BLASTP 2.2.17 [Aug-26-2007]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden, 
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= YOR193W__[Saccharomyces_cerevisiae]
         (376 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           6,899,187 sequences; 2,350,152,223 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|NP_014836.1|  Peripheral peroxisomal membrane protein in...   654   0.0  
gb|EDN63529.1|  peroxisome-related protein [Saccharomyces ce...   645   0.0  
ref|NP_015213.1|  Peripheral peroxisomal membrane peroxin re...    56   6e-06
gb|AAT92840.1|  YPL112C [Saccharomyces cerevisiae]                 55   6e-06
gb|EDN61031.1|  peroxin [Saccharomyces cerevisiae YJM789]          55   1e-05
ref|NP_986892.1|  AGR226Wp [Ashbya gossypii ATCC 10895] >gi|...    46   0.004
ref|XP_455112.1|  unnamed protein product [Kluyveromyces lac...    44   0.031
ref|XP_447712.1|  hypothetical protein CAGL0I10879g [Candida...    39   0.93 
ref|YP_001124388.1|  Amine oxidase, flavin-containing [Geoba...    37   1.7  
ref|ZP_02864695.1|  hypothetical protein CPC_2278 [Clostridi...    35   7.5  
>ref|NP_014836.1| Peripheral peroxisomal membrane protein involved in controlling
           peroxisome size and number, interacts with homologous
           protein Pex25p; Pex27p [Saccharomyces cerevisiae]
 sp|Q08580|PEX27_YEAST Peroxisomal membrane protein PEX27 (Peroxin-27)
 emb|CAA99406.1| unnamed protein product [Saccharomyces cerevisiae]
 gb|AAU09786.1| YOR193W [Saccharomyces cerevisiae]
          Length = 376

 Score =  654 bits (1688), Expect = 0.0,   Method: Composition-based stats.
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI 60
           MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI
Sbjct: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI 60

Query: 61  VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120
           VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE
Sbjct: 61  VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120

Query: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180
           VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR
Sbjct: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180

Query: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240
           FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT
Sbjct: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240

Query: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP 300
           NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP
Sbjct: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP 300

Query: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL 360
           TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL
Sbjct: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL 360

Query: 361 WNRAKVTSANEHTSAV 376
           WNRAKVTSANEHTSAV
Sbjct: 361 WNRAKVTSANEHTSAV 376
>gb|EDN63529.1| peroxisome-related protein [Saccharomyces cerevisiae YJM789]
          Length = 376

 Score =  645 bits (1664), Expect = 0.0,   Method: Composition-based stats.
 Identities = 371/376 (98%), Positives = 374/376 (99%)

Query: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI 60
           MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKG IAKKPI
Sbjct: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGEIAKKPI 60

Query: 61  VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120
           VLQDNDDSDFTQNQGKVATATSTT+DRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE
Sbjct: 61  VLQDNDDSDFTQNQGKVATATSTTNDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120

Query: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180
           VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR
Sbjct: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180

Query: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240
           FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT
Sbjct: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240

Query: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP 300
           NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKE+ELKYKLP
Sbjct: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEHELKYKLP 300

Query: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL 360
           TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYN ELAYEIISVGSGVTELLKL
Sbjct: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNLELAYEIISVGSGVTELLKL 360

Query: 361 WNRAKVTSANEHTSAV 376
           WN+AKVTSANEHTSAV
Sbjct: 361 WNQAKVTSANEHTSAV 376
>ref|NP_015213.1| Peripheral peroxisomal membrane peroxin required for the regulation
           of peroxisome size and maintenance, recruits GTPase
           Rho1p to peroxisomes, induced by oleate, interacts with
           homologous protein Pex27p; Pex25p [Saccharomyces
           cerevisiae]
 sp|Q02969|PEX25_YEAST Peroxisomal membrane protein PEX25 (Peroxin-25)
 gb|AAB68249.1| Ypl112cp [Saccharomyces cerevisiae]
          Length = 394

 Score = 55.8 bits (133), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 62/273 (22%), Positives = 121/273 (44%), Gaps = 54/273 (19%)

Query: 126 LQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLR 185
           L+H + ++ +LLL+    L NF  K+  + QQLS FRY LRFG     +   + +F    
Sbjct: 135 LRHPITVIKVLLLSL---LRNFDKKIDFISQQLSTFRYILRFGGTPFRVCSFLGKF---N 188

Query: 186 EMKKLHYK-DQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLM 244
           + +K +++ DQ    +F      + ++ +Y + DEL L +KL+    K            
Sbjct: 189 KTRKCNFQIDQIKKIWFNEASLREFLDLYYGIFDELDLLYKLKIWTNKS---------FY 239

Query: 245 TFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAI------------- 290
           +FV  Q  + W+   +L++  +    + L + ++ L +      NA+             
Sbjct: 240 SFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQLELEVQLKVQNNALLLSPILMHQAHKD 299

Query: 291 --KEYELKYKLPTNDKVN-------------LELRKNNITLDFYKIILNLLSN---LINI 332
              +  ++ +L  +  VN             ++  K  + LD  ++  + ++N   ++N+
Sbjct: 300 DGSQSPIRKQLLNDLNVNNDAEVLIHKQLKAIKDEKTLVYLDIARLSFDCMANTSDILNL 359

Query: 333 KGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
           K  +        Y ++S+GSG+T L+KLW   K
Sbjct: 360 KTPKG------TYAVLSLGSGLTGLVKLWITTK 386
>gb|AAT92840.1| YPL112C [Saccharomyces cerevisiae]
          Length = 394

 Score = 55.5 bits (132), Expect = 6e-06,   Method: Composition-based stats.
 Identities = 62/273 (22%), Positives = 121/273 (44%), Gaps = 54/273 (19%)

Query: 126 LQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLR 185
           L+H + ++ +LLL+    L NF  K+  + QQLS FRY LRFG     +   + +F    
Sbjct: 135 LRHPITVIKVLLLSL---LRNFDKKIDFISQQLSTFRYILRFGGTPFRVCSFLGKF---N 188

Query: 186 EMKKLHYK-DQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLM 244
           + +K +++ DQ    +F      + ++ +Y + DEL L +KL+    K            
Sbjct: 189 KTRKCNFQIDQIKKIWFNEASLREFLDLYYGIFDELDLLYKLKIWTNKS---------FY 239

Query: 245 TFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAI------------- 290
           +FV  Q  + W+   +L++  +    + L + ++ L +      NA+             
Sbjct: 240 SFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQLELEVQLKVQNNALLLSPILMHQAHKD 299

Query: 291 --KEYELKYKLPTNDKVN-------------LELRKNNITLDFYKIILNLLSN---LINI 332
              +  ++ +L  +  VN             ++  K  + LD  ++  + ++N   ++N+
Sbjct: 300 DGSQSPIRKQLLNDLNVNNDAEVLIHKQLKAIKDEKTLVYLDIARLSFDCMANTSDILNL 359

Query: 333 KGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
           K  +        Y ++S+GSG+T L+KLW   K
Sbjct: 360 KTPKG------TYAVLSLGSGLTGLVKLWITTK 386
>gb|EDN61031.1| peroxin [Saccharomyces cerevisiae YJM789]
          Length = 394

 Score = 54.7 bits (130), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 62/273 (22%), Positives = 118/273 (43%), Gaps = 54/273 (19%)

Query: 126 LQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLR 185
           L+H + ++ +LLL+    L NF  K+  + QQLS FRY LRFG     +   + +F    
Sbjct: 135 LRHPITVIKVLLLSL---LRNFDKKIDFISQQLSTFRYILRFGGTPFRVCSFLGKF---N 188

Query: 186 EMKKLHYK-DQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLM 244
           + +K +++ DQ    +F      + ++ +Y + DEL L +KL+    K            
Sbjct: 189 KTRKCNFQIDQIKKIWFDEASLREFLDLYYGIFDELDLLYKLKIWTNKS---------FY 239

Query: 245 TFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE-LKYKLPTN 302
           +FV  Q  + W+   +L++  +    + L + ++ L +      NA+     L ++   +
Sbjct: 240 SFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQLELEVQLKVQNNALLLSPILMHQAHKD 299

Query: 303 DKVNLELRKNN---------------------------ITLDFYKIILNLLSN---LINI 332
           D     +RK                             + LD  ++  + ++N   ++N+
Sbjct: 300 DGSQSPIRKQLLNDLNVNNNAEVLIHKQLKAIKDEKTLVYLDIARLSFDCMANTSDILNL 359

Query: 333 KGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
           K  +        Y ++S+GSG+T L+KLW   K
Sbjct: 360 KTPKG------TYAVLSLGSGLTGLVKLWITTK 386
>ref|NP_986892.1| AGR226Wp [Ashbya gossypii ATCC 10895]
 gb|AAS54716.1| AGR226Wp [Ashbya gossypii ATCC 10895]
          Length = 323

 Score = 46.2 bits (108), Expect = 0.004,   Method: Composition-based stats.
 Identities = 66/302 (21%), Positives = 129/302 (42%), Gaps = 50/302 (16%)

Query: 97  EMKKRYVKKNCQAKFVFNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQ 156
           + + R V+ +  A   +  L G      +++H + LL L L++   +   F +K + V  
Sbjct: 34  QYRTRLVQSDPTALARYARLAGAWSWGLLVRHPVTLLKLWLVSVAKQ---FEAKSQTVCT 90

Query: 157 QLSLFRYYLRFGN---FAINLYKIIKRFRWLREMKKLHYKDQSILF------YFKNFRFF 207
            +S+FR  +RFG+    A  LY+  K     R+ +KL   D + +       +       
Sbjct: 91  NISIFRQMMRFGSTPFLARALYQ--KAAATYRQAQKLPAGDTAGVLQVVRGQWLNEPTLT 148

Query: 208 DIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNI 267
           D++  +Y + DEL L +    ++  K         L  FV     + W+   +L++ K  
Sbjct: 149 DVLYLYYGIMDELSLTYSF-GLWAHKG--------LYAFVARHEVLSWQYDILLSLKKGW 199

Query: 268 EQWRQL------------IRD---EIYLSIYNTSGNAIKEYELKYKL---PTNDKV---- 305
            + R++            +R    +I   +++  G +  + +L   L   PT+D      
Sbjct: 200 CRLREINAKILDLEIQCKVRQRAWDISQKLHSARGTSPVKRQLLRDLQLGPTSDMSLTAD 259

Query: 306 --NLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKLWNR 363
              L   ++ + +DF ++  +LL+N  ++   R    +   Y  +S+GSG+    KLW +
Sbjct: 260 LDALRQERSVLYVDFVRLTFDLLANSTDVFALRTPPGT---YAWLSLGSGMAGFYKLWTQ 316

Query: 364 AK 365
           AK
Sbjct: 317 AK 318
>ref|XP_455112.1| unnamed protein product [Kluyveromyces lactis]
 emb|CAG97819.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
          Length = 431

 Score = 43.5 bits (101), Expect = 0.031,   Method: Composition-based stats.
 Identities = 76/332 (22%), Positives = 128/332 (38%), Gaps = 91/332 (27%)

Query: 110 KFVFNTLEGKEVCSKILQHTLGLL---------------------------SLLLLTRKI 142
           K VF TL GK+  +KI ++ + +L                           +LL + R  
Sbjct: 110 KAVFATLTGKDRIAKIFKYVIDILRIFIQRSMYYNNKDIDVDAYLKLFSKGNLLTILRNP 169

Query: 143 RL-----LNFSSKL-----RLVIQQLSLFRYYLRFGNFAINLY----KIIKRFRWLREMK 188
           RL     L+ SSKL      LV  QL  +R  +R G     LY    K+I  F   ++  
Sbjct: 170 RLSGKLFLSSSSKLFLEKGALVSSQLGFYRQIMRCGGTPFRLYHWYQKLISTFYASQKSS 229

Query: 189 KLHYKDQSILFYFKNF----RFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLM 244
            LH K    L ++KN+       + I+ +Y + DEL+L +KL+    K          + 
Sbjct: 230 TLHSKG---LVWYKNWWNEESLSEFIDLYYGIMDELMLLYKLKLWSNKS---------MH 277

Query: 245 TFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIY--------------------- 283
            +V +   + W    +L + KN E+ + + + E  L I                      
Sbjct: 278 AWVSKHEALSWYYDIMLGLKKNWEKLQSIKQQEFELKIQYQVRQRALELSSKLNATPSVD 337

Query: 284 ---------NTSGNAIKEYELKYKLPTNDKV-NLELRKNNITLDFYKIILNLLSNLINIK 333
                     T   + K+  L  +L    K+ N +  K  +  D  ++  + L++  ++ 
Sbjct: 338 SNKNTALIKQTIFESFKQDNLDLELEVVQKLKNYQYEKRIVKFDLTRLFFDFLADTTDVF 397

Query: 334 GKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
             +    +   Y I+S+ SGV    KLW +AK
Sbjct: 398 SIKTPPGT---YAILSLCSGVLGFSKLWIQAK 426
>ref|XP_447712.1| hypothetical protein CAGL0I10879g [Candida glabrata CBS138]
 emb|CAG60657.1| unnamed protein product [Candida glabrata CBS 138]
          Length = 363

 Score = 38.5 bits (88), Expect = 0.93,   Method: Composition-based stats.
 Identities = 53/250 (21%), Positives = 107/250 (42%), Gaps = 44/250 (17%)

Query: 146 NFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLREMKKLHYKDQSI-LFYFKNF 204
           NF  K   + QQLS +RY LRFG+    +  I K+   L +  K       I   +F   
Sbjct: 122 NFEIKASYLSQQLSTYRYILRFGSSPFQVLNIWKK---LAQTYKEGLTASCIHKLWFNED 178

Query: 205 RFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAIN 264
              ++I     + DEL+L +KL+    K             ++++Q  I WE   + ++ 
Sbjct: 179 SIREVINLHNTVCDELVLLYKLKVWDHKD---------FYNWLEKQEAISWEADILFSLK 229

Query: 265 KNIEQWRQLIRD---------------EIYLSIYNTSGNAIKEY-ELKYKLPTND---KV 305
             + + +++ +                E+  S++ +  N    + +L ++   +D   + 
Sbjct: 230 NKLIELQEMKQKRYEMLIDLRARRQALELSKSLHRSRENMSPIHNQLLHEFDNSDDWRRT 289

Query: 306 NLELRK---------NNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTE 356
            LE+           + I LD  ++  +L++N  ++   R    +   Y + S+GSG++ 
Sbjct: 290 ELEISSQLEEYRHGISMIYLDIMRLSCDLIANTTDVLNMRVPRGT---YAVFSLGSGLSG 346

Query: 357 LLKLWNRAKV 366
           L+KLW+  ++
Sbjct: 347 LMKLWHTTRM 356
>ref|YP_001124388.1| Amine oxidase, flavin-containing [Geobacillus thermodenitrificans
           NG80-2]
 gb|ABO65643.1| Amine oxidase, flavin-containing [Geobacillus thermodenitrificans
           NG80-2]
          Length = 480

 Score = 37.4 bits (85), Expect = 1.7,   Method: Composition-based stats.
 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 19/111 (17%)

Query: 153 LVIQQLSLFRY--YLRFGNF-------AINLYKIIKRFRWLREMKKLHYKDQSILFYFKN 203
           +VI+QL  + +  YLR+  F       AI++ K +       E+  L    + +  +  N
Sbjct: 164 IVIEQLDRYSFDTYLRYNPFGLRLSVGAIDMIKAVLSLEGFPELSFLGLLRELMTLFTPN 223

Query: 204 FRFFDII-------EAFY-NLTDELILFHKLQSMFGKKN--TSHANTNRLM 244
            RF+ I+       +AF   L DEL+  HK+Q +   KN  T HA   +++
Sbjct: 224 MRFYKIVGGNDRLPKAFLPQLKDELLFSHKVQKIVQNKNSVTIHAIHTKIL 274
>ref|ZP_02864695.1| hypothetical protein CPC_2278 [Clostridium perfringens C str.
           JGS1495]
 gb|EDS80346.1| hypothetical protein CPC_2278 [Clostridium perfringens C str.
           JGS1495]
          Length = 392

 Score = 35.4 bits (80), Expect = 7.5,   Method: Composition-based stats.
 Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 9/125 (7%)

Query: 205 RFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAIN 264
           +F DI  +   L D  ++F+K + +FG++ T  A T      + E+ +   +VL      
Sbjct: 33  KFKDIYGSRSELGDVDLVFYKDRDIFGEEITVGAETINRKNVINERRFDGIDVLKDKKFF 92

Query: 265 KNIEQWRQLI--RDEIYLSIYNTSGNAIKEYELKYKLPTND-------KVNLELRKNNIT 315
           + I Q R      D++ + + N  GN I++ E+++K    +       KV+  +R NNI 
Sbjct: 93  RGIYQTRDTFFEDDDVMVDVTNIYGNGIQKLEVRFKDKKTNTYETFKVKVDEYIRNNNID 152

Query: 316 LDFYK 320
              YK
Sbjct: 153 KVTYK 157
Searching..................................................done Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

gb|EDN63529.1|  peroxisome-related protein [Saccharomyces ce...   618   e-175
ref|NP_014836.1|  Peripheral peroxisomal membrane protein in...   618   e-175
gb|EDN61031.1|  peroxin [Saccharomyces cerevisiae YJM789]         317   1e-84
ref|NP_015213.1|  Peripheral peroxisomal membrane peroxin re...   314   9e-84
gb|AAT92840.1|  YPL112C [Saccharomyces cerevisiae]                313   1e-83
Sequences not found previously or not previously below threshold:

ref|XP_447712.1|  hypothetical protein CAGL0I10879g [Candida...   147   2e-33
ref|NP_986892.1|  AGR226Wp [Ashbya gossypii ATCC 10895] >gi|...   138   1e-30
ref|XP_455112.1|  unnamed protein product [Kluyveromyces lac...   137   1e-30
ref|XP_001646454.1|  hypothetical protein Kpol_1048p26 [Vand...   128   9e-28
ref|XP_719137.1|  peroxisome regulatory protein Pex25 [Candi...    82   6e-14
ref|XP_719254.1|  peroxisome regulatory protein Pex25 [Candi...    82   7e-14
ref|XP_001383435.2|  hypothetical protein PICST_56779 [Pichi...    79   6e-13
ref|XP_457136.1|  hypothetical protein DEHA0B03894g [Debaryo...    72   1e-10
gb|ABG36525.1|  Pex25p [Pichia angusta]                            68   1e-09
ref|XP_001523976.1|  conserved hypothetical protein [Loddero...    66   5e-09
ref|XP_001485441.1|  hypothetical protein PGUG_03169 [Pichia...    59   7e-07
ref|NP_345727.1|  DNA topoisomerase I [Streptococcus pneumon...    40   0.43 
ref|NP_358734.1|  DNA topoisomerase I [Streptococcus pneumon...    40   0.45 
ref|ZP_01407769.1|  hypothetical protein SpneT_02001810 [Str...    40   0.45 
ref|YP_816589.1|  DNA topoisomerase I [Streptococcus pneumon...    40   0.45 
ref|ZP_01824014.1|  DNA topoisomerase I [Streptococcus pneum...    40   0.46 
ref|ZP_02717324.1|  DNA topoisomerase I [Streptococcus pneum...    40   0.47 
ref|ZP_01818400.1|  DNA topoisomerase I [Streptococcus pneum...    39   0.67 
ref|YP_001040065.1|  serine proteases-like protein [Staphylo...    38   1.5  
ref|ZP_01830742.1|  DNA topoisomerase I [Streptococcus pneum...    37   1.9  
ref|ZP_01820667.1|  DNA topoisomerase I [Streptococcus pneum...    37   2.0  
ref|YP_001835757.1|  DNA topoisomerase I [Streptococcus pneu...    37   2.0  
ref|YP_002738435.1|  DNA topoisomerase I [Streptococcus pneu...    37   2.0  
ref|ZP_01834618.1|  DNA topoisomerase I [Streptococcus pneum...    37   2.0  
ref|ZP_02715323.1|  DNA topoisomerase I [Streptococcus pneum...    37   2.0  
ref|YP_002740567.1|  DNA topoisomerase I [Streptococcus pneu...    37   2.0  
ref|NP_612284.1|  ORF062L [Infectious spleen and kidney necr...    37   3.2  
ref|XP_449653.1|  hypothetical protein CAGL0M07029g [Candida...    37   3.4  
ref|ZP_00366966.1|  conserved hypothetical integral membrane...    36   4.0  
ref|XP_001524758.1|  hypothetical protein LELG_03790 [Lodder...    36   4.1  
gb|AAT71873.1|  putative DNA-binding protein [Rock bream iri...    36   4.2  
gb|AAX82370.1|  ORF61L [Orange-spotted grouper iridovirus]         36   4.6  
ref|ZP_01826136.1|  DNA topoisomerase I [Streptococcus pneum...    36   5.2  
ref|NP_845093.1|  hypothetical protein BA2743 [Bacillus anth...    35   8.5  
ref|ZP_02213167.1|  conserved hypothetical protein [Bacillus...    35   9.0  
ref|YP_001802698.1|  UPF0004-containing protein [Cyanothece ...    35   9.6  
>gb|EDN63529.1| peroxisome-related protein [Saccharomyces cerevisiae YJM789]
          Length = 376

 Score =  618 bits (1593), Expect = e-175,   Method: Composition-based stats.
 Identities = 371/376 (98%), Positives = 374/376 (99%)

Query: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI 60
           MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKG IAKKPI
Sbjct: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGEIAKKPI 60

Query: 61  VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120
           VLQDNDDSDFTQNQGKVATATSTT+DRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE
Sbjct: 61  VLQDNDDSDFTQNQGKVATATSTTNDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120

Query: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180
           VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR
Sbjct: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180

Query: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240
           FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT
Sbjct: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240

Query: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP 300
           NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKE+ELKYKLP
Sbjct: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEHELKYKLP 300

Query: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL 360
           TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYN ELAYEIISVGSGVTELLKL
Sbjct: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNLELAYEIISVGSGVTELLKL 360

Query: 361 WNRAKVTSANEHTSAV 376
           WN+AKVTSANEHTSAV
Sbjct: 361 WNQAKVTSANEHTSAV 376
>ref|NP_014836.1| Peripheral peroxisomal membrane protein involved in controlling
           peroxisome size and number, interacts with homologous
           protein Pex25p; Pex27p [Saccharomyces cerevisiae]
 sp|Q08580|PEX27_YEAST Peroxisomal membrane protein PEX27 (Peroxin-27)
 emb|CAA99406.1| unnamed protein product [Saccharomyces cerevisiae]
 gb|AAU09786.1| YOR193W [Saccharomyces cerevisiae]
          Length = 376

 Score =  618 bits (1593), Expect = e-175,   Method: Composition-based stats.
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI 60
           MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI
Sbjct: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI 60

Query: 61  VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120
           VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE
Sbjct: 61  VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120

Query: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180
           VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR
Sbjct: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180

Query: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240
           FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT
Sbjct: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240

Query: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP 300
           NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP
Sbjct: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP 300

Query: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL 360
           TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL
Sbjct: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL 360

Query: 361 WNRAKVTSANEHTSAV 376
           WNRAKVTSANEHTSAV
Sbjct: 361 WNRAKVTSANEHTSAV 376
>gb|EDN61031.1| peroxin [Saccharomyces cerevisiae YJM789]
          Length = 394

 Score =  317 bits (812), Expect = 1e-84,   Method: Composition-based stats.
 Identities = 62/273 (22%), Positives = 118/273 (43%), Gaps = 54/273 (19%)

Query: 126 LQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLR 185
           L+H + ++ +LLL+    L NF  K+  + QQLS FRY LRFG     +   + +F    
Sbjct: 135 LRHPITVIKVLLLSL---LRNFDKKIDFISQQLSTFRYILRFGGTPFRVCSFLGKF---N 188

Query: 186 EMKKLHYK-DQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLM 244
           + +K +++ DQ    +F      + ++ +Y + DEL L +KL+    K            
Sbjct: 189 KTRKCNFQIDQIKKIWFDEASLREFLDLYYGIFDELDLLYKLKIWTNKS---------FY 239

Query: 245 TFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE-LKYKLPTN 302
           +FV  Q  + W+   +L++  +    + L + ++ L +      NA+     L ++   +
Sbjct: 240 SFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQLELEVQLKVQNNALLLSPILMHQAHKD 299

Query: 303 DKVNLELRKN---------------------------NITLDFYKIILNLLSN---LINI 332
           D     +RK                             + LD  ++  + ++N   ++N+
Sbjct: 300 DGSQSPIRKQLLNDLNVNNNAEVLIHKQLKAIKDEKTLVYLDIARLSFDCMANTSDILNL 359

Query: 333 KGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
           K  +        Y ++S+GSG+T L+KLW   K
Sbjct: 360 KTPKG------TYAVLSLGSGLTGLVKLWITTK 386
>ref|NP_015213.1| Peripheral peroxisomal membrane peroxin required for the regulation
           of peroxisome size and maintenance, recruits GTPase
           Rho1p to peroxisomes, induced by oleate, interacts with
           homologous protein Pex27p; Pex25p [Saccharomyces
           cerevisiae]
 sp|Q02969|PEX25_YEAST Peroxisomal membrane protein PEX25 (Peroxin-25)
 gb|AAB68249.1| Ypl112cp [Saccharomyces cerevisiae]
          Length = 394

 Score =  314 bits (804), Expect = 9e-84,   Method: Composition-based stats.
 Identities = 62/273 (22%), Positives = 118/273 (43%), Gaps = 54/273 (19%)

Query: 126 LQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLR 185
           L+H + ++ +LLL+    L NF  K+  + QQLS FRY LRFG     +   + +F    
Sbjct: 135 LRHPITVIKVLLLSL---LRNFDKKIDFISQQLSTFRYILRFGGTPFRVCSFLGKF---N 188

Query: 186 EMKKLHYK-DQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLM 244
           + +K +++ DQ    +F      + ++ +Y + DEL L +KL+    K            
Sbjct: 189 KTRKCNFQIDQIKKIWFNEASLREFLDLYYGIFDELDLLYKLKIWTNKS---------FY 239

Query: 245 TFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE-LKYKLPTN 302
           +FV  Q  + W+   +L++  +    + L + ++ L +      NA+     L ++   +
Sbjct: 240 SFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQLELEVQLKVQNNALLLSPILMHQAHKD 299

Query: 303 DKVNLELRKN---------------------------NITLDFYKIILNLLSN---LINI 332
           D     +RK                             + LD  ++  + ++N   ++N+
Sbjct: 300 DGSQSPIRKQLLNDLNVNNDAEVLIHKQLKAIKDEKTLVYLDIARLSFDCMANTSDILNL 359

Query: 333 KGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
           K  +        Y ++S+GSG+T L+KLW   K
Sbjct: 360 KTPKG------TYAVLSLGSGLTGLVKLWITTK 386
>gb|AAT92840.1| YPL112C [Saccharomyces cerevisiae]
          Length = 394

 Score =  313 bits (803), Expect = 1e-83,   Method: Composition-based stats.
 Identities = 62/273 (22%), Positives = 118/273 (43%), Gaps = 54/273 (19%)

Query: 126 LQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLR 185
           L+H + ++ +LLL+    L NF  K+  + QQLS FRY LRFG     +   + +F    
Sbjct: 135 LRHPITVIKVLLLSL---LRNFDKKIDFISQQLSTFRYILRFGGTPFRVCSFLGKF---N 188

Query: 186 EMKKLHYK-DQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLM 244
           + +K +++ DQ    +F      + ++ +Y + DEL L +KL+    K            
Sbjct: 189 KTRKCNFQIDQIKKIWFNEASLREFLDLYYGIFDELDLLYKLKIWTNKS---------FY 239

Query: 245 TFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE-LKYKLPTN 302
           +FV  Q  + W+   +L++  +    + L + ++ L +      NA+     L ++   +
Sbjct: 240 SFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQLELEVQLKVQNNALLLSPILMHQAHKD 299

Query: 303 DKVNLELRKN---------------------------NITLDFYKIILNLLSN---LINI 332
           D     +RK                             + LD  ++  + ++N   ++N+
Sbjct: 300 DGSQSPIRKQLLNDLNVNNDAEVLIHKQLKAIKDEKTLVYLDIARLSFDCMANTSDILNL 359

Query: 333 KGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
           K  +        Y ++S+GSG+T L+KLW   K
Sbjct: 360 KTPKG------TYAVLSLGSGLTGLVKLWITTK 386
>ref|XP_447712.1| hypothetical protein CAGL0I10879g [Candida glabrata CBS138]
 emb|CAG60657.1| unnamed protein product [Candida glabrata CBS 138]
          Length = 363

 Score =  147 bits (371), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 51/276 (18%), Positives = 112/276 (40%), Gaps = 57/276 (20%)

Query: 125 ILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWL 184
           +L+H + +  + ++       NF  K   + QQLS +RY LRFG+    +  I K+    
Sbjct: 104 MLRHPITIAKIWVVAMS---RNFEIKASYLSQQLSTYRYILRFGSSPFQVLNIWKKLAQT 160

Query: 185 RE---MKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTN 241
            +                +F      ++I     + DEL+L +KL+    K         
Sbjct: 161 YKEGLTASC-----IHKLWFNEDSIREVINLHNTVCDELVLLYKLKVWDHK--------- 206

Query: 242 RLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKE-------- 292
               ++++Q  I WE   + ++   + + +++ +    + I       A++         
Sbjct: 207 DFYNWLEKQEAISWEADILFSLKNKLIELQEMKQKRYEMLIDLRARRQALELSKSLHRSR 266

Query: 293 ---YELKYKLP-----------TNDKVNLELRK-----NNITLDFYKIILNLLSN---LI 330
                +  +L            T  +++ +L +     + I LD  ++  +L++N   ++
Sbjct: 267 ENMSPIHNQLLHEFDNSDDWRRTELEISSQLEEYRHGISMIYLDIMRLSCDLIANTTDVL 326

Query: 331 NIKGKRDKYNSELAYEIISVGSGVTELLKLWNRAKV 366
           N++  R        Y + S+GSG++ L+KLW+  ++
Sbjct: 327 NMRVPRG------TYAVFSLGSGLSGLMKLWHTTRM 356
>ref|NP_986892.1| AGR226Wp [Ashbya gossypii ATCC 10895]
 gb|AAS54716.1| AGR226Wp [Ashbya gossypii ATCC 10895]
          Length = 323

 Score =  138 bits (347), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 59/303 (19%), Positives = 119/303 (39%), Gaps = 52/303 (17%)

Query: 97  EMKKRYVKKNCQAKFVFNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQ 156
           + + R V+ +  A   +  L G      +++H + LL L L++       F +K + V  
Sbjct: 34  QYRTRLVQSDPTALARYARLAGAWSWGLLVRHPVTLLKLWLVSVA---KQFEAKSQTVCT 90

Query: 157 QLSLFRYYLRFGNFAINLYKIIKRFRWL-REMKKLHYKDQSILF------YFKNFRFFDI 209
            +S+FR  +RFG+       + ++     R+ +KL   D + +       +       D+
Sbjct: 91  NISIFRQMMRFGSTPFLARALYQKAAATYRQAQKLPAGDTAGVLQVVRGQWLNEPTLTDV 150

Query: 210 IEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQ 269
           +  +Y + DEL L +       K          L  FV     + W+   +L++ K   +
Sbjct: 151 LYLYYGIMDELSLTYSFGLWAHK---------GLYAFVARHEVLSWQYDILLSLKKGWCR 201

Query: 270 WRQLIRDEIYLSI-YNTSGNA--IKE--------YELKYKLPTNDKVN------------ 306
            R++    + L I       A  I +          +K +L  + ++             
Sbjct: 202 LREINAKILDLEIQCKVRQRAWDISQKLHSARGTSPVKRQLLRDLQLGPTSDMSLTADLD 261

Query: 307 -LELRKNNITLDFYKIILNLLSN---LINIKGKRDKYNSELAYEIISVGSGVTELLKLWN 362
            L   ++ + +DF ++  +LL+N   +  ++           Y  +S+GSG+    KLW 
Sbjct: 262 ALRQERSVLYVDFVRLTFDLLANSTDVFALRTPPG------TYAWLSLGSGMAGFYKLWT 315

Query: 363 RAK 365
           +AK
Sbjct: 316 QAK 318
>ref|XP_455112.1| unnamed protein product [Kluyveromyces lactis]
 emb|CAG97819.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
          Length = 431

 Score =  137 bits (346), Expect = 1e-30,   Method: Composition-based stats.
 Identities = 64/280 (22%), Positives = 107/280 (38%), Gaps = 57/280 (20%)

Query: 125 ILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLY----KIIKR 180
           IL++   L   L L+   +L  F  K  LV  QL  +R  +R G     LY    K+I  
Sbjct: 165 ILRNP-RLSGKLFLSSSSKL--FLEKGALVSSQLGFYRQIMRCGGTPFRLYHWYQKLIST 221

Query: 181 FRWLREMKKLHYKDQS-ILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHAN 239
           F   ++   LH K       ++      + I+ +Y + DEL+L +KL+    K       
Sbjct: 222 FYASQKSSTLHSKGLVWYKNWWNEESLSEFIDLYYGIMDELMLLYKLKLWSNKS------ 275

Query: 240 TNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYELKYK 298
              +  +V +   + W    +L + KN E+ + + + E  L I Y     A++       
Sbjct: 276 ---MHAWVSKHEALSWYYDIMLGLKKNWEKLQSIKQQEFELKIQYQVRQRALELSSKLNA 332

Query: 299 LP-------------------TNDKVNLEL-----------RKNNITLDFYKIILNLLS- 327
            P                     D ++LEL            K  +  D  ++  + L+ 
Sbjct: 333 TPSVDSNKNTALIKQTIFESFKQDNLDLELEVVQKLKNYQYEKRIVKFDLTRLFFDFLAD 392

Query: 328 --NLINIKGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
             ++ +IK           Y I+S+ SGV    KLW +AK
Sbjct: 393 TTDVFSIKTPPG------TYAILSLCSGVLGFSKLWIQAK 426
>ref|XP_001646454.1| hypothetical protein Kpol_1048p26 [Vanderwaltozyma polyspora DSM
           70294]
 gb|EDO18596.1| hypothetical protein Kpol_1048p26 [Vanderwaltozyma polyspora DSM
           70294]
          Length = 418

 Score =  128 bits (321), Expect = 9e-28,   Method: Composition-based stats.
 Identities = 54/300 (18%), Positives = 101/300 (33%), Gaps = 70/300 (23%)

Query: 113 FNTLEGKEVCSK-ILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFA 171
           FN L+G     K  ++  L  +   L+       +   K+  +  QLS FRY LRFG   
Sbjct: 136 FNKLKGNYSLFKYFIKFPLTTIKFFLI---FSFKSVEKKISFINSQLSTFRYILRFGYLP 192

Query: 172 INLYKIIKRFRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFG 231
             L   + + + + +                     D +  +Y++ DEL   +KL     
Sbjct: 193 FYLLPYLDKLKSIAKSPH-----TIGKIALNETFLQDTLNIYYSIFDELDTLYKLNLWSN 247

Query: 232 KKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAI 290
                    ++    V       W++  +LA+  N    + L R E+ L +       A+
Sbjct: 248 ---------DQFYNIVGRHEAYSWQLDILLALKNNWLSLKSLERKELELQLKLQFKEEAL 298

Query: 291 KEYELKY-----------------------KLPTNDKV-------------------NLE 308
           +                             K    D V                   +++
Sbjct: 299 ELSNFYNNFNNDNDKNNNNNIINNNDNDDTKTEKPDSVISYSFSNSFSTSDIEQQLKSIK 358

Query: 309 LRKNNITLDFYKIILNLLSN---LINIKGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
            +K  + LD  ++  +L++N   + N+K           Y I+S+ SG+T  +K+W   +
Sbjct: 359 DQKLIVNLDLVRLSFDLMANTTDVFNMKVPTG------TYSILSLCSGITGFIKIWINTR 412
>ref|XP_719137.1| peroxisome regulatory protein Pex25 [Candida albicans SC5314]
 gb|EAL00242.1| potential peroxisome regulatory protein Pex25 [Candida albicans
           SC5314]
          Length = 539

 Score = 82.3 bits (202), Expect = 6e-14,   Method: Composition-based stats.
 Identities = 55/268 (20%), Positives = 95/268 (35%), Gaps = 47/268 (17%)

Query: 128 HTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLREM 187
           H    + ++++   + L  F  K   +I  LS++R +LRFG     +  +I +F      
Sbjct: 275 HPADFIKIIVI---LILSIFKQKAAGMINGLSMYRQFLRFGKTPFRIRDLIVKFHHNVFN 331

Query: 188 KKLHYKDQSILF-YFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTF 246
                + Q      F        +  +Y + DE IL +KL  +                F
Sbjct: 332 NSSDNQVQINKSKIFDRKTLGQFLSLYYGINDESILLYKLNVLSN---------PDYKKF 382

Query: 247 VKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE----------- 294
           V +   I W     LA+    E  + L++ E+ L I       A +  +           
Sbjct: 383 VSKHESIAWHCETWLALYNAYENLQNLLQQEMDLKIQIQVKNKAKQLSKQILLGGNAKGN 442

Query: 295 -----LKYKLPTNDKVNLEL---------RKNNITLDFYKIILNLLSN---LINIKGKRD 337
                L + + T   VN E          +KNN  +D YK + +L  N   + NI    D
Sbjct: 443 DSGGLLGFNISTIPTVNSEDAKNLTQIQFKKNNAWIDIYKNLSDLAFNTYTVFNIALPFD 502

Query: 338 KYNSELAYEIISVGSGVTELLKLWNRAK 365
            +        + + + V   +KL+   K
Sbjct: 503 TWQIW-----MGISASVLSTIKLYRETK 525
>ref|XP_719254.1| peroxisome regulatory protein Pex25 [Candida albicans SC5314]
 gb|EAL00364.1| potential peroxisome regulatory protein Pex25 [Candida albicans
           SC5314]
          Length = 539

 Score = 82.0 bits (201), Expect = 7e-14,   Method: Composition-based stats.
 Identities = 55/268 (20%), Positives = 95/268 (35%), Gaps = 47/268 (17%)

Query: 128 HTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLREM 187
           H    + ++++   + L  F  K   +I  LS++R +LRFG     +  +I +F      
Sbjct: 275 HPADFIKIIVI---LILSIFKQKAAGMINGLSMYRQFLRFGKTPFRIRDLIVKFHHNVFN 331

Query: 188 KKLHYKDQSILF-YFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTF 246
                + Q      F        +  +Y + DE IL +KL  +                F
Sbjct: 332 NSSDNQVQINKSKIFDRKTLGQFLSLYYGINDESILLYKLNVLSN---------PDYKKF 382

Query: 247 VKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE----------- 294
           V +   I W     LA+    E  + L++ E+ L I       A +  +           
Sbjct: 383 VSKHESIAWHCETWLALYNAYENLQNLLQQEMDLKIQIQVKNKAKQLSKQILLGGNAKGN 442

Query: 295 -----LKYKLPTNDKVNLEL---------RKNNITLDFYKIILNLLSN---LINIKGKRD 337
                L + + T   VN E          +KNN  +D YK + +L  N   + NI    D
Sbjct: 443 DSGGLLGFNISTIPTVNSEDAKNLTQIQFKKNNAWIDIYKNLSDLAFNTYTVFNIALPFD 502

Query: 338 KYNSELAYEIISVGSGVTELLKLWNRAK 365
            +        + + + V   +KL+   K
Sbjct: 503 TWQIW-----MGISASVLSTIKLYRETK 525
>ref|XP_001383435.2| hypothetical protein PICST_56779 [Pichia stipitis CBS 6054]
 gb|ABN65406.2| predicted protein [Pichia stipitis CBS 6054]
          Length = 401

 Score = 78.9 bits (193), Expect = 6e-13,   Method: Composition-based stats.
 Identities = 49/264 (18%), Positives = 101/264 (38%), Gaps = 47/264 (17%)

Query: 123 SKILQHT---LGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIK 179
           S  L+H    + ++ +L+ +       F  +   ++  LS++R +LRFG     +  +  
Sbjct: 157 SNFLKHPSDFIRIIVILVCSL------FRERFAGMVSGLSMYRQFLRFGKTPFRIRGLAN 210

Query: 180 RFRWLREMKKLHYKDQSILFYFKNF----RFFDIIEAFYNLTDELILFHKLQSMFGKKNT 235
           +         + YK+  +   + N        ++   +Y + DE +L +KL+ +  +   
Sbjct: 211 KL-----SSNITYKNNDVKINYPNIMNRKTLGEVFSLYYGINDESLLLYKLKFLSNES-- 263

Query: 236 SHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE 294
                     FV       W     LA+    E  + L + E+ + I       A    +
Sbjct: 264 -------YHKFVSRHESFGWYSETWLALYNAYENLQNLTQQEMDVKISIQVKSKAKLLSK 316

Query: 295 -------LKYKLPTNDKV--NLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAY 345
                  +      + KV  +++ +KNN  LD YK I +L+ N   +      +   L +
Sbjct: 317 QLLGSGAVSSSSNEDAKVLSDIQFKKNNAWLDIYKNISDLIFNTYTV------FRLPLPF 370

Query: 346 EIISVGSGVT----ELLKLWNRAK 365
           + I +  G++      +KL+   K
Sbjct: 371 DTIQIWMGISASVLSTVKLYRETK 394
>ref|XP_457136.1| hypothetical protein DEHA0B03894g [Debaryomyces hansenii CBS767]
 emb|CAG85129.1| unnamed protein product [Debaryomyces hansenii CBS767]
          Length = 497

 Score = 71.6 bits (174), Expect = 1e-10,   Method: Composition-based stats.
 Identities = 51/262 (19%), Positives = 93/262 (35%), Gaps = 40/262 (15%)

Query: 126 LQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRF--RW 183
           L H    + +++L   +    F S+L      LSLFR +LRFG       +   +   R 
Sbjct: 244 LHHPRDFIKIIVL---LACSIFRSRLSGTAGGLSLFRQFLRFGQSPFKTRRFKNKLVSRT 300

Query: 184 LREMKKLHYKDQSILF--YFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTN 241
               K   Y          F      DI   +Y++ DE  L +K+     K         
Sbjct: 301 TIATKSGDYMIDVSSIGKCFTKDVLGDIFSLYYSVFDEAGLLYKMNFFRSKS-------- 352

Query: 242 RLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE------ 294
                +     + W    +L I     + ++L + E+ L I       A    +      
Sbjct: 353 -FHKVILRHESLAWYYETLLGIYNAYGRLQKLSQQEMDLKIQIQVKSKARLLSKQLLGAS 411

Query: 295 ----LKYKLPTNDKVNLE---LRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEI 347
               L ++  T D   L+    +K N  +D YK + + + N   +      +N  L ++ 
Sbjct: 412 SIEGLSHEDDTKDAQQLKEIQFKKYNSYIDIYKWLSDFIFNTYTV------FNMALPFDT 465

Query: 348 ISVGSGVT----ELLKLWNRAK 365
           + +  G++     +LKL+   +
Sbjct: 466 LQLWMGISASSLSILKLYRETR 487
>gb|ABG36525.1| Pex25p [Pichia angusta]
          Length = 425

 Score = 68.1 bits (165), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 51/260 (19%), Positives = 93/260 (35%), Gaps = 35/260 (13%)

Query: 138 LTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFR----WLREMKKLHYK 193
           L   + L  F ++   + + LS++R  LR G     + K++ R       L+  +K   K
Sbjct: 169 LIVVLFLGQFEARFVGLTKMLSVYRQMLRAGTVPTKVLKMLSRISESVGLLQSSEKASTK 228

Query: 194 DQSILF-YFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHY 252
            Q +   +       +I   +Y   DE +L +K+  +  K       T     F      
Sbjct: 229 LQRLKSDWCNFKSLGEICALYYAWFDESLLAYKIGLLDEKT------TPNYRKFAVRHEA 282

Query: 253 ILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIK--------EYELKYKLP--- 300
           + W    IL +    E+  QL   E  L I Y     A +        +  +    P   
Sbjct: 283 LAWYTNIILGLRAQFEKLSQLSNKENSLKINYQVKQRAKRLVSTIKPDQSPISLYGPLEV 342

Query: 301 TNDKVNLEL---------RKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVG 351
           T+ K  L+           K  + L+  K++ +   + +N+   +      L +    +G
Sbjct: 343 TDTKTQLQYSTELKKISKEKYMVQLEILKLLCDFAYDTVNVFHLKIDEPLHLLF---GLG 399

Query: 352 SGVTELLKLWNRAKVTSANE 371
           +G   L K+W   K  +  E
Sbjct: 400 AGAISLSKIWIAEKEKTEKE 419
>ref|XP_001523976.1| conserved hypothetical protein [Lodderomyces elongisporus NRRL
           YB-4239]
 gb|EDK46608.1| conserved hypothetical protein [Lodderomyces elongisporus NRRL
           YB-4239]
          Length = 571

 Score = 65.8 bits (159), Expect = 5e-09,   Method: Composition-based stats.
 Identities = 29/157 (18%), Positives = 61/157 (38%), Gaps = 18/157 (11%)

Query: 126 LQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLR 185
           L+H      ++++        F  ++  +I  LS++R +LRFG     ++ ++K+ +   
Sbjct: 305 LKHPQDFFRIIVILVCSI---FKLRVAGMINGLSMYRQFLRFGKTPFRIHDLVKKVQENV 361

Query: 186 EMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMT 245
             K ++ +       F       +   +Y + DE IL +KL  +               +
Sbjct: 362 HSKTINKQ------LFSRSTLSQVASLYYGINDESILLYKLNVLTN---------PWYKS 406

Query: 246 FVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI 282
            V       W +   +A+    E+  +L  + I L I
Sbjct: 407 IVSRHESYAWYLETWIALYNAYEKLGKLSEERINLQI 443
>ref|XP_001485441.1| hypothetical protein PGUG_03169 [Pichia guilliermondii ATCC 6260]
 gb|EDK39072.1| hypothetical protein PGUG_03169 [Pichia guilliermondii ATCC 6260]
          Length = 178

 Score = 58.8 bits (141), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 29/152 (19%), Positives = 56/152 (36%), Gaps = 26/152 (17%)

Query: 205 RFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAIN 264
              D+   +Y + DE++L  KL+    K             +        W    +LA+ 
Sbjct: 5   TLGDLFSLYYGIHDEILLLFKLKFFTSKS---------FQQYAARHESRAWYYETLLALY 55

Query: 265 KNIEQWRQLIRDEIYLSIY------------NTSGNAIKEYELKYKLPTNDKV--NLELR 310
              E+ +QL + E+ + I                G +       Y+ PT+     +++ +
Sbjct: 56  NTYERLQQLSQQEMDMRIQIQVKQRAKLLSKQLLGGSQLLNSSHYEDPTDLNQLKDIQFK 115

Query: 311 KNNITLDFYKIILNLLSN---LINIKGKRDKY 339
           K N  +D YK + +   N   + N+K   D +
Sbjct: 116 KYNAYIDIYKWLADFAFNTYTVFNLKLPFDTF 147
>ref|NP_345727.1| DNA topoisomerase I [Streptococcus pneumoniae TIGR4]
 gb|AAK75367.1| DNA topoisomerase I [Streptococcus pneumoniae TIGR4]
          Length = 699

 Score = 39.6 bits (91), Expect = 0.43,   Method: Composition-based stats.
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS N +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|NP_358734.1| DNA topoisomerase I [Streptococcus pneumoniae R6]
 gb|AAK99944.1| DNA topoisomerase I [Streptococcus pneumoniae R6]
          Length = 701

 Score = 39.6 bits (91), Expect = 0.45,   Method: Composition-based stats.
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS N +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 236 TSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 295

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 296 QQLYEGINIGSGVQGLI 312
>ref|ZP_01407769.1| hypothetical protein SpneT_02001810 [Streptococcus pneumoniae
           TIGR4]
          Length = 693

 Score = 39.6 bits (91), Expect = 0.45,   Method: Composition-based stats.
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS N +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|YP_816589.1| DNA topoisomerase I [Streptococcus pneumoniae D39]
 gb|ABJ54911.1| DNA topoisomerase I [Streptococcus pneumoniae D39]
          Length = 695

 Score = 39.6 bits (91), Expect = 0.45,   Method: Composition-based stats.
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS N +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|ZP_01824014.1| DNA topoisomerase I [Streptococcus pneumoniae SP9-BS68]
 ref|ZP_02713286.1| DNA topoisomerase I [Streptococcus pneumoniae SP195]
 gb|EDK77899.1| DNA topoisomerase I [Streptococcus pneumoniae SP9-BS68]
 gb|EDT93088.1| DNA topoisomerase I [Streptococcus pneumoniae SP195]
          Length = 695

 Score = 39.6 bits (91), Expect = 0.46,   Method: Composition-based stats.
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS N +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|ZP_02717324.1| DNA topoisomerase I [Streptococcus pneumoniae CDC3059-06]
 gb|EDT97271.1| DNA topoisomerase I [Streptococcus pneumoniae CDC3059-06]
          Length = 695

 Score = 39.6 bits (91), Expect = 0.47,   Method: Composition-based stats.
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS N +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|ZP_01818400.1| DNA topoisomerase I [Streptococcus pneumoniae SP3-BS71]
 gb|EDK73724.1| DNA topoisomerase I [Streptococcus pneumoniae SP3-BS71]
          Length = 695

 Score = 38.8 bits (89), Expect = 0.67,   Method: Composition-based stats.
 Identities = 25/96 (26%), Positives = 49/96 (51%), Gaps = 5/96 (5%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS + +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELLKLWNR--AKVTSANEHTSA 375
           +  YE I++GSGV  L+        +++S  ++ +A
Sbjct: 290 QQLYEGINIGSGVQGLITYMRTDSTRISSVAQNEAA 325
>ref|YP_001040065.1| serine proteases-like protein [Staphylothermus marinus F1]
 gb|ABN69157.1| serine proteases-like protein [Staphylothermus marinus F1]
          Length = 655

 Score = 37.7 bits (86), Expect = 1.5,   Method: Composition-based stats.
 Identities = 23/105 (21%), Positives = 47/105 (44%), Gaps = 3/105 (2%)

Query: 174 LYKIIKRFRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKK 233
           +  II +F W   ++ ++  ++S    F     F  I+ +  + +   + ++L+ +  + 
Sbjct: 252 VLNIIDKFAWENYVRSMNLFNESKKL-FNQLDLFTRIQLYDQIKNVEKMNYQLKQLIDE- 309

Query: 234 NTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEI 278
           N S A+       +KE  YI W   +IL    N+E    +I + I
Sbjct: 310 NLSIASFIYSNKVLKENIYINWLYKSILG-KLNLENTISMINETI 353
>ref|ZP_01830742.1| DNA topoisomerase I [Streptococcus pneumoniae SP18-BS74]
 gb|EDK68343.1| DNA topoisomerase I [Streptococcus pneumoniae SP18-BS74]
          Length = 695

 Score = 37.3 bits (85), Expect = 1.9,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS + +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|ZP_01820667.1| DNA topoisomerase I [Streptococcus pneumoniae SP6-BS73]
 ref|ZP_01827565.1| DNA topoisomerase I [Streptococcus pneumoniae SP14-BS69]
 ref|ZP_01833387.1| DNA topoisomerase I [Streptococcus pneumoniae SP19-BS75]
 ref|ZP_02721631.1| DNA topoisomerase I [Streptococcus pneumoniae MLV-016]
 gb|EDK66237.1| DNA topoisomerase I [Streptococcus pneumoniae SP14-BS69]
 gb|EDK70579.1| DNA topoisomerase I [Streptococcus pneumoniae SP19-BS75]
 gb|EDK76344.1| DNA topoisomerase I [Streptococcus pneumoniae SP6-BS73]
 gb|EDT98678.1| DNA topoisomerase I [Streptococcus pneumoniae MLV-016]
          Length = 695

 Score = 37.3 bits (85), Expect = 2.0,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS + +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|YP_001835757.1| DNA topoisomerase I [Streptococcus pneumoniae CGSP14]
 gb|ACB90292.1| DNA topoisomerase I [Streptococcus pneumoniae CGSP14]
          Length = 701

 Score = 37.3 bits (85), Expect = 2.0,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS + +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 236 TSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 295

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 296 QQLYEGINIGSGVQGLI 312
>ref|YP_002738435.1| DNA topoisomerase I [Streptococcus pneumoniae P1031]
 gb|ACO21912.1| DNA topoisomerase I [Streptococcus pneumoniae P1031]
          Length = 695

 Score = 37.3 bits (85), Expect = 2.0,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS + +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|ZP_01834618.1| DNA topoisomerase I [Streptococcus pneumoniae SP23-BS72]
 gb|EDK82105.1| DNA topoisomerase I [Streptococcus pneumoniae SP23-BS72]
          Length = 695

 Score = 37.3 bits (85), Expect = 2.0,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS + +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|ZP_02715323.1| DNA topoisomerase I [Streptococcus pneumoniae CDC0288-04]
 ref|YP_001694689.1| DNA topoisomerase I [Streptococcus pneumoniae Hungary19A-6]
 gb|ACA37265.1| DNA topoisomerase I [Streptococcus pneumoniae Hungary19A-6]
 gb|EDT94934.1| DNA topoisomerase I [Streptococcus pneumoniae CDC0288-04]
          Length = 695

 Score = 37.3 bits (85), Expect = 2.0,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS + +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|YP_002740567.1| DNA topoisomerase I [Streptococcus pneumoniae 70585]
 gb|ACO16687.1| DNA topoisomerase I [Streptococcus pneumoniae 70585]
          Length = 695

 Score = 37.3 bits (85), Expect = 2.0,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS + +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|NP_612284.1| ORF062L [Infectious spleen and kidney necrosis virus]
 gb|AAL98786.1|AF371960_62 ORF062L [infectious spleen and kidney necrosis virus]
          Length = 1208

 Score = 36.5 bits (83), Expect = 3.2,   Method: Composition-based stats.
 Identities = 31/123 (25%), Positives = 46/123 (37%), Gaps = 21/123 (17%)

Query: 189  KLHYK---DQSILFYFKNFRFFDIIEAFYNLTDE-------LIL------FHKLQSMFGK 232
            KL Y+   DQ +  Y + F   D  E F  L  E       L L      F+ L+SM   
Sbjct: 1036 KLGYQVTPDQDMREYLRQFTIRDFGELFKKLDPEGRVFQTPLDLKMYDGYFYTLESMLDY 1095

Query: 233  KNTSHANTNRLMTFVKEQHYILW--EVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAI 290
             +TS         F   Q YI    +    L       Q   +I++EI   + +T   A+
Sbjct: 1096 IDTSTGELRTTQQF---QDYIRLNPQRNTRLRTGPEWTQVVDVIQNEIQQQMLSTQLGAL 1152

Query: 291  KEY 293
             ++
Sbjct: 1153 DQH 1155
>ref|XP_449653.1| hypothetical protein CAGL0M07029g [Candida glabrata CBS138]
 emb|CAG62629.1| unnamed protein product [Candida glabrata CBS 138]
          Length = 838

 Score = 36.5 bits (83), Expect = 3.4,   Method: Composition-based stats.
 Identities = 27/108 (25%), Positives = 48/108 (44%), Gaps = 15/108 (13%)

Query: 231 GKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAI 290
           G    ++  +N+      +Q YI W+ L  LA++      +++I DE+   I+ T   A 
Sbjct: 741 GLSLAANPVSNKFY----DQAYI-WQFLASLALSGK-LNHQRIIIDEVRDEIFGTINTA- 793

Query: 291 KEYELKYKLPTNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDK 338
              E   KLPT D+     R+  +  D     LNL  N++ +  +  +
Sbjct: 794 ---EQLKKLPTEDQNGSLYRREKLYQD-----LNLFLNVMGLVSRDGE 833
>ref|ZP_00366966.1| conserved hypothetical integral membrane protein, putative
           [Campylobacter coli RM2228]
 gb|EAL57612.1| conserved hypothetical integral membrane protein, putative
           [Campylobacter coli RM2228]
          Length = 341

 Score = 36.1 bits (82), Expect = 4.0,   Method: Composition-based stats.
 Identities = 31/129 (24%), Positives = 50/129 (38%), Gaps = 8/129 (6%)

Query: 209 IIEAFYNLTDELILFHKLQSMFG-KKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNI 267
           +I   + L D  + F K Q  F  K           M F+++Q    +E + +    +NI
Sbjct: 121 MIPIVFELQDNFVNFKKTQVKFNYKTGEFGQRFLEWMIFIEKQESDRYENIIMYHPKRNI 180

Query: 268 EQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLPTNDKVNLELRKNNITLDFYKIILNLLS 327
           E   QLI       I   +     E    +KL      N E  +     +F K+I+N   
Sbjct: 181 EDKEQLI-------IAKEATAQRNEDSFAFKLSNGKMYNFENGQTLFIGNFDKLIVNTQF 233

Query: 328 NLINIKGKR 336
           N  N++ K+
Sbjct: 234 NDQNLQTKK 242
>ref|XP_001524758.1| hypothetical protein LELG_03790 [Lodderomyces elongisporus NRRL
           YB-4239]
 gb|EDK45611.1| hypothetical protein LELG_03790 [Lodderomyces elongisporus NRRL
           YB-4239]
          Length = 650

 Score = 36.1 bits (82), Expect = 4.1,   Method: Composition-based stats.
 Identities = 14/85 (16%), Positives = 38/85 (44%), Gaps = 10/85 (11%)

Query: 146 NFSSKLRLVIQQL-SLFRYYLRFGNFAINLYKIIKRFRWLREMKKLHYKDQSILFYFKNF 204
           +F  + R++ +Q+ S+F Y              I  F ++ +  + +Y+++    Y+ N 
Sbjct: 334 HFQKRQRIIQKQMKSIFIY-------PFAYC-FIWLFPFILQTTQFNYEEEHKPVYWLNV 385

Query: 205 RFFDIIEAFYNLTDELILFHKLQSM 229
                ++ F+   D ++ F++ +  
Sbjct: 386 -LGAFMQPFFGFVDSMVFFYRERPW 409
>gb|AAT71873.1| putative DNA-binding protein [Rock bream iridovirus]
          Length = 1253

 Score = 36.1 bits (82), Expect = 4.2,   Method: Composition-based stats.
 Identities = 31/123 (25%), Positives = 45/123 (36%), Gaps = 21/123 (17%)

Query: 189  KLHYK---DQSILFYFKNFRFFDIIEAFYNLTDE-------LIL------FHKLQSMFGK 232
            KL Y+   DQ +  Y + F   D  E F  L  E       L L      F+ L+SM   
Sbjct: 1081 KLGYQVTPDQDMREYLRQFTIRDFGELFKKLDPEGQVFQTPLDLKMYDGYFYTLESMLDY 1140

Query: 233  KNTSHANTNRLMTFVKEQHYILW--EVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAI 290
             + S         F   Q YI    +    L       Q   +I++EI   I +T   A+
Sbjct: 1141 IDPSTGELRTTQQF---QDYIRLNPQRNTRLRTGPEWTQVVDVIQNEIQQQILHTQLGAL 1197

Query: 291  KEY 293
             ++
Sbjct: 1198 DQH 1200
>gb|AAX82370.1| ORF61L [Orange-spotted grouper iridovirus]
          Length = 372

 Score = 36.1 bits (82), Expect = 4.6,   Method: Composition-based stats.
 Identities = 31/123 (25%), Positives = 45/123 (36%), Gaps = 21/123 (17%)

Query: 189 KLHYK---DQSILFYFKNFRFFDIIEAFYNLTDE-------LIL------FHKLQSMFGK 232
           KL Y+   DQ +  Y + F   D  E F  L  E       L L      F+ L+SM   
Sbjct: 200 KLGYQVTPDQDMREYLRQFTIRDFGELFKKLDPEGQVFQTPLDLKMYDGYFYTLESMLDY 259

Query: 233 KNTSHANTNRLMTFVKEQHYILW--EVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAI 290
            + S         F   Q YI    +    L       Q   +I++EI   I +T   A+
Sbjct: 260 IDPSTGELRTTQQF---QDYIRLNPQRNTRLRTGPEWTQVVDVIQNEIQQQILHTQLGAL 316

Query: 291 KEY 293
            ++
Sbjct: 317 DQH 319
>ref|ZP_01826136.1| DNA topoisomerase I [Streptococcus pneumoniae SP11-BS70]
 gb|EDK62582.1| DNA topoisomerase I [Streptococcus pneumoniae SP11-BS70]
          Length = 415

 Score = 36.1 bits (82), Expect = 5.2,   Method: Composition-based stats.
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 3/77 (3%)

Query: 285 TSGNAIKE--YELKYKLPTNDKVNLELRKNNITLDFYKIILNL-LSNLINIKGKRDKYNS 341
           TS + +KE    L  K  + D+V+ + RK N  L +    + +  +N IN + ++    +
Sbjct: 230 TSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAANKINFRTRKTMMVA 289

Query: 342 ELAYEIISVGSGVTELL 358
           +  YE I++GSGV  L+
Sbjct: 290 QQLYEGINIGSGVQGLI 306
>ref|NP_845093.1| hypothetical protein BA2743 [Bacillus anthracis str. Ames]
 ref|YP_019383.1| hypothetical protein GBAA2743 [Bacillus anthracis str. 'Ames
           Ancestor']
 ref|YP_028816.1| hypothetical protein BAS2557 [Bacillus anthracis str. Sterne]
 ref|ZP_02390108.1| conserved hypothetical protein [Bacillus anthracis str. A0442]
 ref|ZP_02606942.1| hypothetical protein BantT_04805 [Bacillus anthracis
           Tsiankovskii-I]
 ref|ZP_02932443.1| conserved hypothetical protein [Bacillus anthracis str. A0174]
 sp|Q81PQ8|Y2743_BACAN UPF0421 protein BA_2743/GBAA2743/BAS2557
 gb|AAP26579.1| conserved hypothetical protein [Bacillus anthracis str. Ames]
 gb|AAT31858.1| conserved hypothetical protein [Bacillus anthracis str. 'Ames
           Ancestor']
 gb|AAT54867.1| conserved hypothetical protein [Bacillus anthracis str. Sterne]
 gb|EDR94715.1| conserved hypothetical protein [Bacillus anthracis str. A0442]
 gb|EDT69573.1| conserved hypothetical protein [Bacillus anthracis str. A0174]
          Length = 355

 Score = 35.3 bits (80), Expect = 8.5,   Method: Composition-based stats.
 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 7/66 (10%)

Query: 208 DIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNI 267
           +I E  + L DEL      Q    K + +H   N+       +  IL+EV   L+I+  +
Sbjct: 282 EIDEEHFKLIDELDK----QFWTNKNDLAHCKPNQYHHHFSSKSIILFEV---LSIHDML 334

Query: 268 EQWRQL 273
           E+ +Q+
Sbjct: 335 EELKQI 340
>ref|ZP_02213167.1| conserved hypothetical protein [Bacillus anthracis str. A0488]
 ref|ZP_02396040.1| conserved hypothetical protein [Bacillus anthracis str. A0193]
 ref|ZP_02894914.1| conserved hypothetical protein [Bacillus anthracis str. A0389]
 gb|EDR20750.1| conserved hypothetical protein [Bacillus anthracis str. A0488]
 gb|EDR89677.1| conserved hypothetical protein [Bacillus anthracis str. A0193]
 gb|EDS99110.1| conserved hypothetical protein [Bacillus anthracis str. A0389]
          Length = 360

 Score = 35.0 bits (79), Expect = 9.0,   Method: Composition-based stats.
 Identities = 18/66 (27%), Positives = 31/66 (46%), Gaps = 7/66 (10%)

Query: 208 DIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNI 267
           +I E  + L DEL      Q    K + +H   N+       +  IL+EV   L+I+  +
Sbjct: 287 EIDEEHFKLIDELDK----QFWTNKNDLAHCKPNQYHHHFSSKSIILFEV---LSIHDML 339

Query: 268 EQWRQL 273
           E+ +Q+
Sbjct: 340 EELKQI 345
>ref|YP_001802698.1| UPF0004-containing protein [Cyanothece sp. ATCC 51142]
 gb|ACB50632.1| UPF0004-containing protein [Cyanothece sp. ATCC 51142]
          Length = 518

 Score = 35.0 bits (79), Expect = 9.6,   Method: Composition-based stats.
 Identities = 16/66 (24%), Positives = 32/66 (48%), Gaps = 4/66 (6%)

Query: 232 KKNTSHANTNRLMTFVKEQHYILWE-VLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAI 290
           K+ T     +   + +  Q+  +WE  L + A N++  ++RQ++RDEI   +     N +
Sbjct: 454 KRKTRWKFWHHFFSIL-RQNTPVWEHYLTVCAHNEHFLEYRQIVRDEIEQQLQEF--NRL 510

Query: 291 KEYELK 296
               +K
Sbjct: 511 SRKPIK 516
Searching..................................................done Results from round 3


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

gb|EDN63529.1|  peroxisome-related protein [Saccharomyces ce...   554   e-156
ref|NP_014836.1|  Peripheral peroxisomal membrane protein in...   551   e-155
ref|NP_986892.1|  AGR226Wp [Ashbya gossypii ATCC 10895] >gi|...   295   4e-78
gb|EDN61031.1|  peroxin [Saccharomyces cerevisiae YJM789]         266   2e-69
ref|NP_015213.1|  Peripheral peroxisomal membrane peroxin re...   265   3e-69
gb|AAT92840.1|  YPL112C [Saccharomyces cerevisiae]                265   4e-69
ref|XP_447712.1|  hypothetical protein CAGL0I10879g [Candida...   259   3e-67
ref|XP_001383435.2|  hypothetical protein PICST_56779 [Pichi...   255   3e-66
ref|XP_719137.1|  peroxisome regulatory protein Pex25 [Candi...   253   1e-65
ref|XP_719254.1|  peroxisome regulatory protein Pex25 [Candi...   253   2e-65
ref|XP_457136.1|  hypothetical protein DEHA0B03894g [Debaryo...   251   7e-65
ref|XP_455112.1|  unnamed protein product [Kluyveromyces lac...   247   9e-64
gb|ABG36525.1|  Pex25p [Pichia angusta]                           247   1e-63
ref|XP_001646454.1|  hypothetical protein Kpol_1048p26 [Vand...   227   1e-57
ref|XP_001523976.1|  conserved hypothetical protein [Loddero...   209   3e-52
ref|XP_001485441.1|  hypothetical protein PGUG_03169 [Pichia...   169   4e-40
Sequences not found previously or not previously below threshold:

ref|XP_001485442.1|  hypothetical protein PGUG_03171 [Pichia...    56   3e-06
ref|XP_001011230.1|  hypothetical protein TTHERM_00145910 [T...    49   7e-04
ref|XP_001485931.1|  hypothetical protein PGUG_01602 [Pichia...    46   0.005
ref|XP_503276.1|  hypothetical protein [Yarrowia lipolytica]...    44   0.018
ref|XP_460264.1|  hypothetical protein DEHA0E23463g [Debaryo...    43   0.048
ref|XP_001014394.2|  hypothetical protein TTHERM_00522160 [T...    38   0.88 
ref|ZP_04019073.1|  exonuclease SbcC family protein [Finegol...    38   0.95 
ref|XP_454263.1|  unnamed protein product [Kluyveromyces lac...    38   1.4  
gb|EEK07414.1|  hypothetical protein BmurDRAFT_15280 [Brachy...    38   1.5  
dbj|BAD95474.1|  Cryhime1 [Paenibacillus popilliae]                37   2.2  
ref|XP_001019375.1|  hypothetical protein TTHERM_00389700 [T...    37   2.6  
ref|XP_001010669.1|  hypothetical protein TTHERM_00112740 [T...    37   2.6  
ref|XP_001709765.1|  Coiled-coil protein [Giardia lamblia AT...    36   4.0  
ref|YP_001488988.1|  two-component response regulator [Arcob...    36   4.2  
ref|NP_348932.1|  Polysaccharide deacetylase-like protein; X...    36   5.3  
dbj|BAD15303.1|  parasporal crystal protein [Paenibacillus l...    36   5.5  
ref|XP_001425614.1|  hypothetical protein GSPATT00029252001 ...    36   5.5  
ref|NP_722265.1|  putative periplasmic sugar-binding protein...    36   6.9  
ref|XP_001351113.1|  IBR domain protein, putative [Plasmodiu...    35   8.1  
sp|Q736X4|Y2776_BACC1  UPF0421 protein BCE_2776                    35   8.3  
ref|YP_001394859.1|  KdpD [Clostridium kluyveri DSM 555] >gi...    35   9.0  
ref|ZP_02600723.1|  hypothetical protein Bcer0_05480 [Bacill...    35   9.3  
ref|YP_500154.1|  hypothetical protein SAOUHSC_01641 [Staphy...    35   9.5  
ref|YP_895262.1|  hypothetical protein BALH_2468 [Bacillus t...    35   9.8  
>gb|EDN63529.1| peroxisome-related protein [Saccharomyces cerevisiae YJM789]
          Length = 376

 Score =  554 bits (1427), Expect = e-156,   Method: Composition-based stats.
 Identities = 371/376 (98%), Positives = 374/376 (99%)

Query: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI 60
           MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKG IAKKPI
Sbjct: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGEIAKKPI 60

Query: 61  VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120
           VLQDNDDSDFTQNQGKVATATSTT+DRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE
Sbjct: 61  VLQDNDDSDFTQNQGKVATATSTTNDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120

Query: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180
           VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR
Sbjct: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180

Query: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240
           FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT
Sbjct: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240

Query: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP 300
           NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKE+ELKYKLP
Sbjct: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEHELKYKLP 300

Query: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL 360
           TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYN ELAYEIISVGSGVTELLKL
Sbjct: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNLELAYEIISVGSGVTELLKL 360

Query: 361 WNRAKVTSANEHTSAV 376
           WN+AKVTSANEHTSAV
Sbjct: 361 WNQAKVTSANEHTSAV 376
>ref|NP_014836.1| Peripheral peroxisomal membrane protein involved in controlling
           peroxisome size and number, interacts with homologous
           protein Pex25p; Pex27p [Saccharomyces cerevisiae]
 sp|Q08580|PEX27_YEAST Peroxisomal membrane protein PEX27 (Peroxin-27)
 emb|CAA99406.1| unnamed protein product [Saccharomyces cerevisiae]
 gb|AAU09786.1| YOR193W [Saccharomyces cerevisiae]
          Length = 376

 Score =  551 bits (1419), Expect = e-155,   Method: Composition-based stats.
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI 60
           MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI
Sbjct: 1   MTSDPVNTNISSPTLTDRNADESWELLKREFNTLFSNLKTDSKEEGNFTDNKGVIAKKPI 60

Query: 61  VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120
           VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE
Sbjct: 61  VLQDNDDSDFTQNQGKVATATSTTSDRSFKRTLGSIEMKKRYVKKNCQAKFVFNTLEGKE 120

Query: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180
           VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR
Sbjct: 121 VCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKR 180

Query: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240
           FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT
Sbjct: 181 FRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240

Query: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP 300
           NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP
Sbjct: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP 300

Query: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL 360
           TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL
Sbjct: 301 TNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKL 360

Query: 361 WNRAKVTSANEHTSAV 376
           WNRAKVTSANEHTSAV
Sbjct: 361 WNRAKVTSANEHTSAV 376
>ref|NP_986892.1| AGR226Wp [Ashbya gossypii ATCC 10895]
 gb|AAS54716.1| AGR226Wp [Ashbya gossypii ATCC 10895]
          Length = 323

 Score =  295 bits (756), Expect = 4e-78,   Method: Composition-based stats.
 Identities = 59/303 (19%), Positives = 118/303 (38%), Gaps = 52/303 (17%)

Query: 97  EMKKRYVKKNCQAKFVFNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQ 156
           + + R V+ +  A   +  L G      +++H + LL L L++       F +K + V  
Sbjct: 34  QYRTRLVQSDPTALARYARLAGAWSWGLLVRHPVTLLKLWLVSVA---KQFEAKSQTVCT 90

Query: 157 QLSLFRYYLRFGNFAINLYKIIKRFRWL-REMKKLHYKDQSILF------YFKNFRFFDI 209
            +S+FR  +RFG+       + ++     R+ +KL   D + +       +       D+
Sbjct: 91  NISIFRQMMRFGSTPFLARALYQKAAATYRQAQKLPAGDTAGVLQVVRGQWLNEPTLTDV 150

Query: 210 IEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQ 269
           +  +Y + DEL L +       K          L  FV     + W+   +L++ K   +
Sbjct: 151 LYLYYGIMDELSLTYSFGLWAHK---------GLYAFVARHEVLSWQYDILLSLKKGWCR 201

Query: 270 WRQLIRDEIYLSI-YNTSGNA----IKE------YELKYKLPTNDKVN------------ 306
            R++    + L I       A     K         +K +L  + ++             
Sbjct: 202 LREINAKILDLEIQCKVRQRAWDISQKLHSARGTSPVKRQLLRDLQLGPTSDMSLTADLD 261

Query: 307 -LELRKNNITLDFYKIILNLLSN---LINIKGKRDKYNSELAYEIISVGSGVTELLKLWN 362
            L   ++ + +DF ++  +LL+N   +  ++           Y  +S+GSG+    KLW 
Sbjct: 262 ALRQERSVLYVDFVRLTFDLLANSTDVFALRTPPG------TYAWLSLGSGMAGFYKLWT 315

Query: 363 RAK 365
           +AK
Sbjct: 316 QAK 318
>gb|EDN61031.1| peroxin [Saccharomyces cerevisiae YJM789]
          Length = 394

 Score =  266 bits (680), Expect = 2e-69,   Method: Composition-based stats.
 Identities = 62/300 (20%), Positives = 122/300 (40%), Gaps = 54/300 (18%)

Query: 99  KKRYVKKNCQAKFVFNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQL 158
           K+     +      +  +         L+H + ++ +LLL+    L NF  K+  + QQL
Sbjct: 108 KRNLTVLDPSVLTYYTKILKNLTVKVALRHPITVIKVLLLSL---LRNFDKKIDFISQQL 164

Query: 159 SLFRYYLRFGNFAINLYKIIKRFRWLREMKKLHYK-DQSILFYFKNFRFFDIIEAFYNLT 217
           S FRY LRFG     +   + +F    + +K +++ DQ    +F      + ++ +Y + 
Sbjct: 165 STFRYILRFGGTPFRVCSFLGKF---NKTRKCNFQIDQIKKIWFDEASLREFLDLYYGIF 221

Query: 218 DELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDE 277
           DEL L +KL+    K            +FV  Q  + W+   +L++  +    + L + +
Sbjct: 222 DELDLLYKLKIWTNKS---------FYSFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQ 272

Query: 278 IYLSI-YNTSGNAIKEYE-LKYKLPTNDKVN---------------------------LE 308
           + L +      NA+     L ++   +D                              ++
Sbjct: 273 LELEVQLKVQNNALLLSPILMHQAHKDDGSQSPIRKQLLNDLNVNNNAEVLIHKQLKAIK 332

Query: 309 LRKNNITLDFYKIILNLLSNL---INIKGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
             K  + LD  ++  + ++N    +N+K  +        Y ++S+GSG+T L+KLW   K
Sbjct: 333 DEKTLVYLDIARLSFDCMANTSDILNLKTPKG------TYAVLSLGSGLTGLVKLWITTK 386
>ref|NP_015213.1| Peripheral peroxisomal membrane peroxin required for the regulation
           of peroxisome size and maintenance, recruits GTPase
           Rho1p to peroxisomes, induced by oleate, interacts with
           homologous protein Pex27p; Pex25p [Saccharomyces
           cerevisiae]
 sp|Q02969|PEX25_YEAST Peroxisomal membrane protein PEX25 (Peroxin-25)
 gb|AAB68249.1| Ypl112cp [Saccharomyces cerevisiae]
          Length = 394

 Score =  265 bits (679), Expect = 3e-69,   Method: Composition-based stats.
 Identities = 62/300 (20%), Positives = 122/300 (40%), Gaps = 54/300 (18%)

Query: 99  KKRYVKKNCQAKFVFNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQL 158
           K+     +      +  +         L+H + ++ +LLL+    L NF  K+  + QQL
Sbjct: 108 KRNLTVLDPSVLTYYTKILKNLTVKVALRHPITVIKVLLLSL---LRNFDKKIDFISQQL 164

Query: 159 SLFRYYLRFGNFAINLYKIIKRFRWLREMKKLHYK-DQSILFYFKNFRFFDIIEAFYNLT 217
           S FRY LRFG     +   + +F    + +K +++ DQ    +F      + ++ +Y + 
Sbjct: 165 STFRYILRFGGTPFRVCSFLGKF---NKTRKCNFQIDQIKKIWFNEASLREFLDLYYGIF 221

Query: 218 DELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDE 277
           DEL L +KL+    K            +FV  Q  + W+   +L++  +    + L + +
Sbjct: 222 DELDLLYKLKIWTNKS---------FYSFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQ 272

Query: 278 IYLSI-YNTSGNAIKEYE-LKYKLPTNDKVN---------------------------LE 308
           + L +      NA+     L ++   +D                              ++
Sbjct: 273 LELEVQLKVQNNALLLSPILMHQAHKDDGSQSPIRKQLLNDLNVNNDAEVLIHKQLKAIK 332

Query: 309 LRKNNITLDFYKIILNLLSNL---INIKGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
             K  + LD  ++  + ++N    +N+K  +        Y ++S+GSG+T L+KLW   K
Sbjct: 333 DEKTLVYLDIARLSFDCMANTSDILNLKTPKG------TYAVLSLGSGLTGLVKLWITTK 386
>gb|AAT92840.1| YPL112C [Saccharomyces cerevisiae]
          Length = 394

 Score =  265 bits (677), Expect = 4e-69,   Method: Composition-based stats.
 Identities = 62/300 (20%), Positives = 122/300 (40%), Gaps = 54/300 (18%)

Query: 99  KKRYVKKNCQAKFVFNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQL 158
           K+     +      +  +         L+H + ++ +LLL+    L NF  K+  + QQL
Sbjct: 108 KRNLTVLDPSVLTYYTKILKNLTVKVALRHPITVIKVLLLSL---LRNFDKKIDFISQQL 164

Query: 159 SLFRYYLRFGNFAINLYKIIKRFRWLREMKKLHYK-DQSILFYFKNFRFFDIIEAFYNLT 217
           S FRY LRFG     +   + +F    + +K +++ DQ    +F      + ++ +Y + 
Sbjct: 165 STFRYILRFGGTPFRVCSFLGKF---NKTRKCNFQIDQIKKIWFNEASLREFLDLYYGIF 221

Query: 218 DELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDE 277
           DEL L +KL+    K            +FV  Q  + W+   +L++  +    + L + +
Sbjct: 222 DELDLLYKLKIWTNKS---------FYSFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQ 272

Query: 278 IYLSI-YNTSGNAIKEYE-LKYKLPTNDKVN---------------------------LE 308
           + L +      NA+     L ++   +D                              ++
Sbjct: 273 LELEVQLKVQNNALLLSPILMHQAHKDDGSQSPIRKQLLNDLNVNNDAEVLIHKQLKAIK 332

Query: 309 LRKNNITLDFYKIILNLLSNL---INIKGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
             K  + LD  ++  + ++N    +N+K  +        Y ++S+GSG+T L+KLW   K
Sbjct: 333 DEKTLVYLDIARLSFDCMANTSDILNLKTPKG------TYAVLSLGSGLTGLVKLWITTK 386
>ref|XP_447712.1| hypothetical protein CAGL0I10879g [Candida glabrata CBS138]
 emb|CAG60657.1| unnamed protein product [Candida glabrata CBS 138]
          Length = 363

 Score =  259 bits (661), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 53/305 (17%), Positives = 119/305 (39%), Gaps = 57/305 (18%)

Query: 99  KKRYVKKNCQAKFVFNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQL 158
           ++  V+ + Q    +  +        +L+H + +  + ++       NF  K   + QQL
Sbjct: 78  RENIVRWDPQVLTYYKKVLKDLKWWMMLRHPITIAKIWVVAMS---RNFEIKASYLSQQL 134

Query: 159 SLFRYYLRFGNFAINLYKIIKRFRWLRE---MKKLHYKDQSILFYFKNFRFFDIIEAFYN 215
           S +RY LRFG+    +  I K+     +                +F      ++I     
Sbjct: 135 STYRYILRFGSSPFQVLNIWKKLAQTYKEGLTASC-----IHKLWFNEDSIREVINLHNT 189

Query: 216 LTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIR 275
           + DEL+L +KL+    K             ++++Q  I WE   + ++   + + +++ +
Sbjct: 190 VCDELVLLYKLKVWDHK---------DFYNWLEKQEAISWEADILFSLKNKLIELQEMKQ 240

Query: 276 DEIYLSI-YNTSGNAIKE-----------YELKYKLP-----------TNDKVNLELRKN 312
               + I       A++              +  +L            T  +++ +L + 
Sbjct: 241 KRYEMLIDLRARRQALELSKSLHRSRENMSPIHNQLLHEFDNSDDWRRTELEISSQLEEY 300

Query: 313 -----NITLDFYKIILNLLSN---LINIKGKRDKYNSELAYEIISVGSGVTELLKLWNRA 364
                 I LD  ++  +L++N   ++N++  R        Y + S+GSG++ L+KLW+  
Sbjct: 301 RHGISMIYLDIMRLSCDLIANTTDVLNMRVPRG------TYAVFSLGSGLSGLMKLWHTT 354

Query: 365 KVTSA 369
           ++   
Sbjct: 355 RMDLE 359
>ref|XP_001383435.2| hypothetical protein PICST_56779 [Pichia stipitis CBS 6054]
 gb|ABN65406.2| predicted protein [Pichia stipitis CBS 6054]
          Length = 401

 Score =  255 bits (653), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 49/276 (17%), Positives = 102/276 (36%), Gaps = 42/276 (15%)

Query: 111 FVFNTLEGKEVC-SKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGN 169
             +N  E +    S  L+H    + ++++        F  +   ++  LS++R +LRFG 
Sbjct: 144 ARYNNKEKQLNLISNFLKHPSDFIRIIVILVCSL---FRERFAGMVSGLSMYRQFLRFGK 200

Query: 170 FAINLYKIIKRFRWLREMKKLHYKDQSILFYF----KNFRFFDIIEAFYNLTDELILFHK 225
               +  +  +         + YK+  +   +          ++   +Y + DE +L +K
Sbjct: 201 TPFRIRGLANKL-----SSNITYKNNDVKINYPNIMNRKTLGEVFSLYYGINDESLLLYK 255

Query: 226 LQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YN 284
           L+ +  +             FV       W     LA+    E  + L + E+ + I   
Sbjct: 256 LKFLSNES---------YHKFVSRHESFGWYSETWLALYNAYENLQNLTQQEMDVKISIQ 306

Query: 285 TSGNAIKEYE-------LKYKLPTNDKV--NLELRKNNITLDFYKIILNLLSNLINIKGK 335
               A    +       +      + KV  +++ +KNN  LD YK I +L+ N   +   
Sbjct: 307 VKSKAKLLSKQLLGSGAVSSSSNEDAKVLSDIQFKKNNAWLDIYKNISDLIFNTYTV--- 363

Query: 336 RDKYNSELAYEIISVGSGVT----ELLKLWNRAKVT 367
              +   L ++ I +  G++      +KL+   K  
Sbjct: 364 ---FRLPLPFDTIQIWMGISASVLSTVKLYRETKKK 396
>ref|XP_719137.1| peroxisome regulatory protein Pex25 [Candida albicans SC5314]
 gb|EAL00242.1| potential peroxisome regulatory protein Pex25 [Candida albicans
           SC5314]
          Length = 539

 Score =  253 bits (647), Expect = 1e-65,   Method: Composition-based stats.
 Identities = 56/283 (19%), Positives = 98/283 (34%), Gaps = 48/283 (16%)

Query: 122 CSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRF 181
                 H    + ++++   + L  F  K   +I  LS++R +LRFG     +  +I +F
Sbjct: 269 LKNFFNHPADFIKIIVI---LILSIFKQKAAGMINGLSMYRQFLRFGKTPFRIRDLIVKF 325

Query: 182 RWLREMKKLHYKDQSILF-YFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240
                      + Q      F        +  +Y + DE IL +KL  +           
Sbjct: 326 HHNVFNNSSDNQVQINKSKIFDRKTLGQFLSLYYGINDESILLYKLNVLSN--------- 376

Query: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE----- 294
                FV +   I W     LA+    E  + L++ E+ L I       A +  +     
Sbjct: 377 PDYKKFVSKHESIAWHCETWLALYNAYENLQNLLQQEMDLKIQIQVKNKAKQLSKQILLG 436

Query: 295 -----------LKYKLPTNDKVN---------LELRKNNITLDFYKIILNLLSN---LIN 331
                      L + + T   VN         ++ +KNN  +D YK + +L  N   + N
Sbjct: 437 GNAKGNDSGGLLGFNISTIPTVNSEDAKNLTQIQFKKNNAWIDIYKNLSDLAFNTYTVFN 496

Query: 332 IKGKRDKYNSELAYEIISVGSGVTELLKLWNRAKVTS-ANEHT 373
           I    D +        + + + V   +KL+   K      E T
Sbjct: 497 IALPFDTWQI-----WMGISASVLSTIKLYRETKQKMIEKELT 534
>ref|XP_719254.1| peroxisome regulatory protein Pex25 [Candida albicans SC5314]
 gb|EAL00364.1| potential peroxisome regulatory protein Pex25 [Candida albicans
           SC5314]
          Length = 539

 Score =  253 bits (646), Expect = 2e-65,   Method: Composition-based stats.
 Identities = 56/283 (19%), Positives = 98/283 (34%), Gaps = 48/283 (16%)

Query: 122 CSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRF 181
                 H    + ++++   + L  F  K   +I  LS++R +LRFG     +  +I +F
Sbjct: 269 LKNFFNHPADFIKIIVI---LILSIFKQKAAGMINGLSMYRQFLRFGKTPFRIRDLIVKF 325

Query: 182 RWLREMKKLHYKDQSILF-YFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANT 240
                      + Q      F        +  +Y + DE IL +KL  +           
Sbjct: 326 HHNVFNNSSDNQVQINKSKIFDRKTLGQFLSLYYGINDESILLYKLNVLSN--------- 376

Query: 241 NRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE----- 294
                FV +   I W     LA+    E  + L++ E+ L I       A +  +     
Sbjct: 377 PDYKKFVSKHESIAWHCETWLALYNAYENLQNLLQQEMDLKIQIQVKNKAKQLSKQILLG 436

Query: 295 -----------LKYKLPTNDKVN---------LELRKNNITLDFYKIILNLLSN---LIN 331
                      L + + T   VN         ++ +KNN  +D YK + +L  N   + N
Sbjct: 437 GNAKGNDSGGLLGFNISTIPTVNSEDAKNLTQIQFKKNNAWIDIYKNLSDLAFNTYTVFN 496

Query: 332 IKGKRDKYNSELAYEIISVGSGVTELLKLWNRAKVTS-ANEHT 373
           I    D +        + + + V   +KL+   K      E T
Sbjct: 497 IALPFDTWQI-----WMGISASVLSTIKLYRETKQKMIEKELT 534
>ref|XP_457136.1| hypothetical protein DEHA0B03894g [Debaryomyces hansenii CBS767]
 emb|CAG85129.1| unnamed protein product [Debaryomyces hansenii CBS767]
          Length = 497

 Score =  251 bits (641), Expect = 7e-65,   Method: Composition-based stats.
 Identities = 51/266 (19%), Positives = 93/266 (34%), Gaps = 40/266 (15%)

Query: 122 CSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRF 181
               L H    + +++L   +    F S+L      LSLFR +LRFG       +   + 
Sbjct: 240 LKNFLHHPRDFIKIIVL---LACSIFRSRLSGTAGGLSLFRQFLRFGQSPFKTRRFKNKL 296

Query: 182 --RWLREMKKLHYKDQSILF--YFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSH 237
             R     K   Y          F      DI   +Y++ DE  L +K+     K     
Sbjct: 297 VSRTTIATKSGDYMIDVSSIGKCFTKDVLGDIFSLYYSVFDEAGLLYKMNFFRSKS---- 352

Query: 238 ANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE-- 294
                    +     + W    +L I     + ++L + E+ L I       A    +  
Sbjct: 353 -----FHKVILRHESLAWYYETLLGIYNAYGRLQKLSQQEMDLKIQIQVKSKARLLSKQL 407

Query: 295 --------LKYKLPTNDKVNL---ELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSEL 343
                   L ++  T D   L   + +K N  +D YK + + + N   +      +N  L
Sbjct: 408 LGASSIEGLSHEDDTKDAQQLKEIQFKKYNSYIDIYKWLSDFIFNTYTV------FNMAL 461

Query: 344 AYEIISVGSGVT----ELLKLWNRAK 365
            ++ + +  G++     +LKL+   +
Sbjct: 462 PFDTLQLWMGISASSLSILKLYRETR 487
>ref|XP_455112.1| unnamed protein product [Kluyveromyces lactis]
 emb|CAG97819.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
          Length = 431

 Score =  247 bits (631), Expect = 9e-64,   Method: Composition-based stats.
 Identities = 64/294 (21%), Positives = 109/294 (37%), Gaps = 57/294 (19%)

Query: 113 FNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAI 172
           +  L  K     IL++   L   L L+   +L  F  K  LV  QL  +R  +R G    
Sbjct: 153 YLKLFSKGNLLTILRNP-RLSGKLFLSSSSKL--FLEKGALVSSQLGFYRQIMRCGGTPF 209

Query: 173 NLY----KIIKRFRWLREMKKLHYKDQS-ILFYFKNFRFFDIIEAFYNLTDELILFHKLQ 227
            LY    K+I  F   ++   LH K       ++      + I+ +Y + DEL+L +KL+
Sbjct: 210 RLYHWYQKLISTFYASQKSSTLHSKGLVWYKNWWNEESLSEFIDLYYGIMDELMLLYKLK 269

Query: 228 SMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTS 286
               K          +  +V +   + W    +L + KN E+ + + + E  L I Y   
Sbjct: 270 LWSNKS---------MHAWVSKHEALSWYYDIMLGLKKNWEKLQSIKQQEFELKIQYQVR 320

Query: 287 GNAIKEYELKYKLP-------------------TNDKVNL-----------ELRKNNITL 316
             A++        P                     D ++L           +  K  +  
Sbjct: 321 QRALELSSKLNATPSVDSNKNTALIKQTIFESFKQDNLDLELEVVQKLKNYQYEKRIVKF 380

Query: 317 DFYKIILNLLS---NLINIKGKRDKYNSELAYEIISVGSGVTELLKLWNRAKVT 367
           D  ++  + L+   ++ +IK           Y I+S+ SGV    KLW +AK  
Sbjct: 381 DLTRLFFDFLADTTDVFSIKTPPG------TYAILSLCSGVLGFSKLWIQAKEQ 428
>gb|ABG36525.1| Pex25p [Pichia angusta]
          Length = 425

 Score =  247 bits (631), Expect = 1e-63,   Method: Composition-based stats.
 Identities = 54/273 (19%), Positives = 97/273 (35%), Gaps = 39/273 (14%)

Query: 129 TLGLLSLLL----LTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRW- 183
           T  +L  L+    L   + L  F ++   + + LS++R  LR G     + K++ R    
Sbjct: 156 TQDVLRQLVARPELIVVLFLGQFEARFVGLTKMLSVYRQMLRAGTVPTKVLKMLSRISES 215

Query: 184 ---LREMKKLHYKDQSILF-YFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHAN 239
              L+  +K   K Q +   +       +I   +Y   DE +L +K+  +  K       
Sbjct: 216 VGLLQSSEKASTKLQRLKSDWCNFKSLGEICALYYAWFDESLLAYKIGLLDEKT------ 269

Query: 240 TNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAIKE------ 292
           T     F      + W    IL +    E+  QL   E  L I Y     A +       
Sbjct: 270 TPNYRKFAVRHEALAWYTNIILGLRAQFEKLSQLSNKENSLKINYQVKQRAKRLVSTIKP 329

Query: 293 --YELKYKLP---TNDKVNLEL---------RKNNITLDFYKIILNLLSNLINIKGKRDK 338
               +    P   T+ K  L+           K  + L+  K++ +   + +N+   +  
Sbjct: 330 DQSPISLYGPLEVTDTKTQLQYSTELKKISKEKYMVQLEILKLLCDFAYDTVNVFHLKID 389

Query: 339 YNSELAYEIISVGSGVTELLKLWNRAKVTSANE 371
               L +    +G+G   L K+W   K  +  E
Sbjct: 390 EPLHLLF---GLGAGAISLSKIWIAEKEKTEKE 419
>ref|XP_001646454.1| hypothetical protein Kpol_1048p26 [Vanderwaltozyma polyspora DSM
           70294]
 gb|EDO18596.1| hypothetical protein Kpol_1048p26 [Vanderwaltozyma polyspora DSM
           70294]
          Length = 418

 Score =  227 bits (579), Expect = 1e-57,   Method: Composition-based stats.
 Identities = 54/300 (18%), Positives = 101/300 (33%), Gaps = 70/300 (23%)

Query: 113 FNTLEGKEVCSK-ILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFA 171
           FN L+G     K  ++  L  +   L+       +   K+  +  QLS FRY LRFG   
Sbjct: 136 FNKLKGNYSLFKYFIKFPLTTIKFFLI---FSFKSVEKKISFINSQLSTFRYILRFGYLP 192

Query: 172 INLYKIIKRFRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFG 231
             L   + + + + +                     D +  +Y++ DEL   +KL     
Sbjct: 193 FYLLPYLDKLKSIAKSPH-----TIGKIALNETFLQDTLNIYYSIFDELDTLYKLNLWSN 247

Query: 232 KKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSI-YNTSGNAI 290
                    ++    V       W++  +LA+  N    + L R E+ L +       A+
Sbjct: 248 ---------DQFYNIVGRHEAYSWQLDILLALKNNWLSLKSLERKELELQLKLQFKEEAL 298

Query: 291 KEYELKY-----------------------KLPTNDKV-------------------NLE 308
           +                             K    D V                   +++
Sbjct: 299 ELSNFYNNFNNDNDKNNNNNIINNNDNDDTKTEKPDSVISYSFSNSFSTSDIEQQLKSIK 358

Query: 309 LRKNNITLDFYKIILNLLSN---LINIKGKRDKYNSELAYEIISVGSGVTELLKLWNRAK 365
            +K  + LD  ++  +L++N   + N+K           Y I+S+ SG+T  +K+W   +
Sbjct: 359 DQKLIVNLDLVRLSFDLMANTTDVFNMKVPTG------TYSILSLCSGITGFIKIWINTR 412
>ref|XP_001523976.1| conserved hypothetical protein [Lodderomyces elongisporus NRRL
           YB-4239]
 gb|EDK46608.1| conserved hypothetical protein [Lodderomyces elongisporus NRRL
           YB-4239]
          Length = 571

 Score =  209 bits (532), Expect = 3e-52,   Method: Composition-based stats.
 Identities = 47/285 (16%), Positives = 96/285 (33%), Gaps = 65/285 (22%)

Query: 124 KILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRW 183
             L+H      ++++        F  ++  +I  LS++R +LRFG     ++ ++K+ + 
Sbjct: 303 NFLKHPQDFFRIIVILV---CSIFKLRVAGMINGLSMYRQFLRFGKTPFRIHDLVKKVQE 359

Query: 184 LREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRL 243
               K ++ +       F       +   +Y + DE IL +KL  +              
Sbjct: 360 NVHSKTINKQL------FSRSTLSQVASLYYGINDESILLYKLNVLTN---------PWY 404

Query: 244 MTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIY-------------------- 283
            + V       W +   +A+    E+  +L  + I L I                     
Sbjct: 405 KSIVSRHESYAWYLETWIALYNAYEKLGKLSEERINLQIQIHVKAKAKAMAKQFSNGNMH 464

Query: 284 NTSGNAIKEYELKY--------KLPTNDKVNLELRKN---------NITLDFYKIILNLL 326
             +G A      K               K+++E +K          N  +D YK + +L 
Sbjct: 465 QGNGGANFLNMFKNTNSGANNGDDELKPKLSIEEQKQLEDLLFKIHNTWIDIYKNLADLG 524

Query: 327 SNLINIKGKRDKYNSELAYEIISVGSGVT----ELLKLWNRAKVT 367
            N   +      +  +L ++   +  G+T      +KL+   K  
Sbjct: 525 FNTYTV------FKLKLPFQTWQIWMGITASVLSSIKLYRETKRK 563
>ref|XP_001485441.1| hypothetical protein PGUG_03169 [Pichia guilliermondii ATCC 6260]
 gb|EDK39072.1| hypothetical protein PGUG_03169 [Pichia guilliermondii ATCC 6260]
          Length = 178

 Score =  169 bits (428), Expect = 4e-40,   Method: Composition-based stats.
 Identities = 32/184 (17%), Positives = 65/184 (35%), Gaps = 33/184 (17%)

Query: 202 KNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNIL 261
                 D+   +Y + DE++L  KL+    K             +        W    +L
Sbjct: 2   TRKTLGDLFSLYYGIHDEILLLFKLKFFTSKS---------FQQYAARHESRAWYYETLL 52

Query: 262 AINKNIEQWRQLIRDEIYLSI-YNTSGNAIKEYE-----------LKYKLPTNDKV--NL 307
           A+    E+ +QL + E+ + I       A    +             Y+ PT+     ++
Sbjct: 53  ALYNTYERLQQLSQQEMDMRIQIQVKQRAKLLSKQLLGGSQLLNSSHYEDPTDLNQLKDI 112

Query: 308 ELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISVGSGVT----ELLKLWNR 363
           + +K N  +D YK + +   N   +      +N +L ++   +  G+T      +KL+  
Sbjct: 113 QFKKYNAYIDIYKWLADFAFNTYTV------FNLKLPFDTFQIWMGITASLLSSIKLYRE 166

Query: 364 AKVT 367
               
Sbjct: 167 TNKK 170
>ref|XP_001485442.1| hypothetical protein PGUG_03171 [Pichia guilliermondii ATCC 6260]
 gb|EDK39073.1| hypothetical protein PGUG_03171 [Pichia guilliermondii ATCC 6260]
          Length = 265

 Score = 56.4 bits (135), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 13/57 (22%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 113 FNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGN 169
           ++      +    L+H    L ++++   +    FSS+L  ++  L+++R +LRFG 
Sbjct: 193 YDRTAKLSLLQNFLKHPANFLRIVII---LFCSIFSSRLTPLVGGLAMYRQFLRFGK 246
>ref|XP_001011230.1| hypothetical protein TTHERM_00145910 [Tetrahymena thermophila
           SB210]
 gb|EAR90985.1| hypothetical protein TTHERM_00145910 [Tetrahymena thermophila
           SB210]
          Length = 252

 Score = 48.7 bits (115), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 33/180 (18%), Positives = 60/180 (33%), Gaps = 25/180 (13%)

Query: 149 SKLRLVIQQLSLFRYYLRFG---NFAINLYKIIKRFRWLREMKKLHYKDQSILFYFKNFR 205
           S++  +   +SL R  LRFG     +  L  +IK+     +  K     +   FY    R
Sbjct: 59  SRIERLSGNMSLTRKVLRFGRPIGLSFTLIDLIKQLNNSLKNPKSVTDIKQSPFYIT-MR 117

Query: 206 FFDIIEA-FYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAIN 264
               I    + L D ++ F +L  M  KK           +         W +  +  + 
Sbjct: 118 IGSTISLILFFLLDHILYFARLDLM--KKRPELTKFADFYS------SFWWFLDCLFGLT 169

Query: 265 KNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLPTNDKVNLELRKNNITLDFYKIILN 324
            NI++ + L      L       NA +    + K          +    +  D ++ I +
Sbjct: 170 SNIQEIKYL----FEL------NNAERLSSNENKGEKIKSNKARIDAAIV--DAFRNIFD 217
>ref|XP_001485931.1| hypothetical protein PGUG_01602 [Pichia guilliermondii ATCC 6260]
 gb|EDK37504.1| hypothetical protein PGUG_01602 [Pichia guilliermondii ATCC 6260]
          Length = 284

 Score = 46.0 bits (108), Expect = 0.005,   Method: Composition-based stats.
 Identities = 40/166 (24%), Positives = 66/166 (39%), Gaps = 25/166 (15%)

Query: 182 RWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTN 241
           R +R    L  K          F F  ++E   NL D L LF KL            +TN
Sbjct: 96  RRIRRQVNLGSKFTLKKL---EFIFVQVLEMVANLLDNLHLFLKLPGFPEGLVKVLLHTN 152

Query: 242 RLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDE----IYLSIYNTSGNAIKEYELKY 297
           +L           W ++ +  I K + Q   +IR E    + L+I + S N+      + 
Sbjct: 153 KL-----------WVLILVFLIRKTVLQLLNVIRKEKKVNVELNILSQSKNSKVLLNSES 201

Query: 298 KLPTN-----DKV--NLELRKNNITLDFYKIILNLLSNLINIKGKR 336
           + P+N     +KV  +L   K+ + L+     ++L  N+I + G  
Sbjct: 202 QDPSNIYRKYEKVLKDLRFDKSMLVLELIGNFMDLAFNVIELYGVP 247
>ref|XP_503276.1| hypothetical protein [Yarrowia lipolytica]
 emb|CAG81480.1| unnamed protein product [Yarrowia lipolytica CLIB122]
          Length = 299

 Score = 44.1 bits (103), Expect = 0.018,   Method: Composition-based stats.
 Identities = 30/229 (13%), Positives = 68/229 (29%), Gaps = 56/229 (24%)

Query: 143 RLLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLREMKKLHYKDQSILFYFK 202
           +L    S+L  ++   S FR  ++ G +   +  ++              K+      F+
Sbjct: 117 KLAEMESRLNGMVSNFSQFRKIIKLGEWLGPVEDLV------------TTKNPLTSLAFQ 164

Query: 203 NFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILA 262
                +++E    + D++    K+  + GK+     N   +  +        W     + 
Sbjct: 165 ----SELMEVINTIGDDIYCLSKIGVVKGKRLGR--NGELMANW-------GWYGAIFIN 211

Query: 263 INKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLPTNDKVNLELRKNNITLDFYKII 322
           I   IE ++   +     +I++                               L  +K+ 
Sbjct: 212 IKVGIETYQLAAKSGDEAAIWDAK-----------------------------LTLFKLA 242

Query: 323 LNLLSNLINIKGKRDKYNSELAYEIISVGSGVTELLKLWNRAKVTSANE 371
            + +   I+        N      +  + SG     KLW +       E
Sbjct: 243 NDFIFCTIDCLEPEGLSNIYQT--VTGLASGSVGFYKLWRKISKKLDKE 289
>ref|XP_460264.1| hypothetical protein DEHA0E23463g [Debaryomyces hansenii CBS767]
 emb|CAG88545.1| unnamed protein product [Debaryomyces hansenii CBS767]
          Length = 284

 Score = 42.6 bits (99), Expect = 0.048,   Method: Composition-based stats.
 Identities = 39/184 (21%), Positives = 64/184 (34%), Gaps = 28/184 (15%)

Query: 184 LREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRL 243
               +KL ++              +I+E   N+ D L LF +      +       TN+L
Sbjct: 97  TNPNRKLPFQYTFKNI---EKVLIEILETLANILDNLHLFSRFPMFPARLVDLLKQTNKL 153

Query: 244 MTFVKEQHYILWEVLNILAINKNIEQWRQLIRDE----IYLSIYNTSGNAIKE------- 292
                      W V+ I  I K+I Q   +IR E    I LSI N + N+          
Sbjct: 154 -----------WVVILIFLIRKSISQLLNVIRKERKVNIELSILNLNKNSKLLINKDDNN 202

Query: 293 --YELKYKLPTNDKVNLELRKNNITLDFYKIILNLLSNLINIKGKRDKYNSELAYEIISV 350
               +  +     K +L+  K  + L+     L++  NLI + G              S+
Sbjct: 203 GDNNIFRRYEKVLK-DLQFDKMMLVLELIGNFLDMGFNLIELYGIPVPEWFMSLLNAASM 261

Query: 351 GSGV 354
           G  +
Sbjct: 262 GMTI 265
>ref|XP_001014394.2| hypothetical protein TTHERM_00522160 [Tetrahymena thermophila
           SB210]
 gb|EAR94149.2| hypothetical protein TTHERM_00522160 [Tetrahymena thermophila
           SB210]
          Length = 232

 Score = 38.3 bits (88), Expect = 0.88,   Method: Composition-based stats.
 Identities = 29/213 (13%), Positives = 75/213 (35%), Gaps = 27/213 (12%)

Query: 114 NTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFAIN 173
           N  EG++   K +Q+    L              +++   +   +   R   R       
Sbjct: 9   NKTEGRDKFCKAIQYASRFLKWHF--TNTENKELAARFNGLFNGMKDARKLFRL----FK 62

Query: 174 LYKIIKRFRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELILFHKLQSMFGKK 233
               I++ + L     L+ KD   +    N         ++   D L++   ++ + G  
Sbjct: 63  TINEIQKIQEL-----LNKKDNDEINKALNILVRAFFGLYW-YFDNLVILKSVKFIHGDP 116

Query: 234 NTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEY 293
              +           ++    W +  +L+I +NI    + +++E  L +     N +++ 
Sbjct: 117 KPDN-----------KKGSTCWLIALLLSIAQNIRNLLKSLQEEANL-VKQVLENQVEQE 164

Query: 294 ELKYKLPTNDKVNLELRKNNITLDFYKIILNLL 326
            +K     +    ++ ++ +I L   K + + +
Sbjct: 165 SVKLN---DQIAKIKKQRFDIYLSIIKNLGDTI 194
>ref|ZP_04019073.1| exonuclease SbcC family protein [Finegoldia magna ATCC 53516]
 gb|EEJ67933.1| exonuclease SbcC family protein [Finegoldia magna ATCC 53516]
          Length = 527

 Score = 38.3 bits (88), Expect = 0.95,   Method: Composition-based stats.
 Identities = 36/158 (22%), Positives = 63/158 (39%), Gaps = 13/158 (8%)

Query: 180 RFRWLRE-MKKLHYKDQSILFYFKNFRFFDIIE-AFYNLTDELILFHKLQSMFGKKNTSH 237
           +   L E  +++    +S      N R+ D+I     N+   L L   L+ ++ +     
Sbjct: 273 KLYQLYEYSQEIIKGIESSNVKLNNLRYTDLISEIIDNIDKNLTLLKFLKPLYDRFTYVK 332

Query: 238 ANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIR-DEIYLSIYN---------TSG 287
           ++ N   T +++   +      +L    +I+   QL    E Y  I           TS 
Sbjct: 333 SSYNNYKTILEKFKQVPKSYNILLNTQNDIQILNQLSNLSENYYRINQEIMDNSQVLTSI 392

Query: 288 NAIKEYELKYKLPTNDKVNLELRKNNI-TLDFYKIILN 324
           N  K  EL  ++  N +  ++L K NI  L   KIIL+
Sbjct: 393 NTSKVSELTNRIDKNKEKYIQLYKLNISYLKINKIILD 430
>ref|XP_454263.1| unnamed protein product [Kluyveromyces lactis]
 sp|Q6CP76|ATM_KLULA Serine/threonine-protein kinase TEL1 (DNA-damage checkpoint kinase
            TEL1) (Telomere length regulation protein 1) (ATM
            homolog)
 emb|CAG99350.1| unnamed protein product [Kluyveromyces lactis NRRL Y-1140]
          Length = 2761

 Score = 38.0 bits (87), Expect = 1.4,   Method: Composition-based stats.
 Identities = 35/148 (23%), Positives = 49/148 (33%), Gaps = 20/148 (13%)

Query: 118  GKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRFGNFA------ 171
            GK+   KIL   +  L   L  R + LL    K   V  Q  LF+  L+  N        
Sbjct: 947  GKQRVFKILSGCITRLPKYLTNRVVSLLGTYVKRVGVTNQRILFKELLQRFNPPQESVET 1006

Query: 172  ---INL----YKIIKRFRWLREMKKL-HYKDQSILFYFKNFRFFDIIEAFYNLTDELILF 223
                +L      +I  F  L  +  L    + S L  +      D I  FY L  +  LF
Sbjct: 1007 AAFFSLTCTKLSLINEFYLLNSILHLLDNTNFSHLLLYVEKSL-DTISTFYGLCSKQDLF 1065

Query: 224  HK-----LQSMFGKKNTSHANTNRLMTF 246
            H+     +   F K   S      +   
Sbjct: 1066 HQCRYFIIDQWFTKSAKSKIYEPSIWKV 1093
>gb|EEK07414.1| hypothetical protein BmurDRAFT_15280 [Brachyspira murdochii DSM
           12563]
          Length = 426

 Score = 37.6 bits (86), Expect = 1.5,   Method: Composition-based stats.
 Identities = 27/117 (23%), Positives = 41/117 (35%), Gaps = 15/117 (12%)

Query: 215 NLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHY--ILWEVLNILAINKNIEQWRQ 272
           +L DE IL +              N       +KE     IL+     +++ K + +   
Sbjct: 285 SLMDESILNY------------IDNYADYYNELKEFKSFNILYYDDKTISLYKRVSKLED 332

Query: 273 LIRDEIYLSIYNTSGNAIKEYELKYKLPTNDKVNLELRKNNITLDFYKIILNLLSNL 329
           L   EI          + K      K   ND   L L+K N   DFY  I +L+  +
Sbjct: 333 LKLAEIDNMFMTFELESQKLISPYIKDFVNDSEAL-LKKYNAPSDFYSNIDSLIFGI 388
>dbj|BAD95474.1| Cryhime1 [Paenibacillus popilliae]
          Length = 1340

 Score = 37.2 bits (85), Expect = 2.2,   Method: Composition-based stats.
 Identities = 12/47 (25%), Positives = 18/47 (38%)

Query: 271 RQLIRDEIYLSIYNTSGNAIKEYELKYKLPTNDKVNLELRKNNITLD 317
           +   +    + I   S N++     KY   T+  V  E R  N  LD
Sbjct: 11  KSYNQHGNEMQIIQPSSNSLLYSPNKYPYATDPNVIAEGRSYNNWLD 57
>ref|XP_001019375.1| hypothetical protein TTHERM_00389700 [Tetrahymena thermophila SB210]
 gb|EAR99130.1| hypothetical protein TTHERM_00389700 [Tetrahymena thermophila SB210]
          Length = 1778

 Score = 36.8 bits (84), Expect = 2.6,   Method: Composition-based stats.
 Identities = 47/229 (20%), Positives = 85/229 (37%), Gaps = 29/229 (12%)

Query: 110  KFVFNTLEGKEVCSKILQHTLGLLSLLLLTRKIRLLNFSSKLR--LVIQQLSLFRYYL-- 165
            K+  N L  +    +  +HT  L  L      I LL    K    ++I+Q S F  +L  
Sbjct: 1298 KYSMNFLYVQYGLFQFQKHTNFLFILFEFVVNIPLLIQRYKWARNILIEQTSHFLEWLNR 1357

Query: 166  ----RFGNFAINLYKIIKRFRWLREMKKLHYKDQSILFYFKNFRFFDIIEAFYNLTDELI 221
                +  NF +N+  I K+   +  M + +  +QS    +      DII           
Sbjct: 1358 KNIQKRQNFLLNMLSIDKKDEHVINMSE-NKTNQSDQSNYYFKNQKDIIHLLTG------ 1410

Query: 222  LFHKLQSMFGKKNTSHANTNRLM------TFVKEQHYILWEVLNILAINKNIEQWRQLIR 275
              H L+ +  K++    +   L         +K++  +    LN+L  + N+   R++  
Sbjct: 1411 --HDLKQV--KQSNQELDIIDLEIDEEEVNLIKQRSKLSSNNLNLLPQDMNLVGLREIDN 1466

Query: 276  DEIYLSIYNTSGNAIKEYE----LKYKLPTNDKVNLELRKNNITLDFYK 320
             +    I   SG    + E       +    DK + ++ +  I LD  K
Sbjct: 1467 KQNDKQIIKESGGNKNQIEGGLVEGNQGDQIDKKDTKIEQQLINLDLLK 1515
>ref|XP_001010669.1| hypothetical protein TTHERM_00112740 [Tetrahymena thermophila
           SB210]
 gb|EAR90424.1| hypothetical protein TTHERM_00112740 [Tetrahymena thermophila
           SB210]
          Length = 225

 Score = 36.8 bits (84), Expect = 2.6,   Method: Composition-based stats.
 Identities = 18/99 (18%), Positives = 32/99 (32%), Gaps = 2/99 (2%)

Query: 150 KLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLREMKKLHYKDQSILFYFKNFRFFDI 209
           K+  +   + + R  LR G  A NL ++I   + L   +  H K Q            D 
Sbjct: 26  KMEKLGSTMQMTRKVLRLGKPATNLMQMIISIKKLINSQ--HNKPQETKLLLITKALKDF 83

Query: 210 IEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVK 248
               Y L D  +   K+  +  +             ++ 
Sbjct: 84  FLMSYYLCDHFVWLSKINIITKEAIAKKVEILGYCFWLA 122
>ref|XP_001709765.1| Coiled-coil protein [Giardia lamblia ATCC 50803]
 gb|EDO82091.1| Coiled-coil protein [Giardia lamblia ATCC 50803]
          Length = 1076

 Score = 36.4 bits (83), Expect = 4.0,   Method: Composition-based stats.
 Identities = 25/118 (21%), Positives = 40/118 (33%), Gaps = 12/118 (10%)

Query: 212 AFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWR 271
               L ++  L H L+ M  K           M   +       E+ N+LA     ++  
Sbjct: 493 LHKELAEKTDLLHNLKLMDTKMRHDLEEAKDGM---ERASSRTTELENMLA-----QKTL 544

Query: 272 QLIRDEIYLSIY---NTSGNAIKEYELKYKLPTNDKV-NLELRKNNITLDFYKIILNL 325
           QL R    L++    NT  +A     L        +V  L L +N    D  ++   L
Sbjct: 545 QLDRKSNDLTLLMEENTKFSAQIVALLNSTNSLKLEVEQLRLERNTSYGDIKRLSAEL 602
>ref|YP_001488988.1| two-component response regulator [Arcobacter butzleri RM4018]
 gb|ABV66319.1| two-component response regulator [Arcobacter butzleri RM4018]
          Length = 214

 Score = 36.4 bits (83), Expect = 4.2,   Method: Composition-based stats.
 Identities = 18/84 (21%), Positives = 30/84 (35%), Gaps = 7/84 (8%)

Query: 198 LFYFKNFRFFDIIEAFYNLTDELI-LFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWE 256
             YF    +FD I A   + DE I L  K + +     +         T        +WE
Sbjct: 121 KIYFDENSYFDFISATITINDEEIRLTKKEKLLMNLFLSKKNQVITYETI----ENYVWE 176

Query: 257 VL--NILAINKNIEQWRQLIRDEI 278
                + +I   I + R+++  E 
Sbjct: 177 GNFVTLESIRSLIRRLRKILDKEF 200
>ref|NP_348932.1| Polysaccharide deacetylase-like protein; Xylanase/chitin
           deacetylase family enzyme [Clostridium acetobutylicum
           ATCC 824]
 gb|AAK80272.1|AE007732_6 Polysaccharide deacetylase-like protein; Xylanase/chitin
           deacetylase family enzyme [Clostridium acetobutylicum
           ATCC 824]
          Length = 289

 Score = 36.0 bits (82), Expect = 5.3,   Method: Composition-based stats.
 Identities = 16/85 (18%), Positives = 32/85 (37%), Gaps = 9/85 (10%)

Query: 271 RQLIRDEIYLSIYNTSGNAIKEYELKY---KLPTNDKVNLELRKNNITLDFYK------I 321
           +++ + +  L IY    N +K   L Y   +    D++ +   K    +D  K      I
Sbjct: 55  QEIAKKQRELKIYEDQSNTMKIPILMYHWIEDGKGDELKVSKEKFKGEMDIVKQSGYTPI 114

Query: 322 ILNLLSNLINIKGKRDKYNSELAYE 346
             + L + IN K         + ++
Sbjct: 115 SFDELYDFINNKKPFSIKPILITFD 139
>dbj|BAD15303.1| parasporal crystal protein [Paenibacillus lentimorbus]
          Length = 1332

 Score = 36.0 bits (82), Expect = 5.5,   Method: Composition-based stats.
 Identities = 13/38 (34%), Positives = 16/38 (42%)

Query: 280 LSIYNTSGNAIKEYELKYKLPTNDKVNLELRKNNITLD 317
           + I   S NA+     KY   T+  V  E R  N  LD
Sbjct: 1   MQIIQPSSNALLYSPNKYPYATDPNVIAEGRSYNNWLD 38
>ref|XP_001425614.1| hypothetical protein GSPATT00029252001 [Paramecium tetraurelia
           strain d4-2]
 emb|CAK58216.1| unnamed protein product [Paramecium tetraurelia]
          Length = 289

 Score = 36.0 bits (82), Expect = 5.5,   Method: Composition-based stats.
 Identities = 23/158 (14%), Positives = 47/158 (29%), Gaps = 10/158 (6%)

Query: 144 LLNFSSKLRLVIQQLSLFRYYLRFGNFAINLYKIIKRFRWLREMKKL-HYKDQSILFYFK 202
           L  + +KL  +    S+ R  LR+   A  L  +  +    +      HY++   + ++ 
Sbjct: 99  LRMWQNKLDALCSHFSMTRRILRWSRTAFYLQILFNKLSQQKSNHHFKHYRNLYDILFYT 158

Query: 203 NFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILA 262
                DI +  Y +         L +    +  +     R          I W +     
Sbjct: 159 YLIITDISDIIYWMC-----LIGLCNNTNLQKFTKEYAPRFYLI----ECIGWFISLCFE 209

Query: 263 INKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLP 300
              N     +    +   +        I +  +KY L 
Sbjct: 210 YRVNQIDIAKANLQKDPKNKIKIRQIQILQNLVKYALD 247
>ref|NP_722265.1| putative periplasmic sugar-binding protein [Streptococcus mutans
           UA159]
 gb|AAN59571.1|AE015020_6 putative periplasmic sugar-binding protein [Streptococcus mutans
           UA159]
          Length = 320

 Score = 35.6 bits (81), Expect = 6.9,   Method: Composition-based stats.
 Identities = 22/93 (23%), Positives = 37/93 (39%), Gaps = 13/93 (13%)

Query: 235 TSHANTNRLMTF--------VKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYN-T 285
           T     N    +        V EQH +L+     L+I K +EQ R  I++ + + I N  
Sbjct: 41  TYMTMNNDFYKYLNAEVEKNVNEQHDLLYTRDPALSIKKQVEQIRFFIKERVDVIIINPV 100

Query: 286 SGNAIKE-YELKY---KLPTNDKVNLELRKNNI 314
            GN+      LK    +      V+ + + N+ 
Sbjct: 101 DGNSKLLINSLKRARKQGIKVIAVDSQFKDNSA 133
>ref|XP_001351113.1| IBR domain protein, putative [Plasmodium falciparum 3D7]
 emb|CAB38990.1| IBR domain protein, putative [Plasmodium falciparum 3D7]
          Length = 593

 Score = 35.3 bits (80), Expect = 8.1,   Method: Composition-based stats.
 Identities = 17/139 (12%), Positives = 39/139 (28%), Gaps = 26/139 (18%)

Query: 202 KNFRFFDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNIL 261
                  ++  +    +  I  HK++             + ++  +K +  + W      
Sbjct: 470 NFSIHTQLLFLYNFCKNYNIHLHKMKFF----------EDAIIQIIKCRKILKWSYT--- 516

Query: 262 AINKNIEQWRQLIRD----------EIYLSIYNTSGNAIKEYELKYKLPTNDKVNLELRK 311
                   W+   +           E  L I  T    I   + K     +   +++   
Sbjct: 517 --YAYFSNWKSDNQKHLFEYHQGELEKNLDILQTKTEDINLTQFKNNTDNDTVRDIQQIT 574

Query: 312 NNITLDFYKIILNLLSNLI 330
             I + F+K I   + N  
Sbjct: 575 QMIDI-FFKNICEFMENNF 592
>sp|Q736X4|Y2776_BACC1 UPF0421 protein BCE_2776
          Length = 355

 Score = 35.3 bits (80), Expect = 8.3,   Method: Composition-based stats.
 Identities = 25/130 (19%), Positives = 44/130 (33%), Gaps = 17/130 (13%)

Query: 151 LRLVIQQLSLFRYYL----RFGNFAINLYKIIKRFRWLREMKKLHYKDQSILFYFKNFRF 206
             LV +QL L +  +          I       +       + +H     +         
Sbjct: 227 FLLVQKQLHLLQQIIYHIDNLARTPIETCD-WSQNEKEILRRTIHSIISILRNNCNK--- 282

Query: 207 FDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKN 266
             I E  + L DEL      Q    K + +H   N+       +  IL+EV   L+I+  
Sbjct: 283 --IDEEHFKLIDELDK----QFWNYKNDLAHCKPNQYHHHFSSESIILFEV---LSIHDM 333

Query: 267 IEQWRQLIRD 276
           +E+ +Q+   
Sbjct: 334 LEELKQIXEK 343
>ref|YP_001394859.1| KdpD [Clostridium kluyveri DSM 555]
 gb|EDK33511.1| KdpD [Clostridium kluyveri DSM 555]
          Length = 898

 Score = 35.3 bits (80), Expect = 9.0,   Method: Composition-based stats.
 Identities = 21/106 (19%), Positives = 42/106 (39%), Gaps = 21/106 (19%)

Query: 261 LAINKNIEQWRQLIRDEIYLSIYNTSGNAIKEYELKYKLPTND--------------KVN 306
           L++ K  E+  +  + +I + I            + + L T                KV 
Sbjct: 647 LSLEK--EKLNE-RQKQISMQIQQEKLRGNLLRTISHDLRTPLTSISGNAGILMGNSKVL 703

Query: 307 LELRKNNITLDFYK---IILNLLSNLINI-KGKRDKYNSELAYEII 348
            E +K  +  D Y     ++NL+ N+++I + +  K N  L  E++
Sbjct: 704 SEAQKKGLYTDIYDDSMWLINLVENILSITRIEDGKINLNLQPELL 749
>ref|ZP_02600723.1| hypothetical protein Bcer0_05480 [Bacillus cereus 03BB108]
 sp|A0REW2|Y2468_BACAH UPF0421 protein BALH_2468
          Length = 355

 Score = 35.3 bits (80), Expect = 9.3,   Method: Composition-based stats.
 Identities = 26/130 (20%), Positives = 46/130 (35%), Gaps = 17/130 (13%)

Query: 151 LRLVIQQLSLFRYYL----RFGNFAINLYKIIKRFRWLREMKKLHYKDQSILFYFKNFRF 206
             LV +QL L +  +          I       +       + +H     +  Y +    
Sbjct: 227 FLLVQKQLHLLQQIIYHIDNLARAPIETCD-WSQNEKEILRRTIHSIISILRNYCEK--- 282

Query: 207 FDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKN 266
             I E  + L DEL      Q    K + +H   N+       +  IL+EV   L+I+  
Sbjct: 283 --IDEEHFKLIDELDK----QFWTNKNDLAHCKPNQYHHHFSSESIILFEV---LSIHDM 333

Query: 267 IEQWRQLIRD 276
           +E+ +Q+   
Sbjct: 334 LEELKQIFEK 343
>ref|YP_500154.1| hypothetical protein SAOUHSC_01641 [Staphylococcus aureus subsp.
           aureus NCTC 8325]
 gb|ABD30718.1| conserved hypothetical protein [Staphylococcus aureus subsp. aureus
           NCTC 8325]
          Length = 306

 Score = 34.9 bits (79), Expect = 9.5,   Method: Composition-based stats.
 Identities = 36/190 (18%), Positives = 70/190 (36%), Gaps = 17/190 (8%)

Query: 124 KILQHTLGLLSL----LLLTRKIRLLNFSSKLRLVIQQLSLFRYYLRF--GNFAINLYKI 177
           K LQ+ L L+S+    +++     +  F      +  QLS F+  L F   +    +  +
Sbjct: 71  KTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLSSFQKTLSFFITSLPTIIVVM 130

Query: 178 IKRFRWLREMKKLHYKDQ--SILFYF--KNFRFFDIIEAF--YNLTDELILFHK--LQSM 229
           +     L  + KL Y +        F  K        + F  Y +T+EL+LF+K  +   
Sbjct: 131 LIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ 190

Query: 230 FGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKNIEQWRQLIRDEIYLSIYNTSGNA 289
                  + +++    F+ +  Y+L        + + +E+ +      I   +       
Sbjct: 191 SIVDVYINHSSDPFRQFLGK--YLLTYSEMGYGLPQILEKLKCFKPQLIKF-VLQGEKRG 247

Query: 290 IKEYELKYKL 299
             E ELK   
Sbjct: 248 KLEVELKLYS 257
>ref|YP_895262.1| hypothetical protein BALH_2468 [Bacillus thuringiensis str. Al
           Hakam]
 gb|ABK85755.1| conserved hypothetical protein [Bacillus thuringiensis str. Al
           Hakam]
          Length = 360

 Score = 34.9 bits (79), Expect = 9.8,   Method: Composition-based stats.
 Identities = 26/130 (20%), Positives = 46/130 (35%), Gaps = 17/130 (13%)

Query: 151 LRLVIQQLSLFRYYL----RFGNFAINLYKIIKRFRWLREMKKLHYKDQSILFYFKNFRF 206
             LV +QL L +  +          I       +       + +H     +  Y +    
Sbjct: 232 FLLVQKQLHLLQQIIYHIDNLARAPIETCD-WSQNEKEILRRTIHSIISILRNYCEK--- 287

Query: 207 FDIIEAFYNLTDELILFHKLQSMFGKKNTSHANTNRLMTFVKEQHYILWEVLNILAINKN 266
             I E  + L DEL      Q    K + +H   N+       +  IL+EV   L+I+  
Sbjct: 288 --IDEEHFKLIDELDK----QFWTNKNDLAHCKPNQYHHHFSSESIILFEV---LSIHDM 338

Query: 267 IEQWRQLIRD 276
           +E+ +Q+   
Sbjct: 339 LEELKQIFEK 348
  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF excluding environmental samples
  from WGS projects
    Posted date:  May 23, 2008  5:56 PM
  Number of letters in database: 883,778,997
  Number of sequences in database:  2,617,685
  
  Database: /host/Blast/data/nr_perl/nr.01
    Posted date:  May 23, 2008  5:54 PM
  Number of letters in database: 976,759,346
  Number of sequences in database:  2,761,413
  
  Database: /host/Blast/data/nr_perl/nr.02
    Posted date:  May 23, 2008  5:48 PM
  Number of letters in database: 374,670,760
  Number of sequences in database:  1,165,270
  
  Database: /host/Blast/data/nr_perl/nr.03
    Posted date:  Apr 28, 2009  5:40 PM
  Number of letters in database: 114,943,120
  Number of sequences in database:  354,819
  
Lambda     K      H
   0.310    0.151    0.412 

Lambda     K      H
   0.267   0.0464    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,420,419,712
Number of Sequences: 6899187
Number of extensions: 245255257
Number of successful extensions: 646254
Number of sequences better than 10.0: 163
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 445
Number of HSP's that attempted gapping in prelim test: 645786
Number of HSP's gapped (non-prelim): 731
length of query: 376
length of database: 2,350,152,223
effective HSP length: 136
effective length of query: 240
effective length of database: 1,411,862,791
effective search space: 338847069840
effective search space used: 338847069840
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 80 (35.2 bits)