HSD17B4 multialignment

CLUSTAL (-like) formatted alignment by MAFFT L-INS-i (v6.611b)
  
1                                                        60
GENSCAN00000095486 Equus_caballus M--------------------------CLYFVIALEMVLQQVLVEVQEVNDLGGDMKGVG
ENSMODG00000013536 Monodelphis_domestica ------------------------------------------------VNDLGGDFKGVG
ENSMMUG00000017685 Macaca_mulatta ----------------------------LGRAYALAFAERGALV---VVNDLGGDFKGVG
ENSG00000133835 Homo_sapiens M--------GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALV---VVNDLGGDFKGVG
ENSPTRG00000017168 Pan_troglodytes M--------GSPLRFDGRVVLVTGAGAGLGRAYALAFAERGALV---VVNDLGGDFKGVG
Hsd17b4 Rattus_norvegicus M--------ASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALV---VVNDLGGDFKGVG
ENSMUSG00000024507 Mus_musculus M--------ASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALV---IVNDLGGDFKGIG
ENSCAFG00000000158 Canis_familiaris M--------ASPLRFDGRVVLVTGAGGGLGRAYALAFAERGASV---VVNDLGGDFKGLG
ENSBTAG00000006978 Bos_taurus ------------------------------------------------------------
ENSXETG00000017534 Xenopus_tropicalis M-------DSQALRFDGRVVLVTGAGGGLGRTYALAFAERGASV---IVNDLGGDIKGEG
NEWSINFRUG00000152986 Takifugu_rubripes ------------LSFEGRVVLVTGAGGGLGREYALAFAERGASV---VVNDLGGNAKGGG
GSTENG00030945001 Tetraodon_nigroviridis M----------ALSFEGRVVLVTGAGGGLGREYALAFAQRGASV---VVNDLGGNTKGGG
ENSGALG00000002187 Gallus_gallus L--------SFPLSSEEKIQLIFGAQPGLGRAYALAFAERGASV---VVNDLGGDFKGYG
ENSDARG00000031873 Danio_rerio M--------SVPLRFDGKVVLVTGAGGGLGREYALAFGQRGAAV---IVNDLGGDIKGGG
ENSCING00000009223 Ciona_intestinalis N--------MSELRFDGKVVLITGAGAGLGKCYALEFAKRGASV---VVNDLGSTPGGVG
ENSANGG00000011810 Anopheles_gambiae M-VAPKENASKQLRYDGRVVVVTGAGAGLGREYALLFASRGAKV---VVNDLGGNFHGQG
CG3415 Drosophila_melanogaster M-----SSSDGKLRYDGRVAVVTGAGAGLGREYALLFAERGAKV---VVNDLGGTHSGDG
ENSAPMG00000004499 Apis_mellifera E---------EKLSFVNRVVIITGAGAGLGRTYALLFASRGASV---VVNDLGGSRDGDG
EAS01180 Tetrahymena_thermophila M---------SQIRFDNRVVIVTGAGNGLGREYALYFASKGAKV---VVNDLGVTHSGEG
M03A8.1 Caenorhabditis_elegans M----------SLRFDGKVAIVTGAGGGLGKTYALELAKRGCKV---VVNDLGGDRHGTS
DDB0201628 Dictyostelium_discoideum M----------ALNFKDKVVIVTGAGGGIGKVYALEFAKRGAKV---VVNDLGGSHTGQG
NCU08828.2 Neurospora_crassa M--------AEQLRFDGQVVVVTGAGGGLGKAYCLFFGSRGASV---VVNDLGASFKGEG
XP_746577.1 Aspergillus_fumigatus M---------SELRFDNQTVVVTGAGGGLGKAYATFFASRGANV---VVNDLGVSHSGEG
CAG79573.1 Yarrowia_lipolytica M--------SGELRYDGKVVIVTGAGGGLGKAYALFYGSRGASV---VVNDLGGDFKGDG
XP_571589.1 Cryptococcus_neoformans MAHQQPIPSADSLNFKDLVVLVTGAGSGIGRTYARFFAARGAKV---VINDV--------
NP_986606.1 Eremothecium_gossypii M----------SLTFNDRVVIITGAGGGLGREYALDYAKRGAKV---VVNDLGGTLGGSG
CAG61834.1 Candida_glabrata M--------GKDLSFNGRVVVITGAGGGLGKVYALEYAKRGAKV---VVNDLGGTLGGSG
YKR009C Saccharomyces_cerevisiae M--------PGNLSFKDRVVVITGAGGGLGKVYALAYASRGAKV---VVNDLGGTLGGSG
CAG99661.1 Kluyveromyces_lactis M----------SLEFKDRVVIITGAGGGLGRVYALEYAKRGGKV---VVNDLGR------
CAG84660.1 Debaryomyces_hansenii M---------SEISFKDKVVVVTGAGGGLGKQYCLEYAKRGAKV---VVNDLGGSLKGDG
DDB0214811 Dictyostelium_discoideum M-----------------------------------------------------------
EAS00575 Tetrahymena_thermophila M-----------------------------------------------------------
  
61                                                        120
GENSCAN00000095486 Equus_caballus KSS----LAADKVVEEIRSRGGK--AVASY--DSV-EAGEKIVKTALDAFGRI-DVVVNN
ENSMODG00000013536 Monodelphis_domestica RSS----SAADNVVEEIKKRGGK--AVANY--DSV-EAGEKVVKTALDAFGKI-DIVINN
ENSMMUG00000017685 Macaca_mulatta KGS----LAADKVVEEIRRRGGK--AVASY--DSV-EEGEKVVKTALDAFGRI-DVVVNN
ENSG00000133835 Homo_sapiens KGS----LAADKVVEEIRRRGGK--AVANY--DSV-EEGEKVVKTALDAFGRI-DVVVNN
ENSPTRG00000017168 Pan_troglodytes KGS----LAADKVVEEIRRRGGK--AVANY--DSV-EEGEKVVKTALDAFGRI-DVVVNN
Hsd17b4 Rattus_norvegicus KGS----SAADKVVEEIRRRGGK--AVANY--DSV-EAGEKLVKTALDTFGRI-DVVVNN
ENSMUSG00000024507 Mus_musculus KGS----SAADKVVAEIRRKGGK--AVANY--DSV-EAGEKLVKTALDTFGRI-DVVVNN
ENSCAFG00000000158 Canis_familiaris KGSF---AAADKVVEEIRSKGGK--AVANY--DSV-EAGEKIVRTALEAFGRI-DVVVNN
ENSBTAG00000006978 Bos_taurus --------------------------------DSV-EEGEKIVKTALDAFGRI-DIVINN
ENSXETG00000017534 Xenopus_tropicalis KSS----SAADKVVEEIRAKGGK--AVANY--DSV-EAGEKLVQTALDAFGRI-DIVVNN
NEWSINFRUG00000152986 Takifugu_rubripes KSS----AAADKVVEEIRAKGGK--AVANY--DSV-EDGEKLIQSALKEFGRI-DVVVNN
GSTENG00030945001 Tetraodon_nigroviridis KSS----AAADKVVEEIRAKGGK--AVASY--DSV-EDGEKLIQSALERFGRI-DVVVNN
ENSGALG00000002187 Gallus_gallus KSS----SAADKVVSEIRANGGK--AVPNYVTDSV-EDGEKLVKSALEAFGRIADIVINN
ENSDARG00000031873 Danio_rerio KSS----AAADKVVEEIRAAGGK--AVANY--DSV-EDGEKLIQTALDAFGRI-GAVYKQ
ENSCING00000009223 Ciona_intestinalis SSA----KVADQVVDEIRKLGGT--AVANY--DSV-EFGEKLVNTALQNFGRI-DIVINN
ENSANGG00000011810 Anopheles_gambiae KSN-----AADKVVEEIRAAGGV--AVPDY--NSV-VEGDKIVQTALENFGRI-DVLVNN
CG3415 Drosophila_melanogaster ASQ----RAADIVVDEIRKAGGE--AVADY--NSV-IDGAKVIETAIKAFGRV-DILVNN
ENSAPMG00000004499 Apis_mellifera SST----KIADSVVNEIRKNGGR--AVANY--DSV-LDGEKIVKTAIDAFGRI-DILVNN
EAS01180 Tetrahymena_thermophila TKT----NPAQKVVDEIKAAGGV--AVANT--DSV-EFGDKIVKTAIDAFGKV-DVIINN
M03A8.1 Caenorhabditis_elegans SSS----SMADKVVQEIKSAGGQ--AVANY--DSV-EFGDKIVKTAIDNFGRI-DIVINN
DDB0201628 Dictyostelium_discoideum SSS----KAADKVVEEIKAAGGT--AVANY--DSV-EDGEKIVQTAMDSFGGV-DILINN
NCU08828.2 Neurospora_crassa NST----KAADVVVNEIKAAGGK--AVANY--DSV-ENGDKIIETAIKEFGRI-DILINN
XP_746577.1 Aspergillus_fumigatus ASS----KAADVVVEEIRAAGGK--AVANY--DSV-ENGEAIIETAIKNFGRI-DVLINN
CAG79573.1 Yarrowia_lipolytica AQAGSGKRVADVVVDEIVSKGGK--AVANY--DSV-ENGDKIVETAVKAFGSV-HIVINN
XP_571589.1 Cryptococcus_neoformans -SA----EAAQAVVDEIAKGGGK--AIAAP--GSV-TDGSTIVAQAVKAFGTV-HVLINN
NP_986606.1 Eremothecium_gossypii HDT----RAADKVVEEIRKAGGT--AVANY--DTV-TDGDKIVKTAIDAFGRV-DVIVNN
CAG61834.1 Candida_glabrata HDS----KAADVVVDEIVKSGGT--AVANY--DSVNDNGEQIVETAIKAFGRI-DILINN
YKR009C Saccharomyces_cerevisiae HNS----KAADLVVDEIKKAGGI--AVANY--DSVNENGEKIIETAIKEFGRV-DVLINN
CAG99661.1 Kluyveromyces_lactis -------SAADSVVQEIKKLGGEGDAVANY--DSVSDNGAAIVETAISNFGRV-DILINN
CAG84660.1 Debaryomyces_hansenii GNS----SAADDVVEEIKKAGGI--AVADY--NNV-LDGAKIIETAVKSFGTV-HIIVNN
DDB0214811 Dictyostelium_discoideum ---------------------------------TV-------------------DV----
EAS00575 Tetrahymena_thermophila --------------------SGE--SAPQV------------------------DV----
  
121                                                        180
GENSCAN00000095486 Equus_caballus AG---------------------------------------------IIMTSSASGIYGN
ENSMODG00000013536 Monodelphis_domestica AG-ILRDRSFVRISDEDWDIIHKVHLRGSFQVTRAAWDHMKKQKFGRIIMTSSASGIYGN
ENSMMUG00000017685 Macaca_mulatta AG-ILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWDHMKKQKYGRIIMTSSASGIYGN
ENSG00000133835 Homo_sapiens AG-ILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGN
ENSPTRG00000017168 Pan_troglodytes AG-ILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGN
Hsd17b4 Rattus_norvegicus AG-ILRDRSFSRISDEDWDIIQRVHLRGSFQVTRAAWDHMKKQNYGRIIMTASASGIYGN
ENSMUSG00000024507 Mus_musculus AG-ILRDRSFSRISDEDWDIIHRVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGN
ENSCAFG00000000158 Canis_familiaris AG-ILRDSSFGRISDEDWDIIHRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASGIYGN
ENSBTAG00000006978 Bos_taurus AG-ILRDRSFSRISDEDWDKIQRVHLRGSFLVTRAAWDHMKKQKFGRIIMTSSASGIYGN
ENSXETG00000017534 Xenopus_tropicalis AG-ILRDRSFARISDADWDIIHRVHLKGAFLITRAAWNHMKNQKFGRIIMTSSAAGIYGN
NEWSINFRUG00000152986 Takifugu_rubripes AG-ILRDRSFARTSDLDWDLIHRIHLRGSFLVTRAAWDHMKKQKFGRIIMTTSAAGIYGN
GSTENG00030945001 Tetraodon_nigroviridis AG-ILRDRSFPRTSDVDWDLIHRIHLRGSFLVTRAAWDQMKKQKFGRIIMTASAAGIYGN
ENSGALG00000002187 Gallus_gallus AG-ILRDRSFVRISDEDWDIIHRIHLRGSFLVTRAAWNHMKNQKFGRIIMTSSAAGIYGN
ENSDARG00000031873 Danio_rerio SGKILRDRSFARTSDVDWDLIQRVHLRGSFLVTRAAWNHMKQQKFGRVETYST----HLN
ENSCING00000009223 Ciona_intestinalis AG-ILRDRSFMRMSDDEWDLVNKIHLRGSYSVTKAAWNHMKTQNYGRIIMTSSASGLYGN
ENSANGG00000011810 Anopheles_gambiae AG-ILRDRSLARISDEDWNLIHDVHLKGSFLTTRAAWPVMKKQNYGRIIMTSSNSGVYGN
CG3415 Drosophila_melanogaster AG-ILRDRSLVKTSEQDWNLVNDVHLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGN
ENSAPMG00000004499 Apis_mellifera AG-ILRDKSFAKMLESDWDLIQNVHLKGAFKTTQAAWPYFVKQKYGRIIMTASNSGLYGN
EAS01180 Tetrahymena_thermophila AG-ILRDITFQKMTDLDWNLIMKVHVNGTYSVTRAAWDIMRQQGYGRIINTGSGSGIYGS
M03A8.1 Caenorhabditis_elegans AG-ILRDVSFLKMTELDWDLIFKVHVKGAYAVTKAAWPYMRDQKYGRIVVTSSNAGVHGN
DDB0201628 Dictyostelium_discoideum AG-ILRDVSFGKMTDGDWDLVYRVHAKGAYKLSRAAWNHMREKNFGRIIMTSSAAGLYGN
NCU08828.2 Neurospora_crassa AG-ILRDISFKNMKDEDWDLIFKVHVKGSYKTARAAWPYFRKQKFGRVINTASAAGLFGN
XP_746577.1 Aspergillus_fumigatus AG-ILRDVSFKNMKDQDWDLINKVHTYGAYKCARAAWPHFRKQKYGRIINTASAAGLFGN
CAG79573.1 Yarrowia_lipolytica AG-ILRDISFKKMTDKDWDLVYKVHVFGAYKVTRAAWPYFRKQKYGRVISTSSAAGLYGN
XP_571589.1 Cryptococcus_neoformans AG-ILRDKSFKNMSDQDWDLVIAVHLKGAYSCTKACWPLFRQQKFGRVVNTASAAGLYGN
NP_986606.1 Eremothecium_gossypii AG-ILRDGSFAKMTEKNFSAVVDVHLNGSYKLCKAAWPYMRQQKYGRIVNTASPAGLYGN
CAG61834.1 Candida_glabrata AG-ILRDVSFAKMTEKEFSAVLDVHLTGAYRLTKAAWPYMRQQKFGRIINTASPAGLFGN
YKR009C Saccharomyces_cerevisiae AG-ILRDVSFAKMTEREFASVVDVHLTGGYKLSRAAWPYMRSQKFGRIINTASPAGLFGN
CAG99661.1 Kluyveromyces_lactis AG-ILRDSSFAKMSEKQFQQVIDVHLNGAFKLTRAAWPHMRKQKFGRIINTCSPAGLYGN
CAG84660.1 Debaryomyces_hansenii AG-VLRDASFKKMQEKDFKFVIDVHLNGAYKVTQAAWPYFRKQQYGRVLNTASPAGLYGN
DDB0214811 Dictyostelium_discoideum ------------------------------------------------------------
EAS00575 Tetrahymena_thermophila ------------------------------------------------------------
  
181                                                        240
GENSCAN00000095486 Equus_caballus FGQANYSAAKLGLLGLSNTLAIEGKKNNIHCNTIAPQAGSRLTQTVFPE-----------
ENSMODG00000013536 Monodelphis_domestica FGQANYSAAKLGLAGLSNTLAIEGRKFNIHCNTIAPTAGSRMTESVMPQDLVDALKPD-Y
ENSMMUG00000017685 Macaca_mulatta FGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPE-Y
ENSG00000133835 Homo_sapiens FGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPE-Y
ENSPTRG00000017168 Pan_troglodytes FGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPE-Y
Hsd17b4 Rattus_norvegicus FGQANYSAAKLGLLGLANTLVIEGRKNNIHCNTIAPNAGSRMTETVMPEDLVEALKPE-Y
ENSMUSG00000024507 Mus_musculus FGQANYSAAKLGILGLCNTLAIEGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPE-Y
ENSCAFG00000000158 Canis_familiaris FGQASYSAAKLGLLGFSNTLAIEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALKPD-Y
ENSBTAG00000006978 Bos_taurus FGQANYCAAKLGLLGLSNCLAVEGKKNNIHCNTIAPTAGSRMTQSILPEDLVEALKPD-Y
ENSXETG00000017534 Xenopus_tropicalis FGQANYSAAKLGLVGLSNTLAIEGTKYNIHSNCIAPTAGSRLTQTVMPQDLLDALKPE-Y
NEWSINFRUG00000152986 Takifugu_rubripes FGQSNYSAAKLGLLGLANTLAIEGSKHNIYCNTIAPVAGSRLTETVMPPDLVASLKPE-Y
GSTENG00030945001 Tetraodon_nigroviridis FGQSNYSSAKLGLLGLANTLAIEGRKYNIHCNTVAPVAGSRLTETVMPPDLVASLKPE-Y
ENSGALG00000002187 Gallus_gallus FGQANYSAAKLGLLGLSNTIAIEGRKYNIHCNTIAPTAGSRLTQTVMPQDLIDAFKPE-Y
ENSDARG00000031873 Danio_rerio TQTQQNTHEHLGAIPESRLCDIHGVSRWI-TSTLVPKSES-LYNECMNKDLIFTLQSNIY
ENSCING00000009223 Ciona_intestinalis YGQSNYSAAKMGLIGFANTLKLEGKKYNISVNTIAPNALTRLTEGLIPPEVGKDLKIE-Y
ENSANGG00000011810 Anopheles_gambiae FGQANYSAAKLGLVGLANTVAIEGAKNNIQCNVIVPTAASRMTEGILPEILFNELKPK-L
CG3415 Drosophila_melanogaster FGQVNYTAAKMGLIGLANTVAIEGARNNVLCNVIVPTAASRMTEGILPDILFNELKPK-L
ENSAPMG00000004499 Apis_mellifera FGQANYSAAKMGLIGLTNTLAIEGKQKNIHTNVIIPTAASRLTEDILPPDFFKELKPE-L
EAS01180 Tetrahymena_thermophila FGQANYSTAKLGIHGLTLTLAKEGEKRNIRVNTIAPIAASRMTETVLPKEALANLDPK-H
M03A8.1 Caenorhabditis_elegans FGQANYAAAKSALIGLSNSLAQEGAKYNILANTLVPTAGSRLTETVMPQNLVDALKPD-Y
DDB0201628 Dictyostelium_discoideum FGQANYGSMKMALVGLSNTLAQEGKSKNIHCNTIAPIAASRLTESVMPPEILEQMKPD-Y
NCU08828.2 Neurospora_crassa FGQANYSAAKLGMVGFTETLAKEGLKYNIISNVIAPIAASRMTETVMPPDLLALMKPE-W
XP_746577.1 Aspergillus_fumigatus FGQANYSAAKLGQVGFTETLAKEGAKYNIIANVIAPIAASRMTATIMPPEVLENLKPD-W
CAG79573.1 Yarrowia_lipolytica FGQTNYSAAKLALVGFGETLAKEGAKYNITSNVIAPLAASRMTETVMPEDILKLLKPE-Y
XP_571589.1 Cryptococcus_neoformans MGQANYSAAKMGLIGFTRTLAREGAKYDIKVNVIAPMAASAMTETIMPPDMLKGLKPE-F
NP_986606.1 Eremothecium_gossypii FGQTNYSAAKLGLVGLSETLAKEGHKYNIKVNVIAPIARSRMTEGLLPDHVIRVMGPE-K
CAG61834.1 Candida_glabrata FGQANYSAAKLGLVGFAETLAKEGYKYNINVNSIAPLARSRMTENVLPPHILKQLGPE-K
YKR009C Saccharomyces_cerevisiae FGQANYSAAKMGLVGLAETLAKEGAKYNINVNSIAPLARSRMTENVLPPHILKQLGPE-K
CAG99661.1 Kluyveromyces_lactis FGQANYSAAKLGLLGFGESLAKEGYKYNINVNSIAPLARSAMTENVIPANILKELGPE-K
CAG84660.1 Debaryomyces_hansenii FGQANYSAAKLGLASFAETLAKEGEKYNIKANTIAPLARSRMTESILPPPVLEQLSPA-K
DDB0214811 Dictyostelium_discoideum ------------------------------------------------------------
EAS00575 Tetrahymena_thermophila ------------------------------------------------------------
  
241                                                        300
GENSCAN00000095486 Equus_caballus ------------------------------V-RWERTLGALVRQR---------------
ENSMODG00000013536 Monodelphis_domestica VAPLVLWLCH-ESCEENGGLFEVGAGWIGKL-RWERTLGAIVRQK---------------
ENSMMUG00000017685 Macaca_mulatta VAPLVLWLCH-ESCEE-GGLFVGAGWIGKL-RWERTLGAIVRQK---------------
ENSG00000133835 Homo_sapiens VAPLVLWLCH-ESCEENGGLFEVGAGWIGKL-RWERTLGAIVRQK---------------
ENSPTRG00000017168 Pan_troglodytes VAPLVLWLCH-DSCEENGGLFEVGAGWIGKL-RWERTLGAIVRQK---------------
Hsd17b4 Rattus_norvegicus VAPLVLWLCH-ESCEENGGLFEVGAGWIGKL-RWERTLGAIVRKR---------------
ENSMUSG00000024507 Mus_musculus VAPLVLWLCH-ESCEENGGLFEVGAGWIGKL-RWERTLGAIVRKR---------------
ENSCAFG00000000158 Canis_familiaris VAPLVLWLCH-ESCEENGSLFEVISPFLLSLIRWERTLGAIVRQK---------------
ENSBTAG00000006978 Bos_taurus VAPLVLWLCH-ESCEENGGLFEVGAGWIGKL-RWERSLGALVRQR---------------
ENSXETG00000017534 Xenopus_tropicalis VTPLVLWLCH-ESCQETGSLFEVGAGWVGKL-RWERSLGAIIRQK---------------
NEWSINFRUG00000152986 Takifugu_rubripes VAPLVLWLCH-EQCQENGGLFEVGAGWVGKL-RWERSQGQIMRQK---------------
GSTENG00030945001 Tetraodon_nigroviridis VAPLVLWLCH-EQCQENGGLFEVGAGWVGKL-RWERSRGQIVRQK---------------
ENSGALG00000002187 Gallus_gallus VAPLVLWLCH-ETCMENGSLFEVGAGWIGKR-KFSRCYVRILLIL---------------
ENSDARG00000031873 Danio_rerio IMKSCVCVCV-CVCYVIVLL----------V-RWERSLGRIVRQK---------------
ENSCING00000009223 Ciona_intestinalis IMPLVIYLCH-ESCLETGGVFEVSGGHVCKL-RWERTKGAVLREE---------------
ENSANGG00000011810 Anopheles_gambiae IAPVVAYLCH-ESCEDTGAIIESAAGWATKV-HFVRGRGCVLRTS---------------
CG3415 Drosophila_melanogaster IAPVVAYLCH-ESCEDNGSYIESAAGWATKL-HMVRGKGAVLRPS---------------
ENSAPMG00000004499 Apis_mellifera IAPVVVWLCH-EKCMENGSIIESALGWAGKC-HVIRSSGSTLRQD---------------
EAS01180 Tetrahymena_thermophila IVPLVGYLAH-ESCEETGSLFEIAAGFIAKL-RWQRAAGALF------------------
M03A8.1 Caenorhabditis_elegans VTPLVTYMVH-DSFEESGKVFEAGAGWYGTI-QYYKSKGKVISHA---------------
DDB0201628 Dictyostelium_discoideum IVPLVLYLCH-QDTTETGGVFEVGAGWVSKV-RLQRSAGVYMK-----------------
NCU08828.2 Neurospora_crassa VVPLVAVLVHKNNTSETGSIFEVGGGHVAKL-RWERSSGLLLKAD-ESYTPGAIIKKWDQ
XP_746577.1 Aspergillus_fumigatus VVPLVAVLVHPSNTTESGSIFEVGGGHMAKL-RWERAKGALLKTD-ASLTPGAIARKWKD
CAG79573.1 Yarrowia_lipolytica VVPLVGYLTH-DSVTESYGIYEVGAGYMAKI-RWERGNGAVFKGD-DTFTPSAILKRWDE
XP_571589.1 Cryptococcus_neoformans IAPFVGILTARNGPDVSGRIFELGAGFFSEV-RWERSRGAIWKPD-DTFTPSAVAEKWAE
NP_986606.1 Eremothecium_gossypii VVPMVVYLTH-ENTEVTNSIFEPGAGYYTQV-RWERSSGGLFNPDEKTFTPEAILHKFPE
CAG61834.1 Candida_glabrata IAPLVLFLTH-ESTKVTNSIFELAAGFYGQI-RWERSAGQIFNPNPETYTPEAILNKWTD
YKR009C Saccharomyces_cerevisiae IVPLVLYLTH-ESTKVSNSIFELAAGFFGQL-RWERSSGQIFNPDPKTYTPEAILNKWKE
CAG99661.1 Kluyveromyces_lactis IAPLILYLTH-ENTKVTNNIFELAAGFYSQI-RWERSSGELFHPNVETLTPETILPKFNK
CAG84660.1 Debaryomyces_hansenii VAPLVLYLTS-DANELSGQIFEVAAGFFGQI-RWERSGGALFKPD-ETFTAEAVAKRFNE
DDB0214811 Dictyostelium_discoideum ------------------------------------------------------------
EAS00575 Tetrahymena_thermophila ------------------------------------------------------------
  
301                                                        360
GENSCAN00000095486 Equus_caballus ------------------------------------------------------------
ENSMODG00000013536 Monodelphis_domestica ------------------------------------------------------------
ENSMMUG00000017685 Macaca_mulatta ------------------------------------------------------------
ENSG00000133835 Homo_sapiens ------------------------------------------------------------
ENSPTRG00000017168 Pan_troglodytes ------------------------------------------------------------
Hsd17b4 Rattus_norvegicus ------------------------------------------------------------
ENSMUSG00000024507 Mus_musculus ------------------------------------------------------------
ENSCAFG00000000158 Canis_familiaris ------------------------------------------------------------
ENSBTAG00000006978 Bos_taurus ------------------------------------------------------------
ENSXETG00000017534 Xenopus_tropicalis ------------------------------------------------------------
NEWSINFRUG00000152986 Takifugu_rubripes ------------------------------------------------------------
GSTENG00030945001 Tetraodon_nigroviridis ------------------------------------------------------------
ENSGALG00000002187 Gallus_gallus ------------------------------------------------------------
ENSDARG00000031873 Danio_rerio ------------------------------------------------------------
ENSCING00000009223 Ciona_intestinalis ------------------------------------------------------------
ENSANGG00000011810 Anopheles_gambiae ------------------------------------------------------------
CG3415 Drosophila_melanogaster ------------------------------------------------------------
ENSAPMG00000004499 Apis_mellifera ------------------------------------------------------------
EAS01180 Tetrahymena_thermophila ------------------------------------------------------------
M03A8.1 Caenorhabditis_elegans ------------------------------------------------------------
DDB0201628 Dictyostelium_discoideum ------------------------------------------------------------
NCU08828.2 Neurospora_crassa VTDFSN--------PQYPTGPNDFLALLEESLKLGP-NDPG--EKVDFKGRVALVTGGGA
XP_746577.1 Aspergillus_fumigatus VYDYSQ--------PEYPIGPADFMTLLENGMKTPS-APAG--EEPDLKGKVALVTGGGN
CAG79573.1 Yarrowia_lipolytica VTSFES--------PTYPNGPADFFKYAEESVKRPE-NPQG--PTVSFKDQVVIVTGAGA
XP_571589.1 Cryptococcus_neoformans AQDFKG--------AEHPLNTED--------------GDMLSSPPVEFKGKTVIITGSGA
NP_986606.1 Eremothecium_gossypii VLDFKDK---PFKAVEHPYQLADYNDLISKARQLPP-NEQGSVQVKSLKDKVVIITGAGA
CAG61834.1 Candida_glabrata ITDFKDK---PFNKVQHPIMLSDYNDLITKAKKLPENNDQGSIKITSLKDKVVIITGAGG
YKR009C Saccharomyces_cerevisiae ITDYRDK---PFNKTQHPYQLSDYNDLITKAKKLPP-NEQGSVKIKSLCNKVVVVTGAGG
CAG99661.1 Kluyveromyces_lactis IIEFKDK---PFNKVQHPIELSNYNDLITKARELPE-NKNGPIPIKSLRGKVVIITGSGS
CAG84660.1 Debaryomyces_hansenii IMDFDDSKKPELLKNQHPFMLNDYKSLITAANKLPA-NDVSGAPTVSLKGKVVLITGAGA
DDB0214811 Dictyostelium_discoideum ------------------------------------------------------------
EAS00575 Tetrahymena_thermophila ------------------------------------------------------------
  
361                                                        420
GENSCAN00000095486 Equus_caballus ------------------------------------------------------------
ENSMODG00000013536 Monodelphis_domestica ------------------------------------------------------------
ENSMMUG00000017685 Macaca_mulatta ------------------------------------------------------------
ENSG00000133835 Homo_sapiens ------------------------------------------------------------
ENSPTRG00000017168 Pan_troglodytes ------------------------------------------------------------
Hsd17b4 Rattus_norvegicus ------------------------------------------------------------
ENSMUSG00000024507 Mus_musculus ------------------------------------------------------------
ENSCAFG00000000158 Canis_familiaris ------------------------------------------------------------
ENSBTAG00000006978 Bos_taurus ------------------------------------------------------------
ENSXETG00000017534 Xenopus_tropicalis ------------------------------------------------------------
NEWSINFRUG00000152986 Takifugu_rubripes ------------------------------------------------------------
GSTENG00030945001 Tetraodon_nigroviridis ------------------------------------------------------------
ENSGALG00000002187 Gallus_gallus ------------------------------------------------------------
ENSDARG00000031873 Danio_rerio ------------------------------------------------------------
ENSCING00000009223 Ciona_intestinalis ------------------------------------------------------------
ENSANGG00000011810 Anopheles_gambiae ------------------------------------------------------------
CG3415 Drosophila_melanogaster ------------------------------------------------------------
ENSAPMG00000004499 Apis_mellifera ------------------------------------------------------------
EAS01180 Tetrahymena_thermophila ------------------------------------------------------------
M03A8.1 Caenorhabditis_elegans ------------------------------------------------------------
DDB0201628 Dictyostelium_discoideum ------------------------------------------------------------
NCU08828.2 Neurospora_crassa GIGRAYCLAFARAGASVVVNDLV--NPDDVVNEIKKMGGK--AVGAKFS-AEDGDAVVKA
XP_746577.1 Aspergillus_fumigatus GLGRSYCLLFAKLGASVVVNDLV--DPEPVVQEIKKMGGK--AVGNKAS-CEDGDAVVKT
CAG79573.1 Yarrowia_lipolytica GIGRAYSHLLAKLGAKVVVNDFG--NPQKVVDEIKALGGI--AVADKNN-VIHGEKVVQT
XP_571589.1 Cryptococcus_neoformans GLGRAYALMFGKLGANLVINDLSKENAEKVVQEVKAAGGQ--AVAAVCS-AEEGETIVKA
NP_986606.1 Eremothecium_gossypii GLGRSHALWFAKYGARVVVNDLK--GADGVVAEINSQYGEGRAVADSHNIVTDAAAVVET
CAG61834.1 Candida_glabrata GLGKSHALWFAKYGARVVVNDIK--DPNTVVNEINSKYGEGRAIPDTHNVVTEANQVIET
YKR009C Saccharomyces_cerevisiae GLGKSHAIWFARYGAKVVVNDIK--DPFSVVEEINKLYGEGTAIPDSHDVVTEAPLIIQT
CAG99661.1 Kluyveromyces_lactis GLGKSHAQWFARYGAKVVINDIR--DPSAVVDEINKKYGSGSAVADTHDIVKEAQQVVQT
CAG84660.1 Debaryomyces_hansenii GLGRDYALWFAKYGAKVVVNDFK--DPSKVVDEIIKSGGE--AHGDKHDVASDSQAIIDN
DDB0214811 Dictyostelium_discoideum ------------------------------------------------------------
EAS00575 Tetrahymena_thermophila ------------------------------------------------------------
  
421                                                        480
GENSCAN00000095486 Equus_caballus ------------------------------------------------------------
ENSMODG00000013536 Monodelphis_domestica ------------------------------------------------------------
ENSMMUG00000017685 Macaca_mulatta ------------------------------------------------------------
ENSG00000133835 Homo_sapiens ------------------------------------------------------------
ENSPTRG00000017168 Pan_troglodytes ------------------------------------------------------------
Hsd17b4 Rattus_norvegicus ------------------------------------------------------------
ENSMUSG00000024507 Mus_musculus ------------------------------------------------------------
ENSCAFG00000000158 Canis_familiaris ------------------------------------------------------------
ENSBTAG00000006978 Bos_taurus ------------------------------------------------------------
ENSXETG00000017534 Xenopus_tropicalis ------------------------------------------------------------
NEWSINFRUG00000152986 Takifugu_rubripes ------------------------------------------------------------
GSTENG00030945001 Tetraodon_nigroviridis ------------------------------------------------------------
ENSGALG00000002187 Gallus_gallus ------------------------------------------------------------
ENSDARG00000031873 Danio_rerio ------------------------------------------------------------
ENSCING00000009223 Ciona_intestinalis ------------------------------------------------------------
ENSANGG00000011810 Anopheles_gambiae ------------------------------------------------------------
CG3415 Drosophila_melanogaster ------------------------------------------------------------
ENSAPMG00000004499 Apis_mellifera ------------------------------------------------------------
EAS01180 Tetrahymena_thermophila ------------------------------------------------------------
M03A8.1 Caenorhabditis_elegans ------------------------------------------------------------
DDB0201628 Dictyostelium_discoideum ------------------------------------------------------------
NCU08828.2 Neurospora_crassa AIDAFGRVDIVVNNAGILRDKAFHNMDDSLWDPVMNVHARGTYKVTKAAWPYFLKQKYGR
XP_746577.1 Aspergillus_fumigatus AIDAFGRIDILVNNAGILRDKAFTNMNDDLWNAVINVHLRGTYKVTKAAWPHMLKQKYGR
CAG79573.1 Yarrowia_lipolytica AIDAFGAVHAVVNNAGILRDKSFANMDDEMWQLIFDVHLNGTYSVTKAAWPHFLKQKYGR
XP_571589.1 Cryptococcus_neoformans AVDAFGTVHVLVANAGILRDKAFVNMDEKMWDQVIQVHMRGTFKIIKAVWPIFQKQKYGR
NP_986606.1 Eremothecium_gossypii AMKAFERVDVLVNNAGILRDRSFVKMTDDEWNSVLQVHLLSVFALSKAVWPIFMQQRSGV
CAG61834.1 Candida_glabrata AMKAYGRVDVLVNNAGILRDRSFLKMTDQEWFAVVQVHLYSTFLLSKAVWPIFLKQKGGH
YKR009C Saccharomyces_cerevisiae AISKFQRVDILVNNAGILRDKSFLKMKDEEWFAVLKVHLFSTFSLSKAVWPIFTKQKSGF
CAG99661.1 Kluyveromyces_lactis AVDKFGRVDILVNNAGILRDRSFAKMTEDEWNAVINVHLFSTFALSKAVWPIFLKQKSGY
CAG84660.1 Debaryomyces_hansenii VINKYGTIDVLVNNAGVLRDKSFAKMSDADWEIVQKVHLFGTFNLVRLAWPHFLEKKSGR
DDB0214811 Dictyostelium_discoideum ------------------------------------------------------------
EAS00575 Tetrahymena_thermophila ------------------------------------------------------------
  
481                                                        540
GENSCAN00000095486 Equus_caballus ------------------------------------------------------------
ENSMODG00000013536 Monodelphis_domestica ------------------------------------------------------------
ENSMMUG00000017685 Macaca_mulatta ------------------------------------------------------------
ENSG00000133835 Homo_sapiens ------------------------------------------------------------
ENSPTRG00000017168 Pan_troglodytes ------------------------------------------------------------
Hsd17b4 Rattus_norvegicus ------------------------------------------------------------
ENSMUSG00000024507 Mus_musculus ------------------------------------------------------------
ENSCAFG00000000158 Canis_familiaris ------------------------------------------------------------
ENSBTAG00000006978 Bos_taurus ------------------------------------------------------------
ENSXETG00000017534 Xenopus_tropicalis ------------------------------------------------------------
NEWSINFRUG00000152986 Takifugu_rubripes ------------------------------------------------------------
GSTENG00030945001 Tetraodon_nigroviridis ------------------------------------------------------------
ENSGALG00000002187 Gallus_gallus ------------------------------------------------------------
ENSDARG00000031873 Danio_rerio ------------------------------------------------------------
ENSCING00000009223 Ciona_intestinalis ------------------------------------------------------------
ENSANGG00000011810 Anopheles_gambiae ------------------------------------------------------------
CG3415 Drosophila_melanogaster ------------------------------------------------------------
ENSAPMG00000004499 Apis_mellifera ------------------------------------------------------------
EAS01180 Tetrahymena_thermophila ------------------------------------------------------------
M03A8.1 Caenorhabditis_elegans ------------------------------------------------------------
DDB0201628 Dictyostelium_discoideum ------------------------------------------------------------
NCU08828.2 Neurospora_crassa VLNTTSTSGIYGNFGQANYSAAKCAILGFSRAIALEGAKYNIYVNTIAPNAGTAMTKTIL
XP_746577.1 Aspergillus_fumigatus IVNTTSTSGIYGNFGQANYAAAKLGILGFSRALAIEGAKYNIKVNTIAPNAGTNMTRTIM
CAG79573.1 Yarrowia_lipolytica VINTTSTSGIYGNFGQANYSAAKAGILGFSRALAREGEKYNILVNTIAPNAGTAMTASVF
XP_571589.1 Cryptococcus_neoformans IITTASPNGIYGTVGQANYSTAKAGIIGLTRTLAIEGSRYGIQVNCIAPRAATAMTATVW
NP_986606.1 Eremothecium_gossypii IVNTTSTSGIYGNFGQANYSAAKAAVLGFSKSLAIEGAKRGIRVYVIAPHAFTNMTKTIF
CAG61834.1 Candida_glabrata IINTTSTSGIYGNFGQANYAAAKAAILGFSRTIAVEGAKRGIRVNIIAPHAETAMTKTIF
YKR009C Saccharomyces_cerevisiae IINTTSTSGIYGNFGQANYAAAKAAILGFSKTIALEGAKRGIIVNVIAPHAETAMTKTIF
CAG99661.1 Kluyveromyces_lactis IINTTSTSGIYGNFGQCNYAAAKAAILGFSRTLALEGTKRGITVNVIAPHAETAMTKTIF
CAG84660.1 Debaryomyces_hansenii VINITSTSGIYGNFGQANYASAKAAIIGLSRTLAIEGAKNNIKVNAVAPHAETAMTLTIF
DDB0214811 Dictyostelium_discoideum ------------------------------------------------------------
EAS00575 Tetrahymena_thermophila ------------------------------------------------------------
  
541                                                        600
GENSCAN00000095486 Equus_caballus ------------------------------------------------------------
ENSMODG00000013536 Monodelphis_domestica ------------------------------------------------------------
ENSMMUG00000017685 Macaca_mulatta ------------------------------------------------------------
ENSG00000133835 Homo_sapiens ------------------------------------------------------------
ENSPTRG00000017168 Pan_troglodytes ------------------------------------------------------------
Hsd17b4 Rattus_norvegicus ------------------------------------------------------------
ENSMUSG00000024507 Mus_musculus ------------------------------------------------------------
ENSCAFG00000000158 Canis_familiaris ------------------------------------------------------------
ENSBTAG00000006978 Bos_taurus ------------------------------------------------------------
ENSXETG00000017534 Xenopus_tropicalis ------------------------------------------------------------
NEWSINFRUG00000152986 Takifugu_rubripes ------------------------------------------------------------
GSTENG00030945001 Tetraodon_nigroviridis ------------------------------------------------------------
ENSGALG00000002187 Gallus_gallus ------------------------------------------------------------
ENSDARG00000031873 Danio_rerio ------------------------------------------------------------
ENSCING00000009223 Ciona_intestinalis ------------------------------------------------------------
ENSANGG00000011810 Anopheles_gambiae ------------------------------------------------------------
CG3415 Drosophila_melanogaster ------------------------------------------------------------
ENSAPMG00000004499 Apis_mellifera ------------------------------------------------------------
EAS01180 Tetrahymena_thermophila ------------------------------------------------------------
M03A8.1 Caenorhabditis_elegans ------------------------------------------------------------
DDB0201628 Dictyostelium_discoideum ------------------------------------------------------------
NCU08828.2 Neurospora_crassa PE-ELVQAFKPDYVAPLVLALCSDKVPKK----PTGGLYEVGSGWCGQTRWQRSGGHGFP
XP_746577.1 Aspergillus_fumigatus PE-EMVQAFKPDYVAPMVALLCSDMCPEP----SSKGLYECGSGWFSSTRWQRSGGHGFP
CAG79573.1 Yarrowia_lipolytica TE-EMLELFKPDFIAPITVLLASDQAP------VTGDLFETGSAWIGQTRWQRAGGKAFN
XP_571589.1 Cryptococcus_neoformans PK-ELMEIFKPETVAPVVGYLAAEGCA------DTGTFYEVFGGYVAQMRWQRTYGAVFP
NP_986606.1 Eremothecium_gossypii GETEIKSSFEPSQVSPFVVLLASNEFARKYRR-SVGSLFEVGGGWIGHTRWQRAKGAV--
CAG61834.1 Candida_glabrata SEKELANHFDASQVSPLVVLLASDELQRTNKKGVNGQLFEVGGGWVGQTRWQRAAGYV-C
YKR009C Saccharomyces_cerevisiae SEKELSNHFDASQVSPLVVLLASEELQKYSGRRVIGQLFEVGGGWCGQTRWQRSSGYV-S
CAG99661.1 Kluyveromyces_lactis SSKELNNHFDPGFVSPFVVLLCSDELQELGKNRVKGLLFEVGGGWCGLTRWQRSRGIV--
CAG84660.1 Debaryomyces_hansenii NE-DDKNLFHPDQVAPLLVYLASDDVP------VTGELFEVGGGWIGNTRWQRAKGAV-S
DDB0214811 Dictyostelium_discoideum ------------------------------------------------------------
EAS00575 Tetrahymena_thermophila ------------------------------------------------------------
  
601                                                        660
GENSCAN00000095486 Equus_caballus -NQPMTPEAVKANWKKICDFG--SVSNPQTIQ-----ESTGGIIGLVSKMDSNGGVSTNH
ENSMODG00000013536 Monodelphis_domestica -NQPMTPEAVKANWRKICDFE--NANHPQTIQ-----ESTASVIEVLNKIDSQGGVSMNH
ENSMMUG00000017685 Macaca_mulatta -NHPMTPEAVKANWKKICDFE--NASKPQSIQ-----ESTGSIIEVLSKIDSE-GVSANH
ENSG00000133835 Homo_sapiens -NHPMTPEAVKANWKKICDFE--NASKPQSIQ-----ESTGSIIEVLSKIDSEGGVSANH
ENSPTRG00000017168 Pan_troglodytes -NHPMTPEAVKANWKKICDFE--NASKPQSIQ-----ESTGSIIEVLSKIDSEGGVSANH
Hsd17b4 Rattus_norvegicus -NQPMTPEAVRDNWVKICDFS--NASKPKSIQ-----ESTGGIIEVLHKIDSE-GISQNH
ENSMUSG00000024507 Mus_musculus -NQPMTPEAVRDNWEKICDFS--NASKPQTIQ-----ESTGGIVEVLHKVDSE-GISPNR
ENSCAFG00000000158 Canis_familiaris -NQPVTPEAVKANWKKICDFD--NATKPQSIQ-----ESVASLIGVVNTIDSDGGVSTNH
ENSBTAG00000006978 Bos_taurus -TQPMTPEAVKANWTKICDFD--NATKPKSIQ-----ESIGSIVEALNKINSGGEVSANP
ENSXETG00000017534 Xenopus_tropicalis -NRPMTPEAVRDEWAKISDFD--NADKPQTIQ-----DSINPLYQVLSQTDSEKGMSMNP
NEWSINFRUG00000152986 Takifugu_rubripes -SRPMTPEAVRDQWDKICDFT--DATKPTTIQ-----GQHALGSITVCYIHMGKHSHKQ-
GSTENG00030945001 Tetraodon_nigroviridis -NRAMTPEAVRDGWDRICDFT--DATKPSSVQ-----ESLQAFVSVLSQVDAGGQVEASP
ENSGALG00000002187 Gallus_gallus -STCASCCSMEEKWDKTLDFW--SKYKPFHLQEFLSLESISVLNDALSQIESQGSISMNS
ENSDARG00000031873 Danio_rerio -SECVTPEAVRDAWRDICDFT--NATKPASIQ-----ESLQTLVEVLSRVEDERKIGANP
ENSCING00000009223 Ciona_intestinalis -GKPMLPEDIKKNWEQVVDFS--EREVLETIG-----DSVMAGVSAVQRVQAGD------
ENSANGG00000011810 Anopheles_gambiae IDEDVSPEYVQQVWNRVTDMS--EAKRLNAIG-----EASLSLVGVLEKLRDGQN-----
CG3415 Drosophila_melanogaster LDDPVTIEYVKDVWSNVTDMS--KAKHLGAIA-----EASGTLLEVLEKLKEGGG-----
ENSAPMG00000004499 Apis_mellifera LSSEITPEDVENKWQVITDMS--NAKHFNSIE-----EVTGEFMTTIETTKSENS-----
EAS01180 Tetrahymena_thermophila -DLPYTAEEVRDRWNTICDFEK-NPEYPTATS-----DTFAKVNENVERIQLKRE-----
M03A8.1 Caenorhabditis_elegans -----SADDIAKNWSTITNMN--GAEYIGTIT-----EQSARLVSILEEHEASSGSS---
DDB0201628 Dictyostelium_discoideum ---DLTPEKIKDNWAQIESFD--NPSYPTSAS-----ESVSGILAAVNSKPAD-------
NCU08828.2 Neurospora_crassa VDVPLTPEEVVKHWNDIVTFDS-RADHPEKAS-----DSIEKIMANMENRVGEGKS----
XP_746577.1 Aspergillus_fumigatus VDVKLTPETVLKNWKQITDFDDGRADHPQDSQ-----AGTEKVMANMSNRSG--------
CAG79573.1 Yarrowia_lipolytica TKKGVTPEMVRDSWAKIVDFDDGNSTHPTTPS-----ESTTQILENIFNVPDEEVEETAL
XP_571589.1 Cryptococcus_neoformans NDKDISPEDILSKWKEIVTFDD-RATNPSSGV-----EALQQIVENFNNTSSIVHDEV--
NP_986606.1 Eremothecium_gossypii SLELATAEFIRDNWATITDFS--KPSYPASID-----AAGNDMMKAI-------------
CAG61834.1 Candida_glabrata LEDNVTPEALKENWKQVVNFSG-HTTNPASTE-----QSSMGILQAVQ------------
YKR009C Saccharomyces_cerevisiae IKETIEPEEIKENWNHITDFSR-NTINPSSTE-----ESSMATLQAVQ------------
CAG99661.1 Kluyveromyces_lactis -NSDATPEYLAEHWKELTDFSK-GTMNPSSTQ-----ESSMAILQSV-------------
CAG84660.1 Debaryomyces_hansenii KDEHTAPEFVRDHIKDVIDFST-GTFNPRSTE-----DSSMAILSAVGDDDDDEDDEDDD
DDB0214811 Dictyostelium_discoideum ------------------------------------------------------------
EAS00575 Tetrahymena_thermophila ------------------------------------------------------------
  
661                                                        720
GENSCAN00000095486 Equus_caballus T-SHAASTATSGF--VGAIGQKLPSFSSTYTELEAIMYALGVGASIK--EPKDMKFIYEG
ENSMODG00000013536 Monodelphis_domestica T-SQAASATTAAF--TTAIGYKLPPRTFSYTELEAIMYALGVGASVK--NPENLKFVYEG
ENSMMUG00000017685 Macaca_mulatta T-SHATSTATSGF--AGAIGQKLPPFSYAYTELEAIMYALGVGASIK--DPKDLKFVYEG
ENSG00000133835 Homo_sapiens T-SRATSTATSGF--AGAIGQKLPPFSYAYTELEAIMYALGVGASIK--DPKDLKFIYEG
ENSPTRG00000017168 Pan_troglodytes T-SRATSTATSGF--AGAIGQKLPPFSYAYTELEAIMYALGVGASIK--DPKDLKFIYEG
Hsd17b4 Rattus_norvegicus T-GQVASADASGF--AGVVGHKLPSFSSSYTELQCIMYALGVGASVK--NPKDLKFVYEG
ENSMUSG00000024507 Mus_musculus T-SHAAPAATSGF--VGAVGHKLPSFSSSYTELQSIMYALGVGASVK--NPKDLKFVYEG
ENSCAFG00000000158 Canis_familiaris T-SHAASTATSEF--AGAIGHKFPPFSSAYTELETIMYALGVGASVK--EPKDMKFIYEG
ENSBTAG00000006978 Bos_taurus T-SRATSATTSEF--ARAIGHKFPPLYSSYAELDTIMYALGVGASIK--EPKDMKFIYEG
ENSXETG00000017534 Xenopus_tropicalis T-SQGTSLSTSSIDPVKAIGQKLPLTTYTYSHLEPILYALGVGMSTR--DPDHLKFLYEG
NEWSINFRUG00000152986 Takifugu_rubripes ---------------ALAVGQKLPVSTFNFNHTQCILYALGVGMSTK--DPNHLRFLYEG
GSTENG00030945001 Tetraodon_nigroviridis A-AAAAAPSGINP--SVAIGQILPRSTFTFNHTQCILYALGVGMSTK--DPDHLRFLYEG
ENSGALG00000002187 Gallus_gallus TNSRSVVSSAVDT--TSLVGRELTTKVYKYTHLEPILYALGVGMSTK--DPDHLKFLFEG
ENSDARG00000031873 Danio_rerio T-AVATNP-------AQAIGHVLPDMTFTHTHMNCILYALGVGVSSR--DPQQLQFLYEG
ENSCING00000009223 Ciona_intestinalis --NDLGSSHPIKP--KLAKQHKFAPVTTYHDHNKVILYALGVGASTK--QKDHLKFLFEM
ENSANGG00000011810 Anopheles_gambiae -------------------NENSVTETFRYGFKDAILYALGVGASVT--DPTDLKFLYEN
CG3415 Drosophila_melanogaster ---------------------DAIEDAFEFNSKELITYALGIGASVK--NAKDMRFLYEN
ENSAPMG00000004499 Apis_mellifera ---------------QPSESQNSGVLRHTYNYRDIILYALGVGASVQ--IPTDFRYLYEN
EAS01180 Tetrahymena_thermophila --------------------------------------EAAKKAATT--APAAVDSPYKS
M03A8.1 Caenorhabditis_elegans --------------------------------------SASSGASSGGAFPSNIR-----
DDB0201628 Dictyostelium_discoideum ------------------------------------------------------------
NCU08828.2 Neurospora_crassa --GAAENEHLAAI--KKFTGVEGKGTEYTFTERDVCLYNLGIGAKR-----TDIKYIFEG
XP_746577.1 Aspergillus_fumigatus --GEGGNNILANI--EKAKQATTEGTAFDYIDRDIILYNLSVGAKR-----TDLPLVYEN
CAG79573.1 Yarrowia_lipolytica VAGPGG---------PGILNKEGEPFDYTYTYRDLILYNLGLGAKA-----NELKYVFEG
XP_571589.1 Cryptococcus_neoformans --SYEDPDDTEDI--KAAKRQEVDPHEYNFSERDVILYNLGLGAKV-----DELQWVYEN
NP_986606.1 Eremothecium_gossypii ---------------MTATALQSSTGALKYTSRDSIIYNLGLGANT-----TELKYVYEN
CAG61834.1 Candida_glabrata ---------------KAQAAAATAKDVFEYNHKDVILYNIGLGATS-----KELKYTYEN
YKR009C Saccharomyces_cerevisiae ---------------KAHSSKELDDGLFKYTTKDCILYNLGLGCTS-----KELKYTYEN
CAG99661.1 Kluyveromyces_lactis ---------------HKHAADKAKPKTYKYTSRDVILYNLGLGATT-----RELQYTYEN
CAG84660.1 Debaryomyces_hansenii ---------------DSDDEDDVNERTYTYGDREVILYNIGIGANS-----HELKYVYEN
DDB0214811 Dictyostelium_discoideum ---------------KKVINHKIKPIEYNLTRKDVALYAISLGCGK-----KHLKFVYEG
EAS00575 Tetrahymena_thermophila ---------------QKMLAFRTEECVDTFNSRDAIIYSLSLGYSSDPMNESDLKYTFEL
  
721                                                        780
GENSCAN00000095486 Equus_caballus SSDFSCLPTFGVITAQ-KSMLG--EL--AQIPGL-SLDFAKVLHGEQYLELYK-PLPRT-
ENSMODG00000013536 Monodelphis_domestica NSDFSCLPTFGVIPAQ-KCMMDG-GL--SEVPGL-TIDYTKVLHGEQYLELYK-PLPKTG
ENSMMUG00000017685 Macaca_mulatta SSDFSCLPTFGVIIGQ-KSLMGG-GL--AEIPGL-SINFAK-
ENSG00000133835 Homo_sapiens SSDFSCLPTFGVIIGQ-KSMMGG-GL--AEIPGL-SINFAKVLHGEQYLELYK-PLPRAG
ENSPTRG00000017168 Pan_troglodytes SSDFSCLPTFGVIIGQ-KSMMGG-GL--AEIPGL-SINFAKVLHGEQYLELYK-PLPRAG
Hsd17b4 Rattus_norvegicus SADFSCLPTFGVIVAQ-KSLMSG-GL--AEVPGL-SINFAKVLHGEQYLELYK-PLPRSG
ENSMUSG00000024507 Mus_musculus SADFSCLPTFGVIVAQ-KSMMNG-GL--AEVPGL-SFNFAKALHGEQYLELYK-PLPRSG
ENSCAFG00000000158 Canis_familiaris STDFSCLPTFGVIIAQ-KFVIGG-GL--SEIPGF-SVNLAKVLHGEQYLELYK-PLPRAG
ENSBTAG00000006978 Bos_taurus SSDFSCLPTFGVILAQ-KSIMNG-GL--AEIPGL-SINLAKILHGEQYLELHK-PIPRAG
ENSXETG00000017534 Xenopus_tropicalis SEDFSCLPSFGVIVSQ-AAFMSG-GL--ASVPGL-NIDFTRVLHGEQYLEIYK-PLPTSG
NEWSINFRUG00000152986 Takifugu_rubripes HPDFSCLPTFGVIPSQ-AAMMDG-GL--ASIPGL-NIDFTQVLHGEQYLEFYR-PLPTSG
GSTENG00030945001 Tetraodon_nigroviridis HPDFSCLSHFGVIPPQ-AAFME--GL--TSVPGL-TIDLTQMLHGEQYLELYR-PLPTSG
ENSGALG00000002187 Gallus_gallus SEEFCCLPTFGVIPAQ-TSMFD--GV--PSIPGL-DMDLAKMLHGEQYLELYK-PLPTSG
ENSDARG00000031873 Danio_rerio HTHFSCLPTFGVIPAQ-GALL---GL--GSIPGL-DIDFTRLLHGEQYLELYK-PLPTSG
ENSCING00000009223 Ciona_intestinalis NEDFSVLPSFGVIPAF-SSML----I--ADVKGL-EFNMTQILHGEQYLELYK-PIPTEG
ENSANGG00000011810 Anopheles_gambiae NPEFAVLPTFFILPGL-LAVMGS-SLTASAIKHT-TFDLTNILHGEQYIELFE-APATEG
CG3415 Drosophila_melanogaster DADFAAIPTFFVLPGL-LLQMSTDKLLSKALPNS-QVDFSNILHGEQYLEIVD-DLPTSG
ENSAPMG00000004499 Apis_mellifera DSNFAVLPTFYVVYAP-MVALEF-SMYEKFLPHI-ELDPTKILHGEQYIEVYK-QLPTEA
EAS01180 Tetrahymena_thermophila DQIFTMMKVF--------------------------------------------------
M03A8.1 Caenorhabditis_elegans ------------------------------------------------------------
DDB0201628 Dictyostelium_discoideum --------------------------------------------GESVL-----------
NCU08828.2 Neurospora_crassa NEDFEVVPTFGVIPPF-NTEMPF-SF--DDIVP--NFSPMMLLHGEQYLEVRKYPIPTSG
XP_746577.1 Aspergillus_fumigatus NEHFQALPTFGVIPWF-NTATPW-NM--DDIVA--NFSPMMLLHGEQYMEIRKFPIPTEA
CAG79573.1 Yarrowia_lipolytica DDDFQTVPTFGVIPYM-GGLITT-NY--GDFVP--NFNPMMLLHGEQYLEIRQWPIPTNA
XP_571589.1 Cryptococcus_neoformans SDGFSAIPTFGVIPQF-GASHGV-DM--GNFVP--NFNPAKLLHGEQYLKIKA-PIPTSG
NP_986606.1 Eremothecium_gossypii HPAFQVLSTYPIVLAMNAGFV---DF--PSFAD--NFDYNMLLHGEQYMKLNQYPVPTEG
CAG61834.1 Candida_glabrata DSNFQVLPTFAVMPVF-N-SPPL-AM--DTLVD--NFNYAMLLHGEQYFKIGQNPIPVKG
YKR009C Saccharomyces_cerevisiae DPDFQVLPTFAVIPFM-QATATL-AM--DNLVD--NFNYAMLLHGEQYFKLCTPTMPSNG
CAG99661.1 Kluyveromyces_lactis HPQFQVLPTFATIPYMADGSIDI-KF--DELVD--NFNYAMLLHGEQYFKINKFPLPTSG
CAG84660.1 Debaryomyces_hansenii DSDFQVIPTFGHLVTFLSGKSTH-SF--AKLLK--NFNPMYLLHGEHYLKVEKYPIPTEA
DDB0214811 Dictyostelium_discoideum SDNFSALPTLGVIFPG-QMIV---DVISEGIDGI-EFDPMMLLHGEQELEILN-EIPVEG
EAS00575 Tetrahymena_thermophila NDEFKAFPTFACVLPKIDIFKAL-----TSCPGLPNFNPMMLLHGEQRLETYR-PLVPDT
  
781                                                        840
GENSCAN00000095486 Equus_caballus ------------------------VYSY-----SGNELLCYNQFSLFLVGSGGFGGKRTS
ENSMODG00000013536 Monodelphis_domestica QLTNEAIIVDILDKG-SGLVILLDVYSY-----SGKELICFNQFTVFVVGSGGFGGKKTS
ENSMMUG00000017685 Macaca_mulatta -YSY-----SEKELICHNQFSLFLVGSGGFGGKRTS
ENSG00000133835 Homo_sapiens KLKCEAVVADVLDKG-SGVVIIMDVYSY-----SEKELICHNQFSLFLVGSGGFGGKRTS
ENSPTRG00000017168 Pan_troglodytes KLKCEAVVADVLDKG-SGVVIIMDVYSY-----SEKELICHNQFSLFLVGSGGFGGKRTS
Hsd17b4 Rattus_norvegicus ELKCEAVIADILDKG-SGIVIVMDVYSY-----SGKELICYNQFSVFVVGSGGFGGKRTS
ENSMUSG00000024507 Mus_musculus ELKCEAVIADILDKG-SGVVIVMDVYSY-----SGKELICYNQFSVFVVGSGGFGGKRTS
ENSCAFG00000000158 Canis_familiaris NLRCEAVVADVLDKG-SGSVILVDVYSY-----FEEELICYNQFSLFLVGSGGTGGKRTS
ENSBTAG00000006978 Bos_taurus KLRCEAIVADILDKG-SGLVILVDVYTY-----SGEELICYNQFSIFVVGSGGSGGKRTS
ENSXETG00000017534 Xenopus_tropicalis EMTSHATVADIMDKG-SGAIILLDVHTY-----HGVDLVCYNQFSVFVVGAGGFGGKRSS
NEWSINFRUG00000152986 Takifugu_rubripes TLTSEATIADVLDKG-SGAVILLDVNTY-----SGGELICYNQFSVFVVGAGRFGGTRTS
GSTENG00030945001 Tetraodon_nigroviridis TLTSEATIADVLDKG-SGAVVLLDVNTY-----SGEELICYNQFSLFVVGAGGFGGKRTS
ENSGALG00000002187 Gallus_gallus ELRSVSTIADLLDKG-SGAVLLIDVNTY-----CGKDLVCYNQFSLFFVGAGGFGGKRTS
ENSDARG00000031873 Danio_rerio TLTSRATVADVLDKG-SGMLILLDVHTY-----SEQELLCYNQFSVFIVGSGGFGGKRVS
ENSCING00000009223 Ciona_intestinalis KLTSQATIVDVLDKG-SGAAIIMDVVTK----DESGEKVFYNQFVTFVVGAGGFNGKRSS
ENSANGG00000011810 Anopheles_gambiae VLTTTSTVLDVVDKK-SGALVITQSDSY----DEQGTLVARNQSSTFVVGAGNFNGKTKA
CG3415 Drosophila_melanogaster TLLTNGKVFDVMDKG-SGAVVVTNSESF----DESGRLLVRNQSTTFIVGAGKFGGKKDP
ENSAPMG00000004499 Apis_mellifera TVETRYKIVDVVDKG-KGALVVIQHDTF---DTSNEDKLSTGQMIIFVIGAGNFKGKRTS
EAS01180 Tetrahymena_thermophila -----------LERG---------------------------------------------
M03A8.1 Caenorhabditis_elegans ------------------------------------------------------------
DDB0201628 Dictyostelium_discoideum ------------------------------------------------------------
NCU08828.2 Neurospora_crassa RLVSKGKLLEVVDKG-SAAIVKQGITTF---NAETGEELFYNEMTVFLRGCGGFGGQKKP
XP_746577.1 Aspergillus_fumigatus KTLTYPKLIDVVDKG-KAALVVAGYTTK---DAKTGEDLFYNESTVFIRGSGGFGGSPKP
CAG79573.1 Yarrowia_lipolytica TLENKAKVIDVVDKG-KAALLVTATTTT---NKETGEEVFYNESSLFIRGSGGFGGKSTG
XP_571589.1 Cryptococcus_neoformans TLVSHARLLEVLDKG-KAAAVTFIIDTK---DKKTGESIFENQSTVILRGSGGFGGKKNG
NP_986606.1 Eremothecium_gossypii SVKVETAPVASTNKGKKAALIVIGYKVI---DAKTNKQLAYTEGSYFVRGAQVPESKKVL
CAG61834.1 Candida_glabrata ALKTEVKPLQVIDKGGKAAVIVAGYKSV---DAKTNKLVSYNESTFFVRGAHVPPNKKKY
YKR009C Saccharomyces_cerevisiae TLKTLAKPLQVLDKNGKAALVVGGFETY---DIKTKKLIAYNEGSFFIRGAHVPPEKEVR
CAG99661.1 Kluyveromyces_lactis ELRTTGKPLQVLGKSSKAAIIVGGYETV---DAKTNEPVIYNEGTFFVRNAVVPDNKVIN
CAG84660.1 Debaryomyces_hansenii SMLTEFKPLAVTQKG-TNSIVVHGLKTV---DAKTGELLFTNEATYFIRKCEG-ETKVYG
DDB0214811 Dictyostelium_discoideum VFVTESKITNLYDKG-KGALLILQCITS---EKSSGKPIFKNIFSFFIRGIGGFGGDRGP
EAS00575 Tetrahymena_thermophila KYVTQARIADVADKV-KGMLLSFELLSYEVDENNKKHLAFKNIMNVFIRKLGGFGFKGNN
  
841                                                        900
GENSCAN00000095486 Equus_caballus DKMKRCRSFAQEASQAVMIESSEALSKEIDLFWNGVFGSSKVAVAVP-NRPPDAILTDTT
ENSMODG00000013536 Monodelphis_domestica DK-------------------------------------AKVTVPPP-KRPPDAILTDTT
ENSMMUG00000017685 Macaca_mulatta DK-------------------------------------VKVAVAIP-NRPPDAVLTDTT
ENSG00000133835 Homo_sapiens DK-------------------------------------VKVAVAIP-NRPPDAVLTDTT
ENSPTRG00000017168 Pan_troglodytes DK-------------------------------------VKVAVAIP-NRPPDAVLTDTT
Hsd17b4 Rattus_norvegicus EK-------------------------------------LKAAVAVP-SRPPDAVLRDTT
ENSMUSG00000024507 Mus_musculus EK-------------------------------------LKAAVAVP-NRPPDAVLRDAT
ENSCAFG00000000158 Canis_familiaris DK-------------------------------------VKATVAVP-NRPPDAVLTDTT
ENSBTAG00000006978 Bos_taurus DK-------------------------------------AKAAVAIP-NRPPDAVLTDTT
ENSXETG00000017534 Xenopus_tropicalis SK-------------------------------------AKATANPP-SRPPDVVVTDAT
NEWSINFRUG00000152986 Takifugu_rubripes AK-------------------------------------AKAPLPPP-KRAPDAVVTDCT
GSTENG00030945001 Tetraodon_nigroviridis AK-------------------------------------SKASLPAP-KRAPDVVMTDCT
ENSGALG00000002187 Gallus_gallus EK-------------------------------------AKVTVNPP-KRPPDAILSDVT
ENSDARG00000031873 Danio_rerio QK-------------------------------------AVAPAAPP-DRPADAVVVEET
ENSCING00000009223 Ciona_intestinalis EH-------------------------------------LKAVAKHP-NRKPDSFIEQQT
ENSANGG00000011810 Anopheles_gambiae GP------------------------------------EVKPLVPNP-KRSPDASVEVPT
CG3415 Drosophila_melanogaster IA------------------------------------GVVPLQPAP-NRQPDATVQYTT
ENSAPMG00000004499 Apis_mellifera SY-------------------------------------IIPTIESP-NREPDTSVTQQT
EAS01180 Tetrahymena_thermophila ------------------------------------------------------------
M03A8.1 Caenorhabditis_elegans ------------------------------------------------------------
DDB0201628 Dictyostelium_discoideum ------------------------------------------------VRPPKVAVPKAL
NCU08828.2 Neurospora_crassa A----------------------------------DRGASTAANKPP-ARSPDAVVEVQT
XP_746577.1 Aspergillus_fumigatus TA-------------------------------S-RPKGATAAYNPP-KRQPDVVIEEKT
CAG79573.1 Yarrowia_lipolytica T----------------------------------DRGAATAANKPP-ARAPDFVKEIKI
XP_571589.1 Cryptococcus_neoformans KD-------------------------------R---GAATALNVPP-KRKPDAVMEEKT
NP_986606.1 Eremothecium_gossypii TE---------------------------------RPTFSTTSFSSP-DREPDFEAEIDT
CAG61834.1 Candida_glabrata NE-------------------------------P-RAPFAVQSFQAPTDRAPDYEVEVQT
YKR009C Saccharomyces_cerevisiae DG-------------------------------K-RAKFAVQNFEVPHGKVPDFEAEIST
CAG99661.1 Kluyveromyces_lactis KA-------------------------------KERSPFATKAFVTKDLGDPDFEAEIST
CAG84660.1 Debaryomyces_hansenii D----------------------------------RKAFATKQFNAP-NSSPDFTIDVKI
DDB0214811 Dictyostelium_discoideum NE--------------------------------------KPIQIPK-DRAPDAISKQAT
EAS00575 Tetrahymena_thermophila S--------------------------------------TPVLPKKP-TRQPDATHLEKT
  
901                                                        960
GENSCAN00000095486 Equus_caballus SLNQAALYRLS-GDWNPLHIDPNFSSLAGFDKPILHGLCTFGFSARHVLQQFADHDVSRF
ENSMODG00000013536 Monodelphis_domestica SLNQAVLYRLS-GDWNPLHIDPSFASLGGFEKPILHGLCSFGYAARHILQQFGNNDVSRF
ENSMMUG00000017685 Macaca_mulatta SLNQAALYRLS-GDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRILQQFADNDVSRF
ENSG00000133835 Homo_sapiens SLNQAALYRLS-GDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRF
ENSPTRG00000017168 Pan_troglodytes SLNQAALYRLS-GDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRF
Hsd17b4 Rattus_norvegicus SLNQAALYRLS-GDSNPLHIDPSFASIAGFEKPILHGLCTFGFSARHVLQQFADNDVSRF
ENSMUSG00000024507 Mus_musculus SLNQAALYRLS-GDWNPLHIDPDFASVAGFEKPILHGLCTFGFSARHVLQQFADNDVSRF
ENSCAFG00000000158 Canis_familiaris SLNQAALYRLS-GDWNPLHIDPNFAGFAGFDKPILHGLCTFGFSARHVLQKFADNDVSRF
ENSBTAG00000006978 Bos_taurus SLNQAALYRLS-GDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARHVLQQFADNDVSRF
ENSXETG00000017534 Xenopus_tropicalis NADQAALYRLS-GDWNPLHIDPSFAAMGGFEKPILHGLCSFGFSARHVLKHFANNDVTKF
NEWSINFRUG00000152986 Takifugu_rubripes TRDQAALYRLS-GDWNPLHIDPGFAAMGGFKAPILHGLCSFGFAARHVLKQFANNDPSRF
GSTENG00030945001 Tetraodon_nigroviridis TRDQAALYRLS-GDWNPLHIDPSFAAIGGFKAPILHGLCSFGFAARHVLKQFANNEPSRF
ENSGALG00000002187 Gallus_gallus TSDQAALYRLS-GDWNPLHLDPSFAALGGFQKPILHGLCTFGFAARNVLKQFANNDVTRF
ENSDARG00000031873 Danio_rerio SRDQAALYRLS-GDWNPLHIDPNFAAMGGFQSPILHGLCSFGFAARHVLKQFAGNDVSRF
ENSCING00000009223 Ciona_intestinalis SNDQAALYRLS-GDNNPLHIDPSFAAMGGFKQPILHGLCSFGFSTRHVMEKYAGNDPTKI
ENSANGG00000011810 Anopheles_gambiae HQNQAAVYRLS-GDLNPMHIDPSFSAIAGYKVPILHGLCTMGVSVKAVLKQFGGDDPTLF
CG3415 Drosophila_melanogaster SEDQAALYRLS-GDKNPLHIDPQMALLAGFKTPILHGLCTLGFSVRAVLAQFADNNPALF
ENSAPMG00000004499 Apis_mellifera SQDQAALYRLS-GDQNPLHIDSNMSMIAGFKRPILHGLCTLGFSVRHILQTYTGGDPSLF
EAS01180 Tetrahymena_thermophila ------------------------------------------------------------
M03A8.1 Caenorhabditis_elegans ------------------------------------------------------------
DDB0201628 Dictyostelium_discoideum A-----------------------------------------------------------
NCU08828.2 Neurospora_crassa TEEQAAIYRLS-GDYNPLHVDPAFAKVGGFKVPILHGLCSFGIAGKAVYEKYGK-----F
XP_746577.1 Aspergillus_fumigatus SEDQAALYRLN-GDRNPLHIDPEFSKVGGFKTPILHGLCSLGISGKHVFNKFGA-----F
CAG79573.1 Yarrowia_lipolytica QEDQAAIYRLS-GDYNPLHIDPAFAAVGNFDRPILHGLCSFGVSGKALYDQFGP-----F
XP_571589.1 Cryptococcus_neoformans TLDQAAIYRLS-GDYNPLHIDPDFASMGGFPKPILHGLCSMGIAGKHVLKTFGS-----Y
NP_986606.1 Eremothecium_gossypii SVHQAALYRLA-GDYNPLHIDPKVSSIARFPKPILHGLCSLGCTAKALFEKFGQ-----Y
CAG61834.1 Candida_glabrata HKDQAAIYRLS-GDFNPLHIDPALAKQVGFPSPIIHGLCTLGVSSKAVLEKFGP-----Y
YKR009C Saccharomyces_cerevisiae NKDQAALYRLS-GDFNPLHIDPTLAKAVKFPTPILHGLCTLGISAKALFEHYGP-----Y
CAG99661.1 Kluyveromyces_lactis FEDQAALYRLS-GDYNPLHIDPQLAKSVKFPKPILHGLCTLGVSAKELFEKYGP-----F
CAG84660.1 Debaryomyces_hansenii SEHQASLYRLN-GDRNPLHLDPEFAKGANFDKPILHGMCTYGMSAKVLLDKFGP-----F
DDB0214811 Dictyostelium_discoideum SEDQAVIYRLAGGDLNPLHIDPEMSKIGGFEVPILHGLCTYGIASRGVLEHFCDNDPSRL
EAS00575 Tetrahymena_thermophila TPNQAILYRLN-GDYNPLHIDPSMAAMGGFDKPILHGMCFYGLMTKAVVVKFLDNDSSRV
  
961                                                        1020
GENSCAN00000095486 Equus_caballus KAIK------------------------------IQETGDIVISNAYVDLVPTSDM-LAK
ENSMODG00000013536 Monodelphis_domestica RAIKARFAKPVYPGQTLLTEMWKE-GNRIHFQTKVQETGDIVLSNAYVDLVPTSDVLSTK
ENSMMUG00000017685 Macaca_mulatta KAIKARFAKPVYPGQTLQTEMWKE-GNRIHFQTKVQETGDIVISNAYVDLAPTSDT-SAK
ENSG00000133835 Homo_sapiens KAIKARFAKPVYPGQTLQTEMWKE-GNRIHFQTKVQETGDIVISNAYVDLAPTSGT-SAK
ENSPTRG00000017168 Pan_troglodytes KAIKARFAKPVYPGQTLQTEMWKE-GNRIHFQTKVQETGDIVISNAYVDLAPTSDT-SAK
Hsd17b4 Rattus_norvegicus KAIKVRFAKPVYPGQTLQTEMWKE-GNRIHFQTKVQETGDIVISNAYVDLVPTSGV-SAQ
ENSMUSG00000024507 Mus_musculus KAIKVRFAKPVYPGQTLQTEMWKE-GNRIHFQTKVHETGDVVISNAYVDLVPASGV-STQ
ENSCAFG00000000158 Canis_familiaris KAIKVRFAKPVYPGQTLQTEMWKE-GNRIHFQTKIQETGDIVISNAYVDLMPTSDT-SAQ
ENSBTAG00000006978 Bos_taurus KAIKV-------------------------------------------------------
ENSXETG00000017534 Xenopus_tropicalis KAIKVRFAKPVLPGQTLQTEMWKE-GNRIFLQTKVKDTGEIAIAGAYVDLTSTENNLESK
NEWSINFRUG00000152986 Takifugu_rubripes KAIKVRFAKPVMPGQSLQTAMWKE-GSRIHIECKVKETSDVVLSGAYVDLHQAAEA-SPE
GSTENG00030945001 Tetraodon_nigroviridis KAIKVRFVKPVMPGQSLQTAMWKE-GSRIHIECTVKETNDVVLSGAYVDLHQAAEA-SPE
ENSGALG00000002187 Gallus_gallus KAIKVRFAKPVFPGQTLQTEMWKE-GNRIHFQTKVKETGDLAIAGGYVDIVSALDKPSAL
ENSDARG00000031873 Danio_rerio KAMKVRFVKPVYPGQSLQTEMWKE-NSRVHIQCTVKESGAVVLSGAYIDLHPAASV-NTG
ENSCING00000009223 Ciona_intestinalis KAIKVRFAKPVIPGQTLRTEMWKE-GNRIHFQTIVAETGKPSLSGAYIDLTEAI---VDE
ENSANGG00000011810 Anopheles_gambiae RAAKVRFSKPVLPGQTLRVDMWKEPNNRVCFRTVVVETSTEVLSGKW-------------
CG3415 Drosophila_melanogaster KAVKVRFSGPVIPGQTLRVDLWKQ-GTRINFRTVVVETGKEVISGAYVDLKSS-------
ENSAPMG00000004499 Apis_mellifera KAIKTRFAKPVIPGQTLRTDMWQE-GNRIHFQTHTVEENILVLSGGYVDLTNTISIQSKE
EAS01180 Tetrahymena_thermophila ------------------------------------------------------------
M03A8.1 Caenorhabditis_elegans ------------------------------------------------------------
DDB0201628 Dictyostelium_discoideum ----------ATPSGSVVVDGYNA------------------------------------
NCU08828.2 Neurospora_crassa KNIKVRFAGTVNPGQTLVTEMWKE-GNKVVFQTKVKETGKLAISGAAAELA---------
XP_746577.1 Aspergillus_fumigatus KSLKVRFAGVVLPGQTLKTEMWKE-GNTVIFQTTVVETGKPAILGAGAELLEGA------
CAG79573.1 Yarrowia_lipolytica KNAKVRFAGHVFPGETLKVEGWKE-GNKVIFQTKVVERGTTAISNAAIELFPK-------
XP_571589.1 Cryptococcus_neoformans SDIKVRFAGTVIPGETLVTEMWKE-GNKVIFSAKVKERDAPALSNAAVTLIGAEGAV---
NP_986606.1 Eremothecium_gossypii DELKTRFSSFVFPGDKLKVRAWKEDGGIVIFETIDLDRDMPVLTNSAIKLVGS-------
CAG61834.1 Candida_glabrata EELKVRFTNAVFPGDTLKVRAWKQPNNVVIFQTVDLNTKKIVLDNAAVKLVGP-------
YKR009C Saccharomyces_cerevisiae EELKVRFTNVVFPGDTLKVKAWKQ-GSVVVFQTIDTTRNVIVLDNAAVKLSQA-------
CAG99661.1 Kluyveromyces_lactis DELKARFTNVVFPGDRLKVKAWKK-NDVVIFQTTDLNTGKIVLDNSAIKLIG--------
CAG84660.1 Debaryomyces_hansenii DEIKGRFTGIVFPGETLKVLAWKQ-GDIVIFQVHVVERKTIAINNAAIKLINN-------
DDB0214811 Dictyostelium_discoideum KSIKTRFTKHVYPGETIETEMWKINPTTILFQSKTNRDGSYVLSSGVAIIEPIK------
EAS00575 Tetrahymena_thermophila STAQARFTSHVFPGETIEFQLWKD-GDKVFVSGATVERKLECIVGV-VELKP--------
  
1021                                                        1080
GENSCAN00000095486 Equus_caballus ---TPSKGGELQSTLVFEEIGRRLKDIGHQVVKTVNAVFEWHITEGGNTAATW-------
ENSMODG00000013536 Monodelphis_domestica ---VSSKDGTLQSTLVFEEIGRRIKDVGKELVKKVNAVFQWNITKHGQTAAQWIELYKLI
ENSMMUG00000017685 Macaca_mulatta ---TPSEGGKLQSTLVFEEIGRRLKDVGPEVVKKVNAVFEWHITKGGNIGAKW-------
ENSG00000133835 Homo_sapiens ---TPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKW-------
ENSPTRG00000017168 Pan_troglodytes ---TPSEGEKLQSTLVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKW-------
Hsd17b4 Rattus_norvegicus ---TPSEGGALQSALVFGEIGRRLKDVGREVVKKVNAVFEWHITKNGNVAAKWMEL--TI
ENSMUSG00000024507 Mus_musculus ---TPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTVAAKW-------
ENSCAFG00000000158 Canis_familiaris ---TPSEGGELQSTLVFEEIGRRLKDIGHEVAKKVNAVFEWHITKGGNIAAKW-------
ENSBTAG00000006978 Bos_taurus ------------------------------------------------------------
ENSXETG00000017534 Xenopus_tropicalis ---GPVQDGGLQSDLVFDEISRRVKDLGEQLVKKVNAVFQWDITKDGKPASQW-------
NEWSINFRUG00000152986 Takifugu_rubripes ---PPSQGGRLQSDLVFTEIGRRISEVGPELVKKVNAVFGWEITKEGKTAAQW-------
GSTENG00030945001 Tetraodon_nigroviridis ---PPAQGGALQSDLVFAEIGRRIKEAGSELVKKVNAVFSWEITKEGRTAAHW-------
ENSGALG00000002187 Gallus_gallus ---EPT--AGLQSDLVFEEIGRRIKEVGHELVRKVNAVFQWDITKDGKTAVQW-------
ENSDARG00000031873 Danio_rerio ---PPQ--ARLQSDLVFAEIERRIKDSGEELVKNVNAVFGWEITTDGETRSHW-------
ENSCING00000009223 Ciona_intestinalis ---PKAVAGSLLSDALFEAAADRLT---PDVIRKVNASFQWNITKNGKVVKSW---GGLG
ENSANGG00000011810 Anopheles_gambiae ------------------------------------------------------------
CG3415 Drosophila_melanogaster ------------------------------------------------------------
ENSAPMG00000004499 Apis_mellifera NLSSDISNTSLESDAVFFKIAEYVK-TNSDEVKKINGVFLYHILVNGKLKAQWSNYIK--
EAS01180 Tetrahymena_thermophila --------------------------EGTKLVKDLQAVYGFNIVEKKNGPVKRAY-----
M03A8.1 Caenorhabditis_elegans ------------SSALFQEMADGVK-ADPTAVKTLKSIVLYIITDGKNELGKF-------
DDB0201628 Dictyostelium_discoideum -------------SKIFTTIQGNIGAKGAELVKKINGIYLINIKKGTNTQAW--------
NCU08828.2 Neurospora_crassa ------------------------------------------------------------
XP_746577.1 Aspergillus_fumigatus ------------------------------------------------------------
CAG79573.1 Yarrowia_lipolytica ------------------------------------------------------------
XP_571589.1 Cryptococcus_neoformans ------------------------------------------------------------
NP_986606.1 Eremothecium_gossypii ------------------------------------------------------------
CAG61834.1 Candida_glabrata ------------------------------------------------------------
YKR009C Saccharomyces_cerevisiae ------------------------------------------------------------
CAG99661.1 Kluyveromyces_lactis ------------------------------------------------------------
CAG84660.1 Debaryomyces_hansenii ------------------------------------------------------------
DDB0214811 Dictyostelium_discoideum ------------------------------------------------------------
EAS00575 Tetrahymena_thermophila ------------------------------------------------------------
  
1081                                                        1140
GENSCAN00000095486 Equus_caballus -----------TIDLKNGSGEVYQGPARG--SADTTLTLSDEHFMEVVQGKLDPQKAFFS
ENSMODG00000013536 Monodelphis_domestica PFFSFSFLPFPAIDLKNGSGELYQGPARG--SADTSFTLSDENFMEVVLGKLNPQKAFFS
ENSMMUG00000017685 Macaca_mulatta -----------TIDLKSGSGKVYQGPAKG--AADTTIILSDEDFMEVVLGKLDPQKAFFS
ENSG00000133835 Homo_sapiens -----------TIDLKSGSGKVYQGPAKG--AADTTIILSDEDFMEVVLGKLDPQKAFFS
ENSPTRG00000017168 Pan_troglodytes -----------TIDLKSGSGKVYQGPAKG--AADTTIILSDEDFMEVVLGKLDPQKAFFS
Hsd17b4 Rattus_norvegicus SFSVSSLLPANAIDLKNGSGEVYQGPAKG--SADTTITISDEDFMEVVLGKLNPQNAFFS
ENSMUSG00000024507 Mus_musculus -----------TIDLKSGSGEVYQGPAKG--SADVTIIISDEDFMEVVFGKLDPQKAFFS
ENSCAFG00000000158 Canis_familiaris -----------TIDLKSGFGKVYQGPAKG--PADATFTLSDEDFMDVVLGKLDPQKAFFS
ENSBTAG00000006978 Bos_taurus ------------------------------------------------------------
ENSXETG00000017534 Xenopus_tropicalis -----------TIDLKSGSGEVYRGKARG--RADTSFTLSDEDFMELVLGNLNPQKAFFA
NEWSINFRUG00000152986 Takifugu_rubripes -----------TIDLKNGAGSLQKGPYGG--KVDVTFTVADEDFMEVVQGKLNPQKAFFS
GSTENG00030945001 Tetraodon_nigroviridis -----------SFLLGQAEGQREH-------HAEPEAGGHPEGLRQTVTSPAG-QSDGCR
ENSGALG00000002187 Gallus_gallus -----------TIDLKNGSGSVYQGPARS--SADTTFTLSDQDFMDVVQKKTNPQKAFFS
ENSDARG00000031873 Danio_rerio -----------TVDLKTGRGSVQRAAAK----ADVTFTVSDQDFMEVVMGKLNPQKAFFA
ENSCING00000009223 Ciona_intestinalis FFLSVAYLKLSYMNLTKDAGYIKQGEA-S--KPGCTVTVSDDDVMAIFSGSLNPQQAFFK
ENSANGG00000011810 Anopheles_gambiae ------------------------------------------------------------
CG3415 Drosophila_melanogaster ------------------------------------------------------------
ENSAPMG00000004499 Apis_mellifera -----------ALDLK--KSEVYRGEPKS--KPDATLTLEDADMIQMALGKLNPQVAFVR
EAS01180 Tetrahymena_thermophila -----------TIDLKNGQGAVVFQEAKT---ADATFTMIDGDFEQVCLGKLNPNNAFMT
M03A8.1 Caenorhabditis_elegans -----------TLDFKSASPSVYLGDVKNGEKANATVTVADSDFVDIAAGKLNAQKAFMS
DDB0201628 Dictyostelium_discoideum -----------ALDLKNGSGSIVVGAGST--KPNVTITVSDEDFVDIMTGKLNAQSAFTK
NCU08828.2 Neurospora_crassa ------------------------------------------------------------
XP_746577.1 Aspergillus_fumigatus ------------------------------------------------------------
CAG79573.1 Yarrowia_lipolytica ------------------------------------------------------------
XP_571589.1 Cryptococcus_neoformans ------------------------------------------------------------
NP_986606.1 Eremothecium_gossypii ------------------------------------------------------------
CAG61834.1 Candida_glabrata ------------------------------------------------------------
YKR009C Saccharomyces_cerevisiae ------------------------------------------------------------
CAG99661.1 Kluyveromyces_lactis ------------------------------------------------------------
CAG84660.1 Debaryomyces_hansenii ------------------------------------------------------------
DDB0214811 Dictyostelium_discoideum ------------------------------------------------------------
EAS00575 Tetrahymena_thermophila ------------------------------------------------------------
  
1141                                                        1200
GENSCAN00000095486 Equus_caballus GKLKAKGNIMVSQKLQKIL------KD-----YAKL
ENSMODG00000013536 Monodelphis_domestica GKLQVKGNIMLSQKLEMIL------KD-----HAKL
ENSMMUG00000017685 Macaca_mulatta GRLKARGNIMLSQKLQMIL------KD-----YAKL
ENSG00000133835 Homo_sapiens GRLKARGNIMLSQKLQMIL------KD-----YAKL
ENSPTRG00000017168 Pan_troglodytes GRLKARGNIMLSQKLQMIL------KD-----YAKL
Hsd17b4 Rattus_norvegicus GRLKARGNIMLSQKLQMIL------KD-----YAKL
ENSMUSG00000024507 Mus_musculus GRLKARGNIMLSQKLQMIL------KD-----YAKL
ENSCAFG00000000158 Canis_familiaris GRLKARGNIMLSQKLQMIL------KD-----YAKL
ENSBTAG00000006978 Bos_taurus ------------------------------------
ENSXETG00000017534 Xenopus_tropicalis GKLKVKGNIMLSQKLEMIL------KD-----YAKL
NEWSINFRUG00000152986 Takifugu_rubripes GKLKVRGNIMLSQKLEVIL------KD-----YAKL
GSTENG00030945001 Tetraodon_nigroviridis DEAAVDPAALLSCN----------------------
ENSGALG00000002187 Gallus_gallus GKLKVKGNIMLSQKLEMIL------KD-----YAKL
ENSDARG00000031873 Danio_rerio GKLKVKGNIMLSQKLEAVL------KD-----QARL
ENSCING00000009223 Ciona_intestinalis GQMKVSGNIMLAQKLEVIF------KS-----QAKL
ENSANGG00000011810 Anopheles_gambiae ---------------------------------NLA
CG3415 Drosophila_melanogaster --------------------------------QAKL
ENSAPMG00000004499 Apis_mellifera QKLKITGNIMLTQKLKTLIEAS----------KSKL
EAS01180 Tetrahymena_thermophila GKMKIKGHMGKATKFTPALFPPPTPENIAKYTPAKL
M03A8.1 Caenorhabditis_elegans GKLKVKGNVMLLQKLQTVLEKAK---------KSKL
DDB0201628 Dictyostelium_discoideum GKLKISGNMGLATKLGALMQ------------GSKL
NCU08828.2 Neurospora_crassa ------------------------------------
XP_746577.1 Aspergillus_fumigatus --------------------------------KAKL
CAG79573.1 Yarrowia_lipolytica --------------------------------DAKL
XP_571589.1 Cryptococcus_neoformans --------------------------------KAKL
NP_986606.1 Eremothecium_gossypii --------------------------------QSKL
CAG61834.1 Candida_glabrata --------------------------------VAKL
YKR009C Saccharomyces_cerevisiae --------------------------------KSKL
CAG99661.1 Kluyveromyces_lactis --------------------------------KSKL
CAG84660.1 Debaryomyces_hansenii --------------------------------KAKI
DDB0214811 Dictyostelium_discoideum --------------------------------KGSL
EAS00575 Tetrahymena_thermophila --------------------------------AAKL
  
1201                                                        1260