BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= YEL020C__[Saccharomyces_cerevisiae]
         (560 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           6,899,187 sequences; 2,350,152,223 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|NP_010895.1|  hypothetical protein with low sequence ide...  1132   0.0  
gb|EDN62949.1|  conserved protein [Saccharomyces cerevisiae ...  1129   0.0  
ref|XP_001645482.1|  hypothetical protein Kpol_1061p50 [Vand...   594   e-168
ref|XP_449488.1|  hypothetical protein CAGL0M03245g [Candida...   585   e-165
ref|NP_984806.1|  AEL055Cp [Ashbya gossypii ATCC 10895] >gi|...   539   e-151
emb|CAQ43484.1|  Putative 2-hydroxyacyl-CoA lyase [Zygosacch...   527   e-148
ref|XP_503660.1|  hypothetical protein [Yarrowia lipolytica]...   451   e-125
dbj|BAC86096.1|  unnamed protein product [Homo sapiens]           446   e-123
ref|XP_001213936.1|  conserved hypothetical protein [Aspergi...   428   e-118
ref|XP_001398049.1|  hypothetical protein An16g07490 [Asperg...   424   e-116
ref|XP_001276631.1|  2-hydroxyphytanoyl-CoA lyase, putative ...   420   e-115
ref|XP_001262067.1|  2-hydroxyphytanoyl-CoA lyase, putative ...   416   e-114
ref|XP_747326.1|  2-hydroxyphytanoyl-CoA lyase [Aspergillus ...   416   e-114
ref|XP_001547987.1|  hypothetical protein BC1G_13678 [Botryo...   414   e-114
gb|EEH33762.1|  2-hydroxyacyl-CoA lyase [Paracoccidioides br...   414   e-113
gb|EEH46455.1|  2-hydroxyacyl-CoA lyase [Paracoccidioides br...   414   e-113
ref|XP_001542634.1|  conserved hypothetical protein [Ajellom...   410   e-112
ref|XP_001817668.1|  hypothetical protein [Aspergillus oryza...   400   e-109
ref|XP_001591149.1|  hypothetical protein SS1G_07774 [Sclero...   395   e-108
ref|XP_001244864.1|  hypothetical protein CIMG_04305 [Coccid...   390   e-106
ref|XP_659120.1|  hypothetical protein AN1516.2 [Aspergillus...   389   e-106
ref|XP_418737.2|  PREDICTED: hypothetical protein [Gallus ga...   389   e-106
ref|NP_595484.1|  oxalyl-CoA decarboxylase (predicted) [Schi...   386   e-105
ref|NP_611460.1|  CG11208 CG11208-PA [Drosophila melanogaste...   385   e-105
dbj|BAD72897.1|  unnamed protein product [Drosophila simulan...   385   e-105
ref|NP_001017332.1|  hypothetical protein LOC550086 [Xenopus...   383   e-104
ref|XP_001361932.1|  GA10842-PA [Drosophila pseudoobscura] >...   381   e-104
emb|CAB60200.1|  2-hydroxyphytanoyl-CoA lyase [Homo sapiens]      381   e-104
ref|NP_001086822.1|  MGC82654 protein [Xenopus laevis] >gi|5...   380   e-103
gb|AAF28957.1|AF161397_1  HSPC279 [Homo sapiens]                  380   e-103
ref|XP_001864201.1|  2-hydroxyacyl-CoA lyase 1 [Culex pipien...   379   e-103
ref|NP_036392.2|  2-hydroxyphytanoyl-CoA lyase [Homo sapiens...   379   e-103
ref|XP_001160528.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   379   e-103
ref|XP_001868099.1|  2-hydroxyphytanoyl-coa lyase [Culex pip...   379   e-103
ref|XP_001160421.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   379   e-103
ref|XP_001160179.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   377   e-102
ref|XP_001160475.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   377   e-102
ref|XP_001160323.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   376   e-102
ref|XP_534256.2|  PREDICTED: similar to 2-hydroxyphytanoyl-C...   375   e-102
ref|XP_975143.1|  PREDICTED: similar to CG11208-PA [Triboliu...   374   e-101
ref|NP_001092419.1|  2-hydroxyphytanoyl-CoA lyase [Bos tauru...   370   e-100
ref|XP_001782528.1|  predicted protein [Physcomitrella paten...   369   e-100
gb|EDL24815.1|  2-hydroxyacyl-CoA lyase 1 [Mus musculus]          369   e-100
ref|NP_445945.1|  2-hydroxyacyl-CoA lyase 1 [Rattus norvegic...   369   e-100
ref|NP_064359.2|  2-hydroxyacyl-CoA lyase 1 [Mus musculus] >...   368   e-100
ref|XP_001629607.1|  predicted protein [Nematostella vectens...   367   1e-99
ref|XP_001495031.1|  PREDICTED: similar to 2-hydroxyacyl-CoA...   367   2e-99
emb|CAB65550.1|  2-hydroxyphytanoyl-CoA lyase [Mus musculus]      366   3e-99
ref|XP_001660326.1|  2-hydroxyphytanoyl-coa lyase [Aedes aeg...   363   2e-98
ref|XP_001649370.1|  2-hydroxyphytanoyl-coa lyase [Aedes aeg...   362   4e-98
ref|XP_311576.3|  AGAP010368-PA [Anopheles gambiae str. PEST...   361   7e-98
ref|XP_001160372.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   360   1e-97
ref|XP_001441621.1|  hypothetical protein GSPATT00010458001 ...   355   4e-96
ref|NP_197240.1|  pyruvate decarboxylase family protein [Ara...   352   4e-95
emb|CAC19854.1|  Oxalyl-CoA decarboxylase [Arabidopsis thali...   351   1e-94
ref|XP_629587.1|  hypothetical protein DDBDRAFT_0184361 [Dic...   347   1e-93
emb|CAN69570.1|  hypothetical protein [Vitis vinifera]            347   2e-93
ref|NP_001040193.1|  2-hydroxyphytanoyl-CoA lyase [Bombyx mo...   343   3e-92
ref|NP_998250.1|  2-hydroxyacyl-CoA lyase 1 [Danio rerio] >g...   339   3e-91
emb|CAG12008.1|  unnamed protein product [Tetraodon nigrovir...   337   2e-90
ref|XP_001160228.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   328   7e-88
emb|CAO68769.1|  unnamed protein product [Vitis vinifera]         327   2e-87
ref|NP_001043144.1|  Os01g0505400 [Oryza sativa (japonica cu...   323   3e-86
ref|XP_001606876.1|  PREDICTED: similar to ENSANGP0000001608...   320   3e-85
ref|NP_496455.1|  B0334.3b [Caenorhabditis elegans] >gi|3873...   319   4e-85
ref|NP_496454.1|  B0334.3a [Caenorhabditis elegans] >gi|3873...   318   7e-85
ref|XP_001679402.1|  Hypothetical protein CBG02874 [Caenorha...   313   2e-83
ref|ZP_02958680.1|  hypothetical protein PROSTU_00430 [Provi...   309   4e-82
ref|ZP_01274540.1|  Thiamine pyrophosphate enzyme, C-termina...   306   2e-81
ref|NP_962457.1|  putative oxalyl-CoA decarboxylase [Mycobac...   306   3e-81
ref|YP_001271099.1|  putative oxalyl-CoA decarboxylase [Lact...   304   1e-80
ref|ZP_03847421.1|  oxalyl-CoA decarboxylase [Lactobacillus ...   303   2e-80
ref|YP_814095.1|  putative oxalyl-CoA decarboxylase [Lactoba...   299   4e-79
ref|YP_908186.1|  putative oxalyl-CoA decarboxylase [Mycobac...   299   4e-79
ref|YP_001758213.1|  oxalyl-CoA decarboxylase [Methylobacter...   298   1e-78
ref|YP_001848640.1|  oxalyl-CoA decarboxylase OxcA [Mycobact...   296   2e-78
ref|ZP_03951717.1|  oxalyl-CoA decarboxylase [Lactobacillus ...   295   9e-78
ref|ZP_04006707.1|  oxalyl-CoA decarboxylase [Lactobacillus ...   294   1e-77
ref|ZP_00921475.1|  COG0028: Thiamine pyrophosphate-requirin...   293   2e-77
ref|YP_001744566.1|  thiamine pyrophosphate-dependent enzyme...   293   3e-77
ref|XP_001202799.1|  PREDICTED: similar to MGC82654 protein ...   292   6e-77
ref|YP_001523384.1|  oxalyl-CoA decarboxylase [Azorhizobium ...   291   8e-77
ref|ZP_02188161.1|  hypothetical protein BAL199_21019 [alpha...   290   2e-76
ref|NP_769797.1|  putative oxalyl-CoA decarboxylase [Bradyrh...   290   2e-76
gb|EAY74225.1|  hypothetical protein OsI_002072 [Oryza sativ...   287   1e-75
ref|YP_001415401.1|  thiamine pyrophosphate protein TPP bind...   286   3e-75
ref|YP_552586.1|  putative oxalyl-CoA decarboxylase [Burkhol...   286   4e-75
ref|YP_001206874.1|  putative oxalyl-CoA decarboxylase [Brad...   285   5e-75
ref|ZP_01879161.1|  hypothetical protein RTM1035_12713 [Rose...   285   6e-75
gb|ABG35151.1|  oxalyl-CoA decarboxylase [Acetobacter aceti]      285   8e-75
ref|YP_001239138.1|  putative oxalyl-CoA decarboxylase [Brad...   285   9e-75
ref|ZP_02120183.1|  oxalyl-CoA decarboxylase [Methylobacteri...   284   1e-74
ref|NP_754791.1|  putative oxalyl-CoA decarboxylase [Escheri...   283   3e-74
gb|EDT30901.1|  oxalyl-CoA decarboxylase [Oligotropha carbox...   282   4e-74
gb|EEH87523.1|  conserved hypothetical protein [Escherichia ...   282   4e-74
ref|ZP_01037465.1|  hypothetical protein ROS217_15790 [Roseo...   281   1e-73
ref|YP_001890405.1|  oxalyl-CoA decarboxylase [Burkholderia ...   281   1e-73
ref|ZP_00721947.1|  COG0028: Thiamine pyrophosphate-requirin...   281   1e-73
ref|YP_541702.1|  putative oxalyl-CoA decarboxylase [Escheri...   281   1e-73
ref|YP_408788.1|  putative oxalyl-CoA decarboxylase [Shigell...   280   2e-73
ref|YP_001463710.1|  thiamine pyrophosphate-dependent enzyme...   280   2e-73
ref|YP_001724289.1|  oxalyl-CoA decarboxylase [Escherichia c...   280   2e-73
ref|YP_001352089.1|  oxalyl-CoA decarboxylase [Janthinobacte...   280   3e-73
ref|NP_288943.1|  putative oxalyl-CoA decarboxylase [Escheri...   280   3e-73
ref|ZP_00927001.1|  COG0028: Thiamine pyrophosphate-requirin...   280   3e-73
ref|ZP_00710336.1|  COG0028: Thiamine pyrophosphate-requirin...   280   3e-73
ref|YP_404126.1|  putative oxalyl-CoA decarboxylase [Shigell...   280   3e-73
ref|NP_708244.1|  putative oxalyl-CoA decarboxylase [Shigell...   279   4e-73
ref|YP_001881182.1|  oxalyl-CoA decarboxylase [Shigella boyd...   279   5e-73
ref|YP_001098706.1|  putative oxalyl-CoA decarboxylase [Herm...   279   5e-73
ref|ZP_00719753.1|  COG0028: Thiamine pyrophosphate-requirin...   279   6e-73
ref|YP_549614.1|  putative oxalyl-CoA decarboxylase [Polarom...   278   9e-73
ref|YP_001155419.1|  putative oxalyl-CoA decarboxylase [Poly...   278   1e-72
ref|YP_001923856.1|  oxalyl-CoA decarboxylase [Methylobacter...   277   1e-72
ref|NP_853789.1|  putative oxalyl-CoA decarboxylase [Mycobac...   276   3e-72
ref|YP_298857.1|  putative oxalyl-CoA decarboxylase [Ralston...   275   1e-71
ref|ZP_00877048.1|  COG0028: Thiamine pyrophosphate-requirin...   275   1e-71
ref|ZP_02917880.1|  hypothetical protein BIFDEN_01177 [Bifid...   274   1e-71
ref|YP_001770851.1|  oxalyl-CoA decarboxylase [Methylobacter...   274   2e-71
ref|NP_214632.1|  putative oxalyl-CoA decarboxylase [Mycobac...   274   2e-71
gb|EAY61578.1|  oxalyl-CoA decarboxylase oxcA [Mycobacterium...   274   2e-71
ref|ZP_02549567.1|  putative oxalyl-CoA decarboxylase [Mycob...   273   3e-71
ref|YP_001638682.1|  oxalyl-CoA decarboxylase [Methylobacter...   272   5e-71
ref|YP_001859803.1|  oxalyl-CoA decarboxylase [Burkholderia ...   270   2e-70
ref|YP_841227.1|  putative oxalyl-CoA decarboxylase [Ralston...   264   1e-68
ref|ZP_04021100.1|  oxalyl-CoA decarboxylase [Lactobacillus ...   264   2e-68
dbj|BAF52673.1|  oxalyl-CoA decarboxylase [Lactobacillus aci...   263   3e-68
sp|P40149|OXC_OXAFO  Oxalyl-CoA decarboxylase >gi|82408223|p...   263   3e-68
ref|YP_193318.1|  putative oxalyl-CoA decarboxylase [Lactoba...   263   4e-68
ref|YP_884573.1|  putative oxalyl-CoA decarboxylase [Mycobac...   260   2e-67
ref|ZP_03995673.1|  oxalyl-CoA decarboxylase [Lactobacillus ...   255   6e-66
ref|YP_889543.1|  putative oxalyl-CoA decarboxylase [Mycobac...   253   2e-65
ref|ZP_02964128.1|  thiamine pyrophosphate-dependent enzyme ...   248   8e-64
ref|XP_001082965.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   247   2e-63
ref|XP_001160268.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   244   2e-62
ref|ZP_03846096.1|  oxalyl-CoA decarboxylase [Lactobacillus ...   241   1e-61
ref|ZP_04012429.1|  oxalyl-CoA decarboxylase [Lactobacillus ...   241   1e-61
ref|XP_001470771.1|  2-hydroxyphytanoyl-CoA lyase, putative ...   239   4e-61
gb|EAZ12058.1|  hypothetical protein OsJ_001883 [Oryza sativ...   233   2e-59
ref|YP_001850995.1|  acetolactate synthase IlvG [Mycobacteri...   196   4e-48
ref|ZP_02057096.1|  thiamine pyrophosphate enzyme domain pro...   194   2e-47
ref|XP_001015183.2|  Thiamine pyrophosphate enzyme, central ...   192   7e-47
ref|ZP_03973583.1|  oxalyl-CoA decarboxylase [Lactobacillus ...   191   1e-46
ref|YP_906760.1|  hypothetical protein MUL_3039 [Mycobacteri...   191   1e-46
ref|YP_074843.1|  acetolactate synthase-like TPP-requiring e...   189   7e-46
ref|ZP_02550365.1|  hypothetical protein MtubH3_08645 [Mycob...   185   7e-45
ref|NP_216336.1|  hypothetical protein Rv1820 [Mycobacterium...   184   1e-44
ref|YP_001238124.1|  Putative acetolactate synthase (Acetohy...   179   4e-43
ref|YP_001203831.1|  Putative acetolactate synthase (Acetohy...   178   1e-42
ref|YP_001275432.1|  thiamine pyrophosphate enzyme, central ...   177   2e-42
ref|NP_302389.1|  hypothetical protein ML2083 [Mycobacterium...   177   3e-42
ref|ZP_02883794.1|  thiamine pyrophosphate protein TPP bindi...   176   4e-42
ref|NP_630663.1|  TPP-requiring enzyme [Streptomyces coelico...   174   1e-41
ref|YP_001023549.1|  acetolactate synthase-like TPP-requirin...   174   2e-41
ref|YP_001432289.1|  thiamine pyrophosphate protein central ...   173   3e-41
ref|YP_390322.1|  acetolactate synthase [Thiomicrospira crun...   171   1e-40
ref|NP_127022.1|  acetolactate synthase, large subunit [Pyro...   171   1e-40
ref|NP_822995.1|  TPP-requiring enzyme (acetolactate synthas...   171   2e-40
ref|NP_613816.1|  acetolactate synthase catalytic subunit [M...   171   2e-40
ref|YP_162422.1|  acetolactate synthase [Zymomonas mobilis s...   169   8e-40
ref|NP_578664.1|  acetolactate synthase [Pyrococcus furiosus...   168   9e-40
ref|YP_594484.1|  acetolactate synthase [Lawsonia intracellu...   166   6e-39
ref|XP_533890.2|  PREDICTED: similar to ilvB (bacterial acet...   165   7e-39
ref|YP_586494.1|  thiamine pyrophosphate enzyme-like TPP bin...   165   7e-39
emb|CAO67786.1|  unnamed protein product [Vitis vinifera]         165   8e-39
ref|YP_001618777.1|  putative Acetolactate synthase [Sorangi...   164   1e-38
ref|YP_001378281.1|  thiamine pyrophosphate protein central ...   164   2e-38
ref|ZP_03864356.1|  thiamine pyrophosphate-dependent enzyme,...   160   2e-37
ref|ZP_02132122.1|  thiamine pyrophosphate enzyme TPP bindin...   160   4e-37
ref|ZP_01696409.1|  acetolactate synthase, catabolic [Bacill...   159   4e-37
ref|XP_001111713.1|  PREDICTED: similar to ilvB (bacterial a...   159   6e-37
ref|ZP_01274866.1|  Acetolactate synthase, catabolic [Lactob...   157   2e-36
ref|YP_811269.1|  Acetolactate synthase [Oenococcus oeni PSU...   157   3e-36
ref|YP_001158055.1|  hypothetical protein Strop_1207 [Salini...   157   3e-36
ref|ZP_01103871.1|  Pyruvate decarboxylase [gamma proteobact...   155   6e-36
gb|ABI26311.1|  thiamine pyrophosphate-requiring enzyme [Lac...   155   8e-36
ref|ZP_03986666.1|  pyruvate oxidase [Staphylococcus aureus ...   154   1e-35
ref|NP_373063.1|  pyruvate oxidase [Staphylococcus aureus su...   154   1e-35
ref|NP_647277.1|  pyruvate oxidase [Staphylococcus aureus su...   154   1e-35
ref|YP_187345.1|  pyruvate oxidase [Staphylococcus aureus su...   154   2e-35
ref|NP_977279.1|  acetolactate synthase [Bacillus cereus ATC...   154   2e-35
ref|YP_417863.1|  pyruvate oxidase [Staphylococcus aureus RF...   154   2e-35
ref|YP_001270741.1|  acetolactate synthase [Lactobacillus re...   154   2e-35
ref|ZP_02129622.1|  thiamine pyrophosphate enzyme TPP bindin...   153   3e-35
ref|ZP_02584602.1|  acetolactate synthase [Bacillus cereus G...   151   1e-34
ref|ZP_02527011.1|  acetolactate synthase [Bacillus cereus A...   151   1e-34
ref|ZP_01574864.1|  acetolactate synthase, large subunit, bi...   151   1e-34
ref|NP_830669.1|  acetolactate synthase [Bacillus cereus ATC...   151   1e-34
ref|YP_114274.1|  acetolactate synthase [Methylococcus capsu...   151   1e-34
ref|YP_041964.1|  pyruvate oxidase [Staphylococcus aureus su...   151   2e-34
ref|YP_844432.1|  thiamine pyrophosphate enzyme TPP binding ...   150   2e-34
ref|YP_001490085.1|  acetolactate synthase, large subunit [A...   150   3e-34
ref|ZP_02254268.1|  acetolactate synthase [Bacillus cereus A...   150   3e-34
ref|YP_001643658.1|  acetolactate synthase, catabolic [Bacil...   150   4e-34
ref|YP_035115.1|  acetolactate synthase [Bacillus thuringien...   150   4e-34
ref|YP_893667.1|  acetolactate synthase [Bacillus thuringien...   149   4e-34
ref|ZP_02581242.1|  acetolactate synthase [Bacillus cereus B...   149   5e-34
ref|ZP_02604905.1|  acetolactate synthase [Bacillus cereus 0...   149   5e-34
ref|ZP_00235858.1|  acetolactate synthase [Bacillus cereus G...   149   5e-34
ref|YP_082376.1|  acetolactate synthase [Bacillus cereus E33...   149   5e-34
ref|YP_306034.1|  acetolactate synthase [Methanosarcina bark...   149   6e-34
ref|YP_001535999.1|  thiamine pyrophosphate protein domain p...   149   6e-34
ref|NP_843379.1|  acetolactate synthase [Bacillus anthracis ...   149   8e-34
ref|YP_001335718.1|  acetolactate synthase large subunit [Kl...   149   8e-34
ref|ZP_02541905.1|  acetolactate synthase [Bacillus cereus W]     148   9e-34
ref|YP_002748212.1|  acetolactate synthase, catabolic [Bacil...   148   1e-33
ref|ZP_02950785.1|  acetolactate synthase [Clostridium butyr...   148   1e-33
ref|ZP_02588349.1|  acetolactate synthase [Bacillus cereus N...   148   2e-33
sp|P27696|ILVB_KLEPN  Acetolactate synthase, catabolic (ALS)...   147   2e-33
pdb|1OZG|A  Chain A, The Crystal Structure Of Klebsiella Pne...   147   2e-33
ref|NP_500306.1|  T26C12.1 [Caenorhabditis elegans] >gi|7495...   147   2e-33
ref|YP_001516199.1|  acetolactate synthase, large subunit, b...   146   4e-33
ref|ZP_03943076.1|  pyruvate oxidase [Lactobacillus buchneri...   146   4e-33
emb|CAG00949.1|  unnamed protein product [Tetraodon nigrovir...   146   5e-33
ref|YP_692424.1|  acetolactate synthase [Alcanivorax borkume...   146   6e-33
ref|NP_276558.1|  acetolactate synthase catalytic subunit [M...   145   7e-33
ref|NP_796731.1|  acetolactate synthase 3 catalytic subunit ...   145   8e-33
ref|YP_393654.1|  acetolactate synthase 3 catalytic subunit ...   145   8e-33
ref|ZP_01991840.1|  acetolactate synthase, large subunit, bi...   145   9e-33
ref|ZP_02177150.1|  acetolactate synthase large subunit [Hyd...   144   1e-32
ref|NP_070548.1|  acetolactate synthase 3 catalytic subunit ...   144   2e-32
ref|ZP_02478424.1|  acetolactate synthase 3 catalytic subuni...   144   2e-32
ref|YP_001827718.1|  putative thiamine pyrophosphate-requiri...   144   2e-32
ref|ZP_03839740.1|  acetolactate synthase, catabolic [Proteu...   144   2e-32
ref|ZP_03940147.1|  pyruvate oxidase [Lactobacillus brevis s...   144   2e-32
ref|ZP_00992427.1|  acetolactate synthase III large subunit ...   144   3e-32
ref|YP_001444053.1|  acetolactate synthase III, large subuni...   144   3e-32
ref|YP_001204647.1|  hypothetical protein BRADO2591 [Bradyrh...   143   3e-32
ref|YP_001529207.1|  thiamine pyrophosphate protein TPP bind...   143   3e-32
ref|YP_001849814.1|  acetolactate synthase (large subunit) I...   143   4e-32
ref|YP_252434.1|  pyruvate oxidase [Staphylococcus haemolyti...   143   4e-32
ref|ZP_01111426.1|  hypothetical protein MADE_06515 [Alterom...   143   4e-32
ref|YP_205646.1|  acetolactate synthase III, large subunit [...   143   4e-32
ref|ZP_02164227.1|  thiamine pyrophosphate enzyme-like TPP-b...   142   5e-32
ref|ZP_03981935.1|  acetolactate synthase [Enterococcus faec...   142   5e-32
ref|ZP_02233750.1|  hypothetical protein DORFOR_00602 [Dorea...   142   5e-32
ref|ZP_02196570.1|  acetolactate synthase III large subunit ...   142   6e-32
gb|EAW64253.1|  phytanoyl-CoA 2-hydroxylase 2, isoform CRA_c...   142   6e-32
ref|ZP_01066405.1|  acetolactate synthase III large subunit ...   142   6e-32
ref|ZP_02961406.1|  hypothetical protein PROSTU_03434 [Provi...   142   7e-32
ref|NP_925750.1|  acetolactate synthase [Gloeobacter violace...   142   7e-32
ref|ZP_00604995.1|  Pyruvate decarboxylase [Enterococcus fae...   142   8e-32
ref|YP_906256.1|  acetolactate synthase [Mycobacterium ulcer...   142   8e-32
ref|ZP_01986889.1|  acetolactate synthase, large subunit, bi...   142   8e-32
ref|NP_765658.1|  pyruvate oxidase [Staphylococcus epidermid...   141   1e-31
ref|ZP_01623421.1|  acetolactate synthase [Lyngbya sp. PCC 8...   141   2e-31
ref|YP_001243976.1|  acetolactate synthase, large subunit, b...   141   2e-31
ref|YP_433431.1|  acetolactate synthase [Hahella chejuensis ...   141   2e-31
ref|NP_350234.1|  acetolactate synthase [Clostridium acetobu...   141   2e-31
ref|YP_447088.1|  IlvB1 [Methanosphaera stadtmanae DSM 3091]...   140   2e-31
ref|YP_001930430.1|  acetolactate synthase, large subunit, b...   140   2e-31
gb|EDN13953.1|  acetolactate synthase III, large subunit [Vi...   140   2e-31
ref|YP_001761044.1|  thiamine pyrophosphate protein TPP bind...   140   2e-31
ref|YP_001406720.1|  acetolactate synthase, large subunit, b...   140   2e-31
ref|ZP_00518644.1|  Pyruvate decarboxylase:Pyruvate decarbox...   140   2e-31
ref|ZP_02902899.1|  acetolactate synthase, large subunit, is...   140   2e-31
ref|YP_001476982.1|  acetolactate synthase, large subunit, b...   140   2e-31
ref|ZP_02939607.1|  thiamine pyrophosphate protein TPP bindi...   140   3e-31
ref|YP_850223.1|  acetolactate synthase [Listeria welshimeri...   140   3e-31
ref|YP_804735.1|  Pyruvate oxidase or other thiamine pyropho...   140   3e-31
ref|ZP_01485182.1|  hypothetical protein VchoV5_02002207 [Vi...   140   3e-31
ref|ZP_03931109.1|  acetolactate synthase [Anaerococcus tetr...   140   3e-31
ref|NP_232112.1|  acetolactate synthase 3 catalytic subunit ...   140   4e-31
ref|YP_001217983.1|  acetolactate synthase 3 catalytic subun...   140   4e-31
ref|YP_001814730.1|  acetolactate synthase, catabolic [Exigu...   140   4e-31
emb|CAJ43227.1|  acetolactate synthase large subunit [Buchne...   140   4e-31
ref|YP_001279514.1|  acetolactate synthase 3 catalytic subun...   139   4e-31
ref|YP_156966.1|  acetolactate synthase [Idiomarina loihiens...   139   4e-31
ref|NP_240056.1|  acetolactate synthase large subunit [Buchn...   139   4e-31
ref|YP_903675.1|  acetolactate synthase, large subunit, bios...   139   5e-31
ref|ZP_01043626.1|  Acetolactate synthase, catabolic, putati...   139   6e-31
ref|ZP_03954292.1|  pyruvate oxidase [Lactobacillus hilgardi...   139   6e-31
ref|ZP_01983141.1|  acetolactate synthase III, large subunit...   139   7e-31
ref|ZP_01944430.1|  acetolactate synthase [Listeria monocyto...   139   7e-31
ref|YP_721656.1|  acetolactate synthase [Trichodesmium eryth...   139   7e-31
ref|YP_300423.1|  pyruvate oxidase [Staphylococcus saprophyt...   139   7e-31
ref|YP_001738428.1|  acetolactate synthase, large subunit, b...   139   8e-31
ref|YP_472891.1|  hypothetical protein RHE_PF00274 [Rhizobiu...   139   9e-31
ref|YP_531571.1|  hypothetical protein RPC_1693 [Rhodopseudo...   139   9e-31
ref|YP_014623.1|  acetolactate synthase [Listeria monocytoge...   138   9e-31
ref|ZP_01927937.1|  acetolactate synthase [Listeria monocyto...   138   1e-30
ref|YP_176141.1|  acetolactate synthase large subunit [Bacil...   138   1e-30
ref|ZP_03870465.1|  acetolactate synthase, large subunit [Ha...   138   1e-30
ref|YP_804144.1|  Pyruvate oxidase or other thiamine pyropho...   138   1e-30
ref|ZP_01261609.1|  acetolactate synthase III large subunit ...   138   1e-30
ref|NP_228358.1|  acetolactate synthase, large subunit [Ther...   138   1e-30
ref|ZP_03827861.1|  acetolactate synthase 3 catalytic subuni...   138   1e-30
ref|YP_922910.1|  hypothetical protein Noca_1710 [Nocardioid...   138   1e-30
ref|NP_471448.1|  acetolactate synthase [Listeria innocua Cl...   138   1e-30
ref|NP_070925.1|  acetolactate synthase, large subunit (ilvB...   138   2e-30
ref|ZP_01482559.1|  hypothetical protein VchoR_02001517 [Vib...   137   2e-30
ref|YP_001433661.1|  thiamine pyrophosphate protein TPP bind...   137   2e-30
ref|ZP_00234236.1|  acetolactate synthase [Listeria monocyto...   137   2e-30
ref|NP_465530.1|  acetolactate synthase [Listeria monocytoge...   137   2e-30
ref|NP_759633.1|  acetolactate synthase 3 catalytic subunit ...   137   2e-30
ref|YP_001735999.1|  acetolactate synthase [Synechococcus sp...   137   2e-30
ref|YP_001805641.1|  acetolactate synthase large subunit [Cy...   137   2e-30
ref|NP_441304.1|  acetolactate synthase [Synechocystis sp. P...   137   3e-30
ref|YP_891991.1|  acetolactate synthase 3 catalytic subunit ...   137   3e-30
ref|YP_001309971.1|  acetolactate synthase [Clostridium beij...   137   3e-30
>ref|NP_010895.1| hypothetical protein with low sequence identity to Pdc1p; Yel020cp
           [Saccharomyces cerevisiae]
 sp|P39994|YEC0_YEAST Putative 2-hydroxyacyl-CoA lyase
 gb|AAB64497.1| Yel020cp [Saccharomyces cerevisiae]
          Length = 560

 Score = 1132 bits (2929), Expect = 0.0,   Method: Composition-based stats.
 Identities = 560/560 (100%), Positives = 560/560 (100%)

Query: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG 60
           MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG
Sbjct: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG 60

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
           YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL
Sbjct: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120

Query: 121 SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
           SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP
Sbjct: 121 SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
           MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP
Sbjct: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP
Sbjct: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR 360
           ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR
Sbjct: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR 360

Query: 361 KEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT 420
           KEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT
Sbjct: 361 KEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT 420

Query: 421 MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE 480
           MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE
Sbjct: 421 MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE 480

Query: 481 KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV 540
           KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV
Sbjct: 481 KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV 540

Query: 541 IIEPGEQKQIAFAWQNKPRL 560
           IIEPGEQKQIAFAWQNKPRL
Sbjct: 541 IIEPGEQKQIAFAWQNKPRL 560
>gb|EDN62949.1| conserved protein [Saccharomyces cerevisiae YJM789]
          Length = 560

 Score = 1129 bits (2919), Expect = 0.0,   Method: Composition-based stats.
 Identities = 557/560 (99%), Positives = 558/560 (99%)

Query: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG 60
           MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG
Sbjct: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG 60

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
           YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL
Sbjct: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120

Query: 121 SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
           SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP
Sbjct: 121 SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
           MILTPN+CGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP
Sbjct: 181 MILTPNLCGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFG SPKWNSESIFIQFDSNP
Sbjct: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGASPKWNSESIFIQFDSNP 300

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR 360
           ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR
Sbjct: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR 360

Query: 361 KEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT 420
           KEKTRG QLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT
Sbjct: 361 KEKTRGTQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT 420

Query: 421 MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE 480
           MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE
Sbjct: 421 MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE 480

Query: 481 KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV 540
           KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV
Sbjct: 481 KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV 540

Query: 541 IIEPGEQKQIAFAWQNKPRL 560
           IIEPGEQKQIAFAWQNKPRL
Sbjct: 541 IIEPGEQKQIAFAWQNKPRL 560
>ref|XP_001645482.1| hypothetical protein Kpol_1061p50 [Vanderwaltozyma polyspora DSM
           70294]
 gb|EDO17624.1| hypothetical protein Kpol_1061p50 [Vanderwaltozyma polyspora DSM
           70294]
          Length = 571

 Score =  594 bits (1532), Expect = e-168,   Method: Composition-based stats.
 Identities = 298/566 (52%), Positives = 405/566 (71%), Gaps = 11/566 (1%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISD 64
           ATQH   +L KY IDT+FGIVGIP+V+LAD+ +AN I+FI  RNEQ+ASYAAS YGY+++
Sbjct: 7   ATQHITDILLKYDIDTIFGIVGIPVVELADSFIANNIRFISFRNEQSASYAASVYGYLNN 66

Query: 65  KPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFL 124
           KPG+LL VGGPGLIH+LAGIYNS+ N+WPL+V+ GS   +D +K GFQELD VSLL   +
Sbjct: 67  KPGILLTVGGPGLIHSLAGIYNSIENKWPLIVLTGSIESTDQYKHGFQELDHVSLLHRHI 126

Query: 125 KFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILT 184
            FT KL+ +NID    +A+        GVS+I++P D        +  D++    P+   
Sbjct: 127 NFTAKLSLENIDRCFYEAMRNSCLINKGVSFIEIPGDLFHSTISTDVIDKSIVHQPISKK 186

Query: 185 PNICGPDPSKIKKVVQLILQHKN---KNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPM 241
                P    I KV + +L++ N   KN L+VIG GA+ +S ++ + +  FNLPF+ TPM
Sbjct: 187 LIEYQPTDELITKVSKFLLENINKNKKNCLVVIGDGAMDDSQKLTKFLTHFNLPFITTPM 246

Query: 242 AKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPE 301
           A+GIVPDSS LNV+SARS ALK A+IVL++G +LNWILHFG+S KWN  ++FIQ D++P 
Sbjct: 247 ARGIVPDSSKLNVASARSLALKNAEIVLLIGTKLNWILHFGSSSKWNENTLFIQIDNSPS 306

Query: 302 TLGDNNVSPGADLSIWGDIGLSVTALVEELTR--QDSCWKYSGVKQEIREKIQLNQTRLL 359
            LG NN S G + S++G+I +++  L   L +  ++  W+Y G  + I+ KI+ N+  L 
Sbjct: 307 NLGLNN-SKGLEYSLFGNISVTLDKLSRSLIKFNKNKQWRYQGPTENIKIKIKENEINLK 365

Query: 360 RKEKTRG-AQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTN 418
           +KE     +QLNYN+VYG+LR +++D  TI+V EGANTMDIARISF TD P+ RLD G  
Sbjct: 366 KKESNHSTSQLNYNEVYGSLRKILNDRETIIVMEGANTMDIARISFKTDYPQHRLDCGNL 425

Query: 419 ATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYH 478
           ATMG+GLGYA++ K S P+  VVLIQGDSAFGFS MEIETAVR +L L+I+VMNNSGIY 
Sbjct: 426 ATMGVGLGYAISAKLSRPDKTVVLIQGDSAFGFSGMEIETAVRNKLGLIIIVMNNSGIYK 485

Query: 479 G----EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRE 534
           G    E+  +  LP TAL+++CRYD+VGKGLGAN + +  +++L + F+ AVQ S+  +E
Sbjct: 486 GVPIEERKSDKALPSTALTQDCRYDIVGKGLGANGYLIRDLNQLDKFFKLAVQRSKVNKE 545

Query: 535 TSVINVIIEPGEQKQIAFAWQNKPRL 560
           TS++NVI+EPG+QK+++F WQ K RL
Sbjct: 546 TSILNVILEPGKQKKLSFGWQTKARL 571
>ref|XP_449488.1| hypothetical protein CAGL0M03245g [Candida glabrata CBS138]
 emb|CAG62464.1| unnamed protein product [Candida glabrata CBS 138]
          Length = 562

 Score =  585 bits (1508), Expect = e-165,   Method: Composition-based stats.
 Identities = 313/560 (55%), Positives = 399/560 (71%), Gaps = 19/560 (3%)

Query: 6   TQHFAQLLQ-KYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISD 64
           +++ A LL+ +Y +D VFGIVGIP+V+ A  + + GI+FI  RNEQAASYAASAYGY++ 
Sbjct: 8   SRNIASLLKYQYDVDVVFGIVGIPVVEFAQELQSVGIRFIGFRNEQAASYAASAYGYLTG 67

Query: 65  KPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFL 124
           KPGVLL+VGGPG+IHALAG+YNSM+NRWPLL+IAGS  + + ++GGFQELDQVSLL P+L
Sbjct: 68  KPGVLLVVGGPGVIHALAGVYNSMNNRWPLLIIAGSVPRDEKYQGGFQELDQVSLLKPYL 127

Query: 125 KFTGKLTPDNIDM-ITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMIL 183
           KF G+LT    D  I   A N   QGT GVSYID P D I     +E  +   +E   I 
Sbjct: 128 KFAGELTGTKKDANIVFNAWNSATQGTPGVSYIDFPGDLI--TDVVEAIEFYKHETKRIT 185

Query: 184 TPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMAK 243
           T    GPDP  I +V  LI +H++KNIL+V+GKG + +S  +R  +  FN PFLPTPMAK
Sbjct: 186 T----GPDPRSIAEVTSLIKEHQDKNILVVLGKGCINSSLALRHFIEEFNFPFLPTPMAK 241

Query: 244 GIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETL 303
           GI+PDS  LNVS+ARSQALK AD+VLV GARLNWILH+ + PKWNS + F+Q D  P TL
Sbjct: 242 GILPDSHRLNVSAARSQALKSADLVLVFGARLNWILHYASPPKWNSNAKFVQVDIEPLTL 301

Query: 304 GDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRL---LR 360
           G NN + G    IWGDI L++  L + L + D   K+ G+ +E++EKI+ N+  L   L 
Sbjct: 302 GVNNPN-GTSYCIWGDIQLTIENLRDTLHKLDFV-KHKGLTKELKEKIESNKHNLRVRLN 359

Query: 361 KEKTRGAQ-LNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNA 419
            E   GA+ LNY  VY  L+ LIDD  + +V+EGANTMDIARISF TD P+RRLDAGTNA
Sbjct: 360 PENYYGAKMLNYYSVYSMLKNLIDDRSSFIVSEGANTMDIARISFETDFPKRRLDAGTNA 419

Query: 420 TMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHG 479
           TMG+GLGYA+A K   PEL++V IQGDSAFGFS MEIETAVR +L ++ ++MNNSGIYHG
Sbjct: 420 TMGVGLGYAIAAKVHSPELNIVTIQGDSAFGFSGMEIETAVRYRLGIIFIIMNNSGIYHG 479

Query: 480 EKDI----EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRET 535
                   E  LPPT LS+ CRYDLV +GLGA  + V  + EL   +++A+  +R +R  
Sbjct: 480 SDPSTITNETQLPPTMLSEKCRYDLVARGLGAKGYLVKNLQELEYYYKKALVHTR-ERIP 538

Query: 536 SVINVIIEPGEQKQIAFAWQ 555
            ++NVIIEPG+ K+I+F WQ
Sbjct: 539 CLLNVIIEPGQNKKISFGWQ 558
>ref|NP_984806.1| AEL055Cp [Ashbya gossypii ATCC 10895]
 gb|AAS52630.1| AEL055Cp [Ashbya gossypii ATCC 10895]
          Length = 545

 Score =  539 bits (1388), Expect = e-151,   Method: Composition-based stats.
 Identities = 279/563 (49%), Positives = 382/563 (67%), Gaps = 21/563 (3%)

Query: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG 60
           M    +   A  L+++GI+ VFGIVGIPIV+LA+ +  +G++FI CRNEQ+ SYAAS YG
Sbjct: 1   MGIQVSDQIAIALKQHGIEVVFGIVGIPIVELAEKLAEHGVRFIACRNEQSCSYAASVYG 60

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
           Y+++KPG LL+VGG G++HALAGI+N+  N+WPLLVIAGS+   D +KGGFQELDQ+ ++
Sbjct: 61  YLTNKPGALLVVGGSGVVHALAGIHNAWVNKWPLLVIAGSTE--DEYKGGFQELDQLRIV 118

Query: 121 SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEK--PLEGNDRTGNE 178
           +P+  F G+L+ DN++ +   A+   +    GVSY+DVP   I  +   PL         
Sbjct: 119 APWTSFKGRLSLDNVNYMVYTAVKTAVL-QHGVSYLDVPGRLINMDAVGPLASK------ 171

Query: 179 LPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLP 238
            P+ +     GPD S+++   +L+     +NIL+V+G+G  +    +R  +  + LPFLP
Sbjct: 172 -PVDIQHVRSGPDSSRVQGAAKLL--QDGRNILVVVGRGCAEYPGVVRSFLERYRLPFLP 228

Query: 239 TPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDS 298
            PMAKGIVPDS  LNV+  RS ALK A+IVLVLGARLNWILH+G++PKWN+++ FIQ D 
Sbjct: 229 VPMAKGIVPDSHELNVNGCRSLALKRAEIVLVLGARLNWILHYGSAPKWNADATFIQVDR 288

Query: 299 NPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRL 358
           +P TLG NN S G + S+  D+ L + A+   L +    W+Y GV  E+ +KI+ N  +L
Sbjct: 289 DPATLGHNN-SSGVNYSVLSDVELFINAITAVLPQS---WQYRGVDNEVLDKIRENGVKL 344

Query: 359 LRKEK-TRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
            RK + T G+ LNY+ VY  LR LIDD  TIL  EGANTMD +R+ F TD P+RRLDAGT
Sbjct: 345 QRKAQLTPGSPLNYHAVYSLLRKLIDDKNTILSAEGANTMDNSRLWFGTDYPKRRLDAGT 404

Query: 418 NATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIY 477
            ATMG+G+GYAL+ K ++P+  VV ++GDSAFGFS ME+ETAVR ++ LV+VVMNN GIY
Sbjct: 405 GATMGLGVGYALSAKLANPDKFVVALEGDSAFGFSCMELETAVRNKVGLVVVVMNNGGIY 464

Query: 478 HGEKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSV 537
           HG     G +  T LS  C Y LVG+GLG N   + T+ EL + F +A+Q S  K  T+V
Sbjct: 465 HGNPG-SGPVRTTDLSPECAYHLVGQGLGCNGVLIRTLDELKKEFPRALQNS-MKSITTV 522

Query: 538 INVIIEPGEQKQIAFAWQNKPRL 560
           +NVI+EPG Q  ++F WQ K  +
Sbjct: 523 LNVILEPGTQTNVSFGWQAKSNM 545
>emb|CAQ43484.1| Putative 2-hydroxyacyl-CoA lyase [Zygosaccharomyces rouxii]
          Length = 504

 Score =  527 bits (1358), Expect = e-148,   Method: Composition-based stats.
 Identities = 276/506 (54%), Positives = 363/506 (71%), Gaps = 27/506 (5%)

Query: 60  GYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSL 119
           GY++ KPGVLL+VGGPG+IHALAGIYNSMSN+WPLLV+AGSS     H+GGFQELDQVSL
Sbjct: 13  GYLTGKPGVLLVVGGPGIIHALAGIYNSMSNKWPLLVLAGSSEAQ--HRGGFQELDQVSL 70

Query: 120 LSPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNEL 179
           L P++KF+G+L   NID++T  AL      TAG +Y+D+P + I       G+    + L
Sbjct: 71  LKPYVKFSGQLNSSNIDVLTYDALRLVQYTTAGATYLDIPGNLI-------GSTVKKDSL 123

Query: 180 P---MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPF 236
           P    I  P    PDPS +++V  LI ++  +N+L+V+GKGAV  S EIR+ V+ F LPF
Sbjct: 124 PPVKNIYVPK-SSPDPSAVQEVTDLIRKNP-ENVLVVVGKGAVHASQEIRQFVDRFQLPF 181

Query: 237 LPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQF 296
           LPTPM KG+VPDS PLNVSSARS+AL+ A +VLVLGARLNWILHF ++PKWN +++FIQ 
Sbjct: 182 LPTPMGKGVVPDSHPLNVSSARSRALQEAKVVLVLGARLNWILHFASAPKWNPDALFIQV 241

Query: 297 DSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQT 356
           DS+  TLG NN      LS+WGDIGL+V  +   L    S     G+   ++  I  N  
Sbjct: 242 DSDTTTLGHNNFK-SQHLSLWGDIGLTVRLITASLGDYHS----QGLSPSLQSNIARNAA 296

Query: 357 RLLRKEKTR-GAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDA 415
           +L  +E  +  ++LNYN VY  LRPLI+D  TI+V+EGANTMD AR+SFPTD P +RLDA
Sbjct: 297 KLKSQESQQVSSRLNYNVVYAHLRPLINDESTIIVSEGANTMDKARVSFPTDYPLQRLDA 356

Query: 416 GTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSG 475
           GTNATMG+G+GYALA K S+P+  V++IQGDSAFGFSAM+IETA R  LAL+++VMNN G
Sbjct: 357 GTNATMGVGMGYALAAKVSNPDKTVLVIQGDSAFGFSAMDIETATRSGLALIVIVMNNGG 416

Query: 476 IYHGEK------DIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLS 529
           IYHG+            LP TAL++ CRYDLV KGLGA+ + V T+++L   F +A + +
Sbjct: 417 IYHGQNPTSSPSSSPSPLPSTALTEECRYDLVAKGLGAHGYLVQTLNDLRESFVKAQEHA 476

Query: 530 RTKRETSVINVIIEPGEQKQIAFAWQ 555
           + K +++++NV++EPGEQK+I+F WQ
Sbjct: 477 K-KGQSTLLNVVLEPGEQKKISFGWQ 501
>ref|XP_503660.1| hypothetical protein [Yarrowia lipolytica]
 emb|CAG79242.1| unnamed protein product [Yarrowia lipolytica CLIB122]
          Length = 562

 Score =  451 bits (1160), Expect = e-125,   Method: Composition-based stats.
 Identities = 257/561 (45%), Positives = 354/561 (63%), Gaps = 24/561 (4%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISD 64
            +Q  A+ L + G++ +FGIVGIP++++AD  +A GIKFI  RNEQ+ASYAAS YGY+S 
Sbjct: 3   GSQVIAESLVQLGVEHIFGIVGIPVIEVADACIARGIKFIGFRNEQSASYAASIYGYLSG 62

Query: 65  KPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFL 124
           KPGV L VGGPG++HALAG+ N+ SN +PLL++AGS    + HKGGFQELDQV+ ++ + 
Sbjct: 63  KPGVCLTVGGPGVLHALAGVGNAQSNCFPLLLLAGSVDVHNTHKGGFQELDQVAAVTEYT 122

Query: 125 KFTGK-LTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMIL 183
           KF  +  + D +  + +KA      G  G +Y+D+PA+ I+ +   + +      L  + 
Sbjct: 123 KFAARPSSTDALPFLLEKAYRTAYFGRPGATYVDLPANIIQSKDNDQVSFGVLQRLRNVP 182

Query: 184 TPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGA--VKNSHEIRRLVNTFNLPFLPTPM 241
            P   G DP+KI +   LI    +K  L+VIGKGA   K    IRR   + N+ FLPTPM
Sbjct: 183 APRSAG-DPAKIAEAAALI--RASKFPLLVIGKGAAYAKAEPTIRRFQESTNIQFLPTPM 239

Query: 242 AKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPE 301
            KG++ DS+P N+S+ RSQALK AD+V+++G RLNWILH+G +PK++  + FI  D   E
Sbjct: 240 GKGVISDSNPGNMSACRSQALKNADVVILVGTRLNWILHYGDAPKYSENTKFIHIDVCAE 299

Query: 302 TLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLRK 361
            LG+N  +  A+L I GD  L +  L + L      WK   +  EI  K + N     +K
Sbjct: 300 ELGNN--AGQAELGILGDASLVIGQLEDVL----KGWKSPALAPEIAAKREKNVQNATKK 353

Query: 362 EKTRGAQLNYNQVYGTLRPLI----DDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
           E      L Y  V+ +++  I     D + ++V+EGANTMD +R  F    PR RLDAGT
Sbjct: 354 EADHSVPLKYFGVFASIQKTIAEIAKDRKLVIVSEGANTMDNSRSVFGHVEPRTRLDAGT 413

Query: 418 NATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIY 477
           NATMG+GLGYA+A KA  P+  VV ++GDSAFGFSA+E+ETAVR  L +VI VMNNSGIY
Sbjct: 414 NATMGVGLGYAIAAKAYDPKSLVVAVEGDSAFGFSAIEVETAVRDNLPMVIYVMNNSGIY 473

Query: 478 HG---EKDIEGD-LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKR 533
           HG    +  +G  LP TALS + RYD++ + LGA  +FV  I EL    + AVQ +R   
Sbjct: 474 HGVDPARYTDGQPLPSTALSLDTRYDVLAESLGAKGYFVKNIEELEVATKSAVQSNR--- 530

Query: 534 ETSVINVIIEPGEQKQIAFAW 554
              VINVIIE G+ +++ F W
Sbjct: 531 -VCVINVIIESGKDQKLEFGW 550
>dbj|BAC86096.1| unnamed protein product [Homo sapiens]
          Length = 569

 Score =  446 bits (1146), Expect = e-123,   Method: Composition-based stats.
 Identities = 246/564 (43%), Positives = 359/564 (63%), Gaps = 29/564 (5%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+  G+  +FGIVGIP+V++A+  VA GI+FI  RNEQ+A+YAAS YGY+S +PGV 
Sbjct: 13  AQTLKNQGVQVIFGIVGIPVVEVAEACVAAGIRFIGFRNEQSAAYAASIYGYLSGRPGVC 72

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L VGGPG++HALAG+ NS  N WPL++++GS        G FQELDQV     + K++ +
Sbjct: 73  LSVGGPGVVHALAGLLNSKINCWPLILLSGSCETDQTDMGAFQELDQVEAARQYCKYSAR 132

Query: 130 -LTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNI- 187
             + + +  + +KA    + G  G +Y+D+PAD+I+Y  P+  N +  + + +   PN  
Sbjct: 133 PASLEQLPFVIEKAFRTALYGRPGAAYVDLPADYIQY--PIT-NKKVFDAVQVARVPNAP 189

Query: 188 -CGPDPSKIKKVVQLILQHKNKNILIVIGKGA--VKNSHEIRRLVNTFNLPFLPTPMAKG 244
               D + + + V L L+H  K+ LIVIGKGA   +  +EIR LV     PFLPTPM KG
Sbjct: 190 KSMADQTNVHQAVAL-LKHA-KSPLIVIGKGAAYARAENEIRALVEKTQAPFLPTPMGKG 247

Query: 245 IVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLG 304
           ++ DS PL VS+ARS+ALK AD+VL++GARLNWILH+G SP+W+++  FIQ D  PE LG
Sbjct: 248 VISDSHPLCVSAARSKALKDADVVLLIGARLNWILHYGHSPRWSNKVRFIQIDIAPEELG 307

Query: 305 DNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWK---YSGVKQEIREKIQLNQTRLLRK 361
           +N       L + GDI L V+ + + LT + S       SG+  ++++ ++  +T+    
Sbjct: 308 NNRQD---TLPLLGDIQLVVSQITQALTGKLSNINPDYVSGLVNKVKQNVE--KTKTAGS 362

Query: 362 EKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATM 421
           + +  A LNY+  +  ++ L+ +   + V+EGANTMDI R  F    PR RLDAGT ATM
Sbjct: 363 KGSDSAILNYSTAFTVIKSLLPENDIVYVSEGANTMDIGRSYFDVHEPRHRLDAGTGATM 422

Query: 422 GIGLGYALACKASHPELD-VVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE 480
           G+G+GYA+  ++ + +   VV I GDSAFGFSAME+ETA+R +L L+I+V+NN+GIYHG 
Sbjct: 423 GVGMGYAIGAQSYYGDAKRVVSIVGDSAFGFSAMELETAIRSRLPLLIIVINNNGIYHGL 482

Query: 481 KDIE-------GDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKR 533
           +D E       G LP T+LS   RYDL+ +  G   +FV    EL++  ++A+     K 
Sbjct: 483 EDEEYHAALKDGTLPTTSLSVETRYDLISEACGGKGWFVKNRVELAKAVKEALA---AKD 539

Query: 534 ETSVINVIIEPGEQKQIAFAWQNK 557
           +T V+NV+I PG + ++ F W  K
Sbjct: 540 QTCVVNVMIAPGGRTKLDFGWMQK 563
>ref|XP_001213936.1| conserved hypothetical protein [Aspergillus terreus NIH2624]
 gb|EAU35205.1| conserved hypothetical protein [Aspergillus terreus NIH2624]
          Length = 600

 Score =  428 bits (1101), Expect = e-118,   Method: Composition-based stats.
 Identities = 263/611 (43%), Positives = 346/611 (56%), Gaps = 69/611 (11%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L+  GI T+FGIVGIP+V++A+  +  GI+F+  RNEQA SYAAS YGY++
Sbjct: 5   TGAQIIARSLRDLGITTIFGIVGIPVVEIAEEAINLGIRFVAFRNEQACSYAASVYGYMT 64

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+VGGPG++HA+AGI N+ +N +PLLV+AGS+  + + KG FQE+D VSLL+P 
Sbjct: 65  GRPGVCLVVGGPGVLHAMAGIGNASANNFPLLVLAGSAETTVVTKGAFQEMDAVSLLTPH 124

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP-- 180
            KF  + +  D I    + A   C  G AG +++D+PAD I      +G    G  LP  
Sbjct: 125 TKFAVRTSSLDFIPGAIKNAYRTCWYGRAGPTFVDLPADII------QGKSAPGFRLPAP 178

Query: 181 ---MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLP 235
              +I +P     DP+ I K  QL+     +  L++IGKGA     E  I RLV    +P
Sbjct: 179 ENILIPSPPKASGDPALIFKAAQLL--RSARAPLLIIGKGAAYARAEASINRLVEQTQIP 236

Query: 236 FLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQ 295
           FLPTPM KG+V DS PLNVSSARS ALK AD+VLVLGARLNWILHFG  PKW+  +  IQ
Sbjct: 237 FLPTPMGKGVVSDSHPLNVSSARSTALKHADVVLVLGARLNWILHFGEPPKWSPSAKIIQ 296

Query: 296 FDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELT--RQDSCWKYSGVKQEIREKIQL 353
            D   E +G N  S  A+L I GDI      L   L   R D     SG   ++ E  + 
Sbjct: 297 VDICAEEIGRNASS--AELGILGDIERVADQLATSLANWRYDPSGTESGFAAQLAESAKK 354

Query: 354 NQTRLLRKEKT---RGAQLNYNQVY-------GTLRPLIDDYRTILVTEGANTMDIARIS 403
           N+ + L+   T     A L Y + Y        TL PL +D   + V+EGANTMDI+R  
Sbjct: 355 NEAKALKAALTPTPPNAPLTYQRAYHIIKSTLNTLSPL-EDGNIVYVSEGANTMDISRSI 413

Query: 404 FPTDAPRRRLDAGTNATMGIGLGYALA---------CKASHPELDVVLIQGDSAFGFSAM 454
           FP   PR+RLDAGT ATMG+G+GY +A           A      +V ++GDSAFGFSAM
Sbjct: 414 FPLHHPRQRLDAGTYATMGVGMGYIVAAHEAYNAGVANAGSTPKKIVALEGDSAFGFSAM 473

Query: 455 EIETAVRCQLALVIVVMNNSGIYHGEKDIEG---------------------DLPPTALS 493
           EIET  R ++  +I V+NNSGIYHG+   E                       L  T+L 
Sbjct: 474 EIETLARYRIPALIYVINNSGIYHGDTTTEDAWKGLQSQTLANDTKSADGKKGLRSTSLL 533

Query: 494 KNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGEQKQIAFA 553
              RY+++    G   +FV T  EL +   +  Q        +++NV++EPG  K I FA
Sbjct: 534 YETRYEMMATMCGGKGYFVRTEEELEKATHEGFQ----SDTVTLVNVVVEPGIGKSIGFA 589

Query: 554 WQN----KPRL 560
           WQN    KPRL
Sbjct: 590 WQNAKEAKPRL 600
>ref|XP_001398049.1| hypothetical protein An16g07490 [Aspergillus niger]
 emb|CAL00522.1| unnamed protein product [Aspergillus niger]
          Length = 604

 Score =  424 bits (1089), Expect = e-116,   Method: Composition-based stats.
 Identities = 257/605 (42%), Positives = 348/605 (57%), Gaps = 70/605 (11%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L+  G+  +FGIVGIP+V++A+  +  GI+F+  RNEQA SYAAS YGY++
Sbjct: 5   TGAQLIARSLRDLGVTVIFGIVGIPVVEIAEEAINLGIRFVAFRNEQACSYAASVYGYMT 64

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+VGGPG++HALAGI NS +N +PLLV+AGS+  + + KG FQELD +SLL+P 
Sbjct: 65  GRPGVCLVVGGPGVLHALAGIGNSSANNFPLLVLAGSAETTGVTKGAFQELDAISLLTPH 124

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP-- 180
            K   + +  D I    + A   C  G  G +++D+PAD I      +G    G  LP  
Sbjct: 125 TKLAVRASSLDFIPGAVKNAYRTCWYGRPGPTFVDLPADII------QGKSSPGYRLPQP 178

Query: 181 ---MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLP 235
              ++ +P   G DP+ I K  QL+     ++ L+VIGKGA     E  I +LV+   +P
Sbjct: 179 ETLLVPSPPKAGGDPALILKASQLL--RTARSPLLVIGKGAAYARAELGINQLVDQTQIP 236

Query: 236 FLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQ 295
           FLPTPM KG+VPDS PLN SSARS ALK AD+VL+LGARLNWILH+G +PKWN  +  IQ
Sbjct: 237 FLPTPMGKGVVPDSHPLNASSARSAALKHADVVLILGARLNWILHYGEAPKWNPTAKIIQ 296

Query: 296 FDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK----- 350
            D   E +G N  +  A+L I GDIGL V  L+  L    S W YS      ++      
Sbjct: 297 VDICAEEIGRN--AGTAELGILGDIGLVVDQLLSSL----SNWTYSPNPSSTKDNKDTFT 350

Query: 351 --IQLNQTRLLRKEKTRGAQ-------LNYNQVY-------GTLRPLIDDYRTILVTEGA 394
             +  +  R   K +T   +       L Y + Y        TL P  +  + I V+EGA
Sbjct: 351 SILTTSANRNELKAQTAALRPTPPNTPLTYQRAYHIIKSTLNTLSPF-EQGKIIYVSEGA 409

Query: 395 NTMDIARISFPTDAPRRRLDAGTNATMGIGLGY---------ALACKASHPELDVVLIQG 445
           NTMDI+R  FP + PR+RLDAGT ATMG+G+GY         A+   +S  +  +V  +G
Sbjct: 410 NTMDISRSIFPLNHPRQRLDAGTYATMGVGMGYIVAAHEAYNAIPSPSSTKQKKIVAFEG 469

Query: 446 DSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGEKDIEGDL-------------PPTAL 492
           DSAFGFSAMEIET  R ++  +I V+NNSGIYHG+   E D                + L
Sbjct: 470 DSAFGFSAMEIETLARYRIPALIYVVNNSGIYHGDSVSEDDWRVLQGQTVGNDTKSESGL 529

Query: 493 SKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGEQKQIAF 552
               RY+++    G   FFV T  EL R  ++  +     +  +V+NVI+EPG  K+I F
Sbjct: 530 LYETRYEMLATMCGGKGFFVRTEEELERATREGFE----SKCVTVVNVIVEPGIGKEIGF 585

Query: 553 AWQNK 557
           AWQ K
Sbjct: 586 AWQGK 590
>ref|XP_001276631.1| 2-hydroxyphytanoyl-CoA lyase, putative [Aspergillus clavatus NRRL
           1]
 gb|EAW15205.1| 2-hydroxyphytanoyl-CoA lyase, putative [Aspergillus clavatus NRRL
           1]
          Length = 603

 Score =  420 bits (1079), Expect = e-115,   Method: Composition-based stats.
 Identities = 255/610 (41%), Positives = 354/610 (58%), Gaps = 79/610 (12%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L+  G+  +FGIVGIP+V++A+  +  GI+F+  RNEQA SYAAS YGY++
Sbjct: 5   TGAQLIARTLRDLGVTVIFGIVGIPVVEIAEEAIDLGIRFVAFRNEQACSYAASVYGYMT 64

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+VGGPG++HA+AGI NS +N +PLLV+AGS+  S + KG FQE+D +S L+P 
Sbjct: 65  GRPGVCLVVGGPGVLHAMAGIGNSAANNFPLLVLAGSAETSGVSKGAFQEMDAISFLTPH 124

Query: 124 LKFTGKLTPDNIDMI---TQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            KF   + P ++D +    Q A   C  G  G +++D+PAD I      +G    G  LP
Sbjct: 125 TKFA--VRPPSLDYVAGAVQNAYRTCWYGRPGPTFVDLPADLI------QGKSTPGFRLP 176

Query: 181 -----MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFN 233
                ++  P     DP+ I K  QL+     ++ L++IGKGA     E  IRRLV    
Sbjct: 177 EPETLLVPAPPKASGDPASILKAAQLL--RSARSPLLIIGKGAAYARAEGAIRRLVEQTQ 234

Query: 234 LPFLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIF 293
           +PFLPTPM KG+VPDS PLNVSSARS ALK AD+VLVLGARLNWILHFG  PKW+  +  
Sbjct: 235 VPFLPTPMGKGVVPDSHPLNVSSARSAALKHADVVLVLGARLNWILHFGEPPKWSPTAKI 294

Query: 294 IQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY--SGVKQE----I 347
           IQ D + E +G N  +  A+L I GDI L V  L+  L    S W+Y  S V  +    +
Sbjct: 295 IQVDISAEEIGRN--AGTAELGIIGDIDLVVQQLLTSL----SNWRYASSAVPSQYLTLL 348

Query: 348 REKIQLNQTRLLRKE---KTRGAQLNYNQVYGTLRPLI------DDYRTILVTEGANTMD 398
            E  + N+ +  +       + + L Y + +  ++  +      ++   + V+EGANTMD
Sbjct: 349 AESAKKNEAKAQKAAMLPTPKNSPLTYQRAFHIIKSTLNSLTPFEEGNVVYVSEGANTMD 408

Query: 399 IARISFPTDAPRRRLDAGTNATMGIGLGYALA---------CKASHPELDVVLIQGDSAF 449
           I+R  FP + PR+RLDAGT ATMG+G+GY +A            + P+  +V ++GDSAF
Sbjct: 409 ISRSVFPLNHPRQRLDAGTYATMGVGMGYIIAAHEAFNASPASTAKPK-KIVALEGDSAF 467

Query: 450 GFSAMEIETAVRCQLALVIVVMNNSGIYHGE----------------KDIEGD------- 486
           GFSAMEIET  R ++  +I V+NNSGIYHG+                 D + D       
Sbjct: 468 GFSAMEIETMARYRIPALIFVVNNSGIYHGDSASESSWKQLQAQTATNDTKSDGQDDHKK 527

Query: 487 -LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPG 545
            L  T+L    RY+ +G   G   +FV T  EL    ++   LS T    +V+NVI+EPG
Sbjct: 528 GLRSTSLLYETRYEQLGPMCGGKGYFVRTEEELETATREGF-LSDT---VTVVNVIVEPG 583

Query: 546 EQKQIAFAWQ 555
             ++I FAWQ
Sbjct: 584 IGQKIGFAWQ 593
>ref|XP_001262067.1| 2-hydroxyphytanoyl-CoA lyase, putative [Neosartorya fischeri NRRL
           181]
 gb|EAW20170.1| 2-hydroxyphytanoyl-CoA lyase, putative [Neosartorya fischeri NRRL
           181]
          Length = 603

 Score =  416 bits (1068), Expect = e-114,   Method: Composition-based stats.
 Identities = 251/609 (41%), Positives = 350/609 (57%), Gaps = 77/609 (12%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           +  Q  A+ L+  G+  +FGIVGIP++++A++ +  GI+FI  RNEQA SYAAS YGY++
Sbjct: 5   SGAQMIARTLRDLGVTVIFGIVGIPVIEVAESAIDLGIRFIAFRNEQACSYAASVYGYLT 64

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+VGGPG++HALAGI N+ +N +PLLV+AGS+  S + KG FQE+D +S L+P 
Sbjct: 65  GQPGVCLVVGGPGVLHALAGIGNASANNFPLLVLAGSAETSGVTKGAFQEMDAISFLTPH 124

Query: 124 LKFTGKLTPDNIDMI---TQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            KF   + P ++  +    + A   C  G  G +++D+PAD I      +G    G  LP
Sbjct: 125 TKFA--VRPPSLAFVAGAVKNAYRTCWYGRPGPTFVDLPADLI------QGKSAPGFRLP 176

Query: 181 -----MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFN 233
                ++  P     DP+ I K  QL+     +  L++IGKGA     E  IR+LV    
Sbjct: 177 EPEEILVPPPPKASGDPAMILKAAQLL--KAARAPLLIIGKGAAYARAEGGIRKLVEQTQ 234

Query: 234 LPFLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIF 293
           +PFLPTPM KG+VPDS PLNVSSARS ALK AD+VLVLGARLNWILHFG  PKW+  +  
Sbjct: 235 IPFLPTPMGKGVVPDSHPLNVSSARSAALKHADVVLVLGARLNWILHFGEPPKWSPRAKI 294

Query: 294 IQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR----- 348
           IQ D   E +G N  +  A+L I GDI L    +VE+L    S W+Y+      R     
Sbjct: 295 IQVDICAEEIGRN--AGTAELGIVGDIDL----VVEQLLVSLSNWRYASSAAPSRFLALL 348

Query: 349 -EKIQLNQTRLLRKEKT---RGAQLNYNQVYGTLRPLI------DDYRTILVTEGANTMD 398
            E  + N+ +  +   T   + + L Y + +  ++  +      +D   + V+EGANTMD
Sbjct: 349 AESAKKNEAKAQKAAFTPTPKNSPLTYQRAFQIIKTTLNSLAPFEDGNVVYVSEGANTMD 408

Query: 399 IARISFPTDAPRRRLDAGTNATMGIGLGYALACKASHPEL--------DVVLIQGDSAFG 450
           I+R  FP + PR+RLDAGT ATMG+G+GY +A   ++            +V ++GDSAFG
Sbjct: 409 ISRSVFPLNHPRQRLDAGTYATMGVGMGYIIAAHEAYNAFPASTDKPKKIVALEGDSAFG 468

Query: 451 FSAMEIETAVRCQLALVIVVMNNSGIYHGE----------------KDIEGD-------- 486
           FSAMEIET  R ++  +I V+NNSGIYHG+                 D + D        
Sbjct: 469 FSAMEIETMARYRIPALIFVVNNSGIYHGDSASESSWKELQAQTAANDTKSDGRDDGKKG 528

Query: 487 LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGE 546
           L  T+L    RY+  G   G   +FV +  EL    ++   LS T    +V+NVI+EPG 
Sbjct: 529 LRSTSLLYETRYEQFGPMCGGKGYFVRSEEELETATREGF-LSDT---VTVVNVIVEPGV 584

Query: 547 QKQIAFAWQ 555
            K+I FAWQ
Sbjct: 585 GKKIGFAWQ 593
>ref|XP_747326.1| 2-hydroxyphytanoyl-CoA lyase [Aspergillus fumigatus Af293]
 gb|EAL85288.1| 2-hydroxyphytanoyl-CoA lyase, putative [Aspergillus fumigatus
           Af293]
 gb|EDP48787.1| 2-hydroxyphytanoyl-CoA lyase, putative [Aspergillus fumigatus
           A1163]
          Length = 655

 Score =  416 bits (1068), Expect = e-114,   Method: Composition-based stats.
 Identities = 250/609 (41%), Positives = 350/609 (57%), Gaps = 77/609 (12%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L+  G+  +FGIVGIP++++A++ +  GI+FI  RNEQA SYAAS YGY++
Sbjct: 57  TGAQLIARTLRDLGVTVIFGIVGIPVIEIAESAIDLGIRFIAFRNEQACSYAASVYGYLT 116

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+VGGPG++HALAGI N+ +N +PLLV+AGS+  S + KG FQE+D +S L+P 
Sbjct: 117 GQPGVCLVVGGPGVLHALAGIGNASANNFPLLVLAGSAETSGVTKGAFQEMDAISFLTPH 176

Query: 124 LKFTGKLTPDNIDMI---TQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            KF   + P ++  +    + A   C  G  G +++D+PAD I      +G    G  LP
Sbjct: 177 TKFA--VRPPSLAFVAGAVKNAYRTCWYGRPGPTFVDLPADLI------QGKSAPGFHLP 228

Query: 181 -----MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFN 233
                ++  P     DP+ I K  QL+     +  L++IGKGA     E  IR+LV    
Sbjct: 229 QPEEILVPPPPKASGDPAMILKAAQLL--KAARAPLLIIGKGAAYARAEGGIRKLVEQTQ 286

Query: 234 LPFLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIF 293
           +PFLPTPM KG+VPDS PLNVSSARS ALK AD+VLVLGARLNWILHFG  PKW+S +  
Sbjct: 287 IPFLPTPMGKGVVPDSHPLNVSSARSAALKHADVVLVLGARLNWILHFGEPPKWSSRAKI 346

Query: 294 IQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQE------I 347
           IQ D   E +G N  +  A+L I GDI L V  L+  L    S W+Y+           +
Sbjct: 347 IQVDICAEEIGRN--AGTAELGIVGDIDLVVQQLLVSL----SNWRYASSAAPSQFLALL 400

Query: 348 REKIQLNQTRLLRKEKT---RGAQLNYNQVYGTLRPLI------DDYRTILVTEGANTMD 398
            +  + N+ +  +   T   + + L Y + +  ++  +      +D   + V+EGANTMD
Sbjct: 401 ADSAKKNEAKAQKAAFTPTPKNSPLTYQRAFQIIKTTLNSLAPFEDGNVVYVSEGANTMD 460

Query: 399 IARISFPTDAPRRRLDAGTNATMGIGLGYALACKASHPEL--------DVVLIQGDSAFG 450
           I+R  FP + PR+RLDAGT ATMG+G+GY +A   ++            +V ++GDSAFG
Sbjct: 461 ISRSVFPLNHPRQRLDAGTYATMGVGMGYIIAAHEAYNAFPASTAKPKKIVALEGDSAFG 520

Query: 451 FSAMEIETAVRCQLALVIVVMNNSGIYHGE----------------KDIEGD-------- 486
           FSAMEIET  R ++  +I V+NNSGIYHG+                 D + D        
Sbjct: 521 FSAMEIETMARYRIPALIFVVNNSGIYHGDSASESSWKELQAQTAANDTKSDGRDDGKKG 580

Query: 487 LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGE 546
           L  T+L    RY+  G   G   +FV +  EL    ++   LS T    +V+NVI+EPG 
Sbjct: 581 LRSTSLLYETRYEQFGPMCGGKGYFVRSEEELETATREGF-LSDT---VTVVNVIVEPGI 636

Query: 547 QKQIAFAWQ 555
            K++ FAWQ
Sbjct: 637 GKKVGFAWQ 645
>ref|XP_001547987.1| hypothetical protein BC1G_13678 [Botryotinia fuckeliana B05.10]
 gb|EDN19647.1| hypothetical protein BC1G_13678 [Botryotinia fuckeliana B05.10]
          Length = 588

 Score =  414 bits (1065), Expect = e-114,   Method: Composition-based stats.
 Identities = 245/597 (41%), Positives = 346/597 (57%), Gaps = 58/597 (9%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
           T+   Q  A+ L+  G++ +FG+VGIP+VQ+A+  +A GI+FI  RNEQAASYAA+AYGY
Sbjct: 3   TSNGAQLIARALKDLGVEVIFGLVGIPVVQIAEEAIAVGIRFIAFRNEQAASYAATAYGY 62

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+VGGPG+IHA+AGI N+ +N +P+L++AGSS    I KG FQELD +SLLS
Sbjct: 63  LTGRPGVCLVVGGPGVIHAMAGIVNASANTFPMLLLAGSSETHLITKGAFQELDAISLLS 122

Query: 122 PFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPM 181
           P  K   +   D+I      A      G  G  ++D+PAD I+     EG   +   +P 
Sbjct: 123 PHTKIAVRSNLDSISHSITAAYRTSWYGRPGAGFVDLPADIIQG----EGEYISTQIVPA 178

Query: 182 ILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPT 239
              P   G D   IKKVVQL+   K    L+++GKGA     E  +R+L++  N+PFLPT
Sbjct: 179 --APRAAG-DAESIKKVVQLLKSAKAP--LVIVGKGAAYAQAESVVRQLIDQTNIPFLPT 233

Query: 240 PMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSN 299
           PM KG++PDS P N ++ARS ALK AD+VLVLGARLNWILH+G +PK+N     IQ D +
Sbjct: 234 PMGKGVLPDSHPSNTATARSAALKGADVVLVLGARLNWILHYGEAPKYNPNVKIIQVDIS 293

Query: 300 PETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQT 356
            E +G NN    A+L I GDI + V  L++ L  QD  W+Y   S   + ++     N+ 
Sbjct: 294 AEEIGKNNGD--AELGIIGDINVVVKQLIDSL--QD--WQYDTSSVYIKNLKASTSKNEA 347

Query: 357 RLLRKEKTRGAQLNYNQVYGTLRPLI------DDYRTILVTEGANTMDIARISFPTDAPR 410
              R  K     + Y + +  ++  +       D   + V+EGANTMDI+R +FP + PR
Sbjct: 348 TAARTAKIDKFPMTYGRAFDVIKETVHKLSPPKDGGVVYVSEGANTMDISRSAFPVEHPR 407

Query: 411 RRLDAGTNATMGIGLGYALA--CKASHPELD-----------VVLIQGDSAFGFSAMEIE 457
            RLDAGT+ATMG+GLGYA+A  C  + P  +           ++ ++GDSAFGFS  E+E
Sbjct: 408 LRLDAGTHATMGVGLGYAIAAHCAYNLPSGEARSGPNFSHKKIICLEGDSAFGFSLAEVE 467

Query: 458 TAVRCQLALVIVVMNNSGIYHGEKD---------------IEGDLPPTALSKNCRYDLVG 502
           T  R  + ++I VMNN G+Y G+ +                +G L  T+L     Y  V 
Sbjct: 468 TMARYGMDILIFVMNNGGVYQGDSESSDEWLKLQKNSKMGSKGGLRSTSLGWEVDYQKVA 527

Query: 503 KGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGEQKQIAFAWQNKPR 559
           +  G   F V +  EL++  ++  + S       +INVIIE G QK + FAWQ   +
Sbjct: 528 EMCGGKGFLVRSPDELAKATEEGFKAS----VPVIINVIIEAGAQKTLEFAWQQDSK 580
>gb|EEH33762.1| 2-hydroxyacyl-CoA lyase [Paracoccidioides brasiliensis Pb01]
          Length = 605

 Score =  414 bits (1064), Expect = e-113,   Method: Composition-based stats.
 Identities = 246/603 (40%), Positives = 346/603 (57%), Gaps = 64/603 (10%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L   G+  +FGIVGIP+V++A+  +  GI+FI  RNEQA SYAAS +GY+S
Sbjct: 5   TGAQIVARSLYDLGVSVIFGIVGIPVVEIAEEAINLGIRFIAFRNEQACSYAASVFGYMS 64

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            KPGV L+VGGPG++HA+AGI NS  N +PLLV+AGS+    + KGGFQE+D ++LL+P 
Sbjct: 65  GKPGVCLVVGGPGVLHAMAGIGNSTVNTFPLLVLAGSTETHMVTKGGFQEMDAITLLTPH 124

Query: 124 LKFTGK-LTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
            K   +  +P+++    + A   C  G  G ++ID+PAD I+ + P EG      E  ++
Sbjct: 125 TKLAIRPFSPESVTNAIRNAYRTCWYGRPGTTFIDLPADLIQGKAP-EGFSLPPRERIVV 183

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGA--VKNSHEIRRLVNTFNLPFLPTP 240
            +P     DP  I KV +L+   +    L+V+GKG+   +    I   V    +PFLPTP
Sbjct: 184 PSPPKPSGDPVVISKVARLLKSARAP--LVVVGKGSAYARAESSILEFVEKTGIPFLPTP 241

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG++PDS PLN SSARS ALK AD+V++LGARLNWILHFG +P+W+    FIQ D N 
Sbjct: 242 MGKGVIPDSHPLNTSSARSAALKNADVVILLGARLNWILHFGETPRWSRSVKFIQVDINV 301

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY------------SGVKQEIR 348
           E +G+N  +  A+L I GDI L +  L+  L    S WKY            S +     
Sbjct: 302 EEIGNN--AGDAELGIVGDISLVIQQLLSSL----SNWKYKPSSPTSPNSYPSILAASAS 355

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDY------RTILVTEGANTMDIARI 402
           +    +Q + L   K  G  L Y + Y  ++ +++          + V+EGANTMDI+R 
Sbjct: 356 KNENASQEKALLPTKPNGF-LTYQRTYHIIKTVLNTLSPPEQGNIVYVSEGANTMDISRS 414

Query: 403 SFPTDAPRRRLDAGTNATMGIGLGYALACKASH------------PELDVVLIQGDSAFG 450
           SFP + PR+RLDAGT ATMG+GLGY +A  A++             +  +V ++GDSAFG
Sbjct: 415 SFPVEQPRQRLDAGTYATMGVGLGYIVAAHAAYNLPSSPGEKIPQKQKKIVAMEGDSAFG 474

Query: 451 FSAMEIETAVRCQLALVIVVMNNSGIYHGE---KD---------------IEGDLPPTAL 492
           FSAME+ET  R ++  +I VMNNSGIYHG+   KD                +G L  T+L
Sbjct: 475 FSAMEVETLARHRIPALIFVMNNSGIYHGDTQTKDEWKTLQDETLTSTNVAKGGLRSTSL 534

Query: 493 SKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGEQKQIAF 552
               RY+ +    G   +FV T  EL +  ++           +++NVI+EPG  + I F
Sbjct: 535 LYETRYEHLAAMCGGRGYFVRTEEELEKATREGFL---EDERVTIVNVIVEPGIGQSIQF 591

Query: 553 AWQ 555
            WQ
Sbjct: 592 GWQ 594
>gb|EEH46455.1| 2-hydroxyacyl-CoA lyase [Paracoccidioides brasiliensis Pb18]
          Length = 695

 Score =  414 bits (1063), Expect = e-113,   Method: Composition-based stats.
 Identities = 247/603 (40%), Positives = 345/603 (57%), Gaps = 64/603 (10%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L   G+  +FGIVGIP+V++A+  +  GI+FI  RNEQA SYAAS +GY+S
Sbjct: 95  TGAQIVARSLYDLGVSVIFGIVGIPVVEIAEEAINLGIRFIAFRNEQACSYAASVFGYMS 154

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            KPGV L+VGGPG++HA+AGI NS  N +PLLV+AGS+    + KGGFQE+D ++LL+P 
Sbjct: 155 GKPGVCLVVGGPGVLHAMAGIGNSTVNTFPLLVLAGSAETHMVTKGGFQEMDAITLLTPH 214

Query: 124 LKFTGK-LTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
            K   +  +P+++    + A   C  G  G S+ID+PAD I+ + P EG      E  ++
Sbjct: 215 TKLAIRPFSPESVTNAIRNAYRTCWYGRPGTSFIDLPADLIQGKAP-EGFSLPPRERIVV 273

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGA--VKNSHEIRRLVNTFNLPFLPTP 240
            +P     DP  I KV +L+   +    L+V+GKG+   +    I   V    +PFLPTP
Sbjct: 274 PSPPKPSGDPVVISKVARLLKSARAP--LVVVGKGSAYARAESSILEFVEKTGIPFLPTP 331

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG++PDS PLN SSARS ALK AD+V++LGARLNWILHFG +P+W+    FIQ D N 
Sbjct: 332 MGKGVIPDSHPLNTSSARSAALKNADVVILLGARLNWILHFGETPRWSRSVKFIQVDINV 391

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY------------SGVKQEIR 348
           E +G N  +  A+L I GDI L +  L+  L    S WKY            S +     
Sbjct: 392 EEIGRN--AGDAELGIVGDISLVIQQLLSSL----SNWKYKPSSPTSPNSYPSILAASAS 445

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDY------RTILVTEGANTMDIARI 402
           +    +Q + L   K  G  L Y + Y  ++ +++          + V+EGANTMDI+R 
Sbjct: 446 KNENASQEKALLPTKPNGF-LTYQRSYHIIKTVLNTLSPPEQGNIVYVSEGANTMDISRS 504

Query: 403 SFPTDAPRRRLDAGTNATMGIGLGYALACKASH------------PELDVVLIQGDSAFG 450
           SFP + PR+RLDAGT ATMG+GLGY +A  A++             +  +V ++GDSAFG
Sbjct: 505 SFPLEQPRQRLDAGTYATMGVGLGYIVAAHAAYNLPSSPGEKIPPKQKKIVALEGDSAFG 564

Query: 451 FSAMEIETAVRCQLALVIVVMNNSGIYHGE---KD---------------IEGDLPPTAL 492
           FSAME+ET  R ++  +I VMNNSGIYHG+   KD                +G L  T+L
Sbjct: 565 FSAMEVETLARHRIPALIFVMNNSGIYHGDTQTKDEWKTLQDETLTSTNVAKGGLRSTSL 624

Query: 493 SKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGEQKQIAF 552
               RY+ +    G   +FV T  EL +  ++           +++NVI+EPG  + I F
Sbjct: 625 LYETRYEHLAAMCGGRGYFVRTEEELEKATREGFL---EGERVTIVNVIVEPGIGQSIQF 681

Query: 553 AWQ 555
            WQ
Sbjct: 682 GWQ 684
>ref|XP_001542634.1| conserved hypothetical protein [Ajellomyces capsulatus NAm1]
 gb|EDN06202.1| conserved hypothetical protein [Ajellomyces capsulatus NAm1]
          Length = 604

 Score =  410 bits (1053), Expect = e-112,   Method: Composition-based stats.
 Identities = 241/605 (39%), Positives = 340/605 (56%), Gaps = 65/605 (10%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
           + T  Q  A+ L   G++ +FGIVGIP+V++A+  +  GI+FI  RNEQA SYAAS YGY
Sbjct: 3   SLTGAQIAARSLHGLGVNVIFGIVGIPVVEVAEEAINLGIRFIAFRNEQACSYAASVYGY 62

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           +S KPGV L+VGGPG++H +AGI N+  N +PLLV+AGS+    I KGGFQE+D +SLL+
Sbjct: 63  MSGKPGVCLVVGGPGVLHGIAGIGNAAVNAFPLLVLAGSAESHTITKGGFQEMDAISLLT 122

Query: 122 PFLKFTGKLTPDNIDMIT---QKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNE 178
           P  K    + P +++ +    + A   C  G  G ++ID+PAD I+  K   G      +
Sbjct: 123 PHTKLA--IRPSSLESVNDAIRNAYRTCWYGRPGPTFIDLPADLIQ-GKTAAGFTLPPPK 179

Query: 179 LPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGA--VKNSHEIRRLVNTFNLPF 236
           L ++ +P     DP+ + KV QL+   +    L+V+GKG+   +    IR  V    +PF
Sbjct: 180 LTLVPSPPKSSGDPAVVSKVAQLLKSARAP--LVVVGKGSAYARAESSIREFVERTGIPF 237

Query: 237 LPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQF 296
           LPTPM KG++PDS PLN SSARS ALK AD+VL+ GARLNWILHFG +P+W+     IQ 
Sbjct: 238 LPTPMGKGVIPDSHPLNTSSARSTALKHADVVLLFGARLNWILHFGETPRWSGSVKLIQV 297

Query: 297 DSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKI-QLNQ 355
           D N + +G N  +  A+L I GDI L    L+  L    + W+Y        +    L  
Sbjct: 298 DINAQEIGHN--AGVAELGIVGDINLVAQQLLSSL----AGWQYKPASATSPDSYPSLLA 351

Query: 356 TRLLRKEKT----------RGAQLNYNQVYGTLRPLIDDY------RTILVTEGANTMDI 399
               + E T          R   L + +VY  ++  ++          + V+EGANTMDI
Sbjct: 352 ASATKNENTSQKKALLPTQRNEFLTFQRVYHIIKTTLNSLSPPQEGNIVYVSEGANTMDI 411

Query: 400 ARISFPTDAPRRRLDAGTNATMGIGLGYALACKAS------------HPELDVVLIQGDS 447
           +R +FP + PR+RLDAGTNATMG+GLGY +A  A+            H    +V ++GDS
Sbjct: 412 SRSAFPLEHPRQRLDAGTNATMGVGLGYIVAAHAAYNIPSSPGSTHIHTPKKIVALEGDS 471

Query: 448 AFGFSAMEIETAVRCQLALVIVVMNNSGIYHGEKDIEGD-----------------LPPT 490
           AFGFSAME+ET  R ++  +I +MNNSGIYHG+   EG+                 L  T
Sbjct: 472 AFGFSAMEVETLARHRIPALIFIMNNSGIYHGDTKTEGEWKNLQNETVNEANAKKGLRST 531

Query: 491 ALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGEQKQI 550
           +L    RY+ +    G   +FV T  EL    ++         + +++NVI+EPG  + I
Sbjct: 532 SLLYETRYEYLAAMCGGRGYFVRTEEELEMATREGFL---EDEKVTIVNVIVEPGIGQSI 588

Query: 551 AFAWQ 555
            F WQ
Sbjct: 589 QFGWQ 593
>ref|XP_001817668.1| hypothetical protein [Aspergillus oryzae RIB40]
 dbj|BAE55666.1| unnamed protein product [Aspergillus oryzae]
          Length = 593

 Score =  400 bits (1027), Expect = e-109,   Method: Composition-based stats.
 Identities = 248/604 (41%), Positives = 343/604 (56%), Gaps = 78/604 (12%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L+  G+D +FGIVGIP+V++A+  +  GI+F+  RNEQA SYAAS YGY++
Sbjct: 5   TGAQVIARTLRDVGVDVIFGIVGIPVVEIAEEAINLGIRFVAFRNEQACSYAASVYGYMT 64

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+VGGPG       I N+ +N +PLLV+AGS+  + + KG FQE+D +S L+P 
Sbjct: 65  GRPGVCLVVGGPG-------IGNASANNFPLLVLAGSAETTAVTKGAFQEMDAISFLTPH 117

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP-- 180
            KF  + +  D I    + A   C  G  G +++D+PAD I+      G    G  LP  
Sbjct: 118 TKFAVRTSSIDFIPGAVKNAYRTCWYGRPGPTFVDLPADIIQ------GKSAPGFRLPEP 171

Query: 181 ---MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLP 235
              ++ +P     DP+ I K  QL+     ++ L++IGKGA     E  I RLV    +P
Sbjct: 172 ETLLVPSPPKASGDPALILKATQLL--KTARSPLLIIGKGAAYARAESGIGRLVEQTQIP 229

Query: 236 FLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQ 295
           FLPTPM KG++PDS PLN SSARS ALK AD+VLVLGARLNWILHFG +PKW+ ++  IQ
Sbjct: 230 FLPTPMGKGVIPDSHPLNASSARSTALKQADVVLVLGARLNWILHFGEAPKWSPKAKIIQ 289

Query: 296 FDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQ 355
            D   E +G N  +  A+L I GDI L V  LV  L    S W+Y     E R    L +
Sbjct: 290 VDICAEEIGRN--AGTAELGIVGDIELVVDQLVSSL----SNWRYDPSPAEGRFPTLLAE 343

Query: 356 TRLLRKEKTRGAQLN-------------YNQVYGTLRPL--IDDYRTILVTEGANTMDIA 400
           +    + K + A L              Y+ +  TL  L   ++   + V+EGANTMDI+
Sbjct: 344 SAKKNEAKAQKAALRSTPQNTPLTYQRAYHIIKSTLNSLTPFEEGNIVYVSEGANTMDIS 403

Query: 401 RISFPTDAPRRRLDAGTNATMGIGLGYALACKASH--------PELDVVLIQGDSAFGFS 452
           R  FP + PR+RLDAGT ATMG+G+GY +A   ++        P+  +V ++GDSAFGFS
Sbjct: 404 RSMFPLNHPRQRLDAGTYATMGVGMGYIVAAHEAYNASPGSTKPK-KIVALEGDSAFGFS 462

Query: 453 AMEIETAVRCQLALVIVVMNNSGIYHGE----------------KDIEGD-----LPPTA 491
           AMEIET  R ++  +I V+NNSGIYHG+                 D + D     L  T+
Sbjct: 463 AMEIETLARYKIPALIYVVNNSGIYHGDTTTEDAWKTLQEQTVANDTKSDDGKKGLRSTS 522

Query: 492 LSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGEQKQIA 551
           L    RY+++    G   +FV T  EL    + A +   +    +V+N+I+EPG  K+I 
Sbjct: 523 LLYETRYEMLATMCGGKGYFVRTEEEL----EAATREGFSNDTVTVVNLIVEPGIGKKIG 578

Query: 552 FAWQ 555
           FAWQ
Sbjct: 579 FAWQ 582
>ref|XP_001591149.1| hypothetical protein SS1G_07774 [Sclerotinia sclerotiorum 1980]
 gb|EDN91913.1| hypothetical protein SS1G_07774 [Sclerotinia sclerotiorum 1980]
          Length = 615

 Score =  395 bits (1014), Expect = e-108,   Method: Composition-based stats.
 Identities = 233/590 (39%), Positives = 338/590 (57%), Gaps = 59/590 (10%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAY 59
           MTT +  Q  A  L+  G++ +FG+VGIP+VQ+A+  +A GI+FI  RNEQAASYAA+AY
Sbjct: 1   MTTYSGAQLIAHTLKDLGVEVIFGLVGIPVVQIAEEAIALGIRFIAFRNEQAASYAATAY 60

Query: 60  GYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSL 119
           GY++ +PGV L+VGGPG++HA+AGI NS +N +P+L++AGSS    + KG FQELD +SL
Sbjct: 61  GYLTGRPGVCLVVGGPGVLHAMAGIGNSSANAFPMLLLAGSSETHLVTKGAFQELDAISL 120

Query: 120 LSPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNEL 179
           L+P  K   + + D I      A      G  G  ++D+PAD I+     EG  R+    
Sbjct: 121 LNPHTKIAIRSSVDTISHSITTAYRTSWYGRPGTGFVDLPADVIQE----EGEYRSTQ-- 174

Query: 180 PMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFL 237
            ++        D   ++K+ +L+     K  L+++GKGA     E  IR L++  N+PFL
Sbjct: 175 -IVTAAPQAAADVEIVEKIARLL--KSAKAPLVIVGKGAAYAQAEVVIRELIDQTNIPFL 231

Query: 238 PTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFD 297
           PTPM KG++PDS P N +++RS ALK AD+VLVLGARLNWILH+G  PK+N +   IQ D
Sbjct: 232 PTPMGKGVLPDSHPSNTATSRSAALKGADVVLVLGARLNWILHYGEVPKYNEDVKIIQVD 291

Query: 298 SNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLN 354
              E +G NN    A+L I GDI +    L++ L      W+Y   S   ++++     N
Sbjct: 292 IAAEEIGRNN--GNAELGIIGDISVVSRQLIDAL----RGWQYDASSAYVKKLKASASKN 345

Query: 355 QTRLLRKEKTRGAQLNYNQVYGTLRPLID------DYRTILVTEGANTMDIARISFPTDA 408
           +    +  K     + Y +V+  ++  I       D   + V+EGANTMDI+R  FP + 
Sbjct: 346 EATAAKFAKVDKIPMTYGRVFDVIKETIHKLSPPRDGGVVYVSEGANTMDISRSVFPVEH 405

Query: 409 PRRRLDAGTNATMGIGLGYALACKASH----PELD---------VVLIQGDSAFGFSAME 455
           PR RLDAGT+ATMG+GLGYA+A   ++    P+           VV ++GDSAFGFS  E
Sbjct: 406 PRLRLDAGTHATMGVGLGYAIAAHCAYNSHLPKAQTGPHSSAKKVVCLEGDSAFGFSLAE 465

Query: 456 IETAVRCQLALVIVVMNNSGIYHGEKD---------------IEGDLPPTALSKNCRYDL 500
           +ET  R  + ++I VMNN G+Y G+ +               I+G L  T+L     Y+ 
Sbjct: 466 VETMARYGMDILIFVMNNGGVYQGDSESSDEWLKLQKNSEGGIKGGLRSTSLGWEVGYEK 525

Query: 501 VGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINVIIEPGEQKQI 550
           V +  G   + V +  ELS+  ++  + S       ++NVIIE G QK +
Sbjct: 526 VAEMCGGKGYLVRSPDELSKATEEGFKAS----APVIVNVIIEAGAQKTL 571
>ref|XP_001244864.1| hypothetical protein CIMG_04305 [Coccidioides immitis RS]
 gb|EAS33281.1| hypothetical protein CIMG_04305 [Coccidioides immitis RS]
          Length = 614

 Score =  390 bits (1002), Expect = e-106,   Method: Composition-based stats.
 Identities = 232/616 (37%), Positives = 342/616 (55%), Gaps = 82/616 (13%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L   G+  +FGIVGIP+V++A+  +  GI+FI  RNEQA SYAASAYGYI+
Sbjct: 5   TGAQLIARSLHDIGVTVIFGIVGIPVVEIAEEAINLGIRFIAFRNEQACSYAASAYGYIT 64

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PG+ L+VGGPG++HA+AGI N+ +N +PL+V+AGS+  + + KGGFQE+D +SLL+P 
Sbjct: 65  GRPGICLVVGGPGVLHAMAGIGNASANAFPLVVLAGSAETTSVTKGGFQEMDAISLLTPH 124

Query: 124 LKFTGKLTPDNIDMI---TQKALNYCIQGTAGVSYIDVPADFIEYEK---PLEGNDRTGN 177
            KF   + P ++  +    + A   C  G  G +++D+PAD I+ +    P   +  T  
Sbjct: 125 TKFA--VRPPSLGAVGGAVRDAYRMCWYGRPGPAFVDLPADLIQAKSTRPPFSVS--TVQ 180

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIR--RLVNTFNLP 235
            LP    P     +P  + KV +++   +    L+VIGKG+     E+   + +    +P
Sbjct: 181 RLP---PPPKSSANPEMVLKVAEILKLARAP--LVVIGKGSAYARAEVSICKFIEQTQIP 235

Query: 236 FLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQ 295
           FLPTPM KG+VPD+  LN SSARS ALK AD+VL+LGARLNWILHFG  P+W+S +  IQ
Sbjct: 236 FLPTPMGKGVVPDTHRLNTSSARSTALKHADVVLLLGARLNWILHFGEEPRWSSSARIIQ 295

Query: 296 FDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY----SGVKQEIREKI 351
            D + E +G N  +  A+L + GD+ L V  L+  L      W+Y    +   Q  +  +
Sbjct: 296 VDIHAEEVGRN--AGDAELGLVGDVDLVVEQLLAALAN----WQYRSPSASPSQSYKSLL 349

Query: 352 QLNQTRLLRKEKTRGAQ-------LNYNQVYGTLRPLIDDYRT------ILVTEGANTMD 398
           +++  +     + +  Q       L + + +  +R + +   +      + V+EGANTMD
Sbjct: 350 KVSSIKNENNSRRQALQRTPANGFLTFQRAFHIIRTVFNSLSSAEEGDIVYVSEGANTMD 409

Query: 399 IARISFPTDAPRRRLDAGTNATMGIGLGYALACKASH----------PELDVVLIQGDSA 448
           I+R  F  + PR+RLDAGT ATMG+GLGY +A  A++           +  +V  +GDSA
Sbjct: 410 ISRSLFQLEHPRQRLDAGTYATMGVGLGYIVAAHAAYNLSSTGENLQKQKKIVAFEGDSA 469

Query: 449 FGFSAMEIETAVRCQLALVIVVMNNSGIYHGEKDIEGD---------------------- 486
           FGFSAMEIET  R Q+  +I VMNNSGIYHG+   E +                      
Sbjct: 470 FGFSAMEIETLARQQIPALIFVMNNSGIYHGDTKTEEEWRKLQKETFTNQIRCSGISNGP 529

Query: 487 -------LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVIN 539
                  L  T+L  N RY+ +    G   FF  T  EL +  ++         +  ++N
Sbjct: 530 SFQTKKGLRSTSLLYNTRYEYLAAMCGGKGFFARTEEELEKATREGFL---ENEKVVIVN 586

Query: 540 VIIEPGEQKQIAFAWQ 555
           VI++PG  + I F WQ
Sbjct: 587 VIVDPGIGQSIQFGWQ 602
>ref|XP_659120.1| hypothetical protein AN1516.2 [Aspergillus nidulans FGSC A4]
 gb|EAA63772.1| hypothetical protein AN1516.2 [Aspergillus nidulans FGSC A4]
          Length = 1279

 Score =  389 bits (1000), Expect = e-106,   Method: Composition-based stats.
 Identities = 239/576 (41%), Positives = 324/576 (56%), Gaps = 65/576 (11%)

Query: 4    TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
            T  Q  A+ L+  G+  +FGIVGIP+V++A+  +  GI+F+  RNEQA SYAAS YGY++
Sbjct: 635  TGAQIIARSLRDLGVTVIFGIVGIPVVEIAEEAINLGIRFVAFRNEQACSYAASVYGYMT 694

Query: 64   DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
             +PGV L+VGGPG++HALAGI NS +N +PLLV+AGS+  S + KG FQELD +SLL+P 
Sbjct: 695  GQPGVCLVVGGPGVLHALAGIGNSSANNFPLLVLAGSAETSAVTKGAFQELDAISLLTPH 754

Query: 124  LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP-- 180
             KF  + +  D I    + A   C  G  G ++ID+PAD I      +G   +  ELP  
Sbjct: 755  TKFAARASSLDFIPDAIKNAYRTCWYGRPGPTFIDLPADII------QGKLTSQFELPKP 808

Query: 181  ---MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLP 235
               ++  P     DP+ I K  QL+        LI++GKGA     E  IR+LV+   +P
Sbjct: 809  ENLLVSAPPKASGDPALILKATQLL--KAASAPLIIVGKGAAYARAELGIRKLVDQTQVP 866

Query: 236  FLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQ 295
            FLPTPM KG+VPDS PLN SSARS ALK AD+VLVLGARLNWILHFG  PKW+ +   IQ
Sbjct: 867  FLPTPMGKGVVPDSHPLNASSARSAALKHADVVLVLGARLNWILHFGEPPKWSPKVKIIQ 926

Query: 296  FDSNPETLGDNNVSPGADLSIWGDIGLSVTAL--VEELTRQDSCWKYSGVKQEIREKIQL 353
             D   E +G N  +  ++L I GDI L V          +  S  K+  +  E  +K + 
Sbjct: 927  VDICAEEIGRN--AGTSELGILGDISLVVDQFRASLSSWKYSSSAKFPLLLAESAKKNED 984

Query: 354  NQTRLLRKEKTRGAQLNYNQVYGTLRPL------IDDYRTILVTEGANTMDIARISFPTD 407
               +   ++   G  L Y + Y  ++        ++D   + V+EGANTMDI+R  FP  
Sbjct: 985  KAQKAALRQTPAGKPLTYQRAYHIIKTALNALTPVEDGNIVYVSEGANTMDISRSIFPLY 1044

Query: 408  APRRRLDAGTNATMGIGLGYALA----------CKASHPELDVVLIQGDSAFGFSAMEIE 457
             PR+RLDAGT ATMG+G+GY +A             S P+  +V  +GDSAFGFSAMEIE
Sbjct: 1045 HPRQRLDAGTYATMGVGMGYIVAAHEAFNANPGASTSRPK-KIVAFEGDSAFGFSAMEIE 1103

Query: 458  TAVRCQLALVIVVMNNSGIYHGE-------------------KDIEGD---------LPP 489
            T  R ++  +I V+NNSGIYHG+                   K  E D         L  
Sbjct: 1104 TLARYRIPALIFVINNSGIYHGDSISKEDWKTLQNQTVANDTKTSESDSGTNAKTKGLRS 1163

Query: 490  TALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQA 525
            T+L    RY+++    G   +FV +  EL R  ++ 
Sbjct: 1164 TSLLYETRYEMLATMCGGKGYFVKSEEELERATKEG 1199
>ref|XP_418737.2| PREDICTED: hypothetical protein [Gallus gallus]
          Length = 568

 Score =  389 bits (998), Expect = e-106,   Method: Composition-based stats.
 Identities = 241/580 (41%), Positives = 335/580 (57%), Gaps = 39/580 (6%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           +  Q  A+ L+   I+ +FG+VGIPI ++A    A GIK+I  RNEQAA YAASA GY++
Sbjct: 5   SGAQLIAEALRAQNIEYMFGVVGIPITEVAVAAQAAGIKYIGMRNEQAACYAASAVGYLT 64

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+V GPG +H L G+ N+  N WPL+VI GSS ++    G FQE  QV     +
Sbjct: 65  GRPGVCLVVSGPGFLHTLGGMANANMNCWPLIVIGGSSDRNQETMGAFQEFPQVEAARLY 124

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
            K + + +  + I  + +KA+   I G  G  YID+P DF+     L+ N  +   +   
Sbjct: 125 NKLSVRPSSLEAIPAVIEKAVRTSIYGRPGSCYIDIPGDFVN----LQVNKSSVKYVECC 180

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTP 240
             P I   + S + + V +I   K    L++IGKGA  +  E  IR+LV+   LPFLPTP
Sbjct: 181 PPPPISTAEHSAVSEAVSIIAHAKQP--LLIIGKGAAYSRAENNIRKLVDLSGLPFLPTP 238

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           MAKG+VPD+ P  V++ARS AL  AD++++LGARLNWILHFG  P++  +   IQ D   
Sbjct: 239 MAKGVVPDNHPNCVAAARSTALLHADVIILLGARLNWILHFGLPPRFRQDVKVIQIDICA 298

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQ---EIREKIQLNQTR 357
           E +G NNV P A L   GDI      L+EE +++    KY    +   ++REK+  N+ R
Sbjct: 299 EEMG-NNVRPAAML--LGDINAVTKQLLEEFSKRP--LKYPSNSEWWKKLREKMLNNEER 353

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  +R L+     ILV+EGANTMDI R   P   PR+RLDAGT
Sbjct: 354 SKDLALQKSLPMNYYTVFHHIRELVPK-DCILVSEGANTMDIGRTMLPNYHPRQRLDAGT 412

Query: 418 NATMGIGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A     K   PE  V+ I+GDSAFGFS ME+ET  R  L ++I+V+NN
Sbjct: 413 FGTMGVGLGFAIAAALVAKDRTPEKRVICIEGDSAFGFSGMEVETICRYNLPILIIVVNN 472

Query: 474 SGIYHG-------EKDIEGD----LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G       E    GD    +PP +L  N  Y+ +    G   +FVNT  EL    
Sbjct: 473 NGIYTGLDAGSWKEMLQYGDPVTSVPPVSLLPNAHYEEIMSAFGGKGYFVNTPEEL---- 528

Query: 523 QQAVQLSRTKRET-SVINVIIEP-GEQKQIAFAWQNKPRL 560
           Q AV+ S   ++T S+INV+I+P  E+K+  F W  +  L
Sbjct: 529 QNAVKASLADKQTPSLINVMIDPQSERKKQEFPWLTRSNL 568
>ref|NP_595484.1| oxalyl-CoA decarboxylase (predicted) [Schizosaccharomyces pombe
           972h-]
 sp|Q9Y7M1|YGK4_SCHPO Putative 2-hydroxyacyl-CoA lyase
 emb|CAA22176.2| oxalyl-CoA decarboxylase (predicted) [Schizosaccharomyces pombe]
          Length = 568

 Score =  386 bits (991), Expect = e-105,   Method: Composition-based stats.
 Identities = 246/588 (41%), Positives = 362/588 (61%), Gaps = 48/588 (8%)

Query: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG 60
           M+ + ++  A+ L    +  VFGIVGIP++++ + + A+GI+F+  RNEQ+A+YAA+AYG
Sbjct: 1   MSISFSELVAKTLLDLEVKVVFGIVGIPVIEICEAIQASGIRFVGFRNEQSAAYAATAYG 60

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
           Y++ +PGV ++VGGPG++HA+AG++NS +NRWPLL++AGSS     + G FQELDQVS L
Sbjct: 61  YLTQRPGVCVVVGGPGVVHAMAGVFNSKTNRWPLLLLAGSSETFQQNCGAFQELDQVSYL 120

Query: 121 SPFLKFTGKLTPDNIDMIT---QKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           SP  K    + P +  M+    ++A    + GT G  Y+D+PA++IE       +D   +
Sbjct: 121 SPHTKLA--VRPPSPKMVVDSIRRAYRVSMTGTPGTCYVDLPANYIESTV----DDFPKD 174

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKN-KNILIVIGKGAVKNSHEIRRL--VNTFNL 234
            LP I +   C PDP++++K    +   KN K  L+V+GKGA     E + L  V    +
Sbjct: 175 PLPPIPSSPKCAPDPTQLQKAAYYL---KNAKAPLLVVGKGAAYACAEKQLLEFVEHTGI 231

Query: 235 PFLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFI 294
           PFLP+PM KG++P+S PLNVSSARS AL+ AD+VL+ GARLNWI  +G  PKW+  + FI
Sbjct: 232 PFLPSPMGKGLLPESHPLNVSSARSAALRNADVVLLAGARLNWIFQYGLPPKWSPNAKFI 291

Query: 295 QFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYS-GVK----QEIRE 349
           Q D+N ETLG+N  +   DL+IW D+GL++  L + +      WKYS G+     + + E
Sbjct: 292 QIDTNAETLGNN--AADLDLAIWADVGLTIDCLFKLV----QTWKYSVGISTPYLRTLNE 345

Query: 350 KIQLNQTRLLRKEKTR-GAQLNY-----NQVYGTLRPLIDDYRTILVTEGANTMDIARIS 403
               N+ + L   K+    Q+NY     N+   +L  L        V+EGANTMD  R  
Sbjct: 346 TRSKNEKKALESRKSSIPLQMNYALYVVNEELQSLS-LKSKRNITWVSEGANTMDRGRQL 404

Query: 404 FPTDAPRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQ 463
                PR RLDAGT +TMG+G+GYA+A   +H    +V+++GDSAFGFSAME+ETA+R Q
Sbjct: 405 LEVTHPRGRLDAGTMSTMGVGMGYAIASAFAHSSDKIVVVEGDSAFGFSAMELETAIRNQ 464

Query: 464 LALVIVVMNNSGIYHG-EKDI------EGDLPPTALSKNCRYDLVGKGLGANDFFVNTIS 516
           L L+++V+NN+G+YHG + D          LP TAL  + RYD + +  G   FFV    
Sbjct: 465 LDLLVIVINNNGVYHGLDTDAYETLRDNHQLPTTALGTSIRYDQICEACGGKGFFVKNEE 524

Query: 517 ELSRCFQQAVQLSRTKRETSVINVIIEPGEQKQIAFAWQN----KPRL 560
           +L    ++A Q S      S+INV+++P   +++ FAW +    KP+L
Sbjct: 525 DLRSSLRKAWQTS----SVSLINVMVDPEAARKLTFAWMSSTKVKPKL 568
>ref|NP_611460.1| CG11208 CG11208-PA [Drosophila melanogaster]
 gb|AAF57501.1| CG11208-PA [Drosophila melanogaster]
 gb|AAL13912.1| LD40177p [Drosophila melanogaster]
          Length = 568

 Score =  385 bits (990), Expect = e-105,   Method: Composition-based stats.
 Identities = 238/586 (40%), Positives = 336/586 (57%), Gaps = 53/586 (9%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISD 64
           A Q  A+ L++ G++ VFGI+GIP+++L+    A G+K+I  RNEQAA YAA A GY++ 
Sbjct: 6   AVQIIAESLKQQGVEYVFGIIGIPVIELSMAFQAAGLKYIGMRNEQAACYAAQAIGYLTG 65

Query: 65  KPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFL 124
           KPGV L+V GPGL+H   G+ N+  N WPL+VI G+++Q     GGFQE  QV L  P+ 
Sbjct: 66  KPGVCLVVSGPGLLHVTGGMANAQVNCWPLIVIGGATNQDHEGIGGFQECPQVELSRPYC 125

Query: 125 KFTGK-LTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMIL 183
           K+  +  T   I +  +KA+ Y   G  GV+Y+D P + ++  K  E +       P   
Sbjct: 126 KYAARPATAALIPLHVEKAVRYATYGRPGVAYLDFPGNILQ-SKAQEASIYKALAHP--- 181

Query: 184 TPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPM 241
            P +  P    + +  +L+ Q K    L+++GKG+     E  +R  +   NLPFLPTPM
Sbjct: 182 APPLAYPPHDDVIRAAKLLRQAKRP--LVIVGKGSAYAHAENTLRHFIENTNLPFLPTPM 239

Query: 242 AKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPE 301
            KG+V D++P  VSSAR+ AL+ AD+VL+LGARLNWILHFG +P+++ +  FIQ D NPE
Sbjct: 240 GKGVVSDTAPQCVSSARTLALQKADVVLLLGARLNWILHFGKAPRYDKDVKFIQVDINPE 299

Query: 302 TLGDNNVSPGADLSIWGDIGLSVTALVEELTR-------QDSCWKYSGVK----QEIREK 350
            L ++ V   A ++I  DI      L E++         +   WK   VK    ++  +K
Sbjct: 300 ELHNSVV---ASVAIQADIRPFAEQLFEQMNAVNFRFGYEQDWWKQLAVKCKQNRDTVQK 356

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           + LN              LNY  V+  LR L+    TI+V+EGANTMDI R     + PR
Sbjct: 357 MSLNTE----------TPLNYYAVFHHLRELLPK-DTIIVSEGANTMDIGRSMLLNEQPR 405

Query: 411 RRLDAGTNATMGIGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLAL 466
            RLDAGT  TMG+G G+A+A    C+   P   V+ ++GDSAFGFS MEIET VR +L +
Sbjct: 406 HRLDAGTFGTMGVGPGFAVAAALFCRDFAPGKRVLCVEGDSAFGFSGMEIETMVRYKLPV 465

Query: 467 VIVVMNNSGIYHG-EKDI------EGDL----PPTALSKNCRYDLVGKGLGANDFFVNTI 515
            IV++NN+GIY G +KD       EGDL    PP+AL    RY+ + K  G   +F   I
Sbjct: 466 TIVIVNNNGIYGGFDKDTFEAIRSEGDLTQITPPSALGVQVRYEEMMKMFGMKGYFCTEI 525

Query: 516 SELSRCFQQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
            +L    + A QL  T R T +INV I P  ++K  +F W  + +L
Sbjct: 526 EQLQAAVKAANQL--TDRPT-IINVAISPSSDRKPQSFNWLTESKL 568
>dbj|BAD72897.1| unnamed protein product [Drosophila simulans]
 dbj|BAD72915.1| unnamed protein product [Drosophila sechellia]
          Length = 568

 Score =  385 bits (989), Expect = e-105,   Method: Composition-based stats.
 Identities = 238/586 (40%), Positives = 335/586 (57%), Gaps = 53/586 (9%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISD 64
           A Q  A+ L++ G++ VFGI+GIP+++L+    A G+K+I  RNEQAA YAA A GY++ 
Sbjct: 6   AVQIIAESLKQQGVEYVFGIIGIPVIELSMAFQAAGLKYIGMRNEQAACYAAQAIGYLTG 65

Query: 65  KPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFL 124
           KPGV L+V GPGL+H   G+ N+  N WPL+VI G+++Q     GGFQE  QV L  P+ 
Sbjct: 66  KPGVCLVVSGPGLLHVTGGMANAQVNCWPLIVIGGATNQDHEGIGGFQECPQVELSRPYC 125

Query: 125 KFTGK-LTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMIL 183
           K+  +  T   I +  +KA+ Y   G  GV+Y+D P + ++  K  E         P   
Sbjct: 126 KYAARPATAALIPLHVEKAVRYATYGRPGVAYLDFPGNILQ-SKAQEARIYKALAHP--- 181

Query: 184 TPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPM 241
            P +  P    + +  +L+ Q K    L+++GKG+     E  +R  +   NLPFLPTPM
Sbjct: 182 APPLAYPPHDDVIRAAKLLRQAKRP--LVIVGKGSAYAHAENTLRHFIENTNLPFLPTPM 239

Query: 242 AKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPE 301
            KG+V D++P  VSSAR+ AL+ AD+VL+LGARLNWILHFG +P+++ +  FIQ D NPE
Sbjct: 240 GKGVVSDTAPQCVSSARTLALQKADVVLLLGARLNWILHFGKAPRYDKDVKFIQVDINPE 299

Query: 302 TLGDNNVSPGADLSIWGDIGLSVTALVEELTR-------QDSCWKYSGVK----QEIREK 350
            L ++ V   A ++I  DI      L E++         +   WK   VK    ++  +K
Sbjct: 300 ELHNSVV---ASVAIQADIRPFAEQLFEQMNAVNFRFGYEQDWWKQLAVKCKQNRDTVQK 356

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           + LN              LNY  V+  LR L+    TI+V+EGANTMDI R     + PR
Sbjct: 357 MSLNTE----------TPLNYYAVFHHLRELLPK-DTIIVSEGANTMDIGRSMLLNEQPR 405

Query: 411 RRLDAGTNATMGIGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLAL 466
            RLDAGT  TMG+G G+A+A    C+   P   V+ ++GDSAFGFS MEIET VR +L +
Sbjct: 406 HRLDAGTFGTMGVGPGFAVAAALFCRDFAPGKRVLCVEGDSAFGFSGMEIETMVRYKLPV 465

Query: 467 VIVVMNNSGIYHG-EKDI------EGDL----PPTALSKNCRYDLVGKGLGANDFFVNTI 515
            IV++NN+GIY G +KD       EGDL    PP+AL    RY+ + K  G   +F   I
Sbjct: 466 TIVIVNNNGIYGGFDKDTFEAIRSEGDLTQITPPSALGVQVRYEEMMKMFGMKGYFCTEI 525

Query: 516 SELSRCFQQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
            +L    + A QL  T R T +INV I P  ++K  +F W  + +L
Sbjct: 526 EQLQAAVKAANQL--TDRPT-IINVAISPSSDRKPQSFNWLTESKL 568
>ref|NP_001017332.1| hypothetical protein LOC550086 [Xenopus tropicalis]
 emb|CAJ81348.1| 2-hydroxyphytanoyl-CoA lyase (hpcl) [Xenopus tropicalis]
          Length = 577

 Score =  383 bits (983), Expect = e-104,   Method: Composition-based stats.
 Identities = 241/581 (41%), Positives = 335/581 (57%), Gaps = 41/581 (7%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L    +  +FGIVGIP++++A    A GIK++  RNEQAA YAASA GY++
Sbjct: 14  TGAQIIAEALVAQNVKYMFGIVGIPVIEIAVAAQAAGIKYVGMRNEQAACYAASAVGYLT 73

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+V GPGLI+AL+G+ NS  N WPL+V+AGSS  +    G FQE  QV     +
Sbjct: 74  GRPGVCLVVSGPGLINALSGMANSNMNCWPLIVLAGSSDTNQETMGAFQEFPQVETSRLY 133

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
            KF+ + +  + I ++ +KA+   I G  G  Y+D+P DF+   K +  +D    E    
Sbjct: 134 SKFSARPSSLEAIPVVIEKAVRSSIYGRPGSCYVDIPGDFV--NKMVNRSDVRYTEC--C 189

Query: 183 LTPNICGPDPSKIKKVVQLILQHKN-KNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPT 239
           L P     DP+ + K V   L+ KN +  L+++GKGA  +  E  I +LV    LPFLPT
Sbjct: 190 LPPPTSLADPTAVHKAV---LELKNAQQPLVIVGKGAAFSRAERSISKLVQDCGLPFLPT 246

Query: 240 PMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSN 299
           PM KG+VPD+ P  V++ARS AL+ AD++L+LGARLNWILHFG  P++  +   IQ D  
Sbjct: 247 PMGKGVVPDNHPNCVAAARSSALQNADVILLLGARLNWILHFGLPPRFRPDVKIIQIDIC 306

Query: 300 PETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQE---IREKIQLNQT 356
            E LG NNV P A  S+ GDI      L+E ++  ++ WKY    +    +R KI+ N+ 
Sbjct: 307 AEELG-NNVKPAA--SLLGDIDAVTQQLLENIS--ETSWKYPASAEWWKILRAKIRSNEE 361

Query: 357 RLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAG 416
                       +NY  V+  ++  +     I+V+EGANTMDI R   P   PR RLDAG
Sbjct: 362 NSKVLASQTSLPMNYYTVFKYVKDALPS-NCIIVSEGANTMDIGRTVLPNYHPRHRLDAG 420

Query: 417 TNATMGIGLGYALAC----KASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMN 472
           T  TMG+GLG+A+A     K   PE  VV I+GDSAFGFS ME ET  R +L ++I+V+N
Sbjct: 421 TFGTMGVGLGFAIAAAMITKDECPEQRVVCIEGDSAFGFSGMEAETMCRYKLPIIIIVVN 480

Query: 473 NSGIYHG-------EKDIEGD----LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRC 521
           N+GIY+G       E    GD     PP AL  N  Y+ V K  G   +F  T  EL   
Sbjct: 481 NNGIYNGFDEGTWNEMMESGDPATMAPPVALMPNAHYEQVMKAFGGKGYFARTPEEL--- 537

Query: 522 FQQAVQLSRTKRET-SVINVIIEP-GEQKQIAFAWQNKPRL 560
            Q A++ S  ++   S+INV+I+P  ++K+  F W  +  L
Sbjct: 538 -QNALKSSFAEKAVPSLINVMIDPVSDRKKQEFHWLTRSNL 577
>ref|XP_001361932.1| GA10842-PA [Drosophila pseudoobscura]
 gb|EAL26511.1| GA10842-PA [Drosophila pseudoobscura]
          Length = 568

 Score =  381 bits (979), Expect = e-104,   Method: Composition-based stats.
 Identities = 233/576 (40%), Positives = 333/576 (57%), Gaps = 33/576 (5%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISD 64
           A Q  A+ L++ G+D VFGI+GIP+++L+    A G+K+I  RNEQ+A YAA A GY++ 
Sbjct: 6   AVQIIAESLKQQGVDYVFGIIGIPVIELSMAFQAAGLKYIGMRNEQSACYAAQAIGYLTG 65

Query: 65  KPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFL 124
           KPGV L+V GPGL+H   G+ N+  N WPL+VI G+++Q     GGFQE  QV L  P+ 
Sbjct: 66  KPGVCLVVSGPGLLHVTGGMANAQVNCWPLIVIGGATNQDHEGIGGFQECPQVELSRPYC 125

Query: 125 KFTGK-LTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMIL 183
           K+  +  T   I +  +KA+ Y   G  GV+Y+D P + ++ + P E         P   
Sbjct: 126 KYAARPPTAALIPLHVEKAVRYATYGRPGVAYLDFPGNILQSKAP-EARIYKALAHP--- 181

Query: 184 TPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPM 241
            P +  P    +    +L+ Q K    L+++GKG      E  +R  +   NLPFLPTPM
Sbjct: 182 APPVAYPPHDDVIAASRLLRQAKRP--LVIVGKGCAYAHAENTLRHFIENTNLPFLPTPM 239

Query: 242 AKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPE 301
            KG+V D++P  VSSAR+ AL+ AD+VL+LGARLNWILHFG SP+++ +  FIQ D  PE
Sbjct: 240 GKGVVSDTAPQCVSSARTLALQKADVVLLLGARLNWILHFGRSPRYDKDVKFIQVDICPE 299

Query: 302 TLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY-SGVKQEIREKIQLNQTRLLR 360
            L ++ +S    ++I  DI      L E++   +  + Y     +++  K + N+  + +
Sbjct: 300 ELHNSVIS---SVAIQSDIRPFAEQLFEQMNAVNFRFGYEQDWWKQLAVKCKQNKDTVQQ 356

Query: 361 KEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT 420
                   LNY  V+  LR L+    TI+V+EGANTMDI R     + PR RLDAGT  T
Sbjct: 357 MSLNTSTPLNYYAVFHHLRELLPK-DTIIVSEGANTMDIGRSMLLNEQPRHRLDAGTFGT 415

Query: 421 MGIGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGI 476
           MG+G G+A+A    C+   P   V+ ++GDSAFGFS MEIET VR +L + IV++NN+GI
Sbjct: 416 MGVGPGFAVAAALFCRDFAPGKRVLCVEGDSAFGFSGMEIETMVRYKLPVTIVIVNNNGI 475

Query: 477 YHG-EKDI------EGDL----PPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQA 525
           Y G +KD       EGDL    PP+AL    RY+ + K  G   +F   I +L    + A
Sbjct: 476 YGGFDKDTFEAIRSEGDLTQITPPSALGVQVRYEEMMKMFGMQGYFCTEIEQLQTAIKAA 535

Query: 526 VQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
            QL  T R T +INV I P  ++K  +F W  + +L
Sbjct: 536 NQL--TDRPT-IINVAISPSSDRKPQSFNWLTESKL 568
>emb|CAB60200.1| 2-hydroxyphytanoyl-CoA lyase [Homo sapiens]
          Length = 578

 Score =  381 bits (978), Expect = e-104,   Method: Composition-based stats.
 Identities = 228/574 (39%), Positives = 326/574 (56%), Gaps = 39/574 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV 
Sbjct: 21  AQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVC 80

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV     + KF+ +
Sbjct: 81  LVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSAR 140

Query: 130 LTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNIC 188
            +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   +   ++P I 
Sbjct: 141 XSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMERCMSPPIS 196

Query: 189 GPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKGIV 246
             + S +     +I     K  L++IGKGA     E  I++LV  + LPFLPTPM KG+V
Sbjct: 197 MAETSAVCTAASVI--RNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVV 254

Query: 247 PDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDN 306
           PD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   E LG N
Sbjct: 255 PDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELG-N 313

Query: 307 NVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEK 363
           NV P   +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+        
Sbjct: 314 NVKPA--VTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAASKELAS 369

Query: 364 TRGAQLNYNQV-YGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMG 422
            +   +NY  V Y     L  D    +V+EGANTMDI R       PR RLDAGT  TMG
Sbjct: 370 KKSLPMNYYTVFYHVQEQLPRD--CFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMG 427

Query: 423 IGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYH 478
           +GLG+A+A     K   P   ++ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY 
Sbjct: 428 VGLGFAIAAAVVAKDRSPGHWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQ 487

Query: 479 G-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           G            +D    +PP  L  N  Y+ V    G   +FV T  EL +  +Q+  
Sbjct: 488 GFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLEQS-- 545

Query: 528 LSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           L+ T +  S+IN++IEP   +K   F W  +  +
Sbjct: 546 LADTTK-PSLINIMIEPQATRKAQDFHWLTRSNM 578
>ref|NP_001086822.1| MGC82654 protein [Xenopus laevis]
 gb|AAH77507.1| MGC82654 protein [Xenopus laevis]
          Length = 577

 Score =  380 bits (977), Expect = e-103,   Method: Composition-based stats.
 Identities = 240/581 (41%), Positives = 333/581 (57%), Gaps = 41/581 (7%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L    +  +FGIVGIP++++A    A GIK++  RNEQAA YAASA GY++
Sbjct: 14  TGAQIIAEALVAQNVKYMFGIVGIPVIEIAVAAQAAGIKYVGMRNEQAACYAASAVGYLT 73

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+V GPGLI+AL+G+ NS  N WPL+V+AGSS  +    G FQE  QV     +
Sbjct: 74  GRPGVCLVVSGPGLINALSGMANSNMNCWPLIVLAGSSDTNQETMGAFQEFPQVETCRLY 133

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
            KF+ + +  + I ++ +KA+   I G  G  Y+D+P DF+   K +  +D    E    
Sbjct: 134 SKFSARPSSLEAIPVVIEKAVRSSIYGRPGSCYVDIPGDFV--NKMVNRSDVRYTEC--C 189

Query: 183 LTPNICGPDPSKIKKVVQLILQHKN-KNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPT 239
           L P     DP+ + K V L+   KN +  LI++GKGA  +  E  IR+LV  + LPFLPT
Sbjct: 190 LPPPTSLADPTTVNKAVSLL---KNAQQPLIIVGKGAAFSHAEKSIRKLVQDYGLPFLPT 246

Query: 240 PMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSN 299
           PM KG+VPD+ P  V++ARS AL+ AD++L+LGARLNWILHFG  P++  +   IQ D  
Sbjct: 247 PMGKGVVPDNHPNCVAAARSSALQNADVILLLGARLNWILHFGLPPRFRPDVKIIQVDIC 306

Query: 300 PETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQ---EIREKIQLNQT 356
            E LG NNV P A  S+ GDI      L+E L +  + WKY    +    +  KI+ N+ 
Sbjct: 307 AEELG-NNVKPAA--SLLGDIDAVTQQLLEHLGK--TSWKYPANTEWWKTLMTKIRANEE 361

Query: 357 RLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAG 416
                       +NY  V+  ++  + +   I+V+EGANTMDI R       PR RLDAG
Sbjct: 362 NSKVLASQTSLPMNYYTVFQYVKESLPN-NCIIVSEGANTMDIGRTILQNYHPRHRLDAG 420

Query: 417 TNATMGIGLGYALAC----KASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMN 472
           T  TMG+GLG+A+A     K   PE  VV ++GDSAFGFS ME ET  R  L ++I+V+N
Sbjct: 421 TFGTMGVGLGFAIAAAMITKDECPEQRVVCVEGDSAFGFSGMEAETMCRYNLPIIIIVVN 480

Query: 473 NSGIYHG-------EKDIEGD----LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRC 521
           N+GIY+G       E    GD     PP AL  N  Y+ V    G   +F  T  EL   
Sbjct: 481 NNGIYNGFDEGTWNEMIKSGDPATIAPPVALMPNAHYEQVMMAFGGKGYFARTPEEL--- 537

Query: 522 FQQAVQLSRTKRE-TSVINVIIEP-GEQKQIAFAWQNKPRL 560
            Q A++ S  ++   S+INV+I+P  ++K+  F W  +  L
Sbjct: 538 -QNALRASFAEKNGPSLINVMIDPVSDRKKQDFHWLTRSNL 577
>gb|AAF28957.1|AF161397_1 HSPC279 [Homo sapiens]
          Length = 581

 Score =  380 bits (975), Expect = e-103,   Method: Composition-based stats.
 Identities = 228/574 (39%), Positives = 326/574 (56%), Gaps = 39/574 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV 
Sbjct: 24  AQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVC 83

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV     + KF+ +
Sbjct: 84  LVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSAR 143

Query: 130 LTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNIC 188
            +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   +   ++P I 
Sbjct: 144 PSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMERCMSPPIS 199

Query: 189 GPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKGIV 246
             + S +     +I     K  L++IGKGA     E  I++LV  + LPFLPTPM KG+V
Sbjct: 200 MAETSAVCTAASVI--RNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVV 257

Query: 247 PDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDN 306
           PD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   E LG N
Sbjct: 258 PDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELG-N 316

Query: 307 NVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEK 363
           NV P   +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+        
Sbjct: 317 NVKPA--VTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAASKELAS 372

Query: 364 TRGAQLNYNQV-YGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMG 422
            +   +NY  V Y     L  D    +V+EGANTMDI R       PR RLDAGT  TMG
Sbjct: 373 KKSLPMNYYTVFYHVQEQLPRD--CFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMG 430

Query: 423 IGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYH 478
           +GLG+A+A     K   P   ++ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY 
Sbjct: 431 VGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQ 490

Query: 479 G-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           G            +D    +PP  L  N  Y+ V    G   +FV T  EL +  +Q+  
Sbjct: 491 GFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQS-- 548

Query: 528 LSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           L+ T +  S+IN++IEP   +K   F W  +  +
Sbjct: 549 LADTTK-PSLINIMIEPQATRKAQDFHWLTRSNM 581
>ref|XP_001864201.1| 2-hydroxyacyl-CoA lyase 1 [Culex pipiens quinquefasciatus]
 gb|EDS39871.1| 2-hydroxyacyl-CoA lyase 1 [Culex pipiens quinquefasciatus]
          Length = 567

 Score =  379 bits (974), Expect = e-103,   Method: Composition-based stats.
 Identities = 234/583 (40%), Positives = 331/583 (56%), Gaps = 55/583 (9%)

Query: 9   FAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGV 68
            A+ L++ G++ VFGIVGIP+++L+  M A G+K+I  RNEQ+A YAA A GY++ KPGV
Sbjct: 9   LARSLKEQGVEYVFGIVGIPVIELSMAMQAEGLKYIGMRNEQSACYAAQAIGYLTGKPGV 68

Query: 69  LLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTG 128
            L+V GPGL+H   G+ N+  N WPLLVI GS+ Q     GGFQE  QV L  P+ K++ 
Sbjct: 69  CLVVSGPGLLHVTGGMANAQVNCWPLLVIGGSTFQDHEGIGGFQECPQVELSRPYCKYSA 128

Query: 129 KLTPDNIDMITQ---KALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILT- 184
           +  P  + +I Q   KA+     G  G +Y+D P + +    P E       ++P     
Sbjct: 129 R--PAGVTLIPQHVEKAVRLACYGRPGAAYLDFPGNLLLARVPEE-------KVPKQYAH 179

Query: 185 --PNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTP 240
             P I  P    +++   L+   K    LI+IGKGA     E  +R+LV+  NLPFLPTP
Sbjct: 180 PEPPIAFPSEKCVRQAAHLLANAKRP--LIIIGKGAAYARAELHLRQLVHQTNLPFLPTP 237

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD  P  V+ AR+ AL+ AD +L+LGARLNW+LHFG +P+++     IQ D NP
Sbjct: 238 MGKGVVPDLDPQCVAPARTLALQKADCILLLGARLNWMLHFGRAPRYSEGVKIIQVDLNP 297

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELT-------RQDSCWKYSGVKQEIREKIQL 353
           E L ++ +S    +++  DI      L++EL         ++  W       ++R K   
Sbjct: 298 EELHNSVLS---SVAVQSDIVPFTEQLIDELANMHFTFDNKNDWW------VDLRAKCDK 348

Query: 354 NQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRL 413
           N+  + +  +     LNY+ V+  L+ LI     I+V+EGANTMDI R       PR RL
Sbjct: 349 NRKIVDKMAQDVKVPLNYHAVFHHLQELIPK-DAIIVSEGANTMDIGRTFLHNKWPRHRL 407

Query: 414 DAGTNATMGIGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIV 469
           DAGT  TMG+G G+A+A    C+   P   V+ ++GDSAFGFS MEIET +R QL +VIV
Sbjct: 408 DAGTFGTMGVGPGFAIAAALVCRDRFPGEKVICVEGDSAFGFSGMEIETMMRYQLPVVIV 467

Query: 470 VMNNSGIYHG-EKDIEGDL----------PPTALSKNCRYDLVGKGLGANDFFVNTISEL 518
           ++NN GIY G +K    D+          PPTAL+    Y+ +    GA   FV TI EL
Sbjct: 468 IVNNGGIYSGFDKQTYDDMRSGGDLTQVTPPTALAVETHYEAMMGMFGATGHFVRTIPEL 527

Query: 519 SRCFQQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
            +  ++A+ L  T R T +INVII P  ++K   F W  + +L
Sbjct: 528 QKAVKEALVL--TDRPT-IINVIISPQADRKPQDFQWLTESKL 567
>ref|NP_036392.2| 2-hydroxyphytanoyl-CoA lyase [Homo sapiens]
 sp|Q9UJ83|HACL1_HUMAN 2-hydroxyacyl-CoA lyase 1 (2-hydroxyphytanoyl-CoA lyase) (2-HPCL)
           (Phytanoyl-CoA 2-hydroxylase 2)
 gb|AAH01627.1| 2-hydroxyacyl-CoA lyase 1 [Homo sapiens]
 gb|EAW64251.1| phytanoyl-CoA 2-hydroxylase 2, isoform CRA_a [Homo sapiens]
 gb|ABM86484.1| 2-hydroxyacyl-CoA lyase 1 [synthetic construct]
 gb|ABW03818.1| 2-hydroxyacyl-CoA lyase 1 [synthetic construct]
          Length = 578

 Score =  379 bits (974), Expect = e-103,   Method: Composition-based stats.
 Identities = 228/574 (39%), Positives = 326/574 (56%), Gaps = 39/574 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV 
Sbjct: 21  AQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVC 80

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV     + KF+ +
Sbjct: 81  LVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSAR 140

Query: 130 LTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNIC 188
            +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   +   ++P I 
Sbjct: 141 PSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMERCMSPPIS 196

Query: 189 GPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKGIV 246
             + S +     +I     K  L++IGKGA     E  I++LV  + LPFLPTPM KG+V
Sbjct: 197 MAETSAVCTAASVI--RNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVV 254

Query: 247 PDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDN 306
           PD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   E LG N
Sbjct: 255 PDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELG-N 313

Query: 307 NVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEK 363
           NV P   +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+        
Sbjct: 314 NVKPA--VTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAASKELAS 369

Query: 364 TRGAQLNYNQV-YGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMG 422
            +   +NY  V Y     L  D    +V+EGANTMDI R       PR RLDAGT  TMG
Sbjct: 370 KKSLPMNYYTVFYHVQEQLPRD--CFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMG 427

Query: 423 IGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYH 478
           +GLG+A+A     K   P   ++ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY 
Sbjct: 428 VGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQ 487

Query: 479 G-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           G            +D    +PP  L  N  Y+ V    G   +FV T  EL +  +Q+  
Sbjct: 488 GFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQS-- 545

Query: 528 LSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           L+ T +  S+IN++IEP   +K   F W  +  +
Sbjct: 546 LADTTK-PSLINIMIEPQATRKAQDFHWLTRSNM 578
>ref|XP_001160528.1| PREDICTED: 2-hydroxyphytanoyl-CoA lyase isoform 8 [Pan troglodytes]
          Length = 578

 Score =  379 bits (974), Expect = e-103,   Method: Composition-based stats.
 Identities = 226/573 (39%), Positives = 327/573 (57%), Gaps = 37/573 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV 
Sbjct: 21  AQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVC 80

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV     + KF+ +
Sbjct: 81  LVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSAR 140

Query: 130 LTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNIC 188
            +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   +   ++P I 
Sbjct: 141 PSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMERCMSPPIS 196

Query: 189 GPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKGIV 246
             + S +     +I     K  L++IGKGA     E  I++LV  + LPFLPTPM KG+V
Sbjct: 197 MAETSAVCTAASVI--RNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVV 254

Query: 247 PDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDN 306
           PD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   E LG N
Sbjct: 255 PDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELG-N 313

Query: 307 NVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEK 363
           NV P   +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+        
Sbjct: 314 NVKP--TVTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAASKELAS 369

Query: 364 TRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGI 423
            +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT  TMG+
Sbjct: 370 KKSLPMNYYTVFYHIQEQLPR-DCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGV 428

Query: 424 GLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHG 479
           GLG+A+A     K   P   ++ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY G
Sbjct: 429 GLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQG 488

Query: 480 -----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQL 528
                       +D    +PP  L  N  Y+ V    G   +FV T  EL +  +Q+  L
Sbjct: 489 FDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQS--L 546

Query: 529 SRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           + T +  S+INV+IEP   +K   F W  +  +
Sbjct: 547 ADTTK-PSLINVMIEPQATRKAQDFHWLTRSNM 578
>ref|XP_001868099.1| 2-hydroxyphytanoyl-coa lyase [Culex pipiens quinquefasciatus]
 gb|EDS26088.1| 2-hydroxyphytanoyl-coa lyase [Culex pipiens quinquefasciatus]
          Length = 567

 Score =  379 bits (973), Expect = e-103,   Method: Composition-based stats.
 Identities = 233/583 (39%), Positives = 331/583 (56%), Gaps = 55/583 (9%)

Query: 9   FAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGV 68
            A+ L++ G++ VFGIVGIP+++L+  M A G+K+I  RNEQ+A YAA A GY++ KPG+
Sbjct: 9   LARSLKEQGVEYVFGIVGIPVIELSMAMQAEGLKYIGMRNEQSACYAAQAIGYLTGKPGI 68

Query: 69  LLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTG 128
            L+V GPGL+H   G+ N+  N WPLLVI GS+ Q     GGFQE  QV L  P+ K++ 
Sbjct: 69  CLVVSGPGLLHVTGGMANAQVNCWPLLVIGGSTFQDHEGIGGFQECPQVELSRPYCKYSA 128

Query: 129 KLTPDNIDMITQ---KALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILT- 184
           +  P  + +I Q   KA+     G  G +Y+D P + +    P E       ++P     
Sbjct: 129 R--PAGVTLIPQHVEKAVRLACYGRPGAAYLDFPGNLLLARVPEE-------KVPKQYAH 179

Query: 185 --PNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTP 240
             P I  P    +++   L+   K    LI+IGKGA     E  +R+LV+  NLPFLPTP
Sbjct: 180 PEPPIAFPSEKCVRQAAHLLANAKRP--LIIIGKGAAYARAELHLRQLVHQTNLPFLPTP 237

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD  P  V+ AR+ AL+ AD +L+LGARLNW+LHFG +P+++     IQ D NP
Sbjct: 238 MGKGVVPDLDPQCVAPARTLALQKADCILLLGARLNWMLHFGRAPRYSEGVKIIQVDLNP 297

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELT-------RQDSCWKYSGVKQEIREKIQL 353
           E L ++ +S    +++  DI      L++EL         ++  W       ++R K   
Sbjct: 298 EELHNSVLS---SVAVQSDIVPFTEQLIDELANMHFTFDNKNDWW------VDLRAKCDK 348

Query: 354 NQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRL 413
           N+  + +  +     LNY+ V+  L+ LI     I+V+EGANTMDI R       PR RL
Sbjct: 349 NRKIVDKMAQDVKVPLNYHAVFHHLQELIPK-DAIIVSEGANTMDIGRTFLHNKWPRHRL 407

Query: 414 DAGTNATMGIGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIV 469
           DAGT  TMG+G G+A+A    C+   P   V+ ++GDSAFGFS MEIET +R QL +VIV
Sbjct: 408 DAGTFGTMGVGPGFAIAAALVCRDRFPGEKVICVEGDSAFGFSGMEIETMMRYQLPVVIV 467

Query: 470 VMNNSGIYHG-EKDIEGDL----------PPTALSKNCRYDLVGKGLGANDFFVNTISEL 518
           ++NN GIY G +K    D+          PPTAL+    Y+ +    GA   FV TI EL
Sbjct: 468 IVNNGGIYSGFDKQTYDDMRSGGDLTQVTPPTALAVETHYEAMMGMFGATGHFVRTIPEL 527

Query: 519 SRCFQQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
            +  ++A+ L  T R T +INVII P  ++K   F W  + +L
Sbjct: 528 QKAVKEALVL--TDRPT-IINVIISPQADRKPQDFQWLTESKL 567
>ref|XP_001160421.1| PREDICTED: 2-hydroxyphytanoyl-CoA lyase isoform 6 [Pan troglodytes]
          Length = 632

 Score =  379 bits (972), Expect = e-103,   Method: Composition-based stats.
 Identities = 223/561 (39%), Positives = 323/561 (57%), Gaps = 36/561 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV 
Sbjct: 21  AQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVC 80

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV     + KF+ +
Sbjct: 81  LVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSAR 140

Query: 130 LTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNIC 188
            +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   +   ++P I 
Sbjct: 141 PSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMERCMSPPIS 196

Query: 189 GPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKGIV 246
             + S +     +I     K  L++IGKGA     E  I++LV  + LPFLPTPM KG+V
Sbjct: 197 MAETSAVCTAASVI--RNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVV 254

Query: 247 PDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDN 306
           PD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   E LG N
Sbjct: 255 PDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELG-N 313

Query: 307 NVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEK 363
           NV P   +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+        
Sbjct: 314 NVKP--TVTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAASKELAS 369

Query: 364 TRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGI 423
            +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT  TMG+
Sbjct: 370 KKSLPMNYYTVFYHIQEQLPR-DCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGV 428

Query: 424 GLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHG 479
           GLG+A+A     K   P   ++ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY G
Sbjct: 429 GLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQG 488

Query: 480 -----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQL 528
                       +D    +PP  L  N  Y+ V    G   +FV T  EL +  +Q+  L
Sbjct: 489 FDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQS--L 546

Query: 529 SRTKRETSVINVIIEPGEQKQ 549
           + T +  S+INV+IEP   ++
Sbjct: 547 ADTTK-PSLINVMIEPQATRK 566
>ref|XP_001160179.1| PREDICTED: 2-hydroxyphytanoyl-CoA lyase isoform 1 [Pan troglodytes]
          Length = 557

 Score =  377 bits (968), Expect = e-102,   Method: Composition-based stats.
 Identities = 223/565 (39%), Positives = 323/565 (57%), Gaps = 37/565 (6%)

Query: 18  IDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVLLIVGGPGL 77
           ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV L+V GPGL
Sbjct: 8   VEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVCLVVSGPGL 67

Query: 78  IHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGKLTP-DNID 136
           IHAL G+ N+  N WPLLVI GSS ++    G FQE  QV     + KF+ + +  + I 
Sbjct: 68  IHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIP 127

Query: 137 MITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNICGPDPSKIK 196
            + +KA+   I G  G  Y+D+PADF+     L+ N  +   +   ++P I   + S + 
Sbjct: 128 FVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMERCMSPPISMAETSAVC 183

Query: 197 KVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKGIVPDSSPLNV 254
               +I     K  L++IGKGA     E  I++LV  + LPFLPTPM KG+VPD+ P  V
Sbjct: 184 TAASVI--RNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCV 241

Query: 255 SSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDNNVSPGADL 314
            +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   E LG NNV P   +
Sbjct: 242 GAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELG-NNVKP--TV 298

Query: 315 SIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEKTRGAQLNY 371
           ++ G+I      L+EEL +  + W+Y   S   + +REK++ N+         +   +NY
Sbjct: 299 TLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNY 356

Query: 372 NQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGIGLGYALA- 430
             V+  ++  +      +V+EGANTMDI R       PR RLDAGT  TMG+GLG+A+A 
Sbjct: 357 YTVFYHIQEQLPR-DCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAA 415

Query: 431 ---CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHG-------- 479
               K   P   ++ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY G        
Sbjct: 416 AVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQGFDTDTWKE 475

Query: 480 ---EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETS 536
               +D    +PP  L  N  Y+ V    G   +FV T  EL +  +Q+  L+ T +  S
Sbjct: 476 MLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQS--LADTTK-PS 532

Query: 537 VINVIIEP-GEQKQIAFAWQNKPRL 560
           +INV+IEP   +K   F W  +  +
Sbjct: 533 LINVMIEPQATRKAQDFHWLTRSNM 557
>ref|XP_001160475.1| PREDICTED: 2-hydroxyphytanoyl-CoA lyase isoform 7 [Pan troglodytes]
          Length = 628

 Score =  377 bits (968), Expect = e-102,   Method: Composition-based stats.
 Identities = 223/561 (39%), Positives = 323/561 (57%), Gaps = 36/561 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV 
Sbjct: 21  AQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVC 80

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV     + KF+ +
Sbjct: 81  LVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSAR 140

Query: 130 LTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNIC 188
            +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   +   ++P I 
Sbjct: 141 PSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMERCMSPPIS 196

Query: 189 GPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKGIV 246
             + S +     +I     K  L++IGKGA     E  I++LV  + LPFLPTPM KG+V
Sbjct: 197 MAETSAVCTAASVI--RNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVV 254

Query: 247 PDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDN 306
           PD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   E LG N
Sbjct: 255 PDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELG-N 313

Query: 307 NVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEK 363
           NV P   +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+        
Sbjct: 314 NVKP--TVTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAASKELAS 369

Query: 364 TRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGI 423
            +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT  TMG+
Sbjct: 370 KKSLPMNYYTVFYHIQEQLPR-DCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGV 428

Query: 424 GLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHG 479
           GLG+A+A     K   P   ++ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY G
Sbjct: 429 GLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQG 488

Query: 480 -----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQL 528
                       +D    +PP  L  N  Y+ V    G   +FV T  EL +  +Q+  L
Sbjct: 489 FDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQS--L 546

Query: 529 SRTKRETSVINVIIEPGEQKQ 549
           + T +  S+INV+IEP   ++
Sbjct: 547 ADTTK-PSLINVMIEPQATRK 566
>ref|XP_001160323.1| PREDICTED: 2-hydroxyphytanoyl-CoA lyase isoform 4 [Pan troglodytes]
          Length = 566

 Score =  376 bits (965), Expect = e-102,   Method: Composition-based stats.
 Identities = 223/565 (39%), Positives = 323/565 (57%), Gaps = 37/565 (6%)

Query: 18  IDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVLLIVGGPGL 77
           ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV L+V GPGL
Sbjct: 17  VEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVCLVVSGPGL 76

Query: 78  IHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGKLTP-DNID 136
           IHAL G+ N+  N WPLLVI GSS ++    G FQE  QV     + KF+ + +  + I 
Sbjct: 77  IHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAIP 136

Query: 137 MITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNICGPDPSKIK 196
            + +KA+   I G  G  Y+D+PADF+     L+ N  +   +   ++P I   + S + 
Sbjct: 137 FVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMERCMSPPISMAETSAVC 192

Query: 197 KVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKGIVPDSSPLNV 254
               +I     K  L++IGKGA     E  I++LV  + LPFLPTPM KG+VPD+ P  V
Sbjct: 193 TAASVI--RNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCV 250

Query: 255 SSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDNNVSPGADL 314
            +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   E LG NNV P   +
Sbjct: 251 GAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELG-NNVKP--TV 307

Query: 315 SIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEKTRGAQLNY 371
           ++ G+I      L+EEL +  + W+Y   S   + +REK++ N+         +   +NY
Sbjct: 308 TLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNY 365

Query: 372 NQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGIGLGYALA- 430
             V+  ++  +      +V+EGANTMDI R       PR RLDAGT  TMG+GLG+A+A 
Sbjct: 366 YTVFYHIQEQLPR-DCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAA 424

Query: 431 ---CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHG-------- 479
               K   P   ++ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY G        
Sbjct: 425 AVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQGFDTDTWKE 484

Query: 480 ---EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETS 536
               +D    +PP  L  N  Y+ V    G   +FV T  EL +  +Q+  L+ T +  S
Sbjct: 485 MLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQS--LADTTK-PS 541

Query: 537 VINVIIEP-GEQKQIAFAWQNKPRL 560
           +INV+IEP   +K   F W  +  +
Sbjct: 542 LINVMIEPQATRKAQDFHWLTRSNM 566
>ref|XP_534256.2| PREDICTED: similar to 2-hydroxyphytanoyl-CoA lyase (2-HPCL) [Canis
           familiaris]
          Length = 667

 Score =  375 bits (963), Expect = e-102,   Method: Composition-based stats.
 Identities = 227/579 (39%), Positives = 328/579 (56%), Gaps = 37/579 (6%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           +  +  AQ L+   ++ VFGIVGIP+ ++A      GI+++  RNEQAA YAASA GY++
Sbjct: 104 SGAEVIAQALKTQDVEYVFGIVGIPVTEIAVAAQKLGIRYVGMRNEQAACYAASAVGYLT 163

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+V GPGLIHAL G+ N+  N WPL+VI GSS +     G FQE  QV     +
Sbjct: 164 GRPGVCLVVSGPGLIHALGGMANANVNCWPLIVIGGSSERRQETMGAFQEFPQVEACRLY 223

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
            KF+ + +  + I  I +KA+   I G  G  Y+D+PADF+ ++     N  +   +   
Sbjct: 224 CKFSARPSSIETIPSIIEKAVRSSIYGRPGPCYVDIPADFVNFQV----NVNSIKYVECC 279

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTP 240
           L P +   + S +     ++     K  L++IGKGA  +  E  IR+LV    LPFLPTP
Sbjct: 280 LPPPVSMAETSAVYMAASVL--RNAKRPLLIIGKGAAYSRAEEAIRKLVGQCKLPFLPTP 337

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD+ P  VS+ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   
Sbjct: 338 MGKGVVPDNHPNCVSAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQIDICA 397

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTR 357
           E LG NNV P   +S+ GDI      L+E+  +  + W+Y   S   Q +REK++ N+  
Sbjct: 398 EELG-NNVKPA--VSLLGDINAVTKQLLEQFDK--TPWQYPPESSWWQTLREKMESNEAA 452

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT
Sbjct: 453 SKELASQKSLPMNYYTVFYQVQEQLPR-DCFVVSEGANTMDIGRTVIQNYLPRHRLDAGT 511

Query: 418 NATMGIGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A     +  +P   V+ ++GDSAFGFS ME+ET  R  L +V++V+NN
Sbjct: 512 FGTMGVGLGFAIAAAIVARDRNPGKRVICVEGDSAFGFSGMEVETICRYNLPIVLLVVNN 571

Query: 474 SGIYHG-------EKDIEGD----LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G       E    GD     PP  L  N  Y+ V    G   +FV T  EL +  
Sbjct: 572 NGIYQGFDADSWKEMLKFGDATEVAPPVCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSL 631

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           +++  L+ T +  S+IN++IEP   +K   F W  +  +
Sbjct: 632 RES--LADTTK-PSLINIMIEPQATRKAQDFHWLTRSNM 667
>ref|XP_975143.1| PREDICTED: similar to CG11208-PA [Tribolium castaneum]
          Length = 568

 Score =  374 bits (960), Expect = e-101,   Method: Composition-based stats.
 Identities = 227/576 (39%), Positives = 333/576 (57%), Gaps = 41/576 (7%)

Query: 9   FAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGV 68
            AQ L++ GI+ VFGI G P+++L+  +   GI +I  RNEQAA YAA A GY++  PG 
Sbjct: 10  LAQALKEQGIEYVFGICGFPVIELSMALQTAGIHYIGMRNEQAACYAAQAIGYLTGVPGG 69

Query: 69  LLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTG 128
           +L+V GPGL+H  AG+ N+  N WP++VI GS  Q     GGFQE  QV L  P+ K++ 
Sbjct: 70  VLVVSGPGLLHVCAGMANAQVNCWPVVVIGGSCPQDHEGIGGFQECYQVELARPYCKYSA 129

Query: 129 KLTPDNIDMITQ---KALNYCIQGTAGVSYIDVPADFIEYEKPLEG--NDRTGNELPMIL 183
           +  P ++ +I Q   KA+     G  G  Y+D P + ++    ++      T  E+P+I 
Sbjct: 130 R--PPSLALIPQHVEKAVRLATYGRPGAVYLDFPGNLLQARTTIDKIPKQYTAPEIPVIY 187

Query: 184 TPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGA--VKNSHEIRRLVNTFNLPFLPTPM 241
                 P+P KI +   LI+  +    L+++GKGA   +   ++R LV++ NLPFL TPM
Sbjct: 188 ------PEPRKIDEAAALIMGAQRP--LVIVGKGAAYARAEGQVRELVDSTNLPFLATPM 239

Query: 242 AKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPE 301
            KG+V D++P ++  ARS AL+ AD+VL+LGARLNWILHFG  P++N     IQ D   E
Sbjct: 240 GKGVVSDTNPNSIQPARSLALQRADVVLLLGARLNWILHFGRPPRYNPNVKVIQIDVCAE 299

Query: 302 TLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCW-KYSGVKQEIREKIQLNQTRLLR 360
            L   N S  A ++I  D+  +V  LV+ L R++  + K S    ++ +KIQ N+ ++  
Sbjct: 300 EL---NNSVKAAVAIQSDLKPAVGQLVQSLKRRNFTFSKNSDWWNDLNKKIQDNKRKVQE 356

Query: 361 KEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT 420
                   LNY  V+  L+ ++     I+V+EGANTMDI R       PR RLDAGT  T
Sbjct: 357 MTLDVSEPLNYYAVFHHLQEVLPQ-NPIIVSEGANTMDIGRAVLMNGLPRHRLDAGTFGT 415

Query: 421 MGIGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGI 476
           MG+GLG+A+A    C+   P+  V+ ++GDSAFGFS MEIET VR +L ++IVV+NNSGI
Sbjct: 416 MGVGLGFAIAAALYCRHFEPKKRVICVEGDSAFGFSGMEIETMVRYKLPVIIVVVNNSGI 475

Query: 477 YHG-EKDIEGDL----------PPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQA 525
           Y G  +++  DL          PPT L  +  Y+ +    G   +   TI+EL +  ++A
Sbjct: 476 YGGLPQEVYKDLQESGEVTKVTPPTTLFTSTHYEKMMTMFGRQGYHCTTIAELQKAVKEA 535

Query: 526 VQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           +   +     S+INVII P  ++K   F W  + +L
Sbjct: 536 L---KETEGPSIINVIISPSADRKPQDFNWLTESKL 568
>ref|NP_001092419.1| 2-hydroxyphytanoyl-CoA lyase [Bos taurus]
 gb|AAI42161.1| MGC160090 protein [Bos taurus]
          Length = 581

 Score =  370 bits (951), Expect = e-100,   Method: Composition-based stats.
 Identities = 224/573 (39%), Positives = 325/573 (56%), Gaps = 37/573 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+   ++ +FGIVGIP+ ++A      GI++I  RNEQAA YAASA GY++ +PGV 
Sbjct: 24  AQALKTQDVNYMFGIVGIPVTEIALAAQEVGIRYIGMRNEQAACYAASAVGYLTGRPGVC 83

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+V GPGL+H+L G+ N+  N WPL+VI GSS +S    G FQE  QV     + KF+ +
Sbjct: 84  LVVSGPGLVHSLGGMANANMNCWPLIVIGGSSERSQETMGAFQEFPQVEACRLYSKFSAR 143

Query: 130 LTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNIC 188
            +  + I  I +KA+   I G  G  Y+D+PADF+     L+ N  +   +   + P I 
Sbjct: 144 PSSIEAIPSIIEKAVRSSIYGRPGACYVDIPADFVS----LQVNVSSVKYVECCMPPPIS 199

Query: 189 GPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKGIV 246
             + S ++    +I     K  L++IGKGA     E  IR+LV    LPFLPTPM KG++
Sbjct: 200 MAETSAVRMAASVI--RNAKQPLVIIGKGAAYAHAEESIRKLVEQCKLPFLPTPMGKGVI 257

Query: 247 PDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDN 306
            D+ P  V++ARS+AL+ AD++++LGARLNWILHFG  P++  +  FIQ D   E LG N
Sbjct: 258 RDNHPNCVAAARSRALQFADVIVLLGARLNWILHFGLPPRYQPDVKFIQVDICAEELG-N 316

Query: 307 NVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEK 363
           NV P   +++ GD+      L+E+  +  + W+Y   S   + +REK++ N+        
Sbjct: 317 NVRPA--VTLLGDVNAVTKQLLEQFDK--TPWQYPPESEWWKVLREKMKSNEALSKELAS 372

Query: 364 TRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGI 423
            +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT  TMG+
Sbjct: 373 KKSLPMNYYTVFYHVQEQLPR-ECFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGV 431

Query: 424 GLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHG 479
           GLG+A+A     K  +P   V+ ++GDSAFGFS ME+ET  R  L +V++V+NN+GIY G
Sbjct: 432 GLGFAIAAAIVAKDRNPGQRVICVEGDSAFGFSGMEVETICRYNLPIVLLVVNNNGIYQG 491

Query: 480 -------EKDIEGD----LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQL 528
                  E    GD     PP  L  +  Y+ V    G   +FV T  EL +  +Q++  
Sbjct: 492 FDTDSWKEMLKFGDATTVAPPMCLLPHSHYEHVMTAFGGKGYFVQTPEELQKSLRQSLA- 550

Query: 529 SRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
                  S+IN++IEP G +K   F W  +  L
Sbjct: 551 --DTTNPSLINIMIEPQGTRKAQDFHWLTRSNL 581
>ref|XP_001782528.1| predicted protein [Physcomitrella patens subsp. patens]
 gb|EDQ52680.1| predicted protein [Physcomitrella patens subsp. patens]
          Length = 578

 Score =  369 bits (948), Expect = e-100,   Method: Composition-based stats.
 Identities = 223/562 (39%), Positives = 320/562 (56%), Gaps = 42/562 (7%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           A+   K G++T++G+VGIP+   A + V  G++FI   NEQ+A YAASA GY++ KPGVL
Sbjct: 19  ARAFAKMGVETMYGVVGIPVTSFASSCVKVGVRFIAFHNEQSAGYAASASGYLTGKPGVL 78

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L V GPG +H LAG+ N+  N WP+++++GSS Q+DI KG FQELDQ+ ++ PF K+ GK
Sbjct: 79  LTVSGPGCVHGLAGLSNAQINTWPMILVSGSSVQADIGKGDFQELDQLEIVKPFAKYAGK 138

Query: 130 L-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNIC 188
                 I  +  +A+   + G  G +Y+D+PAD +  E      +    EL   L P + 
Sbjct: 139 AHNIKEIPKVVAQAVTVSVSGRPGGTYVDLPADVLHEEV----TEDEAVELLADLKPYVP 194

Query: 189 -----GPDP------SKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLP 235
                GP        S+I +   L+     K  LIV GKGA  +  E  ++ LV +  +P
Sbjct: 195 AWAQEGPRKEFAAGDSEISEAASLL--RNAKRPLIVFGKGAAFSRAEGALKNLVESTGIP 252

Query: 236 FLPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQ 295
           FL TPMAKGI+PD+ PL+ S+ARS A+  AD+ LV+GARLNW+LHFG +P+W+ +  FI 
Sbjct: 253 FLATPMAKGILPDAHPLSASAARSLAIGEADVALVVGARLNWLLHFGEAPRWSKDVKFIL 312

Query: 296 FDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCW--KYSGVKQEIREKIQL 353
            D + E +     +    L + GD  + +  L +E+  Q      K+  V Q+I+ K Q 
Sbjct: 313 VDVSKEEIEFRKPT----LGLVGDADVVIKQLNKEIKDQPFALGEKHEWV-QKIKSKAQS 367

Query: 354 NQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRT---ILVTEGANTMDIARISFPTDAPR 410
           N  R+           N+      +R  I    +   ILV+EGANTMD+ R       PR
Sbjct: 368 NVQRMAGSLNKVVVPFNFLTPMKIIRDAILSVGSPAPILVSEGANTMDVGRSVLEQTEPR 427

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
            RLDAGT  TMG+GLGY +A   ++PE  VV ++GDS FGFS +E+ET VR +L +V+++
Sbjct: 428 TRLDAGTWGTMGVGLGYCIAAAVTNPEKLVVAVEGDSGFGFSGLEVETLVRYKLPVVVII 487

Query: 471 MNNSGIYHGEK----DIEG----DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
            NN G+Y G++    DI G    D  PT+     RYDLV +  G   + V    EL    
Sbjct: 488 FNNGGVYGGDRRPAEDIVGPHKDDPAPTSFVPGARYDLVMEAFGGKGYLVENPEEL---- 543

Query: 523 QQAVQLSRTKRETSVINVIIEP 544
           Q A++ S   R+ +VINV I+P
Sbjct: 544 QSALKESFAARKPAVINVTIDP 565
>gb|EDL24815.1| 2-hydroxyacyl-CoA lyase 1 [Mus musculus]
          Length = 587

 Score =  369 bits (947), Expect = e-100,   Method: Composition-based stats.
 Identities = 226/574 (39%), Positives = 320/574 (55%), Gaps = 39/574 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+   ++ +FG+VGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV 
Sbjct: 30  AQALKTQDVEYMFGVVGIPVTEIALAAQELGIKYIGMRNEQAACYAASAVGYLTGRPGVC 89

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+V GPGLIHAL G+ N+  N WPL+VI GSS ++    G FQE  QV     + KF+ +
Sbjct: 90  LVVSGPGLIHALGGMANANMNCWPLIVIGGSSERNQEAMGAFQEFPQVEACRLYTKFSAR 149

Query: 130 LTPDNIDM---ITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPN 186
             P  I++   I +KA+   I G  G  YID+PADF+     L+ N  +       + P 
Sbjct: 150 --PSTIELIPFIIEKAVRSSIYGRPGACYIDIPADFVT----LQANVTSIKYKECCMPPP 203

Query: 187 ICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKG 244
           +   + S +     ++   K    L++IGKGA  +  E  IR+LV   +LPFLPTPM KG
Sbjct: 204 VSMAETSAVCAAASVLRDAKQP--LLIIGKGAAYSHAEDSIRKLVEQCSLPFLPTPMGKG 261

Query: 245 IVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLG 304
           +VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++ ++  FIQ D   E LG
Sbjct: 262 VVPDNHPNCVGAARSRALQSADVIVLFGARLNWILHFGLPPRYQADVKFIQIDICAEELG 321

Query: 305 DNNVSPGADLSIWGDIGLSVTALVEELTRQD-SCWKYSGVKQEIREKIQLNQTRLLRKEK 363
            NNV P   L   GDI      L+E+  +    C   S   + +REK++ N+        
Sbjct: 322 -NNVRPSVIL--LGDIDAVSKQLLEQFDKTPWQCPPDSQWWKTLREKMKSNEAISKELAS 378

Query: 364 TRGAQLNYNQV-YGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMG 422
            +   +NY  V Y     L  D  + +V+EGANTMDI R       PR RLDAG+  TMG
Sbjct: 379 QKSLPMNYYTVFYHVQEQLPRD--SFIVSEGANTMDIGRTMLQNCLPRHRLDAGSFGTMG 436

Query: 423 IGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYH 478
           +GLG+A+A     K   P   V+ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY 
Sbjct: 437 VGLGFAIAAALVAKDRSPGQRVICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQ 496

Query: 479 G------EK-----DIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           G      EK     +    +PP  L  N  Y+ V    G   +FV T  EL    +QA+Q
Sbjct: 497 GFDADTWEKMLHFQEAATTVPPMCLLPNSHYEQVMTAFGGKGYFVRTPEELQHSLRQALQ 556

Query: 528 LSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
                 +  ++N++IEP   +K   F W  +  +
Sbjct: 557 ---DTSKPCLLNIMIEPQSTRKAQDFHWLTRSNM 587
>ref|NP_445945.1| 2-hydroxyacyl-CoA lyase 1 [Rattus norvegicus]
 sp|Q8CHM7|HACL1_RAT 2-hydroxyacyl-CoA lyase 1 (2-hydroxyphytanoyl-CoA lyase) (2-HPCL)
           (Phytanoyl-CoA 2-hydroxylase 2)
 emb|CAD56981.1| 2-hydroxyphytanoyl-CoA lyase [Rattus norvegicus]
 gb|AAH78697.1| Phytanoyl-CoA 2-hydroxylase 2 [Rattus norvegicus]
 gb|EDL88941.1| phytanoyl-CoA 2-hydroxylase 2 [Rattus norvegicus]
          Length = 581

 Score =  369 bits (947), Expect = e-100,   Method: Composition-based stats.
 Identities = 221/573 (38%), Positives = 321/573 (56%), Gaps = 37/573 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+   ++ +FG+VGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV 
Sbjct: 24  AQALKTQDVEYMFGVVGIPVTEIALAAQELGIKYIGMRNEQAACYAASAVGYLTGRPGVC 83

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+V GPGLIHAL G+ N+  N WPL+VI GSS ++    G FQE  QV     + KF+ +
Sbjct: 84  LVVSGPGLIHALGGMANANMNCWPLIVIGGSSERNQEAMGAFQEFPQVEACRLYSKFSAR 143

Query: 130 LTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNIC 188
            +   +I  + +KA+   I G  G  YIDVPAD +  ++           +P    P + 
Sbjct: 144 PSSIQHIPFVIEKAVRSSIYGRPGACYIDVPADLVTLQESTTSIKYKECCMP----PPLS 199

Query: 189 GPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKGIV 246
             + S ++    ++     K  L++IGKGA  +  E  IR+LV   NLPFLPTPM KG+V
Sbjct: 200 LAETSAVRAAASVL--RSAKQPLLIIGKGAAYSHAEDSIRKLVELCNLPFLPTPMGKGVV 257

Query: 247 PDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDN 306
           PD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++ ++  FIQ D   E LG N
Sbjct: 258 PDNHPNCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQADVKFIQIDICAEELG-N 316

Query: 307 NVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEK 363
           NV P   +++ GD+      L+E+  +    W+Y   S   + +REK + N+        
Sbjct: 317 NVRP--SVTLLGDVNAVSKQLLEQFVKNP--WQYPTDSKWWETLREKRKNNEAVSKELAS 372

Query: 364 TRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGI 423
            +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAG+  TMG+
Sbjct: 373 KKSLPMNYYTVFYHVQEQLPR-NCFIVSEGANTMDIGRTVLQNYLPRHRLDAGSFGTMGV 431

Query: 424 GLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHG 479
           GLG+A+A     K   P   V+ ++GDSAFGFS ME+ET  R  L ++I+V+NN+GIY G
Sbjct: 432 GLGFAIAAAVVAKERSPGQRVICVEGDSAFGFSGMEVETICRYNLPIIILVVNNNGIYQG 491

Query: 480 -EKDIEGD----------LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQL 528
            + D  G           +PP  L  N  Y+ V    G   +FV T  EL    +QA+  
Sbjct: 492 FDADTWGKILNFQGTATTIPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQDSLRQAL-- 549

Query: 529 SRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
            +   +  +IN++IEP   +K   F W  +  +
Sbjct: 550 -KDTSKPCLINIMIEPQSTRKAQDFHWLTRSNI 581
>ref|NP_064359.2| 2-hydroxyacyl-CoA lyase 1 [Mus musculus]
 sp|Q9QXE0|HACL1_MOUSE 2-hydroxyacyl-CoA lyase 1 (2-hydroxyphytanoyl-CoA lyase) (2-HPCL)
           (Phytanoyl-CoA 2-hydroxylase 2)
 dbj|BAB24085.1| unnamed protein product [Mus musculus]
 gb|AAH21360.1| 2-hydroxyacyl-CoA lyase 1 [Mus musculus]
 dbj|BAC31032.1| unnamed protein product [Mus musculus]
 dbj|BAC34059.1| unnamed protein product [Mus musculus]
          Length = 581

 Score =  368 bits (945), Expect = e-100,   Method: Composition-based stats.
 Identities = 226/574 (39%), Positives = 320/574 (55%), Gaps = 39/574 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+   ++ +FG+VGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV 
Sbjct: 24  AQALKTQDVEYMFGVVGIPVTEIALAAQELGIKYIGMRNEQAACYAASAVGYLTGRPGVC 83

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+V GPGLIHAL G+ N+  N WPL+VI GSS ++    G FQE  QV     + KF+ +
Sbjct: 84  LVVSGPGLIHALGGMANANMNCWPLIVIGGSSERNQEAMGAFQEFPQVEACRLYTKFSAR 143

Query: 130 LTPDNIDM---ITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPN 186
             P  I++   I +KA+   I G  G  YID+PADF+     L+ N  +       + P 
Sbjct: 144 --PSTIELIPFIIEKAVRSSIYGRPGACYIDIPADFVT----LQANVTSIKYKECCMPPP 197

Query: 187 ICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKG 244
           +   + S +     ++   K    L++IGKGA  +  E  IR+LV   +LPFLPTPM KG
Sbjct: 198 VSMAETSAVCAAASVLRDAKQP--LLIIGKGAAYSHAEDSIRKLVEQCSLPFLPTPMGKG 255

Query: 245 IVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLG 304
           +VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++ ++  FIQ D   E LG
Sbjct: 256 VVPDNHPNCVGAARSRALQSADVIVLFGARLNWILHFGLPPRYQADVKFIQIDICAEELG 315

Query: 305 DNNVSPGADLSIWGDIGLSVTALVEELTRQD-SCWKYSGVKQEIREKIQLNQTRLLRKEK 363
            NNV P   L   GDI      L+E+  +    C   S   + +REK++ N+        
Sbjct: 316 -NNVRPSVIL--LGDIDAVSKQLLEQFDKTPWQCPPDSQWWKTLREKMKSNEAISKELAS 372

Query: 364 TRGAQLNYNQV-YGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMG 422
            +   +NY  V Y     L  D  + +V+EGANTMDI R       PR RLDAG+  TMG
Sbjct: 373 QKSLPMNYYTVFYHVQEQLPRD--SFIVSEGANTMDIGRTMLQNCLPRHRLDAGSFGTMG 430

Query: 423 IGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYH 478
           +GLG+A+A     K   P   V+ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY 
Sbjct: 431 VGLGFAIAAALVAKDRSPGQRVICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQ 490

Query: 479 G------EK-----DIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           G      EK     +    +PP  L  N  Y+ V    G   +FV T  EL    +QA+Q
Sbjct: 491 GFDADTWEKMLHFQEAATTVPPMCLLPNSHYEQVMTAFGGKGYFVRTPEELQHSLRQALQ 550

Query: 528 LSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
                 +  ++N++IEP   +K   F W  +  +
Sbjct: 551 ---DTSKPCLLNIMIEPQSTRKAQDFHWLTRSNM 581
>ref|XP_001629607.1| predicted protein [Nematostella vectensis]
 gb|EDO37544.1| predicted protein [Nematostella vectensis]
          Length = 580

 Score =  367 bits (942), Expect = 1e-99,   Method: Composition-based stats.
 Identities = 216/586 (36%), Positives = 331/586 (56%), Gaps = 40/586 (6%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
           T +     A+ L+  G + +FG+VGIP++++A    A GIK++  RNEQ+A YAASA GY
Sbjct: 8   TLSGATLLARALRAQGCEYMFGVVGIPVIEIAIAAQAEGIKYVGMRNEQSACYAASAIGY 67

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGL+HAL G+ N+  N WP+LVI GSS      +G FQE+ QV    
Sbjct: 68  LTRRPGVCLVVSGPGLLHALGGLANATENCWPVLVIGGSSDLDQEGQGAFQEIPQVEAAK 127

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
           P+ K++ + +   +I    +KA+   I G  G  Y+D+P + +  E+      +  ++ P
Sbjct: 128 PYCKYSARPSSIHSIGFFVEKAVRTSIYGRPGACYLDIPGNMVN-EEVQACKAKVFSQCP 186

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLP 238
               P  C  D S +K+ V+L+   K +  L++IGKGA  +  E  +  +++   LPFLP
Sbjct: 187 ---APPKCLADYSSVKQAVELL--SKAEKPLVIIGKGAAYSHAERPLLEMIDRCKLPFLP 241

Query: 239 TPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDS 298
           TPM KG++ D  PL V+ ARS AL  AD++L+ GARLNW+LHFG +P++  +  FIQ D 
Sbjct: 242 TPMGKGVISDDHPLCVAPARSLALSNADVILLCGARLNWMLHFGKAPRFRKDVKFIQVDI 301

Query: 299 NPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTR- 357
           + E +G NNVS G  + ++GD+   +  + E +T++ +  +   + +     +QLN+   
Sbjct: 302 HAEEMG-NNVSSG--IFLYGDLPGVIEQITERITKRGNIMQAEKLSE---WTVQLNKKSE 355

Query: 358 ---LLRKEKTR--GAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRR 412
              ++ KE +      ++Y Q YG ++  +      +V EGANTMDI R   P   PRRR
Sbjct: 356 RNLMMNKELSSVVTVPMSYYQAYGQIKKFLPQ-DCFIVNEGANTMDIGRTMMPNHFPRRR 414

Query: 413 LDAGTNATMGIGLGYALAC---------KASHPELDVVLIQGDSAFGFSAMEIETAVRCQ 463
           LDAGT  TMG+G G+A+A          +   P   VV IQGDSAFGFS ME+ET+ R  
Sbjct: 415 LDAGTFGTMGVGTGFAIAAAMLAEGQAEQRGLPAERVVCIQGDSAFGFSGMELETSCRYN 474

Query: 464 LALVIVVMNNSGIYHGEKDIEGDLP--------PTALSKNCRYDLVGKGLGANDFFVNTI 515
           L +V +V+NN+GI  G      D          P ALS N  Y+ + +  G   +   T 
Sbjct: 475 LPIVFIVINNNGIGTGMDQDSWDAIKKPALEALPMALSPNASYEKMMEAFGGKGYCAQTS 534

Query: 516 SELSRCFQQAVQLSRTKRETSVINVIIE-PGEQKQIAFAWQNKPRL 560
           +EL +  +QA   + T  + ++INVII+   ++K   F W  + ++
Sbjct: 535 AELHKALEQAFYNTATTCKPALINVIIDTSADRKPQDFHWLTRSKM 580
>ref|XP_001495031.1| PREDICTED: similar to 2-hydroxyacyl-CoA lyase 1 [Equus caballus]
          Length = 581

 Score =  367 bits (941), Expect = 2e-99,   Method: Composition-based stats.
 Identities = 225/574 (39%), Positives = 324/574 (56%), Gaps = 39/574 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+  G+  +FG+VGIP+ ++A      GI+++  RNEQAA YAAS  GY++D+PGV 
Sbjct: 24  AQALKTQGVKYMFGVVGIPVTEIAFAAQELGIRYVGMRNEQAACYAASVVGYLTDRPGVC 83

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+  GPGLI+AL+G+ N+  N WPLLVI GS  +S    G FQEL QV     + KF+ +
Sbjct: 84  LVTSGPGLINALSGMANANMNCWPLLVIGGSCERSQETMGAFQELPQVETCRLYSKFSAR 143

Query: 130 LTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNIC 188
            +    I  I +KA+   + G  G  Y+D+PAD ++    L+ N  +   +   + P + 
Sbjct: 144 PSSIQAIPSIIEKAVRSSMYGRPGACYVDMPADIVD----LKVNVSSIKYVECCMPPPVS 199

Query: 189 GPDPSKIKKVVQLILQHKNKNILIVIGKGA--VKNSHEIRRLVNTFNLPFLPTPMAKGIV 246
             + S +     ++     K  LI+IGKGA   +    +R+LV    LPFLPTPM KG++
Sbjct: 200 MAEGSAVCMAASVL--RNAKQPLIIIGKGAAYARAEEAVRKLVEQCKLPFLPTPMGKGVI 257

Query: 247 PDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDN 306
           PD+ P  V +ARS+AL++AD++++ GARLNWILHFG  P++  +  FIQ D   E LG N
Sbjct: 258 PDNHPNCVGAARSRALQLADVIVLFGARLNWILHFGLPPRFRPDVKFIQVDICAEELG-N 316

Query: 307 NVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEK 363
           NV P   +++ GDI      L+E+  R  + W+Y   S   + +REK++ N+        
Sbjct: 317 NVRPA--VTLLGDINAVTKQLLEQFDR--TPWQYPPESKWWKTLREKMKSNEAVTKELAS 372

Query: 364 TRGAQLNYNQV-YGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMG 422
                +NY  V Y     L  D    +V+EGANTMDI R       PR RLDAGT  TMG
Sbjct: 373 KNSLPMNYFTVFYHVQEQLPKD--CFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMG 430

Query: 423 IGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYH 478
           +GLG+A+A     K  +P   V+ ++GDSAFGFS +E+ET  R  L +V++V+NN+GIY 
Sbjct: 431 VGLGFAIAAAVVAKDRNPGQRVICVEGDSAFGFSGLEVETICRYNLPIVLLVVNNNGIYQ 490

Query: 479 G-------EKDIEGD----LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           G       E    GD     PP +L  N  Y+ V    G   +FV T  EL +C  Q+  
Sbjct: 491 GFNADTWKEMLKFGDATFVAPPLSLLPNAHYEQVMTAFGGKGYFVQTPEELQKCLSQS-- 548

Query: 528 LSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           L+ T +  S+IN++IEP   +K   F W  +  +
Sbjct: 549 LADTTK-PSLINIMIEPQATRKPQEFHWLTRSNI 581
>emb|CAB65550.1| 2-hydroxyphytanoyl-CoA lyase [Mus musculus]
          Length = 581

 Score =  366 bits (940), Expect = 3e-99,   Method: Composition-based stats.
 Identities = 225/574 (39%), Positives = 320/574 (55%), Gaps = 39/574 (6%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
           AQ L+   ++ +FG+VGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV 
Sbjct: 24  AQALKTQDVEYMFGVVGIPVTEIALAAQELGIKYIGMRNEQAACYAASAVGYLTGRPGVC 83

Query: 70  LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
           L+V GPGLIHAL G+ N+  N WPL+VI GSS ++    G FQE  QV     + KF+ +
Sbjct: 84  LVVSGPGLIHALGGMANANMNCWPLIVIGGSSERNQEAMGAFQEFPQVEACRLYTKFSAR 143

Query: 130 LTPDNIDM---ITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPN 186
             P  I++   I +KA+   I G  G  YID+PADF+     L+ N  +       + P 
Sbjct: 144 --PSTIELIPFIIEKAVRSSIYGRPGACYIDIPADFVT----LQANVTSIKYKECCMPPP 197

Query: 187 ICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAKG 244
           +   + S +     ++   K    L++IGKGA  +  E  IR+LV   +LPFLPTP+ KG
Sbjct: 198 VSMAETSAVCAAASVLRDAKQP--LLIIGKGAAYSHAEDSIRKLVEQCSLPFLPTPIGKG 255

Query: 245 IVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLG 304
           +VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++ ++  FIQ D   E LG
Sbjct: 256 VVPDNHPNCVGAARSRALQSADVIVLFGARLNWILHFGLPPRYQADVKFIQIDICAEELG 315

Query: 305 DNNVSPGADLSIWGDIGLSVTALVEELTRQD-SCWKYSGVKQEIREKIQLNQTRLLRKEK 363
            NNV P   L   GDI      L+E+  +    C   S   + +REK++ N+        
Sbjct: 316 -NNVRPSVIL--LGDIDAVSKQLLEQFDKTPWQCPPDSQWWKTLREKMKSNEAISKELAS 372

Query: 364 TRGAQLNYNQV-YGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMG 422
            +   +NY  V Y     L  D  + +V+EGANTMDI R       PR RLDAG+  TMG
Sbjct: 373 QKSLPMNYYTVFYHVQEQLPRD--SFIVSEGANTMDIGRTMLQNCLPRHRLDAGSFGTMG 430

Query: 423 IGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYH 478
           +GLG+A+A     K   P   V+ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY 
Sbjct: 431 VGLGFAIAAALVAKDRSPGQRVICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQ 490

Query: 479 G------EK-----DIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           G      EK     +    +PP  L  N  Y+ V    G   +FV T  EL    +QA+Q
Sbjct: 491 GFDADTWEKMLHFQEAATTVPPMCLLPNSHYEQVMTAFGGKGYFVRTPEELQHSLRQALQ 550

Query: 528 LSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
                 +  ++N++IEP   +K   F W  +  +
Sbjct: 551 ---DTSKPCLLNIMIEPQSTRKAQDFHWLTRSNM 581
>ref|XP_001660326.1| 2-hydroxyphytanoyl-coa lyase [Aedes aegypti]
 gb|EAT38352.1| 2-hydroxyphytanoyl-coa lyase [Aedes aegypti]
          Length = 567

 Score =  363 bits (931), Expect = 2e-98,   Method: Composition-based stats.
 Identities = 233/580 (40%), Positives = 334/580 (57%), Gaps = 49/580 (8%)

Query: 9   FAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGV 68
            A+ L++ G++ VFGIVGIP+V+L+  M A G+K+I  RNEQ+A YAA A GY++ KPGV
Sbjct: 9   LARSLKEQGVEYVFGIVGIPVVELSMAMQAEGLKYIGMRNEQSACYAAQAIGYLTGKPGV 68

Query: 69  LLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTG 128
            L+V GPGL+H  AG+ N+  N WPL+V+AG++ Q     G FQE  QV L  P+ K+  
Sbjct: 69  CLVVPGPGLLHVTAGMANAQINCWPLIVVAGAAFQDHEGIGAFQECPQVDLSRPYCKYAA 128

Query: 129 KLTPDNIDMITQ---KALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTP 185
           +  P +I +I Q   KA+     G  GV+Y+D+P + +    P    D    +      P
Sbjct: 129 R--PASIPLIPQHVEKAVRLACYGRPGVAYLDMPGNLLLARVP---EDSVPKQYVHPERP 183

Query: 186 NICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAK 243
            I  PD   IK+   L+   K K  L+++GKGA     E  +R+LV+  NLPFLPTPM K
Sbjct: 184 -IAFPDTKSIKEAAHLLA--KAKRPLVIVGKGAAYAHAELHLRQLVHQTNLPFLPTPMGK 240

Query: 244 GIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETL 303
           G+VPD  P  V+ AR+ AL+ AD++L+LGARLNW+LHFG  P+++     IQ D + E L
Sbjct: 241 GVVPDLDPQCVAPARTLALQKADVILLLGARLNWMLHFGRQPRFSPNVKIIQVDLSAEEL 300

Query: 304 GDNNVSPGADLSIWGDIGLSVTALVEELT-------RQDSCWKYSGVKQEIREKIQLNQT 356
            ++ +S    +++  DI      L++EL        + +  W       +++ K + N+ 
Sbjct: 301 HNSVMS---SVAVQSDIVPFTEQLIDELASMHFYFDKNNDWWI------DLKAKCEKNKK 351

Query: 357 RLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAG 416
            + +    +   LNY+ V+  L+ LI     I+V+EGANTMDI R       PR RLDAG
Sbjct: 352 IVQQMAMDKKVPLNYHAVFHHLQELIPK-DAIIVSEGANTMDIGRTFLHNKWPRHRLDAG 410

Query: 417 TNATMGIGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMN 472
           T  TMG+G G+A+A    C+   P   V+ ++GDSAFGFS MEIET VR QL +VIVV+N
Sbjct: 411 TFGTMGVGPGFAIAAALVCRDRFPGEKVICVEGDSAFGFSGMEIETMVRYQLPVVIVVVN 470

Query: 473 NSGIYHG-------EKDIEGDL----PPTALSKNCRYDLVGKGLGANDFFVNTISELSRC 521
           N+GIY G       E    GDL    PP+AL+    Y+ +    G    F+ +I EL + 
Sbjct: 471 NNGIYSGFDLEAYNEMRTAGDLTKVTPPSALNVETHYEAMMNMFGLKGHFIRSIPELQQA 530

Query: 522 FQQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
            ++A+ L  T R T +INVII P  ++K   F W  + +L
Sbjct: 531 VKEALTL--TDRPT-IINVIISPTADRKPQDFQWLTESKL 567
>ref|XP_001649370.1| 2-hydroxyphytanoyl-coa lyase [Aedes aegypti]
 gb|EAT33038.1| 2-hydroxyphytanoyl-coa lyase [Aedes aegypti]
          Length = 567

 Score =  362 bits (930), Expect = 4e-98,   Method: Composition-based stats.
 Identities = 234/581 (40%), Positives = 336/581 (57%), Gaps = 51/581 (8%)

Query: 9   FAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGV 68
            A+ L++ G++ VFGIVGIP+V+L+  M A G+K+I  RNEQ+A YAA A GY++ KPGV
Sbjct: 9   LARSLKEQGVEYVFGIVGIPVVELSMAMQAEGLKYIGMRNEQSACYAAQAIGYLTGKPGV 68

Query: 69  LLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTG 128
            L+V GPGL+H  AG+ N+  N WPL+V+AG++ Q     G FQE  QV L  P+ K+  
Sbjct: 69  CLVVPGPGLLHVTAGMANAQINCWPLIVVAGAAFQDHEGIGAFQECPQVDLSRPYCKYAA 128

Query: 129 KLTPDNIDMITQ---KALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTP 185
           +  P +I +I Q   KA+     G  GV+Y+D+P + +    P    D    +      P
Sbjct: 129 R--PASIPLIPQHVEKAVRLACYGRPGVAYLDMPGNLLLARVP---EDSVPKQYVHPERP 183

Query: 186 NICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTPMAK 243
            I  PD   +K+   L+   K K  L+++GKGA     E  +R+LV+  NLPFLPTPM K
Sbjct: 184 -IAFPDTKSVKEAAHLLA--KAKRPLVIVGKGAAYAHAELHLRQLVHQTNLPFLPTPMGK 240

Query: 244 GIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETL 303
           G+VPD  P  V+ AR+ AL+ AD++L+LGARLNW+LHFG  P+++     IQ D + E L
Sbjct: 241 GVVPDLDPQCVAPARTLALQKADVILLLGARLNWMLHFGRQPRFSPNVKIIQVDLSAEEL 300

Query: 304 GDNNVSPGADLSIWGDIGLSVTALVEELT-------RQDSCWKYSGVKQEIREKIQLNQT 356
            ++ +S    +++  DI      L++EL        + +  W       +++ K + N+ 
Sbjct: 301 HNSVLS---SVAVQSDIVPFTEQLIDELASMHFYFDKNNDWWI------DLKAKCEKNKK 351

Query: 357 RLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAG 416
            + +    +   LNY+ V+  L+ LI     I+V+EGANTMDI R       PR RLDAG
Sbjct: 352 IVQQMAMDKKVPLNYHAVFHHLQELIPK-DAIIVSEGANTMDIGRTFLHNKWPRHRLDAG 410

Query: 417 TNATMGIGLGYALA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMN 472
           T  TMG+G G+A+A    C+   P   V+ ++GDSAFGFS MEIET VR QL +VIVV+N
Sbjct: 411 TFGTMGVGPGFAIAAALVCRDRFPGEKVICVEGDSAFGFSGMEIETMVRYQLPVVIVVVN 470

Query: 473 NSGIYHGEKDIE--------GDL----PPTALSKNCRYDLVGKGLGANDFFVNTISELSR 520
           N+GIY G  D+E        GDL    PP+AL+    Y+ +    G    F+ TI EL +
Sbjct: 471 NNGIYSG-FDLEAYNDMRTAGDLTKVTPPSALNVETHYEAMMNMFGLKGHFIRTIPELQQ 529

Query: 521 CFQQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
             ++A+ L  T R T +INVII P  ++K   F W  + +L
Sbjct: 530 AVKEALTL--TDRPT-IINVIISPTADRKPQDFQWLTESKL 567
Searching..................................................done Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|NP_010895.1|  hypothetical protein with low sequence ide...   749   0.0  
gb|EDN62949.1|  conserved protein [Saccharomyces cerevisiae ...   748   0.0  
ref|XP_001160528.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   662   0.0  
gb|AAF28957.1|AF161397_1  HSPC279 [Homo sapiens]                  660   0.0  
ref|XP_534256.2|  PREDICTED: similar to 2-hydroxyphytanoyl-C...   660   0.0  
emb|CAB60200.1|  2-hydroxyphytanoyl-CoA lyase [Homo sapiens]      660   0.0  
ref|NP_036392.2|  2-hydroxyphytanoyl-CoA lyase [Homo sapiens...   659   0.0  
ref|XP_418737.2|  PREDICTED: hypothetical protein [Gallus ga...   655   0.0  
gb|EDL24815.1|  2-hydroxyacyl-CoA lyase 1 [Mus musculus]          654   0.0  
ref|NP_445945.1|  2-hydroxyacyl-CoA lyase 1 [Rattus norvegic...   654   0.0  
ref|NP_064359.2|  2-hydroxyacyl-CoA lyase 1 [Mus musculus] >...   653   0.0  
emb|CAB65550.1|  2-hydroxyphytanoyl-CoA lyase [Mus musculus]      649   0.0  
ref|XP_001160323.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   648   0.0  
ref|XP_001495031.1|  PREDICTED: similar to 2-hydroxyacyl-CoA...   648   0.0  
ref|XP_001160179.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   648   0.0  
ref|XP_001160421.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   647   0.0  
ref|NP_001086822.1|  MGC82654 protein [Xenopus laevis] >gi|5...   645   0.0  
ref|XP_001160475.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   645   0.0  
ref|NP_001092419.1|  2-hydroxyphytanoyl-CoA lyase [Bos tauru...   643   0.0  
ref|ZP_02177150.1|  acetolactate synthase large subunit [Hyd...   639   0.0  
ref|NP_001017332.1|  hypothetical protein LOC550086 [Xenopus...   637   0.0  
ref|ZP_00822285.1|  COG0028: Thiamine pyrophosphate-requirin...   635   e-180
ref|ZP_00825910.1|  COG0028: Thiamine pyrophosphate-requirin...   634   e-180
ref|NP_613816.1|  acetolactate synthase catalytic subunit [M...   632   e-179
ref|ZP_00831646.1|  COG0028: Thiamine pyrophosphate-requirin...   631   e-179
ref|ZP_02478424.1|  acetolactate synthase 3 catalytic subuni...   630   e-179
ref|ZP_00833010.1|  COG0028: Thiamine pyrophosphate-requirin...   630   e-179
ref|NP_213319.1|  acetolactate synthase large subunit [Aquif...   630   e-179
ref|XP_975143.1|  PREDICTED: similar to CG11208-PA [Triboliu...   629   e-178
ref|ZP_01991840.1|  acetolactate synthase, large subunit, bi...   628   e-178
ref|YP_001005008.1|  acetolactate synthase 3 catalytic subun...   628   e-178
ref|NP_796731.1|  acetolactate synthase 3 catalytic subunit ...   627   e-178
ref|ZP_02961406.1|  hypothetical protein PROSTU_03434 [Provi...   627   e-178
ref|ZP_01261609.1|  acetolactate synthase III large subunit ...   627   e-178
ref|YP_001444053.1|  acetolactate synthase III, large subuni...   627   e-178
ref|XP_001160372.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   627   e-178
ref|ZP_01814076.1|  acetolactate synthase III large subunit ...   627   e-178
ref|YP_001476982.1|  acetolactate synthase, large subunit, b...   626   e-177
ref|NP_759633.1|  acetolactate synthase 3 catalytic subunit ...   626   e-177
ref|YP_001607309.1|  acetolactate synthase, large subunit, b...   625   e-177
ref|ZP_01986889.1|  acetolactate synthase, large subunit, bi...   625   e-177
ref|ZP_01161985.1|  acetolactate synthase III large subunit ...   625   e-177
ref|ZP_01474203.1|  hypothetical protein VEx2w_02003241 [Vib...   625   e-177
ref|ZP_00992427.1|  acetolactate synthase III large subunit ...   624   e-177
ref|NP_404181.1|  acetolactate synthase 3 catalytic subunit ...   624   e-177
ref|ZP_01066405.1|  acetolactate synthase III large subunit ...   624   e-177
ref|ZP_02196570.1|  acetolactate synthase III large subunit ...   624   e-177
ref|ZP_02179310.1|  acetolactate synthase large subunit [Hyd...   623   e-176
ref|ZP_01236581.1|  acetolactate synthase III large subunit ...   623   e-176
ref|YP_205646.1|  acetolactate synthase III, large subunit [...   622   e-176
ref|YP_001930430.1|  acetolactate synthase, large subunit, b...   622   e-176
ref|YP_001164433.1|  acetolactate synthase 3 catalytic subun...   621   e-176
ref|ZP_01389342.1|  acetolactate synthase, large subunit, bi...   621   e-176
ref|XP_001629607.1|  predicted protein [Nematostella vectens...   620   e-175
ref|ZP_03831127.1|  acetolactate synthase 3 catalytic subuni...   620   e-175
ref|ZP_03827861.1|  acetolactate synthase 3 catalytic subuni...   620   e-175
ref|YP_051917.1|  acetolactate synthase 3 catalytic subunit ...   619   e-175
ref|XP_001864201.1|  2-hydroxyacyl-CoA lyase 1 [Culex pipien...   618   e-175
ref|NP_930874.1|  acetolactate synthase 3 catalytic subunit ...   618   e-175
ref|NP_611460.1|  CG11208 CG11208-PA [Drosophila melanogaste...   618   e-175
ref|NP_276558.1|  acetolactate synthase catalytic subunit [M...   617   e-175
dbj|BAD72897.1|  unnamed protein product [Drosophila simulan...   617   e-175
ref|XP_001868099.1|  2-hydroxyphytanoyl-coa lyase [Culex pip...   617   e-174
ref|XP_001361932.1|  GA10842-PA [Drosophila pseudoobscura] >...   616   e-174
dbj|BAC86096.1|  unnamed protein product [Homo sapiens]           616   e-174
ref|YP_001232446.1|  acetolactate synthase, large subunit, b...   616   e-174
ref|YP_088511.1|  acetolactate synthase 3 catalytic subunit ...   615   e-174
ref|NP_127022.1|  acetolactate synthase, large subunit [Pyro...   615   e-174
gb|ABU63575.1|  AHAS catalytic subunit [Klebsiella pneumoniae]    614   e-174
ref|NP_439730.1|  acetolactate synthase 3 catalytic subunit ...   614   e-174
ref|ZP_00157121.1|  COG0028: Thiamine pyrophosphate-requirin...   614   e-174
gb|AAN78592.1|AE016755_92  Acetolactate synthase isozyme III...   614   e-174
ref|YP_001742200.1|  acetolactate synthase, large subunit, i...   613   e-174
ref|ZP_00349598.1|  COG0028: Thiamine pyrophosphate-requirin...   613   e-174
ref|YP_001279514.1|  acetolactate synthase 3 catalytic subun...   613   e-174
ref|YP_002806680.1|  acetolactate synthase [Escherichia sp. ...   613   e-174
ref|ZP_01983141.1|  acetolactate synthase III, large subunit...   613   e-173
ref|ZP_01793476.1|  acetolactate synthase 3 catalytic subuni...   613   e-173
ref|YP_001290857.1|  acetolactate synthase 3 catalytic subun...   613   e-173
ref|YP_001217983.1|  acetolactate synthase 3 catalytic subun...   613   e-173
ref|YP_851278.1|  acetolactate synthase 3 catalytic subunit ...   613   e-173
ref|ZP_01485182.1|  hypothetical protein VchoV5_02002207 [Vi...   612   e-173
ref|ZP_00923850.1|  COG0028: Thiamine pyrophosphate-requirin...   612   e-173
ref|NP_247250.1|  acetolactate synthase catalytic subunit [M...   612   e-173
ref|NP_232112.1|  acetolactate synthase 3 catalytic subunit ...   612   e-173
ref|ZP_00720987.1|  COG0028: Thiamine pyrophosphate-requirin...   612   e-173
gb|AAG54381.1|AE005184_9  acetolactate synthase III, valine ...   612   e-173
ref|YP_001439319.1|  hypothetical protein ESA_03261 [Enterob...   611   e-173
ref|ZP_00715653.1|  COG0028: Thiamine pyrophosphate-requirin...   611   e-173
ref|ZP_03835233.1|  acetolactate synthase 3 catalytic subuni...   611   e-173
ref|NP_578664.1|  acetolactate synthase [Pyrococcus furiosus...   611   e-173
ref|AP_000741.1|  acetolactate synthase III, large subunit [...   611   e-173
dbj|BAB33504.1|  putative acetolactate synthase III large su...   611   e-173
ref|YP_001243976.1|  acetolactate synthase, large subunit, b...   610   e-173
gb|EDN13953.1|  acetolactate synthase III, large subunit [Vi...   610   e-173
ref|ZP_00718693.1|  COG0028: Thiamine pyrophosphate-requirin...   610   e-173
gb|AAP15618.1|  acetolactate synthase III, large subunit [Sh...   610   e-173
ref|NP_752048.2|  acetolactate synthase 3 catalytic subunit ...   610   e-173
gb|EEH95023.1|  acetolactate synthase 3 catalytic subunit [C...   610   e-172
ref|YP_344503.1|  Acetolactate synthase, large subunit, bios...   610   e-172
ref|YP_406628.1|  acetolactate synthase 3 catalytic subunit ...   609   e-172
ref|YP_393654.1|  acetolactate synthase 3 catalytic subunit ...   609   e-172
ref|YP_539126.2|  acetolactate synthase 3 catalytic subunit ...   609   e-172
ref|NP_308108.2|  acetolactate synthase 3 catalytic subunit ...   609   e-172
ref|YP_309114.1|  acetolactate synthase 3 catalytic subunit ...   609   e-172
ref|ZP_00727763.1|  COG0028: Thiamine pyrophosphate-requirin...   608   e-172
ref|ZP_01482559.1|  hypothetical protein VchoR_02001517 [Vib...   608   e-172
ref|NP_706030.3|  acetolactate synthase 3 catalytic subunit ...   607   e-172
ref|YP_001738428.1|  acetolactate synthase, large subunit, b...   607   e-172
ref|YP_001093901.1|  acetolactate synthase 3 catalytic subun...   607   e-172
ref|ZP_02348804.1|  acetolactate synthase 3 catalytic subuni...   606   e-171
ref|ZP_02566175.1|  acetolactate synthase 3 catalytic subuni...   606   e-171
ref|YP_263824.1|  acetolactate synthase 3 catalytic subunit ...   606   e-171
ref|NP_070548.1|  acetolactate synthase 3 catalytic subunit ...   606   e-171
ref|ZP_02653812.1|  acetolactate synthase 3 catalytic subuni...   605   e-171
ref|NP_454728.1|  acetolactate synthase 3 catalytic subunit ...   605   e-171
ref|ZP_02341028.1|  acetolactate synthase 3 catalytic subuni...   605   e-171
ref|YP_066505.1|  acetolactate synthase isozyme III, large s...   605   e-171
ref|ZP_02676134.1|  acetolactate synthase 3 catalytic subuni...   605   e-171
ref|ZP_02698236.1|  acetolactate synthase 3 catalytic subuni...   605   e-171
ref|ZP_02344448.1|  acetolactate synthase 3 catalytic subuni...   604   e-171
ref|YP_579789.1|  acetolactate synthase 3 catalytic subunit ...   604   e-171
ref|NP_660569.1|  acetolactate synthase large subunit [Buchn...   604   e-171
ref|ZP_02702672.1|  acetolactate synthase 3 catalytic subuni...   604   e-171
ref|ZP_02647746.1|  acetolactate synthase 3 catalytic subuni...   604   e-171
ref|ZP_02562647.1|  acetolactate synthase 3 catalytic subuni...   603   e-171
ref|NP_228358.1|  acetolactate synthase, large subunit [Ther...   603   e-171
ref|YP_215100.2|  acetolactate synthase 3 catalytic subunit ...   603   e-170
ref|ZP_02684173.1|  acetolactate synthase 3 catalytic subuni...   603   e-170
ref|XP_503660.1|  hypothetical protein [Yarrowia lipolytica]...   602   e-170
ref|YP_149463.1|  acetolactate synthase 3 catalytic subunit ...   602   e-170
ref|XP_001160228.1|  PREDICTED: 2-hydroxyphytanoyl-CoA lyase...   602   e-170
ref|YP_001571876.1|  hypothetical protein SARI_02887 [Salmon...   601   e-170
ref|ZP_02902899.1|  acetolactate synthase, large subunit, is...   601   e-170
emb|CAJ43227.1|  acetolactate synthase large subunit [Buchne...   601   e-170
ref|ZP_00740942.1|  Acetolactate synthase large subunit [Bac...   601   e-170
ref|YP_001661679.1|  acetolactate synthase, large subunit, b...   600   e-170
gb|ABF02354.1|  acetolactate synthase isozyme III large subu...   600   e-170
gb|AAD28737.1|AF118061_1  acetohydroxyacid synthase large su...   600   e-169
ref|XP_001213936.1|  conserved hypothetical protein [Aspergi...   600   e-169
ref|NP_240056.1|  acetolactate synthase large subunit [Buchn...   600   e-169
ref|NP_987770.1|  acetolactate synthase catalytic subunit [M...   600   e-169
ref|XP_001398049.1|  hypothetical protein An16g07490 [Asperg...   599   e-169
ref|ZP_02585109.1|  acetolactate synthase 3 catalytic subuni...   599   e-169
ref|YP_001586422.1|  hypothetical protein SPAB_00147 [Salmon...   599   e-169
ref|YP_001466735.1|  acetolactate synthase, large subunit, b...   599   e-169
ref|ZP_03902833.1|  acetolactate synthase, large subunit [De...   599   e-169
ref|YP_001344340.1|  acetolactate synthase, large subunit, b...   598   e-169
ref|YP_001211077.1|  thiamine pyrophosphate-requiring enzyme...   598   e-169
ref|ZP_02539902.1|  acetolactate synthase 3 catalytic subuni...   598   e-169
ref|NP_844268.1|  acetolactate synthase 3 catalytic subunit ...   598   e-169
ref|YP_036023.1|  acetolactate synthase 3 catalytic subunit ...   598   e-169
ref|YP_001548292.1|  acetolactate synthase, large subunit, b...   597   e-169
ref|ZP_02577817.1|  acetolactate synthase 3 catalytic subuni...   597   e-169
ref|ZP_02592242.1|  acetolactate synthase 3 catalytic subuni...   597   e-169
ref|YP_001644574.1|  acetolactate synthase, large subunit, b...   597   e-169
gb|AAX64019.1|  acetolactate synthase III, valine sensitive,...   595   e-168
ref|YP_001030046.1|  hypothetical protein Mlab_0605 [Methano...   595   e-168
ref|ZP_02521721.1|  acetolactate synthase 3 catalytic subuni...   595   e-168
ref|ZP_01695377.1|  acetolactate synthase, large subunit, bi...   595   e-168
ref|NP_831551.1|  acetolactate synthase 3 catalytic subunit ...   595   e-168
ref|XP_001660326.1|  2-hydroxyphytanoyl-coa lyase [Aedes aeg...   595   e-168
ref|XP_001649370.1|  2-hydroxyphytanoyl-coa lyase [Aedes aeg...   594   e-168
ref|YP_001097475.1|  acetolactate synthase catalytic subunit...   594   e-168
ref|YP_001664029.1|  acetolactate synthase, large subunit, b...   594   e-168
ref|ZP_01868427.1|  acetolactate synthase III large subunit ...   593   e-168
ref|YP_001359127.1|  acetolactate synthase, large subunit [S...   593   e-167
ref|YP_001490085.1|  acetolactate synthase, large subunit [A...   592   e-167
ref|YP_001406720.1|  acetolactate synthase, large subunit, b...   592   e-167
ref|XP_311576.3|  AGAP010368-PA [Anopheles gambiae str. PEST...   592   e-167
ref|YP_001324047.1|  acetolactate synthase catalytic subunit...   592   e-167
ref|YP_517599.1|  hypothetical protein DSY1366 [Desulfitobac...   592   e-167
ref|XP_747326.1|  2-hydroxyphytanoyl-CoA lyase [Aspergillus ...   592   e-167
ref|YP_842552.1|  acetolactate synthase 3 catalytic subunit ...   591   e-167
ref|XP_001547987.1|  hypothetical protein BC1G_13678 [Botryo...   591   e-167
ref|YP_001211080.1|  thiamine pyrophosphate-requiring enzyme...   591   e-167
ref|XP_001262067.1|  2-hydroxyphytanoyl-CoA lyase, putative ...   591   e-167
ref|YP_001273798.1|  acetolactate synthase catalytic subunit...   590   e-166
ref|YP_401831.1|  acetolactate synthase 3 catalytic subunit ...   590   e-166
ref|ZP_01311443.1|  acetolactate synthase, large subunit, bi...   589   e-166
ref|ZP_00236615.1|  acetolactate synthase, large subunit, bi...   588   e-166
gb|EEH46455.1|  2-hydroxyacyl-CoA lyase [Paracoccidioides br...   588   e-166
ref|NP_998250.1|  2-hydroxyacyl-CoA lyase 1 [Danio rerio] >g...   588   e-166
ref|XP_001276631.1|  2-hydroxyphytanoyl-CoA lyase, putative ...   588   e-166
ref|YP_001324878.1|  acetolactate synthase catalytic subunit...   588   e-166
Sequences not found previously or not previously below threshold:

ref|YP_944713.1|  acetolactate synthase, large subunit, bios...   625   e-177
ref|YP_001906687.1|  Acetolactate synthase isozyme III large...   623   e-176
ref|ZP_01116331.1|  acetolactate synthase III large subunit ...   620   e-176
emb|CAJ72436.1|  strongly similar to acetohydroxy acid synth...   619   e-175
ref|YP_927893.1|  acetolactate synthase 3 catalytic subunit ...   619   e-175
ref|YP_001674604.1|  acetolactate synthase, large subunit, b...   617   e-175
ref|ZP_02159491.1|  acetolactate synthase III large subunit ...   617   e-175
gb|ABO32786.1|  IlvI [Xenorhabdus nematophila]                    616   e-174
ref|YP_001501768.1|  acetolactate synthase, large subunit, b...   614   e-174
ref|YP_001111658.1|  acetolactate synthase, large subunit, b...   614   e-174
ref|ZP_01219928.1|  acetolactate synthase III large subunit ...   613   e-174
ref|YP_754808.1|  acetolactate synthase large subunit [Syntr...   613   e-173
ref|YP_001175362.1|  acetolactate synthase 3 catalytic subun...   613   e-173
ref|YP_001474401.1|  acetolactate synthase, large subunit, b...   613   e-173
ref|YP_001554918.1|  acetolactate synthase, large subunit, b...   613   e-173
sp|Q9RQ65|ILVI_BUCSC  Acetolactate synthase large subunit (A...   613   e-173
ref|YP_733881.1|  acetolactate synthase 3 catalytic subunit ...   613   e-173
ref|YP_001050748.1|  acetolactate synthase 3 catalytic subun...   613   e-173
ref|YP_737879.1|  acetolactate synthase 3 catalytic subunit ...   612   e-173
ref|YP_001366575.1|  acetolactate synthase, large subunit, b...   612   e-173
ref|YP_869904.1|  acetolactate synthase 3 catalytic subunit ...   612   e-173
ref|YP_128659.1|  acetolactate synthase 3 catalytic subunit ...   612   e-173
ref|YP_001333772.1|  acetolactate synthase III large subunit...   611   e-173
gb|ABU62921.1|  catalytic subunit protein [Klebsiella pneumo...   611   e-173
ref|ZP_01706659.1|  acetolactate synthase, large subunit, bi...   610   e-173
ref|YP_963262.1|  acetolactate synthase 3 catalytic subunit ...   610   e-173
ref|YP_001183658.1|  acetolactate synthase 3 catalytic subun...   610   e-173
ref|YP_001454821.1|  hypothetical protein CKO_03301 [Citroba...   610   e-172
gb|EDN75307.1|  acetolactate synthase [Mannheimia haemolytic...   610   e-172
ref|NP_717875.1|  acetolactate synthase 3 catalytic subunit ...   610   e-172
ref|NP_952960.1|  acetolactate synthase, large subunit, bios...   609   e-172
gb|AAF13795.1|AF129503_2  acetohydroxy acid synthase large s...   608   e-172
ref|YP_001760334.1|  acetolactate synthase, large subunit, b...   608   e-172
ref|YP_384221.1|  Acetolactate synthase, large subunit, bios...   607   e-172
ref|NP_632694.1|  acetolactate synthase 3 catalytic subunit ...   607   e-172
gb|ABU63574.1|  AHAS catalytic subunit [Klebsiella pneumoniae]    607   e-172
ref|YP_563127.1|  acetolactate synthase 3 catalytic subunit ...   607   e-172
ref|ZP_01898340.1|  putative acetolactate synthase III, larg...   606   e-171
ref|YP_114688.1|  acetolactate synthase, large subunit, bios...   606   e-171
ref|NP_245807.1|  acetolactate synthase 3 catalytic subunit ...   606   e-171
ref|YP_436992.1|  acetolactate synthase 3 catalytic subunit ...   606   e-171
ref|NP_906370.1|  acetolactate synthase 3 catalytic subunit ...   605   e-171
ref|NP_618663.1|  acetolactate synthase 3 catalytic subunit ...   605   e-171
gb|AAF13787.1|AF129501_2  acetohydroxy acid synthase large s...   605   e-171
ref|YP_357321.1|  acetolactate synthase, large subunit, bios...   604   e-171
ref|YP_750317.1|  acetolactate synthase 3 catalytic subunit ...   604   e-171
ref|YP_390904.1|  acetolactate synthase, large subunit, bios...   603   e-170
ref|YP_001356279.1|  acetolactate synthase, large subunit [N...   603   e-170
ref|ZP_02462916.1|  acetolactate synthase 3 catalytic subuni...   603   e-170
ref|YP_502706.1|  acetolactate synthase, large subunit, bios...   602   e-170
ref|ZP_02362280.1|  acetolactate synthase 3 catalytic subuni...   602   e-170
ref|YP_001651736.1|  acetolactate synthase large subunit [Ac...   601   e-170
ref|YP_001708120.1|  acetolactate synthase III, large subuni...   601   e-170
ref|YP_565425.1|  acetolactate synthase 3 catalytic subunit ...   601   e-170
ref|ZP_02355077.1|  acetolactate synthase 3 catalytic subuni...   601   e-170
ref|ZP_01613488.1|  acetolactate synthase isozyme III large ...   600   e-170
ref|ZP_01166487.1|  acetolactate synthase large subunit [Oce...   599   e-169
ref|YP_855428.1|  acetolactate synthase, large subunit, bios...   599   e-169
ref|NP_621734.1|  Thiamine pyrophosphate-requiring enzyme [a...   598   e-169
ref|ZP_01188450.1|  Acetolactate synthase, large subunit, bi...   597   e-169
ref|ZP_01770640.1|  acetolactate synthase, large subunit, bi...   597   e-169
ref|YP_107818.1|  acetolactate synthase 3 catalytic subunit ...   597   e-169
ref|YP_103451.1|  acetolactate synthase 3 catalytic subunit ...   597   e-169
gb|EDK58417.1|  acetolactate synthase, large subunit, biosyn...   597   e-169
ref|YP_001053432.1|  acetolactate synthase 3 catalytic subun...   597   e-169
ref|YP_303782.1|  acetolactate synthase 3 catalytic subunit ...   597   e-169
ref|YP_295170.1|  acetolactate synthase 3 catalytic subunit ...   597   e-169
ref|YP_441599.1|  acetolactate synthase 3 catalytic subunit ...   597   e-168
ref|YP_269926.1|  acetolactate synthase III, large subunit, ...   597   e-168
ref|YP_001039106.1|  acetolactate synthase, large subunit, b...   596   e-168
ref|NP_900256.1|  acetolactate synthase isozyme III, large s...   596   e-168
ref|YP_902220.1|  acetolactate synthase, large subunit, bios...   596   e-168
ref|YP_001143127.1|  acetolactate synthase isozyme III, larg...   596   e-168
ref|YP_583066.1|  acetolactate synthase 3 catalytic subunit ...   596   e-168
ref|YP_388660.1|  acetolactate synthase, large subunit, bios...   595   e-168
ref|YP_359375.1|  acetolactate synthase, large subunit, bios...   595   e-168
ref|NP_520198.1|  acetolactate synthase 3 catalytic subunit ...   595   e-168
ref|YP_001350734.1|  acetolactate synthase, large subunit, b...   595   e-168
ref|YP_001791923.1|  acetolactate synthase, large subunit, b...   594   e-168
ref|YP_001899794.1|  acetolactate synthase, large subunit, b...   594   e-168
ref|ZP_01774694.1|  acetolactate synthase, large subunit, bi...   594   e-168
ref|YP_967136.1|  acetolactate synthase, large subunit, bios...   594   e-168
gb|EAY58027.1|  Thiamine pyrophosphate-requiring enzyme [Lep...   594   e-168
ref|YP_010595.1|  acetolactate synthase, large subunit, bios...   594   e-168
ref|ZP_02009737.1|  acetolactate synthase, large subunit, bi...   594   e-168
ref|YP_047618.1|  acetolactate synthase 3 catalytic subunit ...   593   e-167
ref|YP_001111655.1|  acetolactate synthase, large subunit, b...   593   e-167
ref|YP_934657.1|  acetolactate synthase [Azoarcus sp. BH72] ...   593   e-167
ref|ZP_01307827.1|  acetolactate synthase, large subunit, bi...   593   e-167
ref|YP_725545.1|  acetolactate synthase 3 catalytic subunit ...   593   e-167
ref|YP_341947.1|  acetolactate synthase isozyme III large su...   592   e-167
ref|YP_001330883.1|  acetolactate synthase catalytic subunit...   592   e-167
ref|ZP_03823351.1|  acetolactate synthase III, large subunit...   592   e-167
ref|YP_350516.1|  acetolactate synthase 3 catalytic subunit ...   592   e-167
ref|ZP_01323079.1|  hypothetical protein BpseP_03003157 [Bur...   592   e-167
ref|ZP_00135474.1|  COG0028: Thiamine pyrophosphate-requirin...   592   e-167
ref|ZP_00440969.1|  COG0028: Thiamine pyrophosphate-requirin...   592   e-167
ref|YP_001894967.1|  acetolactate synthase, large subunit, b...   592   e-167
ref|YP_692201.1|  acetolactate synthase 3 catalytic subunit ...   592   e-167
ref|ZP_01521731.1|  acetolactate synthase, large subunit, bi...   592   e-167
ref|ZP_01617210.1|  acetolactate synthase III large subunit ...   592   e-167
ref|ZP_00943336.1|  Acetolactate synthase large subunit [Ral...   591   e-167
ref|YP_001568611.1|  acetolactate synthase, large subunit, b...   591   e-167
ref|NP_253384.1|  acetolactate synthase 3 catalytic subunit ...   591   e-167
gb|ABL97373.1|  acetolactate synthase III large subunit [unc...   591   e-167
ref|ZP_01109309.1|  acetolactate synthase III large subunit ...   591   e-167
ref|ZP_00420009.1|  Acetolactate synthase, large subunit, bi...   590   e-167
ref|ZP_01132006.1|  acetolactate synthase isozyme III large ...   590   e-166
ref|YP_528016.1|  acetolactate synthase 3 catalytic subunit ...   590   e-166
ref|ZP_03905694.1|  acetolactate synthase, large subunit [De...   589   e-166
gb|ABL09941.1|  IlvI [Pseudomonas aeruginosa] >gi|118640848|...   589   e-166
ref|YP_463020.1|  acetolactate synthase large subunit [Syntr...   588   e-166
ref|YP_002794161.1|  IlvI [Laribacter hongkongensis HLHK9] >...   588   e-166
ref|ZP_01915784.1|  acetolactate synthase large subunit [Lim...   588   e-166
ref|YP_001404604.1|  acetolactate synthase, large subunit, b...   588   e-166
>ref|NP_010895.1| hypothetical protein with low sequence identity to Pdc1p; Yel020cp
           [Saccharomyces cerevisiae]
 sp|P39994|YEC0_YEAST Putative 2-hydroxyacyl-CoA lyase
 gb|AAB64497.1| Yel020cp [Saccharomyces cerevisiae]
          Length = 560

 Score =  749 bits (1935), Expect = 0.0,   Method: Composition-based stats.
 Identities = 560/560 (100%), Positives = 560/560 (100%)

Query: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG 60
           MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG
Sbjct: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG 60

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
           YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL
Sbjct: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120

Query: 121 SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
           SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP
Sbjct: 121 SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
           MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP
Sbjct: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP
Sbjct: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR 360
           ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR
Sbjct: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR 360

Query: 361 KEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT 420
           KEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT
Sbjct: 361 KEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT 420

Query: 421 MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE 480
           MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE
Sbjct: 421 MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE 480

Query: 481 KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV 540
           KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV
Sbjct: 481 KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV 540

Query: 541 IIEPGEQKQIAFAWQNKPRL 560
           IIEPGEQKQIAFAWQNKPRL
Sbjct: 541 IIEPGEQKQIAFAWQNKPRL 560
>gb|EDN62949.1| conserved protein [Saccharomyces cerevisiae YJM789]
          Length = 560

 Score =  748 bits (1932), Expect = 0.0,   Method: Composition-based stats.
 Identities = 557/560 (99%), Positives = 558/560 (99%)

Query: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG 60
           MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG
Sbjct: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYG 60

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
           YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL
Sbjct: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120

Query: 121 SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
           SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP
Sbjct: 121 SPFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
           MILTPN+CGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP
Sbjct: 181 MILTPNLCGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFG SPKWNSESIFIQFDSNP
Sbjct: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGASPKWNSESIFIQFDSNP 300

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR 360
           ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR
Sbjct: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLLR 360

Query: 361 KEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT 420
           KEKTRG QLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT
Sbjct: 361 KEKTRGTQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT 420

Query: 421 MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE 480
           MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE
Sbjct: 421 MGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHGE 480

Query: 481 KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV 540
           KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV
Sbjct: 481 KDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSVINV 540

Query: 541 IIEPGEQKQIAFAWQNKPRL 560
           IIEPGEQKQIAFAWQNKPRL
Sbjct: 541 IIEPGEQKQIAFAWQNKPRL 560
>ref|XP_001160528.1| PREDICTED: 2-hydroxyphytanoyl-CoA lyase isoform 8 [Pan troglodytes]
          Length = 578

 Score =  662 bits (1710), Expect = 0.0,   Method: Composition-based stats.
 Identities = 214/579 (36%), Positives = 319/579 (55%), Gaps = 33/579 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY
Sbjct: 13  QVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGY 72

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV    
Sbjct: 73  LTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACR 132

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   + 
Sbjct: 133 LYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYME 188

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
             ++P I   + S +     +I   K   ++I  G         I++LV  + LPFLPTP
Sbjct: 189 RCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTP 248

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   
Sbjct: 249 MGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICA 308

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTR 357
           E LG+N       +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+  
Sbjct: 309 EELGNN---VKPTVTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAA 363

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT
Sbjct: 364 SKELASKKSLPMNYYTVFYHIQEQLPRD-CFVVSEGANTMDIGRTVLQNYLPRHRLDAGT 422

Query: 418 NATMGIGLGYALACKASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A      +      ++ ++GDSAFGFS ME+ET  R  L ++++V+NN
Sbjct: 423 FGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNN 482

Query: 474 SGIYHG-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G            +D    +PP  L  N  Y+ V    G   +FV T  EL +  
Sbjct: 483 NGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSL 542

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           +Q++       + S+INV+IEP   +K   F W  +  +
Sbjct: 543 RQSLA---DTTKPSLINVMIEPQATRKAQDFHWLTRSNM 578
>gb|AAF28957.1|AF161397_1 HSPC279 [Homo sapiens]
          Length = 581

 Score =  660 bits (1705), Expect = 0.0,   Method: Composition-based stats.
 Identities = 213/579 (36%), Positives = 319/579 (55%), Gaps = 33/579 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY
Sbjct: 16  QVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGY 75

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV    
Sbjct: 76  LTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACR 135

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   + 
Sbjct: 136 LYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYME 191

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
             ++P I   + S +     +I   K   ++I  G         I++LV  + LPFLPTP
Sbjct: 192 RCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTP 251

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   
Sbjct: 252 MGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICA 311

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTR 357
           E LG+N       +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+  
Sbjct: 312 EELGNN---VKPAVTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAA 366

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT
Sbjct: 367 SKELASKKSLPMNYYTVFYHVQEQLPRD-CFVVSEGANTMDIGRTVLQNYLPRHRLDAGT 425

Query: 418 NATMGIGLGYALACKASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A      +      ++ ++GDSAFGFS ME+ET  R  L ++++V+NN
Sbjct: 426 FGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNN 485

Query: 474 SGIYHG-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G            +D    +PP  L  N  Y+ V    G   +FV T  EL +  
Sbjct: 486 NGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSL 545

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           +Q++       + S+IN++IEP   +K   F W  +  +
Sbjct: 546 RQSLA---DTTKPSLINIMIEPQATRKAQDFHWLTRSNM 581
>ref|XP_534256.2| PREDICTED: similar to 2-hydroxyphytanoyl-CoA lyase (2-HPCL) [Canis
           familiaris]
          Length = 667

 Score =  660 bits (1704), Expect = 0.0,   Method: Composition-based stats.
 Identities = 217/579 (37%), Positives = 320/579 (55%), Gaps = 33/579 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ VFGIVGIP+ ++A      GI+++  RNEQAA YAASA GY
Sbjct: 102 KVSGAEVIAQALKTQDVEYVFGIVGIPVTEIAVAAQKLGIRYVGMRNEQAACYAASAVGY 161

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPL+VI GSS +     G FQE  QV    
Sbjct: 162 LTGRPGVCLVVSGPGLIHALGGMANANVNCWPLIVIGGSSERRQETMGAFQEFPQVEACR 221

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +  + I  I +KA+   I G  G  Y+D+PADF+ +    + N  +   + 
Sbjct: 222 LYCKFSARPSSIETIPSIIEKAVRSSIYGRPGPCYVDIPADFVNF----QVNVNSIKYVE 277

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
             L P +   + S +     ++   K   ++I  G    +    IR+LV    LPFLPTP
Sbjct: 278 CCLPPPVSMAETSAVYMAASVLRNAKRPLLIIGKGAAYSRAEEAIRKLVGQCKLPFLPTP 337

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD+ P  VS+ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   
Sbjct: 338 MGKGVVPDNHPNCVSAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQIDICA 397

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTR 357
           E LG+N       +S+ GDI      L+E+  +  + W+Y   S   Q +REK++ N+  
Sbjct: 398 EELGNN---VKPAVSLLGDINAVTKQLLEQFDK--TPWQYPPESSWWQTLREKMESNEAA 452

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT
Sbjct: 453 SKELASQKSLPMNYYTVFYQVQEQLPRD-CFVVSEGANTMDIGRTVIQNYLPRHRLDAGT 511

Query: 418 NATMGIGLGYALACKAS----HPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A        +P   V+ ++GDSAFGFS ME+ET  R  L +V++V+NN
Sbjct: 512 FGTMGVGLGFAIAAAIVARDRNPGKRVICVEGDSAFGFSGMEVETICRYNLPIVLLVVNN 571

Query: 474 SGIYHG-----EKDI--EGD----LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G      K++   GD     PP  L  N  Y+ V    G   +FV T  EL +  
Sbjct: 572 NGIYQGFDADSWKEMLKFGDATEVAPPVCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSL 631

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           ++++       + S+IN++IEP   +K   F W  +  +
Sbjct: 632 RESLA---DTTKPSLINIMIEPQATRKAQDFHWLTRSNM 667
>emb|CAB60200.1| 2-hydroxyphytanoyl-CoA lyase [Homo sapiens]
          Length = 578

 Score =  660 bits (1703), Expect = 0.0,   Method: Composition-based stats.
 Identities = 213/579 (36%), Positives = 319/579 (55%), Gaps = 33/579 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY
Sbjct: 13  QVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGY 72

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV    
Sbjct: 73  LTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACR 132

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   + 
Sbjct: 133 LYTKFSARXSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYME 188

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
             ++P I   + S +     +I   K   ++I  G         I++LV  + LPFLPTP
Sbjct: 189 RCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTP 248

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   
Sbjct: 249 MGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICA 308

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTR 357
           E LG+N       +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+  
Sbjct: 309 EELGNN---VKPAVTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAA 363

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT
Sbjct: 364 SKELASKKSLPMNYYTVFYHVQEQLPRD-CFVVSEGANTMDIGRTVLQNYLPRHRLDAGT 422

Query: 418 NATMGIGLGYALACKASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A      +      ++ ++GDSAFGFS ME+ET  R  L ++++V+NN
Sbjct: 423 FGTMGVGLGFAIAAAVVAKDRSPGHWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNN 482

Query: 474 SGIYHG-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G            +D    +PP  L  N  Y+ V    G   +FV T  EL +  
Sbjct: 483 NGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSL 542

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           +Q++       + S+IN++IEP   +K   F W  +  +
Sbjct: 543 EQSLA---DTTKPSLINIMIEPQATRKAQDFHWLTRSNM 578
>ref|NP_036392.2| 2-hydroxyphytanoyl-CoA lyase [Homo sapiens]
 sp|Q9UJ83|HACL1_HUMAN 2-hydroxyacyl-CoA lyase 1 (2-hydroxyphytanoyl-CoA lyase) (2-HPCL)
           (Phytanoyl-CoA 2-hydroxylase 2)
 gb|AAH01627.1| 2-hydroxyacyl-CoA lyase 1 [Homo sapiens]
 gb|EAW64251.1| phytanoyl-CoA 2-hydroxylase 2, isoform CRA_a [Homo sapiens]
 gb|ABM86484.1| 2-hydroxyacyl-CoA lyase 1 [synthetic construct]
 gb|ABW03818.1| 2-hydroxyacyl-CoA lyase 1 [synthetic construct]
          Length = 578

 Score =  659 bits (1702), Expect = 0.0,   Method: Composition-based stats.
 Identities = 213/579 (36%), Positives = 319/579 (55%), Gaps = 33/579 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY
Sbjct: 13  QVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGY 72

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV    
Sbjct: 73  LTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACR 132

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   + 
Sbjct: 133 LYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYME 188

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
             ++P I   + S +     +I   K   ++I  G         I++LV  + LPFLPTP
Sbjct: 189 RCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTP 248

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   
Sbjct: 249 MGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICA 308

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTR 357
           E LG+N       +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+  
Sbjct: 309 EELGNN---VKPAVTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAA 363

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT
Sbjct: 364 SKELASKKSLPMNYYTVFYHVQEQLPRD-CFVVSEGANTMDIGRTVLQNYLPRHRLDAGT 422

Query: 418 NATMGIGLGYALACKASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A      +      ++ ++GDSAFGFS ME+ET  R  L ++++V+NN
Sbjct: 423 FGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNN 482

Query: 474 SGIYHG-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G            +D    +PP  L  N  Y+ V    G   +FV T  EL +  
Sbjct: 483 NGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSL 542

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           +Q++       + S+IN++IEP   +K   F W  +  +
Sbjct: 543 RQSLA---DTTKPSLINIMIEPQATRKAQDFHWLTRSNM 578
>ref|XP_418737.2| PREDICTED: hypothetical protein [Gallus gallus]
          Length = 568

 Score =  655 bits (1690), Expect = 0.0,   Method: Composition-based stats.
 Identities = 235/579 (40%), Positives = 330/579 (56%), Gaps = 33/579 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  Q  A+ L+   I+ +FG+VGIPI ++A    A GIK+I  RNEQAA YAASA GY
Sbjct: 3   ELSGAQLIAEALRAQNIEYMFGVVGIPITEVAVAAQAAGIKYIGMRNEQAACYAASAVGY 62

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPG +H L G+ N+  N WPL+VI GSS ++    G FQE  QV    
Sbjct: 63  LTGRPGVCLVVSGPGFLHTLGGMANANMNCWPLIVIGGSSDRNQETMGAFQEFPQVEAAR 122

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + K + + +  + I  + +KA+   I G  G  YID+P DF+     L+ N  +   + 
Sbjct: 123 LYNKLSVRPSSLEAIPAVIEKAVRTSIYGRPGSCYIDIPGDFVN----LQVNKSSVKYVE 178

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLP 238
               P I   + S + + V +I   K    L++IGKGA  +  E  IR+LV+   LPFLP
Sbjct: 179 CCPPPPISTAEHSAVSEAVSIIAHAK--QPLLIIGKGAAYSRAENNIRKLVDLSGLPFLP 236

Query: 239 TPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDS 298
           TPMAKG+VPD+ P  V++ARS AL  AD++++LGARLNWILHFG  P++  +   IQ D 
Sbjct: 237 TPMAKGVVPDNHPNCVAAARSTALLHADVIILLGARLNWILHFGLPPRFRQDVKVIQIDI 296

Query: 299 NPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWK-YSGVKQEIREKIQLNQTR 357
             E +G NNV P A L   GDI      L+EE +++   +   S   +++REK+  N+ R
Sbjct: 297 CAEEMG-NNVRPAAML--LGDINAVTKQLLEEFSKRPLKYPSNSEWWKKLREKMLNNEER 353

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  +R L+     ILV+EGANTMDI R   P   PR+RLDAGT
Sbjct: 354 SKDLALQKSLPMNYYTVFHHIRELVPKD-CILVSEGANTMDIGRTMLPNYHPRQRLDAGT 412

Query: 418 NATMGIGLGYALACKASH----PELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A         PE  V+ I+GDSAFGFS ME+ET  R  L ++I+V+NN
Sbjct: 413 FGTMGVGLGFAIAAALVAKDRTPEKRVICIEGDSAFGFSGMEVETICRYNLPILIIVVNN 472

Query: 474 SGIYHG-------EKDIEGDL----PPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G       E    GD     PP +L  N  Y+ +    G   +FVNT  EL    
Sbjct: 473 NGIYTGLDAGSWKEMLQYGDPVTSVPPVSLLPNAHYEEIMSAFGGKGYFVNTPEELQNAV 532

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           + ++     K+  S+INV+I+P  E+K+  F W  +  L
Sbjct: 533 KASLA---DKQTPSLINVMIDPQSERKKQEFPWLTRSNL 568
>gb|EDL24815.1| 2-hydroxyacyl-CoA lyase 1 [Mus musculus]
          Length = 587

 Score =  654 bits (1689), Expect = 0.0,   Method: Composition-based stats.
 Identities = 214/579 (36%), Positives = 319/579 (55%), Gaps = 33/579 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FG+VGIP+ ++A      GIK+I  RNEQAA YAASA GY
Sbjct: 22  QVSGAKVIAQALKTQDVEYMFGVVGIPVTEIALAAQELGIKYIGMRNEQAACYAASAVGY 81

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPL+VI GSS ++    G FQE  QV    
Sbjct: 82  LTGRPGVCLVVSGPGLIHALGGMANANMNCWPLIVIGGSSERNQEAMGAFQEFPQVEACR 141

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +  + I  I +KA+   I G  G  YID+PADF+     L+ N  +     
Sbjct: 142 LYTKFSARPSTIELIPFIIEKAVRSSIYGRPGACYIDIPADFVT----LQANVTSIKYKE 197

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLP 238
             + P +   + S +     ++   K    L++IGKGA  +  E  IR+LV   +LPFLP
Sbjct: 198 CCMPPPVSMAETSAVCAAASVLRDAK--QPLLIIGKGAAYSHAEDSIRKLVEQCSLPFLP 255

Query: 239 TPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDS 298
           TPM KG+VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++ ++  FIQ D 
Sbjct: 256 TPMGKGVVPDNHPNCVGAARSRALQSADVIVLFGARLNWILHFGLPPRYQADVKFIQIDI 315

Query: 299 NPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQD-SCWKYSGVKQEIREKIQLNQTR 357
             E LG+N       + + GDI      L+E+  +    C   S   + +REK++ N+  
Sbjct: 316 CAEELGNN---VRPSVILLGDIDAVSKQLLEQFDKTPWQCPPDSQWWKTLREKMKSNEAI 372

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  ++  +    + +V+EGANTMDI R       PR RLDAG+
Sbjct: 373 SKELASQKSLPMNYYTVFYHVQEQLPRD-SFIVSEGANTMDIGRTMLQNCLPRHRLDAGS 431

Query: 418 NATMGIGLGYALACKASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A      +      V+ ++GDSAFGFS ME+ET  R  L ++++V+NN
Sbjct: 432 FGTMGVGLGFAIAAALVAKDRSPGQRVICVEGDSAFGFSGMEVETICRYNLPIILLVVNN 491

Query: 474 SGIYHG-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G            ++    +PP  L  N  Y+ V    G   +FV T  EL    
Sbjct: 492 NGIYQGFDADTWEKMLHFQEAATTVPPMCLLPNSHYEQVMTAFGGKGYFVRTPEELQHSL 551

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           +QA+Q      +  ++N++IEP   +K   F W  +  +
Sbjct: 552 RQALQ---DTSKPCLLNIMIEPQSTRKAQDFHWLTRSNM 587
>ref|NP_445945.1| 2-hydroxyacyl-CoA lyase 1 [Rattus norvegicus]
 sp|Q8CHM7|HACL1_RAT 2-hydroxyacyl-CoA lyase 1 (2-hydroxyphytanoyl-CoA lyase) (2-HPCL)
           (Phytanoyl-CoA 2-hydroxylase 2)
 emb|CAD56981.1| 2-hydroxyphytanoyl-CoA lyase [Rattus norvegicus]
 gb|AAH78697.1| Phytanoyl-CoA 2-hydroxylase 2 [Rattus norvegicus]
 gb|EDL88941.1| phytanoyl-CoA 2-hydroxylase 2 [Rattus norvegicus]
          Length = 581

 Score =  654 bits (1689), Expect = 0.0,   Method: Composition-based stats.
 Identities = 217/581 (37%), Positives = 322/581 (55%), Gaps = 37/581 (6%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FG+VGIP+ ++A      GIK+I  RNEQAA YAASA GY
Sbjct: 16  QVSGAKVIAQALKTQDVEYMFGVVGIPVTEIALAAQELGIKYIGMRNEQAACYAASAVGY 75

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPL+VI GSS ++    G FQE  QV    
Sbjct: 76  LTGRPGVCLVVSGPGLIHALGGMANANMNCWPLIVIGGSSERNQEAMGAFQEFPQVEACR 135

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +   +I  + +KA+   I G  G  YIDVPAD +     L+ +  +     
Sbjct: 136 LYSKFSARPSSIQHIPFVIEKAVRSSIYGRPGACYIDVPADLVT----LQESTTSIKYKE 191

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLP 238
             + P +   + S ++    ++   K    L++IGKGA  +  E  IR+LV   NLPFLP
Sbjct: 192 CCMPPPLSLAETSAVRAAASVLRSAK--QPLLIIGKGAAYSHAEDSIRKLVELCNLPFLP 249

Query: 239 TPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDS 298
           TPM KG+VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++ ++  FIQ D 
Sbjct: 250 TPMGKGVVPDNHPNCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQADVKFIQIDI 309

Query: 299 NPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQ 355
             E LG+N       +++ GD+      L+E+  +  + W+Y   S   + +REK + N+
Sbjct: 310 CAEELGNN---VRPSVTLLGDVNAVSKQLLEQFVK--NPWQYPTDSKWWETLREKRKNNE 364

Query: 356 TRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDA 415
                    +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDA
Sbjct: 365 AVSKELASKKSLPMNYYTVFYHVQEQLPR-NCFIVSEGANTMDIGRTVLQNYLPRHRLDA 423

Query: 416 GTNATMGIGLGYALACKASH----PELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVM 471
           G+  TMG+GLG+A+A         P   V+ ++GDSAFGFS ME+ET  R  L ++I+V+
Sbjct: 424 GSFGTMGVGLGFAIAAAVVAKERSPGQRVICVEGDSAFGFSGMEVETICRYNLPIIILVV 483

Query: 472 NNSGIYHG-EKDIEGD----------LPPTALSKNCRYDLVGKGLGANDFFVNTISELSR 520
           NN+GIY G + D  G           +PP  L  N  Y+ V    G   +FV T  EL  
Sbjct: 484 NNNGIYQGFDADTWGKILNFQGTATTIPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQD 543

Query: 521 CFQQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
             +QA+   +   +  +IN++IEP   +K   F W  +  +
Sbjct: 544 SLRQAL---KDTSKPCLINIMIEPQSTRKAQDFHWLTRSNI 581
>ref|NP_064359.2| 2-hydroxyacyl-CoA lyase 1 [Mus musculus]
 sp|Q9QXE0|HACL1_MOUSE 2-hydroxyacyl-CoA lyase 1 (2-hydroxyphytanoyl-CoA lyase) (2-HPCL)
           (Phytanoyl-CoA 2-hydroxylase 2)
 dbj|BAB24085.1| unnamed protein product [Mus musculus]
 gb|AAH21360.1| 2-hydroxyacyl-CoA lyase 1 [Mus musculus]
 dbj|BAC31032.1| unnamed protein product [Mus musculus]
 dbj|BAC34059.1| unnamed protein product [Mus musculus]
          Length = 581

 Score =  653 bits (1685), Expect = 0.0,   Method: Composition-based stats.
 Identities = 214/579 (36%), Positives = 319/579 (55%), Gaps = 33/579 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FG+VGIP+ ++A      GIK+I  RNEQAA YAASA GY
Sbjct: 16  QVSGAKVIAQALKTQDVEYMFGVVGIPVTEIALAAQELGIKYIGMRNEQAACYAASAVGY 75

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPL+VI GSS ++    G FQE  QV    
Sbjct: 76  LTGRPGVCLVVSGPGLIHALGGMANANMNCWPLIVIGGSSERNQEAMGAFQEFPQVEACR 135

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +  + I  I +KA+   I G  G  YID+PADF+     L+ N  +     
Sbjct: 136 LYTKFSARPSTIELIPFIIEKAVRSSIYGRPGACYIDIPADFVT----LQANVTSIKYKE 191

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLP 238
             + P +   + S +     ++   K    L++IGKGA  +  E  IR+LV   +LPFLP
Sbjct: 192 CCMPPPVSMAETSAVCAAASVLRDAK--QPLLIIGKGAAYSHAEDSIRKLVEQCSLPFLP 249

Query: 239 TPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDS 298
           TPM KG+VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++ ++  FIQ D 
Sbjct: 250 TPMGKGVVPDNHPNCVGAARSRALQSADVIVLFGARLNWILHFGLPPRYQADVKFIQIDI 309

Query: 299 NPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQD-SCWKYSGVKQEIREKIQLNQTR 357
             E LG+N       + + GDI      L+E+  +    C   S   + +REK++ N+  
Sbjct: 310 CAEELGNN---VRPSVILLGDIDAVSKQLLEQFDKTPWQCPPDSQWWKTLREKMKSNEAI 366

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  ++  +    + +V+EGANTMDI R       PR RLDAG+
Sbjct: 367 SKELASQKSLPMNYYTVFYHVQEQLPRD-SFIVSEGANTMDIGRTMLQNCLPRHRLDAGS 425

Query: 418 NATMGIGLGYALACKASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A      +      V+ ++GDSAFGFS ME+ET  R  L ++++V+NN
Sbjct: 426 FGTMGVGLGFAIAAALVAKDRSPGQRVICVEGDSAFGFSGMEVETICRYNLPIILLVVNN 485

Query: 474 SGIYHG-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G            ++    +PP  L  N  Y+ V    G   +FV T  EL    
Sbjct: 486 NGIYQGFDADTWEKMLHFQEAATTVPPMCLLPNSHYEQVMTAFGGKGYFVRTPEELQHSL 545

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           +QA+Q      +  ++N++IEP   +K   F W  +  +
Sbjct: 546 RQALQ---DTSKPCLLNIMIEPQSTRKAQDFHWLTRSNM 581
>emb|CAB65550.1| 2-hydroxyphytanoyl-CoA lyase [Mus musculus]
          Length = 581

 Score =  649 bits (1674), Expect = 0.0,   Method: Composition-based stats.
 Identities = 213/579 (36%), Positives = 319/579 (55%), Gaps = 33/579 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FG+VGIP+ ++A      GIK+I  RNEQAA YAASA GY
Sbjct: 16  QVSGAKVIAQALKTQDVEYMFGVVGIPVTEIALAAQELGIKYIGMRNEQAACYAASAVGY 75

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPL+VI GSS ++    G FQE  QV    
Sbjct: 76  LTGRPGVCLVVSGPGLIHALGGMANANMNCWPLIVIGGSSERNQEAMGAFQEFPQVEACR 135

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +  + I  I +KA+   I G  G  YID+PADF+     L+ N  +     
Sbjct: 136 LYTKFSARPSTIELIPFIIEKAVRSSIYGRPGACYIDIPADFVT----LQANVTSIKYKE 191

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLP 238
             + P +   + S +     ++   K    L++IGKGA  +  E  IR+LV   +LPFLP
Sbjct: 192 CCMPPPVSMAETSAVCAAASVLRDAK--QPLLIIGKGAAYSHAEDSIRKLVEQCSLPFLP 249

Query: 239 TPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDS 298
           TP+ KG+VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++ ++  FIQ D 
Sbjct: 250 TPIGKGVVPDNHPNCVGAARSRALQSADVIVLFGARLNWILHFGLPPRYQADVKFIQIDI 309

Query: 299 NPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQD-SCWKYSGVKQEIREKIQLNQTR 357
             E LG+N       + + GDI      L+E+  +    C   S   + +REK++ N+  
Sbjct: 310 CAEELGNN---VRPSVILLGDIDAVSKQLLEQFDKTPWQCPPDSQWWKTLREKMKSNEAI 366

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  ++  +    + +V+EGANTMDI R       PR RLDAG+
Sbjct: 367 SKELASQKSLPMNYYTVFYHVQEQLPRD-SFIVSEGANTMDIGRTMLQNCLPRHRLDAGS 425

Query: 418 NATMGIGLGYALACKASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A      +      V+ ++GDSAFGFS ME+ET  R  L ++++V+NN
Sbjct: 426 FGTMGVGLGFAIAAALVAKDRSPGQRVICVEGDSAFGFSGMEVETICRYNLPIILLVVNN 485

Query: 474 SGIYHG-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G            ++    +PP  L  N  Y+ V    G   +FV T  EL    
Sbjct: 486 NGIYQGFDADTWEKMLHFQEAATTVPPMCLLPNSHYEQVMTAFGGKGYFVRTPEELQHSL 545

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           +QA+Q      +  ++N++IEP   +K   F W  +  +
Sbjct: 546 RQALQ---DTSKPCLLNIMIEPQSTRKAQDFHWLTRSNM 581
>ref|XP_001160323.1| PREDICTED: 2-hydroxyphytanoyl-CoA lyase isoform 4 [Pan troglodytes]
          Length = 566

 Score =  648 bits (1673), Expect = 0.0,   Method: Composition-based stats.
 Identities = 211/565 (37%), Positives = 313/565 (55%), Gaps = 33/565 (5%)

Query: 16  YGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVLLIVGGP 75
             ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV L+V GP
Sbjct: 15  QDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVCLVVSGP 74

Query: 76  GLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGKLTP-DN 134
           GLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV     + KF+ + +  + 
Sbjct: 75  GLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEA 134

Query: 135 IDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNICGPDPSK 194
           I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   +   ++P I   + S 
Sbjct: 135 IPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMERCMSPPISMAETSA 190

Query: 195 IKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMAKGIVPDSSPLNV 254
           +     +I   K   ++I  G         I++LV  + LPFLPTPM KG+VPD+ P  V
Sbjct: 191 VCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCV 250

Query: 255 SSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDNNVSPGADL 314
            +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   E LG+N       +
Sbjct: 251 GAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELGNN---VKPTV 307

Query: 315 SIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEKTRGAQLNY 371
           ++ G+I      L+EEL +  + W+Y   S   + +REK++ N+         +   +NY
Sbjct: 308 TLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNY 365

Query: 372 NQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGIGLGYALAC 431
             V+  ++  +      +V+EGANTMDI R       PR RLDAGT  TMG+GLG+A+A 
Sbjct: 366 YTVFYHIQEQLPRD-CFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAA 424

Query: 432 KASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHG-------- 479
                +      ++ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY G        
Sbjct: 425 AVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQGFDTDTWKE 484

Query: 480 ---EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETS 536
               +D    +PP  L  N  Y+ V    G   +FV T  EL +  +Q++       + S
Sbjct: 485 MLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLA---DTTKPS 541

Query: 537 VINVIIEP-GEQKQIAFAWQNKPRL 560
           +INV+IEP   +K   F W  +  +
Sbjct: 542 LINVMIEPQATRKAQDFHWLTRSNM 566
>ref|XP_001495031.1| PREDICTED: similar to 2-hydroxyacyl-CoA lyase 1 [Equus caballus]
          Length = 581

 Score =  648 bits (1672), Expect = 0.0,   Method: Composition-based stats.
 Identities = 212/576 (36%), Positives = 318/576 (55%), Gaps = 33/576 (5%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISD 64
             +  AQ L+  G+  +FG+VGIP+ ++A      GI+++  RNEQAA YAAS  GY++D
Sbjct: 19  GAKVIAQALKTQGVKYMFGVVGIPVTEIAFAAQELGIRYVGMRNEQAACYAASVVGYLTD 78

Query: 65  KPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFL 124
           +PGV L+  GPGLI+AL+G+ N+  N WPLLVI GS  +S    G FQEL QV     + 
Sbjct: 79  RPGVCLVTSGPGLINALSGMANANMNCWPLLVIGGSCERSQETMGAFQELPQVETCRLYS 138

Query: 125 KFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMIL 183
           KF+ + +    I  I +KA+   + G  G  Y+D+PAD +     L+ N  +   +   +
Sbjct: 139 KFSARPSSIQAIPSIIEKAVRSSMYGRPGACYVDMPADIV----DLKVNVSSIKYVECCM 194

Query: 184 TPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMAK 243
            P +   + S +     ++   K   I+I  G    +    +R+LV    LPFLPTPM K
Sbjct: 195 PPPVSMAEGSAVCMAASVLRNAKQPLIIIGKGAAYARAEEAVRKLVEQCKLPFLPTPMGK 254

Query: 244 GIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETL 303
           G++PD+ P  V +ARS+AL++AD++++ GARLNWILHFG  P++  +  FIQ D   E L
Sbjct: 255 GVIPDNHPNCVGAARSRALQLADVIVLFGARLNWILHFGLPPRFRPDVKFIQVDICAEEL 314

Query: 304 GDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLR 360
           G+N       +++ GDI      L+E+  R  + W+Y   S   + +REK++ N+     
Sbjct: 315 GNN---VRPAVTLLGDINAVTKQLLEQFDR--TPWQYPPESKWWKTLREKMKSNEAVTKE 369

Query: 361 KEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNAT 420
                   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT  T
Sbjct: 370 LASKNSLPMNYFTVFYHVQEQLPKD-CFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGT 428

Query: 421 MGIGLGYALACKAS----HPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGI 476
           MG+GLG+A+A        +P   V+ ++GDSAFGFS +E+ET  R  L +V++V+NN+GI
Sbjct: 429 MGVGLGFAIAAAVVAKDRNPGQRVICVEGDSAFGFSGLEVETICRYNLPIVLLVVNNNGI 488

Query: 477 YHG-----EKDI--EGD----LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQA 525
           Y G      K++   GD     PP +L  N  Y+ V    G   +FV T  EL +C  Q+
Sbjct: 489 YQGFNADTWKEMLKFGDATFVAPPLSLLPNAHYEQVMTAFGGKGYFVQTPEELQKCLSQS 548

Query: 526 VQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           +       + S+IN++IEP   +K   F W  +  +
Sbjct: 549 LA---DTTKPSLINIMIEPQATRKPQEFHWLTRSNI 581
>ref|XP_001160179.1| PREDICTED: 2-hydroxyphytanoyl-CoA lyase isoform 1 [Pan troglodytes]
          Length = 557

 Score =  648 bits (1672), Expect = 0.0,   Method: Composition-based stats.
 Identities = 211/564 (37%), Positives = 313/564 (55%), Gaps = 33/564 (5%)

Query: 17  GIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVLLIVGGPG 76
            ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY++ +PGV L+V GPG
Sbjct: 7   DVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYLTSRPGVCLVVSGPG 66

Query: 77  LIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGKLTP-DNI 135
           LIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV     + KF+ + +  + I
Sbjct: 67  LIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRLYTKFSARPSSIEAI 126

Query: 136 DMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNICGPDPSKI 195
             + +KA+   I G  G  Y+D+PADF+     L+ N  +   +   ++P I   + S +
Sbjct: 127 PFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMERCMSPPISMAETSAV 182

Query: 196 KKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMAKGIVPDSSPLNVS 255
                +I   K   ++I  G         I++LV  + LPFLPTPM KG+VPD+ P  V 
Sbjct: 183 CTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPMGKGVVPDNHPYCVG 242

Query: 256 SARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDNNVSPGADLS 315
           +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   E LG+N       ++
Sbjct: 243 AARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAEELGNN---VKPTVT 299

Query: 316 IWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRLLRKEKTRGAQLNYN 372
           + G+I      L+EEL +  + W+Y   S   + +REK++ N+         +   +NY 
Sbjct: 300 LLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAASKELASKKSLPMNYY 357

Query: 373 QVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGIGLGYALACK 432
            V+  ++  +      +V+EGANTMDI R       PR RLDAGT  TMG+GLG+A+A  
Sbjct: 358 TVFYHIQEQLPRD-CFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAA 416

Query: 433 ASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNSGIYHG--------- 479
               +      ++ ++GDSAFGFS ME+ET  R  L ++++V+NN+GIY G         
Sbjct: 417 VVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNNGIYQGFDTDTWKEM 476

Query: 480 --EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRETSV 537
              +D    +PP  L  N  Y+ V    G   +FV T  EL +  +Q++       + S+
Sbjct: 477 LKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLRQSLA---DTTKPSL 533

Query: 538 INVIIEP-GEQKQIAFAWQNKPRL 560
           INV+IEP   +K   F W  +  +
Sbjct: 534 INVMIEPQATRKAQDFHWLTRSNM 557
>ref|XP_001160421.1| PREDICTED: 2-hydroxyphytanoyl-CoA lyase isoform 6 [Pan troglodytes]
          Length = 632

 Score =  647 bits (1669), Expect = 0.0,   Method: Composition-based stats.
 Identities = 212/572 (37%), Positives = 315/572 (55%), Gaps = 33/572 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY
Sbjct: 13  QVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGY 72

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV    
Sbjct: 73  LTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACR 132

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   + 
Sbjct: 133 LYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYME 188

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
             ++P I   + S +     +I   K   ++I  G         I++LV  + LPFLPTP
Sbjct: 189 RCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTP 248

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   
Sbjct: 249 MGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICA 308

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTR 357
           E LG+N       +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+  
Sbjct: 309 EELGNN---VKPTVTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAA 363

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT
Sbjct: 364 SKELASKKSLPMNYYTVFYHIQEQLPRD-CFVVSEGANTMDIGRTVLQNYLPRHRLDAGT 422

Query: 418 NATMGIGLGYALACKASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A      +      ++ ++GDSAFGFS ME+ET  R  L ++++V+NN
Sbjct: 423 FGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNN 482

Query: 474 SGIYHG-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G            +D    +PP  L  N  Y+ V    G   +FV T  EL +  
Sbjct: 483 NGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSL 542

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFA 553
           +Q++       + S+INV+IEP   +K     
Sbjct: 543 RQSLA---DTTKPSLINVMIEPQATRKAQELP 571
>ref|NP_001086822.1| MGC82654 protein [Xenopus laevis]
 gb|AAH77507.1| MGC82654 protein [Xenopus laevis]
          Length = 577

 Score =  645 bits (1665), Expect = 0.0,   Method: Composition-based stats.
 Identities = 234/579 (40%), Positives = 322/579 (55%), Gaps = 37/579 (6%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L    +  +FGIVGIP++++A    A GIK++  RNEQAA YAASA GY++
Sbjct: 14  TGAQIIAEALVAQNVKYMFGIVGIPVIEIAVAAQAAGIKYVGMRNEQAACYAASAVGYLT 73

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+V GPGLI+AL+G+ NS  N WPL+V+AGSS  +    G FQE  QV     +
Sbjct: 74  GRPGVCLVVSGPGLINALSGMANSNMNCWPLIVLAGSSDTNQETMGAFQEFPQVETCRLY 133

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
            KF+ + +  + I ++ +KA+   I G  G  Y+D+P DF+        N          
Sbjct: 134 SKFSARPSSLEAIPVVIEKAVRSSIYGRPGSCYVDIPGDFVNKMV----NRSDVRYTECC 189

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTP 240
           L P     DP+ + K V L+   +    LI++GKGA  +  E  IR+LV  + LPFLPTP
Sbjct: 190 LPPPTSLADPTTVNKAVSLLKNAQ--QPLIIVGKGAAFSHAEKSIRKLVQDYGLPFLPTP 247

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD+ P  V++ARS AL+ AD++L+LGARLNWILHFG  P++  +   IQ D   
Sbjct: 248 MGKGVVPDNHPNCVAAARSSALQNADVILLLGARLNWILHFGLPPRFRPDVKIIQVDICA 307

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR---EKIQLNQTR 357
           E LG NNV P A L   GDI      L+E L +  + WKY    +  +    KI+ N+  
Sbjct: 308 EELG-NNVKPAASL--LGDIDAVTQQLLEHLGK--TSWKYPANTEWWKTLMTKIRANEEN 362

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                      +NY  V+  ++  + +   I+V+EGANTMDI R       PR RLDAGT
Sbjct: 363 SKVLASQTSLPMNYYTVFQYVKESLPN-NCIIVSEGANTMDIGRTILQNYHPRHRLDAGT 421

Query: 418 NATMGIGLGYALAC----KASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A     K   PE  VV ++GDSAFGFS ME ET  R  L ++I+V+NN
Sbjct: 422 FGTMGVGLGFAIAAAMITKDECPEQRVVCVEGDSAFGFSGMEAETMCRYNLPIIIIVVNN 481

Query: 474 SGIYHG-------EKDIEGDL----PPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY+G       E    GD     PP AL  N  Y+ V    G   +F  T  EL    
Sbjct: 482 NGIYNGFDEGTWNEMIKSGDPATIAPPVALMPNAHYEQVMMAFGGKGYFARTPEELQNAL 541

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           + +      K   S+INV+I+P  ++K+  F W  +  L
Sbjct: 542 RASFA---EKNGPSLINVMIDPVSDRKKQDFHWLTRSNL 577
>ref|XP_001160475.1| PREDICTED: 2-hydroxyphytanoyl-CoA lyase isoform 7 [Pan troglodytes]
          Length = 628

 Score =  645 bits (1664), Expect = 0.0,   Method: Composition-based stats.
 Identities = 212/569 (37%), Positives = 315/569 (55%), Gaps = 33/569 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY
Sbjct: 13  QVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGY 72

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  QV    
Sbjct: 73  LTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACR 132

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +  + I  + +KA+   I G  G  Y+D+PADF+     L+ N  +   + 
Sbjct: 133 LYTKFSARPSSIEAIPFVIEKAVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYME 188

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
             ++P I   + S +     +I   K   ++I  G         I++LV  + LPFLPTP
Sbjct: 189 RCMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTP 248

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   
Sbjct: 249 MGKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICA 308

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTR 357
           E LG+N       +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+  
Sbjct: 309 EELGNN---VKPTVTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAA 363

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                  +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT
Sbjct: 364 SKELASKKSLPMNYYTVFYHIQEQLPRD-CFVVSEGANTMDIGRTVLQNYLPRHRLDAGT 422

Query: 418 NATMGIGLGYALACKASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A      +      ++ ++GDSAFGFS ME+ET  R  L ++++V+NN
Sbjct: 423 FGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNN 482

Query: 474 SGIYHG-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY G            +D    +PP  L  N  Y+ V    G   +FV T  EL +  
Sbjct: 483 NGIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSL 542

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQI 550
           +Q++       + S+INV+IEP   +K  
Sbjct: 543 RQSLA---DTTKPSLINVMIEPQATRKAQ 568
>ref|NP_001092419.1| 2-hydroxyphytanoyl-CoA lyase [Bos taurus]
 gb|AAI42161.1| MGC160090 protein [Bos taurus]
          Length = 581

 Score =  643 bits (1659), Expect = 0.0,   Method: Composition-based stats.
 Identities = 220/581 (37%), Positives = 326/581 (56%), Gaps = 37/581 (6%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FGIVGIP+ ++A      GI++I  RNEQAA YAASA GY
Sbjct: 16  QVSGARVIAQALKTQDVNYMFGIVGIPVTEIALAAQEVGIRYIGMRNEQAACYAASAVGY 75

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGL+H+L G+ N+  N WPL+VI GSS +S    G FQE  QV    
Sbjct: 76  LTGRPGVCLVVSGPGLVHSLGGMANANMNCWPLIVIGGSSERSQETMGAFQEFPQVEACR 135

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
            + KF+ + +  + I  I +KA+   I G  G  Y+D+PADF+     L+ N  +   + 
Sbjct: 136 LYSKFSARPSSIEAIPSIIEKAVRSSIYGRPGACYVDIPADFV----SLQVNVSSVKYVE 191

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLP 238
             + P I   + S ++    +I   K    L++IGKGA     E  IR+LV    LPFLP
Sbjct: 192 CCMPPPISMAETSAVRMAASVIRNAK--QPLVIIGKGAAYAHAEESIRKLVEQCKLPFLP 249

Query: 239 TPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDS 298
           TPM KG++ D+ P  V++ARS+AL+ AD++++LGARLNWILHFG  P++  +  FIQ D 
Sbjct: 250 TPMGKGVIRDNHPNCVAAARSRALQFADVIVLLGARLNWILHFGLPPRYQPDVKFIQVDI 309

Query: 299 NPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQ 355
             E LG+N       +++ GD+      L+E+  +  + W+Y   S   + +REK++ N+
Sbjct: 310 CAEELGNN---VRPAVTLLGDVNAVTKQLLEQFDK--TPWQYPPESEWWKVLREKMKSNE 364

Query: 356 TRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDA 415
                    +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDA
Sbjct: 365 ALSKELASKKSLPMNYYTVFYHVQEQLPRE-CFVVSEGANTMDIGRTVLQNYLPRHRLDA 423

Query: 416 GTNATMGIGLGYALACKAS----HPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVM 471
           GT  TMG+GLG+A+A        +P   V+ ++GDSAFGFS ME+ET  R  L +V++V+
Sbjct: 424 GTFGTMGVGLGFAIAAAIVAKDRNPGQRVICVEGDSAFGFSGMEVETICRYNLPIVLLVV 483

Query: 472 NNSGIYHG-----EKDI--EGD----LPPTALSKNCRYDLVGKGLGANDFFVNTISELSR 520
           NN+GIY G      K++   GD     PP  L  +  Y+ V    G   +FV T  EL +
Sbjct: 484 NNNGIYQGFDTDSWKEMLKFGDATTVAPPMCLLPHSHYEHVMTAFGGKGYFVQTPEELQK 543

Query: 521 CFQQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
             +Q++         S+IN++IEP G +K   F W  +  L
Sbjct: 544 SLRQSLA---DTTNPSLINIMIEPQGTRKAQDFHWLTRSNL 581
>ref|ZP_02177150.1| acetolactate synthase large subunit [Hydrogenivirga sp. 128-5-R1-1]
 gb|EDP76188.1| acetolactate synthase large subunit [Hydrogenivirga sp. 128-5-R1-1]
          Length = 583

 Score =  639 bits (1649), Expect = 0.0,   Method: Composition-based stats.
 Identities = 121/560 (21%), Positives = 246/560 (43%), Gaps = 21/560 (3%)

Query: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANG-IKFIPCRNEQAASYAASAY 59
           M+        + L++ G++ +FG+ G  I+++ D +  +G IK I  R+EQ A + A  Y
Sbjct: 1   MSRKGADIVIETLKEEGVEVIFGLPGGAIMEVYDALYRDGSIKHILARHEQGAGHMAEGY 60

Query: 60  GYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSL 119
              + K GV +   GPG  + +  I ++  +  P++VI G      I    FQE+D V +
Sbjct: 61  AKATGKVGVAMTTSGPGATNIVTPIADAYMDSVPMVVITGQVPTHMIGNDAFQEVDIVGI 120

Query: 120 LSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNE 178
             P  K    +   D + ++ +KA      G  G   +D+P D  +    ++       +
Sbjct: 121 TRPITKHNFLVRDIDELPLVIRKAFYIASTGRPGPVLVDIPKDITQQLSDVKIPSMDEVK 180

Query: 179 LPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLP 238
             +         +  +IKK  +LI++ K   + +  G    +   E+  L     +P   
Sbjct: 181 RSLPGYKPHVEGNIQQIKKAAKLIMEAKRPVLYVGGGAVNSEAQEELIELAELMKIPVTT 240

Query: 239 TPMAKGIVPDSSPL-------NVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSES 291
           T   KG  P+  PL       + +   + A+  +D+++ +GAR +  +  G   ++  ++
Sbjct: 241 TTQGKGAFPEDHPLALRMLGMHGTYYANMAVYNSDLLIAVGARFDDRVT-GKIDEFAPDA 299

Query: 292 IFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKI 351
             I  D +P ++  N      D+ I GD+ + +  L+ EL R+ +   Y   ++   E+I
Sbjct: 300 KIIHIDIDPASISKN---IIVDVPIVGDVKIVLRKLINELKRKGAKIAYPEERERWIEQI 356

Query: 352 QLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRR 411
           +  +       +     +    V   +  + +    I+   G + M  A + F    PR+
Sbjct: 357 EKWKKLHPLTYRNSKKVIKPQYVIEQIHKVTNGDAIIVPGVGQHQMW-AAMFFKYSYPRQ 415

Query: 412 RLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVM 471
            L++G   TMG GL   +  K   PE +V ++ GD +F  +  EI TAV+ ++ + + ++
Sbjct: 416 FLNSGGLGTMGFGLPAGIGAKVGRPEKEVFVVDGDGSFVMTMQEIITAVQYRIPVKVAII 475

Query: 472 NNS--GIYHGEKDIEGD--LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           NN+  G+    +++  D       LS    +  + + +GA  F      E+    ++A++
Sbjct: 476 NNAYLGMVRQWQELFYDKRYSEVDLSLQPDFVKLAESMGAVGFRAEKPKEVREILEEAMK 535

Query: 528 LSRTKRETSVINVIIEPGEQ 547
           +     +  +++ +++  E 
Sbjct: 536 ID---DKPVIMDFVVDREEN 552
>ref|NP_001017332.1| hypothetical protein LOC550086 [Xenopus tropicalis]
 emb|CAJ81348.1| 2-hydroxyphytanoyl-CoA lyase (hpcl) [Xenopus tropicalis]
          Length = 577

 Score =  637 bits (1644), Expect = 0.0,   Method: Composition-based stats.
 Identities = 234/579 (40%), Positives = 324/579 (55%), Gaps = 37/579 (6%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYIS 63
           T  Q  A+ L    +  +FGIVGIP++++A    A GIK++  RNEQAA YAASA GY++
Sbjct: 14  TGAQIIAEALVAQNVKYMFGIVGIPVIEIAVAAQAAGIKYVGMRNEQAACYAASAVGYLT 73

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            +PGV L+V GPGLI+AL+G+ NS  N WPL+V+AGSS  +    G FQE  QV     +
Sbjct: 74  GRPGVCLVVSGPGLINALSGMANSNMNCWPLIVLAGSSDTNQETMGAFQEFPQVETSRLY 133

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
            KF+ + +  + I ++ +KA+   I G  G  Y+D+P DF+        N          
Sbjct: 134 SKFSARPSSLEAIPVVIEKAVRSSIYGRPGSCYVDIPGDFVNKMV----NRSDVRYTECC 189

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPFLPTP 240
           L P     DP+ + K V  +   +    L+++GKGA  +  E  I +LV    LPFLPTP
Sbjct: 190 LPPPTSLADPTAVHKAVLELKNAQ--QPLVIVGKGAAFSRAERSISKLVQDCGLPFLPTP 247

Query: 241 MAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNP 300
           M KG+VPD+ P  V++ARS AL+ AD++L+LGARLNWILHFG  P++  +   IQ D   
Sbjct: 248 MGKGVVPDNHPNCVAAARSSALQNADVILLLGARLNWILHFGLPPRFRPDVKIIQIDICA 307

Query: 301 ETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTR 357
           E LG NNV P A L   GDI      L+E ++  ++ WKY   +   + +R KI+ N+  
Sbjct: 308 EELG-NNVKPAASL--LGDIDAVTQQLLENIS--ETSWKYPASAEWWKILRAKIRSNEEN 362

Query: 358 LLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGT 417
                      +NY  V+  ++  +     I+V+EGANTMDI R   P   PR RLDAGT
Sbjct: 363 SKVLASQTSLPMNYYTVFKYVKDALPS-NCIIVSEGANTMDIGRTVLPNYHPRHRLDAGT 421

Query: 418 NATMGIGLGYALAC----KASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
             TMG+GLG+A+A     K   PE  VV I+GDSAFGFS ME ET  R +L ++I+V+NN
Sbjct: 422 FGTMGVGLGFAIAAAMITKDECPEQRVVCIEGDSAFGFSGMEAETMCRYKLPIIIIVVNN 481

Query: 474 SGIYHG-------EKDIEGDL----PPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
           +GIY+G       E    GD     PP AL  N  Y+ V K  G   +F  T  EL    
Sbjct: 482 NGIYNGFDEGTWNEMMESGDPATMAPPVALMPNAHYEQVMKAFGGKGYFARTPEELQNAL 541

Query: 523 QQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           + +      K   S+INV+I+P  ++K+  F W  +  L
Sbjct: 542 KSSFA---EKAVPSLINVMIDPVSDRKKQEFHWLTRSNL 577
>ref|ZP_00822285.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Yersinia bercovieri ATCC 43970]
          Length = 591

 Score =  635 bits (1638), Expect = e-180,   Method: Composition-based stats.
 Identities = 124/563 (22%), Positives = 235/563 (41%), Gaps = 26/563 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 17  MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 76

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 77  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGYDAFQECDMVG 136

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   ID+P D +     +        
Sbjct: 137 ISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKMPYAYPEQV 196

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNS--HEIRRLVNTFNLP 235
            L     P + G    +IK+ +Q IL  K    ++ +G GA+ ++   E+       NLP
Sbjct: 197 SL-RSYNPTVQG-HRGQIKRALQTILAAKRP--IMYVGGGAINSACHEELLAFAEKLNLP 252

Query: 236 FLPTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
              + M  G  P +         ++ +   + A+   D++  +G R +         K+ 
Sbjct: 253 VTSSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAIGVRFDDR-TTNNLAKYC 311

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
            ++  +  D +P ++     +  AD+ I GD    +  ++E L + DS   +  ++    
Sbjct: 312 PDASVVHIDIDPTSISK---TVNADIPIVGDAKQVLVQMLELLPQIDSAQDFDSLRDWW- 367

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           + I+  + R          ++    V  TL  L      +    G + M  A + +P D 
Sbjct: 368 QSIEQWRARNCLGYNKESGKIKPQAVIETLHRLTKGDAYVTSDVGQHQM-FAALYYPFDK 426

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PR  +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  L +++
Sbjct: 427 PRHWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYNLPVLV 486

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +D+   G    + +     +  + +  G     + T  EL      
Sbjct: 487 LNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGIAIRTPDELESKLAD 546

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+           ++V ++  E 
Sbjct: 547 ALSQLSETNRLVFVDVTVDETEH 569
>ref|ZP_00825910.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Yersinia mollaretii ATCC 43969]
          Length = 585

 Score =  634 bits (1635), Expect = e-180,   Method: Composition-based stats.
 Identities = 122/563 (21%), Positives = 234/563 (41%), Gaps = 26/563 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 11  MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 70

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 71  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGYDAFQECDMVG 130

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   ID+P D +     +        
Sbjct: 131 ISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKMPYAYPEQV 190

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNS--HEIRRLVNTFNLP 235
            L     P + G    +IK+ +Q IL  K    ++ +G GA+ ++   E+       NLP
Sbjct: 191 SL-RSYNPTVQG-HRGQIKRALQTILAAKRP--IMYVGGGAINSACHEELLAFAEKLNLP 246

Query: 236 FLPTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
              + M  G  P +         ++ +   + A+   D++  +G R +         K+ 
Sbjct: 247 VTSSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYC 305

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
            ++  +  D +P ++     +  AD+ I GD    +  +++ L + D    +  ++    
Sbjct: 306 PDATVVHIDIDPTSISK---TVNADIPIVGDAKQVLVQMLDLLPQIDCAQDFDSLRDWW- 361

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           + I+  + R          ++    V  TL  L      +    G + M  A + +P D 
Sbjct: 362 QSIEQWRARNCLGYNKESGKIKPQAVIETLHRLTKGDAYVTSDVGQHQM-FAALYYPFDK 420

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PR  +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  L +++
Sbjct: 421 PRHWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYNLPVLV 480

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +D+   G    + +     +  + +  G     + T  EL      
Sbjct: 481 LNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGIAIRTPEELESKLAD 540

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+           ++V ++  E 
Sbjct: 541 ALSQLSETNRLVFVDVTVDETEH 563
>ref|NP_613816.1| acetolactate synthase catalytic subunit [Methanopyrus kandleri
           AV19]
 gb|AAM01746.1| Acetolactate synthase, large subunit [Methanopyrus kandleri AV19]
          Length = 565

 Score =  632 bits (1632), Expect = e-179,   Method: Composition-based stats.
 Identities = 147/557 (26%), Positives = 245/557 (43%), Gaps = 29/557 (5%)

Query: 4   TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVAN-GIKFIPCRNEQAASYAASAYGYI 62
           T  +   + L++ G++ +FG  G  ++ + D +     I+ I  R+EQ A++AA  Y  +
Sbjct: 6   TGARVLVECLKEEGVEHIFGYPGGAVLPIYDEIYDEVSIEHILVRHEQGAAHAADGYARV 65

Query: 63  SDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSP 122
             KPGV +   GPG  + + GI  +  +  P++ I G    + I K  FQE+D V +  P
Sbjct: 66  KGKPGVCMATSGPGATNLVTGIATAYMDSSPVIAITGQVPTTMIGKDAFQEVDAVGVFMP 125

Query: 123 FLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPM 181
             K   ++  P+ I  + ++A    I G  G  +IDVP D  E E  +E       E   
Sbjct: 126 ITKHNYQIGKPEEIPEVVKEAFKIAITGRPGPVHIDVPKDVQEAEVDVEIPKTVEVEGLN 185

Query: 182 ILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPM 241
           ++        P +IK+  +L+ + +   IL   G      + E+  L      P   T M
Sbjct: 186 VVK----RGHPVQIKRAAELLAEAERPVILAGGGCVISNATRELIELAELLGAPVATTLM 241

Query: 242 AKGIVPDSSPL-------NVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFI 294
            KG  P+  PL       + + A + AL   D++L +G R +     G    +  E+  I
Sbjct: 242 GKGAFPEDHPLALGMAGMHGTKAANYALTECDVLLAVGCRFSDR-TTGDPSGFAPEAKII 300

Query: 295 QFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLN 354
             D +P  +G N      D+ I GD  L +  L++EL R+    +     + I E     
Sbjct: 301 HIDIDPAEIGKN---IPVDVPIVGDAKLVLRDLIKELKRRKYLRERKRWGERIEELKA-- 355

Query: 355 QTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTI-LVTEGANTMDIARISFPTDAPRRRL 413
           +  +  +      +++  ++   L   + D   I     G N M +AR  FP + PRR +
Sbjct: 356 EVEMPPESTESDQRISPRELVRVLHEALKDRDYILTTDVGQNQMWMAR-YFPVEEPRRFI 414

Query: 414 DAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
            +G   TMG GL  AL  K + PE  VV + GD  F  +A E+ TAV   + + + VM+N
Sbjct: 415 SSGGLGTMGFGLPAALGAKVAAPEKTVVAVVGDGGFLMTAQELATAVDNDIEVKVFVMDN 474

Query: 474 S--GIYHGEKDIEGD--LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLS 529
              G+    + +  D  L  + L +      + +  GA    V   SEL    ++A +  
Sbjct: 475 RLLGMVAQWQRLFYDERLSESKLDEKTDIVKLTESYGAAGITVEEPSELESAVEEAFE-- 532

Query: 530 RTKRETSVINVIIEPGE 546
                T V++V ++P E
Sbjct: 533 --TPGTVVVDVFVDPEE 547
>ref|ZP_00831646.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Yersinia frederiksenii ATCC 33641]
          Length = 600

 Score =  631 bits (1629), Expect = e-179,   Method: Composition-based stats.
 Identities = 125/563 (22%), Positives = 239/563 (42%), Gaps = 26/563 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 26  MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 85

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 86  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGYDAFQECDMVG 145

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   ID+P D +     +        
Sbjct: 146 ISRPVVKHSFLVKRTEDIPSVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKMPYAYPDQV 205

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNS--HEIRRLVNTFNLP 235
            L     P + G    +IK+ +Q IL  K    ++ +G GA+ ++   E+  L    NLP
Sbjct: 206 SL-RSYNPTVQG-HRGQIKRALQTILAAKKP--IMYVGGGAINSACHAELLTLAEQLNLP 261

Query: 236 FLPTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
              + M  G  P +         ++ +   + A+   D++  +G R +         K+ 
Sbjct: 262 VTSSLMGLGAFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYC 320

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
            ++  +  D +P ++     +  AD+ I GD    +T +++ L++ D    +  ++    
Sbjct: 321 PDATVLHIDIDPTSISK---TVTADIPIVGDAKQVLTQMLDLLSQIDCVQDFDSLRDWW- 376

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           + I+  + R          ++    V  TL  L      +    G + M  A + +P D 
Sbjct: 377 QSIEQWRARDCLSYSKDSGKIKPQAVIETLHRLTKGDAYVTSDVGQHQM-FAALYYPFDK 435

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  L +++
Sbjct: 436 PRRWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYNLPVLV 495

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +D+   G    + +     +  + +  G     + T  EL     +
Sbjct: 496 LNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVSIRTPDELESKLAE 555

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+           ++V ++  E 
Sbjct: 556 ALTQLSETNRLVFVDVTVDETEH 578
>ref|ZP_02478424.1| acetolactate synthase 3 catalytic subunit [Haemophilus parasuis
           29755]
 gb|EDS24442.1| acetolactate synthase 3 catalytic subunit [Haemophilus parasuis
           29755]
          Length = 573

 Score =  630 bits (1627), Expect = e-179,   Method: Composition-based stats.
 Identities = 135/559 (24%), Positives = 242/559 (43%), Gaps = 25/559 (4%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANG-IKFIPCRNEQAASYAASAYG 60
             +  +   Q L+  G++ VFG  G  ++ + D +   G IK +  R+EQAA + A  Y 
Sbjct: 3   KLSGAEMIVQSLRDEGVEYVFGYPGGSVLDIYDAIHTLGGIKHVLVRHEQAAVHMADGYA 62

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
             + K G +L+  GPG  +A+ GI  + ++  PL+V +G    S I    FQE D V + 
Sbjct: 63  RSTGKVGCVLVTSGPGATNAITGIATAYTDSIPLVVFSGQVPSSLIGTDAFQECDMVGIS 122

Query: 121 SPFLKFTGKLT-PDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNEL 179
            P +K +  +T P+ I  I +KA      G  G   IDVP D +      + +    + +
Sbjct: 123 RPVVKHSFLVTNPEEIPEIIKKAFYIASTGRPGPVVIDVPKDMVN--PANKFSYHYPDSV 180

Query: 180 PMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPT 239
            +            +IKK ++ IL  K   + +  G    +++ E+       NLP   +
Sbjct: 181 SLRSYNPTVQGHKGQIKKALKAILVAKKPVLFVGGGAVISESNKELIEFAQKLNLPVTSS 240

Query: 240 PMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESI 292
            M  G  P +         ++ +   + A+  +D++L +G R +         K+   + 
Sbjct: 241 LMGLGAYPSTDKQFLGMLGMHGTYEANNAMHESDLILGIGVRFDDR-TTNNLAKYCPNAK 299

Query: 293 FIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQ 352
            I  D +P ++     +  A + I GD    +   +  L  ++     S +    ++  +
Sbjct: 300 VIHIDIDPTSISK---TVPAYIPIVGDAKFVLEEFLALLGEENLAKGQSDLTAWWQQINE 356

Query: 353 LNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRR 412
               + LR E++    +   QV  T+  L +    I    G + M  A + +P D PRR 
Sbjct: 357 WKARQCLRFEQSDV--IKPQQVIQTIYKLTNGDAYIASDVGQHQM-FAALHYPFDKPRRW 413

Query: 413 LDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMN 472
           +++G   TMG GL  A+  K +HPE  VV + GD +   +  E+ TA +    +VIV +N
Sbjct: 414 INSGGLGTMGFGLPAAMGVKFAHPEATVVCVTGDGSIQMNIQELSTAKQYDTPVVIVSLN 473

Query: 473 NS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQL 528
           N   G+    +DI   G    + ++    +  + +  G     +NT  EL     QA  +
Sbjct: 474 NRFLGMVKQWQDIIYAGRHSQSYMNSLPDFVKLAEAYGHVGIQINTPDELEEKLAQAFAI 533

Query: 529 SRTKRETSVINVIIEPGEQ 547
              K +   ++V+++  E 
Sbjct: 534 ---KDKLVFVDVLVDETEH 549
>ref|ZP_00833010.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Yersinia intermedia ATCC 29909]
          Length = 585

 Score =  630 bits (1626), Expect = e-179,   Method: Composition-based stats.
 Identities = 125/563 (22%), Positives = 236/563 (41%), Gaps = 26/563 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 11  MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 70

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 71  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGYDAFQECDMVG 130

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   ID+P D +     +        
Sbjct: 131 ISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKMPYAYPDQV 190

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNS--HEIRRLVNTFNLP 235
            L     P + G    +IK+ +Q IL  K    ++ +G GA+ ++   E+  L    NLP
Sbjct: 191 SL-RSYNPTVQG-HRGQIKRALQTILAAKKP--IMYVGGGAINSACHEELLVLAEKLNLP 246

Query: 236 FLPTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
              + M  G  P +         ++ +   + A+   D++  +G R +         K+ 
Sbjct: 247 VTSSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYC 305

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
             +  +  D +P ++     +  AD+ I GD    +  ++E L++ D       ++    
Sbjct: 306 PNATVVHIDIDPTSISK---TVNADIPIVGDAKQVLVQMLELLSQIDCTQDCDSLRDWW- 361

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           + I+  + R          ++    V  TL  L      +    G + M  A + +P D 
Sbjct: 362 QSIEQWRARNCLSYNKDSGKIKPQAVIETLHRLTSGDAYVTSDVGQHQM-FAALYYPFDK 420

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  L +++
Sbjct: 421 PRRWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYNLPVLV 480

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +D+   G    + +     +  + +  G     + T  EL      
Sbjct: 481 LNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVSIRTPDELESKLAD 540

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+      +    ++V ++  E 
Sbjct: 541 ALTQLSETKRLVFVDVTVDETEH 563
>ref|NP_213319.1| acetolactate synthase large subunit [Aquifex aeolicus VF5]
 gb|AAC06706.1| acetolactate synthase large subunit [Aquifex aeolicus VF5]
          Length = 585

 Score =  630 bits (1626), Expect = e-179,   Method: Composition-based stats.
 Identities = 116/558 (20%), Positives = 240/558 (43%), Gaps = 21/558 (3%)

Query: 3   TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANG-IKFIPCRNEQAASYAASAYGY 61
                   + L+  G++ VFG+ G  I+++ D +   G IK I  R+EQ A + A  Y  
Sbjct: 4   KKGADIVIETLKAEGVEVVFGLPGGAIMEVYDALYRLGGIKHILARHEQGAGHMAEGYAK 63

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
            + K GV+++  GPG  + +  I ++  +  PL+ I G      I    FQE+D V +  
Sbjct: 64  ATGKVGVVMVTSGPGATNLVTPIADAYMDSVPLVAITGQVPTHLIGNDAFQEVDIVGITR 123

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
           P  K    +   + + +I ++A      G  G   +D+P D  +    ++       +  
Sbjct: 124 PITKHNFLVKSIEELPLILREAFYIARTGRPGPVLVDLPKDVTQQIADVKIPSDEEVKAA 183

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
           +         +P +IKK  +LI+  K   + +  G    +   E+  L     +P   T 
Sbjct: 184 LPGYKPHVEGNPQQIKKAAELIMSAKRPVLYVGGGAVNSEAQEELIELAELMQIPVTTTT 243

Query: 241 MAKGIVPDSSPLNV-------SSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIF 293
             KG  P++ PL++       +   + A+  +D+++ +GAR +  +  G   ++   +  
Sbjct: 244 QGKGAFPETHPLSLRMLGMHGTYYANMAVYNSDLLIAVGARFDDRVT-GKIDEFAPGAKI 302

Query: 294 IQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQL 353
           I  D +P ++  N      D+ I GD+ + +  L+ E+ ++ +   Y   +++  E+I+ 
Sbjct: 303 IHIDIDPASISKN---ITVDVPIVGDVKIVLRKLINEIKKRGAKILYPEERKKWLEQIEK 359

Query: 354 NQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRL 413
            +       +     +    V   L    +    I+   G + M  A + +    PR+ +
Sbjct: 360 WKKLHPLTYRNSDKVIKPQYVIEQLWEATNGEAIIVPGVGQHQMW-AAMFYKFKYPRQFI 418

Query: 414 DAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
           ++G   TMG GL   +  K   P+ +V ++ GD +F  +  E+ TAV+ ++ + + ++NN
Sbjct: 419 NSGGLGTMGFGLPAGIGAKIGRPDREVWVVDGDGSFVMTMQEVITAVQYKVPVKVAIINN 478

Query: 474 S--GIYHGEKDIEGD--LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLS 529
           +  G+    +++  D       LS    +  + + +GA         E+    ++A ++ 
Sbjct: 479 AYLGMVRQWQELFYDKRYSEVDLSVQPDFVKLAEAMGAVGMRAKKPKEVREVIEEARKID 538

Query: 530 RTKRETSVINVIIEPGEQ 547
                  +I+  ++  E 
Sbjct: 539 ---DRPVIIDFWVDREEN 553
>ref|XP_975143.1| PREDICTED: similar to CG11208-PA [Tribolium castaneum]
          Length = 568

 Score =  629 bits (1624), Expect = e-178,   Method: Composition-based stats.
 Identities = 225/581 (38%), Positives = 327/581 (56%), Gaps = 37/581 (6%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
                   AQ L++ GI+ VFGI G P+++L+  +   GI +I  RNEQAA YAA A GY
Sbjct: 3   EIDGNAILAQALKEQGIEYVFGICGFPVIELSMALQTAGIHYIGMRNEQAACYAAQAIGY 62

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++  PG +L+V GPGL+H  AG+ N+  N WP++VI GS  Q     GGFQE  QV L  
Sbjct: 63  LTGVPGGVLVVSGPGLLHVCAGMANAQVNCWPVVVIGGSCPQDHEGIGGFQECYQVELAR 122

Query: 122 PFLKFTGK-LTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDR--TGNE 178
           P+ K++ +  +   I    +KA+     G  G  Y+D P + ++    ++   +  T  E
Sbjct: 123 PYCKYSARPPSLALIPQHVEKAVRLATYGRPGAVYLDFPGNLLQARTTIDKIPKQYTAPE 182

Query: 179 LPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHE--IRRLVNTFNLPF 236
           +P+I       P+P KI +   LI+  +    L+++GKGA     E  +R LV++ NLPF
Sbjct: 183 IPVIY------PEPRKIDEAAALIMGAQRP--LVIVGKGAAYARAEGQVRELVDSTNLPF 234

Query: 237 LPTPMAKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQF 296
           L TPM KG+V D++P ++  ARS AL+ AD+VL+LGARLNWILHFG  P++N     IQ 
Sbjct: 235 LATPMGKGVVSDTNPNSIQPARSLALQRADVVLLLGARLNWILHFGRPPRYNPNVKVIQI 294

Query: 297 DSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCW-KYSGVKQEIREKIQLNQ 355
           D   E L   N S  A ++I  D+  +V  LV+ L R++  + K S    ++ +KIQ N+
Sbjct: 295 DVCAEEL---NNSVKAAVAIQSDLKPAVGQLVQSLKRRNFTFSKNSDWWNDLNKKIQDNK 351

Query: 356 TRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDA 415
            ++          LNY  V+  L+ ++     I V+EGANTMDI R       PR RLDA
Sbjct: 352 RKVQEMTLDVSEPLNYYAVFHHLQEVLPQNPII-VSEGANTMDIGRAVLMNGLPRHRLDA 410

Query: 416 GTNATMGIGLGYALACKASH----PELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVM 471
           GT  TMG+GLG+A+A         P+  V+ ++GDSAFGFS MEIET VR +L ++IVV+
Sbjct: 411 GTFGTMGVGLGFAIAAALYCRHFEPKKRVICVEGDSAFGFSGMEIETMVRYKLPVIIVVV 470

Query: 472 NNSGIYHGE-KDIEGDL----------PPTALSKNCRYDLVGKGLGANDFFVNTISELSR 520
           NNSGIY G  +++  DL          PPT L  +  Y+ +    G   +   TI+EL +
Sbjct: 471 NNSGIYGGLPQEVYKDLQESGEVTKVTPPTTLFTSTHYEKMMTMFGRQGYHCTTIAELQK 530

Query: 521 CFQQAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
             ++A+   +     S+INVII P  ++K   F W  + +L
Sbjct: 531 AVKEAL---KETEGPSIINVIISPSADRKPQDFNWLTESKL 568
>ref|ZP_01991840.1| acetolactate synthase, large subunit, biosynthetic type [Vibrio
           parahaemolyticus AQ3810]
 gb|EDM58291.1| acetolactate synthase, large subunit, biosynthetic type [Vibrio
           parahaemolyticus AQ3810]
          Length = 574

 Score =  628 bits (1621), Expect = e-178,   Method: Composition-based stats.
 Identities = 130/563 (23%), Positives = 247/563 (43%), Gaps = 27/563 (4%)

Query: 1   MT--TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA--NGIKFIPCRNEQAASYAA 56
           MT   +  +   Q L +  ++ +FG  G  ++ + D + A  + IK +  R+EQAA++ A
Sbjct: 1   MTAMLSGAEMVVQSLIEENVEQIFGYPGGSVLDIYDALHAKTDQIKHVLVRHEQAATHMA 60

Query: 57  SAYGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQ 116
             Y   + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   S I    FQE D 
Sbjct: 61  DGYARATGKPGVVLVCSGPGATNTITGIATAYMDSIPMIVISGNVPNSLIGNDAFQECDI 120

Query: 117 VSLLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRT 175
           V +  P +K +  +   ++I    +KA      G  G   ID+P D +  +  L    + 
Sbjct: 121 VGVSRPVVKHSFLVKKAEDIPETIKKAFYISTTGRPGPVVIDLPKDVMNPQIKLP--YQY 178

Query: 176 GNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLP 235
              + M            +IKK ++ +++ K   + +  G         I  L +  NLP
Sbjct: 179 PESISMRSYKPTTSGHKGQIKKALKSLIEAKKPVLYVGGGAVISGAHEHILELADKLNLP 238

Query: 236 FLPTPMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
            + T M  G  P +         ++ +   + A+  AD++  +G R +         K+ 
Sbjct: 239 VVSTLMGLGAFPGTHKNSLGMLGMHGTYEANMAMHEADLIFGIGVRFDDR-TTNNLEKYC 297

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
             +  +  D +P ++  N      DL I G     +T ++  L  QD     + + +   
Sbjct: 298 PNAKVMHIDIDPSSISKN---VKVDLPIVGSAEKVLTTMLGLLAEQDCSNDEAAITKWW- 353

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           + IQ+ + R     +T   ++   QV  TL  L +    +    G + M  A + +P + 
Sbjct: 354 DDIQVWRDRQCLSYETSSDRIKPQQVIETLHKLTNGDAYVASDVGQHQM-FAALYYPFNK 412

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL   +  K + PE +VV++ GD +   +  E+ TA++  + + I
Sbjct: 413 PRRWINSGGLGTMGFGLPAGMGVKFAMPEEEVVVVTGDGSIQMNIQELSTAMQYDIPVKI 472

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +DI  +G    + +S    +  + +  G     + T  +L    Q+
Sbjct: 473 INLNNRFLGMVKQWQDIIYQGRHSNSYMSSVPDFAAIAEAYGHVGIRIETPDQLEEGLQK 532

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+ +   K     +++ ++  E 
Sbjct: 533 ALDM---KDRLVFVDINVDETEH 552
>ref|YP_001005008.1| acetolactate synthase 3 catalytic subunit [Yersinia enterocolitica
           subsp. enterocolitica 8081]
 emb|CAL10768.1| acetolactate synthase isozyme III large subunit [Yersinia
           enterocolitica subsp. enterocolitica 8081]
          Length = 575

 Score =  628 bits (1620), Expect = e-178,   Method: Composition-based stats.
 Identities = 124/563 (22%), Positives = 235/563 (41%), Gaps = 26/563 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGFDAFQECDMVG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   ID+P D +     +        
Sbjct: 121 ISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKMPYAYPEQV 180

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNS--HEIRRLVNTFNLP 235
            L     P + G    +IK+ +Q IL  K    ++ +G GA+ ++   E+  L    NLP
Sbjct: 181 SL-RSYNPTVQG-HRGQIKRALQTILAAKRP--IMYVGGGAINSACHEELLTLAEKLNLP 236

Query: 236 FLPTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
              + M  G  P +         ++ +   + A+   D++  +G R +         K+ 
Sbjct: 237 VTSSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYC 295

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
             +  +  D +P ++     +  AD+ I GD    +T +++ L + D    +  ++    
Sbjct: 296 PNAAVVHIDIDPTSISK---TVEADIPIVGDAKQVLTQMLDLLPQIDCAQDFDSLRDWW- 351

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           + I+  + R          ++    V  TL  L      +    G + M  A + +P D 
Sbjct: 352 QSIEQWRARDCLSYAKDSGKIKPQAVIETLHRLTKGDAYVTSDVGQHQM-FAALYYPFDK 410

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PR  +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  L +++
Sbjct: 411 PRHWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYNLPVLV 470

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +D+   G    + +     +  + +  G     + T  EL      
Sbjct: 471 LNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVSIRTPDELESKLAD 530

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+           ++V ++  E 
Sbjct: 531 ALTQLSETNRLVFVDVTVDETEH 553
>ref|NP_796731.1| acetolactate synthase 3 catalytic subunit [Vibrio parahaemolyticus
           RIMD 2210633]
 dbj|BAC58615.1| acetolactate synthase III, large subunit [Vibrio parahaemolyticus
           RIMD 2210633]
          Length = 574

 Score =  627 bits (1618), Expect = e-178,   Method: Composition-based stats.
 Identities = 130/563 (23%), Positives = 247/563 (43%), Gaps = 27/563 (4%)

Query: 1   MT--TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA--NGIKFIPCRNEQAASYAA 56
           MT   +  +   Q L +  ++ +FG  G  ++ + D + A  + IK +  R+EQAA++ A
Sbjct: 1   MTAMLSGAEMVVQSLIEENVEQIFGYPGGSVLDIYDALHAKTDQIKHVLVRHEQAATHMA 60

Query: 57  SAYGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQ 116
             Y   + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   S I    FQE D 
Sbjct: 61  DGYARATGKPGVVLVCSGPGATNTITGIATAYMDSIPMIVISGNVPNSLIGNDAFQECDI 120

Query: 117 VSLLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRT 175
           V +  P +K +  +   ++I    +KA      G  G   ID+P D +  +  L    + 
Sbjct: 121 VGVSRPVVKHSFLVKKAEDIPETIKKAFYISTTGRPGPVVIDLPKDVMNPQIKLP--YQY 178

Query: 176 GNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLP 235
              + M            +IKK ++ +++ K   + +  G         I  L +  NLP
Sbjct: 179 PESISMRSYKPTTSGHKGQIKKALKSLIEAKKPVLYVGGGAVISGAHEHILELADKLNLP 238

Query: 236 FLPTPMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
            + T M  G  P +         ++ +   + A+  AD++  +G R +         K+ 
Sbjct: 239 VVSTLMGLGAFPGTHKNSLGMLGMHGTYEANMAMHEADLIFGIGVRFDDR-TTNNLEKYC 297

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
             +  +  D +P ++  N      DL I G     +T ++  L  QD     + + +   
Sbjct: 298 PNAKVMHIDIDPSSISKN---VKVDLPIVGSAEKVLTTMLGLLAEQDCGNDEAAITKWW- 353

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           + IQ+ + R     +T   ++   QV  TL  L +    +    G + M  A + +P + 
Sbjct: 354 DDIQVWRDRQCLSYETSSDRIKPQQVIETLHKLTNGDAYVASDVGQHQM-FAALYYPFNK 412

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL   +  K + PE +VV++ GD +   +  E+ TA++  + + I
Sbjct: 413 PRRWINSGGLGTMGFGLPAGMGVKFAMPEEEVVVVTGDGSIQMNIQELSTAMQYDIPVKI 472

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +DI  +G    + +S    +  + +  G     + T  +L    Q+
Sbjct: 473 INLNNRFLGMVKQWQDIIYQGRHSNSYMSSVPDFAAIAEAYGHVGIRIETPDQLEEGLQK 532

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+ +   K     +++ ++  E 
Sbjct: 533 ALDM---KDRLVFVDINVDETEH 552
>ref|ZP_02961406.1| hypothetical protein PROSTU_03434 [Providencia stuartii ATCC 25827]
 gb|EDU60228.1| hypothetical protein PROSTU_03434 [Providencia stuartii ATCC 25827]
          Length = 575

 Score =  627 bits (1618), Expect = e-178,   Method: Composition-based stats.
 Identities = 127/567 (22%), Positives = 243/567 (42%), Gaps = 34/567 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  I  R+EQAA + A  
Sbjct: 1   MEMLSGAEMVVKSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHILVRHEQAAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  PL+V++G  + S I    FQE D V 
Sbjct: 61  YARSTGEVGVILVTSGPGATNAITGIATAYMDSVPLVVLSGQVASSLIGNDAFQECDMVG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIE------YEKPLEG 171
           +  P +K +  +   ++I    +KA      G  G   ID+P D +       Y  P   
Sbjct: 121 ISRPIVKHSFLIKKAEDIPETIKKAFYIAASGRPGPVVIDLPKDTVNPANKYPYRYPEAV 180

Query: 172 NDRTGNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNT 231
           + R+ N                +IKK +  ++  +     I  G      S EI  L   
Sbjct: 181 SLRSYN--------PTLQGHKGQIKKALTKLIAAQKPVFYIGGGAINANCSAEIIALAEK 232

Query: 232 FNLPFLPTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTS 284
             LP + T M  G  P++         ++ +   ++ +  +D++  +G R +        
Sbjct: 233 LQLPVVSTLMGLGAFPETHHQSVGMLGMHGTYEANKVMHNSDVIFAVGVRFDDR-TTNNL 291

Query: 285 PKWNSESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVK 344
            K+   +  IQ D +P ++     +   D+ I GD  L++  ++ +L +  +      +K
Sbjct: 292 EKYCPNATVIQIDVDPTSISK---TVNTDIPIVGDAKLTLQQMLSQLDQVSTKQNSQALK 348

Query: 345 QEIREKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISF 404
              +E I+  + R   + +T   ++   Q   T+  L +    +    G + M  A + +
Sbjct: 349 TWWKE-IETWRERKCLRYETNSQKVKPQQAIETIYRLTNGEAYVTSDVGQHQM-FAALYY 406

Query: 405 PTDAPRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQL 464
           P D PR  +++G   TMG GL  AL  K +HP+  V+ + GD +   +  E+ TA++  L
Sbjct: 407 PFDKPRHWINSGGLGTMGFGLPAALGVKLAHPQSTVICVTGDGSIQMNIQELSTAMQYGL 466

Query: 465 ALVIVVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSR 520
            +V++ +NN   G+    +D+  +G    + +     +  + +  G     +++  EL  
Sbjct: 467 PVVVLNLNNGFLGMVKQWQDMIYQGRHSQSYMQSLPDFVKLAEAYGHVGISIHSPDELEE 526

Query: 521 CFQQAVQLSRTKRETSVINVIIEPGEQ 547
             +QA+      +    +++ ++  E 
Sbjct: 527 KLKQALVEVNENQRLVFVDINVDETEH 553
>ref|ZP_01261609.1| acetolactate synthase III large subunit [Vibrio alginolyticus
           12G01]
 gb|EAS75064.1| acetolactate synthase III large subunit [Vibrio alginolyticus
           12G01]
          Length = 574

 Score =  627 bits (1618), Expect = e-178,   Method: Composition-based stats.
 Identities = 132/563 (23%), Positives = 245/563 (43%), Gaps = 27/563 (4%)

Query: 1   MT--TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA--NGIKFIPCRNEQAASYAA 56
           MT   +  +   Q L +  ++ +FG  G  ++ + D + A  + IK +  R+EQAA++ A
Sbjct: 1   MTAMLSGAEMVVQSLIEEHVEQIFGYPGGSVLDIYDALHAKTDQIKHVLVRHEQAATHMA 60

Query: 57  SAYGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQ 116
             Y   + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   S I    FQE D 
Sbjct: 61  DGYARATGKPGVVLVCSGPGATNTITGIATAYMDSIPMIVISGNVPNSLIGNDAFQECDI 120

Query: 117 VSLLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRT 175
           V +  P +K +  +   ++I    +KA      G  G   ID+P D +  +  L    + 
Sbjct: 121 VGVSRPVVKHSFLVKKAEDIPETIKKAFYIATTGRPGPVVIDLPKDVMNPQIKLP--YQY 178

Query: 176 GNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLP 235
              L M            +IKK ++ +L+ K   + I  G         I  L +  NLP
Sbjct: 179 PETLSMRSYKPTTSGHKGQIKKALKSLLEAKKPVLYIGGGAVISGAHEHILELSDKLNLP 238

Query: 236 FLPTPMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
            + T M  G  P +         ++ +   + A+  AD++  +G R +         K+ 
Sbjct: 239 VVSTLMGLGAFPGTHKNSLGMLGMHGTYEANMAMHEADLIFGIGVRFDDR-TTNNLEKYC 297

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
             +  +  D +P ++  N      DL I G     +T ++  L  Q S      +     
Sbjct: 298 PNAKVMHIDIDPSSISKN---VKVDLPIVGSAEKVLTTMLGLLAEQGSGNDQDAITAWW- 353

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           + IQ+ + R     +T   ++   QV  TL  L +    +    G + M  A + +P + 
Sbjct: 354 DDIQVWRDRNCLSYETSPERIKPQQVIETLHKLTNGDAYVASDVGQHQM-FAALYYPFNK 412

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL   +  K + P+ +VV++ GD +   +  E+ TA++  + + I
Sbjct: 413 PRRWINSGGLGTMGFGLPAGMGVKFAMPQEEVVVVTGDGSIQMNIQELSTAMQYDIPVKI 472

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +DI  +G    + +S    +  + +  G     + T  +L    Q+
Sbjct: 473 INLNNRFLGMVKQWQDIIYQGRHSNSYMSSVPDFAAIAEAYGHVGIRIETPDQLEEGLQK 532

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+ +   K     +++ ++  E 
Sbjct: 533 ALDM---KDRLVFVDINVDETEH 552
>ref|YP_001444053.1| acetolactate synthase III, large subunit [Vibrio harveyi ATCC
           BAA-1116]
 gb|ABU69826.1| hypothetical protein VIBHAR_00825 [Vibrio harveyi ATCC BAA-1116]
          Length = 574

 Score =  627 bits (1618), Expect = e-178,   Method: Composition-based stats.
 Identities = 133/563 (23%), Positives = 247/563 (43%), Gaps = 27/563 (4%)

Query: 1   MT--TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA--NGIKFIPCRNEQAASYAA 56
           MT   +  +   Q L +  ++ +FG  G  ++ + D + A  + IK +  R+EQAA++ A
Sbjct: 1   MTAMLSGAEMVVQSLIEESVEQIFGYPGGSVLDIYDALHAKTDQIKHVLVRHEQAATHMA 60

Query: 57  SAYGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQ 116
             Y   + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   + I    FQE D 
Sbjct: 61  DGYARATGKPGVVLVCSGPGATNTITGIATAYMDSIPMIVISGNVPNNLIGNDAFQECDI 120

Query: 117 VSLLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRT 175
           V +  P +K +  +   ++I    +KA      G  G   ID+P D +  +  L      
Sbjct: 121 VGVSRPVVKHSFLVKKAEDIPETIKKAFYISTTGRPGPVVIDLPKDILNPQIKLPYEYPE 180

Query: 176 GNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLP 235
              +     P   G    +IKK ++ +++ K   + I  G         I+ L +  NLP
Sbjct: 181 SISM-RSYKPTTSG-HKGQIKKALKSLVEAKKPVLYIGGGAVISGAHEHIQALSDELNLP 238

Query: 236 FLPTPMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
            + T M  G  P +         ++ +   + A+  AD++  +G R +         K+ 
Sbjct: 239 VVSTLMGLGAFPGTHKNSLGMLGMHGTYEANMAMHEADLIFGIGVRFDDR-TTNNLEKYC 297

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
             +  +  D +P ++  N      DL I G     +  ++  L  Q S      + Q   
Sbjct: 298 PNAKVMHIDIDPSSISKN---VKVDLPIVGSADKVLATMMGLLKEQGSSNDQDAITQWWE 354

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           E IQ+ + R     +T   ++   QV  TL  L +    +    G + M  A + +P + 
Sbjct: 355 E-IQVWRDRQCLAYETSPERIKPQQVIETLHKLTNGDAYVASDVGQHQM-FAALYYPFNK 412

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL  A+  K + PE +VV++ GD +   +  E+ TA++  + + I
Sbjct: 413 PRRWINSGGLGTMGFGLPAAMGVKFAMPEEEVVVVTGDGSIQMNIQELSTAMQYDIPVKI 472

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +DI  +G    + +S    +  + +  G     + T  +L    Q+
Sbjct: 473 INLNNRFLGMVKQWQDIIYQGRHSNSYMSSVPDFAAIAEAYGHVGIRIETPDQLEAGLQK 532

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+ +   K     +++ ++  E 
Sbjct: 533 ALDM---KDRLVFVDINVDETEH 552
>ref|XP_001160372.1| PREDICTED: 2-hydroxyphytanoyl-CoA lyase isoform 5 [Pan troglodytes]
          Length = 552

 Score =  627 bits (1617), Expect = e-178,   Method: Composition-based stats.
 Identities = 209/578 (36%), Positives = 307/578 (53%), Gaps = 57/578 (9%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
             +  +  AQ L+   ++ +FGIVGIP+ ++A      GIK+I  RNEQAA YAASA GY
Sbjct: 13  QVSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGY 72

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
           ++ +PGV L+V GPGLIHAL G+ N+  N WPLLVI GSS ++    G FQE  Q     
Sbjct: 73  LTSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQ----- 127

Query: 122 PFLKFTGKLTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPM 181
                               A+   I G  G  Y+D+PADF+     L+ N  +   +  
Sbjct: 128 --------------------AVRSSIYGRPGACYVDIPADFVN----LQVNVNSIKYMER 163

Query: 182 ILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPM 241
            ++P I   + S +     +I   K   ++I  G         I++LV  + LPFLPTPM
Sbjct: 164 CMSPPISMAETSAVCTAASVIRNAKQPLLIIGKGAAYAHAEESIKKLVEQYKLPFLPTPM 223

Query: 242 AKGIVPDSSPLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIFIQFDSNPE 301
            KG+VPD+ P  V +ARS+AL+ AD++++ GARLNWILHFG  P++  +  FIQ D   E
Sbjct: 224 GKGVVPDNHPYCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQPDVKFIQVDICAE 283

Query: 302 TLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKY---SGVKQEIREKIQLNQTRL 358
            LG+N       +++ G+I      L+EEL +  + W+Y   S   + +REK++ N+   
Sbjct: 284 ELGNN---VKPTVTLLGNIHAVTKQLLEELDK--TPWQYPPESKWWKTLREKMKSNEAAS 338

Query: 359 LRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTN 418
                 +   +NY  V+  ++  +      +V+EGANTMDI R       PR RLDAGT 
Sbjct: 339 KELASKKSLPMNYYTVFYHIQEQLPRD-CFVVSEGANTMDIGRTVLQNYLPRHRLDAGTF 397

Query: 419 ATMGIGLGYALACKASHPEL----DVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS 474
            TMG+GLG+A+A      +      ++ ++GDSAFGFS ME+ET  R  L ++++V+NN+
Sbjct: 398 GTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLPIILLVVNNN 457

Query: 475 GIYHG-----------EKDIEGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQ 523
           GIY G            +D    +PP  L  N  Y+ V    G   +FV T  EL +  +
Sbjct: 458 GIYQGFDTDTWKEMLKFQDATAVVPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQKSLR 517

Query: 524 QAVQLSRTKRETSVINVIIEP-GEQKQIAFAWQNKPRL 560
           Q++       + S+INV+IEP   +K   F W  +  +
Sbjct: 518 QSLA---DTTKPSLINVMIEPQATRKAQDFHWLTRSNM 552
>ref|ZP_01814076.1| acetolactate synthase III large subunit [Vibrionales bacterium
           SWAT-3]
 gb|EDK28548.1| acetolactate synthase III large subunit [Vibrionales bacterium
           SWAT-3]
          Length = 579

 Score =  627 bits (1617), Expect = e-178,   Method: Composition-based stats.
 Identities = 123/559 (22%), Positives = 244/559 (43%), Gaps = 25/559 (4%)

Query: 3   TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA--NGIKFIPCRNEQAASYAASAYG 60
            +  +   Q L + G++ +FG  G  ++ + D + A  + IK +  R+EQAA++ A  Y 
Sbjct: 10  LSGAEMVVQSLIEEGVEQIFGYPGGSVLDIYDALHAKTDEIKHVLVRHEQAATHMADGYT 69

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
             + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   + I    FQE D V + 
Sbjct: 70  RSTGKPGVVLVCSGPGATNTVTGIATAYMDSIPMIVISGNVPNNLIGNDAFQECDIVGVS 129

Query: 121 SPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNEL 179
            P +K +  +   ++I  + +KA      G  G   ID+P D +  +  L        ++
Sbjct: 130 RPIVKHSFLVKKAEDIPEVLKKAFYISTTGRPGPVVIDLPKDVLNPQIKLPYQYPETIKM 189

Query: 180 PMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPT 239
                P + G    +IKK ++ +L+ K   + +  G    +   ++ +L    NLP + T
Sbjct: 190 -RSYNPTVTG-HKGQIKKALKALLEAKKPVLYVGGGAVISEADQQLIKLAEALNLPVVST 247

Query: 240 PMAKGIVPDSSPLNVS-------SARSQALKIADIVLVLGARLNWILHFGTSPKWNSESI 292
            M  G  P +   ++           + A+  AD++  +G R +         K+   + 
Sbjct: 248 LMGLGAFPGTHKNSLGMLGMHGLYEANMAMHNADLIFGVGVRFDDR-TTNNLDKYCPNAK 306

Query: 293 FIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQ 352
            +  D +P ++  N      DL I G     + ++V  L  Q        ++    E I+
Sbjct: 307 IMHIDIDPSSISKN---VKVDLPIVGSAEKVLESMVNLLVEQGGSNDAEALESWWSE-IK 362

Query: 353 LNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRR 412
             Q R     +     +   QV   L  + +    +    G + M  A + +P + PRR 
Sbjct: 363 QWQDRNCLAYEKSSECIKPQQVIEALHKVTNGDAYVASDVGQHQM-FAALYYPFNKPRRW 421

Query: 413 LDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMN 472
           +++G   TMG GL   +  K + P+ +VV++ GD +   +  E+ TA++  + + I+ +N
Sbjct: 422 INSGGLGTMGFGLPAGMGVKFAKPDEEVVVVTGDGSIQMNIQELSTALQYNIPVKIINLN 481

Query: 473 NS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQL 528
           N   G+    +DI  +G    + +     +  + +  G     +++  EL    ++A+ +
Sbjct: 482 NRFLGMVKQWQDIVYQGRHSNSYMDSVPDFAAIAEAYGHVGMRISSPDELESGLEKALAM 541

Query: 529 SRTKRETSVINVIIEPGEQ 547
              K     +++ ++  E 
Sbjct: 542 ---KDRLVFVDISVDDTEH 557
>ref|YP_001476982.1| acetolactate synthase, large subunit, biosynthetic type [Serratia
           proteamaculans 568]
 gb|ABV39854.1| acetolactate synthase, large subunit, biosynthetic type [Serratia
           proteamaculans 568]
          Length = 572

 Score =  626 bits (1616), Expect = e-177,   Method: Composition-based stats.
 Identities = 131/569 (23%), Positives = 240/569 (42%), Gaps = 41/569 (7%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  I  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHILVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGEVGVVLVTSGPGATNAITGIATAYMDSIPMVVLSGQVPSSLIGYDAFQECDMVG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIE------YEKPLEG 171
           +  P +K +  +   ++I  I +KA      G  G   ID+P D +       Y  P + 
Sbjct: 121 ISRPVVKHSFLVKRTEDIPGILKKAFYLASTGRPGPVVIDLPKDIVGPAVRMPYAYPQDV 180

Query: 172 NDRTGNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNS--HEIRRLV 229
           + R+ N                +IK+ +  IL  K    ++ +G GA+ ++   E+  L 
Sbjct: 181 SMRSYN--------PTVQGHRGQIKRALHTILTAKKP--VMYVGGGAINSACDAELLELA 230

Query: 230 NTFNLPFLPTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFG 282
              NLP   T M  G  P +         ++ +   ++ +  +D++  +G R +      
Sbjct: 231 EKLNLPVTCTLMGLGAFPGTHRQSVGMLGMHGTYEANKTMHNSDVIFAVGVRFDDR-TTN 289

Query: 283 TSPKWNSESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSG 342
              K+   +  +  D +P ++     +  AD+ I GD    +T ++E L ++D    +  
Sbjct: 290 NLAKYCPNATVLHIDIDPTSISK---TVDADIPIVGDAKQVLTQMLELLAQEDKAQDHDA 346

Query: 343 VKQEIREKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARI 402
           ++    + I+  + R           +    V  TL  L      +    G + M  A +
Sbjct: 347 LRDWW-QAIEQWRARDCLGYDKNSGTIKPQAVIETLHRLTRGDAYVTSDVGQHQM-FAAL 404

Query: 403 SFPTDAPRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRC 462
            +P D PRR +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++ 
Sbjct: 405 YYPFDKPRRWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQY 464

Query: 463 QLALVIVVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISEL 518
            L +++V +NN   G+    +D+   G    + +     +  + +  G     + T  EL
Sbjct: 465 NLPVIVVNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHVGIAIRTPDEL 524

Query: 519 SRCFQQAVQLSRTKRETSVINVIIEPGEQ 547
                QA+     K     ++V ++  E 
Sbjct: 525 ESKLAQALA---EKERLVFVDVTVDETEH 550
>ref|NP_759633.1| acetolactate synthase 3 catalytic subunit [Vibrio vulnificus CMCP6]
 ref|NP_933288.1| acetolactate synthase 3 catalytic subunit [Vibrio vulnificus YJ016]
 gb|AAO09160.1|AE016799_58 Thiamine pyrophosphate-requiring enzymes ; COG0028 [Vibrio
           vulnificus CMCP6]
 dbj|BAC93259.1| thiamine pyrophosphate-requiring enzyme [Vibrio vulnificus YJ016]
          Length = 574

 Score =  626 bits (1615), Expect = e-177,   Method: Composition-based stats.
 Identities = 131/563 (23%), Positives = 239/563 (42%), Gaps = 27/563 (4%)

Query: 1   MT--TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA--NGIKFIPCRNEQAASYAA 56
           MT   +  +   Q L +  ++ +FG  G  ++ + D + A    IK +  R+EQAA++ A
Sbjct: 1   MTAMLSGAEMVVQSLIEENVEQIFGYPGGSVLDIYDALHAKTEQIKHVLVRHEQAATHMA 60

Query: 57  SAYGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQ 116
             Y   + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   S I    FQE D 
Sbjct: 61  DGYARATGKPGVVLVCSGPGATNTITGIATAYMDSIPMIVISGNVPNSLIGNDAFQECDI 120

Query: 117 VSLLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRT 175
           V +  P +K +  +   ++I    +KA      G  G   ID+P D +     L      
Sbjct: 121 VGVSRPVVKHSFLVKRAEDIPETIKKAFYIATTGRPGPVVIDLPKDVMNPLIKLP--YEY 178

Query: 176 GNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLP 235
              + M            +IKK ++ +L+ K   + I  G         I +L  T NLP
Sbjct: 179 PKSISMRSYKPTTSGHKGQIKKALKALLEAKKPVLYIGGGAIISGAHESILKLAETLNLP 238

Query: 236 FLPTPMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
            + T M  G  P +         ++     + A+  AD++  +G R +         K+ 
Sbjct: 239 VVSTLMGLGAFPGTHKNALGMLGMHGKYEANMAMHNADLIFGVGVRFDDR-TTNNLEKYC 297

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
             +  +  D +P ++  N      DL I G     +  +V  L  Q +      +     
Sbjct: 298 PNAKIMHIDIDPSSISKN---VKVDLPIVGSAEQVLETMVTLLEEQGAENDTQALASWWD 354

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           E I+  + R      T   ++   QV  TL  L +    +    G + M  A + +P + 
Sbjct: 355 E-IEGWKARDCLAYDTSSERIKPQQVIETLHKLTNGDAYVASDVGQHQM-FAALYYPFNK 412

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL   +  K + PE +VV++ GD +   +  E+ TA++  + + I
Sbjct: 413 PRRWINSGGLGTMGFGLPAGMGVKFAMPEEEVVVVTGDGSIQMNIQELSTAMQYDIPVKI 472

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +DI  +G    + +S    +  + +  G     + T  +L    ++
Sbjct: 473 INLNNRFLGMVKQWQDIIYQGRHSNSYMSSVPDFAAIAEAYGHVGIRIETPDQLESELKR 532

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+ +   K     +++ ++  E 
Sbjct: 533 ALDM---KDRLVFVDINVDETEH 552
>ref|YP_001607309.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis Angola]
 ref|ZP_02224048.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. F1991016]
 ref|ZP_02226386.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. IP275]
 ref|ZP_02229832.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. E1979001]
 ref|ZP_02237893.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. B42003004]
 ref|ZP_02306711.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. UG05-0454]
 ref|ZP_02313804.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. MG05-1020]
 ref|ZP_02318188.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Mediaevalis str. K1973002]
 gb|AAM87188.1|AE013966_5 acetolactate synthase III, large subunit [Yersinia pestis KIM]
 gb|AAS63794.1| acetolactate synthase isozyme III large subunit [Yersinia pestis
           biovar Microtus str. 91001]
 gb|ABX88215.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis Angola]
 gb|EDR32853.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. IP275]
 gb|EDR37128.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. F1991016]
 gb|EDR44574.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. E1979001]
 gb|EDR51084.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. B42003004]
 gb|EDR56209.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. MG05-1020]
 gb|EDR60644.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. UG05-0454]
 gb|EDR64341.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Mediaevalis str. K1973002]
          Length = 593

 Score =  625 bits (1614), Expect = e-177,   Method: Composition-based stats.
 Identities = 125/563 (22%), Positives = 237/563 (42%), Gaps = 26/563 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 19  MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 78

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 79  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGFDAFQECDMVG 138

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I M+ +KA      G  G   ID+P D +     +        
Sbjct: 139 ISRPVVKHSFLVKRTEDIPMVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKMPYAYPEQV 198

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNS--HEIRRLVNTFNLP 235
            L     P + G    +IK+ +Q I+  K    ++ +G GA+  +   E+  L    NLP
Sbjct: 199 SL-RSYNPTVQG-HRGQIKRALQTIMAAKRP--IMYVGGGAINAACHEELLILAEKLNLP 254

Query: 236 FLPTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
              + M  G  P +         ++ +   + A+   D++  +G R +         K+ 
Sbjct: 255 VTSSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYC 313

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
            ++  +  D +P ++     +  AD+ I GD    +T +++ L++      +  ++    
Sbjct: 314 PDATVLHIDIDPTSISK---TVTADIPIVGDAKQVLTQMLDLLSQVGCTQDFDSLRDWW- 369

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           + I+  +TR          ++    V   L  L      +    G + M  A + +P D 
Sbjct: 370 QSIEQWRTRNCLGYNKDSGKIKPQAVIEALHRLTKGDAYVTSDVGQHQM-FAALYYPFDK 428

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL  AL  K + P   VV + GD +   +  E+ TA++  L +++
Sbjct: 429 PRRWINSGGLGTMGFGLPAALGVKLALPNETVVCVTGDGSIQMNIQELSTALQYNLPVLV 488

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +D+   G    + +     +  + +  G     +NT  EL      
Sbjct: 489 LNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVAINTPDELESKLAD 548

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+           ++V ++  E 
Sbjct: 549 ALTQLSETNRLVFVDVTVDETEH 571
>ref|YP_944713.1| acetolactate synthase, large subunit, biosynthetic type
           [Psychromonas ingrahamii 37]
 gb|ABM05114.1| acetolactate synthase, large subunit [Psychromonas ingrahamii 37]
          Length = 574

 Score =  625 bits (1613), Expect = e-177,   Method: Composition-based stats.
 Identities = 126/561 (22%), Positives = 235/561 (41%), Gaps = 25/561 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADT-MVANGIKFIPCRNEQAASYAASA 58
           M   +  +   + LQ  GI+ +FG  G  ++ + D    ++ I+    R+EQAA + A A
Sbjct: 1   MEMLSGAEMVVRSLQDEGIEHIFGYPGGSVLDIYDAIFQSDKIEHYLVRHEQAAVHMADA 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + K G +L+  GPG  + + G+  +  +  PL+V++G    + I    FQE D + 
Sbjct: 61  YSRATGKVGCVLVTAGPGATNCITGLVTAYMDSIPLVVLSGQVPTNWIGDDAFQEADMIG 120

Query: 119 LLSPFLKFTGK-LTPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +    T ++I +  +KA      G  G   ID+P D                
Sbjct: 121 ISRPVVKHSFSCRTAEDIPIAIKKAFYIASTGRPGPVVIDLPKDVQSPLHKFPYEYPKSV 180

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
           EL     P + G    +IK+ +  +L  K     +  G      S ++  L    NLP  
Sbjct: 181 EL-RSYKPTLSG-HKGQIKRALAALLGAKKPVFYVGGGAIIANASKQVLELAEKLNLPVT 238

Query: 238 PTPMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            T M  G  P           ++ +   + ++  AD++   GAR +  +      K+   
Sbjct: 239 NTLMGLGAFPGEHKQFIGMLGMHGTYEANLSMHNADLIFSAGARFDDRVT-NNVDKFCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +Q D +P ++  N     ADL I G I + +  +++ L    +      +     ++
Sbjct: 298 AKIMQIDIDPTSISKN---IHADLPIVGSIEVVLQQMLDLLEETKATNDSESINAWW-DQ 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I   + +     +T    +   QV   L  +      +    G + M +A   +P   PR
Sbjct: 354 INEWRAKDCLAYQTSETHIKPQQVIQCLYKVTKGDAIVTSDVGQHQM-VAAQYYPFKEPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           + +++G   TMG GL  A+ CK + P+  VV + GD +   +  E+ T ++  + +VI++
Sbjct: 413 QWINSGGAGTMGFGLPAAMGCKIAFPDRPVVCVTGDGSIQMNIQELSTCMQYNIPVVILL 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    + +  +G    + +     +  + +        V+ I EL    ++A 
Sbjct: 473 LNNRSLGMVKQWQKMFYDGRQSHSYMDSVPDFVKLSEAYNHIGIKVDKIEELEPALERAF 532

Query: 527 QLSRTKRETSVINVIIEPGEQ 547
           +L   K     I+V I+P E 
Sbjct: 533 EL---KDRVVFIDVAIDPEEH 550
>ref|ZP_01986889.1| acetolactate synthase, large subunit, biosynthetic type [Vibrio
           harveyi HY01]
 gb|EDL68416.1| acetolactate synthase, large subunit, biosynthetic type [Vibrio
           harveyi HY01]
          Length = 574

 Score =  625 bits (1613), Expect = e-177,   Method: Composition-based stats.
 Identities = 132/563 (23%), Positives = 246/563 (43%), Gaps = 27/563 (4%)

Query: 1   MT--TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA--NGIKFIPCRNEQAASYAA 56
           MT   +  +   Q L +  ++ +FG  G  ++ + D + A  + IK +  R+EQAA++ A
Sbjct: 1   MTAMLSGAEMVVQSLIEESVEQIFGYPGGSVLDIYDALHAKTDQIKHVLVRHEQAATHMA 60

Query: 57  SAYGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQ 116
             Y   + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   + I    FQE D 
Sbjct: 61  DGYARATGKPGVVLVCSGPGATNTITGIATAYMDSIPMIVISGNVPNNLIGNDAFQECDI 120

Query: 117 VSLLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRT 175
           V +  P +K +  +   ++I    +KA      G  G   ID+P D +  +  L      
Sbjct: 121 VGVSRPVVKHSFLVKKAEDIPETIKKAFYISTTGRPGPVVIDLPKDILNPQIKLPYEYPE 180

Query: 176 GNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLP 235
              +     P   G    +IKK ++ +++ K   + I  G         I+ L +  NLP
Sbjct: 181 SISM-RSYKPTTSG-HKGQIKKALKSLVEAKKPVLYIGGGAVISGAHEHIQALSDELNLP 238

Query: 236 FLPTPMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
            + T M  G  P +         ++ +   + A+  AD++  +G R +         K+ 
Sbjct: 239 VVSTLMGLGAFPGTHKNSLGMLGMHGTYEANMAMHEADLIFGIGVRFDDR-TTNNLEKYC 297

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
             +  +  D +P ++  N      DL I G     +  ++  L  Q S      + Q   
Sbjct: 298 PNAKVMHIDIDPSSISKN---VKVDLPIVGSADKVLATMMGLLKEQGSSNDQDAITQWWE 354

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           E IQ+ + R     +T   ++   QV  TL  L +    +    G + M  A + +P + 
Sbjct: 355 E-IQVWRDRQCLAYETSPERIKPQQVIETLHKLTNGDAYVASDVGQHQM-FAALYYPFNK 412

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL   +  K + PE +VV++ GD +   +  E+ TA++  + + I
Sbjct: 413 PRRWINSGGLGTMGFGLPAGMGVKFAMPEEEVVVVTGDGSIQMNIQELSTAMQYDIPVKI 472

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +DI  +G    + +S    +  + +  G     + T  +L    Q+
Sbjct: 473 INLNNRFLGMVKQWQDIIYQGRHSNSYMSSVPDFAAIAEAYGHVGIRIETPDQLEAGLQK 532

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+ +   K     +++ ++  E 
Sbjct: 533 ALDM---KDRLVFVDINVDETEH 552
>ref|ZP_01161985.1| acetolactate synthase III large subunit [Photobacterium sp. SKA34]
 gb|EAR54292.1| acetolactate synthase III large subunit [Photobacterium sp. SKA34]
          Length = 572

 Score =  625 bits (1613), Expect = e-177,   Method: Composition-based stats.
 Identities = 122/562 (21%), Positives = 243/562 (43%), Gaps = 27/562 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTM-VANGIKFIPCRNEQAASYAASA 58
           M   +      + +   G+  +FG  G  ++ + D +   + I+ +  R+EQAA + A  
Sbjct: 1   MEMLSGADMIVRSMIDQGVKHIFGYPGGSVLDIYDALHEKSDIEHVLVRHEQAAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   +   GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGDVGVVLVTSGPGATNAITGIATAYMDSIPMVVLSGQVMSSLIGNDAFQECDMVG 120

Query: 119 LLSPFLKFTGKLT-PDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +T P++I  I +KA      G  G   +D+P D +    P E       
Sbjct: 121 ISRPVVKHSFLVTKPEDIPEIIKKAFYIASTGRPGPVVVDIPKDMLN---PAEAYPYQYP 177

Query: 178 E-LPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPF 236
           E + +            +IK+ V+ +L  K   + +  G      S ++  L  + N+P 
Sbjct: 178 ESISLRSYNPTTQGHKGQIKRGVKALLSAKKPVLYVGGGAIMSSCSEQLIELAESLNIPV 237

Query: 237 LPTPMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNS 289
           + T M  G  P S         ++ +   + A+  AD++  +G R +         K+  
Sbjct: 238 VNTLMGLGAFPGSHKQCLGMLGMHGTYEANMAMHNADLIFGIGVRFDDR-TTNNLEKYCP 296

Query: 290 ESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIRE 349
           ++  +  D +P ++     +  AD+ I G     + ++++ L   +       + Q   +
Sbjct: 297 DATIMHIDIDPSSISK---TVSADIPIVGSADTVLNSMLKLLKEHEVKNDQQEIAQWW-Q 352

Query: 350 KIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAP 409
            I+  + R      T   ++   QV   L  L +    +    G + M  A + +P D P
Sbjct: 353 SIESWRERECLSYDTDSDRIKPQQVIEVLHRLTNGEAYVSSDVGQHQM-FAALYYPFDKP 411

Query: 410 RRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIV 469
           RR +++G   TMG GL  A+  K + P+ +VV + GD +   +  E+ TA++  + + I+
Sbjct: 412 RRWINSGGLGTMGFGLPAAMGVKFALPDAEVVCVTGDGSIQMNIQELSTALQYDIPVKII 471

Query: 470 VMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQA 525
            +NN   G+    +D+  +G    + +     +  + +  G     ++  ++L    ++A
Sbjct: 472 NLNNRFLGMVKQWQDMIYQGRHSHSYMDSVPDFAAIAEAYGHVGVRISDPNKLESELEKA 531

Query: 526 VQLSRTKRETSVINVIIEPGEQ 547
           + L   K +   I++ ++  E 
Sbjct: 532 LAL---KDKLVFIDISVDETEH 550
>ref|ZP_01474203.1| hypothetical protein VEx2w_02003241 [Vibrio sp. Ex25]
 gb|EDN56569.1| acetolactate synthase, large subunit, biosynthetic type [Vibrio sp.
           Ex25]
          Length = 574

 Score =  625 bits (1612), Expect = e-177,   Method: Composition-based stats.
 Identities = 130/563 (23%), Positives = 244/563 (43%), Gaps = 27/563 (4%)

Query: 1   MT--TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA--NGIKFIPCRNEQAASYAA 56
           MT   +  +   Q L +  ++ +FG  G  ++ + D + A  + IK +  R+EQAA++ A
Sbjct: 1   MTAMLSGAEMVVQSLIEEHVEQIFGYPGGSVLDIYDALHAKTDQIKHVLVRHEQAATHMA 60

Query: 57  SAYGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQ 116
             Y   + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   S I    FQE D 
Sbjct: 61  DGYARATGKPGVVLVCSGPGATNTITGIATAYMDSIPMIVISGNVPNSLIGNDAFQECDI 120

Query: 117 VSLLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRT 175
           V +  P +K +  +   ++I    +KA      G  G   ID+P D +  +  L    + 
Sbjct: 121 VGVSRPVVKHSFLVKKAEDIPETIKKAFYIATTGRPGPVVIDLPKDVMNPQIKLP--YQY 178

Query: 176 GNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLP 235
              L M            +IKK ++ +L+ K   + I  G         I  L +  NLP
Sbjct: 179 PETLSMRSYKPTTSGHKGQIKKALKSLLEAKKPVLYIGGGAVISGAHEHILELSDKLNLP 238

Query: 236 FLPTPMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
            + T M  G  P +         ++ +   + A+  AD++  +G R +         K+ 
Sbjct: 239 VVSTLMGLGAFPGTHKNSLGMLGMHGTYEANMAMHEADLIFGIGVRFDDR-TTNNLEKYC 297

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
             +  +  D +P ++  N      DL I G     +T ++  L  Q+       +     
Sbjct: 298 PNAKVMHIDIDPSSISKN---VKVDLPIVGSAEKVLTTMLGLLAEQEGGNDEDAITAWW- 353

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           + IQ+ + R     +    ++   QV  TL  L +    +    G + M  A + +P + 
Sbjct: 354 DDIQVWRDRNCLAYEKSPERIKPQQVIETLHKLTNGDAYVASDVGQHQM-FAALYYPFNK 412

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL   +  K + P+ +VV++ GD +   +  E+ TA++  + + I
Sbjct: 413 PRRWINSGGLGTMGFGLPAGMGVKFAMPQEEVVVVTGDGSIQMNIQELSTAMQYDIPVKI 472

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +DI  +G    + +S    +  + +  G     + T  +L    Q+
Sbjct: 473 INLNNRFLGMVKQWQDIIYQGRHSNSYMSSVPDFAAIAEAYGHVGIRIETPDQLEEGLQK 532

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+ +   K     +++ ++  E 
Sbjct: 533 ALDM---KDRLVFVDINVDETEH 552
>ref|ZP_00992427.1| acetolactate synthase III large subunit [Vibrio splendidus 12B01]
 gb|EAP92573.1| acetolactate synthase III large subunit [Vibrio splendidus 12B01]
          Length = 585

 Score =  624 bits (1611), Expect = e-177,   Method: Composition-based stats.
 Identities = 127/565 (22%), Positives = 243/565 (43%), Gaps = 37/565 (6%)

Query: 3   TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVAN--GIKFIPCRNEQAASYAASAYG 60
            +  +   Q L + G++ +FG  G  ++ + D + A    IK +  R+EQAA++ A  Y 
Sbjct: 16  LSGAEMVVQSLIEEGVEQIFGYPGGSVLDIYDALHAKTAEIKHVLVRHEQAATHMADGYT 75

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
             + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   S I    FQE D V + 
Sbjct: 76  RSTGKPGVVLVCSGPGATNTVTGIATAYMDSIPMIVISGNVPNSLIGNDAFQECDIVGVS 135

Query: 121 SPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIE------YEKPLEGND 173
            P +K +  +   ++I  + +KA      G  G   ID+P D +       YE P     
Sbjct: 136 RPIVKHSFLVKKAEDIPEVVKKAFYISTTGRPGPVVIDLPKDILNPQIKLPYEYPETIKM 195

Query: 174 RTGNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFN 233
           R+ N                +IKK ++ +L+ K   + +  G    +    + +L    N
Sbjct: 196 RSYN--------PTVTGHKGQIKKALKALLEAKKPVLYVGGGAVISEADKPLLKLAEALN 247

Query: 234 LPFLPTPMAKGIVPDSSPLNVS-------SARSQALKIADIVLVLGARLNWILHFGTSPK 286
           LP + T M  G  P +   ++           + A+  AD++  +G R +         K
Sbjct: 248 LPVVSTLMGLGAFPGTHKNSLGMLGMHGLYEANMAMHNADLIFGIGVRFDDR-TTNNLDK 306

Query: 287 WNSESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQE 346
           +  ++  +  D +P ++  N      DL I G     + ++V  L  Q      +   + 
Sbjct: 307 YCPDAKIMHIDIDPSSISKN---VKVDLPIVGSAEKVLESMVNLLIEQGGTND-ADAMES 362

Query: 347 IREKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPT 406
              +I+  Q R          ++   QV  TL  + +    +    G + M  A + +P 
Sbjct: 363 WWSEIKQWQERDCLAYDKTSGRIKPQQVIETLHKVTNGDAYVASDVGQHQM-FAALYYPF 421

Query: 407 DAPRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLAL 466
           D PRR +++G   TMG GL   +  K + P+ +VV++ GD +   +  E+ TA++  + +
Sbjct: 422 DKPRRWINSGGLGTMGFGLPAGMGVKFAKPDEEVVIVTGDGSIQMNIQELSTALQYNIPV 481

Query: 467 VIVVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
            I+ +NN   G+    +DI  +G    + +     +  + +  G     +++  EL    
Sbjct: 482 KIINLNNRFLGMVKQWQDIVYQGRYSNSYMDSVPDFAAIAEAYGHVGMRISSPDELESGL 541

Query: 523 QQAVQLSRTKRETSVINVIIEPGEQ 547
           ++A+ +   K     +++ ++  E 
Sbjct: 542 EKALAM---KDRLVFVDISVDDTEH 563
>ref|NP_404181.1| acetolactate synthase 3 catalytic subunit [Yersinia pestis CO92]
 ref|YP_069216.1| acetolactate synthase 3 catalytic subunit [Yersinia
           pseudotuberculosis IP 32953]
 ref|YP_653467.1| acetolactate synthase 3 catalytic subunit [Yersinia pestis Antiqua]
 ref|YP_646339.1| acetolactate synthase 3 catalytic subunit [Yersinia pestis
           Nepal516]
 ref|ZP_01917153.1| acetolactate synthase isozyme III large subunit [Yersinia pestis
           CA88-4125]
 ref|YP_001402358.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis IP 31758]
 ref|NP_670937.2| acetolactate synthase 3 catalytic subunit [Yersinia pestis KIM]
 ref|NP_994917.2| acetolactate synthase 3 catalytic subunit [Yersinia pestis biovar
           Microtus str. 91001]
 ref|YP_001722251.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis YPIII]
 ref|YP_001871143.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis PB1/+]
 emb|CAH19915.1| acetolactate synthase III, valine sensitive, large subunit FAD and
           thiamine PPi binding [Yersinia pseudotuberculosis IP
           32953]
 gb|ABG16739.1| acetolactate synthase, large subunit [Yersinia pestis Nepal516]
 gb|ABG15522.1| acetolactate synthase, large subunit [Yersinia pestis Antiqua]
 emb|CAL19219.1| acetolactate synthase isozyme III large subunit [Yersinia pestis
           CO92]
 gb|EDM39910.1| acetolactate synthase isozyme III large subunit [Yersinia pestis
           CA88-4125]
 gb|ABS46825.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis IP 31758]
 gb|ACA69798.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis YPIII]
 gb|ACC87686.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis PB1/+]
          Length = 575

 Score =  624 bits (1611), Expect = e-177,   Method: Composition-based stats.
 Identities = 125/563 (22%), Positives = 237/563 (42%), Gaps = 26/563 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGFDAFQECDMVG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I M+ +KA      G  G   ID+P D +     +        
Sbjct: 121 ISRPVVKHSFLVKRTEDIPMVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKMPYAYPEQV 180

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNS--HEIRRLVNTFNLP 235
            L     P + G    +IK+ +Q I+  K    ++ +G GA+  +   E+  L    NLP
Sbjct: 181 SL-RSYNPTVQG-HRGQIKRALQTIMAAKRP--IMYVGGGAINAACHEELLILAEKLNLP 236

Query: 236 FLPTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
              + M  G  P +         ++ +   + A+   D++  +G R +         K+ 
Sbjct: 237 VTSSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYC 295

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
            ++  +  D +P ++     +  AD+ I GD    +T +++ L++      +  ++    
Sbjct: 296 PDATVLHIDIDPTSISK---TVTADIPIVGDAKQVLTQMLDLLSQVGCTQDFDSLRDWW- 351

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           + I+  +TR          ++    V   L  L      +    G + M  A + +P D 
Sbjct: 352 QSIEQWRTRNCLGYNKDSGKIKPQAVIEALHRLTKGDAYVTSDVGQHQM-FAALYYPFDK 410

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL  AL  K + P   VV + GD +   +  E+ TA++  L +++
Sbjct: 411 PRRWINSGGLGTMGFGLPAALGVKLALPNETVVCVTGDGSIQMNIQELSTALQYNLPVLV 470

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +D+   G    + +     +  + +  G     +NT  EL      
Sbjct: 471 LNLNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVAINTPDELESKLAD 530

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+           ++V ++  E 
Sbjct: 531 ALTQLSETNRLVFVDVTVDETEH 553
>ref|ZP_01066405.1| acetolactate synthase III large subunit [Vibrio sp. MED222]
 gb|EAQ52250.1| acetolactate synthase III large subunit [Vibrio sp. MED222]
          Length = 585

 Score =  624 bits (1611), Expect = e-177,   Method: Composition-based stats.
 Identities = 127/565 (22%), Positives = 243/565 (43%), Gaps = 37/565 (6%)

Query: 3   TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVAN--GIKFIPCRNEQAASYAASAYG 60
            +  +   Q L + G++ +FG  G  ++ + D + A    IK +  R+EQAA++ A  Y 
Sbjct: 16  LSGAEMVVQSLIEEGVEQIFGYPGGSVLDIYDALHAKTAEIKHVLVRHEQAATHMADGYT 75

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
             + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   + I    FQE D V + 
Sbjct: 76  RSTGKPGVVLVCSGPGATNTVTGIATAYMDSIPMIVISGNVPNNLIGNDAFQECDIVGVS 135

Query: 121 SPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIE------YEKPLEGND 173
            P +K +  +   ++I  + +KA      G  G   ID+P D +       YE P     
Sbjct: 136 RPIVKHSFLVKKAEDIPEVVKKAFYISTTGRPGPVVIDLPKDILNPQIKLPYEYPETIKM 195

Query: 174 RTGNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFN 233
           R+ N                +IKK ++ +L+ K   + +  G    +    + +L    N
Sbjct: 196 RSYN--------PTVTGHKGQIKKALKALLEAKKPVLYVGGGAVISEADKPLLKLAEALN 247

Query: 234 LPFLPTPMAKGIVPDSSPLNVS-------SARSQALKIADIVLVLGARLNWILHFGTSPK 286
           LP + T M  G  P +   ++           + A+  AD++  +G R +         K
Sbjct: 248 LPVVSTLMGLGAFPGTHKNSLGMLGMHGLYEANMAMHNADLIFGIGVRFDDR-TTNNLDK 306

Query: 287 WNSESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQE 346
           +  ++  +  D +P ++  N      DL I G     + ++V  L  Q        ++  
Sbjct: 307 YCPDAKIMHIDIDPSSISKN---VKVDLPIVGSAEKVLESMVNLLIEQGGTNDAEAMESW 363

Query: 347 IREKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPT 406
             E I+  Q R          ++   QV  TL  + +    +    G + M  A + +P 
Sbjct: 364 WSE-IKQWQERDCLAYDKTSGRIKPQQVIETLHKVTNGDAYVASDVGQHQM-FAALYYPF 421

Query: 407 DAPRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLAL 466
           D PRR +++G   TMG GL   +  K + P+ +VV++ GD +   +  E+ TA++  + +
Sbjct: 422 DKPRRWINSGGLGTMGFGLPAGMGVKFAKPDEEVVIVTGDGSIQMNIQELSTALQYNIPV 481

Query: 467 VIVVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCF 522
            I+ +NN   G+    +DI  +G    + +     +  + +  G     +++  EL    
Sbjct: 482 KIINLNNRFLGMVKQWQDIVYQGRYSNSYMDSVPDFAAIAEAYGHVGMRISSPDELESGL 541

Query: 523 QQAVQLSRTKRETSVINVIIEPGEQ 547
           ++A+ +   K     +++ ++  E 
Sbjct: 542 EKALAM---KDRLVFVDISVDDTEH 563
>ref|ZP_02196570.1| acetolactate synthase III large subunit [Vibrio campbellii AND4]
 gb|EDP58387.1| acetolactate synthase III large subunit [Vibrio campbellii AND4]
          Length = 574

 Score =  624 bits (1610), Expect = e-177,   Method: Composition-based stats.
 Identities = 133/563 (23%), Positives = 247/563 (43%), Gaps = 27/563 (4%)

Query: 1   MT--TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA--NGIKFIPCRNEQAASYAA 56
           MT   +  +   Q L +  ++ +FG  G  ++ + D + A  + IK +  R+EQAA++ A
Sbjct: 1   MTAMLSGAEMVVQSLIEESVEQIFGYPGGSVLDIYDALHAKTDQIKHVLVRHEQAATHMA 60

Query: 57  SAYGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQ 116
             Y   + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   + I    FQE D 
Sbjct: 61  DGYARATGKPGVVLVCSGPGATNTITGIATAYMDSIPMIVISGNVPNNLIGNDAFQECDI 120

Query: 117 VSLLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRT 175
           V +  P +K +  +   ++I    +KA      G  G   ID+P D +  +  L   +  
Sbjct: 121 VGVSRPVVKHSFLVKKAEDIPETIKKAFYISTTGRPGPVVIDLPKDILNPQIKL-PYEYP 179

Query: 176 GNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLP 235
            N       P   G    +IKK ++ +++ K   + I  G         I+ L +  NLP
Sbjct: 180 KNISMRSYKPTTSG-HKGQIKKALKALVEAKKPVLYIGGGAIISGAHEHIQTLSDELNLP 238

Query: 236 FLPTPMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWN 288
            + T M  G  P +         ++ +   + A+  AD++  +G R +         K+ 
Sbjct: 239 VVSTLMGLGAFPGTHKNSLGMLGMHGTYEANMAMHEADLIFGIGVRFDDR-TTNNLEKYC 297

Query: 289 SESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIR 348
             +  +  D +P ++  N      DL I G     +  +V  L  Q+       + Q   
Sbjct: 298 PNAKIMHIDIDPSSISKN---VKVDLPIVGSAEKVLATMVGLLNEQNGNNDAQAIAQWWE 354

Query: 349 EKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDA 408
           E IQ+ + R     +T   ++   QV  TL  L +    +    G + M  A + +P + 
Sbjct: 355 E-IQVWRERECLAYETSTERIKPQQVMQTLHKLTNGDAYVASDVGQHQM-FAALYYPFNK 412

Query: 409 PRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVI 468
           PRR +++G   TMG GL   +  K + PE +VV++ GD +   +  E+ TA++  + + I
Sbjct: 413 PRRWINSGGLGTMGFGLPAGMGVKFAMPEEEVVVVTGDGSIQMNIQELSTAMQYDIPVKI 472

Query: 469 VVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQ 524
           + +NN   G+    +DI  +G    + +S    +  + +  G     + T  +L    Q+
Sbjct: 473 INLNNRFLGMVKQWQDIIYQGRHSNSYMSSVPDFAAIAEAYGHVGIRIETPDQLEAGLQK 532

Query: 525 AVQLSRTKRETSVINVIIEPGEQ 547
           A+ +   K     +++ ++  E 
Sbjct: 533 ALDM---KDRLVFVDINVDETEH 552
>ref|ZP_02179310.1| acetolactate synthase large subunit [Hydrogenivirga sp. 128-5-R1-1]
 gb|EDP73924.1| acetolactate synthase large subunit [Hydrogenivirga sp. 128-5-R1-1]
          Length = 567

 Score =  623 bits (1608), Expect = e-176,   Method: Composition-based stats.
 Identities = 118/558 (21%), Positives = 237/558 (42%), Gaps = 22/558 (3%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGY 61
                     +L +  +DTVFG+ G  I+++ D +     K I  R+E AA + A  Y  
Sbjct: 3   KKRGADIVVDVLIEEKVDTVFGLPGGAIMEVYDALFNAPFKNILARHELAACHMADGYAR 62

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
            + K GV++   GPG  + + G+  +  +  PL+ I G      I    FQE D   +  
Sbjct: 63  ATGKVGVVMATSGPGATNLVTGLATAHMDSVPLVAITGQVPTHYIGTDAFQEADVTGITR 122

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
           P  K    +T   ++ +I ++A      G  G   +D+P D  +     +       E  
Sbjct: 123 PVTKHNFLVTDIKDLALILREAFYIARTGRPGPVLVDIPKDITQQVYDYKMPTLKDVEEA 182

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
           +         + ++IKK  +LI Q K   + +  G  A +   E+ +L     +P   T 
Sbjct: 183 LPGYKPHYEGNIAQIKKAAKLIRQAKRPVLYVGGGAVAAEAQEELVKLAEMAKIPVTTTL 242

Query: 241 MAKGIVPDSSPL-------NVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIF 293
           M KG  P+  PL       + +   + A+  +D+++ +G+R +  +  G   ++  E+  
Sbjct: 243 MGKGAFPEDHPLALHMLGMHGTYYANMAVYNSDLLIAVGSRFDDRVT-GKIDEFAPEAKI 301

Query: 294 IQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQL 353
           I  D +P ++     +   D+ I GD+   +  L++EL R+   W  +  ++   + I+ 
Sbjct: 302 IHIDIDPASISK---TINVDVPIVGDVKKVLQKLIKELERKPVEWDEA--RESWIKLIEK 356

Query: 354 NQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRL 413
            +         +   +    V   +  +      I    G + M  A + +    PR+ +
Sbjct: 357 WKIEHPLTYDRKSKIIKPEYVVEEIYNITKGEAIITAGVGQHQMW-AAMFYKYKFPRQFI 415

Query: 414 DAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
           ++G   TMG G   A+  K + P+ +V+ I+GD +F  +  +I TAV+ ++ + + ++NN
Sbjct: 416 NSGGLGTMGFGFPAAVGAKIARPDKEVIAIEGDGSFLMNIQDIATAVQYRVPVKVAILNN 475

Query: 474 S--GIYHGEKDIEGD--LPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLS 529
              G+    +++  D       LS    +  + +  GA        SE+ +  ++A+ ++
Sbjct: 476 EFLGMVRQWQELFYDSRYSSVCLSTQPDFVKLAESFGAVGLRATKPSEVKKVLKEAMSIN 535

Query: 530 RTKRETSVINVIIEPGEQ 547
                  +++  ++  E 
Sbjct: 536 ---DRPVIMDFAVDREEN 550
>ref|YP_001906687.1| Acetolactate synthase isozyme III large subunit [Erwinia
           tasmaniensis]
 emb|CAO95789.1| Acetolactate synthase isozyme III large subunit [Erwinia
           tasmaniensis]
          Length = 574

 Score =  623 bits (1607), Expect = e-176,   Method: Composition-based stats.
 Identities = 123/569 (21%), Positives = 241/569 (42%), Gaps = 39/569 (6%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    G+  I  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALQTVGGVDHILVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   +   GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGDVGVVLVTSGPGATNAITGIATAYMDSIPMVVLSGQVMSSLIGYDAFQECDMVG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIE------YEKPLEG 171
           +  P +K +  +   ++I  + +KA      G  G   +D+P D +       Y  P E 
Sbjct: 121 ISRPVVKHSFMVKRAEDIPTVMKKAFWLAASGRPGPVVVDLPKDMMNPANKLPYVWPDEV 180

Query: 172 NDRTGNELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNS--HEIRRLV 229
           + R+ N                +IK+ +Q +L  KN   +I  G G +  +   E+R+L 
Sbjct: 181 SMRSYN--------PTTQGHKGQIKRALQTLLAAKNP--VIYAGGGVINAACHDELRQLA 230

Query: 230 NTFNLPFLPTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFG 282
            T N+P   + M  G  P +         ++ +   +  +  +D++  +G R +      
Sbjct: 231 ETLNVPVTTSLMGLGAFPGTHHQCLGMLGMHGTYEANMTMHHSDVIFAVGVRFDDR-TTN 289

Query: 283 TSPKWNSESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSG 342
              K+   +  +  D +P ++     +  AD+ I GD    +  ++E L +  +   +  
Sbjct: 290 NLAKYCPNATVLHIDIDPTSISK---TIAADVPIVGDAKQVLQQMLELLGQDPARQDFDA 346

Query: 343 VKQEIREKIQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARI 402
           ++    + I+  ++R   +      ++    V  T+  L      +    G + M  A +
Sbjct: 347 LRDWW-QSIERWRSRHCLEFDRTSDKIKPQAVIETICRLTKGDAYVTSDVGQHQM-FAAL 404

Query: 403 SFPTDAPRRRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRC 462
            +  D PRR +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++ 
Sbjct: 405 YYQFDKPRRWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQY 464

Query: 463 QLALVIVVMNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISEL 518
            + ++++ +NN   G+    +D+   G    + +     +  + +  G     V    EL
Sbjct: 465 GIPVLVLNLNNRVLGMVKQWQDMIYSGRHSQSYMESLPDFVRLAEAYGHVGISVTRPDEL 524

Query: 519 SRCFQQAVQLSRTKRETSVINVIIEPGEQ 547
               +QA++    K     +++ ++  E 
Sbjct: 525 EAKLEQALE-QLAKNRLVFVDINVDDSEH 552
Searching..................................................done Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

ref|YP_344503.1|  Acetolactate synthase, large subunit, bios...   899   0.0  
ref|YP_114688.1|  acetolactate synthase, large subunit, bios...   895   0.0  
ref|ZP_00831646.1|  COG0028: Thiamine pyrophosphate-requirin...   895   0.0  
ref|ZP_00822285.1|  COG0028: Thiamine pyrophosphate-requirin...   893   0.0  
ref|ZP_00825910.1|  COG0028: Thiamine pyrophosphate-requirin...   892   0.0  
ref|ZP_02462916.1|  acetolactate synthase 3 catalytic subuni...   892   0.0  
ref|ZP_00833010.1|  COG0028: Thiamine pyrophosphate-requirin...   891   0.0  
ref|YP_295170.1|  acetolactate synthase 3 catalytic subunit ...   891   0.0  
ref|YP_001476982.1|  acetolactate synthase, large subunit, b...   891   0.0  
ref|ZP_02355077.1|  acetolactate synthase 3 catalytic subuni...   890   0.0  
ref|YP_001005008.1|  acetolactate synthase 3 catalytic subun...   889   0.0  
ref|YP_583066.1|  acetolactate synthase 3 catalytic subunit ...   889   0.0  
ref|ZP_02362280.1|  acetolactate synthase 3 catalytic subuni...   889   0.0  
ref|YP_107818.1|  acetolactate synthase 3 catalytic subunit ...   886   0.0  
ref|YP_725545.1|  acetolactate synthase 3 catalytic subunit ...   886   0.0  
gb|EDK58417.1|  acetolactate synthase, large subunit, biosyn...   886   0.0  
ref|YP_103451.1|  acetolactate synthase 3 catalytic subunit ...   886   0.0  
ref|YP_001607309.1|  acetolactate synthase, large subunit, b...   886   0.0  
ref|YP_441599.1|  acetolactate synthase 3 catalytic subunit ...   885   0.0  
ref|ZP_01161985.1|  acetolactate synthase III large subunit ...   885   0.0  
ref|YP_927893.1|  acetolactate synthase 3 catalytic subunit ...   885   0.0  
ref|YP_001906687.1|  Acetolactate synthase isozyme III large...   885   0.0  
ref|NP_404181.1|  acetolactate synthase 3 catalytic subunit ...   884   0.0  
ref|ZP_01770640.1|  acetolactate synthase, large subunit, bi...   884   0.0  
ref|ZP_01236581.1|  acetolactate synthase III large subunit ...   884   0.0  
ref|ZP_03831127.1|  acetolactate synthase 3 catalytic subuni...   883   0.0  
ref|YP_934657.1|  acetolactate synthase [Azoarcus sp. BH72] ...   883   0.0  
ref|YP_001791923.1|  acetolactate synthase, large subunit, b...   883   0.0  
ref|YP_001366575.1|  acetolactate synthase, large subunit, b...   882   0.0  
ref|YP_001894967.1|  acetolactate synthase, large subunit, b...   882   0.0  
ref|YP_001050748.1|  acetolactate synthase 3 catalytic subun...   882   0.0  
ref|YP_001554918.1|  acetolactate synthase, large subunit, b...   881   0.0  
ref|YP_051917.1|  acetolactate synthase 3 catalytic subunit ...   881   0.0  
ref|ZP_03827861.1|  acetolactate synthase 3 catalytic subuni...   881   0.0  
ref|YP_001164433.1|  acetolactate synthase 3 catalytic subun...   881   0.0  
ref|NP_520198.1|  acetolactate synthase 3 catalytic subunit ...   881   0.0  
gb|AAN78592.1|AE016755_92  Acetolactate synthase isozyme III...   880   0.0  
ref|YP_001742200.1|  acetolactate synthase, large subunit, i...   880   0.0  
ref|YP_002806680.1|  acetolactate synthase [Escherichia sp. ...   880   0.0  
ref|ZP_02844546.1|  acetolactate synthase, large subunit, bi...   880   0.0  
ref|NP_759633.1|  acetolactate synthase 3 catalytic subunit ...   879   0.0  
ref|ZP_01323079.1|  hypothetical protein BpseP_03003157 [Bur...   879   0.0  
ref|YP_001899794.1|  acetolactate synthase, large subunit, b...   879   0.0  
ref|ZP_01706659.1|  acetolactate synthase, large subunit, bi...   879   0.0  
ref|YP_851278.1|  acetolactate synthase 3 catalytic subunit ...   879   0.0  
ref|YP_001183658.1|  acetolactate synthase 3 catalytic subun...   879   0.0  
gb|ABU63575.1|  AHAS catalytic subunit [Klebsiella pneumoniae]    879   0.0  
ref|ZP_00440969.1|  COG0028: Thiamine pyrophosphate-requirin...   878   0.0  
ref|ZP_00943336.1|  Acetolactate synthase large subunit [Ral...   878   0.0  
ref|ZP_00923850.1|  COG0028: Thiamine pyrophosphate-requirin...   878   0.0  
ref|ZP_01219928.1|  acetolactate synthase III large subunit ...   878   0.0  
gb|AAG54381.1|AE005184_9  acetolactate synthase III, valine ...   878   0.0  
ref|ZP_02478424.1|  acetolactate synthase 3 catalytic subuni...   878   0.0  
ref|ZP_01116331.1|  acetolactate synthase III large subunit ...   878   0.0  
ref|ZP_02009737.1|  acetolactate synthase, large subunit, bi...   878   0.0  
ref|ZP_01915784.1|  acetolactate synthase large subunit [Lim...   878   0.0  
ref|YP_963262.1|  acetolactate synthase 3 catalytic subunit ...   878   0.0  
ref|YP_128659.1|  acetolactate synthase 3 catalytic subunit ...   878   0.0  
ref|ZP_00715653.1|  COG0028: Thiamine pyrophosphate-requirin...   878   0.0  
ref|ZP_02961406.1|  hypothetical protein PROSTU_03434 [Provi...   878   0.0  
ref|YP_390904.1|  acetolactate synthase, large subunit, bios...   877   0.0  
ref|NP_930874.1|  acetolactate synthase 3 catalytic subunit ...   877   0.0  
ref|AP_000741.1|  acetolactate synthase III, large subunit [...   877   0.0  
ref|ZP_01814076.1|  acetolactate synthase III large subunit ...   877   0.0  
dbj|BAB33504.1|  putative acetolactate synthase III large su...   876   0.0  
ref|ZP_00720987.1|  COG0028: Thiamine pyrophosphate-requirin...   876   0.0  
ref|ZP_00718693.1|  COG0028: Thiamine pyrophosphate-requirin...   876   0.0  
ref|YP_205646.1|  acetolactate synthase III, large subunit [...   876   0.0  
ref|NP_752048.2|  acetolactate synthase 3 catalytic subunit ...   876   0.0  
ref|YP_309114.1|  acetolactate synthase 3 catalytic subunit ...   876   0.0  
ref|ZP_00727763.1|  COG0028: Thiamine pyrophosphate-requirin...   876   0.0  
gb|ABO32786.1|  IlvI [Xenorhabdus nematophila]                    875   0.0  
gb|ABU62921.1|  catalytic subunit protein [Klebsiella pneumo...   875   0.0  
ref|YP_406628.1|  acetolactate synthase 3 catalytic subunit ...   875   0.0  
ref|YP_869904.1|  acetolactate synthase 3 catalytic subunit ...   875   0.0  
ref|ZP_03835233.1|  acetolactate synthase 3 catalytic subuni...   875   0.0  
ref|YP_001333772.1|  acetolactate synthase III large subunit...   875   0.0  
ref|ZP_01991840.1|  acetolactate synthase, large subunit, bi...   875   0.0  
ref|YP_737879.1|  acetolactate synthase 3 catalytic subunit ...   874   0.0  
ref|YP_733881.1|  acetolactate synthase 3 catalytic subunit ...   874   0.0  
ref|NP_308108.2|  acetolactate synthase 3 catalytic subunit ...   874   0.0  
ref|YP_539126.2|  acetolactate synthase 3 catalytic subunit ...   874   0.0  
ref|YP_855428.1|  acetolactate synthase, large subunit, bios...   874   0.0  
ref|YP_001474401.1|  acetolactate synthase, large subunit, b...   874   0.0  
ref|YP_944713.1|  acetolactate synthase, large subunit, bios...   874   0.0  
ref|YP_001099540.1|  acetolactate synthase III, valine-sensi...   874   0.0  
ref|YP_411174.1|  acetolactate synthase, large subunit, bios...   874   0.0  
ref|NP_796731.1|  acetolactate synthase 3 catalytic subunit ...   873   0.0  
ref|ZP_02159491.1|  acetolactate synthase III large subunit ...   873   0.0  
ref|YP_001454821.1|  hypothetical protein CKO_03301 [Citroba...   873   0.0  
ref|YP_001353840.1|  acetolactate synthase large subunit [Ja...   873   0.0  
ref|YP_001439319.1|  hypothetical protein ESA_03261 [Enterob...   873   0.0  
gb|EEH95023.1|  acetolactate synthase 3 catalytic subunit [C...   873   0.0  
gb|AAP15618.1|  acetolactate synthase III, large subunit [Sh...   873   0.0  
ref|ZP_01261609.1|  acetolactate synthase III large subunit ...   872   0.0  
ref|NP_717875.1|  acetolactate synthase 3 catalytic subunit ...   872   0.0  
ref|YP_001674604.1|  acetolactate synthase, large subunit, b...   872   0.0  
ref|ZP_00992427.1|  acetolactate synthase III large subunit ...   871   0.0  
ref|ZP_01066405.1|  acetolactate synthase III large subunit ...   871   0.0  
ref|NP_900256.1|  acetolactate synthase isozyme III, large s...   871   0.0  
gb|ABU63574.1|  AHAS catalytic subunit [Klebsiella pneumoniae]    871   0.0  
ref|YP_001143127.1|  acetolactate synthase isozyme III, larg...   871   0.0  
ref|YP_563127.1|  acetolactate synthase 3 catalytic subunit ...   871   0.0  
ref|YP_001444053.1|  acetolactate synthase III, large subuni...   871   0.0  
ref|YP_001155843.1|  acetolactate synthase, large subunit, b...   871   0.0  
ref|ZP_01474203.1|  hypothetical protein VEx2w_02003241 [Vib...   870   0.0  
ref|YP_001093901.1|  acetolactate synthase 3 catalytic subun...   870   0.0  
ref|YP_161069.1|  thiamine pyrophosphate dependent acetolact...   870   0.0  
ref|YP_787172.1|  acetolactate synthase isozyme III large su...   870   0.0  
ref|YP_001175362.1|  acetolactate synthase 3 catalytic subun...   869   0.0  
ref|NP_706030.3|  acetolactate synthase 3 catalytic subunit ...   869   0.0  
ref|YP_001760334.1|  acetolactate synthase, large subunit, b...   869   0.0  
ref|ZP_01166487.1|  acetolactate synthase large subunit [Oce...   868   0.0  
ref|ZP_01986889.1|  acetolactate synthase, large subunit, bi...   868   0.0  
ref|YP_001501768.1|  acetolactate synthase, large subunit, b...   868   0.0  
ref|YP_549138.1|  acetolactate synthase 3 catalytic subunit ...   868   0.0  
ref|NP_879604.1|  acetolactate synthase large subunit [Borde...   867   0.0  
ref|ZP_01983141.1|  acetolactate synthase III, large subunit...   867   0.0  
ref|YP_001279514.1|  acetolactate synthase 3 catalytic subun...   867   0.0  
ref|ZP_01389342.1|  acetolactate synthase, large subunit, bi...   866   0.0  
gb|EAY68336.1|  acetolactate synthase III large subunit [Bur...   866   0.0  
ref|YP_750317.1|  acetolactate synthase 3 catalytic subunit ...   866   0.0  
ref|YP_001579201.1|  acetolactate synthase, large subunit, b...   866   0.0  
ref|ZP_02348804.1|  acetolactate synthase 3 catalytic subuni...   866   0.0  
ref|YP_002794161.1|  IlvI [Laribacter hongkongensis HLHK9] >...   865   0.0  
ref|ZP_02196570.1|  acetolactate synthase III large subunit ...   865   0.0  
ref|YP_001630212.1|  acetolactate synthase large subunit [Bo...   865   0.0  
ref|ZP_01485182.1|  hypothetical protein VchoV5_02002207 [Vi...   865   0.0  
ref|ZP_01898340.1|  putative acetolactate synthase III, larg...   865   0.0  
ref|ZP_02698236.1|  acetolactate synthase 3 catalytic subuni...   864   0.0  
ref|ZP_02341028.1|  acetolactate synthase 3 catalytic subuni...   864   0.0  
ref|YP_001217983.1|  acetolactate synthase 3 catalytic subun...   864   0.0  
ref|NP_454728.1|  acetolactate synthase 3 catalytic subunit ...   864   0.0  
ref|YP_958165.1|  acetolactate synthase 3 catalytic subunit ...   864   0.0  
ref|YP_001232446.1|  acetolactate synthase, large subunit, b...   864   0.0  
ref|YP_436992.1|  acetolactate synthase 3 catalytic subunit ...   864   0.0  
ref|NP_232112.1|  acetolactate synthase 3 catalytic subunit ...   864   0.0  
ref|ZP_02344448.1|  acetolactate synthase 3 catalytic subuni...   864   0.0  
ref|YP_546227.1|  acetolactate synthase, large subunit, bios...   863   0.0  
ref|ZP_02653812.1|  acetolactate synthase 3 catalytic subuni...   863   0.0  
ref|ZP_02566175.1|  acetolactate synthase 3 catalytic subuni...   863   0.0  
ref|ZP_02562647.1|  acetolactate synthase 3 catalytic subuni...   863   0.0  
ref|ZP_02647746.1|  acetolactate synthase 3 catalytic subuni...   863   0.0  
ref|YP_692201.1|  acetolactate synthase 3 catalytic subunit ...   863   0.0  
ref|ZP_02676134.1|  acetolactate synthase 3 catalytic subuni...   863   0.0  
ref|YP_747479.1|  acetolactate synthase, large subunit, bios...   862   0.0  
ref|ZP_02684173.1|  acetolactate synthase 3 catalytic subuni...   862   0.0  
ref|YP_001350734.1|  acetolactate synthase, large subunit, b...   862   0.0  
ref|ZP_02702672.1|  acetolactate synthase 3 catalytic subuni...   862   0.0  
ref|ZP_00420009.1|  Acetolactate synthase, large subunit, bi...   861   0.0  
gb|EDN13953.1|  acetolactate synthase III, large subunit [Vi...   861   0.0  
ref|YP_524562.1|  acetolactate synthase 3 catalytic subunit ...   861   0.0  
ref|NP_841374.1|  Thiamine pyrophosphate dependent enzyme [N...   861   0.0  
ref|YP_215100.2|  acetolactate synthase 3 catalytic subunit ...   861   0.0  
ref|ZP_01482559.1|  hypothetical protein VchoR_02001517 [Vib...   861   0.0  
gb|EDN75307.1|  acetolactate synthase [Mannheimia haemolytic...   861   0.0  
ref|YP_986033.1|  acetolactate synthase 3 catalytic subunit ...   860   0.0  
ref|YP_369830.1|  acetolactate synthase 3 catalytic subunit ...   860   0.0  
ref|YP_001708120.1|  acetolactate synthase III, large subuni...   860   0.0  
ref|ZP_02902899.1|  acetolactate synthase, large subunit, is...   860   0.0  
ref|ZP_00987011.1|  COG0028: Thiamine pyrophosphate-requirin...   860   0.0  
ref|ZP_01617210.1|  acetolactate synthase III large subunit ...   859   0.0  
ref|YP_149463.1|  acetolactate synthase 3 catalytic subunit ...   859   0.0  
ref|NP_253384.1|  acetolactate synthase 3 catalytic subunit ...   859   0.0  
ref|YP_971450.1|  acetolactate synthase 3 catalytic subunit ...   859   0.0  
ref|YP_001120183.1|  acetolactate synthase 3 catalytic subun...   859   0.0  
ref|ZP_01521731.1|  acetolactate synthase, large subunit, bi...   859   0.0  
ref|YP_774193.1|  acetolactate synthase 3 catalytic subunit ...   859   0.0  
ref|ZP_00157121.1|  COG0028: Thiamine pyrophosphate-requirin...   859   0.0  
ref|NP_245807.1|  acetolactate synthase 3 catalytic subunit ...   859   0.0  
ref|NP_439730.1|  acetolactate synthase 3 catalytic subunit ...   858   0.0  
ref|ZP_02889174.1|  acetolactate synthase, large subunit, bi...   858   0.0  
ref|NP_790820.1|  acetolactate synthase, large subunit, bios...   858   0.0  
gb|ABF02354.1|  acetolactate synthase isozyme III large subu...   858   0.0  
ref|YP_557803.1|  acetolactate synthase 3 catalytic subunit ...   858   0.0  
ref|ZP_02905508.1|  acetolactate synthase, large subunit, bi...   858   0.0  
ref|YP_001290857.1|  acetolactate synthase 3 catalytic subun...   858   0.0  
ref|YP_350516.1|  acetolactate synthase 3 catalytic subunit ...   858   0.0  
ref|YP_001930430.1|  acetolactate synthase, large subunit, b...   858   0.0  
ref|ZP_00349598.1|  COG0028: Thiamine pyrophosphate-requirin...   858   0.0  
sp|Q9RQ65|ILVI_BUCSC  Acetolactate synthase large subunit (A...   858   0.0  
ref|YP_088511.1|  acetolactate synthase 3 catalytic subunit ...   858   0.0  
ref|YP_996517.1|  acetolactate synthase 3 catalytic subunit ...   858   0.0  
ref|YP_001808876.1|  acetolactate synthase, large subunit, b...   857   0.0  
gb|ABL09941.1|  IlvI [Pseudomonas aeruginosa] >gi|118640848|...   857   0.0  
ref|ZP_02882853.1|  acetolactate synthase, large subunit, bi...   857   0.0  
ref|ZP_01793476.1|  acetolactate synthase 3 catalytic subuni...   857   0.0  
ref|YP_273153.1|  acetolactate synthase 3 catalytic subunit ...   857   0.0  
ref|YP_001858247.1|  acetolactate synthase, large subunit, b...   857   0.0  
ref|NP_240056.1|  acetolactate synthase large subunit [Buchn...   857   0.0  
emb|CAJ43227.1|  acetolactate synthase large subunit [Buchne...   857   0.0  
ref|NP_213319.1|  acetolactate synthase large subunit [Aquif...   856   0.0  
ref|YP_002801350.1|  Acetolactate synthase, large subunit, b...   856   0.0  
ref|ZP_02179310.1|  acetolactate synthase large subunit [Hyd...   856   0.0  
ref|NP_660569.1|  acetolactate synthase large subunit [Buchn...   856   0.0  
ref|YP_001186506.1|  acetolactate synthase 3 catalytic subun...   856   0.0  
ref|YP_621531.1|  acetolactate synthase 3 catalytic subunit ...   856   0.0  
ref|ZP_01552517.1|  acetolactate synthase, large subunit [Me...   856   0.0  
ref|YP_233942.1|  acetolactate synthase 3 catalytic subunit ...   855   0.0  
ref|YP_660207.1|  acetolactate synthase, large subunit, bios...   854   0.0  
ref|ZP_01109309.1|  acetolactate synthase III large subunit ...   854   0.0  
ref|YP_001571876.1|  hypothetical protein SARI_02887 [Salmon...   854   0.0  
ref|YP_001586422.1|  hypothetical protein SPAB_00147 [Salmon...   854   0.0  
ref|YP_528016.1|  acetolactate synthase 3 catalytic subunit ...   854   0.0  
ref|ZP_02177150.1|  acetolactate synthase large subunit [Hyd...   853   0.0  
ref|NP_952960.1|  acetolactate synthase, large subunit, bios...   853   0.0  
ref|YP_001565881.1|  acetolactate synthase, large subunit, b...   853   0.0  
ref|YP_263824.1|  acetolactate synthase 3 catalytic subunit ...   853   0.0  
ref|YP_401831.1|  acetolactate synthase 3 catalytic subunit ...   852   0.0  
ref|ZP_00980135.1|  COG0028: Thiamine pyrophosphate-requirin...   852   0.0  
ref|YP_579789.1|  acetolactate synthase 3 catalytic subunit ...   852   0.0  
ref|YP_610156.1|  acetolactate synthase 3 catalytic subunit ...   851   0.0  
ref|YP_047618.1|  acetolactate synthase 3 catalytic subunit ...   851   0.0  
emb|CAJ72436.1|  strongly similar to acetohydroxy acid synth...   851   0.0  
ref|ZP_01895495.1|  acetolactate synthase, large subunit, bi...   851   0.0  
ref|YP_001021296.1|  acetolactate synthase 3 catalytic subun...   851   0.0  
ref|YP_001269848.1|  acetolactate synthase 3 catalytic subun...   851   0.0  
ref|NP_746789.1|  acetolactate synthase 3 catalytic subunit ...   851   0.0  
gb|AAX64019.1|  acetolactate synthase III, valine sensitive,...   850   0.0  
ref|ZP_00965775.1|  COG0028: Thiamine pyrophosphate-requirin...   849   0.0  
ref|YP_864823.1|  acetolactate synthase, large subunit, bios...   849   0.0  
ref|YP_384221.1|  Acetolactate synthase, large subunit, bios...   848   0.0  
ref|ZP_01737642.1|  acetolactate synthase III large subunit ...   848   0.0  
gb|AAF13787.1|AF129501_2  acetohydroxy acid synthase large s...   848   0.0  
ref|YP_754808.1|  acetolactate synthase large subunit [Syntr...   848   0.0  
ref|YP_001670900.1|  acetolactate synthase, large subunit, b...   848   0.0  
gb|AAF13795.1|AF129503_2  acetohydroxy acid synthase large s...   847   0.0  
ref|ZP_03823351.1|  acetolactate synthase III, large subunit...   847   0.0  
ref|ZP_01307827.1|  acetolactate synthase, large subunit, bi...   846   0.0  
ref|YP_001651736.1|  acetolactate synthase large subunit [Ac...   846   0.0  
ref|YP_001747628.1|  acetolactate synthase, large subunit, b...   846   0.0  
ref|YP_262327.1|  acetolactate synthase 3 catalytic subunit ...   844   0.0  
ref|YP_286275.1|  Acetolactate synthase, large subunit, bios...   844   0.0  
ref|YP_341947.1|  acetolactate synthase isozyme III large su...   843   0.0  
ref|YP_001344340.1|  acetolactate synthase, large subunit, b...   843   0.0  
ref|ZP_01868427.1|  acetolactate synthase III large subunit ...   843   0.0  
ref|YP_902220.1|  acetolactate synthase, large subunit, bios...   842   0.0  
gb|ABY60980.1|  acetolactate synthase 3 catalytic subunit [u...   841   0.0  
ref|YP_001053432.1|  acetolactate synthase 3 catalytic subun...   841   0.0  
ref|ZP_01613488.1|  acetolactate synthase isozyme III large ...   839   0.0  
ref|YP_357321.1|  acetolactate synthase, large subunit, bios...   839   0.0  
ref|ZP_01774694.1|  acetolactate synthase, large subunit, bi...   839   0.0  
ref|ZP_01104736.1|  Acetolactate synthase isozyme III large ...   837   0.0  
ref|YP_001173731.1|  acetolactate synthase 3 catalytic subun...   837   0.0  
ref|YP_981951.1|  acetolactate synthase 3 catalytic subunit ...   836   0.0  
ref|YP_010595.1|  acetolactate synthase, large subunit, bios...   836   0.0  
ref|ZP_01188450.1|  Acetolactate synthase, large subunit, bi...   835   0.0  
ref|ZP_01132006.1|  acetolactate synthase isozyme III large ...   835   0.0  
ref|YP_967136.1|  acetolactate synthase, large subunit, bios...   835   0.0  
ref|YP_842552.1|  acetolactate synthase 3 catalytic subunit ...   835   0.0  
ref|ZP_01627667.1|  diguanylate cyclase/phosphodiesterase (G...   834   0.0  
ref|YP_066505.1|  acetolactate synthase isozyme III, large s...   834   0.0  
ref|NP_459121.1|  acetolactate synthase 3 catalytic subunit ...   834   0.0  
ref|ZP_01074485.1|  acetolactate synthase III large subunit ...   833   0.0  
ref|ZP_00135474.1|  COG0028: Thiamine pyrophosphate-requirin...   833   0.0  
ref|NP_420903.1|  acetolactate synthase 3 catalytic subunit ...   833   0.0  
ref|YP_001340183.1|  acetolactate synthase, large subunit, b...   833   0.0  
ref|ZP_03902833.1|  acetolactate synthase, large subunit [De...   832   0.0  
gb|AAA23047.1|  acetolactate synthase [Caulobacter crescentus]    832   0.0  
ref|NP_682086.1|  acetolactate synthase 3 catalytic subunit ...   832   0.0  
ref|YP_903675.1|  acetolactate synthase, large subunit, bios...   831   0.0  
ref|YP_388660.1|  acetolactate synthase, large subunit, bios...   831   0.0  
ref|ZP_03905694.1|  acetolactate synthase, large subunit [De...   831   0.0  
ref|YP_565425.1|  acetolactate synthase 3 catalytic subunit ...   831   0.0  
ref|YP_847091.1|  acetolactate synthase, large subunit, bios...   831   0.0  
gb|EAY58027.1|  Thiamine pyrophosphate-requiring enzyme [Lep...   829   0.0  
ref|ZP_01224505.1|  acetolactate synthase III large subunit ...   829   0.0  
ref|YP_120445.1|  acetolactate synthase 1 catalytic subunit ...   829   0.0  
ref|ZP_02166090.1|  acetolactate synthase III large subunit ...   828   0.0  
ref|YP_269926.1|  acetolactate synthase III, large subunit, ...   828   0.0  
ref|YP_722490.1|  acetolactate synthase 3 catalytic subunit ...   826   0.0  
ref|YP_001413730.1|  acetolactate synthase, large subunit, b...   826   0.0  
ref|ZP_02118763.1|  acetolactate synthase, large subunit, bi...   826   0.0  
ref|YP_001219254.1|  acetolactate synthase large subunit [Ca...   826   0.0  
ref|YP_886714.1|  acetolactate synthase 1 catalytic subunit ...   826   0.0  
ref|YP_315749.1|  acetolactate synthase, large subunit [Thio...   825   0.0  
ref|YP_706419.1|  acetolactate synthase 1 catalytic subunit ...   825   0.0  
emb|CAA25755.1|  unnamed protein product [Escherichia coli]       825   0.0  
ref|NP_618663.1|  acetolactate synthase 3 catalytic subunit ...   825   0.0  
ref|NP_961972.1|  acetolactate synthase 1 catalytic subunit ...   824   0.0  
ref|YP_001416393.1|  acetolactate synthase, large subunit, b...   824   0.0  
gb|ABL97373.1|  acetolactate synthase III large subunit [unc...   824   0.0  
ref|YP_399158.1|  acetolactate synthase 3 catalytic subunit ...   824   0.0  
ref|YP_172076.1|  acetolactate synthase 3 catalytic subunit ...   824   0.0  
ref|YP_001108257.1|  acetolactate synthase 1 catalytic subun...   823   0.0  
ref|YP_001757953.1|  acetolactate synthase, large subunit, b...   823   0.0  
ref|NP_856673.1|  acetolactate synthase 1 catalytic subunit ...   823   0.0  
ref|NP_632694.1|  acetolactate synthase 3 catalytic subunit ...   823   0.0  
ref|ZP_02971818.1|  acetolactate synthase, large subunit, bi...   822   0.0  
ref|YP_001525292.1|  acetolactate synthase large subunit [Az...   822   0.0  
ref|YP_001111655.1|  acetolactate synthase, large subunit, b...   822   0.0  
emb|CAA38854.1|  acetohydroxy acid synthase AHAS III (IlvI) ...   822   0.0  
ref|NP_337598.1|  acetolactate synthase 1 catalytic subunit ...   821   0.0  
ref|YP_303782.1|  acetolactate synthase 3 catalytic subunit ...   821   0.0  
ref|YP_002765844.1|  acetolactate synthase large subunit [Rh...   821   0.0  
ref|YP_001704053.1|  Acetolactate synthase, large subunit (I...   821   0.0  
ref|YP_002783731.1|  acetolactate synthase large subunit [Rh...   821   0.0  
ref|YP_001327676.1|  acetolactate synthase 3 catalytic subun...   820   0.0  
Sequences not found previously or not previously below threshold:

ref|YP_001797629.1|  acetolactate synthase, large subunit, b...   851   0.0  
ref|NP_386220.1|  acetolactate synthase 3 catalytic subunit ...   820   0.0  
>ref|YP_344503.1| Acetolactate synthase, large subunit, biosynthetic type
           [Nitrosococcus oceani ATCC 19707]
 gb|ABA58973.1| acetolactate synthase, large subunit [Nitrosococcus oceani ATCC
           19707]
          Length = 582

 Score =  899 bits (2324), Expect = 0.0,   Method: Composition-based stats.
 Identities = 115/558 (20%), Positives = 229/558 (41%), Gaps = 23/558 (4%)

Query: 3   TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANG-IKFIPCRNEQAASYAASAYGY 61
            +  +   + LQ  G++ +FG  G  ++ + D +     +K I  R+EQ A++ A  Y  
Sbjct: 4   LSGAEILVRCLQDEGVEYIFGYPGGAVLHIYDALYQQEAVKHILVRHEQGAAHGADGYAR 63

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
            + KPGV+L+  GPG  +A+ GI  +  +  P++VI G   ++ I    FQE+D V +  
Sbjct: 64  ATGKPGVVLVTSGPGATNAVTGIATAYMDSIPMVVITGQVPRAAIGSDAFQEVDSVGITR 123

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
           P +K    +   +++ +  +KA      G  G   +D+P D  +    +  +      L 
Sbjct: 124 PCVKHNFLVKDLNDLALTVRKAFYIATTGRPGPVVVDIPKDVTDPNVKIPYHYPEQLTL- 182

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
                 +    P +IKK V LIL  +   I    G      +  +   V     P   T 
Sbjct: 183 RSYHHPVTVETPEQIKKAVDLILSARRPMIYAGGGVVLGNAAQPLTEFVRLLGYPVTNTL 242

Query: 241 MAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESIF 293
           M  G  P + P       ++ +   +  +   D+++ +GAR +  +  G   ++   +  
Sbjct: 243 MGLGGYPGTDPQFVGMLGMHGTYEANMGMHECDVLIAIGARFDDRVT-GNLEQFCPYAKI 301

Query: 294 IQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQL 353
           I  D +P ++  N      D+ I GD+GL +  ++  L   D       + +    +I+ 
Sbjct: 302 IHVDIDPSSISKN---VQVDIPIVGDVGLVLKEMITVLKSTDKRPDGEALDKWW-SQIEE 357

Query: 354 NQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRL 413
            + R   + +  G  +    +   L  +      +    G + M  A+  +  D PRR +
Sbjct: 358 WRGRRCLRYQQDGKLIKPQYIIERLYEITKGEAYVTSDVGQHQMWTAQF-YKFDKPRRWI 416

Query: 414 DAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNN 473
           ++G   TMG GL  A+  + ++ +  VV + G+++      E+ T ++  L + IV +NN
Sbjct: 417 NSGGLGTMGFGLPAAMGVQLAYLDAPVVCVTGEASIQMCIQELSTCMQYALPIKIVNLNN 476

Query: 474 S--GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLS 529
              G+    ++         + +     +  + +  G     +    ++    ++A  L 
Sbjct: 477 RYMGMVRQWQEFFYDRRYSHSYMDALPDFVKLAEAYGHVGMQIEEPGDVDAALKEAFAL- 535

Query: 530 RTKRETSVINVIIEPGEQ 547
             K     ++ I +  E 
Sbjct: 536 --KDRLVFLDFITDQTEN 551
>ref|YP_114688.1| acetolactate synthase, large subunit, biosynthetic type
           [Methylococcus capsulatus str. Bath]
 gb|AAU91720.1| acetolactate synthase, large subunit, biosynthetic type
           [Methylococcus capsulatus str. Bath]
          Length = 576

 Score =  895 bits (2314), Expect = 0.0,   Method: Composition-based stats.
 Identities = 121/560 (21%), Positives = 233/560 (41%), Gaps = 24/560 (4%)

Query: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAY 59
           M  +  +   Q L+  G++ +FG  G  ++ + D +   + +K I  R+EQ A++AA  Y
Sbjct: 1   MELSGAEIVVQCLKDEGVEYIFGYPGGAVLHIYDALFKQDDVKHILVRHEQGATHAADGY 60

Query: 60  GYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSL 119
              + KPGV+L+  GPG  +A+ GI  +  +  PL+VI G      I    FQE D V +
Sbjct: 61  ARSTGKPGVVLVTSGPGATNAVTGIATAYMDSIPLVVITGQVPLPVIGSDAFQEADIVGI 120

Query: 120 LSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNE 178
             P +K    +     +    +KA      G  G   ID+P D  +     +        
Sbjct: 121 TRPCVKHNFLVKDIHKLAETFKKAFYIATTGRPGPVVIDIPKDVTDPNV--KIPYEYPRS 178

Query: 179 LPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLP 238
           + +          P +IKK V+L+L  +   I    G      + E+  L    + P   
Sbjct: 179 VSLRSYNPSVKGHPIQIKKAVELMLSARRPMIYSGGGVILGNAADELTTLTRLLDFPITN 238

Query: 239 TPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSES 291
           T M  G  P +         ++ +   + A+   D++L +GAR +  +  G   ++   +
Sbjct: 239 TLMGLGGYPATDRQFVGMLGMHGTYEANMAMHDCDVLLAVGARFDDRVT-GKIAEFCPGA 297

Query: 292 IFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKI 351
             I  D +P ++     +   D+ I GD+   +  ++E +           +K     +I
Sbjct: 298 KIIHIDVDPASISK---TVKVDIPIVGDVAPVLADMIELIKTSGRTPDAEALKAWW-ARI 353

Query: 352 QLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRR 411
              ++    +      ++    V   L  L      +    G + M  A+  +  D PRR
Sbjct: 354 DQWRSLDCLRYDRSSDRIKPQFVIEQLWELTRGDAFVASDVGQHQMWAAQ-YYKFDKPRR 412

Query: 412 RLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVM 471
            +++G   TMG GL  A+  K +HP+ +V+ I G+++      E+ TA++ +  + IV +
Sbjct: 413 WVNSGGLGTMGFGLPAAIGIKLAHPQEEVICITGEASIQMCIQELATALQYRTPVKIVNL 472

Query: 472 NNS--GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           NN   G+    ++         + L     +  + +  G     ++  +++    ++A++
Sbjct: 473 NNGYMGMVRQWQEFIYESRYSHSYLETLPDFVKLAEAYGHVGMRIDRPADVRPALEEALK 532

Query: 528 LSRTKRETSVINVIIEPGEQ 547
           L   K  T  ++ + +P E 
Sbjct: 533 L---KDRTVFMDFLTDPTEN 549
>ref|ZP_00831646.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Yersinia frederiksenii ATCC 33641]
          Length = 600

 Score =  895 bits (2313), Expect = 0.0,   Method: Composition-based stats.
 Identities = 123/577 (21%), Positives = 238/577 (41%), Gaps = 25/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 26  MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 85

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 86  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGYDAFQECDMVG 145

Query: 119 LLSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   ID+P D +     +       +
Sbjct: 146 ISRPVVKHSFLVKRTEDIPSVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKM--PYAYPD 203

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
           ++ +            +IK+ +Q IL  K   + +  G        E+  L    NLP  
Sbjct: 204 QVSLRSYNPTVQGHRGQIKRALQTILAAKKPIMYVGGGAINSACHAELLTLAEQLNLPVT 263

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   + A+   D++  +G R +         K+  +
Sbjct: 264 SSLMGLGAFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYCPD 322

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +T +++ L++ D    +  ++    + 
Sbjct: 323 ATVLHIDIDPTSISK---TVTADIPIVGDAKQVLTQMLDLLSQIDCVQDFDSLRDWW-QS 378

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R          ++    V  TL  L      +    G + M  A + +P D PR
Sbjct: 379 IEQWRARDCLSYSKDSGKIKPQAVIETLHRLTKGDAYVTSDVGQHQM-FAALYYPFDKPR 437

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  L ++++ 
Sbjct: 438 RWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYNLPVLVLN 497

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     + T  EL     +A+
Sbjct: 498 LNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVSIRTPDELESKLAEAL 557

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
                      ++V ++  E     QI     ++  L
Sbjct: 558 TQLSETNRLVFVDVTVDETEHVYPMQIRGGGMDEMWL 594
>ref|ZP_00822285.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Yersinia bercovieri ATCC 43970]
          Length = 591

 Score =  893 bits (2309), Expect = 0.0,   Method: Composition-based stats.
 Identities = 122/577 (21%), Positives = 233/577 (40%), Gaps = 25/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 17  MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 76

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 77  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGYDAFQECDMVG 136

Query: 119 LLSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   ID+P D +     +        
Sbjct: 137 ISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKM--PYAYPE 194

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
           ++ +            +IK+ +Q IL  K   + +  G        E+       NLP  
Sbjct: 195 QVSLRSYNPTVQGHRGQIKRALQTILAAKRPIMYVGGGAINSACHEELLAFAEKLNLPVT 254

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   + A+   D++  +G R +         K+  +
Sbjct: 255 SSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAIGVRFDDR-TTNNLAKYCPD 313

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +  ++E L + DS   +  ++    + 
Sbjct: 314 ASVVHIDIDPTSISK---TVNADIPIVGDAKQVLVQMLELLPQIDSAQDFDSLRDWW-QS 369

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R          ++    V  TL  L      +    G + M  A + +P D PR
Sbjct: 370 IEQWRARNCLGYNKESGKIKPQAVIETLHRLTKGDAYVTSDVGQHQM-FAALYYPFDKPR 428

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
             +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  L ++++ 
Sbjct: 429 HWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYNLPVLVLN 488

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     + T  EL      A+
Sbjct: 489 LNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGIAIRTPDELESKLADAL 548

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
                      ++V ++  E     QI     ++  L
Sbjct: 549 SQLSETNRLVFVDVTVDETEHVYPMQIRGGGMDEMWL 585
>ref|ZP_00825910.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Yersinia mollaretii ATCC 43969]
          Length = 585

 Score =  892 bits (2307), Expect = 0.0,   Method: Composition-based stats.
 Identities = 120/577 (20%), Positives = 232/577 (40%), Gaps = 25/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 11  MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 70

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 71  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGYDAFQECDMVG 130

Query: 119 LLSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   ID+P D +     +        
Sbjct: 131 ISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKM--PYAYPE 188

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
           ++ +            +IK+ +Q IL  K   + +  G        E+       NLP  
Sbjct: 189 QVSLRSYNPTVQGHRGQIKRALQTILAAKRPIMYVGGGAINSACHEELLAFAEKLNLPVT 248

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   + A+   D++  +G R +         K+  +
Sbjct: 249 SSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYCPD 307

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +  +++ L + D    +  ++    + 
Sbjct: 308 ATVVHIDIDPTSISK---TVNADIPIVGDAKQVLVQMLDLLPQIDCAQDFDSLRDWW-QS 363

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R          ++    V  TL  L      +    G + M  A + +P D PR
Sbjct: 364 IEQWRARNCLGYNKESGKIKPQAVIETLHRLTKGDAYVTSDVGQHQM-FAALYYPFDKPR 422

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
             +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  L ++++ 
Sbjct: 423 HWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYNLPVLVLN 482

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     + T  EL      A+
Sbjct: 483 LNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGIAIRTPEELESKLADAL 542

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
                      ++V ++  E     QI     ++  L
Sbjct: 543 SQLSETNRLVFVDVTVDETEHVYPMQIRGGGMDEMWL 579
>ref|ZP_02462916.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           thailandensis MSMB43]
          Length = 587

 Score =  892 bits (2306), Expect = 0.0,   Method: Composition-based stats.
 Identities = 119/573 (20%), Positives = 228/573 (39%), Gaps = 30/573 (5%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGYIS 63
                 + L    ++ ++G  G  ++ + D +   + I+ +  R+EQAA +AA  Y   +
Sbjct: 23  GATVLMKALADENVEFIWGYPGGSVLYIYDELYKQDKIQHVLVRHEQAAVHAADGYSRST 82

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            K GV L+  GPG+ +A+ GI  +  +  PL+VI+G    + I +  FQE D V +  P 
Sbjct: 83  GKVGVCLVTSGPGVTNAVTGIATAYMDSIPLVVISGQVPTAAIGQDAFQECDTVGITRPC 142

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
           +K    +     +    +KA      G  G   ID+P D  +     E        + + 
Sbjct: 143 VKHNFLVKDVRELAETVKKAFYIARTGRPGPVLIDIPKDISKTPCEYE----PVKSVSLR 198

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMA 242
               +      +I+K V  +L  K   I    G      + E+ +  +    P   T M 
Sbjct: 199 SYNPVTKGHSGQIRKAVSSLLSAKRPYIYTGGGIILADAARELNQFADLLGYPVTNTLMG 258

Query: 243 KGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SIFI 294
            G    S         ++ +   + A++  D+++ +GAR +  +  G    + S     I
Sbjct: 259 LGGYRASDKKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRV-IGDPGHFASRPRKII 317

Query: 295 QFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLN 354
             D +P ++         D+ I GD+   +  L+E+L   +       + Q  ++ I+  
Sbjct: 318 HIDIDPSSISKR---VKVDIPIVGDVKEVLKELIEQLQTAEHGPDTEALAQWWKD-IESW 373

Query: 355 QTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLD 414
           + +   K   +   +    V   L  L D    +    G + M  A+  +  + PRR ++
Sbjct: 374 REKDCLKYDRKSEIIKPQYVVEKLWELTDGNAFVCSDVGQHQMWAAQF-YRFNKPRRWIN 432

Query: 415 AGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS 474
           +G   TMG GL  A+  K +HP+ +VV I G+ +      E+ T  +    + I+ +NN 
Sbjct: 433 SGGLGTMGFGLPAAMGVKMAHPDDEVVCITGEGSIQMCIQELSTCKQYDTPVKIISLNNR 492

Query: 475 --GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSR 530
             G+    + IE       + +     +  + +  G     +   +++    ++A+   R
Sbjct: 493 YLGMVRQWQQIEYSKRYSHSYMDALPDFVKLAQAYGHVGMRIEKSADVEPALKEAL---R 549

Query: 531 TKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
            K  T  ++   +P E       A     +  L
Sbjct: 550 LKDRTVFLDFQTDPTENVWPMVQAGKGITEMLL 582
>ref|ZP_00833010.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Yersinia intermedia ATCC 29909]
          Length = 585

 Score =  891 bits (2305), Expect = 0.0,   Method: Composition-based stats.
 Identities = 123/577 (21%), Positives = 235/577 (40%), Gaps = 25/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 11  MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 70

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 71  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGYDAFQECDMVG 130

Query: 119 LLSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   ID+P D +     +       +
Sbjct: 131 ISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKM--PYAYPD 188

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
           ++ +            +IK+ +Q IL  K   + +  G        E+  L    NLP  
Sbjct: 189 QVSLRSYNPTVQGHRGQIKRALQTILAAKKPIMYVGGGAINSACHEELLVLAEKLNLPVT 248

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   + A+   D++  +G R +         K+   
Sbjct: 249 SSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYCPN 307

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +  ++E L++ D       ++    + 
Sbjct: 308 ATVVHIDIDPTSISK---TVNADIPIVGDAKQVLVQMLELLSQIDCTQDCDSLRDWW-QS 363

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R          ++    V  TL  L      +    G + M  A + +P D PR
Sbjct: 364 IEQWRARNCLSYNKDSGKIKPQAVIETLHRLTSGDAYVTSDVGQHQM-FAALYYPFDKPR 422

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  L ++++ 
Sbjct: 423 RWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYNLPVLVLN 482

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     + T  EL      A+
Sbjct: 483 LNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVSIRTPDELESKLADAL 542

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
                 +    ++V ++  E     QI     ++  L
Sbjct: 543 TQLSETKRLVFVDVTVDETEHVYPMQIRGGGMDEMWL 579
>ref|YP_295170.1| acetolactate synthase 3 catalytic subunit [Ralstonia eutropha
           JMP134]
 gb|AAZ60326.1| acetolactate synthase, large subunit [Ralstonia eutropha JMP134]
          Length = 587

 Score =  891 bits (2304), Expect = 0.0,   Method: Composition-based stats.
 Identities = 123/560 (21%), Positives = 229/560 (40%), Gaps = 27/560 (4%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYG 60
                +     L + G++ V+G  G  ++ + D +      + I  R+EQAA +AA  Y 
Sbjct: 20  EMIGAEILVHALAEEGVEYVWGYPGGAVLYIYDELHKQKKFEHILVRHEQAAVHAADGYA 79

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
             + K GV L+  GPG+ +A+ GI  +  +  P++VI G+     I +  FQE D V + 
Sbjct: 80  RATGKVGVALVTSGPGVTNAVTGIATAYLDSIPMVVITGNVPTHAIGQDAFQECDTVGIT 139

Query: 121 SPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNEL 179
            P +K    +    ++    +KA      G  G   +D+P D        E        L
Sbjct: 140 RPIVKHNFLVKDVRDLASTIKKAFYIASTGRPGPVVVDIPKDVSRNTCKYEY----PKSL 195

Query: 180 PMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPT 239
            M     +      +I+K V L+   +   I    G      S E+R+L      P   T
Sbjct: 196 DMRSYNPVNKGHSGQIRKAVALLQGAERPYIYAGGGVVLANASEELRQLAALTGHPVTNT 255

Query: 240 PMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSES- 291
            M  G  P +S        ++ +   + A++  D+++ +GAR +  +  G    + S++ 
Sbjct: 256 LMGLGSFPGTSKQFVGMLGMHGTYEANMAMQNCDVLIAIGARFDDRV-IGNPSHFTSQAR 314

Query: 292 IFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKI 351
             +  D +P ++         D+ I G++   +  L+ +L   D   K   + +   E+I
Sbjct: 315 KIVHIDIDPSSISKR---VKVDIPIVGNVKDVLQELIAQLQASDVKPKREALAKWW-EQI 370

Query: 352 QLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRR 411
           +  ++    K       +    V   +  L      I    G + M  A+  +  + PRR
Sbjct: 371 EQWRSVDCLKYDRSSEIIKPQYVVEKIWELTKGDAFICSDVGQHQMWAAQF-YKFNEPRR 429

Query: 412 RLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVM 471
            +++G   TMG+GL YA+  K + PE +VV I G+ +      E+ T ++    + I  +
Sbjct: 430 WINSGGLGTMGVGLPYAMGIKKAFPEKEVVTITGEGSIQMCIQELSTCLQFDTPVKICSL 489

Query: 472 NNS--GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           NN   G+    ++IE       + ++    +  + +  G     V   S++    ++A  
Sbjct: 490 NNGYLGMVRQWQEIEYDNRYSHSYMNALPDFVKLAEAYGHVGMRVEKTSDVEPALREAF- 548

Query: 528 LSRTKRETSVINVIIEPGEQ 547
             R K  T  ++   +P E 
Sbjct: 549 --RLKDRTVFLDFQTDPTEN 566
>ref|YP_001476982.1| acetolactate synthase, large subunit, biosynthetic type [Serratia
           proteamaculans 568]
 gb|ABV39854.1| acetolactate synthase, large subunit, biosynthetic type [Serratia
           proteamaculans 568]
          Length = 572

 Score =  891 bits (2303), Expect = 0.0,   Method: Composition-based stats.
 Identities = 128/581 (22%), Positives = 235/581 (40%), Gaps = 33/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  I  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHILVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGEVGVVLVTSGPGATNAITGIATAYMDSIPMVVLSGQVPSSLIGYDAFQECDMVG 120

Query: 119 LLSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  I +KA      G  G   ID+P D +     +        
Sbjct: 121 ISRPVVKHSFLVKRTEDIPGILKKAFYLASTGRPGPVVIDLPKDIVGPAVRM--PYAYPQ 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
           ++ M            +IK+ +  IL  K   + +  G        E+  L    NLP  
Sbjct: 179 DVSMRSYNPTVQGHRGQIKRALHTILTAKKPVMYVGGGAINSACDAELLELAEKLNLPVT 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            T M  G  P +         ++ +   ++ +  +D++  +G R +         K+   
Sbjct: 239 CTLMGLGAFPGTHRQSVGMLGMHGTYEANKTMHNSDVIFAVGVRFDDR-TTNNLAKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +T ++E L ++D    +  ++   +  
Sbjct: 298 ATVLHIDIDPTSISK---TVDADIPIVGDAKQVLTQMLELLAQEDKAQDHDALRDWWQA- 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R           +    V  TL  L      +    G + M  A + +P D PR
Sbjct: 354 IEQWRARDCLGYDKNSGTIKPQAVIETLHRLTRGDAYVTSDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  L +++V 
Sbjct: 413 RWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYNLPVIVVN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     + T  EL     QA+
Sbjct: 473 LNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHVGIAIRTPDELESKLAQAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
                K     ++V ++  E           +   W +K  
Sbjct: 533 A---EKERLVFVDVTVDETEHVYPMQIRGGSMDEMWLSKTE 570
>ref|ZP_02355077.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           oklahomensis EO147]
          Length = 587

 Score =  890 bits (2301), Expect = 0.0,   Method: Composition-based stats.
 Identities = 121/573 (21%), Positives = 228/573 (39%), Gaps = 30/573 (5%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGYIS 63
                 + L    ++ ++G  G  ++ + D +   + I+ +  R+EQAA +AA AY   +
Sbjct: 23  GATVLMKALADENVEFIWGYPGGSVLYIYDELYKQDKIQHVLVRHEQAAVHAADAYSRST 82

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            K GV L+  GPG+ +A+ GI  +  +  PL+VI+G    + I +  FQE D V +  P 
Sbjct: 83  GKVGVCLVTSGPGVTNAVTGIATAYMDSIPLVVISGQVPTAAIGQDAFQECDTVGITRPC 142

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
           +K    +     +    +KA      G  G   ID+P D  +     E        + + 
Sbjct: 143 VKHNFLVKDVRELAETVKKAFYIARTGRPGPVLIDIPKDISKTPCEYE----PVKNVSLR 198

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMA 242
               +      +I+K V L+L  K   I    G      S E+ +  +    P   T M 
Sbjct: 199 SYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGIILADASRELNQFADLLGYPVTNTLMG 258

Query: 243 KGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SIFI 294
            G    S         ++ +   + A++  D+++ +GAR +  +  G    + S     I
Sbjct: 259 LGGYRASDKKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRV-IGDPGHFASRPRKII 317

Query: 295 QFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLN 354
             D +P ++         D+ I GD+   +  L+E+L   +       + Q  ++ I+  
Sbjct: 318 HIDIDPSSISKR---VKVDIPIVGDVKEVLKDLIEQLQTAEHGPDTEALAQWWKD-IESW 373

Query: 355 QTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLD 414
           + +   K       +    V      L D    +    G + M  A+  +  + PRR ++
Sbjct: 374 RAKDCLKYDRESEIIKPQYVVEKAWELTDGNAFVCSDVGQHQMWAAQF-YRFNKPRRWIN 432

Query: 415 AGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS 474
           +G   TMG GL  A+  K +HP+ DV+ I G+ +      E+ T  +    + I+ +NN 
Sbjct: 433 SGGLGTMGFGLPAAMGVKMAHPDDDVLCITGEGSIQMCIQELSTCKQYDTPVKIISLNNR 492

Query: 475 --GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSR 530
             G+    + IE       + +     +  + +  G     +   +++    ++A+   R
Sbjct: 493 YLGMVRQWQQIEYSKRYSHSYMDALPDFVKLAEAYGHVGMRIEKSADVEPALKEAL---R 549

Query: 531 TKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
            K  T  ++   +P E       A     +  L
Sbjct: 550 LKDRTVFLDFQTDPTENVWPMVQAGKGITEMLL 582
>ref|YP_001005008.1| acetolactate synthase 3 catalytic subunit [Yersinia enterocolitica
           subsp. enterocolitica 8081]
 emb|CAL10768.1| acetolactate synthase isozyme III large subunit [Yersinia
           enterocolitica subsp. enterocolitica 8081]
          Length = 575

 Score =  889 bits (2300), Expect = 0.0,   Method: Composition-based stats.
 Identities = 122/577 (21%), Positives = 233/577 (40%), Gaps = 25/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGFDAFQECDMVG 120

Query: 119 LLSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   ID+P D +     +        
Sbjct: 121 ISRPVVKHSFLVKRTEDIPTVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKM--PYAYPE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
           ++ +            +IK+ +Q IL  K   + +  G        E+  L    NLP  
Sbjct: 179 QVSLRSYNPTVQGHRGQIKRALQTILAAKRPIMYVGGGAINSACHEELLTLAEKLNLPVT 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   + A+   D++  +G R +         K+   
Sbjct: 239 SSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +T +++ L + D    +  ++    + 
Sbjct: 298 AAVVHIDIDPTSISK---TVEADIPIVGDAKQVLTQMLDLLPQIDCAQDFDSLRDWW-QS 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R          ++    V  TL  L      +    G + M  A + +P D PR
Sbjct: 354 IEQWRARDCLSYAKDSGKIKPQAVIETLHRLTKGDAYVTSDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
             +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  L ++++ 
Sbjct: 413 HWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYNLPVLVLN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     + T  EL      A+
Sbjct: 473 LNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVSIRTPDELESKLADAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
                      ++V ++  E     QI     ++  L
Sbjct: 533 TQLSETNRLVFVDVTVDETEHVYPMQIRGGGMDEMWL 569
>ref|YP_583066.1| acetolactate synthase 3 catalytic subunit [Ralstonia metallidurans
           CH34]
 gb|ABF07797.1| acetolactate synthase, large subunit [Ralstonia metallidurans CH34]
          Length = 587

 Score =  889 bits (2299), Expect = 0.0,   Method: Composition-based stats.
 Identities = 119/560 (21%), Positives = 227/560 (40%), Gaps = 27/560 (4%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVAN-GIKFIPCRNEQAASYAASAYG 60
                +     L + G++ V+G  G  ++ + D +      + I  R+EQAA +AA  Y 
Sbjct: 20  EMIGAEILVNALAEEGVEYVWGYPGGAVLYIYDELHKQTKFEHILVRHEQAAVHAADGYA 79

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
             + K GV L+  GPG+ +A+ GI  +  +  P++VI G+     I +  FQE D V + 
Sbjct: 80  RATGKVGVALVTSGPGVTNAVTGIATAYLDSIPMVVITGNVPTHAIGQDAFQECDTVGIT 139

Query: 121 SPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNEL 179
            P +K    +    ++    +KA      G  G   +D+P D        E        +
Sbjct: 140 RPIVKHNFLVKDVRDLAATIKKAFFIAATGRPGPVVVDIPKDVSRNSCKYEY----PKSI 195

Query: 180 PMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPT 239
            M     +      +I+K V L+   +   I    G      S E+R L      P   T
Sbjct: 196 DMRSYSPVNKGHSGQIRKAVALLQSAERPYIYSGGGVVLANASEELRELAALTGHPVTNT 255

Query: 240 PMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSES- 291
            M  G  P +S        ++ +   + A++  D+++ +GAR +  +  G    + +++ 
Sbjct: 256 LMGLGAFPGTSKQFVGMLGMHGTYEANMAMQNCDVLIAIGARFDDRV-IGNPSHFTAQAR 314

Query: 292 IFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKI 351
             I  D +P ++         D+ I G++   +  L+ ++   D   K   + +   E+I
Sbjct: 315 KIIHIDIDPSSISKR---VKVDIPIVGNVKDVLQELISQIKTSDIKPKREALAKWW-EQI 370

Query: 352 QLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRR 411
           +  ++    K       +    V   +  L      I    G + M  A+  +  + PRR
Sbjct: 371 EKWRSVDCLKYDRSSEIIKPQYVVEKIWELTHGDAFICSDVGQHQMWAAQF-YKFNEPRR 429

Query: 412 RLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVM 471
            +++G   TMG+GL YA+  K + P+ +VV I G+ +      E+ T ++    + I  +
Sbjct: 430 WINSGGLGTMGVGLPYAMGIKKAFPDKEVVTITGEGSIQMCIQELSTCLQYDTPVKICSL 489

Query: 472 NNS--GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           NN   G+    ++IE       + +     +  + +  G     +   S++    ++A  
Sbjct: 490 NNGYLGMVRQWQEIEYDNRYSHSYMQALPDFVKLAEAYGHVGMRIEKSSDVEPALREAF- 548

Query: 528 LSRTKRETSVINVIIEPGEQ 547
             R K  T  ++   +P E 
Sbjct: 549 --RLKDRTVFLDFQTDPTEN 566
>ref|ZP_02362280.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           oklahomensis C6786]
          Length = 587

 Score =  889 bits (2298), Expect = 0.0,   Method: Composition-based stats.
 Identities = 121/573 (21%), Positives = 229/573 (39%), Gaps = 30/573 (5%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGYIS 63
                 + L    ++ ++G  G  ++ + D +   + I+ +  R+EQAA +AA AY   +
Sbjct: 23  GATVLMKALADENVEFIWGYPGGSVLYIYDELYKQDKIQHVLVRHEQAAVHAADAYSRST 82

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            K GV L+  GPG+ +A+ GI  +  +  PL+VI+G    + I +  FQE D V +  P 
Sbjct: 83  GKVGVCLVTSGPGVTNAVTGIATAYMDSIPLVVISGQVPTAAIGQDAFQECDTVGITRPC 142

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
           +K    +     +    +KA      G  G   ID+P D  +     E        + + 
Sbjct: 143 VKHNFLVKDVRELAETVKKAFYIARTGRPGPVLIDIPKDISKTPCEYE----PVKNVSLR 198

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMA 242
               +      +I+K V L+L  K   I    G      S E+ +  +    P   T M 
Sbjct: 199 SYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGIILADASRELNQFADLLGYPVTNTLMG 258

Query: 243 KGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SIFI 294
            G    S         ++ +   + A++  D+++ +GAR +  +  G    + S     I
Sbjct: 259 LGGYRASDKKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRV-IGDPGHFASRPRKII 317

Query: 295 QFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLN 354
             D +P ++         D+ I GD+   +  L+E+L   +       + Q  ++ I+  
Sbjct: 318 HIDIDPSSISKR---VKVDIPIVGDVKEVLKDLIEQLQTAEHGPDTEALAQWWKD-IESW 373

Query: 355 QTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLD 414
           + +   K       +    V      L D    +    G + M +A+  +  + PRR ++
Sbjct: 374 RAKDCLKYDRESEIIKPQYVVEKAWELTDGNAFVCSDVGQHQMWVAQF-YRFNKPRRWIN 432

Query: 415 AGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS 474
           +G   TMG GL  A+  K +HP+ DV+ I G+ +      E+ T  +    + I+ +NN 
Sbjct: 433 SGGLGTMGFGLPAAMGVKMAHPDDDVLCITGEGSIQMCIQELSTCKQYDTPVKIISLNNR 492

Query: 475 --GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSR 530
             G+    + IE       + +     +  + +  G     +   +++    ++A+   R
Sbjct: 493 YLGMVRQWQQIEYSKRYSHSYMDALPDFVKLAEAYGHVGMRIEKSADVEPALKEAL---R 549

Query: 531 TKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
            K  T  ++   +P E       A     +  L
Sbjct: 550 LKDRTVFLDFQTDPTENVWPMVQAGKGITEMLL 582
>ref|YP_107818.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei K96243]
 ref|YP_332829.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei 1710b]
 ref|YP_001058323.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei 668]
 ref|YP_001065560.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei 1106a]
 ref|ZP_02103326.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei 1106b]
 ref|ZP_02114257.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei 1710a]
 ref|ZP_02402063.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei DM98]
 ref|ZP_02410608.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei 14]
 ref|ZP_02446699.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei 91]
 ref|ZP_02454907.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei 9]
 ref|ZP_02470493.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei B7210]
 ref|ZP_02480930.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei 7894]
 ref|ZP_02489181.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei NCTC 13177]
 ref|ZP_02497301.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei 112]
 ref|ZP_02505333.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           pseudomallei BCC215]
 emb|CAH35191.1| acetolactate synthase isozyme III large subunit [Burkholderia
           pseudomallei K96243]
 gb|ABA49202.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia pseudomallei 1710b]
 gb|ABN84943.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia pseudomallei 668]
 gb|ABN89379.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia pseudomallei 1106a]
 gb|EDO85430.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia pseudomallei 406e]
 gb|EDO93911.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia pseudomallei Pasteur 52237]
 gb|EDS84541.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia pseudomallei S13]
 gb|EDU08784.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia pseudomallei 1655]
          Length = 587

 Score =  886 bits (2292), Expect = 0.0,   Method: Composition-based stats.
 Identities = 124/573 (21%), Positives = 228/573 (39%), Gaps = 30/573 (5%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGYIS 63
                 + L    ++ ++G  G  ++ + D +   + I+ +  R+EQAA +AA AY   +
Sbjct: 23  GATVLMKALADENVEFIWGYPGGSVLYIYDELYKQDKIQHVLVRHEQAAVHAADAYSRST 82

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            K GV L+  GPG+ +A+ GI  +  +  PL+VI+G    + I +  FQE D V +  P 
Sbjct: 83  GKVGVCLVTSGPGVTNAVTGIATAYMDSIPLVVISGQVPTAAIGQDAFQECDTVGITRPC 142

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
           +K    +     +    +KA      G  G   ID+P D  +     E        + + 
Sbjct: 143 VKHNFLVKDVRELAQTVKKAFYIARTGRPGPVLIDIPKDISKTPCEYE----PVKNVSLR 198

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMA 242
               +      +I+K V L+L  K   I    G      S E+ +  +    P   T M 
Sbjct: 199 SYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGIILADASRELNQFADLLGYPVTNTLMG 258

Query: 243 KGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SIFI 294
            G    S         ++ +   + A++  D+++ +GAR +  +  G    + S     I
Sbjct: 259 LGGYRSSDRKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRV-IGDPAHFASRPRKII 317

Query: 295 QFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLN 354
             D +P ++         D+ I GD+   +  L+E+L   +       + Q  +E I+  
Sbjct: 318 HIDIDPSSISKR---VKVDIPIVGDVKEVLKELIEQLQTAEHGPDADALAQWWKE-IEGW 373

Query: 355 QTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLD 414
           +     K       +    V   L  L D    +    G + M  A+  +  + PRR ++
Sbjct: 374 RGTDCLKYDRASEIIKPQYVVEKLWELTDGNAFVCSDVGQHQMWAAQF-YRFNKPRRWIN 432

Query: 415 AGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS 474
           +G   TMG GL  A+  K +HP+ DVV I G+ +      E+ T  +    + I+ +NN 
Sbjct: 433 SGGLGTMGFGLPAAMGVKMAHPDDDVVCITGEGSIQMCIQELSTCKQYDTPVKIISLNNR 492

Query: 475 --GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSR 530
             G+    + IE       + +     +  + +  G     +   +++    ++A+ L  
Sbjct: 493 YLGMVRQWQQIEYSKRYSHSYMDALPDFVKLAQAYGHIGMRIEKSADVEPALKEALSL-- 550

Query: 531 TKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
            K  T  ++   +P E       A     +  L
Sbjct: 551 -KDRTVFLDFQTDPTENVWPMVQAGKGITEMLL 582
>ref|YP_725545.1| acetolactate synthase 3 catalytic subunit [Ralstonia eutropha H16]
 emb|CAJ92177.1| acetolactate synthase III (valine sensitive) [Ralstonia eutropha
           H16]
          Length = 585

 Score =  886 bits (2291), Expect = 0.0,   Method: Composition-based stats.
 Identities = 123/560 (21%), Positives = 228/560 (40%), Gaps = 27/560 (4%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVAN-GIKFIPCRNEQAASYAASAYG 60
                +     L + G++ V+G  G  ++ + D +      + I  R+EQAA +AA  Y 
Sbjct: 18  EMIGAEILVHALAEEGVEYVWGYPGGAVLYIYDELHKQTKFEHILVRHEQAAVHAADGYA 77

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
             + K GV L+  GPG+ +A+ GI  +  +  P++VI G+     I +  FQE D V + 
Sbjct: 78  RATGKVGVALVTSGPGVTNAVTGIATAYLDSIPMVVITGNVPTHAIGQDAFQECDTVGIT 137

Query: 121 SPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNEL 179
            P +K    +    ++    +KA      G  G   +D+P D        E        +
Sbjct: 138 RPIVKHNFLVKDVRDLAATIKKAFFIAATGRPGPVVVDIPKDVSRNACKYEY----PKSI 193

Query: 180 PMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPT 239
            M     +      +I+K V L+   +   I    G      S E+R+L      P   T
Sbjct: 194 DMRSYNPVNKGHSGQIRKAVALLQGAERPYIYTGGGVVLANASDELRQLAALTGHPVTNT 253

Query: 240 PMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSES- 291
            M  G  P +S        ++ +   + A++  D+++ +GAR +  +  G    + S++ 
Sbjct: 254 LMGLGAFPGTSKQFVGMLGMHGTYEANMAMQNCDVLIAIGARFDDRV-IGNPAHFTSQAR 312

Query: 292 IFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKI 351
             I  D +P ++         D+ I G++   +  L+ ++   D   K   + +   E+I
Sbjct: 313 KIIHIDIDPSSISKR---VKVDIPIVGNVKDVLQELIAQIKASDIKPKREALAKWW-EQI 368

Query: 352 QLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRR 411
           +  ++    K       +    V   +  L      I    G + M  A+  +  D PRR
Sbjct: 369 EQWRSVDCLKYDRSSEIIKPQYVVEKIWELTKGDAFICSDVGQHQMWAAQF-YKFDEPRR 427

Query: 412 RLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVM 471
            +++G   TMG+GL YA+  K + PE +VV I G+ +      E+ T ++    + I  +
Sbjct: 428 WINSGGLGTMGVGLPYAMGIKKAFPEKEVVTITGEGSIQMCIQELSTCLQYDTPVKICSL 487

Query: 472 NNS--GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           NN   G+    ++IE       + +     +  + +  G     V   S++    ++A  
Sbjct: 488 NNGYLGMVRQWQEIEYDNRYSHSYMDALPDFVKLAEAYGHVGMRVEKTSDVEPALREAF- 546

Query: 528 LSRTKRETSVINVIIEPGEQ 547
             R K  T  ++   +P E 
Sbjct: 547 --RLKDRTVFLDFQTDPTEN 564
>gb|EDK58417.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia mallei JHU]
 gb|EDK87021.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia mallei 2002721280]
          Length = 585

 Score =  886 bits (2291), Expect = 0.0,   Method: Composition-based stats.
 Identities = 124/573 (21%), Positives = 228/573 (39%), Gaps = 30/573 (5%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGYIS 63
                 + L    ++ ++G  G  ++ + D +   + I+ +  R+EQAA +AA AY   +
Sbjct: 21  GATVLMKALADENVEFIWGYPGGSVLYIYDELYKQDKIQHVLVRHEQAAVHAADAYSRST 80

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            K GV L+  GPG+ +A+ GI  +  +  PL+VI+G    + I +  FQE D V +  P 
Sbjct: 81  GKVGVCLVTSGPGVTNAVTGIATAYMDSIPLVVISGQVPTAAIGQDAFQECDTVGITRPC 140

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
           +K    +     +    +KA      G  G   ID+P D  +     E        + + 
Sbjct: 141 VKHNFLVKDVRELAQTVKKAFYIARTGRPGPVLIDIPKDISKTPCEYE----PVKNVSLR 196

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMA 242
               +      +I+K V L+L  K   I    G      S E+ +  +    P   T M 
Sbjct: 197 SYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGIILADASRELNQFADLLGYPVTNTLMG 256

Query: 243 KGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SIFI 294
            G    S         ++ +   + A++  D+++ +GAR +  +  G    + S     I
Sbjct: 257 LGGYRSSDRKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRV-IGDPAHFASRPRKII 315

Query: 295 QFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLN 354
             D +P ++         D+ I GD+   +  L+E+L   +       + Q  +E I+  
Sbjct: 316 HIDIDPSSISKR---VKVDIPIVGDVKEVLKELIEQLQTAEHGSDADALAQWWKE-IEGW 371

Query: 355 QTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLD 414
           +     K       +    V   L  L D    +    G + M  A+  +  + PRR ++
Sbjct: 372 RGTDCLKYDRASEIIKPQYVVEKLWELTDGNAFVCSDVGQHQMWAAQF-YRFNKPRRWIN 430

Query: 415 AGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS 474
           +G   TMG GL  A+  K +HP+ DVV I G+ +      E+ T  +    + I+ +NN 
Sbjct: 431 SGGLGTMGFGLPAAMGVKMAHPDDDVVCITGEGSIQMCIQELSTCKQYDTPVKIISLNNR 490

Query: 475 --GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSR 530
             G+    + IE       + +     +  + +  G     +   +++    ++A+ L  
Sbjct: 491 YLGMVRQWQQIEYSKRYSHSYMDALPDFVKLAQAYGHIGMRIEKSADVEPALKEALSL-- 548

Query: 531 TKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
            K  T  ++   +P E       A     +  L
Sbjct: 549 -KDRTVFLDFQTDPTENVWPMVQAGKGITEMLL 580
>ref|YP_103451.1| acetolactate synthase 3 catalytic subunit [Burkholderia mallei ATCC
           23344]
 ref|YP_992453.1| acetolactate synthase 3 catalytic subunit [Burkholderia mallei
           SAVP1]
 ref|YP_001026743.1| acetolactate synthase 3 catalytic subunit [Burkholderia mallei NCTC
           10229]
 ref|YP_001079971.1| acetolactate synthase 3 catalytic subunit [Burkholderia mallei NCTC
           10247]
 ref|ZP_02266201.1| acetolactate synthase 3 catalytic subunit [Burkholderia mallei
           PRL-20]
 gb|AAU49869.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia mallei ATCC 23344]
 gb|ABM52731.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia mallei SAVP1]
 gb|ABN01979.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia mallei NCTC 10229]
 gb|ABO06387.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia mallei NCTC 10247]
 gb|EDK53450.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia mallei FMH]
 gb|EDP86451.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia mallei ATCC 10399]
          Length = 587

 Score =  886 bits (2291), Expect = 0.0,   Method: Composition-based stats.
 Identities = 124/573 (21%), Positives = 228/573 (39%), Gaps = 30/573 (5%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGYIS 63
                 + L    ++ ++G  G  ++ + D +   + I+ +  R+EQAA +AA AY   +
Sbjct: 23  GATVLMKALADENVEFIWGYPGGSVLYIYDELYKQDKIQHVLVRHEQAAVHAADAYSRST 82

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            K GV L+  GPG+ +A+ GI  +  +  PL+VI+G    + I +  FQE D V +  P 
Sbjct: 83  GKVGVCLVTSGPGVTNAVTGIATAYMDSIPLVVISGQVPTAAIGQDAFQECDTVGITRPC 142

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
           +K    +     +    +KA      G  G   ID+P D  +     E        + + 
Sbjct: 143 VKHNFLVKDVRELAQTVKKAFYIARTGRPGPVLIDIPKDISKTPCEYE----PVKNVSLR 198

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMA 242
               +      +I+K V L+L  K   I    G      S E+ +  +    P   T M 
Sbjct: 199 SYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGIILADASRELNQFADLLGYPVTNTLMG 258

Query: 243 KGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SIFI 294
            G    S         ++ +   + A++  D+++ +GAR +  +  G    + S     I
Sbjct: 259 LGGYRSSDRKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRV-IGDPAHFASRPRKII 317

Query: 295 QFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLN 354
             D +P ++         D+ I GD+   +  L+E+L   +       + Q  +E I+  
Sbjct: 318 HIDIDPSSISKR---VKVDIPIVGDVKEVLKELIEQLQTAEHGSDADALAQWWKE-IEGW 373

Query: 355 QTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLD 414
           +     K       +    V   L  L D    +    G + M  A+  +  + PRR ++
Sbjct: 374 RGTDCLKYDRASEIIKPQYVVEKLWELTDGNAFVCSDVGQHQMWAAQF-YRFNKPRRWIN 432

Query: 415 AGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS 474
           +G   TMG GL  A+  K +HP+ DVV I G+ +      E+ T  +    + I+ +NN 
Sbjct: 433 SGGLGTMGFGLPAAMGVKMAHPDDDVVCITGEGSIQMCIQELSTCKQYDTPVKIISLNNR 492

Query: 475 --GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSR 530
             G+    + IE       + +     +  + +  G     +   +++    ++A+ L  
Sbjct: 493 YLGMVRQWQQIEYSKRYSHSYMDALPDFVKLAQAYGHIGMRIEKSADVEPALKEALSL-- 550

Query: 531 TKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
            K  T  ++   +P E       A     +  L
Sbjct: 551 -KDRTVFLDFQTDPTENVWPMVQAGKGITEMLL 582
>ref|YP_001607309.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis Angola]
 ref|ZP_02224048.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. F1991016]
 ref|ZP_02226386.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. IP275]
 ref|ZP_02229832.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. E1979001]
 ref|ZP_02237893.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. B42003004]
 ref|ZP_02306711.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. UG05-0454]
 ref|ZP_02313804.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. MG05-1020]
 ref|ZP_02318188.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Mediaevalis str. K1973002]
 gb|AAM87188.1|AE013966_5 acetolactate synthase III, large subunit [Yersinia pestis KIM]
 gb|AAS63794.1| acetolactate synthase isozyme III large subunit [Yersinia pestis
           biovar Microtus str. 91001]
 gb|ABX88215.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis Angola]
 gb|EDR32853.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. IP275]
 gb|EDR37128.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. F1991016]
 gb|EDR44574.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. E1979001]
 gb|EDR51084.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. B42003004]
 gb|EDR56209.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Orientalis str. MG05-1020]
 gb|EDR60644.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Antiqua str. UG05-0454]
 gb|EDR64341.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pestis biovar Mediaevalis str. K1973002]
          Length = 593

 Score =  886 bits (2290), Expect = 0.0,   Method: Composition-based stats.
 Identities = 123/577 (21%), Positives = 236/577 (40%), Gaps = 25/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 19  MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 78

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 79  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGFDAFQECDMVG 138

Query: 119 LLSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I M+ +KA      G  G   ID+P D +     +        
Sbjct: 139 ISRPVVKHSFLVKRTEDIPMVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKM--PYAYPE 196

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
           ++ +            +IK+ +Q I+  K   + +  G        E+  L    NLP  
Sbjct: 197 QVSLRSYNPTVQGHRGQIKRALQTIMAAKRPIMYVGGGAINAACHEELLILAEKLNLPVT 256

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   + A+   D++  +G R +         K+  +
Sbjct: 257 SSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYCPD 315

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +T +++ L++      +  ++    + 
Sbjct: 316 ATVLHIDIDPTSISK---TVTADIPIVGDAKQVLTQMLDLLSQVGCTQDFDSLRDWW-QS 371

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  +TR          ++    V   L  L      +    G + M  A + +P D PR
Sbjct: 372 IEQWRTRNCLGYNKDSGKIKPQAVIEALHRLTKGDAYVTSDVGQHQM-FAALYYPFDKPR 430

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + P   VV + GD +   +  E+ TA++  L ++++ 
Sbjct: 431 RWINSGGLGTMGFGLPAALGVKLALPNETVVCVTGDGSIQMNIQELSTALQYNLPVLVLN 490

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     +NT  EL      A+
Sbjct: 491 LNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVAINTPDELESKLADAL 550

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
                      ++V ++  E     QI     ++  L
Sbjct: 551 TQLSETNRLVFVDVTVDETEHVYPMQIRGGGMDEMWL 587
>ref|YP_441599.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           thailandensis E264]
 ref|ZP_02373280.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           thailandensis TXDOH]
 ref|ZP_02387147.1| acetolactate synthase 3 catalytic subunit [Burkholderia
           thailandensis Bt4]
 gb|ABC37149.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia thailandensis E264]
          Length = 587

 Score =  885 bits (2289), Expect = 0.0,   Method: Composition-based stats.
 Identities = 121/573 (21%), Positives = 228/573 (39%), Gaps = 30/573 (5%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGYIS 63
                 + L    ++ ++G  G  ++ + D +   + I+ +  R+EQAA +AA AY   +
Sbjct: 23  GATVLMKALADENVEFIWGYPGGSVLYIYDELYKQDKIQHVLVRHEQAAVHAADAYSRST 82

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            K GV L+  GPG+ +A+ GI  +  +  PL+VI+G    + I +  FQE D V +  P 
Sbjct: 83  GKVGVCLVTSGPGVTNAVTGIATAYMDSIPLVVISGQVPTAAIGQDAFQECDTVGITRPC 142

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
           +K    +     +    +KA      G  G   ID+P D  +     E        + + 
Sbjct: 143 VKHNFLVKDVRELAETVKKAFYIARTGRPGPVLIDIPKDISKTPCEYE----PVKNVSLR 198

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMA 242
               +      +I+K V L+L  K   I    G      S E+ +  +    P   T M 
Sbjct: 199 SYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGIILADASRELNQFADLLGYPVTNTLMG 258

Query: 243 KGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SIFI 294
            G    S         ++ +   + A++  D+++ +GAR +  +  G    + S     I
Sbjct: 259 LGGYRASDRKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRV-IGDPAHFASRPRKII 317

Query: 295 QFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLN 354
             D +P ++         D+ I GD+   +  L+E+L   +       + Q  ++ I+  
Sbjct: 318 HIDIDPSSISKR---VKVDIPIVGDVKEVLKDLIEQLQTAEHGPDADALAQWWKD-IEGW 373

Query: 355 QTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLD 414
           + +   K       +    V      L D    +    G + M  A+  +  + PRR ++
Sbjct: 374 RAKDCLKYDRESEIIKPQYVVEKAWELTDGNAFVCSDVGQHQMWAAQF-YRFNKPRRWIN 432

Query: 415 AGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS 474
           +G   TMG GL  A+  K +HP+ DV+ I G+ +      E+ T  +    + I+ +NN 
Sbjct: 433 SGGLGTMGFGLPAAMGVKMAHPDDDVLCITGEGSIQMCIQELSTCKQYDTPVKIISLNNR 492

Query: 475 --GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSR 530
             G+    + IE       + +     +  + +  G     +   +++    ++A+   R
Sbjct: 493 YLGMVRQWQQIEYSKRYSHSYMDALPDFVKLAQAYGHIGMRIEKSADVEPALKEAL---R 549

Query: 531 TKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
            K  T  ++   +P E       A     +  L
Sbjct: 550 LKDRTVFLDFQTDPTENVWPMVQAGKGITEMLL 582
>ref|ZP_01161985.1| acetolactate synthase III large subunit [Photobacterium sp. SKA34]
 gb|EAR54292.1| acetolactate synthase III large subunit [Photobacterium sp. SKA34]
          Length = 572

 Score =  885 bits (2289), Expect = 0.0,   Method: Composition-based stats.
 Identities = 120/581 (20%), Positives = 244/581 (41%), Gaps = 33/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASA 58
           M   +      + +   G+  +FG  G  ++ + D +   + I+ +  R+EQAA + A  
Sbjct: 1   MEMLSGADMIVRSMIDQGVKHIFGYPGGSVLDIYDALHEKSDIEHVLVRHEQAAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   +   GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGDVGVVLVTSGPGATNAITGIATAYMDSIPMVVLSGQVMSSLIGNDAFQECDMVG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +  P++I  I +KA      G  G   +D+P D +          +   
Sbjct: 121 ISRPVVKHSFLVTKPEDIPEIIKKAFYIASTGRPGPVVVDIPKDMLNP--AEAYPYQYPE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + +            +IK+ V+ +L  K   + +  G      S ++  L  + N+P +
Sbjct: 179 SISLRSYNPTTQGHKGQIKRGVKALLSAKKPVLYVGGGAIMSSCSEQLIELAESLNIPVV 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            T M  G  P S         ++ +   + A+  AD++  +G R +         K+  +
Sbjct: 239 NTLMGLGAFPGSHKQCLGMLGMHGTYEANMAMHNADLIFGIGVRFDDR-TTNNLEKYCPD 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I G     + ++++ L   +       + Q   + 
Sbjct: 298 ATIMHIDIDPSSISK---TVSADIPIVGSADTVLNSMLKLLKEHEVKNDQQEIAQWW-QS 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R      T   ++   QV   L  L +    +    G + M  A + +P D PR
Sbjct: 354 IESWRERECLSYDTDSDRIKPQQVIEVLHRLTNGEAYVSSDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  A+  K + P+ +VV + GD +   +  E+ TA++  + + I+ 
Sbjct: 413 RWINSGGLGTMGFGLPAAMGVKFALPDAEVVCVTGDGSIQMNIQELSTALQYDIPVKIIN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+  +G    + +     +  + +  G     ++  ++L    ++A+
Sbjct: 473 LNNRFLGMVKQWQDMIYQGRHSHSYMDSVPDFAAIAEAYGHVGVRISDPNKLESELEKAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
            L   K +   I++ ++  E           +   W +K  
Sbjct: 533 AL---KDKLVFIDISVDETEHVYPMLIRGGAMNEMWLSKTE 570
>ref|YP_927893.1| acetolactate synthase 3 catalytic subunit [Shewanella amazonensis
           SB2B]
 gb|ABM00224.1| acetolactate synthase large subunit [Shewanella amazonensis SB2B]
          Length = 573

 Score =  885 bits (2289), Expect = 0.0,   Method: Composition-based stats.
 Identities = 115/579 (19%), Positives = 227/579 (39%), Gaps = 31/579 (5%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANG-IKFIPCRNEQAASYAASAYG 60
             +      + L   G+  +FG  G  ++ + D +  +  I+ I  R+EQAA + A  Y 
Sbjct: 3   KLSGASMIVRSLIDEGVKHIFGYPGGSVLDIYDALHESSNIEHILVRHEQAAVHMADGYA 62

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
             +   GV+L+  GPG  +A+ GI  +  +  PL++++G    S I    FQE D + + 
Sbjct: 63  RATGDVGVVLVTSGPGATNAITGIATAYMDSVPLVILSGQVPSSLIGNDAFQECDMIGIS 122

Query: 121 SPFLKFTGKLTPD-NIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNEL 179
            P +K +  +     I    +KA      G  G   +D+P D +      +    +  E+
Sbjct: 123 RPIVKHSFLVKDPTEIPETIKKAFYIAATGRPGPVVVDLPKDTLNPALKFDYEYPS--EV 180

Query: 180 PMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPT 239
            M            +I++ +Q +L  K   + +  G        +I  L    N+P + T
Sbjct: 181 KMRSYNPTVTGHKGQIRRGLQALLNAKKPVLYVGGGAIISSCDKQILALSERLNIPVVNT 240

Query: 240 PMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESI 292
            M  G  P + P       ++ +   +  +  +D++  +G R +         K+   + 
Sbjct: 241 LMGLGAFPGTHPNNIGMLGMHGTYEANMTMHNSDLIFGIGVRFDDR-TTNNVQKYCPNAT 299

Query: 293 FIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQ 352
            +  D +P ++     +  A + I G     +  ++  L          G        I 
Sbjct: 300 VLHIDIDPSSISK---TVQAHIPIVGSADKVLDEMLSLLDGDTEMRNDEGAIDCWWNDIN 356

Query: 353 LNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRR 412
             ++R     +T   ++   QV  TL  L      +    G + M  A + +P D PRR 
Sbjct: 357 QWRSRKCLAYETNSEKIKPQQVIETLYRLTKGDAYVSSDVGQHQM-FAALYYPFDKPRRW 415

Query: 413 LDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMN 472
           +++G   TMG GL  A+  K + P+  VV + GD +   +  E+ TA++  + + I+ +N
Sbjct: 416 INSGGLGTMGFGLPAAMGVKMAMPDETVVCVTGDGSIQMNIQELSTALQYDVPVKIINLN 475

Query: 473 NS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQL 528
           N   G+    +D+   G    + +     +  + +  G     ++   EL     +A+ +
Sbjct: 476 NRFLGMVKQWQDMIYSGRHSHSYMDSVPDFAKIAEAYGHVGITISRPEELEPKLAEALSM 535

Query: 529 SRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
                    +++ ++  E           +   W +K  
Sbjct: 536 ---TDRLVFVDINVDETEHVYPMQIRGGAMNDMWLSKTE 571
>ref|YP_001906687.1| Acetolactate synthase isozyme III large subunit [Erwinia
           tasmaniensis]
 emb|CAO95789.1| Acetolactate synthase isozyme III large subunit [Erwinia
           tasmaniensis]
          Length = 574

 Score =  885 bits (2288), Expect = 0.0,   Method: Composition-based stats.
 Identities = 122/581 (20%), Positives = 239/581 (41%), Gaps = 31/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    G+  I  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALQTVGGVDHILVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   +   GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGDVGVVLVTSGPGATNAITGIATAYMDSIPMVVLSGQVMSSLIGYDAFQECDMVG 120

Query: 119 LLSPFLKFTGKLT-PDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   +D+P D +     L       +
Sbjct: 121 ISRPVVKHSFMVKRAEDIPTVMKKAFWLAASGRPGPVVVDLPKDMMNPANKL--PYVWPD 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
           E+ M            +IK+ +Q +L  KN  I    G        E+R+L  T N+P  
Sbjct: 179 EVSMRSYNPTTQGHKGQIKRALQTLLAAKNPVIYAGGGVINAACHDELRQLAETLNVPVT 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   +  +  +D++  +G R +         K+   
Sbjct: 239 TSLMGLGAFPGTHHQCLGMLGMHGTYEANMTMHHSDVIFAVGVRFDDR-TTNNLAKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +  ++E L +  +   +  ++    + 
Sbjct: 298 ATVLHIDIDPTSISK---TIAADVPIVGDAKQVLQQMLELLGQDPARQDFDALRDWW-QS 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  ++R   +      ++    V  T+  L      +    G + M  A + +  D PR
Sbjct: 354 IERWRSRHCLEFDRTSDKIKPQAVIETICRLTKGDAYVTSDVGQHQM-FAALYYQFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++  + ++++ 
Sbjct: 413 RWINSGGLGTMGFGLPAALGVKLALPDETVVCVTGDGSIQMNIQELSTALQYGIPVLVLN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     V    EL    +QA+
Sbjct: 473 LNNRVLGMVKQWQDMIYSGRHSQSYMESLPDFVRLAEAYGHVGISVTRPDELEAKLEQAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQKQ--------IAFAWQNKPR 559
           +    K     +++ ++  E           +   W +K  
Sbjct: 533 E-QLAKNRLVFVDINVDDSEHVYPMHIRGGGMDEMWLSKTE 572
>ref|NP_404181.1| acetolactate synthase 3 catalytic subunit [Yersinia pestis CO92]
 ref|YP_069216.1| acetolactate synthase 3 catalytic subunit [Yersinia
           pseudotuberculosis IP 32953]
 ref|YP_653467.1| acetolactate synthase 3 catalytic subunit [Yersinia pestis Antiqua]
 ref|YP_646339.1| acetolactate synthase 3 catalytic subunit [Yersinia pestis
           Nepal516]
 ref|ZP_01917153.1| acetolactate synthase isozyme III large subunit [Yersinia pestis
           CA88-4125]
 ref|YP_001402358.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis IP 31758]
 ref|NP_670937.2| acetolactate synthase 3 catalytic subunit [Yersinia pestis KIM]
 ref|NP_994917.2| acetolactate synthase 3 catalytic subunit [Yersinia pestis biovar
           Microtus str. 91001]
 ref|YP_001722251.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis YPIII]
 ref|YP_001871143.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis PB1/+]
 emb|CAH19915.1| acetolactate synthase III, valine sensitive, large subunit FAD and
           thiamine PPi binding [Yersinia pseudotuberculosis IP
           32953]
 gb|ABG16739.1| acetolactate synthase, large subunit [Yersinia pestis Nepal516]
 gb|ABG15522.1| acetolactate synthase, large subunit [Yersinia pestis Antiqua]
 emb|CAL19219.1| acetolactate synthase isozyme III large subunit [Yersinia pestis
           CO92]
 gb|EDM39910.1| acetolactate synthase isozyme III large subunit [Yersinia pestis
           CA88-4125]
 gb|ABS46825.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis IP 31758]
 gb|ACA69798.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis YPIII]
 gb|ACC87686.1| acetolactate synthase, large subunit, biosynthetic type [Yersinia
           pseudotuberculosis PB1/+]
          Length = 575

 Score =  884 bits (2287), Expect = 0.0,   Method: Composition-based stats.
 Identities = 123/577 (21%), Positives = 236/577 (40%), Gaps = 25/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGFDAFQECDMVG 120

Query: 119 LLSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I M+ +KA      G  G   ID+P D +     +        
Sbjct: 121 ISRPVVKHSFLVKRTEDIPMVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKM--PYAYPE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
           ++ +            +IK+ +Q I+  K   + +  G        E+  L    NLP  
Sbjct: 179 QVSLRSYNPTVQGHRGQIKRALQTIMAAKRPIMYVGGGAINAACHEELLILAEKLNLPVT 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   + A+   D++  +G R +         K+  +
Sbjct: 239 SSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYCPD 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +T +++ L++      +  ++    + 
Sbjct: 298 ATVLHIDIDPTSISK---TVTADIPIVGDAKQVLTQMLDLLSQVGCTQDFDSLRDWW-QS 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  +TR          ++    V   L  L      +    G + M  A + +P D PR
Sbjct: 354 IEQWRTRNCLGYNKDSGKIKPQAVIEALHRLTKGDAYVTSDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + P   VV + GD +   +  E+ TA++  L ++++ 
Sbjct: 413 RWINSGGLGTMGFGLPAALGVKLALPNETVVCVTGDGSIQMNIQELSTALQYNLPVLVLN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     +NT  EL      A+
Sbjct: 473 LNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVAINTPDELESKLADAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
                      ++V ++  E     QI     ++  L
Sbjct: 533 TQLSETNRLVFVDVTVDETEHVYPMQIRGGGMDEMWL 569
>ref|ZP_01770640.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia pseudomallei 305]
 gb|EBA44831.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia pseudomallei 305]
          Length = 587

 Score =  884 bits (2287), Expect = 0.0,   Method: Composition-based stats.
 Identities = 124/573 (21%), Positives = 228/573 (39%), Gaps = 30/573 (5%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGYIS 63
                 + L    ++ ++G  G  ++ + D +   + I+ +  R+EQAA +AA AY   +
Sbjct: 23  GATVLMKALADENVEFIWGYPGGSVLYIYDELYKQDKIQHVLVRHEQAAVHAADAYSRST 82

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            K GV L+  GPG+ +A+ GI  +  +  PL+VI+G    + I +  FQE D V +  P 
Sbjct: 83  GKVGVCLVTSGPGVTNAVTGIATAYMDSIPLVVISGQVPTAAIGQDAFQECDTVGITRPC 142

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
           +K    +     +    +KA      G  G   ID+P D  +     E        + + 
Sbjct: 143 VKHNFLVKDVRELAQTVKKAFYIARTGRPGPVLIDIPKDISKTPCEYE----PVKNVSLR 198

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMA 242
               +      +I+K V L+L  K   I    G      S E+ +  +    P   T M 
Sbjct: 199 SYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGIILADASRELNQFADLLGYPVTNTLMG 258

Query: 243 KGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SIFI 294
            G    S         ++ +   + A++  D+++ +GAR +  +  G    + S     I
Sbjct: 259 LGGYRSSDRKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRV-IGDPAHFASRPRKII 317

Query: 295 QFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLN 354
             D +P ++         D+ I GD+   +  L+E+L   +       + Q  +E I+  
Sbjct: 318 HIDIDPSSISKR---VKVDIPIVGDVKEVLKELIEQLQTAEHGPDADALAQWWKE-IEGW 373

Query: 355 QTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLD 414
           +     K       +    V   L  L D    +    G + M  A+  +  + PRR ++
Sbjct: 374 RGTDCLKYDRASEIIKPQYVVEKLWELTDGNAFVCSDVGQHQMWAAQF-YRFNKPRRWIN 432

Query: 415 AGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS 474
           +G   TMG GL  A+  K +HP+ DVV I G+ +      E+ T  +    + I+ +NN 
Sbjct: 433 SGGLGTMGFGLPAAMGVKMAHPDDDVVCITGEGSIQMCIQELSTCKQYDTPVKIISLNNR 492

Query: 475 --GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSR 530
             G+    + IE       + +     +  + +  G     +   +++    ++A+ L  
Sbjct: 493 YLGMIRQWQQIEYSKRYSHSYMDALPDFVKLAQAYGHIGMRIEKSADVEPALKEALSL-- 550

Query: 531 TKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
            K  T  ++   +P E       A     +  L
Sbjct: 551 -KDRTVFLDFQTDPTENVWPMVQAGKGITEMLL 582
>ref|ZP_01236581.1| acetolactate synthase III large subunit [Vibrio angustum S14]
 gb|EAS63234.1| acetolactate synthase III large subunit [Vibrio angustum S14]
          Length = 572

 Score =  884 bits (2285), Expect = 0.0,   Method: Composition-based stats.
 Identities = 119/581 (20%), Positives = 244/581 (41%), Gaps = 33/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASA 58
           M   +      + +   G+  +FG  G  ++ + D +   + I+ +  R+EQAA + A  
Sbjct: 1   MEMLSGADMIVRSMIDQGVKHIFGYPGGSVLDIYDALHEKSDIEHVLVRHEQAAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   +   GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGDVGVVLVTSGPGATNAITGIATAYMDSIPMVVLSGQVMSSLIGNDAFQECDMVG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +  P++I  I +KA      G  G   +D+P D +          +   
Sbjct: 121 ISRPVVKHSFLVTKPEDIPAIIKKAFYIASTGRPGPVVVDIPKDMLNP--AEAYPYQYPE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + +            +IK+ V+ +L  K   + +  G      S ++  L  + N+P +
Sbjct: 179 SISLRSYNPTTQGHKGQIKRGVKALLSAKKPVLYVGGGAIMSSCSEQLIELAESLNIPVV 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            T M  G  P +         ++ +   + A+  AD++  +G R +         K+  +
Sbjct: 239 NTLMGLGAFPGTHKQCLGMLGMHGTYEANMAMHNADLIFGIGVRFDDR-TTNNLEKYCPD 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I G     + ++++ L   +       + Q   + 
Sbjct: 298 ATIMHIDIDPSSISK---TVSADIPIVGSADTVLNSMLKLLKEHEVKNDQQEIAQWW-QS 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R      T   ++   QV   L  L +    +    G + M  A + +P D PR
Sbjct: 354 IESWRERECLSYDTDSDRIKPQQVIEVLHRLTNGEAYVSSDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  A+  K + P+ +VV + GD +   +  E+ TA++  + + I+ 
Sbjct: 413 RWINSGGLGTMGFGLPAAMGVKFALPDAEVVCVTGDGSIQMNIQELSTALQYDIPVKIIN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+  +G    + +     +  + +  G     ++  ++L    ++A+
Sbjct: 473 LNNRFLGMVKQWQDMIYQGRHSHSYMDSVPDFAAIAEAYGHVGVRISDPNKLESELEKAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
            L   K +   I++ ++  E           +   W +K  
Sbjct: 533 AL---KDKLVFIDISVDETEHVYPMLIRGGAMNEMWLSKTE 570
>ref|ZP_03831127.1| acetolactate synthase 3 catalytic subunit [Pectobacterium
           carotovorum subsp. carotovorum WPP14]
          Length = 572

 Score =  883 bits (2283), Expect = 0.0,   Method: Composition-based stats.
 Identities = 127/581 (21%), Positives = 242/581 (41%), Gaps = 33/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI+ I  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIEHILVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G  + S I    FQE D V 
Sbjct: 61  YARATGEVGVVLVTSGPGATNAITGIATAYMDSIPMVVLSGQVATSLIGYDSFQECDTVG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   +++  I +KA      G  G   +D+P D +     L        
Sbjct: 121 ISRPIVKHSFLVKKAEDVPTILKKAFYLASTGRPGPVVVDLPKDIMNPANKL--PYVYPE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +I++ +Q +L  +   I    G    +   E+  L    NLP  
Sbjct: 179 SISMRSYSPTVQGHKGQIRRALQTLLAAEKPIIYSGGGVINAECHEELLTLAEKLNLPVT 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   + A+  AD++  +G R +         K+   
Sbjct: 239 TSLMGLGGFPGTHRQCLGMLGMHGTYEANTAMHNADVIFAVGVRFDDR-TTNNLAKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    ++ ++E L +  +  ++  ++    + 
Sbjct: 298 ATVLHIDIDPASISK---TVNADIPIVGDAKQVLSLMLELLEQDGAPQQFDALRDWW-QG 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R   K  T   ++    V  TL  L +    +    G + M  A + +P D PR
Sbjct: 354 IEQWRGRHCLKYSTDSDKIKPQAVIETLHRLTEGKAYVASDVGQHQM-FAALYYPFDLPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + PE  V+ + GD +   +  E+ TA++  L +V++ 
Sbjct: 413 RWVNSGGLGTMGFGLPAALGIKLALPEETVICVTGDGSIQMNIQELSTALQYDLPVVVIN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++T  EL     QA+
Sbjct: 473 LNNRFLGMVKQWQDMIYSGRHSSSYMESLPDFVKLAEAYGHVGISIDTPDELESKLLQAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
                K     +++ I+  E           +   W +K  
Sbjct: 533 A---QKDRLVFVDINIDSSEHVYPMQIRGGAMDEMWLSKTE 570
>ref|YP_934657.1| acetolactate synthase [Azoarcus sp. BH72]
 emb|CAL95771.1| acetolactate synthase [Azoarcus sp. BH72]
          Length = 570

 Score =  883 bits (2283), Expect = 0.0,   Method: Composition-based stats.
 Identities = 119/577 (20%), Positives = 238/577 (41%), Gaps = 29/577 (5%)

Query: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTM-VANGIKFIPCRNEQAASYAASAY 59
           M  T  +   + LQ+  ++ VFG  G  ++ + D +     ++ +  R+EQAA +AA  +
Sbjct: 1   MVLTGAEIVIRCLQEEKVEYVFGYPGGAVLYIYDALFQQEQVRHVLVRHEQAAVHAADGF 60

Query: 60  GYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSL 119
              ++K GV L+  GPG  +A+ GI  +  +  P+++I+G    + I +  FQE+D V +
Sbjct: 61  ARSTEKVGVALVTSGPGATNAVTGIATAFCDSIPMVIISGQVPTAAIGQDAFQEVDTVGI 120

Query: 120 LSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNE 178
             P +K    +    +I    +KA      G  G   +D+P D    +   E       E
Sbjct: 121 TRPCVKHNFLVKDVRDIAATIKKAFYLAKTGRPGPVLVDIPKDITIAKCDFEY----PKE 176

Query: 179 LPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLP 238
           + M     +      +IKK VQL+L+ K   I    G      + ++ +L      P   
Sbjct: 177 ISMRSYSPVVKGHQGQIKKAVQLLLEAKRPMIYTGGGVVLANAAEQLTKLTRLLGFPVTN 236

Query: 239 TPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE- 290
           T M  G  P S         ++ +   + A+  +D++L +GAR +  +  G    +  E 
Sbjct: 237 TLMGLGGYPASDRQYLGMPGMHGTYEANMAMHYSDVLLAVGARFDDRV-IGNPANFAEEP 295

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
              I  D +P ++         D+ I GD+   +  ++ +L    +    S +    ++ 
Sbjct: 296 RKIIHIDIDPSSISKR---VKVDVPIVGDLKDVLDEMIRQLEAAPTRPDASNLAAWWKQ- 351

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           ++  ++R   + K     +    V   L  +      +    G + M  ++  +  D PR
Sbjct: 352 VEEWRSRKCMEYKNSDEIIKPQFVVQKLWEVTGGDAIVTSDVGQHQMWASQ-YYRFDKPR 410

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R L++G   TMG+GL YA+  + +HP++ V  + G+++      E+ T  + +L + I  
Sbjct: 411 RWLNSGGLGTMGVGLPYAMGAQFAHPDMPVACVTGEASIQMCIQELSTCKQFRLPIKICN 470

Query: 471 MNNS--GIYHGEKDIE--GDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    + +   G    + +     +  +    G     V+  +++    ++A 
Sbjct: 471 LNNRYLGMVRQWQQLFHGGRYSESYMDSLPDFAKLASAYGHVGIRVDKPADVEGALREAF 530

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
              +       ++  ++P E             +  L
Sbjct: 531 TTHKND--LVFLDFQVDPTENVYPMVQGGKGLTEMIL 565
>ref|YP_001791923.1| acetolactate synthase, large subunit, biosynthetic type [Leptothrix
           cholodnii SP-6]
 gb|ACB35158.1| acetolactate synthase, large subunit, biosynthetic type [Leptothrix
           cholodnii SP-6]
          Length = 592

 Score =  883 bits (2283), Expect = 0.0,   Method: Composition-based stats.
 Identities = 124/561 (22%), Positives = 228/561 (40%), Gaps = 28/561 (4%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANG-IKFIPCRNEQAASYAASAYG 60
               ++   + LQ  G+  ++G  G  ++ + D +     I+ +  R+EQAA +AA  Y 
Sbjct: 24  ELNGSEILVRCLQAEGVQYMWGYPGGSVLYIYDALYKQDTIQHVLVRHEQAAVHAADGYA 83

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
             +   GV L+  GPG+ +A+ GI  +  +  P+++I G      I    FQE D V + 
Sbjct: 84  RATGDVGVALVTSGPGVTNAVTGIATAYMDSIPMVIITGQVPTPAIGLDAFQECDTVGIT 143

Query: 121 SPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNEL 179
            P +K    +    ++ +  +KA +    G  G   ID+P D    +            +
Sbjct: 144 RPIVKHNFLVKDVRDLALTIKKAFHIARTGRPGPVVIDIPKDVSLNKTAFHY----PETV 199

Query: 180 PMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPT 239
            M     +      +I+K VQL+L  K   I    G      S E+R L +    P   T
Sbjct: 200 EMRSYNPVRKGHGGQIRKAVQLLLGAKRPYIYTGGGVILGNASAELRELADLLGYPVTNT 259

Query: 240 PMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNS-ES 291
            M  G +P + P       ++ +   +  ++  D++L +GAR +  +  G    + S E 
Sbjct: 260 LMGLGAMPATDPRFLGMLGMHGTYEANMTMQNCDVLLAVGARFDDRV-IGNPKHFASVER 318

Query: 292 IFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKI 351
             I  D +P ++         D+ I GD+   +  L+ ++       + + +      +I
Sbjct: 319 KIIHVDIDPSSISKR---VKVDIPIVGDVKDVLQELIAQIRESQQRAEPAALNAWW-SQI 374

Query: 352 QLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDD-YRTILVTEGANTMDIARISFPTDAPR 410
              + +     K     +    V  TL  L       I    G + M  A+  F  D PR
Sbjct: 375 NDWRKQDCLSYKGSDEVIKPQFVVETLWNLTRGSDSYITSDVGQHQMWAAQ-YFKFDEPR 433

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG+GL YA+  K + P+ DV  I G+ +   +  E+ T  +    + ++ 
Sbjct: 434 RWINSGGLGTMGVGLPYAMGIKLAKPDADVFCITGEGSIQMNIQELSTCQQYSTPVKVIA 493

Query: 471 MNNS--GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    + +E       + +     +  + +  G     +   SE+    ++  
Sbjct: 494 LNNRYLGMVRQWQQLEYSSRYSHSYMDALPDFVKLAEAYGHIGLKIERPSEVEPALKE-- 551

Query: 527 QLSRTKRETSVINVIIEPGEQ 547
            L R K  T  ++V  +P E 
Sbjct: 552 -LIRLKDRTVFLDVRTDPTEN 571
>ref|YP_001366575.1| acetolactate synthase, large subunit, biosynthetic type [Shewanella
           baltica OS185]
 gb|ABS08512.1| acetolactate synthase, large subunit, biosynthetic type [Shewanella
           baltica OS185]
          Length = 572

 Score =  882 bits (2281), Expect = 0.0,   Method: Composition-based stats.
 Identities = 118/581 (20%), Positives = 230/581 (39%), Gaps = 33/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +      + L   G+  +FG  G  ++ + D +    GI+ I  R+EQAA + A  
Sbjct: 1   MEMLSGASMIVRSLIDEGVKHIFGYPGGSVLDIYDALHVIPGIEHILVRHEQAAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + K GV+L+  GPG  +A+ GI  +  +  PL+V++G    + I    FQE D + 
Sbjct: 61  YARATGKVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQVPSNLIGNDAFQECDMIG 120

Query: 119 LLSPFLKFTGKLTPD-NIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +     I  I +KA      G  G   +D+P D +      E       
Sbjct: 121 ISRPVVKHSFLVKDPTEIPEIIKKAFYIASTGRPGPVVVDLPKDCLNPALLHEYCY--PE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +I++ +Q +L  K   + +  G        +I +L    N+P +
Sbjct: 179 SVKMRSYNPTTSGHKGQIRRGLQALLAAKKPVLYVGGGAIISGCDKQILQLAERLNIPVV 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            T M  G  P +         ++     +  +   D++  +G R +         K+   
Sbjct: 239 STLMGLGAFPSTHKNSLGMLGMHGRYEANMTMHNCDLIFGIGVRFDDR-TTNNVEKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +   D+ I G     + +++  L   +       +     + 
Sbjct: 298 ATILHIDIDPSSISK---TVRVDIPIVGSADSILDSMLALLDESNEHNDSDAIATWWND- 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  ++R          ++   QV  TL  L +    +    G + M  A + +P D PR
Sbjct: 354 IEQWRSRDCLAYDKSSGRIKPQQVIETLYKLTNGDAYVASDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  A+  K + P+  VV + GD +   +  E+ TA++    + I+ 
Sbjct: 413 RWINSGGLGTMGFGLPAAMGVKMAMPDATVVCVTGDGSIQMNIQELSTALQYDTPVKIIN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++  +EL     +A+
Sbjct: 473 LNNRFLGMVKQWQDMIYSGRHSHSYMDSVPNFAKIAEAYGHVGMTISDPAELESKMAEAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
            +   K     I+++++  E           +   W  K  
Sbjct: 533 AM---KDRLVFIDIMVDETEHVYPMLIRGGAMNEMWLTKTE 570
>ref|YP_001894967.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia phytofirmans PsJN]
 gb|ACD15743.1| acetolactate synthase, large subunit, biosynthetic type
           [Burkholderia phytofirmans PsJN]
          Length = 587

 Score =  882 bits (2281), Expect = 0.0,   Method: Composition-based stats.
 Identities = 118/557 (21%), Positives = 228/557 (40%), Gaps = 27/557 (4%)

Query: 5   ATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGYIS 63
                 + L    ++ V+G  G  ++ + D +   +  + I  R+EQAA +AA AY   +
Sbjct: 23  GATVLMKALADEDVEFVWGYPGGSVLYIYDELYKQDKFQHILVRHEQAAVHAADAYSRST 82

Query: 64  DKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPF 123
            K GV L+  GPG+ +A+ GI  +  +  P++VI+G    + I +  FQE D V +  P 
Sbjct: 83  GKVGVCLVTSGPGVTNAVTGIATAYMDSIPMVVISGQVPTAAIGQDAFQECDTVGITRPC 142

Query: 124 LKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMI 182
           +K    +    ++    +KA      G  G   ID+P D  +     E        + + 
Sbjct: 143 VKHNFLVKDVRDLAATVKKAFFIARTGRPGPVLIDIPKDVSKAPCQYE----PLKTVSLR 198

Query: 183 LTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMA 242
               +      +I+K V L+L  K   I    G      S E+ +  +    P   T M 
Sbjct: 199 SYNPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGIILADASRELNQFADLLGYPVTNTLMG 258

Query: 243 KGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SIFI 294
            G    S         ++ +   + A++  D+++ +GAR +  +  G    ++S     I
Sbjct: 259 LGGYRASDKKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRV-IGDPAHFSSRPRKII 317

Query: 295 QFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLN 354
             D +P ++         D+ I GD+   +  L+E+L   +     + +    ++ I+  
Sbjct: 318 HIDIDPSSISKR---VKVDIPIVGDVKEVLKELIEQLQTAEHGPDTAALADWWKD-IEAW 373

Query: 355 QTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLD 414
           + +   K   +   +    V      L D    +    G + M  A+  +  + PRR ++
Sbjct: 374 RAKDCLKFDRKSDIIKPQYVVEKAWELTDGNAFVCSDVGQHQMWAAQF-YRFNKPRRWIN 432

Query: 415 AGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS 474
           +G   TMG GL  A+  K +HP+ DV+ I G+ +      E+ T  + +  + I+ +NN 
Sbjct: 433 SGGLGTMGFGLPAAMGVKMAHPDDDVLCITGEGSIQMCIQELSTCKQYETPVKIISLNNR 492

Query: 475 --GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSR 530
             G+    + IE       + +     +  + +  G     +   +++    ++A+   R
Sbjct: 493 YLGMVRQWQQIEYSKRYSHSYMDALPDFVKLAEAYGHVGMRIERTADVEPALKEAL---R 549

Query: 531 TKRETSVINVIIEPGEQ 547
            K  T  ++   +P E 
Sbjct: 550 LKDRTVFLDFQTDPTEN 566
>ref|YP_001050748.1| acetolactate synthase 3 catalytic subunit [Shewanella baltica
           OS155]
 gb|ABN61879.1| acetolactate synthase, large subunit [Shewanella baltica OS155]
          Length = 572

 Score =  882 bits (2280), Expect = 0.0,   Method: Composition-based stats.
 Identities = 118/581 (20%), Positives = 231/581 (39%), Gaps = 33/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +      + L   G+  +FG  G  ++ + D +    GI+ I  R+EQAA + A  
Sbjct: 1   MEMLSGASMIVRSLIDEGVKHIFGYPGGSVLDIYDALHVIPGIEHILVRHEQAAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + K GV+L+  GPG  +A+ GI  +  +  PL+V++G    + I    FQE D + 
Sbjct: 61  YARATGKVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQVPSNLIGNDAFQECDMIG 120

Query: 119 LLSPFLKFTGKLTPD-NIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +     I  I +KA      G  G   +D+P D +      E       
Sbjct: 121 ISRPVVKHSFLVKDPTEIPEIIKKAFYIASTGRPGPVVVDLPKDCLNPALLHEYCY--PE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +I++ +Q +L  K   + +  G        +I +L    N+P +
Sbjct: 179 SVKMRSYNPTTSGHKGQIRRGLQALLAAKKPVLYVGGGAIISGCDKQILQLAERLNIPVV 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            T M  G  P +         ++     +  +   D++  +G R +         K+   
Sbjct: 239 STLMGLGAFPSTHKNSLGMLGMHGRYEANMTMHNCDLIFGIGVRFDDR-TTNNVEKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +   D+ I G     + +++ +L   +       +     + 
Sbjct: 298 ATILHIDIDPSSISK---TIHVDIPIVGSADSILDSMLAQLDESNEHNDNDAIATWWND- 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  ++R          ++   QV  TL  L +    +    G + M  A + +P D PR
Sbjct: 354 IEQWRSRDCLAYDKNSGRIKPQQVIETLYKLTNGDAYVASDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  A+  K + P+  VV + GD +   +  E+ TA++    + I+ 
Sbjct: 413 RWINSGGLGTMGFGLPAAMGVKMAMPDATVVCVTGDGSIQMNIQELSTALQYDTPVKIIN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++  +EL     +A+
Sbjct: 473 LNNRFLGMVKQWQDMIYSGRHSHSYMDSVPNFAKIAEAYGHVGMTISDPAELESKMAEAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
            +   K     I+++++  E           +   W  K  
Sbjct: 533 AM---KDRLVFIDIMVDETEHVYPMLIRGGAMNEMWLTKTE 570
>ref|YP_001554918.1| acetolactate synthase, large subunit, biosynthetic type [Shewanella
           baltica OS195]
 gb|ABX49658.1| acetolactate synthase, large subunit, biosynthetic type [Shewanella
           baltica OS195]
          Length = 572

 Score =  881 bits (2279), Expect = 0.0,   Method: Composition-based stats.
 Identities = 118/581 (20%), Positives = 230/581 (39%), Gaps = 33/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +      + L   G+  +FG  G  ++ + D +    GI+ I  R+EQAA + A  
Sbjct: 1   MEMLSGASMIVRSLIDEGVKHIFGYPGGSVLDIYDALHVIPGIEHILVRHEQAAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + K GV+L+  GPG  +A+ GI  +  +  PL+V++G    + I    FQE D + 
Sbjct: 61  YARATGKVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQVPSNLIGNDAFQECDMIG 120

Query: 119 LLSPFLKFTGKLTPD-NIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +     I  I +KA      G  G   +D+P D +      E       
Sbjct: 121 ISRPVVKHSFLVKDPTEIPEIIKKAFYIASTGRPGPVVVDLPKDCLNPALLHEYCY--PE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +I++ +Q +L  K   + +  G        +I +L    N+P +
Sbjct: 179 SVKMRSYNPTTSGHKGQIRRGLQALLAAKKPVLYVGGGAIISGCDKQILQLAERLNIPVV 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            T M  G  P +         ++     +  +   D++  +G R +         K+   
Sbjct: 239 STLMGLGAFPSTHKNCLGMLGMHGRYEANMTMHNCDLIFGIGVRFDDR-TTNNVEKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +   D+ I G     + +++  L   +       +     + 
Sbjct: 298 ATILHIDIDPSSISK---TIHVDIPIVGSADSILDSMLALLDESNEHNDNDAIATWWND- 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  ++R          ++   QV  TL  L +    +    G + M  A + +P D PR
Sbjct: 354 IEQWRSRDCLAYDKNSGRIKPQQVIETLYKLTNGDAYVASDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  A+  K + P+  VV + GD +   +  E+ TA++    + I+ 
Sbjct: 413 RWINSGGLGTMGFGLPAAMGVKMAMPDATVVCVTGDGSIQMNIQELSTALQYDTPVKIIN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++  +EL     +A+
Sbjct: 473 LNNRFLGMVKQWQDMIYSGRHSHSYMDSVPNFAKIAEAYGHVGMTISDPAELESKMAEAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
            +   K     I+++++  E           +   W  K  
Sbjct: 533 AM---KDRLVFIDIMVDETEHVYPMLIRGGAMNEMWLTKTE 570
>ref|YP_051917.1| acetolactate synthase 3 catalytic subunit [Erwinia carotovora
           subsp. atroseptica SCRI1043]
 emb|CAG76727.1| acetolactate synthase isozyme III large subunit [Erwinia carotovora
           subsp. atroseptica SCRI1043]
          Length = 572

 Score =  881 bits (2279), Expect = 0.0,   Method: Composition-based stats.
 Identities = 127/581 (21%), Positives = 242/581 (41%), Gaps = 33/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI+ I  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIEHILVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G  + S I    FQE D V 
Sbjct: 61  YARATGEVGVVLVTSGPGATNAITGIATAYMDSIPMVVLSGQVATSLIGYDSFQECDTVG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   +++  I +KA      G  G   +D+P D +     L        
Sbjct: 121 ISRPIVKHSFLVKKAEDVPTILKKAFYLASTGRPGPVVVDLPKDIMSPANKL--PYVYPE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +I++ +Q +L  +   I    G    +   E+  L    NLP  
Sbjct: 179 SVSMRSYSPTVQGHKGQIRRALQTLLAAEKPIIYSGGGVINAECHEELLTLAEKLNLPVT 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   + A+  AD++  +G R +         K+   
Sbjct: 239 TSLMGLGGFPGTHRQCLGMLGMHGTYEANLAMHNADVIFAVGVRFDDR-TTNNLAKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    ++ ++E L +  +  ++  ++    + 
Sbjct: 298 ATVLHIDIDPASISK---TVNADIPIVGDAKQVLSLMLELLAQDGAQQQFDALRDWW-QG 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R   K  T   ++    V  TL  L +    +    G + M  A + +P D PR
Sbjct: 354 IEQWRGRHCLKYNTESDKIKPQAVIETLHRLTEGKAYVASDVGQHQM-FAALYYPFDLPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + PE  V+ + GD +   +  E+ TA++  L +V++ 
Sbjct: 413 RWVNSGGLGTMGFGLPAALGIKLALPEETVICVTGDGSIQMNIQELSTALQYDLPVVVIN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++T  EL     QA+
Sbjct: 473 LNNRFLGMVKQWQDMIYSGRHSSSYMESLPDFVKLAEAYGHVGISIDTPDELESKLSQAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
                K     +++ I+  E           +   W +K  
Sbjct: 533 A---QKDRLVFVDINIDSSEHVYPMQIRGGAMDEMWLSKTE 570
>ref|ZP_03827861.1| acetolactate synthase 3 catalytic subunit [Pectobacterium
           carotovorum subsp. brasiliensis PBR1692]
          Length = 572

 Score =  881 bits (2278), Expect = 0.0,   Method: Composition-based stats.
 Identities = 130/581 (22%), Positives = 243/581 (41%), Gaps = 33/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI+ I  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIEHILVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G  + S I    FQE D V 
Sbjct: 61  YARATGEVGVVLVTSGPGATNAITGIATAYMDSIPMVVLSGQVATSLIGYDSFQECDTVG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   +++  I +KA      G  G   +D+P D +     L        
Sbjct: 121 ISRPIVKHSFLVKKAEDVPTILKKAFYLASTGRPGPVVVDLPKDVMNPANKL--PYVYPE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +I++ +Q +L  K   I    G    +   E+  L    NLP  
Sbjct: 179 SVSMRSYNPTVQGHKGQIRRALQTLLAAKKPIIYSGGGVINAECHEELLTLAEKLNLPVT 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   + A+  AD++  +G R +         K+   
Sbjct: 239 TSLMGLGGFPGTHRQCLGMLGMHGTYEANTAMHNADVIFAVGVRFDDR-TTNNLAKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +T ++E L +  +  ++  ++    + 
Sbjct: 298 ATVLHIDVDPASISK---TVNADIPIVGDAKQVLTLMLELLAQDGAQQQFDALRDWW-QG 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R   K  T G ++    V  TL  L +    +    G + M  A + +P D PR
Sbjct: 354 IEQWRGRHCLKYSTEGDKIKPQAVIETLHRLTEGKAYVASDVGQHQM-FAALYYPFDLPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + PE  V+ + GD +   +  E+ TA++  L +V++ 
Sbjct: 413 RWVNSGGLGTMGFGLPAALGIKLALPEETVICVTGDGSIQMNIQELSTALQYDLPVVVIN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++T  EL     QA+
Sbjct: 473 LNNRFLGMVKQWQDMIYSGRHSSSYMESLPDFVKLAEAYGHIGISIDTPDELESKLSQAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
                K     +++ I+  E           +   W +K  
Sbjct: 533 A---QKDRLVFVDINIDSSEHVYPMQIRGGAMDEMWLSKTE 570
>ref|YP_001164433.1| acetolactate synthase 3 catalytic subunit [Yersinia pestis
           Pestoides F]
 gb|ABP41460.1| acetolactate synthase, large subunit [Yersinia pestis Pestoides F]
          Length = 575

 Score =  881 bits (2278), Expect = 0.0,   Method: Composition-based stats.
 Identities = 122/577 (21%), Positives = 235/577 (40%), Gaps = 25/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQ A + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKHVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQGAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + + GV+L+  GPG  +A+ GI  +  +  P++V++G    S I    FQE D V 
Sbjct: 61  YARATGEVGVVLVTSGPGATNAITGIATAYMDSVPMVVLSGQVPSSLIGFDAFQECDMVG 120

Query: 119 LLSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I M+ +KA      G  G   ID+P D +     +        
Sbjct: 121 ISRPVVKHSFLVKRTEDIPMVLKKAFYLASTGRPGPVVIDLPKDIVGPAVKM--PYAYPE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
           ++ +            +IK+ +Q I+  K   + +  G        E+  L    NLP  
Sbjct: 179 QVSLRSYNPTVQGHRGQIKRALQTIMAAKRPIMYVGGGAINAACHEELLILAEKLNLPVT 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   + A+   D++  +G R +         K+  +
Sbjct: 239 SSLMGLGSFPGTHRQSVGMLGMHGTFEANMAMHNTDLIFAVGVRFDDR-TTNNLAKYCPD 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +T +++ L++      +  ++    + 
Sbjct: 298 ATVLHIDIDPTSISK---TVTADIPIVGDAKQVLTQMLDLLSQVGCTQDFDSLRDWW-QS 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  +TR          ++    V   L  L      +    G + M  A + +P D PR
Sbjct: 354 IEQWRTRNCLGYNKDSGKIKPQAVIEALHRLTKGDAYVTSDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + P    V + GD +   +  E+ TA++  L ++++ 
Sbjct: 413 RWINSGGLGTMGFGLPAALGVKLALPNETAVCVTGDGSIQMNIQELSTALQYNLPVLVLN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     +NT  EL      A+
Sbjct: 473 LNNRYLGMVKQWQDMIYSGRHSQSYMDSLPDFVKLAEAYGHIGVAINTPDELESKLADAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
                      ++V ++  E     QI     ++  L
Sbjct: 533 TQLSETNRLVFVDVTVDETEHVYPMQIRGGGMDEMWL 569
>ref|NP_520198.1| acetolactate synthase 3 catalytic subunit [Ralstonia solanacearum
           GMI1000]
 emb|CAD15784.1| probable acetolactate synthase isozyme III (large subunit) protein
           [Ralstonia solanacearum]
          Length = 585

 Score =  881 bits (2277), Expect = 0.0,   Method: Composition-based stats.
 Identities = 119/560 (21%), Positives = 231/560 (41%), Gaps = 27/560 (4%)

Query: 2   TTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYG 60
               +      L   G++ V+G  G  ++ + D     N I+ I  R+EQAA +AA  Y 
Sbjct: 18  EMMGSDILVNALAAEGVEFVWGYPGGAVLYIYDAFYKQNKIEHILVRHEQAAVHAADGYA 77

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
             + K GV L+  GPG+ +A+ GI  +  +  P+++I G+     I +  FQE D V + 
Sbjct: 78  RATGKVGVALVTSGPGVTNAVTGIATAYLDSIPMVIITGNVPTHAIGQDAFQECDTVGIT 137

Query: 121 SPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNEL 179
            P +K    +    N+    +KA      G  G   +D+P D        E        +
Sbjct: 138 RPIVKHNFLVKDVRNLASTIKKAFYIASTGRPGPVVVDIPKDVSRELCKYEY----PKTI 193

Query: 180 PMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPT 239
            M     +      +I+K V L+LQ +   I    G      S E+R+L      P   T
Sbjct: 194 EMRSYNPVNKGHSGQIRKAVSLLLQAERPYIYTGGGVVLANASEELRQLAALTGYPVTNT 253

Query: 240 PMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-S 291
            M  G  P +S        ++ +   + A++  D+++ +GAR +  +  G+   + S+  
Sbjct: 254 LMGLGAFPGASKQFLGMLGMHGTYEANMAMQHCDVLIAVGARFDDRV-IGSPAHFASQPR 312

Query: 292 IFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKI 351
             I  D +P ++         D+ I G++   +  ++ ++   ++    + + +   E+I
Sbjct: 313 KIIHIDIDPSSISKR---VKVDIPIVGNVKDVLQEMIAQIQAGEAKPNKTALAKWW-EQI 368

Query: 352 QLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRR 411
           +  ++    K       +    V   +  L      +    G + M  A+  +  + PRR
Sbjct: 369 EQWRSVDCLKYDRTSEIIKPQYVVEKIWELTAGDAFVCSDVGQHQMWAAQF-YKFNEPRR 427

Query: 412 RLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVM 471
            +++G   TMG+GL YA+  K + P+ +VV I G+ +      E+ T ++    + I  +
Sbjct: 428 WINSGGLGTMGVGLPYAMGVKKAFPDKEVVTITGEGSIQMCIQELSTCLQYDTPVKICSL 487

Query: 472 NNS--GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQ 527
           NN   G+    ++IE       + +     +  + +  G     +   +++    ++A  
Sbjct: 488 NNGYLGMVRQWQEIEYDNRYSHSYMQALPDFVKLAEAYGHVGMRIEKTADVEPALREAF- 546

Query: 528 LSRTKRETSVINVIIEPGEQ 547
             R K  T  ++   +P E 
Sbjct: 547 --RLKDRTVFLDFQTDPTEN 564
>gb|AAN78592.1|AE016755_92 Acetolactate synthase isozyme III large subunit [Escherichia coli
           CFT073]
          Length = 604

 Score =  880 bits (2276), Expect = 0.0,   Method: Composition-based stats.
 Identities = 125/577 (21%), Positives = 244/577 (42%), Gaps = 26/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQAA + A  
Sbjct: 31  MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQAAVHMADG 90

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
               + + GV+L+  GPG  +A+ GI  +  +  PL+V++G  + S I    FQE D V 
Sbjct: 91  LARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVG 150

Query: 119 LLSPFLKFTGKLT-PDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   +D+P D +     L        
Sbjct: 151 ISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDLPKDILNPANKL--PYVWPE 208

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +IK+ +Q ++  K   + +  G        +++  V   NLP +
Sbjct: 209 SVSMRSYNPTTSGHKGQIKRALQTLVAAKKPVVYVGGGAITAGCHLQLKEAVEVLNLPVV 268

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   +  +  AD++  +G R +         K+   
Sbjct: 269 SSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVIFAVGVRFDDR-TTNNLAKYCPN 327

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +  ++E L+++ +      ++    ++
Sbjct: 328 ATVLHIDIDPTSISK---TVTADIPIVGDARQVLEQMLELLSQESAHQPLDEIRDWW-QQ 383

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R   K  T   ++    V  TL  L +    +    G + M  A + +P D PR
Sbjct: 384 IEQWRARQCLKYDTHSEKIKPQAVIETLWRLTNGDAYVTSDVGQHQM-FAALYYPFDKPR 442

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + PE  VV + GD +   +  E+ TA++ +L +++V 
Sbjct: 443 RWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVVN 502

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++   EL     +A+
Sbjct: 503 LNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLAEAYGHVGIQISHPQELESKLSEAL 562

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
           +  R       ++V ++  E     QI     ++  L
Sbjct: 563 EQVRN-NRLVFVDVTVDGSEHVYPMQIRGGGMDEMWL 598
>ref|YP_001742200.1| acetolactate synthase, large subunit, isozyme III [Escherichia coli
           SMS-3-5]
 gb|ACB18938.1| acetolactate synthase, large subunit, isozyme III [Escherichia coli
           SMS-3-5]
          Length = 604

 Score =  880 bits (2276), Expect = 0.0,   Method: Composition-based stats.
 Identities = 124/577 (21%), Positives = 241/577 (41%), Gaps = 26/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQAA + A  
Sbjct: 31  MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQAAVHMADG 90

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
               + + GV+L+  GPG  +A+ GI  +  +  PL+V++G  + S I    FQE D V 
Sbjct: 91  LARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVG 150

Query: 119 LLSPFLKFTGKLT-PDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   +D+P D +     L        
Sbjct: 151 ISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDLPKDILNPANKL--PYVWPE 208

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +IK+ +Q ++  K   + +  G        +++  V   NLP +
Sbjct: 209 SVSMRSYNPTTSGHKGQIKRALQTLVAAKKPVVYVGGGAITAGCHQQLKETVEALNLPVV 268

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   +  +  AD++  +G R +         K+   
Sbjct: 269 SSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVIFAVGVRFDDR-TTNNLAKYCPN 327

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +  + E L+++        ++    ++
Sbjct: 328 ATVLHIDIDPTSISK---TVTADIPIVGDARQVLEQMFELLSQESVHQPLDEIRDWW-QQ 383

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R   K  +   ++    V  TL  L      +    G + M  A + +P D PR
Sbjct: 384 IEQWRARQCLKYDSHSEKIKPQAVIETLWRLTKGDAYVTSDVGQHQM-FAALYYPFDKPR 442

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + PE  VV + GD +   +  E+ TA++ +L +++V 
Sbjct: 443 RWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVVN 502

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++   EL     +A+
Sbjct: 503 LNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLAEAYGHVGIQISHPQELESKLSEAL 562

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
           +  R       ++V ++  E     QI     ++  L
Sbjct: 563 EQVRN-NRLVFVDVTVDGSEHVYPMQIRGGGMDEMWL 598
>ref|YP_002806680.1| acetolactate synthase [Escherichia sp. 1_1_43]
 gb|EEH72600.1| acetolactate synthase [Escherichia sp. 1_1_43]
          Length = 602

 Score =  880 bits (2275), Expect = 0.0,   Method: Composition-based stats.
 Identities = 125/577 (21%), Positives = 243/577 (42%), Gaps = 26/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQAA + A  
Sbjct: 29  MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQAAVHMADG 88

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
               + + GV+L+  GPG  +A+ GI  +  +  PL+V++G  + S I    FQE D V 
Sbjct: 89  LARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVG 148

Query: 119 LLSPFLKFTGKLT-PDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   +D+P D +     L        
Sbjct: 149 ISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDLPKDILNPANKL--PYVWPE 206

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +IK+ +Q ++  K   + +  G        +++  V   NLP +
Sbjct: 207 SVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAITAGCHQQLKETVEALNLPVV 266

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   +  +  AD++  +G R +         K+   
Sbjct: 267 CSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVIFAVGVRFDDR-TTNNLAKYCPN 325

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +  ++E L+++ +      ++    ++
Sbjct: 326 ATVLHIDIDPTSISK---TVTADIPIVGDARQVLEQMLELLSQESAHQPLDEIRDWW-QQ 381

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R   K  T   ++    V  TL  L      +    G + M  A + +P D PR
Sbjct: 382 IEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGDAYVTSDVGQHQM-FAALYYPFDKPR 440

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + PE  VV + GD +   +  E+ TA++ +L +++V 
Sbjct: 441 RWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVVN 500

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++   EL     +A+
Sbjct: 501 LNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLAEAYGHVGIQISHPHELESKLSEAL 560

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
           +  R       ++V ++  E     QI     ++  L
Sbjct: 561 EQVRN-NRLVFVDVTVDGSEHVYPMQIRGGGMDEMWL 596
>ref|ZP_02844546.1| acetolactate synthase, large subunit, biosynthetic type [Thauera
           sp. MZ1T]
 gb|EDS55584.1| acetolactate synthase, large subunit, biosynthetic type [Thauera
           sp. MZ1T]
          Length = 570

 Score =  880 bits (2275), Expect = 0.0,   Method: Composition-based stats.
 Identities = 120/577 (20%), Positives = 239/577 (41%), Gaps = 29/577 (5%)

Query: 1   MTTTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANG-IKFIPCRNEQAASYAASAY 59
           M  +  +   + LQ+  ++ VFG  G  ++ L D +     ++ +  R+EQAA +AA  +
Sbjct: 1   MVLSGAEIVIRCLQEEKVEYVFGYPGGAVLFLYDALFQQETVRHVLVRHEQAAVHAADGF 60

Query: 60  GYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSL 119
              ++K GV L+  GPG  +A+ GI  +  +  P+++I+G    + I +  FQE+D V +
Sbjct: 61  ARSTEKVGVALVTSGPGATNAVTGIATAYCDSIPMVIISGQVPVAAIGQDAFQEVDTVGI 120

Query: 120 LSPFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNE 178
             P +K    +    +I    +KA +    G  G   +D+P D        E       E
Sbjct: 121 TRPCVKHNFLVRDVRDIAATMKKAFHLARTGRPGPVLVDIPKDVSMQRCEYEY----PKE 176

Query: 179 LPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLP 238
           + M     +      +IKK VQL+L+ K   I    G      + ++ +L      P   
Sbjct: 177 ISMRSYNPVTKGHSGQIKKAVQLLLEAKRPMIYTGGGVVLSNAAEQLVKLTRLLGYPITN 236

Query: 239 TPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE- 290
           T M  G  P S         ++ +   + A+  +D++L +GAR +  +  G    +  E 
Sbjct: 237 TLMGLGGYPSSDRQFLGMPGMHGTFEANMAMHYSDVLLAVGARFDDRV-IGNPAHFAEEP 295

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
              I  D +P ++         D  I GD+   +  ++ ++   ++      +    ++ 
Sbjct: 296 RKIIHVDIDPSSISKR---VRVDTPIVGDVKEVLDEMIRQIESGEARPNPEALASWWKQ- 351

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R     K     +    V   L  +      +    G + M  A+  +  D PR
Sbjct: 352 IEQWRERKCMVYKNSDEIIKPQFVIQKLWEVTGGDAIVTSDVGQHQMWAAQ-YYGFDKPR 410

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R L++G   TMG+G+ YA+  K ++P++ V  + G+++   +  E+ T  + +L + I  
Sbjct: 411 RWLNSGGLGTMGVGMPYAMGAKLANPDMQVACVTGEASIQMNIQELSTCKQFRLPIKICN 470

Query: 471 MNNS--GIYHGEKDIE--GDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +++   G    + +     +  + +  G     V+  +++    ++A 
Sbjct: 471 LNNRYLGMVRQWQELFHGGRYSESYMDSLPDFAKLAESYGHVGIRVDRPADVEGALREAF 530

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
             +  K E   ++  I+  E             +  L
Sbjct: 531 --TTHKDELVFLDFQIDQTENVYPMVQGGKGLTEMIL 565
>ref|NP_759633.1| acetolactate synthase 3 catalytic subunit [Vibrio vulnificus CMCP6]
 ref|NP_933288.1| acetolactate synthase 3 catalytic subunit [Vibrio vulnificus YJ016]
 gb|AAO09160.1|AE016799_58 Thiamine pyrophosphate-requiring enzymes ; COG0028 [Vibrio
           vulnificus CMCP6]
 dbj|BAC93259.1| thiamine pyrophosphate-requiring enzyme [Vibrio vulnificus YJ016]
          Length = 574

 Score =  879 bits (2273), Expect = 0.0,   Method: Composition-based stats.
 Identities = 133/575 (23%), Positives = 242/575 (42%), Gaps = 28/575 (4%)

Query: 3   TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA--NGIKFIPCRNEQAASYAASAYG 60
            +  +   Q L +  ++ +FG  G  ++ + D + A    IK +  R+EQAA++ A  Y 
Sbjct: 5   LSGAEMVVQSLIEENVEQIFGYPGGSVLDIYDALHAKTEQIKHVLVRHEQAATHMADGYA 64

Query: 61  YISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLL 120
             + KPGV+L+  GPG  + + GI  +  +  P++VI+G+   S I    FQE D V + 
Sbjct: 65  RATGKPGVVLVCSGPGATNTITGIATAYMDSIPMIVISGNVPNSLIGNDAFQECDIVGVS 124

Query: 121 SPFLKFTGKLT-PDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNEL 179
            P +K +  +   ++I    +KA      G  G   ID+P D +     L         +
Sbjct: 125 RPVVKHSFLVKRAEDIPETIKKAFYIATTGRPGPVVIDLPKDVMNPLIKLPYEY--PKSI 182

Query: 180 PMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPT 239
            M            +IKK ++ +L+ K   + I  G         I +L  T NLP + T
Sbjct: 183 SMRSYKPTTSGHKGQIKKALKALLEAKKPVLYIGGGAIISGAHESILKLAETLNLPVVST 242

Query: 240 PMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSESI 292
            M  G  P +         ++     + A+  AD++  +G R +         K+   + 
Sbjct: 243 LMGLGAFPGTHKNALGMLGMHGKYEANMAMHNADLIFGVGVRFDDR-TTNNLEKYCPNAK 301

Query: 293 FIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQ 352
            +  D +P ++  N      DL I G     +  +V  L  Q +      +     E I+
Sbjct: 302 IMHIDIDPSSISKN---VKVDLPIVGSAEQVLETMVTLLEEQGAENDTQALASWWDE-IE 357

Query: 353 LNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRR 412
             + R      T   ++   QV  TL  L +    +    G + M  A + +P + PRR 
Sbjct: 358 GWKARDCLAYDTSSERIKPQQVIETLHKLTNGDAYVASDVGQHQM-FAALYYPFNKPRRW 416

Query: 413 LDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMN 472
           +++G   TMG GL   +  K + PE +VV++ GD +   +  E+ TA++  + + I+ +N
Sbjct: 417 INSGGLGTMGFGLPAGMGVKFAMPEEEVVVVTGDGSIQMNIQELSTAMQYDIPVKIINLN 476

Query: 473 NS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQL 528
           N   G+    +DI  +G    + +S    +  + +  G     + T  +L    ++A+ +
Sbjct: 477 NRFLGMVKQWQDIIYQGRHSNSYMSSVPDFAAIAEAYGHVGIRIETPDQLESELKRALDM 536

Query: 529 SRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
              K     +++ ++  E     QI     +K  L
Sbjct: 537 ---KDRLVFVDINVDETEHVYPMQIKGEGMDKMWL 568
>ref|ZP_01323079.1| hypothetical protein BpseP_03003157 [Burkholderia pseudomallei
           Pasteur]
 ref|ZP_01329678.1| hypothetical protein BpseS_03002231 [Burkholderia pseudomallei S13]
 ref|ZP_01334698.1| hypothetical protein Bpse4_03002771 [Burkholderia pseudomallei
           406e]
          Length = 560

 Score =  879 bits (2273), Expect = 0.0,   Method: Composition-based stats.
 Identities = 124/568 (21%), Positives = 228/568 (40%), Gaps = 30/568 (5%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGYISDKPGV 68
            + L    ++ ++G  G  ++ + D +   + I+ +  R+EQAA +AA AY   + K GV
Sbjct: 1   MKALADENVEFIWGYPGGSVLYIYDELYKQDKIQHVLVRHEQAAVHAADAYSRSTGKVGV 60

Query: 69  LLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTG 128
            L+  GPG+ +A+ GI  +  +  PL+VI+G    + I +  FQE D V +  P +K   
Sbjct: 61  CLVTSGPGVTNAVTGIATAYMDSIPLVVISGQVPTAAIGQDAFQECDTVGITRPCVKHNF 120

Query: 129 KLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNI 187
            +     +    +KA      G  G   ID+P D  +     E        + +     +
Sbjct: 121 LVKDVRELAQTVKKAFYIARTGRPGPVLIDIPKDISKTPCEYE----PVKNVSLRSYNPV 176

Query: 188 CGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMAKGIVP 247
                 +I+K V L+L  K   I    G      S E+ +  +    P   T M  G   
Sbjct: 177 TKGHSGQIRKAVSLLLSAKRPYIYTGGGIILADASRELNQFADLLGYPVTNTLMGLGGYR 236

Query: 248 DSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SIFIQFDSN 299
            S         ++ +   + A++  D+++ +GAR +  +  G    + S     I  D +
Sbjct: 237 SSDRKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRV-IGDPAHFASRPRKIIHIDID 295

Query: 300 PETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLL 359
           P ++         D+ I GD+   +  L+E+L   +       + Q  +E I+  +    
Sbjct: 296 PSSISKR---VKVDIPIVGDVKEVLKELIEQLQTAEHGPDADALAQWWKE-IEGWRGTDC 351

Query: 360 RKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNA 419
            K       +    V   L  L D    +    G + M  A+  +  + PRR +++G   
Sbjct: 352 LKYDRASEIIKPQYVVEKLWELTDGNAFVCSDVGQHQMWAAQF-YRFNKPRRWINSGGLG 410

Query: 420 TMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS--GIY 477
           TMG GL  A+  K +HP+ DVV I G+ +      E+ T  +    + I+ +NN   G+ 
Sbjct: 411 TMGFGLPAAMGVKMAHPDDDVVCITGEGSIQMCIQELSTCKQYDTPVKIISLNNRYLGMV 470

Query: 478 HGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRET 535
              + IE       + +     +  + +  G     +   +++    ++A+ L   K  T
Sbjct: 471 RQWQQIEYSKRYSHSYMDALPDFVKLAQAYGHIGMRIEKSADVEPALKEALSL---KDRT 527

Query: 536 SVINVIIEPGEQ---KQIAFAWQNKPRL 560
             ++   +P E       A     +  L
Sbjct: 528 VFLDFQTDPTENVWPMVQAGKGITEMLL 555
>ref|YP_001899794.1| acetolactate synthase, large subunit, biosynthetic type [Ralstonia
           pickettii 12J]
 gb|ACD27362.1| acetolactate synthase, large subunit, biosynthetic type [Ralstonia
           pickettii 12J]
          Length = 585

 Score =  879 bits (2272), Expect = 0.0,   Method: Composition-based stats.
 Identities = 120/559 (21%), Positives = 231/559 (41%), Gaps = 27/559 (4%)

Query: 3   TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGY 61
                     L   G++ V+G  G  ++ + D     N I+ I  R+EQAA +AA  Y  
Sbjct: 19  MMGADILVNALAAEGVEFVWGYPGGAVLYIYDAFYKQNKIEHILVRHEQAAVHAADGYAR 78

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
            + K GV L+  GPG+ +A+ GI  +  +  P+++I G+     I +  FQE D V +  
Sbjct: 79  ATGKVGVALVTSGPGVTNAVTGIATAYLDSIPMVIITGNVPTHAIGQDAFQECDTVGITR 138

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
           P +K    +    N+    +KA      G  G   +D+P D        E        + 
Sbjct: 139 PIVKHNFLVKDVRNLASTIKKAFYIAATGRPGPVVVDIPKDVSRELCKYEY----PKTIE 194

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
           M     +      +I+K V L+LQ +   I    G    + S E+R+L      P   T 
Sbjct: 195 MRSYSPVNKGHSGQIRKAVSLLLQAERPYIYSGGGVVLAEASEELRQLAALTGYPVTNTL 254

Query: 241 MAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKW-NSESI 292
           M  G  P +S        ++ +   + A++  D+++ +GAR +  +  G+   + +    
Sbjct: 255 MGLGAFPGTSKQFVGMLGMHGTYEANMAMQNCDVLIAIGARFDDRV-IGSPAHFTSQPRK 313

Query: 293 FIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQ 352
            I  D +P ++         D+ I G++   +  ++ ++   ++    + + +   E+I+
Sbjct: 314 IIHIDIDPSSISKR---VKVDIPIVGNVKDVLQEMIAQIQSGEAKPNKTALAKWW-EQIE 369

Query: 353 LNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRR 412
             ++    K       +    V   +  L +    I    G + M  A+  +  + PRR 
Sbjct: 370 QWRSVDCLKYDRTSEIIKPQYVVEKIWELTNGDAFICSDVGQHQMWAAQF-YKFNEPRRW 428

Query: 413 LDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMN 472
           +++G   TMG+GL YA+  K + P+ +VV I G+ +      E+ T ++    + I  +N
Sbjct: 429 INSGGLGTMGVGLPYAMGIKKAFPDKEVVTITGEGSIQMCIQELSTCLQYDTPVKICSLN 488

Query: 473 NS--GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQL 528
           N   G+    ++IE       + +     +  + +  G     +   S++    ++A   
Sbjct: 489 NGYLGMVRQWQEIEYDNRYSHSYMQALPDFVKLAESYGHVGMRIEKTSDVEPALREAF-- 546

Query: 529 SRTKRETSVINVIIEPGEQ 547
            R K  T  ++   +P E 
Sbjct: 547 -RLKDRTVFLDFQTDPTEN 564
>ref|ZP_01706659.1| acetolactate synthase, large subunit, biosynthetic type [Shewanella
           putrefaciens 200]
 gb|EAY53043.1| acetolactate synthase, large subunit, biosynthetic type [Shewanella
           putrefaciens 200]
          Length = 572

 Score =  879 bits (2272), Expect = 0.0,   Method: Composition-based stats.
 Identities = 121/581 (20%), Positives = 231/581 (39%), Gaps = 33/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +      + L   G+  VFG  G  ++ + D +    GI+ I  R+EQAA + A  
Sbjct: 1   MEMLSGASMIVRSLIDEGVKHVFGYPGGSVLDIYDALHVIPGIEHILVRHEQAAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + K GV+L+  GPG  +A+ GI  +  +  PL+V++G    + I    FQE D + 
Sbjct: 61  YARATGKVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQVPSNLIGNDAFQECDMIG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +  P  I  I +KA      G  G   +D+P D +      E       
Sbjct: 121 ISRPVVKHSFLVQDPKQIPEIIKKAFYIASTGRPGPVVVDLPKDCLNPALLHEYLY--PE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +I++ +Q +L  K   + +  G        +I +L    N+P +
Sbjct: 179 SVKMRSYNPTTSGHKGQIRRGLQALLTAKKPVLYVGGGAIISGCDKQILQLAEKLNIPVI 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            T M  G  P +         ++     +  +   D++  +G R +         K+   
Sbjct: 239 STLMGLGAFPSTHKNSLGMLGMHGRYEANMTMHHCDLIFGIGVRFDDR-TTNNVEKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +   D+ I G     + +++  L   +       +     + 
Sbjct: 298 ATILHIDIDPSSISK---TVRVDIPIVGSADSVLDSMLTLLDESNERNDNDAIATWWND- 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  ++R          ++   QV  TL  L      I    G + M  A + +P D PR
Sbjct: 354 IEQWRSRNSLAYDKNTDRIKPQQVIETLYKLTHGDAYIASDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  A+  K + P+  VV + GD +   +  E+ TA++    + I+ 
Sbjct: 413 RWINSGGLGTMGFGLPAAMGVKLAMPDETVVCVTGDGSIQMNIQELSTALQYDTPVKIIN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++  +EL     +A+
Sbjct: 473 LNNRFLGMVKQWQDMIYSGRHSHSYMDSVPNFAKIAEAYGHVGMTISDPAELESKMAEAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
            +   K     I+++++  E           +   W +K  
Sbjct: 533 AM---KDRLVFIDIMVDETEHVYPMLIRGGAMNEMWLSKTE 570
>ref|YP_851278.1| acetolactate synthase 3 catalytic subunit [Escherichia coli APEC
           O1]
 gb|ABE05595.1| acetolactate synthase isozyme III large subunit [Escherichia coli
           UTI89]
 gb|ABI99563.1| acetolactate synthase isozyme III large subunit [Escherichia coli
           APEC O1]
          Length = 604

 Score =  879 bits (2272), Expect = 0.0,   Method: Composition-based stats.
 Identities = 125/577 (21%), Positives = 243/577 (42%), Gaps = 26/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQAA + A  
Sbjct: 31  MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQAAVHMADG 90

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
               + + GV+L+  GPG  +A+ GI  +  +  PL+V++G  + S I    FQE D V 
Sbjct: 91  LARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVG 150

Query: 119 LLSPFLKFTGKLT-PDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   +D+P D +     L        
Sbjct: 151 ISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDLPKDILNPANKL--PYVWPE 208

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +IK+ +Q ++  K   + +  G        +++  V   NLP +
Sbjct: 209 SVSMRSYNPTTSGHKGQIKRALQTLVAAKKPVVYVGGGAITAGCHLQLKEAVEVLNLPVV 268

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   +  +  AD++  +G R +         K+   
Sbjct: 269 SSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVIFAVGVRFDDR-TTNNLAKYCPN 327

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +  ++E L+++ +      ++    ++
Sbjct: 328 ATVLHIDIDPTSISK---TVTADIPIVGDARQVLEQMLELLSQESAHQPLDEIRDWW-QQ 383

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R   K  T   ++    V  TL  L      +    G + M  A + +P D PR
Sbjct: 384 IEQWRARQCLKYDTHSEKIKPQAVIETLWRLTHGDAYVTSDVGQHQM-FAALYYPFDKPR 442

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + PE  VV + GD +   +  E+ TA++ +L +++V 
Sbjct: 443 RWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVVN 502

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++   EL     +A+
Sbjct: 503 LNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLAEAYGHVGIQISHPQELESKLSEAL 562

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
           +  R       ++V ++  E     QI     ++  L
Sbjct: 563 EQVRN-NRLVFVDVTVDGSEHVYPMQIRGGGMDEMWL 598
>ref|YP_001183658.1| acetolactate synthase 3 catalytic subunit [Shewanella putrefaciens
           CN-32]
 gb|ABP75859.1| acetolactate synthase, large subunit, biosynthetic type [Shewanella
           putrefaciens CN-32]
          Length = 572

 Score =  879 bits (2272), Expect = 0.0,   Method: Composition-based stats.
 Identities = 120/581 (20%), Positives = 231/581 (39%), Gaps = 33/581 (5%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +      + L   G+  VFG  G  ++ + D +    GI+ I  R+EQAA + A  
Sbjct: 1   MEMLSGASMIVRSLIDEGVKHVFGYPGGSVLDIYDALHVIPGIEHILVRHEQAAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
           Y   + K GV+L+  GPG  +A+ GI  +  +  PL+V++G    + I    FQE D + 
Sbjct: 61  YARATGKVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQVPSNLIGNDAFQECDMIG 120

Query: 119 LLSPFLKFTGKL-TPDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +  P  I  I +KA      G  G   +D+P D +      E       
Sbjct: 121 ISRPVVKHSFLVQDPKQIPEIIKKAFYIASTGRPGPVVVDLPKDCLNPALLHEYLY--PE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +I++ +Q +L  K   + +  G        +I +L    N+P +
Sbjct: 179 SVKMRSYNPTTSGHKGQIRRGLQALLTAKKPVLYVGGGAIISGCDKQILQLAEKLNIPVI 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            T M  G  P +         ++     +  +   D++  +G R +         K+   
Sbjct: 239 STLMGLGAFPSTHKNSLGMLGMHGRYEANMTMHHCDLIFGIGVRFDDR-TTNNVEKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +   D+ I G     + +++  L   +       +     + 
Sbjct: 298 ATILHIDIDPSSISK---TVRVDIPIVGSADSVLDSMLTLLDESNERNDNDAIATWWND- 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  ++R          ++   QV  TL  L      +    G + M  A + +P D PR
Sbjct: 354 IEQWRSRNSLAYDKNTDRIKPQQVIETLYKLTHGDAYVASDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  A+  K + P+  VV + GD +   +  E+ TA++    + I+ 
Sbjct: 413 RWINSGGLGTMGFGLPAAMGVKLAMPDETVVCVTGDGSIQMNIQELSTALQYDTPVKIIN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++  +EL     +A+
Sbjct: 473 LNNRFLGMVKQWQDMIYSGRHSHSYMDSVPNFAKIAEAYGHVGMTISDPAELESKMAEAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ--------KQIAFAWQNKPR 559
            +   K     I+++++  E           +   W +K  
Sbjct: 533 AM---KDRLVFIDIMVDETEHVYPMLIRGGAMNEMWLSKTE 570
>gb|ABU63575.1| AHAS catalytic subunit [Klebsiella pneumoniae]
          Length = 574

 Score =  879 bits (2272), Expect = 0.0,   Method: Composition-based stats.
 Identities = 123/577 (21%), Positives = 246/577 (42%), Gaps = 26/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVANG-IKFIPCRNEQAASYAASA 58
           M   +  +   Q L   G+  VFG  G  ++ + D +   G I  +  R+EQAA + A  
Sbjct: 1   MEMLSGAEMVVQSLVDQGVKQVFGYPGGAVLDIYDALHTLGGIDHVLVRHEQAAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
               + + GV+L+  GPG  +A+ GI  +  +  PL++++G  + S I    FQE D V 
Sbjct: 61  LARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVILSGQVATSLIGYDAFQECDMVG 120

Query: 119 LLSPFLKFTGKLT-PDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   +D+P D +   K L        
Sbjct: 121 ISRPVVKHSFLVKQTEDIPGVLKKAFWLAASGRPGPVVVDLPKDILNPAKKL--PYAWPE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +IK+ +Q ++      + +  G        ++R LV    LP  
Sbjct: 179 AVSMRSYNPTTSGHKGQIKRALQTLVAASKPVVYVGGGAINAHCEPQLRELVEKLKLPVA 238

Query: 238 PTPMAKGIVPDSSP-------LNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P + P       ++ +   +  +  +D++  +G R +         K+   
Sbjct: 239 SSLMGLGAFPATHPQALGMLGMHGTYEANMTMHHSDVIFAVGVRFDDR-TTNNLAKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD  L +  ++E L ++++      ++    ++
Sbjct: 298 ATVLHIDIDPTSISK---TVPADVPIVGDARLVLEQMLELLDQEETQQPLDDIRDWW-QQ 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R   +   +  ++    V  T+  L      +    G + M  A + +P D PR
Sbjct: 354 IEQWRARHCLRYDDQSDKIKPQAVIETIWRLTQGDAYVTSDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + P+  VV + GD +   +  E+ TA++ +L ++++ 
Sbjct: 413 RWINSGGLGTMGFGLPAALGVKMALPDEMVVCVTGDGSIQMNIQELSTALQYELPVLVLN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++   EL     +A+
Sbjct: 473 LNNRYLGMVKQWQDMLYSGRHSQSYMESLPDFVRLAEAYGHVGIRISEPQELESKLAEAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
           +  R +R    ++V ++  E     QI     ++  L
Sbjct: 533 EQVR-QRRLVFVDVTVDGSEHVYPMQIRGGGMDEMWL 568
>ref|ZP_00440969.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Burkholderia mallei GB8 horse 4]
 ref|ZP_00930675.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Burkholderia mallei FMH]
 ref|ZP_00934098.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Burkholderia mallei JHU]
 ref|ZP_01338679.1| hypothetical protein Bmal2_03003608 [Burkholderia mallei
           2002721280]
 ref|ZP_01344073.1| hypothetical protein Bmal10_03003117 [Burkholderia mallei 10399]
          Length = 560

 Score =  878 bits (2271), Expect = 0.0,   Method: Composition-based stats.
 Identities = 124/568 (21%), Positives = 228/568 (40%), Gaps = 30/568 (5%)

Query: 10  AQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGYISDKPGV 68
            + L    ++ ++G  G  ++ + D +   + I+ +  R+EQAA +AA AY   + K GV
Sbjct: 1   MKALADENVEFIWGYPGGSVLYIYDELYKQDKIQHVLVRHEQAAVHAADAYSRSTGKVGV 60

Query: 69  LLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTG 128
            L+  GPG+ +A+ GI  +  +  PL+VI+G    + I +  FQE D V +  P +K   
Sbjct: 61  CLVTSGPGVTNAVTGIATAYMDSIPLVVISGQVPTAAIGQDAFQECDTVGITRPCVKHNF 120

Query: 129 KLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELPMILTPNI 187
            +     +    +KA      G  G   ID+P D  +     E        + +     +
Sbjct: 121 LVKDVRELAQTVKKAFYIARTGRPGPVLIDIPKDISKTPCEYE----PVKNVSLRSYNPV 176

Query: 188 CGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTPMAKGIVP 247
                 +I+K V L+L  K   I    G      S E+ +  +    P   T M  G   
Sbjct: 177 TKGHSGQIRKAVSLLLSAKRPYIYTGGGIILADASRELNQFADLLGYPVTNTLMGLGGYR 236

Query: 248 DSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SIFIQFDSN 299
            S         ++ +   + A++  D+++ +GAR +  +  G    + S     I  D +
Sbjct: 237 SSDRKFLGMLGMHGTYEANMAMQHCDVLIAIGARFDDRV-IGDPAHFASRPRKIIHIDID 295

Query: 300 PETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQLNQTRLL 359
           P ++         D+ I GD+   +  L+E+L   +       + Q  +E I+  +    
Sbjct: 296 PSSISKR---VKVDIPIVGDVKEVLKELIEQLQTAEHGSDADALAQWWKE-IEGWRGTDC 351

Query: 360 RKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNA 419
            K       +    V   L  L D    +    G + M  A+  +  + PRR +++G   
Sbjct: 352 LKYDRASEIIKPQYVVEKLWELTDGNAFVCSDVGQHQMWAAQF-YRFNKPRRWINSGGLG 410

Query: 420 TMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMNNS--GIY 477
           TMG GL  A+  K +HP+ DVV I G+ +      E+ T  +    + I+ +NN   G+ 
Sbjct: 411 TMGFGLPAAMGVKMAHPDDDVVCITGEGSIQMCIQELSTCKQYDTPVKIISLNNRYLGMV 470

Query: 478 HGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQLSRTKRET 535
              + IE       + +     +  + +  G     +   +++    ++A+ L   K  T
Sbjct: 471 RQWQQIEYSKRYSHSYMDALPDFVKLAQAYGHIGMRIEKSADVEPALKEALSL---KDRT 527

Query: 536 SVINVIIEPGEQ---KQIAFAWQNKPRL 560
             ++   +P E       A     +  L
Sbjct: 528 VFLDFQTDPTENVWPMVQAGKGITEMLL 555
>ref|ZP_00943336.1| Acetolactate synthase large subunit [Ralstonia solanacearum UW551]
 gb|EAP74158.1| Acetolactate synthase large subunit [Ralstonia solanacearum UW551]
          Length = 585

 Score =  878 bits (2271), Expect = 0.0,   Method: Composition-based stats.
 Identities = 120/559 (21%), Positives = 230/559 (41%), Gaps = 27/559 (4%)

Query: 3   TTATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMV-ANGIKFIPCRNEQAASYAASAYGY 61
                     L   G++ V+G  G  ++ + D     N I+ I  R+EQAA +AA  Y  
Sbjct: 19  MMGADILVNALAAEGVEFVWGYPGGAVLYIYDAFYKQNKIEHILVRHEQAAVHAADGYAR 78

Query: 62  ISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLS 121
            + K GV L+  GPG+ +A+ GI  +  +  P+++I G+     I +  FQE D V +  
Sbjct: 79  ATGKVGVALVTSGPGVTNAVTGIATAYLDSIPMVIITGNVPTHAIGQDAFQECDTVGITR 138

Query: 122 PFLKFTGKLTP-DNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGNELP 180
           P +K    +    N+    +KA      G  G   +D+P D        E        + 
Sbjct: 139 PIVKHNFLVKDVRNLASTIKKAFYIASTGRPGPVVVDIPKDVSRDLCKYEY----PKTIE 194

Query: 181 MILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFLPTP 240
           M     +      +I+K V L+LQ +   I    G      S E+R+L      P   T 
Sbjct: 195 MRSYNPVNKGHSGQIRKAVSLLLQAERPYIYTGGGVVLANASDELRQLAALTGYPVTNTL 254

Query: 241 MAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE-SI 292
           M  G  P +S        ++ +   + A++  D+++ +GAR +  +  G+   + S+   
Sbjct: 255 MGLGSFPGTSKQFVGMLGMHGTYEANMAMQHCDVLIAVGARFDDRV-IGSPAHFASQPRK 313

Query: 293 FIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREKIQ 352
            I  D +P ++         D+ I G++   +  ++ ++   ++      + +   E+I+
Sbjct: 314 IIHIDIDPSSISKR---VKVDIPIVGNVKDVLQEMIAQIQAGEAKPNKVALAKWW-EQIE 369

Query: 353 LNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRR 412
             ++    K       +    V   +  L      I    G + M  A+  +  + PRR 
Sbjct: 370 QWRSVDCLKYDRTSEIIKPQYVVEKIWELTAGDAFICSDVGQHQMWAAQF-YKFNEPRRW 428

Query: 413 LDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVVMN 472
           +++G   TMG+GL YA+  K + P+ +VV I G+ +      E+ T ++    + I  +N
Sbjct: 429 INSGGLGTMGVGLPYAMGVKKAFPDKEVVTITGEGSIQMCIQELSTCLQYNTPVKIAALN 488

Query: 473 NS--GIYHGEKDIEG--DLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAVQL 528
           N   G+    ++IE       + +     +  + +  G     +   +++    ++A +L
Sbjct: 489 NRYLGMVRQWQEIEYDNRYSHSYMEALPDFVKLAEAYGHVGMRIEKTADVEPALREAFKL 548

Query: 529 SRTKRETSVINVIIEPGEQ 547
              K  T  ++   +P E 
Sbjct: 549 ---KDRTVFMDFQTDPTEN 564
>ref|ZP_00923850.1| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate
           synthase, pyruvate dehydrogenase (cytochrome),
           glyoxylate carboligase, phosphonopyruvate decarboxylase]
           [Escherichia coli 101-1]
          Length = 574

 Score =  878 bits (2271), Expect = 0.0,   Method: Composition-based stats.
 Identities = 125/577 (21%), Positives = 244/577 (42%), Gaps = 26/577 (4%)

Query: 1   MTT-TATQHFAQLLQKYGIDTVFGIVGIPIVQLADTMVA-NGIKFIPCRNEQAASYAASA 58
           M   +  +   + L   G+  VFG  G  ++ + D +    GI  +  R+EQAA + A  
Sbjct: 1   MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQAAVHMADG 60

Query: 59  YGYISDKPGVLLIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVS 118
               + + GV+L+  GPG  +A+ GI  +  +  PL+V++G  + S I    FQE D V 
Sbjct: 61  LARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVG 120

Query: 119 LLSPFLKFTGKLT-PDNIDMITQKALNYCIQGTAGVSYIDVPADFIEYEKPLEGNDRTGN 177
           +  P +K +  +   ++I  + +KA      G  G   +D+P D +     L        
Sbjct: 121 ISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDLPKDILNPANKL--PYVWPE 178

Query: 178 ELPMILTPNICGPDPSKIKKVVQLILQHKNKNILIVIGKGAVKNSHEIRRLVNTFNLPFL 237
            + M            +IK+ +Q ++  K   + +  G        +++ +V   NLP +
Sbjct: 179 SVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAITAGCHQQLKEMVEALNLPVV 238

Query: 238 PTPMAKGIVPDSS-------PLNVSSARSQALKIADIVLVLGARLNWILHFGTSPKWNSE 290
            + M  G  P +         ++ +   +  +  AD++  +G R +         K+   
Sbjct: 239 SSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVIFAVGVRFDDR-TTNNLAKYCPN 297

Query: 291 SIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEELTRQDSCWKYSGVKQEIREK 350
           +  +  D +P ++     +  AD+ I GD    +  ++E L+++ +      ++    ++
Sbjct: 298 ATVLHIDIDPTSISK---TVTADIPIVGDARQVLEQMLELLSQESAHQPLDEIRDWW-QQ 353

Query: 351 IQLNQTRLLRKEKTRGAQLNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPR 410
           I+  + R   K  T   ++    V  TL  L      +    G + M  A + +P D PR
Sbjct: 354 IEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGDAYVTSDVGQHQM-FAALYYPFDKPR 412

Query: 411 RRLDAGTNATMGIGLGYALACKASHPELDVVLIQGDSAFGFSAMEIETAVRCQLALVIVV 470
           R +++G   TMG GL  AL  K + PE  VV + GD +   +  E+ TA++ +L +++V 
Sbjct: 413 RWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVVN 472

Query: 471 MNNS--GIYHGEKDI--EGDLPPTALSKNCRYDLVGKGLGANDFFVNTISELSRCFQQAV 526
           +NN   G+    +D+   G    + +     +  + +  G     ++   EL     +A+
Sbjct: 473 LNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLAEAYGHVGIQISHPHELESKLSEAL 532

Query: 527 QLSRTKRETSVINVIIEPGEQ---KQIAFAWQNKPRL 560
           +  R       ++V ++  E     QI     ++  L
Sbjct: 533 EQVRN-NRLVFVDVTVDGSEHVYPMQIRGGGMDEMWL 568
  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF excluding environmental samples
  from WGS projects
    Posted date:  May 23, 2008  5:56 PM
  Number of letters in database: 883,778,997
  Number of sequences in database:  2,617,685
  
  Database: /host/Blast/data/nr_perl/nr.01
    Posted date:  May 23, 2008  5:54 PM
  Number of letters in database: 976,759,346
  Number of sequences in database:  2,761,413
  
  Database: /host/Blast/data/nr_perl/nr.02
    Posted date:  May 23, 2008  5:48 PM
  Number of letters in database: 374,670,760
  Number of sequences in database:  1,165,270
  
  Database: /host/Blast/data/nr_perl/nr.03
    Posted date:  Apr 28, 2009  5:40 PM
  Number of letters in database: 114,943,120
  Number of sequences in database:  354,819
  
Lambda     K      H
   0.315    0.199    0.691 

Lambda     K      H
   0.267   0.0610    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,327,832,726
Number of Sequences: 6899187
Number of extensions: 768565835
Number of successful extensions: 1877600
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 12793
Number of HSP's successfully gapped in prelim test: 4163
Number of HSP's that attempted gapping in prelim test: 1773645
Number of HSP's gapped (non-prelim): 23056
length of query: 560
length of database: 2,350,152,223
effective HSP length: 140
effective length of query: 420
effective length of database: 1,384,266,043
effective search space: 581391738060
effective search space used: 581391738060
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 83 (36.0 bits)