Gene : LmjF34.1090

Symbol :	LmjF34.1090
Name/description :	acyltransferase
Synonyms :
Organism :	Leishmania major
Peroxisomal Localization :	GO: No Peroxisomal annotation GFP: No experiment found Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	GNPAT
Protein consensus sequence :	PTS1=0.047; start position=1425; end position=1436; MSFPPPRLALPEECKQVVLVAPIDGFTAACACAIATSPLVPLNCRVLVDGIAVKSSSPSSGNDSPHMACSSAESAATARDFMNTVQRVEAKLRASRATRRDVSVTHITQFYYGGVSPKAEEIGPMLHRIHLLGSGALGETNFTASSTDVTAGSGGSSGVPRVADSVFVLVLSAQSLSPDTESGLKAYDILLRRLWSAAGPSQAAETASQQTRVRGSLVILADDVYRTAACAMLSSIAKEVATAVDWVVLLAYAYAMDPPALEFGATEVAVQAASGISLGGTLPVLCAANALGVLRHFPVSRGEPATITPVDVALNAALLGYVWLCHGELPECVECAAEMQYCGLSPAPSHAAAAAETATAMPTQPAQCVTRHRMGSFAVAESRKPGEVSLVWGMVGEYLMSYYGRFADQISAAFPVAGVLTQAPILQFPFSVADWVNFGPEPRAAAYALEGWRAYQQRQRLMEEKVGNAEAAQALKAYVAQMDSVVRYIERTARAAAARDKISAAFAASRRRTASSSFSVPPYRLDDFNVALYHSLLRRLTSHHTLMPYHQCVALVEVDWEAYVSVIARAVLEHLARCVLRSSSGLQHVRSRFHALPVADSANIGSVVRSPPVVSAPDELAPASAAVPSSTKPEAAASAAEAPFAFPEPRRYFTNDFVYRGAERIPPFPSLLHKYFDCFVFLHRVGMTANGWRGDMTPGMTPQVLTSIIAQPNIQRLMTALAAKDGASKKDVEARAKRLLLECGDALNHVHCRTLGLMIRTIFHSIYGRVDVNNGSYERLHRYFAMPRVAVVFAPLHRSYIDFLILSEVLALMRLPLPHIVAGENFLSMGVLATLMRGSGALFMRRSFRDDPLYAALLKEYVRHLVRARRPLEFFIEGARSRTGKTMAPKLGLLKFVCDTFYEPGQQELDDVLIVPVSLSYDEVLEATTHAKELLGVPKPKENPTNMLKARSLLERMHGNIHIHVGEPVSLRSLKQHPRQCPLPLQPKDEQLRDPAAPAAATTSVCKTLDTTPSIAKGSSITPIPLLGTVAWHLVYKLQRNTVITPASMVAAVVECLGPYYCTATTMLKEGIDTTAAAPTAAAAMPLEKVHQGVEWLRGRLRERGAQLSAEASKLNPAGVVTLALTNLYRYIHITDEMSGVTYHPDNVVTRLAVNISTNQLIHVCMNEALVAVVAQAFGFVTTPHRPPSGADGAMLCGVRSVKADVLSNQTQLLQRLLSAEFPNYAEAAPVSFASWLECTVSQLQQCVEEHTVSSQLSGADTHGGTIVHLPVTQYYYFLLQLICPHVEALYTVLAAASALLAAYPGKPFGAAEVVTATQRACYILYAERKLRYIVAANKETLQHYYESLIALSLLQIKRVPITTTPGQSKVNGGVVAYTVGLLGQEAALARLEVLSTQIKALWWHPSAAEGVTIDKAAIQERVLAVYRELTQPSKM
Functional category(ies) :	Etherlipid and plasmalogens synthesis Lipid metabolism
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Alignment Phylogenetic tree [help] Enzyme reaction data
Gene Info:	Gene Summary (NCBI) Chromosomal Localization (NCBI) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	Rachel Zufferey, et al.2006. J. Biol. Chem. Leishmania major expresses a single dihydroxyacetone phosphate acyltransferase localized in the glycosome, important for rapid growth and survival at high cell density and essential for virulence. Bikramjit Raychaudhury, et al.2003. Med. Sci. Monit. Peroxisomal function is altered during leishmania infection. Hart Hart, et al.1984. Mol. Biochem. Parasitol. The occurrence of glycosomes (microbodies) in the promastigote stage of four major Leishmania species.