BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= YDR234W__[Saccharomyces_cerevisiae]
         (693 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           6,899,187 sequences; 2,350,152,223 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|NP_010520.1|  Homoaconitase, catalyzes the conversion of...  1389   0.0  
gb|AAU09698.1|  YDR234W [Saccharomyces cerevisiae]               1388   0.0  
gb|EDN60567.1|  homoaconitase [Saccharomyces cerevisiae YJM789]  1377   0.0  
ref|XP_452878.1|  unnamed protein product [Kluyveromyces lac...  1130   0.0  
ref|XP_448693.1|  unnamed protein product [Candida glabrata]...  1077   0.0  
ref|XP_001646008.1|  hypothetical protein Kpol_1031p57 [Vand...  1041   0.0  
ref|XP_001383888.2|  homoaconitase [Pichia stipitis CBS 6054...   983   0.0  
ref|XP_001485749.1|  hypothetical protein PGUG_01420 [Pichia...   968   0.0  
ref|XP_717326.1|  homoaconitase [Candida albicans SC5314] >g...   965   0.0  
sp|Q2HZ33|LYS4_CANPA  Homoaconitase, mitochondrial precursor...   963   0.0  
ref|XP_503471.1|  hypothetical protein [Yarrowia lipolytica]...   962   0.0  
ref|XP_460673.1|  hypothetical protein DEHA0F08019g [Debaryo...   955   0.0  
ref|XP_001523113.1|  homoaconitase, mitochondrial precursor ...   937   0.0  
ref|NP_982841.1|  ABL106Cp [Ashbya gossypii ATCC 10895] >gi|...   887   0.0  
ref|NP_593437.1|  homoaconitate hydratase Lys2 [Schizosaccha...   828   0.0  
ref|XP_664125.1|  LYS4_EMENI Homoaconitase, mitochondrial pr...   811   0.0  
ref|XP_001911427.1|  unnamed protein product [Podospora anse...   810   0.0  
sp|Q92412|LYS4_EMENI  Homoaconitase, mitochondrial precursor...   806   0.0  
ref|XP_001248868.1|  hypothetical protein CIMG_02639 [Coccid...   802   0.0  
ref|XP_958836.1|  homoaconitase, mitochondrial precursor [Ne...   801   0.0  
ref|XP_359935.2|  hypothetical protein MGG_04842 [Magnaporth...   800   0.0  
ref|XP_001822935.1|  hypothetical protein [Aspergillus oryza...   799   0.0  
ref|XP_001791786.1|  hypothetical protein SNOG_01131 [Phaeos...   799   0.0  
ref|XP_001396574.1|  hypothetical protein An15g00350 [Asperg...   795   0.0  
gb|EEH41326.1|  homoaconitase [Paracoccidioides brasiliensis...   794   0.0  
gb|EEH50136.1|  homoaconitase [Paracoccidioides brasiliensis...   793   0.0  
gb|ABY84678.1|  homoaconitase [Penicillium chrysogenum]           792   0.0  
ref|XP_391125.1|  hypothetical protein FG10949.1 [Gibberella...   788   0.0  
ref|XP_001228555.1|  hypothetical protein CHGG_10628 [Chaeto...   787   0.0  
ref|XP_001547913.1|  hypothetical protein BC1G_13341 [Botryo...   785   0.0  
gb|EDU46563.1|  homoaconitase, mitochondrial precursor [Pyre...   785   0.0  
ref|XP_001598937.1|  hypothetical protein SS1G_01026 [Sclero...   780   0.0  
ref|XP_001539249.1|  homoaconitase, mitochondrial precursor ...   780   0.0  
ref|XP_753748.1|  homoaconitase LysF [Aspergillus fumigatus ...   766   0.0  
gb|EDP51631.1|  homoaconitase LysF [Aspergillus fumigatus A1...   764   0.0  
emb|CAC48042.1|  homoaconitase [Aspergillus fumigatus]            764   0.0  
ref|XP_001274165.1|  homoaconitase LysF [Aspergillus clavatu...   763   0.0  
ref|XP_001259799.1|  homoaconitase LysF [Neosartorya fischer...   761   0.0  
ref|XP_001214855.1|  homoaconitase, mitochondrial precursor ...   754   0.0  
emb|CAA89720.1|  unknown [Saccharomyces cerevisiae]               729   0.0  
ref|XP_001836222.1|  hypothetical protein CC1G_06307 [Coprin...   712   0.0  
ref|XP_001880880.1|  predicted protein [Laccaria bicolor S23...   696   0.0  
ref|XP_567622.1|  homoaconitate hydratase [Cryptococcus neof...   678   0.0  
ref|XP_001729754.1|  hypothetical protein MGL_3298 [Malassez...   677   0.0  
ref|XP_772920.1|  hypothetical protein CNBK2910 [Cryptococcu...   676   0.0  
emb|CAA88513.1|  unknown [Saccharomyces cerevisiae]               675   0.0  
ref|XP_760939.1|  hypothetical protein UM04792.1 [Ustilago m...   663   0.0  
ref|YP_592040.1|  homoaconitase [Acidobacteria bacterium Ell...   608   e-172
ref|XP_001745751.1|  predicted protein [Monosiga brevicollis...   568   e-160
ref|XP_001224986.1|  hypothetical protein CHGG_07330 [Chaeto...   300   2e-79
ref|ZP_03928982.1|  3-isopropylmalate dehydratase [Acidamino...   263   6e-68
ref|ZP_02868335.1|  hypothetical protein CLOSPI_02177 [Clost...   262   6e-68
ref|YP_023690.1|  3-isopropylmalate dehydratase large subuni...   256   7e-66
ref|YP_001389789.1|  aconitase/isopropylmalate dehydratase f...   254   2e-65
ref|YP_001780072.1|  aconitase/isopropylmalate dehydratase f...   254   2e-65
ref|YP_002802745.1|  aconitase/isopropylmalate dehydratase f...   254   2e-65
ref|ZP_02429558.1|  hypothetical protein CLORAM_02981 [Clost...   254   3e-65
ref|YP_001382802.1|  aconitase/isopropylmalate dehydratase f...   253   4e-65
ref|ZP_03903264.1|  3-isopropylmalate dehydratase, large sub...   253   4e-65
ref|ZP_02612428.1|  aconitase/isopropylmalate dehydratase fa...   253   5e-65
ref|YP_001252962.1|  aconitate hydratase [Clostridium botuli...   252   9e-65
ref|ZP_02060515.1|  homoaconitate hydratase family protein [...   251   2e-64
ref|YP_001785758.1|  aconitase/isopropylmalate dehydratase f...   249   5e-64
emb|CAJ73691.1|  similar to 3-isopropylmalate dehydratase, l...   248   9e-64
ref|NP_213641.1|  3-isopropylmalate dehydratase large subuni...   248   1e-63
ref|ZP_03990811.1|  3-isopropylmalate dehydratase [Oribacter...   248   1e-63
ref|ZP_02178221.1|  3-isopropylmalate dehydratase [Hydrogeni...   246   3e-63
ref|ZP_01665133.1|  3-isopropylmalate dehydratase, large sub...   246   4e-63
ref|ZP_02615951.1|  aconitase/isopropylmalate dehydratase fa...   246   4e-63
ref|YP_001394364.1|  Aconitase-related protein [Clostridium ...   245   9e-63
ref|ZP_02421810.1|  hypothetical protein EUBSIR_00641 [Eubac...   245   9e-63
ref|YP_001884383.1|  putative aconitate hydratase [Clostridi...   245   1e-62
ref|YP_001919567.1|  putative aconitate hydratase [Clostridi...   243   3e-62
ref|NP_347607.1|  aconitate hydratase [Clostridium acetobuty...   242   7e-62
ref|YP_843415.1|  homoaconitate hydratase family protein [Me...   242   9e-62
ref|NP_578667.1|  3-isopropylmalate dehydratase large subuni...   242   1e-61
ref|YP_001435671.1|  3-isopropylmalate dehydratase [Ignicocc...   241   1e-61
ref|NP_127025.1|  3-isopropylmalate dehydratase large subuni...   241   2e-61
ref|YP_001930671.1|  homoaconitate hydratase family protein ...   241   2e-61
ref|ZP_02951252.1|  putative aconitate hydratase [Clostridiu...   240   2e-61
ref|ZP_00533649.1|  Aconitate hydratase, C-terminal:Aconitat...   239   4e-61
ref|YP_001113673.1|  homoaconitate hydratase family protein ...   239   4e-61
ref|YP_001717180.1|  homoaconitate hydratase family protein ...   239   5e-61
gb|ABC88408.1|  2,3-dimethylmalate dehydratase large subunit...   239   5e-61
ref|NP_228103.1|  3-isopropylmalate dehydratase large subuni...   239   5e-61
ref|NP_276743.1|  3-isopropylmalate dehydratase, LeuC subuni...   239   7e-61
ref|YP_001738682.1|  3-isopropylmalate dehydratase [Thermoto...   239   7e-61
ref|YP_001244217.1|  3-isopropylmalate dehydratase large sub...   239   7e-61
ref|YP_001568720.1|  homoaconitate hydratase family protein ...   238   1e-60
ref|YP_389708.1|  3-isopropylmalate dehydratase, large subun...   238   1e-60
ref|YP_001307216.1|  aconitate hydratase [Clostridium beijer...   238   1e-60
ref|NP_616329.1|  3-isopropylmalate dehydratase [Methanosarc...   238   1e-60
ref|ZP_01576278.1|  putative aconitate hydratase [Clostridiu...   238   1e-60
ref|YP_001213069.1|  3-isopropylmalate dehydratase large sub...   237   3e-60
ref|ZP_02203259.1|  3-isopropylmalate dehydratase, large sub...   237   3e-60
gb|EEJ79007.1|  aconitase [Anaerococcus prevotii DSM 20548]       237   3e-60
ref|YP_448499.1|  LeuC1 [Methanosphaera stadtmanae DSM 3091]...   237   3e-60
ref|ZP_02423106.1|  hypothetical protein EUBSIR_01964 [Eubac...   236   5e-60
ref|ZP_02993983.1|  hypothetical protein CLOSPO_01101 [Clost...   236   5e-60
ref|YP_305675.1|  3-isopropylmalate dehydratase [Methanosarc...   236   7e-60
ref|YP_001395542.1|  LeuC [Clostridium kluyveri DSM 555] >gi...   235   8e-60
ref|YP_001039546.1|  aconitate hydratase [Clostridium thermo...   235   9e-60
ref|NP_071024.1|  3-isopropylmalate dehydratase large subuni...   235   9e-60
ref|YP_181555.1|  3-isopropylmalate dehydratase, large subun...   235   1e-59
ref|ZP_01708877.1|  hypothetical protein Faci_03000940 [Ferr...   235   1e-59
ref|YP_001875296.1|  homoaconitate hydratase family protein ...   235   1e-59
ref|ZP_03929473.1|  possible aconitate hydratase [Anaerococc...   235   1e-59
ref|YP_878649.1|  aconitate hydratase [Clostridium novyi NT]...   234   2e-59
ref|ZP_03856032.1|  3-isopropylmalate dehydratase, large sub...   234   2e-59
ref|YP_001884557.1|  3-isopropylmalate dehydratase, large su...   234   2e-59
ref|ZP_02078787.1|  hypothetical protein CLOLEP_00224 [Clost...   234   2e-59
ref|NP_634397.1|  3-isopropylmalate dehydratase [Methanosarc...   234   3e-59
ref|YP_001180124.1|  3-isopropylmalate dehydratase large sub...   233   3e-59
ref|NP_906793.1|  3-ISOPROPYLMALATE DEHYDRATASE, LARGE SUBUN...   233   3e-59
ref|ZP_03893713.1|  3-isopropylmalate dehydratase, large sub...   233   4e-59
sp|Q8PUG1|LEU22_METMA  3-isopropylmalate dehydratase large s...   233   5e-59
ref|YP_001919738.1|  3-isopropylmalate dehydratase, large su...   233   5e-59
ref|ZP_02621054.1|  putative aconitate hydratase [Clostridiu...   233   6e-59
ref|ZP_02742090.1|  aconitate hydratase [Clostridium diffici...   232   1e-58
ref|ZP_03916351.1|  possible aconitate hydratase [Anaerococc...   231   1e-58
ref|YP_001665791.1|  putative aconitate hydratase [Thermoana...   231   1e-58
ref|YP_001273296.1|  3-isopropylmalate dehydratase, LeuC [Me...   231   2e-58
ref|ZP_02726948.1|  aconitate hydratase [Clostridium diffici...   231   2e-58
ref|YP_431084.1|  3-isopropylmalate dehydratase large subuni...   231   2e-58
ref|YP_001087310.1|  aconitate hydratase [Clostridium diffic...   230   2e-58
ref|YP_001435518.1|  3-isopropylmalate dehydratase, large su...   230   4e-58
ref|YP_001096966.1|  homoaconitate hydratase family protein ...   229   5e-58
ref|NP_614723.1|  3-isopropylmalate dehydratase large subuni...   229   5e-58
ref|NP_622150.1|  aconitate hydratase [Thermoanaerobacter te...   229   7e-58
ref|YP_001568607.1|  3-isopropylmalate dehydratase, large su...   229   7e-58
ref|NP_860667.1|  3-isopropylmalate dehydratase large subuni...   229   8e-58
gb|EAY57416.1|  Aconitase A [Leptospirillum sp. Group II UBA]     229   8e-58
ref|YP_001716546.1|  3-isopropylmalate dehydratase, large su...   229   8e-58
ref|YP_685653.1|  3-isopropylmalate dehydratase, large subun...   229   8e-58
ref|YP_001087471.1|  3-isopropylmalate dehydratase large sub...   228   9e-58
ref|YP_753086.1|  3-isopropylmalate dehydratase [Syntrophomo...   228   1e-57
ref|ZP_02729514.1|  3-isopropylmalate dehydratase large subu...   228   1e-57
ref|NP_228364.1|  3-isopropylmalate dehydratase, large subun...   228   1e-57
ref|NP_621730.1|  3-isopropylmalate dehydratase large subuni...   228   2e-57
ref|YP_001243970.1|  3-isopropylmalate dehydratase, large su...   227   2e-57
ref|YP_001211082.1|  3-isopropylmalate dehydratase large sub...   227   2e-57
ref|YP_394526.1|  Cis-homoaconitase:3-isopropylmalate dehydr...   227   2e-57
ref|ZP_02862666.1|  hypothetical protein ANASTE_01887 [Anaer...   227   3e-57
ref|YP_001273873.1|  3-isopropylmalate dehydratase, large su...   227   3e-57
ref|YP_001322990.1|  homoaconitate hydratase family protein ...   227   3e-57
ref|YP_001320772.1|  3-isopropylmalate dehydratase [Alkaliph...   227   3e-57
ref|YP_001678741.1|  aconitate hydratase, putative [Heliobac...   227   3e-57
ref|ZP_02862126.1|  hypothetical protein ANASTE_01339 [Anaer...   226   3e-57
ref|NP_988269.1|  3-isopropylmalate dehydratase [Methanococc...   226   3e-57
ref|NP_349770.1|  3-isopropylmalate dehydratase large subuni...   226   4e-57
ref|YP_462618.1|  3-isopropylmalate dehydratase large subuni...   226   4e-57
gb|EEH99428.1|  aconitate hydratase [Clostridium sp. 7_2_43FAA]   226   4e-57
ref|YP_181192.1|  3-isopropylmalate dehydratase large subuni...   226   7e-57
ref|YP_001321244.1|  3-isopropylmalate dehydratase, large su...   226   7e-57
ref|ZP_02027506.1|  hypothetical protein EUBVEN_02781 [Eubac...   226   7e-57
ref|YP_001319181.1|  aconitate hydratase [Alkaliphilus metal...   225   8e-57
ref|YP_001329619.1|  homoaconitate hydratase family protein ...   225   8e-57
ref|YP_001038606.1|  3-isopropylmalate dehydratase large sub...   225   9e-57
ref|ZP_02208183.1|  hypothetical protein COPEUT_03010 [Copro...   225   9e-57
ref|YP_001214209.1|  3-isopropylmalate dehydratase, large su...   225   1e-56
ref|ZP_02076019.1|  hypothetical protein CLOL250_02807 [Clos...   225   1e-56
ref|YP_001560448.1|  3-isopropylmalate dehydratase, large su...   225   1e-56
ref|YP_001661675.1|  3-isopropylmalate dehydratase, large su...   224   1e-56
ref|ZP_02693160.1|  3-isopropylmalate dehydratase, large sub...   224   2e-56
ref|ZP_02087786.1|  hypothetical protein CLOBOL_05331 [Clost...   224   2e-56
ref|YP_001275412.1|  3-isopropylmalate dehydratase [Roseifle...   224   2e-56
ref|ZP_02204331.1|  homoaconitate hydratase family protein [...   224   3e-56
ref|YP_307871.1|  3-isopropylmalate dehydratase, large subun...   224   3e-56
ref|ZP_02868666.1|  hypothetical protein CLOSPI_02509 [Clost...   223   3e-56
emb|CAJ73630.1|  similar to aconitase 1 (aconitate hydratase...   223   3e-56
ref|YP_448126.1|  LeuC2 [Methanosphaera stadtmanae DSM 3091]...   223   4e-56
ref|ZP_01962793.1|  hypothetical protein RUMOBE_00506 [Rumin...   223   4e-56
ref|ZP_02429751.1|  hypothetical protein CLORAM_03174 [Clost...   223   5e-56
gb|EEH96489.1|  3-isopropylmalate dehydratase large subunit ...   223   6e-56
ref|ZP_02950641.1|  3-isopropylmalate dehydratase, large sub...   222   7e-56
ref|YP_001433542.1|  homoaconitate hydratase family protein ...   222   7e-56
ref|ZP_02442778.1|  hypothetical protein ANACOL_02071 [Anaer...   222   8e-56
ref|ZP_02133049.1|  putative aconitate hydratase [Desulfatib...   222   1e-55
ref|ZP_02090234.1|  hypothetical protein FAEPRAM212_00473 [F...   221   1e-55
ref|YP_001307360.1|  3-isopropylmalate dehydratase, large su...   221   1e-55
ref|YP_687015.1|  3-isopropylmalate dehydratase, large subun...   221   1e-55
ref|YP_001549565.1|  homoaconitate hydratase family protein ...   221   1e-55
ref|ZP_02437961.1|  hypothetical protein CLOSS21_00399 [Clos...   221   2e-55
ref|NP_247997.1|  3-isopropylmalate dehydratase (leuC) [Meth...   221   2e-55
ref|ZP_00110701.1|  COG0065: 3-isopropylmalate dehydratase l...   221   2e-55
ref|ZP_02081473.1|  hypothetical protein CLOLEP_02949 [Clost...   221   2e-55
ref|ZP_01574590.1|  3-isopropylmalate dehydratase, large sub...   221   2e-55
ref|YP_001179560.1|  aconitate hydratase [Caldicellulosirupt...   221   2e-55
ref|ZP_02211525.1|  hypothetical protein CLOBAR_01138 [Clost...   221   2e-55
ref|YP_843217.1|  3-isopropylmalate dehydratase [Methanosaet...   221   2e-55
ref|YP_001664025.1|  3-isopropylmalate dehydratase, large su...   220   3e-55
ref|YP_001357464.1|  3-isopropylmalate dehydratase, large su...   220   3e-55
ref|YP_430725.1|  aconitate hydratase [Moorella thermoacetic...   220   4e-55
dbj|BAG13938.1|  3-isopropylmalate dehydratase large subunit...   219   5e-55
ref|YP_001213888.1|  3-isopropylmalate dehydratase large sub...   219   7e-55
ref|YP_001680099.1|  3-isopropylmalate dehydratase, large su...   218   1e-54
ref|ZP_02420896.1|  hypothetical protein ANACAC_03543 [Anaer...   218   1e-54
ref|ZP_01872015.1|  3-ISOPROPYLMALATE DEHYDRATASE, LARGE SUB...   218   1e-54
ref|YP_307529.1|  3-isopropylmalate dehydratase large subuni...   218   1e-54
ref|YP_001405232.1|  3-isopropylmalate dehydratase [Candidat...   218   1e-54
ref|YP_001357132.1|  3-isopropylmalate dehydratase, large su...   218   1e-54
ref|YP_517602.1|  hypothetical protein DSY1369 [Desulfitobac...   218   2e-54
sp|Q24XT4|LEU2_DESHY  3-isopropylmalate dehydratase large su...   218   2e-54
ref|ZP_01188446.1|  Cis-homoaconitase:3-isopropylmalate dehy...   217   2e-54
ref|NP_214222.1|  aconitate hydratase [Aquifex aeolicus VF5]...   217   3e-54
ref|YP_001096630.1|  homoaconitate hydratase family protein ...   216   4e-54
ref|NP_247475.1|  3-isopropylmalate dehydratase (leuC) [Meth...   216   4e-54
ref|ZP_01968310.1|  hypothetical protein RUMTOR_01878 [Rumin...   216   5e-54
ref|YP_001329942.1|  homoaconitate hydratase family protein ...   216   6e-54
ref|ZP_01666731.1|  homoaconitate hydratase family protein [...   216   6e-54
ref|YP_644465.1|  homoaconitate hydratase family protein [Ru...   216   6e-54
ref|ZP_02042561.1|  hypothetical protein RUMGNA_03363 [Rumin...   216   6e-54
ref|YP_001467598.1|  3-isopropylmalate dehydratase, large su...   216   7e-54
ref|ZP_02036397.1|  hypothetical protein BACCAP_01999 [Bacte...   215   8e-54
ref|YP_566874.1|  3-isopropylmalate dehydratase [Methanococc...   215   1e-53
ref|YP_687329.1|  3-isopropylmalate dehydratase, large subun...   214   1e-53
ref|NP_070787.1|  aconitase (acn) [Archaeoglobus fulgidus DS...   214   2e-53
sp|O28316|LEU21_ARCFU  3-isopropylmalate dehydratase large s...   214   2e-53
ref|YP_359380.1|  3-isopropylmalate dehydratase large subuni...   214   2e-53
ref|YP_001549239.1|  homoaconitate hydratase family protein ...   214   2e-53
ref|ZP_01962795.1|  hypothetical protein RUMOBE_00508 [Rumin...   214   3e-53
ref|YP_001047857.1|  homoaconitate hydratase family protein ...   213   3e-53
ref|ZP_01666723.1|  3-isopropylmalate dehydratase [Thermosin...   213   3e-53
ref|YP_387900.1|  aconitate hydratase [Desulfovibrio desulfu...   213   3e-53
ref|ZP_02433282.1|  hypothetical protein CLOSCI_03560 [Clost...   213   3e-53
ref|ZP_02193658.1|  3-isopropylmalate dehydratase [Methanoco...   213   4e-53
ref|ZP_01629947.1|  3-isopropylmalate dehydratase, LeuC subu...   213   4e-53
ref|YP_566516.1|  3-isopropylmalate dehydratase [Methanococc...   213   6e-53
ref|YP_001489033.1|  3-isopropylmalate dehydratase, large su...   213   7e-53
ref|ZP_01995089.1|  hypothetical protein DORLON_01080 [Dorea...   212   7e-53
ref|ZP_02437959.1|  hypothetical protein CLOSS21_00397 [Clos...   212   8e-53
ref|ZP_02132333.1|  3-isopropylmalate dehydratase, large sub...   212   1e-52
ref|YP_001324490.1|  homoaconitate hydratase family protein ...   211   1e-52
ref|YP_001324511.1|  3-isopropylmalate dehydratase [Methanoc...   211   1e-52
ref|ZP_02235471.1|  hypothetical protein DORFOR_02357 [Dorea...   211   1e-52
ref|YP_754804.1|  3-isopropylmalate dehydratase large subuni...   210   3e-52
ref|YP_001409010.1|  3-isopropylmalate dehydratase, large su...   210   4e-52
ref|YP_001323307.1|  homoaconitate hydratase family protein ...   210   4e-52
ref|ZP_03871645.1|  aconitase [Halorhabdus utahensis DSM 129...   209   6e-52
ref|YP_886844.1|  3-isopropylmalate dehydratase large subuni...   209   7e-52
ref|ZP_02177697.1|  aconitate hydratase [Hydrogenivirga sp. ...   209   8e-52
ref|ZP_03929231.1|  3-isopropylmalate dehydratase large subu...   209   9e-52
ref|YP_299576.1|  Cis-homoaconitase [Ralstonia eutropha JMP1...   209   9e-52
ref|NP_276502.1|  3-isopropylmalate dehydratase, LeuD subuni...   208   1e-51
ref|NP_988600.1|  aconitase Family [Methanococcus maripaludi...   208   1e-51
ref|ZP_02078010.1|  hypothetical protein EUBDOL_01817 [Eubac...   208   1e-51
ref|YP_891058.1|  3-isopropylmalate dehydratase large subuni...   208   1e-51
ref|ZP_02016778.1|  3-isopropylmalate dehydratase [Halorubru...   208   1e-51
ref|YP_001111660.1|  3-isopropylmalate dehydratase large sub...   208   1e-51
ref|YP_891400.1|  3-isopropylmalate dehydratase, large subun...   208   1e-51
ref|YP_001405737.1|  3-isopropylmalate dehydratase, large su...   207   2e-51
ref|NP_885808.1|  putative 3-isopropylmalate dehydratase lar...   207   3e-51
ref|YP_305477.1|  3-isopropylmalate dehydratase, large subun...   207   3e-51
ref|NP_632433.1|  3-isopropylmalate dehydratase [Methanosarc...   207   3e-51
ref|YP_842722.1|  aconitate hydratase [Methanosaeta thermoph...   206   5e-51
ref|NP_617978.1|  3-isopropylmalate dehydratase, large subun...   206   7e-51
ref|ZP_02086113.1|  hypothetical protein CLOBOL_03656 [Clost...   206   7e-51
ref|YP_001737401.1|  3-isopropylmalate dehydratase [Candidat...   206   8e-51
ref|YP_587996.1|  homoaconitate hydratase family protein [Ra...   205   1e-50
ref|YP_254963.1|  3-isopropylmalate dehydratase large subuni...   204   2e-50
ref|YP_001736635.1|  homoaconitate hydratase family protein ...   203   4e-50
ref|NP_952952.1|  3-isopropylmalate dehydratase, large subun...   202   7e-50
ref|ZP_01594511.1|  homoaconitate hydratase family protein [...   202   8e-50
ref|ZP_01575551.1|  homoaconitate hydratase family protein [...   202   1e-49
ref|ZP_00590388.1|  Cis-homoaconitase [Pelodictyon phaeoclat...   201   2e-49
ref|NP_281140.1|  aconitate hydratase [Halobacterium sp. NRC...   201   2e-49
ref|YP_136708.1|  aconitate hydratase [Haloarcula marismortu...   200   3e-49
ref|YP_001796494.1|  3-isopropylmalate dehydratase large sub...   200   4e-49
dbj|BAD81058.1|  aconitase [Acidithiobacillus thiooxidans]        200   4e-49
ref|YP_503784.1|  homoaconitate hydratase family protein [Me...   199   5e-49
ref|XP_001821962.1|  hypothetical protein [Aspergillus oryza...   199   7e-49
ref|NP_961189.1|  hypothetical protein MAP2255 [Mycobacteriu...   199   8e-49
ref|YP_001546066.1|  3-isopropylmalate dehydratase [Herpetos...   199   9e-49
ref|ZP_01467328.1|  aconitate hydratase [Stigmatella auranti...   198   1e-48
ref|YP_880967.1|  3-isopropylmalate dehydratase large subuni...   198   1e-48
ref|YP_384229.1|  Cis-homoaconitase:3-isopropylmalate dehydr...   198   1e-48
ref|YP_374527.1|  3-isopropylmalate dehydratase [Pelodictyon...   198   1e-48
ref|YP_001403760.1|  3-isopropylmalate dehydratase [Candidat...   198   2e-48
ref|YP_847096.1|  3-isopropylmalate dehydratase, large subun...   198   2e-48
ref|YP_001030048.1|  hypothetical protein Mlab_0607 [Methano...   197   2e-48
ref|YP_001581754.1|  3-isopropylmalate dehydratase [Nitrosop...   197   2e-48
ref|YP_325864.1|  aconitate hydratase [Natronomonas pharaoni...   197   3e-48
ref|XP_001241042.1|  hypothetical protein CIMG_08205 [Coccid...   197   3e-48
ref|ZP_03872275.1|  aconitase [Halomicrobium mukohataei DSM ...   197   3e-48
ref|ZP_01667793.1|  homoaconitate hydratase family protein [...   197   3e-48
ref|YP_001232435.1|  homoaconitate hydratase family protein ...   197   3e-48
ref|XP_001399461.1|  hypothetical protein An02g03250 [Asperg...   196   6e-48
ref|ZP_01389737.1|  homoaconitate hydratase family protein:3...   196   7e-48
ref|ZP_01774685.1|  homoaconitate hydratase family protein [...   195   1e-47
ref|YP_604498.1|  homoaconitate hydratase family protein [De...   195   1e-47
ref|YP_001630273.1|  leuC1 [Bordetella petrii DSM 12804] >gi...   194   2e-47
ref|YP_001190929.1|  3-isopropylmalate dehydratase large sub...   194   2e-47
ref|YP_002785913.1|  putative 3-isopropylmalate dehydratase,...   194   2e-47
ref|ZP_03999029.1|  aconitase [Halogeometricum borinquense D...   194   2e-47
ref|ZP_01804711.1|  hypothetical protein CdifQ_04000915 [Clo...   194   3e-47
ref|YP_001540984.1|  3-isopropylmalate dehydratase [Caldivir...   194   3e-47
ref|YP_299035.1|  Cis-homoaconitase [Ralstonia eutropha JMP1...   193   3e-47
ref|XP_566619.1|  3-isopropylmalate dehydratase [Cryptococcu...   193   5e-47
ref|YP_445601.1|  aconitate hydratase [Salinibacter ruber DS...   192   7e-47
ref|YP_876410.1|  3-isopropylmalate dehydratase large subuni...   191   1e-46
>ref|NP_010520.1| Homoaconitase, catalyzes the conversion of homocitrate to
           homoisocitrate, which is a step in the lysine
           biosynthesis pathway; Lys4p [Saccharomyces cerevisiae]
 sp|P49367|LYS4_YEAST Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAA63764.1| homoaconitase [Saccharomyces cerevisiae]
 gb|AAA88902.1| lysine biosynthesis enzyme homoaconitase [Saccharomyces cerevisiae]
          Length = 693

 Score = 1389 bits (3595), Expect = 0.0,   Method: Composition-based stats.
 Identities = 693/693 (100%), Positives = 693/693 (100%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG
Sbjct: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW
Sbjct: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI
Sbjct: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD
Sbjct: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP
Sbjct: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE
Sbjct: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
           IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV
Sbjct: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
           PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG
Sbjct: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD
Sbjct: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL
Sbjct: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
>gb|AAU09698.1| YDR234W [Saccharomyces cerevisiae]
          Length = 693

 Score = 1388 bits (3592), Expect = 0.0,   Method: Composition-based stats.
 Identities = 692/693 (99%), Positives = 693/693 (100%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG
Sbjct: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW
Sbjct: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI
Sbjct: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD
Sbjct: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP
Sbjct: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE
Sbjct: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
           IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV
Sbjct: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
           PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSRE+AATALLAKGINLVVSGSFG
Sbjct: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSRERAATALLAKGINLVVSGSFG 600

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD
Sbjct: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL
Sbjct: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
>gb|EDN60567.1| homoaconitase [Saccharomyces cerevisiae YJM789]
          Length = 693

 Score = 1377 bits (3565), Expect = 0.0,   Method: Composition-based stats.
 Identities = 688/693 (99%), Positives = 688/693 (99%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLRSTT TRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRSTTLTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGATKIKNPSQIV TLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG
Sbjct: 61  WPVALKFMGLGATKIKNPSQIVNTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLNM VASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 121 IGHQIMIEEGYAFPLNMAVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW
Sbjct: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKI KADKDAHYAKKLI
Sbjct: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKILKADKDAHYAKKLI 300

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD
Sbjct: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP
Sbjct: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKI SPAEVLSTSEIPFSGVKTE
Sbjct: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKIGSPAEVLSTSEIPFSGVKTE 480

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
           IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV
Sbjct: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
           PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG
Sbjct: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD
Sbjct: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL
Sbjct: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
>ref|XP_452878.1| unnamed protein product [Kluyveromyces lactis]
 sp|Q6CT61|LYS4_KLULA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAH01729.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
          Length = 693

 Score = 1130 bits (2923), Expect = 0.0,   Method: Composition-based stats.
 Identities = 548/687 (79%), Positives = 610/687 (88%), Gaps = 3/687 (0%)

Query: 9   RSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFM 68
           R F +SRA   GQN+TEKIVQ +AV LPEGK V SGDYVSIKPAHCMSHDNSWPVALKFM
Sbjct: 8   RMFSTSRALYAGQNMTEKIVQRHAVGLPEGKTVVSGDYVSIKPAHCMSHDNSWPVALKFM 67

Query: 69  GLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIE 128
           GLGA+ IKNP Q+V TLDHD+QNKSEKNLTKYKNIENFAKKH ID YPAGRGIGHQIMIE
Sbjct: 68  GLGASTIKNPRQVVNTLDHDVQNKSEKNLTKYKNIENFAKKHGIDFYPAGRGIGHQIMIE 127

Query: 129 EGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQL 188
           EGYAFPL MTVASDSHSNTYGG+G+LGTPIVRTDAAAIWATGQTWWQIPPVAQVELKG+L
Sbjct: 128 EGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGEL 187

Query: 189 PQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFP 248
           P G+SGKDIIVALCG+FN DQVLNHAIEFTGDSL+ +PID+RLTIANMTTEWGALSGLFP
Sbjct: 188 PAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEWGALSGLFP 247

Query: 249 VDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           VD  L+D+Y+NRL K+G NNHPRIN   I  L+ K+   +AD DA YAKKLIIDL+TLTH
Sbjct: 248 VDNVLLDFYRNRLTKVG-NNHPRINEARINELQAKSDSLQADPDAKYAKKLIIDLSTLTH 306

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVA 368
           YVSGPNSVK+S+TV DLS+QDIK+NKAYLVSCTNSRLSDL+SAA+VVCP+GD+N+V+KVA
Sbjct: 307 YVSGPNSVKISSTVDDLSKQDIKVNKAYLVSCTNSRLSDLESAANVVCPSGDINQVHKVA 366

Query: 369 PGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISAT 428
            GVEFY+AAASSE+EA+AR +GAW+KLL AGC+PLP+GCGPCIGLG GLLE G+VGISAT
Sbjct: 367 EGVEFYIAAASSEVEAEARATGAWQKLLNAGCLPLPAGCGPCIGLGTGLLEEGQVGISAT 426

Query: 429 NRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVE 488
           NRNFKGRMGSKDALAYLASP+VVAASA+LGKI SPAEVL T +  F+GV   + + P   
Sbjct: 427 NRNFKGRMGSKDALAYLASPSVVAASAILGKIGSPAEVLGTKDPNFTGVVATVEDAPATS 486

Query: 489 EEVN--AQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMA 546
            +    A       SVEILEGFP E SGELVLCDADNINTDGIYPGKYTYQDDVPKE MA
Sbjct: 487 ADGKDVADESGASGSVEILEGFPSEISGELVLCDADNINTDGIYPGKYTYQDDVPKETMA 546

Query: 547 QVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRN 606
           +VCMENYD +F+TK +PGDI++SGFNFGTGSSREQAATA+LAKGI LVVSGSFGNIF RN
Sbjct: 547 KVCMENYDPDFQTKANPGDILISGFNFGTGSSREQAATAILAKGIKLVVSGSFGNIFFRN 606

Query: 607 SINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILE 666
           SINNALLTLEIPALI  LR++Y+ APKELTRRTGWFLKWDV+ AKV VTEGS++GP++LE
Sbjct: 607 SINNALLTLEIPALINMLRDRYKDAPKELTRRTGWFLKWDVSQAKVYVTEGSVNGPIVLE 666

Query: 667 QKVGELGKNLQEIIVKGGLEGWVKSQL 693
           QKVGELGKNLQEIIVKGGLE WVKSQL
Sbjct: 667 QKVGELGKNLQEIIVKGGLESWVKSQL 693
>ref|XP_448693.1| unnamed protein product [Candida glabrata]
 sp|Q6FM51|LYS4_CANGA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAG61656.1| unnamed protein product [Candida glabrata CBS 138]
          Length = 689

 Score = 1077 bits (2785), Expect = 0.0,   Method: Composition-based stats.
 Identities = 537/685 (78%), Positives = 592/685 (86%), Gaps = 1/685 (0%)

Query: 9   RSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFM 68
           RSFH      +GQNLTEKIVQ Y+V L  GK VHSGDYVSIKPAH MSHDNSWPVALKFM
Sbjct: 6   RSFHVYTRLQRGQNLTEKIVQQYSVGLAPGKRVHSGDYVSIKPAHVMSHDNSWPVALKFM 65

Query: 69  GLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIE 128
            LGA  +K+P QIV TLDHDIQNKS+KNLTKY+NIE+FAKKH ID YPAGRGIGHQIM+E
Sbjct: 66  NLGARTVKDPRQIVNTLDHDIQNKSDKNLTKYRNIESFAKKHGIDFYPAGRGIGHQIMVE 125

Query: 129 EGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQL 188
           EGYAFPLN+TVASDSHSNTYGG+G+LGTP+VRTDAAAIWATGQTWWQIPPVAQVE KG+L
Sbjct: 126 EGYAFPLNLTVASDSHSNTYGGMGALGTPVVRTDAAAIWATGQTWWQIPPVAQVEFKGKL 185

Query: 189 PQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFP 248
            + VSGKDIIVALCG+FN DQVLNHAIEFTGD++  LP+D RLTIANMTTEWGALSGLFP
Sbjct: 186 HESVSGKDIIVALCGVFNKDQVLNHAIEFTGDAIKHLPVDFRLTIANMTTEWGALSGLFP 245

Query: 249 VDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           VD TLI+WYKNRL  +G N HPRIN  TI+ LE+KAK+ KAD DA YAKKL+IDL+TLTH
Sbjct: 246 VDDTLINWYKNRLNIVGPN-HPRINETTIKNLEDKAKVFKADSDAVYAKKLVIDLSTLTH 304

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVA 368
           YVSGPNSVKVSNTVQDL++ +IKINKAYLVSCTN+RLSDL+SAA VVCPTGDL+KVNKVA
Sbjct: 305 YVSGPNSVKVSNTVQDLARDNIKINKAYLVSCTNARLSDLESAAKVVCPTGDLSKVNKVA 364

Query: 369 PGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISAT 428
            GVEFY AAASSEIE +A + G W+ LL AGC PLPSGCGPCIGLGAGLLEPGEVGISAT
Sbjct: 365 DGVEFYFAAASSEIEKEAAEKGIWQALLAAGCKPLPSGCGPCIGLGAGLLEPGEVGISAT 424

Query: 429 NRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVE 488
           NRNFKGRMGSKDALAYLASPAVVAASAVLG+I SPAEV    ++  SG+  E +      
Sbjct: 425 NRNFKGRMGSKDALAYLASPAVVAASAVLGRIGSPAEVWGIEDVKSSGLLAEELACNTET 484

Query: 489 EEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQV 548
                 +E     VE+LEGFP E  GELVLCDADN+NTDGIYPGKYTYQDDV +E MAQV
Sbjct: 485 STATPVSEGSAAKVEMLEGFPEEIVGELVLCDADNVNTDGIYPGKYTYQDDVSRETMAQV 544

Query: 549 CMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSI 608
           CMENYD EF +K + GDI+VSGFNFGTGSSREQAAT+LLAKGINLVV+GSF N FSRNSI
Sbjct: 545 CMENYDGEFGSKANAGDILVSGFNFGTGSSREQAATSLLAKGINLVVAGSFSNTFSRNSI 604

Query: 609 NNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQK 668
           NNALLTLEIP L++KLR K++ APKELTRRTGWFLKWDV +AKV VTEGS DG V+LEQK
Sbjct: 605 NNALLTLEIPTLVEKLRSKFENAPKELTRRTGWFLKWDVPNAKVYVTEGSPDGQVLLEQK 664

Query: 669 VGELGKNLQEIIVKGGLEGWVKSQL 693
           VGELGKNLQEII+KGGLEGWVKSQL
Sbjct: 665 VGELGKNLQEIIIKGGLEGWVKSQL 689
>ref|XP_001646008.1| hypothetical protein Kpol_1031p57 [Vanderwaltozyma polyspora DSM
           70294]
 gb|EDO18150.1| hypothetical protein Kpol_1031p57 [Vanderwaltozyma polyspora DSM
           70294]
          Length = 689

 Score = 1041 bits (2692), Expect = 0.0,   Method: Composition-based stats.
 Identities = 521/696 (74%), Positives = 586/696 (84%), Gaps = 11/696 (1%)

Query: 1   MLRSTTFTRSFHSSRAWL-KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDN 59
           MLR   F R F      L +GQNLTEKIVQ YAV LPEGK V SGDYVSI+P++CMSHDN
Sbjct: 1   MLR---FKRFFSEGSIRLTRGQNLTEKIVQRYAVELPEGKKVFSGDYVSIRPSYCMSHDN 57

Query: 60  SWPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGR 119
           SWP+ALKFMGLGATK+K P QIV TLDHD+QNKSEKNLTKY+NIENFAKKH    YPAGR
Sbjct: 58  SWPIALKFMGLGATKLKYPDQIVNTLDHDVQNKSEKNLTKYRNIENFAKKHGSHFYPAGR 117

Query: 120 GIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPV 179
           GIGHQIMIEEGYAFPLN+TVASDSHSN YGG+G LGTPIVRTDAA+IWATGQTWWQIPPV
Sbjct: 118 GIGHQIMIEEGYAFPLNLTVASDSHSNIYGGVGCLGTPIVRTDAASIWATGQTWWQIPPV 177

Query: 180 AQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTE 239
           AQVELKG+LP GVSGKDIIVALCGLFN+DQVLNHAIEFTGDS+  L ID+RLTIANMTTE
Sbjct: 178 AQVELKGELPTGVSGKDIIVALCGLFNDDQVLNHAIEFTGDSIKNLSIDNRLTIANMTTE 237

Query: 240 WGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKL 299
           WGALSGLFPVD T+I WYK R+ K+G  +   IN K I  LE+ A+  KAD ++ Y KKL
Sbjct: 238 WGALSGLFPVDSTVIQWYKERINKVGEGH--IINSKAIEELEQNAQKLKADSNSKYDKKL 295

Query: 300 IIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTG 359
            IDL+TLT+YVSGPNSVK+SN V+DLS+QDIKINKAYLVSCTNSRLSD+++AADVVCPTG
Sbjct: 296 TIDLSTLTYYVSGPNSVKISNPVEDLSKQDIKINKAYLVSCTNSRLSDIEAAADVVCPTG 355

Query: 360 DLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLE 419
           ++  V KVAPGV FY+AAASSE+E +AR SGAW+KLLKAGCI LP+GCGPCIGLG GLLE
Sbjct: 356 NIEDVKKVAPGVNFYIAAASSEVEKEARTSGAWDKLLKAGCIALPAGCGPCIGLGTGLLE 415

Query: 420 PGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKT 479
            GEVGISATNRNFKGRMGSKDALAYLASPAVVAASA+ GKI SP E L      ++ VKT
Sbjct: 416 AGEVGISATNRNFKGRMGSKDALAYLASPAVVAASALAGKIVSPNEALGIESCKYASVKT 475

Query: 480 EIIENPVVEEEVNAQTEAPKQS--VEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQ 537
                 ++EEE +  +  P ++  VEILEGFP E SGELV CDADNINTDGIYPGKYTYQ
Sbjct: 476 ---SEQILEEETSGTSSGPTEASRVEILEGFPSEISGELVFCDADNINTDGIYPGKYTYQ 532

Query: 538 DDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSG 597
           DD+ KE MA+VCMENYD EF+TK   GDI++SGFNFGTGSSREQAAT +LA+GINLVVSG
Sbjct: 533 DDISKEMMAEVCMENYDPEFQTKTKTGDIIISGFNFGTGSSREQAATCILARGINLVVSG 592

Query: 598 SFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEG 657
           SFGNIFSRNSINN LLT+E+P LI++LR KY+    ELTRRTGWF KWDVA+  V V EG
Sbjct: 593 SFGNIFSRNSINNGLLTVEVPKLIEQLRSKYKDDTPELTRRTGWFFKWDVANKNVTVREG 652

Query: 658 SLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           SL G ++ EQ++ ELGKNLQEIIVKGGLEGWVKS+L
Sbjct: 653 SLTGTIVFEQEIPELGKNLQEIIVKGGLEGWVKSKL 688
>ref|XP_001383888.2| homoaconitase [Pichia stipitis CBS 6054]
 gb|ABN65859.2| homoaconitase [Pichia stipitis CBS 6054]
          Length = 677

 Score =  983 bits (2540), Expect = 0.0,   Method: Composition-based stats.
 Identities = 495/691 (71%), Positives = 570/691 (82%), Gaps = 30/691 (4%)

Query: 9   RSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFM 68
           R   +S   L+GQNLTEKIVQ YAVNLP GK V SGDYVSIKPAHCMSHDNSWPVA KFM
Sbjct: 7   RGLATSARLLRGQNLTEKIVQRYAVNLPAGKQVFSGDYVSIKPAHCMSHDNSWPVATKFM 66

Query: 69  GLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIE 128
           GLGATK+K+  QIV TLDHD+QNKSEKNL KY+NIE FAK+  ID YPAGRGIGHQIMIE
Sbjct: 67  GLGATKVKDNRQIVCTLDHDVQNKSEKNLEKYRNIEQFAKEQGIDFYPAGRGIGHQIMIE 126

Query: 129 EGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQL 188
           EGYAFPLN+TVASDSHSNTYGG+GSLGTPIVRTDAA+IWATGQTWWQIPPVA+VEL+G+L
Sbjct: 127 EGYAFPLNLTVASDSHSNTYGGVGSLGTPIVRTDAASIWATGQTWWQIPPVAKVELQGKL 186

Query: 189 PQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFP 248
           P GV+GKDIIVALCG FN D+VLNHAIEF GD +  L ID+RLTIANMTTEWGALSGLFP
Sbjct: 187 PAGVTGKDIIVALCGAFNKDEVLNHAIEFVGDGIEHLSIDYRLTIANMTTEWGALSGLFP 246

Query: 249 VDKTLIDWYKN-RLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLT 307
           VD  L+DWY++ RL KLG+  HPR+N KT+ ALE+     ++D DA YAK L++DL++LT
Sbjct: 247 VDARLLDWYRSERLAKLGS-GHPRVNDKTVSALEKNPV--QSDSDAVYAKHLVVDLSSLT 303

Query: 308 HYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKV 367
            Y+SGPNSVK+SN++ DL +QDI INKAYLVSCTNSRLSD+Q+AADV+       + +KV
Sbjct: 304 PYISGPNSVKISNSLADLVEQDIPINKAYLVSCTNSRLSDIQAAADVI-------RGHKV 356

Query: 368 APGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISA 427
           APGVEFYVAAASS ++ DA  +GAW+ +L+AG  PLP+GCGPCIGLG GLL+ GEVGISA
Sbjct: 357 APGVEFYVAAASSNVQKDAEAAGAWKTILEAGAKPLPAGCGPCIGLGTGLLKDGEVGISA 416

Query: 428 TNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAE-----VLSTSEIPFSGVKTEII 482
           TNRNFKGRMGSKDALAYLASP VVAASAVLG+I  P E     VLST EI    +KT   
Sbjct: 417 TNRNFKGRMGSKDALAYLASPEVVAASAVLGRIGGPQELEGKSVLSTREI----IKT--- 469

Query: 483 ENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPK 542
               +EE   ++  A   +VE+LEGFP+   GEL+LCDADNINTDGIYPGKYTYQDD+P+
Sbjct: 470 ----IEETKVSEDAATGGAVEVLEGFPKVIEGELILCDADNINTDGIYPGKYTYQDDIPR 525

Query: 543 EKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNI 602
           EKMA+VCMENYDAEF  K   GDI++SG+NFGTGSSREQAATA+LA+G+ LVV+GSFGNI
Sbjct: 526 EKMAEVCMENYDAEFNGKTKAGDIIISGYNFGTGSSREQAATAILARGMKLVVAGSFGNI 585

Query: 603 FSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGP 662
           FSRNSINNALLTLEIP LI  LR KY G+  ELT RTGW LKWDV  A V V +   +G 
Sbjct: 586 FSRNSINNALLTLEIPDLINNLRAKYAGS-DELTVRTGWILKWDVTTATVEVKDS--EGN 642

Query: 663 VILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           V+L+QKVGELG NLQ+IIVKGGLEGWV+S+L
Sbjct: 643 VVLKQKVGELGTNLQDIIVKGGLEGWVRSEL 673
>ref|XP_001485749.1| hypothetical protein PGUG_01420 [Pichia guilliermondii ATCC 6260]
 gb|EDK37322.1| hypothetical protein PGUG_01420 [Pichia guilliermondii ATCC 6260]
          Length = 674

 Score =  968 bits (2502), Expect = 0.0,   Method: Composition-based stats.
 Identities = 478/685 (69%), Positives = 562/685 (82%), Gaps = 16/685 (2%)

Query: 9   RSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFM 68
           R F +    L+GQNLTEKIVQ YAV +  GK V SGDYV+IKPAHCMSHDNSWPVA KFM
Sbjct: 5   RQFSTGLRALRGQNLTEKIVQKYAVGVAPGKKVVSGDYVTIKPAHCMSHDNSWPVATKFM 64

Query: 69  GLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIE 128
           GLGATK+K+  Q+V TLDHD+QN+SE N+ KY NIE FA +  ID YPAGRGIGHQIMIE
Sbjct: 65  GLGATKVKDNRQVVCTLDHDVQNRSESNMKKYANIEKFATEQGIDFYPAGRGIGHQIMIE 124

Query: 129 EGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQL 188
           EGYAFP N+TVASD HSNTYGG+GSLGTPIVRTDAAAIWATGQTWWQIPPVA+VE  G+L
Sbjct: 125 EGYAFPHNLTVASDLHSNTYGGVGSLGTPIVRTDAAAIWATGQTWWQIPPVAKVEFTGEL 184

Query: 189 PQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFP 248
            +GV+GKD+IVALCG+FN D+VLNHAIEF GD + +LPID+RLTIANMTTEWGALSGLFP
Sbjct: 185 SEGVTGKDVIVALCGVFNQDEVLNHAIEFVGDGVKSLPIDYRLTIANMTTEWGALSGLFP 244

Query: 249 VDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           VD+T+ID+Y+ R+Q+L    H RIN  T+  L   AK   AD DA YAK LI+DL+T++ 
Sbjct: 245 VDQTVIDFYEGRMQRL-QQPHERINSDTVGKLAANAKEMAADSDAKYAKHLIVDLSTISP 303

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVA 368
            VSGPNSVKV++++ DL+QQDIKINKAYLVSCTNSRLSD+Q+AAD+V       + + +A
Sbjct: 304 CVSGPNSVKVASSLHDLAQQDIKINKAYLVSCTNSRLSDIQAAADIV-------RGHTIA 356

Query: 369 PGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISAT 428
            GVEFYVAAASS+++ DA  +GAW+ ++ AG  PLP+GCGPCIGLG GLLEPGEVGISAT
Sbjct: 357 DGVEFYVAAASSQVQQDAEAAGAWQTIIDAGAKPLPAGCGPCIGLGTGLLEPGEVGISAT 416

Query: 429 NRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVE 488
           NRNFKGRMGSKDALAYLASP VVAASA+LG+I  P E+ S S+I         ++     
Sbjct: 417 NRNFKGRMGSKDALAYLASPEVVAASAILGRIGGPEEI-SGSKI----AAPATLKRSTSV 471

Query: 489 EEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQV 548
              +++  A    V+I+ GFP+E +GEL+LC+ADNINTDGIYPGKYTYQDDVPKEKMAQV
Sbjct: 472 STSDSEDSATGAGVDIIPGFPQELTGELILCNADNINTDGIYPGKYTYQDDVPKEKMAQV 531

Query: 549 CMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSI 608
           CMENYD EF +K  PGDI++SG+NFGTGSSREQAATA+LA+G+ LVV+GSFGNIFSRNSI
Sbjct: 532 CMENYDGEFYSKTKPGDIIISGYNFGTGSSREQAATAILARGMQLVVAGSFGNIFSRNSI 591

Query: 609 NNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQK 668
           NNALLTLEIPALI KLR+KY G  KELT RTGWFLKWDV  A+V VT+   D  VI++QK
Sbjct: 592 NNALLTLEIPALIDKLRQKYAG-DKELTIRTGWFLKWDVPKAQVTVTDA--DNKVIMQQK 648

Query: 669 VGELGKNLQEIIVKGGLEGWVKSQL 693
           VGELG NLQ+IIVKGGLEGWVK+Q+
Sbjct: 649 VGELGTNLQDIIVKGGLEGWVKAQI 673
>ref|XP_717326.1| homoaconitase [Candida albicans SC5314]
 ref|XP_717250.1| homoaconitase [Candida albicans SC5314]
 sp|Q5A644|LYS4_CANAL Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|EAK98277.1| potential homoaconitase [Candida albicans SC5314]
 gb|EAK98354.1| potential homoaconitase [Candida albicans SC5314]
          Length = 684

 Score =  965 bits (2495), Expect = 0.0,   Method: Composition-based stats.
 Identities = 481/687 (70%), Positives = 564/687 (82%), Gaps = 14/687 (2%)

Query: 9   RSFHSSRAWLKGQNLTEKIVQSYAVNL-PEGKVVHSGDYVSIKPAHCMSHDNSWPVALKF 67
           RSF ++   L+GQNLTEKIVQ YAV L P  K V+SGDYV+IKPAHCMSHDNSWPVA KF
Sbjct: 6   RSFSTTTHLLRGQNLTEKIVQKYAVGLQPSSKKVYSGDYVTIKPAHCMSHDNSWPVATKF 65

Query: 68  MGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMI 127
           M LGA+K+K+  QIV TLDHD+QNKSE+NLTKY NIE FAK   ID YPAGRGIGHQIMI
Sbjct: 66  MNLGASKVKDNRQIVCTLDHDVQNKSEQNLTKYTNIEKFAKSQGIDFYPAGRGIGHQIMI 125

Query: 128 EEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQ 187
           EEGYAFPLN+TVASDSHSNTYGG+G+LGTPIVRTDAA+IWATGQTWWQIPPVA+VEL GQ
Sbjct: 126 EEGYAFPLNLTVASDSHSNTYGGIGALGTPIVRTDAASIWATGQTWWQIPPVAKVELIGQ 185

Query: 188 LPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG-DSLNALPIDHRLTIANMTTEWGALSGL 246
           LP+GV+GKDIIVALCG+FNND+VLNHAIEF G D+++ LPID+RLTIANMTTEWGALSGL
Sbjct: 186 LPKGVTGKDIIVALCGIFNNDEVLNHAIEFVGDDAISKLPIDYRLTIANMTTEWGALSGL 245

Query: 247 FPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATL 306
           FPVD+TL+++Y+NRL+KL   +HPRIN +TI  L        +D DA YAK L IDL++L
Sbjct: 246 FPVDETLVEFYQNRLKKLNKPDHPRINNQTIDQLINNKL--TSDNDAVYAKHLQIDLSSL 303

Query: 307 THYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNK 366
           + Y+SGPNSVK+SN++ DLSQQ+I INKAYLVSCTNSRLSD+Q+AAD++       K +K
Sbjct: 304 SPYISGPNSVKISNSLYDLSQQNIAINKAYLVSCTNSRLSDIQAAADII-------KGHK 356

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           V P VEFYVAAASS ++ DA +SGAW+ +L AG  PLP+GCGPCIGLG GLL+ GEVGIS
Sbjct: 357 VNPNVEFYVAAASSLVQKDAEQSGAWQTILDAGAKPLPAGCGPCIGLGTGLLKDGEVGIS 416

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPV 486
           ATNRNFKGRMGSKDALAYLASP VVAASAVLGKI  P E+          +   I     
Sbjct: 417 ATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGGPEELNGEPVKQAPRIIKSIETESN 476

Query: 487 VEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMA 546
              E  + +E    S++IL GFP+   GEL+LC+ADNINTDGIYPGKYTYQDD+ KE+MA
Sbjct: 477 SANEAESTSEEASGSIDILPGFPQSIEGELILCNADNINTDGIYPGKYTYQDDITKEQMA 536

Query: 547 QVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRN 606
           +VCMENYD++F +K  PGDI++SG+NFGTGSSREQAAT +LA+G+ L+V+GSFGNIFSRN
Sbjct: 537 KVCMENYDSQFYSKTKPGDIIISGYNFGTGSSREQAATCILARGMKLIVAGSFGNIFSRN 596

Query: 607 SINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILE 666
           SINNALLTLEIP LI KLR++Y+G   ELT RTGWFLKWDV  A+V V +G  D  +IL 
Sbjct: 597 SINNALLTLEIPDLINKLRQQYEGN-DELTIRTGWFLKWDVTKAQVTVVDG--DDNLILT 653

Query: 667 QKVGELGKNLQEIIVKGGLEGWVKSQL 693
           QKVGELG NLQ+IIVKGGLEGWVKS+L
Sbjct: 654 QKVGELGTNLQDIIVKGGLEGWVKSEL 680
>sp|Q2HZ33|LYS4_CANPA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|ABC94604.1| homoaconitase [Candida parapsilosis]
          Length = 688

 Score =  963 bits (2489), Expect = 0.0,   Method: Composition-based stats.
 Identities = 487/697 (69%), Positives = 561/697 (80%), Gaps = 31/697 (4%)

Query: 9   RSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFM 68
           R   +S     GQNLTEKIVQ YAVNLP  K+VH+GDYV+IKPAHCMSHDNSWPVA KFM
Sbjct: 7   RFISTSTPLRSGQNLTEKIVQKYAVNLPPNKLVHTGDYVTIKPAHCMSHDNSWPVATKFM 66

Query: 69  GLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIE 128
           GLGA ++K+  QIV TLDHD+QNK+EKNL KY NIE FAK+  ID YPAGRGIGHQIMIE
Sbjct: 67  GLGAKRVKDNRQIVCTLDHDVQNKTEKNLAKYANIERFAKEQGIDFYPAGRGIGHQIMIE 126

Query: 129 EGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQL 188
           EGYAFPLN+TVASDSHSNTYGG+GSLGTPIVRTDAA+IWAT QTWWQIPPVA+VELKG L
Sbjct: 127 EGYAFPLNLTVASDSHSNTYGGVGSLGTPIVRTDAASIWATVQTWWQIPPVAKVELKGNL 186

Query: 189 PQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFP 248
             GV+GKDIIVALCG+FNND+VLNHAIEF GD +  LPID+RLTIANMTTEWGALSGLFP
Sbjct: 187 QNGVTGKDIIVALCGVFNNDEVLNHAIEFVGDGVENLPIDYRLTIANMTTEWGALSGLFP 246

Query: 249 VDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           +D  LI++Y+ RLQKLG  NHPRIN  TI AL   +    +D+DA YAK L+IDL TL+ 
Sbjct: 247 IDDKLIEFYEGRLQKLGP-NHPRINKDTIEALRRGSL--ASDEDAKYAKHLVIDLNTLSP 303

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVA 368
           YVSGPNSVKVSN +  LSQ +I INKAYLVSCTNSRLSD+Q+AADV+       K +KV 
Sbjct: 304 YVSGPNSVKVSNPLSKLSQDNIAINKAYLVSCTNSRLSDIQAAADVL-------KGHKVH 356

Query: 369 PGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISAT 428
           P VEFYVAAASS ++ DA  +GAW+ ++ AG  PLP+GCGPCIGLG GLL+ GEVGISAT
Sbjct: 357 PNVEFYVAAASSLVQQDAEAAGAWQTIIDAGAKPLPAGCGPCIGLGTGLLKDGEVGISAT 416

Query: 429 NRNFKGRMGSKDALAYLASPAVVAASAVLGKISSP-----------AEVLSTSEIP-FSG 476
           NRNFKGRMGSKDALAYLASP VVAASAVLGKI +P            E++ + ++P  SG
Sbjct: 417 NRNFKGRMGSKDALAYLASPEVVAASAVLGKIGAPEEIDGKPVNASPEIVKSIDLPKSSG 476

Query: 477 VKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTY 536
                 E P+ E++ +      + SVE+L GFP+   GEL+LC+ADNINTDGIYPGKYTY
Sbjct: 477 NTGATSEEPISEDDTS------EASVEVLPGFPKSIQGELILCNADNINTDGIYPGKYTY 530

Query: 537 QDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVS 596
           QDD+ +E+MA+VCMENYD EF+TK    DI++SG+NFGTGSSREQAAT +LA+G+ LVV+
Sbjct: 531 QDDISREQMAEVCMENYDPEFKTKTKSDDIIISGYNFGTGSSREQAATCILARGMKLVVA 590

Query: 597 GSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTE 656
           GSFGNIFSRNSINNALLTLEIP LI+KLR KY G   ELT RTGWFLKWDV   K +VT 
Sbjct: 591 GSFGNIFSRNSINNALLTLEIPELIEKLRVKYDGV-NELTIRTGWFLKWDV--TKALVTV 647

Query: 657 GSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
             LDG VIL+QKVGELG NLQ+IIVKGGLEGWVKS+L
Sbjct: 648 ADLDGEVILQQKVGELGTNLQDIIVKGGLEGWVKSEL 684
>ref|XP_503471.1| hypothetical protein [Yarrowia lipolytica]
 sp|Q6C791|LYS4_YARLI Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAG79050.1| unnamed protein product [Yarrowia lipolytica CLIB122]
          Length = 687

 Score =  962 bits (2488), Expect = 0.0,   Method: Composition-based stats.
 Identities = 482/691 (69%), Positives = 555/691 (80%), Gaps = 17/691 (2%)

Query: 5   TTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA 64
           T   R + + R     QNLTEKIVQ YAV LPEGK V SGDYVSI+P+HCM+HDNSWPVA
Sbjct: 12  TLLVRRYSTKRI---PQNLTEKIVQRYAVGLPEGKQVQSGDYVSIRPSHCMTHDNSWPVA 68

Query: 65  LKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQ 124
            KF GLGA  +K+  Q+V TLDHD+QNKSEKNL KY NIENFA +  ID YPAGRGIGHQ
Sbjct: 69  TKFKGLGAKAVKDNRQVVMTLDHDVQNKSEKNLEKYANIENFAGEQGIDFYPAGRGIGHQ 128

Query: 125 IMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVEL 184
           +M+EEGYAFP N+TVASDSHSN YGG+G LGTPIVRTDAA++WATGQTWWQIPPVA+VEL
Sbjct: 129 VMVEEGYAFPYNLTVASDSHSNMYGGIGCLGTPIVRTDAASVWATGQTWWQIPPVARVEL 188

Query: 185 KGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALS 244
           KGQLP GV GKD+I+ALCG+FNND+VLNHAIEF GD +  L +D RLTIANMTTEWGAL+
Sbjct: 189 KGQLPAGVFGKDVIIALCGIFNNDEVLNHAIEFVGDGVEHLSVDERLTIANMTTEWGALT 248

Query: 245 GLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLA 304
           GLFPVD+TL  WY+ RL +L    H R+N  T+ AL++     +AD DA YAK L IDL+
Sbjct: 249 GLFPVDETLRQWYEYRLTRL-PQPHARVNDGTVAALKDAV---QADTDAKYAKNLTIDLS 304

Query: 305 TLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKV 364
           TL+ ++SGPNSVKV N++ DLS QDIKINKAYLVSCTNSRLSD+++AA+V+       K 
Sbjct: 305 TLSPFLSGPNSVKVYNSLADLSAQDIKINKAYLVSCTNSRLSDIEAAANVI-------KN 357

Query: 365 NKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVG 424
           NKVA GVEFYVAAASS ++ DA  SGAW+ L+ AG  PLP+GCGPCIGLG GLLE GEVG
Sbjct: 358 NKVAEGVEFYVAAASSFVQKDAEASGAWQTLINAGAKPLPAGCGPCIGLGTGLLEDGEVG 417

Query: 425 ISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEI--I 482
           ISATNRNFKGRMGSKDALAYLASP VVAASAVLGKI  P EV  +      GV + I   
Sbjct: 418 ISATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGFPEEVYGSPVPGAKGVSSSISVT 477

Query: 483 ENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPK 542
           E    E +  A    P  S  +L+GFP + +GELVLCDADNINTDGIYPGKYTYQDDVP+
Sbjct: 478 EAVEAEADAEAAESDPAPSGGVLDGFPAQITGELVLCDADNINTDGIYPGKYTYQDDVPR 537

Query: 543 EKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNI 602
           EKMA+VCMENYD +F +K   GDI+VSGFNFGTGSSREQAAT +LA+ + LV++GSFGNI
Sbjct: 538 EKMAEVCMENYDPDFGSKTGAGDIIVSGFNFGTGSSREQAATCILARDMQLVIAGSFGNI 597

Query: 603 FSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGP 662
           FSRNSINNALLTLEIPALI KLR++Y+G P ELTRRTGWF  WDV  A V VT+G  +GP
Sbjct: 598 FSRNSINNALLTLEIPALINKLRKRYEGQPAELTRRTGWFATWDVPAATVTVTDGK-NGP 656

Query: 663 VILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           VIL+QKVGELG+NLQEIIVKGGLEGWVK+QL
Sbjct: 657 VILKQKVGELGQNLQEIIVKGGLEGWVKAQL 687
>ref|XP_460673.1| hypothetical protein DEHA0F08019g [Debaryomyces hansenii CBS767]
 sp|Q6BM98|LYS4_DEBHA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAG89007.1| unnamed protein product [Debaryomyces hansenii CBS767]
          Length = 688

 Score =  955 bits (2468), Expect = 0.0,   Method: Composition-based stats.
 Identities = 478/689 (69%), Positives = 559/689 (81%), Gaps = 18/689 (2%)

Query: 6   TFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVAL 65
           T  R   SS    +GQNLTEKIVQ YAV L + K V SGDYV+IKPAHCMSHDNSWPVA 
Sbjct: 15  TGARCLSSSSILYRGQNLTEKIVQKYAVGLADDKKVFSGDYVTIKPAHCMSHDNSWPVAT 74

Query: 66  KFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQI 125
           KFMGLGAT + +  QIV TLDHD+QNKSEKNL KY NIENFAK+  ID YPAGRGIGHQI
Sbjct: 75  KFMGLGATNVHDNRQIVCTLDHDVQNKSEKNLEKYHNIENFAKEQGIDFYPAGRGIGHQI 134

Query: 126 MIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELK 185
           MIEEGYA+PLN+TVASDSHSNTYGG+GSLGTPIVRTDAA+IWATGQTWWQIPPVA+VEL 
Sbjct: 135 MIEEGYAYPLNLTVASDSHSNTYGGIGSLGTPIVRTDAASIWATGQTWWQIPPVAKVELV 194

Query: 186 GQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSG 245
           GQLP+G +GKDIIVALCG+FNND+VLNHAIEFTG+ +  L +D+RLTIANMTTEWGALSG
Sbjct: 195 GQLPKGATGKDIIVALCGIFNNDEVLNHAIEFTGEGVKNLSVDYRLTIANMTTEWGALSG 254

Query: 246 LFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLAT 305
           LFPVD+TL+++Y  R++KL    HPR+N  T++ L E      +D DA YAK L++DL++
Sbjct: 255 LFPVDETLVNFYDERVKKL-PQPHPRVNENTVKNLSENKV--NSDNDAVYAKHLVVDLSS 311

Query: 306 LTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVN 365
           L+ Y+SGPNSVKVS ++ DLS+Q+IKINKAYLVSCTNSRLSD+++AAD++       K +
Sbjct: 312 LSPYISGPNSVKVSTSLHDLSKQNIKINKAYLVSCTNSRLSDIKAAADII-------KGH 364

Query: 366 KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGI 425
           KVA GVEFYVAAASS ++ DA   GAW+ ++ AG  PLP+GCGPCIGLG GLLE GEVGI
Sbjct: 365 KVAEGVEFYVAAASSNVQKDAEAIGAWQDIIDAGAKPLPAGCGPCIGLGTGLLEDGEVGI 424

Query: 426 SATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENP 485
           SATNRNFKGRMGSKDALAYLASP VVAASAVLGKI  P E L  + +P      EI+ + 
Sbjct: 425 SATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGGPEE-LQGNPVP---TNPEIVRSI 480

Query: 486 VVEEEV-NAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEK 544
              E       +A   SV++L+GFP+   GEL+LCDADNINTDGIYPGKYTYQDD+P+ K
Sbjct: 481 TSNESTETVDPDASGSSVDVLDGFPQSIEGELILCDADNINTDGIYPGKYTYQDDIPRSK 540

Query: 545 MAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFS 604
           MA+VCMENYD+EF+ K   GDI++SG+NFGTGSSREQAATA+LA+ + LVV+GSFGNIFS
Sbjct: 541 MAEVCMENYDSEFKQKTKAGDIIISGYNFGTGSSREQAATAILARDMKLVVAGSFGNIFS 600

Query: 605 RNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVI 664
           RNSINNALLTLEIPALI KLREKY     ELT RTGWFLKWDV   +V V++   +G +I
Sbjct: 601 RNSINNALLTLEIPALINKLREKY-AQSNELTIRTGWFLKWDVTKNQVTVSDS--EGNLI 657

Query: 665 LEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           L QKVGELG NLQ+IIVKGGLEGWVK+QL
Sbjct: 658 LTQKVGELGTNLQDIIVKGGLEGWVKAQL 686
>ref|XP_001523113.1| homoaconitase, mitochondrial precursor [Lodderomyces elongisporus
           NRRL YB-4239]
 gb|EDK47478.1| homoaconitase, mitochondrial precursor [Lodderomyces elongisporus
           NRRL YB-4239]
          Length = 688

 Score =  937 bits (2422), Expect = 0.0,   Method: Composition-based stats.
 Identities = 474/698 (67%), Positives = 560/698 (80%), Gaps = 25/698 (3%)

Query: 3   RSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLP------EGKVVHSGDYVSIKPAHCMS 56
           R +   R F S     +GQNLTEKIVQ +A+ LP      + K+VHSGDYV+IKP HCMS
Sbjct: 4   RLSNAVRCFSSPAHLRQGQNLTEKIVQRFAI-LPATADGSQQKLVHSGDYVTIKPQHCMS 62

Query: 57  HDNSWPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYP 116
           HDNSWPVA KFMGLGA K+K+  QIV TLDHD+QNKSE NL KY+NI  FAK   ID YP
Sbjct: 63  HDNSWPVATKFMGLGAKKVKDNRQIVNTLDHDVQNKSEANLKKYENIAKFAKLQGIDFYP 122

Query: 117 AGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQI 176
           AGRGIGHQIMIEEGYAFP N+TVASDSHSNTYGG+ SLGTPIVRTDAA+IWATGQTWWQI
Sbjct: 123 AGRGIGHQIMIEEGYAFPGNLTVASDSHSNTYGGVASLGTPIVRTDAASIWATGQTWWQI 182

Query: 177 PPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANM 236
           PPVA+VELKG+L +GV+GKDIIVALCG+FNND+VLNHAIEF GD +  L ID+RLTIANM
Sbjct: 183 PPVAKVELKGKLAKGVTGKDIIVALCGVFNNDEVLNHAIEFVGDGVEQLSIDYRLTIANM 242

Query: 237 TTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYA 296
           TTEWGALSGLFPVD  L+ WY+ RL+++G  +HPRIN KT+  L +     K+D DA YA
Sbjct: 243 TTEWGALSGLFPVDDKLVQWYQQRLERVGP-DHPRINKKTVGELMQNQI--KSDADAKYA 299

Query: 297 KKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVC 356
           K L+IDL+TL  YVSGPNSVK+SN++  LSQ +I INKAYLVSCTNSRLSD+++AA ++ 
Sbjct: 300 KHLVIDLSTLAPYVSGPNSVKISNSLTKLSQDNIAINKAYLVSCTNSRLSDIEAAAGIL- 358

Query: 357 PTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAG 416
                 K +KV P VEFYVAAASS ++ DA   GAW+ +L AG  PLP+GCGPCIGLG+G
Sbjct: 359 ------KGHKVHPNVEFYVAAASSLVQKDAEALGAWQTILDAGAKPLPAGCGPCIGLGSG 412

Query: 417 LLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSG 476
           LL+ GEVGISATNRNFKGRMGSKDALAYLASP VVAASA+LG+I +P EV      P + 
Sbjct: 413 LLKDGEVGISATNRNFKGRMGSKDALAYLASPEVVAASAILGRIGAPEEV---DGAPVNA 469

Query: 477 VKTEIIENPVVEEEVN-AQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYT 535
              EI+++  +E+ +  A  +A   ++++LEGFP+   GEL+LC+ADNINTDGIYPGKYT
Sbjct: 470 -SPEIVKSIEIEDSLAPAADDASSGAIDVLEGFPKSIEGELILCNADNINTDGIYPGKYT 528

Query: 536 YQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVV 595
           YQDD+ KE+MA+VCMENYD EF+TK    DI++SG+NFGTGSSREQAAT +LA+G+ LVV
Sbjct: 529 YQDDISKEQMAEVCMENYDPEFKTKTRSDDIIISGYNFGTGSSREQAATCILARGMKLVV 588

Query: 596 SGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVT 655
           +GSFGNIFSRN+INNALLTLEIP LI KLREKYQG+  ELT RTGWFLKWDV  A V V 
Sbjct: 589 AGSFGNIFSRNAINNALLTLEIPDLINKLREKYQGS-NELTIRTGWFLKWDVTTATVTVA 647

Query: 656 EGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           +   D  VIL+QKVGELG NLQ+IIVKGGLEGWVK++L
Sbjct: 648 DS--DANVILKQKVGELGTNLQDIIVKGGLEGWVKAEL 683
>ref|NP_982841.1| ABL106Cp [Ashbya gossypii ATCC 10895]
 sp|Q75DX9|LYS4_ASHGO Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|AAS50665.1| ABL106Cp [Ashbya gossypii ATCC 10895]
          Length = 686

 Score =  887 bits (2293), Expect = 0.0,   Method: Composition-based stats.
 Identities = 458/692 (66%), Positives = 545/692 (78%), Gaps = 10/692 (1%)

Query: 2   LRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSW 61
           +R     R F +SRA + GQN TEKIVQ++AV L  G  V SGDYVSI+PAHCMSHDNSW
Sbjct: 1   MRVVRCVRRFSASRA-VSGQNTTEKIVQAHAVGLRPGHRVASGDYVSIRPAHCMSHDNSW 59

Query: 62  PVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGI 121
           PVALKFMGLGAT++ +  Q+V TLDHD+QN+SEKNL KY+NIE FA +  +D YPA RGI
Sbjct: 60  PVALKFMGLGATRVHDARQVVCTLDHDVQNRSEKNLAKYRNIELFAAQQGVDFYPARRGI 119

Query: 122 GHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQ 181
           GHQIM+EEGYAFPL +TVASDSHSNTYGG+G+LGTP+VRTDAAAIWATGQTWWQ+PPVA+
Sbjct: 120 GHQIMVEEGYAFPLGLTVASDSHSNTYGGVGALGTPVVRTDAAAIWATGQTWWQVPPVAR 179

Query: 182 VELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWG 241
           VEL G+LP GVSGKD IVALCG+F  D+VLNHA+EF G  +  L ++ RLT+ANMTTEWG
Sbjct: 180 VELTGELPAGVSGKDAIVALCGVFGRDEVLNHAVEFAGPGVARLTVEQRLTVANMTTEWG 239

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLII 301
           ALSGLFPVD  L+DWY+ ++ +     H R+    + AL E+A   + D DA YAK+L +
Sbjct: 240 ALSGLFPVDGVLLDWYREQVAR-APAGHARLTAARVDALAERAAAMQPDTDARYAKQLTL 298

Query: 302 DLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDL 361
           DL++LTHYVSGPNSVKV+  + +L+ Q ++I+KAYL+SCTN RL DL++AA V+   G+ 
Sbjct: 299 DLSSLTHYVSGPNSVKVARPIAELAPQQLRIDKAYLLSCTNGRLEDLEAAAAVLRADGN- 357

Query: 362 NKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPG 421
             V +VAPGVEFY+AAAS+E+EA AR  G W+ LL AGCIPLPSGCGPCIGLG GLLE G
Sbjct: 358 --VRQVAPGVEFYIAAASAEVEAQARARGTWDVLLSAGCIPLPSGCGPCIGLGKGLLEAG 415

Query: 422 EVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEI 481
           EVGISATNRNF+GRMGSKDA AYLASPAVVAASAVLG+I++P EVL  S      V+   
Sbjct: 416 EVGISATNRNFRGRMGSKDAEAYLASPAVVAASAVLGRIAAPCEVLGLSPPAAPAVRAS- 474

Query: 482 IENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVP 541
               V +    A  +    +VE+L GFPR  +GELVLCDADNINTDGIYPGKYTY+DD+P
Sbjct: 475 ----VAQCGAPAAADGAAAAVEVLPGFPRAITGELVLCDADNINTDGIYPGKYTYEDDIP 530

Query: 542 KEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGN 601
           +E MA+VCMENYD +F+  VH GDIVV G+NFGTGSSREQAATALLAKG+ LVV+GSF N
Sbjct: 531 RETMARVCMENYDLDFQHNVHAGDIVVGGYNFGTGSSREQAATALLAKGVPLVVAGSFSN 590

Query: 602 IFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDG 661
            FSRN+INNALLTLE+PAL++ LRE+Y  AP + TRRTG FL WDVA A V VT GS  G
Sbjct: 591 TFSRNAINNALLTLELPALLQLLRERYADAPSQATRRTGVFLTWDVAAATVTVTVGSPTG 650

Query: 662 PVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
             +L Q+VGE   NLQEIIVKGGLEGWVK  L
Sbjct: 651 ERVLHQRVGEFSANLQEIIVKGGLEGWVKHAL 682
>ref|NP_593437.1| homoaconitate hydratase Lys2 [Schizosaccharomyces pombe]
 sp|Q9UT74|LYS4_SCHPO Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAB52279.1| homoaconitate hydratase Lys2 [Schizosaccharomyces pombe]
          Length = 721

 Score =  828 bits (2140), Expect = 0.0,   Method: Composition-based stats.
 Identities = 432/673 (64%), Positives = 521/673 (77%), Gaps = 16/673 (2%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q +TEKIVQ +A N+PE K V SGDYV+IKP HCMSHDNSWPVALKFMG+GA K+ +  Q
Sbjct: 61  QTITEKIVQKFAQNIPENKYVRSGDYVTIKPKHCMSHDNSWPVALKFMGIGAKKVFDNRQ 120

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKSE NL KYKNIE+FAK   ID YPAGRGIGHQIM+E+GYA P +M VA
Sbjct: 121 IVCTLDHDVQNKSEANLRKYKNIESFAKGQGIDFYPAGRGIGHQIMVEQGYAMPGSMAVA 180

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSNTYGG+G LGTPIVRTDAAAIWATGQTWWQIPP+A+V L GQLP+G+SGKDIIV+
Sbjct: 181 SDSHSNTYGGVGCLGTPIVRTDAAAIWATGQTWWQIPPIARVNLVGQLPKGLSGKDIIVS 240

Query: 201 LCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNR 260
           LCG FN+D+VLNHAIEF G+ LN+L I+ RLTIANMTTEWGALSGLFP D+ L+ WY++R
Sbjct: 241 LCGAFNHDEVLNHAIEFYGEGLNSLSIESRLTIANMTTEWGALSGLFPTDEKLLAWYEDR 300

Query: 261 LQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVSN 320
           L+ LG  NHPR+N +T+ A+  KA    AD+ A YAK LI+DL+TL+  VSGPNSVKV N
Sbjct: 301 LKFLGP-NHPRVNRETLDAI--KASPILADEGAFYAKHLILDLSTLSPAVSGPNSVKVYN 357

Query: 321 TVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASS 380
           +   L ++DI I KAYLVSCTN RLSD+  AA+ V       K  KVA GVEFYV AASS
Sbjct: 358 SAATLEKKDILIKKAYLVSCTNGRLSDIHDAAETV-------KGKKVADGVEFYVGAASS 410

Query: 381 EIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKD 440
           E+EA A+K+G W+ L+ +G   LP+GCGPCIGLG GLL+ GEVGISATNRNFKGRMGS++
Sbjct: 411 EVEAAAQKNGDWQTLIDSGARTLPAGCGPCIGLGTGLLKDGEVGISATNRNFKGRMGSRE 470

Query: 441 ALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEAPKQ 500
           ALAYLASPAVVAASA+ GKI +P E    +    S V  +I +    +    + TEA   
Sbjct: 471 ALAYLASPAVVAASAIAGKIVAP-EGFKNAVSLVSAV--DITDKVNKQTASKSSTEAVDS 527

Query: 501 SVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTK 560
              I++GFP   +GE+V CDADN+NTDGIYPG+YTY+DD+ KE+MA+VCMENYD+EF  K
Sbjct: 528 ETAIIDGFPSIVAGEIVFCDADNLNTDGIYPGRYTYRDDITKEEMAKVCMENYDSEFGKK 587

Query: 561 VHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPAL 620
               DI+VSGFNFGTGSSREQAATA+L++GI LVV GSF +IF RNSINNALL +++P L
Sbjct: 588 TKKDDILVSGFNFGTGSSREQAATAILSRGIPLVVGGSFSDIFKRNSINNALLAIQLPDL 647

Query: 621 IKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEII 680
           ++KLR  +    KELTRRTGW LKWDV  + V VT         +  K+GELG ++Q + 
Sbjct: 648 VQKLRTAFANESKELTRRTGWHLKWDVRKSTVTVTTSDNKE---MSWKIGELGNSVQSLF 704

Query: 681 VKGGLEGWVKSQL 693
           V+GGLEGWVK ++
Sbjct: 705 VRGGLEGWVKHEI 717
>ref|XP_664125.1| LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate
           hydratase) [Aspergillus nidulans FGSC A4]
 gb|EAA57861.1| LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate
           hydratase) [Aspergillus nidulans FGSC A4]
          Length = 776

 Score =  811 bits (2096), Expect = 0.0,   Method: Composition-based stats.
 Identities = 428/735 (58%), Positives = 515/735 (70%), Gaps = 56/735 (7%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S     + +SS+A    Q LTEKIVQ Y+V LP+GK V SGDYV+I+P  CM+HDNSWP 
Sbjct: 51  SAALFSALNSSKA--VPQTLTEKIVQKYSVGLPQGKFVKSGDYVTIQPHRCMTHDNSWPC 108

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GA+++ NP QIV TLDHD+QNKS+KNL KY+ IE FA +H ++ YPAGRGIGH
Sbjct: 109 ALKFMSIGASRLHNPDQIVMTLDHDVQNKSDKNLKKYRQIEEFATQHGVEFYPAGRGIGH 168

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIMIEEG+A+P  + VASDSHSN YGG+G LGTPIVRTDAA++WATG+TWWQIPPVA+V 
Sbjct: 169 QIMIEEGFAWPGTLAVASDSHSNMYGGVGCLGTPIVRTDAASVWATGKTWWQIPPVAKVT 228

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
            KG LP GV+GKD+IVALCGLFN D VLNHAIEFTG  +++ +L +D RLTIANMTTEWG
Sbjct: 229 FKGVLPPGVTGKDVIVALCGLFNKDDVLNHAIEFTGSEETMRSLSVDTRLTIANMTTEWG 288

Query: 242 ALSGLFPVDKTLIDWYKNR--LQKLGTNNHPRINPKTIR----ALEEKAKIP-KADKDAH 294
           ALSGLFP+D  L  W + +     +G  + P       R     LE+  + P  ADK A 
Sbjct: 289 ALSGLFPIDSVLKGWLRGKATTAAMGLADGPFKTRAAERFTHPLLEQLFENPLTADKGAK 348

Query: 295 YAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADV 354
           YAK+L +DL++L+ YVSGPNSVKV+  +++L  Q+IK++KAYLVSCTNSR SD+ +AA V
Sbjct: 349 YAKELFLDLSSLSPYVSGPNSVKVATPLKELEAQNIKVDKAYLVSCTNSRASDIAAAAKV 408

Query: 355 VCPTGDLN--KVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIG 412
                + N  K+ K+A GV+FY+AAAS   +  A  +G W+ LL+AG   LP+GCGPCIG
Sbjct: 409 FKEAAEKNGGKIPKIADGVKFYIAAASIPEQLAAEGNGDWQTLLEAGATQLPAGCGPCIG 468

Query: 413 LGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPA-------- 464
           +G GLLEPGEVGISA+NRNFKGRMGS +A AYL SP VVAASA+ GK+S P         
Sbjct: 469 MGQGLLEPGEVGISASNRNFKGRMGSTEAKAYLGSPEVVAASALSGKLSGPGWYQTPEGW 528

Query: 465 ---------------EVLSTSE-----------IPFSGVKTEIIENPVVEEEVNAQTEAP 498
                           +L+  E           +   G K    E P VEE     T   
Sbjct: 529 TEVIRGEGDGIREEDRMLTNEEALEKIIGQLDDLVADGEKRFASETPAVEESEQGLT--- 585

Query: 499 KQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFR 558
               EI  GFP   SGELV CDADN+NTDGIYPGKYTYQDDVP E MA+VCMENYD EF 
Sbjct: 586 ----EIYPGFPERVSGELVFCDADNVNTDGIYPGKYTYQDDVPPETMARVCMENYDPEFS 641

Query: 559 TKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIP 618
           T    GDI+VSGFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P
Sbjct: 642 TTAKEGDILVSGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVP 701

Query: 619 ALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQE 678
            L+ +LRE +    K LTRRTGW L WDV  +++ V EG   GP     KVGEL  N+QE
Sbjct: 702 RLVNRLRETFGSGDKVLTRRTGWTLTWDVRKSQIEVQEGP-GGPK-WTHKVGELPPNVQE 759

Query: 679 IIVKGGLEGWVKSQL 693
           II KGGLE WVK+ +
Sbjct: 760 IIAKGGLEKWVKNAI 774
>ref|XP_001911427.1| unnamed protein product [Podospora anserina]
 emb|CAP73252.1| unnamed protein product [Podospora anserina]
          Length = 781

 Score =  810 bits (2093), Expect = 0.0,   Method: Composition-based stats.
 Identities = 424/715 (59%), Positives = 513/715 (71%), Gaps = 49/715 (6%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ Y+V L  GK V SGDYV++ P HCM+HDNSWPVA+KFM +GA+KI +  Q
Sbjct: 72  QTLTEKIVQRYSVGLAPGKTVKSGDYVTLAPHHCMTHDNSWPVAMKFMSIGASKIHDNRQ 131

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QNKSE NL KY+ IE FA KH +D YPAGRGIGHQIM+EEGYA+P  +TVA
Sbjct: 132 VVMTLDHDVQNKSEANLKKYRQIEEFAGKHGVDFYPAGRGIGHQIMVEEGYAWPGTVTVA 191

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V L G LP GV+GKD+IVA
Sbjct: 192 SDSHSNMYGGVGCLGTPMVRTDAASIWATGRTWWQIPPIAKVTLTGILPPGVTGKDVIVA 251

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLFNND VLNHAIEFTG  +++ +L ID RL IANMTTEWGALSGLFP+D  L  W +
Sbjct: 252 LCGLFNNDDVLNHAIEFTGSEETMRSLSIDDRLAIANMTTEWGALSGLFPIDSVLQQWLR 311

Query: 259 NRLQKLGTNNHPRINPKTIRALEEKAKIP-------KADKDAHYAKKLIIDLATLTHYVS 311
            +            NP+  +      KI        +AD  A YAK L ++L+TL+ +V+
Sbjct: 312 AK-----ATTAAMFNPEAAKGKFTHEKIDDLINNQLRADPGATYAKSLYLNLSTLSPFVA 366

Query: 312 GPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGV 371
           GPNSVKV+  ++DL  QDIK+NKAYLVSCTNSR SD+ +AA+V         + KVA GV
Sbjct: 367 GPNSVKVATPLKDLEAQDIKLNKAYLVSCTNSRASDIAAAANVFREVAKDGVIPKVAEGV 426

Query: 372 EFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRN 431
           +FY+AAAS+  +A A ++G W+ LL AG  PLPSGCGPCIGLG GLLEPGEVGISA+NRN
Sbjct: 427 KFYIAAASTLEQAAAEEAGDWQVLLAAGAEPLPSGCGPCIGLGTGLLEPGEVGISASNRN 486

Query: 432 FKGRMGSKDALAYLASPAVVAASAVLGKISSPA---EVLSTSEIPFSGVKTEIIENPV-- 486
           FKGRMGS DA AYLASP VVAASA+ GKI+ P    +     ++       +++++    
Sbjct: 487 FKGRMGSTDAKAYLASPEVVAASALKGKIAGPGWYQKPEGVEKVIIGEGNGDVVQDKAMS 546

Query: 487 VEEEVN---AQTEAPKQS----------------------VEILEGFPREFSGELVLCDA 521
           +EE ++   AQ ++   S                       EIL GFP +  GE+V CDA
Sbjct: 547 IEEALDKLIAQADSMIASAEKEFSGDEAAAAESAAEAETLTEILPGFPEKIEGEIVFCDA 606

Query: 522 DNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQ 581
           DNINTDGIYPGKYTYQD+V  EKMA+VCMENYD EF      GDI+VSGFNFG GSSREQ
Sbjct: 607 DNINTDGIYPGKYTYQDNVTTEKMAEVCMENYDKEFGQVAKEGDILVSGFNFGCGSSREQ 666

Query: 582 AATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQG---APKELTRR 638
           AATA+LAK I LVVSGSFGNIFSRNSINNAL+ +E+P L+++LRE ++      K LTRR
Sbjct: 667 AATAILAKKIPLVVSGSFGNIFSRNSINNALMGVEVPRLVQRLRETFKADGEGNKVLTRR 726

Query: 639 TGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           TGW L WDV  +KV VTEG  +G     QKVGEL  N+QEII +GGLE WVKSQ+
Sbjct: 727 TGWKLVWDVRRSKVTVTEG--EGGQQWSQKVGELPPNVQEIIARGGLEKWVKSQI 779
>sp|Q92412|LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAA67943.1| homoaconitase [Emericella nidulans]
          Length = 775

 Score =  806 bits (2081), Expect = 0.0,   Method: Composition-based stats.
 Identities = 427/735 (58%), Positives = 514/735 (69%), Gaps = 57/735 (7%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S     + +SS+A    Q LTEKIVQ Y+V LP+GK V SGDYV+I+P  CM+HDNSWP 
Sbjct: 51  SAALFSALNSSKA--VPQTLTEKIVQKYSVGLPQGKFVKSGDYVTIQPHRCMTHDNSWPC 108

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GA+++ NP QIV TLDHD+QNKS+KNL KY+ IE FA +H ++ YPAGRGIGH
Sbjct: 109 ALKFMSIGASRLHNPDQIVMTLDHDVQNKSDKNLKKYRQIEEFATQHGVEFYPAGRGIGH 168

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIMIEEG+A+P  + VASDSHSN YGG+G LGTPIVRTDAA++WATG+TWWQIPPVA+V 
Sbjct: 169 QIMIEEGFAWPGTLAVASDSHSNMYGGVGCLGTPIVRTDAASVWATGKTWWQIPPVAKVT 228

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
            KG LP GV+GKD+IVALCGLFN D VLNHAIEFTG  +++ +L +D RLTIANMTTEWG
Sbjct: 229 FKGVLPPGVTGKDVIVALCGLFNKDDVLNHAIEFTGSEETMRSLSVDTRLTIANMTTEWG 288

Query: 242 ALSGLFPVDKTLIDWYKNR--LQKLGTNNHPRINPKTIR----ALEEKAKIP-KADKDAH 294
           ALSGLFP+D  L  W + +     +G  + P       R     LE+  + P  ADK A 
Sbjct: 289 ALSGLFPIDSVLKGWLRGKATTAAMGLADGPFKTRAAERFTHPLLEQLFENPLTADKGAK 348

Query: 295 YAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADV 354
           YAK+L +DL++L+ YVSGPNSVKV+  +++L  Q+IK++KAYLVSCTNSR SD+ +AA V
Sbjct: 349 YAKELFLDLSSLSPYVSGPNSVKVATPLKELEAQNIKVDKAYLVSCTNSRASDIAAAAKV 408

Query: 355 VCPTGDLN--KVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIG 412
                + N  K+ K+  GV+FY+AAAS   +  A  +G W+ LL+AG   LP+GCGPCIG
Sbjct: 409 FKEAAEKNGGKIPKIH-GVKFYIAAASIPEQLAAEGNGDWQTLLEAGATQLPAGCGPCIG 467

Query: 413 LGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPA-------- 464
           +G GLLEPGEVGISA+NRNFKGRMGS +A AYL SP VVAASA+ GK+S P         
Sbjct: 468 MGQGLLEPGEVGISASNRNFKGRMGSTEAKAYLGSPEVVAASALSGKLSGPGWYQTPEGW 527

Query: 465 ---------------EVLSTSE-----------IPFSGVKTEIIENPVVEEEVNAQTEAP 498
                           +L+  E           +   G K    E P VEE     T   
Sbjct: 528 TEVIRGEGDGIREEDRMLTNEEALEKIIGQLDDLVADGEKRFASETPAVEESEQGLT--- 584

Query: 499 KQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFR 558
               EI  GFP   SGELV CDADN+NTDGIYPGKYTYQDDVP E MA+VCMENYD EF 
Sbjct: 585 ----EIYPGFPERVSGELVFCDADNVNTDGIYPGKYTYQDDVPPETMARVCMENYDPEFS 640

Query: 559 TKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIP 618
           T    GDI+VSGFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P
Sbjct: 641 TTAKEGDILVSGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVP 700

Query: 619 ALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQE 678
            L+ +LRE +    K LTRRTGW L WDV  +++ V EG   GP     KVGEL  N+QE
Sbjct: 701 RLVNRLRETFGSGDKVLTRRTGWTLTWDVRKSQIEVQEGP-GGPK-WTHKVGELPPNVQE 758

Query: 679 IIVKGGLEGWVKSQL 693
           II KGGLE WVK+ +
Sbjct: 759 IIAKGGLEKWVKNAI 773
>ref|XP_001248868.1| hypothetical protein CIMG_02639 [Coccidioides immitis RS]
 gb|EAS37285.1| hypothetical protein CIMG_02639 [Coccidioides immitis RS]
          Length = 801

 Score =  802 bits (2072), Expect = 0.0,   Method: Composition-based stats.
 Identities = 416/712 (58%), Positives = 513/712 (72%), Gaps = 43/712 (6%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ Y+V LP+ K V SGDYV+I P   M+HDNSWPVALKFM +GA+K+ +P+Q
Sbjct: 92  QTLTEKIVQRYSVGLPKDKYVKSGDYVTISPHRVMTHDNSWPVALKFMSIGASKLNDPNQ 151

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKSEKNL KY+ IE FAK H +D YPAGRGIGHQIM+EEGYA+P  + VA
Sbjct: 152 IVMTLDHDVQNKSEKNLKKYEQIETFAKTHGVDFYPAGRGIGHQIMVEEGYAWPGTLVVA 211

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V  +G LP+GV+GKD+IVA
Sbjct: 212 SDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVTFRGVLPKGVTGKDVIVA 271

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLF+ D VLNHAIEFTG  +++ ++ ID RLTIANMTTEWGALSGLFPVD  L  W +
Sbjct: 272 LCGLFDKDDVLNHAIEFTGSEETMRSIHIDDRLTIANMTTEWGALSGLFPVDSMLKGWLR 331

Query: 259 NR----------LQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           ++          + +L ++   R     +  L E+  +  ADK A YAK+L +DL+TL+ 
Sbjct: 332 SKATTAAMWGSTVPELQSSAAERFKHAALDQLFEEPLV--ADKGAKYAKELFLDLSTLSP 389

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN--KVNK 366
           YV+GPNSVKV+  +++L  Q+IK+NKAYLVSCTNSR SD+ +AA V     + N  K+ K
Sbjct: 390 YVAGPNSVKVATPLKELESQNIKVNKAYLVSCTNSRASDIAAAAKVFKEAAEKNGGKIPK 449

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           +A GV+FY+AAAS   +  A ++G W+ LL+AG  PLP+GCGPCIGLG GLLEPGEVGIS
Sbjct: 450 IADGVKFYIAAASIPEQRAAEEAGDWQALLEAGAEPLPAGCGPCIGLGTGLLEPGEVGIS 509

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLS----TSEIPFSGVKTEII 482
           ATNRNFKGRMGS +A AYL+SP VVAASA+ G IS P         T  +   G   E+I
Sbjct: 510 ATNRNFKGRMGSTEAKAYLSSPEVVAASALSGTISGPGWYEKPEGWTGVVRGEGDGNEMI 569

Query: 483 ENPVVEEEVNAQTEAPKQS------------------VEILEGFPREFSGELVLCDADNI 524
                 E+V  Q ++  +                    E+  GFP   SGE+V CDADNI
Sbjct: 570 TAEQALEKVIGQLDSMVEDAEKLFASEESNSSGEEGLTEVYPGFPERVSGEIVFCDADNI 629

Query: 525 NTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAAT 584
           NTDGIYPGKYTYQD++P E+M + CMENYD +F      GDI+V+G+NFG GSSREQAAT
Sbjct: 630 NTDGIYPGKYTYQDNIPYEQMGEYCMENYDTQFGKVAKAGDILVTGYNFGCGSSREQAAT 689

Query: 585 ALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKY---QGAPKELTRRTGW 641
           A+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P LI +LRE +   +   K+LTRRTGW
Sbjct: 690 AILAKQIPLVVSGSFGNIFSRNSINNALMGLEVPRLITRLRETFGSDKTDSKQLTRRTGW 749

Query: 642 FLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            L WDV  +++ + EG  DGP    QKVGEL  N+QEII  GGLE WVK+ +
Sbjct: 750 TLTWDVRRSQIEIQEGP-DGPK-WTQKVGELPPNVQEIIALGGLEKWVKNSI 799
>ref|XP_958836.1| homoaconitase, mitochondrial precursor [Neurospora crassa OR74A]
 sp|Q870W1|LYS4_NEUCR Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|EAA29600.1| homoaconitase, mitochondrial precursor [Neurospora crassa OR74A]
 emb|CAD71225.1| probable homoaconitase precursor [Neurospora crassa]
          Length = 784

 Score =  801 bits (2068), Expect = 0.0,   Method: Composition-based stats.
 Identities = 424/721 (58%), Positives = 512/721 (71%), Gaps = 61/721 (8%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ Y+V L  GK V SGDYV+++P HCM+HDNSWPVA+KFM +GA+KI +  Q
Sbjct: 75  QTLTEKIVQRYSVGLAPGKKVKSGDYVTLQPHHCMTHDNSWPVAMKFMSIGASKIHDNRQ 134

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QNKSE NL KY+ IE FA  H +D YPAGRGIGHQIM+EEGYA+P  +TVA
Sbjct: 135 VVMTLDHDVQNKSEANLKKYRQIEEFANTHGVDFYPAGRGIGHQIMVEEGYAWPGTVTVA 194

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V   G LP GV+GKD+IVA
Sbjct: 195 SDSHSNMYGGVGCLGTPMVRTDAASIWATGKTWWQIPPIAKVTFTGLLPPGVTGKDVIVA 254

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLFNND VLNHAIEFTG  +++ ++P+D RLTIANMTTEWGALSGLFP+D  L  W +
Sbjct: 255 LCGLFNNDDVLNHAIEFTGAEETMRSIPVDDRLTIANMTTEWGALSGLFPIDAVLASWMR 314

Query: 259 NRLQKLGTNNHPRINPKT------IRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSG 312
            +   +    HP +  K       I AL E   +  AD  A YAK+L ++L+TL+ +V+G
Sbjct: 315 AK-ATVTAMEHPELGDKAKFTHAKIDALLENPLV--ADPGATYAKQLYLNLSTLSPFVAG 371

Query: 313 PNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNK--VNKVAPG 370
           PNSVK++  ++DL  Q++K++KAYLVSCTNSR SD+ +AA V       N   + KVAPG
Sbjct: 372 PNSVKIATPLKDLEAQNLKLDKAYLVSCTNSRASDIAAAARVFKDAAADNNGVIPKVAPG 431

Query: 371 VEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNR 430
           V+FY+AAAS   +  A  SG W+ LL AG  PLPSGCGPCIGLG GLLEPGE+GISA+NR
Sbjct: 432 VKFYIAAASLLEQKQAEDSGDWQVLLDAGAEPLPSGCGPCIGLGTGLLEPGEIGISASNR 491

Query: 431 NFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIE--NPVVE 488
           NFKGRMGS DA AYLASP VVAASA+ GKI+ P            GV+  II   N VVE
Sbjct: 492 NFKGRMGSTDAKAYLASPEVVAASALKGKIAGPGWYQKPE-----GVEKVIIGEGNGVVE 546

Query: 489 EEVNAQTE-------APKQSV-----------------------------EILEGFPREF 512
           ++     E       A  +S+                             EIL GFP   
Sbjct: 547 QDKAMSIEDALDKIIAEAESLIANAEAGLTPESTSSSSSSSSSSEEESLTEILPGFPEAI 606

Query: 513 SGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFN 572
           SGE++ CDADNINTDGIYPGKYTYQD++   KMA+VCMENYDA F +    GDI+V+GFN
Sbjct: 607 SGEIIFCDADNINTDGIYPGKYTYQDNITPAKMAEVCMENYDASFGSIARAGDILVTGFN 666

Query: 573 FGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAP 632
           FG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ +E+P L+++LRE++    
Sbjct: 667 FGCGSSREQAATAILAKQIPLVVSGSFGNIFSRNSINNALMGVEVPKLVQRLREEF--GD 724

Query: 633 KELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
           K  TRRTGW L WDV  +KVVV E S       EQKVGEL  N+QEII +GGLE WVKSQ
Sbjct: 725 KVATRRTGWKLTWDVRRSKVVVEEASGKK---WEQKVGELPPNVQEIIARGGLEKWVKSQ 781

Query: 693 L 693
           +
Sbjct: 782 I 782
>ref|XP_359935.2| hypothetical protein MGG_04842 [Magnaporthe grisea 70-15]
 gb|EDJ95590.1| hypothetical protein MGG_04842 [Magnaporthe grisea 70-15]
          Length = 776

 Score =  800 bits (2066), Expect = 0.0,   Method: Composition-based stats.
 Identities = 421/714 (58%), Positives = 508/714 (71%), Gaps = 49/714 (6%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ Y+V L  GK V SGDYV++ P HCM+HDNSWPVALKFM +GA+KI +  Q
Sbjct: 69  QTLTEKIVQRYSVGLAPGKKVKSGDYVTLSPHHCMTHDNSWPVALKFMSIGASKIHDNRQ 128

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QNKSE NL KY+ IE FAK H +D YPAGRGIGHQIM+EEGYA+P  +TVA
Sbjct: 129 VVMTLDHDVQNKSESNLKKYRQIEEFAKTHGVDFYPAGRGIGHQIMVEEGYAWPGTVTVA 188

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V L G LP GV+GKD+IVA
Sbjct: 189 SDSHSNMYGGVGCLGTPMVRTDAASIWATGKTWWQIPPIAKVTLTGVLPPGVTGKDVIVA 248

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLFNND+VLNHAIEFTG  +++ ++P+D RL IANMTTEWGAL+GLFP+D  L  W +
Sbjct: 249 LCGLFNNDEVLNHAIEFTGSEETMRSIPVDDRLAIANMTTEWGALAGLFPIDSVLQGWLR 308

Query: 259 NRLQKLGTNNHPRINPKTIRALEEKAKIP-KADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
            +          R +  T   +EE  +   +AD  A YAK L ++L+TL  +V+GPNSVK
Sbjct: 309 GKATTSAMFGGGR-DVFTHEKIEELIQNQLRADPGAKYAKSLYLNLSTLAPFVAGPNSVK 367

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAA 377
           V+  ++DL  +DIK+NKAYLVSCTNSR SD+ +AA V        K   +APGV+FY+ A
Sbjct: 368 VATPLKDLEAKDIKVNKAYLVSCTNSRASDIAAAAKVFKEASKDGKPAVIAPGVKFYIGA 427

Query: 378 ASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMG 437
           AS+  +A A ++G W+ LL AG   LP+GCGPCIGLG GLLEPGEVGISA+NRNFKGRMG
Sbjct: 428 ASTLEQAAAEEAGDWKVLLDAGAQALPAGCGPCIGLGTGLLEPGEVGISASNRNFKGRMG 487

Query: 438 SKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEII--------------- 482
           S DA AYLAS  VVAASA+ GKI+ P       E P  GV+  II               
Sbjct: 488 STDAKAYLASQEVVAASALKGKIAGPGWY----EKP-EGVEKVIIGEGNGDAVHDKAVSI 542

Query: 483 -----------ENPVVEEEVN-------AQTEAPKQSVEILEGFPREFSGELVLCDADNI 524
                      E+ + + E N       A++   +   EIL GFP    GE+V CDADNI
Sbjct: 543 EEALAKLLGEAESMISDAEQNLGGSSQQAESAEEETLTEILPGFPERVEGEIVFCDADNI 602

Query: 525 NTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAAT 584
           NTDGIYPGKYTYQD+V  EKMA+VCMENYD EF      GD++V+GFNFG GSSREQAAT
Sbjct: 603 NTDGIYPGKYTYQDNVSTEKMAEVCMENYDKEFGKVAREGDVLVAGFNFGCGSSREQAAT 662

Query: 585 ALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAP-----KELTRRT 639
           A+LAK I LVV+GSFGNIFSRNSINNAL+ +E+P L+++LRE + G       K LTRRT
Sbjct: 663 AILAKRIPLVVAGSFGNIFSRNSINNALMGVEVPRLVERLRETFGGKEQGEENKALTRRT 722

Query: 640 GWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GW   WDV  +KV VTEGS  G     QKVGEL  N+QEII +GGLE WVKSQ+
Sbjct: 723 GWTFVWDVRRSKVTVTEGS--GGETWSQKVGELPPNVQEIIARGGLEKWVKSQI 774
>ref|XP_001822935.1| hypothetical protein [Aspergillus oryzae RIB40]
 sp|Q2U9G3|LYS4_ASPOR Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 dbj|BAE61802.1| unnamed protein product [Aspergillus oryzae]
          Length = 775

 Score =  799 bits (2064), Expect = 0.0,   Method: Composition-based stats.
 Identities = 432/733 (58%), Positives = 519/733 (70%), Gaps = 51/733 (6%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S     S  +SRA    Q LTEKIVQ Y+V L + K V SGDYV+I P  CM+HDNSWPV
Sbjct: 49  SAAVYSSLQASRA--VPQTLTEKIVQKYSVGLAKDKFVKSGDYVTISPHRCMTHDNSWPV 106

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GATK+ +P QIV TLDHD+QNKSEKNL KY+ IE+FAK   ++ YPAGRGIGH
Sbjct: 107 ALKFMSIGATKLHDPKQIVMTLDHDVQNKSEKNLQKYRQIEDFAKHQGVEFYPAGRGIGH 166

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           Q+M+EEGYA+P  + VASDSHSN YGG+G LGTPIVRTD A+IWATG+TWWQIPPVA+V 
Sbjct: 167 QVMVEEGYAWPGTLVVASDSHSNMYGGVGCLGTPIVRTDGASIWATGKTWWQIPPVAKVT 226

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
           L G LP GV+GKD+IVALCGLF+ D VLNHAIEFTG  +++ +L +D RLTIANMTTEWG
Sbjct: 227 LTGVLPPGVTGKDVIVALCGLFDKDDVLNHAIEFTGPEETMRSLSVDARLTIANMTTEWG 286

Query: 242 ALSGLFPVDKTLIDWYKNR--LQKLGTNNHP--RINPK--TIRALEEKAKIP-KADKDAH 294
           ALSGLFP+D  L  W K +     +G    P   + P+  T   LE+    P  ADK A 
Sbjct: 287 ALSGLFPIDNVLKGWLKGKATTAAMGLAEGPFKTLAPQHFTHPLLEQLFANPLTADKGAK 346

Query: 295 YAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADV 354
           YAK+L +DL+TL+ YVSGPNSVKV+  ++DL  Q+IK+NKAYLVSCTNSR SD+ +AA V
Sbjct: 347 YAKELFLDLSTLSPYVSGPNSVKVATPLKDLEAQNIKVNKAYLVSCTNSRASDIAAAARV 406

Query: 355 VCPTGDLN--KVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIG 412
                + N  KV K+A GVEFYVAAAS   +  A ++G W+ LL AG  PL  GC  CIG
Sbjct: 407 FKEAAEKNGGKVPKIADGVEFYVAAASIPEQLAAEEAGDWQALLDAGATPLLPGCAQCIG 466

Query: 413 LGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPA-------- 464
           LG GLLE GEVGISA+NRNFKGRMGS DA AYL SP VVAASA+ GK+S P         
Sbjct: 467 LGTGLLEAGEVGISASNRNFKGRMGSTDAKAYLGSPEVVAASALTGKLSGPGWYQAPEGL 526

Query: 465 --------------EVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEAPKQS--------V 502
                         + + T+E     +  + I+N V + E   +  AP++S         
Sbjct: 527 TEVVRGEGDGIREEDRMLTAEQALEKLIGQ-IDNLVADGE---KQFAPEESEESSGDSLT 582

Query: 503 EILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVH 562
           E+  GFP   SGE+V CDADNINTDGIYPGKYTYQDDV +E MAQVCM NYDA+F +   
Sbjct: 583 EVYPGFPERVSGEIVFCDADNINTDGIYPGKYTYQDDVSQETMAQVCMSNYDAQFSSIAK 642

Query: 563 PGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIK 622
            GDI+V+GFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P LI 
Sbjct: 643 EGDILVTGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLIN 702

Query: 623 KLREKY--QGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEII 680
           +LRE +  +G+ K LTRRTGW L WDV  +++ V EG  +GP    Q VGEL  N+QEII
Sbjct: 703 RLRESFSGEGSDKSLTRRTGWTLTWDVRRSRIEVQEGE-NGPKWTHQ-VGELPPNVQEII 760

Query: 681 VKGGLEGWVKSQL 693
            KGGLE WVK+++
Sbjct: 761 AKGGLEKWVKNEI 773
>ref|XP_001791786.1| hypothetical protein SNOG_01131 [Phaeosphaeria nodorum SN15]
 gb|EAT90780.2| hypothetical protein SNOG_01131 [Phaeosphaeria nodorum SN15]
          Length = 1654

 Score =  799 bits (2063), Expect = 0.0,   Method: Composition-based stats.
 Identities = 431/783 (55%), Positives = 522/783 (66%), Gaps = 103/783 (13%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           + +F  S H +      Q LTEKIVQ +AV + EGKV+ SGDYV+++P  CM+HDNSWPV
Sbjct: 52  AASFLPSLHETPK--TPQTLTEKIVQRHAVGVAEGKVLRSGDYVTLQPHRCMTHDNSWPV 109

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GAT+I +PSQIV TLDHD+QNK+EKNL KY  IE+FAKK  +  YPAGRGIGH
Sbjct: 110 ALKFMSIGATRISDPSQIVMTLDHDVQNKTEKNLKKYSQIEDFAKKQDVVFYPAGRGIGH 169

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEGYA+P  + VASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V 
Sbjct: 170 QIMVEEGYAWPGTLAVASDSHSNMYGGIGCLGTPVVRTDAASIWATGKTWWQIPPVAKVN 229

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
           L G +PQGV+GKD+IVAL GLFN D+VLNHAIEFTG  +++ ++P+D RLTIANMTTEWG
Sbjct: 230 LIGTMPQGVTGKDVIVALAGLFNKDEVLNHAIEFTGTDETIGSIPVDDRLTIANMTTEWG 289

Query: 242 ALSGLFPVDKTLIDWYKNR--LQKLGTNN----------HPRINP---KTIRALEEKAKI 286
           AL+GLFP+D  L  W + R  L  +G             H RI+     T    ++   I
Sbjct: 290 ALTGLFPIDSVLHGWLRARATLAAMGEGQAKDHHQQQFVHERIDKLFTATGMVGKQLGHI 349

Query: 287 PK----ADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTN 342
            K    ADK A YAK+L +DLATL+ YVSGPNSVKV+  + +L +Q+I INKAYLVSCTN
Sbjct: 350 FKPALAADKGAVYAKELFLDLATLSPYVSGPNSVKVATPLIELQEQNIPINKAYLVSCTN 409

Query: 343 SRLSDLQSAA----DVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKA 398
           SR SD+ +AA    D     GD  K+ K+A  V FY+AAAS   +  A ++G W+ LL+A
Sbjct: 410 SRASDIAAAARVFKDAAVANGD--KIPKIADHVSFYIAAASIPEQKTAEEAGDWQTLLEA 467

Query: 399 GCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLG 458
           G  PLP+GCGPCIGLG GLLEPGEVGISA+NRNFKGRMGS DA AYLASP VVAASA+ G
Sbjct: 468 GAQPLPAGCGPCIGLGTGLLEPGEVGISASNRNFKGRMGSPDAKAYLASPEVVAASALSG 527

Query: 459 KISSPAEVLSTSEIP--FSGVK----------------TEIIENPVVEEEVN----AQTE 496
            IS P       E P  + GV+                 +++E  + + E        TE
Sbjct: 528 SISGPGRY----EAPEGYEGVRRGEGDGILEENRMMTIEDMLEKAIKDAEAAIGSFGATE 583

Query: 497 APKQS--------------VEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPK 542
           +  QS               EIL GFP +  GE+V CDADNINTDGIYPGKYTYQDDV +
Sbjct: 584 SETQSAHPSAASGAEVETLTEILPGFPEKIHGEIVFCDADNINTDGIYPGKYTYQDDVTR 643

Query: 543 EKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNI 602
           EKMA+VCMENYD  F      GDI+VSGFNFG GSSREQAATA+LAKGI LVV+GSFGNI
Sbjct: 644 EKMAEVCMENYDVGFGQTAKAGDILVSGFNFGCGSSREQAATAILAKGIPLVVAGSFGNI 703

Query: 603 FSRNSINNALLTLEIPALIKKLREKYQGA------------------------------- 631
           FSRNSINNAL+ +E+P L  +LRE +  A                               
Sbjct: 704 FSRNSINNALMGVEVPRLTNRLREVFSSANTASSQQAIKEPSQNRESLDSPPPAATSQPA 763

Query: 632 -PKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVK 690
             K+LTRRTGW L+WD+  + V V EG          +VGEL  N+QEII  GGLE WVK
Sbjct: 764 ESKQLTRRTGWTLEWDIRRSTVTVQEGPNGDK--WNVRVGELPPNVQEIIALGGLENWVK 821

Query: 691 SQL 693
            ++
Sbjct: 822 KEI 824
>ref|XP_001396574.1| hypothetical protein An15g00350 [Aspergillus niger]
 sp|Q58FL6|LYS4_ASPNC Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|AAX53108.1| homoaconitate hydratase [Aspergillus niger]
 emb|CAK42204.1| unnamed protein product [Aspergillus niger]
          Length = 769

 Score =  795 bits (2054), Expect = 0.0,   Method: Composition-based stats.
 Identities = 422/736 (57%), Positives = 519/736 (70%), Gaps = 62/736 (8%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S     S  SSRA    Q LTEKIVQ YAV LP+GK V SGDYV+I P   M+HDNSWPV
Sbjct: 48  SAALFSSLQSSRA--VPQTLTEKIVQKYAVGLPDGKFVKSGDYVTIAPHRIMTHDNSWPV 105

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GA+K+ +P+Q+V TLDHD+QNK+EKNL KY+ IE FAK+H ++ YPAGRGIGH
Sbjct: 106 ALKFMSIGASKMHDPNQVVMTLDHDVQNKTEKNLQKYRQIEEFAKQHGVEFYPAGRGIGH 165

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEG+A+P  + VASDSHSNTYG + S+GTPIVRTDAA+IWATG+TWWQIPPVA+V 
Sbjct: 166 QIMVEEGFAWPGTLVVASDSHSNTYGAVASVGTPIVRTDAASIWATGKTWWQIPPVAKVT 225

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
             G LP GV+GKD+IVALCGLF+ D VLNHAIEFTG  +++ +LP+D RLTIANMTTEWG
Sbjct: 226 FTGILPPGVTGKDVIVALCGLFDKDDVLNHAIEFTGSEETMRSLPMDSRLTIANMTTEWG 285

Query: 242 ALSGLFPVDKTLIDWYKNR------------LQKLGTNN--HPRINPKTIRALEEKAKIP 287
           ALSGLFP+D  L  W K +             + L   N  HP I    +  L       
Sbjct: 286 ALSGLFPMDGVLKGWLKGKATTAAMGLADGPFKTLAARNFTHPAIEQLFVNPL------- 338

Query: 288 KADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSD 347
            ADK A YAK+L +DL+TL+ YVSGPNSVK++  +++L  QDIK++KAYLVSCTNSR SD
Sbjct: 339 TADKGAKYAKELFLDLSTLSPYVSGPNSVKIATPLKELEAQDIKVDKAYLVSCTNSRASD 398

Query: 348 LQSAADVVCPTGDLN--KVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPS 405
           + +AA V     + N  KV K+A GV+FY+AAAS   +  A  +G W+ LL+AG   LP+
Sbjct: 399 IAAAAKVFKDAAEKNGGKVPKIADGVKFYIAAASIPEQLAAEGAGDWQTLLEAGATALPA 458

Query: 406 GCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPA- 464
           GCGPCIGLG GLLEPGEVGISA+NRNFKGRMGS +A AYL SP +VAASA+ GK+S P  
Sbjct: 459 GCGPCIGLGTGLLEPGEVGISASNRNFKGRMGSTEAKAYLGSPEIVAASALSGKLSGPGW 518

Query: 465 --------EVLSTSEIPFSGVKTE--IIENPVVEEEVNAQTE----------APKQSV-- 502
                   EV+        G++ E  ++      E++  Q +          AP++ V  
Sbjct: 519 YQPPEGWTEVVRGEG---DGIREEDRMLNTEQALEKLLGQLDDLVADGEKRFAPEEKVEE 575

Query: 503 -----EILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEF 557
                E+  GFP   SGE+V CDADN+NTD IYPG +TYQD+VP EKMA+VCM NYD EF
Sbjct: 576 EGGLTEVYPGFPERVSGEIVFCDADNLNTDAIYPGYWTYQDNVPVEKMAEVCMSNYDKEF 635

Query: 558 RTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEI 617
            +    GDI+V G+NFG GSSREQAATALLAK I LVVSGSFGNIFSRNSINNAL+ LE+
Sbjct: 636 ASIAKEGDILVVGYNFGCGSSREQAATALLAKQIPLVVSGSFGNIFSRNSINNALMGLEV 695

Query: 618 PALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQ 677
           P L+ +LRE++    K+LTRRTGW L WDV  +++ + EG  +GP     KVGEL  N+Q
Sbjct: 696 PRLVSRLREEF--GDKQLTRRTGWTLTWDVRRSQIEIQEGQ-NGPK-WTHKVGELPPNVQ 751

Query: 678 EIIVKGGLEGWVKSQL 693
           EII KGGLE WVK+ +
Sbjct: 752 EIIAKGGLEKWVKNAI 767
>gb|EEH41326.1| homoaconitase [Paracoccidioides brasiliensis Pb01]
          Length = 809

 Score =  794 bits (2051), Expect = 0.0,   Method: Composition-based stats.
 Identities = 420/732 (57%), Positives = 513/732 (70%), Gaps = 68/732 (9%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q L EKIVQ ++V LP+GK V SGDYV+I P  CM+HDNSWPVALKFM +GA+K+++P Q
Sbjct: 84  QTLVEKIVQRFSVGLPQGKYVRSGDYVTISPYKCMTHDNSWPVALKFMSIGASKLQDPKQ 143

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QN+SEKNL KY+ IE FAK H +D YPAGRGIGHQIM+EEGYA+P  + VA
Sbjct: 144 VVMTLDHDVQNRSEKNLQKYRQIEQFAKTHEVDFYPAGRGIGHQIMVEEGYAWPGTLVVA 203

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V   G LP+GV+GKD+IVA
Sbjct: 204 SDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVTFTGVLPKGVTGKDVIVA 263

Query: 201 LCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLF+ D VLNHAIEF G   ++ +L ID RLTIANMTTEWGAL+GLFPVD  L  W +
Sbjct: 264 LCGLFDKDDVLNHAIEFAGSEATMRSLAIDDRLTIANMTTEWGALAGLFPVDSVLKGWLR 323

Query: 259 NR----------LQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           ++          +  L ++ + R     +  + E+     ADK A YAK+L +DL+TL  
Sbjct: 324 SKATTAAMWGSSVDGLPSSANTRFTHPLLDKMFEQPL--AADKGAQYAKELYLDLSTLPP 381

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN--KVNK 366
           YVSGPNSVKV++ + +L  QDIK+NKAYLVSCTNSR SDL +AA V       N  K+ K
Sbjct: 382 YVSGPNSVKVASPLNELEAQDIKVNKAYLVSCTNSRASDLAAAAKVFKEAAAKNNGKIPK 441

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           +A GV+FY+AAAS   +  A ++G W+ L++AG  PLP+GCGPCIGLG GLLEPGEVGIS
Sbjct: 442 LADGVKFYIAAASIPEQKAAEEAGDWQTLIEAGAEPLPAGCGPCIGLGTGLLEPGEVGIS 501

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFS----------G 476
           ATNRNFKGRMGS DA AYLASP VVAASA+ GKIS P       E P S          G
Sbjct: 502 ATNRNFKGRMGSTDAKAYLASPEVVAASALSGKISGPGWY----EKPESWTGVVRGEGDG 557

Query: 477 VKTE---IIENPVVEEEVN----------------------AQTEAPKQS---------- 501
           VK E   +     +E+ +N                      + T +P+QS          
Sbjct: 558 VKEEDRMLTAEEAIEKVINQLDNMVEDAEKIFGNESSSSSTSATASPQQSKNSSDNSSSL 617

Query: 502 VEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKV 561
            E+   FP   SGE++ CDADNINTDGIYPGKYTYQD+V + +MA VCM NYDA F T  
Sbjct: 618 TEVYPDFPSRVSGEIIFCDADNINTDGIYPGKYTYQDNVTRTQMAAVCMSNYDASFSTLA 677

Query: 562 HPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALI 621
            PGDI+V+GFNFG GSSREQAATA+LAK I LVV+GSFGNIFSRNSINNAL+ LE+P L+
Sbjct: 678 RPGDILVTGFNFGCGSSREQAATAILAKDIPLVVAGSFGNIFSRNSINNALMGLEVPRLV 737

Query: 622 KKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIV 681
            +LRE + G  K LT+RTGW L WDV  + + V EG  +G      +VGEL  N+QEII 
Sbjct: 738 SRLREVFGGQGK-LTQRTGWKLTWDVRRSLIEVQEG--EGGPKWTHRVGELPPNVQEIIA 794

Query: 682 KGGLEGWVKSQL 693
           +GGLE WVK+ +
Sbjct: 795 RGGLEKWVKNAI 806
>gb|EEH50136.1| homoaconitase [Paracoccidioides brasiliensis Pb18]
          Length = 857

 Score =  793 bits (2049), Expect = 0.0,   Method: Composition-based stats.
 Identities = 420/734 (57%), Positives = 508/734 (69%), Gaps = 70/734 (9%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q L EKIVQ YAV LP GK V SGDYV+I P  CM+HDNSWPVALKFM +GA+K+++P Q
Sbjct: 130 QTLVEKIVQRYAVGLPPGKYVRSGDYVTISPYKCMTHDNSWPVALKFMSIGASKLQDPKQ 189

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QNKSEKNL KY+ IE FAK H +D YPAGRGIGHQIM+EEGYA+P  + VA
Sbjct: 190 VVMTLDHDVQNKSEKNLHKYRQIEQFAKTHEVDFYPAGRGIGHQIMVEEGYAWPGTLVVA 249

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V   G LP+GV+GKD+IVA
Sbjct: 250 SDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVTFTGVLPRGVTGKDVIVA 309

Query: 201 LCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLF+ D VLNHAIEF G   +L +L I+ RLTIANMTTEWGAL+GLFPVD  L  W +
Sbjct: 310 LCGLFDKDDVLNHAIEFAGSEATLRSLAIEDRLTIANMTTEWGALAGLFPVDSVLKGWLR 369

Query: 259 NR----------LQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           ++          +  L ++ + R     +  + E+     ADK A YAK+L +DL+TL  
Sbjct: 370 SKATTAAMWGSSVDGLPSSANTRFTHPLLDKMFEQPM--AADKGAQYAKELYLDLSTLPP 427

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN--KVNK 366
           YVSGPNSVKV+  + +L  QDIK+NKAYLVSCTNSR SDL +AA V       N   + K
Sbjct: 428 YVSGPNSVKVARPLNELEAQDIKVNKAYLVSCTNSRASDLAAAAKVFKEAAAKNDGSIPK 487

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           +A GV+FY+AAAS   +  A ++G W+ L++AG  PLP+GCGPCIGLG GLLEPGEVGIS
Sbjct: 488 LADGVKFYIAAASIPEQKAAEEAGDWQTLIEAGAEPLPAGCGPCIGLGTGLLEPGEVGIS 547

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFS----------G 476
           ATNRNFKGRMGS DA AYLASP VVAASA+ GKIS P       E P S          G
Sbjct: 548 ATNRNFKGRMGSTDAKAYLASPEVVAASALSGKISGPGWY----EKPESWTGVVRGEGDG 603

Query: 477 VKTE---IIENPVVEEEVN------------------------AQTEAPKQS-------- 501
           +K E   +     +E+ +N                          +  P+QS        
Sbjct: 604 IKEEDRMLTAEEAIEKVINQLDNMVEDAEKIFGNASSSSSTSATASPQPQQSKDSSDNCA 663

Query: 502 --VEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRT 559
              E+  GFP   SGE++ CDADNINTDGIYPGKYTYQD+V + +MA VCM NYDA F T
Sbjct: 664 SLTEVYPGFPSRVSGEIIFCDADNINTDGIYPGKYTYQDNVSRTQMAAVCMSNYDASFST 723

Query: 560 KVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPA 619
              PGDI+ +GFNFG GSSREQAATA+LAK I LVV+GSFGNIFSRNSINNAL+ LE+P 
Sbjct: 724 LARPGDILATGFNFGCGSSREQAATAILAKDIPLVVAGSFGNIFSRNSINNALMGLEVPR 783

Query: 620 LIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEI 679
           L+ +LRE + G  K LT+RTGW L WDV  + + V EG  +G      +VGEL  N+QEI
Sbjct: 784 LVSRLREVFGGQGK-LTQRTGWKLTWDVRRSLIEVQEG--EGGPKWTHRVGELPPNVQEI 840

Query: 680 IVKGGLEGWVKSQL 693
           I +GGLE WVK+ +
Sbjct: 841 IARGGLEKWVKNAI 854
>gb|ABY84678.1| homoaconitase [Penicillium chrysogenum]
          Length = 785

 Score =  792 bits (2046), Expect = 0.0,   Method: Composition-based stats.
 Identities = 417/698 (59%), Positives = 499/698 (71%), Gaps = 28/698 (4%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ YAV LPEGK+V SGDY+S+ P +CM+HDNSWPVALKFM +GATKI  P Q
Sbjct: 87  QTLTEKIVQRYAVGLPEGKLVRSGDYISLAPGYCMTHDNSWPVALKFMSMGATKIHRPEQ 146

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QN S  NL KY+ IE FA +H ID YPAGRGIGHQ+M+EEGYA+P  M VA
Sbjct: 147 IVMTLDHDVQNTSAANLKKYEQIETFAGQHGIDFYPAGRGIGHQVMVEEGYAWPGTMAVA 206

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGT +VRTDAA+IWAT +TWWQIPPVA+V   G LP GV+GKD+IVA
Sbjct: 207 SDSHSNHYGGVGCLGTAVVRTDAASIWATSRTWWQIPPVARVTFTGTLPAGVTGKDVIVA 266

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDW-- 256
           LCGLFN+D VLNHAIEFTG  +++ +L +D RLTIANMTTEWGAL+GLFP+D+TL  W  
Sbjct: 267 LCGLFNSD-VLNHAIEFTGSEETMESLLVDSRLTIANMTTEWGALTGLFPIDRTLKRWLR 325

Query: 257 YKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSV 316
           YK     +  +   R      R  E  A    AD DA YAK+L ++L+TL+ YVSGPNSV
Sbjct: 326 YKATEAAMSEDRTTRQRITHERIDELFANPLTADPDAQYAKQLYLNLSTLSPYVSGPNSV 385

Query: 317 KVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN--KVNKVAPGVEFY 374
           KV+  + +L+QQ+IK+N+AY+VSCTNSR SDL +AA V       N     K+A GV+ Y
Sbjct: 386 KVATPLNELAQQNIKVNRAYIVSCTNSRASDLAAAAKVFKDAAKANPGTTPKIADGVKLY 445

Query: 375 VAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKG 434
           +AAAS+  +  A  +G W+ LL AG  PLP+GCGPCIGLG GLLEPGEVGISA+NRNFKG
Sbjct: 446 IAAASAPEQEAAESTGDWQALLDAGAQPLPAGCGPCIGLGTGLLEPGEVGISASNRNFKG 505

Query: 435 RMGSKDALAYLASPAVVAASAVLGKISSPA-----EVLSTSEIPFSGVKTEIIENPVVE- 488
           RMGS+DALAYLASP VVAASA+ G IS P      E  S  E  F        EN +   
Sbjct: 506 RMGSRDALAYLASPEVVAASALSGVISGPGAYQVPENWSGVEHGFGTGLPPTTENELTNL 565

Query: 489 --------EEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
                   + V +  E  K + EIL GFP   SGE+V  DADN++TD IYPGK TYQD+V
Sbjct: 566 LQQMESLIDRVESAGEDSKPATEILPGFPERISGEIVFLDADNLDTDNIYPGKLTYQDNV 625

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
            K+ MA  CM+NYD EF+    P DI+V+GFNFG GSSREQAATA+LAK I LVV+GSFG
Sbjct: 626 SKDDMAAACMQNYDPEFKGIAKPSDILVAGFNFGCGSSREQAATAILAKQIPLVVAGSFG 685

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAP-----KELTRRTGWFLKWDVADAKVVVT 655
           NIFSRNSINNAL+ LE+P LI++LR  +   P     ++LTRRTGW L WDV  + V V 
Sbjct: 686 NIFSRNSINNALMGLEVPRLIERLRASFAQPPPGDAGRQLTRRTGWTLTWDVKRSVVEVK 745

Query: 656 EGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           EG   G    EQ VGEL  N+QEII +GGLE WVK ++
Sbjct: 746 EGE-SGESWTEQ-VGELPANVQEIIAEGGLEAWVKGKV 781
>ref|XP_391125.1| hypothetical protein FG10949.1 [Gibberella zeae PH-1]
 sp|Q4HVQ9|LYS4_GIBZE Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
          Length = 776

 Score =  788 bits (2035), Expect = 0.0,   Method: Composition-based stats.
 Identities = 409/708 (57%), Positives = 504/708 (71%), Gaps = 42/708 (5%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q L EKI Q YAV L  GK + +GDY+++ P HCMSHDN+WP+A KF+ +GA+KI N  Q
Sbjct: 74  QTLVEKIAQQYAVGLAPGKKIKAGDYIALAPHHCMSHDNTWPIAKKFLDIGASKIHNNRQ 133

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QNKSE NL KY  I  FA+KH + HYPAGRGIGHQIM+EEGYA+P  ++VA
Sbjct: 134 VVFTLDHDVQNKSEANLKKYSLIHEFAEKHGVIHYPAGRGIGHQIMVEEGYAWPGTVSVA 193

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGT +VRTDAA+IWATGQTWWQ+PPVA+V   G LP GV+GKD+I+A
Sbjct: 194 SDSHSNMYGGIGCLGTAVVRTDAASIWATGQTWWQVPPVAKVTFTGILPPGVTGKDVIIA 253

Query: 201 LCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNR 260
           LCGLF +DQVLNHA+EF G    +LPID RLTI+NMTTEWGAL+G+FPVD+ LI WY+ +
Sbjct: 254 LCGLFRDDQVLNHAVEFAGGE--SLPIDDRLTISNMTTEWGALAGVFPVDEMLISWYRGK 311

Query: 261 LQK---LGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
                  G ++  RIN K +  LE+     +AD +A YAK+L ++L+TL+  V+GPNSVK
Sbjct: 312 ATTNAMFGGSSKDRINHKRVDELEQNRL--EADPNAKYAKELYLNLSTLSPIVAGPNSVK 369

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAA 377
           ++  +++L  +DI +NKAYLVSCTNSR SD+ +AA V       NK  K+APGV FY+AA
Sbjct: 370 IATPLKNLEAEDIPVNKAYLVSCTNSRASDIAAAARVFREAAKENKDVKIAPGVNFYIAA 429

Query: 378 ASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMG 437
           AS   +  A ++G W+ L  AG   LP+GCGPCIGLG GLLEPGEVGISA+NRNFKGRMG
Sbjct: 430 ASLPEQEIAEEAGDWQVLRDAGAQVLPAGCGPCIGLGTGLLEPGEVGISASNRNFKGRMG 489

Query: 438 SKDALAYLASPAVVAASAVLGKISSPA----------EVLSTSEIPFSGVKTEIIENPV- 486
           S  A AYLASP +VAASA+ GKI+ P            ++      +   K   IE+ + 
Sbjct: 490 STSAKAYLASPEIVAASALKGKIAGPGWYQKPEGVEKVIIGEGSGDYVADKALSIEDALD 549

Query: 487 --------------VEEEVNAQTEAPKQS------VEILEGFPREFSGELVLCDADNINT 526
                           E    Q  +P  +       EIL GFP +  GE+V CD+DNINT
Sbjct: 550 KLINEADALIAAAETSEGAKEQAASPTAAEGEESLTEILPGFPEKVEGEIVFCDSDNINT 609

Query: 527 DGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATAL 586
           DGIYPGKYTYQD+V  EKMA+VCMENYD EF      GDI+V+GFNFG GSSREQAATAL
Sbjct: 610 DGIYPGKYTYQDNVSVEKMAEVCMENYDTEFGKFAKAGDILVTGFNFGCGSSREQAATAL 669

Query: 587 LAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQG-APKELTRRTGWFLKW 645
           LAK I LVVSGSFGNIFSRNSINNAL+ +E+P L+++LRE Y+    K LTRRTGW L W
Sbjct: 670 LAKKIPLVVSGSFGNIFSRNSINNALMGVEVPRLVERLRETYKNDTEKPLTRRTGWKLVW 729

Query: 646 DVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           DV  +KV+VTE   DG    EQKVGEL  N+QEII +GGLE WVK+++
Sbjct: 730 DVRRSKVIVTEK--DGSS-WEQKVGELPANVQEIIARGGLEKWVKAKI 774
>ref|XP_001228555.1| hypothetical protein CHGG_10628 [Chaetomium globosum CBS 148.51]
 sp|Q2GN26|LYS4_CHAGB Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|EAQ84224.1| hypothetical protein CHGG_10628 [Chaetomium globosum CBS 148.51]
          Length = 797

 Score =  787 bits (2032), Expect = 0.0,   Method: Composition-based stats.
 Identities = 409/721 (56%), Positives = 504/721 (69%), Gaps = 54/721 (7%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ YA+ LP GK V +GDYV+I PA CM+HDNSWPV  KF  +GATKI N  Q
Sbjct: 80  QTLTEKIVQRYAIGLPPGKKVKAGDYVTISPAQCMTHDNSWPVVTKFTSIGATKIHNNRQ 139

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V TLDHD+QN SE NL KYKNIENFA++H +D YPAGRGIGHQIMIEEGYA+P  +TVA
Sbjct: 140 VVVTLDHDVQNTSESNLKKYKNIENFARQHGVDFYPAGRGIGHQIMIEEGYAWPGTLTVA 199

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+ +LGTP+VRTDAA+IWATGQTWWQIPP+A+V   G LP+GV+GKD+I+A
Sbjct: 200 SDSHSNMYGGVAALGTPVVRTDAASIWATGQTWWQIPPIAKVTFTGVLPRGVTGKDVIIA 259

Query: 201 LCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LC LFN D+VLNHAIEFTG   +L++LPID RLTI+NMTTEWGA++G+FP+D TL  W +
Sbjct: 260 LCALFNQDEVLNHAIEFTGSDLTLSSLPIDDRLTISNMTTEWGAVAGIFPIDSTLKSWLR 319

Query: 259 NRLQKLGTNN-----HPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGP 313
            +       N       RI    I  L      PK D  A YAK L ++L+TL+ +V+GP
Sbjct: 320 AKATVSAMLNPDLGGKARITHDKIEELFRDP--PKPDLGATYAKSLYLNLSTLSPFVAGP 377

Query: 314 NSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEF 373
           NSVKV+  V+DL  Q+IKINKAYLVSCTNSR SD+ +AA+V     +   + KVAPGVEF
Sbjct: 378 NSVKVATPVKDLEAQNIKINKAYLVSCTNSRASDIAAAANVFREAANGGPIPKVAPGVEF 437

Query: 374 YVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFK 433
           Y++AAS   +  A ++G W  LL AGCI  P+ C  CIGLG GLL+PG+VGISA+NRN+ 
Sbjct: 438 YISAASLPEQEIAEQAGDWRVLLDAGCIENPASCNACIGLGRGLLQPGDVGISASNRNWN 497

Query: 434 GRMGSKDALAYLASPAVVAASAVLGKISSPA----------------------------- 464
           GRMGS  A AYLASP VVAASA+ G+I+ P                              
Sbjct: 498 GRMGSPQAKAYLASPEVVAASALKGEIAGPGWYEKPEGVEKVIIGEGTGDLEADRAVSIA 557

Query: 465 ----EVLSTSEIPFSGVKTEIIENPVVEEEV--NAQTEAPKQS------VEILEGFPREF 512
                +++ +E   S  +  +  +P        NA  +A          ++IL GFP + 
Sbjct: 558 DALESLVAQAESMISSAEKSLESSPAAATGAVGNAMADATADQAGEEGLIDILPGFPEKV 617

Query: 513 SGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFN 572
           SGE+V CD+DNINTDGIYPGKYTYQDD+ ++ MAQV MENYD  F +   PGDI+V+GFN
Sbjct: 618 SGEIVFCDSDNINTDGIYPGKYTYQDDITRDTMAQVVMENYDRSFASLAKPGDILVAGFN 677

Query: 573 FGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAP 632
           FG GSSREQAATA+LAKGI LVV+GSFGNIFSRNSINNAL+ +E+P L+K+LRE++    
Sbjct: 678 FGCGSSREQAATAILAKGIPLVVAGSFGNIFSRNSINNALMGVEVPRLVKRLREEF--GE 735

Query: 633 KELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
           K  TRRTGW  +WDV  +KV VTEG  +G     QKVG+L  N+QEII  GGLE WVK +
Sbjct: 736 KVPTRRTGWRFEWDVRRSKVTVTEG--EGGETWSQKVGDLPPNVQEIIAVGGLEKWVKHR 793

Query: 693 L 693
           +
Sbjct: 794 I 794
>ref|XP_001547913.1| hypothetical protein BC1G_13341 [Botryotinia fuckeliana B05.10]
 gb|EDN19663.1| hypothetical protein BC1G_13341 [Botryotinia fuckeliana B05.10]
          Length = 806

 Score =  785 bits (2028), Expect = 0.0,   Method: Composition-based stats.
 Identities = 421/751 (56%), Positives = 508/751 (67%), Gaps = 89/751 (11%)

Query: 20  GQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPS 79
            Q LTEKIVQ Y++ L + KVV SGDYV++ P +CM+HDNSWPVA KFM +GATKI N +
Sbjct: 65  AQTLTEKIVQRYSLGLAKDKVVKSGDYVTLSPHYCMTHDNSWPVATKFMSIGATKIHNTN 124

Query: 80  QIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTV 139
           QIV TLDHD+QNKSE NL KYK IE FA++  +D YPAGRGIGHQIM+EEGYA+P  +TV
Sbjct: 125 QIVCTLDHDVQNKSETNLKKYKQIEEFARQQGVDFYPAGRGIGHQIMVEEGYAWPGTVTV 184

Query: 140 ASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIV 199
           ASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V L G LP GV+GKD+IV
Sbjct: 185 ASDSHSNMYGGIGCLGTPMVRTDAASIWATGRTWWQIPPIAKVTLTGVLPIGVTGKDVIV 244

Query: 200 ALCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWY 257
           ALCGLFN+D VLNHAIEFTG   ++ +LPID RLTIANMTTEWGALSGLFP+D  L  W 
Sbjct: 245 ALCGLFNSDDVLNHAIEFTGSEQTMRSLPIDDRLTIANMTTEWGALSGLFPIDSVLEKWL 304

Query: 258 KNRLQKLGTNNHPRINPKTIRALE-EKAKIPK-------ADKDAHYAKKLIIDLATLTHY 309
           + +            +PK  + L    A+I         ADK A YAK L ++L+TL+ Y
Sbjct: 305 RYK-----ATTSAMFDPKNGKELRFTHARIDDLVQNQLVADKGATYAKSLYLNLSTLSPY 359

Query: 310 VSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN---KVNK 366
           V+GPNSVK++  ++DL  Q IK+NKAYLVSCTNSR SDL +AA V     + +    + K
Sbjct: 360 VAGPNSVKIATPIRDLEAQKIKLNKAYLVSCTNSRASDLAAAAKVFKDAAESSPDKTIPK 419

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           +  GV FY+AAAS   +  A ++G W+ LL AG  PLPSGCGPCIGLG GLLEPGEVGIS
Sbjct: 420 IPEGVNFYIAAASIPEQEAAEEAGDWQALLAAGAQPLPSGCGPCIGLGTGLLEPGEVGIS 479

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPA---------------------- 464
           A+NRNFKGRMGS DA AYLASP VVAASA+ G IS P                       
Sbjct: 480 ASNRNFKGRMGSTDAKAYLASPEVVAASALSGYISGPGWYQPPIGVNKVVLGEGNGNVEE 539

Query: 465 -----------EVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFS 513
                      +++S +E    G ++ +       EE ++++       EIL GFP +  
Sbjct: 540 DKAISIEEALEKLISQAESIVDGAESSLFGTSSKPEETDSES-----LTEILPGFPEKVE 594

Query: 514 GELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNF 573
           GE+V CDADN+NTD IYPGKYTYQD V  EKMA+VCMENYD EFRT    GDI+VSGFNF
Sbjct: 595 GEIVFCDADNVNTDAIYPGKYTYQDGVSVEKMAEVCMENYDKEFRTIAREGDILVSGFNF 654

Query: 574 GTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKY----- 628
           G GSSREQAATA+LAK I +VV+GSFGNIFSRNSINNAL+ +E+P L+++LRE +     
Sbjct: 655 GCGSSREQAATAILAKKIPMVVAGSFGNIFSRNSINNALMGVEVPRLVQRLREHFAASAP 714

Query: 629 -----------------------QGAP---KELTRRTGWFLKWDVADAKVVVTEGSLDGP 662
                                  Q  P   K LTRRTGW   WDV  +KV V EG  +G 
Sbjct: 715 VPKKEVTEPSENSESLDSPKPAEQAVPQGEKILTRRTGWKFVWDVRRSKVEVQEG--EGG 772

Query: 663 VILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
               QKVGEL  N+QEII +GGLE WVK +L
Sbjct: 773 EKWSQKVGELPPNVQEIIARGGLEKWVKGEL 803
>gb|EDU46563.1| homoaconitase, mitochondrial precursor [Pyrenophora
           tritici-repentis Pt-1C-BFP]
          Length = 837

 Score =  785 bits (2027), Expect = 0.0,   Method: Composition-based stats.
 Identities = 431/762 (56%), Positives = 516/762 (67%), Gaps = 96/762 (12%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ +AV + +GK++ SGDYV+++P  CM+HDNSWPVALKFMG+GATKI +P Q
Sbjct: 78  QTLTEKIVQRHAVGVAQGKILRSGDYVTLQPHKCMTHDNSWPVALKFMGIGATKINDPKQ 137

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNK+EKNL KY  IE FAKK  +  YPAGRGIGHQIM+EEGYA+P  + VA
Sbjct: 138 IVMTLDHDVQNKTEKNLKKYSQIEEFAKKQDVVFYPAGRGIGHQIMVEEGYAWPGTLAVA 197

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V L G++PQGV+GKD+IVA
Sbjct: 198 SDSHSNMYGGIGCLGTPVVRTDAASIWATGKTWWQIPPVAKVTLNGKMPQGVTGKDVIVA 257

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           L GLFN D+VLNHAIEFTG  ++L ++P+D RLTIANMTTEWGAL+GLFP+D  L  W +
Sbjct: 258 LAGLFNKDEVLNHAIEFTGTDETLGSIPVDDRLTIANMTTEWGALTGLFPIDSVLHGWLR 317

Query: 259 NR--LQKLGTNN----------HPRINPKTIRAL----EEKAKIPK----ADKDAHYAKK 298
            R  L  +G             H RI+ K   A     E+   I K    ADK A YAK+
Sbjct: 318 ARATLAAMGEGQTKDHHQQQFVHERID-KLFTATGIVGEKLGHIFKPALAADKGAVYAKE 376

Query: 299 LIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPT 358
           L +DL+TL+ YVSGPNSVKV+  + +L  Q+I INKAYLVSCTNSR SD+ +AA+V    
Sbjct: 377 LFLDLSTLSPYVSGPNSVKVATPLLELQSQNIPINKAYLVSCTNSRASDIAAAANVFKDA 436

Query: 359 GDLN--KVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAG 416
             LN  K+ K+   V FY+AAAS   +  A ++G W+ LL+AG  PLPSGCGPCIGLG G
Sbjct: 437 AVLNGGKIPKIPDHVNFYIAAASIPEQKAAEEAGDWQILLEAGAQPLPSGCGPCIGLGTG 496

Query: 417 LLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIP--F 474
           LLEPGEVGISA+NRNFKGRMGS DA AYLASP VVAASA+ G IS P       E P  +
Sbjct: 497 LLEPGEVGISASNRNFKGRMGSPDAKAYLASPEVVAASALSGTISGPGWY----EAPEGY 552

Query: 475 SGVK----------------TEIIENPVVEEEVNAQT----EAPKQSV-----------E 503
            GV+                 +++E  + + E    T     +  QSV           E
Sbjct: 553 EGVRRGEGDGIPAEERMMTIEDMLEKAIKDAEAAIDTFGSDSSETQSVTPPTSDAETLTE 612

Query: 504 ILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHP 563
           IL GFP + SGE+V CDADNINTDGIYPGKYTYQDDV +EKMA+VCMENYD  F      
Sbjct: 613 ILPGFPEKISGEIVFCDADNINTDGIYPGKYTYQDDVTREKMAEVCMENYDPSFGQMAKA 672

Query: 564 GDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKK 623
           GDI+VSGFNFG GSSREQAATA+LAKGI LVV+GSFGNIFSRNSINNAL+ +E+P L  +
Sbjct: 673 GDILVSGFNFGCGSSREQAATAILAKGIPLVVAGSFGNIFSRNSINNALMGVEVPKLANR 732

Query: 624 LREKYQG--------------------------------APKELTRRTGWFLKWDVADAK 651
           LRE +                                    K+LTRRTGW L+WDV  + 
Sbjct: 733 LREAFSSKDASSSQQAIKEPSNNRESLDSPPPAAAAQPTQAKQLTRRTGWTLEWDVRRST 792

Query: 652 VVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           V V EG          KVGEL  N+QEII  GGLE WVK ++
Sbjct: 793 VSVQEGPNGSK--WNVKVGELPPNVQEIIALGGLENWVKKEI 832
>ref|XP_001598937.1| hypothetical protein SS1G_01026 [Sclerotinia sclerotiorum 1980]
 gb|EDN91623.1| hypothetical protein SS1G_01026 [Sclerotinia sclerotiorum 1980]
          Length = 806

 Score =  780 bits (2013), Expect = 0.0,   Method: Composition-based stats.
 Identities = 415/743 (55%), Positives = 506/743 (68%), Gaps = 73/743 (9%)

Query: 20  GQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPS 79
            Q LTEKIVQ Y++ L + K V SGDYV++ P +CM+HDNSWPVA KFM +GATKI N +
Sbjct: 65  AQTLTEKIVQRYSLGLAKDKFVKSGDYVTLSPHYCMTHDNSWPVATKFMSIGATKIHNTN 124

Query: 80  QIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTV 139
           QIV TLDHD+QNKSE NL KYK IE FA++  +D YPAGRGIGHQIM+EEGYA+P  +TV
Sbjct: 125 QIVCTLDHDVQNKSETNLKKYKQIEEFARQQGVDFYPAGRGIGHQIMVEEGYAWPGTVTV 184

Query: 140 ASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIV 199
           ASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V L G LP GV+GKD+IV
Sbjct: 185 ASDSHSNMYGGIGCLGTPMVRTDAASIWATGRTWWQIPPIAKVTLTGVLPIGVTGKDVIV 244

Query: 200 ALCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWY 257
           ALCGLFN+D VLNHAIEFTG   ++ +L +D RLTIANMTTEWGALSGLFP+D  L  W 
Sbjct: 245 ALCGLFNSDDVLNHAIEFTGSEQTMRSLSVDDRLTIANMTTEWGALSGLFPIDSVLESWL 304

Query: 258 KNRLQKLG-----TNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSG 312
           + +              PR     I  L +   +  ADK A YAK L ++L+TL+ YV+G
Sbjct: 305 RYKATTSAMFAPENGKEPRFTHARIDDLVQNQLV--ADKGATYAKSLYLNLSTLSPYVAG 362

Query: 313 PNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN---KVNKVAP 369
           PNSVK++  ++DL  Q IK+N+AYLVSCTNSR SDL +AA V     + +    + K+A 
Sbjct: 363 PNSVKIATPIRDLEAQKIKLNRAYLVSCTNSRASDLAAAAKVFKDAAESSPDKTIPKIAE 422

Query: 370 GVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATN 429
           GV FY+AAAS   +  A  +G W+ LL AG  PLPSGCGPCIGLG GLLEPGEVGISA+N
Sbjct: 423 GVNFYIAAASIPEQEAAEAAGDWQALLAAGAQPLPSGCGPCIGLGTGLLEPGEVGISASN 482

Query: 430 RNFKGRMGSKDALAYLASPAVVAASAVLGKISSPA---EVLSTSEIPFSGVKTEIIENPV 486
           RNFKGRMGS DA AYLASP +VAASA+ G ISSP    + +  +++        + E+  
Sbjct: 483 RNFKGRMGSTDAKAYLASPELVAASALSGYISSPGWYEQPVGVNKVVLGEGNGNVEEDKA 542

Query: 487 VE-----EEVNAQTEAPKQSVE--------------------ILEGFPREFSGELVLCDA 521
           +      E++ +Q E+     E                    IL GFP +  GE+V CDA
Sbjct: 543 ISIEEALEKLISQAESIVDGAESSLFGTSSKSDETETETLTEILPGFPEKVEGEIVFCDA 602

Query: 522 DNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQ 581
           DN+NTD IYPGKYTYQD V  EKMA+VCMENYD EFRT    GDI+VSGFNFG GSSREQ
Sbjct: 603 DNVNTDAIYPGKYTYQDGVSVEKMAEVCMENYDKEFRTIAREGDILVSGFNFGCGSSREQ 662

Query: 582 AATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKY------------- 628
           AATA+LAK I +VV+GSFGNIFSRNSINNAL+ +E+P L+++LRE +             
Sbjct: 663 AATAILAKKIPMVVAGSFGNIFSRNSINNALMGVEVPRLVQRLREHFAASAPVPKKEVTE 722

Query: 629 ---------------QGAP---KELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVG 670
                          Q  P   K LTRRTGW   WDV  +KV V EG  +G     QKVG
Sbjct: 723 PSENSESLDSPKPAEQAVPQGEKILTRRTGWKFVWDVRRSKVEVQEG--EGGEKWSQKVG 780

Query: 671 ELGKNLQEIIVKGGLEGWVKSQL 693
           EL  N+QEII +GGLE WVK+++
Sbjct: 781 ELPPNVQEIIARGGLEKWVKAEI 803
>ref|XP_001539249.1| homoaconitase, mitochondrial precursor [Ajellomyces capsulatus
           NAm1]
 gb|EDN09687.1| homoaconitase, mitochondrial precursor [Ajellomyces capsulatus
           NAm1]
          Length = 797

 Score =  780 bits (2013), Expect = 0.0,   Method: Composition-based stats.
 Identities = 413/734 (56%), Positives = 507/734 (69%), Gaps = 66/734 (8%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q L EKIVQ Y+V L  GK V SGDYV+I P  CM+HDNSWPVALKFM +GA+K+++  Q
Sbjct: 66  QTLVEKIVQKYSVGLAPGKKVRSGDYVTISPYKCMTHDNSWPVALKFMSIGASKLQDRKQ 125

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKSEKNL KY+ IE FAK H +D YPAGRGIGHQIM+EEGYA+P  + VA
Sbjct: 126 IVMTLDHDVQNKSEKNLLKYQQIEQFAKTHGVDFYPAGRGIGHQIMVEEGYAWPGTLVVA 185

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V   G LP+GV+GKD+IVA
Sbjct: 186 SDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVNFTGVLPKGVTGKDVIVA 245

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           LCGLF+ D VLNHAIEFTG  +++ +L ID RLTIANMTTEWGAL+G+FPVD  L  W +
Sbjct: 246 LCGLFDKDDVLNHAIEFTGSEETMRSLAIDDRLTIANMTTEWGALAGIFPVDNILKGWLR 305

Query: 259 NR----------LQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           ++          +  L ++ + R     +  + E+     ADK A Y+K+L +DL+TL  
Sbjct: 306 SKATAAAMWVSSVNGLPSSANTRFTHSQLDKVLERPL--AADKGAKYSKELSLDLSTLAP 363

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLN--KVNK 366
           YVSGPNSVKV+  +  L  QDIK+NKAYLVSCTNSR SDL +AA V     + N  K+ K
Sbjct: 364 YVSGPNSVKVATPLDKLEAQDIKVNKAYLVSCTNSRASDLAAAAKVFRQAAEKNDGKIPK 423

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           +A GV+FY+AAAS   +  A ++G W+ L++AG  PLP+GCGPCIGLG GLLEPGEVGIS
Sbjct: 424 LADGVKFYIAAASIPEQNAAEEAGDWQVLVEAGAQPLPAGCGPCIGLGTGLLEPGEVGIS 483

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPA---------------------- 464
           ATNRNFKGRMGS +A AYLASP VVAASA+ G IS P                       
Sbjct: 484 ATNRNFKGRMGSTEAKAYLASPEVVAASALRGTISGPGWYEKPEGWAGVSRGEGVGIKEE 543

Query: 465 EVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEA----------------------PKQSV 502
           + + T+E   + V  + ++N V + E     EA                           
Sbjct: 544 DRMLTAEEAIANVIGQ-LDNMVEDAEKIYGNEAISSTSTSQPSQQSKQQEEPGTDSSALT 602

Query: 503 EILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVH 562
           E+  GFP   SGE++ CDADNINTDGIYPGKYTYQD++  ++MAQVCM NYDA F     
Sbjct: 603 ELFPGFPECVSGEIIFCDADNINTDGIYPGKYTYQDNISTDQMAQVCMSNYDAAFSQLTR 662

Query: 563 PGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIK 622
            GDI+V+G+NFG GSSREQAATA+LAK I LVV+GSFGNIFSRNSINNAL+ LE+P LI+
Sbjct: 663 AGDILVTGYNFGCGSSREQAATAILAKRIPLVVAGSFGNIFSRNSINNALMGLEVPRLIQ 722

Query: 623 KLREKYQ---GAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEI 679
           +LRE +       K LTRRTGW L WDV  +++ V EG  +G      KVGEL  N+QEI
Sbjct: 723 RLRESFSSTGAGKKALTRRTGWTLTWDVRRSRIEVQEG--EGGEKWTHKVGELPPNVQEI 780

Query: 680 IVKGGLEGWVKSQL 693
           I +GGLE WVK+ +
Sbjct: 781 IARGGLEKWVKNAI 794
>ref|XP_753748.1| homoaconitase LysF [Aspergillus fumigatus Af293]
 sp|Q4WUL6|LYS4_ASPFU Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|EAL91710.1| homoaconitase LysF [Aspergillus fumigatus Af293]
          Length = 777

 Score =  766 bits (1978), Expect = 0.0,   Method: Composition-based stats.
 Identities = 402/705 (57%), Positives = 505/705 (71%), Gaps = 40/705 (5%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ+Y++ L EG+ V +GDYV + P  CM+HDNSWP ALKFM +GA+K+ NP Q
Sbjct: 78  QTLTEKIVQAYSLGLAEGQYVKAGDYVMLSPHRCMTHDNSWPTALKFMAIGASKVHNPDQ 137

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKSEKNL KY++IE FAK+H ID YPAG G+GHQIMIEEGYAFP  +TVA
Sbjct: 138 IVMTLDHDVQNKSEKNLKKYESIEKFAKQHGIDFYPAGHGVGHQIMIEEGYAFPGTVTVA 197

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA IWATG+TWW++PP+A+V+  G LP+GV+GKD+IVA
Sbjct: 198 SDSHSNMYGGVGCLGTPMVRTDAATIWATGRTWWKVPPIAKVQFTGTLPEGVTGKDVIVA 257

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           L GLFN D+VLN+AIEFTG  +++ +L +D RLTIANMTTEWGAL+GLFP+D TL  W +
Sbjct: 258 LSGLFNKDEVLNYAIEFTGSEETMKSLSVDTRLTIANMTTEWGALTGLFPIDSTLEQWLR 317

Query: 259 NRLQKLG-TNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
           ++      T    R   + I  L     +  AD+ A YAK L +DL+TL+ YVSGPNSVK
Sbjct: 318 HKAATASRTETARRFAEERINELFANPTV--ADRGARYAKYLYLDLSTLSPYVSGPNSVK 375

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAA----DVVCPTGDLNKVNKVAPGVEF 373
           V+  + +L +  +KI+KAYLVSCTNSR SD+ +AA    D V  TG      +VA GVEF
Sbjct: 376 VATPLDELEKHKLKIDKAYLVSCTNSRASDIAAAAKVFKDAVARTGG---PVRVADGVEF 432

Query: 374 YVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFK 433
           YVAAAS   +  A ++G W+ L+ AG IPLP+GC  CIGLGAGLL+ GEVGISA+NRNFK
Sbjct: 433 YVAAASKAEQKIAEEAGDWQALMDAGAIPLPAGCAVCIGLGAGLLKEGEVGISASNRNFK 492

Query: 434 GRMGSKDALAYLASPAVVAASAVLGKISSP----------AEVLSTSEIPFSGVKT---- 479
           GRMGS DA AYLASP VVAASA+ G IS P             +   E+  SG +     
Sbjct: 493 GRMGSPDAKAYLASPEVVAASALNGVISGPGIYKRPEDWTGVSIGEGEVVESGSRIDTTL 552

Query: 480 EIIENPV--VEEEVNAQTEA--PKQS-------VEILEGFPREFSGELVLCDADNINTDG 528
           E +E  +  ++  +++ ++A  P++S       V+I+ GFP +  GE++  DADNI+TDG
Sbjct: 553 EAMEKFIGQLDSMIDSSSKAVMPEESTGSGATEVDIVPGFPEKIEGEILFLDADNISTDG 612

Query: 529 IYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLA 588
           IYPGKYTYQDDV K+KMAQVCMENYD  F      GDI VSGFNFG GSSREQAAT++LA
Sbjct: 613 IYPGKYTYQDDVTKDKMAQVCMENYDPAFSGIARAGDIFVSGFNFGCGSSREQAATSILA 672

Query: 589 KGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVA 648
           K + LVV+GS GN FSRN++NNAL  LE+P LI++LRE + G+ K+ TRRTGW   W+V 
Sbjct: 673 KQLPLVVAGSIGNTFSRNAVNNALPLLEMPRLIERLREAF-GSEKQPTRRTGWTFTWNVR 731

Query: 649 DAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            ++V V EG   G     Q V     NLQ+II +GGLE WVK ++
Sbjct: 732 TSQVTVQEGP--GGETWSQSVPAFPPNLQDIIAQGGLEKWVKKEI 774
>gb|EDP51631.1| homoaconitase LysF [Aspergillus fumigatus A1163]
          Length = 777

 Score =  764 bits (1973), Expect = 0.0,   Method: Composition-based stats.
 Identities = 401/705 (56%), Positives = 504/705 (71%), Gaps = 40/705 (5%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ+Y++ L EG+ V +GDYV + P  CM+HDNSWP ALKFM +GA+K+ NP Q
Sbjct: 78  QTLTEKIVQAYSLGLAEGQYVKAGDYVMLSPHRCMTHDNSWPTALKFMAIGASKVHNPDQ 137

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKSEKNL KY++IE FA +H ID YPAG G+GHQIMIEEGYAFP  +TVA
Sbjct: 138 IVMTLDHDVQNKSEKNLKKYESIEKFANQHGIDFYPAGHGVGHQIMIEEGYAFPGTVTVA 197

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA IWATG+TWW++PP+A+V+  G LP+GV+GKD+IVA
Sbjct: 198 SDSHSNMYGGVGCLGTPMVRTDAATIWATGRTWWKVPPIAKVQFTGTLPEGVTGKDVIVA 257

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           L GLFN D+VLN+AIEFTG  +++ +L +D RLTIANMTTEWGAL+GLFP+D TL  W +
Sbjct: 258 LSGLFNKDEVLNYAIEFTGSEETMKSLSVDTRLTIANMTTEWGALTGLFPIDSTLEQWLR 317

Query: 259 NRLQKLG-TNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
           ++      T    R   + I  L     +  AD+ A YAK L +DL+TL+ YVSGPNSVK
Sbjct: 318 HKAATASRTETARRFAEERINELFANPTV--ADRGARYAKYLYLDLSTLSPYVSGPNSVK 375

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAA----DVVCPTGDLNKVNKVAPGVEF 373
           V+  + +L +  +KI+KAYLVSCTNSR SD+ +AA    D V  TG      +VA GVEF
Sbjct: 376 VATPLDELEKHKLKIDKAYLVSCTNSRASDIAAAAKVFKDAVARTGG---PVRVADGVEF 432

Query: 374 YVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFK 433
           YVAAAS   +  A ++G W+ L+ AG IPLP+GC  CIGLGAGLL+ GEVGISA+NRNFK
Sbjct: 433 YVAAASKAEQKIAEEAGDWQALMDAGAIPLPAGCAVCIGLGAGLLKEGEVGISASNRNFK 492

Query: 434 GRMGSKDALAYLASPAVVAASAVLGKISSP----------AEVLSTSEIPFSGVKT---- 479
           GRMGS DA AYLASP VVAASA+ G IS P             +   E+  SG +     
Sbjct: 493 GRMGSPDAKAYLASPEVVAASALNGVISGPGIYKRPEDWTGVSIGEGEVVESGSRIDTTL 552

Query: 480 EIIENPV--VEEEVNAQTEA--PKQS-------VEILEGFPREFSGELVLCDADNINTDG 528
           E +E  +  ++  +++ ++A  P++S       V+I+ GFP +  GE++  DADNI+TDG
Sbjct: 553 EAMEKFIGQLDSMIDSSSKAVMPEESTGSGATEVDIVPGFPEKIEGEILFLDADNISTDG 612

Query: 529 IYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLA 588
           IYPGKYTYQDDV K+KMAQVCMENYD  F      GDI VSGFNFG GSSREQAAT++LA
Sbjct: 613 IYPGKYTYQDDVTKDKMAQVCMENYDPAFSGIARAGDIFVSGFNFGCGSSREQAATSILA 672

Query: 589 KGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVA 648
           K + LVV+GS GN FSRN++NNAL  LE+P LI++LRE + G+ K+ TRRTGW   W+V 
Sbjct: 673 KQLPLVVAGSIGNTFSRNAVNNALPLLEMPRLIERLREAF-GSEKQPTRRTGWTFTWNVR 731

Query: 649 DAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            ++V V EG   G     Q V     NLQ+II +GGLE WVK ++
Sbjct: 732 TSQVTVQEGP--GGETWSQSVPAFPPNLQDIIAQGGLEKWVKKEI 774
>emb|CAC48042.1| homoaconitase [Aspergillus fumigatus]
          Length = 777

 Score =  764 bits (1973), Expect = 0.0,   Method: Composition-based stats.
 Identities = 401/705 (56%), Positives = 504/705 (71%), Gaps = 40/705 (5%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ+Y++ L EG+ V +GDYV + P  CM+HDNSWP ALKFM +GA+K+ NP Q
Sbjct: 78  QTLTEKIVQAYSLGLAEGQYVKAGDYVMLSPHRCMTHDNSWPTALKFMAIGASKVHNPDQ 137

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKSEKNL KY++IE FA +H ID YPAG G+GHQIMIEEGYAFP  +TVA
Sbjct: 138 IVMTLDHDVQNKSEKNLKKYESIEKFANQHGIDFYPAGHGVGHQIMIEEGYAFPGTVTVA 197

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA IWATG+TWW++PP+A+V+  G LP+GV+GKD+IVA
Sbjct: 198 SDSHSNMYGGVGCLGTPMVRTDAATIWATGRTWWKVPPIAKVQFTGTLPEGVTGKDVIVA 257

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           L GLFN D+VLN+AIEFTG  +++ +L +D RLTIANMTTEWGAL+GLFP+D TL  W +
Sbjct: 258 LSGLFNKDEVLNYAIEFTGSEETMKSLSVDTRLTIANMTTEWGALTGLFPIDSTLEQWLR 317

Query: 259 NRLQKLG-TNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
           ++      T    R   + I  L     +  AD+ A YAK L +DL+TL+ YVSGPNSVK
Sbjct: 318 HKAATASRTETARRFAEERINELFANPTV--ADRGARYAKYLYLDLSTLSPYVSGPNSVK 375

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAA----DVVCPTGDLNKVNKVAPGVEF 373
           V+  + +L +  +KI+KAYLVSCTNSR SD+ +AA    D V  TG      +VA GVEF
Sbjct: 376 VATPLDELEKHKLKIDKAYLVSCTNSRASDIAAAAKVFKDAVARTGG---PVRVADGVEF 432

Query: 374 YVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFK 433
           YVAAAS   +  A ++G W+ L+ AG IPLP+GC  CIGLGAGLL+ GEVGISA+NRNFK
Sbjct: 433 YVAAASKAEQKIAEEAGDWQALMDAGAIPLPAGCAVCIGLGAGLLKEGEVGISASNRNFK 492

Query: 434 GRMGSKDALAYLASPAVVAASAVLGKISSP----------AEVLSTSEIPFSGVKT---- 479
           GRMGS DA AYLASP VVAASA+ G IS P             +   E+  SG +     
Sbjct: 493 GRMGSPDAKAYLASPEVVAASALNGVISGPGIYKRPEDWTGVSIGEGEVVESGSRIDTTL 552

Query: 480 EIIENPV--VEEEVNAQTEA--PKQS-------VEILEGFPREFSGELVLCDADNINTDG 528
           E +E  +  ++  +++ ++A  P++S       V+I+ GFP +  GE++  DADNI+TDG
Sbjct: 553 EAMEKFIGQLDSMIDSSSKAVMPEESTGSGATEVDIVPGFPEKIEGEILFLDADNISTDG 612

Query: 529 IYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLA 588
           IYPGKYTYQDDV K+KMAQVCMENYD  F      GDI VSGFNFG GSSREQAAT++LA
Sbjct: 613 IYPGKYTYQDDVTKDKMAQVCMENYDPAFSGIARAGDIFVSGFNFGCGSSREQAATSILA 672

Query: 589 KGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVA 648
           K + LVV+GS GN FSRN++NNAL  LE+P LI++LRE + G+ K+ TRRTGW   W+V 
Sbjct: 673 KQLPLVVAGSIGNTFSRNAVNNALPLLEMPRLIERLREAF-GSEKQPTRRTGWTFTWNVR 731

Query: 649 DAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            ++V V EG   G     Q V     NLQ+II +GGLE WVK ++
Sbjct: 732 TSQVTVQEGP--GGETWSQSVPAFPPNLQDIIAQGGLEKWVKKEI 774
>ref|XP_001274165.1| homoaconitase LysF [Aspergillus clavatus NRRL 1]
 gb|EAW12739.1| homoaconitase LysF [Aspergillus clavatus NRRL 1]
          Length = 777

 Score =  763 bits (1971), Expect = 0.0,   Method: Composition-based stats.
 Identities = 407/713 (57%), Positives = 497/713 (69%), Gaps = 57/713 (7%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ+Y++ L +G+ V +GDYV + P  CM+HDNSWP ALKFM +GA+KI NP Q
Sbjct: 79  QTLTEKIVQAYSLGLKDGQYVKAGDYVMLSPHRCMTHDNSWPTALKFMAIGASKIHNPDQ 138

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKSEKNL KY+ IE FA KH +D YPAG G+GHQIMIEEGYAFP  +TVA
Sbjct: 139 IVMTLDHDVQNKSEKNLKKYEQIEQFADKHGVDFYPAGHGVGHQIMIEEGYAFPGTVTVA 198

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA IWATG+TWW++PP+A+V+  G LP+GV+GKD+IVA
Sbjct: 199 SDSHSNMYGGVGCLGTPMVRTDAATIWATGRTWWKVPPIAKVQFTGTLPEGVTGKDVIVA 258

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           L GLFN D+VLN+AIEFTG  +++ +L +D RLTIANMTTEWGAL+GLFP+D TL  W +
Sbjct: 259 LSGLFNKDEVLNYAIEFTGSEETMKSLSVDTRLTIANMTTEWGALTGLFPIDSTLEQWLR 318

Query: 259 NRLQKLGTNNHPRINPKTIRALEEK-----AKIPKADKDAHYAKKLIIDLATLTHYVSGP 313
           N+      +   R      R  EE+     A    AD+ A YAK L +DL+TL+ YVSGP
Sbjct: 319 NKATTASRSETAR------RFAEERINELFANPTVADRGAKYAKYLYLDLSTLSPYVSGP 372

Query: 314 NSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAA----DVVCPTGDLNKVNKVAP 369
           NSVKV+  V +L+QQ +K+NKAYLVSCTNSR SD+ +AA    D    TG      K+A 
Sbjct: 373 NSVKVATPVDELAQQKLKVNKAYLVSCTNSRASDIAAAAKVFKDAAARTGG---PVKIAE 429

Query: 370 GVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATN 429
           GVEFYVAAAS   +  A ++G W+ LL AG I LP+GC  CIGLGAGLL+ GE+GISA+N
Sbjct: 430 GVEFYVAAASKAEQKIAVQAGDWQALLDAGAIALPAGCAVCIGLGAGLLKDGEIGISASN 489

Query: 430 RNFKGRMGSKDALAYLASPAVVAASAVLGKISSPA------------------------- 464
           RNFKGRMGS DA AYLASP VVAASA+ G IS P                          
Sbjct: 490 RNFKGRMGSPDAKAYLASPEVVAASALNGIISGPGIYKRPEDWSGVSLGEGEVVESGNRI 549

Query: 465 -EVLSTSEIPFSGVKTEIIEN---PVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCD 520
              L T E  F G    +IE+    V+ EE  ++T      ++I+ GFP +  GE++  D
Sbjct: 550 DTTLETME-KFLGQLDSMIESSSKAVMPEESTSET----TEIDIVPGFPEKVEGEILFLD 604

Query: 521 ADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSRE 580
           ADNI+TDGIYPGKYTYQDDV KEKMAQVCMENYD  F      GDI VSGFNFG GSSRE
Sbjct: 605 ADNISTDGIYPGKYTYQDDVSKEKMAQVCMENYDPAFNNVARAGDIFVSGFNFGCGSSRE 664

Query: 581 QAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTG 640
           QAAT++LAK + LVV GS GN FSRN++NNAL  LE+P L+++LRE + G  K+ TRRTG
Sbjct: 665 QAATSILAKQLPLVVCGSIGNTFSRNAVNNALPLLEMPRLVERLREAF-GNDKQPTRRTG 723

Query: 641 WFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           W   W+V  ++V V EG   G     Q V  L  NLQ+II +GGLE WVK ++
Sbjct: 724 WSFTWNVRTSQVTVQEGP--GGETWTQSVPALPPNLQDIIAQGGLEKWVKKEI 774
>ref|XP_001259799.1| homoaconitase LysF [Neosartorya fischeri NRRL 181]
 gb|EAW17902.1| homoaconitase LysF [Neosartorya fischeri NRRL 181]
          Length = 777

 Score =  761 bits (1965), Expect = 0.0,   Method: Composition-based stats.
 Identities = 401/709 (56%), Positives = 497/709 (70%), Gaps = 48/709 (6%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEKIVQ+Y++ L EG+ V +GDYV + P  CM+HDNSWP ALKFM +GA+K+ NP+Q
Sbjct: 78  QTLTEKIVQAYSLGLAEGQYVKAGDYVMLSPHRCMTHDNSWPTALKFMAIGASKVHNPNQ 137

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           IV TLDHD+QNKSEKNL KY++IE FA +H ID YPAG G+GHQIMIEEGYAFP  +TVA
Sbjct: 138 IVMTLDHDVQNKSEKNLKKYESIEKFANQHGIDFYPAGHGVGHQIMIEEGYAFPGTVTVA 197

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGTP+VRTDAA IWATG+TWW++PP+A+V+  G LP+GV+GKD+IVA
Sbjct: 198 SDSHSNMYGGVGCLGTPMVRTDAATIWATGRTWWKVPPIAKVQFTGTLPEGVTGKDVIVA 257

Query: 201 LCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYK 258
           L GLFN D+VLN+AIEFTG  +++ +L +D RLTIANMTTEWGAL+GLFP+D TL  W +
Sbjct: 258 LSGLFNKDEVLNYAIEFTGSEETMKSLSVDTRLTIANMTTEWGALTGLFPIDLTLEQWLR 317

Query: 259 NRLQKLG-TNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
           ++      T    R   + I  L     +  AD+ A YAK L +DL+TL+ YVSGPNSVK
Sbjct: 318 HKAATASRTETARRFAEERINELFANPTV--ADRGAKYAKYLYLDLSTLSPYVSGPNSVK 375

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAA----DVVCPTGDLNKVNKVAPGVEF 373
           V+  + +L +  +KI+KAYLVSCTNSR SD+ +AA    D V  TG       VA GVEF
Sbjct: 376 VATPIDELEKHKLKIDKAYLVSCTNSRASDIAAAAKVFKDAVARTGG---PVTVADGVEF 432

Query: 374 YVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFK 433
           YVAAAS   +  A ++G W+ L+ AG IPLP+GC  CIGLGAGLL+ GEVGISA+NRNFK
Sbjct: 433 YVAAASKAEQKIAEEAGDWQALMDAGAIPLPAGCAVCIGLGAGLLKEGEVGISASNRNFK 492

Query: 434 GRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEE---- 489
           GRMGS DA AYLASP VVAASA+ G IS P       + P       I E  VVE     
Sbjct: 493 GRMGSPDAKAYLASPEVVAASALNGVISGPG----IYKRPEDWAGVSIGEGEVVESGTRI 548

Query: 490 ------------------EVNAQTEAPKQS-------VEILEGFPREFSGELVLCDADNI 524
                             E +++   P++S       V+I+ GFP +  GE++  DADNI
Sbjct: 549 DTTLEAMEKFIGQLDSMIESSSKAVMPEESTGSGATEVDIVPGFPEKIEGEILFLDADNI 608

Query: 525 NTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAAT 584
           +TDGIYPGKYTYQDDV K+KMAQVCMENYD  F      GDI VSGFNFG GSSREQAAT
Sbjct: 609 STDGIYPGKYTYQDDVTKDKMAQVCMENYDPAFSGIARAGDIFVSGFNFGCGSSREQAAT 668

Query: 585 ALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLK 644
           ++LAK + LVV+GS GN FSRN++NNAL  LE+P L+++LRE + G+ K+ TRRTGW   
Sbjct: 669 SILAKQLPLVVAGSIGNTFSRNAVNNALPLLEMPRLVERLREAF-GSEKQPTRRTGWTFT 727

Query: 645 WDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           W+V  ++V V EG   G     Q V     NLQ+II +GGLE WVK ++
Sbjct: 728 WNVRTSQVTVQEGP--GGETWSQSVPAFPPNLQDIIAQGGLEKWVKKEI 774
>ref|XP_001214855.1| homoaconitase, mitochondrial precursor [Aspergillus terreus
           NIH2624]
 gb|EAU33438.1| homoaconitase, mitochondrial precursor [Aspergillus terreus
           NIH2624]
          Length = 675

 Score =  754 bits (1946), Expect = 0.0,   Method: Composition-based stats.
 Identities = 401/678 (59%), Positives = 489/678 (72%), Gaps = 44/678 (6%)

Query: 55  MSHDNSWPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDH 114
           M+HDNSWPVALKFM +GATK+ NP QIV TLDHD+QNKSEKNL KY+ IE FAK H ++ 
Sbjct: 1   MTHDNSWPVALKFMSIGATKLHNPDQIVMTLDHDVQNKSEKNLQKYRQIEEFAKHHGVEF 60

Query: 115 YPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWW 174
           YPAGRGIGHQIM+EEG+A+P  + VASDSHSN YGG+G LGTP+VRTDAA++W+T QTWW
Sbjct: 61  YPAGRGIGHQIMVEEGFAWPGTLVVASDSHSNMYGGIGCLGTPVVRTDAASLWSTSQTWW 120

Query: 175 QIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLT 232
           QIPPVA++ L G LP GV+GKDIIVALCGLF+ D VLNHA+EFTG  +++ +L +D RLT
Sbjct: 121 QIPPVAKITLTGVLPAGVTGKDIIVALCGLFDKDNVLNHALEFTGSEETMWSLSVDDRLT 180

Query: 233 IANMTTEWGALSGLFPVDKTLIDWYKNR--LQKLGTNNHP--RINPK--TIRALEEKAKI 286
           IANMTTEWGALSGLFP+D TL  W + +     +G  + P   +  K  T  ALEE    
Sbjct: 181 IANMTTEWGALSGLFPIDNTLKGWLRGKATTAAMGLADGPFKSLAAKHFTHEALEELFAN 240

Query: 287 P-KADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRL 345
           P  ADK A YAK+  +DL+TL+ YV+GPNSVKV+  +++L  Q+IK++KAYL+SCTNSR 
Sbjct: 241 PLAADKGAKYAKEYFLDLSTLSPYVAGPNSVKVATPLKELEAQNIKVDKAYLLSCTNSRA 300

Query: 346 SDLQSAADVVCPTGDLN--KVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
           SD+ +AA V     + N  KV K+A GV+FY+AAAS   +A A  +G W+ L++AG  PL
Sbjct: 301 SDIAAAARVFREAAEKNGGKVPKIADGVKFYLAAASLPEQAAAEGAGDWQILMEAGATPL 360

Query: 404 PSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSP 463
           P+GCG CIGLG GLLEP EVGISA+NRNFKGRMGS +A AYL SP VVAASA+ GK+S P
Sbjct: 361 PAGCGTCIGLGEGLLEPNEVGISASNRNFKGRMGSVEAKAYLGSPEVVAASALNGKLSGP 420

Query: 464 A----------------------EVLSTSEIPFS---GVKTEII---ENPVVEEEVNAQT 495
                                  + + T+E       G   E++   E     EE +  T
Sbjct: 421 GWYQTPEGWNGVVYGEGDGIREEDRMLTAEQALEKVIGQLDELVMDGEKRFAPEESSPST 480

Query: 496 EAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA 555
           EA   + E+  GFP   SGE+V CDADN+NTDGIYPG YTYQD+V +EKMA+VCM NYD+
Sbjct: 481 EA---ATELYPGFPERVSGEIVFCDADNVNTDGIYPGAYTYQDNVSEEKMAEVCMSNYDS 537

Query: 556 EFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTL 615
           +F T    GDI+VSGFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ L
Sbjct: 538 KFSTIAKEGDILVSGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGL 597

Query: 616 EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKN 675
           E+P LI +LRE + G  K  TRRTGW L WDV  +++ V EG  +GP    QKVGEL  N
Sbjct: 598 EVPRLISRLRETFAGDAKVPTRRTGWTLTWDVRKSQIEVQEGE-NGPK-WTQKVGELPPN 655

Query: 676 LQEIIVKGGLEGWVKSQL 693
           +QEII KGGLE WVKS +
Sbjct: 656 VQEIIAKGGLEKWVKSAI 673
>emb|CAA89720.1| unknown [Saccharomyces cerevisiae]
          Length = 375

 Score =  729 bits (1881), Expect = 0.0,   Method: Composition-based stats.
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 319 SNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAA 378
           SNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAA
Sbjct: 1   SNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAA 60

Query: 379 SSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGS 438
           SSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGS
Sbjct: 61  SSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGS 120

Query: 439 KDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEAP 498
           KDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEAP
Sbjct: 121 KDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEAP 180

Query: 499 KQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFR 558
           KQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFR
Sbjct: 181 KQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFR 240

Query: 559 TKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIP 618
           TKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIP
Sbjct: 241 TKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIP 300

Query: 619 ALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQE 678
           ALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQE
Sbjct: 301 ALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQE 360

Query: 679 IIVKGGLEGWVKSQL 693
           IIVKGGLEGWVKSQL
Sbjct: 361 IIVKGGLEGWVKSQL 375
>ref|XP_001836222.1| hypothetical protein CC1G_06307 [Coprinopsis cinerea okayama7#130]
 gb|EAU85594.1| hypothetical protein CC1G_06307 [Coprinopsis cinerea okayama7#130]
          Length = 716

 Score =  712 bits (1837), Expect = 0.0,   Method: Composition-based stats.
 Identities = 391/725 (53%), Positives = 494/725 (68%), Gaps = 58/725 (8%)

Query: 8   TRSFHSSRAWLK-GQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALK 66
           TR F++S A  +  Q   EK+VQ YAV LPEGKVV +GDYV IKP H M+HDN+ PV  K
Sbjct: 3   TRRFYASVAAGRVPQTFIEKVVQKYAVGLPEGKVVKAGDYVMIKPEHVMTHDNTGPVISK 62

Query: 67  FMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIM 126
           F  +GATKI NPSQ V TLDHD+QN+S KNL KY NIE FA++H +D YPAGRGIGHQ++
Sbjct: 63  FKSIGATKIHNPSQPVFTLDHDVQNRSSKNLQKYANIEAFARQHGVDFYPAGRGIGHQVL 122

Query: 127 IEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKG 186
           +EEGYAFP  +TVASDSHSN YGG+G +GTPIVRTDAAA+WATG+TWWQ+P + +VELKG
Sbjct: 123 VEEGYAFPHTLTVASDSHSNMYGGVGCVGTPIVRTDAAALWATGKTWWQVPRMVKVELKG 182

Query: 187 QLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGL 246
           +L  GV+GKD+IVALCG FN D+VLN AIEFTG+ ++ L +D RLTIANMTTEWGAL+G+
Sbjct: 183 KLAPGVTGKDVIVALCGSFNKDEVLNAAIEFTGEGVSTLSVDERLTIANMTTEWGALAGV 242

Query: 247 FPVDKTLIDWYKNRLQKL--------------GTNNHPRINPKTIRALEEKAKIPKADKD 292
           FPVD+TL+ WY   L KL                  HPR+N + + AL +      +D  
Sbjct: 243 FPVDETLLSWYDRVLNKLELRTFASPSSSAIPPPPTHPRLNRERLSALRQTPL--SSDSG 300

Query: 293 AHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAA 352
           A Y+  L+ DL+TL  +VSGPNSVKVS  +  L  Q I INKAYLVSCTNSR+SD+ +AA
Sbjct: 301 AEYSSHLVFDLSTLVPHVSGPNSVKVSTPLPTLESQKIPINKAYLVSCTNSRVSDIAAAA 360

Query: 353 DVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIG 412
            VV       + +K+APGVEFY+AAASS ++ ++   G W+ L++AG   LP+GCGPCIG
Sbjct: 361 AVV-------RGHKIAPGVEFYIAAASSNVQQESEALGDWDALIQAGAKTLPAGCGPCIG 413

Query: 413 LGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEI 472
           LG GLLE GE+GISATNRN+KGRMGS +A AYLASPAVVAASA+ G IS PA  L  +++
Sbjct: 414 LGTGLLEDGEIGISATNRNYKGRMGSPNAQAYLASPAVVAASAINGFISGPAS-LDPAQL 472

Query: 473 PFSGVKTEII-ENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYP 531
           P +G  T  I E P       A    P     +LEGFP  FSG L+    DN+NTDGIYP
Sbjct: 473 PPAGAPTYTISEQPASAASSVAAENEP-----LLEGFPPAFSGPLLFAPQDNLNTDGIYP 527

Query: 532 GKYTYQDDVPKEKMAQVCMENYDAEFR---------------TKVHPGDIVVSGFNFGTG 576
           GKYTYQDD+  E+ A+V MENYD  F                + V PG ++V+G+NFGTG
Sbjct: 528 GKYTYQDDITLERQAEVVMENYDPGFASLVASLRKGFSTSEGSSVKPGVVLVAGYNFGTG 587

Query: 577 SSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQ------- 629
           SSREQAATAL + G+ LV++GSFG+IF RN+INN L+ LE P L+  L   Y        
Sbjct: 588 SSREQAATALKSAGVPLVIAGSFGDIFKRNAINNGLVCLESPELVADLTAAYTKDGKRGA 647

Query: 630 -GAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGW 688
            G   ELT   G  +  ++ +  V VT G ++       KV  +G ++QE+ + GGLEG+
Sbjct: 648 GGKDGELTVDKGLQVVVNMENGNVTVTTGGVEKVY----KVKPVGASVQELWLCGGLEGY 703

Query: 689 VKSQL 693
           +  ++
Sbjct: 704 ILKEI 708
>ref|XP_001880880.1| predicted protein [Laccaria bicolor S238N-H82]
 gb|EDR08655.1| predicted protein [Laccaria bicolor S238N-H82]
          Length = 733

 Score =  696 bits (1795), Expect = 0.0,   Method: Composition-based stats.
 Identities = 385/724 (53%), Positives = 490/724 (67%), Gaps = 64/724 (8%)

Query: 13  SSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGA 72
           S+R+    Q + EK+VQ YAV LPEGK V +GDYV I+P H M+HDN+ PV  KF  +GA
Sbjct: 25  STRSARVPQTVIEKVVQRYAVGLPEGKAVKAGDYVMIRPEHVMTHDNTGPVITKFNSIGA 84

Query: 73  TKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYA 132
           T I NPSQ V TLDHD+QNKS KNL+KY +IE FA+KH ID YPAGRGIGHQ+++EEGYA
Sbjct: 85  THIHNPSQPVFTLDHDVQNKSFKNLSKYASIEAFARKHSIDFYPAGRGIGHQVLVEEGYA 144

Query: 133 FPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGV 192
           FP  +TVASDSHSN YGG+G +GTPIVRTDAAA+WATG+TWWQ+P + +VEL+G+L  GV
Sbjct: 145 FPHTLTVASDSHSNMYGGVGCVGTPIVRTDAAALWATGKTWWQVPRMVKVELRGRLKPGV 204

Query: 193 SGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKT 252
           +GKD+IVALCG FN D+VLN A+EFTG+ +  L +D RLTIANMTTEWGAL G+FPVD+T
Sbjct: 205 TGKDVIVALCGSFNEDEVLNAALEFTGEGVAGLAVDDRLTIANMTTEWGALVGVFPVDET 264

Query: 253 LIDWYKNRLQKLGTNN--------------HPRINPKTIRALEEKAKIPKADKDAHYAKK 298
           L+ WY   L KL                  HPRIN + + AL  +     +D DA Y+  
Sbjct: 265 LLQWYDRVLAKLELRTFASPSSSAIPPPPVHPRINRQRLDAL--RTANLSSDLDAEYSSH 322

Query: 299 LIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPT 358
           L+ DL+TL  +VSGPNSVKVS  +  L    I I KAYLVSCTNSR+SD+ +AA V+   
Sbjct: 323 LVFDLSTLVPHVSGPNSVKVSTPLPLLEANKIAIQKAYLVSCTNSRVSDIAAAAAVM--- 379

Query: 359 GDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLL 418
               K  KVAPGV+FY+AAASS ++ ++   G W+ L++AG  PLP+GCGPCIGLG GLL
Sbjct: 380 ----KGQKVAPGVDFYIAAASSVVQQESETLGDWDALVQAGAKPLPAGCGPCIGLGTGLL 435

Query: 419 EPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLST--SEIP-FS 475
           E G+ GISATNRN+KGRMG   A AYLASPAVVAASA+ G IS PA + S+  ++ P FS
Sbjct: 436 EEGQTGISATNRNYKGRMGHPKAQAYLASPAVVAASAINGYISGPASLDSSPPAQTPTFS 495

Query: 476 GVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYT 535
                      + +   + +  P  +  +L+GFP  FSG L+    DN+NTDGIYPGKYT
Sbjct: 496 -----------ISQTSRSASTTPTDAEPLLDGFPAFFSGPLLFAPQDNLNTDGIYPGKYT 544

Query: 536 YQDDVPKEKMAQVCMENYDAEF-------RTKV---------HPGDIVVSGFNFGTGSSR 579
           YQDD+  E+ A+V MENYD  F       RTK+          PG ++V+G+NFGTGSSR
Sbjct: 545 YQDDITLERQAEVVMENYDPGFAVLVSSLRTKLPSPSPDAETKPGVVLVAGYNFGTGSSR 604

Query: 580 EQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQ--------GA 631
           EQAATAL A GI LV++GSFG+IF RN+INN L+ LE P L++ L E Y         G 
Sbjct: 605 EQAATALKAAGIPLVIAGSFGDIFKRNAINNGLVCLESPELVQDLTEAYAKDGRRGAGGK 664

Query: 632 PKELTRRTGWFLKWDVADAKVVV--TEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWV 689
             ELT   G  ++  + D +V V  +  S +G V     V  +G ++QE+ + GGLEG++
Sbjct: 665 QGELTVDKGLNVEVGMVDGRVYVRSSVSSAEGNVKTYH-VKPVGPSVQELWLCGGLEGYI 723

Query: 690 KSQL 693
             ++
Sbjct: 724 LKEI 727
>ref|XP_567622.1| homoaconitate hydratase [Cryptococcus neoformans var. neoformans
           JEC21]
 sp|Q5K9V9|LYS4_CRYNE Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|AAW46105.1| homoaconitate hydratase, putative [Cryptococcus neoformans var.
           neoformans JEC21]
          Length = 728

 Score =  678 bits (1749), Expect = 0.0,   Method: Composition-based stats.
 Identities = 385/713 (53%), Positives = 471/713 (66%), Gaps = 55/713 (7%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q L EKIVQ YAV L EG  V +GDYV IKP H M+HDN+ PV  KF+ L  +K+ NP Q
Sbjct: 31  QTLVEKIVQKYAVGLSEGVKVRAGDYVMIKPEHVMTHDNTGPVISKFLSLSCSKLDNPRQ 90

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
            V  LDHD+QN+SE N  KYK I+ FAK+H +D YPAGRGIGHQI++EEGYA+P  M VA
Sbjct: 91  PVFALDHDVQNQSETNQKKYKKIQAFAKEHGVDFYPAGRGIGHQIIVEEGYAWPGKMVVA 150

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGT IVRTDAA IWATG+ WWQIP +  V L G+L  GV+GKD+IVA
Sbjct: 151 SDSHSNHYGGVGCLGTAIVRTDAAGIWATGKFWWQIPRIVSVSLDGRLSPGVTGKDVIVA 210

Query: 201 LCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNR 260
           L GLFN D+VLN AIEFTG  +  L ID RLTIANMTTEWGA++G+FPVD  L +WY+  
Sbjct: 211 LAGLFNKDEVLNAAIEFTGSGVEHLSIDERLTIANMTTEWGAVAGVFPVDDKLKEWYQGI 270

Query: 261 LQK--------------LGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATL 306
           L+K              +G   HPR+N    R  +       AD  AHYA +L +DL+TL
Sbjct: 271 LRKAELRKFISPTVPSTVGAKVHPRLN--AARLDDAMTNRVVADPGAHYAARLSLDLSTL 328

Query: 307 THYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNK 366
             +VSGPNSVKV+  +  L    I INKAYLVSCTNSR SD+ SAA V+       +  K
Sbjct: 329 VPHVSGPNSVKVATALPKLLDPPIPINKAYLVSCTNSRASDIASAAQVL-------RGKK 381

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           VAPGVEFY+AAASS ++ DA  +G W+ L+ AG   LP+GCGPCIGLG GLLE GEVGIS
Sbjct: 382 VAPGVEFYIAAASSRVQEDAEAAGDWQTLIDAGAKTLPAGCGPCIGLGVGLLEKGEVGIS 441

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIP-FSGVKTEIIENP 485
           ATNRN+KGRMGS DA+AYLASPAVVAASA  G I  P E +  S++P +   K  IIE  
Sbjct: 442 ATNRNYKGRMGSPDAIAYLASPAVVAASAAKGVICGP-ESMDLSQLPQYEQPKFSIIEEG 500

Query: 486 VVEEEVNAQTEAPKQSVE-ILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEK 544
              EE     E  + S+E +LEGFP  F G L+    DN+ TDG+YPGKYTYQDD+  E+
Sbjct: 501 AAGEE--KPVEVDEASLEPLLEGFPAYFEGPLLFAPQDNLTTDGMYPGKYTYQDDITPER 558

Query: 545 MAQVCMENYDA-------EFRTKVH--------PGDIVVSGFNFGTGSSREQAATALLAK 589
            A+V MENYD        E RT +         PG I++SG+NFGTGSSREQAATA+   
Sbjct: 559 QAEVVMENYDPTFAATARELRTALPTASSPSTLPGAILLSGYNFGTGSSREQAATAIKNA 618

Query: 590 GINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQ--------GAPKELT-RRTG 640
           GI LV+ GSFG+IF RNSINN L+ +E P+LIK + E++         G   +LT    G
Sbjct: 619 GIPLVICGSFGDIFKRNSINNGLILIESPSLIKDMTERFAKDGVRNKGGKDGKLTVVPEG 678

Query: 641 WFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           W +K D     V V  G  +       KV   G+++QE+ V GGLEG++++ L
Sbjct: 679 WRIKVDSQRGLVTVNMGEEEEKTYPAAKV---GRSVQELWVNGGLEGFIRASL 728
>ref|XP_001729754.1| hypothetical protein MGL_3298 [Malassezia globosa CBS 7966]
 gb|EDP42540.1| hypothetical protein MGL_3298 [Malassezia globosa CBS 7966]
          Length = 717

 Score =  677 bits (1746), Expect = 0.0,   Method: Composition-based stats.
 Identities = 369/709 (52%), Positives = 473/709 (66%), Gaps = 59/709 (8%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q   EK+VQ YAV+      V SGDYVSI+PA  M+HDN+ PV  KF  +GA +I +P+Q
Sbjct: 32  QTYIEKVVQKYAVDWDPAVRVRSGDYVSIRPATVMTHDNTGPVITKFRSIGAKQIHDPTQ 91

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V  LDHD+QNKS KN+ KY  IE FA++  +D YPAGRGIGHQ+++EEGYAFP  + VA
Sbjct: 92  VVFALDHDVQNKSPKNMDKYARIEAFAREQGVDFYPAGRGIGHQVLVEEGYAFPQTLVVA 151

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G++GTPIVRTDAAAIWATG+TWWQ+PP+ +VEL GQL  GV+GKD+IVA
Sbjct: 152 SDSHSNMYGGVGAVGTPIVRTDAAAIWATGKTWWQLPPMVKVELTGQLRPGVTGKDVIVA 211

Query: 201 LCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNR 260
           LCG F ND+VLN AIEFTGD ++AL +D RL+I+NMTTEWGAL+G+FPVD T + WY   
Sbjct: 212 LCGYFKNDEVLNAAIEFTGDGVSALTVDERLSISNMTTEWGALAGVFPVDDTTLSWYDAL 271

Query: 261 LQKLG------------TNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           L+K+             ++ HPR+N   + AL EK +I  +D  A YAK L +DL+TL+ 
Sbjct: 272 LRKMDKLHFQMGSSPRPSDTHPRLNWSHLEAL-EKHRI-HSDDGASYAKHLRLDLSTLSP 329

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVA 368
           +VSGPNSVKV+  + +L +QDI I KAYLVSC NSR SD+++AADV+       +  KVA
Sbjct: 330 HVSGPNSVKVATPLYELEKQDIAIQKAYLVSCVNSRASDIKAAADVL-------RGRKVA 382

Query: 369 PGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISAT 428
           PGVEFY+A ASS ++ +A  +G W  LL AG  PLP+GCGPCIGLG GLL+ GEVGISAT
Sbjct: 383 PGVEFYLAPASSVVQREAENNGDWGSLLAAGARPLPAGCGPCIGLGMGLLKDGEVGISAT 442

Query: 429 NRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVE 488
           NRN+KGRMGS +ALAYLASPAVVAASA  GKI +P            G + E     V  
Sbjct: 443 NRNYKGRMGSPNALAYLASPAVVAASAAAGKICAP-----------EGTRPEDGRPLVSM 491

Query: 489 EEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQV 548
           E +++  +A     E+   FP +F+G LV    DN+NTD +YPGKYTYQDD+  E+ AQV
Sbjct: 492 ESIDSTPQAAAAPAELEPQFPPKFAGTLVFAPQDNLNTDALYPGKYTYQDDITPERQAQV 551

Query: 549 CMENYDAEFRTKV------------HPGDIVVSGFNFGTGSSREQAATALLAKGINLVVS 596
            MENYD  F + +                ++VSG+NFGTGSSREQAATAL   G+ +V++
Sbjct: 552 VMENYDPSFASSIAQERARRADNGEDAAVVLVSGYNFGTGSSREQAATALKYAGVPVVLA 611

Query: 597 GSFGNIFSRNSINNALLTLEIPALIKKLREKY--QGAPKELTRRTGWFLKWDVADAKVVV 654
           GSF ++F RN+INN L+ L+ P L+  L   Y   G      R+ G   +  V      V
Sbjct: 612 GSFSDVFKRNAINNGLICLQCPELVDDLTSSYAKDGQRGAGGRQPG---ELSVLLRDATV 668

Query: 655 TEGSLDGPVILEQKVGE----------LGKNLQEIIVKGGLEGWVKSQL 693
           +  S  G V L    G           +G+++QEI V GG+E WVK +L
Sbjct: 669 SLDSRTGAVELRFGNGSVKRYTTRPAGIGRSIQEIYVAGGMESWVKQRL 717
>ref|XP_772920.1| hypothetical protein CNBK2910 [Cryptococcus neoformans var.
           neoformans B-3501A]
 gb|EAL18273.1| hypothetical protein CNBK2910 [Cryptococcus neoformans var.
           neoformans B-3501A]
          Length = 728

 Score =  676 bits (1745), Expect = 0.0,   Method: Composition-based stats.
 Identities = 384/713 (53%), Positives = 471/713 (66%), Gaps = 55/713 (7%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q L EKIVQ YAV L EG  V +GDYV IKP H M+HDN+ PV  KF+ L  +K+ NP Q
Sbjct: 31  QTLVEKIVQKYAVGLSEGVKVRAGDYVMIKPEHVMTHDNTGPVISKFLSLSCSKLDNPRQ 90

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
            V  LDHD+QN+SE N  KYK I+ FAK+H +D YPAGRGIGHQI++EEGYA+P  M VA
Sbjct: 91  PVFALDHDVQNQSETNQKKYKKIQAFAKEHGVDFYPAGRGIGHQIIVEEGYAWPGKMVVA 150

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YGG+G LGT IVRTDAA IWATG+ WWQIP +  V L G+L  GV+GKD+IVA
Sbjct: 151 SDSHSNHYGGVGCLGTAIVRTDAAGIWATGKFWWQIPRIVSVSLDGRLSPGVTGKDVIVA 210

Query: 201 LCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNR 260
           L GLFN D+VLN AIEFTG  +  L ID RLTIANMTTEWGA++G+FPVD  L +WY+  
Sbjct: 211 LAGLFNKDEVLNAAIEFTGSGVEHLSIDERLTIANMTTEWGAVAGVFPVDDKLKEWYQGI 270

Query: 261 LQK--------------LGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATL 306
           L+K              +G   HPR+N    R  +       AD  AHYA +L +DL+TL
Sbjct: 271 LRKAELRKFISPTVPSTVGAKVHPRLN--AARLDDAMTNRVVADPGAHYAARLSLDLSTL 328

Query: 307 THYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNK 366
             +VSGPNSVKV+  +  L    I INKAYLVSCTNSR SD+ SAA V+       +  K
Sbjct: 329 VPHVSGPNSVKVATALPKLLDPPIPINKAYLVSCTNSRASDIASAAQVL-------RGKK 381

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           VAPGVEFY+AAASS ++ DA  +G W+ L+ AG   LP+GCGPCIGLG GLLE GEVGIS
Sbjct: 382 VAPGVEFYIAAASSRVQEDAEAAGDWQTLIDAGAKTLPAGCGPCIGLGVGLLEKGEVGIS 441

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIP-FSGVKTEIIENP 485
           ATNRN+KGRMGS DA+AYLASPAVVAASA  G I  P E +  S++P +   K  II+  
Sbjct: 442 ATNRNYKGRMGSPDAIAYLASPAVVAASAAKGVICGP-ESMDLSQLPQYEQPKFSIIKEG 500

Query: 486 VVEEEVNAQTEAPKQSVE-ILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEK 544
              EE     E  + S+E +LEGFP  F G L+    DN+ TDG+YPGKYTYQDD+  E+
Sbjct: 501 AAGEE--KPVEVDEASLEPLLEGFPAYFEGPLLFAPQDNLTTDGMYPGKYTYQDDITPER 558

Query: 545 MAQVCMENYDA-------EFRTKVH--------PGDIVVSGFNFGTGSSREQAATALLAK 589
            A+V MENYD        E RT +         PG I++SG+NFGTGSSREQAATA+   
Sbjct: 559 QAEVVMENYDPTFAATARELRTALPTASSPSTLPGAILLSGYNFGTGSSREQAATAIKNA 618

Query: 590 GINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQ--------GAPKELT-RRTG 640
           GI LV+ GSFG+IF RNSINN L+ +E P+LIK + E++         G   +LT    G
Sbjct: 619 GIPLVICGSFGDIFKRNSINNGLILIESPSLIKDMTERFAKDGVRNKGGKDGKLTVVPEG 678

Query: 641 WFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           W +K D     V V  G  +       KV   G+++QE+ V GGLEG++++ L
Sbjct: 679 WRIKVDSQRGLVTVNMGEEEEKTYPAAKV---GRSVQELWVNGGLEGFIRASL 728
>emb|CAA88513.1| unknown [Saccharomyces cerevisiae]
          Length = 324

 Score =  675 bits (1742), Expect = 0.0,   Method: Composition-based stats.
 Identities = 324/324 (100%), Positives = 324/324 (100%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG
Sbjct: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW
Sbjct: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI
Sbjct: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300

Query: 301 IDLATLTHYVSGPNSVKVSNTVQD 324
           IDLATLTHYVSGPNSVKVSNTVQD
Sbjct: 301 IDLATLTHYVSGPNSVKVSNTVQD 324
>ref|XP_760939.1| hypothetical protein UM04792.1 [Ustilago maydis 521]
 sp|Q4P521|LYS4_USTMA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|EAK86247.1| hypothetical protein UM04792.1 [Ustilago maydis 521]
          Length = 698

 Score =  663 bits (1711), Expect = 0.0,   Method: Composition-based stats.
 Identities = 377/700 (53%), Positives = 460/700 (65%), Gaps = 68/700 (9%)

Query: 22  NLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQI 81
           NL EKIVQ YAV+L  G  V SGDYVSI+P   M+HDN+ PV  KF  +GAT I NP Q+
Sbjct: 39  NLVEKIVQKYAVDLSPGSHVKSGDYVSIRPGTVMTHDNTGPVISKFGSIGATSIYNPDQV 98

Query: 82  VTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVAS 141
           V  LDHD+QNKS KNL KY  IE+FA+KH ID YPAGRGIGHQ+++EEGYAFP  + VAS
Sbjct: 99  VFALDHDVQNKSAKNLEKYSKIESFARKHGIDFYPAGRGIGHQVLVEEGYAFPQTLAVAS 158

Query: 142 DSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVAL 201
           DSHSN YGG+G LGTPIVRTDAAAIWATGQTWWQIP V +VELKG+LP+GV+GKD+IVAL
Sbjct: 159 DSHSNMYGGVGCLGTPIVRTDAAAIWATGQTWWQIPEVVKVELKGELPKGVTGKDVIVAL 218

Query: 202 CGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNRL 261
           CG FN DQVLN AIEF G  L++L ++ RL IANMTTEWGAL+GLFP D   + WY+ ++
Sbjct: 219 CGYFNKDQVLNAAIEFHGSGLSSLSVEERLAIANMTTEWGALAGLFPTDDVTLSWYEKQI 278

Query: 262 QK------------LGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHY 309
           +K              +N+HPR+N   +  L      P  D  A Y+K L +DLATL  +
Sbjct: 279 RKRDKLEFQIGSSPSPSNSHPRLNMNRLDELSRTLLRP--DSGAVYSKHLTLDLATLVPH 336

Query: 310 VSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAP 369
           VSGPNSVKVS  + +L+ Q+I INKAYLVSC NSR SDL++AADV+       +  KVAP
Sbjct: 337 VSGPNSVKVSTPLDELTSQNIAINKAYLVSCVNSRASDLKAAADVI-------RGKKVAP 389

Query: 370 GVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATN 429
           GVEFYVAAASS ++ +A ++G W  L+ AG  PLP+GCGPCIGLG GLLE GEVGISATN
Sbjct: 390 GVEFYVAAASSVVQREAEEAGDWGALMAAGAKPLPAGCGPCIGLGVGLLEDGEVGISATN 449

Query: 430 RNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEE 489
           RN+KGRMGS +A AYLASPAVVAASA+ GKI  P+++  +   P  G+K  I        
Sbjct: 450 RNYKGRMGSPNAQAYLASPAVVAASAIEGKICGPSDLDVSLLPPSKGLKYSISTAANAAP 509

Query: 490 EVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVC 549
              + T+A    VEIL+ FP  FSG L+    DN+NTDGIYPGKYTYQDD+  EK A+V 
Sbjct: 510 ADASSTDASAGGVEILDSFPTAFSGPLIFAPQDNLNTDGIYPGKYTYQDDITPEKQAEVV 569

Query: 550 MENYDAEFRTKV-------------HPGDIVVSGFNFGTGSSREQAATALLAKGINLVVS 596
           MENYDA F + V               G I++ G+NFGTGSSREQAATAL   GI LV++
Sbjct: 570 MENYDASFASTVAGLRASSSSSSSTKQGPILIGGYNFGTGSSREQAATALKYAGIPLVLA 629

Query: 597 GSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTE 656
           G       RNS   A+L  E    I                        D +   + ++ 
Sbjct: 630 GGV-----RNS--KAILLDESKVHI------------------------DSSTGSINLSF 658

Query: 657 GSLDGPVI---LEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
              DG  I      K   +G+++QEI   GGLE WVK ++
Sbjct: 659 KGPDGAKIERTYTAKPAGIGRSVQEIYTAGGLEKWVKQRI 698
>ref|YP_592040.1| homoaconitase [Acidobacteria bacterium Ellin345]
 gb|ABF41966.1| homoaconitase [Acidobacteria bacterium Ellin345]
          Length = 655

 Score =  608 bits (1569), Expect = e-172,   Method: Composition-based stats.
 Identities = 331/676 (48%), Positives = 434/676 (64%), Gaps = 36/676 (5%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q + EKI Q +    P+ K+  +GD++SI+P H M+HDN+  V  KF  +GATK+K+P Q
Sbjct: 3   QTVVEKIAQLHMSEGPKRKL-RAGDFLSIRPHHVMTHDNTSAVLKKFKAIGATKVKDPRQ 61

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
            V  LDHDIQN S+ N+ KYK IE FA +  ID Y AG GIGHQIM+E GY  P +  VA
Sbjct: 62  PVFALDHDIQNTSDDNIKKYKLIEKFAHEQGIDFYMAGTGIGHQIMVERGYVVPESFVVA 121

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSHSN YG +G++GTP+VRTDAAAIWATG+ WW IP   QV L+G+L  GV+GKD+I+ 
Sbjct: 122 SDSHSNMYGAMGAIGTPVVRTDAAAIWATGEFWWSIPRTIQVVLEGKLRPGVTGKDVIIT 181

Query: 201 LCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNR 260
           L GL+N D+VLN A+EF G  ++ L +D RL+IANM+TEWGAL+G FPVD+  I + +  
Sbjct: 182 LAGLYNKDEVLNAALEFAGSGVHTLTMDERLSIANMSTEWGALTGWFPVDQVTISYLR-- 239

Query: 261 LQKLGTNNHPRINPKTIRALEEKAKIPKA-DKDAHYAKKLIIDLATLTHYVSGPNSVKVS 319
            Q+ G          T   L + A+ P   DKDA YA K+ +DLA +T +VSGP+SV+V 
Sbjct: 240 -QRHGVARWQGTEKFTEEELLKWARAPLGPDKDATYAAKIELDLAQVTPHVSGPDSVQVM 298

Query: 320 NTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAAS 379
           ++V  + ++ I ++KAYL+SC NSR+SDL++AA V+          K+A  V+FYVA AS
Sbjct: 299 HSVAQMEEKKIAVHKAYLLSCVNSRVSDLEAAAKVLAG-------KKIAETVKFYVAPAS 351

Query: 380 SEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSK 439
             ++ +A K G W+ L+ AG I LP  CGPCIGLG GLLE GEVGISATNRNFKGRMGS+
Sbjct: 352 KHVQEEAEKRGIWKTLVDAGAITLPPSCGPCIGLGTGLLEAGEVGISATNRNFKGRMGSR 411

Query: 440 DALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEAPK 499
           DA  YLASP VVAASA+ G I+ P      +             N ++ E V A + A  
Sbjct: 412 DARCYLASPEVVAASALAGYITGPVHFEHAN------------PNIMLSEYVPAASAA-- 457

Query: 500 QSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRT 559
           ++V ILEGFP    G LV    DN+NTDGIY   YTY++D+  E MA+V MENYD EF  
Sbjct: 458 EAVSILEGFPASVKGRLVFVPQDNLNTDGIYGKDYTYREDMTPEMMAKVVMENYDPEFSA 517

Query: 560 KVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPA 619
           K   GD+VV G NFGTGSSREQA TAL AKGI LV++GSF   + RN+ NN  L +E P 
Sbjct: 518 KTSAGDVVVGGSNFGTGSSREQAVTALKAKGIPLVIAGSFSQTYLRNAFNNGFLCIETPE 577

Query: 620 LIKKLREKY--QGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQ 677
            + +L++K+  Q A K+ T   G  ++ D A + +     +   P         LG   Q
Sbjct: 578 FVAELKQKFAAQVANKKKTIVPGDEVEIDFATSTLKYAGETFTFPA--------LGSVPQ 629

Query: 678 EIIVKGGLEGWVKSQL 693
            ++  GG+E  V  +L
Sbjct: 630 SLVAAGGVENLVAQKL 645
>ref|XP_001745751.1| predicted protein [Monosiga brevicollis MX1]
 gb|EDQ89722.1| predicted protein [Monosiga brevicollis MX1]
          Length = 800

 Score =  568 bits (1464), Expect = e-160,   Method: Composition-based stats.
 Identities = 323/625 (51%), Positives = 401/625 (64%), Gaps = 34/625 (5%)

Query: 20  GQNLTEKIVQSYAV----NLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKI 75
           G  L EKIVQ + V    +  EG    SG  V I+P H M+HDN+  V  KF  L   ++
Sbjct: 39  GLTLVEKIVQRHLVRDDADDGEGAPARSGQIVKIRPRHVMTHDNTAAVMAKFEQLEVKQM 98

Query: 76  KNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPL 135
            +  Q V TLDH++Q++SEKNL KY+ IE FA  H +D Y AG GIGHQ M E GY  P 
Sbjct: 99  YSSEQPVFTLDHNVQDRSEKNLRKYQEIEAFAASHGVDFYKAGEGIGHQTMCERGYITPG 158

Query: 136 NMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGK 195
           +M VASDSHSN YGGLG LGTP+VRTDAA IWA G TWWQ+PPV QV+L GQL  GVSGK
Sbjct: 159 SMVVASDSHSNMYGGLGCLGTPVVRTDAAGIWALGHTWWQVPPVVQVKLTGQLQPGVSGK 218

Query: 196 DIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLID 255
           D+IVALCG FN D+VLN A+EFTGD +  L +D RLTIANMTTEWGAL+G+FP D+ L +
Sbjct: 219 DVIVALCGAFNQDEVLNAAVEFTGDGVATLSVDERLTIANMTTEWGALAGVFPWDEALRN 278

Query: 256 WYKNRL-----------QKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLA 304
           WY+ RL           Q+       RI+   I    +     +AD+DA YA +L +DL+
Sbjct: 279 WYEARLQSWQARANTLAQQAARQPASRISSSDIETWNQHPL--RADEDAVYAAELELDLS 336

Query: 305 TLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKV 364
           ++   V+GPNSVK   TV  L  Q IK++KAYLVSC N+R SDL +AADV+       + 
Sbjct: 337 SVEPCVAGPNSVKAMQTVSQLEAQHIKVHKAYLVSCVNARASDLAAAADVL-------RG 389

Query: 365 NKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVG 424
            K+AP VEFYVA AS E+   A+    W+ LL AGC PLP+GCGPCIGLG GLLE GEVG
Sbjct: 390 KKIAPHVEFYVAPASREVLETAQHQRVWDDLLAAGCTPLPAGCGPCIGLGTGLLEDGEVG 449

Query: 425 ISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIEN 484
           ISATNRNFKGRMGS++A AYLASPAVVAASA+ G I +P    +      + VK      
Sbjct: 450 ISATNRNFKGRMGSRNADAYLASPAVVAASALSGYICAPPGAPTAGSALVARVKH----- 504

Query: 485 PVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEK 544
                E  A  + P  +   + GFP   SG  V C  DNINTDGIY GKYTY++D+  E+
Sbjct: 505 ---SNEAIAPAQ-PTGTSRFVSGFPEHISGVPVFCLDDNINTDGIYAGKYTYREDISPEE 560

Query: 545 MAQVCMENYDAEFRTKVHP-GDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIF 603
            A+V MENYD +   ++     ++V+G NFGTGSSREQAATAL   G+  V+  S    +
Sbjct: 561 QARVVMENYDPQLAPRLAGVRSVLVAGANFGTGSSREQAATALKHAGVQAVICESVNETY 620

Query: 604 SRNSINNALLTLEIPALIKKLREKY 628
            RN++NN LL L  P  I+  +  +
Sbjct: 621 KRNALNNGLLVLVQPRFIQDAKAAF 645
>ref|XP_001224986.1| hypothetical protein CHGG_07330 [Chaetomium globosum CBS 148.51]
 gb|EAQ86077.1| hypothetical protein CHGG_07330 [Chaetomium globosum CBS 148.51]
          Length = 605

 Score =  300 bits (769), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 191/435 (43%), Positives = 248/435 (57%), Gaps = 69/435 (15%)

Query: 283 KAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTN 342
           K+ + K   DA YAK+L ++L+TL+ YVSGP++VKV+  + +L+ Q IK+++AY+VSCTN
Sbjct: 212 KSDVLKPHPDAVYAKQLYLNLSTLSPYVSGPDTVKVATPLHELAPQKIKVDRAYIVSCTN 271

Query: 343 SRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIP 402
           SR SD+++AA V     D N    V P +                   A   L++AG  P
Sbjct: 272 SRASDIRAAAKVFRDAADAN--GGVVPKI-------------------AGSILVEAGAQP 310

Query: 403 LPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISS 462
           L +GCGPCIGLG GLLEPGEV ISA+NRNFKGRMGS+DA AYL+SP  VAASA+ G I+ 
Sbjct: 311 LMAGCGPCIGLGTGLLEPGEVDISASNRNFKGRMGSRDAKAYLSSPEAVAASALSGIITG 370

Query: 463 PA-----------------EVLSTSEIPFSGVKTEI---IENPVVEEEVNAQTEAPKQSV 502
           P                   +  T+E   SG+  ++   I+   VE  V +  +    + 
Sbjct: 371 PGIYQVPKDWTGVDAGYGTGLPPTTETELSGLVQQLDSFIDR--VESAVTSAEDNNAAAT 428

Query: 503 EILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVH 562
           EIL GFP   SGE                     +  + K                    
Sbjct: 429 EILPGFPSRISGESSSATPTTSTRTPSTRASSPTKTTIAK-------------------- 468

Query: 563 PGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIK 622
           P DI+VSGFNFG GSSREQ+ATA+LA+ I LVV+ SFGN+FSRNSINNAL+ LEIP L++
Sbjct: 469 PHDIIVSGFNFGCGSSREQSATAILARDIPLVVAASFGNVFSRNSINNALMGLEIPRLVE 528

Query: 623 KLREKYQG-APKE---LTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQE 678
           +L  ++    P E   LTRRTGW L WDV  + V VTEG   G     +KVGEL  N+QE
Sbjct: 529 RLCARFPSTGPAEGRVLTRRTGWTLTWDVRRSLVEVTEGP--GGETWTEKVGELPANVQE 586

Query: 679 IIVKGGLEGWVKSQL 693
           II   GLE WVK++L
Sbjct: 587 IIAAEGLEAWVKAEL 601

 Score =  205 bits (521), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 101/193 (52%), Positives = 128/193 (66%), Gaps = 30/193 (15%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPSQ 80
           Q LTEK+VQ YAV LP GK+  SGDY+SI+PA  ++HDNS+PV  KFM +GATK+  PSQ
Sbjct: 57  QTLTEKVVQRYAVGLPPGKLFRSGDYISIEPATILTHDNSFPVMTKFMSIGATKVHRPSQ 116

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
           +V  LDHD+ NKSE                              +M+EEG+A+P  M VA
Sbjct: 117 LVMALDHDVSNKSE------------------------------VMVEEGHAWPGTMAVA 146

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSH   YGG+G LGTP+VRTDA +I AT +TW  +PP+A+V L G LPQGV+GKD+IVA
Sbjct: 147 SDSHGTHYGGVGCLGTPVVRTDACSICATDRTWCNVPPIARVRLTGTLPQGVTGKDVIVA 206

Query: 201 LCGLFNNDQVLNH 213
           LCG+F +D +  H
Sbjct: 207 LCGIFKSDVLKPH 219
Searching..................................................done Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|NP_010520.1|  Homoaconitase, catalyzes the conversion of...  1047   0.0  
gb|AAU09698.1|  YDR234W [Saccharomyces cerevisiae]               1045   0.0  
gb|EDN60567.1|  homoaconitase [Saccharomyces cerevisiae YJM789]  1044   0.0  
ref|XP_452878.1|  unnamed protein product [Kluyveromyces lac...   970   0.0  
ref|XP_448693.1|  unnamed protein product [Candida glabrata]...   927   0.0  
ref|XP_717326.1|  homoaconitase [Candida albicans SC5314] >g...   926   0.0  
ref|XP_460673.1|  hypothetical protein DEHA0F08019g [Debaryo...   925   0.0  
sp|Q2HZ33|LYS4_CANPA  Homoaconitase, mitochondrial precursor...   920   0.0  
ref|XP_001383888.2|  homoaconitase [Pichia stipitis CBS 6054...   915   0.0  
ref|XP_001646008.1|  hypothetical protein Kpol_1031p57 [Vand...   914   0.0  
ref|XP_503471.1|  hypothetical protein [Yarrowia lipolytica]...   912   0.0  
ref|XP_664125.1|  LYS4_EMENI Homoaconitase, mitochondrial pr...   911   0.0  
ref|XP_001485749.1|  hypothetical protein PGUG_01420 [Pichia...   907   0.0  
sp|Q92412|LYS4_EMENI  Homoaconitase, mitochondrial precursor...   906   0.0  
ref|XP_001523113.1|  homoaconitase, mitochondrial precursor ...   906   0.0  
ref|XP_359935.2|  hypothetical protein MGG_04842 [Magnaporth...   899   0.0  
ref|XP_001822935.1|  hypothetical protein [Aspergillus oryza...   897   0.0  
ref|XP_001396574.1|  hypothetical protein An15g00350 [Asperg...   897   0.0  
ref|XP_001911427.1|  unnamed protein product [Podospora anse...   896   0.0  
ref|XP_001248868.1|  hypothetical protein CIMG_02639 [Coccid...   894   0.0  
ref|XP_001539249.1|  homoaconitase, mitochondrial precursor ...   880   0.0  
gb|EEH41326.1|  homoaconitase [Paracoccidioides brasiliensis...   878   0.0  
gb|EEH50136.1|  homoaconitase [Paracoccidioides brasiliensis...   878   0.0  
ref|XP_958836.1|  homoaconitase, mitochondrial precursor [Ne...   876   0.0  
gb|ABY84678.1|  homoaconitase [Penicillium chrysogenum]           872   0.0  
ref|XP_001791786.1|  hypothetical protein SNOG_01131 [Phaeos...   870   0.0  
gb|EDU46563.1|  homoaconitase, mitochondrial precursor [Pyre...   867   0.0  
ref|XP_391125.1|  hypothetical protein FG10949.1 [Gibberella...   867   0.0  
ref|XP_001547913.1|  hypothetical protein BC1G_13341 [Botryo...   864   0.0  
ref|XP_001598937.1|  hypothetical protein SS1G_01026 [Sclero...   863   0.0  
ref|XP_001274165.1|  homoaconitase LysF [Aspergillus clavatu...   860   0.0  
ref|XP_753748.1|  homoaconitase LysF [Aspergillus fumigatus ...   860   0.0  
gb|EDP51631.1|  homoaconitase LysF [Aspergillus fumigatus A1...   858   0.0  
emb|CAC48042.1|  homoaconitase [Aspergillus fumigatus]            858   0.0  
ref|XP_001259799.1|  homoaconitase LysF [Neosartorya fischer...   854   0.0  
ref|XP_001228555.1|  hypothetical protein CHGG_10628 [Chaeto...   850   0.0  
ref|XP_001214855.1|  homoaconitase, mitochondrial precursor ...   835   0.0  
ref|NP_593437.1|  homoaconitate hydratase Lys2 [Schizosaccha...   830   0.0  
ref|NP_982841.1|  ABL106Cp [Ashbya gossypii ATCC 10895] >gi|...   826   0.0  
ref|XP_001836222.1|  hypothetical protein CC1G_06307 [Coprin...   776   0.0  
ref|XP_001880880.1|  predicted protein [Laccaria bicolor S23...   764   0.0  
ref|XP_567622.1|  homoaconitate hydratase [Cryptococcus neof...   764   0.0  
ref|XP_772920.1|  hypothetical protein CNBK2910 [Cryptococcu...   762   0.0  
ref|NP_622150.1|  aconitate hydratase [Thermoanaerobacter te...   754   0.0  
ref|YP_001665791.1|  putative aconitate hydratase [Thermoana...   752   0.0  
ref|YP_001039546.1|  aconitate hydratase [Clostridium thermo...   751   0.0  
ref|YP_002802745.1|  aconitase/isopropylmalate dehydratase f...   751   0.0  
ref|NP_214222.1|  aconitate hydratase [Aquifex aeolicus VF5]...   751   0.0  
ref|YP_001389789.1|  aconitase/isopropylmalate dehydratase f...   751   0.0  
ref|YP_001780072.1|  aconitase/isopropylmalate dehydratase f...   751   0.0  
ref|YP_001382802.1|  aconitase/isopropylmalate dehydratase f...   750   0.0  
ref|YP_001179560.1|  aconitate hydratase [Caldicellulosirupt...   748   0.0  
ref|XP_001729754.1|  hypothetical protein MGL_3298 [Malassez...   748   0.0  
ref|YP_001252962.1|  aconitate hydratase [Clostridium botuli...   748   0.0  
ref|ZP_02612428.1|  aconitase/isopropylmalate dehydratase fa...   747   0.0  
ref|YP_592040.1|  homoaconitase [Acidobacteria bacterium Ell...   747   0.0  
ref|YP_001785758.1|  aconitase/isopropylmalate dehydratase f...   746   0.0  
ref|ZP_02615951.1|  aconitase/isopropylmalate dehydratase fa...   746   0.0  
ref|NP_347607.1|  aconitate hydratase [Clostridium acetobuty...   744   0.0  
ref|ZP_02423106.1|  hypothetical protein EUBSIR_01964 [Eubac...   743   0.0  
ref|ZP_02081473.1|  hypothetical protein CLOLEP_02949 [Clost...   742   0.0  
ref|YP_001394364.1|  Aconitase-related protein [Clostridium ...   741   0.0  
ref|ZP_02177697.1|  aconitate hydratase [Hydrogenivirga sp. ...   737   0.0  
ref|YP_001919567.1|  putative aconitate hydratase [Clostridi...   736   0.0  
ref|YP_001307216.1|  aconitate hydratase [Clostridium beijer...   734   0.0  
ref|ZP_01576278.1|  putative aconitate hydratase [Clostridiu...   734   0.0  
gb|EAY57416.1|  Aconitase A [Leptospirillum sp. Group II UBA]     733   0.0  
ref|YP_001884383.1|  putative aconitate hydratase [Clostridi...   732   0.0  
emb|CAJ73630.1|  similar to aconitase 1 (aconitate hydratase...   732   0.0  
ref|XP_001241042.1|  hypothetical protein CIMG_08205 [Coccid...   731   0.0  
gb|EEH99428.1|  aconitate hydratase [Clostridium sp. 7_2_43FAA]   730   0.0  
ref|YP_430725.1|  aconitate hydratase [Moorella thermoacetic...   728   0.0  
ref|XP_566619.1|  3-isopropylmalate dehydratase [Cryptococcu...   727   0.0  
ref|ZP_02951252.1|  putative aconitate hydratase [Clostridiu...   725   0.0  
ref|YP_001678741.1|  aconitate hydratase, putative [Heliobac...   724   0.0  
ref|XP_957462.1|  3-isopropylmalate dehydratase [Neurospora ...   724   0.0  
ref|ZP_02742090.1|  aconitate hydratase [Clostridium diffici...   724   0.0  
ref|YP_001087310.1|  aconitate hydratase [Clostridium diffic...   724   0.0  
ref|XP_001821962.1|  hypothetical protein [Aspergillus oryza...   724   0.0  
ref|ZP_02726948.1|  aconitate hydratase [Clostridium diffici...   722   0.0  
ref|ZP_02868335.1|  hypothetical protein CLOSPI_02177 [Clost...   722   0.0  
ref|XP_389765.1|  hypothetical protein FG09589.1 [Gibberella...   722   0.0  
ref|XP_760939.1|  hypothetical protein UM04792.1 [Ustilago m...   722   0.0  
ref|ZP_02429558.1|  hypothetical protein CLORAM_02981 [Clost...   722   0.0  
sp|P55251|LEU2_RHIPU  3-isopropylmalate dehydratase (Isoprop...   721   0.0  
ref|XP_001909150.1|  unnamed protein product [Podospora anse...   721   0.0  
ref|XP_663490.1|  hypothetical protein AN5886.2 [Aspergillus...   721   0.0  
ref|ZP_02993983.1|  hypothetical protein CLOSPO_01101 [Clost...   720   0.0  
ref|ZP_02133049.1|  putative aconitate hydratase [Desulfatib...   719   0.0  
ref|XP_001208815.1|  3-isopropylmalate dehydratase [Aspergil...   716   0.0  
emb|CAD68161.1|  putative alpha-isopropylmalate isomerase [M...   715   0.0  
ref|XP_001644978.1|  hypothetical protein Kpol_1025p41 [Vand...   714   0.0  
ref|ZP_03929473.1|  possible aconitate hydratase [Anaerococc...   713   0.0  
emb|CAD68162.1|  putative alpha-isopropylmalate isomerase [M...   712   0.0  
dbj|BAD81058.1|  aconitase [Acidithiobacillus thiooxidans]        712   0.0  
ref|YP_878649.1|  aconitate hydratase [Clostridium novyi NT]...   712   0.0  
gb|EEH59812.1|  predicted protein [Micromonas pusilla CCMP1545]   712   0.0  
ref|XP_001803879.1|  hypothetical protein SNOG_13672 [Phaeos...   712   0.0  
ref|XP_755459.1|  3-isopropylmalate dehydratase [Aspergillus...   711   0.0  
gb|EDP54642.1|  3-isopropylmalate dehydratase, putative [Asp...   710   0.0  
ref|YP_344690.1|  aconitate hydratase [Nitrosococcus oceani ...   707   0.0  
gb|EEH47069.1|  3-isopropylmalate dehydratase [Paracoccidioi...   707   0.0  
ref|ZP_03916351.1|  possible aconitate hydratase [Anaerococc...   706   0.0  
ref|ZP_02078010.1|  hypothetical protein EUBDOL_01817 [Eubac...   706   0.0  
gb|EEJ79007.1|  aconitase [Anaerococcus prevotii DSM 20548]       706   0.0  
ref|XP_500383.1|  3-isopropylmalate dehydratase [Yarrowia li...   705   0.0  
ref|ZP_01291443.1|  Putative aconitate hydratase [delta prot...   705   0.0  
ref|YP_001319181.1|  aconitate hydratase [Alkaliphilus metal...   704   0.0  
emb|CAB99455.1|  3-isopropylmalate dehydratase [Yarrowia lip...   703   0.0  
ref|ZP_01287851.1|  Putative aconitate hydratase [delta prot...   703   0.0  
ref|XP_001399461.1|  hypothetical protein An02g03250 [Asperg...   703   0.0  
ref|ZP_02621054.1|  putative aconitate hydratase [Clostridiu...   702   0.0  
ref|YP_001230042.1|  aconitate hydratase [Geobacter uraniire...   702   0.0  
gb|ACO68967.1|  predicted protein [Micromonas sp. RCC299]         699   0.0  
ref|XP_001487770.1|  hypothetical protein PGUG_01147 [Pichia...   698   0.0  
sp|P18250|LEU2_PHYBL  3-isopropylmalate dehydratase (Isoprop...   697   0.0  
ref|ZP_01775867.1|  putative aconitate hydratase [Geobacter ...   697   0.0  
ref|NP_953491.1|  aconitate hydratase [Geobacter sulfurreduc...   697   0.0  
emb|CAA37257.1|  unnamed protein product [Phycomyces blakesl...   696   0.0  
gb|EDU44213.1|  3-isopropylmalate dehydratase [Pyrenophora t...   696   0.0  
ref|ZP_02862126.1|  hypothetical protein ANASTE_01339 [Anaer...   696   0.0  
ref|XP_762157.1|  3-isopropylmalate dehydratase [Ustilago ma...   695   0.0  
ref|XP_001224097.1|  conserved hypothetical protein [Chaetom...   695   0.0  
ref|XP_001260596.1|  3-isopropylmalate dehydratase, putative...   695   0.0  
ref|XP_363627.1|  conserved hypothetical protein [Magnaporth...   694   0.0  
ref|YP_385706.1|  aconitate hydratase [Geobacter metalliredu...   693   0.0  
ref|YP_387900.1|  aconitate hydratase [Desulfovibrio desulfu...   692   0.0  
ref|YP_357859.1|  aconitate hydratase [Pelobacter carbinolic...   692   0.0  
ref|YP_842722.1|  aconitate hydratase [Methanosaeta thermoph...   691   0.0  
ref|XP_001388036.1|  3-isopropylmalate dehydratase [Pichia s...   690   0.0  
ref|YP_325864.1|  aconitate hydratase [Natronomonas pharaoni...   689   0.0  
ref|ZP_03871645.1|  aconitase [Halorhabdus utahensis DSM 129...   687   0.0  
ref|YP_136708.1|  aconitate hydratase [Haloarcula marismortu...   686   0.0  
ref|XP_001415394.1|  predicted protein [Ostreococcus lucimar...   686   0.0  
ref|ZP_03999029.1|  aconitase [Halogeometricum borinquense D...   685   0.0  
ref|XP_718655.1|  alpha isopropylmalate isomerase [Candida a...   684   0.0  
ref|YP_445601.1|  aconitate hydratase [Salinibacter ruber DS...   684   0.0  
ref|ZP_02016130.1|  putative aconitate hydratase [Halorubrum...   681   0.0  
ref|XP_001527507.1|  3-isopropylmalate dehydratase [Lodderom...   681   0.0  
ref|NP_281140.1|  aconitate hydratase [Halobacterium sp. NRC...   675   0.0  
ref|ZP_01739293.1|  aconitate hydratase [Marinobacter sp. EL...   674   0.0  
ref|ZP_02062283.1|  putative aconitate hydratase [Rickettsie...   671   0.0  
ref|YP_658814.1|  aconitate hydratase [Haloquadratum walsbyi...   670   0.0  
ref|ZP_03904432.1|  aconitase [Desulfohalobium retbaense DSM...   669   0.0  
ref|XP_001745751.1|  predicted protein [Monosiga brevicollis...   667   0.0  
ref|ZP_03872275.1|  aconitase [Halomicrobium mukohataei DSM ...   665   0.0  
ref|ZP_01125510.1|  aconitate hydratase [Nitrococcus mobilis...   665   0.0  
ref|YP_702362.1|  aconitate hydratase [Rhodococcus sp. RHA1]...   659   0.0  
gb|EEH41733.1|  3-isopropylmalate dehydratase [Paracoccidioi...   656   0.0  
ref|YP_001772429.1|  aconitate hydratase [Methylobacterium s...   656   0.0  
ref|YP_002779303.1|  putative aconitase [Rhodococcus opacus ...   655   0.0  
ref|YP_001832046.1|  aconitate hydratase [Beijerinckia indic...   652   0.0  
ref|ZP_01061749.1|  aconitate hydratase [Flavobacterium sp. ...   651   0.0  
ref|NP_213641.1|  3-isopropylmalate dehydratase large subuni...   650   0.0  
ref|ZP_01737326.1|  aconitate hydratase [Marinobacter sp. EL...   647   0.0  
ref|ZP_00381223.1|  COG1048: Aconitase A [Brevibacterium lin...   646   0.0  
ref|YP_861642.1|  aconitate hydratase [Gramella forsetii KT0...   644   0.0  
ref|XP_445684.1|  unnamed protein product [Candida glabrata]...   643   0.0  
ref|XP_001393157.1|  hypothetical protein An08g10530 [Asperg...   642   0.0  
ref|ZP_03990030.1|  aconitate hydratase [Acidaminococcus sp....   641   0.0  
ref|XP_001268345.1|  mitochondrial aconitate hydratase, puta...   641   0.0  
ref|XP_001819597.1|  hypothetical protein [Aspergillus oryza...   641   0.0  
ref|XP_001834931.1|  hypothetical protein CC1G_10805 [Coprin...   640   0.0  
ref|YP_162278.1|  aconitate hydratase [Zymomonas mobilis sub...   639   0.0  
ref|YP_645548.1|  aconitate hydratase [Rubrobacter xylanophi...   639   0.0  
ref|YP_213145.1|  aconitate hydratase [Bacteroides fragilis ...   639   0.0  
ref|NP_013407.1|  Aconitase, required for the tricarboxylic ...   639   0.0  
ref|YP_101031.1|  aconitate hydratase [Bacteroides fragilis ...   639   0.0  
ref|XP_001537682.1|  3-isopropylmalate dehydratase [Ajellomy...   638   0.0  
ref|ZP_01961523.1|  hypothetical protein BACCAC_03155 [Bacte...   637   0.0  
ref|NP_578667.1|  3-isopropylmalate dehydratase large subuni...   637   0.0  
ref|XP_502616.1|  hypothetical protein [Yarrowia lipolytica]...   637   0.0  
ref|YP_001105950.1|  aconitate hydratase [Saccharopolyspora ...   637   e-180
ref|XP_001224733.1|  hypothetical protein CHGG_07077 [Chaeto...   637   e-180
ref|XP_001644039.1|  hypothetical protein Kpol_1026p29 [Vand...   637   e-180
ref|ZP_02070255.1|  hypothetical protein BACUNI_01674 [Bacte...   636   e-180
ref|YP_001299253.1|  aconitate hydratase [Bacteroides vulgat...   635   e-180
ref|ZP_02178221.1|  3-isopropylmalate dehydratase [Hydrogeni...   635   e-180
ref|XP_001587807.1|  hypothetical protein SS1G_11047 [Sclero...   635   e-180
gb|AAM10631.1|AF434843_1  aconitase protein [Bacteroides fra...   634   e-179
ref|XP_641958.1|  aconitate hydratase [Dictyostelium discoid...   633   e-179
emb|CAB72317.1|  aconitase [Daphnia pulex]                        632   e-179
ref|NP_810985.1|  aconitate hydratase [Bacteroides thetaiota...   632   e-179
ref|XP_001912055.1|  unnamed protein product [Podospora anse...   631   e-179
gb|AAA34389.1|  aconitase (ACO1) (EC 4.2.1.3)                     629   e-178
ref|XP_961070.1|  hypothetical protein NCU04280 [Neurospora ...   629   e-178
ref|ZP_01924229.1|  putative aconitate hydratase [Victivalli...   629   e-178
ref|XP_452974.1|  unnamed protein product [Kluyveromyces lac...   628   e-178
ref|ZP_02436892.1|  hypothetical protein BACSTE_03162 [Bacte...   627   e-178
ref|YP_001568607.1|  3-isopropylmalate dehydratase, large su...   627   e-178
ref|NP_984065.1|  ADL032Wp [Ashbya gossypii ATCC 10895] >gi|...   627   e-177
ref|NP_127025.1|  3-isopropylmalate dehydratase large subuni...   627   e-177
gb|AAT92542.1|  mitochondrial aconitate hydratase [Yarrowia ...   626   e-177
ref|ZP_02060515.1|  homoaconitate hydratase family protein [...   623   e-176
emb|CAQ43555.1|  Probable aconitate hydratase 2 [Zygosacchar...   623   e-176
ref|XP_390374.1|  hypothetical protein FG10198.1 [Gibberella...   621   e-176
ref|YP_001211082.1|  3-isopropylmalate dehydratase large sub...   621   e-176
ref|NP_594031.1|  aconitate hydratase [Schizosaccharomyces p...   621   e-176
ref|NP_012335.1|  Putative mitochondrial aconitase isozyme; ...   620   e-175
ref|XP_460250.1|  hypothetical protein DEHA0E23078g [Debaryo...   619   e-175
ref|ZP_01804711.1|  hypothetical protein CdifQ_04000915 [Clo...   617   e-174
ref|NP_596189.1|  aconitate hydratase [Schizosaccharomyces p...   617   e-174
ref|YP_001716546.1|  3-isopropylmalate dehydratase, large su...   615   e-174
ref|XP_362853.1|  hypothetical protein MGG_08584 [Magnaporth...   614   e-174
ref|YP_517602.1|  hypothetical protein DSY1369 [Desulfitobac...   613   e-173
sp|Q24XT4|LEU2_DESHY  3-isopropylmalate dehydratase large su...   613   e-173
ref|NP_969574.1|  aconitate hydratase [Bdellovibrio bacterio...   612   e-173
ref|XP_001728868.1|  hypothetical protein MGL_4035 [Malassez...   612   e-173
ref|YP_431084.1|  3-isopropylmalate dehydratase large subuni...   611   e-173
ref|YP_001680099.1|  3-isopropylmalate dehydratase, large su...   611   e-173
ref|YP_001180124.1|  3-isopropylmalate dehydratase large sub...   610   e-173
emb|CAJ73691.1|  similar to 3-isopropylmalate dehydratase, l...   610   e-173
ref|XP_001646409.1|  hypothetical protein Kpol_2001p56 [Vand...   610   e-172
Sequences not found previously or not previously below threshold:

ref|NP_927033.1|  aconitate hydratase [Gloeobacter violaceus...   733   0.0  
ref|ZP_02060705.1|  putative aconitate hydratase [Hydrogenob...   729   0.0  
sp|P55811|LEU2_RHINI  3-isopropylmalate dehydratase (Isoprop...   704   0.0  
ref|ZP_01388850.1|  Putative aconitate hydratase [Geobacter ...   697   0.0  
ref|XP_001275417.1|  3-isopropylmalate dehydratase, putative...   696   0.0  
ref|NP_594576.1|  3-isopropylmalate dehydratase Leu2 (predic...   693   0.0  
ref|YP_967373.1|  aconitate hydratase [Desulfovibrio vulgari...   692   0.0  
ref|YP_010285.1|  aconitate hydratase [Desulfovibrio vulgari...   691   0.0  
ref|XP_001837333.1|  hypothetical protein CC1G_00469 [Coprin...   691   0.0  
ref|YP_846224.1|  aconitate hydratase [Syntrophobacter fumar...   682   0.0  
ref|XP_458182.1|  hypothetical protein DEHA0C12595g [Debaryo...   674   0.0  
ref|ZP_01594594.1|  putative aconitate hydratase [Geobacter ...   674   0.0  
ref|XP_444788.1|  hypothetical protein CAGL0A00363g [Candida...   673   0.0  
sp|Q00464|LEU2_CANMA  3-isopropylmalate dehydratase (Isoprop...   672   0.0  
gb|EDN61592.1|  isopropylmalate isomerase [Saccharomyces cer...   670   0.0  
ref|YP_461949.1|  aconitate hydratase [Syntrophus aciditroph...   669   0.0  
ref|NP_011506.1|  Isopropylmalate isomerase, catalyzes the s...   667   0.0  
ref|NP_986835.1|  AGR169Wp [Ashbya gossypii ATCC 10895] >gi|...   667   0.0  
ref|XP_451218.1|  unnamed protein product [Kluyveromyces lac...   666   0.0  
ref|XP_001877213.1|  predicted protein [Laccaria bicolor S23...   666   0.0  
gb|AAB19612.1|  isopropylmalate isomerase [Saccharomyces cer...   665   0.0  
ref|YP_885507.1|  aconitate hydratase [Mycobacterium smegmat...   663   0.0  
ref|ZP_02117691.1|  Aconitate hydratase [Methylobacterium no...   647   0.0  
gb|EEH48819.1|  3-isopropylmalate dehydratase large subunit ...   644   0.0  
ref|XP_751171.1|  mitochondrial aconitate hydratase [Aspergi...   642   0.0  
ref|ZP_01121842.1|  aconitate hydratase [Robiginitalea bifor...   642   0.0  
gb|EDP55486.1|  mitochondrial aconitate hydratase, putative ...   642   0.0  
ref|XP_001258433.1|  mitochondrial aconitate hydratase, puta...   640   0.0  
ref|ZP_03886142.1|  aconitase [Gordonia bronchialis DSM 4324...   638   0.0  
gb|AAC61778.1|  aconitase [Aspergillus terreus]                   637   0.0  
ref|XP_001247958.1|  aconitate hydratase, mitochondrial prec...   636   e-180
gb|ABH10644.1|  aconitase [Coccidioides posadasii]                636   e-180
ref|ZP_02066314.1|  hypothetical protein BACOVA_03310 [Bacte...   633   e-179
emb|CAD60751.1|  unnamed protein product [Podospora anserina...   633   e-179
ref|XP_001878558.1|  aconitate hydratase [Laccaria bicolor S...   633   e-179
ref|XP_663129.1|  hypothetical protein AN5525.2 [Aspergillus...   632   e-179
ref|ZP_03900244.1|  aconitase [Dyadobacter fermentans DSM 18...   630   e-179
ref|XP_570245.1|  aconitase [Cryptococcus neoformans var. ne...   630   e-178
ref|ZP_00949139.1|  aconitate hydratase [Croceibacter atlant...   628   e-178
ref|XP_001689702.1|  aconitate hydratase [Chlamydomonas rein...   628   e-178
sp|P49609|ACON_GRAVE  Aconitate hydratase, mitochondrial pre...   628   e-178
ref|XP_001219634.1|  hypothetical protein CHGG_00413 [Chaeto...   627   e-177
ref|YP_678828.1|  aconitate hydratase [Cytophaga hutchinsoni...   627   e-177
ref|ZP_01254620.1|  aconitate hydratase [Psychroflexus torqu...   626   e-177
gb|AAH26196.1|  Aconitase 2, mitochondrial [Homo sapiens]         625   e-177
emb|CAG38805.1|  ACO2 [Homo sapiens]                              625   e-177
ref|YP_003633.1|  aconitate hydratase [Leptospira interrogan...   625   e-177
ref|NP_714871.1|  aconitate hydratase [Leptospira interrogan...   625   e-177
ref|XP_001486725.1|  conserved hypothetical protein [Pichia ...   625   e-177
gb|ABZ96059.1|  Aconitate hydratase [Leptospira biflexa sero...   624   e-177
ref|XP_360978.1|  conserved hypothetical protein [Magnaporth...   623   e-176
ref|XP_716225.1|  mitochondrial aconitate hydratase [Candida...   623   e-176
ref|YP_799496.1|  aconitate hydratase [Leptospira borgpeters...   622   e-176
ref|YP_001302462.1|  aconitate hydratase [Parabacteroides di...   622   e-176
ref|ZP_03966826.1|  aconitate hydratase [Sphingobacterium sp...   620   e-176
ref|XP_712172.1|  mitochondrial aconitase [Candida albicans ...   620   e-176
ref|ZP_01061488.1|  aconitate hydratase [Flavobacterium sp. ...   620   e-175
ref|YP_862527.1|  aconitate hydratase [Gramella forsetii KT0...   620   e-175
ref|XP_452349.1|  unnamed protein product [Kluyveromyces lac...   620   e-175
ref|XP_759046.1|  hypothetical protein UM02899.1 [Ustilago m...   619   e-175
ref|XP_001525239.1|  aconitate hydratase, mitochondrial prec...   619   e-175
ref|XP_388129.1|  hypothetical protein FG07953.1 [Gibberella...   619   e-175
ref|XP_959787.1|  hypothetical protein NCU02366 [Neurospora ...   618   e-175
emb|CAA76360.1|  aconitate hydratase [Piromyces sp. E2]           618   e-175
gb|EDN63190.1|  aconitase [Saccharomyces cerevisiae YJM789]       617   e-175
ref|ZP_01252893.1|  aconitate hydratase [Psychroflexus torqu...   617   e-174
ref|XP_001485951.1|  hypothetical protein PGUG_01622 [Pichia...   617   e-174
ref|ZP_01107815.1|  aconitate hydratase [Flavobacteriales ba...   617   e-174
ref|XP_001386080.1|  Aconitase, mitochondrial [Pichia stipit...   616   e-174
ref|XP_001879583.1|  aconitate hydratase 2 [Laccaria bicolor...   616   e-174
gb|EEH33999.1|  3-isopropylmalate dehydratase large subunit ...   615   e-174
ref|XP_459431.1|  hypothetical protein DEHA0E02948g [Debaryo...   614   e-174
ref|XP_001607990.1|  PREDICTED: similar to aconitase, mitoch...   613   e-173
ref|ZP_01885744.1|  aconitate hydratase [Pedobacter sp. BAL3...   613   e-173
sp|P17279|LEU2_RHIRA  3-isopropylmalate dehydratase (Isoprop...   613   e-173
ref|XP_001525166.1|  aconitate hydratase, mitochondrial prec...   613   e-173
ref|ZP_03850820.1|  aconitate hydratase [Chryseobacterium gl...   612   e-173
ref|YP_001296062.1|  aconitate hydratase [Flavobacterium psy...   612   e-173
ref|ZP_02032556.1|  hypothetical protein PARMER_02572 [Parab...   612   e-173
ref|XP_750430.1|  aconitate hydratase, mitochondrial [Asperg...   612   e-173
ref|XP_391994.1|  PREDICTED: similar to Aconitase CG9244-PB ...   611   e-173
ref|XP_001385589.2|  aconitate hydratase [Pichia stipitis CB...   611   e-173
ref|ZP_01720574.1|  aconitate hydratase [Algoriphagus sp. PR...   611   e-173
ref|XP_503960.1|  hypothetical protein [Yarrowia lipolytica]...   611   e-173
ref|XP_446075.1|  unnamed protein product [Candida glabrata]...   610   e-172
gb|AAH68910.1|  LOC398139 protein [Xenopus laevis]                610   e-172
ref|XP_001264984.1|  aconitate hydratase, mitochondrial [Neo...   610   e-172
>ref|NP_010520.1| Homoaconitase, catalyzes the conversion of homocitrate to
           homoisocitrate, which is a step in the lysine
           biosynthesis pathway; Lys4p [Saccharomyces cerevisiae]
 sp|P49367|LYS4_YEAST Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAA63764.1| homoaconitase [Saccharomyces cerevisiae]
 gb|AAA88902.1| lysine biosynthesis enzyme homoaconitase [Saccharomyces cerevisiae]
          Length = 693

 Score = 1047 bits (2709), Expect = 0.0,   Method: Composition-based stats.
 Identities = 693/693 (100%), Positives = 693/693 (100%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG
Sbjct: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW
Sbjct: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI
Sbjct: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD
Sbjct: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP
Sbjct: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE
Sbjct: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
           IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV
Sbjct: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
           PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG
Sbjct: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD
Sbjct: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL
Sbjct: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
>gb|AAU09698.1| YDR234W [Saccharomyces cerevisiae]
          Length = 693

 Score = 1045 bits (2702), Expect = 0.0,   Method: Composition-based stats.
 Identities = 692/693 (99%), Positives = 693/693 (100%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG
Sbjct: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW
Sbjct: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI
Sbjct: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD
Sbjct: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP
Sbjct: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE
Sbjct: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
           IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV
Sbjct: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
           PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSRE+AATALLAKGINLVVSGSFG
Sbjct: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSRERAATALLAKGINLVVSGSFG 600

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD
Sbjct: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL
Sbjct: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
>gb|EDN60567.1| homoaconitase [Saccharomyces cerevisiae YJM789]
          Length = 693

 Score = 1044 bits (2700), Expect = 0.0,   Method: Composition-based stats.
 Identities = 688/693 (99%), Positives = 688/693 (99%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLRSTT TRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRSTTLTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGATKIKNPSQIV TLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG
Sbjct: 61  WPVALKFMGLGATKIKNPSQIVNTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLNM VASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 121 IGHQIMIEEGYAFPLNMAVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW
Sbjct: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKI KADKDAHYAKKLI
Sbjct: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKILKADKDAHYAKKLI 300

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD
Sbjct: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP
Sbjct: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKI SPAEVLSTSEIPFSGVKTE
Sbjct: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKIGSPAEVLSTSEIPFSGVKTE 480

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
           IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV
Sbjct: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
           PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG
Sbjct: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD
Sbjct: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL
Sbjct: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
>ref|XP_452878.1| unnamed protein product [Kluyveromyces lactis]
 sp|Q6CT61|LYS4_KLULA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAH01729.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
          Length = 693

 Score =  970 bits (2509), Expect = 0.0,   Method: Composition-based stats.
 Identities = 550/695 (79%), Positives = 613/695 (88%), Gaps = 4/695 (0%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           M R     R F +SRA   GQN+TEKIVQ +AV LPEGK V SGDYVSIKPAHCMSHDNS
Sbjct: 1   MFRVQRL-RMFSTSRALYAGQNMTEKIVQRHAVGLPEGKTVVSGDYVSIKPAHCMSHDNS 59

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGA+ IKNP Q+V TLDHD+QNKSEKNLTKYKNIENFAKKH ID YPAGRG
Sbjct: 60  WPVALKFMGLGASTIKNPRQVVNTLDHDVQNKSEKNLTKYKNIENFAKKHGIDFYPAGRG 119

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPL MTVASDSHSNTYGG+G+LGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 120 IGHQIMIEEGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIPPVA 179

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKG+LP G+SGKDIIVALCG+FN DQVLNHAIEFTGDSL+ +PID+RLTIANMTTEW
Sbjct: 180 QVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEW 239

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVD  L+D+Y+NRL K+G NNHPRIN   I  L+ K+   +AD DA YAKKLI
Sbjct: 240 GALSGLFPVDNVLLDFYRNRLTKVG-NNHPRINEARINELQAKSDSLQADPDAKYAKKLI 298

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDL+TLTHYVSGPNSVK+S+TV DLS+QDIK+NKAYLVSCTNSRLSDL+SAA+VVCP+GD
Sbjct: 299 IDLSTLTHYVSGPNSVKISSTVDDLSKQDIKVNKAYLVSCTNSRLSDLESAANVVCPSGD 358

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           +N+V+KVA GVEFY+AAASSE+EA+AR +GAW+KLL AGC+PLP+GCGPCIGLG GLLE 
Sbjct: 359 INQVHKVAEGVEFYIAAASSEVEAEARATGAWQKLLNAGCLPLPAGCGPCIGLGTGLLEE 418

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           G+VGISATNRNFKGRMGSKDALAYLASP+VVAASA+LGKI SPAEVL T +  F+GV   
Sbjct: 419 GQVGISATNRNFKGRMGSKDALAYLASPSVVAASAILGKIGSPAEVLGTKDPNFTGVVAT 478

Query: 481 IIENPVV--EEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQD 538
           + + P    + +  A       SVEILEGFP E SGELVLCDADNINTDGIYPGKYTYQD
Sbjct: 479 VEDAPATSADGKDVADESGASGSVEILEGFPSEISGELVLCDADNINTDGIYPGKYTYQD 538

Query: 539 DVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGS 598
           DVPKE MA+VCMENYD +F+TK +PGDI++SGFNFGTGSSREQAATA+LAKGI LVVSGS
Sbjct: 539 DVPKETMAKVCMENYDPDFQTKANPGDILISGFNFGTGSSREQAATAILAKGIKLVVSGS 598

Query: 599 FGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGS 658
           FGNIF RNSINNALLTLEIPALI  LR++Y+ APKELTRRTGWFLKWDV+ AKV VTEGS
Sbjct: 599 FGNIFFRNSINNALLTLEIPALINMLRDRYKDAPKELTRRTGWFLKWDVSQAKVYVTEGS 658

Query: 659 LDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           ++GP++LEQKVGELGKNLQEIIVKGGLE WVKSQL
Sbjct: 659 VNGPIVLEQKVGELGKNLQEIIVKGGLESWVKSQL 693
>ref|XP_448693.1| unnamed protein product [Candida glabrata]
 sp|Q6FM51|LYS4_CANGA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAG61656.1| unnamed protein product [Candida glabrata CBS 138]
          Length = 689

 Score =  927 bits (2396), Expect = 0.0,   Method: Composition-based stats.
 Identities = 537/687 (78%), Positives = 592/687 (86%), Gaps = 1/687 (0%)

Query: 7   FTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALK 66
             RSFH      +GQNLTEKIVQ Y+V L  GK VHSGDYVSIKPAH MSHDNSWPVALK
Sbjct: 4   LRRSFHVYTRLQRGQNLTEKIVQQYSVGLAPGKRVHSGDYVSIKPAHVMSHDNSWPVALK 63

Query: 67  FMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIM 126
           FM LGA  +K+P QIV TLDHDIQNKS+KNLTKY+NIE+FAKKH ID YPAGRGIGHQIM
Sbjct: 64  FMNLGARTVKDPRQIVNTLDHDIQNKSDKNLTKYRNIESFAKKHGIDFYPAGRGIGHQIM 123

Query: 127 IEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKG 186
           +EEGYAFPLN+TVASDSHSNTYGG+G+LGTP+VRTDAAAIWATGQTWWQIPPVAQVE KG
Sbjct: 124 VEEGYAFPLNLTVASDSHSNTYGGMGALGTPVVRTDAAAIWATGQTWWQIPPVAQVEFKG 183

Query: 187 QLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGL 246
           +L + VSGKDIIVALCG+FN DQVLNHAIEFTGD++  LP+D RLTIANMTTEWGALSGL
Sbjct: 184 KLHESVSGKDIIVALCGVFNKDQVLNHAIEFTGDAIKHLPVDFRLTIANMTTEWGALSGL 243

Query: 247 FPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATL 306
           FPVD TLI+WYKNRL  +G N HPRIN  TI+ LE+KAK+ KAD DA YAKKL+IDL+TL
Sbjct: 244 FPVDDTLINWYKNRLNIVGPN-HPRINETTIKNLEDKAKVFKADSDAVYAKKLVIDLSTL 302

Query: 307 THYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNK 366
           THYVSGPNSVKVSNTVQDL++ +IKINKAYLVSCTN+RLSDL+SAA VVCPTGDL+KVNK
Sbjct: 303 THYVSGPNSVKVSNTVQDLARDNIKINKAYLVSCTNARLSDLESAAKVVCPTGDLSKVNK 362

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           VA GVEFY AAASSEIE +A + G W+ LL AGC PLPSGCGPCIGLGAGLLEPGEVGIS
Sbjct: 363 VADGVEFYFAAASSEIEKEAAEKGIWQALLAAGCKPLPSGCGPCIGLGAGLLEPGEVGIS 422

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPV 486
           ATNRNFKGRMGSKDALAYLASPAVVAASAVLG+I SPAEV    ++  SG+  E +    
Sbjct: 423 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGRIGSPAEVWGIEDVKSSGLLAEELACNT 482

Query: 487 VEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMA 546
                   +E     VE+LEGFP E  GELVLCDADN+NTDGIYPGKYTYQDDV +E MA
Sbjct: 483 ETSTATPVSEGSAAKVEMLEGFPEEIVGELVLCDADNVNTDGIYPGKYTYQDDVSRETMA 542

Query: 547 QVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRN 606
           QVCMENYD EF +K + GDI+VSGFNFGTGSSREQAAT+LLAKGINLVV+GSF N FSRN
Sbjct: 543 QVCMENYDGEFGSKANAGDILVSGFNFGTGSSREQAATSLLAKGINLVVAGSFSNTFSRN 602

Query: 607 SINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILE 666
           SINNALLTLEIP L++KLR K++ APKELTRRTGWFLKWDV +AKV VTEGS DG V+LE
Sbjct: 603 SINNALLTLEIPTLVEKLRSKFENAPKELTRRTGWFLKWDVPNAKVYVTEGSPDGQVLLE 662

Query: 667 QKVGELGKNLQEIIVKGGLEGWVKSQL 693
           QKVGELGKNLQEII+KGGLEGWVKSQL
Sbjct: 663 QKVGELGKNLQEIIIKGGLEGWVKSQL 689
>ref|XP_717326.1| homoaconitase [Candida albicans SC5314]
 ref|XP_717250.1| homoaconitase [Candida albicans SC5314]
 sp|Q5A644|LYS4_CANAL Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|EAK98277.1| potential homoaconitase [Candida albicans SC5314]
 gb|EAK98354.1| potential homoaconitase [Candida albicans SC5314]
          Length = 684

 Score =  926 bits (2394), Expect = 0.0,   Method: Composition-based stats.
 Identities = 484/695 (69%), Positives = 567/695 (81%), Gaps = 18/695 (2%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNL-PEGKVVHSGDYVSIKPAHCMSHDN 59
           MLR     RSF ++   L+GQNLTEKIVQ YAV L P  K V+SGDYV+IKPAHCMSHDN
Sbjct: 2   MLR----FRSFSTTTHLLRGQNLTEKIVQKYAVGLQPSSKKVYSGDYVTIKPAHCMSHDN 57

Query: 60  SWPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGR 119
           SWPVA KFM LGA+K+K+  QIV TLDHD+QNKSE+NLTKY NIE FAK   ID YPAGR
Sbjct: 58  SWPVATKFMNLGASKVKDNRQIVCTLDHDVQNKSEQNLTKYTNIEKFAKSQGIDFYPAGR 117

Query: 120 GIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPV 179
           GIGHQIMIEEGYAFPLN+TVASDSHSNTYGG+G+LGTPIVRTDAA+IWATGQTWWQIPPV
Sbjct: 118 GIGHQIMIEEGYAFPLNLTVASDSHSNTYGGIGALGTPIVRTDAASIWATGQTWWQIPPV 177

Query: 180 AQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGD-SLNALPIDHRLTIANMTT 238
           A+VEL GQLP+GV+GKDIIVALCG+FNND+VLNHAIEF GD +++ LPID+RLTIANMTT
Sbjct: 178 AKVELIGQLPKGVTGKDIIVALCGIFNNDEVLNHAIEFVGDDAISKLPIDYRLTIANMTT 237

Query: 239 EWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKK 298
           EWGALSGLFPVD+TL+++Y+NRL+KL   +HPRIN +TI  L        +D DA YAK 
Sbjct: 238 EWGALSGLFPVDETLVEFYQNRLKKLNKPDHPRINNQTIDQLIN--NKLTSDNDAVYAKH 295

Query: 299 LIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPT 358
           L IDL++L+ Y+SGPNSVK+SN++ DLSQQ+I INKAYLVSCTNSRLSD+Q+AAD++   
Sbjct: 296 LQIDLSSLSPYISGPNSVKISNSLYDLSQQNIAINKAYLVSCTNSRLSDIQAAADII--- 352

Query: 359 GDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLL 418
               K +KV P VEFYVAAASS ++ DA +SGAW+ +L AG  PLP+GCGPCIGLG GLL
Sbjct: 353 ----KGHKVNPNVEFYVAAASSLVQKDAEQSGAWQTILDAGAKPLPAGCGPCIGLGTGLL 408

Query: 419 EPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVK 478
           + GEVGISATNRNFKGRMGSKDALAYLASP VVAASAVLGKI  P E+          + 
Sbjct: 409 KDGEVGISATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGGPEELNGEPVKQAPRII 468

Query: 479 TEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQD 538
             I        E  + +E    S++IL GFP+   GEL+LC+ADNINTDGIYPGKYTYQD
Sbjct: 469 KSIETESNSANEAESTSEEASGSIDILPGFPQSIEGELILCNADNINTDGIYPGKYTYQD 528

Query: 539 DVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGS 598
           D+ KE+MA+VCMENYD++F +K  PGDI++SG+NFGTGSSREQAAT +LA+G+ L+V+GS
Sbjct: 529 DITKEQMAKVCMENYDSQFYSKTKPGDIIISGYNFGTGSSREQAATCILARGMKLIVAGS 588

Query: 599 FGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGS 658
           FGNIFSRNSINNALLTLEIP LI KLR++Y+G   ELT RTGWFLKWDV  A+V V +G 
Sbjct: 589 FGNIFSRNSINNALLTLEIPDLINKLRQQYEGND-ELTIRTGWFLKWDVTKAQVTVVDG- 646

Query: 659 LDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            D  +IL QKVGELG NLQ+IIVKGGLEGWVKS+L
Sbjct: 647 -DDNLILTQKVGELGTNLQDIIVKGGLEGWVKSEL 680
>ref|XP_460673.1| hypothetical protein DEHA0F08019g [Debaryomyces hansenii CBS767]
 sp|Q6BM98|LYS4_DEBHA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAG89007.1| unnamed protein product [Debaryomyces hansenii CBS767]
          Length = 688

 Score =  925 bits (2391), Expect = 0.0,   Method: Composition-based stats.
 Identities = 476/689 (69%), Positives = 555/689 (80%), Gaps = 16/689 (2%)

Query: 5   TTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA 64
            T  R   SS    +GQNLTEKIVQ YAV L + K V SGDYV+IKPAHCMSHDNSWPVA
Sbjct: 14  KTGARCLSSSSILYRGQNLTEKIVQKYAVGLADDKKVFSGDYVTIKPAHCMSHDNSWPVA 73

Query: 65  LKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQ 124
            KFMGLGAT + +  QIV TLDHD+QNKSEKNL KY NIENFAK+  ID YPAGRGIGHQ
Sbjct: 74  TKFMGLGATNVHDNRQIVCTLDHDVQNKSEKNLEKYHNIENFAKEQGIDFYPAGRGIGHQ 133

Query: 125 IMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVEL 184
           IMIEEGYA+PLN+TVASDSHSNTYGG+GSLGTPIVRTDAA+IWATGQTWWQIPPVA+VEL
Sbjct: 134 IMIEEGYAYPLNLTVASDSHSNTYGGIGSLGTPIVRTDAASIWATGQTWWQIPPVAKVEL 193

Query: 185 KGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALS 244
            GQLP+G +GKDIIVALCG+FNND+VLNHAIEFTG+ +  L +D+RLTIANMTTEWGALS
Sbjct: 194 VGQLPKGATGKDIIVALCGIFNNDEVLNHAIEFTGEGVKNLSVDYRLTIANMTTEWGALS 253

Query: 245 GLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLA 304
           GLFPVD+TL+++Y  R++KL    HPR+N  T++ L E      +D DA YAK L++DL+
Sbjct: 254 GLFPVDETLVNFYDERVKKL-PQPHPRVNENTVKNLSE--NKVNSDNDAVYAKHLVVDLS 310

Query: 305 TLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKV 364
           +L+ Y+SGPNSVKVS ++ DLS+Q+IKINKAYLVSCTNSRLSD+++AAD++       K 
Sbjct: 311 SLSPYISGPNSVKVSTSLHDLSKQNIKINKAYLVSCTNSRLSDIKAAADII-------KG 363

Query: 365 NKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVG 424
           +KVA GVEFYVAAASS ++ DA   GAW+ ++ AG  PLP+GCGPCIGLG GLLE GEVG
Sbjct: 364 HKVAEGVEFYVAAASSNVQKDAEAIGAWQDIIDAGAKPLPAGCGPCIGLGTGLLEDGEVG 423

Query: 425 ISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIEN 484
           ISATNRNFKGRMGSKDALAYLASP VVAASAVLGKI  P E+          +   I  N
Sbjct: 424 ISATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGGPEELQGNPVPTNPEIVRSITSN 483

Query: 485 PVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEK 544
              E       +A   SV++L+GFP+   GEL+LCDADNINTDGIYPGKYTYQDD+P+ K
Sbjct: 484 ESTET---VDPDASGSSVDVLDGFPQSIEGELILCDADNINTDGIYPGKYTYQDDIPRSK 540

Query: 545 MAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFS 604
           MA+VCMENYD+EF+ K   GDI++SG+NFGTGSSREQAATA+LA+ + LVV+GSFGNIFS
Sbjct: 541 MAEVCMENYDSEFKQKTKAGDIIISGYNFGTGSSREQAATAILARDMKLVVAGSFGNIFS 600

Query: 605 RNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVI 664
           RNSINNALLTLEIPALI KLREKY     ELT RTGWFLKWDV   +V V++   +G +I
Sbjct: 601 RNSINNALLTLEIPALINKLREKYA-QSNELTIRTGWFLKWDVTKNQVTVSDS--EGNLI 657

Query: 665 LEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           L QKVGELG NLQ+IIVKGGLEGWVK+QL
Sbjct: 658 LTQKVGELGTNLQDIIVKGGLEGWVKAQL 686
>sp|Q2HZ33|LYS4_CANPA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|ABC94604.1| homoaconitase [Candida parapsilosis]
          Length = 688

 Score =  920 bits (2378), Expect = 0.0,   Method: Composition-based stats.
 Identities = 486/698 (69%), Positives = 559/698 (80%), Gaps = 29/698 (4%)

Query: 7   FTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALK 66
             R   +S     GQNLTEKIVQ YAVNLP  K+VH+GDYV+IKPAHCMSHDNSWPVA K
Sbjct: 5   LHRFISTSTPLRSGQNLTEKIVQKYAVNLPPNKLVHTGDYVTIKPAHCMSHDNSWPVATK 64

Query: 67  FMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIM 126
           FMGLGA ++K+  QIV TLDHD+QNK+EKNL KY NIE FAK+  ID YPAGRGIGHQIM
Sbjct: 65  FMGLGAKRVKDNRQIVCTLDHDVQNKTEKNLAKYANIERFAKEQGIDFYPAGRGIGHQIM 124

Query: 127 IEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKG 186
           IEEGYAFPLN+TVASDSHSNTYGG+GSLGTPIVRTDAA+IWAT QTWWQIPPVA+VELKG
Sbjct: 125 IEEGYAFPLNLTVASDSHSNTYGGVGSLGTPIVRTDAASIWATVQTWWQIPPVAKVELKG 184

Query: 187 QLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGL 246
            L  GV+GKDIIVALCG+FNND+VLNHAIEF GD +  LPID+RLTIANMTTEWGALSGL
Sbjct: 185 NLQNGVTGKDIIVALCGVFNNDEVLNHAIEFVGDGVENLPIDYRLTIANMTTEWGALSGL 244

Query: 247 FPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATL 306
           FP+D  LI++Y+ RLQKLG N HPRIN  TI AL   +    +D+DA YAK L+IDL TL
Sbjct: 245 FPIDDKLIEFYEGRLQKLGPN-HPRINKDTIEALRRGS--LASDEDAKYAKHLVIDLNTL 301

Query: 307 THYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNK 366
           + YVSGPNSVKVSN +  LSQ +I INKAYLVSCTNSRLSD+Q+AADV+       K +K
Sbjct: 302 SPYVSGPNSVKVSNPLSKLSQDNIAINKAYLVSCTNSRLSDIQAAADVL-------KGHK 354

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           V P VEFYVAAASS ++ DA  +GAW+ ++ AG  PLP+GCGPCIGLG GLL+ GEVGIS
Sbjct: 355 VHPNVEFYVAAASSLVQQDAEAAGAWQTIIDAGAKPLPAGCGPCIGLGTGLLKDGEVGIS 414

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPA-----------EVLSTSEIPFS 475
           ATNRNFKGRMGSKDALAYLASP VVAASAVLGKI +P            E++ + ++P S
Sbjct: 415 ATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGAPEEIDGKPVNASPEIVKSIDLPKS 474

Query: 476 GVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYT 535
              T         EE  ++ +  + SVE+L GFP+   GEL+LC+ADNINTDGIYPGKYT
Sbjct: 475 SGNTG-----ATSEEPISEDDTSEASVEVLPGFPKSIQGELILCNADNINTDGIYPGKYT 529

Query: 536 YQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVV 595
           YQDD+ +E+MA+VCMENYD EF+TK    DI++SG+NFGTGSSREQAAT +LA+G+ LVV
Sbjct: 530 YQDDISREQMAEVCMENYDPEFKTKTKSDDIIISGYNFGTGSSREQAATCILARGMKLVV 589

Query: 596 SGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVT 655
           +GSFGNIFSRNSINNALLTLEIP LI+KLR KY G   ELT RTGWFLKWDV  A V V 
Sbjct: 590 AGSFGNIFSRNSINNALLTLEIPELIEKLRVKYDG-VNELTIRTGWFLKWDVTKALVTVA 648

Query: 656 EGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           +  LDG VIL+QKVGELG NLQ+IIVKGGLEGWVKS+L
Sbjct: 649 D--LDGEVILQQKVGELGTNLQDIIVKGGLEGWVKSEL 684
>ref|XP_001383888.2| homoaconitase [Pichia stipitis CBS 6054]
 gb|ABN65859.2| homoaconitase [Pichia stipitis CBS 6054]
          Length = 677

 Score =  915 bits (2367), Expect = 0.0,   Method: Composition-based stats.
 Identities = 489/693 (70%), Positives = 564/693 (81%), Gaps = 20/693 (2%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLR     R   +S   L+GQNLTEKIVQ YAVNLP GK V SGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRVNI--RGLATSARLLRGQNLTEKIVQRYAVNLPAGKQVFSGDYVSIKPAHCMSHDNS 58

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVA KFMGLGATK+K+  QIV TLDHD+QNKSEKNL KY+NIE FAK+  ID YPAGRG
Sbjct: 59  WPVATKFMGLGATKVKDNRQIVCTLDHDVQNKSEKNLEKYRNIEQFAKEQGIDFYPAGRG 118

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLN+TVASDSHSNTYGG+GSLGTPIVRTDAA+IWATGQTWWQIPPVA
Sbjct: 119 IGHQIMIEEGYAFPLNLTVASDSHSNTYGGVGSLGTPIVRTDAASIWATGQTWWQIPPVA 178

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           +VEL+G+LP GV+GKDIIVALCG FN D+VLNHAIEF GD +  L ID+RLTIANMTTEW
Sbjct: 179 KVELQGKLPAGVTGKDIIVALCGAFNKDEVLNHAIEFVGDGIEHLSIDYRLTIANMTTEW 238

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVD  L+DWY++       + HPR+N KT+ ALE+     ++D DA YAK L+
Sbjct: 239 GALSGLFPVDARLLDWYRSERLAKLGSGHPRVNDKTVSALEK--NPVQSDSDAVYAKHLV 296

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           +DL++LT Y+SGPNSVK+SN++ DL +QDI INKAYLVSCTNSRLSD+Q+AADV+     
Sbjct: 297 VDLSSLTPYISGPNSVKISNSLADLVEQDIPINKAYLVSCTNSRLSDIQAAADVI----- 351

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
             + +KVAPGVEFYVAAASS ++ DA  +GAW+ +L+AG  PLP+GCGPCIGLG GLL+ 
Sbjct: 352 --RGHKVAPGVEFYVAAASSNVQKDAEAAGAWKTILEAGAKPLPAGCGPCIGLGTGLLKD 409

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASP VVAASAVLG+I  P E+    E        E
Sbjct: 410 GEVGISATNRNFKGRMGSKDALAYLASPEVVAASAVLGRIGGPQEL----EGKSVLSTRE 465

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
           II+   +EE   ++  A   +VE+LEGFP+   GEL+LCDADNINTDGIYPGKYTYQDD+
Sbjct: 466 IIK--TIEETKVSEDAATGGAVEVLEGFPKVIEGELILCDADNINTDGIYPGKYTYQDDI 523

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
           P+EKMA+VCMENYDAEF  K   GDI++SG+NFGTGSSREQAATA+LA+G+ LVV+GSFG
Sbjct: 524 PREKMAEVCMENYDAEFNGKTKAGDIIISGYNFGTGSSREQAATAILARGMKLVVAGSFG 583

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIP LI  LR KY G+  ELT RTGW LKWDV  A V V     +
Sbjct: 584 NIFSRNSINNALLTLEIPDLINNLRAKYAGSD-ELTVRTGWILKWDVTTATVEV--KDSE 640

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           G V+L+QKVGELG NLQ+IIVKGGLEGWV+S+L
Sbjct: 641 GNVVLKQKVGELGTNLQDIIVKGGLEGWVRSEL 673
>ref|XP_001646008.1| hypothetical protein Kpol_1031p57 [Vanderwaltozyma polyspora DSM
           70294]
 gb|EDO18150.1| hypothetical protein Kpol_1031p57 [Vanderwaltozyma polyspora DSM
           70294]
          Length = 689

 Score =  914 bits (2363), Expect = 0.0,   Method: Composition-based stats.
 Identities = 518/695 (74%), Positives = 582/695 (83%), Gaps = 9/695 (1%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLR   F           +GQNLTEKIVQ YAV LPEGK V SGDYVSI+P++CMSHDNS
Sbjct: 1   MLRFKRFFSEGS--IRLTRGQNLTEKIVQRYAVELPEGKKVFSGDYVSIRPSYCMSHDNS 58

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WP+ALKFMGLGATK+K P QIV TLDHD+QNKSEKNLTKY+NIENFAKKH    YPAGRG
Sbjct: 59  WPIALKFMGLGATKLKYPDQIVNTLDHDVQNKSEKNLTKYRNIENFAKKHGSHFYPAGRG 118

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLN+TVASDSHSN YGG+G LGTPIVRTDAA+IWATGQTWWQIPPVA
Sbjct: 119 IGHQIMIEEGYAFPLNLTVASDSHSNIYGGVGCLGTPIVRTDAASIWATGQTWWQIPPVA 178

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKG+LP GVSGKDIIVALCGLFN+DQVLNHAIEFTGDS+  L ID+RLTIANMTTEW
Sbjct: 179 QVELKGELPTGVSGKDIIVALCGLFNDDQVLNHAIEFTGDSIKNLSIDNRLTIANMTTEW 238

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVD T+I WYK R+ K+G  +   IN K I  LE+ A+  KAD ++ Y KKL 
Sbjct: 239 GALSGLFPVDSTVIQWYKERINKVGEGH--IINSKAIEELEQNAQKLKADSNSKYDKKLT 296

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDL+TLT+YVSGPNSVK+SN V+DLS+QDIKINKAYLVSCTNSRLSD+++AADVVCPTG+
Sbjct: 297 IDLSTLTYYVSGPNSVKISNPVEDLSKQDIKINKAYLVSCTNSRLSDIEAAADVVCPTGN 356

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           +  V KVAPGV FY+AAASSE+E +AR SGAW+KLLKAGCI LP+GCGPCIGLG GLLE 
Sbjct: 357 IEDVKKVAPGVNFYIAAASSEVEKEARTSGAWDKLLKAGCIALPAGCGPCIGLGTGLLEA 416

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASPAVVAASA+ GKI SP E L      ++ VKT 
Sbjct: 417 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASALAGKIVSPNEALGIESCKYASVKTS 476

Query: 481 IIENPVVEEEVNAQTEAPKQ--SVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQD 538
                ++EEE +  +  P +   VEILEGFP E SGELV CDADNINTDGIYPGKYTYQD
Sbjct: 477 ---EQILEEETSGTSSGPTEASRVEILEGFPSEISGELVFCDADNINTDGIYPGKYTYQD 533

Query: 539 DVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGS 598
           D+ KE MA+VCMENYD EF+TK   GDI++SGFNFGTGSSREQAAT +LA+GINLVVSGS
Sbjct: 534 DISKEMMAEVCMENYDPEFQTKTKTGDIIISGFNFGTGSSREQAATCILARGINLVVSGS 593

Query: 599 FGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGS 658
           FGNIFSRNSINN LLT+E+P LI++LR KY+    ELTRRTGWF KWDVA+  V V EGS
Sbjct: 594 FGNIFSRNSINNGLLTVEVPKLIEQLRSKYKDDTPELTRRTGWFFKWDVANKNVTVREGS 653

Query: 659 LDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           L G ++ EQ++ ELGKNLQEIIVKGGLEGWVKS+L
Sbjct: 654 LTGTIVFEQEIPELGKNLQEIIVKGGLEGWVKSKL 688
>ref|XP_503471.1| hypothetical protein [Yarrowia lipolytica]
 sp|Q6C791|LYS4_YARLI Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAG79050.1| unnamed protein product [Yarrowia lipolytica CLIB122]
          Length = 687

 Score =  912 bits (2358), Expect = 0.0,   Method: Composition-based stats.
 Identities = 482/694 (69%), Positives = 556/694 (80%), Gaps = 17/694 (2%)

Query: 2   LRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSW 61
           +  T   R + + R     QNLTEKIVQ YAV LPEGK V SGDYVSI+P+HCM+HDNSW
Sbjct: 9   VTQTLLVRRYSTKRI---PQNLTEKIVQRYAVGLPEGKQVQSGDYVSIRPSHCMTHDNSW 65

Query: 62  PVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGI 121
           PVA KF GLGA  +K+  Q+V TLDHD+QNKSEKNL KY NIENFA +  ID YPAGRGI
Sbjct: 66  PVATKFKGLGAKAVKDNRQVVMTLDHDVQNKSEKNLEKYANIENFAGEQGIDFYPAGRGI 125

Query: 122 GHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQ 181
           GHQ+M+EEGYAFP N+TVASDSHSN YGG+G LGTPIVRTDAA++WATGQTWWQIPPVA+
Sbjct: 126 GHQVMVEEGYAFPYNLTVASDSHSNMYGGIGCLGTPIVRTDAASVWATGQTWWQIPPVAR 185

Query: 182 VELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWG 241
           VELKGQLP GV GKD+I+ALCG+FNND+VLNHAIEF GD +  L +D RLTIANMTTEWG
Sbjct: 186 VELKGQLPAGVFGKDVIIALCGIFNNDEVLNHAIEFVGDGVEHLSVDERLTIANMTTEWG 245

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLII 301
           AL+GLFPVD+TL  WY+ RL +L    H R+N  T+ AL++     +AD DA YAK L I
Sbjct: 246 ALTGLFPVDETLRQWYEYRLTRL-PQPHARVNDGTVAALKD---AVQADTDAKYAKNLTI 301

Query: 302 DLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDL 361
           DL+TL+ ++SGPNSVKV N++ DLS QDIKINKAYLVSCTNSRLSD+++AA+V+      
Sbjct: 302 DLSTLSPFLSGPNSVKVYNSLADLSAQDIKINKAYLVSCTNSRLSDIEAAANVI------ 355

Query: 362 NKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPG 421
            K NKVA GVEFYVAAASS ++ DA  SGAW+ L+ AG  PLP+GCGPCIGLG GLLE G
Sbjct: 356 -KNNKVAEGVEFYVAAASSFVQKDAEASGAWQTLINAGAKPLPAGCGPCIGLGTGLLEDG 414

Query: 422 EVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEI 481
           EVGISATNRNFKGRMGSKDALAYLASP VVAASAVLGKI  P EV  +      GV + I
Sbjct: 415 EVGISATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGFPEEVYGSPVPGAKGVSSSI 474

Query: 482 --IENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDD 539
              E    E +  A    P  S  +L+GFP + +GELVLCDADNINTDGIYPGKYTYQDD
Sbjct: 475 SVTEAVEAEADAEAAESDPAPSGGVLDGFPAQITGELVLCDADNINTDGIYPGKYTYQDD 534

Query: 540 VPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSF 599
           VP+EKMA+VCMENYD +F +K   GDI+VSGFNFGTGSSREQAAT +LA+ + LV++GSF
Sbjct: 535 VPREKMAEVCMENYDPDFGSKTGAGDIIVSGFNFGTGSSREQAATCILARDMQLVIAGSF 594

Query: 600 GNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSL 659
           GNIFSRNSINNALLTLEIPALI KLR++Y+G P ELTRRTGWF  WDV  A V VT+G  
Sbjct: 595 GNIFSRNSINNALLTLEIPALINKLRKRYEGQPAELTRRTGWFATWDVPAATVTVTDGK- 653

Query: 660 DGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           +GPVIL+QKVGELG+NLQEIIVKGGLEGWVK+QL
Sbjct: 654 NGPVILKQKVGELGQNLQEIIVKGGLEGWVKAQL 687
>ref|XP_664125.1| LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate
           hydratase) [Aspergillus nidulans FGSC A4]
 gb|EAA57861.1| LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate
           hydratase) [Aspergillus nidulans FGSC A4]
          Length = 776

 Score =  911 bits (2355), Expect = 0.0,   Method: Composition-based stats.
 Identities = 419/729 (57%), Positives = 509/729 (69%), Gaps = 42/729 (5%)

Query: 3   RSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWP 62
            S     + +SS+A    Q LTEKIVQ Y+V LP+GK V SGDYV+I+P  CM+HDNSWP
Sbjct: 50  TSAALFSALNSSKAV--PQTLTEKIVQKYSVGLPQGKFVKSGDYVTIQPHRCMTHDNSWP 107

Query: 63  VALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIG 122
            ALKFM +GA+++ NP QIV TLDHD+QNKS+KNL KY+ IE FA +H ++ YPAGRGIG
Sbjct: 108 CALKFMSIGASRLHNPDQIVMTLDHDVQNKSDKNLKKYRQIEEFATQHGVEFYPAGRGIG 167

Query: 123 HQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQV 182
           HQIMIEEG+A+P  + VASDSHSN YGG+G LGTPIVRTDAA++WATG+TWWQIPPVA+V
Sbjct: 168 HQIMIEEGFAWPGTLAVASDSHSNMYGGVGCLGTPIVRTDAASVWATGKTWWQIPPVAKV 227

Query: 183 ELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEW 240
             KG LP GV+GKD+IVALCGLFN D VLNHAIEFTG  +++ +L +D RLTIANMTTEW
Sbjct: 228 TFKGVLPPGVTGKDVIVALCGLFNKDDVLNHAIEFTGSEETMRSLSVDTRLTIANMTTEW 287

Query: 241 GALSGLFPVDKTLIDWYKNR--LQKLGTNNHPRINPKTIRA-----LEEKAKIPKADKDA 293
           GALSGLFP+D  L  W + +     +G  + P       R       +       ADK A
Sbjct: 288 GALSGLFPIDSVLKGWLRGKATTAAMGLADGPFKTRAAERFTHPLLEQLFENPLTADKGA 347

Query: 294 HYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAAD 353
            YAK+L +DL++L+ YVSGPNSVKV+  +++L  Q+IK++KAYLVSCTNSR SD+ +AA 
Sbjct: 348 KYAKELFLDLSSLSPYVSGPNSVKVATPLKELEAQNIKVDKAYLVSCTNSRASDIAAAAK 407

Query: 354 VVCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCI 411
           V     + N     K+A GV+FY+AAAS   +  A  +G W+ LL+AG   LP+GCGPCI
Sbjct: 408 VFKEAAEKNGGKIPKIADGVKFYIAAASIPEQLAAEGNGDWQTLLEAGATQLPAGCGPCI 467

Query: 412 GLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSE 471
           G+G GLLEPGEVGISA+NRNFKGRMGS +A AYL SP VVAASA+ GK+S P    +   
Sbjct: 468 GMGQGLLEPGEVGISASNRNFKGRMGSTEAKAYLGSPEVVAASALSGKLSGPGWYQTPEG 527

Query: 472 I------PFSGVKTE---------------IIENPVVEEEVNAQTEAPKQS------VEI 504
                     G++ E                +++ V + E    +E P          EI
Sbjct: 528 WTEVIRGEGDGIREEDRMLTNEEALEKIIGQLDDLVADGEKRFASETPAVEESEQGLTEI 587

Query: 505 LEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPG 564
             GFP   SGELV CDADN+NTDGIYPGKYTYQDDVP E MA+VCMENYD EF T    G
Sbjct: 588 YPGFPERVSGELVFCDADNVNTDGIYPGKYTYQDDVPPETMARVCMENYDPEFSTTAKEG 647

Query: 565 DIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKL 624
           DI+VSGFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P L+ +L
Sbjct: 648 DILVSGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLVNRL 707

Query: 625 REKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGG 684
           RE +    K LTRRTGW L WDV  +++ V EG   G      KVGEL  N+QEII KGG
Sbjct: 708 RETFGSGDKVLTRRTGWTLTWDVRKSQIEVQEGP--GGPKWTHKVGELPPNVQEIIAKGG 765

Query: 685 LEGWVKSQL 693
           LE WVK+ +
Sbjct: 766 LEKWVKNAI 774
>ref|XP_001485749.1| hypothetical protein PGUG_01420 [Pichia guilliermondii ATCC 6260]
 gb|EDK37322.1| hypothetical protein PGUG_01420 [Pichia guilliermondii ATCC 6260]
          Length = 674

 Score =  907 bits (2344), Expect = 0.0,   Method: Composition-based stats.
 Identities = 478/685 (69%), Positives = 562/685 (82%), Gaps = 16/685 (2%)

Query: 9   RSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFM 68
           R F +    L+GQNLTEKIVQ YAV +  GK V SGDYV+IKPAHCMSHDNSWPVA KFM
Sbjct: 5   RQFSTGLRALRGQNLTEKIVQKYAVGVAPGKKVVSGDYVTIKPAHCMSHDNSWPVATKFM 64

Query: 69  GLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIE 128
           GLGATK+K+  Q+V TLDHD+QN+SE N+ KY NIE FA +  ID YPAGRGIGHQIMIE
Sbjct: 65  GLGATKVKDNRQVVCTLDHDVQNRSESNMKKYANIEKFATEQGIDFYPAGRGIGHQIMIE 124

Query: 129 EGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQL 188
           EGYAFP N+TVASD HSNTYGG+GSLGTPIVRTDAAAIWATGQTWWQIPPVA+VE  G+L
Sbjct: 125 EGYAFPHNLTVASDLHSNTYGGVGSLGTPIVRTDAAAIWATGQTWWQIPPVAKVEFTGEL 184

Query: 189 PQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFP 248
            +GV+GKD+IVALCG+FN D+VLNHAIEF GD + +LPID+RLTIANMTTEWGALSGLFP
Sbjct: 185 SEGVTGKDVIVALCGVFNQDEVLNHAIEFVGDGVKSLPIDYRLTIANMTTEWGALSGLFP 244

Query: 249 VDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           VD+T+ID+Y+ R+Q+L    H RIN  T+  L   AK   AD DA YAK LI+DL+T++ 
Sbjct: 245 VDQTVIDFYEGRMQRL-QQPHERINSDTVGKLAANAKEMAADSDAKYAKHLIVDLSTISP 303

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVA 368
            VSGPNSVKV++++ DL+QQDIKINKAYLVSCTNSRLSD+Q+AAD+V       + + +A
Sbjct: 304 CVSGPNSVKVASSLHDLAQQDIKINKAYLVSCTNSRLSDIQAAADIV-------RGHTIA 356

Query: 369 PGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISAT 428
            GVEFYVAAASS+++ DA  +GAW+ ++ AG  PLP+GCGPCIGLG GLLEPGEVGISAT
Sbjct: 357 DGVEFYVAAASSQVQQDAEAAGAWQTIIDAGAKPLPAGCGPCIGLGTGLLEPGEVGISAT 416

Query: 429 NRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVE 488
           NRNFKGRMGSKDALAYLASP VVAASA+LG+I  P E+ S S+I         ++     
Sbjct: 417 NRNFKGRMGSKDALAYLASPEVVAASAILGRIGGPEEI-SGSKIAAPA----TLKRSTSV 471

Query: 489 EEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQV 548
              +++  A    V+I+ GFP+E +GEL+LC+ADNINTDGIYPGKYTYQDDVPKEKMAQV
Sbjct: 472 STSDSEDSATGAGVDIIPGFPQELTGELILCNADNINTDGIYPGKYTYQDDVPKEKMAQV 531

Query: 549 CMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSI 608
           CMENYD EF +K  PGDI++SG+NFGTGSSREQAATA+LA+G+ LVV+GSFGNIFSRNSI
Sbjct: 532 CMENYDGEFYSKTKPGDIIISGYNFGTGSSREQAATAILARGMQLVVAGSFGNIFSRNSI 591

Query: 609 NNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQK 668
           NNALLTLEIPALI KLR+KY G  KELT RTGWFLKWDV  A+V VT+   D  VI++QK
Sbjct: 592 NNALLTLEIPALIDKLRQKYAG-DKELTIRTGWFLKWDVPKAQVTVTDA--DNKVIMQQK 648

Query: 669 VGELGKNLQEIIVKGGLEGWVKSQL 693
           VGELG NLQ+IIVKGGLEGWVK+Q+
Sbjct: 649 VGELGTNLQDIIVKGGLEGWVKAQI 673
>sp|Q92412|LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAA67943.1| homoaconitase [Emericella nidulans]
          Length = 775

 Score =  906 bits (2342), Expect = 0.0,   Method: Composition-based stats.
 Identities = 418/729 (57%), Positives = 508/729 (69%), Gaps = 43/729 (5%)

Query: 3   RSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWP 62
            S     + +SS+A    Q LTEKIVQ Y+V LP+GK V SGDYV+I+P  CM+HDNSWP
Sbjct: 50  TSAALFSALNSSKAV--PQTLTEKIVQKYSVGLPQGKFVKSGDYVTIQPHRCMTHDNSWP 107

Query: 63  VALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIG 122
            ALKFM +GA+++ NP QIV TLDHD+QNKS+KNL KY+ IE FA +H ++ YPAGRGIG
Sbjct: 108 CALKFMSIGASRLHNPDQIVMTLDHDVQNKSDKNLKKYRQIEEFATQHGVEFYPAGRGIG 167

Query: 123 HQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQV 182
           HQIMIEEG+A+P  + VASDSHSN YGG+G LGTPIVRTDAA++WATG+TWWQIPPVA+V
Sbjct: 168 HQIMIEEGFAWPGTLAVASDSHSNMYGGVGCLGTPIVRTDAASVWATGKTWWQIPPVAKV 227

Query: 183 ELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEW 240
             KG LP GV+GKD+IVALCGLFN D VLNHAIEFTG  +++ +L +D RLTIANMTTEW
Sbjct: 228 TFKGVLPPGVTGKDVIVALCGLFNKDDVLNHAIEFTGSEETMRSLSVDTRLTIANMTTEW 287

Query: 241 GALSGLFPVDKTLIDWYKNR--LQKLGTNNHPRINPKTIRA-----LEEKAKIPKADKDA 293
           GALSGLFP+D  L  W + +     +G  + P       R       +       ADK A
Sbjct: 288 GALSGLFPIDSVLKGWLRGKATTAAMGLADGPFKTRAAERFTHPLLEQLFENPLTADKGA 347

Query: 294 HYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAAD 353
            YAK+L +DL++L+ YVSGPNSVKV+  +++L  Q+IK++KAYLVSCTNSR SD+ +AA 
Sbjct: 348 KYAKELFLDLSSLSPYVSGPNSVKVATPLKELEAQNIKVDKAYLVSCTNSRASDIAAAAK 407

Query: 354 VVCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCI 411
           V     + N     K+  GV+FY+AAAS   +  A  +G W+ LL+AG   LP+GCGPCI
Sbjct: 408 VFKEAAEKNGGKIPKIH-GVKFYIAAASIPEQLAAEGNGDWQTLLEAGATQLPAGCGPCI 466

Query: 412 GLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSE 471
           G+G GLLEPGEVGISA+NRNFKGRMGS +A AYL SP VVAASA+ GK+S P    +   
Sbjct: 467 GMGQGLLEPGEVGISASNRNFKGRMGSTEAKAYLGSPEVVAASALSGKLSGPGWYQTPEG 526

Query: 472 I------PFSGVKTE---------------IIENPVVEEEVNAQTEAPKQS------VEI 504
                     G++ E                +++ V + E    +E P          EI
Sbjct: 527 WTEVIRGEGDGIREEDRMLTNEEALEKIIGQLDDLVADGEKRFASETPAVEESEQGLTEI 586

Query: 505 LEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPG 564
             GFP   SGELV CDADN+NTDGIYPGKYTYQDDVP E MA+VCMENYD EF T    G
Sbjct: 587 YPGFPERVSGELVFCDADNVNTDGIYPGKYTYQDDVPPETMARVCMENYDPEFSTTAKEG 646

Query: 565 DIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKL 624
           DI+VSGFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P L+ +L
Sbjct: 647 DILVSGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLVNRL 706

Query: 625 REKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGG 684
           RE +    K LTRRTGW L WDV  +++ V EG   G      KVGEL  N+QEII KGG
Sbjct: 707 RETFGSGDKVLTRRTGWTLTWDVRKSQIEVQEGP--GGPKWTHKVGELPPNVQEIIAKGG 764

Query: 685 LEGWVKSQL 693
           LE WVK+ +
Sbjct: 765 LEKWVKNAI 773
>ref|XP_001523113.1| homoaconitase, mitochondrial precursor [Lodderomyces elongisporus
           NRRL YB-4239]
 gb|EDK47478.1| homoaconitase, mitochondrial precursor [Lodderomyces elongisporus
           NRRL YB-4239]
          Length = 688

 Score =  906 bits (2342), Expect = 0.0,   Method: Composition-based stats.
 Identities = 471/697 (67%), Positives = 556/697 (79%), Gaps = 23/697 (3%)

Query: 3   RSTTFTRSFHSSRAWLKGQNLTEKIVQSYAV-----NLPEGKVVHSGDYVSIKPAHCMSH 57
           R +   R F S     +GQNLTEKIVQ +A+     +  + K+VHSGDYV+IKP HCMSH
Sbjct: 4   RLSNAVRCFSSPAHLRQGQNLTEKIVQRFAILPATADGSQQKLVHSGDYVTIKPQHCMSH 63

Query: 58  DNSWPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPA 117
           DNSWPVA KFMGLGA K+K+  QIV TLDHD+QNKSE NL KY+NI  FAK   ID YPA
Sbjct: 64  DNSWPVATKFMGLGAKKVKDNRQIVNTLDHDVQNKSEANLKKYENIAKFAKLQGIDFYPA 123

Query: 118 GRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIP 177
           GRGIGHQIMIEEGYAFP N+TVASDSHSNTYGG+ SLGTPIVRTDAA+IWATGQTWWQIP
Sbjct: 124 GRGIGHQIMIEEGYAFPGNLTVASDSHSNTYGGVASLGTPIVRTDAASIWATGQTWWQIP 183

Query: 178 PVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMT 237
           PVA+VELKG+L +GV+GKDIIVALCG+FNND+VLNHAIEF GD +  L ID+RLTIANMT
Sbjct: 184 PVAKVELKGKLAKGVTGKDIIVALCGVFNNDEVLNHAIEFVGDGVEQLSIDYRLTIANMT 243

Query: 238 TEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAK 297
           TEWGALSGLFPVD  L+ WY+ RL+++G  +HPRIN KT+  L +     K+D DA YAK
Sbjct: 244 TEWGALSGLFPVDDKLVQWYQQRLERVG-PDHPRINKKTVGELMQ--NQIKSDADAKYAK 300

Query: 298 KLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCP 357
            L+IDL+TL  YVSGPNSVK+SN++  LSQ +I INKAYLVSCTNSRLSD+++AA ++  
Sbjct: 301 HLVIDLSTLAPYVSGPNSVKISNSLTKLSQDNIAINKAYLVSCTNSRLSDIEAAAGIL-- 358

Query: 358 TGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGL 417
                K +KV P VEFYVAAASS ++ DA   GAW+ +L AG  PLP+GCGPCIGLG+GL
Sbjct: 359 -----KGHKVHPNVEFYVAAASSLVQKDAEALGAWQTILDAGAKPLPAGCGPCIGLGSGL 413

Query: 418 LEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGV 477
           L+ GEVGISATNRNFKGRMGSKDALAYLASP VVAASA+LG+I +P EV           
Sbjct: 414 LKDGEVGISATNRNFKGRMGSKDALAYLASPEVVAASAILGRIGAPEEVDGAP----VNA 469

Query: 478 KTEIIENPVVEEE-VNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTY 536
             EI+++  +E+    A  +A   ++++LEGFP+   GEL+LC+ADNINTDGIYPGKYTY
Sbjct: 470 SPEIVKSIEIEDSLAPAADDASSGAIDVLEGFPKSIEGELILCNADNINTDGIYPGKYTY 529

Query: 537 QDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVS 596
           QDD+ KE+MA+VCMENYD EF+TK    DI++SG+NFGTGSSREQAAT +LA+G+ LVV+
Sbjct: 530 QDDISKEQMAEVCMENYDPEFKTKTRSDDIIISGYNFGTGSSREQAATCILARGMKLVVA 589

Query: 597 GSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTE 656
           GSFGNIFSRN+INNALLTLEIP LI KLREKYQG+  ELT RTGWFLKWDV  A V V +
Sbjct: 590 GSFGNIFSRNAINNALLTLEIPDLINKLREKYQGS-NELTIRTGWFLKWDVTTATVTVAD 648

Query: 657 GSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
              D  VIL+QKVGELG NLQ+IIVKGGLEGWVK++L
Sbjct: 649 S--DANVILKQKVGELGTNLQDIIVKGGLEGWVKAEL 683
>ref|XP_359935.2| hypothetical protein MGG_04842 [Magnaporthe grisea 70-15]
 gb|EDJ95590.1| hypothetical protein MGG_04842 [Magnaporthe grisea 70-15]
          Length = 776

 Score =  899 bits (2324), Expect = 0.0,   Method: Composition-based stats.
 Identities = 415/709 (58%), Positives = 498/709 (70%), Gaps = 37/709 (5%)

Query: 20  GQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPS 79
            Q LTEKIVQ Y+V L  GK V SGDYV++ P HCM+HDNSWPVALKFM +GA+KI +  
Sbjct: 68  PQTLTEKIVQRYSVGLAPGKKVKSGDYVTLSPHHCMTHDNSWPVALKFMSIGASKIHDNR 127

Query: 80  QIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTV 139
           Q+V TLDHD+QNKSE NL KY+ IE FAK H +D YPAGRGIGHQIM+EEGYA+P  +TV
Sbjct: 128 QVVMTLDHDVQNKSESNLKKYRQIEEFAKTHGVDFYPAGRGIGHQIMVEEGYAWPGTVTV 187

Query: 140 ASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIV 199
           ASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V L G LP GV+GKD+IV
Sbjct: 188 ASDSHSNMYGGVGCLGTPMVRTDAASIWATGKTWWQIPPIAKVTLTGVLPPGVTGKDVIV 247

Query: 200 ALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWY 257
           ALCGLFNND+VLNHAIEFTG  +++ ++P+D RL IANMTTEWGAL+GLFP+D  L  W 
Sbjct: 248 ALCGLFNNDEVLNHAIEFTGSEETMRSIPVDDRLAIANMTTEWGALAGLFPIDSVLQGWL 307

Query: 258 KNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
           + +          R      +  E      +AD  A YAK L ++L+TL  +V+GPNSVK
Sbjct: 308 RGKATTSAMFGGGRDVFTHEKIEELIQNQLRADPGAKYAKSLYLNLSTLAPFVAGPNSVK 367

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAA 377
           V+  ++DL  +DIK+NKAYLVSCTNSR SD+ +AA V        K   +APGV+FY+ A
Sbjct: 368 VATPLKDLEAKDIKVNKAYLVSCTNSRASDIAAAAKVFKEASKDGKPAVIAPGVKFYIGA 427

Query: 378 ASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMG 437
           AS+  +A A ++G W+ LL AG   LP+GCGPCIGLG GLLEPGEVGISA+NRNFKGRMG
Sbjct: 428 ASTLEQAAAEEAGDWKVLLDAGAQALPAGCGPCIGLGTGLLEPGEVGISASNRNFKGRMG 487

Query: 438 SKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPF----SGVKTEIIENPVVEEEVNA 493
           S DA AYLAS  VVAASA+ GKI+ P        +       G    + +  V  EE  A
Sbjct: 488 STDAKAYLASQEVVAASALKGKIAGPGWYEKPEGVEKVIIGEGNGDAVHDKAVSIEEALA 547

Query: 494 QTEAPKQS------------------------VEILEGFPREFSGELVLCDADNINTDGI 529
           +     +S                         EIL GFP    GE+V CDADNINTDGI
Sbjct: 548 KLLGEAESMISDAEQNLGGSSQQAESAEEETLTEILPGFPERVEGEIVFCDADNINTDGI 607

Query: 530 YPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAK 589
           YPGKYTYQD+V  EKMA+VCMENYD EF      GD++V+GFNFG GSSREQAATA+LAK
Sbjct: 608 YPGKYTYQDNVSTEKMAEVCMENYDKEFGKVAREGDVLVAGFNFGCGSSREQAATAILAK 667

Query: 590 GINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGA-----PKELTRRTGWFLK 644
            I LVV+GSFGNIFSRNSINNAL+ +E+P L+++LRE + G       K LTRRTGW   
Sbjct: 668 RIPLVVAGSFGNIFSRNSINNALMGVEVPRLVERLRETFGGKEQGEENKALTRRTGWTFV 727

Query: 645 WDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           WDV  +KV VTEGS  G     QKVGEL  N+QEII +GGLE WVKSQ+
Sbjct: 728 WDVRRSKVTVTEGS--GGETWSQKVGELPPNVQEIIARGGLEKWVKSQI 774
>ref|XP_001822935.1| hypothetical protein [Aspergillus oryzae RIB40]
 sp|Q2U9G3|LYS4_ASPOR Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 dbj|BAE61802.1| unnamed protein product [Aspergillus oryzae]
          Length = 775

 Score =  897 bits (2319), Expect = 0.0,   Method: Composition-based stats.
 Identities = 419/729 (57%), Positives = 502/729 (68%), Gaps = 43/729 (5%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S     S  +SRA    Q LTEKIVQ Y+V L + K V SGDYV+I P  CM+HDNSWPV
Sbjct: 49  SAAVYSSLQASRAV--PQTLTEKIVQKYSVGLAKDKFVKSGDYVTISPHRCMTHDNSWPV 106

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GATK+ +P QIV TLDHD+QNKSEKNL KY+ IE+FAK   ++ YPAGRGIGH
Sbjct: 107 ALKFMSIGATKLHDPKQIVMTLDHDVQNKSEKNLQKYRQIEDFAKHQGVEFYPAGRGIGH 166

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           Q+M+EEGYA+P  + VASDSHSN YGG+G LGTPIVRTD A+IWATG+TWWQIPPVA+V 
Sbjct: 167 QVMVEEGYAWPGTLVVASDSHSNMYGGVGCLGTPIVRTDGASIWATGKTWWQIPPVAKVT 226

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
           L G LP GV+GKD+IVALCGLF+ D VLNHAIEFTG  +++ +L +D RLTIANMTTEWG
Sbjct: 227 LTGVLPPGVTGKDVIVALCGLFDKDDVLNHAIEFTGPEETMRSLSVDARLTIANMTTEWG 286

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNH-------PRINPKTIRALEEKAKIPKADKDAH 294
           ALSGLFP+D  L  W K +                   +       +  A    ADK A 
Sbjct: 287 ALSGLFPIDNVLKGWLKGKATTAAMGLAEGPFKTLAPQHFTHPLLEQLFANPLTADKGAK 346

Query: 295 YAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADV 354
           YAK+L +DL+TL+ YVSGPNSVKV+  ++DL  Q+IK+NKAYLVSCTNSR SD+ +AA V
Sbjct: 347 YAKELFLDLSTLSPYVSGPNSVKVATPLKDLEAQNIKVNKAYLVSCTNSRASDIAAAARV 406

Query: 355 VCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIG 412
                + N     K+A GVEFYVAAAS   +  A ++G W+ LL AG  PL  GC  CIG
Sbjct: 407 FKEAAEKNGGKVPKIADGVEFYVAAASIPEQLAAEEAGDWQALLDAGATPLLPGCAQCIG 466

Query: 413 LGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEI 472
           LG GLLE GEVGISA+NRNFKGRMGS DA AYL SP VVAASA+ GK+S P    +   +
Sbjct: 467 LGTGLLEAGEVGISASNRNFKGRMGSTDAKAYLGSPEVVAASALTGKLSGPGWYQAPEGL 526

Query: 473 ------PFSGVKTE---------------IIENPVVEEEVNAQTEAPK-----QSVEILE 506
                    G++ E                I+N V + E     E  +        E+  
Sbjct: 527 TEVVRGEGDGIREEDRMLTAEQALEKLIGQIDNLVADGEKQFAPEESEESSGDSLTEVYP 586

Query: 507 GFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDI 566
           GFP   SGE+V CDADNINTDGIYPGKYTYQDDV +E MAQVCM NYDA+F +    GDI
Sbjct: 587 GFPERVSGEIVFCDADNINTDGIYPGKYTYQDDVSQETMAQVCMSNYDAQFSSIAKEGDI 646

Query: 567 VVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLRE 626
           +V+GFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P LI +LRE
Sbjct: 647 LVTGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLINRLRE 706

Query: 627 KY--QGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGG 684
            +  +G+ K LTRRTGW L WDV  +++ V EG  +       +VGEL  N+QEII KGG
Sbjct: 707 SFSGEGSDKSLTRRTGWTLTWDVRRSRIEVQEG--ENGPKWTHQVGELPPNVQEIIAKGG 764

Query: 685 LEGWVKSQL 693
           LE WVK+++
Sbjct: 765 LEKWVKNEI 773
>ref|XP_001396574.1| hypothetical protein An15g00350 [Aspergillus niger]
 sp|Q58FL6|LYS4_ASPNC Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|AAX53108.1| homoaconitate hydratase [Aspergillus niger]
 emb|CAK42204.1| unnamed protein product [Aspergillus niger]
          Length = 769

 Score =  897 bits (2318), Expect = 0.0,   Method: Composition-based stats.
 Identities = 409/726 (56%), Positives = 501/726 (69%), Gaps = 42/726 (5%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S     S  SSRA    Q LTEKIVQ YAV LP+GK V SGDYV+I P   M+HDNSWPV
Sbjct: 48  SAALFSSLQSSRAV--PQTLTEKIVQKYAVGLPDGKFVKSGDYVTIAPHRIMTHDNSWPV 105

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GA+K+ +P+Q+V TLDHD+QNK+EKNL KY+ IE FAK+H ++ YPAGRGIGH
Sbjct: 106 ALKFMSIGASKMHDPNQVVMTLDHDVQNKTEKNLQKYRQIEEFAKQHGVEFYPAGRGIGH 165

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEG+A+P  + VASDSHSNTYG + S+GTPIVRTDAA+IWATG+TWWQIPPVA+V 
Sbjct: 166 QIMVEEGFAWPGTLVVASDSHSNTYGAVASVGTPIVRTDAASIWATGKTWWQIPPVAKVT 225

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
             G LP GV+GKD+IVALCGLF+ D VLNHAIEFTG  +++ +LP+D RLTIANMTTEWG
Sbjct: 226 FTGILPPGVTGKDVIVALCGLFDKDDVLNHAIEFTGSEETMRSLPMDSRLTIANMTTEWG 285

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNH-------PRINPKTIRALEEKAKIPKADKDAH 294
           ALSGLFP+D  L  W K +                   N       +       ADK A 
Sbjct: 286 ALSGLFPMDGVLKGWLKGKATTAAMGLADGPFKTLAARNFTHPAIEQLFVNPLTADKGAK 345

Query: 295 YAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADV 354
           YAK+L +DL+TL+ YVSGPNSVK++  +++L  QDIK++KAYLVSCTNSR SD+ +AA V
Sbjct: 346 YAKELFLDLSTLSPYVSGPNSVKIATPLKELEAQDIKVDKAYLVSCTNSRASDIAAAAKV 405

Query: 355 VCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIG 412
                + N     K+A GV+FY+AAAS   +  A  +G W+ LL+AG   LP+GCGPCIG
Sbjct: 406 FKDAAEKNGGKVPKIADGVKFYIAAASIPEQLAAEGAGDWQTLLEAGATALPAGCGPCIG 465

Query: 413 LGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEI 472
           LG GLLEPGEVGISA+NRNFKGRMGS +A AYL SP +VAASA+ GK+S P         
Sbjct: 466 LGTGLLEPGEVGISASNRNFKGRMGSTEAKAYLGSPEIVAASALSGKLSGPGWYQPPEGW 525

Query: 473 ------PFSGVKTE---------------IIENPVVEEEV----NAQTEAPKQSVEILEG 507
                    G++ E                +++ V + E       + E      E+  G
Sbjct: 526 TEVVRGEGDGIREEDRMLNTEQALEKLLGQLDDLVADGEKRFAPEEKVEEEGGLTEVYPG 585

Query: 508 FPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIV 567
           FP   SGE+V CDADN+NTD IYPG +TYQD+VP EKMA+VCM NYD EF +    GDI+
Sbjct: 586 FPERVSGEIVFCDADNLNTDAIYPGYWTYQDNVPVEKMAEVCMSNYDKEFASIAKEGDIL 645

Query: 568 VSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREK 627
           V G+NFG GSSREQAATALLAK I LVVSGSFGNIFSRNSINNAL+ LE+P L+ +LRE+
Sbjct: 646 VVGYNFGCGSSREQAATALLAKQIPLVVSGSFGNIFSRNSINNALMGLEVPRLVSRLREE 705

Query: 628 YQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEG 687
           +    K+LTRRTGW L WDV  +++ + EG          KVGEL  N+QEII KGGLE 
Sbjct: 706 F--GDKQLTRRTGWTLTWDVRRSQIEIQEGQN--GPKWTHKVGELPPNVQEIIAKGGLEK 761

Query: 688 WVKSQL 693
           WVK+ +
Sbjct: 762 WVKNAI 767
>ref|XP_001911427.1| unnamed protein product [Podospora anserina]
 emb|CAP73252.1| unnamed protein product [Podospora anserina]
          Length = 781

 Score =  896 bits (2317), Expect = 0.0,   Method: Composition-based stats.
 Identities = 421/720 (58%), Positives = 505/720 (70%), Gaps = 39/720 (5%)

Query: 11  FHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGL 70
             +  A    Q LTEKIVQ Y+V L  GK V SGDYV++ P HCM+HDNSWPVA+KFM +
Sbjct: 62  PSAKSATQTPQTLTEKIVQRYSVGLAPGKTVKSGDYVTLAPHHCMTHDNSWPVAMKFMSI 121

Query: 71  GATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEG 130
           GA+KI +  Q+V TLDHD+QNKSE NL KY+ IE FA KH +D YPAGRGIGHQIM+EEG
Sbjct: 122 GASKIHDNRQVVMTLDHDVQNKSEANLKKYRQIEEFAGKHGVDFYPAGRGIGHQIMVEEG 181

Query: 131 YAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQ 190
           YA+P  +TVASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V L G LP 
Sbjct: 182 YAWPGTVTVASDSHSNMYGGVGCLGTPMVRTDAASIWATGRTWWQIPPIAKVTLTGILPP 241

Query: 191 GVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFP 248
           GV+GKD+IVALCGLFNND VLNHAIEFTG  +++ +L ID RL IANMTTEWGALSGLFP
Sbjct: 242 GVTGKDVIVALCGLFNNDDVLNHAIEFTGSEETMRSLSIDDRLAIANMTTEWGALSGLFP 301

Query: 249 VDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEK--AKIPKADKDAHYAKKLIIDLATL 306
           +D  L  W + +       N      K      +       +AD  A YAK L ++L+TL
Sbjct: 302 IDSVLQQWLRAKATTAAMFNPEAAKGKFTHEKIDDLINNQLRADPGATYAKSLYLNLSTL 361

Query: 307 THYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNK 366
           + +V+GPNSVKV+  ++DL  QDIK+NKAYLVSCTNSR SD+ +AA+V         + K
Sbjct: 362 SPFVAGPNSVKVATPLKDLEAQDIKLNKAYLVSCTNSRASDIAAAANVFREVAKDGVIPK 421

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           VA GV+FY+AAAS+  +A A ++G W+ LL AG  PLPSGCGPCIGLG GLLEPGEVGIS
Sbjct: 422 VAEGVKFYIAAASTLEQAAAEEAGDWQVLLAAGAEPLPSGCGPCIGLGTGLLEPGEVGIS 481

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPF------------ 474
           A+NRNFKGRMGS DA AYLASP VVAASA+ GKI+ P        +              
Sbjct: 482 ASNRNFKGRMGSTDAKAYLASPEVVAASALKGKIAGPGWYQKPEGVEKVIIGEGNGDVVQ 541

Query: 475 -SGVKTEIIENPVVEEEVNAQTEAPKQ-----------------SVEILEGFPREFSGEL 516
              +  E   + ++ +  +    A K+                   EIL GFP +  GE+
Sbjct: 542 DKAMSIEEALDKLIAQADSMIASAEKEFSGDEAAAAESAAEAETLTEILPGFPEKIEGEI 601

Query: 517 VLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTG 576
           V CDADNINTDGIYPGKYTYQD+V  EKMA+VCMENYD EF      GDI+VSGFNFG G
Sbjct: 602 VFCDADNINTDGIYPGKYTYQDNVTTEKMAEVCMENYDKEFGQVAKEGDILVSGFNFGCG 661

Query: 577 SSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQG---APK 633
           SSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ +E+P L+++LRE ++      K
Sbjct: 662 SSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGVEVPRLVQRLRETFKADGEGNK 721

Query: 634 ELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            LTRRTGW L WDV  +KV VTEG  +G     QKVGEL  N+QEII +GGLE WVKSQ+
Sbjct: 722 VLTRRTGWKLVWDVRRSKVTVTEG--EGGQQWSQKVGELPPNVQEIIARGGLEKWVKSQI 779
>ref|XP_001248868.1| hypothetical protein CIMG_02639 [Coccidioides immitis RS]
 gb|EAS37285.1| hypothetical protein CIMG_02639 [Coccidioides immitis RS]
          Length = 801

 Score =  894 bits (2312), Expect = 0.0,   Method: Composition-based stats.
 Identities = 415/727 (57%), Positives = 510/727 (70%), Gaps = 41/727 (5%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           +     +  SS+A    Q LTEKIVQ Y+V LP+ K V SGDYV+I P   M+HDNSWPV
Sbjct: 77  AAAILSAMESSKAV--PQTLTEKIVQRYSVGLPKDKYVKSGDYVTISPHRVMTHDNSWPV 134

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GA+K+ +P+QIV TLDHD+QNKSEKNL KY+ IE FAK H +D YPAGRGIGH
Sbjct: 135 ALKFMSIGASKLNDPNQIVMTLDHDVQNKSEKNLKKYEQIETFAKTHGVDFYPAGRGIGH 194

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEGYA+P  + VASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V 
Sbjct: 195 QIMVEEGYAWPGTLVVASDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVT 254

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
            +G LP+GV+GKD+IVALCGLF+ D VLNHAIEFTG  +++ ++ ID RLTIANMTTEWG
Sbjct: 255 FRGVLPKGVTGKDVIVALCGLFDKDDVLNHAIEFTGSEETMRSIHIDDRLTIANMTTEWG 314

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKA--------KIPKADKDA 293
           ALSGLFPVD  L  W +++              ++  A   K         +   ADK A
Sbjct: 315 ALSGLFPVDSMLKGWLRSKATTAAMWGSTVPELQSSAAERFKHAALDQLFEEPLVADKGA 374

Query: 294 HYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAAD 353
            YAK+L +DL+TL+ YV+GPNSVKV+  +++L  Q+IK+NKAYLVSCTNSR SD+ +AA 
Sbjct: 375 KYAKELFLDLSTLSPYVAGPNSVKVATPLKELESQNIKVNKAYLVSCTNSRASDIAAAAK 434

Query: 354 VVCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCI 411
           V     + N     K+A GV+FY+AAAS   +  A ++G W+ LL+AG  PLP+GCGPCI
Sbjct: 435 VFKEAAEKNGGKIPKIADGVKFYIAAASIPEQRAAEEAGDWQALLEAGAEPLPAGCGPCI 494

Query: 412 GLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSE 471
           GLG GLLEPGEVGISATNRNFKGRMGS +A AYL+SP VVAASA+ G IS P        
Sbjct: 495 GLGTGLLEPGEVGISATNRNFKGRMGSTEAKAYLSSPEVVAASALSGTISGPGWYEKPEG 554

Query: 472 ----IPFSGVKTEIIENPVVEEEVNAQTEAPKQS------------------VEILEGFP 509
               +   G   E+I      E+V  Q ++  +                    E+  GFP
Sbjct: 555 WTGVVRGEGDGNEMITAEQALEKVIGQLDSMVEDAEKLFASEESNSSGEEGLTEVYPGFP 614

Query: 510 REFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVS 569
              SGE+V CDADNINTDGIYPGKYTYQD++P E+M + CMENYD +F      GDI+V+
Sbjct: 615 ERVSGEIVFCDADNINTDGIYPGKYTYQDNIPYEQMGEYCMENYDTQFGKVAKAGDILVT 674

Query: 570 GFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKY- 628
           G+NFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P LI +LRE + 
Sbjct: 675 GYNFGCGSSREQAATAILAKQIPLVVSGSFGNIFSRNSINNALMGLEVPRLITRLRETFG 734

Query: 629 --QGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLE 686
             +   K+LTRRTGW L WDV  +++ + EG  DGP    QKVGEL  N+QEII  GGLE
Sbjct: 735 SDKTDSKQLTRRTGWTLTWDVRRSQIEIQEGP-DGPK-WTQKVGELPPNVQEIIALGGLE 792

Query: 687 GWVKSQL 693
            WVK+ +
Sbjct: 793 KWVKNSI 799
>ref|XP_001539249.1| homoaconitase, mitochondrial precursor [Ajellomyces capsulatus
           NAm1]
 gb|EDN09687.1| homoaconitase, mitochondrial precursor [Ajellomyces capsulatus
           NAm1]
          Length = 797

 Score =  880 bits (2275), Expect = 0.0,   Method: Composition-based stats.
 Identities = 412/741 (55%), Positives = 501/741 (67%), Gaps = 64/741 (8%)

Query: 13  SSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGA 72
            S    + Q L EKIVQ Y+V L  GK V SGDYV+I P  CM+HDNSWPVALKFM +GA
Sbjct: 58  ESATAPEPQTLVEKIVQKYSVGLAPGKKVRSGDYVTISPYKCMTHDNSWPVALKFMSIGA 117

Query: 73  TKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYA 132
           +K+++  QIV TLDHD+QNKSEKNL KY+ IE FAK H +D YPAGRGIGHQIM+EEGYA
Sbjct: 118 SKLQDRKQIVMTLDHDVQNKSEKNLLKYQQIEQFAKTHGVDFYPAGRGIGHQIMVEEGYA 177

Query: 133 FPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGV 192
           +P  + VASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V   G LP+GV
Sbjct: 178 WPGTLVVASDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVNFTGVLPKGV 237

Query: 193 SGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVD 250
           +GKD+IVALCGLF+ D VLNHAIEFTG  +++ +L ID RLTIANMTTEWGAL+G+FPVD
Sbjct: 238 TGKDVIVALCGLFDKDDVLNHAIEFTGSEETMRSLAIDDRLTIANMTTEWGALAGIFPVD 297

Query: 251 KTLIDWYKNRLQKLG----------TNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
             L  W +++               ++ + R     +  + E  +   ADK A Y+K+L 
Sbjct: 298 NILKGWLRSKATAAAMWVSSVNGLPSSANTRFTHSQLDKVLE--RPLAADKGAKYSKELS 355

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           +DL+TL  YVSGPNSVKV+  +  L  QDIK+NKAYLVSCTNSR SDL +AA V     +
Sbjct: 356 LDLSTLAPYVSGPNSVKVATPLDKLEAQDIKVNKAYLVSCTNSRASDLAAAAKVFRQAAE 415

Query: 361 LNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLL 418
            N     K+A GV+FY+AAAS   +  A ++G W+ L++AG  PLP+GCGPCIGLG GLL
Sbjct: 416 KNDGKIPKLADGVKFYIAAASIPEQNAAEEAGDWQVLVEAGAQPLPAGCGPCIGLGTGLL 475

Query: 419 EPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEI------ 472
           EPGEVGISATNRNFKGRMGS +A AYLASP VVAASA+ G IS P               
Sbjct: 476 EPGEVGISATNRNFKGRMGSTEAKAYLASPEVVAASALRGTISGPGWYEKPEGWAGVSRG 535

Query: 473 PFSGVKTE---------------IIENPVVEEEVNAQTEA-------------------- 497
              G+K E                ++N V + E     EA                    
Sbjct: 536 EGVGIKEEDRMLTAEEAIANVIGQLDNMVEDAEKIYGNEAISSTSTSQPSQQSKQQEEPG 595

Query: 498 --PKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDA 555
                  E+  GFP   SGE++ CDADNINTDGIYPGKYTYQD++  ++MAQVCM NYDA
Sbjct: 596 TDSSALTELFPGFPECVSGEIIFCDADNINTDGIYPGKYTYQDNISTDQMAQVCMSNYDA 655

Query: 556 EFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTL 615
            F      GDI+V+G+NFG GSSREQAATA+LAK I LVV+GSFGNIFSRNSINNAL+ L
Sbjct: 656 AFSQLTRAGDILVTGYNFGCGSSREQAATAILAKRIPLVVAGSFGNIFSRNSINNALMGL 715

Query: 616 EIPALIKKLREKYQ---GAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGEL 672
           E+P LI++LRE +       K LTRRTGW L WDV  +++ V EG  +G      KVGEL
Sbjct: 716 EVPRLIQRLRESFSSTGAGKKALTRRTGWTLTWDVRRSRIEVQEG--EGGEKWTHKVGEL 773

Query: 673 GKNLQEIIVKGGLEGWVKSQL 693
             N+QEII +GGLE WVK+ +
Sbjct: 774 PPNVQEIIARGGLEKWVKNAI 794
>gb|EEH41326.1| homoaconitase [Paracoccidioides brasiliensis Pb01]
          Length = 809

 Score =  878 bits (2270), Expect = 0.0,   Method: Composition-based stats.
 Identities = 413/745 (55%), Positives = 500/745 (67%), Gaps = 60/745 (8%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S   +    S+ A    Q L EKIVQ ++V LP+GK V SGDYV+I P  CM+HDNSWPV
Sbjct: 67  SAILSSIESSTAATPVPQTLVEKIVQRFSVGLPQGKYVRSGDYVTISPYKCMTHDNSWPV 126

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GA+K+++P Q+V TLDHD+QN+SEKNL KY+ IE FAK H +D YPAGRGIGH
Sbjct: 127 ALKFMSIGASKLQDPKQVVMTLDHDVQNRSEKNLQKYRQIEQFAKTHEVDFYPAGRGIGH 186

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEGYA+P  + VASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V 
Sbjct: 187 QIMVEEGYAWPGTLVVASDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVT 246

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWG 241
             G LP+GV+GKD+IVALCGLF+ D VLNHAIEF G   ++ +L ID RLTIANMTTEWG
Sbjct: 247 FTGVLPKGVTGKDVIVALCGLFDKDDVLNHAIEFAGSEATMRSLAIDDRLTIANMTTEWG 306

Query: 242 ALSGLFPVDKTLIDWYKNRLQKL--------GTNNHPRINPKTIRALEEKAKIPKADKDA 293
           AL+GLFPVD  L  W +++            G  +            +   +   ADK A
Sbjct: 307 ALAGLFPVDSVLKGWLRSKATTAAMWGSSVDGLPSSANTRFTHPLLDKMFEQPLAADKGA 366

Query: 294 HYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAAD 353
            YAK+L +DL+TL  YVSGPNSVKV++ + +L  QDIK+NKAYLVSCTNSR SDL +AA 
Sbjct: 367 QYAKELYLDLSTLPPYVSGPNSVKVASPLNELEAQDIKVNKAYLVSCTNSRASDLAAAAK 426

Query: 354 VVCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCI 411
           V       N     K+A GV+FY+AAAS   +  A ++G W+ L++AG  PLP+GCGPCI
Sbjct: 427 VFKEAAAKNNGKIPKLADGVKFYIAAASIPEQKAAEEAGDWQTLIEAGAEPLPAGCGPCI 486

Query: 412 GLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTS- 470
           GLG GLLEPGEVGISATNRNFKGRMGS DA AYLASP VVAASA+ GKIS P        
Sbjct: 487 GLGTGLLEPGEVGISATNRNFKGRMGSTDAKAYLASPEVVAASALSGKISGPGWYEKPES 546

Query: 471 -----EIPFSGVKTEIIENPVVEEEVNAQTEAPKQS------------------------ 501
                     GVK E  +  +  EE   +      +                        
Sbjct: 547 WTGVVRGEGDGVKEE--DRMLTAEEAIEKVINQLDNMVEDAEKIFGNESSSSSTSATASP 604

Query: 502 -------------VEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQV 548
                         E+   FP   SGE++ CDADNINTDGIYPGKYTYQD+V + +MA V
Sbjct: 605 QQSKNSSDNSSSLTEVYPDFPSRVSGEIIFCDADNINTDGIYPGKYTYQDNVTRTQMAAV 664

Query: 549 CMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSI 608
           CM NYDA F T   PGDI+V+GFNFG GSSREQAATA+LAK I LVV+GSFGNIFSRNSI
Sbjct: 665 CMSNYDASFSTLARPGDILVTGFNFGCGSSREQAATAILAKDIPLVVAGSFGNIFSRNSI 724

Query: 609 NNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQK 668
           NNAL+ LE+P L+ +LRE + G  K LT+RTGW L WDV  + + V EG  +G      +
Sbjct: 725 NNALMGLEVPRLVSRLREVFGGQGK-LTQRTGWKLTWDVRRSLIEVQEG--EGGPKWTHR 781

Query: 669 VGELGKNLQEIIVKGGLEGWVKSQL 693
           VGEL  N+QEII +GGLE WVK+ +
Sbjct: 782 VGELPPNVQEIIARGGLEKWVKNAI 806
>gb|EEH50136.1| homoaconitase [Paracoccidioides brasiliensis Pb18]
          Length = 857

 Score =  878 bits (2269), Expect = 0.0,   Method: Composition-based stats.
 Identities = 415/745 (55%), Positives = 498/745 (66%), Gaps = 58/745 (7%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S   +    S+ A    Q L EKIVQ YAV LP GK V SGDYV+I P  CM+HDNSWPV
Sbjct: 113 SAILSSIESSTAAAPVPQTLVEKIVQRYAVGLPPGKYVRSGDYVTISPYKCMTHDNSWPV 172

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GA+K+++P Q+V TLDHD+QNKSEKNL KY+ IE FAK H +D YPAGRGIGH
Sbjct: 173 ALKFMSIGASKLQDPKQVVMTLDHDVQNKSEKNLHKYRQIEQFAKTHEVDFYPAGRGIGH 232

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEGYA+P  + VASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V 
Sbjct: 233 QIMVEEGYAWPGTLVVASDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVT 292

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWG 241
             G LP+GV+GKD+IVALCGLF+ D VLNHAIEF G   +L +L I+ RLTIANMTTEWG
Sbjct: 293 FTGVLPRGVTGKDVIVALCGLFDKDDVLNHAIEFAGSEATLRSLAIEDRLTIANMTTEWG 352

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIP--------KADKDA 293
           AL+GLFPVD  L  W +++               +         +          ADK A
Sbjct: 353 ALAGLFPVDSVLKGWLRSKATTAAMWGSSVDGLPSSANTRFTHPLLDKMFEQPMAADKGA 412

Query: 294 HYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAAD 353
            YAK+L +DL+TL  YVSGPNSVKV+  + +L  QDIK+NKAYLVSCTNSR SDL +AA 
Sbjct: 413 QYAKELYLDLSTLPPYVSGPNSVKVARPLNELEAQDIKVNKAYLVSCTNSRASDLAAAAK 472

Query: 354 VVCPTGDLNKV--NKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCI 411
           V       N     K+A GV+FY+AAAS   +  A ++G W+ L++AG  PLP+GCGPCI
Sbjct: 473 VFKEAAAKNDGSIPKLADGVKFYIAAASIPEQKAAEEAGDWQTLIEAGAEPLPAGCGPCI 532

Query: 412 GLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTS- 470
           GLG GLLEPGEVGISATNRNFKGRMGS DA AYLASP VVAASA+ GKIS P        
Sbjct: 533 GLGTGLLEPGEVGISATNRNFKGRMGSTDAKAYLASPEVVAASALSGKISGPGWYEKPES 592

Query: 471 -----EIPFSGVKTE---------------IIENPVVEEEVN------------------ 492
                     G+K E                ++N V + E                    
Sbjct: 593 WTGVVRGEGDGIKEEDRMLTAEEAIEKVINQLDNMVEDAEKIFGNASSSSSTSATASPQP 652

Query: 493 ----AQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQV 548
                 ++      E+  GFP   SGE++ CDADNINTDGIYPGKYTYQD+V + +MA V
Sbjct: 653 QQSKDSSDNCASLTEVYPGFPSRVSGEIIFCDADNINTDGIYPGKYTYQDNVSRTQMAAV 712

Query: 549 CMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSI 608
           CM NYDA F T   PGDI+ +GFNFG GSSREQAATA+LAK I LVV+GSFGNIFSRNSI
Sbjct: 713 CMSNYDASFSTLARPGDILATGFNFGCGSSREQAATAILAKDIPLVVAGSFGNIFSRNSI 772

Query: 609 NNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQK 668
           NNAL+ LE+P L+ +LRE + G  K LT+RTGW L WDV  + + V EG  +G      +
Sbjct: 773 NNALMGLEVPRLVSRLREVFGGQGK-LTQRTGWKLTWDVRRSLIEVQEG--EGGPKWTHR 829

Query: 669 VGELGKNLQEIIVKGGLEGWVKSQL 693
           VGEL  N+QEII +GGLE WVK+ +
Sbjct: 830 VGELPPNVQEIIARGGLEKWVKNAI 854
>ref|XP_958836.1| homoaconitase, mitochondrial precursor [Neurospora crassa OR74A]
 sp|Q870W1|LYS4_NEUCR Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|EAA29600.1| homoaconitase, mitochondrial precursor [Neurospora crassa OR74A]
 emb|CAD71225.1| probable homoaconitase precursor [Neurospora crassa]
          Length = 784

 Score =  876 bits (2265), Expect = 0.0,   Method: Composition-based stats.
 Identities = 415/729 (56%), Positives = 504/729 (69%), Gaps = 45/729 (6%)

Query: 5   TTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA 64
                S          Q LTEKIVQ Y+V L  GK V SGDYV+++P HCM+HDNSWPVA
Sbjct: 59  ENLASSTLPKVVPQVPQTLTEKIVQRYSVGLAPGKKVKSGDYVTLQPHHCMTHDNSWPVA 118

Query: 65  LKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQ 124
           +KFM +GA+KI +  Q+V TLDHD+QNKSE NL KY+ IE FA  H +D YPAGRGIGHQ
Sbjct: 119 MKFMSIGASKIHDNRQVVMTLDHDVQNKSEANLKKYRQIEEFANTHGVDFYPAGRGIGHQ 178

Query: 125 IMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVEL 184
           IM+EEGYA+P  +TVASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V  
Sbjct: 179 IMVEEGYAWPGTVTVASDSHSNMYGGVGCLGTPMVRTDAASIWATGKTWWQIPPIAKVTF 238

Query: 185 KGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGA 242
            G LP GV+GKD+IVALCGLFNND VLNHAIEFTG  +++ ++P+D RLTIANMTTEWGA
Sbjct: 239 TGLLPPGVTGKDVIVALCGLFNNDDVLNHAIEFTGAEETMRSIPVDDRLTIANMTTEWGA 298

Query: 243 LSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKI---PKADKDAHYAKKL 299
           LSGLFP+D  L  W + +       +    +       +  A +     AD  A YAK+L
Sbjct: 299 LSGLFPIDAVLASWMRAKATVTAMEHPELGDKAKFTHAKIDALLENPLVADPGATYAKQL 358

Query: 300 IIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTG 359
            ++L+TL+ +V+GPNSVK++  ++DL  Q++K++KAYLVSCTNSR SD+ +AA V     
Sbjct: 359 YLNLSTLSPFVAGPNSVKIATPLKDLEAQNLKLDKAYLVSCTNSRASDIAAAARVFKDAA 418

Query: 360 DLNKV--NKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGL 417
             N     KVAPGV+FY+AAAS   +  A  SG W+ LL AG  PLPSGCGPCIGLG GL
Sbjct: 419 ADNNGVIPKVAPGVKFYIAAASLLEQKQAEDSGDWQVLLDAGAEPLPSGCGPCIGLGTGL 478

Query: 418 LEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGV 477
           LEPGE+GISA+NRNFKGRMGS DA AYLASP VVAASA+ GKI+ P        +    +
Sbjct: 479 LEPGEIGISASNRNFKGRMGSTDAKAYLASPEVVAASALKGKIAGPGWYQKPEGVEKVII 538

Query: 478 ----------KTEIIENPVVE-----EEVNAQTEAPKQS------------------VEI 504
                     K   IE+ + +     E + A  EA                       EI
Sbjct: 539 GEGNGVVEQDKAMSIEDALDKIIAEAESLIANAEAGLTPESTSSSSSSSSSSEEESLTEI 598

Query: 505 LEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPG 564
           L GFP   SGE++ CDADNINTDGIYPGKYTYQD++   KMA+VCMENYDA F +    G
Sbjct: 599 LPGFPEAISGEIIFCDADNINTDGIYPGKYTYQDNITPAKMAEVCMENYDASFGSIARAG 658

Query: 565 DIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKL 624
           DI+V+GFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ +E+P L+++L
Sbjct: 659 DILVTGFNFGCGSSREQAATAILAKQIPLVVSGSFGNIFSRNSINNALMGVEVPKLVQRL 718

Query: 625 REKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGG 684
           RE++    K  TRRTGW L WDV  +KVVV E S       EQKVGEL  N+QEII +GG
Sbjct: 719 REEF--GDKVATRRTGWKLTWDVRRSKVVVEEAS---GKKWEQKVGELPPNVQEIIARGG 773

Query: 685 LEGWVKSQL 693
           LE WVKSQ+
Sbjct: 774 LEKWVKSQI 782
>gb|ABY84678.1| homoaconitase [Penicillium chrysogenum]
          Length = 785

 Score =  872 bits (2253), Expect = 0.0,   Method: Composition-based stats.
 Identities = 413/709 (58%), Positives = 502/709 (70%), Gaps = 29/709 (4%)

Query: 11  FHSSRAWLK-GQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMG 69
           F  + +  +  Q LTEKIVQ YAV LPEGK+V SGDY+S+ P +CM+HDNSWPVALKFM 
Sbjct: 76  FSETPSEKRTPQTLTEKIVQRYAVGLPEGKLVRSGDYISLAPGYCMTHDNSWPVALKFMS 135

Query: 70  LGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEE 129
           +GATKI  P QIV TLDHD+QN S  NL KY+ IE FA +H ID YPAGRGIGHQ+M+EE
Sbjct: 136 MGATKIHRPEQIVMTLDHDVQNTSAANLKKYEQIETFAGQHGIDFYPAGRGIGHQVMVEE 195

Query: 130 GYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLP 189
           GYA+P  M VASDSHSN YGG+G LGT +VRTDAA+IWAT +TWWQIPPVA+V   G LP
Sbjct: 196 GYAWPGTMAVASDSHSNHYGGVGCLGTAVVRTDAASIWATSRTWWQIPPVARVTFTGTLP 255

Query: 190 QGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLF 247
            GV+GKD+IVALCGLFN+D VLNHAIEFTG  +++ +L +D RLTIANMTTEWGAL+GLF
Sbjct: 256 AGVTGKDVIVALCGLFNSD-VLNHAIEFTGSEETMESLLVDSRLTIANMTTEWGALTGLF 314

Query: 248 PVDKTLIDWYKNRL--QKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLAT 305
           P+D+TL  W + +     +  +   R      R  E  A    AD DA YAK+L ++L+T
Sbjct: 315 PIDRTLKRWLRYKATEAAMSEDRTTRQRITHERIDELFANPLTADPDAQYAKQLYLNLST 374

Query: 306 LTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKV- 364
           L+ YVSGPNSVKV+  + +L+QQ+IK+N+AY+VSCTNSR SDL +AA V       N   
Sbjct: 375 LSPYVSGPNSVKVATPLNELAQQNIKVNRAYIVSCTNSRASDLAAAAKVFKDAAKANPGT 434

Query: 365 -NKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEV 423
             K+A GV+ Y+AAAS+  +  A  +G W+ LL AG  PLP+GCGPCIGLG GLLEPGEV
Sbjct: 435 TPKIADGVKLYIAAASAPEQEAAESTGDWQALLDAGAQPLPAGCGPCIGLGTGLLEPGEV 494

Query: 424 GISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPA-----EVLSTSEIPFSGVK 478
           GISA+NRNFKGRMGS+DALAYLASP VVAASA+ G IS P      E  S  E  F    
Sbjct: 495 GISASNRNFKGRMGSRDALAYLASPEVVAASALSGVISGPGAYQVPENWSGVEHGFGTGL 554

Query: 479 TEIIENPVVE---------EEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGI 529
               EN +           + V +  E  K + EIL GFP   SGE+V  DADN++TD I
Sbjct: 555 PPTTENELTNLLQQMESLIDRVESAGEDSKPATEILPGFPERISGEIVFLDADNLDTDNI 614

Query: 530 YPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAK 589
           YPGK TYQD+V K+ MA  CM+NYD EF+    P DI+V+GFNFG GSSREQAATA+LAK
Sbjct: 615 YPGKLTYQDNVSKDDMAAACMQNYDPEFKGIAKPSDILVAGFNFGCGSSREQAATAILAK 674

Query: 590 GINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPK-----ELTRRTGWFLK 644
            I LVV+GSFGNIFSRNSINNAL+ LE+P LI++LR  +   P      +LTRRTGW L 
Sbjct: 675 QIPLVVAGSFGNIFSRNSINNALMGLEVPRLIERLRASFAQPPPGDAGRQLTRRTGWTLT 734

Query: 645 WDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           WDV  + V V EG  +      ++VGEL  N+QEII +GGLE WVK ++
Sbjct: 735 WDVKRSVVEVKEG--ESGESWTEQVGELPANVQEIIAEGGLEAWVKGKV 781
>ref|XP_001791786.1| hypothetical protein SNOG_01131 [Phaeosphaeria nodorum SN15]
 gb|EAT90780.2| hypothetical protein SNOG_01131 [Phaeosphaeria nodorum SN15]
          Length = 1654

 Score =  870 bits (2250), Expect = 0.0,   Method: Composition-based stats.
 Identities = 420/777 (54%), Positives = 510/777 (65%), Gaps = 91/777 (11%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           + +F  S H +      Q LTEKIVQ +AV + EGKV+ SGDYV+++P  CM+HDNSWPV
Sbjct: 52  AASFLPSLHET--PKTPQTLTEKIVQRHAVGVAEGKVLRSGDYVTLQPHRCMTHDNSWPV 109

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GAT+I +PSQIV TLDHD+QNK+EKNL KY  IE+FAKK  +  YPAGRGIGH
Sbjct: 110 ALKFMSIGATRISDPSQIVMTLDHDVQNKTEKNLKKYSQIEDFAKKQDVVFYPAGRGIGH 169

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEGYA+P  + VASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V 
Sbjct: 170 QIMVEEGYAWPGTLAVASDSHSNMYGGIGCLGTPVVRTDAASIWATGKTWWQIPPVAKVN 229

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
           L G +PQGV+GKD+IVAL GLFN D+VLNHAIEFTG  +++ ++P+D RLTIANMTTEWG
Sbjct: 230 LIGTMPQGVTGKDVIVALAGLFNKDEVLNHAIEFTGTDETIGSIPVDDRLTIANMTTEWG 289

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAK---------------- 285
           AL+GLFP+D  L  W + R            +    + + E+                  
Sbjct: 290 ALTGLFPIDSVLHGWLRARATLAAMGEGQAKDHHQQQFVHERIDKLFTATGMVGKQLGHI 349

Query: 286 ---IPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTN 342
                 ADK A YAK+L +DLATL+ YVSGPNSVKV+  + +L +Q+I INKAYLVSCTN
Sbjct: 350 FKPALAADKGAVYAKELFLDLATLSPYVSGPNSVKVATPLIELQEQNIPINKAYLVSCTN 409

Query: 343 SRLSDLQSAADVVCPTGDLN--KVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGC 400
           SR SD+ +AA V       N  K+ K+A  V FY+AAAS   +  A ++G W+ LL+AG 
Sbjct: 410 SRASDIAAAARVFKDAAVANGDKIPKIADHVSFYIAAASIPEQKTAEEAGDWQTLLEAGA 469

Query: 401 IPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKI 460
            PLP+GCGPCIGLG GLLEPGEVGISA+NRNFKGRMGS DA AYLASP VVAASA+ G I
Sbjct: 470 QPLPAGCGPCIGLGTGLLEPGEVGISASNRNFKGRMGSPDAKAYLASPEVVAASALSGSI 529

Query: 461 SSPAEVLSTS--------------EIPFSGVKTEIIENPVVEEEVNA----QTEAPKQS- 501
           S P    +                E        +++E  + + E        TE+  QS 
Sbjct: 530 SGPGRYEAPEGYEGVRRGEGDGILEENRMMTIEDMLEKAIKDAEAAIGSFGATESETQSA 589

Query: 502 -------------VEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQV 548
                         EIL GFP +  GE+V CDADNINTDGIYPGKYTYQDDV +EKMA+V
Sbjct: 590 HPSAASGAEVETLTEILPGFPEKIHGEIVFCDADNINTDGIYPGKYTYQDDVTREKMAEV 649

Query: 549 CMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSI 608
           CMENYD  F      GDI+VSGFNFG GSSREQAATA+LAKGI LVV+GSFGNIFSRNSI
Sbjct: 650 CMENYDVGFGQTAKAGDILVSGFNFGCGSSREQAATAILAKGIPLVVAGSFGNIFSRNSI 709

Query: 609 NNALLTLEIPALIKKLREKYQGAP--------------------------------KELT 636
           NNAL+ +E+P L  +LRE +  A                                 K+LT
Sbjct: 710 NNALMGVEVPRLTNRLREVFSSANTASSQQAIKEPSQNRESLDSPPPAATSQPAESKQLT 769

Query: 637 RRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           RRTGW L+WD+  + V V EG          +VGEL  N+QEII  GGLE WVK ++
Sbjct: 770 RRTGWTLEWDIRRSTVTVQEGPN--GDKWNVRVGELPPNVQEIIALGGLENWVKKEI 824
>gb|EDU46563.1| homoaconitase, mitochondrial precursor [Pyrenophora
           tritici-repentis Pt-1C-BFP]
          Length = 837

 Score =  867 bits (2242), Expect = 0.0,   Method: Composition-based stats.
 Identities = 419/774 (54%), Positives = 506/774 (65%), Gaps = 88/774 (11%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           + +F  S + +      Q LTEKIVQ +AV + +GK++ SGDYV+++P  CM+HDNSWPV
Sbjct: 63  AASFLSSLNETPKI--PQTLTEKIVQRHAVGVAQGKILRSGDYVTLQPHKCMTHDNSWPV 120

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFMG+GATKI +P QIV TLDHD+QNK+EKNL KY  IE FAKK  +  YPAGRGIGH
Sbjct: 121 ALKFMGIGATKINDPKQIVMTLDHDVQNKTEKNLKKYSQIEEFAKKQDVVFYPAGRGIGH 180

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEGYA+P  + VASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V 
Sbjct: 181 QIMVEEGYAWPGTLAVASDSHSNMYGGIGCLGTPVVRTDAASIWATGKTWWQIPPVAKVT 240

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
           L G++PQGV+GKD+IVAL GLFN D+VLNHAIEFTG  ++L ++P+D RLTIANMTTEWG
Sbjct: 241 LNGKMPQGVTGKDVIVALAGLFNKDEVLNHAIEFTGTDETLGSIPVDDRLTIANMTTEWG 300

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAK---------------- 285
           AL+GLFP+D  L  W + R            +    + + E+                  
Sbjct: 301 ALTGLFPIDSVLHGWLRARATLAAMGEGQTKDHHQQQFVHERIDKLFTATGIVGEKLGHI 360

Query: 286 ---IPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTN 342
                 ADK A YAK+L +DL+TL+ YVSGPNSVKV+  + +L  Q+I INKAYLVSCTN
Sbjct: 361 FKPALAADKGAVYAKELFLDLSTLSPYVSGPNSVKVATPLLELQSQNIPINKAYLVSCTN 420

Query: 343 SRLSDLQSAADVVCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGC 400
           SR SD+ +AA+V      LN     K+   V FY+AAAS   +  A ++G W+ LL+AG 
Sbjct: 421 SRASDIAAAANVFKDAAVLNGGKIPKIPDHVNFYIAAASIPEQKAAEEAGDWQILLEAGA 480

Query: 401 IPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKI 460
            PLPSGCGPCIGLG GLLEPGEVGISA+NRNFKGRMGS DA AYLASP VVAASA+ G I
Sbjct: 481 QPLPSGCGPCIGLGTGLLEPGEVGISASNRNFKGRMGSPDAKAYLASPEVVAASALSGTI 540

Query: 461 SSPAEVL-----------STSEIPFSG---VKTEIIENPVVEEE---------------V 491
           S P                   IP         +++E  + + E               V
Sbjct: 541 SGPGWYEAPEGYEGVRRGEGDGIPAEERMMTIEDMLEKAIKDAEAAIDTFGSDSSETQSV 600

Query: 492 NAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCME 551
              T   +   EIL GFP + SGE+V CDADNINTDGIYPGKYTYQDDV +EKMA+VCME
Sbjct: 601 TPPTSDAETLTEILPGFPEKISGEIVFCDADNINTDGIYPGKYTYQDDVTREKMAEVCME 660

Query: 552 NYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNA 611
           NYD  F      GDI+VSGFNFG GSSREQAATA+LAKGI LVV+GSFGNIFSRNSINNA
Sbjct: 661 NYDPSFGQMAKAGDILVSGFNFGCGSSREQAATAILAKGIPLVVAGSFGNIFSRNSINNA 720

Query: 612 LLTLEIPALIKKLREKYQGAP--------------------------------KELTRRT 639
           L+ +E+P L  +LRE +                                    K+LTRRT
Sbjct: 721 LMGVEVPKLANRLREAFSSKDASSSQQAIKEPSNNRESLDSPPPAAAAQPTQAKQLTRRT 780

Query: 640 GWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GW L+WDV  + V V EG          KVGEL  N+QEII  GGLE WVK ++
Sbjct: 781 GWTLEWDVRRSTVSVQEGPN--GSKWNVKVGELPPNVQEIIALGGLENWVKKEI 832
>ref|XP_391125.1| hypothetical protein FG10949.1 [Gibberella zeae PH-1]
 sp|Q4HVQ9|LYS4_GIBZE Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
          Length = 776

 Score =  867 bits (2241), Expect = 0.0,   Method: Composition-based stats.
 Identities = 404/709 (56%), Positives = 496/709 (69%), Gaps = 42/709 (5%)

Query: 20  GQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPS 79
            Q L EKI Q YAV L  GK + +GDY+++ P HCMSHDN+WP+A KF+ +GA+KI N  
Sbjct: 73  PQTLVEKIAQQYAVGLAPGKKIKAGDYIALAPHHCMSHDNTWPIAKKFLDIGASKIHNNR 132

Query: 80  QIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTV 139
           Q+V TLDHD+QNKSE NL KY  I  FA+KH + HYPAGRGIGHQIM+EEGYA+P  ++V
Sbjct: 133 QVVFTLDHDVQNKSEANLKKYSLIHEFAEKHGVIHYPAGRGIGHQIMVEEGYAWPGTVSV 192

Query: 140 ASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIV 199
           ASDSHSN YGG+G LGT +VRTDAA+IWATGQTWWQ+PPVA+V   G LP GV+GKD+I+
Sbjct: 193 ASDSHSNMYGGIGCLGTAVVRTDAASIWATGQTWWQVPPVAKVTFTGILPPGVTGKDVII 252

Query: 200 ALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKN 259
           ALCGLF +DQVLNHA+EF G    +LPID RLTI+NMTTEWGAL+G+FPVD+ LI WY+ 
Sbjct: 253 ALCGLFRDDQVLNHAVEFAGG--ESLPIDDRLTISNMTTEWGALAGVFPVDEMLISWYRG 310

Query: 260 RLQK---LGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSV 316
           +       G ++  RIN K +  LE+     +AD +A YAK+L ++L+TL+  V+GPNSV
Sbjct: 311 KATTNAMFGGSSKDRINHKRVDELEQ--NRLEADPNAKYAKELYLNLSTLSPIVAGPNSV 368

Query: 317 KVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVA 376
           K++  +++L  +DI +NKAYLVSCTNSR SD+ +AA V       NK  K+APGV FY+A
Sbjct: 369 KIATPLKNLEAEDIPVNKAYLVSCTNSRASDIAAAARVFREAAKENKDVKIAPGVNFYIA 428

Query: 377 AASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRM 436
           AAS   +  A ++G W+ L  AG   LP+GCGPCIGLG GLLEPGEVGISA+NRNFKGRM
Sbjct: 429 AASLPEQEIAEEAGDWQVLRDAGAQVLPAGCGPCIGLGTGLLEPGEVGISASNRNFKGRM 488

Query: 437 GSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGV------------------- 477
           GS  A AYLASP +VAASA+ GKI+ P        +    +                   
Sbjct: 489 GSTSAKAYLASPEIVAASALKGKIAGPGWYQKPEGVEKVIIGEGSGDYVADKALSIEDAL 548

Query: 478 ------------KTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNIN 525
                         E  E    +       E  +   EIL GFP +  GE+V CD+DNIN
Sbjct: 549 DKLINEADALIAAAETSEGAKEQAASPTAAEGEESLTEILPGFPEKVEGEIVFCDSDNIN 608

Query: 526 TDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATA 585
           TDGIYPGKYTYQD+V  EKMA+VCMENYD EF      GDI+V+GFNFG GSSREQAATA
Sbjct: 609 TDGIYPGKYTYQDNVSVEKMAEVCMENYDTEFGKFAKAGDILVTGFNFGCGSSREQAATA 668

Query: 586 LLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGA-PKELTRRTGWFLK 644
           LLAK I LVVSGSFGNIFSRNSINNAL+ +E+P L+++LRE Y+    K LTRRTGW L 
Sbjct: 669 LLAKKIPLVVSGSFGNIFSRNSINNALMGVEVPRLVERLRETYKNDTEKPLTRRTGWKLV 728

Query: 645 WDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           WDV  +KV+VTE         EQKVGEL  N+QEII +GGLE WVK+++
Sbjct: 729 WDVRRSKVIVTEKD---GSSWEQKVGELPANVQEIIARGGLEKWVKAKI 774
>ref|XP_001547913.1| hypothetical protein BC1G_13341 [Botryotinia fuckeliana B05.10]
 gb|EDN19663.1| hypothetical protein BC1G_13341 [Botryotinia fuckeliana B05.10]
          Length = 806

 Score =  864 bits (2234), Expect = 0.0,   Method: Composition-based stats.
 Identities = 419/757 (55%), Positives = 502/757 (66%), Gaps = 71/757 (9%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S+    S  ++      Q LTEKIVQ Y++ L + KVV SGDYV++ P +CM+HDNSWPV
Sbjct: 51  SSAILSSLKTTPRV--AQTLTEKIVQRYSLGLAKDKVVKSGDYVTLSPHYCMTHDNSWPV 108

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           A KFM +GATKI N +QIV TLDHD+QNKSE NL KYK IE FA++  +D YPAGRGIGH
Sbjct: 109 ATKFMSIGATKIHNTNQIVCTLDHDVQNKSETNLKKYKQIEEFARQQGVDFYPAGRGIGH 168

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEGYA+P  +TVASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V 
Sbjct: 169 QIMVEEGYAWPGTVTVASDSHSNMYGGIGCLGTPMVRTDAASIWATGRTWWQIPPIAKVT 228

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWG 241
           L G LP GV+GKD+IVALCGLFN+D VLNHAIEFTG   ++ +LPID RLTIANMTTEWG
Sbjct: 229 LTGVLPIGVTGKDVIVALCGLFNSDDVLNHAIEFTGSEQTMRSLPIDDRLTIANMTTEWG 288

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLG---TNNHPRINPKTIRALEEKAKIPKADKDAHYAKK 298
           ALSGLFP+D  L  W + +          N   +     R  +       ADK A YAK 
Sbjct: 289 ALSGLFPIDSVLEKWLRYKATTSAMFDPKNGKELRFTHARIDDLVQNQLVADKGATYAKS 348

Query: 299 LIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPT 358
           L ++L+TL+ YV+GPNSVK++  ++DL  Q IK+NKAYLVSCTNSR SDL +AA V    
Sbjct: 349 LYLNLSTLSPYVAGPNSVKIATPIRDLEAQKIKLNKAYLVSCTNSRASDLAAAAKVFKDA 408

Query: 359 GDLNKVN---KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGA 415
            + +      K+  GV FY+AAAS   +  A ++G W+ LL AG  PLPSGCGPCIGLG 
Sbjct: 409 AESSPDKTIPKIPEGVNFYIAAASIPEQEAAEEAGDWQALLAAGAQPLPSGCGPCIGLGT 468

Query: 416 GLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLST------ 469
           GLLEPGEVGISA+NRNFKGRMGS DA AYLASP VVAASA+ G IS P            
Sbjct: 469 GLLEPGEVGISASNRNFKGRMGSTDAKAYLASPEVVAASALSGYISGPGWYQPPIGVNKV 528

Query: 470 --------SEIPFSGVKTEIIENPVVEEEVNAQ-------------TEAPKQSV-EILEG 507
                    E   +    E +E  + + E                  E   +S+ EIL G
Sbjct: 529 VLGEGNGNVEEDKAISIEEALEKLISQAESIVDGAESSLFGTSSKPEETDSESLTEILPG 588

Query: 508 FPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIV 567
           FP +  GE+V CDADN+NTD IYPGKYTYQD V  EKMA+VCMENYD EFRT    GDI+
Sbjct: 589 FPEKVEGEIVFCDADNVNTDAIYPGKYTYQDGVSVEKMAEVCMENYDKEFRTIAREGDIL 648

Query: 568 VSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREK 627
           VSGFNFG GSSREQAATA+LAK I +VV+GSFGNIFSRNSINNAL+ +E+P L+++LRE 
Sbjct: 649 VSGFNFGCGSSREQAATAILAKKIPMVVAGSFGNIFSRNSINNALMGVEVPRLVQRLREH 708

Query: 628 YQG-------------------------------APKELTRRTGWFLKWDVADAKVVVTE 656
           +                                   K LTRRTGW   WDV  +KV V E
Sbjct: 709 FAASAPVPKKEVTEPSENSESLDSPKPAEQAVPQGEKILTRRTGWKFVWDVRRSKVEVQE 768

Query: 657 GSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           G  +G     QKVGEL  N+QEII +GGLE WVK +L
Sbjct: 769 G--EGGEKWSQKVGELPPNVQEIIARGGLEKWVKGEL 803
>ref|XP_001598937.1| hypothetical protein SS1G_01026 [Sclerotinia sclerotiorum 1980]
 gb|EDN91623.1| hypothetical protein SS1G_01026 [Sclerotinia sclerotiorum 1980]
          Length = 806

 Score =  863 bits (2232), Expect = 0.0,   Method: Composition-based stats.
 Identities = 415/759 (54%), Positives = 502/759 (66%), Gaps = 75/759 (9%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S+    S  ++      Q LTEKIVQ Y++ L + K V SGDYV++ P +CM+HDNSWPV
Sbjct: 51  SSAILSSLKTTPRV--AQTLTEKIVQRYSLGLAKDKFVKSGDYVTLSPHYCMTHDNSWPV 108

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           A KFM +GATKI N +QIV TLDHD+QNKSE NL KYK IE FA++  +D YPAGRGIGH
Sbjct: 109 ATKFMSIGATKIHNTNQIVCTLDHDVQNKSETNLKKYKQIEEFARQQGVDFYPAGRGIGH 168

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEGYA+P  +TVASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V 
Sbjct: 169 QIMVEEGYAWPGTVTVASDSHSNMYGGIGCLGTPMVRTDAASIWATGRTWWQIPPIAKVT 228

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWG 241
           L G LP GV+GKD+IVALCGLFN+D VLNHAIEFTG   ++ +L +D RLTIANMTTEWG
Sbjct: 229 LTGVLPIGVTGKDVIVALCGLFNSDDVLNHAIEFTGSEQTMRSLSVDDRLTIANMTTEWG 288

Query: 242 ALSGLFPVDKTLIDWYKNRLQ-----KLGTNNHPRINPKTIRALEEKAKIPKADKDAHYA 296
           ALSGLFP+D  L  W + +              PR     I  L +      ADK A YA
Sbjct: 289 ALSGLFPIDSVLESWLRYKATTSAMFAPENGKEPRFTHARIDDLVQ--NQLVADKGATYA 346

Query: 297 KKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVC 356
           K L ++L+TL+ YV+GPNSVK++  ++DL  Q IK+N+AYLVSCTNSR SDL +AA V  
Sbjct: 347 KSLYLNLSTLSPYVAGPNSVKIATPIRDLEAQKIKLNRAYLVSCTNSRASDLAAAAKVFK 406

Query: 357 PTGDLNKVN---KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGL 413
              + +      K+A GV FY+AAAS   +  A  +G W+ LL AG  PLPSGCGPCIGL
Sbjct: 407 DAAESSPDKTIPKIAEGVNFYIAAASIPEQEAAEAAGDWQALLAAGAQPLPSGCGPCIGL 466

Query: 414 GAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIP 473
           G GLLEPGEVGISA+NRNFKGRMGS DA AYLASP +VAASA+ G ISSP        + 
Sbjct: 467 GTGLLEPGEVGISASNRNFKGRMGSTDAKAYLASPELVAASALSGYISSPGWYEQPVGVN 526

Query: 474 F-----SGVKTEIIENPVVEEE-------VNAQTEAPKQSV----------------EIL 505
                      E  +   +EE          +  +  + S+                EIL
Sbjct: 527 KVVLGEGNGNVEEDKAISIEEALEKLISQAESIVDGAESSLFGTSSKSDETETETLTEIL 586

Query: 506 EGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGD 565
            GFP +  GE+V CDADN+NTD IYPGKYTYQD V  EKMA+VCMENYD EFRT    GD
Sbjct: 587 PGFPEKVEGEIVFCDADNVNTDAIYPGKYTYQDGVSVEKMAEVCMENYDKEFRTIAREGD 646

Query: 566 IVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLR 625
           I+VSGFNFG GSSREQAATA+LAK I +VV+GSFGNIFSRNSINNAL+ +E+P L+++LR
Sbjct: 647 ILVSGFNFGCGSSREQAATAILAKKIPMVVAGSFGNIFSRNSINNALMGVEVPRLVQRLR 706

Query: 626 EKYQG-------------------------------APKELTRRTGWFLKWDVADAKVVV 654
           E +                                   K LTRRTGW   WDV  +KV V
Sbjct: 707 EHFAASAPVPKKEVTEPSENSESLDSPKPAEQAVPQGEKILTRRTGWKFVWDVRRSKVEV 766

Query: 655 TEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            EG  +G     QKVGEL  N+QEII +GGLE WVK+++
Sbjct: 767 QEG--EGGEKWSQKVGELPPNVQEIIARGGLEKWVKAEI 803
>ref|XP_001274165.1| homoaconitase LysF [Aspergillus clavatus NRRL 1]
 gb|EAW12739.1| homoaconitase LysF [Aspergillus clavatus NRRL 1]
          Length = 777

 Score =  860 bits (2223), Expect = 0.0,   Method: Composition-based stats.
 Identities = 401/715 (56%), Positives = 494/715 (69%), Gaps = 31/715 (4%)

Query: 6   TFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVAL 65
           + +       A    Q LTEKIVQ+Y++ L +G+ V +GDYV + P  CM+HDNSWP AL
Sbjct: 64  SPSTRPSPDAAPRVPQTLTEKIVQAYSLGLKDGQYVKAGDYVMLSPHRCMTHDNSWPTAL 123

Query: 66  KFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQI 125
           KFM +GA+KI NP QIV TLDHD+QNKSEKNL KY+ IE FA KH +D YPAG G+GHQI
Sbjct: 124 KFMAIGASKIHNPDQIVMTLDHDVQNKSEKNLKKYEQIEQFADKHGVDFYPAGHGVGHQI 183

Query: 126 MIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELK 185
           MIEEGYAFP  +TVASDSHSN YGG+G LGTP+VRTDAA IWATG+TWW++PP+A+V+  
Sbjct: 184 MIEEGYAFPGTVTVASDSHSNMYGGVGCLGTPMVRTDAATIWATGRTWWKVPPIAKVQFT 243

Query: 186 GQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGAL 243
           G LP+GV+GKD+IVAL GLFN D+VLN+AIEFTG  +++ +L +D RLTIANMTTEWGAL
Sbjct: 244 GTLPEGVTGKDVIVALSGLFNKDEVLNYAIEFTGSEETMKSLSVDTRLTIANMTTEWGAL 303

Query: 244 SGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDL 303
           +GLFP+D TL  W +N+      +   R   +  R  E  A    AD+ A YAK L +DL
Sbjct: 304 TGLFPIDSTLEQWLRNKATTASRSETARRFAEE-RINELFANPTVADRGAKYAKYLYLDL 362

Query: 304 ATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNK 363
           +TL+ YVSGPNSVKV+  V +L+QQ +K+NKAYLVSCTNSR SD+ +AA V         
Sbjct: 363 STLSPYVSGPNSVKVATPVDELAQQKLKVNKAYLVSCTNSRASDIAAAAKVFKDAAARTG 422

Query: 364 VN-KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGE 422
              K+A GVEFYVAAAS   +  A ++G W+ LL AG I LP+GC  CIGLGAGLL+ GE
Sbjct: 423 GPVKIAEGVEFYVAAASKAEQKIAVQAGDWQALLDAGAIALPAGCAVCIGLGAGLLKDGE 482

Query: 423 VGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEV----------LSTSEI 472
           +GISA+NRNFKGRMGS DA AYLASP VVAASA+ G IS P             L   E+
Sbjct: 483 IGISASNRNFKGRMGSPDAKAYLASPEVVAASALNGIISGPGIYKRPEDWSGVSLGEGEV 542

Query: 473 PFSGVKTEI----------IENPVVEEEVNAQTEAPKQS----VEILEGFPREFSGELVL 518
             SG + +             + ++E    A       S    ++I+ GFP +  GE++ 
Sbjct: 543 VESGNRIDTTLETMEKFLGQLDSMIESSSKAVMPEESTSETTEIDIVPGFPEKVEGEILF 602

Query: 519 CDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSS 578
            DADNI+TDGIYPGKYTYQDDV KEKMAQVCMENYD  F      GDI VSGFNFG GSS
Sbjct: 603 LDADNISTDGIYPGKYTYQDDVSKEKMAQVCMENYDPAFNNVARAGDIFVSGFNFGCGSS 662

Query: 579 REQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRR 638
           REQAAT++LAK + LVV GS GN FSRN++NNAL  LE+P L+++LRE + G  K+ TRR
Sbjct: 663 REQAATSILAKQLPLVVCGSIGNTFSRNAVNNALPLLEMPRLVERLREAF-GNDKQPTRR 721

Query: 639 TGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           TGW   W+V  ++V V EG   G     Q V  L  NLQ+II +GGLE WVK ++
Sbjct: 722 TGWSFTWNVRTSQVTVQEGP--GGETWTQSVPALPPNLQDIIAQGGLEKWVKKEI 774
>ref|XP_753748.1| homoaconitase LysF [Aspergillus fumigatus Af293]
 sp|Q4WUL6|LYS4_ASPFU Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|EAL91710.1| homoaconitase LysF [Aspergillus fumigatus Af293]
          Length = 777

 Score =  860 bits (2222), Expect = 0.0,   Method: Composition-based stats.
 Identities = 396/711 (55%), Positives = 489/711 (68%), Gaps = 32/711 (4%)

Query: 11  FHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGL 70
                A    Q LTEKIVQ+Y++ L EG+ V +GDYV + P  CM+HDNSWP ALKFM +
Sbjct: 68  PAPDAAPRVPQTLTEKIVQAYSLGLAEGQYVKAGDYVMLSPHRCMTHDNSWPTALKFMAI 127

Query: 71  GATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEG 130
           GA+K+ NP QIV TLDHD+QNKSEKNL KY++IE FAK+H ID YPAG G+GHQIMIEEG
Sbjct: 128 GASKVHNPDQIVMTLDHDVQNKSEKNLKKYESIEKFAKQHGIDFYPAGHGVGHQIMIEEG 187

Query: 131 YAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQ 190
           YAFP  +TVASDSHSN YGG+G LGTP+VRTDAA IWATG+TWW++PP+A+V+  G LP+
Sbjct: 188 YAFPGTVTVASDSHSNMYGGVGCLGTPMVRTDAATIWATGRTWWKVPPIAKVQFTGTLPE 247

Query: 191 GVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFP 248
           GV+GKD+IVAL GLFN D+VLN+AIEFTG  +++ +L +D RLTIANMTTEWGAL+GLFP
Sbjct: 248 GVTGKDVIVALSGLFNKDEVLNYAIEFTGSEETMKSLSVDTRLTIANMTTEWGALTGLFP 307

Query: 249 VDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           +D TL  W +++          R   +  R  E  A    AD+ A YAK L +DL+TL+ 
Sbjct: 308 IDSTLEQWLRHKAATASRTETARRFAEE-RINELFANPTVADRGARYAKYLYLDLSTLSP 366

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVN-KV 367
           YVSGPNSVKV+  + +L +  +KI+KAYLVSCTNSR SD+ +AA V            +V
Sbjct: 367 YVSGPNSVKVATPLDELEKHKLKIDKAYLVSCTNSRASDIAAAAKVFKDAVARTGGPVRV 426

Query: 368 APGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISA 427
           A GVEFYVAAAS   +  A ++G W+ L+ AG IPLP+GC  CIGLGAGLL+ GEVGISA
Sbjct: 427 ADGVEFYVAAASKAEQKIAEEAGDWQALMDAGAIPLPAGCAVCIGLGAGLLKEGEVGISA 486

Query: 428 TNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSE---------------- 471
           +NRNFKGRMGS DA AYLASP VVAASA+ G IS P       +                
Sbjct: 487 SNRNFKGRMGSPDAKAYLASPEVVAASALNGVISGPGIYKRPEDWTGVSIGEGEVVESGS 546

Query: 472 ---------IPFSGVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDAD 522
                      F G    +I++          T +    V+I+ GFP +  GE++  DAD
Sbjct: 547 RIDTTLEAMEKFIGQLDSMIDSSSKAVMPEESTGSGATEVDIVPGFPEKIEGEILFLDAD 606

Query: 523 NINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQA 582
           NI+TDGIYPGKYTYQDDV K+KMAQVCMENYD  F      GDI VSGFNFG GSSREQA
Sbjct: 607 NISTDGIYPGKYTYQDDVTKDKMAQVCMENYDPAFSGIARAGDIFVSGFNFGCGSSREQA 666

Query: 583 ATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWF 642
           AT++LAK + LVV+GS GN FSRN++NNAL  LE+P LI++LRE + G+ K+ TRRTGW 
Sbjct: 667 ATSILAKQLPLVVAGSIGNTFSRNAVNNALPLLEMPRLIERLREAF-GSEKQPTRRTGWT 725

Query: 643 LKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
             W+V  ++V V EG   G     Q V     NLQ+II +GGLE WVK ++
Sbjct: 726 FTWNVRTSQVTVQEGP--GGETWSQSVPAFPPNLQDIIAQGGLEKWVKKEI 774
>gb|EDP51631.1| homoaconitase LysF [Aspergillus fumigatus A1163]
          Length = 777

 Score =  858 bits (2218), Expect = 0.0,   Method: Composition-based stats.
 Identities = 395/711 (55%), Positives = 488/711 (68%), Gaps = 32/711 (4%)

Query: 11  FHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGL 70
                A    Q LTEKIVQ+Y++ L EG+ V +GDYV + P  CM+HDNSWP ALKFM +
Sbjct: 68  PAPDAAPRVPQTLTEKIVQAYSLGLAEGQYVKAGDYVMLSPHRCMTHDNSWPTALKFMAI 127

Query: 71  GATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEG 130
           GA+K+ NP QIV TLDHD+QNKSEKNL KY++IE FA +H ID YPAG G+GHQIMIEEG
Sbjct: 128 GASKVHNPDQIVMTLDHDVQNKSEKNLKKYESIEKFANQHGIDFYPAGHGVGHQIMIEEG 187

Query: 131 YAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQ 190
           YAFP  +TVASDSHSN YGG+G LGTP+VRTDAA IWATG+TWW++PP+A+V+  G LP+
Sbjct: 188 YAFPGTVTVASDSHSNMYGGVGCLGTPMVRTDAATIWATGRTWWKVPPIAKVQFTGTLPE 247

Query: 191 GVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFP 248
           GV+GKD+IVAL GLFN D+VLN+AIEFTG  +++ +L +D RLTIANMTTEWGAL+GLFP
Sbjct: 248 GVTGKDVIVALSGLFNKDEVLNYAIEFTGSEETMKSLSVDTRLTIANMTTEWGALTGLFP 307

Query: 249 VDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           +D TL  W +++          R   +  R  E  A    AD+ A YAK L +DL+TL+ 
Sbjct: 308 IDSTLEQWLRHKAATASRTETARRFAEE-RINELFANPTVADRGARYAKYLYLDLSTLSP 366

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVN-KV 367
           YVSGPNSVKV+  + +L +  +KI+KAYLVSCTNSR SD+ +AA V            +V
Sbjct: 367 YVSGPNSVKVATPLDELEKHKLKIDKAYLVSCTNSRASDIAAAAKVFKDAVARTGGPVRV 426

Query: 368 APGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISA 427
           A GVEFYVAAAS   +  A ++G W+ L+ AG IPLP+GC  CIGLGAGLL+ GEVGISA
Sbjct: 427 ADGVEFYVAAASKAEQKIAEEAGDWQALMDAGAIPLPAGCAVCIGLGAGLLKEGEVGISA 486

Query: 428 TNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSE---------------- 471
           +NRNFKGRMGS DA AYLASP VVAASA+ G IS P       +                
Sbjct: 487 SNRNFKGRMGSPDAKAYLASPEVVAASALNGVISGPGIYKRPEDWTGVSIGEGEVVESGS 546

Query: 472 ---------IPFSGVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDAD 522
                      F G    +I++          T +    V+I+ GFP +  GE++  DAD
Sbjct: 547 RIDTTLEAMEKFIGQLDSMIDSSSKAVMPEESTGSGATEVDIVPGFPEKIEGEILFLDAD 606

Query: 523 NINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQA 582
           NI+TDGIYPGKYTYQDDV K+KMAQVCMENYD  F      GDI VSGFNFG GSSREQA
Sbjct: 607 NISTDGIYPGKYTYQDDVTKDKMAQVCMENYDPAFSGIARAGDIFVSGFNFGCGSSREQA 666

Query: 583 ATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWF 642
           AT++LAK + LVV+GS GN FSRN++NNAL  LE+P LI++LRE + G+ K+ TRRTGW 
Sbjct: 667 ATSILAKQLPLVVAGSIGNTFSRNAVNNALPLLEMPRLIERLREAF-GSEKQPTRRTGWT 725

Query: 643 LKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
             W+V  ++V V EG   G     Q V     NLQ+II +GGLE WVK ++
Sbjct: 726 FTWNVRTSQVTVQEGP--GGETWSQSVPAFPPNLQDIIAQGGLEKWVKKEI 774
>emb|CAC48042.1| homoaconitase [Aspergillus fumigatus]
          Length = 777

 Score =  858 bits (2217), Expect = 0.0,   Method: Composition-based stats.
 Identities = 395/711 (55%), Positives = 488/711 (68%), Gaps = 32/711 (4%)

Query: 11  FHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGL 70
                A    Q LTEKIVQ+Y++ L EG+ V +GDYV + P  CM+HDNSWP ALKFM +
Sbjct: 68  PAPDAAPRVPQTLTEKIVQAYSLGLAEGQYVKAGDYVMLSPHRCMTHDNSWPTALKFMAI 127

Query: 71  GATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEG 130
           GA+K+ NP QIV TLDHD+QNKSEKNL KY++IE FA +H ID YPAG G+GHQIMIEEG
Sbjct: 128 GASKVHNPDQIVMTLDHDVQNKSEKNLKKYESIEKFANQHGIDFYPAGHGVGHQIMIEEG 187

Query: 131 YAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQ 190
           YAFP  +TVASDSHSN YGG+G LGTP+VRTDAA IWATG+TWW++PP+A+V+  G LP+
Sbjct: 188 YAFPGTVTVASDSHSNMYGGVGCLGTPMVRTDAATIWATGRTWWKVPPIAKVQFTGTLPE 247

Query: 191 GVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFP 248
           GV+GKD+IVAL GLFN D+VLN+AIEFTG  +++ +L +D RLTIANMTTEWGAL+GLFP
Sbjct: 248 GVTGKDVIVALSGLFNKDEVLNYAIEFTGSEETMKSLSVDTRLTIANMTTEWGALTGLFP 307

Query: 249 VDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           +D TL  W +++          R   +  R  E  A    AD+ A YAK L +DL+TL+ 
Sbjct: 308 IDSTLEQWLRHKAATASRTETARRFAEE-RINELFANPTVADRGARYAKYLYLDLSTLSP 366

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVN-KV 367
           YVSGPNSVKV+  + +L +  +KI+KAYLVSCTNSR SD+ +AA V            +V
Sbjct: 367 YVSGPNSVKVATPLDELEKHKLKIDKAYLVSCTNSRASDIAAAAKVFKDAVARTGGPVRV 426

Query: 368 APGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISA 427
           A GVEFYVAAAS   +  A ++G W+ L+ AG IPLP+GC  CIGLGAGLL+ GEVGISA
Sbjct: 427 ADGVEFYVAAASKAEQKIAEEAGDWQALMDAGAIPLPAGCAVCIGLGAGLLKEGEVGISA 486

Query: 428 TNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSE---------------- 471
           +NRNFKGRMGS DA AYLASP VVAASA+ G IS P       +                
Sbjct: 487 SNRNFKGRMGSPDAKAYLASPEVVAASALNGVISGPGIYKRPEDWTGVSIGEGEVVESGS 546

Query: 472 ---------IPFSGVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDAD 522
                      F G    +I++          T +    V+I+ GFP +  GE++  DAD
Sbjct: 547 RIDTTLEAMEKFIGQLDSMIDSSSKAVMPEESTGSGATEVDIVPGFPEKIEGEILFLDAD 606

Query: 523 NINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQA 582
           NI+TDGIYPGKYTYQDDV K+KMAQVCMENYD  F      GDI VSGFNFG GSSREQA
Sbjct: 607 NISTDGIYPGKYTYQDDVTKDKMAQVCMENYDPAFSGIARAGDIFVSGFNFGCGSSREQA 666

Query: 583 ATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWF 642
           AT++LAK + LVV+GS GN FSRN++NNAL  LE+P LI++LRE + G+ K+ TRRTGW 
Sbjct: 667 ATSILAKQLPLVVAGSIGNTFSRNAVNNALPLLEMPRLIERLREAF-GSEKQPTRRTGWT 725

Query: 643 LKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
             W+V  ++V V EG   G     Q V     NLQ+II +GGLE WVK ++
Sbjct: 726 FTWNVRTSQVTVQEGP--GGETWSQSVPAFPPNLQDIIAQGGLEKWVKKEI 774
>ref|XP_001259799.1| homoaconitase LysF [Neosartorya fischeri NRRL 181]
 gb|EAW17902.1| homoaconitase LysF [Neosartorya fischeri NRRL 181]
          Length = 777

 Score =  854 bits (2208), Expect = 0.0,   Method: Composition-based stats.
 Identities = 395/707 (55%), Positives = 488/707 (69%), Gaps = 32/707 (4%)

Query: 15  RAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATK 74
            A    Q LTEKIVQ+Y++ L EG+ V +GDYV + P  CM+HDNSWP ALKFM +GA+K
Sbjct: 72  AAPRVPQTLTEKIVQAYSLGLAEGQYVKAGDYVMLSPHRCMTHDNSWPTALKFMAIGASK 131

Query: 75  IKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFP 134
           + NP+QIV TLDHD+QNKSEKNL KY++IE FA +H ID YPAG G+GHQIMIEEGYAFP
Sbjct: 132 VHNPNQIVMTLDHDVQNKSEKNLKKYESIEKFANQHGIDFYPAGHGVGHQIMIEEGYAFP 191

Query: 135 LNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSG 194
             +TVASDSHSN YGG+G LGTP+VRTDAA IWATG+TWW++PP+A+V+  G LP+GV+G
Sbjct: 192 GTVTVASDSHSNMYGGVGCLGTPMVRTDAATIWATGRTWWKVPPIAKVQFTGTLPEGVTG 251

Query: 195 KDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKT 252
           KD+IVAL GLFN D+VLN+AIEFTG  +++ +L +D RLTIANMTTEWGAL+GLFP+D T
Sbjct: 252 KDVIVALSGLFNKDEVLNYAIEFTGSEETMKSLSVDTRLTIANMTTEWGALTGLFPIDLT 311

Query: 253 LIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSG 312
           L  W +++          R   +  R  E  A    AD+ A YAK L +DL+TL+ YVSG
Sbjct: 312 LEQWLRHKAATASRTETARRFAEE-RINELFANPTVADRGAKYAKYLYLDLSTLSPYVSG 370

Query: 313 PNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVN-KVAPGV 371
           PNSVKV+  + +L +  +KI+KAYLVSCTNSR SD+ +AA V             VA GV
Sbjct: 371 PNSVKVATPIDELEKHKLKIDKAYLVSCTNSRASDIAAAAKVFKDAVARTGGPVTVADGV 430

Query: 372 EFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRN 431
           EFYVAAAS   +  A ++G W+ L+ AG IPLP+GC  CIGLGAGLL+ GEVGISA+NRN
Sbjct: 431 EFYVAAASKAEQKIAEEAGDWQALMDAGAIPLPAGCAVCIGLGAGLLKEGEVGISASNRN 490

Query: 432 FKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSE-------------------- 471
           FKGRMGS DA AYLASP VVAASA+ G IS P       +                    
Sbjct: 491 FKGRMGSPDAKAYLASPEVVAASALNGVISGPGIYKRPEDWAGVSIGEGEVVESGTRIDT 550

Query: 472 -----IPFSGVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINT 526
                  F G    +IE+          T +    V+I+ GFP +  GE++  DADNI+T
Sbjct: 551 TLEAMEKFIGQLDSMIESSSKAVMPEESTGSGATEVDIVPGFPEKIEGEILFLDADNIST 610

Query: 527 DGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATAL 586
           DGIYPGKYTYQDDV K+KMAQVCMENYD  F      GDI VSGFNFG GSSREQAAT++
Sbjct: 611 DGIYPGKYTYQDDVTKDKMAQVCMENYDPAFSGIARAGDIFVSGFNFGCGSSREQAATSI 670

Query: 587 LAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWD 646
           LAK + LVV+GS GN FSRN++NNAL  LE+P L+++LRE + G+ K+ TRRTGW   W+
Sbjct: 671 LAKQLPLVVAGSIGNTFSRNAVNNALPLLEMPRLVERLREAF-GSEKQPTRRTGWTFTWN 729

Query: 647 VADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           V  ++V V EG   G     Q V     NLQ+II +GGLE WVK ++
Sbjct: 730 VRTSQVTVQEGP--GGETWSQSVPAFPPNLQDIIAQGGLEKWVKKEI 774
>ref|XP_001228555.1| hypothetical protein CHGG_10628 [Chaetomium globosum CBS 148.51]
 sp|Q2GN26|LYS4_CHAGB Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|EAQ84224.1| hypothetical protein CHGG_10628 [Chaetomium globosum CBS 148.51]
          Length = 797

 Score =  850 bits (2196), Expect = 0.0,   Method: Composition-based stats.
 Identities = 405/728 (55%), Positives = 505/728 (69%), Gaps = 50/728 (6%)

Query: 12  HSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLG 71
                    Q LTEKIVQ YA+ LP GK V +GDYV+I PA CM+HDNSWPV  KF  +G
Sbjct: 71  APGTRVQNPQTLTEKIVQRYAIGLPPGKKVKAGDYVTISPAQCMTHDNSWPVVTKFTSIG 130

Query: 72  ATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGY 131
           ATKI N  Q+V TLDHD+QN SE NL KYKNIENFA++H +D YPAGRGIGHQIMIEEGY
Sbjct: 131 ATKIHNNRQVVVTLDHDVQNTSESNLKKYKNIENFARQHGVDFYPAGRGIGHQIMIEEGY 190

Query: 132 AFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQG 191
           A+P  +TVASDSHSN YGG+ +LGTP+VRTDAA+IWATGQTWWQIPP+A+V   G LP+G
Sbjct: 191 AWPGTLTVASDSHSNMYGGVAALGTPVVRTDAASIWATGQTWWQIPPIAKVTFTGVLPRG 250

Query: 192 VSGKDIIVALCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWGALSGLFPV 249
           V+GKD+I+ALC LFN D+VLNHAIEFTG   +L++LPID RLTI+NMTTEWGA++G+FP+
Sbjct: 251 VTGKDVIIALCALFNQDEVLNHAIEFTGSDLTLSSLPIDDRLTISNMTTEWGAVAGIFPI 310

Query: 250 DKTLIDWYKNRLQ--KLGTNNHPRINPKTIRALEEKAK-IPKADKDAHYAKKLIIDLATL 306
           D TL  W + +     +   +       T   +EE  +  PK D  A YAK L ++L+TL
Sbjct: 311 DSTLKSWLRAKATVSAMLNPDLGGKARITHDKIEELFRDPPKPDLGATYAKSLYLNLSTL 370

Query: 307 THYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNK 366
           + +V+GPNSVKV+  V+DL  Q+IKINKAYLVSCTNSR SD+ +AA+V     +   + K
Sbjct: 371 SPFVAGPNSVKVATPVKDLEAQNIKINKAYLVSCTNSRASDIAAAANVFREAANGGPIPK 430

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           VAPGVEFY++AAS   +  A ++G W  LL AGCI  P+ C  CIGLG GLL+PG+VGIS
Sbjct: 431 VAPGVEFYISAASLPEQEIAEQAGDWRVLLDAGCIENPASCNACIGLGRGLLQPGDVGIS 490

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSP----------------------- 463
           A+NRN+ GRMGS  A AYLASP VVAASA+ G+I+ P                       
Sbjct: 491 ASNRNWNGRMGSPQAKAYLASPEVVAASALKGEIAGPGWYEKPEGVEKVIIGEGTGDLEA 550

Query: 464 ----------AEVLSTSEIPFSGVKTEIIENPVVEE--------EVNAQTEAPKQSVEIL 505
                       +++ +E   S  +  +  +P            +  A     +  ++IL
Sbjct: 551 DRAVSIADALESLVAQAESMISSAEKSLESSPAAATGAVGNAMADATADQAGEEGLIDIL 610

Query: 506 EGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGD 565
            GFP + SGE+V CD+DNINTDGIYPGKYTYQDD+ ++ MAQV MENYD  F +   PGD
Sbjct: 611 PGFPEKVSGEIVFCDSDNINTDGIYPGKYTYQDDITRDTMAQVVMENYDRSFASLAKPGD 670

Query: 566 IVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLR 625
           I+V+GFNFG GSSREQAATA+LAKGI LVV+GSFGNIFSRNSINNAL+ +E+P L+K+LR
Sbjct: 671 ILVAGFNFGCGSSREQAATAILAKGIPLVVAGSFGNIFSRNSINNALMGVEVPRLVKRLR 730

Query: 626 EKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGL 685
           E++    K  TRRTGW  +WDV  +KV VTEG  +G     QKVG+L  N+QEII  GGL
Sbjct: 731 EEF--GEKVPTRRTGWRFEWDVRRSKVTVTEG--EGGETWSQKVGDLPPNVQEIIAVGGL 786

Query: 686 EGWVKSQL 693
           E WVK ++
Sbjct: 787 EKWVKHRI 794
>ref|XP_001214855.1| homoaconitase, mitochondrial precursor [Aspergillus terreus
           NIH2624]
 gb|EAU33438.1| homoaconitase, mitochondrial precursor [Aspergillus terreus
           NIH2624]
          Length = 675

 Score =  835 bits (2158), Expect = 0.0,   Method: Composition-based stats.
 Identities = 388/675 (57%), Positives = 475/675 (70%), Gaps = 38/675 (5%)

Query: 55  MSHDNSWPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDH 114
           M+HDNSWPVALKFM +GATK+ NP QIV TLDHD+QNKSEKNL KY+ IE FAK H ++ 
Sbjct: 1   MTHDNSWPVALKFMSIGATKLHNPDQIVMTLDHDVQNKSEKNLQKYRQIEEFAKHHGVEF 60

Query: 115 YPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWW 174
           YPAGRGIGHQIM+EEG+A+P  + VASDSHSN YGG+G LGTP+VRTDAA++W+T QTWW
Sbjct: 61  YPAGRGIGHQIMVEEGFAWPGTLVVASDSHSNMYGGIGCLGTPVVRTDAASLWSTSQTWW 120

Query: 175 QIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLT 232
           QIPPVA++ L G LP GV+GKDIIVALCGLF+ D VLNHA+EFTG  +++ +L +D RLT
Sbjct: 121 QIPPVAKITLTGVLPAGVTGKDIIVALCGLFDKDNVLNHALEFTGSEETMWSLSVDDRLT 180

Query: 233 IANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHP------RINPKTIRALEE-KAK 285
           IANMTTEWGALSGLFP+D TL  W + +                     T  ALEE  A 
Sbjct: 181 IANMTTEWGALSGLFPIDNTLKGWLRGKATTAAMGLADGPFKSLAAKHFTHEALEELFAN 240

Query: 286 IPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRL 345
              ADK A YAK+  +DL+TL+ YV+GPNSVKV+  +++L  Q+IK++KAYL+SCTNSR 
Sbjct: 241 PLAADKGAKYAKEYFLDLSTLSPYVAGPNSVKVATPLKELEAQNIKVDKAYLLSCTNSRA 300

Query: 346 SDLQSAADVVCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
           SD+ +AA V     + N     K+A GV+FY+AAAS   +A A  +G W+ L++AG  PL
Sbjct: 301 SDIAAAARVFREAAEKNGGKVPKIADGVKFYLAAASLPEQAAAEGAGDWQILMEAGATPL 360

Query: 404 PSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSP 463
           P+GCG CIGLG GLLEP EVGISA+NRNFKGRMGS +A AYL SP VVAASA+ GK+S P
Sbjct: 361 PAGCGTCIGLGEGLLEPNEVGISASNRNFKGRMGSVEAKAYLGSPEVVAASALNGKLSGP 420

Query: 464 AEVLSTS--------EIPFSGVKTEIIENPVVEEEVNAQTE-----------------AP 498
               +          E      +  ++      E+V  Q +                 + 
Sbjct: 421 GWYQTPEGWNGVVYGEGDGIREEDRMLTAEQALEKVIGQLDELVMDGEKRFAPEESSPST 480

Query: 499 KQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFR 558
           + + E+  GFP   SGE+V CDADN+NTDGIYPG YTYQD+V +EKMA+VCM NYD++F 
Sbjct: 481 EAATELYPGFPERVSGEIVFCDADNVNTDGIYPGAYTYQDNVSEEKMAEVCMSNYDSKFS 540

Query: 559 TKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIP 618
           T    GDI+VSGFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P
Sbjct: 541 TIAKEGDILVSGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVP 600

Query: 619 ALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQE 678
            LI +LRE + G  K  TRRTGW L WDV  +++ V EG  +      QKVGEL  N+QE
Sbjct: 601 RLISRLRETFAGDAKVPTRRTGWTLTWDVRKSQIEVQEG--ENGPKWTQKVGELPPNVQE 658

Query: 679 IIVKGGLEGWVKSQL 693
           II KGGLE WVKS +
Sbjct: 659 IIAKGGLEKWVKSAI 673
>ref|NP_593437.1| homoaconitate hydratase Lys2 [Schizosaccharomyces pombe]
 sp|Q9UT74|LYS4_SCHPO Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAB52279.1| homoaconitate hydratase Lys2 [Schizosaccharomyces pombe]
          Length = 721

 Score =  830 bits (2144), Expect = 0.0,   Method: Composition-based stats.
 Identities = 433/687 (63%), Positives = 523/687 (76%), Gaps = 18/687 (2%)

Query: 7   FTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALK 66
            TR F S       Q +TEKIVQ +A N+PE K V SGDYV+IKP HCMSHDNSWPVALK
Sbjct: 49  LTRGFASFNKP--PQTITEKIVQKFAQNIPENKYVRSGDYVTIKPKHCMSHDNSWPVALK 106

Query: 67  FMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIM 126
           FMG+GA K+ +  QIV TLDHD+QNKSE NL KYKNIE+FAK   ID YPAGRGIGHQIM
Sbjct: 107 FMGIGAKKVFDNRQIVCTLDHDVQNKSEANLRKYKNIESFAKGQGIDFYPAGRGIGHQIM 166

Query: 127 IEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKG 186
           +E+GYA P +M VASDSHSNTYGG+G LGTPIVRTDAAAIWATGQTWWQIPP+A+V L G
Sbjct: 167 VEQGYAMPGSMAVASDSHSNTYGGVGCLGTPIVRTDAAAIWATGQTWWQIPPIARVNLVG 226

Query: 187 QLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGL 246
           QLP+G+SGKDIIV+LCG FN+D+VLNHAIEF G+ LN+L I+ RLTIANMTTEWGALSGL
Sbjct: 227 QLPKGLSGKDIIVSLCGAFNHDEVLNHAIEFYGEGLNSLSIESRLTIANMTTEWGALSGL 286

Query: 247 FPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATL 306
           FP D+ L+ WY++RL+ LG N HPR+N +T+ A+  KA    AD+ A YAK LI+DL+TL
Sbjct: 287 FPTDEKLLAWYEDRLKFLGPN-HPRVNRETLDAI--KASPILADEGAFYAKHLILDLSTL 343

Query: 307 THYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNK 366
           +  VSGPNSVKV N+   L ++DI I KAYLVSCTN RLSD+  AA+ V       K  K
Sbjct: 344 SPAVSGPNSVKVYNSAATLEKKDILIKKAYLVSCTNGRLSDIHDAAETV-------KGKK 396

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           VA GVEFYV AASSE+EA A+K+G W+ L+ +G   LP+GCGPCIGLG GLL+ GEVGIS
Sbjct: 397 VADGVEFYVGAASSEVEAAAQKNGDWQTLIDSGARTLPAGCGPCIGLGTGLLKDGEVGIS 456

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPV 486
           ATNRNFKGRMGS++ALAYLASPAVVAASA+ GKI +P    +   +       +I +   
Sbjct: 457 ATNRNFKGRMGSREALAYLASPAVVAASAIAGKIVAPEGFKNAVSL---VSAVDITDKVN 513

Query: 487 VEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMA 546
            +    + TEA      I++GFP   +GE+V CDADN+NTDGIYPG+YTY+DD+ KE+MA
Sbjct: 514 KQTASKSSTEAVDSETAIIDGFPSIVAGEIVFCDADNLNTDGIYPGRYTYRDDITKEEMA 573

Query: 547 QVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRN 606
           +VCMENYD+EF  K    DI+VSGFNFGTGSSREQAATA+L++GI LVV GSF +IF RN
Sbjct: 574 KVCMENYDSEFGKKTKKDDILVSGFNFGTGSSREQAATAILSRGIPLVVGGSFSDIFKRN 633

Query: 607 SINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILE 666
           SINNALL +++P L++KLR  +    KELTRRTGW LKWDV  + V VT         + 
Sbjct: 634 SINNALLAIQLPDLVQKLRTAFANESKELTRRTGWHLKWDVRKSTVTVTTSD---NKEMS 690

Query: 667 QKVGELGKNLQEIIVKGGLEGWVKSQL 693
            K+GELG ++Q + V+GGLEGWVK ++
Sbjct: 691 WKIGELGNSVQSLFVRGGLEGWVKHEI 717
>ref|NP_982841.1| ABL106Cp [Ashbya gossypii ATCC 10895]
 sp|Q75DX9|LYS4_ASHGO Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|AAS50665.1| ABL106Cp [Ashbya gossypii ATCC 10895]
          Length = 686

 Score =  826 bits (2136), Expect = 0.0,   Method: Composition-based stats.
 Identities = 457/692 (66%), Positives = 544/692 (78%), Gaps = 10/692 (1%)

Query: 2   LRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSW 61
           +R     R F +SRA   GQN TEKIVQ++AV L  G  V SGDYVSI+PAHCMSHDNSW
Sbjct: 1   MRVVRCVRRFSASRAV-SGQNTTEKIVQAHAVGLRPGHRVASGDYVSIRPAHCMSHDNSW 59

Query: 62  PVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGI 121
           PVALKFMGLGAT++ +  Q+V TLDHD+QN+SEKNL KY+NIE FA +  +D YPA RGI
Sbjct: 60  PVALKFMGLGATRVHDARQVVCTLDHDVQNRSEKNLAKYRNIELFAAQQGVDFYPARRGI 119

Query: 122 GHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQ 181
           GHQIM+EEGYAFPL +TVASDSHSNTYGG+G+LGTP+VRTDAAAIWATGQTWWQ+PPVA+
Sbjct: 120 GHQIMVEEGYAFPLGLTVASDSHSNTYGGVGALGTPVVRTDAAAIWATGQTWWQVPPVAR 179

Query: 182 VELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWG 241
           VEL G+LP GVSGKD IVALCG+F  D+VLNHA+EF G  +  L ++ RLT+ANMTTEWG
Sbjct: 180 VELTGELPAGVSGKDAIVALCGVFGRDEVLNHAVEFAGPGVARLTVEQRLTVANMTTEWG 239

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLII 301
           ALSGLFPVD  L+DWY+ ++ +     H R+    + AL E+A   + D DA YAK+L +
Sbjct: 240 ALSGLFPVDGVLLDWYREQVARAPAG-HARLTAARVDALAERAAAMQPDTDARYAKQLTL 298

Query: 302 DLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDL 361
           DL++LTHYVSGPNSVKV+  + +L+ Q ++I+KAYL+SCTN RL DL++AA V+   G++
Sbjct: 299 DLSSLTHYVSGPNSVKVARPIAELAPQQLRIDKAYLLSCTNGRLEDLEAAAAVLRADGNV 358

Query: 362 NKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPG 421
               +VAPGVEFY+AAAS+E+EA AR  G W+ LL AGCIPLPSGCGPCIGLG GLLE G
Sbjct: 359 ---RQVAPGVEFYIAAASAEVEAQARARGTWDVLLSAGCIPLPSGCGPCIGLGKGLLEAG 415

Query: 422 EVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEI 481
           EVGISATNRNF+GRMGSKDA AYLASPAVVAASAVLG+I++P EVL  S      V+   
Sbjct: 416 EVGISATNRNFRGRMGSKDAEAYLASPAVVAASAVLGRIAAPCEVLGLSPPAAPAVRAS- 474

Query: 482 IENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVP 541
               V +    A  +    +VE+L GFPR  +GELVLCDADNINTDGIYPGKYTY+DD+P
Sbjct: 475 ----VAQCGAPAAADGAAAAVEVLPGFPRAITGELVLCDADNINTDGIYPGKYTYEDDIP 530

Query: 542 KEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGN 601
           +E MA+VCMENYD +F+  VH GDIVV G+NFGTGSSREQAATALLAKG+ LVV+GSF N
Sbjct: 531 RETMARVCMENYDLDFQHNVHAGDIVVGGYNFGTGSSREQAATALLAKGVPLVVAGSFSN 590

Query: 602 IFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDG 661
            FSRN+INNALLTLE+PAL++ LRE+Y  AP + TRRTG FL WDVA A V VT GS  G
Sbjct: 591 TFSRNAINNALLTLELPALLQLLRERYADAPSQATRRTGVFLTWDVAAATVTVTVGSPTG 650

Query: 662 PVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
             +L Q+VGE   NLQEIIVKGGLEGWVK  L
Sbjct: 651 ERVLHQRVGEFSANLQEIIVKGGLEGWVKHAL 682
>ref|XP_001836222.1| hypothetical protein CC1G_06307 [Coprinopsis cinerea okayama7#130]
 gb|EAU85594.1| hypothetical protein CC1G_06307 [Coprinopsis cinerea okayama7#130]
          Length = 716

 Score =  776 bits (2006), Expect = 0.0,   Method: Composition-based stats.
 Identities = 389/724 (53%), Positives = 487/724 (67%), Gaps = 56/724 (7%)

Query: 8   TRSFHSSRAWLK-GQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALK 66
           TR F++S A  +  Q   EK+VQ YAV LPEGKVV +GDYV IKP H M+HDN+ PV  K
Sbjct: 3   TRRFYASVAAGRVPQTFIEKVVQKYAVGLPEGKVVKAGDYVMIKPEHVMTHDNTGPVISK 62

Query: 67  FMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIM 126
           F  +GATKI NPSQ V TLDHD+QN+S KNL KY NIE FA++H +D YPAGRGIGHQ++
Sbjct: 63  FKSIGATKIHNPSQPVFTLDHDVQNRSSKNLQKYANIEAFARQHGVDFYPAGRGIGHQVL 122

Query: 127 IEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKG 186
           +EEGYAFP  +TVASDSHSN YGG+G +GTPIVRTDAAA+WATG+TWWQ+P + +VELKG
Sbjct: 123 VEEGYAFPHTLTVASDSHSNMYGGVGCVGTPIVRTDAAALWATGKTWWQVPRMVKVELKG 182

Query: 187 QLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGL 246
           +L  GV+GKD+IVALCG FN D+VLN AIEFTG+ ++ L +D RLTIANMTTEWGAL+G+
Sbjct: 183 KLAPGVTGKDVIVALCGSFNKDEVLNAAIEFTGEGVSTLSVDERLTIANMTTEWGALAGV 242

Query: 247 FPVDKTLIDWYKNRLQKL--------------GTNNHPRINPKTIRALEEKAKIPKADKD 292
           FPVD+TL+ WY   L KL                  HPR+N + + AL +      +D  
Sbjct: 243 FPVDETLLSWYDRVLNKLELRTFASPSSSAIPPPPTHPRLNRERLSALRQ--TPLSSDSG 300

Query: 293 AHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAA 352
           A Y+  L+ DL+TL  +VSGPNSVKVS  +  L  Q I INKAYLVSCTNSR+SD+ +AA
Sbjct: 301 AEYSSHLVFDLSTLVPHVSGPNSVKVSTPLPTLESQKIPINKAYLVSCTNSRVSDIAAAA 360

Query: 353 DVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIG 412
            VV       + +K+APGVEFY+AAASS ++ ++   G W+ L++AG   LP+GCGPCIG
Sbjct: 361 AVV-------RGHKIAPGVEFYIAAASSNVQQESEALGDWDALIQAGAKTLPAGCGPCIG 413

Query: 413 LGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEI 472
           LG GLLE GE+GISATNRN+KGRMGS +A AYLASPAVVAASA+ G IS PA +      
Sbjct: 414 LGTGLLEDGEIGISATNRNYKGRMGSPNAQAYLASPAVVAASAINGFISGPASLDPAQLP 473

Query: 473 PFSGVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPG 532
           P       I E P       A    P     +LEGFP  FSG L+    DN+NTDGIYPG
Sbjct: 474 PAGAPTYTISEQPASAASSVAAENEP-----LLEGFPPAFSGPLLFAPQDNLNTDGIYPG 528

Query: 533 KYTYQDDVPKEKMAQVCMENYDAEFR---------------TKVHPGDIVVSGFNFGTGS 577
           KYTYQDD+  E+ A+V MENYD  F                + V PG ++V+G+NFGTGS
Sbjct: 529 KYTYQDDITLERQAEVVMENYDPGFASLVASLRKGFSTSEGSSVKPGVVLVAGYNFGTGS 588

Query: 578 SREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKY--------Q 629
           SREQAATAL + G+ LV++GSFG+IF RN+INN L+ LE P L+  L   Y         
Sbjct: 589 SREQAATALKSAGVPLVIAGSFGDIFKRNAINNGLVCLESPELVADLTAAYTKDGKRGAG 648

Query: 630 GAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWV 689
           G   ELT   G  +  ++ +  V VT     G V    KV  +G ++QE+ + GGLEG++
Sbjct: 649 GKDGELTVDKGLQVVVNMENGNVTVT----TGGVEKVYKVKPVGASVQELWLCGGLEGYI 704

Query: 690 KSQL 693
             ++
Sbjct: 705 LKEI 708
>ref|XP_001880880.1| predicted protein [Laccaria bicolor S238N-H82]
 gb|EDR08655.1| predicted protein [Laccaria bicolor S238N-H82]
          Length = 733

 Score =  764 bits (1974), Expect = 0.0,   Method: Composition-based stats.
 Identities = 379/731 (51%), Positives = 483/731 (66%), Gaps = 58/731 (7%)

Query: 3   RSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWP 62
                  +  S+R+    Q + EK+VQ YAV LPEGK V +GDYV I+P H M+HDN+ P
Sbjct: 15  TQRRCLATIASTRSARVPQTVIEKVVQRYAVGLPEGKAVKAGDYVMIRPEHVMTHDNTGP 74

Query: 63  VALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIG 122
           V  KF  +GAT I NPSQ V TLDHD+QNKS KNL+KY +IE FA+KH ID YPAGRGIG
Sbjct: 75  VITKFNSIGATHIHNPSQPVFTLDHDVQNKSFKNLSKYASIEAFARKHSIDFYPAGRGIG 134

Query: 123 HQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQV 182
           HQ+++EEGYAFP  +TVASDSHSN YGG+G +GTPIVRTDAAA+WATG+TWWQ+P + +V
Sbjct: 135 HQVLVEEGYAFPHTLTVASDSHSNMYGGVGCVGTPIVRTDAAALWATGKTWWQVPRMVKV 194

Query: 183 ELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGA 242
           EL+G+L  GV+GKD+IVALCG FN D+VLN A+EFTG+ +  L +D RLTIANMTTEWGA
Sbjct: 195 ELRGRLKPGVTGKDVIVALCGSFNEDEVLNAALEFTGEGVAGLAVDDRLTIANMTTEWGA 254

Query: 243 LSGLFPVDKTLIDWYKNRLQKL--------------GTNNHPRINPKTIRALEEKAKIPK 288
           L G+FPVD+TL+ WY   L KL                  HPRIN + + AL  +     
Sbjct: 255 LVGVFPVDETLLQWYDRVLAKLELRTFASPSSSAIPPPPVHPRINRQRLDAL--RTANLS 312

Query: 289 ADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDL 348
           +D DA Y+  L+ DL+TL  +VSGPNSVKVS  +  L    I I KAYLVSCTNSR+SD+
Sbjct: 313 SDLDAEYSSHLVFDLSTLVPHVSGPNSVKVSTPLPLLEANKIAIQKAYLVSCTNSRVSDI 372

Query: 349 QSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCG 408
            +AA V+       K  KVAPGV+FY+AAASS ++ ++   G W+ L++AG  PLP+GCG
Sbjct: 373 AAAAAVM-------KGQKVAPGVDFYIAAASSVVQQESETLGDWDALVQAGAKPLPAGCG 425

Query: 409 PCIGLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLS 468
           PCIGLG GLLE G+ GISATNRN+KGRMG   A AYLASPAVVAASA+ G IS PA + S
Sbjct: 426 PCIGLGTGLLEEGQTGISATNRNYKGRMGHPKAQAYLASPAVVAASAINGYISGPASLDS 485

Query: 469 TSEIPFSGVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDG 528
           +                 + +   + +  P  +  +L+GFP  FSG L+    DN+NTDG
Sbjct: 486 SPPAQTPTF--------SISQTSRSASTTPTDAEPLLDGFPAFFSGPLLFAPQDNLNTDG 537

Query: 529 IYPGKYTYQDDVPKEKMAQVCMENYDAEFR----------------TKVHPGDIVVSGFN 572
           IYPGKYTYQDD+  E+ A+V MENYD  F                  +  PG ++V+G+N
Sbjct: 538 IYPGKYTYQDDITLERQAEVVMENYDPGFAVLVSSLRTKLPSPSPDAETKPGVVLVAGYN 597

Query: 573 FGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQ--- 629
           FGTGSSREQAATAL A GI LV++GSFG+IF RN+INN L+ LE P L++ L E Y    
Sbjct: 598 FGTGSSREQAATALKAAGIPLVIAGSFGDIFKRNAINNGLVCLESPELVQDLTEAYAKDG 657

Query: 630 -----GAPKELTRRTGWFLKWDVADAKVVV--TEGSLDGPVILEQKVGELGKNLQEIIVK 682
                G   ELT   G  ++  + D +V V  +  S +G V     V  +G ++QE+ + 
Sbjct: 658 RRGAGGKQGELTVDKGLNVEVGMVDGRVYVRSSVSSAEGNVKTYH-VKPVGPSVQELWLC 716

Query: 683 GGLEGWVKSQL 693
           GGLEG++  ++
Sbjct: 717 GGLEGYILKEI 727
>ref|XP_567622.1| homoaconitate hydratase [Cryptococcus neoformans var. neoformans
           JEC21]
 sp|Q5K9V9|LYS4_CRYNE Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|AAW46105.1| homoaconitate hydratase, putative [Cryptococcus neoformans var.
           neoformans JEC21]
          Length = 728

 Score =  764 bits (1973), Expect = 0.0,   Method: Composition-based stats.
 Identities = 375/720 (52%), Positives = 465/720 (64%), Gaps = 49/720 (6%)

Query: 10  SFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMG 69
            F+++      Q L EKIVQ YAV L EG  V +GDYV IKP H M+HDN+ PV  KF+ 
Sbjct: 22  RFYAT--VSTPQTLVEKIVQKYAVGLSEGVKVRAGDYVMIKPEHVMTHDNTGPVISKFLS 79

Query: 70  LGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEE 129
           L  +K+ NP Q V  LDHD+QN+SE N  KYK I+ FAK+H +D YPAGRGIGHQI++EE
Sbjct: 80  LSCSKLDNPRQPVFALDHDVQNQSETNQKKYKKIQAFAKEHGVDFYPAGRGIGHQIIVEE 139

Query: 130 GYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLP 189
           GYA+P  M VASDSHSN YGG+G LGT IVRTDAA IWATG+ WWQIP +  V L G+L 
Sbjct: 140 GYAWPGKMVVASDSHSNHYGGVGCLGTAIVRTDAAGIWATGKFWWQIPRIVSVSLDGRLS 199

Query: 190 QGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPV 249
            GV+GKD+IVAL GLFN D+VLN AIEFTG  +  L ID RLTIANMTTEWGA++G+FPV
Sbjct: 200 PGVTGKDVIVALAGLFNKDEVLNAAIEFTGSGVEHLSIDERLTIANMTTEWGAVAGVFPV 259

Query: 250 DKTLIDWYKNRLQKLGTNNH----------PRINPKTIRALEEKAKIPK--ADKDAHYAK 297
           D  L +WY+  L+K                 +++P+   A  + A   +  AD  AHYA 
Sbjct: 260 DDKLKEWYQGILRKAELRKFISPTVPSTVGAKVHPRLNAARLDDAMTNRVVADPGAHYAA 319

Query: 298 KLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCP 357
           +L +DL+TL  +VSGPNSVKV+  +  L    I INKAYLVSCTNSR SD+ SAA V+  
Sbjct: 320 RLSLDLSTLVPHVSGPNSVKVATALPKLLDPPIPINKAYLVSCTNSRASDIASAAQVL-- 377

Query: 358 TGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGL 417
                +  KVAPGVEFY+AAASS ++ DA  +G W+ L+ AG   LP+GCGPCIGLG GL
Sbjct: 378 -----RGKKVAPGVEFYIAAASSRVQEDAEAAGDWQTLIDAGAKTLPAGCGPCIGLGVGL 432

Query: 418 LEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGV 477
           LE GEVGISATNRN+KGRMGS DA+AYLASPAVVAASA  G I  P  +  +    +   
Sbjct: 433 LEKGEVGISATNRNYKGRMGSPDAIAYLASPAVVAASAAKGVICGPESMDLSQLPQYEQP 492

Query: 478 KTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQ 537
           K  IIE     EE   + +       +LEGFP  F G L+    DN+ TDG+YPGKYTYQ
Sbjct: 493 KFSIIEEGAAGEEKPVEVDEASLE-PLLEGFPAYFEGPLLFAPQDNLTTDGMYPGKYTYQ 551

Query: 538 DDVPKEKMAQVCMENYDAEFRTKVH---------------PGDIVVSGFNFGTGSSREQA 582
           DD+  E+ A+V MENYD  F                    PG I++SG+NFGTGSSREQA
Sbjct: 552 DDITPERQAEVVMENYDPTFAATARELRTALPTASSPSTLPGAILLSGYNFGTGSSREQA 611

Query: 583 ATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQ--------GAPKE 634
           ATA+   GI LV+ GSFG+IF RNSINN L+ +E P+LIK + E++         G   +
Sbjct: 612 ATAIKNAGIPLVICGSFGDIFKRNSINNGLILIESPSLIKDMTERFAKDGVRNKGGKDGK 671

Query: 635 LTRRT-GWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           LT    GW +K D     V V  G  +       KVG   +++QE+ V GGLEG++++ L
Sbjct: 672 LTVVPEGWRIKVDSQRGLVTVNMGEEEEKTYPAAKVG---RSVQELWVNGGLEGFIRASL 728
>ref|XP_772920.1| hypothetical protein CNBK2910 [Cryptococcus neoformans var.
           neoformans B-3501A]
 gb|EAL18273.1| hypothetical protein CNBK2910 [Cryptococcus neoformans var.
           neoformans B-3501A]
          Length = 728

 Score =  762 bits (1969), Expect = 0.0,   Method: Composition-based stats.
 Identities = 374/720 (51%), Positives = 465/720 (64%), Gaps = 49/720 (6%)

Query: 10  SFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMG 69
            F+++      Q L EKIVQ YAV L EG  V +GDYV IKP H M+HDN+ PV  KF+ 
Sbjct: 22  RFYAT--VSTPQTLVEKIVQKYAVGLSEGVKVRAGDYVMIKPEHVMTHDNTGPVISKFLS 79

Query: 70  LGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEE 129
           L  +K+ NP Q V  LDHD+QN+SE N  KYK I+ FAK+H +D YPAGRGIGHQI++EE
Sbjct: 80  LSCSKLDNPRQPVFALDHDVQNQSETNQKKYKKIQAFAKEHGVDFYPAGRGIGHQIIVEE 139

Query: 130 GYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLP 189
           GYA+P  M VASDSHSN YGG+G LGT IVRTDAA IWATG+ WWQIP +  V L G+L 
Sbjct: 140 GYAWPGKMVVASDSHSNHYGGVGCLGTAIVRTDAAGIWATGKFWWQIPRIVSVSLDGRLS 199

Query: 190 QGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPV 249
            GV+GKD+IVAL GLFN D+VLN AIEFTG  +  L ID RLTIANMTTEWGA++G+FPV
Sbjct: 200 PGVTGKDVIVALAGLFNKDEVLNAAIEFTGSGVEHLSIDERLTIANMTTEWGAVAGVFPV 259

Query: 250 DKTLIDWYKNRLQKLGTNNH----------PRINPKTIRALEEKAKIPK--ADKDAHYAK 297
           D  L +WY+  L+K                 +++P+   A  + A   +  AD  AHYA 
Sbjct: 260 DDKLKEWYQGILRKAELRKFISPTVPSTVGAKVHPRLNAARLDDAMTNRVVADPGAHYAA 319

Query: 298 KLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCP 357
           +L +DL+TL  +VSGPNSVKV+  +  L    I INKAYLVSCTNSR SD+ SAA V+  
Sbjct: 320 RLSLDLSTLVPHVSGPNSVKVATALPKLLDPPIPINKAYLVSCTNSRASDIASAAQVL-- 377

Query: 358 TGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGL 417
                +  KVAPGVEFY+AAASS ++ DA  +G W+ L+ AG   LP+GCGPCIGLG GL
Sbjct: 378 -----RGKKVAPGVEFYIAAASSRVQEDAEAAGDWQTLIDAGAKTLPAGCGPCIGLGVGL 432

Query: 418 LEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGV 477
           LE GEVGISATNRN+KGRMGS DA+AYLASPAVVAASA  G I  P  +  +    +   
Sbjct: 433 LEKGEVGISATNRNYKGRMGSPDAIAYLASPAVVAASAAKGVICGPESMDLSQLPQYEQP 492

Query: 478 KTEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQ 537
           K  II+     EE   + +       +LEGFP  F G L+    DN+ TDG+YPGKYTYQ
Sbjct: 493 KFSIIKEGAAGEEKPVEVDEASLE-PLLEGFPAYFEGPLLFAPQDNLTTDGMYPGKYTYQ 551

Query: 538 DDVPKEKMAQVCMENYDAEFRTKVH---------------PGDIVVSGFNFGTGSSREQA 582
           DD+  E+ A+V MENYD  F                    PG I++SG+NFGTGSSREQA
Sbjct: 552 DDITPERQAEVVMENYDPTFAATARELRTALPTASSPSTLPGAILLSGYNFGTGSSREQA 611

Query: 583 ATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQ--------GAPKE 634
           ATA+   GI LV+ GSFG+IF RNSINN L+ +E P+LIK + E++         G   +
Sbjct: 612 ATAIKNAGIPLVICGSFGDIFKRNSINNGLILIESPSLIKDMTERFAKDGVRNKGGKDGK 671

Query: 635 LTRRT-GWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           LT    GW +K D     V V  G  +       KVG   +++QE+ V GGLEG++++ L
Sbjct: 672 LTVVPEGWRIKVDSQRGLVTVNMGEEEEKTYPAAKVG---RSVQELWVNGGLEGFIRASL 728
>ref|NP_622150.1| aconitate hydratase [Thermoanaerobacter tengcongensis MB4]
 gb|AAM23754.1| Aconitase A [Thermoanaerobacter tengcongensis MB4]
          Length = 641

 Score =  754 bits (1948), Expect = 0.0,   Method: Composition-based stats.
 Identities = 194/705 (27%), Positives = 320/705 (45%), Gaps = 101/705 (14%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA-LKFMGLGATKIKNPS 79
            NLT+KI+ ++ V   EGK+   G+ ++IK    ++ D++  +A L+   LG  ++K   
Sbjct: 1   MNLTQKILLAHLV---EGKMAK-GEEIAIKIDQTLTQDSTGTMAYLQLEALGIDRVKT-E 55

Query: 80  QIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTV 139
             V+ +DH+   +  +N   +K ++  A ++ I     G GI HQ+ +E  +  P    +
Sbjct: 56  LSVSYVDHNTLQQGPENADDHKYLQTVAARYGIYFSRPGNGICHQVHLER-FGVPGKTLL 114

Query: 140 ASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIV 199
            SDSH+ T GGLG L       D A   A       +P +  V LKG+L   VS KD+I+
Sbjct: 115 GSDSHTPTAGGLGMLAIGAGGLDVALAMAGEPYRIIMPAIVNVRLKGELNPWVSAKDVIL 174

Query: 200 ALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKN 259
            L         +    E++GD +  L +  R TIANM  E GA + +FP D+   ++ K 
Sbjct: 175 ELLRRLTVKGGIGKIFEYSGDGVKTLSVPERTTIANMGAELGATTSIFPSDERTYEFLKA 234

Query: 260 RLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVS 319
           + +                  E+      AD+DA Y + + IDL+ L   V+ P+S    
Sbjct: 235 QGR------------------EDVFVPLSADEDAEYDEVIEIDLSELEPMVALPHSPDNV 276

Query: 320 NTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAAS 379
             V+D  +   ++++  + SCTNS   DL   A ++       K   +   V   +A  S
Sbjct: 277 VKVKDAGRP--RVDQVAIGSCTNSSYMDLMKVASIL-------KGKTIPEHVSLVIAPGS 327

Query: 380 SEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSK 439
            ++     K+GA   L+ AG   L S CGPCIG+G      G V +   NRNF GR G+K
Sbjct: 328 RQVLTMLAKNGALADLIAAGARILESACGPCIGMGQA-PATGAVSVRTFNRNFYGRSGTK 386

Query: 440 DALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEAPK 499
            A  YL SP V AA+A+ G +  P E+    ++P       ++E   V + +  +     
Sbjct: 387 SAYVYLVSPEVAAAAALTGYLIDPRELGEPPQVP-------LVERFEVNDNMIVKPPEDG 439

Query: 500 QSVEI-----LEGFP-----REFSGELVLCDADNINTDGIYPGK---YTYQDDVPKEKMA 546
           ++VE+     ++ FP      +   ++++   D+I TD I P        + ++P+  ++
Sbjct: 440 KNVEVIKGPNIKPFPLNTPLSDIEKKVLIKVGDDITTDHIMPSNARLLPLRSNIPE--LS 497

Query: 547 QVCMENYDAEFRTKVHP--GDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFS 604
           + C E  D  F  +     G I+V G N+G GSSRE AA   L  G+  V++ SF  I  
Sbjct: 498 KHCFEIIDENFSKRAVEWGGGIIVGGHNYGQGSSREHAALVPLYLGVKAVIAKSFARIHK 557

Query: 605 RNSINNALLTLE-----------------IPALIKKLREKYQGAPKELTRRTGWFLKWDV 647
            N IN+ +L L                  I   ++++R       K LT+   + ++ +V
Sbjct: 558 ANLINSGILPLTFVKEEDYEDIDMGDVLKIENTVEQVRSGKNIIVKNLTKGKSFEVRLEV 617

Query: 648 ADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
           +D                           +EI++ GG+  +VKS+
Sbjct: 618 SDRN-------------------------REILIAGGMINYVKSK 637
>ref|YP_001665791.1| putative aconitate hydratase [Thermoanaerobacter pseudethanolicus
           ATCC 33223]
 ref|YP_001662062.1| putative aconitate hydratase [Thermoanaerobacter sp. X514]
 gb|ABY91726.1| putative aconitate hydratase [Thermoanaerobacter sp. X514]
 gb|ABY95455.1| putative aconitate hydratase [Thermoanaerobacter pseudethanolicus
           ATCC 33223]
          Length = 639

 Score =  752 bits (1943), Expect = 0.0,   Method: Composition-based stats.
 Identities = 197/703 (28%), Positives = 314/703 (44%), Gaps = 97/703 (13%)

Query: 21  QNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA-LKFMGLGATKIKNPS 79
            NLT+KI+ S+ +   EG++V  G  ++IK    ++ D++  +A L+   LG  ++K   
Sbjct: 1   MNLTQKILSSHLI---EGEMVK-GQEIAIKIDQTLTQDSTGTMAYLQLEALGIDRVKT-E 55

Query: 80  QIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTV 139
             V  +DH+   +  +N   +K I+  A K+ I     G GI HQ+ +E  +  P    +
Sbjct: 56  LSVAYIDHNTLQQGPENADDHKYIQTVAAKYGIYFSRPGNGICHQVHLER-FGRPGKTLL 114

Query: 140 ASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIV 199
            SDSH+ T GGLG L       D A   A       +P +  V L G+L   VS KD+I+
Sbjct: 115 GSDSHTPTAGGLGMLAIGAGGLDVALAMAGEPYRIIMPSIVNVRLTGKLRPWVSAKDVIL 174

Query: 200 ALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKN 259
            L         +    E++GD +  L +  R TIANM  E GA + +FP D+   ++ K 
Sbjct: 175 ELLRRLTVKGGVGKIFEYSGDGVKTLSVPERATIANMGAELGATTSIFPSDERTYEFLKA 234

Query: 260 RLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVS 319
           + +                  EE      AD+DA Y + + I+L  L   V+ P+S    
Sbjct: 235 QGR------------------EEVFVPLAADEDAEYDEVIEINLDELEPLVALPHSPDNV 276

Query: 320 NTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAAS 379
             V+D  +   K+++  + SCTNS  +DL   A ++       +   +   V   +A  S
Sbjct: 277 VKVKDAGRP--KVDQVAIGSCTNSSYADLMKVASIL-------RGKVILEHVSLVIAPGS 327

Query: 380 SEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSK 439
            ++     K+GA   L+ AG   L S CGPCIG+G      G + I   NRNF GR G+K
Sbjct: 328 RQVLNMLAKNGALSDLISAGARILESACGPCIGMGQA-PATGAISIRTFNRNFYGRSGTK 386

Query: 440 DALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFS---GVKTEIIENPVVEEEVNAQTE 496
            A  YL SP V AA+A+ G +  P E+    E+P+     +   +I  P  + E     +
Sbjct: 387 SASVYLVSPEVAAAAALTGYLIDPRELGEAPEVPYVEKFEINDNMIIKPPEDREKVEIIK 446

Query: 497 APKQSVEILEGFP-----REFSGELVLCDADNINTDGIYPGK---YTYQDDVPKEKMAQV 548
            P      ++ FP      +    +++   D+I TD I P        + ++P+  +A+ 
Sbjct: 447 GPN-----IKPFPLNTPLSDIEKRVLIKVGDDITTDHIMPSNAKLLPLRSNIPE--LAKH 499

Query: 549 CMENYDAEFRTKVHP--GDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRN 606
           C E  D  F  +     G I+V G N+G GSSRE AA A L  G+  V++ SF  I   N
Sbjct: 500 CFEIIDENFSKRAIEWGGGIIVGGSNYGQGSSREHAALAPLQLGVKAVIAKSFARIHKAN 559

Query: 607 SINNALLTLE-----------------IPALIKKLREKYQGAPKELTRRTGWFLKWDVAD 649
            IN+ +L L                  I   ++++R   +     +T+   + +  DV+D
Sbjct: 560 LINSGILPLTFVDEKDYEDIEVGDVLKIENAVEQVRSGKKIIIVNVTKGKTFEVTLDVSD 619

Query: 650 AKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
                                      +EI++ GG+  +VKS+
Sbjct: 620 RN-------------------------REILIAGGMINFVKSK 637
>ref|YP_001039546.1| aconitate hydratase [Clostridium thermocellum ATCC 27405]
 gb|ABN54353.1| aconitase [Clostridium thermocellum ATCC 27405]
          Length = 642

 Score =  751 bits (1941), Expect = 0.0,   Method: Composition-based stats.
 Identities = 192/697 (27%), Positives = 317/697 (45%), Gaps = 80/697 (11%)

Query: 19  KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA-LKFMGLGATKIKN 77
            G NL +KI++ + V+      +  G  ++I+    ++ D++  +A L+F  +G  ++K 
Sbjct: 1   MGLNLAQKIIKEHLVSGE----MKPGTEIAIRIDQTLTQDSTGTMAYLQFEAMGIPRVKT 56

Query: 78  PSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNM 137
             + V  +DH+      +N   +K I+  A KH I     G GI HQ+ +E  +  P   
Sbjct: 57  K-KSVAYIDHNTLQTGFENADDHKYIQTVAAKHGIYFSKPGNGICHQVHLER-FGVPGMT 114

Query: 138 TVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDI 197
            + SDSH+ T GG+G L       D A     G  +  +P V +V LKG L   V+ KDI
Sbjct: 115 LLGSDSHTPTGGGIGMLAIGAGGLDVAVAMGGGPYYMMMPKVCRVVLKGALKPWVTAKDI 174

Query: 198 IVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWY 257
           I+ +    +    +   IE+ GD +  L +  R TI NM  E GA + +FP D+   ++ 
Sbjct: 175 ILEVLRRLSVKGGVGKIIEYAGDGIKTLTVPERATITNMGAELGATTSIFPSDEVTREFL 234

Query: 258 KNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
           + + +                  E      K D+DA Y ++++I+L  L    + P+S  
Sbjct: 235 RAQGR------------------ENDWVELKPDEDAEYDEEIVINLDELEPLAAQPHSPD 276

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAA 377
               V+D+ +  IK+++  + SCTNS   D+   A ++       K  KV P V   +A 
Sbjct: 277 NVAKVKDIGK--IKVDQVAIGSCTNSSYMDMMKVAAIL-------KGKKVHPDVSLVIAP 327

Query: 378 ASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMG 437
            S ++     ++GA   ++ AG   L S CGPCIG+G        V +   NRNF+GR G
Sbjct: 328 GSKQVLTMLAQNGALADMVAAGARILESACGPCIGMGQA-PATDAVSLRTFNRNFEGRSG 386

Query: 438 SKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEA 497
           +K A  YL SP   AASA+ G +  P E+           K  + E  V+++ +      
Sbjct: 387 TKSAKVYLVSPETAAASAITGVLIDPRELGEAP-------KVSMPEKFVIDDSMVLPPAP 439

Query: 498 PKQSVEI-----LEGFP------REFSGELVLCDADNINTDGIYPGK---YTYQDDVPKE 543
               VE+     ++ FP       + SG+ ++   DNI TD I P       ++ +VP  
Sbjct: 440 EGAEVEVVRGPNIKPFPINQALADKVSGKALIKVGDNITTDHIMPSNAKLLPFRSNVPY- 498

Query: 544 KMAQVCMENYDAEF--RTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGN 601
            +A+ C+   D +F  R K + G  ++ G N+G GSSRE AA A L  G+  V++ SF  
Sbjct: 499 -LAEFCLTPCDPDFPKRAKENGGGFIIGGSNYGQGSSREHAALAPLQLGVKGVIAKSFAR 557

Query: 602 IFSRNSINNALLTL--EIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVV----VT 655
           I   N IN+ ++ +  E  A   ++                  L  + A  ++     + 
Sbjct: 558 IHMANLINSGIIPMTFENEADYDEIDMD-------------DELVIENAREQIKNGSSIV 604

Query: 656 EGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
             ++     ++  V  L +   EII+ GGL  + + Q
Sbjct: 605 VKNVTKGKDIKVNV-ALSQRQVEIILAGGLLNYTRQQ 640
>ref|YP_002802745.1| aconitase/isopropylmalate dehydratase family protein [Clostridium
           botulinum A2 str. Kyoto]
 gb|ACO86147.1| aconitase/isopropylmalate dehydratase family protein [Clostridium
           botulinum A2 str. Kyoto]
          Length = 641

 Score =  751 bits (1941), Expect = 0.0,   Method: Composition-based stats.
 Identities = 209/690 (30%), Positives = 323/690 (46%), Gaps = 69/690 (10%)

Query: 19  KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA-LKFMGLGATKIKN 77
            G  LTEKI++S+ V   +G +   G+ ++IK  + ++ D++  +A L+F  LG  K+K 
Sbjct: 1   MGLTLTEKIIKSHLV---KGNMTK-GEEIAIKIDNTLTQDSTGTMAYLQFEALGIDKVKT 56

Query: 78  PSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNM 137
             + V  +DH++     +N   +  I+  AKKH I     G GI HQ+ +E  +  P   
Sbjct: 57  K-RSVAYIDHNMLQSGPENADDHLYIQTVAKKHGIYFSKPGNGICHQVNLER-FGVPGET 114

Query: 138 TVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDI 197
            + SDSH+ T GG+G L       D A   A G+ +  +P V +V L G+L   VS KDI
Sbjct: 115 LLGSDSHTPTGGGIGMLAIGAGGLDVAVAMAGGEYYINMPKVVKVNLIGKLKPFVSAKDI 174

Query: 198 IVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWY 257
           I+ +    +    +    E+TG+ + AL +  R TI NM  E GA + +FP D+   D+ 
Sbjct: 175 ILEVLRRLSVKGGVGKIFEYTGEGVKALTVPERATITNMGAELGATTSIFPSDEITKDFL 234

Query: 258 KNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
           K + +                  EE  K   AD+DA Y ++L I+L+ L    + P+S  
Sbjct: 235 KAQER------------------EEDYKYLVADEDAVYDEELEINLSDLKPLAACPHSPD 276

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAA 377
               V +L  ++IK+N+  + SCTNS   D+   A ++       K   V+  V   +A 
Sbjct: 277 NIVPVSEL--KNIKVNQVAIGSCTNSSYRDMLRTASIL-------KGKTVSENVSLVIAP 327

Query: 378 ASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMG 437
            S ++      +GA   L+ AG   L   CGPCIG+G        V +   NRNF+GR G
Sbjct: 328 GSKQVLNMMANNGALTDLVMAGARILECACGPCIGMGQSPCTD-AVSLRTFNRNFEGRSG 386

Query: 438 SKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSG---VKTEIIENPVVEEEVNAQ 494
           +K A  YL SP V A SA+ G I+ P E+    +I       +   +I  P  E EV   
Sbjct: 387 TKSANVYLVSPEVAAVSALTGYITDPTELTDFEDIEMPNKFLINDNLIIEPATEGEVVDV 446

Query: 495 TEAPKQSVEILEGFPRE------FSGELVLCDADNINTDGIYPGK---YTYQDDVPKEKM 545
              P      ++ FP+        +G+ +    DNI TD I P       Y+ +VP   +
Sbjct: 447 KRGPN-----IKPFPKAEALKELVTGKALTKVGDNITTDHIMPSNAKLLPYRSNVPY--L 499

Query: 546 AQVCMENYDAEF--RTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIF 603
           +  C+   D EF  + K + G I+V+G N+G GSSRE AA A +  GI  V++ SF  I 
Sbjct: 500 SNFCLTPCDEEFPEKAKENGGGIIVAGTNYGQGSSREHAALAPVYLGIKAVLAKSFARIH 559

Query: 604 SRNSINNALLTLEIPA--LIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDG 661
             N INN +L L          + E  +   + +  +     K D+ +    +   +L  
Sbjct: 560 KANLINNGILPLVFEREEDYDSIDEMDELVIENVLNQVE-IGKIDIINKTKGIKYKTLLE 618

Query: 662 PVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
               ++K          +I+KGGL   +KS
Sbjct: 619 ATERQKK----------MILKGGLLNLIKS 638
>ref|NP_214222.1| aconitate hydratase [Aquifex aeolicus VF5]
 gb|AAC07617.1| aconitase [Aquifex aeolicus VF5]
          Length = 659

 Score =  751 bits (1941), Expect = 0.0,   Method: Composition-based stats.
 Identities = 188/696 (27%), Positives = 309/696 (44%), Gaps = 73/696 (10%)

Query: 22  NLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA-LKFMGLGATKIKNPSQ 80
            +  KI++++ V    GK+   G+ ++IK    ++ D +  +  L+F  +G  ++K    
Sbjct: 5   TVAWKIIKNHLV---SGKM-EPGEEIAIKIDQTLTQDATGTMCYLEFEAMGVPEVKT-EL 59

Query: 81  IVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVA 140
            V+ +DH++     +N   +K + + AKK  I     G GI HQ+ +E  +A P    + 
Sbjct: 60  SVSYIDHNMLQTDFRNADDHKYLMSVAKKFGIWLSKPGNGICHQVHLER-FAKPGKTLLG 118

Query: 141 SDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIVA 200
           SDSH+ T GG+G L       D AA  A    + ++P +  V LKG++P+ V+ KDII+ 
Sbjct: 119 SDSHTPTAGGMGMLAIGAGGLDVAAAMAGEPFYLKMPKIVGVHLKGKMPEWVTAKDIILE 178

Query: 201 LCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWYKNR 260
           L         L    E+ G+ +  L +  R TI NM  E GA + +FP D+    + + +
Sbjct: 179 LLRRLTVKGGLGKIFEYFGEGVKELSVPERATITNMGAELGATTSIFPSDEITRAYLRAQ 238

Query: 261 LQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVKVSN 320
            +                  EE       D DA Y + + I+L+ L   ++ P+S     
Sbjct: 239 GR------------------EEDWVELLPDPDAEYDEVIEINLSELEPLIAQPHSPDNVV 280

Query: 321 TVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASS 380
            V+++  + IK+++  + SCTNS   DL  AA ++       +  +V P V F VA  S 
Sbjct: 281 PVREI--EGIKVDQVVIGSCTNSSFVDLTRAAKLL-------EGRRVHPDVVFAVAPGSK 331

Query: 381 EIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMGSKD 440
           +      ++GA    LKAG   L S CGPCIG+G      G V + + NRNFKGR G+ D
Sbjct: 332 QALELITQNGALLNFLKAGARILESACGPCIGMGFAPPTNG-VSVRSFNRNFKGRAGTPD 390

Query: 441 ALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVEEEVNAQTEAPKQ 500
           A  YLASP    A+A+ G+I  P ++     + +  ++ E+ E     +E        ++
Sbjct: 391 AKVYLASPETCVAAAIAGEIIDPRKLAEREGVKW--IRVEMPEKFPYGDEAFIPPLPKEE 448

Query: 501 S-------------VEILEGFPREFSGELVLCDADNINTDGIYPGK---YTYQDDVPKEK 544
                         +   E  P    GE+ L   DNI TD I P        + ++    
Sbjct: 449 REKVEIYRGPNIKPLPEFEPLPETIEGEVALIVEDNITTDHIMPAGAKILPLRSNI--YA 506

Query: 545 MAQVCMENYDAEFRTKVH------PGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGS 598
           +++      D EF  ++          I++ G N+G GSSRE AA A    G+  V++ S
Sbjct: 507 ISEYVYHYVDPEFVPRMKKLKEKGKAGIIIGGENYGQGSSREHAALAPRFLGVRAVIAKS 566

Query: 599 FGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTE 656
           F  I   N +N  ++ LE        K     +     L  R        +   + ++  
Sbjct: 567 FARIHHANLVNFGVVPLEFKNKEDYDKFSLGDEIEIPNLIER--------LKKGEDILVI 618

Query: 657 GSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
               G  IL      L    +EI++ GG   ++K++
Sbjct: 619 NKTTGEEILC--TYNLTPVQKEILIAGGRLNYIKNK 652
>ref|YP_001389789.1| aconitase/isopropylmalate dehydratase family protein [Clostridium
           botulinum F str. Langeland]
 gb|ABS39722.1| aconitase/isopropylmalate dehydratase family protein [Clostridium
           botulinum F str. Langeland]
          Length = 641

 Score =  751 bits (1940), Expect = 0.0,   Method: Composition-based stats.
 Identities = 209/690 (30%), Positives = 323/690 (46%), Gaps = 69/690 (10%)

Query: 19  KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA-LKFMGLGATKIKN 77
            G  LTEKI++S+ V   +G +   G+ ++IK  + ++ D++  +A L+F  LG  K+K 
Sbjct: 1   MGLTLTEKIIKSHLV---KGNMTK-GEEIAIKIDNTLTQDSTGTMAYLQFEALGIDKVKT 56

Query: 78  PSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNM 137
             + V  +DH++     +N   +  I+  AKKH I     G GI HQ+ +E  +  P   
Sbjct: 57  K-RSVAYIDHNMLQSGPENADDHLYIQTVAKKHGIYFSKPGNGICHQVNLER-FGVPGET 114

Query: 138 TVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDI 197
            + SDSH+ T GG+G L       D A   A G+ +  +P V +V L G+L   VS KDI
Sbjct: 115 LLGSDSHTPTGGGIGMLAIGAGGLDVAVAMAGGEYYINMPKVVKVNLIGKLKPFVSAKDI 174

Query: 198 IVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWY 257
           I+ +    +    +    E+TG+ + AL +  R TI NM  E GA + +FP D+   D+ 
Sbjct: 175 ILEVLRRLSVKGGVGKIFEYTGEGVKALTVPERATITNMGAELGATTSIFPSDEITKDFL 234

Query: 258 KNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
           K + +                  EE  K   AD+DA Y ++L I+L+ L    + P+S  
Sbjct: 235 KAQER------------------EEDYKYLVADEDAVYDEELEINLSELKPLAACPHSPD 276

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAA 377
               V +L  ++IK+N+  + SCTNS   D+   A ++       K   V+  V   +A 
Sbjct: 277 NIVPVSEL--KNIKVNQVAIGSCTNSSYRDMLRTASIL-------KGKTVSENVSLVIAP 327

Query: 378 ASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMG 437
            S ++      +GA   L+ AG   L   CGPCIG+G        V +   NRNF+GR G
Sbjct: 328 GSKQVLNMMANNGALTDLVMAGARILECACGPCIGMGQSPCTD-AVSLRTFNRNFEGRSG 386

Query: 438 SKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSG---VKTEIIENPVVEEEVNAQ 494
           +K A  YL SP V A SA+ G I+ P E+    +I       +   +I  P  E EV   
Sbjct: 387 TKSANVYLVSPEVAAVSALTGYITDPTELTDFEDIEMPNKFLINDNLIIEPATEGEVVEV 446

Query: 495 TEAPKQSVEILEGFPRE------FSGELVLCDADNINTDGIYPGK---YTYQDDVPKEKM 545
              P      ++ FP+        +G+ +    DNI TD I P       Y+ +VP   +
Sbjct: 447 KRGPN-----IKPFPKAEALKELVTGKALTKVGDNITTDHIMPSNAKLLPYRSNVPY--L 499

Query: 546 AQVCMENYDAEF--RTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIF 603
           +  C+   D EF  + K + G I+V+G N+G GSSRE AA A +  GI  V++ SF  I 
Sbjct: 500 SNFCLTPCDEEFPEKAKENGGGIIVAGTNYGQGSSREHAALAPVYLGIKAVLAKSFARIH 559

Query: 604 SRNSINNALLTLEIPA--LIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDG 661
             N INN +L L          + E  +   + +  +     K D+ +    +   +L  
Sbjct: 560 KANLINNGILPLVFEREEDYDSIDEMDELVIENVLNQVE-IGKIDIINKTKGIKYKTLLE 618

Query: 662 PVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
               ++K          +I+KGGL   +KS
Sbjct: 619 ATDRQKK----------MILKGGLLNLIKS 638
>ref|YP_001780072.1| aconitase/isopropylmalate dehydratase family protein [Clostridium
           botulinum B1 str. Okra]
 gb|ACA45426.1| aconitase/isopropylmalate dehydratase family protein [Clostridium
           botulinum B1 str. Okra]
          Length = 641

 Score =  751 bits (1940), Expect = 0.0,   Method: Composition-based stats.
 Identities = 209/690 (30%), Positives = 323/690 (46%), Gaps = 69/690 (10%)

Query: 19  KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA-LKFMGLGATKIKN 77
            G  LTEKI++S+ V   +G +   G+ ++IK  + ++ D++  +A L+F  LG  K+K 
Sbjct: 1   MGLTLTEKIIKSHLV---KGNMTK-GEEIAIKIDNTLTQDSTGTMAYLQFEALGIDKVKT 56

Query: 78  PSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNM 137
             + V  +DH++     +N   +  I+  AKKH I     G GI HQ+ +E  +  P   
Sbjct: 57  K-RSVAYIDHNMLQSGPENADDHLYIQTVAKKHGIYFSKPGNGICHQVNLER-FGVPGET 114

Query: 138 TVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDI 197
            + SDSH+ T GG+G L       D A   A G+ +  +P V +V L G+L   VS KDI
Sbjct: 115 LLGSDSHTPTGGGIGMLAIGAGGLDVAVAMAGGEYYINMPKVVKVNLIGKLKPFVSAKDI 174

Query: 198 IVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWY 257
           I+ +    +    +    E+TG+ + AL +  R TI NM  E GA + +FP D+   D+ 
Sbjct: 175 ILEVLRRLSVKGGVGKIFEYTGEGVKALTVPERATITNMGAELGATTSIFPSDEITKDFL 234

Query: 258 KNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTHYVSGPNSVK 317
           K + +                  EE  K   AD+DA Y ++L I+L+ L    + P+S  
Sbjct: 235 KAQER------------------EEDYKYLVADEDAVYDEELEINLSDLKPLAACPHSPD 276

Query: 318 VSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAA 377
               V +L  ++IK+N+  + SCTNS   D+   A ++       K   V+  V   +A 
Sbjct: 277 NIVPVSEL--KNIKVNQVAIGSCTNSSYRDMLRTASIL-------KGKTVSENVSLVIAP 327

Query: 378 ASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISATNRNFKGRMG 437
            S ++      +GA   L+ AG   L   CGPCIG+G        V +   NRNF+GR G
Sbjct: 328 GSKQVLNMMANNGALTDLVMAGARILECACGPCIGMGQSPCTD-AVSLRTFNRNFEGRSG 386

Query: 438 SKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSG---VKTEIIENPVVEEEVNAQ 494
           +K A  YL SP V A SA+ G I+ P E+    +I       +   +I  P  E EV   
Sbjct: 387 TKSANVYLVSPEVAAVSALTGYITDPTELTDFEDIEMPNKFLINDNLIIEPATEGEVVEV 446

Query: 495 TEAPKQSVEILEGFPRE------FSGELVLCDADNINTDGIYPGK---YTYQDDVPKEKM 545
              P      ++ FP+        +G+ +    DNI TD I P       Y+ +VP   +
Sbjct: 447 KRGPN-----IKPFPKAEALKELVTGKALTKVGDNITTDHIMPSNAKLLPYRSNVPY--L 499

Query: 546 AQVCMENYDAEF--RTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIF 603
           +  C+   D EF  + K + G I+V+G N+G GSSRE AA A +  GI  V++ SF  I 
Sbjct: 500 SNFCLTPCDEEFPEKAKENGGGIIVAGTNYGQGSSREHAALAPVYLGIKAVLAKSFARIH 559

Query: 604 SRNSINNALLTLEIPA--LIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDG 661
             N INN +L L          + E  +   + +  +     K D+ +    +   +L  
Sbjct: 560 KANLINNGILPLVFEREEDYDSIDEMDELVIENVLNQVE-IGKIDIINKTKGIKYKTLLE 618

Query: 662 PVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
               ++K          +I+KGGL   +KS
Sbjct: 619 ATDRQKK----------MILKGGLLNLIKS 638
Searching..................................................done Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

gb|EDN60567.1|  homoaconitase [Saccharomyces cerevisiae YJM789]   936   0.0  
ref|NP_010520.1|  Homoaconitase, catalyzes the conversion of...   935   0.0  
gb|AAU09698.1|  YDR234W [Saccharomyces cerevisiae]                933   0.0  
ref|XP_452878.1|  unnamed protein product [Kluyveromyces lac...   918   0.0  
ref|XP_664125.1|  LYS4_EMENI Homoaconitase, mitochondrial pr...   905   0.0  
sp|Q92412|LYS4_EMENI  Homoaconitase, mitochondrial precursor...   901   0.0  
ref|XP_001819597.1|  hypothetical protein [Aspergillus oryza...   900   0.0  
gb|EEH48819.1|  3-isopropylmalate dehydratase large subunit ...   896   0.0  
ref|XP_751171.1|  mitochondrial aconitate hydratase [Aspergi...   896   0.0  
gb|EDP55486.1|  mitochondrial aconitate hydratase, putative ...   894   0.0  
ref|XP_001396574.1|  hypothetical protein An15g00350 [Asperg...   892   0.0  
ref|XP_001248868.1|  hypothetical protein CIMG_02639 [Coccid...   892   0.0  
ref|XP_717326.1|  homoaconitase [Candida albicans SC5314] >g...   892   0.0  
ref|XP_001258433.1|  mitochondrial aconitate hydratase, puta...   892   0.0  
ref|XP_001268345.1|  mitochondrial aconitate hydratase, puta...   892   0.0  
ref|XP_001822935.1|  hypothetical protein [Aspergillus oryza...   892   0.0  
emb|CAD60751.1|  unnamed protein product [Podospora anserina...   891   0.0  
ref|XP_359935.2|  hypothetical protein MGG_04842 [Magnaporth...   889   0.0  
ref|XP_001911427.1|  unnamed protein product [Podospora anse...   889   0.0  
gb|AAC61778.1|  aconitase [Aspergillus terreus]                   889   0.0  
gb|ABH10644.1|  aconitase [Coccidioides posadasii]                888   0.0  
ref|XP_001247958.1|  aconitate hydratase, mitochondrial prec...   888   0.0  
ref|XP_001393157.1|  hypothetical protein An08g10530 [Asperg...   888   0.0  
ref|XP_460673.1|  hypothetical protein DEHA0F08019g [Debaryo...   887   0.0  
ref|XP_001834931.1|  hypothetical protein CC1G_10805 [Coprin...   887   0.0  
ref|XP_001383888.2|  homoaconitase [Pichia stipitis CBS 6054...   885   0.0  
ref|XP_445684.1|  unnamed protein product [Candida glabrata]...   884   0.0  
ref|XP_502616.1|  hypothetical protein [Yarrowia lipolytica]...   884   0.0  
ref|XP_001644039.1|  hypothetical protein Kpol_1026p29 [Vand...   883   0.0  
ref|XP_001878558.1|  aconitate hydratase [Laccaria bicolor S...   882   0.0  
sp|Q2HZ33|LYS4_CANPA  Homoaconitase, mitochondrial precursor...   882   0.0  
ref|XP_716225.1|  mitochondrial aconitate hydratase [Candida...   881   0.0  
ref|ZP_03966826.1|  aconitate hydratase [Sphingobacterium sp...   881   0.0  
ref|XP_001587807.1|  hypothetical protein SS1G_11047 [Sclero...   880   0.0  
ref|XP_001219634.1|  hypothetical protein CHGG_00413 [Chaeto...   879   0.0  
ref|XP_570245.1|  aconitase [Cryptococcus neoformans var. ne...   878   0.0  
ref|YP_678828.1|  aconitate hydratase [Cytophaga hutchinsoni...   878   0.0  
ref|XP_663129.1|  hypothetical protein AN5525.2 [Aspergillus...   877   0.0  
ref|XP_503471.1|  hypothetical protein [Yarrowia lipolytica]...   877   0.0  
gb|AAH26196.1|  Aconitase 2, mitochondrial [Homo sapiens]         876   0.0  
ref|ZP_00949139.1|  aconitate hydratase [Croceibacter atlant...   876   0.0  
ref|XP_001539249.1|  homoaconitase, mitochondrial precursor ...   876   0.0  
emb|CAG38805.1|  ACO2 [Homo sapiens]                              875   0.0  
ref|XP_448693.1|  unnamed protein product [Candida glabrata]...   875   0.0  
ref|XP_001485749.1|  hypothetical protein PGUG_01420 [Pichia...   875   0.0  
ref|NP_013407.1|  Aconitase, required for the tricarboxylic ...   874   0.0  
ref|YP_862527.1|  aconitate hydratase [Gramella forsetii KT0...   873   0.0  
ref|ZP_01061488.1|  aconitate hydratase [Flavobacterium sp. ...   873   0.0  
ref|XP_001646008.1|  hypothetical protein Kpol_1031p57 [Vand...   873   0.0  
gb|EEH41326.1|  homoaconitase [Paracoccidioides brasiliensis...   872   0.0  
gb|EEH50136.1|  homoaconitase [Paracoccidioides brasiliensis...   872   0.0  
gb|AAT92542.1|  mitochondrial aconitate hydratase [Yarrowia ...   872   0.0  
ref|XP_958836.1|  homoaconitase, mitochondrial precursor [Ne...   872   0.0  
ref|XP_360978.1|  conserved hypothetical protein [Magnaporth...   871   0.0  
ref|XP_001523113.1|  homoaconitase, mitochondrial precursor ...   870   0.0  
ref|XP_001486725.1|  conserved hypothetical protein [Pichia ...   870   0.0  
ref|XP_452974.1|  unnamed protein product [Kluyveromyces lac...   870   0.0  
ref|XP_959787.1|  hypothetical protein NCU02366 [Neurospora ...   869   0.0  
gb|ABZ96059.1|  Aconitate hydratase [Leptospira biflexa sero...   868   0.0  
ref|XP_001689702.1|  aconitate hydratase [Chlamydomonas rein...   868   0.0  
emb|CAA76360.1|  aconitate hydratase [Piromyces sp. E2]           866   0.0  
ref|XP_001879583.1|  aconitate hydratase 2 [Laccaria bicolor...   866   0.0  
ref|ZP_01107815.1|  aconitate hydratase [Flavobacteriales ba...   865   0.0  
ref|XP_388129.1|  hypothetical protein FG07953.1 [Gibberella...   865   0.0  
gb|EDU46563.1|  homoaconitase, mitochondrial precursor [Pyre...   865   0.0  
ref|ZP_03900244.1|  aconitase [Dyadobacter fermentans DSM 18...   865   0.0  
sp|P49609|ACON_GRAVE  Aconitate hydratase, mitochondrial pre...   865   0.0  
ref|XP_001525166.1|  aconitate hydratase, mitochondrial prec...   863   0.0  
ref|ZP_01733086.1|  aconitate hydratase [Flavobacteria bacte...   863   0.0  
ref|XP_641958.1|  aconitate hydratase [Dictyostelium discoid...   863   0.0  
ref|XP_001791786.1|  hypothetical protein SNOG_01131 [Phaeos...   863   0.0  
ref|NP_984065.1|  ADL032Wp [Ashbya gossypii ATCC 10895] >gi|...   862   0.0  
ref|ZP_03850820.1|  aconitate hydratase [Chryseobacterium gl...   862   0.0  
ref|ZP_01720574.1|  aconitate hydratase [Algoriphagus sp. PR...   862   0.0  
ref|ZP_01885744.1|  aconitate hydratase [Pedobacter sp. BAL3...   861   0.0  
ref|YP_003633.1|  aconitate hydratase [Leptospira interrogan...   861   0.0  
ref|NP_714871.1|  aconitate hydratase [Leptospira interrogan...   861   0.0  
ref|YP_001296062.1|  aconitate hydratase [Flavobacterium psy...   861   0.0  
ref|XP_001386080.1|  Aconitase, mitochondrial [Pichia stipit...   861   0.0  
gb|ABY84678.1|  homoaconitase [Penicillium chrysogenum]           861   0.0  
ref|YP_799496.1|  aconitate hydratase [Leptospira borgpeters...   860   0.0  
ref|XP_001607990.1|  PREDICTED: similar to aconitase, mitoch...   859   0.0  
ref|XP_759046.1|  hypothetical protein UM02899.1 [Ustilago m...   859   0.0  
ref|XP_459431.1|  hypothetical protein DEHA0E02948g [Debaryo...   858   0.0  
ref|YP_001039546.1|  aconitate hydratase [Clostridium thermo...   858   0.0  
ref|NP_594031.1|  aconitate hydratase [Schizosaccharomyces p...   858   0.0  
gb|AAA34389.1|  aconitase (ACO1) (EC 4.2.1.3)                     858   0.0  
ref|NP_214222.1|  aconitate hydratase [Aquifex aeolicus VF5]...   857   0.0  
ref|YP_001194303.1|  aconitate hydratase [Flavobacterium joh...   856   0.0  
ref|XP_001539799.1|  aconitate hydratase, mitochondrial prec...   856   0.0  
ref|XP_391994.1|  PREDICTED: similar to Aconitase CG9244-PB ...   855   0.0  
dbj|BAC65324.1|  hypothetical protein [Antheraea yamamai]         854   0.0  
ref|XP_391125.1|  hypothetical protein FG10949.1 [Gibberella...   854   0.0  
ref|ZP_01690421.1|  aconitate hydratase [Microscilla marina ...   853   0.0  
ref|XP_001598937.1|  hypothetical protein SS1G_01026 [Sclero...   853   0.0  
sp|P20004|ACON_BOVIN  Aconitate hydratase, mitochondrial pre...   852   0.0  
ref|XP_001502547.1|  PREDICTED: similar to Aconitate hydrata...   852   0.0  
ref|XP_001547913.1|  hypothetical protein BC1G_13341 [Botryo...   852   0.0  
gb|AAH68910.1|  LOC398139 protein [Xenopus laevis]                851   0.0  
ref|ZP_01252893.1|  aconitate hydratase [Psychroflexus torqu...   851   0.0  
ref|NP_001089.1|  aconitase 2 precursor [Homo sapiens] >gi|6...   851   0.0  
ref|XP_001728868.1|  hypothetical protein MGL_4035 [Malassez...   850   0.0  
dbj|BAE29252.1|  unnamed protein product [Mus musculus]           850   0.0  
gb|AAD19351.2|  aconitase [Homo sapiens]                          850   0.0  
ref|NP_077374.2|  aconitase 2, mitochondrial [Rattus norvegi...   850   0.0  
ref|XP_001502551.1|  PREDICTED: similar to Aconitate hydrata...   850   0.0  
gb|AAH94462.1|  Aconitase 2, mitochondrial [Mus musculus]         850   0.0  
emb|CAB72317.1|  aconitase [Daphnia pulex]                        850   0.0  
ref|NP_542364.1|  aconitase 2, mitochondrial [Mus musculus] ...   850   0.0  
ref|NP_524708.1|  Aconitase CG9244-PB, isoform B [Drosophila...   850   0.0  
ref|XP_001105023.1|  PREDICTED: similar to aconitase 2 precu...   850   0.0  
dbj|BAE25770.1|  unnamed protein product [Mus musculus]           850   0.0  
gb|AAB38416.1|  mitochondrial aconitase [Homo sapiens]            849   0.0  
emb|CAG30932.1|  hypothetical protein [Gallus gallus]             848   0.0  
ref|NP_989519.1|  aconitase 2, mitochondrial [Gallus gallus]...   848   0.0  
ref|XP_001664086.1|  aconitase, mitochondrial [Aedes aegypti...   848   0.0  
ref|ZP_01121752.1|  aconitate hydratase [Robiginitalea bifor...   848   0.0  
ref|NP_999119.1|  aconitase 2 [Sus scrofa] >gi|113159|sp|P16...   848   0.0  
gb|AAI02643.1|  Aconitase 2, mitochondrial [Bos taurus]           847   0.0  
ref|NP_622150.1|  aconitate hydratase [Thermoanaerobacter te...   847   0.0  
ref|XP_858344.1|  PREDICTED: similar to aconitase 2, mitocho...   847   0.0  
ref|XP_753748.1|  homoaconitase LysF [Aspergillus fumigatus ...   847   0.0  
pdb|5ACN|A  Chain A, Structure Of Activated Aconitase. Forma...   846   0.0  
ref|XP_001274165.1|  homoaconitase LysF [Aspergillus clavatu...   846   0.0  
ref|NP_927033.1|  aconitate hydratase [Gloeobacter violaceus...   846   0.0  
ref|XP_849166.1|  PREDICTED: similar to aconitase 2, mitocho...   846   0.0  
emb|CAC48042.1|  homoaconitase [Aspergillus fumigatus]            845   0.0  
ref|XP_001663037.1|  aconitase, mitochondrial [Aedes aegypti...   845   0.0  
gb|EDP51631.1|  homoaconitase LysF [Aspergillus fumigatus A1...   845   0.0  
ref|XP_974860.1|  PREDICTED: similar to CG9244-PB [Tribolium...   845   0.0  
ref|NP_776402.1|  aconitase 2, mitochondrial [Bos taurus] >g...   844   0.0  
gb|EEH33999.1|  3-isopropylmalate dehydratase large subunit ...   844   0.0  
ref|YP_001665791.1|  putative aconitate hydratase [Thermoana...   844   0.0  
ref|XP_712172.1|  mitochondrial aconitase [Candida albicans ...   844   0.0  
ref|ZP_02183105.1|  aconitate hydratase [Flavobacteriales ba...   844   0.0  
ref|YP_001179560.1|  aconitate hydratase [Caldicellulosirupt...   844   0.0  
pdb|1AMI|A  Chain A, Steric And Conformational Features Of T...   843   0.0  
pdb|1B0J|A  Chain A, Crystal Structure Of Aconitase With Iso...   843   0.0  
pdb|1ACO|A  Chain A, Crystal Structure Of Aconitase With Tra...   843   0.0  
pdb|1B0M|A  Chain A, Aconitase R644q:fluorocitrate Complex        843   0.0  
pdb|1C96|A  Chain A, S642a:citrate Complex Of Aconitase           843   0.0  
pdb|1C97|A  Chain A, S642a:isocitrate Complex Of Aconitase >...   843   0.0  
ref|XP_001357493.1|  GA21639-PA [Drosophila pseudoobscura] >...   843   0.0  
ref|XP_317642.4|  AGAP007852-PA [Anopheles gambiae str. PEST...   843   0.0  
ref|XP_001378711.1|  PREDICTED: similar to Aco2 protein [Mon...   842   0.0  
ref|XP_001259799.1|  homoaconitase LysF [Neosartorya fischer...   842   0.0  
pdb|1NIS|A  Chain A, Crystal Structure Of Aconitase With Tra...   842   0.0  
ref|NP_001011445.1|  aconitase 2, mitochondrial [Xenopus tro...   842   0.0  
ref|XP_452349.1|  unnamed protein product [Kluyveromyces lac...   841   0.0  
emb|CAC11018.1|  mitochondrial aconitase [Rattus norvegicus]      841   0.0  
ref|NP_944590.1|  aconitase 2, mitochondrial [Danio rerio] >...   841   0.0  
ref|ZP_02177697.1|  aconitate hydratase [Hydrogenivirga sp. ...   841   0.0  
ref|YP_213145.1|  aconitate hydratase [Bacteroides fragilis ...   841   0.0  
ref|YP_001299253.1|  aconitate hydratase [Bacteroides vulgat...   840   0.0  
ref|XP_001176556.1|  PREDICTED: similar to Aconitase 2, mito...   840   0.0  
ref|YP_162278.1|  aconitate hydratase [Zymomonas mobilis sub...   839   0.0  
ref|YP_101031.1|  aconitate hydratase [Bacteroides fragilis ...   839   0.0  
ref|YP_001394364.1|  Aconitase-related protein [Clostridium ...   839   0.0  
ref|XP_001525239.1|  aconitate hydratase, mitochondrial prec...   838   0.0  
ref|ZP_02081473.1|  hypothetical protein CLOLEP_02949 [Clost...   837   0.0  
gb|AAM10631.1|AF434843_1  aconitase protein [Bacteroides fra...   837   0.0  
ref|ZP_01202534.1|  aconitase A [Flavobacteria bacterium BBF...   837   0.0  
ref|ZP_01961523.1|  hypothetical protein BACCAC_03155 [Bacte...   837   0.0  
ref|XP_001666692.1|  hypothetical protein CBG22943 [Caenorha...   837   0.0  
ref|ZP_02615951.1|  aconitase/isopropylmalate dehydratase fa...   836   0.0  
ref|YP_001389789.1|  aconitase/isopropylmalate dehydratase f...   836   0.0  
emb|CAQ43555.1|  Probable aconitate hydratase 2 [Zygosacchar...   836   0.0  
emb|CAM25244.1|  aconitase 2, mitochondrial [Homo sapiens] >...   836   0.0  
ref|YP_001780072.1|  aconitase/isopropylmalate dehydratase f...   836   0.0  
ref|XP_001892954.1|  aconitate hydratase, mitochondrial [Bru...   835   0.0  
ref|YP_002802745.1|  aconitase/isopropylmalate dehydratase f...   835   0.0  
ref|XP_001104650.1|  PREDICTED: similar to aconitase 2 precu...   835   0.0  
ref|XP_001104944.1|  PREDICTED: similar to aconitase 2 precu...   835   0.0  
ref|NP_001086263.1|  MGC84375 protein [Xenopus laevis] >gi|4...   835   0.0  
ref|ZP_02423106.1|  hypothetical protein EUBSIR_01964 [Eubac...   834   0.0  
ref|NP_650042.2|  CG4706 CG4706-PA [Drosophila melanogaster]...   834   0.0  
ref|YP_001382802.1|  aconitase/isopropylmalate dehydratase f...   834   0.0  
ref|ZP_01576278.1|  putative aconitate hydratase [Clostridiu...   833   0.0  
ref|ZP_02060705.1|  putative aconitate hydratase [Hydrogenob...   833   0.0  
ref|XP_460250.1|  hypothetical protein DEHA0E23078g [Debaryo...   833   0.0  
ref|ZP_02066314.1|  hypothetical protein BACOVA_03310 [Bacte...   833   0.0  
ref|YP_001252962.1|  aconitate hydratase [Clostridium botuli...   832   0.0  
ref|NP_012335.1|  Putative mitochondrial aconitase isozyme; ...   832   0.0  
ref|ZP_02612428.1|  aconitase/isopropylmalate dehydratase fa...   832   0.0  
ref|ZP_01049156.1|  aconitate hydratase [Cellulophaga sp. ME...   832   0.0  
ref|ZP_02162366.1|  aconitate hydratase [Kordia algicida OT-...   831   0.0  
gb|ABE02803.1|  mitochondrial aconitase 2 [Bos taurus]            831   0.0  
ref|ZP_02070255.1|  hypothetical protein BACUNI_01674 [Bacte...   831   0.0  
ref|XP_001214855.1|  homoaconitase, mitochondrial precursor ...   831   0.0  
ref|YP_430725.1|  aconitate hydratase [Moorella thermoacetic...   830   0.0  
ref|XP_001359921.1|  GA18372-PA [Drosophila pseudoobscura] >...   830   0.0  
emb|CAJ73630.1|  similar to aconitase 1 (aconitate hydratase...   830   0.0  
ref|YP_001785758.1|  aconitase/isopropylmalate dehydratase f...   829   0.0  
ref|ZP_01051949.1|  aconitate hydratase [Tenacibaculum sp. M...   829   0.0  
ref|NP_347607.1|  aconitate hydratase [Clostridium acetobuty...   829   0.0  
ref|ZP_02436892.1|  hypothetical protein BACSTE_03162 [Bacte...   829   0.0  
ref|ZP_01118361.1|  aconitate hydratase [Polaribacter irgens...   828   0.0  
gb|EDN63190.1|  aconitase [Saccharomyces cerevisiae YJM789]       828   0.0  
ref|NP_810985.1|  aconitate hydratase [Bacteroides thetaiota...   828   0.0  
ref|XP_858265.1|  PREDICTED: similar to aconitase 2, mitocho...   828   0.0  
ref|XP_001385589.2|  aconitate hydratase [Pichia stipitis CB...   828   0.0  
ref|ZP_01891676.1|  aconitate hydratase [unidentified eubact...   828   0.0  
ref|YP_001678741.1|  aconitate hydratase, putative [Heliobac...   826   0.0  
gb|EAY57416.1|  Aconitase A [Leptospirillum sp. Group II UBA]     826   0.0  
ref|XP_001485951.1|  hypothetical protein PGUG_01622 [Pichia...   826   0.0  
ref|ZP_02032556.1|  hypothetical protein PARMER_02572 [Parab...   824   0.0  
ref|YP_001302462.1|  aconitate hydratase [Parabacteroides di...   824   0.0  
ref|NP_741235.1|  ACOnitase family member (aco-2) [Caenorhab...   821   0.0  
ref|XP_001747281.1|  predicted protein [Monosiga brevicollis...   821   0.0  
ref|YP_001307216.1|  aconitate hydratase [Clostridium beijer...   819   0.0  
ref|YP_001919567.1|  putative aconitate hydratase [Clostridi...   818   0.0  
ref|XP_001212503.1|  aconitate hydratase, mitochondrial prec...   817   0.0  
ref|XP_446075.1|  unnamed protein product [Candida glabrata]...   817   0.0  
ref|YP_001884383.1|  putative aconitate hydratase [Clostridi...   816   0.0  
ref|XP_001912055.1|  unnamed protein product [Podospora anse...   814   0.0  
dbj|BAD81058.1|  aconitase [Acidithiobacillus thiooxidans]        814   0.0  
ref|YP_001230042.1|  aconitate hydratase [Geobacter uraniire...   814   0.0  
ref|XP_001818998.1|  hypothetical protein [Aspergillus oryza...   814   0.0  
ref|YP_001087310.1|  aconitate hydratase [Clostridium diffic...   813   0.0  
ref|ZP_02726948.1|  aconitate hydratase [Clostridium diffici...   813   0.0  
ref|ZP_02742090.1|  aconitate hydratase [Clostridium diffici...   813   0.0  
ref|NP_596189.1|  aconitate hydratase [Schizosaccharomyces p...   812   0.0  
ref|XP_750430.1|  aconitate hydratase, mitochondrial [Asperg...   812   0.0  
ref|ZP_02951252.1|  putative aconitate hydratase [Clostridiu...   811   0.0  
gb|EEH99428.1|  aconitate hydratase [Clostridium sp. 7_2_43FAA]   811   0.0  
ref|XP_001224733.1|  hypothetical protein CHGG_07077 [Chaeto...   811   0.0  
ref|ZP_02993983.1|  hypothetical protein CLOSPO_01101 [Clost...   810   0.0  
ref|XP_001264984.1|  aconitate hydratase, mitochondrial [Neo...   809   0.0  
ref|ZP_01775867.1|  putative aconitate hydratase [Geobacter ...   809   0.0  
ref|XP_503960.1|  hypothetical protein [Yarrowia lipolytica]...   809   0.0  
ref|XP_961070.1|  hypothetical protein NCU04280 [Neurospora ...   808   0.0  
ref|XP_001646409.1|  hypothetical protein Kpol_2001p56 [Vand...   808   0.0  
ref|XP_001269477.1|  aconitate hydratase, mitochondrial [Asp...   808   0.0  
ref|ZP_01388850.1|  Putative aconitate hydratase [Geobacter ...   807   0.0  
ref|NP_969574.1|  aconitate hydratase [Bdellovibrio bacterio...   806   0.0  
ref|NP_953491.1|  aconitate hydratase [Geobacter sulfurreduc...   806   0.0  
gb|ACO69045.1|  isocitrate dehydrogenase/citrate hydrolyase ...   806   0.0  
ref|XP_001393703.1|  hypothetical protein An09g03870 [Asperg...   804   0.0  
ref|YP_344690.1|  aconitate hydratase [Nitrosococcus oceani ...   803   0.0  
ref|XP_001640014.1|  predicted protein [Nematostella vectens...   803   0.0  
ref|NP_986176.1|  AFR629Wp [Ashbya gossypii ATCC 10895] >gi|...   802   0.0  
gb|EEH43317.1|  aconitate hydratase [Paracoccidioides brasil...   801   0.0  
ref|XP_390374.1|  hypothetical protein FG10198.1 [Gibberella...   801   0.0  
gb|EEH37425.1|  aconitate hydratase [Paracoccidioides brasil...   801   0.0  
ref|XP_661498.1|  hypothetical protein AN3894.2 [Aspergillus...   801   0.0  
ref|YP_878649.1|  aconitate hydratase [Clostridium novyi NT]...   801   0.0  
gb|EEH52362.1|  isocitrate dehydrogenase/citrate hydrolyase ...   800   0.0  
ref|ZP_02868335.1|  hypothetical protein CLOSPI_02177 [Clost...   799   0.0  
ref|YP_842722.1|  aconitate hydratase [Methanosaeta thermoph...   799   0.0  
ref|ZP_02429558.1|  hypothetical protein CLORAM_02981 [Clost...   798   0.0  
ref|ZP_01291443.1|  Putative aconitate hydratase [delta prot...   798   0.0  
ref|YP_385706.1|  aconitate hydratase [Geobacter metalliredu...   797   0.0  
ref|XP_001104873.1|  PREDICTED: similar to aconitase 2 precu...   796   0.0  
ref|ZP_01287851.1|  Putative aconitate hydratase [delta prot...   795   0.0  
ref|NP_593437.1|  homoaconitate hydratase Lys2 [Schizosaccha...   795   0.0  
ref|NP_982841.1|  ABL106Cp [Ashbya gossypii ATCC 10895] >gi|...   794   0.0  
ref|YP_001582816.1|  aconitate hydratase [Nitrosopumilus mar...   794   0.0  
ref|XP_362853.1|  hypothetical protein MGG_08584 [Magnaporth...   794   0.0  
ref|ZP_02078010.1|  hypothetical protein EUBDOL_01817 [Eubac...   793   0.0  
ref|XP_001516809.1|  PREDICTED: hypothetical protein [Ornith...   793   0.0  
gb|EEK08352.1|  aconitase [Brachyspira murdochii DSM 12563]       793   0.0  
ref|YP_967373.1|  aconitate hydratase [Desulfovibrio vulgari...   792   0.0  
ref|YP_010285.1|  aconitate hydratase [Desulfovibrio vulgari...   791   0.0  
ref|XP_001244575.1|  hypothetical protein CIMG_04016 [Coccid...   789   0.0  
ref|YP_357859.1|  aconitate hydratase [Pelobacter carbinolic...   789   0.0  
ref|ZP_01594594.1|  putative aconitate hydratase [Geobacter ...   788   0.0  
ref|ZP_02621054.1|  putative aconitate hydratase [Clostridiu...   788   0.0  
ref|ZP_03929473.1|  possible aconitate hydratase [Anaerococc...   786   0.0  
ref|YP_001319181.1|  aconitate hydratase [Alkaliphilus metal...   786   0.0  
ref|XP_001909150.1|  unnamed protein product [Podospora anse...   786   0.0  
ref|XP_957462.1|  3-isopropylmalate dehydratase [Neurospora ...   786   0.0  
ref|NP_001097186.1|  Aconitase CG9244-PC, isoform C [Drosoph...   785   0.0  
ref|XP_001241042.1|  hypothetical protein CIMG_08205 [Coccid...   785   0.0  
ref|ZP_02133049.1|  putative aconitate hydratase [Desulfatib...   784   0.0  
ref|XP_001821962.1|  hypothetical protein [Aspergillus oryza...   784   0.0  
ref|YP_846224.1|  aconitate hydratase [Syntrophobacter fumar...   784   0.0  
sp|P55251|LEU2_RHIPU  3-isopropylmalate dehydratase (Isoprop...   782   0.0  
ref|XP_001746450.1|  predicted protein [Monosiga brevicollis...   782   0.0  
ref|YP_387900.1|  aconitate hydratase [Desulfovibrio desulfu...   782   0.0  
emb|CAD68161.1|  putative alpha-isopropylmalate isomerase [M...   781   0.0  
gb|EEJ79007.1|  aconitase [Anaerococcus prevotii DSM 20548]       780   0.0  
ref|XP_568476.1|  aconitate hydratase [Cryptococcus neoforma...   779   0.0  
emb|CAD68162.1|  putative alpha-isopropylmalate isomerase [M...   779   0.0  
ref|XP_001817167.1|  hypothetical protein [Aspergillus oryza...   778   0.0  
ref|ZP_02862126.1|  hypothetical protein ANASTE_01339 [Anaer...   778   0.0  
ref|NP_001081952.1|  aconitase [Xenopus laevis] >gi|6014626|...   776   0.0  
ref|ZP_03916351.1|  possible aconitate hydratase [Anaerococc...   774   0.0  
ref|XP_663490.1|  hypothetical protein AN5886.2 [Aspergillus...   774   0.0  
ref|XP_566619.1|  3-isopropylmalate dehydratase [Cryptococcu...   774   0.0  
ref|XP_001397884.1|  hypothetical protein An16g05760 [Asperg...   771   0.0  
ref|XP_001208815.1|  3-isopropylmalate dehydratase [Aspergil...   771   0.0  
ref|YP_461949.1|  aconitate hydratase [Syntrophus aciditroph...   770   0.0  
ref|YP_136708.1|  aconitate hydratase [Haloarcula marismortu...   769   0.0  
ref|XP_755459.1|  3-isopropylmalate dehydratase [Aspergillus...   769   0.0  
ref|ZP_02062283.1|  putative aconitate hydratase [Rickettsie...   769   0.0  
Sequences not found previously or not previously below threshold:

emb|CAG04508.1|  unnamed protein product [Tetraodon nigrovir...   866   0.0  
ref|XP_858303.1|  PREDICTED: similar to aconitase 2, mitocho...   835   0.0  
ref|XP_001802460.1|  hypothetical protein SNOG_12234 [Phaeos...   803   0.0  
ref|XP_662904.1|  hypothetical protein AN5300.2 [Aspergillus...   777   0.0  
ref|XP_001873889.1|  predicted protein [Laccaria bicolor S23...   771   0.0  
>gb|EDN60567.1| homoaconitase [Saccharomyces cerevisiae YJM789]
          Length = 693

 Score =  936 bits (2420), Expect = 0.0,   Method: Composition-based stats.
 Identities = 688/693 (99%), Positives = 688/693 (99%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLRSTT TRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRSTTLTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGATKIKNPSQIV TLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG
Sbjct: 61  WPVALKFMGLGATKIKNPSQIVNTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLNM VASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 121 IGHQIMIEEGYAFPLNMAVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW
Sbjct: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKI KADKDAHYAKKLI
Sbjct: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKILKADKDAHYAKKLI 300

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD
Sbjct: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP
Sbjct: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKI SPAEVLSTSEIPFSGVKTE
Sbjct: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKIGSPAEVLSTSEIPFSGVKTE 480

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
           IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV
Sbjct: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
           PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG
Sbjct: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD
Sbjct: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL
Sbjct: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
>ref|NP_010520.1| Homoaconitase, catalyzes the conversion of homocitrate to
           homoisocitrate, which is a step in the lysine
           biosynthesis pathway; Lys4p [Saccharomyces cerevisiae]
 sp|P49367|LYS4_YEAST Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAA63764.1| homoaconitase [Saccharomyces cerevisiae]
 gb|AAA88902.1| lysine biosynthesis enzyme homoaconitase [Saccharomyces cerevisiae]
          Length = 693

 Score =  935 bits (2418), Expect = 0.0,   Method: Composition-based stats.
 Identities = 693/693 (100%), Positives = 693/693 (100%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG
Sbjct: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW
Sbjct: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI
Sbjct: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD
Sbjct: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP
Sbjct: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE
Sbjct: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
           IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV
Sbjct: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
           PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG
Sbjct: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD
Sbjct: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL
Sbjct: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
>gb|AAU09698.1| YDR234W [Saccharomyces cerevisiae]
          Length = 693

 Score =  933 bits (2412), Expect = 0.0,   Method: Composition-based stats.
 Identities = 692/693 (99%), Positives = 693/693 (100%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG
Sbjct: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW
Sbjct: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI
Sbjct: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD
Sbjct: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP
Sbjct: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE
Sbjct: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
           IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV
Sbjct: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
           PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSRE+AATALLAKGINLVVSGSFG
Sbjct: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSRERAATALLAKGINLVVSGSFG 600

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD
Sbjct: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL
Sbjct: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
>ref|XP_452878.1| unnamed protein product [Kluyveromyces lactis]
 sp|Q6CT61|LYS4_KLULA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAH01729.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
          Length = 693

 Score =  918 bits (2373), Expect = 0.0,   Method: Composition-based stats.
 Identities = 549/695 (78%), Positives = 611/695 (87%), Gaps = 4/695 (0%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           M R     R F +SRA   GQN+TEKIVQ +AV LPEGK V SGDYVSIKPAHCMSHDNS
Sbjct: 1   MFRVQRL-RMFSTSRALYAGQNMTEKIVQRHAVGLPEGKTVVSGDYVSIKPAHCMSHDNS 59

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVALKFMGLGA+ IKNP Q+V TLDHD+QNKSEKNLTKYKNIENFAKKH ID YPAGRG
Sbjct: 60  WPVALKFMGLGASTIKNPRQVVNTLDHDVQNKSEKNLTKYKNIENFAKKHGIDFYPAGRG 119

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPL MTVASDSHSNTYGG+G+LGTPIVRTDAAAIWATGQTWWQIPPVA
Sbjct: 120 IGHQIMIEEGYAFPLTMTVASDSHSNTYGGIGALGTPIVRTDAAAIWATGQTWWQIPPVA 179

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKG+LP G+SGKDIIVALCG+FN DQVLNHAIEFTGDSL+ +PID+RLTIANMTTEW
Sbjct: 180 QVELKGELPAGISGKDIIVALCGVFNQDQVLNHAIEFTGDSLDKIPIDYRLTIANMTTEW 239

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVD  L+D+Y+NRL K   NNHPRIN   I  L+ K+   +AD DA YAKKLI
Sbjct: 240 GALSGLFPVDNVLLDFYRNRLTK-VGNNHPRINEARINELQAKSDSLQADPDAKYAKKLI 298

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDL+TLTHYVSGPNSVK+S+TV DLS+QDIK+NKAYLVSCTNSRLSDL+SAA+VVCP+GD
Sbjct: 299 IDLSTLTHYVSGPNSVKISSTVDDLSKQDIKVNKAYLVSCTNSRLSDLESAANVVCPSGD 358

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           +N+V+KVA GVEFY+AAASSE+EA+AR +GAW+KLL AGC+PLP+GCGPCIGLG GLLE 
Sbjct: 359 INQVHKVAEGVEFYIAAASSEVEAEARATGAWQKLLNAGCLPLPAGCGPCIGLGTGLLEE 418

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           G+VGISATNRNFKGRMGSKDALAYLASP+VVAASA+LGKI SPAEVL T +  F+GV   
Sbjct: 419 GQVGISATNRNFKGRMGSKDALAYLASPSVVAASAILGKIGSPAEVLGTKDPNFTGVVAT 478

Query: 481 IIENPVV--EEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQD 538
           + + P    + +  A       SVEILEGFP E SGELVLCDADNINTDGIYPGKYTYQD
Sbjct: 479 VEDAPATSADGKDVADESGASGSVEILEGFPSEISGELVLCDADNINTDGIYPGKYTYQD 538

Query: 539 DVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGS 598
           DVPKE MA+VCMENYD +F+TK +PGDI++SGFNFGTGSSREQAATA+LAKGI LVVSGS
Sbjct: 539 DVPKETMAKVCMENYDPDFQTKANPGDILISGFNFGTGSSREQAATAILAKGIKLVVSGS 598

Query: 599 FGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGS 658
           FGNIF RNSINNALLTLEIPALI  LR++Y+ APKELTRRTGWFLKWDV+ AKV VTEGS
Sbjct: 599 FGNIFFRNSINNALLTLEIPALINMLRDRYKDAPKELTRRTGWFLKWDVSQAKVYVTEGS 658

Query: 659 LDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           ++GP++LEQKVGELGKNLQEIIVKGGLE WVKSQL
Sbjct: 659 VNGPIVLEQKVGELGKNLQEIIVKGGLESWVKSQL 693
>ref|XP_664125.1| LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate
           hydratase) [Aspergillus nidulans FGSC A4]
 gb|EAA57861.1| LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate
           hydratase) [Aspergillus nidulans FGSC A4]
          Length = 776

 Score =  905 bits (2341), Expect = 0.0,   Method: Composition-based stats.
 Identities = 416/729 (57%), Positives = 505/729 (69%), Gaps = 42/729 (5%)

Query: 3   RSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWP 62
            S     + +SS+A    Q LTEKIVQ Y+V LP+GK V SGDYV+I+P  CM+HDNSWP
Sbjct: 50  TSAALFSALNSSKAV--PQTLTEKIVQKYSVGLPQGKFVKSGDYVTIQPHRCMTHDNSWP 107

Query: 63  VALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIG 122
            ALKFM +GA+++ NP QIV TLDHD+QNKS+KNL KY+ IE FA +H ++ YPAGRGIG
Sbjct: 108 CALKFMSIGASRLHNPDQIVMTLDHDVQNKSDKNLKKYRQIEEFATQHGVEFYPAGRGIG 167

Query: 123 HQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQV 182
           HQIMIEEG+A+P  + VASDSHSN YGG+G LGTPIVRTDAA++WATG+TWWQIPPVA+V
Sbjct: 168 HQIMIEEGFAWPGTLAVASDSHSNMYGGVGCLGTPIVRTDAASVWATGKTWWQIPPVAKV 227

Query: 183 ELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEW 240
             KG LP GV+GKD+IVALCGLFN D VLNHAIEFTG  +++ +L +D RLTIANMTTEW
Sbjct: 228 TFKGVLPPGVTGKDVIVALCGLFNKDDVLNHAIEFTGSEETMRSLSVDTRLTIANMTTEW 287

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRAL-------EEKAKIPKADKDA 293
           GALSGLFP+D  L  W + +                           +       ADK A
Sbjct: 288 GALSGLFPIDSVLKGWLRGKATTAAMGLADGPFKTRAAERFTHPLLEQLFENPLTADKGA 347

Query: 294 HYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAAD 353
            YAK+L +DL++L+ YVSGPNSVKV+  +++L  Q+IK++KAYLVSCTNSR SD+ +AA 
Sbjct: 348 KYAKELFLDLSSLSPYVSGPNSVKVATPLKELEAQNIKVDKAYLVSCTNSRASDIAAAAK 407

Query: 354 VVCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCI 411
           V     + N     K+A GV+FY+AAAS   +  A  +G W+ LL+AG   LP+GCGPCI
Sbjct: 408 VFKEAAEKNGGKIPKIADGVKFYIAAASIPEQLAAEGNGDWQTLLEAGATQLPAGCGPCI 467

Query: 412 GLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSE 471
           G+G GLLEPGEVGISA+NRNFKGRMGS +A AYL SP VVAASA+ GK+S P    +   
Sbjct: 468 GMGQGLLEPGEVGISASNRNFKGRMGSTEAKAYLGSPEVVAASALSGKLSGPGWYQTPEG 527

Query: 472 I------PFSGVKTE---------------IIENPVVE------EEVNAQTEAPKQSVEI 504
                     G++ E                +++ V +       E  A  E+ +   EI
Sbjct: 528 WTEVIRGEGDGIREEDRMLTNEEALEKIIGQLDDLVADGEKRFASETPAVEESEQGLTEI 587

Query: 505 LEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPG 564
             GFP   SGELV CDADN+NTDGIYPGKYTYQDDVP E MA+VCMENYD EF T    G
Sbjct: 588 YPGFPERVSGELVFCDADNVNTDGIYPGKYTYQDDVPPETMARVCMENYDPEFSTTAKEG 647

Query: 565 DIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKL 624
           DI+VSGFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P L+ +L
Sbjct: 648 DILVSGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLVNRL 707

Query: 625 REKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGG 684
           RE +    K LTRRTGW L WDV  +++ V EG   G      KVGEL  N+QEII KGG
Sbjct: 708 RETFGSGDKVLTRRTGWTLTWDVRKSQIEVQEGP--GGPKWTHKVGELPPNVQEIIAKGG 765

Query: 685 LEGWVKSQL 693
           LE WVK+ +
Sbjct: 766 LEKWVKNAI 774
>sp|Q92412|LYS4_EMENI Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAA67943.1| homoaconitase [Emericella nidulans]
          Length = 775

 Score =  901 bits (2329), Expect = 0.0,   Method: Composition-based stats.
 Identities = 415/729 (56%), Positives = 504/729 (69%), Gaps = 43/729 (5%)

Query: 3   RSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWP 62
            S     + +SS+A    Q LTEKIVQ Y+V LP+GK V SGDYV+I+P  CM+HDNSWP
Sbjct: 50  TSAALFSALNSSKAV--PQTLTEKIVQKYSVGLPQGKFVKSGDYVTIQPHRCMTHDNSWP 107

Query: 63  VALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIG 122
            ALKFM +GA+++ NP QIV TLDHD+QNKS+KNL KY+ IE FA +H ++ YPAGRGIG
Sbjct: 108 CALKFMSIGASRLHNPDQIVMTLDHDVQNKSDKNLKKYRQIEEFATQHGVEFYPAGRGIG 167

Query: 123 HQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQV 182
           HQIMIEEG+A+P  + VASDSHSN YGG+G LGTPIVRTDAA++WATG+TWWQIPPVA+V
Sbjct: 168 HQIMIEEGFAWPGTLAVASDSHSNMYGGVGCLGTPIVRTDAASVWATGKTWWQIPPVAKV 227

Query: 183 ELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEW 240
             KG LP GV+GKD+IVALCGLFN D VLNHAIEFTG  +++ +L +D RLTIANMTTEW
Sbjct: 228 TFKGVLPPGVTGKDVIVALCGLFNKDDVLNHAIEFTGSEETMRSLSVDTRLTIANMTTEW 287

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRAL-------EEKAKIPKADKDA 293
           GALSGLFP+D  L  W + +                           +       ADK A
Sbjct: 288 GALSGLFPIDSVLKGWLRGKATTAAMGLADGPFKTRAAERFTHPLLEQLFENPLTADKGA 347

Query: 294 HYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAAD 353
            YAK+L +DL++L+ YVSGPNSVKV+  +++L  Q+IK++KAYLVSCTNSR SD+ +AA 
Sbjct: 348 KYAKELFLDLSSLSPYVSGPNSVKVATPLKELEAQNIKVDKAYLVSCTNSRASDIAAAAK 407

Query: 354 VVCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCI 411
           V     + N     K+  GV+FY+AAAS   +  A  +G W+ LL+AG   LP+GCGPCI
Sbjct: 408 VFKEAAEKNGGKIPKIH-GVKFYIAAASIPEQLAAEGNGDWQTLLEAGATQLPAGCGPCI 466

Query: 412 GLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSE 471
           G+G GLLEPGEVGISA+NRNFKGRMGS +A AYL SP VVAASA+ GK+S P    +   
Sbjct: 467 GMGQGLLEPGEVGISASNRNFKGRMGSTEAKAYLGSPEVVAASALSGKLSGPGWYQTPEG 526

Query: 472 I------PFSGVKTE---------------IIENPVVE------EEVNAQTEAPKQSVEI 504
                     G++ E                +++ V +       E  A  E+ +   EI
Sbjct: 527 WTEVIRGEGDGIREEDRMLTNEEALEKIIGQLDDLVADGEKRFASETPAVEESEQGLTEI 586

Query: 505 LEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPG 564
             GFP   SGELV CDADN+NTDGIYPGKYTYQDDVP E MA+VCMENYD EF T    G
Sbjct: 587 YPGFPERVSGELVFCDADNVNTDGIYPGKYTYQDDVPPETMARVCMENYDPEFSTTAKEG 646

Query: 565 DIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKL 624
           DI+VSGFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P L+ +L
Sbjct: 647 DILVSGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLVNRL 706

Query: 625 REKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGG 684
           RE +    K LTRRTGW L WDV  +++ V EG   G      KVGEL  N+QEII KGG
Sbjct: 707 RETFGSGDKVLTRRTGWTLTWDVRKSQIEVQEGP--GGPKWTHKVGELPPNVQEIIAKGG 764

Query: 685 LEGWVKSQL 693
           LE WVK+ +
Sbjct: 765 LEKWVKNAI 773
>ref|XP_001819597.1| hypothetical protein [Aspergillus oryzae RIB40]
 dbj|BAE57595.1| unnamed protein product [Aspergillus oryzae]
          Length = 779

 Score =  900 bits (2326), Expect = 0.0,   Method: Composition-based stats.
 Identities = 166/762 (21%), Positives = 285/762 (37%), Gaps = 98/762 (12%)

Query: 2   LRSTTFTRSFHSSRAWL-KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +     + +    R  L +     EKI+ S+  N  E  +     Y+ ++P      D +
Sbjct: 42  INYKKMSENLEIVRKRLSRPLTYAEKILYSHLDNPHEQDIERGVSYLKLRPDRVACQDAT 101

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G   +  P+ +    DH I+            +E N   Y  + +   K
Sbjct: 102 AQMAILQFMSAGMPSVATPTTV--HCDHLIEAQVGGEKDLARANEINKEVYDFLASATAK 159

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  YAFP  + + +DSH+   GGLG     +   DA  + A 
Sbjct: 160 YNIGFWKPGSGIIHQIVLEN-YAFPGGLMIGTDSHTPNGGGLGMAAIGVGGADAVDVMAG 218

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V+L G+L    + KDII+ + GL          +E+ G  +N+L    
Sbjct: 219 LPWELKAPKVIGVKLTGELSGWTTPKDIILKVAGLLTVKGGTGAIVEYHGPGVNSLSCTG 278

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + LFP +  + D+ K   ++                     K  + 
Sbjct: 279 MGTICNMGAEIGATTSLFPYNDRMYDYLKATKRQHIG-----------DFARSYQKELRE 327

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +    +         ++    + SCTNS
Sbjct: 328 DEGAEYDQLIEINLSELEPHINGPFTPDLATPISKFKEAVEANKWPEELKVGLIGSCTNS 387

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     D      +     F +   S +I A   + G  + L + G + L
Sbjct: 388 SYEDMSRAASIARDALDHG----LKSKSLFTITPGSEQIRATIERDGQLQTLEEYGGVIL 443

Query: 404 PSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    IS+ NRNF GR   +    +++ SP +V A  V G 
Sbjct: 444 ANACGPCIGQWDRKDVKKGEANSIISSYNRNFTGRNDANPATHSFVTSPDLVVAMTVAGT 503

Query: 460 I-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           +               E      +   +P   +   +      PV    VN         
Sbjct: 504 LKFNPLTDTLKDKDGKEFKLKPPTGEGLPAKGYDPGRNTYQAPPVDRSTVNVAVSPTSDR 563

Query: 502 VEILEGFPREFSG-----ELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           +++L+GF            +++        D+I+  G +     + D++    +   V  
Sbjct: 564 LQVLQGFQAWDGKDATNIPILIKCQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAVNA 623

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN +A        G                   +V+  +N+G GSSRE AA      G  
Sbjct: 624 ENGEANKVKNAFTGEYDAVPATARDYKARGVKWVVIGDWNYGEGSSREHAALEPRHLGGL 683

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    PA   K++   +          G  +   V   
Sbjct: 684 AIITRSFARIHETNLKKQGMLPLTFAEPADYDKIQPDDKVDLLCTELEVGKPMTLRV--- 740

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
                    DG     +      ++  E    G     +  +
Sbjct: 741 ------HPKDGKTFDIKLNHTFNESQIEWFKDGSALNTMARK 776
>gb|EEH48819.1| 3-isopropylmalate dehydratase large subunit [Paracoccidioides
           brasiliensis Pb18]
          Length = 754

 Score =  896 bits (2317), Expect = 0.0,   Method: Composition-based stats.
 Identities = 161/762 (21%), Positives = 279/762 (36%), Gaps = 98/762 (12%)

Query: 2   LRSTTFTRSFHSSR-AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +       +    R    +     EKI+ S+  +  E  +     Y+ ++P      D +
Sbjct: 17  INYKKMAENLDIVRSRLNRPLTYAEKIMYSHLDDPHEQDIHRGKSYLKLRPDRVACQDAT 76

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G   +  P+ +    DH I+            +E N   Y  +     K
Sbjct: 77  AQMAILQFMSAGMPSVATPASV--HCDHLIEAQVGGEKDLARANEINKEVYDFLSTSCAK 134

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  YAFP  + + +DSH+   GGLG     +   DA  + A 
Sbjct: 135 YNIGFWKPGSGIIHQILLEN-YAFPGGLMIGTDSHTPNGGGLGMAAIGVGGADAVDVMAG 193

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V L G+L    S KDII+ + G+          IE+ G  +N+L    
Sbjct: 194 LPWELKAPKVIGVRLTGKLSGWTSPKDIILKVAGILTVKGGTGAIIEYHGPGVNSLSCTG 253

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + +FP +  + D+ K   ++                    A   + 
Sbjct: 254 MGTICNMGAEIGATTSVFPFNDRMYDYLKATKRQAIG-----------DFARSYAHSLRE 302

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +              ++    + SCTNS
Sbjct: 303 DEGAEYDQLIEINLSELEPHINGPFTPDLATPISKFKDAVKENGWPEELKVGLIGSCTNS 362

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     D      +     F V   S +I A   + G  + L + G + L
Sbjct: 363 SYEDMSRAASIARDALDHG----IKAKSLFTVTPGSEQIRATIERDGQLKTLEEFGGVIL 418

Query: 404 PSGCGPCIGLG-AGLLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    +S+ NRNF GR   +    A++ SP +V A  + G 
Sbjct: 419 ANACGPCIGQWDRRDVKKGEANSIVSSYNRNFTGRNDANPATHAFVTSPDLVVAMTIAGT 478

Query: 460 IS-----------SPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           ++              E      + + +P   +   +      P     ++         
Sbjct: 479 LNFNPLTDTLKDKDGKEFKLKEPTGAGLPANGYDPGRDTYQAPPKDRSSISVAVSPTSDR 538

Query: 502 VEILEGFPRE-----FSGELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           ++IL+ F            +++        D+I+  G +     + D++    +   +  
Sbjct: 539 LQILKAFQPWDGKDALGIPILIKAQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAINA 598

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN +A        G                   +V+  +N+G GSSRE AA      G  
Sbjct: 599 ENGEANKVKNFKTGEYGPVPATARDYKARGIKWVVIGDWNYGEGSSREHAALEPRHLGGL 658

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    PA   ++R              G  +   V   
Sbjct: 659 AIITRSFARIHETNLKKQGMLPLTFTDPADYDRIRPDDTVDLMCTELAVGKPITLRV--- 715

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
                  S D  +       +L     +    G     +  Q
Sbjct: 716 -HPKNGKSFDISLSHTFNEPQL-----QWFKDGSALNTMAKQ 751
>ref|XP_751171.1| mitochondrial aconitate hydratase [Aspergillus fumigatus Af293]
 gb|EAL89133.1| mitochondrial aconitate hydratase, putative [Aspergillus fumigatus
           Af293]
          Length = 787

 Score =  896 bits (2316), Expect = 0.0,   Method: Composition-based stats.
 Identities = 162/762 (21%), Positives = 285/762 (37%), Gaps = 97/762 (12%)

Query: 2   LRSTTFTRSFHSSRAWL-KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +     + +    R  L +     EK++ S+  +    ++     Y+ ++P      D +
Sbjct: 48  INYKKMSENLDIVRRRLQRPLTYAEKVLYSHLDDPHGQEIERGKSYLKLRPDRVACQDAT 107

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G   +  P+ +    DH I+            +E N   Y  + +   K
Sbjct: 108 AQMAILQFMSAGMPSVATPTTV--HCDHLIEAQVGGDKDLARANEINKEVYDFLASATAK 165

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  YAFP  + + +DSH+   GGL      +   DA  + A 
Sbjct: 166 YNIGFWKPGSGIIHQIVLEN-YAFPGGLMIGTDSHTPNAGGLAMAAIGVGGADAVDVMAG 224

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V+L G++    + KD+I+ + GL          IE+ G  + +L    
Sbjct: 225 LPWELKAPKVIGVKLTGEMSGWTTPKDVILKVAGLLTVKGGTGAIIEYHGPGVTSLSCTG 284

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + +FP +  + D+ K   ++                  E AK  + 
Sbjct: 285 MGTICNMGAEIGATTSMFPFNDRMYDYLKATKRQHIG-----------DFAREYAKELRE 333

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +    +         ++    + SCTNS
Sbjct: 334 DEGAEYDQLIEINLSELEPHINGPFTPDLATPISKFKEAVETNKWPEELKVGLIGSCTNS 393

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     +      +     F V   S +I A   + G  + L + G + L
Sbjct: 394 SYEDMSRAASIARDALNHG----LKAKSLFTVTPGSEQIRATIERDGQLQTLEEFGGVIL 449

Query: 404 PSGCGPCIGLG-AGLLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    IS+ NRNF GR   +    A++ASP +V A  + G 
Sbjct: 450 ANACGPCIGQWDRRDVKKGEPNSIISSYNRNFTGRNDANPATHAFVASPDLVVAMTIAGT 509

Query: 460 I-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           +               E      +   +P   +   +      P     VN         
Sbjct: 510 LKFNPLTDKLKDKDGNEFLLQPPTGEGLPAKGYDPGRDTYQAPPADRSSVNVAVSPTSDR 569

Query: 502 VEILEGFPREFSG-----ELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           +++L GF            +++        D+I+  G +     + D++    +   V  
Sbjct: 570 LQLLAGFEPWDGKDANGIPILIKCQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAVNA 629

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN  A        G                   +V+  +N+G GSSRE AA      G  
Sbjct: 630 ENGKANSVKNKFTGEYDAVPATARDYKARGVKWVVIGDWNYGEGSSREHAALEPRHLGGL 689

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    PA   K+  +            G  +       
Sbjct: 690 AIITRSFARIHETNLKKQGMLPLTFADPADYDKINPEDTVDLLCTQLEVGKPMTL----- 744

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
           +V   +GS    + L        ++  E    G     +  +
Sbjct: 745 RVHPKDGSAPFDISLNHT---FNESQIEWFKDGSALNTMARK 783
>gb|EDP55486.1| mitochondrial aconitate hydratase, putative [Aspergillus fumigatus
           A1163]
          Length = 779

 Score =  894 bits (2312), Expect = 0.0,   Method: Composition-based stats.
 Identities = 163/763 (21%), Positives = 286/763 (37%), Gaps = 97/763 (12%)

Query: 1   MLRSTTFTRSFHSSRAWL-KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDN 59
           M  +   + +    R  L +     EK++ S+  +    ++     Y+ ++P      D 
Sbjct: 39  MANTEKMSENLDIVRRRLQRPLTYAEKVLYSHLDDPHGQEIERGKSYLKLRPDRVACQDA 98

Query: 60  SWPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAK 108
           +  +A L+FM  G   +  P+ +    DH I+            +E N   Y  + +   
Sbjct: 99  TAQMAILQFMSAGMPSVATPTTV--HCDHLIEAQVGGDKDLARANEINKEVYDFLASATA 156

Query: 109 KHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWA 168
           K++I  +  G GI HQI++E  YAFP  + + +DSH+   GGL      +   DA  + A
Sbjct: 157 KYNIGFWKPGSGIIHQIVLEN-YAFPGGLMIGTDSHTPNAGGLAMAAIGVGGADAVDVMA 215

Query: 169 TGQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPID 228
                 + P V  V+L G++    + KD+I+ + GL          IE+ G  + +L   
Sbjct: 216 GLPWELKAPKVIGVKLTGEMSGWTTPKDVILKVAGLLTVKGGTGAIIEYHGPGVTSLSCT 275

Query: 229 HRLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPK 288
              TI NM  E GA + +FP +  + D+ K   ++                  E AK  +
Sbjct: 276 GMGTICNMGAEIGATTSMFPFNDRMYDYLKATKRQHIG-----------DFAREYAKELR 324

Query: 289 ADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTN 342
            D+ A Y + + I+L+ L  +++GP +  ++  +    +         ++    + SCTN
Sbjct: 325 EDEGAEYDQLIEINLSELEPHINGPFTPDLATPISKFKEAVETNKWPEELKVGLIGSCTN 384

Query: 343 SRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIP 402
           S   D+  AA +     +      +     F V   S +I A   + G  + L + G + 
Sbjct: 385 SSYEDMSRAASIARDALNHG----LKAKSLFTVTPGSEQIRATIERDGQLQTLEEFGGVI 440

Query: 403 LPSGCGPCIGLG-AGLLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLG 458
           L + CGPCIG      ++ GE    IS+ NRNF GR   +    A++ASP +V A  + G
Sbjct: 441 LANACGPCIGQWDRRDVKKGEPNSIISSYNRNFTGRNDANPATHAFVASPDLVVAMTIAG 500

Query: 459 KI-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQ 500
            +               E      +   +P   +   +      P     VN        
Sbjct: 501 TLKFNPLTDKLKDKDGNEFLLQPPTGEGLPAKGYDPGRDTYQAPPADRSSVNVAVSPTSD 560

Query: 501 SVEILEGFPREFSG-----ELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVC 549
            +++L GF            +++        D+I+  G +     + D++    +   V 
Sbjct: 561 RLQLLAGFEPWDGKDANGIPILIKCQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAVN 620

Query: 550 MENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGI 591
            EN  A        G                   +V+  +N+G GSSRE AA      G 
Sbjct: 621 AENGKANSVKNKFTGEYDAVPATARDYKARGVKWVVIGDWNYGEGSSREHAALEPRHLGG 680

Query: 592 NLVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVAD 649
             +++ SF  I   N     +L L    PA   K+  +            G  +      
Sbjct: 681 LAIITRSFARIHETNLKKQGMLPLTFADPADYDKINPEDTVDLLCTQLEVGKPMTL---- 736

Query: 650 AKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
            +V   +GS    + L        ++  E    G     +  +
Sbjct: 737 -RVHPKDGSAPFDISLNHT---FNESQIEWFKDGSALNTMARK 775
>ref|XP_001396574.1| hypothetical protein An15g00350 [Aspergillus niger]
 sp|Q58FL6|LYS4_ASPNC Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|AAX53108.1| homoaconitate hydratase [Aspergillus niger]
 emb|CAK42204.1| unnamed protein product [Aspergillus niger]
          Length = 769

 Score =  892 bits (2307), Expect = 0.0,   Method: Composition-based stats.
 Identities = 406/726 (55%), Positives = 498/726 (68%), Gaps = 42/726 (5%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S     S  SSRA    Q LTEKIVQ YAV LP+GK V SGDYV+I P   M+HDNSWPV
Sbjct: 48  SAALFSSLQSSRAV--PQTLTEKIVQKYAVGLPDGKFVKSGDYVTIAPHRIMTHDNSWPV 105

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GA+K+ +P+Q+V TLDHD+QNK+EKNL KY+ IE FAK+H ++ YPAGRGIGH
Sbjct: 106 ALKFMSIGASKMHDPNQVVMTLDHDVQNKTEKNLQKYRQIEEFAKQHGVEFYPAGRGIGH 165

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEG+A+P  + VASDSHSNTYG + S+GTPIVRTDAA+IWATG+TWWQIPPVA+V 
Sbjct: 166 QIMVEEGFAWPGTLVVASDSHSNTYGAVASVGTPIVRTDAASIWATGKTWWQIPPVAKVT 225

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
             G LP GV+GKD+IVALCGLF+ D VLNHAIEFTG  +++ +LP+D RLTIANMTTEWG
Sbjct: 226 FTGILPPGVTGKDVIVALCGLFDKDDVLNHAIEFTGSEETMRSLPMDSRLTIANMTTEWG 285

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNH-------PRINPKTIRALEEKAKIPKADKDAH 294
           ALSGLFP+D  L  W K +                   N       +       ADK A 
Sbjct: 286 ALSGLFPMDGVLKGWLKGKATTAAMGLADGPFKTLAARNFTHPAIEQLFVNPLTADKGAK 345

Query: 295 YAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADV 354
           YAK+L +DL+TL+ YVSGPNSVK++  +++L  QDIK++KAYLVSCTNSR SD+ +AA V
Sbjct: 346 YAKELFLDLSTLSPYVSGPNSVKIATPLKELEAQDIKVDKAYLVSCTNSRASDIAAAAKV 405

Query: 355 VCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIG 412
                + N     K+A GV+FY+AAAS   +  A  +G W+ LL+AG   LP+GCGPCIG
Sbjct: 406 FKDAAEKNGGKVPKIADGVKFYIAAASIPEQLAAEGAGDWQTLLEAGATALPAGCGPCIG 465

Query: 413 LGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEI 472
           LG GLLEPGEVGISA+NRNFKGRMGS +A AYL SP +VAASA+ GK+S P         
Sbjct: 466 LGTGLLEPGEVGISASNRNFKGRMGSTEAKAYLGSPEIVAASALSGKLSGPGWYQPPEGW 525

Query: 473 ------PFSGVK-------------------TEIIENPVVEEEVNAQTEAPKQSVEILEG 507
                    G++                    +++ +         + E      E+  G
Sbjct: 526 TEVVRGEGDGIREEDRMLNTEQALEKLLGQLDDLVADGEKRFAPEEKVEEEGGLTEVYPG 585

Query: 508 FPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIV 567
           FP   SGE+V CDADN+NTD IYPG +TYQD+VP EKMA+VCM NYD EF +    GDI+
Sbjct: 586 FPERVSGEIVFCDADNLNTDAIYPGYWTYQDNVPVEKMAEVCMSNYDKEFASIAKEGDIL 645

Query: 568 VSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREK 627
           V G+NFG GSSREQAATALLAK I LVVSGSFGNIFSRNSINNAL+ LE+P L+ +LRE+
Sbjct: 646 VVGYNFGCGSSREQAATALLAKQIPLVVSGSFGNIFSRNSINNALMGLEVPRLVSRLREE 705

Query: 628 YQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEG 687
           +    K+LTRRTGW L WDV  +++ + EG          KVGEL  N+QEII KGGLE 
Sbjct: 706 F--GDKQLTRRTGWTLTWDVRRSQIEIQEGQN--GPKWTHKVGELPPNVQEIIAKGGLEK 761

Query: 688 WVKSQL 693
           WVK+ +
Sbjct: 762 WVKNAI 767
>ref|XP_001248868.1| hypothetical protein CIMG_02639 [Coccidioides immitis RS]
 gb|EAS37285.1| hypothetical protein CIMG_02639 [Coccidioides immitis RS]
          Length = 801

 Score =  892 bits (2305), Expect = 0.0,   Method: Composition-based stats.
 Identities = 411/727 (56%), Positives = 504/727 (69%), Gaps = 41/727 (5%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           +     +  SS+A    Q LTEKIVQ Y+V LP+ K V SGDYV+I P   M+HDNSWPV
Sbjct: 77  AAAILSAMESSKAV--PQTLTEKIVQRYSVGLPKDKYVKSGDYVTISPHRVMTHDNSWPV 134

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GA+K+ +P+QIV TLDHD+QNKSEKNL KY+ IE FAK H +D YPAGRGIGH
Sbjct: 135 ALKFMSIGASKLNDPNQIVMTLDHDVQNKSEKNLKKYEQIETFAKTHGVDFYPAGRGIGH 194

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEGYA+P  + VASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V 
Sbjct: 195 QIMVEEGYAWPGTLVVASDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVT 254

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWG 241
            +G LP+GV+GKD+IVALCGLF+ D VLNHAIEFTG  +++ ++ ID RLTIANMTTEWG
Sbjct: 255 FRGVLPKGVTGKDVIVALCGLFDKDDVLNHAIEFTGSEETMRSIHIDDRLTIANMTTEWG 314

Query: 242 ALSGLFPVDKTLIDWYKNRLQK--------LGTNNHPRINPKTIRALEEKAKIPKADKDA 293
           ALSGLFPVD  L  W +++               +      K     +   +   ADK A
Sbjct: 315 ALSGLFPVDSMLKGWLRSKATTAAMWGSTVPELQSSAAERFKHAALDQLFEEPLVADKGA 374

Query: 294 HYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAAD 353
            YAK+L +DL+TL+ YV+GPNSVKV+  +++L  Q+IK+NKAYLVSCTNSR SD+ +AA 
Sbjct: 375 KYAKELFLDLSTLSPYVAGPNSVKVATPLKELESQNIKVNKAYLVSCTNSRASDIAAAAK 434

Query: 354 VVCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCI 411
           V     + N     K+A GV+FY+AAAS   +  A ++G W+ LL+AG  PLP+GCGPCI
Sbjct: 435 VFKEAAEKNGGKIPKIADGVKFYIAAASIPEQRAAEEAGDWQALLEAGAEPLPAGCGPCI 494

Query: 412 GLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSE 471
           GLG GLLEPGEVGISATNRNFKGRMGS +A AYL+SP VVAASA+ G IS P        
Sbjct: 495 GLGTGLLEPGEVGISATNRNFKGRMGSTEAKAYLSSPEVVAASALSGTISGPGWYEKPEG 554

Query: 472 IP----FSGVKTEIIENPVVEEEVNAQTE---APKQSV---------------EILEGFP 509
                   G   E+I      E+V  Q +      + +               E+  GFP
Sbjct: 555 WTGVVRGEGDGNEMITAEQALEKVIGQLDSMVEDAEKLFASEESNSSGEEGLTEVYPGFP 614

Query: 510 REFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVS 569
              SGE+V CDADNINTDGIYPGKYTYQD++P E+M + CMENYD +F      GDI+V+
Sbjct: 615 ERVSGEIVFCDADNINTDGIYPGKYTYQDNIPYEQMGEYCMENYDTQFGKVAKAGDILVT 674

Query: 570 GFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLRE--- 626
           G+NFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P LI +LRE   
Sbjct: 675 GYNFGCGSSREQAATAILAKQIPLVVSGSFGNIFSRNSINNALMGLEVPRLITRLRETFG 734

Query: 627 KYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLE 686
             +   K+LTRRTGW L WDV  +++ + EG         QKVGEL  N+QEII  GGLE
Sbjct: 735 SDKTDSKQLTRRTGWTLTWDVRRSQIEIQEGP--DGPKWTQKVGELPPNVQEIIALGGLE 792

Query: 687 GWVKSQL 693
            WVK+ +
Sbjct: 793 KWVKNSI 799
>ref|XP_717326.1| homoaconitase [Candida albicans SC5314]
 ref|XP_717250.1| homoaconitase [Candida albicans SC5314]
 sp|Q5A644|LYS4_CANAL Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|EAK98277.1| potential homoaconitase [Candida albicans SC5314]
 gb|EAK98354.1| potential homoaconitase [Candida albicans SC5314]
          Length = 684

 Score =  892 bits (2305), Expect = 0.0,   Method: Composition-based stats.
 Identities = 484/695 (69%), Positives = 567/695 (81%), Gaps = 18/695 (2%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNL-PEGKVVHSGDYVSIKPAHCMSHDN 59
           MLR     RSF ++   L+GQNLTEKIVQ YAV L P  K V+SGDYV+IKPAHCMSHDN
Sbjct: 2   MLR----FRSFSTTTHLLRGQNLTEKIVQKYAVGLQPSSKKVYSGDYVTIKPAHCMSHDN 57

Query: 60  SWPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGR 119
           SWPVA KFM LGA+K+K+  QIV TLDHD+QNKSE+NLTKY NIE FAK   ID YPAGR
Sbjct: 58  SWPVATKFMNLGASKVKDNRQIVCTLDHDVQNKSEQNLTKYTNIEKFAKSQGIDFYPAGR 117

Query: 120 GIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPV 179
           GIGHQIMIEEGYAFPLN+TVASDSHSNTYGG+G+LGTPIVRTDAA+IWATGQTWWQIPPV
Sbjct: 118 GIGHQIMIEEGYAFPLNLTVASDSHSNTYGGIGALGTPIVRTDAASIWATGQTWWQIPPV 177

Query: 180 AQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGD-SLNALPIDHRLTIANMTT 238
           A+VEL GQLP+GV+GKDIIVALCG+FNND+VLNHAIEF GD +++ LPID+RLTIANMTT
Sbjct: 178 AKVELIGQLPKGVTGKDIIVALCGIFNNDEVLNHAIEFVGDDAISKLPIDYRLTIANMTT 237

Query: 239 EWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKK 298
           EWGALSGLFPVD+TL+++Y+NRL+KL   +HPRIN +TI  L        +D DA YAK 
Sbjct: 238 EWGALSGLFPVDETLVEFYQNRLKKLNKPDHPRINNQTIDQLIN--NKLTSDNDAVYAKH 295

Query: 299 LIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPT 358
           L IDL++L+ Y+SGPNSVK+SN++ DLSQQ+I INKAYLVSCTNSRLSD+Q+AAD++   
Sbjct: 296 LQIDLSSLSPYISGPNSVKISNSLYDLSQQNIAINKAYLVSCTNSRLSDIQAAADII--- 352

Query: 359 GDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLL 418
               K +KV P VEFYVAAASS ++ DA +SGAW+ +L AG  PLP+GCGPCIGLG GLL
Sbjct: 353 ----KGHKVNPNVEFYVAAASSLVQKDAEQSGAWQTILDAGAKPLPAGCGPCIGLGTGLL 408

Query: 419 EPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVK 478
           + GEVGISATNRNFKGRMGSKDALAYLASP VVAASAVLGKI  P E+          + 
Sbjct: 409 KDGEVGISATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGGPEELNGEPVKQAPRII 468

Query: 479 TEIIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQD 538
             I        E  + +E    S++IL GFP+   GEL+LC+ADNINTDGIYPGKYTYQD
Sbjct: 469 KSIETESNSANEAESTSEEASGSIDILPGFPQSIEGELILCNADNINTDGIYPGKYTYQD 528

Query: 539 DVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGS 598
           D+ KE+MA+VCMENYD++F +K  PGDI++SG+NFGTGSSREQAAT +LA+G+ L+V+GS
Sbjct: 529 DITKEQMAKVCMENYDSQFYSKTKPGDIIISGYNFGTGSSREQAATCILARGMKLIVAGS 588

Query: 599 FGNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGS 658
           FGNIFSRNSINNALLTLEIP LI KLR++Y+G   ELT RTGWFLKWDV  A+V V +G 
Sbjct: 589 FGNIFSRNSINNALLTLEIPDLINKLRQQYEGND-ELTIRTGWFLKWDVTKAQVTVVDG- 646

Query: 659 LDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            D  +IL QKVGELG NLQ+IIVKGGLEGWVKS+L
Sbjct: 647 -DDNLILTQKVGELGTNLQDIIVKGGLEGWVKSEL 680
>ref|XP_001258433.1| mitochondrial aconitate hydratase, putative [Neosartorya fischeri
           NRRL 181]
 gb|EAW16536.1| mitochondrial aconitate hydratase, putative [Neosartorya fischeri
           NRRL 181]
          Length = 781

 Score =  892 bits (2305), Expect = 0.0,   Method: Composition-based stats.
 Identities = 164/762 (21%), Positives = 285/762 (37%), Gaps = 97/762 (12%)

Query: 2   LRSTTFTRSFHSSRAWL-KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +     + +    R  L +     EK++ S+  +    ++     Y+ ++P      D +
Sbjct: 42  INYKKMSENLDIVRRRLQRPLTYAEKVLYSHLDDPHGQEIERGKSYLKLRPDRVACQDAT 101

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G   +  P+ +    DH I+            +E N   Y  + +   K
Sbjct: 102 AQMAILQFMSAGMPSVATPTTV--HCDHLIEAQVGGDKDLARANEINKEVYDFLASATAK 159

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  YAFP  + + +DSH+   GGL      +   DA  + A 
Sbjct: 160 YNIGFWKPGSGIIHQIVLEN-YAFPGGLMIGTDSHTPNAGGLAMAAIGVGGADAVDVMAG 218

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V+L G++    + KDII+ + GL          IE+ G  + +L    
Sbjct: 219 LPWELKAPKVIGVKLTGEMSGWTTPKDIILKVAGLLTVKGGTGAIIEYHGPGVTSLSCTG 278

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + +FP +  + D+ K   ++                  E AK  + 
Sbjct: 279 MGTICNMGAEIGATTSMFPFNDRMYDYLKATKRQHIG-----------DFSREYAKELRE 327

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +    +         ++    + SCTNS
Sbjct: 328 DEGAEYDQLIEINLSELEPHINGPFTPDLATPISKFKEAVETNKWPEELKVGLIGSCTNS 387

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     +      +     F V   S +I A   + G  + L + G + L
Sbjct: 388 SYEDMSRAASIARDALNHG----LKAKSLFTVTPGSEQIRATIERDGQLQTLEEFGGVIL 443

Query: 404 PSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    IS+ NRNF GR   +    A++ASP +V A  V G 
Sbjct: 444 ANACGPCIGQWDRKDVKKGEPNSIISSYNRNFTGRNDANPATHAFVASPDLVVAMTVAGT 503

Query: 460 I-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           +               E      +   +P   +   +      P     VN         
Sbjct: 504 LKFNPLTDKLKDKDGNEFLLQPPTGEGLPAKGYDPGRDTYQAPPTDRASVNVAVSPTSDR 563

Query: 502 VEILEGFPREFSG-----ELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           +++L GF            +++        D+I+  G +     + D++    +   V  
Sbjct: 564 LQLLAGFEPWDGKDANGIPILIKCQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAVNA 623

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN  A        G                   +V+  +N+G GSSRE AA      G  
Sbjct: 624 ENGKANSVKNKFTGEYDAVPATARDYKARGIKWVVIGDWNYGEGSSREHAALEPRHLGGL 683

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    PA   K+  +            G  +       
Sbjct: 684 AIITRSFARIHETNLKKQGMLPLTFADPADYDKINPEDTVDLLCTQLEVGKPMTL----- 738

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
           +V   +GS    + L        ++  E    G     +  +
Sbjct: 739 RVHPKDGSAPFDISLNHT---FNESQIEWFKDGSALNTMARK 777
>ref|XP_001268345.1| mitochondrial aconitate hydratase, putative [Aspergillus clavatus
           NRRL 1]
 gb|EAW06919.1| mitochondrial aconitate hydratase, putative [Aspergillus clavatus
           NRRL 1]
          Length = 780

 Score =  892 bits (2305), Expect = 0.0,   Method: Composition-based stats.
 Identities = 165/762 (21%), Positives = 285/762 (37%), Gaps = 97/762 (12%)

Query: 2   LRSTTFTRSFHSSR-AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +     + +    R    +     EKI+ S+  +    ++     Y+ ++P      D +
Sbjct: 42  INYKKMSENLDIVRQRLQRPLTYAEKILYSHLDDPHGQEIERGKSYLKLRPDRVACQDAT 101

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G   +  P+ +    DH I+            +E N   Y  + +   K
Sbjct: 102 AQMAILQFMSAGMPSVATPTTV--HCDHLIEAQVGGDKDLARANEINKEVYDFLASSTAK 159

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  YAFP  + + +DSH+   GGL      +   DA  + A 
Sbjct: 160 YNIGFWKPGSGIIHQIVLEN-YAFPGGLMIGTDSHTPNAGGLAMAAIGVGGADAVDVMAG 218

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V+L G++    + KDII+ + GL          IE+ G  +N+L    
Sbjct: 219 LPWELKAPKVIGVKLTGEMSGWTTPKDIILKVAGLLTVKGGTGAIIEYHGPGVNSLSCTG 278

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + LFP +  + D+ K   ++                    AK  + 
Sbjct: 279 MGTICNMGAEIGATTSLFPFNDRMYDYLKATKRQQIG-----------DFSRAYAKELRE 327

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +    +         ++    + SCTNS
Sbjct: 328 DEGAEYDQLVEINLSELEPHINGPFTPDLATPISKFKEAVETNKWPEELKVGLIGSCTNS 387

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     D      +     F V   S +I A   + G  + L + G + L
Sbjct: 388 SYEDMSRAASIARDALDHG----IKAKSLFTVTPGSEQIRATIERDGQLQTLEEFGGVIL 443

Query: 404 PSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    IS+ NRNF GR   +    A++ASP +V A  V G 
Sbjct: 444 ANACGPCIGQWDRKDVKKGEANSIISSYNRNFTGRNDANPATHAFVASPDLVVAMTVAGT 503

Query: 460 I-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           +               E      S   +P   +   +      P     VN         
Sbjct: 504 LKFNPLTDKLKDKDGNEFLLKAPSGEGLPANGYDPGRDTYQAPPADRASVNVAVSPTSDR 563

Query: 502 VEILEGFPREFSG-----ELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           +++L GF            +++        D+I+  G +     + D++    +   +  
Sbjct: 564 LQLLAGFEAWDGKDANGIPILIKCQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAINE 623

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN  A        G                   +V+  +N+G GSSRE AA      G  
Sbjct: 624 ENGKANSVKNKFTGEYDAVPATARDYKARGVKWVVIGDWNYGEGSSREHAALEPRHLGGL 683

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    PA   +++ +            G  +       
Sbjct: 684 AIITRSFARIHETNLKKQGMLPLTFAEPADYDRIKPEDTVDLLCTELEVGKPMTL----- 738

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
           +V   +GS    + L        ++  E    G     +  +
Sbjct: 739 RVHPKDGSAAFDITLNHT---FNESQIEWFKDGSALNTMARK 777
>ref|XP_001822935.1| hypothetical protein [Aspergillus oryzae RIB40]
 sp|Q2U9G3|LYS4_ASPOR Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 dbj|BAE61802.1| unnamed protein product [Aspergillus oryzae]
          Length = 775

 Score =  892 bits (2305), Expect = 0.0,   Method: Composition-based stats.
 Identities = 419/729 (57%), Positives = 500/729 (68%), Gaps = 43/729 (5%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S     S  +SRA    Q LTEKIVQ Y+V L + K V SGDYV+I P  CM+HDNSWPV
Sbjct: 49  SAAVYSSLQASRAV--PQTLTEKIVQKYSVGLAKDKFVKSGDYVTISPHRCMTHDNSWPV 106

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GATK+ +P QIV TLDHD+QNKSEKNL KY+ IE+FAK   ++ YPAGRGIGH
Sbjct: 107 ALKFMSIGATKLHDPKQIVMTLDHDVQNKSEKNLQKYRQIEDFAKHQGVEFYPAGRGIGH 166

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           Q+M+EEGYA+P  + VASDSHSN YGG+G LGTPIVRTD A+IWATG+TWWQIPPVA+V 
Sbjct: 167 QVMVEEGYAWPGTLVVASDSHSNMYGGVGCLGTPIVRTDGASIWATGKTWWQIPPVAKVT 226

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWG 241
           L G LP GV+GKD+IVALCGLF+ D VLNHAIEFTG   ++ +L +D RLTIANMTTEWG
Sbjct: 227 LTGVLPPGVTGKDVIVALCGLFDKDDVLNHAIEFTGPEETMRSLSVDARLTIANMTTEWG 286

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNH-------PRINPKTIRALEEKAKIPKADKDAH 294
           ALSGLFP+D  L  W K +                   +       +  A    ADK A 
Sbjct: 287 ALSGLFPIDNVLKGWLKGKATTAAMGLAEGPFKTLAPQHFTHPLLEQLFANPLTADKGAK 346

Query: 295 YAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADV 354
           YAK+L +DL+TL+ YVSGPNSVKV+  ++DL  Q+IK+NKAYLVSCTNSR SD+ +AA V
Sbjct: 347 YAKELFLDLSTLSPYVSGPNSVKVATPLKDLEAQNIKVNKAYLVSCTNSRASDIAAAARV 406

Query: 355 VCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIG 412
                + N     K+A GVEFYVAAAS   +  A ++G W+ LL AG  PL  GC  CIG
Sbjct: 407 FKEAAEKNGGKVPKIADGVEFYVAAASIPEQLAAEEAGDWQALLDAGATPLLPGCAQCIG 466

Query: 413 LGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEI 472
           LG GLLE GEVGISA+NRNFKGRMGS DA AYL SP VVAASA+ GK+S P    +   +
Sbjct: 467 LGTGLLEAGEVGISASNRNFKGRMGSTDAKAYLGSPEVVAASALTGKLSGPGWYQAPEGL 526

Query: 473 ------PFSGVKTE---------------IIENPVVEEEVNAQTEAPK-----QSVEILE 506
                    G++ E                I+N V + E     E  +        E+  
Sbjct: 527 TEVVRGEGDGIREEDRMLTAEQALEKLIGQIDNLVADGEKQFAPEESEESSGDSLTEVYP 586

Query: 507 GFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDI 566
           GFP   SGE+V CDADNINTDGIYPGKYTYQDDV +E MAQVCM NYDA+F +    GDI
Sbjct: 587 GFPERVSGEIVFCDADNINTDGIYPGKYTYQDDVSQETMAQVCMSNYDAQFSSIAKEGDI 646

Query: 567 VVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLRE 626
           +V+GFNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ LE+P LI +LRE
Sbjct: 647 LVTGFNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGLEVPRLINRLRE 706

Query: 627 KY--QGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGG 684
            +  +G+ K LTRRTGW L WDV  +++ V EG          +VGEL  N+QEII KGG
Sbjct: 707 SFSGEGSDKSLTRRTGWTLTWDVRRSRIEVQEGEN--GPKWTHQVGELPPNVQEIIAKGG 764

Query: 685 LEGWVKSQL 693
           LE WVK+++
Sbjct: 765 LEKWVKNEI 773
>emb|CAD60751.1| unnamed protein product [Podospora anserina]
 emb|CAP49271.1| unnamed protein product [Podospora anserina]
          Length = 787

 Score =  891 bits (2304), Expect = 0.0,   Method: Composition-based stats.
 Identities = 158/762 (20%), Positives = 280/762 (36%), Gaps = 98/762 (12%)

Query: 2   LRSTTFTRSFHSSR-AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +     + +    R    +     EKI+ S+  +    ++     Y+ ++P      D +
Sbjct: 50  INYKKMSENLAIVRSRLNRPLAYAEKILYSHLDDPHGQEIERGVSYLRLRPDRVACQDAT 109

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDI--QNKSEK--------NLTKYKNIENFAKK 109
             +A L+FM  G   + NP+ +    DH I  Q   EK        N   Y  + +   K
Sbjct: 110 AQMAILQFMSAGMPSVANPTTV--HCDHLIEAQQGGEKDLARAVGINKEVYDFLASACAK 167

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  YAFP  + + +DSH+   GGLG     +   DA  + A 
Sbjct: 168 YNIGFWKPGSGIIHQILLEN-YAFPGGLLIGTDSHTPNAGGLGMAAIGVGGADAVDVMAN 226

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V+L G L    S KDII+ + G+          +E+ G  +++L    
Sbjct: 227 LPWELKAPKVIGVKLTGSLSGWTSPKDIILKVAGILTVKGGTGAIVEYFGPGVDSLSATG 286

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + LFP +  + D+ K   +                     AK  + 
Sbjct: 287 MGTICNMGAEIGATTSLFPFNDRMYDYLKATKRTEIG-----------DFARSYAKELRQ 335

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D  A Y + + I+L+ L  +++GP +  ++  +   ++         ++    + SCTNS
Sbjct: 336 DDGAEYDQLIEINLSELEPHINGPFTPDLATPISKFAEAAKANNWPDEVKVGLIGSCTNS 395

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     +      +     F V   S +I A   + G  +   + G + L
Sbjct: 396 SYEDMSRAASIARDALNHG----IKSKALFTVTPGSEQIRATIARDGQLQTFEEFGGVVL 451

Query: 404 PSGCGPCIGLGAGL-LEPGEVG--ISATNRNFKGRM-GSKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    IS+ NRNF GR  G+    +++ SP +V A ++ G 
Sbjct: 452 ANACGPCIGQWDRQDVKKGEANSIISSYNRNFTGRNDGNPATHSFVTSPDLVVAMSIAGS 511

Query: 460 IS-----------SPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           +S              +      + + +P   +   +      P     V  Q       
Sbjct: 512 LSFNPLTDTLKDKDGKDFKLSPPTGNGLPERGYDPGQDTYQAPPKDRANVTVQVSPTSDR 571

Query: 502 VEILEGFPREF-----SGELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           +++L  F            +++        D+I+  G +     + D++    +   +  
Sbjct: 572 LQLLSPFNAWDGKDATDMPILIKAQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAINA 631

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
            N +A        G                   +V+  +N+G GSSRE AA      G  
Sbjct: 632 ANGEANKIKNFTTGEWDAVPAVARDYKAKGIRWVVIGDWNYGEGSSREHAALEPRHLGGL 691

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    PA   ++    +          G          
Sbjct: 692 AIITRSFARIHETNLKKQGMLPLTFSDPADYDRINPDDKVDILCTELAVGKP-------- 743

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
            + +     +G            +   E    G     +  +
Sbjct: 744 -ITLRVKPANGEAFEIPLSHTFNEAQIEWFKNGSALNTMAKK 784
>ref|XP_359935.2| hypothetical protein MGG_04842 [Magnaporthe grisea 70-15]
 gb|EDJ95590.1| hypothetical protein MGG_04842 [Magnaporthe grisea 70-15]
          Length = 776

 Score =  889 bits (2298), Expect = 0.0,   Method: Composition-based stats.
 Identities = 414/722 (57%), Positives = 500/722 (69%), Gaps = 39/722 (5%)

Query: 7   FTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALK 66
              SF +  +    Q LTEKIVQ Y+V L  GK V SGDYV++ P HCM+HDNSWPVALK
Sbjct: 57  LFSSFQTPPSN--PQTLTEKIVQRYSVGLAPGKKVKSGDYVTLSPHHCMTHDNSWPVALK 114

Query: 67  FMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIM 126
           FM +GA+KI +  Q+V TLDHD+QNKSE NL KY+ IE FAK H +D YPAGRGIGHQIM
Sbjct: 115 FMSIGASKIHDNRQVVMTLDHDVQNKSESNLKKYRQIEEFAKTHGVDFYPAGRGIGHQIM 174

Query: 127 IEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKG 186
           +EEGYA+P  +TVASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V L G
Sbjct: 175 VEEGYAWPGTVTVASDSHSNMYGGVGCLGTPMVRTDAASIWATGKTWWQIPPIAKVTLTG 234

Query: 187 QLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALS 244
            LP GV+GKD+IVALCGLFNND+VLNHAIEFTG  +++ ++P+D RL IANMTTEWGAL+
Sbjct: 235 VLPPGVTGKDVIVALCGLFNNDEVLNHAIEFTGSEETMRSIPVDDRLAIANMTTEWGALA 294

Query: 245 GLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLA 304
           GLFP+D  L  W + +          R      +  E      +AD  A YAK L ++L+
Sbjct: 295 GLFPIDSVLQGWLRGKATTSAMFGGGRDVFTHEKIEELIQNQLRADPGAKYAKSLYLNLS 354

Query: 305 TLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKV 364
           TL  +V+GPNSVKV+  ++DL  +DIK+NKAYLVSCTNSR SD+ +AA V        K 
Sbjct: 355 TLAPFVAGPNSVKVATPLKDLEAKDIKVNKAYLVSCTNSRASDIAAAAKVFKEASKDGKP 414

Query: 365 NKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVG 424
             +APGV+FY+ AAS+  +A A ++G W+ LL AG   LP+GCGPCIGLG GLLEPGEVG
Sbjct: 415 AVIAPGVKFYIGAASTLEQAAAEEAGDWKVLLDAGAQALPAGCGPCIGLGTGLLEPGEVG 474

Query: 425 ISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFS--------- 475
           ISA+NRNFKGRMGS DA AYLAS  VVAASA+ GKI+ P        +            
Sbjct: 475 ISASNRNFKGRMGSTDAKAYLASQEVVAASALKGKIAGPGWYEKPEGVEKVIIGEGNGDA 534

Query: 476 ----------------GVKTEIIENPVV---EEEVNAQTEAPKQSVEILEGFPREFSGEL 516
                           G    +I +           A++   +   EIL GFP    GE+
Sbjct: 535 VHDKAVSIEEALAKLLGEAESMISDAEQNLGGSSQQAESAEEETLTEILPGFPERVEGEI 594

Query: 517 VLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTG 576
           V CDADNINTDGIYPGKYTYQD+V  EKMA+VCMENYD EF      GD++V+GFNFG G
Sbjct: 595 VFCDADNINTDGIYPGKYTYQDNVSTEKMAEVCMENYDKEFGKVAREGDVLVAGFNFGCG 654

Query: 577 SSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQG-----A 631
           SSREQAATA+LAK I LVV+GSFGNIFSRNSINNAL+ +E+P L+++LRE + G      
Sbjct: 655 SSREQAATAILAKRIPLVVAGSFGNIFSRNSINNALMGVEVPRLVERLRETFGGKEQGEE 714

Query: 632 PKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
            K LTRRTGW   WDV  +KV VTEGS  G     QKVGEL  N+QEII +GGLE WVKS
Sbjct: 715 NKALTRRTGWTFVWDVRRSKVTVTEGS--GGETWSQKVGELPPNVQEIIARGGLEKWVKS 772

Query: 692 QL 693
           Q+
Sbjct: 773 QI 774
>ref|XP_001911427.1| unnamed protein product [Podospora anserina]
 emb|CAP73252.1| unnamed protein product [Podospora anserina]
          Length = 781

 Score =  889 bits (2298), Expect = 0.0,   Method: Composition-based stats.
 Identities = 420/726 (57%), Positives = 501/726 (69%), Gaps = 39/726 (5%)

Query: 5   TTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA 64
                   +  A    Q LTEKIVQ Y+V L  GK V SGDYV++ P HCM+HDNSWPVA
Sbjct: 56  ENAAPLPSAKSATQTPQTLTEKIVQRYSVGLAPGKTVKSGDYVTLAPHHCMTHDNSWPVA 115

Query: 65  LKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQ 124
           +KFM +GA+KI +  Q+V TLDHD+QNKSE NL KY+ IE FA KH +D YPAGRGIGHQ
Sbjct: 116 MKFMSIGASKIHDNRQVVMTLDHDVQNKSEANLKKYRQIEEFAGKHGVDFYPAGRGIGHQ 175

Query: 125 IMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVEL 184
           IM+EEGYA+P  +TVASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPP+A+V L
Sbjct: 176 IMVEEGYAWPGTVTVASDSHSNMYGGVGCLGTPMVRTDAASIWATGRTWWQIPPIAKVTL 235

Query: 185 KGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGA 242
            G LP GV+GKD+IVALCGLFNND VLNHAIEFTG  +++ +L ID RL IANMTTEWGA
Sbjct: 236 TGILPPGVTGKDVIVALCGLFNNDDVLNHAIEFTGSEETMRSLSIDDRLAIANMTTEWGA 295

Query: 243 LSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEK--AKIPKADKDAHYAKKLI 300
           LSGLFP+D  L  W + +       N      K      +       +AD  A YAK L 
Sbjct: 296 LSGLFPIDSVLQQWLRAKATTAAMFNPEAAKGKFTHEKIDDLINNQLRADPGATYAKSLY 355

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           ++L+TL+ +V+GPNSVKV+  ++DL  QDIK+NKAYLVSCTNSR SD+ +AA+V      
Sbjct: 356 LNLSTLSPFVAGPNSVKVATPLKDLEAQDIKLNKAYLVSCTNSRASDIAAAANVFREVAK 415

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
              + KVA GV+FY+AAAS+  +A A ++G W+ LL AG  PLPSGCGPCIGLG GLLEP
Sbjct: 416 DGVIPKVAEGVKFYIAAASTLEQAAAEEAGDWQVLLAAGAEPLPSGCGPCIGLGTGLLEP 475

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGV--- 477
           GEVGISA+NRNFKGRMGS DA AYLASP VVAASA+ GKI+ P        +    +   
Sbjct: 476 GEVGISASNRNFKGRMGSTDAKAYLASPEVVAASALKGKIAGPGWYQKPEGVEKVIIGEG 535

Query: 478 ----------------------KTEIIENPV-----VEEEVNAQTEAPKQSVEILEGFPR 510
                                    +I +        E          +   EIL GFP 
Sbjct: 536 NGDVVQDKAMSIEEALDKLIAQADSMIASAEKEFSGDEAAAAESAAEAETLTEILPGFPE 595

Query: 511 EFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVHPGDIVVSG 570
           +  GE+V CDADNINTDGIYPGKYTYQD+V  EKMA+VCMENYD EF      GDI+VSG
Sbjct: 596 KIEGEIVFCDADNINTDGIYPGKYTYQDNVTTEKMAEVCMENYDKEFGQVAKEGDILVSG 655

Query: 571 FNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIKKLREKYQG 630
           FNFG GSSREQAATA+LAK I LVVSGSFGNIFSRNSINNAL+ +E+P L+++LRE ++ 
Sbjct: 656 FNFGCGSSREQAATAILAKKIPLVVSGSFGNIFSRNSINNALMGVEVPRLVQRLRETFKA 715

Query: 631 A---PKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEG 687
                K LTRRTGW L WDV  +KV VTEG  +G     QKVGEL  N+QEII +GGLE 
Sbjct: 716 DGEGNKVLTRRTGWKLVWDVRRSKVTVTEG--EGGQQWSQKVGELPPNVQEIIARGGLEK 773

Query: 688 WVKSQL 693
           WVKSQ+
Sbjct: 774 WVKSQI 779
>gb|AAC61778.1| aconitase [Aspergillus terreus]
          Length = 778

 Score =  889 bits (2298), Expect = 0.0,   Method: Composition-based stats.
 Identities = 164/762 (21%), Positives = 281/762 (36%), Gaps = 98/762 (12%)

Query: 2   LRSTTFTRSFHSSRAWL-KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +     + +    R  L +     EK++ S+  +     +     Y+ ++P      D +
Sbjct: 40  INYKKMSENLDIVRRRLSRPLTYAEKVLYSHLDDPHGQDIERGVSYLKLRPDRVACQDAT 99

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G   +  P+ +    DH I+            +E N   Y  +     K
Sbjct: 100 AQMAILQFMSAGMPSVATPTTV--HCDHLIEAQVGGEKDLARANEINKEVYDFLATATAK 157

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  YAFP  + + +DSH+   GGL      +   DA  + A 
Sbjct: 158 YNIGFWKPGSGIIHQIVLEN-YAFPGGLMIGTDSHTPNAGGLAMAAIGVGGADAVDVMAG 216

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V+L G++    + KDII+ + GL          IE+ G  +N+L    
Sbjct: 217 LPWELKAPKVIGVKLTGEMSGWTTPKDIILKVAGLLTVKGGTGAIIEYHGPGVNSLSCTG 276

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + +FP +  + D+ K   ++                    AK  + 
Sbjct: 277 MGTICNMGAEIGATTSMFPFNDRMYDYLKATKRQHIG-----------EFARSYAKELRE 325

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +    +         ++    + SCTNS
Sbjct: 326 DEGAEYDQLIEINLSELEPHINGPFTPDLATPISKFKEAVDANGWPEELKVGLIGSCTNS 385

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     +      V     F V   S +I A   + G  + L + G + L
Sbjct: 386 SYEDMSRAASIARDALNHG----VKSKSLFTVTPGSEQIRATIERDGQLQTLEEFGGVIL 441

Query: 404 PSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    IS+ NRNF GR   +    A++ASP +V A  V G 
Sbjct: 442 ANACGPCIGQWDRKDVKKGEPNSIISSYNRNFTGRNDANPATHAFVASPDLVVAMCVAGT 501

Query: 460 I-----------SSPAEV----LSTSEIPFSGVK---TEIIENPVVEEEVNAQTEAPKQS 501
           +               E      S   +P  G           P     +N         
Sbjct: 502 LKFNPLTDTVKDKDGKEFKLAPPSGDGLPSKGYDAGRNTYQAPPQDRASINVAVSPTSDR 561

Query: 502 VEILEGFPREFSG-----ELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           +++L GF            +++        D+I+  G +     + D++    +   V  
Sbjct: 562 LQLLAGFEAWDGKDANGIPILIKCQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAVNA 621

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN +A        G                   +V+  +N+G GSSRE AA      G  
Sbjct: 622 ENGEANKVKNKFTGEYGAVPATARDYKARGVKWVVIGDWNYGEGSSREHAALEPRHLGGL 681

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    PA   K++ +            G  +   V   
Sbjct: 682 AIITRSFARIHETNLKKQGMLPLTFADPADYDKIQPEDTVDLLCTELEVGKPMTLRV--- 738

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
                    +G     +      ++  E    G     +  +
Sbjct: 739 ------HPKNGSTFDVKLNHTFNESQIEWFKDGSALNTMARK 774
>gb|ABH10644.1| aconitase [Coccidioides posadasii]
          Length = 784

 Score =  888 bits (2295), Expect = 0.0,   Method: Composition-based stats.
 Identities = 158/762 (20%), Positives = 280/762 (36%), Gaps = 98/762 (12%)

Query: 2   LRSTTFTRSFHSSRAWL-KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +       +    RA L +     EKI+ S+  +    ++     Y+ ++P      D +
Sbjct: 48  INYKKMAENLDIVRARLNRPLTYAEKILYSHLDDPHGQEIERGKSYLKLRPDRVACQDAT 107

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G   +  P+ +    DH I+            +E N   Y  + +   K
Sbjct: 108 AQMAILQFMSAGMPSVATPTTV--HCDHLIEAQLGGDKDLARANEINKEVYNFLSSSCAK 165

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  Y FP  + + +DSH+   GGLG     +   DA  + A 
Sbjct: 166 YNIGFWKPGSGIIHQILLEN-YCFPGGLMIGTDSHTPNGGGLGMAAIGVGGADAVDVMAG 224

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V+L G+L    + KDII+ + G+          IE+ G  +++L    
Sbjct: 225 LPWELKAPKVIGVKLTGELSGWTAPKDIILKVAGILTVKGGTGAIIEYHGPGVDSLSCTG 284

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + +FP ++ + D+ K   ++                    +K  + 
Sbjct: 285 MGTICNMGAEIGATTSVFPFNERMYDYLKATKRQAIG-----------DFARTYSKGLRE 333

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +    +         ++    + SCTNS
Sbjct: 334 DEGAEYDQLIEINLSELEPHINGPFTPDLATPISKFKEAVKANGWPEELKVGLIGSCTNS 393

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     +      +     F V   S +I A   + G  + L + G + L
Sbjct: 394 SYEDMSRAASIARDALNHG----LKAKSLFTVTPGSEQIRATIERDGQLKTLEEFGGVIL 449

Query: 404 PSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    IS+ NRNF GR   +    A++ SP +V A  V G 
Sbjct: 450 ANACGPCIGQWDRKDVKKGEKNSIISSYNRNFTGRNDANPATHAFVTSPDLVVALTVAGT 509

Query: 460 I-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           +           +   E      +   +P   +   +      P     +          
Sbjct: 510 LNFNPLTDTLKGADGKEFKLAPPTGEGLPARGYDPGRDTYQAPPQDRASIQVAVSPSSDR 569

Query: 502 VEILEGFPREF----SGELVL------CDADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           +++L+ F         G  +L         D+I+  G +     + D++    +   V  
Sbjct: 570 LQVLQPFKPWDGKDAKGIPILIKAQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAVNA 629

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN +         G                   +V+  +N+G GSSRE AA      G  
Sbjct: 630 ENGETNNVKNFQTGEYAGVPDTARAYKAKGIKWVVIGDWNYGEGSSREHAALEPRHLGGL 689

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    PA   ++               G          
Sbjct: 690 AIITRSFARIHETNLKKQGMLPLTFTDPADYDRIPPTATVDLMCTELAVGKP-------- 741

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
            + +     DG            ++  +    G     +  Q
Sbjct: 742 -ITLRVHPKDGKPFDVSLSHTFNESQLQWFKDGSALNTMAKQ 782
>ref|XP_001247958.1| aconitate hydratase, mitochondrial precursor [Coccidioides immitis
           RS]
 gb|EAS36375.1| aconitate hydratase, mitochondrial precursor [Coccidioides immitis
           RS]
          Length = 784

 Score =  888 bits (2295), Expect = 0.0,   Method: Composition-based stats.
 Identities = 158/762 (20%), Positives = 280/762 (36%), Gaps = 98/762 (12%)

Query: 2   LRSTTFTRSFHSSRAWL-KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +       +    RA L +     EKI+ S+  +    ++     Y+ ++P      D +
Sbjct: 48  INYKKMAENLDIVRARLNRPLTYAEKILYSHLDDPHGQEIERGKSYLKLRPDRVACQDAT 107

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G   +  P+ +    DH I+            +E N   Y  + +   K
Sbjct: 108 AQMAILQFMSAGMPSVATPTTV--HCDHLIEAQLGGDKDLARANEINKEVYNFLSSSCAK 165

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  Y FP  + + +DSH+   GGLG     +   DA  + A 
Sbjct: 166 YNIGFWKPGSGIIHQILLEN-YCFPGGLMIGTDSHTPNGGGLGMAAIGVGGADAVDVMAG 224

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V+L G+L    + KDII+ + G+          IE+ G  +++L    
Sbjct: 225 LPWELKAPKVIGVKLTGELSGWTAPKDIILKVAGILTVKGGTGAIIEYHGPGVDSLSCTG 284

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + +FP ++ + D+ K   ++                    +K  + 
Sbjct: 285 MGTICNMGAEIGATTSVFPFNERMYDYLKATKRQAIG-----------DFARTYSKGLRE 333

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +    +         ++    + SCTNS
Sbjct: 334 DEGAEYDQLIEINLSELEPHINGPFTPDLATPISKFKEAVKANGWPEELKVGLIGSCTNS 393

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     +      +     F V   S +I A   + G  + L + G + L
Sbjct: 394 SYEDMSRAASIARDALNHG----LKAKSLFTVTPGSEQIRATIERDGQLKTLEEFGGVIL 449

Query: 404 PSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    IS+ NRNF GR   +    A++ SP +V A  V G 
Sbjct: 450 ANACGPCIGQWDRKDVKKGEKNSIISSYNRNFTGRNDANPATHAFVTSPDLVVALTVAGT 509

Query: 460 I-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           +           +   E      +   +P   +   +      P     +          
Sbjct: 510 LNFNPLTDTLKGADGKEFKLAPPTGEGLPARGYDPGRDTYQAPPQDRASIQVDVSPSSDR 569

Query: 502 VEILEGFPREF----SGELVL------CDADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           +++L+ F         G  +L         D+I+  G +     + D++    +   V  
Sbjct: 570 LQVLQPFKPWDGKDAKGIPILIKAQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAVNA 629

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN +         G                   +V+  +N+G GSSRE AA      G  
Sbjct: 630 ENGETNNVKNFQTGEYAGVPDTARAYKAKGIKWVVIGDWNYGEGSSREHAALEPRHLGGL 689

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    PA   ++               G          
Sbjct: 690 AIITRSFARIHETNLKKQGMLPLTFTDPADYDRIPPTATVDLMCTELAVGKP-------- 741

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
            + +     DG            ++  +    G     +  Q
Sbjct: 742 -ITLRVHPKDGKPFDVSLSHTFNESQLQWFKDGSALNTMAKQ 782
>ref|XP_001393157.1| hypothetical protein An08g10530 [Aspergillus niger]
 emb|CAK45726.1| unnamed protein product [Aspergillus niger]
          Length = 777

 Score =  888 bits (2295), Expect = 0.0,   Method: Composition-based stats.
 Identities = 169/762 (22%), Positives = 290/762 (38%), Gaps = 98/762 (12%)

Query: 2   LRSTTFTRSFHSSRAWL-KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +     + +    R  L +     EK++ S+  +    ++     Y+ ++P      D +
Sbjct: 40  INYKKMSENLDIVRRRLSRPLTYAEKVLYSHLDDPHGQEIERGSSYLKLRPDRVACQDAT 99

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G   +  P+ +    DH I+            ++ N   Y  + +   K
Sbjct: 100 AQMAILQFMSAGMPSVATPTTV--HCDHLIEAQVGGDKDLARANDINKEVYDFLASATAK 157

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  YAFP  + + +DSH+   GGL +    +   DA  + A 
Sbjct: 158 YNIGFWKPGSGIIHQIVLEN-YAFPGGLMIGTDSHTPNAGGLATAAIGVGGADAVDVMAG 216

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V+L GQ+    + KDII+ + GL          IE+ G  +N+L    
Sbjct: 217 LPWELKAPKVIGVKLTGQMSGWTTPKDIILKVAGLLTVKGGTGAIIEYHGPGVNSLSCTG 276

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + +FP +  + D+ K   ++   N              E AK  + 
Sbjct: 277 MATICNMGAEIGATTSMFPFNDRMYDYLKATKRQHIGNFS-----------REYAKELRE 325

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +V+GP +  ++  +    +         ++    + SCTNS
Sbjct: 326 DEGAEYDQLIEINLSELEPHVNGPFTPDLATPISKFKEAVEANKWPEELKVGLIGSCTNS 385

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     D      +     F V   S +I A   + G  + L + G + L
Sbjct: 386 SYEDMSRAASIAQDALDHG----LKSKSLFTVTPGSEQIRATIERDGQLKTLEEYGGVIL 441

Query: 404 PSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    IS+ NRNF GR   +    A++ASP +V A  V G 
Sbjct: 442 ANACGPCIGQWDRKDVKKGEANSIISSYNRNFTGRNDANPATHAFVASPDLVVAMTVAGT 501

Query: 460 I-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           +               E      S   +P   +   +      P   E VN         
Sbjct: 502 LKFNPLTDKLKDKDGKEFMLKPPSGEGLPAQGYDPGRDTYQAPPTNREGVNVAVAPTSDR 561

Query: 502 VEILEGFPREFSG-----ELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           ++IL GF +          +++        D+I+  G +     + D++    +   +  
Sbjct: 562 LQILAGFEKWDGKDATGIPILIKCQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAINA 621

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN +A        G                   +V+  +N+G GSSRE AA      G  
Sbjct: 622 ENGEANKVKNAFTGEYDAVPATARDYKARGVKWVVIGDWNYGEGSSREHAALEPRHLGGL 681

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    PA   K++ + +          G          
Sbjct: 682 AIITRSFARIHETNLKKQGMLPLTFSDPADYDKIKPEDKVDLLCTELEVGKP-------- 733

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
            V +     DG     +      ++  E    G     +  +
Sbjct: 734 -VTLRVHPKDGASFDIKLSHTFNESQIEWFRDGSALNTMARK 774
>ref|XP_460673.1| hypothetical protein DEHA0F08019g [Debaryomyces hansenii CBS767]
 sp|Q6BM98|LYS4_DEBHA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAG89007.1| unnamed protein product [Debaryomyces hansenii CBS767]
          Length = 688

 Score =  887 bits (2293), Expect = 0.0,   Method: Composition-based stats.
 Identities = 475/691 (68%), Positives = 555/691 (80%), Gaps = 18/691 (2%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
             T  R   SS    +GQNLTEKIVQ YAV L + K V SGDYV+IKPAHCMSHDNSWPV
Sbjct: 13  KKTGARCLSSSSILYRGQNLTEKIVQKYAVGLADDKKVFSGDYVTIKPAHCMSHDNSWPV 72

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           A KFMGLGAT + +  QIV TLDHD+QNKSEKNL KY NIENFAK+  ID YPAGRGIGH
Sbjct: 73  ATKFMGLGATNVHDNRQIVCTLDHDVQNKSEKNLEKYHNIENFAKEQGIDFYPAGRGIGH 132

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIMIEEGYA+PLN+TVASDSHSNTYGG+GSLGTPIVRTDAA+IWATGQTWWQIPPVA+VE
Sbjct: 133 QIMIEEGYAYPLNLTVASDSHSNTYGGIGSLGTPIVRTDAASIWATGQTWWQIPPVAKVE 192

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGAL 243
           L GQLP+G +GKDIIVALCG+FNND+VLNHAIEFTG+ +  L +D+RLTIANMTTEWGAL
Sbjct: 193 LVGQLPKGATGKDIIVALCGIFNNDEVLNHAIEFTGEGVKNLSVDYRLTIANMTTEWGAL 252

Query: 244 SGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDL 303
           SGLFPVD+TL+++Y  R++K     HPR+N  T++ L E      +D DA YAK L++DL
Sbjct: 253 SGLFPVDETLVNFYDERVKK-LPQPHPRVNENTVKNLSE--NKVNSDNDAVYAKHLVVDL 309

Query: 304 ATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNK 363
           ++L+ Y+SGPNSVKVS ++ DLS+Q+IKINKAYLVSCTNSRLSD+++AAD++       K
Sbjct: 310 SSLSPYISGPNSVKVSTSLHDLSKQNIKINKAYLVSCTNSRLSDIKAAADII-------K 362

Query: 364 VNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEV 423
            +KVA GVEFYVAAASS ++ DA   GAW+ ++ AG  PLP+GCGPCIGLG GLLE GEV
Sbjct: 363 GHKVAEGVEFYVAAASSNVQKDAEAIGAWQDIIDAGAKPLPAGCGPCIGLGTGLLEDGEV 422

Query: 424 GISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIE 483
           GISATNRNFKGRMGSKDALAYLASP VVAASAVLGKI  P E+             EI+ 
Sbjct: 423 GISATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGGPEELQGNP----VPTNPEIVR 478

Query: 484 NPVVEEEVN-AQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPK 542
           +    E       +A   SV++L+GFP+   GEL+LCDADNINTDGIYPGKYTYQDD+P+
Sbjct: 479 SITSNESTETVDPDASGSSVDVLDGFPQSIEGELILCDADNINTDGIYPGKYTYQDDIPR 538

Query: 543 EKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNI 602
            KMA+VCMENYD+EF+ K   GDI++SG+NFGTGSSREQAATA+LA+ + LVV+GSFGNI
Sbjct: 539 SKMAEVCMENYDSEFKQKTKAGDIIISGYNFGTGSSREQAATAILARDMKLVVAGSFGNI 598

Query: 603 FSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGP 662
           FSRNSINNALLTLEIPALI KLREKY     ELT RTGWFLKWDV   +V V++   +G 
Sbjct: 599 FSRNSINNALLTLEIPALINKLREKY-AQSNELTIRTGWFLKWDVTKNQVTVSDS--EGN 655

Query: 663 VILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           +IL QKVGELG NLQ+IIVKGGLEGWVK+QL
Sbjct: 656 LILTQKVGELGTNLQDIIVKGGLEGWVKAQL 686
>ref|XP_001834931.1| hypothetical protein CC1G_10805 [Coprinopsis cinerea okayama7#130]
 gb|EAU86914.1| hypothetical protein CC1G_10805 [Coprinopsis cinerea okayama7#130]
          Length = 765

 Score =  887 bits (2292), Expect = 0.0,   Method: Composition-based stats.
 Identities = 167/759 (22%), Positives = 287/759 (37%), Gaps = 99/759 (13%)

Query: 2   LRSTTFTRSFHSSR-AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +       +    R    +   L+EKIV  +  N  E ++V    Y+ ++P      D +
Sbjct: 24  INYQRIEDNLAIVRERLNRPLTLSEKIVYGHLDNPHEQEIVRGSSYLKLRPDRVACQDAT 83

Query: 61  WPVAL-KFMGLGATKIKNPSQIVTTLDHDIQN-----KSEK-----NLTKYKNIENFAKK 109
             +AL +FM  G      P+ +    DH I+      K  +     N   Y  +     K
Sbjct: 84  AQMALLQFMSAGMDTAAVPTTV--HCDHLIEAQVGGVKDLERAININKEVYDFLATATAK 141

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           + +  +  G GI HQI++E  YAFP  M + +DSH+   GGLG +   +   DA  + A 
Sbjct: 142 YGLGFWKPGSGIIHQIILEN-YAFPGGMMIGTDSHTPNAGGLGMIACGVGGADAVDVMAG 200

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V L G++    + KD+I+ + G+          +E+ G  + +L    
Sbjct: 201 IPWELKCPKVIGVNLTGKIGGWTTPKDVILKVAGILTVKGGTGAIVEYRGPGVESLSCTG 260

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + +FP ++ +  + K   ++   N   + +              KA
Sbjct: 261 MATICNMGAEIGATTSVFPYNERMAKYLKATNREDIANYARQFSAN-----------LKA 309

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIK------INKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +  L+++  K      I    + SCTNS
Sbjct: 310 DEGAEYDQMIEINLSELEPHINGPFTPDLATPISKLAEEAKKNGWPDEIKVGLIGSCTNS 369

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA++V    D     K     +F V   S ++ A   + G  E    AG I L
Sbjct: 370 SYEDMSRAANIVKQAADHGLSFK----SKFTVTPGSEQVRATIARDGQVEAFENAGAIVL 425

Query: 404 PSGCGPCIGLGAGL-LEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    +++ NRNF GR   +    A++ SP +  A A  G 
Sbjct: 426 ANACGPCIGQWDRQDVKKGEKNTIVTSYNRNFTGRNDANPATHAFVTSPDLTTALAFAGS 485

Query: 460 I-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           +           S          +  E+P   +   +      P     VN   +     
Sbjct: 486 LSFNPLTDTLIGSDGKPFKFESPTGHELPPRGYDPGENTFQAPPADRASVNVAVDPKSDR 545

Query: 502 VEILEGFPREF-----SGELVL-----CDADNINTDGIYPGKYTYQDDVPKE-KMAQVCM 550
           +++L+ F            +++     C  D+I+  G +     + +++ +   +  +  
Sbjct: 546 LQLLKPFAPWDGKEPKDLPILIKVKGKCTTDHISAGGPWLKYRGHLENISQNCLIGAINA 605

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN +A        G                   +V+   N+G GSSRE AA      G  
Sbjct: 606 ENGEANKVKNQITGEYGGVPQTAAYYRDRGVKWVVIGDHNYGEGSSREHAALEPRFLGGL 665

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKEL-TRRTGWFLKWDVAD 649
            ++  SF  I   N     +L L     A   K+R   +     + T   G  +      
Sbjct: 666 AIIVKSFARIHETNLKKQGMLALTFVNEADYDKIRPDDRVDIVGVDTFAPGKNM------ 719

Query: 650 AKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGW 688
               +     DG V          +   E    G     
Sbjct: 720 ---TLVAKHSDGTVDEIPLAHSFNEGQIEWFKAGSALNL 755
>ref|XP_001383888.2| homoaconitase [Pichia stipitis CBS 6054]
 gb|ABN65859.2| homoaconitase [Pichia stipitis CBS 6054]
          Length = 677

 Score =  885 bits (2288), Expect = 0.0,   Method: Composition-based stats.
 Identities = 487/693 (70%), Positives = 562/693 (81%), Gaps = 20/693 (2%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLR     R   +S   L+GQNLTEKIVQ YAVNLP GK V SGDYVSIKPAHCMSHDNS
Sbjct: 1   MLRVNI--RGLATSARLLRGQNLTEKIVQRYAVNLPAGKQVFSGDYVSIKPAHCMSHDNS 58

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WPVA KFMGLGATK+K+  QIV TLDHD+QNKSEKNL KY+NIE FAK+  ID YPAGRG
Sbjct: 59  WPVATKFMGLGATKVKDNRQIVCTLDHDVQNKSEKNLEKYRNIEQFAKEQGIDFYPAGRG 118

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLN+TVASDSHSNTYGG+GSLGTPIVRTDAA+IWATGQTWWQIPPVA
Sbjct: 119 IGHQIMIEEGYAFPLNLTVASDSHSNTYGGVGSLGTPIVRTDAASIWATGQTWWQIPPVA 178

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           +VEL+G+LP GV+GKDIIVALCG FN D+VLNHAIEF GD +  L ID+RLTIANMTTEW
Sbjct: 179 KVELQGKLPAGVTGKDIIVALCGAFNKDEVLNHAIEFVGDGIEHLSIDYRLTIANMTTEW 238

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVD  L+DWY++       + HPR+N KT+ ALE+     ++D DA YAK L+
Sbjct: 239 GALSGLFPVDARLLDWYRSERLAKLGSGHPRVNDKTVSALEK--NPVQSDSDAVYAKHLV 296

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           +DL++LT Y+SGPNSVK+SN++ DL +QDI INKAYLVSCTNSRLSD+Q+AADV+     
Sbjct: 297 VDLSSLTPYISGPNSVKISNSLADLVEQDIPINKAYLVSCTNSRLSDIQAAADVI----- 351

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
             + +KVAPGVEFYVAAASS ++ DA  +GAW+ +L+AG  PLP+GCGPCIGLG GLL+ 
Sbjct: 352 --RGHKVAPGVEFYVAAASSNVQKDAEAAGAWKTILEAGAKPLPAGCGPCIGLGTGLLKD 409

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASP VVAASAVLG+I  P E+   S +    +   
Sbjct: 410 GEVGISATNRNFKGRMGSKDALAYLASPEVVAASAVLGRIGGPQELEGKSVLSTREIIKT 469

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
           I E  V E+           +VE+LEGFP+   GEL+LCDADNINTDGIYPGKYTYQDD+
Sbjct: 470 IEETKVSEDAA------TGGAVEVLEGFPKVIEGELILCDADNINTDGIYPGKYTYQDDI 523

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
           P+EKMA+VCMENYDAEF  K   GDI++SG+NFGTGSSREQAATA+LA+G+ LVV+GSFG
Sbjct: 524 PREKMAEVCMENYDAEFNGKTKAGDIIISGYNFGTGSSREQAATAILARGMKLVVAGSFG 583

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIP LI  LR KY G+  ELT RTGW LKWDV  A V V +   +
Sbjct: 584 NIFSRNSINNALLTLEIPDLINNLRAKYAGSD-ELTVRTGWILKWDVTTATVEVKDS--E 640

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           G V+L+QKVGELG NLQ+IIVKGGLEGWV+S+L
Sbjct: 641 GNVVLKQKVGELGTNLQDIIVKGGLEGWVRSEL 673
>ref|XP_445684.1| unnamed protein product [Candida glabrata]
 emb|CAG58595.1| unnamed protein product [Candida glabrata CBS 138]
          Length = 777

 Score =  884 bits (2285), Expect = 0.0,   Method: Composition-based stats.
 Identities = 164/759 (21%), Positives = 285/759 (37%), Gaps = 95/759 (12%)

Query: 3   RSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWP 62
                       +   +     EKI+  +  +    ++     Y+ ++P      D +  
Sbjct: 41  YKQNIEYVDIVRKRLGRPLTYAEKILYGHLDDPHGQQIERGVSYLKLRPDRVACQDATAQ 100

Query: 63  VA-LKFMGLGATKIKNPSQIVTTLDHDIQN-----KSEK-----NLTKYKNIENFAKKHH 111
           +A L+FM  G  ++  P  +    DH IQ      K  K     N   Y  + + + K++
Sbjct: 101 MAILQFMSAGLPEVARPVTV--HCDHLIQAQIGGEKDLKRAVDLNKEVYDFLASASAKYN 158

Query: 112 IDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQ 171
           I  +  G GI HQI++E  YAFP  + + +DSH+   GGLG L   +   DA  + A   
Sbjct: 159 IGFWKPGSGIIHQIVLEN-YAFPGALIIGTDSHTPNAGGLGQLAIGVGGADAVDVMAGLP 217

Query: 172 TWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRL 231
              + P +  V+L G++    S KDII+ L G+          +E+ G+ ++        
Sbjct: 218 WELKAPKILGVKLTGRMNGWTSPKDIILKLAGITTVKGGTGKIVEYFGEGVDTFSATGMG 277

Query: 232 TIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADK 291
           TI NM  E GA + +FP +K++ID+ K   +          +            +  AD+
Sbjct: 278 TICNMGAEIGATTSVFPFNKSMIDYLKATRRDKIAEFAQLYHK----------DLLSADQ 327

Query: 292 DAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNSRL 345
            A Y + + IDL TL  YV+GP +  ++  +  + +        +++    + SCTNS  
Sbjct: 328 GAEYDEVIEIDLNTLEPYVNGPFTPDLATPISKMKEVAVENNWPLEVKVGLIGSCTNSSY 387

Query: 346 SDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPS 405
            D+  +A ++           +     F V   S +I A   + G  E   + G I L +
Sbjct: 388 EDMSRSASIIKDAASHG----LKAKSIFTVTPGSEQIRATIERDGQLETFKEFGGIVLAN 443

Query: 406 GCGPCIGLGAGL-LEPGEVG--ISATNRNFKGRM-GSKDALAYLASPAVVAASAVLGK-- 459
            CGPCIG      ++ G+    +S+ NRNF  R  G+    A++ASP +V A A+ G   
Sbjct: 444 ACGPCIGQWDRQDIKKGDKNTIVSSYNRNFTSRNDGNPQTHAFVASPEIVTAFAIAGDLR 503

Query: 460 ---ISSPAEVLST-------------SEIPFSGVKTEIIENPVVEEEVNAQTEAPKQSVE 503
              ++   +                  E  +   +      P     V+ +       ++
Sbjct: 504 FNPLTDKLKDKDGNEFKLKEPFGNGLPERGYDPGENTYQAPPKDRNAVDVKVAPTSDRLQ 563

Query: 504 ILEGFPRE-----FSGELVLC-----DADNINTDGIYPGKYTYQDDVPKE-KMAQVCMEN 552
           +L+ F         +  +++        D+I+  G +     + +++     +  +  EN
Sbjct: 564 VLKPFKPWDGKDALNMPILIKSLGKTTTDHISMAGPWLKYRGHLENISNNYMIGAINAEN 623

Query: 553 YDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGINLV 594
             A     V+ G                   +V+   NFG GSSRE AA      G   +
Sbjct: 624 KKANSVRNVYTGEYKGVPDTARDYRDEGIKWVVIGDENFGEGSSREHAALEPRFLGGFAI 683

Query: 595 VSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADAKV 652
           ++ SF  I   N     LL L    PA   K+    +     LT               V
Sbjct: 684 ITKSFARIHETNLKKQGLLPLNFKNPADYDKINPDDKIDILGLTELA--------PGKNV 735

Query: 653 VVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
            +     +G     +          E    G     +K+
Sbjct: 736 TMRVHPKNGEAWDCELTHTFNSEQIEWFKYGSALNKIKA 774
>ref|XP_502616.1| hypothetical protein [Yarrowia lipolytica]
 emb|CAG80804.1| unnamed protein product [Yarrowia lipolytica CLIB122]
          Length = 769

 Score =  884 bits (2285), Expect = 0.0,   Method: Composition-based stats.
 Identities = 166/742 (22%), Positives = 270/742 (36%), Gaps = 96/742 (12%)

Query: 16  AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVA-LKFMGLGATK 74
              +     EKI+  +     E ++V    Y+ ++P      D +  +A L+FM  G   
Sbjct: 47  RLNRPLTYAEKILYGHLDKPHEQEIVRGQSYLKLRPDRAACQDATAQMAILQFMSAGIPT 106

Query: 75  IKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQ 124
           ++ P+ +    DH IQ             + N   Y  +   + K+ I  + AG GI HQ
Sbjct: 107 VQTPTTV--HCDHLIQAQVGGEQDLARAIDINKEVYNFLGTASAKYDIGFWKAGSGIIHQ 164

Query: 125 IMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVEL 184
           I++E  YAFP  + + SDSH+   GGLG L   +   D   + A      + P +  V+L
Sbjct: 165 IILEN-YAFPGALLIGSDSHTPNAGGLGMLAIGVGGADVVDVMAGLPWELKAPKIIGVKL 223

Query: 185 KGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALS 244
            G+L    S KDII+ + G+          +E+ GD ++ L      TI NM  E GA +
Sbjct: 224 TGKLSGWTSPKDIILKVAGILTVKGGTGAIVEYFGDGVDNLSCTGMGTICNMGAEIGATT 283

Query: 245 GLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLA 304
             FP ++ + D+     +K                         AD+   Y + + IDL 
Sbjct: 284 STFPFNERMADYLNATGRKEIA-----------DFARLYNHFLSADEGCEYDQLIEIDLN 332

Query: 305 TLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNSRLSDLQSAADVVCPT 358
           TL  YV+GP +  ++  +  L          +++    + SCTNS   D++ +A +    
Sbjct: 333 TLEPYVNGPFTPDLATPISKLKDVAVENGWPLEVKVGLIGSCTNSSYEDMERSASIAKDA 392

Query: 359 GDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLG-AGL 417
                   +     + V   S +I A   + G  +  L  G I L + CGPCIG      
Sbjct: 393 MAHG----LKSKSIYTVTPGSEQIRATIERDGQLQTFLDFGGIVLANACGPCIGQWDRRD 448

Query: 418 LEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGKI-----------SSP 463
           ++ GE    +S+ NRNF GR   +    A++ SP +V A A+ G +           S  
Sbjct: 449 IKKGEKNTIVSSYNRNFTGRNDSNPATHAFVTSPDLVTAFAIAGDLRFNPLTDSLKDSEG 508

Query: 464 AEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQSVEILEGFPRE----- 511
            E      +   +P   +          P     V          ++IL+ F        
Sbjct: 509 KEFKLKEPTGKGLPDRGYDPGMDTYQAPPADRSAVEVDVSPTSDRLQILKPFKPWDGKDG 568

Query: 512 FSGELVLC-----DADNINTDGIYPGKYTYQDDVPKE-KMAQVCMENYDAEFRTKVHPG- 564
               +++        D+I+  G +     +  ++     +  +  EN +A        G 
Sbjct: 569 IDMPILIKSLGKTTTDHISQAGPWLKYRGHLQNISNNYMIGAINAENEEANNVRNQITGE 628

Query: 565 -----------------DIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNS 607
                             +VV G NFG GSSRE AA      G   +++ SF  I   N 
Sbjct: 629 WGGVPETAIAYRDNGIRWVVVGGDNFGEGSSREHAALEPRFLGGFAIITKSFARIHETNL 688

Query: 608 INNALLTLEIP--ALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVIL 665
               LL L     A   K++   + +   L                V +     DG    
Sbjct: 689 KKQGLLPLNFVNGADYDKIQPSDKISILGLKDLA--------PGKNVTIEVTPKDGAKWT 740

Query: 666 EQKVGELGKNLQEIIVKGGLEG 687
            +          E    G    
Sbjct: 741 TEVSHTYNSEQLEWFKYGSALN 762
>ref|XP_001644039.1| hypothetical protein Kpol_1026p29 [Vanderwaltozyma polyspora DSM
           70294]
 gb|EDO16181.1| hypothetical protein Kpol_1026p29 [Vanderwaltozyma polyspora DSM
           70294]
          Length = 780

 Score =  883 bits (2282), Expect = 0.0,   Method: Composition-based stats.
 Identities = 163/760 (21%), Positives = 275/760 (36%), Gaps = 97/760 (12%)

Query: 3   RSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWP 62
                           +     EKI+  +       ++V    Y+ ++P      D +  
Sbjct: 42  YKQNLENVNTVRDRLNRPLTYAEKILYGHLDEPHTQEIVRGTSYLKLRPDRVACQDATAQ 101

Query: 63  VA-LKFMGLGATKIKNPSQIVTTLDHDIQN-----KSEK-----NLTKYKNIENFAKKHH 111
           +A L+FM  G  ++  P  +    DH IQ      K  +     N   Y  + +   K++
Sbjct: 102 MAILQFMSAGIPEVARPVTV--HCDHLIQAQVGGEKDLERAISLNKEVYDFLSSATAKYN 159

Query: 112 IDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQ 171
           +  +  G GI HQI++E  YA+P  + + +DSH+   GGLG L   +   DA  + +   
Sbjct: 160 MGFWKPGSGIIHQIVLEN-YAYPGALIIGTDSHTPNAGGLGQLAIGVGGADAVDVMSNLP 218

Query: 172 TWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRL 231
              + P +  V+L G++    S KDII+ L G+          +E+ GD ++        
Sbjct: 219 WELKAPKILGVKLTGKMNGWTSPKDIILKLAGITTVKGGTGKIVEYFGDGIDTFSATGMG 278

Query: 232 TIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADK 291
           TI NM  E GA + +FP +K++I++     +                       +  AD+
Sbjct: 279 TICNMGAEIGATTSVFPFNKSMIEYLDATGRNQIAQFAELYKS----------DLLSADE 328

Query: 292 DAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINK------AYLVSCTNSRL 345
            A Y + + IDL TL  YV+GP +  ++  +  +    +K N         + SCTNS  
Sbjct: 329 GAEYDEVIEIDLNTLEPYVNGPFTPDLATPISKMKDVAVKNNWPLEVKVGLIGSCTNSSY 388

Query: 346 SDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPS 405
            D+  AA +V           +     + V   S +I A   + G  +     G + L +
Sbjct: 389 EDMSRAASIVKDAEAHG----LKAKSIYTVTPGSEQIRATIERDGQLKTFQDFGGVVLAN 444

Query: 406 GCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRM-GSKDALAYLASPAVVAASAVLGKI- 460
            CGPCIG      ++ G+    +S+ NRNF  R  G+ +  +++ASP +V A A+ G + 
Sbjct: 445 ACGPCIGQWDRKDIKKGDKNTIVSSFNRNFTSRNDGNPETHSFVASPDIVTAFAIAGDLR 504

Query: 461 ----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQSVE 503
                         E      +   +P   +          P     V  Q       ++
Sbjct: 505 FNPLTDKLKDKDGNEFMLKPPTGEGLPSRGYDPGNNTYQAPPTDRASVQVQISPSSDRLQ 564

Query: 504 ILEGFPRE-----FSGELVLC-----DADNINTDGIYPGKYTYQDDVPKE-KMAQVCMEN 552
           +L+ F            +++        D+I+  G +     +  ++     +  +  EN
Sbjct: 565 VLKPFEAWNGKDALDMPILIKAVGKTTTDHISMAGPWLKYRGHLQNISNNYMIGAINAEN 624

Query: 553 YDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGINLV 594
             A        G                   +V+   NFG GSSRE AA      G   +
Sbjct: 625 KKANSVKNCLTGEFGGVPDTAGYLRDHGVKWVVIGDENFGEGSSREHAALEPRFLGGFAI 684

Query: 595 VSGSFGNIFSRNSINNALLTLEIP--ALIKKLREKYQGAPKELTR-RTGWFLKWDVADAK 651
           ++ SF  I   N     LL L     A   K+    +     LT    G  L   V    
Sbjct: 685 ITKSFARIHETNLKKQGLLPLNFKNTADYDKINPDDRIDILGLTEFAPGKTLTMRV---- 740

Query: 652 VVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
                   +G     +      K   E    G     +K 
Sbjct: 741 -----HPKNGEAWDCELTHTFNKEQIEWFKSGSALNKIKH 775
>ref|XP_001878558.1| aconitate hydratase [Laccaria bicolor S238N-H82]
 gb|EDR11257.1| aconitate hydratase [Laccaria bicolor S238N-H82]
          Length = 766

 Score =  882 bits (2280), Expect = 0.0,   Method: Composition-based stats.
 Identities = 159/759 (20%), Positives = 281/759 (37%), Gaps = 99/759 (13%)

Query: 2   LRSTTFTRSFHSSR-AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +       +    R    +   L+EKI+  +  +     +     Y+ ++P      D +
Sbjct: 24  INYQRIEDNLAIVRDRLNRPLTLSEKILYGHLDDPHGQDIERGTSYLKLRPDRVACQDAT 83

Query: 61  WPVAL-KFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +AL +FM  G      P+ +    DH I+               N   Y  +     K
Sbjct: 84  AQMALLQFMSAGMDTAAVPTTV--HCDHLIEAQIGGVKDLARAISINKEVYDFLATATAK 141

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           + +  +  G GI HQI++E  YAFP  + + +DSH+   GGLG +   +   DA  + A 
Sbjct: 142 YGLGFWKPGSGIIHQIILEN-YAFPGGLMIGTDSHTPNAGGLGMIACGVGGADAVDVMAG 200

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V L G++    + KD+I+ + G+          +E+ G  + +L    
Sbjct: 201 IPWELKCPKVIGVNLTGKISGWTTPKDVILKVAGILTVKGGTGAIVEYKGPGVESLSCTG 260

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + +FP +  ++D+     +    N             ++ A   KA
Sbjct: 261 MATICNMGAEIGATTSMFPFNHRMVDYLNATKRGDIAN-----------YAKQFAHNLKA 309

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIK------INKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +   +++  K      I    + SCTNS
Sbjct: 310 DEGAEYDQVIEINLSELEPHINGPFTPDLATPISKFAEEAKKNNWPEEIKVGLIGSCTNS 369

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  +A +V    D      +    +F +   S ++ A   + G  E     G + L
Sbjct: 370 SYEDMSRSASIVKQAADHG----IHLKSKFTITPGSEQVRATIARDGQIEAFESVGGLVL 425

Query: 404 PSGCGPCIGLGAGL-LEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    I++ NRNF GR   +    A++ASP +V A +  G+
Sbjct: 426 ANACGPCIGQWDRQDVKKGEPNTIITSYNRNFTGRNDANPATHAFVASPDIVTAMSFAGR 485

Query: 460 -----ISS--------PAEV--LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
                ++         P +    +  E+P   +   +      P     VN   +     
Sbjct: 486 VSFNPLTDSLIGSDGKPFKFSDPAGHELPPRGYDPGEDTFQPPPADRASVNVAVDPKSDR 545

Query: 502 VEILEGFPREF-----SGELVL-----CDADNINTDGIYPGKYTYQDDVPKE-KMAQVCM 550
           +++LE F            +++     C  D+I+  G +     +  ++ +   +  +  
Sbjct: 546 LQLLEPFLPWDGKTPTDLPILIKVSGKCTTDHISAGGPWLKYRGHLQNISQNCLIGAINA 605

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN +A        G                   +V+   N+G GSSRE AA      G  
Sbjct: 606 ENNEANKVKNQFTGEYGGVPQVGAAYRDNGVKWVVIGDHNYGEGSSREHAALEPRYLGGL 665

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTR-RTGWFLKWDVAD 649
            ++  SF  I   N     +L L    PA   K+R   +     L     G  L      
Sbjct: 666 AIIVRSFARIHETNLKKQGMLALTFVDPADYDKIRPSDRVDILGLESFAPGKNL------ 719

Query: 650 AKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGW 688
               +     DG            +        G     
Sbjct: 720 ---TLVAKHEDGSKTEIPLAHSFNEGQIAWFKAGSALNL 755
>sp|Q2HZ33|LYS4_CANPA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 gb|ABC94604.1| homoaconitase [Candida parapsilosis]
          Length = 688

 Score =  882 bits (2280), Expect = 0.0,   Method: Composition-based stats.
 Identities = 484/693 (69%), Positives = 553/693 (79%), Gaps = 19/693 (2%)

Query: 7   FTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALK 66
             R   +S     GQNLTEKIVQ YAVNLP  K+VH+GDYV+IKPAHCMSHDNSWPVA K
Sbjct: 5   LHRFISTSTPLRSGQNLTEKIVQKYAVNLPPNKLVHTGDYVTIKPAHCMSHDNSWPVATK 64

Query: 67  FMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIM 126
           FMGLGA ++K+  QIV TLDHD+QNK+EKNL KY NIE FAK+  ID YPAGRGIGHQIM
Sbjct: 65  FMGLGAKRVKDNRQIVCTLDHDVQNKTEKNLAKYANIERFAKEQGIDFYPAGRGIGHQIM 124

Query: 127 IEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKG 186
           IEEGYAFPLN+TVASDSHSNTYGG+GSLGTPIVRTDAA+IWAT QTWWQIPPVA+VELKG
Sbjct: 125 IEEGYAFPLNLTVASDSHSNTYGGVGSLGTPIVRTDAASIWATVQTWWQIPPVAKVELKG 184

Query: 187 QLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGL 246
            L  GV+GKDIIVALCG+FNND+VLNHAIEF GD +  LPID+RLTIANMTTEWGALSGL
Sbjct: 185 NLQNGVTGKDIIVALCGVFNNDEVLNHAIEFVGDGVENLPIDYRLTIANMTTEWGALSGL 244

Query: 247 FPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATL 306
           FP+D  LI++Y+ RLQKLG N HPRIN  TI AL        +D+DA YAK L+IDL TL
Sbjct: 245 FPIDDKLIEFYEGRLQKLGPN-HPRINKDTIEALRR--GSLASDEDAKYAKHLVIDLNTL 301

Query: 307 THYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNK 366
           + YVSGPNSVKVSN +  LSQ +I INKAYLVSCTNSRLSD+Q+AADV+       K +K
Sbjct: 302 SPYVSGPNSVKVSNPLSKLSQDNIAINKAYLVSCTNSRLSDIQAAADVL-------KGHK 354

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           V P VEFYVAAASS ++ DA  +GAW+ ++ AG  PLP+GCGPCIGLG GLL+ GEVGIS
Sbjct: 355 VHPNVEFYVAAASSLVQQDAEAAGAWQTIIDAGAKPLPAGCGPCIGLGTGLLKDGEVGIS 414

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPV 486
           ATNRNFKGRMGSKDALAYLASP VVAASAVLGKI +P E+          +   I     
Sbjct: 415 ATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGAPEEIDGKPVNASPEIVKSIDLPKS 474

Query: 487 VE------EEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
                   EE  ++ +  + SVE+L GFP+   GEL+LC+ADNINTDGIYPGKYTYQDD+
Sbjct: 475 SGNTGATSEEPISEDDTSEASVEVLPGFPKSIQGELILCNADNINTDGIYPGKYTYQDDI 534

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
            +E+MA+VCMENYD EF+TK    DI++SG+NFGTGSSREQAAT +LA+G+ LVV+GSFG
Sbjct: 535 SREQMAEVCMENYDPEFKTKTKSDDIIISGYNFGTGSSREQAATCILARGMKLVVAGSFG 594

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINNALLTLEIP LI+KLR KY G   ELT RTGWFLKWDV  A V V +  LD
Sbjct: 595 NIFSRNSINNALLTLEIPELIEKLRVKYDG-VNELTIRTGWFLKWDVTKALVTVAD--LD 651

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           G VIL+QKVGELG NLQ+IIVKGGLEGWVKS+L
Sbjct: 652 GEVILQQKVGELGTNLQDIIVKGGLEGWVKSEL 684
>ref|XP_716225.1| mitochondrial aconitate hydratase [Candida albicans SC5314]
 ref|XP_716141.1| mitochondrial aconitate hydratase [Candida albicans SC5314]
 gb|EAK97138.1| likely mitochondrial aconitate hydratase [Candida albicans SC5314]
 gb|EAK97226.1| likely mitochondrial aconitate hydratase [Candida albicans SC5314]
          Length = 777

 Score =  881 bits (2279), Expect = 0.0,   Method: Composition-based stats.
 Identities = 155/760 (20%), Positives = 275/760 (36%), Gaps = 95/760 (12%)

Query: 3   RSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWP 62
                           +     EK++  +  +    ++     Y+ ++P      D +  
Sbjct: 42  YKKHLENVEIVKSRLNRPLTYAEKLLYGHLDDPHNQEIERGVSYLKLRPDRVACQDATAQ 101

Query: 63  VA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKKHH 111
           +A L+FM  G  ++  PS +    DH IQ             + N   Y  +     K++
Sbjct: 102 MAILQFMSAGIPQVATPSTV--HCDHLIQAQVGGPKDLARAIDLNKEVYDFLSTACAKYN 159

Query: 112 IDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQ 171
           +  +  G GI HQI++E  YAFP  + + +DSH+   GGLG L   +   DA  + +   
Sbjct: 160 LGFWKPGSGIIHQIVLEN-YAFPGALLIGTDSHTPNAGGLGQLAIGVGGADAVDVMSGLP 218

Query: 172 TWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRL 231
              + P +  V+L G++    S KDII+ L G+          +E+ G  ++        
Sbjct: 219 WELKAPKIIGVKLTGKMSGWTSPKDIILKLAGITTVKGGTGSIVEYFGSGVDTFSCTGMG 278

Query: 232 TIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADK 291
           TI NM  E GA + +FP + +++D+     +                A   K     AD+
Sbjct: 279 TICNMGAEIGATTSVFPFNDSMVDYLNATGRSEIAQF----------AQVYKKDFLSADE 328

Query: 292 DAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDI------KINKAYLVSCTNSRL 345
            A Y + + IDL TL  +++GP +  ++  V  + +  I      ++    + SCTNS  
Sbjct: 329 GAEYDQVIEIDLNTLEPHINGPFTPDLATPVSKMKETAIANGWPLEVKVGLIGSCTNSSY 388

Query: 346 SDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPS 405
            D+  AA ++   G       +     + V+  S ++ A   + G  +     G + + +
Sbjct: 389 EDMTRAASIIKDAGAHG----LKSKALYTVSPGSEQVRATIARDGQLKTFEDFGGVVMAN 444

Query: 406 GCGPCIGLGAGL-LEPGEVG--ISATNRNFKGRM-GSKDALAYLASPAVVAASAVLGKI- 460
            CGPCIG      ++ G+    +S+ NRNF  R  G+    A++ASP +    A+ G + 
Sbjct: 445 ACGPCIGQWDRQDIKKGDKNTIVSSFNRNFTARNDGNPATHAFVASPEMATVYAISGDLG 504

Query: 461 ----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQSVE 503
                     +   E          +P   +   +      P     V          ++
Sbjct: 505 FNPITDTLVGADGKEFKLKEPQGVGLPPDGYDPGENTYQAPPEDRASVEVVISPTSDRLQ 564

Query: 504 ILEGFPREFSG-----ELVLC-----DADNINTDGIYPGKYTYQDDVPKE-KMAQVCMEN 552
            L  F            +++        D+I+  G +     + +++     +  +  EN
Sbjct: 565 KLSPFKPWDGKDAERLPILIKAVGKTTTDHISMAGPWLKYRGHLENISNNYMIGAINAEN 624

Query: 553 YDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGINLV 594
             A      + G                   +V+   NFG GSSRE AA      G   +
Sbjct: 625 GKANEVRNHYTGKYDGVPQTAAAYRDAGHKWVVIGDENFGEGSSREHAALEPRFLGGFAI 684

Query: 595 VSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADAKV 652
           ++ SF  I   N     LL L    PA   K+    +     LT               V
Sbjct: 685 ITKSFARIHETNLKKQGLLPLNFKNPADYDKINFDDEVDLIGLTTLA--------PGKDV 736

Query: 653 VVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
           ++     +G                E    G    ++KS+
Sbjct: 737 ILRVHPKEGEAWEAVLTHTFNSEQLEWFKHGSALNFIKSK 776
>ref|ZP_03966826.1| aconitate hydratase [Sphingobacterium spiritivorum ATCC 33300]
 gb|EEI93348.1| aconitate hydratase [Sphingobacterium spiritivorum ATCC 33300]
          Length = 755

 Score =  881 bits (2278), Expect = 0.0,   Method: Composition-based stats.
 Identities = 161/761 (21%), Positives = 277/761 (36%), Gaps = 91/761 (11%)

Query: 2   LRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNL-PEGKVVHSGDYVSIKPAHCMSHDNS 60
           + S    R   + +   K   L+EKI+ ++  +            YV   P      D +
Sbjct: 11  VYSQYDERITAARKVVNKPLTLSEKILYAHLWDGNASQAYERGNSYVDFAPDRVAMQDAT 70

Query: 61  WPVAL-KFMGLGATKIKNPSQIVTTLDHDIQNKS----------EKNLTKYKNIENFAKK 109
             +AL +FM  G  K+  PS +    DH IQ K           +++   +  + + + K
Sbjct: 71  AQMALLQFMQAGRPKVAVPSTV--HCDHLIQAKEGAEKDLTRAKQESSEVFNFLSSVSNK 128

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           + I  +  G GI HQ+++E  YAFP  M + +DSH+   GGLG +   +   DA  + A 
Sbjct: 129 YGIGFWKPGAGIIHQVVLEN-YAFPGGMMIGTDSHTVNAGGLGMIAIGVGGADACDVMAG 187

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P +  V+L G+L    S KD+I+ + G+          +E+ G+   ++    
Sbjct: 188 LPWELKFPKLIGVKLTGKLSGWTSPKDVILKVAGILTVKGGTGAIVEYFGEGATSMSCTG 247

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
           + TI NM  E GA +  F  D+++  + +   +    +    I        E       A
Sbjct: 248 KGTICNMGAEIGATTSTFGYDESMERYLRATDRAEVADAANTIKEHLTADAE-----VYA 302

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQ------DIKINKAYLVSCTNS 343
           D + ++ + + I+L+ L   ++GP +  +   +  + ++       + +    + SCTNS
Sbjct: 303 DPETYFDQVIEINLSELEPSLNGPFTPDLYTPISRMREEAQKNGWPLTVEWGLIGSCTNS 362

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              DL  AA +     D   V K     EF +   S ++   A + G  +   +      
Sbjct: 363 SYEDLSRAASIAKQAVDKGLVTK----AEFGINPGSEQVRFTADRDGLLQTFEELNATIF 418

Query: 404 PSGCGPCIGLGAGLLEPG-EVG--ISATNRNFKGRM-GSKDALAYLASPAVVAASAVLGK 459
            + CGPCIG+   +     E    + + NRNF  R  G+ +  A++ SP +VAA A+ G 
Sbjct: 419 TNACGPCIGMWDRVGADKQEKNTIVHSFNRNFAKRADGNPNTFAFVTSPEMVAAIAISGD 478

Query: 460 -----ISS----------PAEVLSTSEIPFSGV---KTEIIENPVVEEEVNAQTEAPKQS 501
                ++             +     E+P  G                 V          
Sbjct: 479 LGFNPLTDTLTNSKGEQVKLDPPVGDELPTKGFAVDDPGYQAPAADGSSVVVAVSPESDR 538

Query: 502 VEILEGFPRE----FSGELVL------CDADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           +++LE F         G  +L      C  D+I+  G +     + D++    +   V  
Sbjct: 539 LQLLEPFAAWEGTDLKGLKLLIKAKGKCTTDHISMAGPWLKYRGHLDNISNNMLIGAVNY 598

Query: 551 ENYDAEFRTKVHP------------------GDIVVSGFNFGTGSSREQAATALLAKGIN 592
            N   +                         G IVV   N+G GSSRE AA      G+ 
Sbjct: 599 FNEKTDSVKNQLTGAYGPVPATQRDYKAAGIGSIVVGDENYGEGSSREHAAMEPRHLGVR 658

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            V+  SF  I   N     +L L         K+RE        LT            + 
Sbjct: 659 AVLVKSFARIHETNLKKQGMLGLTFANKEDYDKIRENDTIDIIGLTTFA--------PNT 710

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
            + +     DG            +        GG    ++ 
Sbjct: 711 PLTLVLHHEDGTQEEILANHTYNEQQIGWFKAGGALNIIRQ 751
>ref|XP_001587807.1| hypothetical protein SS1G_11047 [Sclerotinia sclerotiorum 1980]
 gb|EDN95172.1| hypothetical protein SS1G_11047 [Sclerotinia sclerotiorum 1980]
          Length = 783

 Score =  880 bits (2276), Expect = 0.0,   Method: Composition-based stats.
 Identities = 158/757 (20%), Positives = 272/757 (35%), Gaps = 98/757 (12%)

Query: 2   LRSTTFTRSFHSSR-AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +     + +    R    +     EKI+ S+  +    ++     Y+ ++P      D +
Sbjct: 47  INYKKMSENLSIVRQRLNRPLAYAEKILYSHLDDPHGQEIERGVSYLKLRPDRVACQDAT 106

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G   + NP+ +    DH I+             + N   Y  +     K
Sbjct: 107 AQMAILQFMSAGMPSVANPTTV--HCDHLIEAQAGGAKDLTRAIDINKEVYDFLSTSCAK 164

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  YAFP  + + +DSH+   GGLG     +   DA  + A 
Sbjct: 165 YNIGFWKPGSGIIHQIILEN-YAFPGGLLIGTDSHTPNAGGLGMAAIGVGGADAVDVMAN 223

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  ++L G+L    + KDII+ + G+          +E+ G   N++    
Sbjct: 224 LPWELKAPKVIGIKLTGELSGWATPKDIILKVAGILTVKGGTGAIVEYFGPGTNSISCTG 283

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
           + TI NM  E GA + LFP +  + D+     +                     AK  + 
Sbjct: 284 QATICNMGAEIGATTSLFPFNDRMYDYLAATKRTEIG-----------DFARTYAKELRE 332

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +   S+         ++    + SCTNS
Sbjct: 333 DEGAQYDELIEINLSELEPHINGPFTPDLATPISKFSEAVKANNWPEELKVGLIGSCTNS 392

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     D      V     F V   S +I A   + G  E   + G + L
Sbjct: 393 SYEDMTRAASIARDAMDHG----VKAKSLFTVTPGSEQIRATIERDGQLETFEQFGGMVL 448

Query: 404 PSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    IS+ NRNF GR   +    +++ASP +V A  + G 
Sbjct: 449 ANACGPCIGQWDRKDVKKGEANSIISSYNRNFTGRNDANPATHSFVASPDMVVAMTIAGS 508

Query: 460 I-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           +               E      +   +P   +   +      P     VN         
Sbjct: 509 LHFNPLTDTLKDKDGKEFKLSPPTGDGLPSRGYDPGQDTYQAPPAERASVNVAVSPTSDR 568

Query: 502 VEILEGFPRE-----FSGELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           +++LE F            +++        D+I+  G +     + D++    +      
Sbjct: 569 LQLLEPFKPWDGKDALDMPILIKAKGKTTTDHISMAGPWLKYRGHLDNISNNMLIGATNS 628

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
            N +A        G                   +VV  +N+G GSSRE AA      G  
Sbjct: 629 ANGEANKVKNFTTGEFDAVPATARDYKKKGIPWVVVGDWNYGEGSSREHAALEPRHLGGL 688

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    P    K+    +          G  +       
Sbjct: 689 AIITKSFARIHETNLKKQGMLPLTFINPEDYDKIDPYDKVDLMCTELAVGKPM------- 741

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEG 687
              +      G     +          E    G    
Sbjct: 742 --TLKVHPKSGETFEIKLAHTFNAPQIEWFKNGSALN 776
>ref|XP_001219634.1| hypothetical protein CHGG_00413 [Chaetomium globosum CBS 148.51]
 gb|EAQ92178.1| hypothetical protein CHGG_00413 [Chaetomium globosum CBS 148.51]
          Length = 787

 Score =  879 bits (2273), Expect = 0.0,   Method: Composition-based stats.
 Identities = 162/758 (21%), Positives = 290/758 (38%), Gaps = 99/758 (13%)

Query: 2   LRSTTFTRSFHSSRAWL--KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDN 59
           +     + +    R+ L  +     EKI+ S+  +     +     Y+ ++P      D 
Sbjct: 49  INYKKMSENLSIVRSRLNNRPLTFAEKILYSHLDDPHNQDIERGVSYLKLRPDRVACQDA 108

Query: 60  SWPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN-----KSEK-----NLTKYKNIENFAK 108
           +  +A L+F+  G  ++ NP+ +    DH I+      K  +     N   Y  + +   
Sbjct: 109 TAQMAILQFISAGLPQVANPTTV--HCDHLIEAQIGGAKDLERAVGINKEVYDFLASACA 166

Query: 109 KHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWA 168
           K++I  +  G GI HQI++E  YAFP  + + +DSH+   GGLG     +   DA  + A
Sbjct: 167 KYNIGFWKPGSGIIHQILLEN-YAFPGGLLIGTDSHTVNGGGLGMAAIGVGGADAVDVMA 225

Query: 169 TGQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPID 228
                 + P V  V+L GQ+    + KDII+ + G+          +E+ G  ++++   
Sbjct: 226 NLPWELKAPKVIGVKLTGQMSGWTAPKDIILKVAGILTVKGGTGAIVEYHGPGVDSISAT 285

Query: 229 HRLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPK 288
              T+ANM  E GA + +FP +  + D+     +K                    AK  +
Sbjct: 286 GMATVANMGAEIGATTSVFPFNDRMYDYLVATKRKEIG-----------DFARSYAKELR 334

Query: 289 ADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTN 342
            D+ A Y + + I+L+ L  +++GP +  ++  +   ++         ++    + SCTN
Sbjct: 335 EDEGAEYDQLIEINLSELEPHINGPFTPDLATPISKFTEAVKTNGWPEELKVGLIGSCTN 394

Query: 343 SRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIP 402
           S   D+  AA +     +     K     EF+V   S +I A   + G      + G + 
Sbjct: 395 SSYEDMSRAAAIARDALNHGLKTK----SEFFVTPGSEQIRATIARDGQLHTFEEFGGVV 450

Query: 403 LPSGCGPCIGLG-AGLLEPGEVG--ISATNRNFKGRM-GSKDALAYLASPAVVAASAVLG 458
           L + CGPCIG      ++ GE    IS+ NRNF GR  G+    +++ SP +V A ++ G
Sbjct: 451 LANACGPCIGQWDRRDVKKGEANSIISSYNRNFTGRNDGNPATHSFVTSPDLVVAMSIAG 510

Query: 459 KIS-----------SPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQ 500
            +S              E      +   +P   +   +      P     V+ Q      
Sbjct: 511 TLSFNPLTDKLKDKDGKEFMLAAPTGESLPANGYDPGQDTYQAPPKDRNAVSVQVSPSSD 570

Query: 501 SVEILEGFPREF-----SGELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVC 549
            ++IL  F           ++++        D+I+  G +     + D++    +   + 
Sbjct: 571 RLQILSPFSAWDGKDATDCQILIKAQGKTTTDHISMAGPWLKYRGHLDNISNNLLIGAIN 630

Query: 550 MENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGI 591
             N +A        G                   +VV  +N+G GSSRE AA      G 
Sbjct: 631 AANGEANKVKNQTTGAFDAVPAVARDYKAKGIKWVVVGDWNYGEGSSREHAALEPRHLGG 690

Query: 592 NLVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVAD 649
             +++ SF  I   N     +L L    PA   K++   +          G  +   V  
Sbjct: 691 LAIITRSFARIHETNLKKQGMLPLTFSDPADYDKIQPDDKVDILCTELAVGKPITMRVHP 750

Query: 650 AKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEG 687
           +       + D  +      G+L     E    G    
Sbjct: 751 S----NGSAFDIKLSHTFNEGQL-----EWFKNGSALN 779
>ref|XP_570245.1| aconitase [Cryptococcus neoformans var. neoformans JEC21]
 ref|XP_775965.1| hypothetical protein CNBD3720 [Cryptococcus neoformans var.
           neoformans B-3501A]
 gb|EAL21318.1| hypothetical protein CNBD3720 [Cryptococcus neoformans var.
           neoformans B-3501A]
 gb|AAW42938.1| aconitase, putative [Cryptococcus neoformans var. neoformans JEC21]
          Length = 792

 Score =  878 bits (2271), Expect = 0.0,   Method: Composition-based stats.
 Identities = 159/761 (20%), Positives = 278/761 (36%), Gaps = 97/761 (12%)

Query: 2   LRSTTFTRSFHSSR-AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +       +    R    +   L EK+V  +  N  E  +     Y+ ++P      D +
Sbjct: 48  INYQRIENNLQVVRSRLNRPLTLAEKVVYGHLDNPHEQDIERGVSYLKLRPDRVACQDAT 107

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G  +   P+ +    DH IQ             + N   Y  +     K
Sbjct: 108 AQMAILQFMSAGLPQTAVPTSV--HCDHLIQAQIGGKADLARAIDINKEVYDFLATACAK 165

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           + I  +  G GI HQI++E  YA P  M + +DSH+   GGLG +   +   DA  + A 
Sbjct: 166 YGIGFWKPGSGIIHQIILEN-YAVPGLMMIGTDSHTPNAGGLGMVACGVGGADAVDVMAD 224

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V L GQ+    + KD+I+ + G+          IE+ G  + +L    
Sbjct: 225 IPWELKAPKVIGVYLDGQMSGWTTPKDVILKVAGILTVKGGTGAIIEYHGPGVESLSCTG 284

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + LFP +  +  + K   +               +  EE     + 
Sbjct: 285 MATICNMGAEIGATTSLFPFNHRMGSYLKATNRSAIA-----------QYAEEFNHNLQP 333

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQ------DIKINKAYLVSCTNS 343
           D+   Y +++ I+L+ L  +++GP +  ++  +   +++        ++    + SCTNS
Sbjct: 334 DEGCEYDQRIEINLSELEPHINGPFTPDLATPLSKFAEEVKRHSWPQELKVGLIGSCTNS 393

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  +A +           K     +F +   S ++ A   + G  +   K G + L
Sbjct: 394 SYEDMSRSAHIAREAASHGLTAK----SQFTITPGSEQVRATIARDGMVDDFEKVGGLVL 449

Query: 404 PSGCGPCIGLG-AGLLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ GE    I++ NRNF GR   +    A++ASP +V A    G 
Sbjct: 450 ANACGPCIGQWDRRDVKKGEANSIITSYNRNFTGRNDANPATHAFVASPDLVTAMIFAGD 509

Query: 460 IS-----------SPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           ++              E      S  E+P   +   +      P     V+         
Sbjct: 510 LTFNPMTDSLKGADGKEFRFSDPSGFELPAKGYDPGENTFQAPPADGTTVSVAVSPTSDR 569

Query: 502 VEILEGFPRE-----FSGELVL-----CDADNINTDGIYPGKYTYQDDVPKE-KMAQVCM 550
           +++L+ F            +++     C  D+I+  G +     + +++ +   +  +  
Sbjct: 570 LQLLKPFKPWDGKDIIEARVLIKAKGKCTTDHISAGGPWLKYRGHLENISQNCLIGAINS 629

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           +N +A        G                   +VV   N+G GSSRE AA      G  
Sbjct: 630 DNGEANKILNQETGEFGPVPTVAAYYRDRDIPWVVVGDENYGEGSSREHAALEPRFLGGR 689

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            V+  SF  I   N     +L L    PA   K+    + +  +L               
Sbjct: 690 AVICRSFARIHETNLKKQGMLPLWFKNPADYDKISGTDKISILDLQNFK--------PGQ 741

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
            + V     DG          + +        G     + S
Sbjct: 742 DIKVEITHKDGSKEQILTTSSINEGQWGWFKAGSALNMMAS 782
>ref|YP_678828.1| aconitate hydratase [Cytophaga hutchinsonii ATCC 33406]
 gb|ABG59486.1| aconitase [Cytophaga hutchinsonii ATCC 33406]
          Length = 755

 Score =  878 bits (2270), Expect = 0.0,   Method: Composition-based stats.
 Identities = 169/764 (22%), Positives = 284/764 (37%), Gaps = 97/764 (12%)

Query: 2   LRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSG-DYVSIKPAHCMSHDNS 60
           + S    R   + +   K   LTEKI+ S+       KV   G  YV   P      D +
Sbjct: 11  VYSLMPQRIEAAKKLIGKPLTLTEKILYSHLDEGTATKVYERGVSYVDFNPDRVAMQDAT 70

Query: 61  WPVAL-KFMGLGATKIKNPSQIVTTLDHDIQNK----------SEKNLTKYKNIENFAKK 109
             +AL +FM  G  K+  PS +    DH I  K          ++++   +  + + + K
Sbjct: 71  AQMALLQFMQAGRPKVAVPSTV--HCDHLITAKEGATKDLPFANKESKEVFDFLGSVSNK 128

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           + I  +  G GI HQ+++E  YAFP  M + +DSH+   GGLG L   +   DA  + A 
Sbjct: 129 YGIGFWKPGAGIIHQVVLEN-YAFPGGMMIGTDSHTVNAGGLGMLAIGVGGADACDVMAG 187

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P +  V+L G+L    + KD+I+ + G+          +E+ G+   ++    
Sbjct: 188 LPWELKFPKLIGVKLTGKLNGWTAPKDVILKVAGILTVKGGTGAIVEYFGEGATSMSCTG 247

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
           + TI NM  E GA +  F  D+++  + +   +    +    I        E       A
Sbjct: 248 KGTICNMGAEIGATTSTFGYDESMERYLRATGRADVADLANGIKQHLNADPE-----VYA 302

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQ------DIKINKAYLVSCTNS 343
             + ++ + + I+L+ L  +++GP +  ++  V  + ++       +K+    + SCTNS
Sbjct: 303 SPEKYFDQVIEINLSELEPHLNGPFTPDLATPVSKMKEEAEKNGWPLKVEWGLIGSCTNS 362

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              DL  AA +         V K     EF +   S ++   A + G             
Sbjct: 363 SYEDLSRAASIAKQAIAKGLVTK----AEFGINPGSEQVRYTADRDGLLGTFTDLNAKIF 418

Query: 404 PSGCGPCIGLGAGL-LEPGEVG--ISATNRNFKGRM-GSKDALAYLASPAVVAASAVLGK 459
            + CGPCIG+   +  E  E    + + NRNF  R  G+ +  A++ASP +VAA A+ G 
Sbjct: 419 TNACGPCIGMWDRVGAEKKEKNTIVHSFNRNFAKRADGNPNTFAFVASPEMVAAIAIAGD 478

Query: 460 IS------------------SPAEVLSTSEIPFSGVKTE---IIENPVVEEEVNAQTEAP 498
           +S                   P       E+P  G   E             V       
Sbjct: 479 LSFNPITDSLINDKGEKVKLDP---PFGDELPTKGFAVEDAGFQAPAADGSAVQVAVSPT 535

Query: 499 KQSVEILEGFPRE----FSGELVL------CDADNINTDGIYPGKYTYQDDVPKEKM-AQ 547
              +++L+ F         G  +L      C  D+I+  G +     + D++    +   
Sbjct: 536 SDRLQLLDPFSAWEGTDLKGLKLLIKAKGKCTTDHISMAGPWLKYRGHLDNISNNMLIGA 595

Query: 548 VCMENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAK 589
           V   N   +       G                   IVV   N+G GSSRE AA      
Sbjct: 596 VNFFNDKTDDVKNQLTGTYGPVPATQRAYKAQGIGSIVVGDENYGEGSSREHAAMEPRHL 655

Query: 590 GINLVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDV 647
           G+  V+  SF  I   N     +L L         K++E        LT           
Sbjct: 656 GVRAVLVKSFARIHETNLKKQGMLGLTFANKDDYNKIQEDDSIDILGLTTFA-------- 707

Query: 648 ADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
            +  + +     DG     +      +   E    GG    +++
Sbjct: 708 PNVPLTLVLNHKDGSKEEIKVNHSYNEQQIEWFKSGGALNIIRA 751
>ref|XP_663129.1| hypothetical protein AN5525.2 [Aspergillus nidulans FGSC A4]
 gb|EAA62685.1| hypothetical protein AN5525.2 [Aspergillus nidulans FGSC A4]
          Length = 766

 Score =  877 bits (2268), Expect = 0.0,   Method: Composition-based stats.
 Identities = 161/762 (21%), Positives = 282/762 (37%), Gaps = 98/762 (12%)

Query: 2   LRSTTFTRSFHSSRAWL-KGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +     + +    R  L +     EKI+ S+  +     +     Y+ ++P      D +
Sbjct: 29  INYKKMSENLDVVRRRLTRPLTYAEKILYSHLDDPQNQDIERGKSYLKLRPDRVACQDAT 88

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN----------KSEKNLTKYKNIENFAKK 109
             +A L+FM  G   +  P+ +    DH I+            +E N   Y  + +   K
Sbjct: 89  AQMAILQFMSAGMPSVATPTTV--HCDHLIEAQLGGEKDLARANEINKEVYDFLASSTAK 146

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           ++I  +  G GI HQI++E  YAFP  + + +DSH+   GGL      +   DA  + A 
Sbjct: 147 YNIGFWKPGSGIIHQIILEN-YAFPGGLMIGTDSHTPNAGGLAIAAIGVGGADAVDVMAG 205

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P V  V L G++    + KDII+ + GL          IE+ G  +N+L    
Sbjct: 206 LPWELKAPKVIGVRLTGEMSGWTAPKDIILKVAGLLTVKGGTGAIIEYHGPGVNSLSATG 265

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
             TI NM  E GA + LFP +  + D+ K   ++                    AK  + 
Sbjct: 266 MATICNMGAEIGATTSLFPFNDRMYDYLKATKRQQIG-----------DFARSYAKDLRE 314

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQ------QDIKINKAYLVSCTNS 343
           D+ A Y + + I+L+ L  +++GP +  ++  +    +         ++    + SCTNS
Sbjct: 315 DEGAEYDQLIEINLSELEPHINGPFTPDLATPISQFKEAVKANGWPEELKVGLIGSCTNS 374

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              D+  AA +     D      +     F V   S +I A   + G  + L + G + L
Sbjct: 375 SYEDMSRAASIAQDALDHG----LKAKSIFTVTPGSEQIRATIERDGQLKTLEEFGGVIL 430

Query: 404 PSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      ++ G     +S+ NRNF GR   +    A++ SP +V A ++ G 
Sbjct: 431 ANACGPCIGQWDRKDVKKGTPNSIVSSYNRNFTGRNDANPATHAFVTSPDLVVALSIAGT 490

Query: 460 IS-----------SPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQS 501
           ++              E      +   +P   +   +      P     V+         
Sbjct: 491 LNFNPLTDTLKDKDGKEFKLKAPTGDGLPSRGYDPGRDTYQAPPTDRSSVDVAVSPSSDR 550

Query: 502 VEILEGFPREFSG-----ELVLC-----DADNINTDGIYPGKYTYQDDVPKEKM-AQVCM 550
           +++L GF            +++        D+I+  G +     + D++    +   V  
Sbjct: 551 LQLLAGFQPWDGKDATGIPILIKCQGKTTTDHISMAGPWLKYRGHLDNISNNMLIGAVNA 610

Query: 551 ENYDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGIN 592
           EN +A     V  G                   +V+  +N+G GSSRE AA      G  
Sbjct: 611 ENGEANKIKNVFTGEYGAVPATARDYKARGVKWVVIGDWNYGEGSSREHAALEPRHLGGL 670

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            +++ SF  I   N     +L L    PA   ++                  L  D    
Sbjct: 671 AIITRSFARIHETNLKKQGMLPLTFSDPADYDRIPPDATVDLLCT------ELAVDKP-- 722

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
            + +     DG     +      ++  E    G     +  +
Sbjct: 723 -MTLRVHPKDGASFDVKLSHTFNESQIEWFKDGSALNTMARK 763
>ref|XP_503471.1| hypothetical protein [Yarrowia lipolytica]
 sp|Q6C791|LYS4_YARLI Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAG79050.1| unnamed protein product [Yarrowia lipolytica CLIB122]
          Length = 687

 Score =  877 bits (2267), Expect = 0.0,   Method: Composition-based stats.
 Identities = 481/694 (69%), Positives = 554/694 (79%), Gaps = 17/694 (2%)

Query: 2   LRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSW 61
           +  T   R + + R     QNLTEKIVQ YAV LPEGK V SGDYVSI+P+HCM+HDNSW
Sbjct: 9   VTQTLLVRRYSTKRI---PQNLTEKIVQRYAVGLPEGKQVQSGDYVSIRPSHCMTHDNSW 65

Query: 62  PVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGI 121
           PVA KF GLGA  +K+  Q+V TLDHD+QNKSEKNL KY NIENFA +  ID YPAGRGI
Sbjct: 66  PVATKFKGLGAKAVKDNRQVVMTLDHDVQNKSEKNLEKYANIENFAGEQGIDFYPAGRGI 125

Query: 122 GHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQ 181
           GHQ+M+EEGYAFP N+TVASDSHSN YGG+G LGTPIVRTDAA++WATGQTWWQIPPVA+
Sbjct: 126 GHQVMVEEGYAFPYNLTVASDSHSNMYGGIGCLGTPIVRTDAASVWATGQTWWQIPPVAR 185

Query: 182 VELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWG 241
           VELKGQLP GV GKD+I+ALCG+FNND+VLNHAIEF GD +  L +D RLTIANMTTEWG
Sbjct: 186 VELKGQLPAGVFGKDVIIALCGIFNNDEVLNHAIEFVGDGVEHLSVDERLTIANMTTEWG 245

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLII 301
           AL+GLFPVD+TL  WY+ RL +     H R+N  T+ AL++     +AD DA YAK L I
Sbjct: 246 ALTGLFPVDETLRQWYEYRLTR-LPQPHARVNDGTVAALKD---AVQADTDAKYAKNLTI 301

Query: 302 DLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDL 361
           DL+TL+ ++SGPNSVKV N++ DLS QDIKINKAYLVSCTNSRLSD+++AA+V+      
Sbjct: 302 DLSTLSPFLSGPNSVKVYNSLADLSAQDIKINKAYLVSCTNSRLSDIEAAANVI------ 355

Query: 362 NKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPG 421
            K NKVA GVEFYVAAASS ++ DA  SGAW+ L+ AG  PLP+GCGPCIGLG GLLE G
Sbjct: 356 -KNNKVAEGVEFYVAAASSFVQKDAEASGAWQTLINAGAKPLPAGCGPCIGLGTGLLEDG 414

Query: 422 EVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEI 481
           EVGISATNRNFKGRMGSKDALAYLASP VVAASAVLGKI  P EV  +      GV + I
Sbjct: 415 EVGISATNRNFKGRMGSKDALAYLASPEVVAASAVLGKIGFPEEVYGSPVPGAKGVSSSI 474

Query: 482 --IENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDD 539
              E    E +  A    P  S  +L+GFP + +GELVLCDADNINTDGIYPGKYTYQDD
Sbjct: 475 SVTEAVEAEADAEAAESDPAPSGGVLDGFPAQITGELVLCDADNINTDGIYPGKYTYQDD 534

Query: 540 VPKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSF 599
           VP+EKMA+VCMENYD +F +K   GDI+VSGFNFGTGSSREQAAT +LA+ + LV++GSF
Sbjct: 535 VPREKMAEVCMENYDPDFGSKTGAGDIIVSGFNFGTGSSREQAATCILARDMQLVIAGSF 594

Query: 600 GNIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSL 659
           GNIFSRNSINNALLTLEIPALI KLR++Y+G P ELTRRTGWF  WDV  A V VT+G  
Sbjct: 595 GNIFSRNSINNALLTLEIPALINKLRKRYEGQPAELTRRTGWFATWDVPAATVTVTDGKN 654

Query: 660 DGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
            GPVIL+QKVGELG+NLQEIIVKGGLEGWVK+QL
Sbjct: 655 -GPVILKQKVGELGQNLQEIIVKGGLEGWVKAQL 687
>gb|AAH26196.1| Aconitase 2, mitochondrial [Homo sapiens]
          Length = 780

 Score =  876 bits (2265), Expect = 0.0,   Method: Composition-based stats.
 Identities = 161/764 (21%), Positives = 286/764 (37%), Gaps = 103/764 (13%)

Query: 2   LRSTTFTRSFHSSR-AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +      ++ +  R    +   L+EKIV  +  +    ++     Y+ ++P      D +
Sbjct: 43  IHYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDAT 102

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN-----------KSEKNLTKYKNIENFAK 108
             +A L+F+  G +K+  PS I    DH I+            K   N   Y  +     
Sbjct: 103 AQMAMLQFISSGLSKVAVPSTI--HCDHLIEAQVGGEKDLRRAKDI-NQEVYNFLATAGA 159

Query: 109 KHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWA 168
           K+ +  +  G GI HQI++E  YA+P  + + +DSH+   GGLG +   +   DA  + A
Sbjct: 160 KYGVGFWKPGSGIIHQIILEN-YAYPGVLLIGTDSHTPNGGGLGGICIRVGGADAVDVMA 218

Query: 169 TGQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPID 228
                 + P V  V+L G L    S KD+I+ + G+          +E+ G  ++++   
Sbjct: 219 GIPWELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGHGVDSISCT 278

Query: 229 HRLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPK 288
              TI NM  E GA + +FP +  +  +     ++   N                     
Sbjct: 279 GMATICNMGAEIGATTSVFPYNHRMKKYLSKTGREDIANLADEFKDH-----------LV 327

Query: 289 ADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDL----SQQDIKIN--KAYLVSCTN 342
            D   HY + + I+L+ L  +++GP +  +++ V ++     ++   ++     + SCTN
Sbjct: 328 PDPGCHYDQLIEINLSELKPHINGPFTPDLAHPVAEVGKVAEKEGWPLDIRVGLIGSCTN 387

Query: 343 SRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIP 402
           S   D+  +A V           K     +F +   S +I A   + G  + L   G I 
Sbjct: 388 SSYEDMGRSAAVAKQALAHGLKCK----SQFTITPGSEQIRATIERDGYAQILRDLGGIV 443

Query: 403 LPSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLG 458
           L + CGPCIG      ++ GE    +++ NRNF GR   + +  A++ SP +V A A+ G
Sbjct: 444 LANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAG 503

Query: 459 KI-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQ 500
            +           +   +         E+P   F   +      P      +       Q
Sbjct: 504 TLKFNPETDYLTGTDGKKFRLEAPDADELPKGEFDPGQDTYQHPPKDSSGQHVDVSPTSQ 563

Query: 501 SVEILEGFPREFSGELV-----------LCDADNINTDGIYPGKYTYQDDVPKEKM-AQV 548
            +++LE F +   G+ +            C  D+I+  G +     + D++    +   +
Sbjct: 564 RLQLLEPFDKW-DGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAI 622

Query: 549 CMENYDAEFRTKVHP------------------GDIVVSGFNFGTGSSREQAATALLAKG 590
            +EN  A                            +V+   N+G GSSRE AA      G
Sbjct: 623 NIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLG 682

Query: 591 INLVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTR-RTGWFLKWDV 647
              +++ SF  I   N     LL L    PA   K+    +   + L     G  L    
Sbjct: 683 GRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLKDFTPGKPL---- 738

Query: 648 ADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
              K ++     +G            +   E    G     +K 
Sbjct: 739 ---KCIIKH--PNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>ref|ZP_00949139.1| aconitate hydratase [Croceibacter atlanticus HTCC2559]
 gb|EAP87278.1| aconitate hydratase [Croceibacter atlanticus HTCC2559]
          Length = 755

 Score =  876 bits (2264), Expect = 0.0,   Method: Composition-based stats.
 Identities = 168/762 (22%), Positives = 296/762 (38%), Gaps = 91/762 (11%)

Query: 2   LRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNL-PEGKVVHSGDYVSIKPAHCMSHDNS 60
           +      R   +     K   L+EKI+ S+  +         S DYV   P      D +
Sbjct: 11  VYDQMTERVDKAREVVGKPLTLSEKILYSHLWDGNATQAFTRSKDYVDFAPDRIACQDAT 70

Query: 61  WPVAL-KFMGLGATKIKNPSQIVTTLDHDIQNK----------SEKNLTKYKNIENFAKK 109
             +AL +FM  G   +  P+ +    DH IQ K          +E +   +  +E+ +KK
Sbjct: 71  AQMALLQFMQAGKPNVAVPTTV--HCDHLIQAKQGAKADLKRANETSNEVFDFLESVSKK 128

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           + I  +  G GI HQ+++E  YAFP  M + +DSH+   GGLG +   +   DA  + A 
Sbjct: 129 YGIGFWKPGAGIIHQVVLEN-YAFPGGMMIGTDSHTVNAGGLGMVAIGVGGADAVDVMAG 187

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P +  V+L G+L    + KD+I+ + G+          IE+ G    ++    
Sbjct: 188 MPWELKFPKLIGVKLTGKLNGWTAAKDVILKVAGILTVKGGTGAIIEYFGPGAKSMSCTG 247

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
           + TI NM  E GA +  F  D+++  + +   +    +    +       L    ++ + 
Sbjct: 248 KGTICNMGAEVGATTSTFGYDESMERFLRATDRSDVADAANAVK----DYLTADPEVYET 303

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQ------DIKINKAYLVSCTNS 343
            +D ++ + + I+L  L  +++GP +  ++  V ++  +       IK++   + SCTNS
Sbjct: 304 PED-YFDEVIEINLDELRPHLNGPFTPDLATPVSEMKDKAKKNDWPIKVDWGLIGSCTNS 362

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              DL  AA +     D     K+    +F +   S +I   A + G  +          
Sbjct: 363 SYEDLTRAASIAKQAVD----KKIVAKSDFGINPGSEQIRYTAERDGILKIFEDLNATIF 418

Query: 404 PSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRM-GSKDALAYLASPAVVAASAVLGK 459
            + CGPCIG      L+  E    + + NRNF  R  G+ +  A++ SP +VAA A+ G+
Sbjct: 419 TNACGPCIGQWDRSDLKGDEKNTIVHSFNRNFSKRADGNPNTHAFVGSPEMVAAIAISGR 478

Query: 460 IS-SP--------------AEVLSTSEIPFSGVKTE---IIENPVVEEEVNAQTEAPKQS 501
           +   P               +V S  E+P  G   E    +E      +V+ +     + 
Sbjct: 479 LDFDPLNDTLLNEDGEEVKLDVPSGIELPPKGFDVEDAGYVEPVSDGSDVDVKVAEDSER 538

Query: 502 VEILEGFPREF-----SGELVL-----CDADNINTDGIYPGKYTYQDDVPKE-KMAQVCM 550
           +++L  F           +L++     C  D+I+  G +     + D++     +  V  
Sbjct: 539 LQLLTPFEPWDGKNLTDAKLLIKAFGKCTTDHISMAGPWLRYRGHLDNISNNCLIGAVNA 598

Query: 551 ENYDAEFRTKVHPGD------------------IVVSGFNFGTGSSREQAATALLAKGIN 592
            N    F      G+                  +VV   N+G GSSRE AA      G+ 
Sbjct: 599 YNKQTNFVKDQLTGEYDAVPKVQRHYKEKGIPTVVVGDHNYGEGSSREHAAMEPRHLGVK 658

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
           +V+  SF  I   N     +L +     A    ++E       +L             D 
Sbjct: 659 VVLVKSFARIHETNLKKQGMLGITFANEADYDLIQEDDTFNFIDLEDFA--------PDK 710

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
           ++ +     DG     +          E   +G     +K Q
Sbjct: 711 QLTIEIVHEDGSKDTIKANHTYNLPQIEWYKEGSALNLIKKQ 752
>ref|XP_001539249.1| homoaconitase, mitochondrial precursor [Ajellomyces capsulatus
           NAm1]
 gb|EDN09687.1| homoaconitase, mitochondrial precursor [Ajellomyces capsulatus
           NAm1]
          Length = 797

 Score =  876 bits (2264), Expect = 0.0,   Method: Composition-based stats.
 Identities = 409/734 (55%), Positives = 499/734 (67%), Gaps = 64/734 (8%)

Query: 20  GQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFMGLGATKIKNPS 79
            Q L EKIVQ Y+V L  GK V SGDYV+I P  CM+HDNSWPVALKFM +GA+K+++  
Sbjct: 65  PQTLVEKIVQKYSVGLAPGKKVRSGDYVTISPYKCMTHDNSWPVALKFMSIGASKLQDRK 124

Query: 80  QIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIEEGYAFPLNMTV 139
           QIV TLDHD+QNKSEKNL KY+ IE FAK H +D YPAGRGIGHQIM+EEGYA+P  + V
Sbjct: 125 QIVMTLDHDVQNKSEKNLLKYQQIEQFAKTHGVDFYPAGRGIGHQIMVEEGYAWPGTLVV 184

Query: 140 ASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQLPQGVSGKDIIV 199
           ASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V   G LP+GV+GKD+IV
Sbjct: 185 ASDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVNFTGVLPKGVTGKDVIV 244

Query: 200 ALCGLFNNDQVLNHAIEFTG--DSLNALPIDHRLTIANMTTEWGALSGLFPVDKTLIDWY 257
           ALCGLF+ D VLNHAIEFTG  +++ +L ID RLTIANMTTEWGAL+G+FPVD  L  W 
Sbjct: 245 ALCGLFDKDDVLNHAIEFTGSEETMRSLAIDDRLTIANMTTEWGALAGIFPVDNILKGWL 304

Query: 258 KNRLQKLGT----------NNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLT 307
           +++                + + R     +  + E  +   ADK A Y+K+L +DL+TL 
Sbjct: 305 RSKATAAAMWVSSVNGLPSSANTRFTHSQLDKVLE--RPLAADKGAKYSKELSLDLSTLA 362

Query: 308 HYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVN-- 365
            YVSGPNSVKV+  +  L  QDIK+NKAYLVSCTNSR SDL +AA V     + N     
Sbjct: 363 PYVSGPNSVKVATPLDKLEAQDIKVNKAYLVSCTNSRASDLAAAAKVFRQAAEKNDGKIP 422

Query: 366 KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGI 425
           K+A GV+FY+AAAS   +  A ++G W+ L++AG  PLP+GCGPCIGLG GLLEPGEVGI
Sbjct: 423 KLADGVKFYIAAASIPEQNAAEEAGDWQVLVEAGAQPLPAGCGPCIGLGTGLLEPGEVGI 482

Query: 426 SATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEI------PFSGVKT 479
           SATNRNFKGRMGS +A AYLASP VVAASA+ G IS P                  G+K 
Sbjct: 483 SATNRNFKGRMGSTEAKAYLASPEVVAASALRGTISGPGWYEKPEGWAGVSRGEGVGIKE 542

Query: 480 E---------------IIENPVVEEEVN---------------------AQTEAPKQSV- 502
           E                ++N V + E                        +      ++ 
Sbjct: 543 EDRMLTAEEAIANVIGQLDNMVEDAEKIYGNEAISSTSTSQPSQQSKQQEEPGTDSSALT 602

Query: 503 EILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCMENYDAEFRTKVH 562
           E+  GFP   SGE++ CDADNINTDGIYPGKYTYQD++  ++MAQVCM NYDA F     
Sbjct: 603 ELFPGFPECVSGEIIFCDADNINTDGIYPGKYTYQDNISTDQMAQVCMSNYDAAFSQLTR 662

Query: 563 PGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINNALLTLEIPALIK 622
            GDI+V+G+NFG GSSREQAATA+LAK I LVV+GSFGNIFSRNSINNAL+ LE+P LI+
Sbjct: 663 AGDILVTGYNFGCGSSREQAATAILAKRIPLVVAGSFGNIFSRNSINNALMGLEVPRLIQ 722

Query: 623 KLREKYQ---GAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVGELGKNLQEI 679
           +LRE +       K LTRRTGW L WDV  +++ V EG  +G      KVGEL  N+QEI
Sbjct: 723 RLRESFSSTGAGKKALTRRTGWTLTWDVRRSRIEVQEG--EGGEKWTHKVGELPPNVQEI 780

Query: 680 IVKGGLEGWVKSQL 693
           I +GGLE WVK+ +
Sbjct: 781 IARGGLEKWVKNAI 794
>emb|CAG38805.1| ACO2 [Homo sapiens]
          Length = 780

 Score =  875 bits (2263), Expect = 0.0,   Method: Composition-based stats.
 Identities = 159/764 (20%), Positives = 284/764 (37%), Gaps = 103/764 (13%)

Query: 2   LRSTTFTRSFHSSR-AWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           +      ++ +  R    +   L+EKIV  +  +    ++     Y+ ++P      D +
Sbjct: 43  IHYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDAT 102

Query: 61  WPVA-LKFMGLGATKIKNPSQIVTTLDHDIQN-----------KSEKNLTKYKNIENFAK 108
             +A L+F+  G +K+  PS I    DH I+            K   N   Y  +     
Sbjct: 103 AQMAMLQFISSGLSKVAVPSTI--HCDHLIEAQVGGEKDLRRAKDI-NQEVYNFLATAGA 159

Query: 109 KHHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWA 168
           K+ +  +  G GI HQI++E  YA+P  + + +DSH+    GLG +   +   DA  + A
Sbjct: 160 KYGVGFWKPGSGIIHQIILEN-YAYPGVLLIGTDSHTPNGDGLGGICIGVGGADAVDVMA 218

Query: 169 TGQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPID 228
                 + P V  V+L G L    S KD+I+ + G+          +E+ G  ++++   
Sbjct: 219 GIPWELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCT 278

Query: 229 HRLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPK 288
              TI NM  E GA + +FP +  +  +     ++   N                     
Sbjct: 279 GMATICNMGAEIGATTSVFPYNHRMKKYLSKTGREDIANLADEFKDH-----------LV 327

Query: 289 ADKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDL----SQQDIKIN--KAYLVSCTN 342
            D   HY + + I+L+ L  +++GP +  +++ V ++     ++   ++     + SCTN
Sbjct: 328 PDPGCHYDQLIEINLSELKPHINGPFTPDLAHPVAEVGKVAEKEGWPLDIRVGLIGSCTN 387

Query: 343 SRLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIP 402
           S   D+  +A V           K     +F +   S +I A   + G  + L   G I 
Sbjct: 388 SSYEDMGRSAAVAKQALAHGLKCK----SQFTITPGSEQIRATIERDGYAQILRDLGGIV 443

Query: 403 LPSGCGPCIGLGAG-LLEPGEVG--ISATNRNFKGRMG-SKDALAYLASPAVVAASAVLG 458
             + CGPCIG      ++ GE    +++ NRNF GR   + +  A++ SP +V A A+ G
Sbjct: 444 PANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAG 503

Query: 459 KI-----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQ 500
            +           +   +         E+P   F   +      P      +       Q
Sbjct: 504 TLKFNPETDYLTGTDGKKFRLEAPDADELPKGEFDPGQDTYQHPPKDSSGQHVDVSPTSQ 563

Query: 501 SVEILEGFPREFSGELV-----------LCDADNINTDGIYPGKYTYQDDVPKEKM-AQV 548
            +++LE F +   G+ +            C  D+I+  G +     + D++    +   +
Sbjct: 564 RLQLLEPFDKW-DGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAI 622

Query: 549 CMENYDAEFRTKVHP------------------GDIVVSGFNFGTGSSREQAATALLAKG 590
            +EN  A                            +V+   N+G GSSRE AA      G
Sbjct: 623 NIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLG 682

Query: 591 INLVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTR-RTGWFLKWDV 647
              +++ SF  I   N     LL L    PA   K+    +   + L     G  L    
Sbjct: 683 GRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLKDFTPGKPL---- 738

Query: 648 ADAKVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
              K ++     +G            +   E    G     +K 
Sbjct: 739 ---KCIIKH--PNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>ref|XP_448693.1| unnamed protein product [Candida glabrata]
 sp|Q6FM51|LYS4_CANGA Homoaconitase, mitochondrial precursor (Homoaconitate hydratase)
 emb|CAG61656.1| unnamed protein product [Candida glabrata CBS 138]
          Length = 689

 Score =  875 bits (2262), Expect = 0.0,   Method: Composition-based stats.
 Identities = 536/687 (78%), Positives = 591/687 (86%), Gaps = 1/687 (0%)

Query: 7   FTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALK 66
             RSFH      +GQNLTEKIVQ Y+V L  GK VHSGDYVSIKPAH MSHDNSWPVALK
Sbjct: 4   LRRSFHVYTRLQRGQNLTEKIVQQYSVGLAPGKRVHSGDYVSIKPAHVMSHDNSWPVALK 63

Query: 67  FMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIM 126
           FM LGA  +K+P QIV TLDHDIQNKS+KNLTKY+NIE+FAKKH ID YPAGRGIGHQIM
Sbjct: 64  FMNLGARTVKDPRQIVNTLDHDIQNKSDKNLTKYRNIESFAKKHGIDFYPAGRGIGHQIM 123

Query: 127 IEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKG 186
           +EEGYAFPLN+TVASDSHSNTYGG+G+LGTP+VRTDAAAIWATGQTWWQIPPVAQVE KG
Sbjct: 124 VEEGYAFPLNLTVASDSHSNTYGGMGALGTPVVRTDAAAIWATGQTWWQIPPVAQVEFKG 183

Query: 187 QLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGL 246
           +L + VSGKDIIVALCG+FN DQVLNHAIEFTGD++  LP+D RLTIANMTTEWGALSGL
Sbjct: 184 KLHESVSGKDIIVALCGVFNKDQVLNHAIEFTGDAIKHLPVDFRLTIANMTTEWGALSGL 243

Query: 247 FPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATL 306
           FPVD TLI+WYKNRL  +   NHPRIN  TI+ LE+KAK+ KAD DA YAKKL+IDL+TL
Sbjct: 244 FPVDDTLINWYKNRLN-IVGPNHPRINETTIKNLEDKAKVFKADSDAVYAKKLVIDLSTL 302

Query: 307 THYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNK 366
           THYVSGPNSVKVSNTVQDL++ +IKINKAYLVSCTN+RLSDL+SAA VVCPTGDL+KVNK
Sbjct: 303 THYVSGPNSVKVSNTVQDLARDNIKINKAYLVSCTNARLSDLESAAKVVCPTGDLSKVNK 362

Query: 367 VAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGIS 426
           VA GVEFY AAASSEIE +A + G W+ LL AGC PLPSGCGPCIGLGAGLLEPGEVGIS
Sbjct: 363 VADGVEFYFAAASSEIEKEAAEKGIWQALLAAGCKPLPSGCGPCIGLGAGLLEPGEVGIS 422

Query: 427 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPV 486
           ATNRNFKGRMGSKDALAYLASPAVVAASAVLG+I SPAEV    ++  SG+  E +    
Sbjct: 423 ATNRNFKGRMGSKDALAYLASPAVVAASAVLGRIGSPAEVWGIEDVKSSGLLAEELACNT 482

Query: 487 VEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMA 546
                   +E     VE+LEGFP E  GELVLCDADN+NTDGIYPGKYTYQDDV +E MA
Sbjct: 483 ETSTATPVSEGSAAKVEMLEGFPEEIVGELVLCDADNVNTDGIYPGKYTYQDDVSRETMA 542

Query: 547 QVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRN 606
           QVCMENYD EF +K + GDI+VSGFNFGTGSSREQAAT+LLAKGINLVV+GSF N FSRN
Sbjct: 543 QVCMENYDGEFGSKANAGDILVSGFNFGTGSSREQAATSLLAKGINLVVAGSFSNTFSRN 602

Query: 607 SINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILE 666
           SINNALLTLEIP L++KLR K++ APKELTRRTGWFLKWDV +AKV VTEGS DG V+LE
Sbjct: 603 SINNALLTLEIPTLVEKLRSKFENAPKELTRRTGWFLKWDVPNAKVYVTEGSPDGQVLLE 662

Query: 667 QKVGELGKNLQEIIVKGGLEGWVKSQL 693
           QKVGELGKNLQEII+KGGLEGWVKSQL
Sbjct: 663 QKVGELGKNLQEIIIKGGLEGWVKSQL 689
>ref|XP_001485749.1| hypothetical protein PGUG_01420 [Pichia guilliermondii ATCC 6260]
 gb|EDK37322.1| hypothetical protein PGUG_01420 [Pichia guilliermondii ATCC 6260]
          Length = 674

 Score =  875 bits (2262), Expect = 0.0,   Method: Composition-based stats.
 Identities = 475/685 (69%), Positives = 558/685 (81%), Gaps = 16/685 (2%)

Query: 9   RSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPVALKFM 68
           R F +    L+GQNLTEKIVQ YAV +  GK V SGDYV+IKPAHCMSHDNSWPVA KFM
Sbjct: 5   RQFSTGLRALRGQNLTEKIVQKYAVGVAPGKKVVSGDYVTIKPAHCMSHDNSWPVATKFM 64

Query: 69  GLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGHQIMIE 128
           GLGATK+K+  Q+V TLDHD+QN+SE N+ KY NIE FA +  ID YPAGRGIGHQIMIE
Sbjct: 65  GLGATKVKDNRQVVCTLDHDVQNRSESNMKKYANIEKFATEQGIDFYPAGRGIGHQIMIE 124

Query: 129 EGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVELKGQL 188
           EGYAFP N+TVASD HSNTYGG+GSLGTPIVRTDAAAIWATGQTWWQIPPVA+VE  G+L
Sbjct: 125 EGYAFPHNLTVASDLHSNTYGGVGSLGTPIVRTDAAAIWATGQTWWQIPPVAKVEFTGEL 184

Query: 189 PQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEWGALSGLFP 248
            +GV+GKD+IVALCG+FN D+VLNHAIEF GD + +LPID+RLTIANMTTEWGALSGLFP
Sbjct: 185 SEGVTGKDVIVALCGVFNQDEVLNHAIEFVGDGVKSLPIDYRLTIANMTTEWGALSGLFP 244

Query: 249 VDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLIIDLATLTH 308
           VD+T+ID+Y+ R+Q+L    H RIN  T+  L   AK   AD DA YAK LI+DL+T++ 
Sbjct: 245 VDQTVIDFYEGRMQRLQ-QPHERINSDTVGKLAANAKEMAADSDAKYAKHLIVDLSTISP 303

Query: 309 YVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGDLNKVNKVA 368
            VSGPNSVKV++++ DL+QQDIKINKAYLVSCTNSRLSD+Q+AAD+V       + + +A
Sbjct: 304 CVSGPNSVKVASSLHDLAQQDIKINKAYLVSCTNSRLSDIQAAADIV-------RGHTIA 356

Query: 369 PGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEPGEVGISAT 428
            GVEFYVAAASS+++ DA  +GAW+ ++ AG  PLP+GCGPCIGLG GLLEPGEVGISAT
Sbjct: 357 DGVEFYVAAASSQVQQDAEAAGAWQTIIDAGAKPLPAGCGPCIGLGTGLLEPGEVGISAT 416

Query: 429 NRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTEIIENPVVE 488
           NRNFKGRMGSKDALAYLASP VVAASA+LG+I  P E+               ++     
Sbjct: 417 NRNFKGRMGSKDALAYLASPEVVAASAILGRIGGPEEISG-----SKIAAPATLKRSTSV 471

Query: 489 EEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQV 548
              +++  A    V+I+ GFP+E +GEL+LC+ADNINTDGIYPGKYTYQDDVPKEKMAQV
Sbjct: 472 STSDSEDSATGAGVDIIPGFPQELTGELILCNADNINTDGIYPGKYTYQDDVPKEKMAQV 531

Query: 549 CMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSI 608
           CMENYD EF +K  PGDI++SG+NFGTGSSREQAATA+LA+G+ LVV+GSFGNIFSRNSI
Sbjct: 532 CMENYDGEFYSKTKPGDIIISGYNFGTGSSREQAATAILARGMQLVVAGSFGNIFSRNSI 591

Query: 609 NNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQK 668
           NNALLTLEIPALI KLR+KY G  KELT RTGWFLKWDV  A+V VT+   D  VI++QK
Sbjct: 592 NNALLTLEIPALIDKLRQKYAG-DKELTIRTGWFLKWDVPKAQVTVTD--ADNKVIMQQK 648

Query: 669 VGELGKNLQEIIVKGGLEGWVKSQL 693
           VGELG NLQ+IIVKGGLEGWVK+Q+
Sbjct: 649 VGELGTNLQDIIVKGGLEGWVKAQI 673
>ref|NP_013407.1| Aconitase, required for the tricarboxylic acid (TCA) cycle and also
           independently required for mitochondrial genome
           maintenance; phosphorylated; component of the
           mitochondrial nucleoid; mutation leads to glutamate
           auxotrophy; Aco1p [Saccharomyces cerevisiae]
 sp|P19414|ACON_YEAST Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase)
           (Aconitase)
 gb|AAB67348.1| Aconitate  hydratase
 gb|EDN59216.1| aconitase [Saccharomyces cerevisiae YJM789]
          Length = 778

 Score =  874 bits (2260), Expect = 0.0,   Method: Composition-based stats.
 Identities = 166/759 (21%), Positives = 280/759 (36%), Gaps = 95/759 (12%)

Query: 3   RSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWP 62
                       +   +     EKI+  +  +     +     Y+ ++P      D +  
Sbjct: 41  YKQNVETLDIVRKRLNRPFTYAEKILYGHLDDPHGQDIQRGVSYLKLRPDRVACQDATAQ 100

Query: 63  VA-LKFMGLGATKIKNPSQIVTTLDHDIQN-----KSEK-----NLTKYKNIENFAKKHH 111
           +A L+FM  G  ++  P  +    DH IQ      K  K     N   Y  + +   K++
Sbjct: 101 MAILQFMSAGLPQVAKPVTV--HCDHLIQAQVGGEKDLKRAIDLNKEVYDFLASATAKYN 158

Query: 112 IDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQ 171
           +  +  G GI HQI++E  YAFP  + + +DSH+   GGLG L   +   DA  + A   
Sbjct: 159 MGFWKPGSGIIHQIVLEN-YAFPGALIIGTDSHTPNAGGLGQLAIGVGGADAVDVMAGRP 217

Query: 172 TWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRL 231
              + P +  V+L G++    S KDII+ L G+          +E+ GD ++        
Sbjct: 218 WELKAPKILGVKLTGKMNGWTSPKDIILKLAGITTVKGGTGKIVEYFGDGVDTFSATGMG 277

Query: 232 TIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADK 291
           TI NM  E GA + +FP +K++I++ +   +    +     +            +  ADK
Sbjct: 278 TICNMGAEIGATTSVFPFNKSMIEYLEATGRGKIADFAKLYHK----------DLLSADK 327

Query: 292 DAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINK------AYLVSCTNSRL 345
           DA Y + + IDL TL  Y++GP +  ++  V  + +  +  N         + SCTNS  
Sbjct: 328 DAEYDEVVEIDLNTLEPYINGPFTPDLATPVSKMKEVAVANNWPLDVRVGLIGSCTNSSY 387

Query: 346 SDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPS 405
            D+  +A +V           +     F V   S +I A   + G  E   + G I L +
Sbjct: 388 EDMSRSASIVKDAAAHG----LKSKTIFTVTPGSEQIRATIERDGQLETFKEFGGIVLAN 443

Query: 406 GCGPCIGLG-AGLLEPGEVG--ISATNRNFKGRM-GSKDALAYLASPAVVAASAVLGKI- 460
            CGPCIG      ++ G+    +S+ NRNF  R  G+    A++ASP +V A A+ G + 
Sbjct: 444 ACGPCIGQWDRRDIKKGDKNTIVSSYNRNFTSRNDGNPQTHAFVASPELVTAFAIAGDLR 503

Query: 461 ----------SSPAEV----LSTSEIP---FSGVKTEIIENPVVEEEVNAQTEAPKQSVE 503
                         E          +P   +   +      P     V  +       ++
Sbjct: 504 FNPLTDKLKDKDGNEFMLKPPHGDGLPQRGYDAGENTYQAPPADRSTVEVKVSPTSDRLQ 563

Query: 504 ILEGFPREF-----SGELVLC-----DADNINTDGIYPGKYTYQDDVPKE-KMAQVCMEN 552
           +L+ F            +++        D+I+  G +     + +++     +  +  EN
Sbjct: 564 LLKPFKPWDGKDAKDMPILIKAVGKTTTDHISMAGPWLKYRGHLENISNNYMIGAINAEN 623

Query: 553 YDAEFRTKVHPG------------------DIVVSGFNFGTGSSREQAATALLAKGINLV 594
             A     V+ G                   +V+   NFG GSSRE AA      G   +
Sbjct: 624 KKANCVKNVYTGEYKGVPDTARDYRDQGIKWVVIGDENFGEGSSREHAALEPRFLGGFAI 683

Query: 595 VSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADAKV 652
           ++ SF  I   N     LL L    PA   K+    +     L                V
Sbjct: 684 ITKSFARIHETNLKKQGLLPLNFKNPADYDKINPDDRIDILGLAELA--------PGKPV 735

Query: 653 VVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKS 691
            +     +G                E    G     +K+
Sbjct: 736 TMRVHPKNGKPWDAVLTHTFNDEQIEWFKYGSALNKIKA 774
>ref|YP_862527.1| aconitate hydratase [Gramella forsetii KT0803]
 emb|CAL67460.1| aconitate hydratase [Gramella forsetii KT0803]
          Length = 755

 Score =  873 bits (2258), Expect = 0.0,   Method: Composition-based stats.
 Identities = 166/762 (21%), Positives = 285/762 (37%), Gaps = 91/762 (11%)

Query: 2   LRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGK-VVHSGDYVSIKPAHCMSHDNS 60
           + S    R   +     K   L+EKI+ S+  +    +      DYV   P      D +
Sbjct: 11  VYSQMAERVNTAREVVGKPLTLSEKILYSHLWDGKANEAYARGKDYVEFSPDRIACQDAT 70

Query: 61  WPVAL-KFMGLGATKIKNPSQIVTTLDHDIQNK----------SEKNLTKYKNIENFAKK 109
             +AL +FM  G  ++  P+ +    DH IQ K          ++ +   +  +E+ + K
Sbjct: 71  AQMALLQFMQAGKKQVAVPTTV--HCDHLIQAKMGAAIDLQSANKSSSEVFDFLESVSNK 128

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           + I  +  G GI HQ+++E  YAFP  M + +DSH+   GGLG +   +   DA  + A 
Sbjct: 129 YGIGFWKPGAGIIHQVVLEN-YAFPGGMMIGTDSHTVNAGGLGMVAIGVGGADAVDVMAG 187

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P +  V+L G+L    S KD+I+ + G+          IE+ G+    L    
Sbjct: 188 MPWELKFPKLIGVKLTGKLSGWTSSKDVILKVAGILTVKGGTGAIIEYFGEGARNLSCTG 247

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
           + TI NM  E GA +  F  D ++  + K   +    +    +        E       A
Sbjct: 248 KGTICNMGAEVGATTSTFGYDDSMERYLKATNRADVADAANEVREHLTGDDE-----VYA 302

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLS------QQDIKINKAYLVSCTNS 343
           + + ++ + + I+L  L  +++GP +  ++  + +++         I ++   + SCTNS
Sbjct: 303 NPEQYFDEVIEINLDELKPHLNGPFTPDLATPISEMATKAKEHDWPINVDWGLIGSCTNS 362

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              DL  AA +     D     KV    +F +   S +I   A + G  +          
Sbjct: 363 SYEDLTRAASIAKQAVD----KKVKAKSDFGINPGSEQIRFTAERDGLLQIFEDLDATIF 418

Query: 404 PSGCGPCIGLGAGLLEPGE---VGISATNRNFKGRM-GSKDALAYLASPAVVAASAVLGK 459
            + CGPCIG        GE     + + NRNF  R  G+ +  A++ SP +VAA A+ G+
Sbjct: 419 TNACGPCIGQWDRSDRKGEEKNTIVHSFNRNFSKRADGNPNTHAFVGSPELVAAIAISGR 478

Query: 460 IS-----------SPAEV----LSTSEIPFSGVKTE---IIENPVVEEEVNAQTEAPKQS 501
           +               EV        E+P  G   E    +        V  +     + 
Sbjct: 479 LDFDPTRDKLMNEDGEEVMLDEPQGIELPTKGFAVEDAGYVAPKEDGGSVEVKVAEDSER 538

Query: 502 VEILEGFPRE----FSGELVL------CDADNINTDGIYPGKYTYQDDVPKE-KMAQVCM 550
           +E+L  F        +G  +L      C  D+I+  G +     + D++     +  +  
Sbjct: 539 LELLTPFEPWDGKNLTGAKLLIKAWGKCTTDHISMAGPWLRYRGHLDNISNNCLIGAINA 598

Query: 551 ENYDAEFRTKVHPGD------------------IVVSGFNFGTGSSREQAATALLAKGIN 592
            N  + F      G+                  +VV   N+G GSSRE AA      G+ 
Sbjct: 599 YNKKSNFVKSQITGEYDGVPAVQREYKKEGIPTVVVGDHNYGEGSSREHAAMEPRHLGVK 658

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
           +V+  SF  I   N     +L L     +    ++E       +L               
Sbjct: 659 VVLVKSFARIHETNLKKQGMLGLTFANESDYDLIQEDDTFNFTDLENFAPDT------PL 712

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
            + +     DG     +          E    G     +K Q
Sbjct: 713 TIEIVH--ADGSKDTIKANHTYNNPQIEWYKHGSALNLIKKQ 752
>ref|ZP_01061488.1| aconitate hydratase [Flavobacterium sp. MED217]
 gb|EAQ48970.1| aconitate hydratase [Leeuwenhoekiella blandensis MED217]
          Length = 754

 Score =  873 bits (2258), Expect = 0.0,   Method: Composition-based stats.
 Identities = 172/762 (22%), Positives = 289/762 (37%), Gaps = 91/762 (11%)

Query: 2   LRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKV-VHSGDYVSIKPAHCMSHDNS 60
           + S    R   +     K   L EKI+ S+  +    K  V   DYV   P      D +
Sbjct: 11  VYSKVAERVDAAREITGKPLTLAEKILYSHLWDGKTDKAFVRGKDYVDFAPDRIACQDAT 70

Query: 61  WPVAL-KFMGLGATKIKNPSQIVTTLDHDIQNK----------SEKNLTKYKNIENFAKK 109
             +AL +FM  G  ++  P+ +    DH IQ K          +E +   +  +E+ + K
Sbjct: 71  AQMALLQFMQAGKKEVAVPTTV--HCDHLIQAKQGAQKDLKRANETSNEVFDFLESVSNK 128

Query: 110 HHIDHYPAGRGIGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWAT 169
           + I  +  G GI HQ+++E  YAFP  M + +DSH+   GGLG +   +   DA  + A 
Sbjct: 129 YGIGFWKPGAGIIHQVVLEN-YAFPGGMMIGTDSHTVNAGGLGMVAIGVGGADAVDVMAG 187

Query: 170 GQTWWQIPPVAQVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDH 229
                + P +  V+L G+L    + KD+I+ + G+          +E+ G     L    
Sbjct: 188 MPWELKFPKLIGVKLTGELNGWTASKDVILKVAGILTVKGGTGAIVEYFGPGAKNLSATG 247

Query: 230 RLTIANMTTEWGALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKA 289
           + TI NM  E GA +  F  D+++  + +   +    +    I        E       A
Sbjct: 248 KGTICNMGAEIGATTSTFGYDESMERFLRATDRADVADAANEIKEYLTGDDE-----VYA 302

Query: 290 DKDAHYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQ------DIKINKAYLVSCTNS 343
           + + ++ + + I+L+ L  +++GP +  ++  V +L ++       IK++   + SCTNS
Sbjct: 303 NPEQYFDEVIEINLSELRPHLNGPFTPDLATPVGELGEKAAKNDWPIKVDWGLIGSCTNS 362

Query: 344 RLSDLQSAADVVCPTGDLNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPL 403
              DL  AA +     D     K+ P  +F +   S +I   A + G  E     G    
Sbjct: 363 SYEDLSRAASIAQQAID----KKLKPKSDFGINPGSEQIRYTAERDGLLEVFENLGATVF 418

Query: 404 PSGCGPCIGLGAGLLEPGE---VGISATNRNFKGRM-GSKDALAYLASPAVVAASAVLGK 459
            + CGPCIG        GE     + + NRNF  R  G+ +  A++ SP +VAA A+ G+
Sbjct: 419 TNACGPCIGQWDRSDRKGEEKNTIVHSFNRNFSKRADGNPNTHAFVGSPEMVAAIAISGR 478

Query: 460 IS-SP--------------AEVLSTSEIPFSGV---KTEIIENPVVEEEVNAQTEAPKQS 501
           +   P               +V    E+P  G    +   +        V     +  + 
Sbjct: 479 LDFDPLNDTLLNEDGEEVKLDVPVGLELPTKGFAVEENGYLAPTEDGSSVEVIVASDSER 538

Query: 502 VEILEGFPR----EFSGELVL------CDADNINTDGIYPGKYTYQDDVPKE-KMAQVCM 550
           +E+L  F      E     +L      C  D+I+  G +     + D++     +  V  
Sbjct: 539 LELLTPFVPIKDSELKEVKLLIKAFGKCTTDHISMAGPWLRYRGHLDNISNNCLIGAVNA 598

Query: 551 ENYDAEFRTKVHPGD------------------IVVSGFNFGTGSSREQAATALLAKGIN 592
            N    F      G+                  IVV   N+G GSSRE AA      G+ 
Sbjct: 599 YNKKTNFVKSQLTGEYGGVPDTQREYKAKGIKTIVVGDHNYGEGSSREHAAMEPRHLGVA 658

Query: 593 LVVSGSFGNIFSRNSINNALLTLEI--PALIKKLREKYQGAPKELTRRTGWFLKWDVADA 650
            V+  SF  I   N     +L L          ++E    +  +        ++    D 
Sbjct: 659 AVLVKSFARIHETNLKKQGMLGLTFANENDYDLIQEDDTFSFLD--------IEEFAPDK 710

Query: 651 KVVVTEGSLDGPVILEQKVGELGKNLQEIIVKGGLEGWVKSQ 692
            + +     DG                    +G     +K Q
Sbjct: 711 PLTIEVTHADGSKDTIMANHTYNDAQIAWYREGSALNLIKKQ 752
>ref|XP_001646008.1| hypothetical protein Kpol_1031p57 [Vanderwaltozyma polyspora DSM
           70294]
 gb|EDO18150.1| hypothetical protein Kpol_1031p57 [Vanderwaltozyma polyspora DSM
           70294]
          Length = 689

 Score =  873 bits (2256), Expect = 0.0,   Method: Composition-based stats.
 Identities = 514/693 (74%), Positives = 575/693 (82%), Gaps = 5/693 (0%)

Query: 1   MLRSTTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNS 60
           MLR   F           +GQNLTEKIVQ YAV LPEGK V SGDYVSI+P++CMSHDNS
Sbjct: 1   MLRFKRFFSEGSI--RLTRGQNLTEKIVQRYAVELPEGKKVFSGDYVSIRPSYCMSHDNS 58

Query: 61  WPVALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRG 120
           WP+ALKFMGLGATK+K P QIV TLDHD+QNKSEKNLTKY+NIENFAKKH    YPAGRG
Sbjct: 59  WPIALKFMGLGATKLKYPDQIVNTLDHDVQNKSEKNLTKYRNIENFAKKHGSHFYPAGRG 118

Query: 121 IGHQIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVA 180
           IGHQIMIEEGYAFPLN+TVASDSHSN YGG+G LGTPIVRTDAA+IWATGQTWWQIPPVA
Sbjct: 119 IGHQIMIEEGYAFPLNLTVASDSHSNIYGGVGCLGTPIVRTDAASIWATGQTWWQIPPVA 178

Query: 181 QVELKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGDSLNALPIDHRLTIANMTTEW 240
           QVELKG+LP GVSGKDIIVALCGLFN+DQVLNHAIEFTGDS+  L ID+RLTIANMTTEW
Sbjct: 179 QVELKGELPTGVSGKDIIVALCGLFNDDQVLNHAIEFTGDSIKNLSIDNRLTIANMTTEW 238

Query: 241 GALSGLFPVDKTLIDWYKNRLQKLGTNNHPRINPKTIRALEEKAKIPKADKDAHYAKKLI 300
           GALSGLFPVD T+I WYK R+ K+G  +   IN K I  LE+ A+  KAD ++ Y KKL 
Sbjct: 239 GALSGLFPVDSTVIQWYKERINKVGEGHI--INSKAIEELEQNAQKLKADSNSKYDKKLT 296

Query: 301 IDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAADVVCPTGD 360
           IDL+TLT+YVSGPNSVK+SN V+DLS+QDIKINKAYLVSCTNSRLSD+++AADVVCPTG+
Sbjct: 297 IDLSTLTYYVSGPNSVKISNPVEDLSKQDIKINKAYLVSCTNSRLSDIEAAADVVCPTGN 356

Query: 361 LNKVNKVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCIGLGAGLLEP 420
           +  V KVAPGV FY+AAASSE+E +AR SGAW+KLLKAGCI LP+GCGPCIGLG GLLE 
Sbjct: 357 IEDVKKVAPGVNFYIAAASSEVEKEARTSGAWDKLLKAGCIALPAGCGPCIGLGTGLLEA 416

Query: 421 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSEIPFSGVKTE 480
           GEVGISATNRNFKGRMGSKDALAYLASPAVVAASA+ GKI SP E L      ++ VKT 
Sbjct: 417 GEVGISATNRNFKGRMGSKDALAYLASPAVVAASALAGKIVSPNEALGIESCKYASVKTS 476

Query: 481 IIENPVVEEEVNAQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDV 540
                      ++        VEILEGFP E SGELV CDADNINTDGIYPGKYTYQDD+
Sbjct: 477 EQILEEETSGTSSGPTEAS-RVEILEGFPSEISGELVFCDADNINTDGIYPGKYTYQDDI 535

Query: 541 PKEKMAQVCMENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFG 600
            KE MA+VCMENYD EF+TK   GDI++SGFNFGTGSSREQAAT +LA+GINLVVSGSFG
Sbjct: 536 SKEMMAEVCMENYDPEFQTKTKTGDIIISGFNFGTGSSREQAATCILARGINLVVSGSFG 595

Query: 601 NIFSRNSINNALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLD 660
           NIFSRNSINN LLT+E+P LI++LR KY+    ELTRRTGWF KWDVA+  V V EGSL 
Sbjct: 596 NIFSRNSINNGLLTVEVPKLIEQLRSKYKDDTPELTRRTGWFFKWDVANKNVTVREGSLT 655

Query: 661 GPVILEQKVGELGKNLQEIIVKGGLEGWVKSQL 693
           G ++ EQ++ ELGKNLQEIIVKGGLEGWVKS+L
Sbjct: 656 GTIVFEQEIPELGKNLQEIIVKGGLEGWVKSKL 688
>gb|EEH41326.1| homoaconitase [Paracoccidioides brasiliensis Pb01]
          Length = 809

 Score =  872 bits (2255), Expect = 0.0,   Method: Composition-based stats.
 Identities = 413/743 (55%), Positives = 501/743 (67%), Gaps = 56/743 (7%)

Query: 4   STTFTRSFHSSRAWLKGQNLTEKIVQSYAVNLPEGKVVHSGDYVSIKPAHCMSHDNSWPV 63
           S   +    S+ A    Q L EKIVQ ++V LP+GK V SGDYV+I P  CM+HDNSWPV
Sbjct: 67  SAILSSIESSTAATPVPQTLVEKIVQRFSVGLPQGKYVRSGDYVTISPYKCMTHDNSWPV 126

Query: 64  ALKFMGLGATKIKNPSQIVTTLDHDIQNKSEKNLTKYKNIENFAKKHHIDHYPAGRGIGH 123
           ALKFM +GA+K+++P Q+V TLDHD+QN+SEKNL KY+ IE FAK H +D YPAGRGIGH
Sbjct: 127 ALKFMSIGASKLQDPKQVVMTLDHDVQNRSEKNLQKYRQIEQFAKTHEVDFYPAGRGIGH 186

Query: 124 QIMIEEGYAFPLNMTVASDSHSNTYGGLGSLGTPIVRTDAAAIWATGQTWWQIPPVAQVE 183
           QIM+EEGYA+P  + VASDSHSN YGG+G LGTP+VRTDAA+IWATG+TWWQIPPVA+V 
Sbjct: 187 QIMVEEGYAWPGTLVVASDSHSNMYGGVGCLGTPVVRTDAASIWATGKTWWQIPPVAKVT 246

Query: 184 LKGQLPQGVSGKDIIVALCGLFNNDQVLNHAIEFTGD--SLNALPIDHRLTIANMTTEWG 241
             G LP+GV+GKD+IVALCGLF+ D VLNHAIEF G   ++ +L ID RLTIANMTTEWG
Sbjct: 247 FTGVLPKGVTGKDVIVALCGLFDKDDVLNHAIEFAGSEATMRSLAIDDRLTIANMTTEWG 306

Query: 242 ALSGLFPVDKTLIDWYKNRLQKLGT--------NNHPRINPKTIRALEEKAKIPKADKDA 293
           AL+GLFPVD  L  W +++               +            +   +   ADK A
Sbjct: 307 ALAGLFPVDSVLKGWLRSKATTAAMWGSSVDGLPSSANTRFTHPLLDKMFEQPLAADKGA 366

Query: 294 HYAKKLIIDLATLTHYVSGPNSVKVSNTVQDLSQQDIKINKAYLVSCTNSRLSDLQSAAD 353
            YAK+L +DL+TL  YVSGPNSVKV++ + +L  QDIK+NKAYLVSCTNSR SDL +AA 
Sbjct: 367 QYAKELYLDLSTLPPYVSGPNSVKVASPLNELEAQDIKVNKAYLVSCTNSRASDLAAAAK 426

Query: 354 VVCPTGDLNKVN--KVAPGVEFYVAAASSEIEADARKSGAWEKLLKAGCIPLPSGCGPCI 411
           V       N     K+A GV+FY+AAAS   +  A ++G W+ L++AG  PLP+GCGPCI
Sbjct: 427 VFKEAAAKNNGKIPKLADGVKFYIAAASIPEQKAAEEAGDWQTLIEAGAEPLPAGCGPCI 486

Query: 412 GLGAGLLEPGEVGISATNRNFKGRMGSKDALAYLASPAVVAASAVLGKISSPAEVLSTSE 471
           GLG GLLEPGEVGISATNRNFKGRMGS DA AYLASP VVAASA+ GKIS P        
Sbjct: 487 GLGTGLLEPGEVGISATNRNFKGRMGSTDAKAYLASPEVVAASALSGKISGPGWYEKPES 546

Query: 472 I------PFSGVKTE---------------IIENPVVEEEVN------------------ 492
                     GVK E                ++N V + E                    
Sbjct: 547 WTGVVRGEGDGVKEEDRMLTAEEAIEKVINQLDNMVEDAEKIFGNESSSSSTSATASPQQ 606

Query: 493 --AQTEAPKQSVEILEGFPREFSGELVLCDADNINTDGIYPGKYTYQDDVPKEKMAQVCM 550
               ++      E+   FP   SGE++ CDADNINTDGIYPGKYTYQD+V + +MA VCM
Sbjct: 607 SKNSSDNSSSLTEVYPDFPSRVSGEIIFCDADNINTDGIYPGKYTYQDNVTRTQMAAVCM 666

Query: 551 ENYDAEFRTKVHPGDIVVSGFNFGTGSSREQAATALLAKGINLVVSGSFGNIFSRNSINN 610
            NYDA F T   PGDI+V+GFNFG GSSREQAATA+LAK I LVV+GSFGNIFSRNSINN
Sbjct: 667 SNYDASFSTLARPGDILVTGFNFGCGSSREQAATAILAKDIPLVVAGSFGNIFSRNSINN 726

Query: 611 ALLTLEIPALIKKLREKYQGAPKELTRRTGWFLKWDVADAKVVVTEGSLDGPVILEQKVG 670
           AL+ LE+P L+ +LRE + G  K LT+RTGW L WDV  + + V EG  +G      +VG
Sbjct: 727 ALMGLEVPRLVSRLREVFGGQGK-LTQRTGWKLTWDVRRSLIEVQEG--EGGPKWTHRVG 783

Query: 671 ELGKNLQEIIVKGGLEGWVKSQL 693
           EL  N+QEII +GGLE WVK+ +
Sbjct: 784 ELPPNVQEIIARGGLEKWVKNAI 806
  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF excluding environmental samples
  from WGS projects
    Posted date:  May 23, 2008  5:56 PM
  Number of letters in database: 883,778,997
  Number of sequences in database:  2,617,685
  
  Database: /host/Blast/data/nr_perl/nr.01
    Posted date:  May 23, 2008  5:54 PM
  Number of letters in database: 976,759,346
  Number of sequences in database:  2,761,413
  
  Database: /host/Blast/data/nr_perl/nr.02
    Posted date:  May 23, 2008  5:48 PM
  Number of letters in database: 374,670,760
  Number of sequences in database:  1,165,270
  
  Database: /host/Blast/data/nr_perl/nr.03
    Posted date:  Apr 28, 2009  5:40 PM
  Number of letters in database: 114,943,120
  Number of sequences in database:  354,819
  
Lambda     K      H
   0.313    0.187    0.595 

Lambda     K      H
   0.267   0.0572    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,180,610,813
Number of Sequences: 6899187
Number of extensions: 848734632
Number of successful extensions: 1440361
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 11384
Number of HSP's successfully gapped in prelim test: 657
Number of HSP's that attempted gapping in prelim test: 1369455
Number of HSP's gapped (non-prelim): 21714
length of query: 693
length of database: 2,350,152,223
effective HSP length: 141
effective length of query: 552
effective length of database: 1,377,366,856
effective search space: 760306504512
effective search space used: 760306504512
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.4 bits)
S2: 84 (36.5 bits)