Gene : PKT2

Symbol :	PKT2
Name/description :	PKT2 (PEROXISOMAL 3-KETO-ACYL-COA THIOLASE 2); acetyl-CoA C-acyltransferase/ catalytic
Synonyms :	3-KETO-ACYL-COA THIOLASE, 3-KETO-ACYL-COENZYME A THIOLASE 5, K24G6.22, K24G6_22, KAT5, PEROXISOMAL 3-KETO-ACYL-COA THIOLASE 2, PEROXISOMAL-3-KETO-ACYL-COA THIOLASE 1, PKT1, PKT2
Organism :	Arabidopsis thaliana
Peroxisomal Localization :	GO: peroxisome Sigrun Reumann, et al.2007. Plant Cell GFP: No experiment found Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	ACAA1
Protein consensus sequence :	MAAFGDDIVIVAAYRTAICKARRGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDSVPVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTDHIPGGGFHGSNPRAQDFPKARDCLLPMGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKIVDPETKAEKAIVVSVDDGVRPNSNMADLAKLKTVFKQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKDCRFGVISMCIGTGMGAAAVFERGDSVDNLSNARVANGDSH
Functional category(ies) :	Fatty acid oxidation Fatty acid synthesis/PUFAS synthesis Long-chain dicarboxylic acids oxidation Straight chain fatty acids beta-oxidation Straight chain fatty acids oxidation Unsaturated fatty acid beta-oxidation
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Blastp PsiBlast Alignment Phylogenetic tree [help] Enzyme reaction data
Gene Info:	Gene Summary (NCBI) Chromosomal Localization (NCBI) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	José Castillo, et al.2008. Plant Cell Environ. Peroxisome proliferation, wound-activated responses and expression of peroxisome-associated genes are cross-regulated but uncoupled in Arabidopsis thaliana. Ramasubramanian Sundaramoorthy, et al.2006. J. Mol. Biol. The crystal structure of a plant 3-ketoacyl-CoA thiolase reveals the potential for redox control of peroxisomal fatty acid beta-oxidation. Kathryn Lange, et al.2004. FEBS Lett. An Arabidopsis mutant disrupted in valine catabolism is also compromised in peroxisomal fatty acid beta-oxidation. V Germain, et al.2001. Plant J. Requirement for 3-ketoacyl-CoA thiolase-2 in peroxisome development, fatty acid beta-oxidation and breakdown of triacylglycerol in lipid bodies of Arabidopsis seedlings. H Hayashi, et al.1999. J. Biol. Chem. A novel acyl-CoA oxidase that can oxidize short-chain acyl-CoA in plant peroxisomes.