BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= YNL009W__[Saccharomyces_cerevisiae]
(420 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
6,899,187 sequences; 2,350,152,223 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
ref|NP_014389.1| Peroxisomal NADP-dependent isocitrate dehy... 825 0.0
gb|EDN62799.1| NADP-dependent isocitrate dehydrogenase [Sac... 823 0.0
gb|EDN59398.1| NADP-dependent isocitrate dehydrogenase [Sac... 651 0.0
ref|NP_013275.1| Cytosolic NADP-specific isocitrate dehydro... 651 0.0
ref|XP_445184.1| unnamed protein product [Candida glabrata]... 645 0.0
ref|NP_982520.1| AAL022Wp [Ashbya gossypii ATCC 10895] >gi|... 635 e-180
gb|AAA64516.1| isocitrate dehydrogenase 612 e-173
ref|XP_455638.1| unnamed protein product [Kluyveromyces lac... 612 e-173
ref|XP_001646497.1| hypothetical protein Kpol_1048p70 [Vand... 609 e-172
ref|XP_445447.1| unnamed protein product [Candida glabrata]... 592 e-167
ref|XP_451683.1| unnamed protein product [Kluyveromyces lac... 590 e-167
ref|XP_001646579.1| hypothetical protein Kpol_1055p78 [Vand... 583 e-165
ref|NP_984921.1| AER061Cp [Ashbya gossypii ATCC 10895] >gi|... 582 e-164
ref|XP_504978.1| hypothetical protein [Yarrowia lipolytica]... 582 e-164
ref|NP_010217.1| Mitochondrial NADP-specific isocitrate deh... 581 e-164
ref|XP_001527573.1| isocitrate dehydrogenase peroxisomal [L... 580 e-164
ref|XP_460289.1| hypothetical protein DEHA0E24134g [Debaryo... 579 e-163
ref|XP_001528456.1| isocitrate dehydrogenase, mitochondrial... 577 e-163
ref|XP_713421.1| cytosolic NADP-specific isocitrate dehydro... 577 e-163
ref|XP_001383685.1| Isocitrate dehydrogenase [NADP] peroxis... 575 e-162
ref|XP_446953.1| unnamed protein product [Candida glabrata]... 574 e-162
ref|XP_001485076.1| isocitrate dehydrogenase peroxisomal [P... 574 e-162
sp|O13294|IDH2_CANTR Isocitrate dehydrogenase [NADP] peroxi... 573 e-162
ref|XP_459772.1| hypothetical protein DEHA0E11286g [Debaryo... 570 e-161
ref|XP_001384028.1| Isocitrate dehydrogenase [NADP], mitoch... 570 e-161
ref|XP_001226620.1| conserved hypothetical protein [Chaetom... 568 e-160
ref|XP_710919.1| NADP-specific isocitrate dehydrogenase [Ca... 567 e-160
ref|XP_001903959.1| unnamed protein product [Podospora anse... 567 e-160
sp|O13285|IDH1_CANTR Isocitrate dehydrogenase [NADP], mitoc... 566 e-159
ref|XP_955850.1| hypothetical protein NCU03857 [Neurospora ... 565 e-159
ref|XP_001484278.1| isocitrate dehydrogenase, mitochondrial... 563 e-159
gb|AAK76730.1| mitochondrial NADP-dependent isocitrate dehy... 563 e-159
ref|XP_001593497.1| hypothetical protein SS1G_04924 [Sclero... 563 e-158
ref|YP_002761841.1| NADP-dependent isocitrate dehydrogenase... 561 e-158
ref|XP_367343.2| hypothetical protein MGG_07268 [Magnaporth... 561 e-158
ref|XP_390523.1| hypothetical protein FG10347.1 [Gibberella... 560 e-157
ref|XP_754749.1| isocitrate dehydrogenase Idp1 [Aspergillus... 559 e-157
gb|EDP52872.1| isocitrate dehydrogenase Idp1, putative [Asp... 559 e-157
gb|AAK76731.1| peroxisomal NADP-dependent isocitrate dehydr... 558 e-157
sp|P79089|IDHP_ASPNG Isocitrate dehydrogenase [NADP], mitoc... 553 e-156
gb|EDU40785.1| isocitrate dehydrogenase, mitochondrial prec... 553 e-155
ref|XP_001240510.1| isocitrate dehydrogenase NADP, mitochon... 551 e-155
ref|ZP_01862723.1| isocitrate dehydrogenase [Erythrobacter ... 550 e-155
ref|XP_660603.1| IDHP_ASPNG ISOCITRATE DEHYDROGENASE [NADP]... 549 e-154
ref|XP_001400371.1| precursor of mitochondrial isocitrate d... 547 e-154
ref|XP_001263574.1| isocitrate dehydrogenase Idp1, putative... 545 e-153
ref|YP_496560.1| isocitrate dehydrogenase [Novosphingobium ... 543 e-153
ref|ZP_01040029.1| isocitrate dehydrogenase [Erythrobacter ... 540 e-151
ref|YP_001413846.1| isocitrate dehydrogenase, NADP-dependen... 539 e-151
gb|EEJ98364.1| isocitrate dehydrogenase (NADP) [Thermomonos... 539 e-151
ref|ZP_03869030.1| isocitrate dehydrogenase (NADP) [Jonesia... 539 e-151
ref|YP_759895.1| isocitrate dehydrogenase [Hyphomonas neptu... 538 e-151
ref|NP_539708.1| isocitrate dehydrogenase [Brucella meliten... 537 e-151
ref|ZP_03922528.1| isocitrate dehydrogenase [Mobiluncus cur... 537 e-151
gb|AAC64182.1| NADP-dependent isocitrate dehydrogenase [Gly... 537 e-151
ref|XP_001818331.1| hypothetical protein [Aspergillus oryza... 537 e-151
ref|ZP_00952302.1| isocitrate dehydrogenase [Oceanicaulis a... 536 e-151
ref|XP_001778590.1| predicted protein [Physcomitrella paten... 536 e-151
ref|YP_001623415.1| isocitrate dehydrogenase (NADP) [Reniba... 536 e-150
sp|Q40345|IDHP_MEDSA Isocitrate dehydrogenase [NADP], chlor... 535 e-150
ref|NP_698203.1| isocitrate dehydrogenase [Brucella suis 13... 535 e-150
ref|NP_001043749.1| Os01g0654500 [Oryza sativa (japonica cu... 535 e-150
ref|ZP_03993927.1| isocitrate dehydrogenase [Mobiluncus mul... 533 e-150
ref|XP_001270886.1| isocitrate dehydrogenase Idp1, putative... 533 e-150
gb|AAA33978.1| NADPH-specific isocitrate dehydrogenase 533 e-150
ref|ZP_01303522.1| isocitrate dehydrogenase, NADP-dependent... 533 e-150
pir||S33612 isocitrate dehydrogenase (NADP) (EC 1.1.1.42) -... 533 e-150
ref|XP_001778805.1| predicted protein [Physcomitrella paten... 533 e-149
ref|YP_001370537.1| isocitrate dehydrogenase, NADP-dependen... 532 e-149
ref|YP_002826161.1| NADP isocitrate dehydrogenase [Rhizobiu... 532 e-149
ref|NP_421325.1| isocitrate dehydrogenase [Caulobacter cres... 531 e-149
ref|ZP_02166681.1| isocitrate dehydrogenase [Hoeflea photot... 531 e-149
ref|XP_536192.2| PREDICTED: similar to isocitrate dehydroge... 531 e-149
emb|CAD24779.1| isocitrate dehydrogenase [Cucumis sativus] 531 e-149
sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitoc... 531 e-149
sp|Q06197|IDHC_SOYBN Isocitrate dehydrogenase [NADP] (Oxalo... 531 e-149
ref|NP_786984.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 530 e-149
ref|YP_001524781.1| NADP-dependent isocitrate dehydrogenase... 530 e-148
gb|AAB39248.1| NADP-isocitrate dehydrogenase [Eucalyptus gl... 530 e-148
ref|NP_766599.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 530 e-148
ref|NP_196963.2| isocitrate dehydrogenase, putative / NADP+... 530 e-148
sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitoc... 529 e-148
dbj|BAC77065.1| NADP-specific isocitrate dehydrogenase [Lup... 529 e-148
gb|ACO14046.1| Isocitrate dehydrogenase, mitochondrial prec... 529 e-148
dbj|BAC77063.1| NADP-specific isocitrate dehydrogenase [Lup... 529 e-148
ref|YP_001685152.1| isocitrate dehydrogenase, NADP-dependen... 529 e-148
ref|NP_001026770.1| hypothetical protein LOC431056 [Gallus ... 529 e-148
ref|ZP_02124492.1| Isocitrate dehydrogenase (NADP(+)) [Meth... 528 e-148
ref|YP_673828.1| isocitrate dehydrogenase [Mesorhizobium sp... 528 e-148
ref|YP_756242.1| isocitrate dehydrogenase [Maricaulis maris... 528 e-148
ref|XP_762258.1| hypothetical protein UM06111.1 [Ustilago m... 528 e-148
ref|NP_001014183.1| isocitrate dehydrogenase 2 (NADP+), mit... 527 e-148
ref|ZP_02731825.1| isocitrate dehydrogenase [Gemmata obscur... 527 e-148
emb|CAA53300.1| isocitrate dehydrogenase (NADP+) [Solanum t... 527 e-148
ref|NP_001056381.1| Os05g0573200 [Oryza sativa (japonica cu... 527 e-148
emb|CAM77136.1| Isocitrate/isopropylmalate dehydrogenase [M... 527 e-148
sp|P50215|IDH_SPHYA Isocitrate dehydrogenase [NADP] (Oxalos... 527 e-148
emb|CAN72808.1| hypothetical protein [Vitis vinifera] >gi|1... 527 e-148
sp|P33198|IDHP_PIG Isocitrate dehydrogenase [NADP], mitocho... 527 e-148
ref|YP_001832264.1| isocitrate dehydrogenase, NADP-dependen... 527 e-148
ref|NP_002159.2| isocitrate dehydrogenase 2 (NADP+), mitoch... 527 e-148
ref|YP_001609735.1| NADP-dependent isocitrate dehydrogenase... 527 e-148
emb|CAA49208.1| isocitrate dehydrogenase (NADP+) [Homo sapi... 527 e-148
gb|AAS49171.1| NADP-dependent isocitrate dehydrogenase [Pis... 526 e-148
ref|XP_001369305.1| PREDICTED: hypothetical protein [Monode... 526 e-148
gb|AAL11503.1|AF367443_1 NADP-dependent isocitrate dehydrog... 526 e-147
dbj|BAA34113.1| NADP specific isocitrate dehydrogenase [Dau... 526 e-147
pdb|1LWD|A Chain A, Crystal Structure Of Nadp-Dependent Iso... 526 e-147
gb|ABE98244.1| mitochondrial isocitrate dehydrogenase 2-lik... 526 e-147
gb|ABK24873.1| unknown [Picea sitchensis] 526 e-147
ref|YP_117132.1| isocitrate dehydrogenase [Nocardia farcini... 526 e-147
emb|CAG13105.1| unnamed protein product [Tetraodon nigrovir... 526 e-147
ref|YP_290624.1| isocitrate dehydrogenase [Thermobifida fus... 526 e-147
dbj|BAD96636.1| isocitrate dehydrogenase 2 (NADP+), mitocho... 526 e-147
dbj|BAC77064.1| NADP-specific isocitrate dehydrogenase [Lup... 526 e-147
ref|XP_510589.2| PREDICTED: isocitrate dehydrogenase 2 (NAD... 526 e-147
ref|YP_001849499.1| isocitrate dehydrogenase [NADP] Icd1 [M... 525 e-147
ref|YP_062774.1| isocitrate dehydrogenase [Leifsonia xyli s... 525 e-147
ref|YP_617009.1| isocitrate dehydrogenase [Sphingopyxis ala... 525 e-147
ref|ZP_03891012.1| isocitrate dehydrogenase (NADP) [Geoderm... 525 e-147
emb|CAB87626.1| isocitrate dehydrogenase-like protein [Arab... 525 e-147
ref|XP_001095686.1| PREDICTED: isocitrate dehydrogenase 2 (... 525 e-147
ref|NP_970434.1| isocitrate dehydrogenase [Bdellovibrio bac... 525 e-147
ref|NP_962389.1| isocitrate dehydrogenase [Mycobacterium av... 525 e-147
ref|YP_883449.1| isocitrate dehydrogenase [Mycobacterium av... 525 e-147
sp|P50217|IDHC_SOLTU Isocitrate dehydrogenase [NADP] (Oxalo... 525 e-147
dbj|BAE48792.1| NADP-isocitrate dehydrogenase [Codonopsis l... 524 e-147
dbj|BAA34112.1| NADP specific isocitrate dehydrogenase [Dau... 524 e-147
emb|CAA73139.1| isocitrate dehydrogenase (NADP+) [Apium gra... 524 e-147
ref|YP_872148.1| isocitrate dehydrogenase [Acidothermus cel... 524 e-147
ref|NP_955858.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 524 e-147
gb|ABA18651.1| cytosolic NADP+-isocitrate dehydrogenase [Po... 524 e-147
ref|YP_001233708.1| isocitrate dehydrogenase [Acidiphilium ... 524 e-147
ref|ZP_02858718.1| isocitrate dehydrogenase, NADP-dependent... 524 e-147
ref|ZP_02188085.1| Isocitrate dehydrogenase [alpha proteoba... 523 e-147
gb|AAD51361.1|AF176669_1 NADP-isocitrate dehydrogenase [Cit... 523 e-147
gb|AAT06312.1| isocitrate dehydrogenase [Rhizobium legumino... 523 e-147
ref|YP_989041.1| isocitrate dehydrogenase [Bartonella bacil... 523 e-147
ref|NP_385898.1| isocitrate dehydrogenase [Sinorhizobium me... 523 e-147
gb|EAX02083.1| isocitrate dehydrogenase 2 (NADP+), mitochon... 523 e-147
ref|YP_001538953.1| isocitrate dehydrogenase, NADP-dependen... 523 e-147
ref|YP_768215.1| isocitrate dehydrogenase [Rhizobium legumi... 523 e-146
gb|EDT29808.1| isocitrate dehydrogenase, NADP-dependent [Ol... 523 e-146
emb|CAA65503.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 523 e-146
ref|YP_001327198.1| isocitrate dehydrogenase [Sinorhizobium... 523 e-146
ref|YP_458429.1| isocitrate dehydrogenase [Erythrobacter li... 523 e-146
ref|YP_001260963.1| isocitrate dehydrogenase [Sphingomonas ... 523 e-146
ref|YP_001833636.1| isocitrate dehydrogenase, NADP-dependen... 523 e-146
sp|P50218|IDHC_TOBAC Isocitrate dehydrogenase [NADP] (Oxalo... 523 e-146
ref|YP_001769504.1| isocitrate dehydrogenase, NADP-dependen... 522 e-146
ref|YP_001160602.1| isocitrate dehydrogenase [Salinispora t... 522 e-146
ref|YP_706173.1| isocitrate dehydrogenase [Rhodococcus sp. ... 522 e-146
ref|XP_001837820.1| hypothetical protein CC1G_11465 [Coprin... 522 e-146
ref|YP_419971.1| isocitrate dehydrogenase [Magnetospirillum... 522 e-146
emb|CAA65504.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 522 e-146
ref|NP_001004799.1| MGC69505 protein [Xenopus tropicalis] >... 521 e-146
ref|XP_001562802.1| isocitrate dehydrogenase [NADP], mitoch... 521 e-146
ref|ZP_01018081.1| isocitrate dehydrogenase [Parvularcula b... 521 e-146
gb|AAF73472.1|AF268076_1 NADP-dependent isocitrate dehydrog... 521 e-146
ref|YP_032403.1| isocitrate dehydrogenase [Bartonella quint... 521 e-146
ref|XP_001168316.1| PREDICTED: isocitrate dehydrogenase 2 (... 521 e-146
ref|NP_772387.1| isocitrate dehydrogenase [Bradyrhizobium j... 521 e-146
ref|YP_001204807.1| isocitrate dehydrogenase [Bradyrhizobiu... 520 e-146
ref|YP_002783489.1| isocitrate dehydrogenase [Rhodococcus o... 520 e-146
ref|YP_001758392.1| isocitrate dehydrogenase, NADP-dependen... 520 e-145
ref|ZP_01885694.1| isocitrate dehydrogenase [Pedobacter sp.... 520 e-145
emb|CAG02362.1| unnamed protein product [Tetraodon nigrovir... 520 e-145
ref|YP_001241304.1| isocitrate dehydrogenase [Bradyrhizobiu... 520 e-145
ref|NP_175836.1| ICDH; isocitrate dehydrogenase (NADP+) [Ar... 519 e-145
ref|YP_033790.1| isocitrate dehydrogenase [Bartonella hense... 519 e-145
ref|ZP_02295934.1| isocitrate dehydrogenase, NADP-dependent... 518 e-145
ref|ZP_00056387.1| COG0538: Isocitrate dehydrogenases [Magn... 518 e-145
ref|YP_001296741.1| isocitrate dehydrogenase [Flavobacteriu... 518 e-145
ref|XP_001878769.1| predicted protein [Laccaria bicolor S23... 518 e-145
ref|NP_354851.2| isocitrate dehydrogenase [Agrobacterium tu... 517 e-145
ref|YP_487337.1| isocitrate dehydrogenase [Rhodopseudomonas... 517 e-145
ref|YP_002765452.1| NADP-dependent isocitrate dehydrogenase... 517 e-145
emb|CAO64975.1| unnamed protein product [Vitis vinifera] 517 e-145
ref|YP_001419447.1| isocitrate dehydrogenase, NADP-dependen... 517 e-145
gb|EAY58582.1| isocitrate dehydrogenase [NADP] icd1 [Mycoba... 516 e-145
ref|NP_949171.1| isocitrate dehydrogenase [Rhodopseudomonas... 516 e-145
gb|AAR05796.1| NADP+-isocitrate dehydrogenase [Pinus pinaster] 516 e-144
ref|XP_001168291.1| PREDICTED: isocitrate dehydrogenase 2 (... 516 e-144
gb|AAC52473.1| isocitrate dehydrogenase 516 e-144
prf||2211361A isocitrate dehydrogenase 516 e-144
ref|NP_217856.1| isocitrate dehydrogenase [Mycobacterium tu... 516 e-144
ref|ZP_00206729.1| COG0538: Isocitrate dehydrogenases [Bifi... 516 e-144
ref|NP_001080321.1| hypothetical protein LOC380013 [Xenopus... 516 e-144
ref|XP_847200.1| isocitrate dehydrogenase [NADP], mitochond... 516 e-144
ref|NP_696658.1| isocitrate dehydrogenase [Bifidobacterium ... 515 e-144
ref|NP_509875.1| C34F6.8 [Caenorhabditis elegans] >gi|38747... 515 e-144
ref|ZP_03813993.1| isocitrate dehydrogenase (NADP) [Beutenb... 515 e-144
ref|NP_176768.1| isocitrate dehydrogenase, putative / NADP+... 515 e-144
emb|CAA63220.1| isocitrate dehydrogenase (NAD+) [Solanum tu... 514 e-144
ref|ZP_01228834.1| NADP dependent isocitrate dehydrogenase ... 514 e-144
ref|ZP_02918686.1| hypothetical protein BIFDEN_01996 [Bifid... 514 e-144
ref|ZP_01546031.1| isocitrate dehydrogenase [Stappia aggreg... 514 e-144
ref|YP_979491.1| isocitrate dehydrogenase [Mycobacterium bo... 514 e-144
ref|XP_001020930.2| dehydrogenase, isocitrate/isopropylmala... 514 e-144
gb|AAV33246.1| isocitrate dehydrogenase [Toxoplasma gondii] 514 e-144
ref|YP_568874.1| isocitrate dehydrogenase [Rhodopseudomonas... 514 e-144
ref|NP_001042583.1| Os01g0248400 [Oryza sativa (japonica cu... 514 e-144
ref|YP_001363715.1| isocitrate dehydrogenase, NADP-dependen... 514 e-144
ref|YP_425448.1| isocitrate dehydrogenase [Rhodospirillum r... 514 e-144
gb|ABF20244.1| mitochondrial isocitrate dehydrogenase [Leis... 514 e-144
ref|XP_001681361.1| isocitrate dehydrogenase [NADP], mitoch... 514 e-144
ref|ZP_03977360.1| isocitrate dehydrogenase (NADP(+)) [Bifi... 513 e-144
gb|AAM13090.1| similar to NADP-specific isocitrate dehydrog... 513 e-144
gb|ABF20272.1| mitochondrial isocitrate dehydrogenase [Leis... 513 e-144
gb|AAM65674.1| isocitrate dehydrogenase, putative [Arabidop... 513 e-144
ref|XP_001463680.1| isocitrate dehydrogenase [NADP], mitoch... 513 e-143
ref|XP_821599.1| isocitrate dehydrogenase, putative [Trypan... 513 e-143
ref|ZP_02955422.1| isocitrate dehydrogenase, NADP-dependent... 513 e-143
ref|XP_569234.1| isocitrate dehydrogenase (NADP+) [Cryptoco... 513 e-143
ref|XP_569233.1| isocitrate dehydrogenase (NADP+) [Cryptoco... 513 e-143
emb|CAD24782.1| isocitrate dehydrogenase [Arabidopsis thali... 513 e-143
ref|YP_909639.1| isocitrate dehydrogenase [Bifidobacterium ... 513 e-143
ref|YP_001709366.1| isocitrate dehydrogenase [Clavibacter m... 512 e-143
ref|XP_001698704.1| isocitrate dehydrogenase, NADP-dependen... 512 e-143
ref|ZP_01130474.1| isocitrate dehydrogenase [marine actinob... 512 e-143
ref|XP_813368.1| isocitrate dehydrogenase [NADP], mitochond... 512 e-143
ref|ZP_03896321.1| isocitrate dehydrogenase (NADP) [Dyadoba... 512 e-143
ref|XP_001168261.1| PREDICTED: isocitrate dehydrogenase 2 (... 512 e-143
ref|NP_101923.1| isocitrate dehydrogenase [Mesorhizobium lo... 511 e-143
gb|EAY99113.1| hypothetical protein OsI_020346 [Oryza sativ... 511 e-143
ref|ZP_03819206.1| isocitrate dehydrogenase (NADP) [Actinos... 511 e-143
ref|YP_001108727.1| isocitrate dehydrogenase [Saccharopolys... 511 e-143
ref|YP_317907.1| isocitrate dehydrogenase [Nitrobacter wino... 510 e-143
ref|YP_001223282.1| isocitrate dehydrogenase [Clavibacter m... 510 e-143
ref|XP_001688948.1| AGAP006660-PA [Anopheles gambiae str. P... 510 e-143
ref|ZP_02302766.1| isocitrate dehydrogenase, NADP-dependent... 510 e-143
ref|YP_531457.1| isocitrate dehydrogenase [Rhodopseudomonas... 510 e-143
ref|ZP_01440188.1| Isocitrate/isopropylmalate dehydrogenase... 510 e-142
ref|YP_001043974.1| isocitrate dehydrogenase [Rhodobacter s... 509 e-142
ref|YP_351602.1| isocitrate dehydrogenase [Rhodobacter spha... 509 e-142
ref|XP_312860.4| AGAP003168-PA [Anopheles gambiae str. PEST... 509 e-142
ref|XP_001426548.1| hypothetical protein GSPATT00029781001 ... 509 e-142
ref|YP_682929.1| isocitrate dehydrogenase [Roseobacter deni... 508 e-142
gb|ABF20271.1| mitochondrial isocitrate dehydrogenase [Leis... 508 e-142
ref|YP_001169228.1| isocitrate dehydrogenase [Rhodobacter s... 508 e-142
ref|NP_001053269.1| Os04g0508200 [Oryza sativa (japonica cu... 508 e-142
ref|YP_001042101.1| isocitrate dehydrogenase [Rhodobacter s... 508 e-142
ref|YP_353519.1| isocitrate dehydrogenase [Rhodobacter spha... 508 e-142
ref|XP_001676039.1| Hypothetical protein CBG17397 [Caenorha... 508 e-142
ref|YP_780531.1| isocitrate dehydrogenase [Rhodopseudomonas... 507 e-142
ref|YP_677841.1| isocitrate dehydrogenase [Cytophaga hutchi... 507 e-142
ref|ZP_01046178.1| isocitrate dehydrogenase NADP-dependent ... 507 e-142
ref|XP_001457045.1| hypothetical protein GSPATT00022820001 ... 507 e-142
ref|YP_001601185.1| Isocitrate dehydrogenase [Gluconacetoba... 507 e-142
ref|YP_001168561.1| isocitrate dehydrogenase [Rhodobacter s... 507 e-142
ref|ZP_02981592.1| isocitrate dehydrogenase, NADP-dependent... 506 e-141
emb|CAE04728.1| OSJNBa0043L24.16 [Oryza sativa (japonica cu... 506 e-141
ref|NP_113698.1| isocitrate dehydrogenase 1 (NADP+), solubl... 506 e-141
ref|YP_576902.1| isocitrate dehydrogenase [Nitrobacter hamb... 505 e-141
gb|ABU41004.1| isocitrate dehydrogenase 1 [Anser anser] 505 e-141
ref|NP_001009276.1| cytosolic NADP-isocitrate dehydrogenase... 505 e-141
emb|CAH67563.1| OSIGBa0101P20.6 [Oryza sativa (indica culti... 505 e-141
ref|XP_001650675.1| nadp-specific isocitrate dehydrogenase ... 505 e-141
ref|ZP_01157336.1| isocitrate dehydrogenase [Oceanicola gra... 504 e-141
gb|ABL97438.1| isocitrate dehydrogenase [uncultured marine ... 504 e-141
sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytopl... 504 e-141
ref|ZP_00964081.1| isocitrate dehydrogenase [Sulfitobacter ... 504 e-141
ref|XP_001017274.1| isocitrate dehydrogenase, NADP-dependen... 504 e-141
ref|XP_421965.2| PREDICTED: similar to cytosolic NADP-depen... 504 e-141
ref|ZP_00954676.1| isocitrate dehydrogenase [Sulfitobacter ... 504 e-141
ref|XP_001176537.1| PREDICTED: similar to Isocitrate dehydr... 504 e-141
ref|XP_970446.1| PREDICTED: similar to isocitrate dehydroge... 504 e-141
sp|Q5R9C5|IDHC_PONPY Isocitrate dehydrogenase [NADP] cytopl... 503 e-141
sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytopl... 503 e-141
ref|XP_001107627.1| PREDICTED: isocitrate dehydrogenase 1 (... 503 e-141
ref|XP_001208968.1| isocitrate dehydrogenase, mitochondrial... 503 e-140
ref|NP_926944.1| isocitrate dehydrogenase [Gloeobacter viol... 503 e-140
ref|XP_001141655.1| PREDICTED: isocitrate dehydrogenase 1 (... 503 e-140
ref|XP_001511049.1| PREDICTED: similar to cytosolic NADP-de... 503 e-140
ref|NP_001088022.1| hypothetical protein LOC494713 [Xenopus... 503 e-140
gb|ABK25438.1| unknown [Picea sitchensis] 503 e-140
emb|CAG38738.1| IDH1 [Homo sapiens] 502 e-140
ref|NP_005887.2| isocitrate dehydrogenase 1 (NADP+), solubl... 502 e-140
ref|YP_266067.1| isocitrate dehydrogenase [Candidatus Pelag... 502 e-140
ref|ZP_00960755.1| Isocitrate dehydrogenase [Roseovarius nu... 502 e-140
dbj|BAC39792.1| unnamed protein product [Mus musculus] 501 e-140
ref|XP_828183.1| isocitrate dehydrogenase [Trypanosoma bruc... 501 e-140
emb|CAB66637.1| hypothetical protein [Homo sapiens] >gi|117... 501 e-140
ref|YP_001926024.1| isocitrate dehydrogenase, NADP-dependen... 501 e-140
emb|CAH89719.1| hypothetical protein [Pongo abelii] 501 e-140
gb|AAD02918.1| NADP-dependent isocitrate dehydrogenase [Hom... 501 e-140
ref|NP_851355.2| isocitrate dehydrogenase 1 (NADP+), solubl... 501 e-140
ref|NP_034627.3| isocitrate dehydrogenase 1 (NADP+), solubl... 501 e-140
gb|AAH88986.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 501 e-140
gb|AAH93020.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 500 e-140
dbj|BAE39644.1| unnamed protein product [Mus musculus] 500 e-140
ref|XP_850187.1| PREDICTED: similar to Isocitrate dehydroge... 500 e-140
emb|CAH91635.1| hypothetical protein [Pongo abelii] 499 e-139
sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytopl... 499 e-139
pdb|2CMJ|A Chain A, Crystal Structure Of Mouse Cytosolic Is... 499 e-139
ref|XP_001845030.1| isocitrate dehydrogenase [Culex pipiens... 499 e-139
gb|ABO93633.1| isocitrate dehydrogenase 2 [Toxoplasma gondii] 499 e-139
ref|YP_745187.1| isocitrate dehydrogenase [Granulibacter be... 499 e-139
emb|CAG38553.1| IDH1 [Homo sapiens] 499 e-139
ref|XP_001670101.1| Hypothetical protein CBG21657 [Caenorha... 499 e-139
>ref|NP_014389.1| Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes
oxidation of isocitrate to alpha-ketoglutarate with the
formation of NADP(H+), required for growth on
unsaturated fatty acids; Idp3p [Saccharomyces
cerevisiae]
sp|P53982|IDHH_YEAST Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase)
(IDH) (NADP(+)-specific ICDH) (IDP)
emb|CAA95869.1| unnamed protein product [Saccharomyces cerevisiae]
gb|AAT93173.1| YNL009W [Saccharomyces cerevisiae]
Length = 420
Score = 825 bits (2130), Expect = 0.0, Method: Composition-based stats.
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS
Sbjct: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL
Sbjct: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM
Sbjct: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ
Sbjct: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG
Sbjct: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE
Sbjct: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL 420
KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL
Sbjct: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL 420
>gb|EDN62799.1| NADP-dependent isocitrate dehydrogenase [Saccharomyces cerevisiae
YJM789]
Length = 420
Score = 823 bits (2127), Expect = 0.0, Method: Composition-based stats.
Identities = 419/420 (99%), Positives = 419/420 (99%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS
Sbjct: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL
Sbjct: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDG ENIDLKVYEFPKSGGIAM
Sbjct: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGTENIDLKVYEFPKSGGIAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ
Sbjct: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG
Sbjct: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE
Sbjct: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL 420
KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL
Sbjct: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL 420
>gb|EDN59398.1| NADP-dependent isocitrate dehydrogenase [Saccharomyces cerevisiae
YJM789]
Length = 412
Score = 651 bits (1680), Expect = 0.0, Method: Composition-based stats.
Identities = 312/404 (77%), Positives = 366/404 (90%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +PIVEMDGDEQTR+IW LI++KL+LPYLDVDLKYYDLS++ RD+TNDQVT DS
Sbjct: 1 MTKIKVANPIVEMDGDEQTRIIWHLIRDKLVLPYLDVDLKYYDLSVEYRDQTNDQVTVDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ ATLKYGVAVKCATITPDEAR++EF+LK+MWKSPNGTIRNILGGTVFREPIIIP+IPRL
Sbjct: 61 ATATLKYGVAVKCATITPDEARVEEFHLKKMWKSPNGTIRNILGGTVFREPIIIPRIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP WEKPIIIGRHAFGDQY+ATD+ + + G+LRL + S G ++DLKV+++P+ GG+AM
Sbjct: 121 VPQWEKPIIIGRHAFGDQYKATDVIVPEEGELRLVYKSKSGTHDVDLKVFDYPEHGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+NT DSI+GFAKASFELA++RKLPL+ TTKNTILK YD +FK +F+ ++ K YKEKF+
Sbjct: 181 MMYNTTDSIEGFAKASFELAIERKLPLYSTTKNTILKKYDGKFKDVFEAMYAKSYKEKFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
+L I YEHRLIDDMVAQMLKSKGG+IIAMKNYDGDV+SDIVAQGFGSLGLMTS+LITPDG
Sbjct: 241 SLGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFESEAAHGTVTRHFR+HQ+G+ETSTNSIASIFAWTR IIQRGKLDNT DV+KFG +LE
Sbjct: 301 KTFESEAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
AT++TVQ G MTKDLAL+LGK+ RS+YVTTEEFID V RL+
Sbjct: 361 SATVNTVQEDGIMTKDLALILGKSERSAYVTTEEFIDAVESRLK 404
>ref|NP_013275.1| Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes
oxidation of isocitrate to alpha-ketoglutarate; levels
are elevated during growth on non-fermentable carbon
sources and reduced during growth on glucose; Idp2p
[Saccharomyces cerevisiae]
sp|P41939|IDHC_YEAST Isocitrate dehydrogenase [NADP] cytoplasmic (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAB67464.1| Idp2p: isocitrate dehydrogenase [Saccharomyces cerevisiae]
Length = 412
Score = 651 bits (1679), Expect = 0.0, Method: Composition-based stats.
Identities = 311/404 (76%), Positives = 366/404 (90%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +PIVEMDGDEQTR+IW LI++KL+LPYLDVDLKYYDLS++ RD+TNDQVT DS
Sbjct: 1 MTKIKVANPIVEMDGDEQTRIIWHLIRDKLVLPYLDVDLKYYDLSVEYRDQTNDQVTVDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ ATLKYGVAVKCATITPDEAR++EF+LK+MWKSPNGTIRNILGGTVFREPIIIP+IPRL
Sbjct: 61 ATATLKYGVAVKCATITPDEARVEEFHLKKMWKSPNGTIRNILGGTVFREPIIIPRIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP WEKPIIIGRHAFGDQY+ATD+ + + G+LRL + S G ++DLKV+++P+ GG+AM
Sbjct: 121 VPQWEKPIIIGRHAFGDQYKATDVIVPEEGELRLVYKSKSGTHDVDLKVFDYPEHGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+NT DSI+GFAKASFELA++RKLPL+ TTKNTILK YD +FK +F+ ++ + YKEKF+
Sbjct: 181 MMYNTTDSIEGFAKASFELAIERKLPLYSTTKNTILKKYDGKFKDVFEAMYARSYKEKFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
+L I YEHRLIDDMVAQMLKSKGG+IIAMKNYDGDV+SDIVAQGFGSLGLMTS+LITPDG
Sbjct: 241 SLGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFESEAAHGTVTRHFR+HQ+G+ETSTNSIASIFAWTR IIQRGKLDNT DV+KFG +LE
Sbjct: 301 KTFESEAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
AT++TVQ G MTKDLAL+LGK+ RS+YVTTEEFID V RL+
Sbjct: 361 SATVNTVQEDGIMTKDLALILGKSERSAYVTTEEFIDAVESRLK 404
>ref|XP_445184.1| unnamed protein product [Candida glabrata]
emb|CAG58084.1| unnamed protein product [Candida glabrata CBS 138]
Length = 411
Score = 645 bits (1664), Expect = 0.0, Method: Composition-based stats.
Identities = 310/405 (76%), Positives = 366/405 (90%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK+KVV+PIVEMDGDEQTR+IW LI+EKLILP+LDVDLKYYDLSI+ RD TND+VT+DS
Sbjct: 1 MSKVKVVNPIVEMDGDEQTRIIWHLIREKLILPFLDVDLKYYDLSIEYRDETNDKVTEDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ ATLKYGVAVKCATITPDEAR++EFNLKEMWKSPNGTIRNILGGTVFREPI+IP+IP+L
Sbjct: 61 ALATLKYGVAVKCATITPDEARVEEFNLKEMWKSPNGTIRNILGGTVFREPIVIPRIPKL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W++PIIIGRHAFGDQYRATD+ I G++RL + S DGK +ID+ VY FPK GG+AM
Sbjct: 121 VPQWKEPIIIGRHAFGDQYRATDVVIPDEGEVRLVYKSKDGKTDIDIPVYNFPKEGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+NT +SI+GFA+ASF +AL+ ++PL+ TTKNTILK YD +FK F+++++ EYKE+F+
Sbjct: 181 MMYNTTESIRGFARASFNMALEHEMPLYSTTKNTILKKYDGKFKDTFESMYEAEYKEQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQMLKSKGGFIIAMKNYDGDV+SDIVAQGFGSLGLMTS+LI+PDG
Sbjct: 241 AKGIWYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVESDIVAQGFGSLGLMTSVLISPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFESEAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR IIQRGKLD T DV+KFG LLE
Sbjct: 301 KTFESEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGIIQRGKLDETADVVKFGELLE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQN 405
+AT+DTVQ G MTKDLAL+LGKT+RS+YVTTEEFID V R+++
Sbjct: 361 RATVDTVQEDGIMTKDLALILGKTDRSAYVTTEEFIDAVENRIKS 405
>ref|NP_982520.1| AAL022Wp [Ashbya gossypii ATCC 10895]
gb|AAS50344.1| AAL022Wp [Ashbya gossypii ATCC 10895]
Length = 415
Score = 635 bits (1638), Expect = e-180, Method: Composition-based stats.
Identities = 310/407 (76%), Positives = 356/407 (87%), Gaps = 2/407 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M K+KV PIVEMDGDEQTR+IW LIK++LI PYLDVDLKYYDLSI+ RD T D+VT +S
Sbjct: 1 MGKVKVQQPIVEMDGDEQTRIIWHLIKDQLIFPYLDVDLKYYDLSIENRDATEDRVTVES 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ ATLKYGVAVKCATITPDEAR++EF LKEMWKSPNGTIRNILGGTVFREPIIIP+IPRL
Sbjct: 61 AEATLKYGVAVKCATITPDEARVEEFGLKEMWKSPNGTIRNILGGTVFREPIIIPRIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDG--KENIDLKVYEFPKSGGI 178
VP W +PII+GRHAFGDQY+ATD+ I G L+L F S DG +N+DL+V+E+PK GG+
Sbjct: 121 VPGWNEPIIVGRHAFGDQYKATDVVIPGEGTLKLVFESKDGDKSKNLDLEVFEYPKDGGV 180
Query: 179 AMAMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEK 238
AM M+NT DSI GFAK+SFELAL+RK+PL+ TTKNTILK YD +FK IF+ ++ EYKEK
Sbjct: 181 AMTMYNTTDSITGFAKSSFELALQRKMPLYSTTKNTILKKYDGKFKDIFEGMYAAEYKEK 240
Query: 239 FQALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITP 298
F+A I YEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTS+L++P
Sbjct: 241 FEAAGIWYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVSP 300
Query: 299 DGKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNL 358
DGKTFESEAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR II RGK+D T DV+KFG L
Sbjct: 301 DGKTFESEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGIIHRGKVDGTPDVVKFGEL 360
Query: 359 LEKATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQN 405
LEK+TLDTVQ MTKDLAL+LGKT+R+SYVTTEEFI VA RL +
Sbjct: 361 LEKSTLDTVQEDNIMTKDLALILGKTDRASYVTTEEFITAVANRLAD 407
>gb|AAA64516.1| isocitrate dehydrogenase
Length = 411
Score = 612 bits (1579), Expect = e-173, Method: Composition-based stats.
Identities = 296/404 (73%), Positives = 352/404 (87%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +PIVEMDGDEQTR+IW ++KL+LPYLDVDLKYYDLS++ RD+TNDQVT DS
Sbjct: 1 MTKIKVANPIVEMDGDEQTRIIWSFNQDKLVLPYLDVDLKYYDLSVEYRDQTNDQVTVDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ ATLKY VAVKCATITPDEAR++EF+LK+MWKSPNGTIRNILGGTVFREPIIIP+IPRL
Sbjct: 61 ATATLKYRVAVKCATITPDEARVEEFHLKKMWKSPNGTIRNILGGTVFREPIIIPRIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP WEKPIIIGRHAFGDQY+ATD+ + + G+LRL + S G ++DLKV+++P+ GG+AM
Sbjct: 121 VPQWEKPIIIGRHAFGDQYKATDVIVPEEGELRLVYKSKSGTHDVDLKVFDYPEHGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N DSI+GFAKASFELA++RKLPL+ TTKNTILK YD +FK +F+ ++ + K +
Sbjct: 181 MMYNNTDSIEGFAKASFELAIERKLPLYSTTKNTILKKYDGKFKDVFEAMYLEVIKRSLE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
+L I YEHRLIDDMVAQMLKSKGG+I+AMKNYDGDV+SDIVAQGFGSLGLMTS+LITPDG
Sbjct: 241 SLGIWYEHRLIDDMVAQMLKSKGGYIMAMKNYDGDVESDIVAQGFGSLGLMTSVLITPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFES+ AHGTVTRH + +G ETSTNSIASIFAWTR IIQRGKLDNT DV+KFG +LE
Sbjct: 301 KTFESDRAHGTVTRHLTDYDKGRETSTNSIASIFAWTRGIIQRGKLDNTPDVVKFGQILE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
AT++TVQ G MTKDLAL+LGK+ RS+YVTTEEFID V RL+
Sbjct: 361 SATVNTVQEDGIMTKDLALILGKSERSAYVTTEEFIDAVESRLK 404
>ref|XP_455638.1| unnamed protein product [Kluyveromyces lactis]
emb|CAG98346.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
Length = 415
Score = 612 bits (1578), Expect = e-173, Method: Composition-based stats.
Identities = 307/413 (74%), Positives = 359/413 (86%), Gaps = 3/413 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSKI V PIVEMDGDEQTR+IWKLIK+ LI PYLD+DLKYYDLSI+ RD T+D+VT+ S
Sbjct: 1 MSKISVKTPIVEMDGDEQTRIIWKLIKDHLIHPYLDIDLKYYDLSIENRDLTDDKVTEQS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ ATLKYGVAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPI+IP+IP+L
Sbjct: 61 AQATLKYGVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIVIPRIPKL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGK-ENIDLKVYEFPKS--GG 177
V +WEKPIIIGRHAFGDQYRATD+ I AGKL+L F SDD ENI+L VY+F + GG
Sbjct: 121 VTNWEKPIIIGRHAFGDQYRATDVVIPGAGKLKLVFESDDSNTENIELSVYDFDEESKGG 180
Query: 178 IAMAMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKE 237
+AMAM+NT +SI GFA ASF++AL+R LPL+ TTKNTILK YD +FK +F++L++ +YK
Sbjct: 181 VAMAMYNTLESITGFAHASFKMALERGLPLYSTTKNTILKKYDGKFKDVFESLYESQYKS 240
Query: 238 KFQALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILIT 297
F+A I YEHRLIDDMVAQMLKSKGG+IIAMKNYDGDV+SDIVAQGFGSLGLMTS+LIT
Sbjct: 241 AFEAKGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVESDIVAQGFGSLGLMTSVLIT 300
Query: 298 PDGKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGN 357
PDGK FESEAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR +IQRGKLD+T DV+KF
Sbjct: 301 PDGKAFESEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGLIQRGKLDSTPDVVKFAE 360
Query: 358 LLEKATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSS 410
L+E AT++TVQ MTKDLAL+LGKT+RSSYVTTEEFI+ V KRL + SS
Sbjct: 361 LVESATVNTVQEDEIMTKDLALILGKTDRSSYVTTEEFIEAVHKRLDSEFKSS 413
>ref|XP_001646497.1| hypothetical protein Kpol_1048p70 [Vanderwaltozyma polyspora DSM
70294]
gb|EDO18639.1| hypothetical protein Kpol_1048p70 [Vanderwaltozyma polyspora DSM
70294]
Length = 419
Score = 609 bits (1570), Expect = e-172, Method: Composition-based stats.
Identities = 301/408 (73%), Positives = 362/408 (88%), Gaps = 5/408 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS IKV +PIVEMDGDEQTR+IW+LIK+KLILP+LDV+LKYYDL I+ RD+TND+V+K+S
Sbjct: 1 MSLIKVKNPIVEMDGDEQTRIIWRLIKDKLILPFLDVNLKYYDLGIEYRDKTNDKVSKES 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ ATLKYGVAVKCATITPDEAR++EF LK+MW+SPNGTIRN++GGTVFREPIIIPKIPRL
Sbjct: 61 AEATLKYGVAVKCATITPDEARVQEFKLKKMWESPNGTIRNVIGGTVFREPIIIPKIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKK---AGKLRLQFSSDDGKENIDLKVYEFPKS-- 175
VP WEKPIIIGRHA+GDQY+A D+ I + G ++L ++SDDGK NI+L V++F +
Sbjct: 121 VPGWEKPIIIGRHAYGDQYKAADMVIPEDNNKGIVKLVYTSDDGKTNIELPVHQFDGNDD 180
Query: 176 GGIAMAMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEY 235
GGIA+ MFNT SIKGFA +SFE AL++ LPL+ TTKNTILK YD Q+K IF+++++K+Y
Sbjct: 181 GGIALGMFNTTRSIKGFAHSSFEFALEKGLPLYSTTKNTILKKYDGQYKDIFNDMYEKDY 240
Query: 236 KEKFQALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSIL 295
K+KF+A I YEHRLIDDMVAQMLKSKGGF+IAMKNYDGDVQSD+VAQGFGSLGLM+SIL
Sbjct: 241 KDKFEAKGIWYEHRLIDDMVAQMLKSKGGFVIAMKNYDGDVQSDVVAQGFGSLGLMSSIL 300
Query: 296 ITPDGKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKF 355
I+ DGKTFESEAAHGTVTRH+R+HQ+G+ETSTNSIASIFAW++ IIQRGK+D T DV++F
Sbjct: 301 ISDDGKTFESEAAHGTVTRHYRQHQQGKETSTNSIASIFAWSKGIIQRGKIDGTADVVQF 360
Query: 356 GNLLEKATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRL 403
G LLE AT+DTVQ+ MTKDLAL+LGKT RSSYVTTEEFI+ VAKRL
Sbjct: 361 GELLESATIDTVQIDDVMTKDLALILGKTERSSYVTTEEFIEAVAKRL 408
>ref|XP_445447.1| unnamed protein product [Candida glabrata]
emb|CAG58358.1| unnamed protein product [Candida glabrata CBS 138]
Length = 423
Score = 592 bits (1527), Expect = e-167, Method: Composition-based stats.
Identities = 293/410 (71%), Positives = 348/410 (84%), Gaps = 2/410 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
++KIKV P+VE+DGDE TR+IW IK++LILP+LDVDLKYYDLSIQ RD+T DQ+T DS
Sbjct: 13 LAKIKVKTPVVELDGDEMTRIIWDKIKKQLILPFLDVDLKYYDLSIQSRDKTKDQITHDS 72
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR+KEFNL +MWKSPNGTIRNILGGTVFREPI+IP++PRL
Sbjct: 73 AEAIKKYGVGVKCATITPDEARVKEFNLTKMWKSPNGTIRNILGGTVFREPIVIPRVPRL 132
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSD-DGKENIDLKVYEFPKSGGIA 179
VP WEKPIIIGRHA GDQY+ATD I GKL L + + D + ++VY++ K G+A
Sbjct: 133 VPGWEKPIIIGRHAHGDQYKATDAVIPGQGKLELVYKPNGDASKAEVMEVYDY-KGPGVA 191
Query: 180 MAMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKF 239
+AM+NT++SI+GFA +SF+LAL++KL LF +TKNTILK YD +FK IF ++D EYK+KF
Sbjct: 192 LAMYNTDESIRGFAHSSFKLALQKKLNLFLSTKNTILKKYDGRFKDIFQEVYDSEYKQKF 251
Query: 240 QALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPD 299
L ITYEHRLIDDMVAQM+KSKGGFI+A+KNYDGDVQSDIVAQGFGSLGLMTSILITPD
Sbjct: 252 AELNITYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILITPD 311
Query: 300 GKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLL 359
GKTFESEAAHGTVTRH+RKHQ+GEETSTNSIASIFAWTR + +RG+LD T DV++F N+L
Sbjct: 312 GKTFESEAAHGTVTRHYRKHQQGEETSTNSIASIFAWTRGLAKRGELDGTPDVVRFANIL 371
Query: 360 EKATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
E ATL+TVQ G MTKDLAL GKT+R+SYVTT EF+D V KRLQ + S
Sbjct: 372 ESATLNTVQQDGIMTKDLALACGKTDRASYVTTTEFLDAVEKRLQTEIKS 421
>ref|XP_451683.1| unnamed protein product [Kluyveromyces lactis]
emb|CAH02076.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
Length = 429
Score = 590 bits (1522), Expect = e-167, Method: Composition-based stats.
Identities = 287/405 (70%), Positives = 341/405 (84%), Gaps = 1/405 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KIKV P+VE+DGDE TR+IW IK KLILPYLDVDLKYYDLS+ RD TNDQVT DS
Sbjct: 20 LRKIKVQTPVVELDGDEMTRIIWDKIKSKLILPYLDVDLKYYDLSVTNRDATNDQVTVDS 79
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDE R+KEFNLK+MWKSPNGTIRNILGGTVFREPI+IP+IPRL
Sbjct: 80 ANAIKKYGVGVKCATITPDEGRVKEFNLKKMWKSPNGTIRNILGGTVFREPIVIPRIPRL 139
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP WEKPI+IGRHA GDQY+ATD+ + GKL L + DG E L+VY++ K GIA+
Sbjct: 140 VPGWEKPIVIGRHAHGDQYKATDLVVPGPGKLELVYKPTDGSETKTLEVYDY-KGPGIAL 198
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+NT++SI+GFA ASF+LA+ +KL L+ +TKNTILK YD +FK IF ++D EYK +F+
Sbjct: 199 AMYNTDESIRGFAHASFKLAITKKLNLYLSTKNTILKKYDGRFKDIFQEIYDSEYKSEFE 258
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
L I YEHRLIDDMVAQM+KSKGGFI+A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 259 KLGIWYEHRLIDDMVAQMIKSKGGFILAFKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDG 318
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
K FESEAAHGTVTRH+R++Q+G+ETSTNSIASIFAWTR + +RG+LDNT +V++F NLLE
Sbjct: 319 KAFESEAAHGTVTRHYRQYQQGKETSTNSIASIFAWTRGLAKRGELDNTPEVVEFANLLE 378
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQN 405
K+TL+TVQ G MTKDLAL G T+RSSYV T+EF+D V KR +N
Sbjct: 379 KSTLNTVQEDGIMTKDLALACGNTDRSSYVNTDEFLDAVEKRFRN 423
>ref|XP_001646579.1| hypothetical protein Kpol_1055p78 [Vanderwaltozyma polyspora DSM
70294]
gb|EDO18721.1| hypothetical protein Kpol_1055p78 [Vanderwaltozyma polyspora DSM
70294]
Length = 427
Score = 583 bits (1504), Expect = e-165, Method: Composition-based stats.
Identities = 287/416 (68%), Positives = 348/416 (83%), Gaps = 2/416 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+SKI V P+VE+DGDE TR+IW IK+ LILP+LDVDLKYYDLSI+ RD TNDQVT D+
Sbjct: 12 LSKITVKSPLVELDGDEMTRIIWSKIKKNLILPFLDVDLKYYDLSIENRDSTNDQVTVDA 71
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +GV VKCATITPDEAR++EFNLK+MWKSPNGTIRNILGGTVFREPI+IP+IPRL
Sbjct: 72 ANAIKNFGVGVKCATITPDEARVEEFNLKKMWKSPNGTIRNILGGTVFREPIVIPRIPRL 131
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFS-SDDGKENIDLKVYEFPKSGGIA 179
+P WEKPIIIGRHA GDQY+ATD I AGKL L F+ +D E L VY++ K+ G+A
Sbjct: 132 IPGWEKPIIIGRHAHGDQYKATDTLIPTAGKLELVFTPTDPNGERQILNVYDY-KNSGVA 190
Query: 180 MAMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKF 239
+AM+NT++SI+GFA +SF+LA+ +KL LF +TKNTILK YD +FK IF +++ +YK +F
Sbjct: 191 LAMYNTDESIRGFAHSSFKLAINKKLNLFLSTKNTILKKYDGRFKDIFQEIYESDYKSQF 250
Query: 240 QALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPD 299
+ L I+YEHRLIDDMVAQM+KSKGGFI+A+KNYDGDVQSDIVAQGFGSLGLMTS+L+TPD
Sbjct: 251 ENLGISYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSVLVTPD 310
Query: 300 GKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLL 359
GKTFESEAAHGTVTRH+R++++G+ETSTNSIASIFAW+R + +RG+LD+T DVIKF NLL
Sbjct: 311 GKTFESEAAHGTVTRHYRQYEQGKETSTNSIASIFAWSRGLAKRGELDSTPDVIKFANLL 370
Query: 360 EKATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKK 415
E ATL+TVQ G MTKDLAL GKT RS+YVTT+EF+D VA RL N S K
Sbjct: 371 ESATLNTVQQDGIMTKDLALACGKTERSAYVTTDEFLDAVATRLNNEFKSFENSSK 426
>ref|NP_984921.1| AER061Cp [Ashbya gossypii ATCC 10895]
gb|AAS52745.1| AER061Cp [Ashbya gossypii ATCC 10895]
Length = 425
Score = 582 bits (1501), Expect = e-164, Method: Composition-based stats.
Identities = 274/403 (67%), Positives = 335/403 (83%), Gaps = 1/403 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
++I+V P+VE+DGDE TR+IW+ IK++L+LP++DV+LKYYDLSI RD T+DQVT D++
Sbjct: 20 ARIRVKTPVVELDGDEMTRIIWERIKQQLVLPHVDVELKYYDLSITSRDATSDQVTVDAA 79
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
+A +YGV VKCATITPDEAR++EF LK+MW+SPNGTIRNILGGTVFREPI+IP+IPRLV
Sbjct: 80 HAIKQYGVGVKCATITPDEARVREFGLKKMWRSPNGTIRNILGGTVFREPIVIPRIPRLV 139
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P WEKPIIIGRHA GDQY+ATD + AG L L F DG L VY+F G +A+A
Sbjct: 140 PGWEKPIIIGRHAHGDQYKATDAVVPGAGTLDLVFRPADGSAPTSLHVYDFAGPG-VALA 198
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT +SI+GFA ASF LAL ++L LF +TKNTILK YD +FK +F+ L+ +YK +F+
Sbjct: 199 MYNTEESIRGFAHASFRLALAKQLNLFLSTKNTILKQYDGRFKDVFEELYQAQYKAEFER 258
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
L I YEHRLIDDMVAQM+KSKGGFI+A+KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDGK
Sbjct: 259 LGIYYEHRLIDDMVAQMVKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGK 318
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
TFESEAAHGTVTRHFR+HQ G+ETSTNSIASIFAWTR + +RG+LDNT DV+ F + LE
Sbjct: 319 TFESEAAHGTVTRHFRQHQAGKETSTNSIASIFAWTRGLAKRGELDNTPDVVNFAHALEA 378
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
AT +TVQ+ G MTKDLAL G+++RS+YV T EFID V RL+
Sbjct: 379 ATTNTVQLDGIMTKDLALACGRSDRSAYVNTNEFIDAVEARLK 421
>ref|XP_504978.1| hypothetical protein [Yarrowia lipolytica]
emb|CAG77785.1| unnamed protein product [Yarrowia lipolytica CLIB122]
Length = 440
Score = 582 bits (1501), Expect = e-164, Method: Composition-based stats.
Identities = 289/403 (71%), Positives = 339/403 (84%), Gaps = 1/403 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +PIVE+DGDE TR+IWK IK+KLILPYLD+DLKYYDL I+ RD+TNDQVT D++
Sbjct: 35 TKIKVKNPIVELDGDEMTRIIWKSIKDKLILPYLDIDLKYYDLGIEYRDQTNDQVTIDAA 94
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KY V VKCATITPDEAR+KEF LK+MW SPNGTIRNILGGTVFREPI+IP +PRLV
Sbjct: 95 EAIKKYQVGVKCATITPDEARVKEFGLKKMWLSPNGTIRNILGGTVFREPIVIPAVPRLV 154
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W++PIIIGRHA GDQY+A D I AG+L L F +G + +KVY + + G+AMA
Sbjct: 155 PGWKEPIIIGRHAHGDQYKAQDAVIPGAGELTLNFKPANGGDEQVIKVYTY-DAPGVAMA 213
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA +SF LAL++KLPL+ +TKNTILK YD +FK IF ++DKEYK+KF A
Sbjct: 214 MYNTDESITGFAYSSFNLALQKKLPLYMSTKNTILKKYDGRFKDIFQEIYDKEYKDKFDA 273
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KSKGGFI+A+KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDGK
Sbjct: 274 AGIWYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGK 333
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
TFESEAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR +IQRG LD T +V KF LEK
Sbjct: 334 TFESEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGLIQRGILDETPEVTKFAEALEK 393
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
AT+DTV G MTKDLAL GKT+RSSYV TEEFID VA RL+
Sbjct: 394 ATVDTVDKDGIMTKDLALAGGKTDRSSYVLTEEFIDAVANRLK 436
>ref|NP_010217.1| Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the
oxidation of isocitrate to alpha-ketoglutarate; not
required for mitochondrial respiration and may function
to divert alpha-ketoglutarate to biosynthetic processes;
Idp1p [Saccharomyces cerevisiae]
sp|P21954|IDHP_YEAST Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP)
gb|AAA34703.1| NADPH-specific isocitrate dehydrogenase
emb|CAA98631.1| IDP1 [Saccharomyces cerevisiae]
gb|EDN60290.1| NADP-dependent isocitrate dehydrogenase [Saccharomyces cerevisiae
YJM789]
Length = 428
Score = 581 bits (1498), Expect = e-164, Method: Composition-based stats.
Identities = 286/410 (69%), Positives = 342/410 (83%), Gaps = 3/410 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
SKIKV P+VE+DGDE TR+IW IK+KLILPYLDVDLKYYDLS++ RD T+D++T+D++
Sbjct: 18 SKIKVKQPVVELDGDEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSDKITQDAA 77
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KYGV +KCATITPDEAR+KEFNL +MWKSPNGTIRNILGGTVFREPI+IP+IPRLV
Sbjct: 78 EAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTVFREPIVIPRIPRLV 137
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDD--GKENIDLKVYEFPKSGGIA 179
P WEKPIIIGRHA GDQY+ATD I G L L + D + LKVY++ K G+A
Sbjct: 138 PRWEKPIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYDY-KGSGVA 196
Query: 180 MAMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKF 239
MAM+NT++SI+GFA +SF+LA+ +KL LF +TKNTILK YD +FK IF +++ +YK KF
Sbjct: 197 MAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYKSKF 256
Query: 240 QALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPD 299
+ L I YEHRLIDDMVAQM+KSKGGFI+A+KNYDGDVQSDIVAQGFGSLGLMTSIL+TPD
Sbjct: 257 EQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPD 316
Query: 300 GKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLL 359
GKTFESEAAHGTVTRH+RK+Q+GEETSTNSIASIFAW+R +++RG+LDNT + KF N+L
Sbjct: 317 GKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFANIL 376
Query: 360 EKATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
E ATL+TVQ G MTKDLAL G RS+YVTTEEF+D V KRLQ + S
Sbjct: 377 ESATLNTVQQDGIMTKDLALACGNNERSAYVTTEEFLDAVEKRLQKEIKS 426
>ref|XP_001527573.1| isocitrate dehydrogenase peroxisomal [Lodderomyces elongisporus
NRRL YB-4239]
gb|EDK41915.1| isocitrate dehydrogenase peroxisomal [Lodderomyces elongisporus
NRRL YB-4239]
Length = 412
Score = 580 bits (1496), Expect = e-164, Method: Composition-based stats.
Identities = 287/401 (71%), Positives = 339/401 (84%), Gaps = 1/401 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TR+IW+ IK+KLILPYLD+DLKYYDL I+ RD+T+D+VT D++
Sbjct: 6 KIKVKNPIVEMDGDEMTRIIWQFIKDKLILPYLDIDLKYYDLGIEYRDQTDDKVTTDAAE 65
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A LKYGV VKCATITPDE R++EF LK+MW SPNGT+RNILGGTVFREPI+I IPR+VP
Sbjct: 66 AILKYGVGVKCATITPDEQRVEEFKLKKMWLSPNGTLRNILGGTVFREPIVIENIPRIVP 125
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
WEKPIIIGRHAFGDQY+ATDI + KAG+L+L F DG E ++ VY F + G+ ++M
Sbjct: 126 AWEKPIIIGRHAFGDQYKATDIIVPKAGELKLVFKPKDGSEIVEYPVYNF-EGPGVGLSM 184
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT+ SI FA++SF+LAL+RKL LF +TKNTILK YD +FK IF+NL+ +YK++
Sbjct: 185 YNTDASISDFAESSFQLALERKLNLFSSTKNTILKKYDGRFKDIFENLYATKYKKQMDEA 244
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVAQMLKSKGG+IIAMKNYDGDVQSDIVAQGFGSLGLMTS+L+TPDGK
Sbjct: 245 GIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDGKA 304
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
FESEAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR +IQRGKLD T +V+KF LEKA
Sbjct: 305 FESEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGLIQRGKLDKTPEVVKFAEDLEKA 364
Query: 363 TLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRL 403
+DTV + GKMTKDLAL GKT R SYVTTEEFID VA RL
Sbjct: 365 VIDTVAIDGKMTKDLALAQGKTARESYVTTEEFIDNVASRL 405
>ref|XP_460289.1| hypothetical protein DEHA0E24134g [Debaryomyces hansenii CBS767]
emb|CAG88573.1| unnamed protein product [Debaryomyces hansenii CBS767]
Length = 410
Score = 579 bits (1492), Expect = e-163, Method: Composition-based stats.
Identities = 289/402 (71%), Positives = 338/402 (84%), Gaps = 1/402 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV PIVEMDGDE TR+IWK IK+KLI PYLDVDLKYYDL I+ R++T+D+VT D++
Sbjct: 4 NKIKVDQPIVEMDGDEMTRIIWKFIKDKLIFPYLDVDLKYYDLGIEYRNQTDDKVTTDAA 63
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A LKY V VKCATITPDEAR++EF LK+MW SPNGT+RNILGGTVFREPI+I IPR+V
Sbjct: 64 EAILKYQVGVKCATITPDEARVEEFKLKKMWLSPNGTLRNILGGTVFREPIVIDNIPRIV 123
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P WE PIIIGRHAFGDQY+ATD+ I KAG+L L F DG VY + + G+A+A
Sbjct: 124 PQWESPIIIGRHAFGDQYKATDVVIPKAGQLELVFKPADGSATEVYPVYNY-DAPGVALA 182
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT SI FA++SF++AL RKL LF +TKNTILK YD +FK IF++L++K+YK++F+
Sbjct: 183 MYNTEKSITDFAESSFKMALDRKLILFSSTKNTILKKYDGRFKDIFEDLYEKKYKKQFEE 242
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQMLKSKGG+IIAMKNYDGDVQSDIVAQGFGSLGLMTS+L+TPDGK
Sbjct: 243 AGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDGK 302
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FE+EAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR IIQRGKLDN DV+KFG LEK
Sbjct: 303 AFEAEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGIIQRGKLDNNADVVKFGESLEK 362
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRL 403
AT+DTV + MTKDLAL GKT RSSYVTTEEFID VAKRL
Sbjct: 363 ATIDTVALDNVMTKDLALAQGKTERSSYVTTEEFIDAVAKRL 404
>ref|XP_001528456.1| isocitrate dehydrogenase, mitochondrial precursor [Lodderomyces
elongisporus NRRL YB-4239]
gb|EDK42798.1| isocitrate dehydrogenase, mitochondrial precursor [Lodderomyces
elongisporus NRRL YB-4239]
Length = 430
Score = 577 bits (1487), Expect = e-163, Method: Composition-based stats.
Identities = 277/403 (68%), Positives = 340/403 (84%), Gaps = 1/403 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KI V +PIVE+DGDE TR+IW+ IK+ LI PYL+VDLKYYDL I+ RD TNDQ+T D++
Sbjct: 28 NKITVKNPIVELDGDEMTRIIWQKIKDDLIHPYLNVDLKYYDLGIESRDATNDQITVDAA 87
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
+A KYGV VKCATITPDEAR+KEF LK+MW SPNGTIRNILGGTVFRE IIIP IPRLV
Sbjct: 88 HAIQKYGVGVKCATITPDEARVKEFGLKKMWLSPNGTIRNILGGTVFRESIIIPCIPRLV 147
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W++PI+IGRHAFGDQY+ATD+ I++ G L L+F+ D+G E KVY++ G+ +A
Sbjct: 148 PGWKEPIVIGRHAFGDQYKATDLVIQEPGTLELRFTPDNGGETQTHKVYQY-SGPGVGLA 206
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI+GFA ASF++A+ + LPL+ +TKNTILK YD +FK IF ++D EYK++F+
Sbjct: 207 MYNTDESIRGFAHASFKMAINKGLPLYMSTKNTILKKYDGRFKDIFQEIYDSEYKQEFEK 266
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KSKGGF++A+KNYDGDVQSDIVAQGFGSLGLMTS L+TPDG
Sbjct: 267 KGIWYEHRLIDDMVAQMIKSKGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSALMTPDGS 326
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
+ESEAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR I QRG+LDNT +V++F N LEK
Sbjct: 327 AYESEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGIAQRGRLDNTPEVVEFANKLEK 386
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
AT+DTVQ MTKDLAL +GKT+RSSYVTT EF+D VA RL+
Sbjct: 387 ATIDTVQEDRIMTKDLALAMGKTDRSSYVTTTEFLDAVANRLK 429
>ref|XP_713421.1| cytosolic NADP-specific isocitrate dehydrogenase [Candida albicans
SC5314]
gb|EAK94305.1| hypothetical protein CaO19.3733 [Candida albicans SC5314]
Length = 412
Score = 577 bits (1486), Expect = e-163, Method: Composition-based stats.
Identities = 287/403 (71%), Positives = 338/403 (83%), Gaps = 1/403 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KIKV +PIVEMDGDE TR+IW+ IK+KLI PYLDVDLKYYDL I+ RD+T+D+VT D+
Sbjct: 4 IQKIKVKNPIVEMDGDEMTRIIWQFIKDKLITPYLDVDLKYYDLGIEYRDQTDDKVTTDA 63
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A LKYGV VKCATITPDEAR+KEFNLK+MW SPNGT+RNILGGTVFREPI+I IPR+
Sbjct: 64 ANAILKYGVGVKCATITPDEARVKEFNLKKMWLSPNGTLRNILGGTVFREPIVIDNIPRI 123
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP WEKPIIIGRHAFGDQY+ATDI + AG+L+L F DG E + VY F + G+ +
Sbjct: 124 VPSWEKPIIIGRHAFGDQYKATDIVVPGAGELKLVFKPKDGGEIQEYPVYNF-EGPGVGL 182
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+M+NT+ SI+ FA++SF+LA++RKL LF +TKNTILK YD +FK IF+ L+ +YK K
Sbjct: 183 SMYNTDASIQDFAESSFQLAIERKLNLFSSTKNTILKKYDGRFKDIFEGLYASKYKTKMD 242
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
L I YEHRLIDDMVAQMLKSKGG+IIAMKNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 243 ELGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDG 302
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
K FESEAAHGTVTRH+R+HQ+G+ETSTNSIASI+AWTR +IQRGKLD T +V+KF LE
Sbjct: 303 KAFESEAAHGTVTRHYRQHQQGKETSTNSIASIYAWTRGLIQRGKLDETPEVVKFAEDLE 362
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRL 403
KA +DTV MTKDLAL GKT+RSSYVTTEEFID VA RL
Sbjct: 363 KAIIDTVSKDNIMTKDLALTQGKTDRSSYVTTEEFIDAVANRL 405
>ref|XP_001383685.1| Isocitrate dehydrogenase [NADP] peroxisomal (Oxalosuccinate
decarboxylase) (IDH) (PS-NADP-IDH) (CtIDP2) [Pichia
stipitis CBS 6054]
gb|ABN65656.1| Isocitrate dehydrogenase [NADP] peroxisomal (Oxalosuccinate
decarboxylase) (IDH) (PS-NADP-IDH) (CtIDP2) [Pichia
stipitis CBS 6054]
Length = 410
Score = 575 bits (1482), Expect = e-162, Method: Composition-based stats.
Identities = 283/403 (70%), Positives = 340/403 (84%), Gaps = 1/403 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+SKI V +PIVEMDGDEQTR+IW+ IK+KLILPYL++DLKYYDL I+ RD+T+D+VT D+
Sbjct: 3 ISKITVKNPIVEMDGDEQTRIIWQFIKDKLILPYLNIDLKYYDLGIEYRDQTDDKVTTDA 62
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A L+YGV VKCATITPDEAR+KEFNLK+MW SPNGT+RNILGGTVFREPI+I IPR+
Sbjct: 63 AKAILEYGVGVKCATITPDEARVKEFNLKKMWLSPNGTLRNILGGTVFREPIVIDNIPRI 122
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP WEKPIIIGRHAFGDQY+ATDI + +AG++ L F DG + VY F + G+A+
Sbjct: 123 VPQWEKPIIIGRHAFGDQYKATDIIVPQAGEVSLIFKPADGSPAQEYPVYNF-QGAGVAL 181
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+NT++SI FA++SF LAL+RKL LF +TKNTILK YD +FK IF+ L+ +Y++ F+
Sbjct: 182 AMYNTDESITDFAESSFRLALERKLNLFSSTKNTILKKYDGRFKDIFEGLYASKYQKLFE 241
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQMLKSKGG+IIAMKNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 242 AEGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 301
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
K FE+EAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR +IQRGKLD T +V +F LE
Sbjct: 302 KAFEAEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGLIQRGKLDKTPEVSEFAEKLE 361
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRL 403
+AT++TV MTKDL+L GKT RSSYVTTEEFID VA RL
Sbjct: 362 QATIETVSKDNIMTKDLSLAQGKTERSSYVTTEEFIDAVAARL 404
>ref|XP_446953.1| unnamed protein product [Candida glabrata]
emb|CAG59886.1| unnamed protein product [Candida glabrata CBS 138]
Length = 418
Score = 574 bits (1480), Expect = e-162, Method: Composition-based stats.
Identities = 298/403 (73%), Positives = 353/403 (87%), Gaps = 2/403 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVEMDGDE TRVIW ++K+KLI PYLDVDLKYYDLSIQ RD T D+VT D++
Sbjct: 4 KIKVKNPIVEMDGDEMTRVIWGMVKDKLIYPYLDVDLKYYDLSIQHRDETEDRVTVDAAE 63
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
ATLK+GVA+KCATITPDEARMKEF+LK+MWKSPNGTIRNILGGTVFREPIIIP+IPR+VP
Sbjct: 64 ATLKHGVAIKCATITPDEARMKEFHLKKMWKSPNGTIRNILGGTVFREPIIIPRIPRIVP 123
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENID-LKVYEFPKSGGIAMA 181
W KPIIIGRHAFGDQY+A+D IK+ GKL L F+ G+ N +KVY++ KS G+A+A
Sbjct: 124 TWNKPIIIGRHAFGDQYKASDAVIKEPGKLELVFTPASGQGNPKTIKVYDY-KSPGVALA 182
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA+ASFELA+KRKLPLFFTTKNTILK YD +FK IF ++D++YK KF+
Sbjct: 183 MYNTDESITGFARASFELAIKRKLPLFFTTKNTILKKYDGRFKDIFQKMYDEDYKGKFKE 242
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
L I+YEHRLIDDMVAQM+KSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTS L+TPDGK
Sbjct: 243 LGISYEHRLIDDMVAQMIKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSTLLTPDGK 302
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FESEAAHGTVTRH+R++Q+G+ETSTNSIA+IFAW++ II RGK+D T DV FG +LE+
Sbjct: 303 IFESEAAHGTVTRHYRQYQKGKETSTNSIATIFAWSQGIIHRGKVDQTPDVRLFGEILER 362
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
+T+DTVQ+ G MTKDLAL+LGKT R Y +TEEFID VA+RL+
Sbjct: 363 STIDTVQIDGIMTKDLALILGKTERKDYASTEEFIDAVARRLK 405
>ref|XP_001485076.1| isocitrate dehydrogenase peroxisomal [Pichia guilliermondii ATCC
6260]
gb|EDK38707.1| isocitrate dehydrogenase peroxisomal [Pichia guilliermondii ATCC
6260]
Length = 409
Score = 574 bits (1479), Expect = e-162, Method: Composition-based stats.
Identities = 285/402 (70%), Positives = 339/402 (84%), Gaps = 1/402 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
SKI V +PIVEMDGDE TR+IWK IK+KLI PYLDVDLKYYDL I+ RD+T+D+VT D++
Sbjct: 3 SKITVKNPIVEMDGDEMTRIIWKFIKDKLITPYLDVDLKYYDLGIEYRDQTDDKVTTDAA 62
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A LKYGV VKCATITPDEAR+KEFNLK+MW SPNGT+RNILGGTVFREPI+I IPR+V
Sbjct: 63 DAILKYGVGVKCATITPDEARVKEFNLKKMWLSPNGTLRNILGGTVFREPIVIDNIPRVV 122
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P WE+PIIIGRHA+GDQY+ATD+ I +AG+L L F DG E V+ + K+ G+A++
Sbjct: 123 PTWEQPIIIGRHAYGDQYKATDVVIPQAGELSLVFKPADGSETKTYPVFNY-KAPGVALS 181
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI FA++SF+LAL+RK+ LF +TKNTILK YD +FK IF+ L++ +YK+ F
Sbjct: 182 MYNTDESITDFAESSFQLALQRKMNLFSSTKNTILKRYDGRFKDIFEGLYESKYKKLFDE 241
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQMLKSKGG+IIAMKNYDGDVQSDIVAQGFGSLGLMTS+L+TPDGK
Sbjct: 242 AGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDGK 301
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FE+EAAHGTVTRH+R+HQ+G+ETSTNSIASI+AWTR IIQRG LD T +V+KFG LEK
Sbjct: 302 AFEAEAAHGTVTRHYRQHQQGKETSTNSIASIYAWTRGIIQRGILDETPEVVKFGEALEK 361
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRL 403
A +DTV G MTKDLAL GKT+RSSYVTTEEFID V RL
Sbjct: 362 AVIDTVSKDGIMTKDLALTQGKTDRSSYVTTEEFIDAVKVRL 403
>sp|O13294|IDH2_CANTR Isocitrate dehydrogenase [NADP] peroxisomal (Oxalosuccinate
decarboxylase) (IDH) (PS-NADP-IDH) (CtIDP2)
dbj|BAA22846.1| NADP-linked isocitrate dehydrogenase [Candida tropicalis]
Length = 411
Score = 573 bits (1477), Expect = e-162, Method: Composition-based stats.
Identities = 283/403 (70%), Positives = 338/403 (83%), Gaps = 1/403 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KI V +PIVEMDGDE TR+IW+ IK+KLILPYL+VDLKYYDL I+ RD+T+D+VT D+
Sbjct: 4 IQKITVKNPIVEMDGDEMTRIIWQFIKDKLILPYLNVDLKYYDLGIEYRDKTDDKVTTDA 63
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A L+YGV VKCATITPDEAR+KEFNLK+MW SPNGT+RN++GGTVFREPI+I IPR+
Sbjct: 64 AEAILQYGVGVKCATITPDEARVKEFNLKKMWLSPNGTLRNVIGGTVFREPIVIDNIPRI 123
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP WEKPIIIGRHAFGDQY+ATD+ I AG L+L F DG E + VY+F G+A+
Sbjct: 124 VPSWEKPIIIGRHAFGDQYKATDVVIPAAGDLKLVFKPKDGGEVQEFPVYQF-DGPGVAL 182
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+M+NT+ SI FA++SF+LA++RKL LF +TKNTILK YD +FK IF+ L+ +YK K
Sbjct: 183 SMYNTDASITDFAESSFQLAIERKLNLFSSTKNTILKKYDGKFKDIFEGLYASKYKTKMD 242
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
L I YEHRLIDDMVAQMLKSKGG+IIAMKNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 243 ELGIWYEHRLIDDMVAQMLKSKGGYIIAMKNYDGDVQSDIVAQGFGSLGLMTSVLVTPDG 302
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
K FESEAAHGTVTRH+R+HQ+G+ETSTNSIASI+AWTR +IQRGKLD+T +V+KF LE
Sbjct: 303 KAFESEAAHGTVTRHYRQHQQGKETSTNSIASIYAWTRGLIQRGKLDDTPEVVKFAEELE 362
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRL 403
KA ++TV MTKDLAL GKT+RSSYVTTEEFID VA RL
Sbjct: 363 KAVIETVSKDNIMTKDLALTQGKTDRSSYVTTEEFIDGVANRL 405
>ref|XP_459772.1| hypothetical protein DEHA0E11286g [Debaryomyces hansenii CBS767]
emb|CAG88011.1| unnamed protein product [Debaryomyces hansenii CBS767]
Length = 431
Score = 570 bits (1469), Expect = e-161, Method: Composition-based stats.
Identities = 275/407 (67%), Positives = 343/407 (84%), Gaps = 1/407 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KIKV +PIVE+DGDE TR+IW+ IK+KLI PYLDVDLKYYDL I+ RD+T+DQ+T D+
Sbjct: 24 LDKIKVKNPIVELDGDEMTRIIWQRIKDKLINPYLDVDLKYYDLGIESRDKTDDQITIDA 83
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDE+R++EFNLK+MW SPNGTIRNILGGTVFRE IIIP+IPRL
Sbjct: 84 ANAIKEYGVGVKCATITPDESRVEEFNLKKMWLSPNGTIRNILGGTVFREAIIIPRIPRL 143
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W++PI+IGRHA GDQY+ATD+ I + GKL + F+ ++G VY++ K G+ +
Sbjct: 144 VPGWKEPIVIGRHAHGDQYKATDLVINEPGKLEMTFTPENGGAPETRTVYDY-KGPGVGL 202
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+NT++SI GFA +SF++AL +KLPL+ +TKNTILK YD +FK IF +++ YK++F+
Sbjct: 203 AMYNTDESIIGFAHSSFKMALTKKLPLYLSTKNTILKKYDGRFKDIFHEIYESTYKKEFE 262
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
I YEHRLIDDMVAQM+KSKGGF++A+KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 263 TNNIWYEHRLIDDMVAQMIKSKGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 322
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFESEAAHGTVTRHFR+HQ+G+ETSTNSIASIFAWTR I QRG+LD+T DV+KF ++E
Sbjct: 323 KTFESEAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGIAQRGRLDDTPDVVKFAEIVE 382
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
KAT DTVQ G MTKDLAL LG+T+R SYVTT EF+D V+ +LQ +
Sbjct: 383 KATFDTVQEDGIMTKDLALALGRTDRESYVTTTEFLDAVSDKLQKQV 429
>ref|XP_001384028.1| Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (CtIDP1) [Pichia stipitis CBS 6054]
gb|ABN65999.1| Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (CtIDP1) [Pichia stipitis CBS 6054]
Length = 434
Score = 570 bits (1469), Expect = e-161, Method: Composition-based stats.
Identities = 271/404 (67%), Positives = 341/404 (84%), Gaps = 1/404 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
++KIKV +PIVE+DGDE TR+IW+ IK+KLI PYLD+DLKYYDL I+ RD T+D++T D+
Sbjct: 27 LAKIKVKNPIVELDGDEMTRIIWQRIKDKLINPYLDIDLKYYDLGIESRDATDDKITIDA 86
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDE R++EF LK+MW SPNGTIRNILGGTVFRE IIIP++PRL
Sbjct: 87 ANAIKEYGVGVKCATITPDEQRVEEFGLKKMWLSPNGTIRNILGGTVFRESIIIPRVPRL 146
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
+P W++PI+IGRHA GDQY+ATD+ I + GK+ L F+ +G VY++ KS G+A+
Sbjct: 147 IPGWKEPIVIGRHAHGDQYKATDLVISEPGKVELVFTPANGGAPETRTVYDY-KSPGVAL 205
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+NT++SI+GFA +SF++AL +KLPL+ +TKNTILK YD +FK IF +++ EY +F+
Sbjct: 206 AMYNTDESIRGFAHSSFKMALTKKLPLYMSTKNTILKKYDGRFKDIFQEIYEAEYASQFK 265
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A + YEHRLIDDMVAQM+KSKGGF++A+KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 266 AAGLWYEHRLIDDMVAQMIKSKGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 325
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
K FESEAAHGTVTRH+R+HQ+G+ETSTNSIASIFAW+R I QRG+LDNT +V+ F N LE
Sbjct: 326 KAFESEAAHGTVTRHYRQHQQGKETSTNSIASIFAWSRGIAQRGRLDNTPEVVDFANTLE 385
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
KATLDTVQ G MTKDLAL GKT+R+SYVTT EF+D VA +L+
Sbjct: 386 KATLDTVQEDGIMTKDLALACGKTDRASYVTTTEFLDAVADKLK 429
>ref|XP_001226620.1| conserved hypothetical protein [Chaetomium globosum CBS 148.51]
gb|EAQ84679.1| conserved hypothetical protein [Chaetomium globosum CBS 148.51]
Length = 469
Score = 568 bits (1464), Expect = e-160, Method: Composition-based stats.
Identities = 273/406 (67%), Positives = 328/406 (80%), Gaps = 1/406 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TRVIWK IKEK I PYLDVDLKYYDL ++ RD TNDQVT D++
Sbjct: 61 AKIKVKNPVVELDGDEMTRVIWKDIKEKFIFPYLDVDLKYYDLGLEYRDETNDQVTLDAA 120
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KY V VKCATITPDEAR++EF LK+MW SPNGTIRN LGGTVFREPI+IP+IPRLV
Sbjct: 121 EAIKKYSVGVKCATITPDEARVEEFKLKQMWLSPNGTIRNALGGTVFREPIVIPRIPRLV 180
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPIIIGRHAFGDQYRA D+ + GKL + ++ G E +++V++F GG+A
Sbjct: 181 PGWKKPIIIGRHAFGDQYRAKDLVVPGPGKLSMVYTPAGG-EPQEIEVFQFKNGGGVAQT 239
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT++SI GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF L+D YK +F+A
Sbjct: 240 QYNTDESITGFAHASFKLALDKGLPLYMSTKNTILKKYDGRFKDIFQELYDGGYKAQFEA 299
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS GG+I+A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGK
Sbjct: 300 KGIWYEHRLIDDMVAQMIKSTGGYIMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGK 359
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
TFESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T +V+ F LE+
Sbjct: 360 TFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPEVVAFAEGLER 419
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
A +DTV + G MTKDLAL GKT R YVTT E++ V +RL+ +
Sbjct: 420 ACIDTVDIDGIMTKDLALACGKTAREDYVTTSEYLSAVERRLKQSL 465
>ref|XP_710919.1| NADP-specific isocitrate dehydrogenase [Candida albicans SC5314]
ref|XP_710904.1| NADP-specific isocitrate dehydrogenase [Candida albicans SC5314]
gb|EAK91661.1| hypothetical protein CaO19.12678 [Candida albicans SC5314]
gb|EAK91676.1| hypothetical protein CaO19.5211 [Candida albicans SC5314]
Length = 433
Score = 567 bits (1461), Expect = e-160, Method: Composition-based stats.
Identities = 271/404 (67%), Positives = 341/404 (84%), Gaps = 1/404 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KIKV +PIVE+DGDE TR+IW+ IK++LILPYLDV+LKYYDL I+ RD TNDQ+T D+
Sbjct: 30 LDKIKVKNPIVELDGDEMTRIIWQKIKDQLILPYLDVNLKYYDLGIESRDATNDQITIDA 89
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A ++GV VKCATITPDEAR+KEFNLK+MW SPNGTIRNILGGTVFRE IIIP IPRL
Sbjct: 90 ANAIKEHGVGVKCATITPDEARVKEFNLKKMWLSPNGTIRNILGGTVFRESIIIPCIPRL 149
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
+P W++PI+IGRHAFGDQY+ATD+ I + GKL L+F+ ++G E KVY++ G+ +
Sbjct: 150 IPGWKEPIVIGRHAFGDQYKATDLVISEPGKLELRFTPENGGETQTHKVYDY-TGPGVGL 208
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+NT++SI GFA+ASF +AL + LPL+ +TKNTILK YD +FK IF ++++ EY +F+
Sbjct: 209 AMYNTDESISGFARASFNMALSKNLPLYMSTKNTILKKYDGRFKDIFQDIYENEYASEFE 268
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
+ YEHRLIDDMVAQM+KSKGGF++A+KNYDGDVQSDIVAQGFGSLGLMTS L+TPDG
Sbjct: 269 KKGLWYEHRLIDDMVAQMIKSKGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSALMTPDG 328
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
K +E+EAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR + QRG+LD T +V+ F + LE
Sbjct: 329 KAYEAEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGLAQRGRLDETPEVVDFADKLE 388
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
KAT+DTV+V MTKDLAL +GKT+RS+YVTT EF+D VA RL+
Sbjct: 389 KATIDTVEVDRIMTKDLALAMGKTDRSAYVTTTEFLDAVADRLK 432
>ref|XP_001903959.1| unnamed protein product [Podospora anserina]
emb|CAP61736.1| unnamed protein product [Podospora anserina]
Length = 461
Score = 567 bits (1460), Expect = e-160, Method: Composition-based stats.
Identities = 272/406 (66%), Positives = 330/406 (81%), Gaps = 1/406 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TRVIW+ IK+K I PYLD+DLKYYDL ++ RD+TNDQVT D++
Sbjct: 53 AKIKVKNPVVELDGDEMTRVIWQDIKDKFITPYLDIDLKYYDLGLEYRDQTNDQVTIDAA 112
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KY V VKCATITPDEAR++EF LK+MW SPNGTIRN LGGTVFREPI+IP++PRLV
Sbjct: 113 EAIKKYSVGVKCATITPDEARVEEFKLKQMWLSPNGTIRNALGGTVFREPIVIPRVPRLV 172
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPIIIGRHAFGDQYRA D GKL + ++ + G E +++VY+F GG+A
Sbjct: 173 PGWKKPIIIGRHAFGDQYRAKDFVAPGPGKLSMVYTPEGG-EPQEIEVYKFQGGGGVAQT 231
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT++SI GFA ASF+LA+ + LPL+ +TKNTILK YD +FK IF L+D +YKE F+A
Sbjct: 232 QYNTDESITGFAHASFKLAIDKGLPLYMSTKNTILKKYDGRFKDIFQELYDTQYKEAFEA 291
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS GG+I+A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGK
Sbjct: 292 KGIWYEHRLIDDMVAQMIKSSGGYIMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGK 351
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
TFESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD+T +V+ F LEK
Sbjct: 352 TFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDDTPEVVAFAEALEK 411
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
A +DTV V G MTKDLAL GKT R YVTT E++ V +RL+ +
Sbjct: 412 ACIDTVDVDGIMTKDLALACGKTGREDYVTTSEYMVAVERRLKQSL 457
>sp|O13285|IDH1_CANTR Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (CtIDP1)
dbj|BAA22945.1| mitochondrial NADP-linked isocitrate dehydrogenase [Candida
tropicalis]
Length = 430
Score = 566 bits (1459), Expect = e-159, Method: Composition-based stats.
Identities = 272/402 (67%), Positives = 338/402 (84%), Gaps = 1/402 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVE+DGDE TR+IW+ IK++LILPYLDVDLKYYDL I+ RD T+DQ+T D++
Sbjct: 29 KIKVKNPIVELDGDEMTRIIWQKIKDQLILPYLDVDLKYYDLGIESRDATDDQITIDAAN 88
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A +YGV VKCATITPDEAR+KEF+LK+MW SPNGTIRNILGGTVFRE IIIP IPRL+P
Sbjct: 89 AIKEYGVGVKCATITPDEARVKEFHLKKMWLSPNGTIRNILGGTVFRESIIIPCIPRLIP 148
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
WEKPI+IGRHAFGDQY+ATD+ I + G+L L+F+ G E KVY++ G+ +AM
Sbjct: 149 GWEKPIVIGRHAFGDQYKATDLVINEPGRLELRFTPASGGEAQTQKVYDY-TGPGVGLAM 207
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA ASF++AL + LPL+ +TKNTILK YD +FK IF +++++Y +F+
Sbjct: 208 YNTDESITGFAHASFKMALAKGLPLYMSTKNTILKKYDGRFKDIFQQIYEQDYAAEFEKQ 267
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
+ YEHRLIDDMVAQM+KSKGGF++A+KNYDGDVQSDIVAQGFGSLGLMTS L+TPDGK
Sbjct: 268 GLWYEHRLIDDMVAQMIKSKGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSALMTPDGKA 327
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
+E+EAAHGTVTRH+R+HQ+G+ETSTNSIASIFAWTR + QRGKLD T DV+ F + LE+A
Sbjct: 328 YEAEAAHGTVTRHYRQHQQGKETSTNSIASIFAWTRGLAQRGKLDETPDVVDFASKLEQA 387
Query: 363 TLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
T+DTV+V MTKDLAL +GKT+RS+YVTT EF+D VA RL+
Sbjct: 388 TIDTVEVDRIMTKDLALAMGKTDRSAYVTTTEFLDAVADRLK 429
>ref|XP_955850.1| hypothetical protein NCU03857 [Neurospora crassa OR74A]
gb|EAA26614.1| hypothetical protein NCU03857 [Neurospora crassa OR74A]
Length = 462
Score = 565 bits (1455), Expect = e-159, Method: Composition-based stats.
Identities = 265/405 (65%), Positives = 333/405 (82%), Gaps = 1/405 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +P+VE+DGDE TR+IW+ IKEK I P+LD+DLKYYDL ++ RD+TNDQVT D++
Sbjct: 55 KIKVKNPVVELDGDEMTRIIWQDIKEKFIYPFLDIDLKYYDLGLEYRDQTNDQVTIDAAE 114
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A KY V VKCATITPDE+R++EF LK+MW SPNGTIRN LGGTVFREPI+IP++PRLVP
Sbjct: 115 AIKKYSVGVKCATITPDESRVEEFKLKQMWLSPNGTIRNALGGTVFREPIVIPRVPRLVP 174
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W+KPIIIGRHAFGDQYRA D+ GKL++ ++ + G+ + + V+++ GG+A
Sbjct: 175 GWKKPIIIGRHAFGDQYRAKDLVAPGPGKLQMVYTPEGGEPQV-IDVFDYKNGGGVAQTQ 233
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI+GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF ++D +YKE F+A
Sbjct: 234 YNTDESIEGFAHASFKLALDKGLPLYMSTKNTILKKYDGRFKDIFQQIYDTQYKEAFEAK 293
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQM+KS GG+I+A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGKT
Sbjct: 294 KIWYEHRLIDDMVAQMIKSSGGYIMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGKT 353
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
FESEAAHGTVTRH+R+HQ+G +TSTN IASIFAWTR ++QRGKLDNT ++I F LEKA
Sbjct: 354 FESEAAHGTVTRHYREHQKGNQTSTNPIASIFAWTRGLVQRGKLDNTPELIAFAEALEKA 413
Query: 363 TLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
+DTV + G MTKDLAL GKT R +VTT E++ V +RL++ +
Sbjct: 414 CIDTVDIDGIMTKDLALACGKTGREDWVTTSEYMAAVERRLKSTL 458
>ref|XP_001484278.1| isocitrate dehydrogenase, mitochondrial precursor [Pichia
guilliermondii ATCC 6260]
gb|EDK39561.1| isocitrate dehydrogenase, mitochondrial precursor [Pichia
guilliermondii ATCC 6260]
Length = 437
Score = 563 bits (1452), Expect = e-159, Method: Composition-based stats.
Identities = 269/404 (66%), Positives = 338/404 (83%), Gaps = 2/404 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
SKIKV +PIVE+DGDE TR+IW+ IK+KLI PYLDVDLKYYDL I+ RD+T+DQ+T D++
Sbjct: 34 SKIKVKNPIVELDGDEMTRIIWQRIKDKLIHPYLDVDLKYYDLGIEARDKTDDQITIDAA 93
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
+A KYGV VKCATITPDEAR+KEF LK+MW SPNGTIRNILGGTVFRE I+IP++PRLV
Sbjct: 94 HAIQKYGVGVKCATITPDEARVKEFGLKKMWLSPNGTIRNILGGTVFRESIVIPRVPRLV 153
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+ PI+IGRHA GDQY+ATD+ + GKL L+F+ DG E+ VY++ + G+ +A
Sbjct: 154 PGWKLPIVIGRHAHGDQYKATDLVVSGPGKLELKFTPKDGGESETRVVYDY-QGPGVGLA 212
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI+GFA +SF++AL +KLPL+ TKNTILK YD +FK IF ++ +EY+ +F+A
Sbjct: 213 MYNTDESIRGFAHSSFKMALSKKLPLYMLTKNTILKKYDGRFKDIFAEVY-QEYQSEFEA 271
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
+ YEHRLIDDMVAQM+KS+GGF++A+KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDGK
Sbjct: 272 QGLWYEHRLIDDMVAQMMKSQGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDGK 331
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FESEAAHGTVTRHFR+HQ+G+ETSTNSIASIFAWTR + QRG+LDNT +V++F +EK
Sbjct: 332 AFESEAAHGTVTRHFRQHQQGKETSTNSIASIFAWTRGLAQRGRLDNTPEVVEFAERVEK 391
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQN 405
AT+DTV G MTKDLA+ G +RS+YVTT EF+D VA + N
Sbjct: 392 ATVDTVDKQGIMTKDLAIACGNLDRSAYVTTTEFLDAVADSVAN 435
>gb|AAK76730.1| mitochondrial NADP-dependent isocitrate dehydrogenase [Aspergillus
nidulans]
Length = 493
Score = 563 bits (1451), Expect = e-159, Method: Composition-based stats.
Identities = 270/404 (66%), Positives = 331/404 (81%), Gaps = 2/404 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KIKV +P+VE+DGDE TR+IWK I+EKLILP+LD+DLKYYDL ++ RD+T+D+VT +S
Sbjct: 85 VQKIKVKNPVVELDGDEMTRIIWKEIREKLILPFLDIDLKYYDLGLEYRDQTDDKVTTES 144
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRL
Sbjct: 145 AEAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRL 204
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPIIIGRHAFGDQYRATD I GKL L ++ + G+ +KV++FP GG+
Sbjct: 205 VPGWTKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPEGGQPEA-IKVFDFP-GGGVTQ 262
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+NT++SI+GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF +F+ +YK++F
Sbjct: 263 TQYNTDESIRGFAHASFKLALTKGLPLYMSTKNTILKKYDGRFKDIFQEIFESDYKKEFD 322
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQM+KS+GGFI+A+KNYDGDVQSDIVAQGFGSLGLMTS LITPDG
Sbjct: 323 AKGIWYEHRLIDDMVAQMIKSEGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSTLITPDG 382
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+ FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+KF LE
Sbjct: 383 QAFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVKFAEELE 442
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
+A +D V G MTKDLAL G+ R ++VTT E++ V +RL+
Sbjct: 443 RACIDVVNEEGIMTKDLALSCGRKERDAWVTTREYMAAVERRLR 486
>ref|XP_001593497.1| hypothetical protein SS1G_04924 [Sclerotinia sclerotiorum 1980]
gb|EDO02448.1| hypothetical protein SS1G_04924 [Sclerotinia sclerotiorum 1980]
Length = 450
Score = 563 bits (1450), Expect = e-158, Method: Composition-based stats.
Identities = 271/405 (66%), Positives = 323/405 (79%), Gaps = 1/405 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +PIVE+DGDE TR+IWK IK+K I PYLDVDLKYYDL ++ RD TNDQVT D++
Sbjct: 43 KIKVKNPIVELDGDEMTRIIWKDIKDKFIHPYLDVDLKYYDLGLEYRDETNDQVTIDAAE 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A KY V VKCATITPDEAR+KEFNLK+MW SPNGTIRN LGGTVFREPI+IP+IPRLVP
Sbjct: 103 AIQKYSVGVKCATITPDEARVKEFNLKQMWLSPNGTIRNHLGGTVFREPIVIPRIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W+KPIIIGRHAFGDQYRA D+ + G L + F+ D G + VY F GG+A
Sbjct: 163 GWKKPIIIGRHAFGDQYRAKDMVVPGPGTLTMTFTPDGGAPT-ETVVYNFKSGGGVAQTQ 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF +FDKEYK +F
Sbjct: 222 YNTDESISGFAHASFKLALSKGLPLYMSTKNTILKKYDGRFKDIFQEIFDKEYKPQFDEK 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQM+KS GG+++A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGKT
Sbjct: 282 KIWYEHRLIDDMVAQMMKSSGGYVMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
FESEAAHGTVTRH+R+HQ+G TSTN IASIFAWTR ++QRG LDNT +V+ F LE+A
Sbjct: 342 FESEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLVQRGTLDNTPEVVAFAESLEQA 401
Query: 363 TLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
+D V G MTKDLAL G T + YVTT E+++ V KR++ ++
Sbjct: 402 CIDVVDKEGIMTKDLALACGNTGKDDYVTTGEYLEAVEKRMKGLL 446
>ref|YP_002761841.1| NADP-dependent isocitrate dehydrogenase [Gemmatimonas aurantiaca
T-27]
dbj|BAH39371.1| NADP-dependent isocitrate dehydrogenase [Gemmatimonas aurantiaca
T-27]
Length = 468
Score = 561 bits (1447), Expect = e-158, Method: Composition-based stats.
Identities = 259/407 (63%), Positives = 324/407 (79%), Gaps = 3/407 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKVV+P+VEMDGDE TR+IW+ IK+KLILPYLDV+L YYDL I+ RD T DQVT DS
Sbjct: 64 MAKIKVVNPVVEMDGDEMTRIIWQFIKDKLILPYLDVELDYYDLGIEHRDATGDQVTIDS 123
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ AT K+GVAVKCATITPDEAR+KEF LK+MWKSPNGTIRNILGG +FREPIII IPRL
Sbjct: 124 AEATKKHGVAVKCATITPDEARVKEFGLKKMWKSPNGTIRNILGGVIFREPIIISNIPRL 183
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VPHW KPI++GRHA GDQY+ATD K+ G + + + DG + V +F + GG+AM
Sbjct: 184 VPHWTKPIVVGRHAHGDQYKATDFKVPGPGTVTITYQPADGSAPMQFDVAKFGQDGGVAM 243
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N NDSIK FA+ASF L+R P++ +TKNTILK YD QFK +F+++FD E+K +F+
Sbjct: 244 GMYNYNDSIKDFARASFRYGLQRNFPVYLSTKNTILKAYDGQFKDLFEDVFDAEFKAEFE 303
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
ITYEHRLIDDMVA LK +GG++ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 304 KAGITYEHRLIDDMVASALKWEGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLLTPDG 363
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+G +TSTN IASIFAWTR ++ RGK+D T DV++F LE
Sbjct: 364 KTMEAEAAHGTVTRHYREHQKGNKTSTNPIASIFAWTRGLMHRGKVDGTPDVVRFAETLE 423
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
+ ++ V+ G+MTKDLA+++ K + Y+ TE F+D + +RLQ M
Sbjct: 424 QVCIEAVE-AGEMTKDLAILISKD--TPYLHTENFLDAIDRRLQAKM 467
>ref|XP_367343.2| hypothetical protein MGG_07268 [Magnaporthe grisea 70-15]
gb|EDK04000.1| hypothetical protein MGG_07268 [Magnaporthe grisea 70-15]
Length = 413
Score = 561 bits (1447), Expect = e-158, Method: Composition-based stats.
Identities = 268/406 (66%), Positives = 333/406 (82%), Gaps = 1/406 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TR+IW+ IK+K I PYLD+DLKYYDL ++ RD+T+D+VT D++
Sbjct: 5 AKIKVKNPVVELDGDEMTRIIWQNIKDKFIHPYLDIDLKYYDLGLEYRDKTDDKVTLDAA 64
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KY V VKCATITPDEAR+KEFNLK+MW SPNGTIRN LGGTVFREPI+IP+IPRLV
Sbjct: 65 EAIKKYSVGVKCATITPDEARVKEFNLKQMWLSPNGTIRNALGGTVFREPIVIPRIPRLV 124
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPIIIGRHAFGDQYRA D+ + GKL + F+ G E +++V++F GG+A
Sbjct: 125 PSWQKPIIIGRHAFGDQYRAKDMVVPGEGKLTMTFTPKGG-EPQEIQVFDFKNGGGVAQT 183
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT++SI GFA++SF+LAL + LPL+ +TKN ILK YD +FK IF+ L+ YK +F+A
Sbjct: 184 QYNTDESITGFAQSSFKLALAKGLPLYMSTKNAILKKYDGRFKDIFEQLYQSTYKAEFEA 243
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS GG+I+A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGK
Sbjct: 244 KGIWYEHRLIDDMVAQMIKSTGGYIMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGK 303
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
TFESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+ F LE+
Sbjct: 304 TFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVAFAETLER 363
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
A ++TV + G MTKDLAL GKT RS YVTT E++D V +R+++ +
Sbjct: 364 ACIETVDIDGIMTKDLALACGKTARSDYVTTNEYLDAVERRMKSSL 409
>ref|XP_390523.1| hypothetical protein FG10347.1 [Gibberella zeae PH-1]
Length = 445
Score = 560 bits (1442), Expect = e-157, Method: Composition-based stats.
Identities = 266/405 (65%), Positives = 333/405 (82%), Gaps = 1/405 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +P+VE+DGDE TR+IW++IK+K I PYLD+DLKYYDL ++ RD TNDQVT D++
Sbjct: 38 KIKVKNPVVELDGDEMTRIIWQVIKDKFIHPYLDIDLKYYDLGLEYRDETNDQVTIDAAE 97
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A KY V VKCATITPDEAR++EF LK+MW SPNGTIRN LGGTVFREPI+IP+IPRLVP
Sbjct: 98 AIKKYSVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNALGGTVFREPIVIPRIPRLVP 157
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W+KPIIIGRHAFGDQYRA D + GKL + ++ + G+ +++V++F + GG+A
Sbjct: 158 GWKKPIIIGRHAFGDQYRAKDAVLPGPGKLSMVYTPEGGQPE-EIEVFQFKEGGGVAQTQ 216
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA ASF+LA+ ++LPL+ +TKNTILK YD +FK IF +++ YK++F+A
Sbjct: 217 YNTDESITGFAHASFKLAIDKELPLYMSTKNTILKKYDGRFKDIFQEIYETTYKKEFEAK 276
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQM+KS GG+I+A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGKT
Sbjct: 277 KIWYEHRLIDDMVAQMIKSSGGYIMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGKT 336
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD+T DV+ F LE+A
Sbjct: 337 FESEAAHGTVTRHYREHQKGNETSTNPIASIFAWTRGLIQRGKLDDTPDVVAFAEGLEQA 396
Query: 363 TLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
+DTV + G MTKDLAL GK+ R Y TT E++D V +RL+ +
Sbjct: 397 CIDTVDIDGIMTKDLALATGKSERKDYATTNEYLDAVERRLKKTL 441
>ref|XP_754749.1| isocitrate dehydrogenase Idp1 [Aspergillus fumigatus Af293]
gb|EAL92711.1| isocitrate dehydrogenase Idp1, putative [Aspergillus fumigatus
Af293]
Length = 501
Score = 559 bits (1441), Expect = e-157, Method: Composition-based stats.
Identities = 266/404 (65%), Positives = 331/404 (81%), Gaps = 2/404 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TR+IW+ I+EKLILPYLD+DLKYYDL I+ RD+T+D+VT +++
Sbjct: 94 TKIKVKNPVVELDGDEMTRIIWQEIREKLILPYLDIDLKYYDLGIEYRDQTDDKVTVEAA 153
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRLV
Sbjct: 154 EAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRLV 213
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPIIIGRHAFGDQYRATDI + GKL L ++ ++G E +KVY+F GG+A
Sbjct: 214 PGWNKPIIIGRHAFGDQYRATDIVVPGPGKLELVYTPENG-EPQAIKVYDF-TGGGVAQT 271
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT+DSI+GFA +SF++AL + LPL+ +TKNTILK YD +FK IF +++ YK++F A
Sbjct: 272 QYNTDDSIRGFAHSSFKMALMKGLPLYMSTKNTILKKYDGRFKDIFQEIYESTYKKEFDA 331
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS+GGF++A+KNYDGDVQSD+VAQGFGSLGLMTS L TPDG
Sbjct: 332 KGIWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDVVAQGFGSLGLMTSTLTTPDGS 391
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+ F LE+
Sbjct: 392 AFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVTFAEELER 451
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQN 405
A +D V G MTKDLAL G+ R ++VTT+E++ V +RL++
Sbjct: 452 ACIDVVNEEGIMTKDLALACGRKEREAWVTTKEYLAAVERRLKS 495
>gb|EDP52872.1| isocitrate dehydrogenase Idp1, putative [Aspergillus fumigatus
A1163]
Length = 501
Score = 559 bits (1441), Expect = e-157, Method: Composition-based stats.
Identities = 266/404 (65%), Positives = 331/404 (81%), Gaps = 2/404 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TR+IW+ I+EKLILPYLD+DLKYYDL I+ RD+T+D+VT +++
Sbjct: 94 TKIKVKNPVVELDGDEMTRIIWQEIREKLILPYLDIDLKYYDLGIEYRDQTDDKVTVEAA 153
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRLV
Sbjct: 154 EAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRLV 213
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPIIIGRHAFGDQYRATDI + GKL L ++ ++G E +KVY+F GG+A
Sbjct: 214 PGWNKPIIIGRHAFGDQYRATDIVVPGPGKLELVYTPENG-EPQAIKVYDF-TGGGVAQT 271
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT+DSI+GFA +SF++AL + LPL+ +TKNTILK YD +FK IF +++ YK++F A
Sbjct: 272 QYNTDDSIRGFAHSSFKMALMKGLPLYMSTKNTILKKYDGRFKDIFQEIYESTYKKEFDA 331
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS+GGF++A+KNYDGDVQSD+VAQGFGSLGLMTS L TPDG
Sbjct: 332 KGIWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDVVAQGFGSLGLMTSTLTTPDGS 391
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+ F LE+
Sbjct: 392 AFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVTFAEELER 451
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQN 405
A +D V G MTKDLAL G+ R ++VTT+E++ V +RL++
Sbjct: 452 ACIDVVNEEGIMTKDLALACGRKEREAWVTTKEYLAAVERRLKS 495
>gb|AAK76731.1| peroxisomal NADP-dependent isocitrate dehydrogenase [Aspergillus
nidulans]
Length = 413
Score = 558 bits (1437), Expect = e-157, Method: Composition-based stats.
Identities = 270/404 (66%), Positives = 331/404 (81%), Gaps = 2/404 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KIKV +P+VE+DGDE TR+IWK I+EKLILP+LD+DLKYYDL ++ RD+T+D+VT +S
Sbjct: 5 VQKIKVKNPVVELDGDEMTRIIWKEIREKLILPFLDIDLKYYDLGLEYRDQTDDKVTTES 64
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRL
Sbjct: 65 AEAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRL 124
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPIIIGRHAFGDQYRATD I GKL L ++ + G+ +KV++FP GG+
Sbjct: 125 VPGWTKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPEGGQPEA-IKVFDFP-GGGVTQ 182
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+NT++SI+GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF +F+ +YK++F
Sbjct: 183 TQYNTDESIRGFAHASFKLALTKGLPLYMSTKNTILKKYDGRFKDIFQEIFESDYKKEFD 242
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQM+KS+GGFI+A+KNYDGDVQSDIVAQGFGSLGLMTS LITPDG
Sbjct: 243 AKGIWYEHRLIDDMVAQMIKSEGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSTLITPDG 302
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+ FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+KF LE
Sbjct: 303 QAFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVKFAEELE 362
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
+A +D V G MTKDLAL G+ R ++VTT E++ V +RL+
Sbjct: 363 RACIDVVNEEGIMTKDLALSCGRKERDAWVTTREYMAAVERRLR 406
>sp|P79089|IDHP_ASPNG Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP)
dbj|BAA19073.1| NADP-dependent isocitrate dehydrogenase precursor [Aspergillus
niger]
dbj|BAA19074.1| NADP-dependent isocitrate dehydrogenase precursor [Aspergillus
niger]
Length = 498
Score = 553 bits (1426), Expect = e-156, Method: Composition-based stats.
Identities = 265/404 (65%), Positives = 328/404 (81%), Gaps = 2/404 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KIKV +P+VE+DGDE TR+IW+ I+EKLILPYLDVDLKYYDL ++ RD+T+DQVT ++
Sbjct: 90 IPKIKVKNPVVELDGDEMTRIIWQEIREKLILPYLDVDLKYYDLGLEYRDQTDDQVTVEA 149
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPIIIP IPRL
Sbjct: 150 AEAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIIIPAIPRL 209
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPIIIGRHAFGDQYRATD I GKL L ++ +G+ +KVY+F + GGIA
Sbjct: 210 VPGWNKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPVNGEPET-VKVYDF-QGGGIAQ 267
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+NT++SI+GFA ASF++AL + LPL+ +TKNTILK YD +FK IF +++ Y++ F+
Sbjct: 268 TQYNTDESIRGFAHASFQMALLKGLPLYMSTKNTILKRYDGRFKDIFQEIYESTYQKDFE 327
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A + YEHRLIDDMVAQM+KS+GGF++A+KNYDGDVQSDIVAQGFGSLGLMTS L+TP G
Sbjct: 328 AKNLWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSTLVTPTG 387
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+ FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+ F LE
Sbjct: 388 EAFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVTFAEELE 447
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
+A ++ V G MTKDLAL G+ R ++VTT E++ V +RL+
Sbjct: 448 RACIEVVNDEGIMTKDLALACGRKEREAWVTTREYMAAVERRLK 491
>gb|EDU40785.1| isocitrate dehydrogenase, mitochondrial precursor [Pyrenophora
tritici-repentis Pt-1C-BFP]
Length = 416
Score = 553 bits (1424), Expect = e-155, Method: Composition-based stats.
Identities = 266/407 (65%), Positives = 330/407 (81%), Gaps = 1/407 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+SKIKV +P+VE+DGDE TR+IW++IK+K I PYLD+DLKYYDL + RD TNDQVT D+
Sbjct: 7 ISKIKVKNPVVELDGDEMTRIIWQVIKDKFIHPYLDIDLKYYDLGLPYRDETNDQVTLDA 66
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MW SPNGTIRN LGGTVFR PI+IP IPRL
Sbjct: 67 AEAIKKYSVGVKCATITPDEQRVEEFKLKKMWLSPNGTIRNHLGGTVFRAPIVIPTIPRL 126
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W++PIIIGRHAFGDQYRA D I G L + F+ GK + +KVY+FP GG+A
Sbjct: 127 VPGWKQPIIIGRHAFGDQYRAKDRVISGEGTLEMVFTPKGGKPEV-IKVYDFPAEGGVAQ 185
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+NT +SI GFA ASF++AL +KLPL+ +TKNTILK YD +FK +F +++ +YK+ F+
Sbjct: 186 TQYNTTESITGFAHASFKMALDKKLPLYMSTKNTILKAYDGKFKDVFQAIYESQYKKDFE 245
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQM+KS+GG+IIAMKNYDGDVQSDIVAQGFGSLGLMTS LITPDG
Sbjct: 246 AAKIWYEHRLIDDMVAQMIKSEGGYIIAMKNYDGDVQSDIVAQGFGSLGLMTSTLITPDG 305
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFE+EAAHGTVTRHFR+HQ+G ETSTN IASI+AWT+ + +RG+LDNT +++ F LE
Sbjct: 306 KTFEAEAAHGTVTRHFREHQKGNETSTNPIASIYAWTQGLAKRGELDNTPELVVFAEQLE 365
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
KA +DTV + MTKDLAL GK +R+S+VTT E++D V +RL++ +
Sbjct: 366 KACVDTVDIDKIMTKDLALACGKKDRASWVTTNEYLDAVERRLKSSL 412
>ref|XP_001240510.1| isocitrate dehydrogenase NADP, mitochondrial precursor
[Coccidioides immitis RS]
gb|EAS28927.1| isocitrate dehydrogenase NADP, mitochondrial precursor
[Coccidioides immitis RS]
Length = 509
Score = 551 bits (1421), Expect = e-155, Method: Composition-based stats.
Identities = 265/408 (64%), Positives = 328/408 (80%), Gaps = 2/408 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +P+VE+DGDE TR+IW+ IK+K I PYLDVDLKYYDL ++ RD+T+D+VT D++
Sbjct: 102 KIKVKNPVVELDGDEMTRIIWQDIKDKFIYPYLDVDLKYYDLGLEYRDQTDDKVTVDAAE 161
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRLVP
Sbjct: 162 AIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRLVP 221
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W+KPIIIGRHAFGDQYRATD + GKL L ++ +G E + VY+F + GIA
Sbjct: 222 GWKKPIIIGRHAFGDQYRATDRLVPGPGKLELVYTPTNG-EPERITVYDF-QGAGIAQVQ 279
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT+DSI+GFA ASF+LAL + LP++ +TKNTILK YD +FK IF+ +++ EYK+ F+A
Sbjct: 280 YNTDDSIRGFAHASFKLALLKGLPMYMSTKNTILKKYDGRFKDIFEEVYEAEYKKAFEAK 339
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVAQM+K GG +IAMKNYDGDVQSDIVAQGFGSLGLMTS L TPDG
Sbjct: 340 GIWYEHRLIDDMVAQMIKGDGGCVIAMKNYDGDVQSDIVAQGFGSLGLMTSTLTTPDGSA 399
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +I+RG+LD T DV+ F LE+A
Sbjct: 400 FESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIRRGQLDETPDVVTFAEQLERA 459
Query: 363 TLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSS 410
++ V G MTKDLAL GK R ++VTT E++D V +RL++ + ++
Sbjct: 460 CIEVVDEEGIMTKDLALSCGKKERDAWVTTREYMDAVERRLRSNLANA 507
>ref|ZP_01862723.1| isocitrate dehydrogenase [Erythrobacter sp. SD-21]
gb|EDL50158.1| isocitrate dehydrogenase [Erythrobacter sp. SD-21]
Length = 406
Score = 550 bits (1417), Expect = e-155, Method: Composition-based stats.
Identities = 264/407 (64%), Positives = 332/407 (81%), Gaps = 5/407 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE T++IWK I+E+LILPYLDVDLKYYDLSI++RD T+DQ+T D+
Sbjct: 1 MAKIKVANPVVELDGDEMTKIIWKWIRERLILPYLDVDLKYYDLSIEKRDETDDQITVDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A ++GV VKCATITPDEAR++EF+LK+MW+SPNGTIRNILGG VFREPI+I +PRL
Sbjct: 61 ANAIKEHGVGVKCATITPDEARVEEFDLKKMWRSPNGTIRNILGGVVFREPIVIDNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W PI++GRHAFGDQYRATD I AGKLRL F ++G ENIDL V+EF +S G+AM
Sbjct: 121 VPGWTDPIVVGRHAFGDQYRATDTLIPGAGKLRLVFEGENG-ENIDLDVFEF-QSPGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N +DSI+ FA+ASF+ L RK P++ +TKNTILK YD +FK +F +FD EYK++F+
Sbjct: 179 AMYNLDDSIRDFARASFQYGLDRKWPVYLSTKNTILKKYDGRFKDLFQEIFDAEYKDQFE 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
ITYEHRLIDDMVA LK G F+ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 239 KHGITYEHRLIDDMVAAALKWNGKFVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+G+ TSTN IASIFAWTR ++ RGK DNT +V+KF LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQQGKATSTNPIASIFAWTRGLMYRGKFDNTPEVVKFAETLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
+ + TV+ GKMTKDLAL++G S++TTE+F + + + L+ M
Sbjct: 359 QVCIKTVE-SGKMTKDLALLIGPDQ--SWMTTEQFFEAIVEGLEAEM 402
>ref|XP_660603.1| IDHP_ASPNG ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR
(OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC
ICDH) (IDP) [Aspergillus nidulans FGSC A4]
gb|EAA63570.1| IDHP_ASPNG ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR
(OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC
ICDH) (IDP) [Aspergillus nidulans FGSC A4]
Length = 491
Score = 549 bits (1414), Expect = e-154, Method: Composition-based stats.
Identities = 266/404 (65%), Positives = 327/404 (80%), Gaps = 4/404 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+ KIKV +P+VE+DGDE TR+IWK I+EK +LD+DLKYYDL ++ RD+T+D+VT +S
Sbjct: 85 VQKIKVKNPVVELDGDEMTRIIWKEIREKA--SFLDIDLKYYDLGLEYRDQTDDKVTTES 142
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRL
Sbjct: 143 AEAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRL 202
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPIIIGRHAFGDQYRATD I GKL L ++ + G+ +KV++FP GG+
Sbjct: 203 VPGWTKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPEGGQPEA-IKVFDFP-GGGVTQ 260
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+NT++SI+GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF +F+ +YK++F
Sbjct: 261 TQYNTDESIRGFAHASFKLALTKGLPLYMSTKNTILKKYDGRFKDIFQEIFESDYKKEFD 320
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQM+KS+GGFI+A+KNYDGDVQSDIVAQGFGSLGLMTS LITPDG
Sbjct: 321 AKGIWYEHRLIDDMVAQMIKSEGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSTLITPDG 380
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+ FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+KF LE
Sbjct: 381 QAFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVKFAEELE 440
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
+A +D V G MTKDLAL G+ R ++VTT E++ V +RL+
Sbjct: 441 RACIDVVNEEGIMTKDLALSCGRKERDAWVTTREYMAAVERRLR 484
>ref|XP_001400371.1| precursor of mitochondrial isocitrate dehydrogenase
icdA-Aspergillus niger
emb|CAK44510.1| precursor of mitochondrial isocitrate dehydrogenase
icdA-Aspergillus niger
Length = 413
Score = 547 bits (1409), Expect = e-154, Method: Composition-based stats.
Identities = 262/404 (64%), Positives = 328/404 (81%), Gaps = 2/404 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
+SKIKV +P+VE+DGDE TR+IW+ I+EKLILP+LDVDLKYYDL ++ RD+T+DQVT ++
Sbjct: 5 ISKIKVKNPVVELDGDEMTRIIWQEIREKLILPFLDVDLKYYDLGLEYRDQTDDQVTVEA 64
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPIII IPRL
Sbjct: 65 AEAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIIIXTIPRL 124
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPIIIGRHAFGDQYRATD I GKL L ++ +G+ ++VY+F + GG+A
Sbjct: 125 VPGWNKPIIIGRHAFGDQYRATDRVIPGPGKLELVYTPANGEPET-VQVYDF-QGGGVAQ 182
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+NT++SI+GFA ASF++AL + LPL+ +TKNTILK YD +FK IF +++ Y++ F+
Sbjct: 183 TQYNTDESIRGFAHASFQMALLKGLPLYMSTKNTILKRYDGRFKDIFQEIYESTYQKDFE 242
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A + YEHRLIDDMVAQM+KS+GGF++A+KNYDGDVQSDIVAQGFGSLGLMTS L+TP G
Sbjct: 243 AKNLWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDIVAQGFGSLGLMTSTLVTPTG 302
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+ FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR ++QRGKLD T DV+ F LE
Sbjct: 303 EAFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLVQRGKLDETPDVVTFAEELE 362
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
+A +D V G MTKDLAL G+ R ++VTT E++ V +RL+
Sbjct: 363 RACIDVVNEEGIMTKDLALACGRKEREAWVTTREYLAAVERRLK 406
>ref|XP_001263574.1| isocitrate dehydrogenase Idp1, putative [Neosartorya fischeri NRRL
181]
gb|EAW21677.1| isocitrate dehydrogenase Idp1, putative [Neosartorya fischeri NRRL
181]
Length = 413
Score = 545 bits (1403), Expect = e-153, Method: Composition-based stats.
Identities = 260/404 (64%), Positives = 328/404 (81%), Gaps = 2/404 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TR+IW+ I+EK+ YLD+DLKYYDL I+ RD+T+D+VT +++
Sbjct: 6 TKIKVKNPVVELDGDEMTRIIWQEIREKVSPSYLDIDLKYYDLGIEYRDQTDDKVTVEAA 65
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRLV
Sbjct: 66 EAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRLV 125
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPIIIGRHAFGDQYRATDI + GKL L ++ ++G+ +KVY+F GG+A
Sbjct: 126 PGWNKPIIIGRHAFGDQYRATDIVVPGPGKLELVYTPENGEPQA-IKVYDF-TGGGVAQT 183
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT+DSI+GFA +SF++AL + LPL+ +TKNTILK YD +FK IF +++ YK++F A
Sbjct: 184 QYNTDDSIRGFAHSSFKMALMKGLPLYMSTKNTILKKYDGRFKDIFQEIYESTYKKEFDA 243
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS+GGF++A+KNYDGDVQSD+VAQGFGSLGLMTS L TPDG
Sbjct: 244 KGIWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDVVAQGFGSLGLMTSTLTTPDGS 303
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR ++QRGKLD T DV+ F LE+
Sbjct: 304 AFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLVQRGKLDETPDVVAFAEELER 363
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQN 405
A +D V G MTKDLAL G+ R ++VTT+E++ V +RL++
Sbjct: 364 ACIDVVNEEGIMTKDLALACGRKEREAWVTTKEYLAAVERRLKS 407
>ref|YP_496560.1| isocitrate dehydrogenase [Novosphingobium aromaticivorans DSM
12444]
gb|ABD25726.1| isocitrate dehydrogenase (NADP) [Novosphingobium aromaticivorans
DSM 12444]
Length = 407
Score = 543 bits (1400), Expect = e-153, Method: Composition-based stats.
Identities = 261/408 (63%), Positives = 325/408 (79%), Gaps = 6/408 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW+ I+E+LILPYLD+DLKYYDLS+Q+RD TNDQ+T DS
Sbjct: 1 MAKIKVKNPVVEIDGDEMTRIIWEWIRERLILPYLDIDLKYYDLSVQKRDETNDQITIDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDEAR++EFNLK MWKSPNGTIRNILGG VFREPI+I +PRL
Sbjct: 61 ANAIKQYGVGVKCATITPDEARVEEFNLKSMWKSPNGTIRNILGGVVFREPIVIQNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W PI++GRHAFGDQYRATD + GKLRL + D+G E ID +V+ +P SGG+AM
Sbjct: 121 VPGWTDPIVVGRHAFGDQYRATDFVVPGPGKLRLVWEGDNG-ETIDREVFNYP-SGGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKE-YKEKF 239
AM+N +DSI+ FA+ASF L P++ +TKNTILK YD +FK +F +FD E +KEKF
Sbjct: 179 AMYNLDDSIRDFARASFNYGLGLGWPVYLSTKNTILKAYDGRFKDLFQEVFDTEGFKEKF 238
Query: 240 QALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPD 299
A I YEHRLIDDMVA LK G F+ A KNYDGDVQSD VAQGFGSLGLMTS+L+TPD
Sbjct: 239 AAAGIVYEHRLIDDMVASALKWSGKFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPD 298
Query: 300 GKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLL 359
GKT E+EAAHGTVTRH+R+HQ+G++TSTN IASIFAWTR +I RGK D T +V+KF L
Sbjct: 299 GKTVEAEAAHGTVTRHYRQHQQGKQTSTNPIASIFAWTRGLIYRGKFDETPEVVKFAETL 358
Query: 360 EKATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
E+ ++TV+ GKMTKDLAL++G +++TTE+F + + + L+ M
Sbjct: 359 ERVCIETVE-SGKMTKDLALLIGPDQ--AWMTTEKFFEAIVENLETEM 403
>ref|ZP_01040029.1| isocitrate dehydrogenase [Erythrobacter sp. NAP1]
gb|EAQ30500.1| isocitrate dehydrogenase [Erythrobacter sp. NAP1]
Length = 406
Score = 540 bits (1390), Expect = e-151, Method: Composition-based stats.
Identities = 256/409 (62%), Positives = 328/409 (80%), Gaps = 5/409 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M KI+V +PIVE+DGDE T++IW+ I+E+LILPYLDVDLKYYDLS+++RD T+DQ+T D+
Sbjct: 1 MQKIQVKNPIVELDGDEMTKIIWQWIRERLILPYLDVDLKYYDLSVEKRDETDDQITIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDEAR++EF+LK+MWKSPNGTIRNILGG VFREPI+I +PRL
Sbjct: 61 ANAIKEYGVGVKCATITPDEARVEEFDLKKMWKSPNGTIRNILGGVVFREPIVIDNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W PI++GRHAFGDQYRATD I GKLR+ + DDG E IDL V++FP S GIAM
Sbjct: 121 VPGWTHPIVVGRHAFGDQYRATDTLIPGPGKLRMVYHGDDGTE-IDLNVFDFP-SAGIAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
+M+N +DSI+ FA+AS L RK P++ +TKNTI+K YD +FK +F +FD E+ +KF+
Sbjct: 179 SMYNLDDSIRDFARASMNYGLDRKWPVYLSTKNTIMKAYDGRFKDLFQEVFDAEFADKFK 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
ITYEHRLIDDMVA LK G F+ A KNYDGDVQSD VAQGFGSLGLMTS+L+TPDG
Sbjct: 239 EAGITYEHRLIDDMVASALKWSGKFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+G+ TSTN IASIFAWTR ++ RGK D+T DV++F LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQQGKATSTNPIASIFAWTRGLMYRGKFDDTPDVVRFAETLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
+ ++TV+ G+MTKDLAL++G + +++TTE+F + + + L+ M S
Sbjct: 359 RVCIETVE-NGQMTKDLALLIGPSQ--NWLTTEQFFEAIVQNLEKEMQS 404
>ref|YP_001413846.1| isocitrate dehydrogenase, NADP-dependent [Parvibaculum
lavamentivorans DS-1]
gb|ABS64189.1| isocitrate dehydrogenase, NADP-dependent [Parvibaculum
lavamentivorans DS-1]
Length = 407
Score = 539 bits (1389), Expect = e-151, Method: Composition-based stats.
Identities = 257/407 (63%), Positives = 324/407 (79%), Gaps = 4/407 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M KIKV +P+V++DGDE TR+IW++IK+KLI PYLD+D+ YYDL ++ RD T+D+VT +S
Sbjct: 1 MPKIKVANPVVDLDGDEMTRIIWQMIKDKLIFPYLDLDIDYYDLGMEHRDATDDKVTVES 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRL
Sbjct: 61 AEAIKKYGVGVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICRNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W +PI+IGRHAFGDQYRATDI I GKL +++ S+DGK+ I+ ++++FP S G+AM
Sbjct: 121 VPGWTEPIVIGRHAFGDQYRATDILIPGKGKLTMKWVSEDGKDTIEEEIFDFP-SAGVAM 179
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N +DSI+ FA+A + L RK P++ +TKNTILK YD +FK +F +++KE+K F+
Sbjct: 180 GMYNLDDSIRDFARACMKFGLARKYPVYLSTKNTILKTYDGRFKNLFQEIYEKEFKADFE 239
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KITYEHRLIDDMVA +K GG++ A KNYDGDVQSD VAQGFGSLGLMTS+L+TPDG
Sbjct: 240 AAKITYEHRLIDDMVASAMKWSGGYVWACKNYDGDVQSDSVAQGFGSLGLMTSVLLTPDG 299
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
K E+EAAHGTVTRHFR HQRGEETSTNSIASIFAWTR + R KLD D++ KF LE
Sbjct: 300 KIMEAEAAHGTVTRHFRAHQRGEETSTNSIASIFAWTRGLTHRAKLDGNDELAKFAQTLE 359
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
K + TV+ G MTKDLAL++G + S+++TE F+D+VA L +
Sbjct: 360 KVCVSTVE-SGHMTKDLALLVG--SEQSWLSTEGFLDKVAANLDKAL 403
>gb|EEJ98364.1| isocitrate dehydrogenase (NADP) [Thermomonospora curvata DSM 43183]
Length = 407
Score = 539 bits (1388), Expect = e-151, Method: Composition-based stats.
Identities = 254/404 (62%), Positives = 316/404 (78%), Gaps = 3/404 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M KIKV P+VE+DGDE TR+IWK IK++LILPYLD+DLKYYDL IQ RD T+DQVT D+
Sbjct: 1 MPKIKVAGPVVELDGDEMTRIIWKFIKDQLILPYLDIDLKYYDLGIQNRDATDDQVTVDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR++EF LK+MW+SPNGTIRNILGG VFREPII+ IPRL
Sbjct: 61 ANAIKKYGVGVKCATITPDEARVEEFGLKQMWRSPNGTIRNILGGVVFREPIIVSNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPI+IGRHA GDQY+ATD K+ G L + ++ DDG E I +V +P+ GG+AM
Sbjct: 121 VPGWTKPIVIGRHAHGDQYKATDFKVPGPGTLTITYTPDDGSEPIQFEVARYPEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N SI+ FA+ASF L R P++ +TKNTILK YD FK +F +++ E+KE+F+
Sbjct: 181 GMYNFRKSIEDFARASFRYGLDRNYPVYLSTKNTILKAYDGMFKDVFAEIYENEFKEEFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A +TYEHRLIDDMVA LK +GG++ A KNYDGDVQSD VAQGFGSLGLMTS+L+TPDG
Sbjct: 241 ARGLTYEHRLIDDMVACALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+T E+EAAHGTVTRH+R HQ+G+ TSTN IASIFAWTR + RGKLDNT +VIKF LE
Sbjct: 301 RTVEAEAAHGTVTRHYRLHQQGKPTSTNPIASIFAWTRGLAHRGKLDNTPEVIKFAETLE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQ 404
+ ++TV+ G+MTKDLAL++ K ++TT+EF+ + LQ
Sbjct: 361 QVCIETVE-SGQMTKDLALLISKDQ--PWLTTQEFLHALDVNLQ 401
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
emb|CAM77136.1| Isocitrate/isopropylmalate dehydrogenase [M... 704 0.0
ref|NP_539708.1| isocitrate dehydrogenase [Brucella meliten... 704 0.0
ref|NP_698203.1| isocitrate dehydrogenase [Brucella suis 13... 703 0.0
ref|XP_001903959.1| unnamed protein product [Podospora anse... 701 0.0
ref|XP_536192.2| PREDICTED: similar to isocitrate dehydroge... 699 0.0
ref|XP_001226620.1| conserved hypothetical protein [Chaetom... 699 0.0
ref|XP_955850.1| hypothetical protein NCU03857 [Neurospora ... 699 0.0
gb|EEJ98364.1| isocitrate dehydrogenase (NADP) [Thermomonos... 699 0.0
ref|NP_786984.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 698 0.0
sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitoc... 698 0.0
gb|ACO14046.1| Isocitrate dehydrogenase, mitochondrial prec... 698 0.0
ref|NP_001026770.1| hypothetical protein LOC431056 [Gallus ... 698 0.0
ref|NP_970434.1| isocitrate dehydrogenase [Bdellovibrio bac... 698 0.0
ref|XP_421965.2| PREDICTED: similar to cytosolic NADP-depen... 698 0.0
gb|ABU41004.1| isocitrate dehydrogenase 1 [Anser anser] 698 0.0
ref|NP_955858.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 697 0.0
sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytopl... 697 0.0
sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitoc... 696 0.0
gb|ABE98244.1| mitochondrial isocitrate dehydrogenase 2-lik... 696 0.0
sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytopl... 696 0.0
ref|XP_001107627.1| PREDICTED: isocitrate dehydrogenase 1 (... 696 0.0
ref|XP_754749.1| isocitrate dehydrogenase Idp1 [Aspergillus... 696 0.0
gb|EDP52872.1| isocitrate dehydrogenase Idp1, putative [Asp... 696 0.0
ref|YP_002826161.1| NADP isocitrate dehydrogenase [Rhizobiu... 696 0.0
ref|XP_001778805.1| predicted protein [Physcomitrella paten... 696 0.0
gb|EDN62799.1| NADP-dependent isocitrate dehydrogenase [Sac... 696 0.0
ref|NP_014389.1| Peroxisomal NADP-dependent isocitrate dehy... 695 0.0
ref|XP_001369305.1| PREDICTED: hypothetical protein [Monode... 695 0.0
ref|NP_766599.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 695 0.0
ref|NP_001009276.1| cytosolic NADP-isocitrate dehydrogenase... 695 0.0
ref|NP_851355.2| isocitrate dehydrogenase 1 (NADP+), solubl... 695 0.0
ref|NP_001088022.1| hypothetical protein LOC494713 [Xenopus... 695 0.0
ref|YP_001370537.1| isocitrate dehydrogenase, NADP-dependen... 695 0.0
ref|NP_113698.1| isocitrate dehydrogenase 1 (NADP+), solubl... 695 0.0
ref|YP_419971.1| isocitrate dehydrogenase [Magnetospirillum... 694 0.0
ref|XP_001240510.1| isocitrate dehydrogenase NADP, mitochon... 694 0.0
ref|ZP_02188085.1| Isocitrate dehydrogenase [alpha proteoba... 694 0.0
ref|NP_001014183.1| isocitrate dehydrogenase 2 (NADP+), mit... 694 0.0
emb|CAG38738.1| IDH1 [Homo sapiens] 694 0.0
ref|ZP_00056387.1| COG0538: Isocitrate dehydrogenases [Magn... 693 0.0
ref|NP_005887.2| isocitrate dehydrogenase 1 (NADP+), solubl... 693 0.0
ref|XP_510589.2| PREDICTED: isocitrate dehydrogenase 2 (NAD... 693 0.0
sp|Q5R9C5|IDHC_PONPY Isocitrate dehydrogenase [NADP] cytopl... 693 0.0
sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytopl... 693 0.0
ref|YP_290624.1| isocitrate dehydrogenase [Thermobifida fus... 693 0.0
ref|XP_850187.1| PREDICTED: similar to Isocitrate dehydroge... 692 0.0
dbj|BAC39792.1| unnamed protein product [Mus musculus] 692 0.0
ref|XP_001141655.1| PREDICTED: isocitrate dehydrogenase 1 (... 692 0.0
ref|XP_001095686.1| PREDICTED: isocitrate dehydrogenase 2 (... 692 0.0
gb|AAC64182.1| NADP-dependent isocitrate dehydrogenase [Gly... 692 0.0
ref|NP_002159.2| isocitrate dehydrogenase 2 (NADP+), mitoch... 692 0.0
pdb|1LWD|A Chain A, Crystal Structure Of Nadp-Dependent Iso... 691 0.0
gb|AAH93020.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 691 0.0
ref|NP_385898.1| isocitrate dehydrogenase [Sinorhizobium me... 691 0.0
sp|P33198|IDHP_PIG Isocitrate dehydrogenase [NADP], mitocho... 691 0.0
emb|CAA53300.1| isocitrate dehydrogenase (NADP+) [Solanum t... 691 0.0
emb|CAA49208.1| isocitrate dehydrogenase (NADP+) [Homo sapi... 691 0.0
ref|XP_451683.1| unnamed protein product [Kluyveromyces lac... 691 0.0
emb|CAH89719.1| hypothetical protein [Pongo abelii] 691 0.0
sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytopl... 690 0.0
emb|CAB66637.1| hypothetical protein [Homo sapiens] >gi|117... 690 0.0
emb|CAD97653.1| hypothetical protein [Homo sapiens] >gi|117... 690 0.0
gb|AAB39248.1| NADP-isocitrate dehydrogenase [Eucalyptus gl... 690 0.0
ref|NP_001080321.1| hypothetical protein LOC380013 [Xenopus... 690 0.0
dbj|BAD96636.1| isocitrate dehydrogenase 2 (NADP+), mitocho... 690 0.0
gb|AAD02918.1| NADP-dependent isocitrate dehydrogenase [Hom... 689 0.0
ref|NP_034627.3| isocitrate dehydrogenase 1 (NADP+), solubl... 689 0.0
ref|YP_425448.1| isocitrate dehydrogenase [Rhodospirillum r... 689 0.0
gb|AAF73472.1|AF268076_1 NADP-dependent isocitrate dehydrog... 689 0.0
ref|XP_001593497.1| hypothetical protein SS1G_04924 [Sclero... 689 0.0
ref|XP_001505172.1| PREDICTED: similar to Isocitrate dehydr... 689 0.0
dbj|BAC77065.1| NADP-specific isocitrate dehydrogenase [Lup... 689 0.0
emb|CAH91635.1| hypothetical protein [Pongo abelii] 689 0.0
ref|YP_001327198.1| isocitrate dehydrogenase [Sinorhizobium... 689 0.0
sp|Q40345|IDHP_MEDSA Isocitrate dehydrogenase [NADP], chlor... 689 0.0
dbj|BAE39644.1| unnamed protein product [Mus musculus] 689 0.0
gb|AAH88986.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 689 0.0
emb|CAG13105.1| unnamed protein product [Tetraodon nigrovir... 688 0.0
ref|YP_002761841.1| NADP-dependent isocitrate dehydrogenase... 688 0.0
ref|ZP_02166681.1| isocitrate dehydrogenase [Hoeflea photot... 688 0.0
gb|EDT29808.1| isocitrate dehydrogenase, NADP-dependent [Ol... 688 0.0
gb|EAX02083.1| isocitrate dehydrogenase 2 (NADP+), mitochon... 688 0.0
ref|ZP_03891012.1| isocitrate dehydrogenase (NADP) [Geoderm... 688 0.0
ref|YP_706173.1| isocitrate dehydrogenase [Rhodococcus sp. ... 688 0.0
ref|ZP_02124492.1| Isocitrate dehydrogenase (NADP(+)) [Meth... 688 0.0
ref|XP_001168316.1| PREDICTED: isocitrate dehydrogenase 2 (... 688 0.0
ref|YP_673828.1| isocitrate dehydrogenase [Mesorhizobium sp... 688 0.0
pdb|2CMJ|A Chain A, Crystal Structure Of Mouse Cytosolic Is... 687 0.0
ref|YP_872148.1| isocitrate dehydrogenase [Acidothermus cel... 687 0.0
emb|CAG38553.1| IDH1 [Homo sapiens] 687 0.0
gb|AAT06312.1| isocitrate dehydrogenase [Rhizobium legumino... 687 0.0
ref|ZP_02295934.1| isocitrate dehydrogenase, NADP-dependent... 687 0.0
ref|XP_001511049.1| PREDICTED: similar to cytosolic NADP-de... 687 0.0
ref|ZP_01885694.1| isocitrate dehydrogenase [Pedobacter sp.... 687 0.0
sp|P50218|IDHC_TOBAC Isocitrate dehydrogenase [NADP] (Oxalo... 687 0.0
ref|YP_768215.1| isocitrate dehydrogenase [Rhizobium legumi... 687 0.0
ref|XP_504978.1| hypothetical protein [Yarrowia lipolytica]... 686 0.0
ref|ZP_03869030.1| isocitrate dehydrogenase (NADP) [Jonesia... 686 0.0
ref|NP_101923.1| isocitrate dehydrogenase [Mesorhizobium lo... 686 0.0
ref|NP_001004799.1| MGC69505 protein [Xenopus tropicalis] >... 686 0.0
gb|AAK76730.1| mitochondrial NADP-dependent isocitrate dehy... 686 0.0
ref|NP_421325.1| isocitrate dehydrogenase [Caulobacter cres... 686 0.0
ref|YP_001413846.1| isocitrate dehydrogenase, NADP-dependen... 686 0.0
ref|NP_001056381.1| Os05g0573200 [Oryza sativa (japonica cu... 686 0.0
ref|ZP_02858718.1| isocitrate dehydrogenase, NADP-dependent... 686 0.0
emb|CAG02362.1| unnamed protein product [Tetraodon nigrovir... 685 0.0
ref|XP_390523.1| hypothetical protein FG10347.1 [Gibberella... 685 0.0
gb|AAA33978.1| NADPH-specific isocitrate dehydrogenase 685 0.0
dbj|BAA34113.1| NADP specific isocitrate dehydrogenase [Dau... 685 0.0
gb|ABA18651.1| cytosolic NADP+-isocitrate dehydrogenase [Po... 685 0.0
sp|P50217|IDHC_SOLTU Isocitrate dehydrogenase [NADP] (Oxalo... 685 0.0
ref|XP_001633903.1| predicted protein [Nematostella vectens... 685 0.0
gb|ABK24873.1| unknown [Picea sitchensis] 685 0.0
ref|NP_001043749.1| Os01g0654500 [Oryza sativa (japonica cu... 684 0.0
dbj|BAA34112.1| NADP specific isocitrate dehydrogenase [Dau... 684 0.0
ref|XP_001365492.1| PREDICTED: similar to cytosolic NADP-de... 684 0.0
ref|XP_001168291.1| PREDICTED: isocitrate dehydrogenase 2 (... 684 0.0
pir||S33612 isocitrate dehydrogenase (NADP) (EC 1.1.1.42) -... 684 0.0
ref|YP_001524781.1| NADP-dependent isocitrate dehydrogenase... 684 0.0
dbj|BAE48792.1| NADP-isocitrate dehydrogenase [Codonopsis l... 684 0.0
ref|XP_001384028.1| Isocitrate dehydrogenase [NADP], mitoch... 684 0.0
sp|P79089|IDHP_ASPNG Isocitrate dehydrogenase [NADP], mitoc... 684 0.0
ref|NP_354851.2| isocitrate dehydrogenase [Agrobacterium tu... 683 0.0
ref|XP_367343.2| hypothetical protein MGG_07268 [Magnaporth... 683 0.0
gb|AAL11503.1|AF367443_1 NADP-dependent isocitrate dehydrog... 683 0.0
ref|XP_001528456.1| isocitrate dehydrogenase, mitochondrial... 683 0.0
ref|YP_117132.1| isocitrate dehydrogenase [Nocardia farcini... 683 0.0
dbj|BAC77063.1| NADP-specific isocitrate dehydrogenase [Lup... 683 0.0
emb|CAA73139.1| isocitrate dehydrogenase (NADP+) [Apium gra... 683 0.0
gb|AAD51361.1|AF176669_1 NADP-isocitrate dehydrogenase [Cit... 682 0.0
ref|YP_001609735.1| NADP-dependent isocitrate dehydrogenase... 682 0.0
ref|YP_001769504.1| isocitrate dehydrogenase, NADP-dependen... 682 0.0
ref|XP_001778590.1| predicted protein [Physcomitrella paten... 682 0.0
emb|CAD24779.1| isocitrate dehydrogenase [Cucumis sativus] 681 0.0
ref|YP_001685152.1| isocitrate dehydrogenase, NADP-dependen... 681 0.0
dbj|BAC77064.1| NADP-specific isocitrate dehydrogenase [Lup... 681 0.0
ref|XP_710919.1| NADP-specific isocitrate dehydrogenase [Ca... 681 0.0
gb|AAC52473.1| isocitrate dehydrogenase 681 0.0
ref|YP_677841.1| isocitrate dehydrogenase [Cytophaga hutchi... 681 0.0
ref|YP_002783489.1| isocitrate dehydrogenase [Rhodococcus o... 681 0.0
prf||2211361A isocitrate dehydrogenase 681 0.0
ref|XP_860821.1| PREDICTED: similar to Isocitrate dehydroge... 681 0.0
ref|YP_002765452.1| NADP-dependent isocitrate dehydrogenase... 680 0.0
ref|ZP_01040029.1| isocitrate dehydrogenase [Erythrobacter ... 680 0.0
gb|AAV33246.1| isocitrate dehydrogenase [Toxoplasma gondii] 680 0.0
ref|ZP_01303522.1| isocitrate dehydrogenase, NADP-dependent... 680 0.0
ref|ZP_00952302.1| isocitrate dehydrogenase [Oceanicaulis a... 680 0.0
ref|XP_001688948.1| AGAP006660-PA [Anopheles gambiae str. P... 680 0.0
emb|CAQ15240.1| isocitrate dehydrogenase 1 (NADP+), soluble... 680 0.0
ref|NP_958907.1| isocitrate dehydrogenase 1 (NADP+), solubl... 680 0.0
ref|ZP_01862723.1| isocitrate dehydrogenase [Erythrobacter ... 680 0.0
sp|Q06197|IDHC_SOYBN Isocitrate dehydrogenase [NADP] (Oxalo... 679 0.0
ref|XP_001263574.1| isocitrate dehydrogenase Idp1, putative... 679 0.0
emb|CAA65503.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 679 0.0
ref|YP_496560.1| isocitrate dehydrogenase [Novosphingobium ... 679 0.0
ref|ZP_01228834.1| NADP dependent isocitrate dehydrogenase ... 679 0.0
ref|XP_001841910.1| isocitrate dehydrogenase cytoplasmic [C... 679 0.0
ref|XP_001168261.1| PREDICTED: isocitrate dehydrogenase 2 (... 678 0.0
ref|YP_001623415.1| isocitrate dehydrogenase (NADP) [Reniba... 678 0.0
emb|CAA65504.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 678 0.0
gb|AAS49171.1| NADP-dependent isocitrate dehydrogenase [Pis... 678 0.0
ref|ZP_01546031.1| isocitrate dehydrogenase [Stappia aggreg... 678 0.0
ref|NP_772387.1| isocitrate dehydrogenase [Bradyrhizobium j... 678 0.0
ref|XP_860853.1| PREDICTED: similar to Isocitrate dehydroge... 678 0.0
ref|YP_001538953.1| isocitrate dehydrogenase, NADP-dependen... 677 0.0
ref|XP_001400371.1| precursor of mitochondrial isocitrate d... 677 0.0
ref|XP_459772.1| hypothetical protein DEHA0E11286g [Debaryo... 677 0.0
ref|YP_001832264.1| isocitrate dehydrogenase, NADP-dependen... 677 0.0
gb|AAK76731.1| peroxisomal NADP-dependent isocitrate dehydr... 677 0.0
ref|NP_196963.2| isocitrate dehydrogenase, putative / NADP+... 677 0.0
ref|YP_617009.1| isocitrate dehydrogenase [Sphingopyxis ala... 677 0.0
ref|YP_001849499.1| isocitrate dehydrogenase [NADP] Icd1 [M... 677 0.0
ref|XP_001818331.1| hypothetical protein [Aspergillus oryza... 676 0.0
ref|YP_756242.1| isocitrate dehydrogenase [Maricaulis maris... 676 0.0
ref|ZP_01440188.1| Isocitrate/isopropylmalate dehydrogenase... 676 0.0
ref|ZP_02955422.1| isocitrate dehydrogenase, NADP-dependent... 676 0.0
ref|ZP_03819206.1| isocitrate dehydrogenase (NADP) [Actinos... 676 0.0
ref|YP_001160602.1| isocitrate dehydrogenase [Salinispora t... 676 0.0
emb|CAN72808.1| hypothetical protein [Vitis vinifera] >gi|1... 676 0.0
ref|YP_001419447.1| isocitrate dehydrogenase, NADP-dependen... 676 0.0
ref|YP_001833636.1| isocitrate dehydrogenase, NADP-dependen... 676 0.0
emb|CAG02627.1| unnamed protein product [Tetraodon nigrovir... 676 0.0
ref|NP_175836.1| ICDH; isocitrate dehydrogenase (NADP+) [Ar... 675 0.0
ref|YP_032403.1| isocitrate dehydrogenase [Bartonella quint... 675 0.0
ref|XP_001698704.1| isocitrate dehydrogenase, NADP-dependen... 675 0.0
ref|ZP_02302766.1| isocitrate dehydrogenase, NADP-dependent... 675 0.0
sp|P50215|IDH_SPHYA Isocitrate dehydrogenase [NADP] (Oxalos... 674 0.0
ref|NP_949171.1| isocitrate dehydrogenase [Rhodopseudomonas... 674 0.0
gb|AAR05796.1| NADP+-isocitrate dehydrogenase [Pinus pinaster] 674 0.0
ref|XP_660603.1| IDHP_ASPNG ISOCITRATE DEHYDROGENASE [NADP]... 674 0.0
ref|XP_001646579.1| hypothetical protein Kpol_1055p78 [Vand... 674 0.0
ref|YP_487337.1| isocitrate dehydrogenase [Rhodopseudomonas... 674 0.0
ref|NP_010217.1| Mitochondrial NADP-specific isocitrate deh... 674 0.0
ref|ZP_03922528.1| isocitrate dehydrogenase [Mobiluncus cur... 674 0.0
ref|XP_001650675.1| nadp-specific isocitrate dehydrogenase ... 673 0.0
gb|EAY99113.1| hypothetical protein OsI_020346 [Oryza sativ... 673 0.0
ref|YP_458429.1| isocitrate dehydrogenase [Erythrobacter li... 673 0.0
ref|NP_984921.1| AER061Cp [Ashbya gossypii ATCC 10895] >gi|... 673 0.0
ref|YP_001758392.1| isocitrate dehydrogenase, NADP-dependen... 673 0.0
gb|EAY58582.1| isocitrate dehydrogenase [NADP] icd1 [Mycoba... 673 0.0
ref|YP_001108727.1| isocitrate dehydrogenase [Saccharopolys... 673 0.0
ref|NP_217856.1| isocitrate dehydrogenase [Mycobacterium tu... 673 0.0
ref|YP_682929.1| isocitrate dehydrogenase [Roseobacter deni... 673 0.0
sp|O13285|IDH1_CANTR Isocitrate dehydrogenase [NADP], mitoc... 673 0.0
ref|YP_033790.1| isocitrate dehydrogenase [Bartonella hense... 673 0.0
ref|YP_001296741.1| isocitrate dehydrogenase [Flavobacteriu... 672 0.0
ref|NP_176768.1| isocitrate dehydrogenase, putative / NADP+... 672 0.0
ref|XP_713421.1| cytosolic NADP-specific isocitrate dehydro... 672 0.0
ref|YP_979491.1| isocitrate dehydrogenase [Mycobacterium bo... 672 0.0
ref|ZP_03813993.1| isocitrate dehydrogenase (NADP) [Beutenb... 672 0.0
ref|XP_968850.1| PREDICTED: similar to CG7176-PC, isoform C... 671 0.0
ref|YP_568874.1| isocitrate dehydrogenase [Rhodopseudomonas... 671 0.0
ref|XP_001608101.1| PREDICTED: similar to isocitrate dehydr... 671 0.0
gb|EDU40785.1| isocitrate dehydrogenase, mitochondrial prec... 671 0.0
ref|XP_001484278.1| isocitrate dehydrogenase, mitochondrial... 671 0.0
gb|AAM13090.1| similar to NADP-specific isocitrate dehydrog... 671 0.0
gb|AAM65674.1| isocitrate dehydrogenase, putative [Arabidop... 671 0.0
ref|XP_001527573.1| isocitrate dehydrogenase peroxisomal [L... 671 0.0
ref|YP_001204807.1| isocitrate dehydrogenase [Bradyrhizobiu... 670 0.0
ref|XP_445447.1| unnamed protein product [Candida glabrata]... 670 0.0
ref|YP_001363715.1| isocitrate dehydrogenase, NADP-dependen... 670 0.0
ref|YP_531457.1| isocitrate dehydrogenase [Rhodopseudomonas... 670 0.0
ref|XP_970446.1| PREDICTED: similar to isocitrate dehydroge... 669 0.0
emb|CAD24782.1| isocitrate dehydrogenase [Arabidopsis thali... 669 0.0
ref|YP_001233708.1| isocitrate dehydrogenase [Acidiphilium ... 669 0.0
ref|XP_001176537.1| PREDICTED: similar to Isocitrate dehydr... 669 0.0
emb|CAA63220.1| isocitrate dehydrogenase (NAD+) [Solanum tu... 669 0.0
ref|YP_062774.1| isocitrate dehydrogenase [Leifsonia xyli s... 669 0.0
ref|YP_001260963.1| isocitrate dehydrogenase [Sphingomonas ... 669 0.0
ref|NP_982520.1| AAL022Wp [Ashbya gossypii ATCC 10895] >gi|... 669 0.0
ref|YP_001709366.1| isocitrate dehydrogenase [Clavibacter m... 669 0.0
emb|CAO64975.1| unnamed protein product [Vitis vinifera] 669 0.0
ref|ZP_00954676.1| isocitrate dehydrogenase [Sulfitobacter ... 669 0.0
ref|YP_001223282.1| isocitrate dehydrogenase [Clavibacter m... 669 0.0
ref|ZP_00964081.1| isocitrate dehydrogenase [Sulfitobacter ... 668 0.0
ref|XP_312860.4| AGAP003168-PA [Anopheles gambiae str. PEST... 668 0.0
ref|NP_001042583.1| Os01g0248400 [Oryza sativa (japonica cu... 668 0.0
ref|YP_001241304.1| isocitrate dehydrogenase [Bradyrhizobiu... 668 0.0
ref|ZP_00206729.1| COG0538: Isocitrate dehydrogenases [Bifi... 668 0.0
emb|CAB87626.1| isocitrate dehydrogenase-like protein [Arab... 668 0.0
ref|ZP_01046178.1| isocitrate dehydrogenase NADP-dependent ... 667 0.0
ref|YP_780531.1| isocitrate dehydrogenase [Rhodopseudomonas... 667 0.0
ref|ZP_03993927.1| isocitrate dehydrogenase [Mobiluncus mul... 667 0.0
ref|YP_317907.1| isocitrate dehydrogenase [Nitrobacter wino... 667 0.0
ref|NP_696658.1| isocitrate dehydrogenase [Bifidobacterium ... 667 0.0
ref|ZP_03896321.1| isocitrate dehydrogenase (NADP) [Dyadoba... 667 0.0
ref|YP_989041.1| isocitrate dehydrogenase [Bartonella bacil... 667 0.0
ref|YP_001169228.1| isocitrate dehydrogenase [Rhodobacter s... 666 0.0
ref|YP_909639.1| isocitrate dehydrogenase [Bifidobacterium ... 666 0.0
ref|ZP_03977360.1| isocitrate dehydrogenase (NADP(+)) [Bifi... 666 0.0
ref|XP_001837820.1| hypothetical protein CC1G_11465 [Coprin... 666 0.0
ref|NP_962389.1| isocitrate dehydrogenase [Mycobacterium av... 666 0.0
ref|YP_001168561.1| isocitrate dehydrogenase [Rhodobacter s... 666 0.0
ref|YP_001601185.1| Isocitrate dehydrogenase [Gluconacetoba... 665 0.0
ref|YP_759895.1| isocitrate dehydrogenase [Hyphomonas neptu... 665 0.0
ref|NP_001040134.1| isocitrate dehydrogenase [Bombyx mori] ... 665 0.0
ref|YP_576902.1| isocitrate dehydrogenase [Nitrobacter hamb... 664 0.0
ref|ZP_01018081.1| isocitrate dehydrogenase [Parvularcula b... 664 0.0
gb|ACO14957.1| Isocitrate dehydrogenase cytoplasmic [Caligu... 664 0.0
gb|ABL97438.1| isocitrate dehydrogenase [uncultured marine ... 664 0.0
ref|YP_883449.1| isocitrate dehydrogenase [Mycobacterium av... 664 0.0
ref|NP_013275.1| Cytosolic NADP-specific isocitrate dehydro... 664 0.0
ref|ZP_02981592.1| isocitrate dehydrogenase, NADP-dependent... 664 0.0
ref|XP_001485076.1| isocitrate dehydrogenase peroxisomal [P... 663 0.0
ref|YP_001043974.1| isocitrate dehydrogenase [Rhodobacter s... 663 0.0
gb|ABI52605.1| isocitrate dehydrogenase [Gryllus firmus] 663 0.0
ref|XP_001457045.1| hypothetical protein GSPATT00022820001 ... 663 0.0
ref|XP_001270886.1| isocitrate dehydrogenase Idp1, putative... 663 0.0
gb|EDN59398.1| NADP-dependent isocitrate dehydrogenase [Sac... 663 0.0
ref|XP_821599.1| isocitrate dehydrogenase, putative [Trypan... 662 0.0
ref|YP_001042101.1| isocitrate dehydrogenase [Rhodobacter s... 662 0.0
ref|XP_001676039.1| Hypothetical protein CBG17397 [Caenorha... 662 0.0
ref|XP_001426548.1| hypothetical protein GSPATT00029781001 ... 662 0.0
ref|XP_001878769.1| predicted protein [Laccaria bicolor S23... 662 0.0
ref|YP_353519.1| isocitrate dehydrogenase [Rhodobacter spha... 662 0.0
ref|YP_351602.1| isocitrate dehydrogenase [Rhodobacter spha... 661 0.0
ref|ZP_01157336.1| isocitrate dehydrogenase [Oceanicola gra... 661 0.0
ref|ZP_00960755.1| Isocitrate dehydrogenase [Roseovarius nu... 661 0.0
ref|XP_445184.1| unnamed protein product [Candida glabrata]... 660 0.0
ref|XP_001383685.1| Isocitrate dehydrogenase [NADP] peroxis... 660 0.0
ref|XP_460289.1| hypothetical protein DEHA0E24134g [Debaryo... 659 0.0
ref|XP_623673.2| PREDICTED: similar to Isocitrate dehydroge... 659 0.0
sp|O13294|IDH2_CANTR Isocitrate dehydrogenase [NADP] peroxi... 659 0.0
ref|NP_001053269.1| Os04g0508200 [Oryza sativa (japonica cu... 659 0.0
ref|NP_509875.1| C34F6.8 [Caenorhabditis elegans] >gi|38747... 658 0.0
ref|XP_001020930.2| dehydrogenase, isocitrate/isopropylmala... 658 0.0
ref|NP_926944.1| isocitrate dehydrogenase [Gloeobacter viol... 658 0.0
ref|XP_001670101.1| Hypothetical protein CBG21657 [Caenorha... 657 0.0
emb|CAE04728.1| OSJNBa0043L24.16 [Oryza sativa (japonica cu... 657 0.0
ref|ZP_02963068.1| isocitrate dehydrogenase [Bifidobacteriu... 656 0.0
ref|XP_455638.1| unnamed protein product [Kluyveromyces lac... 656 0.0
ref|ZP_01130474.1| isocitrate dehydrogenase [marine actinob... 656 0.0
ref|XP_001845030.1| isocitrate dehydrogenase [Culex pipiens... 655 0.0
ref|XP_001462393.1| hypothetical protein GSPATT00027349001 ... 655 0.0
ref|ZP_01751534.1| isocitrate dehydrogenase [Roseobacter sp... 655 0.0
ref|ZP_02918686.1| hypothetical protein BIFDEN_01996 [Bifid... 655 0.0
ref|XP_001454244.1| hypothetical protein GSPATT00020509001 ... 655 0.0
emb|CAH67563.1| OSIGBa0101P20.6 [Oryza sativa (indica culti... 655 0.0
ref|XP_569234.1| isocitrate dehydrogenase (NADP+) [Cryptoco... 654 0.0
gb|ABO93633.1| isocitrate dehydrogenase 2 [Toxoplasma gondii] 654 0.0
Sequences not found previously or not previously below threshold:
>emb|CAM77136.1| Isocitrate/isopropylmalate dehydrogenase [Magnetospirillum
gryphiswaldense MSR-1]
Length = 405
Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats.
Identities = 254/408 (62%), Positives = 321/408 (78%), Gaps = 5/408 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +PIVE+DGDE TR+IWK IK+KLILPYLDVDLKYYDL ++ RD TNDQVT D+
Sbjct: 1 MNKIKVANPIVELDGDEMTRIIWKFIKDKLILPYLDVDLKYYDLGVEYRDETNDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDEAR+KEFNLK+MWKSPNGTIRNIL GTVFREPII +PRL
Sbjct: 61 AEAIKQYGVGVKCATITPDEARVKEFNLKKMWKSPNGTIRNILDGTVFREPIICQNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPI+IGRHAFGDQYRATD K+ G L ++F +DG + I+ +V+ FP S G+AM
Sbjct: 121 VPGWTKPIVIGRHAFGDQYRATDFKVPGPGILTMKFVGEDG-QVIEHEVFNFP-SSGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N ++SI+GFA+A L +K P++ +TKNTILK YD +FK IF +++KE+K +F
Sbjct: 179 GMYNLDESIRGFARACMNYGLAKKWPVYLSTKNTILKAYDGRFKDIFQEVYEKEFKAEFD 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
+TYEHRLIDDMVA LK G F+ A KNYDGDVQSD VAQGFGSLGLMTS+L++PDG
Sbjct: 239 KYGMTYEHRLIDDMVASALKWSGEFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLSPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+G+ETSTN IASIFAWTR ++ R + DNT +V KF LE
Sbjct: 299 KTVEAEAAHGTVTRHYREHQKGKETSTNPIASIFAWTRGLLYRAQFDNTPEVAKFATALE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMML 408
+ ++TV+ G MTKDLA+++G ++TT +F+D++ + L+ M
Sbjct: 359 EVCVETVE-AGFMTKDLAILIGPDQ--PWLTTTQFLDKLDENLKKKMG 403
>ref|NP_539708.1| isocitrate dehydrogenase [Brucella melitensis 16M]
ref|YP_221903.1| isocitrate dehydrogenase [Brucella abortus biovar 1 str. 9-941]
ref|YP_414607.1| isocitrate dehydrogenase [Brucella melitensis biovar Abortus 2308]
ref|YP_001259118.1| isocitrate dehydrogenase [Brucella ovis ATCC 25840]
ref|YP_001935116.1| Isocitrate/isopropylmalate dehydrogenase [Brucella abortus S19]
gb|AAL51972.1| ISOCITRATE DEHYDROGENASE (NADP) [Brucella melitensis 16M]
gb|AAX74542.1| isocitrate dehydrogenase, NADP-dependent [Brucella abortus biovar 1
str. 9-941]
emb|CAJ11177.1| Isocitrate/isopropylmalate dehydrogenase:Isocitrate dehydrogenase
NADP-dependent, eukaryotic [Brucella melitensis biovar
Abortus 2308]
gb|ABQ61375.1| isocitrate dehydrogenase, NADP-dependent [Brucella ovis ATCC 25840]
gb|ACD72642.1| Isocitrate/isopropylmalate dehydrogenase [Brucella abortus S19]
Length = 404
Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats.
Identities = 260/409 (63%), Positives = 323/409 (78%), Gaps = 5/409 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW+ IK+KLI PYLD+DLKYYDLS++ RD TNDQVT D+
Sbjct: 1 MAKIKVANPVVELDGDEMTRIIWQFIKDKLIHPYLDIDLKYYDLSVENRDATNDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDEAR++EF LK+MWKSPNGTIRNILGG +FREPII +PRL
Sbjct: 61 ANAIKEYGVGVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGVIFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W +PII+GRHAFGDQYRATD K G L ++F +DG + I+ +VY+ P S G+AM
Sbjct: 121 VPGWTQPIIVGRHAFGDQYRATDFKFPGKGTLTIKFVGEDG-QTIEHEVYQAP-SAGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI+ FA+ASF L+R P++ +TKNTILK YD +FK IF +FD E+K KF+
Sbjct: 179 AMYNLDESIREFARASFNYGLQRGYPVYLSTKNTILKAYDGRFKDIFQEVFDAEFKSKFE 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
KI YEHRLIDDMVA LK GG++ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 239 EKKIWYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+GEETSTNSIASIFAWTR + R KLDN D+ KF LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGLAHRAKLDNNADLKKFAETLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
K +DTV+ G MTKDLAL++G +++T F+D++ + LQ M +
Sbjct: 359 KVCVDTVE-SGFMTKDLALLIGPDQ--PWLSTTGFLDKIDENLQKAMAA 404
>ref|NP_698203.1| isocitrate dehydrogenase [Brucella suis 1330]
ref|YP_001593041.1| isocitrate dehydrogenase, NADP-dependent [Brucella canis ATCC
23365]
ref|YP_001627868.1| isocitrate dehydrogenase, NADP-dependent [Brucella suis ATCC 23445]
gb|AAN30118.1| isocitrate dehydrogenase, NADP-dependent [Brucella suis 1330]
gb|ABX62270.1| isocitrate dehydrogenase, NADP-dependent [Brucella canis ATCC
23365]
gb|ABY38298.1| isocitrate dehydrogenase, NADP-dependent [Brucella suis ATCC 23445]
Length = 404
Score = 703 bits (1814), Expect = 0.0, Method: Composition-based stats.
Identities = 259/409 (63%), Positives = 323/409 (78%), Gaps = 5/409 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW+ IK+KLI PYLD+DLKYYDLS++ RD TNDQVT D+
Sbjct: 1 MAKIKVANPVVELDGDEMTRIIWQFIKDKLIHPYLDIDLKYYDLSVENRDATNDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDEAR++EF LK+MWKSPNGTIRNILGG +FREPII +PRL
Sbjct: 61 ANAIKEYGVGVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGVIFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W +PII+GRHAFGDQYRATD K G L ++F +DG + I+ +VY+ P S G+AM
Sbjct: 121 VPGWTQPIIVGRHAFGDQYRATDFKFPGKGTLTIKFVGEDG-QTIEHEVYQAP-SAGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI+ FA+ASF L+R P++ +TKNTILK YD +FK IF +FD E+K KF+
Sbjct: 179 AMYNLDESIREFARASFNYGLQRGYPVYLSTKNTILKAYDGRFKDIFQEVFDAEFKSKFE 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
KI YEHRLIDDMVA LK GG++ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 239 EKKIWYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R++Q+GEETSTNSIASIFAWTR + R KLDN D+ KF LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQYQKGEETSTNSIASIFAWTRGLAHRAKLDNNADLKKFAETLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
K +DTV+ G MTKDLAL++G +++T F+D++ + LQ M +
Sbjct: 359 KVCVDTVE-SGFMTKDLALLIGPDQ--PWLSTTGFLDKIDENLQKAMAA 404
>ref|XP_001903959.1| unnamed protein product [Podospora anserina]
emb|CAP61736.1| unnamed protein product [Podospora anserina]
Length = 461
Score = 701 bits (1811), Expect = 0.0, Method: Composition-based stats.
Identities = 272/407 (66%), Positives = 330/407 (81%), Gaps = 1/407 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TRVIW+ IK+K I PYLD+DLKYYDL ++ RD+TNDQVT D++
Sbjct: 53 AKIKVKNPVVELDGDEMTRVIWQDIKDKFITPYLDIDLKYYDLGLEYRDQTNDQVTIDAA 112
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KY V VKCATITPDEAR++EF LK+MW SPNGTIRN LGGTVFREPI+IP++PRLV
Sbjct: 113 EAIKKYSVGVKCATITPDEARVEEFKLKQMWLSPNGTIRNALGGTVFREPIVIPRVPRLV 172
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPIIIGRHAFGDQYRA D GKL + ++ + G E +++VY+F GG+A
Sbjct: 173 PGWKKPIIIGRHAFGDQYRAKDFVAPGPGKLSMVYTPE-GGEPQEIEVYKFQGGGGVAQT 231
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT++SI GFA ASF+LA+ + LPL+ +TKNTILK YD +FK IF L+D +YKE F+A
Sbjct: 232 QYNTDESITGFAHASFKLAIDKGLPLYMSTKNTILKKYDGRFKDIFQELYDTQYKEAFEA 291
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS GG+I+A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGK
Sbjct: 292 KGIWYEHRLIDDMVAQMIKSSGGYIMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGK 351
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
TFESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD+T +V+ F LEK
Sbjct: 352 TFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDDTPEVVAFAEALEK 411
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMML 408
A +DTV V G MTKDLAL GKT R YVTT E++ V +RL+ +
Sbjct: 412 ACIDTVDVDGIMTKDLALACGKTGREDYVTTSEYMVAVERRLKQSLK 458
>ref|XP_536192.2| PREDICTED: similar to isocitrate dehydrogenase 2 (NADP+),
mitochondrial [Canis familiaris]
Length = 517
Score = 699 bits (1806), Expect = 0.0, Method: Composition-based stats.
Identities = 253/411 (61%), Positives = 309/411 (75%), Gaps = 6/411 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 109 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 168
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 169 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 228
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD + +AG ++ FS DG + +VY FP GG+ M M
Sbjct: 229 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKIIFSPKDGSGAKEWEVYNFP-GGGVGMGM 287
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +F+K YK F
Sbjct: 288 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKN 347
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 348 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 407
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 408 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 467
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLS 409
+ TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 468 CVQTVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKNNLDKALGQ 517
>ref|XP_001226620.1| conserved hypothetical protein [Chaetomium globosum CBS 148.51]
gb|EAQ84679.1| conserved hypothetical protein [Chaetomium globosum CBS 148.51]
Length = 469
Score = 699 bits (1805), Expect = 0.0, Method: Composition-based stats.
Identities = 273/407 (67%), Positives = 328/407 (80%), Gaps = 1/407 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TRVIWK IKEK I PYLDVDLKYYDL ++ RD TNDQVT D++
Sbjct: 61 AKIKVKNPVVELDGDEMTRVIWKDIKEKFIFPYLDVDLKYYDLGLEYRDETNDQVTLDAA 120
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KY V VKCATITPDEAR++EF LK+MW SPNGTIRN LGGTVFREPI+IP+IPRLV
Sbjct: 121 EAIKKYSVGVKCATITPDEARVEEFKLKQMWLSPNGTIRNALGGTVFREPIVIPRIPRLV 180
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPIIIGRHAFGDQYRA D+ + GKL + ++ G E +++V++F GG+A
Sbjct: 181 PGWKKPIIIGRHAFGDQYRAKDLVVPGPGKLSMVYTPA-GGEPQEIEVFQFKNGGGVAQT 239
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT++SI GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF L+D YK +F+A
Sbjct: 240 QYNTDESITGFAHASFKLALDKGLPLYMSTKNTILKKYDGRFKDIFQELYDGGYKAQFEA 299
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS GG+I+A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGK
Sbjct: 300 KGIWYEHRLIDDMVAQMIKSTGGYIMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGK 359
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
TFESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T +V+ F LE+
Sbjct: 360 TFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPEVVAFAEGLER 419
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMML 408
A +DTV + G MTKDLAL GKT R YVTT E++ V +RL+ +
Sbjct: 420 ACIDTVDIDGIMTKDLALACGKTAREDYVTTSEYLSAVERRLKQSLK 466
>ref|XP_955850.1| hypothetical protein NCU03857 [Neurospora crassa OR74A]
gb|EAA26614.1| hypothetical protein NCU03857 [Neurospora crassa OR74A]
Length = 462
Score = 699 bits (1804), Expect = 0.0, Method: Composition-based stats.
Identities = 266/407 (65%), Positives = 332/407 (81%), Gaps = 1/407 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
KIKV +P+VE+DGDE TR+IW+ IKEK I P+LD+DLKYYDL ++ RD+TNDQVT D++
Sbjct: 54 QKIKVKNPVVELDGDEMTRIIWQDIKEKFIYPFLDIDLKYYDLGLEYRDQTNDQVTIDAA 113
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KY V VKCATITPDE+R++EF LK+MW SPNGTIRN LGGTVFREPI+IP++PRLV
Sbjct: 114 EAIKKYSVGVKCATITPDESRVEEFKLKQMWLSPNGTIRNALGGTVFREPIVIPRVPRLV 173
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPIIIGRHAFGDQYRA D+ GKL++ ++ + G E + V+++ GG+A
Sbjct: 174 PGWKKPIIIGRHAFGDQYRAKDLVAPGPGKLQMVYTPE-GGEPQVIDVFDYKNGGGVAQT 232
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT++SI+GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF ++D +YKE F+A
Sbjct: 233 QYNTDESIEGFAHASFKLALDKGLPLYMSTKNTILKKYDGRFKDIFQQIYDTQYKEAFEA 292
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQM+KS GG+I+A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGK
Sbjct: 293 KKIWYEHRLIDDMVAQMIKSSGGYIMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGK 352
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
TFESEAAHGTVTRH+R+HQ+G +TSTN IASIFAWTR ++QRGKLDNT ++I F LEK
Sbjct: 353 TFESEAAHGTVTRHYREHQKGNQTSTNPIASIFAWTRGLVQRGKLDNTPELIAFAEALEK 412
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMML 408
A +DTV + G MTKDLAL GKT R +VTT E++ V +RL++ +
Sbjct: 413 ACIDTVDIDGIMTKDLALACGKTGREDWVTTSEYMAAVERRLKSTLK 459
>gb|EEJ98364.1| isocitrate dehydrogenase (NADP) [Thermomonospora curvata DSM 43183]
Length = 407
Score = 699 bits (1804), Expect = 0.0, Method: Composition-based stats.
Identities = 254/407 (62%), Positives = 317/407 (77%), Gaps = 3/407 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M KIKV P+VE+DGDE TR+IWK IK++LILPYLD+DLKYYDL IQ RD T+DQVT D+
Sbjct: 1 MPKIKVAGPVVELDGDEMTRIIWKFIKDQLILPYLDIDLKYYDLGIQNRDATDDQVTVDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR++EF LK+MW+SPNGTIRNILGG VFREPII+ IPRL
Sbjct: 61 ANAIKKYGVGVKCATITPDEARVEEFGLKQMWRSPNGTIRNILGGVVFREPIIVSNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPI+IGRHA GDQY+ATD K+ G L + ++ DDG E I +V +P+ GG+AM
Sbjct: 121 VPGWTKPIVIGRHAHGDQYKATDFKVPGPGTLTITYTPDDGSEPIQFEVARYPEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N SI+ FA+ASF L R P++ +TKNTILK YD FK +F +++ E+KE+F+
Sbjct: 181 GMYNFRKSIEDFARASFRYGLDRNYPVYLSTKNTILKAYDGMFKDVFAEIYENEFKEEFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A +TYEHRLIDDMVA LK +GG++ A KNYDGDVQSD VAQGFGSLGLMTS+L+TPDG
Sbjct: 241 ARGLTYEHRLIDDMVACALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+T E+EAAHGTVTRH+R HQ+G+ TSTN IASIFAWTR + RGKLDNT +VIKF LE
Sbjct: 301 RTVEAEAAHGTVTRHYRLHQQGKPTSTNPIASIFAWTRGLAHRGKLDNTPEVIKFAETLE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
+ ++TV+ G+MTKDLAL++ K ++TT+EF+ + LQ +
Sbjct: 361 QVCIETVE-SGQMTKDLALLISKDQ--PWLTTQEFLHALDVNLQKKI 404
>ref|NP_786984.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Bos taurus]
emb|CAA49207.1| isocitrate dehydrogenase (NADP+) [Bos taurus]
Length = 452
Score = 698 bits (1803), Expect = 0.0, Method: Composition-based stats.
Identities = 252/412 (61%), Positives = 312/412 (75%), Gaps = 6/412 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD + +AG ++ F+ DG + +VY FP +GG+ M M
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFP-AGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +F+K YK +F
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDKH 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 402 CVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGQQ 452
>sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAI02510.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Bos taurus]
Length = 452
Score = 698 bits (1803), Expect = 0.0, Method: Composition-based stats.
Identities = 252/412 (61%), Positives = 312/412 (75%), Gaps = 6/412 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD + +AG ++ F+ DG + +VY FP +GG+ M M
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFP-AGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +F+K YK +F
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDKH 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 402 CVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGQQ 452
>gb|ACO14046.1| Isocitrate dehydrogenase, mitochondrial precursor [Esox lucius]
Length = 451
Score = 698 bits (1803), Expect = 0.0, Method: Composition-based stats.
Identities = 256/411 (62%), Positives = 310/411 (75%), Gaps = 6/411 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLIL +DV+LKYYDL + RD+TNDQVT DS+
Sbjct: 43 RIKVSQPVVEMDGDEMTRIIWEFIKEKLILSNVDVELKYYDLGLPYRDQTNDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYHVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W +PI IGRHAFGDQYRATD + + G ++ FS DG + + VY FP GG M M
Sbjct: 163 GWTQPITIGRHAFGDQYRATDFVVNQPGTFKMVFSPTDGSKGQEWGVYNFP-GGGCGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+ +K PL+ +TKNTILK YD +FK IF+ +F YK +F L
Sbjct: 222 YNTDESISGFAHSCFQYAIGKKWPLYLSTKNTILKAYDGRFKDIFEEIFQANYKPEFDKL 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS G F+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSDGAFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+IKF LE+
Sbjct: 342 IEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRGKLDGNPDLIKFALTLERV 401
Query: 363 TLDTVQVGGKMTKDLALMLGKTNR----SSYVTTEEFIDEVAKRLQNMMLS 409
++TV+ G MTKDLA + ++ YV TE+F+D + K L +
Sbjct: 402 CVETVE-SGVMTKDLAGCIHGLSKCKLNEHYVNTEDFLDAIKKNLDKALGK 451
>ref|NP_001026770.1| hypothetical protein LOC431056 [Gallus gallus]
emb|CAG31511.1| hypothetical protein [Gallus gallus]
Length = 452
Score = 698 bits (1802), Expect = 0.0, Method: Composition-based stats.
Identities = 252/411 (61%), Positives = 311/411 (75%), Gaps = 6/411 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV +P+VEMDGDE TR+IW IKEKLILP +DV LKY+DL + RD+T+DQVT DS+
Sbjct: 43 RIKVANPVVEMDGDEMTRIIWAFIKEKLILPNVDVQLKYFDLGLPHRDKTDDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATKKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W +PI IGRHA GDQY+ATD + K+G ++ F+ DG + +V+ FP GG+ M M
Sbjct: 163 GWTQPITIGRHAHGDQYKATDFVVNKSGTFKMVFTPKDGSGVKEWEVFNFP-GGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK +F L
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTEFDKL 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD+ ++IKF LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDSNPELIKFAQTLEKV 401
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLS 409
++TV+ G MTKDLA + +V T +F+D + L +
Sbjct: 402 CVETVE-SGTMTKDLAGCIHGLANVKLNEHFVNTTDFLDAIKNTLDKALGK 451
>ref|NP_970434.1| isocitrate dehydrogenase [Bdellovibrio bacteriovorus HD100]
emb|CAE81088.1| isocitrate dehydrogenase (NADP) [Bdellovibrio bacteriovorus HD100]
Length = 409
Score = 698 bits (1802), Expect = 0.0, Method: Composition-based stats.
Identities = 255/409 (62%), Positives = 314/409 (76%), Gaps = 4/409 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M KIKV +P+VE+DGDE TR+IWK IK++LILPYLD+D+KYYDL ++ RD TNDQVT D+
Sbjct: 1 MKKIKVANPVVELDGDEMTRIIWKFIKQQLILPYLDIDIKYYDLGMEHRDATNDQVTVDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V +KCATITPDEAR+KEFNLK+MWKSPNGTIRNIL GTVFREPII +PRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEARVKEFNLKQMWKSPNGTIRNILDGTVFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP+W PI IGRHAFGDQYRATD K GKL + F ++G E I +VY F K G+A+
Sbjct: 121 VPNWTAPICIGRHAFGDQYRATDFVTKGKGKLTVTFQPENGGETITHEVYNF-KGDGVAL 179
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+NT++SI GFA++ F AL +K PL+ +TKNTILK YD +FK IF+ ++ KE+K KF
Sbjct: 180 TMYNTDESITGFARSCFNQALTKKWPLYLSTKNTILKKYDGRFKDIFEEIYQKEFKAKFD 239
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A ITYEHRLIDDMVA LK G F+ A KNYDGDVQSD VAQGFGSLGLMTS+L+TPDG
Sbjct: 240 AAGITYEHRLIDDMVASALKWNGNFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLVTPDG 299
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT ESEAAHGTVTRH+R+HQ+G+ TSTN IASIFAWTR + RG LDN +++KF LE
Sbjct: 300 KTMESEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLEHRGNLDNNQELVKFAQTLE 359
Query: 361 KATLDTVQVGGKMTKDLALML--GKTNRSSYVTTEEFIDEVAKRLQNMM 407
K ++TV+ G MTKDLA+ + K Y+ TE F+ ++ + L+ +
Sbjct: 360 KVCVETVE-AGFMTKDLAVCIYGDKVPADKYMNTEPFLAKLDENLKKAL 407
>ref|XP_421965.2| PREDICTED: similar to cytosolic NADP-dependent isocitrate
dehydrogenase [Gallus gallus]
Length = 415
Score = 698 bits (1801), Expect = 0.0, Method: Composition-based stats.
Identities = 245/412 (59%), Positives = 306/412 (74%), Gaps = 4/412 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TRVIW+LIKEKLI PY+D+DL YDL I+ RD TND+VT ++
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIEHRDATNDKVTVEA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V +KCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYHVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPI+IGRHA+GDQYRATD + GK+ + ++ DG + + V+ F GG+AM
Sbjct: 121 VSGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEMTYTPGDGGKPVTYLVHNFESCGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SIK FA +SF++AL + PL+ +TKNTILK YD +FK IF ++D+EYK +F+
Sbjct: 181 GMYNLDQSIKDFAHSSFQMALSKGWPLYMSTKNTILKRYDGRFKDIFQEIYDREYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ LKS+GGF+ A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G+ETSTN IASIFAWTR + R KLDN + F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWTRGLAHRAKLDNNTSLKTFATALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLS 409
+ ++T++ G MTKDLA + RS Y+ T EF+D++A L+ + S
Sbjct: 361 EVCIETIE-SGFMTKDLAACIKGLPNVTRSDYLNTFEFMDKLAANLKGKLAS 411
>gb|ABU41004.1| isocitrate dehydrogenase 1 [Anser anser]
Length = 415
Score = 698 bits (1801), Expect = 0.0, Method: Composition-based stats.
Identities = 246/412 (59%), Positives = 307/412 (74%), Gaps = 4/412 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TRVIW+LIKEKLI PY+D+DL YDL I+ RD TND+VT ++
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIEHRDATNDKVTVEA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V +KCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYHVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPI+IGRHA+GDQYRATD + GK+ + ++ DG + + V+ F GG+AM
Sbjct: 121 VSGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEMTYTPGDGGKPVTYLVHNFESCGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
MFN + SIK FA +SF++AL + PL+ +TKNTILK YD +FK IF ++D+EYK +F+
Sbjct: 181 GMFNLDQSIKDFAHSSFQMALSKGWPLYMSTKNTILKRYDGRFKDIFQEIYDREYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ LKS+GGF+ A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G+ETSTN IASIFAWTR + R KLDN + F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWTRGLAHRAKLDNNTSLKTFAAALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLS 409
+ ++T++ G MTKDLA + RS Y+ T EF+D++A+ L+ + S
Sbjct: 361 EVCIETIE-SGFMTKDLAACIKGLPNVTRSDYLNTFEFMDKLAENLKGKLAS 411
>ref|NP_955858.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Danio rerio]
gb|AAH48041.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Danio rerio]
gb|AAH63967.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Danio rerio]
Length = 449
Score = 697 bits (1799), Expect = 0.0, Method: Composition-based stats.
Identities = 252/411 (61%), Positives = 312/411 (75%), Gaps = 6/411 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+I+V P+VEMDGDE TR+IW+ IKEKLIL ++VDLKYYDL + RD+T+DQVT DS+
Sbjct: 41 RIQVAQPVVEMDGDEMTRIIWEFIKEKLILTNVNVDLKYYDLGLPYRDQTDDQVTIDSAI 100
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 101 ATKKYNVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 160
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W + I IGRHAFGDQY+ATD + + GK ++ F+ DG +N + +VY+FP GG M M
Sbjct: 161 GWTQAITIGRHAFGDQYKATDFVVNQPGKFKMVFTPADGSKNKEWEVYDFP-GGGCGMGM 219
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF ++F+K YK +F L
Sbjct: 220 YNTDESITGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQDIFEKNYKPEFDKL 279
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS G F+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 280 KIWYEHRLIDDMVAQVLKSSGAFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 339
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+IKF LE+
Sbjct: 340 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNPDLIKFSQTLERV 399
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLS 409
++TV+ G MTKDLA + YV T +F+D + L +
Sbjct: 400 CVETVE-SGVMTKDLAGCIHGLANCKLNEHYVNTTDFLDAIKTNLDKALGK 449
>sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02924.1| cytosolic NADP-dependent isocitrate dehydrogenase [Microtus
mexicanus]
Length = 414
Score = 697 bits (1799), Expect = 0.0, Method: Composition-based stats.
Identities = 245/414 (59%), Positives = 310/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLILPY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + F+ DG + + V+ F + GG+AM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITFTPKDGSQKVTYLVHSFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G+ETSTN IASIFAW+R + R +LDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVCIETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAK 413
>sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
dbj|BAC40149.1| unnamed protein product [Mus musculus]
gb|AAH60030.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Mus musculus]
dbj|BAE41142.1| unnamed protein product [Mus musculus]
dbj|BAE36505.1| unnamed protein product [Mus musculus]
dbj|BAE26628.1| unnamed protein product [Mus musculus]
gb|EDL07035.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial, isoform CRA_d
[Mus musculus]
Length = 452
Score = 696 bits (1797), Expect = 0.0, Method: Composition-based stats.
Identities = 253/412 (61%), Positives = 310/412 (75%), Gaps = 6/412 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 43 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD + +AG +L F+ DG + +VY FP +GG+ M M
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFP-AGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ ++++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 222 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
+ TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 402 CVQTVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ 452
>gb|ABE98244.1| mitochondrial isocitrate dehydrogenase 2-like [Oreochromis
mossambicus]
Length = 452
Score = 696 bits (1797), Expect = 0.0, Method: Composition-based stats.
Identities = 253/411 (61%), Positives = 313/411 (76%), Gaps = 6/411 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV +P+VEMDGDE TR+IW+ IKEKLIL +DV+LKY+DL + RD+T+DQVT DS+
Sbjct: 44 RIKVANPVVEMDGDEMTRIIWEFIKEKLILTNVDVELKYFDLGLPYRDQTDDQVTIDSAL 103
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 104 ATKKYSVAVKCATITPDEARVEEFGLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 163
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W +PI IGRHAFGDQYRATD + + GK ++ FS DG + + +V++FP +GG M M
Sbjct: 164 GWTQPITIGRHAFGDQYRATDFVVDQPGKFKIVFSPADGSTSKEWEVFDFP-AGGCGMGM 222
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+ +K PL+ +TKNTILK YD +FK IF ++F+K YK +F L
Sbjct: 223 YNTDESITGFAHSCFQYAIGKKWPLYMSTKNTILKAYDGRFKDIFQDIFEKNYKPEFDKL 282
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS G F+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 283 KIWYEHRLIDDMVAQVLKSSGAFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 342
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+IKF LE+
Sbjct: 343 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNPDLIKFAQTLEQV 402
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLS 409
+ TV+ G MTKDLA + + YV T +F+D + L +
Sbjct: 403 CVATVE-SGTMTKDLAGCIHGLSNVKLNEHYVNTTDFLDAIKTNLDKALGK 452
>sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02925.1| cytosolic NADP-dependent isocitrate dehydrogenase [Microtus
ochrogaster]
Length = 414
Score = 696 bits (1797), Expect = 0.0, Method: Composition-based stats.
Identities = 244/414 (58%), Positives = 310/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLILPY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHSFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G+ETSTN IASIFAW+R + R +LDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVCIETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAK 413
>ref|XP_001107627.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 1
[Macaca mulatta]
ref|XP_001107810.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 2
[Macaca mulatta]
ref|XP_001107875.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 3
[Macaca mulatta]
ref|XP_001107934.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 4
[Macaca mulatta]
ref|XP_001107992.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 5
[Macaca mulatta]
Length = 414
Score = 696 bits (1797), Expect = 0.0, Method: Composition-based stats.
Identities = 243/414 (58%), Positives = 311/414 (75%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VE+ GDE TR+IW+LIKEKLI PY+++DL+ YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKISGGSVVELQGDEMTRIIWELIKEKLIFPYVELDLQSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVCIETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>ref|XP_754749.1| isocitrate dehydrogenase Idp1 [Aspergillus fumigatus Af293]
gb|EAL92711.1| isocitrate dehydrogenase Idp1, putative [Aspergillus fumigatus
Af293]
Length = 501
Score = 696 bits (1796), Expect = 0.0, Method: Composition-based stats.
Identities = 266/408 (65%), Positives = 333/408 (81%), Gaps = 2/408 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TR+IW+ I+EKLILPYLD+DLKYYDL I+ RD+T+D+VT +++
Sbjct: 94 TKIKVKNPVVELDGDEMTRIIWQEIREKLILPYLDIDLKYYDLGIEYRDQTDDKVTVEAA 153
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRLV
Sbjct: 154 EAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRLV 213
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPIIIGRHAFGDQYRATDI + GKL L ++ ++G E +KVY+F GG+A
Sbjct: 214 PGWNKPIIIGRHAFGDQYRATDIVVPGPGKLELVYTPENG-EPQAIKVYDFT-GGGVAQT 271
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT+DSI+GFA +SF++AL + LPL+ +TKNTILK YD +FK IF +++ YK++F A
Sbjct: 272 QYNTDDSIRGFAHSSFKMALMKGLPLYMSTKNTILKKYDGRFKDIFQEIYESTYKKEFDA 331
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS+GGF++A+KNYDGDVQSD+VAQGFGSLGLMTS L TPDG
Sbjct: 332 KGIWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDVVAQGFGSLGLMTSTLTTPDGS 391
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+ F LE+
Sbjct: 392 AFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVTFAEELER 451
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
A +D V G MTKDLAL G+ R ++VTT+E++ V +RL++ + +
Sbjct: 452 ACIDVVNEEGIMTKDLALACGRKEREAWVTTKEYLAAVERRLKSNLKA 499
>gb|EDP52872.1| isocitrate dehydrogenase Idp1, putative [Aspergillus fumigatus
A1163]
Length = 501
Score = 696 bits (1796), Expect = 0.0, Method: Composition-based stats.
Identities = 266/408 (65%), Positives = 333/408 (81%), Gaps = 2/408 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TR+IW+ I+EKLILPYLD+DLKYYDL I+ RD+T+D+VT +++
Sbjct: 94 TKIKVKNPVVELDGDEMTRIIWQEIREKLILPYLDIDLKYYDLGIEYRDQTDDKVTVEAA 153
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRLV
Sbjct: 154 EAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRLV 213
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPIIIGRHAFGDQYRATDI + GKL L ++ ++G E +KVY+F GG+A
Sbjct: 214 PGWNKPIIIGRHAFGDQYRATDIVVPGPGKLELVYTPENG-EPQAIKVYDFT-GGGVAQT 271
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT+DSI+GFA +SF++AL + LPL+ +TKNTILK YD +FK IF +++ YK++F A
Sbjct: 272 QYNTDDSIRGFAHSSFKMALMKGLPLYMSTKNTILKKYDGRFKDIFQEIYESTYKKEFDA 331
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS+GGF++A+KNYDGDVQSD+VAQGFGSLGLMTS L TPDG
Sbjct: 332 KGIWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDVVAQGFGSLGLMTSTLTTPDGS 391
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+ F LE+
Sbjct: 392 AFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVTFAEELER 451
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
A +D V G MTKDLAL G+ R ++VTT+E++ V +RL++ + +
Sbjct: 452 ACIDVVNEEGIMTKDLALACGRKEREAWVTTKEYLAAVERRLKSNLKA 499
>ref|YP_002826161.1| NADP isocitrate dehydrogenase [Rhizobium sp. NGR234]
gb|ACP25408.1| NADP isocitrate dehydrogenase [Rhizobium sp. NGR234]
Length = 404
Score = 696 bits (1796), Expect = 0.0, Method: Composition-based stats.
Identities = 255/409 (62%), Positives = 326/409 (79%), Gaps = 5/409 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW+ IK+KLI PYLD+DL+YYDLS++ RD T DQVT D+
Sbjct: 1 MAKIKVANPVVELDGDEMTRIIWQFIKDKLIHPYLDLDLEYYDLSVENRDATEDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A ++GV VKCATITPDEAR++EF+LK+MWKSPNGTIRNILGG +FREPII +PRL
Sbjct: 61 ANAIKEHGVGVKCATITPDEARVEEFSLKKMWKSPNGTIRNILGGVIFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPII+GRHAFGDQYRATD K GKL ++F +DGKE I+ V++ P S G+AM
Sbjct: 121 VPGWTKPIIVGRHAFGDQYRATDFKFPGKGKLTMKFVGEDGKE-IEYDVFDAP-SAGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N +DSI FA+ASF L+RK+P++ +TKNTILK YD +FK IF +FD+E+ E+F+
Sbjct: 179 GMYNLDDSITEFARASFNYGLQRKVPVYLSTKNTILKVYDGRFKDIFQKVFDEEFAEQFK 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A K+ YEHRLIDDMVA LK GG++ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 239 AAKLWYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+GEETSTNSIASIFAWTR + R KLD ++ KF + LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGLAHRAKLDGNSELAKFSDTLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
+ ++TV+ G MTKDLAL++G +++T F+D++ + L+ M +
Sbjct: 359 RVCVETVE-AGFMTKDLALLIGPDQ--PWLSTTGFLDKIDENLKKAMAA 404
>ref|XP_001778805.1| predicted protein [Physcomitrella patens subsp. patens]
gb|EDQ56391.1| predicted protein [Physcomitrella patens subsp. patens]
Length = 411
Score = 696 bits (1796), Expect = 0.0, Method: Composition-based stats.
Identities = 256/409 (62%), Positives = 326/409 (79%), Gaps = 4/409 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KI V +PIVEMDGDE TR+IWK+IK+KLI P+LD+DLKY+DL I+ RD T+D+VT +S+
Sbjct: 4 AKIHVANPIVEMDGDEMTRIIWKMIKDKLIFPFLDLDLKYFDLGIEHRDATDDRVTIESA 63
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR+KE+NLK MW+SPNGTIRNIL GTVFREPI+ IP+LV
Sbjct: 64 EATKKYNVAVKCATITPDEARVKEYNLKSMWRSPNGTIRNILNGTVFREPILCKNIPKLV 123
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W PI IGRHAFGDQY+ATD K GKL++ F ++G E DL VY+F +GG+A+
Sbjct: 124 PGWTSPICIGRHAFGDQYKATDAVFKGPGKLKMVFVPENGGETQDLTVYDFEGAGGVALT 183
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKE-YKEKFQ 240
M+NT++SI+ FA++S +A ++K PL+ +TKNTILK YD +FK IF ++++E +K KF
Sbjct: 184 MYNTDESIRSFAESSMAMAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEQEGWKAKFD 243
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD++AQGFGSLGLMTS+L+ PDG
Sbjct: 244 AAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDMLAQGFGSLGLMTSVLVCPDG 303
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAWTR + RGKLD + ++ F LE
Sbjct: 304 KTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLSHRGKLDGNEKLVDFATKLE 363
Query: 361 KATLDTVQVGGKMTKDLALMLG--KTNRSSYVTTEEFIDEVAKRLQNMM 407
+A + TV+ GKMTKDLAL++ K +R +Y+ TEEFID VA+ L++ +
Sbjct: 364 QACVGTVE-NGKMTKDLALLIHGSKLSRDTYLNTEEFIDAVAEELKSKL 411
>gb|EDN62799.1| NADP-dependent isocitrate dehydrogenase [Saccharomyces cerevisiae
YJM789]
Length = 420
Score = 696 bits (1796), Expect = 0.0, Method: Composition-based stats.
Identities = 419/420 (99%), Positives = 419/420 (99%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS
Sbjct: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL
Sbjct: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDG ENIDLKVYEFPKSGGIAM
Sbjct: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGTENIDLKVYEFPKSGGIAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ
Sbjct: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG
Sbjct: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE
Sbjct: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL 420
KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL
Sbjct: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL 420
>ref|NP_014389.1| Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes
oxidation of isocitrate to alpha-ketoglutarate with the
formation of NADP(H+), required for growth on
unsaturated fatty acids; Idp3p [Saccharomyces
cerevisiae]
sp|P53982|IDHH_YEAST Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase)
(IDH) (NADP(+)-specific ICDH) (IDP)
emb|CAA95869.1| unnamed protein product [Saccharomyces cerevisiae]
gb|AAT93173.1| YNL009W [Saccharomyces cerevisiae]
Length = 420
Score = 695 bits (1795), Expect = 0.0, Method: Composition-based stats.
Identities = 420/420 (100%), Positives = 420/420 (100%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS
Sbjct: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL
Sbjct: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM
Sbjct: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ
Sbjct: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG
Sbjct: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE
Sbjct: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL 420
KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL
Sbjct: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL 420
>ref|XP_001369305.1| PREDICTED: hypothetical protein [Monodelphis domestica]
Length = 455
Score = 695 bits (1795), Expect = 0.0, Method: Composition-based stats.
Identities = 254/411 (61%), Positives = 310/411 (75%), Gaps = 6/411 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+T+DQVT DS+
Sbjct: 46 RIKVDKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPHRDQTDDQVTIDSAL 105
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 106 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 165
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W +PI IGRHA GDQY+ATD + KAG ++ F+ DG + +VY FP +GG+ M M
Sbjct: 166 GWTRPITIGRHAHGDQYKATDFVVDKAGTFKMVFTPKDGSGAKEWEVYNFP-AGGVGMGM 224
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 225 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 284
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 285 KIWYEHRLIDDMVAQVLKSNGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 344
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+IKF LEK
Sbjct: 345 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIKFAQTLEKV 404
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLS 409
+ TV+ G MTKDLA + + Y+ T +F+D + L +
Sbjct: 405 CVQTVE-SGAMTKDLAGCIHGLSNVKLNEHYLNTGDFLDTIKNNLDKALGQ 454
>ref|NP_766599.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Mus musculus]
gb|AAG43538.1|AF212319_1 NADP+-specific isocitrate dehydrogenase [Mus musculus]
Length = 452
Score = 695 bits (1795), Expect = 0.0, Method: Composition-based stats.
Identities = 253/412 (61%), Positives = 310/412 (75%), Gaps = 6/412 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 43 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD + +AG +L F+ DG + +VY FP +GG+ M M
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFP-AGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ ++++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 222 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDRN 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
+ TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 402 CVQTVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ 452
>ref|NP_001009276.1| cytosolic NADP-isocitrate dehydrogenase [Ovis aries]
sp|Q6XUZ5|IDHC_SHEEP Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAP41947.1| cytosolic NADP-isocitrate dehydrogenase [Ovis aries]
Length = 414
Score = 695 bits (1795), Expect = 0.0, Method: Composition-based stats.
Identities = 246/414 (59%), Positives = 307/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS +VEM GDE TR+IW+LIKEKLI PY+D+DL YDLSI+ RD TNDQVTKD+
Sbjct: 1 MSHKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVDLDLHSYDLSIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG V+ F +SGG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEICYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
MFN + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMFNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + LQ + +
Sbjct: 361 EVCIETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAK 413
>ref|NP_851355.2| isocitrate dehydrogenase 1 (NADP+), soluble [Bos taurus]
gb|AAI03369.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Bos taurus]
Length = 414
Score = 695 bits (1795), Expect = 0.0, Method: Composition-based stats.
Identities = 243/414 (58%), Positives = 307/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS+ +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG V+ F +SGG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + LQ + +
Sbjct: 361 EVCIETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAK 413
>ref|NP_001088022.1| hypothetical protein LOC494713 [Xenopus laevis]
gb|AAH82651.1| LOC494713 protein [Xenopus laevis]
Length = 415
Score = 695 bits (1794), Expect = 0.0, Method: Composition-based stats.
Identities = 244/412 (59%), Positives = 308/412 (74%), Gaps = 4/412 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TRVIW LIKEKLILPY+++DL YDL ++ RD T+DQVT D+
Sbjct: 1 MSKKINGGSVVEMQGDEMTRVIWDLIKEKLILPYVELDLHSYDLGMENRDATDDQVTVDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V +KCATITPDE R++EFNLK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEKRVEEFNLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + F+ DG E I ++ F GG+A+
Sbjct: 121 VSGWIKPIIIGRHAYGDQYRATDFVVPGPGKVEISFTPKDGGEAIKYVIHNFEDCGGVAL 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+NT+ SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF +++KEYK +F+
Sbjct: 181 GMYNTDQSIRDFAHSSFQMALSKSWPLYMSTKNTILKRYDGRFKDIFQEIYEKEYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 ENKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G+ETSTN IASIFAW+R + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLDHRAKLDNNQELKNFATALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLS 409
+ ++T++ G MTKDLA + R Y++T EF+D++ + LQ + +
Sbjct: 361 EVCIETIE-AGFMTKDLAACIKGLPNVQRGDYLSTFEFMDKLGENLQLKLAA 411
>ref|YP_001370537.1| isocitrate dehydrogenase, NADP-dependent [Ochrobactrum anthropi
ATCC 49188]
gb|ABS14708.1| isocitrate dehydrogenase, NADP-dependent [Ochrobactrum anthropi
ATCC 49188]
Length = 404
Score = 695 bits (1794), Expect = 0.0, Method: Composition-based stats.
Identities = 254/409 (62%), Positives = 324/409 (79%), Gaps = 5/409 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW+ IK+KLI PYLD+DLKYYDLS++ RD TNDQVT D+
Sbjct: 1 MAKIKVANPVVELDGDEMTRIIWQFIKDKLIHPYLDIDLKYYDLSVEHRDATNDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A ++GV VKCATITPDEAR++EF LK+MWKSPNGTIRNILGG +FREPII +PRL
Sbjct: 61 ANAIKEHGVGVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGVIFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W +PII+GRHAFGDQYRATD K G L ++F +DG E I+ +VY+ P + G+AM
Sbjct: 121 VPGWTQPIIVGRHAFGDQYRATDFKFPGKGTLSIKFVGEDG-ETIEHEVYQAP-AAGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI+ FA+AS L+R P++ +TKNTILK YD +FK IF+ ++ E+ +KF+
Sbjct: 179 AMYNLDESIREFARASLNYGLQRNYPVYLSTKNTILKAYDGRFKDIFEEVYQTEFADKFK 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVA LK GG++ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 239 AAKIWYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+GEETSTNSIASIFAWTR + R KLDN ++ +F + LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGLAHRAKLDNNAELKRFADTLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
K +DTV+ G MTKDLAL++G +++T F+D++ + LQ M +
Sbjct: 359 KVCVDTVE-SGYMTKDLALLIGPDQ--PWLSTTGFLDKIDENLQKAMAA 404
>ref|NP_113698.1| isocitrate dehydrogenase 1 (NADP+), soluble [Rattus norvegicus]
sp|P41562|IDHC_RAT Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAA59356.1| cytosolic NADP-dependent isocitrate dehydrogenase
gb|EDL98861.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98863.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98864.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98865.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
Length = 414
Score = 695 bits (1794), Expect = 0.0, Method: Composition-based stats.
Identities = 245/414 (59%), Positives = 312/414 (75%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS+ +VEM GDE TR+IW+LIKEKLILPY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSRKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V++F + GG+AM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHDFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK KF+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSKFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAW+R + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVCIETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAK 413
>ref|YP_419971.1| isocitrate dehydrogenase [Magnetospirillum magneticum AMB-1]
dbj|BAE49412.1| Isocitrate dehydrogenase [Magnetospirillum magneticum AMB-1]
Length = 406
Score = 694 bits (1793), Expect = 0.0, Method: Composition-based stats.
Identities = 252/408 (61%), Positives = 321/408 (78%), Gaps = 5/408 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +PIVE+DGDE TR+IWK IK+KLILPYLDVDLKYYDL I+ RD+T+D+VT ++
Sbjct: 1 MNKIKVANPIVELDGDEMTRIIWKFIKDKLILPYLDVDLKYYDLGIEYRDKTDDKVTIEA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
S A KYGV VKCATITPDEAR+KEFNLK+MWKSPNGTIRNIL GTVFREPII +PRL
Sbjct: 61 SEAIKKYGVGVKCATITPDEARVKEFNLKKMWKSPNGTIRNILDGTVFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPI+IGRHAFGDQY+ATD + GKL ++F +G E I+ +V++FP G+AM
Sbjct: 121 VPGWTKPIVIGRHAFGDQYKATDFTVPGPGKLTIKFVGTNG-ETIEHEVFDFP-GAGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N ++SI GFA+A ++K P++ +TKNTILK YD +FK IF +++KE+K ++
Sbjct: 179 GMYNLDESIYGFARACLNYGQQKKWPVYLSTKNTILKAYDGRFKDIFQEVYEKEFKAEYA 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
L ITYEHRLIDDMVA LK G F+ A KNYDGDVQSD VAQGFGSLGLMTS+L++PDG
Sbjct: 239 KLGITYEHRLIDDMVASALKWSGEFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMSPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
K E+EAAHGTVTRH+R+HQ+G+ETSTN IASIFAWTR + R + DNT +V KF LE
Sbjct: 299 KVVEAEAAHGTVTRHYREHQKGKETSTNPIASIFAWTRGLFYRAQFDNTPEVAKFAQALE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMML 408
+ ++TV+ G MTKDLA+++G S++TT++F+D++ + L+ M
Sbjct: 359 EVCVETVE-SGFMTKDLAILIGPGQ--SWLTTQQFLDKLDENLKKRMG 403
>ref|XP_001240510.1| isocitrate dehydrogenase NADP, mitochondrial precursor
[Coccidioides immitis RS]
gb|EAS28927.1| isocitrate dehydrogenase NADP, mitochondrial precursor
[Coccidioides immitis RS]
Length = 509
Score = 694 bits (1793), Expect = 0.0, Method: Composition-based stats.
Identities = 265/409 (64%), Positives = 328/409 (80%), Gaps = 2/409 (0%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
KIKV +P+VE+DGDE TR+IW+ IK+K I PYLDVDLKYYDL ++ RD+T+D+VT D++
Sbjct: 102 KIKVKNPVVELDGDEMTRIIWQDIKDKFIYPYLDVDLKYYDLGLEYRDQTDDKVTVDAAE 161
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRLVP
Sbjct: 162 AIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRLVP 221
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W+KPIIIGRHAFGDQYRATD + GKL L ++ +G E + VY+F + GIA
Sbjct: 222 GWKKPIIIGRHAFGDQYRATDRLVPGPGKLELVYTPTNG-EPERITVYDF-QGAGIAQVQ 279
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT+DSI+GFA ASF+LAL + LP++ +TKNTILK YD +FK IF+ +++ EYK+ F+A
Sbjct: 280 YNTDDSIRGFAHASFKLALLKGLPMYMSTKNTILKKYDGRFKDIFEEVYEAEYKKAFEAK 339
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
I YEHRLIDDMVAQM+K GG +IAMKNYDGDVQSDIVAQGFGSLGLMTS L TPDG
Sbjct: 340 GIWYEHRLIDDMVAQMIKGDGGCVIAMKNYDGDVQSDIVAQGFGSLGLMTSTLTTPDGSA 399
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +I+RG+LD T DV+ F LE+A
Sbjct: 400 FESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIRRGQLDETPDVVTFAEQLERA 459
Query: 363 TLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
++ V G MTKDLAL GK R ++VTT E++D V +RL++ + ++
Sbjct: 460 CIEVVDEEGIMTKDLALSCGKKERDAWVTTREYMDAVERRLRSNLANAK 508
>ref|ZP_02188085.1| Isocitrate dehydrogenase [alpha proteobacterium BAL199]
gb|EDP65245.1| Isocitrate dehydrogenase [alpha proteobacterium BAL199]
Length = 404
Score = 694 bits (1792), Expect = 0.0, Method: Composition-based stats.
Identities = 251/407 (61%), Positives = 314/407 (77%), Gaps = 4/407 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +PIVE+DGDE TR+IW++IK+KLILPYLDVDLKYYDL ++ RD+T+DQ+T DS
Sbjct: 1 MAKIKVANPIVELDGDEMTRIIWQMIKDKLILPYLDVDLKYYDLGMEARDKTDDQITVDS 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A ++GV VKCATITPDE R+ EF LK+MW+SPNGTIRNILGGTVFR+PI+ +PRL
Sbjct: 61 ANAIKEFGVGVKCATITPDEDRVAEFGLKKMWRSPNGTIRNILGGTVFRQPILCKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W +PI+IGRHAFGDQYRATD + GKL L F +DG E + V++FP GG+AM
Sbjct: 121 VPGWTQPIVIGRHAFGDQYRATDFVVPGKGKLTLTFQPEDGGEPMTFNVFDFP-GGGVAM 179
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI GFA+A F L P++ +TKNTILK YD +FK +F +FD E+ KF+
Sbjct: 180 AMYNLDESIIGFARACFNYGLDLGWPVYLSTKNTILKAYDGRFKDLFQEVFDAEFASKFK 239
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVA LK G F+ A KNYDGDVQSD VAQGFGSLGLMTS+L+TPDG
Sbjct: 240 AKGIIYEHRLIDDMVASALKWSGNFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDG 299
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRHFR+HQ+G+ETSTN IASIFAWTR + R K D T +V +F LE
Sbjct: 300 KTVEAEAAHGTVTRHFRQHQQGKETSTNPIASIFAWTRGLSFRAKFDETPEVGRFAETLE 359
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
K +DTV+ G MTKDLAL++ ++TT++F+ ++ + LQ M
Sbjct: 360 KVCVDTVE-DGHMTKDLALLISPDQ--PWLTTQQFLGKLDENLQKAM 403
>ref|NP_001014183.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Rattus
norvegicus]
sp|P56574|IDHP_RAT Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAH76398.1| Similar to NADP+-specific isocitrate dehydrogenase [Rattus
norvegicus]
gb|EDM08608.1| similar to NADP+-specific isocitrate dehydrogenase, isoform CRA_b
[Rattus norvegicus]
Length = 452
Score = 694 bits (1791), Expect = 0.0, Method: Composition-based stats.
Identities = 252/412 (61%), Positives = 310/412 (75%), Gaps = 6/412 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 43 RIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD + +AG +L F+ DG + +VY FP +GG+ M M
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVVDRAGMFKLVFTPKDGSGAKEWEVYNFP-AGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ ++++K PL+ +TKNTI+K YD +FK IF +FDK YK F
Sbjct: 222 YNTDESISGFAHSCFQYSIQKKWPLYLSTKNTIMKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
+ TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 402 CVQTVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ 452
>emb|CAG38738.1| IDH1 [Homo sapiens]
Length = 414
Score = 694 bits (1791), Expect = 0.0, Method: Composition-based stats.
Identities = 243/414 (58%), Positives = 311/414 (75%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A K+ V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ +++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVSIETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>ref|ZP_00056387.1| COG0538: Isocitrate dehydrogenases [Magnetospirillum
magnetotacticum MS-1]
Length = 405
Score = 693 bits (1790), Expect = 0.0, Method: Composition-based stats.
Identities = 251/408 (61%), Positives = 318/408 (77%), Gaps = 5/408 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M KIKV +PIVE+DGDE TR+IWK IK+KLILPYLDVDLKYYDL I+ RD+T+D+VT ++
Sbjct: 1 MKKIKVANPIVELDGDEMTRIIWKFIKDKLILPYLDVDLKYYDLGIEYRDKTDDKVTVEA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
S A KYGV VKCATITPDEAR+KEFNLK+MWKSPNGTIRNIL GTVFREPII +PRL
Sbjct: 61 SEAIKKYGVGVKCATITPDEARVKEFNLKKMWKSPNGTIRNILDGTVFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPI+IGRHAFGDQY+ATD + GKL ++F +G E I+ +V++FP G+AM
Sbjct: 121 VPGWTKPIVIGRHAFGDQYKATDFTVPGPGKLTIKFVGTNG-ETIEHEVFDFP-GAGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N ++SI GFA+A ++K P++ +TKNTILK YD +FK IF +++KE+K +
Sbjct: 179 GMYNLDESIYGFARACLNYGRQKKWPVYLSTKNTILKAYDGRFKDIFQEVYEKEFKADYD 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
L ITYEHRLIDDMVA LK G F+ A KNYDGDVQSD VAQGFGSLGLMTS+L++PDG
Sbjct: 239 KLGITYEHRLIDDMVASALKWSGEFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMSPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
K E+EAAHGTVTRH+R+HQ+G+ETSTN IASIFAWTR + R + DNT +V F LE
Sbjct: 299 KVVEAEAAHGTVTRHYREHQKGKETSTNPIASIFAWTRGLFYRAQFDNTPEVANFAQALE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMML 408
+ ++TV+ G MTKDLA+++G S++TT++F+D++ + L+ M
Sbjct: 359 EVCVETVE-SGFMTKDLAILIGPGQ--SWLTTQQFLDKLDENLKKRMA 403
>ref|NP_005887.2| isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens]
sp|O75874|IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
pdb|1T09|A Chain A, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex Nadp
pdb|1T09|B Chain B, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex Nadp
pdb|1T0L|A Chain A, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|B Chain B, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|C Chain C, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|D Chain D, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
gb|AAD29284.1|AF113917_1 NADP+-dependent isocitrate dehydrogenase [Homo sapiens]
gb|AAH12846.1| IDH1 protein [Homo sapiens]
emb|CAG46496.1| IDH1 [Homo sapiens]
gb|AAX93221.1| unknown [Homo sapiens]
gb|EAW70439.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|EAW70441.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|EAW70442.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|ABM82361.1| isocitrate dehydrogenase 1 (NADP+), soluble [synthetic construct]
gb|ABW03396.1| isocitrate dehydrogenase 1 (NADP+), soluble [synthetic construct]
Length = 414
Score = 693 bits (1789), Expect = 0.0, Method: Composition-based stats.
Identities = 243/414 (58%), Positives = 311/414 (75%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A K+ V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ +++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVSIETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>ref|XP_510589.2| PREDICTED: isocitrate dehydrogenase 2 (NADP+), mitochondrial
isoform 4 [Pan troglodytes]
Length = 452
Score = 693 bits (1789), Expect = 0.0, Method: Composition-based stats.
Identities = 251/412 (60%), Positives = 310/412 (75%), Gaps = 6/412 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++D+ LKY+DL + RD+T+DQVT DS+
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD +AG ++ F+ DG + +VY FP +GG+ M M
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 402 CVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452
>sp|Q5R9C5|IDHC_PONPY Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
Length = 414
Score = 693 bits (1789), Expect = 0.0, Method: Composition-based stats.
Identities = 244/414 (58%), Positives = 311/414 (75%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ +++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVSVETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD34457.1|AF136009_1 cytosolic NADP+-dependent isocitrate dehydrogenase [Bos taurus]
Length = 414
Score = 693 bits (1789), Expect = 0.0, Method: Composition-based stats.
Identities = 242/414 (58%), Positives = 306/414 (73%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS+ +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG V+ F +SGG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ET TN IASIFAWTR + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETLTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + LQ + +
Sbjct: 361 EVCIETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAK 413
>ref|YP_290624.1| isocitrate dehydrogenase [Thermobifida fusca YX]
gb|AAZ56601.1| isocitrate dehydrogenase (NADP) [Thermobifida fusca YX]
Length = 406
Score = 693 bits (1788), Expect = 0.0, Method: Composition-based stats.
Identities = 246/409 (60%), Positives = 317/409 (77%), Gaps = 3/409 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW IKE+LILPYLD+DLKYYDL I+ERDRT DQVT D+
Sbjct: 1 MAKIKVENPVVELDGDEMTRIIWSFIKERLILPYLDIDLKYYDLGIEERDRTEDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
++A KYGV VKCATITPDEAR++EF LK+MW+SPNGTIRNILGG VFREPII +PRL
Sbjct: 61 AHAIKKYGVGVKCATITPDEARVEEFGLKKMWRSPNGTIRNILGGVVFREPIICSNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPIIIGRHA GDQY+A+D K+ G + + ++ ++G E I+++V +FP+ GG+A+
Sbjct: 121 VPGWTKPIIIGRHAHGDQYKASDFKVPGPGTVTITYTPENGGEPIEMEVAKFPEGGGVAL 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N SI+ FA+A F L R P++ +TKNTILK YD FK +F +++ E+KEKF+
Sbjct: 181 GMYNFRKSIEDFARACFNYGLDRNYPVYLSTKNTILKAYDGMFKDVFAEIYENEFKEKFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
+TYEHRLIDDMVA LK +GG++ A KNYDGDVQSD VAQGFGSLGLMTS+L T DG
Sbjct: 241 KAGLTYEHRLIDDMVAAALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLRTSDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+ E+EAAHGTVTRH+R+HQ+G+ TSTN IASIFAWTR + RGKLDNT VI+F LE
Sbjct: 301 RVVEAEAAHGTVTRHYRQHQQGKPTSTNPIASIFAWTRGLEHRGKLDNTPAVIEFARTLE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
+ TV+ G+MTKDLA+++G ++TTE+F+ + + LQ + +
Sbjct: 361 DVVIKTVE-SGQMTKDLAILIGPDQE--WLTTEQFLAVLDENLQKRLAA 406
>ref|XP_850187.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 2 [Canis familiaris]
ref|XP_536047.2| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 1 [Canis familiaris]
Length = 414
Score = 692 bits (1787), Expect = 0.0, Method: Composition-based stats.
Identities = 242/414 (58%), Positives = 307/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS+ +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG E + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + L + +
Sbjct: 361 EVCVETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAK 413
>dbj|BAC39792.1| unnamed protein product [Mus musculus]
Length = 422
Score = 692 bits (1787), Expect = 0.0, Method: Composition-based stats.
Identities = 243/414 (58%), Positives = 310/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS+ +VEM GDE TR+IW+LIKEKLILPY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSRKIQGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V++F + GG+AM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGTQKVTYMVHDFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKKYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 AQKICYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAW+R + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 DVCIETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAQ 413
>ref|XP_001141655.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 1
[Pan troglodytes]
ref|XP_001141734.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 2
[Pan troglodytes]
ref|XP_001141810.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 3
[Pan troglodytes]
ref|XP_001141879.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 4
[Pan troglodytes]
ref|XP_001141947.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 5
[Pan troglodytes]
ref|XP_001142041.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 6
[Pan troglodytes]
ref|XP_001142113.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 7
[Pan troglodytes]
ref|XP_001142197.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 8
[Pan troglodytes]
Length = 414
Score = 692 bits (1787), Expect = 0.0, Method: Composition-based stats.
Identities = 244/414 (58%), Positives = 310/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKRYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLG---KTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ +++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVSIETIE-AGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>ref|XP_001095686.1| PREDICTED: isocitrate dehydrogenase 2 (NADP+), mitochondrial
[Macaca mulatta]
sp|Q4R502|IDHP_MACFA Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
dbj|BAE01823.1| unnamed protein product [Macaca fascicularis]
Length = 452
Score = 692 bits (1787), Expect = 0.0, Method: Composition-based stats.
Identities = 251/412 (60%), Positives = 310/412 (75%), Gaps = 6/412 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV P+VEMDGDE TR+IW+ IKEKLILP++D+ LKY+DL + RD+T+DQVT DS+
Sbjct: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W KPI IGRHA GDQY+ATD +AG ++ F+ DG + +VY FP +GG+ M M
Sbjct: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKV 401
Query: 363 TLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 402 CVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452
>gb|AAC64182.1| NADP-dependent isocitrate dehydrogenase [Glycine max]
Length = 416
Score = 692 bits (1787), Expect = 0.0, Method: Composition-based stats.
Identities = 262/413 (63%), Positives = 323/413 (78%), Gaps = 3/413 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
KI+V +PIVEMDGDE TRVIWKLIK+KLI PYL++D+KY+DL + RD TND+VT +S+
Sbjct: 4 QKIRVGNPIVEMDGDEMTRVIWKLIKDKLIFPYLELDIKYFDLGLPHRDATNDRVTIESA 63
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
ATLKY VA+KCATITPDEAR+KEFNLK+MW+SPNGTIRNIL GTVFREPII IPRLV
Sbjct: 64 EATLKYNVAIKCATITPDEARVKEFNLKQMWRSPNGTIRNILNGTVFREPIICKNIPRLV 123
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
W KPI IGRHAFGDQYRATD IK GKL+L F+ + +L+VY F +GGIA++
Sbjct: 124 SGWTKPICIGRHAFGDQYRATDTVIKGPGKLKLVFAPSGNEGIKELEVYNFTGAGGIALS 183
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI+ FA+AS A ++K PL+ +TKNTILK YD +FK IF +FD ++ KF+A
Sbjct: 184 MYNTDESIRAFAEASMNFAYQKKWPLYLSTKNTILKKYDGRFKDIFQEVFDTQWNHKFKA 243
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVA LKS GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGK
Sbjct: 244 AGIWYEHRLIDDMVAYALKSDGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGK 303
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+R + R KLD ++ F LE
Sbjct: 304 TIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRPKLDGNARLLDFTEKLEA 363
Query: 362 ATLDTVQVGGKMTKDLALMLG--KTNRSSYVTTEEFIDEVAKRLQNMMLSSNE 412
A + TV++ GKMTKDLAL++ K +RS Y+ TEEFID VA+ L+ + S ++
Sbjct: 364 ACIGTVEL-GKMTKDLALLVHGPKVSRSQYLNTEEFIDAVAEELRTRLSSQSK 415
Searching..................................................done
Results from round 3
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
ref|XP_536192.2| PREDICTED: similar to isocitrate dehydroge... 710 0.0
ref|XP_001903959.1| unnamed protein product [Podospora anse... 710 0.0
ref|NP_786984.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 710 0.0
sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitoc... 709 0.0
ref|NP_001026770.1| hypothetical protein LOC431056 [Gallus ... 709 0.0
sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitoc... 708 0.0
ref|XP_001240510.1| isocitrate dehydrogenase NADP, mitochon... 708 0.0
ref|NP_766599.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 708 0.0
gb|ACO14046.1| Isocitrate dehydrogenase, mitochondrial prec... 708 0.0
ref|NP_539708.1| isocitrate dehydrogenase [Brucella meliten... 707 0.0
ref|XP_955850.1| hypothetical protein NCU03857 [Neurospora ... 707 0.0
ref|XP_001226620.1| conserved hypothetical protein [Chaetom... 707 0.0
ref|NP_955858.1| isocitrate dehydrogenase 2 (NADP+), mitoch... 707 0.0
ref|NP_001014183.1| isocitrate dehydrogenase 2 (NADP+), mit... 706 0.0
ref|XP_754749.1| isocitrate dehydrogenase Idp1 [Aspergillus... 706 0.0
gb|EDP52872.1| isocitrate dehydrogenase Idp1, putative [Asp... 706 0.0
ref|NP_698203.1| isocitrate dehydrogenase [Brucella suis 13... 706 0.0
ref|XP_001107627.1| PREDICTED: isocitrate dehydrogenase 1 (... 706 0.0
ref|XP_510589.2| PREDICTED: isocitrate dehydrogenase 2 (NAD... 706 0.0
sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytopl... 705 0.0
ref|XP_001369305.1| PREDICTED: hypothetical protein [Monode... 705 0.0
ref|XP_001095686.1| PREDICTED: isocitrate dehydrogenase 2 (... 705 0.0
emb|CAM77136.1| Isocitrate/isopropylmalate dehydrogenase [M... 704 0.0
ref|NP_113698.1| isocitrate dehydrogenase 1 (NADP+), solubl... 704 0.0
ref|XP_421965.2| PREDICTED: similar to cytosolic NADP-depen... 704 0.0
ref|NP_001009276.1| cytosolic NADP-isocitrate dehydrogenase... 704 0.0
sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytopl... 704 0.0
ref|NP_851355.2| isocitrate dehydrogenase 1 (NADP+), solubl... 704 0.0
ref|NP_002159.2| isocitrate dehydrogenase 2 (NADP+), mitoch... 704 0.0
gb|ABE98244.1| mitochondrial isocitrate dehydrogenase 2-lik... 704 0.0
ref|XP_001778805.1| predicted protein [Physcomitrella paten... 703 0.0
emb|CAG38738.1| IDH1 [Homo sapiens] 703 0.0
gb|ABU41004.1| isocitrate dehydrogenase 1 [Anser anser] 703 0.0
ref|XP_850187.1| PREDICTED: similar to Isocitrate dehydroge... 703 0.0
ref|NP_005887.2| isocitrate dehydrogenase 1 (NADP+), solubl... 703 0.0
emb|CAA49208.1| isocitrate dehydrogenase (NADP+) [Homo sapi... 703 0.0
pdb|1LWD|A Chain A, Crystal Structure Of Nadp-Dependent Iso... 703 0.0
ref|NP_001088022.1| hypothetical protein LOC494713 [Xenopus... 702 0.0
sp|P33198|IDHP_PIG Isocitrate dehydrogenase [NADP], mitocho... 702 0.0
dbj|BAD96636.1| isocitrate dehydrogenase 2 (NADP+), mitocho... 702 0.0
gb|EEJ98364.1| isocitrate dehydrogenase (NADP) [Thermomonos... 702 0.0
gb|AAC64182.1| NADP-dependent isocitrate dehydrogenase [Gly... 702 0.0
sp|Q5R9C5|IDHC_PONPY Isocitrate dehydrogenase [NADP] cytopl... 702 0.0
gb|AAB39248.1| NADP-isocitrate dehydrogenase [Eucalyptus gl... 702 0.0
ref|XP_001141655.1| PREDICTED: isocitrate dehydrogenase 1 (... 702 0.0
sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytopl... 701 0.0
emb|CAA53300.1| isocitrate dehydrogenase (NADP+) [Solanum t... 701 0.0
ref|XP_001505172.1| PREDICTED: similar to Isocitrate dehydr... 701 0.0
gb|AAH93020.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 701 0.0
gb|EAX02083.1| isocitrate dehydrogenase 2 (NADP+), mitochon... 701 0.0
dbj|BAC39792.1| unnamed protein product [Mus musculus] 700 0.0
ref|XP_001168316.1| PREDICTED: isocitrate dehydrogenase 2 (... 700 0.0
ref|NP_970434.1| isocitrate dehydrogenase [Bdellovibrio bac... 700 0.0
emb|CAD97653.1| hypothetical protein [Homo sapiens] >gi|117... 700 0.0
ref|XP_001593497.1| hypothetical protein SS1G_04924 [Sclero... 699 0.0
ref|YP_290624.1| isocitrate dehydrogenase [Thermobifida fus... 699 0.0
sp|O88844|IDHC_MOUSE Isocitrate dehydrogenase [NADP] cytopl... 699 0.0
emb|CAH89719.1| hypothetical protein [Pongo abelii] 699 0.0
ref|NP_034627.3| isocitrate dehydrogenase 1 (NADP+), solubl... 699 0.0
ref|NP_001080321.1| hypothetical protein LOC380013 [Xenopus... 699 0.0
emb|CAB66637.1| hypothetical protein [Homo sapiens] >gi|117... 699 0.0
gb|AAK76730.1| mitochondrial NADP-dependent isocitrate dehy... 698 0.0
emb|CAH91635.1| hypothetical protein [Pongo abelii] 698 0.0
sp|Q40345|IDHP_MEDSA Isocitrate dehydrogenase [NADP], chlor... 698 0.0
dbj|BAE39644.1| unnamed protein product [Mus musculus] 698 0.0
gb|AAH88986.1| Isocitrate dehydrogenase 1 (NADP+), soluble ... 698 0.0
gb|AAA33978.1| NADPH-specific isocitrate dehydrogenase 698 0.0
ref|YP_001370537.1| isocitrate dehydrogenase, NADP-dependen... 697 0.0
sp|P79089|IDHP_ASPNG Isocitrate dehydrogenase [NADP], mitoc... 697 0.0
ref|XP_001168291.1| PREDICTED: isocitrate dehydrogenase 2 (... 697 0.0
sp|P50218|IDHC_TOBAC Isocitrate dehydrogenase [NADP] (Oxalo... 697 0.0
pir||S33612 isocitrate dehydrogenase (NADP) (EC 1.1.1.42) -... 697 0.0
gb|AAD02918.1| NADP-dependent isocitrate dehydrogenase [Hom... 697 0.0
ref|ZP_02188085.1| Isocitrate dehydrogenase [alpha proteoba... 696 0.0
emb|CAG02362.1| unnamed protein product [Tetraodon nigrovir... 696 0.0
ref|ZP_00056387.1| COG0538: Isocitrate dehydrogenases [Magn... 696 0.0
pdb|2CMJ|A Chain A, Crystal Structure Of Mouse Cytosolic Is... 696 0.0
ref|XP_001511049.1| PREDICTED: similar to cytosolic NADP-de... 696 0.0
dbj|BAA34113.1| NADP specific isocitrate dehydrogenase [Dau... 696 0.0
ref|NP_001004799.1| MGC69505 protein [Xenopus tropicalis] >... 695 0.0
ref|YP_002826161.1| NADP isocitrate dehydrogenase [Rhizobiu... 695 0.0
sp|P50217|IDHC_SOLTU Isocitrate dehydrogenase [NADP] (Oxalo... 695 0.0
emb|CAG38553.1| IDH1 [Homo sapiens] 694 0.0
dbj|BAC77065.1| NADP-specific isocitrate dehydrogenase [Lup... 694 0.0
ref|NP_001056381.1| Os05g0573200 [Oryza sativa (japonica cu... 694 0.0
emb|CAG13105.1| unnamed protein product [Tetraodon nigrovir... 694 0.0
dbj|BAA34112.1| NADP specific isocitrate dehydrogenase [Dau... 694 0.0
ref|YP_419971.1| isocitrate dehydrogenase [Magnetospirillum... 694 0.0
ref|YP_706173.1| isocitrate dehydrogenase [Rhodococcus sp. ... 693 0.0
ref|YP_002761841.1| NADP-dependent isocitrate dehydrogenase... 693 0.0
ref|ZP_03891012.1| isocitrate dehydrogenase (NADP) [Geoderm... 693 0.0
dbj|BAC77063.1| NADP-specific isocitrate dehydrogenase [Lup... 693 0.0
ref|NP_385898.1| isocitrate dehydrogenase [Sinorhizobium me... 693 0.0
ref|NP_001043749.1| Os01g0654500 [Oryza sativa (japonica cu... 693 0.0
emb|CAA73139.1| isocitrate dehydrogenase (NADP+) [Apium gra... 692 0.0
gb|AAD51361.1|AF176669_1 NADP-isocitrate dehydrogenase [Cit... 692 0.0
ref|YP_425448.1| isocitrate dehydrogenase [Rhodospirillum r... 692 0.0
dbj|BAE48792.1| NADP-isocitrate dehydrogenase [Codonopsis l... 692 0.0
gb|ABA18651.1| cytosolic NADP+-isocitrate dehydrogenase [Po... 692 0.0
ref|XP_001365492.1| PREDICTED: similar to cytosolic NADP-de... 692 0.0
ref|XP_390523.1| hypothetical protein FG10347.1 [Gibberella... 692 0.0
sp|Q06197|IDHC_SOYBN Isocitrate dehydrogenase [NADP] (Oxalo... 692 0.0
ref|ZP_03869030.1| isocitrate dehydrogenase (NADP) [Jonesia... 691 0.0
gb|AAF73472.1|AF268076_1 NADP-dependent isocitrate dehydrog... 691 0.0
ref|XP_860821.1| PREDICTED: similar to Isocitrate dehydroge... 691 0.0
ref|NP_101923.1| isocitrate dehydrogenase [Mesorhizobium lo... 691 0.0
ref|YP_001327198.1| isocitrate dehydrogenase [Sinorhizobium... 691 0.0
ref|XP_001168261.1| PREDICTED: isocitrate dehydrogenase 2 (... 691 0.0
gb|AAL11503.1|AF367443_1 NADP-dependent isocitrate dehydrog... 691 0.0
ref|YP_673828.1| isocitrate dehydrogenase [Mesorhizobium sp... 690 0.0
gb|AAC52473.1| isocitrate dehydrogenase 690 0.0
prf||2211361A isocitrate dehydrogenase 689 0.0
ref|XP_451683.1| unnamed protein product [Kluyveromyces lac... 689 0.0
ref|XP_001400371.1| precursor of mitochondrial isocitrate d... 689 0.0
ref|XP_001778590.1| predicted protein [Physcomitrella paten... 689 0.0
gb|AAK76731.1| peroxisomal NADP-dependent isocitrate dehydr... 689 0.0
emb|CAD24779.1| isocitrate dehydrogenase [Cucumis sativus] 689 0.0
ref|ZP_01885694.1| isocitrate dehydrogenase [Pedobacter sp.... 689 0.0
ref|ZP_02124492.1| Isocitrate dehydrogenase (NADP(+)) [Meth... 689 0.0
ref|ZP_02166681.1| isocitrate dehydrogenase [Hoeflea photot... 688 0.0
ref|XP_367343.2| hypothetical protein MGG_07268 [Magnaporth... 688 0.0
dbj|BAC77064.1| NADP-specific isocitrate dehydrogenase [Lup... 688 0.0
ref|XP_860853.1| PREDICTED: similar to Isocitrate dehydroge... 688 0.0
ref|YP_872148.1| isocitrate dehydrogenase [Acidothermus cel... 688 0.0
gb|ABK24873.1| unknown [Picea sitchensis] 688 0.0
gb|AAR05796.1| NADP+-isocitrate dehydrogenase [Pinus pinaster] 688 0.0
ref|NP_421325.1| isocitrate dehydrogenase [Caulobacter cres... 687 0.0
gb|AAT06312.1| isocitrate dehydrogenase [Rhizobium legumino... 687 0.0
ref|XP_504978.1| hypothetical protein [Yarrowia lipolytica]... 687 0.0
gb|AAS49171.1| NADP-dependent isocitrate dehydrogenase [Pis... 687 0.0
ref|YP_768215.1| isocitrate dehydrogenase [Rhizobium legumi... 687 0.0
ref|YP_117132.1| isocitrate dehydrogenase [Nocardia farcini... 687 0.0
ref|ZP_02295934.1| isocitrate dehydrogenase, NADP-dependent... 687 0.0
ref|NP_958907.1| isocitrate dehydrogenase 1 (NADP+), solubl... 687 0.0
ref|YP_002783489.1| isocitrate dehydrogenase [Rhodococcus o... 687 0.0
ref|NP_354851.2| isocitrate dehydrogenase [Agrobacterium tu... 686 0.0
ref|YP_001524781.1| NADP-dependent isocitrate dehydrogenase... 686 0.0
ref|YP_002765452.1| NADP-dependent isocitrate dehydrogenase... 686 0.0
ref|XP_001528456.1| isocitrate dehydrogenase, mitochondrial... 686 0.0
ref|ZP_02858718.1| isocitrate dehydrogenase, NADP-dependent... 686 0.0
emb|CAQ15240.1| isocitrate dehydrogenase 1 (NADP+), soluble... 686 0.0
gb|EDT29808.1| isocitrate dehydrogenase, NADP-dependent [Ol... 686 0.0
ref|XP_001384028.1| Isocitrate dehydrogenase [NADP], mitoch... 686 0.0
ref|XP_001263574.1| isocitrate dehydrogenase Idp1, putative... 686 0.0
ref|YP_001609735.1| NADP-dependent isocitrate dehydrogenase... 686 0.0
ref|XP_660603.1| IDHP_ASPNG ISOCITRATE DEHYDROGENASE [NADP]... 685 0.0
ref|YP_001413846.1| isocitrate dehydrogenase, NADP-dependen... 685 0.0
ref|XP_001818331.1| hypothetical protein [Aspergillus oryza... 684 0.0
ref|YP_001685152.1| isocitrate dehydrogenase, NADP-dependen... 684 0.0
emb|CAN72808.1| hypothetical protein [Vitis vinifera] >gi|1... 684 0.0
ref|XP_001633903.1| predicted protein [Nematostella vectens... 684 0.0
ref|YP_001849499.1| isocitrate dehydrogenase [NADP] Icd1 [M... 684 0.0
gb|AAV33246.1| isocitrate dehydrogenase [Toxoplasma gondii] 684 0.0
ref|YP_677841.1| isocitrate dehydrogenase [Cytophaga hutchi... 684 0.0
emb|CAG02627.1| unnamed protein product [Tetraodon nigrovir... 684 0.0
ref|XP_001698704.1| isocitrate dehydrogenase, NADP-dependen... 684 0.0
emb|CAA65503.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 683 0.0
ref|NP_196963.2| isocitrate dehydrogenase, putative / NADP+... 683 0.0
ref|XP_710919.1| NADP-specific isocitrate dehydrogenase [Ca... 682 0.0
ref|YP_001623415.1| isocitrate dehydrogenase (NADP) [Reniba... 682 0.0
ref|ZP_00952302.1| isocitrate dehydrogenase [Oceanicaulis a... 682 0.0
ref|YP_001769504.1| isocitrate dehydrogenase, NADP-dependen... 682 0.0
gb|EAY58582.1| isocitrate dehydrogenase [NADP] icd1 [Mycoba... 682 0.0
emb|CAA65504.1| isocitrate dehydrogenase (NADP+) [Nicotiana... 682 0.0
gb|EDU40785.1| isocitrate dehydrogenase, mitochondrial prec... 682 0.0
ref|YP_001108727.1| isocitrate dehydrogenase [Saccharopolys... 682 0.0
ref|NP_217856.1| isocitrate dehydrogenase [Mycobacterium tu... 682 0.0
gb|EAY99113.1| hypothetical protein OsI_020346 [Oryza sativ... 681 0.0
ref|NP_175836.1| ICDH; isocitrate dehydrogenase (NADP+) [Ar... 681 0.0
ref|XP_001841910.1| isocitrate dehydrogenase cytoplasmic [C... 681 0.0
emb|CAO64975.1| unnamed protein product [Vitis vinifera] 681 0.0
ref|YP_979491.1| isocitrate dehydrogenase [Mycobacterium bo... 681 0.0
ref|YP_001538953.1| isocitrate dehydrogenase, NADP-dependen... 681 0.0
ref|XP_001688948.1| AGAP006660-PA [Anopheles gambiae str. P... 681 0.0
ref|ZP_01228834.1| NADP dependent isocitrate dehydrogenase ... 680 0.0
ref|ZP_03819206.1| isocitrate dehydrogenase (NADP) [Actinos... 680 0.0
ref|ZP_01862723.1| isocitrate dehydrogenase [Erythrobacter ... 679 0.0
ref|YP_001160602.1| isocitrate dehydrogenase [Salinispora t... 679 0.0
ref|ZP_01040029.1| isocitrate dehydrogenase [Erythrobacter ... 679 0.0
ref|YP_756242.1| isocitrate dehydrogenase [Maricaulis maris... 679 0.0
ref|YP_032403.1| isocitrate dehydrogenase [Bartonella quint... 679 0.0
ref|YP_496560.1| isocitrate dehydrogenase [Novosphingobium ... 679 0.0
ref|YP_062774.1| isocitrate dehydrogenase [Leifsonia xyli s... 679 0.0
ref|NP_176768.1| isocitrate dehydrogenase, putative / NADP+... 678 0.0
ref|YP_001296741.1| isocitrate dehydrogenase [Flavobacteriu... 678 0.0
ref|ZP_01546031.1| isocitrate dehydrogenase [Stappia aggreg... 678 0.0
ref|YP_001419447.1| isocitrate dehydrogenase, NADP-dependen... 678 0.0
ref|ZP_02955422.1| isocitrate dehydrogenase, NADP-dependent... 677 0.0
ref|ZP_03813993.1| isocitrate dehydrogenase (NADP) [Beutenb... 677 0.0
ref|XP_970446.1| PREDICTED: similar to isocitrate dehydroge... 677 0.0
ref|ZP_01440188.1| Isocitrate/isopropylmalate dehydrogenase... 677 0.0
ref|XP_001837820.1| hypothetical protein CC1G_11465 [Coprin... 677 0.0
ref|ZP_01303522.1| isocitrate dehydrogenase, NADP-dependent... 677 0.0
gb|AAM13090.1| similar to NADP-specific isocitrate dehydrog... 677 0.0
ref|NP_772387.1| isocitrate dehydrogenase [Bradyrhizobium j... 677 0.0
ref|YP_001832264.1| isocitrate dehydrogenase, NADP-dependen... 677 0.0
emb|CAD24782.1| isocitrate dehydrogenase [Arabidopsis thali... 676 0.0
ref|XP_459772.1| hypothetical protein DEHA0E11286g [Debaryo... 676 0.0
ref|YP_033790.1| isocitrate dehydrogenase [Bartonella hense... 676 0.0
ref|YP_682929.1| isocitrate dehydrogenase [Roseobacter deni... 676 0.0
ref|YP_001233708.1| isocitrate dehydrogenase [Acidiphilium ... 676 0.0
ref|XP_001484278.1| isocitrate dehydrogenase, mitochondrial... 676 0.0
gb|AAM65674.1| isocitrate dehydrogenase, putative [Arabidop... 676 0.0
ref|YP_001363715.1| isocitrate dehydrogenase, NADP-dependen... 676 0.0
ref|NP_001042583.1| Os01g0248400 [Oryza sativa (japonica cu... 675 0.0
ref|YP_001709366.1| isocitrate dehydrogenase [Clavibacter m... 675 0.0
ref|NP_984921.1| AER061Cp [Ashbya gossypii ATCC 10895] >gi|... 675 0.0
ref|YP_001223282.1| isocitrate dehydrogenase [Clavibacter m... 675 0.0
ref|XP_968850.1| PREDICTED: similar to CG7176-PC, isoform C... 675 0.0
ref|XP_001650675.1| nadp-specific isocitrate dehydrogenase ... 674 0.0
ref|ZP_03896321.1| isocitrate dehydrogenase (NADP) [Dyadoba... 674 0.0
ref|ZP_03922528.1| isocitrate dehydrogenase [Mobiluncus cur... 674 0.0
gb|EDN62799.1| NADP-dependent isocitrate dehydrogenase [Sac... 674 0.0
ref|NP_014389.1| Peroxisomal NADP-dependent isocitrate dehy... 674 0.0
ref|XP_001176537.1| PREDICTED: similar to Isocitrate dehydr... 674 0.0
sp|O13285|IDH1_CANTR Isocitrate dehydrogenase [NADP], mitoc... 674 0.0
ref|YP_001758392.1| isocitrate dehydrogenase, NADP-dependen... 674 0.0
emb|CAB87626.1| isocitrate dehydrogenase-like protein [Arab... 674 0.0
ref|YP_001833636.1| isocitrate dehydrogenase, NADP-dependen... 673 0.0
ref|YP_989041.1| isocitrate dehydrogenase [Bartonella bacil... 673 0.0
ref|XP_001527573.1| isocitrate dehydrogenase peroxisomal [L... 673 0.0
ref|NP_010217.1| Mitochondrial NADP-specific isocitrate deh... 673 0.0
ref|XP_713421.1| cytosolic NADP-specific isocitrate dehydro... 673 0.0
ref|XP_312860.4| AGAP003168-PA [Anopheles gambiae str. PEST... 672 0.0
ref|YP_617009.1| isocitrate dehydrogenase [Sphingopyxis ala... 672 0.0
ref|YP_458429.1| isocitrate dehydrogenase [Erythrobacter li... 672 0.0
ref|XP_001270886.1| isocitrate dehydrogenase Idp1, putative... 672 0.0
ref|ZP_00954676.1| isocitrate dehydrogenase [Sulfitobacter ... 672 0.0
ref|XP_001878769.1| predicted protein [Laccaria bicolor S23... 672 0.0
ref|YP_001601185.1| Isocitrate dehydrogenase [Gluconacetoba... 671 0.0
sp|P50215|IDH_SPHYA Isocitrate dehydrogenase [NADP] (Oxalos... 671 0.0
ref|ZP_00964081.1| isocitrate dehydrogenase [Sulfitobacter ... 671 0.0
emb|CAA63220.1| isocitrate dehydrogenase (NAD+) [Solanum tu... 671 0.0
ref|NP_949171.1| isocitrate dehydrogenase [Rhodopseudomonas... 671 0.0
ref|ZP_02302766.1| isocitrate dehydrogenase, NADP-dependent... 670 0.0
gb|ACO14957.1| Isocitrate dehydrogenase cytoplasmic [Caligu... 670 0.0
ref|ZP_02981592.1| isocitrate dehydrogenase, NADP-dependent... 670 0.0
ref|NP_962389.1| isocitrate dehydrogenase [Mycobacterium av... 669 0.0
ref|XP_445447.1| unnamed protein product [Candida glabrata]... 669 0.0
ref|YP_487337.1| isocitrate dehydrogenase [Rhodopseudomonas... 669 0.0
ref|NP_001053269.1| Os04g0508200 [Oryza sativa (japonica cu... 669 0.0
ref|YP_001204807.1| isocitrate dehydrogenase [Bradyrhizobiu... 669 0.0
ref|YP_909639.1| isocitrate dehydrogenase [Bifidobacterium ... 669 0.0
ref|ZP_00206729.1| COG0538: Isocitrate dehydrogenases [Bifi... 669 0.0
ref|XP_001608101.1| PREDICTED: similar to isocitrate dehydr... 668 0.0
ref|XP_001646579.1| hypothetical protein Kpol_1055p78 [Vand... 668 0.0
ref|YP_001169228.1| isocitrate dehydrogenase [Rhodobacter s... 668 0.0
ref|NP_696658.1| isocitrate dehydrogenase [Bifidobacterium ... 667 0.0
ref|YP_001260963.1| isocitrate dehydrogenase [Sphingomonas ... 667 0.0
ref|YP_883449.1| isocitrate dehydrogenase [Mycobacterium av... 667 0.0
ref|YP_001168561.1| isocitrate dehydrogenase [Rhodobacter s... 667 0.0
ref|ZP_03977360.1| isocitrate dehydrogenase (NADP(+)) [Bifi... 667 0.0
ref|ZP_03993927.1| isocitrate dehydrogenase [Mobiluncus mul... 667 0.0
ref|YP_568874.1| isocitrate dehydrogenase [Rhodopseudomonas... 667 0.0
emb|CAE04728.1| OSJNBa0043L24.16 [Oryza sativa (japonica cu... 667 0.0
ref|ZP_01046178.1| isocitrate dehydrogenase NADP-dependent ... 667 0.0
ref|XP_001485076.1| isocitrate dehydrogenase peroxisomal [P... 667 0.0
ref|YP_317907.1| isocitrate dehydrogenase [Nitrobacter wino... 666 0.0
ref|XP_821599.1| isocitrate dehydrogenase, putative [Trypan... 666 0.0
ref|YP_001241304.1| isocitrate dehydrogenase [Bradyrhizobiu... 666 0.0
ref|NP_982520.1| AAL022Wp [Ashbya gossypii ATCC 10895] >gi|... 666 0.0
ref|YP_001043974.1| isocitrate dehydrogenase [Rhodobacter s... 665 0.0
emb|CAH67563.1| OSIGBa0101P20.6 [Oryza sativa (indica culti... 665 0.0
ref|NP_001040134.1| isocitrate dehydrogenase [Bombyx mori] ... 665 0.0
gb|ABK25438.1| unknown [Picea sitchensis] 665 0.0
ref|YP_001042101.1| isocitrate dehydrogenase [Rhodobacter s... 665 0.0
ref|ZP_01130474.1| isocitrate dehydrogenase [marine actinob... 664 0.0
ref|XP_001676039.1| Hypothetical protein CBG17397 [Caenorha... 664 0.0
ref|YP_576902.1| isocitrate dehydrogenase [Nitrobacter hamb... 664 0.0
ref|XP_001457045.1| hypothetical protein GSPATT00022820001 ... 664 0.0
ref|YP_351602.1| isocitrate dehydrogenase [Rhodobacter spha... 664 0.0
ref|YP_353519.1| isocitrate dehydrogenase [Rhodobacter spha... 664 0.0
ref|YP_759895.1| isocitrate dehydrogenase [Hyphomonas neptu... 663 0.0
gb|ABI52605.1| isocitrate dehydrogenase [Gryllus firmus] 663 0.0
ref|XP_001670101.1| Hypothetical protein CBG21657 [Caenorha... 663 0.0
ref|XP_001426548.1| hypothetical protein GSPATT00029781001 ... 663 0.0
gb|ABL97438.1| isocitrate dehydrogenase [uncultured marine ... 663 0.0
ref|NP_013275.1| Cytosolic NADP-specific isocitrate dehydro... 662 0.0
ref|XP_001845030.1| isocitrate dehydrogenase [Culex pipiens... 662 0.0
ref|NP_509875.1| C34F6.8 [Caenorhabditis elegans] >gi|38747... 662 0.0
ref|XP_001020930.2| dehydrogenase, isocitrate/isopropylmala... 662 0.0
ref|XP_460289.1| hypothetical protein DEHA0E24134g [Debaryo... 662 0.0
ref|XP_001383685.1| Isocitrate dehydrogenase [NADP] peroxis... 662 0.0
gb|EDN59398.1| NADP-dependent isocitrate dehydrogenase [Sac... 662 0.0
ref|ZP_01018081.1| isocitrate dehydrogenase [Parvularcula b... 661 0.0
ref|NP_001093090.1| NADPH-specific isocitrate dehydrogenase... 661 0.0
ref|ZP_00960755.1| Isocitrate dehydrogenase [Roseovarius nu... 661 0.0
ref|YP_531457.1| isocitrate dehydrogenase [Rhodopseudomonas... 661 0.0
ref|ZP_01157336.1| isocitrate dehydrogenase [Oceanicola gra... 661 0.0
ref|YP_780531.1| isocitrate dehydrogenase [Rhodopseudomonas... 661 0.0
ref|XP_445184.1| unnamed protein product [Candida glabrata]... 661 0.0
sp|O13294|IDH2_CANTR Isocitrate dehydrogenase [NADP] peroxi... 660 0.0
ref|ZP_02963068.1| isocitrate dehydrogenase [Bifidobacteriu... 660 0.0
gb|AAT44354.1| isocitrate dehydrogenase [Crassostrea gigas] 659 0.0
ref|NP_926944.1| isocitrate dehydrogenase [Gloeobacter viol... 659 0.0
ref|XP_623673.2| PREDICTED: similar to Isocitrate dehydroge... 659 0.0
ref|XP_569234.1| isocitrate dehydrogenase (NADP+) [Cryptoco... 659 0.0
gb|ABO93633.1| isocitrate dehydrogenase 2 [Toxoplasma gondii] 659 0.0
ref|ZP_02731825.1| isocitrate dehydrogenase [Gemmata obscur... 658 0.0
ref|XP_455638.1| unnamed protein product [Kluyveromyces lac... 657 0.0
Sequences not found previously or not previously below threshold:
>ref|XP_536192.2| PREDICTED: similar to isocitrate dehydrogenase 2 (NADP+),
mitochondrial [Canis familiaris]
Length = 517
Score = 710 bits (1834), Expect = 0.0, Method: Composition-based stats.
Identities = 253/412 (61%), Positives = 309/412 (75%), Gaps = 6/412 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 108 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSA 167
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 168 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 227
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD + +AG ++ FS DG + +VY FP GG+ M
Sbjct: 228 PGWTKPITIGRHAHGDQYKATDFVVDRAGTFKIIFSPKDGSGAKEWEVYNFP-GGGVGMG 286
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +F+K YK F
Sbjct: 287 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDK 346
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 347 NKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 406
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 407 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEK 466
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLS 409
+ TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 467 VCVQTVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKNNLDKALGQ 517
>ref|XP_001903959.1| unnamed protein product [Podospora anserina]
emb|CAP61736.1| unnamed protein product [Podospora anserina]
Length = 461
Score = 710 bits (1833), Expect = 0.0, Method: Composition-based stats.
Identities = 272/407 (66%), Positives = 330/407 (81%), Gaps = 1/407 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TRVIW+ IK+K I PYLD+DLKYYDL ++ RD+TNDQVT D++
Sbjct: 53 AKIKVKNPVVELDGDEMTRVIWQDIKDKFITPYLDIDLKYYDLGLEYRDQTNDQVTIDAA 112
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KY V VKCATITPDEAR++EF LK+MW SPNGTIRN LGGTVFREPI+IP++PRLV
Sbjct: 113 EAIKKYSVGVKCATITPDEARVEEFKLKQMWLSPNGTIRNALGGTVFREPIVIPRVPRLV 172
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPIIIGRHAFGDQYRA D GKL + ++ + G E +++VY+F GG+A
Sbjct: 173 PGWKKPIIIGRHAFGDQYRAKDFVAPGPGKLSMVYTPE-GGEPQEIEVYKFQGGGGVAQT 231
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT++SI GFA ASF+LA+ + LPL+ +TKNTILK YD +FK IF L+D +YKE F+A
Sbjct: 232 QYNTDESITGFAHASFKLAIDKGLPLYMSTKNTILKKYDGRFKDIFQELYDTQYKEAFEA 291
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS GG+I+A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGK
Sbjct: 292 KGIWYEHRLIDDMVAQMIKSSGGYIMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGK 351
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
TFESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD+T +V+ F LEK
Sbjct: 352 TFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDDTPEVVAFAEALEK 411
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMML 408
A +DTV V G MTKDLAL GKT R YVTT E++ V +RL+ +
Sbjct: 412 ACIDTVDVDGIMTKDLALACGKTGREDYVTTSEYMVAVERRLKQSLK 458
>ref|NP_786984.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Bos taurus]
emb|CAA49207.1| isocitrate dehydrogenase (NADP+) [Bos taurus]
Length = 452
Score = 710 bits (1833), Expect = 0.0, Method: Composition-based stats.
Identities = 252/413 (61%), Positives = 312/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 42 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSA 101
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD + +AG ++ F+ DG + +VY FP +GG+ M
Sbjct: 162 PGWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFP-AGGVGMG 220
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +F+K YK +F
Sbjct: 221 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDK 280
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 281 HKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 340
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 341 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEK 400
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 401 VCVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGQQ 452
>sp|Q04467|IDHP_BOVIN Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAI02510.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Bos taurus]
Length = 452
Score = 709 bits (1832), Expect = 0.0, Method: Composition-based stats.
Identities = 252/413 (61%), Positives = 312/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 42 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSA 101
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD + +AG ++ F+ DG + +VY FP +GG+ M
Sbjct: 162 PGWTKPITIGRHAHGDQYKATDFVVDRAGTFKVVFTPKDGSGPKEWEVYNFP-AGGVGMG 220
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +F+K YK +F
Sbjct: 221 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQAIFEKHYKTEFDK 280
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 281 HKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 340
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 341 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEK 400
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 401 VCVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGQQ 452
>ref|NP_001026770.1| hypothetical protein LOC431056 [Gallus gallus]
emb|CAG31511.1| hypothetical protein [Gallus gallus]
Length = 452
Score = 709 bits (1830), Expect = 0.0, Method: Composition-based stats.
Identities = 252/412 (61%), Positives = 311/412 (75%), Gaps = 6/412 (1%)
Query: 3 KIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSY 62
+IKV +P+VEMDGDE TR+IW IKEKLILP +DV LKY+DL + RD+T+DQVT DS+
Sbjct: 43 RIKVANPVVEMDGDEMTRIIWAFIKEKLILPNVDVQLKYFDLGLPHRDKTDDQVTIDSAL 102
Query: 63 ATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVP 122
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLVP
Sbjct: 103 ATKKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162
Query: 123 HWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAM 182
W +PI IGRHA GDQY+ATD + K+G ++ F+ DG + +V+ FP GG+ M M
Sbjct: 163 GWTQPITIGRHAHGDQYKATDFVVNKSGTFKMVFTPKDGSGVKEWEVFNFP-GGGVGMGM 221
Query: 183 FNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQAL 242
+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK +F L
Sbjct: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTEFDKL 281
Query: 243 KITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKT 302
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGKT
Sbjct: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341
Query: 303 FESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKA 362
E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD+ ++IKF LEK
Sbjct: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDSNPELIKFAQTLEKV 401
Query: 363 TLDTVQVGGKMTKDLALMLGK----TNRSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + +V T +F+D + L +
Sbjct: 402 CVETVE-SGTMTKDLAGCIHGLANVKLNEHFVNTTDFLDAIKNTLDKALGKK 452
>sp|P54071|IDHP_MOUSE Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
dbj|BAC40149.1| unnamed protein product [Mus musculus]
gb|AAH60030.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Mus musculus]
dbj|BAE41142.1| unnamed protein product [Mus musculus]
dbj|BAE36505.1| unnamed protein product [Mus musculus]
dbj|BAE26628.1| unnamed protein product [Mus musculus]
gb|EDL07035.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial, isoform CRA_d
[Mus musculus]
Length = 452
Score = 708 bits (1829), Expect = 0.0, Method: Composition-based stats.
Identities = 253/413 (61%), Positives = 310/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 42 KRIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSA 101
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD + +AG +L F+ DG + +VY FP +GG+ M
Sbjct: 162 PGWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFP-AGGVGMG 220
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ ++++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 221 MYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDK 280
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 281 NKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 340
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 341 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEK 400
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
+ TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 401 VCVQTVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ 452
>ref|XP_001240510.1| isocitrate dehydrogenase NADP, mitochondrial precursor
[Coccidioides immitis RS]
gb|EAS28927.1| isocitrate dehydrogenase NADP, mitochondrial precursor
[Coccidioides immitis RS]
Length = 509
Score = 708 bits (1827), Expect = 0.0, Method: Composition-based stats.
Identities = 265/410 (64%), Positives = 328/410 (80%), Gaps = 2/410 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
KIKV +P+VE+DGDE TR+IW+ IK+K I PYLDVDLKYYDL ++ RD+T+D+VT D++
Sbjct: 101 KKIKVKNPVVELDGDEMTRIIWQDIKDKFIYPYLDVDLKYYDLGLEYRDQTDDKVTVDAA 160
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRLV
Sbjct: 161 EAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRLV 220
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPIIIGRHAFGDQYRATD + GKL L ++ +G E + VY+F + GIA
Sbjct: 221 PGWKKPIIIGRHAFGDQYRATDRLVPGPGKLELVYTPTNG-EPERITVYDF-QGAGIAQV 278
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT+DSI+GFA ASF+LAL + LP++ +TKNTILK YD +FK IF+ +++ EYK+ F+A
Sbjct: 279 QYNTDDSIRGFAHASFKLALLKGLPMYMSTKNTILKKYDGRFKDIFEEVYEAEYKKAFEA 338
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+K GG +IAMKNYDGDVQSDIVAQGFGSLGLMTS L TPDG
Sbjct: 339 KGIWYEHRLIDDMVAQMIKGDGGCVIAMKNYDGDVQSDIVAQGFGSLGLMTSTLTTPDGS 398
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +I+RG+LD T DV+ F LE+
Sbjct: 399 AFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIRRGQLDETPDVVTFAEQLER 458
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
A ++ V G MTKDLAL GK R ++VTT E++D V +RL++ + ++
Sbjct: 459 ACIEVVDEEGIMTKDLALSCGKKERDAWVTTREYMDAVERRLRSNLANAK 508
>ref|NP_766599.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Mus musculus]
gb|AAG43538.1|AF212319_1 NADP+-specific isocitrate dehydrogenase [Mus musculus]
Length = 452
Score = 708 bits (1827), Expect = 0.0, Method: Composition-based stats.
Identities = 253/413 (61%), Positives = 310/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 42 KRIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSA 101
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD + +AG +L F+ DG + +VY FP +GG+ M
Sbjct: 162 PGWTKPITIGRHAHGDQYKATDFVVDRAGTFKLVFTPKDGSSAKEWEVYNFP-AGGVGMG 220
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ ++++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 221 MYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDR 280
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 281 NKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 340
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 341 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEK 400
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
+ TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 401 VCVQTVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ 452
>gb|ACO14046.1| Isocitrate dehydrogenase, mitochondrial precursor [Esox lucius]
Length = 451
Score = 708 bits (1827), Expect = 0.0, Method: Composition-based stats.
Identities = 256/412 (62%), Positives = 310/412 (75%), Gaps = 6/412 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLIL +DV+LKYYDL + RD+TNDQVT DS+
Sbjct: 42 KRIKVSQPVVEMDGDEMTRIIWEFIKEKLILSNVDVELKYYDLGLPYRDQTNDQVTIDSA 101
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 102 LATQKYHVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W +PI IGRHAFGDQYRATD + + G ++ FS DG + + VY FP GG M
Sbjct: 162 PGWTQPITIGRHAFGDQYRATDFVVNQPGTFKMVFSPTDGSKGQEWGVYNFP-GGGCGMG 220
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+ +K PL+ +TKNTILK YD +FK IF+ +F YK +F
Sbjct: 221 MYNTDESISGFAHSCFQYAIGKKWPLYLSTKNTILKAYDGRFKDIFEEIFQANYKPEFDK 280
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
LKI YEHRLIDDMVAQ+LKS G F+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 281 LKIWYEHRLIDDMVAQVLKSDGAFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 340
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+IKF LE+
Sbjct: 341 TIEAEAAHGTVTRHYREHQKGNPTSTNPIASIFAWTRGLEHRGKLDGNPDLIKFALTLER 400
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNR----SSYVTTEEFIDEVAKRLQNMMLS 409
++TV+ G MTKDLA + ++ YV TE+F+D + K L +
Sbjct: 401 VCVETVE-SGVMTKDLAGCIHGLSKCKLNEHYVNTEDFLDAIKKNLDKALGK 451
>ref|NP_539708.1| isocitrate dehydrogenase [Brucella melitensis 16M]
ref|YP_221903.1| isocitrate dehydrogenase [Brucella abortus biovar 1 str. 9-941]
ref|YP_414607.1| isocitrate dehydrogenase [Brucella melitensis biovar Abortus 2308]
ref|YP_001259118.1| isocitrate dehydrogenase [Brucella ovis ATCC 25840]
ref|YP_001935116.1| Isocitrate/isopropylmalate dehydrogenase [Brucella abortus S19]
gb|AAL51972.1| ISOCITRATE DEHYDROGENASE (NADP) [Brucella melitensis 16M]
gb|AAX74542.1| isocitrate dehydrogenase, NADP-dependent [Brucella abortus biovar 1
str. 9-941]
emb|CAJ11177.1| Isocitrate/isopropylmalate dehydrogenase:Isocitrate dehydrogenase
NADP-dependent, eukaryotic [Brucella melitensis biovar
Abortus 2308]
gb|ABQ61375.1| isocitrate dehydrogenase, NADP-dependent [Brucella ovis ATCC 25840]
gb|ACD72642.1| Isocitrate/isopropylmalate dehydrogenase [Brucella abortus S19]
Length = 404
Score = 707 bits (1826), Expect = 0.0, Method: Composition-based stats.
Identities = 260/409 (63%), Positives = 323/409 (78%), Gaps = 5/409 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW+ IK+KLI PYLD+DLKYYDLS++ RD TNDQVT D+
Sbjct: 1 MAKIKVANPVVELDGDEMTRIIWQFIKDKLIHPYLDIDLKYYDLSVENRDATNDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDEAR++EF LK+MWKSPNGTIRNILGG +FREPII +PRL
Sbjct: 61 ANAIKEYGVGVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGVIFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W +PII+GRHAFGDQYRATD K G L ++F +DG + I+ +VY+ P S G+AM
Sbjct: 121 VPGWTQPIIVGRHAFGDQYRATDFKFPGKGTLTIKFVGEDG-QTIEHEVYQAP-SAGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI+ FA+ASF L+R P++ +TKNTILK YD +FK IF +FD E+K KF+
Sbjct: 179 AMYNLDESIREFARASFNYGLQRGYPVYLSTKNTILKAYDGRFKDIFQEVFDAEFKSKFE 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
KI YEHRLIDDMVA LK GG++ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 239 EKKIWYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+GEETSTNSIASIFAWTR + R KLDN D+ KF LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGLAHRAKLDNNADLKKFAETLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
K +DTV+ G MTKDLAL++G +++T F+D++ + LQ M +
Sbjct: 359 KVCVDTVE-SGFMTKDLALLIGPDQ--PWLSTTGFLDKIDENLQKAMAA 404
>ref|XP_955850.1| hypothetical protein NCU03857 [Neurospora crassa OR74A]
gb|EAA26614.1| hypothetical protein NCU03857 [Neurospora crassa OR74A]
Length = 462
Score = 707 bits (1826), Expect = 0.0, Method: Composition-based stats.
Identities = 266/407 (65%), Positives = 332/407 (81%), Gaps = 1/407 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
KIKV +P+VE+DGDE TR+IW+ IKEK I P+LD+DLKYYDL ++ RD+TNDQVT D++
Sbjct: 54 QKIKVKNPVVELDGDEMTRIIWQDIKEKFIYPFLDIDLKYYDLGLEYRDQTNDQVTIDAA 113
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KY V VKCATITPDE+R++EF LK+MW SPNGTIRN LGGTVFREPI+IP++PRLV
Sbjct: 114 EAIKKYSVGVKCATITPDESRVEEFKLKQMWLSPNGTIRNALGGTVFREPIVIPRVPRLV 173
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPIIIGRHAFGDQYRA D+ GKL++ ++ + G E + V+++ GG+A
Sbjct: 174 PGWKKPIIIGRHAFGDQYRAKDLVAPGPGKLQMVYTPE-GGEPQVIDVFDYKNGGGVAQT 232
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT++SI+GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF ++D +YKE F+A
Sbjct: 233 QYNTDESIEGFAHASFKLALDKGLPLYMSTKNTILKKYDGRFKDIFQQIYDTQYKEAFEA 292
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQM+KS GG+I+A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGK
Sbjct: 293 KKIWYEHRLIDDMVAQMIKSSGGYIMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGK 352
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
TFESEAAHGTVTRH+R+HQ+G +TSTN IASIFAWTR ++QRGKLDNT ++I F LEK
Sbjct: 353 TFESEAAHGTVTRHYREHQKGNQTSTNPIASIFAWTRGLVQRGKLDNTPELIAFAEALEK 412
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMML 408
A +DTV + G MTKDLAL GKT R +VTT E++ V +RL++ +
Sbjct: 413 ACIDTVDIDGIMTKDLALACGKTGREDWVTTSEYMAAVERRLKSTLK 459
>ref|XP_001226620.1| conserved hypothetical protein [Chaetomium globosum CBS 148.51]
gb|EAQ84679.1| conserved hypothetical protein [Chaetomium globosum CBS 148.51]
Length = 469
Score = 707 bits (1825), Expect = 0.0, Method: Composition-based stats.
Identities = 273/407 (67%), Positives = 328/407 (80%), Gaps = 1/407 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TRVIWK IKEK I PYLDVDLKYYDL ++ RD TNDQVT D++
Sbjct: 61 AKIKVKNPVVELDGDEMTRVIWKDIKEKFIFPYLDVDLKYYDLGLEYRDETNDQVTLDAA 120
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KY V VKCATITPDEAR++EF LK+MW SPNGTIRN LGGTVFREPI+IP+IPRLV
Sbjct: 121 EAIKKYSVGVKCATITPDEARVEEFKLKQMWLSPNGTIRNALGGTVFREPIVIPRIPRLV 180
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W+KPIIIGRHAFGDQYRA D+ + GKL + ++ G E +++V++F GG+A
Sbjct: 181 PGWKKPIIIGRHAFGDQYRAKDLVVPGPGKLSMVYTPA-GGEPQEIEVFQFKNGGGVAQT 239
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT++SI GFA ASF+LAL + LPL+ +TKNTILK YD +FK IF L+D YK +F+A
Sbjct: 240 QYNTDESITGFAHASFKLALDKGLPLYMSTKNTILKKYDGRFKDIFQELYDGGYKAQFEA 299
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS GG+I+A+KNYDGDVQSDIVAQGFGSLGLMTS+LITPDGK
Sbjct: 300 KGIWYEHRLIDDMVAQMIKSTGGYIMALKNYDGDVQSDIVAQGFGSLGLMTSVLITPDGK 359
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
TFESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T +V+ F LE+
Sbjct: 360 TFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPEVVAFAEGLER 419
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMML 408
A +DTV + G MTKDLAL GKT R YVTT E++ V +RL+ +
Sbjct: 420 ACIDTVDIDGIMTKDLALACGKTAREDYVTTSEYLSAVERRLKQSLK 466
>ref|NP_955858.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Danio rerio]
gb|AAH48041.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Danio rerio]
gb|AAH63967.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Danio rerio]
Length = 449
Score = 707 bits (1825), Expect = 0.0, Method: Composition-based stats.
Identities = 252/412 (61%), Positives = 312/412 (75%), Gaps = 6/412 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+I+V P+VEMDGDE TR+IW+ IKEKLIL ++VDLKYYDL + RD+T+DQVT DS+
Sbjct: 40 KRIQVAQPVVEMDGDEMTRIIWEFIKEKLILTNVNVDLKYYDLGLPYRDQTDDQVTIDSA 99
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 100 IATKKYNVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 159
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W + I IGRHAFGDQY+ATD + + GK ++ F+ DG +N + +VY+FP GG M
Sbjct: 160 PGWTQAITIGRHAFGDQYKATDFVVNQPGKFKMVFTPADGSKNKEWEVYDFP-GGGCGMG 218
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF ++F+K YK +F
Sbjct: 219 MYNTDESITGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQDIFEKNYKPEFDK 278
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
LKI YEHRLIDDMVAQ+LKS G F+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 279 LKIWYEHRLIDDMVAQVLKSSGAFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 338
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+IKF LE+
Sbjct: 339 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNPDLIKFSQTLER 398
Query: 362 ATLDTVQVGGKMTKDLALMLGK----TNRSSYVTTEEFIDEVAKRLQNMMLS 409
++TV+ G MTKDLA + YV T +F+D + L +
Sbjct: 399 VCVETVE-SGVMTKDLAGCIHGLANCKLNEHYVNTTDFLDAIKTNLDKALGK 449
>ref|NP_001014183.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [Rattus
norvegicus]
sp|P56574|IDHP_RAT Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAH76398.1| Similar to NADP+-specific isocitrate dehydrogenase [Rattus
norvegicus]
gb|EDM08608.1| similar to NADP+-specific isocitrate dehydrogenase, isoform CRA_b
[Rattus norvegicus]
Length = 452
Score = 706 bits (1824), Expect = 0.0, Method: Composition-based stats.
Identities = 252/413 (61%), Positives = 310/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 42 KRIKVEKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSA 101
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD + +AG +L F+ DG + +VY FP +GG+ M
Sbjct: 162 PGWTKPITIGRHAHGDQYKATDFVVDRAGMFKLVFTPKDGSGAKEWEVYNFP-AGGVGMG 220
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ ++++K PL+ +TKNTI+K YD +FK IF +FDK YK F
Sbjct: 221 MYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTIMKAYDGRFKDIFQEIFDKHYKTDFDK 280
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 281 NKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 340
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 341 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEK 400
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
+ TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 401 VCVQTVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGKQ 452
>ref|XP_754749.1| isocitrate dehydrogenase Idp1 [Aspergillus fumigatus Af293]
gb|EAL92711.1| isocitrate dehydrogenase Idp1, putative [Aspergillus fumigatus
Af293]
Length = 501
Score = 706 bits (1824), Expect = 0.0, Method: Composition-based stats.
Identities = 266/409 (65%), Positives = 333/409 (81%), Gaps = 2/409 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TR+IW+ I+EKLILPYLD+DLKYYDL I+ RD+T+D+VT +++
Sbjct: 94 TKIKVKNPVVELDGDEMTRIIWQEIREKLILPYLDIDLKYYDLGIEYRDQTDDKVTVEAA 153
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRLV
Sbjct: 154 EAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRLV 213
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPIIIGRHAFGDQYRATDI + GKL L ++ ++G E +KVY+F GG+A
Sbjct: 214 PGWNKPIIIGRHAFGDQYRATDIVVPGPGKLELVYTPENG-EPQAIKVYDFT-GGGVAQT 271
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT+DSI+GFA +SF++AL + LPL+ +TKNTILK YD +FK IF +++ YK++F A
Sbjct: 272 QYNTDDSIRGFAHSSFKMALMKGLPLYMSTKNTILKKYDGRFKDIFQEIYESTYKKEFDA 331
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS+GGF++A+KNYDGDVQSD+VAQGFGSLGLMTS L TPDG
Sbjct: 332 KGIWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDVVAQGFGSLGLMTSTLTTPDGS 391
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+ F LE+
Sbjct: 392 AFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVTFAEELER 451
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSS 410
A +D V G MTKDLAL G+ R ++VTT+E++ V +RL++ + +
Sbjct: 452 ACIDVVNEEGIMTKDLALACGRKEREAWVTTKEYLAAVERRLKSNLKAR 500
>gb|EDP52872.1| isocitrate dehydrogenase Idp1, putative [Aspergillus fumigatus
A1163]
Length = 501
Score = 706 bits (1824), Expect = 0.0, Method: Composition-based stats.
Identities = 266/409 (65%), Positives = 333/409 (81%), Gaps = 2/409 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KIKV +P+VE+DGDE TR+IW+ I+EKLILPYLD+DLKYYDL I+ RD+T+D+VT +++
Sbjct: 94 TKIKVKNPVVELDGDEMTRIIWQEIREKLILPYLDIDLKYYDLGIEYRDQTDDKVTVEAA 153
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
A KYGV VKCATITPDEAR++EF LK+MW SPNGTIRNILGGTVFREPI+IP+IPRLV
Sbjct: 154 EAIKKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPRIPRLV 213
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPIIIGRHAFGDQYRATDI + GKL L ++ ++G E +KVY+F GG+A
Sbjct: 214 PGWNKPIIIGRHAFGDQYRATDIVVPGPGKLELVYTPENG-EPQAIKVYDFT-GGGVAQT 271
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
+NT+DSI+GFA +SF++AL + LPL+ +TKNTILK YD +FK IF +++ YK++F A
Sbjct: 272 QYNTDDSIRGFAHSSFKMALMKGLPLYMSTKNTILKKYDGRFKDIFQEIYESTYKKEFDA 331
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVAQM+KS+GGF++A+KNYDGDVQSD+VAQGFGSLGLMTS L TPDG
Sbjct: 332 KGIWYEHRLIDDMVAQMIKSEGGFVMALKNYDGDVQSDVVAQGFGSLGLMTSTLTTPDGS 391
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
FESEAAHGTVTRH+R+HQ+G ETSTN IASIFAWTR +IQRGKLD T DV+ F LE+
Sbjct: 392 AFESEAAHGTVTRHYREHQKGRETSTNPIASIFAWTRGLIQRGKLDETPDVVTFAEELER 451
Query: 362 ATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSS 410
A +D V G MTKDLAL G+ R ++VTT+E++ V +RL++ + +
Sbjct: 452 ACIDVVNEEGIMTKDLALACGRKEREAWVTTKEYLAAVERRLKSNLKAR 500
>ref|NP_698203.1| isocitrate dehydrogenase [Brucella suis 1330]
ref|YP_001593041.1| isocitrate dehydrogenase, NADP-dependent [Brucella canis ATCC
23365]
ref|YP_001627868.1| isocitrate dehydrogenase, NADP-dependent [Brucella suis ATCC 23445]
gb|AAN30118.1| isocitrate dehydrogenase, NADP-dependent [Brucella suis 1330]
gb|ABX62270.1| isocitrate dehydrogenase, NADP-dependent [Brucella canis ATCC
23365]
gb|ABY38298.1| isocitrate dehydrogenase, NADP-dependent [Brucella suis ATCC 23445]
Length = 404
Score = 706 bits (1823), Expect = 0.0, Method: Composition-based stats.
Identities = 259/409 (63%), Positives = 323/409 (78%), Gaps = 5/409 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +P+VE+DGDE TR+IW+ IK+KLI PYLD+DLKYYDLS++ RD TNDQVT D+
Sbjct: 1 MAKIKVANPVVELDGDEMTRIIWQFIKDKLIHPYLDIDLKYYDLSVENRDATNDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDEAR++EF LK+MWKSPNGTIRNILGG +FREPII +PRL
Sbjct: 61 ANAIKEYGVGVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGVIFREPIICKNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W +PII+GRHAFGDQYRATD K G L ++F +DG + I+ +VY+ P S G+AM
Sbjct: 121 VPGWTQPIIVGRHAFGDQYRATDFKFPGKGTLTIKFVGEDG-QTIEHEVYQAP-SAGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
AM+N ++SI+ FA+ASF L+R P++ +TKNTILK YD +FK IF +FD E+K KF+
Sbjct: 179 AMYNLDESIREFARASFNYGLQRGYPVYLSTKNTILKAYDGRFKDIFQEVFDAEFKSKFE 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
KI YEHRLIDDMVA LK GG++ A KNYDGDVQSDIVAQGFGSLGLMTS+L+TPDG
Sbjct: 239 EKKIWYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R++Q+GEETSTNSIASIFAWTR + R KLDN D+ KF LE
Sbjct: 299 KTVEAEAAHGTVTRHYRQYQKGEETSTNSIASIFAWTRGLAHRAKLDNNADLKKFAETLE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLS 409
K +DTV+ G MTKDLAL++G +++T F+D++ + LQ M +
Sbjct: 359 KVCVDTVE-SGFMTKDLALLIGPDQ--PWLSTTGFLDKIDENLQKAMAA 404
>ref|XP_001107627.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 1
[Macaca mulatta]
ref|XP_001107810.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 2
[Macaca mulatta]
ref|XP_001107875.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 3
[Macaca mulatta]
ref|XP_001107934.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 4
[Macaca mulatta]
ref|XP_001107992.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 5
[Macaca mulatta]
Length = 414
Score = 706 bits (1822), Expect = 0.0, Method: Composition-based stats.
Identities = 243/414 (58%), Positives = 311/414 (75%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VE+ GDE TR+IW+LIKEKLI PY+++DL+ YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKISGGSVVELQGDEMTRIIWELIKEKLIFPYVELDLQSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVCIETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>ref|XP_510589.2| PREDICTED: isocitrate dehydrogenase 2 (NADP+), mitochondrial
isoform 4 [Pan troglodytes]
Length = 452
Score = 706 bits (1822), Expect = 0.0, Method: Composition-based stats.
Identities = 251/413 (60%), Positives = 310/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++D+ LKY+DL + RD+T+DQVT DS+
Sbjct: 42 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSA 101
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD +AG ++ F+ DG + +VY FP +GG+ M
Sbjct: 162 PGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMG 220
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 221 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDK 280
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 281 NKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 340
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 341 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEK 400
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 401 VCVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452
>sp|Q9Z2K9|IDHC_MICME Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02924.1| cytosolic NADP-dependent isocitrate dehydrogenase [Microtus
mexicanus]
Length = 414
Score = 705 bits (1821), Expect = 0.0, Method: Composition-based stats.
Identities = 245/414 (59%), Positives = 310/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLILPY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + F+ DG + + V+ F + GG+AM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITFTPKDGSQKVTYLVHSFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G+ETSTN IASIFAW+R + R +LDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVCIETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAK 413
>ref|XP_001369305.1| PREDICTED: hypothetical protein [Monodelphis domestica]
Length = 455
Score = 705 bits (1820), Expect = 0.0, Method: Composition-based stats.
Identities = 254/413 (61%), Positives = 310/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+T+DQVT DS+
Sbjct: 45 KRIKVDKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPHRDQTDDQVTIDSA 104
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 105 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 164
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W +PI IGRHA GDQY+ATD + KAG ++ F+ DG + +VY FP +GG+ M
Sbjct: 165 PGWTRPITIGRHAHGDQYKATDFVVDKAGTFKMVFTPKDGSGAKEWEVYNFP-AGGVGMG 223
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 224 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDK 283
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 284 NKIWYEHRLIDDMVAQVLKSNGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 343
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+IKF LEK
Sbjct: 344 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIKFAQTLEK 403
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
+ TV+ G MTKDLA + + Y+ T +F+D + L +
Sbjct: 404 VCVQTVE-SGAMTKDLAGCIHGLSNVKLNEHYLNTGDFLDTIKNNLDKALGQK 455
>ref|XP_001095686.1| PREDICTED: isocitrate dehydrogenase 2 (NADP+), mitochondrial
[Macaca mulatta]
sp|Q4R502|IDHP_MACFA Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
dbj|BAE01823.1| unnamed protein product [Macaca fascicularis]
Length = 452
Score = 705 bits (1820), Expect = 0.0, Method: Composition-based stats.
Identities = 251/413 (60%), Positives = 310/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++D+ LKY+DL + RD+T+DQVT DS+
Sbjct: 42 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSA 101
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD +AG ++ F+ DG + +VY FP +GG+ M
Sbjct: 162 PGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMG 220
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 221 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDK 280
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 281 NKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 340
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 341 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEK 400
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 401 VCVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452
>emb|CAM77136.1| Isocitrate/isopropylmalate dehydrogenase [Magnetospirillum
gryphiswaldense MSR-1]
Length = 405
Score = 704 bits (1819), Expect = 0.0, Method: Composition-based stats.
Identities = 254/408 (62%), Positives = 321/408 (78%), Gaps = 5/408 (1%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M+KIKV +PIVE+DGDE TR+IWK IK+KLILPYLDVDLKYYDL ++ RD TNDQVT D+
Sbjct: 1 MNKIKVANPIVELDGDEMTRIIWKFIKDKLILPYLDVDLKYYDLGVEYRDETNDQVTIDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A +YGV VKCATITPDEAR+KEFNLK+MWKSPNGTIRNIL GTVFREPII +PRL
Sbjct: 61 AEAIKQYGVGVKCATITPDEARVKEFNLKKMWKSPNGTIRNILDGTVFREPIICQNVPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPI+IGRHAFGDQYRATD K+ G L ++F +DG + I+ +V+ FP S G+AM
Sbjct: 121 VPGWTKPIVIGRHAFGDQYRATDFKVPGPGILTMKFVGEDG-QVIEHEVFNFP-SSGVAM 178
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N ++SI+GFA+A L +K P++ +TKNTILK YD +FK IF +++KE+K +F
Sbjct: 179 GMYNLDESIRGFARACMNYGLAKKWPVYLSTKNTILKAYDGRFKDIFQEVYEKEFKAEFD 238
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
+TYEHRLIDDMVA LK G F+ A KNYDGDVQSD VAQGFGSLGLMTS+L++PDG
Sbjct: 239 KYGMTYEHRLIDDMVASALKWSGEFVWACKNYDGDVQSDTVAQGFGSLGLMTSVLLSPDG 298
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R+HQ+G+ETSTN IASIFAWTR ++ R + DNT +V KF LE
Sbjct: 299 KTVEAEAAHGTVTRHYREHQKGKETSTNPIASIFAWTRGLLYRAQFDNTPEVAKFATALE 358
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMML 408
+ ++TV+ G MTKDLA+++G ++TT +F+D++ + L+ M
Sbjct: 359 EVCVETVEA-GFMTKDLAILIGPDQ--PWLTTTQFLDKLDENLKKKMG 403
>ref|NP_113698.1| isocitrate dehydrogenase 1 (NADP+), soluble [Rattus norvegicus]
sp|P41562|IDHC_RAT Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAA59356.1| cytosolic NADP-dependent isocitrate dehydrogenase
gb|EDL98861.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98863.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98864.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
gb|EDL98865.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Rattus
norvegicus]
Length = 414
Score = 704 bits (1819), Expect = 0.0, Method: Composition-based stats.
Identities = 245/414 (59%), Positives = 312/414 (75%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS+ +VEM GDE TR+IW+LIKEKLILPY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSRKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V++F + GG+AM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHDFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK KF+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSKFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAW+R + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWSRGLAHRAKLDNNTELSFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVCIETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAK 413
>ref|XP_421965.2| PREDICTED: similar to cytosolic NADP-dependent isocitrate
dehydrogenase [Gallus gallus]
Length = 415
Score = 704 bits (1819), Expect = 0.0, Method: Composition-based stats.
Identities = 245/412 (59%), Positives = 306/412 (74%), Gaps = 4/412 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TRVIW+LIKEKLI PY+D+DL YDL I+ RD TND+VT ++
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIEHRDATNDKVTVEA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V +KCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYHVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPI+IGRHA+GDQYRATD + GK+ + ++ DG + + V+ F GG+AM
Sbjct: 121 VSGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEMTYTPGDGGKPVTYLVHNFESCGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SIK FA +SF++AL + PL+ +TKNTILK YD +FK IF ++D+EYK +F+
Sbjct: 181 GMYNLDQSIKDFAHSSFQMALSKGWPLYMSTKNTILKRYDGRFKDIFQEIYDREYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ LKS+GGF+ A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G+ETSTN IASIFAWTR + R KLDN + F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWTRGLAHRAKLDNNTSLKTFATALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLS 409
+ ++T++ G MTKDLA + RS Y+ T EF+D++A L+ + S
Sbjct: 361 EVCIETIE-SGFMTKDLAACIKGLPNVTRSDYLNTFEFMDKLAANLKGKLAS 411
>ref|NP_001009276.1| cytosolic NADP-isocitrate dehydrogenase [Ovis aries]
sp|Q6XUZ5|IDHC_SHEEP Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAP41947.1| cytosolic NADP-isocitrate dehydrogenase [Ovis aries]
Length = 414
Score = 704 bits (1819), Expect = 0.0, Method: Composition-based stats.
Identities = 246/414 (59%), Positives = 307/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS +VEM GDE TR+IW+LIKEKLI PY+D+DL YDLSI+ RD TNDQVTKD+
Sbjct: 1 MSHKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVDLDLHSYDLSIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG V+ F +SGG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEICYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
MFN + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMFNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + LQ + +
Sbjct: 361 EVCIETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAK 413
>sp|Q9Z2K8|IDHC_MICOH Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD02925.1| cytosolic NADP-dependent isocitrate dehydrogenase [Microtus
ochrogaster]
Length = 414
Score = 704 bits (1818), Expect = 0.0, Method: Composition-based stats.
Identities = 244/414 (58%), Positives = 310/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLILPY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRIIWELIKEKLILPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPKDGSQKVTYLVHSFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G+ETSTN IASIFAW+R + R +LDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLAHRARLDNNTELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVCIETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKAKLAQAK 413
>ref|NP_851355.2| isocitrate dehydrogenase 1 (NADP+), soluble [Bos taurus]
gb|AAI03369.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Bos taurus]
Length = 414
Score = 704 bits (1818), Expect = 0.0, Method: Composition-based stats.
Identities = 243/414 (58%), Positives = 307/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS+ +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG V+ F +SGG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + LQ + +
Sbjct: 361 EVCIETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAK 413
>ref|NP_002159.2| isocitrate dehydrogenase 2 (NADP+), mitochondrial precursor [Homo
sapiens]
sp|P48735|IDHP_HUMAN Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAH09244.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Homo sapiens]
gb|AAH71828.1| Isocitrate dehydrogenase 2 (NADP+), mitochondrial [Homo sapiens]
gb|EAX02082.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial, isoform CRA_a
[Homo sapiens]
gb|ABM83743.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [synthetic
construct]
gb|ABM87062.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial [synthetic
construct]
Length = 452
Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats.
Identities = 251/413 (60%), Positives = 311/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++D+ LKY+DL + RD+T+DQVT DS+
Sbjct: 42 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSA 101
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD +AG ++ F+ DG + +VY FP +GG+ M
Sbjct: 162 PGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMG 220
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 221 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDK 280
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 281 NKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 340
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F +LEK
Sbjct: 341 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEK 400
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 401 VCVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452
>gb|ABE98244.1| mitochondrial isocitrate dehydrogenase 2-like [Oreochromis
mossambicus]
Length = 452
Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats.
Identities = 253/412 (61%), Positives = 313/412 (75%), Gaps = 6/412 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV +P+VEMDGDE TR+IW+ IKEKLIL +DV+LKY+DL + RD+T+DQVT DS+
Sbjct: 43 KRIKVANPVVEMDGDEMTRIIWEFIKEKLILTNVDVELKYFDLGLPYRDQTDDQVTIDSA 102
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 103 LATKKYSVAVKCATITPDEARVEEFGLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 162
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W +PI IGRHAFGDQYRATD + + GK ++ FS DG + + +V++FP +GG M
Sbjct: 163 PGWTQPITIGRHAFGDQYRATDFVVDQPGKFKIVFSPADGSTSKEWEVFDFP-AGGCGMG 221
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+ +K PL+ +TKNTILK YD +FK IF ++F+K YK +F
Sbjct: 222 MYNTDESITGFAHSCFQYAIGKKWPLYMSTKNTILKAYDGRFKDIFQDIFEKNYKPEFDK 281
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
LKI YEHRLIDDMVAQ+LKS G F+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 282 LKIWYEHRLIDDMVAQVLKSSGAFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 341
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+IKF LE+
Sbjct: 342 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNPDLIKFAQTLEQ 401
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLS 409
+ TV+ G MTKDLA + + YV T +F+D + L +
Sbjct: 402 VCVATVE-SGTMTKDLAGCIHGLSNVKLNEHYVNTTDFLDAIKTNLDKALGK 452
>ref|XP_001778805.1| predicted protein [Physcomitrella patens subsp. patens]
gb|EDQ56391.1| predicted protein [Physcomitrella patens subsp. patens]
Length = 411
Score = 703 bits (1816), Expect = 0.0, Method: Composition-based stats.
Identities = 255/409 (62%), Positives = 325/409 (79%), Gaps = 4/409 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+KI V +PIVEMDGDE TR+IWK+IK+KLI P+LD+DLKY+DL I+ RD T+D+VT +S+
Sbjct: 4 AKIHVANPIVEMDGDEMTRIIWKMIKDKLIFPFLDLDLKYFDLGIEHRDATDDRVTIESA 63
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR+KE+NLK MW+SPNGTIRNIL GTVFREPI+ IP+LV
Sbjct: 64 EATKKYNVAVKCATITPDEARVKEYNLKSMWRSPNGTIRNILNGTVFREPILCKNIPKLV 123
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W PI IGRHAFGDQY+ATD K GKL++ F ++G E DL VY+F +GG+A+
Sbjct: 124 PGWTSPICIGRHAFGDQYKATDAVFKGPGKLKMVFVPENGGETQDLTVYDFEGAGGVALT 183
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKE-YKEKFQ 240
M+NT++SI+ FA++S +A ++K PL+ +TKNTILK YD +FK IF ++++E +K KF
Sbjct: 184 MYNTDESIRSFAESSMAMAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEQEGWKAKFD 243
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD++AQGFGSLGLMTS+L+ PDG
Sbjct: 244 AAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDMLAQGFGSLGLMTSVLVCPDG 303
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAWTR + RGKLD + ++ F LE
Sbjct: 304 KTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLSHRGKLDGNEKLVDFATKLE 363
Query: 361 KATLDTVQVGGKMTKDLALMLGKTN--RSSYVTTEEFIDEVAKRLQNMM 407
+A + TV+ GKMTKDLAL++ + R +Y+ TEEFID VA+ L++ +
Sbjct: 364 QACVGTVE-NGKMTKDLALLIHGSKLSRDTYLNTEEFIDAVAEELKSKL 411
>emb|CAG38738.1| IDH1 [Homo sapiens]
Length = 414
Score = 703 bits (1816), Expect = 0.0, Method: Composition-based stats.
Identities = 243/414 (58%), Positives = 311/414 (75%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A K+ V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ +++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVSIETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>gb|ABU41004.1| isocitrate dehydrogenase 1 [Anser anser]
Length = 415
Score = 703 bits (1816), Expect = 0.0, Method: Composition-based stats.
Identities = 246/412 (59%), Positives = 307/412 (74%), Gaps = 4/412 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TRVIW+LIKEKLI PY+D+DL YDL I+ RD TND+VT ++
Sbjct: 1 MSKKIHGGSVVEMQGDEMTRVIWELIKEKLIFPYVDLDLHSYDLGIEHRDATNDKVTVEA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V +KCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYHVGIKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPI+IGRHA+GDQYRATD + GK+ + ++ DG + + V+ F GG+AM
Sbjct: 121 VSGWVKPIVIGRHAYGDQYRATDFVVPGPGKVEMTYTPGDGGKPVTYLVHNFESCGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
MFN + SIK FA +SF++AL + PL+ +TKNTILK YD +FK IF ++D+EYK +F+
Sbjct: 181 GMFNLDQSIKDFAHSSFQMALSKGWPLYMSTKNTILKRYDGRFKDIFQEIYDREYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ LKS+GGF+ A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 AKKIWYEHRLIDDMVAQALKSEGGFVWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G+ETSTN IASIFAWTR + R KLDN + F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWTRGLAHRAKLDNNTSLKTFAAALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLS 409
+ ++T++ G MTKDLA + RS Y+ T EF+D++A+ L+ + S
Sbjct: 361 EVCIETIE-SGFMTKDLAACIKGLPNVTRSDYLNTFEFMDKLAENLKGKLAS 411
>ref|XP_850187.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 2 [Canis familiaris]
ref|XP_536047.2| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) isoform 1 [Canis familiaris]
Length = 414
Score = 703 bits (1815), Expect = 0.0, Method: Composition-based stats.
Identities = 242/414 (58%), Positives = 307/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS+ +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG E + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGSEKMTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + L + +
Sbjct: 361 EVCVETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLNIKLAQAK 413
>ref|NP_005887.2| isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens]
sp|O75874|IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
pdb|1T09|A Chain A, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex Nadp
pdb|1T09|B Chain B, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex Nadp
pdb|1T0L|A Chain A, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|B Chain B, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|C Chain C, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
pdb|1T0L|D Chain D, Crystal Structure Of Human Cytosolic Nadp(+)-Dependent
Isocitrate Dehydrogenase In Complex With Nadp,
Isocitrate, And Calcium(2+)
gb|AAD29284.1|AF113917_1 NADP+-dependent isocitrate dehydrogenase [Homo sapiens]
gb|AAH12846.1| IDH1 protein [Homo sapiens]
emb|CAG46496.1| IDH1 [Homo sapiens]
gb|AAX93221.1| unknown [Homo sapiens]
gb|EAW70439.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|EAW70441.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|EAW70442.1| isocitrate dehydrogenase 1 (NADP+), soluble, isoform CRA_a [Homo
sapiens]
gb|ABM82361.1| isocitrate dehydrogenase 1 (NADP+), soluble [synthetic construct]
gb|ABW03396.1| isocitrate dehydrogenase 1 (NADP+), soluble [synthetic construct]
Length = 414
Score = 703 bits (1814), Expect = 0.0, Method: Composition-based stats.
Identities = 243/414 (58%), Positives = 311/414 (75%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A K+ V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ +++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVSIETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>emb|CAA49208.1| isocitrate dehydrogenase (NADP+) [Homo sapiens]
Length = 452
Score = 703 bits (1814), Expect = 0.0, Method: Composition-based stats.
Identities = 251/413 (60%), Positives = 311/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++D+ LKY+DL + RD+T+DQVT DS+
Sbjct: 42 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSA 101
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD +AG ++ F+ DG + +VY FP +GG+ M
Sbjct: 162 PGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMG 220
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 221 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDK 280
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 281 NKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 340
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F +LEK
Sbjct: 341 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEK 400
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 401 VCVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTMDFLDTIKSNLDRALGRQ 452
>pdb|1LWD|A Chain A, Crystal Structure Of Nadp-Dependent Isocitrate
Dehydrogenase From Porcine Heart Mitochondria
pdb|1LWD|B Chain B, Crystal Structure Of Nadp-Dependent Isocitrate
Dehydrogenase From Porcine Heart Mitochondria
Length = 413
Score = 703 bits (1814), Expect = 0.0, Method: Composition-based stats.
Identities = 252/413 (61%), Positives = 310/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 3 QRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSA 62
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 63 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 122
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD + +AG ++ F+ DG +VY FP +GG+ M
Sbjct: 123 PGWTKPITIGRHAHGDQYKATDFVVDRAGTFKIVFTPKDGSSAKQWEVYNFP-AGGVGMG 181
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +F+K YK F
Sbjct: 182 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDK 241
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 242 YKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 301
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 302 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEK 361
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 362 VCVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGRQ 413
>ref|NP_001088022.1| hypothetical protein LOC494713 [Xenopus laevis]
gb|AAH82651.1| LOC494713 protein [Xenopus laevis]
Length = 415
Score = 702 bits (1813), Expect = 0.0, Method: Composition-based stats.
Identities = 244/412 (59%), Positives = 308/412 (74%), Gaps = 4/412 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TRVIW LIKEKLILPY+++DL YDL ++ RD T+DQVT D+
Sbjct: 1 MSKKINGGSVVEMQGDEMTRVIWDLIKEKLILPYVELDLHSYDLGMENRDATDDQVTVDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V +KCATITPDE R++EFNLK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGIKCATITPDEKRVEEFNLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + F+ DG E I ++ F GG+A+
Sbjct: 121 VSGWIKPIIIGRHAYGDQYRATDFVVPGPGKVEISFTPKDGGEAIKYVIHNFEDCGGVAL 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+NT+ SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF +++KEYK +F+
Sbjct: 181 GMYNTDQSIRDFAHSSFQMALSKSWPLYMSTKNTILKRYDGRFKDIFQEIYEKEYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+LI PDG
Sbjct: 241 ENKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLICPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R HQ+G+ETSTN IASIFAW+R + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMHQKGQETSTNPIASIFAWSRGLDHRAKLDNNQELKNFATALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLS 409
+ ++T++ G MTKDLA + R Y++T EF+D++ + LQ + +
Sbjct: 361 EVCIETIEA-GFMTKDLAACIKGLPNVQRGDYLSTFEFMDKLGENLQLKLAA 411
>sp|P33198|IDHP_PIG Isocitrate dehydrogenase [NADP], mitochondrial precursor
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) (ICD-M)
gb|AAA31089.1| NADPH-specific isocitrate dehydrogenase
Length = 421
Score = 702 bits (1813), Expect = 0.0, Method: Composition-based stats.
Identities = 252/413 (61%), Positives = 310/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++DV LKY+DL + RD+TNDQVT DS+
Sbjct: 11 QRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSA 70
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 71 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 130
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD + +AG ++ F+ DG +VY FP +GG+ M
Sbjct: 131 PGWTKPITIGRHAHGDQYKATDFVVDRAGTFKIVFTPKDGSSAKQWEVYNFP-AGGVGMG 189
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +F+K YK F
Sbjct: 190 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDK 249
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 250 YKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 309
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F LEK
Sbjct: 310 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEK 369
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 370 VCVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGRQ 421
>dbj|BAD96636.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial precursor variant
[Homo sapiens]
Length = 452
Score = 702 bits (1813), Expect = 0.0, Method: Composition-based stats.
Identities = 250/413 (60%), Positives = 311/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++D+ LKY+DL + RD+T+DQVT DS+
Sbjct: 42 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSA 101
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD +AG ++ F+ DG + +VY FP +GG+ M
Sbjct: 162 PGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMG 220
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK Y+ F
Sbjct: 221 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYETDFDK 280
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 281 NKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 340
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F +LEK
Sbjct: 341 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEK 400
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 401 VCVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452
>gb|EEJ98364.1| isocitrate dehydrogenase (NADP) [Thermomonospora curvata DSM 43183]
Length = 407
Score = 702 bits (1813), Expect = 0.0, Method: Composition-based stats.
Identities = 254/407 (62%), Positives = 317/407 (77%), Gaps = 3/407 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
M KIKV P+VE+DGDE TR+IWK IK++LILPYLD+DLKYYDL IQ RD T+DQVT D+
Sbjct: 1 MPKIKVAGPVVELDGDEMTRIIWKFIKDQLILPYLDIDLKYYDLGIQNRDATDDQVTVDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KYGV VKCATITPDEAR++EF LK+MW+SPNGTIRNILGG VFREPII+ IPRL
Sbjct: 61 ANAIKKYGVGVKCATITPDEARVEEFGLKQMWRSPNGTIRNILGGVVFREPIIVSNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
VP W KPI+IGRHA GDQY+ATD K+ G L + ++ DDG E I +V +P+ GG+AM
Sbjct: 121 VPGWTKPIVIGRHAHGDQYKATDFKVPGPGTLTITYTPDDGSEPIQFEVARYPEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N SI+ FA+ASF L R P++ +TKNTILK YD FK +F +++ E+KE+F+
Sbjct: 181 GMYNFRKSIEDFARASFRYGLDRNYPVYLSTKNTILKAYDGMFKDVFAEIYENEFKEEFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A +TYEHRLIDDMVA LK +GG++ A KNYDGDVQSD VAQGFGSLGLMTS+L+TPDG
Sbjct: 241 ARGLTYEHRLIDDMVACALKWEGGYVWACKNYDGDVQSDTVAQGFGSLGLMTSVLMTPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
+T E+EAAHGTVTRH+R HQ+G+ TSTN IASIFAWTR + RGKLDNT +VIKF LE
Sbjct: 301 RTVEAEAAHGTVTRHYRLHQQGKPTSTNPIASIFAWTRGLAHRGKLDNTPEVIKFAETLE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMM 407
+ ++TV+ G+MTKDLAL++ K ++TT+EF+ + LQ +
Sbjct: 361 QVCIETVE-SGQMTKDLALLISKDQ--PWLTTQEFLHALDVNLQKKI 404
>gb|AAC64182.1| NADP-dependent isocitrate dehydrogenase [Glycine max]
Length = 416
Score = 702 bits (1813), Expect = 0.0, Method: Composition-based stats.
Identities = 261/413 (63%), Positives = 321/413 (77%), Gaps = 3/413 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
KI+V +PIVEMDGDE TRVIWKLIK+KLI PYL++D+KY+DL + RD TND+VT +S+
Sbjct: 4 QKIRVGNPIVEMDGDEMTRVIWKLIKDKLIFPYLELDIKYFDLGLPHRDATNDRVTIESA 63
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
ATLKY VA+KCATITPDEAR+KEFNLK+MW+SPNGTIRNIL GTVFREPII IPRLV
Sbjct: 64 EATLKYNVAIKCATITPDEARVKEFNLKQMWRSPNGTIRNILNGTVFREPIICKNIPRLV 123
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
W KPI IGRHAFGDQYRATD IK GKL+L F+ + +L+VY F +GGIA++
Sbjct: 124 SGWTKPICIGRHAFGDQYRATDTVIKGPGKLKLVFAPSGNEGIKELEVYNFTGAGGIALS 183
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI+ FA+AS A ++K PL+ +TKNTILK YD +FK IF +FD ++ KF+A
Sbjct: 184 MYNTDESIRAFAEASMNFAYQKKWPLYLSTKNTILKKYDGRFKDIFQEVFDTQWNHKFKA 243
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVA LKS GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGK
Sbjct: 244 AGIWYEHRLIDDMVAYALKSDGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGK 303
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+R + R KLD ++ F LE
Sbjct: 304 TIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRPKLDGNARLLDFTEKLEA 363
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN--RSSYVTTEEFIDEVAKRLQNMMLSSNE 412
A + TV++ GKMTKDLAL++ RS Y+ TEEFID VA+ L+ + S ++
Sbjct: 364 ACIGTVEL-GKMTKDLALLVHGPKVSRSQYLNTEEFIDAVAEELRTRLSSQSK 415
>sp|Q5R9C5|IDHC_PONPY Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
Length = 414
Score = 702 bits (1812), Expect = 0.0, Method: Composition-based stats.
Identities = 244/414 (58%), Positives = 311/414 (75%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ +++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVSVETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>gb|AAB39248.1| NADP-isocitrate dehydrogenase [Eucalyptus globulus]
Length = 416
Score = 702 bits (1812), Expect = 0.0, Method: Composition-based stats.
Identities = 257/408 (62%), Positives = 315/408 (77%), Gaps = 3/408 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
KIKV +PIVEMDGDE TRV WK IK+KLI P+L++D+KY+DL + RD T+D+VT +S+
Sbjct: 4 EKIKVENPIVEMDGDEMTRVFWKSIKDKLIFPFLELDIKYFDLGLPHRDATDDKVTIESA 63
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
ATLKY VA+KCATITPDEARMKEF LK+MWKSPNGTIRNIL GTVFREPI+ IPRLV
Sbjct: 64 EATLKYNVAIKCATITPDEARMKEFTLKQMWKSPNGTIRNILNGTVFREPIMCKNIPRLV 123
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHAFGDQY+ATD IK AGKL+L F + E +L+VY F +GG+A++
Sbjct: 124 PGWSKPICIGRHAFGDQYKATDTVIKGAGKLKLVFVPEGTDEKTELEVYNFTGAGGVALS 183
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI+ FA+AS A ++K PL+ +TKNTILK YD +FK IF +++ +K KF+A
Sbjct: 184 MYNTDESIRSFAEASMNTAYQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSKFEA 243
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVA LKS GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGK
Sbjct: 244 AGIWYEHRLIDDMVAYALKSDGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGK 303
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAW+R + R KLDN ++ F LE
Sbjct: 304 TIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRAKLDNNAKLLDFAEKLEA 363
Query: 362 ATLDTVQVGGKMTKDLALMLGKT--NRSSYVTTEEFIDEVAKRLQNMM 407
A + TV+ GKMTKDLAL++ R Y+ TEEFID VA L+ +
Sbjct: 364 ACIGTVE-SGKMTKDLALLIHGPKFTRDQYLNTEEFIDAVAVELKARL 410
>ref|XP_001141655.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 1
[Pan troglodytes]
ref|XP_001141734.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 2
[Pan troglodytes]
ref|XP_001141810.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 3
[Pan troglodytes]
ref|XP_001141879.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 4
[Pan troglodytes]
ref|XP_001141947.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 5
[Pan troglodytes]
ref|XP_001142041.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 6
[Pan troglodytes]
ref|XP_001142113.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 7
[Pan troglodytes]
ref|XP_001142197.1| PREDICTED: isocitrate dehydrogenase 1 (NADP+), soluble isoform 8
[Pan troglodytes]
Length = 414
Score = 702 bits (1812), Expect = 0.0, Method: Composition-based stats.
Identities = 244/414 (58%), Positives = 310/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKRYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F N LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ +++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVSIETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>sp|Q9XSG3|IDHC_BOVIN Isocitrate dehydrogenase [NADP] cytoplasmic (Cytosolic
NADP-isocitrate dehydrogenase) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP)
gb|AAD34457.1|AF136009_1 cytosolic NADP+-dependent isocitrate dehydrogenase [Bos taurus]
Length = 414
Score = 701 bits (1811), Expect = 0.0, Method: Composition-based stats.
Identities = 242/414 (58%), Positives = 306/414 (73%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS+ +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSQKIQGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG V+ F +SGG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEISYTPSDGSPKTVYLVHNFTESGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKNWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSEFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A I YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQNIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ET TN IASIFAWTR + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETLTNPIASIFAWTRGLAHRAKLDNNKELSFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ ++T++ G MTKDLA + RS Y+ T EF+D++ + LQ + +
Sbjct: 361 EVCIETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLQLKLAQAK 413
>emb|CAA53300.1| isocitrate dehydrogenase (NADP+) [Solanum tuberosum]
Length = 438
Score = 701 bits (1811), Expect = 0.0, Method: Composition-based stats.
Identities = 253/413 (61%), Positives = 317/413 (76%), Gaps = 4/413 (0%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
KI V +PIVEMDGDE TRVIWK IK+KLILP+L++D+KY+ L + RD T+D+VT +S+
Sbjct: 26 QKITVQNPIVEMDGDEMTRVIWKSIKDKLILPFLELDIKYFSLGLPHRDATDDKVTVESA 85
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VA+KCATITPDEAR+KEFNLK MW+SPNGTIRNIL GTVFREPI+ IPRLV
Sbjct: 86 EATQKYNVAIKCATITPDEARVKEFNLKSMWRSPNGTIRNILNGTVFREPIMCKNIPRLV 145
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHAFGDQYRATD IK AGKL+L F + E + +VY F +GG+A++
Sbjct: 146 PGWTKPICIGRHAFGDQYRATDTVIKGAGKLKLVFVPEGSDEKTEFEVYNFTGAGGVALS 205
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++S++ FA+AS +A ++K PL+ +TKNTILK YD +FK IF +++ +K K++
Sbjct: 206 MYNTDESVRSFAEASMNMAFQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSKYEE 265
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
I YEHRLIDDMVA LKS+GG++ A KNYDGDVQSD +AQGFGSLGLMTS+L+ PDGK
Sbjct: 266 AGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGK 325
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R HQ+G ETSTNSIASIFAWTR + R LDN + ++ F LE
Sbjct: 326 TIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEKLEA 385
Query: 362 ATLDTVQVGGKMTKDLALML---GKTNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
A + V+ GKMTKDLAL++ K +R Y+ TEEFID VA L+ +L +
Sbjct: 386 ACIGAVE-SGKMTKDLALIIIHGSKLSREHYLNTEEFIDAVADELKARLLKAK 437
>ref|XP_001505172.1| PREDICTED: similar to Isocitrate dehydrogenase [NADP] cytoplasmic
(Cytosolic NADP-isocitrate dehydrogenase)
(Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific
ICDH) (IDP) [Equus caballus]
Length = 414
Score = 701 bits (1809), Expect = 0.0, Method: Composition-based stats.
Identities = 239/414 (57%), Positives = 307/414 (74%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MS+ +VEM GDE TR+IW+LIKEKLI P++++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSQKIRGGSVVEMQGDEMTRIIWELIKEKLIFPHVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A KY V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + G++ + ++ DG + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGRVEITYTPSDGSQKRTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+Y+ +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKSWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYRSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+EAAHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F LE
Sbjct: 301 KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELGFFAKALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 DVCVETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>gb|AAH93020.1| Isocitrate dehydrogenase 1 (NADP+), soluble [Homo sapiens]
Length = 414
Score = 701 bits (1809), Expect = 0.0, Method: Composition-based stats.
Identities = 242/414 (58%), Positives = 311/414 (75%), Gaps = 4/414 (0%)
Query: 1 MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDS 60
MSK +VEM GDE TR+IW+LIKEKLI PY+++DL YDL I+ RD TNDQVTKD+
Sbjct: 1 MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60
Query: 61 SYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRL 120
+ A K+ V VKCATITPDE R++EF LK+MWKSPNGTIRNILGGTVFRE II IPRL
Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120
Query: 121 VPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAM 180
V W KPIIIGRHA+GDQYRATD + GK+ + ++ DG + + V+ F + GG+AM
Sbjct: 121 VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM 180
Query: 181 AMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQ 240
M+N + SI+ FA +SF++AL + PL+ +TKNTILK YD +FK IF ++DK+YK +F+
Sbjct: 181 GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE 240
Query: 241 ALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDG 300
A KI YEHRLIDDMVAQ +KS+GGFI A KNYDGDVQSD VAQG+GSLG+MTS+L+ PDG
Sbjct: 241 AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG 300
Query: 301 KTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLE 360
KT E+E+AHGTVTRH+R +Q+G+ETSTN IASIFAWTR + R KLDN ++ F N LE
Sbjct: 301 KTVEAESAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE 360
Query: 361 KATLDTVQVGGKMTKDLALMLGK---TNRSSYVTTEEFIDEVAKRLQNMMLSSN 411
+ +++T++ G MTKDLA + RS Y+ T EF+D++ + L+ + +
Sbjct: 361 EVSIETIEA-GFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAK 413
>gb|EAX02083.1| isocitrate dehydrogenase 2 (NADP+), mitochondrial, isoform CRA_b
[Homo sapiens]
Length = 422
Score = 701 bits (1809), Expect = 0.0, Method: Composition-based stats.
Identities = 251/413 (60%), Positives = 311/413 (75%), Gaps = 6/413 (1%)
Query: 2 SKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSS 61
+IKV P+VEMDGDE TR+IW+ IKEKLILP++D+ LKY+DL + RD+T+DQVT DS+
Sbjct: 12 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSA 71
Query: 62 YATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLV 121
AT KY VAVKCATITPDEAR++EF LK+MWKSPNGTIRNILGGTVFREPII IPRLV
Sbjct: 72 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 131
Query: 122 PHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMA 181
P W KPI IGRHA GDQY+ATD +AG ++ F+ DG + +VY FP +GG+ M
Sbjct: 132 PGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMG 190
Query: 182 MFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQA 241
M+NT++SI GFA + F+ A+++K PL+ +TKNTILK YD +FK IF +FDK YK F
Sbjct: 191 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDK 250
Query: 242 LKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGK 301
KI YEHRLIDDMVAQ+LKS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+L+ PDGK
Sbjct: 251 NKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGK 310
Query: 302 TFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEK 361
T E+EAAHGTVTRH+R+HQ+G TSTN IASIFAWTR + RGKLD D+I+F +LEK
Sbjct: 311 TIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEK 370
Query: 362 ATLDTVQVGGKMTKDLALMLGKTN----RSSYVTTEEFIDEVAKRLQNMMLSS 410
++TV+ G MTKDLA + + ++ T +F+D + L +
Sbjct: 371 VCVETVE-SGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 422
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
Posted date: May 23, 2008 5:56 PM
Number of letters in database: 883,778,997
Number of sequences in database: 2,617,685
Database: /host/Blast/data/nr_perl/nr.01
Posted date: May 23, 2008 5:54 PM
Number of letters in database: 976,759,346
Number of sequences in database: 2,761,413
Database: /host/Blast/data/nr_perl/nr.02
Posted date: May 23, 2008 5:48 PM
Number of letters in database: 374,670,760
Number of sequences in database: 1,165,270
Database: /host/Blast/data/nr_perl/nr.03
Posted date: Apr 28, 2009 5:40 PM
Number of letters in database: 114,943,120
Number of sequences in database: 354,819
Lambda K H
0.315 0.170 0.516
Lambda K H
0.267 0.0521 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,363,047,224
Number of Sequences: 6899187
Number of extensions: 402883310
Number of successful extensions: 918004
Number of sequences better than 10.0: 300
Number of HSP's better than 10.0 without gapping: 6789
Number of HSP's successfully gapped in prelim test: 2077
Number of HSP's that attempted gapping in prelim test: 876577
Number of HSP's gapped (non-prelim): 9899
length of query: 420
length of database: 2,350,152,223
effective HSP length: 137
effective length of query: 283
effective length of database: 1,404,963,604
effective search space: 397604699932
effective search space used: 397604699932
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 81 (35.5 bits)