   4e-73
gb|AAB41678.1|  hypoxanthine-guanine phosphoribosyltransferase    277   4e-73
ref|YP_921672.1|  hypoxanthine phosphoribosyltransferase [No...   277   4e-73
ref|ZP_02951334.1|  hypoxanthine phosphoribosyltransferase [...   277   5e-73
ref|NP_230235.1|  hypoxanthine-guanine phosphoribosyltransfe...   276   5e-73
ref|ZP_03868259.1|  hypoxanthine phosphoribosyltransferase [...   276   5e-73
ref|ZP_03826612.1|  hypoxanthine-guanine phosphoribosyltrans...   276   6e-73
emb|CAG21486.1|  putative hypoxanthine ribosyl transferase [...   276   7e-73
ref|ZP_03833725.1|  hypoxanthine-guanine phosphoribosyltrans...   276   7e-73
ref|ZP_01236067.1|  hypoxanthine-guanine phosphoribosyltrans...   276   8e-73
ref|YP_069264.1|  hypoxanthine-guanine phosphoribosyltransfe...   276   8e-73
ref|ZP_02943585.1|  hypoxanthine phosphoribosyltransferase [...   276   9e-73
ref|YP_001402308.1|  hypoxanthine phosphoribosyltransferase ...   276   9e-73
emb|CAG76226.1|  hypoxanthine phosphoribosyltransferase [Erw...   276   9e-73
dbj|BAF43658.1|  hypoxanthine ribosyl transferase [Photobact...   276   1e-72
ref|YP_001333823.1|  hypoxanthine-guanine phosphoribosyltran...   276   1e-72
ref|ZP_00826602.1|  COG0634: Hypoxanthine-guanine phosphorib...   276   1e-72
ref|YP_051417.2|  hypoxanthine-guanine phosphoribosyltransfe...   275   1e-72
ref|YP_001916267.1|  hypoxanthine phosphoribosyltransferase ...   275   1e-72
ref|ZP_03994351.1|  hypoxanthine phosphoribosyltransferase [...   275   1e-72
ref|ZP_01129459.1|  hypoxanthine phosphoribosyltransferase [...   275   1e-72
ref|YP_001906795.1|  Hypoxanthine phosphoribosyltransferase ...   275   1e-72
ref|ZP_01481302.1|  hypothetical protein VchoR_02002821 [Vib...   275   2e-72
ref|ZP_01160633.1|  hypoxanthine-guanine phosphoribosyltrans...   275   2e-72
ref|ZP_03813362.1|  hypoxanthine phosphoribosyltransferase [...   275   2e-72
ref|YP_001480221.1|  hypoxanthine phosphoribosyltransferase ...   275   2e-72
ref|ZP_01992529.1|  hypoxanthine phosphoribosyltransferase [...   274   2e-72
ref|ZP_02643856.1|  hypoxanthine phosphoribosyltransferase [...   274   2e-72
ref|YP_877129.1|  hypoxanthine phosphoribosyltransferase [Cl...   274   2e-72
ref|YP_697159.1|  hypoxanthine phosphoribosyltransferase [Cl...   274   2e-72
ref|YP_001557268.1|  hypoxanthine phosphoribosyltransferase ...   274   2e-72
ref|ZP_00821598.1|  COG0634: Hypoxanthine-guanine phosphorib...   274   3e-72
ref|NP_563387.1|  hypoxanthine-guanine phosphoribosyltransfe...   274   3e-72
ref|NP_798894.1|  hypoxanthine-guanine phosphoribosyltransfe...   274   3e-72
ref|ZP_01189486.1|  Hypoxanthine phosphoribosyl transferase ...   274   3e-72
ref|YP_001708886.1|  putative hypoxanthine phosphoribosyltra...   274   3e-72
ref|YP_001221583.1|  hypothetical protein CMM_0843 [Clavibac...   274   3e-72
ref|NP_935562.1|  hypoxanthine-guanine phosphoribosyltransfe...   274   3e-72
ref|YP_001586484.1|  hypothetical protein SPAB_00209 [Salmon...   274   3e-72
ref|ZP_02081126.1|  hypothetical protein CLOLEP_02599 [Clost...   273   5e-72
ref|ZP_03958058.1|  hypoxanthine-guanine phosphoribosyltrans...   273   5e-72
ref|ZP_01815583.1|  hypoxanthine-guanine phosphoribosyltrans...   273   5e-72
ref|ZP_03856512.1|  hypoxanthine phosphoribosyltransferase [...   273   5e-72
ref|YP_131288.2|  hypoxanthine-guanine phosphoribosyltransfe...   273   5e-72
ref|ZP_01262549.1|  hypoxanthine-guanine phosphoribosyltrans...   273   5e-72
gb|AAX64076.1|  hypoxanthine phosphoribosyltransferase [Salm...   273   6e-72
ref|YP_001439265.1|  hypothetical protein ESA_03207 [Enterob...   273   6e-72
ref|ZP_01220020.1|  hypoxanthine-guanine phosphoribosyltrans...   273   7e-72
ref|YP_699727.1|  hypoxanthine phosphoribosyltransferase [Cl...   272   8e-72
ref|YP_001812555.1|  hypoxanthine phosphoribosyltransferase ...   272   8e-72
ref|ZP_01988476.1|  hypoxanthine phosphoribosyltransferase [...   272   8e-72
ref|YP_001635640.1|  hypoxanthine phosphoribosyltransferase ...   272   1e-71
ref|YP_205559.1|  hypoxanthine phosphoribosyltransferase [Vi...   272   1e-71
ref|YP_074329.1|  hypoxanthine-guanine phosphoribosyltransfe...   272   1e-71
ref|YP_396211.1|  Hypoxanthine phosphoribosyltranferase [Lac...   272   1e-71
ref|NP_780915.1|  hypoxanthine-guanine phosphoribosyltransfe...   272   1e-71
ref|ZP_00831594.1|  COG0634: Hypoxanthine-guanine phosphorib...   272   1e-71
ref|YP_149518.1|  hypoxanthine-guanine phosphoribosyltransfe...   272   1e-71
ref|ZP_01066590.1|  hypoxanthine-guanine phosphoribosyltrans...   272   1e-71
dbj|BAF43662.1|  hypoxanthine ribosyl transferase [Vibrio fi...   272   1e-71
ref|ZP_03845145.1|  hypoxanthine-guanine phosphoribosyltrans...   272   1e-71
ref|ZP_02685950.1|  hypothetical protein Salmentericaenteric...   272   2e-71
ref|NP_459175.1|  hypoxanthine-guanine phosphoribosyltransfe...   272   2e-71
ref|YP_687706.1|  hypoxanthine phosphoribosyltransferase [Sh...   272   2e-71
ref|YP_807706.1|  Hypoxanthine-guanine phosphoribosyltransfe...   272   2e-71
ref|NP_690999.1|  hypoxanthine phosphoribosyltransferase [Oc...   271   2e-71
sp|P18134|HPRT_VIBHA  Hypoxanthine phosphoribosyltransferase...   271   2e-71
ref|ZP_02348869.1|  hypothetical protein Sententeri_03139 [S...   271   2e-71
ref|NP_454783.1|  hypoxanthine-guanine phosphoribosyltransfe...   271   2e-71
ref|YP_001571814.1|  hypothetical protein SARI_02824 [Salmon...   271   2e-71
emb|CAE13159.1|  unnamed protein product [Photorhabdus lumin...   271   2e-71
ref|NP_928203.2|  hypoxanthine-guanine phosphoribosyltransfe...   271   3e-71
ref|ZP_02653366.1|  hypothetical protein Sententeric_20357 [...   271   3e-71
ref|ZP_02444150.1|  hypothetical protein ANACOL_03471 [Anaer...   271   3e-71
ref|NP_687051.1|  hypoxanthine-guanine phosphoribosyltransfe...   271   3e-71
ref|YP_001175411.1|  hypoxanthine phosphoribosyltransferase ...   270   4e-71
ref|YP_138556.1|  hypoxanthine-guanine phosphoribosyltransfe...   270   4e-71
ref|ZP_03860374.1|  hypoxanthine phosphoribosyltransferase [...   270   4e-71
ref|ZP_02832830.1|  hypothetical protein Salentericaenterica...   270   5e-71
ref|YP_493197.1|  hypoxanthine phosphoribosyltransferase [St...   270   5e-71
ref|YP_001574409.1|  hypoxanthine phosphoribosyltransferase ...   270   5e-71
ref|YP_002806730.1|  hypoxanthine-guanine phosphoribosyltran...   270   6e-71
ref|ZP_02991800.1|  hypoxanthine phosphoribosyltransferase [...   269   6e-71
ref|YP_539179.1|  hypoxanthine phosphoribosyltransferase [Es...   269   7e-71
ref|ZP_02042278.1|  hypothetical protein RUMGNA_03077 [Rumin...   269   7e-71
ref|ZP_00134029.2|  COG0634: Hypoxanthine-guanine phosphorib...   269   8e-71
ref|ZP_02340312.1|  hypothetical protein Sentent_15771 [Salm...   269   8e-71
ref|ZP_02919438.1|  hypothetical protein STRINF_00277 [Strep...   269   9e-71
ref|NP_371034.1|  hypoxanthine-guanine phosphoribosyltransfe...   269   9e-71
ref|ZP_01995978.1|  hypothetical protein DORLON_01976 [Dorea...   269   9e-71
ref|NP_720499.1|  hypoxanthine-guanine phosphoribosyltransfe...   269   1e-70
ref|ZP_01825459.1|  hypoxanthine phosphoribosyltransferase [...   269   1e-70
ref|ZP_02903074.1|  hypoxanthine phosphoribosyltransferase [...   269   1e-70
ref|YP_001053387.1|  yypoxanthine phosphoribosyltransferase ...   268   1e-70
ref|NP_308156.2|  hypoxanthine-guanine phosphoribosyltransfe...   268   1e-70
ref|YP_001843036.1|  hypoxanthine-guanine phosphoribosyltran...   268   1e-70
ref|YP_309162.2|  hypoxanthine phosphoribosyltransferase [Sh...   268   1e-70
ref|ZP_00718322.1|  COG0634: Hypoxanthine-guanine phosphorib...   268   2e-70
gb|EEH95076.1|  hypoxanthine-guanine phosphoribosyltransfera...   268   2e-70
ref|YP_001726475.1|  hypoxanthine phosphoribosyltransferase ...   268   2e-70
ref|YP_001454762.1|  hypothetical protein CKO_03242 [Citroba...   268   2e-70
gb|AAZ86927.1|  hypoxanthine phosphoribosyltransferase [Shig...   268   2e-70
ref|ZP_03835281.1|  hypothetical protein CATC2_04748 [Citrob...   268   2e-70
ref|NP_928199.1|  hypoxanthine-guanine phosphoribosyltransfe...   268   2e-70
ref|ZP_03894492.1|  hypoxanthine phosphoribosyltransferase [...   268   2e-70
ref|ZP_04002769.1|  hypoxanthine phosphoribosyltransferase [...   268   2e-70
ref|ZP_01896236.1|  hypoxanthine-guanine phosphoribosyltrans...   268   2e-70
ref|YP_054976.1|  putative hypoxanthine phosphoribosyltransf...   268   2e-70
ref|NP_344565.1|  hypoxanthine-guanine phosphoribosyltransfe...   267   2e-70
ref|ZP_00992731.1|  hypoxanthine-guanine phosphoribosyltrans...   267   2e-70
ref|YP_254416.1|  putative hypoxanthine-guanine phosphoribos...   267   4e-70
ref|YP_794711.1|  Hypoxanthine-guanine phosphoribosyltransfe...   267   4e-70
ref|ZP_03986123.1|  hypoxanthine phosphoribosyltransferase [...   267   4e-70
ref|YP_001307245.1|  hypoxanthine phosphoribosyltransferase ...   267   4e-70
ref|YP_001742252.1|  hypoxanthine phosphoribosyltransferase ...   267   5e-70
pdb|1G9S|A  Chain A, Crystal Structure Of A Complex Between ...   267   5e-70
sp|Q27541|HPRT_CRIFA  Hypoxanthine-guanine phosphoribosyltra...   266   7e-70
ref|NP_349799.1|  Hypoxanthine-guanine phosphoribosyltransfe...   266   8e-70
ref|ZP_02478331.1|  hypoxanthine phosphoribosyltransferase [...   266   9e-70
ref|ZP_01869538.1|  hypoxanthine-guanine phosphoribosyltrans...   265   9e-70
ref|YP_001884418.1|  hypoxanthine phosphoribosyltransferase ...   265   9e-70
ref|YP_268483.1|  hypoxanthine-guanine phosphoribosyltransfe...   265   1e-69
ref|YP_048119.1|  hypoxanthine phosphoribosyltransferase [Ac...   265   1e-69
ref|YP_001545794.1|  hypoxanthine phosphoribosyltransferase ...   265   2e-69
ref|ZP_01788849.1|  hypoxanthine-guanine phosphoribosyltrans...   265   2e-69
ref|ZP_01704836.1|  hypoxanthine phosphoribosyltransferase [...   265   2e-69
ref|ZP_02288498.1|  hypothetical protein LmonocyFSL_01672 [L...   265   2e-69
ref|YP_735273.1|  hypoxanthine phosphoribosyltransferase [Sh...   265   2e-69
ref|ZP_03935989.1|  hypoxanthine phosphoribosyltransferase [...   265   2e-69
ref|ZP_02210445.1|  hypothetical protein CLOBAR_02853 [Clost...   264   2e-69
ref|YP_302336.1|  putative hypoxanthine-guanine phosphoribos...   264   2e-69
ref|ZP_01965205.1|  hypothetical protein RUMOBE_02936 [Rumin...   264   2e-69
ref|YP_001919611.1|  hypoxanthine phosphoribosyltransferase ...   264   2e-69
ref|NP_439311.1|  hypoxanthine-guanine phosphoribosyltransfe...   264   2e-69
ref|YP_001715593.1|  hypoxanthine phosphoribosyltransferase ...   264   3e-69
ref|ZP_00155585.2|  COG0634: Hypoxanthine-guanine phosphorib...   264   4e-69
ref|ZP_01783677.1|  hypoxanthine-guanine phosphoribosyltrans...   264   4e-69
ref|ZP_01841716.1|  hypoxanthine phosphoribosyltransferase [...   264   4e-69
pdb|1R3U|A  Chain A, Crystal Structure Of Hypoxanthine-Guani...   264   4e-69
ref|NP_784322.1|  hypoxanthine-guanine phosphoribosyltransfe...   264   4e-69
ref|XP_001463947.1|  HGPRT,hypoxanthine-guanine phosphoribos...   263   5e-69
ref|YP_001451359.1|  hypoxanthine phosphoribosyltransferase ...   263   5e-69
ref|YP_001717770.1|  hypoxanthine phosphoribosyltransferase ...   263   5e-69
ref|NP_765828.1|  hypoxanthine-guanine phosphoribosyltransfe...   263   5e-69
ref|ZP_02431763.1|  hypothetical protein CLOSCI_01994 [Clost...   263   5e-69
ref|YP_645559.1|  hypoxanthine phosphoribosyltransferase [Ru...   263   6e-69
ref|ZP_03939360.1|  hypoxanthine phosphoribosyltransferase [...   263   6e-69
ref|YP_001708669.1|  hypoxanthine phosphoribosyltransferase ...   263   6e-69
ref|ZP_01772665.1|  Hypothetical protein COLAER_01679 [Colli...   263   7e-69
gb|ABY56069.1|  hypoxanthine phosphoribosyltransferase [uncu...   263   7e-69
ref|YP_001034033.1|  Hypoxanthine guanine phosphoribosyltran...   263   7e-69
ref|ZP_01967905.1|  hypothetical protein RUMTOR_01471 [Rumin...   263   8e-69
ref|XP_001683025.1|  hypoxanthine-guanine phosphoribosyltran...   262   8e-69
ref|YP_001095267.1|  hypoxanthine phosphoribosyltransferase ...   262   8e-69
ref|ZP_02692325.1|  hypoxanthine phosphoribosyltransferase [...   262   8e-69
ref|ZP_01074449.1|  hypoxanthine-guanine phosphoribosyltrans...   262   9e-69
ref|YP_964712.1|  hypoxanthine phosphoribosyltransferase [Sh...   262   9e-69
ref|YP_001672979.1|  hypoxanthine phosphoribosyltransferase ...   262   1e-68
ref|NP_623929.1|  Hypoxanthine-guanine phosphoribosyltransfe...   262   1e-68
ref|ZP_00156993.1|  COG0634: Hypoxanthine-guanine phosphorib...   262   1e-68
ref|NP_719339.1|  hypoxanthine phosphoribosyltransferase [Sh...   262   1e-68
ref|XP_638364.1|  hypoxanthine phosphoribosyltransferase [Di...   262   2e-68
ref|ZP_02961601.2|  hypothetical protein PROSTU_03641 [Provi...   261   2e-68
ref|ZP_03952458.1|  hypoxanthine phosphoribosyltransferase [...   261   2e-68
ref|YP_001331506.1|  hypoxanthine phosphoribosyltransferase ...   261   2e-68
ref|YP_248814.1|  hypoxanthine-guanine phosphoribosyltransfe...   261   2e-68
ref|ZP_03823286.1|  hypoxanthine phosphoribosyltransferase [...   261   3e-68
gb|EEJ83385.1|  hypoxanthine phosphoribosyltransferase [Kyto...   260   3e-68
ref|NP_245058.1|  hypoxanthine-guanine phosphoribosyltransfe...   260   3e-68
ref|ZP_01791303.1|  hypoxanthine-guanine phosphoribosyltrans...   260   3e-68
ref|YP_001664305.1|  hypoxanthine phosphoribosyltransferase ...   260   4e-68
ref|YP_145914.1|  hypoxanthine-guanine phosphoribosyltransfe...   260   4e-68
pdb|1PZM|A  Chain A, Crystal Structure Of Hgprt-Ase From Lei...   260   4e-68
ref|YP_001293064.1|  hypoxanthine-guanine phosphoribosyltran...   260   5e-68
emb|CAO80713.1|  Hypoxanthine-guanine phosphoribosyltransfer...   260   5e-68
ref|YP_001049118.1|  hypoxanthine phosphoribosyltransferase ...   260   6e-68
ref|ZP_03942372.1|  hypoxanthine phosphoribosyltransferase [...   260   6e-68
ref|YP_001140676.1|  hypoxanthine phosphoribosyltransferase ...   259   7e-68
ref|YP_001500550.1|  hypoxanthine phosphoribosyltransferase ...   259   7e-68
ref|YP_605052.1|  hypoxanthine phosphoribosyltransferase [De...   259   8e-68
ref|YP_001504671.1|  hypoxanthine phosphoribosyltransferase ...   259   8e-68
ref|ZP_03891750.1|  hypoxanthine phosphoribosyltransferase [...   259   8e-68
ref|YP_718674.1|  hypoxanthine phosphoribosyltransferase (HP...   259   9e-68
ref|YP_087875.1|  hypoxanthine-guanine phosphoribosyltransfe...   259   1e-67
gb|EEK06649.1|  hypoxanthine phosphoribosyltransferase [Brac...   259   1e-67
ref|XP_001691549.1|  hypothetical protein CHLREDRAFT_145152 ...   259   1e-67
ref|NP_387949.1|  hypoxanthine-guanine phosphoribosyltransfe...   259   1e-67
ref|ZP_02083316.1|  hypothetical protein CLOBOL_00837 [Clost...   259   1e-67
ref|YP_858016.1|  hypoxanthine phosphoribosyltransferase [Ae...   258   1e-67
ref|YP_001167250.1|  hypoxanthine phosphoribosyltransferase ...   258   2e-67
ref|ZP_01747148.1|  hypoxanthine phosphoribosyltransferase [...   257   3e-67
ref|ZP_03958961.1|  hypoxanthine phosphoribosyltransferase [...   257   4e-67
pdb|2GEB|A  Chain A, Crystal Structure Of The Thermoanaeroba...   257   4e-67
ref|YP_002786116.1|  putative Hypoxanthine phosphoribosyltra...   257   4e-67
ref|YP_352844.1|  Hypoxanthine-guanine phosphoribosyltransfe...   257   4e-67
ref|ZP_00874757.1|  Hypoxanthine phosphoribosyl transferase ...   257   4e-67
ref|ZP_01003606.1|  hypoxanthine phosphoribosyltransferase [...   257   5e-67
ref|YP_064185.1|  hypoxanthine phosphoribosyltransferase [De...   257   5e-67
ref|YP_001197388.1|  Hypoxanthine-guanine phosphoribosyltran...   257   5e-67
ref|YP_001124193.1|  Hypoxanthine-guanine phosphoribosyltran...   256   7e-67
ref|XP_001564804.1|  hypoxanthine-guanine phosphoribosyltran...   256   8e-67
ref|YP_926648.1|  Hypoxanthine phosphoribosyltransferase [Sh...   256   9e-67
ref|YP_001419748.1|  HprT [Bacillus amyloliquefaciens FZB42]...   255   1e-66
ref|NP_847264.1|  hypoxanthine-guanine phosphoribosyltransfe...   255   1e-66
ref|YP_001475642.1|  Hypoxanthine phosphoribosyltransferase ...   255   1e-66
ref|ZP_01448574.1|  hypoxanthine phosphoribosyltransferase [...   255   1e-66
ref|YP_805009.1|  Hypoxanthine-guanine phosphoribosyltransfe...   255   1e-66
sp|P37171|HPRT_RHOCA  Hypoxanthine-guanine phosphoribosyltra...   255   2e-66
ref|YP_001089202.1|  putative phosphoribosyltransferase [Clo...   255   2e-66
ref|ZP_03991579.1|  hypoxanthine phosphoribosyltransferase [...   255   2e-66
ref|YP_001762172.1|  hypoxanthine phosphoribosyltransferase ...   255   2e-66
Sequences not found previously or not previously below threshold:

>ref|ZP_01666882.1| hypoxanthine phosphoribosyltransferase [Thermosinus carboxydivorans
           Nor1]
 gb|EAX47240.1| hypoxanthine phosphoribosyltransferase [Thermosinus carboxydivorans
           Nor1]
          Length = 179

 Score =  300 bits (769), Expect = 5e-80,   Method: Composition-based stats.
 Identities = 68/187 (36%), Positives = 112/187 (59%), Gaps = 10/187 (5%)

Query: 8   DFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRIL 67
           +    +L +  +L  R+R + ++I+ DY+          ++++ VLRG+ +F AD+ R +
Sbjct: 3   EDIQEILLSSEQLSARIREMGRQISADYAG-------KEILMIGVLRGAVIFMADLARAI 55

Query: 68  GDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVD 127
               VP  ++F+  SSYG  T S G V +  D   D+ GKH+L++EDI+D+ LTL  ++D
Sbjct: 56  D---VPVALDFMAVSSYGASTTSSGVVRILKDLDEDVEGKHLLIVEDIIDSGLTLNYLLD 112

Query: 128 SLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
           +L+  +PASIK    ++KP  RK+    +Y    +P+ FVVGYGLDY + YR +  + IL
Sbjct: 113 NLRSRKPASIKICTLLNKPERRKVDVQVDYNGFTIPDHFVVGYGLDYAEKYRNLPFIGIL 172

Query: 188 KPSVYET 194
           KP  Y++
Sbjct: 173 KPEAYKS 179
>ref|YP_001113711.1| hypoxanthine phosphoribosyltransferase [Desulfotomaculum reducens
           MI-1]
 gb|ABO50886.1| hypoxanthine phosphoribosyltransferase [Desulfotomaculum reducens
           MI-1]
          Length = 179

 Score =  297 bits (763), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 67/188 (35%), Positives = 113/188 (60%), Gaps = 10/188 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           +     +L  E +++ R++ + Q+I  DY           +++V +L+G+ +F AD+VR 
Sbjct: 2   HPHVEKILLEENQINERIQQLGQQITQDYQG-------KDILMVGILKGAMIFLADLVR- 53

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
             +  VPT  +F+  SSYG  T S G V +  D    I GKH++++EDI+DT LTL+ +V
Sbjct: 54  --NIEVPTFFDFMAVSSYGAGTVSSGVVRILKDLDKSIEGKHIIIVEDIVDTGLTLQYMV 111

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           +++K   PAS+K    +DKP  RK+    +Y    +P+ FVVG+GLDY++ YR +  + +
Sbjct: 112 ENIKSRGPASVKVCTLLDKPDRRKVEVPIDYNGFQIPDEFVVGFGLDYNERYRNLPYIAV 171

Query: 187 LKPSVYET 194
           LKP +Y++
Sbjct: 172 LKPEIYQS 179
>gb|EEJ98066.1| hypoxanthine phosphoribosyltransferase [Thermomonospora curvata DSM
           43183]
          Length = 186

 Score =  297 bits (762), Expect = 3e-79,   Method: Composition-based stats.
 Identities = 71/184 (38%), Positives = 102/184 (55%), Gaps = 10/184 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
              SVL T+ EL  ++R +A  I  DY+          L++V VL+G+ +  AD+ R L 
Sbjct: 9   DLASVLITQEELQAKIRELAAEIDADYAG-------RDLLLVGVLKGAVMVMADLARALH 61

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
               P  ++++  SSYG  T+S G V +  D   DI G+HVL++EDI+D+ LTL  +V +
Sbjct: 62  S---PVSMDWMAVSSYGSGTRSSGVVRILKDLDTDITGRHVLIVEDIIDSGLTLSWLVSN 118

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           L    PAS++    + KP   +      YV  D+PN FVVGYGLDY + YR +  V  L 
Sbjct: 119 LASRNPASLEICALLRKPEAAQAEIDVRYVGFDIPNEFVVGYGLDYAEKYRNLPFVGTLA 178

Query: 189 PSVY 192
           P VY
Sbjct: 179 PHVY 182
>ref|NP_469596.1| fusion protein, N-terminal part similar to Bacillus subtilis YacA
           protein, C-terminal part similar to hypoxanthine-guanine
           phosphoribosyltransferase [Listeria innocua Clip11262]
 sp|Q92F56|TILS_LISIN Bifunctional protein tilS/hprT [Includes: tRNA(Ile)-lysidine
           synthase (tRNA(Ile)-lysidine synthetase)
           (tRNA(Ile)-2-lysyl-cytidine synthase);
           Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
           (HGPRTase)]
 emb|CAC95484.1| fusion protein, N-terminal part similar to B. subtilis YacA
           protein, C-terminal part similar to hypoxanthine-guanine
           phosphoribosyltransferase [Listeria innocua]
          Length = 648

 Score =  291 bits (747), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 66/186 (35%), Positives = 106/186 (56%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+++ 
Sbjct: 471 HNDIQKVLISEDELQEKIRELGRELTAEYEGRNP-------LVVGVLKGATPFMTDLLKR 523

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +  +     ++F+  SSYG+ T S G V +  D    + G+ VL++EDI+D+  TL  +V
Sbjct: 524 IDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLIIEDIIDSGRTLSYLV 580

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  + I
Sbjct: 581 DLIKYRKAKSVKLVTLLDKPAGRNVAIEADYVGFVVPNEFVVGYGLDYAERYRNLPYIGI 640

Query: 187 LKPSVY 192
           LKP +Y
Sbjct: 641 LKPEIY 646
>ref|YP_359913.1| hypoxanthine phosphoribosyltransferase [Carboxydothermus
           hydrogenoformans Z-2901]
 gb|ABB13649.1| hypoxanthine phosphoribosyltransferase [Carboxydothermus
           hydrogenoformans Z-2901]
          Length = 179

 Score =  291 bits (746), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 62/186 (33%), Positives = 107/186 (57%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           +     +L +E E+  +++ + Q+I+ DY+          L++V +LRG+ +F +D++R 
Sbjct: 2   HQDIAEILISEEEIRAKVKELGQQISRDYAG-------QDLLLVGILRGAMLFMSDLMR- 53

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
             +  +P  ++F+  SSYG  T + G V V  D    I G++VL++EDI+DT LTL  + 
Sbjct: 54  --EIDIPINIDFMVVSSYGSGTTTSGEVRVLKDLDRGIEGRNVLLIEDIVDTGLTLNYLT 111

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
             L    P S+K    ++KP  R++    +Y    +P+ FVVGYGLDY++ YR +  + +
Sbjct: 112 KYLANRHPKSLKVCTLLNKPSRRRVEVKVDYNGFIIPDKFVVGYGLDYNEYYRNLPYIGV 171

Query: 187 LKPSVY 192
           LKP +Y
Sbjct: 172 LKPEIY 177
>ref|XP_816916.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi strain CL Brener]
 gb|EAN95065.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi]
          Length = 241

 Score =  291 bits (745), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 104/201 (51%), Positives = 145/201 (72%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 24  EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 83

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+DTALTL  +
Sbjct: 84  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYL 143

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 144 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 203

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY       ++++ A+
Sbjct: 204 VLRPEVYAEREAARQKKQRAI 224
>ref|ZP_02276207.1| hypothetical protein LmonFS_00952 [Listeria monocytogenes FSL
           J1-194]
          Length = 648

 Score =  290 bits (744), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 67/186 (36%), Positives = 106/186 (56%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+++ 
Sbjct: 471 HNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDLLKR 523

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL  +V
Sbjct: 524 VDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLSYLV 580

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  + I
Sbjct: 581 DLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPYIGI 640

Query: 187 LKPSVY 192
           LKP +Y
Sbjct: 641 LKPEIY 646
>ref|ZP_01514399.1| hypoxanthine phosphoribosyltransferase [Chloroflexus aggregans DSM
           9485]
 gb|EAV11938.1| hypoxanthine phosphoribosyltransferase [Chloroflexus aggregans DSM
           9485]
          Length = 180

 Score =  290 bits (744), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 63/186 (33%), Positives = 102/186 (54%), Gaps = 9/186 (4%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           +     +L +E ++  R+  +   I +DY           L++V VL+G  +F  D+ R 
Sbjct: 2   HQDIDYILISEEQIKQRVAELGAAITNDYRAIG------DLLLVGVLKGCAMFMVDLARA 55

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +    +P  ++F+  +SYG  T+S G V +  D   DI  +HVL++EDI+D+ LTL  + 
Sbjct: 56  ID---LPLAIDFIAVASYGASTESSGVVRLMKDLDTDISNRHVLIVEDIIDSGLTLAYLR 112

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
             L +  PAS++    ++KP  R      +YV  D+PN FVVGYGLDY + YR +  + +
Sbjct: 113 AQLLRRNPASLRICTLLNKPERRTADVPVDYVGFDIPNAFVVGYGLDYAERYRNLPFIGV 172

Query: 187 LKPSVY 192
           L+P VY
Sbjct: 173 LRPEVY 178
>ref|YP_012840.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 4b F2365]
 sp|Q724J4|TILS_LISMF Bifunctional protein tilS/hprT [Includes: tRNA(Ile)-lysidine
           synthase (tRNA(Ile)-lysidine synthetase)
           (tRNA(Ile)-2-lysyl-cytidine synthase);
           Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
           (HGPRTase)]
 gb|AAT03017.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 4b F2365]
          Length = 648

 Score =  290 bits (744), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 67/186 (36%), Positives = 106/186 (56%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+++ 
Sbjct: 471 HNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDLLKR 523

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL  +V
Sbjct: 524 VDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLSYLV 580

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  + I
Sbjct: 581 DLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPYIGI 640

Query: 187 LKPSVY 192
           LKP +Y
Sbjct: 641 LKPEIY 646
>ref|ZP_02686823.1| hypothetical protein LmonFSL_00295 [Listeria monocytogenes FSL
           J2-071]
          Length = 648

 Score =  290 bits (744), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 67/186 (36%), Positives = 106/186 (56%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+++ 
Sbjct: 471 HNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDLLKR 523

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL  +V
Sbjct: 524 VDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLSYLV 580

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  + I
Sbjct: 581 DLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPYIGI 640

Query: 187 LKPSVY 192
           LKP +Y
Sbjct: 641 LKPEIY 646
>ref|ZP_01926199.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes FSL N1-017]
 gb|EBA30198.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes FSL N1-017]
          Length = 648

 Score =  290 bits (744), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 67/186 (36%), Positives = 106/186 (56%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+++ 
Sbjct: 471 HNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDLLKR 523

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL  +V
Sbjct: 524 VDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLSYLV 580

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  + I
Sbjct: 581 DLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPYIGI 640

Query: 187 LKPSVY 192
           LKP +Y
Sbjct: 641 LKPEIY 646
>ref|NP_463750.1| fusion protein, N-terminal part similar to B. subtilis YacA
           protein, C-terminal part similar to hypoxanthine-guanine
           phosphoribosyltransferase [Listeria monocytogenes EGD-e]
 ref|ZP_00234818.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 1/2a F6854]
 ref|ZP_01931638.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes F6900]
 ref|ZP_01936543.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes J0161]
 ref|ZP_01937061.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes J2818]
 sp|Q8YAC7|TILS_LISMO Bifunctional protein tilS/hprT [Includes: tRNA(Ile)-lysidine
           synthase (tRNA(Ile)-lysidine synthetase)
           (tRNA(Ile)-2-lysyl-cytidine synthase);
           Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
           (HGPRTase)]
 emb|CAD00746.1| fusion protein, N-terminal part similar to B. subtilis YacA
           protein, C-terminal part similar to hypoxanthine-guanine
           phosphoribosyltransferase [Listeria monocytogenes]
 gb|EAL05331.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 1/2a F6854]
 gb|EBA19187.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes J0161]
 gb|EBA27147.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes J2818]
 gb|EBA35646.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes F6900]
          Length = 648

 Score =  290 bits (744), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 67/186 (36%), Positives = 106/186 (56%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+++ 
Sbjct: 471 HNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDLLKR 523

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL  +V
Sbjct: 524 VDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLSYLV 580

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  + I
Sbjct: 581 DLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPYIGI 640

Query: 187 LKPSVY 192
           LKP +Y
Sbjct: 641 LKPEIY 646
>ref|ZP_00230936.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 4b H7858]
 ref|ZP_01942761.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes HPB2262]
 gb|AAM74001.1|AF467001_2 YacA/HprT-like protein [Listeria monocytogenes]
 gb|EAL09226.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 4b H7858]
 gb|EBA38300.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes HPB2262]
          Length = 648

 Score =  290 bits (744), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 67/186 (36%), Positives = 106/186 (56%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+++ 
Sbjct: 471 HNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDLLKR 523

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL  +V
Sbjct: 524 VDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLSYLV 580

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  + I
Sbjct: 581 DLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPYIGI 640

Query: 187 LKPSVY 192
           LKP +Y
Sbjct: 641 LKPEIY 646
>ref|NP_627611.1| hypoxanthine phosphoribosyltransferase [Streptomyces coelicolor
           A3(2)]
 emb|CAB42758.1| putative hypoxanthine phosphoribosyltransferase [Streptomyces
           coelicolor A3(2)]
          Length = 187

 Score =  290 bits (744), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 69/184 (37%), Positives = 105/184 (57%), Gaps = 10/184 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VL T+ E+  ++  +A +I  +Y+          L++V VL+G+ +  AD+ R L 
Sbjct: 12  DLEKVLITKEEIDAKLAELAAKIDAEYAG-------KDLLIVGVLKGAVMVMADLARTLS 64

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
               P  ++++  SSYG  T+S G V +  D   DI+G+HVL++EDI+D+ LTL  ++ +
Sbjct: 65  ---TPVTMDWMAVSSYGAGTQSSGVVRILKDLDTDIKGRHVLIVEDIIDSGLTLSWLISN 121

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           L   EPAS+K    + KP   K+    E+V  D+PN FVVGYGLDY + YR +  V  L 
Sbjct: 122 LGSREPASLKVCTLLRKPDAAKVAIDVEWVGFDIPNEFVVGYGLDYAEKYRNLPFVGTLA 181

Query: 189 PSVY 192
           P VY
Sbjct: 182 PHVY 185
>ref|XP_822405.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
 gb|EAN77577.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
          Length = 210

 Score =  290 bits (743), Expect = 5e-77,   Method: Composition-based stats.
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT
Sbjct: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL
Sbjct: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE
Sbjct: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180

Query: 181 VRDVVILKPSVYETWGKELERRKAAVKAKL 210
           VRDVVILKPSVYETWGKELERRKAAVKAKL
Sbjct: 181 VRDVVILKPSVYETWGKELERRKAAVKAKL 210
>ref|NP_825842.1| hypoxanthine phosphoribosyltransferase [Streptomyces avermitilis
           MA-4680]
 dbj|BAC72377.1| putative hypoxanthine phosphoribosyltransferase [Streptomyces
           avermitilis MA-4680]
          Length = 186

 Score =  290 bits (743), Expect = 5e-77,   Method: Composition-based stats.
 Identities = 70/184 (38%), Positives = 106/184 (57%), Gaps = 10/184 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
              SVL T+ E+  ++  +A +I  +Y+          L++V VL+G+ +  AD+ R L 
Sbjct: 11  DLKSVLITKEEIDAKLAELAAKIDAEYAG-------KDLLIVGVLKGAVMVMADLARALS 63

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
               P  ++++  SSYG  T+S G V +  D   DI+GKHVL++EDI+D+ LTL  ++ +
Sbjct: 64  ---TPVTMDWMAVSSYGAGTQSSGVVRILKDLDTDIKGKHVLIVEDIIDSGLTLSWLISN 120

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           L   EPAS+K    + KP   K+    E+V  D+PN FV+GYGLDY + YR +  V  L 
Sbjct: 121 LGSREPASLKVCTLLRKPEAAKVAIDVEWVGFDIPNEFVIGYGLDYAEKYRNLPFVGTLA 180

Query: 189 PSVY 192
           P VY
Sbjct: 181 PHVY 184
>ref|ZP_01928838.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes FSL N3-165]
 gb|EBA33086.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes FSL N3-165]
          Length = 648

 Score =  290 bits (743), Expect = 5e-77,   Method: Composition-based stats.
 Identities = 67/186 (36%), Positives = 106/186 (56%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+++ 
Sbjct: 471 HNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDLLKR 523

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL  +V
Sbjct: 524 VDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLSYLV 580

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  + I
Sbjct: 581 DLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPYIGI 640

Query: 187 LKPSVY 192
           LKP +Y
Sbjct: 641 LKPEIY 646
>ref|ZP_01942347.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes 10403S]
 gb|EBA21850.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes 10403S]
          Length = 648

 Score =  289 bits (742), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 67/186 (36%), Positives = 106/186 (56%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+++ 
Sbjct: 471 HNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDLLKR 523

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL  +V
Sbjct: 524 VDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLSYLV 580

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  + I
Sbjct: 581 DLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPYIGI 640

Query: 187 LKPSVY 192
           LKP +Y
Sbjct: 641 LKPEIY 646
>pdb|1TC2|A Chain A, Ternary Substrate Complex Of The Hypoxanthine
           Phosphoribosyltransferase From Trypanosoma Cruzi
 pdb|1TC2|B Chain B, Ternary Substrate Complex Of The Hypoxanthine
           Phosphoribosyltransferase From Trypanosoma Cruzi
 pdb|1P19|A Chain A, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
 pdb|1P19|B Chain B, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
 pdb|1P19|C Chain C, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
 pdb|1P19|D Chain D, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, In Complex With The Product Imp
          Length = 221

 Score =  289 bits (742), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 104/201 (51%), Positives = 145/201 (72%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+DTALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY       ++++ A+
Sbjct: 184 VLRPEVYAEREAARQKKQRAI 204
>ref|XP_822398.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
 sp|Q07010|HPRT_TRYBB Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase)
 gb|AAA16328.1| hypoxanthine-guanine phosphoribosyltransferase
 gb|EAN77570.1| hypoxanthine-guanine phosphoribosyltransferase [Trypanosoma brucei]
          Length = 210

 Score =  289 bits (742), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 205/209 (98%), Positives = 208/209 (99%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLV+VSVL+GSFVFT
Sbjct: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVIVSVLKGSFVFT 60

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL
Sbjct: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE
Sbjct: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180

Query: 181 VRDVVILKPSVYETWGKELERRKAAVKAK 209
           VRDVVILKPSVYETWGKELERRKAA +AK
Sbjct: 181 VRDVVILKPSVYETWGKELERRKAAGEAK 209
>pdb|1TC1|A Chain A, A 1.4 Angstrom Crystal Structure For The Hypoxanthine
           Phosphoribosyltransferase Of Trypanosoma Cruzi
 pdb|1TC1|B Chain B, A 1.4 Angstrom Crystal Structure For The Hypoxanthine
           Phosphoribosyltransferase Of Trypanosoma Cruzi
          Length = 220

 Score =  289 bits (742), Expect = 7e-77,   Method: Composition-based stats.
 Identities = 104/201 (51%), Positives = 145/201 (72%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 3   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 62

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+DTALTL  +
Sbjct: 63  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYL 122

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 123 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 182

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY       ++++ A+
Sbjct: 183 VLRPEVYAEREAARQKKQRAI 203
>pdb|1P17|A Chain A, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P17|B Chain B, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P17|C Chain C, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P17|D Chain D, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Complexed With The Product Imp
 pdb|1P18|A Chain A, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Ternary Substrates Complex
 pdb|1P18|B Chain B, Hypoxanthine Phosphoribosyltransferase From Trypanosoma
           Cruzi, K68r Mutant, Ternary Substrates Complex
          Length = 221

 Score =  289 bits (740), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 105/201 (52%), Positives = 145/201 (72%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVLRGSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLRGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+DTALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY       ++++ A+
Sbjct: 184 VLRPEVYAEREAARQKKQRAI 204
>ref|YP_001213102.1| hypoxanthine-guanine phosphoribosyltransferase [Pelotomaculum
           thermopropionicum SI]
 dbj|BAF60733.1| hypoxanthine-guanine phosphoribosyltransferase [Pelotomaculum
           thermopropionicum SI]
          Length = 181

 Score =  289 bits (740), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 73/186 (39%), Positives = 109/186 (58%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           +     +LFTE E+  R+  + + I+ DY+          L+VV +L+G+ +F AD+VR 
Sbjct: 2   HPDGERILFTEEEIRARVAEMGREISRDYAG-------RELLVVGILKGAMIFLADLVRS 54

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +    VP   +F+  SSYG  TKS G V +  D    I G+HVL++EDI+DT LTL  +V
Sbjct: 55  IT---VPAFFDFIAVSSYGTSTKSSGAVRILKDLDRGIEGRHVLIVEDIVDTGLTLNYLV 111

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D+L    PAS+K    +DKP  R+ P    Y    +P+ FVVGYGLDY++ YR +  +++
Sbjct: 112 DNLTARGPASLKVCTLLDKPSRRQKPVEIHYNGFTIPDEFVVGYGLDYNECYRNLPYIMV 171

Query: 187 LKPSVY 192
           L P V+
Sbjct: 172 LSPRVF 177
>ref|ZP_03924809.1| hypoxanthine phosphoribosyltransferase [Actinomyces coleocanis DSM
           15436]
 gb|EEH64610.1| hypoxanthine phosphoribosyltransferase [Actinomyces coleocanis DSM
           15436]
          Length = 183

 Score =  288 bits (738), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 67/184 (36%), Positives = 102/184 (55%), Gaps = 10/184 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               +  TE ++  R++ +A  I  DY+          L++V VLRG+ +  AD+ R L 
Sbjct: 9   DLQEIFLTEEQIRARIQEMAAEIDRDYAG-------KDLLLVGVLRGAIMVMADLSRALK 61

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
           +   P  ++++  SSYG  TKS G V +  D   DI G+HVL++EDI+D+ LTL  + ++
Sbjct: 62  N---PLHMDWMAVSSYGSGTKSSGVVRILKDLDTDISGRHVLIVEDIIDSGLTLSWLKEN 118

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           L    PAS++    + KP   ++    +YV  D+ N FVVGYGLDY + YR +  V  L 
Sbjct: 119 LSSRGPASVEIATFLRKPEAVRVDIDVKYVGFDIANEFVVGYGLDYAEKYRNLPFVGTLA 178

Query: 189 PSVY 192
           P VY
Sbjct: 179 PHVY 182
>ref|YP_848383.1| conserved hypothetical/hypoxanthine phosphoribosyltransferase,
           fusion protein [Listeria welshimeri serovar 6b str.
           SLCC5334]
 emb|CAK19600.1| unnamed protein product [Listeria welshimeri serovar 6b str.
           SLCC5334]
          Length = 648

 Score =  288 bits (738), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 66/186 (35%), Positives = 106/186 (56%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+++ 
Sbjct: 471 HNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDLLKR 523

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL  +V
Sbjct: 524 VDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLSYLV 580

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  + +
Sbjct: 581 DLIKYRKAKSVKLVTLLDKPAGRNVAIEADYVGFVVPNEFVVGYGLDYAERYRNLPYIGV 640

Query: 187 LKPSVY 192
           LKP +Y
Sbjct: 641 LKPEIY 646
>ref|ZP_02091227.1| hypothetical protein FAEPRAM212_01498 [Faecalibacterium prausnitzii
           M21/2]
 gb|EDP21677.1| hypothetical protein FAEPRAM212_01498 [Faecalibacterium prausnitzii
           M21/2]
          Length = 180

 Score =  288 bits (738), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 76/189 (40%), Positives = 110/189 (58%), Gaps = 11/189 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           +D   +VL +E +L  ++  +  +I+ DY+  N       LV+VS+L+GS VF AD++R 
Sbjct: 2   HDDIKTVLVSEEQLKAKVAELGAQISRDYAGKN-------LVLVSILKGSVVFMADLMRA 54

Query: 67  LGDFGVPTRVEFLRASSYGHD-TKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
           +    +P  ++F+  SSYG   T + G V +  D   D+ GK VL++EDILDT +TL  +
Sbjct: 55  VS---IPCNIDFMVVSSYGGSNTTTSGLVKIIKDLDGDLSGKDVLIVEDILDTGVTLSNL 111

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
           V  LK   P S+K    +DKP  RK     +Y    VP+ FVVGYGLDYD+ YR +  V 
Sbjct: 112 VPMLKMRNPNSVKICTILDKPSRRKADIQPDYEGFQVPDEFVVGYGLDYDEKYRNLPYVG 171

Query: 186 ILKPSVYET 194
           +LKP VY  
Sbjct: 172 VLKPEVYTK 180
>ref|XP_813396.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi strain CL Brener]
 gb|AAB46391.1| hypoxanthine-guanine phosphoribosyltransferase
 gb|EAN91545.1| hypoxanthine-guanine phosphoribosyltransferase, putative
           [Trypanosoma cruzi]
          Length = 221

 Score =  288 bits (738), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 104/201 (51%), Positives = 144/201 (71%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR+  VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIMEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+DTALTL  +
Sbjct: 64  ALSDFNVPVRMEFICVSSYGEGVTSSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY       ++++ A+
Sbjct: 184 VLRPEVYAEREAARQKKQRAI 204
>ref|ZP_02037643.1| hypothetical protein BACCAP_03261 [Bacteroides capillosus ATCC
           29799]
 gb|EDM98927.1| hypothetical protein BACCAP_03261 [Bacteroides capillosus ATCC
           29799]
          Length = 182

 Score =  288 bits (738), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 75/184 (40%), Positives = 106/184 (57%), Gaps = 10/184 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VLF+E EL  R+  +A  I  DY+           +++SVLRGSFVF AD+ R + 
Sbjct: 5   DIERVLFSEEELDKRVSEIAAEINRDYAG-------KEPMLISVLRGSFVFMADLTRKIE 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
              VP  ++F+  SSYG  T S G+V +  D   DI GK ++V+EDILD+  TL  +++ 
Sbjct: 58  ---VPCTIDFMSVSSYGKGTTSSGQVQITKDLSDDIEGKDIIVVEDILDSGNTLSYLLEL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           L+  +PAS+K    +DKP  R      +Y    +P+ FVVGYGLDY + YR +  + ILK
Sbjct: 115 LRARKPASMKLCTLLDKPDRRVKEVHVDYSGFTIPDEFVVGYGLDYAEKYRNLPYIGILK 174

Query: 189 PSVY 192
           P VY
Sbjct: 175 PRVY 178
>ref|YP_001274703.1| hypoxanthine phosphoribosyltransferase [Roseiflexus sp. RS-1]
 gb|ABQ88753.1| hypoxanthine phosphoribosyltransferase [Roseiflexus sp. RS-1]
          Length = 682

 Score =  287 bits (737), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 63/190 (33%), Positives = 101/190 (53%), Gaps = 9/190 (4%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           +D    +L T  ++  R+R +  +I  DY       L   L      +G  +F  D+ R 
Sbjct: 502 HDDMAKILLTAEQIQERVRALGAQITTDYRPLGDLLLVGVL------KGCAMFMVDLARA 555

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +    +P  ++F+  SSYG  T+S G V +  D   DI G+HVL++EDI+D+ LTL  + 
Sbjct: 556 ID---LPLGMDFIATSSYGKTTESSGVVRMLKDLDTDIAGRHVLIVEDIIDSGLTLAYLR 612

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
             L +  PAS++    ++KP  R+     +Y+  D+PN FVVGYGLD+D+ YR +  + +
Sbjct: 613 GHLLRRNPASLRICALLNKPERRRADIPIDYLGFDIPNEFVVGYGLDFDEKYRNLPYIGV 672

Query: 187 LKPSVYETWG 196
           L   +Y T  
Sbjct: 673 LHERIYHTTA 682
>ref|YP_002769603.1| hypoxanthine-guanine phosphoribosyltransferase [Brevibacillus
           brevis NBRC 100599]
 dbj|BAH41099.1| hypoxanthine-guanine phosphoribosyltransferase [Brevibacillus
           brevis NBRC 100599]
          Length = 179

 Score =  287 bits (736), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 66/186 (35%), Positives = 111/186 (59%), Gaps = 10/186 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               +L +E ++  ++R + + +A +Y + N        +V+ VL+G+ +F AD++R + 
Sbjct: 4   DIEKILLSEEDIAGKVRELGETLAAEYKDKNP-------LVICVLKGAVIFMADLIRHMS 56

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
              +P  ++F+  SSYG  T+S G V +  D    +  +HVLV+EDI+D+ LTL  +V+ 
Sbjct: 57  ---IPCEMDFMAVSSYGSGTESSGMVKILKDLDTSVENRHVLVVEDIMDSGLTLSRLVEL 113

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           L+  E AS+K +  ++KP  RK+  + +Y   DVP+ FVVGYGLDY + YR +  + +LK
Sbjct: 114 LRHREAASVKVVTLLNKPERRKVDISPDYKGYDVPDEFVVGYGLDYAEHYRNLPYIGVLK 173

Query: 189 PSVYET 194
           P VY  
Sbjct: 174 PEVYTK 179
>ref|YP_001430999.1| hypoxanthine phosphoribosyltransferase [Roseiflexus castenholzii
           DSM 13941]
 gb|ABU56981.1| hypoxanthine phosphoribosyltransferase [Roseiflexus castenholzii
           DSM 13941]
          Length = 676

 Score =  287 bits (735), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 61/190 (32%), Positives = 101/190 (53%), Gaps = 9/190 (4%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           +D    +L T  ++  R+R +  +I  DY       L   L      +G  +F  D+ R 
Sbjct: 496 HDDMAKILITAGQIQERVRALGAQITADYRPLGDLLLVGVL------KGCAMFMVDLARA 549

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +    +P  ++F+  SSYG  T+S G V +  D   DI G+HV+++EDI+D+ LTL  + 
Sbjct: 550 ID---MPLAMDFIATSSYGKTTESSGVVRMLKDLDTDIAGRHVVIVEDIIDSGLTLAYLR 606

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
             L +  PAS++    ++KP  R+     +Y+  D+PN FVVGYGLD+D+ YR +  + +
Sbjct: 607 GHLLRRNPASLRICALLNKPSRRRADIPIDYLGFDIPNEFVVGYGLDFDEKYRNLPYIGV 666

Query: 187 LKPSVYETWG 196
           L   +Y +  
Sbjct: 667 LHERIYHSTA 676
>ref|YP_001825599.1| putative hypoxanthine phosphoribosyltransferase [Streptomyces
           griseus subsp. griseus NBRC 13350]
 dbj|BAG20916.1| putative hypoxanthine phosphoribosyltransferase [Streptomyces
           griseus subsp. griseus NBRC 13350]
          Length = 184

 Score =  287 bits (735), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 68/184 (36%), Positives = 106/184 (57%), Gaps = 10/184 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
              SVL T+ E+  ++  +A +I  +Y+          L++V VL+G+ +  AD+ R L 
Sbjct: 9   DLQSVLLTKEEIDAKLVELAAKIDAEYAG-------KDLLIVGVLKGAVMVMADLARALS 61

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
               P  ++++  SSYG  T+S G V +  D   DI+GKHVL++EDI+D+ LTL  ++ +
Sbjct: 62  ---TPVTMDWMAVSSYGAGTQSSGVVRILKDLDTDIKGKHVLIVEDIIDSGLTLSWLLSN 118

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           L   EPAS++    + KP   K+    +++  D+PN FVVGYGLDY + YR +  V  L 
Sbjct: 119 LGSREPASLEVCTLLRKPDAAKVAIDVKWIGFDIPNEFVVGYGLDYAEKYRNLPFVGTLA 178

Query: 189 PSVY 192
           P VY
Sbjct: 179 PHVY 182
>ref|YP_644942.1| hypoxanthine phosphoribosyltransferase [Rubrobacter xylanophilus
           DSM 9941]
 gb|ABG05130.1| hypoxanthine phosphoribosyltransferase [Rubrobacter xylanophilus
           DSM 9941]
          Length = 189

 Score =  287 bits (735), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 66/186 (35%), Positives = 104/186 (55%), Gaps = 9/186 (4%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
                 VL    E+  +++ + ++I  DY           L++V VLRG+ +   D++R 
Sbjct: 8   MPDVQEVLIPSEEIQQKVKDLGEQITRDYR------EHRRLLLVGVLRGAVIVMGDLMRR 61

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
           +    +P  ++F+  SSYG  T S G V +  D   DI G+HVL++EDI+DT LTL  + 
Sbjct: 62  ID---LPCEIDFMEVSSYGAGTTSSGVVRILKDLEEDISGRHVLIVEDIIDTGLTLSYLR 118

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
            SL   +PAS++    + KP  R++    +Y+  ++P+ FVVGYGLDY   YR + D+ I
Sbjct: 119 RSLLARKPASLEICALLSKPARRRVELDVKYLGFEIPDEFVVGYGLDYAGCYRNLPDICI 178

Query: 187 LKPSVY 192
           LKP V+
Sbjct: 179 LKPEVF 184
>ref|ZP_02330217.1| hypothetical protein Plarl_21636 [Paenibacillus larvae subsp.
           larvae BRL-230010]
          Length = 188

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 60/185 (32%), Positives = 107/185 (57%), Gaps = 10/185 (5%)

Query: 8   DFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRIL 67
           +    V FTE ++  +++ +  ++++D+   N        +V+ VL+G+F+F AD+V+ +
Sbjct: 12  NDIQEVFFTEEQIQEKIKELGGKLSEDFKGRNP-------LVICVLKGAFIFMADLVKQM 64

Query: 68  GDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVD 127
               VP  ++F+  SSYG  TKS G V +  D    + G+ +L++EDI+D+ LTL  ++D
Sbjct: 65  T---VPLEIDFMAVSSYGASTKSSGVVKIIKDLDTSVEGRDILIVEDIIDSGLTLSYLID 121

Query: 128 SLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
            LK+    S+  +   +KP  R +    +YV   + + F+VGYGLDY + YR +  + +L
Sbjct: 122 VLKRRNAKSVSIVTLFNKPARRTVDLEPDYVGFKIDDAFIVGYGLDYAEKYRNLPFIGVL 181

Query: 188 KPSVY 192
           KP +Y
Sbjct: 182 KPEIY 186
>ref|NP_814058.1| hypoxanthine-guanine phosphoribosyltransferase [Enterococcus
           faecalis V583]
 sp|Q839B2|HPRT_ENTFA Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase)
 gb|AAO80129.1| hypoxanthine-guanine phosphoribosyltransferase [Enterococcus
           faecalis V583]
          Length = 181

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 66/187 (35%), Positives = 109/187 (58%), Gaps = 10/187 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VL ++ E+  +   + +++ ++Y   N        +VV +L+G+  F AD+ R   
Sbjct: 5   DIEKVLISKEEILAKSAELGKQLTEEYQGKNP-------LVVGILKGAVPFMADLTR--- 54

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
           +      ++F+  SSYG+ T S G V +  D   ++ G+H+L++EDI+D+  TL  +VD 
Sbjct: 55  EINTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRHILIVEDIIDSGRTLAYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            +  + AS+K +  +DKP GR +   A+YV  DVPN FVVGYGLDY ++YR +  + +LK
Sbjct: 115 FRYRKAASVKIVTLLDKPEGRVVDIKADYVGFDVPNEFVVGYGLDYAETYRNLPYIGVLK 174

Query: 189 PSVYETW 195
           P VYE+ 
Sbjct: 175 PEVYESN 181
>pdb|1I14|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamic
           Acid Mutant
 pdb|1I14|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamic
           Acid Mutant
          Length = 221

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 103/201 (51%), Positives = 144/201 (71%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI++TALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVETALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY        +++ A+
Sbjct: 184 VLRPEVYAEREAARGKKQRAI 204
>pdb|1I0L|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Asparagine
           Mutant
 pdb|1I0L|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Asparagine
           Mutant
          Length = 221

 Score =  285 bits (731), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 103/201 (51%), Positives = 144/201 (71%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI++TALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVNTALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY        +++ A+
Sbjct: 184 VLRPEVYAEREAARGKKQRAI 204
>pdb|1I0I|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamine
           Mutant
 pdb|1I0I|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Glutamine
           Mutant
          Length = 221

 Score =  284 bits (729), Expect = 2e-75,   Method: Composition-based stats.
 Identities = 103/201 (51%), Positives = 143/201 (71%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+ TALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVQTALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY        +++ A+
Sbjct: 184 VLRPEVYAEREAARGKKQRAI 204
>ref|YP_290952.1| hypoxanthine phosphoribosyl transferase [Thermobifida fusca YX]
 gb|AAZ56929.1| hypoxanthine phosphoribosyltransferase [Thermobifida fusca YX]
          Length = 184

 Score =  284 bits (728), Expect = 3e-75,   Method: Composition-based stats.
 Identities = 67/185 (36%), Positives = 104/185 (56%), Gaps = 10/185 (5%)

Query: 10  ATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILGD 69
              +L TE ++ TR R +A  I  DY+          L++V VL+G+ +  AD+ R L  
Sbjct: 10  LDKILVTEEQIRTRTRELAAEIDADYAG-------KDLLLVGVLKGAVMVMADLARELHH 62

Query: 70  FGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDSL 129
              P  ++++  SSYG  T S G V +  D   DI+G++VL++ED++D+ LTL  +V +L
Sbjct: 63  ---PCEMDWMAVSSYGAGTTSSGVVRILKDLDTDIQGRNVLIVEDVIDSGLTLSWLVGNL 119

Query: 130 KKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILKP 189
           K   PAS++    + KP    +    +YV  D+PN F+VGYGLDY + YR +  +  L P
Sbjct: 120 KSRHPASVEICTMVRKPMAFNVDLDVKYVGFDLPNEFIVGYGLDYAEKYRNLPFIATLAP 179

Query: 190 SVYET 194
            VY+ 
Sbjct: 180 HVYDD 184
>pdb|1I13|A Chain A, Analysis Of An Invariant Aspartic Acid In Hprts-Alanine
           Mutant
 pdb|1I13|B Chain B, Analysis Of An Invariant Aspartic Acid In Hprts-Alanine
           Mutant
          Length = 221

 Score =  284 bits (727), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 103/201 (51%), Positives = 143/201 (71%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
           +Y+FA  +LFTE E+ TR++ VA+RIADDY    L+P  NPLV++SVL+GSF+FTAD+ R
Sbjct: 4   EYEFAEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLKGSFMFTADLCR 63

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            L DF VP R+EF+  SSYG    S G+V +  D    I G HVL++EDI+ TALTL  +
Sbjct: 64  ALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVATALTLNYL 123

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
                   PAS+KT+V +DK  GR++PF+A+YVVA++PN FV+GYGLDYD +YRE+RD+V
Sbjct: 124 YHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYRELRDIV 183

Query: 186 ILKPSVYETWGKELERRKAAV 206
           +L+P VY        +++ A+
Sbjct: 184 VLRPEVYAEREAARGKKQRAI 204
>ref|ZP_02581448.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus B4264]
          Length = 180

 Score =  283 bits (726), Expect = 4e-75,   Method: Composition-based stats.
 Identities = 69/184 (37%), Positives = 106/184 (57%), Gaps = 10/184 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VL +E ++  ++R +   IA+DY N          + + VL+G+  F AD+++   
Sbjct: 5   DIEKVLISEEQIQEKVRELGAIIAEDYKNTVP-------LAIGVLKGAMPFMADLLKRTD 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
            +     ++F+  SSYGH T S G V +  D    + G+ +L++EDI+D+ LTL  +VD 
Sbjct: 58  TY---LEMDFMAVSSYGHSTVSTGEVKILKDLDTSVEGRDILIVEDIIDSGLTLSYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            K  +  S+K +  +DKP GRK+   A+YV   VP+ FVVGYGLDY + YR +  V +LK
Sbjct: 115 FKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVLK 174

Query: 189 PSVY 192
           PSVY
Sbjct: 175 PSVY 178
>ref|ZP_03922784.1| hypoxanthine phosphoribosyltransferase [Mobiluncus curtisii ATCC
           43063]
 gb|EEI89371.1| hypoxanthine phosphoribosyltransferase [Mobiluncus curtisii ATCC
           43063]
          Length = 184

 Score =  283 bits (726), Expect = 5e-75,   Method: Composition-based stats.
 Identities = 71/194 (36%), Positives = 103/194 (53%), Gaps = 10/194 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M+ A        VL TE ++  R+  +A  I  DY           L++V VLRG+ +  
Sbjct: 1   MDAADMGADMERVLLTEEQIQNRLTQMAAVIDKDYEGH-------ELLLVGVLRGAVMVM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R L     P +++++  SSYG  TKS G V +  D   DI+ +HVL++EDI+D+ L
Sbjct: 54  ADLARKLHS---PIQMDWMAVSSYGSGTKSSGVVRILKDLDTDIKDRHVLIVEDIIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  +  +L+    AS+     + KP   K      YV  D+PN FVVGYGLDY + YR 
Sbjct: 111 TLSWLEANLRTRGCASLNIATLLRKPDAAKAVVNPRYVGFDIPNEFVVGYGLDYAEHYRN 170

Query: 181 VRDVVILKPSVYET 194
           +  + +L P VYE 
Sbjct: 171 LPFIGLLAPHVYEK 184
>ref|ZP_00741717.1| Hypoxanthine-guanine phosphoribosyltransferase [Bacillus
           thuringiensis serovar israelensis ATCC 35646]
 ref|ZP_02587714.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus G9842]
 gb|EAO54011.1| Hypoxanthine-guanine phosphoribosyltransferase [Bacillus
           thuringiensis serovar israelensis ATCC 35646]
          Length = 180

 Score =  283 bits (725), Expect = 6e-75,   Method: Composition-based stats.
 Identities = 69/184 (37%), Positives = 106/184 (57%), Gaps = 10/184 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VL +E ++  ++R +   IA+DY N          + + VL+G+  F AD+++   
Sbjct: 5   DIEKVLISEEQIQEKVRELGAVIAEDYKNTVP-------LAIGVLKGAMPFMADLLKRTD 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
            +     ++F+  SSYGH T S G V +  D    + G+ +L++EDI+D+ LTL  +VD 
Sbjct: 58  TY---LEMDFMAVSSYGHSTVSTGEVKILKDLDTSVEGRDILIVEDIIDSGLTLSYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            K  +  S+K +  +DKP GRK+   A+YV   VP+ FVVGYGLDY + YR +  V +LK
Sbjct: 115 FKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVLK 174

Query: 189 PSVY 192
           PSVY
Sbjct: 175 PSVY 178
>ref|ZP_00603444.1| Hypoxanthine phosphoribosyl transferase [Enterococcus faecium DO]
 gb|EAN10267.1| Hypoxanthine phosphoribosyl transferase [Enterococcus faecium DO]
          Length = 181

 Score =  283 bits (725), Expect = 6e-75,   Method: Composition-based stats.
 Identities = 67/187 (35%), Positives = 110/187 (58%), Gaps = 10/187 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               +L ++ E+  R + + + + + Y N N        +VV VL+G+  F AD+VR + 
Sbjct: 5   DIERILISQEEIQVRCKELGKELTEIYQNTNP-------LVVGVLKGAVPFMADIVRSID 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
            +     ++F+  SSYG+ T S G V +  D   ++ G+ +L++EDI+D+  TL  +VD 
Sbjct: 58  TY---LELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDIIDSGRTLAYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            K  +  S+K +  +DKP GR +   A+YV  +VPN FVVGYGLDY ++YR +  + +LK
Sbjct: 115 FKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDYAEAYRNLPYIGVLK 174

Query: 189 PSVYETW 195
           PSVY++ 
Sbjct: 175 PSVYQSN 181
>ref|YP_001642956.1| hypoxanthine phosphoribosyltransferase [Bacillus weihenstephanensis
           KBAB4]
 gb|ABY41328.1| hypoxanthine phosphoribosyltransferase [Bacillus weihenstephanensis
           KBAB4]
          Length = 180

 Score =  283 bits (725), Expect = 6e-75,   Method: Composition-based stats.
 Identities = 68/184 (36%), Positives = 105/184 (57%), Gaps = 10/184 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VL +E ++  ++  +   IA+DY N          + + VL+G+  F AD+++   
Sbjct: 5   DIEKVLISEEQIQEKVHELGAVIAEDYKNTVP-------LAIGVLKGAMPFMADLLKRTD 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
            +     ++F+  SSYGH T S G V +  D    + G+ +L++EDI+D+ LTL  +VD 
Sbjct: 58  TY---LEMDFMAVSSYGHSTVSTGEVKILKDLDTSVEGRDILIVEDIIDSGLTLSYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            K  +  S+K +  +DKP GRK+   A+YV   VP+ FVVGYGLDY + YR +  V +LK
Sbjct: 115 FKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVLK 174

Query: 189 PSVY 192
           PSVY
Sbjct: 175 PSVY 178
>ref|YP_001512894.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus oremlandii
           OhILAs]
 gb|ABW18898.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus oremlandii
           OhILAs]
          Length = 180

 Score =  283 bits (725), Expect = 6e-75,   Method: Composition-based stats.
 Identities = 69/186 (37%), Positives = 113/186 (60%), Gaps = 9/186 (4%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
           Y+    VLF++ ++  +++ + + I+ DY         + LV++ VL+G+ VF AD++R 
Sbjct: 2   YNDVEEVLFSKEDIAKKVKELGEIISKDYK------ENDDLVIIGVLKGANVFMADLMR- 54

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
             +  +P  ++F+  SSYG+ T+S G V +  D   +I GKHVL++EDI+DT LTL+ + 
Sbjct: 55  --EITIPVYIDFMAVSSYGYSTESSGIVRILKDLDLEIEGKHVLIIEDIIDTGLTLKYLT 112

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D+LK     S+K    +DKP  RK     +Y+  ++P+ F+VGYG+DY + YR +  V  
Sbjct: 113 DNLKSRNTKSVKICTLLDKPVRRKCDLKVDYMGFEIPDKFIVGYGIDYGERYRNLPYVAS 172

Query: 187 LKPSVY 192
           LKP VY
Sbjct: 173 LKPEVY 178
>ref|YP_001695855.1| Hypoxanthine-guanine phosphoribosyltransferase [Lysinibacillus
           sphaericus C3-41]
 gb|ACA37725.1| Hypoxanthine-guanine phosphoribosyltransferase [Lysinibacillus
           sphaericus C3-41]
          Length = 180

 Score =  283 bits (725), Expect = 7e-75,   Method: Composition-based stats.
 Identities = 67/186 (36%), Positives = 106/186 (56%), Gaps = 10/186 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
            +    V+ TE +L  R+  +  ++ ++Y +          + V VL+G+  F  D+++ 
Sbjct: 3   QNDIEKVMITEEQLQERIADLGAQLTEEYKDAFP-------LAVGVLKGAMPFMTDLMKR 55

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
              F     ++F+  SSYG+ T S G V +  D    + G+ VL++EDI+D+ LTL  +V
Sbjct: 56  FDSF---IELDFMDVSSYGNATVSSGEVKILKDLNTSVEGRDVLIIEDIIDSGLTLSYLV 112

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D  K  +  SIK +  +DKP GRK+  +A+YV  +VP+ FVVGYGLDY + YR +  + I
Sbjct: 113 DLFKYRKAKSIKIVTLLDKPSGRKVNLSADYVGFEVPDGFVVGYGLDYAEKYRNLPYIGI 172

Query: 187 LKPSVY 192
           LKP VY
Sbjct: 173 LKPEVY 178
>ref|YP_001626350.1| hypoxanthine-guanine phosphoribosyltransferase [Renibacterium
           salmoninarum ATCC 33209]
 gb|ABY24936.1| hypoxanthine-guanine phosphoribosyltransferase [Renibacterium
           salmoninarum ATCC 33209]
          Length = 183

 Score =  282 bits (724), Expect = 9e-75,   Method: Composition-based stats.
 Identities = 66/193 (34%), Positives = 107/193 (55%), Gaps = 10/193 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M+ +        VL+T+ ++ +R+  +A ++  DY+          +++V VL+G+ +  
Sbjct: 1   MDSSDVEADLKHVLYTKEQIQSRVIELAAQVDADYAG-------RDVLLVGVLKGAVMIM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R L        ++++  SSYG  T+S G V +  D   D+ GKHVL++EDI+D+ L
Sbjct: 54  ADLARALHS---HVTMDWMAVSSYGSGTQSSGVVRILKDLETDLMGKHVLIVEDIIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  +  +L    PAS++    + KP   K+    +YV  D+PN FVVGYGLD+ + YR 
Sbjct: 111 TLSWLRANLISRGPASVEICTLLRKPAAAKVEIDVKYVGYDIPNEFVVGYGLDFAEKYRN 170

Query: 181 VRDVVILKPSVYE 193
           +  V  L P VYE
Sbjct: 171 LDFVGTLAPHVYE 183
>ref|ZP_03982713.1| Hypoxanthine phosphoribosyltransferase [Enterococcus faecium
           TX1330]
 gb|EEI59165.1| Hypoxanthine phosphoribosyltransferase [Enterococcus faecium
           TX1330]
          Length = 181

 Score =  282 bits (724), Expect = 9e-75,   Method: Composition-based stats.
 Identities = 66/187 (35%), Positives = 110/187 (58%), Gaps = 10/187 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               +L ++ E+  R + + + + + Y N N        +VV VL+G+  F AD+VR + 
Sbjct: 5   DIERILISQEEIQVRCKELGKELTEIYQNTNP-------LVVGVLKGAVPFMADIVRSID 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
            +     ++F+  SSYG+ T S G V +  D   ++ G+ +L++EDI+D+  TL  +VD 
Sbjct: 58  TY---LELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDIIDSGRTLAYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            K  +  S+K +  +DKP GR +   A+YV  +VPN FVVGYGLDY ++YR +  + +LK
Sbjct: 115 FKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDYAEAYRNLPYIGVLK 174

Query: 189 PSVYETW 195
           P+VY++ 
Sbjct: 175 PTVYQSN 181
>ref|NP_240950.1| hypoxanthine-guanine phosphoribosyltransferase [Bacillus halodurans
           C-125]
 dbj|BAB03803.1| hypoxanthine-guanine phosphoribosyltransferase [Bacillus halodurans
           C-125]
          Length = 179

 Score =  282 bits (723), Expect = 1e-74,   Method: Composition-based stats.
 Identities = 61/187 (32%), Positives = 101/187 (54%), Gaps = 10/187 (5%)

Query: 8   DFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRIL 67
           D    +L TE E+  ++  + ++I ++Y            +V+ VL+G+  F  D+ + +
Sbjct: 3   DEIQEILITEEEIQAKIVELGKQITEEYEGKFP-------LVIGVLKGAMPFMGDLTKRI 55

Query: 68  GDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVD 127
                   ++F+  SSYG  T S G V +  D    + G+ VL++EDI+D+ LTL  +++
Sbjct: 56  D---THLEMDFMDVSSYGKGTVSSGEVKIIKDLDTSVEGRDVLIVEDIIDSGLTLSYLIE 112

Query: 128 SLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
                +  S+K +  +DKP GRK+    +     VP+ FVVGYGLDY + YR +  + IL
Sbjct: 113 LFHYRKAKSVKVVTLLDKPEGRKVDLVPDMAGFTVPDAFVVGYGLDYAERYRNLPFIGIL 172

Query: 188 KPSVYET 194
           KP VYE+
Sbjct: 173 KPEVYES 179
Searching..................................................done Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|ZP_01666882.1|  hypoxanthine phosphoribosyltransferase [...   306   6e-82
gb|EEJ98066.1|  hypoxanthine phosphoribosyltransferase [Ther...   304   3e-81
ref|NP_469596.1|  fusion protein, N-terminal part similar to...   302   1e-80
ref|YP_001113711.1|  hypoxanthine phosphoribosyltransferase ...   301   2e-80
ref|ZP_02686823.1|  hypothetical protein LmonFSL_00295 [List...   301   3e-80
ref|NP_463750.1|  fusion protein, N-terminal part similar to...   301   3e-80
ref|YP_012840.1|  conserved hypothetical protein/hypoxanthin...   301   3e-80
ref|ZP_02276207.1|  hypothetical protein LmonFS_00952 [Liste...   301   3e-80
ref|ZP_01926199.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   301   3e-80
ref|ZP_00230936.1|  conserved hypothetical protein/hypoxanth...   300   3e-80
ref|ZP_01928838.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   300   4e-80
ref|ZP_01942347.1|  tRNA(Ile)-lysidine synthetase [Listeria ...   300   5e-80
ref|ZP_01514399.1|  hypoxanthine phosphoribosyltransferase [...   299   1e-79
ref|YP_848383.1|  conserved hypothetical/hypoxanthine phosph...   298   2e-79
ref|YP_359913.1|  hypoxanthine phosphoribosyltransferase [Ca...   297   2e-79
ref|YP_002769603.1|  hypoxanthine-guanine phosphoribosyltran...   297   2e-79
ref|ZP_03924809.1|  hypoxanthine phosphoribosyltransferase [...   297   5e-79
ref|NP_627611.1|  hypoxanthine phosphoribosyltransferase [St...   295   1e-78
ref|NP_825842.1|  hypoxanthine phosphoribosyltransferase [St...   295   2e-78
ref|NP_814058.1|  hypoxanthine-guanine phosphoribosyltransfe...   294   2e-78
ref|YP_001626350.1|  hypoxanthine-guanine phosphoribosyltran...   294   2e-78
ref|ZP_02037643.1|  hypothetical protein BACCAP_03261 [Bacte...   294   2e-78
ref|ZP_03922784.1|  hypoxanthine phosphoribosyltransferase [...   294   2e-78
ref|YP_001213102.1|  hypoxanthine-guanine phosphoribosyltran...   294   3e-78
ref|ZP_02091227.1|  hypothetical protein FAEPRAM212_01498 [F...   294   3e-78
ref|ZP_02330217.1|  hypothetical protein Plarl_21636 [Paenib...   294   4e-78
ref|YP_644942.1|  hypoxanthine phosphoribosyltransferase [Ru...   293   4e-78
ref|YP_001274703.1|  hypoxanthine phosphoribosyltransferase ...   293   5e-78
ref|ZP_00603444.1|  Hypoxanthine phosphoribosyl transferase ...   292   8e-78
ref|YP_290952.1|  hypoxanthine phosphoribosyl transferase [T...   292   1e-77
ref|YP_001825599.1|  putative hypoxanthine phosphoribosyltra...   292   1e-77
ref|ZP_03982713.1|  Hypoxanthine phosphoribosyltransferase [...   292   1e-77
ref|YP_001695855.1|  Hypoxanthine-guanine phosphoribosyltran...   292   1e-77
ref|ZP_02836636.1|  hypoxanthine phosphoribosyltransferase [...   292   1e-77
ref|YP_001430999.1|  hypoxanthine phosphoribosyltransferase ...   291   2e-77
ref|ZP_02581448.1|  hypoxanthine phosphoribosyltransferase [...   291   2e-77
ref|ZP_04009409.1|  hypoxanthine-guanine phosphoribosyltrans...   291   2e-77
ref|ZP_00741717.1|  Hypoxanthine-guanine phosphoribosyltrans...   291   2e-77
ref|YP_945962.1|  hypoxanthine phosphoribosyltransferase [Ar...   291   3e-77
ref|YP_001642956.1|  hypoxanthine phosphoribosyltransferase ...   290   3e-77
ref|YP_536242.1|  Hypoxanthine-guanine phosphoribosyltransfe...   290   4e-77
ref|ZP_01725398.1|  hypoxanthine-guanine phosphoribosyltrans...   290   4e-77
ref|YP_829651.1|  hypoxanthine phosphoribosyltransferase [Ar...   290   5e-77
ref|ZP_00379834.1|  COG0634: Hypoxanthine-guanine phosphorib...   290   6e-77
ref|NP_842632.1|  hypoxanthine-guanine phosphoribosyltransfe...   289   7e-77
ref|ZP_02525183.1|  hypoxanthine phosphoribosyltransferase [...   289   7e-77
ref|YP_001539489.1|  hypoxanthine phosphoribosyltransferase ...   289   7e-77
ref|YP_001373429.1|  hypoxanthine phosphoribosyltransferase ...   289   9e-77
ref|YP_001320712.1|  hypoxanthine phosphoribosyltransferase ...   289   9e-77
ref|YP_001256007.1|  hypoxanthine phosphoribosyltransferase ...   289   1e-76
ref|YP_001485312.1|  hypoxanthine phosphoribosyltransferase ...   288   1e-76
ref|NP_240950.1|  hypoxanthine-guanine phosphoribosyltransfe...   288   2e-76
ref|ZP_02849796.1|  hypoxanthine phosphoribosyltransferase [...   288   2e-76
ref|ZP_02263469.1|  hypoxanthine phosphoribosyltransferase [...   288   2e-76
ref|ZP_02281563.1|  hypothetical protein LmonL_01842 [Lister...   288   2e-76
ref|ZP_02618270.1|  hypoxanthine phosphoribosyltransferase [...   288   2e-76
ref|YP_001161115.1|  hypoxanthine phosphoribosyltransferase ...   288   2e-76
ref|ZP_03927309.1|  hypoxanthine phosphoribosyltransferase [...   287   3e-76
ref|ZP_00832718.1|  COG0634: Hypoxanthine-guanine phosphorib...   287   3e-76
ref|NP_829966.1|  hypoxanthine-guanine phosphoribosyltransfe...   287   3e-76
ref|ZP_03826612.1|  hypoxanthine-guanine phosphoribosyltrans...   287   4e-76
ref|ZP_01950602.1|  hypoxanthine phosphoribosyltransferase [...   287   4e-76
ref|ZP_02185480.1|  hypoxanthine-guanine phosphoribosyltrans...   287   4e-76
ref|NP_668114.2|  hypoxanthine-guanine phosphoribosyltransfe...   287   5e-76
ref|ZP_02278787.1|  hypothetical protein LmonF_02357 [Lister...   287   5e-76
ref|ZP_02044194.1|  hypothetical protein ACTODO_01053 [Actin...   287   5e-76
ref|ZP_02993965.1|  hypothetical protein CLOSPO_01067 [Clost...   287   5e-76
ref|ZP_00994139.1|  putative hypoxanthine phosphoribosyltran...   286   5e-76
ref|YP_001512894.1|  hypoxanthine phosphoribosyltransferase ...   286   5e-76
ref|ZP_03856335.1|  hypoxanthine phosphoribosyltransferase [...   286   5e-76
ref|ZP_03833725.1|  hypoxanthine-guanine phosphoribosyltrans...   286   6e-76
emb|CAG76226.1|  hypoxanthine phosphoribosyltransferase [Erw...   286   6e-76
ref|YP_051417.2|  hypoxanthine-guanine phosphoribosyltransfe...   286   6e-76
ref|YP_173609.1|  hypoxanthine-guanine phosphoribosyltransfe...   286   7e-76
ref|ZP_03910773.1|  hypoxanthine phosphoribosyltransferase [...   286   7e-76
ref|ZP_01236067.1|  hypoxanthine-guanine phosphoribosyltrans...   286   7e-76
emb|CAG21486.1|  putative hypoxanthine ribosyl transferase [...   286   8e-76
ref|YP_921672.1|  hypoxanthine phosphoribosyltransferase [No...   286   1e-75
ref|NP_406870.1|  hypoxanthine-guanine phosphoribosyltransfe...   286   1e-75
ref|NP_230235.1|  hypoxanthine-guanine phosphoribosyltransfe...   286   1e-75
ref|YP_001855782.1|  hypoxanthine phosphoribosyltransferase ...   286   1e-75
ref|YP_069264.1|  hypoxanthine-guanine phosphoribosyltransfe...   285   1e-75
ref|YP_646612.1|  hypoxanthine phosphoribosyltransferase [Ye...   285   2e-75
ref|YP_001906795.1|  Hypoxanthine phosphoribosyltransferase ...   285   2e-75
ref|ZP_03994351.1|  hypoxanthine phosphoribosyltransferase [...   285   2e-75
ref|ZP_00826602.1|  COG0634: Hypoxanthine-guanine phosphorib...   284   2e-75
ref|YP_652817.1|  hypoxanthine phosphoribosyltransferase [Ye...   284   2e-75
ref|YP_001360283.1|  hypoxanthine phosphoribosyltransferase ...   284   2e-75
ref|ZP_01160633.1|  hypoxanthine-guanine phosphoribosyltrans...   284   2e-75
dbj|BAF43658.1|  hypoxanthine ribosyl transferase [Photobact...   284   2e-75
ref|YP_520172.1|  hypothetical protein DSY3939 [Desulfitobac...   284   2e-75
ref|ZP_00821598.1|  COG0634: Hypoxanthine-guanine phosphorib...   284   2e-75
ref|ZP_02943585.1|  hypoxanthine phosphoribosyltransferase [...   284   2e-75
ref|YP_001333823.1|  hypoxanthine-guanine phosphoribosyltran...   284   3e-75
ref|ZP_03813362.1|  hypoxanthine phosphoribosyltransferase [...   284   4e-75
ref|YP_001480221.1|  hypoxanthine phosphoribosyltransferase ...   284   4e-75
ref|YP_877129.1|  hypoxanthine phosphoribosyltransferase [Cl...   284   4e-75
ref|ZP_01481302.1|  hypothetical protein VchoR_02002821 [Vib...   284   4e-75
ref|ZP_01992529.1|  hypoxanthine phosphoribosyltransferase [...   284   4e-75
ref|NP_687051.1|  hypoxanthine-guanine phosphoribosyltransfe...   283   5e-75
ref|YP_001402308.1|  hypoxanthine phosphoribosyltransferase ...   283   5e-75
ref|ZP_01189486.1|  Hypoxanthine phosphoribosyl transferase ...   283   5e-75
gb|AAB41678.1|  hypoxanthine-guanine phosphoribosyltransferase    283   6e-75
ref|NP_798894.1|  hypoxanthine-guanine phosphoribosyltransfe...   283   6e-75
ref|YP_131288.2|  hypoxanthine-guanine phosphoribosyltransfe...   283   6e-75
ref|ZP_01129459.1|  hypoxanthine phosphoribosyltransferase [...   283   6e-75
ref|NP_935562.1|  hypoxanthine-guanine phosphoribosyltransfe...   283   6e-75
ref|YP_001221583.1|  hypothetical protein CMM_0843 [Clavibac...   283   7e-75
ref|YP_001708886.1|  putative hypoxanthine phosphoribosyltra...   282   7e-75
ref|YP_062949.1|  hypoxanthine phosphoribosyltransferase [Le...   282   7e-75
ref|YP_001678694.1|  hypoxanthine phosphoribosyltransferase ...   282   8e-75
ref|YP_001586484.1|  hypothetical protein SPAB_00209 [Salmon...   282   8e-75
ref|ZP_01262549.1|  hypoxanthine-guanine phosphoribosyltrans...   282   9e-75
ref|ZP_01220020.1|  hypoxanthine-guanine phosphoribosyltrans...   282   1e-74
ref|YP_138556.1|  hypoxanthine-guanine phosphoribosyltransfe...   282   1e-74
ref|ZP_01815583.1|  hypoxanthine-guanine phosphoribosyltrans...   282   1e-74
ref|ZP_03868259.1|  hypoxanthine phosphoribosyltransferase [...   282   1e-74
ref|YP_001812555.1|  hypoxanthine phosphoribosyltransferase ...   282   1e-74
ref|ZP_02643856.1|  hypoxanthine phosphoribosyltransferase [...   282   1e-74
ref|YP_001557268.1|  hypoxanthine phosphoribosyltransferase ...   282   2e-74
ref|ZP_00831594.1|  COG0634: Hypoxanthine-guanine phosphorib...   282   2e-74
ref|YP_697159.1|  hypoxanthine phosphoribosyltransferase [Cl...   281   2e-74
ref|YP_205559.1|  hypoxanthine phosphoribosyltransferase [Vi...   281   2e-74
gb|AAX64076.1|  hypoxanthine phosphoribosyltransferase [Salm...   281   2e-74
ref|NP_563387.1|  hypoxanthine-guanine phosphoribosyltransfe...   281   2e-74
ref|YP_001439265.1|  hypothetical protein ESA_03207 [Enterob...   281   2e-74
ref|ZP_02951334.1|  hypoxanthine phosphoribosyltransferase [...   281   2e-74
ref|NP_690999.1|  hypoxanthine phosphoribosyltransferase [Oc...   281   2e-74
ref|ZP_01988476.1|  hypoxanthine phosphoribosyltransferase [...   281   2e-74
dbj|BAF43662.1|  hypoxanthine ribosyl transferase [Vibrio fi...   281   3e-74
ref|YP_807706.1|  Hypoxanthine-guanine phosphoribosyltransfe...   281   3e-74
ref|YP_396211.1|  Hypoxanthine phosphoribosyltranferase [Lac...   281   3e-74
ref|NP_720499.1|  hypoxanthine-guanine phosphoribosyltransfe...   280   4e-74
ref|ZP_01066590.1|  hypoxanthine-guanine phosphoribosyltrans...   280   4e-74
ref|YP_149518.1|  hypoxanthine-guanine phosphoribosyltransfe...   280   4e-74
ref|ZP_03958058.1|  hypoxanthine-guanine phosphoribosyltrans...   280   4e-74
ref|NP_459175.1|  hypoxanthine-guanine phosphoribosyltransfe...   280   5e-74
ref|YP_687706.1|  hypoxanthine phosphoribosyltransferase [Sh...   280   5e-74
ref|ZP_02685950.1|  hypothetical protein Salmentericaenteric...   280   5e-74
ref|YP_001843036.1|  hypoxanthine-guanine phosphoribosyltran...   280   5e-74
ref|XP_816916.1|  hypoxanthine-guanine phosphoribosyltransfe...   280   5e-74
sp|P18134|HPRT_VIBHA  Hypoxanthine phosphoribosyltransferase...   280   6e-74
ref|YP_699727.1|  hypoxanthine phosphoribosyltransferase [Cl...   279   6e-74
ref|ZP_02348869.1|  hypothetical protein Sententeri_03139 [S...   279   6e-74
ref|ZP_03845145.1|  hypoxanthine-guanine phosphoribosyltrans...   279   6e-74
ref|ZP_01825459.1|  hypoxanthine phosphoribosyltransferase [...   279   8e-74
ref|NP_780915.1|  hypoxanthine-guanine phosphoribosyltransfe...   279   8e-74
ref|YP_001175411.1|  hypoxanthine phosphoribosyltransferase ...   279   8e-74
ref|NP_454783.1|  hypoxanthine-guanine phosphoribosyltransfe...   279   8e-74
ref|ZP_02653366.1|  hypothetical protein Sententeric_20357 [...   279   9e-74
ref|ZP_03860374.1|  hypoxanthine phosphoribosyltransferase [...   279   9e-74
ref|ZP_02919438.1|  hypothetical protein STRINF_00277 [Strep...   279   1e-73
ref|NP_344565.1|  hypoxanthine-guanine phosphoribosyltransfe...   279   1e-73
pdb|1TC2|A  Chain A, Ternary Substrate Complex Of The Hypoxa...   279   1e-73
ref|ZP_02081126.1|  hypothetical protein CLOLEP_02599 [Clost...   279   1e-73
ref|YP_001571814.1|  hypothetical protein SARI_02824 [Salmon...   279   1e-73
pdb|1TC1|A  Chain A, A 1.4 Angstrom Crystal Structure For Th...   279   1e-73
ref|ZP_02832830.1|  hypothetical protein Salentericaenterica...   279   1e-73
ref|YP_001635640.1|  hypoxanthine phosphoribosyltransferase ...   279   1e-73
ref|ZP_02991800.1|  hypoxanthine phosphoribosyltransferase [...   278   1e-73
emb|CAE13159.1|  unnamed protein product [Photorhabdus lumin...   278   2e-73
ref|ZP_02340312.1|  hypothetical protein Sentent_15771 [Salm...   278   2e-73
ref|NP_928203.2|  hypoxanthine-guanine phosphoribosyltransfe...   278   2e-73
pdb|1P17|A  Chain A, Hypoxanthine Phosphoribosyltransferase ...   278   2e-73
ref|YP_002806730.1|  hypoxanthine-guanine phosphoribosyltran...   278   2e-73
gb|EEH95076.1|  hypoxanthine-guanine phosphoribosyltransfera...   278   2e-73
ref|ZP_03856512.1|  hypoxanthine phosphoribosyltransferase [...   277   2e-73
ref|ZP_01896236.1|  hypoxanthine-guanine phosphoribosyltrans...   277   3e-73
ref|ZP_03835281.1|  hypothetical protein CATC2_04748 [Citrob...   277   3e-73
ref|YP_539179.1|  hypoxanthine phosphoribosyltransferase [Es...   277   3e-73
ref|XP_813396.1|  hypoxanthine-guanine phosphoribosyltransfe...   277   3e-73
ref|ZP_02903074.1|  hypoxanthine phosphoribosyltransferase [...   277   4e-73
ref|NP_308156.2|  hypoxanthine-guanine phosphoribosyltransfe...   277   4e-73
ref|YP_309162.2|  hypoxanthine phosphoribosyltransferase [Sh...   277   4e-73
ref|ZP_00718322.1|  COG0634: Hypoxanthine-guanine phosphorib...   277   4e-73
ref|ZP_02444150.1|  hypothetical protein ANACOL_03471 [Anaer...   277   5e-73
ref|ZP_02042278.1|  hypothetical protein RUMGNA_03077 [Rumin...   277   5e-73
ref|YP_001726475.1|  hypoxanthine phosphoribosyltransferase ...   276   6e-73
ref|YP_001454762.1|  hypothetical protein CKO_03242 [Citroba...   276   6e-73
ref|YP_001916267.1|  hypoxanthine phosphoribosyltransferase ...   276   6e-73
gb|AAZ86927.1|  hypoxanthine phosphoribosyltransferase [Shig...   276   6e-73
ref|ZP_00992731.1|  hypoxanthine-guanine phosphoribosyltrans...   276   7e-73
ref|YP_074329.1|  hypoxanthine-guanine phosphoribosyltransfe...   276   7e-73
ref|ZP_04002769.1|  hypoxanthine phosphoribosyltransferase [...   276   8e-73
ref|YP_054976.1|  putative hypoxanthine phosphoribosyltransf...   276   9e-73
ref|YP_493197.1|  hypoxanthine phosphoribosyltransferase [St...   276   9e-73
ref|YP_001574409.1|  hypoxanthine phosphoribosyltransferase ...   276   1e-72
ref|YP_794711.1|  Hypoxanthine-guanine phosphoribosyltransfe...   276   1e-72
ref|ZP_00134029.2|  COG0634: Hypoxanthine-guanine phosphorib...   275   1e-72
ref|YP_001742252.1|  hypoxanthine phosphoribosyltransferase ...   275   1e-72
ref|YP_001451359.1|  hypoxanthine phosphoribosyltransferase ...   275   1e-72
ref|NP_371034.1|  hypoxanthine-guanine phosphoribosyltransfe...   275   1e-72
ref|YP_001034033.1|  Hypoxanthine guanine phosphoribosyltran...   275   2e-72
ref|YP_735273.1|  hypoxanthine phosphoribosyltransferase [Sh...   275   2e-72
ref|ZP_01704836.1|  hypoxanthine phosphoribosyltransferase [...   275   2e-72
ref|ZP_02288498.1|  hypothetical protein LmonocyFSL_01672 [L...   275   2e-72
ref|ZP_01995978.1|  hypothetical protein DORLON_01976 [Dorea...   274   2e-72
pdb|1I14|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   274   2e-72
ref|ZP_01869538.1|  hypoxanthine-guanine phosphoribosyltrans...   274   2e-72
ref|NP_928199.1|  hypoxanthine-guanine phosphoribosyltransfe...   274   2e-72
pdb|1G9S|A  Chain A, Crystal Structure Of A Complex Between ...   274   2e-72
ref|ZP_01841716.1|  hypoxanthine phosphoribosyltransferase [...   274   2e-72
ref|YP_268483.1|  hypoxanthine-guanine phosphoribosyltransfe...   274   2e-72
pdb|1I0L|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   274   2e-72
ref|YP_001053387.1|  yypoxanthine phosphoribosyltransferase ...   274   3e-72
pdb|1I0I|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   274   3e-72
ref|ZP_03894492.1|  hypoxanthine phosphoribosyltransferase [...   274   3e-72
ref|YP_001545794.1|  hypoxanthine phosphoribosyltransferase ...   274   4e-72
ref|YP_001095267.1|  hypoxanthine phosphoribosyltransferase ...   273   6e-72
ref|ZP_01965205.1|  hypothetical protein RUMOBE_02936 [Rumin...   273   6e-72
pdb|1I13|A  Chain A, Analysis Of An Invariant Aspartic Acid ...   273   6e-72
ref|YP_964712.1|  hypoxanthine phosphoribosyltransferase [Sh...   273   6e-72
ref|YP_001307245.1|  hypoxanthine phosphoribosyltransferase ...   273   7e-72
ref|YP_001672979.1|  hypoxanthine phosphoribosyltransferase ...   273   7e-72
ref|ZP_03986123.1|  hypoxanthine phosphoribosyltransferase [...   272   8e-72
ref|ZP_03939360.1|  hypoxanthine phosphoribosyltransferase [...   272   9e-72
ref|NP_349799.1|  Hypoxanthine-guanine phosphoribosyltransfe...   272   1e-71
ref|NP_719339.1|  hypoxanthine phosphoribosyltransferase [Sh...   272   1e-71
ref|ZP_02478331.1|  hypoxanthine phosphoribosyltransferase [...   272   1e-71
ref|NP_784322.1|  hypoxanthine-guanine phosphoribosyltransfe...   272   1e-71
ref|YP_254416.1|  putative hypoxanthine-guanine phosphoribos...   271   2e-71
ref|YP_001884418.1|  hypoxanthine phosphoribosyltransferase ...   271   2e-71
pdb|1R3U|A  Chain A, Crystal Structure Of Hypoxanthine-Guani...   271   2e-71
ref|ZP_03952458.1|  hypoxanthine phosphoribosyltransferase [...   270   3e-71
ref|YP_001049118.1|  hypoxanthine phosphoribosyltransferase ...   270   4e-71
ref|ZP_02431763.1|  hypothetical protein CLOSCI_01994 [Clost...   270   4e-71
ref|YP_302336.1|  putative hypoxanthine-guanine phosphoribos...   270   4e-71
ref|ZP_00874757.1|  Hypoxanthine phosphoribosyl transferase ...   270   4e-71
ref|YP_001197388.1|  Hypoxanthine-guanine phosphoribosyltran...   270   5e-71
ref|YP_001140676.1|  hypoxanthine phosphoribosyltransferase ...   270   5e-71
ref|YP_001500550.1|  hypoxanthine phosphoribosyltransferase ...   270   6e-71
ref|YP_001919611.1|  hypoxanthine phosphoribosyltransferase ...   270   6e-71
ref|NP_765828.1|  hypoxanthine-guanine phosphoribosyltransfe...   269   7e-71
ref|ZP_01788849.1|  hypoxanthine-guanine phosphoribosyltrans...   269   7e-71
ref|ZP_01967905.1|  hypothetical protein RUMTOR_01471 [Rumin...   269   7e-71
ref|ZP_02210445.1|  hypothetical protein CLOBAR_02853 [Clost...   269   7e-71
ref|YP_145914.1|  hypoxanthine-guanine phosphoribosyltransfe...   269   8e-71
ref|YP_001717770.1|  hypoxanthine phosphoribosyltransferase ...   269   8e-71
ref|NP_439311.1|  hypoxanthine-guanine phosphoribosyltransfe...   269   8e-71
ref|NP_623929.1|  Hypoxanthine-guanine phosphoribosyltransfe...   269   8e-71
ref|ZP_01074449.1|  hypoxanthine-guanine phosphoribosyltrans...   269   9e-71
ref|ZP_03942372.1|  hypoxanthine phosphoribosyltransferase [...   269   9e-71
ref|YP_645559.1|  hypoxanthine phosphoribosyltransferase [Ru...   269   1e-70
ref|ZP_01783677.1|  hypoxanthine-guanine phosphoribosyltrans...   269   1e-70
ref|ZP_00155585.2|  COG0634: Hypoxanthine-guanine phosphorib...   268   1e-70
ref|ZP_02692325.1|  hypoxanthine phosphoribosyltransferase [...   268   1e-70
gb|ABY56069.1|  hypoxanthine phosphoribosyltransferase [uncu...   268   2e-70
ref|YP_001504671.1|  hypoxanthine phosphoribosyltransferase ...   268   2e-70
ref|YP_048119.1|  hypoxanthine phosphoribosyltransferase [Ac...   268   2e-70
ref|ZP_01772665.1|  Hypothetical protein COLAER_01679 [Colli...   268   2e-70
ref|XP_822398.1|  hypoxanthine-guanine phosphoribosyltransfe...   268   2e-70
ref|ZP_03935989.1|  hypoxanthine phosphoribosyltransferase [...   268   2e-70
ref|XP_638364.1|  hypoxanthine phosphoribosyltransferase [Di...   268   2e-70
ref|XP_822405.1|  hypoxanthine-guanine phosphoribosyltransfe...   267   2e-70
ref|YP_926648.1|  Hypoxanthine phosphoribosyltransferase [Sh...   267   3e-70
ref|YP_858016.1|  hypoxanthine phosphoribosyltransferase [Ae...   267   3e-70
ref|XP_001691549.1|  hypothetical protein CHLREDRAFT_145152 ...   267   4e-70
ref|ZP_00156993.1|  COG0634: Hypoxanthine-guanine phosphorib...   267   4e-70
ref|ZP_02083316.1|  hypothetical protein CLOBOL_00837 [Clost...   267   4e-70
ref|ZP_02961601.2|  hypothetical protein PROSTU_03641 [Provi...   267   4e-70
ref|YP_001475642.1|  Hypoxanthine phosphoribosyltransferase ...   267   5e-70
ref|YP_001762172.1|  hypoxanthine phosphoribosyltransferase ...   266   6e-70
ref|YP_001715593.1|  hypoxanthine phosphoribosyltransferase ...   266   6e-70
ref|NP_387949.1|  hypoxanthine-guanine phosphoribosyltransfe...   266   6e-70
sp|Q27541|HPRT_CRIFA  Hypoxanthine-guanine phosphoribosyltra...   266   6e-70
ref|NP_245058.1|  hypoxanthine-guanine phosphoribosyltransfe...   266   8e-70
ref|YP_001124193.1|  Hypoxanthine-guanine phosphoribosyltran...   265   9e-70
ref|ZP_03891750.1|  hypoxanthine phosphoribosyltransferase [...   265   9e-70
ref|YP_248814.1|  hypoxanthine-guanine phosphoribosyltransfe...   265   9e-70
ref|ZP_01003606.1|  hypoxanthine phosphoribosyltransferase [...   265   1e-69
ref|YP_001167250.1|  hypoxanthine phosphoribosyltransferase ...   265   1e-69
gb|EEJ83385.1|  hypoxanthine phosphoribosyltransferase [Kyto...   265   1e-69
ref|YP_001664305.1|  hypoxanthine phosphoribosyltransferase ...   265   1e-69
ref|YP_001708669.1|  hypoxanthine phosphoribosyltransferase ...   265   1e-69
emb|CAO80713.1|  Hypoxanthine-guanine phosphoribosyltransfer...   265   2e-69
ref|ZP_01791303.1|  hypoxanthine-guanine phosphoribosyltrans...   265   2e-69
ref|YP_001293064.1|  hypoxanthine-guanine phosphoribosyltran...   264   2e-69
ref|ZP_03958961.1|  hypoxanthine phosphoribosyltransferase [...   264   2e-69
ref|ZP_02916961.1|  hypothetical protein BIFDEN_00221 [Bifid...   264   2e-69
ref|YP_605052.1|  hypoxanthine phosphoribosyltransferase [De...   264   2e-69
pdb|2GEB|A  Chain A, Crystal Structure Of The Thermoanaeroba...   264   2e-69
ref|ZP_02204463.1|  putative GAF sensor protein [Dehalococco...   264   3e-69
ref|YP_352844.1|  Hypoxanthine-guanine phosphoribosyltransfe...   264   3e-69
ref|ZP_01747148.1|  hypoxanthine phosphoribosyltransferase [...   264   3e-69
ref|XP_001463947.1|  HGPRT,hypoxanthine-guanine phosphoribos...   264   3e-69
ref|ZP_01173368.1|  hypoxanthine-guanine phosphoribosyltrans...   264   3e-69
ref|YP_001331506.1|  hypoxanthine phosphoribosyltransferase ...   264   3e-69
gb|EEK06649.1|  hypoxanthine phosphoribosyltransferase [Brac...   264   3e-69
ref|ZP_03823286.1|  hypoxanthine phosphoribosyltransferase [...   264   4e-69
ref|YP_561667.1|  hypoxanthine phosphoribosyltransferase [Sh...   264   4e-69
ref|ZP_03882402.1|  hypoxanthine phosphoribosyltransferase [...   264   4e-69
ref|YP_087875.1|  hypoxanthine-guanine phosphoribosyltransfe...   264   4e-69
ref|XP_001683025.1|  hypoxanthine-guanine phosphoribosyltran...   263   4e-69
ref|ZP_01742691.1|  Hypoxanthine-guanine phosphoribosyltrans...   263   5e-69
ref|YP_718674.1|  hypoxanthine phosphoribosyltransferase (HP...   263   5e-69
ref|ZP_01448574.1|  hypoxanthine phosphoribosyltransferase [...   263   5e-69
ref|ZP_02171911.1|  DNA replication and repair protein RecF ...   263   6e-69
ref|YP_001419748.1|  HprT [Bacillus amyloliquefaciens FZB42]...   263   6e-69
ref|YP_001621352.1|  hypoxanthine-guanine phosphoribosyltran...   263   6e-69
ref|NP_847264.1|  hypoxanthine-guanine phosphoribosyltransfe...   263   7e-69
Sequences not found previously or not previously below threshold:

>ref|ZP_01666882.1| hypoxanthine phosphoribosyltransferase [Thermosinus carboxydivorans
           Nor1]
 gb|EAX47240.1| hypoxanthine phosphoribosyltransferase [Thermosinus carboxydivorans
           Nor1]
          Length = 179

 Score =  306 bits (786), Expect = 6e-82,   Method: Composition-based stats.
 Identities = 68/187 (36%), Positives = 112/187 (59%), Gaps = 10/187 (5%)

Query: 8   DFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRIL 67
           +    +L +  +L  R+R + ++I+ DY+          ++++ VLRG+ +F AD+ R +
Sbjct: 3   EDIQEILLSSEQLSARIREMGRQISADYAG-------KEILMIGVLRGAVIFMADLARAI 55

Query: 68  GDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVD 127
               VP  ++F+  SSYG  T S G V +  D   D+ GKH+L++EDI+D+ LTL  ++D
Sbjct: 56  D---VPVALDFMAVSSYGASTTSSGVVRILKDLDEDVEGKHLLIVEDIIDSGLTLNYLLD 112

Query: 128 SLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
           +L+  +PASIK    ++KP  RK+    +Y    +P+ FVVGYGLDY + YR +  + IL
Sbjct: 113 NLRSRKPASIKICTLLNKPERRKVDVQVDYNGFTIPDHFVVGYGLDYAEKYRNLPFIGIL 172

Query: 188 KPSVYET 194
           KP  Y++
Sbjct: 173 KPEAYKS 179
>gb|EEJ98066.1| hypoxanthine phosphoribosyltransferase [Thermomonospora curvata DSM
           43183]
          Length = 186

 Score =  304 bits (779), Expect = 3e-81,   Method: Composition-based stats.
 Identities = 72/192 (37%), Positives = 104/192 (54%), Gaps = 10/192 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M+         SVL T+ EL  ++R +A  I  DY+          L++V VL+G+ +  
Sbjct: 1   MDDKDLGADLASVLITQEELQAKIRELAAEIDADYAG-------RDLLLVGVLKGAVMVM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R L     P  ++++  SSYG  T+S G V +  D   DI G+HVL++EDI+D+ L
Sbjct: 54  ADLARALHS---PVSMDWMAVSSYGSGTRSSGVVRILKDLDTDITGRHVLIVEDIIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  +V +L    PAS++    + KP   +      YV  D+PN FVVGYGLDY + YR 
Sbjct: 111 TLSWLVSNLASRNPASLEICALLRKPEAAQAEIDVRYVGFDIPNEFVVGYGLDYAEKYRN 170

Query: 181 VRDVVILKPSVY 192
           +  V  L P VY
Sbjct: 171 LPFVGTLAPHVY 182
>ref|NP_469596.1| fusion protein, N-terminal part similar to Bacillus subtilis YacA
           protein, C-terminal part similar to hypoxanthine-guanine
           phosphoribosyltransferase [Listeria innocua Clip11262]
 sp|Q92F56|TILS_LISIN Bifunctional protein tilS/hprT [Includes: tRNA(Ile)-lysidine
           synthase (tRNA(Ile)-lysidine synthetase)
           (tRNA(Ile)-2-lysyl-cytidine synthase);
           Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
           (HGPRTase)]
 emb|CAC95484.1| fusion protein, N-terminal part similar to B. subtilis YacA
           protein, C-terminal part similar to hypoxanthine-guanine
           phosphoribosyltransferase [Listeria innocua]
          Length = 648

 Score =  302 bits (774), Expect = 1e-80,   Method: Composition-based stats.
 Identities = 66/190 (34%), Positives = 106/190 (55%), Gaps = 10/190 (5%)

Query: 4   ACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADM 63
              ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+
Sbjct: 468 ESMHNDIQKVLISEDELQEKIRELGRELTAEYEGRNP-------LVVGVLKGATPFMTDL 520

Query: 64  VRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLR 123
           ++ +  +     ++F+  SSYG+ T S G V +  D    + G+ VL++EDI+D+  TL 
Sbjct: 521 LKRIDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLIIEDIIDSGRTLS 577

Query: 124 EVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRD 183
            +VD +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  
Sbjct: 578 YLVDLIKYRKAKSVKLVTLLDKPAGRNVAIEADYVGFVVPNEFVVGYGLDYAERYRNLPY 637

Query: 184 VVILKPSVYE 193
           + ILKP +Y 
Sbjct: 638 IGILKPEIYS 647
>ref|YP_001113711.1| hypoxanthine phosphoribosyltransferase [Desulfotomaculum reducens
           MI-1]
 gb|ABO50886.1| hypoxanthine phosphoribosyltransferase [Desulfotomaculum reducens
           MI-1]
          Length = 179

 Score =  301 bits (773), Expect = 2e-80,   Method: Composition-based stats.
 Identities = 67/189 (35%), Positives = 113/189 (59%), Gaps = 10/189 (5%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
            +     +L  E +++ R++ + Q+I  DY           +++V +L+G+ +F AD+VR
Sbjct: 1   MHPHVEKILLEENQINERIQQLGQQITQDYQG-------KDILMVGILKGAMIFLADLVR 53

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
              +  VPT  +F+  SSYG  T S G V +  D    I GKH++++EDI+DT LTL+ +
Sbjct: 54  ---NIEVPTFFDFMAVSSYGAGTVSSGVVRILKDLDKSIEGKHIIIVEDIVDTGLTLQYM 110

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
           V+++K   PAS+K    +DKP  RK+    +Y    +P+ FVVG+GLDY++ YR +  + 
Sbjct: 111 VENIKSRGPASVKVCTLLDKPDRRKVEVPIDYNGFQIPDEFVVGFGLDYNERYRNLPYIA 170

Query: 186 ILKPSVYET 194
           +LKP +Y++
Sbjct: 171 VLKPEIYQS 179
>ref|ZP_02686823.1| hypothetical protein LmonFSL_00295 [Listeria monocytogenes FSL
           J2-071]
          Length = 648

 Score =  301 bits (771), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 67/190 (35%), Positives = 106/190 (55%), Gaps = 10/190 (5%)

Query: 4   ACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADM 63
              ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+
Sbjct: 468 ESMHNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDL 520

Query: 64  VRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLR 123
           ++ +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL 
Sbjct: 521 LKRVDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLS 577

Query: 124 EVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRD 183
            +VD +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  
Sbjct: 578 YLVDLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPY 637

Query: 184 VVILKPSVYE 193
           + ILKP +Y 
Sbjct: 638 IGILKPEIYS 647
>ref|NP_463750.1| fusion protein, N-terminal part similar to B. subtilis YacA
           protein, C-terminal part similar to hypoxanthine-guanine
           phosphoribosyltransferase [Listeria monocytogenes EGD-e]
 ref|ZP_00234818.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 1/2a F6854]
 ref|ZP_01931638.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes F6900]
 ref|ZP_01936543.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes J0161]
 ref|ZP_01937061.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes J2818]
 sp|Q8YAC7|TILS_LISMO Bifunctional protein tilS/hprT [Includes: tRNA(Ile)-lysidine
           synthase (tRNA(Ile)-lysidine synthetase)
           (tRNA(Ile)-2-lysyl-cytidine synthase);
           Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
           (HGPRTase)]
 emb|CAD00746.1| fusion protein, N-terminal part similar to B. subtilis YacA
           protein, C-terminal part similar to hypoxanthine-guanine
           phosphoribosyltransferase [Listeria monocytogenes]
 gb|EAL05331.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 1/2a F6854]
 gb|EBA19187.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes J0161]
 gb|EBA27147.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes J2818]
 gb|EBA35646.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes F6900]
          Length = 648

 Score =  301 bits (771), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 67/190 (35%), Positives = 106/190 (55%), Gaps = 10/190 (5%)

Query: 4   ACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADM 63
              ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+
Sbjct: 468 ESMHNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDL 520

Query: 64  VRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLR 123
           ++ +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL 
Sbjct: 521 LKRVDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLS 577

Query: 124 EVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRD 183
            +VD +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  
Sbjct: 578 YLVDLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPY 637

Query: 184 VVILKPSVYE 193
           + ILKP +Y 
Sbjct: 638 IGILKPEIYS 647
>ref|YP_012840.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 4b F2365]
 sp|Q724J4|TILS_LISMF Bifunctional protein tilS/hprT [Includes: tRNA(Ile)-lysidine
           synthase (tRNA(Ile)-lysidine synthetase)
           (tRNA(Ile)-2-lysyl-cytidine synthase);
           Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
           (HGPRTase)]
 gb|AAT03017.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 4b F2365]
          Length = 648

 Score =  301 bits (771), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 67/190 (35%), Positives = 106/190 (55%), Gaps = 10/190 (5%)

Query: 4   ACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADM 63
              ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+
Sbjct: 468 ESMHNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDL 520

Query: 64  VRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLR 123
           ++ +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL 
Sbjct: 521 LKRVDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLS 577

Query: 124 EVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRD 183
            +VD +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  
Sbjct: 578 YLVDLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPY 637

Query: 184 VVILKPSVYE 193
           + ILKP +Y 
Sbjct: 638 IGILKPEIYS 647
>ref|ZP_02276207.1| hypothetical protein LmonFS_00952 [Listeria monocytogenes FSL
           J1-194]
          Length = 648

 Score =  301 bits (771), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 67/190 (35%), Positives = 106/190 (55%), Gaps = 10/190 (5%)

Query: 4   ACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADM 63
              ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+
Sbjct: 468 ESMHNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDL 520

Query: 64  VRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLR 123
           ++ +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL 
Sbjct: 521 LKRVDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLS 577

Query: 124 EVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRD 183
            +VD +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  
Sbjct: 578 YLVDLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPY 637

Query: 184 VVILKPSVYE 193
           + ILKP +Y 
Sbjct: 638 IGILKPEIYS 647
>ref|ZP_01926199.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes FSL N1-017]
 gb|EBA30198.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes FSL N1-017]
          Length = 648

 Score =  301 bits (771), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 67/190 (35%), Positives = 106/190 (55%), Gaps = 10/190 (5%)

Query: 4   ACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADM 63
              ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+
Sbjct: 468 ESMHNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDL 520

Query: 64  VRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLR 123
           ++ +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL 
Sbjct: 521 LKRVDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLS 577

Query: 124 EVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRD 183
            +VD +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  
Sbjct: 578 YLVDLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPY 637

Query: 184 VVILKPSVYE 193
           + ILKP +Y 
Sbjct: 638 IGILKPEIYS 647
>ref|ZP_00230936.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 4b H7858]
 ref|ZP_01942761.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes HPB2262]
 gb|AAM74001.1|AF467001_2 YacA/HprT-like protein [Listeria monocytogenes]
 gb|EAL09226.1| conserved hypothetical protein/hypoxanthine
           phosphoribosyltransferase, fusion [Listeria
           monocytogenes str. 4b H7858]
 gb|EBA38300.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes HPB2262]
          Length = 648

 Score =  300 bits (770), Expect = 3e-80,   Method: Composition-based stats.
 Identities = 67/190 (35%), Positives = 106/190 (55%), Gaps = 10/190 (5%)

Query: 4   ACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADM 63
              ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+
Sbjct: 468 ESMHNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDL 520

Query: 64  VRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLR 123
           ++ +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL 
Sbjct: 521 LKRVDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLS 577

Query: 124 EVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRD 183
            +VD +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  
Sbjct: 578 YLVDLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPY 637

Query: 184 VVILKPSVYE 193
           + ILKP +Y 
Sbjct: 638 IGILKPEIYS 647
>ref|ZP_01928838.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes FSL N3-165]
 gb|EBA33086.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes FSL N3-165]
          Length = 648

 Score =  300 bits (770), Expect = 4e-80,   Method: Composition-based stats.
 Identities = 67/190 (35%), Positives = 106/190 (55%), Gaps = 10/190 (5%)

Query: 4   ACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADM 63
              ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+
Sbjct: 468 ESMHNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDL 520

Query: 64  VRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLR 123
           ++ +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL 
Sbjct: 521 LKRVDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLS 577

Query: 124 EVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRD 183
            +VD +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  
Sbjct: 578 YLVDLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPY 637

Query: 184 VVILKPSVYE 193
           + ILKP +Y 
Sbjct: 638 IGILKPEIYS 647
>ref|ZP_01942347.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes 10403S]
 gb|EBA21850.1| tRNA(Ile)-lysidine synthetase [Listeria monocytogenes 10403S]
          Length = 648

 Score =  300 bits (769), Expect = 5e-80,   Method: Composition-based stats.
 Identities = 67/190 (35%), Positives = 106/190 (55%), Gaps = 10/190 (5%)

Query: 4   ACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADM 63
              ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+
Sbjct: 468 ESMHNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDL 520

Query: 64  VRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLR 123
           ++ +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL 
Sbjct: 521 LKRVDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLS 577

Query: 124 EVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRD 183
            +VD +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  
Sbjct: 578 YLVDLIKYRKAKSVKLVTLLDKPAGRNVEIEADYVGFVVPNEFVVGYGLDYAERYRNLPY 637

Query: 184 VVILKPSVYE 193
           + ILKP +Y 
Sbjct: 638 IGILKPEIYS 647
>ref|ZP_01514399.1| hypoxanthine phosphoribosyltransferase [Chloroflexus aggregans DSM
           9485]
 gb|EAV11938.1| hypoxanthine phosphoribosyltransferase [Chloroflexus aggregans DSM
           9485]
          Length = 180

 Score =  299 bits (766), Expect = 1e-79,   Method: Composition-based stats.
 Identities = 63/187 (33%), Positives = 102/187 (54%), Gaps = 9/187 (4%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
            +     +L +E ++  R+  +   I +DY           L++V VL+G  +F  D+ R
Sbjct: 1   MHQDIDYILISEEQIKQRVAELGAAITNDYR------AIGDLLLVGVLKGCAMFMVDLAR 54

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            +    +P  ++F+  +SYG  T+S G V +  D   DI  +HVL++EDI+D+ LTL  +
Sbjct: 55  AID---LPLAIDFIAVASYGASTESSGVVRLMKDLDTDISNRHVLIVEDIIDSGLTLAYL 111

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
              L +  PAS++    ++KP  R      +YV  D+PN FVVGYGLDY + YR +  + 
Sbjct: 112 RAQLLRRNPASLRICTLLNKPERRTADVPVDYVGFDIPNAFVVGYGLDYAERYRNLPFIG 171

Query: 186 ILKPSVY 192
           +L+P VY
Sbjct: 172 VLRPEVY 178
>ref|YP_848383.1| conserved hypothetical/hypoxanthine phosphoribosyltransferase,
           fusion protein [Listeria welshimeri serovar 6b str.
           SLCC5334]
 emb|CAK19600.1| unnamed protein product [Listeria welshimeri serovar 6b str.
           SLCC5334]
          Length = 648

 Score =  298 bits (764), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 66/190 (34%), Positives = 106/190 (55%), Gaps = 10/190 (5%)

Query: 4   ACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADM 63
              ++    VL +E EL  ++R + + +  +Y   N        +VV VL+G+  F  D+
Sbjct: 468 ESMHNDIQKVLISEDELQEKIRELGRELTTEYEGRNP-------LVVGVLKGATPFMTDL 520

Query: 64  VRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLR 123
           ++ +  +     ++F+  SSYG+ T S G V +  D    + G+ VLV+EDI+D+  TL 
Sbjct: 521 LKRVDTY---LEMDFMDVSSYGNGTVSSGEVKIIKDLNASVEGRDVLVIEDIIDSGRTLS 577

Query: 124 EVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRD 183
            +VD +K  +  S+K +  +DKP GR +   A+YV   VPN FVVGYGLDY + YR +  
Sbjct: 578 YLVDLIKYRKAKSVKLVTLLDKPAGRNVAIEADYVGFVVPNEFVVGYGLDYAERYRNLPY 637

Query: 184 VVILKPSVYE 193
           + +LKP +Y 
Sbjct: 638 IGVLKPEIYS 647
>ref|YP_359913.1| hypoxanthine phosphoribosyltransferase [Carboxydothermus
           hydrogenoformans Z-2901]
 gb|ABB13649.1| hypoxanthine phosphoribosyltransferase [Carboxydothermus
           hydrogenoformans Z-2901]
          Length = 179

 Score =  297 bits (763), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 62/188 (32%), Positives = 107/188 (56%), Gaps = 10/188 (5%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
            +     +L +E E+  +++ + Q+I+ DY+          L++V +LRG+ +F +D++R
Sbjct: 1   MHQDIAEILISEEEIRAKVKELGQQISRDYAG-------QDLLLVGILRGAMLFMSDLMR 53

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            +    +P  ++F+  SSYG  T + G V V  D    I G++VL++EDI+DT LTL  +
Sbjct: 54  EID---IPINIDFMVVSSYGSGTTTSGEVRVLKDLDRGIEGRNVLLIEDIVDTGLTLNYL 110

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
              L    P S+K    ++KP  R++    +Y    +P+ FVVGYGLDY++ YR +  + 
Sbjct: 111 TKYLANRHPKSLKVCTLLNKPSRRRVEVKVDYNGFIIPDKFVVGYGLDYNEYYRNLPYIG 170

Query: 186 ILKPSVYE 193
           +LKP +Y 
Sbjct: 171 VLKPEIYR 178
>ref|YP_002769603.1| hypoxanthine-guanine phosphoribosyltransferase [Brevibacillus
           brevis NBRC 100599]
 dbj|BAH41099.1| hypoxanthine-guanine phosphoribosyltransferase [Brevibacillus
           brevis NBRC 100599]
          Length = 179

 Score =  297 bits (763), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 66/186 (35%), Positives = 111/186 (59%), Gaps = 10/186 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               +L +E ++  ++R + + +A +Y + N        +V+ VL+G+ +F AD++R + 
Sbjct: 4   DIEKILLSEEDIAGKVRELGETLAAEYKDKNP-------LVICVLKGAVIFMADLIRHMS 56

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
              +P  ++F+  SSYG  T+S G V +  D    +  +HVLV+EDI+D+ LTL  +V+ 
Sbjct: 57  ---IPCEMDFMAVSSYGSGTESSGMVKILKDLDTSVENRHVLVVEDIMDSGLTLSRLVEL 113

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           L+  E AS+K +  ++KP  RK+  + +Y   DVP+ FVVGYGLDY + YR +  + +LK
Sbjct: 114 LRHREAASVKVVTLLNKPERRKVDISPDYKGYDVPDEFVVGYGLDYAEHYRNLPYIGVLK 173

Query: 189 PSVYET 194
           P VY  
Sbjct: 174 PEVYTK 179
>ref|ZP_03924809.1| hypoxanthine phosphoribosyltransferase [Actinomyces coleocanis DSM
           15436]
 gb|EEH64610.1| hypoxanthine phosphoribosyltransferase [Actinomyces coleocanis DSM
           15436]
          Length = 183

 Score =  297 bits (761), Expect = 5e-79,   Method: Composition-based stats.
 Identities = 68/192 (35%), Positives = 103/192 (53%), Gaps = 10/192 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M           +  TE ++  R++ +A  I  DY+          L++V VLRG+ +  
Sbjct: 1   MNAEDMGTDLQEIFLTEEQIRARIQEMAAEIDRDYAG-------KDLLLVGVLRGAIMVM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R L +   P  ++++  SSYG  TKS G V +  D   DI G+HVL++EDI+D+ L
Sbjct: 54  ADLSRALKN---PLHMDWMAVSSYGSGTKSSGVVRILKDLDTDISGRHVLIVEDIIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  + ++L    PAS++    + KP   ++    +YV  D+ N FVVGYGLDY + YR 
Sbjct: 111 TLSWLKENLSSRGPASVEIATFLRKPEAVRVDIDVKYVGFDIANEFVVGYGLDYAEKYRN 170

Query: 181 VRDVVILKPSVY 192
           +  V  L P VY
Sbjct: 171 LPFVGTLAPHVY 182
>ref|NP_627611.1| hypoxanthine phosphoribosyltransferase [Streptomyces coelicolor
           A3(2)]
 emb|CAB42758.1| putative hypoxanthine phosphoribosyltransferase [Streptomyces
           coelicolor A3(2)]
          Length = 187

 Score =  295 bits (756), Expect = 1e-78,   Method: Composition-based stats.
 Identities = 69/191 (36%), Positives = 106/191 (55%), Gaps = 10/191 (5%)

Query: 2   EPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTA 61
           +          VL T+ E+  ++  +A +I  +Y+          L++V VL+G+ +  A
Sbjct: 5   DANDMGADLEKVLITKEEIDAKLAELAAKIDAEYAG-------KDLLIVGVLKGAVMVMA 57

Query: 62  DMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALT 121
           D+ R L     P  ++++  SSYG  T+S G V +  D   DI+G+HVL++EDI+D+ LT
Sbjct: 58  DLARTLS---TPVTMDWMAVSSYGAGTQSSGVVRILKDLDTDIKGRHVLIVEDIIDSGLT 114

Query: 122 LREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREV 181
           L  ++ +L   EPAS+K    + KP   K+    E+V  D+PN FVVGYGLDY + YR +
Sbjct: 115 LSWLISNLGSREPASLKVCTLLRKPDAAKVAIDVEWVGFDIPNEFVVGYGLDYAEKYRNL 174

Query: 182 RDVVILKPSVY 192
             V  L P VY
Sbjct: 175 PFVGTLAPHVY 185
>ref|NP_825842.1| hypoxanthine phosphoribosyltransferase [Streptomyces avermitilis
           MA-4680]
 dbj|BAC72377.1| putative hypoxanthine phosphoribosyltransferase [Streptomyces
           avermitilis MA-4680]
          Length = 186

 Score =  295 bits (756), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 70/191 (36%), Positives = 107/191 (56%), Gaps = 10/191 (5%)

Query: 2   EPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTA 61
           +         SVL T+ E+  ++  +A +I  +Y+          L++V VL+G+ +  A
Sbjct: 4   DAKDMGTDLKSVLITKEEIDAKLAELAAKIDAEYAG-------KDLLIVGVLKGAVMVMA 56

Query: 62  DMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALT 121
           D+ R L     P  ++++  SSYG  T+S G V +  D   DI+GKHVL++EDI+D+ LT
Sbjct: 57  DLARALS---TPVTMDWMAVSSYGAGTQSSGVVRILKDLDTDIKGKHVLIVEDIIDSGLT 113

Query: 122 LREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREV 181
           L  ++ +L   EPAS+K    + KP   K+    E+V  D+PN FV+GYGLDY + YR +
Sbjct: 114 LSWLISNLGSREPASLKVCTLLRKPEAAKVAIDVEWVGFDIPNEFVIGYGLDYAEKYRNL 173

Query: 182 RDVVILKPSVY 192
             V  L P VY
Sbjct: 174 PFVGTLAPHVY 184
>ref|NP_814058.1| hypoxanthine-guanine phosphoribosyltransferase [Enterococcus
           faecalis V583]
 sp|Q839B2|HPRT_ENTFA Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase)
 gb|AAO80129.1| hypoxanthine-guanine phosphoribosyltransferase [Enterococcus
           faecalis V583]
          Length = 181

 Score =  294 bits (755), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 66/188 (35%), Positives = 109/188 (57%), Gaps = 10/188 (5%)

Query: 8   DFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRIL 67
                VL ++ E+  +   + +++ ++Y   N        +VV +L+G+  F AD+ R +
Sbjct: 4   KDIEKVLISKEEILAKSAELGKQLTEEYQGKNP-------LVVGILKGAVPFMADLTREI 56

Query: 68  GDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVD 127
                   ++F+  SSYG+ T S G V +  D   ++ G+H+L++EDI+D+  TL  +VD
Sbjct: 57  ---NTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRHILIVEDIIDSGRTLAYLVD 113

Query: 128 SLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
             +  + AS+K +  +DKP GR +   A+YV  DVPN FVVGYGLDY ++YR +  + +L
Sbjct: 114 LFRYRKAASVKIVTLLDKPEGRVVDIKADYVGFDVPNEFVVGYGLDYAETYRNLPYIGVL 173

Query: 188 KPSVYETW 195
           KP VYE+ 
Sbjct: 174 KPEVYESN 181
>ref|YP_001626350.1| hypoxanthine-guanine phosphoribosyltransferase [Renibacterium
           salmoninarum ATCC 33209]
 gb|ABY24936.1| hypoxanthine-guanine phosphoribosyltransferase [Renibacterium
           salmoninarum ATCC 33209]
          Length = 183

 Score =  294 bits (755), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 66/193 (34%), Positives = 107/193 (55%), Gaps = 10/193 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M+ +        VL+T+ ++ +R+  +A ++  DY+          +++V VL+G+ +  
Sbjct: 1   MDSSDVEADLKHVLYTKEQIQSRVIELAAQVDADYAG-------RDVLLVGVLKGAVMIM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R L        ++++  SSYG  T+S G V +  D   D+ GKHVL++EDI+D+ L
Sbjct: 54  ADLARALHS---HVTMDWMAVSSYGSGTQSSGVVRILKDLETDLMGKHVLIVEDIIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  +  +L    PAS++    + KP   K+    +YV  D+PN FVVGYGLD+ + YR 
Sbjct: 111 TLSWLRANLISRGPASVEICTLLRKPAAAKVEIDVKYVGYDIPNEFVVGYGLDFAEKYRN 170

Query: 181 VRDVVILKPSVYE 193
           +  V  L P VYE
Sbjct: 171 LDFVGTLAPHVYE 183
>ref|ZP_02037643.1| hypothetical protein BACCAP_03261 [Bacteroides capillosus ATCC
           29799]
 gb|EDM98927.1| hypothetical protein BACCAP_03261 [Bacteroides capillosus ATCC
           29799]
          Length = 182

 Score =  294 bits (755), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 75/184 (40%), Positives = 106/184 (57%), Gaps = 10/184 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VLF+E EL  R+  +A  I  DY+           +++SVLRGSFVF AD+ R + 
Sbjct: 5   DIERVLFSEEELDKRVSEIAAEINRDYAG-------KEPMLISVLRGSFVFMADLTRKIE 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
              VP  ++F+  SSYG  T S G+V +  D   DI GK ++V+EDILD+  TL  +++ 
Sbjct: 58  ---VPCTIDFMSVSSYGKGTTSSGQVQITKDLSDDIEGKDIIVVEDILDSGNTLSYLLEL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           L+  +PAS+K    +DKP  R      +Y    +P+ FVVGYGLDY + YR +  + ILK
Sbjct: 115 LRARKPASMKLCTLLDKPDRRVKEVHVDYSGFTIPDEFVVGYGLDYAEKYRNLPYIGILK 174

Query: 189 PSVY 192
           P VY
Sbjct: 175 PRVY 178
>ref|ZP_03922784.1| hypoxanthine phosphoribosyltransferase [Mobiluncus curtisii ATCC
           43063]
 gb|EEI89371.1| hypoxanthine phosphoribosyltransferase [Mobiluncus curtisii ATCC
           43063]
          Length = 184

 Score =  294 bits (755), Expect = 2e-78,   Method: Composition-based stats.
 Identities = 71/194 (36%), Positives = 103/194 (53%), Gaps = 10/194 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M+ A        VL TE ++  R+  +A  I  DY           L++V VLRG+ +  
Sbjct: 1   MDAADMGADMERVLLTEEQIQNRLTQMAAVIDKDYEGH-------ELLLVGVLRGAVMVM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R L     P +++++  SSYG  TKS G V +  D   DI+ +HVL++EDI+D+ L
Sbjct: 54  ADLARKLHS---PIQMDWMAVSSYGSGTKSSGVVRILKDLDTDIKDRHVLIVEDIIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  +  +L+    AS+     + KP   K      YV  D+PN FVVGYGLDY + YR 
Sbjct: 111 TLSWLEANLRTRGCASLNIATLLRKPDAAKAVVNPRYVGFDIPNEFVVGYGLDYAEHYRN 170

Query: 181 VRDVVILKPSVYET 194
           +  + +L P VYE 
Sbjct: 171 LPFIGLLAPHVYEK 184
>ref|YP_001213102.1| hypoxanthine-guanine phosphoribosyltransferase [Pelotomaculum
           thermopropionicum SI]
 dbj|BAF60733.1| hypoxanthine-guanine phosphoribosyltransferase [Pelotomaculum
           thermopropionicum SI]
          Length = 181

 Score =  294 bits (754), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 73/187 (39%), Positives = 109/187 (58%), Gaps = 10/187 (5%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
            +     +LFTE E+  R+  + + I+ DY+          L+VV +L+G+ +F AD+VR
Sbjct: 1   MHPDGERILFTEEEIRARVAEMGREISRDYAG-------RELLVVGILKGAMIFLADLVR 53

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            +    VP   +F+  SSYG  TKS G V +  D    I G+HVL++EDI+DT LTL  +
Sbjct: 54  SIT---VPAFFDFIAVSSYGTSTKSSGAVRILKDLDRGIEGRHVLIVEDIVDTGLTLNYL 110

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
           VD+L    PAS+K    +DKP  R+ P    Y    +P+ FVVGYGLDY++ YR +  ++
Sbjct: 111 VDNLTARGPASLKVCTLLDKPSRRQKPVEIHYNGFTIPDEFVVGYGLDYNECYRNLPYIM 170

Query: 186 ILKPSVY 192
           +L P V+
Sbjct: 171 VLSPRVF 177
>ref|ZP_02091227.1| hypothetical protein FAEPRAM212_01498 [Faecalibacterium prausnitzii
           M21/2]
 gb|EDP21677.1| hypothetical protein FAEPRAM212_01498 [Faecalibacterium prausnitzii
           M21/2]
          Length = 180

 Score =  294 bits (753), Expect = 3e-78,   Method: Composition-based stats.
 Identities = 76/190 (40%), Positives = 110/190 (57%), Gaps = 11/190 (5%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
            +D   +VL +E +L  ++  +  +I+ DY+  N       LV+VS+L+GS VF AD++R
Sbjct: 1   MHDDIKTVLVSEEQLKAKVAELGAQISRDYAGKN-------LVLVSILKGSVVFMADLMR 53

Query: 66  ILGDFGVPTRVEFLRASSYGHD-TKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLRE 124
            +    +P  ++F+  SSYG   T + G V +  D   D+ GK VL++EDILDT +TL  
Sbjct: 54  AVS---IPCNIDFMVVSSYGGSNTTTSGLVKIIKDLDGDLSGKDVLIVEDILDTGVTLSN 110

Query: 125 VVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDV 184
           +V  LK   P S+K    +DKP  RK     +Y    VP+ FVVGYGLDYD+ YR +  V
Sbjct: 111 LVPMLKMRNPNSVKICTILDKPSRRKADIQPDYEGFQVPDEFVVGYGLDYDEKYRNLPYV 170

Query: 185 VILKPSVYET 194
            +LKP VY  
Sbjct: 171 GVLKPEVYTK 180
>ref|ZP_02330217.1| hypothetical protein Plarl_21636 [Paenibacillus larvae subsp.
           larvae BRL-230010]
          Length = 188

 Score =  294 bits (753), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 60/186 (32%), Positives = 107/186 (57%), Gaps = 10/186 (5%)

Query: 8   DFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRIL 67
           +    V FTE ++  +++ +  ++++D+   N        +V+ VL+G+F+F AD+V+ +
Sbjct: 12  NDIQEVFFTEEQIQEKIKELGGKLSEDFKGRNP-------LVICVLKGAFIFMADLVKQM 64

Query: 68  GDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVD 127
               VP  ++F+  SSYG  TKS G V +  D    + G+ +L++EDI+D+ LTL  ++D
Sbjct: 65  T---VPLEIDFMAVSSYGASTKSSGVVKIIKDLDTSVEGRDILIVEDIIDSGLTLSYLID 121

Query: 128 SLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
            LK+    S+  +   +KP  R +    +YV   + + F+VGYGLDY + YR +  + +L
Sbjct: 122 VLKRRNAKSVSIVTLFNKPARRTVDLEPDYVGFKIDDAFIVGYGLDYAEKYRNLPFIGVL 181

Query: 188 KPSVYE 193
           KP +Y 
Sbjct: 182 KPEIYS 187
>ref|YP_644942.1| hypoxanthine phosphoribosyltransferase [Rubrobacter xylanophilus
           DSM 9941]
 gb|ABG05130.1| hypoxanthine phosphoribosyltransferase [Rubrobacter xylanophilus
           DSM 9941]
          Length = 189

 Score =  293 bits (752), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 67/191 (35%), Positives = 106/191 (55%), Gaps = 9/191 (4%)

Query: 2   EPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTA 61
           E +        VL    E+  +++ + ++I  DY           L++V VLRG+ +   
Sbjct: 3   EMSSMMPDVQEVLIPSEEIQQKVKDLGEQITRDYREH------RRLLLVGVLRGAVIVMG 56

Query: 62  DMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALT 121
           D++R +    +P  ++F+  SSYG  T S G V +  D   DI G+HVL++EDI+DT LT
Sbjct: 57  DLMRRID---LPCEIDFMEVSSYGAGTTSSGVVRILKDLEEDISGRHVLIVEDIIDTGLT 113

Query: 122 LREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREV 181
           L  +  SL   +PAS++    + KP  R++    +Y+  ++P+ FVVGYGLDY   YR +
Sbjct: 114 LSYLRRSLLARKPASLEICALLSKPARRRVELDVKYLGFEIPDEFVVGYGLDYAGCYRNL 173

Query: 182 RDVVILKPSVY 192
            D+ ILKP V+
Sbjct: 174 PDICILKPEVF 184
>ref|YP_001274703.1| hypoxanthine phosphoribosyltransferase [Roseiflexus sp. RS-1]
 gb|ABQ88753.1| hypoxanthine phosphoribosyltransferase [Roseiflexus sp. RS-1]
          Length = 682

 Score =  293 bits (752), Expect = 5e-78,   Method: Composition-based stats.
 Identities = 63/191 (32%), Positives = 101/191 (52%), Gaps = 9/191 (4%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
            +D    +L T  ++  R+R +  +I  DY       L   L      +G  +F  D+ R
Sbjct: 501 MHDDMAKILLTAEQIQERVRALGAQITTDYRPLGDLLLVGVL------KGCAMFMVDLAR 554

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            +    +P  ++F+  SSYG  T+S G V +  D   DI G+HVL++EDI+D+ LTL  +
Sbjct: 555 AID---LPLGMDFIATSSYGKTTESSGVVRMLKDLDTDIAGRHVLIVEDIIDSGLTLAYL 611

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
              L +  PAS++    ++KP  R+     +Y+  D+PN FVVGYGLD+D+ YR +  + 
Sbjct: 612 RGHLLRRNPASLRICALLNKPERRRADIPIDYLGFDIPNEFVVGYGLDFDEKYRNLPYIG 671

Query: 186 ILKPSVYETWG 196
           +L   +Y T  
Sbjct: 672 VLHERIYHTTA 682
>ref|ZP_00603444.1| Hypoxanthine phosphoribosyl transferase [Enterococcus faecium DO]
 gb|EAN10267.1| Hypoxanthine phosphoribosyl transferase [Enterococcus faecium DO]
          Length = 181

 Score =  292 bits (750), Expect = 8e-78,   Method: Composition-based stats.
 Identities = 67/188 (35%), Positives = 110/188 (58%), Gaps = 10/188 (5%)

Query: 8   DFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRIL 67
                +L ++ E+  R + + + + + Y N N        +VV VL+G+  F AD+VR +
Sbjct: 4   KDIERILISQEEIQVRCKELGKELTEIYQNTNP-------LVVGVLKGAVPFMADIVRSI 56

Query: 68  GDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVD 127
             +     ++F+  SSYG+ T S G V +  D   ++ G+ +L++EDI+D+  TL  +VD
Sbjct: 57  DTY---LELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDIIDSGRTLAYLVD 113

Query: 128 SLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
             K  +  S+K +  +DKP GR +   A+YV  +VPN FVVGYGLDY ++YR +  + +L
Sbjct: 114 LFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDYAEAYRNLPYIGVL 173

Query: 188 KPSVYETW 195
           KPSVY++ 
Sbjct: 174 KPSVYQSN 181
>ref|YP_290952.1| hypoxanthine phosphoribosyl transferase [Thermobifida fusca YX]
 gb|AAZ56929.1| hypoxanthine phosphoribosyltransferase [Thermobifida fusca YX]
          Length = 184

 Score =  292 bits (749), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 68/193 (35%), Positives = 106/193 (54%), Gaps = 10/193 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M+          +L TE ++ TR R +A  I  DY+          L++V VL+G+ +  
Sbjct: 1   MDAKDMGSALDKILVTEEQIRTRTRELAAEIDADYAG-------KDLLLVGVLKGAVMVM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R L     P  ++++  SSYG  T S G V +  D   DI+G++VL++ED++D+ L
Sbjct: 54  ADLARELHH---PCEMDWMAVSSYGAGTTSSGVVRILKDLDTDIQGRNVLIVEDVIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  +V +LK   PAS++    + KP    +    +YV  D+PN F+VGYGLDY + YR 
Sbjct: 111 TLSWLVGNLKSRHPASVEICTMVRKPMAFNVDLDVKYVGFDLPNEFIVGYGLDYAEKYRN 170

Query: 181 VRDVVILKPSVYE 193
           +  +  L P VY+
Sbjct: 171 LPFIATLAPHVYD 183
>ref|YP_001825599.1| putative hypoxanthine phosphoribosyltransferase [Streptomyces
           griseus subsp. griseus NBRC 13350]
 dbj|BAG20916.1| putative hypoxanthine phosphoribosyltransferase [Streptomyces
           griseus subsp. griseus NBRC 13350]
          Length = 184

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 69/192 (35%), Positives = 107/192 (55%), Gaps = 10/192 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M          SVL T+ E+  ++  +A +I  +Y+          L++V VL+G+ +  
Sbjct: 1   MNEKDMGTDLQSVLLTKEEIDAKLVELAAKIDAEYAG-------KDLLIVGVLKGAVMVM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R L     P  ++++  SSYG  T+S G V +  D   DI+GKHVL++EDI+D+ L
Sbjct: 54  ADLARALS---TPVTMDWMAVSSYGAGTQSSGVVRILKDLDTDIKGKHVLIVEDIIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  ++ +L   EPAS++    + KP   K+    +++  D+PN FVVGYGLDY + YR 
Sbjct: 111 TLSWLLSNLGSREPASLEVCTLLRKPDAAKVAIDVKWIGFDIPNEFVVGYGLDYAEKYRN 170

Query: 181 VRDVVILKPSVY 192
           +  V  L P VY
Sbjct: 171 LPFVGTLAPHVY 182
>ref|ZP_03982713.1| Hypoxanthine phosphoribosyltransferase [Enterococcus faecium
           TX1330]
 gb|EEI59165.1| Hypoxanthine phosphoribosyltransferase [Enterococcus faecium
           TX1330]
          Length = 181

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 66/188 (35%), Positives = 110/188 (58%), Gaps = 10/188 (5%)

Query: 8   DFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRIL 67
                +L ++ E+  R + + + + + Y N N        +VV VL+G+  F AD+VR +
Sbjct: 4   KDIERILISQEEIQVRCKELGKELTEIYQNTNP-------LVVGVLKGAVPFMADIVRSI 56

Query: 68  GDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVD 127
             +     ++F+  SSYG+ T S G V +  D   ++ G+ +L++EDI+D+  TL  +VD
Sbjct: 57  DTY---LELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDIIDSGRTLAYLVD 113

Query: 128 SLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
             K  +  S+K +  +DKP GR +   A+YV  +VPN FVVGYGLDY ++YR +  + +L
Sbjct: 114 LFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDYAEAYRNLPYIGVL 173

Query: 188 KPSVYETW 195
           KP+VY++ 
Sbjct: 174 KPTVYQSN 181
>ref|YP_001695855.1| Hypoxanthine-guanine phosphoribosyltransferase [Lysinibacillus
           sphaericus C3-41]
 gb|ACA37725.1| Hypoxanthine-guanine phosphoribosyltransferase [Lysinibacillus
           sphaericus C3-41]
          Length = 180

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 67/187 (35%), Positives = 106/187 (56%), Gaps = 10/187 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
            +    V+ TE +L  R+  +  ++ ++Y +          + V VL+G+  F  D+++ 
Sbjct: 3   QNDIEKVMITEEQLQERIADLGAQLTEEYKDAFP-------LAVGVLKGAMPFMTDLMKR 55

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
              F     ++F+  SSYG+ T S G V +  D    + G+ VL++EDI+D+ LTL  +V
Sbjct: 56  FDSF---IELDFMDVSSYGNATVSSGEVKILKDLNTSVEGRDVLIIEDIIDSGLTLSYLV 112

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D  K  +  SIK +  +DKP GRK+  +A+YV  +VP+ FVVGYGLDY + YR +  + I
Sbjct: 113 DLFKYRKAKSIKIVTLLDKPSGRKVNLSADYVGFEVPDGFVVGYGLDYAEKYRNLPYIGI 172

Query: 187 LKPSVYE 193
           LKP VY 
Sbjct: 173 LKPEVYS 179
>ref|ZP_02836636.1| hypoxanthine phosphoribosyltransferase [Arthrobacter
           chlorophenolicus A6]
 gb|EDS63445.1| hypoxanthine phosphoribosyltransferase [Arthrobacter
           chlorophenolicus A6]
          Length = 183

 Score =  292 bits (748), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 68/193 (35%), Positives = 103/193 (53%), Gaps = 10/193 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M+          VL+T+ ++  R+  +A +I  DY           L++V VL+G+ +  
Sbjct: 1   MDSNDVQADLKHVLYTKEQIQQRITELAAQIDKDYEG-------RELLIVGVLKGAVMVM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R L        ++++  SSYG  T+S G V +  D   D+ GK VL++EDI+D+ L
Sbjct: 54  ADLARALHS---HVSMDWMAVSSYGSGTQSSGVVRILKDLDTDLMGKDVLIVEDIIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  +  +L+    AS++   A  KP   K+    +YV  D+PN FVVGYGLDY + YR 
Sbjct: 111 TLSWLKTNLESRGTASVEICTAFRKPTAAKVQIDVKYVGYDIPNEFVVGYGLDYAEKYRN 170

Query: 181 VRDVVILKPSVYE 193
           +  V  L P VYE
Sbjct: 171 LDFVGTLAPHVYE 183
>ref|YP_001430999.1| hypoxanthine phosphoribosyltransferase [Roseiflexus castenholzii
           DSM 13941]
 gb|ABU56981.1| hypoxanthine phosphoribosyltransferase [Roseiflexus castenholzii
           DSM 13941]
          Length = 676

 Score =  291 bits (747), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 61/191 (31%), Positives = 101/191 (52%), Gaps = 9/191 (4%)

Query: 6   KYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVR 65
            +D    +L T  ++  R+R +  +I  DY       L   L      +G  +F  D+ R
Sbjct: 495 MHDDMAKILITAGQIQERVRALGAQITADYRPLGDLLLVGVL------KGCAMFMVDLAR 548

Query: 66  ILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREV 125
            +    +P  ++F+  SSYG  T+S G V +  D   DI G+HV+++EDI+D+ LTL  +
Sbjct: 549 AID---MPLAMDFIATSSYGKTTESSGVVRMLKDLDTDIAGRHVVIVEDIIDSGLTLAYL 605

Query: 126 VDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVV 185
              L +  PAS++    ++KP  R+     +Y+  D+PN FVVGYGLD+D+ YR +  + 
Sbjct: 606 RGHLLRRNPASLRICALLNKPSRRRADIPIDYLGFDIPNEFVVGYGLDFDEKYRNLPYIG 665

Query: 186 ILKPSVYETWG 196
           +L   +Y +  
Sbjct: 666 VLHERIYHSTA 676
>ref|ZP_02581448.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus B4264]
          Length = 180

 Score =  291 bits (747), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 69/185 (37%), Positives = 106/185 (57%), Gaps = 10/185 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VL +E ++  ++R +   IA+DY N          + + VL+G+  F AD+++   
Sbjct: 5   DIEKVLISEEQIQEKVRELGAIIAEDYKNTVP-------LAIGVLKGAMPFMADLLKRTD 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
            +     ++F+  SSYGH T S G V +  D    + G+ +L++EDI+D+ LTL  +VD 
Sbjct: 58  TY---LEMDFMAVSSYGHSTVSTGEVKILKDLDTSVEGRDILIVEDIIDSGLTLSYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            K  +  S+K +  +DKP GRK+   A+YV   VP+ FVVGYGLDY + YR +  V +LK
Sbjct: 115 FKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVLK 174

Query: 189 PSVYE 193
           PSVY 
Sbjct: 175 PSVYS 179
>ref|ZP_04009409.1| hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus
           salivarius ATCC 11741]
 gb|EEJ74172.1| hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus
           salivarius ATCC 11741]
          Length = 179

 Score =  291 bits (747), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 65/186 (34%), Positives = 103/186 (55%), Gaps = 10/186 (5%)

Query: 8   DFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRIL 67
           +    VL+++ ++    + + ++I  D+   N        +VV VL+G+ +FT D++R +
Sbjct: 3   NDIKEVLYSKEQIAEVTKRLGKQITKDFEGKNP-------LVVCVLKGAVMFTTDIIREI 55

Query: 68  GDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVD 127
             +     ++F+  SSYG  T+S G V +  D    + G+ VL++EDI+DT  TL+ +V+
Sbjct: 56  DTY---LELDFMDVSSYGEGTESSGEVKIIKDLDTSVTGRDVLIVEDIIDTGRTLQRLVE 112

Query: 128 SLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
             K     S+K    +DKP  R      +YV  +VPN FVVGYGLD+   YR +  V IL
Sbjct: 113 LFKHRNAKSVKICTLLDKPERRVEGVKPDYVGFEVPNEFVVGYGLDFAGRYRNLGYVGIL 172

Query: 188 KPSVYE 193
           KP VYE
Sbjct: 173 KPEVYE 178
>ref|ZP_00741717.1| Hypoxanthine-guanine phosphoribosyltransferase [Bacillus
           thuringiensis serovar israelensis ATCC 35646]
 ref|ZP_02587714.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus G9842]
 gb|EAO54011.1| Hypoxanthine-guanine phosphoribosyltransferase [Bacillus
           thuringiensis serovar israelensis ATCC 35646]
          Length = 180

 Score =  291 bits (746), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 69/185 (37%), Positives = 106/185 (57%), Gaps = 10/185 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VL +E ++  ++R +   IA+DY N          + + VL+G+  F AD+++   
Sbjct: 5   DIEKVLISEEQIQEKVRELGAVIAEDYKNTVP-------LAIGVLKGAMPFMADLLKRTD 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
            +     ++F+  SSYGH T S G V +  D    + G+ +L++EDI+D+ LTL  +VD 
Sbjct: 58  TY---LEMDFMAVSSYGHSTVSTGEVKILKDLDTSVEGRDILIVEDIIDSGLTLSYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            K  +  S+K +  +DKP GRK+   A+YV   VP+ FVVGYGLDY + YR +  V +LK
Sbjct: 115 FKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVLK 174

Query: 189 PSVYE 193
           PSVY 
Sbjct: 175 PSVYS 179
>ref|YP_945962.1| hypoxanthine phosphoribosyltransferase [Arthrobacter aurescens TC1]
 gb|ABM06301.1| hypoxanthine phosphoribosyltransferase [Arthrobacter aurescens TC1]
          Length = 183

 Score =  291 bits (746), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 68/193 (35%), Positives = 104/193 (53%), Gaps = 10/193 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M+          VL+T+ ++ TR+  +A +I  DY           +++V VL+G+ +  
Sbjct: 1   MDSNDVQADLKHVLYTKEQIQTRIAELAAQIDKDYEG-------RDILIVGVLKGAVMVM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R L        ++++  SSYG  T+S G V +  D   D+ GK VL++EDI+D+ L
Sbjct: 54  ADLARALHS---HVSMDWMAVSSYGSGTQSSGVVRILKDLDTDLMGKDVLIVEDIIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  +  +L+    AS++   A  KP   K+    +YV  D+PN FVVGYGLDY + YR 
Sbjct: 111 TLSWLKSNLESRGTASVEICTAFRKPTAAKVEIDVKYVGYDIPNEFVVGYGLDYAEKYRN 170

Query: 181 VRDVVILKPSVYE 193
           +  V  L P VYE
Sbjct: 171 LDFVGTLAPHVYE 183
>ref|YP_001642956.1| hypoxanthine phosphoribosyltransferase [Bacillus weihenstephanensis
           KBAB4]
 gb|ABY41328.1| hypoxanthine phosphoribosyltransferase [Bacillus weihenstephanensis
           KBAB4]
          Length = 180

 Score =  290 bits (744), Expect = 3e-77,   Method: Composition-based stats.
 Identities = 68/185 (36%), Positives = 105/185 (56%), Gaps = 10/185 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VL +E ++  ++  +   IA+DY N          + + VL+G+  F AD+++   
Sbjct: 5   DIEKVLISEEQIQEKVHELGAVIAEDYKNTVP-------LAIGVLKGAMPFMADLLKRTD 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
            +     ++F+  SSYGH T S G V +  D    + G+ +L++EDI+D+ LTL  +VD 
Sbjct: 58  TY---LEMDFMAVSSYGHSTVSTGEVKILKDLDTSVEGRDILIVEDIIDSGLTLSYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            K  +  S+K +  +DKP GRK+   A+YV   VP+ FVVGYGLDY + YR +  V +LK
Sbjct: 115 FKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVLK 174

Query: 189 PSVYE 193
           PSVY 
Sbjct: 175 PSVYS 179
>ref|YP_536242.1| Hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus
           salivarius UCC118]
 gb|ABE00159.1| Hypoxanthine-guanine phosphoribosyltransferase [Lactobacillus
           salivarius UCC118]
          Length = 179

 Score =  290 bits (744), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 65/186 (34%), Positives = 103/186 (55%), Gaps = 10/186 (5%)

Query: 8   DFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRIL 67
           +    VL+++ ++    + + ++I  D+   N        +VV VL+G+ +FT D++R +
Sbjct: 3   NDIKEVLYSKEQIAEVTKKLGKQITKDFEGKNP-------LVVCVLKGAVMFTTDIIREI 55

Query: 68  GDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVD 127
             +     ++F+  SSYG  T+S G V +  D    + G+ VL++EDI+DT  TL+ +V+
Sbjct: 56  DTY---LELDFMDVSSYGEGTESSGEVKIIKDLDTSVTGRDVLIVEDIIDTGRTLQRLVE 112

Query: 128 SLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
             K     S+K    +DKP  R      +YV  +VPN FVVGYGLD+   YR +  V IL
Sbjct: 113 LFKHRNAKSVKICTLLDKPERRVEGVKPDYVGFEVPNEFVVGYGLDFAGRYRNLGYVGIL 172

Query: 188 KPSVYE 193
           KP VYE
Sbjct: 173 KPEVYE 178
>ref|ZP_01725398.1| hypoxanthine-guanine phosphoribosyltransferase [Bacillus sp.
           B14905]
 gb|EAZ84090.1| hypoxanthine-guanine phosphoribosyltransferase [Bacillus sp.
           B14905]
          Length = 180

 Score =  290 bits (744), Expect = 4e-77,   Method: Composition-based stats.
 Identities = 67/187 (35%), Positives = 105/187 (56%), Gaps = 10/187 (5%)

Query: 7   YDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRI 66
            +    V+ TE +L  R+  +  ++ ++Y +          + V VL+G+  F  D+++ 
Sbjct: 3   QNDIEKVMITEEQLQERIADLGAQLTEEYKDAFP-------LAVGVLKGAMPFMTDLMKR 55

Query: 67  LGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVV 126
              F     ++F+  SSYG+ T S G V +  D    + G+ VL++EDI+D+ LTL  +V
Sbjct: 56  FDSF---IELDFMDVSSYGNATVSSGEVKILKDLNTSVEGRDVLIIEDIIDSGLTLSYLV 112

Query: 127 DSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVI 186
           D  K  +  SIK +  +DKP GRK+  +A+YV   VP+ FVVGYGLDY + YR +  + I
Sbjct: 113 DLFKYRKAKSIKIVTLLDKPSGRKVNLSADYVGFKVPDGFVVGYGLDYAEKYRNLPYIGI 172

Query: 187 LKPSVYE 193
           LKP VY 
Sbjct: 173 LKPEVYS 179
>ref|YP_829651.1| hypoxanthine phosphoribosyltransferase [Arthrobacter sp. FB24]
 gb|ABK01551.1| hypoxanthine phosphoribosyltransferase [Arthrobacter sp. FB24]
          Length = 183

 Score =  290 bits (743), Expect = 5e-77,   Method: Composition-based stats.
 Identities = 68/193 (35%), Positives = 103/193 (53%), Gaps = 10/193 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M+          VL+T+ ++  R+  +A +I  DY           L++V VL+G+ +  
Sbjct: 1   MDSNDVQADLKHVLYTKDQIQQRITELAAQIDKDYEG-------RELLIVGVLKGAVMVM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R L        ++++  SSYG  T+S G V +  D   D+ GK VL++EDI+D+ L
Sbjct: 54  ADLARALHS---HVSMDWMAVSSYGSGTQSSGVVRILKDLDTDLMGKDVLIVEDIIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  +  +L+    AS++   A  KP   K+    +YV  D+PN FVVGYGLDY + YR 
Sbjct: 111 TLSWLKTNLESRGTASVEICTAFRKPTAAKVQIDVKYVGYDIPNEFVVGYGLDYAEKYRN 170

Query: 181 VRDVVILKPSVYE 193
           +  V  L P VYE
Sbjct: 171 LDFVGTLAPHVYE 183
>ref|ZP_00379834.1| COG0634: Hypoxanthine-guanine phosphoribosyltransferase
           [Brevibacterium linens BL2]
          Length = 183

 Score =  290 bits (743), Expect = 6e-77,   Method: Composition-based stats.
 Identities = 64/193 (33%), Positives = 103/193 (53%), Gaps = 10/193 (5%)

Query: 1   MEPACKYDFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFT 60
           M+     +    VL +E ++  R+  +A  I +DY           +++V VL+G+ +  
Sbjct: 1   MDINDLGNDIEKVLVSEEQIAARLVELATAIDEDYKG-------KDILLVGVLKGAVMVM 53

Query: 61  ADMVRILGDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTAL 120
           AD+ R +     P  ++++  SSYG  TKS G V +  D   D+  +HVL++EDI+D+ L
Sbjct: 54  ADLARAIHS---PVTMDWMAVSSYGSGTKSSGVVRILKDLDTDLSDRHVLIVEDIIDSGL 110

Query: 121 TLREVVDSLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYRE 180
           TL  +V +L+    A+++    + KP   K+    +Y+  DVPN FV+GYGLDY + YR 
Sbjct: 111 TLSWLVQNLRSRGAATVEICTMLRKPEAVKVDIDVKYIGFDVPNEFVIGYGLDYAEKYRN 170

Query: 181 VRDVVILKPSVYE 193
           V  V  L   VY 
Sbjct: 171 VPFVATLAQHVYS 183
>ref|NP_842632.1| hypoxanthine-guanine phosphoribosyltransferase [Bacillus anthracis
           str. Ames]
 ref|NP_976390.1| hypoxanthine-guanine phosphoribosyltransferase [Bacillus cereus
           ATCC 10987]
 ref|YP_016666.1| hypoxanthine-guanine phosphoribosyltransferase [Bacillus anthracis
           str. 'Ames Ancestor']
 ref|ZP_00240842.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus G9241]
 ref|YP_026350.1| hypoxanthine-guanine phosphoribosyltransferase [Bacillus anthracis
           str. Sterne]
 ref|YP_034417.1| hypoxanthine-guanine phosphoribosyltransferase [Bacillus
           thuringiensis serovar konkukian str. 97-27]
 ref|YP_081676.1| hypoxanthine-guanine phosphoribosyltransferase [Bacillus cereus
           E33L]
 ref|ZP_00390484.1| COG0634: Hypoxanthine-guanine phosphoribosyltransferase [Bacillus
           anthracis str. A2012]
 ref|YP_892986.1| hypoxanthine phosphoribosyltransferase [Bacillus thuringiensis str.
           Al Hakam]
 ref|ZP_02255976.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus AH187]
 ref|ZP_02543137.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus W]
 ref|ZP_02592819.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus NVH0597-99]
 ref|ZP_02598797.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus H3081.97]
 ref|ZP_02605417.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus 03BB108]
 ref|ZP_02611234.1| hypoxanthine phosphoribosyltransferase [Bacillus anthracis
           Tsiankovskii-I]
 gb|AAP24118.1| hypoxanthine phosphoribosyltransferase [Bacillus anthracis str.
           Ames]
 gb|AAS38998.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus ATCC 10987]
 gb|AAT29141.1| hypoxanthine phosphoribosyltransferase [Bacillus anthracis str.
           'Ames Ancestor']
 gb|EAL11529.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus G9241]
 gb|AAT52401.1| hypoxanthine phosphoribosyltransferase [Bacillus anthracis str.
           Sterne]
 gb|AAT61527.1| hypoxanthine phosphoribosyltransferase (hypoxanthine-guanine
           phosphoribosyltransferase) [Bacillus thuringiensis
           serovar konkukian str. 97-27]
 gb|AAU20171.1| hypoxanthine phosphoribosyltransferase (hypoxanthine-guanine
           phosphoribosyltransferase) [Bacillus cereus E33L]
 gb|ABK83479.1| hypoxanthine phosphoribosyltransferase [Bacillus thuringiensis str.
           Al Hakam]
          Length = 180

 Score =  289 bits (742), Expect = 7e-77,   Method: Composition-based stats.
 Identities = 68/185 (36%), Positives = 105/185 (56%), Gaps = 10/185 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VL +E ++  ++  +   IA+DY N          + + VL+G+  F AD+++   
Sbjct: 5   DIEKVLISEEQIQEKVLELGAIIAEDYKNTVP-------LAIGVLKGAMPFMADLLKRTD 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
            +     ++F+  SSYGH T S G V +  D    + G+ +L++EDI+D+ LTL  +VD 
Sbjct: 58  TY---LEMDFMAVSSYGHSTVSTGEVKILKDLDTSVEGRDILIVEDIIDSGLTLSYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            K  +  S+K +  +DKP GRK+   A+YV   VP+ FVVGYGLDY + YR +  V +LK
Sbjct: 115 FKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVLK 174

Query: 189 PSVYE 193
           PSVY 
Sbjct: 175 PSVYS 179
>ref|ZP_02525183.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus AH1134]
          Length = 180

 Score =  289 bits (742), Expect = 7e-77,   Method: Composition-based stats.
 Identities = 68/185 (36%), Positives = 106/185 (57%), Gaps = 10/185 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VL +E ++  ++R +   +A+DY N          + + VL+G+  F AD+++   
Sbjct: 5   DIEKVLISEEQIQEKVRELGAIVAEDYKNTVP-------LAIGVLKGAMPFMADLLKRTD 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
            +     ++F+  SSYGH T S G V +  D    + G+ +L++EDI+D+ LTL  +VD 
Sbjct: 58  TY---LEMDFMAVSSYGHSTVSTGEVKILKDLDTSVEGRDILIVEDIIDSGLTLSYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            K  +  S+K +  +DKP GRK+   A+YV   VP+ FVVGYGLDY + YR +  V +LK
Sbjct: 115 FKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVLK 174

Query: 189 PSVYE 193
           PSVY 
Sbjct: 175 PSVYS 179
>ref|YP_001539489.1| hypoxanthine phosphoribosyltransferase [Salinispora arenicola
           CNS-205]
 gb|ABW00499.1| hypoxanthine phosphoribosyltransferase [Salinispora arenicola
           CNS-205]
          Length = 190

 Score =  289 bits (742), Expect = 7e-77,   Method: Composition-based stats.
 Identities = 71/186 (38%), Positives = 112/186 (60%), Gaps = 5/186 (2%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               V+ +EA++  +   +A++++ DY++     +E+ L++V VL+G+ +F AD  R LG
Sbjct: 10  DIDHVIISEAQIREKTAELAKQVSADYAD-----VEDGLLLVCVLKGAVMFMADFARALG 64

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
             G P  +EF+  SSYG  T S G V +  D   DI G+HV+V+EDI+D+ LTL  ++  
Sbjct: 65  RQGPPAELEFMAISSYGQGTTSSGVVRILKDLDRDIAGRHVVVVEDIVDSGLTLSWLLRY 124

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           L+    AS++ +    KP   K+P   +YV  D+P  FVVGYGLD+ + YRE+  V +L+
Sbjct: 125 LESRSAASVEVVALFRKPEAVKVPVEVKYVGFDIPTEFVVGYGLDFGERYRELPYVGVLR 184

Query: 189 PSVYET 194
           P VY  
Sbjct: 185 PEVYAR 190
>ref|YP_001373429.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus subsp.
           cytotoxis NVH 391-98]
 gb|ABS20434.1| hypoxanthine phosphoribosyltransferase [Bacillus cereus subsp.
           cytotoxis NVH 391-98]
          Length = 180

 Score =  289 bits (741), Expect = 9e-77,   Method: Composition-based stats.
 Identities = 67/185 (36%), Positives = 106/185 (57%), Gaps = 10/185 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               VL +E ++  ++R +   IA++Y N          + + VL+G+  F AD+++   
Sbjct: 5   DIEKVLISEEQIQKKVRELGAIIAEEYKNTVP-------LAIGVLKGAMPFMADLLKRTD 57

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
            +     ++F+  SSYGH T S G V +  D    + G+ +L++EDI+D+ LTL  +VD 
Sbjct: 58  TY---LEMDFMAVSSYGHSTVSTGEVKILKDLDTSVEGRDILIVEDIIDSGLTLSYLVDL 114

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
            K  +  S+K +  +DKP GRK+   A+YV   VP+ FVVGYGLDY + YR +  V +LK
Sbjct: 115 FKYRKAKSVKIVTLLDKPTGRKVDLKADYVGFTVPHEFVVGYGLDYKEQYRNLPYVGVLK 174

Query: 189 PSVYE 193
           P+VY 
Sbjct: 175 PNVYS 179
>ref|YP_001320712.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus
           metalliredigens QYMF]
 gb|ABR49053.1| hypoxanthine phosphoribosyltransferase [Alkaliphilus
           metalliredigens QYMF]
          Length = 179

 Score =  289 bits (741), Expect = 9e-77,   Method: Composition-based stats.
 Identities = 67/186 (36%), Positives = 105/186 (56%), Gaps = 9/186 (4%)

Query: 8   DFATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRIL 67
           +     LF++ E+  R+  + ++I  DY        E  LVV+ VL+G+ +F  D+VR +
Sbjct: 3   NDIKETLFSQEEIAQRVEELGKQITADY------NHEEGLVVIGVLKGASIFLGDLVRKI 56

Query: 68  GDFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVD 127
                P  ++F+  SSYG  T+S G V +  D   +I  KH+L++EDI+DT LTL+ + +
Sbjct: 57  DR---PLSIDFMAVSSYGLSTESSGVVRILKDLDLEIEDKHILIVEDIVDTGLTLKYLTE 113

Query: 128 SLKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVIL 187
           +LK     SIK    +DKP  RK     +Y+  D+P+ F+VGYG+DY + YR +  +  L
Sbjct: 114 NLKSRNTKSIKVCTLLDKPARRKCDLPIDYIGFDIPDEFIVGYGIDYAEKYRNLPYIATL 173

Query: 188 KPSVYE 193
           K  VY 
Sbjct: 174 KSEVYR 179
>ref|YP_001256007.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum A
           str. ATCC 3502]
 ref|YP_001385841.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum A
           str. ATCC 19397]
 ref|YP_001389248.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum A
           str. Hall]
 ref|YP_001392880.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum F
           str. Langeland]
 ref|ZP_02615659.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum NCTC
           2916]
 ref|YP_001783166.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum B1
           str. Okra]
 emb|CAL85086.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum A
           str. ATCC 3502]
 gb|ABS32570.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum A
           str. ATCC 19397]
 gb|ABS38687.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum A
           str. Hall]
 gb|ABS42703.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum F
           str. Langeland]
 gb|ACA43780.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum B1
           str. Okra]
 gb|EDT80105.1| hypoxanthine phosphoribosyltransferase [Clostridium botulinum NCTC
           2916]
          Length = 181

 Score =  289 bits (740), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 60/185 (32%), Positives = 109/185 (58%), Gaps = 10/185 (5%)

Query: 9   FATSVLFTEAELHTRMRGVAQRIADDYSNCNLKPLENPLVVVSVLRGSFVFTADMVRILG 68
               +L +E ++ +++  +  +I+ DY   N       L++V +L+GS  F AD+++ + 
Sbjct: 7   DIEKILISEEQIQSKINELGDQISKDYDGKN-------LMLVGILKGSVPFMADLLKRIT 59

Query: 69  DFGVPTRVEFLRASSYGHDTKSCGRVDVKADGLCDIRGKHVLVLEDILDTALTLREVVDS 128
              +P  ++F+  SSYG+ T S G V +  D   +I GK +L++EDI+D+ +TL+ ++++
Sbjct: 60  ---IPCTMDFMAVSSYGNSTTSSGVVRILKDLDFEIEGKDILIVEDIIDSGITLKYLLEN 116

Query: 129 LKKSEPASIKTLVAIDKPGGRKIPFTAEYVVADVPNVFVVGYGLDYDQSYREVRDVVILK 188
           L+  +PASI     ++K   RK      Y+  +VP+ F+VGYGLD+ + YR +  + ILK
Sbjct: 117 LRARKPASINIACLLNKEERRKAEIDVHYLGFNVPDYFLVGYGLDFAEKYRNLPYIGILK 176

Query: 189 PSVYE 193
             VY+
Sbjct: 177 EEVYK 181
  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF excluding environmental samples
  from WGS projects
    Posted date:  May 23, 2008  5:56 PM
  Number of letters in database: 883,778,997
  Number of sequences in database:  2,617,685
  
  Database: /host/Blast/data/nr_perl/nr.01
    Posted date:  May 23, 2008  5:54 PM
  Number of letters in database: 976,759,346
  Number of sequences in database:  2,761,413
  
  Database: /host/Blast/data/nr_perl/nr.02
    Posted date:  May 23, 2008  5:48 PM
  Number of letters in database: 374,670,760
  Number of sequences in database:  1,165,270
  
  Database: /host/Blast/data/nr_perl/nr.03
    Posted date:  Apr 28, 2009  5:40 PM
  Number of letters in database: 114,943,120
  Number of sequences in database:  354,819
  
Lambda     K      H
   0.315    0.197    0.660 

Lambda     K      H
   0.267   0.0603    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,673,649,947
Number of Sequences: 6899187
Number of extensions: 327372072
Number of successful extensions: 665206
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 7513
Number of HSP's successfully gapped in prelim test: 2113
Number of HSP's that attempted gapping in prelim test: 650802
Number of HSP's gapped (non-prelim): 10256
length of query: 210
length of database: 2,350,152,223
effective HSP length: 128
effective length of query: 82
effective length of database: 1,467,056,287
effective search space: 120298615534
effective search space used: 120298615534
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 77 (33.7 bits)