BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= YIR034C__[Saccharomyces_cerevisiae]
(373 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
pdb|2QRJ|A Chain A, Crystal Structure Of Sulfate-Bound Sacc... 761 0.0
ref|NP_012300.1| Saccharopine dehydrogenase (NAD+, L-lysine... 759 0.0
emb|CAA54551.1| saccharopine dehydrogenase (NAD+, L-lysine ... 758 0.0
pdb|2Q99|A Chain A, Crystal Structure Of Saccharopine Dehyd... 751 0.0
ref|XP_446267.1| unnamed protein product [Candida glabrata]... 627 e-178
ref|XP_454310.1| unnamed protein product [Kluyveromyces lac... 599 e-169
ref|XP_001643683.1| hypothetical protein Kpol_1057p13 [Vand... 594 e-168
ref|XP_001387327.1| Saccharopine dehydrogenase [NAD+, L-lys... 567 e-160
ref|XP_001523078.1| saccharopine dehydrogenase [Lodderomyce... 567 e-160
ref|XP_457987.1| hypothetical protein DEHA0C07832g [Debaryo... 565 e-159
ref|NP_983569.1| ACR167Cp [Ashbya gossypii ATCC 10895] >gi|... 548 e-154
sp|P43065|LYS1_CANAL Saccharopine dehydrogenase [NAD+, L-ly... 546 e-153
ref|XP_001482345.1| hypothetical protein PGUG_05365 [Pichia... 533 e-149
ref|XP_500931.1| YlLYS5 [Yarrowia lipolytica] >gi|729965|sp... 498 e-139
ref|XP_964977.1| saccharopine dehydrogenase [Neurospora cra... 426 e-117
ref|NP_592972.1| saccharopine dehydrogenase [NAD+, L-lysine... 424 e-117
ref|XP_001908761.1| unnamed protein product [Podospora anse... 420 e-115
ref|XP_001593244.1| saccharopine dehydrogenase [Sclerotinia... 419 e-115
gb|EDU47954.1| saccharopine dehydrogenase [Pyrenophora trit... 417 e-115
ref|XP_001559795.1| saccharopine dehydrogenase [Botryotinia... 416 e-114
ref|XP_711455.1| saccharopine dehydrogenase [Candida albica... 415 e-114
ref|XP_001213891.1| hypothetical protein ATEG_04713 [Asperg... 413 e-113
ref|XP_754450.1| saccharopine dehydrogenase Lys1 [Aspergill... 412 e-113
ref|XP_001263295.1| saccharopine dehydrogenase Lys1, putati... 412 e-113
ref|XP_001803532.1| hypothetical protein SNOG_13323 [Phaeos... 412 e-113
ref|XP_001399884.1| hypothetical protein An02g07500 [Asperg... 409 e-112
ref|XP_001271170.1| saccharopine dehydrogenase Lys1, putati... 409 e-112
ref|XP_363433.1| hypothetical protein MGG_01359 [Magnaporth... 407 e-112
ref|XP_660477.1| hypothetical protein AN2873.2 [Aspergillus... 406 e-111
ref|XP_001246345.1| hypothetical protein CIMG_00116 [Coccid... 405 e-111
sp|Q870G1|LYS1_EMENI Saccharopine dehydrogenase [NAD+, L-ly... 404 e-111
ref|XP_001220083.1| hypothetical protein CHGG_00862 [Chaeto... 400 e-110
ref|XP_001819876.1| hypothetical protein [Aspergillus oryza... 398 e-109
gb|EEH34800.1| saccharopine dehydrogenase [Paracoccidioides... 385 e-105
ref|XP_001828899.1| hypothetical protein CC1G_03693 [Coprin... 366 1e-99
ref|XP_570078.1| saccharopine dehydrogenase (NAD+, L-lysine... 361 4e-98
ref|XP_001544099.1| saccharopine dehydrogenase [Ajellomyces... 358 3e-97
ref|XP_001745712.1| predicted protein [Monosiga brevicollis... 354 7e-96
emb|CAX65448.1| putative saccharopine dehydrogenase (NAD+,L... 353 1e-95
ref|XP_001873276.1| predicted protein [Laccaria bicolor S23... 351 6e-95
gb|EEH50065.1| saccharopine dehydrogenase [Paracoccidioides... 343 1e-92
ref|XP_391101.1| hypothetical protein FG10925.1 [Gibberella... 342 2e-92
ref|XP_760415.1| hypothetical protein UM04268.1 [Ustilago m... 337 1e-90
ref|XP_001732779.1| hypothetical protein MGL_0554 [Malassez... 306 2e-81
ref|XP_001634023.1| predicted protein [Nematostella vectens... 291 4e-77
ref|YP_612102.1| alanine dehydrogenase/PNT-like [Silicibact... 273 2e-71
ref|ZP_01901689.1| saccharopine dehydrogenase, putative [Ro... 273 2e-71
ref|YP_132774.1| hypothetical saccharopine dehydrogenase [P... 272 3e-71
ref|ZP_01219314.1| hypothetical saccharopine dehydrogenase ... 271 6e-71
ref|ZP_00630414.1| Alanine dehydrogenase/PNT, C-terminal:Al... 270 2e-70
ref|ZP_01057918.1| saccharopine dehydrogenase, putative [Ro... 267 1e-69
ref|ZP_00948710.1| saccharopine dehydrogenase (NAD+, L-lysi... 267 1e-69
ref|ZP_00954164.1| saccharopine dehydrogenase (NAD+, L-lysi... 265 4e-69
ref|YP_001044623.1| alanine dehydrogenase/PNT domain protei... 265 6e-69
ref|ZP_01446787.1| saccharopine dehydrogenase (NAD+, L-lysi... 264 8e-69
ref|ZP_01034544.1| saccharopine dehydrogenase, putative [Ro... 264 9e-69
ref|YP_354173.1| saccharopine dehydrogenase (NAD+, L-lysine... 264 1e-68
ref|ZP_01002428.1| saccharopine dehydrogenase (NAD+, L-lysi... 261 5e-68
ref|ZP_01881158.1| saccharopine dehydrogenase, putative [Ro... 258 4e-67
ref|ZP_02143453.1| saccharopine dehydrogenase, putative [Ro... 258 4e-67
ref|ZP_02152850.1| saccharopine dehydrogenase, putative [Oc... 258 5e-67
ref|YP_001169133.1| Saccharopine dehydrogenase (NAD(+), L-l... 258 6e-67
ref|ZP_01154744.1| saccharopine dehydrogenase (NAD+, L-lysi... 256 2e-66
ref|YP_168503.1| saccharopine dehydrogenase, putative [Sili... 256 3e-66
ref|ZP_01753990.1| saccharopine dehydrogenase, putative [Ro... 253 1e-65
ref|YP_681080.1| saccharopine dehydrogenase, putative [Rose... 253 2e-65
ref|ZP_01751929.1| saccharopine dehydrogenase, putative [Ro... 253 2e-65
ref|ZP_00959701.1| saccharopine dehydrogenase, putative [Ro... 251 5e-65
ref|YP_511957.1| Saccharopine dehydrogenase (NAD+, L-lysine... 250 1e-64
ref|ZP_02150991.1| saccharopine dehydrogenase, putative [Ph... 248 5e-64
ref|ZP_02146801.1| saccharopine dehydrogenase, putative [Ph... 246 2e-63
ref|ZP_01746654.1| saccharopine dehydrogenase, putative [Sa... 244 8e-63
ref|ZP_01442866.1| saccharopine dehydrogenase, putative [Ro... 243 2e-62
ref|ZP_01740684.1| saccharopine dehydrogenase, putative [Rh... 240 2e-61
ref|NP_822964.1| saccharopine dehydrogenase [Streptomyces a... 221 9e-56
ref|YP_001535948.1| alanine dehydrogenase/PNT domain protei... 212 5e-53
ref|ZP_01121461.1| hypothetical saccharopine dehydrogenase ... 94 1e-17
ref|XP_001842086.1| alpha-aminoadipic semialdehyde synthase... 90 2e-16
ref|ZP_01728427.1| hypothetical protein CY0110_25071 [Cyano... 90 3e-16
ref|ZP_00533414.1| Alanine dehydrogenase/PNT, C-terminal:Al... 89 4e-16
ref|XP_001744925.1| predicted protein [Monosiga brevicollis... 89 8e-16
ref|XP_001634024.1| predicted protein [Nematostella vectens... 87 3e-15
ref|ZP_01718580.1| putative saccharopine dehydrogenase [Alg... 85 1e-14
ref|XP_797286.2| PREDICTED: similar to saccharopine dehydro... 84 2e-14
ref|XP_684074.2| PREDICTED: similar to lysine ketoglutarate... 83 3e-14
ref|XP_001649464.1| saccharopine dehydrogenase [Aedes aegyp... 82 5e-14
ref|XP_314728.3| AGAP008632-PA [Anopheles gambiae str. PEST... 81 2e-13
ref|XP_971717.1| PREDICTED: similar to CG7144-PA [Tribolium... 80 3e-13
ref|XP_416001.2| PREDICTED: hypothetical protein [Gallus ga... 79 4e-13
ref|NP_001118002.1| lysine ketoglutarate reductase/saccharo... 79 8e-13
emb|CAG01078.1| unnamed protein product [Tetraodon nigrovir... 78 1e-12
ref|XP_624513.2| PREDICTED: similar to CG7144-PA [Apis mell... 77 2e-12
ref|NP_001011437.1| hypothetical protein LOC496923 [Xenopus... 77 2e-12
ref|XP_001607166.1| PREDICTED: similar to ENSANGP0000001314... 77 3e-12
ref|NP_001085980.1| MGC82978 protein [Xenopus laevis] >gi|4... 77 3e-12
ref|YP_001805104.1| unknown [Cyanothece sp. ATCC 51142] >gi... 76 4e-12
ref|XP_638394.1| aminoadipic semialdehyde synthase [Dictyos... 73 3e-11
ref|NP_001103267.1| aminoadipate-semialdehyde synthase [Bos... 73 3e-11
ref|XP_001370253.1| PREDICTED: similar to lysine ketoglutar... 72 6e-11
ref|NP_609150.2| CG7144 CG7144-PA [Drosophila melanogaster]... 72 6e-11
ref|XP_001356475.1| GA20134-PA [Drosophila pseudoobscura] >... 72 7e-11
ref|XP_566629.1| saccharopine dehydrogenase [Cryptococcus n... 72 9e-11
gb|AAR82744.1| SD02276p [Drosophila melanogaster] 72 9e-11
gb|EEJ79866.1| alanine dehydrogenase [Kangiella koreensis D... 71 1e-10
ref|XP_778221.1| hypothetical protein CNBA2210 [Cryptococcu... 71 1e-10
ref|XP_001672092.1| Hypothetical protein CBG13546 [Caenorha... 69 5e-10
ref|ZP_01202579.1| putative dehydrogenase [Flavobacteria ba... 69 6e-10
ref|YP_001295405.1| Putative monofunctional lysine-ketoglut... 69 6e-10
ref|YP_862590.1| lysine 2-oxoglutarate reductase [Gramella ... 69 8e-10
ref|NP_499884.1| R02D3.1 [Caenorhabditis elegans] >gi|27363... 68 1e-09
ref|XP_001502225.1| PREDICTED: similar to lysine ketoglutar... 67 2e-09
ref|XP_539546.2| PREDICTED: similar to aminoadipate-semiald... 66 5e-09
ref|ZP_01687098.1| hypothetical protein M23134_02084 [Micro... 65 1e-08
ref|YP_001197105.1| alanine dehydrogenase/PNT domain protei... 65 1e-08
ref|YP_679948.1| hypothetical protein CHU_3369 [Cytophaga h... 64 2e-08
ref|ZP_02188470.1| hypothetical protein BAL199_04779 [alpha... 64 2e-08
ref|ZP_01119038.1| saccharopine dehydrogenase, putative [Po... 63 3e-08
ref|XP_001145257.1| PREDICTED: aminoadipate-semialdehyde sy... 63 5e-08
emb|CAA07619.2| lysine-ketoglutarate reductase /saccharopin... 62 1e-07
ref|NP_005754.2| aminoadipate-semialdehyde synthase [Homo s... 62 1e-07
ref|ZP_00948992.1| hypothetical saccharopine dehydrogenase ... 61 1e-07
ref|XP_001630319.1| predicted protein [Nematostella vectens... 61 1e-07
ref|NP_001094433.1| aminoadipate-semialdehyde synthase [Rat... 61 2e-07
ref|ZP_01891601.1| hypothetical protein SCB49_01387 [uniden... 60 2e-07
ref|NP_038958.2| aminoadipate-semialdehyde synthase precurs... 60 2e-07
dbj|BAE22882.1| unnamed protein product [Mus musculus] 60 2e-07
emb|CAA12114.1| lysine ketoglutarate reductase/saccharopine... 60 2e-07
ref|ZP_02163121.1| hypothetical protein KAOT1_11306 [Kordia... 60 3e-07
ref|ZP_01734750.1| hypothetical protein FBBAL38_11809 [Flav... 60 4e-07
ref|ZP_02182261.1| hypothetical protein FBALC1_04707 [Flavo... 59 4e-07
ref|ZP_01061856.1| hypothetical saccharopine dehydrogenase ... 59 5e-07
ref|ZP_01253400.1| saccharopine dehydrogenase, putative [Ps... 55 8e-06
ref|XP_001838392.1| hypothetical protein CC1G_12484 [Coprin... 55 1e-05
ref|XP_001021580.1| Alanine dehydrogenase/PNT, N-terminal d... 54 2e-05
ref|ZP_01054061.1| saccharopine dehydrogenase, putative [Te... 52 5e-05
ref|XP_001889650.1| predicted protein [Laccaria bicolor S23... 51 1e-04
ref|ZP_01051455.1| putative saccharopine dehydrogenase [Cel... 51 2e-04
ref|XP_001620022.1| hypothetical protein NEMVEDRAFT_v1g6152... 50 2e-04
gb|AAN14411.1| monofunctional lysine-ketoglutarate reductas... 50 3e-04
gb|AAN14410.1| bifunctional lysine-ketoglutarate reductase/... 50 4e-04
emb|CAO65167.1| unnamed protein product [Vitis vinifera] 50 4e-04
ref|ZP_01264036.1| alanine dehydrogenase [Candidatus Pelagi... 49 6e-04
gb|EAY87774.1| hypothetical protein OsI_009007 [Oryza sativ... 48 0.001
gb|EAZ24849.1| hypothetical protein OsJ_008332 [Oryza sativ... 48 0.001
ref|XP_001777036.1| predicted protein [Physcomitrella paten... 47 0.002
ref|YP_266230.1| alanine dehydrogenase [Candidatus Pelagiba... 47 0.003
gb|AAK18179.1|AF325208_1 nicotinamide nucleotide transhydro... 47 0.003
gb|AAG02246.2| NAD(P)H transhydrogenase [Acetabularia aceta... 47 0.003
ref|NP_001104873.1| lysine-ketoglutarate reductase/saccharo... 47 0.003
ref|XP_001428538.1| hypothetical protein GSPATT00031371001 ... 46 0.004
ref|YP_001528954.1| alanine dehydrogenase [Desulfococcus ol... 46 0.004
ref|YP_001854051.1| alanine dehydrogenase [Kocuria rhizophi... 45 0.011
ref|ZP_02941837.1| alanine dehydrogenase [Cyanothece sp. PC... 44 0.018
ref|NP_567914.1| LKR (SACCHAROPINE DEHYDROGENASE) [Arabidop... 44 0.020
gb|AAB96826.1| lysine-ketoglutarate reductase/saccharopine ... 44 0.020
gb|AAB96825.1| lysine-ketoglutarate reductase/saccharopine ... 44 0.020
sp|Q9SMZ4|AASS_ARATH Alpha-aminoadipic semialdehyde synthas... 44 0.021
gb|AAK97099.1|AF295389_1 monofunctional lysine-ketoglutarat... 44 0.021
gb|AAB53975.1| lysine-ketoglutarate reductase/saccharopine ... 44 0.022
ref|XP_367628.1| conserved hypothetical protein [Magnaporth... 43 0.035
ref|ZP_01719176.1| proton-translocating transhydrogenase, s... 43 0.049
ref|ZP_01233072.1| putative alanine dehydrogenase [Vibrio a... 43 0.049
ref|ZP_01158968.1| putative alanine dehydrogenase [Photobac... 43 0.050
ref|YP_001126767.1| Alanine dehydrogenase [Geobacillus ther... 42 0.058
ref|ZP_03892568.1| NAD(P) transhydrogenase, alpha subunit [... 42 0.059
gb|EDU41373.1| NAD(P) transhydrogenase, mitochondrial precu... 42 0.073
ref|YP_628213.1| alanine dehydrogenase [Helicobacter pylori... 42 0.10
ref|ZP_01520496.1| NAD(P) transhydrogenase, alpha subunit [... 42 0.11
ref|NP_208189.1| alanine dehydrogenase (ald) [Helicobacter ... 41 0.12
ref|YP_001632786.1| NAD(P) transhydrogenase subunit alpha [... 41 0.13
ref|ZP_03900458.1| L-alanine dehydrogenase [Dyadobacter fer... 41 0.13
ref|ZP_02428013.1| hypothetical protein CLORAM_01403 [Clost... 41 0.13
ref|ZP_00738801.1| Alanine dehydrogenase [Bacillus thuringi... 41 0.14
ref|ZP_02178789.1| NAD(P)(+) transhydrogenase (AB-specific)... 41 0.15
ref|YP_461225.1| alanine dehydrogenase [Syntrophus aciditro... 41 0.17
ref|ZP_02330643.1| alanine dehydrogenase [Paenibacillus lar... 41 0.19
ref|YP_075651.1| alanine dehydrogenase [Symbiobacterium the... 41 0.20
ref|YP_747411.1| NAD(P)(+) transhydrogenase (AB-specific) [... 41 0.20
ref|YP_833355.1| alanine dehydrogenase/PNT domain protein [... 40 0.21
ref|ZP_02433787.1| hypothetical protein CLOSCI_04072 [Clost... 40 0.21
ref|ZP_01306334.1| pyridine nucleotide transhydrogenase alp... 40 0.22
ref|YP_645660.1| NAD(P)(+) transhydrogenase (AB-specific) [... 40 0.23
ref|YP_001832691.1| alanine dehydrogenase [Beijerinckia ind... 40 0.24
ref|YP_411850.1| alanine dehydrogenase [Nitrosospira multif... 40 0.26
ref|YP_863990.1| alanine dehydrogenase [Magnetococcus sp. M... 40 0.27
ref|ZP_01666824.1| alanine dehydrogenase [Thermosinus carbo... 40 0.27
ref|YP_001910999.1| alanine dehydrogenase [Helicobacter pyl... 40 0.28
ref|ZP_00952239.1| alanine dehydrogenase [Oceanicaulis alex... 40 0.28
ref|ZP_01996280.1| hypothetical protein DORLON_02287 [Dorea... 40 0.29
ref|ZP_00112172.1| COG0686: Alanine dehydrogenase [Nostoc p... 40 0.29
ref|ZP_03933079.1| L-alanine dehydrogenase [Corynebacterium... 40 0.31
ref|YP_517218.1| hypothetical protein DSY0985 [Desulfitobac... 40 0.33
ref|NP_224146.1| L-ALANINE DEHYDROGENASE [Helicobacter pylo... 40 0.36
gb|EEK02004.1| NAD(P) transhydrogenase, alpha subunit [Tsuk... 40 0.36
ref|YP_579810.1| alanine dehydrogenase/PNT-like [Psychrobac... 40 0.37
ref|YP_001801454.1| alanine dehydrogenase [Cyanothece sp. A... 40 0.37
ref|YP_359521.1| alanine dehydrogenase [Carboxydothermus hy... 40 0.40
emb|CAB88572.2| related to mitochondrial nicotinamide nucle... 39 0.45
ref|ZP_02204914.1| Alanine dehydrogenase [Dehalococcoides s... 39 0.49
ref|YP_474564.1| alanine dehydrogenase [Synechococcus sp. J... 39 0.50
ref|XP_961047.2| NAD(P) transhydrogenase, mitochondrial pre... 39 0.50
ref|YP_001098682.1| NAD(P) transhydrogenase subunit alpha [... 39 0.51
ref|ZP_00513142.1| Alanine dehydrogenase and pyridine nucle... 39 0.52
ref|YP_263850.1| putative pyridine nucleotide transhydrogen... 39 0.56
ref|NP_641270.1| pyridine nucleotide transhydrogenase [Xant... 39 0.56
ref|YP_746463.1| alanine dehydrogenase [Nitrosomonas eutrop... 39 0.57
ref|NP_840933.1| Alanine dehydrogenase and pyridine nucleot... 39 0.57
ref|XP_001266253.1| nicotinamide nucleotide transhydrogenas... 39 0.58
ref|ZP_01164841.1| alanine dehydrogenase [Oceanospirillum s... 39 0.60
ref|YP_001192379.1| alanine dehydrogenase [Flavobacterium j... 39 0.61
ref|ZP_03878002.1| L-alanine dehydrogenase [Haliangium ochr... 39 0.61
ref|NP_840123.1| alanine dehydrogenase [Nitrosomonas europa... 39 0.63
gb|AAQ87237.1| NAD(P) transhydrogenase subunit alpha [Rhizo... 39 0.65
emb|CAF99856.1| unnamed protein product [Tetraodon nigrovir... 39 0.68
ref|YP_662032.1| alanine dehydrogenase [Pseudoalteromonas a... 39 0.73
ref|ZP_01085184.1| putative nicotinamide nucleotide transhy... 39 0.78
ref|YP_374584.1| Alanine dehydrogenase and pyridine nucleot... 39 0.78
ref|YP_320697.1| Alanine dehydrogenase and pyridine nucleot... 39 0.79
ref|YP_001858761.1| NAD(P)(+) transhydrogenase (AB-specific... 39 0.80
ref|YP_148605.1| alanine dehydrogenase [Geobacillus kaustop... 39 0.82
ref|YP_366916.1| NAD(P) transhydrogenase subunit alpha [Bur... 39 0.84
ref|XP_001339438.1| PREDICTED: similar to lysine ketoglutar... 39 0.85
ref|ZP_02975481.1| NAD(P) transhydrogenase, alpha subunit [... 39 0.85
gb|ABF18958.1| lysine ketoglutarate reductase/saccharopine ... 39 0.86
ref|ZP_03864212.1| NAD/NADP transhydrogenase alpha subunit ... 39 0.87
ref|YP_001185975.1| alanine dehydrogenase [Pseudomonas mend... 39 0.88
ref|YP_001453179.1| hypothetical protein CKO_01611 [Citroba... 39 0.95
ref|YP_001369930.1| alanine dehydrogenase/PNT domain protei... 39 0.97
ref|NP_541301.1| NAD(P) TRANSHYDROGENASE SUBUNIT ALPHA [Bru... 38 0.99
ref|NP_700139.1| NAD(P) transhydrogenase, alpha subunit [Br... 38 1.00
ref|YP_223056.1| PntA, NAD(P) transhydrogenase, alpha subun... 38 1.0
ref|YP_001257889.1| NAD(P) transhydrogenase, alpha subunit ... 38 1.0
ref|NP_440110.1| alanine dehydrogenase [Synechocystis sp. P... 38 1.0
ref|ZP_01551565.1| NAD(P)(+) transhydrogenase (AB-specific)... 38 1.1
ref|YP_001301882.1| alanine dehydrogenase [Parabacteroides ... 38 1.1
ref|ZP_02847975.1| alanine dehydrogenase [Paenibacillus sp.... 38 1.1
ref|YP_911378.1| alanine dehydrogenase [Chlorobium phaeobac... 38 1.1
ref|ZP_03815724.1| NAD/NADP transhydrogenase alpha subunit ... 38 1.1
ref|YP_174267.1| stage V sporulation protein N, alanine deh... 38 1.1
ref|ZP_02649469.1| NAD(P) transhydrogenase subunit alpha [S... 38 1.1
ref|YP_001588062.1| hypothetical protein SPAB_01836 [Salmon... 38 1.1
ref|YP_150631.1| NAD(P) transhydrogenase subunit alpha [Sal... 38 1.2
ref|ZP_02697036.1| NAD(P) transhydrogenase subunit alpha [S... 38 1.2
ref|ZP_02135807.1| NAD(P) transhydrogenase subunit alpha [V... 38 1.2
ref|YP_001352066.1| NAD(P) transhydrogenase subunit alpha [... 38 1.2
ref|YP_001529018.1| alanine dehydrogenase [Desulfococcus ol... 38 1.3
ref|YP_206544.1| pyridine nucleotide transhydrogenase, alph... 38 1.3
ref|YP_314402.1| alanine dehydrogenase [Thiobacillus denitr... 38 1.3
ref|YP_001570537.1| hypothetical protein SARI_01499 [Salmon... 38 1.4
dbj|BAA77513.1| alanine dehydrogenase [Enterobacter aerogenes] 38 1.4
gb|EDM15159.1| aminoadipate-semialdehyde synthase (predicte... 38 1.5
ref|ZP_01628294.1| alanine dehydrogenase [Nodularia spumige... 38 1.5
ref|YP_063028.1| NADP-transhydrogenase [Leifsonia xyli subs... 38 1.5
ref|ZP_01864234.1| alanine dehydrogenase/PNT-like protein [... 38 1.6
ref|YP_923679.1| alanine dehydrogenase [Nocardioides sp. JS... 38 1.6
gb|EEH46870.1| NAD(P) transhydrogenase [Paracoccidioides br... 37 1.7
ref|YP_001327051.1| alanine dehydrogenase [Sinorhizobium me... 37 1.7
gb|EDP51129.1| nicotinamide nucleotide transhydrogenase, pu... 37 1.7
ref|ZP_01113609.1| NAD(P) transhydrogenase subunit alpha [R... 37 1.7
ref|ZP_01891777.1| putative alanine dehydrogenase [unidenti... 37 1.8
ref|XP_001538507.1| NAD(P) transhydrogenase, mitochondrial ... 37 1.8
ref|XP_748064.2| nicotinamide nucleotide transhydrogenase [... 37 1.8
ref|ZP_02564585.1| NAD(P) transhydrogenase subunit alpha [S... 37 1.8
ref|ZP_01224625.1| Alanine dehydrogenase [marine gamma prot... 37 1.8
ref|YP_411846.1| NAD(P)(+) transhydrogenase (AB-specific) [... 37 1.9
ref|XP_001456499.1| hypothetical protein GSPATT00022271001 ... 37 1.9
ref|YP_001917832.1| L-alanine dehydrogenase [Natranaerobius... 37 1.9
ref|XP_001549171.1| conserved hypothetical protein [Botryot... 37 2.0
ref|ZP_02844369.1| NAD(P) transhydrogenase, alpha subunit [... 37 2.1
ref|YP_434236.1| NAD(P) transhydrogenase subunit alpha [Hah... 37 2.1
ref|YP_001720683.1| NAD(P) transhydrogenase, alpha subunit ... 37 2.1
ref|YP_001400805.1| NAD(P) transhydrogenase, alpha subunit ... 37 2.2
ref|YP_070740.1| NAD(P) transhydrogenase subunit alpha [Yer... 37 2.2
ref|NP_405840.1| NAD(P) transhydrogenase subunit alpha [Yer... 37 2.2
ref|YP_001894339.1| NAD(P)(+) transhydrogenase (AB-specific... 37 2.2
ref|YP_001872721.1| NAD(P) transhydrogenase, alpha subunit ... 37 2.2
ref|XP_970382.1| PREDICTED: similar to nicotinamide nucleot... 37 2.2
ref|YP_416780.1| alanine dehydrogenase [Staphylococcus aure... 37 2.4
ref|YP_277175.1| NAD(P) transhydrogenase, subunit alpha par... 37 2.4
ref|YP_202272.1| pyridine nucleotide transhydrogenase [Xant... 37 2.4
ref|NP_621858.1| Alanine dehydrogenase [Thermoanaerobacter ... 37 2.4
pdb|1PJB|A Chain A, L-Alanine Dehydrogenase >gi|5542489|pdb... 37 2.5
ref|YP_002835579.1| Alanine dehydrogenase [Corynebacterium ... 37 2.5
ref|YP_001929236.1| putative NADPH-NAD transhydrogenase [Po... 37 2.5
ref|YP_001681700.1| alanine dehydrogenase [Caulobacter sp. ... 37 2.5
ref|ZP_01644889.1| alanine dehydrogenase/PNT-like [Stenotro... 37 2.6
ref|XP_001400109.1| hypothetical protein An02g09810 [Asperg... 37 2.6
ref|ZP_01914964.1| NAD/NADP transhydrogenase, NAD(H)-bindin... 37 2.6
ref|XP_001025021.1| hypothetical protein TTHERM_00467250 [T... 37 2.6
ref|XP_001276253.1| nicotinamide nucleotide transhydrogenas... 37 2.6
ref|YP_001518643.1| NAD(P) transhydrogenase, alpha subunit ... 37 2.7
ref|ZP_02061844.1| alanine dehydrogenase [Rickettsiella gry... 37 2.7
ref|NP_456001.1| NAD(P) transhydrogenase subunit alpha [Sal... 37 2.9
ref|NP_460439.1| NAD(P) transhydrogenase subunit alpha [Sal... 37 2.9
ref|ZP_00112137.1| COG3288: NAD/NADP transhydrogenase alpha... 37 2.9
pir||T33824 hypothetical protein W05F2.4 - Caenorhabditis e... 37 2.9
ref|NP_486395.1| alanine dehydrogenase [Nostoc sp. PCC 7120... 37 2.9
ref|YP_002754767.1| alanine dehydrogenase [Acidobacterium c... 37 3.0
ref|YP_949379.1| putative alanine dehydrogenase [Arthrobact... 37 3.1
sp|P17557|DHA_BACST Alanine dehydrogenase >gi|142455|gb|AAA... 37 3.1
>pdb|2QRJ|A Chain A, Crystal Structure Of Sulfate-Bound Saccharopine
Dehydrogenase (L-Lys Forming) From Saccharomyces
Cerevisiae
pdb|2QRK|A Chain A, Crystal Structure Of Amp-Bound Saccharopine Dehydrogenase
(L-Lys Forming) From Saccharomyces Cerevisiae
pdb|2QRL|A Chain A, Crystal Structure Of Oxalylglycine-Bound Saccharopine
Dehydrogenase (L-Lys Forming) From Saccharomyces
Cerevisiae
Length = 394
Score = 761 bits (1965), Expect = 0.0, Method: Composition-based stats.
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 22 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 81
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 82 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 141
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 142 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 201
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 202 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 261
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 262 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 321
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 322 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 381
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 382 DRHCARVKRSSRL 394
>ref|NP_012300.1| Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the
conversion of saccharopine to L-lysine, which is the
final step in the lysine biosynthesis pathway; Lys1p
[Saccharomyces cerevisiae]
sp|P38998|LYS1_YEAST Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
emb|CAA86194.1| lys1 [Saccharomyces cerevisiae]
gb|EDN61529.1| lysine requiring protein [Saccharomyces cerevisiae YJM789]
Length = 373
Score = 759 bits (1960), Expect = 0.0, Method: Composition-based stats.
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 361 DRHCARVKRSSRL 373
>emb|CAA54551.1| saccharopine dehydrogenase (NAD+, L-lysine forming) [Saccharomyces
cerevisiae]
Length = 373
Score = 758 bits (1957), Expect = 0.0, Method: Composition-based stats.
Identities = 372/373 (99%), Positives = 372/373 (99%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTT GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 301 PTVLVPTTVGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 361 DRHCARVKRSSRL 373
>pdb|2Q99|A Chain A, Crystal Structure Of Saccharopine Dehydrogenase From
Saccharomyces Cerevisiae
Length = 381
Score = 751 bits (1939), Expect = 0.0, Method: Composition-based stats.
Identities = 370/373 (99%), Positives = 370/373 (99%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 9 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 68
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKE PETDTFPLVHEHIQFAHCYKDQAGWQNVL RFIKGHGTLYD
Sbjct: 69 AGSWKTAPRDRIIIGLKEXPETDTFPLVHEHIQFAHCYKDQAGWQNVLXRFIKGHGTLYD 128
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 129 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 188
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 189 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 248
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTN EKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 249 PQADIFINCIYLSKPIAPFTNXEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 308
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 309 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 368
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 369 DRHCARVKRSSRL 381
>ref|XP_446267.1| unnamed protein product [Candida glabrata]
sp|Q6FU27|LYS1_CANGA Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
emb|CAG59191.1| unnamed protein product [Candida glabrata CBS 138]
Length = 372
Score = 627 bits (1616), Expect = e-178, Method: Composition-based stats.
Identities = 301/371 (81%), Positives = 329/371 (88%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
+VTLHLR ETKPLE RAALTPTTVK LI KGFKIYVE+SPQS F I+EYR+AGAIIVP G
Sbjct: 2 SVTLHLRGETKPLEHRAALTPTTVKHLIGKGFKIYVEESPQSIFKIDEYRRAGAIIVPFG 61
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW +APRDRIIIGLKEMPE D FPLVHEHIQFAHCYKDQAGW++VL RFI G+GTLYDLE
Sbjct: 62 SWISAPRDRIIIGLKEMPEEDKFPLVHEHIQFAHCYKDQAGWKDVLRRFINGNGTLYDLE 121
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
FLE+D GRRVAAFGFYAGFAGAALG+ DWAFKQTH D EDLPAVSPYPNEKAL+KD+ K
Sbjct: 122 FLEDDNGRRVAAFGFYAGFAGAALGLADWAFKQTHKDSEDLPAVSPYPNEKALIKDIGKA 181
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
YK AL TGA+KP VLIIGALGRCGSGAID L KVG+P+ NI+KWDI+ETSRGGPF EI
Sbjct: 182 YKNALKTGAKKPKVLIIGALGRCGSGAIDFLKKVGLPEENIIKWDIQETSRGGPFPEIAA 241
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
+DIFINCIYLSKPIAPF N E LN P+R+LRTVVDVSADTTNPHNPIPIY +ATVFNKPT
Sbjct: 242 SDIFINCIYLSKPIAPFINYELLNKPDRKLRTVVDVSADTTNPHNPIPIYNIATVFNKPT 301
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V V T++GPKLSVISIDHLPSLLPREASEFF+HDLLPSLE LP R +PVWVRA+KLF+R
Sbjct: 302 VKVNTSSGPKLSVISIDHLPSLLPREASEFFAHDLLPSLEQLPSRHVSPVWVRAEKLFNR 361
Query: 363 HCARVKRSSRL 373
H AR R S+L
Sbjct: 362 HSARAIRESKL 372
>ref|XP_454310.1| unnamed protein product [Kluyveromyces lactis]
emb|CAG99397.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
Length = 372
Score = 599 bits (1544), Expect = e-169, Method: Composition-based stats.
Identities = 283/371 (76%), Positives = 322/371 (86%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
+VTLHLRAETKPLEAR ALTPTT KKL+ KGFKI+VE+S QS F+I EY++ GA IVP G
Sbjct: 2 SVTLHLRAETKPLEARTALTPTTTKKLLDKGFKIFVEESSQSAFDIEEYKKVGATIVPEG 61
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYK+QAGW++VL RF +G+G LYDLE
Sbjct: 62 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKNQAGWEDVLSRFKRGNGVLYDLE 121
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
FLENDQGRRVAAFGFYAGFAGAA+G+RDWAFKQTHSD E+L A+ PY NE+A++KDV +D
Sbjct: 122 FLENDQGRRVAAFGFYAGFAGAAVGIRDWAFKQTHSDSENLGAIEPYENEEAMIKDVRRD 181
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
Y+ AL GARKP VLIIGALGRCGSGA DLL K G+P+ NI+KWD+KET+RGGPF EI
Sbjct: 182 YQLALKRGARKPKVLIIGALGRCGSGAADLLRKCGLPEENIIKWDMKETARGGPFQEIAD 241
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
AD+FINCIYLSKPI PF N E LN P RRLRTVVDVSADTTNPHNP+PIYT+ T F+ PT
Sbjct: 242 ADVFINCIYLSKPIPPFINNELLNKPTRRLRTVVDVSADTTNPHNPVPIYTINTTFDAPT 301
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V VPTT GPKLSV SIDHLPSLLP+EASE FS DLLPSLE LPQR TA VWV+A+ L+++
Sbjct: 302 VQVPTTVGPKLSVCSIDHLPSLLPKEASESFSRDLLPSLEQLPQRATASVWVKARNLYEK 361
Query: 363 HCARVKRSSRL 373
A+V R+S+L
Sbjct: 362 FAAKVGRTSKL 372
>ref|XP_001643683.1| hypothetical protein Kpol_1057p13 [Vanderwaltozyma polyspora DSM
70294]
gb|EDO15825.1| hypothetical protein Kpol_1057p13 [Vanderwaltozyma polyspora DSM
70294]
Length = 371
Score = 594 bits (1532), Expect = e-168, Method: Composition-based stats.
Identities = 280/369 (75%), Positives = 316/369 (85%)
Query: 5 TLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSW 64
TLHLRAETKPLEARAALTP+TVK LI KGFKIYVE+SPQS FN++EYR+ GA IVP GSW
Sbjct: 3 TLHLRAETKPLEARAALTPSTVKSLIKKGFKIYVEESPQSVFNVDEYRRCGATIVPFGSW 62
Query: 65 KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFL 124
+APRDRIIIGLKEMPE D FPLVH+HIQFAHCYKDQ GW+ VL RFI G GTLYDLEFL
Sbjct: 63 ISAPRDRIIIGLKEMPEEDVFPLVHDHIQFAHCYKDQEGWEKVLRRFINGQGTLYDLEFL 122
Query: 125 ENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYK 184
E+D G+RVAAFGFYAGFAGAALG++DWAFK+TH D EDL A++PYPNEKAL++D++ +YK
Sbjct: 123 EDDNGKRVAAFGFYAGFAGAALGLKDWAFKKTHDDSEDLGALTPYPNEKALLRDISHEYK 182
Query: 185 EALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQAD 244
+AL TGA+ P VLIIGALGRCGSGAID L K+GIP NI+KWD++ET++GGPF EI D
Sbjct: 183 QALKTGAKAPKVLIIGALGRCGSGAIDFLTKIGIPQENIIKWDMQETAKGGPFQEIVDTD 242
Query: 245 IFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPTVL 304
IF+NCIYLSKPI PF NM LN +R L TVVDVSADTTNP+NPIPIY +ATVFNKPTV
Sbjct: 243 IFVNCIYLSKPIPPFVNMSMLNQDSRHLTTVVDVSADTTNPYNPIPIYNIATVFNKPTVT 302
Query: 305 VPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDRHC 364
VPT GPKLSVISIDHLPSL+PREASE F+ DLLPSLELLP R APVW RA LF+RH
Sbjct: 303 VPTKKGPKLSVISIDHLPSLMPREASEAFAKDLLPSLELLPNRHVAPVWTRAYSLFNRHS 362
Query: 365 ARVKRSSRL 373
AR RSS+L
Sbjct: 363 ARAYRSSKL 371
>ref|XP_001387327.1| Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH) [Pichia
stipitis CBS 6054]
gb|EAZ63304.1| Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH) [Pichia
stipitis CBS 6054]
Length = 371
Score = 567 bits (1461), Expect = e-160, Method: Composition-based stats.
Identities = 271/365 (74%), Positives = 307/365 (84%), Gaps = 1/365 (0%)
Query: 4 VTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGS 63
V LHLRAETKPLE RAALTPTT K+LI GFKI+VE S QSTF I EY QAGA IVP GS
Sbjct: 5 VILHLRAETKPLEHRAALTPTTTKQLIDAGFKIFVEKSSQSTFAIEEYEQAGATIVPEGS 64
Query: 64 WKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEF 123
WK AP+DRIIIGLKE+PE +TFPLVHEHIQFAHCYKDQ GW++VL RF G+GTLYDLEF
Sbjct: 65 WKEAPKDRIIIGLKELPEDETFPLVHEHIQFAHCYKDQGGWKDVLSRFPAGNGTLYDLEF 124
Query: 124 LENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDY 183
LEND GRRVAAFGFYAGFAGAA+GVRDWAFKQ H D E+L ++PYPNE L+ DV KD
Sbjct: 125 LENDTGRRVAAFGFYAGFAGAAIGVRDWAFKQLHPDSENLGGLTPYPNEDGLIADVKKDL 184
Query: 184 KEAL-ATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
+ AL G + PT L+IGALGRCGSGAIDL KVGIP+ NI KWDI+ET++GGPF EI +
Sbjct: 185 EAALQKNGGQYPTTLVIGALGRCGSGAIDLFRKVGIPEENITKWDIQETAKGGPFKEIVE 244
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
+DIF+NCIYLS+PI PF + LN P+R+LR +VDVSADTTNPHNPIP+Y++ATVFN PT
Sbjct: 245 SDIFVNCIYLSQPIPPFIDYSSLNVPDRKLRIIVDVSADTTNPHNPIPVYSIATVFNDPT 304
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V+V TTAGPKLSV SIDHLPSLLPREASEFFS DLLPSL LP+R+TAPVW RAK LFD+
Sbjct: 305 VVVETTAGPKLSVCSIDHLPSLLPREASEFFSRDLLPSLLQLPERQTAPVWTRAKALFDK 364
Query: 363 HCARV 367
H AR+
Sbjct: 365 HVARL 369
>ref|XP_001523078.1| saccharopine dehydrogenase [Lodderomyces elongisporus NRRL YB-4239]
gb|EDK47443.1| saccharopine dehydrogenase [Lodderomyces elongisporus NRRL YB-4239]
Length = 370
Score = 567 bits (1461), Expect = e-160, Method: Composition-based stats.
Identities = 273/365 (74%), Positives = 306/365 (83%), Gaps = 1/365 (0%)
Query: 4 VTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGS 63
V LHLRAETKPLEARAALTPTT K+L+ GFK+YVE+S QSTFN EY GA IVP GS
Sbjct: 6 VILHLRAETKPLEARAALTPTTTKQLLDAGFKVYVEESSQSTFNAKEYEAVGAEIVPEGS 65
Query: 64 WKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEF 123
WK AP+DRII GLKE+PE DTFPLVH HIQFAHCYK+QAGW+ VL RF G+GTLYDLEF
Sbjct: 66 WKDAPKDRIIFGLKELPENDTFPLVHTHIQFAHCYKNQAGWEKVLGRFPAGNGTLYDLEF 125
Query: 124 LENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDY 183
LENDQGRRVAAFGFYAGFAGAA+GV DWAFKQ H DDE+LP VSPYPNE AL+KDV +
Sbjct: 126 LENDQGRRVAAFGFYAGFAGAAIGVLDWAFKQLHGDDENLPGVSPYPNEDALIKDVKTEL 185
Query: 184 KEALA-TGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
+ALA G + PT L+IGALGRCGSGAIDL KVGIPD N+ KWD+ ET++GGPF EI
Sbjct: 186 DKALAKNGGKYPTALVIGALGRCGSGAIDLFKKVGIPDDNVAKWDMAETAKGGPFKEIVD 245
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
+IF+NCIYLS+PIAPF N E LN P R+L T+VDVSADTTNPHNPIP+Y +ATVFN PT
Sbjct: 246 TNIFVNCIYLSQPIAPFINYETLNVPERKLTTIVDVSADTTNPHNPIPVYEIATVFNDPT 305
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V V TTAGPKLSV SIDHLPSLLPREASEFFS DL+PSL LP+R TAPVWVRAK+LFD+
Sbjct: 306 VPVKTTAGPKLSVCSIDHLPSLLPREASEFFSKDLMPSLLQLPERDTAPVWVRAKQLFDK 365
Query: 363 HCARV 367
+ AR+
Sbjct: 366 NVARL 370
>ref|XP_457987.1| hypothetical protein DEHA0C07832g [Debaryomyces hansenii CBS767]
emb|CAG86045.1| unnamed protein product [Debaryomyces hansenii CBS767]
Length = 370
Score = 565 bits (1455), Expect = e-159, Method: Composition-based stats.
Identities = 267/367 (72%), Positives = 309/367 (84%), Gaps = 1/367 (0%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
+ VTLHLRAETKPLEARAALTP+T K+L+ GFK+YVE S QSTF+ +EY + GA IVP
Sbjct: 3 SPVTLHLRAETKPLEARAALTPSTTKQLLDAGFKVYVEKSSQSTFDADEYEKVGATIVPE 62
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWK AP+DRII GLKE+PE +TFPLVHEHIQFAHCYKDQ GW++VL RF +G GTLYDL
Sbjct: 63 GSWKEAPKDRIIFGLKELPEDETFPLVHEHIQFAHCYKDQGGWKDVLRRFPEGKGTLYDL 122
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
EFLENDQGRRVAAFGFYAGFAGAA+GV DWAFKQTHSD+EDL V+PYPNE L+ DV K
Sbjct: 123 EFLENDQGRRVAAFGFYAGFAGAAIGVMDWAFKQTHSDNEDLRGVTPYPNEDELIADVKK 182
Query: 182 DYKEAL-ATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
EAL G P L+IGALGRCGSGA+D KVGIPD ++KWD+KET++GGPF EI
Sbjct: 183 VLDEALKKNGGEYPQCLVIGALGRCGSGALDFFKKVGIPDEKLIKWDMKETAKGGPFQEI 242
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
Q+DIF+NCIYLS+PI PF + E LN P+R+LRT+VDVSADTTNPHNPIP+Y++ATVFN
Sbjct: 243 VQSDIFVNCIYLSQPIPPFIDYEGLNVPDRKLRTIVDVSADTTNPHNPIPVYSIATVFND 302
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTV V T+AGPKLSV SIDHLPSLLPREASEFF+ DL+PSL LP R T+PVWVRAK+LF
Sbjct: 303 PTVPVETSAGPKLSVCSIDHLPSLLPREASEFFAKDLMPSLLELPNRDTSPVWVRAKQLF 362
Query: 361 DRHCARV 367
D+H AR+
Sbjct: 363 DKHVARL 369
>ref|NP_983569.1| ACR167Cp [Ashbya gossypii ATCC 10895]
sp|Q75BV4|LYS1_ASHGO Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAS51393.1| ACR167Cp [Ashbya gossypii ATCC 10895]
Length = 372
Score = 548 bits (1413), Expect = e-154, Method: Composition-based stats.
Identities = 263/373 (70%), Positives = 316/373 (84%), Gaps = 1/373 (0%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M+A+ LHLRAETKP+EARAALTPTTV+ L++ GFKIYVE+S QS F EY AGA +V
Sbjct: 1 MSAI-LHLRAETKPMEARAALTPTTVRTLVSHGFKIYVEESAQSVFEAAEYAAAGAEVVA 59
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW+ APR+RII+GLKE+PE DTFPL H HIQFAHCYK+Q+GW+ VL RF G G LYD
Sbjct: 60 TGSWRGAPRERIIVGLKELPEEDTFPLEHTHIQFAHCYKNQSGWREVLGRFQSGGGLLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL++D+GRRVAAFG+YAGFAGAALG+RDWA+KQTH+D EDLPAV+PY NE+ALV +V
Sbjct: 120 LEFLQDDRGRRVAAFGYYAGFAGAALGLRDWAWKQTHTDAEDLPAVAPYENEQALVSEVA 179
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
+EA GARKP VL+IGALGRCGSGA++LL + G+ D +I++WDI ET+RGGPF EI
Sbjct: 180 AACEEAYKKGARKPRVLVIGALGRCGSGAVELLRQCGLHDKHIIRWDIAETARGGPFPEI 239
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
ADIFINCIYLS+PIAPF NME L+ P+R+LRT+VDVSADTTNPHNP+P+Y VATVF+
Sbjct: 240 AAADIFINCIYLSQPIAPFINMELLDRPDRKLRTIVDVSADTTNPHNPVPVYNVATVFSS 299
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTV+VPT+ GPKLSVISIDHLPSLLPREASE F+ DLLPSL LP+R TAPVW+RAK+LF
Sbjct: 300 PTVVVPTSQGPKLSVISIDHLPSLLPREASEAFASDLLPSLLQLPERDTAPVWLRAKELF 359
Query: 361 DRHCARVKRSSRL 373
+HC R+ + +RL
Sbjct: 360 QQHCERLSKEARL 372
>sp|P43065|LYS1_CANAL Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAA21362.1| saccharopine dehydrogenase
Length = 382
Score = 546 bits (1406), Expect = e-153, Method: Composition-based stats.
Identities = 262/378 (69%), Positives = 306/378 (80%), Gaps = 10/378 (2%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
+ V LHLRAETKPLEARAALTP+T K+L+ GF+IYVE+S QSTF+I EY GA IVP
Sbjct: 4 SPVILHLRAETKPLEARAALTPSTTKQLLDAGFEIYVEESSQSTFDIKEYEAVGAKIVPE 63
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWKTAP++RII GLKE+PE +TFPL+HEHIQFAHCYKDQAGWQ+VL RF +G+G LYDL
Sbjct: 64 GSWKTAPKERIIFGLKELPENETFPLIHEHIQFAHCYKDQAGWQDVLKRFPQGNGILYDL 123
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDED---------LPAVSPYPNE 172
EFLENDQGRRVAAFGFYAGFAGAA+GV DW+FKQ + + + LP V+PYPNE
Sbjct: 124 EFLENDQGRRVAAFGFYAGFAGAAIGVLDWSFKQLNGNTKGTKGEGEGGELPGVTPYPNE 183
Query: 173 KALVKDVTKDYKEALA-TGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKET 231
L+KDV + ++AL G + P L+IGALGRCGSGAIDL K+GIPD NI KWD+ ET
Sbjct: 184 NELIKDVKIELEKALTKNGGQYPKCLVIGALGRCGSGAIDLFKKIGIPDDNIAKWDMAET 243
Query: 232 SRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPI 291
++GGPF EI +DIFINCIYLSKPI PF N E LNN NR+L T+VDVSADTTNPHNPIP+
Sbjct: 244 AKGGPFQEIVDSDIFINCIYLSKPIPPFINKEILNNENRKLTTIVDVSADTTNPHNPIPV 303
Query: 292 YTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAP 351
Y +ATVFN+PTV V GPKLSV SIDHLPSLLPREASEFF+ DL+PSL LP R T+P
Sbjct: 304 YEIATVFNEPTVEVKLDKGPKLSVCSIDHLPSLLPREASEFFAKDLMPSLLELPNRDTSP 363
Query: 352 VWVRAKKLFDRHCARVKR 369
VWVRAK+LFD+H AR+ +
Sbjct: 364 VWVRAKQLFDKHVARLDK 381
>ref|XP_001482345.1| hypothetical protein PGUG_05365 [Pichia guilliermondii ATCC 6260]
gb|EDK41267.1| hypothetical protein PGUG_05365 [Pichia guilliermondii ATCC 6260]
Length = 370
Score = 533 bits (1372), Expect = e-149, Method: Composition-based stats.
Identities = 254/367 (69%), Positives = 304/367 (82%), Gaps = 1/367 (0%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
A V+LHLRAETKPLEARA L+P+ K+L+ GFK+YVE S QSTF+ +EY + GA IVP
Sbjct: 3 APVSLHLRAETKPLEARAGLSPSVTKELLDAGFKVYVEKSSQSTFDADEYAKVGAEIVPE 62
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWK AP+DRII GLK +PE +TFPLVHEHIQFAHCYKDQAGW++VL RF G+GTLYDL
Sbjct: 63 GSWKEAPKDRIIYGLKALPEDETFPLVHEHIQFAHCYKDQAGWKDVLSRFPAGNGTLYDL 122
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
EFL ND+GRRVAAFGFYAGFAGAA+G++DWAFKQTH+D+E+L V+PY E+ L+KDV +
Sbjct: 123 EFLVNDEGRRVAAFGFYAGFAGAAIGLKDWAFKQTHADNEELRGVTPYATEEELIKDVKE 182
Query: 182 DYKEALA-TGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
D ALA G + P L+IGALGRCGSGA+ L K GIPD IL+WD+KET+RGGPF+EI
Sbjct: 183 DLDAALAKNGGKYPQCLVIGALGRCGSGAVSLFKKAGIPDEKILQWDMKETARGGPFEEI 242
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+DIFINCIYLS+PI PF + E LN+ R+LRT+VDVSADTTNP+NPIP+YTV T F+K
Sbjct: 243 TDSDIFINCIYLSQPIPPFVSSETLNSEKRKLRTIVDVSADTTNPNNPIPVYTVITDFDK 302
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PT LV TTAGPKLSV SIDHLPSL+PREASE F+ DLLP+L LP R TAPV+ RAK+LF
Sbjct: 303 PTALVETTAGPKLSVCSIDHLPSLVPREASETFAKDLLPTLLQLPDRNTAPVYQRAKQLF 362
Query: 361 DRHCARV 367
++H AR+
Sbjct: 363 EKHVARL 369
>ref|XP_500931.1| YlLYS5 [Yarrowia lipolytica]
sp|P38997|LYS1_YARLI Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAA35248.1| saccharopine dehydrogenase
emb|CAG83182.1| YlLYS5 [Yarrowia lipolytica CLIB122]
Length = 369
Score = 498 bits (1283), Expect = e-139, Method: Composition-based stats.
Identities = 248/366 (67%), Positives = 290/366 (79%), Gaps = 1/366 (0%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
A V LHLRAETKPLE R+ALTPTT +KL+ GF+++VE SP F+ E+ GA +V
Sbjct: 3 APVKLHLRAETKPLEHRSALTPTTTRKLLDAGFEVFVEKSPLRIFDDQEFVDVGATLVEE 62
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSW +AP DR+IIGLKE+PE ++FPL HEHIQFAHCYKDQ GW++VL RF G+GTLYDL
Sbjct: 63 GSWVSAPEDRMIIGLKELPE-ESFPLSHEHIQFAHCYKDQGGWKDVLSRFPAGNGTLYDL 121
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
EFLE+D GRRVAAFGF+AGFAGAA+GV WAF+QTH D E+LP VS YPNE LV + K
Sbjct: 122 EFLEDDNGRRVAAFGFHAGFAGAAIGVETWAFQQTHPDSENLPGVSAYPNETELVDKIKK 181
Query: 182 DYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIP 241
D A+ G++ PTVL+IGALGRCGSGAIDL KVGIP+ NI++WD+ ET +GGPF EI
Sbjct: 182 DLAAAVEKGSKLPTVLVIGALGRCGSGAIDLARKVGIPEENIIRWDMNETKKGGPFQEIA 241
Query: 242 QADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKP 301
ADIFINCIYLS+PI PF N + LN R+L +VDVSADTTNPHNP+P+YT+AT F+ P
Sbjct: 242 DADIFINCIYLSQPIPPFINYDLLNKETRKLSVIVDVSADTTNPHNPVPVYTIATTFDHP 301
Query: 302 TVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFD 361
TV V TTAGPKLSV SIDHLPSLLPREASE FS LLPSL LPQR TAPVW RAK LFD
Sbjct: 302 TVPVETTAGPKLSVCSIDHLPSLLPREASEAFSEALLPSLLQLPQRDTAPVWTRAKALFD 361
Query: 362 RHCARV 367
+H R+
Sbjct: 362 KHVLRI 367
>ref|XP_964977.1| saccharopine dehydrogenase [Neurospora crassa OR74A]
sp|Q7SFX6|LYS1_NEUCR Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|EAA35741.1| saccharopine dehydrogenase [Neurospora crassa OR74A]
Length = 372
Score = 426 bits (1094), Expect = e-117, Method: Composition-based stats.
Identities = 225/372 (60%), Positives = 270/372 (72%), Gaps = 4/372 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MA LHLR+ETK LE R+ALTPTT +LI G+ + VE SP+ F+ E+ +AGA +VP
Sbjct: 1 MAPTVLHLRSETKHLEHRSALTPTTTAELIKAGYIVNVERSPERIFDDEEFEKAGATLVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
SW AP++ II+GLKE+ E D FPL H H+QFAHCYK QAGW+NVL RF +G GTL D
Sbjct: 61 EHSWVDAPKEHIIVGLKELEEKD-FPLKHVHVQFAHCYKQQAGWENVLARFPRGGGTLLD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL ++ GRRVAAFGF+AGFAGAAL + WA++ HS E P V YPNE AL+ DV
Sbjct: 120 LEFLVDEHGRRVAAFGFHAGFAGAALALEVWAWQLNHS--EPFPGVESYPNEDALIADVK 177
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K KE + R P V++IGA GRCGSGA+ L K GIPD NIL WD+ ET++GGPF EI
Sbjct: 178 KAVKEGVEAAGRLPRVIVIGARGRCGSGAVSALKKAGIPDENILDWDMAETAKGGPFKEI 237
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+DIF+NCIYL+ I F NME L P+R+LR V DVSADTT+P P+PIYTVAT F+K
Sbjct: 238 TDSDIFVNCIYLTSKIPNFVNMESLQVPDRQLRVVCDVSADTTSPFTPVPIYTVATTFDK 297
Query: 301 PTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
PTV V T+GP LSVISIDHLPSLLPREASE FSHDLLPSL L + +PVW RAK+L
Sbjct: 298 PTVPVDGLTSGPPLSVISIDHLPSLLPREASEAFSHDLLPSLLTLNDWQNSPVWARAKQL 357
Query: 360 FDRHCARVKRSS 371
FD A + S+
Sbjct: 358 FDEKVATLPESA 369
>ref|NP_592972.1| saccharopine dehydrogenase [NAD+, L-lysine forming] (PMID 3142867)
[Schizosaccharomyces pombe]
sp|Q09694|LYS1_SCHPO Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
emb|CAB61467.1| saccharopine dehydrogenase [NAD+, L-lysine forming] (PMID 3142867)
[Schizosaccharomyces pombe]
Length = 368
Score = 424 bits (1089), Expect = e-117, Method: Composition-based stats.
Identities = 213/363 (58%), Positives = 259/363 (71%), Gaps = 3/363 (0%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M A L LRAETKPLE R+ALTP T K L GF+I +E S Q F E+ + G +VP
Sbjct: 1 MVAPHLWLRAETKPLEERSALTPRTAKILADAGFQITIERSSQRAFKDKEFERLGFPMVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW+ AP+D IIGLKE+PE D PL H HIQFAHCYK+Q GW+ VL RF G+G LYD
Sbjct: 61 EGSWRHAPKDAYIIGLKELPENDNSPLKHTHIQFAHCYKNQEGWREVLSRFPAGNGLLYD 120
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL++D GRRVAAFG++AGFAG+A+ WA + H + + PA+ P+PNEK+LV+ V
Sbjct: 121 LEFLQDDNGRRVAAFGYHAGFAGSAISCLVWAHQLLHPNKQ-FPAIRPFPNEKSLVRHVA 179
Query: 181 KDYKEALATGARK-PTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + AL + P +L+IGALGRCG+GA DL K+GIP NIL+WDI ET +GGPF E
Sbjct: 180 RQVRLALKKNNNQYPRILVIGALGRCGTGACDLASKIGIPFDNILRWDINETKKGGPFTE 239
Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
I ++DIF+NCIYLS PI F +E LN PNR+LR V DVS DTTNP+NPIPIY V T F+
Sbjct: 240 ITESDIFVNCIYLSMPIPKFCTVESLNVPNRKLRVVCDVSCDTTNPNNPIPIYNVNTTFD 299
Query: 300 KPTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKK 358
PTV V T P L VISIDHLP+LLPRE+SE FS L+PSL L APVWVRAKK
Sbjct: 300 HPTVEVKGVTTPPPLEVISIDHLPTLLPRESSEAFSEALIPSLLALKDVDNAPVWVRAKK 359
Query: 359 LFD 361
L++
Sbjct: 360 LYE 362
>ref|XP_001908761.1| unnamed protein product [Podospora anserina]
emb|CAP69434.1| unnamed protein product [Podospora anserina]
Length = 374
Score = 420 bits (1079), Expect = e-115, Method: Composition-based stats.
Identities = 219/372 (58%), Positives = 270/372 (72%), Gaps = 2/372 (0%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MA LHLR+ETKPLE R+ALTPTT LI G+ + VE SP+ F+ +E+ GA +VP
Sbjct: 1 MAPTVLHLRSETKPLEHRSALTPTTTAALIKAGYVVNVERSPERIFDDSEFEAVGATLVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW+ P++ II+GLKE+ E + FPL H H+QFAHCYK QAGW+NVL RF +G GTL D
Sbjct: 61 EGSWEEVPKEHIIVGLKELEEKE-FPLKHVHVQFAHCYKHQAGWENVLARFPRGGGTLLD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL +++GRRVAAFGF+AGFAGAAL + WA + TH P V+ YPNE AL+ +V
Sbjct: 120 LEFLVDERGRRVAAFGFHAGFAGAALALEVWAHQLTHPPSSPFPGVASYPNEDALITNVK 179
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K A R P V++IGALGRCGSGA+D L K G+P+ NILKWD+ ET++GGPF EI
Sbjct: 180 KALATGTAAAGRSPRVIVIGALGRCGSGAVDALRKAGVPEENILKWDMAETAKGGPFKEI 239
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+DIF+NCIYL+ I F N++ L P+R+L V DVSADTT+P P+PIYTVAT F+K
Sbjct: 240 TDSDIFVNCIYLTSKIPNFVNLDSLQVPDRKLSVVCDVSADTTSPFTPVPIYTVATTFDK 299
Query: 301 PTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
PTV V ++GP LSVISIDHLPSLLPREASE FSHDLLPSL L + +PVW RAKKL
Sbjct: 300 PTVPVEGLSSGPALSVISIDHLPSLLPREASEAFSHDLLPSLLTLNDWQNSPVWARAKKL 359
Query: 360 FDRHCARVKRSS 371
FD A + S+
Sbjct: 360 FDEKVATLPASA 371
>ref|XP_001593244.1| saccharopine dehydrogenase [Sclerotinia sclerotiorum 1980]
gb|EDO03685.1| saccharopine dehydrogenase [Sclerotinia sclerotiorum 1980]
Length = 372
Score = 419 bits (1077), Expect = e-115, Method: Composition-based stats.
Identities = 217/370 (58%), Positives = 266/370 (71%), Gaps = 2/370 (0%)
Query: 1 MAAVTLHLRAET-KPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIV 59
M+ TLHLR+E K LE R+ALTPTT K LI G+ I VE SP+ F+ E+ + GA +V
Sbjct: 1 MSGTTLHLRSELGKALEHRSALTPTTAKALIDAGYTINVERSPERIFDDEEFEKVGATLV 60
Query: 60 PAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
P +W+ AP+D IIIGLKE+P D FPL H H+QFAHCYK Q GW VL RF +G GTL
Sbjct: 61 PEDTWRQAPKDHIIIGLKELPVED-FPLEHVHVQFAHCYKQQGGWDTVLSRFPRGGGTLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D+GRRVAAFG++AGFAGAAL + WA++ THS E P+VS YPNE L+ DV
Sbjct: 120 DLEFLTDDKGRRVAAFGYHAGFAGAALALETWAWQLTHSASEPFPSVSSYPNEDELIADV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
K + P VL+IGALGRCGSGA+DL + G+P N+LKWD+ ET++GGPF E
Sbjct: 180 KKAIAAGQEKTGKAPRVLVIGALGRCGSGAVDLCLRAGVPTENVLKWDMAETAKGGPFPE 239
Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
I ++DIFINCIYL I F +M+ L+ PNR+L V DVSADTTNP+NPIPIYTVAT F+
Sbjct: 240 IVESDIFINCIYLMSKIPNFVDMQSLDTPNRKLSVVCDVSADTTNPNNPIPIYTVATTFS 299
Query: 300 KPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
+PTV V P+LSVISIDHLPSLLPREASE FS DLLPSL L ++ PVW +A+KL
Sbjct: 300 EPTVPVEVKGDPRLSVISIDHLPSLLPREASEAFSKDLLPSLLTLKDWRSTPVWAKAEKL 359
Query: 360 FDRHCARVKR 369
F A + +
Sbjct: 360 FQEKVATLPK 369
>gb|EDU47954.1| saccharopine dehydrogenase [Pyrenophora tritici-repentis Pt-1C-BFP]
Length = 387
Score = 417 bits (1072), Expect = e-115, Method: Composition-based stats.
Identities = 213/374 (56%), Positives = 262/374 (70%), Gaps = 17/374 (4%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQS-----TFNINEYRQAG 55
MA TLH RAE KPLE R+ LTPTT KKL+ G+ + VE SP+ F +E+ + G
Sbjct: 1 MAFPTLHARAEAKPLEHRSCLTPTTAKKLLDAGYPVLVERSPKDPNYARIFKDDEFEEVG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A ++ G++KTAP+DRIIIGLKE+PE D FPL H + FAHCYK Q GW+NVL RF +G
Sbjct: 61 ATLIEEGAYKTAPKDRIIIGLKELPE-DKFPLEHTFVHFAHCYKQQGGWENVLARFPRGG 119
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
GTLYDLEFL+++ GRRVAAFG++AGF GAAL ++ WA++ TH + E LP +
Sbjct: 120 GTLYDLEFLQDESGRRVAAFGYHAGFVGAALAIKTWAWQLTHPNGEPLPGLETFTEGRGY 179
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE L+ + +D KP+ L++GALGRCGSGA+DLL K+G P+ I KWD+
Sbjct: 180 YNNESELITQLKEDVAAGEKIAGHKPSSLVLGALGRCGSGAVDLLEKIGCPE--IKKWDL 237
Query: 229 KET-SRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHN 287
ET R GP+ EI ++DIF+NCIYLSKPI PF N E L +PNRRL V DVS DTTNPHN
Sbjct: 238 AETKERDGPYPEIVESDIFVNCIYLSKPIPPFVNKESLKSPNRRLSVVCDVSCDTTNPHN 297
Query: 288 PIPIYTVATVFNKPTVLVPTTA-GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQ 346
PIPIY + T F+KPTV V GP+LSVISIDHLPS LPRE+SE FS+ LLPSL L
Sbjct: 298 PIPIYDINTTFDKPTVEVSVEGDGPRLSVISIDHLPSALPRESSEAFSNALLPSLMALKD 357
Query: 347 RKTAPVWVRAKKLF 360
R T PVW A+KLF
Sbjct: 358 RATTPVWQGAEKLF 371
>ref|XP_001559795.1| saccharopine dehydrogenase [Botryotinia fuckeliana B05.10]
gb|EDN27084.1| saccharopine dehydrogenase [Botryotinia fuckeliana B05.10]
Length = 372
Score = 416 bits (1069), Expect = e-114, Method: Composition-based stats.
Identities = 215/371 (57%), Positives = 266/371 (71%), Gaps = 2/371 (0%)
Query: 1 MAAVTLHLRAET-KPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIV 59
M+ TLHLR+E K LE R+ALTPTT K LI G+ I VE SP+ F+ E+ + GA +V
Sbjct: 1 MSGTTLHLRSELGKALEHRSALTPTTAKALIDAGYTINVERSPERIFDDEEFEKVGATLV 60
Query: 60 PAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
P +W+ AP+D IIIGLKE+P + FPL H H+QFAHCYK Q GW VL RF +G GTL
Sbjct: 61 PENTWRQAPKDHIIIGLKELP-VEEFPLEHVHVQFAHCYKQQGGWDTVLSRFPRGGGTLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D+GRRVAAFG++AGFAGAAL + +WA++ TH E P+VS YPNE L+ DV
Sbjct: 120 DLEFLTDDRGRRVAAFGYHAGFAGAALALENWAWQLTHPASEPFPSVSSYPNEDELIVDV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
K + P VL+IGALGRCGSGA+DL + G+P N+LKWD+ ET++GGPF E
Sbjct: 180 KKAIAAGQEKTGKAPRVLVIGALGRCGSGAVDLCLRAGVPTENVLKWDMAETAKGGPFPE 239
Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
I ++DIFINCIYL I F +M+ L+ PNR+L V DVSADTTNP+NPIPIYTVAT F+
Sbjct: 240 IVESDIFINCIYLMSKIPNFVDMQSLDTPNRKLSVVCDVSADTTNPNNPIPIYTVATTFS 299
Query: 300 KPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
+PTV V P+LSVISIDHLPSLLPREASE FS DLLPSL L + PVW +A+KL
Sbjct: 300 EPTVPVEVKGEPRLSVISIDHLPSLLPREASEAFSKDLLPSLLSLKDWRNTPVWAKAEKL 359
Query: 360 FDRHCARVKRS 370
F A + ++
Sbjct: 360 FQEKVATLPKN 370
>ref|XP_711455.1| saccharopine dehydrogenase [Candida albicans SC5314]
gb|EAK92210.1| hypothetical protein CaO19.1790 [Candida albicans SC5314]
gb|EAK92227.1| hypothetical protein CaO19.9356 [Candida albicans SC5314]
Length = 292
Score = 415 bits (1066), Expect = e-114, Method: Composition-based stats.
Identities = 197/289 (68%), Positives = 231/289 (79%), Gaps = 10/289 (3%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
+ V LHLRAETKPLEARAALTP+T K+L+ GF+IYVE+S QSTF+I EY GA IVP
Sbjct: 4 SPVILHLRAETKPLEARAALTPSTTKQLLDAGFEIYVEESSQSTFDIKEYEAVGAKIVPE 63
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWKTAP++RII GLKE+PE +TFPL+HEHIQFAHCYKDQAGWQ+VL RF +G+G LYDL
Sbjct: 64 GSWKTAPKERIIFGLKELPENETFPLIHEHIQFAHCYKDQAGWQDVLKRFPQGNGILYDL 123
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSD---------DEDLPAVSPYPNE 172
EFLENDQGRRVAAFGFYAGFAGAA+GV DW+FKQ + + +LP V+PYPNE
Sbjct: 124 EFLENDQGRRVAAFGFYAGFAGAAIGVLDWSFKQLNGNTKGTKGEGEGGELPGVTPYPNE 183
Query: 173 KALVKDVTKDYKEALA-TGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKET 231
L+KDV + ++AL G + P L+IGALGRCGSGAIDL K+GIPD NI KWD+ ET
Sbjct: 184 NELIKDVKIELEKALTKNGGQYPKCLVIGALGRCGSGAIDLFKKIGIPDDNIAKWDMAET 243
Query: 232 SRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSA 280
++GGPF EI +DIFINCIYLSKPI PF N E LNN NR+L T+VDVSA
Sbjct: 244 AKGGPFQEIVDSDIFINCIYLSKPIPPFINKEILNNENRKLTTIVDVSA 292
>ref|XP_001213891.1| hypothetical protein ATEG_04713 [Aspergillus terreus NIH2624]
gb|EAU35160.1| hypothetical protein ATEG_04713 [Aspergillus terreus NIH2624]
Length = 988
Score = 413 bits (1061), Expect = e-113, Method: Composition-based stats.
Identities = 213/377 (56%), Positives = 265/377 (70%), Gaps = 6/377 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M + + LRAETKP EAR+ALTPTT K LI G+ + VE S Q F +E+ + GA +V
Sbjct: 612 MPSNKIWLRAETKPAEARSALTPTTAKALIDAGYDVTVERSKQRIFEDDEFPKIGAKLVE 671
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK Q GW+ VL R+ +G GTL
Sbjct: 672 EGSWVKDAPKDAFILGLKELPEDD-FPLEHVHISFAHCYKQQGGWEKVLSRWPRGGGTLL 730
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP PY N+ L++ V
Sbjct: 731 DLEFLTDDAGRRVAAFGYSAGYAGSALAVKNWAWQLTHPEGEPLPGEVPYANQDLLIQSV 790
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + R P VL+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 791 KESLEAGKKASGRSPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDMEETKKGGPFRE 850
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIF+NCIYLS PI PF N E L++PNRRL + DVSADTTNPHNPIP+YTV T F
Sbjct: 851 IIEDADIFVNCIYLSSPIPPFLNGETLSSPNRRLSVICDVSADTTNPHNPIPVYTVTTTF 910
Query: 299 NKPTV---LVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
++PTV L T GP LSVISIDHLPSLLPRE+SE FS LLPSL L + A VW +
Sbjct: 911 DRPTVPVILPAGTQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDWQNARVWKQ 970
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF A + S R
Sbjct: 971 AEDLFKEKVATLPESMR 987
>ref|XP_754450.1| saccharopine dehydrogenase Lys1 [Aspergillus fumigatus Af293]
gb|EAL92412.1| saccharopine dehydrogenase Lys1, putative [Aspergillus fumigatus
Af293]
gb|EDP52582.1| saccharopine dehydrogenase Lys1, putative [Aspergillus fumigatus
A1163]
Length = 374
Score = 412 bits (1060), Expect = e-113, Method: Composition-based stats.
Identities = 212/377 (56%), Positives = 269/377 (71%), Gaps = 9/377 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F++ Q GA +V
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSRQRIFDV---VQIGAPLVE 57
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK QAGW+ VL R+ +G GTL
Sbjct: 58 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQAGWEKVLSRWPRGGGTLL 116
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL ++ GRRVAAFG+ AG+AG+AL +++WA++ TH + E LP +PY N+ L++ V
Sbjct: 117 DLEFLTDETGRRVAAFGYSAGYAGSALAIKNWAWQLTHPEGEPLPGETPYANQDLLIESV 176
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + R P VL+IGALGRCG GA+ L VGIP+++I++WDI+ET +GGPF E
Sbjct: 177 KESLESGKKLSGRPPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDIEETKKGGPFRE 236
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIFINCIYLS I PF N E L++PNRRL + DVSADTTNP+NPIP+Y++ T F
Sbjct: 237 IVEDADIFINCIYLSAKIPPFVNTETLSSPNRRLSVICDVSADTTNPNNPIPVYSITTTF 296
Query: 299 NKPTVLVP---TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV VP GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A VW +
Sbjct: 297 DKPTVTVPLPELAQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDRKNARVWKQ 356
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF+ A + S R
Sbjct: 357 AEDLFNEKVATLPESMR 373
>ref|XP_001263295.1| saccharopine dehydrogenase Lys1, putative [Neosartorya fischeri
NRRL 181]
gb|EAW21398.1| saccharopine dehydrogenase Lys1, putative [Neosartorya fischeri
NRRL 181]
Length = 374
Score = 412 bits (1059), Expect = e-113, Method: Composition-based stats.
Identities = 211/377 (55%), Positives = 269/377 (71%), Gaps = 9/377 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F++ Q GA +V
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSTQRIFDV---VQIGAPLVE 57
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK QAGW+ VL R+ +G GTL
Sbjct: 58 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQAGWEKVLSRWPRGGGTLL 116
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFG+ AG+AG+AL +++WA++ TH + E LP +PY N+ L++ V
Sbjct: 117 DLEFLTDDTGRRVAAFGYSAGYAGSALAIKNWAWQLTHPEGEPLPGETPYANQDLLIESV 176
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + R P VL+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 177 KESLESGKKLSGRPPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDLEETKKGGPFRE 236
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIFINCIYLS I PF N E L++P RRL + DVSADTTNP+NPIP+Y++ T F
Sbjct: 237 IVEDADIFINCIYLSAKIPPFVNTETLSSPKRRLSVICDVSADTTNPNNPIPVYSITTTF 296
Query: 299 NKPTVLVPTT---AGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV VP + GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A VW +
Sbjct: 297 DKPTVTVPLSERAQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDRKNARVWEQ 356
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF+ A + S R
Sbjct: 357 AEDLFNEKVATLPESIR 373
>ref|XP_001803532.1| hypothetical protein SNOG_13323 [Phaeosphaeria nodorum SN15]
gb|EAT79207.1| hypothetical protein SNOG_13323 [Phaeosphaeria nodorum SN15]
Length = 387
Score = 412 bits (1058), Expect = e-113, Method: Composition-based stats.
Identities = 213/374 (56%), Positives = 260/374 (69%), Gaps = 17/374 (4%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQS-----TFNINEYRQAG 55
M+ TLH RAE KPLE R+ALTPTT KKL+ G+ + VE SP+ F E+ QAG
Sbjct: 1 MSFPTLHARAEAKPLEHRSALTPTTAKKLLDAGYPVLVERSPKDPNYARIFKDEEFEQAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A ++ G++KTAP+DRIIIGLKE+PE D FPL H + FAHCYK Q GW+ VL RF +G
Sbjct: 61 ATLIEEGAYKTAPKDRIIIGLKELPE-DEFPLEHTFVHFAHCYKQQGGWEKVLARFPRGG 119
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
GTLYDLEFL++ GRRVAAFG++AGF GAAL ++ WA++ TH + E LP V
Sbjct: 120 GTLYDLEFLQDTTGRRVAAFGYHAGFVGAALAIKTWAWQLTHPNGEPLPGVETFTDGRGY 179
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE L+ + +D KP+ L++GALGRCGSGA+DLL K+G P+ I KWD+
Sbjct: 180 YNNESELITQLKEDVAAGEKVAGHKPSSLVLGALGRCGSGAVDLLEKIGCPE--IKKWDL 237
Query: 229 KET-SRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHN 287
ET R GP+ EI ++DIF+NCIYLSKPI PF N E L +P R+L V DVS DTTNPHN
Sbjct: 238 PETKERDGPYPEIIESDIFVNCIYLSKPIPPFVNKESLKSPKRKLSVVCDVSCDTTNPHN 297
Query: 288 PIPIYTVATVFNKPTVLVPTTA-GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQ 346
PIPIY + T F+KPTV V GP+LSVISIDHLPS LPRE+SE FS+ LLPSL L
Sbjct: 298 PIPIYDINTTFDKPTVGVDVEGDGPRLSVISIDHLPSALPRESSEAFSNALLPSLMALKD 357
Query: 347 RKTAPVWVRAKKLF 360
R T PVW A+KLF
Sbjct: 358 RATTPVWQGAEKLF 371
>ref|XP_001399884.1| hypothetical protein An02g07500 [Aspergillus niger]
emb|CAK37714.1| unnamed protein product [Aspergillus niger]
Length = 377
Score = 409 bits (1050), Expect = e-112, Method: Composition-based stats.
Identities = 207/377 (54%), Positives = 265/377 (70%), Gaps = 6/377 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F+ ++ + GA +V
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSTQRIFDDEDFAKIGAPLVE 60
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK Q GW+ VL R+ +G GTL
Sbjct: 61 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQGGWEQVLSRWPRGGGTLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP PY N+ AL++ V
Sbjct: 120 DLEFLTDDVGRRVAAFGWSAGYAGSALAVKNWAWQLTHPEGEPLPGEVPYINQDALIESV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
K ++ R P +L+IGALGRCGSGA+ L VGIPD++I++WDI+ET +GGPF E
Sbjct: 180 KKSLEDGKKQSGRSPKILVIGALGRCGSGAVQLAKDVGIPDSDIVRWDIEETKKGGPFRE 239
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + DI +NCIYLS I PF E L +P RRL + DVSADTTNPHNP+P+Y++ T F
Sbjct: 240 IVEDVDILVNCIYLSAQIPPFVTPETLTSPKRRLSVICDVSADTTNPHNPLPVYSITTTF 299
Query: 299 NKPTVLVPTTAGPK---LSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV V G + LSVISIDHLPSLLPRE+SE FS LLPSL L R+ A VW +
Sbjct: 300 DKPTVPVTLAGGNQVAGLSVISIDHLPSLLPRESSEMFSQALLPSLLQLKDRQNARVWKQ 359
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF+ A + S R
Sbjct: 360 AEDLFNEKVATLPESLR 376
>ref|XP_001271170.1| saccharopine dehydrogenase Lys1, putative [Aspergillus clavatus
NRRL 1]
gb|EAW09744.1| saccharopine dehydrogenase Lys1, putative [Aspergillus clavatus
NRRL 1]
Length = 380
Score = 409 bits (1050), Expect = e-112, Method: Composition-based stats.
Identities = 212/381 (55%), Positives = 266/381 (69%), Gaps = 11/381 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTF----NINEYRQAGA 56
M++ + LRAETKP EAR+ALTPTT K L+ G+ + VE S Q F NI Y GA
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYDVTVERSTQRIFDGEDNILSY-LIGA 59
Query: 57 IIVPAGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
+V GSW K AP+D ++GLKE+PE D FPL H HI FAHCYK+Q GW+ VL R+ +G
Sbjct: 60 PLVEEGSWVKDAPKDAYVLGLKELPEDD-FPLEHVHISFAHCYKEQGGWEKVLSRWPRGG 118
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKAL 175
GTL DLEFL +D GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP +PY N+ L
Sbjct: 119 GTLLDLEFLTDDVGRRVAAFGYSAGYAGSALAVKNWAWQLTHPEGEPLPGETPYENQDLL 178
Query: 176 VKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGG 235
+ V + + + P VL+IGALGRCG GA+ L VGIP+++I++WDI+ET +GG
Sbjct: 179 IASVKESLEVGKKQSGKSPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDIEETKKGG 238
Query: 236 PFDEIPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTV 294
PF EI + DIF+NCIYLS I PF N E L+ PNRRL + DVSADTTNPHNPIP+Y++
Sbjct: 239 PFREIVEDVDIFVNCIYLSAKIPPFVNAETLSTPNRRLSVICDVSADTTNPHNPIPVYSI 298
Query: 295 ATVFNKPTVLVPTTA---GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAP 351
T F+KPTV V +A GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A
Sbjct: 299 TTTFDKPTVPVTLSAGAQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDRKNAR 358
Query: 352 VWVRAKKLFDRHCARVKRSSR 372
VW +A+ LF+ A + S R
Sbjct: 359 VWKQAEDLFNEKVATLPESMR 379
>ref|XP_363433.1| hypothetical protein MGG_01359 [Magnaporthe grisea 70-15]
gb|EDK04946.1| hypothetical protein MGG_01359 [Magnaporthe grisea 70-15]
Length = 365
Score = 407 bits (1047), Expect = e-112, Method: Composition-based stats.
Identities = 220/360 (61%), Positives = 264/360 (73%), Gaps = 12/360 (3%)
Query: 6 LHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWK 65
LHLR+ETKPLE R+ALTPTT K LI G+ + VE SP F+ E+ GA +VP GSW+
Sbjct: 5 LHLRSETKPLEHRSALTPTTTKALIEAGYTVNVERSPVRIFDDAEFEAVGATLVPEGSWE 64
Query: 66 TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLE 125
P+D I+IGLKE+ E D FPL H HIQFAHCYK+Q GW VL R+ G G L D+EFLE
Sbjct: 65 QIPKDHIVIGLKELEEKD-FPLKHTHIQFAHCYKNQGGWDKVLRRYHDGEGMLLDIEFLE 123
Query: 126 NDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYKE 185
D GRRVAAFG++AGFAGAAL +++WA++ T+S E LP+V PNE ALV D+ KE
Sbjct: 124 KD-GRRVAAFGYWAGFAGAALALQNWAWQLTNSG-EPLPSVESRPNEAALVGDI----KE 177
Query: 186 ALATGARK----PTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIP 241
ALA G K P V++IGALGRCG GA+D+ K GIPD NILKWD++ET+ GGPF EI
Sbjct: 178 ALAGGKEKAGRLPRVIVIGALGRCGRGAVDMCKKAGIPDENILKWDMEETAPGGPFKEIV 237
Query: 242 QADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKP 301
++DIF+NCIYL+K I PF ME LN P R+L + D SADTTNP NP+P+YTVAT F+KP
Sbjct: 238 ESDIFVNCIYLNKQIPPFVTMESLNTPERKLSVINDCSADTTNPFNPVPVYTVATTFDKP 297
Query: 302 TVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
TV V + GP LSVISIDHLPSLLPREASE FS+DLLP L L K+ PVW A+KLF
Sbjct: 298 TVPVDGLSHGPPLSVISIDHLPSLLPREASESFSNDLLPYLLKLKDWKSDPVWAGAEKLF 357
>ref|XP_660477.1| hypothetical protein AN2873.2 [Aspergillus nidulans FGSC A4]
gb|EAA63444.1| hypothetical protein AN2873.2 [Aspergillus nidulans FGSC A4]
Length = 1026
Score = 406 bits (1044), Expect = e-111, Method: Composition-based stats.
Identities = 205/378 (54%), Positives = 268/378 (70%), Gaps = 6/378 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M + + LRAETKP EAR+ALTPTT K LI G+++ VE S Q F+ +E+ + GA +V
Sbjct: 1 MGSNKIWLRAETKPAEARSALTPTTCKALIDAGYEVTVERSTQRIFDDDEFAKVGAPLVE 60
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK+QAGW+ VL R+ +G G L
Sbjct: 61 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKEQAGWEKVLSRWPRGGGVLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFGF AG+AGAAL V++WA++ TH + E L PY N+ L++ V
Sbjct: 120 DLEFLTDDAGRRVAAFGFSAGYAGAALAVKNWAWQLTHPEGEPLAGEKPYANQDLLIQSV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + + P +L+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 180 KESLQAGQKQSGKSPKILVIGALGRCGKGAVQLAKDVGIPESDIIQWDMEETKKGGPFKE 239
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIF+NCIYLS I F N+E L+ P+RRL + DVSADTTNP+NPIP+Y + T F
Sbjct: 240 IVEDADIFVNCIYLSSKIPHFVNVESLSTPSRRLSVICDVSADTTNPNNPIPVYNITTTF 299
Query: 299 NKPTVLVPT---TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV V T G LSVISIDHLPSLLPRE+SE FS L+PSL L R+ A VW +
Sbjct: 300 DKPTVPVTLPNGTQGTPLSVISIDHLPSLLPRESSEMFSEALMPSLLQLKDRENARVWKQ 359
Query: 356 AKKLFDRHCARVKRSSRL 373
A+ LF++ A + +++ L
Sbjct: 360 AEDLFNQKVATLPQTAEL 377
>ref|XP_001246345.1| hypothetical protein CIMG_00116 [Coccidioides immitis RS]
gb|EAS34762.1| hypothetical protein CIMG_00116 [Coccidioides immitis RS]
Length = 385
Score = 405 bits (1042), Expect = e-111, Method: Composition-based stats.
Identities = 205/372 (55%), Positives = 254/372 (68%), Gaps = 15/372 (4%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQST-----FNINEYRQAG 55
MA TLHLRAE K LE R+ALTP+T + LI G+ I VE SP S F E+ +AG
Sbjct: 1 MAGTTLHLRAEDKILEHRSALTPSTTRALIDAGYNIKVERSPTSALRKRIFPDEEFEKAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +V GSW AP+D II+GLKE+ ET FPLVH+H+ FAHC+K+Q GW+ L R+ +G
Sbjct: 61 AELVAEGSWVNAPKDSIIVGLKELDETKDFPLVHDHVTFAHCFKNQGGWEKALGRWSRGG 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
G LYDLEFL++D GRRVAAFG++AGFAGAAL ++ WA++ H D LP V
Sbjct: 121 GVLYDLEFLQDDSGRRVAAFGYHAGFAGAALSLKTWAWQLEHPDGTPLPGVDEFTGGKGY 180
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE +V + D + RKP VLIIGALGRCG GA+D K G D IL+WD+
Sbjct: 181 YVNEDEMVNQIRADIERGAKIAGRKPRVLIIGALGRCGRGAVDACVKAGCED--ILRWDM 238
Query: 229 KETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNP 288
ET++GGPF EI ++DIFINCIYL+ I F + E L +PNR+L V DVS DTTNP+NP
Sbjct: 239 AETAKGGPFTEIVESDIFINCIYLTSKIPSFVDEESLKSPNRKLSVVCDVSCDTTNPNNP 298
Query: 289 IPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRK 348
IPIY V T F+KPT+ + T P LSVISIDHLPSLLP E+SE FS DLLPS+ + R
Sbjct: 299 IPIYNVNTTFDKPTLQLNYT-NPPLSVISIDHLPSLLPAESSEAFSTDLLPSMLEIKNRT 357
Query: 349 TAPVWVRAKKLF 360
+ PVW RA+KL+
Sbjct: 358 SHPVWQRAEKLY 369
>sp|Q870G1|LYS1_EMENI Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAL23682.1| putative saccharopine dehydrogenase [Emericella nidulans]
Length = 375
Score = 404 bits (1038), Expect = e-111, Method: Composition-based stats.
Identities = 204/376 (54%), Positives = 265/376 (70%), Gaps = 6/376 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M + + LRAETKP EAR+ALTPTT K LI G+++ VE S Q F+ + Q GA +V
Sbjct: 1 MGSNKIWLRAETKPAEARSALTPTTCKALIDAGYEVTVERSTQRIFDGKIFVQVGAPLVE 60
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK+QAGW+ VL R+ +G G L
Sbjct: 61 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKEQAGWEKVLSRWPRGGGVLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFGF AG+AGAAL V++WA++ TH + E L PY N+ L++ V
Sbjct: 120 DLEFLTDDAGRRVAAFGFSAGYAGAALAVKNWAWQLTHPEGEPLAGEKPYANQDLLIQSV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + + P +L+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 180 KESLQAGQKQSGKSPKILVIGALGRCGKGAVQLAKDVGIPESDIIQWDMEETKKGGPFKE 239
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIF+NCIYLS I F N+E L+ P+RRL + DVSADTTNP+NPIP+Y + T F
Sbjct: 240 IVEDADIFVNCIYLSSKIPHFVNVESLSTPSRRLSVICDVSADTTNPNNPIPVYNITTTF 299
Query: 299 NKPTVLVPT---TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV V T G LSVISIDHLPSLLPRE+SE FS L+PSL L R+ A VW +
Sbjct: 300 DKPTVPVTLPNGTQGTPLSVISIDHLPSLLPRESSEMFSEALMPSLLQLKDRENARVWKQ 359
Query: 356 AKKLFDRHCARVKRSS 371
A+ LF++ A + +++
Sbjct: 360 AEDLFNQKVATLPQTA 375
>ref|XP_001220083.1| hypothetical protein CHGG_00862 [Chaetomium globosum CBS 148.51]
gb|EAQ92627.1| hypothetical protein CHGG_00862 [Chaetomium globosum CBS 148.51]
Length = 375
Score = 400 bits (1029), Expect = e-110, Method: Composition-based stats.
Identities = 215/375 (57%), Positives = 261/375 (69%), Gaps = 7/375 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MA LHLR+ETKPLE R+ALTPTT LI G+ + VE SP F+ E+ AGA +VP
Sbjct: 1 MAPTVLHLRSETKPLEHRSALTPTTTAALIKAGYTVNVERSPVRIFDDAEFEAAGATLVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
SW AP++ IIIGLKE+ E + FPL H H+QFAHCYK Q GW+ VL RF +G GTL D
Sbjct: 61 EYSWVDAPKEHIIIGLKELEEKE-FPLKHVHVQFAHCYKQQGGWETVLARFPRGGGTLLD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL ++ GRRVAAFG++AGFAGAAL + W+++ HS E P V YPNE ALV +V
Sbjct: 120 LEFLVDENGRRVAAFGYHAGFAGAALALEVWSWQLNHS--EPFPGVESYPNEDALVSNVK 177
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K + R P V++IGALGRCGSGA++ L K G+P+ NILKWD+ ET+ GGPF EI
Sbjct: 178 KALASGIEKAGRSPRVIVIGALGRCGSGAVEALRKAGVPEENILKWDMAETAGGGPFKEI 237
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSA---DTTNPHNPIPIYTVATV 297
+DIF+NCIYL+K I F N+E L P+R+L V DVSA DTT+P P+PIYTVAT
Sbjct: 238 TDSDIFVNCIYLTKKIPNFVNLESLQVPDRKLSVVCDVSAASQDTTSPFTPVPIYTVATT 297
Query: 298 FNKPTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRA 356
F++PTV V +GP LSVISIDHLPSLLPREASE FS DLLPSL L + PVW RA
Sbjct: 298 FDEPTVAVEGLQSGPALSVISIDHLPSLLPREASEAFSQDLLPSLLALNDWQNTPVWSRA 357
Query: 357 KKLFDRHCARVKRSS 371
KLF A + S+
Sbjct: 358 DKLFKEKVATLPASA 372
>ref|XP_001819876.1| hypothetical protein [Aspergillus oryzae RIB40]
dbj|BAE57874.1| unnamed protein product [Aspergillus oryzae]
Length = 377
Score = 398 bits (1023), Expect = e-109, Method: Composition-based stats.
Identities = 207/375 (55%), Positives = 263/375 (70%), Gaps = 11/375 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQA-----G 55
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F+ +A G
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTAKALMDAGYEVTVERSTQRIFDGRLSIRAPLSRIG 60
Query: 56 AIIVPAGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKG 114
A +V GSW K AP+D ++GLKE+PE D FPL H HI FAHCYK Q GW+ VL R+ +G
Sbjct: 61 APLVEEGSWAKDAPKDAYVLGLKELPEDD-FPLEHVHITFAHCYKQQGGWEKVLRRWPRG 119
Query: 115 HGTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKA 174
GTL DLEFL ++ GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP PY N+
Sbjct: 120 GGTLLDLEFLTDEVGRRVAAFGWSAGYAGSALAVKNWAWQLTHPEGEPLPGEVPYANQDL 179
Query: 175 LVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRG 234
L + V + + R P +L+IGALGRCG+GA+ L VGIP+++I++WDI+ET +G
Sbjct: 180 LTQSVKESLEAGKKQSGRSPKILVIGALGRCGNGAVQLAKDVGIPESDIIRWDIEETKKG 239
Query: 235 GPFDEIPQADIFINCIYL-SKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYT 293
GPF EI ADIF+NCIYL S+ I PF N+E L+ PNRRL + DVSADTTNP+NPIP+Y
Sbjct: 240 GPFQEIIDADIFVNCIYLSSESIPPFVNVESLSTPNRRLSVICDVSADTTNPNNPIPVYD 299
Query: 294 VATVFNKPTV---LVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTA 350
+ T F+KPTV L T GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A
Sbjct: 300 ITTTFDKPTVPVTLPAGTQGPPLSVISIDHLPSLLPRESSEMFSQALLPSLLQLKNRKDA 359
Query: 351 PVWVRAKKLFDRHCA 365
VW +A+ LF + A
Sbjct: 360 RVWTQAEDLFKQKVA 374
>gb|EEH34800.1| saccharopine dehydrogenase [Paracoccidioides brasiliensis Pb01]
Length = 384
Score = 385 bits (990), Expect = e-105, Method: Composition-based stats.
Identities = 202/372 (54%), Positives = 255/372 (68%), Gaps = 15/372 (4%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQST-----FNINEYRQAG 55
M+ VTLHLRAE K LE R+ALTP T + L+ G+ + VE SP S F E+ +AG
Sbjct: 1 MSPVTLHLRAEDKILEHRSALTPATTRALVDAGYIVRVERSPTSALRKRIFPDAEFEEAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +VP GSW AP D II+GLKE+ ET FPL H H+ FAHCYK+Q GW+ L R+ +G+
Sbjct: 61 ATLVPEGSWVDAPLDSIILGLKELDETKDFPLRHAHVTFAHCYKNQGGWEKSLGRWSRGN 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
G LYDLEFL++D GRR+AAFG++AGFAGAAL ++ WA++ H D LP V
Sbjct: 121 GVLYDLEFLQDDNGRRIAAFGYHAGFAGAALALKTWAWQLEHPDGTPLPGVEQFTDGRGY 180
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE ++ + D R+P VLIIGALGRCG GA+D K G D IL+WD+
Sbjct: 181 YLNEAEMIGQIRNDVARGEKIATRRPRVLIIGALGRCGKGAVDACVKAGCED--ILRWDM 238
Query: 229 KETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNP 288
ET++GGPF EI ++DIF+NCIYLS+ IAPF +ME L +P+RRL + DVS DTTNP+NP
Sbjct: 239 AETAKGGPFQEIVESDIFVNCIYLSEKIAPFVDMESLKSPDRRLSVICDVSCDTTNPNNP 298
Query: 289 IPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRK 348
IPIY + T F KPTV +P + P LSVISIDHLPSLLP E+S FS DLLP ++ + R
Sbjct: 299 IPIYNINTTFGKPTVALPLS-NPPLSVISIDHLPSLLPAESSNAFSADLLPYMKEIKHRD 357
Query: 349 TAPVWVRAKKLF 360
+ PVW RA+KLF
Sbjct: 358 SNPVWQRAEKLF 369
>ref|XP_001828899.1| hypothetical protein CC1G_03693 [Coprinopsis cinerea okayama7#130]
gb|EAU92906.1| hypothetical protein CC1G_03693 [Coprinopsis cinerea okayama7#130]
Length = 369
Score = 366 bits (940), Expect = 1e-99, Method: Composition-based stats.
Identities = 211/363 (58%), Positives = 249/363 (68%), Gaps = 11/363 (3%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M+ TL LR E K E RAALTPTT KKLI GF I+VE Q F+ +EY AG +V
Sbjct: 1 MSKPTLWLRCEKKEFERRAALTPTTAKKLIEAGFDIFVEKDEQRIFDDSEYEAAGCKLVE 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
+W +AP+D IIGLKE+P +D PL H HIQFAHCYK Q GW VL RF KG GTLYD
Sbjct: 61 NNTWASAPKDVPIIGLKELPVSDE-PLPHTHIQFAHCYKKQGGWSQVLARFYKGGGTLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL ++ GRRVAAFGF+AGFAGAA G A ++ +DL ++PYPNE A+V DV
Sbjct: 120 LEFLNDENGRRVAAFGFHAGFAGAAAGALAVAARR---QGKDLGLLTPYPNEAAMVDDV- 175
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K++L + L+IGALGRCG GA+DL K+G+ + +ILKWD+ ET++GGPF EI
Sbjct: 176 ---KKSLGGSGKGLKALVIGALGRCGRGAVDLFRKIGLEENDILKWDMAETAKGGPFPEI 232
Query: 241 PQADIFINCIYLSKPIAPFTNMEK--LNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
DIF+NCIYLS I F E +RRL VVDVS DTTNP+NPIPIY + T F
Sbjct: 233 LDVDIFVNCIYLSSQIPSFITKETAIAAGKDRRLSVVVDVSCDTTNPYNPIPIYNINTTF 292
Query: 299 NKPTVLVPTTA-GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAK 357
+KPTV V A P LSVISIDHLP+LLPREASE FS DLLPSL PQR TA VWV A+
Sbjct: 293 DKPTVAVDVGAENPPLSVISIDHLPTLLPREASEQFSGDLLPSLLEFPQRSTARVWVEAE 352
Query: 358 KLF 360
KLF
Sbjct: 353 KLF 355
>ref|XP_570078.1| saccharopine dehydrogenase (NAD+, L-lysine-forming) [Cryptococcus
neoformans var. neoformans JEC21]
ref|XP_776193.1| hypothetical protein CNBD0140 [Cryptococcus neoformans var.
neoformans B-3501A]
gb|EAL21546.1| hypothetical protein CNBD0140 [Cryptococcus neoformans var.
neoformans B-3501A]
gb|AAW42771.1| saccharopine dehydrogenase (NAD+, L-lysine-forming), putative
[Cryptococcus neoformans var. neoformans JEC21]
Length = 395
Score = 361 bits (927), Expect = 4e-98, Method: Composition-based stats.
Identities = 209/357 (58%), Positives = 250/357 (70%), Gaps = 6/357 (1%)
Query: 8 LRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWKTA 67
LR E KP E R+ALTPTT K L+ F +YVE PQ F+ E+ G IVP +W +A
Sbjct: 23 LRCEKKPFEHRSALTPTTAKTLLDSNFDVYVEKDPQRIFDDREFEAVGCKIVPHNTWPSA 82
Query: 68 PRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLEND 127
P D IIGLKE+PE+ T PL H HIQFAHCYK QAGW +VL RF +G GTLYDLEFLE+
Sbjct: 83 PVDVPIIGLKELPES-TDPLPHTHIQFAHCYKQQAGWNDVLRRFAQGKGTLYDLEFLEDP 141
Query: 128 -QGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYKEA 186
RRVAAFGF+AGFAGAA G +A +QT + L + PYPNE +VK+V++ +
Sbjct: 142 VSHRRVAAFGFHAGFAGAAAGALAFAAQQTQNGQGKLGELKPYPNEGEMVKEVSEAL-QG 200
Query: 187 LATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQADIF 246
G + VLIIGALGRCGSGA+DL K G+ + NI+KWD+ ET++GGPF EI DIF
Sbjct: 201 TKEGNKGVKVLIIGALGRCGSGAVDLFRKAGVAEENIIKWDMAETAKGGPFPEILDVDIF 260
Query: 247 INCIYLSKPIAPFTNMEKLNN--PNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPTVL 304
+NCIYLSKPI F E + +RRL VVDVS DTTNPHNPIPIY++ T F PTV
Sbjct: 261 VNCIYLSKPIPKFITSEFIAEAGADRRLSVVVDVSCDTTNPHNPIPIYSINTTFPSPTVE 320
Query: 305 VPTTA-GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
V T G + +VISIDHLP+LLPREASE FS DLLPSL LP+R+TA VWV A+KLF
Sbjct: 321 VDTKGVGKRCTVISIDHLPTLLPREASEQFSTDLLPSLLQLPERQTAEVWVNAEKLF 377
>ref|XP_001544099.1| saccharopine dehydrogenase [Ajellomyces capsulatus NAm1]
gb|EDN03281.1| saccharopine dehydrogenase [Ajellomyces capsulatus NAm1]
Length = 376
Score = 358 bits (920), Expect = 3e-97, Method: Composition-based stats.
Identities = 196/372 (52%), Positives = 250/372 (67%), Gaps = 23/372 (6%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQST-----FNINEYRQAG 55
MA VTLHLR E K LE R+ALTP T + L+ G+ + +E SP S F E+ +AG
Sbjct: 1 MAPVTLHLRTEDKILEHRSALTPQTTRLLVDAGYIVNIERSPTSALRKRIFPDAEFEKAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +VP GSW AP D II+GLKE+ ET FPL H H+ FAHCYK Q GW+ L R+ +G+
Sbjct: 61 ATLVPEGSWVDAPLDHIILGLKELDETKDFPLRHAHVTFAHCYKGQGGWEKALGRWSRGN 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
G LYDLEFL++D GRR+AAFG++AGFAGAAL ++ WA++ H D LP+V
Sbjct: 121 GVLYDLEFLQDDIGRRIAAFGYHAGFAGAALALKTWAWQLQHPDTP-LPSVDHFTDGRGY 179
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NEK +V + +D KP VL+IGALGRCG GA+D K G D +L+WD+
Sbjct: 180 YLNEKEMVDQIREDVIRGEKIAGHKPRVLVIGALGRCGRGAVDACVKAGCED--VLRWDM 237
Query: 229 KETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNP 288
ET++GGPF EI ++DIF+NCIYL++ I PF +ME L +PNR+L V DVS DTTNP+NP
Sbjct: 238 AETAKGGPFQEIVESDIFVNCIYLNEKIPPFVDMESLKSPNRKLSVVCDVSCDTTNPNNP 297
Query: 289 IPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRK 348
I F+KPTV +P + P LSVISIDHLPSLLP E+S+ FS DLLP + + R
Sbjct: 298 I-------TFDKPTVPLPLS-NPPLSVISIDHLPSLLPAESSDAFSTDLLPCMMEIKNRA 349
Query: 349 TAPVWVRAKKLF 360
+ PVW RA+KLF
Sbjct: 350 SHPVWQRAEKLF 361
>ref|XP_001745712.1| predicted protein [Monosiga brevicollis MX1]
gb|EDQ89683.1| predicted protein [Monosiga brevicollis MX1]
Length = 499
Score = 354 bits (908), Expect = 7e-96, Method: Composition-based stats.
Identities = 179/368 (48%), Positives = 240/368 (65%), Gaps = 9/368 (2%)
Query: 5 TLHL--RAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQST----FNINEYRQAGAII 58
T+HL R+E K E R ALTP K+L+ +G+ I VE SP+++ + ++Y G +
Sbjct: 130 TMHLWLRSEVKANEHRTALTPEACKELLGEGYTITVERSPEASTKRIYEDSDYEAVGCQL 189
Query: 59 VPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTL 118
+ SW +AP+D II+GLKE+PE D PL H H+ F HCYK+Q GW+++L RF G+G+L
Sbjct: 190 AESQSWPSAPKDAIIVGLKELPE-DGSPLEHTHLYFGHCYKNQGGWKDLLKRFHAGNGSL 248
Query: 119 YDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKD 178
D+EFL NDQGRRVAAFG+ AGFAG+ + W ++ D + A+S YPNE L+K
Sbjct: 249 LDMEFLTNDQGRRVAAFGYMAGFAGSFSALDVWCHRKLEGD-KPYGALSAYPNEDELLKY 307
Query: 179 VTKDYKEALATG-ARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPF 237
+ A A R P VL+IGALGRCG+GA D + GIP+AN+L+WD+ ET GGPF
Sbjct: 308 SRARIEAAAAKNDGRLPRVLVIGALGRCGNGACDFATRAGIPEANVLRWDMAETKVGGPF 367
Query: 238 DEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATV 297
+E+ DIF+NCIYLS+PI PF L +R L V DVS DT+NPHNPIP +T
Sbjct: 368 NELLDVDIFVNCIYLSQPIPPFITEAMLEKEDRALSVVCDVSCDTSNPHNPIPFANKSTT 427
Query: 298 FNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAK 357
F++PT V G + VI+IDHLP+LLP+E+S+ + HDLLPS+ L + PVW RA
Sbjct: 428 FDEPTYQVKPKVGGPVDVITIDHLPTLLPKESSDRYCHDLLPSIRELKNMDSNPVWQRAI 487
Query: 358 KLFDRHCA 365
KLF+ A
Sbjct: 488 KLFEEKKA 495
>emb|CAX65448.1| putative saccharopine dehydrogenase (NAD+,L-lysine-forming)
[Gibberella fujikuroi]
Length = 390
Score = 353 bits (906), Expect = 1e-95, Method: Composition-based stats.
Identities = 194/381 (50%), Positives = 240/381 (62%), Gaps = 19/381 (4%)
Query: 8 LRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAGAIIVPAG 62
LRAE KPLE R+ +P +K L+ G+ I VE S + F +EY AGA +V G
Sbjct: 9 LRAEEKPLEHRS-FSPAIIKTLVDAGYPISVERSSTDPKFKRIFEDSEYEAAGARLVDTG 67
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
W A II+GLKE+P D FPL ++HI FAHCYK+Q GW+ VL R+ +G LYDLE
Sbjct: 68 VWPNAEPGTIILGLKELPSED-FPLKNDHITFAHCYKNQGGWEQVLGRWARGGSRLYDLE 126
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP-------YPNEKAL 175
FL ++QGRRV+AFG++AGFAGAALG++ A Q LP+V Y NE L
Sbjct: 127 FLVDEQGRRVSAFGYHAGFAGAALGIKTLA-HQLQGSSSKLPSVETFTDGRGYYLNEDEL 185
Query: 176 VKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETS-RG 234
V + +D +A RKPT L++GALGRCG GA+DL K G+PD NI +WD+ ET R
Sbjct: 186 VNQIREDLAKAEKALGRKPTALVLGALGRCGKGAVDLFLKAGMPDDNITRWDLNETKDRD 245
Query: 235 GPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTV 294
GP++EI +AD+F+N IYLSKPI PF N E L R L V+DVS DTTNPHNPIPIY++
Sbjct: 246 GPYEEIAKADVFLNAIYLSKPIPPFINQELLAKQGRNLAVVIDVSCDTTNPHNPIPIYSI 305
Query: 295 ATVFNKPTVLVPTTAGPK---LSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAP 351
T F PTV V LSVISIDHLPS+LPREASE FS L SL L R+T+
Sbjct: 306 NTTFEDPTVPVEIKDDQNNLPLSVISIDHLPSMLPREASEAFSEGLKESLLTLKDRETSR 365
Query: 352 VWVRAKKLFDRHCARVKRSSR 372
VW A+KLF A + R
Sbjct: 366 VWTDAEKLFHEKVALLPEELR 386
>ref|XP_001873276.1| predicted protein [Laccaria bicolor S238N-H82]
gb|EDR15068.1| predicted protein [Laccaria bicolor S238N-H82]
Length = 367
Score = 351 bits (900), Expect = 6e-95, Method: Composition-based stats.
Identities = 193/362 (53%), Positives = 234/362 (64%), Gaps = 10/362 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M+ L LR E K E RAALTPTT KLIA GF I+VE Q F+ +EY G +V
Sbjct: 1 MSKPILWLRCEKKEFERRAALTPTTSSKLIAAGFDIFVERDEQRIFDDSEYEAVGCTLVD 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
SW TA IIGLKE+PE+ T PL H HIQFAHCYK QAGW VL RF +G GTLYD
Sbjct: 61 NNSWPTARTSTPIIGLKELPES-TDPLPHTHIQFAHCYKQQAGWSKVLSRFHRGGGTLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL++ GRRVAA + AG A +L ++PY NE+A+V +V
Sbjct: 120 LEFLQDANGRRVAA---FGFHAGFAGAAAGALALAAQRGGNELGLLTPYANEEAMVNNV- 175
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KE L + L+IGALGRCG GA+DL K+G+ + +ILKWD++ET++GGPF +I
Sbjct: 176 ---KELLGGSGKGVRALVIGALGRCGRGAVDLFRKIGLDEDDILKWDLEETAKGGPFSKI 232
Query: 241 PQADIFINCIYLSKPIAPFTNMEKL--NNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
DIF+NCIYL+ I F E++ +RRL VVDVS DTTNP NPIPIY + T F
Sbjct: 233 LDVDIFVNCIYLTSQIPSFVTREQVIAAGKDRRLSVVVDVSCDTTNPFNPIPIYNINTTF 292
Query: 299 NKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKK 358
+KPTV V P LSVISIDHLP+LLPREASE FS DLLPSL P+R+T+ VW AK+
Sbjct: 293 DKPTVPVDVGGLPALSVISIDHLPTLLPREASEQFSSDLLPSLLEFPERETSRVWADAKR 352
Query: 359 LF 360
LF
Sbjct: 353 LF 354
>gb|EEH50065.1| saccharopine dehydrogenase [Paracoccidioides brasiliensis Pb18]
Length = 377
Score = 343 bits (880), Expect = 1e-92, Method: Composition-based stats.
Identities = 188/372 (50%), Positives = 240/372 (64%), Gaps = 22/372 (5%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQST-----FNINEYRQAG 55
M+ VTLHLRAE K LE R+ALTP T + L+ G+ + VE SP S F E+ +AG
Sbjct: 1 MSPVTLHLRAEDKILEHRSALTPATTRALVDAGYIVKVERSPTSALRKRIFPDAEFEEAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +VP GSW AP D II+GLKE+ ET FPL H H+ FAHCYK+Q GW+ L R+ +G+
Sbjct: 61 ATLVPEGSWVDAPLDSIILGLKELDETKDFPLRHAHVTFAHCYKNQGGWEKSLGRWSRGN 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
G LYDLEFL+ G++AGFAGAAL ++ W ++ H D LP V
Sbjct: 121 GVLYDLEFLQVSLIIIGQFGGYHAGFAGAALALKTWVWQLEHPDGTPLPGVEQFTDGRGY 180
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE ++ + D R+P +L+IGALGRCG GA+D K G D IL+WD+
Sbjct: 181 YLNEAEMISQIRNDVARGEKIATRRPRILVIGALGRCGKGAVDACVKAGCED--ILRWDM 238
Query: 229 KETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNP 288
ET++GGPF EI ++D+F+NCIYLS+ IAPF +ME L +PNRRL + DVS DTTNP+NP
Sbjct: 239 AETAKGGPFQEIVESDVFVNCIYLSEKIAPFIDMESLKSPNRRLSVICDVSCDTTNPNNP 298
Query: 289 IPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRK 348
I F KPTV +P + P LSVISIDHLPSLLP E+S FS DLLP ++ + R
Sbjct: 299 I-------TFGKPTVALPLS-NPPLSVISIDHLPSLLPAESSNAFSADLLPYMKEIRHRD 350
Query: 349 TAPVWVRAKKLF 360
+ PVW RA+KLF
Sbjct: 351 SNPVWQRAEKLF 362
>ref|XP_391101.1| hypothetical protein FG10925.1 [Gibberella zeae PH-1]
Length = 383
Score = 342 bits (878), Expect = 2e-92, Method: Composition-based stats.
Identities = 192/381 (50%), Positives = 242/381 (63%), Gaps = 26/381 (6%)
Query: 8 LRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAGAIIVPAG 62
LRAE KPLE R+ +P+ +K L+ G+ + VE S + F +EY AGA +V G
Sbjct: 9 LRAEEKPLEHRS-FSPSIIKTLVDAGYPVSVERSSTDPKFKRIFEDSEYEAAGARLVNEG 67
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
+W A +I+GLKE+PE D FPL ++HI +Q GW+ VL RF +G LYDLE
Sbjct: 68 TWPNAEAGTLILGLKEIPEED-FPLKNDHI-------NQGGWEKVLGRFPQGSSVLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP-------YPNEKAL 175
FL ++QGRRV+AFGF+AGFAGAALG++ A Q LP+V Y NE+ L
Sbjct: 120 FLVDEQGRRVSAFGFHAGFAGAALGIKTLA-HQLQDPSSKLPSVETFTDGRGYYLNEEEL 178
Query: 176 VKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETS-RG 234
V + +D +A + RKPT L++GALGRCG GA+DL K G+PD NI +WD+ ET R
Sbjct: 179 VNQIREDLAKAEKSLGRKPTALVLGALGRCGKGAVDLFLKAGMPDENITRWDLNETKDRD 238
Query: 235 GPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTV 294
GP++EI QAD+F+N IYLSKPI PF N E L R L V+DVS DTTNPHNPIPIY++
Sbjct: 239 GPYEEIAQADVFLNAIYLSKPIPPFINEELLAKSGRNLAVVIDVSCDTTNPHNPIPIYSI 298
Query: 295 ATVFNKPTVLVPTTAGPK---LSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAP 351
T F +PTV V LSVISIDHLPS+LPREASE FS L SL L RKT+
Sbjct: 299 NTTFEEPTVPVEIKNDQNSLPLSVISIDHLPSMLPREASEAFSEGLKESLLTLKDRKTSR 358
Query: 352 VWVRAKKLFDRHCARVKRSSR 372
VW A+KLF+ A + S R
Sbjct: 359 VWADAEKLFNEKVALLPESLR 379
>ref|XP_760415.1| hypothetical protein UM04268.1 [Ustilago maydis 521]
gb|EAK85317.1| hypothetical protein UM04268.1 [Ustilago maydis 521]
Length = 390
Score = 337 bits (863), Expect = 1e-90, Method: Composition-based stats.
Identities = 198/386 (51%), Positives = 249/386 (64%), Gaps = 24/386 (6%)
Query: 6 LHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWK 65
L+LR E KP E RAALTPTT K LI GF I VE PQ F+ EY + G + P ++
Sbjct: 8 LYLRCEMKPAEHRAALTPTTAKALIDAGFDITVESDPQRIFDDKEYTEVGCKLAPHNTFH 67
Query: 66 TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLE 125
+ P D IIGLKE+ E L H HIQFAHCYK QAGW +VL RF +G G LYDLEFLE
Sbjct: 68 SLPADIPIIGLKELEEPGP-DLPHTHIQFAHCYKKQAGWADVLGRFKRGGGKLYDLEFLE 126
Query: 126 NDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALV---KDVTKD 182
+ GRRVAAFG++AGFAGAALG+ +Q +D+ L A YPNE+AL+ K +
Sbjct: 127 DKNGRRVAAFGWHAGFAGAALGLLA-LAEQVQGEDQRLGAQKAYPNEQALIAHAKQQIEF 185
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETS-RGGPFDEIP 241
K++ + G K L++GALGRCG GAID K G+ +I++WDI+ETS + GP+ E+
Sbjct: 186 IKKSRSDG--KVKALVVGALGRCGRGAIDFFEKAGVASEDIVRWDIQETSAKHGPYQELL 243
Query: 242 QADIFINCIYLSKPIAPFTNMEKLN--NPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
DIF+NCIYL+ I PF + + P+RRL VVDVS DTTNP+NP+PIY + T F+
Sbjct: 244 DVDIFVNCIYLTSKIPPFLDQPTIQAAGPSRRLGVVVDVSCDTTNPNNPLPIYDINTTFD 303
Query: 300 KPTVLVPTTAG-PKLSVISIDHLPSLLPREASEFFSHDLLPSLELLP------------- 345
KPTV V T G P L+VISIDHLP+LLPRE+SE FS+DLLPSL LP
Sbjct: 304 KPTVDVNTGKGNPSLTVISIDHLPTLLPRESSEGFSNDLLPSLLQLPYVLGKDTTKLDTL 363
Query: 346 QRKTAPVWVRAKKLFDRHCARVKRSS 371
VW RA+KLF +H A ++ +
Sbjct: 364 DEGKGAVWQRAEKLFHKHLAEAEQHT 389
>ref|XP_001732779.1| hypothetical protein MGL_0554 [Malassezia globosa CBS 7966]
gb|EDP45565.1| hypothetical protein MGL_0554 [Malassezia globosa CBS 7966]
Length = 386
Score = 306 bits (784), Expect = 2e-81, Method: Composition-based stats.
Identities = 195/387 (50%), Positives = 239/387 (61%), Gaps = 25/387 (6%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
A L LR ETK E R+ALTPTT KKLI GF I VE PQ F+ +E+ + G +
Sbjct: 4 AQPLWLRCETKTAEHRSALTPTTAKKLIDAGFDITVERDPQRIFDDSEFEKVGCHLADYH 63
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
+W +APR I+GLKE+ +T L H HIQFAHCYK Q GW +VL RF +G G LYDLE
Sbjct: 64 TWPSAPRTTPILGLKEL-DTPGPDLEHTHIQFAHCYKQQDGWVDVLARFKRGGGKLYDLE 122
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
FLE+ GRRVAAFG++AGFAGAALG+ L + YPNE +L++
Sbjct: 123 FLEDANGRRVAAFGWHAGFAGAALGLLA---LAEQVQGRQLGKQTMYPNESSLLEQTRAA 179
Query: 183 YKEALATGAR-KPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETS-RGGPFDEI 240
+ A + + T L+IGALGRCG GAID L K G I++WDI+ETS + GP+ EI
Sbjct: 180 VETIRAHRSDGRVTSLVIGALGRCGRGAIDCLEKSGFKADEIVRWDIQETSAKSGPYQEI 239
Query: 241 PQADIFINCIYLSKPIAPFTNMEKL--NNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
+D+FINCIYLSK I PF N + L RRL +VDVS DTTNP+NPIP+Y+V T F
Sbjct: 240 ANSDLFINCIYLSKKIPPFINRDLLAAAGSQRRLGMIVDVSCDTTNPNNPIPVYSVNTTF 299
Query: 299 NKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSL------------ELLPQ 346
KPTV V L VISIDHLP+LLPRE+SE FSHDLLPSL + L Q
Sbjct: 300 EKPTVRVDGV--DNLEVISIDHLPTLLPRESSEAFSHDLLPSLLQLPLIQGDDGPDALAQ 357
Query: 347 RKT---APVWVRAKKLFDRHCARVKRS 370
VW RA+KLF H A +++
Sbjct: 358 DHAEGEGAVWARAEKLFRHHLAEAEKN 384
>ref|XP_001634023.1| predicted protein [Nematostella vectensis]
gb|EDO41960.1| predicted protein [Nematostella vectensis]
Length = 374
Score = 291 bits (746), Expect = 4e-77, Method: Composition-based stats.
Identities = 161/366 (43%), Positives = 222/366 (60%), Gaps = 11/366 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAI--IVP 60
A L LRAE KPLE RA LTP K+L+ GFK+ VE S Q F EY + + P
Sbjct: 2 AAHLWLRAECKPLERRAHLTPEKCKELVDAGFKVTVESSDQRIFKNEEYASIAGVEVLAP 61
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
+W K AP+D II+GLK +P DT P+ H+ FAH YKDQ G + V+ RF +G G +
Sbjct: 62 GITWEKAAPKDAIILGLKNLPYDDTSPISQHHVFFAHAYKDQPGAKEVIGRFTRGGGAIL 121
Query: 120 DLEFLENDQGRR-VAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKD 178
D+E++ N++G+R VA F AG G ALG+ W +Q E +P+VSPY +E LV+
Sbjct: 122 DIEYMLNEEGKREVAEFSPIAGQVGMALGIAGWCHQQL---GERMPSVSPYDSEALLVQH 178
Query: 179 VTKDYKE-ALATGARK--PTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGG 235
V K A G + PT++++GALGRCG G++D+ K+GIP ++I +WD++ET GG
Sbjct: 179 VQSLLKRLAKKKGVAEVYPTIIVLGALGRCGKGSLDMAKKIGIPKSHIAEWDLEETKAGG 238
Query: 236 PFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVA 295
PF EI DIF+N I+L I PF + L+ +R+L VVDVS D NP+NP+P A
Sbjct: 239 PFKEILNYDIFVNDIFLLSKIPPFLTKDMLDTDDRKLTMVVDVSCDIGNPNNPVPFIENA 298
Query: 296 TVFNKPTVLVPTTAGPK-LSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWV 354
T KP ++P + K L +++ID LPS+LPREAS F++ + P L + + A W
Sbjct: 299 TTPTKPVDVLPLSKCSKPLELMAIDFLPSMLPREASLRFANKMTPCLMKIAKMDEAICWS 358
Query: 355 RAKKLF 360
AKK F
Sbjct: 359 SAKKAF 364
>ref|YP_612102.1| alanine dehydrogenase/PNT-like [Silicibacter sp. TM1040]
gb|ABF62840.1| saccharopine dehydrogenase (NAD+, L-lysine-forming) [Silicibacter
sp. TM1040]
Length = 350
Score = 273 bits (698), Expect = 2e-71, Method: Composition-based stats.
Identities = 156/360 (43%), Positives = 216/360 (60%), Gaps = 14/360 (3%)
Query: 6 LHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWK 65
L +RAE + E R LTP K L+ G ++ VE+S + Y AG I P +W
Sbjct: 4 LWVRAEQRLNEDRVGLTPAGAKALLEAGIRVTVEESSSRAIPLQGYIDAGCEIAPENAWP 63
Query: 66 TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLE 125
APRD II GLKE+P+ T PL H HI F H +K Q + +L RF +G GTLYDLE+L
Sbjct: 64 DAPRDAIIFGLKELPDDGT-PLPHRHIMFGHAFKGQHSGKELLRRFREGGGTLYDLEYLV 122
Query: 126 NDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYKE 185
+ GRRVAAFG++AG+AGAA+ ++ WA +Q E V Y N+ AL+ D+ +E
Sbjct: 123 DPSGRRVAAFGYWAGYAGAAVTLKAWAAQQR---GETCGPVGVYKNKDALLADLG---RE 176
Query: 186 ALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQADI 245
ATGA +P ++IGALGR G+GA DL +G+ + KWD+ ET+ GGPF EI D+
Sbjct: 177 LDATGADRPKAIVIGALGRVGTGAADLCEAMGVA---VTKWDMNETASGGPFPEILDHDL 233
Query: 246 FINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPTVLV 305
F+NCI+ ++P P ++ R L + DV+ D + +NP+P+Y+ AT ++ P V V
Sbjct: 234 FLNCIF-ARPGTPVFVPKEALTAARNLTAIGDVACDPDSDYNPVPVYSRATTWDAPVVRV 292
Query: 306 PTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDRHCA 365
P L V++ID+LPS+LP E+SE ++ LL SL L A VW RAK +FD H A
Sbjct: 293 AND--PVLDVMAIDNLPSMLPAESSEDYADQLLASLLTLSDLD-AGVWGRAKAVFDEHVA 349
>ref|ZP_01901689.1| saccharopine dehydrogenase, putative [Roseobacter sp. AzwK-3b]
gb|EDM73387.1| saccharopine dehydrogenase, putative [Roseobacter sp. AzwK-3b]
Length = 353
Score = 273 bits (697), Expect = 2e-71, Method: Composition-based stats.
Identities = 162/364 (44%), Positives = 217/364 (59%), Gaps = 16/364 (4%)
Query: 6 LHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWK 65
L LRAE + E R LTP LIA+G + VEDS I YR AG I P +W
Sbjct: 4 LWLRAEQRANEDRTGLTPEGAAALIARGLTVTVEDSRTRILPIEAYRAAGCAIAPENAWP 63
Query: 66 TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLE 125
APRD II GLKE+P+ T PL H HI F H +K Q + +L RF G GTLYDLE+L
Sbjct: 64 DAPRDAIIFGLKELPDDGT-PLPHRHIMFGHAFKGQHAGRRLLERFKAGGGTLYDLEYLV 122
Query: 126 NDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYKE 185
+ +GRRVAAFG++AG+AGAA+ + WA ++ P VS + ++ AL+ D+
Sbjct: 123 DPEGRRVAAFGYWAGYAGAAISLMAWAAQRQGG---LCPPVSAFADKDALLADLGARLD- 178
Query: 186 ALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQADI 245
ATG ++P+ ++IGALGR G+GA DL +GI +WD+ ET+ GGPF EI DI
Sbjct: 179 --ATGTKRPSAIVIGALGRVGTGAADLCTAMGITPT---RWDMAETAHGGPFPEILAHDI 233
Query: 246 FINCIYLSKPIAP-FTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPTVL 304
F+NCI+ ++P P F E L +R L + DV+ D + +NP+P+Y AT ++ P
Sbjct: 234 FLNCIF-ARPGTPVFVPREALTQ-DRHLTVIGDVACDPDSDYNPVPVYASATTWDAPVTR 291
Query: 305 VPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDRHC 364
V T P L V++ID+LPSLLP E+S ++ LLPSL L A VW RAK FD+H
Sbjct: 292 VHDT--PPLDVMAIDNLPSLLPLESSLDYAAQLLPSLLTLDALD-AGVWGRAKATFDQHM 348
Query: 365 ARVK 368
V+
Sbjct: 349 KEVR 352
>ref|YP_132774.1| hypothetical saccharopine dehydrogenase [Photobacterium profundum
SS9]
emb|CAG22974.1| hypothetical saccharopine dehydrogenase [Photobacterium profundum
SS9]
Length = 353
Score = 272 bits (695), Expect = 3e-71, Method: Composition-based stats.
Identities = 157/355 (44%), Positives = 204/355 (57%), Gaps = 15/355 (4%)
Query: 8 LRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWKTA 67
LR E K E RAALTP LI G + VE S F EY AG +V SW TA
Sbjct: 7 LRDEVKQGERRAALTPAGASALILTGAVVMVEKSSTRIFADAEYLAAGCELVEGHSWVTA 66
Query: 68 PRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLEND 127
P++ I+GLKE+PE D FPL H+HI FAH YK Q VL RF +G G + DLEFL++
Sbjct: 67 PKNAYILGLKELPEDD-FPLQHKHIYFAHAYKGQDEAPQVLARFDQGKGEILDLEFLQDI 125
Query: 128 QGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYKEAL 187
GRRV AFG++AG+ GAA+G + + + D PAV+ YPN + ++ K+ +
Sbjct: 126 SGRRVCAFGYWAGYVGAAIGFAGYCHRL--NSDSTFPAVNSYPNRDVYLAEL----KQLM 179
Query: 188 ATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQADIFI 247
+KPT L+IGA GR G GA+DL +GI ++WDI ET GGPF +I DI +
Sbjct: 180 TQLPQKPTALVIGAYGRSGRGAVDLFADIGI---EAVQWDINETKAGGPFTDINNFDILV 236
Query: 248 NCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPTVLVPT 307
NC YL+ APF E L + RL V DVS D NP NPI IYT T +P ++
Sbjct: 237 NCAYLAPGTAPFITPESLGT-SPRLSMVSDVSCDPNNPDNPIRIYTACTKLTQP-IVQSQ 294
Query: 308 TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAP-VWVRAKKLFD 361
AG + V ++DHLP++LP+E+SE F+ LLP L L VW+RA F+
Sbjct: 295 IAG--IEVQAVDHLPTVLPKESSEDFAEQLLPHLLTLSDNSDPDGVWLRANGFFN 347
>ref|ZP_01219314.1| hypothetical saccharopine dehydrogenase [Photobacterium profundum
3TCK]
gb|EAS44162.1| hypothetical saccharopine dehydrogenase [Photobacterium profundum
3TCK]
Length = 353
Score = 271 bits (693), Expect = 6e-71, Method: Composition-based stats.
Identities = 154/355 (43%), Positives = 203/355 (57%), Gaps = 15/355 (4%)
Query: 8 LRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWKTA 67
LR E K E RAALTP LI G + VE S F EY AG +V SW TA
Sbjct: 7 LRDEVKQGERRAALTPAGASALIQTGAVVMVEKSSTRIFADAEYLAAGCELVEGHSWVTA 66
Query: 68 PRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLEND 127
P++ I+GLKE+PE D FPL H+HI FAH +K Q VL RF +G+G + DLEFL++
Sbjct: 67 PKNAYILGLKELPEDD-FPLQHKHIYFAHAFKGQDEAPQVLARFDQGNGEILDLEFLQDI 125
Query: 128 QGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYKEAL 187
GRRV AFG++AG+ GAA+G + + + D P+V+ YPN + ++ K+ +
Sbjct: 126 SGRRVCAFGYWAGYVGAAIGFAGYCHRL--NSDSTFPSVNSYPNRDVYLAEL----KQLM 179
Query: 188 ATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQADIFI 247
+KPT L+IGA GR G GA+DL +GI ++WDI ET GGPF +I DI +
Sbjct: 180 TQLPQKPTALVIGAYGRSGRGAVDLFADIGI---ETVQWDINETKAGGPFTDINNFDILV 236
Query: 248 NCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPTVLVPT 307
NC YL+ APF E L + + RL V DVS D NP NPI IYT T +P V
Sbjct: 237 NCAYLAPGTAPFITPESLGS-SPRLSMVSDVSCDPNNPDNPIRIYTACTKLTQPIVQSQI 295
Query: 308 TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAP-VWVRAKKLFD 361
+ V ++DHLP++LP+E+SE F+ LLP L L VW+RA F+
Sbjct: 296 VG---IEVQAVDHLPTVLPKESSEDFAEQLLPHLLTLSDNSDPDGVWLRANGFFN 347
>ref|ZP_00630414.1| Alanine dehydrogenase/PNT, C-terminal:Alanine dehydrogenase/PNT,
N-terminal [Paracoccus denitrificans PD1222]
ref|YP_916489.1| alanine dehydrogenase/PNT domain protein [Paracoccus denitrificans
PD1222]
gb|ABL70793.1| saccharopine dehydrogenase (NAD+, L-lysine-forming) [Paracoccus
denitrificans PD1222]
Length = 351
Score = 270 bits (689), Expect = 2e-70, Method: Composition-based stats.
Identities = 156/360 (43%), Positives = 219/360 (60%), Gaps = 14/360 (3%)
Query: 4 VTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGS 63
V L +R E++ E R +TP V++LIA+GF + VE+SP I +Y AGA I P G+
Sbjct: 2 VHLWVRTESRANERRVGITPAGVRELIAQGFHVTVEESPHRILPIADYAAAGAEIAPEGA 61
Query: 64 WKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEF 123
W AP + +I GLKE+PE T PL H HI F H YK Q +L RF +G GTLYDLE+
Sbjct: 62 WPGAPAEAVIFGLKELPEDGT-PLSHRHIMFGHAYKGQPAGLALLRRFREGGGTLYDLEY 120
Query: 124 LENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDY 183
L + GRR+AAFG++AGFAGAA+ ++ WA T V+ +P+++A+ ++
Sbjct: 121 LTDSDGRRLAAFGYWAGFAGAAVTLKAWA---TQRQGGICAPVAGWPSQEAMQDELR--- 174
Query: 184 KEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQA 243
E ATGA +P ++IGALGR G GA DLL +G+ + KWD+ ET+ GGPF EI
Sbjct: 175 AELDATGAPRPHAIVIGALGRVGGGASDLLAAMGV---RVTKWDMAETASGGPFPEILAH 231
Query: 244 DIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPTV 303
++FINCI L+ P P + +P RRLR + DV+ D ++ NP+ +Y AT + +P +
Sbjct: 232 ELFINCI-LAGPRTPVFVPPEAVDPGRRLRVIGDVACDPSSDFNPVKVYDRATNWAEPVI 290
Query: 304 LVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDRH 363
V P L V++ID+LPSLLPRE++ ++ LLP L+ L R W RA+ F H
Sbjct: 291 RVADH--PPLDVMAIDNLPSLLPRESALDYAGQLLPVLKGL-DRIDEGAWGRARATFQDH 347
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
pdb|2QRJ|A Chain A, Crystal Structure Of Sulfate-Bound Sacc... 625 e-177
ref|NP_012300.1| Saccharopine dehydrogenase (NAD+, L-lysine... 625 e-177
emb|CAA54551.1| saccharopine dehydrogenase (NAD+, L-lysine ... 624 e-177
pdb|2Q99|A Chain A, Crystal Structure Of Saccharopine Dehyd... 622 e-176
ref|XP_446267.1| unnamed protein product [Candida glabrata]... 605 e-171
ref|XP_001387327.1| Saccharopine dehydrogenase [NAD+, L-lys... 602 e-170
ref|XP_454310.1| unnamed protein product [Kluyveromyces lac... 598 e-169
ref|XP_001523078.1| saccharopine dehydrogenase [Lodderomyce... 597 e-169
ref|XP_457987.1| hypothetical protein DEHA0C07832g [Debaryo... 596 e-168
ref|XP_001643683.1| hypothetical protein Kpol_1057p13 [Vand... 587 e-166
sp|P43065|LYS1_CANAL Saccharopine dehydrogenase [NAD+, L-ly... 580 e-164
ref|XP_001213891.1| hypothetical protein ATEG_04713 [Asperg... 571 e-161
ref|XP_660477.1| hypothetical protein AN2873.2 [Aspergillus... 570 e-161
ref|XP_001482345.1| hypothetical protein PGUG_05365 [Pichia... 568 e-160
ref|XP_500931.1| YlLYS5 [Yarrowia lipolytica] >gi|729965|sp... 566 e-159
ref|NP_983569.1| ACR167Cp [Ashbya gossypii ATCC 10895] >gi|... 564 e-159
ref|XP_001399884.1| hypothetical protein An02g07500 [Asperg... 563 e-159
ref|XP_754450.1| saccharopine dehydrogenase Lys1 [Aspergill... 561 e-158
ref|XP_001263295.1| saccharopine dehydrogenase Lys1, putati... 561 e-158
ref|XP_001246345.1| hypothetical protein CIMG_00116 [Coccid... 557 e-157
sp|Q870G1|LYS1_EMENI Saccharopine dehydrogenase [NAD+, L-ly... 556 e-157
ref|XP_001271170.1| saccharopine dehydrogenase Lys1, putati... 556 e-156
ref|NP_592972.1| saccharopine dehydrogenase [NAD+, L-lysine... 552 e-155
gb|EDU47954.1| saccharopine dehydrogenase [Pyrenophora trit... 547 e-154
ref|XP_001803532.1| hypothetical protein SNOG_13323 [Phaeos... 546 e-154
ref|XP_001593244.1| saccharopine dehydrogenase [Sclerotinia... 546 e-154
ref|XP_001819876.1| hypothetical protein [Aspergillus oryza... 545 e-153
ref|XP_001559795.1| saccharopine dehydrogenase [Botryotinia... 545 e-153
ref|XP_964977.1| saccharopine dehydrogenase [Neurospora cra... 544 e-153
ref|XP_001908761.1| unnamed protein product [Podospora anse... 541 e-152
ref|XP_001220083.1| hypothetical protein CHGG_00862 [Chaeto... 533 e-150
gb|EEH34800.1| saccharopine dehydrogenase [Paracoccidioides... 533 e-150
ref|XP_363433.1| hypothetical protein MGG_01359 [Magnaporth... 528 e-148
ref|XP_001745712.1| predicted protein [Monosiga brevicollis... 509 e-142
emb|CAX65448.1| putative saccharopine dehydrogenase (NAD+,L... 505 e-141
ref|XP_001544099.1| saccharopine dehydrogenase [Ajellomyces... 505 e-141
ref|YP_612102.1| alanine dehydrogenase/PNT-like [Silicibact... 503 e-141
ref|ZP_01753990.1| saccharopine dehydrogenase, putative [Ro... 503 e-140
ref|XP_391101.1| hypothetical protein FG10925.1 [Gibberella... 492 e-137
ref|ZP_01034544.1| saccharopine dehydrogenase, putative [Ro... 492 e-137
ref|ZP_01901689.1| saccharopine dehydrogenase, putative [Ro... 490 e-137
ref|ZP_01057918.1| saccharopine dehydrogenase, putative [Ro... 489 e-136
ref|YP_168503.1| saccharopine dehydrogenase, putative [Sili... 484 e-135
gb|EEH50065.1| saccharopine dehydrogenase [Paracoccidioides... 484 e-135
ref|XP_001828899.1| hypothetical protein CC1G_03693 [Coprin... 482 e-134
ref|ZP_01002428.1| saccharopine dehydrogenase (NAD+, L-lysi... 480 e-134
ref|ZP_01881158.1| saccharopine dehydrogenase, putative [Ro... 479 e-133
ref|YP_001044623.1| alanine dehydrogenase/PNT domain protei... 478 e-133
ref|ZP_02150991.1| saccharopine dehydrogenase, putative [Ph... 478 e-133
ref|ZP_01751929.1| saccharopine dehydrogenase, putative [Ro... 478 e-133
ref|ZP_02146801.1| saccharopine dehydrogenase, putative [Ph... 477 e-133
ref|YP_354173.1| saccharopine dehydrogenase (NAD+, L-lysine... 476 e-132
ref|XP_001873276.1| predicted protein [Laccaria bicolor S23... 475 e-132
ref|YP_681080.1| saccharopine dehydrogenase, putative [Rose... 472 e-131
ref|ZP_01442866.1| saccharopine dehydrogenase, putative [Ro... 472 e-131
ref|ZP_00630414.1| Alanine dehydrogenase/PNT, C-terminal:Al... 470 e-131
ref|ZP_02152850.1| saccharopine dehydrogenase, putative [Oc... 469 e-130
ref|XP_570078.1| saccharopine dehydrogenase (NAD+, L-lysine... 469 e-130
ref|ZP_02143453.1| saccharopine dehydrogenase, putative [Ro... 468 e-130
ref|ZP_01740684.1| saccharopine dehydrogenase, putative [Rh... 466 e-129
ref|YP_001169133.1| Saccharopine dehydrogenase (NAD(+), L-l... 466 e-129
ref|ZP_00948710.1| saccharopine dehydrogenase (NAD+, L-lysi... 466 e-129
ref|ZP_00954164.1| saccharopine dehydrogenase (NAD+, L-lysi... 461 e-128
ref|XP_760415.1| hypothetical protein UM04268.1 [Ustilago m... 460 e-128
ref|ZP_00959701.1| saccharopine dehydrogenase, putative [Ro... 449 e-124
ref|ZP_01446787.1| saccharopine dehydrogenase (NAD+, L-lysi... 448 e-124
ref|ZP_01746654.1| saccharopine dehydrogenase, putative [Sa... 446 e-123
ref|XP_001634023.1| predicted protein [Nematostella vectens... 442 e-122
ref|ZP_01154744.1| saccharopine dehydrogenase (NAD+, L-lysi... 439 e-121
ref|ZP_01219314.1| hypothetical saccharopine dehydrogenase ... 432 e-119
ref|XP_711455.1| saccharopine dehydrogenase [Candida albica... 430 e-119
ref|XP_001732779.1| hypothetical protein MGL_0554 [Malassez... 429 e-118
ref|YP_132774.1| hypothetical saccharopine dehydrogenase [P... 429 e-118
ref|NP_001011437.1| hypothetical protein LOC496923 [Xenopus... 426 e-117
ref|NP_001085980.1| MGC82978 protein [Xenopus laevis] >gi|4... 424 e-117
ref|NP_001103267.1| aminoadipate-semialdehyde synthase [Bos... 422 e-116
ref|YP_511957.1| Saccharopine dehydrogenase (NAD+, L-lysine... 422 e-116
ref|XP_684074.2| PREDICTED: similar to lysine ketoglutarate... 421 e-116
ref|XP_001842086.1| alpha-aminoadipic semialdehyde synthase... 420 e-116
ref|XP_001502225.1| PREDICTED: similar to lysine ketoglutar... 420 e-115
ref|XP_001370253.1| PREDICTED: similar to lysine ketoglutar... 419 e-115
ref|XP_416001.2| PREDICTED: hypothetical protein [Gallus ga... 419 e-115
ref|XP_539546.2| PREDICTED: similar to aminoadipate-semiald... 419 e-115
ref|NP_001094433.1| aminoadipate-semialdehyde synthase [Rat... 417 e-115
ref|NP_038958.2| aminoadipate-semialdehyde synthase precurs... 417 e-115
dbj|BAE22882.1| unnamed protein product [Mus musculus] 417 e-115
emb|CAA12114.1| lysine ketoglutarate reductase/saccharopine... 417 e-115
emb|CAA07619.2| lysine-ketoglutarate reductase /saccharopin... 413 e-113
ref|NP_005754.2| aminoadipate-semialdehyde synthase [Homo s... 413 e-113
ref|XP_001145257.1| PREDICTED: aminoadipate-semialdehyde sy... 412 e-113
ref|XP_001649464.1| saccharopine dehydrogenase [Aedes aegyp... 411 e-113
ref|XP_314728.3| AGAP008632-PA [Anopheles gambiae str. PEST... 411 e-113
ref|NP_001118002.1| lysine ketoglutarate reductase/saccharo... 409 e-112
ref|NP_609150.2| CG7144 CG7144-PA [Drosophila melanogaster]... 406 e-111
gb|AAR82744.1| SD02276p [Drosophila melanogaster] 406 e-111
emb|CAG01078.1| unnamed protein product [Tetraodon nigrovir... 405 e-111
ref|XP_001356475.1| GA20134-PA [Drosophila pseudoobscura] >... 405 e-111
ref|XP_001607166.1| PREDICTED: similar to ENSANGP0000001314... 395 e-108
ref|XP_971717.1| PREDICTED: similar to CG7144-PA [Tribolium... 393 e-107
ref|XP_624513.2| PREDICTED: similar to CG7144-PA [Apis mell... 389 e-106
ref|NP_822964.1| saccharopine dehydrogenase [Streptomyces a... 383 e-105
ref|XP_797286.2| PREDICTED: similar to saccharopine dehydro... 381 e-104
ref|YP_001535948.1| alanine dehydrogenase/PNT domain protei... 377 e-103
ref|XP_001672092.1| Hypothetical protein CBG13546 [Caenorha... 370 e-100
ref|ZP_01728427.1| hypothetical protein CY0110_25071 [Cyano... 368 e-100
ref|NP_499884.1| R02D3.1 [Caenorhabditis elegans] >gi|27363... 366 1e-99
ref|YP_001295405.1| Putative monofunctional lysine-ketoglut... 360 8e-98
ref|ZP_02182261.1| hypothetical protein FBALC1_04707 [Flavo... 354 5e-96
ref|ZP_02163121.1| hypothetical protein KAOT1_11306 [Kordia... 354 6e-96
ref|ZP_01121461.1| hypothetical saccharopine dehydrogenase ... 353 1e-95
ref|ZP_01891601.1| hypothetical protein SCB49_01387 [uniden... 352 3e-95
ref|YP_001805104.1| unknown [Cyanothece sp. ATCC 51142] >gi... 351 4e-95
ref|ZP_01253400.1| saccharopine dehydrogenase, putative [Ps... 350 1e-94
ref|YP_001197105.1| alanine dehydrogenase/PNT domain protei... 350 1e-94
ref|ZP_01054061.1| saccharopine dehydrogenase, putative [Te... 349 2e-94
ref|XP_001744925.1| predicted protein [Monosiga brevicollis... 349 2e-94
ref|ZP_00948992.1| hypothetical saccharopine dehydrogenase ... 348 3e-94
ref|ZP_01119038.1| saccharopine dehydrogenase, putative [Po... 348 5e-94
ref|XP_001630319.1| predicted protein [Nematostella vectens... 347 1e-93
ref|ZP_01734750.1| hypothetical protein FBBAL38_11809 [Flav... 346 2e-93
ref|ZP_01202579.1| putative dehydrogenase [Flavobacteria ba... 345 2e-93
ref|ZP_01061856.1| hypothetical saccharopine dehydrogenase ... 345 3e-93
ref|YP_862590.1| lysine 2-oxoglutarate reductase [Gramella ... 342 4e-92
ref|ZP_01718580.1| putative saccharopine dehydrogenase [Alg... 336 1e-90
ref|YP_679948.1| hypothetical protein CHU_3369 [Cytophaga h... 336 2e-90
ref|ZP_01051455.1| putative saccharopine dehydrogenase [Cel... 334 7e-90
ref|ZP_01687098.1| hypothetical protein M23134_02084 [Micro... 333 1e-89
ref|ZP_00533414.1| Alanine dehydrogenase/PNT, C-terminal:Al... 329 2e-88
ref|XP_638394.1| aminoadipic semialdehyde synthase [Dictyos... 321 5e-86
gb|EEJ79866.1| alanine dehydrogenase [Kangiella koreensis D... 305 4e-81
gb|AAN14411.1| monofunctional lysine-ketoglutarate reductas... 300 2e-79
emb|CAO65167.1| unnamed protein product [Vitis vinifera] 299 2e-79
gb|AAN14410.1| bifunctional lysine-ketoglutarate reductase/... 298 3e-79
ref|XP_001889650.1| predicted protein [Laccaria bicolor S23... 283 2e-74
ref|XP_566629.1| saccharopine dehydrogenase [Cryptococcus n... 281 5e-74
ref|XP_778221.1| hypothetical protein CNBA2210 [Cryptococcu... 281 6e-74
ref|XP_001021580.1| Alanine dehydrogenase/PNT, N-terminal d... 279 2e-73
ref|ZP_02188470.1| hypothetical protein BAL199_04779 [alpha... 279 3e-73
gb|EAZ24849.1| hypothetical protein OsJ_008332 [Oryza sativ... 274 6e-72
gb|EAY87774.1| hypothetical protein OsI_009007 [Oryza sativ... 265 4e-69
ref|XP_001838392.1| hypothetical protein CC1G_12484 [Coprin... 263 1e-68
ref|XP_001620022.1| hypothetical protein NEMVEDRAFT_v1g6152... 174 1e-41
ref|XP_001634024.1| predicted protein [Nematostella vectens... 140 1e-31
ref|ZP_01264036.1| alanine dehydrogenase [Candidatus Pelagi... 139 3e-31
Sequences not found previously or not previously below threshold:
ref|NP_567914.1| LKR (SACCHAROPINE DEHYDROGENASE) [Arabidop... 289 2e-76
gb|AAB96826.1| lysine-ketoglutarate reductase/saccharopine ... 289 2e-76
gb|AAB96825.1| lysine-ketoglutarate reductase/saccharopine ... 289 2e-76
sp|Q9SMZ4|AASS_ARATH Alpha-aminoadipic semialdehyde synthas... 289 2e-76
gb|AAK97099.1|AF295389_1 monofunctional lysine-ketoglutarat... 289 2e-76
gb|AAB53975.1| lysine-ketoglutarate reductase/saccharopine ... 289 2e-76
ref|XP_001777036.1| predicted protein [Physcomitrella paten... 288 4e-76
ref|NP_001104873.1| lysine-ketoglutarate reductase/saccharo... 278 7e-73
ref|XP_001453750.1| hypothetical protein GSPATT00020034001 ... 224 7e-57
ref|XP_001456499.1| hypothetical protein GSPATT00022271001 ... 224 8e-57
ref|XP_001428538.1| hypothetical protein GSPATT00031371001 ... 215 5e-54
gb|ABF18958.1| lysine ketoglutarate reductase/saccharopine ... 209 4e-52
ref|ZP_01108359.1| hypothetical protein FB2170_01961 [Flavo... 180 1e-43
ref|YP_266230.1| alanine dehydrogenase [Candidatus Pelagiba... 138 9e-31
ref|NP_001048324.1| Os02g0783700 [Oryza sativa (japonica cu... 129 3e-28
ref|YP_065168.1| similar to cold-adapted alanine dehydrogen... 124 1e-26
ref|ZP_01104926.1| hypothetical protein FB2170_01970 [Flavo... 122 7e-26
ref|YP_001394062.1| Ald [Clostridium kluyveri DSM 555] >gi|... 121 7e-26
ref|ZP_02424229.1| hypothetical protein ALIPUT_00344 [Alist... 118 7e-25
ref|ZP_00513142.1| Alanine dehydrogenase and pyridine nucle... 117 1e-24
ref|ZP_01052096.1| putative alanine dehydrogenase [Tenaciba... 117 2e-24
gb|EDM15159.1| aminoadipate-semialdehyde synthase (predicte... 115 5e-24
ref|YP_873046.1| L-alanine dehydrogenase [Acidothermus cell... 115 5e-24
ref|YP_001917832.1| L-alanine dehydrogenase [Natranaerobius... 115 6e-24
ref|YP_001211208.1| alanine dehydrogenase [Pelotomaculum th... 115 7e-24
ref|YP_575010.1| alanine dehydrogenase [Chromohalobacter sa... 114 9e-24
ref|ZP_01872936.1| alanine dehydrogenase [Lentisphaera aran... 114 1e-23
ref|YP_001488077.1| alanine dehydrogenase [Bacillus pumilus... 114 1e-23
ref|ZP_01062209.1| putative alanine dehydrogenase [Flavobac... 113 2e-23
ref|ZP_02184200.1| stage V sporulation protein N (L-alanine... 113 2e-23
ref|ZP_00517716.1| Alanine dehydrogenase and pyridine nucle... 113 2e-23
ref|NP_372233.1| alanine dehydrogenase [Staphylococcus aure... 113 3e-23
ref|NP_764939.1| alanine dehydrogenase [Staphylococcus epid... 113 3e-23
ref|NP_374819.1| alanine dehydrogenase [Staphylococcus aure... 112 4e-23
ref|NP_646469.1| alanine dehydrogenase [Staphylococcus aure... 112 5e-23
ref|ZP_03987947.1| alanine dehydrogenase [Staphylococcus au... 112 6e-23
ref|YP_041174.1| alanine dehydrogenase 1 [Staphylococcus au... 112 6e-23
ref|NP_840123.1| alanine dehydrogenase [Nitrosomonas europa... 112 7e-23
ref|YP_417038.1| alanine dehydrogenase [Staphylococcus aure... 111 8e-23
ref|YP_001126767.1| Alanine dehydrogenase [Geobacillus ther... 111 9e-23
ref|YP_474564.1| alanine dehydrogenase [Synechococcus sp. J... 110 2e-22
ref|ZP_01164841.1| alanine dehydrogenase [Oceanospirillum s... 110 2e-22
ref|ZP_02323668.1| alanine dehydrogenase [Anaeromyxobacter ... 110 2e-22
ref|ZP_04009917.1| alanine dehydrogenase [Lactobacillus sal... 110 2e-22
ref|YP_075651.1| alanine dehydrogenase [Symbiobacterium the... 110 3e-22
ref|ZP_01891777.1| putative alanine dehydrogenase [unidenti... 110 3e-22
ref|YP_465316.1| L-alanine dehydrogenase [Anaeromyxobacter ... 109 3e-22
gb|EEJ86007.1| L-alanine dehydrogenase [Meiothermus ruber D... 109 3e-22
ref|YP_746463.1| alanine dehydrogenase [Nitrosomonas eutrop... 108 7e-22
ref|YP_005739.1| alanine dehydrogenase [Thermus thermophilu... 108 8e-22
ref|YP_906040.1| secreted L-alanine dehydrogenase Ald (40 k... 108 8e-22
ref|YP_001155448.1| alanine dehydrogenase [Polynucleobacter... 108 9e-22
ref|YP_001850232.1| secreted L-alanine dehydrogenase Ald (4... 108 9e-22
ref|ZP_02175777.1| alanine dehydrogenase [Anaeromyxobacter ... 108 9e-22
ref|ZP_01202668.1| alanine dehydrogenase [Flavobacteria bac... 108 9e-22
ref|NP_961822.1| Ald [Mycobacterium avium subsp. paratuberc... 108 9e-22
ref|YP_253131.1| alanine dehydrogenase [Staphylococcus haem... 108 1e-21
ref|YP_143482.1| alanine dehydrogenase [Thermus thermophilu... 108 1e-21
ref|YP_411850.1| alanine dehydrogenase [Nitrosospira multif... 108 1e-21
ref|ZP_02072824.1| hypothetical protein BACUNI_04278 [Bacte... 107 1e-21
ref|NP_302068.1| L-alanine dehydrogenase [Mycobacterium lep... 107 1e-21
ref|YP_882850.1| alanine dehydrogenase [Mycobacterium avium... 107 1e-21
ref|YP_963387.1| alanine dehydrogenase [Shewanella sp. W3-1... 107 2e-21
ref|ZP_01908911.1| alanine dehydrogenase [Plesiocystis paci... 107 2e-21
ref|YP_001192379.1| alanine dehydrogenase [Flavobacterium j... 107 2e-21
dbj|BAA77513.1| alanine dehydrogenase [Enterobacter aerogenes] 107 2e-21
ref|YP_869684.1| alanine dehydrogenase [Shewanella sp. ANA-... 107 2e-21
ref|YP_536656.1| Alanine dehydrogenase [Lactobacillus saliv... 106 3e-21
ref|YP_734091.1| alanine dehydrogenase [Shewanella sp. MR-4... 106 3e-21
ref|YP_001529018.1| alanine dehydrogenase [Desulfococcus ol... 106 3e-21
gb|AAL87460.1| alanine dehydrogenase [Shewanella sp. PA-43] 106 3e-21
ref|NP_391071.1| L-alanine dehydrogenase [Bacillus subtilis... 106 3e-21
ref|YP_477594.1| alanine dehydrogenase [Synechococcus sp. J... 106 4e-21
ref|YP_927645.1| alanine dehydrogenase [Shewanella amazonen... 105 4e-21
ref|ZP_02965739.1| alanine dehydrogenase [bacterium Ellin51... 105 4e-21
ref|YP_750481.1| alanine dehydrogenase [Shewanella frigidim... 105 6e-21
ref|YP_301147.1| alanine dehydrogenase [Staphylococcus sapr... 105 6e-21
ref|ZP_02434435.1| hypothetical protein BACSTE_00661 [Bacte... 105 6e-21
gb|AAC23578.1| alanine dehydrogenase [Shewanella sp. Ac10] 105 7e-21
ref|YP_001366419.1| alanine dehydrogenase [Shewanella balti... 105 8e-21
gb|AAP44334.1| alanine dehydrogenase [Thermus caldophilus] 105 8e-21
ref|ZP_01120364.1| putative alanine dehydrogenase [Robigini... 105 8e-21
ref|ZP_03900458.1| L-alanine dehydrogenase [Dyadobacter fer... 104 9e-21
ref|YP_148605.1| alanine dehydrogenase [Geobacillus kaustop... 104 9e-21
ref|YP_944887.1| alanine dehydrogenase [Psychromonas ingrah... 104 1e-20
ref|YP_002786543.1| putative alanine dehydrogenase (Alanine... 104 1e-20
ref|YP_080482.1| L-alanine dehydrogenase [Bacillus lichenif... 104 1e-20
ref|ZP_01118752.1| putative alanine dehydrogenase [Polariba... 104 1e-20
ref|YP_359521.1| alanine dehydrogenase [Carboxydothermus hy... 104 1e-20
ref|YP_001674437.1| alanine dehydrogenase [Shewanella halif... 104 1e-20
ref|YP_803715.1| Alanine dehydrogenase [Pediococcus pentosa... 104 1e-20
ref|ZP_02941837.1| alanine dehydrogenase [Cyanothece sp. PC... 103 2e-20
ref|YP_001327051.1| alanine dehydrogenase [Sinorhizobium me... 103 2e-20
ref|ZP_01731833.1| Alanine dehydrogenase and pyridine nucle... 103 2e-20
ref|ZP_02078507.1| hypothetical protein EUBDOL_02329 [Eubac... 103 2e-20
ref|YP_001760857.1| alanine dehydrogenase [Shewanella woody... 103 2e-20
ref|ZP_01736276.1| alanine dehydrogenase [Marinobacter sp. ... 103 2e-20
ref|YP_001621081.1| alanine dehydrogenase [Acholeplasma lai... 103 2e-20
ref|YP_001801454.1| alanine dehydrogenase [Cyanothece sp. A... 103 3e-20
ref|YP_098760.1| alanine dehydrogenase [Bacteroides fragili... 103 3e-20
ref|ZP_02931419.1| alanine dehydrogenase [Verrucomicrobium ... 103 3e-20
ref|YP_001450010.1| alanine dehydrogenase [Streptococcus go... 102 3e-20
ref|YP_001502090.1| alanine dehydrogenase [Shewanella peale... 102 4e-20
ref|YP_001094151.1| alanine dehydrogenase [Shewanella loihi... 102 4e-20
ref|ZP_01452344.1| alanine dehydrogenase [Mariprofundus fer... 102 4e-20
ref|ZP_03886500.1| L-alanine dehydrogenase [Gordonia bronch... 102 4e-20
ref|ZP_00738801.1| Alanine dehydrogenase [Bacillus thuringi... 102 5e-20
ref|YP_001473862.1| alanine dehydrogenase [Shewanella sedim... 102 5e-20
ref|ZP_00952239.1| alanine dehydrogenase [Oceanicaulis alex... 102 5e-20
ref|YP_001050520.1| alanine dehydrogenase [Shewanella balti... 102 5e-20
ref|ZP_01666824.1| alanine dehydrogenase [Thermosinus carbo... 102 6e-20
ref|YP_001376512.1| alanine dehydrogenase [Bacillus cereus ... 102 6e-20
ref|YP_001643400.1| alanine dehydrogenase [Bacillus weihens... 102 6e-20
ref|YP_001035553.1| Alanine dehydrogenase, putative [Strept... 102 7e-20
ref|NP_385730.1| PROBABLE ALANINE DEHYDROGENASE OXIDOREDUCT... 102 7e-20
ref|YP_001554753.1| alanine dehydrogenase [Shewanella balti... 102 7e-20
ref|YP_562748.1| alanine dehydrogenase [Shewanella denitrif... 102 7e-20
gb|EEJ89107.1| L-alanine dehydrogenase [Meiothermus silvanu... 102 7e-20
ref|ZP_02914793.1| alanine dehydrogenase [Geobacillus sp. W... 101 8e-20
ref|NP_337355.1| alanine dehydrogenase [Mycobacterium tuber... 101 8e-20
ref|YP_001647239.1| alanine dehydrogenase [Bacillus weihens... 101 9e-20
ref|NP_217296.1| SECRETED L-ALANINE DEHYDROGENASE ALD (40 K... 101 1e-19
pdb|2VHW|A Chain A, Crystal Structure Of Holo L-Alanine Deh... 101 1e-19
ref|YP_113082.1| alanine dehydrogenase [Methylococcus capsu... 101 1e-19
ref|YP_604242.1| alanine dehydrogenase [Deinococcus geother... 101 1e-19
ref|ZP_01723571.1| alanine dehydrogenase [Bacillus sp. B149... 101 1e-19
ref|YP_517218.1| hypothetical protein DSY0985 [Desulfitobac... 101 1e-19
ref|YP_001301040.1| alanine dehydrogenase [Bacteroides vulg... 101 1e-19
ref|ZP_01721568.1| putative alanine dehydrogenase [Algoriph... 100 1e-19
ref|ZP_02067293.1| hypothetical protein BACOVA_04297 [Bacte... 100 2e-19
ref|ZP_02585793.1| alanine dehydrogenase (L-alanine dehydro... 100 2e-19
ref|ZP_02522526.1| alanine dehydrogenase (L-alanine dehydro... 100 2e-19
ref|YP_002754767.1| alanine dehydrogenase [Acidobacterium c... 100 2e-19
ref|YP_886996.1| alanine dehydrogenase [Mycobacterium smegm... 100 2e-19
gb|ABR57171.1| alanine dehydrogenase [Staphylococcus xylosus] 100 2e-19
ref|ZP_01215557.1| alanine dehydrogenase [Psychromonas sp. ... 100 3e-19
ref|ZP_02420399.1| hypothetical protein ANACAC_03016 [Anaer... 100 3e-19
gb|AAC23577.1| alanine dehydrogenase [Carnobacterium sp. St2] 100 3e-19
ref|ZP_01049900.1| putative alanine dehydrogenase [Cellulop... 100 3e-19
ref|YP_174267.1| stage V sporulation protein N, alanine deh... 100 4e-19
ref|ZP_02883918.1| alanine dehydrogenase [Burkholderia gram... 99 4e-19
ref|ZP_01697384.1| alanine dehydrogenase [Bacillus coagulan... 99 4e-19
ref|NP_969291.1| hypothetical protein Bd2478 [Bdellovibrio ... 99 5e-19
ref|NP_827683.1| L-alanine dehydrogenase [Streptomyces aver... 99 5e-19
ref|YP_550034.1| alanine dehydrogenase [Polaromonas sp. JS6... 99 6e-19
ref|YP_002781576.1| alanine dehydrogenase [Rhodococcus opac... 99 6e-19
ref|YP_001185975.1| alanine dehydrogenase [Pseudomonas mend... 99 6e-19
emb|CAO90307.1| unnamed protein product [Microcystis aerugi... 99 6e-19
ref|YP_374584.1| Alanine dehydrogenase and pyridine nucleot... 99 6e-19
ref|ZP_01444021.1| alanine dehydrogenase [Roseovarius sp. H... 99 7e-19
ref|ZP_00740055.1| Alanine dehydrogenase [Bacillus thuringi... 99 7e-19
ref|NP_422368.1| alanine dehydrogenase [Caulobacter crescen... 99 7e-19
ref|YP_001736003.1| alanine dehydrogenase [Synechococcus sp... 99 7e-19
ref|NP_847074.1| alanine dehydrogenase [Bacillus anthracis ... 99 7e-19
ref|ZP_02262771.1| alanine dehydrogenase [Bacillus cereus A... 99 7e-19
ref|YP_001827236.1| putative L-alanine dehydrogenase [Strep... 99 7e-19
>pdb|2QRJ|A Chain A, Crystal Structure Of Sulfate-Bound Saccharopine
Dehydrogenase (L-Lys Forming) From Saccharomyces
Cerevisiae
pdb|2QRK|A Chain A, Crystal Structure Of Amp-Bound Saccharopine Dehydrogenase
(L-Lys Forming) From Saccharomyces Cerevisiae
pdb|2QRL|A Chain A, Crystal Structure Of Oxalylglycine-Bound Saccharopine
Dehydrogenase (L-Lys Forming) From Saccharomyces
Cerevisiae
Length = 394
Score = 625 bits (1614), Expect = e-177, Method: Composition-based stats.
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 22 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 81
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 82 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 141
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 142 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 201
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 202 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 261
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 262 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 321
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 322 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 381
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 382 DRHCARVKRSSRL 394
>ref|NP_012300.1| Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the
conversion of saccharopine to L-lysine, which is the
final step in the lysine biosynthesis pathway; Lys1p
[Saccharomyces cerevisiae]
sp|P38998|LYS1_YEAST Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
emb|CAA86194.1| lys1 [Saccharomyces cerevisiae]
gb|EDN61529.1| lysine requiring protein [Saccharomyces cerevisiae YJM789]
Length = 373
Score = 625 bits (1613), Expect = e-177, Method: Composition-based stats.
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 361 DRHCARVKRSSRL 373
>emb|CAA54551.1| saccharopine dehydrogenase (NAD+, L-lysine forming) [Saccharomyces
cerevisiae]
Length = 373
Score = 624 bits (1611), Expect = e-177, Method: Composition-based stats.
Identities = 372/373 (99%), Positives = 372/373 (99%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTT GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 301 PTVLVPTTVGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 361 DRHCARVKRSSRL 373
>pdb|2Q99|A Chain A, Crystal Structure Of Saccharopine Dehydrogenase From
Saccharomyces Cerevisiae
Length = 381
Score = 622 bits (1605), Expect = e-176, Method: Composition-based stats.
Identities = 370/373 (99%), Positives = 370/373 (99%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 9 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 68
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKE PETDTFPLVHEHIQFAHCYKDQAGWQNVL RFIKGHGTLYD
Sbjct: 69 AGSWKTAPRDRIIIGLKEXPETDTFPLVHEHIQFAHCYKDQAGWQNVLXRFIKGHGTLYD 128
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 129 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 188
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 189 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 248
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTN EKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 249 PQADIFINCIYLSKPIAPFTNXEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 308
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 309 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 368
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 369 DRHCARVKRSSRL 381
>ref|XP_446267.1| unnamed protein product [Candida glabrata]
sp|Q6FU27|LYS1_CANGA Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
emb|CAG59191.1| unnamed protein product [Candida glabrata CBS 138]
Length = 372
Score = 605 bits (1560), Expect = e-171, Method: Composition-based stats.
Identities = 301/371 (81%), Positives = 329/371 (88%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
+VTLHLR ETKPLE RAALTPTTVK LI KGFKIYVE+SPQS F I+EYR+AGAIIVP G
Sbjct: 2 SVTLHLRGETKPLEHRAALTPTTVKHLIGKGFKIYVEESPQSIFKIDEYRRAGAIIVPFG 61
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW +APRDRIIIGLKEMPE D FPLVHEHIQFAHCYKDQAGW++VL RFI G+GTLYDLE
Sbjct: 62 SWISAPRDRIIIGLKEMPEEDKFPLVHEHIQFAHCYKDQAGWKDVLRRFINGNGTLYDLE 121
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
FLE+D GRRVAAFGFYAGFAGAALG+ DWAFKQTH D EDLPAVSPYPNEKAL+KD+ K
Sbjct: 122 FLEDDNGRRVAAFGFYAGFAGAALGLADWAFKQTHKDSEDLPAVSPYPNEKALIKDIGKA 181
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
YK AL TGA+KP VLIIGALGRCGSGAID L KVG+P+ NI+KWDI+ETSRGGPF EI
Sbjct: 182 YKNALKTGAKKPKVLIIGALGRCGSGAIDFLKKVGLPEENIIKWDIQETSRGGPFPEIAA 241
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
+DIFINCIYLSKPIAPF N E LN P+R+LRTVVDVSADTTNPHNPIPIY +ATVFNKPT
Sbjct: 242 SDIFINCIYLSKPIAPFINYELLNKPDRKLRTVVDVSADTTNPHNPIPIYNIATVFNKPT 301
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V V T++GPKLSVISIDHLPSLLPREASEFF+HDLLPSLE LP R +PVWVRA+KLF+R
Sbjct: 302 VKVNTSSGPKLSVISIDHLPSLLPREASEFFAHDLLPSLEQLPSRHVSPVWVRAEKLFNR 361
Query: 363 HCARVKRSSRL 373
H AR R S+L
Sbjct: 362 HSARAIRESKL 372
>ref|XP_001387327.1| Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH) [Pichia
stipitis CBS 6054]
gb|EAZ63304.1| Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH) [Pichia
stipitis CBS 6054]
Length = 371
Score = 602 bits (1552), Expect = e-170, Method: Composition-based stats.
Identities = 271/369 (73%), Positives = 307/369 (83%), Gaps = 1/369 (0%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
V LHLRAETKPLE RAALTPTT K+LI GFKI+VE S QSTF I EY QAGA IVP
Sbjct: 3 TPVILHLRAETKPLEHRAALTPTTTKQLIDAGFKIFVEKSSQSTFAIEEYEQAGATIVPE 62
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWK AP+DRIIIGLKE+PE +TFPLVHEHIQFAHCYKDQ GW++VL RF G+GTLYDL
Sbjct: 63 GSWKEAPKDRIIIGLKELPEDETFPLVHEHIQFAHCYKDQGGWKDVLSRFPAGNGTLYDL 122
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
EFLEND GRRVAAFGFYAGFAGAA+GVRDWAFKQ H D E+L ++PYPNE L+ DV K
Sbjct: 123 EFLENDTGRRVAAFGFYAGFAGAAIGVRDWAFKQLHPDSENLGGLTPYPNEDGLIADVKK 182
Query: 182 DYKEAL-ATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
D + AL G + PT L+IGALGRCGSGAIDL KVGIP+ NI KWDI+ET++GGPF EI
Sbjct: 183 DLEAALQKNGGQYPTTLVIGALGRCGSGAIDLFRKVGIPEENITKWDIQETAKGGPFKEI 242
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
++DIF+NCIYLS+PI PF + LN P+R+LR +VDVSADTTNPHNPIP+Y++ATVFN
Sbjct: 243 VESDIFVNCIYLSQPIPPFIDYSSLNVPDRKLRIIVDVSADTTNPHNPIPVYSIATVFND 302
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTV+V TTAGPKLSV SIDHLPSLLPREASEFFS DLLPSL LP+R+TAPVW RAK LF
Sbjct: 303 PTVVVETTAGPKLSVCSIDHLPSLLPREASEFFSRDLLPSLLQLPERQTAPVWTRAKALF 362
Query: 361 DRHCARVKR 369
D+H AR+
Sbjct: 363 DKHVARLSE 371
>ref|XP_454310.1| unnamed protein product [Kluyveromyces lactis]
emb|CAG99397.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
Length = 372
Score = 598 bits (1544), Expect = e-169, Method: Composition-based stats.
Identities = 283/371 (76%), Positives = 322/371 (86%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
+VTLHLRAETKPLEAR ALTPTT KKL+ KGFKI+VE+S QS F+I EY++ GA IVP G
Sbjct: 2 SVTLHLRAETKPLEARTALTPTTTKKLLDKGFKIFVEESSQSAFDIEEYKKVGATIVPEG 61
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYK+QAGW++VL RF +G+G LYDLE
Sbjct: 62 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKNQAGWEDVLSRFKRGNGVLYDLE 121
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
FLENDQGRRVAAFGFYAGFAGAA+G+RDWAFKQTHSD E+L A+ PY NE+A++KDV +D
Sbjct: 122 FLENDQGRRVAAFGFYAGFAGAAVGIRDWAFKQTHSDSENLGAIEPYENEEAMIKDVRRD 181
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
Y+ AL GARKP VLIIGALGRCGSGA DLL K G+P+ NI+KWD+KET+RGGPF EI
Sbjct: 182 YQLALKRGARKPKVLIIGALGRCGSGAADLLRKCGLPEENIIKWDMKETARGGPFQEIAD 241
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
AD+FINCIYLSKPI PF N E LN P RRLRTVVDVSADTTNPHNP+PIYT+ T F+ PT
Sbjct: 242 ADVFINCIYLSKPIPPFINNELLNKPTRRLRTVVDVSADTTNPHNPVPIYTINTTFDAPT 301
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V VPTT GPKLSV SIDHLPSLLP+EASE FS DLLPSLE LPQR TA VWV+A+ L+++
Sbjct: 302 VQVPTTVGPKLSVCSIDHLPSLLPKEASESFSRDLLPSLEQLPQRATASVWVKARNLYEK 361
Query: 363 HCARVKRSSRL 373
A+V R+S+L
Sbjct: 362 FAAKVGRTSKL 372
>ref|XP_001523078.1| saccharopine dehydrogenase [Lodderomyces elongisporus NRRL YB-4239]
gb|EDK47443.1| saccharopine dehydrogenase [Lodderomyces elongisporus NRRL YB-4239]
Length = 370
Score = 597 bits (1541), Expect = e-169, Method: Composition-based stats.
Identities = 274/370 (74%), Positives = 308/370 (83%), Gaps = 3/370 (0%)
Query: 1 MA--AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAII 58
M+ V LHLRAETKPLEARAALTPTT K+L+ GFK+YVE+S QSTFN EY GA I
Sbjct: 1 MSSNPVILHLRAETKPLEARAALTPTTTKQLLDAGFKVYVEESSQSTFNAKEYEAVGAEI 60
Query: 59 VPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTL 118
VP GSWK AP+DRII GLKE+PE DTFPLVH HIQFAHCYK+QAGW+ VL RF G+GTL
Sbjct: 61 VPEGSWKDAPKDRIIFGLKELPENDTFPLVHTHIQFAHCYKNQAGWEKVLGRFPAGNGTL 120
Query: 119 YDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKD 178
YDLEFLENDQGRRVAAFGFYAGFAGAA+GV DWAFKQ H DDE+LP VSPYPNE AL+KD
Sbjct: 121 YDLEFLENDQGRRVAAFGFYAGFAGAAIGVLDWAFKQLHGDDENLPGVSPYPNEDALIKD 180
Query: 179 VTKDYKEALAT-GARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPF 237
V + +ALA G + PT L+IGALGRCGSGAIDL KVGIPD N+ KWD+ ET++GGPF
Sbjct: 181 VKTELDKALAKNGGKYPTALVIGALGRCGSGAIDLFKKVGIPDDNVAKWDMAETAKGGPF 240
Query: 238 DEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATV 297
EI +IF+NCIYLS+PIAPF N E LN P R+L T+VDVSADTTNPHNPIP+Y +ATV
Sbjct: 241 KEIVDTNIFVNCIYLSQPIAPFINYETLNVPERKLTTIVDVSADTTNPHNPIPVYEIATV 300
Query: 298 FNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAK 357
FN PTV V TTAGPKLSV SIDHLPSLLPREASEFFS DL+PSL LP+R TAPVWVRAK
Sbjct: 301 FNDPTVPVKTTAGPKLSVCSIDHLPSLLPREASEFFSKDLMPSLLQLPERDTAPVWVRAK 360
Query: 358 KLFDRHCARV 367
+LFD++ AR+
Sbjct: 361 QLFDKNVARL 370
>ref|XP_457987.1| hypothetical protein DEHA0C07832g [Debaryomyces hansenii CBS767]
emb|CAG86045.1| unnamed protein product [Debaryomyces hansenii CBS767]
Length = 370
Score = 596 bits (1537), Expect = e-168, Method: Composition-based stats.
Identities = 267/367 (72%), Positives = 309/367 (84%), Gaps = 1/367 (0%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
+ VTLHLRAETKPLEARAALTP+T K+L+ GFK+YVE S QSTF+ +EY + GA IVP
Sbjct: 3 SPVTLHLRAETKPLEARAALTPSTTKQLLDAGFKVYVEKSSQSTFDADEYEKVGATIVPE 62
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWK AP+DRII GLKE+PE +TFPLVHEHIQFAHCYKDQ GW++VL RF +G GTLYDL
Sbjct: 63 GSWKEAPKDRIIFGLKELPEDETFPLVHEHIQFAHCYKDQGGWKDVLRRFPEGKGTLYDL 122
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
EFLENDQGRRVAAFGFYAGFAGAA+GV DWAFKQTHSD+EDL V+PYPNE L+ DV K
Sbjct: 123 EFLENDQGRRVAAFGFYAGFAGAAIGVMDWAFKQTHSDNEDLRGVTPYPNEDELIADVKK 182
Query: 182 DYKEALAT-GARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
EAL G P L+IGALGRCGSGA+D KVGIPD ++KWD+KET++GGPF EI
Sbjct: 183 VLDEALKKNGGEYPQCLVIGALGRCGSGALDFFKKVGIPDEKLIKWDMKETAKGGPFQEI 242
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
Q+DIF+NCIYLS+PI PF + E LN P+R+LRT+VDVSADTTNPHNPIP+Y++ATVFN
Sbjct: 243 VQSDIFVNCIYLSQPIPPFIDYEGLNVPDRKLRTIVDVSADTTNPHNPIPVYSIATVFND 302
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTV V T+AGPKLSV SIDHLPSLLPREASEFF+ DL+PSL LP R T+PVWVRAK+LF
Sbjct: 303 PTVPVETSAGPKLSVCSIDHLPSLLPREASEFFAKDLMPSLLELPNRDTSPVWVRAKQLF 362
Query: 361 DRHCARV 367
D+H AR+
Sbjct: 363 DKHVARL 369
>ref|XP_001643683.1| hypothetical protein Kpol_1057p13 [Vanderwaltozyma polyspora DSM
70294]
gb|EDO15825.1| hypothetical protein Kpol_1057p13 [Vanderwaltozyma polyspora DSM
70294]
Length = 371
Score = 587 bits (1515), Expect = e-166, Method: Composition-based stats.
Identities = 280/371 (75%), Positives = 316/371 (85%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
TLHLRAETKPLEARAALTP+TVK LI KGFKIYVE+SPQS FN++EYR+ GA IVP G
Sbjct: 1 MTTLHLRAETKPLEARAALTPSTVKSLIKKGFKIYVEESPQSVFNVDEYRRCGATIVPFG 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW +APRDRIIIGLKEMPE D FPLVH+HIQFAHCYKDQ GW+ VL RFI G GTLYDLE
Sbjct: 61 SWISAPRDRIIIGLKEMPEEDVFPLVHDHIQFAHCYKDQEGWEKVLRRFINGQGTLYDLE 120
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
FLE+D G+RVAAFGFYAGFAGAALG++DWAFK+TH D EDL A++PYPNEKAL++D++ +
Sbjct: 121 FLEDDNGKRVAAFGFYAGFAGAALGLKDWAFKKTHDDSEDLGALTPYPNEKALLRDISHE 180
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
YK+AL TGA+ P VLIIGALGRCGSGAID L K+GIP NI+KWD++ET++GGPF EI
Sbjct: 181 YKQALKTGAKAPKVLIIGALGRCGSGAIDFLTKIGIPQENIIKWDMQETAKGGPFQEIVD 240
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
DIF+NCIYLSKPI PF NM LN +R L TVVDVSADTTNP+NPIPIY +ATVFNKPT
Sbjct: 241 TDIFVNCIYLSKPIPPFVNMSMLNQDSRHLTTVVDVSADTTNPYNPIPIYNIATVFNKPT 300
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V VPT GPKLSVISIDHLPSL+PREASE F+ DLLPSLELLP R APVW RA LF+R
Sbjct: 301 VTVPTKKGPKLSVISIDHLPSLMPREASEAFAKDLLPSLELLPNRHVAPVWTRAYSLFNR 360
Query: 363 HCARVKRSSRL 373
H AR RSS+L
Sbjct: 361 HSARAYRSSKL 371
>sp|P43065|LYS1_CANAL Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAA21362.1| saccharopine dehydrogenase
Length = 382
Score = 580 bits (1497), Expect = e-164, Method: Composition-based stats.
Identities = 262/379 (69%), Positives = 306/379 (80%), Gaps = 10/379 (2%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
+ V LHLRAETKPLEARAALTP+T K+L+ GF+IYVE+S QSTF+I EY GA IVP
Sbjct: 4 SPVILHLRAETKPLEARAALTPSTTKQLLDAGFEIYVEESSQSTFDIKEYEAVGAKIVPE 63
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWKTAP++RII GLKE+PE +TFPL+HEHIQFAHCYKDQAGWQ+VL RF +G+G LYDL
Sbjct: 64 GSWKTAPKERIIFGLKELPENETFPLIHEHIQFAHCYKDQAGWQDVLKRFPQGNGILYDL 123
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDED---------LPAVSPYPNE 172
EFLENDQGRRVAAFGFYAGFAGAA+GV DW+FKQ + + + LP V+PYPNE
Sbjct: 124 EFLENDQGRRVAAFGFYAGFAGAAIGVLDWSFKQLNGNTKGTKGEGEGGELPGVTPYPNE 183
Query: 173 KALVKDVTKDYKEAL-ATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKET 231
L+KDV + ++AL G + P L+IGALGRCGSGAIDL K+GIPD NI KWD+ ET
Sbjct: 184 NELIKDVKIELEKALTKNGGQYPKCLVIGALGRCGSGAIDLFKKIGIPDDNIAKWDMAET 243
Query: 232 SRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPI 291
++GGPF EI +DIFINCIYLSKPI PF N E LNN NR+L T+VDVSADTTNPHNPIP+
Sbjct: 244 AKGGPFQEIVDSDIFINCIYLSKPIPPFINKEILNNENRKLTTIVDVSADTTNPHNPIPV 303
Query: 292 YTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAP 351
Y +ATVFN+PTV V GPKLSV SIDHLPSLLPREASEFF+ DL+PSL LP R T+P
Sbjct: 304 YEIATVFNEPTVEVKLDKGPKLSVCSIDHLPSLLPREASEFFAKDLMPSLLELPNRDTSP 363
Query: 352 VWVRAKKLFDRHCARVKRS 370
VWVRAK+LFD+H AR+ +
Sbjct: 364 VWVRAKQLFDKHVARLDKE 382
>ref|XP_001213891.1| hypothetical protein ATEG_04713 [Aspergillus terreus NIH2624]
gb|EAU35160.1| hypothetical protein ATEG_04713 [Aspergillus terreus NIH2624]
Length = 988
Score = 571 bits (1474), Expect = e-161, Method: Composition-based stats.
Identities = 213/377 (56%), Positives = 265/377 (70%), Gaps = 6/377 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M + + LRAETKP EAR+ALTPTT K LI G+ + VE S Q F +E+ + GA +V
Sbjct: 612 MPSNKIWLRAETKPAEARSALTPTTAKALIDAGYDVTVERSKQRIFEDDEFPKIGAKLVE 671
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK Q GW+ VL R+ +G GTL
Sbjct: 672 EGSWVKDAPKDAFILGLKELPEDD-FPLEHVHISFAHCYKQQGGWEKVLSRWPRGGGTLL 730
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP PY N+ L++ V
Sbjct: 731 DLEFLTDDAGRRVAAFGYSAGYAGSALAVKNWAWQLTHPEGEPLPGEVPYANQDLLIQSV 790
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + R P VL+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 791 KESLEAGKKASGRSPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDMEETKKGGPFRE 850
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIF+NCIYLS PI PF N E L++PNRRL + DVSADTTNPHNPIP+YTV T F
Sbjct: 851 IIEDADIFVNCIYLSSPIPPFLNGETLSSPNRRLSVICDVSADTTNPHNPIPVYTVTTTF 910
Query: 299 NKPTVLV---PTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
++PTV V T GP LSVISIDHLPSLLPRE+SE FS LLPSL L + A VW +
Sbjct: 911 DRPTVPVILPAGTQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDWQNARVWKQ 970
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF A + S R
Sbjct: 971 AEDLFKEKVATLPESMR 987
>ref|XP_660477.1| hypothetical protein AN2873.2 [Aspergillus nidulans FGSC A4]
gb|EAA63444.1| hypothetical protein AN2873.2 [Aspergillus nidulans FGSC A4]
Length = 1026
Score = 570 bits (1469), Expect = e-161, Method: Composition-based stats.
Identities = 205/378 (54%), Positives = 268/378 (70%), Gaps = 6/378 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M + + LRAETKP EAR+ALTPTT K LI G+++ VE S Q F+ +E+ + GA +V
Sbjct: 1 MGSNKIWLRAETKPAEARSALTPTTCKALIDAGYEVTVERSTQRIFDDDEFAKVGAPLVE 60
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK+QAGW+ VL R+ +G G L
Sbjct: 61 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKEQAGWEKVLSRWPRGGGVLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFGF AG+AGAAL V++WA++ TH + E L PY N+ L++ V
Sbjct: 120 DLEFLTDDAGRRVAAFGFSAGYAGAALAVKNWAWQLTHPEGEPLAGEKPYANQDLLIQSV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + + P +L+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 180 KESLQAGQKQSGKSPKILVIGALGRCGKGAVQLAKDVGIPESDIIQWDMEETKKGGPFKE 239
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIF+NCIYLS I F N+E L+ P+RRL + DVSADTTNP+NPIP+Y + T F
Sbjct: 240 IVEDADIFVNCIYLSSKIPHFVNVESLSTPSRRLSVICDVSADTTNPNNPIPVYNITTTF 299
Query: 299 NKPTVLVPT---TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV V T G LSVISIDHLPSLLPRE+SE FS L+PSL L R+ A VW +
Sbjct: 300 DKPTVPVTLPNGTQGTPLSVISIDHLPSLLPRESSEMFSEALMPSLLQLKDRENARVWKQ 359
Query: 356 AKKLFDRHCARVKRSSRL 373
A+ LF++ A + +++ L
Sbjct: 360 AEDLFNQKVATLPQTAEL 377
>ref|XP_001482345.1| hypothetical protein PGUG_05365 [Pichia guilliermondii ATCC 6260]
gb|EDK41267.1| hypothetical protein PGUG_05365 [Pichia guilliermondii ATCC 6260]
Length = 370
Score = 568 bits (1464), Expect = e-160, Method: Composition-based stats.
Identities = 254/367 (69%), Positives = 304/367 (82%), Gaps = 1/367 (0%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
A V+LHLRAETKPLEARA L+P+ K+L+ GFK+YVE S QSTF+ +EY + GA IVP
Sbjct: 3 APVSLHLRAETKPLEARAGLSPSVTKELLDAGFKVYVEKSSQSTFDADEYAKVGAEIVPE 62
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWK AP+DRII GLK +PE +TFPLVHEHIQFAHCYKDQAGW++VL RF G+GTLYDL
Sbjct: 63 GSWKEAPKDRIIYGLKALPEDETFPLVHEHIQFAHCYKDQAGWKDVLSRFPAGNGTLYDL 122
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
EFL ND+GRRVAAFGFYAGFAGAA+G++DWAFKQTH+D+E+L V+PY E+ L+KDV +
Sbjct: 123 EFLVNDEGRRVAAFGFYAGFAGAAIGLKDWAFKQTHADNEELRGVTPYATEEELIKDVKE 182
Query: 182 DYKEALAT-GARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
D ALA G + P L+IGALGRCGSGA+ L K GIPD IL+WD+KET+RGGPF+EI
Sbjct: 183 DLDAALAKNGGKYPQCLVIGALGRCGSGAVSLFKKAGIPDEKILQWDMKETARGGPFEEI 242
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+DIFINCIYLS+PI PF + E LN+ R+LRT+VDVSADTTNP+NPIP+YTV T F+K
Sbjct: 243 TDSDIFINCIYLSQPIPPFVSSETLNSEKRKLRTIVDVSADTTNPNNPIPVYTVITDFDK 302
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PT LV TTAGPKLSV SIDHLPSL+PREASE F+ DLLP+L LP R TAPV+ RAK+LF
Sbjct: 303 PTALVETTAGPKLSVCSIDHLPSLVPREASETFAKDLLPTLLQLPDRNTAPVYQRAKQLF 362
Query: 361 DRHCARV 367
++H AR+
Sbjct: 363 EKHVARL 369
>ref|XP_500931.1| YlLYS5 [Yarrowia lipolytica]
sp|P38997|LYS1_YARLI Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAA35248.1| saccharopine dehydrogenase
emb|CAG83182.1| YlLYS5 [Yarrowia lipolytica CLIB122]
Length = 369
Score = 566 bits (1460), Expect = e-159, Method: Composition-based stats.
Identities = 248/368 (67%), Positives = 289/368 (78%), Gaps = 1/368 (0%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
A V LHLRAETKPLE R+ALTPTT +KL+ GF+++VE SP F+ E+ GA +V
Sbjct: 3 APVKLHLRAETKPLEHRSALTPTTTRKLLDAGFEVFVEKSPLRIFDDQEFVDVGATLVEE 62
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSW +AP DR+IIGLKE+PE +FPL HEHIQFAHCYKDQ GW++VL RF G+GTLYDL
Sbjct: 63 GSWVSAPEDRMIIGLKELPEE-SFPLSHEHIQFAHCYKDQGGWKDVLSRFPAGNGTLYDL 121
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
EFLE+D GRRVAAFGF+AGFAGAA+GV WAF+QTH D E+LP VS YPNE LV + K
Sbjct: 122 EFLEDDNGRRVAAFGFHAGFAGAAIGVETWAFQQTHPDSENLPGVSAYPNETELVDKIKK 181
Query: 182 DYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIP 241
D A+ G++ PTVL+IGALGRCGSGAIDL KVGIP+ NI++WD+ ET +GGPF EI
Sbjct: 182 DLAAAVEKGSKLPTVLVIGALGRCGSGAIDLARKVGIPEENIIRWDMNETKKGGPFQEIA 241
Query: 242 QADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKP 301
ADIFINCIYLS+PI PF N + LN R+L +VDVSADTTNPHNP+P+YT+AT F+ P
Sbjct: 242 DADIFINCIYLSQPIPPFINYDLLNKETRKLSVIVDVSADTTNPHNPVPVYTIATTFDHP 301
Query: 302 TVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFD 361
TV V TTAGPKLSV SIDHLPSLLPREASE FS LLPSL LPQR TAPVW RAK LFD
Sbjct: 302 TVPVETTAGPKLSVCSIDHLPSLLPREASEAFSEALLPSLLQLPQRDTAPVWTRAKALFD 361
Query: 362 RHCARVKR 369
+H R+
Sbjct: 362 KHVLRIGE 369
>ref|NP_983569.1| ACR167Cp [Ashbya gossypii ATCC 10895]
sp|Q75BV4|LYS1_ASHGO Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAS51393.1| ACR167Cp [Ashbya gossypii ATCC 10895]
Length = 372
Score = 564 bits (1454), Expect = e-159, Method: Composition-based stats.
Identities = 263/373 (70%), Positives = 316/373 (84%), Gaps = 1/373 (0%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M+A+ LHLRAETKP+EARAALTPTTV+ L++ GFKIYVE+S QS F EY AGA +V
Sbjct: 1 MSAI-LHLRAETKPMEARAALTPTTVRTLVSHGFKIYVEESAQSVFEAAEYAAAGAEVVA 59
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW+ APR+RII+GLKE+PE DTFPL H HIQFAHCYK+Q+GW+ VL RF G G LYD
Sbjct: 60 TGSWRGAPRERIIVGLKELPEEDTFPLEHTHIQFAHCYKNQSGWREVLGRFQSGGGLLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL++D+GRRVAAFG+YAGFAGAALG+RDWA+KQTH+D EDLPAV+PY NE+ALV +V
Sbjct: 120 LEFLQDDRGRRVAAFGYYAGFAGAALGLRDWAWKQTHTDAEDLPAVAPYENEQALVSEVA 179
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
+EA GARKP VL+IGALGRCGSGA++LL + G+ D +I++WDI ET+RGGPF EI
Sbjct: 180 AACEEAYKKGARKPRVLVIGALGRCGSGAVELLRQCGLHDKHIIRWDIAETARGGPFPEI 239
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
ADIFINCIYLS+PIAPF NME L+ P+R+LRT+VDVSADTTNPHNP+P+Y VATVF+
Sbjct: 240 AAADIFINCIYLSQPIAPFINMELLDRPDRKLRTIVDVSADTTNPHNPVPVYNVATVFSS 299
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTV+VPT+ GPKLSVISIDHLPSLLPREASE F+ DLLPSL LP+R TAPVW+RAK+LF
Sbjct: 300 PTVVVPTSQGPKLSVISIDHLPSLLPREASEAFASDLLPSLLQLPERDTAPVWLRAKELF 359
Query: 361 DRHCARVKRSSRL 373
+HC R+ + +RL
Sbjct: 360 QQHCERLSKEARL 372
>ref|XP_001399884.1| hypothetical protein An02g07500 [Aspergillus niger]
emb|CAK37714.1| unnamed protein product [Aspergillus niger]
Length = 377
Score = 563 bits (1453), Expect = e-159, Method: Composition-based stats.
Identities = 207/377 (54%), Positives = 264/377 (70%), Gaps = 6/377 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F+ ++ + GA +V
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSTQRIFDDEDFAKIGAPLVE 60
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK Q GW+ VL R+ +G GTL
Sbjct: 61 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQGGWEQVLSRWPRGGGTLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP PY N+ AL++ V
Sbjct: 120 DLEFLTDDVGRRVAAFGWSAGYAGSALAVKNWAWQLTHPEGEPLPGEVPYINQDALIESV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
K ++ R P +L+IGALGRCGSGA+ L VGIPD++I++WDI+ET +GGPF E
Sbjct: 180 KKSLEDGKKQSGRSPKILVIGALGRCGSGAVQLAKDVGIPDSDIVRWDIEETKKGGPFRE 239
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + DI +NCIYLS I PF E L +P RRL + DVSADTTNPHNP+P+Y++ T F
Sbjct: 240 IVEDVDILVNCIYLSAQIPPFVTPETLTSPKRRLSVICDVSADTTNPHNPLPVYSITTTF 299
Query: 299 NKPTVLVPTTAGP---KLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV V G LSVISIDHLPSLLPRE+SE FS LLPSL L R+ A VW +
Sbjct: 300 DKPTVPVTLAGGNQVAGLSVISIDHLPSLLPRESSEMFSQALLPSLLQLKDRQNARVWKQ 359
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF+ A + S R
Sbjct: 360 AEDLFNEKVATLPESLR 376
>ref|XP_754450.1| saccharopine dehydrogenase Lys1 [Aspergillus fumigatus Af293]
gb|EAL92412.1| saccharopine dehydrogenase Lys1, putative [Aspergillus fumigatus
Af293]
gb|EDP52582.1| saccharopine dehydrogenase Lys1, putative [Aspergillus fumigatus
A1163]
Length = 374
Score = 561 bits (1448), Expect = e-158, Method: Composition-based stats.
Identities = 212/377 (56%), Positives = 269/377 (71%), Gaps = 9/377 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F++ Q GA +V
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSRQRIFDV---VQIGAPLVE 57
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK QAGW+ VL R+ +G GTL
Sbjct: 58 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQAGWEKVLSRWPRGGGTLL 116
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL ++ GRRVAAFG+ AG+AG+AL +++WA++ TH + E LP +PY N+ L++ V
Sbjct: 117 DLEFLTDETGRRVAAFGYSAGYAGSALAIKNWAWQLTHPEGEPLPGETPYANQDLLIESV 176
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + R P VL+IGALGRCG GA+ L VGIP+++I++WDI+ET +GGPF E
Sbjct: 177 KESLESGKKLSGRPPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDIEETKKGGPFRE 236
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIFINCIYLS I PF N E L++PNRRL + DVSADTTNP+NPIP+Y++ T F
Sbjct: 237 IVEDADIFINCIYLSAKIPPFVNTETLSSPNRRLSVICDVSADTTNPNNPIPVYSITTTF 296
Query: 299 NKPTVLVP---TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV VP GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A VW +
Sbjct: 297 DKPTVTVPLPELAQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDRKNARVWKQ 356
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF+ A + S R
Sbjct: 357 AEDLFNEKVATLPESMR 373
>ref|XP_001263295.1| saccharopine dehydrogenase Lys1, putative [Neosartorya fischeri
NRRL 181]
gb|EAW21398.1| saccharopine dehydrogenase Lys1, putative [Neosartorya fischeri
NRRL 181]
Length = 374
Score = 561 bits (1446), Expect = e-158, Method: Composition-based stats.
Identities = 211/377 (55%), Positives = 269/377 (71%), Gaps = 9/377 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F++ Q GA +V
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSTQRIFDV---VQIGAPLVE 57
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK QAGW+ VL R+ +G GTL
Sbjct: 58 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQAGWEKVLSRWPRGGGTLL 116
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFG+ AG+AG+AL +++WA++ TH + E LP +PY N+ L++ V
Sbjct: 117 DLEFLTDDTGRRVAAFGYSAGYAGSALAIKNWAWQLTHPEGEPLPGETPYANQDLLIESV 176
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + R P VL+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 177 KESLESGKKLSGRPPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDLEETKKGGPFRE 236
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIFINCIYLS I PF N E L++P RRL + DVSADTTNP+NPIP+Y++ T F
Sbjct: 237 IVEDADIFINCIYLSAKIPPFVNTETLSSPKRRLSVICDVSADTTNPNNPIPVYSITTTF 296
Query: 299 NKPTVLVPTTA---GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV VP + GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A VW +
Sbjct: 297 DKPTVTVPLSERAQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDRKNARVWEQ 356
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF+ A + S R
Sbjct: 357 AEDLFNEKVATLPESIR 373
>ref|XP_001246345.1| hypothetical protein CIMG_00116 [Coccidioides immitis RS]
gb|EAS34762.1| hypothetical protein CIMG_00116 [Coccidioides immitis RS]
Length = 385
Score = 557 bits (1437), Expect = e-157, Method: Composition-based stats.
Identities = 203/384 (52%), Positives = 256/384 (66%), Gaps = 15/384 (3%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAG 55
MA TLHLRAE K LE R+ALTP+T + LI G+ I VE SP + F E+ +AG
Sbjct: 1 MAGTTLHLRAEDKILEHRSALTPSTTRALIDAGYNIKVERSPTSALRKRIFPDEEFEKAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +V GSW AP+D II+GLKE+ ET FPLVH+H+ FAHC+K+Q GW+ L R+ +G
Sbjct: 61 AELVAEGSWVNAPKDSIIVGLKELDETKDFPLVHDHVTFAHCFKNQGGWEKALGRWSRGG 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
G LYDLEFL++D GRRVAAFG++AGFAGAAL ++ WA++ H D LP V
Sbjct: 121 GVLYDLEFLQDDSGRRVAAFGYHAGFAGAALSLKTWAWQLEHPDGTPLPGVDEFTGGKGY 180
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE +V + D + RKP VLIIGALGRCG GA+D K G +IL+WD+
Sbjct: 181 YVNEDEMVNQIRADIERGAKIAGRKPRVLIIGALGRCGRGAVDACVKAG--CEDILRWDM 238
Query: 229 KETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNP 288
ET++GGPF EI ++DIFINCIYL+ I F + E L +PNR+L V DVS DTTNP+NP
Sbjct: 239 AETAKGGPFTEIVESDIFINCIYLTSKIPSFVDEESLKSPNRKLSVVCDVSCDTTNPNNP 298
Query: 289 IPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRK 348
IPIY V T F+KPT+ + T P LSVISIDHLPSLLP E+SE FS DLLPS+ + R
Sbjct: 299 IPIYNVNTTFDKPTLQLNYT-NPPLSVISIDHLPSLLPAESSEAFSTDLLPSMLEIKNRT 357
Query: 349 TAPVWVRAKKLFDRHCARVKRSSR 372
+ PVW RA+KL+ + +
Sbjct: 358 SHPVWQRAEKLYREKVQTLPAELQ 381
>sp|Q870G1|LYS1_EMENI Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAL23682.1| putative saccharopine dehydrogenase [Emericella nidulans]
Length = 375
Score = 556 bits (1435), Expect = e-157, Method: Composition-based stats.
Identities = 204/376 (54%), Positives = 265/376 (70%), Gaps = 6/376 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M + + LRAETKP EAR+ALTPTT K LI G+++ VE S Q F+ + Q GA +V
Sbjct: 1 MGSNKIWLRAETKPAEARSALTPTTCKALIDAGYEVTVERSTQRIFDGKIFVQVGAPLVE 60
Query: 61 AGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW K AP+D I+GLKE+PE D FPL H HI FAHCYK+QAGW+ VL R+ +G G L
Sbjct: 61 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKEQAGWEKVLSRWPRGGGVLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFGF AG+AGAAL V++WA++ TH + E L PY N+ L++ V
Sbjct: 120 DLEFLTDDAGRRVAAFGFSAGYAGAALAVKNWAWQLTHPEGEPLAGEKPYANQDLLIQSV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + + P +L+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 180 KESLQAGQKQSGKSPKILVIGALGRCGKGAVQLAKDVGIPESDIIQWDMEETKKGGPFKE 239
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIF+NCIYLS I F N+E L+ P+RRL + DVSADTTNP+NPIP+Y + T F
Sbjct: 240 IVEDADIFVNCIYLSSKIPHFVNVESLSTPSRRLSVICDVSADTTNPNNPIPVYNITTTF 299
Query: 299 NKPTVLVPT---TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV V T G LSVISIDHLPSLLPRE+SE FS L+PSL L R+ A VW +
Sbjct: 300 DKPTVPVTLPNGTQGTPLSVISIDHLPSLLPRESSEMFSEALMPSLLQLKDRENARVWKQ 359
Query: 356 AKKLFDRHCARVKRSS 371
A+ LF++ A + +++
Sbjct: 360 AEDLFNQKVATLPQTA 375
>ref|XP_001271170.1| saccharopine dehydrogenase Lys1, putative [Aspergillus clavatus
NRRL 1]
gb|EAW09744.1| saccharopine dehydrogenase Lys1, putative [Aspergillus clavatus
NRRL 1]
Length = 380
Score = 556 bits (1434), Expect = e-156, Method: Composition-based stats.
Identities = 210/381 (55%), Positives = 266/381 (69%), Gaps = 11/381 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINE----YRQAGA 56
M++ + LRAETKP EAR+ALTPTT K L+ G+ + VE S Q F+ + Y GA
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYDVTVERSTQRIFDGEDNILSYL-IGA 59
Query: 57 IIVPAGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
+V GSW K AP+D ++GLKE+PE D FPL H HI FAHCYK+Q GW+ VL R+ +G
Sbjct: 60 PLVEEGSWVKDAPKDAYVLGLKELPEDD-FPLEHVHISFAHCYKEQGGWEKVLSRWPRGG 118
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKAL 175
GTL DLEFL +D GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP +PY N+ L
Sbjct: 119 GTLLDLEFLTDDVGRRVAAFGYSAGYAGSALAVKNWAWQLTHPEGEPLPGETPYENQDLL 178
Query: 176 VKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGG 235
+ V + + + P VL+IGALGRCG GA+ L VGIP+++I++WDI+ET +GG
Sbjct: 179 IASVKESLEVGKKQSGKSPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDIEETKKGG 238
Query: 236 PFDEIPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTV 294
PF EI + DIF+NCIYLS I PF N E L+ PNRRL + DVSADTTNPHNPIP+Y++
Sbjct: 239 PFREIVEDVDIFVNCIYLSAKIPPFVNAETLSTPNRRLSVICDVSADTTNPHNPIPVYSI 298
Query: 295 ATVFNKPTVLVPTTA---GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAP 351
T F+KPTV V +A GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A
Sbjct: 299 TTTFDKPTVPVTLSAGAQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDRKNAR 358
Query: 352 VWVRAKKLFDRHCARVKRSSR 372
VW +A+ LF+ A + S R
Sbjct: 359 VWKQAEDLFNEKVATLPESMR 379
>ref|NP_592972.1| saccharopine dehydrogenase [NAD+, L-lysine forming] (PMID 3142867)
[Schizosaccharomyces pombe]
sp|Q09694|LYS1_SCHPO Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
emb|CAB61467.1| saccharopine dehydrogenase [NAD+, L-lysine forming] (PMID 3142867)
[Schizosaccharomyces pombe]
Length = 368
Score = 552 bits (1424), Expect = e-155, Method: Composition-based stats.
Identities = 213/369 (57%), Positives = 261/369 (70%), Gaps = 3/369 (0%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M A L LRAETKPLE R+ALTP T K L GF+I +E S Q F E+ + G +VP
Sbjct: 1 MVAPHLWLRAETKPLEERSALTPRTAKILADAGFQITIERSSQRAFKDKEFERLGFPMVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW+ AP+D IIGLKE+PE D PL H HIQFAHCYK+Q GW+ VL RF G+G LYD
Sbjct: 61 EGSWRHAPKDAYIIGLKELPENDNSPLKHTHIQFAHCYKNQEGWREVLSRFPAGNGLLYD 120
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL++D GRRVAAFG++AGFAG+A+ WA + H + + PA+ P+PNEK+LV+ V
Sbjct: 121 LEFLQDDNGRRVAAFGYHAGFAGSAISCLVWAHQLLHPN-KQFPAIRPFPNEKSLVRHVA 179
Query: 181 KDYKEALAT-GARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + AL + P +L+IGALGRCG+GA DL K+GIP NIL+WDI ET +GGPF E
Sbjct: 180 RQVRLALKKNNNQYPRILVIGALGRCGTGACDLASKIGIPFDNILRWDINETKKGGPFTE 239
Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
I ++DIF+NCIYLS PI F +E LN PNR+LR V DVS DTTNP+NPIPIY V T F+
Sbjct: 240 ITESDIFVNCIYLSMPIPKFCTVESLNVPNRKLRVVCDVSCDTTNPNNPIPIYNVNTTFD 299
Query: 300 KPTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKK 358
PTV V T P L VISIDHLP+LLPRE+SE FS L+PSL L APVWVRAKK
Sbjct: 300 HPTVEVKGVTTPPPLEVISIDHLPTLLPRESSEAFSEALIPSLLALKDVDNAPVWVRAKK 359
Query: 359 LFDRHCARV 367
L++ ++
Sbjct: 360 LYETMVQKL 368
>gb|EDU47954.1| saccharopine dehydrogenase [Pyrenophora tritici-repentis Pt-1C-BFP]
Length = 387
Score = 547 bits (1411), Expect = e-154, Method: Composition-based stats.
Identities = 212/382 (55%), Positives = 262/382 (68%), Gaps = 17/382 (4%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQ-----STFNINEYRQAG 55
MA TLH RAE KPLE R+ LTPTT KKL+ G+ + VE SP+ F +E+ + G
Sbjct: 1 MAFPTLHARAEAKPLEHRSCLTPTTAKKLLDAGYPVLVERSPKDPNYARIFKDDEFEEVG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A ++ G++KTAP+DRIIIGLKE+PE FPL H + FAHCYK Q GW+NVL RF +G
Sbjct: 61 ATLIEEGAYKTAPKDRIIIGLKELPEDK-FPLEHTFVHFAHCYKQQGGWENVLARFPRGG 119
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
GTLYDLEFL+++ GRRVAAFG++AGF GAAL ++ WA++ TH + E LP +
Sbjct: 120 GTLYDLEFLQDESGRRVAAFGYHAGFVGAALAIKTWAWQLTHPNGEPLPGLETFTEGRGY 179
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE L+ + +D KP+ L++GALGRCGSGA+DLL K+G P+ I KWD+
Sbjct: 180 YNNESELITQLKEDVAAGEKIAGHKPSSLVLGALGRCGSGAVDLLEKIGCPE--IKKWDL 237
Query: 229 KETS-RGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHN 287
ET R GP+ EI ++DIF+NCIYLSKPI PF N E L +PNRRL V DVS DTTNPHN
Sbjct: 238 AETKERDGPYPEIVESDIFVNCIYLSKPIPPFVNKESLKSPNRRLSVVCDVSCDTTNPHN 297
Query: 288 PIPIYTVATVFNKPTVLVPTTA-GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQ 346
PIPIY + T F+KPTV V GP+LSVISIDHLPS LPRE+SE FS+ LLPSL L
Sbjct: 298 PIPIYDINTTFDKPTVEVSVEGDGPRLSVISIDHLPSALPRESSEAFSNALLPSLMALKD 357
Query: 347 RKTAPVWVRAKKLFDRHCARVK 368
R T PVW A+KLF +
Sbjct: 358 RATTPVWQGAEKLFQEKVQTLP 379
>ref|XP_001803532.1| hypothetical protein SNOG_13323 [Phaeosphaeria nodorum SN15]
gb|EAT79207.1| hypothetical protein SNOG_13323 [Phaeosphaeria nodorum SN15]
Length = 387
Score = 546 bits (1409), Expect = e-154, Method: Composition-based stats.
Identities = 212/382 (55%), Positives = 261/382 (68%), Gaps = 17/382 (4%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQ-----STFNINEYRQAG 55
M+ TLH RAE KPLE R+ALTPTT KKL+ G+ + VE SP+ F E+ QAG
Sbjct: 1 MSFPTLHARAEAKPLEHRSALTPTTAKKLLDAGYPVLVERSPKDPNYARIFKDEEFEQAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A ++ G++KTAP+DRIIIGLKE+PE + FPL H + FAHCYK Q GW+ VL RF +G
Sbjct: 61 ATLIEEGAYKTAPKDRIIIGLKELPEDE-FPLEHTFVHFAHCYKQQGGWEKVLARFPRGG 119
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
GTLYDLEFL++ GRRVAAFG++AGF GAAL ++ WA++ TH + E LP V
Sbjct: 120 GTLYDLEFLQDTTGRRVAAFGYHAGFVGAALAIKTWAWQLTHPNGEPLPGVETFTDGRGY 179
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE L+ + +D KP+ L++GALGRCGSGA+DLL K+G P+ I KWD+
Sbjct: 180 YNNESELITQLKEDVAAGEKVAGHKPSSLVLGALGRCGSGAVDLLEKIGCPE--IKKWDL 237
Query: 229 KETS-RGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHN 287
ET R GP+ EI ++DIF+NCIYLSKPI PF N E L +P R+L V DVS DTTNPHN
Sbjct: 238 PETKERDGPYPEIIESDIFVNCIYLSKPIPPFVNKESLKSPKRKLSVVCDVSCDTTNPHN 297
Query: 288 PIPIYTVATVFNKPTVLVPTTA-GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQ 346
PIPIY + T F+KPTV V GP+LSVISIDHLPS LPRE+SE FS+ LLPSL L
Sbjct: 298 PIPIYDINTTFDKPTVGVDVEGDGPRLSVISIDHLPSALPRESSEAFSNALLPSLMALKD 357
Query: 347 RKTAPVWVRAKKLFDRHCARVK 368
R T PVW A+KLF +
Sbjct: 358 RATTPVWQGAEKLFQEKVQTLP 379
>ref|XP_001593244.1| saccharopine dehydrogenase [Sclerotinia sclerotiorum 1980]
gb|EDO03685.1| saccharopine dehydrogenase [Sclerotinia sclerotiorum 1980]
Length = 372
Score = 546 bits (1409), Expect = e-154, Method: Composition-based stats.
Identities = 217/370 (58%), Positives = 266/370 (71%), Gaps = 2/370 (0%)
Query: 1 MAAVTLHLRAET-KPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIV 59
M+ TLHLR+E K LE R+ALTPTT K LI G+ I VE SP+ F+ E+ + GA +V
Sbjct: 1 MSGTTLHLRSELGKALEHRSALTPTTAKALIDAGYTINVERSPERIFDDEEFEKVGATLV 60
Query: 60 PAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
P +W+ AP+D IIIGLKE+P D FPL H H+QFAHCYK Q GW VL RF +G GTL
Sbjct: 61 PEDTWRQAPKDHIIIGLKELPVED-FPLEHVHVQFAHCYKQQGGWDTVLSRFPRGGGTLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D+GRRVAAFG++AGFAGAAL + WA++ THS E P+VS YPNE L+ DV
Sbjct: 120 DLEFLTDDKGRRVAAFGYHAGFAGAALALETWAWQLTHSASEPFPSVSSYPNEDELIADV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
K + P VL+IGALGRCGSGA+DL + G+P N+LKWD+ ET++GGPF E
Sbjct: 180 KKAIAAGQEKTGKAPRVLVIGALGRCGSGAVDLCLRAGVPTENVLKWDMAETAKGGPFPE 239
Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
I ++DIFINCIYL I F +M+ L+ PNR+L V DVSADTTNP+NPIPIYTVAT F+
Sbjct: 240 IVESDIFINCIYLMSKIPNFVDMQSLDTPNRKLSVVCDVSADTTNPNNPIPIYTVATTFS 299
Query: 300 KPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
+PTV V P+LSVISIDHLPSLLPREASE FS DLLPSL L ++ PVW +A+KL
Sbjct: 300 EPTVPVEVKGDPRLSVISIDHLPSLLPREASEAFSKDLLPSLLTLKDWRSTPVWAKAEKL 359
Query: 360 FDRHCARVKR 369
F A + +
Sbjct: 360 FQEKVATLPK 369
>ref|XP_001819876.1| hypothetical protein [Aspergillus oryzae RIB40]
dbj|BAE57874.1| unnamed protein product [Aspergillus oryzae]
Length = 377
Score = 545 bits (1406), Expect = e-153, Method: Composition-based stats.
Identities = 207/378 (54%), Positives = 263/378 (69%), Gaps = 11/378 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQA-----G 55
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F+ +A G
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTAKALMDAGYEVTVERSTQRIFDGRLSIRAPLSRIG 60
Query: 56 AIIVPAGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKG 114
A +V GSW K AP+D ++GLKE+PE D FPL H HI FAHCYK Q GW+ VL R+ +G
Sbjct: 61 APLVEEGSWAKDAPKDAYVLGLKELPEDD-FPLEHVHITFAHCYKQQGGWEKVLRRWPRG 119
Query: 115 HGTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKA 174
GTL DLEFL ++ GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP PY N+
Sbjct: 120 GGTLLDLEFLTDEVGRRVAAFGWSAGYAGSALAVKNWAWQLTHPEGEPLPGEVPYANQDL 179
Query: 175 LVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRG 234
L + V + + R P +L+IGALGRCG+GA+ L VGIP+++I++WDI+ET +G
Sbjct: 180 LTQSVKESLEAGKKQSGRSPKILVIGALGRCGNGAVQLAKDVGIPESDIIRWDIEETKKG 239
Query: 235 GPFDEIPQADIFINCIYLSK-PIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYT 293
GPF EI ADIF+NCIYLS I PF N+E L+ PNRRL + DVSADTTNP+NPIP+Y
Sbjct: 240 GPFQEIIDADIFVNCIYLSSESIPPFVNVESLSTPNRRLSVICDVSADTTNPNNPIPVYD 299
Query: 294 VATVFNKPTVLV---PTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTA 350
+ T F+KPTV V T GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A
Sbjct: 300 ITTTFDKPTVPVTLPAGTQGPPLSVISIDHLPSLLPRESSEMFSQALLPSLLQLKNRKDA 359
Query: 351 PVWVRAKKLFDRHCARVK 368
VW +A+ LF + A +
Sbjct: 360 RVWTQAEDLFKQKVATLP 377
>ref|XP_001559795.1| saccharopine dehydrogenase [Botryotinia fuckeliana B05.10]
gb|EDN27084.1| saccharopine dehydrogenase [Botryotinia fuckeliana B05.10]
Length = 372
Score = 545 bits (1405), Expect = e-153, Method: Composition-based stats.
Identities = 215/371 (57%), Positives = 266/371 (71%), Gaps = 2/371 (0%)
Query: 1 MAAVTLHLRAET-KPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIV 59
M+ TLHLR+E K LE R+ALTPTT K LI G+ I VE SP+ F+ E+ + GA +V
Sbjct: 1 MSGTTLHLRSELGKALEHRSALTPTTAKALIDAGYTINVERSPERIFDDEEFEKVGATLV 60
Query: 60 PAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
P +W+ AP+D IIIGLKE+P + FPL H H+QFAHCYK Q GW VL RF +G GTL
Sbjct: 61 PENTWRQAPKDHIIIGLKELPVEE-FPLEHVHVQFAHCYKQQGGWDTVLSRFPRGGGTLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D+GRRVAAFG++AGFAGAAL + +WA++ TH E P+VS YPNE L+ DV
Sbjct: 120 DLEFLTDDRGRRVAAFGYHAGFAGAALALENWAWQLTHPASEPFPSVSSYPNEDELIVDV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
K + P VL+IGALGRCGSGA+DL + G+P N+LKWD+ ET++GGPF E
Sbjct: 180 KKAIAAGQEKTGKAPRVLVIGALGRCGSGAVDLCLRAGVPTENVLKWDMAETAKGGPFPE 239
Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
I ++DIFINCIYL I F +M+ L+ PNR+L V DVSADTTNP+NPIPIYTVAT F+
Sbjct: 240 IVESDIFINCIYLMSKIPNFVDMQSLDTPNRKLSVVCDVSADTTNPNNPIPIYTVATTFS 299
Query: 300 KPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
+PTV V P+LSVISIDHLPSLLPREASE FS DLLPSL L + PVW +A+KL
Sbjct: 300 EPTVPVEVKGEPRLSVISIDHLPSLLPREASEAFSKDLLPSLLSLKDWRNTPVWAKAEKL 359
Query: 360 FDRHCARVKRS 370
F A + ++
Sbjct: 360 FQEKVATLPKN 370
>ref|XP_964977.1| saccharopine dehydrogenase [Neurospora crassa OR74A]
sp|Q7SFX6|LYS1_NEUCR Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|EAA35741.1| saccharopine dehydrogenase [Neurospora crassa OR74A]
Length = 372
Score = 544 bits (1403), Expect = e-153, Method: Composition-based stats.
Identities = 224/372 (60%), Positives = 269/372 (72%), Gaps = 4/372 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MA LHLR+ETK LE R+ALTPTT +LI G+ + VE SP+ F+ E+ +AGA +VP
Sbjct: 1 MAPTVLHLRSETKHLEHRSALTPTTTAELIKAGYIVNVERSPERIFDDEEFEKAGATLVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
SW AP++ II+GLKE+ E FPL H H+QFAHCYK QAGW+NVL RF +G GTL D
Sbjct: 61 EHSWVDAPKEHIIVGLKEL-EEKDFPLKHVHVQFAHCYKQQAGWENVLARFPRGGGTLLD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL ++ GRRVAAFGF+AGFAGAAL + WA++ HS E P V YPNE AL+ DV
Sbjct: 120 LEFLVDEHGRRVAAFGFHAGFAGAALALEVWAWQLNHS--EPFPGVESYPNEDALIADVK 177
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K KE + R P V++IGA GRCGSGA+ L K GIPD NIL WD+ ET++GGPF EI
Sbjct: 178 KAVKEGVEAAGRLPRVIVIGARGRCGSGAVSALKKAGIPDENILDWDMAETAKGGPFKEI 237
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+DIF+NCIYL+ I F NME L P+R+LR V DVSADTT+P P+PIYTVAT F+K
Sbjct: 238 TDSDIFVNCIYLTSKIPNFVNMESLQVPDRQLRVVCDVSADTTSPFTPVPIYTVATTFDK 297
Query: 301 PTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
PTV V T+GP LSVISIDHLPSLLPREASE FSHDLLPSL L + +PVW RAK+L
Sbjct: 298 PTVPVDGLTSGPPLSVISIDHLPSLLPREASEAFSHDLLPSLLTLNDWQNSPVWARAKQL 357
Query: 360 FDRHCARVKRSS 371
FD A + S+
Sbjct: 358 FDEKVATLPESA 369
>ref|XP_001908761.1| unnamed protein product [Podospora anserina]
emb|CAP69434.1| unnamed protein product [Podospora anserina]
Length = 374
Score = 541 bits (1396), Expect = e-152, Method: Composition-based stats.
Identities = 219/372 (58%), Positives = 269/372 (72%), Gaps = 2/372 (0%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MA LHLR+ETKPLE R+ALTPTT LI G+ + VE SP+ F+ +E+ GA +VP
Sbjct: 1 MAPTVLHLRSETKPLEHRSALTPTTTAALIKAGYVVNVERSPERIFDDSEFEAVGATLVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW+ P++ II+GLKE+ E FPL H H+QFAHCYK QAGW+NVL RF +G GTL D
Sbjct: 61 EGSWEEVPKEHIIVGLKEL-EEKEFPLKHVHVQFAHCYKHQAGWENVLARFPRGGGTLLD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL +++GRRVAAFGF+AGFAGAAL + WA + TH P V+ YPNE AL+ +V
Sbjct: 120 LEFLVDERGRRVAAFGFHAGFAGAALALEVWAHQLTHPPSSPFPGVASYPNEDALITNVK 179
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K A R P V++IGALGRCGSGA+D L K G+P+ NILKWD+ ET++GGPF EI
Sbjct: 180 KALATGTAAAGRSPRVIVIGALGRCGSGAVDALRKAGVPEENILKWDMAETAKGGPFKEI 239
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+DIF+NCIYL+ I F N++ L P+R+L V DVSADTT+P P+PIYTVAT F+K
Sbjct: 240 TDSDIFVNCIYLTSKIPNFVNLDSLQVPDRKLSVVCDVSADTTSPFTPVPIYTVATTFDK 299
Query: 301 PTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
PTV V ++GP LSVISIDHLPSLLPREASE FSHDLLPSL L + +PVW RAKKL
Sbjct: 300 PTVPVEGLSSGPALSVISIDHLPSLLPREASEAFSHDLLPSLLTLNDWQNSPVWARAKKL 359
Query: 360 FDRHCARVKRSS 371
FD A + S+
Sbjct: 360 FDEKVATLPASA 371
>ref|XP_001220083.1| hypothetical protein CHGG_00862 [Chaetomium globosum CBS 148.51]
gb|EAQ92627.1| hypothetical protein CHGG_00862 [Chaetomium globosum CBS 148.51]
Length = 375
Score = 533 bits (1375), Expect = e-150, Method: Composition-based stats.
Identities = 215/375 (57%), Positives = 260/375 (69%), Gaps = 7/375 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MA LHLR+ETKPLE R+ALTPTT LI G+ + VE SP F+ E+ AGA +VP
Sbjct: 1 MAPTVLHLRSETKPLEHRSALTPTTTAALIKAGYTVNVERSPVRIFDDAEFEAAGATLVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
SW AP++ IIIGLKE+ E FPL H H+QFAHCYK Q GW+ VL RF +G GTL D
Sbjct: 61 EYSWVDAPKEHIIIGLKEL-EEKEFPLKHVHVQFAHCYKQQGGWETVLARFPRGGGTLLD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL ++ GRRVAAFG++AGFAGAAL + W+++ HS E P V YPNE ALV +V
Sbjct: 120 LEFLVDENGRRVAAFGYHAGFAGAALALEVWSWQLNHS--EPFPGVESYPNEDALVSNVK 177
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K + R P V++IGALGRCGSGA++ L K G+P+ NILKWD+ ET+ GGPF EI
Sbjct: 178 KALASGIEKAGRSPRVIVIGALGRCGSGAVEALRKAGVPEENILKWDMAETAGGGPFKEI 237
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSA---DTTNPHNPIPIYTVATV 297
+DIF+NCIYL+K I F N+E L P+R+L V DVSA DTT+P P+PIYTVAT
Sbjct: 238 TDSDIFVNCIYLTKKIPNFVNLESLQVPDRKLSVVCDVSAASQDTTSPFTPVPIYTVATT 297
Query: 298 FNKPTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRA 356
F++PTV V +GP LSVISIDHLPSLLPREASE FS DLLPSL L + PVW RA
Sbjct: 298 FDEPTVAVEGLQSGPALSVISIDHLPSLLPREASEAFSQDLLPSLLALNDWQNTPVWSRA 357
Query: 357 KKLFDRHCARVKRSS 371
KLF A + S+
Sbjct: 358 DKLFKEKVATLPASA 372
>gb|EEH34800.1| saccharopine dehydrogenase [Paracoccidioides brasiliensis Pb01]
Length = 384
Score = 533 bits (1374), Expect = e-150, Method: Composition-based stats.
Identities = 200/384 (52%), Positives = 257/384 (66%), Gaps = 15/384 (3%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAG 55
M+ VTLHLRAE K LE R+ALTP T + L+ G+ + VE SP + F E+ +AG
Sbjct: 1 MSPVTLHLRAEDKILEHRSALTPATTRALVDAGYIVRVERSPTSALRKRIFPDAEFEEAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +VP GSW AP D II+GLKE+ ET FPL H H+ FAHCYK+Q GW+ L R+ +G+
Sbjct: 61 ATLVPEGSWVDAPLDSIILGLKELDETKDFPLRHAHVTFAHCYKNQGGWEKSLGRWSRGN 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
G LYDLEFL++D GRR+AAFG++AGFAGAAL ++ WA++ H D LP V
Sbjct: 121 GVLYDLEFLQDDNGRRIAAFGYHAGFAGAALALKTWAWQLEHPDGTPLPGVEQFTDGRGY 180
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE ++ + D R+P VLIIGALGRCG GA+D K G +IL+WD+
Sbjct: 181 YLNEAEMIGQIRNDVARGEKIATRRPRVLIIGALGRCGKGAVDACVKAG--CEDILRWDM 238
Query: 229 KETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNP 288
ET++GGPF EI ++DIF+NCIYLS+ IAPF +ME L +P+RRL + DVS DTTNP+NP
Sbjct: 239 AETAKGGPFQEIVESDIFVNCIYLSEKIAPFVDMESLKSPDRRLSVICDVSCDTTNPNNP 298
Query: 289 IPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRK 348
IPIY + T F KPTV +P + P LSVISIDHLPSLLP E+S FS DLLP ++ + R
Sbjct: 299 IPIYNINTTFGKPTVALPL-SNPPLSVISIDHLPSLLPAESSNAFSADLLPYMKEIKHRD 357
Query: 349 TAPVWVRAKKLFDRHCARVKRSSR 372
+ PVW RA+KLF + +
Sbjct: 358 SNPVWQRAEKLFRDKVKALPEELQ 381
>ref|XP_363433.1| hypothetical protein MGG_01359 [Magnaporthe grisea 70-15]
gb|EDK04946.1| hypothetical protein MGG_01359 [Magnaporthe grisea 70-15]
Length = 365
Score = 528 bits (1361), Expect = e-148, Method: Composition-based stats.
Identities = 214/369 (57%), Positives = 263/369 (71%), Gaps = 5/369 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M+++ LHLR+ETKPLE R+ALTPTT K LI G+ + VE SP F+ E+ GA +VP
Sbjct: 1 MSSI-LHLRSETKPLEHRSALTPTTTKALIEAGYTVNVERSPVRIFDDAEFEAVGATLVP 59
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW+ P+D I+IGLKE+ E FPL H HIQFAHCYK+Q GW VL R+ G G L D
Sbjct: 60 EGSWEQIPKDHIVIGLKEL-EEKDFPLKHTHIQFAHCYKNQGGWDKVLRRYHDGEGMLLD 118
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
+EFLE D GRRVAAFG++AGFAGAAL +++WA++ T+S E LP+V PNE ALV D+
Sbjct: 119 IEFLEKD-GRRVAAFGYWAGFAGAALALQNWAWQLTNS-GEPLPSVESRPNEAALVGDIK 176
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
+ R P V++IGALGRCG GA+D+ K GIPD NILKWD++ET+ GGPF EI
Sbjct: 177 EALAGGKEKAGRLPRVIVIGALGRCGRGAVDMCKKAGIPDENILKWDMEETAPGGPFKEI 236
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
++DIF+NCIYL+K I PF ME LN P R+L + D SADTTNP NP+P+YTVAT F+K
Sbjct: 237 VESDIFVNCIYLNKQIPPFVTMESLNTPERKLSVINDCSADTTNPFNPVPVYTVATTFDK 296
Query: 301 PTVLVP-TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
PTV V + GP LSVISIDHLPSLLPREASE FS+DLLP L L K+ PVW A+KL
Sbjct: 297 PTVPVDGLSHGPPLSVISIDHLPSLLPREASESFSNDLLPYLLKLKDWKSDPVWAGAEKL 356
Query: 360 FDRHCARVK 368
F +
Sbjct: 357 FHEKVKTLP 365
>ref|XP_001745712.1| predicted protein [Monosiga brevicollis MX1]
gb|EDQ89683.1| predicted protein [Monosiga brevicollis MX1]
Length = 499
Score = 509 bits (1313), Expect = e-142, Method: Composition-based stats.
Identities = 177/368 (48%), Positives = 236/368 (64%), Gaps = 7/368 (1%)
Query: 5 TLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP----QSTFNINEYRQAGAIIVP 60
L LR+E K E R ALTP K+L+ +G+ I VE SP + + ++Y G +
Sbjct: 132 HLWLRSEVKANEHRTALTPEACKELLGEGYTITVERSPEASTKRIYEDSDYEAVGCQLAE 191
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
+ SW +AP+D II+GLKE+PE + PL H H+ F HCYK+Q GW+++L RF G+G+L D
Sbjct: 192 SQSWPSAPKDAIIVGLKELPEDGS-PLEHTHLYFGHCYKNQGGWKDLLKRFHAGNGSLLD 250
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
+EFL NDQGRRVAAFG+ AGFAG+ + W ++ D + A+S YPNE L+K
Sbjct: 251 MEFLTNDQGRRVAAFGYMAGFAGSFSALDVWCHRKLEGD-KPYGALSAYPNEDELLKYSR 309
Query: 181 KDYKEALATG-ARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ A A R P VL+IGALGRCG+GA D + GIP+AN+L+WD+ ET GGPF+E
Sbjct: 310 ARIEAAAAKNDGRLPRVLVIGALGRCGNGACDFATRAGIPEANVLRWDMAETKVGGPFNE 369
Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
+ DIF+NCIYLS+PI PF L +R L V DVS DT+NPHNPIP +T F+
Sbjct: 370 LLDVDIFVNCIYLSQPIPPFITEAMLEKEDRALSVVCDVSCDTSNPHNPIPFANKSTTFD 429
Query: 300 KPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
+PT V G + VI+IDHLP+LLP+E+S+ + HDLLPS+ L + PVW RA KL
Sbjct: 430 EPTYQVKPKVGGPVDVITIDHLPTLLPKESSDRYCHDLLPSIRELKNMDSNPVWQRAIKL 489
Query: 360 FDRHCARV 367
F+ A
Sbjct: 490 FEEKKALA 497
>emb|CAX65448.1| putative saccharopine dehydrogenase (NAD+,L-lysine-forming)
[Gibberella fujikuroi]
Length = 390
Score = 505 bits (1302), Expect = e-141, Method: Composition-based stats.
Identities = 193/385 (50%), Positives = 241/385 (62%), Gaps = 19/385 (4%)
Query: 4 VTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAGAII 58
+ LRAE KPLE R+ +P +K L+ G+ I VE S + F +EY AGA +
Sbjct: 5 PHILLRAEEKPLEHRS-FSPAIIKTLVDAGYPISVERSSTDPKFKRIFEDSEYEAAGARL 63
Query: 59 VPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTL 118
V G W A II+GLKE+P D FPL ++HI FAHCYK+Q GW+ VL R+ +G L
Sbjct: 64 VDTGVWPNAEPGTIILGLKELPSED-FPLKNDHITFAHCYKNQGGWEQVLGRWARGGSRL 122
Query: 119 YDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP-------YPN 171
YDLEFL ++QGRRV+AFG++AGFAGAALG++ A + LP+V Y N
Sbjct: 123 YDLEFLVDEQGRRVSAFGYHAGFAGAALGIKTLAHQ-LQGSSSKLPSVETFTDGRGYYLN 181
Query: 172 EKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKET 231
E LV + +D +A RKPT L++GALGRCG GA+DL K G+PD NI +WD+ ET
Sbjct: 182 EDELVNQIREDLAKAEKALGRKPTALVLGALGRCGKGAVDLFLKAGMPDDNITRWDLNET 241
Query: 232 S-RGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIP 290
R GP++EI +AD+F+N IYLSKPI PF N E L R L V+DVS DTTNPHNPIP
Sbjct: 242 KDRDGPYEEIAKADVFLNAIYLSKPIPPFINQELLAKQGRNLAVVIDVSCDTTNPHNPIP 301
Query: 291 IYTVATVFNKPTVLVPTTAGP---KLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQR 347
IY++ T F PTV V LSVISIDHLPS+LPREASE FS L SL L R
Sbjct: 302 IYSINTTFEDPTVPVEIKDDQNNLPLSVISIDHLPSMLPREASEAFSEGLKESLLTLKDR 361
Query: 348 KTAPVWVRAKKLFDRHCARVKRSSR 372
+T+ VW A+KLF A + R
Sbjct: 362 ETSRVWTDAEKLFHEKVALLPEELR 386
>ref|XP_001544099.1| saccharopine dehydrogenase [Ajellomyces capsulatus NAm1]
gb|EDN03281.1| saccharopine dehydrogenase [Ajellomyces capsulatus NAm1]
Length = 376
Score = 505 bits (1301), Expect = e-141, Method: Composition-based stats.
Identities = 194/384 (50%), Positives = 253/384 (65%), Gaps = 23/384 (5%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAG 55
MA VTLHLR E K LE R+ALTP T + L+ G+ + +E SP + F E+ +AG
Sbjct: 1 MAPVTLHLRTEDKILEHRSALTPQTTRLLVDAGYIVNIERSPTSALRKRIFPDAEFEKAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +VP GSW AP D II+GLKE+ ET FPL H H+ FAHCYK Q GW+ L R+ +G+
Sbjct: 61 ATLVPEGSWVDAPLDHIILGLKELDETKDFPLRHAHVTFAHCYKGQGGWEKALGRWSRGN 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
G LYDLEFL++D GRR+AAFG++AGFAGAAL ++ WA++ H D LP+V
Sbjct: 121 GVLYDLEFLQDDIGRRIAAFGYHAGFAGAALALKTWAWQLQHPD-TPLPSVDHFTDGRGY 179
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NEK +V + +D KP VL+IGALGRCG GA+D K G ++L+WD+
Sbjct: 180 YLNEKEMVDQIREDVIRGEKIAGHKPRVLVIGALGRCGRGAVDACVKAG--CEDVLRWDM 237
Query: 229 KETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNP 288
ET++GGPF EI ++DIF+NCIYL++ I PF +ME L +PNR+L V DVS DTTNP+NP
Sbjct: 238 AETAKGGPFQEIVESDIFVNCIYLNEKIPPFVDMESLKSPNRKLSVVCDVSCDTTNPNNP 297
Query: 289 IPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRK 348
I F+KPTV +P + P LSVISIDHLPSLLP E+S+ FS DLLP + + R
Sbjct: 298 I-------TFDKPTVPLPL-SNPPLSVISIDHLPSLLPAESSDAFSTDLLPCMMEIKNRA 349
Query: 349 TAPVWVRAKKLFDRHCARVKRSSR 372
+ PVW RA+KLF + + +
Sbjct: 350 SHPVWQRAEKLFREKVKTLPEALQ 373
>ref|YP_612102.1| alanine dehydrogenase/PNT-like [Silicibacter sp. TM1040]
gb|ABF62840.1| saccharopine dehydrogenase (NAD+, L-lysine-forming) [Silicibacter
sp. TM1040]
Length = 350
Score = 503 bits (1297), Expect = e-141, Method: Composition-based stats.
Identities = 155/363 (42%), Positives = 215/363 (59%), Gaps = 14/363 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE + E R LTP K L+ G ++ VE+S + Y AG I P
Sbjct: 1 MTHLWVRAEQRLNEDRVGLTPAGAKALLEAGIRVTVEESSSRAIPLQGYIDAGCEIAPEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
+W APRD II GLKE+P+ T PL H HI F H +K Q + +L RF +G GTLYDLE
Sbjct: 61 AWPDAPRDAIIFGLKELPDDGT-PLPHRHIMFGHAFKGQHSGKELLRRFREGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L + GRRVAAFG++AG+AGAA+ ++ WA +Q E V Y N+ AL+ D+ ++
Sbjct: 120 YLVDPSGRRVAAFGYWAGYAGAAVTLKAWAAQQR---GETCGPVGVYKNKDALLADLGRE 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
ATGA +P ++IGALGR G+GA DL +G + KWD+ ET+ GGPF EI
Sbjct: 177 LD---ATGADRPKAIVIGALGRVGTGAADLCEAMG---VAVTKWDMNETASGGPFPEILD 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
D+F+NCI+ ++P P ++ R L + DV+ D + +NP+P+Y+ AT ++ P
Sbjct: 231 HDLFLNCIF-ARPGTPVFVPKEALTAARNLTAIGDVACDPDSDYNPVPVYSRATTWDAPV 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V V P L V++ID+LPS+LP E+SE ++ LL SL L A VW RAK +FD
Sbjct: 290 VRVAND--PVLDVMAIDNLPSMLPAESSEDYADQLLASLLTLSDLD-AGVWGRAKAVFDE 346
Query: 363 HCA 365
H A
Sbjct: 347 HVA 349
>ref|ZP_01753990.1| saccharopine dehydrogenase, putative [Roseobacter sp. SK209-2-6]
gb|EBA17471.1| saccharopine dehydrogenase, putative [Roseobacter sp. SK209-2-6]
Length = 352
Score = 503 bits (1296), Expect = e-140, Method: Composition-based stats.
Identities = 149/364 (40%), Positives = 204/364 (56%), Gaps = 14/364 (3%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M L +RAE +P E R LTP K L+ G ++ VE S + Y AG +
Sbjct: 1 MTMTHLWVRAEQRPNEDRVGLTPEGAKALLDAGLRVTVEKSSVRAIPMQGYIDAGCEVAA 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
SW AP D II GLKE+PE T PL H HI F H +K Q + +L RF G GTLYD
Sbjct: 61 ENSWPKAPADAIIFGLKELPEDGT-PLPHRHIMFGHAFKGQHSGKALLDRFQAGGGTLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LE+L + GRRVAAFG++AG+AGAA+ ++ W +Q E V Y + AL+ D+
Sbjct: 120 LEYLVEENGRRVAAFGYWAGYAGAAVTLKTWMAQQR---GELCGPVGVYSGKDALLADLG 176
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
+ A A KP ++IGALGR G+GA DL +G + KWD+ ETS GGPF EI
Sbjct: 177 AELD---ALDAEKPKAIVIGALGRVGTGAADLCEAMG---VAVTKWDMAETSSGGPFPEI 230
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+ D+F+NCI+ ++P P + R L + DV+ D + +NP+P+Y AT ++
Sbjct: 231 LEHDLFLNCIF-ARPGTPVFVPQDALGTARNLSAIGDVACDPDSDYNPVPVYDRATTWDA 289
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
P + V P L V++ID+LPS+LP E+S ++ LLPSL L K+ VW RA+ F
Sbjct: 290 PALRV--AEDPVLDVMAIDNLPSMLPVESSIDYAEQLLPSLLTLTDLKSG-VWGRAEATF 346
Query: 361 DRHC 364
Sbjct: 347 REFV 350
>ref|XP_391101.1| hypothetical protein FG10925.1 [Gibberella zeae PH-1]
Length = 383
Score = 492 bits (1269), Expect = e-137, Method: Composition-based stats.
Identities = 192/389 (49%), Positives = 245/389 (62%), Gaps = 27/389 (6%)
Query: 1 MAA-VTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQA 54
M+ + LRAE KPLE R+ +P+ +K L+ G+ + VE S + F +EY A
Sbjct: 1 MSQYPHILLRAEEKPLEHRS-FSPSIIKTLVDAGYPVSVERSSTDPKFKRIFEDSEYEAA 59
Query: 55 GAIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKG 114
GA +V G+W A +I+GLKE+PE D FPL ++HI +Q GW+ VL RF +G
Sbjct: 60 GARLVNEGTWPNAEAGTLILGLKEIPEED-FPLKNDHI-------NQGGWEKVLGRFPQG 111
Query: 115 HGTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------ 168
LYDLEFL ++QGRRV+AFGF+AGFAGAALG++ A + LP+V
Sbjct: 112 SSVLYDLEFLVDEQGRRVSAFGFHAGFAGAALGIKTLAHQ-LQDPSSKLPSVETFTDGRG 170
Query: 169 -YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWD 227
Y NE+ LV + +D +A + RKPT L++GALGRCG GA+DL K G+PD NI +WD
Sbjct: 171 YYLNEEELVNQIREDLAKAEKSLGRKPTALVLGALGRCGKGAVDLFLKAGMPDENITRWD 230
Query: 228 IKETS-RGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPH 286
+ ET R GP++EI QAD+F+N IYLSKPI PF N E L R L V+DVS DTTNPH
Sbjct: 231 LNETKDRDGPYEEIAQADVFLNAIYLSKPIPPFINEELLAKSGRNLAVVIDVSCDTTNPH 290
Query: 287 NPIPIYTVATVFNKPTVLVPTTAGP---KLSVISIDHLPSLLPREASEFFSHDLLPSLEL 343
NPIPIY++ T F +PTV V LSVISIDHLPS+LPREASE FS L SL
Sbjct: 291 NPIPIYSINTTFEEPTVPVEIKNDQNSLPLSVISIDHLPSMLPREASEAFSEGLKESLLT 350
Query: 344 LPQRKTAPVWVRAKKLFDRHCARVKRSSR 372
L RKT+ VW A+KLF+ A + S R
Sbjct: 351 LKDRKTSRVWADAEKLFNEKVALLPESLR 379
>ref|ZP_01034544.1| saccharopine dehydrogenase, putative [Roseovarius sp. 217]
gb|EAQ27225.1| saccharopine dehydrogenase, putative [Roseovarius sp. 217]
Length = 351
Score = 492 bits (1268), Expect = e-137, Method: Composition-based stats.
Identities = 153/362 (42%), Positives = 204/362 (56%), Gaps = 14/362 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE +P E R LTP +LI KG ++ VE+S I YR AG I
Sbjct: 1 MTHLWVRAEQRPNEERVGLTPEGAAQLITKGIRVTVEESHNRAIPIESYRAAGCEIATEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW +AP + II GLKE+PE DT PL H HI F H +K Q + +L RF GTLYDLE
Sbjct: 61 SWPSAPTEAIIFGLKELPEDDT-PLPHRHIMFGHAFKGQHAGRRLLQRFKARGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L ++ GRRVAAFG++AG+AGAA+ + W +Q P V YP AL+ D+
Sbjct: 120 YLVDETGRRVAAFGYWAGYAGAAVSLMAWTAQQ---GGAICPPVDTYPGRDALLADLGAQ 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
ATGA +P ++IGALGR G+GA DL + D + +WD+ ET+ GGPF EI
Sbjct: 177 LD---ATGASRPRAIVIGALGRVGTGAADLCEAM---DVTVTRWDMAETASGGPFPEILA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
DIF+NCI+ F L+ P R+L + DV+ D + +NP+P+Y AT + P
Sbjct: 231 HDIFLNCIFARPGTPVFVPKSALDQP-RQLTVIGDVACDPDSDYNPVPVYDAATSWAAPV 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V P L V++ID+LPSLLP E+S ++ LL SL L VW RA + F
Sbjct: 290 LRVHD--APPLDVMAIDNLPSLLPVESSRDYAGQLLASLLTLDTLDQG-VWGRAAETFHT 346
Query: 363 HC 364
H
Sbjct: 347 HM 348
>ref|ZP_01901689.1| saccharopine dehydrogenase, putative [Roseobacter sp. AzwK-3b]
gb|EDM73387.1| saccharopine dehydrogenase, putative [Roseobacter sp. AzwK-3b]
Length = 353
Score = 490 bits (1263), Expect = e-137, Method: Composition-based stats.
Identities = 160/366 (43%), Positives = 213/366 (58%), Gaps = 14/366 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L LRAE + E R LTP LIA+G + VEDS I YR AG I P
Sbjct: 1 MTHLWLRAEQRANEDRTGLTPEGAAALIARGLTVTVEDSRTRILPIEAYRAAGCAIAPEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
+W APRD II GLKE+P+ T PL H HI F H +K Q + +L RF G GTLYDLE
Sbjct: 61 AWPDAPRDAIIFGLKELPDDGT-PLPHRHIMFGHAFKGQHAGRRLLERFKAGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L + +GRRVAAFG++AG+AGAA+ + WA ++ P VS + ++ AL+ D+
Sbjct: 120 YLVDPEGRRVAAFGYWAGYAGAAISLMAWAAQRQ---GGLCPPVSAFADKDALLADLGAR 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
ATG ++P+ ++IGALGR G+GA DL +GI +WD+ ET+ GGPF EI
Sbjct: 177 LD---ATGTKRPSAIVIGALGRVGTGAADLCTAMGITP---TRWDMAETAHGGPFPEILA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
DIF+NCI+ F E L +R L + DV+ D + +NP+P+Y AT ++ P
Sbjct: 231 HDIFLNCIFARPGTPVFVPREALTQ-DRHLTVIGDVACDPDSDYNPVPVYASATTWDAPV 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V T P L V++ID+LPSLLP E+S ++ LLPSL L A VW RAK FD+
Sbjct: 290 TRVHDT--PPLDVMAIDNLPSLLPLESSLDYAAQLLPSLLTLDALD-AGVWGRAKATFDQ 346
Query: 363 HCARVK 368
H V+
Sbjct: 347 HMKEVR 352
>ref|ZP_01057918.1| saccharopine dehydrogenase, putative [Roseobacter sp. MED193]
gb|EAQ44058.1| saccharopine dehydrogenase, putative [Roseobacter sp. MED193]
Length = 350
Score = 489 bits (1260), Expect = e-136, Method: Composition-based stats.
Identities = 155/358 (43%), Positives = 209/358 (58%), Gaps = 14/358 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE +P E R LTP K L++ G K+ VE+S + Y AG I P
Sbjct: 1 MTHLWVRAEQRPNEDRVGLTPEGAKALLSGGIKVTVEESSVRAIPLQGYIDAGCEIAPEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW TAP D II GLKE+PE T PL H HI F H +K Q + +L RF G GTLYDLE
Sbjct: 61 SWPTAPADAIIFGLKELPEDGT-PLPHRHIMFGHAFKGQHSGKALLDRFAAGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L ++ GRRVAAFG++AG+AGAA+ ++ W +Q E V YP + AL+ ++ +
Sbjct: 120 YLVDEAGRRVAAFGYWAGYAGAAVTLKSWCAQQR---GEICGPVGVYPGKDALLTELGAE 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
K A A PT ++IGA+GR G+GA DL +G + KWD+ ET+ GGPF EI Q
Sbjct: 177 LK---AVPADVPTAIVIGAMGRVGTGAADLCEAMG---VTVTKWDMAETASGGPFPEILQ 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
D+F+NCI+ F E L R+L + DV+ D + +NP+PIY AT + P
Sbjct: 231 HDLFLNCIFARPGTPVFVPAEALTAA-RKLTAIGDVACDPDSDYNPVPIYAEATSWEAPA 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
+ V P + V++ID+LPS+LP E+SE ++ LLPSL L KT VW RA+ F
Sbjct: 290 LRVAND--PVMDVMAIDNLPSMLPVESSEDYAAQLLPSLLTLTDLKTG-VWGRAETTF 344
>ref|YP_168503.1| saccharopine dehydrogenase, putative [Silicibacter pomeroyi DSS-3]
gb|AAV96534.1| saccharopine dehydrogenase, putative [Silicibacter pomeroyi DSS-3]
Length = 350
Score = 484 bits (1246), Expect = e-135, Method: Composition-based stats.
Identities = 156/362 (43%), Positives = 208/362 (57%), Gaps = 14/362 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE +P E R LTP LIA G ++ VE+S ++ YR AG I P
Sbjct: 1 MTHLWVRAEQRPNEERVGLTPEGAAALIAAGLRVTVEESSVRAIPLDGYRDAGCQIAPEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW AP D II GLKE+PE T PL H HI F H +K Q + +L RF G GTLYDLE
Sbjct: 61 SWPDAPGDAIIFGLKELPEDGT-PLPHRHIMFGHAFKGQHSGRRLLERFKAGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L ++ GRRVAAFG++AG+AGAA+ ++ WA +Q V YP + L + +
Sbjct: 120 YLVDENGRRVAAFGYWAGYAGAAVTLKAWAAQQQ---GGICGPVGVYPGKDTLNAALAAE 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
ATGA +P ++IGALGR G+GA DL +G + KWD+ ET+ GGPF EI
Sbjct: 177 LD---ATGAPRPRAIVIGALGRVGTGAADLCTAMG---VEVTKWDMAETASGGPFPEILA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
DIF+NCI+ F E L+ P R L + DV+ D + +NP+P+Y AT ++ P
Sbjct: 231 HDIFLNCIFARPGTPVFVPREALSAP-RALTAIGDVACDPDSDYNPVPVYDRATSWDAPV 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V P L V++ID+LPS+LP E+SE ++ LLPSL L A VW RA+ F
Sbjct: 290 LRV--AEAPVLDVMAIDNLPSMLPVESSEDYAAQLLPSLLTLTDLD-AGVWGRARATFLG 346
Query: 363 HC 364
H
Sbjct: 347 HV 348
>gb|EEH50065.1| saccharopine dehydrogenase [Paracoccidioides brasiliensis Pb18]
Length = 377
Score = 484 bits (1246), Expect = e-135, Method: Composition-based stats.
Identities = 184/388 (47%), Positives = 241/388 (62%), Gaps = 30/388 (7%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAG 55
M+ VTLHLRAE K LE R+ALTP T + L+ G+ + VE SP + F E+ +AG
Sbjct: 1 MSPVTLHLRAEDKILEHRSALTPATTRALVDAGYIVKVERSPTSALRKRIFPDAEFEEAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +VP GSW AP D II+GLKE+ ET FPL H H+ FAHCYK+Q GW+ L R+ +G+
Sbjct: 61 ATLVPEGSWVDAPLDSIILGLKELDETKDFPLRHAHVTFAHCYKNQGGWEKSLGRWSRGN 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGF----AGAALGVRDWAFKQTHSDDEDLPAVSP--- 168
G LYDLEFL+ + G + G+ AGAAL ++ W ++ H D LP V
Sbjct: 121 GVLYDLEFLQ----VSLIIIGQFGGYHAGFAGAALALKTWVWQLEHPDGTPLPGVEQFTD 176
Query: 169 ----YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANIL 224
Y NE ++ + D R+P +L+IGALGRCG GA+D K G +IL
Sbjct: 177 GRGYYLNEAEMISQIRNDVARGEKIATRRPRILVIGALGRCGKGAVDACVKAG--CEDIL 234
Query: 225 KWDIKETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTN 284
+WD+ ET++GGPF EI ++D+F+NCIYLS+ IAPF +ME L +PNRRL + DVS DTTN
Sbjct: 235 RWDMAETAKGGPFQEIVESDVFVNCIYLSEKIAPFIDMESLKSPNRRLSVICDVSCDTTN 294
Query: 285 PHNPIPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELL 344
P+NPI F KPTV +P + P LSVISIDHLPSLLP E+S FS DLLP ++ +
Sbjct: 295 PNNPI-------TFGKPTVALPL-SNPPLSVISIDHLPSLLPAESSNAFSADLLPYMKEI 346
Query: 345 PQRKTAPVWVRAKKLFDRHCARVKRSSR 372
R + PVW RA+KLF + +
Sbjct: 347 RHRDSNPVWQRAEKLFRDKVKALPEELQ 374
>ref|XP_001828899.1| hypothetical protein CC1G_03693 [Coprinopsis cinerea okayama7#130]
gb|EAU92906.1| hypothetical protein CC1G_03693 [Coprinopsis cinerea okayama7#130]
Length = 369
Score = 482 bits (1241), Expect = e-134, Method: Composition-based stats.
Identities = 203/363 (55%), Positives = 236/363 (65%), Gaps = 11/363 (3%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M+ TL LR E K E RAALTPTT KKLI GF I+VE Q F+ +EY AG +V
Sbjct: 1 MSKPTLWLRCEKKEFERRAALTPTTAKKLIEAGFDIFVEKDEQRIFDDSEYEAAGCKLVE 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
+W +AP+D IIGLKE+P +D PL H HIQFAHCYK Q GW VL RF KG GTLYD
Sbjct: 61 NNTWASAPKDVPIIGLKELPVSDE-PLPHTHIQFAHCYKKQGGWSQVLARFYKGGGTLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL ++ GRRVAAFGF AG A +DL ++PYPNE A+V DV
Sbjct: 120 LEFLNDENGRRVAAFGF---HAGFAGAAAGALAVAARRQGKDLGLLTPYPNEAAMVDDVK 176
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K + L+IGALGRCG GA+DL K+G+ + +ILKWD+ ET++GGPF EI
Sbjct: 177 KSLG----GSGKGLKALVIGALGRCGRGAVDLFRKIGLEENDILKWDMAETAKGGPFPEI 232
Query: 241 PQADIFINCIYLSKPIAPFTNMEK--LNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
DIF+NCIYLS I F E +RRL VVDVS DTTNP+NPIPIY + T F
Sbjct: 233 LDVDIFVNCIYLSSQIPSFITKETAIAAGKDRRLSVVVDVSCDTTNPYNPIPIYNINTTF 292
Query: 299 NKPTVLVPT-TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAK 357
+KPTV V P LSVISIDHLP+LLPREASE FS DLLPSL PQR TA VWV A+
Sbjct: 293 DKPTVAVDVGAENPPLSVISIDHLPTLLPREASEQFSGDLLPSLLEFPQRSTARVWVEAE 352
Query: 358 KLF 360
KLF
Sbjct: 353 KLF 355
>ref|ZP_01002428.1| saccharopine dehydrogenase (NAD+, L-lysine forming) [Loktanella
vestfoldensis SKA53]
gb|EAQ07678.1| saccharopine dehydrogenase (NAD+, L-lysine forming) [Loktanella
vestfoldensis SKA53]
Length = 354
Score = 480 bits (1237), Expect = e-134, Method: Composition-based stats.
Identities = 152/367 (41%), Positives = 209/367 (56%), Gaps = 14/367 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
++ L +RAE++P E R LTP +LIA GF++ VEDS Q I +Y AG P
Sbjct: 2 SIHLWVRAESRPHEERTGLTPQGAARLIAAGFRVTVEDSRQRIIPIADYAAAGCATAPEF 61
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
W AP +I GLKE+P+ T PL H HI F H YK Q Q +L RF G G L DLE
Sbjct: 62 GWPDAPEGAVIFGLKELPDDGT-PLRHRHIMFGHAYKGQPAGQVLLGRFRAGGGRLLDLE 120
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L +D GRRVAAFG++AG+AGAA+ + W +Q + V YP+ L+ D+
Sbjct: 121 YLMDDDGRRVAAFGYWAGYAGAAVALLCWMAQQR---GQVAGPVRAYPSAAHLLGDLQSG 177
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
+A G ++PT LIIGALGR G+GA DL +G+P + KWD+ ET+ GGPF ++
Sbjct: 178 L---VALGTKRPTALIIGALGRVGAGAADLCGAMGVP---VTKWDMAETAHGGPFPQVLA 231
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
DIF+NCI L++P P RRL + D++ D + +PI +Y T ++ P
Sbjct: 232 HDIFLNCI-LARPGTPVFVPSSAKVAARRLTVIGDIACDPDSDFSPIKVYDRTTTWDAPA 290
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V P L V +ID+LPS++P E+SE F+ LLP L L R + VW A+ FDR
Sbjct: 291 LRVHD--APVLDVTAIDNLPSMMPTESSEDFAAQLLPHLATL-DRMDSGVWAGAQAWFDR 347
Query: 363 HCARVKR 369
+ R
Sbjct: 348 AMDQTGR 354
>ref|ZP_01881158.1| saccharopine dehydrogenase, putative [Roseovarius sp. TM1035]
gb|EDM30677.1| saccharopine dehydrogenase, putative [Roseovarius sp. TM1035]
Length = 351
Score = 479 bits (1234), Expect = e-133, Method: Composition-based stats.
Identities = 154/365 (42%), Positives = 212/365 (58%), Gaps = 14/365 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE +P E R LTP +LIAKG ++ VE+S I+ YR AG I P
Sbjct: 1 MTHLWVRAEQRPNEERVGLTPEGAAQLIAKGIRVTVEESQNRAIPIDGYRAAGCEIAPEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
+W +AP+D II GLKE+PE T PL H HI F H +K Q + +L RF G GTLYDLE
Sbjct: 61 AWPSAPQDAIIFGLKELPEDGT-PLPHRHIMFGHAFKGQHAGRRLLQRFQAGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L + GRRVAAFG++AG+AGAA+ + WA +Q P V YP AL+ D+
Sbjct: 120 YLVDVTGRRVAAFGYWAGYAGAAVSLMAWAAQQ---GGGLCPTVDTYPGRDALLADLGAR 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
+ A+GA +P ++IGALGR G+GA DL + +P + +WD+ ET+ GGPF EI
Sbjct: 177 LE---ASGATRPRAIVIGALGRVGTGAADLCEAMDVP---VTRWDMAETASGGPFPEILT 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
DIF+NCI+ ++P P + R L + DV+ D + +NP+P+Y AT + P
Sbjct: 231 HDIFLNCIF-ARPGTPVFVPKSALAAPRHLTVIGDVACDPDSDYNPVPVYDAATTWAAPV 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V P L V++ID+LPSLLP E+S+ ++ LL SL L VW RA + F
Sbjct: 290 LRVHDV--PPLDVMAIDNLPSLLPVESSQDYAGQLLTSLLTLDTPDQG-VWGRAAETFHT 346
Query: 363 HCARV 367
H +
Sbjct: 347 HMKAL 351
>ref|YP_001044623.1| alanine dehydrogenase/PNT domain protein [Rhodobacter sphaeroides
ATCC 17029]
gb|ABN77851.1| saccharopine dehydrogenase (NAD+, L-lysine-forming) [Rhodobacter
sphaeroides ATCC 17029]
Length = 351
Score = 478 bits (1232), Expect = e-133, Method: Composition-based stats.
Identities = 154/362 (42%), Positives = 207/362 (57%), Gaps = 14/362 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE +P E R LTP LIA+G ++ VE S +I Y AG I P
Sbjct: 1 MTHLWVRAEQRPNEERVGLTPEGAAALIARGLRVTVEASRTRALSIEGYAAAGCAIAPEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW TAP D I+ GLKE+PE T PL H HI F H YK Q + +L RF G GTLYDLE
Sbjct: 61 SWPTAPADAIVFGLKELPEDGT-PLRHRHILFGHAYKGQPAGRILLERFRAGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
L ++ GRRVAAFG++AG+AGAA+ ++ WA + V+ +P + L+ D+ +
Sbjct: 120 SLVDESGRRVAAFGYWAGYAGAAVALKCWAAQAR---GGICDPVTTWPGREGLLADLGAE 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
A GAR+P L+IGA GR G+GA DL +G+ + +WD++ET+ GGPF E+
Sbjct: 177 LTSA---GARQPRALVIGARGRVGTGAADLCESMGLA---VTRWDMEETAHGGPFPEVLA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
+IF+NCI F E L P R LR + D++ D T+ +P+ +Y T + P
Sbjct: 231 HEIFLNCILARPGCPVFVPAEALEAP-RALRVIGDIACDPTSDFSPVKVYNRTTSWTAPA 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V P L V++ID+LPSLLP E+S ++ LLPSL L R VW RAK FDR
Sbjct: 290 LRVHDD--PMLDVMAIDNLPSLLPVESSVDYAAQLLPSLLTL-DRIEEGVWGRAKAEFDR 346
Query: 363 HC 364
H
Sbjct: 347 HM 348
>ref|ZP_02150991.1| saccharopine dehydrogenase, putative [Phaeobacter gallaeciensis
2.10]
gb|EDQ07479.1| saccharopine dehydrogenase, putative [Phaeobacter gallaeciensis
2.10]
Length = 350
Score = 478 bits (1232), Expect = e-133, Method: Composition-based stats.
Identities = 148/362 (40%), Positives = 205/362 (56%), Gaps = 14/362 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE +P E R LTP K L+A G K+ VE+S + Y AG I
Sbjct: 1 MTHLWVRAEQRPNEERVGLTPEGAKALLAAGIKVTVEESSVRAIPLQGYIDAGCDITAEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
+W AP D II GLKE+PE T PL H HI F H +K Q + +L RF G GTLYDLE
Sbjct: 61 TWPDAPTDAIIFGLKELPEDGT-PLPHRHIMFGHAFKGQHSGKALLERFKAGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L ++ GRRVAAFG++AG+AGAA+ ++ WA +Q E V Y ++ AL+ D+ +
Sbjct: 120 YLVDETGRRVAAFGYWAGYAGAAVTLKTWAAQQR---SELCGPVGVYESKDALLTDLGAE 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
A +PT ++IGALGR G+GA DL +GI + KWD+ ET+ GGPF +I
Sbjct: 177 LD---ALKVERPTAMVIGALGRVGTGAADLCEAMGIK---VTKWDMAETASGGPFPQILA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
D+F+NCI+ F E L +R+L + DV+ D + +NP+P+Y AT + P
Sbjct: 231 HDLFLNCIFARPGTPVFVPREALEQ-DRQLSAIGDVACDPDSDYNPVPVYDRATTWASPA 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V P L V++ID+LPS+LP E+SE ++ L S L + VW RA+ F
Sbjct: 290 LRV--AEHPVLDVMAIDNLPSMLPVESSEDYAAQ-LLSSLLTLTDLQSGVWGRAETTFKD 346
Query: 363 HC 364
H
Sbjct: 347 HL 348
>ref|ZP_01751929.1| saccharopine dehydrogenase, putative [Roseobacter sp. CCS2]
gb|EBA11220.1| saccharopine dehydrogenase, putative [Roseobacter sp. CCS2]
Length = 349
Score = 478 bits (1231), Expect = e-133, Method: Composition-based stats.
Identities = 148/360 (41%), Positives = 205/360 (56%), Gaps = 14/360 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
+ +R+E + E R LTP KL+A G+++ VE+S Q + I +Y AG + P
Sbjct: 1 MTHIWVRSEARAHEERVGLTPQGAAKLLAAGYQVTVEESTQRSLPIADYAAAGCDVTPEF 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW AP + II GLKE+PE T PL H HI F H YK Q + +L RF G GTLYDLE
Sbjct: 61 SWVDAPDNAIIFGLKELPEDGT-PLRHRHIMFGHAYKGQPSGKVLLNRFKAGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L + GRRVAAFG++AG+AGAA+ + W +Q + + V YP+ L+ ++ +D
Sbjct: 120 YLTEEDGRRVAAFGYWAGYAGAAVSLMCWMAQQ---NGKVAGPVKAYPSANHLLMELQQD 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
+A G +PT LIIGALGR G+GA DL +G KWD+ ET+ GGPF E+
Sbjct: 177 L---MALGTDRPTALIIGALGRVGTGAADLCQAMG---VGTTKWDMAETASGGPFPEVLA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
+IF+NCI L++P P R L + D++ D + +PI +Y T + P
Sbjct: 231 HNIFLNCI-LARPGTPVFVPASAKVAPRALSVIGDIACDPDSDFSPIKVYDRTTTWGAPA 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V P L V +ID+LPSLLP E+SE F+ LLP L L + VW RA+ FD+
Sbjct: 290 LRVHDR--PVLDVTAIDNLPSLLPAESSEDFAEQLLPHLMTL-SDISKGVWGRAQGWFDQ 346
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
emb|CAA54551.1| saccharopine dehydrogenase (NAD+, L-lysine ... 457 e-127
ref|NP_012300.1| Saccharopine dehydrogenase (NAD+, L-lysine... 456 e-127
pdb|2QRJ|A Chain A, Crystal Structure Of Sulfate-Bound Sacc... 456 e-126
ref|XP_446267.1| unnamed protein product [Candida glabrata]... 456 e-126
pdb|2Q99|A Chain A, Crystal Structure Of Saccharopine Dehyd... 455 e-126
ref|XP_001387327.1| Saccharopine dehydrogenase [NAD+, L-lys... 455 e-126
ref|XP_457987.1| hypothetical protein DEHA0C07832g [Debaryo... 445 e-123
sp|P43065|LYS1_CANAL Saccharopine dehydrogenase [NAD+, L-ly... 444 e-123
ref|XP_001643683.1| hypothetical protein Kpol_1057p13 [Vand... 442 e-122
ref|XP_001213891.1| hypothetical protein ATEG_04713 [Asperg... 442 e-122
ref|XP_454310.1| unnamed protein product [Kluyveromyces lac... 441 e-122
ref|XP_001399884.1| hypothetical protein An02g07500 [Asperg... 441 e-122
ref|XP_660477.1| hypothetical protein AN2873.2 [Aspergillus... 441 e-122
ref|XP_001523078.1| saccharopine dehydrogenase [Lodderomyce... 440 e-122
ref|XP_754450.1| saccharopine dehydrogenase Lys1 [Aspergill... 438 e-121
ref|XP_001263295.1| saccharopine dehydrogenase Lys1, putati... 438 e-121
ref|XP_500931.1| YlLYS5 [Yarrowia lipolytica] >gi|729965|sp... 438 e-121
ref|XP_001271170.1| saccharopine dehydrogenase Lys1, putati... 428 e-118
sp|Q870G1|LYS1_EMENI Saccharopine dehydrogenase [NAD+, L-ly... 425 e-117
ref|XP_001482345.1| hypothetical protein PGUG_05365 [Pichia... 424 e-117
ref|XP_001246345.1| hypothetical protein CIMG_00116 [Coccid... 424 e-117
ref|NP_983569.1| ACR167Cp [Ashbya gossypii ATCC 10895] >gi|... 424 e-117
ref|XP_964977.1| saccharopine dehydrogenase [Neurospora cra... 421 e-116
ref|XP_001908761.1| unnamed protein product [Podospora anse... 420 e-116
ref|XP_001559795.1| saccharopine dehydrogenase [Botryotinia... 419 e-115
ref|XP_001819876.1| hypothetical protein [Aspergillus oryza... 414 e-114
ref|XP_001593244.1| saccharopine dehydrogenase [Sclerotinia... 414 e-114
ref|XP_001803532.1| hypothetical protein SNOG_13323 [Phaeos... 413 e-113
ref|NP_592972.1| saccharopine dehydrogenase [NAD+, L-lysine... 412 e-113
gb|EEH34800.1| saccharopine dehydrogenase [Paracoccidioides... 412 e-113
ref|XP_363433.1| hypothetical protein MGG_01359 [Magnaporth... 411 e-113
gb|EDU47954.1| saccharopine dehydrogenase [Pyrenophora trit... 409 e-112
ref|XP_001220083.1| hypothetical protein CHGG_00862 [Chaeto... 407 e-112
ref|XP_001745712.1| predicted protein [Monosiga brevicollis... 403 e-110
emb|CAX65448.1| putative saccharopine dehydrogenase (NAD+,L... 389 e-106
ref|XP_001544099.1| saccharopine dehydrogenase [Ajellomyces... 385 e-105
ref|XP_001873276.1| predicted protein [Laccaria bicolor S23... 377 e-103
ref|YP_612102.1| alanine dehydrogenase/PNT-like [Silicibact... 375 e-102
ref|XP_391101.1| hypothetical protein FG10925.1 [Gibberella... 371 e-101
ref|XP_570078.1| saccharopine dehydrogenase (NAD+, L-lysine... 371 e-101
ref|XP_001828899.1| hypothetical protein CC1G_03693 [Coprin... 371 e-101
gb|EEH50065.1| saccharopine dehydrogenase [Paracoccidioides... 370 e-100
ref|ZP_01753990.1| saccharopine dehydrogenase, putative [Ro... 369 e-100
ref|ZP_00630414.1| Alanine dehydrogenase/PNT, C-terminal:Al... 366 1e-99
ref|ZP_01034544.1| saccharopine dehydrogenase, putative [Ro... 365 2e-99
ref|ZP_01901689.1| saccharopine dehydrogenase, putative [Ro... 362 3e-98
ref|YP_168503.1| saccharopine dehydrogenase, putative [Sili... 359 2e-97
ref|ZP_01442866.1| saccharopine dehydrogenase, putative [Ro... 359 3e-97
ref|YP_001044623.1| alanine dehydrogenase/PNT domain protei... 357 7e-97
ref|YP_681080.1| saccharopine dehydrogenase, putative [Rose... 357 7e-97
ref|ZP_01751929.1| saccharopine dehydrogenase, putative [Ro... 356 1e-96
ref|YP_354173.1| saccharopine dehydrogenase (NAD+, L-lysine... 356 2e-96
ref|ZP_01881158.1| saccharopine dehydrogenase, putative [Ro... 354 6e-96
ref|YP_001169133.1| Saccharopine dehydrogenase (NAD(+), L-l... 354 6e-96
ref|ZP_02143453.1| saccharopine dehydrogenase, putative [Ro... 353 1e-95
ref|ZP_01057918.1| saccharopine dehydrogenase, putative [Ro... 352 2e-95
ref|ZP_02150991.1| saccharopine dehydrogenase, putative [Ph... 352 2e-95
ref|ZP_00948710.1| saccharopine dehydrogenase (NAD+, L-lysi... 352 2e-95
ref|ZP_02146801.1| saccharopine dehydrogenase, putative [Ph... 350 1e-94
ref|ZP_01002428.1| saccharopine dehydrogenase (NAD+, L-lysi... 349 2e-94
ref|ZP_02152850.1| saccharopine dehydrogenase, putative [Oc... 349 2e-94
ref|YP_001366419.1| alanine dehydrogenase [Shewanella balti... 348 4e-94
ref|YP_963387.1| alanine dehydrogenase [Shewanella sp. W3-1... 347 6e-94
ref|ZP_01446787.1| saccharopine dehydrogenase (NAD+, L-lysi... 347 1e-93
ref|ZP_00954164.1| saccharopine dehydrogenase (NAD+, L-lysi... 347 1e-93
ref|ZP_02914793.1| alanine dehydrogenase [Geobacillus sp. W... 347 1e-93
ref|YP_869684.1| alanine dehydrogenase [Shewanella sp. ANA-... 347 1e-93
ref|YP_734091.1| alanine dehydrogenase [Shewanella sp. MR-4... 346 1e-93
ref|YP_001050520.1| alanine dehydrogenase [Shewanella balti... 345 4e-93
ref|YP_001126767.1| Alanine dehydrogenase [Geobacillus ther... 343 2e-92
ref|XP_760415.1| hypothetical protein UM04268.1 [Ustilago m... 342 2e-92
ref|ZP_02424229.1| hypothetical protein ALIPUT_00344 [Alist... 342 2e-92
ref|YP_001554753.1| alanine dehydrogenase [Shewanella balti... 342 2e-92
ref|ZP_01740684.1| saccharopine dehydrogenase, putative [Rh... 342 3e-92
ref|ZP_01074124.1| alanine dehydrogenase [Marinomonas sp. M... 342 3e-92
ref|YP_001376512.1| alanine dehydrogenase [Bacillus cereus ... 341 5e-92
ref|ZP_01736276.1| alanine dehydrogenase [Marinobacter sp. ... 341 6e-92
ref|NP_646469.1| alanine dehydrogenase [Staphylococcus aure... 340 9e-92
ref|YP_927645.1| alanine dehydrogenase [Shewanella amazonen... 340 1e-91
ref|YP_041174.1| alanine dehydrogenase 1 [Staphylococcus au... 340 1e-91
ref|YP_359521.1| alanine dehydrogenase [Carboxydothermus hy... 340 1e-91
ref|YP_148605.1| alanine dehydrogenase [Geobacillus kaustop... 340 2e-91
gb|EEJ79897.1| L-alanine dehydrogenase [Kangiella koreensis... 339 2e-91
ref|NP_372233.1| alanine dehydrogenase [Staphylococcus aure... 339 2e-91
ref|ZP_03987947.1| alanine dehydrogenase [Staphylococcus au... 339 2e-91
ref|NP_374819.1| alanine dehydrogenase [Staphylococcus aure... 339 2e-91
ref|YP_417038.1| alanine dehydrogenase [Staphylococcus aure... 339 2e-91
ref|YP_001647239.1| alanine dehydrogenase [Bacillus weihens... 339 2e-91
ref|ZP_01052096.1| putative alanine dehydrogenase [Tenaciba... 339 3e-91
ref|YP_001094151.1| alanine dehydrogenase [Shewanella loihi... 339 3e-91
ref|NP_847074.1| alanine dehydrogenase [Bacillus anthracis ... 339 3e-91
ref|ZP_01062209.1| putative alanine dehydrogenase [Flavobac... 338 4e-91
ref|YP_001301040.1| alanine dehydrogenase [Bacteroides vulg... 338 5e-91
ref|ZP_00740055.1| Alanine dehydrogenase [Bacillus thuringi... 338 5e-91
ref|ZP_03900458.1| L-alanine dehydrogenase [Dyadobacter fer... 338 5e-91
ref|ZP_00517716.1| Alanine dehydrogenase and pyridine nucle... 338 5e-91
ref|ZP_01723571.1| alanine dehydrogenase [Bacillus sp. B149... 338 5e-91
ref|ZP_02262771.1| alanine dehydrogenase [Bacillus cereus A... 337 7e-91
ref|YP_001502090.1| alanine dehydrogenase [Shewanella peale... 337 8e-91
ref|YP_001917832.1| L-alanine dehydrogenase [Natranaerobius... 337 9e-91
ref|YP_001760857.1| alanine dehydrogenase [Shewanella woody... 337 1e-90
ref|YP_001674437.1| alanine dehydrogenase [Shewanella halif... 336 1e-90
ref|XP_001634023.1| predicted protein [Nematostella vectens... 336 1e-90
ref|ZP_01215557.1| alanine dehydrogenase [Psychromonas sp. ... 336 2e-90
ref|YP_098760.1| alanine dehydrogenase [Bacteroides fragili... 335 2e-90
ref|ZP_02585793.1| alanine dehydrogenase (L-alanine dehydro... 335 2e-90
ref|ZP_01043459.1| Alanine dehydrogenase [Idiomarina baltic... 335 3e-90
ref|ZP_02330643.1| alanine dehydrogenase [Paenibacillus lar... 335 3e-90
ref|ZP_02522526.1| alanine dehydrogenase (L-alanine dehydro... 335 4e-90
ref|ZP_00959701.1| saccharopine dehydrogenase, putative [Ro... 335 4e-90
dbj|BAA77513.1| alanine dehydrogenase [Enterobacter aerogenes] 335 4e-90
ref|YP_944887.1| alanine dehydrogenase [Psychromonas ingrah... 335 5e-90
ref|YP_001155448.1| alanine dehydrogenase [Polynucleobacter... 334 6e-90
ref|NP_827683.1| L-alanine dehydrogenase [Streptomyces aver... 334 6e-90
ref|YP_750481.1| alanine dehydrogenase [Shewanella frigidim... 334 6e-90
gb|AAC23578.1| alanine dehydrogenase [Shewanella sp. Ac10] 334 6e-90
ref|ZP_01235013.1| putative alanine dehydrogenase [Vibrio a... 334 7e-90
ref|ZP_01891777.1| putative alanine dehydrogenase [unidenti... 334 7e-90
ref|YP_253131.1| alanine dehydrogenase [Staphylococcus haem... 334 7e-90
ref|YP_550034.1| alanine dehydrogenase [Polaromonas sp. JS6... 334 8e-90
gb|AAL87460.1| alanine dehydrogenase [Shewanella sp. PA-43] 334 8e-90
ref|YP_001327051.1| alanine dehydrogenase [Sinorhizobium me... 334 9e-90
ref|ZP_01159834.1| putative alanine dehydrogenase [Photobac... 334 1e-89
ref|YP_001643400.1| alanine dehydrogenase [Bacillus weihens... 333 1e-89
ref|ZP_01120364.1| putative alanine dehydrogenase [Robigini... 333 1e-89
ref|ZP_02072824.1| hypothetical protein BACUNI_04278 [Bacte... 333 1e-89
ref|YP_340233.1| Alanine dehydrogenase [Pseudoalteromonas h... 333 1e-89
ref|ZP_02434435.1| hypothetical protein BACSTE_00661 [Bacte... 333 1e-89
ref|YP_001192379.1| alanine dehydrogenase [Flavobacterium j... 333 2e-89
ref|ZP_01164841.1| alanine dehydrogenase [Oceanospirillum s... 332 2e-89
ref|ZP_02579479.1| alanine dehydrogenase (L-alanine dehydro... 332 2e-89
ref|YP_562748.1| alanine dehydrogenase [Shewanella denitrif... 332 2e-89
ref|ZP_02147727.1| alanine dehydrogenase [Phaeobacter galla... 332 2e-89
ref|ZP_01219314.1| hypothetical saccharopine dehydrogenase ... 332 3e-89
ref|ZP_01754550.1| alanine dehydrogenase [Roseobacter sp. S... 332 3e-89
ref|NP_385730.1| PROBABLE ALANINE DEHYDROGENASE OXIDOREDUCT... 332 3e-89
ref|ZP_02144676.1| alanine dehydrogenase [Phaeobacter galla... 332 3e-89
ref|YP_001127463.1| Alanine dehydrogenase [Geobacillus ther... 332 3e-89
ref|YP_002826017.1| alanine dehydrogenase [Rhizobium sp. NG... 332 3e-89
ref|ZP_01958087.1| alanine dehydrogenase [Vibrio cholerae M... 332 3e-89
ref|YP_001488077.1| alanine dehydrogenase [Bacillus pumilus... 332 4e-89
ref|YP_130399.1| putative alanine dehydrogenase [Photobacte... 332 4e-89
ref|ZP_01731833.1| Alanine dehydrogenase and pyridine nucle... 332 4e-89
ref|NP_231539.1| alanine dehydrogenase [Vibrio cholerae O1 ... 331 5e-89
ref|YP_301147.1| alanine dehydrogenase [Staphylococcus sapr... 331 6e-89
ref|ZP_01049900.1| putative alanine dehydrogenase [Cellulop... 331 6e-89
ref|ZP_01223017.1| putative alanine dehydrogenase [Photobac... 331 6e-89
ref|ZP_01816459.1| alanine dehydrogenase [Vibrionales bacte... 331 7e-89
ref|ZP_01899015.1| alanine dehydrogenase [Moritella sp. PE3... 331 7e-89
ref|ZP_01746654.1| saccharopine dehydrogenase, putative [Sa... 330 7e-89
ref|YP_001444991.1| alanine dehydrogenase [Vibrio harveyi A... 330 8e-89
ref|YP_001473862.1| alanine dehydrogenase [Shewanella sedim... 330 8e-89
sp|P17557|DHA_BACST Alanine dehydrogenase >gi|142455|gb|AAA... 330 1e-88
ref|ZP_01067027.1| Alanine dehydrogenase [Vibrio sp. MED222... 330 1e-88
ref|NP_797482.1| alanine dehydrogenase [Vibrio parahaemolyt... 330 1e-88
ref|ZP_01261877.1| alanine dehydrogenase [Vibrio alginolyti... 330 1e-88
ref|NP_764939.1| alanine dehydrogenase [Staphylococcus epid... 330 1e-88
ref|ZP_01991915.1| alanine dehydrogenase [Vibrio parahaemol... 330 1e-88
ref|YP_001861152.1| alanine dehydrogenase [Burkholderia phy... 330 2e-88
ref|ZP_01202668.1| alanine dehydrogenase [Flavobacteria bac... 329 2e-88
ref|ZP_01118752.1| putative alanine dehydrogenase [Polariba... 329 2e-88
ref|ZP_02067293.1| hypothetical protein BACOVA_04297 [Bacte... 329 2e-88
ref|ZP_01308570.1| alanine dehydrogenase [Oceanobacter sp. ... 329 2e-88
ref|YP_662032.1| alanine dehydrogenase [Pseudoalteromonas a... 329 2e-88
ref|ZP_01612926.1| Alanine dehydrogenase [Alteromonadales b... 329 2e-88
ref|ZP_01946735.1| alanine dehydrogenase [Coxiella burnetii... 329 2e-88
ref|YP_923679.1| alanine dehydrogenase [Nocardioides sp. JS... 329 2e-88
ref|ZP_01908911.1| alanine dehydrogenase [Plesiocystis paci... 329 2e-88
ref|YP_001217438.1| alanine dehydrogenase [Vibrio cholerae ... 329 2e-88
ref|YP_001394062.1| Ald [Clostridium kluyveri DSM 555] >gi|... 329 3e-88
ref|NP_761756.1| Alanine dehydrogenase [Vibrio vulnificus C... 329 3e-88
ref|NP_391071.1| L-alanine dehydrogenase [Bacillus subtilis... 329 3e-88
ref|YP_132774.1| hypothetical saccharopine dehydrogenase [P... 329 3e-88
ref|YP_300065.1| Alanine dehydrogenase and pyridine nucleot... 328 4e-88
ref|YP_886996.1| alanine dehydrogenase [Mycobacterium smegm... 328 4e-88
gb|ABR57171.1| alanine dehydrogenase [Staphylococcus xylosus] 328 4e-88
ref|ZP_01697384.1| alanine dehydrogenase [Bacillus coagulan... 328 4e-88
ref|NP_621858.1| Alanine dehydrogenase [Thermoanaerobacter ... 328 5e-88
ref|NP_840123.1| alanine dehydrogenase [Nitrosomonas europa... 328 5e-88
ref|ZP_02195873.1| alanine dehydrogenase [Vibrio campbellii... 328 5e-88
ref|ZP_00992904.1| Alanine dehydrogenase [Vibrio splendidus... 328 6e-88
ref|YP_001424576.1| alanine dehydrogenase [Coxiella burneti... 327 6e-88
gb|AAC23579.1| alanine dehydrogenase [Vibrio proteolyticus] 327 8e-88
ref|ZP_01255407.1| putative alanine dehydrogenase [Psychrof... 327 1e-87
ref|ZP_01444021.1| alanine dehydrogenase [Roseovarius sp. H... 327 1e-87
ref|ZP_00952239.1| alanine dehydrogenase [Oceanicaulis alex... 327 1e-87
ref|YP_854776.1| alanine dehydrogenase [Aeromonas hydrophil... 326 2e-87
ref|ZP_02883918.1| alanine dehydrogenase [Burkholderia gram... 326 2e-87
ref|NP_810467.1| alanine dehydrogenase [Bacteroides thetaio... 326 2e-87
ref|YP_155059.1| Alanine dehydrogenase [Idiomarina loihiens... 326 2e-87
ref|ZP_02941837.1| alanine dehydrogenase [Cyanothece sp. PC... 325 2e-87
ref|ZP_01058751.1| alanine dehydrogenase [Roseobacter sp. M... 325 2e-87
ref|YP_143482.1| alanine dehydrogenase [Thermus thermophilu... 325 3e-87
ref|NP_626044.1| L-alanine dehydrogenase [Streptomyces coel... 325 3e-87
ref|NP_820115.1| alanine dehydrogenase [Coxiella burnetii R... 325 3e-87
ref|YP_611857.1| alanine dehydrogenase [Silicibacter sp. TM... 325 3e-87
ref|ZP_00959435.1| alanine dehydrogenase [Roseovarius nubin... 325 3e-87
ref|YP_002774420.1| alanine dehydrogenase [Brevibacillus br... 325 4e-87
gb|AAP44334.1| alanine dehydrogenase [Thermus caldophilus] 325 4e-87
ref|ZP_01901606.1| hypothetical protein RAZWK3B_03750 [Rose... 325 4e-87
ref|YP_005739.1| alanine dehydrogenase [Thermus thermophilu... 324 6e-87
ref|YP_001211208.1| alanine dehydrogenase [Pelotomaculum th... 324 7e-87
ref|YP_001661762.1| alanine dehydrogenase [Thermoanaerobact... 324 7e-87
ref|YP_001143837.1| alanine dehydrogenase [Aeromonas salmon... 323 9e-87
ref|ZP_02184200.1| stage V sporulation protein N (L-alanine... 323 1e-86
ref|YP_001666058.1| alanine dehydrogenase [Thermoanaerobact... 323 1e-86
ref|ZP_02159718.1| alanine dehydrogenase [Shewanella benthi... 323 1e-86
ref|XP_711455.1| saccharopine dehydrogenase [Candida albica... 323 1e-86
ref|ZP_01134782.1| Alanine dehydrogenase [Pseudoalteromonas... 323 1e-86
ref|ZP_02137052.1| alanine dehydrogenase [Vibrio fischeri M... 323 1e-86
ref|XP_001324625.1| Alanine dehydrogenase 2, putative [Tric... 323 1e-86
ref|YP_756289.1| alanine dehydrogenase [Maricaulis maris MC... 323 2e-86
ref|YP_949946.1| alanine dehydrogenase [Arthrobacter auresc... 323 2e-86
ref|YP_204286.1| alanine dehydrogenase [Vibrio fischeri ES1... 322 2e-86
emb|CAM75354.1| Alanine dehydrogenase and pyridine nucleoti... 322 2e-86
ref|YP_001827236.1| putative L-alanine dehydrogenase [Strep... 322 2e-86
ref|ZP_01870578.1| alanine dehydrogenase [Vibrio shilonii A... 322 3e-86
ref|ZP_01439206.1| alanine dehydrogenase [Fulvimarina pelag... 322 3e-86
ref|ZP_01863314.1| Alanine dehydrogenase and pyridine nucle... 322 3e-86
ref|ZP_01895406.1| alanine dehydrogenase [Marinobacter algi... 322 3e-86
ref|XP_001732779.1| hypothetical protein MGL_0554 [Malassez... 322 3e-86
ref|ZP_01721568.1| putative alanine dehydrogenase [Algoriph... 322 3e-86
ref|YP_001070365.1| alanine dehydrogenase [Mycobacterium sp... 322 4e-86
ref|YP_474564.1| alanine dehydrogenase [Synechococcus sp. J... 322 4e-86
gb|ABC26869.1| AldA [Bradyrhizobium sp. UPM1167] 322 4e-86
ref|ZP_02913777.1| alanine dehydrogenase [Geobacillus sp. W... 321 4e-86
ref|YP_673989.1| alanine dehydrogenase [Mesorhizobium sp. B... 321 4e-86
ref|XP_684074.2| PREDICTED: similar to lysine ketoglutarate... 321 5e-86
ref|ZP_01158968.1| putative alanine dehydrogenase [Photobac... 321 5e-86
ref|YP_953175.1| alanine dehydrogenase [Mycobacterium vanba... 321 6e-86
ref|YP_459264.1| Alanine dehydrogenase and pyridine nucleot... 321 7e-86
ref|ZP_01101833.1| alanine dehydrogenase [gamma proteobacte... 320 9e-86
ref|YP_002764322.1| alanine dehydrogenase [Rhodococcus eryt... 320 9e-86
ref|YP_411850.1| alanine dehydrogenase [Nitrosospira multif... 320 1e-85
ref|YP_001168635.1| alanine dehydrogenase [Rhodobacter spha... 320 1e-85
ref|NP_901692.1| alanine dehydrogenase [Chromobacterium vio... 320 1e-85
ref|YP_001422460.1| Ald [Bacillus amyloliquefaciens FZB42] ... 320 1e-85
ref|YP_639268.1| alanine dehydrogenase [Mycobacterium sp. M... 320 2e-85
ref|ZP_02931419.1| alanine dehydrogenase [Verrucomicrobium ... 320 2e-85
ref|ZP_01154744.1| saccharopine dehydrogenase (NAD+, L-lysi... 319 2e-85
ref|YP_517218.1| hypothetical protein DSY0985 [Desulfitobac... 319 2e-85
ref|YP_722774.1| alanine dehydrogenase [Trichodesmium eryth... 319 2e-85
ref|ZP_02078507.1| hypothetical protein EUBDOL_02329 [Eubac... 319 2e-85
ref|YP_604242.1| alanine dehydrogenase [Deinococcus geother... 319 2e-85
ref|ZP_01114638.1| alanine dehydrogenase [Reinekea sp. MED2... 319 2e-85
ref|YP_165491.1| alanine dehydrogenase [Silicibacter pomero... 319 2e-85
ref|NP_988633.1| alanine dehydrogenase [Methanococcus marip... 319 2e-85
ref|YP_001801454.1| alanine dehydrogenase [Cyanothece sp. A... 319 2e-85
ref|YP_511957.1| Saccharopine dehydrogenase (NAD+, L-lysine... 319 2e-85
ref|YP_001323343.1| alanine dehydrogenase [Methanococcus va... 319 2e-85
ref|ZP_02323668.1| alanine dehydrogenase [Anaeromyxobacter ... 319 2e-85
ref|YP_001850232.1| secreted L-alanine dehydrogenase Ald (4... 319 2e-85
gb|EEK00373.1| L-alanine dehydrogenase [Tsukamurella paurom... 319 2e-85
ref|YP_001135275.1| alanine dehydrogenase [Mycobacterium gi... 319 2e-85
ref|YP_525283.1| alanine dehydrogenase [Rhodoferax ferrired... 318 3e-85
ref|ZP_02140129.1| alanine dehydrogenase [Roseobacter litor... 318 3e-85
ref|YP_465316.1| L-alanine dehydrogenase [Anaeromyxobacter ... 318 3e-85
ref|YP_080482.1| L-alanine dehydrogenase [Bacillus lichenif... 318 4e-85
ref|YP_882850.1| alanine dehydrogenase [Mycobacterium avium... 318 4e-85
ref|YP_906040.1| secreted L-alanine dehydrogenase Ald (40 k... 318 5e-85
ref|YP_001815332.1| alanine dehydrogenase [Exiguobacterium ... 318 5e-85
ref|YP_746463.1| alanine dehydrogenase [Nitrosomonas eutrop... 318 5e-85
ref|YP_001096594.1| alanine dehydrogenase [Methanococcus ma... 318 5e-85
sp|P17556|DHA_BACSH Alanine dehydrogenase >gi|142453|gb|AAA... 318 6e-85
ref|ZP_01688551.1| alanine dehydrogenase [Microscilla marin... 318 6e-85
ref|ZP_01233072.1| putative alanine dehydrogenase [Vibrio a... 317 6e-85
ref|YP_001108475.1| putative L-alanine dehydrogenase [Sacch... 317 7e-85
ref|YP_266230.1| alanine dehydrogenase [Candidatus Pelagiba... 317 7e-85
ref|NP_085655.1| alanine dehydrogenase [Mesorhizobium loti ... 317 8e-85
ref|YP_461225.1| alanine dehydrogenase [Syntrophus aciditro... 317 9e-85
gb|EEJ95596.1| L-alanine dehydrogenase [Thermomonospora cur... 317 9e-85
ref|ZP_03863415.1| L-alanine dehydrogenase [Kribbella flavi... 317 1e-84
ref|YP_477594.1| alanine dehydrogenase [Synechococcus sp. J... 317 1e-84
ref|NP_961822.1| Ald [Mycobacterium avium subsp. paratuberc... 317 1e-84
ref|YP_285355.1| Alanine dehydrogenase and pyridine nucleot... 317 1e-84
ref|ZP_02190089.1| hypothetical protein BAL199_30152 [alpha... 317 1e-84
ref|NP_244046.1| alanine dehydrogenase [Bacillus halodurans... 317 1e-84
ref|ZP_02428013.1| hypothetical protein CLORAM_01403 [Clost... 316 2e-84
ref|ZP_04009917.1| alanine dehydrogenase [Lactobacillus sal... 316 2e-84
ref|YP_149301.1| stage V sporulation protein N (L-alanine d... 316 2e-84
ref|YP_001114195.1| alanine dehydrogenase [Desulfotomaculum... 316 2e-84
ref|ZP_02175777.1| alanine dehydrogenase [Anaeromyxobacter ... 316 2e-84
ref|NP_768378.1| alanine dehydrogenase [Bradyrhizobium japo... 316 2e-84
ref|YP_001329977.1| alanine dehydrogenase [Methanococcus ma... 316 2e-84
ref|NP_302068.1| L-alanine dehydrogenase [Mycobacterium lep... 315 2e-84
Sequences not found previously or not previously below threshold:
ref|YP_001373857.1| alanine dehydrogenase [Bacillus cereus ... 337 7e-91
ref|ZP_02581070.1| Alanine dehydrogenase [Bacillus cereus B... 337 8e-91
ref|ZP_02522062.1| alanine dehydrogenase [Bacillus cereus A... 337 8e-91
ref|NP_834329.1| Alanine dehydrogenase [Bacillus cereus ATC... 335 2e-90
ref|ZP_01859623.1| alanine dehydrogenase [Bacillus sp. SG-1... 335 2e-90
ref|NP_830409.1| Alanine dehydrogenase [Bacillus cereus ATC... 335 3e-90
ref|YP_082111.1| alanine dehydrogenase (L-alanine dehydroge... 335 4e-90
ref|NP_693109.1| alanine dehydrogenase [Oceanobacillus ihey... 331 4e-89
ref|YP_001412833.1| alanine dehydrogenase [Parvibaculum lav... 327 9e-88
ref|NP_243195.1| alanine dehydrogenase (stage V sporulation... 323 1e-86
ref|YP_081348.1| alanine dehydrogenase (stage V sporulation... 322 3e-86
ref|YP_826544.1| alanine dehydrogenase [Solibacter usitatus... 322 3e-86
ref|YP_123314.1| hypothetical protein lpp0986 [Legionella p... 319 2e-85
ref|YP_129373.1| putative alanine dehydrogenase [Photobacte... 317 8e-85
ref|YP_001528954.1| alanine dehydrogenase [Desulfococcus ol... 316 2e-84
>emb|CAA54551.1| saccharopine dehydrogenase (NAD+, L-lysine forming) [Saccharomyces
cerevisiae]
Length = 373
Score = 457 bits (1177), Expect = e-127, Method: Composition-based stats.
Identities = 372/373 (99%), Positives = 372/373 (99%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTT GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 301 PTVLVPTTVGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 361 DRHCARVKRSSRL 373
>ref|NP_012300.1| Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the
conversion of saccharopine to L-lysine, which is the
final step in the lysine biosynthesis pathway; Lys1p
[Saccharomyces cerevisiae]
sp|P38998|LYS1_YEAST Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
emb|CAA86194.1| lys1 [Saccharomyces cerevisiae]
gb|EDN61529.1| lysine requiring protein [Saccharomyces cerevisiae YJM789]
Length = 373
Score = 456 bits (1175), Expect = e-127, Method: Composition-based stats.
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 361 DRHCARVKRSSRL 373
>pdb|2QRJ|A Chain A, Crystal Structure Of Sulfate-Bound Saccharopine
Dehydrogenase (L-Lys Forming) From Saccharomyces
Cerevisiae
pdb|2QRK|A Chain A, Crystal Structure Of Amp-Bound Saccharopine Dehydrogenase
(L-Lys Forming) From Saccharomyces Cerevisiae
pdb|2QRL|A Chain A, Crystal Structure Of Oxalylglycine-Bound Saccharopine
Dehydrogenase (L-Lys Forming) From Saccharomyces
Cerevisiae
Length = 394
Score = 456 bits (1174), Expect = e-126, Method: Composition-based stats.
Identities = 373/373 (100%), Positives = 373/373 (100%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 22 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 81
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
Sbjct: 82 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 141
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 142 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 201
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 202 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 261
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 262 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 321
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 322 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 381
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 382 DRHCARVKRSSRL 394
>ref|XP_446267.1| unnamed protein product [Candida glabrata]
sp|Q6FU27|LYS1_CANGA Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
emb|CAG59191.1| unnamed protein product [Candida glabrata CBS 138]
Length = 372
Score = 456 bits (1174), Expect = e-126, Method: Composition-based stats.
Identities = 302/373 (80%), Positives = 330/373 (88%), Gaps = 1/373 (0%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M+ VTLHLR ETKPLE RAALTPTTVK LI KGFKIYVE+SPQS F I+EYR+AGAIIVP
Sbjct: 1 MS-VTLHLRGETKPLEHRAALTPTTVKHLIGKGFKIYVEESPQSIFKIDEYRRAGAIIVP 59
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW +APRDRIIIGLKEMPE D FPLVHEHIQFAHCYKDQAGW++VL RFI G+GTLYD
Sbjct: 60 FGSWISAPRDRIIIGLKEMPEEDKFPLVHEHIQFAHCYKDQAGWKDVLRRFINGNGTLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLE+D GRRVAAFGFYAGFAGAALG+ DWAFKQTH D EDLPAVSPYPNEKAL+KD+
Sbjct: 120 LEFLEDDNGRRVAAFGFYAGFAGAALGLADWAFKQTHKDSEDLPAVSPYPNEKALIKDIG 179
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K YK AL TGA+KP VLIIGALGRCGSGAID L KVG+P+ NI+KWDI+ETSRGGPF EI
Sbjct: 180 KAYKNALKTGAKKPKVLIIGALGRCGSGAIDFLKKVGLPEENIIKWDIQETSRGGPFPEI 239
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+DIFINCIYLSKPIAPF N E LN P+R+LRTVVDVSADTTNPHNPIPIY +ATVFNK
Sbjct: 240 AASDIFINCIYLSKPIAPFINYELLNKPDRKLRTVVDVSADTTNPHNPIPIYNIATVFNK 299
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTV V T++GPKLSVISIDHLPSLLPREASEFF+HDLLPSLE LP R +PVWVRA+KLF
Sbjct: 300 PTVKVNTSSGPKLSVISIDHLPSLLPREASEFFAHDLLPSLEQLPSRHVSPVWVRAEKLF 359
Query: 361 DRHCARVKRSSRL 373
+RH AR R S+L
Sbjct: 360 NRHSARAIRESKL 372
>pdb|2Q99|A Chain A, Crystal Structure Of Saccharopine Dehydrogenase From
Saccharomyces Cerevisiae
Length = 381
Score = 455 bits (1172), Expect = e-126, Method: Composition-based stats.
Identities = 370/373 (99%), Positives = 370/373 (99%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
Sbjct: 9 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 68
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
AGSWKTAPRDRIIIGLKE PETDTFPLVHEHIQFAHCYKDQAGWQNVL RFIKGHGTLYD
Sbjct: 69 AGSWKTAPRDRIIIGLKEXPETDTFPLVHEHIQFAHCYKDQAGWQNVLXRFIKGHGTLYD 128
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
Sbjct: 129 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 188
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
Sbjct: 189 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 248
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
PQADIFINCIYLSKPIAPFTN EKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
Sbjct: 249 PQADIFINCIYLSKPIAPFTNXEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 308
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
Sbjct: 309 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 368
Query: 361 DRHCARVKRSSRL 373
DRHCARVKRSSRL
Sbjct: 369 DRHCARVKRSSRL 381
>ref|XP_001387327.1| Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH) [Pichia
stipitis CBS 6054]
gb|EAZ63304.1| Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH) [Pichia
stipitis CBS 6054]
Length = 371
Score = 455 bits (1171), Expect = e-126, Method: Composition-based stats.
Identities = 271/369 (73%), Positives = 307/369 (83%), Gaps = 1/369 (0%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
V LHLRAETKPLE RAALTPTT K+LI GFKI+VE S QSTF I EY QAGA IVP
Sbjct: 3 TPVILHLRAETKPLEHRAALTPTTTKQLIDAGFKIFVEKSSQSTFAIEEYEQAGATIVPE 62
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWK AP+DRIIIGLKE+PE +TFPLVHEHIQFAHCYKDQ GW++VL RF G+GTLYDL
Sbjct: 63 GSWKEAPKDRIIIGLKELPEDETFPLVHEHIQFAHCYKDQGGWKDVLSRFPAGNGTLYDL 122
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
EFLEND GRRVAAFGFYAGFAGAA+GVRDWAFKQ H D E+L ++PYPNE L+ DV K
Sbjct: 123 EFLENDTGRRVAAFGFYAGFAGAAIGVRDWAFKQLHPDSENLGGLTPYPNEDGLIADVKK 182
Query: 182 DYKEAL-ATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
D + AL G + PT L+IGALGRCGSGAIDL KVGIP+ NI KWDI+ET++GGPF EI
Sbjct: 183 DLEAALQKNGGQYPTTLVIGALGRCGSGAIDLFRKVGIPEENITKWDIQETAKGGPFKEI 242
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
++DIF+NCIYLS+PI PF + LN P+R+LR +VDVSADTTNPHNPIP+Y++ATVFN
Sbjct: 243 VESDIFVNCIYLSQPIPPFIDYSSLNVPDRKLRIIVDVSADTTNPHNPIPVYSIATVFND 302
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTV+V TTAGPKLSV SIDHLPSLLPREASEFFS DLLPSL LP+R+TAPVW RAK LF
Sbjct: 303 PTVVVETTAGPKLSVCSIDHLPSLLPREASEFFSRDLLPSLLQLPERQTAPVWTRAKALF 362
Query: 361 DRHCARVKR 369
D+H AR+
Sbjct: 363 DKHVARLSE 371
>ref|XP_457987.1| hypothetical protein DEHA0C07832g [Debaryomyces hansenii CBS767]
emb|CAG86045.1| unnamed protein product [Debaryomyces hansenii CBS767]
Length = 370
Score = 445 bits (1145), Expect = e-123, Method: Composition-based stats.
Identities = 267/367 (72%), Positives = 309/367 (84%), Gaps = 1/367 (0%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
+ VTLHLRAETKPLEARAALTP+T K+L+ GFK+YVE S QSTF+ +EY + GA IVP
Sbjct: 3 SPVTLHLRAETKPLEARAALTPSTTKQLLDAGFKVYVEKSSQSTFDADEYEKVGATIVPE 62
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWK AP+DRII GLKE+PE +TFPLVHEHIQFAHCYKDQ GW++VL RF +G GTLYDL
Sbjct: 63 GSWKEAPKDRIIFGLKELPEDETFPLVHEHIQFAHCYKDQGGWKDVLRRFPEGKGTLYDL 122
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
EFLENDQGRRVAAFGFYAGFAGAA+GV DWAFKQTHSD+EDL V+PYPNE L+ DV K
Sbjct: 123 EFLENDQGRRVAAFGFYAGFAGAAIGVMDWAFKQTHSDNEDLRGVTPYPNEDELIADVKK 182
Query: 182 DYKEALAT-GARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
EAL G P L+IGALGRCGSGA+D KVGIPD ++KWD+KET++GGPF EI
Sbjct: 183 VLDEALKKNGGEYPQCLVIGALGRCGSGALDFFKKVGIPDEKLIKWDMKETAKGGPFQEI 242
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
Q+DIF+NCIYLS+PI PF + E LN P+R+LRT+VDVSADTTNPHNPIP+Y++ATVFN
Sbjct: 243 VQSDIFVNCIYLSQPIPPFIDYEGLNVPDRKLRTIVDVSADTTNPHNPIPVYSIATVFND 302
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTV V T+AGPKLSV SIDHLPSLLPREASEFF+ DL+PSL LP R T+PVWVRAK+LF
Sbjct: 303 PTVPVETSAGPKLSVCSIDHLPSLLPREASEFFAKDLMPSLLELPNRDTSPVWVRAKQLF 362
Query: 361 DRHCARV 367
D+H AR+
Sbjct: 363 DKHVARL 369
>sp|P43065|LYS1_CANAL Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAA21362.1| saccharopine dehydrogenase
Length = 382
Score = 444 bits (1143), Expect = e-123, Method: Composition-based stats.
Identities = 262/379 (69%), Positives = 306/379 (80%), Gaps = 10/379 (2%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
+ V LHLRAETKPLEARAALTP+T K+L+ GF+IYVE+S QSTF+I EY GA IVP
Sbjct: 4 SPVILHLRAETKPLEARAALTPSTTKQLLDAGFEIYVEESSQSTFDIKEYEAVGAKIVPE 63
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWKTAP++RII GLKE+PE +TFPL+HEHIQFAHCYKDQAGWQ+VL RF +G+G LYDL
Sbjct: 64 GSWKTAPKERIIFGLKELPENETFPLIHEHIQFAHCYKDQAGWQDVLKRFPQGNGILYDL 123
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDED---------LPAVSPYPNE 172
EFLENDQGRRVAAFGFYAGFAGAA+GV DW+FKQ + + + LP V+PYPNE
Sbjct: 124 EFLENDQGRRVAAFGFYAGFAGAAIGVLDWSFKQLNGNTKGTKGEGEGGELPGVTPYPNE 183
Query: 173 KALVKDVTKDYKEAL-ATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKET 231
L+KDV + ++AL G + P L+IGALGRCGSGAIDL K+GIPD NI KWD+ ET
Sbjct: 184 NELIKDVKIELEKALTKNGGQYPKCLVIGALGRCGSGAIDLFKKIGIPDDNIAKWDMAET 243
Query: 232 SRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPI 291
++GGPF EI +DIFINCIYLSKPI PF N E LNN NR+L T+VDVSADTTNPHNPIP+
Sbjct: 244 AKGGPFQEIVDSDIFINCIYLSKPIPPFINKEILNNENRKLTTIVDVSADTTNPHNPIPV 303
Query: 292 YTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAP 351
Y +ATVFN+PTV V GPKLSV SIDHLPSLLPREASEFF+ DL+PSL LP R T+P
Sbjct: 304 YEIATVFNEPTVEVKLDKGPKLSVCSIDHLPSLLPREASEFFAKDLMPSLLELPNRDTSP 363
Query: 352 VWVRAKKLFDRHCARVKRS 370
VWVRAK+LFD+H AR+ +
Sbjct: 364 VWVRAKQLFDKHVARLDKE 382
>ref|XP_001643683.1| hypothetical protein Kpol_1057p13 [Vanderwaltozyma polyspora DSM
70294]
gb|EDO15825.1| hypothetical protein Kpol_1057p13 [Vanderwaltozyma polyspora DSM
70294]
Length = 371
Score = 442 bits (1138), Expect = e-122, Method: Composition-based stats.
Identities = 280/371 (75%), Positives = 316/371 (85%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
TLHLRAETKPLEARAALTP+TVK LI KGFKIYVE+SPQS FN++EYR+ GA IVP G
Sbjct: 1 MTTLHLRAETKPLEARAALTPSTVKSLIKKGFKIYVEESPQSVFNVDEYRRCGATIVPFG 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW +APRDRIIIGLKEMPE D FPLVH+HIQFAHCYKDQ GW+ VL RFI G GTLYDLE
Sbjct: 61 SWISAPRDRIIIGLKEMPEEDVFPLVHDHIQFAHCYKDQEGWEKVLRRFINGQGTLYDLE 120
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
FLE+D G+RVAAFGFYAGFAGAALG++DWAFK+TH D EDL A++PYPNEKAL++D++ +
Sbjct: 121 FLEDDNGKRVAAFGFYAGFAGAALGLKDWAFKKTHDDSEDLGALTPYPNEKALLRDISHE 180
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
YK+AL TGA+ P VLIIGALGRCGSGAID L K+GIP NI+KWD++ET++GGPF EI
Sbjct: 181 YKQALKTGAKAPKVLIIGALGRCGSGAIDFLTKIGIPQENIIKWDMQETAKGGPFQEIVD 240
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
DIF+NCIYLSKPI PF NM LN +R L TVVDVSADTTNP+NPIPIY +ATVFNKPT
Sbjct: 241 TDIFVNCIYLSKPIPPFVNMSMLNQDSRHLTTVVDVSADTTNPYNPIPIYNIATVFNKPT 300
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V VPT GPKLSVISIDHLPSL+PREASE F+ DLLPSLELLP R APVW RA LF+R
Sbjct: 301 VTVPTKKGPKLSVISIDHLPSLMPREASEAFAKDLLPSLELLPNRHVAPVWTRAYSLFNR 360
Query: 363 HCARVKRSSRL 373
H AR RSS+L
Sbjct: 361 HSARAYRSSKL 371
>ref|XP_001213891.1| hypothetical protein ATEG_04713 [Aspergillus terreus NIH2624]
gb|EAU35160.1| hypothetical protein ATEG_04713 [Aspergillus terreus NIH2624]
Length = 988
Score = 442 bits (1138), Expect = e-122, Method: Composition-based stats.
Identities = 212/377 (56%), Positives = 264/377 (70%), Gaps = 6/377 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M + + LRAETKP EAR+ALTPTT K LI G+ + VE S Q F +E+ + GA +V
Sbjct: 612 MPSNKIWLRAETKPAEARSALTPTTAKALIDAGYDVTVERSKQRIFEDDEFPKIGAKLVE 671
Query: 61 AGSWK-TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW AP+D I+GLKE+PE D FPL H HI FAHCYK Q GW+ VL R+ +G GTL
Sbjct: 672 EGSWVKDAPKDAFILGLKELPEDD-FPLEHVHISFAHCYKQQGGWEKVLSRWPRGGGTLL 730
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP PY N+ L++ V
Sbjct: 731 DLEFLTDDAGRRVAAFGYSAGYAGSALAVKNWAWQLTHPEGEPLPGEVPYANQDLLIQSV 790
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + R P VL+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 791 KESLEAGKKASGRSPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDMEETKKGGPFRE 850
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIF+NCIYLS PI PF N E L++PNRRL + DVSADTTNPHNPIP+YTV T F
Sbjct: 851 IIEDADIFVNCIYLSSPIPPFLNGETLSSPNRRLSVICDVSADTTNPHNPIPVYTVTTTF 910
Query: 299 NKPTVLV---PTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
++PTV V T GP LSVISIDHLPSLLPRE+SE FS LLPSL L + A VW +
Sbjct: 911 DRPTVPVILPAGTQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDWQNARVWKQ 970
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF A + S R
Sbjct: 971 AEDLFKEKVATLPESMR 987
>ref|XP_454310.1| unnamed protein product [Kluyveromyces lactis]
emb|CAG99397.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
Length = 372
Score = 441 bits (1136), Expect = e-122, Method: Composition-based stats.
Identities = 284/373 (76%), Positives = 323/373 (86%), Gaps = 1/373 (0%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M+ VTLHLRAETKPLEAR ALTPTT KKL+ KGFKI+VE+S QS F+I EY++ GA IVP
Sbjct: 1 MS-VTLHLRAETKPLEARTALTPTTTKKLLDKGFKIFVEESSQSAFDIEEYKKVGATIVP 59
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYK+QAGW++VL RF +G+G LYD
Sbjct: 60 EGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKNQAGWEDVLSRFKRGNGVLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFLENDQGRRVAAFGFYAGFAGAA+G+RDWAFKQTHSD E+L A+ PY NE+A++KDV
Sbjct: 120 LEFLENDQGRRVAAFGFYAGFAGAAVGIRDWAFKQTHSDSENLGAIEPYENEEAMIKDVR 179
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
+DY+ AL GARKP VLIIGALGRCGSGA DLL K G+P+ NI+KWD+KET+RGGPF EI
Sbjct: 180 RDYQLALKRGARKPKVLIIGALGRCGSGAADLLRKCGLPEENIIKWDMKETARGGPFQEI 239
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
AD+FINCIYLSKPI PF N E LN P RRLRTVVDVSADTTNPHNP+PIYT+ T F+
Sbjct: 240 ADADVFINCIYLSKPIPPFINNELLNKPTRRLRTVVDVSADTTNPHNPVPIYTINTTFDA 299
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTV VPTT GPKLSV SIDHLPSLLP+EASE FS DLLPSLE LPQR TA VWV+A+ L+
Sbjct: 300 PTVQVPTTVGPKLSVCSIDHLPSLLPKEASESFSRDLLPSLEQLPQRATASVWVKARNLY 359
Query: 361 DRHCARVKRSSRL 373
++ A+V R+S+L
Sbjct: 360 EKFAAKVGRTSKL 372
>ref|XP_001399884.1| hypothetical protein An02g07500 [Aspergillus niger]
emb|CAK37714.1| unnamed protein product [Aspergillus niger]
Length = 377
Score = 441 bits (1134), Expect = e-122, Method: Composition-based stats.
Identities = 206/377 (54%), Positives = 263/377 (69%), Gaps = 6/377 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F+ ++ + GA +V
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSTQRIFDDEDFAKIGAPLVE 60
Query: 61 AGSWK-TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW AP+D I+GLKE+PE D FPL H HI FAHCYK Q GW+ VL R+ +G GTL
Sbjct: 61 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQGGWEQVLSRWPRGGGTLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP PY N+ AL++ V
Sbjct: 120 DLEFLTDDVGRRVAAFGWSAGYAGSALAVKNWAWQLTHPEGEPLPGEVPYINQDALIESV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
K ++ R P +L+IGALGRCGSGA+ L VGIPD++I++WDI+ET +GGPF E
Sbjct: 180 KKSLEDGKKQSGRSPKILVIGALGRCGSGAVQLAKDVGIPDSDIVRWDIEETKKGGPFRE 239
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + DI +NCIYLS I PF E L +P RRL + DVSADTTNPHNP+P+Y++ T F
Sbjct: 240 IVEDVDILVNCIYLSAQIPPFVTPETLTSPKRRLSVICDVSADTTNPHNPLPVYSITTTF 299
Query: 299 NKPTVLVPTTAGP---KLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV V G LSVISIDHLPSLLPRE+SE FS LLPSL L R+ A VW +
Sbjct: 300 DKPTVPVTLAGGNQVAGLSVISIDHLPSLLPRESSEMFSQALLPSLLQLKDRQNARVWKQ 359
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF+ A + S R
Sbjct: 360 AEDLFNEKVATLPESLR 376
>ref|XP_660477.1| hypothetical protein AN2873.2 [Aspergillus nidulans FGSC A4]
gb|EAA63444.1| hypothetical protein AN2873.2 [Aspergillus nidulans FGSC A4]
Length = 1026
Score = 441 bits (1134), Expect = e-122, Method: Composition-based stats.
Identities = 204/378 (53%), Positives = 267/378 (70%), Gaps = 6/378 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M + + LRAETKP EAR+ALTPTT K LI G+++ VE S Q F+ +E+ + GA +V
Sbjct: 1 MGSNKIWLRAETKPAEARSALTPTTCKALIDAGYEVTVERSTQRIFDDDEFAKVGAPLVE 60
Query: 61 AGSWK-TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW AP+D I+GLKE+PE D FPL H HI FAHCYK+QAGW+ VL R+ +G G L
Sbjct: 61 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKEQAGWEKVLSRWPRGGGVLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFGF AG+AGAAL V++WA++ TH + E L PY N+ L++ V
Sbjct: 120 DLEFLTDDAGRRVAAFGFSAGYAGAALAVKNWAWQLTHPEGEPLAGEKPYANQDLLIQSV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + + P +L+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 180 KESLQAGQKQSGKSPKILVIGALGRCGKGAVQLAKDVGIPESDIIQWDMEETKKGGPFKE 239
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIF+NCIYLS I F N+E L+ P+RRL + DVSADTTNP+NPIP+Y + T F
Sbjct: 240 IVEDADIFVNCIYLSSKIPHFVNVESLSTPSRRLSVICDVSADTTNPNNPIPVYNITTTF 299
Query: 299 NKPTVLV---PTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV V T G LSVISIDHLPSLLPRE+SE FS L+PSL L R+ A VW +
Sbjct: 300 DKPTVPVTLPNGTQGTPLSVISIDHLPSLLPRESSEMFSEALMPSLLQLKDRENARVWKQ 359
Query: 356 AKKLFDRHCARVKRSSRL 373
A+ LF++ A + +++ L
Sbjct: 360 AEDLFNQKVATLPQTAEL 377
>ref|XP_001523078.1| saccharopine dehydrogenase [Lodderomyces elongisporus NRRL YB-4239]
gb|EDK47443.1| saccharopine dehydrogenase [Lodderomyces elongisporus NRRL YB-4239]
Length = 370
Score = 440 bits (1133), Expect = e-122, Method: Composition-based stats.
Identities = 274/370 (74%), Positives = 308/370 (83%), Gaps = 3/370 (0%)
Query: 1 MA--AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAII 58
M+ V LHLRAETKPLEARAALTPTT K+L+ GFK+YVE+S QSTFN EY GA I
Sbjct: 1 MSSNPVILHLRAETKPLEARAALTPTTTKQLLDAGFKVYVEESSQSTFNAKEYEAVGAEI 60
Query: 59 VPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTL 118
VP GSWK AP+DRII GLKE+PE DTFPLVH HIQFAHCYK+QAGW+ VL RF G+GTL
Sbjct: 61 VPEGSWKDAPKDRIIFGLKELPENDTFPLVHTHIQFAHCYKNQAGWEKVLGRFPAGNGTL 120
Query: 119 YDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKD 178
YDLEFLENDQGRRVAAFGFYAGFAGAA+GV DWAFKQ H DDE+LP VSPYPNE AL+KD
Sbjct: 121 YDLEFLENDQGRRVAAFGFYAGFAGAAIGVLDWAFKQLHGDDENLPGVSPYPNEDALIKD 180
Query: 179 VTKDYKEALAT-GARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPF 237
V + +ALA G + PT L+IGALGRCGSGAIDL KVGIPD N+ KWD+ ET++GGPF
Sbjct: 181 VKTELDKALAKNGGKYPTALVIGALGRCGSGAIDLFKKVGIPDDNVAKWDMAETAKGGPF 240
Query: 238 DEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATV 297
EI +IF+NCIYLS+PIAPF N E LN P R+L T+VDVSADTTNPHNPIP+Y +ATV
Sbjct: 241 KEIVDTNIFVNCIYLSQPIAPFINYETLNVPERKLTTIVDVSADTTNPHNPIPVYEIATV 300
Query: 298 FNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAK 357
FN PTV V TTAGPKLSV SIDHLPSLLPREASEFFS DL+PSL LP+R TAPVWVRAK
Sbjct: 301 FNDPTVPVKTTAGPKLSVCSIDHLPSLLPREASEFFSKDLMPSLLQLPERDTAPVWVRAK 360
Query: 358 KLFDRHCARV 367
+LFD++ AR+
Sbjct: 361 QLFDKNVARL 370
>ref|XP_754450.1| saccharopine dehydrogenase Lys1 [Aspergillus fumigatus Af293]
gb|EAL92412.1| saccharopine dehydrogenase Lys1, putative [Aspergillus fumigatus
Af293]
gb|EDP52582.1| saccharopine dehydrogenase Lys1, putative [Aspergillus fumigatus
A1163]
Length = 374
Score = 438 bits (1128), Expect = e-121, Method: Composition-based stats.
Identities = 211/377 (55%), Positives = 267/377 (70%), Gaps = 9/377 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F + Q GA +V
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSRQRIF---DVVQIGAPLVE 57
Query: 61 AGSWK-TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW AP+D I+GLKE+PE D FPL H HI FAHCYK QAGW+ VL R+ +G GTL
Sbjct: 58 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQAGWEKVLSRWPRGGGTLL 116
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL ++ GRRVAAFG+ AG+AG+AL +++WA++ TH + E LP +PY N+ L++ V
Sbjct: 117 DLEFLTDETGRRVAAFGYSAGYAGSALAIKNWAWQLTHPEGEPLPGETPYANQDLLIESV 176
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + R P VL+IGALGRCG GA+ L VGIP+++I++WDI+ET +GGPF E
Sbjct: 177 KESLESGKKLSGRPPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDIEETKKGGPFRE 236
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIFINCIYLS I PF N E L++PNRRL + DVSADTTNP+NPIP+Y++ T F
Sbjct: 237 IVEDADIFINCIYLSAKIPPFVNTETLSSPNRRLSVICDVSADTTNPNNPIPVYSITTTF 296
Query: 299 NKPTVLVP---TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV VP GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A VW +
Sbjct: 297 DKPTVTVPLPELAQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDRKNARVWKQ 356
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF+ A + S R
Sbjct: 357 AEDLFNEKVATLPESMR 373
>ref|XP_001263295.1| saccharopine dehydrogenase Lys1, putative [Neosartorya fischeri
NRRL 181]
gb|EAW21398.1| saccharopine dehydrogenase Lys1, putative [Neosartorya fischeri
NRRL 181]
Length = 374
Score = 438 bits (1128), Expect = e-121, Method: Composition-based stats.
Identities = 210/377 (55%), Positives = 267/377 (70%), Gaps = 9/377 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F + Q GA +V
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYEVTVERSTQRIF---DVVQIGAPLVE 57
Query: 61 AGSWK-TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW AP+D I+GLKE+PE D FPL H HI FAHCYK QAGW+ VL R+ +G GTL
Sbjct: 58 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKQQAGWEKVLSRWPRGGGTLL 116
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFG+ AG+AG+AL +++WA++ TH + E LP +PY N+ L++ V
Sbjct: 117 DLEFLTDDTGRRVAAFGYSAGYAGSALAIKNWAWQLTHPEGEPLPGETPYANQDLLIESV 176
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + R P VL+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 177 KESLESGKKLSGRPPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDLEETKKGGPFRE 236
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIFINCIYLS I PF N E L++P RRL + DVSADTTNP+NPIP+Y++ T F
Sbjct: 237 IVEDADIFINCIYLSAKIPPFVNTETLSSPKRRLSVICDVSADTTNPNNPIPVYSITTTF 296
Query: 299 NKPTVLVPTTA---GPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV VP + GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A VW +
Sbjct: 297 DKPTVTVPLSERAQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDRKNARVWEQ 356
Query: 356 AKKLFDRHCARVKRSSR 372
A+ LF+ A + S R
Sbjct: 357 AEDLFNEKVATLPESIR 373
>ref|XP_500931.1| YlLYS5 [Yarrowia lipolytica]
sp|P38997|LYS1_YARLI Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAA35248.1| saccharopine dehydrogenase
emb|CAG83182.1| YlLYS5 [Yarrowia lipolytica CLIB122]
Length = 369
Score = 438 bits (1127), Expect = e-121, Method: Composition-based stats.
Identities = 248/368 (67%), Positives = 288/368 (78%), Gaps = 1/368 (0%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
A V LHLRAETKPLE R+ALTPTT +KL+ GF+++VE SP F+ E+ GA +V
Sbjct: 3 APVKLHLRAETKPLEHRSALTPTTTRKLLDAGFEVFVEKSPLRIFDDQEFVDVGATLVEE 62
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSW +AP DR+IIGLKE+PE FPL HEHIQFAHCYKDQ GW++VL RF G+GTLYDL
Sbjct: 63 GSWVSAPEDRMIIGLKELPEES-FPLSHEHIQFAHCYKDQGGWKDVLSRFPAGNGTLYDL 121
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
EFLE+D GRRVAAFGF+AGFAGAA+GV WAF+QTH D E+LP VS YPNE LV + K
Sbjct: 122 EFLEDDNGRRVAAFGFHAGFAGAAIGVETWAFQQTHPDSENLPGVSAYPNETELVDKIKK 181
Query: 182 DYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIP 241
D A+ G++ PTVL+IGALGRCGSGAIDL KVGIP+ NI++WD+ ET +GGPF EI
Sbjct: 182 DLAAAVEKGSKLPTVLVIGALGRCGSGAIDLARKVGIPEENIIRWDMNETKKGGPFQEIA 241
Query: 242 QADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKP 301
ADIFINCIYLS+PI PF N + LN R+L +VDVSADTTNPHNP+P+YT+AT F+ P
Sbjct: 242 DADIFINCIYLSQPIPPFINYDLLNKETRKLSVIVDVSADTTNPHNPVPVYTIATTFDHP 301
Query: 302 TVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFD 361
TV V TTAGPKLSV SIDHLPSLLPREASE FS LLPSL LPQR TAPVW RAK LFD
Sbjct: 302 TVPVETTAGPKLSVCSIDHLPSLLPREASEAFSEALLPSLLQLPQRDTAPVWTRAKALFD 361
Query: 362 RHCARVKR 369
+H R+
Sbjct: 362 KHVLRIGE 369
>ref|XP_001271170.1| saccharopine dehydrogenase Lys1, putative [Aspergillus clavatus
NRRL 1]
gb|EAW09744.1| saccharopine dehydrogenase Lys1, putative [Aspergillus clavatus
NRRL 1]
Length = 380
Score = 428 bits (1102), Expect = e-118, Method: Composition-based stats.
Identities = 208/381 (54%), Positives = 263/381 (69%), Gaps = 11/381 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINE----YRQAGA 56
M++ + LRAETKP EAR+ALTPTT K L+ G+ + VE S Q F+ + Y GA
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTCKALMDAGYDVTVERSTQRIFDGEDNILSYL-IGA 59
Query: 57 IIVPAGSWK-TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
+V GSW AP+D ++GLKE+PE D FPL H HI FAHCYK+Q GW+ VL R+ +G
Sbjct: 60 PLVEEGSWVKDAPKDAYVLGLKELPEDD-FPLEHVHISFAHCYKEQGGWEKVLSRWPRGG 118
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKAL 175
GTL DLEFL +D GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP +PY N+ L
Sbjct: 119 GTLLDLEFLTDDVGRRVAAFGYSAGYAGSALAVKNWAWQLTHPEGEPLPGETPYENQDLL 178
Query: 176 VKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGG 235
+ V + + + P VL+IGALGRCG GA+ L VGIP+++I++WDI+ET +GG
Sbjct: 179 IASVKESLEVGKKQSGKSPKVLVIGALGRCGKGAVQLAKDVGIPESDIIQWDIEETKKGG 238
Query: 236 PFDEIPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTV 294
PF EI + DIF+NCIYLS I PF N E L+ PNRRL + DVSADTTNPHNPIP+Y++
Sbjct: 239 PFREIVEDVDIFVNCIYLSAKIPPFVNAETLSTPNRRLSVICDVSADTTNPHNPIPVYSI 298
Query: 295 ATVFNKPTVLVP---TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAP 351
T F+KPTV V GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A
Sbjct: 299 TTTFDKPTVPVTLSAGAQGPPLSVISIDHLPSLLPRESSEMFSEALLPSLLQLKDRKNAR 358
Query: 352 VWVRAKKLFDRHCARVKRSSR 372
VW +A+ LF+ A + S R
Sbjct: 359 VWKQAEDLFNEKVATLPESMR 379
>sp|Q870G1|LYS1_EMENI Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAL23682.1| putative saccharopine dehydrogenase [Emericella nidulans]
Length = 375
Score = 425 bits (1093), Expect = e-117, Method: Composition-based stats.
Identities = 203/376 (53%), Positives = 264/376 (70%), Gaps = 6/376 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M + + LRAETKP EAR+ALTPTT K LI G+++ VE S Q F+ + Q GA +V
Sbjct: 1 MGSNKIWLRAETKPAEARSALTPTTCKALIDAGYEVTVERSTQRIFDGKIFVQVGAPLVE 60
Query: 61 AGSWK-TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
GSW AP+D I+GLKE+PE D FPL H HI FAHCYK+QAGW+ VL R+ +G G L
Sbjct: 61 EGSWVKDAPKDAYILGLKELPEDD-FPLEHVHISFAHCYKEQAGWEKVLSRWPRGGGVLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D GRRVAAFGF AG+AGAAL V++WA++ TH + E L PY N+ L++ V
Sbjct: 120 DLEFLTDDAGRRVAAFGFSAGYAGAALAVKNWAWQLTHPEGEPLAGEKPYANQDLLIQSV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + + P +L+IGALGRCG GA+ L VGIP+++I++WD++ET +GGPF E
Sbjct: 180 KESLQAGQKQSGKSPKILVIGALGRCGKGAVQLAKDVGIPESDIIQWDMEETKKGGPFKE 239
Query: 240 IPQ-ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
I + ADIF+NCIYLS I F N+E L+ P+RRL + DVSADTTNP+NPIP+Y + T F
Sbjct: 240 IVEDADIFVNCIYLSSKIPHFVNVESLSTPSRRLSVICDVSADTTNPNNPIPVYNITTTF 299
Query: 299 NKPTVLV---PTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVR 355
+KPTV V T G LSVISIDHLPSLLPRE+SE FS L+PSL L R+ A VW +
Sbjct: 300 DKPTVPVTLPNGTQGTPLSVISIDHLPSLLPRESSEMFSEALMPSLLQLKDRENARVWKQ 359
Query: 356 AKKLFDRHCARVKRSS 371
A+ LF++ A + +++
Sbjct: 360 AEDLFNQKVATLPQTA 375
>ref|XP_001482345.1| hypothetical protein PGUG_05365 [Pichia guilliermondii ATCC 6260]
gb|EDK41267.1| hypothetical protein PGUG_05365 [Pichia guilliermondii ATCC 6260]
Length = 370
Score = 424 bits (1091), Expect = e-117, Method: Composition-based stats.
Identities = 254/367 (69%), Positives = 304/367 (82%), Gaps = 1/367 (0%)
Query: 2 AAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPA 61
A V+LHLRAETKPLEARA L+P+ K+L+ GFK+YVE S QSTF+ +EY + GA IVP
Sbjct: 3 APVSLHLRAETKPLEARAGLSPSVTKELLDAGFKVYVEKSSQSTFDADEYAKVGAEIVPE 62
Query: 62 GSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDL 121
GSWK AP+DRII GLK +PE +TFPLVHEHIQFAHCYKDQAGW++VL RF G+GTLYDL
Sbjct: 63 GSWKEAPKDRIIYGLKALPEDETFPLVHEHIQFAHCYKDQAGWKDVLSRFPAGNGTLYDL 122
Query: 122 EFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTK 181
EFL ND+GRRVAAFGFYAGFAGAA+G++DWAFKQTH+D+E+L V+PY E+ L+KDV +
Sbjct: 123 EFLVNDEGRRVAAFGFYAGFAGAAIGLKDWAFKQTHADNEELRGVTPYATEEELIKDVKE 182
Query: 182 DYKEALAT-GARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
D ALA G + P L+IGALGRCGSGA+ L K GIPD IL+WD+KET+RGGPF+EI
Sbjct: 183 DLDAALAKNGGKYPQCLVIGALGRCGSGAVSLFKKAGIPDEKILQWDMKETARGGPFEEI 242
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+DIFINCIYLS+PI PF + E LN+ R+LRT+VDVSADTTNP+NPIP+YTV T F+K
Sbjct: 243 TDSDIFINCIYLSQPIPPFVSSETLNSEKRKLRTIVDVSADTTNPNNPIPVYTVITDFDK 302
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PT LV TTAGPKLSV SIDHLPSL+PREASE F+ DLLP+L LP R TAPV+ RAK+LF
Sbjct: 303 PTALVETTAGPKLSVCSIDHLPSLVPREASETFAKDLLPTLLQLPDRNTAPVYQRAKQLF 362
Query: 361 DRHCARV 367
++H AR+
Sbjct: 363 EKHVARL 369
>ref|XP_001246345.1| hypothetical protein CIMG_00116 [Coccidioides immitis RS]
gb|EAS34762.1| hypothetical protein CIMG_00116 [Coccidioides immitis RS]
Length = 385
Score = 424 bits (1091), Expect = e-117, Method: Composition-based stats.
Identities = 203/384 (52%), Positives = 256/384 (66%), Gaps = 15/384 (3%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAG 55
MA TLHLRAE K LE R+ALTP+T + LI G+ I VE SP + F E+ +AG
Sbjct: 1 MAGTTLHLRAEDKILEHRSALTPSTTRALIDAGYNIKVERSPTSALRKRIFPDEEFEKAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +V GSW AP+D II+GLKE+ ET FPLVH+H+ FAHC+K+Q GW+ L R+ +G
Sbjct: 61 AELVAEGSWVNAPKDSIIVGLKELDETKDFPLVHDHVTFAHCFKNQGGWEKALGRWSRGG 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAV-------SP 168
G LYDLEFL++D GRRVAAFG++AGFAGAAL ++ WA++ H D LP V
Sbjct: 121 GVLYDLEFLQDDSGRRVAAFGYHAGFAGAALSLKTWAWQLEHPDGTPLPGVDEFTGGKGY 180
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE +V + D + RKP VLIIGALGRCG GA+D K G +IL+WD+
Sbjct: 181 YVNEDEMVNQIRADIERGAKIAGRKPRVLIIGALGRCGRGAVDACVKAG--CEDILRWDM 238
Query: 229 KETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNP 288
ET++GGPF EI ++DIFINCIYL+ I F + E L +PNR+L V DVS DTTNP+NP
Sbjct: 239 AETAKGGPFTEIVESDIFINCIYLTSKIPSFVDEESLKSPNRKLSVVCDVSCDTTNPNNP 298
Query: 289 IPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRK 348
IPIY V T F+KPT+ + T P LSVISIDHLPSLLP E+SE FS DLLPS+ + R
Sbjct: 299 IPIYNVNTTFDKPTLQLNYTNPP-LSVISIDHLPSLLPAESSEAFSTDLLPSMLEIKNRT 357
Query: 349 TAPVWVRAKKLFDRHCARVKRSSR 372
+ PVW RA+KL+ + +
Sbjct: 358 SHPVWQRAEKLYREKVQTLPAELQ 381
>ref|NP_983569.1| ACR167Cp [Ashbya gossypii ATCC 10895]
sp|Q75BV4|LYS1_ASHGO Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|AAS51393.1| ACR167Cp [Ashbya gossypii ATCC 10895]
Length = 372
Score = 424 bits (1090), Expect = e-117, Method: Composition-based stats.
Identities = 263/373 (70%), Positives = 315/373 (84%), Gaps = 1/373 (0%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M+A LHLRAETKP+EARAALTPTTV+ L++ GFKIYVE+S QS F EY AGA +V
Sbjct: 1 MSA-ILHLRAETKPMEARAALTPTTVRTLVSHGFKIYVEESAQSVFEAAEYAAAGAEVVA 59
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW+ APR+RII+GLKE+PE DTFPL H HIQFAHCYK+Q+GW+ VL RF G G LYD
Sbjct: 60 TGSWRGAPRERIIVGLKELPEEDTFPLEHTHIQFAHCYKNQSGWREVLGRFQSGGGLLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL++D+GRRVAAFG+YAGFAGAALG+RDWA+KQTH+D EDLPAV+PY NE+ALV +V
Sbjct: 120 LEFLQDDRGRRVAAFGYYAGFAGAALGLRDWAWKQTHTDAEDLPAVAPYENEQALVSEVA 179
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
+EA GARKP VL+IGALGRCGSGA++LL + G+ D +I++WDI ET+RGGPF EI
Sbjct: 180 AACEEAYKKGARKPRVLVIGALGRCGSGAVELLRQCGLHDKHIIRWDIAETARGGPFPEI 239
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
ADIFINCIYLS+PIAPF NME L+ P+R+LRT+VDVSADTTNPHNP+P+Y VATVF+
Sbjct: 240 AAADIFINCIYLSQPIAPFINMELLDRPDRKLRTIVDVSADTTNPHNPVPVYNVATVFSS 299
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
PTV+VPT+ GPKLSVISIDHLPSLLPREASE F+ DLLPSL LP+R TAPVW+RAK+LF
Sbjct: 300 PTVVVPTSQGPKLSVISIDHLPSLLPREASEAFASDLLPSLLQLPERDTAPVWLRAKELF 359
Query: 361 DRHCARVKRSSRL 373
+HC R+ + +RL
Sbjct: 360 QQHCERLSKEARL 372
>ref|XP_964977.1| saccharopine dehydrogenase [Neurospora crassa OR74A]
sp|Q7SFX6|LYS1_NEUCR Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
gb|EAA35741.1| saccharopine dehydrogenase [Neurospora crassa OR74A]
Length = 372
Score = 421 bits (1082), Expect = e-116, Method: Composition-based stats.
Identities = 223/372 (59%), Positives = 268/372 (72%), Gaps = 4/372 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MA LHLR+ETK LE R+ALTPTT +LI G+ + VE SP+ F+ E+ +AGA +VP
Sbjct: 1 MAPTVLHLRSETKHLEHRSALTPTTTAELIKAGYIVNVERSPERIFDDEEFEKAGATLVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
SW AP++ II+GLKE+ E FPL H H+QFAHCYK QAGW+NVL RF +G GTL D
Sbjct: 61 EHSWVDAPKEHIIVGLKEL-EEKDFPLKHVHVQFAHCYKQQAGWENVLARFPRGGGTLLD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL ++ GRRVAAFGF+AGFAGAAL + WA++ H E P V YPNE AL+ DV
Sbjct: 120 LEFLVDEHGRRVAAFGFHAGFAGAALALEVWAWQLNH--SEPFPGVESYPNEDALIADVK 177
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K KE + R P V++IGA GRCGSGA+ L K GIPD NIL WD+ ET++GGPF EI
Sbjct: 178 KAVKEGVEAAGRLPRVIVIGARGRCGSGAVSALKKAGIPDENILDWDMAETAKGGPFKEI 237
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+DIF+NCIYL+ I F NME L P+R+LR V DVSADTT+P P+PIYTVAT F+K
Sbjct: 238 TDSDIFVNCIYLTSKIPNFVNMESLQVPDRQLRVVCDVSADTTSPFTPVPIYTVATTFDK 297
Query: 301 PTVLVPT-TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
PTV V T+GP LSVISIDHLPSLLPREASE FSHDLLPSL L + +PVW RAK+L
Sbjct: 298 PTVPVDGLTSGPPLSVISIDHLPSLLPREASEAFSHDLLPSLLTLNDWQNSPVWARAKQL 357
Query: 360 FDRHCARVKRSS 371
FD A + S+
Sbjct: 358 FDEKVATLPESA 369
>ref|XP_001908761.1| unnamed protein product [Podospora anserina]
emb|CAP69434.1| unnamed protein product [Podospora anserina]
Length = 374
Score = 420 bits (1081), Expect = e-116, Method: Composition-based stats.
Identities = 219/372 (58%), Positives = 269/372 (72%), Gaps = 2/372 (0%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MA LHLR+ETKPLE R+ALTPTT LI G+ + VE SP+ F+ +E+ GA +VP
Sbjct: 1 MAPTVLHLRSETKPLEHRSALTPTTTAALIKAGYVVNVERSPERIFDDSEFEAVGATLVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW+ P++ II+GLKE+ E FPL H H+QFAHCYK QAGW+NVL RF +G GTL D
Sbjct: 61 EGSWEEVPKEHIIVGLKEL-EEKEFPLKHVHVQFAHCYKHQAGWENVLARFPRGGGTLLD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL +++GRRVAAFGF+AGFAGAAL + WA + TH P V+ YPNE AL+ +V
Sbjct: 120 LEFLVDERGRRVAAFGFHAGFAGAALALEVWAHQLTHPPSSPFPGVASYPNEDALITNVK 179
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K A R P V++IGALGRCGSGA+D L K G+P+ NILKWD+ ET++GGPF EI
Sbjct: 180 KALATGTAAAGRSPRVIVIGALGRCGSGAVDALRKAGVPEENILKWDMAETAKGGPFKEI 239
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+DIF+NCIYL+ I F N++ L P+R+L V DVSADTT+P P+PIYTVAT F+K
Sbjct: 240 TDSDIFVNCIYLTSKIPNFVNLDSLQVPDRKLSVVCDVSADTTSPFTPVPIYTVATTFDK 299
Query: 301 PTVLVPT-TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
PTV V ++GP LSVISIDHLPSLLPREASE FSHDLLPSL L + +PVW RAKKL
Sbjct: 300 PTVPVEGLSSGPALSVISIDHLPSLLPREASEAFSHDLLPSLLTLNDWQNSPVWARAKKL 359
Query: 360 FDRHCARVKRSS 371
FD A + S+
Sbjct: 360 FDEKVATLPASA 371
>ref|XP_001559795.1| saccharopine dehydrogenase [Botryotinia fuckeliana B05.10]
gb|EDN27084.1| saccharopine dehydrogenase [Botryotinia fuckeliana B05.10]
Length = 372
Score = 419 bits (1078), Expect = e-115, Method: Composition-based stats.
Identities = 215/371 (57%), Positives = 266/371 (71%), Gaps = 2/371 (0%)
Query: 1 MAAVTLHLRAET-KPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIV 59
M+ TLHLR+E K LE R+ALTPTT K LI G+ I VE SP+ F+ E+ + GA +V
Sbjct: 1 MSGTTLHLRSELGKALEHRSALTPTTAKALIDAGYTINVERSPERIFDDEEFEKVGATLV 60
Query: 60 PAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
P +W+ AP+D IIIGLKE+P + FPL H H+QFAHCYK Q GW VL RF +G GTL
Sbjct: 61 PENTWRQAPKDHIIIGLKELPVEE-FPLEHVHVQFAHCYKQQGGWDTVLSRFPRGGGTLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D+GRRVAAFG++AGFAGAAL + +WA++ TH E P+VS YPNE L+ DV
Sbjct: 120 DLEFLTDDRGRRVAAFGYHAGFAGAALALENWAWQLTHPASEPFPSVSSYPNEDELIVDV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
K + P VL+IGALGRCGSGA+DL + G+P N+LKWD+ ET++GGPF E
Sbjct: 180 KKAIAAGQEKTGKAPRVLVIGALGRCGSGAVDLCLRAGVPTENVLKWDMAETAKGGPFPE 239
Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
I ++DIFINCIYL I F +M+ L+ PNR+L V DVSADTTNP+NPIPIYTVAT F+
Sbjct: 240 IVESDIFINCIYLMSKIPNFVDMQSLDTPNRKLSVVCDVSADTTNPNNPIPIYTVATTFS 299
Query: 300 KPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
+PTV V P+LSVISIDHLPSLLPREASE FS DLLPSL L + PVW +A+KL
Sbjct: 300 EPTVPVEVKGEPRLSVISIDHLPSLLPREASEAFSKDLLPSLLSLKDWRNTPVWAKAEKL 359
Query: 360 FDRHCARVKRS 370
F A + ++
Sbjct: 360 FQEKVATLPKN 370
>ref|XP_001819876.1| hypothetical protein [Aspergillus oryzae RIB40]
dbj|BAE57874.1| unnamed protein product [Aspergillus oryzae]
Length = 377
Score = 414 bits (1066), Expect = e-114, Method: Composition-based stats.
Identities = 207/378 (54%), Positives = 263/378 (69%), Gaps = 11/378 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQA-----G 55
M++ + LRAETKP EAR+ALTPTT K L+ G+++ VE S Q F+ +A G
Sbjct: 1 MSSNKIWLRAETKPAEARSALTPTTAKALMDAGYEVTVERSTQRIFDGRLSIRAPLSRIG 60
Query: 56 AIIVPAGSW-KTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKG 114
A +V GSW K AP+D ++GLKE+PE D FPL H HI FAHCYK Q GW+ VL R+ +G
Sbjct: 61 APLVEEGSWAKDAPKDAYVLGLKELPEDD-FPLEHVHITFAHCYKQQGGWEKVLRRWPRG 119
Query: 115 HGTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKA 174
GTL DLEFL ++ GRRVAAFG+ AG+AG+AL V++WA++ TH + E LP PY N+
Sbjct: 120 GGTLLDLEFLTDEVGRRVAAFGWSAGYAGSALAVKNWAWQLTHPEGEPLPGEVPYANQDL 179
Query: 175 LVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRG 234
L + V + + R P +L+IGALGRCG+GA+ L VGIP+++I++WDI+ET +G
Sbjct: 180 LTQSVKESLEAGKKQSGRSPKILVIGALGRCGNGAVQLAKDVGIPESDIIRWDIEETKKG 239
Query: 235 GPFDEIPQADIFINCIYLSK-PIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYT 293
GPF EI ADIF+NCIYLS I PF N+E L+ PNRRL + DVSADTTNP+NPIP+Y
Sbjct: 240 GPFQEIIDADIFVNCIYLSSESIPPFVNVESLSTPNRRLSVICDVSADTTNPNNPIPVYD 299
Query: 294 VATVFNKPTVLVP---TTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTA 350
+ T F+KPTV V T GP LSVISIDHLPSLLPRE+SE FS LLPSL L RK A
Sbjct: 300 ITTTFDKPTVPVTLPAGTQGPPLSVISIDHLPSLLPRESSEMFSQALLPSLLQLKNRKDA 359
Query: 351 PVWVRAKKLFDRHCARVK 368
VW +A+ LF + A +
Sbjct: 360 RVWTQAEDLFKQKVATLP 377
>ref|XP_001593244.1| saccharopine dehydrogenase [Sclerotinia sclerotiorum 1980]
gb|EDO03685.1| saccharopine dehydrogenase [Sclerotinia sclerotiorum 1980]
Length = 372
Score = 414 bits (1064), Expect = e-114, Method: Composition-based stats.
Identities = 217/370 (58%), Positives = 266/370 (71%), Gaps = 2/370 (0%)
Query: 1 MAAVTLHLRAET-KPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIV 59
M+ TLHLR+E K LE R+ALTPTT K LI G+ I VE SP+ F+ E+ + GA +V
Sbjct: 1 MSGTTLHLRSELGKALEHRSALTPTTAKALIDAGYTINVERSPERIFDDEEFEKVGATLV 60
Query: 60 PAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
P +W+ AP+D IIIGLKE+P D FPL H H+QFAHCYK Q GW VL RF +G GTL
Sbjct: 61 PEDTWRQAPKDHIIIGLKELPVED-FPLEHVHVQFAHCYKQQGGWDTVLSRFPRGGGTLL 119
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
DLEFL +D+GRRVAAFG++AGFAGAAL + WA++ THS E P+VS YPNE L+ DV
Sbjct: 120 DLEFLTDDKGRRVAAFGYHAGFAGAALALETWAWQLTHSASEPFPSVSSYPNEDELIADV 179
Query: 180 TKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
K + P VL+IGALGRCGSGA+DL + G+P N+LKWD+ ET++GGPF E
Sbjct: 180 KKAIAAGQEKTGKAPRVLVIGALGRCGSGAVDLCLRAGVPTENVLKWDMAETAKGGPFPE 239
Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
I ++DIFINCIYL I F +M+ L+ PNR+L V DVSADTTNP+NPIPIYTVAT F+
Sbjct: 240 IVESDIFINCIYLMSKIPNFVDMQSLDTPNRKLSVVCDVSADTTNPNNPIPIYTVATTFS 299
Query: 300 KPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
+PTV V P+LSVISIDHLPSLLPREASE FS DLLPSL L ++ PVW +A+KL
Sbjct: 300 EPTVPVEVKGDPRLSVISIDHLPSLLPREASEAFSKDLLPSLLTLKDWRSTPVWAKAEKL 359
Query: 360 FDRHCARVKR 369
F A + +
Sbjct: 360 FQEKVATLPK 369
>ref|XP_001803532.1| hypothetical protein SNOG_13323 [Phaeosphaeria nodorum SN15]
gb|EAT79207.1| hypothetical protein SNOG_13323 [Phaeosphaeria nodorum SN15]
Length = 387
Score = 413 bits (1063), Expect = e-113, Method: Composition-based stats.
Identities = 212/382 (55%), Positives = 261/382 (68%), Gaps = 17/382 (4%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQ-----STFNINEYRQAG 55
M+ TLH RAE KPLE R+ALTPTT KKL+ G+ + VE SP+ F E+ QAG
Sbjct: 1 MSFPTLHARAEAKPLEHRSALTPTTAKKLLDAGYPVLVERSPKDPNYARIFKDEEFEQAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A ++ G++KTAP+DRIIIGLKE+PE + FPL H + FAHCYK Q GW+ VL RF +G
Sbjct: 61 ATLIEEGAYKTAPKDRIIIGLKELPEDE-FPLEHTFVHFAHCYKQQGGWEKVLARFPRGG 119
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
GTLYDLEFL++ GRRVAAFG++AGF GAAL ++ WA++ TH + E LP V
Sbjct: 120 GTLYDLEFLQDTTGRRVAAFGYHAGFVGAALAIKTWAWQLTHPNGEPLPGVETFTDGRGY 179
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE L+ + +D KP+ L++GALGRCGSGA+DLL K+G P+ I KWD+
Sbjct: 180 YNNESELITQLKEDVAAGEKVAGHKPSSLVLGALGRCGSGAVDLLEKIGCPE--IKKWDL 237
Query: 229 KETS-RGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHN 287
ET R GP+ EI ++DIF+NCIYLSKPI PF N E L +P R+L V DVS DTTNPHN
Sbjct: 238 PETKERDGPYPEIIESDIFVNCIYLSKPIPPFVNKESLKSPKRKLSVVCDVSCDTTNPHN 297
Query: 288 PIPIYTVATVFNKPTVLVPTT-AGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQ 346
PIPIY + T F+KPTV V GP+LSVISIDHLPS LPRE+SE FS+ LLPSL L
Sbjct: 298 PIPIYDINTTFDKPTVGVDVEGDGPRLSVISIDHLPSALPRESSEAFSNALLPSLMALKD 357
Query: 347 RKTAPVWVRAKKLFDRHCARVK 368
R T PVW A+KLF +
Sbjct: 358 RATTPVWQGAEKLFQEKVQTLP 379
>ref|NP_592972.1| saccharopine dehydrogenase [NAD+, L-lysine forming] (PMID 3142867)
[Schizosaccharomyces pombe]
sp|Q09694|LYS1_SCHPO Saccharopine dehydrogenase [NAD+, L-lysine-forming]
(Lysine--2-oxoglutarate reductase) (SDH)
emb|CAB61467.1| saccharopine dehydrogenase [NAD+, L-lysine forming] (PMID 3142867)
[Schizosaccharomyces pombe]
Length = 368
Score = 412 bits (1061), Expect = e-113, Method: Composition-based stats.
Identities = 212/369 (57%), Positives = 260/369 (70%), Gaps = 3/369 (0%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M A L LRAETKPLE R+ALTP T K L GF+I +E S Q F E+ + G +VP
Sbjct: 1 MVAPHLWLRAETKPLEERSALTPRTAKILADAGFQITIERSSQRAFKDKEFERLGFPMVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW+ AP+D IIGLKE+PE D PL H HIQFAHCYK+Q GW+ VL RF G+G LYD
Sbjct: 61 EGSWRHAPKDAYIIGLKELPENDNSPLKHTHIQFAHCYKNQEGWREVLSRFPAGNGLLYD 120
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL++D GRRVAAFG++AGFAG+A+ WA + H + + PA+ P+PNEK+LV+ V
Sbjct: 121 LEFLQDDNGRRVAAFGYHAGFAGSAISCLVWAHQLLHPN-KQFPAIRPFPNEKSLVRHVA 179
Query: 181 KDYKEALAT-GARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDE 239
+ + AL + P +L+IGALGRCG+GA DL K+GIP NIL+WDI ET +GGPF E
Sbjct: 180 RQVRLALKKNNNQYPRILVIGALGRCGTGACDLASKIGIPFDNILRWDINETKKGGPFTE 239
Query: 240 IPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFN 299
I ++DIF+NCIYLS PI F +E LN PNR+LR V DVS DTTNP+NPIPIY V T F+
Sbjct: 240 ITESDIFVNCIYLSMPIPKFCTVESLNVPNRKLRVVCDVSCDTTNPNNPIPIYNVNTTFD 299
Query: 300 KPTVLVPTT-AGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKK 358
PTV V P L VISIDHLP+LLPRE+SE FS L+PSL L APVWVRAKK
Sbjct: 300 HPTVEVKGVTTPPPLEVISIDHLPTLLPRESSEAFSEALIPSLLALKDVDNAPVWVRAKK 359
Query: 359 LFDRHCARV 367
L++ ++
Sbjct: 360 LYETMVQKL 368
>gb|EEH34800.1| saccharopine dehydrogenase [Paracoccidioides brasiliensis Pb01]
Length = 384
Score = 412 bits (1059), Expect = e-113, Method: Composition-based stats.
Identities = 200/384 (52%), Positives = 257/384 (66%), Gaps = 15/384 (3%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAG 55
M+ VTLHLRAE K LE R+ALTP T + L+ G+ + VE SP + F E+ +AG
Sbjct: 1 MSPVTLHLRAEDKILEHRSALTPATTRALVDAGYIVRVERSPTSALRKRIFPDAEFEEAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +VP GSW AP D II+GLKE+ ET FPL H H+ FAHCYK+Q GW+ L R+ +G+
Sbjct: 61 ATLVPEGSWVDAPLDSIILGLKELDETKDFPLRHAHVTFAHCYKNQGGWEKSLGRWSRGN 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAV-------SP 168
G LYDLEFL++D GRR+AAFG++AGFAGAAL ++ WA++ H D LP V
Sbjct: 121 GVLYDLEFLQDDNGRRIAAFGYHAGFAGAALALKTWAWQLEHPDGTPLPGVEQFTDGRGY 180
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE ++ + D R+P VLIIGALGRCG GA+D K G +IL+WD+
Sbjct: 181 YLNEAEMIGQIRNDVARGEKIATRRPRVLIIGALGRCGKGAVDACVKAG--CEDILRWDM 238
Query: 229 KETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNP 288
ET++GGPF EI ++DIF+NCIYLS+ IAPF +ME L +P+RRL + DVS DTTNP+NP
Sbjct: 239 AETAKGGPFQEIVESDIFVNCIYLSEKIAPFVDMESLKSPDRRLSVICDVSCDTTNPNNP 298
Query: 289 IPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRK 348
IPIY + T F KPTV +P + P LSVISIDHLPSLLP E+S FS DLLP ++ + R
Sbjct: 299 IPIYNINTTFGKPTVALPLSNPP-LSVISIDHLPSLLPAESSNAFSADLLPYMKEIKHRD 357
Query: 349 TAPVWVRAKKLFDRHCARVKRSSR 372
+ PVW RA+KLF + +
Sbjct: 358 SNPVWQRAEKLFRDKVKALPEELQ 381
>ref|XP_363433.1| hypothetical protein MGG_01359 [Magnaporthe grisea 70-15]
gb|EDK04946.1| hypothetical protein MGG_01359 [Magnaporthe grisea 70-15]
Length = 365
Score = 411 bits (1058), Expect = e-113, Method: Composition-based stats.
Identities = 213/369 (57%), Positives = 261/369 (70%), Gaps = 5/369 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M++ LHLR+ETKPLE R+ALTPTT K LI G+ + VE SP F+ E+ GA +VP
Sbjct: 1 MSS-ILHLRSETKPLEHRSALTPTTTKALIEAGYTVNVERSPVRIFDDAEFEAVGATLVP 59
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
GSW+ P+D I+IGLKE+ E FPL H HIQFAHCYK+Q GW VL R+ G G L D
Sbjct: 60 EGSWEQIPKDHIVIGLKEL-EEKDFPLKHTHIQFAHCYKNQGGWDKVLRRYHDGEGMLLD 118
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
+EFLE GRRVAAFG++AGFAGAAL +++WA++ T+S E LP+V PNE ALV D+
Sbjct: 119 IEFLEK-DGRRVAAFGYWAGFAGAALALQNWAWQLTNS-GEPLPSVESRPNEAALVGDIK 176
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
+ R P V++IGALGRCG GA+D+ K GIPD NILKWD++ET+ GGPF EI
Sbjct: 177 EALAGGKEKAGRLPRVIVIGALGRCGRGAVDMCKKAGIPDENILKWDMEETAPGGPFKEI 236
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
++DIF+NCIYL+K I PF ME LN P R+L + D SADTTNP NP+P+YTVAT F+K
Sbjct: 237 VESDIFVNCIYLNKQIPPFVTMESLNTPERKLSVINDCSADTTNPFNPVPVYTVATTFDK 296
Query: 301 PTVLVPT-TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKL 359
PTV V + GP LSVISIDHLPSLLPREASE FS+DLLP L L K+ PVW A+KL
Sbjct: 297 PTVPVDGLSHGPPLSVISIDHLPSLLPREASESFSNDLLPYLLKLKDWKSDPVWAGAEKL 356
Query: 360 FDRHCARVK 368
F +
Sbjct: 357 FHEKVKTLP 365
>gb|EDU47954.1| saccharopine dehydrogenase [Pyrenophora tritici-repentis Pt-1C-BFP]
Length = 387
Score = 409 bits (1053), Expect = e-112, Method: Composition-based stats.
Identities = 212/382 (55%), Positives = 262/382 (68%), Gaps = 17/382 (4%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQ-----STFNINEYRQAG 55
MA TLH RAE KPLE R+ LTPTT KKL+ G+ + VE SP+ F +E+ + G
Sbjct: 1 MAFPTLHARAEAKPLEHRSCLTPTTAKKLLDAGYPVLVERSPKDPNYARIFKDDEFEEVG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A ++ G++KTAP+DRIIIGLKE+PE FPL H + FAHCYK Q GW+NVL RF +G
Sbjct: 61 ATLIEEGAYKTAPKDRIIIGLKELPEDK-FPLEHTFVHFAHCYKQQGGWENVLARFPRGG 119
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSP------- 168
GTLYDLEFL+++ GRRVAAFG++AGF GAAL ++ WA++ TH + E LP +
Sbjct: 120 GTLYDLEFLQDESGRRVAAFGYHAGFVGAALAIKTWAWQLTHPNGEPLPGLETFTEGRGY 179
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE L+ + +D KP+ L++GALGRCGSGA+DLL K+G P+ I KWD+
Sbjct: 180 YNNESELITQLKEDVAAGEKIAGHKPSSLVLGALGRCGSGAVDLLEKIGCPE--IKKWDL 237
Query: 229 KETS-RGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHN 287
ET R GP+ EI ++DIF+NCIYLSKPI PF N E L +PNRRL V DVS DTTNPHN
Sbjct: 238 AETKERDGPYPEIVESDIFVNCIYLSKPIPPFVNKESLKSPNRRLSVVCDVSCDTTNPHN 297
Query: 288 PIPIYTVATVFNKPTVLVPTT-AGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQ 346
PIPIY + T F+KPTV V GP+LSVISIDHLPS LPRE+SE FS+ LLPSL L
Sbjct: 298 PIPIYDINTTFDKPTVEVSVEGDGPRLSVISIDHLPSALPRESSEAFSNALLPSLMALKD 357
Query: 347 RKTAPVWVRAKKLFDRHCARVK 368
R T PVW A+KLF +
Sbjct: 358 RATTPVWQGAEKLFQEKVQTLP 379
>ref|XP_001220083.1| hypothetical protein CHGG_00862 [Chaetomium globosum CBS 148.51]
gb|EAQ92627.1| hypothetical protein CHGG_00862 [Chaetomium globosum CBS 148.51]
Length = 375
Score = 407 bits (1046), Expect = e-112, Method: Composition-based stats.
Identities = 214/375 (57%), Positives = 259/375 (69%), Gaps = 7/375 (1%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
MA LHLR+ETKPLE R+ALTPTT LI G+ + VE SP F+ E+ AGA +VP
Sbjct: 1 MAPTVLHLRSETKPLEHRSALTPTTTAALIKAGYTVNVERSPVRIFDDAEFEAAGATLVP 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
SW AP++ IIIGLKE+ E FPL H H+QFAHCYK Q GW+ VL RF +G GTL D
Sbjct: 61 EYSWVDAPKEHIIIGLKEL-EEKEFPLKHVHVQFAHCYKQQGGWETVLARFPRGGGTLLD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL ++ GRRVAAFG++AGFAGAAL + W+++ H E P V YPNE ALV +V
Sbjct: 120 LEFLVDENGRRVAAFGYHAGFAGAALALEVWSWQLNH--SEPFPGVESYPNEDALVSNVK 177
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K + R P V++IGALGRCGSGA++ L K G+P+ NILKWD+ ET+ GGPF EI
Sbjct: 178 KALASGIEKAGRSPRVIVIGALGRCGSGAVEALRKAGVPEENILKWDMAETAGGGPFKEI 237
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSA---DTTNPHNPIPIYTVATV 297
+DIF+NCIYL+K I F N+E L P+R+L V DVSA DTT+P P+PIYTVAT
Sbjct: 238 TDSDIFVNCIYLTKKIPNFVNLESLQVPDRKLSVVCDVSAASQDTTSPFTPVPIYTVATT 297
Query: 298 FNKPTVLVPT-TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRA 356
F++PTV V +GP LSVISIDHLPSLLPREASE FS DLLPSL L + PVW RA
Sbjct: 298 FDEPTVAVEGLQSGPALSVISIDHLPSLLPREASEAFSQDLLPSLLALNDWQNTPVWSRA 357
Query: 357 KKLFDRHCARVKRSS 371
KLF A + S+
Sbjct: 358 DKLFKEKVATLPASA 372
>ref|XP_001745712.1| predicted protein [Monosiga brevicollis MX1]
gb|EDQ89683.1| predicted protein [Monosiga brevicollis MX1]
Length = 499
Score = 403 bits (1037), Expect = e-110, Method: Composition-based stats.
Identities = 177/367 (48%), Positives = 236/367 (64%), Gaps = 7/367 (1%)
Query: 4 VTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP----QSTFNINEYRQAGAIIV 59
+ L LR+E K E R ALTP K+L+ +G+ I VE SP + + ++Y G +
Sbjct: 131 MHLWLRSEVKANEHRTALTPEACKELLGEGYTITVERSPEASTKRIYEDSDYEAVGCQLA 190
Query: 60 PAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLY 119
+ SW +AP+D II+GLKE+PE PL H H+ F HCYK+Q GW+++L RF G+G+L
Sbjct: 191 ESQSWPSAPKDAIIVGLKELPEDG-SPLEHTHLYFGHCYKNQGGWKDLLKRFHAGNGSLL 249
Query: 120 DLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDV 179
D+EFL NDQGRRVAAFG+ AGFAG+ + W ++ D + A+S YPNE L+K
Sbjct: 250 DMEFLTNDQGRRVAAFGYMAGFAGSFSALDVWCHRKLEGD-KPYGALSAYPNEDELLKYS 308
Query: 180 TKDYKEALATG-ARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFD 238
+ A A R P VL+IGALGRCG+GA D + GIP+AN+L+WD+ ET GGPF+
Sbjct: 309 RARIEAAAAKNDGRLPRVLVIGALGRCGNGACDFATRAGIPEANVLRWDMAETKVGGPFN 368
Query: 239 EIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVF 298
E+ DIF+NCIYLS+PI PF L +R L V DVS DT+NPHNPIP +T F
Sbjct: 369 ELLDVDIFVNCIYLSQPIPPFITEAMLEKEDRALSVVCDVSCDTSNPHNPIPFANKSTTF 428
Query: 299 NKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKK 358
++PT V G + VI+IDHLP+LLP+E+S+ + HDLLPS+ L + PVW RA K
Sbjct: 429 DEPTYQVKPKVGGPVDVITIDHLPTLLPKESSDRYCHDLLPSIRELKNMDSNPVWQRAIK 488
Query: 359 LFDRHCA 365
LF+ A
Sbjct: 489 LFEEKKA 495
>emb|CAX65448.1| putative saccharopine dehydrogenase (NAD+,L-lysine-forming)
[Gibberella fujikuroi]
Length = 390
Score = 389 bits (999), Expect = e-106, Method: Composition-based stats.
Identities = 191/384 (49%), Positives = 239/384 (62%), Gaps = 17/384 (4%)
Query: 4 VTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAGAII 58
+ LRAE KPLE R + +P +K L+ G+ I VE S + F +EY AGA +
Sbjct: 5 PHILLRAEEKPLEHR-SFSPAIIKTLVDAGYPISVERSSTDPKFKRIFEDSEYEAAGARL 63
Query: 59 VPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTL 118
V G W A II+GLKE+P D FPL ++HI FAHCYK+Q GW+ VL R+ +G L
Sbjct: 64 VDTGVWPNAEPGTIILGLKELPSED-FPLKNDHITFAHCYKNQGGWEQVLGRWARGGSRL 122
Query: 119 YDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLP------AVSPYPNE 172
YDLEFL ++QGRRV+AFG++AGFAGAALG++ A + S + Y NE
Sbjct: 123 YDLEFLVDEQGRRVSAFGYHAGFAGAALGIKTLAHQLQGSSSKLPSVETFTDGRGYYLNE 182
Query: 173 KALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETS 232
LV + +D +A RKPT L++GALGRCG GA+DL K G+PD NI +WD+ ET
Sbjct: 183 DELVNQIREDLAKAEKALGRKPTALVLGALGRCGKGAVDLFLKAGMPDDNITRWDLNETK 242
Query: 233 -RGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPI 291
R GP++EI +AD+F+N IYLSKPI PF N E L R L V+DVS DTTNPHNPIPI
Sbjct: 243 DRDGPYEEIAKADVFLNAIYLSKPIPPFINQELLAKQGRNLAVVIDVSCDTTNPHNPIPI 302
Query: 292 YTVATVFNKPTVLVPTTAGP---KLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRK 348
Y++ T F PTV V LSVISIDHLPS+LPREASE FS L SL L R+
Sbjct: 303 YSINTTFEDPTVPVEIKDDQNNLPLSVISIDHLPSMLPREASEAFSEGLKESLLTLKDRE 362
Query: 349 TAPVWVRAKKLFDRHCARVKRSSR 372
T+ VW A+KLF A + R
Sbjct: 363 TSRVWTDAEKLFHEKVALLPEELR 386
>ref|XP_001544099.1| saccharopine dehydrogenase [Ajellomyces capsulatus NAm1]
gb|EDN03281.1| saccharopine dehydrogenase [Ajellomyces capsulatus NAm1]
Length = 376
Score = 385 bits (990), Expect = e-105, Method: Composition-based stats.
Identities = 191/383 (49%), Positives = 249/383 (65%), Gaps = 21/383 (5%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAG 55
MA VTLHLR E K LE R+ALTP T + L+ G+ + +E SP + F E+ +AG
Sbjct: 1 MAPVTLHLRTEDKILEHRSALTPQTTRLLVDAGYIVNIERSPTSALRKRIFPDAEFEKAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +VP GSW AP D II+GLKE+ ET FPL H H+ FAHCYK Q GW+ L R+ +G+
Sbjct: 61 ATLVPEGSWVDAPLDHIILGLKELDETKDFPLRHAHVTFAHCYKGQGGWEKALGRWSRGN 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLP------AVSPY 169
G LYDLEFL++D GRR+AAFG++AGFAGAAL ++ WA++ H D Y
Sbjct: 121 GVLYDLEFLQDDIGRRIAAFGYHAGFAGAALALKTWAWQLQHPDTPLPSVDHFTDGRGYY 180
Query: 170 PNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIK 229
NEK +V + +D KP VL+IGALGRCG GA+D K G ++L+WD+
Sbjct: 181 LNEKEMVDQIREDVIRGEKIAGHKPRVLVIGALGRCGRGAVDACVKAG--CEDVLRWDMA 238
Query: 230 ETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPI 289
ET++GGPF EI ++DIF+NCIYL++ I PF +ME L +PNR+L V DVS DTTNP+NPI
Sbjct: 239 ETAKGGPFQEIVESDIFVNCIYLNEKIPPFVDMESLKSPNRKLSVVCDVSCDTTNPNNPI 298
Query: 290 PIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKT 349
F+KPTV +P + P LSVISIDHLPSLLP E+S+ FS DLLP + + R +
Sbjct: 299 -------TFDKPTVPLPLSNPP-LSVISIDHLPSLLPAESSDAFSTDLLPCMMEIKNRAS 350
Query: 350 APVWVRAKKLFDRHCARVKRSSR 372
PVW RA+KLF + + +
Sbjct: 351 HPVWQRAEKLFREKVKTLPEALQ 373
>ref|XP_001873276.1| predicted protein [Laccaria bicolor S238N-H82]
gb|EDR15068.1| predicted protein [Laccaria bicolor S238N-H82]
Length = 367
Score = 377 bits (969), Expect = e-103, Method: Composition-based stats.
Identities = 195/373 (52%), Positives = 237/373 (63%), Gaps = 11/373 (2%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M+ L LR E K E RAALTPTT KLIA GF I+VE Q F+ +EY G +V
Sbjct: 1 MSKPILWLRCEKKEFERRAALTPTTSSKLIAAGFDIFVERDEQRIFDDSEYEAVGCTLVD 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
SW TA IIGLKE+PE+ T PL H HIQFAHCYK QAGW VL RF +G GTLYD
Sbjct: 61 NNSWPTARTSTPIIGLKELPES-TDPLPHTHIQFAHCYKQQAGWSKVLSRFHRGGGTLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL++ GRRVAAFGF AG A +L ++PY NE+A+V +V
Sbjct: 120 LEFLQDANGRRVAAFGF---HAGFAGAAAGALALAAQRGGNELGLLTPYANEEAMVNNVK 176
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
+ + L+IGALGRCG GA+DL K+G+ + +ILKWD++ET++GGPF +I
Sbjct: 177 E--LLGG--SGKGVRALVIGALGRCGRGAVDLFRKIGLDEDDILKWDLEETAKGGPFSKI 232
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPN--RRLRTVVDVSADTTNPHNPIPIYTVATVF 298
DIF+NCIYL+ I F E++ RRL VVDVS DTTNP NPIPIY + T F
Sbjct: 233 LDVDIFVNCIYLTSQIPSFVTREQVIAAGKDRRLSVVVDVSCDTTNPFNPIPIYNINTTF 292
Query: 299 NKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKK 358
+KPTV V P LSVISIDHLP+LLPREASE FS DLLPSL P+R+T+ VW AK+
Sbjct: 293 DKPTVPVDVGGLPALSVISIDHLPTLLPREASEQFSSDLLPSLLEFPERETSRVWADAKR 352
Query: 359 LF-DRHCARVKRS 370
LF ++ VK
Sbjct: 353 LFLEKKVEAVKAE 365
>ref|YP_612102.1| alanine dehydrogenase/PNT-like [Silicibacter sp. TM1040]
gb|ABF62840.1| saccharopine dehydrogenase (NAD+, L-lysine-forming) [Silicibacter
sp. TM1040]
Length = 350
Score = 375 bits (964), Expect = e-102, Method: Composition-based stats.
Identities = 155/363 (42%), Positives = 211/363 (58%), Gaps = 14/363 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE + E R LTP K L+ G ++ VE+S + Y AG I P
Sbjct: 1 MTHLWVRAEQRLNEDRVGLTPAGAKALLEAGIRVTVEESSSRAIPLQGYIDAGCEIAPEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
+W APRD II GLKE+P+ T PL H HI F H +K Q + +L RF +G GTLYDLE
Sbjct: 61 AWPDAPRDAIIFGLKELPDDGT-PLPHRHIMFGHAFKGQHSGKELLRRFREGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L + GRRVAAFG++AG+AGAA+ ++ WA +Q E V Y N+ AL+ D+ ++
Sbjct: 120 YLVDPSGRRVAAFGYWAGYAGAAVTLKAWAAQQR---GETCGPVGVYKNKDALLADLGRE 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
TGA +P ++IGALGR G+GA DL +G + KWD+ ET+ GGPF EI
Sbjct: 177 LDA---TGADRPKAIVIGALGRVGTGAADLCEAMG---VAVTKWDMNETASGGPFPEILD 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
D+F+NCI+ F E L R L + DV+ D + +NP+P+Y+ AT ++ P
Sbjct: 231 HDLFLNCIFARPGTPVFVPKEALTAA-RNLTAIGDVACDPDSDYNPVPVYSRATTWDAPV 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V V P L V++ID+LPS+LP E+SE ++ LL SL L A VW RAK +FD
Sbjct: 290 VRVAND--PVLDVMAIDNLPSMLPAESSEDYADQLLASLLTLSDLD-AGVWGRAKAVFDE 346
Query: 363 HCA 365
H A
Sbjct: 347 HVA 349
>ref|XP_391101.1| hypothetical protein FG10925.1 [Gibberella zeae PH-1]
Length = 383
Score = 371 bits (953), Expect = e-101, Method: Composition-based stats.
Identities = 189/388 (48%), Positives = 242/388 (62%), Gaps = 25/388 (6%)
Query: 1 MAA-VTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQA 54
M+ + LRAE KPLE R + +P+ +K L+ G+ + VE S + F +EY A
Sbjct: 1 MSQYPHILLRAEEKPLEHR-SFSPSIIKTLVDAGYPVSVERSSTDPKFKRIFEDSEYEAA 59
Query: 55 GAIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKG 114
GA +V G+W A +I+GLKE+PE D FPL ++HI +Q GW+ VL RF +G
Sbjct: 60 GARLVNEGTWPNAEAGTLILGLKEIPEED-FPLKNDHI-------NQGGWEKVLGRFPQG 111
Query: 115 HGTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLP------AVSP 168
LYDLEFL ++QGRRV+AFGF+AGFAGAALG++ A + +
Sbjct: 112 SSVLYDLEFLVDEQGRRVSAFGFHAGFAGAALGIKTLAHQLQDPSSKLPSVETFTDGRGY 171
Query: 169 YPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDI 228
Y NE+ LV + +D +A + RKPT L++GALGRCG GA+DL K G+PD NI +WD+
Sbjct: 172 YLNEEELVNQIREDLAKAEKSLGRKPTALVLGALGRCGKGAVDLFLKAGMPDENITRWDL 231
Query: 229 KETS-RGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHN 287
ET R GP++EI QAD+F+N IYLSKPI PF N E L R L V+DVS DTTNPHN
Sbjct: 232 NETKDRDGPYEEIAQADVFLNAIYLSKPIPPFINEELLAKSGRNLAVVIDVSCDTTNPHN 291
Query: 288 PIPIYTVATVFNKPTVLVPTTAGP---KLSVISIDHLPSLLPREASEFFSHDLLPSLELL 344
PIPIY++ T F +PTV V LSVISIDHLPS+LPREASE FS L SL L
Sbjct: 292 PIPIYSINTTFEEPTVPVEIKNDQNSLPLSVISIDHLPSMLPREASEAFSEGLKESLLTL 351
Query: 345 PQRKTAPVWVRAKKLFDRHCARVKRSSR 372
RKT+ VW A+KLF+ A + S R
Sbjct: 352 KDRKTSRVWADAEKLFNEKVALLPESLR 379
>ref|XP_570078.1| saccharopine dehydrogenase (NAD+, L-lysine-forming) [Cryptococcus
neoformans var. neoformans JEC21]
ref|XP_776193.1| hypothetical protein CNBD0140 [Cryptococcus neoformans var.
neoformans B-3501A]
gb|EAL21546.1| hypothetical protein CNBD0140 [Cryptococcus neoformans var.
neoformans B-3501A]
gb|AAW42771.1| saccharopine dehydrogenase (NAD+, L-lysine-forming), putative
[Cryptococcus neoformans var. neoformans JEC21]
Length = 395
Score = 371 bits (953), Expect = e-101, Method: Composition-based stats.
Identities = 209/368 (56%), Positives = 252/368 (68%), Gaps = 6/368 (1%)
Query: 6 LHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWK 65
+ LR E KP E R+ALTPTT K L+ F +YVE PQ F+ E+ G IVP +W
Sbjct: 21 IWLRCEKKPFEHRSALTPTTAKTLLDSNFDVYVEKDPQRIFDDREFEAVGCKIVPHNTWP 80
Query: 66 TAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLE 125
+AP D IIGLKE+PE+ T PL H HIQFAHCYK QAGW +VL RF +G GTLYDLEFLE
Sbjct: 81 SAPVDVPIIGLKELPES-TDPLPHTHIQFAHCYKQQAGWNDVLRRFAQGKGTLYDLEFLE 139
Query: 126 ND-QGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYK 184
+ RRVAAFGF+AGFAGAA G +A +QT + L + PYPNE +VK+V+ +
Sbjct: 140 DPVSHRRVAAFGFHAGFAGAAAGALAFAAQQTQNGQGKLGELKPYPNEGEMVKEVS-EAL 198
Query: 185 EALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQAD 244
+ G + VLIIGALGRCGSGA+DL K G+ + NI+KWD+ ET++GGPF EI D
Sbjct: 199 QGTKEGNKGVKVLIIGALGRCGSGAVDLFRKAGVAEENIIKWDMAETAKGGPFPEILDVD 258
Query: 245 IFINCIYLSKPIAPFTNMEKLNNPN--RRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
IF+NCIYLSKPI F E + RRL VVDVS DTTNPHNPIPIY++ T F PT
Sbjct: 259 IFVNCIYLSKPIPKFITSEFIAEAGADRRLSVVVDVSCDTTNPHNPIPIYSINTTFPSPT 318
Query: 303 VLVPTT-AGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFD 361
V V T G + +VISIDHLP+LLPREASE FS DLLPSL LP+R+TA VWV A+KLF
Sbjct: 319 VEVDTKGVGKRCTVISIDHLPTLLPREASEQFSTDLLPSLLQLPERQTAEVWVNAEKLFR 378
Query: 362 RHCARVKR 369
++
Sbjct: 379 TKLEEARK 386
>ref|XP_001828899.1| hypothetical protein CC1G_03693 [Coprinopsis cinerea okayama7#130]
gb|EAU92906.1| hypothetical protein CC1G_03693 [Coprinopsis cinerea okayama7#130]
Length = 369
Score = 371 bits (953), Expect = e-101, Method: Composition-based stats.
Identities = 204/363 (56%), Positives = 238/363 (65%), Gaps = 11/363 (3%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M+ TL LR E K E RAALTPTT KKLI GF I+VE Q F+ +EY AG +V
Sbjct: 1 MSKPTLWLRCEKKEFERRAALTPTTAKKLIEAGFDIFVEKDEQRIFDDSEYEAAGCKLVE 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
+W +AP+D IIGLKE+P +D PL H HIQFAHCYK Q GW VL RF KG GTLYD
Sbjct: 61 NNTWASAPKDVPIIGLKELPVSDE-PLPHTHIQFAHCYKKQGGWSQVLARFYKGGGTLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LEFL ++ GRRVAAFGF+AG A +DL ++PYPNE A+V DV
Sbjct: 120 LEFLNDENGRRVAAFGFHAG---FAGAAAGALAVAARRQGKDLGLLTPYPNEAAMVDDVK 176
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
K +L + L+IGALGRCG GA+DL K+G+ + +ILKWD+ ET++GGPF EI
Sbjct: 177 K----SLGGSGKGLKALVIGALGRCGRGAVDLFRKIGLEENDILKWDMAETAKGGPFPEI 232
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPN--RRLRTVVDVSADTTNPHNPIPIYTVATVF 298
DIF+NCIYLS I F E RRL VVDVS DTTNP+NPIPIY + T F
Sbjct: 233 LDVDIFVNCIYLSSQIPSFITKETAIAAGKDRRLSVVVDVSCDTTNPYNPIPIYNINTTF 292
Query: 299 NKPTVLVPT-TAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAK 357
+KPTV V P LSVISIDHLP+LLPREASE FS DLLPSL PQR TA VWV A+
Sbjct: 293 DKPTVAVDVGAENPPLSVISIDHLPTLLPREASEQFSGDLLPSLLEFPQRSTARVWVEAE 352
Query: 358 KLF 360
KLF
Sbjct: 353 KLF 355
>gb|EEH50065.1| saccharopine dehydrogenase [Paracoccidioides brasiliensis Pb18]
Length = 377
Score = 370 bits (951), Expect = e-100, Method: Composition-based stats.
Identities = 184/388 (47%), Positives = 241/388 (62%), Gaps = 30/388 (7%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSP-----QSTFNINEYRQAG 55
M+ VTLHLRAE K LE R+ALTP T + L+ G+ + VE SP + F E+ +AG
Sbjct: 1 MSPVTLHLRAEDKILEHRSALTPATTRALVDAGYIVKVERSPTSALRKRIFPDAEFEEAG 60
Query: 56 AIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGH 115
A +VP GSW AP D II+GLKE+ ET FPL H H+ FAHCYK+Q GW+ L R+ +G+
Sbjct: 61 ATLVPEGSWVDAPLDSIILGLKELDETKDFPLRHAHVTFAHCYKNQGGWEKSLGRWSRGN 120
Query: 116 GTLYDLEFLENDQGRRVAAFGFYAGF----AGAALGVRDWAFKQTHSDDEDLPAV----- 166
G LYDLEFL+ + G + G+ AGAAL ++ W ++ H D LP V
Sbjct: 121 GVLYDLEFLQ----VSLIIIGQFGGYHAGFAGAALALKTWVWQLEHPDGTPLPGVEQFTD 176
Query: 167 --SPYPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANIL 224
Y NE ++ + D R+P +L+IGALGRCG GA+D K G +IL
Sbjct: 177 GRGYYLNEAEMISQIRNDVARGEKIATRRPRILVIGALGRCGKGAVDACVKAG--CEDIL 234
Query: 225 KWDIKETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTN 284
+WD+ ET++GGPF EI ++D+F+NCIYLS+ IAPF +ME L +PNRRL + DVS DTTN
Sbjct: 235 RWDMAETAKGGPFQEIVESDVFVNCIYLSEKIAPFIDMESLKSPNRRLSVICDVSCDTTN 294
Query: 285 PHNPIPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELL 344
P+NPI F KPTV +P + P LSVISIDHLPSLLP E+S FS DLLP ++ +
Sbjct: 295 PNNPI-------TFGKPTVALPLSNPP-LSVISIDHLPSLLPAESSNAFSADLLPYMKEI 346
Query: 345 PQRKTAPVWVRAKKLFDRHCARVKRSSR 372
R + PVW RA+KLF + +
Sbjct: 347 RHRDSNPVWQRAEKLFRDKVKALPEELQ 374
>ref|ZP_01753990.1| saccharopine dehydrogenase, putative [Roseobacter sp. SK209-2-6]
gb|EBA17471.1| saccharopine dehydrogenase, putative [Roseobacter sp. SK209-2-6]
Length = 352
Score = 369 bits (948), Expect = e-100, Method: Composition-based stats.
Identities = 147/364 (40%), Positives = 200/364 (54%), Gaps = 14/364 (3%)
Query: 1 MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP 60
M L +RAE +P E R LTP K L+ G ++ VE S + Y AG +
Sbjct: 1 MTMTHLWVRAEQRPNEDRVGLTPEGAKALLDAGLRVTVEKSSVRAIPMQGYIDAGCEVAA 60
Query: 61 AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD 120
SW AP D II GLKE+PE T PL H HI F H +K Q + +L RF G GTLYD
Sbjct: 61 ENSWPKAPADAIIFGLKELPEDGT-PLPHRHIMFGHAFKGQHSGKALLDRFQAGGGTLYD 119
Query: 121 LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT 180
LE+L + GRRVAAFG++AG+AGAA+ ++ W +Q E V Y + AL+ D+
Sbjct: 120 LEYLVEENGRRVAAFGYWAGYAGAAVTLKTWMAQQR---GELCGPVGVYSGKDALLADLG 176
Query: 181 KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI 240
+ A KP ++IGALGR G+GA DL +G + KWD+ ETS GGPF EI
Sbjct: 177 AELDALDA---EKPKAIVIGALGRVGTGAADLCEAMG---VAVTKWDMAETSSGGPFPEI 230
Query: 241 PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK 300
+ D+F+NCI+ F + L R L + DV+ D + +NP+P+Y AT ++
Sbjct: 231 LEHDLFLNCIFARPGTPVFVPQDALGTA-RNLSAIGDVACDPDSDYNPVPVYDRATTWDA 289
Query: 301 PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF 360
P + V P L V++ID+LPS+LP E+S ++ LLPSL L + VW RA+ F
Sbjct: 290 PALRVA--EDPVLDVMAIDNLPSMLPVESSIDYAEQLLPSLLTLTDL-KSGVWGRAEATF 346
Query: 361 DRHC 364
Sbjct: 347 REFV 350
>ref|ZP_00630414.1| Alanine dehydrogenase/PNT, C-terminal:Alanine dehydrogenase/PNT,
N-terminal [Paracoccus denitrificans PD1222]
ref|YP_916489.1| alanine dehydrogenase/PNT domain protein [Paracoccus denitrificans
PD1222]
gb|ABL70793.1| saccharopine dehydrogenase (NAD+, L-lysine-forming) [Paracoccus
denitrificans PD1222]
Length = 351
Score = 366 bits (941), Expect = 1e-99, Method: Composition-based stats.
Identities = 150/365 (41%), Positives = 215/365 (58%), Gaps = 14/365 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
V L +R E++ E R +TP V++LIA+GF + VE+SP I +Y AGA I P G
Sbjct: 1 MVHLWVRTESRANERRVGITPAGVRELIAQGFHVTVEESPHRILPIADYAAAGAEIAPEG 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
+W AP + +I GLKE+PE T PL H HI F H YK Q +L RF +G GTLYDLE
Sbjct: 61 AWPGAPAEAVIFGLKELPEDGT-PLSHRHIMFGHAYKGQPAGLALLRRFREGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L + GRR+AAFG++AGFAGAA+ ++ WA ++ V+ +P+++A+ ++ +
Sbjct: 120 YLTDSDGRRLAAFGYWAGFAGAAVTLKAWATQRQ---GGICAPVAGWPSQEAMQDELRAE 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
A +P ++IGALGR G GA DLL +G + KWD+ ET+ GGPF EI
Sbjct: 177 LDATGAP---RPHAIVIGALGRVGGGASDLLAAMG---VRVTKWDMAETASGGPFPEILA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
++FINCI F E +P RRLR + DV+ D ++ NP+ +Y AT + +P
Sbjct: 231 HELFINCILAGPRTPVFVPPE-AVDPGRRLRVIGDVACDPSSDFNPVKVYDRATNWAEPV 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V P L V++ID+LPSLLPRE++ ++ LLP L+ L R W RA+ F
Sbjct: 290 IRVA--DHPPLDVMAIDNLPSLLPRESALDYAGQLLPVLKGL-DRIDEGAWGRARATFQD 346
Query: 363 HCARV 367
H + +
Sbjct: 347 HLSAL 351
>ref|ZP_01034544.1| saccharopine dehydrogenase, putative [Roseovarius sp. 217]
gb|EAQ27225.1| saccharopine dehydrogenase, putative [Roseovarius sp. 217]
Length = 351
Score = 365 bits (939), Expect = 2e-99, Method: Composition-based stats.
Identities = 152/362 (41%), Positives = 203/362 (56%), Gaps = 14/362 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE +P E R LTP +LI KG ++ VE+S I YR AG I
Sbjct: 1 MTHLWVRAEQRPNEERVGLTPEGAAQLITKGIRVTVEESHNRAIPIESYRAAGCEIATEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW +AP + II GLKE+PE DT PL H HI F H +K Q + +L RF GTLYDLE
Sbjct: 61 SWPSAPTEAIIFGLKELPEDDT-PLPHRHIMFGHAFKGQHAGRRLLQRFKARGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L ++ GRRVAAFG++AG+AGAA+ + W +Q P V YP AL+ D+
Sbjct: 120 YLVDETGRRVAAFGYWAGYAGAAVSLMAWTAQQ---GGAICPPVDTYPGRDALLADLGAQ 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
TGA +P ++IGALGR G+GA DL + D + +WD+ ET+ GGPF EI
Sbjct: 177 LDA---TGASRPRAIVIGALGRVGTGAADLCEAM---DVTVTRWDMAETASGGPFPEILA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
DIF+NCI+ F L+ P R+L + DV+ D + +NP+P+Y AT + P
Sbjct: 231 HDIFLNCIFARPGTPVFVPKSALDQP-RQLTVIGDVACDPDSDYNPVPVYDAATSWAAPV 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V P L V++ID+LPSLLP E+S ++ LL SL L VW RA + F
Sbjct: 290 LRVH--DAPPLDVMAIDNLPSLLPVESSRDYAGQLLASLLTLDTLDQ-GVWGRAAETFHT 346
Query: 363 HC 364
H
Sbjct: 347 HM 348
>ref|ZP_01901689.1| saccharopine dehydrogenase, putative [Roseobacter sp. AzwK-3b]
gb|EDM73387.1| saccharopine dehydrogenase, putative [Roseobacter sp. AzwK-3b]
Length = 353
Score = 362 bits (929), Expect = 3e-98, Method: Composition-based stats.
Identities = 160/367 (43%), Positives = 213/367 (58%), Gaps = 14/367 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L LRAE + E R LTP LIA+G + VEDS I YR AG I P
Sbjct: 1 MTHLWLRAEQRANEDRTGLTPEGAAALIARGLTVTVEDSRTRILPIEAYRAAGCAIAPEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
+W APRD II GLKE+P+ T PL H HI F H +K Q + +L RF G GTLYDLE
Sbjct: 61 AWPDAPRDAIIFGLKELPDDGT-PLPHRHIMFGHAFKGQHAGRRLLERFKAGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L + +GRRVAAFG++AG+AGAA+ + WA ++ P VS + ++ AL+ D+
Sbjct: 120 YLVDPEGRRVAAFGYWAGYAGAAISLMAWAAQRQ---GGLCPPVSAFADKDALLADL--- 173
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
ATG ++P+ ++IGALGR G+GA DL +GI +WD+ ET+ GGPF EI
Sbjct: 174 GARLDATGTKRPSAIVIGALGRVGTGAADLCTAMGI---TPTRWDMAETAHGGPFPEILA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
DIF+NCI+ F E L +R L + DV+ D + +NP+P+Y AT ++ P
Sbjct: 231 HDIFLNCIFARPGTPVFVPREALTQ-DRHLTVIGDVACDPDSDYNPVPVYASATTWDAPV 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V T P L V++ID+LPSLLP E+S ++ LLPSL L A VW RAK FD+
Sbjct: 290 TRVHDT--PPLDVMAIDNLPSLLPLESSLDYAAQLLPSLLTL-DALDAGVWGRAKATFDQ 346
Query: 363 HCARVKR 369
H V+
Sbjct: 347 HMKEVRA 353
>ref|YP_168503.1| saccharopine dehydrogenase, putative [Silicibacter pomeroyi DSS-3]
gb|AAV96534.1| saccharopine dehydrogenase, putative [Silicibacter pomeroyi DSS-3]
Length = 350
Score = 359 bits (922), Expect = 2e-97, Method: Composition-based stats.
Identities = 153/362 (42%), Positives = 205/362 (56%), Gaps = 14/362 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE +P E R LTP LIA G ++ VE+S ++ YR AG I P
Sbjct: 1 MTHLWVRAEQRPNEERVGLTPEGAAALIAAGLRVTVEESSVRAIPLDGYRDAGCQIAPEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW AP D II GLKE+PE T PL H HI F H +K Q + +L RF G GTLYDLE
Sbjct: 61 SWPDAPGDAIIFGLKELPEDGT-PLPHRHIMFGHAFKGQHSGRRLLERFKAGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L ++ GRRVAAFG++AG+AGAA+ ++ WA +Q V YP + L + +
Sbjct: 120 YLVDENGRRVAAFGYWAGYAGAAVTLKAWAAQQQ---GGICGPVGVYPGKDTLNAALAAE 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
A +P ++IGALGR G+GA DL +G + KWD+ ET+ GGPF EI
Sbjct: 177 LDATGAP---RPRAIVIGALGRVGTGAADLCTAMG---VEVTKWDMAETASGGPFPEILA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
DIF+NCI+ F E L+ P R L + DV+ D + +NP+P+Y AT ++ P
Sbjct: 231 HDIFLNCIFARPGTPVFVPREALSAP-RALTAIGDVACDPDSDYNPVPVYDRATSWDAPV 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V P L V++ID+LPS+LP E+SE ++ LLPSL L A VW RA+ F
Sbjct: 290 LRVA--EAPVLDVMAIDNLPSMLPVESSEDYAAQLLPSLLTLTDLD-AGVWGRARATFLG 346
Query: 363 HC 364
H
Sbjct: 347 HV 348
>ref|ZP_01442866.1| saccharopine dehydrogenase, putative [Roseovarius sp. HTCC2601]
gb|EAU47008.1| saccharopine dehydrogenase, putative [Roseovarius sp. HTCC2601]
Length = 351
Score = 359 bits (921), Expect = 3e-97, Method: Composition-based stats.
Identities = 145/365 (39%), Positives = 202/365 (55%), Gaps = 14/365 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE +P E R +TP LIA+G ++ VEDS YR+AGA I G
Sbjct: 1 MTHLWVRAEQRPNEERVGITPDGAAALIAQGMRVTVEDSATRIIPTQAYREAGAEIASEG 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW AP D ++ GLKE+PE T PL H HI F H YK Q Q +L RF G GTLYDLE
Sbjct: 61 SWPEAPDDALVFGLKELPEDGT-PLKHRHIMFGHAYKGQPAGQVLLQRFAAGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L + GRRVAAFG++AG+AGAA+ + WA +Q VS + + +A+ +++
Sbjct: 120 YLVDPDGRRVAAFGYWAGYAGAAVSLYAWAAQQ---GGAVCAPVSTWGDAEAMEAELSA- 175
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
GA +P ++IGALGR G+GA DL K+G + +WD+ ET+ GGPF E+
Sbjct: 176 --ALAEAGAARPRAIVIGALGRVGTGASDLCEKMG---VAVTRWDMAETAHGGPFPEVLD 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
+F+NCI F R+L + D++ D + +P+ +Y AT + P
Sbjct: 231 HALFLNCILARPGTPVFV-PASAPTDPRKLAVIGDIACDPDSDFSPVKVYDRATSWEAPV 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V T P L V++ID+LPSLLP E+S F+ LLP L+ L A VW RA+ F+
Sbjct: 290 LRVHDT--PALDVMAIDNLPSLLPLESSHDFAGQLLPWLKQLGALD-AGVWGRAEDTFNT 346
Query: 363 HCARV 367
+
Sbjct: 347 YKPEA 351
>ref|YP_001044623.1| alanine dehydrogenase/PNT domain protein [Rhodobacter sphaeroides
ATCC 17029]
gb|ABN77851.1| saccharopine dehydrogenase (NAD+, L-lysine-forming) [Rhodobacter
sphaeroides ATCC 17029]
Length = 351
Score = 357 bits (918), Expect = 7e-97, Method: Composition-based stats.
Identities = 153/363 (42%), Positives = 206/363 (56%), Gaps = 14/363 (3%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE +P E R LTP LIA+G ++ VE S +I Y AG I P
Sbjct: 1 MTHLWVRAEQRPNEERVGLTPEGAAALIARGLRVTVEASRTRALSIEGYAAAGCAIAPEN 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW TAP D I+ GLKE+PE T PL H HI F H YK Q + +L RF G GTLYDLE
Sbjct: 61 SWPTAPADAIVFGLKELPEDGT-PLRHRHILFGHAYKGQPAGRILLERFRAGGGTLYDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
L ++ GRRVAAFG++AG+AGAA+ ++ WA + V+ +P + L+ D+ +
Sbjct: 120 SLVDESGRRVAAFGYWAGYAGAAVALKCWAAQAR---GGICDPVTTWPGREGLLADLGAE 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
A A R+P L+IGA GR G+GA DL +G+ + +WD++ET+ GGPF E+
Sbjct: 177 LTSAGA---RQPRALVIGARGRVGTGAADLCESMGLA---VTRWDMEETAHGGPFPEVLA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
+IF+NCI F E L P R LR + D++ D T+ +P+ +Y T + P
Sbjct: 231 HEIFLNCILARPGCPVFVPAEALEAP-RALRVIGDIACDPTSDFSPVKVYNRTTSWTAPA 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
+ V P L V++ID+LPSLLP E+S ++ LLPSL L R VW RAK FDR
Sbjct: 290 LRVHDD--PMLDVMAIDNLPSLLPVESSVDYAAQLLPSLLTL-DRIEEGVWGRAKAEFDR 346
Query: 363 HCA 365
H
Sbjct: 347 HMT 349
>ref|YP_681080.1| saccharopine dehydrogenase, putative [Roseobacter denitrificans OCh
114]
gb|ABG30394.1| saccharopine dehydrogenase, putative [Roseobacter denitrificans OCh
114]
Length = 350
Score = 357 bits (917), Expect = 7e-97, Method: Composition-based stats.
Identities = 144/365 (39%), Positives = 200/365 (54%), Gaps = 15/365 (4%)
Query: 3 AVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAG 62
L +RAE + E R LTP ++LIA G + VE SP Y G + PA
Sbjct: 1 MTHLWVRAEQRDNETRVGLTPDGARQLIASGITLTVEQSPTRVIPDAAYAATGCTMAPAH 60
Query: 63 SWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLE 122
SW AP+D II GLKE+PE T PL H HI F H +K Q + +L RF G GTL DLE
Sbjct: 61 SWPDAPKDAIIFGLKELPEDGT-PLPHRHIMFGHAFKGQPAGRVLLQRFKAGGGTLLDLE 119
Query: 123 FLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKD 182
+L +DQ RRVAAFG++AG+AGAA+ ++ WA +Q V+P+ + L+ D+ D
Sbjct: 120 YLVDDQNRRVAAFGYWAGYAGAAVALKCWAAQQR---GSIAGPVTPHDSSTHLLADLQSD 176
Query: 183 YKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQ 242
TG +PT LIIGALGR G+G DL +G+ KWD+ ET+ GGPF E+
Sbjct: 177 LLA---TGTHRPTALIIGALGRVGTGVFDLCTAMGVAC---TKWDMAETTGGGPFPEVLA 230
Query: 243 ADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPT 302
D+F NC+ F + + RRL + D++ D + +PI +Y T + +P
Sbjct: 231 HDLFFNCVLARPGTPVFVPAQTADAA-RRLSVIADIACDPDSDFSPIKVYDRTTTWAEPA 289
Query: 303 VLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDR 362
V P L V +ID+LPSLLP E+S+ ++ LLP+L L + + +W RA +
Sbjct: 290 RRVH--DQPMLDVTAIDNLPSLLPLESSQDYAAQLLPTLMSL--KDNSAIWQRAATTYRT 345
Query: 363 HCARV 367
H R+
Sbjct: 346 HRDRL 350
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.312 0.168 0.469
Lambda K H
0.267 0.0516 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,775,230,049
Number of Sequences: 6899187
Number of extensions: 397570469
Number of successful extensions: 1018765
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 2873
Number of HSP's successfully gapped in prelim test: 2152
Number of HSP's that attempted gapping in prelim test: 994857
Number of HSP's gapped (non-prelim): 11315
length of query: 373
length of database: 2,350,152,223
effective HSP length: 136
effective length of query: 237
effective length of database: 1,411,862,791
effective search space: 334611481467
effective search space used: 334611481467
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.1 bits)
S2: 80 (35.1 bits)