BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= XP_822456.1__[Trypanosoma_brucei]
(471 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_822456.1| hexokinase [Trypanosoma brucei TREU927] >g... 931 0.0
emb|CAC69958.1| hexokinase [Trypanosoma brucei] 929 0.0
ref|XP_822457.1| hexokinase [Trypanosoma brucei TREU927] >g... 909 0.0
ref|XP_816463.1| hexokinase, putative [Trypanosoma cruzi st... 668 0.0
ref|XP_808992.1| hexokinase, putative [Trypanosoma cruzi st... 666 0.0
gb|AAL93565.1|AF488830_1 hexokinase [Trypanosoma cruzi] >gi... 665 0.0
ref|XP_001564741.1| hexokinase, putative [Leishmania brazil... 598 e-169
gb|AAT72300.1| hemoglobin receptor [Leishmania donovani] 586 e-165
ref|XP_001682958.1| hexokinase, putative [Leishmania major]... 585 e-165
ref|XP_001465336.1| hexokinase [Leishmania infantum JPCM5] ... 585 e-165
ref|XP_001465335.1| hexokinase [Leishmania infantum JPCM5] ... 584 e-165
ref|XP_001682957.1| hexokinase, putative [Leishmania major]... 584 e-165
gb|AAV32455.1| hexokinase [Leishmania infantum] 564 e-159
gb|AAV32456.1| hexokinase [Leishmania mexicana] 557 e-157
gb|AAV88622.1| hexokinase [Leishmania donovani] 546 e-153
gb|AAV32969.1| hexokinase [Leishmania tropica] 493 e-137
gb|AAI00649.1| Hexokinase 3 [Rattus norvegicus] >gi|1490398... 275 5e-72
gb|EDL94016.1| hexokinase 3, isoform CRA_b [Rattus norvegicus] 275 9e-72
ref|NP_071515.1| hexokinase 3 [Rattus norvegicus] >gi|12389... 273 2e-71
dbj|BAE24390.1| unnamed protein product [Mus musculus] >gi|... 271 1e-70
ref|NP_001028417.1| hexokinase 3 [Mus musculus] >gi|8328824... 270 1e-70
dbj|BAE37000.1| unnamed protein product [Mus musculus] 270 1e-70
dbj|BAE29220.1| unnamed protein product [Mus musculus] 270 1e-70
ref|XP_546212.2| PREDICTED: similar to Hexokinase type III ... 270 2e-70
gb|AAI17862.1| Hk3 protein [Mus musculus] 270 3e-70
dbj|BAE42341.1| unnamed protein product [Mus musculus] >gi|... 269 4e-70
ref|XP_001498596.1| PREDICTED: similar to Hexokinase 3 (whi... 269 4e-70
dbj|BAE42045.1| unnamed protein product [Mus musculus] 268 6e-70
ref|XP_453567.1| HXK_KLULA [Kluyveromyces lactis] >gi|38605... 268 7e-70
sp|Q9SEK3|HXK1_SPIOL Hexokinase-1 (SoHxK1) >gi|6594672|gb|A... 268 8e-70
ref|XP_001525198.1| hexokinase [Lodderomyces elongisporus N... 268 8e-70
dbj|BAE35470.1| unnamed protein product [Mus musculus] >gi|... 268 1e-69
ref|NP_985826.1| AFR279Cp [Ashbya gossypii ATCC 10895] >gi|... 267 1e-69
dbj|BAE29007.1| unnamed protein product [Mus musculus] 267 1e-69
emb|CAG09720.1| unnamed protein product [Tetraodon nigrovir... 267 1e-69
gb|AAI17861.1| Hk3 protein [Mus musculus] 267 2e-69
ref|NP_989543.1| hexokinase 2 [Gallus gallus] >gi|23821302|... 266 2e-69
emb|CAA43855.1| hexakinase [Kluyveromyces lactis] 266 3e-69
ref|NP_079406.3| hexokinase domain containing 1 [Homo sapie... 265 4e-69
dbj|BAF83713.1| unnamed protein product [Homo sapiens] 265 4e-69
ref|NP_998231.1| hexokinase 2 [Danio rerio] >gi|28278945|gb... 265 6e-69
emb|CAH71500.1| hexokinase domain containing 1 [Homo sapiens] 265 6e-69
gb|AAH12337.1| HKDC1 protein [Homo sapiens] 265 9e-69
ref|XP_421579.2| PREDICTED: similar to Hexokinase domain co... 263 2e-68
ref|XP_001086179.1| PREDICTED: hexokinase 3 [Macaca mulatta] 263 3e-68
ref|XP_717405.1| hexokinase II [Candida albicans SC5314] >g... 261 7e-68
ref|XP_001364147.1| PREDICTED: similar to Hexokinase domain... 261 7e-68
ref|XP_001760948.1| hexokinase protein HXK4 [Physcomitrella... 261 8e-68
ref|XP_001110556.1| PREDICTED: similar to hexokinase domain... 261 9e-68
emb|CAP36704.1| Hypothetical protein CBG19465 [Caenorhabdit... 261 9e-68
ref|NP_194642.1| ATHXK1 (GLUCOSE INSENSITIVE 2); ATP bindin... 260 1e-67
ref|XP_001137121.1| PREDICTED: hexokinase 3 isoform 1 [Pan ... 260 2e-67
ref|XP_518124.2| PREDICTED: hexokinase 3 isoform 2 [Pan tro... 260 2e-67
gb|AAH21278.1| HKDC1 protein [Homo sapiens] 260 2e-67
gb|AAX43272.1| hexokinase 3 [synthetic construct] 260 2e-67
gb|AAH28129.1| Hexokinase 3 (white cell) [Homo sapiens] >gi... 260 2e-67
ref|NP_002106.1| hexokinase 3 [Homo sapiens] >gi|1708363|sp... 260 2e-67
ref|XP_001386689.2| Hexokinase [Pichia stipitis CBS 6054] >... 259 2e-67
ref|NP_663394.1| hexokinase domain containing 1 [Mus muscul... 259 3e-67
ref|NP_001090603.1| hypothetical protein LOC100036846 [Xeno... 259 3e-67
gb|EAZ03118.1| hypothetical protein OsI_024350 [Oryza sativ... 259 3e-67
ref|NP_001075245.1| hexokinase II [Equus caballus] >gi|1463... 259 4e-67
emb|CAA86511.1| Human hexokinase II cDNA [Homo sapiens] 259 4e-67
gb|EAW99603.1| hexokinase 2, isoform CRA_b [Homo sapiens] 259 4e-67
ref|NP_001044214.1| Os01g0742500 [Oryza sativa (japonica cu... 258 5e-67
ref|NP_001059124.1| Os07g0197100 [Oryza sativa (japonica cu... 258 7e-67
ref|XP_001111706.1| PREDICTED: similar to hexokinase 2 isof... 258 7e-67
gb|AAS60195.1| hexokinase 4a [Nicotiana tabacum] 258 8e-67
gb|AAL60584.1|AF454962_1 hexokinase [Brassica oleracea] 258 8e-67
ref|XP_001162535.1| PREDICTED: hexokinase 2 isoform 2 [Pan ... 258 9e-67
ref|NP_000180.2| hexokinase 2 [Homo sapiens] >gi|56405344|s... 258 9e-67
dbj|BAF83046.1| unnamed protein product [Homo sapiens] 258 9e-67
emb|CAA86476.2| hexokinase II [Homo sapiens] 257 1e-66
pdb|2NZT|A Chain A, Crystal Structure Of Human Hexokinase I... 257 1e-66
gb|AAS60196.1| hexokinase 4b [Nicotiana tabacum] 257 1e-66
gb|ABS89273.1| hexokinase 1b [Gadus morhua] 257 1e-66
ref|XP_001111663.1| PREDICTED: similar to hexokinase 2 isof... 257 1e-66
ref|XP_001162408.1| PREDICTED: hexokinase 2 isoform 1 [Pan ... 257 1e-66
ref|XP_702631.1| PREDICTED: hypothetical protein [Danio rer... 257 1e-66
ref|NP_998417.1| hexokinase 1 [Danio rerio] >gi|28856173|gb... 257 1e-66
ref|XP_001247226.1| hexokinase [Coccidioides immitis RS] >g... 257 2e-66
ref|XP_546137.2| PREDICTED: similar to hexokinase domain co... 257 2e-66
gb|EAY98804.1| hypothetical protein OsI_020037 [Oryza sativ... 257 2e-66
dbj|BAE26802.1| unnamed protein product [Mus musculus] 257 2e-66
gb|AAA34699.1| hexokinase (HXK2) 256 2e-66
ref|XP_001381777.1| PREDICTED: similar to hexokinase II [Mo... 256 2e-66
gb|AAA34697.1| hexokinase P-II peptide >gi|224664|prf||1110... 256 3e-66
ref|NP_036867.1| hexokinase 2 [Rattus norvegicus] >gi|12389... 256 3e-66
sp|P17710|HXK1_MOUSE Hexokinase-1 (Hexokinase type I) (HK I... 256 4e-66
ref|NP_034568.1| hexokinase 1 [Mus musculus] >gi|1850140|gb... 256 4e-66
ref|XP_001255832.1| PREDICTED: similar to hexokinase II, pa... 256 4e-66
ref|XP_001110396.1| PREDICTED: similar to hexokinase 1 isof... 256 4e-66
ref|XP_001110227.1| PREDICTED: similar to hexokinase 1 isof... 256 4e-66
dbj|BAE25472.1| unnamed protein product [Mus musculus] 256 4e-66
gb|EDL32105.1| hexokinase 1, isoform CRA_c [Mus musculus] 256 4e-66
ref|NP_038848.1| hexokinase 2 [Mus musculus] >gi|2495218|sp... 256 4e-66
gb|EDL92983.1| hexokinase 1, isoform CRA_d [Rattus norvegicus] 256 4e-66
gb|EDL32103.1| hexokinase 1, isoform CRA_a [Mus musculus] 256 4e-66
gb|EDL32108.1| hexokinase 1, isoform CRA_f [Mus musculus] 256 4e-66
sp|Q2KNB9|HXK2_ORYSJ Hexokinase-2 (Hexokinase-3) >gi|621307... 256 4e-66
gb|EDL92981.1| hexokinase 1, isoform CRA_b [Rattus norvegicus] 256 4e-66
emb|CAF97272.1| unnamed protein product [Tetraodon nigrovir... 255 4e-66
gb|EDL92989.1| hexokinase 1, isoform CRA_j [Rattus norvegicus] 255 4e-66
ref|XP_532991.2| PREDICTED: similar to hexokinase 2 [Canis ... 255 5e-66
gb|AAA60333.1| hexokinase [Arabidopsis thaliana] >gi|158238... 255 5e-66
gb|EDL32104.1| hexokinase 1, isoform CRA_b [Mus musculus] 255 5e-66
gb|EDL92982.1| hexokinase 1, isoform CRA_c [Rattus norvegicus] 255 5e-66
gb|EDL92984.1| hexokinase 1, isoform CRA_e [Rattus norvegicus] 255 5e-66
gb|EDL92985.1| hexokinase 1, isoform CRA_f [Rattus norvegicus] 255 5e-66
ref|XP_001110269.1| PREDICTED: similar to hexokinase 1 isof... 255 5e-66
ref|XP_001110350.1| PREDICTED: similar to hexokinase 1 isof... 255 5e-66
gb|EDL92986.1| hexokinase 1, isoform CRA_g [Rattus norvegicus] 255 6e-66
gb|EDL92980.1| hexokinase 1, isoform CRA_a [Rattus norvegicus] 255 6e-66
gb|EDL92990.1| hexokinase 1, isoform CRA_k [Rattus norvegicus] 255 6e-66
gb|EDL92987.1| hexokinase 1, isoform CRA_h [Rattus norvegicus] 255 6e-66
ref|NP_036866.1| hexokinase 1 [Rattus norvegicus] >gi|62266... 255 6e-66
ref|XP_001502742.1| PREDICTED: similar to hexokinase domain... 255 6e-66
gb|AAH72628.1| Hk1 protein [Mus musculus] >gi|148700159|gb|... 255 6e-66
gb|EDL92988.1| hexokinase 1, isoform CRA_i [Rattus norvegicus] 255 6e-66
gb|EDL32107.1| hexokinase 1, isoform CRA_e [Mus musculus] 255 7e-66
gb|AAA41334.1| hexokinase type II 255 7e-66
dbj|BAE39552.1| unnamed protein product [Mus musculus] 255 7e-66
ref|XP_001380968.1| PREDICTED: similar to Hexokinase 3 (whi... 254 7e-66
ref|XP_460972.1| hypothetical protein DEHA0F15169g [Debaryo... 254 9e-66
gb|AAY24209.1| unknown [Homo sapiens] 254 9e-66
gb|AAA37804.1| hexokinase (EC 2.7.1.1) 254 9e-66
gb|AAY60841.1| hexokinase [Solanum lycopersicum] 254 1e-65
ref|NP_001120545.1| hypothetical protein LOC100145699 [Xeno... 254 1e-65
dbj|BAE36411.1| unnamed protein product [Mus musculus] 254 1e-65
gb|AAF28854.1| hexokinase I [Cyprinus carpio] 254 1e-65
sp|Q1WM16|HXK7_ORYSJ Hexokinase-7 (Hexokinase-6) >gi|621307... 253 2e-65
gb|AAZ93624.1| hexokinase 7 [Oryza sativa (japonica cultiva... 253 2e-65
gb|AAS60197.1| hexokinase 5 [Nicotiana tabacum] 253 2e-65
emb|CAH18060.1| hypothetical protein [Homo sapiens] 253 2e-65
emb|CAH65327.1| hypothetical protein [Gallus gallus] 253 3e-65
ref|NP_001116459.1| hexokinase 2 [Sus scrofa] >gi|122134685... 253 3e-65
ref|XP_870563.2| PREDICTED: similar to hexokinase II [Bos t... 252 4e-65
ref|XP_965673.2| hexokinase [Neurospora crassa OR74A] >gi|1... 252 4e-65
dbj|BAF84701.1| unnamed protein product [Homo sapiens] 252 4e-65
gb|AAB91396.1| mutant type II hexokinase [Rattus norvegicus] 252 5e-65
ref|XP_001169215.1| PREDICTED: hexokinase 1 isoform 8 [Pan ... 252 6e-65
ref|NP_277031.1| hexokinase 1 isoform HKI-R [Homo sapiens] ... 252 6e-65
ref|NP_989432.1| hexokinase 1 [Gallus gallus] >gi|23821300|... 251 6e-65
ref|XP_001169044.1| PREDICTED: hexokinase 1 isoform 1 [Pan ... 251 6e-65
gb|EAW54323.1| hexokinase 1, isoform CRA_d [Homo sapiens] 251 6e-65
ref|NP_277032.1| hexokinase 1 isoform HKI-ta/tb [Homo sapie... 251 6e-65
ref|NP_277035.2| hexokinase 1 isoform HKI-td [Homo sapiens] 251 6e-65
ref|NP_000179.2| hexokinase 1 isoform HKI [Homo sapiens] >g... 251 6e-65
ref|XP_001169069.1| PREDICTED: hexokinase 1 isoform 2 [Pan ... 251 6e-65
gb|AAQ02439.1| hexokinase 1 [synthetic construct] 251 7e-65
pdb|1CZA|N Chain N, Mutant Monomer Of Recombinant Human Hex... 251 7e-65
dbj|BAD92763.1| hexokinase 1 isoform HKI variant [Homo sapi... 251 7e-65
ref|XP_507830.2| PREDICTED: hexokinase 1 isoform 10 [Pan tr... 251 7e-65
sp|Q5RC71|HXK1_PONPY Hexokinase-1 (Hexokinase type I) (HK I... 251 7e-65
gb|AAF82320.1|AAF82320 hexokinase 1 isoform td [Homo sapien... 251 8e-65
ref|XP_001169123.1| PREDICTED: hexokinase 1 isoform 4 [Pan ... 251 8e-65
ref|NP_001108597.1| hexokinase domain containing 1 [Danio r... 251 8e-65
ref|NP_776744.1| FK506 binding protein 12-rapamycin associa... 251 9e-65
ref|XP_001380610.1| PREDICTED: similar to hexokinase 1, [Mo... 251 9e-65
ref|NP_116711.1| Hexokinase isoenzyme 1, a cytosolic protei... 251 9e-65
ref|NP_001096201.1| hexokinase 1 [Xenopus tropicalis] >gi|1... 251 1e-64
emb|CAF90567.1| unnamed protein product [Tetraodon nigrovir... 251 1e-64
ref|NP_179576.1| ATHXK2 (HEXOKINASE 2); ATP binding / hexok... 250 2e-64
gb|EDN59204.1| hexokinase I (PI) (also called hexokinase A)... 250 2e-64
ref|XP_001379711.1| PREDICTED: similar to glucokinase [Mono... 250 2e-64
ref|XP_001333260.1| PREDICTED: similar to Hexokinase domain... 250 2e-64
ref|XP_001635171.1| predicted protein [Nematostella vectens... 249 2e-64
pdb|1HKC|A Chain A, Recombinant Human Hexokinase Type I Com... 249 2e-64
ref|XP_444978.1| hypothetical protein CAGL0A04829g [Candida... 249 2e-64
pdb|1DGK|N Chain N, Mutant Monomer Of Recombinant Human Hex... 249 2e-64
ref|NP_001096321.1| hypothetical protein LOC100124905 [Xeno... 249 3e-64
gb|AAO24584.1| At2g19860 [Arabidopsis thaliana] >gi|1107436... 249 3e-64
gb|AAG28503.1|AF196966_1 hexokinase [Citrus sinensis] 249 3e-64
gb|AAA52646.1| hexokinase 1 [Homo sapiens] 249 4e-64
ref|XP_001762951.1| hexokinase protein HXK6 [Physcomitrella... 249 5e-64
emb|CAA27202.1| unnamed protein product [Saccharomyces cere... 248 6e-64
ref|XP_536376.2| PREDICTED: similar to Hexokinase, type I (... 248 7e-64
gb|EAZ13494.1| hypothetical protein OsJ_003319 [Oryza sativ... 248 7e-64
gb|ABS89272.1| hexokinase 1a [Gadus morhua] 248 7e-64
gb|AAA34698.1| hexokinase (HXK1) 248 7e-64
ref|XP_001850122.1| hexokinase [Culex pipiens quinquefascia... 248 9e-64
ref|NP_001042264.1| Os01g0190400 [Oryza sativa (japonica cu... 248 1e-63
ref|NP_001096656.1| hexokinase I [Xenopus laevis] >gi|49114... 247 1e-63
emb|CAA47379.1| hexokinase type 1 [Homo sapiens] 247 1e-63
sp|Q1WM15|HXK8_ORYSJ Hexokinase-8 (Hexokinase-4) >gi|557713... 247 1e-63
gb|AAZ93625.1| hexokinase 8 [Oryza sativa (japonica cultiva... 247 1e-63
gb|AAL60583.1|AF454961_1 hexokinase [Brassica oleracea] 247 1e-63
gb|AAS60194.1| hexokinase 3 [Nicotiana tabacum] 247 1e-63
ref|NP_001012686.1| hexokinase 1 [Bos taurus] >gi|33332343|... 247 2e-63
ref|XP_001772444.1| hexokinase protein HXK1 [Physcomitrella... 247 2e-63
gb|AAT77515.1| hexokinase 7 [Nicotiana tabacum] 247 2e-63
gb|AAQ72424.1| hexokinase PpHxk1 [Physcomitrella patens] >g... 246 2e-63
ref|XP_001360104.1| GA20820-PA [Drosophila pseudoobscura] >... 246 2e-63
ref|XP_001597079.1| hypothetical protein SS1G_01273 [Sclero... 246 2e-63
ref|XP_001898658.1| hexokinase [Brugia malayi] >gi|15859392... 246 2e-63
gb|AAY83348.1| hexokinase [Hypocrea jecorina] 246 2e-63
gb|AAG18422.1|AF288471_1 hexokinase I [Xenopus laevis] 246 4e-63
ref|XP_001766433.1| hexokinase protein HXK5 [Physcomitrella... 246 4e-63
gb|AAG28789.1|AF309088_1 hexokinase [Tuber borchii] 245 5e-63
ref|XP_001660030.1| hexokinase [Aedes aegypti] >gi|10887452... 245 6e-63
gb|AAU05129.1| hexokinase [Aedes aegypti] 245 6e-63
ref|NP_001021106.1| F14B4.2a [Caenorhabditis elegans] >gi|3... 245 7e-63
emb|CAG05683.1| unnamed protein product [Tetraodon nigrovir... 245 7e-63
ref|NP_001079298.1| glucokinase [Xenopus laevis] >gi|126284... 245 7e-63
emb|CAO65442.1| unnamed protein product [Vitis vinifera] 244 9e-63
ref|XP_001660031.1| hexokinase [Aedes aegypti] >gi|10887452... 244 9e-63
ref|NP_001021107.1| F14B4.2b [Caenorhabditis elegans] >gi|5... 244 1e-62
emb|CAN83149.1| hypothetical protein [Vitis vinifera] 244 1e-62
ref|XP_001912895.1| unnamed protein product [Podospora anse... 243 2e-62
ref|XP_001754148.1| hexokinase protein HXK7 [Physcomitrella... 243 2e-62
ref|NP_011261.1| Hexokinase isoenzyme 2 that catalyzes phos... 243 2e-62
emb|CAA27203.1| unnamed protein product [Saccharomyces cere... 243 2e-62
ref|XP_001520120.1| PREDICTED: similar to glucokinase [Orni... 243 2e-62
ref|XP_001549109.1| hexokinase [Botryotinia fuckeliana B05.... 243 2e-62
gb|EEH35125.1| glucokinase [Paracoccidioides brasiliensis P... 242 4e-62
ref|NP_034422.2| glucokinase [Mus musculus] >gi|1708365|sp|... 242 4e-62
emb|CAJ28915.1| hexokinase [Crassostrea gigas] 242 5e-62
emb|CAC81350.1| hexokinase [Solanum lycopersicum] 242 5e-62
gb|EEH43130.1| glucokinase [Paracoccidioides brasiliensis P... 241 7e-62
sp|P50506|HXK_DEBOC Hexokinase >gi|1041966|gb|AAB34892.1| h... 241 7e-62
ref|XP_001899820.1| Hexokinase family protein [Brugia malay... 241 7e-62
gb|EAY96818.1| hypothetical protein OsI_018051 [Oryza sativ... 241 9e-62
gb|AAC42074.1| glucokinase >gi|15029832|gb|AAH11139.1| Gck ... 241 1e-61
ref|XP_970645.1| PREDICTED: similar to CG3001-PA, isoform A... 241 1e-61
ref|XP_001390866.1| hypothetical protein An06g00380 [Asperg... 241 1e-61
gb|AAS60192.1| hexokinase 1a [Nicotiana tabacum] 241 1e-61
ref|XP_001517802.1| PREDICTED: similar to HKDC1 protein [Or... 240 1e-61
ref|XP_001260212.1| hexokinase Kxk, putative [Neosartorya f... 240 2e-61
gb|AAU05128.1| hexokinase [Aedes albopictus] 240 2e-61
emb|CAG05684.1| unnamed protein product [Tetraodon nigrovir... 240 2e-61
ref|XP_001265599.1| hexokinase [Neosartorya fischeri NRRL 1... 240 2e-61
sp|Q9SQ76|HXK2_SOLTU Hexokinase-2 (StHK2) >gi|6492118|gb|AA... 240 2e-61
gb|AAP40021.1| hexokinase [Nicotiana benthamiana] 240 2e-61
emb|CAB40412.1| hexokinase [Haemonchus contortus] 239 3e-61
ref|XP_798648.1| PREDICTED: similar to hexokinase I [Strong... 239 3e-61
ref|XP_001275241.1| hexokinase Kxk, putative [Aspergillus c... 239 3e-61
sp|Q6Q8A5|HXK2_TOBAC Hexokinase-2, chloroplast precursor (N... 239 3e-61
gb|ABA01010.1| hexokinase [Solanum chacoense] 239 3e-61
gb|EAY75659.1| hypothetical protein OsI_003506 [Oryza sativ... 239 3e-61
gb|AAT77513.1| hexokinase 3 [Nicotiana sylvestris] 239 3e-61
ref|NP_592948.1| hexokinase 1 (PMID 8549830) [Schizosacchar... 239 3e-61
sp|P17712|HXK4_RAT Glucokinase (Hexokinase-4) (Hexokinase t... 239 3e-61
ref|XP_749720.1| hexokinase Kxk [Aspergillus fumigatus Af29... 239 3e-61
gb|EDU44499.1| hexokinase [Pyrenophora tritici-repentis Pt-... 239 4e-61
ref|NP_001117721.1| glucokinase [Oncorhynchus mykiss] >gi|7... 239 4e-61
ref|NP_036697.1| glucokinase [Rattus norvegicus] >gi|56240|... 239 5e-61
ref|XP_364444.1| hexokinase [Magnaporthe grisea 70-15] >gi|... 239 5e-61
ref|NP_277042.1| glucokinase isoform 2 [Homo sapiens] >gi|2... 239 5e-61
ref|XP_001143590.1| PREDICTED: glucokinase isoform 2 [Pan t... 239 5e-61
gb|EAY77169.1| hypothetical protein OsI_005016 [Oryza sativ... 239 5e-61
ref|NP_001095772.1| glucokinase [Bos taurus] >gi|151554675|... 238 6e-61
gb|AAL55635.1|AF118134_1 hexokinase-related protein 1 [Sola... 238 6e-61
gb|EEH38094.1| hexokinase [Paracoccidioides brasiliensis Pb01] 238 6e-61
ref|XP_001110189.1| PREDICTED: similar to hexokinase 1 isof... 238 7e-61
gb|AAB59563.1| glucokinase 238 8e-61
ref|NP_277043.1| glucokinase isoform 3 [Homo sapiens] >gi|2... 238 9e-61
ref|XP_001143302.1| PREDICTED: glucokinase isoform 1 [Pan t... 238 9e-61
pdb|1V4T|A Chain A, Crystal Structure Of Human Glucokinase 238 9e-61
ref|NP_001056082.1| Os05g0522500 [Oryza sativa (japonica cu... 238 1e-60
gb|AAP36837.1| Homo sapiens glucokinase (hexokinase 4, matu... 238 1e-60
pdb|1V4S|A Chain A, Crystal Structure Of Human Glucokinase 238 1e-60
ref|NP_000153.1| glucokinase isoform 1 [Homo sapiens] >gi|5... 238 1e-60
gb|EAY98739.1| hypothetical protein OsI_019972 [Oryza sativ... 237 1e-60
ref|NP_175220.2| hexokinase, putative [Arabidopsis thaliana... 237 1e-60
ref|XP_001143661.1| PREDICTED: glucokinase isoform 3 [Pan t... 237 1e-60
ref|XP_001093035.1| PREDICTED: similar to glucokinase isofo... 237 1e-60
sp|Q26609|HXK_SCHMA Hexokinase >gi|157830239|pdb|1BDG|A Cha... 237 1e-60
ref|XP_717498.1| hexokinase II [Candida albicans SC5314] >g... 237 1e-60
gb|AAY60842.1| plastidic hexokinase [Solanum lycopersicum] 237 1e-60
gb|ABS31137.1| glucokinase [Homo sapiens] 237 2e-60
ref|XP_380676.1| hypothetical protein FG00500.1 [Gibberella... 237 2e-60
ref|XP_001092919.1| PREDICTED: similar to glucokinase isofo... 237 2e-60
gb|AAG35735.1|AF208543_1 hexokinase [Lycopersicon esculentum] 237 2e-60
ref|XP_001770177.1| hexokinase protein HXK9 [Physcomitrella... 237 2e-60
gb|AAC33587.2| glucokinase [Cyprinus carpio] 236 2e-60
gb|EEH47729.1| hexokinase [Paracoccidioides brasiliensis Pb18] 236 2e-60
sp|Q2KNB4|HXK3_ORYSJ Hexokinase-3 (Hexokinase-8) >gi|621307... 236 2e-60
ref|XP_001487588.1| hypothetical protein PGUG_00965 [Pichia... 236 2e-60
ref|XP_001784630.1| hexokinase protein HXK2 [Physcomitrella... 236 2e-60
sp|Q9SEK2|HXK1_TOBAC Hexokinase-1 (NtHxK1) >gi|6594674|gb|A... 236 3e-60
gb|AAG22929.1|AF257623_1 hexokinase-C [Drosophila simulans]... 236 3e-60
ref|XP_001495888.1| PREDICTED: similar to glucokinase [Equu... 236 3e-60
ref|NP_001105529.1| hexokinase [Zea mays] >gi|21954124|gb|A... 236 3e-60
ref|NP_727350.1| Hexokinase A CG3001-PB, isoform B [Drosoph... 236 3e-60
gb|AAR13363.1| hexokinase [Brugia malayi] 236 4e-60
ref|NP_524674.1| Hexokinase C CG8094-PA [Drosophila melanog... 235 5e-60
gb|AAG23066.1|AF257542_1 hexokinase-C [Drosophila melanogas... 235 5e-60
gb|AAG23076.1|AF257552_1 hexokinase-C [Drosophila melanogas... 235 5e-60
gb|AAG23068.1|AF257544_1 hexokinase-C [Drosophila melanogas... 235 5e-60
gb|AAF40309.1|AF169368_1 glucokinase [Sparus aurata] 235 6e-60
ref|XP_786955.1| PREDICTED: similar to hexokinase II [Stron... 235 6e-60
ref|NP_524848.1| Hexokinase A CG3001-PA, isoform A [Drosoph... 235 6e-60
gb|ABI49144.1| hexokinase [Trimastix pyriformis] 235 6e-60
ref|NP_001077423.1| glucokinase [Felis catus] >gi|125434898... 235 6e-60
gb|AAC50422.1| ATP:D-hexose 6-phosphotransferase 235 7e-60
gb|AAG23108.1|AF257584_1 hexokinase-C [Drosophila melanogas... 235 7e-60
emb|CAO60993.1| unnamed protein product [Vitis vinifera] 235 7e-60
gb|AAC33585.2| glucokinase [Sparus aurata] 234 8e-60
ref|XP_001776765.1| hexokinase protein HXK10 [Physcomitrell... 234 9e-60
ref|XP_001819202.1| hypothetical protein [Aspergillus oryza... 234 1e-59
>ref|XP_822456.1| hexokinase [Trypanosoma brucei TREU927]
gb|EAN77628.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 931 bits (2407), Expect = 0.0, Method: Composition-based stats.
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
>emb|CAC69958.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 929 bits (2400), Expect = 0.0, Method: Composition-based stats.
Identities = 470/471 (99%), Positives = 470/471 (99%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLF FIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFDFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
>ref|XP_822457.1| hexokinase [Trypanosoma brucei TREU927]
gb|EAN77629.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 909 bits (2350), Expect = 0.0, Method: Composition-based stats.
Identities = 460/471 (97%), Positives = 465/471 (98%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLF FIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFDFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTV T+ISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVATMISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPI+MESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPISMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAK GSG+GAA ISA+V + K
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKGGSGVGAALISAIVADGK 471
>ref|XP_816463.1| hexokinase, putative [Trypanosoma cruzi strain CL Brener]
gb|EAN94612.1| hexokinase, putative [Trypanosoma cruzi]
Length = 471
Score = 668 bits (1724), Expect = 0.0, Method: Composition-based stats.
Identities = 316/471 (67%), Positives = 385/471 (81%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MS RLNN+L+HI+++ D +T+R +K+ +A+A+L NQFT+ + ++Q+M Y+++EM+EGL
Sbjct: 1 MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHEMIEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGREST+RMLPSYVYK DP +ATGVFYALDLGGTNFRVLRV CKEG V D + F IP+
Sbjct: 61 EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL+G A DLFGFIA +VKK ME +APEDLNRTVPLGFTFSFP EQ V+ G LI+WTKG
Sbjct: 121 QALQGTAEDLFGFIAQSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDHGFLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FST+GV+G DV+ LLQ A R+ +KV VVALCNDTVGTLI++YF DP+ QVGVIIGTGSN
Sbjct: 181 FSTRGVEGKDVVELLQKALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE A AVTK+P+VAARG+ TPINME GNFDSKY+FVLP T +D +D + N+ Q
Sbjct: 241 ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNYQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EKM+SGMYLGEI+RR+I HL+ ++CLP+AL + + SFE++F GMISADRMPGLQF
Sbjct: 301 TQEKMVSGMYLGEISRRMIAHLAELHCLPSALASKMAKPWSFETKFMGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR Q++ VDV + DL +IRDVC LVRGRAAQ+SA FC APLVKT+ +GRAT+AIDG
Sbjct: 361 TRQVFQELFHVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEK PSFRR+LQ N+N ILGP CDV LA+DGSGIGAAFISA+VVNDK
Sbjct: 421 SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK 471
>ref|XP_808992.1| hexokinase, putative [Trypanosoma cruzi strain CL Brener]
gb|EAN87141.1| hexokinase, putative [Trypanosoma cruzi]
Length = 471
Score = 666 bits (1718), Expect = 0.0, Method: Composition-based stats.
Identities = 316/471 (67%), Positives = 385/471 (81%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MS RLNN+L+HI+++ D +T+R +K+ +A+A+L NQFT+ + ++Q+M Y+++EM+EGL
Sbjct: 1 MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHEMIEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGREST+RMLPSYVYK DP +ATGVFYALDLGGTNFRVLRV CKEG V D + F IP+
Sbjct: 61 EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL+G A DLFGFIA +VKK ME +APEDLNRTVPLGFTFSFP EQ V+ G LI+WTKG
Sbjct: 121 QALQGTAEDLFGFIAKSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDNGFLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FST+GV+G DV+ LLQ A R+ +KV VVALCNDTVGTLI++YF DP+ QVGVIIGTGSN
Sbjct: 181 FSTRGVEGKDVVELLQNALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE A AVTK+P+VAARG+ TPINME GNFDSKY+FVLP T +D +D + N+ Q
Sbjct: 241 ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNYQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EKM+SGMYLGEI+RR+I HL+ + CLP+AL + + SFE++F GMISADRMPGLQF
Sbjct: 301 TQEKMVSGMYLGEISRRMIAHLAELRCLPSALASKMAKPWSFETKFMGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR +Q++ VDV + DL +IRDVC LVRGRAAQ+SA FC APLVKT+ +GRAT+AIDG
Sbjct: 361 TRQVLQELFHVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEK PSFRR+LQ N+N ILGP CDV LA+DGSGIGAAFISA+VVNDK
Sbjct: 421 SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK 471
>gb|AAL93565.1|AF488830_1 hexokinase [Trypanosoma cruzi]
emb|CAD26835.1| hexokinase [Trypanosoma cruzi]
Length = 471
Score = 665 bits (1716), Expect = 0.0, Method: Composition-based stats.
Identities = 315/471 (66%), Positives = 385/471 (81%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MS RLNN+L+HI+++ D +T+R +K+ +A+A+L NQFT+ + ++Q+M Y++++M+EGL
Sbjct: 1 MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHQMIEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGREST+RMLPSYVYK DP +ATGVFYALDLGGTNFRVLRV CKEG V D + F IP+
Sbjct: 61 EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL+G A DLFGFIA +VKK ME +APEDLNRTVPLGFTFSFP EQ V+ G LI+WTKG
Sbjct: 121 QALQGTAEDLFGFIAQSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDHGFLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FST+GV+G DV+ LLQ A R+ +KV VVALCNDTVGTLI++YF DP+ QVGVIIGTGSN
Sbjct: 181 FSTRGVEGKDVVELLQKALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE A AVTK+P+VAARG+ TPINME GNFDSKY+FVLP T +D +D + N+ Q
Sbjct: 241 ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNFQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EKM+SGMYLGEI+RR+I HL+ ++CLP+AL + + SFE++F GMISADRMPGLQF
Sbjct: 301 TQEKMVSGMYLGEISRRMIAHLAELHCLPSALASKMAKPWSFETKFMGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR Q++ VDV + DL +IRDVC LVRGRAAQ+SA FC APLVKT+ +GRAT+AIDG
Sbjct: 361 TRQVFQELFQVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEK PSFRR+LQ N+N ILGP CDV LA+DGSGIGAAFISA+VVNDK
Sbjct: 421 SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK 471
>ref|XP_001564741.1| hexokinase, putative [Leishmania braziliensis MHOM/BR/75/M2904]
emb|CAM38811.1| hexokinase, putative [Leishmania braziliensis]
Length = 471
Score = 598 bits (1543), Expect = e-169, Method: Composition-based stats.
Identities = 286/471 (60%), Positives = 367/471 (77%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN++ H++I+ +D E +R +K+ +A+A+L+ QFTM+ E M+Q+ Y++YEMVEGL
Sbjct: 1 MASRVNNLMNHLAIRDSDSEEMRYIKQRLALASLSTQFTMASEKMKQLTMYMVYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPSYVY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D S F IPK
Sbjct: 61 EGRPSTVRMLPSYVYTSDPAKATGVYYALDLGGTNFRVLRVSLRSGKVDDRIDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL GN+ +LF FIA +VKK M APEDL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALTGNSANLFDFIAQSVKKMMSENAPEDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQ + R+ + VNVVALCNDTVGTL++ YF D QVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQGSLRRMHINVNVVALCNDTVGTLVARYFVDTNAQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV ARG+A+TPINME GNFDSKY++ LPTT +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVCARGNAVTPINMECGNFDSKYKYALPTTVYDDEMDAITPNRDHQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L LG +FES+ GM++AD+MPGLQF
Sbjct: 301 RQEKIVSGMYLGEISRRMIVHLAQLGCLPRDLVDGLGKPWAFESKHMGMVAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I++V GV+V + DL IR++C LVR RAAQ +A AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRVAGVNVTDVADLHTIREICCLVRNRAAQQAAVLSAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK+PSF+R+ Q+ I ILGP + + VL KDGSG+GAA I A+ N K
Sbjct: 421 SVYEKVPSFQRLYQECITGILGPTSNAKVVLQKDGSGVGAAMICALAANQK 471
>gb|AAT72300.1| hemoglobin receptor [Leishmania donovani]
Length = 471
Score = 586 bits (1511), Expect = e-165, Method: Composition-based stats.
Identities = 291/471 (61%), Positives = 369/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+++ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MATRVNNLLSHIALRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVDV + DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDVTDMSDLHTIRETCCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL KDGSG+GAA I A+ VN K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQKDGSGVGAAMICALAVNKK 471
>ref|XP_001682958.1| hexokinase, putative [Leishmania major]
emb|CAJ03835.1| hexokinase, putative [Leishmania major]
Length = 471
Score = 585 bits (1509), Expect = e-165, Method: Composition-based stats.
Identities = 291/471 (61%), Positives = 369/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MAARVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVD+ I DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDMADISDLHTIRETCCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL +DGSG+GAA I A+ VN K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQRDGSGVGAAMICALAVNTK 471
>ref|XP_001465336.1| hexokinase [Leishmania infantum JPCM5]
emb|CAM67757.1| hexokinase, putative [Leishmania infantum]
Length = 471
Score = 585 bits (1509), Expect = e-165, Method: Composition-based stats.
Identities = 291/471 (61%), Positives = 368/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MATRVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVDV + DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDVTDMSDLHTIREACCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL KDGSG+GAA I A+ N K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQKDGSGVGAAMICALAANKK 471
>ref|XP_001465335.1| hexokinase [Leishmania infantum JPCM5]
emb|CAM67756.1| hexokinase, putative [Leishmania infantum]
Length = 471
Score = 584 bits (1506), Expect = e-165, Method: Composition-based stats.
Identities = 290/471 (61%), Positives = 368/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MATRVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVDV + DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDVTDMSDLHTIREACCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL +DGSG+GAA I A+ N K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQRDGSGVGAAMICALAANKK 471
>ref|XP_001682957.1| hexokinase, putative [Leishmania major]
gb|AAV32454.1| hexokinase [Leishmania major]
emb|CAJ03833.1| hexokinase, putative [Leishmania major]
Length = 471
Score = 584 bits (1505), Expect = e-165, Method: Composition-based stats.
Identities = 290/471 (61%), Positives = 368/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MAARVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVD+ I DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDMADISDLHTIRETCCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL +DGSG+GAA I A+ N K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQRDGSGVGAAMICALAANTK 471
>gb|AAV32455.1| hexokinase [Leishmania infantum]
Length = 451
Score = 564 bits (1453), Expect = e-159, Method: Composition-based stats.
Identities = 281/449 (62%), Positives = 352/449 (78%)
Query: 18 DGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKA 77
D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGLEGR STVRMLPS+VY +
Sbjct: 1 DSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGLEGRPSTVRMLPSFVYTS 60
Query: 78 DPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASN 137
DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK AL G+ATDLF FIA +
Sbjct: 61 DPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPKSALVGDATDLFDFIAQS 120
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKGFSTK V+GNDV+ LLQA
Sbjct: 121 VKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKGFSTKNVEGNDVVELLQA 180
Query: 198 AFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVA 257
+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSNACYFE ASAVTKDPAV+
Sbjct: 181 SLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSNACYFERASAVTKDPAVS 240
Query: 258 ARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARR 317
ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q EK++SGMYLGEI+RR
Sbjct: 241 ARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQRQEKLVSGMYLGEISRR 300
Query: 318 VIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQFTR I+++ GVDV +
Sbjct: 301 LIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQFTRELIKRIAGVDVTDMS 360
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNI 437
DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DGSV+EK PSF+R+ Q+ I
Sbjct: 361 DLHTIREACCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDGSVYEKTPSFQRLYQECI 420
Query: 438 NRILGPECDVRAVLAKDGSGIGAAFISAM 466
ILG +V+ VL KDGSG+GAA I A+
Sbjct: 421 TSILGSTSNVKVVLQKDGSGVGAAMICAL 449
>gb|AAV32456.1| hexokinase [Leishmania mexicana]
Length = 451
Score = 557 bits (1436), Expect = e-157, Method: Composition-based stats.
Identities = 278/449 (61%), Positives = 349/449 (77%)
Query: 18 DGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKA 77
D E +R + + +A+A+L QFTMS E M+Q+ Y+++EMVEGLEGR STVRMLPS+VY +
Sbjct: 1 DSEEMRYITQRLALASLATQFTMSPEKMKQLTMYMIHEMVEGLEGRPSTVRMLPSFVYTS 60
Query: 78 DPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASN 137
DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK AL G+ATDLF FIA +
Sbjct: 61 DPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPKSALVGDATDLFDFIAQS 120
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
VKK M APEDL + VPLGFTFSFPV+Q VN+G+LI+WTKGFSTK V+G+DV+ LLQA
Sbjct: 121 VKKMMSENAPEDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKGFSTKNVEGSDVVELLQA 180
Query: 198 AFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVA 257
+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSNACYFE ASAVTKDPAV+
Sbjct: 181 SLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSNACYFERASAVTKDPAVS 240
Query: 258 ARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARR 317
ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q EK++SGMYLGEI+RR
Sbjct: 241 ARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQRQEKLVSGMYLGEISRR 300
Query: 318 VIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+IVHL+ + CLP L L +FES+ GM++AD+MPGLQFTR I++V GVDV
Sbjct: 301 LIVHLAHLGCLPRGLVDGLCKPWAFESKHMGMVAADQMPGLQFTRELIKRVAGVDVTDTS 360
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNI 437
DL IR+ C LVR RAAQ + F AP++KT+TQG AT+A+DGSV+EK PSF+R+ Q+ I
Sbjct: 361 DLHTIREACCLVRNRAAQQGSVFTAAPMLKTRTQGLATVAVDGSVYEKTPSFQRLYQECI 420
Query: 438 NRILGPECDVRAVLAKDGSGIGAAFISAM 466
ILG + + VL KDGSG+GAA I A+
Sbjct: 421 TSILGSTSNAKVVLQKDGSGVGAAMICAL 449
>gb|AAV88622.1| hexokinase [Leishmania donovani]
Length = 434
Score = 546 bits (1406), Expect = e-153, Method: Composition-based stats.
Identities = 271/434 (62%), Positives = 341/434 (78%)
Query: 18 DGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKA 77
D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGLEGR STVRMLPS+VY +
Sbjct: 1 DSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGLEGRPSTVRMLPSFVYTS 60
Query: 78 DPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASN 137
DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK AL G+ATDLF FIA +
Sbjct: 61 DPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPKSALVGDATDLFDFIAQS 120
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKGFSTK V+GNDV+ LLQA
Sbjct: 121 VKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKGFSTKNVEGNDVVELLQA 180
Query: 198 AFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVA 257
+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSNACYFE ASAVTKDPAV+
Sbjct: 181 SLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSNACYFERASAVTKDPAVS 240
Query: 258 ARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARR 317
ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q EK++SGMYLGEI+RR
Sbjct: 241 ARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQRQEKLVSGMYLGEISRR 300
Query: 318 VIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+IVHL+ + CLP+ L L +FES+ GMI+AD+MPGLQFTR I+++ GVDV +
Sbjct: 301 LIVHLAQLGCLPSGLVDGLCRPWAFESKHMGMIAADQMPGLQFTRELIKRIAGVDVTDMS 360
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNI 437
DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DGSV+EK PSF+R+ Q+ I
Sbjct: 361 DLHTIRETCCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDGSVYEKTPSFQRLYQECI 420
Query: 438 NRILGPECDVRAVL 451
ILG +V+ VL
Sbjct: 421 TSILGSTSNVKVVL 434
>gb|AAV32969.1| hexokinase [Leishmania tropica]
Length = 387
Score = 493 bits (1269), Expect = e-137, Method: Composition-based stats.
Identities = 245/387 (63%), Positives = 303/387 (78%)
Query: 18 DGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKA 77
D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGLEGR STVRMLPS+VY +
Sbjct: 1 DSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGLEGRPSTVRMLPSFVYTS 60
Query: 78 DPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASN 137
DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK AL G+ATDLF FIA +
Sbjct: 61 DPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPKSALVGDATDLFDFIAQS 120
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKGFSTK V+GNDV+ LLQA
Sbjct: 121 VKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKGFSTKNVEGNDVVELLQA 180
Query: 198 AFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVA 257
+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSNACYFE ASAVTKDPAV+
Sbjct: 181 SLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSNACYFERASAVTKDPAVS 240
Query: 258 ARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARR 317
ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q EK++SGMYLGEI+RR
Sbjct: 241 ARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQRQEKLVSGMYLGEISRR 300
Query: 318 VIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQFTR I+++ GVDV +
Sbjct: 301 LIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQFTRELIKRIAGVDVTDMS 360
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAP 404
DL IR+ C LVR RAAQ A F AP
Sbjct: 361 DLHTIRETCCLVRNRAAQQGAVFAAAP 387
>gb|AAI00649.1| Hexokinase 3 [Rattus norvegicus]
gb|EDL94015.1| hexokinase 3, isoform CRA_a [Rattus norvegicus]
Length = 924
Score = 275 bits (704), Expect = 5e-72, Method: Composition-based stats.
Identities = 162/436 (37%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +S+E + + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 490 FQLSLEQLTAVQAQMREAMIRGLQGESSSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 549
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + + IP+Y +G+ LF I + + + +++PLG
Sbjct: 550 VLLVRVAEGSV-QITNQVYSIPEYVAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 606
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 607 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 666
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S INME G F
Sbjct: 667 GTMMSCGYDDPCCEMGLIVGTGTNACYMEELRNVASVPG----DSGHMCINMEWGAFGDD 722
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+ T FD +D AS+N G+Q EKMISGMYLGEI R +++HL+S+ L +T
Sbjct: 723 GSLSMLGTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQKTQC 782
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 783 LQTRDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 839
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F R++ + R L P+C V +
Sbjct: 840 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSVTV-RKLAPQCTVTFL 898
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 899 QSEDGSGKGAALVTAV 914
Score = 216 bits (550), Expect = 4e-54, Method: Composition-based stats.
Identities = 157/445 (35%), Positives = 232/445 (52%), Gaps = 26/445 (5%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF +++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 39 QFKVTMTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 98
Query: 93 -GTNFRVLRV---ACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPE 148
G + RVL V KE +V ++ + F IP+ + G LF F A + + ++ E
Sbjct: 99 TGASLRVLWVTLTGTKEHSV-ETRSQEFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE 157
Query: 149 DLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVN 207
N+ + LGF FSFP QT +++ LI WTKGF GV+G DV+ LL+ A R + ++
Sbjct: 158 --NQGLKLGFNFSFPCHQTGLDKSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYNID 215
Query: 208 VVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPIN 267
VVA+ NDTVGT++ +VG+I+ TG+NACY E A V A T ++
Sbjct: 216 VVAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVS 271
Query: 268 MESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINC 327
+E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHLS
Sbjct: 272 IEWGSFYDEEALGPVLTTFDDALDHESLVPGAQRFEKMIGGLYLGELVRLVLVHLSQHGV 331
Query: 328 LPAALQT-ALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVC 386
L + AL ++ S + D G+ + +Q + G+ Q+ D +++ VC
Sbjct: 332 LFGGCASPALLSQNSILLEHVAKME-DPATGIAHVHTVLQGL-GLSPQA-SDAELVQRVC 388
Query: 387 RLVRGRAAQLSASFCCAPLVKTQTQGR-----ATIAIDGSVFEKIPSFRRVLQDNINRIL 441
V RAAQL AS A L + Q +A G VFE P F +L++ + +L
Sbjct: 389 MAVCTRAAQLCASALAAVLSRLQHSREQQTLHVAVATGGRVFEWHPRFLCILKETV-MLL 447
Query: 442 GPECDVRAVLAKDGSGIGAAFISAM 466
PECDV + + DG G G A ++A+
Sbjct: 448 APECDVSFIPSVDGGGRGVAMVTAV 472
>gb|EDL94016.1| hexokinase 3, isoform CRA_b [Rattus norvegicus]
Length = 706
Score = 275 bits (702), Expect = 9e-72, Method: Composition-based stats.
Identities = 162/436 (37%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +S+E + + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 272 FQLSLEQLTAVQAQMREAMIRGLQGESSSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 331
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + + IP+Y +G+ LF I + + + +++PLG
Sbjct: 332 VLLVRVAEGSV-QITNQVYSIPEYVAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 388
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 389 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 448
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S INME G F
Sbjct: 449 GTMMSCGYDDPCCEMGLIVGTGTNACYMEELRNVASVPG----DSGHMCINMEWGAFGDD 504
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+ T FD +D AS+N G+Q EKMISGMYLGEI R +++HL+S+ L +T
Sbjct: 505 GSLSMLGTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQKTQC 564
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 565 LQTRDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 621
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F R++ + R L P+C V +
Sbjct: 622 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSVTV-RKLAPQCTVTFL 680
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 681 QSEDGSGKGAALVTAV 696
Score = 116 bits (290), Expect = 4e-24, Method: Composition-based stats.
Identities = 90/263 (34%), Positives = 127/263 (48%), Gaps = 16/263 (6%)
Query: 211 LCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMES 270
+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++E
Sbjct: 1 MVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSIEW 56
Query: 271 GNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL-- 328
G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHLS L
Sbjct: 57 GSFYDEEALGPVLTTFDDALDHESLVPGAQRFEKMIGGLYLGELVRLVLVHLSQHGVLFG 116
Query: 329 PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRL 388
A L A M D G+ + +Q + G+ Q+ D +++ VC
Sbjct: 117 GCASPALLSQNSILLEHVAKM--EDPATGIAHVHTVLQGL-GLSPQA-SDAELVQRVCMA 172
Query: 389 VRGRAAQLSASFCCAPLVKTQTQGR-----ATIAIDGSVFEKIPSFRRVLQDNINRILGP 443
V RAAQL AS A L + Q +A G VFE P F +L++ + +L P
Sbjct: 173 VCTRAAQLCASALAAVLSRLQHSREQQTLHVAVATGGRVFEWHPRFLCILKETV-MLLAP 231
Query: 444 ECDVRAVLAKDGSGIGAAFISAM 466
ECDV + + DG G G A ++A+
Sbjct: 232 ECDVSFIPSVDGGGRGVAMVTAV 254
>ref|NP_071515.1| hexokinase 3 [Rattus norvegicus]
sp|P27926|HXK3_RAT Hexokinase-3 (Hexokinase type III) (HK III)
gb|AAB18253.1| hexokinase type III [Rattus norvegicus]
Length = 924
Score = 273 bits (699), Expect = 2e-71, Method: Composition-based stats.
Identities = 161/434 (37%), Positives = 253/434 (58%), Gaps = 18/434 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +S+E + + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 490 FQLSLEQLTAVQAQMREAMIRGLQGESSSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 549
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + + IP+Y +G+ LF I + + + +++PLG
Sbjct: 550 VLLVRVAEGSV-QITNQVYSIPEYVAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 606
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 607 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 666
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S INME G F
Sbjct: 667 GTMMSCGYDDPCCEMGLIVGTGTNACYMEELRNVASVPG----DSGHMCINMEWGAFGDD 722
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+ T FD +D AS+N G+Q EKMISGMYLGEI R +++HL+S+ L +T
Sbjct: 723 GSLSMLGTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQKTQC 782
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 783 LQTRDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 839
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F R++ + R L P+C V +
Sbjct: 840 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSVTV-RKLAPQCTVTFL 898
Query: 451 LAKDGSGIGAAFIS 464
++DGSG GAA ++
Sbjct: 899 QSEDGSGKGAALVT 912
Score = 216 bits (550), Expect = 4e-54, Method: Composition-based stats.
Identities = 157/445 (35%), Positives = 232/445 (52%), Gaps = 26/445 (5%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF +++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 39 QFKVTMTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 98
Query: 93 -GTNFRVLRV---ACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPE 148
G + RVL V KE +V ++ + F IP+ + G LF F A + + ++ E
Sbjct: 99 TGASLRVLWVTLTGTKEHSV-ETRSQEFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE 157
Query: 149 DLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVN 207
N+ + LGF FSFP QT +++ LI WTKGF GV+G DV+ LL+ A R + ++
Sbjct: 158 --NQGLKLGFNFSFPCHQTGLDKSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYNID 215
Query: 208 VVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPIN 267
VVA+ NDTVGT++ +VG+I+ TG+NACY E A V A T ++
Sbjct: 216 VVAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVS 271
Query: 268 MESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINC 327
+E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHLS
Sbjct: 272 IEWGSFYDEEALGPVLTTFDDALDHESLVPGAQRFEKMIGGLYLGELVRLVLVHLSQHGV 331
Query: 328 LPAALQT-ALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVC 386
L + AL ++ S + D G+ + +Q + G+ Q+ D +++ VC
Sbjct: 332 LFGGCASPALLSQNSILLEHVAKME-DPATGIAHVHTVLQGL-GLSPQA-SDAELVQRVC 388
Query: 387 RLVRGRAAQLSASFCCAPLVKTQTQGR-----ATIAIDGSVFEKIPSFRRVLQDNINRIL 441
V RAAQL AS A L + Q +A G VFE P F +L++ + +L
Sbjct: 389 MAVCTRAAQLCASALAAVLSRLQHSREQQTLHVAVATGGRVFEWHPRFLCILKETV-MLL 447
Query: 442 GPECDVRAVLAKDGSGIGAAFISAM 466
PECDV + + DG G G A ++A+
Sbjct: 448 APECDVSFIPSVDGGGRGVAMVTAV 472
>dbj|BAE24390.1| unnamed protein product [Mus musculus]
dbj|BAE37444.1| unnamed protein product [Mus musculus]
Length = 922
Score = 271 bits (692), Expect = 1e-70, Method: Composition-based stats.
Identities = 160/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E M + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQMTVVQAQMRVAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 897 QSEDGSGKGAALVTAV 912
Score = 198 bits (504), Expect = 7e-49, Method: Composition-based stats.
Identities = 156/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ + +L P CDV + + DG G G A ++A+
Sbjct: 437 ILKETVT-LLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>ref|NP_001028417.1| hexokinase 3 [Mus musculus]
sp|Q3TRM8|HXK3_MOUSE Hexokinase-3 (Hexokinase type III) (HK III)
dbj|BAE42538.1| unnamed protein product [Mus musculus]
dbj|BAE32706.1| unnamed protein product [Mus musculus]
Length = 922
Score = 270 bits (691), Expect = 1e-70, Method: Composition-based stats.
Identities = 160/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E M + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQMTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 897 QSEDGSGKGAALVTAV 912
Score = 198 bits (504), Expect = 7e-49, Method: Composition-based stats.
Identities = 156/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ + +L P CDV + + DG G G A ++A+
Sbjct: 437 ILKETVT-LLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>dbj|BAE37000.1| unnamed protein product [Mus musculus]
Length = 922
Score = 270 bits (691), Expect = 1e-70, Method: Composition-based stats.
Identities = 160/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E M + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQMTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 897 QSEDGSGKGAALVTAV 912
Score = 197 bits (501), Expect = 1e-48, Method: Composition-based stats.
Identities = 155/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ + R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDSIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ + +L P CDV + + DG G G A ++A+
Sbjct: 437 ILKETVT-LLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>dbj|BAE29220.1| unnamed protein product [Mus musculus]
Length = 922
Score = 270 bits (691), Expect = 1e-70, Method: Composition-based stats.
Identities = 160/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E M + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQMTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 897 QSEDGSGKGAALVTAV 912
Score = 198 bits (504), Expect = 6e-49, Method: Composition-based stats.
Identities = 156/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQCVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ + +L P CDV + + DG G G A ++A+
Sbjct: 437 ILEETVT-LLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>ref|XP_546212.2| PREDICTED: similar to Hexokinase type III (HK III) [Canis
familiaris]
Length = 957
Score = 270 bits (690), Expect = 2e-70, Method: Composition-based stats.
Identities = 165/437 (37%), Positives = 252/437 (57%), Gaps = 20/437 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F ++ E + + + MV+GL G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 519 FQLNHEQLAAVQAQMREAMVKGLRGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 578
Query: 98 VLRV-ACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPL 156
VL V EG V + + IP+ +G+ LF I + + + +++PL
Sbjct: 579 VLLVRVTAEG--VKITNQIYSIPENVAQGSGQQLFDHIVDCIVDFQQKQGLS--GQSLPL 634
Query: 157 GFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDT 215
GFTFSFP Q +++G+L+ WTKGFS +G D++ LL+ A GR ++++NVVA+ NDT
Sbjct: 635 GFTFSFPCRQLGLDQGILLNWTKGFSASDCEGQDIVCLLREAIGRRQAVELNVVAIVNDT 694
Query: 216 VGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDS 275
VGT++S ++DP +VG+I+GTG+NACY E V A A S INME G F
Sbjct: 695 VGTMMSCGYEDPRCEVGLIVGTGTNACYMEELRNV----AAVAGDSGQMCINMEWGAFGD 750
Query: 276 KYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQTA 335
L T FD +D AS+N G+Q+ EKMISGMYLGEI R +++HL+S+ L QT
Sbjct: 751 DGSLGLLRTCFDASVDQASINPGKQSFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQTQ 810
Query: 336 -LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAA 394
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAA
Sbjct: 811 RLQTRDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLSLTS-DDALMVLEVCQAVSQRAA 867
Query: 395 QLSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRA 449
QL + A + K + + +I +DG++++ P F ++ + R L P C V
Sbjct: 868 QLCGAGVAAVVEKIRENRGLEELTVSIGVDGTLYKLHPHFSSLVAATV-RELAPRCVVTF 926
Query: 450 VLAKDGSGIGAAFISAM 466
+ ++DGSG GAA ++A+
Sbjct: 927 LQSEDGSGKGAALVTAV 943
Score = 192 bits (487), Expect = 6e-47, Method: Composition-based stats.
Identities = 157/444 (35%), Positives = 229/444 (51%), Gaps = 24/444 (5%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L G+ S VRMLP+YV G F L+LG
Sbjct: 68 QFKVTGTQLQQIQASLLDSMEQALGGQASPASAVRMLPTYVGSIPHGTEQGDFVVLELGA 127
Query: 93 -GTNFRVLRVAC--KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V G ++ + F IP + G LF F A + + ++ A
Sbjct: 128 TGASLRVLWVTLMGTGGHRMEPRSQEFVIPPEVMLGPGQQLFDFAAHCLSEFLD--ALPV 185
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
+ + LGF+FSFP QT ++R LI WTKGF GV+G+DV+ LL+ A R + ++V
Sbjct: 186 GKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGHDVVQLLRDAIKRHGAYNIDV 245
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+++ TG+NACY E A V AV +++
Sbjct: 246 VAVVNDTVGTMMGCEPGVGPCEVGLVVDTGTNACYMEEARHV----AVLDEDRGRVCVSV 301
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F T FD +D SLN G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 302 EWGSFGDDGVLGPMLTIFDHALDRESLNPGAQRFEKMIGGLYLGELVRLVLVHLAQRGVL 361
Query: 329 PAALQT-ALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCR 387
+ AL +RGS + D G + +Q + G++V + D+ +++ VC
Sbjct: 362 FGGCTSPALLSRGSILLEHVAEME-DPWAGAARVHALLQDL-GLNVGA-SDVELVQYVCA 418
Query: 388 LVRGRAAQLSASFCCAPLVKTQTQGRATI-----AIDGSVFEKIPSFRRVLQDNINRILG 442
V RAA+L A+ A L + Q I A G VFE+ PSF +LQ+ + +L
Sbjct: 419 AVFTRAARLCAAALAAVLSRLQHSREQQILQIAVATGGRVFEQHPSFLSILQETV-MLLT 477
Query: 443 PECDVRAVLAKDGSGIGAAFISAM 466
PECDV + + DG G G A ++A+
Sbjct: 478 PECDVSFIPSVDGGGRGVAMVTAV 501
>gb|AAI17862.1| Hk3 protein [Mus musculus]
Length = 877
Score = 270 bits (689), Expect = 3e-70, Method: Composition-based stats.
Identities = 159/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E + + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 443 FQLTLEQLTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 502
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 503 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 559
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 560 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 619
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 620 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 675
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 676 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 735
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 736 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 792
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 793 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 851
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 852 QSEDGSGKGAALVTAV 867
Score = 175 bits (444), Expect = 6e-42, Method: Composition-based stats.
Identities = 145/426 (34%), Positives = 214/426 (50%), Gaps = 47/426 (11%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P RR
Sbjct: 377 SDAELVQCVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHP--RR 434
Query: 432 VLQDNI 437
+L++ +
Sbjct: 435 ILEETL 440
>dbj|BAE42341.1| unnamed protein product [Mus musculus]
dbj|BAE42318.1| unnamed protein product [Mus musculus]
Length = 922
Score = 269 bits (687), Expect = 4e-70, Method: Composition-based stats.
Identities = 159/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E + + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQLTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 897 QSEDGSGKGAALVTAV 912
Score = 198 bits (504), Expect = 7e-49, Method: Composition-based stats.
Identities = 156/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ + +L P CDV + + DG G G A ++A+
Sbjct: 437 ILKETVT-LLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>ref|XP_001498596.1| PREDICTED: similar to Hexokinase 3 (white cell) [Equus caballus]
Length = 984
Score = 269 bits (687), Expect = 4e-70, Method: Composition-based stats.
Identities = 164/437 (37%), Positives = 254/437 (58%), Gaps = 20/437 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +S E + + + M++GL G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 550 FRLSQEQLAALQAQMREAMIKGLRGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 609
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLN-RTVPL 156
VL V G V + + IP+ +G+ LF I + M+ + + L+ +++PL
Sbjct: 610 VLLVRVATGGV-QITNQVYSIPECVAQGSGQQLFDHIVDCI---MDFQQKQGLSGQSLPL 665
Query: 157 GFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDT 215
GFTFSFP Q +++G+L+ WTKGF+ +G DV+ LL+ A GR +++NVVA+ NDT
Sbjct: 666 GFTFSFPCRQLGLDQGILLNWTKGFNASDCEGQDVVCLLREAIGRRKGVELNVVAIVNDT 725
Query: 216 VGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDS 275
VGT++S ++DP +VG+I+GTG+NACY E V A A S INME G F
Sbjct: 726 VGTMMSCGYEDPHCEVGLIVGTGTNACYMEELENV----AGVAGDSGHMCINMEWGAFGD 781
Query: 276 KYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT- 334
+ +T FD +D AS+N G+Q EKMISGMYLGEI R +++HL+S+ L QT
Sbjct: 782 DGSLDVLSTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQTQ 841
Query: 335 ALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAA 394
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAA
Sbjct: 842 CLQTRDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLPLTS-DDALMVLEVCQAVSQRAA 898
Query: 395 QLSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRA 449
QL + A + K + + ++ +DG++++ P F ++ + R L P C V
Sbjct: 899 QLCGAGVAAVVEKIRENRGLEELTVSVGVDGTLYKLHPHFSSMVAATV-RKLAPRCVVTF 957
Query: 450 VLAKDGSGIGAAFISAM 466
+ ++DGSG GAA ++A+
Sbjct: 958 LQSEDGSGKGAALVTAV 974
Score = 202 bits (515), Expect = 4e-50, Method: Composition-based stats.
Identities = 158/445 (35%), Positives = 227/445 (51%), Gaps = 26/445 (5%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L G+ S VRMLP+YV G F L+LG
Sbjct: 99 QFKVTGAQLQQIQASLLGSMEQALGGQTSPAPAVRMLPTYVGSTPHGTEQGDFVVLELGA 158
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + R+L V EG ++ + F IP+ + G LF F A + + ++T
Sbjct: 159 TGASLRILWVTLTGIEGHRIEPRSQEFVIPQEVMLGPGQQLFDFAARCLSEFLDTLPVG- 217
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + ++V
Sbjct: 218 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLREAIQRQGAYSIDV 276
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V AV I++
Sbjct: 277 VAVVNDTVGTMMGCEPGVGPCEVGLIVDTGTNACYMEEARHV----AVLDEDRGRVCISV 332
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F T FD +D SLN G Q EKMI G+YLGE+ R V+ HL+ L
Sbjct: 333 EWGSFSDDGALGPVLTIFDCALDQESLNPGAQRFEKMIGGLYLGELVRLVLAHLAQCGVL 392
Query: 329 PAALQT-ALGNRGSFESRFAGMISADRMPGLQFTR-STIQKVCGVDVQSIEDLRIIRDVC 386
+ AL +RGS ++ P + R TI + G+ D ++++DVC
Sbjct: 393 FGGCASPALLSRGSI---LLEHVAEMEDPSVGAARVHTILQDLGLS-PGASDAKLVQDVC 448
Query: 387 RLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRIL 441
V RAAQL A+ A L + Q + +A G VFE+ P F +LQ+ + L
Sbjct: 449 AAVCTRAAQLCAAALAAVLSRLQHSREQQTLQIAVATGGRVFERHPRFLSILQETV-MFL 507
Query: 442 GPECDVRAVLAKDGSGIGAAFISAM 466
P+CDV + + DG G G A ++A+
Sbjct: 508 APKCDVSFIPSLDGGGRGVAMVTAV 532
>dbj|BAE42045.1| unnamed protein product [Mus musculus]
Length = 867
Score = 268 bits (686), Expect = 6e-70, Method: Composition-based stats.
Identities = 159/436 (36%), Positives = 255/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E + + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 433 FQLTLEQLTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 492
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 493 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 549
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 550 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 609
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 610 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 665
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 666 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 725
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 726 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 782
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 783 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 841
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 842 QSEDGSGKGAALVTAV 857
Score = 184 bits (468), Expect = 1e-44, Method: Composition-based stats.
Identities = 149/436 (34%), Positives = 220/436 (50%), Gaps = 46/436 (10%)
Query: 56 MVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG--GTNFRVLRVACK--EGAV 108
M + L+G++S +VRMLP+YV G F L+LG G + RVL V +
Sbjct: 1 MEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTKECR 60
Query: 109 VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTK 168
V+ + F IP+ + G LF F A + + ++ E N+ + LGF FSFP QT
Sbjct: 61 VEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE--NQGLKLGFNFSFPCHQTG 118
Query: 169 VNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNVVALCNDTVGTLISHYFKDP 227
++R LI WTKGF GV+G DV+ LL+ A R + +++VVA+ NDTVGT++
Sbjct: 119 LDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDVVAMVNDTVGTMMGCELGTR 178
Query: 228 EVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFD 287
+V +I+ TG+NACY E A V A T +++E G+F + T FD
Sbjct: 179 PCEVRLIVDTGTNACYMEEARHV----AALDEDRGRTCVSIEWGSFYDEDALGPVLTTFD 234
Query: 288 LDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL------PAALQTALGNRGS 341
+D SL G Q EKMI G+YLGE+ R V+VHL+ L PA L
Sbjct: 235 SALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVLFDGCASPALLSQ------- 287
Query: 342 FESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
G I D + ++ T + TI + G+ ++ D +++ VC V RAAQ
Sbjct: 288 ------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA-SDAELVQYVCVAVCTRAAQ 340
Query: 396 LSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L A+ A L + Q + +A G VFE+ P F R+L++ + +L P CDV +
Sbjct: 341 LCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLRILKETVT-LLAPNCDVSFI 399
Query: 451 LAKDGSGIGAAFISAM 466
+ DG G G A ++A+
Sbjct: 400 PSVDGGGRGVAMVTAV 415
>ref|XP_453567.1| HXK_KLULA [Kluyveromyces lactis]
sp|P33284|HXK_KLULA Hexokinase
emb|CAH00663.1| HXK_KLULA [Kluyveromyces lactis NRRL Y-1140]
Length = 485
Score = 268 bits (685), Expect = 7e-70, Method: Composition-based stats.
Identities = 158/444 (35%), Positives = 249/444 (56%), Gaps = 13/444 (2%)
Query: 33 ALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLG 92
L FT+S E MR I+ + + E+ +GL + + M+P +V + + TG F ALDLG
Sbjct: 29 GLETLFTVSSEKMRSIVKHFISELDKGLSKKGGNIPMIPGWVVEYPTGKETGDFLALDLG 88
Query: 93 GTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNR 152
GTN RV+ V D++ + +++P + G + L+ FIA +K+ ++ P+ ++
Sbjct: 89 GTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSE 148
Query: 153 TVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVVALC 212
+PLGFTFS+P Q K+N GVL RWTKGF +GV+G+DV+ +LQ ++++ +NVVAL
Sbjct: 149 PLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLNIPINVVALI 208
Query: 213 NDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARG---SALTPINME 269
NDT GTL++ + DP+ ++G+IIGTG N Y++ S + K + + IN E
Sbjct: 209 NDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCE 268
Query: 270 SGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHL-SSINCL 328
G+FD+++ VLP TK+D+ ID+ S GQQA EKM SG YLGEI R V++ L S
Sbjct: 269 YGSFDNEH-LVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIF 327
Query: 329 PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRL 388
+ L ++ + I D L+ T + ++ +E ++IR + L
Sbjct: 328 KDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVER-KLIRKLAEL 386
Query: 389 VRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR----RVLQDNINRILGPE 444
V RAA+L+ A + + A IA DGSVF + P ++ + L+D N +
Sbjct: 387 VGTRAARLTVCGVSA-ICDKRGYKTAHIAADGSVFNRYPGYKEKAAQALKDIYNWDVEKM 445
Query: 445 CD--VRAVLAKDGSGIGAAFISAM 466
D ++ V A+DGSG+GAA I+ +
Sbjct: 446 EDHPIQLVAAEDGSGVGAAIIACL 469
>sp|Q9SEK3|HXK1_SPIOL Hexokinase-1 (SoHxK1)
gb|AAF18584.1|AF118132_1 chloroplast outer envelope hexokinase 1 [Spinacia oleracea]
Length = 498
Score = 268 bits (685), Expect = 8e-70, Method: Composition-based stats.
Identities = 178/442 (40%), Positives = 243/442 (54%), Gaps = 30/442 (6%)
Query: 45 MRQIMTYLLYEMVEGLEGR-ESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVAC 103
+RQ+ + EM GL S ++ML SYV G+FYALDLGGTNFRVLRV
Sbjct: 55 LRQVADAMTVEMHAGLASEGASKLKMLISYVDNLPTGDEHGLFYALDLGGTNFRVLRVKL 114
Query: 104 --KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRA----PEDLNRTVPLG 157
KE VV+ IP + G + LF +IA + K + T + PE N+ LG
Sbjct: 115 GGKEKRVVEQEFDEVSIPPELMVGTSEQLFDYIAEALAKFVATESEGLHPEP-NKQRELG 173
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVG 217
FTFSFPV+QT + G LIRWTKGF+ + G DV+A L A R + + V AL NDTVG
Sbjct: 174 FTFSFPVKQTSIASGTLIRWTKGFNIEDTVGEDVVAELTKAMLRKGVDMRVTALVNDTVG 233
Query: 218 TLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKY 277
TL + +V VI+GTG+NA Y E ASA+ K + + INME GNF S Y
Sbjct: 234 TLAGGRYYKEDVIAAVILGTGTNAAYVERASAIHKWHGPLPKSGEMV-INMEWGNFRSSY 292
Query: 278 RFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL-----PAAL 332
LP T++D+ +D+ SLN G+Q EKMISGMYLGEI RRV+ ++ L P+ L
Sbjct: 293 ---LPLTEYDIALDEESLNPGEQIFEKMISGMYLGEIVRRVLYRMADEASLFGDTVPSKL 349
Query: 333 QTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGR 392
+T R S + D P L+ S ++ V G+ S++ +II DVC ++ R
Sbjct: 350 KTPFILRTPDMS----AMHHDTSPDLKVVASKLKDVLGIPNSSLKVRKIIVDVCDVIASR 405
Query: 393 AAQLSASFCCAPLVK----TQTQG---RATIAIDGSVFEKIPSFRRVLQDNINRILGPEC 445
A +SA+ + K T QG ++ IA+DG +FE FR ++D++ +LG E
Sbjct: 406 GACISAAGILGIIKKLGRDTLKQGENQKSVIALDGGLFEHYAKFRECMEDSLKELLGDEV 465
Query: 446 DVRAVL--AKDGSGIGAAFISA 465
V+ + DGSGIGAA ++A
Sbjct: 466 AETIVIEHSNDGSGIGAALLAA 487
>ref|XP_001525198.1| hexokinase [Lodderomyces elongisporus NRRL YB-4239]
gb|EDK44947.1| hexokinase [Lodderomyces elongisporus NRRL YB-4239]
Length = 485
Score = 268 bits (684), Expect = 8e-70, Method: Composition-based stats.
Identities = 158/443 (35%), Positives = 249/443 (56%), Gaps = 13/443 (2%)
Query: 34 LTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGG 93
L QFT+S E++R+I+ + + E+ +GL + M+P +V + TG + A+DLGG
Sbjct: 30 LEKQFTVSGETLRKIVDHFITELDKGLSKAGGNIPMIPGWVMDFPTGKETGDYLAIDLGG 89
Query: 94 TNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRT 153
TN RV+ V D++ S F +P + +L+ FIA+ +K E P +
Sbjct: 90 TNLRVVLVKLGGNRDFDTTQSKFPLPSNMRTATSEELWSFIANCLKTFFEEEFPNGVEEP 149
Query: 154 VPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVVALCN 213
+PLGFTFS+P Q + +GVL RWTKG++ +GV+G+DV+ +LQ+A +V + V +VA+ N
Sbjct: 150 LPLGFTFSYPASQNTITQGVLQRWTKGWAIEGVEGHDVVPMLQSAIEKVQVPVKIVAVIN 209
Query: 214 DTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTK-DPAVAARGSALTP--INMES 270
DTVGTL++ + DPE ++G+I GTG N Y++ + K + + + +P IN E
Sbjct: 210 DTVGTLVASNYTDPEAKLGLIFGTGVNGAYYDVVGDIPKLEGKLESDIGVDSPMAINCEY 269
Query: 271 GNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPA 330
G+FD++ +F+LP K+D+ ID+ S GQQ EKM SG YLGEI R V+V L+ +
Sbjct: 270 GSFDNE-KFILPRNKYDVMIDEESPRPGQQTFEKMNSGYYLGEILRLVLVDLAENKKVIF 328
Query: 331 ALQ--TALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRL 388
Q T L ++ F I D L + Q V G++ ++ + ++IR + L
Sbjct: 329 KNQDLTKLNEVYILDTSFPAKIEEDPFENLSDVQEIFQSVLGLET-TVPERKVIRRIAEL 387
Query: 389 VRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVR 448
+ R+A+LS A + K + A A DGSV+ K P F++ ++ I DV+
Sbjct: 388 IGNRSARLSVC-GIAAICKKRGYKTAHCAADGSVYSKYPDFKQRAAQSLRDIFEWSDDVK 446
Query: 449 A-----VLAKDGSGIGAAFISAM 466
V A+DGSG+GAA I+A+
Sbjct: 447 EDPILIVDAEDGSGVGAAIIAAL 469
>dbj|BAE35470.1| unnamed protein product [Mus musculus]
dbj|BAE35564.1| unnamed protein product [Mus musculus]
dbj|BAE35599.1| unnamed protein product [Mus musculus]
Length = 922
Score = 268 bits (684), Expect = 1e-69, Method: Composition-based stats.
Identities = 159/436 (36%), Positives = 254/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E M + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQMTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGS GAA ++A+
Sbjct: 897 QSEDGSDKGAALVTAV 912
Score = 198 bits (504), Expect = 7e-49, Method: Composition-based stats.
Identities = 156/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ + +L P CDV + + DG G G A ++A+
Sbjct: 437 ILKETVT-LLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>ref|NP_985826.1| AFR279Cp [Ashbya gossypii ATCC 10895]
gb|AAS53650.1| AFR279Cp [Ashbya gossypii ATCC 10895]
Length = 488
Score = 267 bits (683), Expect = 1e-69, Method: Composition-based stats.
Identities = 165/454 (36%), Positives = 252/454 (55%), Gaps = 28/454 (6%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALD 90
+A+ FT+S E +++I + + E+ +GL + + M+P +V TG + A+D
Sbjct: 27 IASFERIFTVSAEKLQEITKHFVTELDKGLSKKGGNIPMIPGWVMDYPTGNETGDYLAID 86
Query: 91 LGGTNFRVLRVACKEGAVVDSSTSAFKIP-KYALEGNATDLFGFIASNVKKTMETRAPED 149
LGGTN RV+ V D++ S +++P + NA++L+ FIA ++K +E + PE
Sbjct: 87 LGGTNLRVVLVKLLGNHQFDTTQSKYRLPNRMRTTQNASELWDFIAESLKDFLEEQFPEG 146
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVV 209
+++T+PLGFTFS+P Q K+N G+L RWTKGF GV+G+DV+ +LQ + +V++ + VV
Sbjct: 147 VHQTLPLGFTFSYPASQDKINMGILQRWTKGFDIPGVEGHDVVPMLQESLRKVNVPIEVV 206
Query: 210 ALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTK----DPAVAARGSALTP 265
AL NDT GTL++ + D E ++GVI GTG N Y++ + K P SA+
Sbjct: 207 ALINDTTGTLVASLYTDAETKMGVIFGTGVNGAYYDVVKDIEKLEGRLPEDIPPESAMA- 265
Query: 266 INMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSI 325
IN E G+FD+++ VLP TK+D+ ID+ S GQQA EKM SG YLGE+ R ++ L
Sbjct: 266 INCEYGSFDNEH-LVLPRTKYDILIDEQSPRPGQQAFEKMTSGYYLGEVLRLALLDLHGQ 324
Query: 326 NCL-----PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLR 380
+ + L+T SF +R I D L+ T + +D E +
Sbjct: 325 GLIFQGQDISKLETPYVMDTSFPAR----IEDDPFENLEETDDLFKDNLDIDTTRPER-K 379
Query: 381 IIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRAT--IAIDGSVFEKIPSFRRVLQDNIN 438
+IR + ++ RAA+LS C Q +G T IA DGSVF K P F+ + +
Sbjct: 380 LIRKLSEMIGNRAARLSV---CGIAAICQKRGYETAHIAADGSVFNKYPGFQTRAAEGLR 436
Query: 439 RILGPECD------VRAVLAKDGSGIGAAFISAM 466
I G E ++ V A+DGSG GAA I+A+
Sbjct: 437 DIYGWEHSSSQDYPIKIVAAEDGSGAGAAVIAAL 470
>dbj|BAE29007.1| unnamed protein product [Mus musculus]
Length = 922
Score = 267 bits (682), Expect = 1e-69, Method: Composition-based stats.
Identities = 159/436 (36%), Positives = 254/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E M + + M+ L+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQMTVVQAQMREAMIRELQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+T+FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSTRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELAVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 897 QSEDGSGKGAALVTAV 912
Score = 199 bits (506), Expect = 5e-49, Method: Composition-based stats.
Identities = 157/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQYVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ I +L P CDV + + DG G G A ++A+
Sbjct: 437 ILKETIT-LLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>emb|CAG09720.1| unnamed protein product [Tetraodon nigroviridis]
Length = 894
Score = 267 bits (682), Expect = 1e-69, Method: Composition-based stats.
Identities = 162/456 (35%), Positives = 251/456 (55%), Gaps = 21/456 (4%)
Query: 23 RAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLE---GRESTVRMLPSYVYKADP 79
R + A+ + +S E + ++ + M+EGL ++S+V+MLP+YV
Sbjct: 443 RCAAQQAERQAILDTLRLSREQLLEVKNRMRGSMLEGLSEHTHKDSSVKMLPTYVRSTPD 502
Query: 80 KRATGVFYALDLGGTNFRVLRVACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASN 137
G F A+DLGG+NFRVL V + G V+ + IP+ L+G +LF I
Sbjct: 503 GTEQGDFLAVDLGGSNFRVLLVQIQSGTKRSVNLHQKIYHIPQETLQGTGEELFDHIVQC 562
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
+ +E ++PLGFTFSFP Q+++++G+L+RWTKGF G +G DVI LL+
Sbjct: 563 MASFLEYMGLS--GASLPLGFTFSFPCHQSRLDQGILLRWTKGFKASGCEGRDVIMLLKE 620
Query: 198 AFG-RVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAV 256
A R +N VA+ NDTVGT+++ ++DP +VG+I+GTG+N CY E +
Sbjct: 621 AVNRRKEFDLNFVAVVNDTVGTMMTCGYEDPRCEVGLIVGTGTNVCYMEEVGNMDLVDGD 680
Query: 257 AARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIAR 316
R +NME G F +T+FD +DD S N G+Q EKMISGMYLGEI R
Sbjct: 681 EGR----MCVNMEWGAFGDAGELDDFSTQFDRLVDDCSTNPGKQRYEKMISGMYLGEIVR 736
Query: 317 RVIVHLSSINCL-PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQS 375
V++H + L L L RG F ++F I +DR+ ++ RS +Q + G+ +
Sbjct: 737 NVLMHFTDRGLLFRGKLSERLKMRGIFATKFLAQIESDRL-AMRQVRSILQHL-GLTNST 794
Query: 376 IEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFR 430
+D ++++VC +V RAAQL + A + K + Q T+ +DG++++ P F
Sbjct: 795 CDDSVLVKEVCSVVSRRAAQLCGAGLAAVVDKMRENRNLNQLSVTVGVDGTLYKTHPHFS 854
Query: 431 RVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
R++Q+ + L P+C V ++DGSG GAA I+A+
Sbjct: 855 RIMQETLQD-LAPQCQVTFHKSEDGSGKGAALITAV 889
Score = 236 bits (602), Expect = 3e-60, Method: Composition-based stats.
Identities = 158/445 (35%), Positives = 239/445 (53%), Gaps = 24/445 (5%)
Query: 36 NQFTMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKRATGVFYALDLG 92
++F +S E + +I EM +GL + VRMLP++V G F ALDLG
Sbjct: 6 HRFQLSHEDLMEISVRFRREMDKGLCRDTSPTAAVRMLPTFVRSTPDGTEHGEFLALDLG 65
Query: 93 GTNFRVL--RVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDL 150
G+NFRVL +V V+ + IP++ ++G+ T+LF IA + ME ++
Sbjct: 66 GSNFRVLLVKVMADGEQKVEMENQVYAIPEHLMKGSGTELFDHIADCLANFMEKMGIKE- 124
Query: 151 NRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAF-GRVSLKVNVV 209
+ +PLGFTFSFP +QTK++ VL+ WTK F + GV+G DV+ LL+ + R +V+
Sbjct: 125 -KKLPLGFTFSFPCQQTKLDESVLLSWTKAFKSSGVEGKDVVELLRKSIKKRGDFDADVM 183
Query: 210 ALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINME 269
A+ NDTVGT+++ + D ++G+I+GTG+NACY E ++ V +N E
Sbjct: 184 AVINDTVGTMMTCGYDDHLCEIGLIVGTGTNACYMEQ----MRNIEVLEGDEGRMCVNTE 239
Query: 270 SGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP 329
G F T D +ID SLN G+Q EKM+SG+YLGE+ R ++V ++ L
Sbjct: 240 WGAFGDDGALEDLRTDLDREIDAGSLNPGRQLFEKMVSGLYLGELVRLILVKMAKEQLLF 299
Query: 330 AALQTA-LGNRGSFESRFAGMISADR-MPGLQFTRSTIQKVCGVDVQ-SIEDLRIIRDVC 386
TA L GSF++ I D GL ++ G+ + + ED +R VC
Sbjct: 300 QGKSTAELLTTGSFKTSHICTIDVDNDEEGLASAEKVLR---GLKISPTSEDCAAVRRVC 356
Query: 387 RLVRGRAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRIL 441
++V R+A L A+ A L K + R TI +DGSV++ F R L + R L
Sbjct: 357 QIVSTRSAHLCAATLVAILRQIRDNKAAEKLRTTIGVDGSVYKSHQEFSRRLHKMV-RQL 415
Query: 442 GPECDVRAVLAKDGSGIGAAFISAM 466
P+CDVR + ++ GSG GAA ++A+
Sbjct: 416 VPDCDVRFLQSQCGSGKGAAMVTAV 440
>gb|AAI17861.1| Hk3 protein [Mus musculus]
Length = 922
Score = 267 bits (682), Expect = 2e-69, Method: Composition-based stats.
Identities = 158/436 (36%), Positives = 254/436 (58%), Gaps = 18/436 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F +++E + + + M+ GL+G S++RMLP+YV G F ALDLGGTNFR
Sbjct: 488 FQLTLEQLTVVQAQMREAMIRGLQGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFR 547
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLG 157
VL V EG+V + IP+ +G+ LF I + + + +++PLG
Sbjct: 548 VLLVRVAEGSV-QIINQVYSIPECRAQGSGQKLFDHIVDCIVDFQKRQGLS--GQSLPLG 604
Query: 158 FTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDTV 216
FTFSFP +Q +++G+L+ WTKGF+ G +G DV+ LL+ A R ++++NVVA+ NDTV
Sbjct: 605 FTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTV 664
Query: 217 GTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSK 276
GT++S + DP ++G+I+GTG+NACY E V P S L INME G F
Sbjct: 665 GTMMSCGYDDPRCEMGLIVGTGTNACYMEELRNVASVPG----DSGLMCINMEWGAFGDD 720
Query: 277 YRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQT-A 335
+ +FD +D AS+N G+Q EKMISGMYLGEI R +++HL+++ L +T
Sbjct: 721 GSLGTLSPRFDTSVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTNLGVLFRGQKTQC 780
Query: 336 LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQ 395
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAAQ
Sbjct: 781 LQARDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLTLTS-DDALMVLEVCQAVSRRAAQ 837
Query: 396 LSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAV 450
L + A + K + + ++ +DG++++ P F +++ + R L P+C V +
Sbjct: 838 LCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSKLVSATV-RKLAPQCTVTFL 896
Query: 451 LAKDGSGIGAAFISAM 466
++DGSG GAA ++A+
Sbjct: 897 QSEDGSGKGAALVTAV 912
Score = 197 bits (502), Expect = 1e-48, Method: Composition-based stats.
Identities = 156/455 (34%), Positives = 231/455 (50%), Gaps = 46/455 (10%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L+G++S +VRMLP+YV G F L+LG
Sbjct: 37 QFKVTRTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGA 96
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V + V+ + F IP+ + G LF F A + + ++ E
Sbjct: 97 TGASLRVLWVTLTGTKECRVEPRSREFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVE- 155
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNV 208
N+ + LGF FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + +++V
Sbjct: 156 -NQGLKLGFNFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYRIDV 214
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+I+ TG+NACY E A V A T +++
Sbjct: 215 VAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHV----AALDEDRGRTCVSI 270
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F + T FD +D SL G Q EKMI G+YLGE+ R V+VHL+ L
Sbjct: 271 EWGSFYDEDALGPVLTTFDSALDRESLTPGAQRFEKMIGGLYLGELVRLVLVHLTQHGVL 330
Query: 329 ------PAALQTALGNRGSFESRFAGMISADRMPGLQFTRS------TIQKVCGVDVQSI 376
PA L G I D + ++ T + TI + G+ ++
Sbjct: 331 FDGCASPALLSQ-------------GCILLDHVAEMEDTATGTARVHTILQDLGLSPRA- 376
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
D +++ VC V RAAQL A+ A L + Q + +A G VFE+ P F R
Sbjct: 377 SDAELVQCVCVAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGRVFERHPRFLR 436
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
+L++ + +L P CDV + + DG G G A ++A+
Sbjct: 437 ILKETV-MLLAPNCDVSFIPSVDGGGRGVAMVTAV 470
>ref|NP_989543.1| hexokinase 2 [Gallus gallus]
dbj|BAC20933.1| hexokinase2 [Gallus gallus]
Length = 916
Score = 266 bits (681), Expect = 2e-69, Method: Composition-based stats.
Identities = 168/456 (36%), Positives = 256/456 (56%), Gaps = 22/456 (4%)
Query: 23 RAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGR---ESTVRMLPSYVYKADP 79
R + A + +S E + ++ + EM +GL E+TV+MLP+YV
Sbjct: 462 RLAAQHKARQKILEALKLSHEQLLEVKRRMRVEMEKGLGKETHAEATVKMLPTYVCSTPD 521
Query: 80 KRATGVFYALDLGGTNFRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASN 137
G F ALDLGGTNFRVL V + G V+ + IP ++G +LF I
Sbjct: 522 GTEKGDFLALDLGGTNFRVLLVRVRNGMRRGVEMHNKIYSIPLEVMQGTGEELFDHIVHC 581
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
+ +E + + ++PLGFTFSFP +QT ++ G+L++WTKGF G +G DV++LL+
Sbjct: 582 ISDFLEYMGMKGV--SLPLGFTFSFPCKQTNLDEGILLKWTKGFKATGCEGEDVVSLLKE 639
Query: 198 AFG-RVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAV 256
A R ++VVA+ NDTVGT+++ ++DP +VG+I+GTGSNACY E V
Sbjct: 640 AIHRREEFDLDVVAVVNDTVGTMMTCGYEDPYCEVGLIVGTGSNACYMEEMRNVELVEGD 699
Query: 257 AARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIAR 316
R +NME G F T+FDL +D+ SLN G+Q EKMISGMYLGEI R
Sbjct: 700 EGR----MCVNMEWGAFGDNGCLDDIQTEFDLAVDELSLNPGKQRFEKMISGMYLGEIVR 755
Query: 317 RVIVHLSSINCL-PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQS 375
+++ + L + L RG FE++F I +D + LQ RS +Q + G++ +
Sbjct: 756 NILMDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQ-VRSILQHL-GLE-ST 812
Query: 376 IEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKT-QTQG----RATIAIDGSVFEKIPSFR 430
+D I+++VC +V RAAQL + A + K + +G + T+ +DG++++ P F
Sbjct: 813 CDDSIIVKEVCTVVARRAAQLCGAGMAAVVDKIRENRGLDFLKVTVGVDGTLYKLHPHFS 872
Query: 431 RVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
++QD + R L P C+V + ++DGSG GAA I+A+
Sbjct: 873 AIMQDTV-RQLSPCCEVTFLQSEDGSGKGAALITAV 907
Score = 261 bits (667), Expect = 8e-68, Method: Composition-based stats.
Identities = 162/439 (36%), Positives = 247/439 (56%), Gaps = 22/439 (5%)
Query: 40 MSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNF 96
+S ++++++ EM +GL ++V+MLPS+V G F ALDLGGTNF
Sbjct: 31 LSEDTLQEVSERFRKEMEKGLGADTNPTASVKMLPSFVRSTPDGTEDGDFLALDLGGTNF 90
Query: 97 RVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTV 154
RVLRV + + V+ + ++I + + G+ LF IA + ME +D + +
Sbjct: 91 RVLRVKVSDNGLQKVEMESQIYEIHEDLMRGSGMQLFDHIAECLGNFMEKLKIKD--KKL 148
Query: 155 PLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAF-GRVSLKVNVVALCN 213
PLGFTFSFP QTK++ +L+ WTKGF V+G DV++LL+ A R +++VA+ N
Sbjct: 149 PLGFTFSFPCHQTKLDESILVNWTKGFKCSSVEGKDVVSLLRRAIKKRGDFDIDIVAVVN 208
Query: 214 DTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNF 273
DTVGT++S + D +VG+I+GTG+NACY E + D G INME G F
Sbjct: 209 DTVGTMMSCGYDDQNCEVGLIVGTGTNACYMEEMRHI--DLVEGDEGRMC--INMEWGAF 264
Query: 274 DSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL-PAAL 332
T+FD +ID SLN G+Q EKMISGMY+GE+ R ++V ++ L L
Sbjct: 265 GDDGALNDIRTEFDHEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEGLLFQGKL 324
Query: 333 QTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGR 392
+ L G FE+RF I ++ GLQ + K+ G++ S ED +C++V R
Sbjct: 325 SSDLRTTGHFETRFVSAIEKEK-EGLQKAHEILTKL-GLE-PSHEDCLATHRICQIVSTR 381
Query: 393 AAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDV 447
+A L + A L + + R+T+ +DGSV++K P F R L + ++L P+C++
Sbjct: 382 SANLCGATLAARLRRIKEYKGVDPLRSTVGVDGSVYKKYPHFARRLHKTVRKLL-PDCEI 440
Query: 448 RAVLAKDGSGIGAAFISAM 466
R V ++DGSG GAA ++A+
Sbjct: 441 RFVRSEDGSGKGAAMVTAV 459
>emb|CAA43855.1| hexakinase [Kluyveromyces lactis]
Length = 485
Score = 266 bits (680), Expect = 3e-69, Method: Composition-based stats.
Identities = 157/444 (35%), Positives = 248/444 (55%), Gaps = 13/444 (2%)
Query: 33 ALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLG 92
L FT+S E MR I+ + + E+ +GL + + M+P +V + + TG F ALDLG
Sbjct: 29 GLETLFTVSSEKMRSIVKHFISELDKGLSKKGGNIPMIPGWVVEYPTGKETGDFLALDLG 88
Query: 93 GTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNR 152
GTN RV+ V D++ + +++P + G + L+ FIA +K+ ++ P+ ++
Sbjct: 89 GTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIAKCLKEFVDEWYPDGVSE 148
Query: 153 TVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVVALC 212
+PLGFTFS+P Q K+N GVL RWTKGF +GV+G+DV+ +LQ ++++ +NVV L
Sbjct: 149 PLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPMLQEQIEKLNIPINVVRLI 208
Query: 213 NDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARG---SALTPINME 269
NDT GTL++ + DP+ ++G+IIGTG N Y++ S + K + + IN E
Sbjct: 209 NDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEGLLPEDIGPDSPMAINCE 268
Query: 270 SGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHL-SSINCL 328
G+FD+++ VLP TK+D+ ID+ S GQQA EKM SG YLGEI R V++ L S
Sbjct: 269 YGSFDNEH-LVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLGEIMRLVLLDLYDSGFIF 327
Query: 329 PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRL 388
+ L ++ + I D L+ T + ++ +E ++IR + L
Sbjct: 328 KDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNIETTVVER-KLIRKLAEL 386
Query: 389 VRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR----RVLQDNINRILGPE 444
V RAA+L+ A + + A IA DGSVF + P ++ + L+D N +
Sbjct: 387 VGTRAARLTVCGVSA-ICDKRGYKTAHIAADGSVFNRYPGYKEKAAQALKDIYNWDVEKM 445
Query: 445 CD--VRAVLAKDGSGIGAAFISAM 466
D ++ V A+DGSG+GAA I+ +
Sbjct: 446 EDHPIQLVAAEDGSGVGAAIIACL 469
>ref|NP_079406.3| hexokinase domain containing 1 [Homo sapiens]
sp|Q2TB90|HKDC1_HUMAN Putative hexokinase HKDC1 (Hexokinase domain-containing protein 1)
gb|AAI10505.1| Hexokinase domain containing 1 [Homo sapiens]
gb|AAI10506.2| Hexokinase domain containing 1 [Homo sapiens]
gb|EAW54318.1| hexokinase domain containing 1, isoform CRA_b [Homo sapiens]
Length = 917
Score = 265 bits (678), Expect = 4e-69, Method: Composition-based stats.
Identities = 168/453 (37%), Positives = 253/453 (55%), Gaps = 23/453 (5%)
Query: 23 RAVKRDVAMAALTNQFTMSVES-MRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKR 81
+ + R +A+ LT + + V++ MR + Y L + GL +TVRMLP+YV
Sbjct: 468 KQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGL----ATVRMLPTYVCGLPDGT 523
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA-VVDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F ALDLGGTNFRVL V + G V F IP ++G +LF I +
Sbjct: 524 EKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIAD 583
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
++ + ++PLGFTFSFP Q +++G LI WTKGF +G DV+ +L+ A
Sbjct: 584 FLDYMGLK--GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIK 641
Query: 201 RVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R + +++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E ++ +
Sbjct: 642 RRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMED----MRNIEMVEG 697
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
G IN E G F T++D ++D+ SLN G+Q EKM SGMYLGEI R+++
Sbjct: 698 GEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQIL 757
Query: 320 VHLSSINCL-PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ L+ L + L RG FE++F I +DR+ LQ R I + G+D + ED
Sbjct: 758 IDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRR--ILQQLGLD-STCED 814
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPLVK-TQTQG----RATIAIDGSVFEKIPSFRRVL 433
++++VC V RAAQL + A + K + QG R T+ +DG++++ P F R+L
Sbjct: 815 SIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRIL 874
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
Q+ + L P CDV +L++DGSG GAA I+A+
Sbjct: 875 QETVKE-LAPRCDVTFMLSEDGSGKGAALITAV 906
Score = 223 bits (567), Expect = 3e-56, Method: Composition-based stats.
Identities = 158/440 (35%), Positives = 240/440 (54%), Gaps = 24/440 (5%)
Query: 40 MSVESMRQIMTYLLYEMVEGLE---GRESTVRMLPSYVYKADPKRATGVFYALDLGGTNF 96
+S +++ IM EM +GL + V+MLP++V G F +LDLGG+ F
Sbjct: 31 LSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFLSLDLGGSKF 90
Query: 97 RVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDL-NRT 153
RVL+V E V + + P + GN T+LF ++A + M+T+ DL ++
Sbjct: 91 RVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTK---DLKHKK 147
Query: 154 VPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALC 212
+PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A R + V+++AL
Sbjct: 148 LPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDVDILALV 207
Query: 213 NDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGN 272
NDTVGT+++ + DP +VGVIIGTG+NACY E S + D G IN E G
Sbjct: 208 NDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNI--DLVEGDEGRMC--INTEWGA 263
Query: 273 FDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAAL 332
F T+FD ++D SLN G+Q EKMISG+YLGE+ R +++ ++ L
Sbjct: 264 FGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGE 323
Query: 333 Q-TALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRG 391
+ +AL +G E+R + + GL TR + + G++ S D ++ VC +V
Sbjct: 324 KSSALHTKGKIETRHVAAMEKYK-EGLANTREILVDL-GLE-PSEADCIAVQHVCTIVSF 380
Query: 392 RAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECD 446
R+A L A+ A L K + R T+ +DG++++ P + + L + R L P CD
Sbjct: 381 RSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLH-KVVRKLVPSCD 439
Query: 447 VRAVLAKDGSGIGAAFISAM 466
VR +L++ GS GAA ++A+
Sbjct: 440 VRFLLSESGSTKGAAMVTAV 459
>dbj|BAF83713.1| unnamed protein product [Homo sapiens]
Length = 917
Score = 265 bits (678), Expect = 4e-69, Method: Composition-based stats.
Identities = 168/453 (37%), Positives = 253/453 (55%), Gaps = 23/453 (5%)
Query: 23 RAVKRDVAMAALTNQFTMSVES-MRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKR 81
+ + R +A+ LT + + V++ MR + Y L + GL +TVRMLP+YV
Sbjct: 468 KQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGL----ATVRMLPTYVCGLPDGT 523
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA-VVDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F ALDLGGTNFRVL V + G V F IP ++G +LF I +
Sbjct: 524 EKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIAD 583
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
++ + ++PLGFTFSFP Q +++G LI WTKGF +G DV+ +L+ A
Sbjct: 584 FLDYMGLK--GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIK 641
Query: 201 RVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R + +++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E ++ +
Sbjct: 642 RRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMED----MRNIEMVEG 697
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
G IN E G F T++D ++D+ SLN G+Q EKM SGMYLGEI R+++
Sbjct: 698 GEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQIL 757
Query: 320 VHLSSINCL-PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ L+ L + L RG FE++F I +DR+ LQ R I + G+D + ED
Sbjct: 758 IDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRR--ILQQLGLD-STCED 814
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPLVK-TQTQG----RATIAIDGSVFEKIPSFRRVL 433
++++VC V RAAQL + A + K + QG R T+ +DG++++ P F R+L
Sbjct: 815 SIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRIL 874
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
Q+ + L P CDV +L++DGSG GAA I+A+
Sbjct: 875 QETVKE-LAPRCDVTFMLSEDGSGKGAALITAV 906
Score = 222 bits (566), Expect = 5e-56, Method: Composition-based stats.
Identities = 158/440 (35%), Positives = 240/440 (54%), Gaps = 24/440 (5%)
Query: 40 MSVESMRQIMTYLLYEMVEGLE---GRESTVRMLPSYVYKADPKRATGVFYALDLGGTNF 96
+S +++ IM EM +GL + V+MLP++V G F +LDLGG+ F
Sbjct: 31 LSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFLSLDLGGSKF 90
Query: 97 RVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDL-NRT 153
RVL+V E V + + P + GN T+LF ++A + M+T+ DL ++
Sbjct: 91 RVLKVQVAEEGKRHVQMESQFYPTPNDIIRGNGTELFEYVADCLADFMKTK---DLKHKK 147
Query: 154 VPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALC 212
+PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A R + V+++AL
Sbjct: 148 LPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDVDILALV 207
Query: 213 NDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGN 272
NDTVGT+++ + DP +VGVIIGTG+NACY E S + D G IN E G
Sbjct: 208 NDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNI--DLVEGDEGRMC--INTEWGA 263
Query: 273 FDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAAL 332
F T+FD ++D SLN G+Q EKMISG+YLGE+ R +++ ++ L
Sbjct: 264 FGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGE 323
Query: 333 Q-TALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRG 391
+ +AL +G E+R + + GL TR + + G++ S D ++ VC +V
Sbjct: 324 KSSALHTKGKIETRHVAAMEKYK-EGLANTREILVDL-GLE-PSEADCIAVQHVCTIVSF 380
Query: 392 RAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECD 446
R+A L A+ A L K + R T+ +DG++++ P + + L + R L P CD
Sbjct: 381 RSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLH-KVVRKLVPSCD 439
Query: 447 VRAVLAKDGSGIGAAFISAM 466
VR +L++ GS GAA ++A+
Sbjct: 440 VRFLLSESGSTKGAAMVTAV 459
>ref|NP_998231.1| hexokinase 2 [Danio rerio]
gb|AAH45496.1| Hexokinase 2 [Danio rerio]
Length = 919
Score = 265 bits (677), Expect = 6e-69, Method: Composition-based stats.
Identities = 164/456 (35%), Positives = 254/456 (55%), Gaps = 21/456 (4%)
Query: 23 RAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGR---ESTVRMLPSYVYKADP 79
R K+ + + + + + ++ + EM GL + +TV+MLP++V
Sbjct: 464 RLAKQHAERQRVLDTLRLGRDQLLEVKKRMEEEMKRGLAKKTHNNATVKMLPTFVRSTPD 523
Query: 80 KRATGVFYALDLGGTNFRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASN 137
G F ALDLGGTNFRVL V + G V+ + + IP+ +G +LF I
Sbjct: 524 GTERGDFLALDLGGTNFRVLLVRVRGGKRRNVEMNNKIYTIPQDITQGTGEELFDHIVHC 583
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
+ +E + ++PLGFTFSFP Q K+++G+LI+WTKGF G +G DV +LL+
Sbjct: 584 IADFLEYMGMK--GASLPLGFTFSFPCHQDKLDQGILIKWTKGFKASGCEGEDVASLLKD 641
Query: 198 AFGRV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAV 256
A R ++VVA+ NDTVGT+++ ++DP+ +VG+I+GTG+NACY E S V
Sbjct: 642 AIHRCEEFDLDVVAVVNDTVGTMMTCGYEDPQCEVGLIVGTGTNACYMEEMSNVELVDGD 701
Query: 257 AARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIAR 316
R +NME G F + T+FD +DD S G+Q EKMISGMYLGEI R
Sbjct: 702 EGR----MCVNMEWGAFGDQGELDDIWTEFDRAVDDQSTYPGRQRYEKMISGMYLGEIVR 757
Query: 317 RVIVHLSSINCL-PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQS 375
V++H ++ L L L RG FE++F I +DR+ L+ RS +Q + G+ +
Sbjct: 758 NVLLHFTAKGLLFRGKLSERLKTRGIFETKFLSQIESDRL-ALRQVRSILQHL-GLTSST 815
Query: 376 IEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFR 430
+D ++++VC +V RAAQL + A + K + Q T+ +DG++++ P F
Sbjct: 816 CDDSILVKEVCSVVSKRAAQLCGAGLAAVVDKIRLNRGLNQLSITVGVDGTLYKLHPHFA 875
Query: 431 RVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
++++ + R L P C+V V ++DGSG GAA I+A+
Sbjct: 876 TIMRETL-RDLAPNCEVSLVQSEDGSGKGAALITAV 910
Score = 241 bits (616), Expect = 6e-62, Method: Composition-based stats.
Identities = 158/440 (35%), Positives = 238/440 (54%), Gaps = 22/440 (5%)
Query: 40 MSVESMRQIMTYLLYEMVEGLEGREST----VRMLPSYVYKADPKRATGVFYALDLGGTN 95
+S E++ + EM +GL GR++ V+MLP++V TG F ALDLGGTN
Sbjct: 31 LSNENLMDVSKRFRKEMDKGL-GRDTNPTAAVKMLPTFVRSTPDGTETGDFLALDLGGTN 89
Query: 96 FRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRT 153
FRVL V + V+ + I + + G ++LF IA + +E ++ +
Sbjct: 90 FRVLLVKVSSNGMQKVEMENQIYAISENIMRGCGSELFDHIAECLANFLEKLGIKE--KK 147
Query: 154 VPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAF-GRVSLKVNVVALC 212
+PLGFTFSFP +QTK++ L+ WTKGF GV+G DV++LL+ A R +++VA+
Sbjct: 148 LPLGFTFSFPCQQTKLDESFLVSWTKGFKASGVEGKDVVSLLRKAIRKRGDFDIDIVAVI 207
Query: 213 NDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGN 272
NDTVGT+++ + D ++G+I+GTG+NACY E + R +NME G
Sbjct: 208 NDTVGTMMTCGYDDHHCEIGLIVGTGTNACYMEEMRHLELVDGDEGR----MCVNMEWGA 263
Query: 273 FDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAAL 332
F T+FD +ID SLN G+Q EKMISGMY+GE+ R ++V ++ L
Sbjct: 264 FGDDGALDDLRTEFDREIDAGSLNPGKQLFEKMISGMYMGELVRLILVKMAKDGLLFQGH 323
Query: 333 QTA-LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRG 391
T L G F++ F I + + + + G+D + ED + VC++V
Sbjct: 324 TTPDLLTTGHFQTSFVSAIENRKDDEGIVSAEQVLRGLGLD-PTPEDCVATQRVCQIVST 382
Query: 392 RAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECD 446
RAA L A+ A L K + R +I +DGSV++ P F R L + R L P+CD
Sbjct: 383 RAAHLCAASLAAVLRQIRDNKASDRLRTSIGVDGSVYKNHPEFARRLNKMV-RSLVPDCD 441
Query: 447 VRAVLAKDGSGIGAAFISAM 466
VR + ++DGSG GAA ++A+
Sbjct: 442 VRFLRSEDGSGKGAAMVTAV 461
>emb|CAH71500.1| hexokinase domain containing 1 [Homo sapiens]
Length = 917
Score = 265 bits (677), Expect = 6e-69, Method: Composition-based stats.
Identities = 168/453 (37%), Positives = 253/453 (55%), Gaps = 23/453 (5%)
Query: 23 RAVKRDVAMAALTNQFTMSVES-MRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKR 81
+ + R +A+ LT + + V++ MR + Y L + GL +TVRMLP+YV
Sbjct: 468 KQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGL----ATVRMLPTYVCGLPDGT 523
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA-VVDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F ALDLGGTNFRVL V + G V F IP ++G +LF I +
Sbjct: 524 EKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIAD 583
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
++ + ++PLGFTFSFP Q +++G LI WTKGF +G DV+ +L+ A
Sbjct: 584 FLDYMGLK--GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIK 641
Query: 201 RVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R + +++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E ++ +
Sbjct: 642 RRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMED----MRNIEMVEG 697
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
G IN E G F T++D ++D+ SLN G+Q EKM SGMYLGEI R+++
Sbjct: 698 GEGKMCINTEWGGFGDNGCIDDIWTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQIL 757
Query: 320 VHLSSINCL-PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ L+ L + L RG FE++F I +DR+ LQ R I + G+D + ED
Sbjct: 758 IDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRR--ILQQLGLD-STCED 814
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPLVK-TQTQG----RATIAIDGSVFEKIPSFRRVL 433
++++VC V RAAQL + A + K + QG R T+ +DG++++ P F R+L
Sbjct: 815 SIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRIL 874
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
Q+ + L P CDV +L++DGSG GAA I+A+
Sbjct: 875 QETVKE-LAPRCDVTFMLSEDGSGKGAALITAV 906
Score = 223 bits (567), Expect = 4e-56, Method: Composition-based stats.
Identities = 158/440 (35%), Positives = 240/440 (54%), Gaps = 24/440 (5%)
Query: 40 MSVESMRQIMTYLLYEMVEGLE---GRESTVRMLPSYVYKADPKRATGVFYALDLGGTNF 96
+S +++ IM EM +GL + V+MLP++V G F +LDLGG+ F
Sbjct: 31 LSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFLSLDLGGSKF 90
Query: 97 RVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDL-NRT 153
RVL+V E V + + P + GN T+LF ++A + M+T+ DL ++
Sbjct: 91 RVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTK---DLKHKK 147
Query: 154 VPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALC 212
+PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A R + V+++AL
Sbjct: 148 LPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDVDILALV 207
Query: 213 NDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGN 272
NDTVGT+++ + DP +VGVIIGTG+NACY E S + D G IN E G
Sbjct: 208 NDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNI--DLVEGDEGRMC--INTEWGA 263
Query: 273 FDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAAL 332
F T+FD ++D SLN G+Q EKMISG+YLGE+ R +++ ++ L
Sbjct: 264 FGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGE 323
Query: 333 Q-TALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRG 391
+ +AL +G E+R + + GL TR + + G++ S D ++ VC +V
Sbjct: 324 KSSALHTKGKIETRHVAAMEKYK-EGLANTREILVDL-GLE-PSEADCIAVQHVCTIVSF 380
Query: 392 RAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECD 446
R+A L A+ A L K + R T+ +DG++++ P + + L + R L P CD
Sbjct: 381 RSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLH-KVVRKLVPSCD 439
Query: 447 VRAVLAKDGSGIGAAFISAM 466
VR +L++ GS GAA ++A+
Sbjct: 440 VRFLLSESGSTKGAAMVTAV 459
>gb|AAH12337.1| HKDC1 protein [Homo sapiens]
Length = 677
Score = 265 bits (676), Expect = 9e-69, Method: Composition-based stats.
Identities = 168/453 (37%), Positives = 253/453 (55%), Gaps = 23/453 (5%)
Query: 23 RAVKRDVAMAALTNQFTMSVES-MRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKR 81
+ + R +A+ LT + + V++ MR + Y L + GL +TVRMLP+YV
Sbjct: 228 KQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGL----ATVRMLPTYVCGLPDGT 283
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA-VVDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F ALDLGGTNFRVL V + G V F IP ++G +LF I +
Sbjct: 284 EKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIAD 343
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
++ + ++PLGFTFSFP Q +++G LI WTKGF +G DV+ +L+ A
Sbjct: 344 FLDYMGLK--GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIK 401
Query: 201 RVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R + +++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E ++ +
Sbjct: 402 RRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMED----MRNIEMVEG 457
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
G IN E G F T++D ++D+ SLN G+Q EKM SGMYLGEI R+++
Sbjct: 458 GEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQIL 517
Query: 320 VHLSSINCL-PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ L+ L + L RG FE++F I +DR+ LQ R I + G+D + ED
Sbjct: 518 IDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRR--ILQQLGLD-STCED 574
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPLVK-TQTQG----RATIAIDGSVFEKIPSFRRVL 433
++++VC V RAAQL + A + K + QG R T+ +DG++++ P F R+L
Sbjct: 575 SIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRIL 634
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
Q+ + L P CDV +L++DGSG GAA I+A+
Sbjct: 635 QETVKE-LAPRCDVTFMLSEDGSGKGAALITAV 666
Score = 82.0 bits (201), Expect = 1e-13, Method: Composition-based stats.
Identities = 68/207 (32%), Positives = 110/207 (53%), Gaps = 10/207 (4%)
Query: 266 INMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSI 325
IN E G F T+FD ++D SLN G+Q EKMISG+YLGE+ R +++ ++
Sbjct: 17 INTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKA 76
Query: 326 NCLPAALQ-TALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRD 384
L + +AL +G E+R + + GL TR + + G++ S D ++
Sbjct: 77 GLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREILVDL-GLE-PSEADCIAVQH 133
Query: 385 VCRLVRGRAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNINR 439
VC +V R+A L A+ A L K + R T+ +DG++++ P + + L + R
Sbjct: 134 VCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLH-KVVR 192
Query: 440 ILGPECDVRAVLAKDGSGIGAAFISAM 466
L P CDVR +L++ GS GAA ++A+
Sbjct: 193 KLVPSCDVRFLLSESGSTKGAAMVTAV 219
>ref|XP_421579.2| PREDICTED: similar to Hexokinase domain containing 1 [Gallus
gallus]
Length = 917
Score = 263 bits (672), Expect = 2e-68, Method: Composition-based stats.
Identities = 164/448 (36%), Positives = 250/448 (55%), Gaps = 26/448 (5%)
Query: 33 ALTNQFTMSVESMRQIMTYLLYEMVEGLEGRES----TVRMLPSYVYKADPKRATGVFYA 88
A+ F +++E++R + + E+ GL+ RE+ TV+MLP+YV G + A
Sbjct: 472 AVLAPFVLTLETLRDVKNKMRTELEYGLK-RETQDRATVKMLPTYVCGTPDGTEKGKYLA 530
Query: 89 LDLGGTNFRVLRVACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRA 146
LDLGGTNFRVL V + G V F IP ++G +LF I + +E
Sbjct: 531 LDLGGTNFRVLLVKIRSGRRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLEYMG 590
Query: 147 PEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LK 205
+ +PLGFTFSFP Q +++G L+ WTKGF +G DV+ +L+ A R +
Sbjct: 591 IK--GARLPLGFTFSFPCRQASIDKGTLVGWTKGFKATDCEGEDVVDMLREAIRRRNEFD 648
Query: 206 VNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTP 265
+++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E K+ +
Sbjct: 649 LDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNVCYMED----MKNIEIVDGNEGKMC 704
Query: 266 INMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSI 325
IN E G F TK+D ++D+ SLN G+Q EKM SGMYLGEI R++++ L+
Sbjct: 705 INTEWGGFGDNGCIDNIRTKYDKEVDEGSLNAGKQRYEKMTSGMYLGEIVRQILIDLTKQ 764
Query: 326 NCL-PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRD 384
L + +L RG FE++F I +DR+ LQ R I + G+D + +D I+++
Sbjct: 765 GLLFRGQISESLRKRGIFETKFLSQIESDRLALLQVRR--ILQQLGLD-STCDDSIIVKE 821
Query: 385 VCRLVRGRAAQLSASFCCAPLVKTQTQGRA------TIAIDGSVFEKIPSFRRVLQDNIN 438
VC V RAAQL + A +V+ + + R T+ +DG++++ P F RVLQ+ +
Sbjct: 822 VCGAVSRRAAQLCGA-GLAAIVEKKRENRGAEHLQITVGVDGTLYKLHPHFSRVLQETVK 880
Query: 439 RILGPECDVRAVLAKDGSGIGAAFISAM 466
L P CDV +L++DGSG GAA I+A+
Sbjct: 881 E-LAPRCDVTFMLSEDGSGKGAALITAV 907
Score = 222 bits (565), Expect = 5e-56, Method: Composition-based stats.
Identities = 151/442 (34%), Positives = 243/442 (54%), Gaps = 28/442 (6%)
Query: 40 MSVESMRQIMTYLLYEMVEGLEGRES----TVRMLPSYVYKADPKRATGVFYALDLGGTN 95
+S + + +M EMV+GL GR++ TV+MLPS+V G F A+DLGG+
Sbjct: 31 LSDDVLLDVMARFQAEMVKGL-GRDTNPTATVKMLPSFVRSLPDGSEKGDFLAVDLGGSQ 89
Query: 96 FRVLRVAC----KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLN 151
FR L+V K+ + ++S + PK ++G+ +LF ++A + ME+R + +
Sbjct: 90 FRALKVKVFNDGKQSSQLESEF--YPTPKEVIQGSGAELFSYVADCLSDFMESRNLK--H 145
Query: 152 RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVA 210
+PLGFTFSFP +QTK+ G+L+ WTK F +GVQG DV++ L+ A + + V+V+A
Sbjct: 146 EKLPLGFTFSFPCKQTKLEEGILLSWTKHFKARGVQGTDVVSSLRNALQKHKDIDVDVLA 205
Query: 211 LCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMES 270
+ NDTVGT+++ + DP ++G+IIGTG+NACY E + R IN E
Sbjct: 206 MVNDTVGTMMTCGYDDPRCEIGLIIGTGTNACYMEEMRHINLVEGDEGR----MCINTEW 261
Query: 271 GNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL-P 329
G F T+FD ++D SLN G+Q EKMIS +YLGE+ R +++ ++ L
Sbjct: 262 GAFGDDGALDDLRTEFDRELDLGSLNPGKQLFEKMISSLYLGELVRLILLKMTKEGLLFN 321
Query: 330 AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLV 389
+ AL +G E + + + GL T+ + ++ S +D ++ VC +V
Sbjct: 322 GKVSAALLTKGKIEMKHVSAMEKYK-EGLSNTKEILTELN--LFPSEDDCIAVQHVCTIV 378
Query: 390 RGRAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPE 444
R+A L A+ A L K + R T+ IDG +++ P + + L + R++ P
Sbjct: 379 SFRSANLCAAALAAILTRLRENKKLLRLRTTVGIDGGLYKTHPQYPKRLHKVVRRLV-PN 437
Query: 445 CDVRAVLAKDGSGIGAAFISAM 466
CDVR +L++ GS GAA ++A+
Sbjct: 438 CDVRFLLSQSGSAKGAAMVTAV 459
>ref|XP_001086179.1| PREDICTED: hexokinase 3 [Macaca mulatta]
Length = 923
Score = 263 bits (671), Expect = 3e-68, Method: Composition-based stats.
Identities = 160/437 (36%), Positives = 256/437 (58%), Gaps = 21/437 (4%)
Query: 38 FTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFR 97
F ++ + + + + MV+GL G S++RMLP++V G F ALDLGGTNFR
Sbjct: 490 FRLNHDQLAAVQAQMRKAMVKGLRGEASSLRMLPTFVRATPDGSERGDFLALDLGGTNFR 549
Query: 98 VLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLN-RTVPL 156
VL V + V ++ + IP+ +G+ LF I + M+ + + L+ +++PL
Sbjct: 550 VLLV--RVTTSVQITSQIYSIPESVAQGSGQQLFDHIVDCI---MDFQQKQGLSGQSLPL 604
Query: 157 GFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALCNDT 215
GFTFSFP Q +++G+L+ WTKGF+ +G DV+ LL+ A R ++++NVVA+ NDT
Sbjct: 605 GFTFSFPCRQLGLDQGILLNWTKGFNASDCEGQDVVNLLREAIARRQAVELNVVAIVNDT 664
Query: 216 VGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDS 275
VGT++S ++DP ++G+I+GTG+NACY E V P + R INME G F
Sbjct: 665 VGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNVAGVPGDSGR----MCINMEWGAFGD 720
Query: 276 KYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAALQTA 335
+ +T FD +D AS+N G+Q LEKMISGMYLGEI R V++HL+S+ L QT
Sbjct: 721 DGSLAMLSTCFDASVDQASINPGKQRLEKMISGMYLGEIVRHVLLHLTSLGVLFRGQQTQ 780
Query: 336 -LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAA 394
L R F+++F I +D + L+ R+ ++ + G+ + S +D ++ +VC+ V RAA
Sbjct: 781 RLQTRDIFKTKFLSEIESDSL-ALRQVRAILEDL-GLPLTS-DDALMVLEVCQAVSQRAA 837
Query: 395 QLSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRA 449
QL + A + K + + ++ +DG++++ P F ++ + R L P C V
Sbjct: 838 QLCGAGVAAVVEKIRENRGLEELAVSVGVDGTLYKLHPHFSSLVAATV-RELAPRCVVTF 896
Query: 450 VLAKDGSGIGAAFISAM 466
+ ++DGSG GAA ++A+
Sbjct: 897 LQSEDGSGKGAALVTAV 913
Score = 197 bits (501), Expect = 1e-48, Method: Composition-based stats.
Identities = 155/444 (34%), Positives = 224/444 (50%), Gaps = 24/444 (5%)
Query: 37 QFTMSVESMRQIMTYLLYEMVEGLEGRES---TVRMLPSYVYKADPKRATGVFYALDLG- 92
QF ++ ++QI LL M + L G+ S VRMLP+YV G F L+LG
Sbjct: 39 QFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTEQGDFMVLELGA 98
Query: 93 -GTNFRVLRVACK--EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
G + RVL V EG V+ + F IP+ + G LF F A + + ++ +
Sbjct: 99 TGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCLSEFLDAQPVS- 157
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNV 208
+ + LGF+FSFP QT ++R LI WTKGF GV+G DV+ LL+ A R + ++V
Sbjct: 158 -KQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIQRHGAYNIDV 216
Query: 209 VALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINM 268
VA+ NDTVGT++ +VG+++ TG+NACY E A V AV +++
Sbjct: 217 VAVVNDTVGTMMGCELGARPCEVGLVVDTGTNACYMEEARHV----AVLDEDRGRVCVSV 272
Query: 269 ESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL 328
E G+F T FD +D SLN G Q EKMI G+YLGE+ R V+ HL+ L
Sbjct: 273 EWGSFSDVGALGPVLTTFDHTLDHESLNPGAQRFEKMIGGLYLGELVRLVLAHLAQRGVL 332
Query: 329 -PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCR 387
AL +RGS + D G R+ +Q + G+ D+ +++ VC
Sbjct: 333 FGGGTSPALLSRGSILLEHVAEME-DPSAGAARVRAILQDL-GLS-PGASDVELVQHVCA 389
Query: 388 LVRGRAAQLSASFCCAPL-----VKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILG 442
V RAAQL A+ A L + Q + +A G V E+ P F +LQ + +L
Sbjct: 390 AVCTRAAQLCAAALAAVLSHLQHSREQQTLQVAVATGGRVCERHPRFCGILQGTV-MLLA 448
Query: 443 PECDVRAVLAKDGSGIGAAFISAM 466
PECDV + + DG G G A ++A+
Sbjct: 449 PECDVSFIPSADGGGRGVAMVTAV 472
>ref|XP_717405.1| hexokinase II [Candida albicans SC5314]
gb|EAK98436.1| likely hexokinase II [Candida albicans SC5314]
Length = 484
Score = 261 bits (668), Expect = 7e-68, Method: Composition-based stats.
Identities = 156/452 (34%), Positives = 244/452 (53%), Gaps = 24/452 (5%)
Query: 30 AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYAL 89
A+ + QFT+S + +R I+ + + E+ GL + M+P +V + TG + A+
Sbjct: 26 ALKPIQEQFTISADKLRAIVKHFISELDRGLSKAGGNIPMIPGWVMDFPTGKETGSYLAI 85
Query: 90 DLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
DLGGTN RV+ V D++ S F +P + + +L+ FIA +K+ ++ P+
Sbjct: 86 DLGGTNLRVVLVKLGGNRDFDTTQSKFALPAHMRTATSDELWDFIAKCLKEFVDEIYPDG 145
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVV 209
+ +PLGFTFS+P Q ++N G+L RWTKG+S G++G DV+ +LQ A +V + ++VV
Sbjct: 146 CSEPLPLGFTFSYPASQNRINEGILQRWTKGWSIDGIEGKDVVPMLQKAIKKVGVPIDVV 205
Query: 210 ALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD-PAVAARGSALTP--- 265
AL NDT GTL++ + DPE ++G+I GTG N YF+ V KD P + + + P
Sbjct: 206 ALINDTTGTLVASMYTDPEAKMGLIFGTGVNGAYFD----VVKDIPKLEGKCPSDIPPES 261
Query: 266 ---INMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHL 322
IN E G+FD++ +++LP TK+D+ ID+ S GQQ EKMISG YLGE+ R +++
Sbjct: 262 PMAINCEYGSFDNE-KYILPRTKYDVQIDEESPRPGQQTFEKMISGYYLGEVLRLILLEF 320
Query: 323 SSINCLPAALQT--ALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLR 380
+ L Q L ++ + I D L ++ G++ E +
Sbjct: 321 AEEKKLIFKGQNLDKLKVPYVMDASYPSKIEEDPFENLSDVADLFREKLGIETTEPER-K 379
Query: 381 IIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRAT--IAIDGSVFEKIPSFRRVLQDNIN 438
IIR + L+ R+A+ S C Q +G T A DGSV+ K P F+ +
Sbjct: 380 IIRCLAELIGERSARFSV---CGIAAICQKRGYKTAHCAADGSVYNKYPGFKERTAQALR 436
Query: 439 RILGPECDVR----AVLAKDGSGIGAAFISAM 466
I DV+ V A+DGSG+GAA I+A+
Sbjct: 437 DIYEWPADVKDPIIIVPAEDGSGVGAAVIAAL 468
>ref|XP_001364147.1| PREDICTED: similar to Hexokinase domain containing 1 [Monodelphis
domestica]
Length = 917
Score = 261 bits (668), Expect = 7e-68, Method: Composition-based stats.
Identities = 162/454 (35%), Positives = 259/454 (57%), Gaps = 24/454 (5%)
Query: 23 RAVKRDVAMAALTNQFTMSVES-MRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKR 81
+ + +A+ LT + +SV++ MR M Y L + + L +TV+MLP+YV
Sbjct: 468 KVIDEVLALFQLTREHLVSVKNKMRSEMEYGLKKETQPL----ATVKMLPTYVCAMPDGT 523
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA-VVDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G + ALDLGGTNFRVL V + G V F IP ++G +LF I +
Sbjct: 524 EKGKYLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIAD 583
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
++ + ++ +PLGFTFSFP +Q +++G+L+ WTKGF +G DV+ +L+ A
Sbjct: 584 FLDYMGIKGASK-LPLGFTFSFPCKQNCLDKGILVEWTKGFKATDCEGEDVVDMLREAIK 642
Query: 201 RVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R + +++VVA+ NDTVGT+++ ++DP ++G+I GTGSN CY E ++ +
Sbjct: 643 RRNEFELDVVAVLNDTVGTMMTCAYEDPACEIGLIAGTGSNVCYMEE----MRNIELVEG 698
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
+ IN E G F T++D+++D+ SLN G+Q EKM SGMYLGEI R+++
Sbjct: 699 DEGIMCINTEWGGFGDNGCLDEIRTQYDVEVDEGSLNPGKQRYEKMTSGMYLGEIVRQIL 758
Query: 320 VHLSSINCL-PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ L+ L + L RG FE++F I +DR+ LQ R I + G+D + ED
Sbjct: 759 IDLTKHGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRR--ILQQLGLD-STCED 815
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRA------TIAIDGSVFEKIPSFRRV 432
++++VC V RAAQL + A +V+ + + R T+ +DG++++ P F R+
Sbjct: 816 SIVVKEVCGAVSRRAAQLCGA-GLAAIVEKRREDRGLERLAITVGVDGTLYKLHPHFSRI 874
Query: 433 LQDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
L++ ++ L P CDV +L++DGSG GAA I+A+
Sbjct: 875 LRETVH-ALAPRCDVTFMLSEDGSGKGAALITAV 907
Score = 231 bits (590), Expect = 7e-59, Method: Composition-based stats.
Identities = 157/441 (35%), Positives = 248/441 (56%), Gaps = 26/441 (5%)
Query: 40 MSVESMRQIMTYLLYEMVEGLEGREST----VRMLPSYVYKADPKRATGVFYALDLGGTN 95
+S +++ IMT EM +GL G+++ V+MLP++V G F ALDLGG+
Sbjct: 31 LSDDTLLDIMTRFRAEMEKGL-GKDTNPTACVKMLPTFVRAIPDGSEKGEFLALDLGGSK 89
Query: 96 FRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDL-NR 152
FRVL V E V + + PK + G+ ++LF ++A ++TR DL ++
Sbjct: 90 FRVLTVRVSEEGKPNVHMESQIYPTPKEIIHGSGSELFDYVADCAADFVKTR---DLAHK 146
Query: 153 TVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVAL 211
+PLG TFSFP +Q+K+ G+L+ WTK F +GVQ DV++ L A R + V+V+AL
Sbjct: 147 KLPLGLTFSFPCQQSKLEEGILLSWTKKFKVRGVQDTDVVSSLTRALRRHQDVDVDVLAL 206
Query: 212 CNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESG 271
NDTV T+++ + DP +VGVIIGTG+NACY E S + R IN E G
Sbjct: 207 VNDTVATMMTCAYDDPRCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR----MAINTEWG 262
Query: 272 NFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL-PA 330
F T+FD ++D S+N G+Q EKMISG+Y+GE+ R +++ ++ L
Sbjct: 263 AFGEDGALEDIRTEFDRELDLGSINPGKQLFEKMISGLYIGELVRLILLKMTKAGLLFQG 322
Query: 331 ALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVR 390
+AL +G E+R ++ + GLQ TR ++++ G++ S ED ++ VC +V
Sbjct: 323 EKSSALHTKGKIETRHVALMEKYK-EGLQNTREILREL-GLE-PSEEDCVAVQHVCTIVS 379
Query: 391 GRAAQLSASFCCAPLVKTQ-----TQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPEC 445
R+A L A+ A L + + T+ R T+ +DG++++ P + + L + R L P C
Sbjct: 380 FRSANLCAAALAAILNRLRENRRLTRLRTTVGMDGTLYKTHPQYPKRLH-KVVRKLVPNC 438
Query: 446 DVRAVLAKDGSGIGAAFISAM 466
DVR +L++ GS GAA ++A+
Sbjct: 439 DVRFLLSESGSAKGAAMVTAV 459
>ref|XP_001760948.1| hexokinase protein HXK4 [Physcomitrella patens subsp. patens]
gb|EDQ74337.1| hexokinase protein HXK4 [Physcomitrella patens subsp. patens]
Length = 489
Score = 261 bits (667), Expect = 8e-68, Method: Composition-based stats.
Identities = 171/445 (38%), Positives = 241/445 (54%), Gaps = 36/445 (8%)
Query: 45 MRQIMTYLLYEMVEGLEGR-ESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVAC 103
+R I + EM EGL+ E ++MLP+Y+ G+FYA+DLGGTNFRVLRV
Sbjct: 30 LRHIAQAMATEMQEGLDHPGERKLKMLPTYLECLPTGNERGLFYAIDLGGTNFRVLRVQL 89
Query: 104 --KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED-----LNRTVPL 156
KEG ++ + IP+ + G++ DLFGF+A + + + A LN+ +
Sbjct: 90 DGKEGRILKQESIQVPIPQEVMTGSSKDLFGFLAKTIVQFVSREADLGFECVALNQKRDI 149
Query: 157 GFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNVVALCNDT 215
GFTFSFPV QTKVN G + WTKGFS G DV+ L+ A + S+ VV L NDT
Sbjct: 150 GFTFSFPVNQTKVNGGSINAWTKGFSISDGVGEDVVDQLEIALADMGSVNTKVVCLVNDT 209
Query: 216 VGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVT--KDPAVAARGSALTPINMESGNF 273
VGTL + + + VGVI+GTGSNACY E A+A++ P A LT +N+E GNF
Sbjct: 210 VGTLAQCRYWNDDAMVGVILGTGSNACYVERAAAISCWSSPPEA---DDLTVVNIEWGNF 266
Query: 274 DSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCL-PAAL 332
S+ +LP T D +D SLN GQQ EKMI GMYLGEI RRV++ ++ L + +
Sbjct: 267 CSE---LLPRTFADEGLDADSLNPGQQEFEKMIGGMYLGEILRRVLLKMAEDTGLFGSEI 323
Query: 333 QTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGR 392
L S + + D L+ S I++ GV ++ +++ DVC ++ R
Sbjct: 324 PERLTKPFSLLTPHMSTMHGDDTSSLEVVGSVIEEAIGVKYTTLATRKVVYDVCDIIAER 383
Query: 393 AAQLSASFCCAPLVKTQTQG----------------RATIAIDGSVFEKIPSFRRVLQDN 436
A+LSA+ L K G + IAIDGS++EK P FR ++D
Sbjct: 384 GARLSAAGIVGILTKINRCGDLMLSCLTTPNDTEVKKTVIAIDGSLYEKYPKFRNYMEDA 443
Query: 437 INRILGPEC--DVRAVLAKDGSGIG 459
+ +LG + +V L+KDGSG+G
Sbjct: 444 MKEMLGEDYANNVTTTLSKDGSGVG 468
>ref|XP_001110556.1| PREDICTED: similar to hexokinase domain containing 1 [Macaca
mulatta]
Length = 917
Score = 261 bits (667), Expect = 9e-68, Method: Composition-based stats.
Identities = 166/453 (36%), Positives = 255/453 (56%), Gaps = 23/453 (5%)
Query: 23 RAVKRDVAMAALTNQFTMSVES-MRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKR 81
+ + + +A+ LT + + V++ MR + Y L + GL +TVRMLP+YV
Sbjct: 468 KQIDKVLALFRLTREQLVDVQAKMRAELEYGLKKKSHGL----ATVRMLPTYVCGLPDGT 523
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA-VVDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F ALDLGGTNFRVL V + G V F IP ++G +LF I +
Sbjct: 524 EKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLGIMQGTGEELFDHIVQCIAD 583
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
++ + ++PLGFTFSFP Q +++G LI WTKGF +G DV+ +L+ A
Sbjct: 584 FLDYMGLK--GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIK 641
Query: 201 RVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R + +++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E ++ +
Sbjct: 642 RRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMED----MRNIEMVEG 697
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
IN E G F T++D ++D+ SLN G+Q EKM SGMYLGEI R+++
Sbjct: 698 DEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQIL 757
Query: 320 VHLSSINCL-PAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ L+ L + L RG FE++F I +DR+ LQ R+ +Q++ G+D + ED
Sbjct: 758 IDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQ-VRTILQQL-GLD-STCED 814
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPLVK-TQTQG----RATIAIDGSVFEKIPSFRRVL 433
++++VC V RAAQL + A + K + QG R T+ +DG++++ P F R+L
Sbjct: 815 SIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRIL 874
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAM 466
Q+ + L P CDV +L++DGSG GAA I+A+
Sbjct: 875 QETVKE-LAPRCDVTFMLSEDGSGKGAALITAV 906
Score = 222 bits (566), Expect = 5e-56, Method: Composition-based stats.
Identities = 157/440 (35%), Positives = 240/440 (54%), Gaps = 24/440 (5%)
Query: 40 MSVESMRQIMTYLLYEMVEGLE---GRESTVRMLPSYVYKADPKRATGVFYALDLGGTNF 96
+S +++ IM EM +GL + V+MLP++V G F +LDLGG+ F
Sbjct: 31 LSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFLSLDLGGSKF 90
Query: 97 RVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDL-NRT 153
RVL+V E V + + P + GN T+LF ++A + M+T+ DL ++
Sbjct: 91 RVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTK---DLKHKK 147
Query: 154 VPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGR-VSLKVNVVALC 212
+PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A R + V+++A+
Sbjct: 148 LPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDVDILAVV 207
Query: 213 NDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGN 272
NDTVGT+++ + DP +VGVIIGTG+NACY E S + D G IN E G
Sbjct: 208 NDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNI--DLVEGDEGRMC--INTEWGA 263
Query: 273 FDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAAL 332
F T+FD ++D SLN G+Q EKMISG+YLGE+ R +++ ++ L
Sbjct: 264 FGDDGALEDIRTEFDRELDLGSLNPGKQMFEKMISGLYLGELVRLILLKMAKAGLLFGGE 323
Query: 333 Q-TALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRG 391
+ +AL +G E+R + + GL TR + + G++ S D ++ VC +V
Sbjct: 324 KSSALHTKGKIETRHVAAMEKYK-EGLANTREILVDL-GLE-PSEADCIAVQHVCTIVSF 380
Query: 392 RAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECD 446
R+A L A+ A L K + R T+ +DG++++ P + + L + R L P CD
Sbjct: 381 RSANLCAAALAAILTRLRENKKVERLRTTVGVDGTLYKIHPQYPKRLH-KVVRKLVPSCD 439
Query: 447 VRAVLAKDGSGIGAAFISAM 466
VR +L++ GS GAA ++A+
Sbjct: 440 VRFLLSESGSTKGAAMVTAV 459
>emb|CAP36704.1| Hypothetical protein CBG19465 [Caenorhabditis briggsae]
Length = 494
Score = 261 bits (667), Expect = 9e-68, Method: Composition-based stats.
Identities = 167/459 (36%), Positives = 248/459 (54%), Gaps = 15/459 (3%)
Query: 22 VRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKR 81
V A RD+ A + +S + +R+IM + M +GL G+++ V+MLP+YV
Sbjct: 29 VVARPRDLIQEA-CERLVLSDQQLRRIMVLMEKSMEQGLSGKKAAVKMLPTYVDAVPNGT 87
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKT 141
G F ALDLGGTNFRVL + EG + F++P+ + G LF IA + K
Sbjct: 88 EKGDFLALDLGGTNFRVLHIKL-EGKETKMTGKIFRVPESIMRGTGEALFDHIADCMAKF 146
Query: 142 METRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQ-AAFG 200
ME +D + +PLGFTFSFP EQ + RG L+ WTKGF GV+G DV+ LL+ A
Sbjct: 147 MEENNLKDATK-LPLGFTFSFPCEQDGLTRGKLVTWTKGFKASGVEGADVVTLLRDACHR 205
Query: 201 RVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARG 260
R + ++VVAL NDTVGTL++ F++ Q+GVI+GTG+NACY E + K
Sbjct: 206 RKDIDIDVVALLNDTVGTLMACAFQENTCQIGVIVGTGTNACYMERLDRIPKLAGYVDEH 265
Query: 261 SALTP----INMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIAR 316
+ +TP IN E G F TK+D +D S+N GQ EKMISGMY+GE AR
Sbjct: 266 N-VTPEEMIINTEWGAFGDDGALSFLRTKWDDAVDRESINPGQHLYEKMISGMYMGECAR 324
Query: 317 RVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPG----LQFTRSTIQKVCGVD 372
V+ L+ L A+ F ++F I +D + Q T ++ + GV+
Sbjct: 325 VVLEDLAKQGLLFGGHSDAISTPHCFPTKFVSEIDSDLLEDDDRTFQKTYQILEDI-GVE 383
Query: 373 VQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRV 432
+ + D + VC L+ RAA L+A+ A L+ + T+ +DGSV+ P++ +
Sbjct: 384 MITANDCANVAYVCSLISTRAAHLTAA-GIAMLLNRINKKHVTVGVDGSVYRFHPTYPTL 442
Query: 433 LQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
L I ++ + + + +L++DGSG GAA ++A+ K
Sbjct: 443 LDAKIAELIVGDIEYKLMLSEDGSGRGAALVAAVATRLK 481
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
emb|CAC69958.1| hexokinase [Trypanosoma brucei] 647 0.0
ref|XP_822456.1| hexokinase [Trypanosoma brucei TREU927] >g... 645 0.0
ref|XP_822457.1| hexokinase [Trypanosoma brucei TREU927] >g... 637 0.0
gb|AAL93565.1|AF488830_1 hexokinase [Trypanosoma cruzi] >gi... 590 e-167
ref|XP_816463.1| hexokinase, putative [Trypanosoma cruzi st... 589 e-166
ref|XP_808992.1| hexokinase, putative [Trypanosoma cruzi st... 589 e-166
ref|XP_001564741.1| hexokinase, putative [Leishmania brazil... 570 e-161
ref|XP_001465336.1| hexokinase [Leishmania infantum JPCM5] ... 562 e-158
gb|AAT72300.1| hemoglobin receptor [Leishmania donovani] 561 e-158
ref|XP_001682958.1| hexokinase, putative [Leishmania major]... 561 e-158
ref|XP_001682957.1| hexokinase, putative [Leishmania major]... 560 e-157
ref|XP_001465335.1| hexokinase [Leishmania infantum JPCM5] ... 559 e-157
ref|XP_965673.2| hexokinase [Neurospora crassa OR74A] >gi|1... 550 e-155
ref|XP_749720.1| hexokinase Kxk [Aspergillus fumigatus Af29... 550 e-154
ref|XP_001260212.1| hexokinase Kxk, putative [Neosartorya f... 549 e-154
ref|XP_380676.1| hypothetical protein FG00500.1 [Gibberella... 549 e-154
gb|AAY83348.1| hexokinase [Hypocrea jecorina] 548 e-154
ref|XP_001912895.1| unnamed protein product [Podospora anse... 547 e-154
ref|XP_364444.1| hexokinase [Magnaporthe grisea 70-15] >gi|... 546 e-153
ref|XP_001597079.1| hypothetical protein SS1G_01273 [Sclero... 542 e-152
ref|XP_001247226.1| hexokinase [Coccidioides immitis RS] >g... 542 e-152
ref|XP_001275241.1| hexokinase Kxk, putative [Aspergillus c... 541 e-152
gb|ABY89285.1| putative hexokinase HXK1 [Gibberella monilif... 540 e-152
ref|XP_001386689.2| Hexokinase [Pichia stipitis CBS 6054] >... 540 e-152
ref|XP_001549109.1| hexokinase [Botryotinia fuckeliana B05.... 540 e-151
ref|XP_001850122.1| hexokinase [Culex pipiens quinquefascia... 539 e-151
ref|NP_079406.3| hexokinase domain containing 1 [Homo sapie... 539 e-151
dbj|BAF83713.1| unnamed protein product [Homo sapiens] 539 e-151
gb|AAH12337.1| HKDC1 protein [Homo sapiens] 538 e-151
ref|XP_001215959.1| hexokinase [Aspergillus terreus NIH2624... 538 e-151
ref|XP_001660030.1| hexokinase [Aedes aegypti] >gi|10887452... 537 e-151
ref|XP_001660031.1| hexokinase [Aedes aegypti] >gi|10887452... 537 e-151
ref|XP_001502742.1| PREDICTED: similar to hexokinase domain... 537 e-151
ref|XP_001819202.1| hypothetical protein [Aspergillus oryza... 537 e-151
gb|AAG28789.1|AF309088_1 hexokinase [Tuber borchii] 537 e-151
emb|CAH71500.1| hexokinase domain containing 1 [Homo sapiens] 537 e-151
ref|XP_001110556.1| PREDICTED: similar to hexokinase domain... 537 e-150
ref|XP_717405.1| hexokinase II [Candida albicans SC5314] >g... 536 e-150
ref|NP_524848.1| Hexokinase A CG3001-PA, isoform A [Drosoph... 535 e-150
sp|P17710|HXK1_MOUSE Hexokinase-1 (Hexokinase type I) (HK I... 535 e-150
ref|NP_034568.1| hexokinase 1 [Mus musculus] >gi|1850140|gb... 535 e-150
ref|NP_989543.1| hexokinase 2 [Gallus gallus] >gi|23821302|... 535 e-150
dbj|BAF83046.1| unnamed protein product [Homo sapiens] 535 e-150
gb|AAY24209.1| unknown [Homo sapiens] 535 e-150
gb|AAV32455.1| hexokinase [Leishmania infantum] 535 e-150
gb|EDL32103.1| hexokinase 1, isoform CRA_a [Mus musculus] 534 e-150
gb|AAA41334.1| hexokinase type II 534 e-150
ref|XP_870563.2| PREDICTED: similar to hexokinase II [Bos t... 534 e-150
ref|XP_001381777.1| PREDICTED: similar to hexokinase II [Mo... 534 e-150
ref|NP_000180.2| hexokinase 2 [Homo sapiens] >gi|56405344|s... 534 e-150
pdb|2NZT|A Chain A, Crystal Structure Of Human Hexokinase I... 534 e-150
ref|NP_038848.1| hexokinase 2 [Mus musculus] >gi|2495218|sp... 534 e-150
ref|XP_532991.2| PREDICTED: similar to hexokinase 2 [Canis ... 533 e-150
emb|CAA86511.1| Human hexokinase II cDNA [Homo sapiens] 533 e-150
gb|EDL92980.1| hexokinase 1, isoform CRA_a [Rattus norvegicus] 533 e-149
gb|EDL92983.1| hexokinase 1, isoform CRA_d [Rattus norvegicus] 533 e-149
ref|XP_421579.2| PREDICTED: similar to Hexokinase domain co... 533 e-149
gb|EDU44499.1| hexokinase [Pyrenophora tritici-repentis Pt-... 533 e-149
ref|XP_001110227.1| PREDICTED: similar to hexokinase 1 isof... 533 e-149
gb|EDL32105.1| hexokinase 1, isoform CRA_c [Mus musculus] 533 e-149
gb|EDL92981.1| hexokinase 1, isoform CRA_b [Rattus norvegicus] 533 e-149
ref|NP_036867.1| hexokinase 2 [Rattus norvegicus] >gi|12389... 533 e-149
gb|EDL92987.1| hexokinase 1, isoform CRA_h [Rattus norvegicus] 533 e-149
ref|XP_001162535.1| PREDICTED: hexokinase 2 isoform 2 [Pan ... 533 e-149
gb|EDL92989.1| hexokinase 1, isoform CRA_j [Rattus norvegicus] 533 e-149
gb|EDL32108.1| hexokinase 1, isoform CRA_f [Mus musculus] 533 e-149
gb|EDL92985.1| hexokinase 1, isoform CRA_f [Rattus norvegicus] 532 e-149
ref|NP_727350.1| Hexokinase A CG3001-PB, isoform B [Drosoph... 532 e-149
gb|EDL32107.1| hexokinase 1, isoform CRA_e [Mus musculus] 532 e-149
gb|EDL32104.1| hexokinase 1, isoform CRA_b [Mus musculus] 532 e-149
ref|XP_001111706.1| PREDICTED: similar to hexokinase 2 isof... 532 e-149
ref|XP_460972.1| hypothetical protein DEHA0F15169g [Debaryo... 532 e-149
dbj|BAE39552.1| unnamed protein product [Mus musculus] 532 e-149
ref|XP_001162408.1| PREDICTED: hexokinase 2 isoform 1 [Pan ... 532 e-149
ref|NP_663394.1| hexokinase domain containing 1 [Mus muscul... 532 e-149
gb|AAH72628.1| Hk1 protein [Mus musculus] >gi|148700159|gb|... 532 e-149
dbj|BAE36411.1| unnamed protein product [Mus musculus] 532 e-149
ref|NP_036866.1| hexokinase 1 [Rattus norvegicus] >gi|62266... 532 e-149
gb|EDL92984.1| hexokinase 1, isoform CRA_e [Rattus norvegicus] 532 e-149
gb|EDL92982.1| hexokinase 1, isoform CRA_c [Rattus norvegicus] 532 e-149
ref|XP_001111663.1| PREDICTED: similar to hexokinase 2 isof... 531 e-149
dbj|BAE25472.1| unnamed protein product [Mus musculus] 531 e-149
gb|EDL92990.1| hexokinase 1, isoform CRA_k [Rattus norvegicus] 531 e-149
gb|EDL92988.1| hexokinase 1, isoform CRA_i [Rattus norvegicus] 531 e-149
ref|XP_001110396.1| PREDICTED: similar to hexokinase 1 isof... 531 e-149
gb|AAA37804.1| hexokinase (EC 2.7.1.1) 531 e-149
gb|EDL92986.1| hexokinase 1, isoform CRA_g [Rattus norvegicus] 531 e-149
ref|XP_001169215.1| PREDICTED: hexokinase 1 isoform 8 [Pan ... 531 e-149
ref|XP_001110350.1| PREDICTED: similar to hexokinase 1 isof... 530 e-149
ref|XP_001110269.1| PREDICTED: similar to hexokinase 1 isof... 530 e-149
ref|XP_546137.2| PREDICTED: similar to hexokinase domain co... 530 e-149
gb|AAU05129.1| hexokinase [Aedes aegypti] 530 e-149
sp|Q5RC71|HXK1_PONPY Hexokinase-1 (Hexokinase type I) (HK I... 530 e-149
dbj|BAD92763.1| hexokinase 1 isoform HKI variant [Homo sapi... 530 e-149
ref|NP_001116459.1| hexokinase 2 [Sus scrofa] >gi|122134685... 530 e-149
gb|EAW54323.1| hexokinase 1, isoform CRA_d [Homo sapiens] 530 e-148
ref|NP_998231.1| hexokinase 2 [Danio rerio] >gi|28278945|gb... 530 e-148
emb|CAH65327.1| hypothetical protein [Gallus gallus] 529 e-148
gb|AAB91396.1| mutant type II hexokinase [Rattus norvegicus] 529 e-148
ref|XP_001364147.1| PREDICTED: similar to Hexokinase domain... 529 e-148
ref|NP_001096656.1| hexokinase I [Xenopus laevis] >gi|49114... 529 e-148
ref|XP_507830.2| PREDICTED: hexokinase 1 isoform 10 [Pan tr... 529 e-148
emb|CAH18060.1| hypothetical protein [Homo sapiens] 529 e-148
ref|XP_702631.1| PREDICTED: hypothetical protein [Danio rer... 529 e-148
ref|NP_277031.1| hexokinase 1 isoform HKI-R [Homo sapiens] ... 529 e-148
ref|NP_998417.1| hexokinase 1 [Danio rerio] >gi|28856173|gb... 529 e-148
pdb|1CZA|N Chain N, Mutant Monomer Of Recombinant Human Hex... 529 e-148
ref|XP_001169069.1| PREDICTED: hexokinase 1 isoform 2 [Pan ... 529 e-148
dbj|BAE26802.1| unnamed protein product [Mus musculus] 528 e-148
ref|XP_001169044.1| PREDICTED: hexokinase 1 isoform 1 [Pan ... 528 e-148
ref|NP_000179.2| hexokinase 1 isoform HKI [Homo sapiens] >g... 528 e-148
gb|AAQ02439.1| hexokinase 1 [synthetic construct] 528 e-148
ref|NP_277032.1| hexokinase 1 isoform HKI-ta/tb [Homo sapie... 528 e-148
ref|NP_001096201.1| hexokinase 1 [Xenopus tropicalis] >gi|1... 528 e-148
ref|XP_001169123.1| PREDICTED: hexokinase 1 isoform 4 [Pan ... 528 e-148
ref|NP_277035.2| hexokinase 1 isoform HKI-td [Homo sapiens] 528 e-148
gb|AAF82320.1|AAF82320 hexokinase 1 isoform td [Homo sapien... 528 e-148
gb|AAS60194.1| hexokinase 3 [Nicotiana tabacum] 528 e-148
gb|AAG18422.1|AF288471_1 hexokinase I [Xenopus laevis] 528 e-148
emb|CAA86476.2| hexokinase II [Homo sapiens] 527 e-148
dbj|BAF84701.1| unnamed protein product [Homo sapiens] 527 e-148
gb|AAG28503.1|AF196966_1 hexokinase [Citrus sinensis] 527 e-148
ref|XP_536376.2| PREDICTED: similar to Hexokinase, type I (... 527 e-148
gb|AAP40021.1| hexokinase [Nicotiana benthamiana] 527 e-148
emb|CAA47379.1| hexokinase type 1 [Homo sapiens] 527 e-147
pdb|1HKC|A Chain A, Recombinant Human Hexokinase Type I Com... 527 e-147
gb|AAF28854.1| hexokinase I [Cyprinus carpio] 527 e-147
pdb|1DGK|N Chain N, Mutant Monomer Of Recombinant Human Hex... 527 e-147
gb|ABA01010.1| hexokinase [Solanum chacoense] 527 e-147
sp|Q9SQ76|HXK2_SOLTU Hexokinase-2 (StHK2) >gi|6492118|gb|AA... 526 e-147
gb|AAS60192.1| hexokinase 1a [Nicotiana tabacum] 526 e-147
gb|AAV32456.1| hexokinase [Leishmania mexicana] 526 e-147
gb|AAT77513.1| hexokinase 3 [Nicotiana sylvestris] 526 e-147
emb|CAC81350.1| hexokinase [Solanum lycopersicum] 526 e-147
ref|NP_985826.1| AFR279Cp [Ashbya gossypii ATCC 10895] >gi|... 526 e-147
ref|XP_001355083.1| GA15574-PA [Drosophila pseudoobscura] >... 526 e-147
ref|NP_989432.1| hexokinase 1 [Gallus gallus] >gi|23821300|... 526 e-147
gb|AAA52646.1| hexokinase 1 [Homo sapiens] 526 e-147
ref|XP_001525198.1| hexokinase [Lodderomyces elongisporus N... 525 e-147
ref|XP_970645.1| PREDICTED: similar to CG3001-PA, isoform A... 525 e-147
gb|AAG35735.1|AF208543_1 hexokinase [Lycopersicon esculentum] 525 e-147
gb|AAU05128.1| hexokinase [Aedes albopictus] 525 e-147
ref|XP_001400569.1| hexokinase hxk-Aspergillus niger >gi|41... 525 e-147
gb|AAT77515.1| hexokinase 7 [Nicotiana tabacum] 524 e-147
ref|NP_001075245.1| hexokinase II [Equus caballus] >gi|1463... 523 e-147
gb|AAH21278.1| HKDC1 protein [Homo sapiens] 523 e-147
ref|XP_001498596.1| PREDICTED: similar to Hexokinase 3 (whi... 523 e-146
ref|NP_001012686.1| hexokinase 1 [Bos taurus] >gi|33332343|... 522 e-146
ref|XP_546212.2| PREDICTED: similar to Hexokinase type III ... 522 e-146
gb|AAY60841.1| hexokinase [Solanum lycopersicum] 522 e-146
ref|XP_680728.1| hypothetical protein AN7459.2 [Aspergillus... 522 e-146
ref|XP_453567.1| HXK_KLULA [Kluyveromyces lactis] >gi|38605... 522 e-146
ref|NP_592948.1| hexokinase 1 (PMID 8549830) [Schizosacchar... 522 e-146
emb|CAP36704.1| Hypothetical protein CBG19465 [Caenorhabdit... 522 e-146
gb|ABS89272.1| hexokinase 1a [Gadus morhua] 522 e-146
ref|XP_001380968.1| PREDICTED: similar to Hexokinase 3 (whi... 521 e-146
ref|NP_194642.1| ATHXK1 (GLUCOSE INSENSITIVE 2); ATP bindin... 521 e-146
sp|Q9SEK2|HXK1_TOBAC Hexokinase-1 (NtHxK1) >gi|6594674|gb|A... 521 e-146
ref|XP_518124.2| PREDICTED: hexokinase 3 isoform 2 [Pan tro... 520 e-146
ref|NP_776744.1| FK506 binding protein 12-rapamycin associa... 520 e-146
gb|ABS89273.1| hexokinase 1b [Gadus morhua] 520 e-146
gb|AAV91306.1| hexokinase A [Drosophila santomea] >gi|56428... 520 e-145
ref|XP_001255832.1| PREDICTED: similar to hexokinase II, pa... 520 e-145
gb|AAL60584.1|AF454962_1 hexokinase [Brassica oleracea] 520 e-145
emb|CAA43855.1| hexakinase [Kluyveromyces lactis] 520 e-145
gb|AAA34697.1| hexokinase P-II peptide >gi|224664|prf||1110... 519 e-145
ref|XP_001137121.1| PREDICTED: hexokinase 3 isoform 1 [Pan ... 519 e-145
emb|CAO65442.1| unnamed protein product [Vitis vinifera] 519 e-145
sp|Q9SEK3|HXK1_SPIOL Hexokinase-1 (SoHxK1) >gi|6594672|gb|A... 519 e-145
gb|AAI00649.1| Hexokinase 3 [Rattus norvegicus] >gi|1490398... 518 e-145
ref|NP_001090603.1| hypothetical protein LOC100036846 [Xeno... 518 e-145
gb|AAA34699.1| hexokinase (HXK2) 518 e-145
gb|AAH28129.1| Hexokinase 3 (white cell) [Homo sapiens] >gi... 518 e-145
gb|AAX43272.1| hexokinase 3 [synthetic construct] 518 e-145
emb|CAF90567.1| unnamed protein product [Tetraodon nigrovir... 518 e-145
ref|NP_001120545.1| hypothetical protein LOC100145699 [Xeno... 517 e-145
ref|NP_002106.1| hexokinase 3 [Homo sapiens] >gi|1708363|sp... 517 e-145
emb|CAN83149.1| hypothetical protein [Vitis vinifera] 517 e-144
ref|NP_179576.1| ATHXK2 (HEXOKINASE 2); ATP binding / hexok... 517 e-144
ref|NP_001108597.1| hexokinase domain containing 1 [Danio r... 516 e-144
ref|XP_001520120.1| PREDICTED: similar to glucokinase [Orni... 515 e-144
ref|XP_001086179.1| PREDICTED: hexokinase 3 [Macaca mulatta] 515 e-144
gb|AAS60197.1| hexokinase 5 [Nicotiana tabacum] 515 e-144
ref|XP_001487588.1| hypothetical protein PGUG_00965 [Pichia... 515 e-144
ref|XP_001333260.1| PREDICTED: similar to Hexokinase domain... 515 e-144
gb|AAO24584.1| At2g19860 [Arabidopsis thaliana] >gi|1107436... 515 e-144
gb|EAW99603.1| hexokinase 2, isoform CRA_b [Homo sapiens] 515 e-144
dbj|BAE42341.1| unnamed protein product [Mus musculus] >gi|... 514 e-144
gb|EDL94016.1| hexokinase 3, isoform CRA_b [Rattus norvegicus] 514 e-144
ref|NP_071515.1| hexokinase 3 [Rattus norvegicus] >gi|12389... 514 e-144
gb|AAI17862.1| Hk3 protein [Mus musculus] 514 e-144
ref|NP_001028417.1| hexokinase 3 [Mus musculus] >gi|8328824... 513 e-144
dbj|BAE37000.1| unnamed protein product [Mus musculus] 513 e-144
dbj|BAE29220.1| unnamed protein product [Mus musculus] 513 e-143
dbj|BAE42045.1| unnamed protein product [Mus musculus] 513 e-143
dbj|BAE24390.1| unnamed protein product [Mus musculus] >gi|... 513 e-143
ref|NP_001021106.1| F14B4.2a [Caenorhabditis elegans] >gi|3... 512 e-143
gb|AAS60196.1| hexokinase 4b [Nicotiana tabacum] 512 e-143
sp|P50506|HXK_DEBOC Hexokinase >gi|1041966|gb|AAB34892.1| h... 512 e-143
gb|AAL60583.1|AF454961_1 hexokinase [Brassica oleracea] 512 e-143
emb|CAG09720.1| unnamed protein product [Tetraodon nigrovir... 512 e-143
gb|AAS60195.1| hexokinase 4a [Nicotiana tabacum] 512 e-143
ref|XP_001754148.1| hexokinase protein HXK7 [Physcomitrella... 511 e-143
ref|NP_001021107.1| F14B4.2b [Caenorhabditis elegans] >gi|5... 510 e-143
gb|AAI17861.1| Hk3 protein [Mus musculus] 510 e-143
ref|XP_001380610.1| PREDICTED: similar to hexokinase 1, [Mo... 510 e-142
dbj|BAE35470.1| unnamed protein product [Mus musculus] >gi|... 509 e-142
ref|XP_001899820.1| Hexokinase family protein [Brugia malay... 509 e-142
dbj|BAE29007.1| unnamed protein product [Mus musculus] 508 e-142
ref|NP_001044214.1| Os01g0742500 [Oryza sativa (japonica cu... 507 e-142
emb|CAO45811.1| unnamed protein product [Vitis vinifera] 506 e-141
gb|AAV88622.1| hexokinase [Leishmania donovani] 506 e-141
emb|CAJ28915.1| hexokinase [Crassostrea gigas] 506 e-141
ref|XP_001379711.1| PREDICTED: similar to glucokinase [Mono... 505 e-141
emb|CAG05684.1| unnamed protein product [Tetraodon nigrovir... 505 e-141
ref|XP_001784334.1| hexokinase protein HXK3 [Physcomitrella... 504 e-141
gb|AAA60333.1| hexokinase [Arabidopsis thaliana] >gi|158238... 504 e-141
ref|XP_001752229.1| hexokinase protein HXK8 [Physcomitrella... 504 e-141
ref|XP_966410.1| PREDICTED: similar to CG3001-PA, isoform A... 503 e-141
ref|NP_011261.1| Hexokinase isoenzyme 2 that catalyzes phos... 501 e-140
ref|XP_001265599.1| hexokinase [Neosartorya fischeri NRRL 1... 501 e-140
ref|XP_975828.1| PREDICTED: similar to CG3001-PA, isoform A... 499 e-139
gb|AAG22922.1|AF257605_2 hexokinase-t2 [Drosophila melanoga... 499 e-139
gb|EAY75659.1| hypothetical protein OsI_003506 [Oryza sativ... 499 e-139
gb|AAG22924.1|AF257606_2 hexokinase-t2 [Drosophila melanoga... 499 e-139
gb|AAG22908.1|AF257598_2 hexokinase-t2 [Drosophila melanoga... 499 e-139
ref|NP_001096321.1| hypothetical protein LOC100124905 [Xeno... 498 e-139
ref|XP_001784630.1| hexokinase protein HXK2 [Physcomitrella... 498 e-139
gb|AAG22918.1|AF257603_2 hexokinase-t2 [Drosophila melanoga... 498 e-139
gb|AAG22896.1|AF257592_2 hexokinase-t2 [Drosophila melanoga... 498 e-139
gb|AAG22892.1|AF257590_2 hexokinase-t2 [Drosophila melanoga... 498 e-139
ref|XP_001360104.1| GA20820-PA [Drosophila pseudoobscura] >... 498 e-139
ref|XP_444978.1| hypothetical protein CAGL0A04829g [Candida... 498 e-139
emb|CAA27203.1| unnamed protein product [Saccharomyces cere... 498 e-139
ref|XP_001143661.1| PREDICTED: glucokinase isoform 3 [Pan t... 498 e-139
gb|EDN59204.1| hexokinase I (PI) (also called hexokinase A)... 498 e-139
ref|NP_116711.1| Hexokinase isoenzyme 1, a cytosolic protei... 497 e-139
gb|AAP36837.1| Homo sapiens glucokinase (hexokinase 4, matu... 497 e-139
ref|NP_000153.1| glucokinase isoform 1 [Homo sapiens] >gi|5... 497 e-139
ref|XP_001878887.1| hexokinase [Laccaria bicolor S238N-H82]... 497 e-139
ref|NP_733151.2| Hex-t2 CG32849-PA [Drosophila melanogaster... 497 e-138
ref|NP_034422.2| glucokinase [Mus musculus] >gi|1708365|sp|... 496 e-138
gb|ABS31137.1| glucokinase [Homo sapiens] 496 e-138
emb|CAA27202.1| unnamed protein product [Saccharomyces cere... 495 e-138
ref|XP_001143302.1| PREDICTED: glucokinase isoform 1 [Pan t... 495 e-138
gb|AAL13623.1| GH15883p [Drosophila melanogaster] 495 e-138
ref|NP_001079298.1| glucokinase [Xenopus laevis] >gi|126284... 495 e-138
gb|AAB59563.1| glucokinase 495 e-138
ref|NP_277043.1| glucokinase isoform 3 [Homo sapiens] >gi|2... 495 e-138
sp|P17712|HXK4_RAT Glucokinase (Hexokinase-4) (Hexokinase t... 494 e-138
ref|NP_001095772.1| glucokinase [Bos taurus] >gi|151554675|... 494 e-138
gb|AAG22928.1|AF257608_2 hexokinase-t2 [Drosophila melanoga... 494 e-138
ref|XP_975717.1| PREDICTED: similar to CG3001-PA, isoform A... 494 e-138
ref|XP_001898658.1| hexokinase [Brugia malayi] >gi|15859392... 493 e-137
sp|Q2KNB7|HXK9_ORYSJ Hexokinase-9 (Hexokinase-5) >gi|621307... 493 e-137
sp|Q2KNB9|HXK2_ORYSJ Hexokinase-2 (Hexokinase-3) >gi|621307... 493 e-137
ref|NP_001077423.1| glucokinase [Felis catus] >gi|125434898... 493 e-137
gb|AAG21973.1|AF257652_2 hexokinase-t2 [Drosophila yakuba] 493 e-137
ref|XP_001093035.1| PREDICTED: similar to glucokinase isofo... 492 e-137
ref|XP_501216.1| hypothetical protein [Yarrowia lipolytica]... 492 e-137
gb|EEH38094.1| hexokinase [Paracoccidioides brasiliensis Pb01] 492 e-137
ref|XP_001143590.1| PREDICTED: glucokinase isoform 2 [Pan t... 492 e-137
gb|EEH47729.1| hexokinase [Paracoccidioides brasiliensis Pb18] 492 e-137
gb|AAG22956.1|AF257643_2 hexokinase-t2 [Drosophila simulans... 491 e-137
gb|AAG22944.1|AF257637_2 hexokinase-t2 [Drosophila simulans... 491 e-137
ref|XP_001766433.1| hexokinase protein HXK5 [Physcomitrella... 491 e-137
pdb|1V4T|A Chain A, Crystal Structure Of Human Glucokinase 491 e-137
pdb|1V4S|A Chain A, Crystal Structure Of Human Glucokinase 491 e-137
ref|NP_277042.1| glucokinase isoform 2 [Homo sapiens] >gi|2... 491 e-137
ref|XP_001092919.1| PREDICTED: similar to glucokinase isofo... 491 e-137
gb|EAY98804.1| hypothetical protein OsI_020037 [Oryza sativ... 491 e-137
gb|AAA34698.1| hexokinase (HXK1) 490 e-137
ref|XP_749181.1| hexokinase [Aspergillus fumigatus Af293] >... 490 e-137
gb|AAC42074.1| glucokinase >gi|15029832|gb|AAH11139.1| Gck ... 490 e-137
gb|AAC33587.2| glucokinase [Cyprinus carpio] 490 e-136
ref|XP_001837942.1| hypothetical protein CC1G_11986 [Coprin... 490 e-136
emb|CAG05683.1| unnamed protein product [Tetraodon nigrovir... 490 e-136
gb|AAG22954.1|AF257642_2 hexokinase-t2 [Drosophila simulans... 490 e-136
ref|NP_036697.1| glucokinase [Rattus norvegicus] >gi|56240|... 488 e-136
ref|XP_759240.1| hypothetical protein UM03093.1 [Ustilago m... 488 e-136
emb|CAN74362.1| hypothetical protein [Vitis vinifera] 488 e-136
ref|XP_001772444.1| hexokinase protein HXK1 [Physcomitrella... 488 e-136
ref|XP_001495888.1| PREDICTED: similar to glucokinase [Equu... 487 e-136
ref|NP_001117721.1| glucokinase [Oncorhynchus mykiss] >gi|7... 487 e-135
ref|XP_747854.1| glucokinase GlkA [Aspergillus fumigatus Af... 486 e-135
gb|AAC33585.2| glucokinase [Sparus aurata] 486 e-135
gb|AAQ72424.1| hexokinase PpHxk1 [Physcomitrella patens] >g... 485 e-135
gb|AAF40309.1|AF169368_1 glucokinase [Sparus aurata] 485 e-135
ref|XP_681958.1| HXKG_ASPNG GLUCOKINASE (GLUCOSE KINASE) (G... 485 e-135
ref|XP_001762951.1| hexokinase protein HXK6 [Physcomitrella... 485 e-135
emb|CAG08582.1| unnamed protein product [Tetraodon nigrovir... 485 e-135
gb|AAC50422.1| ATP:D-hexose 6-phosphotransferase 485 e-135
dbj|BAD92188.1| Hexokinase 3 variant [Homo sapiens] 485 e-135
ref|XP_001605294.1| PREDICTED: similar to ENSANGP0000002836... 485 e-135
ref|XP_001643699.1| hypothetical protein Kpol_507p3 [Vander... 485 e-135
gb|AAG23108.1|AF257584_1 hexokinase-C [Drosophila melanogas... 484 e-135
gb|AAG23076.1|AF257552_1 hexokinase-C [Drosophila melanogas... 484 e-135
ref|NP_524674.1| Hexokinase C CG8094-PA [Drosophila melanog... 484 e-135
ref|XP_001110189.1| PREDICTED: similar to hexokinase 1 isof... 484 e-135
gb|AAG22929.1|AF257623_1 hexokinase-C [Drosophila simulans]... 483 e-134
Sequences not found previously or not previously below threshold:
>emb|CAC69958.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 647 bits (1670), Expect = 0.0, Method: Composition-based stats.
Identities = 470/471 (99%), Positives = 470/471 (99%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLF FIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFDFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
>ref|XP_822456.1| hexokinase [Trypanosoma brucei TREU927]
gb|EAN77628.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 645 bits (1665), Expect = 0.0, Method: Composition-based stats.
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
>ref|XP_822457.1| hexokinase [Trypanosoma brucei TREU927]
gb|EAN77629.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 637 bits (1644), Expect = 0.0, Method: Composition-based stats.
Identities = 460/471 (97%), Positives = 465/471 (98%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLF FIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFDFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTV T+ISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVATMISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPI+MESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPISMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAK GSG+GAA ISA+V + K
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKGGSGVGAALISAIVADGK 471
>gb|AAL93565.1|AF488830_1 hexokinase [Trypanosoma cruzi]
emb|CAD26835.1| hexokinase [Trypanosoma cruzi]
Length = 471
Score = 590 bits (1523), Expect = e-167, Method: Composition-based stats.
Identities = 315/471 (66%), Positives = 385/471 (81%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MS RLNN+L+HI+++ D +T+R +K+ +A+A+L NQFT+ + ++Q+M Y++++M+EGL
Sbjct: 1 MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHQMIEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGREST+RMLPSYVYK DP +ATGVFYALDLGGTNFRVLRV CKEG V D + F IP+
Sbjct: 61 EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL+G A DLFGFIA +VKK ME +APEDLNRTVPLGFTFSFP EQ V+ G LI+WTKG
Sbjct: 121 QALQGTAEDLFGFIAQSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDHGFLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FST+GV+G DV+ LLQ A R+ +KV VVALCNDTVGTLI++YF DP+ QVGVIIGTGSN
Sbjct: 181 FSTRGVEGKDVVELLQKALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE A AVTK+P+VAARG+ TPINME GNFDSKY+FVLP T +D +D + N+ Q
Sbjct: 241 ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNFQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EKM+SGMYLGEI+RR+I HL+ ++CLP+AL + + SFE++F GMISADRMPGLQF
Sbjct: 301 TQEKMVSGMYLGEISRRMIAHLAELHCLPSALASKMAKPWSFETKFMGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR Q++ VDV + DL +IRDVC LVRGRAAQ+SA FC APLVKT+ +GRAT+AIDG
Sbjct: 361 TRQVFQELFQVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEK PSFRR+LQ N+N ILGP CDV LA+DGSGIGAAFISA+VVNDK
Sbjct: 421 SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK 471
>ref|XP_816463.1| hexokinase, putative [Trypanosoma cruzi strain CL Brener]
gb|EAN94612.1| hexokinase, putative [Trypanosoma cruzi]
Length = 471
Score = 589 bits (1520), Expect = e-166, Method: Composition-based stats.
Identities = 316/471 (67%), Positives = 385/471 (81%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MS RLNN+L+HI+++ D +T+R +K+ +A+A+L NQFT+ + ++Q+M Y+++EM+EGL
Sbjct: 1 MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHEMIEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGREST+RMLPSYVYK DP +ATGVFYALDLGGTNFRVLRV CKEG V D + F IP+
Sbjct: 61 EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL+G A DLFGFIA +VKK ME +APEDLNRTVPLGFTFSFP EQ V+ G LI+WTKG
Sbjct: 121 QALQGTAEDLFGFIAQSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDHGFLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FST+GV+G DV+ LLQ A R+ +KV VVALCNDTVGTLI++YF DP+ QVGVIIGTGSN
Sbjct: 181 FSTRGVEGKDVVELLQKALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE A AVTK+P+VAARG+ TPINME GNFDSKY+FVLP T +D +D + N+ Q
Sbjct: 241 ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNYQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EKM+SGMYLGEI+RR+I HL+ ++CLP+AL + + SFE++F GMISADRMPGLQF
Sbjct: 301 TQEKMVSGMYLGEISRRMIAHLAELHCLPSALASKMAKPWSFETKFMGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR Q++ VDV + DL +IRDVC LVRGRAAQ+SA FC APLVKT+ +GRAT+AIDG
Sbjct: 361 TRQVFQELFHVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEK PSFRR+LQ N+N ILGP CDV LA+DGSGIGAAFISA+VVNDK
Sbjct: 421 SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK 471
>ref|XP_808992.1| hexokinase, putative [Trypanosoma cruzi strain CL Brener]
gb|EAN87141.1| hexokinase, putative [Trypanosoma cruzi]
Length = 471
Score = 589 bits (1518), Expect = e-166, Method: Composition-based stats.
Identities = 316/471 (67%), Positives = 385/471 (81%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MS RLNN+L+HI+++ D +T+R +K+ +A+A+L NQFT+ + ++Q+M Y+++EM+EGL
Sbjct: 1 MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHEMIEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGREST+RMLPSYVYK DP +ATGVFYALDLGGTNFRVLRV CKEG V D + F IP+
Sbjct: 61 EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL+G A DLFGFIA +VKK ME +APEDLNRTVPLGFTFSFP EQ V+ G LI+WTKG
Sbjct: 121 QALQGTAEDLFGFIAKSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDNGFLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FST+GV+G DV+ LLQ A R+ +KV VVALCNDTVGTLI++YF DP+ QVGVIIGTGSN
Sbjct: 181 FSTRGVEGKDVVELLQNALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE A AVTK+P+VAARG+ TPINME GNFDSKY+FVLP T +D +D + N+ Q
Sbjct: 241 ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNYQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EKM+SGMYLGEI+RR+I HL+ + CLP+AL + + SFE++F GMISADRMPGLQF
Sbjct: 301 TQEKMVSGMYLGEISRRMIAHLAELRCLPSALASKMAKPWSFETKFMGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR +Q++ VDV + DL +IRDVC LVRGRAAQ+SA FC APLVKT+ +GRAT+AIDG
Sbjct: 361 TRQVLQELFHVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEK PSFRR+LQ N+N ILGP CDV LA+DGSGIGAAFISA+VVNDK
Sbjct: 421 SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK 471
>ref|XP_001564741.1| hexokinase, putative [Leishmania braziliensis MHOM/BR/75/M2904]
emb|CAM38811.1| hexokinase, putative [Leishmania braziliensis]
Length = 471
Score = 570 bits (1470), Expect = e-161, Method: Composition-based stats.
Identities = 286/471 (60%), Positives = 367/471 (77%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN++ H++I+ +D E +R +K+ +A+A+L+ QFTM+ E M+Q+ Y++YEMVEGL
Sbjct: 1 MASRVNNLMNHLAIRDSDSEEMRYIKQRLALASLSTQFTMASEKMKQLTMYMVYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPSYVY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D S F IPK
Sbjct: 61 EGRPSTVRMLPSYVYTSDPAKATGVYYALDLGGTNFRVLRVSLRSGKVDDRIDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL GN+ +LF FIA +VKK M APEDL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALTGNSANLFDFIAQSVKKMMSENAPEDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQ + R+ + VNVVALCNDTVGTL++ YF D QVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQGSLRRMHINVNVVALCNDTVGTLVARYFVDTNAQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV ARG+A+TPINME GNFDSKY++ LPTT +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVCARGNAVTPINMECGNFDSKYKYALPTTVYDDEMDAITPNRDHQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L LG +FES+ GM++AD+MPGLQF
Sbjct: 301 RQEKIVSGMYLGEISRRMIVHLAQLGCLPRDLVDGLGKPWAFESKHMGMVAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I++V GV+V + DL IR++C LVR RAAQ +A AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRVAGVNVTDVADLHTIREICCLVRNRAAQQAAVLSAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK+PSF+R+ Q+ I ILGP + + VL KDGSG+GAA I A+ N K
Sbjct: 421 SVYEKVPSFQRLYQECITGILGPTSNAKVVLQKDGSGVGAAMICALAANQK 471
>ref|XP_001465336.1| hexokinase [Leishmania infantum JPCM5]
emb|CAM67757.1| hexokinase, putative [Leishmania infantum]
Length = 471
Score = 562 bits (1448), Expect = e-158, Method: Composition-based stats.
Identities = 291/471 (61%), Positives = 368/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MATRVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVDV + DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDVTDMSDLHTIREACCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL KDGSG+GAA I A+ N K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQKDGSGVGAAMICALAANKK 471
>gb|AAT72300.1| hemoglobin receptor [Leishmania donovani]
Length = 471
Score = 561 bits (1447), Expect = e-158, Method: Composition-based stats.
Identities = 291/471 (61%), Positives = 369/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+++ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MATRVNNLLSHIALRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVDV + DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDVTDMSDLHTIRETCCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL KDGSG+GAA I A+ VN K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQKDGSGVGAAMICALAVNKK 471
>ref|XP_001682958.1| hexokinase, putative [Leishmania major]
emb|CAJ03835.1| hexokinase, putative [Leishmania major]
Length = 471
Score = 561 bits (1447), Expect = e-158, Method: Composition-based stats.
Identities = 291/471 (61%), Positives = 369/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MAARVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVD+ I DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDMADISDLHTIRETCCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL +DGSG+GAA I A+ VN K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQRDGSGVGAAMICALAVNTK 471
>ref|XP_001682957.1| hexokinase, putative [Leishmania major]
gb|AAV32454.1| hexokinase [Leishmania major]
emb|CAJ03833.1| hexokinase, putative [Leishmania major]
Length = 471
Score = 560 bits (1443), Expect = e-157, Method: Composition-based stats.
Identities = 290/471 (61%), Positives = 368/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MAARVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVD+ I DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDMADISDLHTIRETCCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL +DGSG+GAA I A+ N K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQRDGSGVGAAMICALAANTK 471
>ref|XP_001465335.1| hexokinase [Leishmania infantum JPCM5]
emb|CAM67756.1| hexokinase, putative [Leishmania infantum]
Length = 471
Score = 559 bits (1442), Expect = e-157, Method: Composition-based stats.
Identities = 290/471 (61%), Positives = 368/471 (78%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
M+ R+NN+L HI+I+ +D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGL
Sbjct: 1 MATRVNNLLSHIAIRDSDSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGR STVRMLPS+VY +DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK
Sbjct: 61 EGRPSTVRMLPSFVYTSDPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL G+ATDLF FIA +VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKG
Sbjct: 121 SALVGDATDLFDFIAQSVKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTK V+GNDV+ LLQA+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSN
Sbjct: 181 FSTKNVEGNDVVELLQASLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE ASAVTKDPAV+ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q
Sbjct: 241 ACYFERASAVTKDPAVSARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EK++SGMYLGEI+RR+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQF
Sbjct: 301 RQEKLVSGMYLGEISRRLIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR I+++ GVDV + DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DG
Sbjct: 361 TRELIKRIAGVDVTDMSDLHTIREACCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SV+EK PSF+R+ Q+ I ILG +V+ VL +DGSG+GAA I A+ N K
Sbjct: 421 SVYEKTPSFQRLYQECITSILGSTSNVKVVLQRDGSGVGAAMICALAANKK 471
>ref|XP_965673.2| hexokinase [Neurospora crassa OR74A]
gb|EAA36437.2| hexokinase [Neurospora crassa OR74A]
Length = 489
Score = 550 bits (1418), Expect = e-155, Method: Composition-based stats.
Identities = 151/458 (32%), Positives = 239/458 (52%), Gaps = 16/458 (3%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGV 85
+ L FT+ ++++ + ++E+ +GL + ++ M P++V TG
Sbjct: 12 DLRNEIEHLERLFTVDGAKLKEVTNHFVHELEKGLSVQGGSIPMNPTWVMSFPDGNETGT 71
Query: 86 FYALDLGGTNFRVLRVACKE-GAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMET 144
+ ALD+GGTN RV +V E + D S +++P+ G+A +L+ +IA + + +ET
Sbjct: 72 YLALDMGGTNLRVCQVTLTETKSEFDIIQSKYRMPEELKTGDAEELWEYIADCLMQFIET 131
Query: 145 RAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS 203
+ +PLGFTFS+P Q ++ G+L RWTKGF GV+G++V+ + +AA R
Sbjct: 132 HHGDPTKLDALPLGFTFSYPATQNYIDEGILQRWTKGFDIAGVEGHNVVPMFEAALQRRG 191
Query: 204 LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSAL 263
+ + + AL NDT GTLI+ + DP++++G I GTG NA Y E ++ K +
Sbjct: 192 VPIKLTALINDTTGTLIASAYTDPKMRIGCIFGTGCNAAYMENCGSIPKLAHMNLPPDMP 251
Query: 264 TPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLS 323
IN E G FD++++ VLP T +D+ ID S GQQ+ EKM++G+YLGEI R V+V L
Sbjct: 252 MAINCEWGAFDNEHK-VLPRTPYDVIIDKDSPRPGQQSFEKMVAGLYLGEIFRLVLVDLH 310
Query: 324 ---SINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLR 380
I P L S +S F +I D L T Q G+ + +L
Sbjct: 311 DNQEIKIFPGQDIAKLRKAYSLDSSFLSLIEEDPFENLSETFELFQTKLGL-TPTGPELE 369
Query: 381 IIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRI 440
+IR L+ RAA+LSA A K + + + DGSVF K P+F+ + I
Sbjct: 370 LIRRTAELIGTRAARLSACGVAAI-SKKKGYKQCHVGADGSVFNKYPNFKARGAQALREI 428
Query: 441 LGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
L + + + A+DGSG+GAA I+A+ +
Sbjct: 429 LDWPEKADPKEDDPIEILAAEDGSGVGAALIAALTMQR 466
>ref|XP_749720.1| hexokinase Kxk [Aspergillus fumigatus Af293]
gb|EAL87682.1| hexokinase Kxk, putative [Aspergillus fumigatus Af293]
gb|EDP54242.1| hexokinase Kxk, putative [Aspergillus fumigatus A1163]
Length = 490
Score = 550 bits (1417), Expect = e-154, Method: Composition-based stats.
Identities = 152/464 (32%), Positives = 236/464 (50%), Gaps = 13/464 (2%)
Query: 17 NDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V +++ + FT+ ++Q++ + + E+ +GL + M ++V
Sbjct: 11 SRKGSMADVPQNLLQQIKDFEEMFTVDKAKLKQVVDHFVKELDKGLSVEGGNIPMNVTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
G F ALD+GGTN RV + +E D S +++P+ G A +L+ +
Sbjct: 71 MGFPDGDEQGTFLALDMGGTNLRVCEITLTEEKGGFDICQSKYRMPEELKTGTAEELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ +E E+ ++PLGFTFS+P Q ++ G+L RWTKGF GV+G DV+
Sbjct: 131 IADCIQQFIEFHHGEEGLTSLPLGFTFSYPATQEYIDHGILQRWTKGFDIDGVEGQDVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
L+ R L + V AL NDT GTLI+ + DPE+++G I GTG NA Y E +V K
Sbjct: 191 PLEETLKRKGLPIKVAALINDTTGTLIASAYTDPEMKIGCIFGTGVNAAYMENVGSVPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
+ IN E G FD+++ VLP TK+D ID S GQQA EKM +G+YLGE
Sbjct: 251 AHMNLPPDMPVAINCEYGAFDNEH-VVLPLTKYDHIIDRDSPRPGQQAFEKMTAGLYLGE 309
Query: 314 IARRVIVHL--SSINCLPAALQT-ALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
I R ++ L S + T L ++ F I D LQ T+ ++
Sbjct: 310 IFRLALIDLLDSRPGLIFQNQDTSKLRKPYLLDASFLAAIEEDPYENLQETQELFERELN 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ ++ +L +IR + L+ RAA+LSA A K + + DGSVF K P F+
Sbjct: 370 IK-PTLAELEMIRRLAELIGTRAARLSACGVAAI-CKKKNIESCHVGADGSVFTKYPHFK 427
Query: 431 RVLQDNINRILGP----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ IL + V + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAQALREILDWAPNEKDKVTIMAAEDGSGVGAALIAALTLKR 471
>ref|XP_001260212.1| hexokinase Kxk, putative [Neosartorya fischeri NRRL 181]
gb|EAW18315.1| hexokinase Kxk, putative [Neosartorya fischeri NRRL 181]
Length = 490
Score = 549 bits (1416), Expect = e-154, Method: Composition-based stats.
Identities = 153/464 (32%), Positives = 236/464 (50%), Gaps = 13/464 (2%)
Query: 17 NDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V +++ + FT+ ++Q++ + + E+ +GL + M ++V
Sbjct: 11 SRKGSMADVPQNLLQQIKDFEEMFTVDRAKLKQVVDHFVKELEKGLSVEGGNIPMNVTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
G F ALD+GGTN RV + +E D S +++P+ G A +L+ +
Sbjct: 71 MDFPDGDEQGTFLALDMGGTNLRVCEITLTEEKGGFDICQSKYRMPEELKSGTAEELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ +E E+ ++PLGFTFS+P Q ++ GVL RWTKGF GV+G DV+
Sbjct: 131 IADCIQQFIEFHHGEEGLTSLPLGFTFSYPATQEYIDHGVLQRWTKGFDIDGVEGQDVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
L+ R L + V AL NDT GTLI+ + DPE+++G I GTG NA Y E +V K
Sbjct: 191 PLEETLKRKGLPIKVAALINDTTGTLIASAYTDPEMKIGCIFGTGVNAAYMEDVGSVPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
+ IN E G FD+++ VLP TK+D ID S GQQA EKM +G+YLGE
Sbjct: 251 AHMNLPPDMPVAINCEYGAFDNEH-VVLPLTKYDHIIDRDSPRPGQQAFEKMTAGLYLGE 309
Query: 314 IARRVIVHL--SSINCLPAALQT-ALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
I R ++ L S + T L ++ F I D LQ T+ ++
Sbjct: 310 IFRLALIDLLDSRPGLIFQNQDTSKLRKPYLLDASFLAAIEEDPYENLQETQELFERELN 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ ++ +L +IR + L+ RAA+LSA A K + + DGSVF K P F+
Sbjct: 370 IK-PTLAELEMIRRLAELIGTRAARLSACGVAAI-CKKKNIESCHVGADGSVFTKYPHFK 427
Query: 431 RVLQDNINRILGP----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ IL + V + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAQALREILDWAPNEKDKVTIMAAEDGSGVGAALIAALTLKR 471
>ref|XP_380676.1| hypothetical protein FG00500.1 [Gibberella zeae PH-1]
Length = 572
Score = 549 bits (1415), Expect = e-154, Method: Composition-based stats.
Identities = 149/470 (31%), Positives = 233/470 (49%), Gaps = 18/470 (3%)
Query: 16 GNDGETVRAVKRDVAMA--ALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSY 73
G+ ++ V +D+A L N FT+ +++I + + E+ +GL ++ M P++
Sbjct: 90 GSQRGSMADVPKDLAEEINKLENLFTVQPSKLKEITNHFVSELAKGLSVEGGSIPMNPTW 149
Query: 74 VYKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFG 132
V TG + ALD+GGTN RV ++ E + D S +++P+ G + +L+
Sbjct: 150 VMSYPDGYETGTYLALDMGGTNLRVCQITLTDEKSEFDIIQSKYRMPEELKSGTSEELWE 209
Query: 133 FIASNVKKTMETRAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDV 191
+IA + + +ET + +PLGFTFS+P Q ++ G+L RWTKGF GV+G ++
Sbjct: 210 YIAECLYQFLETHHGDCTKLEKIPLGFTFSYPATQNYIDEGILQRWTKGFDIDGVEGQNI 269
Query: 192 IALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVT 251
+ + + A + + + A+ NDT GTLI+ + D +++G I GTG NA Y E ++
Sbjct: 270 VPMFEEALKTRGVPIKLAAIINDTTGTLIASAYTDTAMKIGCIFGTGCNAAYMEDCGSIP 329
Query: 252 KDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYL 311
K + IN E G FD++++ VLP T +D+ ID S GQQA EKMI+G+YL
Sbjct: 330 KIADLNLPADLPMAINCEWGAFDNEHK-VLPRTPYDVIIDKESPRPGQQAFEKMIAGLYL 388
Query: 312 GEIARRVIVHLSSIN---CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKV 368
GEI R ++V L L S ++ F I D L T K
Sbjct: 389 GEIFRLILVDLHDNKSIHIFENQDIALLRKPYSLDASFLSAIEEDPWENLSETSDLFSKK 448
Query: 369 CGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPS 428
+ E L +IR L+ RAA+LSA A K + + DGSVF K P
Sbjct: 449 LNLKCTQPE-LELIRRTAELIGTRAARLSACGVAAI-CKKKNYQSCHVGADGSVFNKYPH 506
Query: 429 FRRVLQDNINRILGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
F+ + IL E + + A+DGSG+GAA I+A+ +
Sbjct: 507 FKERGAKALRDILDWPEKTNKKEEDPIEVLTAEDGSGVGAALIAALTLKR 556
>gb|AAY83348.1| hexokinase [Hypocrea jecorina]
Length = 492
Score = 548 bits (1412), Expect = e-154, Method: Composition-based stats.
Identities = 152/471 (32%), Positives = 237/471 (50%), Gaps = 16/471 (3%)
Query: 13 SIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPS 72
+ L FT+ +++I + + E+ +GL ++ M P+
Sbjct: 9 PPSRKGSAADLPKDLLNEVRKLEEIFTVDTAKLKEITDHFVNELAKGLSVEGGSIPMNPT 68
Query: 73 YVYKADPKRATGVFYALDLGGTNFRVLRVACKE-GAVVDSSTSAFKIPKYALEGNATDLF 131
+V TG F ALD+GGTN RV + + + D S +++P+ G++ +L+
Sbjct: 69 WVMSYPDGHETGSFLALDMGGTNLRVCEITLTDRKSEFDIIQSKYRMPEELKTGSSEELW 128
Query: 132 GFIASNVKKTMETRAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGND 190
+IA + + +ET + +PLGFTFS+P Q ++ G+L RWTKGF GV+G +
Sbjct: 129 EYIADCLHQFIETHHGDCSKLEALPLGFTFSYPATQHYIDEGILQRWTKGFDIAGVEGKN 188
Query: 191 VIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAV 250
V+ + +AA + + + + AL NDT GTLI+ + DP+V++G I GTG NA Y E ++
Sbjct: 189 VVPMFEAAIAKRGVPIKLSALINDTTGTLIASAYTDPKVKIGCIFGTGCNAAYMEDCGSI 248
Query: 251 TKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMY 310
K + IN E G FD++++ VLP TK+D+ ID+ S GQQA EKMI+G+Y
Sbjct: 249 PKLAHMNLPPDCPMAINCEWGAFDNEHK-VLPRTKYDIAIDEDSPRPGQQAFEKMIAGLY 307
Query: 311 LGEIARRVIVHLSSINCLP---AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQK 367
LGEI R V+V L + + L + +S F I D LQ T T Q
Sbjct: 308 LGEIFRLVLVDLHDNKDIHIFENQDISLLRRPYTLDSSFLSGIEEDPFENLQETFDTFQS 367
Query: 368 VCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIP 427
+ + +L ++R + L+ RAA+LSA A K ++ + DGSVF K P
Sbjct: 368 KLNI-TPTGPELELVRRLSELIGTRAARLSACGVAAI-CKKKSFESCHVGADGSVFNKYP 425
Query: 428 SFRRVLQDNINRILGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
F+ + IL E V + A+DGSG+GAA I+A+ +
Sbjct: 426 HFKARGAKALREILDWPAKSNPKEEDPVEILAAEDGSGVGAALIAALTLKR 476
>ref|XP_001912895.1| unnamed protein product [Podospora anserina]
emb|CAP60377.1| unnamed protein product [Podospora anserina]
Length = 482
Score = 547 bits (1410), Expect = e-154, Method: Composition-based stats.
Identities = 152/467 (32%), Positives = 237/467 (50%), Gaps = 18/467 (3%)
Query: 19 GETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYK 76
+ V +D+ + L FT+ ++QI + + E+ +GL T+ M P++V
Sbjct: 3 SGSFVEVPKDLLKEIKRLEELFTVDTAKLKQITDHFVNELEKGLSKEGGTIPMNPTWVMS 62
Query: 77 ADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGFIA 135
TG + ALD+GGTN RV ++ ++ + D S +++P+ G A DL+ +IA
Sbjct: 63 FPTGYETGTYLALDMGGTNLRVCQITLTEQKSEFDIIQSKYRMPEELKTGVAEDLWEYIA 122
Query: 136 SNVKKTMETRAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIAL 194
+ + ++T + +PLGFTFS+P Q ++ G+L RWTKGF GV+G +V+ +
Sbjct: 123 ECLLQFIQTHHGDVAKLDKLPLGFTFSYPATQNYIDEGILQRWTKGFDIDGVEGRNVVPM 182
Query: 195 LQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDP 254
+ A + + + AL NDT GTLI+ + D ++++G I GTG NA Y E ++ K
Sbjct: 183 FEKALQERGVPIKLTALINDTTGTLIASAYTDTKMKIGCIFGTGCNAAYMEDCGSIPKLA 242
Query: 255 AVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEI 314
+ IN E G FD++ + VLP T +D ID S GQQA EKMI+G+YLGEI
Sbjct: 243 HLNLPPDTPMAINCEWGAFDNELK-VLPRTPYDESIDTDSPRPGQQAFEKMIAGLYLGEI 301
Query: 315 ARRVIVHL---SSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGV 371
R ++V L ++N L + +S F I D L TR Q G+
Sbjct: 302 FRLIMVDLHDNHNVNIFAGQDIGKLRRPYTLDSSFLSAIEDDPFENLSETRELFQNQLGI 361
Query: 372 DVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRR 431
D + +L +IR L+ RAA+LSA A K + + DGSVF K P F++
Sbjct: 362 D-PNPSELELIRRAAELIGTRAARLSACGVAAI-SKKKGYKECHVGADGSVFNKYPHFKK 419
Query: 432 VLQDNINRILGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ IL + + + A+DGSG+GAA I+A+ +
Sbjct: 420 RGAAALREILDWPAKADPNDDDPIEILAAEDGSGVGAALIAALTLER 466
>ref|XP_364444.1| hexokinase [Magnaporthe grisea 70-15]
gb|EDJ97892.1| hexokinase [Magnaporthe grisea 70-15]
Length = 477
Score = 546 bits (1407), Expect = e-153, Method: Composition-based stats.
Identities = 151/458 (32%), Positives = 229/458 (50%), Gaps = 16/458 (3%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGV 85
+ L FT+ ++QI + + E+ GL + M P++V TG
Sbjct: 7 DLVKEIKDLEEMFTVDTAKLKQITNHFVGELERGLSVEGGDIPMNPTWVMSFPDGYETGT 66
Query: 86 FYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMET 144
F ALD+GGTN RV + + + D S +++P+ G + +L+ +IA + + +ET
Sbjct: 67 FLALDMGGTNLRVCEITLTDQKSEFDIIQSKYRMPEELKTGQSDELWDYIADCLLQFIET 126
Query: 145 RAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS 203
+ +PLGFTFS+P Q V+ G+L RWTKGF GV+G +V +L A
Sbjct: 127 HHGDPKKIEKLPLGFTFSYPATQNYVDEGILQRWTKGFDIAGVEGKNVAPMLMKALSERG 186
Query: 204 LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSAL 263
+ V +VAL NDT GTLI+ + D ++++G I GTG NA Y E ++ K +
Sbjct: 187 VPVKLVALINDTTGTLIASAYTDTQMRIGCIFGTGCNAAYMEECGSIPKLAHMNLPPETP 246
Query: 264 TPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHL- 322
IN E G FD++++ VLP T +D+ ID+ S GQQA EKMI+G+YLGEI R ++V L
Sbjct: 247 MAINCEWGAFDNQHK-VLPRTPYDVKIDEDSPRPGQQAFEKMIAGLYLGEIFRLILVDLH 305
Query: 323 --SSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLR 380
+ + L + +S F I D L T Q + V + +L
Sbjct: 306 DNHEVRIFKNQDISKLRRAYTLDSSFLSAIEDDPWENLSETLDLFQDKLNL-VPNRNELE 364
Query: 381 IIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRI 440
+IR L+ RAA+LSA A K + + DGSVF K P+F++ + I
Sbjct: 365 LIRRTAELIGTRAARLSACGVAAI-CKKKNYRSCHVGADGSVFNKYPNFKQRGAQALREI 423
Query: 441 LGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
L E + + A+DGSG+GAA I+A+ +
Sbjct: 424 LDWPAKEDPKEEDPIEILAAEDGSGVGAALIAALTLKR 461
>ref|XP_001597079.1| hypothetical protein SS1G_01273 [Sclerotinia sclerotiorum 1980]
gb|EDN96347.1| hypothetical protein SS1G_01273 [Sclerotinia sclerotiorum 1980]
Length = 491
Score = 542 bits (1397), Expect = e-152, Method: Composition-based stats.
Identities = 147/468 (31%), Positives = 240/468 (51%), Gaps = 17/468 (3%)
Query: 17 NDGETVRAVKRD--VAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V ++ + L QFT+ + +++I + + E+ +GL ++ M P++
Sbjct: 11 SRKGSMAEVPKNFLEQIKKLEQQFTVDTKKLKEITEHFVSELTKGLTVEGGSIPMNPTWC 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
TG F ALD+GGTN RV + E + D S +++P+ G+A +L+ +
Sbjct: 71 MSFPDGYETGTFLALDMGGTNLRVCEIILTDEKSEFDIMQSKYRMPEELKTGDADELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ +E+ + + LGFTFS+P Q ++ G+L RWTKGF +GV+G +V+
Sbjct: 131 IADCLQQFIESHHQGEKLDKLSLGFTFSYPATQNYIDEGILQRWTKGFDIEGVEGENVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
+ +AA + + + + AL NDT GTLI+ + D +++G I GTG NA Y E ++ K
Sbjct: 191 MFEAALAKRGVPIKLTALINDTTGTLIASAYTDTSMKIGCIFGTGCNAAYMENCGSIPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
+ IN E G FD++++ VLP T +D+ ID S GQQA EKMI+G+YLGE
Sbjct: 251 AHMNLPPDTPMAINCEWGAFDNEHK-VLPRTPYDIIIDKDSPRPGQQAFEKMIAGLYLGE 309
Query: 314 IARRVIVHLSSINCLP---AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
+ R V+V L + L + +S F ++ D L T Q G
Sbjct: 310 LFRLVLVDLHDNKDIHIFEGQDIEKLRKAYTLDSSFLSLVEEDPFENLSETADLFQNKLG 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ V ++ +L +IR + L+ RAA+LSA A K + + DGSVF K P F+
Sbjct: 370 I-VTTVPELELIRRLAELIGTRAARLSACGVAAI-AKKKGYETCHVGADGSVFNKYPHFK 427
Query: 431 RVLQDNINRILGPECD--------VRAVLAKDGSGIGAAFISAMVVND 470
+ IL + + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAAALREILDWPAKKSPKEHDPIEILAAEDGSGVGAALIAALTLKR 475
>ref|XP_001247226.1| hexokinase [Coccidioides immitis RS]
gb|EAS35643.1| hexokinase [Coccidioides immitis RS]
Length = 490
Score = 542 bits (1397), Expect = e-152, Method: Composition-based stats.
Identities = 162/464 (34%), Positives = 241/464 (51%), Gaps = 13/464 (2%)
Query: 17 NDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ + +D+ + L FT+ +++I+ + + E+ +GL + + M ++V
Sbjct: 11 SRKGSMADMPKDLLEQVKELEELFTVDQARLKKIVDHFVKELEKGLSVQGGNIPMNVTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
G F ALD+GGTN RV + ++ D + S ++IP+ GNA DL+ +
Sbjct: 71 MGFPTGHEHGTFLALDMGGTNLRVCEIFLCEKKGEFDITQSKYRIPEELKSGNADDLWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA V++ +E E+ +PLGFTFS+P Q ++ GVL RWTKGF GV+G DV+
Sbjct: 131 IADCVQQFIEYHHEEENLPDLPLGFTFSYPATQEYIDHGVLQRWTKGFDIDGVEGEDVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
+L+AA + L + V AL NDT GTLI+ + DPE+++G I GTG NA Y E A ++ K
Sbjct: 191 MLEAALAKRGLPIKVAALINDTTGTLIASAYTDPEMRIGCIFGTGVNAAYMENAGSIPKI 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
IN E G FD++ R VLP T++D+ ID S GQQA EKM +G+YLGE
Sbjct: 251 AHYNLPPDMPIAINCEYGAFDNE-RVVLPLTQYDVVIDRDSPRPGQQAFEKMTAGLYLGE 309
Query: 314 IARRVIVHLS--SINCLPAALQ-TALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
I R V++ L N + ++L +S F I D L TR ++ G
Sbjct: 310 IFRLVLLDLIDNKGNLIFEGQDVSSLRKPYCLDSSFLAYIEEDPFENLSETRDLFERTLG 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ E L + R + LV RAA+LSA A K + + DGSVF K P F+
Sbjct: 370 IKATKPE-LELCRRLAELVGTRAARLSACGVAAI-CKKKNIKSCHVGADGSVFNKYPHFK 427
Query: 431 RVLQDNINRILGP----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ IL E V A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAKALREILDWADDEEDKVIICSAEDGSGVGAALIAALTLER 471
>ref|XP_001275241.1| hexokinase Kxk, putative [Aspergillus clavatus NRRL 1]
gb|EAW13815.1| hexokinase Kxk, putative [Aspergillus clavatus NRRL 1]
Length = 490
Score = 541 bits (1395), Expect = e-152, Method: Composition-based stats.
Identities = 151/464 (32%), Positives = 237/464 (51%), Gaps = 13/464 (2%)
Query: 17 NDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V +++ + + FT+ ++Q++ + + E+ +GL + M ++V
Sbjct: 11 SRKGSMADVPQNLLQQIKEFEDMFTVDRTKLKQVVDHFVKELEQGLTVEGGNIPMNVTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
G F ALD+GGTN RV + +E D S +++P+ G A +L+ +
Sbjct: 71 MGFPDGDEQGTFLALDMGGTNLRVCEITLTEEKGAFDICQSKYRMPEELKTGTAEELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ ++ ++ +PLGFTFS+P Q ++ GVL RWTKGF GV+G DV+
Sbjct: 131 IADCLQQFIDFHHEDEELSQLPLGFTFSYPATQDYIDHGVLQRWTKGFDIDGVEGQDVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
L+A + L + V AL NDT GTLI+ + DPE+++G I GTG NA Y + +V K
Sbjct: 191 PLEAILQKKGLPIKVAALINDTTGTLIASAYTDPEMKIGCIFGTGVNAAYMDNVGSVPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
+ IN E G FD+++ VLP TK+D ID S GQQA EKM +G+YLGE
Sbjct: 251 AHMNLPPDMPVAINCEYGAFDNEH-IVLPLTKYDHIIDRDSPRPGQQAFEKMTAGLYLGE 309
Query: 314 IARRVIVHL--SSINCLPAALQT-ALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
I R ++ L S + T L ++ F I D L+ T+ Q+
Sbjct: 310 IFRLALIDLLDSRPGLIFEGQDTSKLRKPYLLDASFLAAIEEDPYENLEETQELFQRELN 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ + +L +IR + L+ RAA+LSA A K + R + DGSVF K P+F+
Sbjct: 370 IK-PTQAELEMIRRLAELIGTRAARLSACGVAAI-CKKKNIERCHVGADGSVFTKYPNFK 427
Query: 431 RVLQDNINRILGP----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ IL V + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAQALREILDWAPNENDKVSILAAEDGSGVGAALIAALTLKR 471
>gb|ABY89285.1| putative hexokinase HXK1 [Gibberella moniliformis]
Length = 492
Score = 540 bits (1393), Expect = e-152, Method: Composition-based stats.
Identities = 145/469 (30%), Positives = 235/469 (50%), Gaps = 18/469 (3%)
Query: 17 NDGETVRAVKRDVA--MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V +D+A + L FT+ +++I + + E+ +GL ++ M P++V
Sbjct: 11 SRKGSMADVPKDLADEIHKLEKLFTVEPAKLKEITDHFVSELAKGLSVEGGSIPMNPTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
TG + ALD+GGTN RV ++ +E + D S +++P+ G + +L+ +
Sbjct: 71 MSYPDGYETGTYLALDMGGTNLRVCQITLTEEKSEFDILQSKYRMPEELKSGTSEELWEY 130
Query: 134 IASNVKKTMETRAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVI 192
IA + + +ET + +PLGFTFS+P Q ++ G+L RWTKGF GV+G +++
Sbjct: 131 IAECLYQFLETHHGDCSKLEKIPLGFTFSYPATQNYIDEGILQRWTKGFDIDGVEGKNIV 190
Query: 193 ALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTK 252
+ + A + + + A+ NDT GTLI+ + D +++G I GTG NA Y E ++ K
Sbjct: 191 PMFEEALKARGVPIKLAAIINDTTGTLIASAYTDTAMKIGCIFGTGCNAAYMEDCGSIPK 250
Query: 253 DPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLG 312
+ IN E G FD++++ VLP T +D+ ID S GQQA EKMI+G+YLG
Sbjct: 251 IADLNLPADLPMAINCEWGAFDNEHK-VLPRTAYDVTIDKESPRPGQQAFEKMIAGLYLG 309
Query: 313 EIARRVIVHLSSIN---CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVC 369
EI R ++V L + L S ++ F I D L T K
Sbjct: 310 EIFRLILVDLHDNKAIHIFENQDISLLRKPYSLDASFLSAIEEDPWENLTETYDLFVKKL 369
Query: 370 GVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSF 429
+ + +L ++R L+ RAA+LSA A K + + DGSVF K P F
Sbjct: 370 NLK-PTRPELELVRRTAELIGTRAARLSACGVAAI-CKKKGYESCHVGADGSVFNKYPYF 427
Query: 430 RRVLQDNINRILGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ + IL E + + A+DGSG+GAA I+A+ +
Sbjct: 428 KERGAQALREILDWPEKTDKKAEDPIEVLTAEDGSGVGAALIAALTLKR 476
>ref|XP_001386689.2| Hexokinase [Pichia stipitis CBS 6054]
gb|ABN68660.2| Hexokinase [Pichia stipitis CBS 6054]
Length = 482
Score = 540 bits (1393), Expect = e-152, Method: Composition-based stats.
Identities = 156/445 (35%), Positives = 232/445 (52%), Gaps = 10/445 (2%)
Query: 30 AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYAL 89
+ L + F +S E++R+I + + E+ +GL + + M+P +V + TG + A+
Sbjct: 26 ELEQLESVFNVSAETLRKITDHFVLELEKGLSKKGGNIPMIPGWVLDFPTGKETGDYLAI 85
Query: 90 DLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
DLGGTN RV+ V D++ S + +P + +L+ FIA +KK +E PE
Sbjct: 86 DLGGTNLRVVLVKLGGNRDFDTTQSKYPLPATMRTAKSEELWDFIAGCLKKFVEDEYPEG 145
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVV 209
+ +PLGFTFS+P Q+ +N G L RWTKGF GV+G DV+ +LQ A + ++ + VV
Sbjct: 146 VTEPLPLGFTFSYPASQSSINEGFLQRWTKGFDIDGVEGRDVVPMLQEAIKKENVPIEVV 205
Query: 210 ALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR---GSALTPI 266
AL NDT GTL++ + DPE ++G+I GTG N Y++ + K G +L I
Sbjct: 206 ALINDTTGTLVASAYTDPETKMGLIFGTGCNGAYYDVCGEIPKLEGQFHGDVAGESLMAI 265
Query: 267 NMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSIN 326
N E G FD++ VLP +KFD ID S GQQA EKMISG YLGE+ R ++ LS+
Sbjct: 266 NCEYGAFDNELA-VLPRSKFDHQIDAESPRPGQQAFEKMISGYYLGEVLRLALLDLSAKG 324
Query: 327 CLPAALQ-TALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDV 385
+ L ++ F I D L + Q+ G+ E +IR +
Sbjct: 325 IFFKDQDLSKLNQPFILDTSFPARIEEDPYENLSDVQDLFQQELGIQTTDAE-RSVIRRL 383
Query: 386 CRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGP-- 443
++ R+A+LS A K + A A DGSVF K P F+ + I
Sbjct: 384 AEVIGERSARLSVCGIAAI-CKKRGYKTAHAAADGSVFNKYPGFKERAAKGLRDIFQWET 442
Query: 444 -ECDVRAVLAKDGSGIGAAFISAMV 467
E + V A+DGSG+GAA I+A+
Sbjct: 443 KEDPIIIVPAEDGSGVGAAVIAALT 467
>ref|XP_001549109.1| hexokinase [Botryotinia fuckeliana B05.10]
gb|ABM30191.1| hexokinase [Botryotinia fuckeliana]
gb|EDN33783.1| hexokinase [Botryotinia fuckeliana B05.10]
Length = 491
Score = 540 bits (1392), Expect = e-151, Method: Composition-based stats.
Identities = 144/452 (31%), Positives = 231/452 (51%), Gaps = 15/452 (3%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALD 90
+ L QFT+ + +++I + + E+ +GL ++ M P++ TG F ALD
Sbjct: 27 IKKLEQQFTVDTQKLKEITEHFVSELTKGLTVEGGSIPMNPTWCMAFPDGYETGTFLALD 86
Query: 91 LGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
+GGTN RV + E + D S +++P+ G A +L+ +IA +++ +E+ +
Sbjct: 87 MGGTNLRVCEIILTDEKSEFDIIQSKYRMPEELKTGEADELWEYIADCLQQFIESHHHGE 146
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVV 209
T+ LGFTFS+P Q ++ G+L RWTKGF GV+G +++ + +AA + + + +
Sbjct: 147 DLGTLSLGFTFSYPATQNYIDEGILQRWTKGFDIAGVEGENIVPMFEAALAKRGVPIKLT 206
Query: 210 ALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINME 269
AL NDT GTLI+ + D +++G I GTG NA Y E ++ K + IN E
Sbjct: 207 ALINDTTGTLIASAYTDTAMKIGCIFGTGCNAAYMENCGSIPKLAHMNLPPDTPMAINCE 266
Query: 270 SGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP 329
G FD++++ VLP T +D+ ID S GQQA EKMI+G+YLGE+ R V+V L +
Sbjct: 267 WGAFDNEHK-VLPRTPYDIIIDKDSPRPGQQAFEKMIAGLYLGELFRLVLVDLHDNKDIH 325
Query: 330 ---AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVC 386
L + +S F ++ D L T Q + ++ +L +IR +
Sbjct: 326 MFEGQDIEKLRKAYTLDSSFLSLVEEDPWENLSETADLFQNKLSIRA-TVPELELIRRLA 384
Query: 387 RLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECD 446
L+ RAA+LSA A K + + DGSVF K P F+ + IL
Sbjct: 385 ELIGTRAARLSACGVAAI-AKKKNYETCHVGADGSVFNKYPHFKARGAAALREILDWPAK 443
Query: 447 --------VRAVLAKDGSGIGAAFISAMVVND 470
+ + A+DGSG+GAA I+A+ +
Sbjct: 444 KNAKEADPIEILAAEDGSGVGAALIAALTLKR 475
>ref|XP_001850122.1| hexokinase [Culex pipiens quinquefasciatus]
gb|EDS31457.1| hexokinase [Culex pipiens quinquefasciatus]
Length = 449
Score = 539 bits (1390), Expect = e-151, Method: Composition-based stats.
Identities = 149/445 (33%), Positives = 231/445 (51%), Gaps = 9/445 (2%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFY 87
+ + ++ + M +IM +L E+ GL + V+ +YV + G F
Sbjct: 7 IREQCQELILTDKQMEEIMRRVLKEINNGLHKETQPTADVKCFITYVQDLPNGKEKGKFL 66
Query: 88 ALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAP 147
ALDLGGTNFRVL + K+ + + + IP+ + G+ T LF IA + M+ A
Sbjct: 67 ALDLGGTNFRVLLIHLKDENDFEMLSKIYAIPQSIMLGSGTQLFDHIAECLANFMKEHAV 126
Query: 148 EDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKV 206
D +PLGFTFSFP+ Q + +G+L RWTKGF+ GV G DV+ LL+ A R +++
Sbjct: 127 YD--EKLPLGFTFSFPLTQLGLTKGMLARWTKGFNCSGVVGEDVVQLLKDAIARRGDVQI 184
Query: 207 NVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPI 266
+ A+ NDT GTL+S +K+ ++G+I+GTGSNACY E I
Sbjct: 185 EICAILNDTTGTLMSCAWKNHNCRIGLIVGTGSNACYVEKVENCEMFDGYKDPNKQHVLI 244
Query: 267 NMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSIN 326
N E G F T++D +ID S+NKG+Q EKMISGMY+GE+AR IV +
Sbjct: 245 NTEWGAFGDNGALDFVRTEYDREIDHFSINKGRQIQEKMISGMYMGELARLAIVKFTKAG 304
Query: 327 CLPAAL-QTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDV 385
L + L RG F +++ I +D+ + R + G++ + ED +R +
Sbjct: 305 LLFGGVGSDILFKRGQFFTKYVSEIESDKPGTYSYCRDVL-DELGLEHATDEDCANVRYI 363
Query: 386 CRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPEC 445
C V RAA L ++ A L+ + T+ +DGSV+ P F ++ I + + P+
Sbjct: 364 CECVSSRAAHLVSAGIAA-LINKMDEKSVTVGVDGSVYRFHPKFHDLMVQKIRQFVKPDI 422
Query: 446 DVRAVLAKDGSGIGAAFISAMVVND 470
+L++DGSG GAA ++A+ +
Sbjct: 423 SFDLMLSEDGSGRGAALVAAVACRE 447
>ref|NP_079406.3| hexokinase domain containing 1 [Homo sapiens]
sp|Q2TB90|HKDC1_HUMAN Putative hexokinase HKDC1 (Hexokinase domain-containing protein 1)
gb|AAI10505.1| Hexokinase domain containing 1 [Homo sapiens]
gb|AAI10506.2| Hexokinase domain containing 1 [Homo sapiens]
gb|EAW54318.1| hexokinase domain containing 1, isoform CRA_b [Homo sapiens]
Length = 917
Score = 539 bits (1389), Expect = e-151, Method: Composition-based stats.
Identities = 162/468 (34%), Positives = 250/468 (53%), Gaps = 27/468 (5%)
Query: 13 SIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRM 69
++ + + R +A+ F ++ E + + + E+ GL+ + +TVRM
Sbjct: 458 AVASRVQAQRKQIDRVLAL------FQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRM 511
Query: 70 LPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGA-VVDSSTSAFKIPKYALEGNAT 128
LP+YV G F ALDLGGTNFRVL V + G V F IP ++G
Sbjct: 512 LPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGE 571
Query: 129 DLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQG 188
+LF I + ++ + ++PLGFTFSFP Q +++G LI WTKGF +G
Sbjct: 572 ELFDHIVQCIADFLDYMGLK--GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEG 629
Query: 189 NDVIALLQAAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETA 247
DV+ +L+ A R + +++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E
Sbjct: 630 EDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDM 689
Query: 248 SAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMIS 307
+ G IN E G F T++D ++D+ SLN G+Q EKM S
Sbjct: 690 RNIEMVEG----GEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTS 745
Query: 308 GMYLGEIARRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQ 366
GMYLGEI R++++ L+ L + L RG FE++F I +DR+ LQ R +Q
Sbjct: 746 GMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQ-VRRILQ 804
Query: 367 KVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGS 421
+ G+D + ED ++++VC V RAAQL + A + K + R T+ +DG+
Sbjct: 805 Q-LGLD-STCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGT 862
Query: 422 VFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+++ P F R+LQ+ + L P CDV +L++DGSG GAA I+A+
Sbjct: 863 LYKLHPHFSRILQETVKE-LAPRCDVTFMLSEDGSGKGAALITAVAKR 909
Score = 450 bits (1159), Expect = e-125, Method: Composition-based stats.
Identities = 153/451 (33%), Positives = 238/451 (52%), Gaps = 22/451 (4%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGREST---VRMLPSYVYKADPKRATGVFY 87
+ +S +++ IM EM +GL + V+MLP++V G F
Sbjct: 22 VDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFL 81
Query: 88 ALDLGGTNFRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETR 145
+LDLGG+ FRVL+V E V + + P + GN T+LF ++A + M+T+
Sbjct: 82 SLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTK 141
Query: 146 APEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SL 204
+ ++ +PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A R +
Sbjct: 142 DLK--HKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDM 199
Query: 205 KVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALT 264
V+++AL NDTVGT+++ + DP +VGVIIGTG+NACY E S + R
Sbjct: 200 DVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR----M 255
Query: 265 PINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSS 324
IN E G F T+FD ++D SLN G+Q EKMISG+YLGE+ R +++ ++
Sbjct: 256 CINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAK 315
Query: 325 INCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIR 383
L +AL +G E+R + + GL TR + G++ S D ++
Sbjct: 316 AGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREILVD-LGLE-PSEADCIAVQ 372
Query: 384 DVCRLVRGRAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNIN 438
VC +V R+A L A+ A L K + R T+ +DG++++ P + + L +
Sbjct: 373 HVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVR 432
Query: 439 RILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+++ P CDVR +L++ GS GAA ++A+
Sbjct: 433 KLV-PSCDVRFLLSESGSTKGAAMVTAVASR 462
>dbj|BAF83713.1| unnamed protein product [Homo sapiens]
Length = 917
Score = 539 bits (1389), Expect = e-151, Method: Composition-based stats.
Identities = 162/468 (34%), Positives = 250/468 (53%), Gaps = 27/468 (5%)
Query: 13 SIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRM 69
++ + + R +A+ F ++ E + + + E+ GL+ + +TVRM
Sbjct: 458 AVASRVQAQRKQIDRVLAL------FQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRM 511
Query: 70 LPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGA-VVDSSTSAFKIPKYALEGNAT 128
LP+YV G F ALDLGGTNFRVL V + G V F IP ++G
Sbjct: 512 LPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGE 571
Query: 129 DLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQG 188
+LF I + ++ + ++PLGFTFSFP Q +++G LI WTKGF +G
Sbjct: 572 ELFDHIVQCIADFLDYMGLK--GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEG 629
Query: 189 NDVIALLQAAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETA 247
DV+ +L+ A R + +++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E
Sbjct: 630 EDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDM 689
Query: 248 SAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMIS 307
+ G IN E G F T++D ++D+ SLN G+Q EKM S
Sbjct: 690 RNIEMVEG----GEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTS 745
Query: 308 GMYLGEIARRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQ 366
GMYLGEI R++++ L+ L + L RG FE++F I +DR+ LQ R +Q
Sbjct: 746 GMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQ-VRRILQ 804
Query: 367 KVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGS 421
+ G+D + ED ++++VC V RAAQL + A + K + R T+ +DG+
Sbjct: 805 Q-LGLD-STCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGT 862
Query: 422 VFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+++ P F R+LQ+ + L P CDV +L++DGSG GAA I+A+
Sbjct: 863 LYKLHPHFSRILQETVKE-LAPRCDVTFMLSEDGSGKGAALITAVAKR 909
Score = 450 bits (1157), Expect = e-124, Method: Composition-based stats.
Identities = 153/451 (33%), Positives = 238/451 (52%), Gaps = 22/451 (4%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGREST---VRMLPSYVYKADPKRATGVFY 87
+ +S +++ IM EM +GL + V+MLP++V G F
Sbjct: 22 VDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFL 81
Query: 88 ALDLGGTNFRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETR 145
+LDLGG+ FRVL+V E V + + P + GN T+LF ++A + M+T+
Sbjct: 82 SLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNDIIRGNGTELFEYVADCLADFMKTK 141
Query: 146 APEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SL 204
+ ++ +PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A R +
Sbjct: 142 DLK--HKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDM 199
Query: 205 KVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALT 264
V+++AL NDTVGT+++ + DP +VGVIIGTG+NACY E S + R
Sbjct: 200 DVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR----M 255
Query: 265 PINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSS 324
IN E G F T+FD ++D SLN G+Q EKMISG+YLGE+ R +++ ++
Sbjct: 256 CINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAK 315
Query: 325 INCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIR 383
L +AL +G E+R + + GL TR + G++ S D ++
Sbjct: 316 AGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREILVD-LGLE-PSEADCIAVQ 372
Query: 384 DVCRLVRGRAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNIN 438
VC +V R+A L A+ A L K + R T+ +DG++++ P + + L +
Sbjct: 373 HVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVR 432
Query: 439 RILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+++ P CDVR +L++ GS GAA ++A+
Sbjct: 433 KLV-PSCDVRFLLSESGSTKGAAMVTAVASR 462
>gb|AAH12337.1| HKDC1 protein [Homo sapiens]
Length = 677
Score = 538 bits (1386), Expect = e-151, Method: Composition-based stats.
Identities = 162/468 (34%), Positives = 250/468 (53%), Gaps = 27/468 (5%)
Query: 13 SIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRM 69
++ + + R +A+ F ++ E + + + E+ GL+ + +TVRM
Sbjct: 218 AVASRVQAQRKQIDRVLAL------FQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRM 271
Query: 70 LPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGA-VVDSSTSAFKIPKYALEGNAT 128
LP+YV G F ALDLGGTNFRVL V + G V F IP ++G
Sbjct: 272 LPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGE 331
Query: 129 DLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQG 188
+LF I + ++ + ++PLGFTFSFP Q +++G LI WTKGF +G
Sbjct: 332 ELFDHIVQCIADFLDYMGLK--GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEG 389
Query: 189 NDVIALLQAAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETA 247
DV+ +L+ A R + +++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E
Sbjct: 390 EDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDM 449
Query: 248 SAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMIS 307
+ G IN E G F T++D ++D+ SLN G+Q EKM S
Sbjct: 450 RNIEMVEG----GEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTS 505
Query: 308 GMYLGEIARRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQ 366
GMYLGEI R++++ L+ L + L RG FE++F I +DR+ LQ R +Q
Sbjct: 506 GMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQ-VRRILQ 564
Query: 367 KVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGS 421
+ G+D + ED ++++VC V RAAQL + A + K + R T+ +DG+
Sbjct: 565 Q-LGLD-STCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGT 622
Query: 422 VFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+++ P F R+LQ+ + L P CDV +L++DGSG GAA I+A+
Sbjct: 623 LYKLHPHFSRILQETVKE-LAPRCDVTFMLSEDGSGKGAALITAVAKR 669
Score = 206 bits (524), Expect = 4e-51, Method: Composition-based stats.
Identities = 68/230 (29%), Positives = 112/230 (48%), Gaps = 14/230 (6%)
Query: 246 TASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKM 305
S + R IN E G F T+FD ++D SLN G+Q EKM
Sbjct: 1 DMSNIDLVEGDEGR----MCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKM 56
Query: 306 ISGMYLGEIARRVIVHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRST 364
ISG+YLGE+ R +++ ++ L +AL +G E+R + + GL TR
Sbjct: 57 ISGLYLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREI 115
Query: 365 IQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLV-----KTQTQGRATIAID 419
+ G++ S D ++ VC +V R+A L A+ A L K + R T+ +D
Sbjct: 116 LVD-LGLE-PSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMD 173
Query: 420 GSVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
G++++ P + + L + +++ P CDVR +L++ GS GAA ++A+
Sbjct: 174 GTLYKIHPQYPKRLHKVVRKLV-PSCDVRFLLSESGSTKGAAMVTAVASR 222
>ref|XP_001215959.1| hexokinase [Aspergillus terreus NIH2624]
gb|EAU33325.1| hexokinase [Aspergillus terreus NIH2624]
Length = 490
Score = 538 bits (1386), Expect = e-151, Method: Composition-based stats.
Identities = 147/448 (32%), Positives = 221/448 (49%), Gaps = 11/448 (2%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALD 90
+ + FT+ ++Q++ + + E+ +GL + M ++V G F ALD
Sbjct: 27 IKEFEDIFTVDTAKLKQVVAHFVKELEKGLTVEGGNIPMNVTWVMGFPDGNEQGTFLALD 86
Query: 91 LGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
+GGTN RV + +E D + S +++P+ G A +L+ +IA +++ + +
Sbjct: 87 MGGTNLRVCEITLTEEKGAFDITQSKYRMPEELKTGTAEELWEYIADCLEQFINAHHENE 146
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVV 209
+PLGFTFS+P Q ++ G+L RWTKGF GV+G DV+ L+ + L + V
Sbjct: 147 NLDKLPLGFTFSYPATQEYIDHGILQRWTKGFDIDGVEGQDVVPPLEEILKKRGLPIKVA 206
Query: 210 ALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINME 269
AL NDT GTLI+ + DP +++G I GTG NA Y E +V K + IN E
Sbjct: 207 ALINDTTGTLIASAYTDPAIKIGCIFGTGVNAAYMEDVGSVPKLAYMNLPPDMPVAINCE 266
Query: 270 SGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSIN--- 326
G FD+++ VLP TK+D ID S GQQA EKM +G+YLGEI R ++ L
Sbjct: 267 YGAFDNEH-VVLPLTKYDHIIDRDSPRPGQQAFEKMTAGLYLGEIFRLALLDLLESRPGL 325
Query: 327 CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVC 386
+ L +S F I D LQ T +++ + E L +IR +
Sbjct: 326 IFNGQDTSLLRKPYLLDSSFLAAIEEDPYENLQETSELLERKLNIKATEAE-LEMIRRLA 384
Query: 387 RLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPE-- 444
L+ RAA+LSA A K + DGSVF K P F+ + IL
Sbjct: 385 ELIGTRAARLSACGVAAICTKK-NIKSCHVGADGSVFTKYPHFKARGAQALREILDWAPN 443
Query: 445 --CDVRAVLAKDGSGIGAAFISAMVVND 470
V + A+DGSG+GAA I+A+ +
Sbjct: 444 EPDRVEILAAEDGSGVGAALIAALTLKR 471
>ref|XP_001660030.1| hexokinase [Aedes aegypti]
gb|EAT38748.1| hexokinase [Aedes aegypti]
Length = 461
Score = 537 bits (1385), Expect = e-151, Method: Composition-based stats.
Identities = 147/448 (32%), Positives = 231/448 (51%), Gaps = 9/448 (2%)
Query: 28 DVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEG---RESTVRMLPSYVYKADPKRATG 84
+ + +S + + +IM LL E+ GL E+ ++ +YV + G
Sbjct: 16 SKEIREQCQELILSDKQIEEIMRRLLKEINRGLGKATQPEADIKCFITYVQDLPNGKEKG 75
Query: 85 VFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMET 144
F ALDLGGTNFRVL + K+ + + + IP+ + G+ T LF IA + M+
Sbjct: 76 KFLALDLGGTNFRVLLIHLKDENDFEMLSKIYAIPQSIMLGSGTQLFDHIAECLANFMKE 135
Query: 145 RAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS- 203
+ +PLGFTFSFP+ Q + +G+L RWTKGF+ GV G DV+ LL+ A R
Sbjct: 136 HSV--YEEKLPLGFTFSFPLTQLGLTKGILARWTKGFNCSGVVGEDVVQLLKDAIARRGD 193
Query: 204 LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSAL 263
+++ + A+ NDT GTL+S +K+ ++G+I+GTGSNACY E
Sbjct: 194 VQIEICAILNDTTGTLMSCAWKNHNCRIGLIVGTGSNACYVEKVENCEMFDGPKDPKKEH 253
Query: 264 TPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLS 323
IN E G F T++D +ID S+N G+Q EKMISGMY+GE+AR IV +
Sbjct: 254 VLINTEWGAFGDNGALDFVRTEYDREIDHFSINPGRQIQEKMISGMYMGELARLAIVKFT 313
Query: 324 SINCLPAAL-QTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRII 382
L + L RG F +++ I +D+ + R + G++ + ED +
Sbjct: 314 RAGLLFGGVGSDILFKRGQFFTKYVSEIESDKPGTYMYCRDVL-DELGLEHATDEDCANV 372
Query: 383 RDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILG 442
R +C V RAA L ++ A L+ + T+ +DGSV+ P F +++ I + +
Sbjct: 373 RYICECVSSRAAHLVSAGIAA-LINKMDEKSVTVGVDGSVYRFHPKFHDLMKAKIRQFVK 431
Query: 443 PECDVRAVLAKDGSGIGAAFISAMVVND 470
P+ +L++DGSG GAA ++A+ +
Sbjct: 432 PDISFDLMLSEDGSGRGAALVAAVACRE 459
>ref|XP_001660031.1| hexokinase [Aedes aegypti]
gb|EAT38749.1| hexokinase [Aedes aegypti]
Length = 453
Score = 537 bits (1385), Expect = e-151, Method: Composition-based stats.
Identities = 147/445 (33%), Positives = 231/445 (51%), Gaps = 9/445 (2%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGLEG---RESTVRMLPSYVYKADPKRATGVFY 87
+ + +S + + +IM LL E+ GL E+ ++ +YV + G F
Sbjct: 11 IREQCQELILSDKQIEEIMRRLLKEINRGLGKATQPEADIKCFITYVQDLPNGKEKGKFL 70
Query: 88 ALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAP 147
ALDLGGTNFRVL + K+ + + + IP+ + G+ T LF IA + M+ +
Sbjct: 71 ALDLGGTNFRVLLIHLKDENDFEMLSKIYAIPQSIMLGSGTQLFDHIAECLANFMKEHSV 130
Query: 148 EDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKV 206
+PLGFTFSFP+ Q + +G+L RWTKGF+ GV G DV+ LL+ A R +++
Sbjct: 131 --YEEKLPLGFTFSFPLTQLGLTKGILARWTKGFNCSGVVGEDVVQLLKDAIARRGDVQI 188
Query: 207 NVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPI 266
+ A+ NDT GTL+S +K+ ++G+I+GTGSNACY E I
Sbjct: 189 EICAILNDTTGTLMSCAWKNHNCRIGLIVGTGSNACYVEKVENCEMFDGPKDPKKEHVLI 248
Query: 267 NMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSIN 326
N E G F T++D +ID S+N G+Q EKMISGMY+GE+AR IV +
Sbjct: 249 NTEWGAFGDNGALDFVRTEYDREIDHFSINPGRQIQEKMISGMYMGELARLAIVKFTRAG 308
Query: 327 CLPAAL-QTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDV 385
L + L RG F +++ I +D+ + R + G++ + ED +R +
Sbjct: 309 LLFGGVGSDILFKRGQFFTKYVSEIESDKPGTYMYCRDVL-DELGLEHATDEDCANVRYI 367
Query: 386 CRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPEC 445
C V RAA L ++ A L+ + T+ +DGSV+ P F +++ I + + P+
Sbjct: 368 CECVSSRAAHLVSAGIAA-LINKMDEKSVTVGVDGSVYRFHPKFHDLMKAKIRQFVKPDI 426
Query: 446 DVRAVLAKDGSGIGAAFISAMVVND 470
+L++DGSG GAA ++A+ +
Sbjct: 427 SFDLMLSEDGSGRGAALVAAVACRE 451
>ref|XP_001502742.1| PREDICTED: similar to hexokinase domain containing 1 [Equus
caballus]
Length = 916
Score = 537 bits (1385), Expect = e-151, Method: Composition-based stats.
Identities = 159/458 (34%), Positives = 244/458 (53%), Gaps = 21/458 (4%)
Query: 23 RAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADP 79
R + + + F ++ E + + + E+ GL+ +TV+MLP+YV
Sbjct: 462 RVQAQRKQIDKVLALFRLTQEQLVGVQDKMRAELEYGLKRDTHSLATVKMLPTYVCGMPD 521
Query: 80 KRATGVFYALDLGGTNFRVLRVACKEGA-VVDSSTSAFKIPKYALEGNATDLFGFIASNV 138
G F ALDLGGTNFRVL V + G V F IP ++G +LF I +
Sbjct: 522 GTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCI 581
Query: 139 KKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAA 198
++ + +PLGFTFSFP Q +++G LI WTKGF +G DV+ +L+ A
Sbjct: 582 ADFLDYMGLK--GAQLPLGFTFSFPCRQASIDKGTLIGWTKGFKATDCEGEDVVDMLREA 639
Query: 199 FGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVA 257
R + +++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E +
Sbjct: 640 IKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNLCYMEEMRNIELVEGDE 699
Query: 258 ARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARR 317
+ IN E G F T++D ++D+ SLN G+Q EKM SGMYLGEI R+
Sbjct: 700 GK----MCINTEWGGFGDNGCIDDIRTQYDKEVDEGSLNPGKQRYEKMTSGMYLGEIVRQ 755
Query: 318 VIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSI 376
+++ L+ L + L RG FE++F I +DR+ LQ R +Q+ G+D +
Sbjct: 756 ILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQ-VRRILQQ-LGLD-STC 812
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
ED ++++VC V RAAQL + A + K + R T+ +DG++++ P F R
Sbjct: 813 EDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLERLRITVGVDGTLYKLHPHFSR 872
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+LQ+ + L P CDV +L++DGSG GAA I+A+
Sbjct: 873 ILQETVKE-LAPRCDVTFMLSEDGSGKGAALITAVAKR 909
Score = 450 bits (1157), Expect = e-124, Method: Composition-based stats.
Identities = 153/451 (33%), Positives = 236/451 (52%), Gaps = 22/451 (4%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKRATGVFY 87
+ +S E++ IM EM +GL ++V+MLP++V G F
Sbjct: 22 VDRFLYHMRLSDETLLDIMARFQAEMQKGLGKDTNPTASVKMLPTFVRAIPDGSENGEFL 81
Query: 88 ALDLGGTNFRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETR 145
+LDLGG+ FRVL+V E V + + P + GN +LF ++A + M T+
Sbjct: 82 SLDLGGSKFRVLKVQVSEEGKRNVQMESQFYPTPNEIIRGNGIELFEYVADCLADFMNTK 141
Query: 146 APEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SL 204
+ ++ +PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A R +
Sbjct: 142 GLK--HKRLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSCLTRAMKRHKDI 199
Query: 205 KVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALT 264
V+ +AL NDTVGT+++ + DP +VGVIIGTG+NACY E S + R
Sbjct: 200 NVDTLALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR----M 255
Query: 265 PINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSS 324
IN E G F T+FD ++D SLN G+Q EKMISG+YLGE+ R +++ ++
Sbjct: 256 CINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAK 315
Query: 325 INCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIR 383
L +AL +G E+R + + GL TR + G++ S D ++
Sbjct: 316 AGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREILTD-LGLE-PSEADCIAVQ 372
Query: 384 DVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNIN 438
VC +V R+A L A+ A L + + R T+ +DG++++ P + + L +
Sbjct: 373 HVCTIVSFRSANLCAAALAAILTRLRENKKLVRLRTTVGMDGTLYKIHPQYPKRLHKVVR 432
Query: 439 RILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
R++ P CDVR +L++ GS GAA ++A+
Sbjct: 433 RLV-PNCDVRFLLSESGSAKGAAMVTAVASR 462
>ref|XP_001819202.1| hypothetical protein [Aspergillus oryzae RIB40]
dbj|BAB12228.1| hexokinase [Aspergillus oryzae]
dbj|BAE57200.1| unnamed protein product [Aspergillus oryzae]
Length = 490
Score = 537 bits (1385), Expect = e-151, Method: Composition-based stats.
Identities = 149/464 (32%), Positives = 236/464 (50%), Gaps = 13/464 (2%)
Query: 17 NDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ + +++ + + FT+ ++QI + + E+ +GL + M ++V
Sbjct: 11 SRKGSMHELPQNLLEQIKQFEDIFTVDGAKLKQIADHFVKELEKGLSVEGGNIPMNVTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
G F ALD+GGTN RV + +E D + S +++P+ G A +L+ +
Sbjct: 71 MGFPDGDEQGTFLALDMGGTNLRVCEITLTEEKGAFDITQSKYRMPEELKTGTAEELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ +E+ + +PLGFTFS+P Q ++ GVL RWTKGF GV+G DV+
Sbjct: 131 IADCLQQFIESHHENEKLSKLPLGFTFSYPATQEYIDHGVLQRWTKGFDIDGVEGQDVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
L+A + L + V AL NDT GTLI+ + D ++++G I GTG NA Y E +V K
Sbjct: 191 PLEAILKKRGLPIKVAALINDTTGTLIASSYTDSDMKIGCIFGTGVNAAYMEHCGSVPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
IN E G FD+++ VLP TK+D+ ID S GQQA EKM +G+YLGE
Sbjct: 251 AHKNLPPDMPVAINCEYGAFDNEH-VVLPLTKYDIIIDRDSPRPGQQAFEKMTAGLYLGE 309
Query: 314 IARRVIVHLSSI--NCLPAALQTA-LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
I R ++ L + T+ L ++ F I D LQ T+ +++
Sbjct: 310 IFRLALLDLLETRPGLIFQGQDTSQLRKPYLLDASFLAAIEDDPYENLQETQELMERKLN 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ ++L +IR + L+ RAA+LSA A K + + DGSVF K P F+
Sbjct: 370 IKATQ-QELEMIRRLAELIGTRAARLSACGVAAI-CKKKNIESCHVGADGSVFTKYPHFK 427
Query: 431 RVLQDNINRILGP----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ IL + V + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAQALREILDWAPNEKDKVVIMAAEDGSGVGAALIAALTLKR 471
>gb|AAG28789.1|AF309088_1 hexokinase [Tuber borchii]
Length = 497
Score = 537 bits (1384), Expect = e-151, Method: Composition-based stats.
Identities = 154/468 (32%), Positives = 240/468 (51%), Gaps = 17/468 (3%)
Query: 17 NDGETVRAVKRDVA--MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V D+ + L FT+ + ++++ E+V+GL T+ M P++V
Sbjct: 11 SRKGSMHDVPNDLMKHIHDLEKMFTIDTTKLHEVVSVFQEELVKGLSVTGGTIPMNPTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVACKEG-AVVDSSTSAFKIPKYALEGNATDLFGF 133
TG + ALD+GGTN RV V E D S +++P+ G LF +
Sbjct: 71 IGYPTGDETGTYLALDMGGTNLRVCEVELPEEQGQYDIYQSKYRLPEEIKSGTGEQLFDY 130
Query: 134 IASNVKKTM-ETRAPEDLN--RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGND 190
IA VK+ + +D+ + + LGFTFS+P EQ ++ G+L RWTKGF +GV+G+D
Sbjct: 131 IAECVKQFLIANHEGQDIKDLKELHLGFTFSYPCEQNAIDHGILQRWTKGFDIEGVEGHD 190
Query: 191 VIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAV 250
V+ + + A R + + + AL NDT GTLI+ + D ++G I GTG NA Y ET +
Sbjct: 191 VVPMFEEALERKGVPIKITALVNDTTGTLIASAYTDNTTRIGCIFGTGCNAAYMETIGCI 250
Query: 251 TKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMY 310
K + S IN E G FD+++R VLP T +D ID+ S GQQ EKM++G+Y
Sbjct: 251 PKLAHMNLDPSLEIAINCEWGAFDNEHR-VLPRTVYDKHIDENSPRPGQQTFEKMVAGLY 309
Query: 311 LGEIARRVIVHLSSI---NCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQK 367
LGEI R V+V L S + + L S ++ F I +D L T + +K
Sbjct: 310 LGEIFRLVLVDLYSNPDVSIFEKQDISTLQAEYSLDASFLAEIESDPWENLMETHALFEK 369
Query: 368 VCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIP 427
+ V + + ++IR + L+ RAA+L A A K + + DGSVF K P
Sbjct: 370 KLKI-VTTEPERKLIRRLAELIGTRAARLGACGVAAI-CKMKNIESCHVGADGSVFNKYP 427
Query: 428 SFRRVLQDNINRILGP-----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+F+ + I G + ++ V ++DGSG+GAA I+A+ +
Sbjct: 428 NFQERGAKALREIFGWGRTIRKDPIQIVPSEDGSGVGAALIAALTMKR 475
>emb|CAH71500.1| hexokinase domain containing 1 [Homo sapiens]
Length = 917
Score = 537 bits (1384), Expect = e-151, Method: Composition-based stats.
Identities = 162/468 (34%), Positives = 250/468 (53%), Gaps = 27/468 (5%)
Query: 13 SIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRM 69
++ + + R +A+ F ++ E + + + E+ GL+ + +TVRM
Sbjct: 458 AVASRVQAQRKQIDRVLAL------FQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRM 511
Query: 70 LPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEG-AVVDSSTSAFKIPKYALEGNAT 128
LP+YV G F ALDLGGTNFRVL V + G V F IP ++G
Sbjct: 512 LPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGE 571
Query: 129 DLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQG 188
+LF I + ++ + ++PLGFTFSFP Q +++G LI WTKGF +G
Sbjct: 572 ELFDHIVQCIADFLDYMGLK--GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEG 629
Query: 189 NDVIALLQAAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETA 247
DV+ +L+ A R + +++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E
Sbjct: 630 EDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDM 689
Query: 248 SAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMIS 307
+ G IN E G F T++D ++D+ SLN G+Q EKM S
Sbjct: 690 RNIEMVEG----GEGKMCINTEWGGFGDNGCIDDIWTRYDTEVDEGSLNPGKQRYEKMTS 745
Query: 308 GMYLGEIARRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQ 366
GMYLGEI R++++ L+ L + L RG FE++F I +DR+ LQ R +Q
Sbjct: 746 GMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQ-VRRILQ 804
Query: 367 KVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGS 421
+ G+D + ED ++++VC V RAAQL + A + K + R T+ +DG+
Sbjct: 805 Q-LGLD-STCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGT 862
Query: 422 VFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+++ P F R+LQ+ + L P CDV +L++DGSG GAA I+A+
Sbjct: 863 LYKLHPHFSRILQETVKE-LAPRCDVTFMLSEDGSGKGAALITAVAKR 909
Score = 451 bits (1160), Expect = e-125, Method: Composition-based stats.
Identities = 153/451 (33%), Positives = 238/451 (52%), Gaps = 22/451 (4%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGREST---VRMLPSYVYKADPKRATGVFY 87
+ +S +++ IM EM +GL + V+MLP++V G F
Sbjct: 22 VDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFL 81
Query: 88 ALDLGGTNFRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETR 145
+LDLGG+ FRVL+V E V + + P + GN T+LF ++A + M+T+
Sbjct: 82 SLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTK 141
Query: 146 APEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SL 204
+ ++ +PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A R +
Sbjct: 142 DLK--HKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDM 199
Query: 205 KVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALT 264
V+++AL NDTVGT+++ + DP +VGVIIGTG+NACY E S + R
Sbjct: 200 DVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR----M 255
Query: 265 PINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSS 324
IN E G F T+FD ++D SLN G+Q EKMISG+YLGE+ R +++ ++
Sbjct: 256 CINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAK 315
Query: 325 INCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIR 383
L +AL +G E+R + + GL TR + G++ S D ++
Sbjct: 316 AGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREILVD-LGLE-PSEADCIAVQ 372
Query: 384 DVCRLVRGRAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNIN 438
VC +V R+A L A+ A L K + R T+ +DG++++ P + + L +
Sbjct: 373 HVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVR 432
Query: 439 RILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+++ P CDVR +L++ GS GAA ++A+
Sbjct: 433 KLV-PSCDVRFLLSESGSTKGAAMVTAVASR 462
>ref|XP_001110556.1| PREDICTED: similar to hexokinase domain containing 1 [Macaca
mulatta]
Length = 917
Score = 537 bits (1383), Expect = e-150, Method: Composition-based stats.
Identities = 160/458 (34%), Positives = 247/458 (53%), Gaps = 21/458 (4%)
Query: 23 RAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADP 79
R + + + F ++ E + + + E+ GL+ + +TVRMLP+YV
Sbjct: 462 RVQAQRKQIDKVLALFRLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPD 521
Query: 80 KRATGVFYALDLGGTNFRVLRVACKEG-AVVDSSTSAFKIPKYALEGNATDLFGFIASNV 138
G F ALDLGGTNFRVL V + G V F IP ++G +LF I +
Sbjct: 522 GTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLGIMQGTGEELFDHIVQCI 581
Query: 139 KKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAA 198
++ + ++PLGFTFSFP Q +++G LI WTKGF +G DV+ +L+ A
Sbjct: 582 ADFLDYMGLK--GASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREA 639
Query: 199 FGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVA 257
R + +++VA+ NDTVGT+++ ++DP ++G+I GTGSN CY E +
Sbjct: 640 IKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGDE 699
Query: 258 ARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARR 317
+ IN E G F T++D ++D+ SLN G+Q EKM SGMYLGEI R+
Sbjct: 700 GK----MCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQ 755
Query: 318 VIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSI 376
+++ L+ L + L RG FE++F I +DR+ LQ R+ +Q+ G+D +
Sbjct: 756 ILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQ-VRTILQQ-LGLD-STC 812
Query: 377 EDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRR 431
ED ++++VC V RAAQL + A + K + R T+ +DG++++ P F R
Sbjct: 813 EDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSR 872
Query: 432 VLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+LQ+ + L P CDV +L++DGSG GAA I+A+
Sbjct: 873 ILQETVKE-LAPRCDVTFMLSEDGSGKGAALITAVAKR 909
Score = 451 bits (1161), Expect = e-125, Method: Composition-based stats.
Identities = 152/451 (33%), Positives = 238/451 (52%), Gaps = 22/451 (4%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGREST---VRMLPSYVYKADPKRATGVFY 87
+ +S +++ IM EM +GL + V+MLP++V G F
Sbjct: 22 VDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFL 81
Query: 88 ALDLGGTNFRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETR 145
+LDLGG+ FRVL+V E V + + P + GN T+LF ++A + M+T+
Sbjct: 82 SLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTK 141
Query: 146 APEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SL 204
+ ++ +PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A R +
Sbjct: 142 DLK--HKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDM 199
Query: 205 KVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALT 264
V+++A+ NDTVGT+++ + DP +VGVIIGTG+NACY E S + R
Sbjct: 200 DVDILAVVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR----M 255
Query: 265 PINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSS 324
IN E G F T+FD ++D SLN G+Q EKMISG+YLGE+ R +++ ++
Sbjct: 256 CINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQMFEKMISGLYLGELVRLILLKMAK 315
Query: 325 INCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIR 383
L +AL +G E+R + + GL TR + G++ S D ++
Sbjct: 316 AGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREILVD-LGLE-PSEADCIAVQ 372
Query: 384 DVCRLVRGRAAQLSASFCCAPLV-----KTQTQGRATIAIDGSVFEKIPSFRRVLQDNIN 438
VC +V R+A L A+ A L K + R T+ +DG++++ P + + L +
Sbjct: 373 HVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGVDGTLYKIHPQYPKRLHKVVR 432
Query: 439 RILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+++ P CDVR +L++ GS GAA ++A+
Sbjct: 433 KLV-PSCDVRFLLSESGSTKGAAMVTAVASR 462
>ref|XP_717405.1| hexokinase II [Candida albicans SC5314]
gb|EAK98436.1| likely hexokinase II [Candida albicans SC5314]
Length = 484
Score = 536 bits (1381), Expect = e-150, Method: Composition-based stats.
Identities = 148/447 (33%), Positives = 236/447 (52%), Gaps = 12/447 (2%)
Query: 30 AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYAL 89
A+ + QFT+S + +R I+ + + E+ GL + M+P +V + TG + A+
Sbjct: 26 ALKPIQEQFTISADKLRAIVKHFISELDRGLSKAGGNIPMIPGWVMDFPTGKETGSYLAI 85
Query: 90 DLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPED 149
DLGGTN RV+ V D++ S F +P + + +L+ FIA +K+ ++ P+
Sbjct: 86 DLGGTNLRVVLVKLGGNRDFDTTQSKFALPAHMRTATSDELWDFIAKCLKEFVDEIYPDG 145
Query: 150 LNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVV 209
+ +PLGFTFS+P Q ++N G+L RWTKG+S G++G DV+ +LQ A +V + ++VV
Sbjct: 146 CSEPLPLGFTFSYPASQNRINEGILQRWTKGWSIDGIEGKDVVPMLQKAIKKVGVPIDVV 205
Query: 210 ALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAA---RGSALTPI 266
AL NDT GTL++ + DPE ++G+I GTG N YF+ + K + I
Sbjct: 206 ALINDTTGTLVASMYTDPEAKMGLIFGTGVNGAYFDVVKDIPKLEGKCPSDIPPESPMAI 265
Query: 267 NMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSIN 326
N E G+FD++ +++LP TK+D+ ID+ S GQQ EKMISG YLGE+ R +++ +
Sbjct: 266 NCEYGSFDNE-KYILPRTKYDVQIDEESPRPGQQTFEKMISGYYLGEVLRLILLEFAEEK 324
Query: 327 --CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRD 384
L ++ + I D L ++ G++ E +IIR
Sbjct: 325 KLIFKGQNLDKLKVPYVMDASYPSKIEEDPFENLSDVADLFREKLGIETTEPE-RKIIRC 383
Query: 385 VCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPE 444
+ L+ R+A+ S A + + A A DGSV+ K P F+ + I
Sbjct: 384 LAELIGERSARFSVCGIAAI-CQKRGYKTAHCAADGSVYNKYPGFKERTAQALRDIYEWP 442
Query: 445 CDVR----AVLAKDGSGIGAAFISAMV 467
DV+ V A+DGSG+GAA I+A+
Sbjct: 443 ADVKDPIIIVPAEDGSGVGAAVIAALT 469
>ref|NP_524848.1| Hexokinase A CG3001-PA, isoform A [Drosophila melanogaster]
gb|AAF46507.1| CG3001-PA, isoform A [Drosophila melanogaster]
gb|AAL39536.1| LD09907p [Drosophila melanogaster]
Length = 541
Score = 535 bits (1380), Expect = e-150, Method: Composition-based stats.
Identities = 148/456 (32%), Positives = 233/456 (51%), Gaps = 10/456 (2%)
Query: 20 ETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYK 76
+ A ++ + L Q ++ E ++++ +L+E+ GL + V+ +YV
Sbjct: 84 ALLSAAEKSKMVHELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKANVKCFVTYVQD 143
Query: 77 ADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIAS 136
G F ALDLGGTNFRVL + +E + + IP++ + G+ T LF IA
Sbjct: 144 LPNGNERGKFLALDLGGTNFRVLLIHLQENNDFQMESRIYAIPQHIMIGSGTQLFDHIAE 203
Query: 137 NVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQ 196
+ M +PLGFTFSFP+ Q + +G+L WTKGF+ GV DV+ LL+
Sbjct: 204 CLSNFMAEHNV--YKERLPLGFTFSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLK 261
Query: 197 AAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
A R ++++V A+ NDT GTL+S +K+ ++G+I+GTG+NACY E A
Sbjct: 262 DAIARRGDVQIDVCAILNDTTGTLMSCAWKNHNCKIGLIVGTGANACYMERVEEAELFAA 321
Query: 256 VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIA 315
R IN E G F T+FD DID S+N G+Q EKMISGMY+GE+
Sbjct: 322 EDPR-KKHVLINTEWGAFGDNGALDFVRTEFDRDIDVHSINPGKQTFEKMISGMYMGELV 380
Query: 316 RRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQ 374
R V+V ++ L L RG F +++ I AD R +++ G+
Sbjct: 381 RLVLVKMTQAGILFNGQDSEVLNTRGLFFTKYVSEIEADEPGNFTNCRLVLEE-LGLTNA 439
Query: 375 SIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQ 434
+ D +R +C V RAA L ++ A L+ + T+ +DGSV+ P F ++
Sbjct: 440 TDGDCANVRYICECVSKRAAHLVSAGI-ATLINKMDEPTVTVGVDGSVYRFHPKFHNLMV 498
Query: 435 DNINRILGPECDVRAVLAKDGSGIGAAFISAMVVND 470
+ I++++ P +L++DGSG GAA ++A+ +
Sbjct: 499 EKISQLIKPGITFDLMLSEDGSGRGAALVAAVACRE 534
>sp|P17710|HXK1_MOUSE Hexokinase-1 (Hexokinase type I) (HK I) (Hexokinase, tumor isozyme)
Length = 974
Score = 535 bits (1380), Expect = e-150, Method: Composition-based stats.
Identities = 163/462 (35%), Positives = 246/462 (53%), Gaps = 22/462 (4%)
Query: 22 VRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKAD 78
R ++ + + F +S +++ ++ L EM GL +TV+MLPSYV
Sbjct: 517 YRLAEQHRQIEETLSHFRLSKQALMEVKKKLRSEMEMGLRKETNSRATVKMLPSYVRSIP 576
Query: 79 PKRATGVFYALDLGGTNFRVLRVACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIAS 136
G F ALDLGGTNFRVL V + G V+ + IP ++G +LF I S
Sbjct: 577 DGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELFDHIVS 636
Query: 137 NVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQ 196
+ ++ + +PLGFTFSFP +QT ++ G+LI WTKGF G+DV LL+
Sbjct: 637 CISDFLDYMGIKGPR--MPLGFTFSFPCKQTSLDCGILITWTKGFKATDCVGHDVATLLR 694
Query: 197 AAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
A R ++VVA+ NDTVGT+++ +++P ++G+I+GTGSNACY E V
Sbjct: 695 DAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPSCEIGLIVGTGSNACYMEEMKNVEMVEG 754
Query: 256 VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIA 315
INME G F T FD +D+ SLN G+Q EKMISGMYLGEI
Sbjct: 755 ----NQGQMCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIV 810
Query: 316 RRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQ 374
R +++ + L + L RG FE++F I +DR+ LQ R+ +Q+ G+
Sbjct: 811 RNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLALLQ-VRAILQQ-LGL-NS 867
Query: 375 SIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSF 429
+ +D +++ VC +V RAAQL + A + K + T+ +DG++++ P F
Sbjct: 868 TCDDSILVKTVCGVVSKRAAQLCGAGMAAVVQKIRENRGLDHLNVTVGVDGTLYKLHPHF 927
Query: 430 RRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
R++ + L P+C V +L++DGSG GAA I+A+ V +
Sbjct: 928 SRIMHQTVKE-LSPKCTVSFLLSEDGSGKGAALITAVGVRLR 968
Score = 482 bits (1241), Expect = e-134, Method: Composition-based stats.
Identities = 152/443 (34%), Positives = 235/443 (53%), Gaps = 22/443 (4%)
Query: 39 TMSVESMRQIMTYLLYEMVEGLE---GRESTVRMLPSYVYKADPKRATGVFYALDLGGTN 95
+S E + I+T EM GL ++V+MLP++V G F ALDLGG++
Sbjct: 86 RLSDEILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSS 145
Query: 96 FRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRT 153
FR+LRV V + + P+ + G+ + LF +A + ME R +D +
Sbjct: 146 FRILRVQVNHEKSQNVSMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKD--KK 203
Query: 154 VPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALC 212
+P+GFTFSFP Q+K++ VLI WTK F GV+G DV+ LL A + N+VA+
Sbjct: 204 LPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVV 263
Query: 213 NDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGN 272
NDTVGT+++ + D + +VG+IIGTG+NACY E + R IN E G
Sbjct: 264 NDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGR----MCINTEWGA 319
Query: 273 FDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAAL 332
F T+FD ++D SLN G+Q EKM+SGMY+GE+ R ++V ++ + L
Sbjct: 320 FGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKESLLFEGR 379
Query: 333 QTA-LGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRG 391
T L RG F + I D+ G+Q + + + GV+ S +D ++ VC +V
Sbjct: 380 ITPELLTRGKFTTSDVAAIETDK-EGVQNAKEILTR-LGVE-PSHDDCVSVQHVCTIVSF 436
Query: 392 RAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECD 446
R+A L A+ A L + + R T+ +DGS+++ P + R + R++ P+ D
Sbjct: 437 RSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKMHPQYSRRFHKTLRRLV-PDSD 495
Query: 447 VRAVLAKDGSGIGAAFISAMVVN 469
VR +L++ GSG GAA ++A+
Sbjct: 496 VRFLLSESGSGKGAAMVTAVAYR 518
>ref|NP_034568.1| hexokinase 1 [Mus musculus]
gb|AAB57759.1| hexokinase [Mus musculus]
Length = 945
Score = 535 bits (1379), Expect = e-150, Method: Composition-based stats.
Identities = 163/462 (35%), Positives = 246/462 (53%), Gaps = 22/462 (4%)
Query: 22 VRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKAD 78
R ++ + + F +S +++ ++ L EM GL +TV+MLPSYV
Sbjct: 488 YRLAEQHRQIEETLSHFRLSKQALMEVKKKLRSEMEMGLRKETNSRATVKMLPSYVRSIP 547
Query: 79 PKRATGVFYALDLGGTNFRVLRVACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIAS 136
G F ALDLGGTNFRVL V + G V+ + IP ++G +LF I S
Sbjct: 548 DGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELFDHIVS 607
Query: 137 NVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQ 196
+ ++ + +PLGFTFSFP +QT ++ G+LI WTKGF G+DV LL+
Sbjct: 608 CISDFLDYMGIKGPR--MPLGFTFSFPCKQTSLDCGILITWTKGFKATDCVGHDVATLLR 665
Query: 197 AAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
A R ++VVA+ NDTVGT+++ +++P ++G+I+GTGSNACY E V
Sbjct: 666 DAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPSCEIGLIVGTGSNACYMEEMKNVEMVEG 725
Query: 256 VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIA 315
INME G F T FD +D+ SLN G+Q EKMISGMYLGEI
Sbjct: 726 ----NQGQMCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIV 781
Query: 316 RRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQ 374
R +++ + L + L RG FE++F I +DR+ LQ R+ +Q+ G+
Sbjct: 782 RNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLALLQ-VRAILQQ-LGL-NS 838
Query: 375 SIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSF 429
+ +D +++ VC +V RAAQL + A + K + T+ +DG++++ P F
Sbjct: 839 TCDDSILVKTVCGVVSKRAAQLCGAGMAAVVQKIRENRGLDHLNVTVGVDGTLYKLHPHF 898
Query: 430 RRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
R++ + L P+C V +L++DGSG GAA I+A+ V +
Sbjct: 899 SRIMHQTVKE-LSPKCTVSFLLSEDGSGKGAALITAVGVRLR 939
Score = 471 bits (1213), Expect = e-131, Method: Composition-based stats.
Identities = 151/465 (32%), Positives = 233/465 (50%), Gaps = 43/465 (9%)
Query: 39 TMSVESMRQIMTYLLYEMVEGLE---GRESTVRMLPSYVYKADPKRATGVFYALDLGGTN 95
+S E + I+T EM GL ++V+MLP++V G F ALDLGG++
Sbjct: 34 RLSDEILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSS 93
Query: 96 FRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRT 153
FR+LRV V + + P+ + G+ + LF +A + ME R +D +
Sbjct: 94 FRILRVQVNHEKSQNVSMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKD--KK 151
Query: 154 VPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALC 212
+P+GFTFSFP Q+K++ VLI WTK F GV+G DV+ LL A + N+VA+
Sbjct: 152 LPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVV 211
Query: 213 NDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGN 272
NDTVGT+++ + D + +VG+IIGTG+NACY E + R IN E G
Sbjct: 212 NDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGR----MCINTEWGA 267
Query: 273 FDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAAL 332
F T+FD ++D SLN G+Q EKM+SGMY+GE+ R ++V ++ + L
Sbjct: 268 FGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKESLLFEGR 327
Query: 333 QTA-LGNRGSFESRFAGMIS----------------------ADRMPGLQFTRSTIQKVC 369
T L RG F + I G+Q + + +
Sbjct: 328 ITPELLTRGKFTTSDVAAIETGWELSPDRRWYQAYMRCTQDTHRDKEGVQNAKEILTR-L 386
Query: 370 GVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFE 424
GV+ S +D ++ VC +V R+A L A+ A L + + R T+ +DGS+++
Sbjct: 387 GVE-PSHDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYK 445
Query: 425 KIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
P + R + R++ P+ DVR +L++ GSG GAA ++A+
Sbjct: 446 MHPQYSRRFHKTLRRLV-PDSDVRFLLSESGSGKGAAMVTAVAYR 489
>ref|NP_989543.1| hexokinase 2 [Gallus gallus]
dbj|BAC20933.1| hexokinase2 [Gallus gallus]
Length = 916
Score = 535 bits (1379), Expect = e-150, Method: Composition-based stats.
Identities = 166/462 (35%), Positives = 254/462 (54%), Gaps = 22/462 (4%)
Query: 22 VRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGR---ESTVRMLPSYVYKAD 78
R + A + +S E + ++ + EM +GL E+TV+MLP+YV
Sbjct: 461 YRLAAQHKARQKILEALKLSHEQLLEVKRRMRVEMEKGLGKETHAEATVKMLPTYVCSTP 520
Query: 79 PKRATGVFYALDLGGTNFRVLRVACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIAS 136
G F ALDLGGTNFRVL V + G V+ + IP ++G +LF I
Sbjct: 521 DGTEKGDFLALDLGGTNFRVLLVRVRNGMRRGVEMHNKIYSIPLEVMQGTGEELFDHIVH 580
Query: 137 NVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQ 196
+ +E + + ++PLGFTFSFP +QT ++ G+L++WTKGF G +G DV++LL+
Sbjct: 581 CISDFLEYMGMKGV--SLPLGFTFSFPCKQTNLDEGILLKWTKGFKATGCEGEDVVSLLK 638
Query: 197 AAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
A R ++VVA+ NDTVGT+++ ++DP +VG+I+GTGSNACY E V
Sbjct: 639 EAIHRREEFDLDVVAVVNDTVGTMMTCGYEDPYCEVGLIVGTGSNACYMEEMRNVELVEG 698
Query: 256 VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIA 315
R +NME G F T+FDL +D+ SLN G+Q EKMISGMYLGEI
Sbjct: 699 DEGR----MCVNMEWGAFGDNGCLDDIQTEFDLAVDELSLNPGKQRFEKMISGMYLGEIV 754
Query: 316 RRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQ 374
R +++ + L + L RG FE++F I +D + LQ RS +Q G++
Sbjct: 755 RNILMDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQ-VRSILQ-HLGLE-S 811
Query: 375 SIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSF 429
+ +D I+++VC +V RAAQL + A + K + + T+ +DG++++ P F
Sbjct: 812 TCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDKIRENRGLDFLKVTVGVDGTLYKLHPHF 871
Query: 430 RRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
++QD + + L P C+V + ++DGSG GAA I+A+ +
Sbjct: 872 SAIMQDTVRQ-LSPCCEVTFLQSEDGSGKGAALITAVACRIR 912
Score = 517 bits (1333), Expect = e-145, Method: Composition-based stats.
Identities = 160/443 (36%), Positives = 244/443 (55%), Gaps = 22/443 (4%)
Query: 39 TMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTN 95
+S ++++++ EM +GL ++V+MLPS+V G F ALDLGGTN
Sbjct: 30 RLSEDTLQEVSERFRKEMEKGLGADTNPTASVKMLPSFVRSTPDGTEDGDFLALDLGGTN 89
Query: 96 FRVLRVACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRT 153
FRVLRV + V+ + ++I + + G+ LF IA + ME +D +
Sbjct: 90 FRVLRVKVSDNGLQKVEMESQIYEIHEDLMRGSGMQLFDHIAECLGNFMEKLKIKD--KK 147
Query: 154 VPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALC 212
+PLGFTFSFP QTK++ +L+ WTKGF V+G DV++LL+ A + +++VA+
Sbjct: 148 LPLGFTFSFPCHQTKLDESILVNWTKGFKCSSVEGKDVVSLLRRAIKKRGDFDIDIVAVV 207
Query: 213 NDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGN 272
NDTVGT++S + D +VG+I+GTG+NACY E + R INME G
Sbjct: 208 NDTVGTMMSCGYDDQNCEVGLIVGTGTNACYMEEMRHIDLVEGDEGR----MCINMEWGA 263
Query: 273 FDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AA 331
F T+FD +ID SLN G+Q EKMISGMY+GE+ R ++V ++ L
Sbjct: 264 FGDDGALNDIRTEFDHEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKEGLLFQGK 323
Query: 332 LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRG 391
L + L G FE+RF I ++ GLQ + K G++ S ED +C++V
Sbjct: 324 LSSDLRTTGHFETRFVSAIEKEK-EGLQKAHEILTK-LGLE-PSHEDCLATHRICQIVST 380
Query: 392 RAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECD 446
R+A L + A L + + R+T+ +DGSV++K P F R L + ++L P+C+
Sbjct: 381 RSANLCGATLAARLRRIKEYKGVDPLRSTVGVDGSVYKKYPHFARRLHKTVRKLL-PDCE 439
Query: 447 VRAVLAKDGSGIGAAFISAMVVN 469
+R V ++DGSG GAA ++A+
Sbjct: 440 IRFVRSEDGSGKGAAMVTAVAYR 462
>dbj|BAF83046.1| unnamed protein product [Homo sapiens]
Length = 917
Score = 535 bits (1378), Expect = e-150, Method: Composition-based stats.
Identities = 159/462 (34%), Positives = 247/462 (53%), Gaps = 22/462 (4%)
Query: 22 VRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGR---ESTVRMLPSYVYKAD 78
R + A +S + + ++ + EM GL + V+MLP+YV
Sbjct: 461 YRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHAGAPVKMLPTYVCATP 520
Query: 79 PKRATGVFYALDLGGTNFRVLRVACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIAS 136
G F ALDLGGTNFRVL V + G V+ + IP+ + G +LF I
Sbjct: 521 DGTEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQ 580
Query: 137 NVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQ 196
+ +E + + ++PLGFTFSFP +Q ++ +L++WTKGF G +G DV+ LL+
Sbjct: 581 CIADFLEYMGMKGV--SLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLK 638
Query: 197 AAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
A R ++VVA+ NDTVGT+++ F+DP +VG+I+GTGSNACY E V
Sbjct: 639 EAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEG 698
Query: 256 VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIA 315
R +NME G F T+FD+ +D+ SLN G+Q EKMISGMYLGEI
Sbjct: 699 EEGR----MCVNMEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIV 754
Query: 316 RRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQ 374
R +++ + L + L RG FE++F I +D + LQ R+ +Q G++
Sbjct: 755 RNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQ-VRAILQ-HLGLE-S 811
Query: 375 SIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSF 429
+ +D I+++VC +V RAAQL + A + + + + T+ +DG++++ P F
Sbjct: 812 TCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHF 871
Query: 430 RRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
+V+ + + L P+CDV + ++DGSG GAA I+A+ +
Sbjct: 872 AKVMHETVKD-LAPKCDVSFLQSEDGSGKGAALITAVACRIR 912
Score = 516 bits (1330), Expect = e-144, Method: Composition-based stats.
Identities = 161/457 (35%), Positives = 244/457 (53%), Gaps = 22/457 (4%)
Query: 25 VKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKR 81
+ + +S E++ +I EM +GL + V+MLP++V
Sbjct: 16 HDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGT 75
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASNVK 139
G F ALDLGGTNFRVL V + V+ + IP+ + G+ T LF IA +
Sbjct: 76 EHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLA 135
Query: 140 KTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAF 199
M+ +D + +PLGFTFSFP QTK++ L+ WTKGF + GV+G DV+AL++ A
Sbjct: 136 NFMDKLHIKD--KKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAI 193
Query: 200 GRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAA 258
R +++VA+ NDTVGT+++ + D ++G+I+GTGSNACY E +
Sbjct: 194 QRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEG 253
Query: 259 RGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRV 318
R INME G F T+FD +ID SLN G+Q EKMISGMY+GE+ R +
Sbjct: 254 R----MCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLI 309
Query: 319 IVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+V ++ L L L N G FE++ I ++ G++ R + + G+D + E
Sbjct: 310 LVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEK-DGIRKAREVLMR-LGLD-PTQE 366
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRV 432
D +C++V R+A L A+ A L + + R+TI +DGSV++K P F +
Sbjct: 367 DCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKR 426
Query: 433 LQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
L + R++ P CDVR + ++DGSG GAA ++A+
Sbjct: 427 LHKTVRRLV-PGCDVRFLRSEDGSGKGAAMVTAVAYR 462
>gb|AAY24209.1| unknown [Homo sapiens]
Length = 573
Score = 535 bits (1378), Expect = e-150, Method: Composition-based stats.
Identities = 159/462 (34%), Positives = 247/462 (53%), Gaps = 22/462 (4%)
Query: 22 VRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKAD 78
R + A +S + + ++ + EM GL + V+MLP+YV
Sbjct: 117 YRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATP 176
Query: 79 PKRATGVFYALDLGGTNFRVLRVACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIAS 136
G F ALDLGGTNFRVL V + G V+ + IP+ + G +LF I
Sbjct: 177 DGTEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQ 236
Query: 137 NVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQ 196
+ +E + + ++PLGFTFSFP +Q ++ +L++WTKGF G +G DV+ LL+
Sbjct: 237 CIADFLEYMGMKGV--SLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLK 294
Query: 197 AAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
A R ++VVA+ NDTVGT+++ F+DP +VG+I+GTGSNACY E V
Sbjct: 295 EAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEG 354
Query: 256 VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIA 315
R +NME G F T+FD+ +D+ SLN G+Q EKMISGMYLGEI
Sbjct: 355 EEGR----MCVNMEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIV 410
Query: 316 RRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQ 374
R +++ + L + L RG FE++F I +D + LQ R+ +Q G++
Sbjct: 411 RNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQ-VRAILQ-HLGLE-S 467
Query: 375 SIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSF 429
+ +D I+++VC +V RAAQL + A + + + + T+ +DG++++ P F
Sbjct: 468 TCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHF 527
Query: 430 RRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
+V+ + + L P+CDV + ++DGSG GAA I+A+ +
Sbjct: 528 AKVMHETVKD-LAPKCDVSFLQSEDGSGKGAALITAVACRIR 568
Score = 134 bits (338), Expect = 2e-29, Method: Composition-based stats.
Identities = 39/119 (32%), Positives = 66/119 (55%), Gaps = 8/119 (6%)
Query: 356 PGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG--- 412
G++ R + + G+D + ED +C++V R+A L A+ A L + +
Sbjct: 3 DGIRKAREVLMR-LGLD-PTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEE 60
Query: 413 --RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
R+TI +DGSV++K P F + L + R++ P CDVR + ++DGSG GAA ++A+
Sbjct: 61 RLRSTIGVDGSVYKKHPHFAKRLHKTVRRLV-PGCDVRFLRSEDGSGKGAAMVTAVAYR 118
>gb|AAV32455.1| hexokinase [Leishmania infantum]
Length = 451
Score = 535 bits (1378), Expect = e-150, Method: Composition-based stats.
Identities = 281/451 (62%), Positives = 352/451 (78%)
Query: 18 DGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKA 77
D E +R +K+ +A+A+L QFTMS E M+Q+ Y+++EMVEGLEGR STVRMLPS+VY +
Sbjct: 1 DSEEMRYIKQRLALASLATQFTMSSEKMKQLTMYMIHEMVEGLEGRPSTVRMLPSFVYTS 60
Query: 78 DPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASN 137
DP +ATGV+YALDLGGTNFRVLRV+ + G V D + S F IPK AL G+ATDLF FIA +
Sbjct: 61 DPAKATGVYYALDLGGTNFRVLRVSLRGGKVDDRTDSKFVIPKSALVGDATDLFDFIAQS 120
Query: 138 VKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQA 197
VKK M AP+DL + VPLGFTFSFPV+Q VN+G+LI+WTKGFSTK V+GNDV+ LLQA
Sbjct: 121 VKKMMSENAPDDLEKRVPLGFTFSFPVDQKAVNKGLLIKWTKGFSTKNVEGNDVVELLQA 180
Query: 198 AFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVA 257
+ RV + VNVVALCNDTVGTL++ YF D +VQVGVIIGTGSNACYFE ASAVTKDPAV+
Sbjct: 181 SLRRVRVNVNVVALCNDTVGTLVARYFVDTDVQVGVIIGTGSNACYFERASAVTKDPAVS 240
Query: 258 ARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARR 317
ARG+A+TPINME GNFDSKY++ LP T +D ++D + N+ Q EK++SGMYLGEI+RR
Sbjct: 241 ARGNAVTPINMECGNFDSKYKYALPITVYDDEMDAITPNRENQRQEKLVSGMYLGEISRR 300
Query: 318 VIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+IVHL+ + CLP L L +FES+ GMI+AD+MPGLQFTR I+++ GVDV +
Sbjct: 301 LIVHLAQLGCLPRGLVDGLCRPWAFESKHMGMIAADQMPGLQFTRELIKRIAGVDVTDMS 360
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNI 437
DL IR+ C LVR RAAQ A F AP++KT+TQG AT+A+DGSV+EK PSF+R+ Q+ I
Sbjct: 361 DLHTIREACCLVRNRAAQQGAVFTAAPMLKTRTQGLATVAVDGSVYEKTPSFQRLYQECI 420
Query: 438 NRILGPECDVRAVLAKDGSGIGAAFISAMVV 468
ILG +V+ VL KDGSG+GAA I A+
Sbjct: 421 TSILGSTSNVKVVLQKDGSGVGAAMICALAA 451
>gb|EDL32103.1| hexokinase 1, isoform CRA_a [Mus musculus]
Length = 945
Score = 534 bits (1377), Expect = e-150, Method: Composition-based stats.
Identities = 163/462 (35%), Positives = 246/462 (53%), Gaps = 22/462 (4%)
Query: 22 VRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKAD 78
R ++ + + F +S +++ ++ L EM GL +TV+MLPSYV
Sbjct: 488 YRLAEQHRQIEETLSHFRLSKQALMEVKKKLRSEMEMGLRKETNSRATVKMLPSYVRSIP 547
Query: 79 PKRATGVFYALDLGGTNFRVLRVACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIAS 136
G F ALDLGGTNFRVL V + G V+ + IP ++G +LF I S
Sbjct: 548 DGTEHGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYSIPLEIMQGTGDELFDHIVS 607
Query: 137 NVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQ 196
+ ++ + +PLGFTFSFP +QT ++ G+LI WTKGF G+DV LL+
Sbjct: 608 CISDFLDYMGIKGPR--MPLGFTFSFPCKQTSLDCGILITWTKGFKATDCVGHDVATLLR 665
Query: 197 AAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
A R ++VVA+ NDTVGT+++ +++P ++G+I+GTGSNACY E V
Sbjct: 666 DAVKRREEFDLDVVAVVNDTVGTMMTCAYEEPSCEIGLIVGTGSNACYMEEMKNVEMVEG 725
Query: 256 VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIA 315
INME G F T FD +D+ SLN G+Q EKMISGMYLGEI
Sbjct: 726 ----NQGQMCINMEWGAFGDNGCLDDIRTDFDKVVDEYSLNSGKQRFEKMISGMYLGEIV 781
Query: 316 RRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQ 374
R +++ + L + L RG FE++F I +DR+ LQ R+ +Q+ G+
Sbjct: 782 RNILIDFTKKGFLFRGQISEPLKTRGIFETKFLSQIESDRLALLQ-VRAILQQ-LGL-NS 838
Query: 375 SIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSF 429
+ +D +++ VC +V RAAQL + A + K + T+ +DG++++ P F
Sbjct: 839 TCDDSILVKTVCGVVSKRAAQLCGAGMAAVVEKIRENRGLDHLNVTVGVDGTLYKLHPHF 898
Query: 430 RRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
R++ + L P+C V +L++DGSG GAA I+A+ V +
Sbjct: 899 SRIMHQTVKE-LSPKCTVSFLLSEDGSGKGAALITAVGVRLR 939
Score = 471 bits (1212), Expect = e-131, Method: Composition-based stats.
Identities = 151/465 (32%), Positives = 233/465 (50%), Gaps = 43/465 (9%)
Query: 39 TMSVESMRQIMTYLLYEMVEGLE---GRESTVRMLPSYVYKADPKRATGVFYALDLGGTN 95
+S E + I+T EM GL ++V+MLP++V G F ALDLGG++
Sbjct: 34 RLSDEILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSS 93
Query: 96 FRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRT 153
FR+LRV V + + P+ + G+ + LF +A + ME R +D +
Sbjct: 94 FRILRVQVNHEKSQNVSMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKD--KK 151
Query: 154 VPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALC 212
+P+GFTFSFP Q+K++ VLI WTK F GV+G DV+ LL A + N+VA+
Sbjct: 152 LPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVV 211
Query: 213 NDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGN 272
NDTVGT+++ + D + +VG+IIGTG+NACY E + R IN E G
Sbjct: 212 NDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGR----MCINTEWGA 267
Query: 273 FDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLPAAL 332
F T+FD ++D SLN G+Q EKM+SGMY+GE+ R ++V ++ + L
Sbjct: 268 FGDDGSLEDIRTEFDRELDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKESLLFEGR 327
Query: 333 QTA-LGNRGSFESRFAGMIS----------------------ADRMPGLQFTRSTIQKVC 369
T L RG F + I G+Q + + +
Sbjct: 328 ITPELLTRGKFTTSDVAAIETGWELSPDRRWYQAYMRCTQDTHRDKEGVQNAKEILTR-L 386
Query: 370 GVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFE 424
GV+ S +D ++ VC +V R+A L A+ A L + + R T+ +DGS+++
Sbjct: 387 GVE-PSHDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYK 445
Query: 425 KIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
P + R + R++ P+ DVR +L++ GSG GAA ++A+
Sbjct: 446 MHPQYSRRFHKTLRRLV-PDSDVRFLLSESGSGKGAAMVTAVAYR 489
>gb|AAA41334.1| hexokinase type II
Length = 516
Score = 534 bits (1377), Expect = e-150, Method: Composition-based stats.
Identities = 159/462 (34%), Positives = 248/462 (53%), Gaps = 22/462 (4%)
Query: 22 VRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKAD 78
R + A +S E + ++ + EM +GL + V+MLP+YV
Sbjct: 60 YRLADQHRARQKTLESLKLSHEQLLEVKRRMKVEMEQGLSKETHAVAPVKMLPTYVCATP 119
Query: 79 PKRATGVFYALDLGGTNFRVLRVACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIAS 136
G F ALDLGGTNFRVL V + G V+ + IP+ + G +LF I
Sbjct: 120 DGTEKGDFLALDLGGTNFRVLLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGEELFDHIVQ 179
Query: 137 NVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQ 196
+ +E + + ++PLGFTFSFP +Q +++ +L++WTKGF G +G DV+ LL+
Sbjct: 180 CIADFLEYMGMKGV--SLPLGFTFSFPCQQNSLDQSILLKWTKGFKASGCEGEDVVTLLK 237
Query: 197 AAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
A R ++VVA+ NDTVGT+++ ++DP +VG+I+GTGSNACY E V
Sbjct: 238 EAIHRREEFDLDVVAVVNDTVGTMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVDG 297
Query: 256 VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIA 315
R +NME G F T FD+ +D+ SLN G+Q EKMISGMYLGEI
Sbjct: 298 EEGR----MCVNMEWGAFGDNGCLDDLRTVFDVAVDELSLNPGKQRFEKMISGMYLGEIV 353
Query: 316 RRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQ 374
R +++ + L + L RG FE++F I +D + LQ R+ + + G++
Sbjct: 354 RNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQ-VRAIL-RHLGLE-S 410
Query: 375 SIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSF 429
+ +D I+++VC +V RAAQL + A + K + + T+ +DG++++ P F
Sbjct: 411 TCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDKIRENRGLDNLKVTVGVDGTLYKLHPHF 470
Query: 430 RRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
+V+ + + L P+CDV + ++DGSG GAA I+A+ +
Sbjct: 471 AKVMHETVRD-LAPKCDVSFLESEDGSGKGAALITAVACRIR 511
Score = 92.2 bits (228), Expect = 8e-17, Method: Composition-based stats.
Identities = 25/61 (40%), Positives = 42/61 (68%), Gaps = 1/61 (1%)
Query: 409 QTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVV 468
+ + R+TI +DGSV++K P F + L + R++ P+CDVR + ++DGSG GAA ++A+
Sbjct: 2 EERLRSTIGVDGSVYKKHPHFAKRLHKAVRRLV-PDCDVRFLRSEDGSGKGAAMVTAVAY 60
Query: 469 N 469
Sbjct: 61 R 61
>ref|XP_870563.2| PREDICTED: similar to hexokinase II [Bos taurus]
Length = 584
Score = 534 bits (1376), Expect = e-150, Method: Composition-based stats.
Identities = 159/462 (34%), Positives = 245/462 (53%), Gaps = 22/462 (4%)
Query: 22 VRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKAD 78
R + A +S E + ++ + EM GL + V+MLP+YV
Sbjct: 128 YRLADQHRARQKTLESLKLSREQLLEVKRRMKIEMERGLSKETHAIAPVKMLPTYVCATP 187
Query: 79 PKRATGVFYALDLGGTNFRVLRVACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIAS 136
G F ALDLGGTNFRVL V + G V+ + IP+ + G +LF I
Sbjct: 188 DGTEKGDFLALDLGGTNFRVLLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGDELFDHIVQ 247
Query: 137 NVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQ 196
+ +E + + ++PLGFTFSFP +Q ++ +L++WTKGF G +G DV+ LL+
Sbjct: 248 CIADFLEYMGMKGV--SLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVMLLK 305
Query: 197 AAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
A R ++VVA+ NDTVGT+++ ++DP +VG+I+GTGSNACY E V
Sbjct: 306 EAIHRREEFDLDVVAVVNDTVGTMMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEG 365
Query: 256 VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIA 315
R +NME G F T+FD +D+ SLN G+Q EKMISGMYLGEI
Sbjct: 366 EEGR----MCVNMEWGAFGDNGCLDDLRTEFDAAVDELSLNPGRQRFEKMISGMYLGEIV 421
Query: 316 RRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQ 374
R +++ + L + L RG FE++F I +D + LQ R+ + G++
Sbjct: 422 RNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQ-VRAIL-HHLGLE-S 478
Query: 375 SIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSF 429
+ +D I+++VC +V RAAQL + A + K + + T+ +DG++++ P F
Sbjct: 479 TCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDKIRENRGLDTLKVTVGVDGTLYKLHPHF 538
Query: 430 RRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
+V+ + + L P+CDV + ++DGSG GAA I+A+ +
Sbjct: 539 AKVMHETVKD-LAPKCDVSFLESEDGSGKGAALITAVACRIR 579
Score = 134 bits (338), Expect = 1e-29, Method: Composition-based stats.
Identities = 40/119 (33%), Positives = 67/119 (56%), Gaps = 8/119 (6%)
Query: 356 PGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG--- 412
G+Q R + + G+D + ED VC++V R+A L A+ A L + +
Sbjct: 14 DGIQKAREILVR-LGLD-PTHEDCVATHRVCQIVSTRSASLCAATLAAVLWRIKENKGVD 71
Query: 413 --RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
R+T+ +DGSV++K P F + L + R++ P+CDVR + ++DGSG GAA ++A+
Sbjct: 72 RLRSTVGVDGSVYKKHPHFAKRLHKTVRRLV-PDCDVRFLRSEDGSGKGAAMVTAVAYR 129
>ref|XP_001381777.1| PREDICTED: similar to hexokinase II [Monodelphis domestica]
Length = 917
Score = 534 bits (1376), Expect = e-150, Method: Composition-based stats.
Identities = 166/474 (35%), Positives = 252/474 (53%), Gaps = 27/474 (5%)
Query: 15 QGNDGETVRAVKRDVAMAALTNQ-----FTMSVESMRQIMTYLLYEMVEGLEGRE---ST 66
G V AV +A Q +S + + ++ + EM GL ++
Sbjct: 449 SGKGAAMVTAVAYRLADQHRARQKTLEALKLSYDQLLEVKKRMKREMERGLSKETHAAAS 508
Query: 67 VRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEG--AVVDSSTSAFKIPKYALE 124
V+MLP+YV G F ALDLGGTNFRVL V + G V+ + IP+ +
Sbjct: 509 VKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLVRVRNGMRRGVEMHNKIYAIPQEVMH 568
Query: 125 GNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTK 184
G +LF I + +E + + ++PLGFTFSFP +Q ++ +L++WTKGF
Sbjct: 569 GTGDELFDHIVQCIADFLEYMGMKGV--SLPLGFTFSFPCQQNSLDESILLKWTKGFKAT 626
Query: 185 GVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACY 243
G G DV+ LL+ A R ++VVA+ NDTVGT+++ ++DP +VG+I+GTGSNACY
Sbjct: 627 GCVGEDVVGLLKDAIHRREEFDLDVVAVVNDTVGTMMTCGYEDPHCEVGLIVGTGSNACY 686
Query: 244 FETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALE 303
E V R INME G F + T+FDL +D+ SLN G+Q E
Sbjct: 687 MEEMRNVELVEGDDGR----MCINMEWGAFGDEGCLDDIRTEFDLAVDELSLNPGKQRFE 742
Query: 304 KMISGMYLGEIARRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTR 362
KMISGMYLGEI R ++++ + L + L RG FE++F I +D + LQ
Sbjct: 743 KMISGMYLGEIVRNILINFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQV-- 800
Query: 363 STIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIA 417
TI + G++ + +D I+++VC +V RAAQL + A + K + + TI
Sbjct: 801 RTILRHLGLE-STCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDKIRENRQLDSLKVTIG 859
Query: 418 IDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
+DG++++ P F +V+ + + L P+CDV + ++DGSG GAA I+A+ +
Sbjct: 860 VDGTLYKLHPHFAKVMHETVKE-LAPKCDVSFLESEDGSGKGAALITAVACRIR 912
Score = 510 bits (1313), Expect = e-142, Method: Composition-based stats.
Identities = 157/457 (34%), Positives = 244/457 (53%), Gaps = 22/457 (4%)
Query: 25 VKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKR 81
+ + +S E+++++ EM +GL ++V+MLP++V
Sbjct: 16 HDQVQKVDQYLYHMRLSDETLQEVSKRFRKEMEKGLGADTHPTASVKMLPTFVRSTPDGT 75
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASNVK 139
G F ALDLGGTNFRVLRV + V+ + IP+ + G+ T LF IA +
Sbjct: 76 EDGDFLALDLGGTNFRVLRVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIADCLA 135
Query: 140 KTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAF 199
M+ + N+ +PLGFTFSFP QTK++ L+ WTKGF + GV+G DV++L++ A
Sbjct: 136 NFMDKLQIK--NKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVSLIRKAI 193
Query: 200 GRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAA 258
R +++VA+ NDTVGT+++ + D ++G+I+GTG+NACY E +
Sbjct: 194 QRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGTNACYMEEMRYIDAVEGDEG 253
Query: 259 RGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRV 318
R INME G F T+FD +ID SLN G+Q EKMISGMY+GE+ R +
Sbjct: 254 R----MCINMEWGAFGDDGVLDDIRTEFDREIDMGSLNPGKQLFEKMISGMYMGELVRLI 309
Query: 319 IVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+V ++ L L L G FE++ I ++ G++ + + G+ S E
Sbjct: 310 LVKMAKEEMLFGGKLSPDLLTTGRFETKDVSDIEGEK-DGIKKALDILTR-LGLQ-PSQE 366
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRV 432
D +C++V R+A L A+ A L + + R+TI +DGSV++K P F
Sbjct: 367 DCVATHRICQIVSTRSANLCAATLAAVLRRLKENKGDDRLRSTIGVDGSVYKKHPHFATR 426
Query: 433 LQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
L + R++ P+CDVR + ++DGSG GAA ++A+
Sbjct: 427 LHKAVRRLV-PDCDVRFLRSEDGSGKGAAMVTAVAYR 462
>ref|NP_000180.2| hexokinase 2 [Homo sapiens]
sp|P52789|HXK2_HUMAN Hexokinase-2 (Hexokinase type II) (HK II) (Muscle form hexokinase)
gb|AAD30174.1|AF148513_1 hexokinase II [Homo sapiens]
gb|AAH21116.1| Hexokinase 2 [Homo sapiens]
gb|AAH64369.1| Hexokinase 2 [Homo sapiens]
gb|AAT38114.1| hexokinase 2 [Homo sapiens]
gb|EAW99601.1| hexokinase 2, isoform CRA_a [Homo sapiens]
gb|EAW99602.1| hexokinase 2, isoform CRA_a [Homo sapiens]
gb|ABM86696.1| hexokinase 2 [synthetic construct]
gb|ABW03812.1| hexokinase 2 [synthetic construct]
dbj|BAG10585.1| hexokinase-2 [synthetic construct]
Length = 917
Score = 534 bits (1376), Expect = e-150, Method: Composition-based stats.
Identities = 159/462 (34%), Positives = 247/462 (53%), Gaps = 22/462 (4%)
Query: 22 VRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKAD 78
R + A +S + + ++ + EM GL + V+MLP+YV
Sbjct: 461 YRLADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATP 520
Query: 79 PKRATGVFYALDLGGTNFRVLRVACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIAS 136
G F ALDLGGTNFRVL V + G V+ + IP+ + G +LF I
Sbjct: 521 DGTEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQ 580
Query: 137 NVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQ 196
+ +E + + ++PLGFTFSFP +Q ++ +L++WTKGF G +G DV+ LL+
Sbjct: 581 CIADFLEYMGMKGV--SLPLGFTFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLK 638
Query: 197 AAFGRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
A R ++VVA+ NDTVGT+++ F+DP +VG+I+GTGSNACY E V
Sbjct: 639 EAIHRREEFDLDVVAVVNDTVGTMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEG 698
Query: 256 VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIA 315
R +NME G F T+FD+ +D+ SLN G+Q EKMISGMYLGEI
Sbjct: 699 EEGR----MCVNMEWGAFGDNGCLDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIV 754
Query: 316 RRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQ 374
R +++ + L + L RG FE++F I +D + LQ R+ +Q G++
Sbjct: 755 RNILIDFTKRGLLFRGRISERLKTRGIFETKFLSQIESDCLALLQ-VRAILQ-HLGLE-S 811
Query: 375 SIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSF 429
+ +D I+++VC +V RAAQL + A + + + + T+ +DG++++ P F
Sbjct: 812 TCDDSIIVKEVCTVVARRAAQLCGAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHF 871
Query: 430 RRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
+V+ + + L P+CDV + ++DGSG GAA I+A+ +
Sbjct: 872 AKVMHETVKD-LAPKCDVSFLQSEDGSGKGAALITAVACRIR 912
Score = 514 bits (1325), Expect = e-144, Method: Composition-based stats.
Identities = 161/457 (35%), Positives = 244/457 (53%), Gaps = 22/457 (4%)
Query: 25 VKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKR 81
+ + +S E++ +I EM +GL + V+MLP++V
Sbjct: 16 HDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGT 75
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASNVK 139
G F ALDLGGTNFRVL V + V+ + IP+ + G+ T LF IA +
Sbjct: 76 EHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLA 135
Query: 140 KTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAF 199
M+ +D + +PLGFTFSFP QTK++ L+ WTKGF + GV+G DV+AL++ A
Sbjct: 136 NFMDKLQIKD--KKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAI 193
Query: 200 GRVS-LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAA 258
R +++VA+ NDTVGT+++ + D ++G+I+GTGSNACY E +
Sbjct: 194 QRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEG 253
Query: 259 RGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRV 318
R INME G F T+FD +ID SLN G+Q EKMISGMY+GE+ R +
Sbjct: 254 R----MCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLI 309
Query: 319 IVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+V ++ L L L N G FE++ I ++ G++ R + + G+D + E
Sbjct: 310 LVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEK-DGIRKAREVLMR-LGLD-PTQE 366
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRV 432
D +C++V R+A L A+ A L + + R+TI +DGSV++K P F +
Sbjct: 367 DCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKR 426
Query: 433 LQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
L + R++ P CDVR + ++DGSG GAA ++A+
Sbjct: 427 LHKTVRRLV-PGCDVRFLRSEDGSGKGAAMVTAVAYR 462
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
gb|AAY83348.1| hexokinase [Hypocrea jecorina] 576 e-162
ref|XP_749720.1| hexokinase Kxk [Aspergillus fumigatus Af29... 574 e-162
ref|XP_001260212.1| hexokinase Kxk, putative [Neosartorya f... 574 e-162
ref|XP_380676.1| hypothetical protein FG00500.1 [Gibberella... 574 e-162
ref|XP_965673.2| hexokinase [Neurospora crassa OR74A] >gi|1... 573 e-161
ref|XP_001912895.1| unnamed protein product [Podospora anse... 572 e-161
ref|XP_001597079.1| hypothetical protein SS1G_01273 [Sclero... 572 e-161
gb|ABY89285.1| putative hexokinase HXK1 [Gibberella monilif... 572 e-161
ref|XP_001549109.1| hexokinase [Botryotinia fuckeliana B05.... 569 e-160
ref|XP_001247226.1| hexokinase [Coccidioides immitis RS] >g... 568 e-160
ref|XP_364444.1| hexokinase [Magnaporthe grisea 70-15] >gi|... 568 e-160
ref|XP_001275241.1| hexokinase Kxk, putative [Aspergillus c... 567 e-160
ref|XP_001819202.1| hypothetical protein [Aspergillus oryza... 563 e-158
ref|XP_001386689.2| Hexokinase [Pichia stipitis CBS 6054] >... 561 e-158
ref|XP_001215959.1| hexokinase [Aspergillus terreus NIH2624... 560 e-158
gb|AAG28789.1|AF309088_1 hexokinase [Tuber borchii] 559 e-157
ref|XP_717405.1| hexokinase II [Candida albicans SC5314] >g... 559 e-157
emb|CAC69958.1| hexokinase [Trypanosoma brucei] 557 e-157
gb|EDU44499.1| hexokinase [Pyrenophora tritici-repentis Pt-... 557 e-157
ref|XP_822456.1| hexokinase [Trypanosoma brucei TREU927] >g... 555 e-156
ref|XP_001502742.1| PREDICTED: similar to hexokinase domain... 555 e-156
ref|XP_460972.1| hypothetical protein DEHA0F15169g [Debaryo... 555 e-156
gb|AAA34697.1| hexokinase P-II peptide >gi|224664|prf||1110... 554 e-156
gb|AAA34699.1| hexokinase (HXK2) 553 e-155
ref|XP_453567.1| HXK_KLULA [Kluyveromyces lactis] >gi|38605... 552 e-155
ref|NP_079406.3| hexokinase domain containing 1 [Homo sapie... 552 e-155
dbj|BAF83713.1| unnamed protein product [Homo sapiens] 552 e-155
ref|XP_001660030.1| hexokinase [Aedes aegypti] >gi|10887452... 551 e-155
ref|XP_001110556.1| PREDICTED: similar to hexokinase domain... 550 e-155
ref|NP_663394.1| hexokinase domain containing 1 [Mus muscul... 550 e-155
gb|AAH12337.1| HKDC1 protein [Homo sapiens] 550 e-155
emb|CAH71500.1| hexokinase domain containing 1 [Homo sapiens] 550 e-154
emb|CAA43855.1| hexakinase [Kluyveromyces lactis] 550 e-154
gb|AAP40021.1| hexokinase [Nicotiana benthamiana] 549 e-154
ref|XP_421579.2| PREDICTED: similar to Hexokinase domain co... 549 e-154
ref|XP_001525198.1| hexokinase [Lodderomyces elongisporus N... 549 e-154
gb|AAL93565.1|AF488830_1 hexokinase [Trypanosoma cruzi] >gi... 549 e-154
ref|NP_985826.1| AFR279Cp [Ashbya gossypii ATCC 10895] >gi|... 549 e-154
ref|XP_001381777.1| PREDICTED: similar to hexokinase II [Mo... 549 e-154
ref|XP_001660031.1| hexokinase [Aedes aegypti] >gi|10887452... 548 e-154
ref|XP_001400569.1| hexokinase hxk-Aspergillus niger >gi|41... 548 e-154
emb|CAH65327.1| hypothetical protein [Gallus gallus] 548 e-154
ref|XP_532991.2| PREDICTED: similar to hexokinase 2 [Canis ... 548 e-154
dbj|BAF83046.1| unnamed protein product [Homo sapiens] 548 e-154
gb|AAA41334.1| hexokinase type II 548 e-154
ref|XP_816463.1| hexokinase, putative [Trypanosoma cruzi st... 548 e-154
gb|AAY24209.1| unknown [Homo sapiens] 548 e-154
ref|NP_989543.1| hexokinase 2 [Gallus gallus] >gi|23821302|... 548 e-154
pdb|2NZT|A Chain A, Crystal Structure Of Human Hexokinase I... 548 e-154
ref|XP_822457.1| hexokinase [Trypanosoma brucei TREU927] >g... 548 e-154
ref|NP_001116459.1| hexokinase 2 [Sus scrofa] >gi|122134685... 548 e-154
ref|NP_038848.1| hexokinase 2 [Mus musculus] >gi|2495218|sp... 548 e-154
ref|XP_001110227.1| PREDICTED: similar to hexokinase 1 isof... 548 e-154
ref|NP_000180.2| hexokinase 2 [Homo sapiens] >gi|56405344|s... 548 e-154
ref|NP_001096201.1| hexokinase 1 [Xenopus tropicalis] >gi|1... 547 e-154
ref|XP_870563.2| PREDICTED: similar to hexokinase II [Bos t... 547 e-154
ref|NP_036867.1| hexokinase 2 [Rattus norvegicus] >gi|12389... 547 e-154
ref|XP_001850122.1| hexokinase [Culex pipiens quinquefascia... 547 e-154
dbj|BAE26802.1| unnamed protein product [Mus musculus] 547 e-154
gb|AAS60192.1| hexokinase 1a [Nicotiana tabacum] 547 e-154
ref|XP_001364147.1| PREDICTED: similar to Hexokinase domain... 547 e-154
sp|P17710|HXK1_MOUSE Hexokinase-1 (Hexokinase type I) (HK I... 547 e-154
ref|XP_546137.2| PREDICTED: similar to hexokinase domain co... 547 e-154
ref|XP_808992.1| hexokinase, putative [Trypanosoma cruzi st... 547 e-153
ref|NP_001096656.1| hexokinase I [Xenopus laevis] >gi|49114... 547 e-153
ref|NP_034568.1| hexokinase 1 [Mus musculus] >gi|1850140|gb... 547 e-153
ref|XP_001162535.1| PREDICTED: hexokinase 2 isoform 2 [Pan ... 547 e-153
gb|EDL92980.1| hexokinase 1, isoform CRA_a [Rattus norvegicus] 546 e-153
gb|EDL32103.1| hexokinase 1, isoform CRA_a [Mus musculus] 546 e-153
emb|CAA86511.1| Human hexokinase II cDNA [Homo sapiens] 546 e-153
ref|XP_001111706.1| PREDICTED: similar to hexokinase 2 isof... 546 e-153
ref|XP_001162408.1| PREDICTED: hexokinase 2 isoform 1 [Pan ... 546 e-153
gb|AAU05129.1| hexokinase [Aedes aegypti] 546 e-153
gb|EDL92983.1| hexokinase 1, isoform CRA_d [Rattus norvegicus] 546 e-153
gb|EDL92981.1| hexokinase 1, isoform CRA_b [Rattus norvegicus] 546 e-153
gb|EDL92987.1| hexokinase 1, isoform CRA_h [Rattus norvegicus] 545 e-153
gb|EDL92989.1| hexokinase 1, isoform CRA_j [Rattus norvegicus] 545 e-153
ref|XP_001110396.1| PREDICTED: similar to hexokinase 1 isof... 545 e-153
ref|XP_001111663.1| PREDICTED: similar to hexokinase 2 isof... 545 e-153
emb|CAC81350.1| hexokinase [Solanum lycopersicum] 545 e-153
gb|EDL92985.1| hexokinase 1, isoform CRA_f [Rattus norvegicus] 545 e-153
ref|XP_001110269.1| PREDICTED: similar to hexokinase 1 isof... 545 e-153
ref|XP_001110350.1| PREDICTED: similar to hexokinase 1 isof... 545 e-153
ref|XP_680728.1| hypothetical protein AN7459.2 [Aspergillus... 545 e-153
ref|NP_989432.1| hexokinase 1 [Gallus gallus] >gi|23821300|... 545 e-153
ref|NP_524848.1| Hexokinase A CG3001-PA, isoform A [Drosoph... 545 e-153
gb|EDL32105.1| hexokinase 1, isoform CRA_c [Mus musculus] 545 e-153
gb|EDL92982.1| hexokinase 1, isoform CRA_c [Rattus norvegicus] 545 e-153
gb|EDL32108.1| hexokinase 1, isoform CRA_f [Mus musculus] 544 e-153
gb|EDL92984.1| hexokinase 1, isoform CRA_e [Rattus norvegicus] 544 e-153
gb|EDL92988.1| hexokinase 1, isoform CRA_i [Rattus norvegicus] 544 e-153
gb|EDL92990.1| hexokinase 1, isoform CRA_k [Rattus norvegicus] 544 e-153
gb|EDL32107.1| hexokinase 1, isoform CRA_e [Mus musculus] 544 e-153
gb|EDL32104.1| hexokinase 1, isoform CRA_b [Mus musculus] 544 e-153
gb|EDL92986.1| hexokinase 1, isoform CRA_g [Rattus norvegicus] 544 e-153
gb|AAH72628.1| Hk1 protein [Mus musculus] >gi|148700159|gb|... 544 e-153
dbj|BAD92763.1| hexokinase 1 isoform HKI variant [Homo sapi... 543 e-153
gb|AAB91396.1| mutant type II hexokinase [Rattus norvegicus] 543 e-153
emb|CAH18060.1| hypothetical protein [Homo sapiens] 543 e-153
gb|AAG18422.1|AF288471_1 hexokinase I [Xenopus laevis] 543 e-153
gb|EAW54323.1| hexokinase 1, isoform CRA_d [Homo sapiens] 543 e-152
ref|NP_036866.1| hexokinase 1 [Rattus norvegicus] >gi|62266... 543 e-152
dbj|BAE36411.1| unnamed protein product [Mus musculus] 543 e-152
dbj|BAE25472.1| unnamed protein product [Mus musculus] 543 e-152
gb|AAA37804.1| hexokinase (EC 2.7.1.1) 543 e-152
sp|Q9SEK2|HXK1_TOBAC Hexokinase-1 (NtHxK1) >gi|6594674|gb|A... 543 e-152
ref|NP_592948.1| hexokinase 1 (PMID 8549830) [Schizosacchar... 543 e-152
dbj|BAE39552.1| unnamed protein product [Mus musculus] 542 e-152
gb|AAT77515.1| hexokinase 7 [Nicotiana tabacum] 542 e-152
ref|XP_001169215.1| PREDICTED: hexokinase 1 isoform 8 [Pan ... 542 e-152
sp|Q5RC71|HXK1_PONPY Hexokinase-1 (Hexokinase type I) (HK I... 542 e-152
pdb|1CZA|N Chain N, Mutant Monomer Of Recombinant Human Hex... 542 e-152
ref|NP_277031.1| hexokinase 1 isoform HKI-R [Homo sapiens] ... 542 e-152
gb|AAS60194.1| hexokinase 3 [Nicotiana tabacum] 542 e-152
ref|NP_000179.2| hexokinase 1 isoform HKI [Homo sapiens] >g... 542 e-152
gb|AAQ02439.1| hexokinase 1 [synthetic construct] 542 e-152
emb|CAA86476.2| hexokinase II [Homo sapiens] 542 e-152
ref|NP_277032.1| hexokinase 1 isoform HKI-ta/tb [Homo sapie... 542 e-152
ref|NP_277035.2| hexokinase 1 isoform HKI-td [Homo sapiens] 542 e-152
gb|AAF82320.1|AAF82320 hexokinase 1 isoform td [Homo sapien... 541 e-152
gb|AAG28503.1|AF196966_1 hexokinase [Citrus sinensis] 541 e-152
ref|NP_001075245.1| hexokinase II [Equus caballus] >gi|1463... 541 e-152
ref|XP_702631.1| PREDICTED: hypothetical protein [Danio rer... 541 e-152
ref|NP_998417.1| hexokinase 1 [Danio rerio] >gi|28856173|gb... 541 e-152
dbj|BAF84701.1| unnamed protein product [Homo sapiens] 540 e-152
ref|XP_507830.2| PREDICTED: hexokinase 1 isoform 10 [Pan tr... 540 e-152
ref|NP_727350.1| Hexokinase A CG3001-PB, isoform B [Drosoph... 540 e-152
ref|XP_001169044.1| PREDICTED: hexokinase 1 isoform 1 [Pan ... 540 e-152
ref|XP_001169069.1| PREDICTED: hexokinase 1 isoform 2 [Pan ... 540 e-152
pdb|1HKC|A Chain A, Recombinant Human Hexokinase Type I Com... 540 e-151
ref|XP_001169123.1| PREDICTED: hexokinase 1 isoform 4 [Pan ... 540 e-151
gb|ABA01010.1| hexokinase [Solanum chacoense] 540 e-151
gb|AAF28854.1| hexokinase I [Cyprinus carpio] 540 e-151
sp|Q9SQ76|HXK2_SOLTU Hexokinase-2 (StHK2) >gi|6492118|gb|AA... 540 e-151
gb|AAG35735.1|AF208543_1 hexokinase [Lycopersicon esculentum] 540 e-151
gb|AAT77513.1| hexokinase 3 [Nicotiana sylvestris] 539 e-151
ref|XP_001487588.1| hypothetical protein PGUG_00965 [Pichia... 539 e-151
emb|CAA47379.1| hexokinase type 1 [Homo sapiens] 539 e-151
pdb|1DGK|N Chain N, Mutant Monomer Of Recombinant Human Hex... 539 e-151
ref|NP_998231.1| hexokinase 2 [Danio rerio] >gi|28278945|gb... 539 e-151
gb|AAA52646.1| hexokinase 1 [Homo sapiens] 539 e-151
ref|XP_536376.2| PREDICTED: similar to Hexokinase, type I (... 539 e-151
emb|CAO65442.1| unnamed protein product [Vitis vinifera] 538 e-151
ref|NP_001012686.1| hexokinase 1 [Bos taurus] >gi|33332343|... 537 e-151
ref|XP_001355083.1| GA15574-PA [Drosophila pseudoobscura] >... 537 e-150
gb|ABS89272.1| hexokinase 1a [Gadus morhua] 536 e-150
ref|XP_001564741.1| hexokinase, putative [Leishmania brazil... 536 e-150
ref|NP_001108597.1| hexokinase domain containing 1 [Danio r... 536 e-150
emb|CAN83149.1| hypothetical protein [Vitis vinifera] 536 e-150
ref|XP_001333260.1| PREDICTED: similar to Hexokinase domain... 535 e-150
gb|AAU05128.1| hexokinase [Aedes albopictus] 535 e-150
sp|Q9SEK3|HXK1_SPIOL Hexokinase-1 (SoHxK1) >gi|6594672|gb|A... 534 e-150
gb|AAY60841.1| hexokinase [Solanum lycopersicum] 534 e-150
gb|AAL60584.1|AF454962_1 hexokinase [Brassica oleracea] 533 e-149
sp|P50506|HXK_DEBOC Hexokinase >gi|1041966|gb|AAB34892.1| h... 533 e-149
ref|NP_011261.1| Hexokinase isoenzyme 2 that catalyzes phos... 532 e-149
gb|AAS60197.1| hexokinase 5 [Nicotiana tabacum] 532 e-149
emb|CAF90567.1| unnamed protein product [Tetraodon nigrovir... 532 e-149
ref|NP_194642.1| ATHXK1 (GLUCOSE INSENSITIVE 2); ATP bindin... 531 e-149
gb|ABS89273.1| hexokinase 1b [Gadus morhua] 531 e-149
gb|AAS60195.1| hexokinase 4a [Nicotiana tabacum] 531 e-149
ref|XP_970645.1| PREDICTED: similar to CG3001-PA, isoform A... 530 e-149
ref|XP_546212.2| PREDICTED: similar to Hexokinase type III ... 530 e-148
gb|AAS60196.1| hexokinase 4b [Nicotiana tabacum] 530 e-148
ref|XP_001465336.1| hexokinase [Leishmania infantum JPCM5] ... 530 e-148
ref|NP_001120545.1| hypothetical protein LOC100145699 [Xeno... 528 e-148
gb|AAT72300.1| hemoglobin receptor [Leishmania donovani] 528 e-148
ref|XP_001498596.1| PREDICTED: similar to Hexokinase 3 (whi... 528 e-148
emb|CAA27203.1| unnamed protein product [Saccharomyces cere... 528 e-148
ref|XP_001465335.1| hexokinase [Leishmania infantum JPCM5] ... 527 e-148
ref|XP_518124.2| PREDICTED: hexokinase 3 isoform 2 [Pan tro... 527 e-148
ref|XP_444978.1| hypothetical protein CAGL0A04829g [Candida... 527 e-148
ref|NP_179576.1| ATHXK2 (HEXOKINASE 2); ATP binding / hexok... 527 e-148
gb|AAV91306.1| hexokinase A [Drosophila santomea] >gi|56428... 527 e-147
gb|AAH28129.1| Hexokinase 3 (white cell) [Homo sapiens] >gi... 527 e-147
gb|AAX43272.1| hexokinase 3 [synthetic construct] 527 e-147
ref|NP_776744.1| FK506 binding protein 12-rapamycin associa... 527 e-147
ref|NP_002106.1| hexokinase 3 [Homo sapiens] >gi|1708363|sp... 526 e-147
ref|NP_001090603.1| hypothetical protein LOC100036846 [Xeno... 526 e-147
gb|AAO24584.1| At2g19860 [Arabidopsis thaliana] >gi|1107436... 526 e-147
gb|AAH21278.1| HKDC1 protein [Homo sapiens] 525 e-147
ref|XP_001137121.1| PREDICTED: hexokinase 3 isoform 1 [Pan ... 525 e-147
ref|XP_001682958.1| hexokinase, putative [Leishmania major]... 525 e-147
ref|XP_001682957.1| hexokinase, putative [Leishmania major]... 525 e-147
ref|XP_001380610.1| PREDICTED: similar to hexokinase 1, [Mo... 525 e-147
ref|XP_001754148.1| hexokinase protein HXK7 [Physcomitrella... 524 e-147
ref|XP_001520120.1| PREDICTED: similar to glucokinase [Orni... 524 e-147
ref|XP_001255832.1| PREDICTED: similar to hexokinase II, pa... 524 e-147
ref|XP_759240.1| hypothetical protein UM03093.1 [Ustilago m... 524 e-147
ref|XP_001380968.1| PREDICTED: similar to Hexokinase 3 (whi... 523 e-146
gb|AAI00649.1| Hexokinase 3 [Rattus norvegicus] >gi|1490398... 523 e-146
ref|XP_001086179.1| PREDICTED: hexokinase 3 [Macaca mulatta] 523 e-146
emb|CAP36704.1| Hypothetical protein CBG19465 [Caenorhabdit... 522 e-146
gb|AAL60583.1|AF454961_1 hexokinase [Brassica oleracea] 521 e-146
emb|CAG09720.1| unnamed protein product [Tetraodon nigrovir... 521 e-146
emb|CAO45811.1| unnamed protein product [Vitis vinifera] 520 e-145
ref|XP_001752229.1| hexokinase protein HXK8 [Physcomitrella... 519 e-145
gb|EAW99603.1| hexokinase 2, isoform CRA_b [Homo sapiens] 519 e-145
ref|NP_071515.1| hexokinase 3 [Rattus norvegicus] >gi|12389... 519 e-145
dbj|BAE42341.1| unnamed protein product [Mus musculus] >gi|... 519 e-145
ref|XP_001265599.1| hexokinase [Neosartorya fischeri NRRL 1... 519 e-145
ref|XP_001643699.1| hypothetical protein Kpol_507p3 [Vander... 519 e-145
gb|EDL94016.1| hexokinase 3, isoform CRA_b [Rattus norvegicus] 519 e-145
ref|NP_001044214.1| Os01g0742500 [Oryza sativa (japonica cu... 518 e-145
ref|NP_001021106.1| F14B4.2a [Caenorhabditis elegans] >gi|3... 518 e-145
ref|NP_001028417.1| hexokinase 3 [Mus musculus] >gi|8328824... 518 e-145
dbj|BAE37000.1| unnamed protein product [Mus musculus] 518 e-145
dbj|BAE29220.1| unnamed protein product [Mus musculus] 518 e-145
gb|EDN59204.1| hexokinase I (PI) (also called hexokinase A)... 518 e-145
ref|NP_116711.1| Hexokinase isoenzyme 1, a cytosolic protei... 518 e-145
dbj|BAE42045.1| unnamed protein product [Mus musculus] 518 e-145
ref|XP_966410.1| PREDICTED: similar to CG3001-PA, isoform A... 517 e-145
emb|CAJ28915.1| hexokinase [Crassostrea gigas] 517 e-145
ref|NP_001021107.1| F14B4.2b [Caenorhabditis elegans] >gi|5... 517 e-144
dbj|BAE24390.1| unnamed protein product [Mus musculus] >gi|... 517 e-144
emb|CAA27202.1| unnamed protein product [Saccharomyces cere... 515 e-144
ref|XP_001784334.1| hexokinase protein HXK3 [Physcomitrella... 515 e-144
gb|AAI17861.1| Hk3 protein [Mus musculus] 515 e-144
gb|EAY75659.1| hypothetical protein OsI_003506 [Oryza sativ... 515 e-144
ref|XP_001878887.1| hexokinase [Laccaria bicolor S238N-H82]... 514 e-144
gb|AAI17862.1| Hk3 protein [Mus musculus] 514 e-144
dbj|BAE35470.1| unnamed protein product [Mus musculus] >gi|... 514 e-144
emb|CAG05684.1| unnamed protein product [Tetraodon nigrovir... 513 e-144
dbj|BAE29007.1| unnamed protein product [Mus musculus] 513 e-143
ref|XP_001379711.1| PREDICTED: similar to glucokinase [Mono... 512 e-143
gb|AAA34698.1| hexokinase (HXK1) 511 e-143
ref|XP_975828.1| PREDICTED: similar to CG3001-PA, isoform A... 510 e-143
gb|AAA60333.1| hexokinase [Arabidopsis thaliana] >gi|158238... 509 e-142
ref|XP_572328.1| hexokinase [Cryptococcus neoformans var. n... 509 e-142
ref|NP_001096321.1| hypothetical protein LOC100124905 [Xeno... 508 e-142
ref|XP_001899820.1| Hexokinase family protein [Brugia malay... 508 e-142
sp|Q2KNB7|HXK9_ORYSJ Hexokinase-9 (Hexokinase-5) >gi|621307... 508 e-142
gb|AAG22922.1|AF257605_2 hexokinase-t2 [Drosophila melanoga... 507 e-142
gb|EEH38094.1| hexokinase [Paracoccidioides brasiliensis Pb01] 507 e-142
ref|XP_001784630.1| hexokinase protein HXK2 [Physcomitrella... 507 e-141
gb|EEH47729.1| hexokinase [Paracoccidioides brasiliensis Pb18] 506 e-141
gb|AAG22924.1|AF257606_2 hexokinase-t2 [Drosophila melanoga... 506 e-141
gb|AAG22908.1|AF257598_2 hexokinase-t2 [Drosophila melanoga... 506 e-141
ref|XP_975717.1| PREDICTED: similar to CG3001-PA, isoform A... 505 e-141
gb|AAG22896.1|AF257592_2 hexokinase-t2 [Drosophila melanoga... 505 e-141
gb|AAG22892.1|AF257590_2 hexokinase-t2 [Drosophila melanoga... 505 e-141
gb|AAG22918.1|AF257603_2 hexokinase-t2 [Drosophila melanoga... 505 e-141
gb|AAV32455.1| hexokinase [Leishmania infantum] 505 e-141
ref|NP_001079298.1| glucokinase [Xenopus laevis] >gi|126284... 505 e-141
ref|XP_001837942.1| hypothetical protein CC1G_11986 [Coprin... 505 e-141
ref|XP_001360104.1| GA20820-PA [Drosophila pseudoobscura] >... 505 e-141
gb|EAY98804.1| hypothetical protein OsI_020037 [Oryza sativ... 504 e-141
sp|Q2KNB9|HXK2_ORYSJ Hexokinase-2 (Hexokinase-3) >gi|621307... 504 e-141
ref|XP_501216.1| hypothetical protein [Yarrowia lipolytica]... 504 e-141
ref|NP_733151.2| Hex-t2 CG32849-PA [Drosophila melanogaster... 503 e-140
ref|XP_001772444.1| hexokinase protein HXK1 [Physcomitrella... 503 e-140
gb|AAL13623.1| GH15883p [Drosophila melanogaster] 502 e-140
gb|AAG22928.1|AF257608_2 hexokinase-t2 [Drosophila melanoga... 501 e-140
emb|CAN74362.1| hypothetical protein [Vitis vinifera] 500 e-140
ref|NP_000153.1| glucokinase isoform 1 [Homo sapiens] >gi|5... 500 e-140
gb|AAP36837.1| Homo sapiens glucokinase (hexokinase 4, matu... 500 e-140
ref|XP_001143661.1| PREDICTED: glucokinase isoform 3 [Pan t... 500 e-140
ref|XP_717498.1| hexokinase II [Candida albicans SC5314] >g... 500 e-140
gb|AAG22944.1|AF257637_2 hexokinase-t2 [Drosophila simulans... 500 e-140
gb|AAG22956.1|AF257643_2 hexokinase-t2 [Drosophila simulans... 500 e-139
gb|AAQ72424.1| hexokinase PpHxk1 [Physcomitrella patens] >g... 500 e-139
gb|AAG21973.1|AF257652_2 hexokinase-t2 [Drosophila yakuba] 500 e-139
gb|ABS31137.1| glucokinase [Homo sapiens] 500 e-139
ref|XP_749181.1| hexokinase [Aspergillus fumigatus Af293] >... 499 e-139
ref|XP_447127.1| unnamed protein product [Candida glabrata]... 499 e-139
ref|XP_001220303.1| hypothetical protein CHGG_01082 [Chaeto... 498 e-139
gb|AAQ19647.1| hexokinase [Pichia angusta] 498 e-139
gb|AAG22954.1|AF257642_2 hexokinase-t2 [Drosophila simulans... 498 e-139
ref|XP_001762951.1| hexokinase protein HXK6 [Physcomitrella... 498 e-139
ref|XP_001898658.1| hexokinase [Brugia malayi] >gi|15859392... 498 e-139
gb|AAB59563.1| glucokinase 498 e-139
gb|AAV32456.1| hexokinase [Leishmania mexicana] 497 e-139
ref|NP_277043.1| glucokinase isoform 3 [Homo sapiens] >gi|2... 497 e-139
ref|XP_747854.1| glucokinase GlkA [Aspergillus fumigatus Af... 497 e-139
ref|NP_034422.2| glucokinase [Mus musculus] >gi|1708365|sp|... 497 e-139
ref|XP_001143302.1| PREDICTED: glucokinase isoform 1 [Pan t... 497 e-139
ref|XP_001093035.1| PREDICTED: similar to glucokinase isofo... 496 e-138
ref|NP_001095772.1| glucokinase [Bos taurus] >gi|151554675|... 496 e-138
gb|AAG23076.1|AF257552_1 hexokinase-C [Drosophila melanogas... 496 e-138
ref|NP_001077423.1| glucokinase [Felis catus] >gi|125434898... 496 e-138
sp|P17712|HXK4_RAT Glucokinase (Hexokinase-4) (Hexokinase t... 495 e-138
gb|AAC50422.1| ATP:D-hexose 6-phosphotransferase 495 e-138
gb|AAG23108.1|AF257584_1 hexokinase-C [Drosophila melanogas... 495 e-138
ref|NP_524674.1| Hexokinase C CG8094-PA [Drosophila melanog... 495 e-138
ref|XP_001766433.1| hexokinase protein HXK5 [Physcomitrella... 495 e-138
pdb|1V4T|A Chain A, Crystal Structure Of Human Glucokinase 495 e-138
gb|AAG22929.1|AF257623_1 hexokinase-C [Drosophila simulans]... 494 e-138
ref|XP_001092919.1| PREDICTED: similar to glucokinase isofo... 494 e-138
ref|NP_277042.1| glucokinase isoform 2 [Homo sapiens] >gi|2... 494 e-138
ref|XP_001143590.1| PREDICTED: glucokinase isoform 2 [Pan t... 494 e-138
pdb|1V4S|A Chain A, Crystal Structure Of Human Glucokinase 494 e-138
gb|AAG21971.1|AF257651_1 hexokinase-C [Drosophila yakuba] 494 e-138
gb|AAG23066.1|AF257542_1 hexokinase-C [Drosophila melanogas... 494 e-138
dbj|BAD92188.1| Hexokinase 3 variant [Homo sapiens] 494 e-138
ref|XP_001257412.1| glucokinase GlkA, putative [Neosartorya... 493 e-137
gb|AAG23068.1|AF257544_1 hexokinase-C [Drosophila melanogas... 493 e-137
gb|AAC33587.2| glucokinase [Cyprinus carpio] 493 e-137
ref|XP_681958.1| HXKG_ASPNG GLUCOKINASE (GLUCOSE KINASE) (G... 492 e-137
ref|XP_001605294.1| PREDICTED: similar to ENSANGP0000002836... 491 e-137
ref|XP_001732021.1| hypothetical protein MGL_1289 [Malassez... 491 e-137
Sequences not found previously or not previously below threshold:
>gb|AAY83348.1| hexokinase [Hypocrea jecorina]
Length = 492
Score = 576 bits (1485), Expect = e-162, Method: Composition-based stats.
Identities = 152/474 (32%), Positives = 236/474 (49%), Gaps = 16/474 (3%)
Query: 10 EHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRM 69
+ L FT+ +++I + + E+ +GL ++ M
Sbjct: 6 PRPPPSRKGSAADLPKDLLNEVRKLEEIFTVDTAKLKEITDHFVNELAKGLSVEGGSIPM 65
Query: 70 LPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKE-GAVVDSSTSAFKIPKYALEGNAT 128
P++V TG F ALD+GGTN RV + + + D S +++P+ G++
Sbjct: 66 NPTWVMSYPDGHETGSFLALDMGGTNLRVCEITLTDRKSEFDIIQSKYRMPEELKTGSSE 125
Query: 129 DLFGFIASNVKKTMETRAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQ 187
+L+ +IA + + +ET + +PLGFTFS+P Q ++ G+L RWTKGF GV+
Sbjct: 126 ELWEYIADCLHQFIETHHGDCSKLEALPLGFTFSYPATQHYIDEGILQRWTKGFDIAGVE 185
Query: 188 GNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETA 247
G +V+ + +AA + + + + AL NDT GTLI+ + DP+V++G I GTG NA Y E
Sbjct: 186 GKNVVPMFEAAIAKRGVPIKLSALINDTTGTLIASAYTDPKVKIGCIFGTGCNAAYMEDC 245
Query: 248 SAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMIS 307
++ K + IN E G FD++++ VLP TK+D+ ID+ S GQQA EKMI+
Sbjct: 246 GSIPKLAHMNLPPDCPMAINCEWGAFDNEHK-VLPRTKYDIAIDEDSPRPGQQAFEKMIA 304
Query: 308 GMYLGEIARRVIVHLSSIN---CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRST 364
G+YLGEI R V+V L + L + +S F I D LQ T T
Sbjct: 305 GLYLGEIFRLVLVDLHDNKDIHIFENQDISLLRRPYTLDSSFLSGIEEDPFENLQETFDT 364
Query: 365 IQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFE 424
Q + + +L ++R + L+ RAA+LSA A K ++ + DGSVF
Sbjct: 365 FQSKLNI-TPTGPELELVRRLSELIGTRAARLSACGVAAI-CKKKSFESCHVGADGSVFN 422
Query: 425 KIPSFRRVLQDNINRILGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
K P F+ + IL E V + A+DGSG+GAA I+A+ +
Sbjct: 423 KYPHFKARGAKALREILDWPAKSNPKEEDPVEILAAEDGSGVGAALIAALTLKR 476
>ref|XP_749720.1| hexokinase Kxk [Aspergillus fumigatus Af293]
gb|EAL87682.1| hexokinase Kxk, putative [Aspergillus fumigatus Af293]
gb|EDP54242.1| hexokinase Kxk, putative [Aspergillus fumigatus A1163]
Length = 490
Score = 574 bits (1481), Expect = e-162, Method: Composition-based stats.
Identities = 150/464 (32%), Positives = 235/464 (50%), Gaps = 13/464 (2%)
Query: 17 NDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V +++ + FT+ ++Q++ + + E+ +GL + M ++V
Sbjct: 11 SRKGSMADVPQNLLQQIKDFEEMFTVDKAKLKQVVDHFVKELDKGLSVEGGNIPMNVTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
G F ALD+GGTN RV + +E D S +++P+ G A +L+ +
Sbjct: 71 MGFPDGDEQGTFLALDMGGTNLRVCEITLTEEKGGFDICQSKYRMPEELKTGTAEELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ +E E+ ++PLGFTFS+P Q ++ G+L RWTKGF GV+G DV+
Sbjct: 131 IADCIQQFIEFHHGEEGLTSLPLGFTFSYPATQEYIDHGILQRWTKGFDIDGVEGQDVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
L+ R L + V AL NDT GTLI+ + DPE+++G I GTG NA Y E +V K
Sbjct: 191 PLEETLKRKGLPIKVAALINDTTGTLIASAYTDPEMKIGCIFGTGVNAAYMENVGSVPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
+ IN E G FD+++ VLP TK+D ID S GQQA EKM +G+YLGE
Sbjct: 251 AHMNLPPDMPVAINCEYGAFDNEH-VVLPLTKYDHIIDRDSPRPGQQAFEKMTAGLYLGE 309
Query: 314 IARRVIVHLSSI--NCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
I R ++ L + + L ++ F I D LQ T+ ++
Sbjct: 310 IFRLALIDLLDSRPGLIFQNQDTSKLRKPYLLDASFLAAIEEDPYENLQETQELFERELN 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ ++ +L +IR + L+ RAA+LSA A K + + DGSVF K P F+
Sbjct: 370 IK-PTLAELEMIRRLAELIGTRAARLSACGVAAI-CKKKNIESCHVGADGSVFTKYPHFK 427
Query: 431 RVLQDNINRILGP----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ IL + V + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAQALREILDWAPNEKDKVTIMAAEDGSGVGAALIAALTLKR 471
>ref|XP_001260212.1| hexokinase Kxk, putative [Neosartorya fischeri NRRL 181]
gb|EAW18315.1| hexokinase Kxk, putative [Neosartorya fischeri NRRL 181]
Length = 490
Score = 574 bits (1480), Expect = e-162, Method: Composition-based stats.
Identities = 151/464 (32%), Positives = 235/464 (50%), Gaps = 13/464 (2%)
Query: 17 NDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V +++ + FT+ ++Q++ + + E+ +GL + M ++V
Sbjct: 11 SRKGSMADVPQNLLQQIKDFEEMFTVDRAKLKQVVDHFVKELEKGLSVEGGNIPMNVTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
G F ALD+GGTN RV + +E D S +++P+ G A +L+ +
Sbjct: 71 MDFPDGDEQGTFLALDMGGTNLRVCEITLTEEKGGFDICQSKYRMPEELKSGTAEELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ +E E+ ++PLGFTFS+P Q ++ GVL RWTKGF GV+G DV+
Sbjct: 131 IADCIQQFIEFHHGEEGLTSLPLGFTFSYPATQEYIDHGVLQRWTKGFDIDGVEGQDVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
L+ R L + V AL NDT GTLI+ + DPE+++G I GTG NA Y E +V K
Sbjct: 191 PLEETLKRKGLPIKVAALINDTTGTLIASAYTDPEMKIGCIFGTGVNAAYMEDVGSVPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
+ IN E G FD+++ VLP TK+D ID S GQQA EKM +G+YLGE
Sbjct: 251 AHMNLPPDMPVAINCEYGAFDNEH-VVLPLTKYDHIIDRDSPRPGQQAFEKMTAGLYLGE 309
Query: 314 IARRVIVHLSSI--NCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
I R ++ L + + L ++ F I D LQ T+ ++
Sbjct: 310 IFRLALIDLLDSRPGLIFQNQDTSKLRKPYLLDASFLAAIEEDPYENLQETQELFERELN 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ ++ +L +IR + L+ RAA+LSA A K + + DGSVF K P F+
Sbjct: 370 IK-PTLAELEMIRRLAELIGTRAARLSACGVAAI-CKKKNIESCHVGADGSVFTKYPHFK 427
Query: 431 RVLQDNINRILGP----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ IL + V + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAQALREILDWAPNEKDKVTIMAAEDGSGVGAALIAALTLKR 471
>ref|XP_380676.1| hypothetical protein FG00500.1 [Gibberella zeae PH-1]
Length = 572
Score = 574 bits (1480), Expect = e-162, Method: Composition-based stats.
Identities = 149/470 (31%), Positives = 234/470 (49%), Gaps = 18/470 (3%)
Query: 16 GNDGETVRAVKRDVA--MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSY 73
G+ ++ V +D+A + L N FT+ +++I + + E+ +GL ++ M P++
Sbjct: 90 GSQRGSMADVPKDLAEEINKLENLFTVQPSKLKEITNHFVSELAKGLSVEGGSIPMNPTW 149
Query: 74 VYKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFG 132
V TG + ALD+GGTN RV ++ E + D S +++P+ G + +L+
Sbjct: 150 VMSYPDGYETGTYLALDMGGTNLRVCQITLTDEKSEFDIIQSKYRMPEELKSGTSEELWE 209
Query: 133 FIASNVKKTMETRAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDV 191
+IA + + +ET + +PLGFTFS+P Q ++ G+L RWTKGF GV+G ++
Sbjct: 210 YIAECLYQFLETHHGDCTKLEKIPLGFTFSYPATQNYIDEGILQRWTKGFDIDGVEGQNI 269
Query: 192 IALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVT 251
+ + + A + + + A+ NDT GTLI+ + D +++G I GTG NA Y E ++
Sbjct: 270 VPMFEEALKTRGVPIKLAAIINDTTGTLIASAYTDTAMKIGCIFGTGCNAAYMEDCGSIP 329
Query: 252 KDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYL 311
K + IN E G FD++++ VLP T +D+ ID S GQQA EKMI+G+YL
Sbjct: 330 KIADLNLPADLPMAINCEWGAFDNEHK-VLPRTPYDVIIDKESPRPGQQAFEKMIAGLYL 388
Query: 312 GEIARRVIVHLSSIN---CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKV 368
GEI R ++V L L S ++ F I D L T K
Sbjct: 389 GEIFRLILVDLHDNKSIHIFENQDIALLRKPYSLDASFLSAIEEDPWENLSETSDLFSKK 448
Query: 369 CGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPS 428
+ E L +IR L+ RAA+LSA A K + + DGSVF K P
Sbjct: 449 LNLKCTQPE-LELIRRTAELIGTRAARLSACGVAAI-CKKKNYQSCHVGADGSVFNKYPH 506
Query: 429 FRRVLQDNINRILGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
F+ + IL E + + A+DGSG+GAA I+A+ +
Sbjct: 507 FKERGAKALRDILDWPEKTNKKEEDPIEVLTAEDGSGVGAALIAALTLKR 556
>ref|XP_965673.2| hexokinase [Neurospora crassa OR74A]
gb|EAA36437.2| hexokinase [Neurospora crassa OR74A]
Length = 489
Score = 573 bits (1478), Expect = e-161, Method: Composition-based stats.
Identities = 150/458 (32%), Positives = 237/458 (51%), Gaps = 16/458 (3%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGV 85
+ L FT+ ++++ + ++E+ +GL + ++ M P++V TG
Sbjct: 12 DLRNEIEHLERLFTVDGAKLKEVTNHFVHELEKGLSVQGGSIPMNPTWVMSFPDGNETGT 71
Query: 86 FYALDLGGTNFRVLRVACKE-GAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMET 144
+ ALD+GGTN RV +V E + D S +++P+ G+A +L+ +IA + + +ET
Sbjct: 72 YLALDMGGTNLRVCQVTLTETKSEFDIIQSKYRMPEELKTGDAEELWEYIADCLMQFIET 131
Query: 145 RAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS 203
+ +PLGFTFS+P Q ++ G+L RWTKGF GV+G++V+ + +AA R
Sbjct: 132 HHGDPTKLDALPLGFTFSYPATQNYIDEGILQRWTKGFDIAGVEGHNVVPMFEAALQRRG 191
Query: 204 LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSAL 263
+ + + AL NDT GTLI+ + DP++++G I GTG NA Y E ++ K +
Sbjct: 192 VPIKLTALINDTTGTLIASAYTDPKMRIGCIFGTGCNAAYMENCGSIPKLAHMNLPPDMP 251
Query: 264 TPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLS 323
IN E G FD++++ VLP T +D+ ID S GQQ+ EKM++G+YLGEI R V+V L
Sbjct: 252 MAINCEWGAFDNEHK-VLPRTPYDVIIDKDSPRPGQQSFEKMVAGLYLGEIFRLVLVDLH 310
Query: 324 SI---NCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLR 380
P L S +S F +I D L T Q G+ + +L
Sbjct: 311 DNQEIKIFPGQDIAKLRKAYSLDSSFLSLIEEDPFENLSETFELFQTKLGL-TPTGPELE 369
Query: 381 IIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRI 440
+IR L+ RAA+LSA A K + + DGSVF K P+F+ + I
Sbjct: 370 LIRRTAELIGTRAARLSACGVAAISKKKG-YKQCHVGADGSVFNKYPNFKARGAQALREI 428
Query: 441 LGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
L + + + A+DGSG+GAA I+A+ +
Sbjct: 429 LDWPEKADPKEDDPIEILAAEDGSGVGAALIAALTMQR 466
>ref|XP_001912895.1| unnamed protein product [Podospora anserina]
emb|CAP60377.1| unnamed protein product [Podospora anserina]
Length = 482
Score = 572 bits (1476), Expect = e-161, Method: Composition-based stats.
Identities = 153/470 (32%), Positives = 232/470 (49%), Gaps = 18/470 (3%)
Query: 14 IQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSY 73
G+ E + + L FT+ ++QI + + E+ +GL T+ M P++
Sbjct: 2 SSGSFVEVPK--DLLKEIKRLEELFTVDTAKLKQITDHFVNELEKGLSKEGGTIPMNPTW 59
Query: 74 VYKADPKRATGVFYALDLGGTNFRVLRVACKE-GAVVDSSTSAFKIPKYALEGNATDLFG 132
V TG + ALD+GGTN RV ++ E + D S +++P+ G A DL+
Sbjct: 60 VMSFPTGYETGTYLALDMGGTNLRVCQITLTEQKSEFDIIQSKYRMPEELKTGVAEDLWE 119
Query: 133 FIASNVKKTMETRAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDV 191
+IA + + ++T + +PLGFTFS+P Q ++ G+L RWTKGF GV+G +V
Sbjct: 120 YIAECLLQFIQTHHGDVAKLDKLPLGFTFSYPATQNYIDEGILQRWTKGFDIDGVEGRNV 179
Query: 192 IALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVT 251
+ + + A + + + AL NDT GTLI+ + D ++++G I GTG NA Y E ++
Sbjct: 180 VPMFEKALQERGVPIKLTALINDTTGTLIASAYTDTKMKIGCIFGTGCNAAYMEDCGSIP 239
Query: 252 KDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYL 311
K + IN E G FD++ + VLP T +D ID S GQQA EKMI+G+YL
Sbjct: 240 KLAHLNLPPDTPMAINCEWGAFDNELK-VLPRTPYDESIDTDSPRPGQQAFEKMIAGLYL 298
Query: 312 GEIARRVIVHLSSI---NCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKV 368
GEI R ++V L N L + +S F I D L TR Q
Sbjct: 299 GEIFRLIMVDLHDNHNVNIFAGQDIGKLRRPYTLDSSFLSAIEDDPFENLSETRELFQNQ 358
Query: 369 CGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPS 428
G+D + +L +IR L+ RAA+LSA A K + DGSVF K P
Sbjct: 359 LGID-PNPSELELIRRAAELIGTRAARLSACGVAAISKKKG-YKECHVGADGSVFNKYPH 416
Query: 429 FRRVLQDNINRILGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
F++ + IL + + + A+DGSG+GAA I+A+ +
Sbjct: 417 FKKRGAAALREILDWPAKADPNDDDPIEILAAEDGSGVGAALIAALTLER 466
>ref|XP_001597079.1| hypothetical protein SS1G_01273 [Sclerotinia sclerotiorum 1980]
gb|EDN96347.1| hypothetical protein SS1G_01273 [Sclerotinia sclerotiorum 1980]
Length = 491
Score = 572 bits (1475), Expect = e-161, Method: Composition-based stats.
Identities = 147/468 (31%), Positives = 238/468 (50%), Gaps = 17/468 (3%)
Query: 17 NDGETVRAVKRD--VAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V ++ + L QFT+ + +++I + + E+ +GL ++ M P++
Sbjct: 11 SRKGSMAEVPKNFLEQIKKLEQQFTVDTKKLKEITEHFVSELTKGLTVEGGSIPMNPTWC 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
TG F ALD+GGTN RV + E + D S +++P+ G+A +L+ +
Sbjct: 71 MSFPDGYETGTFLALDMGGTNLRVCEIILTDEKSEFDIMQSKYRMPEELKTGDADELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ +E+ + + LGFTFS+P Q ++ G+L RWTKGF +GV+G +V+
Sbjct: 131 IADCLQQFIESHHQGEKLDKLSLGFTFSYPATQNYIDEGILQRWTKGFDIEGVEGENVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
+ +AA + + + + AL NDT GTLI+ + D +++G I GTG NA Y E ++ K
Sbjct: 191 MFEAALAKRGVPIKLTALINDTTGTLIASAYTDTSMKIGCIFGTGCNAAYMENCGSIPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
+ IN E G FD++++ VLP T +D+ ID S GQQA EKMI+G+YLGE
Sbjct: 251 AHMNLPPDTPMAINCEWGAFDNEHK-VLPRTPYDIIIDKDSPRPGQQAFEKMIAGLYLGE 309
Query: 314 IARRVIVHLSSIN---CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
+ R V+V L L + +S F ++ D L T Q G
Sbjct: 310 LFRLVLVDLHDNKDIHIFEGQDIEKLRKAYTLDSSFLSLVEEDPFENLSETADLFQNKLG 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ V ++ +L +IR + L+ RAA+LSA A K + DGSVF K P F+
Sbjct: 370 I-VTTVPELELIRRLAELIGTRAARLSACGVAAIAKKKG-YETCHVGADGSVFNKYPHFK 427
Query: 431 RVLQDNINRILGPECD--------VRAVLAKDGSGIGAAFISAMVVND 470
+ IL + + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAAALREILDWPAKKSPKEHDPIEILAAEDGSGVGAALIAALTLKR 475
>gb|ABY89285.1| putative hexokinase HXK1 [Gibberella moniliformis]
Length = 492
Score = 572 bits (1474), Expect = e-161, Method: Composition-based stats.
Identities = 145/476 (30%), Positives = 234/476 (49%), Gaps = 20/476 (4%)
Query: 10 EHISIQGNDGETVRAVKRDVA--MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTV 67
++ V +D+A + L FT+ +++I + + E+ +GL ++
Sbjct: 6 PRRPPSRKG--SMADVPKDLADEIHKLEKLFTVEPAKLKEITDHFVSELAKGLSVEGGSI 63
Query: 68 RMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGN 126
M P++V TG + ALD+GGTN RV ++ +E + D S +++P+ G
Sbjct: 64 PMNPTWVMSYPDGYETGTYLALDMGGTNLRVCQITLTEEKSEFDILQSKYRMPEELKSGT 123
Query: 127 ATDLFGFIASNVKKTMETRAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKG 185
+ +L+ +IA + + +ET + +PLGFTFS+P Q ++ G+L RWTKGF G
Sbjct: 124 SEELWEYIAECLYQFLETHHGDCSKLEKIPLGFTFSYPATQNYIDEGILQRWTKGFDIDG 183
Query: 186 VQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFE 245
V+G +++ + + A + + + A+ NDT GTLI+ + D +++G I GTG NA Y E
Sbjct: 184 VEGKNIVPMFEEALKARGVPIKLAAIINDTTGTLIASAYTDTAMKIGCIFGTGCNAAYME 243
Query: 246 TASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKM 305
++ K + IN E G FD++++ VLP T +D+ ID S GQQA EKM
Sbjct: 244 DCGSIPKIADLNLPADLPMAINCEWGAFDNEHK-VLPRTAYDVTIDKESPRPGQQAFEKM 302
Query: 306 ISGMYLGEIARRVIVHLSSIN---CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTR 362
I+G+YLGEI R ++V L + L S ++ F I D L T
Sbjct: 303 IAGLYLGEIFRLILVDLHDNKAIHIFENQDISLLRKPYSLDASFLSAIEEDPWENLTETY 362
Query: 363 STIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSV 422
K + + +L ++R L+ RAA+LSA A K + + DGSV
Sbjct: 363 DLFVKKLNLK-PTRPELELVRRTAELIGTRAARLSACGVAAI-CKKKGYESCHVGADGSV 420
Query: 423 FEKIPSFRRVLQDNINRILGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
F K P F+ + IL E + + A+DGSG+GAA I+A+ +
Sbjct: 421 FNKYPYFKERGAQALREILDWPEKTDKKAEDPIEVLTAEDGSGVGAALIAALTLKR 476
>ref|XP_001549109.1| hexokinase [Botryotinia fuckeliana B05.10]
gb|ABM30191.1| hexokinase [Botryotinia fuckeliana]
gb|EDN33783.1| hexokinase [Botryotinia fuckeliana B05.10]
Length = 491
Score = 569 bits (1468), Expect = e-160, Method: Composition-based stats.
Identities = 145/468 (30%), Positives = 236/468 (50%), Gaps = 17/468 (3%)
Query: 17 NDGETVRAVKRD--VAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V ++ + L QFT+ + +++I + + E+ +GL ++ M P++
Sbjct: 11 SRKGSMADVPKNYLEQIKKLEQQFTVDTQKLKEITEHFVSELTKGLTVEGGSIPMNPTWC 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
TG F ALD+GGTN RV + E + D S +++P+ G A +L+ +
Sbjct: 71 MAFPDGYETGTFLALDMGGTNLRVCEIILTDEKSEFDIIQSKYRMPEELKTGEADELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ +E+ + T+ LGFTFS+P Q ++ G+L RWTKGF GV+G +++
Sbjct: 131 IADCLQQFIESHHHGEDLGTLSLGFTFSYPATQNYIDEGILQRWTKGFDIAGVEGENIVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
+ +AA + + + + AL NDT GTLI+ + D +++G I GTG NA Y E ++ K
Sbjct: 191 MFEAALAKRGVPIKLTALINDTTGTLIASAYTDTAMKIGCIFGTGCNAAYMENCGSIPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
+ IN E G FD++++ VLP T +D+ ID S GQQA EKMI+G+YLGE
Sbjct: 251 AHMNLPPDTPMAINCEWGAFDNEHK-VLPRTPYDIIIDKDSPRPGQQAFEKMIAGLYLGE 309
Query: 314 IARRVIVHLSSINCLP---AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
+ R V+V L + L + +S F ++ D L T Q
Sbjct: 310 LFRLVLVDLHDNKDIHMFEGQDIEKLRKAYTLDSSFLSLVEEDPWENLSETADLFQNKLS 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ ++ +L +IR + L+ RAA+LSA A K + DGSVF K P F+
Sbjct: 370 IRA-TVPELELIRRLAELIGTRAARLSACGVAAIAKKK-NYETCHVGADGSVFNKYPHFK 427
Query: 431 RVLQDNINRILGPECD--------VRAVLAKDGSGIGAAFISAMVVND 470
+ IL + + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAAALREILDWPAKKNAKEADPIEILAAEDGSGVGAALIAALTLKR 475
>ref|XP_001247226.1| hexokinase [Coccidioides immitis RS]
gb|EAS35643.1| hexokinase [Coccidioides immitis RS]
Length = 490
Score = 568 bits (1465), Expect = e-160, Method: Composition-based stats.
Identities = 161/472 (34%), Positives = 238/472 (50%), Gaps = 15/472 (3%)
Query: 9 LEHISIQGNDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGREST 66
++ + +D+ + L FT+ +++I+ + + E+ +GL +
Sbjct: 5 APRRRPSRKG--SMADMPKDLLEQVKELEELFTVDQARLKKIVDHFVKELEKGLSVQGGN 62
Query: 67 VRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEG 125
+ M ++V G F ALD+GGTN RV + ++ D + S ++IP+ G
Sbjct: 63 IPMNVTWVMGFPTGHEHGTFLALDMGGTNLRVCEIFLCEKKGEFDITQSKYRIPEELKSG 122
Query: 126 NATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKG 185
NA DL+ +IA V++ +E E+ +PLGFTFS+P Q ++ GVL RWTKGF G
Sbjct: 123 NADDLWEYIADCVQQFIEYHHEEENLPDLPLGFTFSYPATQEYIDHGVLQRWTKGFDIDG 182
Query: 186 VQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFE 245
V+G DV+ +L+AA + L + V AL NDT GTLI+ + DPE+++G I GTG NA Y E
Sbjct: 183 VEGEDVVPMLEAALAKRGLPIKVAALINDTTGTLIASAYTDPEMRIGCIFGTGVNAAYME 242
Query: 246 TASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKM 305
A ++ K IN E G FD++ R VLP T++D+ ID S GQQA EKM
Sbjct: 243 NAGSIPKIAHYNLPPDMPIAINCEYGAFDNE-RVVLPLTQYDVVIDRDSPRPGQQAFEKM 301
Query: 306 ISGMYLGEIARRVIVHLSSIN---CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTR 362
+G+YLGEI R V++ L ++L +S F I D L TR
Sbjct: 302 TAGLYLGEIFRLVLLDLIDNKGNLIFEGQDVSSLRKPYCLDSSFLAYIEEDPFENLSETR 361
Query: 363 STIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSV 422
++ G+ E L + R + LV RAA+LSA A K + + DGSV
Sbjct: 362 DLFERTLGIKATKPE-LELCRRLAELVGTRAARLSACGVAAI-CKKKNIKSCHVGADGSV 419
Query: 423 FEKIPSFRRVLQDNINRILGP----ECDVRAVLAKDGSGIGAAFISAMVVND 470
F K P F+ + IL E V A+DGSG+GAA I+A+ +
Sbjct: 420 FNKYPHFKARGAKALREILDWADDEEDKVIICSAEDGSGVGAALIAALTLER 471
>ref|XP_364444.1| hexokinase [Magnaporthe grisea 70-15]
gb|EDJ97892.1| hexokinase [Magnaporthe grisea 70-15]
Length = 477
Score = 568 bits (1464), Expect = e-160, Method: Composition-based stats.
Identities = 151/458 (32%), Positives = 228/458 (49%), Gaps = 16/458 (3%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGV 85
+ L FT+ ++QI + + E+ GL + M P++V TG
Sbjct: 7 DLVKEIKDLEEMFTVDTAKLKQITNHFVGELERGLSVEGGDIPMNPTWVMSFPDGYETGT 66
Query: 86 FYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMET 144
F ALD+GGTN RV + + + D S +++P+ G + +L+ +IA + + +ET
Sbjct: 67 FLALDMGGTNLRVCEITLTDQKSEFDIIQSKYRMPEELKTGQSDELWDYIADCLLQFIET 126
Query: 145 RAPEDLN-RTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS 203
+ +PLGFTFS+P Q V+ G+L RWTKGF GV+G +V +L A
Sbjct: 127 HHGDPKKIEKLPLGFTFSYPATQNYVDEGILQRWTKGFDIAGVEGKNVAPMLMKALSERG 186
Query: 204 LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSAL 263
+ V +VAL NDT GTLI+ + D ++++G I GTG NA Y E ++ K +
Sbjct: 187 VPVKLVALINDTTGTLIASAYTDTQMRIGCIFGTGCNAAYMEECGSIPKLAHMNLPPETP 246
Query: 264 TPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLS 323
IN E G FD++++ VLP T +D+ ID+ S GQQA EKMI+G+YLGEI R ++V L
Sbjct: 247 MAINCEWGAFDNQHK-VLPRTPYDVKIDEDSPRPGQQAFEKMIAGLYLGEIFRLILVDLH 305
Query: 324 SI---NCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLR 380
+ L + +S F I D L T Q + V + +L
Sbjct: 306 DNHEVRIFKNQDISKLRRAYTLDSSFLSAIEDDPWENLSETLDLFQDKLNL-VPNRNELE 364
Query: 381 IIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRI 440
+IR L+ RAA+LSA A K + + DGSVF K P+F++ + I
Sbjct: 365 LIRRTAELIGTRAARLSACGVAAI-CKKKNYRSCHVGADGSVFNKYPNFKQRGAQALREI 423
Query: 441 LGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
L E + + A+DGSG+GAA I+A+ +
Sbjct: 424 LDWPAKEDPKEEDPIEILAAEDGSGVGAALIAALTLKR 461
>ref|XP_001275241.1| hexokinase Kxk, putative [Aspergillus clavatus NRRL 1]
gb|EAW13815.1| hexokinase Kxk, putative [Aspergillus clavatus NRRL 1]
Length = 490
Score = 567 bits (1463), Expect = e-160, Method: Composition-based stats.
Identities = 149/464 (32%), Positives = 236/464 (50%), Gaps = 13/464 (2%)
Query: 17 NDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V +++ + + FT+ ++Q++ + + E+ +GL + M ++V
Sbjct: 11 SRKGSMADVPQNLLQQIKEFEDMFTVDRTKLKQVVDHFVKELEQGLTVEGGNIPMNVTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
G F ALD+GGTN RV + +E D S +++P+ G A +L+ +
Sbjct: 71 MGFPDGDEQGTFLALDMGGTNLRVCEITLTEEKGAFDICQSKYRMPEELKTGTAEELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ ++ ++ +PLGFTFS+P Q ++ GVL RWTKGF GV+G DV+
Sbjct: 131 IADCLQQFIDFHHEDEELSQLPLGFTFSYPATQDYIDHGVLQRWTKGFDIDGVEGQDVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
L+A + L + V AL NDT GTLI+ + DPE+++G I GTG NA Y + +V K
Sbjct: 191 PLEAILQKKGLPIKVAALINDTTGTLIASAYTDPEMKIGCIFGTGVNAAYMDNVGSVPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
+ IN E G FD+++ VLP TK+D ID S GQQA EKM +G+YLGE
Sbjct: 251 AHMNLPPDMPVAINCEYGAFDNEH-IVLPLTKYDHIIDRDSPRPGQQAFEKMTAGLYLGE 309
Query: 314 IARRVIVHLSSI--NCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
I R ++ L + + L ++ F I D L+ T+ Q+
Sbjct: 310 IFRLALIDLLDSRPGLIFEGQDTSKLRKPYLLDASFLAAIEEDPYENLEETQELFQRELN 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ + +L +IR + L+ RAA+LSA A K + R + DGSVF K P+F+
Sbjct: 370 IK-PTQAELEMIRRLAELIGTRAARLSACGVAAI-CKKKNIERCHVGADGSVFTKYPNFK 427
Query: 431 RVLQDNINRILGP----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ IL V + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAQALREILDWAPNENDKVSILAAEDGSGVGAALIAALTLKR 471
>ref|XP_001819202.1| hypothetical protein [Aspergillus oryzae RIB40]
dbj|BAB12228.1| hexokinase [Aspergillus oryzae]
dbj|BAE57200.1| unnamed protein product [Aspergillus oryzae]
Length = 490
Score = 563 bits (1452), Expect = e-158, Method: Composition-based stats.
Identities = 149/464 (32%), Positives = 234/464 (50%), Gaps = 13/464 (2%)
Query: 17 NDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ + +++ + + FT+ ++QI + + E+ +GL + M ++V
Sbjct: 11 SRKGSMHELPQNLLEQIKQFEDIFTVDGAKLKQIADHFVKELEKGLSVEGGNIPMNVTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
G F ALD+GGTN RV + +E D + S +++P+ G A +L+ +
Sbjct: 71 MGFPDGDEQGTFLALDMGGTNLRVCEITLTEEKGAFDITQSKYRMPEELKTGTAEELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ +E+ + +PLGFTFS+P Q ++ GVL RWTKGF GV+G DV+
Sbjct: 131 IADCLQQFIESHHENEKLSKLPLGFTFSYPATQEYIDHGVLQRWTKGFDIDGVEGQDVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
L+A + L + V AL NDT GTLI+ + D ++++G I GTG NA Y E +V K
Sbjct: 191 PLEAILKKRGLPIKVAALINDTTGTLIASSYTDSDMKIGCIFGTGVNAAYMEHCGSVPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
IN E G FD+++ VLP TK+D+ ID S GQQA EKM +G+YLGE
Sbjct: 251 AHKNLPPDMPVAINCEYGAFDNEH-VVLPLTKYDIIIDRDSPRPGQQAFEKMTAGLYLGE 309
Query: 314 IARRVIVHLSSI--NCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
I R ++ L + + L ++ F I D LQ T+ +++
Sbjct: 310 IFRLALLDLLETRPGLIFQGQDTSQLRKPYLLDASFLAAIEDDPYENLQETQELMERKLN 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ E L +IR + L+ RAA+LSA A K + + DGSVF K P F+
Sbjct: 370 IKATQQE-LEMIRRLAELIGTRAARLSACGVAAI-CKKKNIESCHVGADGSVFTKYPHFK 427
Query: 431 RVLQDNINRILGP----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ IL + V + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAQALREILDWAPNEKDKVVIMAAEDGSGVGAALIAALTLKR 471
>ref|XP_001386689.2| Hexokinase [Pichia stipitis CBS 6054]
gb|ABN68660.2| Hexokinase [Pichia stipitis CBS 6054]
Length = 482
Score = 561 bits (1446), Expect = e-158, Method: Composition-based stats.
Identities = 157/462 (33%), Positives = 235/462 (50%), Gaps = 12/462 (2%)
Query: 18 DGETVRAVKRD--VAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVY 75
++ V + L + F +S E++R+I + + E+ +GL + + M+P +V
Sbjct: 12 RKGSLHDVPEALLKELEQLESVFNVSAETLRKITDHFVLELEKGLSKKGGNIPMIPGWVL 71
Query: 76 KADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIA 135
+ TG + A+DLGGTN RV+ V D++ S + +P + +L+ FIA
Sbjct: 72 DFPTGKETGDYLAIDLGGTNLRVVLVKLGGNRDFDTTQSKYPLPATMRTAKSEELWDFIA 131
Query: 136 SNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALL 195
+KK +E PE + +PLGFTFS+P Q+ +N G L RWTKGF GV+G DV+ +L
Sbjct: 132 GCLKKFVEDEYPEGVTEPLPLGFTFSYPASQSSINEGFLQRWTKGFDIDGVEGRDVVPML 191
Query: 196 QAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
Q A + ++ + VVAL NDT GTL++ + DPE ++G+I GTG N Y++ + K
Sbjct: 192 QEAIKKENVPIEVVALINDTTGTLVASAYTDPETKMGLIFGTGCNGAYYDVCGEIPKLEG 251
Query: 256 V---AARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLG 312
G +L IN E G FD++ VLP +KFD ID S GQQA EKMISG YLG
Sbjct: 252 QFHGDVAGESLMAINCEYGAFDNELA-VLPRSKFDHQIDAESPRPGQQAFEKMISGYYLG 310
Query: 313 EIARRVIVHLSSINCLPA-ALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGV 371
E+ R ++ LS+ + L ++ F I D L + Q+ G+
Sbjct: 311 EVLRLALLDLSAKGIFFKDQDLSKLNQPFILDTSFPARIEEDPYENLSDVQDLFQQELGI 370
Query: 372 DVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRR 431
E +IR + ++ R+A+LS A K + A A DGSVF K P F+
Sbjct: 371 QTTDAE-RSVIRRLAEVIGERSARLSVCGIAAI-CKKRGYKTAHAAADGSVFNKYPGFKE 428
Query: 432 VLQDNINRILGP---ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ I E + V A+DGSG+GAA I+A+
Sbjct: 429 RAAKGLRDIFQWETKEDPIIIVPAEDGSGVGAAVIAALTEKR 470
>ref|XP_001215959.1| hexokinase [Aspergillus terreus NIH2624]
gb|EAU33325.1| hexokinase [Aspergillus terreus NIH2624]
Length = 490
Score = 560 bits (1445), Expect = e-158, Method: Composition-based stats.
Identities = 148/471 (31%), Positives = 225/471 (47%), Gaps = 11/471 (2%)
Query: 8 ILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTV 67
I + + FT+ ++Q++ + + E+ +GL +
Sbjct: 4 IGPKRPPSRKGSRHELPQNLLQQIKEFEDIFTVDTAKLKQVVAHFVKELEKGLTVEGGNI 63
Query: 68 RMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGN 126
M ++V G F ALD+GGTN RV + +E D + S +++P+ G
Sbjct: 64 PMNVTWVMGFPDGNEQGTFLALDMGGTNLRVCEITLTEEKGAFDITQSKYRMPEELKTGT 123
Query: 127 ATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGV 186
A +L+ +IA +++ + + +PLGFTFS+P Q ++ G+L RWTKGF GV
Sbjct: 124 AEELWEYIADCLEQFINAHHENENLDKLPLGFTFSYPATQEYIDHGILQRWTKGFDIDGV 183
Query: 187 QGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFET 246
+G DV+ L+ + L + V AL NDT GTLI+ + DP +++G I GTG NA Y E
Sbjct: 184 EGQDVVPPLEEILKKRGLPIKVAALINDTTGTLIASAYTDPAIKIGCIFGTGVNAAYMED 243
Query: 247 ASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMI 306
+V K + IN E G FD+++ VLP TK+D ID S GQQA EKM
Sbjct: 244 VGSVPKLAYMNLPPDMPVAINCEYGAFDNEH-VVLPLTKYDHIIDRDSPRPGQQAFEKMT 302
Query: 307 SGMYLGEIARRVIVHLSSI--NCLPAALQTA-LGNRGSFESRFAGMISADRMPGLQFTRS 363
+G+YLGEI R ++ L + T+ L +S F I D LQ T
Sbjct: 303 AGLYLGEIFRLALLDLLESRPGLIFNGQDTSLLRKPYLLDSSFLAAIEEDPYENLQETSE 362
Query: 364 TIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVF 423
+++ + + +L +IR + L+ RAA+LSA A K + DGSVF
Sbjct: 363 LLERKLNIKA-TEAELEMIRRLAELIGTRAARLSACGVAAICTKK-NIKSCHVGADGSVF 420
Query: 424 EKIPSFRRVLQDNINRILGPE----CDVRAVLAKDGSGIGAAFISAMVVND 470
K P F+ + IL V + A+DGSG+GAA I+A+ +
Sbjct: 421 TKYPHFKARGAQALREILDWAPNEPDRVEILAAEDGSGVGAALIAALTLKR 471
>gb|AAG28789.1|AF309088_1 hexokinase [Tuber borchii]
Length = 497
Score = 559 bits (1442), Expect = e-157, Method: Composition-based stats.
Identities = 153/468 (32%), Positives = 237/468 (50%), Gaps = 17/468 (3%)
Query: 17 NDGETVRAVKRDVA--MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V D+ + L FT+ + ++++ E+V+GL T+ M P++V
Sbjct: 11 SRKGSMHDVPNDLMKHIHDLEKMFTIDTTKLHEVVSVFQEELVKGLSVTGGTIPMNPTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVACKEG-AVVDSSTSAFKIPKYALEGNATDLFGF 133
TG + ALD+GGTN RV V E D S +++P+ G LF +
Sbjct: 71 IGYPTGDETGTYLALDMGGTNLRVCEVELPEEQGQYDIYQSKYRLPEEIKSGTGEQLFDY 130
Query: 134 IASNVKKTMETRAP---EDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGND 190
IA VK+ + + + LGFTFS+P EQ ++ G+L RWTKGF +GV+G+D
Sbjct: 131 IAECVKQFLIANHEGQDIKDLKELHLGFTFSYPCEQNAIDHGILQRWTKGFDIEGVEGHD 190
Query: 191 VIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAV 250
V+ + + A R + + + AL NDT GTLI+ + D ++G I GTG NA Y ET +
Sbjct: 191 VVPMFEEALERKGVPIKITALVNDTTGTLIASAYTDNTTRIGCIFGTGCNAAYMETIGCI 250
Query: 251 TKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMY 310
K + S IN E G FD+++R VLP T +D ID+ S GQQ EKM++G+Y
Sbjct: 251 PKLAHMNLDPSLEIAINCEWGAFDNEHR-VLPRTVYDKHIDENSPRPGQQTFEKMVAGLY 309
Query: 311 LGEIARRVIVHLSSI---NCLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQK 367
LGEI R V+V L S + + L S ++ F I +D L T + +K
Sbjct: 310 LGEIFRLVLVDLYSNPDVSIFEKQDISTLQAEYSLDASFLAEIESDPWENLMETHALFEK 369
Query: 368 VCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIP 427
+ V + + ++IR + L+ RAA+L A A K + + DGSVF K P
Sbjct: 370 KLKI-VTTEPERKLIRRLAELIGTRAARLGACGVAAI-CKMKNIESCHVGADGSVFNKYP 427
Query: 428 SFRRVLQDNINRILGP-----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+F+ + I G + ++ V ++DGSG+GAA I+A+ +
Sbjct: 428 NFQERGAKALREIFGWGRTIRKDPIQIVPSEDGSGVGAALIAALTMKR 475
>ref|XP_717405.1| hexokinase II [Candida albicans SC5314]
gb|EAK98436.1| likely hexokinase II [Candida albicans SC5314]
Length = 484
Score = 559 bits (1440), Expect = e-157, Method: Composition-based stats.
Identities = 149/469 (31%), Positives = 240/469 (51%), Gaps = 14/469 (2%)
Query: 13 SIQGNDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRML 70
T V + A+ + QFT+S + +R I+ + + E+ GL + M+
Sbjct: 7 KPAQKRKGTFTDVSPQLLEALKPIQEQFTISADKLRAIVKHFISELDRGLSKAGGNIPMI 66
Query: 71 PSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDL 130
P +V + TG + A+DLGGTN RV+ V D++ S F +P + + +L
Sbjct: 67 PGWVMDFPTGKETGSYLAIDLGGTNLRVVLVKLGGNRDFDTTQSKFALPAHMRTATSDEL 126
Query: 131 FGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGND 190
+ FIA +K+ ++ P+ + +PLGFTFS+P Q ++N G+L RWTKG+S G++G D
Sbjct: 127 WDFIAKCLKEFVDEIYPDGCSEPLPLGFTFSYPASQNRINEGILQRWTKGWSIDGIEGKD 186
Query: 191 VIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAV 250
V+ +LQ A +V + ++VVAL NDT GTL++ + DPE ++G+I GTG N YF+ +
Sbjct: 187 VVPMLQKAIKKVGVPIDVVALINDTTGTLVASMYTDPEAKMGLIFGTGVNGAYFDVVKDI 246
Query: 251 TKDPAVAA---RGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMIS 307
K + IN E G+FD++ +++LP TK+D+ ID+ S GQQ EKMIS
Sbjct: 247 PKLEGKCPSDIPPESPMAINCEYGSFDNE-KYILPRTKYDVQIDEESPRPGQQTFEKMIS 305
Query: 308 GMYLGEIARRVIVHLSSIN--CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTI 365
G YLGE+ R +++ + L ++ + I D L
Sbjct: 306 GYYLGEVLRLILLEFAEEKKLIFKGQNLDKLKVPYVMDASYPSKIEEDPFENLSDVADLF 365
Query: 366 QKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEK 425
++ G++ + + +IIR + L+ R+A+ S A + + A A DGSV+ K
Sbjct: 366 REKLGIE-TTEPERKIIRCLAELIGERSARFSVCGIAAI-CQKRGYKTAHCAADGSVYNK 423
Query: 426 IPSFRRVLQDNINRILGPECDVR----AVLAKDGSGIGAAFISAMVVND 470
P F+ + I DV+ V A+DGSG+GAA I+A+
Sbjct: 424 YPGFKERTAQALRDIYEWPADVKDPIIIVPAEDGSGVGAAVIAALTEKR 472
>emb|CAC69958.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 557 bits (1437), Expect = e-157, Method: Composition-based stats.
Identities = 470/471 (99%), Positives = 470/471 (99%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLF FIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFDFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
>gb|EDU44499.1| hexokinase [Pyrenophora tritici-repentis Pt-1C-BFP]
Length = 483
Score = 557 bits (1435), Expect = e-157, Method: Composition-based stats.
Identities = 146/463 (31%), Positives = 233/463 (50%), Gaps = 17/463 (3%)
Query: 22 VRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADP 79
+ + +D+ + L F ++ + ++ I + + E+ +GL ++ M+P++
Sbjct: 1 MADMPKDLKTQIDKLEELFVVNTDKLKHITNHFVSELEKGLSEEGGSIPMIPTWCMAFPD 60
Query: 80 KRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNV 138
TG + ALD+GGTN RV V +E + S +++P+ G A +L+G++A +
Sbjct: 61 GHETGSYLALDMGGTNLRVCEVTLTEEKGEFEIIQSKYRMPEELKTGTADELWGYVADCL 120
Query: 139 KKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAA 198
++ +E + T+PLGFTFS+PV Q ++ GVL RWTKGF G++G DV+ + A
Sbjct: 121 QQFIEYHHEGEKLETLPLGFTFSYPVSQDAIDHGVLQRWTKGFDVAGMEGVDVVPGFKKA 180
Query: 199 FGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAA 258
+ + + AL NDT GT+I+ + + +++G I GTG NA Y E + K +
Sbjct: 181 LEDRGVPIKLAALVNDTTGTMIASAYTNTSIKIGCIFGTGCNAAYMEECGEIPKLKHMKL 240
Query: 259 RGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRV 318
IN E G FD++ + VLP T +D+ ID S GQQ EKM++G+YLGEI R V
Sbjct: 241 DPKLPMAINCEWGAFDNE-KKVLPRTPYDVIIDKESPRPGQQLFEKMVAGLYLGEIFRLV 299
Query: 319 IVHLSSIN---CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQS 375
++ L N + L S ++ F I DR LQ T Q+ G+
Sbjct: 300 LLDLHKGNECSMFEGQNASKLTKPYSLDAGFLSQIEEDRFENLQDTADLFQESLGITCTK 359
Query: 376 IEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQD 435
E L +IR + L+ RAA+L+A A K + + DGSVF K P F+
Sbjct: 360 PE-LELIRRLAELIGTRAARLTACGVSAI-CKHKKWDEVHVGADGSVFTKYPHFKIRQAQ 417
Query: 436 NINRILGP--------ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ I+ + + A+DGSG+GAA I+A+ V
Sbjct: 418 AMKEIMDWPAKYGKGKNDPIEVLPAEDGSGVGAALIAALTVKR 460
>ref|XP_822456.1| hexokinase [Trypanosoma brucei TREU927]
gb|EAN77628.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 555 bits (1432), Expect = e-156, Method: Composition-based stats.
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
>ref|XP_001502742.1| PREDICTED: similar to hexokinase domain containing 1 [Equus
caballus]
Length = 916
Score = 555 bits (1430), Expect = e-156, Method: Composition-based stats.
Identities = 162/497 (32%), Positives = 252/497 (50%), Gaps = 38/497 (7%)
Query: 2 SRRLNNILEHISI------------QGNDGETVRAVK-----RDVAMAALTNQFTMSVES 44
+RL+ ++ + V AV + + + F ++ E
Sbjct: 424 PKRLHKVVRRLVPNCDVRFLLSESGSAKGAAMVTAVASRVQAQRKQIDKVLALFRLTQEQ 483
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ + + E+ GL+ +TV+MLP+YV G F ALDLGGTNFRVL V
Sbjct: 484 LVGVQDKMRAELEYGLKRDTHSLATVKMLPTYVCGMPDGTEKGKFLALDLGGTNFRVLLV 543
Query: 102 ACK-EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTF 160
+ V F IP ++G +LF I + ++ + +PLGFTF
Sbjct: 544 KIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLK--GAQLPLGFTF 601
Query: 161 SFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGTL 219
SFP Q +++G LI WTKGF +G DV+ +L+ A R + +++VA+ NDTVGT+
Sbjct: 602 SFPCRQASIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTM 661
Query: 220 ISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRF 279
++ ++DP ++G+I GTGSN CY E + + IN E G F
Sbjct: 662 MTCGYEDPNCEIGLIAGTGSNLCYMEEMRNIELVEGDEGK----MCINTEWGGFGDNGCI 717
Query: 280 VLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALGN 338
T++D ++D+ SLN G+Q EKM SGMYLGEI R++++ L+ L + L
Sbjct: 718 DDIRTQYDKEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRT 777
Query: 339 RGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSA 398
RG FE++F I +DR+ LQ R +Q+ G+D + ED ++++VC V RAAQL
Sbjct: 778 RGIFETKFLSQIESDRLALLQ-VRRILQQ-LGLD-STCEDSIVVKEVCGAVSRRAAQLCG 834
Query: 399 SFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAK 453
+ A + K + R T+ +DG++++ P F R+LQ+ + L P CDV +L++
Sbjct: 835 AGLAAIVEKRREDQGLERLRITVGVDGTLYKLHPHFSRILQETVKE-LAPRCDVTFMLSE 893
Query: 454 DGSGIGAAFISAMVVND 470
DGSG GAA I+A+
Sbjct: 894 DGSGKGAALITAVAKRL 910
Score = 458 bits (1178), Expect = e-127, Method: Composition-based stats.
Identities = 152/456 (33%), Positives = 236/456 (51%), Gaps = 22/456 (4%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRA 82
+ + +S E++ IM EM +GL ++V+MLP++V
Sbjct: 17 DQIKKVDRFLYHMRLSDETLLDIMARFQAEMQKGLGKDTNPTASVKMLPTFVRAIPDGSE 76
Query: 83 TGVFYALDLGGTNFRVLRVAC--KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F +LDLGG+ FRVL+V + V + + P + GN +LF ++A +
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVSEEGKRNVQMESQFYPTPNEIIRGNGIELFEYVADCLAD 136
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
M T+ + + +PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A
Sbjct: 137 FMNTKGLKH--KRLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSCLTRAMK 194
Query: 201 RV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R + V+ +AL NDTVGT+++ + DP +VGVIIGTG+NACY E S + R
Sbjct: 195 RHKDINVDTLALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR 254
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
IN E G F T+FD ++D SLN G+Q EKMISG+YLGE+ R ++
Sbjct: 255 ----MCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLIL 310
Query: 320 VHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ ++ L +AL +G E+R + + GL TR + G++ S D
Sbjct: 311 LKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREILTD-LGLE-PSEAD 367
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVL 433
++ VC +V R+A L A+ A L + + R T+ +DG++++ P + + L
Sbjct: 368 CIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKLVRLRTTVGMDGTLYKIHPQYPKRL 427
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+ R++ P CDVR +L++ GS GAA ++A+
Sbjct: 428 HKVVRRLV-PNCDVRFLLSESGSAKGAAMVTAVASR 462
>ref|XP_460972.1| hypothetical protein DEHA0F15169g [Debaryomyces hansenii CBS767]
emb|CAG89330.1| unnamed protein product [Debaryomyces hansenii CBS767]
Length = 482
Score = 555 bits (1430), Expect = e-156, Method: Composition-based stats.
Identities = 153/440 (34%), Positives = 231/440 (52%), Gaps = 11/440 (2%)
Query: 39 TMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRV 98
T+S +++++I + + E+ +GL + + M+P +V + G + A+DLGGTN RV
Sbjct: 35 TVSPDTLKKITEHFIGELEKGLSKQGGNIPMIPGWVLDFPTGKEKGDYLAIDLGGTNLRV 94
Query: 99 LRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGF 158
+ V D++ S F +P+ + +L+ FIA +KK ++ P+ + +PLGF
Sbjct: 95 VLVKLGGNRDFDTTQSKFALPETMRTATSDELWTFIAECLKKFVQEEFPQGCTKPLPLGF 154
Query: 159 TFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGT 218
TFS+P Q +N GVL RWTKG+ GV+G+DV+ +LQ A +V + +NVVAL NDT GT
Sbjct: 155 TFSYPASQKSINTGVLQRWTKGWDIDGVEGHDVVPMLQKAIEKVGVPINVVALINDTTGT 214
Query: 219 LISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARG---SALTPINMESGNFDS 275
L++ + D E ++G+I GTG N Y++ S + K SA IN E G FD+
Sbjct: 215 LVASMYTDAETRMGLIYGTGCNGAYYDVVSDIPKLEGKMPSDVDQSAPMAINCEYGAFDN 274
Query: 276 KYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSIN--CLPAALQ 333
+ VLP TK+D+ ID S GQQ+ EKMISG YLGE+ R +++ L+
Sbjct: 275 EL-VVLPRTKYDILIDKQSPRPGQQSYEKMISGYYLGEVLRLILLDLAKEKKLIFKGQDL 333
Query: 334 TALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRA 393
+ L ++ F I D L T QK G+ S E +IIR + L+ R+
Sbjct: 334 SKLETEFILDTSFPSRIEEDPFENLSDTAELFQKELGIQTTSPE-RKIIRRLAELIGERS 392
Query: 394 AQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECD---VRAV 450
A+L A K + A A DGSV+ K P + + I E + V
Sbjct: 393 ARLFVCGIAAI-CKKRGYKTAHCAADGSVYNKYPGVKERTAKALRDIFEWETKEDLITIV 451
Query: 451 LAKDGSGIGAAFISAMVVND 470
A+DGSG+GAA I+A+
Sbjct: 452 HAEDGSGVGAAVIAALTEKR 471
>gb|AAA34697.1| hexokinase P-II peptide
prf||1110197A hexokinase PII
Length = 486
Score = 554 bits (1428), Expect = e-156, Method: Composition-based stats.
Identities = 147/466 (31%), Positives = 243/466 (52%), Gaps = 16/466 (3%)
Query: 18 DGETVRAVKRDVA--MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVY 75
++ V +++ + FT+ E+++ + + + E+ +GL + + M+P +V
Sbjct: 12 RKGSMADVPKELMQQIENFEKNFTVPTETLQAVTKHFISELEKGLSKKGGNIPMIPGWVM 71
Query: 76 KADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEG-NATDLFGFI 134
+ +G F A+DLGGTN RV+ V D++ S +++P N +L+ FI
Sbjct: 72 DFPTGKESGDFLAIDLGGTNLRVVLVKLGGDRTFDTTQSKYRLPDAMRTTQNPDELWEFI 131
Query: 135 ASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIAL 194
A ++K ++ + P+ ++ +PLGFTFSFP Q K+N G+L RWTKGF ++ +DV+ +
Sbjct: 132 ADSLKAFIDEQFPQGISEPIPLGFTFSFPASQNKINEGILQRWTKGFDIPNIENHDVVPM 191
Query: 195 LQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDP 254
LQ + ++ + VVAL NDT GTL++ Y+ DPE ++GVI GTG N Y++ S + K
Sbjct: 192 LQKQITKRNIPIEVVALINDTTGTLVASYYTDPETKMGVIFGTGVNGAYYDVCSDIEKLQ 251
Query: 255 A---VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYL 311
SA IN E G+FD+++ VLP TK+D+ ID+ S GQQ EKM SG YL
Sbjct: 252 GKLSDDIPPSAPMAINCEYGSFDNEH-VVLPRTKYDITIDEESPRPGQQTFEKMSSGYYL 310
Query: 312 GEIARRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
GEI R ++ + + + ++ + I D L+ T Q G
Sbjct: 311 GEILRLALMDMYKQGFIFKNQDLSKFDKPFVMDTSYPARIEEDPFENLEDTDDLFQNEFG 370
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ ++++ ++IR + L+ RAA+LS A + + IA DGSV + P F+
Sbjct: 371 I-NTTVQERKLIRRLSELIGARAARLSVCGIAAI-CQKRGYKTGHIAADGSVSTRYPGFK 428
Query: 431 RVLQDNINRILGP------ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ + I G + ++ V A+DGSG GAA I+A+
Sbjct: 429 EKAANALKDIYGWTQPHLDDYPIKVVPAEDGSGPGAAVIAALAQKR 474
>gb|AAA34699.1| hexokinase (HXK2)
Length = 486
Score = 553 bits (1426), Expect = e-155, Method: Composition-based stats.
Identities = 147/466 (31%), Positives = 243/466 (52%), Gaps = 16/466 (3%)
Query: 18 DGETVRAVKRDVA--MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVY 75
++ V +++ + FT+ E+++ + + + E+ +GL + + M+P +V
Sbjct: 12 RKGSMADVPKELMQQIENFEKNFTVPTETLQAVTKHFISELEKGLSKKGGNIPMIPGWVM 71
Query: 76 KADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEG-NATDLFGFI 134
+ +G F A+DLGGTN RV+ V D++ S +++P N +L+ FI
Sbjct: 72 DFPTGKESGDFLAIDLGGTNLRVVLVKLGGDRTFDTTQSKYRLPDAMRTTQNPDELWEFI 131
Query: 135 ASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIAL 194
A ++K ++ + P+ ++ +PLGFTFSFP Q K+N G+L RWTKGF ++ +DV+ +
Sbjct: 132 ADSLKAFIDEQFPQGISEPIPLGFTFSFPASQNKINEGILQRWTKGFDIPNIENHDVVPM 191
Query: 195 LQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDP 254
LQ + ++ + VVAL NDT GTL++ Y+ DPE ++GVI GTG N Y++ S + K
Sbjct: 192 LQKQITKRNIHIEVVALINDTTGTLVASYYTDPETKMGVIFGTGVNGAYYDVCSDIEKLQ 251
Query: 255 A---VAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYL 311
SA IN E G+FD+++ VLP TK+D+ ID+ S GQQ EKM SG YL
Sbjct: 252 GKLSDDIPPSAPMAINCEYGSFDNEH-VVLPRTKYDITIDEESPRPGQQTFEKMSSGYYL 310
Query: 312 GEIARRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
GEI R ++ + + + ++ + I D L+ T Q G
Sbjct: 311 GEILRLALMDMYKQGFIFKNQDLSKFDKPFVMDTSYPARIEEDPFENLEDTDDLFQNEFG 370
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ ++++ ++IR + L+ RAA+LS A + + IA DGSV + P F+
Sbjct: 371 I-NTTVQERKLIRRLSELIGARAARLSVCGIAAI-CQKRGYKTGHIAADGSVSTRYPGFK 428
Query: 431 RVLQDNINRILGP------ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ + I G + ++ V A+DGSG GAA I+A+
Sbjct: 429 EKAANALKDIYGWTQPHLDDYPIKVVPAEDGSGPGAAVIAALAQKR 474
>ref|XP_453567.1| HXK_KLULA [Kluyveromyces lactis]
sp|P33284|HXK_KLULA Hexokinase
emb|CAH00663.1| HXK_KLULA [Kluyveromyces lactis NRRL Y-1140]
Length = 485
Score = 552 bits (1423), Expect = e-155, Method: Composition-based stats.
Identities = 154/465 (33%), Positives = 251/465 (53%), Gaps = 15/465 (3%)
Query: 18 DGETVRAVKRDVA--MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVY 75
++ V ++ + L FT+S E MR I+ + + E+ +GL + + M+P +V
Sbjct: 12 RKGSMADVPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKGGNIPMIPGWVV 71
Query: 76 KADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIA 135
+ + TG F ALDLGGTN RV+ V D++ + +++P + G + L+ FIA
Sbjct: 72 EYPTGKETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIA 131
Query: 136 SNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALL 195
+K+ ++ P+ ++ +PLGFTFS+P Q K+N GVL RWTKGF +GV+G+DV+ +L
Sbjct: 132 KCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPML 191
Query: 196 QAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
Q ++++ +NVVAL NDT GTL++ + DP+ ++G+IIGTG N Y++ S + K
Sbjct: 192 QEQIEKLNIPINVVALINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEG 251
Query: 256 VAARG---SALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLG 312
+ + IN E G+FD+++ VLP TK+D+ ID+ S GQQA EKM SG YLG
Sbjct: 252 LLPEDIGPDSPMAINCEYGSFDNEH-LVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLG 310
Query: 313 EIARRVIVHLSSINCLPA-ALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGV 371
EI R V++ L + + L ++ + I D L+ T + +
Sbjct: 311 EIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNI 370
Query: 372 DVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRR 431
+ ++ + ++IR + LV RAA+L+ A + A IA DGSVF + P ++
Sbjct: 371 E-TTVVERKLIRKLAELVGTRAARLTVCGVSAI-CDKRGYKTAHIAADGSVFNRYPGYKE 428
Query: 432 VLQDNINRILGPEC------DVRAVLAKDGSGIGAAFISAMVVND 470
+ I + ++ V A+DGSG+GAA I+ +
Sbjct: 429 KAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKR 473
>ref|NP_079406.3| hexokinase domain containing 1 [Homo sapiens]
sp|Q2TB90|HKDC1_HUMAN Putative hexokinase HKDC1 (Hexokinase domain-containing protein 1)
gb|AAI10505.1| Hexokinase domain containing 1 [Homo sapiens]
gb|AAI10506.2| Hexokinase domain containing 1 [Homo sapiens]
gb|EAW54318.1| hexokinase domain containing 1, isoform CRA_b [Homo sapiens]
Length = 917
Score = 552 bits (1422), Expect = e-155, Method: Composition-based stats.
Identities = 164/497 (32%), Positives = 254/497 (51%), Gaps = 38/497 (7%)
Query: 2 SRRLNNILEHISIQ------------GNDGETVRAVK-----RDVAMAALTNQFTMSVES 44
+RL+ ++ + V AV + + + F ++ E
Sbjct: 424 PKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQ 483
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ + + E+ GL+ + +TVRMLP+YV G F ALDLGGTNFRVL V
Sbjct: 484 LVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLV 543
Query: 102 ACK-EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTF 160
+ V F IP ++G +LF I + ++ + ++PLGFTF
Sbjct: 544 KIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLK--GASLPLGFTF 601
Query: 161 SFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGTL 219
SFP Q +++G LI WTKGF +G DV+ +L+ A R + +++VA+ NDTVGT+
Sbjct: 602 SFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTM 661
Query: 220 ISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRF 279
++ ++DP ++G+I GTGSN CY E + G IN E G F
Sbjct: 662 MTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEG----GEGKMCINTEWGGFGDNGCI 717
Query: 280 VLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALGN 338
T++D ++D+ SLN G+Q EKM SGMYLGEI R++++ L+ L + L
Sbjct: 718 DDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRT 777
Query: 339 RGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSA 398
RG FE++F I +DR+ LQ R +Q+ G+D + ED ++++VC V RAAQL
Sbjct: 778 RGIFETKFLSQIESDRLALLQ-VRRILQQ-LGLD-STCEDSIVVKEVCGAVSRRAAQLCG 834
Query: 399 SFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAK 453
+ A + K + R T+ +DG++++ P F R+LQ+ + L P CDV +L++
Sbjct: 835 AGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKE-LAPRCDVTFMLSE 893
Query: 454 DGSGIGAAFISAMVVND 470
DGSG GAA I+A+
Sbjct: 894 DGSGKGAALITAVAKRL 910
Score = 460 bits (1184), Expect = e-127, Method: Composition-based stats.
Identities = 153/456 (33%), Positives = 238/456 (52%), Gaps = 22/456 (4%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGREST---VRMLPSYVYKADPKRA 82
+ + +S +++ IM EM +GL + V+MLP++V
Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76
Query: 83 TGVFYALDLGGTNFRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F +LDLGG+ FRVL+V E V + + P + GN T+LF ++A +
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
M+T+ + + +PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A
Sbjct: 137 FMKTKDLKH--KKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMR 194
Query: 201 RV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R + V+++AL NDTVGT+++ + DP +VGVIIGTG+NACY E S + R
Sbjct: 195 RHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR 254
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
IN E G F T+FD ++D SLN G+Q EKMISG+YLGE+ R ++
Sbjct: 255 ----MCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLIL 310
Query: 320 VHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ ++ L +AL +G E+R + + GL TR + G++ S D
Sbjct: 311 LKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREILVD-LGLE-PSEAD 367
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPL-----VKTQTQGRATIAIDGSVFEKIPSFRRVL 433
++ VC +V R+A L A+ A L K + R T+ +DG++++ P + + L
Sbjct: 368 CIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRL 427
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+ +++ P CDVR +L++ GS GAA ++A+
Sbjct: 428 HKVVRKLV-PSCDVRFLLSESGSTKGAAMVTAVASR 462
>dbj|BAF83713.1| unnamed protein product [Homo sapiens]
Length = 917
Score = 552 bits (1422), Expect = e-155, Method: Composition-based stats.
Identities = 164/497 (32%), Positives = 254/497 (51%), Gaps = 38/497 (7%)
Query: 2 SRRLNNILEHISIQ------------GNDGETVRAVK-----RDVAMAALTNQFTMSVES 44
+RL+ ++ + V AV + + + F ++ E
Sbjct: 424 PKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQ 483
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ + + E+ GL+ + +TVRMLP+YV G F ALDLGGTNFRVL V
Sbjct: 484 LVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLV 543
Query: 102 ACK-EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTF 160
+ V F IP ++G +LF I + ++ + ++PLGFTF
Sbjct: 544 KIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLK--GASLPLGFTF 601
Query: 161 SFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGTL 219
SFP Q +++G LI WTKGF +G DV+ +L+ A R + +++VA+ NDTVGT+
Sbjct: 602 SFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTM 661
Query: 220 ISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRF 279
++ ++DP ++G+I GTGSN CY E + G IN E G F
Sbjct: 662 MTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEG----GEGKMCINTEWGGFGDNGCI 717
Query: 280 VLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALGN 338
T++D ++D+ SLN G+Q EKM SGMYLGEI R++++ L+ L + L
Sbjct: 718 DDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRT 777
Query: 339 RGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSA 398
RG FE++F I +DR+ LQ R +Q+ G+D + ED ++++VC V RAAQL
Sbjct: 778 RGIFETKFLSQIESDRLALLQ-VRRILQQ-LGLD-STCEDSIVVKEVCGAVSRRAAQLCG 834
Query: 399 SFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAK 453
+ A + K + R T+ +DG++++ P F R+LQ+ + L P CDV +L++
Sbjct: 835 AGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKE-LAPRCDVTFMLSE 893
Query: 454 DGSGIGAAFISAMVVND 470
DGSG GAA I+A+
Sbjct: 894 DGSGKGAALITAVAKRL 910
Score = 460 bits (1183), Expect = e-127, Method: Composition-based stats.
Identities = 153/456 (33%), Positives = 238/456 (52%), Gaps = 22/456 (4%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGREST---VRMLPSYVYKADPKRA 82
+ + +S +++ IM EM +GL + V+MLP++V
Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76
Query: 83 TGVFYALDLGGTNFRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F +LDLGG+ FRVL+V E V + + P + GN T+LF ++A +
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNDIIRGNGTELFEYVADCLAD 136
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
M+T+ + + +PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A
Sbjct: 137 FMKTKDLKH--KKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMR 194
Query: 201 RV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R + V+++AL NDTVGT+++ + DP +VGVIIGTG+NACY E S + R
Sbjct: 195 RHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR 254
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
IN E G F T+FD ++D SLN G+Q EKMISG+YLGE+ R ++
Sbjct: 255 ----MCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLIL 310
Query: 320 VHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ ++ L +AL +G E+R + + GL TR + G++ S D
Sbjct: 311 LKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREILVD-LGLE-PSEAD 367
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPL-----VKTQTQGRATIAIDGSVFEKIPSFRRVL 433
++ VC +V R+A L A+ A L K + R T+ +DG++++ P + + L
Sbjct: 368 CIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRL 427
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+ +++ P CDVR +L++ GS GAA ++A+
Sbjct: 428 HKVVRKLV-PSCDVRFLLSESGSTKGAAMVTAVASR 462
>ref|XP_001660030.1| hexokinase [Aedes aegypti]
gb|EAT38748.1| hexokinase [Aedes aegypti]
Length = 461
Score = 551 bits (1420), Expect = e-155, Method: Composition-based stats.
Identities = 147/448 (32%), Positives = 231/448 (51%), Gaps = 9/448 (2%)
Query: 28 DVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEG---RESTVRMLPSYVYKADPKRATG 84
+ + +S + + +IM LL E+ GL E+ ++ +YV + G
Sbjct: 16 SKEIREQCQELILSDKQIEEIMRRLLKEINRGLGKATQPEADIKCFITYVQDLPNGKEKG 75
Query: 85 VFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMET 144
F ALDLGGTNFRVL + K+ + + + IP+ + G+ T LF IA + M+
Sbjct: 76 KFLALDLGGTNFRVLLIHLKDENDFEMLSKIYAIPQSIMLGSGTQLFDHIAECLANFMKE 135
Query: 145 RAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-S 203
+ +PLGFTFSFP+ Q + +G+L RWTKGF+ GV G DV+ LL+ A R
Sbjct: 136 HSV--YEEKLPLGFTFSFPLTQLGLTKGILARWTKGFNCSGVVGEDVVQLLKDAIARRGD 193
Query: 204 LKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSAL 263
+++ + A+ NDT GTL+S +K+ ++G+I+GTGSNACY E
Sbjct: 194 VQIEICAILNDTTGTLMSCAWKNHNCRIGLIVGTGSNACYVEKVENCEMFDGPKDPKKEH 253
Query: 264 TPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLS 323
IN E G F T++D +ID S+N G+Q EKMISGMY+GE+AR IV +
Sbjct: 254 VLINTEWGAFGDNGALDFVRTEYDREIDHFSINPGRQIQEKMISGMYMGELARLAIVKFT 313
Query: 324 SINCLPAAL-QTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRII 382
L + L RG F +++ I +D+ + R + G++ + ED +
Sbjct: 314 RAGLLFGGVGSDILFKRGQFFTKYVSEIESDKPGTYMYCRDVL-DELGLEHATDEDCANV 372
Query: 383 RDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILG 442
R +C V RAA L ++ A + K + T+ +DGSV+ P F +++ I + +
Sbjct: 373 RYICECVSSRAAHLVSAGIAALINKMDEKS-VTVGVDGSVYRFHPKFHDLMKAKIRQFVK 431
Query: 443 PECDVRAVLAKDGSGIGAAFISAMVVND 470
P+ +L++DGSG GAA ++A+ +
Sbjct: 432 PDISFDLMLSEDGSGRGAALVAAVACRE 459
>ref|XP_001110556.1| PREDICTED: similar to hexokinase domain containing 1 [Macaca
mulatta]
Length = 917
Score = 550 bits (1419), Expect = e-155, Method: Composition-based stats.
Identities = 163/497 (32%), Positives = 255/497 (51%), Gaps = 38/497 (7%)
Query: 2 SRRLNNILEHISIQ------------GNDGETVRAVK-----RDVAMAALTNQFTMSVES 44
+RL+ ++ + V AV + + + F ++ E
Sbjct: 424 PKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFRLTREQ 483
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ + + E+ GL+ + +TVRMLP+YV G F ALDLGGTNFRVL V
Sbjct: 484 LVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLV 543
Query: 102 ACK-EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTF 160
+ V F IP ++G +LF I + ++ + ++PLGFTF
Sbjct: 544 KIRSGRRSVRMYNKIFAIPLGIMQGTGEELFDHIVQCIADFLDYMGLK--GASLPLGFTF 601
Query: 161 SFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGTL 219
SFP Q +++G LI WTKGF +G DV+ +L+ A R + +++VA+ NDTVGT+
Sbjct: 602 SFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTM 661
Query: 220 ISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRF 279
++ ++DP ++G+I GTGSN CY E + + IN E G F
Sbjct: 662 MTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGDEGK----MCINTEWGGFGDNGCI 717
Query: 280 VLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALGN 338
T++D ++D+ SLN G+Q EKM SGMYLGEI R++++ L+ L + L
Sbjct: 718 DDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRT 777
Query: 339 RGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSA 398
RG FE++F I +DR+ LQ R+ +Q+ G+D + ED ++++VC V RAAQL
Sbjct: 778 RGIFETKFLSQIESDRLALLQ-VRTILQQ-LGLD-STCEDSIVVKEVCGAVSRRAAQLCG 834
Query: 399 SFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAK 453
+ A + K + R T+ +DG++++ P F R+LQ+ + L P CDV +L++
Sbjct: 835 AGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKE-LAPRCDVTFMLSE 893
Query: 454 DGSGIGAAFISAMVVND 470
DGSG GAA I+A+
Sbjct: 894 DGSGKGAALITAVAKRL 910
Score = 461 bits (1188), Expect = e-128, Method: Composition-based stats.
Identities = 152/456 (33%), Positives = 238/456 (52%), Gaps = 22/456 (4%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGREST---VRMLPSYVYKADPKRA 82
+ + +S +++ IM EM +GL + V+MLP++V
Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76
Query: 83 TGVFYALDLGGTNFRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F +LDLGG+ FRVL+V E V + + P + GN T+LF ++A +
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
M+T+ + + +PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A
Sbjct: 137 FMKTKDLKH--KKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMR 194
Query: 201 RV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R + V+++A+ NDTVGT+++ + DP +VGVIIGTG+NACY E S + R
Sbjct: 195 RHKDMDVDILAVVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR 254
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
IN E G F T+FD ++D SLN G+Q EKMISG+YLGE+ R ++
Sbjct: 255 ----MCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQMFEKMISGLYLGELVRLIL 310
Query: 320 VHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ ++ L +AL +G E+R + + GL TR + G++ S D
Sbjct: 311 LKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREILVD-LGLE-PSEAD 367
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPL-----VKTQTQGRATIAIDGSVFEKIPSFRRVL 433
++ VC +V R+A L A+ A L K + R T+ +DG++++ P + + L
Sbjct: 368 CIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGVDGTLYKIHPQYPKRL 427
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+ +++ P CDVR +L++ GS GAA ++A+
Sbjct: 428 HKVVRKLV-PSCDVRFLLSESGSTKGAAMVTAVASR 462
>ref|NP_663394.1| hexokinase domain containing 1 [Mus musculus]
sp|Q91W97|HKDC1_MOUSE Putative hexokinase HKDC1 (Hexokinase domain-containing protein 1)
gb|AAH16235.1| Hexokinase domain containing 1 [Mus musculus]
gb|EDL32102.1| hexokinase domain containing 1 [Mus musculus]
Length = 915
Score = 550 bits (1419), Expect = e-155, Method: Composition-based stats.
Identities = 162/496 (32%), Positives = 256/496 (51%), Gaps = 38/496 (7%)
Query: 2 SRRLNNILEHISI------------QGNDGETVRAVK-----RDVAMAALTNQFTMSVES 44
+RL+ ++ + V AV + + + F ++ E
Sbjct: 424 PKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLTREQ 483
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ + + E+ GL+ + +TV+MLP+YVY G F ALDLGGTNFRVL V
Sbjct: 484 LLGVRDKMRAELEYGLKKKTHSLATVKMLPTYVYGMPDGTEKGKFLALDLGGTNFRVLLV 543
Query: 102 ACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFS 161
+ V F IP ++G +LF I + ++ + +PLGFTFS
Sbjct: 544 KIR-RRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLK--GAQLPLGFTFS 600
Query: 162 FPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGTLI 220
FP QT +++G L+ WTKGF +G DV+ +L+ A R + +++VA+ NDTVGT++
Sbjct: 601 FPCRQTCIDKGTLVGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAIVNDTVGTMM 660
Query: 221 SHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFV 280
+ ++DP ++G+I GTGSN CY E + R +N E G F
Sbjct: 661 TCGYEDPRCEIGLIAGTGSNVCYMEEMRNIELVDGDEGR----MCVNTEWGGFGDNGCID 716
Query: 281 LPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALGNR 339
T++D ++D+ SLN G+Q EKM SGMYLGEI RR+++ L+ L + L R
Sbjct: 717 DIRTQYDKEVDEGSLNAGKQRYEKMTSGMYLGEIVRRILIDLTRQGLLFRGQISERLRTR 776
Query: 340 GSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSAS 399
G FE++F I +DR+ LQ R +Q+ G+D + ED ++++VC V RAAQ+ +
Sbjct: 777 GIFETKFLSQIESDRLALLQ-VRRILQQ-LGLD-STCEDSIVVKEVCGAVSRRAAQMCGA 833
Query: 400 FCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAKD 454
A + K + + T+ +DG++++ P F R+LQ+ + L P+CDV +L++D
Sbjct: 834 GMAAIVEKRREDQGLQHFKVTVGVDGTLYKLHPHFSRILQETVKE-LAPQCDVTFMLSED 892
Query: 455 GSGIGAAFISAMVVND 470
GSG GAA I+A+
Sbjct: 893 GSGKGAALITAVAKRL 908
Score = 488 bits (1256), Expect = e-136, Method: Composition-based stats.
Identities = 150/456 (32%), Positives = 237/456 (51%), Gaps = 22/456 (4%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRA 82
+ + +S E++ IM EM +GL ++V+MLP++V
Sbjct: 17 DQIKKVDRFLYHMRLSDETLVDIMARFQAEMEKGLGKDTNPTASVKMLPTFVRAIPDGSE 76
Query: 83 TGVFYALDLGGTNFRVLRVAC--KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F +LDLGG+ FRVL+V + V + + +P GN T+LF ++A +
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVSQEGQQNVQMESQFYPMPNEITRGNGTELFDYVADCLAD 136
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
M+T+ + +PLGFTFSFP Q K+ GVL+ WTK F +GVQ DV+ L A
Sbjct: 137 FMKTKNLTH--KKLPLGFTFSFPCRQNKLEEGVLLSWTKKFKARGVQDTDVVNRLATAMK 194
Query: 201 RV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
+ L V+++AL NDTVGT+++ + DP +VGVIIGTG+NACY E S + R
Sbjct: 195 KHKDLDVDILALVNDTVGTMMTCAYDDPNCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR 254
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
IN E G F T+FD ++D SLN G+Q EKMISG+Y+GE+ R ++
Sbjct: 255 ----MCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYMGELVRLIL 310
Query: 320 VHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ ++ + L +AL +G E++ + + GL TR + G++ S D
Sbjct: 311 LKMAKVGLLFGGAKSSALHTKGKIETQHVAAMEMSK-EGLANTREILVD-LGLE-PSESD 367
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVL 433
++ VC +V R+A L A+ L + + R T+ +DG++++ P + + L
Sbjct: 368 CIAVQHVCTIVSFRSANLCAAALATILTRLRENKKLARLRTTVGMDGTLYKTHPQYPKRL 427
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+ R++ P CDVR +L++ GS GAA ++A+
Sbjct: 428 HKVVRRLV-PNCDVRFLLSESGSTKGAAMVTAVASR 462
>gb|AAH12337.1| HKDC1 protein [Homo sapiens]
Length = 677
Score = 550 bits (1419), Expect = e-155, Method: Composition-based stats.
Identities = 164/497 (32%), Positives = 254/497 (51%), Gaps = 38/497 (7%)
Query: 2 SRRLNNILEHISIQ------------GNDGETVRAVK-----RDVAMAALTNQFTMSVES 44
+RL+ ++ + V AV + + + F ++ E
Sbjct: 184 PKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQ 243
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ + + E+ GL+ + +TVRMLP+YV G F ALDLGGTNFRVL V
Sbjct: 244 LVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLV 303
Query: 102 ACK-EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTF 160
+ V F IP ++G +LF I + ++ + ++PLGFTF
Sbjct: 304 KIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLK--GASLPLGFTF 361
Query: 161 SFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGTL 219
SFP Q +++G LI WTKGF +G DV+ +L+ A R + +++VA+ NDTVGT+
Sbjct: 362 SFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTM 421
Query: 220 ISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRF 279
++ ++DP ++G+I GTGSN CY E + G IN E G F
Sbjct: 422 MTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEG----GEGKMCINTEWGGFGDNGCI 477
Query: 280 VLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALGN 338
T++D ++D+ SLN G+Q EKM SGMYLGEI R++++ L+ L + L
Sbjct: 478 DDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRT 537
Query: 339 RGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSA 398
RG FE++F I +DR+ LQ R +Q+ G+D + ED ++++VC V RAAQL
Sbjct: 538 RGIFETKFLSQIESDRLALLQ-VRRILQQ-LGLD-STCEDSIVVKEVCGAVSRRAAQLCG 594
Query: 399 SFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAK 453
+ A + K + R T+ +DG++++ P F R+LQ+ + L P CDV +L++
Sbjct: 595 AGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKE-LAPRCDVTFMLSE 653
Query: 454 DGSGIGAAFISAMVVND 470
DGSG GAA I+A+
Sbjct: 654 DGSGKGAALITAVAKRL 670
Score = 208 bits (530), Expect = 8e-52, Method: Composition-based stats.
Identities = 68/230 (29%), Positives = 112/230 (48%), Gaps = 14/230 (6%)
Query: 246 TASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKM 305
S + R IN E G F T+FD ++D SLN G+Q EKM
Sbjct: 1 DMSNIDLVEGDEGR----MCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKM 56
Query: 306 ISGMYLGEIARRVIVHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRST 364
ISG+YLGE+ R +++ ++ L +AL +G E+R + + GL TR
Sbjct: 57 ISGLYLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREI 115
Query: 365 IQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPL-----VKTQTQGRATIAID 419
+ G++ S D ++ VC +V R+A L A+ A L K + R T+ +D
Sbjct: 116 LVD-LGLE-PSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMD 173
Query: 420 GSVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
G++++ P + + L + +++ P CDVR +L++ GS GAA ++A+
Sbjct: 174 GTLYKIHPQYPKRLHKVVRKLV-PSCDVRFLLSESGSTKGAAMVTAVASR 222
>emb|CAH71500.1| hexokinase domain containing 1 [Homo sapiens]
Length = 917
Score = 550 bits (1417), Expect = e-154, Method: Composition-based stats.
Identities = 164/497 (32%), Positives = 254/497 (51%), Gaps = 38/497 (7%)
Query: 2 SRRLNNILEHISIQ------------GNDGETVRAVK-----RDVAMAALTNQFTMSVES 44
+RL+ ++ + V AV + + + F ++ E
Sbjct: 424 PKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQ 483
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ + + E+ GL+ + +TVRMLP+YV G F ALDLGGTNFRVL V
Sbjct: 484 LVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLV 543
Query: 102 ACK-EGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTF 160
+ V F IP ++G +LF I + ++ + ++PLGFTF
Sbjct: 544 KIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLK--GASLPLGFTF 601
Query: 161 SFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGTL 219
SFP Q +++G LI WTKGF +G DV+ +L+ A R + +++VA+ NDTVGT+
Sbjct: 602 SFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTM 661
Query: 220 ISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRF 279
++ ++DP ++G+I GTGSN CY E + G IN E G F
Sbjct: 662 MTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEG----GEGKMCINTEWGGFGDNGCI 717
Query: 280 VLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALGN 338
T++D ++D+ SLN G+Q EKM SGMYLGEI R++++ L+ L + L
Sbjct: 718 DDIWTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRT 777
Query: 339 RGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSA 398
RG FE++F I +DR+ LQ R +Q+ G+D + ED ++++VC V RAAQL
Sbjct: 778 RGIFETKFLSQIESDRLALLQ-VRRILQQ-LGLD-STCEDSIVVKEVCGAVSRRAAQLCG 834
Query: 399 SFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAK 453
+ A + K + R T+ +DG++++ P F R+LQ+ + L P CDV +L++
Sbjct: 835 AGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKE-LAPRCDVTFMLSE 893
Query: 454 DGSGIGAAFISAMVVND 470
DGSG GAA I+A+
Sbjct: 894 DGSGKGAALITAVAKRL 910
Score = 460 bits (1185), Expect = e-128, Method: Composition-based stats.
Identities = 153/456 (33%), Positives = 238/456 (52%), Gaps = 22/456 (4%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGREST---VRMLPSYVYKADPKRA 82
+ + +S +++ IM EM +GL + V+MLP++V
Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76
Query: 83 TGVFYALDLGGTNFRVLRVACKEGAV--VDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F +LDLGG+ FRVL+V E V + + P + GN T+LF ++A +
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
M+T+ + + +PLG TFSFP QTK+ GVL+ WTK F +GVQ DV++ L A
Sbjct: 137 FMKTKDLKH--KKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMR 194
Query: 201 RV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R + V+++AL NDTVGT+++ + DP +VGVIIGTG+NACY E S + R
Sbjct: 195 RHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR 254
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
IN E G F T+FD ++D SLN G+Q EKMISG+YLGE+ R ++
Sbjct: 255 ----MCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLIL 310
Query: 320 VHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ ++ L +AL +G E+R + + GL TR + G++ S D
Sbjct: 311 LKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYK-EGLANTREILVD-LGLE-PSEAD 367
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPL-----VKTQTQGRATIAIDGSVFEKIPSFRRVL 433
++ VC +V R+A L A+ A L K + R T+ +DG++++ P + + L
Sbjct: 368 CIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRL 427
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVN 469
+ +++ P CDVR +L++ GS GAA ++A+
Sbjct: 428 HKVVRKLV-PSCDVRFLLSESGSTKGAAMVTAVASR 462
>emb|CAA43855.1| hexakinase [Kluyveromyces lactis]
Length = 485
Score = 550 bits (1417), Expect = e-154, Method: Composition-based stats.
Identities = 153/465 (32%), Positives = 250/465 (53%), Gaps = 15/465 (3%)
Query: 18 DGETVRAVKRDVA--MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVY 75
++ V ++ + L FT+S E MR I+ + + E+ +GL + + M+P +V
Sbjct: 12 RKGSMADVPANLMEQIHGLETLFTVSSEKMRSIVKHFISELDKGLSKKGGNIPMIPGWVV 71
Query: 76 KADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIA 135
+ + TG F ALDLGGTN RV+ V D++ + +++P + G + L+ FIA
Sbjct: 72 EYPTGKETGDFLALDLGGTNLRVVLVKLGGNHDFDTTQNKYRLPDHLRTGTSEQLWSFIA 131
Query: 136 SNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALL 195
+K+ ++ P+ ++ +PLGFTFS+P Q K+N GVL RWTKGF +GV+G+DV+ +L
Sbjct: 132 KCLKEFVDEWYPDGVSEPLPLGFTFSYPASQKKINSGVLQRWTKGFDIEGVEGHDVVPML 191
Query: 196 QAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
Q ++++ +NVV L NDT GTL++ + DP+ ++G+IIGTG N Y++ S + K
Sbjct: 192 QEQIEKLNIPINVVRLINDTTGTLVASLYTDPQTKMGIIIGTGVNGAYYDVVSGIEKLEG 251
Query: 256 VAARG---SALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLG 312
+ + IN E G+FD+++ VLP TK+D+ ID+ S GQQA EKM SG YLG
Sbjct: 252 LLPEDIGPDSPMAINCEYGSFDNEH-LVLPRTKYDVIIDEESPRPGQQAFEKMTSGYYLG 310
Query: 313 EIARRVIVHLSSINCLPA-ALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGV 371
EI R V++ L + + L ++ + I D L+ T + +
Sbjct: 311 EIMRLVLLDLYDSGFIFKDQDISKLKEAYVMDTSYPSKIEDDPFENLEDTDDLFKTNLNI 370
Query: 372 DVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRR 431
+ ++ + ++IR + LV RAA+L+ A + A IA DGSVF + P ++
Sbjct: 371 E-TTVVERKLIRKLAELVGTRAARLTVCGVSAI-CDKRGYKTAHIAADGSVFNRYPGYKE 428
Query: 432 VLQDNINRILGPEC------DVRAVLAKDGSGIGAAFISAMVVND 470
+ I + ++ V A+DGSG+GAA I+ +
Sbjct: 429 KAAQALKDIYNWDVEKMEDHPIQLVAAEDGSGVGAAIIACLTQKR 473
>gb|AAP40021.1| hexokinase [Nicotiana benthamiana]
Length = 497
Score = 549 bits (1416), Expect = e-154, Method: Composition-based stats.
Identities = 152/480 (31%), Positives = 234/480 (48%), Gaps = 23/480 (4%)
Query: 11 HISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRE-STVRM 69
+ + ++ + + + + ++Q+ + EM GL S ++M
Sbjct: 21 ALIVNHRMRKSSKWARAMAILREFEEKCGTPDAKLKQVADAMTVEMHAGLASEGGSKLKM 80
Query: 70 LPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKE--GAVVDSSTSAFKIPKYALEGNA 127
L +YV GVFYALDLGGTNFRVLRV G ++ + IP + G +
Sbjct: 81 LITYVDNLPTGDEAGVFYALDLGGTNFRVLRVQLGGKDGGIIHQEFAEASIPPNLMVGTS 140
Query: 128 TDLFGFIASNVKKTMETRAP---EDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTK 184
+LF +IA+ + K + + + LGFTFSFPV QT +N G ++RWTKGFS
Sbjct: 141 EELFDYIAAELAKFVAEEEEKFQQPPGKQRELGFTFSFPVMQTSINSGTIMRWTKGFSID 200
Query: 185 GVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYF 244
G DV+ L A R + + V AL NDTVGTL + +V V VI+GTG+NA Y
Sbjct: 201 DAVGQDVVGELTKAMKRKGVDMRVSALVNDTVGTLAGGKYTHNDVAVAVILGTGTNAAYV 260
Query: 245 ETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEK 304
E A+ K + INME GNF S + LP T++D +D SLN G Q EK
Sbjct: 261 ERVQAIPKWHGPMPKS-GEMVINMEWGNFRSSH---LPLTQYDHALDTNSLNPGDQIFEK 316
Query: 305 MISGMYLGEIARRVIVHLSSINCLPA-ALQTALGNRGSFESRFAGMISADRMPGLQFTRS 363
M SGMYLGEI RRV++ ++ + + L + + + D L+
Sbjct: 317 MTSGMYLGEILRRVLLRMAEEAGIFGDEVPPKLKSPFVLRTPDMSAMHHDTSSDLRVVGD 376
Query: 364 TIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQ-------GRATI 416
++ + + S++ R++ ++C +V R A+L+A+ L K + +
Sbjct: 377 KLKDILEISNTSLKTRRLVVELCNIVATRGARLAAAGVLGILKKMGRDTPRQGGPQKMVV 436
Query: 417 AIDGSVFEKIPSFRRVLQDNINRILGPEC--DVRAVLAKDGSGIGAAFISA---MVVNDK 471
A+DG ++E +R L++ + +LG E + + DGSGIGAA ++A M + DK
Sbjct: 437 AMDGGLYEHYAEYRTCLENTLKELLGDELATSIVFEHSNDGSGIGAALLAASNSMYLEDK 496
>ref|XP_421579.2| PREDICTED: similar to Hexokinase domain containing 1 [Gallus
gallus]
Length = 917
Score = 549 bits (1416), Expect = e-154, Method: Composition-based stats.
Identities = 165/498 (33%), Positives = 258/498 (51%), Gaps = 39/498 (7%)
Query: 2 SRRLNNILEHISI------------QGNDGETVRAVK-----RDVAMAALTNQFTMSVES 44
+RL+ ++ + V AV + + A+ F +++E+
Sbjct: 424 PKRLHKVVRRLVPNCDVRFLLSQSGSAKGAAMVTAVAHRLAAQRKKIDAVLAPFVLTLET 483
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+R + + E+ GL+ +TV+MLP+YV G + ALDLGGTNFRVL V
Sbjct: 484 LRDVKNKMRTELEYGLKRETQDRATVKMLPTYVCGTPDGTEKGKYLALDLGGTNFRVLLV 543
Query: 102 ACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFT 159
+ G V F IP ++G +LF I + +E + +PLGFT
Sbjct: 544 KIRSGRRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLEYMGIK--GARLPLGFT 601
Query: 160 FSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGT 218
FSFP Q +++G L+ WTKGF +G DV+ +L+ A R + +++VA+ NDTVGT
Sbjct: 602 FSFPCRQASIDKGTLVGWTKGFKATDCEGEDVVDMLREAIRRRNEFDLDIVAVVNDTVGT 661
Query: 219 LISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYR 278
+++ ++DP ++G+I GTGSN CY E + + IN E G F
Sbjct: 662 MMTCGYEDPNCEIGLIAGTGSNVCYMEDMKNIEIVDGNEGK----MCINTEWGGFGDNGC 717
Query: 279 FVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALG 337
TK+D ++D+ SLN G+Q EKM SGMYLGEI R++++ L+ L + +L
Sbjct: 718 IDNIRTKYDKEVDEGSLNAGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISESLR 777
Query: 338 NRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLS 397
RG FE++F I +DR+ LQ R +Q+ G+D + +D I+++VC V RAAQL
Sbjct: 778 KRGIFETKFLSQIESDRLALLQ-VRRILQQ-LGLD-STCDDSIIVKEVCGAVSRRAAQLC 834
Query: 398 ASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLA 452
+ A + K + + T+ +DG++++ P F RVLQ+ + L P CDV +L+
Sbjct: 835 GAGLAAIVEKKRENRGAEHLQITVGVDGTLYKLHPHFSRVLQETVKE-LAPRCDVTFMLS 893
Query: 453 KDGSGIGAAFISAMVVND 470
+DGSG GAA I+A+
Sbjct: 894 EDGSGKGAALITAVAKRL 911
Score = 442 bits (1137), Expect = e-122, Method: Composition-based stats.
Identities = 146/457 (31%), Positives = 236/457 (51%), Gaps = 22/457 (4%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKRA 82
+ + +S + + +M EMV+GL +TV+MLPS+V
Sbjct: 17 DQIKKVDRYLYHMRLSDDVLLDVMARFQAEMVKGLGRDTNPTATVKMLPSFVRSLPDGSE 76
Query: 83 TGVFYALDLGGTNFRVLRVAC--KEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F A+DLGG+ FR L+V + + PK ++G+ +LF ++A +
Sbjct: 77 KGDFLAVDLGGSQFRALKVKVFNDGKQSSQLESEFYPTPKEVIQGSGAELFSYVADCLSD 136
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
ME+R + +PLGFTFSFP +QTK+ G+L+ WTK F +GVQG DV++ L+ A
Sbjct: 137 FMESRNLKH--EKLPLGFTFSFPCKQTKLEEGILLSWTKHFKARGVQGTDVVSSLRNALQ 194
Query: 201 RV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
+ + V+V+A+ NDTVGT+++ + DP ++G+IIGTG+NACY E + R
Sbjct: 195 KHKDIDVDVLAMVNDTVGTMMTCGYDDPRCEIGLIIGTGTNACYMEEMRHINLVEGDEGR 254
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
IN E G F T+FD ++D SLN G+Q EKMIS +YLGE+ R ++
Sbjct: 255 ----MCINTEWGAFGDDGALDDLRTEFDRELDLGSLNPGKQLFEKMISSLYLGELVRLIL 310
Query: 320 VHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
+ ++ L + AL +G E + + + GL T+ + + + S +D
Sbjct: 311 LKMTKEGLLFNGKVSAALLTKGKIEMKHVSAMEKYK-EGLSNTKEILTE-LNL-FPSEDD 367
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVL 433
++ VC +V R+A L A+ A L + + R T+ IDG +++ P + + L
Sbjct: 368 CIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKLLRLRTTVGIDGGLYKTHPQYPKRL 427
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVND 470
+ R++ P CDVR +L++ GS GAA ++A+
Sbjct: 428 HKVVRRLV-PNCDVRFLLSQSGSAKGAAMVTAVAHRL 463
>ref|XP_001525198.1| hexokinase [Lodderomyces elongisporus NRRL YB-4239]
gb|EDK44947.1| hexokinase [Lodderomyces elongisporus NRRL YB-4239]
Length = 485
Score = 549 bits (1415), Expect = e-154, Method: Composition-based stats.
Identities = 157/465 (33%), Positives = 246/465 (52%), Gaps = 15/465 (3%)
Query: 18 DGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVY 75
+ V + + L QFT+S E++R+I+ + + E+ +GL + M+P +V
Sbjct: 12 RKGSFTDVSPQLMEELNELEKQFTVSGETLRKIVDHFITELDKGLSKAGGNIPMIPGWVM 71
Query: 76 KADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIA 135
+ TG + A+DLGGTN RV+ V D++ S F +P + +L+ FIA
Sbjct: 72 DFPTGKETGDYLAIDLGGTNLRVVLVKLGGNRDFDTTQSKFPLPSNMRTATSEELWSFIA 131
Query: 136 SNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALL 195
+ +K E P + +PLGFTFS+P Q + +GVL RWTKG++ +GV+G+DV+ +L
Sbjct: 132 NCLKTFFEEEFPNGVEEPLPLGFTFSYPASQNTITQGVLQRWTKGWAIEGVEGHDVVPML 191
Query: 196 QAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPA 255
Q+A +V + V +VA+ NDTVGTL++ + DPE ++G+I GTG N Y++ + K
Sbjct: 192 QSAIEKVQVPVKIVAVINDTVGTLVASNYTDPEAKLGLIFGTGVNGAYYDVVGDIPKLEG 251
Query: 256 VAARG---SALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLG 312
+ IN E G+FD++ +F+LP K+D+ ID+ S GQQ EKM SG YLG
Sbjct: 252 KLESDIGVDSPMAINCEYGSFDNE-KFILPRNKYDVMIDEESPRPGQQTFEKMNSGYYLG 310
Query: 313 EIARRVIVHLSSIN--CLPAALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
EI R V+V L+ T L ++ F I D L + Q V G
Sbjct: 311 EILRLVLVDLAENKKVIFKNQDLTKLNEVYILDTSFPAKIEEDPFENLSDVQEIFQSVLG 370
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
++ ++ + ++IR + L+ R+A+LS A K + A A DGSV+ K P F+
Sbjct: 371 LE-TTVPERKVIRRIAELIGNRSARLSVCGIAAI-CKKRGYKTAHCAADGSVYSKYPDFK 428
Query: 431 RVLQDNINRILGPECDVR-----AVLAKDGSGIGAAFISAMVVND 470
+ ++ I DV+ V A+DGSG+GAA I+A+
Sbjct: 429 QRAAQSLRDIFEWSDDVKEDPILIVDAEDGSGVGAAIIAALTEKR 473
>gb|AAL93565.1|AF488830_1 hexokinase [Trypanosoma cruzi]
emb|CAD26835.1| hexokinase [Trypanosoma cruzi]
Length = 471
Score = 549 bits (1415), Expect = e-154, Method: Composition-based stats.
Identities = 315/471 (66%), Positives = 385/471 (81%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MS RLNN+L+HI+++ D +T+R +K+ +A+A+L NQFT+ + ++Q+M Y++++M+EGL
Sbjct: 1 MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHQMIEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGREST+RMLPSYVYK DP +ATGVFYALDLGGTNFRVLRV CKEG V D + F IP+
Sbjct: 61 EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL+G A DLFGFIA +VKK ME +APEDLNRTVPLGFTFSFP EQ V+ G LI+WTKG
Sbjct: 121 QALQGTAEDLFGFIAQSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDHGFLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FST+GV+G DV+ LLQ A R+ +KV VVALCNDTVGTLI++YF DP+ QVGVIIGTGSN
Sbjct: 181 FSTRGVEGKDVVELLQKALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE A AVTK+P+VAARG+ TPINME GNFDSKY+FVLP T +D +D + N+ Q
Sbjct: 241 ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNFQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EKM+SGMYLGEI+RR+I HL+ ++CLP+AL + + SFE++F GMISADRMPGLQF
Sbjct: 301 TQEKMVSGMYLGEISRRMIAHLAELHCLPSALASKMAKPWSFETKFMGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR Q++ VDV + DL +IRDVC LVRGRAAQ+SA FC APLVKT+ +GRAT+AIDG
Sbjct: 361 TRQVFQELFQVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEK PSFRR+LQ N+N ILGP CDV LA+DGSGIGAAFISA+VVNDK
Sbjct: 421 SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK 471
>ref|NP_985826.1| AFR279Cp [Ashbya gossypii ATCC 10895]
gb|AAS53650.1| AFR279Cp [Ashbya gossypii ATCC 10895]
Length = 488
Score = 549 bits (1415), Expect = e-154, Method: Composition-based stats.
Identities = 158/466 (33%), Positives = 249/466 (53%), Gaps = 16/466 (3%)
Query: 18 DGETVRAVKRDVA--MAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYVY 75
++ V + + +A+ FT+S E +++I + + E+ +GL + + M+P +V
Sbjct: 12 RKGSMADVPKTLVEQIASFERIFTVSAEKLQEITKHFVTELDKGLSKKGGNIPMIPGWVM 71
Query: 76 KADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEG-NATDLFGFI 134
TG + A+DLGGTN RV+ V D++ S +++P NA++L+ FI
Sbjct: 72 DYPTGNETGDYLAIDLGGTNLRVVLVKLLGNHQFDTTQSKYRLPNRMRTTQNASELWDFI 131
Query: 135 ASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIAL 194
A ++K +E + PE +++T+PLGFTFS+P Q K+N G+L RWTKGF GV+G+DV+ +
Sbjct: 132 AESLKDFLEEQFPEGVHQTLPLGFTFSYPASQDKINMGILQRWTKGFDIPGVEGHDVVPM 191
Query: 195 LQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDP 254
LQ + +V++ + VVAL NDT GTL++ + D E ++GVI GTG N Y++ + K
Sbjct: 192 LQESLRKVNVPIEVVALINDTTGTLVASLYTDAETKMGVIFGTGVNGAYYDVVKDIEKLE 251
Query: 255 AVAARG---SALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYL 311
+ IN E G+FD+++ VLP TK+D+ ID+ S GQQA EKM SG YL
Sbjct: 252 GRLPEDIPPESAMAINCEYGSFDNEH-LVLPRTKYDILIDEQSPRPGQQAFEKMTSGYYL 310
Query: 312 GEIARRVIVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
GE+ R ++ L + + L ++ F I D L+ T +
Sbjct: 311 GEVLRLALLDLHGQGLIFQGQDISKLETPYVMDTSFPARIEDDPFENLEETDDLFKDNLD 370
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+D E ++IR + ++ RAA+LS A + + A IA DGSVF K P F+
Sbjct: 371 IDTTRPE-RKLIRKLSEMIGNRAARLSVCGIAAI-CQKRGYETAHIAADGSVFNKYPGFQ 428
Query: 431 RVLQDNINRILGPE------CDVRAVLAKDGSGIGAAFISAMVVND 470
+ + I G E ++ V A+DGSG GAA I+A+
Sbjct: 429 TRAAEGLRDIYGWEHSSSQDYPIKIVAAEDGSGAGAAVIAALTTKR 474
>ref|XP_001381777.1| PREDICTED: similar to hexokinase II [Monodelphis domestica]
Length = 917
Score = 549 bits (1415), Expect = e-154, Method: Composition-based stats.
Identities = 166/499 (33%), Positives = 258/499 (51%), Gaps = 39/499 (7%)
Query: 2 SRRLNNILEHISI------------QGNDGETVRAV-----KRDVAMAALTNQFTMSVES 44
+ RL+ + + G V AV + A +S +
Sbjct: 424 ATRLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEALKLSYDQ 483
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ ++ + EM GL ++V+MLP+YV G F ALDLGGTNFRVL V
Sbjct: 484 LLEVKKRMKREMERGLSKETHAAASVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLV 543
Query: 102 ACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFT 159
+ G V+ + IP+ + G +LF I + +E + + ++PLGFT
Sbjct: 544 RVRNGMRRGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGV--SLPLGFT 601
Query: 160 FSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGT 218
FSFP +Q ++ +L++WTKGF G G DV+ LL+ A R ++VVA+ NDTVGT
Sbjct: 602 FSFPCQQNSLDESILLKWTKGFKATGCVGEDVVGLLKDAIHRREEFDLDVVAVVNDTVGT 661
Query: 219 LISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYR 278
+++ ++DP +VG+I+GTGSNACY E V R INME G F +
Sbjct: 662 MMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGDDGR----MCINMEWGAFGDEGC 717
Query: 279 FVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALG 337
T+FDL +D+ SLN G+Q EKMISGMYLGEI R ++++ + L + L
Sbjct: 718 LDDIRTEFDLAVDELSLNPGKQRFEKMISGMYLGEIVRNILINFTKRGLLFRGRISERLK 777
Query: 338 NRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLS 397
RG FE++F I +D + LQ R+ + + G++ + +D I+++VC +V RAAQL
Sbjct: 778 TRGIFETKFLSQIESDCLALLQ-VRTIL-RHLGLE-STCDDSIIVKEVCTVVARRAAQLC 834
Query: 398 ASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLA 452
+ A + K + + TI +DG++++ P F +V+ + + L P+CDV + +
Sbjct: 835 GAGMAAVVDKIRENRQLDSLKVTIGVDGTLYKLHPHFAKVMHETVKE-LAPKCDVSFLES 893
Query: 453 KDGSGIGAAFISAMVVNDK 471
+DGSG GAA I+A+ +
Sbjct: 894 EDGSGKGAALITAVACRIR 912
Score = 517 bits (1333), Expect = e-145, Method: Composition-based stats.
Identities = 157/458 (34%), Positives = 244/458 (53%), Gaps = 22/458 (4%)
Query: 25 VKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKR 81
+ + +S E+++++ EM +GL ++V+MLP++V
Sbjct: 16 HDQVQKVDQYLYHMRLSDETLQEVSKRFRKEMEKGLGADTHPTASVKMLPTFVRSTPDGT 75
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASNVK 139
G F ALDLGGTNFRVLRV + V+ + IP+ + G+ T LF IA +
Sbjct: 76 EDGDFLALDLGGTNFRVLRVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIADCLA 135
Query: 140 KTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAF 199
M+ + N+ +PLGFTFSFP QTK++ L+ WTKGF + GV+G DV++L++ A
Sbjct: 136 NFMDKLQIK--NKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVSLIRKAI 193
Query: 200 GRV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAA 258
R +++VA+ NDTVGT+++ + D ++G+I+GTG+NACY E +
Sbjct: 194 QRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGTNACYMEEMRYIDAVEGDEG 253
Query: 259 RGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRV 318
R INME G F T+FD +ID SLN G+Q EKMISGMY+GE+ R +
Sbjct: 254 R----MCINMEWGAFGDDGVLDDIRTEFDREIDMGSLNPGKQLFEKMISGMYMGELVRLI 309
Query: 319 IVHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+V ++ L L L G FE++ I ++ G++ + + G+ S E
Sbjct: 310 LVKMAKEEMLFGGKLSPDLLTTGRFETKDVSDIEGEK-DGIKKALDILTR-LGLQ-PSQE 366
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRV 432
D +C++V R+A L A+ A L + + R+TI +DGSV++K P F
Sbjct: 367 DCVATHRICQIVSTRSANLCAATLAAVLRRLKENKGDDRLRSTIGVDGSVYKKHPHFATR 426
Query: 433 LQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVND 470
L + R++ P+CDVR + ++DGSG GAA ++A+
Sbjct: 427 LHKAVRRLV-PDCDVRFLRSEDGSGKGAAMVTAVAYRL 463
>ref|XP_001660031.1| hexokinase [Aedes aegypti]
gb|EAT38749.1| hexokinase [Aedes aegypti]
Length = 453
Score = 548 bits (1414), Expect = e-154, Method: Composition-based stats.
Identities = 147/445 (33%), Positives = 231/445 (51%), Gaps = 9/445 (2%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGLEG---RESTVRMLPSYVYKADPKRATGVFY 87
+ + +S + + +IM LL E+ GL E+ ++ +YV + G F
Sbjct: 11 IREQCQELILSDKQIEEIMRRLLKEINRGLGKATQPEADIKCFITYVQDLPNGKEKGKFL 70
Query: 88 ALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAP 147
ALDLGGTNFRVL + K+ + + + IP+ + G+ T LF IA + M+ +
Sbjct: 71 ALDLGGTNFRVLLIHLKDENDFEMLSKIYAIPQSIMLGSGTQLFDHIAECLANFMKEHSV 130
Query: 148 EDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKV 206
+PLGFTFSFP+ Q + +G+L RWTKGF+ GV G DV+ LL+ A R +++
Sbjct: 131 --YEEKLPLGFTFSFPLTQLGLTKGILARWTKGFNCSGVVGEDVVQLLKDAIARRGDVQI 188
Query: 207 NVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPI 266
+ A+ NDT GTL+S +K+ ++G+I+GTGSNACY E I
Sbjct: 189 EICAILNDTTGTLMSCAWKNHNCRIGLIVGTGSNACYVEKVENCEMFDGPKDPKKEHVLI 248
Query: 267 NMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSIN 326
N E G F T++D +ID S+N G+Q EKMISGMY+GE+AR IV +
Sbjct: 249 NTEWGAFGDNGALDFVRTEYDREIDHFSINPGRQIQEKMISGMYMGELARLAIVKFTRAG 308
Query: 327 CLPAAL-QTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDV 385
L + L RG F +++ I +D+ + R + G++ + ED +R +
Sbjct: 309 LLFGGVGSDILFKRGQFFTKYVSEIESDKPGTYMYCRDVL-DELGLEHATDEDCANVRYI 367
Query: 386 CRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPEC 445
C V RAA L ++ A + K + T+ +DGSV+ P F +++ I + + P+
Sbjct: 368 CECVSSRAAHLVSAGIAALINKMDEKS-VTVGVDGSVYRFHPKFHDLMKAKIRQFVKPDI 426
Query: 446 DVRAVLAKDGSGIGAAFISAMVVND 470
+L++DGSG GAA ++A+ +
Sbjct: 427 SFDLMLSEDGSGRGAALVAAVACRE 451
>ref|XP_001400569.1| hexokinase hxk-Aspergillus niger
emb|CAA08922.1| hexokinase [Aspergillus niger]
emb|CAK48869.1| hexokinase hxk-Aspergillus niger
Length = 490
Score = 548 bits (1414), Expect = e-154, Method: Composition-based stats.
Identities = 150/464 (32%), Positives = 238/464 (51%), Gaps = 13/464 (2%)
Query: 17 NDGETVRAVKRDV--AMAALTNQFTMSVESMRQIMTYLLYEMVEGLEGRESTVRMLPSYV 74
+ ++ V +++ + +QFT+ ++QI+ + + E+ +GL + M ++V
Sbjct: 11 SRKGSMADVPQNLLQQIKDFEDQFTVDRSKLKQIVNHFVKELEKGLSVEGGNIPMNVTWV 70
Query: 75 YKADPKRATGVFYALDLGGTNFRVLRVAC-KEGAVVDSSTSAFKIPKYALEGNATDLFGF 133
G F ALD+GGTN RV + +E D + S +++P+ G A +L+ +
Sbjct: 71 LGFPDGDEQGTFLALDMGGTNLRVCEITLTQEKGAFDITQSKYRMPEELKTGTAEELWEY 130
Query: 134 IASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIA 193
IA +++ +E+ + +PLGFTFS+P Q ++ GVL RWTKGF GV+G+DV+
Sbjct: 131 IADCLQQFIESHHENEKISKLPLGFTFSYPATQDYIDHGVLQRWTKGFDIDGVEGHDVVP 190
Query: 194 LLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKD 253
L+A + L + V AL NDT GTLI+ + D ++++G I GTG NA Y E A ++ K
Sbjct: 191 PLEAILQKRGLPIKVAALINDTTGTLIASSYTDSDMKIGCIFGTGVNAAYMENAGSIPKL 250
Query: 254 PAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGE 313
+ IN E G FD+++ VLP TK+D ID S GQQA EKM +G+YLGE
Sbjct: 251 AHMNLPADMPVAINCEYGAFDNEH-IVLPLTKYDHIIDRDSPRPGQQAFEKMTAGLYLGE 309
Query: 314 IARRVIVHLSSI--NCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCG 370
I R ++ L + T L ++ F I D L+ T +++
Sbjct: 310 IFRLALMDLVENRPGLIFNGQDTTKLRKPYILDASFLAAIEEDPYENLEETEELMERELN 369
Query: 371 VDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDGSVFEKIPSFR 430
+ + +L +IR + L+ RAA+LSA A K + + DGSVF K P F+
Sbjct: 370 IKA-TPAELEMIRRLAELIGTRAARLSACGVAAICTKKK-IDSCHVGADGSVFTKYPHFK 427
Query: 431 RVLQDNINRILGP----ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ IL + V + A+DGSG+GAA I+A+ +
Sbjct: 428 ARGAKALREILDWAPEEQDKVTIMAAEDGSGVGAALIAALTLKR 471
>emb|CAH65327.1| hypothetical protein [Gallus gallus]
Length = 780
Score = 548 bits (1414), Expect = e-154, Method: Composition-based stats.
Identities = 163/499 (32%), Positives = 253/499 (50%), Gaps = 39/499 (7%)
Query: 2 SRRLNNILEHISI------------QGNDGETVRAV-----KRDVAMAALTNQFTMSVES 44
+RRL+ + G V AV ++ + +F ++ E
Sbjct: 287 ARRLHKTTRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLSEQHRLIDETLAEFKLTHEQ 346
Query: 45 MRQIMTYLLYEMVEGLEG---RESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ Q+ + EM GL+ + V+MLP++V G F ALDLGGTNFRVL V
Sbjct: 347 LLQVKKRMRTEMEAGLKKKSHETAKVKMLPTFVRSTPDGTENGDFLALDLGGTNFRVLLV 406
Query: 102 ACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFT 159
+ G V+ + IP ++G +LF I + + ++ + +PLGFT
Sbjct: 407 KIRSGKRRTVEMHNKIYAIPIEVMQGTGEELFDHIVTCISDFLDYMGIK--GARLPLGFT 464
Query: 160 FSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGT 218
FSFP +QT ++ G+L+ WTKGF +G DV+ LL+ R ++VVA+ NDTVGT
Sbjct: 465 FSFPCKQTSLDAGILLNWTKGFKATDCEGEDVVYLLREGIKRREEFDLDVVAVVNDTVGT 524
Query: 219 LISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYR 278
+++ ++DP ++G+I+GTGSNACY E + R +NME G F
Sbjct: 525 MMTCAYEDPNCEIGLIVGTGSNACYMEEMRNIEMVDGEQGR----MCVNMEWGAFGDNGC 580
Query: 279 FVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALG 337
T +D +DD SLN G+Q EKMISGMYLGEI R +++ + L + L
Sbjct: 581 LDDIRTIYDKAVDDYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKRGFLFRGQISETLK 640
Query: 338 NRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLS 397
R FE++F I +DR+ LQ R+ +Q+ G+ + +D I++ VC V RAAQL
Sbjct: 641 TRHIFETKFLSQIESDRLALLQ-VRTILQQ-LGL-NSTCDDSIIVKTVCGAVSKRAAQLC 697
Query: 398 ASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLA 452
+ A + K + T+ +DG++++ P F R++ + L P+CDV +L+
Sbjct: 698 GAGMVAVVDKIRENRGLEHLEITVGVDGTLYKLHPHFSRIMHQTVKD-LAPKCDVTFLLS 756
Query: 453 KDGSGIGAAFISAMVVNDK 471
+DGSG GAA I+A+ +
Sbjct: 757 EDGSGKGAALITAVGCRLR 775
Score = 359 bits (922), Expect = 3e-97, Method: Composition-based stats.
Identities = 117/327 (35%), Positives = 179/327 (54%), Gaps = 15/327 (4%)
Query: 151 NRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SLKVNVV 209
++ +P+GFTFSFP Q+K++ G+LI WTK F GV+G DV+ LL A + +++
Sbjct: 8 DKKLPVGFTFSFPCRQSKLDEGILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDADIM 67
Query: 210 ALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINME 269
A+ NDTVGT+++ F D +VG+IIGTG+NACY E + R IN E
Sbjct: 68 AVVNDTVGTMMTCGFDDQRCEVGLIIGTGTNACYMEEMRHIDLVEGDEGR----MCINTE 123
Query: 270 SGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP 329
G F T+FD +ID SLN G+Q EKM+SGMY+GE+ R ++V ++ L
Sbjct: 124 WGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKEGLLF 183
Query: 330 -AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRL 388
+ L +G FE++ I + GL + + + GV+ S ED ++ VC +
Sbjct: 184 EGRITPELLTKGKFETKHVSAIEKSK-EGLNKAKEILTR-LGVE-PSHEDCIAVQHVCTI 240
Query: 389 VRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGP 443
V R+A L AS A L + + R T+ +DGS+++ P + R L R++ P
Sbjct: 241 VSFRSANLVASTLGAILNQLRDNKGVGRLRTTVGVDGSLYKMHPQYARRLHKTTRRLV-P 299
Query: 444 ECDVRAVLAKDGSGIGAAFISAMVVND 470
+ DVR +L++ GSG GAA ++A+
Sbjct: 300 DSDVRFLLSESGSGKGAAMVTAVAYRL 326
>ref|XP_532991.2| PREDICTED: similar to hexokinase 2 [Canis familiaris]
Length = 909
Score = 548 bits (1413), Expect = e-154, Method: Composition-based stats.
Identities = 164/499 (32%), Positives = 256/499 (51%), Gaps = 39/499 (7%)
Query: 2 SRRLNNILEHISI------------QGNDGETVRAV-----KRDVAMAALTNQFTMSVES 44
++RL+ + + G V AV + A +S E
Sbjct: 416 AKRLHKTVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQNTLESLKLSREQ 475
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ ++ + EM GL + V+MLP+YV G F ALDLGGTNFRVL V
Sbjct: 476 LLEVKRRMNVEMGRGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLV 535
Query: 102 ACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFT 159
K G V+ + IP+ + G +LF I + +E + + ++PLGFT
Sbjct: 536 RVKNGKRRGVEMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGV--SLPLGFT 593
Query: 160 FSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGT 218
FSFP +Q ++ +L++WTKGF G +G DV+ LL+ A R ++VVA+ NDTVGT
Sbjct: 594 FSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGT 653
Query: 219 LISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYR 278
+++ ++DP +VG+I+GTGSNACY E V R +NME G F
Sbjct: 654 MMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR----MCVNMEWGAFGDNGC 709
Query: 279 FVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALG 337
T+FD+ +D+ SLN G+Q EKMISGMYLGEI R +++ + L + L
Sbjct: 710 LDDIRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLK 769
Query: 338 NRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLS 397
RG FE++F I +D + LQ R+ + G++ + +D I+++VC +V RAAQL
Sbjct: 770 TRGIFETKFLSQIESDCLALLQ-VRAIL-HHLGLE-STCDDSIIVKEVCTVVARRAAQLC 826
Query: 398 ASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLA 452
+ A + K + + T+ +DG++++ P F +++ + + L P+CDV + +
Sbjct: 827 GAGMAAVVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKIMHETVKD-LAPKCDVSFLES 885
Query: 453 KDGSGIGAAFISAMVVNDK 471
+DGSG GAA I+A+ +
Sbjct: 886 EDGSGKGAALITAVACRIR 904
Score = 517 bits (1333), Expect = e-145, Method: Composition-based stats.
Identities = 161/452 (35%), Positives = 244/452 (53%), Gaps = 22/452 (4%)
Query: 31 MAALTNQFTMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKRATGVFY 87
+ +S E++ +I EM +GL ++V+MLP++V G F
Sbjct: 14 VDQYLYHMRLSDENLLEISKRFRKEMEKGLGATTHPTASVKMLPTFVRSTPDGTEHGEFL 73
Query: 88 ALDLGGTNFRVLRVACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETR 145
ALDLGGTNFRVLRV + V+ + IP+ + G+ T LF IA + M+
Sbjct: 74 ALDLGGTNFRVLRVRVTDNGLQKVEMENQIYAIPEDLMRGSGTQLFDHIAECLANFMDKL 133
Query: 146 APEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRV-SL 204
+D + +PLGFTFSFP QTK++ L+ WTKGF + GV+G DV+ L++ A R
Sbjct: 134 QIKD--KKLPLGFTFSFPCVQTKLDESFLVSWTKGFKSSGVEGKDVVTLIRKAIQRRGDF 191
Query: 205 KVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALT 264
+++VA+ NDTVGT+++ + D ++G+I+GTGSNACY E + R
Sbjct: 192 DIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGR----M 247
Query: 265 PINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSS 324
INME G F T+FD +ID SLN G+Q EKMISGMY+GE+ R ++V ++
Sbjct: 248 CINMEWGAFGDDGILDDFRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAK 307
Query: 325 INCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIR 383
L L L G FE++ I ++ G++ R + + G+D + ED
Sbjct: 308 EELLFGGKLSPGLLATGQFETKDVSDIEGEK-DGIRKAREVLVR-LGID-PTQEDCVATH 364
Query: 384 DVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNIN 438
VC++V R+A L A+ A L + + R+TI +DGSV++K P F + L +
Sbjct: 365 RVCQIVSTRSASLCAATLAAVLRRIKENKGEERLRSTIGVDGSVYKKHPHFAKRLHKTVR 424
Query: 439 RILGPECDVRAVLAKDGSGIGAAFISAMVVND 470
R++ P+CDVR + ++DGSG GAA ++A+
Sbjct: 425 RLV-PDCDVRFLRSEDGSGKGAAMVTAVAYRL 455
>dbj|BAF83046.1| unnamed protein product [Homo sapiens]
Length = 917
Score = 548 bits (1413), Expect = e-154, Method: Composition-based stats.
Identities = 164/499 (32%), Positives = 257/499 (51%), Gaps = 39/499 (7%)
Query: 2 SRRLNNILEHISI------------QGNDGETVRAV-----KRDVAMAALTNQFTMSVES 44
++RL+ + + G V AV + A +S +
Sbjct: 424 AKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLSHDQ 483
Query: 45 MRQIMTYLLYEMVEGLEGR---ESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ ++ + EM GL + V+MLP+YV G F ALDLGGTNFRVL V
Sbjct: 484 LLEVKRRMKVEMERGLSKETHAGAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLV 543
Query: 102 ACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFT 159
+ G V+ + IP+ + G +LF I + +E + + ++PLGFT
Sbjct: 544 RVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGV--SLPLGFT 601
Query: 160 FSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGT 218
FSFP +Q ++ +L++WTKGF G +G DV+ LL+ A R ++VVA+ NDTVGT
Sbjct: 602 FSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGT 661
Query: 219 LISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYR 278
+++ F+DP +VG+I+GTGSNACY E V R +NME G F
Sbjct: 662 MMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR----MCVNMEWGAFGDNGC 717
Query: 279 FVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALG 337
T+FD+ +D+ SLN G+Q EKMISGMYLGEI R +++ + L + L
Sbjct: 718 LDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLK 777
Query: 338 NRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLS 397
RG FE++F I +D + LQ R+ +Q G++ + +D I+++VC +V RAAQL
Sbjct: 778 TRGIFETKFLSQIESDCLALLQ-VRAILQ-HLGLE-STCDDSIIVKEVCTVVARRAAQLC 834
Query: 398 ASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLA 452
+ A + + + + T+ +DG++++ P F +V+ + + L P+CDV + +
Sbjct: 835 GAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKD-LAPKCDVSFLQS 893
Query: 453 KDGSGIGAAFISAMVVNDK 471
+DGSG GAA I+A+ +
Sbjct: 894 EDGSGKGAALITAVACRIR 912
Score = 520 bits (1340), Expect = e-145, Method: Composition-based stats.
Identities = 161/458 (35%), Positives = 244/458 (53%), Gaps = 22/458 (4%)
Query: 25 VKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKR 81
+ + +S E++ +I EM +GL + V+MLP++V
Sbjct: 16 HDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGT 75
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASNVK 139
G F ALDLGGTNFRVL V + V+ + IP+ + G+ T LF IA +
Sbjct: 76 EHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLA 135
Query: 140 KTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAF 199
M+ +D + +PLGFTFSFP QTK++ L+ WTKGF + GV+G DV+AL++ A
Sbjct: 136 NFMDKLHIKD--KKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAI 193
Query: 200 GRV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAA 258
R +++VA+ NDTVGT+++ + D ++G+I+GTGSNACY E +
Sbjct: 194 QRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEG 253
Query: 259 RGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRV 318
R INME G F T+FD +ID SLN G+Q EKMISGMY+GE+ R +
Sbjct: 254 R----MCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLI 309
Query: 319 IVHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+V ++ L L L N G FE++ I ++ G++ R + + G+D + E
Sbjct: 310 LVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEK-DGIRKAREVLMR-LGLD-PTQE 366
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRV 432
D +C++V R+A L A+ A L + + R+TI +DGSV++K P F +
Sbjct: 367 DCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKR 426
Query: 433 LQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVND 470
L + R++ P CDVR + ++DGSG GAA ++A+
Sbjct: 427 LHKTVRRLV-PGCDVRFLRSEDGSGKGAAMVTAVAYRL 463
>gb|AAA41334.1| hexokinase type II
Length = 516
Score = 548 bits (1413), Expect = e-154, Method: Composition-based stats.
Identities = 164/499 (32%), Positives = 258/499 (51%), Gaps = 39/499 (7%)
Query: 2 SRRLNNILEHISI------------QGNDGETVRAV-----KRDVAMAALTNQFTMSVES 44
++RL+ + + G V AV + A +S E
Sbjct: 23 AKRLHKAVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLESLKLSHEQ 82
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ ++ + EM +GL + V+MLP+YV G F ALDLGGTNFRVL V
Sbjct: 83 LLEVKRRMKVEMEQGLSKETHAVAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLV 142
Query: 102 ACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFT 159
+ G V+ + IP+ + G +LF I + +E + + ++PLGFT
Sbjct: 143 RVRNGKRRGVEMHNKIYSIPQEVMHGTGEELFDHIVQCIADFLEYMGMKGV--SLPLGFT 200
Query: 160 FSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGT 218
FSFP +Q +++ +L++WTKGF G +G DV+ LL+ A R ++VVA+ NDTVGT
Sbjct: 201 FSFPCQQNSLDQSILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGT 260
Query: 219 LISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYR 278
+++ ++DP +VG+I+GTGSNACY E V R +NME G F
Sbjct: 261 MMTCGYEDPHCEVGLIVGTGSNACYMEEMRNVELVDGEEGR----MCVNMEWGAFGDNGC 316
Query: 279 FVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALG 337
T FD+ +D+ SLN G+Q EKMISGMYLGEI R +++ + L + L
Sbjct: 317 LDDLRTVFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLK 376
Query: 338 NRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLS 397
RG FE++F I +D + LQ R+ + + G++ + +D I+++VC +V RAAQL
Sbjct: 377 TRGIFETKFLSQIESDCLALLQ-VRAIL-RHLGLE-STCDDSIIVKEVCTVVARRAAQLC 433
Query: 398 ASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLA 452
+ A + K + + T+ +DG++++ P F +V+ + + L P+CDV + +
Sbjct: 434 GAGMAAVVDKIRENRGLDNLKVTVGVDGTLYKLHPHFAKVMHETVRD-LAPKCDVSFLES 492
Query: 453 KDGSGIGAAFISAMVVNDK 471
+DGSG GAA I+A+ +
Sbjct: 493 EDGSGKGAALITAVACRIR 511
Score = 79.4 bits (195), Expect = 5e-13, Method: Composition-based stats.
Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 409 QTQGRATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVV 468
+ + R+TI +DGSV++K P F + L + R++ P+CDVR + ++DGSG GAA ++A+
Sbjct: 2 EERLRSTIGVDGSVYKKHPHFAKRLHKAVRRLV-PDCDVRFLRSEDGSGKGAAMVTAVAY 60
Query: 469 ND 470
Sbjct: 61 RL 62
>ref|XP_816463.1| hexokinase, putative [Trypanosoma cruzi strain CL Brener]
gb|EAN94612.1| hexokinase, putative [Trypanosoma cruzi]
Length = 471
Score = 548 bits (1412), Expect = e-154, Method: Composition-based stats.
Identities = 316/471 (67%), Positives = 385/471 (81%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MS RLNN+L+HI+++ D +T+R +K+ +A+A+L NQFT+ + ++Q+M Y+++EM+EGL
Sbjct: 1 MSARLNNLLQHIAVKDKDSDTMRHLKQRMALASLANQFTVGKDHLKQLMLYMVHEMIEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGREST+RMLPSYVYK DP +ATGVFYALDLGGTNFRVLRV CKEG V D + F IP+
Sbjct: 61 EGRESTLRMLPSYVYKTDPSKATGVFYALDLGGTNFRVLRVTCKEGRVADRVDAKFVIPQ 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
AL+G A DLFGFIA +VKK ME +APEDLNRTVPLGFTFSFP EQ V+ G LI+WTKG
Sbjct: 121 QALQGTAEDLFGFIAQSVKKMMEQKAPEDLNRTVPLGFTFSFPTEQKGVDHGFLIKWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FST+GV+G DV+ LLQ A R+ +KV VVALCNDTVGTLI++YF DP+ QVGVIIGTGSN
Sbjct: 181 FSTRGVEGKDVVELLQKALKRMEVKVKVVALCNDTVGTLITNYFFDPDTQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFE A AVTK+P+VAARG+ TPINME GNFDSKY+FVLP T +D +D + N+ Q
Sbjct: 241 ACYFEDAYAVTKEPSVAARGTTQTPINMECGNFDSKYKFVLPVTAYDEAMDAVTPNRNYQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
EKM+SGMYLGEI+RR+I HL+ ++CLP+AL + + SFE++F GMISADRMPGLQF
Sbjct: 301 TQEKMVSGMYLGEISRRMIAHLAELHCLPSALASKMAKPWSFETKFMGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TR Q++ VDV + DL +IRDVC LVRGRAAQ+SA FC APLVKT+ +GRAT+AIDG
Sbjct: 361 TRQVFQELFHVDVTDVADLHVIRDVCCLVRGRAAQISAMFCSAPLVKTRKEGRATVAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEK PSFRR+LQ N+N ILGP CDV LA+DGSGIGAAFISA+VVNDK
Sbjct: 421 SVFEKTPSFRRLLQQNMNAILGPGCDVTTALARDGSGIGAAFISALVVNDK 471
>gb|AAY24209.1| unknown [Homo sapiens]
Length = 573
Score = 548 bits (1412), Expect = e-154, Method: Composition-based stats.
Identities = 164/499 (32%), Positives = 257/499 (51%), Gaps = 39/499 (7%)
Query: 2 SRRLNNILEHISI------------QGNDGETVRAV-----KRDVAMAALTNQFTMSVES 44
++RL+ + + G V AV + A +S +
Sbjct: 80 AKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLSHDQ 139
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ ++ + EM GL + V+MLP+YV G F ALDLGGTNFRVL V
Sbjct: 140 LLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLV 199
Query: 102 ACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFT 159
+ G V+ + IP+ + G +LF I + +E + + ++PLGFT
Sbjct: 200 RVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGV--SLPLGFT 257
Query: 160 FSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGT 218
FSFP +Q ++ +L++WTKGF G +G DV+ LL+ A R ++VVA+ NDTVGT
Sbjct: 258 FSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGT 317
Query: 219 LISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYR 278
+++ F+DP +VG+I+GTGSNACY E V R +NME G F
Sbjct: 318 MMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR----MCVNMEWGAFGDNGC 373
Query: 279 FVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALG 337
T+FD+ +D+ SLN G+Q EKMISGMYLGEI R +++ + L + L
Sbjct: 374 LDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLK 433
Query: 338 NRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLS 397
RG FE++F I +D + LQ R+ +Q G++ + +D I+++VC +V RAAQL
Sbjct: 434 TRGIFETKFLSQIESDCLALLQ-VRAILQ-HLGLE-STCDDSIIVKEVCTVVARRAAQLC 490
Query: 398 ASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLA 452
+ A + + + + T+ +DG++++ P F +V+ + + L P+CDV + +
Sbjct: 491 GAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKD-LAPKCDVSFLQS 549
Query: 453 KDGSGIGAAFISAMVVNDK 471
+DGSG GAA I+A+ +
Sbjct: 550 EDGSGKGAALITAVACRIR 568
Score = 120 bits (301), Expect = 3e-25, Method: Composition-based stats.
Identities = 39/120 (32%), Positives = 66/120 (55%), Gaps = 8/120 (6%)
Query: 356 PGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG--- 412
G++ R + + G+D + ED +C++V R+A L A+ A L + +
Sbjct: 3 DGIRKAREVLMR-LGLD-PTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEE 60
Query: 413 --RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVND 470
R+TI +DGSV++K P F + L + R++ P CDVR + ++DGSG GAA ++A+
Sbjct: 61 RLRSTIGVDGSVYKKHPHFAKRLHKTVRRLV-PGCDVRFLRSEDGSGKGAAMVTAVAYRL 119
>ref|NP_989543.1| hexokinase 2 [Gallus gallus]
dbj|BAC20933.1| hexokinase2 [Gallus gallus]
Length = 916
Score = 548 bits (1412), Expect = e-154, Method: Composition-based stats.
Identities = 172/499 (34%), Positives = 264/499 (52%), Gaps = 39/499 (7%)
Query: 2 SRRLNNILEHISI------------QGNDGETVRAVK-----RDVAMAALTNQFTMSVES 44
+RRL+ + + G V AV + A + +S E
Sbjct: 424 ARRLHKTVRKLLPDCEIRFVRSEDGSGKGAAMVTAVAYRLAAQHKARQKILEALKLSHEQ 483
Query: 45 MRQIMTYLLYEMVEGLEGR---ESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ ++ + EM +GL E+TV+MLP+YV G F ALDLGGTNFRVL V
Sbjct: 484 LLEVKRRMRVEMEKGLGKETHAEATVKMLPTYVCSTPDGTEKGDFLALDLGGTNFRVLLV 543
Query: 102 ACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFT 159
+ G V+ + IP ++G +LF I + +E + + ++PLGFT
Sbjct: 544 RVRNGMRRGVEMHNKIYSIPLEVMQGTGEELFDHIVHCISDFLEYMGMKGV--SLPLGFT 601
Query: 160 FSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGT 218
FSFP +QT ++ G+L++WTKGF G +G DV++LL+ A R ++VVA+ NDTVGT
Sbjct: 602 FSFPCKQTNLDEGILLKWTKGFKATGCEGEDVVSLLKEAIHRREEFDLDVVAVVNDTVGT 661
Query: 219 LISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYR 278
+++ ++DP +VG+I+GTGSNACY E V R +NME G F
Sbjct: 662 MMTCGYEDPYCEVGLIVGTGSNACYMEEMRNVELVEGDEGR----MCVNMEWGAFGDNGC 717
Query: 279 FVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALG 337
T+FDL +D+ SLN G+Q EKMISGMYLGEI R +++ + L + L
Sbjct: 718 LDDIQTEFDLAVDELSLNPGKQRFEKMISGMYLGEIVRNILMDFTKRGLLFRGRISERLK 777
Query: 338 NRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLS 397
RG FE++F I +D + LQ RS +Q G++ + +D I+++VC +V RAAQL
Sbjct: 778 TRGIFETKFLSQIESDCLALLQ-VRSILQ-HLGLE-STCDDSIIVKEVCTVVARRAAQLC 834
Query: 398 ASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLA 452
+ A + K + + T+ +DG++++ P F ++QD + + L P C+V + +
Sbjct: 835 GAGMAAVVDKIRENRGLDFLKVTVGVDGTLYKLHPHFSAIMQDTVRQ-LSPCCEVTFLQS 893
Query: 453 KDGSGIGAAFISAMVVNDK 471
+DGSG GAA I+A+ +
Sbjct: 894 EDGSGKGAALITAVACRIR 912
Score = 520 bits (1339), Expect = e-145, Method: Composition-based stats.
Identities = 160/458 (34%), Positives = 246/458 (53%), Gaps = 22/458 (4%)
Query: 25 VKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKR 81
+ + +S ++++++ EM +GL ++V+MLPS+V
Sbjct: 16 HDQAQKVDKYLYHMRLSEDTLQEVSERFRKEMEKGLGADTNPTASVKMLPSFVRSTPDGT 75
Query: 82 ATGVFYALDLGGTNFRVLRVACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASNVK 139
G F ALDLGGTNFRVLRV + V+ + ++I + + G+ LF IA +
Sbjct: 76 EDGDFLALDLGGTNFRVLRVKVSDNGLQKVEMESQIYEIHEDLMRGSGMQLFDHIAECLG 135
Query: 140 KTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAF 199
ME +D + +PLGFTFSFP QTK++ +L+ WTKGF V+G DV++LL+ A
Sbjct: 136 NFMEKLKIKD--KKLPLGFTFSFPCHQTKLDESILVNWTKGFKCSSVEGKDVVSLLRRAI 193
Query: 200 GRV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAA 258
+ +++VA+ NDTVGT++S + D +VG+I+GTG+NACY E +
Sbjct: 194 KKRGDFDIDIVAVVNDTVGTMMSCGYDDQNCEVGLIVGTGTNACYMEEMRHIDLVEGDEG 253
Query: 259 RGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRV 318
R INME G F T+FD +ID SLN G+Q EKMISGMY+GE+ R +
Sbjct: 254 R----MCINMEWGAFGDDGALNDIRTEFDHEIDMGSLNPGKQLFEKMISGMYMGELVRLI 309
Query: 319 IVHLSSINCLP-AALQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIE 377
+V ++ L L + L G FE+RF I ++ GLQ + K G++ S E
Sbjct: 310 LVKMAKEGLLFQGKLSSDLRTTGHFETRFVSAIEKEK-EGLQKAHEILTK-LGLE-PSHE 366
Query: 378 DLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRV 432
D +C++V R+A L + A L + + R+T+ +DGSV++K P F R
Sbjct: 367 DCLATHRICQIVSTRSANLCGATLAARLRRIKEYKGVDPLRSTVGVDGSVYKKYPHFARR 426
Query: 433 LQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVND 470
L + ++L P+C++R V ++DGSG GAA ++A+
Sbjct: 427 LHKTVRKLL-PDCEIRFVRSEDGSGKGAAMVTAVAYRL 463
>pdb|2NZT|A Chain A, Crystal Structure Of Human Hexokinase Ii
pdb|2NZT|B Chain B, Crystal Structure Of Human Hexokinase Ii
Length = 902
Score = 548 bits (1412), Expect = e-154, Method: Composition-based stats.
Identities = 164/499 (32%), Positives = 257/499 (51%), Gaps = 39/499 (7%)
Query: 2 SRRLNNILEHISI------------QGNDGETVRAV-----KRDVAMAALTNQFTMSVES 44
++RL+ + + G V AV + A +S +
Sbjct: 410 AKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLSHDQ 469
Query: 45 MRQIMTYLLYEMVEGLEGRE---STVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRV 101
+ ++ + EM GL + V+MLP+YV G F ALDLGGTNFRVL V
Sbjct: 470 LLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRVLLV 529
Query: 102 ACKEG--AVVDSSTSAFKIPKYALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFT 159
+ G V+ + IP+ + G +LF I + +E + + ++PLGFT
Sbjct: 530 RVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGV--SLPLGFT 587
Query: 160 FSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFGRVS-LKVNVVALCNDTVGT 218
FSFP +Q ++ +L++WTKGF G +G DV+ LL+ A R ++VVA+ NDTVGT
Sbjct: 588 FSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVGT 647
Query: 219 LISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYR 278
+++ F+DP +VG+I+GTGSNACY E V R +NME G F
Sbjct: 648 MMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGR----MCVNMEWGAFGDNGC 703
Query: 279 FVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVIVHLSSINCLP-AALQTALG 337
T+FD+ +D+ SLN G+Q EKMISGMYLGEI R +++ + L + L
Sbjct: 704 LDDFRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLK 763
Query: 338 NRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLS 397
RG FE++F I +D + LQ R+ +Q G++ + +D I+++VC +V RAAQL
Sbjct: 764 TRGIFETKFLSQIESDCLALLQ-VRAILQ-HLGLE-STCDDSIIVKEVCTVVARRAAQLC 820
Query: 398 ASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVLQDNINRILGPECDVRAVLA 452
+ A + + + + T+ +DG++++ P F +V+ + + L P+CDV + +
Sbjct: 821 GAGMAAVVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKD-LAPKCDVSFLQS 879
Query: 453 KDGSGIGAAFISAMVVNDK 471
+DGSG GAA I+A+ +
Sbjct: 880 EDGSGKGAALITAVACRIR 898
Score = 518 bits (1335), Expect = e-145, Method: Composition-based stats.
Identities = 161/457 (35%), Positives = 244/457 (53%), Gaps = 22/457 (4%)
Query: 26 KRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL---EGRESTVRMLPSYVYKADPKRA 82
+ + +S E++ +I EM +GL + V+MLP++V
Sbjct: 3 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 62
Query: 83 TGVFYALDLGGTNFRVLRVACKEGA--VVDSSTSAFKIPKYALEGNATDLFGFIASNVKK 140
G F ALDLGGTNFRVL V + V+ + IP+ + G+ T LF IA +
Sbjct: 63 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 122
Query: 141 TMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKGFSTKGVQGNDVIALLQAAFG 200
M+ +D + +PLGFTFSFP QTK++ L+ WTKGF + GV+G DV+AL++ A
Sbjct: 123 FMDKLQIKD--KKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVALIRKAIQ 180
Query: 201 RV-SLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSNACYFETASAVTKDPAVAAR 259
R +++VA+ NDTVGT+++ + D ++G+I+GTGSNACY E + R
Sbjct: 181 RRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGR 240
Query: 260 GSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQALEKMISGMYLGEIARRVI 319
INME G F T+FD +ID SLN G+Q EKMISGMY+GE+ R ++
Sbjct: 241 ----MCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGMYMGELVRLIL 296
Query: 320 VHLSSINCLPAA-LQTALGNRGSFESRFAGMISADRMPGLQFTRSTIQKVCGVDVQSIED 378
V ++ L L L N G FE++ I ++ G++ R + + G+D + ED
Sbjct: 297 VKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEK-DGIRKAREVLMR-LGLD-PTQED 353
Query: 379 LRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQG-----RATIAIDGSVFEKIPSFRRVL 433
+C++V R+A L A+ A L + + R+TI +DGSV++K P F + L
Sbjct: 354 CVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKHPHFAKRL 413
Query: 434 QDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVND 470
+ R++ P CDVR + ++DGSG GAA ++A+
Sbjct: 414 HKTVRRLV-PGCDVRFLRSEDGSGKGAAMVTAVAYRL 449
>ref|XP_822457.1| hexokinase [Trypanosoma brucei TREU927]
gb|EAN77629.1| hexokinase [Trypanosoma brucei]
Length = 471
Score = 548 bits (1412), Expect = e-154, Method: Composition-based stats.
Identities = 460/471 (97%), Positives = 465/471 (98%)
Query: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL
Sbjct: 1 MSRRLNNILEHISIQGNDGETVRAVKRDVAMAALTNQFTMSVESMRQIMTYLLYEMVEGL 60
Query: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK
Sbjct: 61 EGRESTVRMLPSYVYKADPKRATGVFYALDLGGTNFRVLRVACKEGAVVDSSTSAFKIPK 120
Query: 121 YALEGNATDLFGFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
YALEGNATDLF FIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG
Sbjct: 121 YALEGNATDLFDFIASNVKKTMETRAPEDLNRTVPLGFTFSFPVEQTKVNRGVLIRWTKG 180
Query: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVGTLISHYFKDPEVQVGVIIGTGSN 240
FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTV T+ISHYFKDPEVQVGVIIGTGSN
Sbjct: 181 FSTKGVQGNDVIALLQAAFGRVSLKVNVVALCNDTVATMISHYFKDPEVQVGVIIGTGSN 240
Query: 241 ACYFETASAVTKDPAVAARGSALTPINMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
ACYFETASAVTKDPAVAARGSALTPI+MESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ
Sbjct: 241 ACYFETASAVTKDPAVAARGSALTPISMESGNFDSKYRFVLPTTKFDLDIDDASLNKGQQ 300
Query: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF
Sbjct: 301 ALEKMISGMYLGEIARRVIVHLSSINCLPAALQTALGNRGSFESRFAGMISADRMPGLQF 360
Query: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG
Sbjct: 361 TRSTIQKVCGVDVQSIEDLRIIRDVCRLVRGRAAQLSASFCCAPLVKTQTQGRATIAIDG 420
Query: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKDGSGIGAAFISAMVVNDK 471
SVFEKIPSFRRVLQDNINRILGPECDVRAVLAK GSG+GAA ISA+V + K
Sbjct: 421 SVFEKIPSFRRVLQDNINRILGPECDVRAVLAKGGSGVGAALISAIVADGK 471
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.316 0.164 0.443
Lambda K H
0.267 0.0501 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,599,543,751
Number of Sequences: 6899187
Number of extensions: 302971532
Number of successful extensions: 863378
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 1992
Number of HSP's successfully gapped in prelim test: 215
Number of HSP's that attempted gapping in prelim test: 845797
Number of HSP's gapped (non-prelim): 2987
length of query: 471
length of database: 2,350,152,223
effective HSP length: 138
effective length of query: 333
effective length of database: 1,398,064,417
effective search space: 465555450861
effective search space used: 465555450861
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.3 bits)
S2: 81 (35.5 bits)