BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= YGL037C__[Saccharomyces_cerevisiae]
(216 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_011478.1| Nicotinamidase that converts nicotinamide ... 424 e-117
ref|XP_444840.1| hypothetical protein CAGL0A01716g [Candida... 258 3e-67
ref|XP_456073.1| unnamed protein product [Kluyveromyces lac... 211 2e-53
ref|NP_986013.1| AFR466Cp [Ashbya gossypii ATCC 10895] >gi|... 192 2e-47
ref|XP_001644836.1| hypothetical protein Kpol_1041p36 [Vand... 153 8e-36
ref|XP_001523752.1| hypothetical protein LELG_05168 [Lodder... 148 3e-34
ref|XP_500320.1| hypothetical protein [Yarrowia lipolytica]... 146 8e-34
ref|XP_888958.1| hypothetical protein CaJ7.0402 [Candida al... 145 1e-33
ref|XP_458267.1| hypothetical protein DEHA0C14564g [Debaryo... 144 5e-33
ref|XP_001482603.1| hypothetical protein PGUG_05623 [Pichia... 139 1e-31
ref|ZP_02061772.1| pyrazinamidase/nicotinamidase (PZAase)(N... 132 1e-29
ref|XP_001874048.1| predicted protein [Laccaria bicolor S23... 132 2e-29
ref|XP_364131.1| hypothetical protein MGG_08976 [Magnaporth... 132 2e-29
ref|XP_001385959.2| NAD(+) salvage pathway gene [Pichia sti... 129 1e-28
ref|ZP_02965199.1| isochorismatase hydrolase [bacterium Ell... 128 3e-28
ref|XP_001245038.1| hypothetical protein CIMG_04479 [Coccid... 127 6e-28
ref|ZP_01853806.1| pyrazinamidase/nicotinamidase [Planctomy... 126 8e-28
ref|XP_001829253.1| hypothetical protein CC1G_06590 [Coprin... 126 1e-27
ref|ZP_01955355.1| pyrazinamidase/nicotinamidase [Vibrio ch... 125 2e-27
ref|XP_001593095.1| hypothetical protein SS1G_06017 [Sclero... 124 4e-27
ref|ZP_03823780.1| nicotinamidase-like amidase [Acinetobact... 124 5e-27
ref|ZP_01675333.1| pyrazinamidase/nicotinamidase [Vibrio ch... 123 1e-26
ref|NP_233099.1| pyrazinamidase/nicotinamidase [Vibrio chol... 122 1e-26
gb|EDN16169.1| pyrazinamidase/nicotinamidase [Vibrio choler... 122 1e-26
ref|YP_342331.1| Nicotinamidase [Nitrosococcus oceani ATCC ... 122 2e-26
ref|XP_001559960.1| hypothetical protein BC1G_01519 [Botryo... 122 2e-26
ref|XP_001417004.1| predicted protein [Ostreococcus lucimar... 122 2e-26
ref|XP_001218134.1| conserved hypothetical protein [Aspergi... 121 4e-26
ref|ZP_01908379.1| nicotinamidase/pyrazinamidase [Plesiocys... 120 6e-26
ref|YP_001817930.1| Nicotinamidase [Opitutus terrae PB90-1]... 119 1e-25
ref|ZP_03965982.1| nicotinamidase [Sphingobacterium spiriti... 119 1e-25
ref|ZP_01094319.1| pyrazinamidase/nicotinamidase [Blastopir... 119 2e-25
ref|YP_001899019.1| Nicotinamidase [Ralstonia pickettii 12J... 118 3e-25
ref|ZP_01756653.1| pyrazinamidase/nicotinamidase [Roseobact... 118 4e-25
ref|NP_142913.1| pyrazinamidase/nicotinamidase [Pyrococcus ... 117 5e-25
ref|ZP_01745842.1| pyrazinamidase/nicotinamidase [Sagittula... 117 6e-25
ref|YP_001006490.1| nicotinamidase/pyrazinamidase [Yersinia... 117 6e-25
ref|YP_001400957.1| pyrazinamidase/nicotinamidase [Yersinia... 116 9e-25
ref|XP_001912686.1| unnamed protein product [Podospora anse... 116 9e-25
ref|YP_070603.1| nicotinamidase/pyrazinamidase [Yersinia ps... 116 1e-24
ref|NP_405705.1| nicotinamidase/pyrazinamidase [Yersinia pe... 116 1e-24
ref|ZP_03850627.1| Nicotinamidase [Chryseobacterium gleum A... 116 1e-24
ref|ZP_00710421.1| COG1335: Amidases related to nicotinamid... 116 1e-24
ref|ZP_02152324.1| pyrazinamidase/nicotinamidase [Oceanibul... 116 1e-24
ref|YP_222148.1| PncA, pyrazinamidase/nicotinamidase [Bruce... 115 1e-24
ref|NP_105653.1| pyrazinamidase/nicotinamidase [Mesorhizobi... 115 2e-24
ref|YP_001743481.1| pyrazinamidase/nicotinamidase [Escheric... 115 2e-24
ref|ZP_02826083.1| pyrazinamidase/nicotinamidase [Escherich... 115 2e-24
gb|AAZ88098.1| conserved hypothetical protein [Shigella son... 115 2e-24
gb|AAG56755.1|AE005399_9 orf, hypothetical protein [Escheri... 115 3e-24
ref|NP_288202.2| nicotinamidase/pyrazinamidase [Escherichia... 115 3e-24
ref|AP_002387.1| nicotinamidase/pyrazinamidase [Escherichia... 115 3e-24
ref|YP_688945.1| nicotinamidase/pyrazinamidase [Shigella fl... 115 3e-24
gb|AAN43052.1| orf, conserved hypothetical protein [Shigell... 115 3e-24
ref|NP_771189.1| pyrazinamidase/nicotinamidase [Bradyrhizob... 115 3e-24
ref|NP_578834.1| pyrazinamidase/nicotinamidase pxnc [Pyroco... 115 3e-24
ref|ZP_00924703.1| COG1335: Amidases related to nicotinamid... 114 3e-24
ref|ZP_00921076.1| COG1335: Amidases related to nicotinamid... 114 3e-24
ref|YP_001463067.1| pyrazinamidase/nicotinamidase [Escheric... 114 3e-24
ref|ZP_00714471.1| COG1335: Amidases related to nicotinamid... 114 4e-24
ref|YP_407774.2| nicotinamidase/pyrazinamidase [Shigella bo... 114 4e-24
ref|XP_749509.1| isochorismatase family hydrolase [Aspergi... 114 4e-24
gb|EDP54034.1| isochorismatase family hydrolase, putative ... 114 5e-24
ref|NP_539463.1| PYRAZINAMIDASE / NICOTINAMIDASE [Brucella ... 114 5e-24
ref|XP_567125.1| nicotinamidase [Cryptococcus neoformans va... 114 5e-24
ref|ZP_01062411.1| bifunctional pyrazinamidase/nicotinamida... 114 6e-24
ref|ZP_01127503.1| Nicotinamidase [Nitrococcus mobilis Nb-2... 114 6e-24
ref|YP_295620.1| Nicotinamidase [Ralstonia eutropha JMP134]... 114 7e-24
ref|YP_184063.1| probable nicotinamidase [Thermococcus koda... 114 7e-24
ref|ZP_02189181.1| isochorismatase hydrolase [alpha proteob... 114 7e-24
ref|YP_048046.1| bifunctional protein [Includes: pyrazinami... 113 8e-24
ref|ZP_00720836.1| COG1335: Amidases related to nicotinamid... 113 8e-24
ref|XP_389372.1| hypothetical protein FG09196.1 [Gibberella... 113 8e-24
ref|ZP_00954335.1| pyrazinamidase/nicotinamidase [Sulfitoba... 113 9e-24
ref|ZP_00628264.1| Nicotinamidase [Paracoccus denitrificans... 113 1e-23
ref|ZP_02010336.1| Nicotinamidase [Ralstonia pickettii 12D]... 113 1e-23
ref|ZP_01035501.1| pyrazinamidase/nicotinamidase [Roseovari... 113 1e-23
ref|ZP_02742886.1| nicotinamidase/pyrazinamidase [Escherich... 112 1e-23
ref|YP_001259350.1| pyrazinamidase/nicotinamidase [Brucella... 112 1e-23
ref|YP_403134.2| nicotinamidase/pyrazinamidase [Shigella dy... 112 1e-23
gb|ABB61643.1| conserved hypothetical protein [Shigella dys... 112 1e-23
ref|ZP_02146752.1| Nicotinamidase [Phaeobacter gallaeciensi... 112 1e-23
ref|ZP_01055578.1| pyrazinamidase/nicotinamidase [Roseobact... 112 2e-23
ref|YP_669620.1| nicotinamidase/pyrazinamidase [Escherichia... 112 2e-23
ref|ZP_00725208.1| COG1335: Amidases related to nicotinamid... 112 2e-23
ref|ZP_00979781.1| COG1335: Amidases related to nicotinamid... 112 2e-23
ref|YP_002756145.1| isochorismatase family protein [Acidoba... 112 2e-23
ref|ZP_02813180.1| nicotinamidase/pyrazinamidase [Escherich... 112 2e-23
ref|XP_001636465.1| predicted protein [Nematostella vectens... 112 2e-23
ref|XP_001818423.1| hypothetical protein [Aspergillus oryza... 112 2e-23
ref|YP_001857264.1| Nicotinamidase [Burkholderia phymatum S... 112 2e-23
ref|XP_001272808.1| isochorismatase family hydrolase, puta... 112 2e-23
ref|ZP_00999691.1| pyrazinamidase/nicotinamidase [Oceanicol... 112 2e-23
ref|YP_190619.1| Pyrazinamidase/nicotinamidase [Gluconobact... 112 3e-23
ref|ZP_02151488.1| pyrazinamidase/nicotinamidase [Phaeobact... 111 3e-23
ref|YP_001821378.1| Nicotinamidase [Opitutus terrae PB90-1]... 111 3e-23
ref|YP_001628120.1| Nicotinamidase [Brucella suis ATCC 2344... 111 3e-23
ref|XP_629052.1| nicotinamidase [Dictyostelium discoideum A... 111 4e-23
ref|ZP_02295815.1| Nicotinamidase [Rhizobium leguminosarum ... 111 4e-23
ref|ZP_00829124.1| COG1335: Amidases related to nicotinamid... 111 4e-23
ref|NP_519881.1| PROBABLE BIFUNCTIONAL PROTEIN: PYRAZINAMID... 111 4e-23
ref|ZP_01717575.1| pyrazinamidase/nicotinamidase [Algoripha... 111 4e-23
ref|YP_001593297.1| Nicotinamidase [Brucella canis ATCC 233... 111 4e-23
ref|YP_001249688.1| bifunctional pyrazinamidase/nicotinamid... 110 5e-23
ref|ZP_01877931.1| Nicotinamidase [Roseovarius sp. TM1035] ... 110 5e-23
ref|YP_002824764.1| pyrazinamidase/nicotinamidase [Rhizobiu... 110 6e-23
ref|NP_126660.1| pyrazinamidase/nicotinamidase [Pyrococcus ... 110 6e-23
ref|NP_698460.1| pyrazinamidase/nicotinamidase [Brucella su... 110 8e-23
ref|ZP_02530352.1| pyrazinamidase/nicotinamidase (pncA) [Bo... 110 8e-23
ref|YP_369444.1| Nicotinamidase [Burkholderia sp. 383] >gi|... 110 8e-23
ref|YP_584002.1| isochorismatase hydrolase [Ralstonia metal... 110 8e-23
ref|ZP_00825895.1| COG1335: Amidases related to nicotinamid... 110 9e-23
ref|ZP_00820544.1| COG1335: Amidases related to nicotinamid... 110 9e-23
ref|YP_125690.1| nicotinamidase/ pyrazinamidase [Legionella... 110 9e-23
ref|XP_964547.1| hypothetical protein NCU00713 [Neurospora ... 110 9e-23
ref|YP_726027.1| Bifunctional Pyrazinamidase/Nicotinamidase... 110 9e-23
ref|ZP_00948880.1| pyrazinamidase/nicotinamidase [Sulfitoba... 110 1e-22
ref|ZP_01443288.1| pyrazinamidase/nicotinamidase [Roseovari... 109 1e-22
ref|YP_001765211.1| Nicotinamidase [Burkholderia cenocepaci... 109 1e-22
ref|YP_835549.1| Nicotinamidase [Burkholderia cenocepacia H... 109 1e-22
ref|YP_001808522.1| Nicotinamidase [Burkholderia ambifaria ... 109 1e-22
ref|XP_001800076.1| hypothetical protein SNOG_09789 [Phaeos... 109 1e-22
ref|YP_742097.1| Nicotinamidase [Alkalilimnicola ehrlichei ... 109 1e-22
ref|YP_001478953.1| Nicotinamidase [Serratia proteamaculans... 109 1e-22
ref|ZP_01015636.1| pyrazinamidase/nicotinamidase [Rhodobact... 109 1e-22
ref|NP_929791.1| nicotinamidase/pyrazinamidase [Photorhabdu... 109 1e-22
ref|YP_001579554.1| Nicotinamidase [Burkholderia multivoran... 109 2e-22
ref|YP_001119675.1| Nicotinamidase [Burkholderia vietnamien... 109 2e-22
ref|YP_001609939.1| pyrazinamidase/nicotinamidase [Bartonel... 109 2e-22
ref|XP_001540638.1| conserved hypothetical protein [Ajellom... 108 2e-22
ref|ZP_02324315.1| Nicotinamidase [Anaeromyxobacter dehalog... 108 2e-22
ref|YP_348618.1| Nicotinamidase [Pseudomonas fluorescens Pf... 108 2e-22
ref|ZP_01902192.1| pyrazinamidase/nicotinamidase [Roseobact... 108 2e-22
ref|ZP_00986621.1| COG1335: Amidases related to nicotinamid... 108 2e-22
gb|ACO60641.1| nicotinamidase/pyrazinamidase domain-contain... 108 2e-22
ref|YP_165367.1| pyrazinamidase/nicotinamidase [Silicibacte... 108 3e-22
ref|ZP_00959572.1| pyrazinamidase/nicotinamidase [Roseovari... 108 3e-22
ref|ZP_02142971.1| pyrazinamidase/nicotinamidase [Roseobact... 108 3e-22
ref|YP_094325.1| bifunctional pyrazinamidase/nicotinamidase... 108 3e-22
ref|ZP_02911546.1| Nicotinamidase [Burkholderia ambifaria M... 108 3e-22
ref|YP_611664.1| Nicotinamidase [Silicibacter sp. TM1040] >... 108 3e-22
ref|YP_989240.1| isochorismatase family protein [Bartonella... 108 3e-22
ref|ZP_00050215.2| COG1335: Amidases related to nicotinamid... 108 3e-22
ref|ZP_02892197.1| Nicotinamidase [Burkholderia ambifaria I... 108 3e-22
ref|ZP_03836463.1| nicotinamidase/pyrazinamidase [Citrobact... 108 3e-22
ref|XP_712137.1| hypothetical protein CaO19.6684 [Candida a... 108 4e-22
ref|YP_122685.1| nicotinamidase/ pyrazinamidase [Legionella... 107 4e-22
ref|YP_001712055.1| bifunctional protein [Includes: pyrazin... 107 4e-22
ref|YP_001708611.1| bifunctional protein [Includes: pyrazin... 107 4e-22
ref|YP_675744.1| isochorismatase hydrolase [Mesorhizobium s... 107 4e-22
ref|YP_773783.1| Nicotinamidase [Burkholderia ambifaria AMM... 107 4e-22
ref|YP_001534681.1| Nicotinamidase [Dinoroseobacter shibae ... 107 5e-22
ref|ZP_02854449.1| Nicotinamidase [Rhizobium leguminosarum ... 107 5e-22
ref|ZP_02362493.1| pyrazinamidase/nicotinamidase [Burkholde... 107 5e-22
ref|ZP_00945621.1| Pyrazinamidase / Nicotinamidase [Ralston... 107 5e-22
ref|YP_032511.1| Pyrazinamidase /nicotinamidase pnca [Barto... 107 5e-22
ref|YP_626011.1| Nicotinamidase [Burkholderia cenocepacia A... 107 6e-22
ref|YP_001927012.1| Nicotinamidase [Methylobacterium populi... 107 6e-22
ref|ZP_02402385.1| pyrazinamidase/nicotinamidase [Burkholde... 107 6e-22
ref|YP_108047.1| putative pyrazinamidase/nicotinamidase [Bu... 107 6e-22
ref|ZP_02175503.1| Nicotinamidase [Anaeromyxobacter sp. K] ... 107 6e-22
ref|YP_033910.1| Pyrazinamidase /nicotinamidase pncA [Barto... 107 6e-22
ref|ZP_01740438.1| Nicotinamidase [Rhodobacterales bacteriu... 107 6e-22
ref|NP_793078.1| pyrazinamidase/nicotinamidase [Pseudomonas... 107 7e-22
ref|YP_995658.1| Nicotinamidase [Verminephrobacter eiseniae... 107 7e-22
gb|EEH92677.1| conserved hypothetical protein [Citrobacter ... 107 7e-22
ref|YP_768860.1| putative pyrazinamidase/nicotinamidase [Rh... 107 7e-22
ref|ZP_01644702.1| Nicotinamidase [Stenotrophomonas maltoph... 107 8e-22
ref|XP_001708441.1| Pyrazinamidase/nicotinamidase [Giardia ... 107 8e-22
ref|ZP_01764334.1| pyrazinamidase/nicotinamidase [Burkholde... 107 8e-22
ref|ZP_02355353.1| pyrazinamidase/nicotinamidase [Burkholde... 107 8e-22
ref|ZP_01154749.1| pyrazinamidase/nicotinamidase [Oceanicol... 106 9e-22
ref|XP_805731.1| alpha/beta-hydrolase, putative [Trypanosom... 106 9e-22
ref|YP_001848274.1| Amidase related to nicotinamidase [Acin... 106 9e-22
ref|YP_103089.1| pyrazinamidase/nicotinamidase [Burkholderi... 106 9e-22
ref|XP_001032952.1| isochorismatase family protein [Tetrahy... 106 1e-21
ref|ZP_00416936.1| Nicotinamidase [Azotobacter vinelandii A... 106 1e-21
ref|YP_001415264.1| Nicotinamidase [Xanthobacter autotrophi... 106 1e-21
ref|YP_470316.1| pyrazinamidase/nicotinamidase protein [Rhi... 106 1e-21
ref|YP_445581.1| pyrazinamidase/nicotinamidase [Salinibacte... 106 1e-21
ref|ZP_02055269.1| Nicotinamidase [Methylobacterium chlorom... 106 1e-21
ref|YP_275215.1| pyrazinamidase/nicotinamidase [Pseudomonas... 105 2e-21
gb|ABC25334.1| pyrazinamidase/nicotinamidase [uncultured ma... 105 2e-21
ref|ZP_02379340.1| Nicotinamidase [Burkholderia ubonensis Bu] 105 2e-21
ref|YP_001325893.1| Nicotinamidase [Sinorhizobium medicae W... 105 2e-21
ref|YP_507956.1| Nicotinamidase [Jannaschia sp. CCS1] >gi|8... 105 2e-21
ref|XP_812349.1| alpha/beta-hydrolase, putative [Trypanosom... 105 2e-21
ref|XP_001184470.1| PREDICTED: similar to pyrazinamidase/ni... 105 2e-21
ref|ZP_01945589.1| isochorismatase family protein [Coxiella... 105 3e-21
ref|YP_442664.1| pyrazinamidase/nicotinamidase [Burkholderi... 105 3e-21
gb|ACO14708.1| Pyrazinamidase/nicotinamidase [Caligus cleme... 105 3e-21
ref|XP_001201249.1| PREDICTED: similar to pyrazinamidase/ni... 105 3e-21
ref|YP_464529.1| Nicotinamidase [Anaeromyxobacter dehalogen... 104 4e-21
ref|YP_863199.1| bifunctional pyrazinamidase/nicotinamidase... 104 4e-21
ref|YP_001424387.1| isochorismatase family protein [Coxiell... 103 6e-21
ref|ZP_02903192.1| pyrazinamidase/nicotinamidase [Escherich... 103 6e-21
ref|ZP_02120069.1| Nicotinamidase [Methylobacterium nodulan... 103 7e-21
ref|ZP_02218673.1| isochorismatase family protein [Coxiella... 103 8e-21
ref|YP_001204196.1| nicotinamidase/pyrazinamidase [Bradyrhi... 103 8e-21
ref|XP_973348.1| PREDICTED: similar to CG31216-PA [Triboliu... 103 8e-21
ref|YP_001236392.1| Putative pyrazinamidase/nicotinamidase ... 103 8e-21
ref|NP_767317.1| bifunctional pyrazinamidase/nicotinamidase... 103 9e-21
ref|XP_001662895.1| pyrazinamidase/nicotinamidase [Aedes ae... 103 1e-20
ref|ZP_03840187.1| pyrazinamidase/nicotinamidase [Proteus m... 103 1e-20
ref|YP_050436.1| nicotinamidase/pyrazinamidase [Erwinia car... 103 1e-20
ref|YP_236195.1| Nicotinamidase [Pseudomonas syringae pv. s... 103 1e-20
ref|XP_001859965.1| pyrazinamidase/nicotinamidase [Culex pi... 102 1e-20
ref|NP_900934.1| bifunctional pyrazinamidase/nicotinamidase... 102 1e-20
ref|XP_624903.1| PREDICTED: similar to CG31216-PA isoform 2... 102 1e-20
ref|ZP_03825122.1| nicotinamidase/pyrazinamidase [Pectobact... 102 1e-20
ref|ZP_03830114.1| nicotinamidase/pyrazinamidase [Pectobact... 102 1e-20
ref|NP_384685.1| PROBABLE PYRAZINAMIDASE/NICOTINAMIDASE (IN... 102 1e-20
ref|ZP_00833121.1| COG1335: Amidases related to nicotinamid... 102 1e-20
ref|YP_001770067.1| Nicotinamidase [Methylobacterium sp. 4-... 102 2e-20
ref|ZP_01002009.1| pyrazinamidase/nicotinamidase [Loktanell... 102 2e-20
gb|EEH61072.1| predicted protein [Micromonas pusilla CCMP1545] 102 2e-20
ref|YP_001754321.1| Nicotinamidase [Methylobacterium radiot... 102 2e-20
ref|YP_001176409.1| nicotinamidase/pyrazinamidase [Enteroba... 102 2e-20
ref|ZP_02178583.1| pyrazinamidase/nicotinamidase [Hydrogeni... 102 2e-20
ref|ZP_02833934.1| nicotinamidase/pyrazinamidase [Salmonell... 102 2e-20
ref|YP_001086413.1| hypothetical protein A1S_3422 [Acinetob... 102 2e-20
ref|YP_001570719.1| hypothetical protein SARI_01686 [Salmon... 102 2e-20
ref|YP_001003310.1| Nicotinamidase [Halorhodospira halophil... 102 2e-20
ref|YP_001930794.1| isochorismatase hydrolase [Sulfurihydro... 102 2e-20
ref|YP_680973.1| pyrazinamidase/nicotinamidase [Roseobacter... 102 2e-20
ref|XP_001581110.1| isochorismatase family protein [Trichom... 102 2e-20
ref|ZP_02346109.1| nicotinamidase/pyrazinamidase [Salmonell... 102 2e-20
ref|ZP_02669331.1| nicotinamidase/pyrazinamidase [Salmonell... 102 2e-20
ref|YP_001334865.1| nicotinamidase and pyrazinamidase [Kleb... 101 3e-20
ref|XP_001601712.1| PREDICTED: similar to LD05707p [Nasonia... 101 3e-20
ref|XP_001425684.1| hypothetical protein GSPATT00004658001 ... 101 3e-20
ref|NP_456219.1| nicotinamidase/pyrazinamidase [Salmonella ... 101 3e-20
ref|YP_001641346.1| Nicotinamidase [Methylobacterium extorq... 101 4e-20
ref|ZP_02568027.1| nicotinamidase/pyrazinamidase [Salmonell... 101 4e-20
ref|YP_001737248.1| isochorismatase hydrolase [Candidatus K... 101 4e-20
ref|XP_001391911.1| hypothetical protein An07g08360 [Asperg... 101 4e-20
ref|YP_001453362.1| hypothetical protein CKO_01797 [Citroba... 101 4e-20
ref|XP_321695.4| AGAP001435-PA [Anopheles gambiae str. PEST... 101 4e-20
ref|YP_001166243.1| Nicotinamidase [Rhodobacter sphaeroides... 101 5e-20
ref|YP_001588271.1| hypothetical protein SPAB_02051 [Salmon... 100 5e-20
ref|NP_460259.1| nicotinamidase/pyrazinamidase [Salmonella ... 100 6e-20
ref|ZP_00650768.1| Isochorismatase hydrolase [Xylella fasti... 100 7e-20
ref|XP_001601573.1| PREDICTED: similar to pyrazinamidase/ni... 100 8e-20
ref|XP_396928.2| PREDICTED: similar to CG31216-PA [Apis mel... 100 1e-19
ref|ZP_01749818.1| Nicotinamidase [Roseobacter sp. CCS2] >g... 100 1e-19
ref|ZP_02997772.1| hypothetical protein PROSTU_02771 [Provi... 100 1e-19
ref|ZP_02179817.1| pyrazinamidase/nicotinamidase [Hydrogeni... 100 1e-19
ref|YP_865128.1| Nicotinamidase [Magnetococcus sp. MC-1] >g... 99 2e-19
ref|YP_001370254.1| Nicotinamidase [Ochrobactrum anthropi A... 99 2e-19
ref|XP_001455380.1| hypothetical protein GSPATT00002951001 ... 99 2e-19
ref|YP_001379630.1| Nicotinamidase [Anaeromyxobacter sp. Fw... 99 3e-19
ref|NP_732446.1| CG31216 CG31216-PA [Drosophila melanogaste... 98 3e-19
ref|YP_574915.1| Nicotinamidase [Chromohalobacter salexigen... 98 3e-19
ref|YP_216302.1| nicotinamidase/pyrazinamidase [Salmonella ... 98 4e-19
ref|YP_001830086.1| Nicotinamidase [Xylella fastidiosa M23]... 98 5e-19
ref|NP_213680.1| pyrazinamidase/nicotinamidase [Aquifex aeo... 98 5e-19
ref|ZP_02984563.1| isochorismatase hydrolase [Gluconacetoba... 98 5e-19
gb|EEK08332.1| nicotinamidase-like amidase [Brachyspira mur... 97 6e-19
ref|NP_779510.1| pyrazinamidase/nicotinamidase [Xylella fas... 97 6e-19
ref|YP_354449.1| probable pyrazinamidase/nicotinamidase [Rh... 97 7e-19
ref|YP_001907502.1| Pyrazinamidase/nicotinamidase [Erwinia ... 97 8e-19
ref|YP_001238488.1| nicotinamidase/pyrazinamidase [Bradyrhi... 96 2e-18
ref|ZP_00682047.1| Isochorismatase hydrolase [Xylella fasti... 96 3e-18
ref|YP_428084.1| Nicotinamidase [Rhodospirillum rubrum ATCC... 95 3e-18
ref|ZP_01440157.1| bifunctional pyrazinamidase/nicotinamida... 95 3e-18
ref|YP_154496.1| Pyrazinamidase/nicotinamidase [Idiomarina ... 95 3e-18
ref|ZP_02369253.1| pyrazinamidase/nicotinamidase (pncA) [Bo... 95 3e-18
ref|XP_803697.1| alpha/beta-hydrolase-like protein [Trypano... 95 4e-18
ref|XP_967306.1| PREDICTED: similar to CG31216-PA [Triboliu... 94 5e-18
ref|YP_001041928.1| Nicotinamidase [Rhodobacter sphaeroides... 94 6e-18
ref|YP_001438252.1| hypothetical protein ESA_02167 [Enterob... 94 6e-18
ref|YP_001527198.1| bifunctional pyrazinamidase [Azorhizobi... 94 6e-18
ref|ZP_02751610.1| nicotinamidase/pyrazinamidase [Escherich... 94 6e-18
ref|ZP_01252529.1| bifunctional pyrazinamidase/nicotinamida... 94 7e-18
ref|ZP_02463173.1| pyrazinamidase/nicotinamidase [Burkholde... 94 8e-18
ref|XP_001260011.1| isochorismatase family hydrolase, puta... 94 8e-18
ref|NP_045429.1| pyrazinamidase/nicotinamidase (pncA) [Borr... 94 1e-17
ref|YP_115158.1| pyrazinamidase/nicotinamidase, putative [M... 92 2e-17
emb|CAK98523.1| hypothetical pyrazinamidase/nicotinamidase ... 91 4e-17
ref|YP_522109.1| isochorismatase hydrolase [Rhodoferax ferr... 91 6e-17
ref|ZP_02519725.1| pyrazinamidase/nicotinamidase (pncA) [Bo... 91 6e-17
ref|NP_627144.1| nicotinamidase [Streptomyces coelicolor A3... 91 7e-17
ref|NP_499876.1| Y38C1AA.3 [Caenorhabditis elegans] >gi|145... 90 1e-16
ref|YP_424801.1| pyrazinamidase/nicotinamidase [Mycoplasma ... 89 2e-16
gb|ABV02586.1| Pyrazinamidase and nicotinamidase protein 1,... 89 2e-16
ref|YP_001233233.1| Nicotinamidase [Acidiphilium cryptum JF... 89 3e-16
gb|EEH48303.1| nicotinamidase [Paracoccidioides brasiliensi... 88 4e-16
ref|XP_001671258.1| Hypothetical protein CBG01661 [Caenorha... 88 4e-16
ref|ZP_01225532.1| amidase [Aurantimonas sp. SI85-9A1] >gi|... 88 4e-16
ref|NP_355032.2| pyrazinamidase/nicotinamidase [Agrobacteri... 87 8e-16
gb|EDU43737.1| pyrazinamidase/nicotinamidase [Pyrenophora t... 87 8e-16
ref|YP_001230506.1| isochorismatase hydrolase [Geobacter ur... 86 3e-15
gb|AAV33207.1| truncated pyrazinamidase [Mycobacterium tube... 85 4e-15
ref|ZP_02998437.1| Pyrazinamidase/nicotinamidase [Mycoplasm... 85 4e-15
ref|ZP_02165609.1| pyrazinamidase/nicotinamidase [Hoeflea p... 85 4e-15
ref|XP_001462660.1| alpha/beta-hydrolase-like protein [Leis... 84 5e-15
ref|XP_001561491.1| alpha/beta-hydrolase-like protein [Leis... 84 5e-15
gb|AAV33195.1| pyrazinamidase [Mycobacterium tuberculosis] 84 6e-15
ref|NP_975984.1| pyrazinamidase/nicotinamidase [Mycoplasma ... 84 6e-15
ref|NP_216559.1| PYRAZINAMIDASE/NICOTINAMIDAS PNCA (PZase) ... 84 8e-15
>ref|NP_011478.1| Nicotinamidase that converts nicotinamide to nicotinic acid as part
of the NAD(+) salvage pathway, required for life span
extension by calorie restriction; PNC1 expression
responds to all known stimuli that extend replicative
life span; Pnc1p [Saccharomyces cerevisiae]
sp|P53184|PNC1_YEAST Nicotinamidase (Nicotine deamidase) (NAMase)
pdb|2H0R|A Chain A, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|B Chain B, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|C Chain C, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|D Chain D, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|E Chain E, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|F Chain F, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|G Chain G, Structure Of The Yeast Nicotinamidase Pnc1p
emb|CAA96739.1| unnamed protein product [Saccharomyces cerevisiae]
gb|AAS56807.1| YGL037C [Saccharomyces cerevisiae]
gb|EDN61566.1| nicotinamidase [Saccharomyces cerevisiae YJM789]
Length = 216
Score = 424 bits (1090), Expect = e-117, Method: Composition-based stats.
Identities = 216/216 (100%), Positives = 216/216 (100%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF
Sbjct: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV
Sbjct: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY
Sbjct: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK
Sbjct: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
>ref|XP_444840.1| hypothetical protein CAGL0A01716g [Candida glabrata CBS138]
emb|CAG57733.1| unnamed protein product [Candida glabrata CBS 138]
Length = 211
Score = 258 bits (658), Expect = 3e-67, Method: Composition-based stats.
Identities = 129/213 (60%), Positives = 172/213 (80%), Gaps = 3/213 (1%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
MKTL+V+D+QNDFI+P S+ VP+GEE+++PI +LM+D WHR+VV+RDWHP HISF
Sbjct: 1 MKTLLVIDVQNDFITPDHSMYVPQGEEVVSPIVELMKDPQ--WHRVVVSRDWHPQNHISF 58
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
AKNH E Y+ TY SPRPGDDSTQ LWPVHCV+NT G+QL I++ V +KHIKIV
Sbjct: 59 AKNH-GVEDYTETTYKSPRPGDDSTQPATLWPVHCVQNTRGAQLAPDILELVNSKHIKIV 117
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
DKG+L++ EYYSAF+D W +HKT++++YL+KHHT EVY+VG+AL++CVK TAISAA+LGY
Sbjct: 118 DKGYLSNCEYYSAFNDTWEWHKTELDEYLKKHHTTEVYVVGLALDFCVKNTAISAAKLGY 177
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
TT+L DYT+PI D + +++++LK HN+ V
Sbjct: 178 DTTILKDYTKPIYTDEDHQQQLEKDLKEHNVKV 210
>ref|XP_456073.1| unnamed protein product [Kluyveromyces lactis]
emb|CAG98781.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
Length = 218
Score = 211 bits (537), Expect = 2e-53, Method: Composition-based stats.
Identities = 98/214 (45%), Positives = 153/214 (71%), Gaps = 5/214 (2%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L+V+D+QNDF+ P GSL V G+ +I+P+ L+QD +DW + +T+DWHP HISFA
Sbjct: 4 RALLVIDIQNDFLPPKGSLAVQDGDTIIDPVIQLLQD--QDWDCVAMTKDWHPPDHISFA 61
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHI--KI 119
KNH + +S++TY SP PG Q LWPVHCV+ TWGS++ ++++ +++ + KI
Sbjct: 62 KNHGLPD-FSSFTYDSPVPGSTEKQSATLWPVHCVQETWGSEVPEKLLAEILKLKVPHKI 120
Query: 120 VDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELG 179
V+KG+L+DREYYS F+DIWN H T+++ + +++ E+Y+VG+A ++CVK +AISAA LG
Sbjct: 121 VNKGYLSDREYYSGFNDIWNDHHTELDAFFKENDVTEIYVVGLAFDFCVKNSAISAANLG 180
Query: 180 YKTTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
Y T+L DYT+ I++D + I +EL + ++V
Sbjct: 181 YHVTILKDYTKAIANDLQSIESFIQELAKNEVSV 214
>ref|NP_986013.1| AFR466Cp [Ashbya gossypii ATCC 10895]
gb|AAS53837.1| AFR466Cp [Ashbya gossypii ATCC 10895]
Length = 218
Score = 192 bits (487), Expect = 2e-47, Method: Composition-based stats.
Identities = 97/210 (46%), Positives = 129/210 (61%), Gaps = 4/210 (1%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
K LIVVD+QNDF G+L VP E++ P+++L QD W + +TRDWHP H+SFA
Sbjct: 3 KALIVVDVQNDFADARGALAVPGAHEIVQPLAELAQDPR--WAYVAMTRDWHPPDHVSFA 60
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H + P+S Y YH P Q G LWP HCV+ +WG+QL Q+ H +VD
Sbjct: 61 DTH-GRPPFSPYMYHPPPGVRAPPQAGTLWPTHCVQGSWGAQLAPQLAAARSLPH-SVVD 118
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG DRE YSAF DIW + ++ L H VY+ G+AL+YCVK+TAISAA LGY
Sbjct: 119 KGVWPDRECYSAFEDIWADRSSGLDGLLRSHGVKHVYVAGLALDYCVKSTAISAARLGYT 178
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNI 211
TT+LLDYTR I+ D + + ++ +L H +
Sbjct: 179 TTILLDYTRAIAADAQSMARLSSDLAGHQV 208
>ref|XP_001644836.1| hypothetical protein Kpol_1041p36 [Vanderwaltozyma polyspora DSM
70294]
gb|EDO16978.1| hypothetical protein Kpol_1041p36 [Vanderwaltozyma polyspora DSM
70294]
Length = 179
Score = 153 bits (387), Expect = 8e-36, Method: Composition-based stats.
Identities = 78/171 (45%), Positives = 117/171 (68%), Gaps = 4/171 (2%)
Query: 43 WHRIVVTRDWHPSRHISFAKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGS 102
W IV+TRDWH H+SFAKNH + ++ + Y SP D+ E LWPVHC+++T G+
Sbjct: 6 WDSIVLTRDWHCKDHVSFAKNH-NLPNFAPFVYCSPVVNDERKIESTLWPVHCIEDTEGA 64
Query: 103 QLVDQIMDQVVTKH--IKIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIV 160
+ + V+ KH I +V+KG+L DREYYSAF DIW+ H T++++ L++ DEV +V
Sbjct: 65 DIAPS-LQAVLRKHPEIVLVNKGYLKDREYYSAFCDIWDDHNTELHEILQQDGIDEVVVV 123
Query: 161 GVALEYCVKATAISAAELGYKTTVLLDYTRPISDDPEVINKVKEELKAHNI 211
G+AL+YCVK +AISAA+LGYKTT+L YTR I + + + ++ +E + + +
Sbjct: 124 GLALDYCVKNSAISAAKLGYKTTILKKYTRAIDNHKDSLRRLAKEFEYYGV 174
>ref|XP_001523752.1| hypothetical protein LELG_05168 [Lodderomyces elongisporus NRRL
YB-4239]
gb|EDK46987.1| hypothetical protein LELG_05168 [Lodderomyces elongisporus NRRL
YB-4239]
Length = 219
Score = 148 bits (373), Expect = 3e-34, Method: Composition-based stats.
Identities = 80/217 (36%), Positives = 123/217 (56%), Gaps = 10/217 (4%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
K L+VVD+Q DF+ P GSL + + +E+I+ I D++ + D + + T DWHP+ H SFA
Sbjct: 4 KALVVVDLQEDFLEPTGSLKIKRSKEIISQIIDILHEKTFDLY--IATLDWHPANHTSFA 61
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVD---QIMDQVVTKHIK 118
H EP++ +H P G+ Q +WP HC++NT GS+L + D++ T
Sbjct: 62 SQH-GVEPFTELEFHHPETGEAKKQ--FVWPDHCIQNTHGSRLAPSFAEAFDKLPTNKKS 118
Query: 119 IVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAEL 178
I+ KG+L DREYYS F D W H T++ L+ + EV VG+A +YCV +AI A
Sbjct: 119 IIKKGYLQDREYYSCFQDTWGIHHTEIEGLLKDNQIKEVTFVGLAYDYCVLNSAIDCAHQ 178
Query: 179 GYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
+KT V+ R +S++ + + K + + VVD
Sbjct: 179 KFKTFVVKSLCRSVSEEND--ERTTTMYKKNGVTVVD 213
>ref|XP_500320.1| hypothetical protein [Yarrowia lipolytica]
emb|CAG84258.1| unnamed protein product [Yarrowia lipolytica CLIB122]
Length = 203
Score = 146 bits (369), Expect = 8e-34, Method: Composition-based stats.
Identities = 87/214 (40%), Positives = 127/214 (59%), Gaps = 11/214 (5%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M LI+VD+QNDF+ P GSL V G ++I PI + D+ + + +V T+D HP H SF
Sbjct: 1 MAALIIVDLQNDFL-PGGSLAVVDGNDII-PIVQKLADSGK-YKFVVATKDSHPQDHTSF 57
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
A NH EP+++ T+ P D + +WPVHCV+ T G+ V +V
Sbjct: 58 AANH-GAEPFTSITFK--HPNSDKQVDHTVWPVHCVEGTSGADYPPSFDSSNVQA---LV 111
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KG+L DREYYS F D+W HKT+++ L+++ EV +VG+A +YCV TA AA+ GY
Sbjct: 112 RKGYLQDREYYSGFEDVWGIHKTELHDLLQQNGVTEVDVVGLAFDYCVFNTAKDAAKRGY 171
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
KTTV+ + T+P+ DP K+ L+ ++VV
Sbjct: 172 KTTVIREATKPV--DPSSEKKIVASLEEAGVHVV 203
>ref|XP_888958.1| hypothetical protein CaJ7.0402 [Candida albicans SC5314]
dbj|BAE44855.1| hypothetical protein [Candida albicans]
Length = 244
Score = 145 bits (367), Expect = 1e-33, Method: Composition-based stats.
Identities = 87/231 (37%), Positives = 126/231 (54%), Gaps = 21/231 (9%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADR----DWHRIVVTRDWHPSRHIS 59
LIVVD+Q DF+ P GSL + G +I I+ L+ D DW IV T+DWHP H S
Sbjct: 6 LIVVDLQEDFLPPNGSLAIKNGRSVIPKINQLLPSQDNHSKFDWSLIVATQDWHPPNHTS 65
Query: 60 FAKNHKDKEPYSTYTY-HSPRPGDDSTQE-----GILWPVHCVKNTWGSQLVDQIMDQV- 112
FA H++ P++ + H + D T + I+WP HCV+ T G+QL +Q
Sbjct: 66 FASQHENVAPFTEIEFIHPEKKLDPKTNQPIVMNQIVWPDHCVQGTKGAQLEPSFANQFE 125
Query: 113 -VTKH-------IKIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVAL 164
+TK KIV KG+L DREYYS F D W H T++ L ++ + V VG+A
Sbjct: 126 KLTKQDDNNTAPCKIVKKGYLPDREYYSCFQDCWGLHHTELIDLLHEYDIENVVFVGLAY 185
Query: 165 EYCVKATAISAAELGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
++CV ++AI +A+ G+KT VL +Y + PE IN + + + +VD
Sbjct: 186 DFCVLSSAIDSAKNGFKTFVLKNYCESVY--PEKINDTDKLFIDNGVTIVD 234
>ref|XP_458267.1| hypothetical protein DEHA0C14564g [Debaryomyces hansenii CBS767]
emb|CAG86344.1| unnamed protein product [Debaryomyces hansenii CBS767]
Length = 234
Score = 144 bits (362), Expect = 5e-33, Method: Composition-based stats.
Identities = 76/203 (37%), Positives = 113/203 (55%), Gaps = 14/203 (6%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+VVD+Q DF+ GSL V +G ++ I++L+ W ++ T+DWHP H SFA
Sbjct: 7 LVVVDLQEDFLPDNGSLAVAEGRSIVPLINELLNTEKYRWSAVIATQDWHPEDHCSFASQ 66
Query: 64 HKDKEPYSTYTYHSP-----RPGDDSTQEGILWPVHCVKNTWGSQLVDQI------MDQV 112
HK PYS + P G+ TQ ++WP HC++N++GS+L Q +D
Sbjct: 67 HK-VSPYSEMEFKHPLGERDTNGEIRTQMQVVWPDHCIQNSFGSKLDPQFEAAFNQLDPN 125
Query: 113 VTKHIKIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATA 172
+ + IV KG+L DREYYS F D W HKT+M YL +V VG+A ++CV +A
Sbjct: 126 IPR--TIVKKGYLKDREYYSCFQDCWKLHKTEMQDYLRNLGISDVVFVGIAYDFCVLNSA 183
Query: 173 ISAAELGYKTTVLLDYTRPISDD 195
+ A+ G+ T V+ D + + D
Sbjct: 184 LDCAKSGFNTYVIKDCCKSVFPD 206
>ref|XP_001482603.1| hypothetical protein PGUG_05623 [Pichia guilliermondii ATCC 6260]
gb|EDK41525.1| hypothetical protein PGUG_05623 [Pichia guilliermondii ATCC 6260]
Length = 231
Score = 139 bits (351), Expect = 1e-31, Method: Composition-based stats.
Identities = 81/218 (37%), Positives = 128/218 (58%), Gaps = 12/218 (5%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L++VD+QNDF+ P GSL VP G E+IN I +L+ + ++ T+DWHPS H SFA
Sbjct: 6 LVIVDLQNDFLPPHGSLAVPGGNEIINNIINLLDPHKYRFLAVIATQDWHPSDHCSFASQ 65
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGI-----LWPVHCVKNTWGSQL---VDQIMDQVVTK 115
H EPY++ + P D + I LWP HC++NT G++L +++ +++
Sbjct: 66 H-GSEPYTSKVFEHPENKKDQHGKTITLNQTLWPDHCIQNTEGAELELEFEKVFNKLEVP 124
Query: 116 HIKIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISA 175
H I+ KG+L DREYYS F D W+ H T++N+YL+ + +V G+A +YCV +AI +
Sbjct: 125 H-TIIKKGYLKDREYYSCFGDCWDLHHTEINQYLKDNGITDVVFAGLAYDYCVLQSAIDS 183
Query: 176 AELGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
+ GYKT V+ + + + P+ + ++H I V
Sbjct: 184 VKKGYKTYVVKEACKNVY--PQKMPLTDNIYRSHGITV 219
>ref|ZP_02061772.1| pyrazinamidase/nicotinamidase (PZAase)(Nicotine deamidase) (NAMase)
[Rickettsiella grylli]
gb|EDP45777.1| pyrazinamidase/nicotinamidase (PZAase)(Nicotine deamidase) (NAMase)
[Rickettsiella grylli]
Length = 205
Score = 132 bits (333), Expect = 1e-29, Method: Composition-based stats.
Identities = 80/217 (36%), Positives = 128/217 (58%), Gaps = 24/217 (11%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
K LI+VD+QNDF+ P G+L V K +E+I P+++ +Q + + ++ T+DWHP HI FA
Sbjct: 3 KALILVDLQNDFM-PGGALAVDKADEVI-PVANRVQ---QQFKYVIATQDWHPEDHICFA 57
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGI---LWPVHCVKNTWGSQLVDQI-MDQVVTKHI 117
KNH H PG+ Q G+ LWPVHCV+NT G++ V + +D + I
Sbjct: 58 KNH-----------HGHFPGEFIHQAGLSQMLWPVHCVQNTKGAEFVKNLKLDHI----I 102
Query: 118 KIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAE 177
K+V KG + + YS F + + T + ++L+K E+YI+GVA +YCVK T + + +
Sbjct: 103 KVVRKGSNPNVDSYSGFFENDHQKATGLAEFLKKLQITELYIMGVATDYCVKYTVLDSCK 162
Query: 178 LGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
LG+KT ++ D R ++ +PE E+KA + ++
Sbjct: 163 LGFKTYLIEDGCRAVNVNPEDGRLAISEMKAVGVKII 199
>ref|XP_001874048.1| predicted protein [Laccaria bicolor S238N-H82]
gb|EDR15840.1| predicted protein [Laccaria bicolor S238N-H82]
Length = 223
Score = 132 bits (332), Expect = 2e-29, Method: Composition-based stats.
Identities = 78/212 (36%), Positives = 116/212 (54%), Gaps = 12/212 (5%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
LIV+D+QNDF+S GSL VP G E+++ ++ L+ D + + T+D+HP+ H+SFA
Sbjct: 11 LIVIDLQNDFVS--GSLPVPGGAEIVDTVNRLV---DLPFALKIATKDFHPANHVSFALR 65
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
H +H E +LWP HCV T G+ V + T I+ KG
Sbjct: 66 HDLPVFTKATIFHPSDKARTKGLEQVLWPAHCVVGTSGANFVPGLNTDDFTT---IIHKG 122
Query: 124 FLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTT 183
D E YSAF DIW++ +D+ + L K + +V+ VG+A +YCVK TA+ +A G+ T
Sbjct: 123 VDPDIESYSAFRDIWHYQNSDLTRVLHKENVTDVFFVGLAGDYCVKYTALDSASFGFDTW 182
Query: 184 VLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
V+ D R ISDD N +E++ I V+
Sbjct: 183 VVRDAVRCISDD----NIAWDEMEKKGIRFVE 210
>ref|XP_364131.1| hypothetical protein MGG_08976 [Magnaporthe grisea 70-15]
gb|EDK05194.1| hypothetical protein MGG_08976 [Magnaporthe grisea 70-15]
Length = 230
Score = 132 bits (331), Expect = 2e-29, Method: Composition-based stats.
Identities = 79/216 (36%), Positives = 125/216 (57%), Gaps = 12/216 (5%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
LIVVD+Q DF P GSL VP G + I+ L+ + V T+DWHP H+SFA N
Sbjct: 12 LIVVDLQEDFCPPNGSLAVPDGRAVAPVINKLLTSTA--FVTRVATKDWHPQSHVSFAAN 69
Query: 64 HKDKEPYSTY-TYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
H KEP+ + T +P G +S E LWPVHCV++T G+ L+ ++ + + ++++K
Sbjct: 70 HVSKEPFIDFVTITNPLNGSES-YETRLWPVHCVQDTPGAALIPELD---LGRIDEVLEK 125
Query: 123 GFLTDREYYSAFHDIWNFHK---TDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELG 179
G +D E YSAF+ + + + L + VY+VG+A +YCV++TA+ AA G
Sbjct: 126 GIRSDVEMYSAFYPPLKDPRVGDSGLAGLLREKGISHVYVVGLAADYCVRSTALDAAAEG 185
Query: 180 YKTTVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
+ T ++ + T+P+ DP V++E+ A + +VD
Sbjct: 186 FVTVIVEEGTKPV--DPAAWPTVRQEIIASGVGIVD 219
>ref|XP_001385959.2| NAD(+) salvage pathway gene [Pichia stipitis CBS 6054]
gb|ABN67930.2| NAD(+) salvage pathway gene [Pichia stipitis CBS 6054]
Length = 235
Score = 129 bits (325), Expect = 1e-28, Method: Composition-based stats.
Identities = 73/222 (32%), Positives = 119/222 (53%), Gaps = 13/222 (5%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L V+D+Q DF+ P GSL V +G +I I+DL+ + W ++ T+DWHPS H SFA
Sbjct: 8 LAVIDLQEDFLPPHGSLAVAQGRSVIPLINDLVTNRQFKWSAVIATQDWHPSDHTSFASQ 67
Query: 64 HKDKEPYSTYTYHSPRPGDDST------QEGILWPVHCVKNTWGSQLVDQIMDQV--VTK 115
H P++ + P D ++ ++WP HCV+ + G+ + + ++
Sbjct: 68 H-GVAPFTELEFKHPLDEKDPVTNEVIIKKQVVWPDHCVQESSGACIDASFLGNFNSISP 126
Query: 116 HI--KIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAI 173
+I +V KG+L+DREYYS F D W H T+M K+L + +V VG+A +YCV +A
Sbjct: 127 NIVKTVVKKGYLSDREYYSCFQDTWGLHHTEMEKFLRDNKITDVIFVGLAYDYCVFNSAK 186
Query: 174 SAAELGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
+A G+ T VL + + PE + E + N+ +++
Sbjct: 187 DSAADGFNTYVLKKCCKSVY--PEKEAETDELYRKANVTIIE 226
>ref|ZP_02965199.1| isochorismatase hydrolase [bacterium Ellin514]
gb|EDU05487.1| isochorismatase hydrolase [bacterium Ellin514]
Length = 208
Score = 128 bits (321), Expect = 3e-28, Method: Composition-based stats.
Identities = 73/194 (37%), Positives = 116/194 (59%), Gaps = 16/194 (8%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
MK LI+VD+QNDF+ P G+L VP G+ ++ P+++ +Q + + I+ T+DWHP H SF
Sbjct: 1 MKALILVDLQNDFL-PGGALAVPHGDTVL-PLANKLQSS---FKLILATQDWHPINHSSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
A NH + P T ++ LWPVHCV+NT G+++ +M + K K+
Sbjct: 56 AVNHPGRTPGETVVL--------KKRQQKLWPVHCVQNTRGAEITTGLM---MNKVNKVF 104
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KG + + +S F D + T + +YL++ EVYI+G+A +YCVKATA+ A LG+
Sbjct: 105 KKGVDVEIDSHSGFFDNDHQRSTGLGEYLKEKKVKEVYILGLATDYCVKATALDAVALGF 164
Query: 181 KTTVLLDYTRPISD 194
KT ++ D R +++
Sbjct: 165 KTHLIEDACRGVNE 178
>ref|XP_001245038.1| hypothetical protein CIMG_04479 [Coccidioides immitis RS]
gb|EAS33455.1| hypothetical protein CIMG_04479 [Coccidioides immitis RS]
Length = 243
Score = 127 bits (319), Expect = 6e-28, Method: Composition-based stats.
Identities = 87/223 (39%), Positives = 123/223 (55%), Gaps = 19/223 (8%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
LIVVDMQ DF P L V G EL+ I++L+ + + T+D+HP+ HISFA N
Sbjct: 14 LIVVDMQEDFCYP-NPLGVRGGRELVPLINELI--GYPGFVLRIATQDFHPATHISFATN 70
Query: 64 HK--DKEPYSTY-TYHSPRPGDDS-TQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKI 119
H + +P+ +Y T +P PG +S T LWPVHCV++T G++L+ I + K I
Sbjct: 71 HPAPNNKPFESYITMKNPAPGKESITMPQRLWPVHCVQHTPGAELLPGIEKE---KFDLI 127
Query: 120 VDKGFLTDREYYSAFHDIWNF--------HKTDMNKYLEKHHTDEVYIVGVALEYCVKAT 171
V KG E YSAF D + D+ L ++ +V++VGVA YCVK T
Sbjct: 128 VRKGMDERVEMYSAFADAFGNTDCVASGGASADLETALRENQVTDVFVVGVAGSYCVKFT 187
Query: 172 AISAAELGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
AI A E G+ V+ + TR + D+ +V N+ K EL H + VV
Sbjct: 188 AIDAMERGFNAYVIEEGTRCV-DEGDVWNETKAELAGHGVKVV 229
>ref|ZP_01853806.1| pyrazinamidase/nicotinamidase [Planctomyces maris DSM 8797]
gb|EDL60134.1| pyrazinamidase/nicotinamidase [Planctomyces maris DSM 8797]
Length = 199
Score = 126 bits (317), Expect = 8e-28, Method: Composition-based stats.
Identities = 77/218 (35%), Positives = 127/218 (58%), Gaps = 22/218 (10%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M+ LI+VD+Q DF+ P GSL VP+G++++ ++LM D D +V T+DWHP+ H+SF
Sbjct: 1 MRALILVDLQYDFM-PGGSLAVPEGDQVVPIANELMSDFDL----VVATQDWHPADHLSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQL-VDQIMDQVVTKHIKI 119
A H D+E D + E ILWP HCV+ T G++L D +Q+ +I
Sbjct: 56 ASQHPDREIGEQI--------DLAGLEQILWPDHCVQGTRGAELHADLKQNQL----DRI 103
Query: 120 VDKGFLTDR--EYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAE 177
KG TDR + YS F+D + T M +YL++ V ++G+A +YCVK TA+ A +
Sbjct: 104 FPKG--TDRLIDSYSGFYDNGHQKSTGMGEYLKEQGVQSVTVLGLAADYCVKWTALDAVK 161
Query: 178 LGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
LG++T++ L R + P +++ +E++ + +++
Sbjct: 162 LGFQTSLSLRGCRGVDLSPGDVHRAYQEMQNAGVEIIE 199
>ref|XP_001829253.1| hypothetical protein CC1G_06590 [Coprinopsis cinerea okayama7#130]
gb|EAU92579.1| hypothetical protein CC1G_06590 [Coprinopsis cinerea okayama7#130]
Length = 237
Score = 126 bits (317), Expect = 1e-27, Method: Composition-based stats.
Identities = 78/202 (38%), Positives = 112/202 (55%), Gaps = 7/202 (3%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+ +DMQNDF+S GSL VP G E I PI + + D + V TRD+HP H+SFA+
Sbjct: 25 LVAIDMQNDFVS--GSLAVP-GAEAIIPIVNALIDHP-GFKFKVATRDFHPDNHVSFAQT 80
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
H +H E +LWPVHCV NT G++ V ++ K IV KG
Sbjct: 81 HNKPVLSKAIIFHPEDKDKLMGLEQVLWPVHCVANTEGAEFVPGLIKD---KFDHIVHKG 137
Query: 124 FLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTT 183
D E YSAF DIW H +++ + L++ +V+ VG+A +YCVK TAI + G+++
Sbjct: 138 THPDIESYSAFKDIWGKHTSELPEMLKEKKITDVFYVGLAGDYCVKYTAIDSVSFGFRSW 197
Query: 184 VLLDYTRPISDDPEVINKVKEE 205
V++D + IS D +K+ E
Sbjct: 198 VVVDGVKSISSDCVAWDKMATE 219
>ref|ZP_01955355.1| pyrazinamidase/nicotinamidase [Vibrio cholerae MZO-3]
ref|ZP_01977031.1| pyrazinamidase/nicotinamidase [Vibrio cholerae MZO-2]
ref|ZP_01981859.1| pyrazinamidase/nicotinamidase [Vibrio cholerae 623-39]
gb|EAY42487.1| pyrazinamidase/nicotinamidase [Vibrio cholerae MZO-3]
gb|EDL73440.1| pyrazinamidase/nicotinamidase [Vibrio cholerae 623-39]
gb|EDM55947.1| pyrazinamidase/nicotinamidase [Vibrio cholerae MZO-2]
Length = 206
Score = 125 bits (314), Expect = 2e-27, Method: Composition-based stats.
Identities = 74/194 (38%), Positives = 107/194 (55%), Gaps = 23/194 (11%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
K L++VD+QNDF SP G+L VP G+ ++ I+ L+ + ++ T+DWHP++H SFA
Sbjct: 3 KALLLVDVQNDF-SPSGALPVPDGDAVVPVINQLLPL----FEHVIATKDWHPAKHASFA 57
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGI---LWPVHCVKNTWGSQLVDQIMDQVVTKHIK 118
+ PG+ GI +WP HCV+NT G++ + + Q +T
Sbjct: 58 ------------SVQGKTPGEVIDLNGIPQVMWPDHCVQNTHGAEFIAGLDVQRITH--- 102
Query: 119 IVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAEL 178
IV KG D + YS F D FH T + +YL H EVYI G+A +YCVK TA+ A L
Sbjct: 103 IVTKGTHLDVDSYSGFFDNQRFHATGLAEYLSNHGISEVYIAGLATDYCVKYTALDAVSL 162
Query: 179 GYKTTVLLDYTRPI 192
+KT V+ D R +
Sbjct: 163 YFKTWVIQDACRGV 176
>ref|XP_001593095.1| hypothetical protein SS1G_06017 [Sclerotinia sclerotiorum 1980]
gb|EDO03536.1| hypothetical protein SS1G_06017 [Sclerotinia sclerotiorum 1980]
Length = 232
Score = 124 bits (312), Expect = 4e-27, Method: Composition-based stats.
Identities = 77/208 (37%), Positives = 117/208 (56%), Gaps = 11/208 (5%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
LI+VD+Q DF+ P GSL V G + I I++L+ + +H + T+DWHPS H SFA N
Sbjct: 15 LIIVDLQEDFLPPNGSLAVANGRDTIPIINNLL---NLPFHLKIATKDWHPSNHTSFASN 71
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
H +P++ +T T + LWP HCV+NT GS+ ++ +TK + KG
Sbjct: 72 HPGTKPFTDFTTIINPSNPSETYKTRLWPPHCVQNTLGSEFPFELNTTQITKTLL---KG 128
Query: 124 FLTDREYYSAFHD-IWNFHKTD--MNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
D E YSAF+D + N +D + L+ +VY+VG+A +YCVK TA +A+ G+
Sbjct: 129 QHPDVEVYSAFYDPLKNPRCSDSGLAGQLKDEGITDVYVVGLAADYCVKCTAEDSAKEGF 188
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKA 208
T +L + TR + DP K++ L+
Sbjct: 189 NTFILEEGTRAV--DPAEWEKIRSSLEG 214
>ref|ZP_03823780.1| nicotinamidase-like amidase [Acinetobacter sp. ATCC 27244]
gb|EEH68325.1| nicotinamidase-like amidase [Acinetobacter sp. ATCC 27244]
Length = 219
Score = 124 bits (311), Expect = 5e-27, Method: Composition-based stats.
Identities = 75/189 (39%), Positives = 111/189 (58%), Gaps = 16/189 (8%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
LIVVD+QN F +P G+L V +++I I+ L + +V+T+DWHP +HISFA N
Sbjct: 14 LIVVDVQNGF-TPGGNLAVADADQIIPLINRLAPQ----FEHVVLTQDWHPDQHISFADN 68
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
HK+K+P+ T S +LWP HCV+ T ++ ++ Q+ T + I+ KG
Sbjct: 69 HKNKQPFETIEL--------SYGTQVLWPKHCVQGTHDAEFHSEL--QIPTAQL-IIRKG 117
Query: 124 FLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTT 183
+ YSAF + T +N YL++H D VYIVG+A ++CV TAI AA+LG+KT
Sbjct: 118 VHQHIDSYSAFMEADRQTPTGLNGYLKEHQIDTVYIVGIATDFCVAWTAIDAADLGFKTY 177
Query: 184 VLLDYTRPI 192
V+ D + I
Sbjct: 178 VIEDACKAI 186
>ref|ZP_01675333.1| pyrazinamidase/nicotinamidase [Vibrio cholerae 2740-80]
ref|ZP_01679232.1| pyrazinamidase/nicotinamidase [Vibrio cholerae V52]
ref|YP_001215490.1| pyrazinamidase/nicotinamidase [Vibrio cholerae O395]
ref|ZP_01947701.1| pyrazinamidase/nicotinamidase [Vibrio cholerae 1587]
ref|ZP_01951458.1| pyrazinamidase/nicotinamidase [Vibrio cholerae MAK 757]
ref|ZP_01971262.1| pyrazinamidase/nicotinamidase [Vibrio cholerae NCTC 8457]
gb|EAX60168.1| pyrazinamidase/nicotinamidase [Vibrio cholerae 2740-80]
gb|EAX64065.1| pyrazinamidase/nicotinamidase [Vibrio cholerae V52]
gb|EAY35750.1| pyrazinamidase/nicotinamidase [Vibrio cholerae 1587]
gb|EAY39192.1| pyrazinamidase/nicotinamidase [Vibrio cholerae MAK 757]
gb|EAZ73472.1| pyrazinamidase/nicotinamidase [Vibrio cholerae NCTC 8457]
gb|ABQ18522.1| pyrazinamidase/nicotinamidase [Vibrio cholerae O395]
Length = 206
Score = 123 bits (308), Expect = 1e-26, Method: Composition-based stats.
Identities = 73/194 (37%), Positives = 106/194 (54%), Gaps = 23/194 (11%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
K L++VD+QNDF SP G+L VP G+ ++ I+ L+ + ++ T+DWHP++H SFA
Sbjct: 3 KALLLVDVQNDF-SPSGALPVPDGDAIVPVINQLLPL----FEHVIATKDWHPAKHASFA 57
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGI---LWPVHCVKNTWGSQLVDQIMDQVVTKHIK 118
+ PG+ GI +WP HCV+NT G++ + + Q +T
Sbjct: 58 ------------SVQGKTPGEVIDLNGIPQVMWPDHCVQNTHGAEFIAGLDVQRITH--- 102
Query: 119 IVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAEL 178
IV KG D + YS F D FH T + +YL EVYI G+A +YCVK TA+ A L
Sbjct: 103 IVTKGTHLDVDSYSGFFDNQRFHATGLAEYLSNQGISEVYIAGLATDYCVKYTALDAVSL 162
Query: 179 GYKTTVLLDYTRPI 192
+KT V+ D R +
Sbjct: 163 YFKTWVIQDACRGV 176
>ref|NP_233099.1| pyrazinamidase/nicotinamidase [Vibrio cholerae O1 biovar eltor str.
N16961]
ref|ZP_01480144.1| hypothetical protein VchoM_02000674 [Vibrio cholerae MO10]
ref|ZP_01483348.1| hypothetical protein VchoR_02000701 [Vibrio cholerae RC385]
ref|ZP_01486229.1| hypothetical protein VchoV5_02001161 [Vibrio cholerae V51]
ref|ZP_01973391.1| pyrazinamidase/nicotinamidase [Vibrio cholerae B33]
gb|AAF96611.1| pyrazinamidase/nicotinamidase [Vibrio cholerae O1 biovar eltor str.
N16961]
gb|EAZ48076.1| pyrazinamidase/nicotinamidase [Vibrio cholerae MO10]
gb|EAZ50611.1| pyrazinamidase/nicotinamidase [Vibrio cholerae V51]
gb|EAZ78990.1| pyrazinamidase/nicotinamidase [Vibrio cholerae B33]
gb|EDN13736.1| pyrazinamidase/nicotinamidase [Vibrio cholerae RC385]
Length = 206
Score = 122 bits (307), Expect = 1e-26, Method: Composition-based stats.
Identities = 73/194 (37%), Positives = 106/194 (54%), Gaps = 23/194 (11%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
K L++VD+QNDF SP G+L VP G+ ++ I+ L+ + ++ T+DWHP++H SFA
Sbjct: 3 KALLLVDVQNDF-SPSGALPVPDGDAVVPVINQLLPL----FEHVIATKDWHPAKHASFA 57
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGI---LWPVHCVKNTWGSQLVDQIMDQVVTKHIK 118
+ PG+ GI +WP HCV+NT G++ + + Q +T
Sbjct: 58 ------------SVQGKTPGEVIDLNGIPQVMWPDHCVQNTHGAEFIAGLDVQRITH--- 102
Query: 119 IVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAEL 178
IV KG D + YS F D FH T + +YL EVYI G+A +YCVK TA+ A L
Sbjct: 103 IVTKGTHLDVDSYSGFFDNQRFHATGLAEYLSNQGISEVYIAGLATDYCVKYTALDAVSL 162
Query: 179 GYKTTVLLDYTRPI 192
+KT V+ D R +
Sbjct: 163 YFKTWVIQDACRGV 176
>gb|EDN16169.1| pyrazinamidase/nicotinamidase [Vibrio cholerae AM-19226]
Length = 206
Score = 122 bits (307), Expect = 1e-26, Method: Composition-based stats.
Identities = 73/194 (37%), Positives = 106/194 (54%), Gaps = 23/194 (11%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
K L++VD+QNDF SP G+L VP G+ ++ I+ L+ + ++ T+DWHP++H SFA
Sbjct: 3 KALLLVDVQNDF-SPSGALPVPDGDAIVPVINQLLPL----FEHVIATKDWHPAKHASFA 57
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGI---LWPVHCVKNTWGSQLVDQIMDQVVTKHIK 118
+ PG+ GI +WP HCV+NT G++ + + Q +T
Sbjct: 58 ------------SVQGKTPGEVIDLNGIPQVMWPDHCVQNTHGAEFIAGLDVQRITH--- 102
Query: 119 IVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAEL 178
IV KG D + YS F D FH T + +YL EVYI G+A +YCVK TA+ A L
Sbjct: 103 IVTKGTHPDVDSYSGFFDNQRFHATGLAEYLSNQGISEVYIAGLATDYCVKYTALDAVSL 162
Query: 179 GYKTTVLLDYTRPI 192
+KT V+ D R +
Sbjct: 163 YFKTWVIQDACRGV 176
>ref|YP_342331.1| Nicotinamidase [Nitrosococcus oceani ATCC 19707]
gb|ABA56801.1| Nicotinamidase [Nitrosococcus oceani ATCC 19707]
Length = 221
Score = 122 bits (306), Expect = 2e-26, Method: Composition-based stats.
Identities = 75/216 (34%), Positives = 118/216 (54%), Gaps = 20/216 (9%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L++VD+Q DF+ P G L V G ++I P+ LM+ +D+ H V T+DWHP H+SFA +
Sbjct: 15 LLLVDIQPDFL-PGGGLPVADGSQIIEPVRLLME-SDKFCH-YVATQDWHPPGHVSFASS 71
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
H EP +T + LWP HC++ T G++L + + V I+ KG
Sbjct: 72 HPGAEPMATLEING--------YAQTLWPDHCIQGTSGAELHGDLPWEKVAA---IIRKG 120
Query: 124 FLTDREYYSAFHDIWNFH----KTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELG 179
+ + YS FH+ WN T + YL + +E++I G+A + C+K TA A G
Sbjct: 121 TDPESDSYSGFHNNWNSAGERPATGLAGYLRERGIEELFICGLARDVCIKWTAEDGANAG 180
Query: 180 YKTTVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
+ VL D TRP+ +P ++V+ EL AH++ ++D
Sbjct: 181 FNVYVLWDLTRPV--EPSSDDQVRRELIAHDVKIID 214
>ref|XP_001559960.1| hypothetical protein BC1G_01519 [Botryotinia fuckeliana B05.10]
gb|EDN27249.1| hypothetical protein BC1G_01519 [Botryotinia fuckeliana B05.10]
Length = 231
Score = 122 bits (306), Expect = 2e-26, Method: Composition-based stats.
Identities = 75/196 (38%), Positives = 111/196 (56%), Gaps = 11/196 (5%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
LIVVD+Q DF+ P GSL V G + I I++L+ +H + T+DWHPS HISFA N
Sbjct: 13 LIVVDLQEDFLPPNGSLAVSNGRDTIPIINNLLT---LPFHLKIATKDWHPSNHISFASN 69
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
H K+P++ +T T + LWP HC+++T GS+ ++ K K + KG
Sbjct: 70 HAGKQPFADFTTIINPSNPSETYQVRLWPPHCIQDTLGSEFPFELD---TNKFTKTILKG 126
Query: 124 FLTDREYYSAFHD-IWNFHKTD--MNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
D E YSAF+D + N +D + +L+ VY+VG+A +YCVK TA +A G+
Sbjct: 127 QNPDVEMYSAFYDPLKNPRCSDSGLATHLKNEGITHVYVVGLAADYCVKCTAEDSATEGF 186
Query: 181 KTTVLLDYTRPISDDP 196
T ++ + TR + DP
Sbjct: 187 NTFIIEEGTRAV--DP 200
>ref|XP_001417004.1| predicted protein [Ostreococcus lucimarinus CCE9901]
gb|ABO95297.1| predicted protein [Ostreococcus lucimarinus CCE9901]
Length = 238
Score = 122 bits (305), Expect = 2e-26, Method: Composition-based stats.
Identities = 71/186 (38%), Positives = 99/186 (53%), Gaps = 15/186 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L+V+D+QNDF +P G+LTV G+ + S ++ DR +V +D+HP+ H SFA
Sbjct: 37 RALLVIDVQNDFAAPSGALTVRGGDGVARACSRCVEAFDR----VVFAQDYHPAGHESFA 92
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H K PY TQ LWP HCV+ TWG D D VV +V
Sbjct: 93 SAHAGKAPYDEVELAH------GTQ--TLWPDHCVQGTWGCAFHD---DLVVPARAMVVR 141
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG D + YSAF + T +++YL+K VY+VG+A ++CVK TA+ A LGY
Sbjct: 142 KGHNRDVDSYSAFFENDRRSDTGLDEYLKKEGVKRVYVVGLAYDFCVKYTALDAKRLGYD 201
Query: 182 TTVLLD 187
V+ D
Sbjct: 202 AYVVRD 207
>ref|XP_001218134.1| conserved hypothetical protein [Aspergillus terreus NIH2624]
gb|EAU29703.1| conserved hypothetical protein [Aspergillus terreus NIH2624]
Length = 238
Score = 121 bits (303), Expect = 4e-26, Method: Composition-based stats.
Identities = 77/227 (33%), Positives = 117/227 (51%), Gaps = 21/227 (9%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
LIVVDMQ DF P GSL V + + I+ L+ A+ + + T D+HP HISFA N
Sbjct: 5 LIVVDMQEDFCPPNGSLAVHEARSIAPTINTLL--ANPAFALRIATLDYHPPNHISFAPN 62
Query: 64 HK--DKEPYSTYTYHS-PRPG-DDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKI 119
H + P+ +Y + P P D T+ LWPVHCV+ T G++++ +I ++K
Sbjct: 63 HPAPNNRPFESYVIMTNPAPDKQDETKPQRLWPVHCVQGTKGAEMIPEIDASRFDLYVK- 121
Query: 120 VDKGFLTDREYYSAFHDIWNFHKT------------DMNKYLEKHHTDEVYIVGVALEYC 167
KG E YSAF D + KT D+ +L + +V++ GVA +YC
Sbjct: 122 --KGLHPQVEMYSAFADAFGNFKTAEGDDGGESVDIDLRTFLNDKNITDVFVTGVAGDYC 179
Query: 168 VKATAISAAELGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
VK T + A G+K+ + D TR + + +EEL+A +++V
Sbjct: 180 VKFTTMDAVRAGFKSYFVEDATRCTVPGKDCLEATREELRAAGVSIV 226
>ref|ZP_01908379.1| nicotinamidase/pyrazinamidase [Plesiocystis pacifica SIR-1]
gb|EDM78611.1| nicotinamidase/pyrazinamidase [Plesiocystis pacifica SIR-1]
Length = 221
Score = 120 bits (302), Expect = 6e-26, Method: Composition-based stats.
Identities = 73/212 (34%), Positives = 114/212 (53%), Gaps = 12/212 (5%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
LI+VD+Q DF+ P G+L VP+G+ ++ PI L+ DA D+ +V T+DWHP+ H SFA N
Sbjct: 7 LIIVDLQPDFL-PGGALAVPEGDAVLAPIRALL-DAG-DYATVVATQDWHPAEHRSFAAN 63
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
H ++ D + +LWPVHCV+++ G+ L ++ + + KG
Sbjct: 64 HDARQVGEVI--------DLDGLDQVLWPVHCVQDSPGAAL-HGALEARRGRLDAVFQKG 114
Query: 124 FLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTT 183
+ YS F D T + +L + + V++ G+AL+YCVK TA+ A ELG+ TT
Sbjct: 115 TELGVDSYSGFFDNGRRKATGLGDWLRERGVESVHVCGLALDYCVKFTALDALELGFATT 174
Query: 184 VLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
++ D TR ++ P L+ VVD
Sbjct: 175 LIADATRAVNLQPGDGEAAVTALREAGAQVVD 206
>ref|YP_001817930.1| Nicotinamidase [Opitutus terrae PB90-1]
gb|ACB74330.1| Nicotinamidase [Opitutus terrae PB90-1]
Length = 206
Score = 119 bits (299), Expect = 1e-25, Method: Composition-based stats.
Identities = 74/217 (34%), Positives = 115/217 (52%), Gaps = 23/217 (10%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M LI+VD+QNDF+ P G+L VP G+E++ + L+ DR + IV T+DWHP H SF
Sbjct: 1 MNALILVDIQNDFL-PGGALPVPHGDEVVAVANRLL---DR-FPVIVATQDWHPENHGSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEG---ILWPVHCVKNTWGSQLVDQIMDQVVTKHI 117
A N + PG + G ++WP HCV+NT G+ + + +
Sbjct: 56 AANRGQQ------------PGTMAELGGLPQVMWPNHCVQNTGGAAFAPGLNTARIQR-- 101
Query: 118 KIVDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAE 177
+ KG + + YS F D T + YL V+++G+A +YCVKATAI A +
Sbjct: 102 -VFPKGTGPEIDSYSGFFDNRRRKATGLGDYLTLKGVTHVFVLGLATDYCVKATAIDAQQ 160
Query: 178 LGYKTTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
LG+ TT++LD R + +P ++ EE++ + +V
Sbjct: 161 LGFTTTLVLDGCRGVELNPGDCDRALEEMQRAGVRLV 197
>ref|ZP_03965982.1| nicotinamidase [Sphingobacterium spiritivorum ATCC 33300]
gb|EEI94191.1| nicotinamidase [Sphingobacterium spiritivorum ATCC 33300]
Length = 196
Score = 119 bits (298), Expect = 1e-25, Method: Composition-based stats.
Identities = 77/208 (37%), Positives = 106/208 (50%), Gaps = 20/208 (9%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
MK LI+VD+QNDF+ P GSL V G+E+I I+ L D + IV T+DWHP H SF
Sbjct: 1 MKALIIVDVQNDFL-PGGSLAVEHGDEIIPLINGLQSD----YGLIVATQDWHPVHHKSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQI-MDQVVTKHIKI 119
A H K + + E LWP HCV+ + G+ +Q+ MD+V +
Sbjct: 56 AAEHPGKSLFEVIELNG--------LEQRLWPTHCVQGSSGAAFHEQLDMDRVEA----V 103
Query: 120 VDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELG 179
KG + + YS F D T + YL +EV+I G+A +YCV TA A LG
Sbjct: 104 FRKGMDAEIDSYSGFFDNGRRKNTGLAGYLRDRTIEEVHICGLAADYCVYFTAKDALSLG 163
Query: 180 YKTTVLLDYTRPISDDPEVINKVKEELK 207
+KT +L D T+ I DP K+ +
Sbjct: 164 FKTAILTDATKAI--DPAQFEKLARSFE 189
>ref|ZP_01094319.1| pyrazinamidase/nicotinamidase [Blastopirellula marina DSM 3645]
gb|EAQ76976.1| pyrazinamidase/nicotinamidase [Blastopirellula marina DSM 3645]
Length = 205
Score = 119 bits (297), Expect = 2e-25, Method: Composition-based stats.
Identities = 69/215 (32%), Positives = 116/215 (53%), Gaps = 18/215 (8%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M+ L+++D+QNDF+ P GSL V +G+++I I+ + R + +V T+DWHP H SF
Sbjct: 1 MRALLLIDVQNDFL-PGGSLAVAEGDQIIPIINACL----RKFDLVVATKDWHPPEHESF 55
Query: 61 AKNHKDKEPYSTYTYHS-PRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKI 119
A H H P+ ILWP HCV+++ GS+ D + + +
Sbjct: 56 ASQHVGHAVGQQIDLHGLPQ---------ILWPDHCVQHSRGSEFSDDLQTAAIDH---V 103
Query: 120 VDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELG 179
+ KG + YS F D H T ++ +L+ E+YI G+A +YC+K TA+ A +LG
Sbjct: 104 IYKGDDPQIDSYSGFFDNDRRHATGLHAWLQAKGVTELYIAGLATDYCIKYTALDAIDLG 163
Query: 180 YKTTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
Y+ +++D R + P +N +E++AH + ++
Sbjct: 164 YRVQLIVDACRGVDLSPGDVNAALKEMEAHGVKLI 198
>ref|YP_001899019.1| Nicotinamidase [Ralstonia pickettii 12J]
gb|ACD26587.1| Nicotinamidase [Ralstonia pickettii 12J]
Length = 213
Score = 118 bits (295), Expect = 3e-25, Method: Composition-based stats.
Identities = 68/189 (35%), Positives = 106/189 (56%), Gaps = 13/189 (6%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+++D+QNDF+ P G+L VP G+++I P+ +L+ A R V+T+DWHPS H+SFA N
Sbjct: 9 LLIIDVQNDFL-PGGALAVPDGDQVI-PVVNLLAKAFGAVGRTVLTQDWHPSEHVSFAAN 66
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
H +P+ T D + +LWPVHCV+++ G+ L D + V IV KG
Sbjct: 67 HPGTQPFGTI--------DLPYGQQVLWPVHCVQHSKGAALADGLN---VPHAQLIVRKG 115
Query: 124 FLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTT 183
+ + YSAF + T + YL + + V+ VG+A ++CV +A+ A G +
Sbjct: 116 YHPHIDSYSAFFEADRKTPTGLLGYLRELGVERVFCVGLATDFCVAWSALDARAAGLEVV 175
Query: 184 VLLDYTRPI 192
V+ D R I
Sbjct: 176 VIEDACRAI 184
>ref|ZP_01756653.1| pyrazinamidase/nicotinamidase [Roseobacter sp. SK209-2-6]
gb|EBA14615.1| pyrazinamidase/nicotinamidase [Roseobacter sp. SK209-2-6]
Length = 198
Score = 118 bits (295), Expect = 4e-25, Method: Composition-based stats.
Identities = 69/191 (36%), Positives = 101/191 (52%), Gaps = 17/191 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+TLIV+D+QNDF P G+L VP G+E++ PI+ +M D D +V+T+DWHP H SFA
Sbjct: 3 ETLIVIDVQNDF-CPGGALAVPGGDEVVAPINAMMADFD----AVVLTQDWHPHGHSSFA 57
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H+ K P+ T S +LWP HCV+ G+ + Q I+
Sbjct: 58 ASHEGKAPFETIEL--------SYGTQVLWPEHCVQGEKGADFHGDLNTQADL----IIR 105
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + YSAF + T + YL ++ + G+A ++CV +A+ AA LG+
Sbjct: 106 KGFRPAIDSYSAFFENDQKTPTGLEGYLRDRGLQKLTLAGLATDFCVAFSALDAARLGFD 165
Query: 182 TTVLLDYTRPI 192
TV L R I
Sbjct: 166 VTVALSACRAI 176
>ref|NP_142913.1| pyrazinamidase/nicotinamidase [Pyrococcus horikoshii OT3]
pdb|1IM5|A Chain A, Crystal Structure Of Pyrazinamidase Of Pyrococcus
Horikoshii In Complex With Zinc
pdb|1ILW|A Chain A, Crystal Structure Of PyrazinamidaseNICOTINAMIDASE OF
Pyrococcus Horikoshii
dbj|BAA30096.1| 180aa long hypothetical pyrazinamidase/nicotinamidase [Pyrococcus
horikoshii OT3]
Length = 180
Score = 117 bits (294), Expect = 5e-25, Method: Composition-based stats.
Identities = 75/213 (35%), Positives = 108/213 (50%), Gaps = 38/213 (17%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ LIVVDMQ DF+ P G+L VP+G+++I +++ ++ IV TRDWHP HISF
Sbjct: 4 EALIVVDMQRDFM-PGGALPVPEGDKIIPKVNEYIRKFKEKGALIVATRDWHPENHISF- 61
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+ G WP HCV+NT G++ V + + V I+
Sbjct: 62 -----------------------RERGGPWPRHCVQNTPGAEFVVDLPEDAV-----IIS 93
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
K D+E YS F TD+ K L + VYI GVA EYCV+ATA+ A + G++
Sbjct: 94 KATEPDKEAYSGFEG------TDLAKILRGNGVKRVYICGVATEYCVRATALDALKHGFE 147
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
+L D + I PE + EE+K+ I +V
Sbjct: 148 VYLLRDAVKGIK--PEDEERALEEMKSRGIKIV 178
>ref|ZP_01745842.1| pyrazinamidase/nicotinamidase [Sagittula stellata E-37]
gb|EBA08464.1| pyrazinamidase/nicotinamidase [Sagittula stellata E-37]
Length = 197
Score = 117 bits (293), Expect = 6e-25, Method: Composition-based stats.
Identities = 68/196 (34%), Positives = 106/196 (54%), Gaps = 18/196 (9%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M LIV+D+QNDF P G+L V +G+E++ PI+ LM + D +V+T+DWHP+ H SF
Sbjct: 1 MHALIVIDVQNDF-CPGGALAVAQGDEIVQPINALMAEFDA----VVLTQDWHPAGHSSF 55
Query: 61 AKNHKDKEPYSTYTY-HSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKI 119
A H+ K P+ + P+ +LWP HC++ + G+ M+ + I
Sbjct: 56 ASAHEGKAPFEMIDMPYGPQ---------VLWPDHCIQASPGANFH---MELETDRADLI 103
Query: 120 VDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELG 179
+ KGF + + YSAF + + T + YL D + +VG+A ++CV +A+ AA LG
Sbjct: 104 IRKGFRSAIDSYSAFFENDHTTPTGLEGYLRTRGIDRLTLVGLATDFCVNYSAVDAARLG 163
Query: 180 YKTTVLLDYTRPISDD 195
+ V D R I D
Sbjct: 164 FSVAVREDLCRAIDLD 179
>ref|YP_001006490.1| nicotinamidase/pyrazinamidase [Yersinia enterocolitica subsp.
enterocolitica 8081]
emb|CAL12322.1| putative pyrazinamidase/nicotinamidase [Yersinia enterocolitica
subsp. enterocolitica 8081]
Length = 217
Score = 117 bits (293), Expect = 6e-25, Method: Composition-based stats.
Identities = 67/194 (34%), Positives = 113/194 (58%), Gaps = 13/194 (6%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+++D+QNDF P G+L V KG+ +I ++ + I+ ++DWHP+ H SFA N
Sbjct: 5 LLLIDLQNDF-CPGGALAVAKGDAVIAVANEAITTCLAHKIPIIASQDWHPAEHRSFAVN 63
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
+ EP++T GD + WPVHCV+N+ G+ L ++ +V+T+ I KG
Sbjct: 64 SQ-AEPWTT--------GDLEGLTQVWWPVHCVQNSVGAALHPKLNQEVITQ---IFRKG 111
Query: 124 FLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTT 183
D + YSAF D KT ++ +L++ + ++++G+A +YCVK T ++A LGYKT+
Sbjct: 112 QNPDIDSYSAFFDNGRRAKTPLDDWLQQQGINCLFVMGLATDYCVKYTVLAALTLGYKTS 171
Query: 184 VLLDYTRPISDDPE 197
V+ D ++ P+
Sbjct: 172 VIKDGCHGVNLQPQ 185
>ref|YP_001400957.1| pyrazinamidase/nicotinamidase [Yersinia pseudotuberculosis IP
31758]
gb|ABS48137.1| pyrazinamidase/nicotinamidase [Yersinia pseudotuberculosis IP
31758]
Length = 215
Score = 116 bits (291), Expect = 9e-25, Method: Composition-based stats.
Identities = 67/197 (34%), Positives = 108/197 (54%), Gaps = 19/197 (9%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+++D+QNDF P G+L V +G+E+I+ + +++ ++ ++DWHP H SFA N
Sbjct: 5 LLLIDLQNDF-CPGGALAVSEGDEVISVANRMIEACLAKNIPVIASQDWHPIEHRSFAVN 63
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGIL---WPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
K PG EG++ WPVHCV+ G+ L Q+ +T I
Sbjct: 64 AK------------AEPGTVGELEGLVQVWWPVHCVQEQPGAALHPQLKQGAITA---IF 108
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KG D + YS F D KT ++ +L++H D +Y++G+A +YCVK + + A LGY
Sbjct: 109 RKGQNPDIDSYSTFFDNGRRSKTALDSWLQQHSIDHLYVMGLATDYCVKYSVLDALALGY 168
Query: 181 KTTVLLDYTRPISDDPE 197
+TTV+ D R ++ P+
Sbjct: 169 QTTVISDGCRGVNLQPQ 185
>ref|XP_001912686.1| unnamed protein product [Podospora anserina]
emb|CAP60168.1| unnamed protein product [Podospora anserina]
Length = 240
Score = 116 bits (291), Expect = 9e-25, Method: Composition-based stats.
Identities = 75/215 (34%), Positives = 114/215 (53%), Gaps = 17/215 (7%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+VVDMQ DF P GSL VP G + I+ L+ R + T+DWHP HISFA N
Sbjct: 12 LLVVDMQEDFCPPSGSLAVPLGRTITPLINTLLTLPPRTLPLKIATQDWHPPNHISFAPN 71
Query: 64 HKDKEP--YSTYTYHSP-RPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
H P +++T +P P T +LWP HC+++T G+ L+ ++ Q T I+
Sbjct: 72 HPSNPPPFVTSHTITNPLNPSQSYTT--LLWPPHCIQSTPGASLIPELSSQNFT---HII 126
Query: 121 DKGFLTDREYYSAFHDIW-------NFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAI 173
KG E YSAF D + + + K L VY+VG+A +YCVK TA
Sbjct: 127 KKGLDPRVEMYSAFFDPFPPTLTGERVCDSGLAKLLHDEKVTHVYVVGLAGDYCVKHTAY 186
Query: 174 SAAELGYKTTVLLDYTRPISDDPEVINKVKEELKA 208
AA+ G++T ++ + T+ + +P + K+E+++
Sbjct: 187 DAAKEGFQTVIIEEGTKTV--NPGGWEECKKEMES 219
>ref|YP_070603.1| nicotinamidase/pyrazinamidase [Yersinia pseudotuberculosis IP
32953]
ref|YP_001720832.1| Nicotinamidase [Yersinia pseudotuberculosis YPIII]
ref|YP_001872569.1| isochorismatase hydrolase [Yersinia pseudotuberculosis PB1/+]
emb|CAH21324.1| putative pyrazinamidase/nicotinamidase [Yersinia pseudotuberculosis
IP 32953]
gb|ACA68379.1| Nicotinamidase [Yersinia pseudotuberculosis YPIII]
gb|ACC89112.1| isochorismatase hydrolase [Yersinia pseudotuberculosis PB1/+]
Length = 215
Score = 116 bits (291), Expect = 1e-24, Method: Composition-based stats.
Identities = 67/197 (34%), Positives = 108/197 (54%), Gaps = 19/197 (9%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+++D+QNDF P G+L V +G+E+I+ + +++ ++ ++DWHP H SFA N
Sbjct: 5 LLLIDLQNDF-CPGGALAVSEGDEVISVANRMIEACLAKNIPVIASQDWHPIEHRSFAVN 63
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGIL---WPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
K PG EG++ WPVHCV+ G+ L Q+ +T I
Sbjct: 64 AK------------AEPGTVGELEGLVQVWWPVHCVQEQPGAALHPQLKQGAITA---IF 108
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KG D + YS F D KT ++ +L++H D +Y++G+A +YCVK + + A LGY
Sbjct: 109 RKGQNPDIDSYSTFFDNGRRAKTALDSWLQQHSIDHLYVMGLATDYCVKYSVLDALALGY 168
Query: 181 KTTVLLDYTRPISDDPE 197
+TTV+ D R ++ P+
Sbjct: 169 QTTVISDGCRGVNLQPQ 185
>ref|NP_405705.1| nicotinamidase/pyrazinamidase [Yersinia pestis CO92]
ref|NP_669473.1| nicotinamidase/pyrazinamidase [Yersinia pestis KIM]
ref|NP_993300.1| nicotinamidase/pyrazinamidase [Yersinia pestis biovar Microtus str.
91001]
ref|YP_651429.1| nicotinamidase/pyrazinamidase [Yersinia pestis Antiqua]
ref|YP_647556.1| nicotinamidase/pyrazinamidase [Yersinia pestis Nepal516]
ref|YP_001162347.1| nicotinamidase/pyrazinamidase [Yersinia pestis Pestoides F]
ref|ZP_01887952.1| putative pyrazinamidase/nicotinamidase [Yersinia pestis CA88-4125]
ref|YP_001606777.1| pyrazinamidase/nicotinamidase [Yersinia pestis Angola]
ref|ZP_02223525.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Orientalis
str. F1991016]
ref|ZP_02227889.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Orientalis
str. IP275]
ref|ZP_02230211.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Antiqua str.
E1979001]
ref|ZP_02237175.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Antiqua str.
B42003004]
ref|ZP_02306876.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Antiqua str.
UG05-0454]
ref|ZP_02312026.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Orientalis
str. MG05-1020]
ref|ZP_02318320.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Mediaevalis
str. K1973002]
ref|ZP_02335335.1| pyrazinamidase/nicotinamidase [Yersinia pestis FV-1]
gb|AAM85724.1|AE013819_10 hypothetical protein y2162 [Yersinia pestis KIM]
gb|AAS62177.1| putative pyrazinamidase/nicotinamidase [Yersinia pestis biovar
Microtus str. 91001]
gb|ABG17956.1| pyrazinamidase/nicotinamidase [Yersinia pestis Nepal516]
gb|ABG13484.1| putative pyrazinamidase/nicotinamidase [Yersinia pestis Antiqua]
emb|CAL20791.1| putative pyrazinamidase/nicotinamidase [Yersinia pestis CO92]
gb|ABP39374.1| pyrazinamidase/nicotinamidase [Yersinia pestis Pestoides F]
gb|EDM42404.1| putative pyrazinamidase/nicotinamidase [Yersinia pestis CA88-4125]
gb|ABX85429.1| pyrazinamidase/nicotinamidase [Yersinia pestis Angola]
gb|EDR31311.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Orientalis
str. IP275]
gb|EDR37584.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Orientalis
str. F1991016]
gb|EDR44169.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Antiqua str.
E1979001]
gb|EDR52800.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Antiqua str.
B42003004]
gb|EDR57989.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Orientalis
str. MG05-1020]
gb|EDR60483.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Antiqua str.
UG05-0454]
gb|EDR64255.1| pyrazinamidase/nicotinamidase [Yersinia pestis biovar Mediaevalis
str. K1973002]
Length = 215
Score = 116 bits (290), Expect = 1e-24, Method: Composition-based stats.
Identities = 67/197 (34%), Positives = 108/197 (54%), Gaps = 19/197 (9%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+++D+QNDF P G+L V +G+E+I+ + +++ ++ ++DWHP H SFA N
Sbjct: 5 LLLIDLQNDF-CPGGALAVSEGDEVISVANRMIEACLAKNIPVIASQDWHPIEHRSFAVN 63
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGIL---WPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
K PG EG++ WPVHCV+ G+ L Q+ +T I
Sbjct: 64 AK------------AEPGTVGELEGLVQVWWPVHCVQEQPGAALHPQLKQGAITA---IF 108
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KG D + YS F D KT ++ +L++H D +Y++G+A +YCVK + + A LGY
Sbjct: 109 RKGQNPDIDSYSTFFDNGRRAKTALDSWLQQHSIDHLYVMGLATDYCVKYSVLDALALGY 168
Query: 181 KTTVLLDYTRPISDDPE 197
+TTV+ D R ++ P+
Sbjct: 169 QTTVISDGCRGVNLQPQ 185
>ref|ZP_03850627.1| Nicotinamidase [Chryseobacterium gleum ATCC 35910]
gb|EEI44755.1| Nicotinamidase [Chryseobacterium gleum ATCC 35910]
Length = 201
Score = 116 bits (290), Expect = 1e-24, Method: Composition-based stats.
Identities = 73/196 (37%), Positives = 110/196 (56%), Gaps = 15/196 (7%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
K LI+VD+QNDF G+L VP E+I I+ LM++ + D +IV+T+DWHP+ H SFA
Sbjct: 3 KALIIVDVQNDFCEG-GALAVPGASEIIPYINLLMEENEYD--QIVLTQDWHPAGHKSFA 59
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
++ K S P+ +WP HC++ T+G++ + VT IV
Sbjct: 60 SSNGRKVGESIILNGVPQ---------FMWPDHCIQGTFGAEFHKDLNRDKVTH---IVQ 107
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + + YS F D +F KT ++ +L+ H V IVG+AL+YCVK TA+ A GY
Sbjct: 108 KGKNIEIDSYSGFQDNNHFMKTGLDDFLKYHDIQLVEIVGLALDYCVKFTALDAVANGYV 167
Query: 182 TTVLLDYTRPISDDPE 197
T + + TR ++ P+
Sbjct: 168 TCLHFNGTRAVNVKPD 183
>ref|ZP_00710421.1| COG1335: Amidases related to nicotinamidase [Escherichia coli B171]
Length = 219
Score = 116 bits (290), Expect = 1e-24, Method: Composition-based stats.
Identities = 66/196 (33%), Positives = 105/196 (53%), Gaps = 13/196 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCAG-GALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY PG WPVHCV+N+ G+QL + + + +
Sbjct: 69 SQHC-VEPY--------MPGQLDGLPQTFWPVHCVQNSEGAQLHPLLNQKAIAA---MFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPE 197
V+ D R ++ P+
Sbjct: 177 VNVITDGCRGVNIQPQ 192
>ref|ZP_02152324.1| pyrazinamidase/nicotinamidase [Oceanibulbus indolifex HEL-45]
gb|EDQ06191.1| pyrazinamidase/nicotinamidase [Oceanibulbus indolifex HEL-45]
Length = 198
Score = 116 bits (290), Expect = 1e-24, Method: Composition-based stats.
Identities = 70/211 (33%), Positives = 116/211 (54%), Gaps = 19/211 (9%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
LIV+D+QNDF P G+L VP+G+E++ I+ LM + + +V+T+DWHP+ H SFA +
Sbjct: 5 LIVIDVQNDF-CPGGALEVPQGDEILRGINALMPE----FAAVVLTQDWHPAGHSSFASS 59
Query: 64 HKDKEPYSTYTY-HSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
H PY T + P+ +LWP HC++ + G+Q D + I+ K
Sbjct: 60 HDGNAPYEIVTMPYGPQ---------VLWPDHCIQGSIGAQFHP---DLQTDRADLIIRK 107
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G+ D + YSAF + + T + YL + + +VG+AL++CV +A+ AA+LG+
Sbjct: 108 GYSPDIDSYSAFFENDHSTPTGLEGYLRTRGIERLTMVGLALDFCVNFSAVDAAKLGFNV 167
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V + R I D + K +E ++A + +
Sbjct: 168 DVREELCRAIDLDGS-LAKSREGMRAAGVTL 197
>ref|YP_222148.1| PncA, pyrazinamidase/nicotinamidase [Brucella abortus biovar 1 str.
9-941]
ref|YP_414852.1| Isochorismatase hydrolase family [Brucella melitensis biovar
Abortus 2308]
ref|YP_001935354.1| Isochorismatase hydrolase family [Brucella abortus S19]
gb|AAX74787.1| PncA, pyrazinamidase/nicotinamidase [Brucella abortus biovar 1 str.
9-941]
emb|CAJ11440.1| Isochorismatase hydrolase family [Brucella melitensis biovar
Abortus 2308]
gb|ACD72880.1| Isochorismatase hydrolase family [Brucella abortus S19]
Length = 209
Score = 115 bits (289), Expect = 1e-24, Method: Composition-based stats.
Identities = 69/214 (32%), Positives = 121/214 (56%), Gaps = 19/214 (8%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+V+D+QNDF P G+L V +G+E+I ++ L+ ++++ +VVT+DWHP+ H SFA N
Sbjct: 6 LVVIDVQNDF-CPGGALAVERGDEIIPIVNRLIGESEK----VVVTQDWHPANHSSFASN 60
Query: 64 HKDKEPYSTYTY-HSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
H P+ T + P+ +LWP HCV+N+ G++ D + +V K
Sbjct: 61 HSGSRPFDTVNMSYGPQ---------VLWPDHCVQNSEGAEFHP---DLQWWRAQLVVRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF + YSAF + + T + YL + + + +VG+A ++CV ++A+ A + G++
Sbjct: 109 GFRIGIDSYSAFFENDHCTPTGLGGYLRERNIGSLTMVGLATDFCVASSALDAVQQGFQV 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I D +N + E++K + ++D+
Sbjct: 169 RVRLDACRGI-DLNGSMNIMLEKMKQAGVELIDE 201
>ref|NP_105653.1| pyrazinamidase/nicotinamidase [Mesorhizobium loti MAFF303099]
dbj|BAB51439.1| pyrazinamidase/nicotinamidase [Mesorhizobium loti MAFF303099]
Length = 204
Score = 115 bits (288), Expect = 2e-24, Method: Composition-based stats.
Identities = 67/191 (35%), Positives = 106/191 (55%), Gaps = 16/191 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L+V+D+QNDF P G+L V G+E++ ++D+++ D +V+T+DWHP+ H SFA
Sbjct: 4 QALVVIDLQNDF-CPGGALAVTGGDEIVPLVNDMIRRTDH----VVLTQDWHPAGHSSFA 58
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H +P++ P T LWP HC++ + GS + TK ++
Sbjct: 59 SSHPGAQPFTMIEM----PYGQQT----LWPDHCIQGSLGSDFHSGL---AWTKAELVIR 107
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF D + YSAF + + T + YL + D V +VG+A ++CV +A+ A G+K
Sbjct: 108 KGFRPDIDSYSAFFENDHTTPTGLGGYLRERGIDTVTLVGLATDFCVGFSALDAVSQGFK 167
Query: 182 TTVLLDYTRPI 192
TTV LD R I
Sbjct: 168 TTVRLDACRGI 178
>ref|YP_001743481.1| pyrazinamidase/nicotinamidase [Escherichia coli SMS-3-5]
gb|ACB19609.1| pyrazinamidase/nicotinamidase [Escherichia coli SMS-3-5]
Length = 213
Score = 115 bits (288), Expect = 2e-24, Method: Composition-based stats.
Identities = 66/196 (33%), Positives = 105/196 (53%), Gaps = 13/196 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCAG-GALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLKQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ I+G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTALDDWLRDHEIDELIIMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPE 197
V+ D R ++ P+
Sbjct: 171 VNVITDGCRGVNIQPQ 186
>ref|ZP_02826083.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str. EC508]
Length = 213
Score = 115 bits (288), Expect = 2e-24, Method: Composition-based stats.
Identities = 65/196 (33%), Positives = 105/196 (53%), Gaps = 13/196 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCAG-GALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPE 197
V+ D R ++ P+
Sbjct: 171 VNVITDGCRGVNIQPQ 186
>gb|AAZ88098.1| conserved hypothetical protein [Shigella sonnei Ss046]
Length = 219
Score = 115 bits (287), Expect = 2e-24, Method: Composition-based stats.
Identities = 65/196 (33%), Positives = 105/196 (53%), Gaps = 13/196 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCAG-GALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPE 197
V+ D R ++ P+
Sbjct: 177 VNVITDGCRGVNIQPQ 192
>gb|AAG56755.1|AE005399_9 orf, hypothetical protein [Escherichia coli O157:H7 EDL933]
dbj|BAB35898.1| hypothetical protein [Escherichia coli O157:H7 str. Sakai]
Length = 219
Score = 115 bits (287), Expect = 3e-24, Method: Composition-based stats.
Identities = 65/196 (33%), Positives = 105/196 (53%), Gaps = 13/196 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCAG-GALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPE 197
V+ D R ++ P+
Sbjct: 177 VNVITDGCRGVNIQPQ 192
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|NP_011478.1| Nicotinamidase that converts nicotinamide ... 319 8e-86
ref|XP_444840.1| hypothetical protein CAGL0A01716g [Candida... 269 1e-70
ref|YP_002824764.1| pyrazinamidase/nicotinamidase [Rhizobiu... 268 2e-70
ref|NP_539463.1| PYRAZINAMIDASE / NICOTINAMIDASE [Brucella ... 266 6e-70
ref|YP_222148.1| PncA, pyrazinamidase/nicotinamidase [Bruce... 266 7e-70
ref|YP_001593297.1| Nicotinamidase [Brucella canis ATCC 233... 264 2e-69
ref|YP_001628120.1| Nicotinamidase [Brucella suis ATCC 2344... 264 3e-69
ref|ZP_01853806.1| pyrazinamidase/nicotinamidase [Planctomy... 264 3e-69
ref|YP_611664.1| Nicotinamidase [Silicibacter sp. TM1040] >... 264 4e-69
ref|NP_384685.1| PROBABLE PYRAZINAMIDASE/NICOTINAMIDASE (IN... 263 4e-69
ref|NP_698460.1| pyrazinamidase/nicotinamidase [Brucella su... 263 4e-69
gb|AAG56755.1|AE005399_9 orf, hypothetical protein [Escheri... 263 7e-69
ref|YP_445581.1| pyrazinamidase/nicotinamidase [Salinibacte... 263 7e-69
ref|ZP_00714471.1| COG1335: Amidases related to nicotinamid... 263 7e-69
gb|AAZ88098.1| conserved hypothetical protein [Shigella son... 263 7e-69
ref|ZP_02826083.1| pyrazinamidase/nicotinamidase [Escherich... 263 9e-69
ref|YP_001325893.1| Nicotinamidase [Sinorhizobium medicae W... 262 9e-69
gb|ABB61643.1| conserved hypothetical protein [Shigella dys... 262 1e-68
ref|NP_288202.2| nicotinamidase/pyrazinamidase [Escherichia... 262 1e-68
ref|YP_407774.2| nicotinamidase/pyrazinamidase [Shigella bo... 262 1e-68
ref|ZP_00924703.1| COG1335: Amidases related to nicotinamid... 262 1e-68
ref|YP_403134.2| nicotinamidase/pyrazinamidase [Shigella dy... 262 1e-68
ref|ZP_00720836.1| COG1335: Amidases related to nicotinamid... 262 2e-68
ref|AP_002387.1| nicotinamidase/pyrazinamidase [Escherichia... 262 2e-68
ref|YP_675744.1| isochorismatase hydrolase [Mesorhizobium s... 262 2e-68
ref|ZP_00710421.1| COG1335: Amidases related to nicotinamid... 262 2e-68
gb|AAN43052.1| orf, conserved hypothetical protein [Shigell... 261 2e-68
ref|ZP_00921076.1| COG1335: Amidases related to nicotinamid... 261 2e-68
ref|YP_001463067.1| pyrazinamidase/nicotinamidase [Escheric... 261 2e-68
ref|YP_688945.1| nicotinamidase/pyrazinamidase [Shigella fl... 261 3e-68
ref|YP_001743481.1| pyrazinamidase/nicotinamidase [Escheric... 261 3e-68
ref|ZP_00999691.1| pyrazinamidase/nicotinamidase [Oceanicol... 261 3e-68
ref|ZP_01745842.1| pyrazinamidase/nicotinamidase [Sagittula... 261 3e-68
ref|NP_105653.1| pyrazinamidase/nicotinamidase [Mesorhizobi... 260 4e-68
ref|ZP_02152324.1| pyrazinamidase/nicotinamidase [Oceanibul... 260 6e-68
ref|ZP_02742886.1| nicotinamidase/pyrazinamidase [Escherich... 259 9e-68
ref|ZP_01443288.1| pyrazinamidase/nicotinamidase [Roseovari... 259 1e-67
ref|ZP_00725208.1| COG1335: Amidases related to nicotinamid... 259 1e-67
ref|YP_584002.1| isochorismatase hydrolase [Ralstonia metal... 258 1e-67
ref|YP_001534681.1| Nicotinamidase [Dinoroseobacter shibae ... 258 2e-67
ref|YP_669620.1| nicotinamidase/pyrazinamidase [Escherichia... 258 2e-67
ref|ZP_02813180.1| nicotinamidase/pyrazinamidase [Escherich... 258 2e-67
ref|YP_001259350.1| pyrazinamidase/nicotinamidase [Brucella... 258 2e-67
ref|ZP_01015636.1| pyrazinamidase/nicotinamidase [Rhodobact... 257 3e-67
ref|YP_001453362.1| hypothetical protein CKO_01797 [Citroba... 257 5e-67
ref|ZP_01877931.1| Nicotinamidase [Roseovarius sp. TM1035] ... 256 6e-67
ref|ZP_01055578.1| pyrazinamidase/nicotinamidase [Roseobact... 256 9e-67
ref|ZP_01756653.1| pyrazinamidase/nicotinamidase [Roseobact... 256 9e-67
ref|YP_001370254.1| Nicotinamidase [Ochrobactrum anthropi A... 255 2e-66
ref|ZP_00954335.1| pyrazinamidase/nicotinamidase [Sulfitoba... 254 2e-66
ref|ZP_01902192.1| pyrazinamidase/nicotinamidase [Roseobact... 254 3e-66
ref|ZP_02295815.1| Nicotinamidase [Rhizobium leguminosarum ... 254 3e-66
ref|YP_348618.1| Nicotinamidase [Pseudomonas fluorescens Pf... 254 3e-66
ref|YP_001712055.1| bifunctional protein [Includes: pyrazin... 253 4e-66
ref|YP_001708611.1| bifunctional protein [Includes: pyrazin... 253 4e-66
ref|ZP_00948880.1| pyrazinamidase/nicotinamidase [Sulfitoba... 253 5e-66
ref|ZP_01154749.1| pyrazinamidase/nicotinamidase [Oceanicol... 253 6e-66
ref|ZP_01127503.1| Nicotinamidase [Nitrococcus mobilis Nb-2... 253 7e-66
ref|YP_001848274.1| Amidase related to nicotinamidase [Acin... 253 8e-66
ref|YP_094325.1| bifunctional pyrazinamidase/nicotinamidase... 252 1e-65
ref|ZP_03823780.1| nicotinamidase-like amidase [Acinetobact... 252 1e-65
ref|YP_001438252.1| hypothetical protein ESA_02167 [Enterob... 252 1e-65
ref|YP_001570719.1| hypothetical protein SARI_01686 [Salmon... 252 1e-65
ref|YP_507956.1| Nicotinamidase [Jannaschia sp. CCS1] >gi|8... 252 1e-65
ref|YP_354449.1| probable pyrazinamidase/nicotinamidase [Rh... 252 1e-65
ref|ZP_02965199.1| isochorismatase hydrolase [bacterium Ell... 252 1e-65
ref|ZP_00833121.1| COG1335: Amidases related to nicotinamid... 252 1e-65
ref|YP_048046.1| bifunctional protein [Includes: pyrazinami... 252 2e-65
ref|ZP_02061772.1| pyrazinamidase/nicotinamidase (PZAase)(N... 252 2e-65
ref|YP_001249688.1| bifunctional pyrazinamidase/nicotinamid... 252 2e-65
ref|ZP_00829124.1| COG1335: Amidases related to nicotinamid... 252 2e-65
ref|YP_001609939.1| pyrazinamidase/nicotinamidase [Bartonel... 251 2e-65
ref|YP_165367.1| pyrazinamidase/nicotinamidase [Silicibacte... 251 3e-65
ref|YP_001041928.1| Nicotinamidase [Rhodobacter sphaeroides... 251 3e-65
ref|YP_470316.1| pyrazinamidase/nicotinamidase protein [Rhi... 251 3e-65
ref|YP_001176409.1| nicotinamidase/pyrazinamidase [Enteroba... 250 4e-65
ref|YP_768860.1| putative pyrazinamidase/nicotinamidase [Rh... 250 4e-65
ref|ZP_01094319.1| pyrazinamidase/nicotinamidase [Blastopir... 250 4e-65
ref|XP_456073.1| unnamed protein product [Kluyveromyces lac... 250 4e-65
ref|ZP_02362493.1| pyrazinamidase/nicotinamidase [Burkholde... 250 4e-65
ref|YP_001641346.1| Nicotinamidase [Methylobacterium extorq... 250 4e-65
ref|YP_001006490.1| nicotinamidase/pyrazinamidase [Yersinia... 250 5e-65
ref|ZP_02355353.1| pyrazinamidase/nicotinamidase [Burkholde... 250 5e-65
ref|ZP_01002009.1| pyrazinamidase/nicotinamidase [Loktanell... 250 6e-65
ref|ZP_02146752.1| Nicotinamidase [Phaeobacter gallaeciensi... 250 6e-65
ref|ZP_00820544.1| COG1335: Amidases related to nicotinamid... 250 7e-65
ref|ZP_02346109.1| nicotinamidase/pyrazinamidase [Salmonell... 249 8e-65
ref|ZP_01035501.1| pyrazinamidase/nicotinamidase [Roseovari... 249 8e-65
ref|YP_001857264.1| Nicotinamidase [Burkholderia phymatum S... 249 8e-65
ref|YP_001588271.1| hypothetical protein SPAB_02051 [Salmon... 249 8e-65
ref|ZP_02669331.1| nicotinamidase/pyrazinamidase [Salmonell... 249 9e-65
ref|NP_460259.1| nicotinamidase/pyrazinamidase [Salmonella ... 249 9e-65
ref|YP_995658.1| Nicotinamidase [Verminephrobacter eiseniae... 249 9e-65
ref|YP_001817930.1| Nicotinamidase [Opitutus terrae PB90-1]... 249 1e-64
ref|YP_032511.1| Pyrazinamidase /nicotinamidase pnca [Barto... 249 1e-64
ref|ZP_00959572.1| pyrazinamidase/nicotinamidase [Roseovari... 249 1e-64
ref|NP_456219.1| nicotinamidase/pyrazinamidase [Salmonella ... 249 1e-64
ref|YP_001238488.1| nicotinamidase/pyrazinamidase [Bradyrhi... 249 1e-64
ref|YP_989240.1| isochorismatase family protein [Bartonella... 249 1e-64
ref|ZP_00050215.2| COG1335: Amidases related to nicotinamid... 248 1e-64
ref|YP_295620.1| Nicotinamidase [Ralstonia eutropha JMP134]... 248 1e-64
ref|YP_001478953.1| Nicotinamidase [Serratia proteamaculans... 248 1e-64
ref|ZP_02568027.1| nicotinamidase/pyrazinamidase [Salmonell... 248 2e-64
ref|ZP_02903192.1| pyrazinamidase/nicotinamidase [Escherich... 248 2e-64
ref|YP_050436.1| nicotinamidase/pyrazinamidase [Erwinia car... 248 2e-64
ref|ZP_02151488.1| pyrazinamidase/nicotinamidase [Phaeobact... 248 2e-64
ref|ZP_02833934.1| nicotinamidase/pyrazinamidase [Salmonell... 248 2e-64
ref|NP_767317.1| bifunctional pyrazinamidase/nicotinamidase... 248 2e-64
ref|YP_001334865.1| nicotinamidase and pyrazinamidase [Kleb... 248 2e-64
ref|ZP_00825895.1| COG1335: Amidases related to nicotinamid... 248 2e-64
ref|ZP_01062411.1| bifunctional pyrazinamidase/nicotinamida... 247 3e-64
ref|YP_001400957.1| pyrazinamidase/nicotinamidase [Yersinia... 247 3e-64
ref|ZP_03830114.1| nicotinamidase/pyrazinamidase [Pectobact... 247 3e-64
ref|NP_900934.1| bifunctional pyrazinamidase/nicotinamidase... 247 4e-64
ref|YP_275215.1| pyrazinamidase/nicotinamidase [Pseudomonas... 247 5e-64
ref|YP_125690.1| nicotinamidase/ pyrazinamidase [Legionella... 247 6e-64
ref|YP_070603.1| nicotinamidase/pyrazinamidase [Yersinia ps... 247 6e-64
ref|YP_122685.1| nicotinamidase/ pyrazinamidase [Legionella... 247 6e-64
ref|YP_001927012.1| Nicotinamidase [Methylobacterium populi... 247 6e-64
ref|NP_405705.1| nicotinamidase/pyrazinamidase [Yersinia pe... 247 6e-64
ref|ZP_02379340.1| Nicotinamidase [Burkholderia ubonensis Bu] 246 7e-64
ref|ZP_01945589.1| isochorismatase family protein [Coxiella... 246 7e-64
ref|ZP_02854449.1| Nicotinamidase [Rhizobium leguminosarum ... 246 9e-64
ref|YP_428084.1| Nicotinamidase [Rhodospirillum rubrum ATCC... 246 1e-63
ref|YP_001166243.1| Nicotinamidase [Rhodobacter sphaeroides... 246 1e-63
ref|ZP_02189181.1| isochorismatase hydrolase [alpha proteob... 245 1e-63
ref|NP_793078.1| pyrazinamidase/nicotinamidase [Pseudomonas... 245 1e-63
ref|ZP_00416936.1| Nicotinamidase [Azotobacter vinelandii A... 245 1e-63
ref|ZP_03836463.1| nicotinamidase/pyrazinamidase [Citrobact... 245 1e-63
ref|ZP_01740438.1| Nicotinamidase [Rhodobacterales bacteriu... 245 2e-63
ref|NP_771189.1| pyrazinamidase/nicotinamidase [Bradyrhizob... 245 2e-63
gb|EEH92677.1| conserved hypothetical protein [Citrobacter ... 245 2e-63
ref|YP_001808522.1| Nicotinamidase [Burkholderia ambifaria ... 245 2e-63
ref|ZP_00979781.1| COG1335: Amidases related to nicotinamid... 245 2e-63
ref|ZP_00628264.1| Nicotinamidase [Paracoccus denitrificans... 245 2e-63
ref|ZP_02911546.1| Nicotinamidase [Burkholderia ambifaria M... 244 3e-63
ref|YP_001821378.1| Nicotinamidase [Opitutus terrae PB90-1]... 244 3e-63
ref|YP_001770067.1| Nicotinamidase [Methylobacterium sp. 4-... 244 3e-63
ref|YP_001899019.1| Nicotinamidase [Ralstonia pickettii 12J... 244 3e-63
ref|YP_369444.1| Nicotinamidase [Burkholderia sp. 383] >gi|... 244 4e-63
ref|ZP_01749818.1| Nicotinamidase [Roseobacter sp. CCS2] >g... 244 4e-63
ref|YP_001204196.1| nicotinamidase/pyrazinamidase [Bradyrhi... 244 4e-63
ref|ZP_03825122.1| nicotinamidase/pyrazinamidase [Pectobact... 244 4e-63
ref|YP_001424387.1| isochorismatase family protein [Coxiell... 243 4e-63
ref|YP_216302.1| nicotinamidase/pyrazinamidase [Salmonella ... 243 5e-63
ref|ZP_02218673.1| isochorismatase family protein [Coxiella... 243 5e-63
ref|YP_002756145.1| isochorismatase family protein [Acidoba... 243 5e-63
ref|ZP_01717575.1| pyrazinamidase/nicotinamidase [Algoripha... 243 6e-63
ref|YP_033910.1| Pyrazinamidase /nicotinamidase pncA [Barto... 243 7e-63
ref|YP_001765211.1| Nicotinamidase [Burkholderia cenocepaci... 243 8e-63
ref|YP_342331.1| Nicotinamidase [Nitrosococcus oceani ATCC ... 243 8e-63
ref|ZP_02892197.1| Nicotinamidase [Burkholderia ambifaria I... 243 8e-63
ref|ZP_01908379.1| nicotinamidase/pyrazinamidase [Plesiocys... 243 9e-63
ref|YP_680973.1| pyrazinamidase/nicotinamidase [Roseobacter... 242 9e-63
ref|XP_001417004.1| predicted protein [Ostreococcus lucimar... 242 1e-62
ref|YP_001754321.1| Nicotinamidase [Methylobacterium radiot... 242 1e-62
ref|ZP_02010336.1| Nicotinamidase [Ralstonia pickettii 12D]... 242 1e-62
ref|YP_001236392.1| Putative pyrazinamidase/nicotinamidase ... 242 1e-62
ref|YP_835549.1| Nicotinamidase [Burkholderia cenocepacia H... 242 1e-62
ref|ZP_02142971.1| pyrazinamidase/nicotinamidase [Roseobact... 242 1e-62
ref|XP_001912686.1| unnamed protein product [Podospora anse... 242 1e-62
ref|YP_773783.1| Nicotinamidase [Burkholderia ambifaria AMM... 242 1e-62
ref|ZP_02055269.1| Nicotinamidase [Methylobacterium chlorom... 242 1e-62
ref|XP_364131.1| hypothetical protein MGG_08976 [Magnaporth... 242 1e-62
ref|NP_519881.1| PROBABLE BIFUNCTIONAL PROTEIN: PYRAZINAMID... 242 1e-62
ref|ZP_03965982.1| nicotinamidase [Sphingobacterium spiriti... 242 2e-62
ref|NP_929791.1| nicotinamidase/pyrazinamidase [Photorhabdu... 242 2e-62
ref|YP_001086413.1| hypothetical protein A1S_3422 [Acinetob... 241 2e-62
ref|ZP_03840187.1| pyrazinamidase/nicotinamidase [Proteus m... 241 2e-62
ref|YP_236195.1| Nicotinamidase [Pseudomonas syringae pv. s... 241 3e-62
gb|ABC25334.1| pyrazinamidase/nicotinamidase [uncultured ma... 240 3e-62
ref|YP_001907502.1| Pyrazinamidase/nicotinamidase [Erwinia ... 240 4e-62
ref|ZP_00945621.1| Pyrazinamidase / Nicotinamidase [Ralston... 240 4e-62
gb|ACO60641.1| nicotinamidase/pyrazinamidase domain-contain... 240 4e-62
ref|YP_626011.1| Nicotinamidase [Burkholderia cenocepacia A... 240 6e-62
ref|XP_888958.1| hypothetical protein CaJ7.0402 [Candida al... 240 6e-62
ref|ZP_01440157.1| bifunctional pyrazinamidase/nicotinamida... 240 7e-62
ref|ZP_02997772.1| hypothetical protein PROSTU_02771 [Provi... 239 1e-61
ref|YP_001119675.1| Nicotinamidase [Burkholderia vietnamien... 239 1e-61
ref|XP_001593095.1| hypothetical protein SS1G_06017 [Sclero... 238 2e-61
ref|YP_442664.1| pyrazinamidase/nicotinamidase [Burkholderi... 238 2e-61
ref|YP_108047.1| putative pyrazinamidase/nicotinamidase [Bu... 238 2e-61
ref|ZP_02402385.1| pyrazinamidase/nicotinamidase [Burkholde... 238 3e-61
gb|EDN16169.1| pyrazinamidase/nicotinamidase [Vibrio choler... 237 3e-61
ref|ZP_01764334.1| pyrazinamidase/nicotinamidase [Burkholde... 237 3e-61
ref|NP_986013.1| AFR466Cp [Ashbya gossypii ATCC 10895] >gi|... 237 4e-61
ref|ZP_02120069.1| Nicotinamidase [Methylobacterium nodulan... 237 5e-61
ref|YP_726027.1| Bifunctional Pyrazinamidase/Nicotinamidase... 237 6e-61
ref|YP_103089.1| pyrazinamidase/nicotinamidase [Burkholderi... 236 9e-61
ref|XP_001218134.1| conserved hypothetical protein [Aspergi... 236 9e-61
ref|ZP_00986621.1| COG1335: Amidases related to nicotinamid... 236 9e-61
ref|YP_742097.1| Nicotinamidase [Alkalilimnicola ehrlichei ... 235 1e-60
ref|ZP_01955355.1| pyrazinamidase/nicotinamidase [Vibrio ch... 235 1e-60
ref|ZP_01675333.1| pyrazinamidase/nicotinamidase [Vibrio ch... 235 1e-60
ref|XP_001559960.1| hypothetical protein BC1G_01519 [Botryo... 235 2e-60
ref|NP_233099.1| pyrazinamidase/nicotinamidase [Vibrio chol... 235 2e-60
ref|ZP_03850627.1| Nicotinamidase [Chryseobacterium gleum A... 235 2e-60
ref|NP_355032.2| pyrazinamidase/nicotinamidase [Agrobacteri... 234 3e-60
ref|YP_863199.1| bifunctional pyrazinamidase/nicotinamidase... 234 3e-60
ref|ZP_01225532.1| amidase [Aurantimonas sp. SI85-9A1] >gi|... 233 5e-60
ref|ZP_01644702.1| Nicotinamidase [Stenotrophomonas maltoph... 233 7e-60
ref|YP_001003310.1| Nicotinamidase [Halorhodospira halophil... 233 8e-60
ref|YP_184063.1| probable nicotinamidase [Thermococcus koda... 233 8e-60
ref|XP_749509.1| isochorismatase family hydrolase [Aspergi... 232 1e-59
gb|EEH61072.1| predicted protein [Micromonas pusilla CCMP1545] 232 1e-59
gb|EDP54034.1| isochorismatase family hydrolase, putative ... 232 1e-59
ref|YP_574915.1| Nicotinamidase [Chromohalobacter salexigen... 231 2e-59
ref|XP_458267.1| hypothetical protein DEHA0C14564g [Debaryo... 231 3e-59
ref|NP_126660.1| pyrazinamidase/nicotinamidase [Pyrococcus ... 230 4e-59
ref|YP_001527198.1| bifunctional pyrazinamidase [Azorhizobi... 230 4e-59
ref|ZP_01252529.1| bifunctional pyrazinamidase/nicotinamida... 230 8e-59
ref|ZP_02179817.1| pyrazinamidase/nicotinamidase [Hydrogeni... 230 8e-59
ref|YP_001830086.1| Nicotinamidase [Xylella fastidiosa M23]... 229 1e-58
ref|NP_779510.1| pyrazinamidase/nicotinamidase [Xylella fas... 229 1e-58
ref|YP_001579554.1| Nicotinamidase [Burkholderia multivoran... 228 2e-58
ref|YP_001415264.1| Nicotinamidase [Xanthobacter autotrophi... 228 3e-58
ref|ZP_00650768.1| Isochorismatase hydrolase [Xylella fasti... 228 3e-58
ref|NP_142913.1| pyrazinamidase/nicotinamidase [Pyrococcus ... 227 4e-58
ref|NP_578834.1| pyrazinamidase/nicotinamidase pxnc [Pyroco... 227 5e-58
ref|XP_389372.1| hypothetical protein FG09196.1 [Gibberella... 227 5e-58
ref|YP_001233233.1| Nicotinamidase [Acidiphilium cryptum JF... 226 8e-58
ref|ZP_00682047.1| Isochorismatase hydrolase [Xylella fasti... 226 1e-57
ref|ZP_02324315.1| Nicotinamidase [Anaeromyxobacter dehalog... 226 1e-57
ref|XP_001245038.1| hypothetical protein CIMG_04479 [Coccid... 225 1e-57
ref|YP_001379630.1| Nicotinamidase [Anaeromyxobacter sp. Fw... 224 3e-57
ref|XP_001818423.1| hypothetical protein [Aspergillus oryza... 224 3e-57
ref|XP_001874048.1| predicted protein [Laccaria bicolor S23... 223 5e-57
ref|XP_964547.1| hypothetical protein NCU00713 [Neurospora ... 223 8e-57
ref|ZP_02751610.1| nicotinamidase/pyrazinamidase [Escherich... 223 9e-57
ref|XP_001581110.1| isochorismatase family protein [Trichom... 223 9e-57
ref|XP_001829253.1| hypothetical protein CC1G_06590 [Coprin... 222 2e-56
ref|XP_500320.1| hypothetical protein [Yarrowia lipolytica]... 221 3e-56
ref|ZP_02175503.1| Nicotinamidase [Anaeromyxobacter sp. K] ... 220 4e-56
ref|ZP_02165609.1| pyrazinamidase/nicotinamidase [Hoeflea p... 220 4e-56
ref|NP_213680.1| pyrazinamidase/nicotinamidase [Aquifex aeo... 220 5e-56
ref|XP_001391911.1| hypothetical protein An07g08360 [Asperg... 220 8e-56
ref|XP_001523752.1| hypothetical protein LELG_05168 [Lodder... 218 2e-55
ref|XP_001800076.1| hypothetical protein SNOG_09789 [Phaeos... 218 2e-55
ref|XP_001482603.1| hypothetical protein PGUG_05623 [Pichia... 218 2e-55
ref|XP_001184470.1| PREDICTED: similar to pyrazinamidase/ni... 218 2e-55
ref|XP_001201249.1| PREDICTED: similar to pyrazinamidase/ni... 217 5e-55
ref|XP_001385959.2| NAD(+) salvage pathway gene [Pichia sti... 216 6e-55
ref|YP_464529.1| Nicotinamidase [Anaeromyxobacter dehalogen... 216 9e-55
ref|YP_865128.1| Nicotinamidase [Magnetococcus sp. MC-1] >g... 216 1e-54
ref|ZP_02178583.1| pyrazinamidase/nicotinamidase [Hydrogeni... 215 1e-54
ref|XP_001662895.1| pyrazinamidase/nicotinamidase [Aedes ae... 215 1e-54
ref|YP_115158.1| pyrazinamidase/nicotinamidase, putative [M... 215 2e-54
ref|YP_001737248.1| isochorismatase hydrolase [Candidatus K... 213 5e-54
ref|XP_001272808.1| isochorismatase family hydrolase, puta... 213 5e-54
ref|XP_001032952.1| isochorismatase family protein [Tetrahy... 213 8e-54
ref|XP_001455380.1| hypothetical protein GSPATT00002951001 ... 211 3e-53
ref|XP_629052.1| nicotinamidase [Dictyostelium discoideum A... 211 3e-53
ref|XP_001859965.1| pyrazinamidase/nicotinamidase [Culex pi... 211 4e-53
ref|XP_001425684.1| hypothetical protein GSPATT00004658001 ... 211 4e-53
gb|ACO14708.1| Pyrazinamidase/nicotinamidase [Caligus cleme... 210 8e-53
ref|XP_321695.4| AGAP001435-PA [Anopheles gambiae str. PEST... 210 8e-53
ref|NP_953339.1| pyrazinamidase/nicotinamidase, putative [G... 209 1e-52
ref|XP_973348.1| PREDICTED: similar to CG31216-PA [Triboliu... 209 1e-52
ref|YP_190619.1| Pyrazinamidase/nicotinamidase [Gluconobact... 208 2e-52
ref|XP_001708441.1| Pyrazinamidase/nicotinamidase [Giardia ... 208 2e-52
ref|XP_001636465.1| predicted protein [Nematostella vectens... 207 3e-52
ref|ZP_02984563.1| isochorismatase hydrolase [Gluconacetoba... 207 3e-52
ref|XP_001540638.1| conserved hypothetical protein [Ajellom... 207 4e-52
ref|ZP_02463173.1| pyrazinamidase/nicotinamidase [Burkholde... 207 4e-52
ref|XP_001747826.1| predicted protein [Monosiga brevicollis... 207 5e-52
ref|XP_567125.1| nicotinamidase [Cryptococcus neoformans va... 207 5e-52
ref|XP_396928.2| PREDICTED: similar to CG31216-PA [Apis mel... 206 8e-52
ref|XP_812349.1| alpha/beta-hydrolase, putative [Trypanosom... 206 1e-51
ref|XP_001671258.1| Hypothetical protein CBG01661 [Caenorha... 205 1e-51
ref|YP_001230506.1| isochorismatase hydrolase [Geobacter ur... 205 2e-51
ref|ZP_02530352.1| pyrazinamidase/nicotinamidase (pncA) [Bo... 204 4e-51
ref|XP_967306.1| PREDICTED: similar to CG31216-PA [Triboliu... 203 5e-51
ref|NP_499876.1| Y38C1AA.3 [Caenorhabditis elegans] >gi|145... 203 6e-51
ref|ZP_01388134.1| Isochorismatase hydrolase [Geobacter sp.... 203 7e-51
ref|YP_385324.1| Isochorismatase hydrolase [Geobacter metal... 203 1e-50
ref|XP_001601573.1| PREDICTED: similar to pyrazinamidase/ni... 202 1e-50
ref|XP_805731.1| alpha/beta-hydrolase, putative [Trypanosom... 202 1e-50
ref|YP_411601.1| Isochorismatase hydrolase [Nitrosospira mu... 202 1e-50
gb|ABV02586.1| Pyrazinamidase and nicotinamidase protein 1,... 202 1e-50
ref|NP_627144.1| nicotinamidase [Streptomyces coelicolor A3... 202 1e-50
ref|YP_001930794.1| isochorismatase hydrolase [Sulfurihydro... 202 2e-50
ref|XP_624903.1| PREDICTED: similar to CG31216-PA isoform 2... 201 2e-50
ref|YP_522109.1| isochorismatase hydrolase [Rhodoferax ferr... 201 3e-50
ref|NP_732446.1| CG31216 CG31216-PA [Drosophila melanogaste... 201 3e-50
ref|XP_001601712.1| PREDICTED: similar to LD05707p [Nasonia... 200 5e-50
ref|NP_216559.1| PYRAZINAMIDASE/NICOTINAMIDAS PNCA (PZase) ... 199 1e-49
gb|EEJ96414.1| nicotinamidase-like amidase [Thermomonospora... 198 2e-49
gb|AAV33185.1| pyrazinamidase [Mycobacterium tuberculosis] 198 2e-49
gb|AAV33195.1| pyrazinamidase [Mycobacterium tuberculosis] 198 3e-49
ref|ZP_02552703.1| pyrazinamidase/nicotinamidase pncA [Myco... 197 4e-49
gb|AAV33207.1| truncated pyrazinamidase [Mycobacterium tube... 197 5e-49
gb|AAV33179.1| pyrazinamidase [Mycobacterium tuberculosis] 196 7e-49
gb|AAV33181.1| pyrazinamidase [Mycobacterium tuberculosis] 196 7e-49
gb|AAV33208.1| truncated pyrazinamidase [Mycobacterium tube... 196 8e-49
gb|AAV33194.1| pyrazinamidase [Mycobacterium tuberculosis] 196 8e-49
ref|XP_803697.1| alpha/beta-hydrolase-like protein [Trypano... 196 8e-49
gb|AAV33188.1| pyrazinamidase [Mycobacterium tuberculosis] 196 9e-49
gb|AAV33210.1| truncated pyrazinamidase [Mycobacterium tube... 196 1e-48
gb|AAV33196.1| pyrazinamidase [Mycobacterium tuberculosis] 196 1e-48
gb|AAV33204.1| pyrazinamidase [Mycobacterium tuberculosis] 196 1e-48
Sequences not found previously or not previously below threshold:
>ref|NP_011478.1| Nicotinamidase that converts nicotinamide to nicotinic acid as part
of the NAD(+) salvage pathway, required for life span
extension by calorie restriction; PNC1 expression
responds to all known stimuli that extend replicative
life span; Pnc1p [Saccharomyces cerevisiae]
sp|P53184|PNC1_YEAST Nicotinamidase (Nicotine deamidase) (NAMase)
pdb|2H0R|A Chain A, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|B Chain B, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|C Chain C, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|D Chain D, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|E Chain E, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|F Chain F, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|G Chain G, Structure Of The Yeast Nicotinamidase Pnc1p
emb|CAA96739.1| unnamed protein product [Saccharomyces cerevisiae]
gb|AAS56807.1| YGL037C [Saccharomyces cerevisiae]
gb|EDN61566.1| nicotinamidase [Saccharomyces cerevisiae YJM789]
Length = 216
Score = 319 bits (819), Expect = 8e-86, Method: Composition-based stats.
Identities = 216/216 (100%), Positives = 216/216 (100%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF
Sbjct: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV
Sbjct: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY
Sbjct: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK
Sbjct: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
>ref|XP_444840.1| hypothetical protein CAGL0A01716g [Candida glabrata CBS138]
emb|CAG57733.1| unnamed protein product [Candida glabrata CBS 138]
Length = 211
Score = 269 bits (688), Expect = 1e-70, Method: Composition-based stats.
Identities = 129/213 (60%), Positives = 172/213 (80%), Gaps = 3/213 (1%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
MKTL+V+D+QNDFI+P S+ VP+GEE+++PI +LM+D WHR+VV+RDWHP HISF
Sbjct: 1 MKTLLVIDVQNDFITPDHSMYVPQGEEVVSPIVELMKDPQ--WHRVVVSRDWHPQNHISF 58
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
AKNH E Y+ TY SPRPGDDSTQ LWPVHCV+NT G+QL I++ V +KHIKIV
Sbjct: 59 AKNH-GVEDYTETTYKSPRPGDDSTQPATLWPVHCVQNTRGAQLAPDILELVNSKHIKIV 117
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
DKG+L++ EYYSAF+D W +HKT++++YL+KHHT EVY+VG+AL++CVK TAISAA+LGY
Sbjct: 118 DKGYLSNCEYYSAFNDTWEWHKTELDEYLKKHHTTEVYVVGLALDFCVKNTAISAAKLGY 177
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
TT+L DYT+PI D + +++++LK HN+ V
Sbjct: 178 DTTILKDYTKPIYTDEDHQQQLEKDLKEHNVKV 210
>ref|YP_002824764.1| pyrazinamidase/nicotinamidase [Rhizobium sp. NGR234]
gb|ACP24011.1| pyrazinamidase/nicotinamidase [Rhizobium sp. NGR234]
Length = 199
Score = 268 bits (687), Expect = 2e-70, Method: Composition-based stats.
Identities = 65/212 (30%), Positives = 110/212 (51%), Gaps = 17/212 (8%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
LIV+DMQNDF P G+L V G+E++ ++ L++ A +++T+DWHP+ H SFA
Sbjct: 5 ALIVIDMQNDFC-PGGALAVAGGDEIVPVVNSLIEKAK----HVILTQDWHPAGHSSFAS 59
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
+H K P+ T T E LWP HCV+ + G+ + T ++ K
Sbjct: 60 SHPGKAPFQTVTM--------PYGEQTLWPDHCVQGSPGADFHPALR---WTTAELVIRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF T + YSAF + + T + YL + +V + G+A ++CV +A+ A G+ T
Sbjct: 109 GFRTGIDSYSAFFENDHRTPTGLAGYLRERGISKVSLCGLATDFCVAFSALDAVAEGFST 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
+V+LD R I + + + ++ + ++
Sbjct: 169 SVVLDACRGIDLNGSLAAMTRR-MRDAGVELI 199
>ref|NP_539463.1| PYRAZINAMIDASE / NICOTINAMIDASE [Brucella melitensis 16M]
gb|AAL51727.1| PYRAZINAMIDASE / NICOTINAMIDASE [Brucella melitensis 16M]
Length = 251
Score = 266 bits (681), Expect = 6e-70, Method: Composition-based stats.
Identities = 67/214 (31%), Positives = 118/214 (55%), Gaps = 17/214 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+V+D+QNDF P G+L V +G+E+I ++ L+ +++ +VVT+DWHP+ H SFA
Sbjct: 47 ALVVIDVQNDFC-PGGALAVERGDEIIPIVNRLIGESEN----VVVTQDWHPANHSSFAS 101
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
NH P+ T S +LWP HCV+N+ G++ + + +V K
Sbjct: 102 NHSGSRPFDTVNM--------SYGPQVLWPDHCVQNSEGAEFHPDLQWW---RAQLVVRK 150
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF + YSAF + + T + YL + + + +VG+A ++CV ++A+ A + G++
Sbjct: 151 GFRIGIDSYSAFFENDHCTPTGLGGYLRERNIGSLTMVGLATDFCVASSALDAVQQGFQV 210
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I + +N + E++K + ++D+
Sbjct: 211 RVRLDACRGIDLN-GSMNIMLEKMKQAGVELIDE 243
>ref|YP_222148.1| PncA, pyrazinamidase/nicotinamidase [Brucella abortus biovar 1 str.
9-941]
ref|YP_414852.1| Isochorismatase hydrolase family [Brucella melitensis biovar
Abortus 2308]
ref|YP_001935354.1| Isochorismatase hydrolase family [Brucella abortus S19]
gb|AAX74787.1| PncA, pyrazinamidase/nicotinamidase [Brucella abortus biovar 1 str.
9-941]
emb|CAJ11440.1| Isochorismatase hydrolase family [Brucella melitensis biovar
Abortus 2308]
gb|ACD72880.1| Isochorismatase hydrolase family [Brucella abortus S19]
Length = 209
Score = 266 bits (681), Expect = 7e-70, Method: Composition-based stats.
Identities = 67/214 (31%), Positives = 119/214 (55%), Gaps = 17/214 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+V+D+QNDF P G+L V +G+E+I ++ L+ ++++ +VVT+DWHP+ H SFA
Sbjct: 5 ALVVIDVQNDFC-PGGALAVERGDEIIPIVNRLIGESEK----VVVTQDWHPANHSSFAS 59
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
NH P+ T S +LWP HCV+N+ G++ + + +V K
Sbjct: 60 NHSGSRPFDTVNM--------SYGPQVLWPDHCVQNSEGAEFHPDLQWW---RAQLVVRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF + YSAF + + T + YL + + + +VG+A ++CV ++A+ A + G++
Sbjct: 109 GFRIGIDSYSAFFENDHCTPTGLGGYLRERNIGSLTMVGLATDFCVASSALDAVQQGFQV 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I + +N + E++K + ++D+
Sbjct: 169 RVRLDACRGIDLN-GSMNIMLEKMKQAGVELIDE 201
>ref|YP_001593297.1| Nicotinamidase [Brucella canis ATCC 23365]
gb|ABX62526.1| Nicotinamidase [Brucella canis ATCC 23365]
Length = 209
Score = 264 bits (676), Expect = 2e-69, Method: Composition-based stats.
Identities = 66/214 (30%), Positives = 116/214 (54%), Gaps = 17/214 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+V+D+QNDF P G+L V +G+E+I ++ L+ +++ +VVT+DWHP+ H SFA
Sbjct: 5 ALVVIDVQNDFC-PGGALAVERGDEIIPIVNRLIGESEN----VVVTQDWHPANHSSFAS 59
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
NH P+ T S +LWP HCV+N+ G++ + + +V K
Sbjct: 60 NHPGSRPFDTVNM--------SYGPQVLWPDHCVQNSEGAEFHPDLQWW---RAQLVVRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G + YSAF + + T + YL + + + +VG+A ++CV +A+ A + G++
Sbjct: 109 GVRIGIDSYSAFFENDHCTPTGLGGYLRERNIGSLTMVGLATDFCVACSALDAVQQGFQV 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I + +N + E++K + ++D+
Sbjct: 169 RVRLDACRGIDLN-GSMNIMLEKMKQAGVELIDE 201
>ref|YP_001628120.1| Nicotinamidase [Brucella suis ATCC 23445]
gb|ABY38550.1| Nicotinamidase [Brucella suis ATCC 23445]
Length = 209
Score = 264 bits (676), Expect = 3e-69, Method: Composition-based stats.
Identities = 66/214 (30%), Positives = 117/214 (54%), Gaps = 17/214 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+V+D+QNDF P G+L V +G+E+I ++ L+ +++ +VVT+DWHP+ H SFA
Sbjct: 5 ALVVIDVQNDFC-PGGALAVERGDEIIPIVNRLIGESEN----VVVTQDWHPANHSSFAS 59
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
NH P+ T S +LWP HCV+N+ G++ + + +V K
Sbjct: 60 NHPGSRPFDTVNM--------SYGPQVLWPDHCVQNSEGAEFHPDLQWW---RAQLVVRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G + YSAF + + T + YL + + + +VG+A ++CV ++A+ A + G++
Sbjct: 109 GVRIGCDSYSAFFENDHCTPTGLGGYLRERNIGSLTMVGLATDFCVASSALDAVQQGFQV 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I + +N + E++K + ++D+
Sbjct: 169 RVRLDACRGIDLN-GSMNIMLEKMKQAGVELIDE 201
>ref|ZP_01853806.1| pyrazinamidase/nicotinamidase [Planctomyces maris DSM 8797]
gb|EDL60134.1| pyrazinamidase/nicotinamidase [Planctomyces maris DSM 8797]
Length = 199
Score = 264 bits (676), Expect = 3e-69, Method: Composition-based stats.
Identities = 71/215 (33%), Positives = 122/215 (56%), Gaps = 16/215 (7%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M+ LI+VD+Q DF+ P GSL VP+G++++ ++LM D+ +V T+DWHP+ H+SF
Sbjct: 1 MRALILVDLQYDFM-PGGSLAVPEGDQVVPIANELMS----DFDLVVATQDWHPADHLSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
A H D+E D + E ILWP HCV+ T G++L + + + I
Sbjct: 56 ASQHPDREIGEQI--------DLAGLEQILWPDHCVQGTRGAELHADLKQNQLDR---IF 104
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KG + YS F+D + T M +YL++ V ++G+A +YCVK TA+ A +LG+
Sbjct: 105 PKGTDRLIDSYSGFYDNGHQKSTGMGEYLKEQGVQSVTVLGLAADYCVKWTALDAVKLGF 164
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
+T++ L R + P +++ +E++ + +++
Sbjct: 165 QTSLSLRGCRGVDLSPGDVHRAYQEMQNAGVEIIE 199
>ref|YP_611664.1| Nicotinamidase [Silicibacter sp. TM1040]
gb|ABF62402.1| Nicotinamidase [Silicibacter sp. TM1040]
Length = 201
Score = 264 bits (675), Expect = 4e-69, Method: Composition-based stats.
Identities = 61/212 (28%), Positives = 109/212 (51%), Gaps = 18/212 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L+V+D+QNDF P G+L V +G+E++ PI+ +M+ + +++T+DWHP H SFA
Sbjct: 7 QALLVIDVQNDFC-PGGALAVTEGDEVVAPINAMME----RFDTVILTQDWHPKGHSSFA 61
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H P+ T + + ++WP HCV+ + G++ ++ T I+
Sbjct: 62 SSHPGHAPFDTMEMY--------YGQQVMWPDHCVQGSQGAEFHPRLR----TDGDMIIR 109
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + + YSAF + T + YL ++ +VG+A ++CV +A+ A LG+
Sbjct: 110 KGFRPEVDSYSAFFENDQTTPTGLEGYLRTRGISDLTLVGLATDFCVAFSALDARRLGFS 169
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V L R I D + E ++ + +
Sbjct: 170 VEVELAACRAIDLD-GSLATQLENMRQKGVKI 200
>ref|NP_384685.1| PROBABLE PYRAZINAMIDASE/NICOTINAMIDASE (INCLUDES: PYRAZINAMIDASE,
NICOTINAMIDASE) PROTEIN [Sinorhizobium meliloti 1021]
gb|AAF76877.1|AF247710_2 putative pyrazinamidase/nicotinamidase PncA [Sinorhizobium
meliloti]
emb|CAC45151.1| Probable pyrazinamidase/nicotinamidase (includes: pyrazinamidase,
nicotinamidase) [Sinorhizobium meliloti 1021]
Length = 211
Score = 263 bits (674), Expect = 4e-69, Method: Composition-based stats.
Identities = 62/213 (29%), Positives = 105/213 (49%), Gaps = 17/213 (7%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ LIV+DMQNDF P G+L V G+E++ ++ L+ + +V+T+DWHP+ H SFA
Sbjct: 16 EALIVIDMQNDFC-PGGALAVEGGDEIVPAVNRLIDASP----HVVLTQDWHPAGHSSFA 70
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H K P+ T E LWP HCV+ + G+ + T ++
Sbjct: 71 STHPGKAPFQTVAM--------PYGEQTLWPEHCVQGSAGADFHPSLR---WTSAELVIR 119
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + + YSAF + + T + YL + V + G+A ++CV +A+ A G+
Sbjct: 120 KGFRREIDSYSAFFENDHRTPTGLAGYLRERGIRSVTLCGLATDFCVAFSALDAVAKGFS 179
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
T+V+L R I + + ++ + ++
Sbjct: 180 TSVVLGACRGIDLNGSLAAMTLR-MRDAGVRLI 211
>ref|NP_698460.1| pyrazinamidase/nicotinamidase [Brucella suis 1330]
gb|AAN30375.1| pyrazinamidase/nicotinamidase [Brucella suis 1330]
Length = 209
Score = 263 bits (674), Expect = 4e-69, Method: Composition-based stats.
Identities = 65/214 (30%), Positives = 117/214 (54%), Gaps = 17/214 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+V+D+QNDF P G+L + +G+E+I ++ L+ +++ +VVT+DWHP+ H SFA
Sbjct: 5 ALVVIDVQNDFC-PGGALAIERGDEIIPIVNRLIGESEN----VVVTQDWHPANHSSFAS 59
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
NH P+ T S +LWP HCV+N+ G++ + + +V K
Sbjct: 60 NHPGSRPFDTVNM--------SYGPQVLWPDHCVQNSEGAEFHPDLQWW---RAQLVVRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G + YSAF + + T + YL + + + +VG+A ++CV ++A+ A + G++
Sbjct: 109 GVHIGIDSYSAFFENDHCTPTGLGGYLRERNIGSLTMVGLATDFCVASSALDAVQQGFQV 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I + +N + E++K + ++D+
Sbjct: 169 RVRLDACRGIDLN-GSMNIMLEKMKQAGVELIDE 201
>gb|AAG56755.1|AE005399_9 orf, hypothetical protein [Escherichia coli O157:H7 EDL933]
dbj|BAB35898.1| hypothetical protein [Escherichia coli O157:H7 str. Sakai]
Length = 219
Score = 263 bits (672), Expect = 7e-69, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|YP_445581.1| pyrazinamidase/nicotinamidase [Salinibacter ruber DSM 13855]
gb|ABC45428.1| pyrazinamidase/nicotinamidase [Salinibacter ruber DSM 13855]
Length = 208
Score = 263 bits (672), Expect = 7e-69, Method: Composition-based stats.
Identities = 64/214 (29%), Positives = 108/214 (50%), Gaps = 17/214 (7%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M L++VD+QNDF P G+L VP+G+ ++ ++ + + ++ T+DWHP+ H SF
Sbjct: 1 MDALLIVDLQNDFC-PGGALAVPEGDTIVPTVNAMAA----RFDHVIQTQDWHPAGHQSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
A +H D P + E +LWP HCV+ T G++ + I+
Sbjct: 56 ASSHPDHAPMDVI--------EVDYGEQVLWPDHCVQGTEGAEFHPDLDTAP---SELIL 104
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KGF + YSAF++ T + YL + D +Y+ G+A ++CVK +A+ E G+
Sbjct: 105 RKGFRPGIDSYSAFYENDGTTPTGLTGYLRERGIDTLYLCGLATDFCVKWSAVDGREEGF 164
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
V+ D TR I D + + +E+ + V+
Sbjct: 165 DVYVIEDATRGIDQD-GSLAQAWDEMNEAGVQVI 197
>ref|ZP_00714471.1| COG1335: Amidases related to nicotinamidase [Escherichia coli B7A]
gb|ABB65946.1| conserved hypothetical protein [Shigella boydii Sb227]
Length = 219
Score = 263 bits (672), Expect = 7e-69, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ + + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVEVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>gb|AAZ88098.1| conserved hypothetical protein [Shigella sonnei Ss046]
Length = 219
Score = 263 bits (672), Expect = 7e-69, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|ZP_02826083.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str. EC508]
Length = 213
Score = 263 bits (672), Expect = 9e-69, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_001325893.1| Nicotinamidase [Sinorhizobium medicae WSM419]
gb|ABR59058.1| Nicotinamidase [Sinorhizobium medicae WSM419]
Length = 199
Score = 262 bits (671), Expect = 9e-69, Method: Composition-based stats.
Identities = 63/212 (29%), Positives = 108/212 (50%), Gaps = 17/212 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ LIV+DMQNDF P G+L V G+E+I ++ L++ + +V+T+DWHP+ H SFA
Sbjct: 4 EALIVIDMQNDFC-PGGALAVDGGDEIIPAVNRLIETSP----HVVLTQDWHPADHSSFA 58
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H + + T T E LWP HCV+ + G+ + T ++
Sbjct: 59 SSHPGRLAFQTVTM--------PYGEQTLWPAHCVQASVGADFHPSLR---WTSAELVIR 107
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + + YSAF + + T + YL + V + G+A ++CV +A+ A G+
Sbjct: 108 KGFRREIDSYSAFFENDHRTPTGLAGYLRERGISSVTLCGLATDFCVAFSALDAVAQGFS 167
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
T+V+LD R I+ + + ++ + +
Sbjct: 168 TSVVLDACRGINLNGSLAAMTFR-MRDAGVRL 198
>gb|ABB61643.1| conserved hypothetical protein [Shigella dysenteriae Sd197]
Length = 219
Score = 262 bits (671), Expect = 1e-68, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDQEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|NP_288202.2| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 EDL933]
ref|YP_310333.2| nicotinamidase/pyrazinamidase [Shigella sonnei Ss046]
ref|NP_310502.2| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str. Sakai]
ref|ZP_02787166.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4501]
ref|YP_001724839.1| Nicotinamidase [Escherichia coli ATCC 8739]
gb|ACA77512.1| Nicotinamidase [Escherichia coli ATCC 8739]
Length = 213
Score = 262 bits (671), Expect = 1e-68, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_407774.2| nicotinamidase/pyrazinamidase [Shigella boydii Sb227]
ref|YP_001880565.1| pyrazinamidase/nicotinamidase [Shigella boydii CDC 3083-94]
gb|ACD08036.1| pyrazinamidase/nicotinamidase [Shigella boydii CDC 3083-94]
Length = 213
Score = 262 bits (670), Expect = 1e-68, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ + + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVEVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|ZP_00924703.1| COG1335: Amidases related to nicotinamidase [Escherichia coli
101-1]
Length = 219
Score = 262 bits (670), Expect = 1e-68, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLHQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|YP_403134.2| nicotinamidase/pyrazinamidase [Shigella dysenteriae Sd197]
Length = 213
Score = 262 bits (670), Expect = 1e-68, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDQEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|ZP_00720836.1| COG1335: Amidases related to nicotinamidase [Escherichia coli
E110019]
ref|ZP_00727864.1| COG1335: Amidases related to nicotinamidase [Escherichia coli E22]
Length = 219
Score = 262 bits (669), Expect = 2e-68, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQHC-VEPY--------MPGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|AP_002387.1| nicotinamidase/pyrazinamidase [Escherichia coli W3110]
ref|NP_416282.4| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr.
MG1655]
ref|YP_001458548.1| pyrazinamidase/nicotinamidase [Escherichia coli HS]
ref|YP_001730745.1| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr.
DH10B]
ref|ZP_02999827.1| pyrazinamidase/nicotinamidase [Escherichia coli 53638]
sp|P21369|PNCA_ECOLI Pyrazinamidase/nicotinamidase (PZAase) (Nicotine deamidase)
(NAMase)
gb|AAA23447.1| ORF1
dbj|BAA15559.1| nicotinamidase/pyrazinamidase [Escherichia coli W3110]
gb|AAC74838.2| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr.
MG1655]
gb|ABV06165.1| pyrazinamidase/nicotinamidase [Escherichia coli HS]
gb|ACB02967.1| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr.
DH10B]
gb|EDU62859.1| pyrazinamidase/nicotinamidase [Escherichia coli 53638]
Length = 213
Score = 262 bits (669), Expect = 2e-68, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLHQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_675744.1| isochorismatase hydrolase [Mesorhizobium sp. BNC1]
gb|ABG64579.1| isochorismatase hydrolase [Mesorhizobium sp. BNC1]
Length = 203
Score = 262 bits (669), Expect = 2e-68, Method: Composition-based stats.
Identities = 66/213 (30%), Positives = 113/213 (53%), Gaps = 17/213 (7%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ LIV+D+QNDF P G+L V +G+E++ ++ L+Q + +++T+DWHP+ H SFA
Sbjct: 8 EALIVIDVQNDFC-PGGALAVERGDEVVPVVNGLIQ----RFDHVILTQDWHPAGHSSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+ K P+ T E LWP HCV+ T G+ + TK ++
Sbjct: 63 SSQPGKAPFETVLM--------PYGEQTLWPDHCVQGTSGADFHPGL---EWTKAELVIR 111
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + + YSAF + + T ++ YL + +V + G+A ++CV +A+ A G++
Sbjct: 112 KGFRSAIDSYSAFFENDHETPTGLSGYLRERGIGKVTLAGLATDFCVAYSALDARRQGFE 171
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
TV+L+ R I + + E +KA + +V
Sbjct: 172 ATVILEACRAIDL-GGSLAVMTERMKAAGVELV 203
>ref|ZP_00710421.1| COG1335: Amidases related to nicotinamidase [Escherichia coli B171]
Length = 219
Score = 262 bits (669), Expect = 2e-68, Method: Composition-based stats.
Identities = 68/212 (32%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY PG WPVHCV+N+ G+QL + + + +
Sbjct: 69 SQHC-VEPY--------MPGQLDGLPQTFWPVHCVQNSEGAQLHPLLNQKAIAA---MFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>gb|AAN43052.1| orf, conserved hypothetical protein [Shigella flexneri 2a str. 301]
gb|AAP16947.1| hypothetical protein S1570 [Shigella flexneri 2a str. 2457T]
Length = 219
Score = 261 bits (668), Expect = 2e-68, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ + + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVEVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLGGLRQTFWPEHCVQNSEGAQLHPLLNQKEIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTALDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|ZP_00921076.1| COG1335: Amidases related to nicotinamidase [Shigella dysenteriae
1012]
Length = 219
Score = 261 bits (668), Expect = 2e-68, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHTFVEMSAAGATL 208
>ref|YP_001463067.1| pyrazinamidase/nicotinamidase [Escherichia coli E24377A]
gb|ABV17497.1| pyrazinamidase/nicotinamidase [Escherichia coli E24377A]
Length = 213
Score = 261 bits (668), Expect = 2e-68, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_688945.1| nicotinamidase/pyrazinamidase [Shigella flexneri 5 str. 8401]
ref|NP_707345.2| nicotinamidase/pyrazinamidase [Shigella flexneri 2a str. 301]
ref|NP_837140.2| nicotinamidase/pyrazinamidase [Shigella flexneri 2a str. 2457T]
gb|ABF03640.1| conserved hypothetical protein [Shigella flexneri 5 str. 8401]
Length = 213
Score = 261 bits (667), Expect = 3e-68, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ + + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVEVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLGGLRQTFWPEHCVQNSEGAQLHPLLNQKEIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTALDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_001743481.1| pyrazinamidase/nicotinamidase [Escherichia coli SMS-3-5]
gb|ACB19609.1| pyrazinamidase/nicotinamidase [Escherichia coli SMS-3-5]
Length = 213
Score = 261 bits (667), Expect = 3e-68, Method: Composition-based stats.
Identities = 68/212 (32%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLKQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ I+G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTALDDWLRDHEIDELIIMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|ZP_00999691.1| pyrazinamidase/nicotinamidase [Oceanicola batsensis HTCC2597]
gb|EAQ03265.1| pyrazinamidase/nicotinamidase [Oceanicola batsensis HTCC2597]
Length = 198
Score = 261 bits (667), Expect = 3e-68, Method: Composition-based stats.
Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 17/212 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L+V+D+QNDF P G+L V G+ ++ I+ LM + + +V+T+DWHP+ H SFA
Sbjct: 3 RALLVIDVQNDFC-PGGALAVNGGDTIVPGINQLMTE----FDAVVLTQDWHPAGHSSFA 57
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H+ KEP +LWP HC++ + G+Q + + I+
Sbjct: 58 SSHEGKEPMEMTEM--------PYGPQVLWPDHCIQGSHGAQFHPDLTT---DRADLIIR 106
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + YSAF + + T + YL +++ +VG+A ++CV +A+ AA+LG+
Sbjct: 107 KGFDPAIDSYSAFFENDHETPTGLEGYLRTRGIEDLTLVGLATDFCVNFSAVDAAKLGFG 166
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
TV D R I + + E + +
Sbjct: 167 VTVRTDLCRAIDLN-GSLQAALEGMTQAGAGI 197
>ref|ZP_01745842.1| pyrazinamidase/nicotinamidase [Sagittula stellata E-37]
gb|EBA08464.1| pyrazinamidase/nicotinamidase [Sagittula stellata E-37]
Length = 197
Score = 261 bits (667), Expect = 3e-68, Method: Composition-based stats.
Identities = 67/213 (31%), Positives = 110/213 (51%), Gaps = 17/213 (7%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M LIV+D+QNDF P G+L V +G+E++ PI+ LM + + +V+T+DWHP+ H SF
Sbjct: 1 MHALIVIDVQNDFC-PGGALAVAQGDEIVQPINALMAE----FDAVVLTQDWHPAGHSSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
A H+ K P+ D +LWP HC++ + G+ ++ + I+
Sbjct: 56 ASAHEGKAPFEMI--------DMPYGPQVLWPDHCIQASPGANFHMELET---DRADLII 104
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KGF + + YSAF + + T + YL D + +VG+A ++CV +A+ AA LG+
Sbjct: 105 RKGFRSAIDSYSAFFENDHTTPTGLEGYLRTRGIDRLTLVGLATDFCVNYSAVDAARLGF 164
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V D R I D + +E + + +
Sbjct: 165 SVAVREDLCRAIDLD-GSLKAARESMMQAGVTL 196
>ref|NP_105653.1| pyrazinamidase/nicotinamidase [Mesorhizobium loti MAFF303099]
dbj|BAB51439.1| pyrazinamidase/nicotinamidase [Mesorhizobium loti MAFF303099]
Length = 204
Score = 260 bits (666), Expect = 4e-68, Method: Composition-based stats.
Identities = 66/214 (30%), Positives = 112/214 (52%), Gaps = 17/214 (7%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L+V+D+QNDF P G+L V G+E++ ++D++ R +V+T+DWHP+ H SFA
Sbjct: 4 QALVVIDLQNDFC-PGGALAVTGGDEIVPLVNDMI----RRTDHVVLTQDWHPAGHSSFA 58
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H +P++ + LWP HC++ + GS + TK ++
Sbjct: 59 SSHPGAQPFTMIEM--------PYGQQTLWPDHCIQGSLGSDFHSGLA---WTKAELVIR 107
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF D + YSAF + + T + YL + D V +VG+A ++CV +A+ A G+K
Sbjct: 108 KGFRPDIDSYSAFFENDHTTPTGLGGYLRERGIDTVTLVGLATDFCVGFSALDAVSQGFK 167
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
TTV LD R I + + + ++ + + D
Sbjct: 168 TTVRLDACRGIDLN-GSLEAMLRRMRDAGVALED 200
>ref|ZP_02152324.1| pyrazinamidase/nicotinamidase [Oceanibulbus indolifex HEL-45]
gb|EDQ06191.1| pyrazinamidase/nicotinamidase [Oceanibulbus indolifex HEL-45]
Length = 198
Score = 260 bits (664), Expect = 6e-68, Method: Composition-based stats.
Identities = 68/211 (32%), Positives = 113/211 (53%), Gaps = 17/211 (8%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
LIV+D+QNDF P G+L VP+G+E++ I+ LM + + +V+T+DWHP+ H SFA
Sbjct: 4 ALIVIDVQNDFC-PGGALEVPQGDEILRGINALMPE----FAAVVLTQDWHPAGHSSFAS 58
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
+H PY T +LWP HC++ + G+Q + + I+ K
Sbjct: 59 SHDGNAPYEIVTM--------PYGPQVLWPDHCIQGSIGAQFHPDLQT---DRADLIIRK 107
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G+ D + YSAF + + T + YL + + +VG+AL++CV +A+ AA+LG+
Sbjct: 108 GYSPDIDSYSAFFENDHSTPTGLEGYLRTRGIERLTMVGLALDFCVNFSAVDAAKLGFNV 167
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V + R I D + K +E ++A + +
Sbjct: 168 DVREELCRAIDLD-GSLAKSREGMRAAGVTL 197
>ref|ZP_02742886.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4045]
ref|ZP_02768554.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4115]
ref|ZP_02774431.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4113]
ref|ZP_02781786.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4401]
ref|ZP_02795740.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4486]
ref|ZP_02799931.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4196]
ref|ZP_02807199.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4076]
ref|ZP_02818179.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4042]
gb|EDU33244.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4196]
gb|EDU54343.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4113]
gb|EDU69221.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4076]
Length = 213
Score = 259 bits (663), Expect = 9e-68, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSA D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSALFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|ZP_01443288.1| pyrazinamidase/nicotinamidase [Roseovarius sp. HTCC2601]
gb|EAU46422.1| pyrazinamidase/nicotinamidase [Roseovarius sp. HTCC2601]
Length = 197
Score = 259 bits (662), Expect = 1e-67, Method: Composition-based stats.
Identities = 62/213 (29%), Positives = 105/213 (49%), Gaps = 17/213 (7%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M L+V+D+QNDF P G+L V G+E++ PI+ +M + + +++T+DWHP+ H SF
Sbjct: 1 MHALVVIDVQNDFC-PGGALAVTGGDEIVAPINAMMAE----FDAVILTQDWHPAGHSSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
A H K P +LWP HCV+ + G+ ++ + I+
Sbjct: 56 ASQHPGKAPLEMTEM--------PYGPQVLWPDHCVQGSLGAAFHPRLDT---DRAELII 104
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KGF + YSAF + + T + YL D + +VG+A ++CV +A+ AA LG+
Sbjct: 105 RKGFRPGIDSYSAFFENDHETPTGLEGYLRTRGIDRLTLVGLATDFCVNFSAVDAATLGF 164
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
+ TV R I + + ++ + +
Sbjct: 165 EVTVREAACRGIDL-GGSLAVARAGMQEAGVTL 196
>ref|ZP_00725208.1| COG1335: Amidases related to nicotinamidase [Escherichia coli F11]
ref|YP_852852.1| nicotinamidase/pyrazinamidase [Escherichia coli APEC O1]
gb|AAN80631.1|AE016761_206 Pyrazinamidase/nicotinamidase [Escherichia coli CFT073]
gb|ABE07440.1| pyrazinamidase/nicotinamidase [Escherichia coli UTI89]
gb|ABJ01138.1| pyrazinamidase/nicotinamidase [Escherichia coli APEC O1]
Length = 219
Score = 259 bits (662), Expect = 1e-67, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLKQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H +E+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTALDDWLRAHVINELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|YP_584002.1| isochorismatase hydrolase [Ralstonia metallidurans CH34]
gb|ABF08733.1| isochorismatase hydrolase [Ralstonia metallidurans CH34]
Length = 221
Score = 258 bits (661), Expect = 1e-67, Method: Composition-based stats.
Identities = 68/209 (32%), Positives = 108/209 (51%), Gaps = 17/209 (8%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+V+D+QNDF+ P G+L VP+G+E++ I+ L + +V+T+DWHP+ H+SFA +
Sbjct: 9 LLVIDVQNDFM-PGGALAVPRGDEVVPIINRLAP----AFEHVVLTQDWHPAGHVSFATS 63
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
H P+ T E +LWP HCV+ T G+ L D + ++ KG
Sbjct: 64 HVGTAPFQTMML--------PYGEQVLWPDHCVQGTPGAALH---ADLRIPHARMVIRKG 112
Query: 124 FLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTT 183
+ + YSAF + KT + YL + V VG+A +YCV TA+ A G++
Sbjct: 113 HHANVDSYSAFMEADRATKTGLAGYLREQGVRRVVCVGLATDYCVAWTALDARAAGFEAV 172
Query: 184 VLLDYTRPISDDPEVINKVKEELKAHNIN 212
V+ D R I + +++ EL A +
Sbjct: 173 VVEDACRAIDLN-GSLDRAWRELAAAGVR 200
>ref|YP_001534681.1| Nicotinamidase [Dinoroseobacter shibae DFL 12]
gb|ABV95080.1| Nicotinamidase [Dinoroseobacter shibae DFL 12]
Length = 200
Score = 258 bits (661), Expect = 2e-67, Method: Composition-based stats.
Identities = 68/213 (31%), Positives = 107/213 (50%), Gaps = 17/213 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
LIV+D+QNDF P G+L V +G ++ I+ LM +A +V+T+DWHP+ H SFA
Sbjct: 4 ALIVIDVQNDFC-PGGALAVAEGNTIVPAINALMAEA----EAVVLTQDWHPAGHSSFAS 58
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
+H P S D +LWP HCV+ + G+ + T+ IV K
Sbjct: 59 SHPGAAPLSMI--------DMPYGPQVLWPDHCVQGSDGAAFHPDLDT---TRADMIVRK 107
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF + YSAF + + T ++ YL ++ +VG+A ++CV +A+ AA+LG+
Sbjct: 108 GFRPAIDSYSAFFENDHETPTGLDGYLRSRGITDLTLVGLATDFCVHYSAVDAAKLGFAV 167
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
TV D R I D + ++ + + D
Sbjct: 168 TVRTDLCRAIDLD-GSLASACTAMQEAGVRLSD 199
>ref|YP_669620.1| nicotinamidase/pyrazinamidase [Escherichia coli 536]
ref|NP_754066.2| nicotinamidase/pyrazinamidase [Escherichia coli CFT073]
ref|YP_540971.2| nicotinamidase/pyrazinamidase [Escherichia coli UTI89]
gb|ABG69719.1| pyrazinamidase/nicotinamidase [Escherichia coli 536]
Length = 213
Score = 258 bits (660), Expect = 2e-67, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLKQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H +E+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTALDDWLRAHVINELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|ZP_02813180.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str. EC869]
Length = 213
Score = 258 bits (660), Expect = 2e-67, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D ++ P+ E+ A +
Sbjct: 171 VNVITDGCHGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_001259350.1| pyrazinamidase/nicotinamidase [Brucella ovis ATCC 25840]
gb|ABQ61214.1| pyrazinamidase/nicotinamidase [Brucella ovis ATCC 25840]
Length = 209
Score = 258 bits (659), Expect = 2e-67, Method: Composition-based stats.
Identities = 66/213 (30%), Positives = 117/213 (54%), Gaps = 17/213 (7%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+V+D+QNDF P G+L V +G+E+I ++ L+ +++ +VVT+DWHP+ H SFA N
Sbjct: 6 LVVIDVQNDFC-PGGALAVERGDEIIPIVNRLIGESEN----VVVTQDWHPANHSSFASN 60
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
H P+ T S + +LWP HCV+N+ G++ + + +V KG
Sbjct: 61 HPGSRPFDTVNM--------SYRPQVLWPDHCVQNSEGAEFHPDLEWW---RAQLVVRKG 109
Query: 124 FLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTT 183
F + YSAF + + YL + + + +VG+A ++CV ++A+ A + G++
Sbjct: 110 FRIGIDSYSAFFENDLCTPAGLGGYLRERNIGSLTMVGLATDFCVASSALDAVQQGFQVR 169
Query: 184 VLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I + +N + E++K + ++D+
Sbjct: 170 VRLDACRGIDLN-GSMNIMLEKMKQAGVELIDE 201
>ref|ZP_01015636.1| pyrazinamidase/nicotinamidase [Rhodobacterales bacterium HTCC2654]
gb|EAQ10694.1| pyrazinamidase/nicotinamidase [Rhodobacterales bacterium HTCC2654]
Length = 203
Score = 257 bits (658), Expect = 3e-67, Method: Composition-based stats.
Identities = 69/213 (32%), Positives = 105/213 (49%), Gaps = 17/213 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
LIV+D+QNDF P G+L V G+E++ I+ L+ RD+ V T+DWHP+ H SFA
Sbjct: 8 ALIVIDVQNDFC-PGGALAVDGGDEIVPGINRLI----RDFPIRVFTQDWHPAGHSSFAS 62
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
+H K P D +LWP HCV+ T G+ + +M I+ K
Sbjct: 63 SHPGKAPLEMV--------DMDYGPQVLWPDHCVQGTDGAAFHEDLMT---DPADLILRK 111
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF + + YSAF + + T + YL + VG+A ++CV +A+ AA LG+
Sbjct: 112 GFRPEIDSYSAFFENDHRTSTGLEGYLRSRGATRLTFVGLATDFCVGWSAMDAARLGFAV 171
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
TV LD R I D ++ ++ ++
Sbjct: 172 TVRLDLCRAIDAD-GSLDTALAGMRDAGATLIG 203
>ref|YP_001453362.1| hypothetical protein CKO_01797 [Citrobacter koseri ATCC BAA-895]
gb|ABV12926.1| hypothetical protein CKO_01797 [Citrobacter koseri ATCC BAA-895]
Length = 213
Score = 257 bits (656), Expect = 5e-67, Method: Composition-based stats.
Identities = 61/212 (28%), Positives = 105/212 (49%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIAWCKARGDTVIASQDWHPAGHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H+ +PYS G WP HCV+N+ G+ L + + +
Sbjct: 63 SQHQ-AQPYSQ--------GQLDGLAQTFWPDHCVQNSDGAALHPLLRQNAIDA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L ++ + ++G+A +YCVK T + A +LGY
Sbjct: 111 KGENPQVDSYSAFFDNGRRQKTALDAWLRENGVQTLIVMGLATDYCVKFTVLDALQLGYT 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSTHAFMEMAAAGATL 202
>ref|ZP_01877931.1| Nicotinamidase [Roseovarius sp. TM1035]
gb|EDM33315.1| Nicotinamidase [Roseovarius sp. TM1035]
Length = 198
Score = 256 bits (655), Expect = 6e-67, Method: Composition-based stats.
Identities = 64/212 (30%), Positives = 108/212 (50%), Gaps = 17/212 (8%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
LIV+D+QNDF P G+L VP+G++++ I+ LM + +++T+DWHPS H SFA
Sbjct: 4 ALIVIDLQNDFC-PGGALAVPEGDQIVPGINALMPEFPA----VILTQDWHPSGHSSFAS 58
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
+H K Y +LWP HCV+ + G+ + + I+ K
Sbjct: 59 SHPGKSAYEMTEM--------PYGPQVLWPDHCVQGSHGAAFHQDLNTA---RADLILRK 107
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G+ + YSAF + T ++ YL+ ++ +VG+A ++CV +A+ AA LGY+
Sbjct: 108 GYNPAIDSYSAFFENDRATPTGLHGYLQTRGITDLTMVGLATDFCVNYSALDAARLGYRV 167
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
TV D R I + + + + A + ++
Sbjct: 168 TVRRDLARGIDL-GGSLAEAEAGMTAAGVTLL 198
>ref|ZP_01055578.1| pyrazinamidase/nicotinamidase [Roseobacter sp. MED193]
gb|EAQ46521.1| pyrazinamidase/nicotinamidase [Roseobacter sp. MED193]
Length = 199
Score = 256 bits (654), Expect = 9e-67, Method: Composition-based stats.
Identities = 68/212 (32%), Positives = 108/212 (50%), Gaps = 18/212 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ LIVVD+QNDF P G+L VP G+E++ PI+ +M +D+ +++T+DWHP+ H SFA
Sbjct: 3 QALIVVDVQNDFC-PGGALAVPGGDEVVVPINAMM----KDFETVILTQDWHPAGHSSFA 57
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H P T S +LWP HC++ + G+ + I+
Sbjct: 58 SSHPGMSPLETLEM--------SYGTQVLWPDHCIQGSQGAAFHPALD----LSGDLIIR 105
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + + YSAF + T + YL E+ VG+A ++CV +A+ AA LG++
Sbjct: 106 KGFRSAIDSYSAFFENDQLTPTGLEGYLRSRGISELTFVGLATDFCVAFSALDAARLGFQ 165
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V L R I + K +++A + V
Sbjct: 166 AKVELAACRGIDL-GGSLAKSLTDMQAAGVQV 196
>ref|ZP_01756653.1| pyrazinamidase/nicotinamidase [Roseobacter sp. SK209-2-6]
gb|EBA14615.1| pyrazinamidase/nicotinamidase [Roseobacter sp. SK209-2-6]
Length = 198
Score = 256 bits (654), Expect = 9e-67, Method: Composition-based stats.
Identities = 70/212 (33%), Positives = 110/212 (51%), Gaps = 18/212 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+TLIV+D+QNDF P G+L VP G+E++ PI+ +M D+ +V+T+DWHP H SFA
Sbjct: 3 ETLIVIDVQNDFC-PGGALAVPGGDEVVAPINAMMA----DFDAVVLTQDWHPHGHSSFA 57
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H+ K P+ T S +LWP HCV+ G+ + T+ I+
Sbjct: 58 ASHEGKAPFETIEL--------SYGTQVLWPEHCVQGEKGADFHGDLN----TQADLIIR 105
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + YSAF + T + YL ++ + G+A ++CV +A+ AA LG+
Sbjct: 106 KGFRPAIDSYSAFFENDQKTPTGLEGYLRDRGLQKLTLAGLATDFCVAFSALDAARLGFD 165
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
TV L R I + ++K +K + +
Sbjct: 166 VTVALSACRAIDLE-GSLDKAMTRMKEAGVRI 196
>ref|YP_001370254.1| Nicotinamidase [Ochrobactrum anthropi ATCC 49188]
gb|ABS14425.1| Nicotinamidase [Ochrobactrum anthropi ATCC 49188]
Length = 209
Score = 255 bits (652), Expect = 2e-66, Method: Composition-based stats.
Identities = 60/214 (28%), Positives = 111/214 (51%), Gaps = 17/214 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+VVD+QNDF P G+L V +G+E+I ++ L+ ++ +++T+DWHP+ H SFA
Sbjct: 5 ALVVVDIQNDFC-PGGALAVDRGDEIIPTVNRLIDES----EHVILTQDWHPANHSSFAS 59
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
H +P+ T + LWP HCV+ G+ + T+ ++ K
Sbjct: 60 THAHAQPFDTIEM--------AYGLQTLWPDHCVQGRHGADFHANLQ---WTRAQLVIRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF + YSAF + T + YL + + + + G+A ++CV +A+ A G++
Sbjct: 109 GFRIGIDSYSAFFENDRSTPTGLGGYLRERNIGSLTLAGLATDFCVAYSALDAIAEGFQV 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I+ + ++ + +++K + ++D+
Sbjct: 169 RVRLDACRGINLN-GSMDIMLQKMKQAGVELIDE 201
>ref|ZP_00954335.1| pyrazinamidase/nicotinamidase [Sulfitobacter sp. EE-36]
gb|EAP85568.1| pyrazinamidase/nicotinamidase [Sulfitobacter sp. EE-36]
Length = 226
Score = 254 bits (650), Expect = 2e-66, Method: Composition-based stats.
Identities = 67/211 (31%), Positives = 110/211 (52%), Gaps = 17/211 (8%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
LIV+D+QNDF P G+L V G+ +++ I+ LM A +V+T+DWHP+ H SFA
Sbjct: 32 ALIVIDVQNDFC-PGGALAVTDGDAIVDGINALMGQA----DAVVLTQDWHPAGHSSFAS 86
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
+H DK P+ +LWP HCV+ + G+ ++ T+ I+ K
Sbjct: 87 SHADKAPFEVTQM--------PYGAQVLWPDHCVQGSNGAAFHPRLDQ---TRADMIIRK 135
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G+ + YSAF + + T + YL ++ +VG+AL++CV +A+ AA+LG+
Sbjct: 136 GYNPAIDSYSAFFENDHKTPTGLEGYLRTRGITKLTMVGLALDFCVNFSAVDAAKLGFDV 195
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V LD R I D ++ +E + + +
Sbjct: 196 EVRLDLCRAIDLD-GSLSAAREAMTTAGVTL 225
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|YP_445581.1| pyrazinamidase/nicotinamidase [Salinibacte... 278 1e-73
ref|NP_011478.1| Nicotinamidase that converts nicotinamide ... 277 4e-73
ref|YP_002824764.1| pyrazinamidase/nicotinamidase [Rhizobiu... 277 4e-73
gb|ABB61643.1| conserved hypothetical protein [Shigella dys... 275 1e-72
gb|AAG56755.1|AE005399_9 orf, hypothetical protein [Escheri... 275 1e-72
gb|AAZ88098.1| conserved hypothetical protein [Shigella son... 275 1e-72
ref|ZP_00714471.1| COG1335: Amidases related to nicotinamid... 275 1e-72
ref|YP_403134.2| nicotinamidase/pyrazinamidase [Shigella dy... 275 2e-72
ref|ZP_02826083.1| pyrazinamidase/nicotinamidase [Escherich... 275 2e-72
ref|YP_407774.2| nicotinamidase/pyrazinamidase [Shigella bo... 275 2e-72
ref|NP_288202.2| nicotinamidase/pyrazinamidase [Escherichia... 275 2e-72
ref|YP_001743481.1| pyrazinamidase/nicotinamidase [Escheric... 273 4e-72
ref|YP_001463067.1| pyrazinamidase/nicotinamidase [Escheric... 273 4e-72
ref|ZP_00924703.1| COG1335: Amidases related to nicotinamid... 273 4e-72
ref|NP_384685.1| PROBABLE PYRAZINAMIDASE/NICOTINAMIDASE (IN... 273 5e-72
ref|ZP_00720836.1| COG1335: Amidases related to nicotinamid... 273 5e-72
ref|ZP_00999691.1| pyrazinamidase/nicotinamidase [Oceanicol... 273 6e-72
ref|ZP_00710421.1| COG1335: Amidases related to nicotinamid... 273 7e-72
ref|AP_002387.1| nicotinamidase/pyrazinamidase [Escherichia... 273 7e-72
ref|ZP_00921076.1| COG1335: Amidases related to nicotinamid... 273 7e-72
gb|AAN43052.1| orf, conserved hypothetical protein [Shigell... 273 7e-72
ref|NP_539463.1| PYRAZINAMIDASE / NICOTINAMIDASE [Brucella ... 273 8e-72
ref|ZP_00725208.1| COG1335: Amidases related to nicotinamid... 272 1e-71
ref|YP_688945.1| nicotinamidase/pyrazinamidase [Shigella fl... 272 1e-71
ref|YP_669620.1| nicotinamidase/pyrazinamidase [Escherichia... 271 2e-71
ref|YP_611664.1| Nicotinamidase [Silicibacter sp. TM1040] >... 271 2e-71
ref|ZP_01853806.1| pyrazinamidase/nicotinamidase [Planctomy... 271 2e-71
ref|YP_222148.1| PncA, pyrazinamidase/nicotinamidase [Bruce... 271 2e-71
ref|YP_001593297.1| Nicotinamidase [Brucella canis ATCC 233... 271 2e-71
ref|YP_001325893.1| Nicotinamidase [Sinorhizobium medicae W... 271 3e-71
ref|NP_105653.1| pyrazinamidase/nicotinamidase [Mesorhizobi... 271 3e-71
ref|ZP_02742886.1| nicotinamidase/pyrazinamidase [Escherich... 270 3e-71
ref|ZP_02813180.1| nicotinamidase/pyrazinamidase [Escherich... 270 4e-71
ref|YP_001628120.1| Nicotinamidase [Brucella suis ATCC 2344... 270 5e-71
ref|NP_698460.1| pyrazinamidase/nicotinamidase [Brucella su... 270 5e-71
ref|YP_675744.1| isochorismatase hydrolase [Mesorhizobium s... 270 5e-71
ref|ZP_01745842.1| pyrazinamidase/nicotinamidase [Sagittula... 270 7e-71
ref|ZP_00833121.1| COG1335: Amidases related to nicotinamid... 269 9e-71
ref|ZP_01443288.1| pyrazinamidase/nicotinamidase [Roseovari... 268 2e-70
ref|YP_001534681.1| Nicotinamidase [Dinoroseobacter shibae ... 267 4e-70
ref|ZP_01877931.1| Nicotinamidase [Roseovarius sp. TM1035] ... 267 4e-70
ref|YP_354449.1| probable pyrazinamidase/nicotinamidase [Rh... 266 7e-70
ref|ZP_00820544.1| COG1335: Amidases related to nicotinamid... 266 8e-70
ref|YP_001453362.1| hypothetical protein CKO_01797 [Citroba... 266 8e-70
ref|ZP_01015636.1| pyrazinamidase/nicotinamidase [Rhodobact... 265 1e-69
ref|YP_001478953.1| Nicotinamidase [Serratia proteamaculans... 265 2e-69
ref|YP_001041928.1| Nicotinamidase [Rhodobacter sphaeroides... 265 2e-69
ref|ZP_01902192.1| pyrazinamidase/nicotinamidase [Roseobact... 265 2e-69
ref|YP_584002.1| isochorismatase hydrolase [Ralstonia metal... 265 2e-69
ref|ZP_00825895.1| COG1335: Amidases related to nicotinamid... 265 2e-69
ref|YP_507956.1| Nicotinamidase [Jannaschia sp. CCS1] >gi|8... 264 3e-69
ref|YP_001176409.1| nicotinamidase/pyrazinamidase [Enteroba... 264 3e-69
ref|YP_001259350.1| pyrazinamidase/nicotinamidase [Brucella... 264 3e-69
ref|ZP_02152324.1| pyrazinamidase/nicotinamidase [Oceanibul... 264 4e-69
ref|YP_001708611.1| bifunctional protein [Includes: pyrazin... 263 4e-69
ref|YP_001712055.1| bifunctional protein [Includes: pyrazin... 263 4e-69
ref|ZP_02903192.1| pyrazinamidase/nicotinamidase [Escherich... 263 5e-69
ref|ZP_00829124.1| COG1335: Amidases related to nicotinamid... 263 5e-69
ref|YP_001438252.1| hypothetical protein ESA_02167 [Enterob... 263 5e-69
ref|ZP_01094319.1| pyrazinamidase/nicotinamidase [Blastopir... 263 6e-69
ref|YP_001570719.1| hypothetical protein SARI_01686 [Salmon... 263 7e-69
ref|YP_050436.1| nicotinamidase/pyrazinamidase [Erwinia car... 263 8e-69
ref|YP_001848274.1| Amidase related to nicotinamidase [Acin... 263 9e-69
ref|ZP_01756653.1| pyrazinamidase/nicotinamidase [Roseobact... 263 9e-69
ref|ZP_03830114.1| nicotinamidase/pyrazinamidase [Pectobact... 262 1e-68
ref|YP_348618.1| Nicotinamidase [Pseudomonas fluorescens Pf... 262 1e-68
ref|ZP_02061772.1| pyrazinamidase/nicotinamidase (PZAase)(N... 262 1e-68
ref|ZP_01055578.1| pyrazinamidase/nicotinamidase [Roseobact... 261 2e-68
ref|NP_460259.1| nicotinamidase/pyrazinamidase [Salmonella ... 261 2e-68
ref|ZP_00954335.1| pyrazinamidase/nicotinamidase [Sulfitoba... 261 2e-68
ref|ZP_01154749.1| pyrazinamidase/nicotinamidase [Oceanicol... 261 2e-68
ref|YP_094325.1| bifunctional pyrazinamidase/nicotinamidase... 261 2e-68
ref|YP_001588271.1| hypothetical protein SPAB_02051 [Salmon... 261 2e-68
ref|ZP_02346109.1| nicotinamidase/pyrazinamidase [Salmonell... 261 3e-68
ref|ZP_00948880.1| pyrazinamidase/nicotinamidase [Sulfitoba... 261 3e-68
ref|ZP_02146752.1| Nicotinamidase [Phaeobacter gallaeciensi... 261 3e-68
ref|YP_001370254.1| Nicotinamidase [Ochrobactrum anthropi A... 261 3e-68
ref|ZP_02669331.1| nicotinamidase/pyrazinamidase [Salmonell... 261 3e-68
ref|YP_001400957.1| pyrazinamidase/nicotinamidase [Yersinia... 261 3e-68
ref|ZP_03823780.1| nicotinamidase-like amidase [Acinetobact... 261 3e-68
ref|ZP_02568027.1| nicotinamidase/pyrazinamidase [Salmonell... 260 4e-68
ref|NP_456219.1| nicotinamidase/pyrazinamidase [Salmonella ... 260 4e-68
ref|ZP_00959572.1| pyrazinamidase/nicotinamidase [Roseovari... 260 4e-68
ref|YP_001006490.1| nicotinamidase/pyrazinamidase [Yersinia... 260 5e-68
ref|ZP_02965199.1| isochorismatase hydrolase [bacterium Ell... 260 5e-68
ref|ZP_02833934.1| nicotinamidase/pyrazinamidase [Salmonell... 260 5e-68
ref|YP_070603.1| nicotinamidase/pyrazinamidase [Yersinia ps... 259 8e-68
ref|NP_405705.1| nicotinamidase/pyrazinamidase [Yersinia pe... 259 8e-68
ref|YP_989240.1| isochorismatase family protein [Bartonella... 259 1e-67
ref|YP_032511.1| Pyrazinamidase /nicotinamidase pnca [Barto... 259 1e-67
ref|ZP_01062411.1| bifunctional pyrazinamidase/nicotinamida... 259 1e-67
ref|ZP_02362493.1| pyrazinamidase/nicotinamidase [Burkholde... 259 1e-67
ref|YP_048046.1| bifunctional protein [Includes: pyrazinami... 258 1e-67
ref|YP_001249688.1| bifunctional pyrazinamidase/nicotinamid... 258 1e-67
ref|ZP_02295815.1| Nicotinamidase [Rhizobium leguminosarum ... 258 2e-67
ref|ZP_01717575.1| pyrazinamidase/nicotinamidase [Algoripha... 258 2e-67
ref|ZP_01002009.1| pyrazinamidase/nicotinamidase [Loktanell... 258 2e-67
ref|ZP_02355353.1| pyrazinamidase/nicotinamidase [Burkholde... 258 2e-67
ref|YP_001238488.1| nicotinamidase/pyrazinamidase [Bradyrhi... 258 2e-67
ref|ZP_02151488.1| pyrazinamidase/nicotinamidase [Phaeobact... 258 2e-67
ref|ZP_03825122.1| nicotinamidase/pyrazinamidase [Pectobact... 257 3e-67
ref|YP_001334865.1| nicotinamidase and pyrazinamidase [Kleb... 257 3e-67
ref|ZP_02997772.1| hypothetical protein PROSTU_02771 [Provi... 257 4e-67
ref|NP_767317.1| bifunctional pyrazinamidase/nicotinamidase... 257 4e-67
ref|YP_001641346.1| Nicotinamidase [Methylobacterium extorq... 257 5e-67
ref|YP_768860.1| putative pyrazinamidase/nicotinamidase [Rh... 256 6e-67
ref|YP_001166243.1| Nicotinamidase [Rhodobacter sphaeroides... 256 6e-67
ref|YP_001609939.1| pyrazinamidase/nicotinamidase [Bartonel... 256 7e-67
ref|YP_001857264.1| Nicotinamidase [Burkholderia phymatum S... 256 7e-67
ref|YP_995658.1| Nicotinamidase [Verminephrobacter eiseniae... 256 8e-67
ref|ZP_03836463.1| nicotinamidase/pyrazinamidase [Citrobact... 256 9e-67
ref|YP_165367.1| pyrazinamidase/nicotinamidase [Silicibacte... 255 1e-66
gb|EEH92677.1| conserved hypothetical protein [Citrobacter ... 255 1e-66
ref|YP_001899019.1| Nicotinamidase [Ralstonia pickettii 12J... 255 1e-66
ref|YP_275215.1| pyrazinamidase/nicotinamidase [Pseudomonas... 255 1e-66
ref|YP_001817930.1| Nicotinamidase [Opitutus terrae PB90-1]... 255 1e-66
ref|YP_295620.1| Nicotinamidase [Ralstonia eutropha JMP134]... 255 2e-66
ref|ZP_01035501.1| pyrazinamidase/nicotinamidase [Roseovari... 255 2e-66
ref|ZP_02379340.1| Nicotinamidase [Burkholderia ubonensis Bu] 255 2e-66
ref|YP_125690.1| nicotinamidase/ pyrazinamidase [Legionella... 255 2e-66
ref|YP_470316.1| pyrazinamidase/nicotinamidase protein [Rhi... 255 2e-66
ref|NP_900934.1| bifunctional pyrazinamidase/nicotinamidase... 255 2e-66
ref|YP_122685.1| nicotinamidase/ pyrazinamidase [Legionella... 255 2e-66
ref|YP_216302.1| nicotinamidase/pyrazinamidase [Salmonella ... 255 2e-66
ref|ZP_02189181.1| isochorismatase hydrolase [alpha proteob... 254 3e-66
ref|XP_001912686.1| unnamed protein product [Podospora anse... 254 4e-66
ref|ZP_01740438.1| Nicotinamidase [Rhodobacterales bacteriu... 254 4e-66
ref|YP_001907502.1| Pyrazinamidase/nicotinamidase [Erwinia ... 254 4e-66
ref|NP_929791.1| nicotinamidase/pyrazinamidase [Photorhabdu... 253 5e-66
ref|NP_793078.1| pyrazinamidase/nicotinamidase [Pseudomonas... 253 5e-66
gb|EDN16169.1| pyrazinamidase/nicotinamidase [Vibrio choler... 253 6e-66
ref|YP_001204196.1| nicotinamidase/pyrazinamidase [Bradyrhi... 253 6e-66
ref|YP_033910.1| Pyrazinamidase /nicotinamidase pncA [Barto... 253 6e-66
ref|ZP_03840187.1| pyrazinamidase/nicotinamidase [Proteus m... 253 8e-66
ref|ZP_00050215.2| COG1335: Amidases related to nicotinamid... 253 8e-66
ref|YP_001808522.1| Nicotinamidase [Burkholderia ambifaria ... 253 8e-66
ref|ZP_00979781.1| COG1335: Amidases related to nicotinamid... 252 1e-65
ref|ZP_00628264.1| Nicotinamidase [Paracoccus denitrificans... 252 1e-65
ref|ZP_01749818.1| Nicotinamidase [Roseobacter sp. CCS2] >g... 252 1e-65
ref|YP_428084.1| Nicotinamidase [Rhodospirillum rubrum ATCC... 252 1e-65
ref|YP_001754321.1| Nicotinamidase [Methylobacterium radiot... 252 1e-65
ref|ZP_02010336.1| Nicotinamidase [Ralstonia pickettii 12D]... 252 1e-65
ref|YP_001821378.1| Nicotinamidase [Opitutus terrae PB90-1]... 252 1e-65
gb|ABC25334.1| pyrazinamidase/nicotinamidase [uncultured ma... 252 1e-65
ref|ZP_02854449.1| Nicotinamidase [Rhizobium leguminosarum ... 252 1e-65
ref|ZP_02911546.1| Nicotinamidase [Burkholderia ambifaria M... 252 1e-65
ref|ZP_02142971.1| pyrazinamidase/nicotinamidase [Roseobact... 252 1e-65
ref|YP_001927012.1| Nicotinamidase [Methylobacterium populi... 252 1e-65
ref|YP_369444.1| Nicotinamidase [Burkholderia sp. 383] >gi|... 252 2e-65
ref|ZP_01908379.1| nicotinamidase/pyrazinamidase [Plesiocys... 251 2e-65
ref|ZP_00416936.1| Nicotinamidase [Azotobacter vinelandii A... 251 2e-65
ref|YP_001086413.1| hypothetical protein A1S_3422 [Acinetob... 251 2e-65
ref|ZP_01675333.1| pyrazinamidase/nicotinamidase [Vibrio ch... 251 3e-65
ref|ZP_02892197.1| Nicotinamidase [Burkholderia ambifaria I... 251 3e-65
ref|YP_001765211.1| Nicotinamidase [Burkholderia cenocepaci... 251 3e-65
ref|ZP_03965982.1| nicotinamidase [Sphingobacterium spiriti... 251 3e-65
ref|ZP_01127503.1| Nicotinamidase [Nitrococcus mobilis Nb-2... 250 4e-65
ref|ZP_01945589.1| isochorismatase family protein [Coxiella... 250 4e-65
ref|YP_773783.1| Nicotinamidase [Burkholderia ambifaria AMM... 250 4e-65
ref|YP_236195.1| Nicotinamidase [Pseudomonas syringae pv. s... 250 5e-65
ref|NP_233099.1| pyrazinamidase/nicotinamidase [Vibrio chol... 250 6e-65
ref|YP_680973.1| pyrazinamidase/nicotinamidase [Roseobacter... 250 6e-65
ref|NP_519881.1| PROBABLE BIFUNCTIONAL PROTEIN: PYRAZINAMID... 250 6e-65
ref|ZP_01955355.1| pyrazinamidase/nicotinamidase [Vibrio ch... 250 6e-65
ref|XP_444840.1| hypothetical protein CAGL0A01716g [Candida... 250 6e-65
ref|YP_835549.1| Nicotinamidase [Burkholderia cenocepacia H... 250 8e-65
ref|NP_771189.1| pyrazinamidase/nicotinamidase [Bradyrhizob... 249 9e-65
ref|ZP_00945621.1| Pyrazinamidase / Nicotinamidase [Ralston... 249 1e-64
ref|YP_002756145.1| isochorismatase family protein [Acidoba... 248 1e-64
ref|YP_001236392.1| Putative pyrazinamidase/nicotinamidase ... 248 2e-64
ref|YP_001424387.1| isochorismatase family protein [Coxiell... 248 2e-64
ref|YP_626011.1| Nicotinamidase [Burkholderia cenocepacia A... 248 2e-64
ref|YP_001770067.1| Nicotinamidase [Methylobacterium sp. 4-... 248 2e-64
ref|YP_001119675.1| Nicotinamidase [Burkholderia vietnamien... 248 2e-64
ref|XP_364131.1| hypothetical protein MGG_08976 [Magnaporth... 248 3e-64
ref|ZP_01440157.1| bifunctional pyrazinamidase/nicotinamida... 247 3e-64
ref|ZP_02218673.1| isochorismatase family protein [Coxiella... 247 3e-64
ref|ZP_02055269.1| Nicotinamidase [Methylobacterium chlorom... 247 4e-64
ref|XP_001593095.1| hypothetical protein SS1G_06017 [Sclero... 247 5e-64
gb|ACO60641.1| nicotinamidase/pyrazinamidase domain-contain... 247 5e-64
ref|YP_442664.1| pyrazinamidase/nicotinamidase [Burkholderi... 246 6e-64
ref|ZP_00986621.1| COG1335: Amidases related to nicotinamid... 246 9e-64
ref|ZP_01764334.1| pyrazinamidase/nicotinamidase [Burkholde... 246 1e-63
ref|XP_001417004.1| predicted protein [Ostreococcus lucimar... 246 1e-63
ref|YP_108047.1| putative pyrazinamidase/nicotinamidase [Bu... 246 1e-63
ref|YP_863199.1| bifunctional pyrazinamidase/nicotinamidase... 245 1e-63
ref|ZP_02402385.1| pyrazinamidase/nicotinamidase [Burkholde... 245 2e-63
ref|NP_355032.2| pyrazinamidase/nicotinamidase [Agrobacteri... 245 2e-63
ref|XP_888958.1| hypothetical protein CaJ7.0402 [Candida al... 244 3e-63
ref|ZP_03850627.1| Nicotinamidase [Chryseobacterium gleum A... 244 3e-63
ref|XP_001559960.1| hypothetical protein BC1G_01519 [Botryo... 243 6e-63
ref|YP_103089.1| pyrazinamidase/nicotinamidase [Burkholderi... 243 7e-63
ref|YP_726027.1| Bifunctional Pyrazinamidase/Nicotinamidase... 241 2e-62
ref|ZP_02179817.1| pyrazinamidase/nicotinamidase [Hydrogeni... 241 3e-62
ref|YP_184063.1| probable nicotinamidase [Thermococcus koda... 240 4e-62
ref|XP_001218134.1| conserved hypothetical protein [Aspergi... 240 7e-62
ref|XP_749509.1| isochorismatase family hydrolase [Aspergi... 239 1e-61
ref|XP_456073.1| unnamed protein product [Kluyveromyces lac... 239 1e-61
gb|EDP54034.1| isochorismatase family hydrolase, putative ... 238 2e-61
ref|ZP_02120069.1| Nicotinamidase [Methylobacterium nodulan... 238 2e-61
ref|ZP_01225532.1| amidase [Aurantimonas sp. SI85-9A1] >gi|... 238 2e-61
ref|NP_126660.1| pyrazinamidase/nicotinamidase [Pyrococcus ... 238 2e-61
ref|YP_342331.1| Nicotinamidase [Nitrosococcus oceani ATCC ... 238 2e-61
ref|XP_389372.1| hypothetical protein FG09196.1 [Gibberella... 238 3e-61
ref|YP_574915.1| Nicotinamidase [Chromohalobacter salexigen... 236 6e-61
ref|YP_001415264.1| Nicotinamidase [Xanthobacter autotrophi... 236 6e-61
ref|XP_001581110.1| isochorismatase family protein [Trichom... 236 8e-61
gb|EEH61072.1| predicted protein [Micromonas pusilla CCMP1545] 236 1e-60
ref|ZP_02751610.1| nicotinamidase/pyrazinamidase [Escherich... 235 2e-60
ref|XP_964547.1| hypothetical protein NCU00713 [Neurospora ... 235 2e-60
ref|YP_001527198.1| bifunctional pyrazinamidase [Azorhizobi... 235 2e-60
ref|YP_001579554.1| Nicotinamidase [Burkholderia multivoran... 235 3e-60
ref|ZP_01252529.1| bifunctional pyrazinamidase/nicotinamida... 234 3e-60
ref|XP_458267.1| hypothetical protein DEHA0C14564g [Debaryo... 234 3e-60
ref|YP_742097.1| Nicotinamidase [Alkalilimnicola ehrlichei ... 233 5e-60
ref|NP_142913.1| pyrazinamidase/nicotinamidase [Pyrococcus ... 233 6e-60
ref|ZP_02165609.1| pyrazinamidase/nicotinamidase [Hoeflea p... 233 6e-60
ref|NP_578834.1| pyrazinamidase/nicotinamidase pxnc [Pyroco... 233 7e-60
ref|XP_001818423.1| hypothetical protein [Aspergillus oryza... 232 1e-59
ref|NP_213680.1| pyrazinamidase/nicotinamidase [Aquifex aeo... 231 2e-59
ref|XP_001391911.1| hypothetical protein An07g08360 [Asperg... 231 2e-59
ref|YP_001003310.1| Nicotinamidase [Halorhodospira halophil... 231 3e-59
ref|YP_001233233.1| Nicotinamidase [Acidiphilium cryptum JF... 230 5e-59
ref|YP_001830086.1| Nicotinamidase [Xylella fastidiosa M23]... 230 6e-59
ref|NP_779510.1| pyrazinamidase/nicotinamidase [Xylella fas... 230 6e-59
ref|XP_001829253.1| hypothetical protein CC1G_06590 [Coprin... 229 7e-59
ref|XP_001874048.1| predicted protein [Laccaria bicolor S23... 229 1e-58
ref|ZP_01644702.1| Nicotinamidase [Stenotrophomonas maltoph... 228 2e-58
ref|XP_001662895.1| pyrazinamidase/nicotinamidase [Aedes ae... 228 3e-58
ref|XP_001245038.1| hypothetical protein CIMG_04479 [Coccid... 227 3e-58
ref|XP_001184470.1| PREDICTED: similar to pyrazinamidase/ni... 227 5e-58
ref|ZP_02178583.1| pyrazinamidase/nicotinamidase [Hydrogeni... 227 5e-58
ref|XP_629052.1| nicotinamidase [Dictyostelium discoideum A... 226 9e-58
ref|XP_001201249.1| PREDICTED: similar to pyrazinamidase/ni... 226 1e-57
ref|NP_986013.1| AFR466Cp [Ashbya gossypii ATCC 10895] >gi|... 226 1e-57
ref|ZP_00650768.1| Isochorismatase hydrolase [Xylella fasti... 225 2e-57
ref|ZP_00682047.1| Isochorismatase hydrolase [Xylella fasti... 225 2e-57
ref|XP_500320.1| hypothetical protein [Yarrowia lipolytica]... 224 2e-57
ref|XP_001800076.1| hypothetical protein SNOG_09789 [Phaeos... 224 3e-57
ref|XP_001482603.1| hypothetical protein PGUG_05623 [Pichia... 224 4e-57
ref|YP_115158.1| pyrazinamidase/nicotinamidase, putative [M... 223 5e-57
ref|ZP_02324315.1| Nicotinamidase [Anaeromyxobacter dehalog... 222 1e-56
ref|XP_001859965.1| pyrazinamidase/nicotinamidase [Culex pi... 222 1e-56
ref|XP_001425684.1| hypothetical protein GSPATT00004658001 ... 221 3e-56
ref|YP_001379630.1| Nicotinamidase [Anaeromyxobacter sp. Fw... 221 3e-56
ref|XP_001385959.2| NAD(+) salvage pathway gene [Pichia sti... 221 4e-56
ref|YP_001737248.1| isochorismatase hydrolase [Candidatus K... 219 7e-56
ref|XP_321695.4| AGAP001435-PA [Anopheles gambiae str. PEST... 219 9e-56
ref|XP_973348.1| PREDICTED: similar to CG31216-PA [Triboliu... 219 1e-55
gb|ACO14708.1| Pyrazinamidase/nicotinamidase [Caligus cleme... 219 1e-55
ref|XP_001272808.1| isochorismatase family hydrolase, puta... 218 2e-55
ref|YP_865128.1| Nicotinamidase [Magnetococcus sp. MC-1] >g... 218 3e-55
ref|XP_001747826.1| predicted protein [Monosiga brevicollis... 218 3e-55
ref|XP_001032952.1| isochorismatase family protein [Tetrahy... 217 3e-55
ref|XP_001523752.1| hypothetical protein LELG_05168 [Lodder... 217 5e-55
ref|XP_001540638.1| conserved hypothetical protein [Ajellom... 217 5e-55
ref|ZP_02175503.1| Nicotinamidase [Anaeromyxobacter sp. K] ... 216 6e-55
ref|NP_953339.1| pyrazinamidase/nicotinamidase, putative [G... 216 6e-55
ref|XP_001455380.1| hypothetical protein GSPATT00002951001 ... 216 7e-55
ref|XP_001636465.1| predicted protein [Nematostella vectens... 216 1e-54
ref|XP_001671258.1| Hypothetical protein CBG01661 [Caenorha... 214 2e-54
ref|XP_967306.1| PREDICTED: similar to CG31216-PA [Triboliu... 214 2e-54
ref|NP_499876.1| Y38C1AA.3 [Caenorhabditis elegans] >gi|145... 214 2e-54
ref|ZP_01388134.1| Isochorismatase hydrolase [Geobacter sp.... 214 3e-54
ref|NP_732446.1| CG31216 CG31216-PA [Drosophila melanogaste... 214 4e-54
gb|ABV02586.1| Pyrazinamidase and nicotinamidase protein 1,... 214 4e-54
ref|YP_464529.1| Nicotinamidase [Anaeromyxobacter dehalogen... 213 5e-54
ref|YP_001230506.1| isochorismatase hydrolase [Geobacter ur... 213 8e-54
ref|ZP_02463173.1| pyrazinamidase/nicotinamidase [Burkholde... 213 9e-54
ref|YP_190619.1| Pyrazinamidase/nicotinamidase [Gluconobact... 212 1e-53
ref|YP_385324.1| Isochorismatase hydrolase [Geobacter metal... 212 1e-53
ref|XP_001708441.1| Pyrazinamidase/nicotinamidase [Giardia ... 211 2e-53
ref|YP_411601.1| Isochorismatase hydrolase [Nitrosospira mu... 211 2e-53
ref|XP_396928.2| PREDICTED: similar to CG31216-PA [Apis mel... 211 2e-53
ref|XP_001601712.1| PREDICTED: similar to LD05707p [Nasonia... 211 3e-53
ref|ZP_02984563.1| isochorismatase hydrolase [Gluconacetoba... 211 4e-53
ref|YP_522109.1| isochorismatase hydrolase [Rhodoferax ferr... 209 1e-52
ref|XP_001601573.1| PREDICTED: similar to pyrazinamidase/ni... 208 2e-52
ref|XP_624903.1| PREDICTED: similar to CG31216-PA isoform 2... 208 2e-52
ref|ZP_02530352.1| pyrazinamidase/nicotinamidase (pncA) [Bo... 208 2e-52
ref|YP_001930794.1| isochorismatase hydrolase [Sulfurihydro... 207 4e-52
ref|XP_812349.1| alpha/beta-hydrolase, putative [Trypanosom... 206 7e-52
ref|XP_567125.1| nicotinamidase [Cryptococcus neoformans va... 206 8e-52
gb|EEJ96414.1| nicotinamidase-like amidase [Thermomonospora... 203 6e-51
ref|XP_805731.1| alpha/beta-hydrolase, putative [Trypanosom... 203 9e-51
ref|NP_627144.1| nicotinamidase [Streptomyces coelicolor A3... 203 1e-50
ref|NP_216559.1| PYRAZINAMIDASE/NICOTINAMIDAS PNCA (PZase) ... 202 1e-50
ref|XP_803697.1| alpha/beta-hydrolase-like protein [Trypano... 202 1e-50
gb|AAV33185.1| pyrazinamidase [Mycobacterium tuberculosis] 201 3e-50
gb|AAV33195.1| pyrazinamidase [Mycobacterium tuberculosis] 201 3e-50
ref|ZP_02552703.1| pyrazinamidase/nicotinamidase pncA [Myco... 201 3e-50
gb|AAV33207.1| truncated pyrazinamidase [Mycobacterium tube... 201 4e-50
gb|AAV33179.1| pyrazinamidase [Mycobacterium tuberculosis] 200 5e-50
gb|AAV33181.1| pyrazinamidase [Mycobacterium tuberculosis] 200 5e-50
gb|AAV33208.1| truncated pyrazinamidase [Mycobacterium tube... 200 6e-50
gb|AAV33188.1| pyrazinamidase [Mycobacterium tuberculosis] 199 9e-50
gb|AAV33212.1| truncated pyrazinamidase [Mycobacterium tube... 199 1e-49
gb|AAV33196.1| pyrazinamidase [Mycobacterium tuberculosis] 199 1e-49
ref|NP_855719.1| PYRAZINAMIDASE/NICOTINAMIDAS PNCA (PZase) ... 199 1e-49
gb|AAV33204.1| pyrazinamidase [Mycobacterium tuberculosis] 199 1e-49
Sequences not found previously or not previously below threshold:
>ref|YP_445581.1| pyrazinamidase/nicotinamidase [Salinibacter ruber DSM 13855]
gb|ABC45428.1| pyrazinamidase/nicotinamidase [Salinibacter ruber DSM 13855]
Length = 208
Score = 278 bits (713), Expect = 1e-73, Method: Composition-based stats.
Identities = 64/214 (29%), Positives = 107/214 (50%), Gaps = 17/214 (7%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M L++VD+QNDF P G+L VP+G+ ++ ++ + + ++ T+DWHP+ H SF
Sbjct: 1 MDALLIVDLQNDFC-PGGALAVPEGDTIVPTVNAMAA----RFDHVIQTQDWHPAGHQSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
A +H D P E +LWP HCV+ T G++ + I+
Sbjct: 56 ASSHPDHAPMDVIEVD--------YGEQVLWPDHCVQGTEGAEFHPDLDTAPSE---LIL 104
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KGF + YSAF++ T + YL + D +Y+ G+A ++CVK +A+ E G+
Sbjct: 105 RKGFRPGIDSYSAFYENDGTTPTGLTGYLRERGIDTLYLCGLATDFCVKWSAVDGREEGF 164
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
V+ D TR I D + + +E+ + V+
Sbjct: 165 DVYVIEDATRGIDQDG-SLAQAWDEMNEAGVQVI 197
>ref|NP_011478.1| Nicotinamidase that converts nicotinamide to nicotinic acid as part
of the NAD(+) salvage pathway, required for life span
extension by calorie restriction; PNC1 expression
responds to all known stimuli that extend replicative
life span; Pnc1p [Saccharomyces cerevisiae]
sp|P53184|PNC1_YEAST Nicotinamidase (Nicotine deamidase) (NAMase)
pdb|2H0R|A Chain A, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|B Chain B, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|C Chain C, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|D Chain D, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|E Chain E, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|F Chain F, Structure Of The Yeast Nicotinamidase Pnc1p
pdb|2H0R|G Chain G, Structure Of The Yeast Nicotinamidase Pnc1p
emb|CAA96739.1| unnamed protein product [Saccharomyces cerevisiae]
gb|AAS56807.1| YGL037C [Saccharomyces cerevisiae]
gb|EDN61566.1| nicotinamidase [Saccharomyces cerevisiae YJM789]
Length = 216
Score = 277 bits (709), Expect = 4e-73, Method: Composition-based stats.
Identities = 216/216 (100%), Positives = 216/216 (100%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF
Sbjct: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV
Sbjct: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY
Sbjct: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK
Sbjct: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
>ref|YP_002824764.1| pyrazinamidase/nicotinamidase [Rhizobium sp. NGR234]
gb|ACP24011.1| pyrazinamidase/nicotinamidase [Rhizobium sp. NGR234]
Length = 199
Score = 277 bits (709), Expect = 4e-73, Method: Composition-based stats.
Identities = 65/212 (30%), Positives = 110/212 (51%), Gaps = 17/212 (8%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
LIV+DMQNDF P G+L V G+E++ ++ L++ A +++T+DWHP+ H SFA
Sbjct: 5 ALIVIDMQNDFC-PGGALAVAGGDEIVPVVNSLIEKA----KHVILTQDWHPAGHSSFAS 59
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
+H K P+ T T E LWP HCV+ + G+ + T ++ K
Sbjct: 60 SHPGKAPFQTVTM--------PYGEQTLWPDHCVQGSPGADFHPALR---WTTAELVIRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF T + YSAF + + T + YL + +V + G+A ++CV +A+ A G+ T
Sbjct: 109 GFRTGIDSYSAFFENDHRTPTGLAGYLRERGISKVSLCGLATDFCVAFSALDAVAEGFST 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
+V+LD R I + + + ++ + ++
Sbjct: 169 SVVLDACRGIDLNG-SLAAMTRRMRDAGVELI 199
>gb|ABB61643.1| conserved hypothetical protein [Shigella dysenteriae Sd197]
Length = 219
Score = 275 bits (705), Expect = 1e-72, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDQEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>gb|AAG56755.1|AE005399_9 orf, hypothetical protein [Escherichia coli O157:H7 EDL933]
dbj|BAB35898.1| hypothetical protein [Escherichia coli O157:H7 str. Sakai]
Length = 219
Score = 275 bits (705), Expect = 1e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>gb|AAZ88098.1| conserved hypothetical protein [Shigella sonnei Ss046]
Length = 219
Score = 275 bits (705), Expect = 1e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|ZP_00714471.1| COG1335: Amidases related to nicotinamidase [Escherichia coli B7A]
gb|ABB65946.1| conserved hypothetical protein [Shigella boydii Sb227]
Length = 219
Score = 275 bits (705), Expect = 1e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ + + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVEVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|YP_403134.2| nicotinamidase/pyrazinamidase [Shigella dysenteriae Sd197]
Length = 213
Score = 275 bits (703), Expect = 2e-72, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDQEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|ZP_02826083.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str. EC508]
Length = 213
Score = 275 bits (703), Expect = 2e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_407774.2| nicotinamidase/pyrazinamidase [Shigella boydii Sb227]
ref|YP_001880565.1| pyrazinamidase/nicotinamidase [Shigella boydii CDC 3083-94]
gb|ACD08036.1| pyrazinamidase/nicotinamidase [Shigella boydii CDC 3083-94]
Length = 213
Score = 275 bits (703), Expect = 2e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ + + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVEVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|NP_288202.2| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 EDL933]
ref|YP_310333.2| nicotinamidase/pyrazinamidase [Shigella sonnei Ss046]
ref|NP_310502.2| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str. Sakai]
ref|ZP_02787166.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4501]
ref|YP_001724839.1| Nicotinamidase [Escherichia coli ATCC 8739]
gb|ACA77512.1| Nicotinamidase [Escherichia coli ATCC 8739]
Length = 213
Score = 275 bits (703), Expect = 2e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_001743481.1| pyrazinamidase/nicotinamidase [Escherichia coli SMS-3-5]
gb|ACB19609.1| pyrazinamidase/nicotinamidase [Escherichia coli SMS-3-5]
Length = 213
Score = 273 bits (700), Expect = 4e-72, Method: Composition-based stats.
Identities = 68/212 (32%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLKQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ I+G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTALDDWLRDHEIDELIIMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_001463067.1| pyrazinamidase/nicotinamidase [Escherichia coli E24377A]
gb|ABV17497.1| pyrazinamidase/nicotinamidase [Escherichia coli E24377A]
Length = 213
Score = 273 bits (700), Expect = 4e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|ZP_00924703.1| COG1335: Amidases related to nicotinamidase [Escherichia coli
101-1]
Length = 219
Score = 273 bits (700), Expect = 4e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLHQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|NP_384685.1| PROBABLE PYRAZINAMIDASE/NICOTINAMIDASE (INCLUDES: PYRAZINAMIDASE,
NICOTINAMIDASE) PROTEIN [Sinorhizobium meliloti 1021]
gb|AAF76877.1|AF247710_2 putative pyrazinamidase/nicotinamidase PncA [Sinorhizobium
meliloti]
emb|CAC45151.1| Probable pyrazinamidase/nicotinamidase (includes: pyrazinamidase,
nicotinamidase) [Sinorhizobium meliloti 1021]
Length = 211
Score = 273 bits (700), Expect = 5e-72, Method: Composition-based stats.
Identities = 62/213 (29%), Positives = 105/213 (49%), Gaps = 17/213 (7%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ LIV+DMQNDF P G+L V G+E++ ++ L+ + +V+T+DWHP+ H SFA
Sbjct: 16 EALIVIDMQNDFC-PGGALAVEGGDEIVPAVNRLIDASP----HVVLTQDWHPAGHSSFA 70
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H K P+ T E LWP HCV+ + G+ + T ++
Sbjct: 71 STHPGKAPFQTVAM--------PYGEQTLWPEHCVQGSAGADFHPSLR---WTSAELVIR 119
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + + YSAF + + T + YL + V + G+A ++CV +A+ A G+
Sbjct: 120 KGFRREIDSYSAFFENDHRTPTGLAGYLRERGIRSVTLCGLATDFCVAFSALDAVAKGFS 179
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
T+V+L R I + + ++ + ++
Sbjct: 180 TSVVLGACRGIDLNGSLAAMTLR-MRDAGVRLI 211
>ref|ZP_00720836.1| COG1335: Amidases related to nicotinamidase [Escherichia coli
E110019]
ref|ZP_00727864.1| COG1335: Amidases related to nicotinamidase [Escherichia coli E22]
Length = 219
Score = 273 bits (700), Expect = 5e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQHC-VEPYM--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|ZP_00999691.1| pyrazinamidase/nicotinamidase [Oceanicola batsensis HTCC2597]
gb|EAQ03265.1| pyrazinamidase/nicotinamidase [Oceanicola batsensis HTCC2597]
Length = 198
Score = 273 bits (699), Expect = 6e-72, Method: Composition-based stats.
Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 17/212 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L+V+D+QNDF P G+L V G+ ++ I+ LM + + +V+T+DWHP+ H SFA
Sbjct: 3 RALLVIDVQNDFC-PGGALAVNGGDTIVPGINQLMTE----FDAVVLTQDWHPAGHSSFA 57
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H+ KEP +LWP HC++ + G+Q + + I+
Sbjct: 58 SSHEGKEPMEMTEM--------PYGPQVLWPDHCIQGSHGAQFHPDLTT---DRADLIIR 106
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + YSAF + + T + YL +++ +VG+A ++CV +A+ AA+LG+
Sbjct: 107 KGFDPAIDSYSAFFENDHETPTGLEGYLRTRGIEDLTLVGLATDFCVNFSAVDAAKLGFG 166
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
TV D R I + + E + +
Sbjct: 167 VTVRTDLCRAIDLNG-SLQAALEGMTQAGAGI 197
>ref|ZP_00710421.1| COG1335: Amidases related to nicotinamidase [Escherichia coli B171]
Length = 219
Score = 273 bits (698), Expect = 7e-72, Method: Composition-based stats.
Identities = 68/212 (32%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY PG WPVHCV+N+ G+QL + + + +
Sbjct: 69 SQHC-VEPYM--------PGQLDGLPQTFWPVHCVQNSEGAQLHPLLNQKAIAA---MFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|AP_002387.1| nicotinamidase/pyrazinamidase [Escherichia coli W3110]
ref|NP_416282.4| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr.
MG1655]
ref|YP_001458548.1| pyrazinamidase/nicotinamidase [Escherichia coli HS]
ref|YP_001730745.1| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr.
DH10B]
ref|ZP_02999827.1| pyrazinamidase/nicotinamidase [Escherichia coli 53638]
sp|P21369|PNCA_ECOLI Pyrazinamidase/nicotinamidase (PZAase) (Nicotine deamidase)
(NAMase)
gb|AAA23447.1| ORF1
dbj|BAA15559.1| nicotinamidase/pyrazinamidase [Escherichia coli W3110]
gb|AAC74838.2| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr.
MG1655]
gb|ABV06165.1| pyrazinamidase/nicotinamidase [Escherichia coli HS]
gb|ACB02967.1| nicotinamidase/pyrazinamidase [Escherichia coli str. K-12 substr.
DH10B]
gb|EDU62859.1| pyrazinamidase/nicotinamidase [Escherichia coli 53638]
Length = 213
Score = 273 bits (698), Expect = 7e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLHQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|ZP_00921076.1| COG1335: Amidases related to nicotinamidase [Shigella dysenteriae
1012]
Length = 219
Score = 273 bits (698), Expect = 7e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHTFVEMSAAGATL 208
>gb|AAN43052.1| orf, conserved hypothetical protein [Shigella flexneri 2a str. 301]
gb|AAP16947.1| hypothetical protein S1570 [Shigella flexneri 2a str. 2457T]
Length = 219
Score = 273 bits (698), Expect = 7e-72, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ + + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVEVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLGGLRQTFWPEHCVQNSEGAQLHPLLNQKEIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTALDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|NP_539463.1| PYRAZINAMIDASE / NICOTINAMIDASE [Brucella melitensis 16M]
gb|AAL51727.1| PYRAZINAMIDASE / NICOTINAMIDASE [Brucella melitensis 16M]
Length = 251
Score = 273 bits (698), Expect = 8e-72, Method: Composition-based stats.
Identities = 66/214 (30%), Positives = 117/214 (54%), Gaps = 17/214 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+V+D+QNDF P G+L V +G+E+I ++ L+ +++ +VVT+DWHP+ H SFA
Sbjct: 47 ALVVIDVQNDFC-PGGALAVERGDEIIPIVNRLIGESEN----VVVTQDWHPANHSSFAS 101
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
NH P+ T +LWP HCV+N+ G++ + + +V K
Sbjct: 102 NHSGSRPFDTVNMS--------YGPQVLWPDHCVQNSEGAEFHPDLQWW---RAQLVVRK 150
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF + YSAF + + T + YL + + + +VG+A ++CV ++A+ A + G++
Sbjct: 151 GFRIGIDSYSAFFENDHCTPTGLGGYLRERNIGSLTMVGLATDFCVASSALDAVQQGFQV 210
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I + +N + E++K + ++D+
Sbjct: 211 RVRLDACRGIDLNG-SMNIMLEKMKQAGVELIDE 243
>ref|ZP_00725208.1| COG1335: Amidases related to nicotinamidase [Escherichia coli F11]
ref|YP_852852.1| nicotinamidase/pyrazinamidase [Escherichia coli APEC O1]
gb|AAN80631.1|AE016761_206 Pyrazinamidase/nicotinamidase [Escherichia coli CFT073]
gb|ABE07440.1| pyrazinamidase/nicotinamidase [Escherichia coli UTI89]
gb|ABJ01138.1| pyrazinamidase/nicotinamidase [Escherichia coli APEC O1]
Length = 219
Score = 272 bits (697), Expect = 1e-71, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 10 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 68
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 69 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLKQKAIAA---VFH 116
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H +E+ ++G+A +YCVK T + A +LGYK
Sbjct: 117 KGENPLVDSYSAFFDNGRRQKTALDDWLRAHVINELIVMGLATDYCVKFTVLDALQLGYK 176
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 177 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 208
>ref|YP_688945.1| nicotinamidase/pyrazinamidase [Shigella flexneri 5 str. 8401]
ref|NP_707345.2| nicotinamidase/pyrazinamidase [Shigella flexneri 2a str. 301]
ref|NP_837140.2| nicotinamidase/pyrazinamidase [Shigella flexneri 2a str. 2457T]
gb|ABF03640.1| conserved hypothetical protein [Shigella flexneri 5 str. 8401]
Length = 213
Score = 272 bits (696), Expect = 1e-71, Method: Composition-based stats.
Identities = 67/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ + + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVEVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLGGLRQTFWPEHCVQNSEGAQLHPLLNQKEIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTALDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_669620.1| nicotinamidase/pyrazinamidase [Escherichia coli 536]
ref|NP_754066.2| nicotinamidase/pyrazinamidase [Escherichia coli CFT073]
ref|YP_540971.2| nicotinamidase/pyrazinamidase [Escherichia coli UTI89]
gb|ABG69719.1| pyrazinamidase/nicotinamidase [Escherichia coli 536]
Length = 213
Score = 271 bits (695), Expect = 2e-71, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 109/212 (51%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLKQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H +E+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTALDDWLRAHVINELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_611664.1| Nicotinamidase [Silicibacter sp. TM1040]
gb|ABF62402.1| Nicotinamidase [Silicibacter sp. TM1040]
Length = 201
Score = 271 bits (695), Expect = 2e-71, Method: Composition-based stats.
Identities = 61/212 (28%), Positives = 108/212 (50%), Gaps = 18/212 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L+V+D+QNDF P G+L V +G+E++ PI+ +M+ + +++T+DWHP H SFA
Sbjct: 7 QALLVIDVQNDFC-PGGALAVTEGDEVVAPINAMME----RFDTVILTQDWHPKGHSSFA 61
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H P+ T + ++WP HCV+ + G++ ++ T I+
Sbjct: 62 SSHPGHAPFDTMEM--------YYGQQVMWPDHCVQGSQGAEFHPRLR----TDGDMIIR 109
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + + YSAF + T + YL ++ +VG+A ++CV +A+ A LG+
Sbjct: 110 KGFRPEVDSYSAFFENDQTTPTGLEGYLRTRGISDLTLVGLATDFCVAFSALDARRLGFS 169
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V L R I D + E ++ + +
Sbjct: 170 VEVELAACRAIDLDG-SLATQLENMRQKGVKI 200
>ref|ZP_01853806.1| pyrazinamidase/nicotinamidase [Planctomyces maris DSM 8797]
gb|EDL60134.1| pyrazinamidase/nicotinamidase [Planctomyces maris DSM 8797]
Length = 199
Score = 271 bits (695), Expect = 2e-71, Method: Composition-based stats.
Identities = 71/215 (33%), Positives = 122/215 (56%), Gaps = 16/215 (7%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M+ LI+VD+Q DF+ P GSL VP+G++++ ++LM D+ +V T+DWHP+ H+SF
Sbjct: 1 MRALILVDLQYDFM-PGGSLAVPEGDQVVPIANELM----SDFDLVVATQDWHPADHLSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
A H D+E D + E ILWP HCV+ T G++L + + +I
Sbjct: 56 ASQHPDREIGEQI--------DLAGLEQILWPDHCVQGTRGAELHADLKQNQL---DRIF 104
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KG + YS F+D + T M +YL++ V ++G+A +YCVK TA+ A +LG+
Sbjct: 105 PKGTDRLIDSYSGFYDNGHQKSTGMGEYLKEQGVQSVTVLGLAADYCVKWTALDAVKLGF 164
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
+T++ L R + P +++ +E++ + +++
Sbjct: 165 QTSLSLRGCRGVDLSPGDVHRAYQEMQNAGVEIIE 199
>ref|YP_222148.1| PncA, pyrazinamidase/nicotinamidase [Brucella abortus biovar 1 str.
9-941]
ref|YP_414852.1| Isochorismatase hydrolase family [Brucella melitensis biovar
Abortus 2308]
ref|YP_001935354.1| Isochorismatase hydrolase family [Brucella abortus S19]
gb|AAX74787.1| PncA, pyrazinamidase/nicotinamidase [Brucella abortus biovar 1 str.
9-941]
emb|CAJ11440.1| Isochorismatase hydrolase family [Brucella melitensis biovar
Abortus 2308]
gb|ACD72880.1| Isochorismatase hydrolase family [Brucella abortus S19]
Length = 209
Score = 271 bits (695), Expect = 2e-71, Method: Composition-based stats.
Identities = 66/214 (30%), Positives = 118/214 (55%), Gaps = 17/214 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+V+D+QNDF P G+L V +G+E+I ++ L+ ++++ +VVT+DWHP+ H SFA
Sbjct: 5 ALVVIDVQNDFC-PGGALAVERGDEIIPIVNRLIGESEK----VVVTQDWHPANHSSFAS 59
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
NH P+ T +LWP HCV+N+ G++ + + +V K
Sbjct: 60 NHSGSRPFDTVNMS--------YGPQVLWPDHCVQNSEGAEFHPDLQWW---RAQLVVRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF + YSAF + + T + YL + + + +VG+A ++CV ++A+ A + G++
Sbjct: 109 GFRIGIDSYSAFFENDHCTPTGLGGYLRERNIGSLTMVGLATDFCVASSALDAVQQGFQV 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I + +N + E++K + ++D+
Sbjct: 169 RVRLDACRGIDLNG-SMNIMLEKMKQAGVELIDE 201
>ref|YP_001593297.1| Nicotinamidase [Brucella canis ATCC 23365]
gb|ABX62526.1| Nicotinamidase [Brucella canis ATCC 23365]
Length = 209
Score = 271 bits (694), Expect = 2e-71, Method: Composition-based stats.
Identities = 65/214 (30%), Positives = 115/214 (53%), Gaps = 17/214 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+V+D+QNDF P G+L V +G+E+I ++ L+ +++ +VVT+DWHP+ H SFA
Sbjct: 5 ALVVIDVQNDFC-PGGALAVERGDEIIPIVNRLIGESEN----VVVTQDWHPANHSSFAS 59
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
NH P+ T +LWP HCV+N+ G++ + + +V K
Sbjct: 60 NHPGSRPFDTVNMS--------YGPQVLWPDHCVQNSEGAEFHPDLQWW---RAQLVVRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G + YSAF + + T + YL + + + +VG+A ++CV +A+ A + G++
Sbjct: 109 GVRIGIDSYSAFFENDHCTPTGLGGYLRERNIGSLTMVGLATDFCVACSALDAVQQGFQV 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I + +N + E++K + ++D+
Sbjct: 169 RVRLDACRGIDLNG-SMNIMLEKMKQAGVELIDE 201
>ref|YP_001325893.1| Nicotinamidase [Sinorhizobium medicae WSM419]
gb|ABR59058.1| Nicotinamidase [Sinorhizobium medicae WSM419]
Length = 199
Score = 271 bits (693), Expect = 3e-71, Method: Composition-based stats.
Identities = 63/212 (29%), Positives = 108/212 (50%), Gaps = 17/212 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ LIV+DMQNDF P G+L V G+E+I ++ L++ + +V+T+DWHP+ H SFA
Sbjct: 4 EALIVIDMQNDFC-PGGALAVDGGDEIIPAVNRLIETSP----HVVLTQDWHPADHSSFA 58
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H + + T T E LWP HCV+ + G+ + T ++
Sbjct: 59 SSHPGRLAFQTVTM--------PYGEQTLWPAHCVQASVGADFHPSLR---WTSAELVIR 107
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + + YSAF + + T + YL + V + G+A ++CV +A+ A G+
Sbjct: 108 KGFRREIDSYSAFFENDHRTPTGLAGYLRERGISSVTLCGLATDFCVAFSALDAVAQGFS 167
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
T+V+LD R I+ + + ++ + +
Sbjct: 168 TSVVLDACRGINLNGSLAAMTFR-MRDAGVRL 198
>ref|NP_105653.1| pyrazinamidase/nicotinamidase [Mesorhizobium loti MAFF303099]
dbj|BAB51439.1| pyrazinamidase/nicotinamidase [Mesorhizobium loti MAFF303099]
Length = 204
Score = 271 bits (693), Expect = 3e-71, Method: Composition-based stats.
Identities = 66/214 (30%), Positives = 112/214 (52%), Gaps = 17/214 (7%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L+V+D+QNDF P G+L V G+E++ ++D++ R +V+T+DWHP+ H SFA
Sbjct: 4 QALVVIDLQNDFC-PGGALAVTGGDEIVPLVNDMI----RRTDHVVLTQDWHPAGHSSFA 58
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H +P++ + LWP HC++ + GS + TK ++
Sbjct: 59 SSHPGAQPFTMIEM--------PYGQQTLWPDHCIQGSLGSDFHSGLA---WTKAELVIR 107
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF D + YSAF + + T + YL + D V +VG+A ++CV +A+ A G+K
Sbjct: 108 KGFRPDIDSYSAFFENDHTTPTGLGGYLRERGIDTVTLVGLATDFCVGFSALDAVSQGFK 167
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
TTV LD R I + + + ++ + + D
Sbjct: 168 TTVRLDACRGIDLNG-SLEAMLRRMRDAGVALED 200
>ref|ZP_02742886.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4045]
ref|ZP_02768554.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4115]
ref|ZP_02774431.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4113]
ref|ZP_02781786.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4401]
ref|ZP_02795740.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4486]
ref|ZP_02799931.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4196]
ref|ZP_02807199.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4076]
ref|ZP_02818179.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str.
EC4042]
gb|EDU33244.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4196]
gb|EDU54343.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4113]
gb|EDU69221.1| pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str.
EC4076]
Length = 213
Score = 270 bits (692), Expect = 3e-71, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSA D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSALFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSAHAFMEMSAAGATL 202
>ref|ZP_02813180.1| nicotinamidase/pyrazinamidase [Escherichia coli O157:H7 str. EC869]
Length = 213
Score = 270 bits (692), Expect = 4e-71, Method: Composition-based stats.
Identities = 66/212 (31%), Positives = 108/212 (50%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H EPY+ PG WP HCV+N+ G+QL + + + +
Sbjct: 63 SQH-GVEPYT--------PGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQKAIAA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L H DE+ ++G+A +YCVK T + A +LGYK
Sbjct: 111 KGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYK 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D ++ P+ E+ A +
Sbjct: 171 VNVITDGCHGVNIQPQDSAHAFMEMSAAGATL 202
>ref|YP_001628120.1| Nicotinamidase [Brucella suis ATCC 23445]
gb|ABY38550.1| Nicotinamidase [Brucella suis ATCC 23445]
Length = 209
Score = 270 bits (691), Expect = 5e-71, Method: Composition-based stats.
Identities = 65/214 (30%), Positives = 116/214 (54%), Gaps = 17/214 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+V+D+QNDF P G+L V +G+E+I ++ L+ +++ +VVT+DWHP+ H SFA
Sbjct: 5 ALVVIDVQNDFC-PGGALAVERGDEIIPIVNRLIGESEN----VVVTQDWHPANHSSFAS 59
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
NH P+ T +LWP HCV+N+ G++ + + +V K
Sbjct: 60 NHPGSRPFDTVNMS--------YGPQVLWPDHCVQNSEGAEFHPDLQWW---RAQLVVRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G + YSAF + + T + YL + + + +VG+A ++CV ++A+ A + G++
Sbjct: 109 GVRIGCDSYSAFFENDHCTPTGLGGYLRERNIGSLTMVGLATDFCVASSALDAVQQGFQV 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I + +N + E++K + ++D+
Sbjct: 169 RVRLDACRGIDLNG-SMNIMLEKMKQAGVELIDE 201
>ref|NP_698460.1| pyrazinamidase/nicotinamidase [Brucella suis 1330]
gb|AAN30375.1| pyrazinamidase/nicotinamidase [Brucella suis 1330]
Length = 209
Score = 270 bits (691), Expect = 5e-71, Method: Composition-based stats.
Identities = 64/214 (29%), Positives = 116/214 (54%), Gaps = 17/214 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+V+D+QNDF P G+L + +G+E+I ++ L+ +++ +VVT+DWHP+ H SFA
Sbjct: 5 ALVVIDVQNDFC-PGGALAIERGDEIIPIVNRLIGESEN----VVVTQDWHPANHSSFAS 59
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
NH P+ T +LWP HCV+N+ G++ + + +V K
Sbjct: 60 NHPGSRPFDTVNMS--------YGPQVLWPDHCVQNSEGAEFHPDLQWW---RAQLVVRK 108
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G + YSAF + + T + YL + + + +VG+A ++CV ++A+ A + G++
Sbjct: 109 GVHIGIDSYSAFFENDHCTPTGLGGYLRERNIGSLTMVGLATDFCVASSALDAVQQGFQV 168
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVDK 216
V LD R I + +N + E++K + ++D+
Sbjct: 169 RVRLDACRGIDLNG-SMNIMLEKMKQAGVELIDE 201
>ref|YP_675744.1| isochorismatase hydrolase [Mesorhizobium sp. BNC1]
gb|ABG64579.1| isochorismatase hydrolase [Mesorhizobium sp. BNC1]
Length = 203
Score = 270 bits (691), Expect = 5e-71, Method: Composition-based stats.
Identities = 66/213 (30%), Positives = 113/213 (53%), Gaps = 17/213 (7%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ LIV+D+QNDF P G+L V +G+E++ ++ L+Q + +++T+DWHP+ H SFA
Sbjct: 8 EALIVIDVQNDFC-PGGALAVERGDEVVPVVNGLIQ----RFDHVILTQDWHPAGHSSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+ K P+ T E LWP HCV+ T G+ + TK ++
Sbjct: 63 SSQPGKAPFETVLM--------PYGEQTLWPDHCVQGTSGADFHPGLE---WTKAELVIR 111
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + + YSAF + + T ++ YL + +V + G+A ++CV +A+ A G++
Sbjct: 112 KGFRSAIDSYSAFFENDHETPTGLSGYLRERGIGKVTLAGLATDFCVAYSALDARRQGFE 171
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
TV+L+ R I + + E +KA + +V
Sbjct: 172 ATVILEACRAIDL-GGSLAVMTERMKAAGVELV 203
>ref|ZP_01745842.1| pyrazinamidase/nicotinamidase [Sagittula stellata E-37]
gb|EBA08464.1| pyrazinamidase/nicotinamidase [Sagittula stellata E-37]
Length = 197
Score = 270 bits (690), Expect = 7e-71, Method: Composition-based stats.
Identities = 67/213 (31%), Positives = 110/213 (51%), Gaps = 17/213 (7%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M LIV+D+QNDF P G+L V +G+E++ PI+ LM + + +V+T+DWHP+ H SF
Sbjct: 1 MHALIVIDVQNDFC-PGGALAVAQGDEIVQPINALMAE----FDAVVLTQDWHPAGHSSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
A H+ K P+ D +LWP HC++ + G+ ++ + I+
Sbjct: 56 ASAHEGKAPFEMI--------DMPYGPQVLWPDHCIQASPGANFHMELET---DRADLII 104
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KGF + + YSAF + + T + YL D + +VG+A ++CV +A+ AA LG+
Sbjct: 105 RKGFRSAIDSYSAFFENDHTTPTGLEGYLRTRGIDRLTLVGLATDFCVNYSAVDAARLGF 164
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V D R I D + +E + + +
Sbjct: 165 SVAVREDLCRAIDLDG-SLKAARESMMQAGVTL 196
>ref|ZP_00833121.1| COG1335: Amidases related to nicotinamidase [Yersinia intermedia
ATCC 29909]
Length = 216
Score = 269 bits (689), Expect = 9e-71, Method: Composition-based stats.
Identities = 62/211 (29%), Positives = 105/211 (49%), Gaps = 13/211 (6%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+++D+QNDF P G+L V +G+++I + + ++ ++DWHP+ H SFA
Sbjct: 4 ALLLIDLQNDFC-PGGALAVAEGDQVIAIANQAIDVCLSKKIPVIASQDWHPAEHRSFAI 62
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
N S G+ + + WP+HCV+N G+ L Q+ + I K
Sbjct: 63 NSN---------AESGTVGELNGLPQVWWPMHCVQNESGAALHPQLKQNAIEA---IFRK 110
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G D + YSAF D KT ++ +L++ ++I+G+A +YCVK + + A LGY+T
Sbjct: 111 GQDPDIDSYSAFFDNGRRAKTPLDGWLQQQGIHRLFIMGLATDYCVKYSVLDALSLGYQT 170
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINV 213
TV+ D R ++ P + N+
Sbjct: 171 TVISDGCRGVNLQPHDSQHALNSMSKAGANL 201
>ref|ZP_01443288.1| pyrazinamidase/nicotinamidase [Roseovarius sp. HTCC2601]
gb|EAU46422.1| pyrazinamidase/nicotinamidase [Roseovarius sp. HTCC2601]
Length = 197
Score = 268 bits (687), Expect = 2e-70, Method: Composition-based stats.
Identities = 62/213 (29%), Positives = 105/213 (49%), Gaps = 17/213 (7%)
Query: 1 MKTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISF 60
M L+V+D+QNDF P G+L V G+E++ PI+ +M + + +++T+DWHP+ H SF
Sbjct: 1 MHALVVIDVQNDFC-PGGALAVTGGDEIVAPINAMMAE----FDAVILTQDWHPAGHSSF 55
Query: 61 AKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIV 120
A H K P +LWP HCV+ + G+ ++ + I+
Sbjct: 56 ASQHPGKAPLEMTEM--------PYGPQVLWPDHCVQGSLGAAFHPRLDT---DRAELII 104
Query: 121 DKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGY 180
KGF + YSAF + + T + YL D + +VG+A ++CV +A+ AA LG+
Sbjct: 105 RKGFRPGIDSYSAFFENDHETPTGLEGYLRTRGIDRLTLVGLATDFCVNFSAVDAATLGF 164
Query: 181 KTTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
+ TV R I + + ++ + +
Sbjct: 165 EVTVREAACRGIDL-GGSLAVARAGMQEAGVTL 196
>ref|YP_001534681.1| Nicotinamidase [Dinoroseobacter shibae DFL 12]
gb|ABV95080.1| Nicotinamidase [Dinoroseobacter shibae DFL 12]
Length = 200
Score = 267 bits (683), Expect = 4e-70, Method: Composition-based stats.
Identities = 68/213 (31%), Positives = 107/213 (50%), Gaps = 17/213 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
LIV+D+QNDF P G+L V +G ++ I+ LM +A +V+T+DWHP+ H SFA
Sbjct: 4 ALIVIDVQNDFC-PGGALAVAEGNTIVPAINALMAEA----EAVVLTQDWHPAGHSSFAS 58
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
+H P S D +LWP HCV+ + G+ + T+ IV K
Sbjct: 59 SHPGAAPLSMI--------DMPYGPQVLWPDHCVQGSDGAAFHPDLDT---TRADMIVRK 107
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF + YSAF + + T ++ YL ++ +VG+A ++CV +A+ AA+LG+
Sbjct: 108 GFRPAIDSYSAFFENDHETPTGLDGYLRSRGITDLTLVGLATDFCVHYSAVDAAKLGFAV 167
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
TV D R I D + ++ + + D
Sbjct: 168 TVRTDLCRAIDLDG-SLASACTAMQEAGVRLSD 199
>ref|ZP_01877931.1| Nicotinamidase [Roseovarius sp. TM1035]
gb|EDM33315.1| Nicotinamidase [Roseovarius sp. TM1035]
Length = 198
Score = 267 bits (683), Expect = 4e-70, Method: Composition-based stats.
Identities = 64/212 (30%), Positives = 108/212 (50%), Gaps = 17/212 (8%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
LIV+D+QNDF P G+L VP+G++++ I+ LM + +++T+DWHPS H SFA
Sbjct: 4 ALIVIDLQNDFC-PGGALAVPEGDQIVPGINALMPEFPA----VILTQDWHPSGHSSFAS 58
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
+H K Y +LWP HCV+ + G+ + + I+ K
Sbjct: 59 SHPGKSAYEMTEM--------PYGPQVLWPDHCVQGSHGAAFHQDLNTA---RADLILRK 107
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G+ + YSAF + T ++ YL+ ++ +VG+A ++CV +A+ AA LGY+
Sbjct: 108 GYNPAIDSYSAFFENDRATPTGLHGYLQTRGITDLTMVGLATDFCVNYSALDAARLGYRV 167
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
TV D R I + + + + A + ++
Sbjct: 168 TVRRDLARGIDL-GGSLAEAEAGMTAAGVTLL 198
>ref|YP_354449.1| probable pyrazinamidase/nicotinamidase [Rhodobacter sphaeroides
2.4.1]
gb|ABA80548.1| probable pyrazinamidase/nicotinamidase [Rhodobacter sphaeroides
2.4.1]
Length = 201
Score = 266 bits (681), Expect = 7e-70, Method: Composition-based stats.
Identities = 62/212 (29%), Positives = 103/212 (48%), Gaps = 18/212 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ LIV+D+QNDF P G+L V G+ +I I+ L+ + + T+DWHP+ H SFA
Sbjct: 6 EALIVIDVQNDFC-PGGALAVAGGDAIIPRINALLPEFGAR----IFTQDWHPADHSSFA 60
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H+ P+S +LWP HCV+ T G++ + ++
Sbjct: 61 STHE-AVPFSLIEM--------PYGPQVLWPTHCVQGTRGAEFHPALETAP---ADLVLR 108
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF D + YSAF + T + YL + V + G+A ++CV +A+ AA LG++
Sbjct: 109 KGFRRDIDSYSAFFENDRTTPTGLEGYLRSRGIEAVTLAGLATDFCVAYSALDAARLGFR 168
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
TVL + I + + +K ++ + +
Sbjct: 169 VTVLEGASAAIDLNG-SLAAIKAQMAEAGVAL 199
>ref|ZP_00820544.1| COG1335: Amidases related to nicotinamidase [Yersinia bercovieri
ATCC 43970]
Length = 216
Score = 266 bits (681), Expect = 8e-70, Method: Composition-based stats.
Identities = 63/211 (29%), Positives = 109/211 (51%), Gaps = 13/211 (6%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+++D+QNDF P G+L V +G+ +I + + + ++ ++DWHP+ H SFA
Sbjct: 4 ALLLIDLQNDFC-PGGALAVTEGDRVIAVANQAINACLQQQIAVIASQDWHPADHRSFAI 62
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
N GD + + WPVHCV++T G+ Q+ + +T K
Sbjct: 63 NSNAVP---------GTIGDLNGLPQVWWPVHCVQHTPGADWHPQLQQEAITA---TFRK 110
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G D + YSAF D KT ++ +L++ D +YI+G+A +YCVK + + A LGY+T
Sbjct: 111 GQDPDVDSYSAFFDNGRRSKTALDDWLQQQGIDRLYIMGLATDYCVKYSVLDALSLGYQT 170
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINV 213
TV+ D R ++ P+ + + + ++
Sbjct: 171 TVISDGCRGVNLQPQDSQQAFDVMSKAGADL 201
>ref|YP_001453362.1| hypothetical protein CKO_01797 [Citrobacter koseri ATCC BAA-895]
gb|ABV12926.1| hypothetical protein CKO_01797 [Citrobacter koseri ATCC BAA-895]
Length = 213
Score = 266 bits (681), Expect = 8e-70, Method: Composition-based stats.
Identities = 61/212 (28%), Positives = 105/212 (49%), Gaps = 13/212 (6%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ L++VD+QNDF + G+L VP+G+ ++ + L+ ++ ++DWHP+ H SFA
Sbjct: 4 RALLLVDLQNDFCA-GGALAVPEGDSTVDVANRLIAWCKARGDTVIASQDWHPAGHGSFA 62
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H+ +PYS G WP HCV+N+ G+ L + + +
Sbjct: 63 SQHQ-AQPYSQ--------GQLDGLAQTFWPDHCVQNSDGAALHPLLRQNAIDA---VFH 110
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KG + YSAF D KT ++ +L ++ + ++G+A +YCVK T + A +LGY
Sbjct: 111 KGENPQVDSYSAFFDNGRRQKTALDAWLRENGVQTLIVMGLATDYCVKFTVLDALQLGYT 170
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V+ D R ++ P+ E+ A +
Sbjct: 171 VNVITDGCRGVNIQPQDSTHAFMEMAAAGATL 202
>ref|ZP_01015636.1| pyrazinamidase/nicotinamidase [Rhodobacterales bacterium HTCC2654]
gb|EAQ10694.1| pyrazinamidase/nicotinamidase [Rhodobacterales bacterium HTCC2654]
Length = 203
Score = 265 bits (679), Expect = 1e-69, Method: Composition-based stats.
Identities = 68/213 (31%), Positives = 104/213 (48%), Gaps = 17/213 (7%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
LIV+D+QNDF P G+L V G+E++ I+ L++D V T+DWHP+ H SFA
Sbjct: 8 ALIVIDVQNDFC-PGGALAVDGGDEIVPGINRLIRDFPIR----VFTQDWHPAGHSSFAS 62
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
+H K P D +LWP HCV+ T G+ + +M I+ K
Sbjct: 63 SHPGKAPLEMV--------DMDYGPQVLWPDHCVQGTDGAAFHEDLMTDP---ADLILRK 111
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
GF + + YSAF + + T + YL + VG+A ++CV +A+ AA LG+
Sbjct: 112 GFRPEIDSYSAFFENDHRTSTGLEGYLRSRGATRLTFVGLATDFCVGWSAMDAARLGFAV 171
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINVVD 215
TV LD R I D ++ ++ ++
Sbjct: 172 TVRLDLCRAIDADG-SLDTALAGMRDAGATLIG 203
>ref|YP_001478953.1| Nicotinamidase [Serratia proteamaculans 568]
gb|ABV41825.1| Nicotinamidase [Serratia proteamaculans 568]
Length = 210
Score = 265 bits (677), Expect = 2e-69, Method: Composition-based stats.
Identities = 64/215 (29%), Positives = 108/215 (50%), Gaps = 14/215 (6%)
Query: 1 MK-TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHIS 59
MK L+++D+QNDF P G+L V G+ +I+ + + +V +DWHP+ H S
Sbjct: 1 MKTALLLIDLQNDFC-PGGALAVTNGDAVISVANQAIAACSARGEPVVACQDWHPANHRS 59
Query: 60 FAKNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKI 119
FA N G+ + WPVHCV+ + G++ Q+ + + I +
Sbjct: 60 FAVNAN---------APVGTLGELEGLPQVWWPVHCVQESQGAEFHPQLHQRDI---IAV 107
Query: 120 VDKGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELG 179
KG TD + YSAF D + T+++ +L+ + + I+G+A +YCVK + + A ELG
Sbjct: 108 FRKGQNTDIDSYSAFFDNGHRSHTELDSWLKTQNVSHLAIMGLATDYCVKFSVLDALELG 167
Query: 180 YKTTVLLDYTRPISDDPEVINKVKEELKAHNINVV 214
Y+TTV+ D R + P + ++ +V
Sbjct: 168 YRTTVITDGCRGVDLQPGDSQEALRIMQQAGAQLV 202
>ref|YP_001041928.1| Nicotinamidase [Rhodobacter sphaeroides ATCC 17029]
gb|ABN75156.1| Nicotinamidase [Rhodobacter sphaeroides ATCC 17029]
Length = 201
Score = 265 bits (677), Expect = 2e-69, Method: Composition-based stats.
Identities = 61/212 (28%), Positives = 102/212 (48%), Gaps = 18/212 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ LIV+D+QNDF P G+L V G+ +I I+ L+ + + T+DWHP+ H SFA
Sbjct: 6 EALIVIDVQNDFC-PGGALAVAGGDAIIPRINALLPEFGAR----IFTQDWHPADHSSFA 60
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
H+ P+S +LWP HCV+ T G++ + ++
Sbjct: 61 STHE-AVPFSLIEM--------PYGPQVLWPTHCVQGTRGAEFHPALETAP---ADLVLR 108
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + YSAF + T + YL + V + G+A ++CV +A+ AA LG++
Sbjct: 109 KGFRRGIDSYSAFFENDRTTPTGLEGYLRSRGIEAVTLAGLATDFCVAYSALDAARLGFR 168
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
TVL + I + + +K ++ + +
Sbjct: 169 VTVLEGASAAIDLNG-SLAAIKAQMAEAGVAL 199
>ref|ZP_01902192.1| pyrazinamidase/nicotinamidase [Roseobacter sp. AzwK-3b]
gb|EDM72608.1| pyrazinamidase/nicotinamidase [Roseobacter sp. AzwK-3b]
Length = 198
Score = 265 bits (677), Expect = 2e-69, Method: Composition-based stats.
Identities = 65/212 (30%), Positives = 106/212 (50%), Gaps = 17/212 (8%)
Query: 2 KTLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFA 61
+ LIV+DMQNDF P G+L VP G++++ I+ LM+ +++T+DWHP+ H SFA
Sbjct: 3 QALIVIDMQNDFC-PGGALAVPGGDDIVAGINALMEAFGA----VILTQDWHPAGHSSFA 57
Query: 62 KNHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVD 121
+H + P +LWP HCV+ + G+ + T+ I+
Sbjct: 58 SSHPGRAPMEMAEMA--------YGPQVLWPDHCVQGSAGAAFHAALDT---TRADLILR 106
Query: 122 KGFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYK 181
KGF + YSAF + T ++ YL++ E+ +VG+A ++CV +A+ AA LGY
Sbjct: 107 KGFRAAIDSYSAFFENDRRTPTGLHGYLQERGISELTLVGLATDFCVSYSALDAARLGYD 166
Query: 182 TTVLLDYTRPISDDPEVINKVKEELKAHNINV 213
V R I D + + +K + +
Sbjct: 167 VLVREGLCRAIDHDG-SLEAAVDAMKDAGVRI 197
>ref|YP_584002.1| isochorismatase hydrolase [Ralstonia metallidurans CH34]
gb|ABF08733.1| isochorismatase hydrolase [Ralstonia metallidurans CH34]
Length = 221
Score = 265 bits (677), Expect = 2e-69, Method: Composition-based stats.
Identities = 67/209 (32%), Positives = 108/209 (51%), Gaps = 17/209 (8%)
Query: 4 LIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAKN 63
L+V+D+QNDF+ P G+L VP+G+E++ I+ L + +V+T+DWHP+ H+SFA +
Sbjct: 9 LLVIDVQNDFM-PGGALAVPRGDEVVPIINRLAP----AFEHVVLTQDWHPAGHVSFATS 63
Query: 64 HKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDKG 123
H P+ T E +LWP HCV+ T G+ L + + ++ KG
Sbjct: 64 HVGTAPFQTMM--------LPYGEQVLWPDHCVQGTPGAALHADLR---IPHARMVIRKG 112
Query: 124 FLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKTT 183
+ + YSAF + KT + YL + V VG+A +YCV TA+ A G++
Sbjct: 113 HHANVDSYSAFMEADRATKTGLAGYLREQGVRRVVCVGLATDYCVAWTALDARAAGFEAV 172
Query: 184 VLLDYTRPISDDPEVINKVKEELKAHNIN 212
V+ D R I + +++ EL A +
Sbjct: 173 VVEDACRAIDLNG-SLDRAWRELAAAGVR 200
>ref|ZP_00825895.1| COG1335: Amidases related to nicotinamidase [Yersinia mollaretii
ATCC 43969]
Length = 216
Score = 265 bits (677), Expect = 2e-69, Method: Composition-based stats.
Identities = 64/211 (30%), Positives = 109/211 (51%), Gaps = 13/211 (6%)
Query: 3 TLIVVDMQNDFISPLGSLTVPKGEELINPISDLMQDADRDWHRIVVTRDWHPSRHISFAK 62
L+++D+QNDF P G+L V +G+ +I + + ++ ++DWHP+ H SFA
Sbjct: 4 ALLLIDLQNDFC-PGGALAVTEGDHVIAIANQAIDACLNQQIPVIASQDWHPAEHRSFAV 62
Query: 63 NHKDKEPYSTYTYHSPRPGDDSTQEGILWPVHCVKNTWGSQLVDQIMDQVVTKHIKIVDK 122
N G+ + + WPVHCV+N+ G+ Q+ + + K
Sbjct: 63 NSN---------AEPGTIGNLNGLPQVWWPVHCVQNSSGADWHPQLQQDAI---VTTFRK 110
Query: 123 GFLTDREYYSAFHDIWNFHKTDMNKYLEKHHTDEVYIVGVALEYCVKATAISAAELGYKT 182
G D + YSAF D KT ++ +L++H D ++I+G+A +YCVK + + A LGY+T
Sbjct: 111 GQDPDIDSYSAFFDNGRRAKTPLDDWLQQHGIDRLFIMGLATDYCVKYSVLDALALGYQT 170
Query: 183 TVLLDYTRPISDDPEVINKVKEELKAHNINV 213
TV+ D R ++ P+ + + +K NV
Sbjct: 171 TVISDGCRGVNLQPQDSLQALDAMKEAGANV 201
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.316 0.170 0.560
Lambda K H
0.267 0.0520 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,824,438,426
Number of Sequences: 6899187
Number of extensions: 193900798
Number of successful extensions: 564157
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 6466
Number of HSP's successfully gapped in prelim test: 824
Number of HSP's that attempted gapping in prelim test: 545417
Number of HSP's gapped (non-prelim): 9270
length of query: 216
length of database: 2,350,152,223
effective HSP length: 129
effective length of query: 87
effective length of database: 1,460,157,100
effective search space: 127033667700
effective search space used: 127033667700
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 77 (33.9 bits)