BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= YGL184C__[Saccharomyces_cerevisiae]
(465 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_011331.1| Cystathionine beta-lyase, converts cystath... 947 0.0
ref|XP_452961.1| unnamed protein product [Kluyveromyces lac... 565 e-159
ref|XP_449040.1| unnamed protein product [Candida glabrata]... 520 e-145
ref|NP_983345.1| ACL059Cp [Ashbya gossypii ATCC 10895] >gi|... 520 e-145
ref|XP_001536920.1| cystathionine beta-lyase [Ajellomyces c... 378 e-103
ref|XP_382108.1| hypothetical protein FG01932.1 [Gibberella... 378 e-103
ref|XP_001262409.1| cystathionine beta-lyase MetG [Neosarto... 377 e-102
ref|XP_001481546.1| cystathionine beta-lyase MetG [Aspergil... 376 e-102
ref|XP_001241519.1| hypothetical protein CIMG_08682 [Coccid... 373 e-101
ref|XP_001589290.1| hypothetical protein SS1G_09924 [Sclero... 372 e-101
ref|XP_001400722.1| hypothetical protein An14g00930 [Asperg... 372 e-101
ref|XP_001528683.1| cystathionine beta-lyase [Lodderomyces ... 371 e-101
gb|EDU44308.1| cystathionine beta-lyase [Pyrenophora tritic... 370 e-100
ref|XP_001558791.1| hypothetical protein BC1G_02862 [Botryo... 370 e-100
ref|XP_719662.1| cystathionine beta-lyase [Candida albicans... 367 1e-99
ref|XP_001223755.1| hypothetical protein CHGG_04541 [Chaeto... 366 2e-99
ref|XP_001825972.1| hypothetical protein [Aspergillus oryza... 366 3e-99
ref|XP_456620.1| hypothetical protein DEHA0A06897g [Debaryo... 365 4e-99
ref|XP_502248.1| hypothetical protein [Yarrowia lipolytica]... 365 5e-99
ref|XP_001486404.1| hypothetical protein PGUG_02075 [Pichia... 364 7e-99
ref|XP_367149.1| hypothetical protein MGG_07074 [Magnaporth... 364 7e-99
ref|XP_001274827.1| cystathionine beta-lyase MetG [Aspergil... 363 2e-98
gb|EEH38678.1| cystathionine beta-lyase [Paracoccidioides b... 363 2e-98
ref|XP_001382256.1| cystathionine beta-lyase [Pichia stipit... 363 2e-98
ref|XP_664655.1| hypothetical protein AN7051.2 [Aspergillus... 363 2e-98
ref|XP_001910364.1| unnamed protein product [Podospora anse... 363 2e-98
gb|ABM92783.1| putative cystathionine beta-lyase Met6p [Pic... 362 3e-98
gb|EEH45004.1| cystathionine beta-lyase [Paracoccidioides b... 360 2e-97
ref|XP_962657.1| cystathionine beta-lyase [Neurospora crass... 357 8e-97
ref|XP_001211424.1| cystathionine beta-lyase [Aspergillus t... 357 1e-96
gb|AAB03241.1| cystathionine beta-lyase [Emericella nidulans] 347 8e-94
ref|XP_761643.1| hypothetical protein UM05496.1 [Ustilago m... 339 2e-91
ref|XP_001836355.1| hypothetical protein CC1G_06440 [Coprin... 335 5e-90
ref|XP_567850.1| cystathionine beta-lyase [Cryptococcus neo... 325 5e-87
ref|XP_567851.1| cystathionine beta-lyase [Cryptococcus neo... 324 9e-87
ref|XP_001730996.1| hypothetical protein MGL_1995 [Malassez... 323 2e-86
ref|NP_588197.2| cystathionine beta-lyase (predicted) [Schi... 315 5e-84
ref|XP_001803788.1| hypothetical protein SNOG_13581 [Phaeos... 284 1e-74
emb|CAO63063.1| unnamed protein product [Vitis vinifera] 264 9e-69
gb|AAF74980.1|AF082890_1 cystathionine beta-lyase [Solanum ... 263 3e-68
emb|CAL55420.1| putative cystathionine beta-lyase precursor... 260 2e-67
ref|XP_001419577.1| cystathione beta lyase [Ostreococcus lu... 258 6e-67
ref|YP_591057.1| cystathionine beta-lyase [Acidobacteria ba... 253 2e-65
ref|NP_850712.1| CBL (CYSTATHIONINE BETA-LYASE) [Arabidopsi... 253 2e-65
ref|NP_191264.1| CBL (CYSTATHIONINE BETA-LYASE) [Arabidopsi... 252 6e-65
gb|ACO67451.1| cystathionine beta-lyase [Micromonas sp. RCC... 251 9e-65
gb|EEH58351.1| predicted protein [Micromonas pusilla CCMP1545] 249 3e-64
ref|XP_001699229.1| cystathionine beta-lyase [Chlamydomonas... 248 9e-64
ref|XP_001764951.1| predicted protein [Physcomitrella paten... 248 1e-63
dbj|BAA95830.1| putative cystathionine beta-lyase [Oryza sa... 244 1e-62
ref|NP_001056951.1| Os06g0175800 [Oryza sativa (japonica cu... 243 2e-62
ref|XP_001687646.1| cystathionine beta-lyase-like protein [... 243 2e-62
ref|XP_001464230.1| cystathionine beta-lyase-like protein [... 243 2e-62
gb|EAZ36012.1| hypothetical protein OsJ_019495 [Oryza sativ... 241 1e-61
ref|YP_383666.1| Cys/Met metabolism pyridoxal-phosphate-dep... 238 1e-60
ref|YP_002774266.1| cystathionine gamma-lyase [Brevibacillu... 237 2e-60
ref|YP_324649.1| Cys/Met metabolism pyridoxal-phosphate-dep... 236 3e-60
ref|YP_001487586.1| cystathionine beta-lyase [Bacillus pumi... 235 5e-60
ref|XP_001563339.1| cystathionine beta-lyase-like protein [... 234 1e-59
ref|NP_347031.1| Cystathionine beta-lyase [Clostridium acet... 233 2e-59
ref|YP_001037978.1| Cystathionine gamma-synthase [Clostridi... 233 3e-59
ref|ZP_03855854.1| cystathionine beta-lyase/cystathionine g... 229 3e-58
ref|ZP_02848090.1| Cystathionine gamma-synthase [Paenibacil... 229 5e-58
ref|ZP_01776902.1| Cystathionine gamma-synthase [Geobacter ... 226 3e-57
ref|YP_001126563.1| cystathionine beta-lyase [Geobacillus t... 225 5e-57
ref|YP_001307386.1| Cystathionine gamma-synthase [Clostridi... 225 7e-57
ref|YP_001680312.1| cystathionine beta-lyase [Heliobacteriu... 224 1e-56
ref|NP_980747.1| cystathionine beta-lyase [Bacillus cereus ... 223 2e-56
ref|ZP_02578916.1| cystathionine beta-lyase [Bacillus cereu... 223 2e-56
ref|ZP_02914409.1| Cystathionine gamma-synthase [Geobacillu... 223 3e-56
ref|YP_079997.1| cystathionine gamma-lyase YrhB [Bacillus l... 223 3e-56
ref|YP_148393.1| cystathionine beta-lyase [Geobacillus kaus... 223 4e-56
ref|YP_001232580.1| Cystathionine gamma-synthase [Geobacter... 223 4e-56
ref|YP_001376303.1| Cystathionine gamma-synthase [Bacillus ... 222 4e-56
ref|YP_752217.1| O-succinylhomoserine (thiol)-lyase [Shewan... 222 5e-56
ref|NP_834078.1| cystathionine beta-lyase [Bacillus cereus ... 222 5e-56
ref|YP_001759013.1| O-succinylhomoserine (thiol)-lyase [She... 222 6e-56
ref|ZP_02158428.1| cystathionine gamma-synthase [Shewanella... 221 7e-56
ref|YP_001647006.1| Cystathionine gamma-synthase [Bacillus ... 221 8e-56
ref|ZP_02254620.1| cystathionine beta-lyase [Bacillus cereu... 221 1e-55
ref|ZP_00741024.1| Cystathionine beta-lyase / Cystathionin... 221 1e-55
ref|YP_085695.1| cystathionine beta-lyase [Bacillus cereus ... 221 1e-55
ref|YP_038423.1| cystathionine beta-lyase [Bacillus thuring... 220 2e-55
ref|NP_347030.1| Cystathionine gamma-synthase [Clostridium ... 220 2e-55
ref|ZP_00237381.1| trans-sulfuration enzyme family protein ... 220 2e-55
ref|YP_001321485.1| Cystathionine gamma-synthase [Alkaliphi... 219 3e-55
ref|YP_001232581.1| Cystathionine gamma-synthase [Geobacter... 219 3e-55
ref|YP_901500.1| Cystathionine gamma-synthase [Pelobacter p... 219 5e-55
dbj|BAF80449.1| mimosinase [Leucaena leucocephala] 218 6e-55
ref|YP_001814810.1| Cystathionine gamma-synthase [Exiguobac... 218 8e-55
ref|NP_846819.1| cystathionine beta-lyase [Bacillus anthrac... 218 1e-54
ref|ZP_01853251.1| Cystathionine gamma-synthase [Planctomyc... 217 2e-54
ref|ZP_03913719.1| cystathionine gamma-lyase [Leuconostoc m... 217 2e-54
ref|YP_001039191.1| Cystathionine gamma-synthase [Clostridi... 217 2e-54
ref|YP_001680311.1| cystathionine gamma-synthase, putative ... 217 2e-54
ref|ZP_01859151.1| cystathionine beta-lyase [Bacillus sp. S... 216 3e-54
ref|ZP_02272396.1| Cystathionine gamma-synthase [Fusobacter... 216 3e-54
ref|YP_001092651.1| O-succinylhomoserine (thiol)-lyase [She... 216 3e-54
ref|YP_001500423.1| O-succinylhomoserine (thiol)-lyase [She... 216 3e-54
ref|YP_001475773.1| Cystathionine gamma-synthase [Shewanell... 216 3e-54
ref|YP_001558344.1| Cystathionine gamma-synthase [Clostridi... 216 4e-54
ref|ZP_01389889.1| Cystathionine gamma-synthase [Geobacter ... 216 5e-54
ref|YP_901501.1| Cystathionine gamma-synthase [Pelobacter p... 215 6e-54
ref|NP_266937.1| cystathionine gamma-synthase/cystathionine... 215 6e-54
ref|ZP_00394699.1| COG0626: Cystathionine beta-lyases/cysta... 215 7e-54
ref|NP_390603.1| cystathionine beta-lyase [Bacillus subtili... 215 7e-54
ref|NP_951999.1| cystathionine beta-lyase [Geobacter sulfur... 214 9e-54
ref|ZP_01173683.1| cystathionine beta-lyase [Bacillus sp. N... 214 1e-53
ref|YP_818758.1| Cystathionine beta-lyase/cystathionine gam... 214 1e-53
ref|ZP_01593967.1| Cystathionine gamma-synthase [Geobacter ... 214 1e-53
ref|YP_735562.1| O-succinylhomoserine (thiol)-lyase [Shewan... 213 2e-53
ref|ZP_02845106.1| Cystathionine gamma-synthase [Paenibacil... 213 2e-53
ref|NP_719586.1| cystathionine gamma-synthase [Shewanella o... 213 3e-53
gb|AAT40303.1| chloroplast cystathionine beta lyase [Medica... 213 4e-53
ref|ZP_03851922.1| cystathionine beta-lyase [Chryseobacteri... 212 4e-53
ref|ZP_01697151.1| Cys/Met metabolism pyridoxal-phosphate-d... 212 5e-53
ref|YP_964920.1| O-succinylhomoserine (thiol)-lyase [Shewan... 211 8e-53
ref|ZP_03955241.1| cystathionine gamma-lyase [Lactobacillus... 211 8e-53
ref|YP_175441.1| cystathionine gamma-synthase [Bacillus cla... 211 8e-53
ref|YP_001295285.1| Cys/Met metabolism PLP-dependent enzyme... 211 9e-53
ref|YP_871242.1| O-succinylhomoserine (thiol)-lyase [Shewan... 211 1e-52
ref|YP_001182146.1| O-succinylhomoserine (thiol)-lyase [She... 211 1e-52
ref|YP_001364767.1| O-succinylhomoserine (thiol)-lyase [She... 211 1e-52
ref|ZP_01704739.1| O-succinylhomoserine (thiol)-lyase [Shew... 211 1e-52
ref|ZP_01544503.1| cystathionine beta-lyase [Oenococcus oen... 211 1e-52
ref|ZP_01593966.1| Cystathionine gamma-synthase [Geobacter ... 211 1e-52
ref|YP_001672856.1| O-succinylhomoserine (thiol)-lyase [She... 211 1e-52
ref|ZP_01941014.1| cystathionine beta/gamma-lyase [Listeria... 210 2e-52
ref|YP_002773358.1| cystathionine beta-lyase [Brevibacillus... 210 2e-52
ref|ZP_01733647.1| cystathionine gamma-lyase [Flavobacteria... 210 2e-52
ref|YP_154611.1| Cystathionine gamma-synthase [Idiomarina l... 210 2e-52
ref|ZP_00234336.1| cystathionine beta/gamma-lyase [Listeria... 210 3e-52
ref|ZP_01841649.1| O-succinylhomoserine (thiol)-lyase [Shew... 209 3e-52
ref|XP_646022.1| cystathionine gamma-lyase [Dictyostelium d... 209 3e-52
ref|YP_001052118.1| O-succinylhomoserine (thiol)-lyase [She... 209 3e-52
ref|ZP_02522768.1| cystathionine beta-lyase [Bacillus cereu... 209 3e-52
ref|YP_001552998.1| O-succinylhomoserine (thiol)-lyase [She... 209 3e-52
ref|ZP_01930305.1| cystathionine beta/gamma-lyase [Listeria... 209 3e-52
ref|ZP_02061867.1| cystathionine gamma-lyase (Gamma-cystath... 209 3e-52
ref|ZP_00743270.1| Cystathionine beta-lyase [Bacillus thuri... 209 3e-52
ref|YP_001394392.1| MetB1 [Clostridium kluyveri DSM 555] >g... 209 3e-52
ref|ZP_02583477.1| cystathionine beta-lyase [Bacillus cereu... 209 3e-52
gb|ABL09516.1| cystathionine beta-lyase [Halobacillus halop... 209 4e-52
ref|YP_001193064.1| Cystathionine gamma-lyase [Flavobacteri... 209 4e-52
ref|XP_001678961.1| Hypothetical protein CBG24746 [Caenorha... 209 4e-52
ref|YP_001321486.1| Cystathionine gamma-synthase [Alkaliphi... 209 4e-52
ref|NP_465204.1| cystathionine beta-lyase [Listeria monocyt... 209 5e-52
ref|YP_810358.1| Cystathionine beta-lyase/cystathionine gam... 209 5e-52
ref|ZP_02309409.1| cystathionine beta-lyase [Listeria monoc... 209 5e-52
ref|ZP_02016714.1| Cystathionine gamma-synthase [Halorubrum... 208 7e-52
ref|YP_078488.1| putative Cystathionine beta-lyase [Bacillu... 208 7e-52
ref|ZP_01135652.1| cystathionine gamma-synthase, PLP-depend... 208 8e-52
ref|YP_300343.1| cystathionine gamma-synthase [Staphylococc... 208 8e-52
ref|YP_736572.1| O-succinylhomoserine (thiol)-lyase [Shewan... 208 8e-52
ref|ZP_01927597.1| cystathionine beta/gamma-lyase [Listeria... 208 8e-52
ref|NP_833968.1| cystathionine beta-lyase [Bacillus cereus ... 208 9e-52
ref|ZP_01041902.1| Cystathionine gamma-synthase [Idiomarina... 208 1e-51
ref|YP_808806.1| cystathionine gamma-synthase/cystathionine... 208 1e-51
ref|YP_348978.1| Cystathionine gamma-synthase [Pseudomonas ... 207 1e-51
ref|NP_471123.1| cystathionine beta-lyase [Listeria innocua... 207 1e-51
ref|YP_014299.1| cystathionine beta-lyase [Listeria monocyt... 207 1e-51
ref|YP_001405148.1| Cystathionine gamma-lyase [Candidatus M... 207 1e-51
ref|XP_001744338.1| predicted protein [Monosiga brevicollis... 207 1e-51
ref|ZP_03831504.1| cystathionine gamma-synthase [Pectobacte... 207 1e-51
ref|NP_867260.1| cystathionine gamma-lyase homolog [Rhodopi... 207 2e-51
ref|NP_643909.1| cystathionine gamma-lyase-like protein [Xa... 207 2e-51
ref|ZP_00231318.1| cystathionine beta/gamma-lyase [Listeria... 207 2e-51
ref|ZP_02185683.1| cystathionine beta-lyase [Carnobacterium... 207 2e-51
ref|XP_001445161.1| hypothetical protein GSPATT00013229001 ... 207 2e-51
ref|ZP_00238526.1| cystathionine beta-lyase [Bacillus cereu... 207 2e-51
ref|ZP_03807043.1| cystathionine beta-lyase [Lactobacillus ... 207 2e-51
gb|AAA64984.1| unknown [Pantoea agglomerans] 206 2e-51
ref|YP_001376208.1| Cystathionine gamma-synthase [Bacillus ... 206 3e-51
ref|XP_001607055.1| PREDICTED: similar to CG5345-PA [Nasoni... 206 3e-51
ref|ZP_02253340.1| cystathionine beta-lyase [Bacillus cereu... 206 3e-51
ref|YP_267213.1| cystathionine gamma-synthase [Colwellia ps... 206 4e-51
ref|YP_430828.1| Cystathionine gamma-synthase [Moorella the... 206 4e-51
ref|YP_849894.1| cystathionine beta-lyase [Listeria welshim... 206 4e-51
ref|YP_375448.1| Cystathionine gamma-synthase [Pelodictyon ... 206 5e-51
ref|NP_799144.1| cystathionine gamma-synthase [Vibrio parah... 205 5e-51
ref|ZP_01170376.1| cystathionine beta-lyase [Bacillus sp. N... 205 6e-51
ref|YP_001786093.1| cystathionine beta-lyase [Clostridium b... 205 6e-51
ref|YP_929043.1| Cystathionine gamma-synthase [Shewanella a... 205 7e-51
ref|ZP_01119325.1| Cystathionine gamma-synthase [Polaribact... 205 8e-51
ref|ZP_01958003.1| cystathionine gamma-synthase [Vibrio cho... 205 8e-51
ref|YP_001178741.1| cystathionine gamma-synthase [Enterobac... 205 8e-51
ref|ZP_01988130.1| O-succinylhomoserine (thiol)-lyase [Vibr... 205 8e-51
ref|NP_980630.1| cystathionine beta-lyase [Bacillus cereus ... 204 9e-51
ref|YP_001307385.1| Cystathionine gamma-synthase [Clostridi... 204 9e-51
ref|ZP_02137766.1| cystathionine gamma-synthase [Vibrio fis... 204 1e-50
ref|ZP_01389888.1| Cystathionine gamma-synthase [Geobacter ... 204 1e-50
ref|YP_199417.1| cystathionine gamma-lyase-like protein [Xa... 204 1e-50
ref|NP_495449.1| ZK1127.10 [Caenorhabditis elegans] >gi|170... 204 1e-50
ref|YP_001887506.1| cystathionine gamma-lyase [Clostridium ... 204 1e-50
gb|EEJ80271.1| cystathionine gamma-synthase [Kangiella kore... 204 1e-50
ref|XP_001014936.1| Cystathionine beta-lyase [Tetrahymena t... 204 1e-50
ref|NP_997769.2| cystathionase (cystathionine gamma-lyase) ... 204 1e-50
ref|ZP_02688088.1| cystathionine beta-lyase [Listeria monoc... 204 1e-50
ref|YP_591574.1| cystathionine gamma-lyase [Acidobacteria b... 204 1e-50
ref|ZP_03876613.1| cystathionine gamma-lyase [Haliangium oc... 204 1e-50
gb|AAH67624.1| Cth protein [Danio rerio] 204 2e-50
sp|P0C2T9|METC_LACLC Cystathionine beta-lyase (CBL) (Beta-c... 204 2e-50
ref|YP_630264.1| Cys/Met metabolism PLP-dependent enzyme [M... 204 2e-50
ref|ZP_01944126.1| cystathionine beta/gamma-lyase [Listeria... 204 2e-50
ref|YP_001307772.1| Cystathionine gamma-synthase [Clostridi... 204 2e-50
ref|ZP_02330637.1| cystathionine beta-lyase [Paenibacillus ... 204 2e-50
ref|ZP_04009503.1| cystathionine beta-lyase / cystathionine... 203 2e-50
ref|XP_001426097.1| hypothetical protein GSPATT00029327001 ... 203 2e-50
ref|ZP_02994313.1| hypothetical protein CLOSPO_01432 [Clost... 203 2e-50
ref|ZP_00590711.1| Cystathionine gamma-synthase [Pelodictyo... 203 3e-50
ref|YP_561628.1| O-succinylhomoserine (thiol)-lyase [Shewan... 203 3e-50
ref|ZP_03941301.1| cystathionine gamma-synthase [Lactobacil... 203 3e-50
ref|ZP_03938288.1| cystathionine gamma-synthase [Lactobacil... 203 3e-50
ref|YP_001390087.1| cystathionine beta-lyase [Clostridium b... 202 3e-50
ref|YP_038317.1| cystathionine beta-lyase [Bacillus thuring... 202 4e-50
ref|ZP_00724272.1| COG0626: Cystathionine beta-lyases/cysta... 202 4e-50
ref|ZP_02950046.1| cystathionine gamma-synthase [Clostridiu... 202 4e-50
ref|NP_846706.1| cystathionine beta-lyase [Bacillus anthrac... 202 4e-50
ref|YP_811264.1| Cystathionine beta-lyase/cystathionine gam... 202 4e-50
ref|ZP_03953509.1| cystathionine gamma-synthase [Lactobacil... 202 4e-50
ref|YP_001253267.1| cystathionine beta-lyase [Clostridium b... 202 4e-50
gb|EDN15995.1| cystathionine gamma-synthase [Vibrio cholera... 202 4e-50
ref|ZP_01949188.1| cystathionine gamma-synthase [Vibrio cho... 202 4e-50
ref|ZP_01695913.1| Cys/Met metabolism pyridoxal-phosphate-d... 202 5e-50
ref|YP_001708916.1| cystathionine gamma-synthase [Clavibact... 202 5e-50
ref|NP_927875.1| hypothetical protein plu0523 [Photorhabdus... 202 5e-50
ref|YP_001422026.1| YrhB [Bacillus amyloliquefaciens FZB42]... 202 5e-50
ref|YP_001512617.1| Cystathionine gamma-synthase [Alkaliphi... 202 5e-50
ref|NP_232311.1| cystathionine gamma-synthase [Vibrio chole... 202 5e-50
ref|NP_951998.1| cystathionine beta-lyase [Geobacter sulfur... 202 5e-50
ref|ZP_02904156.1| O-succinylhomoserine (thiol)-lyase [Esch... 202 7e-50
ref|ZP_03928912.1| cystathionine gamma-lyase [Acidaminococc... 201 7e-50
ref|NP_347566.1| Cystathionine gamma-synthase [Clostridium ... 201 8e-50
ref|NP_692030.1| cystathionine beta-lyase [Oceanobacillus i... 201 8e-50
ref|ZP_01982142.1| cystathionine gamma-synthase [Vibrio cho... 201 8e-50
ref|NP_611352.1| Eip55E CG5345-PA [Drosophila melanogaster]... 201 9e-50
ref|NP_931916.1| cystathionine gamma-synthase [Photorhabdus... 201 9e-50
ref|NP_784073.1| cystathionine beta-lyase [Lactobacillus pl... 201 9e-50
ref|ZP_01613151.1| cystathionine gamma-synthase, PLP-depend... 201 1e-49
ref|YP_001572513.1| hypothetical protein SARI_03556 [Salmon... 201 1e-49
ref|ZP_01093380.1| cystathionine gamma-lyase-like protein [... 201 1e-49
ref|ZP_03983763.1| cystathionine gamma-synthase/cystathioni... 201 1e-49
ref|YP_859527.1| cystathionine gamma-synthase [Escherichia ... 201 1e-49
ref|YP_001337879.1| cystathionine gamma-synthase [Klebsiell... 201 1e-49
ref|YP_002803098.1| cystathionine beta-lyase [Clostridium b... 201 1e-49
gb|ABG54361.1| cystathionine-gamma-synthase [Klebsiella pne... 201 1e-49
ref|YP_626847.1| cystathionine gamma-synthase/cystathionine... 201 1e-49
ref|YP_153019.1| cystathionine gamma-synthase [Salmonella e... 201 1e-49
ref|ZP_01486460.1| hypothetical protein VchoV5_02000923 [Vi... 201 1e-49
ref|YP_001454582.1| hypothetical protein CKO_03055 [Citroba... 201 1e-49
ref|YP_205650.1| cystathionine gamma-synthase, PLP-dependen... 201 1e-49
ref|ZP_02684964.1| hypothetical protein Salmentericaenteric... 201 1e-49
ref|ZP_02833544.1| hypothetical protein Salentericaenterica... 201 1e-49
ref|ZP_00709610.1| COG0626: Cystathionine beta-lyases/cysta... 201 1e-49
ref|YP_446463.1| Cys/Met metabolism PLP-dependent enzyme su... 201 2e-49
ref|YP_001465437.1| O-succinylhomoserine (thiol)-lyase [Esc... 200 2e-49
ref|YP_543467.1| cystathionine gamma-synthase [Escherichia ... 200 2e-49
ref|ZP_01776903.1| Cystathionine gamma-synthase [Geobacter ... 200 2e-49
ref|YP_312863.1| cystathionine gamma-synthase [Shigella son... 200 2e-49
ref|YP_002762679.1| cystathionine gamma-synthase [Gemmatimo... 200 2e-49
ref|NP_462981.1| cystathionine gamma-synthase [Salmonella t... 200 2e-49
ref|YP_001591205.1| hypothetical protein SPAB_05081 [Salmon... 200 2e-49
ref|YP_331099.1| cystathionine synthase/lyase (cystathionin... 200 2e-49
ref|ZP_02913262.1| Cystathionine gamma-synthase [Geobacillu... 200 2e-49
ref|ZP_00991531.1| cystathionine gamma-synthase [Vibrio spl... 200 2e-49
ref|ZP_01053161.1| Cystathionine gamma-synthase [Tenacibacu... 200 2e-49
gb|AAB86866.1| cystathionine gamma-lyase-like protein [Sten... 200 2e-49
ref|ZP_02196681.1| cystathionine gamma-synthase [Vibrio cam... 200 2e-49
ref|YP_001780368.1| cystathionine beta-lyase [Clostridium b... 200 2e-49
ref|YP_001646901.1| Cystathionine gamma-synthase [Bacillus ... 200 3e-49
ref|ZP_02963897.1| cystathionine gamma-synthase [Bifidobact... 200 3e-49
ref|ZP_01236677.1| cystathionine gamma-synthase [Vibrio ang... 200 3e-49
ref|YP_405211.1| cystathionine gamma-synthase [Shigella dys... 199 3e-49
ref|ZP_00972545.1| COG0626: Cystathionine beta-lyases/cysta... 199 3e-49
ref|ZP_02345156.1| hypothetical protein Sentente_13009 [Sal... 199 3e-49
ref|ZP_00820472.1| COG0626: Cystathionine beta-lyases/cysta... 199 3e-49
gb|EEH96230.1| cystathionine gamma-synthase [Citrobacter sp... 199 3e-49
ref|ZP_01161623.1| cystathionine gamma-synthase [Photobacte... 199 3e-49
ref|ZP_02565422.1| hypothetical protein Senten_06410 [Salmo... 199 3e-49
ref|NP_206906.1| cystathionine gamma-synthase/cystathionine... 199 4e-49
ref|ZP_04015432.1| cystathionine beta-lyase [Lactobacillus ... 199 4e-49
ref|XP_001750526.1| predicted protein [Monosiga brevicollis... 199 4e-49
ref|NP_418374.1| cystathionine gamma-synthase, PLP-dependen... 199 4e-49
ref|ZP_02652432.1| cystathionine gamma-synthase [Salmonella... 199 4e-49
ref|ZP_04003124.1| cystathionine gamma-synthase [Escherichi... 199 4e-49
ref|NP_457953.1| cystathionine gamma-synthase [Salmonella e... 199 4e-49
ref|ZP_01474132.1| hypothetical protein VEx2w_02003301 [Vib... 199 4e-49
ref|ZP_02562207.1| hypothetical protein Sente_18449 [Salmon... 199 4e-49
ref|YP_001843789.1| cystathionine beta-lyase [Lactobacillus... 199 4e-49
ref|ZP_02618072.1| cystathionine beta-lyase [Clostridium bo... 199 5e-49
ref|ZP_00924852.1| COG0626: Cystathionine beta-lyases/cysta... 199 5e-49
ref|YP_410238.1| cystathionine gamma-synthase [Shigella boy... 199 5e-49
ref|NP_389070.1| cystathionine beta-lyase [Bacillus subtili... 199 5e-49
ref|NP_814082.1| cystathionine gamma-synthase/cystathionine... 199 5e-49
gb|ACO15591.1| Cystathionine gamma-lyase [Caligus clemensi] 199 6e-49
ref|YP_576031.1| O-succinylhomoserine (thiol)-lyase [Nitrob... 199 6e-49
ref|ZP_01261729.1| cystathionine gamma-synthase [Vibrio alg... 199 6e-49
ref|ZP_03838999.1| cystathionine gamma-synthase [Citrobacte... 199 6e-49
ref|NP_756746.1| cystathionine gamma-synthase [Escherichia ... 198 7e-49
gb|AAD17839.1| ecdysteroid-inducible polypeptide EIP40 [Dro... 198 7e-49
>ref|NP_011331.1| Cystathionine beta-lyase, converts cystathionine into homocysteine;
Str3p [Saccharomyces cerevisiae]
sp|P53101|STR3_YEAST Cystathionine beta-lyase (CBL) (Beta-cystathionase) (Cysteine
lyase)
emb|CAA62790.1| putative cystathionine /cysteine metabolism protein [Saccharomyces
cerevisiae]
emb|CAA96896.1| unnamed protein product [Saccharomyces cerevisiae]
gb|EDN61942.1| cystathionine beta-lyase [Saccharomyces cerevisiae YJM789]
Length = 465
Score = 947 bits (2447), Expect = 0.0, Method: Composition-based stats.
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MPIKRLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
MPIKRLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH
Sbjct: 1 MPIKRLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF
Sbjct: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD
Sbjct: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
Query: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV
Sbjct: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
Query: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF
Sbjct: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
Query: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
VGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM
Sbjct: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLF 420
PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLF
Sbjct: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLF 420
Query: 421 NKLNKNLAVNTTIDDLHKPLSIYEEFYNQDLIRKDSELNIKSSKL 465
NKLNKNLAVNTTIDDLHKPLSIYEEFYNQDLIRKDSELNIKSSKL
Sbjct: 421 NKLNKNLAVNTTIDDLHKPLSIYEEFYNQDLIRKDSELNIKSSKL 465
>ref|XP_452961.1| unnamed protein product [Kluyveromyces lactis]
emb|CAH01812.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
Length = 460
Score = 565 bits (1456), Expect = e-159, Method: Composition-based stats.
Identities = 286/464 (61%), Positives = 354/464 (76%), Gaps = 13/464 (2%)
Query: 1 MPIKRLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
M L+T +V+ S ND++ +SVPP+Y STTFK + + Q YDY+RSGNPTR+VLQ
Sbjct: 1 MSKPSLNTSLVSV-SHNDKYGSSVPPLYQSTTFKAS-SFDQLQEYDYTRSGNPTRTVLQQ 58
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
QI LY V E V AVSSGMTALD+ILR L+ +H PTIIAGDDLYGGTQRLL F
Sbjct: 59 QIANLYDVAPEQVFAVSSGMTALDIILRTLI---DNSDHIPTIIAGDDLYGGTQRLLTFL 115
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVK---CI 177
+ ++HA +H DT+D E F ++ SL +VD VLLESPTNPL KV D+PR+ +FVK
Sbjct: 116 QTRNHAKVIHTDTTDAESFIKLYNSLGQVDIVLLESPTNPLMKVADLPRLCQFVKQKGGS 175
Query: 178 SPDTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKL 237
S + +VVDNTMMSGLN NPLQ G DVVYES TKYLNGHHD+M GVII+K ++A +
Sbjct: 176 SSNCKIVVDNTMMSGLNSNPLQF--GADVVYESGTKYLNGHHDIMAGVIIAKK-DVAPSV 232
Query: 238 YFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATK 297
YFVINSTGAGLSPMDSWLL+RGLKTL VRLY+QQ NAM+L+HWL++ CGFKPT N+ K
Sbjct: 233 YFVINSTGAGLSPMDSWLLIRGLKTLSVRLYKQQINAMVLSHWLQDICGFKPTDNNQQLK 292
Query: 298 TRFVGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSL 357
TRFVGL S+P F+LHKSFNNGPGAVLS ETG S+ +V+SK+L+IWAVTVSFGCVNSL
Sbjct: 293 TRFVGLESHPQFELHKSFNNGPGAVLSIETGDLALSEAIVTSKRLNIWAVTVSFGCVNSL 352
Query: 358 LSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGK 417
+SMPCKMSHASIDPELRK+R FPEDL+RLCCGIE++ DL+ DLLAA +A +IE+++ G
Sbjct: 353 ISMPCKMSHASIDPELRKQRAFPEDLIRLCCGIEDVKDLQYDLLAAFEEAGLIELQQRGN 412
Query: 418 --YLFNKLNKNLAVNTTIDDLHKPLSIYEEFYNQDLIRKDSELN 459
YL NK N ++A N + + ++Y++F+ Q L+ K S L+
Sbjct: 413 DTYLLNKKNGHIARNNIGETYQENYNVYDQFFGQRLVSKTSHLH 456
>ref|XP_449040.1| unnamed protein product [Candida glabrata]
emb|CAG62010.1| unnamed protein product [Candida glabrata CBS 138]
Length = 450
Score = 520 bits (1339), Expect = e-145, Method: Composition-based stats.
Identities = 267/459 (58%), Positives = 344/459 (74%), Gaps = 20/459 (4%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQEN-VLA 75
+ + ASV P+YLSTTFKVDL NE+ Q YDYSRSGNPTR++LQ Q+ KLY N V A
Sbjct: 2 SQHYGASVAPLYLSTTFKVDLENENNQ-YDYSRSGNPTRTLLQQQVAKLYDDIDPNFVFA 60
Query: 76 VSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSD 135
VSSGMTALDV+LR L + T+NH IIAGDDLYGGTQRLLN K ++H D S
Sbjct: 61 VSSGMTALDVVLRSF-LPSETNNHC--IIAGDDLYGGTQRLLNLLKISID--TMHFDLSH 115
Query: 136 FEKFKTVFQSL-----DKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMM 190
E FK F L VD ++LESPTNPLCK++DIP +++F++ SP+T +V+DNTMM
Sbjct: 116 TENFKAKFYDLVTIKKTIVDIIVLESPTNPLCKIIDIPHLIKFIRKYSPETLIVIDNTMM 175
Query: 191 SGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSP 250
SGLNCNPL+ G DVVYESATKYLNGHHD+M GVII+K +A K+YF+INSTG+GL+P
Sbjct: 176 SGLNCNPLKF--GADVVYESATKYLNGHHDIMAGVIIAKNKLLAEKIYFLINSTGSGLNP 233
Query: 251 MDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFK 310
MDSWLL+RGLKTL +RL++QQ NA+ ++HWLE CGFK N KTR++GL+S+PD++
Sbjct: 234 MDSWLLIRGLKTLSIRLHKQQLNALAISHWLEEGCGFKTHNNNNNLKTRYIGLKSHPDYE 293
Query: 311 LHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASID 370
LH+SFN GPGAV+S +TGS SK++V+SK L +W VTVSFGCVNSL+SMPC MSHASID
Sbjct: 294 LHRSFNKGPGAVISLQTGSIPISKKIVASKLLKLWNVTVSFGCVNSLISMPCLMSHASID 353
Query: 371 PELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENG--KYLFNKLNKNLA 428
PELRKER FPEDL+RLCCGIE++ L++DLL A V+A +I ++++ YL N LN ++
Sbjct: 354 PELRKERQFPEDLIRLCCGIEDVKALQEDLLGAFVEAGVITIKKHDGRTYLINNLNGHIG 413
Query: 429 VNTTIDDL-HKPLSIYEEFYN-QDLIRKDSELNIKSSKL 465
+ +L HK ++Y++F++ Q+ I K+ + SKL
Sbjct: 414 EHFIYSELEHK--NVYDQFFSYQNYIEKNLLAKQRLSKL 450
>ref|NP_983345.1| ACL059Cp [Ashbya gossypii ATCC 10895]
gb|AAS51169.1| ACL059Cp [Ashbya gossypii ATCC 10895]
Length = 453
Score = 520 bits (1339), Expect = e-145, Method: Composition-based stats.
Identities = 256/441 (58%), Positives = 320/441 (72%), Gaps = 11/441 (2%)
Query: 7 DTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLY 66
++ +V G DQH ASVP +Y STTFK D Q YDY+RSGNPTR+V + Q+G+LY
Sbjct: 7 ESRLVCVGEHGDQHGASVPALYQSTTFK--QRTLDGQAYDYTRSGNPTRTVAEGQVGRLY 64
Query: 67 RVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHA 126
V E V+AV+SGMTALDV+LR ++ G T+IAGDDLYGGTQRLL + A
Sbjct: 65 GVGPEQVMAVASGMTALDVVLRAVLRRGGRG----TVIAGDDLYGGTQRLLGLLAETGQA 120
Query: 127 VSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVD 186
VHVDT+D F + +V CVLLESPTNPL KV D+P ++ VK +P VVVD
Sbjct: 121 RVVHVDTADTAAFCAAVAAAGEVACVLLESPTNPLMKVADVPALVAHVKAHAPGCRVVVD 180
Query: 187 NTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGA 246
NTMMSGLNCNPL+L G D VYESATKYLNGHHD+M GVI++ T +A + YFV+NS GA
Sbjct: 181 NTMMSGLNCNPLRL--GADYVYESATKYLNGHHDIMAGVIVAATRALAEEAYFVVNSVGA 238
Query: 247 GLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSN 306
GL+PMD+WLL+RGLKTL +RLY+QQ NAM+LAHWL CGF+ N A +TRFVGLRS+
Sbjct: 239 GLAPMDAWLLIRGLKTLSLRLYKQQHNAMVLAHWLREVCGFRAVGGNHALQTRFVGLRSH 298
Query: 307 PDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSH 366
P KLH+SFN GPGAVLS +TG S+R+V SKKL W VTVSFGCVNSL+SMPC+MSH
Sbjct: 299 PQHKLHRSFNRGPGAVLSIQTGDTALSERIVCSKKLQFWGVTVSFGCVNSLISMPCRMSH 358
Query: 367 ASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLFNKLNKN 426
ASIDPELRK R FPEDL+RL CG+E++ DL++DLLAA+ DA + VR+ G+ + N+LN +
Sbjct: 359 ASIDPELRKARQFPEDLIRLSCGVEDVEDLQQDLLAALEDAGAVVVRDGGRTIVNRLNGH 418
Query: 427 LAVNTTIDDLHKPLSIYEEFY 447
+ + + + IY +F+
Sbjct: 419 IGTHVSSSEQR---CIYRDFF 436
>ref|XP_001536920.1| cystathionine beta-lyase [Ajellomyces capsulatus NAm1]
gb|EDN04363.1| cystathionine beta-lyase [Ajellomyces capsulatus NAm1]
Length = 447
Score = 378 bits (971), Expect = e-103, Method: Composition-based stats.
Identities = 205/396 (51%), Positives = 261/396 (65%), Gaps = 26/396 (6%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
NDQ +AS P+Y S TFK N + YDY+RSGNPTR+ L+ + K+ + + L V
Sbjct: 63 NDQFNASSVPIYQSATFKQTSGNGGGE-YDYTRSGNPTRTHLERHLAKI--MSAQRALVV 119
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
SSGM ALDVI R LL D ++ GDDLYGGT RLL + + HVDT+
Sbjct: 120 SSGMAALDVITR---LLKPGDE----VVTGDDLYGGTHRLLKYLATHGGIIVHHVDTTRP 172
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
EK V ++ ++ VLLE+PTNPL K+VDIP+I +P+ V VDNTM+S L N
Sbjct: 173 EKVSEVLGAMTRL--VLLETPTNPLIKIVDIPQIASLTHEANPNALVAVDNTMLSPLLLN 230
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
PL L G D+VYES TKYL+GHHDLM GV+ + KLYF INS+G GLSP DSWLL
Sbjct: 231 PLDL--GADIVYESGTKYLSGHHDLMAGVVAVNDLSLGEKLYFTINSSGCGLSPFDSWLL 288
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
+RG+KTL VR+ QQQ NA +A +LEN GF + R+ GL+S+P + LH+S
Sbjct: 289 LRGVKTLKVRMEQQQSNAQRIAEFLENH-GF---------RVRYPGLKSHPQYDLHRSMA 338
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
GPGAVLSFETG S+R+V S KL WA++VSFGCVNSL+S+PC+MSHASID + R++
Sbjct: 339 RGPGAVLSFETGDVTTSERIVESAKL--WAISVSFGCVNSLISLPCRMSHASIDAKTRRD 396
Query: 377 RDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEV 412
RD PEDL+RLC GIE++ DL DL A+V A + V
Sbjct: 397 RDMPEDLIRLCVGIEDVDDLIDDLRRALVQAGAVTV 432
>ref|XP_382108.1| hypothetical protein FG01932.1 [Gibberella zeae PH-1]
Length = 436
Score = 378 bits (970), Expect = e-103, Method: Composition-based stats.
Identities = 209/411 (50%), Positives = 267/411 (64%), Gaps = 26/411 (6%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
L T +V T S+ DQ+ AS P+Y S TFK + Q YDY+RSGNPTR+ L+ I K+
Sbjct: 34 LATELVYTDSK-DQYGASSVPIYQSATFKQTSASGGQQEYDYTRSGNPTRTHLERHIAKI 92
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
+ LA+SSGM ALDVI R LL D +I GDDLYGG+ RLL +
Sbjct: 93 MNA--QRALAISSGMGALDVITR---LLRPGDE----VITGDDLYGGSHRLLTYLAANQG 143
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
V HVDT+ + + +K VLLE+PTNPL KVVDIP I R V ++P VVV
Sbjct: 144 IVVHHVDTTTVDSVRARLS--EKTAMVLLETPTNPLIKVVDIPSIARLVHDVNPKALVVV 201
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DNTM+S + NPL + GCD+VYES TKYL+GHHD+M GVI +I KL+FVINSTG
Sbjct: 202 DNTMLSPMLFNPLDV--GCDIVYESGTKYLSGHHDIMAGVIAVNDSQIGDKLFFVINSTG 259
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
GLSP DS+LL+RG+KTL +R+ +QQ NA +A +LE S GF + R+ GL+S
Sbjct: 260 CGLSPNDSFLLMRGVKTLAIRMEKQQANAQAIAEFLE-SRGF---------RVRYPGLKS 309
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P + LH S G GAVLSFETG S+R+V + +L WA++VSFGCVNSL+SMPC+MS
Sbjct: 310 HPQYDLHWSMARGAGAVLSFETGDPAVSERIVEAARL--WAISVSFGCVNSLISMPCQMS 367
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENG 416
HASID + R ER PED++RLC GIE+ DL +DL A+V A + V +G
Sbjct: 368 HASIDAKTRAERQMPEDIIRLCVGIEDPTDLIEDLSRALVQAGAVTVTMDG 418
>ref|XP_001262409.1| cystathionine beta-lyase MetG [Neosartorya fischeri NRRL 181]
gb|EAW20512.1| cystathionine beta-lyase MetG [Neosartorya fischeri NRRL 181]
Length = 443
Score = 377 bits (968), Expect = e-102, Method: Composition-based stats.
Identities = 212/409 (51%), Positives = 265/409 (64%), Gaps = 27/409 (6%)
Query: 8 TVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYR 67
T +V T S NDQ++AS P+Y S TFK + YDY+RSGNPTR+ L+ + K+
Sbjct: 50 TELVYTDS-NDQYNASSVPIYQSATFK-QTSGGGGGEYDYTRSGNPTRTHLERHLAKI-- 105
Query: 68 VPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAV 127
+ + L VSSGM ALDVI R LL D ++ GDDLYGGT RLL + +
Sbjct: 106 MSAQRALVVSSGMAALDVISR---LLRPGDE----VVTGDDLYGGTHRLLKYLSTNGGII 158
Query: 128 SVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDN 187
HVDT+ EK + V K VLLE+PTNPL K+VDIP+I I+P V VDN
Sbjct: 159 VHHVDTTQPEKVREVLTP--KTAMVLLETPTNPLIKIVDIPQIATAAHEINPSCLVAVDN 216
Query: 188 TMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAG 247
TMMS L NPL+L G D+VYES TKYL+GHHDLM GVI + +LYF IN++G G
Sbjct: 217 TMMSPLLLNPLEL--GADIVYESGTKYLSGHHDLMAGVIAVNDLALGERLYFPINASGCG 274
Query: 248 LSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNP 307
LSP DSWLL+RG+KTL VR+ QQQ NA +A +LE S GF K R+ GLRS+P
Sbjct: 275 LSPFDSWLLMRGVKTLKVRMDQQQSNAQRIAEFLE-SHGF---------KVRYPGLRSHP 324
Query: 308 DFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHA 367
++LH S G GAVLSFETG S+R+V S KL WA++VSFGCVNSL+SMPC+MSHA
Sbjct: 325 QYELHHSMARGAGAVLSFETGDVGVSERIVESAKL--WAISVSFGCVNSLISMPCRMSHA 382
Query: 368 SIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENG 416
SID + R+ER PEDL+RLC GIE++ DL DL A+V A + + +G
Sbjct: 383 SIDAKTRQERAMPEDLIRLCVGIEDVDDLIDDLRRALVQAGAVNITLDG 431
>ref|XP_001481546.1| cystathionine beta-lyase MetG [Aspergillus fumigatus Af293]
gb|EBA27192.1| cystathionine beta-lyase MetG [Aspergillus fumigatus Af293]
gb|EDP47305.1| cystathionine beta-lyase MetG [Aspergillus fumigatus A1163]
Length = 443
Score = 376 bits (965), Expect = e-102, Method: Composition-based stats.
Identities = 210/409 (51%), Positives = 265/409 (64%), Gaps = 27/409 (6%)
Query: 8 TVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYR 67
T +V T S NDQ++AS P+Y S TFK + YDY+RSGNPTR+ L+ + K+
Sbjct: 50 TELVYTDS-NDQYNASSVPIYQSATFK-QTSGGGGGEYDYTRSGNPTRTHLERHLAKI-- 105
Query: 68 VPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAV 127
+ + L VSSGM ALDVI R LL D ++ GDDLYGGT RLL + +
Sbjct: 106 MSAQRALVVSSGMAALDVISR---LLRPGDE----VVTGDDLYGGTHRLLKYLSTNGGII 158
Query: 128 SVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDN 187
HVDT+ EK + V K VLLE+PTNPL K+VDIP+I ++P V VDN
Sbjct: 159 VHHVDTTQPEKVREVLTP--KTAMVLLETPTNPLIKIVDIPQIATAAHEVNPSCLVAVDN 216
Query: 188 TMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAG 247
TMMS L NPL+L G D+VYES TKYL+GHHDLM GVI + +LYF IN++G G
Sbjct: 217 TMMSPLLLNPLEL--GADIVYESGTKYLSGHHDLMAGVIAVNDLALGERLYFPINASGCG 274
Query: 248 LSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNP 307
LSP DSWLL+RG+KTL VR+ QQQ NA +A +LE + GF K R+ GLRS+P
Sbjct: 275 LSPFDSWLLMRGVKTLKVRMDQQQSNAQRIAEFLE-AHGF---------KVRYPGLRSHP 324
Query: 308 DFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHA 367
++LH S G GAVLSFETG S+R+V S KL WA++VSFGCVNSL+SMPC+MSHA
Sbjct: 325 QYELHHSMARGAGAVLSFETGDVAVSERIVESAKL--WAISVSFGCVNSLISMPCRMSHA 382
Query: 368 SIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENG 416
SID + R+ER PEDL+RLC GIE++ DL DL A+V A + + +G
Sbjct: 383 SIDAKTRQERAMPEDLIRLCVGIEDVDDLIDDLRRALVQAGAVNITLDG 431
>ref|XP_001241519.1| hypothetical protein CIMG_08682 [Coccidioides immitis RS]
gb|EAS29936.1| hypothetical protein CIMG_08682 [Coccidioides immitis RS]
Length = 458
Score = 373 bits (957), Expect = e-101, Method: Composition-based stats.
Identities = 208/409 (50%), Positives = 260/409 (63%), Gaps = 29/409 (7%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
NDQ+ AS P+Y S TFK + + YDY+RSGNPTR+ L+ + K+ + + L V
Sbjct: 64 NDQYKASSMPIYQSATFKQNSGGGGGE-YDYTRSGNPTRTHLERHLAKI--MSAQRALVV 120
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
SSGM ALDVI R LL D +I GDDLYGGT RLL + + HVDT+
Sbjct: 121 SSGMAALDVITR---LLKPGDE----VITGDDLYGGTHRLLKYLSTHGGIIVHHVDTTTP 173
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
EK V VLLE+PTNPL K+VDI RI +P+ V VDNTM+S L N
Sbjct: 174 EKVGEVLGP--NTAMVLLETPTNPLIKIVDIARIATMTHEANPNALVAVDNTMLSPLLLN 231
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
PL L G D+VYES TKYL+GHHDLM GVI + KLYF IN++G GLSP DSWLL
Sbjct: 232 PLDL--GADIVYESGTKYLSGHHDLMAGVIAVNNLSLGEKLYFPINASGCGLSPFDSWLL 289
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
+RG+KTL VR+ QQQ NA +A +LE S GF + R+ GL+S+P + LH+S
Sbjct: 290 LRGVKTLKVRMEQQQSNAQQIAEFLE-SHGF---------RVRYPGLKSHPQYDLHRSMA 339
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
G GAVLSFETG S+R+V S KL WA++VSFGCVNSL+SMPC+MSHASID + R+E
Sbjct: 340 RGAGAVLSFETGDVAMSERIVESAKL--WAISVSFGCVNSLISMPCRMSHASIDAKTRQE 397
Query: 377 RDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLFNKLNK 425
R PEDL+RLC GIE++ DL DL A+V A + V +G F +N+
Sbjct: 398 RAMPEDLIRLCVGIEDVDDLIDDLRRALVQAGAVSVTVDG---FQSVNQ 443
>ref|XP_001589290.1| hypothetical protein SS1G_09924 [Sclerotinia sclerotiorum 1980]
gb|EDN94056.1| hypothetical protein SS1G_09924 [Sclerotinia sclerotiorum 1980]
Length = 459
Score = 372 bits (954), Expect = e-101, Method: Composition-based stats.
Identities = 213/439 (48%), Positives = 278/439 (63%), Gaps = 34/439 (7%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
L T +V T ++ DQ+ AS P+Y S TFK +L ++ YDY+RSGNPTR+ L+ + K+
Sbjct: 51 LATELVYTETK-DQYGASSMPIYQSATFKQNLAGGGSE-YDYTRSGNPTRTHLERHLAKI 108
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
+ L V SGM ALDVI R +L G + +I GDDLYGGT RLL + +
Sbjct: 109 MNATR--ALVVGSGMGALDVITR--ILRPGDE-----VITGDDLYGGTNRLLTYLAANTG 159
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
V HVDT++ +K K V K VLLE+PTNPL K+VDI I R ++ VVV
Sbjct: 160 IVVHHVDTTNPDKVKAVLGP--KTAMVLLETPTNPLIKIVDIATIARTAHELNEKALVVV 217
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DNTM+S + CNPL L G D+VYES TKYL+GHHD+M GV+ P I K+YF INSTG
Sbjct: 218 DNTMLSPMLCNPLDL--GADIVYESGTKYLSGHHDIMAGVLAFNDPTIGDKMYFTINSTG 275
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
GLSP DS+LL+RG+KTL +R+ +QQ NA +A +LE S GF + R+ GL+S
Sbjct: 276 CGLSPNDSFLLMRGIKTLAIRMERQQTNAQAIAEFLE-SHGF---------RVRYPGLKS 325
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P + LH S G GAVLSFETG S+R+V + KL W ++VSFGCVNSL+SMPC+MS
Sbjct: 326 HPQYDLHWSMARGAGAVLSFETGDVALSERIVEAAKL--WGISVSFGCVNSLISMPCQMS 383
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLFNKLNK 425
HASID + RKER PED++RLC GIE++ DL DL A+V A ++V +G F+ +
Sbjct: 384 HASIDAKTRKERQMPEDIIRLCVGIEDVTDLIDDLSRALVQAGAVKVTLDG---FHAVGA 440
Query: 426 NLAVN----TTIDDLHKPL 440
A+ T DD PL
Sbjct: 441 AQAIAEIPITESDDAAAPL 459
>ref|XP_001400722.1| hypothetical protein An14g00930 [Aspergillus niger]
emb|CAK41892.1| unnamed protein product [Aspergillus niger]
Length = 433
Score = 372 bits (954), Expect = e-101, Method: Composition-based stats.
Identities = 207/396 (52%), Positives = 257/396 (64%), Gaps = 26/396 (6%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
NDQ++AS P+Y S TFK + YDY+RSGNPTR+ L+ + K+ + + L V
Sbjct: 53 NDQYNASSVPIYQSATFK-QTSGGGGGEYDYTRSGNPTRTHLERHLAKI--MSAQRALVV 109
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
SSGM ALDVI R LL D ++ GDDLYGGT RLL + + HVDT+
Sbjct: 110 SSGMAALDVISR---LLRPGDE----VVTGDDLYGGTNRLLKYLSTNGGIIVHHVDTTVP 162
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
EK + V S K VLLE+PTNPL KVVDIP+I +P+ V VDNTMMS L N
Sbjct: 163 EKVREVLTS--KTAMVLLETPTNPLIKVVDIPQIAAAAHEANPNCVVSVDNTMMSPLLLN 220
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
PL+L G D+VYES TKYL+GHHDLM GV+ + +LYF IN++G GLSP DSWLL
Sbjct: 221 PLEL--GADIVYESGTKYLSGHHDLMAGVLAVNDLSLGERLYFTINASGCGLSPFDSWLL 278
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
+RG+KTL VR+ QQQ NA +A +LE GF K R+ GLRS+P ++LH S
Sbjct: 279 LRGVKTLKVRMDQQQSNAQRIAEFLETH-GF---------KVRYPGLRSHPQYELHHSMA 328
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
G GAVLSFETG S+R+V S KL WA++VSFGCVNSL+SMPC+MSHASID + R+E
Sbjct: 329 RGSGAVLSFETGDVGVSERIVESAKL--WAISVSFGCVNSLISMPCRMSHASIDEKTRRE 386
Query: 377 RDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEV 412
R PEDL+RLC GIE+ DL DL A+V A + V
Sbjct: 387 RAMPEDLIRLCVGIEDADDLIDDLRRALVQAGAVNV 422
>ref|XP_001528683.1| cystathionine beta-lyase [Lodderomyces elongisporus NRRL YB-4239]
gb|EDK43025.1| cystathionine beta-lyase [Lodderomyces elongisporus NRRL YB-4239]
Length = 407
Score = 371 bits (952), Expect = e-101, Method: Composition-based stats.
Identities = 210/420 (50%), Positives = 282/420 (67%), Gaps = 30/420 (7%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKV-DLNNEDAQNYDYSRSGNPTRSVLQHQIGK 64
L+T +V + S DQ++ASVPP+Y S TFK L+N A YDY+RSGNPTR+ LQ + K
Sbjct: 12 LETELVLSKS-GDQYNASVPPLYQSATFKQPSLSNMGA--YDYTRSGNPTRTHLQTHLAK 68
Query: 65 LYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQS 124
+ + ++ AVSSGM LDVI R LL D +IAGDDLYGGT RLL + ++
Sbjct: 69 IMKA--KHAFAVSSGMGCLDVITR---LLKPGDE----VIAGDDLYGGTHRLLTYLNKKG 119
Query: 125 HAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVV 184
++ H DT++ E K + +K + LESPTNPL KVVD+ I + ++PD VV
Sbjct: 120 DLIAHHYDTTNTELIK--LKITEKTRMIFLESPTNPLIKVVDVKSIADYGHLVNPDLIVV 177
Query: 185 VDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINST 244
DNTMMS + PL L G D+ YESATKYLNGHHD+M GVI +++ ++ +LY+VINST
Sbjct: 178 FDNTMMSPIFMTPLDL--GVDIQYESATKYLNGHHDIMAGVIATRSTPLSEQLYYVINST 235
Query: 245 GAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLR 304
G GLSP D WLL RGLKTL VR+ +QQ N + +A +LEN GF K R+ GL+
Sbjct: 236 GCGLSPFDCWLLSRGLKTLAVRIERQQDNCIKIAKFLEN-IGF---------KVRYPGLK 285
Query: 305 SNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKM 364
S+P ++LH S +G GAVLSFETGS + S+++V + I+ + VSFGCVNSL+SMPC+M
Sbjct: 286 SHPQYELHASMCSGFGAVLSFETGSIKLSEKIVENT--DIFGIAVSFGCVNSLISMPCRM 343
Query: 365 SHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLFNKLN 424
SHASID + R+ER+FPEDL+RLC GIEN+ DL DL A++ + ++V + LFN ++
Sbjct: 344 SHASIDAKTREEREFPEDLIRLCIGIENVDDLIDDLTKALLKSGAVKVNYKDE-LFNAVD 402
>gb|EDU44308.1| cystathionine beta-lyase [Pyrenophora tritici-repentis Pt-1C-BFP]
Length = 451
Score = 370 bits (949), Expect = e-100, Method: Composition-based stats.
Identities = 205/411 (49%), Positives = 261/411 (63%), Gaps = 26/411 (6%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
L T +V T S +DQ++AS P+Y S TFK + YDY+RSGNPTR+ L+ + K+
Sbjct: 43 LMTELVYTES-SDQYNASSVPIYQSATFKQESATGGGGEYDYTRSGNPTRTHLERHLAKI 101
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
L VSSGM ALDVI R LL D ++ GDDLYGGT RLL +
Sbjct: 102 MNA--NRALVVSSGMGALDVITR---LLRPGDE----VVTGDDLYGGTNRLLKYLSTHGG 152
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
+ H+DT++ EK + V +K VLLE+PTNPL K+ DIP I +P V V
Sbjct: 153 IIVHHIDTTNPEKVRAVVN--EKTAMVLLETPTNPLIKICDIPAIASIAHTANPTAIVAV 210
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DNTMMS + NPL L G D+VYES TKYL+GHHDLM GVI + +L+F IN++G
Sbjct: 211 DNTMMSPMLLNPLDL--GSDIVYESGTKYLSGHHDLMAGVIAINDSALGDRLFFTINASG 268
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
GLSP DSWLL+RG+KTLGVR+ +QQ NAM +A +LE S GF K R+ GL+S
Sbjct: 269 CGLSPFDSWLLLRGIKTLGVRMEKQQANAMRIATFLE-SHGF---------KVRYPGLKS 318
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P + LH S G GAVLSFETG S+R+V S +L W ++VSFGCVNSL+SMPC+MS
Sbjct: 319 HPQYDLHWSMARGAGAVLSFETGDVNISERIVESARL--WGISVSFGCVNSLISMPCRMS 376
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENG 416
HASID + RKER+ PED++RLC GIE+ DL DL A+V A + + G
Sbjct: 377 HASIDEKTRKERNMPEDIIRLCVGIEDPEDLLDDLSRALVQAGAVNITTEG 427
>ref|XP_001558791.1| hypothetical protein BC1G_02862 [Botryotinia fuckeliana B05.10]
gb|AAF20155.1|AF211176_1 cystathionine beta-lyase [Botryotinia fuckeliana]
gb|EDN33184.1| hypothetical protein BC1G_02862 [Botryotinia fuckeliana B05.10]
Length = 459
Score = 370 bits (949), Expect = e-100, Method: Composition-based stats.
Identities = 205/411 (49%), Positives = 265/411 (64%), Gaps = 27/411 (6%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
L T +V T ++ DQ+ AS P+Y S TFK +L ++ YDY+RSGNPTR+ L+ + K+
Sbjct: 51 LATELVYTETK-DQYGASSMPIYQSATFKQNLAGGGSE-YDYTRSGNPTRTHLERHLAKI 108
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
L V SGM ALDVI R VL G + +I GDDLYGGT RLL + +
Sbjct: 109 MNA--NRALVVGSGMGALDVITR--VLRPGDE-----VITGDDLYGGTNRLLTYLAANTG 159
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
+ HVDT+ +K K V K VLLE+PTNPL K+VDI I R ++ VVV
Sbjct: 160 IIVHHVDTTTPDKVKAVLGP--KTAMVLLETPTNPLIKIVDIATIARTAHELNEKALVVV 217
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DNTM+S + CNPL L G D+VYES TKYL+GHHD+M GV+ P I K+YF INSTG
Sbjct: 218 DNTMLSPMLCNPLDL--GADIVYESGTKYLSGHHDIMAGVLAFNDPAIGDKMYFTINSTG 275
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
GLSP DS+LL+RG+KTL +R+ +QQ NA +A +LE GF + R+ GL+S
Sbjct: 276 CGLSPNDSFLLMRGIKTLAIRMERQQTNAQAIAEFLETH-GF---------RVRYPGLKS 325
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P + LH S G GAVLSFETG S+R+V + KL W ++VSFGCVNSL+SMPC+MS
Sbjct: 326 HPQYDLHWSMARGAGAVLSFETGDVALSERIVEAAKL--WGISVSFGCVNSLISMPCQMS 383
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENG 416
HASID + RKER PED++RLC GIE++ DL DL A+V A ++V +G
Sbjct: 384 HASIDAKTRKERQMPEDIIRLCVGIEDVNDLIDDLSRALVQAGAVKVTLDG 434
>ref|XP_719662.1| cystathionine beta-lyase [Candida albicans SC5314]
ref|XP_719538.1| cystathionine beta-lyase [Candida albicans SC5314]
gb|EAL00658.1| hypothetical protein CaO19.2092 [Candida albicans SC5314]
gb|EAL00786.1| hypothetical protein CaO19.9639 [Candida albicans SC5314]
Length = 404
Score = 367 bits (941), Expect = 1e-99, Method: Composition-based stats.
Identities = 206/407 (50%), Positives = 271/407 (66%), Gaps = 29/407 (7%)
Query: 18 DQHSASVPPVYLSTTFKV-DLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
DQ++ASVPP+Y S TFK L+N YDY+RSGNPTR+ LQ+ I K+ + E+ AV
Sbjct: 20 DQYNASVPPLYQSATFKQPSLSN--MGEYDYTRSGNPTRTHLQNHIAKIMKA--EHAFAV 75
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
SSGM LDVI R LL D +IAGDDLYGGT RLL + ++ V+ H DT++
Sbjct: 76 SSGMGCLDVITR---LLKPGDE----VIAGDDLYGGTHRLLTYLSKKGDIVAHHYDTTNT 128
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
E K+ +K + LESPTNPL KVVD+ I + D VV DNTMMS +
Sbjct: 129 ELIKSKIN--NKTKMIFLESPTNPLIKVVDVKSIADHAHKANRDIVVVFDNTMMSPVLMT 186
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
PL L G D+ YESATKYLNGHHD+M GVI +++ +A +LY++INSTG GLSP D WLL
Sbjct: 187 PLDL--GVDIQYESATKYLNGHHDIMAGVIATRSSSLAEQLYYIINSTGCGLSPFDCWLL 244
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
RGLKTL +R+ +QQ+N + +A +LEN GF K R+ GL+S+P ++LH S
Sbjct: 245 SRGLKTLAIRVEKQQQNCIRIAKFLEN-IGF---------KVRYPGLKSHPQYELHSSMC 294
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
+G GAVLSFETGS S+++V + I+ + VSFGCVNSL+SMPCKMSHASID + R+E
Sbjct: 295 SGYGAVLSFETGSVRLSEKIVENT--DIFGIAVSFGCVNSLISMPCKMSHASIDAKTREE 352
Query: 377 RDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLFNKL 423
R+FPEDL+RLC GIEN DL DL A++ + ++V + + L+N +
Sbjct: 353 REFPEDLIRLCIGIENCDDLIDDLTKALLRSGAVKVNDRDE-LYNAV 398
>ref|XP_001223755.1| hypothetical protein CHGG_04541 [Chaetomium globosum CBS 148.51]
gb|EAQ87922.1| hypothetical protein CHGG_04541 [Chaetomium globosum CBS 148.51]
Length = 444
Score = 366 bits (940), Expect = 2e-99, Method: Composition-based stats.
Identities = 206/411 (50%), Positives = 264/411 (64%), Gaps = 27/411 (6%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
L T +V T S+ DQ+ +S P+Y S TFK +N YDY+RSGNPTR+ L+ + K+
Sbjct: 46 LATELVYTESK-DQYGSSSIPIYQSATFKQTSSN-GGNEYDYTRSGNPTRTHLERHLAKI 103
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
+ LAV SGM ALDVI R LL D +I GDDLYGGT RLL + K
Sbjct: 104 MNATR--ALAVGSGMGALDVITR---LLKPGDE----VITGDDLYGGTNRLLTYLKNNQG 154
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
V HVDT++ + TV DK VLLE+PTNPL K+VDIP I R + VVV
Sbjct: 155 VVVHHVDTTNADSVTTVIS--DKTAMVLLETPTNPLIKIVDIPSIARATHEANSKALVVV 212
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DNTM+S + NPL + G D+VYES TKYL+GHHD+M GVI PE+ K+YF IN+TG
Sbjct: 213 DNTMLSPMLLNPLDI--GADIVYESGTKYLSGHHDIMAGVIACNDPELGDKMYFTINATG 270
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
GLSP DS+LL+RG+KTL +R+ +QQ NA +A +LE S GF + R+ GL+S
Sbjct: 271 CGLSPNDSFLLMRGIKTLAIRMEKQQGNAQRIAEFLE-SHGF---------RVRYPGLKS 320
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P + LH S G GAVLSFETG S+R+V + +L W ++VSFGCVNSL+SMPC+MS
Sbjct: 321 HPQYDLHWSMARGAGAVLSFETGDVALSERIVEAARL--WGISVSFGCVNSLISMPCRMS 378
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENG 416
HASID + R+ER PED++RLC GIE+ DL DL A+V A + V +G
Sbjct: 379 HASIDAKTRQERQMPEDIIRLCVGIEDADDLIDDLSRALVQAGAVTVSLDG 429
>ref|XP_001825972.1| hypothetical protein [Aspergillus oryzae RIB40]
dbj|BAE64839.1| unnamed protein product [Aspergillus oryzae]
Length = 441
Score = 366 bits (939), Expect = 3e-99, Method: Composition-based stats.
Identities = 207/405 (51%), Positives = 260/405 (64%), Gaps = 27/405 (6%)
Query: 8 TVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYR 67
T +V T S DQ++AS P+Y S TFK + YDY+RSGNPTR+ L+ + K+
Sbjct: 52 TELVYTDS-GDQYNASSVPIYQSATFK-QTSGGGGGEYDYTRSGNPTRTHLERHLAKV-- 107
Query: 68 VPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAV 127
+ + L VSSGM ALDVI R LL D ++ GDDLYGGT RLL + +
Sbjct: 108 MSAQRALVVSSGMAALDVITR---LLRPGDE----VVTGDDLYGGTHRLLKYLSTNGGII 160
Query: 128 SVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDN 187
HVDT+ EK + V +K VLLE+PTNPL K+VDIP+I ++ V VDN
Sbjct: 161 VHHVDTTQPEKVREVLN--EKTAMVLLETPTNPLIKIVDIPQIATAAHEVNSTCLVAVDN 218
Query: 188 TMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAG 247
TMMS + NPL+L G D+VYES TKYL+GHHDLM GVI + +LYF IN++G G
Sbjct: 219 TMMSPMLLNPLEL--GADIVYESGTKYLSGHHDLMAGVIAVNDLALGERLYFPINASGCG 276
Query: 248 LSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNP 307
LSP DSWLL+RG+KTL VR+ QQQ NA +A +LE S GF K R+ GLRS+P
Sbjct: 277 LSPFDSWLLMRGVKTLKVRMDQQQANAQRIAEFLE-SHGF---------KVRYPGLRSHP 326
Query: 308 DFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHA 367
+ LH S G GAVLSFETG S+R+V S KL WA++VSFGCVNSL+SMPC+MSHA
Sbjct: 327 QYDLHHSMARGAGAVLSFETGDVGVSERIVESAKL--WAISVSFGCVNSLISMPCRMSHA 384
Query: 368 SIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEV 412
SID + R+ER PEDL+RLC GIE+ DL DL A+V A + +
Sbjct: 385 SIDAKTRQERAMPEDLIRLCVGIEDADDLIDDLTRALVQAGAVNL 429
>ref|XP_456620.1| hypothetical protein DEHA0A06897g [Debaryomyces hansenii CBS767]
emb|CAG84576.1| unnamed protein product [Debaryomyces hansenii CBS767]
Length = 404
Score = 365 bits (937), Expect = 4e-99, Method: Composition-based stats.
Identities = 201/407 (49%), Positives = 272/407 (66%), Gaps = 27/407 (6%)
Query: 18 DQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAVS 77
DQH+ASVPP+Y S TFK + + D YDY+RSGNPTR+ LQ+ + K+ + ++ AV+
Sbjct: 20 DQHNASVPPLYQSATFKQN-SLSDMGEYDYTRSGNPTRTYLQNHMAKIMKA--KHAFAVT 76
Query: 78 SGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFE 137
SGM LDVI R +L G + ++AGDDLYGGT RLL + ++ H DT++ E
Sbjct: 77 SGMGCLDVITR--ILKPGDE-----VLAGDDLYGGTNRLLTYLNKKGDLKVQHWDTTNTE 129
Query: 138 KFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCNP 197
F + + K+ + LESPTNPL KV D+ I + +PD VV DNTMMS + P
Sbjct: 130 LFTSKITNNTKM--IFLESPTNPLIKVCDVKSITDYAHRKNPDVVVVFDNTMMSPILMTP 187
Query: 198 LQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLLV 257
L L G D+ YESATKYLNGHHD+M GVI ++ ++A K+YFVINSTG GLSP DSWLL
Sbjct: 188 LDL--GVDIQYESATKYLNGHHDIMAGVIATRDAKLAEKVYFVINSTGCGLSPFDSWLLS 245
Query: 258 RGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFNN 317
RGL+TL VR+ +QQ+N +A +L +S GF + R+ GL+S+P ++LH S
Sbjct: 246 RGLRTLAVRVERQQQNCQKIAEFL-SSIGF---------RVRYPGLKSHPQYELHASMCK 295
Query: 318 GPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKER 377
G GAV+SFETGS + S+++V + I+ + VSFGCVNSL+SMPCKMSHASID + R+ER
Sbjct: 296 GAGAVISFETGSIKTSEKIVENT--DIFGIAVSFGCVNSLISMPCKMSHASIDAKTREER 353
Query: 378 DFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLFNKLN 424
DFPEDL+RLC GIEN DL DL A++ + +++ + LFN ++
Sbjct: 354 DFPEDLIRLCIGIENSDDLINDLTKALLKSGAVKINSKDE-LFNAVS 399
>ref|XP_502248.1| hypothetical protein [Yarrowia lipolytica]
emb|CAG80434.1| unnamed protein product [Yarrowia lipolytica CLIB122]
Length = 434
Score = 365 bits (936), Expect = 5e-99, Method: Composition-based stats.
Identities = 203/419 (48%), Positives = 269/419 (64%), Gaps = 27/419 (6%)
Query: 7 DTVVVNTGSQNDQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
+ V + G D+ H +S P++ + TFK + + + YDY+RSGNPTRS L+ + K+
Sbjct: 42 ELVYTDAGEGADKYHRSSSVPIFQTATFKQE-SLSNMGEYDYTRSGNPTRSALERHLAKI 100
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
+ LAVSSGMTALDV+ R LL D ++ GDDLYGGT RLL + K+ +
Sbjct: 101 --MGASRALAVSSGMTALDVVTR---LLKPGDE----VVTGDDLYGGTNRLLTYLKENAG 151
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
+ HVDT++ E VF K VLLESPTNPL KV DI + +P+ V V
Sbjct: 152 IIVHHVDTTNLESASKVFGP--KTALVLLESPTNPLIKVCDIQGLAAAAHAGNPNALVCV 209
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DNTM+S L PL+L G D+VYES TKYL+GHHD+M GV+ + ++ +L+F IN++G
Sbjct: 210 DNTMLSPLLMRPLEL--GADIVYESGTKYLSGHHDIMAGVLAVRENKVGDRLFFTINASG 267
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
GLSP DSWLL+RG+KTL VRL +QQRNA +A +L + GF K RF GL+S
Sbjct: 268 CGLSPFDSWLLLRGIKTLSVRLEKQQRNAQQVAEFLHEA-GF---------KVRFPGLKS 317
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P + LH + G GAVLSFETGS S+++V + + IW ++VSFGCVNSL+SMPCKMS
Sbjct: 318 HPQYDLHWKQSRGAGAVLSFETGSVALSEKIVEAAR--IWGISVSFGCVNSLISMPCKMS 375
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLFNKLN 424
HASID + RKERDFPEDL+RLC GIE+ DL DL A+V A + + +G+ N N
Sbjct: 376 HASIDEKTRKERDFPEDLIRLCVGIEDPDDLIDDLKTALVKAGAVTIGIDGQLTNNVSN 434
>ref|XP_001486404.1| hypothetical protein PGUG_02075 [Pichia guilliermondii ATCC 6260]
gb|EDK37977.1| hypothetical protein PGUG_02075 [Pichia guilliermondii ATCC 6260]
Length = 403
Score = 364 bits (935), Expect = 7e-99, Method: Composition-based stats.
Identities = 210/420 (50%), Positives = 276/420 (65%), Gaps = 30/420 (7%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKV-DLNNEDAQNYDYSRSGNPTRSVLQHQIGK 64
L+T +V + S DQ++ASV P+Y S TFK L+N YDY+RSGNPTR+ LQ+ I K
Sbjct: 8 LETELVLSKS-TDQYNASVAPLYQSATFKQPSLSN--MGEYDYTRSGNPTRTHLQNHIAK 64
Query: 65 LYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQS 124
+ R + AV+SGM LDVI R LL+ D +IAGDDLYGGT RLL + +
Sbjct: 65 IMRA--NHAFAVTSGMGCLDVITR---LLSPGDE----VIAGDDLYGGTHRLLTYLNNKG 115
Query: 125 HAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVV 184
H DT++ E + S K+ + LESPTNPL KV D+ I R I+PD VV
Sbjct: 116 DLKVHHYDTTNTELLVSKIHSGTKM--IFLESPTNPLIKVCDVRTITREAHKINPDIVVV 173
Query: 185 VDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINST 244
DNTMMS + PL G D+ YESATKYLNGHHD+M GV+ +++ +A K+Y+VINST
Sbjct: 174 FDNTMMSPVLMTPLDF--GVDIQYESATKYLNGHHDIMAGVLATRSAALAEKIYYVINST 231
Query: 245 GAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLR 304
G GLSP DSWLL RGL+TL VR+ +QQ+N + +A +L N GF K R+ G++
Sbjct: 232 GCGLSPFDSWLLSRGLRTLAVRVERQQQNCVRIAEFLAN-IGF---------KVRYPGIK 281
Query: 305 SNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKM 364
S+P + LH S G GAVLSFETGS + S+++V S + I+ + VSFGCVNSL+SMPCKM
Sbjct: 282 SHPQYDLHASMCKGAGAVLSFETGSIKVSEKIVESTE--IFGIAVSFGCVNSLISMPCKM 339
Query: 365 SHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLFNKLN 424
SHASID + R+ERDFPEDL+RLC GIEN DL DL A++ + +++ E + LFN ++
Sbjct: 340 SHASIDAKTREERDFPEDLIRLCIGIENCDDLIDDLTRALLRSGAVKLNERDE-LFNAVS 398
>ref|XP_367149.1| hypothetical protein MGG_07074 [Magnaporthe grisea 70-15]
gb|EDK03766.1| hypothetical protein MGG_07074 [Magnaporthe grisea 70-15]
Length = 454
Score = 364 bits (935), Expect = 7e-99, Method: Composition-based stats.
Identities = 199/411 (48%), Positives = 261/411 (63%), Gaps = 26/411 (6%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
L T +V T ++ DQ+ AS P+Y S TFK YDY+RSGNPTR+ L+ + K+
Sbjct: 45 LATELVYTETK-DQYGASSIPIYQSATFKQSSAAGGNSEYDYTRSGNPTRTHLERHMAKI 103
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
LAV SGM ALDVI R LL D +I GDDLYGGT RLL +
Sbjct: 104 MNA--NRALAVGSGMGALDVITR---LLRPGDE----VITGDDLYGGTNRLLTYLSANQG 154
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
+ H+DT+D ++ DK VLLE+PTNPL K+VD+ I R + VVV
Sbjct: 155 IIVHHIDTTDIDRVAATVS--DKTAMVLLETPTNPLIKIVDVATIARAAHDRNSKALVVV 212
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DNTM+S + CNPL L G D+VYES TKYL+GHHD+M G++ +A ++YF +N+TG
Sbjct: 213 DNTMLSPMLCNPLDL--GADIVYESGTKYLSGHHDIMSGIVACNDAALADRMYFTVNATG 270
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
GLSP DS+LL+RG+KTL VR+ +QQ NA +A +LE S GF + R+ GL+S
Sbjct: 271 CGLSPNDSFLLMRGIKTLAVRMEKQQANAQRIAEFLE-SHGF---------RVRYPGLKS 320
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P + LH S G GAVLSFETG E S+R+V + +L WA++VSFGCVNSL+SMPC+MS
Sbjct: 321 HPQYDLHWSMARGAGAVLSFETGDAELSQRIVEAARL--WAISVSFGCVNSLISMPCQMS 378
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENG 416
HASID + RKER PED++RLC GIE++ DL DL A+V A + + +G
Sbjct: 379 HASIDAKTRKERQMPEDIIRLCVGIEDVQDLIDDLSRALVTAGAVSITVDG 429
>ref|XP_001274827.1| cystathionine beta-lyase MetG [Aspergillus clavatus NRRL 1]
gb|EAW13401.1| cystathionine beta-lyase MetG [Aspergillus clavatus NRRL 1]
Length = 447
Score = 363 bits (931), Expect = 2e-98, Method: Composition-based stats.
Identities = 205/400 (51%), Positives = 259/400 (64%), Gaps = 26/400 (6%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
+DQ++AS P+Y S TFK + YDY+RSGNPTR+ L+ + K+ + + L V
Sbjct: 61 SDQYNASSVPIYQSATFK-QTSGSGGGEYDYTRSGNPTRTHLERHLAKI--MSAQRALVV 117
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
SSGM ALDVI R LL D ++ GDDLYGG+ RLL + + HVDT+
Sbjct: 118 SSGMAALDVISR---LLRPGDE----VVTGDDLYGGSHRLLKYLSTNGGIIVHHVDTTQP 170
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
EK + V + K VLLE+PTNPL K+VDIP+I ++P V VDNTMMS L N
Sbjct: 171 EKVREVLSA--KTAMVLLETPTNPLIKIVDIPQIAAAAHELNPSCLVAVDNTMMSPLLLN 228
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
PL L G D+VYES TKYL+GHHDLM GVI + +LYF IN++G GLSP DSWLL
Sbjct: 229 PLDL--GADIVYESGTKYLSGHHDLMAGVIAVNDLALGERLYFPINASGCGLSPFDSWLL 286
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
+RG+KTL VR+ QQQ NA +A +LE S GF K R+ GLRS+P ++LH S
Sbjct: 287 MRGVKTLKVRMDQQQTNAQRIAEFLE-SHGF---------KVRYPGLRSHPQYELHHSMA 336
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
G GAVLSFETG S+R+V S KL WA++VSFGCVNSL+SMPC+MSHASID + R E
Sbjct: 337 RGAGAVLSFETGDVGVSERIVESAKL--WAISVSFGCVNSLISMPCRMSHASIDAKTRAE 394
Query: 377 RDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENG 416
R PEDL+RLC GIE++ DL DL A+V A + + +G
Sbjct: 395 RAMPEDLIRLCVGIEDVDDLLDDLRRALVQAGAVNITLDG 434
>gb|EEH38678.1| cystathionine beta-lyase [Paracoccidioides brasiliensis Pb01]
Length = 447
Score = 363 bits (931), Expect = 2e-98, Method: Composition-based stats.
Identities = 211/421 (50%), Positives = 260/421 (61%), Gaps = 45/421 (10%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
NDQ ++S P+Y S TFK + YDY+RSGNPTR+ L+ + K+ + E LAV
Sbjct: 63 NDQFNSSSMPIYQSATFK-QTSGSGGGEYDYTRSGNPTRTHLERHLAKI--MSAERALAV 119
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
SSGM ALDVI R LL D +I GDDLYGGT RLL + + HVDT+
Sbjct: 120 SSGMAALDVITR---LLTPGDE----VITGDDLYGGTNRLLKYLSTHGGIIVHHVDTTRP 172
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
EK V + K+ VLLE+PTNPL K+VDIPR+ +P+ V VDNTM+S L
Sbjct: 173 EKVAEVLSAATKL--VLLETPTNPLIKIVDIPRVAALAHEANPNALVAVDNTMLSPLL-- 228
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
LN G D+VYES TKYL+GHHDLM GVI + KLY+ INS+G GLSP DSWLL
Sbjct: 229 LNPLNLGADIVYESGTKYLSGHHDLMAGVIAVNDISLGEKLYYPINSSGCGLSPFDSWLL 288
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
+RG+KTL VR+ QQQ NA +A +LE GF + R+ GL+S+P + LH S
Sbjct: 289 LRGVKTLKVRMEQQQSNAQRIAEFLEEH-GF---------RVRYPGLKSHPQYGLHHSMA 338
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
G GAVLSFETG S+R+V S KL WA++VSFGCVNSL+SMPC+MSHASID + RKE
Sbjct: 339 RGSGAVLSFETGDVTISERIVESAKL--WAISVSFGCVNSLISMPCRMSHASIDAKTRKE 396
Query: 377 RDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLFNKLNKNLAVNTTIDDL 436
RD PEDL+RLC GIE++ DL DL A+V A AVN T+DD
Sbjct: 397 RDMPEDLIRLCVGIEDVDDLIDDLRRALVQAS-------------------AVNLTLDDF 437
Query: 437 H 437
Sbjct: 438 Q 438
>ref|XP_001382256.1| cystathionine beta-lyase [Pichia stipitis CBS 6054]
gb|ABN64227.1| cystathionine beta-lyase [Pichia stipitis CBS 6054]
Length = 411
Score = 363 bits (931), Expect = 2e-98, Method: Composition-based stats.
Identities = 209/422 (49%), Positives = 276/422 (65%), Gaps = 30/422 (7%)
Query: 2 PIK--RLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQ 59
PIK L+T +V S DQ+++SV P+Y S TFK D + + YDY+RSGNPTR+ LQ
Sbjct: 10 PIKTYSLETELVFNKSA-DQYNSSVAPLYQSATFKQD-SLSNMGEYDYTRSGNPTRTHLQ 67
Query: 60 HQIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNF 119
+ + ++ R ++ AV+SGM LDVI R LL D +IAGDDLYGGT RLL +
Sbjct: 68 NHLARIMRA--KHTFAVTSGMGCLDVITR---LLKPGDE----VIAGDDLYGGTNRLLTY 118
Query: 120 FKQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISP 179
+ + H DT++ E K+ K+ + LESPTNPL KVVD+ I ++P
Sbjct: 119 LHNKGDVKAFHYDTTNTELIKSKITRATKM--IFLESPTNPLIKVVDVRSISEHAHKVNP 176
Query: 180 DTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYF 239
D VV DNTMMS + PL L G D+ YESATKYLNGHHD+M GVI +++ + A +LY
Sbjct: 177 DVVVVFDNTMMSPIFMTPLDL--GVDIQYESATKYLNGHHDIMAGVIATRSDKFAEQLYN 234
Query: 240 VINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTR 299
VINSTG GLSP DSWLL RGL+TL +R+ +QQ+N + +A +L+N GF K R
Sbjct: 235 VINSTGCGLSPFDSWLLSRGLRTLAIRVERQQQNCINVAEFLKN-IGF---------KVR 284
Query: 300 FVGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLS 359
+ GL+ +P +LH S G GAVLSFETG+ + S+R+V S + I+ + VSFGCVNSL+S
Sbjct: 285 YPGLKDHPQHELHNSMCRGYGAVLSFETGNIKLSERIVESTE--IFGIAVSFGCVNSLIS 342
Query: 360 MPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYL 419
MPCKMSHASID + R+ERDFPEDL+RLC GIEN DL DL A++ + + + E + L
Sbjct: 343 MPCKMSHASIDAKTREERDFPEDLIRLCIGIENCDDLIDDLTKALLKSGAVRINERDE-L 401
Query: 420 FN 421
FN
Sbjct: 402 FN 403
>ref|XP_664655.1| hypothetical protein AN7051.2 [Aspergillus nidulans FGSC A4]
gb|EAA61697.1| hypothetical protein AN7051.2 [Aspergillus nidulans FGSC A4]
Length = 458
Score = 363 bits (931), Expect = 2e-98, Method: Composition-based stats.
Identities = 203/388 (52%), Positives = 255/388 (65%), Gaps = 26/388 (6%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
NDQ++AS P+Y S TFK ++E YDY+RSGNPTR+ L+ + K+ + + L V
Sbjct: 48 NDQYNASSVPIYQSATFKQS-SHEGGGEYDYTRSGNPTRTHLERHLAKI--MSAQRALVV 104
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
SSGM ALDVI R LL D ++ GDDLYGGT RLL + + HVDT++
Sbjct: 105 SSGMAALDVITR---LLRPGDE----VVTGDDLYGGTNRLLKYLSTNGGIIVHHVDTTNP 157
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
+K K V DK VLLE+PTNPL K+VDIP I +P+ V+VDNTMMS L
Sbjct: 158 DKVKEVLT--DKTAMVLLETPTNPLIKIVDIPTIAAASHEANPNCLVIVDNTMMSPLL-- 213
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
L G DVVYES TKYL+GHHD+M GVI P + +LYF IN++G GLSP DSWLL
Sbjct: 214 LSPLELGADVVYESGTKYLSGHHDVMAGVIAVNDPALGERLYFPINASGCGLSPFDSWLL 273
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
+RG+KTL VR+ QQQ NA +A +LE S GF K R+ GLRS+P + LH S
Sbjct: 274 MRGVKTLKVRMDQQQANAQRIAEFLE-SHGF---------KVRYPGLRSHPQYDLHHSMA 323
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
G GAVLSFETG S+R+V++ KL WA++VSFGCVNSL+S+PC+MSHASID + RKE
Sbjct: 324 RGAGAVLSFETGDVSVSERIVANAKL--WAISVSFGCVNSLISLPCRMSHASIDAKTRKE 381
Query: 377 RDFPEDLVRLCCGIENIVDLKKDLLAAM 404
R PEDL+RLC GIE++ DL DL A+
Sbjct: 382 RAMPEDLIRLCVGIEDVDDLIDDLRRAV 409
>ref|XP_001910364.1| unnamed protein product [Podospora anserina]
emb|CAP71499.1| unnamed protein product [Podospora anserina]
Length = 441
Score = 363 bits (931), Expect = 2e-98, Method: Composition-based stats.
Identities = 205/411 (49%), Positives = 262/411 (63%), Gaps = 27/411 (6%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
L T +V T S+ DQ+ AS P+Y S TFK +N YDY+RSGNPTR+ L+ + K+
Sbjct: 43 LATELVYTDSK-DQYGASSIPIYQSATFKQTSSN-GGNEYDYTRSGNPTRTHLERHLAKI 100
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
+ LAV SGM ALDVI R LL D +I GDDLYGGT RLL + K
Sbjct: 101 MNATR--CLAVGSGMGALDVITR---LLKPGDE----VITGDDLYGGTNRLLTYLKNNQG 151
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
V HVDT++ + K V +K VLLE+PTNPL K+VD+ I R + VVV
Sbjct: 152 VVVHHVDTTNVDAVKEVIT--EKTAMVLLETPTNPLIKIVDVASIARASHEANSKALVVV 209
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DNTM+S + CNPL L G D+ YES TKYL+GHHD+M GVI EI K+YF IN+TG
Sbjct: 210 DNTMLSPMLCNPLDL--GADISYESGTKYLSGHHDIMAGVIAVNDAEIGDKMYFTINATG 267
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
GLSP DS+LL+RG+KTL +R+ +QQ +A +A +LE S GF K R+ GLRS
Sbjct: 268 CGLSPNDSFLLMRGVKTLAIRMEKQQTSAQRIAEFLE-SHGF---------KVRYPGLRS 317
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P + LH S G GAVLSFETG S+R+V + +L W ++VSFGCVNSL+SMPC+MS
Sbjct: 318 HPQYDLHWSMARGAGAVLSFETGDVALSERIVEAARL--WGISVSFGCVNSLISMPCRMS 375
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENG 416
HASID + R ER PED++RLC GIE++ DL DL A+V A + + +G
Sbjct: 376 HASIDAKTRAERQMPEDIIRLCVGIEDVDDLIDDLTRALVQAGAVTLTIDG 426
>gb|ABM92783.1| putative cystathionine beta-lyase Met6p [Pichia angusta]
Length = 384
Score = 362 bits (929), Expect = 3e-98, Method: Composition-based stats.
Identities = 201/399 (50%), Positives = 269/399 (67%), Gaps = 29/399 (7%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKV-DLNNEDAQNYDYSRSGNPTRSVLQHQIGK 64
L+T +V+ +N H+AS+ P Y+S TFK DL ++ YDY+RSGNPTRS LQ+ + K
Sbjct: 7 LETELVHVDDKN-THNASITPAYMSATFKAKDL--DEMGPYDYTRSGNPTRSALQNHLSK 63
Query: 65 LYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQS 124
+ + ++V A++SGM ALDVI+R +L G + +IAGDDLYGGT RLL + K +
Sbjct: 64 IMKA--KHVYALNSGMAALDVIVR--ILSPGDE-----VIAGDDLYGGTDRLLTYIKTFN 114
Query: 125 HAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVV 184
H H DT++ E + K+ V+LESPTNPL K+ D+ I +P+ VV
Sbjct: 115 HIKVGHYDTTNLELITSKITKDTKM--VVLESPTNPLIKICDLKAIADHAHKQNPNCVVV 172
Query: 185 VDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINST 244
DNTMM+ L +PL+L G D+ YESATKYLNGHHD+M GVI + + E+A K++FVIN+T
Sbjct: 173 FDNTMMTPLFMSPLEL--GADIQYESATKYLNGHHDIMAGVIATNSDELAKKVFFVINAT 230
Query: 245 GAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLR 304
GAG++P DSWLL+RGLKTL +R+ +QQ NAM +A WLE ++ K R+ GL
Sbjct: 231 GAGIAPFDSWLLLRGLKTLALRVERQQENAMKIAKWLE----------SQNVKVRYPGLE 280
Query: 305 SNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKM 364
S+P ++LHK G GAVLSFETG SKR++++ I++VTVSFG V SL+S+PC M
Sbjct: 281 SHPQYELHKKQCKGAGAVLSFETGDVAVSKRIIAA--CEIYSVTVSFGYVASLISLPCLM 338
Query: 365 SHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAA 403
SHASI E RKERDFPEDL+RLC GIE+ DL +DL A
Sbjct: 339 SHASISAETRKERDFPEDLIRLCAGIESADDLIEDLAHA 377
>gb|EEH45004.1| cystathionine beta-lyase [Paracoccidioides brasiliensis Pb18]
Length = 445
Score = 360 bits (924), Expect = 2e-97, Method: Composition-based stats.
Identities = 204/396 (51%), Positives = 254/396 (64%), Gaps = 26/396 (6%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
NDQ ++S P+Y S TFK + YDY+RSGNPTR+ L+ + K+ + E LAV
Sbjct: 63 NDQFNSSSMPIYQSATFK-QTSGSGGGEYDYTRSGNPTRTHLERHLAKI--MSAERTLAV 119
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
SSGM ALDVI R LL D +I GDDLYGGT RLL + + HVDT+
Sbjct: 120 SSGMAALDVITR---LLTPGDE----VITGDDLYGGTNRLLKYLSTHGGIIVHHVDTTRP 172
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
EK V + K+ VLLE+PTNPL K+VDIP++ +P V VDNTM+S L
Sbjct: 173 EKVAEVLSAATKL--VLLETPTNPLIKIVDIPQVAALAHEANPGALVAVDNTMLSPLL-- 228
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
LN G D+VYES TKYL+GHHDLM GVI + KLY+ INS+G GLSP DSWLL
Sbjct: 229 LNPLNLGADIVYESGTKYLSGHHDLMAGVIAVNDISLGEKLYYPINSSGCGLSPFDSWLL 288
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
+RG+KTL VR+ QQQ NA +A +LE GF + R+ GL+S+P + LH S
Sbjct: 289 LRGVKTLKVRMEQQQSNAQRIAEFLEEH-GF---------RVRYPGLKSHPQYTLHHSMA 338
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
G GAVLSFETG S+R+V S KL WA++VSFGCVNSL+SMPC+MSHASID + RKE
Sbjct: 339 RGSGAVLSFETGDVTISERIVESAKL--WAISVSFGCVNSLISMPCRMSHASIDAKTRKE 396
Query: 377 RDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEV 412
RD PEDL+RLC GIE++ DL DL A+V A + +
Sbjct: 397 RDMPEDLIRLCVGIEDVDDLIDDLRRALVQASAVNL 432
>ref|XP_962657.1| cystathionine beta-lyase [Neurospora crassa OR74A]
gb|AAK94039.1|AF401237_1 cystathionine beta-lyase [Neurospora crassa]
gb|EAA33421.1| cystathionine beta-lyase [Neurospora crassa OR74A]
Length = 457
Score = 357 bits (917), Expect = 8e-97, Method: Composition-based stats.
Identities = 202/411 (49%), Positives = 262/411 (63%), Gaps = 27/411 (6%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
L T +V T ++ DQ+ AS P+Y S TFK +N ++ YDY+RSGNPTR+ L+ + K+
Sbjct: 45 LATELVYTETK-DQYGASSIPIYQSATFKQSSSNGGSE-YDYTRSGNPTRTHLERHLAKI 102
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
L+VSSGM ALDVI R LL D +I GDDLYGGT RLL + K
Sbjct: 103 MNA--NRCLSVSSGMGALDVITR---LLKPGDE----VITGDDLYGGTNRLLTYLKNNQG 153
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
+ HVDT++ E + + K VLLE+PTNPL K+ DIP I R + VVV
Sbjct: 154 VIVHHVDTTNVESVRQIISP--KTTMVLLETPTNPLIKICDIPTIARITHEANEKAVVVV 211
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DNTM+S + NPL + G D+VYES TKYL+GHHD+M GVI E+ KLYF IN+TG
Sbjct: 212 DNTMLSPMLFNPLDV--GADIVYESGTKYLSGHHDIMAGVIAVNDTELGDKLYFTINATG 269
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
GLSP DS+LL+RG+KTL +R+ +QQ NA +A +LE S GF K R+ GL+S
Sbjct: 270 CGLSPNDSFLLMRGVKTLAIRMEKQQANAQRIAEFLE-SHGF---------KVRYPGLKS 319
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P + LH S G GAVLSFETG S+R+V + +L W ++VSFGCVNSL+SMPC+MS
Sbjct: 320 HPQYDLHWSMARGAGAVLSFETGDVALSERIVEAARL--WGISVSFGCVNSLISMPCRMS 377
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENG 416
HASID + R ER PED++RLC GIE+ DL DL A+V A + + +G
Sbjct: 378 HASIDAKTRAERQMPEDIIRLCVGIEDADDLIDDLSRALVQAGAVTLTVDG 428
>ref|XP_001211424.1| cystathionine beta-lyase [Aspergillus terreus NIH2624]
gb|EAU37208.1| cystathionine beta-lyase [Aspergillus terreus NIH2624]
Length = 432
Score = 357 bits (916), Expect = 1e-96, Method: Composition-based stats.
Identities = 202/388 (52%), Positives = 247/388 (63%), Gaps = 26/388 (6%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
NDQ++AS P+Y S TFK + YDY+RSGNPTR+ L+ + K+ + + L V
Sbjct: 56 NDQYNASSVPIYQSATFKQSSGGGGGE-YDYTRSGNPTRTHLERHLAKV--MSAQRALVV 112
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
SSGM ALDVI R LL D ++ GDDLYGGT RLL + + HVDT+D
Sbjct: 113 SSGMAALDVITR---LLRPGDE----VVTGDDLYGGTNRLLKYLSTNGGIIVHHVDTTDP 165
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
K + V K VLLE+PTNPL K+VDIP+I ++P V VDNTMMS L
Sbjct: 166 AKVREVLSP--KTTMVLLETPTNPLIKIVDIPQIAAAAHEVNPACLVAVDNTMMSPLL-- 221
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
L G D+VYES TKYL+GHHDLM GVI + KLYF IN++G GLSP DSWLL
Sbjct: 222 LSPLELGADIVYESGTKYLSGHHDLMAGVIAVNDLALGEKLYFPINASGCGLSPFDSWLL 281
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
+RG+KTL VR+ QQQ NA +A +LE S GF K R+ GLRS+P + LH S
Sbjct: 282 MRGVKTLKVRMDQQQTNAQRIAEFLE-SLGF---------KVRYPGLRSHPQYDLHHSMA 331
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
G GAVLSFETG S+R+V S KL WA++VSFGCVNSL+SMPC+MSHASID + R E
Sbjct: 332 RGAGAVLSFETGDVGISERIVESAKL--WAISVSFGCVNSLISMPCRMSHASIDAKTRAE 389
Query: 377 RDFPEDLVRLCCGIENIVDLKKDLLAAM 404
R PEDL+RLC GIE+ DL DL A+
Sbjct: 390 RALPEDLIRLCVGIEDADDLIDDLRRAV 417
>gb|AAB03241.1| cystathionine beta-lyase [Emericella nidulans]
Length = 439
Score = 347 bits (891), Expect = 8e-94, Method: Composition-based stats.
Identities = 196/384 (51%), Positives = 247/384 (64%), Gaps = 27/384 (7%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
NDQ++AS P+Y S TFK ++E YDY+RSGNPTR+ L+ + K+ + + L V
Sbjct: 48 NDQYNASSVPIYQSATFKQS-SHEGGGEYDYTRSGNPTRTHLERHLAKI--MSTQRALVV 104
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
SSGM ALDVI R LL D ++ GDDLYGGT RLL + + HVDT++
Sbjct: 105 SSGMAALDVITR---LLRPGDE----VVTGDDLYGGTNRLLKYLSTNGGIIVHHVDTTNP 157
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
+K K V DK VLLE+PTNPL K+VDIP I +P+ V+VDNTMMS L
Sbjct: 158 DKVKEVLT--DKTAMVLLETPTNPLIKIVDIPTIAAASHEANPNCLVIVDNTMMSPLL-- 213
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
L G DVVYES TKYL+GHHD+M GVI P + +LYF IN++G GLSP DSWLL
Sbjct: 214 LSPLELGADVVYESGTKYLSGHHDVMAGVIAVNDPALGERLYFPINASGCGLSPFDSWLL 273
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
+RG+KTL VR+ QQQ NA +A +LE S GF K R+ GLRS+P ++LH S
Sbjct: 274 MRGVKTLKVRMDQQQANAQRIAEFLE-SHGF---------KVRYPGLRSHPQYELHHSMA 323
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
G GAVLSFETG S+R+V++ + FGCVN+L+S+PC+MSHASID E RKE
Sbjct: 324 RGAGAVLSFETGDVSVSERIVANASV---GYQRYFGCVNTLISLPCRMSHASIDAETRKE 380
Query: 377 RDFPEDLVRLCCGIENIVDLKKDL 400
R PEDL+RLC GIE++ DL DL
Sbjct: 381 RAMPEDLIRLCVGIEDVDDLIDDL 404
>ref|XP_761643.1| hypothetical protein UM05496.1 [Ustilago maydis 521]
gb|EAK86429.1| hypothetical protein UM05496.1 [Ustilago maydis 521]
Length = 953
Score = 339 bits (870), Expect = 2e-91, Method: Composition-based stats.
Identities = 193/416 (46%), Positives = 254/416 (61%), Gaps = 36/416 (8%)
Query: 11 VNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQ 70
V+ + DQ+ +S P+Y+S TFK E +DYSRSGNPTRS+LQH + +L
Sbjct: 76 VDDPNHKDQYGSSSAPIYMSATFKGLPGGE----FDYSRSGNPTRSMLQHHLCQLQNCKY 131
Query: 71 ENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVH 130
AVSSGM LDVI R ++ G IIAGDDLYGG+ RLL + + S H
Sbjct: 132 S--YAVSSGMACLDVITR--IVKTGE-----RIIAGDDLYGGSNRLLGYLASHQNIHSDH 182
Query: 131 VDTSDFEKFKTVFQSLD---------KVDCVLLESPTNPLCKVVDIPRILRFVKCISPDT 181
VDT+D K + + Q KV VLLE+PTNP K+ D+ R K +PD
Sbjct: 183 VDTTDASKVEEMLQKRSQEAAAGLCGKVSMVLLETPTNPCLKICDLQRCAAAAKKWAPDA 242
Query: 182 TVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVI 241
VVVDNTMMS PL+L G D+VY+S TKYL+GHHDLM GVI ++ ++ F I
Sbjct: 243 VVVVDNTMMSPYLMRPLEL--GVDIVYDSGTKYLSGHHDLMAGVIACDRDDLGKQIAFTI 300
Query: 242 NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFV 301
NS G L+PMDS+LL+RG+KTL VR+ +QQ +A+ +AH+L+ S GF K +
Sbjct: 301 NSIGNALTPMDSFLLLRGIKTLAVRMDRQQASAITVAHYLD-SLGF---------KVNYP 350
Query: 302 GLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
GL S+P +H GPG+VLSF TG S+R+V + +L W ++VSFGCVNSL+SMP
Sbjct: 351 GLASHPSKAVHDKQAAGPGSVLSFVTGDKALSERIVGATRL--WGISVSFGCVNSLISMP 408
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGK 417
C MSHASIDP++R R PEDL+RLC GIE+ DL DL A++ A I + + +
Sbjct: 409 CLMSHASIDPKVRAARGMPEDLIRLCVGIEDERDLLDDLENALLQAGAIRRKPSAR 464
>ref|XP_001836355.1| hypothetical protein CC1G_06440 [Coprinopsis cinerea okayama7#130]
gb|EAU85539.1| hypothetical protein CC1G_06440 [Coprinopsis cinerea okayama7#130]
Length = 914
Score = 335 bits (859), Expect = 5e-90, Method: Composition-based stats.
Identities = 191/402 (47%), Positives = 250/402 (62%), Gaps = 29/402 (7%)
Query: 11 VNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQ 70
V+ DQ+ +S P+Y + TFK + NE YDY+RSGNPTRS LQH I K+
Sbjct: 40 VDNPDMKDQYGSSSVPIYQTATFK-GVGNE----YDYTRSGNPTRSHLQHHIAKISSAA- 93
Query: 71 ENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVH 130
+ VSSGM ALDVILR LL D +IAGDDLYGGT RLL + + H
Sbjct: 94 -HAFTVSSGMAALDVILR---LLKPGDE----VIAGDDLYGGTNRLLTYIRSHLGVTVHH 145
Query: 131 VDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMM 190
VDT+D K VLLESPTNPL K+ D+ I + VK +P+ +VVDNTMM
Sbjct: 146 VDTTDPTSLHKYIHP-TKTGMVLLESPTNPLLKIADLATISKDVKERAPNAIIVVDNTMM 204
Query: 191 SGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSP 250
+ PL+ G D+VY+SATKYL+GHHDLM GV+ +IA +L F IN+ G L+P
Sbjct: 205 TSYLQRPLE--HGADIVYDSATKYLSGHHDLMAGVVTCNRDDIAQRLAFTINAVGNALTP 262
Query: 251 MDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFK 310
+DS++L+RG+KTL +R+ +QQ A ++A +L N GF + GL S+P
Sbjct: 263 IDSFMLLRGIKTLAIRMDRQQTTAQLVAEYLYN-LGF---------TVHYPGLPSHPGRD 312
Query: 311 LHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASID 370
+H +G GAVLSFETG+ E S+R+V++ +L W ++VSFGCVNSL+SMPC MSHASID
Sbjct: 313 VHLRIADGNGAVLSFETGNKELSERIVAATRL--WGISVSFGCVNSLISMPCVMSHASID 370
Query: 371 PELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEV 412
R R PEDL+RLC GIE+ DL DL A+++A IE+
Sbjct: 371 AATRAARGLPEDLIRLCVGIEDPHDLLDDLEHALLEAGAIEL 412
>ref|XP_567850.1| cystathionine beta-lyase [Cryptococcus neoformans var. neoformans
JEC21]
ref|XP_772807.1| hypothetical protein CNBK1800 [Cryptococcus neoformans var.
neoformans B-3501A]
gb|EAL18160.1| hypothetical protein CNBK1800 [Cryptococcus neoformans var.
neoformans B-3501A]
gb|AAW46333.1| cystathionine beta-lyase, putative [Cryptococcus neoformans var.
neoformans JEC21]
Length = 918
Score = 325 bits (833), Expect = 5e-87, Method: Composition-based stats.
Identities = 184/406 (45%), Positives = 247/406 (60%), Gaps = 29/406 (7%)
Query: 5 RLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGK 64
R T+ N + DQ+ AS P+Y + TFK D Q YDY+RSGNPTR L++ + +
Sbjct: 36 RFSTICANVDGK-DQYGASSTPIYQTATFK----GMDGQ-YDYTRSGNPTRGALENHLAR 89
Query: 65 LYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQS 124
LY Q A+S+GMT LD ILR LV T++AGDDLYGGT RLL +
Sbjct: 90 LYGATQ--TFALSTGMTCLDTILR-LV------RPGETVLAGDDLYGGTNRLLTYLGTHG 140
Query: 125 HAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVV 184
HVDT+D +K + V VLLESPTNPL K+ D+ I V +P +V
Sbjct: 141 GVDVRHVDTTDVDKVIPHLGPGNNVKMVLLESPTNPLLKIADLQEIADAVHSAAPSALIV 200
Query: 185 VDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINST 244
VDNTMMS PL++ G D+VY+SATKYL+GHHDLM G+I + P+I + F+INS
Sbjct: 201 VDNTMMSPYLQRPLEI--GADIVYDSATKYLSGHHDLMAGIIAASRPDICKDIAFIINSV 258
Query: 245 GAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLR 304
G+GL+P DS+LL+RG+KT+ +R+ +Q A ++A +L+ S GF + GL+
Sbjct: 259 GSGLAPFDSFLLLRGVKTMSLRMDRQMATAHLVALYLD-SFGF---------LVHYPGLK 308
Query: 305 SNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKM 364
S+P +H +G GAVLSF TG S+R+V +L W ++VSFG VNSL+SMPC M
Sbjct: 309 SHPKRDIHYKQASGAGAVLSFVTGDKALSERIVGGTRL--WGISVSFGAVNSLISMPCLM 366
Query: 365 SHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADII 410
SHASI +R ER PE+L+RLC GIE+ DL DL +++ A I
Sbjct: 367 SHASISAAVRAERGLPENLIRLCVGIEDPRDLIDDLEHSLLQAGAI 412
>ref|XP_567851.1| cystathionine beta-lyase [Cryptococcus neoformans var. neoformans
JEC21]
ref|XP_772806.1| hypothetical protein CNBK1800 [Cryptococcus neoformans var.
neoformans B-3501A]
gb|EAL18159.1| hypothetical protein CNBK1800 [Cryptococcus neoformans var.
neoformans B-3501A]
gb|AAW46334.1| cystathionine beta-lyase, putative [Cryptococcus neoformans var.
neoformans JEC21]
Length = 900
Score = 324 bits (830), Expect = 9e-87, Method: Composition-based stats.
Identities = 184/406 (45%), Positives = 247/406 (60%), Gaps = 29/406 (7%)
Query: 5 RLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGK 64
R T+ N + DQ+ AS P+Y + TFK D Q YDY+RSGNPTR L++ + +
Sbjct: 36 RFSTICANVDGK-DQYGASSTPIYQTATFK----GMDGQ-YDYTRSGNPTRGALENHLAR 89
Query: 65 LYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQS 124
LY Q A+S+GMT LD ILR LV T++AGDDLYGGT RLL +
Sbjct: 90 LYGATQ--TFALSTGMTCLDTILR-LV------RPGETVLAGDDLYGGTNRLLTYLGTHG 140
Query: 125 HAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVV 184
HVDT+D +K + V VLLESPTNPL K+ D+ I V +P +V
Sbjct: 141 GVDVRHVDTTDVDKVIPHLGPGNNVKMVLLESPTNPLLKIADLQEIADAVHSAAPSALIV 200
Query: 185 VDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINST 244
VDNTMMS PL++ G D+VY+SATKYL+GHHDLM G+I + P+I + F+INS
Sbjct: 201 VDNTMMSPYLQRPLEI--GADIVYDSATKYLSGHHDLMAGIIAASRPDICKDIAFIINSV 258
Query: 245 GAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLR 304
G+GL+P DS+LL+RG+KT+ +R+ +Q A ++A +L+ S GF + GL+
Sbjct: 259 GSGLAPFDSFLLLRGVKTMSLRMDRQMATAHLVALYLD-SFGF---------LVHYPGLK 308
Query: 305 SNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKM 364
S+P +H +G GAVLSF TG S+R+V +L W ++VSFG VNSL+SMPC M
Sbjct: 309 SHPKRDIHYKQASGAGAVLSFVTGDKALSERIVGGTRL--WGISVSFGAVNSLISMPCLM 366
Query: 365 SHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADII 410
SHASI +R ER PE+L+RLC GIE+ DL DL +++ A I
Sbjct: 367 SHASISAAVRAERGLPENLIRLCVGIEDPRDLIDDLEHSLLQAGAI 412
>ref|XP_001730996.1| hypothetical protein MGL_1995 [Malassezia globosa CBS 7966]
gb|EDP43782.1| hypothetical protein MGL_1995 [Malassezia globosa CBS 7966]
Length = 838
Score = 323 bits (828), Expect = 2e-86, Method: Composition-based stats.
Identities = 179/384 (46%), Positives = 241/384 (62%), Gaps = 36/384 (9%)
Query: 18 DQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAVS 77
DQ+ AS PVYL+ TFK YDY+R NP+RSVL++ + KL ++ AVS
Sbjct: 24 DQYGASSTPVYLTATFK----GLPGAEYDYTRVSNPSRSVLENHLAKLEGA--KHAYAVS 77
Query: 78 SGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSD-F 136
GM LDVI+R + ++AGDDLYGG+ RLL K+Q + ++DTSD
Sbjct: 78 CGMACLDVIMRMV-------GPGERVMAGDDLYGGSNRLLELLKKQMNIQVDNIDTSDPI 130
Query: 137 EKFKTVFQSLD--------KVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNT 188
E + + Q +V VLLESPTNP+ K+ D+P +R V+ P+ VVVDNT
Sbjct: 131 EVERALSQRAKEHAEGHGARVALVLLESPTNPMIKIADLPYCVRLVRKYVPEALVVVDNT 190
Query: 189 MMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGL 248
M+S PL G D+VY+SATKYL+GHHD+M GVI ++A K++F I S G GL
Sbjct: 191 MLSPYLMRPLDF--GVDIVYDSATKYLSGHHDIMAGVIACNRDDLAEKMFFTIKSVGNGL 248
Query: 249 SPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPD 308
+P+D +LL+RG+KTL +R+ +QQ +AM +A +L+ GF K R+ GLRS P
Sbjct: 249 APLDCFLLLRGVKTLALRMDRQQSSAMQVATYLD-GLGF---------KVRYPGLRSFPG 298
Query: 309 FKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHAS 368
H GPG VLSFETG S+++V++ KL W V+VSFGCVNSL+SMPC+MSHAS
Sbjct: 299 HVAHMRQARGPGGVLSFETGCTPMSEKIVAATKL--WGVSVSFGCVNSLISMPCQMSHAS 356
Query: 369 IDPELRKERDFPEDLVRLCCGIEN 392
IDP++R ER PE+L+RLC GIE+
Sbjct: 357 IDPKVRAERGLPENLIRLCVGIED 380
>ref|NP_588197.2| cystathionine beta-lyase (predicted) [Schizosaccharomyces pombe
972h-]
emb|CAA22275.2| cystathionine beta-lyase (predicted) [Schizosaccharomyces pombe]
Length = 390
Score = 315 bits (807), Expect = 5e-84, Method: Composition-based stats.
Identities = 182/406 (44%), Positives = 259/406 (63%), Gaps = 31/406 (7%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
+DT +V+ DQ+ AS P+Y S TFK E +DY+RSGNPTRSVLQ + KL
Sbjct: 9 VDTELVHVEGNEDQYHASSVPIYQSATFKQPCL-EHMGKFDYTRSGNPTRSVLQVHLAKL 67
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
+ ++ S+GM+ALD+ILR +++H ++AG DLYGG+ RLL+F ++Q
Sbjct: 68 MKA--KHAFVTSNGMSALDMILRCC----KSNSH---VVAGHDLYGGSDRLLSFNQRQYG 118
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
+VDTSD F+ + + VL+ESPTNP + DI I++ + + D +V+
Sbjct: 119 FKVDNVDTSDLAAFEAALRP--DTNLVLIESPTNPRISICDIRAIVKITRSKAKDALLVM 176
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DNTM+S + CNPL G D+VYESATKYL+GHHDLMGGVI +K+ EIA ++F IN+ G
Sbjct: 177 DNTMLSPVLCNPLDF--GYDIVYESATKYLSGHHDLMGGVIATKSDEIAKSVFFNINAMG 234
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
A ++P + +LL+RG+KT+G+R+ + Q+NA+ +A +L+ +K + F GL
Sbjct: 235 AAMAPFECFLLLRGIKTMGLRVERAQQNAIEIAKFLK----------SKGLQVNFPGL-- 282
Query: 306 NPDFK---LHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPC 362
+PD K + SF GPGAV+S TG E SK +V++ KL + ++VSFG VNSL+SMP
Sbjct: 283 DPDAKSTAIFYSFARGPGAVMSVFTGDVEVSKTIVNTTKL--FEISVSFGAVNSLISMPA 340
Query: 363 KMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
MSHASI E+R R EDL+R+C GIEN+ DLK DL A+ A+
Sbjct: 341 YMSHASIKKEVRDARGLSEDLIRICVGIENVDDLKADLENALAQAN 386
>ref|XP_001803788.1| hypothetical protein SNOG_13581 [Phaeosphaeria nodorum SN15]
gb|EAT79028.2| hypothetical protein SNOG_13581 [Phaeosphaeria nodorum SN15]
Length = 356
Score = 284 bits (727), Expect = 1e-74, Method: Composition-based stats.
Identities = 150/279 (53%), Positives = 187/279 (67%), Gaps = 17/279 (6%)
Query: 153 LLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCNPLQLNPGCDVVYESAT 212
L +PTNPL K+ DIP I + +P V VDNTMMS + NPL L G DVVYES T
Sbjct: 93 LERTPTNPLIKICDIPSIAKIAHDANPAAIVAVDNTMMSPMLLNPLDL--GADVVYESGT 150
Query: 213 KYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQR 272
KYL+GHHDLM GVI + +LYF IN++G GLSP DSWLL+RG+KTLGVR+ +QQ
Sbjct: 151 KYLSGHHDLMAGVIAINNSALGDRLYFTINASGCGLSPFDSWLLLRGIKTLGVRMEKQQD 210
Query: 273 NAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFNNGPGAVLSFETGSFEH 332
NAM +A +LE S GF K R+ GL+S+P + LH S G GAVLSFETG
Sbjct: 211 NAMRIAEFLE-SHGF---------KVRYPGLKSHPQYALHWSMARGAGAVLSFETGDVLV 260
Query: 333 SKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIEN 392
S+R+V S KL WA++VSFGCVNSL+SMPC+MSHASID + RKER+ PED+VRLC GIE+
Sbjct: 261 SERIVESAKL--WAISVSFGCVNSLISMPCRMSHASIDEKTRKERNMPEDIVRLCVGIED 318
Query: 393 IVDLKKDLLAAMVDADIIEVRENGKYLFNKLNKNLAVNT 431
DL DL A+V A + + +G F + + AV +
Sbjct: 319 PEDLIDDLSRALVQAGAVSISPDG---FRAVGADTAVTS 354
Score = 45.1 bits (105), Expect = 0.013, Method: Composition-based stats.
Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 11/92 (11%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQN----YDYSRSGNPTRSVLQ----HQIGKLYRV 68
NDQ++AS P+Y S TFK + + YDY+RSGNPTR+ L+ + + K+ +
Sbjct: 48 NDQYNASSVPIYQSATFKQESAGGSGEYVKSIYDYTRSGNPTRTHLERTPTNPLIKICDI 107
Query: 69 PQENVLAVS---SGMTALDVILRGLVLLNGTD 97
P +A + + A+D + +LLN D
Sbjct: 108 PSIAKIAHDANPAAIVAVDNTMMSPMLLNPLD 139
>emb|CAO63063.1| unnamed protein product [Vitis vinifera]
Length = 403
Score = 264 bits (675), Expect = 9e-69, Method: Composition-based stats.
Identities = 156/399 (39%), Positives = 234/399 (58%), Gaps = 26/399 (6%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
+ T+++N +++D A PP+Y + TFK E+ YDY+RSGNPTR VL+ + +L
Sbjct: 26 ISTMLINYENKSDPFDAVSPPLYQTATFKQPSATENGP-YDYTRSGNPTRDVLESLLARL 84
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
+ + +SGM AL + ++ G + I+AG+D+YGG+ RLL+ +
Sbjct: 85 DKA--DRAFCFTSGMAALAAVTH--LIAPGEE-----IVAGEDIYGGSDRLLSQVTTKRG 135
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
V VDT++ E+ + + K+ V LESPTNP ++ DI +I + ++V
Sbjct: 136 IVVKRVDTTNLEEVASAIGPMTKL--VWLESPTNPRLQISDIRKITEMAH--THGALLLV 191
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DN++MS + PL+L G D+V SATK++ GH D+M GV+ K +A LYF+ N+ G
Sbjct: 192 DNSIMSPVLSQPLEL--GADIVMHSATKFIAGHSDVMAGVLAVKGESLAKDLYFLQNAEG 249
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
+GL+P D W+ +RG+KT+ +R+ +QQ NA +A +L + + K + GL
Sbjct: 250 SGLAPFDCWICLRGIKTMALRVEKQQENAQKIAEFLSSH--------PRVKKVNYAGLPD 301
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P LH S G G+VLSF TGS E SK +V + K +++TVSFG V SL+SMPC MS
Sbjct: 302 HPGRSLHYSQAKGAGSVLSFLTGSLEFSKYIVETTKY--FSITVSFGSVKSLISMPCFMS 359
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
HASI +R+ R EDLVR+ GIE+I DL DL A+
Sbjct: 360 HASIPAAVREARGLTEDLVRISVGIEDINDLIADLDYAL 398
>gb|AAF74980.1|AF082890_1 cystathionine beta-lyase [Solanum tuberosum]
Length = 471
Score = 263 bits (671), Expect = 3e-68, Method: Composition-based stats.
Identities = 155/399 (38%), Positives = 238/399 (59%), Gaps = 26/399 (6%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
+ T+++N + D + A P+Y ++TFK E+ Q YDY+RSGNPTR L+ + +L
Sbjct: 94 VSTMLMNFSNDFDPYGALSTPLYQTSTFKQPSATENGQ-YDYTRSGNPTRDALEKLLAEL 152
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
+ + +SGM AL + R L+ + I+AGDD+YGG+ RLL+ ++
Sbjct: 153 EKA--DRAFCFTSGMAALAAVTR---LVKAGEE----IVAGDDIYGGSDRLLSQVVPKAG 203
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
V VDT++ ++ +V + K+ + LESPTNP ++ DI +I + + V+V
Sbjct: 204 IVVKRVDTTNLDEVASVIKPWTKL--IWLESPTNPRQQICDIRKIAKIAH--AHGALVLV 259
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DN++MS + +PL+L G D+V SATK+++GH DLM GV+ + +A ++YF+ N+ G
Sbjct: 260 DNSIMSPVLSHPLEL--GADIVMHSATKFISGHSDLMAGVLAVRGESLAKEVYFLQNAEG 317
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
AGL+P D WL +RG+KT+ +R+ +QQ NA +A +L + + K + GL
Sbjct: 318 AGLAPFDCWLCLRGIKTMALRVEKQQENAQKIAEFLSSH--------PRVKKVNYPGLLD 369
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P LH S G G+VLSF TGS SK + + K +++TVSFG V SL+S+PC MS
Sbjct: 370 HPGRSLHFSQATGAGSVLSFLTGSLALSKHVAEATKY--FSITVSFGSVKSLISLPCFMS 427
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
HASI E+R+ R EDLVR+ GIE++ DL DL A+
Sbjct: 428 HASIPVEVREARGLTEDLVRISVGIEDVNDLIDDLDYAL 466
>emb|CAL55420.1| putative cystathionine beta-lyase precursor CBL (ISS) [Ostreococcus
tauri]
Length = 433
Score = 260 bits (664), Expect = 2e-67, Method: Composition-based stats.
Identities = 157/395 (39%), Positives = 218/395 (55%), Gaps = 25/395 (6%)
Query: 15 SQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVL 74
S D ++AS PP+Y + TF N + YDY+RSGNPTR+ L+ Q+ Y +
Sbjct: 59 SVRDPYAASSPPLYQTATF-AQPNATENGPYDYTRSGNPTRTQLEEQMA--YLEDADRAF 115
Query: 75 AVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTS 134
A SSGM+AL + R L+N + I+ GDD+YGGT RLL + V+VD
Sbjct: 116 AFSSGMSALTCVTR---LVNAGER----IVTGDDIYGGTSRLLAQVVPKVGIEVVNVDMK 168
Query: 135 DFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLN 194
D + + K V++ESPTNP +V+DI I V VDN++M
Sbjct: 169 DLDAVRAAIAG-GKTTMVMMESPTNPRLQVIDIKAICDMAH--DKGALVCVDNSIMCPTF 225
Query: 195 CNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSW 254
+PL L G D+ SATK++ GH D+ GG++ K E+ ++YF N+ G L+P D W
Sbjct: 226 QSPLAL--GADISMTSATKFIAGHSDVTGGLLAVKGEEVGKRIYFHQNAEGLHLAPFDCW 283
Query: 255 LLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKS 314
L +RGLKT+ +R+ +QQ NAM LA WLE+ + + GL++N LH
Sbjct: 284 LALRGLKTMQLRMERQQANAMKLAKWLESH--------PRVQNVNYPGLKNNVGHDLHFR 335
Query: 315 FNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELR 374
+G G++ SF TG E SK +V KL +TVSFG SL+S+PC MSHASI E+R
Sbjct: 336 QASGAGSIFSFTTGDVEFSKIVVEETKLH--KITVSFGGTTSLISLPCFMSHASIPAEVR 393
Query: 375 KERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADI 409
R P+DLVR+ CGIE+ DL DL A A++
Sbjct: 394 AARGLPDDLVRISCGIEDGDDLLADLQYAFAVAEV 428
>ref|XP_001419577.1| cystathione beta lyase [Ostreococcus lucimarinus CCE9901]
gb|ABO97870.1| cystathione beta lyase [Ostreococcus lucimarinus CCE9901]
Length = 404
Score = 258 bits (659), Expect = 6e-67, Method: Composition-based stats.
Identities = 158/394 (40%), Positives = 217/394 (55%), Gaps = 25/394 (6%)
Query: 15 SQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVL 74
S D + AS PP+Y + TF E+ YDY+RSGNPTR+ L+ Q+ L +
Sbjct: 30 SVTDPYGASAPPLYQTATFAQPSATENGP-YDYTRSGNPTRTQLEEQMANLECA--DRAF 86
Query: 75 AVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTS 134
A SSGM+AL + R L+N + I+ GDD+YGGT RLL + V+VD +
Sbjct: 87 AFSSGMSALMCVTR---LVNAGER----IVTGDDIYGGTSRLLAQVVPKVGIEVVNVDMN 139
Query: 135 DFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLN 194
D + + Q V++ESPTNP +V+DI I V VDN++M
Sbjct: 140 DHDAVRAAIQG-GNTTMVMMESPTNPRLQVIDIKAICDMAH--EKGALVCVDNSIMCPTF 196
Query: 195 CNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSW 254
PL L G D+ SATK++ GH D+ GG++ E+ +++YF N+ G L P D W
Sbjct: 197 QAPLAL--GADISMTSATKFIAGHSDVTGGLLACNGEELGNRIYFHQNAEGLHLGPFDCW 254
Query: 255 LLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKS 314
L +RGLKT+ +R+ +QQ NAM L WLE+ R NK + GL++N +LH
Sbjct: 255 LALRGLKTMQLRMERQQENAMKLTAWLESH-----PRVNKVN---YPGLKANVGHELHSK 306
Query: 315 FNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELR 374
+G G++ SF TG E SK +V KL +TVSFG SL+S+PC MSHASI E+R
Sbjct: 307 QASGAGSIFSFTTGDVEFSKIVVEETKLH--KITVSFGGTTSLISLPCFMSHASIPAEVR 364
Query: 375 KERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
R P+DLVR+ CGIE+ DL DL A A+
Sbjct: 365 AARGLPDDLVRISCGIEDADDLLADLQYAFAVAE 398
>ref|YP_591057.1| cystathionine beta-lyase [Acidobacteria bacterium Ellin345]
gb|ABF40983.1| cystathionine beta-lyase [Acidobacteria bacterium Ellin345]
Length = 389
Score = 253 bits (646), Expect = 2e-65, Method: Composition-based stats.
Identities = 154/387 (39%), Positives = 225/387 (58%), Gaps = 26/387 (6%)
Query: 18 DQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAVS 77
D++ P+Y + TF+ + +E + YDYSRSGNPTR+VL+ + L + S
Sbjct: 16 DRYRPIATPIYQTATFEQEHADEFGE-YDYSRSGNPTRTVLEKHLASLENGTRG--FCFS 72
Query: 78 SGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFE 137
SGM A+ + +L +G D I+A DLYGGT RL +++ + + D ++ E
Sbjct: 73 SGMAAITTTTK--LLRSGDD-----ILADSDLYGGTCRLFTKVLEKTGISARYADAANLE 125
Query: 138 KFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCNP 197
+F + K+ V +E+PTNPL +V+D+ ++ + + VDN+ MS NP
Sbjct: 126 QFAQQIRPETKL--VYVETPTNPLLRVLDLRKLAEIAH--ANGAILCVDNSTMSPYLQNP 181
Query: 198 LQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLLV 257
L L G D+V SATKYL GHHD+ G I+ K E+A ++YF+ N+ G GLSP D +LL+
Sbjct: 182 LDL--GADIVLHSATKYLGGHHDVTAGAIVVKDEELAKQVYFIQNAEGNGLSPFDCFLLL 239
Query: 258 RGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFNN 317
RG+KTL +R+ QQRNA+ +A +L + K K + GL +P ++L +S
Sbjct: 240 RGIKTLKLRVDCQQRNALTIAKFLASHPDVK--------KVYYPGLADHPGYELQRSQAR 291
Query: 318 GPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKER 377
G G VLSF TGS E SK + KL + +TVSFG VNS +S+P MSHAS+ P++ +R
Sbjct: 292 GSGGVLSFTTGSVEVSKTVAELTKL--FRITVSFGSVNSSISLPGNMSHASVPPQVLAQR 349
Query: 378 DFPEDLVRLCCGIENIVDLKKDLLAAM 404
D P DLVR+ GIE+ DL DL A+
Sbjct: 350 DLPADLVRISVGIEDEEDLIADLDQAL 376
>ref|NP_850712.1| CBL (CYSTATHIONINE BETA-LYASE) [Arabidopsis thaliana]
gb|AAL36374.1| putative cystathionine beta-lyase precursor CBL [Arabidopsis
thaliana]
gb|AAM45099.1| putative cystathionine beta-lyase precursor CBL [Arabidopsis
thaliana]
Length = 449
Score = 253 bits (646), Expect = 2e-65, Method: Composition-based stats.
Identities = 156/395 (39%), Positives = 228/395 (57%), Gaps = 26/395 (6%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
+ T++VN ++ D A P+Y + TFK E+ YDY+RSGNPTR L+ + KL
Sbjct: 72 VSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGP-YDYTRSGNPTRDALESLLAKL 130
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
+ + +SGM AL + ++ NG + I+AGDD+YGG+ RLL+ +S
Sbjct: 131 DKA--DRAFCFTSGMAALSAVTH--LIKNGEE-----IVAGDDVYGGSDRLLSQVVPRSG 181
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
V V+T+ ++ K+ V LESPTNP ++ DI +I + V+V
Sbjct: 182 VVVKRVNTTKLDEVAAAIGPQTKL--VWLESPTNPRQQISDIRKISEMAH--AQGALVLV 237
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DN++MS + PL+L G D+V SATK++ GH D+M GV+ K ++A ++YF+ NS G
Sbjct: 238 DNSIMSPVLSRPLEL--GADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEG 295
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
+GL+P D WL +RG+KT+ +R+ +QQ NA +A +L + + K + GL
Sbjct: 296 SGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSH--------PRVKKVYYAGLPD 347
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P LH S G G+V SF TGS SK LV + K +++ VSFG V SL+SMPC MS
Sbjct: 348 HPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKY--FSIAVSFGSVKSLISMPCFMS 405
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDL 400
HASI E+R+ R EDLVR+ GIE++ DL DL
Sbjct: 406 HASIPAEVREARGLTEDLVRISAGIEDVDDLISDL 440
>ref|NP_191264.1| CBL (CYSTATHIONINE BETA-LYASE) [Arabidopsis thaliana]
sp|P53780|METC_ARATH Cystathionine beta-lyase, chloroplast precursor (CBL)
(Beta-cystathionase) (Cysteine lyase)
pdb|1IBJ|A Chain A, Crystal Structure Of Cystathionine Beta-Lyase From
Arabidopsis Thaliana
pdb|1IBJ|C Chain C, Crystal Structure Of Cystathionine Beta-Lyase From
Arabidopsis Thaliana
gb|AAA99176.1| cystathionine beta-lyase
emb|CAB72175.1| CYSTATHIONINE BETA-LYASE PRECURSOR (CBL) [Arabidopsis thaliana]
Length = 464
Score = 252 bits (643), Expect = 6e-65, Method: Composition-based stats.
Identities = 156/395 (39%), Positives = 228/395 (57%), Gaps = 26/395 (6%)
Query: 6 LDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKL 65
+ T++VN ++ D A P+Y + TFK E+ YDY+RSGNPTR L+ + KL
Sbjct: 87 VSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGP-YDYTRSGNPTRDALESLLAKL 145
Query: 66 YRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSH 125
+ + +SGM AL + ++ NG + I+AGDD+YGG+ RLL+ +S
Sbjct: 146 DKA--DRAFCFTSGMAALSAVTH--LIKNGEE-----IVAGDDVYGGSDRLLSQVVPRSG 196
Query: 126 AVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVV 185
V V+T+ ++ K+ V LESPTNP ++ DI +I + V+V
Sbjct: 197 VVVKRVNTTKLDEVAAAIGPQTKL--VWLESPTNPRQQISDIRKISEMAH--AQGALVLV 252
Query: 186 DNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTG 245
DN++MS + PL+L G D+V SATK++ GH D+M GV+ K ++A ++YF+ NS G
Sbjct: 253 DNSIMSPVLSRPLEL--GADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEG 310
Query: 246 AGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRS 305
+GL+P D WL +RG+KT+ +R+ +QQ NA +A +L + + K + GL
Sbjct: 311 SGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSH--------PRVKKVYYAGLPD 362
Query: 306 NPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMS 365
+P LH S G G+V SF TGS SK LV + K +++ VSFG V SL+SMPC MS
Sbjct: 363 HPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKY--FSIAVSFGSVKSLISMPCFMS 420
Query: 366 HASIDPELRKERDFPEDLVRLCCGIENIVDLKKDL 400
HASI E+R+ R EDLVR+ GIE++ DL DL
Sbjct: 421 HASIPAEVREARGLTEDLVRISAGIEDVDDLISDL 455
>gb|ACO67451.1| cystathionine beta-lyase [Micromonas sp. RCC299]
Length = 434
Score = 251 bits (641), Expect = 9e-65, Method: Composition-based stats.
Identities = 150/384 (39%), Positives = 216/384 (56%), Gaps = 25/384 (6%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
+D ++ PP+Y + TF E+ YDY+RSGNPTR +L+ ++ L + A
Sbjct: 13 HDPFDSTNPPLYQTATFGQPSATENGP-YDYTRSGNPTRDLLEKEMAALEGA--DRAFAF 69
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
SSGM+AL + R ++ G I+ GDD+YGGT RLL + V+VD +D
Sbjct: 70 SSGMSALMCVTR--LVKTGE-----RIVTGDDIYGGTSRLLAQVVPKVGIEVVNVDMNDL 122
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
+ + +S V+LESPTNP ++ DI RI + V VDN+MM+ +
Sbjct: 123 DAVRRAIES-GPTTMVMLESPTNPRLQITDIRRISEMAH--AKGALVCVDNSMMAPVFAK 179
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
PL+L G D+ SATK+++G D+ GG++ K ++ +YF N+ G L P D WL
Sbjct: 180 PLEL--GADISMTSATKFISGQSDITGGILAVKGEQLGKDIYFHQNAEGLHLGPFDCWLA 237
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
+RG+KT+ +R+ +QQ NAM +A WLE T + GL SN LHKS
Sbjct: 238 LRGIKTMALRMERQQENAMKMARWLEAHPA--------VTYVNYPGLESNKGHGLHKSQA 289
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
+G G++LSF TG SK +V +K ++ +TVSFG +SL+S+PC MSHASI E+R
Sbjct: 290 SGTGSILSFATGDVNLSKIVV--EKTELFKITVSFGNTSSLISLPCFMSHASIPAEVRAA 347
Query: 377 RDFPEDLVRLCCGIENIVDLKKDL 400
R P+DLVR+ GIE+ DL DL
Sbjct: 348 RGLPDDLVRISAGIEDADDLIADL 371
>gb|EEH58351.1| predicted protein [Micromonas pusilla CCMP1545]
Length = 378
Score = 249 bits (636), Expect = 3e-64, Method: Composition-based stats.
Identities = 156/385 (40%), Positives = 214/385 (55%), Gaps = 29/385 (7%)
Query: 18 DQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAVS 77
D AS PP+Y + TF + YDY+RSGNPTR +L+ Q+ +L + A S
Sbjct: 20 DPFMASAPPLYQTATFAQPSATTNGP-YDYTRSGNPTRDLLEMQMAELEGA--DRAFAFS 76
Query: 78 SGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDFE 137
SGM+AL + R L+ + I+ GDD+YGGT RLL Q V + V D
Sbjct: 77 SGMSALMTVTR---LVKSGER----IVTGDDIYGGTSRLL---AQVVPKVGIEVVNVDMN 126
Query: 138 KFKTVFQSLD--KVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNC 195
V++++D V+LESPTNP ++ DI I V VDN++M+ +
Sbjct: 127 DLDAVYRAVDGGNTTMVMLESPTNPRLQITDIRAISDHAH--ERGALVCVDNSIMAPVFQ 184
Query: 196 NPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWL 255
+PL L G D+ SATK++ GH D+ GG++ K +A ++YF N+ G L P D WL
Sbjct: 185 SPLAL--GADISMTSATKFIAGHSDVTGGILAVKGEALAKEVYFHQNAEGTLLGPFDCWL 242
Query: 256 LVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSF 315
+RGLKT+ +R+ +QQ NA+ +A WLE+ P T + GL SN LH S
Sbjct: 243 ALRGLKTMSLRMTKQQENAVAIARWLES----HPL----VTYVNYPGLESNAGHALHASQ 294
Query: 316 NNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRK 375
G G++LSF TG E SK +V KL + +TVSFG V+SL+S+PC MSHASI E R
Sbjct: 295 ARGGGSILSFATGDVELSKIIVEESKL--FKITVSFGGVSSLISLPCFMSHASIPAETRA 352
Query: 376 ERDFPEDLVRLCCGIENIVDLKKDL 400
R P+DLVR+ GIE+ DL DL
Sbjct: 353 ARGLPDDLVRISTGIEDAKDLLVDL 377
>ref|XP_001699229.1| cystathionine beta-lyase [Chlamydomonas reinhardtii]
gb|EDO98869.1| cystathionine beta-lyase [Chlamydomonas reinhardtii]
Length = 517
Score = 248 bits (632), Expect = 9e-64, Method: Composition-based stats.
Identities = 155/388 (39%), Positives = 217/388 (55%), Gaps = 25/388 (6%)
Query: 17 NDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQENVLAV 76
ND + AS+PP++ + TF + YDY+RSGNPTR+ L+ Q +L + A
Sbjct: 63 NDPYGASMPPLWQTATF-AQPSATTFGEYDYTRSGNPTRTCLEEQFAELE--GGDRAFAF 119
Query: 77 SSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSDF 136
+SGM AL + + L T H I+AG+D+YGGT RLL + +VD +D
Sbjct: 120 TSGMAALAAVCK----LVKTGEH---IVAGEDIYGGTSRLLMQVVPNAGVSVTNVDMTDL 172
Query: 137 EKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNCN 196
E + Q + VL+ESPTNP ++ DI I + T VDN++M+ +
Sbjct: 173 EAVRAAIQP-GRTKLVLVESPTNPRMQICDIAAIAAMSRAAGAVT--CVDNSIMAPVFQR 229
Query: 197 PLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWLL 256
PL L G D+ S TK++ GH D+ G++ K E+A ++YF+ N+ GAGL+P D WL
Sbjct: 230 PLDL--GADISMTSGTKFVGGHGDVTLGLLTVKGEELAKRVYFLQNAEGAGLAPFDCWLA 287
Query: 257 VRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSFN 316
+RGLKT+ +R+ + NA LA +L R K + GL S+ LH
Sbjct: 288 LRGLKTMALRMDRSADNAAALAEFL--------ARHPLVKKVNYPGLPSSDGHALHMRQA 339
Query: 317 NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRKE 376
G++LSFETGS E SK +V + +L + VTVSFG VNSL+S+PC MSHASI E+R
Sbjct: 340 TSGGSLLSFETGSVEASKIIVEATQL--YKVTVSFGNVNSLISLPCYMSHASIPAEVRAA 397
Query: 377 RDFPEDLVRLCCGIENIVDLKKDLLAAM 404
R P+DLVR+ GIE+ DL DL AM
Sbjct: 398 RGLPDDLVRISTGIEDARDLIADLDQAM 425
>ref|XP_001764951.1| predicted protein [Physcomitrella patens subsp. patens]
gb|EDQ70167.1| predicted protein [Physcomitrella patens subsp. patens]
Length = 410
Score = 248 bits (632), Expect = 1e-63, Method: Composition-based stats.
Identities = 151/392 (38%), Positives = 217/392 (55%), Gaps = 26/392 (6%)
Query: 18 DQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYRVPQ--ENVLA 75
D + A P+Y + TFK E YDY+RSGNPTR L+ Q+ + + +
Sbjct: 41 DPYGALSTPLYQTATFKQPSATEGGP-YDYTRSGNPTRDALERQVCRTLAKLEGADRAFC 99
Query: 76 VSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAVSVHVDTSD 135
S+GM AL ++R I+AGDD+YGG+ RLL+ +S + +DT +
Sbjct: 100 FSTGMAALATVMR-------LAEAGQEIVAGDDIYGGSDRLLSQVAPKSGLIVKRIDTGN 152
Query: 136 FEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDNTMMSGLNC 195
++ + K+ V LESPTNP + DI I + S V+VDN++MS +
Sbjct: 153 LDEVRAAVGPKTKI--VWLESPTNPRQMISDIREIAKIAHEYS--ALVIVDNSIMSPVLS 208
Query: 196 NPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAGLSPMDSWL 255
PL L G D+V SATK++ GH D+M GV+ K +A ++YF+ N+ G GLSP D WL
Sbjct: 209 RPLDL--GADIVMHSATKFIAGHSDVMAGVLAVKGESLAKEIYFLQNAEGTGLSPFDCWL 266
Query: 256 LVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNPDFKLHKSF 315
+RG+KT+ +R+ +QQ NA +A +L + P T+ + GL + LH S
Sbjct: 267 CLRGIKTMALRVEKQQANAQRIAEFLVD----HPL----VTRVNYAGLPKHTGRDLHYSQ 318
Query: 316 NNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHASIDPELRK 375
G G+V SF TGS SK +V KL +++TVSFG V SL+S+PC MSHASI +R+
Sbjct: 319 CKGAGSVFSFNTGSLAISKHVVEQTKL--FSITVSFGSVKSLISLPCFMSHASIPAGVRE 376
Query: 376 ERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
R EDL+R+ GIE++ DL DL A+ A
Sbjct: 377 ARGLTEDLIRISIGIEDVDDLVADLEQALTTA 408
>dbj|BAA95830.1| putative cystathionine beta-lyase [Oryza sativa Japonica Group]
Length = 383
Score = 244 bits (622), Expect = 1e-62, Method: Composition-based stats.
Identities = 149/384 (38%), Positives = 218/384 (56%), Gaps = 26/384 (6%)
Query: 8 TVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLYR 67
T++ + + D + P+Y + TFK + D YDY+RSGNPTR VLQ + KL +
Sbjct: 8 TILTSFENSFDGFGSMSTPLYQTATFK-QPSATDNGPYDYTRSGNPTRDVLQSLMAKLEK 66
Query: 68 VPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHAV 127
Q +SGM AL + +L +G + I+AG+D+YGG+ RLL+ + V
Sbjct: 67 ADQ--AFCFTSGMAALAAVTH--LLKSGQE-----IVAGEDIYGGSDRLLSQVAPRHGIV 117
Query: 128 SVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVDN 187
+DT+ + + L K+ V LESPTNP ++ DI +I V+VDN
Sbjct: 118 VKRIDTTKISEVTSAIGPLTKL--VWLESPTNPRLQITDIKKIAEIAH--YHGALVLVDN 173
Query: 188 TMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGAG 247
++MS + PL+L G D+V SATK++ GH DLM G++ K +A ++ F+ N+ G+G
Sbjct: 174 SIMSPVLSRPLEL--GADIVMHSATKFIAGHSDLMAGILAVKGESLAKEIAFLQNAEGSG 231
Query: 248 LSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSNP 307
L+P D WL +RG+KT+ +R+ +QQ NA +A +L + + K + GL +P
Sbjct: 232 LAPFDCWLCLRGIKTMALRVEKQQANAQKIAEFLASH--------PRVKKVNYAGLPDHP 283
Query: 308 DFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSHA 367
LH S G G+VLSF TGS SK +V + K + VTVSFG V SL+S+PC MSHA
Sbjct: 284 GRSLHYSQAKGAGSVLSFLTGSLALSKHVVETTKY--FNVTVSFGSVKSLISLPCFMSHA 341
Query: 368 SIDPELRKERDFPEDLVRLCCGIE 391
SI +R+ER +DLVR+ GIE
Sbjct: 342 SIPSAVREERGLTDDLVRISVGIE 365
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|NP_011331.1| Cystathionine beta-lyase, converts cystath... 672 0.0
ref|ZP_02914409.1| Cystathionine gamma-synthase [Geobacillu... 627 e-178
ref|ZP_03970235.1| cystathionine gamma-lyase [Sphingobacter... 622 e-176
ref|ZP_01062095.1| Cystathionine gamma-synthase [Flavobacte... 616 e-174
ref|YP_079997.1| cystathionine gamma-lyase YrhB [Bacillus l... 616 e-174
ref|YP_324649.1| Cys/Met metabolism pyridoxal-phosphate-dep... 616 e-174
ref|YP_001193064.1| Cystathionine gamma-lyase [Flavobacteri... 614 e-174
ref|YP_001126563.1| cystathionine beta-lyase [Geobacillus t... 613 e-174
ref|YP_148393.1| cystathionine beta-lyase [Geobacillus kaus... 612 e-173
ref|ZP_01173683.1| cystathionine beta-lyase [Bacillus sp. N... 611 e-173
ref|YP_001295285.1| Cys/Met metabolism PLP-dependent enzyme... 608 e-172
gb|AAX99219.1| cystathionine gamma-synthase [Helicobacter p... 608 e-172
ref|YP_626847.1| cystathionine gamma-synthase/cystathionine... 608 e-172
ref|ZP_02161506.1| Cys/Met metabolism PLP-dependent enzyme ... 607 e-172
ref|ZP_01733647.1| cystathionine gamma-lyase [Flavobacteria... 607 e-172
ref|NP_206906.1| cystathionine gamma-synthase/cystathionine... 607 e-172
ref|ZP_01120255.1| Cys/Met metabolism PLP-dependent enzyme ... 606 e-171
ref|YP_001487586.1| cystathionine beta-lyase [Bacillus pumi... 606 e-171
ref|YP_002774266.1| cystathionine gamma-lyase [Brevibacillu... 605 e-171
ref|YP_630264.1| Cys/Met metabolism PLP-dependent enzyme [M... 604 e-171
ref|NP_266937.1| cystathionine gamma-synthase/cystathionine... 604 e-171
ref|YP_001909598.1| cystathionine gamma-synthase/cystathion... 603 e-170
ref|YP_863450.1| Cys/Met metabolism pyridoxal-phosphate-dep... 603 e-170
ref|NP_834078.1| cystathionine beta-lyase [Bacillus cereus ... 603 e-170
ref|NP_980747.1| cystathionine beta-lyase [Bacillus cereus ... 603 e-170
ref|ZP_02578916.1| cystathionine beta-lyase [Bacillus cereu... 603 e-170
ref|ZP_02254620.1| cystathionine beta-lyase [Bacillus cereu... 602 e-170
ref|ZP_03983763.1| cystathionine gamma-synthase/cystathioni... 602 e-170
ref|YP_085695.1| cystathionine beta-lyase [Bacillus cereus ... 602 e-170
ref|NP_846819.1| cystathionine beta-lyase [Bacillus anthrac... 601 e-170
ref|YP_038423.1| cystathionine beta-lyase [Bacillus thuring... 601 e-170
ref|ZP_01719081.1| Cys/Met metabolism PLP-dependent enzyme ... 601 e-170
ref|ZP_00741024.1| Cystathionine beta-lyase / Cystathionin... 600 e-170
ref|ZP_00237381.1| trans-sulfuration enzyme family protein ... 600 e-170
gb|ABO43784.1| cystathionine beta lyase [Lactobacillus reut... 599 e-169
ref|YP_001270900.1| Cystathionine gamma-synthase [Lactobaci... 599 e-169
ref|ZP_00604875.1| Cystathionine gamma-synthase [Enterococc... 599 e-169
ref|ZP_01689814.1| cystathionine gamma-synthase (CGS) (O-su... 599 e-169
ref|ZP_01909681.1| Cystathionine gamma-synthase [Plesiocyst... 598 e-169
ref|YP_001376303.1| Cystathionine gamma-synthase [Bacillus ... 598 e-169
ref|YP_001647006.1| Cystathionine gamma-synthase [Bacillus ... 598 e-169
ref|NP_814082.1| cystathionine gamma-synthase/cystathionine... 598 e-169
ref|XP_646022.1| cystathionine gamma-lyase [Dictyostelium d... 597 e-169
ref|ZP_01105937.1| Cys/Met metabolism PLP-dependent enzyme ... 597 e-169
ref|ZP_00394699.1| COG0626: Cystathionine beta-lyases/cysta... 597 e-169
ref|ZP_01053161.1| Cystathionine gamma-synthase [Tenacibacu... 597 e-169
ref|ZP_03949411.1| cystathionine gamma-synthase/cystathioni... 596 e-168
ref|YP_808806.1| cystathionine gamma-synthase/cystathionine... 596 e-168
emb|CAC05298.1| cystathionine beta-lyase [Lactobacillus reu... 596 e-168
ref|ZP_02618072.1| cystathionine beta-lyase [Clostridium bo... 596 e-168
ref|ZP_02845106.1| Cystathionine gamma-synthase [Paenibacil... 596 e-168
ref|YP_001253267.1| cystathionine beta-lyase [Clostridium b... 595 e-168
ref|ZP_03982426.1| cystathionine gamma-synthase [Enterococc... 595 e-168
ref|ZP_01201479.1| cystathionine beta-lyase [Flavobacteria ... 595 e-168
ref|YP_001786093.1| cystathionine beta-lyase [Clostridium b... 595 e-168
ref|ZP_02187518.1| cystathionine gamma-lyase-like protein [... 595 e-168
ref|YP_001390087.1| cystathionine beta-lyase [Clostridium b... 595 e-168
ref|ZP_03899337.1| cystathionine gamma-lyase [Dyadobacter f... 595 e-168
ref|NP_390603.1| cystathionine beta-lyase [Bacillus subtili... 595 e-168
ref|ZP_01890642.1| Cys/Met metabolism PLP-dependent enzyme ... 595 e-168
ref|ZP_02185683.1| cystathionine beta-lyase [Carnobacterium... 595 e-168
ref|YP_665187.1| cystathionine gamma-synthase/cystathionine... 595 e-168
ref|NP_643909.1| cystathionine gamma-lyase-like protein [Xa... 594 e-168
sp|P0C2T9|METC_LACLC Cystathionine beta-lyase (CBL) (Beta-c... 594 e-168
emb|CAG01183.1| unnamed protein product [Tetraodon nigrovir... 594 e-168
ref|ZP_02612783.1| cystathionine beta-lyase [Clostridium bo... 593 e-168
ref|YP_331099.1| cystathionine synthase/lyase (cystathionin... 593 e-167
ref|ZP_01274696.1| Cystathionine gamma-synthase [Lactobacil... 593 e-167
ref|YP_002803098.1| cystathionine beta-lyase [Clostridium b... 592 e-167
ref|YP_001887506.1| cystathionine gamma-lyase [Clostridium ... 592 e-167
ref|YP_001780368.1| cystathionine beta-lyase [Clostridium b... 591 e-167
ref|XP_309478.3| AGAP011172-PA [Anopheles gambiae str. PEST... 591 e-167
ref|ZP_02181558.1| Cystathionine gamma-synthase [Flavobacte... 591 e-167
ref|ZP_02994313.1| hypothetical protein CLOSPO_01432 [Clost... 591 e-167
ref|ZP_01945763.1| putative O-succinylhomoserine (thiol)-ly... 591 e-167
ref|XP_001648394.1| cystathionine beta-lyase [Aedes aegypti... 591 e-167
gb|AAW71993.1| cystathionine gamma-lyase [Macaca fascicularis] 591 e-167
ref|ZP_01859151.1| cystathionine beta-lyase [Bacillus sp. S... 591 e-167
sp|Q60HG7|CGL_MACFA Cystathionine gamma-lyase (Gamma-cystat... 590 e-167
ref|YP_001381008.1| Cystathionine gamma-lyase [Anaeromyxoba... 590 e-167
ref|ZP_03959522.1| cystathionine gamma-lyase [Lactobacillus... 590 e-167
ref|ZP_01049833.1| Cystathionine gamma-synthase [Cellulopha... 590 e-167
ref|NP_997769.2| cystathionase (cystathionine gamma-lyase) ... 590 e-167
ref|NP_001118157.1| cystathionine gamma-lyase inhibitor [On... 590 e-167
gb|AAH67624.1| Cth protein [Danio rerio] 590 e-166
ref|YP_199417.1| cystathionine gamma-lyase-like protein [Xa... 589 e-166
ref|NP_222819.1| cystathionine beta-lyase [Helicobacter pyl... 589 e-166
ref|NP_001087988.1| hypothetical protein LOC494673 [Xenopus... 589 e-166
ref|YP_126280.1| hypothetical protein lpl0921 [Legionella p... 589 e-166
ref|NP_820998.1| cystathionine beta-lyase [Coxiella burneti... 588 e-166
gb|AAC45329.2| cystathionine gamma-lyase-like protein [Lact... 588 e-166
ref|YP_001394392.1| MetB1 [Clostridium kluyveri DSM 555] >g... 588 e-166
ref|ZP_03851922.1| cystathionine beta-lyase [Chryseobacteri... 588 e-166
ref|XP_537115.2| PREDICTED: similar to cystathionase isofor... 588 e-166
ref|XP_001844736.1| cystathionine beta-lyase [Culex pipiens... 587 e-166
ref|YP_001425430.1| putative O-succinylhomoserine (thiol)-l... 587 e-166
ref|YP_001595952.1| putative O-succinylhomoserine (thiol)-l... 587 e-166
ref|ZP_01119325.1| Cystathionine gamma-synthase [Polaribact... 586 e-165
ref|NP_989037.1| hypothetical protein LOC394634 [Xenopus tr... 586 e-165
ref|YP_001345895.1| probable cystathionine gamma-lyase [Pse... 586 e-165
ref|ZP_00972545.1| COG0626: Cystathionine beta-lyases/cysta... 585 e-165
ref|ZP_02175349.1| Cystathionine gamma-lyase [Anaeromyxobac... 585 e-165
ref|YP_001039191.1| Cystathionine gamma-synthase [Clostridi... 585 e-165
ref|YP_001814810.1| Cystathionine gamma-synthase [Exiguobac... 585 e-165
ref|YP_001477858.1| Cystathionine gamma-synthase [Serratia ... 585 e-165
dbj|BAB19922.2| cystathionine gamma-lyase [Rattus norvegicu... 585 e-165
ref|ZP_01697151.1| Cys/Met metabolism pyridoxal-phosphate-d... 585 e-165
ref|YP_466910.1| cystathionine gamma-lyase [Anaeromyxobacte... 584 e-165
ref|ZP_00949455.1| Cystathionine gamma-synthase [Croceibact... 584 e-165
ref|NP_666065.1| cystathionase [Mus musculus] >gi|27734227|... 584 e-165
ref|NP_249091.1| probable cystathionine gamma-lyase [Pseudo... 583 e-165
ref|ZP_00967105.1| COG0626: Cystathionine beta-lyases/cysta... 583 e-164
ref|XP_001634593.1| predicted protein [Nematostella vectens... 583 e-164
gb|EDL82568.1| cystathionase (cystathionine gamma-lyase) [R... 583 e-164
ref|ZP_02016714.1| Cystathionine gamma-synthase [Halorubrum... 583 e-164
ref|ZP_02325786.1| Cystathionine gamma-lyase [Anaeromyxobac... 582 e-164
ref|NP_347030.1| Cystathionine gamma-synthase [Clostridium ... 582 e-164
ref|NP_824481.1| cystathionine gamma-synthase [Streptomyces... 582 e-164
ref|YP_146720.1| cystathionine beta-lyase [Geobacillus kaus... 581 e-164
ref|YP_430828.1| Cystathionine gamma-synthase [Moorella the... 581 e-164
ref|NP_927875.1| hypothetical protein plu0523 [Photorhabdus... 580 e-164
ref|YP_001005776.1| putative cystathionine gamma-synthase [... 580 e-164
ref|XP_452961.1| unnamed protein product [Kluyveromyces lac... 580 e-163
ref|ZP_03945122.1| cystathionine gamma-synthase [Lactobacil... 580 e-163
ref|YP_001512617.1| Cystathionine gamma-synthase [Alkaliphi... 580 e-163
ref|YP_001905157.1| Cys/Met metabolism PLP-dependent enzyme... 580 e-163
ref|YP_383666.1| Cys/Met metabolism pyridoxal-phosphate-dep... 579 e-163
ref|YP_001843789.1| cystathionine beta-lyase [Lactobacillus... 579 e-163
ref|NP_970501.1| cystathionine gamma-lyase [Bdellovibrio ba... 579 e-163
ref|NP_635990.1| cystathionine gamma-lyase-like protein [Xa... 579 e-163
ref|ZP_04009503.1| cystathionine beta-lyase / cystathionine... 578 e-163
ref|ZP_03870765.1| cystathionine gamma-lyase [Halorhabdus u... 578 e-163
ref|YP_001824091.1| putative cystathionine gamma-synthase [... 578 e-163
ref|YP_348978.1| Cystathionine gamma-synthase [Pseudomonas ... 578 e-163
ref|ZP_00830322.1| COG0626: Cystathionine beta-lyases/cysta... 577 e-163
ref|YP_001422026.1| YrhB [Bacillus amyloliquefaciens FZB42]... 577 e-163
ref|YP_001558344.1| Cystathionine gamma-synthase [Clostridi... 576 e-162
ref|NP_001038050.1| cystathionase [Sus scrofa] >gi|12214372... 576 e-162
ref|NP_347566.1| Cystathionine gamma-synthase [Clostridium ... 576 e-162
ref|YP_001037978.1| Cystathionine gamma-synthase [Clostridi... 576 e-162
ref|NP_058770.1| CTL target antigen [Rattus norvegicus] >gi... 576 e-162
ref|ZP_02913262.1| Cystathionine gamma-synthase [Geobacillu... 576 e-162
ref|YP_154611.1| Cystathionine gamma-synthase [Idiomarina l... 575 e-162
ref|YP_901501.1| Cystathionine gamma-synthase [Pelobacter p... 575 e-162
ref|XP_001481546.1| cystathionine beta-lyase MetG [Aspergil... 575 e-162
ref|YP_365456.1| Cys/Met metabolism PLP-dependent enzyme [X... 574 e-162
ref|XP_001241519.1| hypothetical protein CIMG_08682 [Coccid... 574 e-162
ref|NP_951998.1| cystathionine beta-lyase [Geobacter sulfur... 574 e-162
ref|NP_001005400.1| cystathionase (cystathionine gamma-lyas... 574 e-162
gb|AAB86866.1| cystathionine gamma-lyase-like protein [Sten... 574 e-162
ref|NP_692030.1| cystathionine beta-lyase [Oceanobacillus i... 574 e-162
ref|XP_001262409.1| cystathionine beta-lyase MetG [Neosarto... 573 e-161
ref|YP_002754112.1| Cys/Met metabolism PLP-dependent enzyme... 573 e-161
gb|EEJ80111.1| cystathionine gamma-lyase [Kangiella koreens... 573 e-161
ref|NP_001040113.1| cystathionine gamma-lyase [Bombyx mori]... 572 e-161
ref|NP_611352.1| Eip55E CG5345-PA [Drosophila melanogaster]... 572 e-161
ref|ZP_03807043.1| cystathionine beta-lyase [Lactobacillus ... 572 e-161
gb|EDU44308.1| cystathionine beta-lyase [Pyrenophora tritic... 571 e-161
ref|ZP_00590711.1| Cystathionine gamma-synthase [Pelodictyo... 571 e-161
ref|YP_001307772.1| Cystathionine gamma-synthase [Clostridi... 571 e-161
ref|ZP_01853251.1| Cystathionine gamma-synthase [Planctomyc... 571 e-161
ref|YP_534933.1| Cystathionine beta-lyase / Cystathionine g... 571 e-161
ref|NP_280068.1| MetB [Halobacterium sp. NRC-1] >gi|1692359... 571 e-161
ref|ZP_03831504.1| cystathionine gamma-synthase [Pectobacte... 571 e-161
ref|XP_001589290.1| hypothetical protein SS1G_09924 [Sclero... 571 e-161
ref|ZP_02950046.1| cystathionine gamma-synthase [Clostridiu... 570 e-161
ref|NP_242494.1| cystathionine beta-lyase [Bacillus halodur... 570 e-161
ref|YP_001232580.1| Cystathionine gamma-synthase [Geobacter... 570 e-161
ref|ZP_02244687.1| cystathionine gamma-lyase-like protein [... 570 e-161
ref|YP_001578047.1| Cystathionine beta-lyase [Lactobacillus... 570 e-161
ref|ZP_03938504.1| cystathionine gamma-synthase [Lactobacil... 570 e-160
ref|ZP_03941511.1| cystathionine gamma-synthase [Lactobacil... 570 e-160
ref|YP_001543285.1| Cystathionine gamma-synthase [Herpetosi... 569 e-160
ref|NP_147803.1| cystathionine gamma-lyase [Aeropyrum perni... 569 e-160
ref|XP_001400722.1| hypothetical protein An14g00930 [Asperg... 569 e-160
ref|YP_446463.1| Cys/Met metabolism PLP-dependent enzyme su... 569 e-160
ref|ZP_01593967.1| Cystathionine gamma-synthase [Geobacter ... 569 e-160
ref|ZP_03955241.1| cystathionine gamma-lyase [Lactobacillus... 568 e-160
ref|ZP_03999690.1| cystathionine gamma-lyase [Halogeometric... 568 e-160
ref|XP_001536920.1| cystathionine beta-lyase [Ajellomyces c... 568 e-160
ref|YP_813202.1| Cystathionine beta-lyase/cystathionine gam... 568 e-160
ref|ZP_01041902.1| Cystathionine gamma-synthase [Idiomarina... 568 e-160
ref|XP_001825972.1| hypothetical protein [Aspergillus oryza... 568 e-160
ref|NP_347031.1| Cystathionine beta-lyase [Clostridium acet... 568 e-160
ref|ZP_03876613.1| cystathionine gamma-lyase [Haliangium oc... 568 e-160
gb|AAD17839.1| ecdysteroid-inducible polypeptide EIP40 [Dro... 568 e-160
ref|YP_811264.1| Cystathionine beta-lyase/cystathionine gam... 567 e-160
ref|NP_389070.1| cystathionine beta-lyase [Bacillus subtili... 566 e-160
ref|YP_549644.1| Cystathionine gamma-synthase [Polaromonas ... 566 e-160
ref|XP_001601960.1| PREDICTED: similar to cystathionine gam... 566 e-160
ref|YP_619188.1| hypothetical protein Ldb1326 [Lactobacillu... 566 e-160
ref|YP_820317.1| Cystathionine beta-lyase/cystathionine gam... 566 e-159
gb|ABL09516.1| cystathionine beta-lyase [Halobacillus halop... 566 e-159
ref|YP_139336.1| cystathionine beta-lyase [Streptococcus th... 566 e-159
ref|XP_962657.1| cystathionine beta-lyase [Neurospora crass... 566 e-159
ref|YP_001124871.1| cystathionine beta-lyase [Geobacillus t... 566 e-159
ref|YP_141252.1| cystathionine beta-lyase [Streptococcus th... 565 e-159
ref|YP_300343.1| cystathionine gamma-synthase [Staphylococc... 565 e-159
ref|ZP_01389888.1| Cystathionine gamma-synthase [Geobacter ... 564 e-159
ref|NP_951999.1| cystathionine beta-lyase [Geobacter sulfur... 564 e-159
ref|XP_001558791.1| hypothetical protein BC1G_02862 [Botryo... 564 e-159
ref|YP_001438833.1| hypothetical protein ESA_02766 [Enterob... 564 e-159
ref|YP_001321486.1| Cystathionine gamma-synthase [Alkaliphi... 564 e-159
ref|ZP_00820472.1| COG0626: Cystathionine beta-lyases/cysta... 563 e-159
ref|YP_254463.1| cystathionine gamma-synthase [Staphylococc... 563 e-159
ref|NP_765878.1| cystathionine gamma-synthase [Staphylococc... 563 e-158
ref|XP_001014936.1| Cystathionine beta-lyase [Tetrahymena t... 563 e-158
ref|ZP_00823949.1| COG0626: Cystathionine beta-lyases/cysta... 563 e-158
ref|ZP_03859526.1| cystathionine gamma-lyase [Kribbella fla... 563 e-158
ref|ZP_01988130.1| O-succinylhomoserine (thiol)-lyase [Vibr... 562 e-158
ref|YP_818758.1| Cystathionine beta-lyase/cystathionine gam... 562 e-158
ref|ZP_03913719.1| cystathionine gamma-lyase [Leuconostoc m... 562 e-158
ref|YP_697502.1| cystathionine beta-lyase [Clostridium perf... 562 e-158
ref|NP_799144.1| cystathionine gamma-synthase [Vibrio parah... 562 e-158
ref|YP_001708916.1| cystathionine gamma-synthase [Clavibact... 562 e-158
ref|ZP_01386815.1| Cystathionine gamma-synthase [Chlorobium... 561 e-158
gb|AAF74980.1|AF082890_1 cystathionine beta-lyase [Solanum ... 561 e-158
ref|YP_694633.1| cystathionine beta-lyase [Clostridium perf... 561 e-158
ref|XP_719662.1| cystathionine beta-lyase [Candida albicans... 561 e-158
ref|YP_001500423.1| O-succinylhomoserine (thiol)-lyase [She... 561 e-158
ref|YP_001475773.1| Cystathionine gamma-synthase [Shewanell... 561 e-158
ref|ZP_01389889.1| Cystathionine gamma-synthase [Geobacter ... 561 e-158
ref|YP_375448.1| Cystathionine gamma-synthase [Pelodictyon ... 561 e-158
ref|YP_001616816.1| Cystathionine gamma-synthase [Sorangium... 561 e-158
ref|XP_001426097.1| hypothetical protein GSPATT00029327001 ... 561 e-158
ref|YP_001307386.1| Cystathionine gamma-synthase [Clostridi... 560 e-158
ref|NP_859593.1| cystathionine gamma-synthase [Helicobacter... 560 e-158
ref|YP_078488.1| putative Cystathionine beta-lyase [Bacillu... 560 e-158
gb|AAI51524.1| CTH protein [Bos taurus] 560 e-158
ref|ZP_00828539.1| COG0626: Cystathionine beta-lyases/cysta... 560 e-158
ref|ZP_02635841.1| cystathionine beta-lyase [Clostridium pe... 560 e-157
ref|YP_001232581.1| Cystathionine gamma-synthase [Geobacter... 560 e-157
ref|XP_422542.2| PREDICTED: similar to cystathionase [Gallu... 560 e-157
ref|YP_001103161.1| cystathionine gamma-synthase [Saccharop... 560 e-157
ref|YP_001221613.1| cystathionine gamma-synthase [Clavibact... 559 e-157
ref|YP_001759013.1| O-succinylhomoserine (thiol)-lyase [She... 559 e-157
ref|YP_001680311.1| cystathionine gamma-synthase, putative ... 559 e-157
ref|XP_001910364.1| unnamed protein product [Podospora anse... 559 e-157
gb|EEJ97771.1| cystathionine gamma-lyase [Thermomonospora c... 559 e-157
ref|YP_001251671.1| cystathionine beta-lyase [Legionella pn... 559 e-157
ref|ZP_02631667.1| cystathionine beta-lyase [Clostridium pe... 558 e-157
ref|YP_591574.1| cystathionine gamma-lyase [Acidobacteria b... 558 e-157
ref|ZP_02158428.1| cystathionine gamma-synthase [Shewanella... 558 e-157
ref|XP_001223755.1| hypothetical protein CHGG_04541 [Chaeto... 558 e-157
ref|XP_367149.1| hypothetical protein MGG_07074 [Magnaporth... 558 e-157
ref|ZP_01593966.1| Cystathionine gamma-synthase [Geobacter ... 558 e-157
ref|ZP_02638932.1| cystathionine beta-lyase [Clostridium pe... 558 e-157
ref|NP_001019738.1| cystathionase [Bos taurus] >gi|75039975... 558 e-157
ref|NP_561092.1| cystathionine gamma-synthase [Clostridium ... 558 e-157
ref|XP_513486.2| PREDICTED: cystathionase isoform 2 [Pan tr... 558 e-157
ref|YP_002773358.1| cystathionine beta-lyase [Brevibacillus... 558 e-157
ref|XP_502248.1| hypothetical protein [Yarrowia lipolytica]... 557 e-157
ref|ZP_02952627.1| cystathionine beta-lyase [Clostridium pe... 557 e-157
pdb|2NMP|A Chain A, Crystal Structure Of Human Cystathionin... 557 e-157
ref|YP_520216.1| hypothetical protein DSY3983 [Desulfitobac... 557 e-157
ref|ZP_02061867.1| cystathionine gamma-lyase (Gamma-cystath... 556 e-157
ref|XP_382108.1| hypothetical protein FG01932.1 [Gibberella... 556 e-156
gb|ABG54358.1| cystathionine-gamma-lyase [Klebsiella pneumo... 556 e-156
ref|NP_001893.2| cystathionase isoform 1 [Homo sapiens] >gi... 556 e-156
ref|ZP_01643667.1| Cystathionine gamma-synthase [Stenotroph... 556 e-156
gb|AAB24700.1| cystathionine gamma-lyase; cystathionase [Ho... 556 e-156
gb|AAP36257.1| Homo sapiens cystathionase (cystathionine ga... 556 e-156
ref|YP_415909.1| cystathionine gamma-synthase [Staphylococc... 556 e-156
ref|YP_901500.1| Cystathionine gamma-synthase [Pelobacter p... 556 e-156
ref|YP_001420789.1| YjcJ [Bacillus amyloliquefaciens FZB42]... 556 e-156
gb|AAA64984.1| unknown [Pantoea agglomerans] 556 e-156
ref|ZP_01776903.1| Cystathionine gamma-synthase [Geobacter ... 555 e-156
ref|YP_094924.1| cystathionine beta-lyase [Legionella pneum... 555 e-156
ref|NP_373671.1| cystathionine gamma-synthase [Staphylococc... 555 e-156
ref|XP_001528683.1| cystathionine beta-lyase [Lodderomyces ... 555 e-156
ref|ZP_01704739.1| O-succinylhomoserine (thiol)-lyase [Shew... 554 e-156
ref|YP_001337036.1| putative cystathionine gamma-synthase [... 554 e-156
ref|ZP_01776902.1| Cystathionine gamma-synthase [Geobacter ... 554 e-156
ref|YP_175441.1| cystathionine gamma-synthase [Bacillus cla... 554 e-156
ref|ZP_02848090.1| Cystathionine gamma-synthase [Paenibacil... 554 e-156
ref|XP_001848094.1| cystathionine gamma-lyase [Culex pipien... 554 e-156
ref|YP_001004505.1| cystathionine gamma-synthase [Yersinia ... 554 e-156
ref|ZP_02840286.1| Cystathionine gamma-synthase [Arthrobact... 554 e-156
ref|YP_001092651.1| O-succinylhomoserine (thiol)-lyase [She... 554 e-156
ref|YP_001405148.1| Cystathionine gamma-lyase [Candidatus M... 554 e-156
ref|YP_185391.1| trans-sulfuration enzyme family protein [S... 554 e-156
ref|ZP_01695913.1| Cys/Met metabolism pyridoxal-phosphate-d... 554 e-156
ref|ZP_01371261.1| Cys/Met metabolism pyridoxal-phosphate-d... 554 e-156
ref|YP_002773359.1| cystathionine gamma-synthase/O-acetylho... 553 e-156
ref|ZP_03855854.1| cystathionine beta-lyase/cystathionine g... 553 e-156
ref|ZP_01261729.1| cystathionine gamma-synthase [Vibrio alg... 553 e-156
gb|EEJ80271.1| cystathionine gamma-synthase [Kangiella kore... 553 e-156
ref|YP_964920.1| O-succinylhomoserine (thiol)-lyase [Shewan... 553 e-155
ref|ZP_00832333.1| COG0626: Cystathionine beta-lyases/cysta... 553 e-155
ref|YP_871242.1| O-succinylhomoserine (thiol)-lyase [Shewan... 553 e-155
ref|YP_001552998.1| O-succinylhomoserine (thiol)-lyase [She... 553 e-155
Sequences not found previously or not previously below threshold:
ref|ZP_01886342.1| Cys/Met metabolism PLP-dependent enzyme ... 603 e-171
ref|NP_629110.1| cystathionine gamma-synthase [Streptomyces... 575 e-162
ref|ZP_03816632.1| cystathionine gamma-lyase [Actinosynnema... 566 e-159
ref|NP_105358.1| cystathionine gamma-lyase [Mesorhizobium l... 564 e-159
ref|YP_922185.1| Cystathionine gamma-synthase [Nocardioides... 560 e-158
ref|YP_121043.1| cystathionine gamma-synthase [Nocardia far... 558 e-157
ref|YP_001360844.1| Cystathionine gamma-synthase [Kineococc... 555 e-156
ref|YP_001686522.1| Cystathionine gamma-lyase [Caulobacter ... 555 e-156
ref|YP_001133312.1| cystathionine gamma-synthase [Mycobacte... 553 e-155
>ref|NP_011331.1| Cystathionine beta-lyase, converts cystathionine into homocysteine;
Str3p [Saccharomyces cerevisiae]
sp|P53101|STR3_YEAST Cystathionine beta-lyase (CBL) (Beta-cystathionase) (Cysteine
lyase)
emb|CAA62790.1| putative cystathionine /cysteine metabolism protein [Saccharomyces
cerevisiae]
emb|CAA96896.1| unnamed protein product [Saccharomyces cerevisiae]
gb|EDN61942.1| cystathionine beta-lyase [Saccharomyces cerevisiae YJM789]
Length = 465
Score = 672 bits (1736), Expect = 0.0, Method: Composition-based stats.
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MPIKRLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
MPIKRLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH
Sbjct: 1 MPIKRLDTVVVNTGSQNDQHSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF
Sbjct: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD
Sbjct: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
Query: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV
Sbjct: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
Query: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF
Sbjct: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
Query: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
VGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM
Sbjct: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLF 420
PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLF
Sbjct: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIEVRENGKYLF 420
Query: 421 NKLNKNLAVNTTIDDLHKPLSIYEEFYNQDLIRKDSELNIKSSKL 465
NKLNKNLAVNTTIDDLHKPLSIYEEFYNQDLIRKDSELNIKSSKL
Sbjct: 421 NKLNKNLAVNTTIDDLHKPLSIYEEFYNQDLIRKDSELNIKSSKL 465
>ref|ZP_02914409.1| Cystathionine gamma-synthase [Geobacillus sp. WCH70]
gb|EDT34473.1| Cystathionine gamma-synthase [Geobacillus sp. WCH70]
Length = 378
Score = 627 bits (1617), Expect = e-178, Method: Composition-based stats.
Identities = 138/401 (34%), Positives = 218/401 (54%), Gaps = 27/401 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ G D H+ +V P+Y +T+K + + ++YSR+GNPTR L+ I
Sbjct: 2 RRKTKLIHGGISGDPHTGAVSVPIYQVSTYKQEGIGGH-KGFEYSRTGNPTRHALEELIK 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SSGM A+ ++ +L N D+ +I DD+YGGT R++ +
Sbjct: 61 DLEE--GYAGFAFSSGMAAITAVM---MLFNSGDH----VILTDDVYGGTYRVMTKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
S +DTSD + Q K + +E+PTNPL K+ DI K
Sbjct: 112 LGLESTFIDTSDLSNIEKHIQPNTK--ALYIETPTNPLLKITDIQAASAIAK--KHGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + P+ L G D+V SATKYL GH D++ G+ + + E+A KL+F+ NS
Sbjct: 168 IVDNTFSTPYWQTPIAL--GADIVVHSATKYLGGHSDVVAGLAVVNSEELAEKLHFIQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DSWLL+RG+KTLGVR+ + + N + +L N K + GL
Sbjct: 226 TGGILGPQDSWLLMRGIKTLGVRMEEHEENTRKIVEFLVNH--------PAVQKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P++++ K G G ++SF+ GS E + R+++ ++ + + S G V SL+S+P K
Sbjct: 278 ETHPNYEIAKKQMRGFGGMVSFDVGSAEKADRVLN--RVRYFTLAESLGAVESLISLPAK 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+HASI E R++ + L+R+ G+E++ DL +DL A+
Sbjct: 336 MTHASIPKERREQLGITDGLIRISVGLEDVEDLLEDLAQAL 376
>ref|ZP_03970235.1| cystathionine gamma-lyase [Sphingobacterium spiritivorum ATCC
33300]
gb|EEI90062.1| cystathionine gamma-lyase [Sphingobacterium spiritivorum ATCC
33300]
Length = 381
Score = 622 bits (1605), Expect = e-176, Method: Composition-based stats.
Identities = 128/401 (31%), Positives = 202/401 (50%), Gaps = 25/401 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T ++ G Q+D + +V P+Y ++T++ + + ++YSR NPTR L+ +
Sbjct: 4 KFATKAIHAGQQSDPTTGAVMTPIYQTSTYQQASPGDH-KGFEYSRGTNPTRKALEDCLA 62
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L ++ LA +SGM A D +LR LL D ++ GDDLYGG+ R+ +Q
Sbjct: 63 ALEN--GKHGLAFASGMAATDCVLR---LLKPGDE----VVTGDDLYGGSYRIFTKVYEQ 113
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
V+TSD E + DK + +E+PTNP K+ DI I + K +
Sbjct: 114 YGITFKFVNTSDAEAVRAAIT--DKTKLIWVETPTNPTLKLADIEAIGQIAKTG--NALY 169
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VVDNT S NPL L G D+V SATKY+NGH D++ G +I E+ +L+F N+
Sbjct: 170 VVDNTFASPYLQNPLDL--GADIVMHSATKYINGHSDVVMGALILNDDELYKQLWFYYNA 227
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G P DS+L +RG+KTL +R+ N +A +L+N K + G
Sbjct: 228 CGGTPGPQDSFLALRGIKTLHLRMEAHCANGRKVAEFLKNH--------PKVETIYWPGF 279
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+P ++ K G ++S + + S + ++ + S G V SL++ P
Sbjct: 280 EDHPGHEIAKKQMRDFGGMISIVLKGADMQETFRISSRFKVFTLAESLGGVESLINHPAT 339
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+H SI E R++ ++L+RL GIE+ DL +DL A+
Sbjct: 340 MTHGSIPKEAREKVGVVDNLLRLSVGIEDADDLIEDLKQAL 380
>ref|ZP_01062095.1| Cystathionine gamma-synthase [Flavobacterium sp. MED217]
gb|EAQ48224.1| Cystathionine gamma-synthase [Leeuwenhoekiella blandensis MED217]
Length = 380
Score = 616 bits (1589), Expect = e-174, Method: Composition-based stats.
Identities = 129/405 (31%), Positives = 201/405 (49%), Gaps = 30/405 (7%)
Query: 5 RLDTVVVNTGSQN-DQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQI 62
+ +T ++ G N D + + +PP+Y ++T+ + ++YSRSGNPTR L+ +
Sbjct: 2 KFNTKTIHGGQHNTDPAYGSVMPPIYQTSTYAQSTPGGH-KGFEYSRSGNPTRKALEDAL 60
Query: 63 GKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQ 122
L + LA SG+ A+D +L+ L D II+ +DLYGG+ RL +
Sbjct: 61 ASLEN--GQFGLAFGSGLAAIDAVLK---LFKPGDE----IISTNDLYGGSYRLFTKIFE 111
Query: 123 QSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTT 182
V D + +K + +E+PTNP+ ++DI + +
Sbjct: 112 DFGLKFHFVSMQDTSAIEAAI--NEKTKMIWVETPTNPMMNIIDIEAVAQVA--TKHKIL 167
Query: 183 VVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
+ VDNT + PL L G D+V S TKYL GH DL+ G +I K E+A KLYF+ N
Sbjct: 168 LAVDNTFATPYLQQPLDL--GADLVMHSVTKYLGGHSDLVMGGLIVKDKELADKLYFIQN 225
Query: 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVG 302
++GA P DS+L +RG+KTL VR+ + N +A +L+ K + + G
Sbjct: 226 ASGAVCGPQDSFLALRGIKTLHVRMQRHCENGKAVAQFLKEH--------PKVDEVYWPG 277
Query: 303 LRSNPDFKLHKSFNNGPGAVLSFETG--SFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
+P+ ++ K G ++SF T S E + +V KL ++ + S G V SL
Sbjct: 278 FEEHPNHEIAKKQMKDFGGMVSFTTKKDSLEGAVEVVE--KLKVFTLAESLGGVESLAGH 335
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
P M+HASI E R++ + L+RL GIE+ DL DL A+
Sbjct: 336 PASMTHASIPKEERQKTGIKDSLIRLSVGIEDADDLLADLEQALA 380
>ref|YP_079997.1| cystathionine gamma-lyase YrhB [Bacillus licheniformis ATCC 14580]
ref|YP_092416.1| cystathionine beta-lyase [Bacillus licheniformis ATCC 14580]
gb|AAU24359.1| cystathionine gamma-lyase YrhB [Bacillus licheniformis ATCC 14580]
gb|AAU41723.1| YrhB [Bacillus licheniformis DSM 13]
Length = 380
Score = 616 bits (1589), Expect = e-174, Method: Composition-based stats.
Identities = 136/402 (33%), Positives = 221/402 (54%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T +++ G D+ + +V P+Y +T+K + Y+YSR+GNPTR+ L+ I
Sbjct: 2 KPKTKMIHGGITGDEKTGAVSVPIYQVSTYKQPRAGQH-TGYEYSRTGNPTRTALESLIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ A SGM A+ ++ +L D+ I+ DD+YGGT R++ +
Sbjct: 61 DVEG--GAAGYAFGSGMAAITAVM---MLFKSGDH----IVLTDDVYGGTYRVMTKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ DTS E + + K + +E+PTNPL K+ DI + K D +
Sbjct: 112 IGIEATFSDTSSIEDIEKAIKPNTK--AIYVETPTNPLLKITDIKKTAETAK--KHDLLL 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + NP+ L G D+V SATKYL GH D++GG++++ + E+A +++F+ NS
Sbjct: 168 IVDNTFYTPYFQNPISL--GADIVLHSATKYLGGHSDVVGGLVVAASKELAEEIHFIQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DSWLL+RG+KTLG+R+ ++NA +A +L++ K + GL
Sbjct: 226 TGGILGPQDSWLLMRGMKTLGLRMEAHEQNARKIAAFLDDH--------PAVKKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+P +L K + G G ++SF+ G E+ ++ +L + + S G V SL+S+P +
Sbjct: 278 PSHPGHELAKRQSTGFGGMISFDIGKEENVDLVLG--RLKWFTIAESLGAVESLISVPAR 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI PE R E + L+R+ G+E+I DL +DL A+
Sbjct: 336 MTHASIPPERRLELGITDGLIRISAGVEDIDDLLEDLQQALA 377
>ref|YP_324649.1| Cys/Met metabolism pyridoxal-phosphate-dependent enzyme [Anabaena
variabilis ATCC 29413]
gb|ABA23754.1| cystathionine gamma-lyase [Anabaena variabilis ATCC 29413]
Length = 378
Score = 616 bits (1589), Expect = e-174, Method: Composition-based stats.
Identities = 143/401 (35%), Positives = 224/401 (55%), Gaps = 28/401 (6%)
Query: 6 LDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGK 64
+T ++ G Q+D + +V P+YL++T++ + + + Y+YSR+GNPTR+ L+ +
Sbjct: 3 FETKAIHEGQQSDPQTGAVIVPIYLTSTYQQEAIGQH-KGYEYSRTGNPTRNALEEALAA 61
Query: 65 LYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQS 124
+ E LA +SG+ A +L LL D+ I+AGDDLYGGT RLL +
Sbjct: 62 IEN--GEYGLAFASGLAATTTVLS---LLKSCDH----IVAGDDLYGGTYRLLERVVKNW 112
Query: 125 HAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVV 184
+ +VD D F Q K + +E+PTNPL K++DI + + + +V
Sbjct: 113 GVTTTYVDIDDISNFAKAIQPNTK--LIWVETPTNPLLKIIDIAALANIAE--QNNLILV 168
Query: 185 VDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINST 244
VDNT S PL G D+V S TKYL GH D++GG +++ ++ ++L F N+
Sbjct: 169 VDNTFASPYFQRPLD--NGADIVVHSTTKYLGGHSDIIGGAVVTSNEQLYTELKFYQNAI 226
Query: 245 GAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLR 304
GA SP DSWL++RG+KTL VR+ + ++NA++LA +LE K + + GL
Sbjct: 227 GAVPSPFDSWLVLRGIKTLAVRMREHEKNALLLAQFLEQH--------PKVERVYYPGLP 278
Query: 305 SNPDFKLHKSFNNGPGAVLSFET-GSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ +L KS +G G ++S E G F ++ + +L ++ + S G V SLL P K
Sbjct: 279 SHEQHQLAKSQMSGFGGMISLELKGDFADVEKF--ASRLQLFLLAESLGGVESLLCYPAK 336
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+H S+ E R +R ++LVRL GIEN++DL+ DL A+
Sbjct: 337 MTHGSLPQEERYKRGINDNLVRLSVGIENVLDLQADLENAL 377
>ref|YP_001193064.1| Cystathionine gamma-lyase [Flavobacterium johnsoniae UW101]
gb|ABQ03745.1| cystathionine gamma-lyase [Flavobacterium johnsoniae UW101]
Length = 380
Score = 614 bits (1584), Expect = e-174, Method: Composition-based stats.
Identities = 136/402 (33%), Positives = 208/402 (51%), Gaps = 24/402 (5%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T V++ G +D + +V PPVY ++TF + +Y+YSR+ NPTR+ L+ +
Sbjct: 2 KFNTKVIHGGQHHDPSTGAVMPPVYQTSTFIQTSPGKPLADYEYSRASNPTRTALEEALA 61
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ LA SSG+ A D ILR D +IA DDLYGGT R+ + +
Sbjct: 62 SIENGT--RGLAFSSGLAATDCILRS---FKAGDE----VIAMDDLYGGTYRMFSRIYKD 112
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
S VD +D K K++ + V +E+PTNPL K+ DI + + K
Sbjct: 113 SGIKFHFVDMTDLAKLKSLI--NENTKLVWVETPTNPLMKLADIAEVAKITK--EHKIWF 168
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + PL L G D+V SATKYL GH D++ G +I K + +L+F +
Sbjct: 169 AVDNTFATPYLQKPLDL--GADIVMHSATKYLGGHSDVIAGALIVKDEALGEQLHFQQFA 226
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TGA L PMDS+L++RG+KTL +R+ + N + +L ++ K + + GL
Sbjct: 227 TGATLGPMDSFLVLRGIKTLALRVQRHCENGEKVVEYL--------SKHPKINRVYYPGL 278
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P ++ K G ++SF S + + +KL ++ + S G V SL + P
Sbjct: 279 ENHPFHEIAKKQMKAFGGMVSFTFKSGKKEDSIAFLEKLKVFTLAESLGGVESLANHPAL 338
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + R E +DLVRL GIE++ DL DL A+
Sbjct: 339 MTHASIPADKRAEVGITDDLVRLSVGIEDVEDLIADLEQALA 380
>ref|YP_001126563.1| cystathionine beta-lyase [Geobacillus thermodenitrificans NG80-2]
gb|ABO67818.1| Cystathionine gamma-lyase [Geobacillus thermodenitrificans NG80-2]
Length = 377
Score = 613 bits (1583), Expect = e-174, Method: Composition-based stats.
Identities = 139/401 (34%), Positives = 226/401 (56%), Gaps = 27/401 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T++++ G D H+ +V P+Y +T+K + + + ++YSR+GNPTR+ L+ I
Sbjct: 2 RRKTLLIHGGIPGDPHTGAVSVPIYQVSTYKQEEVGKH-KGFEYSRTGNPTRAALEKLIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L E A +SGM A+ ++ +L + D+ I+ DD+YGGT R++ +
Sbjct: 61 DLEG--GEAGFAFASGMAAITAVM---MLFDSGDH----IVLTDDVYGGTYRVMANVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
S VDTSD + + K + +E+PTNPL K+ D+ + +
Sbjct: 112 FGLESTFVDTSDIANIEAHIRPNTK--AIYIETPTNPLLKITDLKA--AAAIARAHGLLL 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + PL+L G D+V SATKYL GH D++ G+ + +T E+A +L++V NS
Sbjct: 168 IVDNTFSTPYFQTPLEL--GADIVIHSATKYLGGHSDVVAGLAVVRTAELAERLHYVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DSWLL+RG+KTLGVR+ + ++NA +A +L T+ + GL
Sbjct: 226 TGGILGPQDSWLLMRGMKTLGVRMEEHEQNARAIAAFLAEHQA--------VTRVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+P+ +L K+ G G ++SF+ GS E ++ ++S ++ + + S G V SL+S+P K
Sbjct: 278 PEHPNHELAKAQMRGFGGMISFDVGSLERAETVLS--RVRYFTLAESLGAVESLISLPGK 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+HASI E R++ + L+RL G+E++ DL DL A+
Sbjct: 336 MTHASIPKERREQLGITDGLIRLSVGLEDVNDLIDDLAQAL 376
>ref|YP_148393.1| cystathionine beta-lyase [Geobacillus kaustophilus HTA426]
dbj|BAD76825.1| cystathionine gamma-synthase [Geobacillus kaustophilus HTA426]
Length = 377
Score = 612 bits (1579), Expect = e-173, Method: Composition-based stats.
Identities = 136/401 (33%), Positives = 223/401 (55%), Gaps = 27/401 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T++++ G D H+ +V P+Y +T+K + + + ++YSR+GNPTR+ L+ I
Sbjct: 2 RRKTMLIHGGIPGDPHTGAVSVPIYQVSTYKQEEVGKH-KGFEYSRTGNPTRAALEKLIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L E A +SGM A+ ++ +L D+ ++ DD+YGGT R++ +
Sbjct: 61 DLEG--GEAGFAFASGMAAITAVM---MLFQSGDH----LVLTDDVYGGTYRVMTNVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ VDTSD + + K + +E+PTNPL K+ D+ + +
Sbjct: 112 FGLEATFVDTSDVANIEAHIRPNTK--AIYIETPTNPLLKITDLQA--AAAIARAHGLLL 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + PL+L G D+V SATKYL GH D++ G+ + +TPE+A +L++V NS
Sbjct: 168 IVDNTFSTPYFQTPLEL--GADIVIHSATKYLGGHSDVVAGLAVVRTPELAERLHYVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DSWLL+RG+KTL VR+ + + NA +A +L + + GL
Sbjct: 226 TGGVLGPQDSWLLMRGMKTLAVRMEEHEENARQIAVFLAEHKA--------VKRVHYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+P+ +L K G G ++SF+ GS E +++++S ++ + + S G V SL+S+P K
Sbjct: 278 PDHPNHELAKKQMRGFGGMISFDVGSLERAEKVLS--RVRYFTLAESLGAVESLISLPGK 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+HASI E R++ + L+RL G+E++ DL DL A+
Sbjct: 336 MTHASIPKERREQLGITDGLIRLSVGLEDVNDLLDDLAKAL 376
>ref|ZP_01173683.1| cystathionine beta-lyase [Bacillus sp. NRRL B-14911]
gb|EAR63626.1| cystathionine beta-lyase [Bacillus sp. NRRL B-14911]
Length = 378
Score = 611 bits (1577), Expect = e-173, Method: Composition-based stats.
Identities = 138/403 (34%), Positives = 219/403 (54%), Gaps = 27/403 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T +++ G D H+ +V P+Y +T+K + + ++YSR+GNPTR L+ I
Sbjct: 2 KRKTKLIHGGIAGDPHTGAVNIPIYQVSTYKQEGVGGH-KGFEYSRTGNPTRHALEELIK 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L E A SGM A+ ++ +L + D+ +I DD+YGGT R+++ +
Sbjct: 61 DLEG--GEAGFAFGSGMAAITAVM---MLFDSGDH----VIMTDDVYGGTYRVMSKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
S VDTS+ + + + K V LE+PTNPL K+ DI
Sbjct: 112 FGIESSFVDTSNLDNIEAEIKPNTK--AVYLETPTNPLLKITDIEG--AAAAAKKHGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + P+ L G D+V SATKY+ GH D++ G+++ + ++A L+FV NS
Sbjct: 168 IVDNTFSTPYWQTPISL--GADIVLHSATKYIGGHSDVVAGLVVVNSSKLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DSWLL+RG+KTLGVR+ + + N + +L+N +K + G+
Sbjct: 226 TGGVLGPQDSWLLMRGIKTLGVRMEETEENTKAIVEFLQNH--------PAVSKVYYPGI 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+P+ ++ K G G ++SF+ GS E++ RL+S K+ + + S G V SL+S+P +
Sbjct: 278 ESHPNHEVAKKQAQGFGGMVSFDVGSEENADRLLS--KVKYFTLAESLGAVESLISVPAR 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI E R E + LVR+ G+E+ DL +DL A+
Sbjct: 336 MTHASIPAERRAELGITDGLVRISVGLEDSEDLIEDLKNALEK 378
>ref|YP_001295285.1| Cys/Met metabolism PLP-dependent enzyme [Flavobacterium
psychrophilum JIP02/86]
emb|CAL42467.1| Cys/Met metabolism PLP-dependent enzyme [Flavobacterium
psychrophilum JIP02/86]
Length = 382
Score = 608 bits (1570), Expect = e-172, Method: Composition-based stats.
Identities = 143/403 (35%), Positives = 211/403 (52%), Gaps = 26/403 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNED-AQNYDYSRSGNPTRSVLQHQI 62
+ +T V++ G +D + +V PPVY ++TF + +Y+YSR+ NPTRS L++ +
Sbjct: 2 KFNTKVIHGGQHHDPSTGAVMPPVYQTSTFVQTSPGQPLNPDYEYSRAANPTRSALENAL 61
Query: 63 GKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQ 122
+ LA SSG+ A D +LR D IIA DDLYGGT R+
Sbjct: 62 ASIENGT--RGLAFSSGLAATDCVLRS---FKAGDE----IIAMDDLYGGTYRMFTRIYA 112
Query: 123 QSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTT 182
S VD +D E F+++ + V +E+PTNPL K+ DI I + K
Sbjct: 113 NSGIKFHFVDMNDLENFESLI--NENTKLVWVETPTNPLMKIADIAEIAKITK--KHKIL 168
Query: 183 VVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
VDNT + PL L G D+V SATKYL GH D++ G +I K E+ S+L+F
Sbjct: 169 FAVDNTFATPYLQKPLDL--GADIVMHSATKYLGGHSDVIAGALIVKDEELGSQLHFQQF 226
Query: 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVG 302
+TGA L PMDS+L++RG+KTL +R+ + N +A +L N K K + G
Sbjct: 227 ATGATLGPMDSFLVLRGIKTLHLRVQRHCENGAKVAEFLLNHS--------KIEKVYYPG 278
Query: 303 LRSNPDFKLHKSFN-NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
L S+P + K G G +++F S + + + +K+ ++ + S G V SL + P
Sbjct: 279 LPSHPYHDIAKKQMIGGFGGMVTFTFKSGKKEEAISFLEKVKVFTLAESLGGVESLANHP 338
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+HASI + RKE +DLVRL G+E+ DL DL A+
Sbjct: 339 ALMTHASIPEDKRKEIGITDDLVRLSVGVEDAEDLIADLKQAL 381
>gb|AAX99219.1| cystathionine gamma-synthase [Helicobacter pylori]
Length = 380
Score = 608 bits (1568), Expect = e-172, Method: Composition-based stats.
Identities = 132/403 (32%), Positives = 206/403 (51%), Gaps = 27/403 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T +++ G D + +V P+Y ++T++ D + Y+YSRSGNPTR L+ I
Sbjct: 2 HMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIG-HHKGYEYSRSGNPTRFALEELIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SG+ + + LL D+ ++ GDD+YGGT RL N +
Sbjct: 61 DLEGGVK--GFAFASGLAGIHAVFS---LLQSGDH----VLLGDDVYGGTFRLFNKVLVK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +DTSD + K + K + LE+P+NPL K+ D+ + K
Sbjct: 112 NGLSCTIIDTSDLSQIKKAIKPNTK--ALYLETPSNPLLKITDLAQCASVAKD--HGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + NPL L G D+V S TKYL GH D++ G++ + +A ++ F N+
Sbjct: 168 IVDNTFATPYYQNPLLL--GADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G L P DSWLL RG+KTLG+R+ Q+NA+ +A +LE + K + + GL
Sbjct: 226 IGGVLGPQDSWLLQRGIKTLGLRMQAHQKNALCVAEFLE--------KHPKVERVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P+++L K G +LSF + + V S L ++ + S G V SL+ +P
Sbjct: 278 PTHPNYELAKKQMRGFSGMLSFTLKNDSEATPFVES--LKLFILGESLGGVESLVGVPAF 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HA I R+ + LVRL GIE+ DL +DL A
Sbjct: 336 MTHACIPKTQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAK 378
>ref|YP_626847.1| cystathionine gamma-synthase/cystathionine beta-lyase [Helicobacter
pylori HPAG1]
gb|ABF84173.1| cystathionine gamma-synthase [Helicobacter pylori HPAG1]
Length = 380
Score = 608 bits (1568), Expect = e-172, Method: Composition-based stats.
Identities = 133/405 (32%), Positives = 208/405 (51%), Gaps = 27/405 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R+ T +++ G D + +V P+Y ++T++ D + Y+YSRSGNPTR L+ I
Sbjct: 2 RMQTKLIHGGISEDTTTGAVSVPIYQTSTYRQDAIG-HHKGYEYSRSGNPTRFALEELIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SG+ + + LL D+ ++ GDD+YGGT RL N +
Sbjct: 61 DLEGGVK--GFAFASGLAGIHAVFS---LLQSGDH----VLLGDDVYGGTFRLFNKVLVK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +DTSD + K + K + LE+P+NPL K+ D+ + K
Sbjct: 112 NGLSCTIIDTSDLSQIKKAIKQNTK--ALYLETPSNPLLKITDLAQCASVAKD--HGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + NPL L G D+V S TKYL GH D++ G++ + ++ ++ F N+
Sbjct: 168 IVDNTFATPYYQNPLLL--GADIVVHSGTKYLGGHSDVVAGLVTTNNEALSQEIAFFQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G L P DSWLL RG+KTL +R+ Q+NA+ +A +LE + K K + GL
Sbjct: 226 IGGVLGPQDSWLLQRGIKTLALRMEAHQKNALCVAEFLE--------KHPKVEKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P+++L K+ G +LSF + + V S L ++ + S G V SL+ +P
Sbjct: 278 PTHPNYELAKAQMRGFSGMLSFTLKNDSEATLFVES--LKLFILGESLGGVESLVGIPAF 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+HA I E R+ + LVRL GIE+ DL +DL A
Sbjct: 336 MTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG 380
>ref|ZP_02161506.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein [Kordia
algicida OT-1]
gb|EDP96652.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein [Kordia
algicida OT-1]
Length = 383
Score = 607 bits (1567), Expect = e-172, Method: Composition-based stats.
Identities = 126/403 (31%), Positives = 205/403 (50%), Gaps = 25/403 (6%)
Query: 5 RLDTVVVNTGSQNDQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T ++ + D+ + A + P+Y ++T+ + Y+YSR+ NPTR+ L++ +
Sbjct: 2 KFNTKTIHGKQEPDKAYGAVMQPIYQTSTYAQSTPGGH-KGYEYSRTHNPTRNALENALA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ LA +SG+ A+D I++ LL D +I+ +DLYGGT RL +
Sbjct: 61 SIEN--GNYGLAFASGLAAIDAIIK---LLKPGDE----VISTNDLYGGTYRLFTRIFEG 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
V + K ++ + + +E+PTNP+ ++DI + K +
Sbjct: 112 FGIKFHFVGMENVAKIESYV--NENTKLIWVETPTNPMMNIIDIEAVSVIAK--KHQVML 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + PL L G D+V SATKY+ GH DL+ G +I EIA KLYF+ N+
Sbjct: 168 AVDNTFATPYLQRPLDL--GADIVMHSATKYIGGHSDLVMGALIVNDKEIADKLYFIQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
+GA PMDS+L +RG+KTL VR+ + N +A +L N K K + GL
Sbjct: 226 SGAICGPMDSFLALRGIKTLHVRMQRHCENGKAIAVYLANH--------PKIEKVYWPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+++P+ + K + G ++SF + + + + L I+ + S G V SL P
Sbjct: 278 KNHPNHAIVKKQMDDFGGMISFVIKGNNYEEAIKIVENLKIFTLAESLGGVESLAGHPAS 337
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI E R++ + L+RL GIE++ DL DL A+
Sbjct: 338 MTHASIPKEEREKIGVVDALIRLSVGIEDVDDLIADLEQALSK 380
>ref|ZP_01733647.1| cystathionine gamma-lyase [Flavobacteria bacterium BAL38]
gb|EAZ96716.1| cystathionine gamma-lyase [Flavobacteria bacterium BAL38]
Length = 381
Score = 607 bits (1566), Expect = e-172, Method: Composition-based stats.
Identities = 138/402 (34%), Positives = 211/402 (52%), Gaps = 24/402 (5%)
Query: 5 RLDTVVVNTGSQNDQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T ++ G +++ A +PPV+ ++T+ + +Y+YSR+ NPTR+ L+ +
Sbjct: 2 KFNTKTIHGGQHHEKVTGAVMPPVFQTSTYVQSSPGKPVGDYEYSRAANPTRTALEDALA 61
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ LA SSG+ A D +LR + D IIA DDLYGGT RL +
Sbjct: 62 SIEN--GARGLAFSSGLAATDCLLR---MFKAGDE----IIAMDDLYGGTYRLFTRLYKD 112
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
S VD +D EKF+++ + V +E+PTNPL K+ DI I + K +
Sbjct: 113 SGIKFHFVDMNDLEKFQSLI--NENTKLVWVETPTNPLMKLADIAAIAQITK--KHNILF 168
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + PL L G D+V SATKYL GH D++ G +I K + +L+F +
Sbjct: 169 AVDNTFATPYLQKPLDL--GADIVMHSATKYLGGHSDVIAGALIIKDKALGEELHFKQFA 226
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TGA L PMDS+L++RG+KTL +R+ + N +A +L+N + + GL
Sbjct: 227 TGATLGPMDSFLVLRGIKTLHLRVQRHCENGEKVAEYLDNHSL--------VERVYYPGL 278
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+P ++ K +G G +++F S + + + L ++ + S G V SL + P
Sbjct: 279 ASHPFHEIAKKQMSGFGGMVTFTFKSGKKEDAIEFLENLKVFTLAESLGGVESLANHPAL 338
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE +DLVRL GIE+I DL DL A
Sbjct: 339 MTHASIPEDKRKEVGISDDLVRLSVGIEDIEDLLADLEQAFK 380
>ref|NP_206906.1| cystathionine gamma-synthase/cystathionine beta-lyase [Helicobacter
pylori 26695]
sp|P56069|METB_HELPY Cystathionine gamma-synthase (CGS) (O-succinylhomoserine
(thiol)-lyase)
gb|AAD07176.1| cystathionine gamma-synthase (metB) [Helicobacter pylori 26695]
Length = 380
Score = 607 bits (1566), Expect = e-172, Method: Composition-based stats.
Identities = 133/405 (32%), Positives = 207/405 (51%), Gaps = 27/405 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R+ T +++ G D + +V P+Y ++T++ D + Y+YSRSGNPTR L+ I
Sbjct: 2 RMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRH-KGYEYSRSGNPTRFALEELIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SG+ + + LL D+ ++ GDD+YGGT RL N +
Sbjct: 61 DLEGGVK--GFAFASGLAGIHAVFS---LLQSGDH----VLLGDDVYGGTFRLFNQVLVK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +DTSD + K + K + LE+P+NPL K+ D+ + K
Sbjct: 112 NGLSCTIIDTSDISQIKKAIKPNTK--ALYLETPSNPLLKITDLAQCASVAKD--HGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + NPL L G D+V S TKYL GH D++ G++ + +A ++ F N+
Sbjct: 168 IVDNTFATPYYQNPLLL--GADIVAHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G L P DSWLL RG+KTLG+R+ Q+NA+ +A +LE + K + + GL
Sbjct: 226 IGGVLGPQDSWLLQRGIKTLGLRMEAHQKNALCVAEFLE--------KHPKVERVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P+++L K G +LSF + + V S L ++ + S G V SL+ +P
Sbjct: 278 PTHPNYELAKKQMRGFSGMLSFTLKNDSEAVAFVES--LKLFILGESLGGVESLVGIPAF 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+HA I R+ + LVRL GIE+ DL +DL A
Sbjct: 336 MTHACIPKTQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG 380
>ref|ZP_01120255.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[Robiginitalea biformata HTCC2501]
gb|EAR16783.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[Robiginitalea biformata HTCC2501]
Length = 388
Score = 606 bits (1564), Expect = e-171, Method: Composition-based stats.
Identities = 129/405 (31%), Positives = 207/405 (51%), Gaps = 29/405 (7%)
Query: 5 RLDTVVVNTGSQNDQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R ++ ++ G D+ + A +PP+Y ++T+ + Q Y+YSRSGNPTR L+ +
Sbjct: 6 RFNSRTIHGGQHPDKAYGAVMPPIYQTSTYAQSSPGQH-QGYEYSRSGNPTRHALEESLA 64
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ LA +SG+ A+D +++ LL D ++A +DLYGG+ RL +
Sbjct: 65 SIEN--GRFGLAFASGLAAMDAVVK---LLKPGDE----VLATNDLYGGSYRLFRKVFEP 115
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ D E + V +E+PTNP+ +V+DI + C S +
Sbjct: 116 LGIRFRFLGMQDAEAVASAIGPET--RLVWVETPTNPMMQVIDIAAVAE--SCRSRGVLL 171
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + PL+L G D+V SATKYL GH D++ G ++ K E+A +LYF+ N+
Sbjct: 172 AVDNTFATPYLQRPLEL--GADIVMHSATKYLGGHSDVVAGGLVVKDKELADRLYFIQNA 229
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
+GA PMDS+L++RG+KTL VR+ + N +A +L G + + G
Sbjct: 230 SGAVCGPMDSFLVLRGIKTLHVRMQRHCENGRAVAEFLAGHPG--------VERVYWPGF 281
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGS--FEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
+P+ + G G ++SF FE + R+V + L ++ + S G V SL P
Sbjct: 282 PDHPNHDIAAKQMTGFGGMISFVPRGARFEDAVRIVEN--LRVFTLAESLGGVESLAGHP 339
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI + R++ + L+RL GIE+ DL +DL A+
Sbjct: 340 ASMTHASIPKDEREKSGVTDSLIRLSVGIEDAADLTEDLERALAA 384
>ref|YP_001487586.1| cystathionine beta-lyase [Bacillus pumilus SAFR-032]
gb|ABV63026.1| cystathionine beta-lyase [Bacillus pumilus SAFR-032]
Length = 382
Score = 606 bits (1564), Expect = e-171, Method: Composition-based stats.
Identities = 141/401 (35%), Positives = 225/401 (56%), Gaps = 27/401 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T+++++G+ D+ + +V P+Y +T+K E Y+YSR+ NPTR+ L+ I
Sbjct: 2 KRKTMMIHSGTTGDEKTGAVSVPIYQVSTYKQPKAGEH-TGYEYSRTANPTRTALETAIR 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L N A SGM A+ ++ +L N D+ I+ DD+YGGT R++ +
Sbjct: 61 DLEG--GANGYAFGSGMAAITAVM---MLFNSGDH----IVLTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ VDTSD E K K V +ESPTNPL K+ D+ + + K + +
Sbjct: 112 IDIQATFVDTSDPEAVKKAILPETK--AVYIESPTNPLLKMTDLKAVGQLTK--EANILM 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + P++ G D+V SATKYL GH D++GG++++ T E+ +L+FV NS
Sbjct: 168 IVDNTFFTPYFQRPIE--YGADIVLHSATKYLGGHSDVVGGLVVTATEELGEELHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DSWLL+RG+KTLG+R+ Q+NA +A +LE T+ + GL
Sbjct: 226 TGGILGPQDSWLLMRGIKTLGLRMEAHQQNAQKIAEFLEQH--------PAVTRVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P +L K+ +G G ++SF+ G EH +S +L ++ + S G V SL+S+P +
Sbjct: 278 DAHPGHELAKTQASGYGGMISFDIGKEEHVDVFLS--QLKLFTIAESLGAVESLISVPAR 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+HASI + R+E + L+R+ GIE++ DL D+ +
Sbjct: 336 MTHASIPKDRREELGITDGLIRISVGIEDVDDLLNDMKQGL 376
>ref|YP_002774266.1| cystathionine gamma-lyase [Brevibacillus brevis NBRC 100599]
dbj|BAH45762.1| cystathionine gamma-lyase [Brevibacillus brevis NBRC 100599]
Length = 377
Score = 605 bits (1562), Expect = e-171, Method: Composition-based stats.
Identities = 142/401 (35%), Positives = 222/401 (55%), Gaps = 27/401 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R+ T +++ G D H+ +V P+Y +T+K + + ++YSR+GNPTR L+ I
Sbjct: 2 RIKTRLIHGGIDGDPHTGAVSVPIYQVSTYKQEAIGVH-KGFEYSRTGNPTRHALETYIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
++ A SGM AL IL + N D+ ++ GDD+YGGT R++ +
Sbjct: 61 EIEG--GARGFAFGSGMAALSTILS---MFNKGDH----LVVGDDVYGGTYRVVTRVFSR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +VDTSD + + K +++E+PTNPL KV DI + K + +
Sbjct: 112 MGLEATYVDTSDLAAVEAAIRPETK--AIIMETPTNPLLKVSDISALAGIAK--AKGVLL 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VVDNT M+ NPL L G D+V+ SATKYL GH D++ G++++K ++ L+FV N+
Sbjct: 168 VVDNTFMTPYWQNPLDL--GADIVFHSATKYLGGHSDVVAGLVVAKDAQVGEDLHFVQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G L P DSWLL+RG+KTLG+R+ + + NA LA WL + + GL
Sbjct: 226 IGGVLGPQDSWLLLRGMKTLGIRMEEHEHNARTLAKWLSERSD--------IKRVIYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ +L + G G ++SF+ GS E + +++ K+ + + S G V SL+S+P +
Sbjct: 278 SSHSGHELIQKQARGFGGMISFDVGSAERADEVLA--KVKYYTLAESLGAVESLISVPAR 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+HASI E R E + LVR+ GIE++ DL +DL A+
Sbjct: 336 MTHASIPAERRAELGITDGLVRISVGIEDVQDLIEDLDQAL 376
>ref|YP_630264.1| Cys/Met metabolism PLP-dependent enzyme [Myxococcus xanthus DK
1622]
gb|ABF92425.1| Cys/Met metabolism PLP-dependent enzyme [Myxococcus xanthus DK
1622]
Length = 381
Score = 604 bits (1559), Expect = e-171, Method: Composition-based stats.
Identities = 135/406 (33%), Positives = 215/406 (52%), Gaps = 28/406 (6%)
Query: 5 RLDTVVVNTGSQNDQHSAS-VPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R DT+ ++ G + D + + + PVYL++T+ D E + Y+YSR+ NPTR LQ +
Sbjct: 2 RFDTLAIHAGQEPDPTTGAIMTPVYLTSTYVQDGPGEH-KGYEYSRTQNPTRKALQDCLA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SG+ D+++ +L+ D+ ++ DD+YGGT RL + ++
Sbjct: 61 ALEGA--KYGAAFASGLAGTDMLMH---MLDSGDH----VVVSDDVYGGTFRLFDKVFRR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ VD S E F+ K V +ESPTNP+ K++D+ RI K +
Sbjct: 112 AGLHFSFVDLSKPENFEAAITP--KTKMVWVESPTNPMLKLIDLARIAEVAK--KRNILS 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
V DNT M+ PL L G DVV S TKY+NGH D++GG + + ++A K+YF+ N+
Sbjct: 168 VADNTFMTPYFQRPLDL--GFDVVAHSTTKYINGHSDVVGGFVCTSREDVAEKMYFLQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G DS++++RG+KTL VR+ + NAM +A +L + K K + GL
Sbjct: 226 VGGVSGAFDSFMVLRGVKTLHVRMDRHASNAMKVAQFLASH--------PKVKKVTYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFET-GSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPC 362
++P L K +G G +++F+ G E ++ + + K ++A S G V SL+ P
Sbjct: 278 EAHPQHALAKQQMSGFGGMVTFDIQGGLEAARTFLKTVK--VFACAESLGGVESLIEHPA 335
Query: 363 KMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+HASI E R++ + +RL GIE+ DL DL A+ A
Sbjct: 336 IMTHASIPKETREQLGITDGFIRLSVGIEDARDLVDDLSQALDAAK 381
>ref|NP_266937.1| cystathionine gamma-synthase/cystathionine beta-lyase [Lactococcus
lactis subsp. lactis Il1403]
ref|YP_001033049.1| cystathionine gamma-synthase/cystathionine beta-lyase [Lactococcus
lactis subsp. cremoris MG1363]
sp|P0A4K2|METC_LACLA Cystathionine beta-lyase (CBL) (Beta-cystathionase) (Cysteine
lyase)
sp|A2RM21|METC_LACLM Cystathionine beta-lyase (CBL) (Beta-cystathionase) (Cysteine
lyase)
gb|AAF14693.1|AF131880_1 cystathionine beta-lyase MetC [Lactococcus lactis subsp. cremoris]
gb|AAF36088.1|AF170901_1 cystathionine beta/gamma-lyase [Lactococcus lactis subsp. cremoris]
gb|AAK04879.1|AE006311_10 cystathionine gamma-synthase (EC 4.2.99.9) [Lactococcus lactis
subsp. lactis Il1403]
emb|CAL98348.1| cystathionine beta-lyase [Lactococcus lactis subsp. cremoris
MG1363]
Length = 380
Score = 604 bits (1559), Expect = e-171, Method: Composition-based stats.
Identities = 142/405 (35%), Positives = 217/405 (53%), Gaps = 27/405 (6%)
Query: 3 IKRLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQ 61
+ + T V++ G D+ + +V P+Y ++T+K + + + Y+YSRSGNPTR L+
Sbjct: 1 MTSIKTKVIHGGISTDKTTGAVSVPIYQTSTYKQNGLGQ-PKEYEYSRSGNPTRHALEEL 59
Query: 62 IGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFK 121
I L Q A SSG+ + +L L + D+ II DD+YGGT RL++
Sbjct: 60 IADLEGGVQ--GFAFSSGLAGIHAVLS---LFSAGDH----IILADDVYGGTFRLMDKVL 110
Query: 122 QQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDT 181
++ + VD S+ + K F+ K + E+P+NPL KV+DI I K + D
Sbjct: 111 TKTGIIYDLVDLSNLDDLKAAFKEETK--AIYFETPSNPLLKVLDIKEISAIAK--AHDA 166
Query: 182 TVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVI 241
+VDNT + P+ L G D+V SATKYL GH D++ G++ + + E+AS++ F+
Sbjct: 167 LTLVDNTFATPYLQQPIAL--GADIVLHSATKYLGGHSDVVAGLVTTNSKELASEIGFLQ 224
Query: 242 NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFV 301
NS GA L P DSWL+ RG+KTL +R+ NA +A +LE S +K +
Sbjct: 225 NSIGAVLGPQDSWLVQRGIKTLALRMEAHSANAQKIAEFLETSKA--------VSKVYYP 276
Query: 302 GLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
GL S+P ++ K + G ++SFE K V + LS + + S G V SL+ +P
Sbjct: 277 GLNSHPGHEIAKKQMSAFGGMISFELTDENAVKDFVEN--LSYFTLAESLGGVESLIEVP 334
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI ELR+E + L+RL G+E I DL D+ A+
Sbjct: 335 AVMTHASIPKELREEIGIKDGLIRLSVGVEAIEDLLTDIKEALEK 379
>ref|ZP_01886342.1| Cys/Met metabolism PLP-dependent enzyme [Pedobacter sp. BAL39]
gb|EDM34452.1| Cys/Met metabolism PLP-dependent enzyme [Pedobacter sp. BAL39]
Length = 379
Score = 603 bits (1556), Expect = e-171, Method: Composition-based stats.
Identities = 118/402 (29%), Positives = 198/402 (49%), Gaps = 25/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T ++ G + D + +V P+Y ++T+ ++ + ++YSR NPTR L+ +
Sbjct: 2 KFATKAIHAGQEPDPTTGAVMTPIYQTSTYWQKSPGDN-KGFEYSRGTNPTRKALEDCLA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + LA SSGM A D +++ LL D +I G+DLYGG+ R+ +
Sbjct: 61 ALENA--KYGLAFSSGMGATDAVMK---LLQPGDE----VITGNDLYGGSYRIFTKIYAK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+D S E DK V +E+PTNP +V+DI + + K +
Sbjct: 112 YGIKFHFIDLSKPENVLPYI--NDKTKLVWIETPTNPTMQVIDIEGVAKITK--ERKLLL 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT S NP+ L G D+V S TKY+ GH D++ G ++ ++ L+F+ N+
Sbjct: 168 TVDNTFASPYLQNPMDL--GADIVMHSVTKYIGGHSDVVMGALLVNDDQLYKDLWFIYNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA P D++L++RG+KTL +R+ N +AH+L+N + K + G
Sbjct: 226 CGATPGPQDAFLVLRGIKTLHLRMKAHCENGEKVAHFLKNH--------PRIDKIYWPGF 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+P+ + K G G ++S + + + ++ + S G V SL++ P
Sbjct: 278 EDHPNHDIAKKQMRGFGGMVSITLKGADLQETFRIASSFKVFTLAESLGGVESLINHPTS 337
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+H SI E R++ ++L+RL G+E+I DL DL A+
Sbjct: 338 MTHGSIPKEEREKVGVTDNLLRLSVGVEDIDDLIADLEQALK 379
>ref|YP_001909598.1| cystathionine gamma-synthase/cystathionine beta-lyase [Helicobacter
pylori Shi470]
gb|ACD47568.1| cystathionine gamma-synthase/cystathionine beta-lyase [Helicobacter
pylori Shi470]
Length = 380
Score = 603 bits (1556), Expect = e-170, Method: Composition-based stats.
Identities = 133/405 (32%), Positives = 205/405 (50%), Gaps = 27/405 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R+ T +++ G D + +V P+Y ++T++ + Y+YSRSGNPTR L+ I
Sbjct: 2 RMQTKLIHGGISEDAATGAVSVPIYQTSTYRQGAIGRH-KGYEYSRSGNPTRFALEELIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SG+ + + LL D+ ++ GDD+YGGT RL N +
Sbjct: 61 DLEGGVK--GFAFASGLAGIHAVFS---LLQSGDH----VLLGDDVYGGTFRLFNKVLVK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +DTSD + K + K + LE+P+NPL K+ D+ + K
Sbjct: 112 NGLSCTIIDTSDLSQIKKAIKPNTK--ALYLETPSNPLLKITDLVQCASVAKD--HGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + NPL L G D+V S TKYL GH D++ G++ + +A ++ F N+
Sbjct: 168 IVDNTFATPYCQNPLLL--GADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G L P DSWLL RG+KTLG+R+ Q+NA+ +A +LE + K K + GL
Sbjct: 226 IGGVLGPQDSWLLQRGIKTLGLRMEAHQKNALCVAEFLE--------KHPKVEKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P+ +L K G +LSF + + V S L ++ + S G V SL+ +P
Sbjct: 278 SAHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVES--LKLFILGESLGGVESLVGVPAL 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+HA I R+ + LVRL GIE+ DL +DL A
Sbjct: 336 MTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG 380
>ref|YP_863450.1| Cys/Met metabolism pyridoxal-phosphate-dependent enzyme [Gramella
forsetii KT0803]
emb|CAL68383.1| Cys/Met metabolism pyridoxal-phosphate-dependent enzyme [Gramella
forsetii KT0803]
Length = 380
Score = 603 bits (1556), Expect = e-170, Method: Composition-based stats.
Identities = 128/404 (31%), Positives = 207/404 (51%), Gaps = 30/404 (7%)
Query: 5 RLDTVVVNTGSQN-DQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQI 62
+ +T ++ G +N D + + +PP+Y +TT+ + ++YSRSGNPTR+ L+ +
Sbjct: 2 KFNTKTIHGGQENVDPAYGSVMPPIYQTTTYSQSTPGGH-KGFEYSRSGNPTRANLEKSL 60
Query: 63 GKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQ 122
L LA SG+ A+D +L+ L D II+ +DLYGG+ RL +
Sbjct: 61 ASLEN--GNFGLAFGSGLAAIDAVLK---LFKPGDE----IISTNDLYGGSYRLFTRIFE 111
Query: 123 QSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTT 182
V D E + + + +E+PTNP+ ++DI + + K D
Sbjct: 112 GLGIKFHFVGMQDAEGIEEYI--NENTKLIWVETPTNPMMNIIDIAEVSKIAK--KHDLL 167
Query: 183 VVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
+ VDNT + PL L G D++ SATKYL GH D++ G ++ E+A KLYF+ N
Sbjct: 168 LAVDNTFATPYLQQPLGL--GADIIMHSATKYLGGHSDVVMGGLVVNDKELADKLYFIQN 225
Query: 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVG 302
++GA P DS+L++RG+KTL +R+ + N +A +L ++ K K + G
Sbjct: 226 ASGAICGPQDSFLVLRGIKTLHIRMQRHCENGAAVAKFLRSN--------PKVDKVYWPG 277
Query: 303 LRSNPDFKLHKSFNNGPGAVLSFETG--SFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
+P+ + + +G G ++SF T + E + ++V KL I+ + S G V SL
Sbjct: 278 FEDHPNHDIARKQMSGFGGMISFTTKANTLESATKIVE--KLKIFTLAESLGGVESLAGH 335
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
P M+HASI R++ + L+RL GIE+ DL DL A+
Sbjct: 336 PASMTHASIPKVDREKTGVVDSLIRLSVGIEDEEDLIADLSQAI 379
>ref|NP_834078.1| cystathionine beta-lyase [Bacillus cereus ATCC 14579]
ref|ZP_02525947.1| cystathionine beta-lyase [Bacillus cereus AH1134]
gb|AAP11279.1| Cystathionine beta-lyase [Bacillus cereus ATCC 14579]
Length = 377
Score = 603 bits (1555), Expect = e-170, Method: Composition-based stats.
Identities = 140/402 (34%), Positives = 222/402 (55%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I
Sbjct: 2 RAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ E+ + + K + +E+PTNPL K+ DI +I K D
Sbjct: 112 FGIEHTFVDTTNLEEVEEAIRPNTK--AIYVETPTNPLLKITDIKKISTLAK--EKDLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ + +L NG GA++SF+ S E +++ KL + + S G V SL+S+P +
Sbjct: 278 ESHQNHELATEQANGFGAIISFDVDSEETLNKVLE--KLQYFTLAESLGAVESLISIPSQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>ref|NP_980747.1| cystathionine beta-lyase [Bacillus cereus ATCC 10987]
gb|AAS43355.1| cystathionine beta-lyase [Bacillus cereus ATCC 10987]
Length = 377
Score = 603 bits (1555), Expect = e-170, Method: Composition-based stats.
Identities = 141/402 (35%), Positives = 223/402 (55%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I
Sbjct: 2 RAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ E+ + + K + +E+PTNPL K+ DI +I K D
Sbjct: 112 FGIEHTFVDTTNLEEVEEAIRPNTK--AIYVETPTNPLLKITDIKKISTLAK--EKDLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ + +L NG GA++SF+ S E +++ KKL + + S G V SL+S+P +
Sbjct: 278 ESHQNHELATEQANGFGAIISFDVDSEETLNKVL--KKLQYFTLAESLGAVESLISIPSQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>ref|ZP_02578916.1| cystathionine beta-lyase [Bacillus cereus B4264]
Length = 377
Score = 603 bits (1555), Expect = e-170, Method: Composition-based stats.
Identities = 141/402 (35%), Positives = 222/402 (55%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I
Sbjct: 2 RAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ E+ K + K + +E+PTNPL K+ DI +I K D
Sbjct: 112 FGIEHTFVDTTNLEEVKEAIRPNTK--AIYVETPTNPLLKITDIKKISTLAK--EKDLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ + +L NG GA++SF+ S E +++ KL + + S G V SL+S+P +
Sbjct: 278 ESHQNHELATEQANGFGAIISFDVDSEETLNKVLE--KLQYFTLAESLGAVESLISIPSQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>ref|ZP_02254620.1| cystathionine beta-lyase [Bacillus cereus AH187]
ref|ZP_02596382.1| cystathionine beta-lyase [Bacillus cereus H3081.97]
Length = 377
Score = 602 bits (1554), Expect = e-170, Method: Composition-based stats.
Identities = 139/402 (34%), Positives = 222/402 (55%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I
Sbjct: 2 RAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ E+ + + K + +E+PTNPL K+ DI +I K D
Sbjct: 112 FGIEHTFVDTTNLEEVEEAIRPNTK--AIYVETPTNPLLKITDIKKISTLAK--EKDLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ + +L NG GA++SF+ S E +++ +L + + S G V SL+S+P +
Sbjct: 278 ESHQNHELATEQANGFGAIISFDVDSEETLNKVLE--RLQYFTLAESLGAVESLISIPSQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>ref|ZP_03983763.1| cystathionine gamma-synthase/cystathionine beta-lyase [Enterococcus
faecalis HH22]
gb|EEI58143.1| cystathionine gamma-synthase/cystathionine beta-lyase [Enterococcus
faecalis HH22]
Length = 394
Score = 602 bits (1553), Expect = e-170, Method: Composition-based stats.
Identities = 134/406 (33%), Positives = 205/406 (50%), Gaps = 27/406 (6%)
Query: 2 PIKRLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
P + +T +++ G D + +V P+Y ++TF+ + + + Y+YSRSGNPTR L+
Sbjct: 15 PFMKFNTKLIHGGISKDTTTGAVSVPIYQTSTFEQNGVGQ-PKEYEYSRSGNPTRHALET 73
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
I +L + A SSG+ + I+ + D+ I+ GDD+YGG+ RLL+
Sbjct: 74 LIAELEG--GSHGFAFSSGLAGIHAIIS---MFGPEDH----ILLGDDVYGGSFRLLDKV 124
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
+ V+ SD + Q K + LE+P+NPL K+ DI + K
Sbjct: 125 FVANGLSYTIVNASDLSTIEAAIQPNTK--ALFLETPSNPLLKITDIEAAAKLAK--KHQ 180
Query: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
+VDNT + PL L G D+V S TKYL GH D++ G++++ PE A K+ F+
Sbjct: 181 LLTIVDNTFATPYFQRPLAL--GADIVVHSGTKYLGGHSDVVSGLVVTNHPESAEKIAFL 238
Query: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
N+ GA L P DSWL+ R LKTLGVR+ +NA +A +LE +
Sbjct: 239 QNAIGAVLGPHDSWLVQRSLKTLGVRMAAHAQNAQKIAEFLEAH--------PAVATVYY 290
Query: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
GL S+P ++ + +G ++SFE E V + L I+ + S G V SL+ +
Sbjct: 291 PGLASHPGHEIAQKQMSGFSGMISFELAKDEQVVPFVEA--LEIFTLAESLGGVESLIEV 348
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
P M+HASI E R+ + L+RL GIE + DL DL +
Sbjct: 349 PAIMTHASIPKENREAVGIKDGLIRLSVGIEAVEDLLADLEKGLQA 394
>ref|YP_085695.1| cystathionine beta-lyase [Bacillus cereus E33L]
gb|AAU16153.1| cystathionine beta-lyase [Bacillus cereus E33L]
Length = 377
Score = 602 bits (1553), Expect = e-170, Method: Composition-based stats.
Identities = 139/402 (34%), Positives = 222/402 (55%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I
Sbjct: 2 RAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ E+ + + K + +E+PTNPL K+ DI +I K D
Sbjct: 112 FGIEHTFVDTTNLEEVEEAIRPNTK--AIYVETPTNPLLKITDIKKISTLAK--EKDLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ + +L NG GA++SF+ S E +++ +L + + S G V SL+S+P +
Sbjct: 278 ASHQNHELAAEQANGFGAIISFDVDSEETLNKVLE--RLQYFTLAESLGAVESLISIPSQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>ref|NP_846819.1| cystathionine beta-lyase [Bacillus anthracis str. Ames]
ref|YP_021246.1| cystathionine beta-lyase [Bacillus anthracis str. 'Ames Ancestor']
ref|YP_030516.1| cystathionine beta-lyase [Bacillus anthracis str. Sterne]
ref|ZP_02217370.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0488]
ref|ZP_02392932.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0442]
ref|ZP_02396882.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0193]
ref|ZP_02609245.1| cystathionine beta-lyase [Bacillus anthracis Tsiankovskii-I]
ref|ZP_02878635.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0465]
ref|ZP_02897909.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0389]
ref|ZP_02935559.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0174]
gb|AAP28305.1| cystathionine beta-lyase [Bacillus anthracis str. Ames]
gb|AAT33721.1| cystathionine beta-lyase [Bacillus anthracis str. 'Ames Ancestor']
gb|AAT56567.1| cystathionine beta-lyase [Bacillus anthracis str. Sterne]
gb|EDR17067.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0488]
gb|EDR88824.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0193]
gb|EDR92799.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0442]
gb|EDS96572.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0389]
gb|EDT19359.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0465]
gb|EDT66661.1| Cys/Met metabolism PLP-dependent enzyme [Bacillus anthracis str.
A0174]
Length = 377
Score = 601 bits (1551), Expect = e-170, Method: Composition-based stats.
Identities = 138/402 (34%), Positives = 221/402 (54%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I
Sbjct: 2 RAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ E+ + + K + +E+PTNPL K+ DI +I K
Sbjct: 112 FGIEHTFVDTTNLEEVEEAIRPNTK--AIYVETPTNPLLKITDIKKISTLAK--EKGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ + +L NG GA++SF+ S E +++ +L + + S G V SL+S+P +
Sbjct: 278 ASHQNHELATEQANGFGAIISFDVDSEETLNKVLE--RLQYFTLAESLGAVESLISIPSQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>ref|YP_038423.1| cystathionine beta-lyase [Bacillus thuringiensis serovar konkukian
str. 97-27]
ref|YP_896685.1| cystathionine beta-lyase [Bacillus thuringiensis str. Al Hakam]
ref|ZP_02262476.1| cystathionine beta-lyase [Bacillus cereus AH820]
ref|ZP_02541013.1| cystathionine beta-lyase [Bacillus cereus W]
ref|ZP_02590105.1| cystathionine beta-lyase [Bacillus cereus NVH0597-99]
ref|ZP_02602192.1| cystathionine beta-lyase [Bacillus cereus 03BB108]
gb|AAT63647.1| cystathionine beta-lyase [Bacillus thuringiensis serovar konkukian
str. 97-27]
gb|ABK87178.1| cystathionine gamma-lyase [Bacillus thuringiensis str. Al Hakam]
Length = 377
Score = 601 bits (1550), Expect = e-170, Method: Composition-based stats.
Identities = 139/402 (34%), Positives = 222/402 (55%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I
Sbjct: 2 RAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ E+ + + K + +E+PTNPL K+ DI +I K D
Sbjct: 112 FGIEHTFVDTTNLEEVEEAIRPNTK--AIYVETPTNPLLKITDIKKISTLAK--EKDLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ + +L NG GA++SF+ S E +++ +L + + S G V SL+S+P +
Sbjct: 278 ASHQNHELATEQANGFGAIISFDVDSEETLNKVLE--RLQYFTLAESLGAVESLISIPSQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>ref|ZP_01719081.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[Algoriphagus sp. PR1]
gb|EAZ80867.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[Algoriphagus sp. PR1]
Length = 381
Score = 601 bits (1550), Expect = e-170, Method: Composition-based stats.
Identities = 119/403 (29%), Positives = 200/403 (49%), Gaps = 25/403 (6%)
Query: 5 RLDTVVVNTGSQNDQHSAS-VPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T ++ G + D + + + P+Y ++T+ + Y+YSR+ NPTR+ LQ+ +
Sbjct: 2 KFGTKAIHAGVEPDPSTGAIMTPIYQTSTYVQRSPGDH-NGYEYSRTHNPTRTALQNNLA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L ++ + SSG+ A+D +++ L N D II+ +DLYGGT RL ++
Sbjct: 61 ALEN--GKHGICFSSGLGAIDAVVK---LFNPGDE----IISTNDLYGGTYRLFTKVFER 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
V D E +K + +E+PTNP+ ++D+ + + K + +
Sbjct: 112 YGIKFHFVPMGDPESITEYI--NEKTKMIWVETPTNPMMNIIDVAGVAKVAK--AHKVLL 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT S NPL G D+V S TKYL GH D++ G ++ EIA +L F+ N+
Sbjct: 168 AVDNTFASPYLQNPLD--QGADIVMHSVTKYLGGHSDVVMGALVLNDDEIADQLVFIQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA P D +L++RG+KTL +R+ + +N +A +L+ K K + G
Sbjct: 226 CGATPGPQDCFLVLRGIKTLHLRMERHSQNGKTIAAYLKTH--------PKVDKVYWPGF 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+P+ + K G ++SF + + + ++A+ S G V SL P
Sbjct: 278 EDHPNHAIAKKQMRDFGGMISFTLVGNKQEDAVKVMENFQLFALAESLGGVESLCGHPAS 337
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI E R++ + L+RL G+E+ DLK+DL A+
Sbjct: 338 MTHASIPKEEREKVGLVDSLIRLSVGVEDAEDLKQDLANALAK 380
>ref|ZP_00741024.1| Cystathionine beta-lyase / Cystathionine gamma-lyase [Bacillus
thuringiensis serovar israelensis ATCC 35646]
ref|ZP_02583591.1| cystathionine beta-lyase [Bacillus cereus G9842]
gb|EAO54692.1| Cystathionine beta-lyase / Cystathionine gamma-lyase [Bacillus
thuringiensis serovar israelensis ATCC 35646]
Length = 377
Score = 600 bits (1549), Expect = e-170, Method: Composition-based stats.
Identities = 140/402 (34%), Positives = 221/402 (54%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I
Sbjct: 2 RAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ E+ + K + +E+PTNPL K+ DI +I K D
Sbjct: 112 FGIEHTFVDTTNLEEVVEAIRPNTK--AIYVETPTNPLLKITDIKKISTLAK--EKDLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ + +L NG GA++SF+ S E +++ KL + + S G V SL+S+P +
Sbjct: 278 ESHQNHELATEQANGFGAIISFDVDSEETLNKVLE--KLQYFTLAESLGAVESLISIPSQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>ref|ZP_00237381.1| trans-sulfuration enzyme family protein [Bacillus cereus G9241]
gb|EAL14921.1| trans-sulfuration enzyme family protein [Bacillus cereus G9241]
Length = 377
Score = 600 bits (1548), Expect = e-170, Method: Composition-based stats.
Identities = 139/402 (34%), Positives = 222/402 (55%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I
Sbjct: 2 RAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ E+ + + K + +E+PTNPL K+ DI +I K D
Sbjct: 112 FGIEHTFVDTTNLEEVEEAIRPNTK--AIYVETPTNPLLKITDIKKISTLGK--EKDLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ + +L NG GA++SF+ S E +++ +L + + S G V SL+S+P +
Sbjct: 278 ESHQNHELATEQANGFGAIISFDVDSEETLNKVLE--RLQYFTLAESLGAVESLISIPSQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>gb|ABO43784.1| cystathionine beta lyase [Lactobacillus reuteri]
Length = 380
Score = 599 bits (1546), Expect = e-169, Method: Composition-based stats.
Identities = 136/405 (33%), Positives = 207/405 (51%), Gaps = 27/405 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T +++ G+ D + +V P+Y S+TF + + + ++YSR+GNPTR+ L+ I
Sbjct: 2 KFNTQLIHGGNSEDPTTGAVSTPIYRSSTFHQHVLGGEPK-WEYSRTGNPTRASLEKLIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+L A +SG A+ L + D+ + G D+YGGT RL+N ++
Sbjct: 61 ELEHGT--AGFAFASGSAAIHATFS---LFSQGDH----FVVGSDVYGGTFRLINKVLKR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VD D E + Q D V E+PTNPL ++ DI I K
Sbjct: 112 FGLEFTVVDMQDLEAVENAIQ--DNTVAVYFETPTNPLLQIADIKAIADIAK--KHGIKT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + N PL L G D+V SATKYL GH D++ G+ ++ EIA +L F+ NS
Sbjct: 168 IVDNTFATPYNQQPLTL--GADIVVHSATKYLGGHSDVVAGLAVTNDDEIAEQLAFLQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G+ L P DSWLL RG+KTLG R+ Q NA + ++L+N + K + GL
Sbjct: 226 IGSTLGPDDSWLLQRGMKTLGARMRAHQENANEVINFLQND--------DHIGKIYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+ P ++ GA++SFE +K+ V S L + + S G + SL+ +P
Sbjct: 278 KDFPGHEIAAKQMRNFGAMISFELKDSLDAKKFVES--LQLIDLAESLGGIESLIEVPAV 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+H SI E+R E ++L+RL GIE+ D+ DL A+ D
Sbjct: 336 MTHGSIPREIRLENGIKDELIRLSVGIEDPEDIIADLQQALKKLD 380
>ref|YP_001270900.1| Cystathionine gamma-synthase [Lactobacillus reuteri F275]
ref|YP_001841277.1| cystathionine beta-lyase [Lactobacillus reuteri F275]
gb|ABQ82563.1| cystathionine gamma-lyase [Lactobacillus reuteri F275]
dbj|BAG24797.1| cystathionine beta-lyase [Lactobacillus reuteri F275]
Length = 380
Score = 599 bits (1546), Expect = e-169, Method: Composition-based stats.
Identities = 136/405 (33%), Positives = 207/405 (51%), Gaps = 27/405 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T +++ G+ D + +V P+Y S+TF + + + ++YSR+GNPTR+ L+ I
Sbjct: 2 KFNTQLIHGGNSEDPTTGAVSTPIYRSSTFHQHVLGGEPK-WEYSRTGNPTRASLEKLIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+L A +SG A+ L + D+ + G D+YGGT RL+N ++
Sbjct: 61 ELEHGT--AGFAFASGSAAIHATFS---LFSQGDH----FVVGSDVYGGTFRLINKVLKR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VD D E + Q D V E+PTNPL ++ DI I K
Sbjct: 112 FGLEFTVVDMQDLEAVENAIQ--DNTVAVYFETPTNPLLQIADIKAIADIAK--KHGIKT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + N PL L G D+V SATKYL GH D++ G+ ++ EIA +L F+ NS
Sbjct: 168 IVDNTFATPYNQQPLTL--GADIVVHSATKYLGGHSDVVAGLAVTNDDEIAEQLAFLQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G+ L P DSWLL RG+KTLG R+ Q NA + ++L+N + K + GL
Sbjct: 226 IGSTLGPDDSWLLQRGMKTLGARMRVHQENANEVINFLQND--------DHIGKIYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+ P ++ GA++SFE +K+ V S L + + S G + SL+ +P
Sbjct: 278 KDFPGHEVAAKQMRNFGAMISFELKDGLDAKKFVES--LQLIDLAESLGGIESLIEVPAV 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+H SI E+R E ++L+RL GIE+ D+ DL A+ D
Sbjct: 336 MTHGSIPREIRLENGIKDELIRLSVGIEDPEDIIADLQQALKKLD 380
>ref|ZP_00604875.1| Cystathionine gamma-synthase [Enterococcus faecium DO]
gb|EAN08794.1| Cystathionine gamma-synthase [Enterococcus faecium DO]
Length = 381
Score = 599 bits (1546), Expect = e-169, Method: Composition-based stats.
Identities = 130/401 (32%), Positives = 203/401 (50%), Gaps = 27/401 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T +++ G D + +V P+Y ++T++ D + + Y+YSRSGNPTR L+ I
Sbjct: 2 HIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQ-PKQYEYSRSGNPTRFALEELIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SSG++ + + L D+ I+ GDD+YGGT RL + +
Sbjct: 61 DLEGGV--RGFAFSSGLSGIHAVFS---LFQAGDH----ILLGDDVYGGTFRLFDKVLTK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +DTS+ +K + + K + LE+P+NPL K+ D+ + V
Sbjct: 112 NGLEYTIIDTSNLDKIEQSIKPNTK--ALYLETPSNPLLKITDLEKSATLAH--QHGLIV 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+ DNT + PL L G D+V S TKYL GH D++ G++ S ++A ++ F N+
Sbjct: 168 IADNTFATPYFQRPLDL--GSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQIGFYQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA L P DSWLL RG+KTL VR+ + Q+NA ++A +L + K + GL
Sbjct: 226 IGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSH--------PAVEKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+ + K +G ++SF + E + V S L ++ + S G V SL+ +P
Sbjct: 278 PDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVES--LQLFTLAESLGGVESLVEIPSV 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+HASI E R+E + L+RL GIE DL DL A
Sbjct: 336 MTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAF 376
>ref|ZP_01689814.1| cystathionine gamma-synthase (CGS)
(O-succinylhomoserine(Thiol)-lyase) [Microscilla marina
ATCC 23134]
gb|EAY29195.1| cystathionine gamma-synthase (CGS)
(O-succinylhomoserine(Thiol)-lyase) [Microscilla marina
ATCC 23134]
Length = 387
Score = 599 bits (1546), Expect = e-169, Method: Composition-based stats.
Identities = 128/404 (31%), Positives = 211/404 (52%), Gaps = 28/404 (6%)
Query: 5 RLDTVVVNTGSQNDQHSAS-VPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T ++ G + + + + + P++ ++T+ + + Q Y+YSR+ NPTR+ L+ +
Sbjct: 2 KFGTKAIHAGVEPEPTTGAIMTPIFQTSTYVQEGLGKPRQGYEYSRTKNPTRTPLESNLA 61
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L ++ L +SGM+A D +++ L D IIA +D+YGGT RL+ +
Sbjct: 62 ALEN--GKHGLCFASGMSATDAVMKT---LKPGDE----IIACNDIYGGTYRLITKVYEP 112
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
V D + S K + E+PTNPL ++DI + + K + +
Sbjct: 113 LGLKPKFVAMGDLANVEAAITSNTK--LIWAETPTNPLLSIIDIAELAKVAK--KHNVLL 168
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + NPL L G D+V SATKYL GH D++ G +++ + E+ +L F+ NS
Sbjct: 169 CVDNTFATPYLQNPLDL--GADLVMHSATKYLGGHSDVVMGALVTSSDELHEQLAFIQNS 226
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA SP D +L++RG+KTL +R+ + + N +A +L N +K K ++GL
Sbjct: 227 CGAVPSPNDCFLMLRGIKTLHIRMDRHELNGKAVAEFLNNH--------DKVDKVYWIGL 278
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGS--FEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
S+ + K G G ++SF + +K+L+ S L ++A+ S G V SL + P
Sbjct: 279 PSHKGHDIVKKQMRGFGGMVSFTLKGNSMDEAKQLMES--LKVFALGESLGGVESLCTHP 336
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI E R+ R + L+RL GIE+ DL +DL A+
Sbjct: 337 ATMTHASIPEEEREARGLKQTLIRLSVGIEDADDLVEDLRQAIE 380
>ref|ZP_01909681.1| Cystathionine gamma-synthase [Plesiocystis pacifica SIR-1]
gb|EDM77347.1| Cystathionine gamma-synthase [Plesiocystis pacifica SIR-1]
Length = 391
Score = 598 bits (1544), Expect = e-169, Method: Composition-based stats.
Identities = 128/405 (31%), Positives = 216/405 (53%), Gaps = 28/405 (6%)
Query: 4 KRLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQI 62
+R++T+ ++ G + + + +V P++ ++T+ E ++YSR+ NPTR L+ +
Sbjct: 12 QRIETLAIHGGQEAEPITGAVMQPIFQTSTYVQRSPGEH-TGFEYSRTQNPTRFALERAM 70
Query: 63 GKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQ 122
L + LA +SG A +++ LL+ D+ +IAGDD+YGGT RL + +
Sbjct: 71 AALEGGT--HGLAFASGCAATTTVIQ---LLDAGDH----VIAGDDIYGGTFRLFDKVMR 121
Query: 123 QSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTT 182
+ VD D + F+ F++ K+ V LE+PTNP+ K+ DI I + C
Sbjct: 122 RRGQRFTFVDPRDLDAFEAAFEARTKM--VWLETPTNPMLKLGDIEAIAKM--CRQRGVL 177
Query: 183 VVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
+VVDNT M+ + PL L G D+V S TKY GH D++GG ++ ++ ++ ++L+F+ N
Sbjct: 178 LVVDNTFMTPVFQRPLDL--GADLVVHSTTKYCGGHSDVVGGAVVMRSAKLHAELHFLQN 235
Query: 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVG 302
S GA P D +L +RGLKTL +R+ + NA +A +LE K + + G
Sbjct: 236 SCGAVPGPQDCYLTLRGLKTLALRMERHASNAQRVAEYLEGHA--------KVERVIYPG 287
Query: 303 LRSNPDFKLHKSFNNGPGAVLSFETG-SFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
L S P +L K +G G ++SF + ++R + + + ++ + S G V SL+ P
Sbjct: 288 LESFPQHELAKRQMSGFGGMVSFYVDSDLDGARRFLEAVR--VFTLAESLGGVESLIEHP 345
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HAS+ R + + +R+ GIE+I DL DL A+
Sbjct: 346 ALMTHASVPKANRDKLGIADGFIRVSVGIEHIDDLIADLERALAA 390
>ref|YP_001376303.1| Cystathionine gamma-synthase [Bacillus cereus subsp. cytotoxis NVH
391-98]
gb|ABS23308.1| Cystathionine gamma-synthase [Bacillus cereus subsp. cytotoxis NVH
391-98]
Length = 377
Score = 598 bits (1544), Expect = e-169, Method: Composition-based stats.
Identities = 140/402 (34%), Positives = 222/402 (55%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T++ + + + Y+YSR+GNPTR+ L+ I
Sbjct: 2 RAKTKLIHGIRIGEPSTGSVNVPIYQTSTYRQEAVGKH-KGYEYSRTGNPTRAALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ II DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDH----IILTDDVYGGTYRVVTKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ ++ T + K + +E+PTNPL K+ DI I F K
Sbjct: 112 FGVEHTFVDTTNLDEVATAVRPNTK--AIYVETPTNPLLKITDIKAISTFAK--EKGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGVLGPQDSFLLLRGLKTLGIRMEEHEVNSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+P+ L K NG GA++SF+ S E +++ K+ + + S G V SL+S+P +
Sbjct: 278 ESHPNHALAKEQANGYGAIISFDVDSEETLNKVLE--KVQYFTLAESLGAVESLISIPAQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGQDLIEDLAQALA 377
>ref|YP_001647006.1| Cystathionine gamma-synthase [Bacillus weihenstephanensis KBAB4]
gb|ABY45378.1| Cystathionine gamma-synthase [Bacillus weihenstephanensis KBAB4]
Length = 377
Score = 598 bits (1543), Expect = e-169, Method: Composition-based stats.
Identities = 143/402 (35%), Positives = 220/402 (54%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTRS L+ I
Sbjct: 2 RAKTKLIHGIRIGESSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRSALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ I DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDHA----ILTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ E+ + K + +E+PTNPL K+ DI +I K D
Sbjct: 112 FGIEHTFVDTTNLEEVVEAIRPNTK--AIYVETPTNPLLKITDIKKISALAK--ENDLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVAVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGILGPQDSFLLLRGLKTLGIRMEEHEINSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ + +L K NG GA++SF+ S E R++ KL + + S G V SL+S+P +
Sbjct: 278 ESHQNHELAKEQANGFGAIISFDVDSEETLNRVLE--KLQYFTLAESLGAVESLISIPSQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>ref|NP_814082.1| cystathionine gamma-synthase/cystathionine beta-lyase [Enterococcus
faecalis V583]
gb|AAO80153.1| cystathionine beta-lyase [Enterococcus faecalis V583]
Length = 378
Score = 598 bits (1542), Expect = e-169, Method: Composition-based stats.
Identities = 133/403 (33%), Positives = 204/403 (50%), Gaps = 27/403 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T +++ G D + +V P+Y ++TF+ + + + Y+YSRSGNPTR L+ I
Sbjct: 2 KFNTKLIHGGISKDTTTGAVSVPIYQTSTFEQNGVGQ-PKEYEYSRSGNPTRHALETLIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+L + A SSG+ + I+ + D+ I+ GDD+YGG+ RLL+
Sbjct: 61 ELEG--GSHGFAFSSGLAGIHAIIS---MFGPEDH----ILLGDDVYGGSFRLLDKVFVA 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ V+ SD + Q K + LE+P+NPL K+ DI + K
Sbjct: 112 NGLSYTIVNASDLSTIEAAIQPNTK--ALFLETPSNPLLKITDIEAAAKLAK--KHQLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + PL L G D+V S TKYL GH D++ G++++ PE A K+ F+ N+
Sbjct: 168 IVDNTFATPYFQRPLAL--GADIVVHSGTKYLGGHSDVVSGLVVTNHPESAEKIAFLQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA L P DSWL+ R LKTLGVR+ +NA +A +LE + GL
Sbjct: 226 IGAVLGPHDSWLVQRSLKTLGVRMAAHAQNAQKIAEFLEAH--------PAVATVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+P ++ + +G ++SFE E V + L I+ + S G V SL+ +P
Sbjct: 278 ASHPGHEIAQKQMSGFSGMISFELAKDEQVVPFVEA--LEIFTLAESLGGVESLIEVPAI 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI E R+ + L+RL GIE + DL DL +
Sbjct: 336 MTHASIPKENREAVGIKDGLIRLSVGIEAVEDLLADLEKGLQA 378
>ref|XP_646022.1| cystathionine gamma-lyase [Dictyostelium discoideum AX4]
sp|Q55DV9|CGL_DICDI Cystathionine gamma-lyase (Gamma-cystathionase)
gb|EAL71911.1| cystathionine gamma-lyase [Dictyostelium discoideum AX4]
Length = 387
Score = 597 bits (1541), Expect = e-169, Method: Composition-based stats.
Identities = 147/404 (36%), Positives = 210/404 (51%), Gaps = 27/404 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
++ T V++ G D+++ +V P+ LSTTF YDYSRSGNPTR + I
Sbjct: 8 KIGTNVIHAGQSADKNTGAVIVPISLSTTFLQPSPGVLHSEYDYSRSGNPTRKAFEECIA 67
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ L+ +SG+ L I LL D +I+ DD+YGGT+R
Sbjct: 68 ACENA--KYALSFASGLATLTTITH---LLKSGDE----VISIDDVYGGTRRYFTRVAAN 118
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VD S + K F DK V +E+PTNPL KV DI + +V S T+
Sbjct: 119 FDLKFSFVDLSTLDDLKNAFT--DKTRLVWIETPTNPLLKVADIKAVADYVH--SRGATL 174
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VVDNT MS NPL L G D+V S TKY+NGH D + GV+ + E+ +KL F+ NS
Sbjct: 175 VVDNTFMSPYFQNPLDL--GADIVMHSVTKYINGHSDCVMGVLATNNDELYAKLKFLQNS 232
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA SP D +L +RGLKTL VR+ Q+NA + ++LE + K + + GL
Sbjct: 233 IGAVPSPFDCFLALRGLKTLHVRMEAHQKNAFAICNFLE--------KHPKVERVIYPGL 284
Query: 304 RSNPDFKLHKSFNNGPGAV-LSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPC 362
S+P ++ K G G + + F GS + S+ + + KL +A+ S G V SL+ +P
Sbjct: 285 PSHPQHEICKRQMKGYGGMVVFFVKGSIDQSRSFLENIKL--FALAESLGGVESLIELPS 342
Query: 363 KMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HAS+ E R + + L+RL GIE+I DL D+ A+
Sbjct: 343 VMTHASVPAEERAKLGISDTLIRLSVGIEDINDLLADISQALDK 386
>ref|ZP_01105937.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[Flavobacteriales bacterium HTCC2170]
gb|EAR03022.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[Flavobacteriales bacterium HTCC2170]
Length = 384
Score = 597 bits (1541), Expect = e-169, Method: Composition-based stats.
Identities = 126/402 (31%), Positives = 209/402 (51%), Gaps = 25/402 (6%)
Query: 5 RLDTVVVNTGSQNDQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ ++ ++ G Q D+ + A +PP+Y ++T+ + Y YSRS NPTR+ L++ +
Sbjct: 7 KFNSKTIHGGQQPDEAYGAVMPPIYQTSTYAQSTPGGH-KGYAYSRSANPTRTALENSLA 65
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ E LA +SG+ A+D +++ LL+ D ++A +D+YGG+ RL +
Sbjct: 66 SIEN--GEFGLAFASGLAAIDAVMK---LLSPGDE----VLATNDIYGGSYRLFKRVFEN 116
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
V VD + E+ K + LE+PTNP+ +VDI + + K V
Sbjct: 117 YGIVFHFVDMENPERITEHI--NTKTKLLWLETPTNPMMNIVDIKAVAQIAK--KHQLLV 172
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + PL L G D++ SATKYL GH D++ G ++ K +A +LYF+ N+
Sbjct: 173 AVDNTFATPYLQLPLDL--GADIIMHSATKYLGGHSDVVVGALVVKDKALADRLYFIQNA 230
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
+GA PMDS+L++RG+KTL VR+ + N +A +L + K K + G
Sbjct: 231 SGAVCGPMDSFLVLRGIKTLHVRMQRHCENGKAIAEYL--------AKHPKIDKVYWPGF 282
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P+ + K+ G ++SF ++ + ++L+I+ + S G V SL+ P
Sbjct: 283 ENHPNHSVAKTQMKDFGGMISFVPKGGDYQTSIKMVERLNIFTLAESLGGVESLVGHPAS 342
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
MSH+ I E R + + L+RL GIE+ DL DL A+
Sbjct: 343 MSHSGIPKEERVKAGVVDALIRLSVGIEDQADLIADLEQAIQ 384
>ref|ZP_00394699.1| COG0626: Cystathionine beta-lyases/cystathionine gamma-synthases
[Bacillus anthracis str. A2012]
Length = 377
Score = 597 bits (1541), Expect = e-169, Method: Composition-based stats.
Identities = 137/402 (34%), Positives = 220/402 (54%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I
Sbjct: 2 RAKTKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 61 VLEN--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VDT++ E+ + + K + +E+PTNPL K+ DI +I K
Sbjct: 112 FGIEHTFVDTTNLEEVEEAIRPNTK--AIYVETPTNPLLKITDIKKISTLAK--EKGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
++DNT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NS
Sbjct: 168 IIDNTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL
Sbjct: 226 TGGILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ + +L NG GA++SF+ S E +++ +L + + S G V SL+S+P +
Sbjct: 278 ASHQNHELATEQANGFGAIISFDVDSEETLNKVLE--RLQYFTLAESLGAVESLISIPSQ 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE + L+R+ GIE+ L +DL A+
Sbjct: 336 MTHASIPADRRKELGITDTLIRISVGIEDGEXLIEDLAQALA 377
>ref|ZP_01053161.1| Cystathionine gamma-synthase [Tenacibaculum sp. MED152]
gb|EAQ42589.1| Cystathionine gamma-synthase [Polaribacter dokdonensis MED152]
Length = 382
Score = 597 bits (1540), Expect = e-169, Method: Composition-based stats.
Identities = 134/401 (33%), Positives = 205/401 (51%), Gaps = 23/401 (5%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T ++ G +++ + SV PPV+L++TF E + Y Y+R NPTR+ L+
Sbjct: 2 KFNTKTIHGGQMHEETTGSVMPPVFLTSTFAQSSPGEH-KGYAYARGTNPTRTALEASFA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SGM A+D +LR LL D IIAGDDLYGGT R+ Q+
Sbjct: 61 ALENGT--HAFAFASGMAAIDAVLR---LLKPGDE----IIAGDDLYGGTYRMFTQLFQK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+VD + E + K + +E+PTNPL K+ DI I VK + + V
Sbjct: 112 YGLEFTYVDMNSIENVTYAITANTK--LIWIETPTNPLMKIADIEEISTKVKDENSEILV 169
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + PL L G D+V SATKYL GH DL+ G ++ ++A +++F+ +
Sbjct: 170 AVDNTFATPYLQKPLDL--GADIVMHSATKYLGGHSDLVMGALMVNNEKLAKEIHFIQFA 227
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA PMDS+L +RG+KTL VR+ + N + +A +L+ K K + GL
Sbjct: 228 AGAIAGPMDSFLALRGVKTLHVRMQRHCENGLKVAKFLDAHS--------KVGKVYYPGL 279
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++ + + K N G ++SF+ + ++ + S G V SL++ P
Sbjct: 280 ETHESYAIAKKQMNDFGGMVSFKLKDESQKATFAFLESTKLFTLAESLGGVESLVNHPVT 339
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
MSH SI + R + + L+RL GIE+I DL DL A+
Sbjct: 340 MSHGSIPEKERLKIGITDSLIRLSVGIEDIDDLLNDLEQAL 380
>ref|ZP_03949411.1| cystathionine gamma-synthase/cystathionine beta-lyase [Enterococcus
faecalis TX0104]
gb|EEI11151.1| cystathionine gamma-synthase/cystathionine beta-lyase [Enterococcus
faecalis TX0104]
Length = 394
Score = 596 bits (1539), Expect = e-168, Method: Composition-based stats.
Identities = 133/406 (32%), Positives = 203/406 (50%), Gaps = 27/406 (6%)
Query: 2 PIKRLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
+ +T +++ G D + +V P+Y ++TF+ + + + Y+YSRSGNPTR L+
Sbjct: 15 TFMKFNTKLIHGGISKDTTTGAVSVPIYQTSTFEQNGVGQ-PKEYEYSRSGNPTRHALET 73
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
I +L + A SSG+ + I+ + D+ I+ GDD+YGG+ RLL+
Sbjct: 74 LIAELEG--GSHGFAFSSGLAGIHAIIS---MFGPEDH----ILLGDDVYGGSFRLLDKV 124
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
+ V+ SD + Q K + LE+P+NPL K+ DI + K
Sbjct: 125 FVANGLSYTIVNASDLATIEAAIQPNTK--ALFLETPSNPLLKITDIEAAAKLAK--KHQ 180
Query: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
+VDNT + PL L G D+V S TKYL GH D++ G++++ PE A K+ F+
Sbjct: 181 LLTIVDNTFATPYFQRPLAL--GADIVVHSGTKYLGGHSDVVSGLVVTNHPESAEKIAFL 238
Query: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
N+ GA L P DSWL+ R LKTLGVR+ +NA +A +LE +
Sbjct: 239 QNAIGAVLGPHDSWLVQRSLKTLGVRMAAHAQNAQKIAEFLEAH--------PAVATVYY 290
Query: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
GL S+P ++ + +G ++SFE E V + L I+ + S G V SL+ +
Sbjct: 291 PGLASHPGHEIAQKQMSGFSGMISFELAKDEQVVPFVET--LEIFTLAESLGGVESLIEV 348
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
P M+HASI E R+ + L+RL GIE DL DL +
Sbjct: 349 PAIMTHASIPKENREAVGIKDGLIRLSVGIEADEDLLADLEKGLQA 394
>ref|YP_808806.1| cystathionine gamma-synthase/cystathionine beta-lyase [Lactococcus
lactis subsp. cremoris SK11]
gb|ABJ72384.1| cystathionine gamma-lyase [Lactococcus lactis subsp. cremoris SK11]
Length = 380
Score = 596 bits (1538), Expect = e-168, Method: Composition-based stats.
Identities = 141/405 (34%), Positives = 215/405 (53%), Gaps = 27/405 (6%)
Query: 3 IKRLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQ 61
+ L T V++ G D+ + +V P+Y ++T+K + + + Y+YSRSGNPTR L+
Sbjct: 1 MTSLKTKVIHGGISTDRTTGAVSVPIYQTSTYKQNGLGK-PKEYEYSRSGNPTRHALEEL 59
Query: 62 IGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFK 121
I L Q A SSG+ + +L L + D+ II DD+YGGT RL++
Sbjct: 60 IADLEGGVQ--GFAFSSGLAGIHAVLS---LFSAGDH----IILADDVYGGTFRLMDKVL 110
Query: 122 QQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDT 181
++ + VD S+ E K F++ K V E+P+NPL KV+DI I K + +
Sbjct: 111 TKTGIIYDLVDLSNLEDLKAAFKAETK--AVYFETPSNPLLKVLDIKEISSIAK--AHNA 166
Query: 182 TVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVI 241
+VDNT + P+ L G D+V SATKYL GH D++ G++ + + E+AS++ F+
Sbjct: 167 LTLVDNTFATPYLQQPIAL--GADIVLHSATKYLGGHSDVVAGLVTTNSNELASEIGFLQ 224
Query: 242 NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFV 301
NS GA L P DSWL+ RG+KTL +R+ NA +A +LE S +K +
Sbjct: 225 NSIGAVLGPQDSWLVQRGIKTLALRMEAHSANAQKIAEFLEASQA--------VSKVYYP 276
Query: 302 GLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
GL ++ ++ K G ++SFE K V + L + + S G V SL+ +P
Sbjct: 277 GLVNHEGHEIAKKQMTAFGGMISFELTDENAVKNFVEN--LRYFTLAESLGGVESLIEVP 334
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI ELR+E + L+RL G+E + DL DL A+
Sbjct: 335 AVMTHASIPKELREEIGIKDGLIRLSVGVEALEDLLTDLKEALEK 379
>emb|CAC05298.1| cystathionine beta-lyase [Lactobacillus reuteri]
Length = 380
Score = 596 bits (1537), Expect = e-168, Method: Composition-based stats.
Identities = 136/405 (33%), Positives = 206/405 (50%), Gaps = 27/405 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T +++ G+ D + +V P+Y S+TF + + + ++YSR+GNPTR L+ I
Sbjct: 2 KFNTQLIHGGNSEDPTTGAVSTPIYRSSTFHQHVLGGEPK-WEYSRTGNPTRVSLEKLIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+L A +SG A+ L + D+ + G D+YGGT RL+N ++
Sbjct: 61 ELEHGT--VGFAFASGSAAIHATFS---LFSQGDH----FVVGSDVYGGTFRLINKVLKR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VD D E + Q D V E+PTNPL ++ DI I K
Sbjct: 112 FGFEFTVVDMQDLEAVENAIQ--DNTVAVYFETPTNPLLQIADIKAIADIAK--KHGVKT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + N PL L G D+V SATKYL GH D++ G+ ++ EIA +L F+ NS
Sbjct: 168 IVDNTFATPYNQQPLTL--GADIVVHSATKYLGGHSDVVAGLAVTNDDEIAEQLAFLQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G+ L P DSWLL RG+KTLG R+ Q NA + ++L+N + K + GL
Sbjct: 226 IGSTLGPDDSWLLQRGMKTLGARMRVHQENANEVINFLQND--------DHIGKIYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+ P ++ GA++SFE +K+ V S L + + S G + SL+ +P
Sbjct: 278 KDFPGHEVAAKQMRNFGAMISFELKDSLDAKKFVES--LQLIDLAESLGGIESLIEVPAV 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+H SI E+R E ++L+RL GIE+ D+ DL A+ D
Sbjct: 336 MTHGSIPREIRLENGIKDELIRLSVGIEDPEDIIADLQQALKKLD 380
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|ZP_03970235.1| cystathionine gamma-lyase [Sphingobacter... 652 0.0
ref|ZP_02914409.1| Cystathionine gamma-synthase [Geobacillu... 646 0.0
ref|ZP_01062095.1| Cystathionine gamma-synthase [Flavobacte... 642 0.0
ref|YP_324649.1| Cys/Met metabolism pyridoxal-phosphate-dep... 640 0.0
ref|ZP_01886342.1| Cys/Met metabolism PLP-dependent enzyme ... 638 0.0
ref|YP_079997.1| cystathionine gamma-lyase YrhB [Bacillus l... 636 e-180
ref|ZP_02161506.1| Cys/Met metabolism PLP-dependent enzyme ... 636 e-180
ref|YP_001193064.1| Cystathionine gamma-lyase [Flavobacteri... 634 e-180
ref|ZP_01120255.1| Cys/Met metabolism PLP-dependent enzyme ... 633 e-179
ref|ZP_01733647.1| cystathionine gamma-lyase [Flavobacteria... 632 e-179
ref|YP_148393.1| cystathionine beta-lyase [Geobacillus kaus... 631 e-179
gb|AAW71993.1| cystathionine gamma-lyase [Macaca fascicularis] 631 e-179
ref|ZP_01173683.1| cystathionine beta-lyase [Bacillus sp. N... 631 e-179
sp|Q60HG7|CGL_MACFA Cystathionine gamma-lyase (Gamma-cystat... 631 e-179
ref|YP_001126563.1| cystathionine beta-lyase [Geobacillus t... 630 e-179
ref|YP_001295285.1| Cys/Met metabolism PLP-dependent enzyme... 630 e-179
ref|YP_630264.1| Cys/Met metabolism PLP-dependent enzyme [M... 630 e-179
ref|XP_537115.2| PREDICTED: similar to cystathionase isofor... 629 e-178
ref|YP_863450.1| Cys/Met metabolism pyridoxal-phosphate-dep... 628 e-178
ref|ZP_01689814.1| cystathionine gamma-synthase (CGS) (O-su... 628 e-178
emb|CAG01183.1| unnamed protein product [Tetraodon nigrovir... 628 e-178
ref|ZP_01719081.1| Cys/Met metabolism PLP-dependent enzyme ... 628 e-178
gb|AAX99219.1| cystathionine gamma-synthase [Helicobacter p... 628 e-178
dbj|BAB19922.2| cystathionine gamma-lyase [Rattus norvegicu... 626 e-178
ref|NP_206906.1| cystathionine gamma-synthase/cystathionine... 625 e-177
ref|XP_309478.3| AGAP011172-PA [Anopheles gambiae str. PEST... 625 e-177
ref|ZP_03983763.1| cystathionine gamma-synthase/cystathioni... 625 e-177
ref|YP_626847.1| cystathionine gamma-synthase/cystathionine... 625 e-177
ref|NP_001118157.1| cystathionine gamma-lyase inhibitor [On... 625 e-177
ref|NP_666065.1| cystathionase [Mus musculus] >gi|27734227|... 625 e-177
ref|XP_646022.1| cystathionine gamma-lyase [Dictyostelium d... 624 e-177
ref|YP_001487586.1| cystathionine beta-lyase [Bacillus pumi... 624 e-177
ref|ZP_00604875.1| Cystathionine gamma-synthase [Enterococc... 623 e-177
gb|EDL82568.1| cystathionase (cystathionine gamma-lyase) [R... 623 e-177
gb|AAH67624.1| Cth protein [Danio rerio] 623 e-176
ref|XP_001648394.1| cystathionine beta-lyase [Aedes aegypti... 623 e-176
ref|NP_997769.2| cystathionase (cystathionine gamma-lyase) ... 623 e-176
ref|ZP_01201479.1| cystathionine beta-lyase [Flavobacteria ... 622 e-176
ref|NP_266937.1| cystathionine gamma-synthase/cystathionine... 622 e-176
ref|YP_001909598.1| cystathionine gamma-synthase/cystathion... 621 e-176
ref|ZP_01053161.1| Cystathionine gamma-synthase [Tenacibacu... 621 e-176
ref|YP_002774266.1| cystathionine gamma-lyase [Brevibacillu... 621 e-176
ref|ZP_03949411.1| cystathionine gamma-synthase/cystathioni... 621 e-176
ref|YP_001381008.1| Cystathionine gamma-lyase [Anaeromyxoba... 621 e-176
ref|ZP_01909681.1| Cystathionine gamma-synthase [Plesiocyst... 621 e-176
ref|NP_834078.1| cystathionine beta-lyase [Bacillus cereus ... 621 e-176
ref|ZP_01890642.1| Cys/Met metabolism PLP-dependent enzyme ... 621 e-176
ref|ZP_02254620.1| cystathionine beta-lyase [Bacillus cereu... 620 e-176
ref|NP_814082.1| cystathionine gamma-synthase/cystathionine... 620 e-176
ref|ZP_03899337.1| cystathionine gamma-lyase [Dyadobacter f... 620 e-176
ref|NP_980747.1| cystathionine beta-lyase [Bacillus cereus ... 620 e-176
ref|ZP_02578916.1| cystathionine beta-lyase [Bacillus cereu... 620 e-176
ref|ZP_02187518.1| cystathionine gamma-lyase-like protein [... 620 e-176
ref|YP_085695.1| cystathionine beta-lyase [Bacillus cereus ... 620 e-176
ref|ZP_03982426.1| cystathionine gamma-synthase [Enterococc... 620 e-176
ref|NP_001087988.1| hypothetical protein LOC494673 [Xenopus... 620 e-175
ref|NP_846819.1| cystathionine beta-lyase [Bacillus anthrac... 620 e-175
ref|NP_824481.1| cystathionine gamma-synthase [Streptomyces... 620 e-175
ref|NP_011331.1| Cystathionine beta-lyase, converts cystath... 619 e-175
ref|NP_001038050.1| cystathionase [Sus scrofa] >gi|12214372... 619 e-175
ref|ZP_01105937.1| Cys/Met metabolism PLP-dependent enzyme ... 619 e-175
ref|YP_038423.1| cystathionine beta-lyase [Bacillus thuring... 619 e-175
ref|ZP_02175349.1| Cystathionine gamma-lyase [Anaeromyxobac... 619 e-175
ref|NP_643909.1| cystathionine gamma-lyase-like protein [Xa... 618 e-175
ref|ZP_00237381.1| trans-sulfuration enzyme family protein ... 618 e-175
ref|ZP_00741024.1| Cystathionine beta-lyase / Cystathionin... 618 e-175
ref|NP_989037.1| hypothetical protein LOC394634 [Xenopus tr... 618 e-175
ref|YP_001824091.1| putative cystathionine gamma-synthase [... 618 e-175
ref|YP_466910.1| cystathionine gamma-lyase [Anaeromyxobacte... 618 e-175
ref|YP_001270900.1| Cystathionine gamma-synthase [Lactobaci... 618 e-175
gb|ABO43784.1| cystathionine beta lyase [Lactobacillus reut... 618 e-175
ref|YP_331099.1| cystathionine synthase/lyase (cystathionin... 617 e-175
ref|NP_058770.1| CTL target antigen [Rattus norvegicus] >gi... 616 e-175
ref|XP_001844736.1| cystathionine beta-lyase [Culex pipiens... 616 e-174
ref|ZP_02845106.1| Cystathionine gamma-synthase [Paenibacil... 616 e-174
ref|ZP_02325786.1| Cystathionine gamma-lyase [Anaeromyxobac... 616 e-174
ref|XP_001634593.1| predicted protein [Nematostella vectens... 616 e-174
ref|ZP_00394699.1| COG0626: Cystathionine beta-lyases/cysta... 615 e-174
ref|YP_001376303.1| Cystathionine gamma-synthase [Bacillus ... 615 e-174
ref|YP_001647006.1| Cystathionine gamma-synthase [Bacillus ... 615 e-174
ref|YP_665187.1| cystathionine gamma-synthase/cystathionine... 615 e-174
ref|ZP_03816632.1| cystathionine gamma-lyase [Actinosynnema... 615 e-174
ref|ZP_02181558.1| Cystathionine gamma-synthase [Flavobacte... 615 e-174
ref|NP_390603.1| cystathionine beta-lyase [Bacillus subtili... 614 e-174
ref|YP_126280.1| hypothetical protein lpl0921 [Legionella p... 614 e-174
ref|NP_629110.1| cystathionine gamma-synthase [Streptomyces... 614 e-174
emb|CAC05298.1| cystathionine beta-lyase [Lactobacillus reu... 613 e-174
ref|YP_199417.1| cystathionine gamma-lyase-like protein [Xa... 613 e-174
ref|ZP_01049833.1| Cystathionine gamma-synthase [Cellulopha... 612 e-173
ref|ZP_01945763.1| putative O-succinylhomoserine (thiol)-ly... 612 e-173
ref|YP_808806.1| cystathionine gamma-synthase/cystathionine... 612 e-173
ref|ZP_01119325.1| Cystathionine gamma-synthase [Polaribact... 611 e-173
ref|ZP_02185683.1| cystathionine beta-lyase [Carnobacterium... 610 e-173
ref|YP_001345895.1| probable cystathionine gamma-lyase [Pse... 610 e-173
ref|ZP_03851922.1| cystathionine beta-lyase [Chryseobacteri... 610 e-173
ref|ZP_01859151.1| cystathionine beta-lyase [Bacillus sp. S... 610 e-173
ref|ZP_00972545.1| COG0626: Cystathionine beta-lyases/cysta... 610 e-173
ref|NP_820998.1| cystathionine beta-lyase [Coxiella burneti... 610 e-172
sp|P0C2T9|METC_LACLC Cystathionine beta-lyase (CBL) (Beta-c... 610 e-172
ref|ZP_01274696.1| Cystathionine gamma-synthase [Lactobacil... 609 e-172
ref|YP_001425430.1| putative O-succinylhomoserine (thiol)-l... 609 e-172
ref|ZP_02618072.1| cystathionine beta-lyase [Clostridium bo... 608 e-172
ref|ZP_03959522.1| cystathionine gamma-lyase [Lactobacillus... 608 e-172
gb|AAC45329.2| cystathionine gamma-lyase-like protein [Lact... 608 e-172
ref|NP_249091.1| probable cystathionine gamma-lyase [Pseudo... 608 e-172
ref|ZP_00967105.1| COG0626: Cystathionine beta-lyases/cysta... 608 e-172
ref|YP_001595952.1| putative O-succinylhomoserine (thiol)-l... 608 e-172
ref|ZP_02016714.1| Cystathionine gamma-synthase [Halorubrum... 608 e-172
ref|ZP_00949455.1| Cystathionine gamma-synthase [Croceibact... 608 e-172
ref|YP_001253267.1| cystathionine beta-lyase [Clostridium b... 607 e-172
ref|YP_001786093.1| cystathionine beta-lyase [Clostridium b... 607 e-172
ref|NP_970501.1| cystathionine gamma-lyase [Bdellovibrio ba... 607 e-172
ref|YP_001543285.1| Cystathionine gamma-synthase [Herpetosi... 606 e-172
ref|YP_121043.1| cystathionine gamma-synthase [Nocardia far... 606 e-171
ref|YP_001390087.1| cystathionine beta-lyase [Clostridium b... 606 e-171
ref|NP_222819.1| cystathionine beta-lyase [Helicobacter pyl... 606 e-171
ref|YP_001887506.1| cystathionine gamma-lyase [Clostridium ... 606 e-171
ref|YP_001477858.1| Cystathionine gamma-synthase [Serratia ... 606 e-171
ref|YP_001905157.1| Cys/Met metabolism PLP-dependent enzyme... 605 e-171
ref|ZP_03870765.1| cystathionine gamma-lyase [Halorhabdus u... 605 e-171
ref|ZP_02612783.1| cystathionine beta-lyase [Clostridium bo... 605 e-171
ref|ZP_02994313.1| hypothetical protein CLOSPO_01432 [Clost... 605 e-171
ref|NP_635990.1| cystathionine gamma-lyase-like protein [Xa... 604 e-171
ref|YP_001780368.1| cystathionine beta-lyase [Clostridium b... 604 e-171
gb|AAI51524.1| CTH protein [Bos taurus] 603 e-171
ref|YP_922185.1| Cystathionine gamma-synthase [Nocardioides... 603 e-170
ref|NP_001005400.1| cystathionase (cystathionine gamma-lyas... 603 e-170
ref|YP_002803098.1| cystathionine beta-lyase [Clostridium b... 603 e-170
ref|YP_001039191.1| Cystathionine gamma-synthase [Clostridi... 603 e-170
ref|NP_927875.1| hypothetical protein plu0523 [Photorhabdus... 603 e-170
ref|YP_001005776.1| putative cystathionine gamma-synthase [... 603 e-170
ref|YP_001103161.1| cystathionine gamma-synthase [Saccharop... 603 e-170
ref|YP_001814810.1| Cystathionine gamma-synthase [Exiguobac... 603 e-170
ref|YP_154611.1| Cystathionine gamma-synthase [Idiomarina l... 602 e-170
ref|ZP_03859526.1| cystathionine gamma-lyase [Kribbella fla... 601 e-170
ref|YP_348978.1| Cystathionine gamma-synthase [Pseudomonas ... 601 e-170
ref|ZP_04009503.1| cystathionine beta-lyase / cystathionine... 601 e-170
ref|NP_611352.1| Eip55E CG5345-PA [Drosophila melanogaster]... 601 e-170
ref|YP_002783098.1| cystathionine gamma-synthase/cystathion... 601 e-170
ref|NP_001019738.1| cystathionase [Bos taurus] >gi|75039975... 601 e-170
ref|ZP_01697151.1| Cys/Met metabolism pyridoxal-phosphate-d... 600 e-170
ref|YP_001843789.1| cystathionine beta-lyase [Lactobacillus... 600 e-170
ref|YP_430828.1| Cystathionine gamma-synthase [Moorella the... 599 e-169
ref|ZP_03945122.1| cystathionine gamma-synthase [Lactobacil... 599 e-169
ref|NP_001040113.1| cystathionine gamma-lyase [Bombyx mori]... 599 e-169
ref|YP_365456.1| Cys/Met metabolism PLP-dependent enzyme [X... 599 e-169
ref|YP_001394392.1| MetB1 [Clostridium kluyveri DSM 555] >g... 598 e-169
ref|YP_705780.1| cystathionine gamma-synthase [Rhodococcus ... 598 e-169
ref|ZP_00830322.1| COG0626: Cystathionine beta-lyases/cysta... 598 e-169
ref|YP_001133312.1| cystathionine gamma-synthase [Mycobacte... 598 e-169
gb|EEJ97771.1| cystathionine gamma-lyase [Thermomonospora c... 598 e-169
gb|EEJ80111.1| cystathionine gamma-lyase [Kangiella koreens... 598 e-169
ref|XP_513486.2| PREDICTED: cystathionase isoform 2 [Pan tr... 597 e-169
ref|NP_280068.1| MetB [Halobacterium sp. NRC-1] >gi|1692359... 597 e-169
gb|AAB86866.1| cystathionine gamma-lyase-like protein [Sten... 597 e-169
ref|NP_347030.1| Cystathionine gamma-synthase [Clostridium ... 597 e-169
gb|AAD17839.1| ecdysteroid-inducible polypeptide EIP40 [Dro... 597 e-169
ref|YP_383666.1| Cys/Met metabolism pyridoxal-phosphate-dep... 596 e-168
ref|YP_001512617.1| Cystathionine gamma-synthase [Alkaliphi... 596 e-168
pdb|2NMP|A Chain A, Crystal Structure Of Human Cystathionin... 596 e-168
ref|YP_549644.1| Cystathionine gamma-synthase [Polaromonas ... 596 e-168
ref|ZP_00590711.1| Cystathionine gamma-synthase [Pelodictyo... 596 e-168
gb|AAB24700.1| cystathionine gamma-lyase; cystathionase [Ho... 595 e-168
ref|NP_001893.2| cystathionase isoform 1 [Homo sapiens] >gi... 595 e-168
ref|YP_146720.1| cystathionine beta-lyase [Geobacillus kaus... 595 e-168
gb|AAP36257.1| Homo sapiens cystathionase (cystathionine ga... 595 e-168
dbj|BAB96807.1| probable cystathionine gamma-synthase [Rhod... 595 e-168
ref|YP_002754112.1| Cys/Met metabolism PLP-dependent enzyme... 595 e-168
ref|ZP_02244687.1| cystathionine gamma-lyase-like protein [... 595 e-168
ref|ZP_03999690.1| cystathionine gamma-lyase [Halogeometric... 595 e-168
ref|YP_534933.1| Cystathionine beta-lyase / Cystathionine g... 594 e-168
ref|YP_001360844.1| Cystathionine gamma-synthase [Kineococc... 594 e-168
ref|XP_422542.2| PREDICTED: similar to cystathionase [Gallu... 594 e-168
ref|XP_001601960.1| PREDICTED: similar to cystathionine gam... 594 e-168
ref|ZP_01853251.1| Cystathionine gamma-synthase [Planctomyc... 594 e-168
ref|YP_955451.1| cystathionine gamma-synthase [Mycobacteriu... 593 e-168
ref|YP_001422026.1| YrhB [Bacillus amyloliquefaciens FZB42]... 593 e-168
ref|ZP_01041902.1| Cystathionine gamma-synthase [Idiomarina... 593 e-168
ref|YP_641307.1| cystathionine gamma-synthase [Mycobacteriu... 593 e-168
ref|NP_147803.1| cystathionine gamma-lyase [Aeropyrum perni... 593 e-167
ref|ZP_03891390.1| cystathionine gamma-lyase [Geodermatophi... 593 e-167
ref|ZP_02913262.1| Cystathionine gamma-synthase [Geobacillu... 593 e-167
ref|YP_711051.1| cystathionine gamma-synthase, PLP-dependen... 593 e-167
ref|NP_215595.1| cystathionine gamma-synthase [Mycobacteriu... 593 e-167
ref|NP_347566.1| Cystathionine gamma-synthase [Clostridium ... 592 e-167
ref|ZP_03876613.1| cystathionine gamma-lyase [Haliangium oc... 592 e-167
ref|ZP_03831504.1| cystathionine gamma-synthase [Pectobacte... 592 e-167
ref|NP_738953.1| cystathionine gamma-synthase [Corynebacter... 591 e-167
ref|YP_446463.1| Cys/Met metabolism PLP-dependent enzyme su... 591 e-167
ref|NP_105358.1| cystathionine gamma-lyase [Mesorhizobium l... 591 e-167
ref|YP_901501.1| Cystathionine gamma-synthase [Pelobacter p... 591 e-167
ref|NP_692030.1| cystathionine beta-lyase [Oceanobacillus i... 590 e-167
ref|ZP_02840286.1| Cystathionine gamma-synthase [Arthrobact... 590 e-167
ref|YP_001708916.1| cystathionine gamma-synthase [Clavibact... 590 e-166
ref|YP_001037978.1| Cystathionine gamma-synthase [Clostridi... 590 e-166
ref|YP_001578047.1| Cystathionine beta-lyase [Lactobacillus... 589 e-166
ref|ZP_03941511.1| cystathionine gamma-synthase [Lactobacil... 588 e-166
ref|ZP_00996664.1| cystathionine gamma-synthase [Janibacter... 588 e-166
ref|ZP_03938504.1| cystathionine gamma-synthase [Lactobacil... 588 e-166
ref|YP_948740.1| cystathionine gamma-synthase [Arthrobacter... 588 e-166
emb|CAH89476.1| hypothetical protein [Pongo abelii] 588 e-166
ref|YP_001558344.1| Cystathionine gamma-synthase [Clostridi... 588 e-166
ref|YP_813202.1| Cystathionine beta-lyase/cystathionine gam... 587 e-166
ref|ZP_03807043.1| cystathionine beta-lyase [Lactobacillus ... 587 e-166
ref|NP_951998.1| cystathionine beta-lyase [Geobacter sulfur... 587 e-166
ref|XP_001014936.1| Cystathionine beta-lyase [Tetrahymena t... 586 e-166
ref|YP_001221613.1| cystathionine gamma-synthase [Clavibact... 586 e-165
ref|YP_001701939.1| Probable cystathionine gamma-synthase (... 586 e-165
ref|YP_001307772.1| Cystathionine gamma-synthase [Clostridi... 586 e-165
ref|NP_242494.1| cystathionine beta-lyase [Bacillus halodur... 585 e-165
ref|YP_001232580.1| Cystathionine gamma-synthase [Geobacter... 585 e-165
ref|YP_479490.1| Cystathionine gamma-synthase [Frankia sp. ... 585 e-165
ref|YP_619188.1| hypothetical protein Ldb1326 [Lactobacillu... 585 e-165
ref|YP_139336.1| cystathionine beta-lyase [Streptococcus th... 585 e-165
ref|NP_302550.1| cystathionine gamma-synthase [Mycobacteriu... 585 e-165
ref|ZP_01386815.1| Cystathionine gamma-synthase [Chlorobium... 585 e-165
ref|ZP_02950046.1| cystathionine gamma-synthase [Clostridiu... 585 e-165
ref|YP_820317.1| Cystathionine beta-lyase/cystathionine gam... 585 e-165
ref|YP_832540.1| cystathionine gamma-synthase [Arthrobacter... 585 e-165
ref|ZP_01593967.1| Cystathionine gamma-synthase [Geobacter ... 584 e-165
ref|YP_001438833.1| hypothetical protein ESA_02766 [Enterob... 584 e-165
ref|YP_141252.1| cystathionine beta-lyase [Streptococcus th... 583 e-165
ref|YP_811264.1| Cystathionine beta-lyase/cystathionine gam... 583 e-164
ref|NP_389070.1| cystathionine beta-lyase [Bacillus subtili... 583 e-164
gb|ABL09516.1| cystathionine beta-lyase [Halobacillus halop... 583 e-164
ref|YP_001251671.1| cystathionine beta-lyase [Legionella pn... 583 e-164
ref|YP_001616816.1| Cystathionine gamma-synthase [Sorangium... 583 e-164
ref|XP_001499357.1| PREDICTED: similar to cystathionase [Eq... 583 e-164
ref|YP_288501.1| cystathionine gamma-synthase [Thermobifida... 583 e-164
ref|YP_300343.1| cystathionine gamma-synthase [Staphylococc... 583 e-164
ref|YP_375448.1| Cystathionine gamma-synthase [Pelodictyon ... 583 e-164
ref|XP_001241519.1| hypothetical protein CIMG_08682 [Coccid... 582 e-164
ref|YP_001686522.1| Cystathionine gamma-lyase [Caulobacter ... 582 e-164
ref|XP_001481546.1| cystathionine beta-lyase MetG [Aspergil... 581 e-164
ref|NP_951999.1| cystathionine beta-lyase [Geobacter sulfur... 581 e-164
ref|ZP_02061867.1| cystathionine gamma-lyase (Gamma-cystath... 581 e-164
ref|NP_601644.1| cystathionine gamma-synthase [Corynebacter... 581 e-164
ref|ZP_01643667.1| Cystathionine gamma-synthase [Stenotroph... 580 e-164
ref|ZP_03955241.1| cystathionine gamma-lyase [Lactobacillus... 580 e-164
ref|XP_001678961.1| Hypothetical protein CBG24746 [Caenorha... 580 e-164
ref|YP_254463.1| cystathionine gamma-synthase [Staphylococc... 580 e-164
ref|XP_001848094.1| cystathionine gamma-lyase [Culex pipien... 580 e-164
ref|NP_765878.1| cystathionine gamma-synthase [Staphylococc... 580 e-164
ref|YP_094924.1| cystathionine beta-lyase [Legionella pneum... 579 e-163
ref|YP_001124871.1| cystathionine beta-lyase [Geobacillus t... 579 e-163
ref|NP_347031.1| Cystathionine beta-lyase [Clostridium acet... 579 e-163
ref|ZP_02732888.1| Cys/Met metabolism pyridoxal-phosphate-d... 578 e-163
ref|YP_001535772.1| Cystathionine gamma-synthase [Salinispo... 578 e-163
ref|XP_001262409.1| cystathionine beta-lyase MetG [Neosarto... 578 e-163
ref|YP_818758.1| Cystathionine beta-lyase/cystathionine gam... 578 e-163
ref|XP_001589290.1| hypothetical protein SS1G_09924 [Sclero... 578 e-163
ref|NP_859593.1| cystathionine gamma-synthase [Helicobacter... 578 e-163
ref|ZP_02916823.1| hypothetical protein BIFDEN_00082 [Bifid... 578 e-163
ref|ZP_03913719.1| cystathionine gamma-lyase [Leuconostoc m... 578 e-163
ref|NP_903719.1| cystathionine gamma-synthase [Chromobacter... 578 e-163
ref|YP_001157775.1| Cystathionine gamma-synthase [Salinispo... 578 e-163
ref|YP_591574.1| cystathionine gamma-lyase [Acidobacteria b... 578 e-163
ref|NP_495449.1| ZK1127.10 [Caenorhabditis elegans] >gi|170... 577 e-163
ref|YP_002761943.1| cystathionine beta-lyase [Gemmatimonas ... 576 e-163
ref|ZP_01389888.1| Cystathionine gamma-synthase [Geobacter ... 576 e-162
ref|YP_078488.1| putative Cystathionine beta-lyase [Bacillu... 576 e-162
ref|ZP_01389889.1| Cystathionine gamma-synthase [Geobacter ... 576 e-162
ref|YP_001321486.1| Cystathionine gamma-synthase [Alkaliphi... 576 e-162
ref|NP_959960.1| cystathionine gamma-synthase [Mycobacteriu... 576 e-162
ref|YP_001405148.1| Cystathionine gamma-lyase [Candidatus M... 576 e-162
ref|XP_001426097.1| hypothetical protein GSPATT00029327001 ... 576 e-162
gb|ACO15591.1| Cystathionine gamma-lyase [Caligus clemensi] 576 e-162
ref|YP_001307386.1| Cystathionine gamma-synthase [Clostridi... 576 e-162
ref|YP_520216.1| hypothetical protein DSY3983 [Desulfitobac... 576 e-162
gb|AAA64984.1| unknown [Pantoea agglomerans] 576 e-162
ref|XP_001825972.1| hypothetical protein [Aspergillus oryza... 574 e-162
ref|YP_889511.1| cystathionine gamma-synthase [Mycobacteriu... 574 e-162
gb|EDU44308.1| cystathionine beta-lyase [Pyrenophora tritic... 574 e-162
gb|ABG54358.1| cystathionine-gamma-lyase [Klebsiella pneumo... 574 e-162
ref|XP_001400722.1| hypothetical protein An14g00930 [Asperg... 574 e-162
ref|XP_001536920.1| cystathionine beta-lyase [Ajellomyces c... 574 e-162
ref|NP_507053.1| F22B8.6 [Caenorhabditis elegans] >gi|38762... 574 e-162
ref|YP_697502.1| cystathionine beta-lyase [Clostridium perf... 574 e-162
ref|YP_415909.1| cystathionine gamma-synthase [Staphylococc... 574 e-162
ref|XP_001750526.1| predicted protein [Monosiga brevicollis... 573 e-162
ref|ZP_00832333.1| COG0626: Cystathionine beta-lyases/cysta... 573 e-161
ref|YP_694633.1| cystathionine beta-lyase [Clostridium perf... 573 e-161
ref|YP_001420789.1| YjcJ [Bacillus amyloliquefaciens FZB42]... 573 e-161
ref|NP_373671.1| cystathionine gamma-synthase [Staphylococc... 573 e-161
ref|YP_002773358.1| cystathionine beta-lyase [Brevibacillus... 572 e-161
ref|ZP_01695913.1| Cys/Met metabolism pyridoxal-phosphate-d... 572 e-161
ref|ZP_01593966.1| Cystathionine gamma-synthase [Geobacter ... 572 e-161
ref|ZP_01371261.1| Cys/Met metabolism pyridoxal-phosphate-d... 572 e-161
ref|YP_002773359.1| cystathionine gamma-synthase/O-acetylho... 572 e-161
ref|YP_001232581.1| Cystathionine gamma-synthase [Geobacter... 571 e-161
ref|XP_757109.1| hypothetical protein UM00962.1 [Ustilago m... 571 e-161
ref|YP_185391.1| trans-sulfuration enzyme family protein [S... 571 e-161
ref|ZP_02635841.1| cystathionine beta-lyase [Clostridium pe... 571 e-161
ref|XP_452961.1| unnamed protein product [Kluyveromyces lac... 571 e-161
ref|YP_001337036.1| putative cystathionine gamma-synthase [... 571 e-161
ref|ZP_00824394.1| COG0626: Cystathionine beta-lyases/cysta... 571 e-161
ref|ZP_02963897.1| cystathionine gamma-synthase [Bifidobact... 571 e-161
ref|XP_972447.1| PREDICTED: similar to CG5345-PA [Tribolium... 570 e-161
ref|ZP_02631667.1| cystathionine beta-lyase [Clostridium pe... 570 e-161
ref|YP_901500.1| Cystathionine gamma-synthase [Pelobacter p... 570 e-160
Sequences not found previously or not previously below threshold:
>ref|ZP_03970235.1| cystathionine gamma-lyase [Sphingobacterium spiritivorum ATCC
33300]
gb|EEI90062.1| cystathionine gamma-lyase [Sphingobacterium spiritivorum ATCC
33300]
Length = 381
Score = 652 bits (1684), Expect = 0.0, Method: Composition-based stats.
Identities = 128/401 (31%), Positives = 202/401 (50%), Gaps = 25/401 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T ++ G Q+D + +V P+Y ++T++ + + ++YSR NPTR L+ +
Sbjct: 4 KFATKAIHAGQQSDPTTGAVMTPIYQTSTYQQASPGDH-KGFEYSRGTNPTRKALEDCLA 62
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L ++ LA +SGM A D +LR LL D ++ GDDLYGG+ R+ +Q
Sbjct: 63 ALEN--GKHGLAFASGMAATDCVLR---LLKPGDE----VVTGDDLYGGSYRIFTKVYEQ 113
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
V+TSD E + DK + +E+PTNP K+ DI I + K +
Sbjct: 114 YGITFKFVNTSDAEAVRAAIT--DKTKLIWVETPTNPTLKLADIEAIGQIAKTG--NALY 169
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VVDNT S NPL L G D+V SATKY+NGH D++ G +I E+ +L+F N+
Sbjct: 170 VVDNTFASPYLQNPLDL--GADIVMHSATKYINGHSDVVMGALILNDDELYKQLWFYYNA 227
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G P DS+L +RG+KTL +R+ N +A +L+N K + G
Sbjct: 228 CGGTPGPQDSFLALRGIKTLHLRMEAHCANGRKVAEFLKNH--------PKVETIYWPGF 279
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+P ++ K G ++S + + S + ++ + S G V SL++ P
Sbjct: 280 EDHPGHEIAKKQMRDFGGMISIVLKGADMQETFRISSRFKVFTLAESLGGVESLINHPAT 339
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+H SI E R++ ++L+RL GIE+ DL +DL A+
Sbjct: 340 MTHGSIPKEAREKVGVVDNLLRLSVGIEDADDLIEDLKQAL 380
>ref|ZP_02914409.1| Cystathionine gamma-synthase [Geobacillus sp. WCH70]
gb|EDT34473.1| Cystathionine gamma-synthase [Geobacillus sp. WCH70]
Length = 378
Score = 646 bits (1667), Expect = 0.0, Method: Composition-based stats.
Identities = 137/398 (34%), Positives = 217/398 (54%), Gaps = 27/398 (6%)
Query: 8 TVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLY 66
T +++ G D H+ +V P+Y +T+K + + ++YSR+GNPTR L+ I L
Sbjct: 5 TKLIHGGISGDPHTGAVSVPIYQVSTYKQEGIGGH-KGFEYSRTGNPTRHALEELIKDLE 63
Query: 67 RVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHA 126
A SSGM A+ ++ +L N D+ +I DD+YGGT R++ +
Sbjct: 64 E--GYAGFAFSSGMAAITAVM---MLFNSGDH----VILTDDVYGGTYRVMTKVLNRLGL 114
Query: 127 VSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVD 186
S +DTSD + Q K + +E+PTNPL K+ DI K +VD
Sbjct: 115 ESTFIDTSDLSNIEKHIQPNTK--ALYIETPTNPLLKITDIQAASAIAK--KHGLLTIVD 170
Query: 187 NTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGA 246
NT + P+ L G D+V SATKYL GH D++ G+ + + E+A KL+F+ NSTG
Sbjct: 171 NTFSTPYWQTPIAL--GADIVVHSATKYLGGHSDVVAGLAVVNSEELAEKLHFIQNSTGG 228
Query: 247 GLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSN 306
L P DSWLL+RG+KTLGVR+ + + N + +L N K + GL ++
Sbjct: 229 ILGPQDSWLLMRGIKTLGVRMEEHEENTRKIVEFLVNH--------PAVQKVYYPGLETH 280
Query: 307 PDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSH 366
P++++ K G G ++SF+ GS E + R+++ ++ + + S G V SL+S+P KM+H
Sbjct: 281 PNYEIAKKQMRGFGGMVSFDVGSAEKADRVLN--RVRYFTLAESLGAVESLISLPAKMTH 338
Query: 367 ASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
ASI E R++ + L+R+ G+E++ DL +DL A+
Sbjct: 339 ASIPKERREQLGITDGLIRISVGLEDVEDLLEDLAQAL 376
>ref|ZP_01062095.1| Cystathionine gamma-synthase [Flavobacterium sp. MED217]
gb|EAQ48224.1| Cystathionine gamma-synthase [Leeuwenhoekiella blandensis MED217]
Length = 380
Score = 642 bits (1658), Expect = 0.0, Method: Composition-based stats.
Identities = 129/405 (31%), Positives = 201/405 (49%), Gaps = 30/405 (7%)
Query: 5 RLDTVVVNTGSQN-DQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQI 62
+ +T ++ G N D + + +PP+Y ++T+ + ++YSRSGNPTR L+ +
Sbjct: 2 KFNTKTIHGGQHNTDPAYGSVMPPIYQTSTYAQSTPGGH-KGFEYSRSGNPTRKALEDAL 60
Query: 63 GKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQ 122
L + LA SG+ A+D +L+ L D II+ +DLYGG+ RL +
Sbjct: 61 ASLEN--GQFGLAFGSGLAAIDAVLK---LFKPGDE----IISTNDLYGGSYRLFTKIFE 111
Query: 123 QSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTT 182
V D + +K + +E+PTNP+ ++DI + +
Sbjct: 112 DFGLKFHFVSMQDTSAIEAAI--NEKTKMIWVETPTNPMMNIIDIEAVAQVA--TKHKIL 167
Query: 183 VVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
+ VDNT + PL L G D+V S TKYL GH DL+ G +I K E+A KLYF+ N
Sbjct: 168 LAVDNTFATPYLQQPLDL--GADLVMHSVTKYLGGHSDLVMGGLIVKDKELADKLYFIQN 225
Query: 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVG 302
++GA P DS+L +RG+KTL VR+ + N +A +L+ K + + G
Sbjct: 226 ASGAVCGPQDSFLALRGIKTLHVRMQRHCENGKAVAQFLKEH--------PKVDEVYWPG 277
Query: 303 LRSNPDFKLHKSFNNGPGAVLSFETG--SFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
+P+ ++ K G ++SF T S E + +V KL ++ + S G V SL
Sbjct: 278 FEEHPNHEIAKKQMKDFGGMVSFTTKKDSLEGAVEVVE--KLKVFTLAESLGGVESLAGH 335
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
P M+HASI E R++ + L+RL GIE+ DL DL A+
Sbjct: 336 PASMTHASIPKEERQKTGIKDSLIRLSVGIEDADDLLADLEQALA 380
>ref|YP_324649.1| Cys/Met metabolism pyridoxal-phosphate-dependent enzyme [Anabaena
variabilis ATCC 29413]
gb|ABA23754.1| cystathionine gamma-lyase [Anabaena variabilis ATCC 29413]
Length = 378
Score = 640 bits (1652), Expect = 0.0, Method: Composition-based stats.
Identities = 143/401 (35%), Positives = 223/401 (55%), Gaps = 28/401 (6%)
Query: 6 LDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGK 64
+T ++ G Q+D + +V P+YL++T++ + + + Y+YSR+GNPTR+ L+ +
Sbjct: 3 FETKAIHEGQQSDPQTGAVIVPIYLTSTYQQEAIGQH-KGYEYSRTGNPTRNALEEALAA 61
Query: 65 LYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQS 124
+ E LA +SG+ A +L LL D+ I+AGDDLYGGT RLL +
Sbjct: 62 IEN--GEYGLAFASGLAATTTVLS---LLKSCDH----IVAGDDLYGGTYRLLERVVKNW 112
Query: 125 HAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVV 184
+ +VD D F Q K + +E+PTNPL K++DI + + +V
Sbjct: 113 GVTTTYVDIDDISNFAKAIQPNTK--LIWVETPTNPLLKIIDIAALANIA--EQNNLILV 168
Query: 185 VDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINST 244
VDNT S PL G D+V S TKYL GH D++GG +++ ++ ++L F N+
Sbjct: 169 VDNTFASPYFQRPLD--NGADIVVHSTTKYLGGHSDIIGGAVVTSNEQLYTELKFYQNAI 226
Query: 245 GAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLR 304
GA SP DSWL++RG+KTL VR+ + ++NA++LA +LE K + + GL
Sbjct: 227 GAVPSPFDSWLVLRGIKTLAVRMREHEKNALLLAQFLEQH--------PKVERVYYPGLP 278
Query: 305 SNPDFKLHKSFNNGPGAVLSFET-GSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ +L KS +G G ++S E G F ++ + +L ++ + S G V SLL P K
Sbjct: 279 SHEQHQLAKSQMSGFGGMISLELKGDFADVEKF--ASRLQLFLLAESLGGVESLLCYPAK 336
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+H S+ E R +R ++LVRL GIEN++DL+ DL A+
Sbjct: 337 MTHGSLPQEERYKRGINDNLVRLSVGIENVLDLQADLENAL 377
>ref|ZP_01886342.1| Cys/Met metabolism PLP-dependent enzyme [Pedobacter sp. BAL39]
gb|EDM34452.1| Cys/Met metabolism PLP-dependent enzyme [Pedobacter sp. BAL39]
Length = 379
Score = 638 bits (1647), Expect = 0.0, Method: Composition-based stats.
Identities = 118/402 (29%), Positives = 198/402 (49%), Gaps = 25/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T ++ G + D + +V P+Y ++T+ ++ + ++YSR NPTR L+ +
Sbjct: 2 KFATKAIHAGQEPDPTTGAVMTPIYQTSTYWQKSPGDN-KGFEYSRGTNPTRKALEDCLA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + LA SSGM A D +++ LL D +I G+DLYGG+ R+ +
Sbjct: 61 ALENA--KYGLAFSSGMGATDAVMK---LLQPGDE----VITGNDLYGGSYRIFTKIYAK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+D S E DK V +E+PTNP +V+DI + + K +
Sbjct: 112 YGIKFHFIDLSKPENVLPYI--NDKTKLVWIETPTNPTMQVIDIEGVAKITKERK--LLL 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT S NP+ L G D+V S TKY+ GH D++ G ++ ++ L+F+ N+
Sbjct: 168 TVDNTFASPYLQNPMDL--GADIVMHSVTKYIGGHSDVVMGALLVNDDQLYKDLWFIYNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA P D++L++RG+KTL +R+ N +AH+L+N + K + G
Sbjct: 226 CGATPGPQDAFLVLRGIKTLHLRMKAHCENGEKVAHFLKNH--------PRIDKIYWPGF 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+P+ + K G G ++S + + + ++ + S G V SL++ P
Sbjct: 278 EDHPNHDIAKKQMRGFGGMVSITLKGADLQETFRIASSFKVFTLAESLGGVESLINHPTS 337
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+H SI E R++ ++L+RL G+E+I DL DL A+
Sbjct: 338 MTHGSIPKEEREKVGVTDNLLRLSVGVEDIDDLIADLEQALK 379
>ref|YP_079997.1| cystathionine gamma-lyase YrhB [Bacillus licheniformis ATCC 14580]
ref|YP_092416.1| cystathionine beta-lyase [Bacillus licheniformis ATCC 14580]
gb|AAU24359.1| cystathionine gamma-lyase YrhB [Bacillus licheniformis ATCC 14580]
gb|AAU41723.1| YrhB [Bacillus licheniformis DSM 13]
Length = 380
Score = 636 bits (1641), Expect = e-180, Method: Composition-based stats.
Identities = 136/402 (33%), Positives = 221/402 (54%), Gaps = 27/402 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T +++ G D+ + +V P+Y +T+K + Y+YSR+GNPTR+ L+ I
Sbjct: 2 KPKTKMIHGGITGDEKTGAVSVPIYQVSTYKQPRAGQH-TGYEYSRTGNPTRTALESLIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ A SGM A+ ++ +L D+ I+ DD+YGGT R++ +
Sbjct: 61 DVEG--GAAGYAFGSGMAAITAVM---MLFKSGDH----IVLTDDVYGGTYRVMTKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ DTS E + + K + +E+PTNPL K+ DI + K D +
Sbjct: 112 IGIEATFSDTSSIEDIEKAIKPNTK--AIYVETPTNPLLKITDIKKTAETAK--KHDLLL 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + NP+ L G D+V SATKYL GH D++GG++++ + E+A +++F+ NS
Sbjct: 168 IVDNTFYTPYFQNPISL--GADIVLHSATKYLGGHSDVVGGLVVAASKELAEEIHFIQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DSWLL+RG+KTLG+R+ ++NA +A +L++ K + GL
Sbjct: 226 TGGILGPQDSWLLMRGMKTLGLRMEAHEQNARKIAAFLDDH--------PAVKKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+P +L K + G G ++SF+ G E+ ++ +L + + S G V SL+S+P +
Sbjct: 278 PSHPGHELAKRQSTGFGGMISFDIGKEENVDLVLG--RLKWFTIAESLGAVESLISVPAR 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI PE R E + L+R+ G+E+I DL +DL A+
Sbjct: 336 MTHASIPPERRLELGITDGLIRISAGVEDIDDLLEDLQQALA 377
>ref|ZP_02161506.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein [Kordia
algicida OT-1]
gb|EDP96652.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein [Kordia
algicida OT-1]
Length = 383
Score = 636 bits (1641), Expect = e-180, Method: Composition-based stats.
Identities = 129/405 (31%), Positives = 207/405 (51%), Gaps = 29/405 (7%)
Query: 5 RLDTVVVNTGSQNDQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T ++ + D+ + A + P+Y ++T+ + Y+YSR+ NPTR+ L++ +
Sbjct: 2 KFNTKTIHGKQEPDKAYGAVMQPIYQTSTYAQSTPGGH-KGYEYSRTHNPTRNALENALA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ LA +SG+ A+D I++ LL D +I+ +DLYGGT RL +
Sbjct: 61 SIEN--GNYGLAFASGLAAIDAIIK---LLKPGDE----VISTNDLYGGTYRLFTRIFEG 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
V + K ++ K + +E+PTNP+ ++DI + K +
Sbjct: 112 FGIKFHFVGMENVAKIESYVNENTK--LIWVETPTNPMMNIIDIEAVSVIAK--KHQVML 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + PL L G D+V SATKY+ GH DL+ G +I EIA KLYF+ N+
Sbjct: 168 AVDNTFATPYLQRPLDL--GADIVMHSATKYIGGHSDLVMGALIVNDKEIADKLYFIQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
+GA PMDS+L +RG+KTL VR+ + N +A +L N K K + GL
Sbjct: 226 SGAICGPMDSFLALRGIKTLHVRMQRHCENGKAIAVYLANH--------PKIEKVYWPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSF--EHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
+++P+ + K + G ++SF E + ++V + L I+ + S G V SL P
Sbjct: 278 KNHPNHAIVKKQMDDFGGMISFVIKGNNYEEAIKIVEN--LKIFTLAESLGGVESLAGHP 335
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI E R++ + L+RL GIE++ DL DL A+
Sbjct: 336 ASMTHASIPKEEREKIGVVDALIRLSVGIEDVDDLIADLEQALSK 380
>ref|YP_001193064.1| Cystathionine gamma-lyase [Flavobacterium johnsoniae UW101]
gb|ABQ03745.1| cystathionine gamma-lyase [Flavobacterium johnsoniae UW101]
Length = 380
Score = 634 bits (1637), Expect = e-180, Method: Composition-based stats.
Identities = 137/402 (34%), Positives = 206/402 (51%), Gaps = 24/402 (5%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T V++ G +D + +V PPVY ++TF + +Y+YSR+ NPTR+ L+ +
Sbjct: 2 KFNTKVIHGGQHHDPSTGAVMPPVYQTSTFIQTSPGKPLADYEYSRASNPTRTALEEALA 61
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ LA SSG+ A D ILR D +IA DDLYGGT R+ + +
Sbjct: 62 SIENGT--RGLAFSSGLAATDCILRS---FKAGDE----VIAMDDLYGGTYRMFSRIYKD 112
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
S VD +D K K++ K V +E+PTNPL K+ DI + + K
Sbjct: 113 SGIKFHFVDMTDLAKLKSLINENTK--LVWVETPTNPLMKLADIAEVAKITK--EHKIWF 168
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + PL L G D+V SATKYL GH D++ G +I K + +L+F +
Sbjct: 169 AVDNTFATPYLQKPLDL--GADIVMHSATKYLGGHSDVIAGALIVKDEALGEQLHFQQFA 226
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TGA L PMDS+L++RG+KTL +R+ + N + +L K + + GL
Sbjct: 227 TGATLGPMDSFLVLRGIKTLALRVQRHCENGEKVVEYLSKH--------PKINRVYYPGL 278
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P ++ K G ++SF S + + +KL ++ + S G V SL + P
Sbjct: 279 ENHPFHEIAKKQMKAFGGMVSFTFKSGKKEDSIAFLEKLKVFTLAESLGGVESLANHPAL 338
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + R E +DLVRL GIE++ DL DL A+
Sbjct: 339 MTHASIPADKRAEVGITDDLVRLSVGIEDVEDLIADLEQALA 380
>ref|ZP_01120255.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[Robiginitalea biformata HTCC2501]
gb|EAR16783.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[Robiginitalea biformata HTCC2501]
Length = 388
Score = 633 bits (1633), Expect = e-179, Method: Composition-based stats.
Identities = 128/405 (31%), Positives = 206/405 (50%), Gaps = 29/405 (7%)
Query: 5 RLDTVVVNTGSQNDQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R ++ ++ G D+ + A +PP+Y ++T+ + Q Y+YSRSGNPTR L+ +
Sbjct: 6 RFNSRTIHGGQHPDKAYGAVMPPIYQTSTYAQSSPGQH-QGYEYSRSGNPTRHALEESLA 64
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ LA +SG+ A+D +++ LL D ++A +DLYGG+ RL +
Sbjct: 65 SIEN--GRFGLAFASGLAAMDAVVK---LLKPGDE----VLATNDLYGGSYRLFRKVFEP 115
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ D E + V +E+PTNP+ +V+DI + C S +
Sbjct: 116 LGIRFRFLGMQDAEAVASAIGPET--RLVWVETPTNPMMQVIDIAAVAE--SCRSRGVLL 171
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + PL+L G D+V SATKYL GH D++ G ++ K E+A +LYF+ N+
Sbjct: 172 AVDNTFATPYLQRPLEL--GADIVMHSATKYLGGHSDVVAGGLVVKDKELADRLYFIQNA 229
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
+GA PMDS+L++RG+KTL VR+ + N +A +L + + G
Sbjct: 230 SGAVCGPMDSFLVLRGIKTLHVRMQRHCENGRAVAEFLAGH--------PGVERVYWPGF 281
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGS--FEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
+P+ + G G ++SF FE + R+V + L ++ + S G V SL P
Sbjct: 282 PDHPNHDIAAKQMTGFGGMISFVPRGARFEDAVRIVEN--LRVFTLAESLGGVESLAGHP 339
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI + R++ + L+RL GIE+ DL +DL A+
Sbjct: 340 ASMTHASIPKDEREKSGVTDSLIRLSVGIEDAADLTEDLERALAA 384
>ref|ZP_01733647.1| cystathionine gamma-lyase [Flavobacteria bacterium BAL38]
gb|EAZ96716.1| cystathionine gamma-lyase [Flavobacteria bacterium BAL38]
Length = 381
Score = 632 bits (1631), Expect = e-179, Method: Composition-based stats.
Identities = 140/404 (34%), Positives = 213/404 (52%), Gaps = 28/404 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T ++ G +++ + +V PPV+ ++T+ + +Y+YSR+ NPTR+ L+ +
Sbjct: 2 KFNTKTIHGGQHHEKVTGAVMPPVFQTSTYVQSSPGKPVGDYEYSRAANPTRTALEDALA 61
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ LA SSG+ A D +LR + D IIA DDLYGGT RL +
Sbjct: 62 SIEN--GARGLAFSSGLAATDCLLR---MFKAGDE----IIAMDDLYGGTYRLFTRLYKD 112
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
S VD +D EKF+++ K V +E+PTNPL K+ DI I + K +
Sbjct: 113 SGIKFHFVDMNDLEKFQSLINENTK--LVWVETPTNPLMKLADIAAIAQITK--KHNILF 168
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + PL L G D+V SATKYL GH D++ G +I K + +L+F +
Sbjct: 169 AVDNTFATPYLQKPLDL--GADIVMHSATKYLGGHSDVIAGALIIKDKALGEELHFKQFA 226
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TGA L PMDS+L++RG+KTL +R+ + N +A +L+N + + GL
Sbjct: 227 TGATLGPMDSFLVLRGIKTLHLRVQRHCENGEKVAEYLDNHS--------LVERVYYPGL 278
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSF--EHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
S+P ++ K +G G +++F S E + + + L ++ + S G V SL + P
Sbjct: 279 ASHPFHEIAKKQMSGFGGMVTFTFKSGKKEDAIEFLEN--LKVFTLAESLGGVESLANHP 336
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
M+HASI + RKE +DLVRL GIE+I DL DL A
Sbjct: 337 ALMTHASIPEDKRKEVGISDDLVRLSVGIEDIEDLLADLEQAFK 380
>ref|YP_148393.1| cystathionine beta-lyase [Geobacillus kaustophilus HTA426]
dbj|BAD76825.1| cystathionine gamma-synthase [Geobacillus kaustophilus HTA426]
Length = 377
Score = 631 bits (1629), Expect = e-179, Method: Composition-based stats.
Identities = 135/398 (33%), Positives = 222/398 (55%), Gaps = 27/398 (6%)
Query: 8 TVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLY 66
T++++ G D H+ +V P+Y +T+K + + + ++YSR+GNPTR+ L+ I L
Sbjct: 5 TMLIHGGIPGDPHTGAVSVPIYQVSTYKQEEVGKH-KGFEYSRTGNPTRAALEKLIADLE 63
Query: 67 RVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHA 126
E A +SGM A+ ++ +L D+ ++ DD+YGGT R++ +
Sbjct: 64 G--GEAGFAFASGMAAITAVM---MLFQSGDH----LVLTDDVYGGTYRVMTNVLNRFGL 114
Query: 127 VSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVD 186
+ VDTSD + + K + +E+PTNPL K+ D+ + ++VD
Sbjct: 115 EATFVDTSDVANIEAHIRPNTK--AIYIETPTNPLLKITDLQA--AAAIARAHGLLLIVD 170
Query: 187 NTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGA 246
NT + PL+L G D+V SATKYL GH D++ G+ + +TPE+A +L++V NSTG
Sbjct: 171 NTFSTPYFQTPLEL--GADIVIHSATKYLGGHSDVVAGLAVVRTPELAERLHYVQNSTGG 228
Query: 247 GLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSN 306
L P DSWLL+RG+KTL VR+ + + NA +A +L + + GL +
Sbjct: 229 VLGPQDSWLLMRGMKTLAVRMEEHEENARQIAVFLAEHK--------AVKRVHYPGLPDH 280
Query: 307 PDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSH 366
P+ +L K G G ++SF+ GS E +++++S ++ + + S G V SL+S+P KM+H
Sbjct: 281 PNHELAKKQMRGFGGMISFDVGSLERAEKVLS--RVRYFTLAESLGAVESLISLPGKMTH 338
Query: 367 ASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
ASI E R++ + L+RL G+E++ DL DL A+
Sbjct: 339 ASIPKERREQLGITDGLIRLSVGLEDVNDLLDDLAKAL 376
>gb|AAW71993.1| cystathionine gamma-lyase [Macaca fascicularis]
Length = 405
Score = 631 bits (1629), Expect = e-179, Method: Composition-based stats.
Identities = 133/408 (32%), Positives = 203/408 (49%), Gaps = 28/408 (6%)
Query: 3 IKRLDTVVVNTGSQNDQHS--ASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
+ T ++ G + +Q + A VP + LSTTFK + + ++YSRSGNPTR+ L+
Sbjct: 15 FQHFATQAIHVGQEPEQWTSRAVVPLISLSTTFKQAAPGQHS-GFEYSRSGNPTRNCLEK 73
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
+ L + LA +SG+ A I LL D II DD+YGGT R
Sbjct: 74 AVAALDGA--KYCLAFASGLAATVTITH---LLKAGD----QIICMDDVYGGTNRYFRQV 124
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
+ VD S + + K V +E+PTNP+ K++DI V D
Sbjct: 125 ASEFGLKISFVDCSKIKLLEAAITPETK--LVWIETPTNPVLKMIDIEACAHIVHKRG-D 181
Query: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
+VVDNT MS PL L G D+ SATKY+NGH D++ G++ + ++L F+
Sbjct: 182 IILVVDNTFMSPYFQRPLAL--GADICMCSATKYMNGHSDVVMGLVSVNCERLHNRLRFL 239
Query: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
NS GA SP+D +L RGLKTL VR+ + +N M +A +LE++ K +
Sbjct: 240 QNSLGAVPSPLDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESN--------PGVEKVIY 291
Query: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGS-FEHSKRLVSSKKLSIWAVTVSFGCVNSLLS 359
GL S+P +L K G +++F +H++ + + L ++ + S G SL+
Sbjct: 292 PGLPSHPQHELAKRQCTGCTGMITFYIKGTLQHAEIFLKN--LKLFTLAESLGGFESLVE 349
Query: 360 MPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
+P M+HAS+ R + L+RL G+E+ DL +DL A+ A
Sbjct: 350 LPAIMTHASVPKNDRDVLGISDTLIRLSVGLEDEKDLLEDLDQALKAA 397
>ref|ZP_01173683.1| cystathionine beta-lyase [Bacillus sp. NRRL B-14911]
gb|EAR63626.1| cystathionine beta-lyase [Bacillus sp. NRRL B-14911]
Length = 378
Score = 631 bits (1629), Expect = e-179, Method: Composition-based stats.
Identities = 138/403 (34%), Positives = 219/403 (54%), Gaps = 27/403 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T +++ G D H+ +V P+Y +T+K + + ++YSR+GNPTR L+ I
Sbjct: 2 KRKTKLIHGGIAGDPHTGAVNIPIYQVSTYKQEGVGGH-KGFEYSRTGNPTRHALEELIK 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L E A SGM A+ ++ +L + D+ +I DD+YGGT R+++ +
Sbjct: 61 DLEG--GEAGFAFGSGMAAITAVM---MLFDSGDH----VIMTDDVYGGTYRVMSKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
S VDTS+ + + + K V LE+PTNPL K+ DI
Sbjct: 112 FGIESSFVDTSNLDNIEAEIKPNTK--AVYLETPTNPLLKITDIEG--AAAAAKKHGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + P+ L G D+V SATKY+ GH D++ G+++ + ++A L+FV NS
Sbjct: 168 IVDNTFSTPYWQTPISL--GADIVLHSATKYIGGHSDVVAGLVVVNSSKLAEDLHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DSWLL+RG+KTLGVR+ + + N + +L+N +K + G+
Sbjct: 226 TGGVLGPQDSWLLMRGIKTLGVRMEETEENTKAIVEFLQNH--------PAVSKVYYPGI 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+P+ ++ K G G ++SF+ GS E++ RL+S K+ + + S G V SL+S+P +
Sbjct: 278 ESHPNHEVAKKQAQGFGGMVSFDVGSEENADRLLS--KVKYFTLAESLGAVESLISVPAR 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI E R E + LVR+ G+E+ DL +DL A+
Sbjct: 336 MTHASIPAERRAELGITDGLVRISVGLEDSEDLIEDLKNALEK 378
>sp|Q60HG7|CGL_MACFA Cystathionine gamma-lyase (Gamma-cystathionase)
dbj|BAD51948.1| cystathionase [Macaca fascicularis]
Length = 405
Score = 631 bits (1628), Expect = e-179, Method: Composition-based stats.
Identities = 133/408 (32%), Positives = 203/408 (49%), Gaps = 28/408 (6%)
Query: 3 IKRLDTVVVNTGSQNDQHS--ASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
+ T ++ G + +Q + A VP + LSTTFK + + ++YSRSGNPTR+ L+
Sbjct: 15 FQHFATQAIHVGQEPEQWTSRAVVPLISLSTTFKQAAPGQHS-GFEYSRSGNPTRNCLEK 73
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
+ L + LA +SG+ A I LL D II DD+YGGT R
Sbjct: 74 AVAALDGA--KYCLAFASGLAATVTITH---LLKAGD----QIICMDDVYGGTNRYFRQV 124
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
+ VD S + + K V +E+PTNP+ K++DI V D
Sbjct: 125 ASEFGLKISFVDCSKIKLLEAAITPETK--LVWIETPTNPVLKMIDIEACAHIVHKRG-D 181
Query: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
+VVDNT MS PL L G D+ SATKY+NGH D++ G++ + ++L F+
Sbjct: 182 IILVVDNTFMSPYFQRPLAL--GADICMCSATKYMNGHSDVVMGLVSVNCERLHNRLRFL 239
Query: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
NS GA SP+D +L RGLKTL VR+ + +N M +A +LE++ K +
Sbjct: 240 QNSLGAVPSPLDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESN--------PGVEKVIY 291
Query: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGS-FEHSKRLVSSKKLSIWAVTVSFGCVNSLLS 359
GL S+P +L K G +++F +H++ + + L ++ + S G SL+
Sbjct: 292 PGLPSHPQHELAKRQCTGCTGMITFYIKGTLQHAEIFLKN--LKLFTLAESLGGFESLVE 349
Query: 360 MPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
+P M+HAS+ R + L+RL G+E+ DL +DL A+ A
Sbjct: 350 LPAIMTHASVPKNDRDVLGISDTLIRLSVGLEDEKDLLEDLDQALKAA 397
>ref|YP_001126563.1| cystathionine beta-lyase [Geobacillus thermodenitrificans NG80-2]
gb|ABO67818.1| Cystathionine gamma-lyase [Geobacillus thermodenitrificans NG80-2]
Length = 377
Score = 630 bits (1627), Expect = e-179, Method: Composition-based stats.
Identities = 138/398 (34%), Positives = 225/398 (56%), Gaps = 27/398 (6%)
Query: 8 TVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLY 66
T++++ G D H+ +V P+Y +T+K + + + ++YSR+GNPTR+ L+ I L
Sbjct: 5 TLLIHGGIPGDPHTGAVSVPIYQVSTYKQEEVGKH-KGFEYSRTGNPTRAALEKLIADLE 63
Query: 67 RVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHA 126
E A +SGM A+ ++ +L + D+ I+ DD+YGGT R++ +
Sbjct: 64 G--GEAGFAFASGMAAITAVM---MLFDSGDH----IVLTDDVYGGTYRVMANVLNRFGL 114
Query: 127 VSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVD 186
S VDTSD + + K + +E+PTNPL K+ D+ + ++VD
Sbjct: 115 ESTFVDTSDIANIEAHIRPNTK--AIYIETPTNPLLKITDLKA--AAAIARAHGLLLIVD 170
Query: 187 NTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGA 246
NT + PL+L G D+V SATKYL GH D++ G+ + +T E+A +L++V NSTG
Sbjct: 171 NTFSTPYFQTPLEL--GADIVIHSATKYLGGHSDVVAGLAVVRTAELAERLHYVQNSTGG 228
Query: 247 GLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSN 306
L P DSWLL+RG+KTLGVR+ + ++NA +A +L T+ + GL +
Sbjct: 229 ILGPQDSWLLMRGMKTLGVRMEEHEQNARAIAAFLAEHQ--------AVTRVYYPGLPEH 280
Query: 307 PDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSH 366
P+ +L K+ G G ++SF+ GS E ++ ++S ++ + + S G V SL+S+P KM+H
Sbjct: 281 PNHELAKAQMRGFGGMISFDVGSLERAETVLS--RVRYFTLAESLGAVESLISLPGKMTH 338
Query: 367 ASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
ASI E R++ + L+RL G+E++ DL DL A+
Sbjct: 339 ASIPKERREQLGITDGLIRLSVGLEDVNDLIDDLAQAL 376
>ref|YP_001295285.1| Cys/Met metabolism PLP-dependent enzyme [Flavobacterium
psychrophilum JIP02/86]
emb|CAL42467.1| Cys/Met metabolism PLP-dependent enzyme [Flavobacterium
psychrophilum JIP02/86]
Length = 382
Score = 630 bits (1626), Expect = e-179, Method: Composition-based stats.
Identities = 144/403 (35%), Positives = 211/403 (52%), Gaps = 26/403 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNED-AQNYDYSRSGNPTRSVLQHQI 62
+ +T V++ G +D + +V PPVY ++TF + +Y+YSR+ NPTRS L++ +
Sbjct: 2 KFNTKVIHGGQHHDPSTGAVMPPVYQTSTFVQTSPGQPLNPDYEYSRAANPTRSALENAL 61
Query: 63 GKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQ 122
+ LA SSG+ A D +LR D IIA DDLYGGT R+
Sbjct: 62 ASIENGT--RGLAFSSGLAATDCVLRS---FKAGDE----IIAMDDLYGGTYRMFTRIYA 112
Query: 123 QSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTT 182
S VD +D E F+++ K V +E+PTNPL K+ DI I + K
Sbjct: 113 NSGIKFHFVDMNDLENFESLINENTK--LVWVETPTNPLMKIADIAEIAKITK--KHKIL 168
Query: 183 VVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
VDNT + PL L G D+V SATKYL GH D++ G +I K E+ S+L+F
Sbjct: 169 FAVDNTFATPYLQKPLDL--GADIVMHSATKYLGGHSDVIAGALIVKDEELGSQLHFQQF 226
Query: 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVG 302
+TGA L PMDS+L++RG+KTL +R+ + N +A +L N K K + G
Sbjct: 227 ATGATLGPMDSFLVLRGIKTLHLRVQRHCENGAKVAEFLLNHS--------KIEKVYYPG 278
Query: 303 LRSNPDFKLHKSFN-NGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
L S+P + K G G +++F S + + + +K+ ++ + S G V SL + P
Sbjct: 279 LPSHPYHDIAKKQMIGGFGGMVTFTFKSGKKEEAISFLEKVKVFTLAESLGGVESLANHP 338
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+HASI + RKE +DLVRL G+E+ DL DL A+
Sbjct: 339 ALMTHASIPEDKRKEIGITDDLVRLSVGVEDAEDLIADLKQAL 381
>ref|YP_630264.1| Cys/Met metabolism PLP-dependent enzyme [Myxococcus xanthus DK
1622]
gb|ABF92425.1| Cys/Met metabolism PLP-dependent enzyme [Myxococcus xanthus DK
1622]
Length = 381
Score = 630 bits (1626), Expect = e-179, Method: Composition-based stats.
Identities = 135/406 (33%), Positives = 215/406 (52%), Gaps = 28/406 (6%)
Query: 5 RLDTVVVNTGSQNDQHSAS-VPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R DT+ ++ G + D + + + PVYL++T+ D E + Y+YSR+ NPTR LQ +
Sbjct: 2 RFDTLAIHAGQEPDPTTGAIMTPVYLTSTYVQDGPGEH-KGYEYSRTQNPTRKALQDCLA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SG+ D+++ +L+ D+ ++ DD+YGGT RL + ++
Sbjct: 61 ALEGA--KYGAAFASGLAGTDMLMH---MLDSGDH----VVVSDDVYGGTFRLFDKVFRR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ VD S E F+ K V +ESPTNP+ K++D+ RI K +
Sbjct: 112 AGLHFSFVDLSKPENFEAAITP--KTKMVWVESPTNPMLKLIDLARIAEVAK--KRNILS 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
V DNT M+ PL L G DVV S TKY+NGH D++GG + + ++A K+YF+ N+
Sbjct: 168 VADNTFMTPYFQRPLDL--GFDVVAHSTTKYINGHSDVVGGFVCTSREDVAEKMYFLQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G DS++++RG+KTL VR+ + NAM +A +L + K K + GL
Sbjct: 226 VGGVSGAFDSFMVLRGVKTLHVRMDRHASNAMKVAQFLASH--------PKVKKVTYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFET-GSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPC 362
++P L K +G G +++F+ G E ++ + + K ++A S G V SL+ P
Sbjct: 278 EAHPQHALAKQQMSGFGGMVTFDIQGGLEAARTFLKTVK--VFACAESLGGVESLIEHPA 335
Query: 363 KMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+HASI E R++ + +RL GIE+ DL DL A+ A
Sbjct: 336 IMTHASIPKETREQLGITDGFIRLSVGIEDARDLVDDLSQALDAAK 381
>ref|XP_537115.2| PREDICTED: similar to cystathionase isoform 1 [Canis familiaris]
Length = 405
Score = 629 bits (1623), Expect = e-178, Method: Composition-based stats.
Identities = 137/408 (33%), Positives = 201/408 (49%), Gaps = 28/408 (6%)
Query: 3 IKRLDTVVVNTGSQNDQHS--ASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
T ++ G + +Q S A VPP+ LSTTFK + A ++YSRSGNPTR+ L+
Sbjct: 15 FPHFATQAIHVGQEPEQWSSQAVVPPISLSTTFKQGAPGQHA-GFEYSRSGNPTRNCLEK 73
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
+ L + LA +SG+ A I LL D II DD+YGGT R
Sbjct: 74 AVAALDGA--KYSLAFASGLAATVTITH---LLKAGD----QIICMDDVYGGTNRYFRQV 124
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
+ VD S + + K V +E+PTNP K++DI V D
Sbjct: 125 ASEFGLKITFVDCSKIKLLEAAITPETK--LVWIETPTNPSLKMIDIEACAHTVHKRG-D 181
Query: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
+VVDNT MS PL L G D+ SATKY+NGH D++ G++ + + ++L F+
Sbjct: 182 IILVVDNTFMSAYFQRPLAL--GADICMYSATKYMNGHSDVVMGLVSVNSESLHNRLRFL 239
Query: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
NS GA SP+D +L RGLKTL VR+ + N M +A +LE++ + K +
Sbjct: 240 QNSIGAVPSPVDCYLCNRGLKTLHVRMEKHFENGMAVAQFLESN--------PRVEKVIY 291
Query: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGS-FEHSKRLVSSKKLSIWAVTVSFGCVNSLLS 359
GL S+P +L K G +++F H++ + K L ++ + S G SL
Sbjct: 292 PGLPSHPQHELAKRQCTGCPGMITFYIKGTLVHAEAFL--KHLKLFTLAESLGGYESLAE 349
Query: 360 MPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
+P M+HAS+ R + L+RL G+E+ DL +DL A+ A
Sbjct: 350 LPAIMTHASVPKSDRDVLGISDTLIRLSVGLEDKKDLLEDLDQALKAA 397
>ref|YP_863450.1| Cys/Met metabolism pyridoxal-phosphate-dependent enzyme [Gramella
forsetii KT0803]
emb|CAL68383.1| Cys/Met metabolism pyridoxal-phosphate-dependent enzyme [Gramella
forsetii KT0803]
Length = 380
Score = 628 bits (1622), Expect = e-178, Method: Composition-based stats.
Identities = 129/404 (31%), Positives = 207/404 (51%), Gaps = 30/404 (7%)
Query: 5 RLDTVVVNTGSQN-DQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQI 62
+ +T ++ G +N D + + +PP+Y +TT+ + ++YSRSGNPTR+ L+ +
Sbjct: 2 KFNTKTIHGGQENVDPAYGSVMPPIYQTTTYSQSTPGGH-KGFEYSRSGNPTRANLEKSL 60
Query: 63 GKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQ 122
L LA SG+ A+D +L+ L D II+ +DLYGG+ RL +
Sbjct: 61 ASLEN--GNFGLAFGSGLAAIDAVLK---LFKPGDE----IISTNDLYGGSYRLFTRIFE 111
Query: 123 QSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTT 182
V D E + K + +E+PTNP+ ++DI + + K D
Sbjct: 112 GLGIKFHFVGMQDAEGIEEYINENTK--LIWVETPTNPMMNIIDIAEVSKIAK--KHDLL 167
Query: 183 VVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
+ VDNT + PL L G D++ SATKYL GH D++ G ++ E+A KLYF+ N
Sbjct: 168 LAVDNTFATPYLQQPLGL--GADIIMHSATKYLGGHSDVVMGGLVVNDKELADKLYFIQN 225
Query: 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVG 302
++GA P DS+L++RG+KTL +R+ + N +A +L ++ K K + G
Sbjct: 226 ASGAICGPQDSFLVLRGIKTLHIRMQRHCENGAAVAKFLRSN--------PKVDKVYWPG 277
Query: 303 LRSNPDFKLHKSFNNGPGAVLSFETG--SFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
+P+ + + +G G ++SF T + E + ++V KL I+ + S G V SL
Sbjct: 278 FEDHPNHDIARKQMSGFGGMISFTTKANTLESATKIVE--KLKIFTLAESLGGVESLAGH 335
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
P M+HASI R++ + L+RL GIE+ DL DL A+
Sbjct: 336 PASMTHASIPKVDREKTGVVDSLIRLSVGIEDEEDLIADLSQAI 379
>ref|ZP_01689814.1| cystathionine gamma-synthase (CGS)
(O-succinylhomoserine(Thiol)-lyase) [Microscilla marina
ATCC 23134]
gb|EAY29195.1| cystathionine gamma-synthase (CGS)
(O-succinylhomoserine(Thiol)-lyase) [Microscilla marina
ATCC 23134]
Length = 387
Score = 628 bits (1622), Expect = e-178, Method: Composition-based stats.
Identities = 128/410 (31%), Positives = 212/410 (51%), Gaps = 28/410 (6%)
Query: 5 RLDTVVVNTGSQNDQHSAS-VPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T ++ G + + + + + P++ ++T+ + + Q Y+YSR+ NPTR+ L+ +
Sbjct: 2 KFGTKAIHAGVEPEPTTGAIMTPIFQTSTYVQEGLGKPRQGYEYSRTKNPTRTPLESNLA 61
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L ++ L +SGM+A D +++ L D IIA +D+YGGT RL+ +
Sbjct: 62 ALEN--GKHGLCFASGMSATDAVMKT---LKPGDE----IIACNDIYGGTYRLITKVYEP 112
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
V D + S K + E+PTNPL ++DI + + K + +
Sbjct: 113 LGLKPKFVAMGDLANVEAAITSNTK--LIWAETPTNPLLSIIDIAELAKVAK--KHNVLL 168
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + NPL L G D+V SATKYL GH D++ G +++ + E+ +L F+ NS
Sbjct: 169 CVDNTFATPYLQNPLDL--GADLVMHSATKYLGGHSDVVMGALVTSSDELHEQLAFIQNS 226
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA SP D +L++RG+KTL +R+ + + N +A +L N +K K ++GL
Sbjct: 227 CGAVPSPNDCFLMLRGIKTLHIRMDRHELNGKAVAEFLNNH--------DKVDKVYWIGL 278
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGS--FEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
S+ + K G G ++SF + +K+L+ S L ++A+ S G V SL + P
Sbjct: 279 PSHKGHDIVKKQMRGFGGMVSFTLKGNSMDEAKQLMES--LKVFALGESLGGVESLCTHP 336
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDADIIE 411
M+HASI E R+ R + L+RL GIE+ DL +DL A+ +
Sbjct: 337 ATMTHASIPEEEREARGLKQTLIRLSVGIEDADDLVEDLRQAIETITRVT 386
>emb|CAG01183.1| unnamed protein product [Tetraodon nigroviridis]
Length = 408
Score = 628 bits (1622), Expect = e-178, Method: Composition-based stats.
Identities = 137/408 (33%), Positives = 202/408 (49%), Gaps = 27/408 (6%)
Query: 3 IKRLDTVVVNTGSQNDQHS--ASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
K T ++ G + +Q + A VPP+ LSTTFK + A ++YSRSGNPTR+ L+
Sbjct: 20 FKSFATEAIHVGQEPEQWTSMAVVPPISLSTTFKQEEPGRHA-GFEYSRSGNPTRNCLEK 78
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
+ L + LA++SG+ A I +L D I+ DD+YGGT R
Sbjct: 79 AVAALDGA--KYCLALASGLAATVTITH---MLKAGD----GIVCMDDVYGGTNRYFQRV 129
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
D + E+ KT + K V +E+PTNP+ KVVDI S D
Sbjct: 130 ASNLGLEVSFADCTKPEQLKTALKPNTK--LVWIETPTNPMMKVVDIRVCSDLAHEHSKD 187
Query: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
VVVDNT MS PL L G D+ SATKY+NGH D++ G++ ++ KL F+
Sbjct: 188 IVVVVDNTFMSAYFQRPLAL--GADICMYSATKYMNGHSDVVMGLVSVNREDLYDKLKFL 245
Query: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
N+ G SP D +L RGLKTL +R+ + +NAM A +LE+ + + F
Sbjct: 246 QNALGGVPSPFDCYLCNRGLKTLHLRMERHFKNAMAAARFLES--------DPRVERVIF 297
Query: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGS-FEHSKRLVSSKKLSIWAVTVSFGCVNSLLS 359
GL S+P + K G +++F EH+ +S+ L ++ + S G SL
Sbjct: 298 PGLPSHPQHAVMKKQCTGCPGMITFYIKGKLEHASTFLSN--LKMFVIAESLGGYESLAE 355
Query: 360 MPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
P M+HAS+ R+ + L+RL G+E+ D+ +DL A+ A
Sbjct: 356 HPAIMTHASVPENERRVLGISDTLIRLSVGLEDEADIIRDLEQALAAA 403
>ref|ZP_01719081.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[Algoriphagus sp. PR1]
gb|EAZ80867.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[Algoriphagus sp. PR1]
Length = 381
Score = 628 bits (1621), Expect = e-178, Method: Composition-based stats.
Identities = 121/405 (29%), Positives = 204/405 (50%), Gaps = 29/405 (7%)
Query: 5 RLDTVVVNTGSQNDQHSAS-VPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T ++ G + D + + + P+Y ++T+ + Y+YSR+ NPTR+ LQ+ +
Sbjct: 2 KFGTKAIHAGVEPDPSTGAIMTPIYQTSTYVQRSPGDH-NGYEYSRTHNPTRTALQNNLA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L ++ + SSG+ A+D +++ L N D II+ +DLYGGT RL ++
Sbjct: 61 ALEN--GKHGICFSSGLGAIDAVVK---LFNPGDE----IISTNDLYGGTYRLFTKVFER 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
V D E +K + +E+PTNP+ ++D+ + + K + +
Sbjct: 112 YGIKFHFVPMGDPESITEYI--NEKTKMIWVETPTNPMMNIIDVAGVAKVAK--AHKVLL 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT S NPL G D+V S TKYL GH D++ G ++ EIA +L F+ N+
Sbjct: 168 AVDNTFASPYLQNPLD--QGADIVMHSVTKYLGGHSDVVMGALVLNDDEIADQLVFIQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA P D +L++RG+KTL +R+ + +N +A +L+ K K + G
Sbjct: 226 CGATPGPQDCFLVLRGIKTLHLRMERHSQNGKTIAAYLKTH--------PKVDKVYWPGF 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGS--FEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
+P+ + K G ++SF E + +++ + +L +A+ S G V SL P
Sbjct: 278 EDHPNHAIAKKQMRDFGGMISFTLVGNKQEDAVKVMENFQL--FALAESLGGVESLCGHP 335
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI E R++ + L+RL G+E+ DLK+DL A+
Sbjct: 336 ASMTHASIPKEEREKVGLVDSLIRLSVGVEDAEDLKQDLANALAK 380
>gb|AAX99219.1| cystathionine gamma-synthase [Helicobacter pylori]
Length = 380
Score = 628 bits (1620), Expect = e-178, Method: Composition-based stats.
Identities = 132/403 (32%), Positives = 205/403 (50%), Gaps = 27/403 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T +++ G D + +V P+Y ++T++ D + Y+YSRSGNPTR L+ I
Sbjct: 2 HMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIG-HHKGYEYSRSGNPTRFALEELIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SG+ + + LL D+ ++ GDD+YGGT RL N +
Sbjct: 61 DLEGGVK--GFAFASGLAGIHAVFS---LLQSGDH----VLLGDDVYGGTFRLFNKVLVK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +DTSD + K + K + LE+P+NPL K+ D+ + K
Sbjct: 112 NGLSCTIIDTSDLSQIKKAIKPNTK--ALYLETPSNPLLKITDLAQCASVAKD--HGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + NPL L G D+V S TKYL GH D++ G++ + +A ++ F N+
Sbjct: 168 IVDNTFATPYYQNPLLL--GADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G L P DSWLL RG+KTLG+R+ Q+NA+ +A +LE K + + GL
Sbjct: 226 IGGVLGPQDSWLLQRGIKTLGLRMQAHQKNALCVAEFLEKH--------PKVERVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P+++L K G +LSF + + V S L ++ + S G V SL+ +P
Sbjct: 278 PTHPNYELAKKQMRGFSGMLSFTLKNDSEATPFVES--LKLFILGESLGGVESLVGVPAF 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HA I R+ + LVRL GIE+ DL +DL A
Sbjct: 336 MTHACIPKTQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAK 378
>dbj|BAB19922.2| cystathionine gamma-lyase [Rattus norvegicus]
gb|AAK52091.1| cystathionine gamma-lyase [Rattus norvegicus]
gb|AAH78869.1| Cystathionase (cystathionine gamma-lyase) [Rattus norvegicus]
Length = 398
Score = 626 bits (1617), Expect = e-178, Method: Composition-based stats.
Identities = 134/409 (32%), Positives = 204/409 (49%), Gaps = 28/409 (6%)
Query: 2 PIKRLDTVVVNTGSQNDQHS--ASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQ 59
+ T ++ G + +Q S A V P+ L+TTFK D + + + YSRSGNPTR+ L+
Sbjct: 13 SFQHFATQAIHVGQEPEQWSSRAVVLPISLATTFKQDSPGQ-SSGFVYSRSGNPTRNCLE 71
Query: 60 HQIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNF 119
+ L ++ L +SG+ A I LL D +I D++YGGT R
Sbjct: 72 KAVAALDGA--KHCLTFASGLAATTTITH---LLKAGDE----VICMDEVYGGTNRYFRR 122
Query: 120 FKQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISP 179
+ VD S + + K V +E+PTNP K+ DI + V
Sbjct: 123 VASEFGLKISFVDCSKTKLLEAAITPQTK--LVWIETPTNPTLKLADIKACAQIVHKHK- 179
Query: 180 DTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYF 239
D +VVDNT MS PL L G D+ SATKY+NGH D++ G++ + ++ +L F
Sbjct: 180 DIILVVDNTFMSAYFQRPLAL--GADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRF 237
Query: 240 VINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTR 299
+ NS GA SP D +L RGLKTL +R+ + RN M +A +LE++ + K
Sbjct: 238 LQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESN--------PRVEKVI 289
Query: 300 FVGLRSNPDFKLHKSFNNGPGAVLSFETGS-FEHSKRLVSSKKLSIWAVTVSFGCVNSLL 358
+ GL S+P +L K G ++SF +H++ + + KL +A+ S G SL
Sbjct: 290 YPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLKNIKL--FALAESLGGYESLA 347
Query: 359 SMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
+P M+HAS+ + R + L+RL G+E+ DL +DL A+ A
Sbjct: 348 ELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQALKAA 396
>ref|NP_206906.1| cystathionine gamma-synthase/cystathionine beta-lyase [Helicobacter
pylori 26695]
sp|P56069|METB_HELPY Cystathionine gamma-synthase (CGS) (O-succinylhomoserine
(thiol)-lyase)
gb|AAD07176.1| cystathionine gamma-synthase (metB) [Helicobacter pylori 26695]
Length = 380
Score = 625 bits (1614), Expect = e-177, Method: Composition-based stats.
Identities = 133/405 (32%), Positives = 206/405 (50%), Gaps = 27/405 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R+ T +++ G D + +V P+Y ++T++ D + Y+YSRSGNPTR L+ I
Sbjct: 2 RMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRH-KGYEYSRSGNPTRFALEELIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SG+ + + LL D+ ++ GDD+YGGT RL N +
Sbjct: 61 DLEGGVK--GFAFASGLAGIHAVFS---LLQSGDH----VLLGDDVYGGTFRLFNQVLVK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +DTSD + K + K + LE+P+NPL K+ D+ + K
Sbjct: 112 NGLSCTIIDTSDISQIKKAIKPNTK--ALYLETPSNPLLKITDLAQCASVAKD--HGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + NPL L G D+V S TKYL GH D++ G++ + +A ++ F N+
Sbjct: 168 IVDNTFATPYYQNPLLL--GADIVAHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G L P DSWLL RG+KTLG+R+ Q+NA+ +A +LE K + + GL
Sbjct: 226 IGGVLGPQDSWLLQRGIKTLGLRMEAHQKNALCVAEFLEKH--------PKVERVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P+++L K G +LSF + + V S L ++ + S G V SL+ +P
Sbjct: 278 PTHPNYELAKKQMRGFSGMLSFTLKNDSEAVAFVES--LKLFILGESLGGVESLVGIPAF 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+HA I R+ + LVRL GIE+ DL +DL A
Sbjct: 336 MTHACIPKTQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG 380
>ref|XP_309478.3| AGAP011172-PA [Anopheles gambiae str. PEST]
gb|EAA05138.3| AGAP011172-PA [Anopheles gambiae str. PEST]
Length = 395
Score = 625 bits (1613), Expect = e-177, Method: Composition-based stats.
Identities = 138/407 (33%), Positives = 204/407 (50%), Gaps = 28/407 (6%)
Query: 4 KRLDTVVVNTGSQNDQHS--ASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQ 61
K T ++ G +Q + A VPP+ +STTFK + A ++Y RSGNPTR VL+
Sbjct: 14 KGFSTKAIHVGQDPEQWNSMAVVPPISMSTTFKQHGPGQHA-GFEYGRSGNPTRDVLERC 72
Query: 62 IGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFK 121
+ L L SSG+ A I+ +L D+ I+AGDDLYGGT RLL
Sbjct: 73 LASLDN--GRFGLTFSSGLGATTTII---TMLQNGDH----IVAGDDLYGGTNRLLRNVA 123
Query: 122 QQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDT 181
+ VD ++ + + + +E+PTNPL KVVDI + P
Sbjct: 124 LKMGIEVDFVDLTNMQLVEQAIKPNT--RLFWMETPTNPLLKVVDIRAVSEIAHKH-PGI 180
Query: 182 TVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVI 241
VVVDNT +S PL L G DVV S TKY+NGH D++ G +++ + +L F+
Sbjct: 181 VVVVDNTFLSSYLQRPLDL--GADVVMYSLTKYMNGHSDVIMGAMVTNDEAVYERLKFLQ 238
Query: 242 NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFV 301
N+ G SP D +L+ R LKTL +R+ + + N++ +A +LE K +
Sbjct: 239 NAAGIVPSPFDCYLVNRSLKTLALRMERHKSNSLAIARFLETH--------PKVERVLHP 290
Query: 302 GLRSNPDFKLHKSFNNGPGAVLSFET-GSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
GL S+P +L K G ++SF G E S + + L ++ + S G SL +
Sbjct: 291 GLPSHPQHELAKRQTYGHSGIMSFYIRGGLEESSNFLKA--LHVFTLAESLGGYESLAEL 348
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
P M+HAS+ + R+E + LVRL G+E++ DL DL A+ A
Sbjct: 349 PSVMTHASVPLQQRQELGITDGLVRLSVGLEDVDDLIADLQQALDKA 395
>ref|ZP_03983763.1| cystathionine gamma-synthase/cystathionine beta-lyase [Enterococcus
faecalis HH22]
gb|EEI58143.1| cystathionine gamma-synthase/cystathionine beta-lyase [Enterococcus
faecalis HH22]
Length = 394
Score = 625 bits (1613), Expect = e-177, Method: Composition-based stats.
Identities = 134/406 (33%), Positives = 205/406 (50%), Gaps = 27/406 (6%)
Query: 2 PIKRLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
P + +T +++ G D + +V P+Y ++TF+ + + + Y+YSRSGNPTR L+
Sbjct: 15 PFMKFNTKLIHGGISKDTTTGAVSVPIYQTSTFEQNGVGQ-PKEYEYSRSGNPTRHALET 73
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
I +L + A SSG+ + I+ + D+ I+ GDD+YGG+ RLL+
Sbjct: 74 LIAELEG--GSHGFAFSSGLAGIHAIIS---MFGPEDH----ILLGDDVYGGSFRLLDKV 124
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
+ V+ SD + Q K + LE+P+NPL K+ DI + K
Sbjct: 125 FVANGLSYTIVNASDLSTIEAAIQPNTK--ALFLETPSNPLLKITDIEAAAKLAK--KHQ 180
Query: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
+VDNT + PL L G D+V S TKYL GH D++ G++++ PE A K+ F+
Sbjct: 181 LLTIVDNTFATPYFQRPLAL--GADIVVHSGTKYLGGHSDVVSGLVVTNHPESAEKIAFL 238
Query: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
N+ GA L P DSWL+ R LKTLGVR+ +NA +A +LE +
Sbjct: 239 QNAIGAVLGPHDSWLVQRSLKTLGVRMAAHAQNAQKIAEFLEAH--------PAVATVYY 290
Query: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
GL S+P ++ + +G ++SFE E V + L I+ + S G V SL+ +
Sbjct: 291 PGLASHPGHEIAQKQMSGFSGMISFELAKDEQVVPFVEA--LEIFTLAESLGGVESLIEV 348
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
P M+HASI E R+ + L+RL GIE + DL DL +
Sbjct: 349 PAIMTHASIPKENREAVGIKDGLIRLSVGIEAVEDLLADLEKGLQA 394
>ref|YP_626847.1| cystathionine gamma-synthase/cystathionine beta-lyase [Helicobacter
pylori HPAG1]
gb|ABF84173.1| cystathionine gamma-synthase [Helicobacter pylori HPAG1]
Length = 380
Score = 625 bits (1612), Expect = e-177, Method: Composition-based stats.
Identities = 133/405 (32%), Positives = 207/405 (51%), Gaps = 27/405 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R+ T +++ G D + +V P+Y ++T++ D + Y+YSRSGNPTR L+ I
Sbjct: 2 RMQTKLIHGGISEDTTTGAVSVPIYQTSTYRQDAIG-HHKGYEYSRSGNPTRFALEELIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SG+ + + LL D+ ++ GDD+YGGT RL N +
Sbjct: 61 DLEGGVK--GFAFASGLAGIHAVFS---LLQSGDH----VLLGDDVYGGTFRLFNKVLVK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +DTSD + K + K + LE+P+NPL K+ D+ + K
Sbjct: 112 NGLSCTIIDTSDLSQIKKAIKQNTK--ALYLETPSNPLLKITDLAQCASVAKD--HGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + NPL L G D+V S TKYL GH D++ G++ + ++ ++ F N+
Sbjct: 168 IVDNTFATPYYQNPLLL--GADIVVHSGTKYLGGHSDVVAGLVTTNNEALSQEIAFFQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G L P DSWLL RG+KTL +R+ Q+NA+ +A +LE K K + GL
Sbjct: 226 IGGVLGPQDSWLLQRGIKTLALRMEAHQKNALCVAEFLEKH--------PKVEKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P+++L K+ G +LSF + + V S L ++ + S G V SL+ +P
Sbjct: 278 PTHPNYELAKAQMRGFSGMLSFTLKNDSEATLFVES--LKLFILGESLGGVESLVGIPAF 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+HA I E R+ + LVRL GIE+ DL +DL A
Sbjct: 336 MTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG 380
>ref|NP_001118157.1| cystathionine gamma-lyase inhibitor [Oncorhynchus mykiss]
gb|ABY40472.1| cystathionine gamma-lyase inhibitor [Oncorhynchus mykiss]
Length = 405
Score = 625 bits (1612), Expect = e-177, Method: Composition-based stats.
Identities = 139/408 (34%), Positives = 206/408 (50%), Gaps = 27/408 (6%)
Query: 3 IKRLDTVVVNTGSQNDQH--SASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
K T ++ G + +Q A VPP+ LSTTFK + A ++YSRSGNPTR+ L+
Sbjct: 18 FKSFATEAIHVGQEPEQWKSMAVVPPISLSTTFKQYRPGDHA-GFEYSRSGNPTRNCLEK 76
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
+ L ++ LA++SG+ A I +L D I+ +D+YGGT R
Sbjct: 77 AVAALDGA--KHCLALASGLAATMTISH---MLKAGD----GIVCMNDVYGGTNRYFRKI 127
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
+ V D + E + + K V +E+PTNP KVVDI V + D
Sbjct: 128 AAEVGLVVSFADCTKIELLQAALKPNTK--LVWIETPTNPTMKVVDIQACADVVHQHNTD 185
Query: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
T VVVDNT MS PL L G D+ SATKY+NGH D++ G++ ++ +L F+
Sbjct: 186 TVVVVDNTFMSAYFQRPLDL--GADICMYSATKYMNGHSDVVMGLVSVNNEDLYDRLKFL 243
Query: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
N+ GA SP D +L RGLKTL +R+ Q +NA+ +A +LE + + F
Sbjct: 244 QNALGAVPSPFDCYLCNRGLKTLHLRMRQHFKNALAVAKFLEA--------DPRVDRVIF 295
Query: 301 VGLRSNPDFKLHKSFNNGPGAVLSFET-GSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLS 359
GL S+P +L K G +++F G E++ +SS L ++A+ S G SL
Sbjct: 296 PGLPSHPQHELMKRQCTGCPGMITFYIEGKLENATTFLSS--LKMFALAESLGGYESLAE 353
Query: 360 MPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
P M+HAS+ R + L+RL G+E+ D+ +DL A+ A
Sbjct: 354 HPAIMTHASVPESDRAALGISDTLIRLSVGLEDEQDIIEDLEQALNAA 401
>ref|NP_666065.1| cystathionase [Mus musculus]
sp|Q8VCN5|CGL_MOUSE Cystathionine gamma-lyase (Gamma-cystathionase)
gb|AAH19483.1| Cystathionase (cystathionine gamma-lyase) [Mus musculus]
gb|AAL99218.1| cystathionine gamma-lyase [Mus musculus]
gb|AAP86975.1| cystathionine gamma-lyase [Mus musculus]
gb|EDL11858.1| cystathionase (cystathionine gamma-lyase) [Mus musculus]
Length = 398
Score = 625 bits (1612), Expect = e-177, Method: Composition-based stats.
Identities = 135/409 (33%), Positives = 206/409 (50%), Gaps = 28/409 (6%)
Query: 2 PIKRLDTVVVNTGSQNDQHS--ASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQ 59
+ T ++ G + +Q + A V P+ L+TTFK D + + ++YSRSGNPTR+ L+
Sbjct: 13 SFQHFATQAIHVGQEPEQWNSRAVVLPISLATTFKQDFPGQ-SSGFEYSRSGNPTRNCLE 71
Query: 60 HQIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNF 119
+ L ++ LA +SG+ A I LL D II D++YGGT R
Sbjct: 72 KAVAALDGA--KHSLAFASGLAATITITH---LLKAGDE----IICMDEVYGGTNRYFRR 122
Query: 120 FKQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISP 179
+ VD S + + K V +E+PTNP K+ DI + V
Sbjct: 123 VASEFGLKISFVDCSKTKLLEAAITPQTK--LVWIETPTNPTLKLADIGACAQIVHKRG- 179
Query: 180 DTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYF 239
D +VVDNT MS PL L G D+ SATKY+NGH D++ G++ + ++ S+L F
Sbjct: 180 DIILVVDNTFMSAYFQRPLAL--GADICMCSATKYMNGHSDVVMGLVSVNSDDLNSRLRF 237
Query: 240 VINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTR 299
+ NS GA SP D +L RGLKTL VR+ + +N M +A +LE + + K
Sbjct: 238 LQNSLGAVPSPFDCYLCCRGLKTLQVRMEKHFKNGMAVARFLETN--------PRVEKVV 289
Query: 300 FVGLRSNPDFKLHKSFNNGPGAVLSFETGS-FEHSKRLVSSKKLSIWAVTVSFGCVNSLL 358
+ GL S+P +L K +G ++SF +H+K + + L ++ + S G SL
Sbjct: 290 YPGLPSHPQHELAKRQCSGCPGMVSFYIKGALQHAKAFLKN--LKLFTLAESLGGYESLA 347
Query: 359 SMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
+P M+HAS+ + R + L+RL G+E+ DL +DL A+ A
Sbjct: 348 ELPAIMTHASVPEKDRATLGINDTLIRLSVGLEDEQDLLEDLDRALKAA 396
>ref|XP_646022.1| cystathionine gamma-lyase [Dictyostelium discoideum AX4]
sp|Q55DV9|CGL_DICDI Cystathionine gamma-lyase (Gamma-cystathionase)
gb|EAL71911.1| cystathionine gamma-lyase [Dictyostelium discoideum AX4]
Length = 387
Score = 624 bits (1611), Expect = e-177, Method: Composition-based stats.
Identities = 146/405 (36%), Positives = 208/405 (51%), Gaps = 27/405 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
++ T V++ G D+++ +V P+ LSTTF YDYSRSGNPTR + I
Sbjct: 8 KIGTNVIHAGQSADKNTGAVIVPISLSTTFLQPSPGVLHSEYDYSRSGNPTRKAFEECIA 67
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+ L+ +SG+ L I LL D +I+ DD+YGGT+R
Sbjct: 68 ACENA--KYALSFASGLATLTTITH---LLKSGDE----VISIDDVYGGTRRYFTRVAAN 118
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
VD S + K F DK V +E+PTNPL KV DI + +V T+
Sbjct: 119 FDLKFSFVDLSTLDDLKNAFT--DKTRLVWIETPTNPLLKVADIKAVADYVHS--RGATL 174
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VVDNT MS NPL L G D+V S TKY+NGH D + GV+ + E+ +KL F+ NS
Sbjct: 175 VVDNTFMSPYFQNPLDL--GADIVMHSVTKYINGHSDCVMGVLATNNDELYAKLKFLQNS 232
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA SP D +L +RGLKTL VR+ Q+NA + ++LE K + + GL
Sbjct: 233 IGAVPSPFDCFLALRGLKTLHVRMEAHQKNAFAICNFLEKH--------PKVERVIYPGL 284
Query: 304 RSNPDFKLHKSFNNGPGAV-LSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPC 362
S+P ++ K G G + + F GS + S+ + + KL +A+ S G V SL+ +P
Sbjct: 285 PSHPQHEICKRQMKGYGGMVVFFVKGSIDQSRSFLENIKL--FALAESLGGVESLIELPS 342
Query: 363 KMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
M+HAS+ E R + + L+RL GIE+I DL D+ A+
Sbjct: 343 VMTHASVPAEERAKLGISDTLIRLSVGIEDINDLLADISQALDKC 387
>ref|YP_001487586.1| cystathionine beta-lyase [Bacillus pumilus SAFR-032]
gb|ABV63026.1| cystathionine beta-lyase [Bacillus pumilus SAFR-032]
Length = 382
Score = 624 bits (1610), Expect = e-177, Method: Composition-based stats.
Identities = 141/403 (34%), Positives = 225/403 (55%), Gaps = 27/403 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T+++++G+ D+ + +V P+Y +T+K E Y+YSR+ NPTR+ L+ I
Sbjct: 2 KRKTMMIHSGTTGDEKTGAVSVPIYQVSTYKQPKAGEH-TGYEYSRTANPTRTALETAIR 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L N A SGM A+ ++ +L N D+ I+ DD+YGGT R++ +
Sbjct: 61 DLEG--GANGYAFGSGMAAITAVM---MLFNSGDH----IVLTDDVYGGTYRVITKVLNR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ VDTSD E K K V +ESPTNPL K+ D+ + + K + +
Sbjct: 112 IDIQATFVDTSDPEAVKKAILPETK--AVYIESPTNPLLKMTDLKAVGQLTK--EANILM 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + P++ G D+V SATKYL GH D++GG++++ T E+ +L+FV NS
Sbjct: 168 IVDNTFFTPYFQRPIE--YGADIVLHSATKYLGGHSDVVGGLVVTATEELGEELHFVQNS 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
TG L P DSWLL+RG+KTLG+R+ Q+NA +A +LE T+ + GL
Sbjct: 226 TGGILGPQDSWLLMRGIKTLGLRMEAHQQNAQKIAEFLEQH--------PAVTRVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P +L K+ +G G ++SF+ G EH +S +L ++ + S G V SL+S+P +
Sbjct: 278 DAHPGHELAKTQASGYGGMISFDIGKEEHVDVFLS--QLKLFTIAESLGAVESLISVPAR 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI + R+E + L+R+ GIE++ DL D+ +
Sbjct: 336 MTHASIPKDRREELGITDGLIRISVGIEDVDDLLNDMKQGLNA 378
>ref|ZP_00604875.1| Cystathionine gamma-synthase [Enterococcus faecium DO]
gb|EAN08794.1| Cystathionine gamma-synthase [Enterococcus faecium DO]
Length = 381
Score = 623 bits (1609), Expect = e-177, Method: Composition-based stats.
Identities = 130/405 (32%), Positives = 203/405 (50%), Gaps = 27/405 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ T +++ G D + +V P+Y ++T++ D + + Y+YSRSGNPTR L+ I
Sbjct: 2 HIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQ-PKQYEYSRSGNPTRFALEELIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L A SSG++ + + L D+ I+ GDD+YGGT RL + +
Sbjct: 61 DLEGGV--RGFAFSSGLSGIHAVFS---LFQAGDH----ILLGDDVYGGTFRLFDKVLTK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +DTS+ +K + + K + LE+P+NPL K+ D+ + V
Sbjct: 112 NGLEYTIIDTSNLDKIEQSIKPNTK--ALYLETPSNPLLKITDLEKSATLAH--QHGLIV 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+ DNT + PL L G D+V S TKYL GH D++ G++ S ++A ++ F N+
Sbjct: 168 IADNTFATPYFQRPLDL--GSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQIGFYQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA L P DSWLL RG+KTL VR+ + Q+NA ++A +L + K + GL
Sbjct: 226 IGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSH--------PAVEKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
+ + K +G ++SF + E + V S L ++ + S G V SL+ +P
Sbjct: 278 PDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVES--LQLFTLAESLGGVESLVEIPSV 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+HASI E R+E + L+RL GIE DL DL A
Sbjct: 336 MTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIK 380
>gb|EDL82568.1| cystathionase (cystathionine gamma-lyase) [Rattus norvegicus]
Length = 397
Score = 623 bits (1609), Expect = e-177, Method: Composition-based stats.
Identities = 133/406 (32%), Positives = 203/406 (50%), Gaps = 28/406 (6%)
Query: 2 PIKRLDTVVVNTGSQNDQHS--ASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQ 59
+ T ++ G + +Q S A V P+ L+TTFK D + + + YSRSGNPTR+ L+
Sbjct: 13 SFQHFATQAIHVGQEPEQWSSRAVVLPISLATTFKQDSPGQ-SSGFVYSRSGNPTRNCLE 71
Query: 60 HQIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNF 119
+ L ++ L +SG+ A I LL D +I D++YGGT R
Sbjct: 72 KAVAALDGA--KHCLTFASGLAATTTITH---LLKAGDE----VICMDEVYGGTNRYFRR 122
Query: 120 FKQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISP 179
+ VD S + + K V +E+PTNP K+ DI + V
Sbjct: 123 VASEFGLKISFVDCSKTKLLEAAITPQTK--LVWIETPTNPTLKLADIKACAQIVHKHK- 179
Query: 180 DTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYF 239
D +VVDNT MS PL L G D+ SATKY+NGH D++ G++ + ++ +L F
Sbjct: 180 DIILVVDNTFMSAYFQRPLAL--GADICMCSATKYMNGHSDVVMGLVSVNSDDLNERLRF 237
Query: 240 VINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTR 299
+ NS GA SP D +L RGLKTL +R+ + RN M +A +LE++ + K
Sbjct: 238 LQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESN--------PRVEKVI 289
Query: 300 FVGLRSNPDFKLHKSFNNGPGAVLSFETGS-FEHSKRLVSSKKLSIWAVTVSFGCVNSLL 358
+ GL S+P +L K G ++SF +H++ + + KL +A+ S G SL
Sbjct: 290 YPGLPSHPQHELAKRQCTGCPGMVSFYIKGTLQHAQVFLKNIKL--FALAESLGGYESLA 347
Query: 359 SMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
+P M+HAS+ + R + L+RL G+E+ DL +DL A+
Sbjct: 348 ELPAIMTHASVPEKDRATLGISDTLIRLSVGLEDEKDLLEDLGQAL 393
>gb|AAH67624.1| Cth protein [Danio rerio]
Length = 400
Score = 623 bits (1607), Expect = e-176, Method: Composition-based stats.
Identities = 144/407 (35%), Positives = 207/407 (50%), Gaps = 27/407 (6%)
Query: 4 KRLDTVVVNTGSQNDQHS--ASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQ 61
K T ++ GS+ +Q S A VPP+ LSTTFK + A ++YSRSGNPTR+ L+
Sbjct: 14 KSFATDAIHVGSEPEQWSSMAVVPPISLSTTFKQHGPGKHA-GFEYSRSGNPTRNCLEKA 72
Query: 62 IGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFK 121
+ L + LAV+SG+ A I L D I+ +D+YGGT R
Sbjct: 73 VAALDGA--KYCLAVASGLAATLTITH---LFKSGD----GILCMNDVYGGTNRYFRKVA 123
Query: 122 QQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDT 181
+ D + E+ K + K+ V +E+PTNP KVVDI V + DT
Sbjct: 124 SEVGLDISFADLTKLEELKAGLKPNTKM--VWIETPTNPTMKVVDIQACADIVHKHNKDT 181
Query: 182 TVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVI 241
VVVDNT MS PL L G D+ SATKY+NGH D++ G+I ++ +L F+
Sbjct: 182 IVVVDNTFMSAYFQRPLAL--GADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQ 239
Query: 242 NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFV 301
NS GA SP D ++ RGLKTL +R+ Q +NA+ A +LE + + F
Sbjct: 240 NSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEA--------DPRVDRVIFP 291
Query: 302 GLRSNPDFKLHKSFNNGPGAVLSFETGS-FEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
GL S+P +L K G +++F EH+ +S+ L ++A+ S G SL
Sbjct: 292 GLPSHPQHELTKRQCTGCPGMITFYIKGKLEHASTFLSN--LKLFALAESLGGYESLAEH 349
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
P M+HAS+ E RK+ + L+RL G+E+ D+ DL A+ A
Sbjct: 350 PAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALSAA 396
>ref|XP_001648394.1| cystathionine beta-lyase [Aedes aegypti]
gb|EAT44603.1| cystathionine beta-lyase [Aedes aegypti]
Length = 403
Score = 623 bits (1607), Expect = e-176, Method: Composition-based stats.
Identities = 139/407 (34%), Positives = 204/407 (50%), Gaps = 28/407 (6%)
Query: 4 KRLDTVVVNTGSQNDQH--SASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQ 61
K T ++ G +Q A VPP+ +STTFK + A Y+Y RSGNPTR VL+
Sbjct: 22 KGFATKAIHVGQDAEQWKSRAVVPPISMSTTFKQFGPAQHA-GYEYGRSGNPTRDVLERC 80
Query: 62 IGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFK 121
+ L + L SSG+ ++ +L+ D+ I+AGDDLYGGT RLL
Sbjct: 81 LASLDN--GKYGLTFSSGLGVTTTVI---TMLSAGDH----IVAGDDLYGGTNRLLRKVA 131
Query: 122 QQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDT 181
+ + VD +D K + + K +E+PTNPL KV+DI + P
Sbjct: 132 MKMNIEVDFVDCTDLAKVEAAVKPNTK--LFWIETPTNPLLKVIDIEAVSEVAHKF-PGV 188
Query: 182 TVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVI 241
VVVDNT +S PL L G D+V S TKY+NGH D++ G I + +L F+
Sbjct: 189 VVVVDNTFLSAYLQRPLDL--GADIVMYSLTKYMNGHSDVIMGAAIMNDEALYEQLKFLQ 246
Query: 242 NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFV 301
N+ G SP D +L+ R LKTL +R+ + + N++ +A +LE K +
Sbjct: 247 NAAGIVPSPFDCYLVNRSLKTLALRMERHKSNSLAIAKFLEKH--------PKVERVLHP 298
Query: 302 GLRSNPDFKLHKSFNNGPGAVLSFET-GSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
GL S+P +L K G ++SF G E S + + S L ++ + S G SL +
Sbjct: 299 GLPSHPQHELAKKQTYGHSGIMSFYIKGGMEESTKFLQS--LEVFTLAESLGGYESLAEV 356
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
P M+HAS+ PE R ++L+R+ G+E+ DL DL A+ A
Sbjct: 357 PSVMTHASVPPEHRALLGITDNLIRISVGLEDADDLIVDLKQALEKA 403
>ref|NP_997769.2| cystathionase (cystathionine gamma-lyase) [Danio rerio]
gb|AAH56538.1| Cystathionase (cystathionine gamma-lyase) [Danio rerio]
Length = 400
Score = 623 bits (1607), Expect = e-176, Method: Composition-based stats.
Identities = 144/407 (35%), Positives = 207/407 (50%), Gaps = 27/407 (6%)
Query: 4 KRLDTVVVNTGSQNDQHS--ASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQ 61
K T ++ GS+ +Q S A VPP+ LSTTFK + A ++YSRSGNPTR+ L+
Sbjct: 14 KSFATDAIHVGSEPEQWSSMAVVPPISLSTTFKQHGPGKHA-GFEYSRSGNPTRNCLEKA 72
Query: 62 IGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFK 121
+ L + LAV+SG+ A I L D I+ +D+YGGT R
Sbjct: 73 VAALDGA--KYCLAVASGLAATLTITH---LFKSGD----GILCMNDVYGGTNRYFRKVA 123
Query: 122 QQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDT 181
+ D + E+ K + K+ V +E+PTNP KVVDI V + DT
Sbjct: 124 SEVGLDISFADLTKLEELKAGLKPNTKM--VWIETPTNPTMKVVDIQACADIVHKHNKDT 181
Query: 182 TVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVI 241
VVVDNT MS PL L G D+ SATKY+NGH D++ G+I ++ +L F+
Sbjct: 182 IVVVDNTFMSAYFQRPLAL--GADICMYSATKYMNGHSDVVMGLISLSRDDLYERLKFLQ 239
Query: 242 NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFV 301
NS GA SP D ++ RGLKTL +R+ Q +NA+ A +LE + + F
Sbjct: 240 NSLGAVPSPFDCYMCNRGLKTLHLRMKQHFKNALAAAQFLEA--------DPRVDRVIFP 291
Query: 302 GLRSNPDFKLHKSFNNGPGAVLSFETGS-FEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
GL S+P +L K G +++F EH+ +S+ L ++A+ S G SL
Sbjct: 292 GLPSHPQHELTKRQCTGCPGMITFYIKGKLEHASTFLSN--LKLFALAESLGGYESLAEH 349
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDA 407
P M+HAS+ E RK+ + L+RL G+E+ D+ DL A+ A
Sbjct: 350 PAIMTHASVCEEERKKLGISDTLIRLSVGLEDEEDIIADLDQALGAA 396
>ref|ZP_01201479.1| cystathionine beta-lyase [Flavobacteria bacterium BBFL7]
gb|EAS20897.1| cystathionine beta-lyase [Flavobacteria bacterium BBFL7]
Length = 386
Score = 622 bits (1606), Expect = e-176, Method: Composition-based stats.
Identities = 127/404 (31%), Positives = 206/404 (50%), Gaps = 30/404 (7%)
Query: 5 RLDTVVVNTGSQN-DQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQI 62
+ +T ++ G +N D +++ +PP+Y +TTFK + + ++YSRSGNPTR L+ +
Sbjct: 7 KFNTKAIHGGQENIDPAYNSVMPPIYQTTTFKQSTPHGH-KGFEYSRSGNPTRDALEKSM 65
Query: 63 GKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQ 122
L +A SG+ A+D +L+ LL D +I+ DLYGG+ RL Q
Sbjct: 66 ASLEN--GAYGIAFGSGLAAIDAVLK---LLKSGDE----VISTSDLYGGSYRLFTQIFQ 116
Query: 123 QSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTT 182
+ + + + K + +E+PTNP+ ++DI I +
Sbjct: 117 DFGIKFHFIGMENADNIEKHINKNTK--LLWVETPTNPMMNIIDIEAISKI--SNKHQLI 172
Query: 183 VVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
+ VDNT + PL L G D+V SATKYL GH D++ G ++ +A +LYF+ N
Sbjct: 173 LAVDNTFATPYLQQPLDL--GADIVMHSATKYLGGHSDVVMGSLVLNNEALAKRLYFIQN 230
Query: 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVG 302
++GA P D +L++RG+KTL VR+ + N +AH L ++ + + G
Sbjct: 231 ASGAVPGPQDCFLVLRGIKTLHVRMQRHCENGKAVAHALRSN--------PYVDQVYWPG 282
Query: 303 LRSNPDFKLHKSFNNGPGAVLSFET--GSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
S+P+ + K G ++SF T G+ E + ++V S L ++ + S G V SL
Sbjct: 283 FESHPNHVIAKKQMKDYGGMVSFSTKAGTLESAVKVVES--LKVFTLGESLGGVESLAGH 340
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
P M+HASI E R++ + L+RL GIE++ DL DL A+
Sbjct: 341 PASMTHASIPKEDREKTGVVDSLIRLSVGIEDVDDLITDLEQAL 384
>ref|NP_266937.1| cystathionine gamma-synthase/cystathionine beta-lyase [Lactococcus
lactis subsp. lactis Il1403]
ref|YP_001033049.1| cystathionine gamma-synthase/cystathionine beta-lyase [Lactococcus
lactis subsp. cremoris MG1363]
sp|P0A4K2|METC_LACLA Cystathionine beta-lyase (CBL) (Beta-cystathionase) (Cysteine
lyase)
sp|A2RM21|METC_LACLM Cystathionine beta-lyase (CBL) (Beta-cystathionase) (Cysteine
lyase)
gb|AAF14693.1|AF131880_1 cystathionine beta-lyase MetC [Lactococcus lactis subsp. cremoris]
gb|AAF36088.1|AF170901_1 cystathionine beta/gamma-lyase [Lactococcus lactis subsp. cremoris]
gb|AAK04879.1|AE006311_10 cystathionine gamma-synthase (EC 4.2.99.9) [Lactococcus lactis
subsp. lactis Il1403]
emb|CAL98348.1| cystathionine beta-lyase [Lactococcus lactis subsp. cremoris
MG1363]
Length = 380
Score = 622 bits (1606), Expect = e-176, Method: Composition-based stats.
Identities = 141/405 (34%), Positives = 216/405 (53%), Gaps = 27/405 (6%)
Query: 3 IKRLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQ 61
+ + T V++ G D+ + +V P+Y ++T+K + + + Y+YSRSGNPTR L+
Sbjct: 1 MTSIKTKVIHGGISTDKTTGAVSVPIYQTSTYKQNGLGQ-PKEYEYSRSGNPTRHALEEL 59
Query: 62 IGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFK 121
I L A SSG+ + +L L + D+ II DD+YGGT RL++
Sbjct: 60 IADLEGGV--QGFAFSSGLAGIHAVLS---LFSAGDH----IILADDVYGGTFRLMDKVL 110
Query: 122 QQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDT 181
++ + VD S+ + K F+ K + E+P+NPL KV+DI I K + D
Sbjct: 111 TKTGIIYDLVDLSNLDDLKAAFKEETK--AIYFETPSNPLLKVLDIKEISAIAK--AHDA 166
Query: 182 TVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVI 241
+VDNT + P+ L G D+V SATKYL GH D++ G++ + + E+AS++ F+
Sbjct: 167 LTLVDNTFATPYLQQPIAL--GADIVLHSATKYLGGHSDVVAGLVTTNSKELASEIGFLQ 224
Query: 242 NSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFV 301
NS GA L P DSWL+ RG+KTL +R+ NA +A +LE S +K +
Sbjct: 225 NSIGAVLGPQDSWLVQRGIKTLALRMEAHSANAQKIAEFLETSK--------AVSKVYYP 276
Query: 302 GLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
GL S+P ++ K + G ++SFE K V + LS + + S G V SL+ +P
Sbjct: 277 GLNSHPGHEIAKKQMSAFGGMISFELTDENAVKDFVEN--LSYFTLAESLGGVESLIEVP 334
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI ELR+E + L+RL G+E I DL D+ A+
Sbjct: 335 AVMTHASIPKELREEIGIKDGLIRLSVGVEAIEDLLTDIKEALEK 379
>ref|YP_001909598.1| cystathionine gamma-synthase/cystathionine beta-lyase [Helicobacter
pylori Shi470]
gb|ACD47568.1| cystathionine gamma-synthase/cystathionine beta-lyase [Helicobacter
pylori Shi470]
Length = 380
Score = 621 bits (1604), Expect = e-176, Method: Composition-based stats.
Identities = 133/405 (32%), Positives = 204/405 (50%), Gaps = 27/405 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R+ T +++ G D + +V P+Y ++T++ + Y+YSRSGNPTR L+ I
Sbjct: 2 RMQTKLIHGGISEDAATGAVSVPIYQTSTYRQGAIGRH-KGYEYSRSGNPTRFALEELIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SG+ + + LL D+ ++ GDD+YGGT RL N +
Sbjct: 61 DLEGGVK--GFAFASGLAGIHAVFS---LLQSGDH----VLLGDDVYGGTFRLFNKVLVK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +DTSD + K + K + LE+P+NPL K+ D+ + K
Sbjct: 112 NGLSCTIIDTSDLSQIKKAIKPNTK--ALYLETPSNPLLKITDLVQCASVAKD--HGLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + NPL L G D+V S TKYL GH D++ G++ + +A ++ F N+
Sbjct: 168 IVDNTFATPYCQNPLLL--GADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G L P DSWLL RG+KTLG+R+ Q+NA+ +A +LE K K + GL
Sbjct: 226 IGGVLGPQDSWLLQRGIKTLGLRMEAHQKNALCVAEFLEKH--------PKVEKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P+ +L K G +LSF + + V S L ++ + S G V SL+ +P
Sbjct: 278 SAHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVES--LKLFILGESLGGVESLVGVPAL 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
M+HA I R+ + LVRL GIE+ DL +DL A
Sbjct: 336 MTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG 380
>ref|ZP_01053161.1| Cystathionine gamma-synthase [Tenacibaculum sp. MED152]
gb|EAQ42589.1| Cystathionine gamma-synthase [Polaribacter dokdonensis MED152]
Length = 382
Score = 621 bits (1604), Expect = e-176, Method: Composition-based stats.
Identities = 134/403 (33%), Positives = 205/403 (50%), Gaps = 23/403 (5%)
Query: 5 RLDTVVVNTGSQNDQHSASV-PPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T ++ G +++ + SV PPV+L++TF E + Y Y+R NPTR+ L+
Sbjct: 2 KFNTKTIHGGQMHEETTGSVMPPVFLTSTFAQSSPGEH-KGYAYARGTNPTRTALEASFA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L + A +SGM A+D +LR LL D IIAGDDLYGGT R+ Q+
Sbjct: 61 ALENGT--HAFAFASGMAAIDAVLR---LLKPGDE----IIAGDDLYGGTYRMFTQLFQK 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+VD + E + K + +E+PTNPL K+ DI I VK + + V
Sbjct: 112 YGLEFTYVDMNSIENVTYAITANTK--LIWIETPTNPLMKIADIEEISTKVKDENSEILV 169
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT + PL L G D+V SATKYL GH DL+ G ++ ++A +++F+ +
Sbjct: 170 AVDNTFATPYLQKPLDL--GADIVMHSATKYLGGHSDLVMGALMVNNEKLAKEIHFIQFA 227
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA PMDS+L +RG+KTL VR+ + N + +A +L+ K K + GL
Sbjct: 228 AGAIAGPMDSFLALRGVKTLHVRMQRHCENGLKVAKFLDAHS--------KVGKVYYPGL 279
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++ + + K N G ++SF+ + ++ + S G V SL++ P
Sbjct: 280 ETHESYAIAKKQMNDFGGMVSFKLKDESQKATFAFLESTKLFTLAESLGGVESLVNHPVT 339
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
MSH SI + R + + L+RL GIE+I DL DL A+
Sbjct: 340 MSHGSIPEKERLKIGITDSLIRLSVGIEDIDDLLNDLEQALNA 382
>ref|YP_002774266.1| cystathionine gamma-lyase [Brevibacillus brevis NBRC 100599]
dbj|BAH45762.1| cystathionine gamma-lyase [Brevibacillus brevis NBRC 100599]
Length = 377
Score = 621 bits (1603), Expect = e-176, Method: Composition-based stats.
Identities = 142/401 (35%), Positives = 221/401 (55%), Gaps = 27/401 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
R+ T +++ G D H+ +V P+Y +T+K + + ++YSR+GNPTR L+ I
Sbjct: 2 RIKTRLIHGGIDGDPHTGAVSVPIYQVSTYKQEAIGVH-KGFEYSRTGNPTRHALETYIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
++ A SGM AL IL + N D+ ++ GDD+YGGT R++ +
Sbjct: 61 EIEG--GARGFAFGSGMAALSTILS---MFNKGDH----LVVGDDVYGGTYRVVTRVFSR 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ +VDTSD + + K +++E+PTNPL KV DI + K + +
Sbjct: 112 MGLEATYVDTSDLAAVEAAIRPETK--AIIMETPTNPLLKVSDISALAGIAK--AKGVLL 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VVDNT M+ NPL L G D+V+ SATKYL GH D++ G++++K ++ L+FV N+
Sbjct: 168 VVDNTFMTPYWQNPLDL--GADIVFHSATKYLGGHSDVVAGLVVAKDAQVGEDLHFVQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
G L P DSWLL+RG+KTLG+R+ + + NA LA WL + + GL
Sbjct: 226 IGGVLGPQDSWLLLRGMKTLGIRMEEHEHNARTLAKWLSERSD--------IKRVIYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+ +L + G G ++SF+ GS E + ++ K+ + + S G V SL+S+P +
Sbjct: 278 SSHSGHELIQKQARGFGGMISFDVGSAERADEVL--AKVKYYTLAESLGAVESLISVPAR 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+HASI E R E + LVR+ GIE++ DL +DL A+
Sbjct: 336 MTHASIPAERRAELGITDGLVRISVGIEDVQDLIEDLDQAL 376
>ref|ZP_03949411.1| cystathionine gamma-synthase/cystathionine beta-lyase [Enterococcus
faecalis TX0104]
gb|EEI11151.1| cystathionine gamma-synthase/cystathionine beta-lyase [Enterococcus
faecalis TX0104]
Length = 394
Score = 621 bits (1602), Expect = e-176, Method: Composition-based stats.
Identities = 133/406 (32%), Positives = 203/406 (50%), Gaps = 27/406 (6%)
Query: 2 PIKRLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQH 60
+ +T +++ G D + +V P+Y ++TF+ + + + Y+YSRSGNPTR L+
Sbjct: 15 TFMKFNTKLIHGGISKDTTTGAVSVPIYQTSTFEQNGVGQ-PKEYEYSRSGNPTRHALET 73
Query: 61 QIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFF 120
I +L + A SSG+ + I+ + D+ I+ GDD+YGG+ RLL+
Sbjct: 74 LIAELEG--GSHGFAFSSGLAGIHAIIS---MFGPEDH----ILLGDDVYGGSFRLLDKV 124
Query: 121 KQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPD 180
+ V+ SD + Q K + LE+P+NPL K+ DI + K
Sbjct: 125 FVANGLSYTIVNASDLATIEAAIQPNTK--ALFLETPSNPLLKITDIEAAAKLAK--KHQ 180
Query: 181 TTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFV 240
+VDNT + PL L G D+V S TKYL GH D++ G++++ PE A K+ F+
Sbjct: 181 LLTIVDNTFATPYFQRPLAL--GADIVVHSGTKYLGGHSDVVSGLVVTNHPESAEKIAFL 238
Query: 241 INSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRF 300
N+ GA L P DSWL+ R LKTLGVR+ +NA +A +LE +
Sbjct: 239 QNAIGAVLGPHDSWLVQRSLKTLGVRMAAHAQNAQKIAEFLEAH--------PAVATVYY 290
Query: 301 VGLRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSM 360
GL S+P ++ + +G ++SFE E V + L I+ + S G V SL+ +
Sbjct: 291 PGLASHPGHEIAQKQMSGFSGMISFELAKDEQVVPFVET--LEIFTLAESLGGVESLIEV 348
Query: 361 PCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
P M+HASI E R+ + L+RL GIE DL DL +
Sbjct: 349 PAIMTHASIPKENREAVGIKDGLIRLSVGIEADEDLLADLEKGLQA 394
>ref|YP_001381008.1| Cystathionine gamma-lyase [Anaeromyxobacter sp. Fw109-5]
gb|ABS28024.1| Cystathionine gamma-lyase [Anaeromyxobacter sp. Fw109-5]
Length = 388
Score = 621 bits (1602), Expect = e-176, Method: Composition-based stats.
Identities = 130/412 (31%), Positives = 206/412 (50%), Gaps = 30/412 (7%)
Query: 1 MPIKR--LDTVVVNTGSQNDQHSAS-VPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSV 57
M ++ +T+ ++ G D + + + PVYL++T+ + + Y+YSR+ NPTR
Sbjct: 1 MDDRKLSFETLAIHAGQSPDPTTGAIMTPVYLTSTYVQESPGVH-KGYEYSRTQNPTRHA 59
Query: 58 LQHQIGKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLL 117
LQ + L + LA +SG+ A D IL LL D+ ++ DD+YGGT R+
Sbjct: 60 LQDCLAALEGA--RHGLAFASGLAATDAILH---LLQAGDH----VVVSDDVYGGTFRIF 110
Query: 118 NFFKQQSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCI 177
+ ++ +VD SD + + V +ESPTNP+ K+VD+ + +
Sbjct: 111 DKVYRRHGLEFAYVDMSDARNVERALTP--RTRLVWIESPTNPMLKLVDLAAVAAIAR-- 166
Query: 178 SPDTTVVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKL 237
VVDNT + PL G DVV S TKYLNGH D++GG + + E+ +L
Sbjct: 167 GHGARTVVDNTFATPYFQRPLA--HGIDVVAHSTTKYLNGHSDVIGGAVATSDAELFERL 224
Query: 238 YFVINSTGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATK 297
F+ N+ G SP+DS+L++RGLKTL VR+ + NA+ +A +LE + +
Sbjct: 225 AFLQNAVGGVPSPLDSFLVLRGLKTLHVRMDRHAENALAIARFLERH--------PQVER 276
Query: 298 TRFVGLRSNPDFKLHKSFNNGPGAVLSFET-GSFEHSKRLVSSKKLSIWAVTVSFGCVNS 356
+ GL S+P L + G G +L+F G ++ + + + I+A S G V S
Sbjct: 277 VTYPGLASHPQHDLARRQMTGFGGMLTFVVRGGLAAARAFLENVR--IFACAESLGGVES 334
Query: 357 LLSMPCKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVDAD 408
L+ P M+HAS+ E R++ + +R+ GIE DL DL A
Sbjct: 335 LIEHPAIMTHASVPKETREQLGIADGFIRVSAGIERADDLLADLERGFAAAK 386
>ref|ZP_01909681.1| Cystathionine gamma-synthase [Plesiocystis pacifica SIR-1]
gb|EDM77347.1| Cystathionine gamma-synthase [Plesiocystis pacifica SIR-1]
Length = 391
Score = 621 bits (1602), Expect = e-176, Method: Composition-based stats.
Identities = 128/405 (31%), Positives = 216/405 (53%), Gaps = 28/405 (6%)
Query: 4 KRLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQI 62
+R++T+ ++ G + + + +V P++ ++T+ E ++YSR+ NPTR L+ +
Sbjct: 12 QRIETLAIHGGQEAEPITGAVMQPIFQTSTYVQRSPGEH-TGFEYSRTQNPTRFALERAM 70
Query: 63 GKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQ 122
L + LA +SG A +++ LL+ D+ +IAGDD+YGGT RL + +
Sbjct: 71 AALEGGT--HGLAFASGCAATTTVIQ---LLDAGDH----VIAGDDIYGGTFRLFDKVMR 121
Query: 123 QSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTT 182
+ VD D + F+ F++ K+ V LE+PTNP+ K+ DI I + C
Sbjct: 122 RRGQRFTFVDPRDLDAFEAAFEARTKM--VWLETPTNPMLKLGDIEAIAKM--CRQRGVL 177
Query: 183 VVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
+VVDNT M+ + PL L G D+V S TKY GH D++GG ++ ++ ++ ++L+F+ N
Sbjct: 178 LVVDNTFMTPVFQRPLDL--GADLVVHSTTKYCGGHSDVVGGAVVMRSAKLHAELHFLQN 235
Query: 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVG 302
S GA P D +L +RGLKTL +R+ + NA +A +LE K + + G
Sbjct: 236 SCGAVPGPQDCYLTLRGLKTLALRMERHASNAQRVAEYLEGHA--------KVERVIYPG 287
Query: 303 LRSNPDFKLHKSFNNGPGAVLSFETG-SFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMP 361
L S P +L K +G G ++SF + ++R + + + ++ + S G V SL+ P
Sbjct: 288 LESFPQHELAKRQMSGFGGMVSFYVDSDLDGARRFLEAVR--VFTLAESLGGVESLIEHP 345
Query: 362 CKMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HAS+ R + + +R+ GIE+I DL DL A+
Sbjct: 346 ALMTHASVPKANRDKLGIADGFIRVSVGIEHIDDLIADLERALAA 390
>ref|NP_834078.1| cystathionine beta-lyase [Bacillus cereus ATCC 14579]
ref|ZP_02525947.1| cystathionine beta-lyase [Bacillus cereus AH1134]
gb|AAP11279.1| Cystathionine beta-lyase [Bacillus cereus ATCC 14579]
Length = 377
Score = 621 bits (1602), Expect = e-176, Method: Composition-based stats.
Identities = 139/399 (34%), Positives = 221/399 (55%), Gaps = 27/399 (6%)
Query: 8 TVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLY 66
T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I L
Sbjct: 5 TKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIAVLE 63
Query: 67 RVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHA 126
A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 64 N--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNRFGI 114
Query: 127 VSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVD 186
VDT++ E+ + + K + +E+PTNPL K+ DI +I K D ++D
Sbjct: 115 EHTFVDTTNLEEVEEAIRPNTK--AIYVETPTNPLLKITDIKKISTLAK--EKDLLTIID 170
Query: 187 NTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGA 246
NT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NSTG
Sbjct: 171 NTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNSTGG 228
Query: 247 GLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSN 306
L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL S+
Sbjct: 229 ILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGLESH 280
Query: 307 PDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSH 366
+ +L NG GA++SF+ S E +++ KL + + S G V SL+S+P +M+H
Sbjct: 281 QNHELATEQANGFGAIISFDVDSEETLNKVLE--KLQYFTLAESLGAVESLISIPSQMTH 338
Query: 367 ASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
ASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 339 ASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>ref|ZP_01890642.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[unidentified eubacterium SCB49]
gb|EDM44391.1| Cys/Met metabolism PLP-dependent enzyme superfamily protein
[unidentified eubacterium SCB49]
Length = 380
Score = 621 bits (1602), Expect = e-176, Method: Composition-based stats.
Identities = 122/402 (30%), Positives = 210/402 (52%), Gaps = 26/402 (6%)
Query: 5 RLDTVVVNTGS-QNDQ-HSASVPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQI 62
+ +T ++ G D +++ +PP+Y +TT+ + ++YSRSGNPTR+ L++ +
Sbjct: 2 KFNTKTIHGGQKDIDPAYNSVMPPIYQTTTYAQSTPGGH-KGFEYSRSGNPTRAALENSL 60
Query: 63 GKLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQ 122
+ + LA SG+ A+D +++ LL D +I+ +DLYGG+ RL +
Sbjct: 61 AAIEN--GKFGLAFGSGLAAIDAVIK---LLKPGDE----VISTNDLYGGSYRLFTKIFE 111
Query: 123 QSHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTT 182
+ ++ + K + +E+PTNP+ ++DI K +
Sbjct: 112 GLGIKFHFIGMNNANNIENYINKNTK--LIWVETPTNPMINIIDIKTCAFISK--KHNLL 167
Query: 183 VVVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVIN 242
+ VDNT + NPL G D+V SATKYL GH D++ G +I K +A KLYF+ N
Sbjct: 168 LAVDNTFATPYLQNPLD--HGADIVMHSATKYLGGHSDVVMGALIVKDDALAKKLYFIQN 225
Query: 243 STGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVG 302
++GA P D++L++RG+KTL +R+ + N +AH+L+N+ K + G
Sbjct: 226 ASGAICGPQDAFLVLRGIKTLHLRMQRHCENGKAVAHYLQNN--------PKIENVYWPG 277
Query: 303 LRSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPC 362
++P+ ++ K + G ++SF T +++ + + L ++ + S G V SL P
Sbjct: 278 FENHPNHEIAKEQMSDYGGMVSFTTIGNNYNEAIKIVENLKVFTLAESLGGVESLAGHPA 337
Query: 363 KMSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
M+HASI E R++ + L+RL GIE+I DL +DL A+
Sbjct: 338 SMTHASIPKEEREKTGVVDSLIRLSVGIEDIEDLIEDLEQAI 379
>ref|ZP_02254620.1| cystathionine beta-lyase [Bacillus cereus AH187]
ref|ZP_02596382.1| cystathionine beta-lyase [Bacillus cereus H3081.97]
Length = 377
Score = 620 bits (1601), Expect = e-176, Method: Composition-based stats.
Identities = 138/399 (34%), Positives = 221/399 (55%), Gaps = 27/399 (6%)
Query: 8 TVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIGKLY 66
T +++ + + SV P+Y ++T+K + + Q Y+YSR+GNPTR+ L+ I L
Sbjct: 5 TKLIHGIRIGEPSTGSVNVPIYQTSTYKQEAVGKH-QGYEYSRTGNPTRAALEEMIAVLE 63
Query: 67 RVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQSHA 126
A SGM A+ + +L + D+ +I DD+YGGT R++ +
Sbjct: 64 N--GHAGFAFGSGMAAITATI---MLFSKGDH----VILTDDVYGGTYRVITKVLNRFGI 114
Query: 127 VSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTVVVD 186
VDT++ E+ + + K + +E+PTNPL K+ DI +I K D ++D
Sbjct: 115 EHTFVDTTNLEEVEEAIRPNTK--AIYVETPTNPLLKITDIKKISTLAK--EKDLLTIID 170
Query: 187 NTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINSTGA 246
NT M+ +P+ L G D+V SATKYL GH D++ G+++ +P++A L+FV NSTG
Sbjct: 171 NTFMTPYWQSPISL--GADIVLHSATKYLGGHSDVVAGLVVVNSPQLAEDLHFVQNSTGG 228
Query: 247 GLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGLRSN 306
L P DS+LL+RGLKTLG+R+ + + N+ +A +L N K K + GL S+
Sbjct: 229 ILGPQDSFLLLRGLKTLGIRMEEHETNSRAIAEFLNNH--------PKVNKVYYPGLESH 280
Query: 307 PDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCKMSH 366
+ +L NG GA++SF+ S E +++ +L + + S G V SL+S+P +M+H
Sbjct: 281 QNHELATEQANGFGAIISFDVDSEETLNKVLE--RLQYFTLAESLGAVESLISIPSQMTH 338
Query: 367 ASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMV 405
ASI + RKE + L+R+ GIE+ DL +DL A+
Sbjct: 339 ASIPADRRKELGITDTLIRISVGIEDGEDLIEDLAQALA 377
>ref|NP_814082.1| cystathionine gamma-synthase/cystathionine beta-lyase [Enterococcus
faecalis V583]
gb|AAO80153.1| cystathionine beta-lyase [Enterococcus faecalis V583]
Length = 378
Score = 620 bits (1601), Expect = e-176, Method: Composition-based stats.
Identities = 133/403 (33%), Positives = 204/403 (50%), Gaps = 27/403 (6%)
Query: 5 RLDTVVVNTGSQNDQHSASVP-PVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
+ +T +++ G D + +V P+Y ++TF+ + + + Y+YSRSGNPTR L+ I
Sbjct: 2 KFNTKLIHGGISKDTTTGAVSVPIYQTSTFEQNGVGQ-PKEYEYSRSGNPTRHALETLIA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
+L + A SSG+ + I+ + D+ I+ GDD+YGG+ RLL+
Sbjct: 61 ELEG--GSHGFAFSSGLAGIHAIIS---MFGPEDH----ILLGDDVYGGSFRLLDKVFVA 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
+ V+ SD + Q K + LE+P+NPL K+ DI + K
Sbjct: 112 NGLSYTIVNASDLSTIEAAIQPNTK--ALFLETPSNPLLKITDIEAAAKLAK--KHQLLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
+VDNT + PL L G D+V S TKYL GH D++ G++++ PE A K+ F+ N+
Sbjct: 168 IVDNTFATPYFQRPLAL--GADIVVHSGTKYLGGHSDVVSGLVVTNHPESAEKIAFLQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
GA L P DSWL+ R LKTLGVR+ +NA +A +LE + GL
Sbjct: 226 IGAVLGPHDSWLVQRSLKTLGVRMAAHAQNAQKIAEFLEAH--------PAVATVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
S+P ++ + +G ++SFE E V + L I+ + S G V SL+ +P
Sbjct: 278 ASHPGHEIAQKQMSGFSGMISFELAKDEQVVPFVEA--LEIFTLAESLGGVESLIEVPAI 335
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAMVD 406
M+HASI E R+ + L+RL GIE + DL DL +
Sbjct: 336 MTHASIPKENREAVGIKDGLIRLSVGIEAVEDLLADLEKGLQA 378
>ref|ZP_03899337.1| cystathionine gamma-lyase [Dyadobacter fermentans DSM 18053]
gb|EEJ30761.1| cystathionine gamma-lyase [Dyadobacter fermentans DSM 18053]
Length = 381
Score = 620 bits (1601), Expect = e-176, Method: Composition-based stats.
Identities = 131/401 (32%), Positives = 203/401 (50%), Gaps = 25/401 (6%)
Query: 5 RLDTVVVNTGSQNDQHSAS-VPPVYLSTTFKVDLNNEDAQNYDYSRSGNPTRSVLQHQIG 63
T ++ G + D + + + P+Y ++T+ + + + Y+Y RS NPTR+ LQ +
Sbjct: 2 NFATKAIHAGVEPDPATGAIMTPIYQTSTYVQESPGKH-KGYEYGRSSNPTRTALQTALA 60
Query: 64 KLYRVPQENVLAVSSGMTALDVILRGLVLLNGTDNHTPTIIAGDDLYGGTQRLLNFFKQQ 123
L ++ L +SG+ A D +L+ L D IIA D+YGGT RL+ +
Sbjct: 61 ALEN--GKHGLCYASGLAATDAVLK---LFRPGDE----IIAPSDIYGGTYRLMKRIFEP 111
Query: 124 SHAVSVHVDTSDFEKFKTVFQSLDKVDCVLLESPTNPLCKVVDIPRILRFVKCISPDTTV 183
V +D + + + K V LE+PTNPL K++DI ++ R K +
Sbjct: 112 LGLVFRFIDLEEVPAIAQLISA--KTRMVWLETPTNPLLKIIDIEQVTRICK--ERNVLT 167
Query: 184 VVDNTMMSGLNCNPLQLNPGCDVVYESATKYLNGHHDLMGGVIISKTPEIASKLYFVINS 243
VDNT S NPL L G D+V S TKYL GH D + G +++ E+A++L F+ N+
Sbjct: 168 CVDNTFASPYLQNPLDL--GADMVMHSVTKYLGGHSDTVMGALVTSNDELAAQLKFIQNA 225
Query: 244 TGAGLSPMDSWLLVRGLKTLGVRLYQQQRNAMILAHWLENSCGFKPTRTNKATKTRFVGL 303
+GA P D +L++RGLKTL +R+ + NA +A WL K K + GL
Sbjct: 226 SGAVPGPQDCFLVLRGLKTLHIRMQRHCENAAQVAVWLSAH--------PKVGKVYYPGL 277
Query: 304 RSNPDFKLHKSFNNGPGAVLSFETGSFEHSKRLVSSKKLSIWAVTVSFGCVNSLLSMPCK 363
++P +L G G V+SFE + + + + L I+A+ S G V SL + P
Sbjct: 278 PAHPGHELAARQMRGFGGVVSFELKDDSYQTAVRTMENLQIFALGESLGGVESLCTHPAS 337
Query: 364 MSHASIDPELRKERDFPEDLVRLCCGIENIVDLKKDLLAAM 404
MSH + E R + + L+RL GIE++ DL DL A+
Sbjct: 338 MSHGGMPREERLKIGLKDTLIRLSVGIEDVEDLIADLDQAI 378
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.314 0.188 0.655
Lambda K H
0.267 0.0576 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,604,944,865
Number of Sequences: 6899187
Number of extensions: 635808014
Number of successful extensions: 1314092
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 8840
Number of HSP's successfully gapped in prelim test: 4353
Number of HSP's that attempted gapping in prelim test: 1236959
Number of HSP's gapped (non-prelim): 16775
length of query: 465
length of database: 2,350,152,223
effective HSP length: 138
effective length of query: 327
effective length of database: 1,398,064,417
effective search space: 457167064359
effective search space used: 457167064359
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 82 (35.7 bits)