Gene : CAT

Symbol :	CAT
Name/description :	catalase
Synonyms :	MGC138422, MGC138424
Organism :	Homo sapiens
Peroxisomal Localization :	GO: peroxisome Fumie Hashimoto, et al.2008. Biol. Pharm. Bull. GFP: No experiment found Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	CAT
Protein consensus sequence :	MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPDMVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPDTHRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALEHSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVKNFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
Functional category(ies) :	Antioxidant Catalase
Disease(s) :	Acatalasemia
Comparative genomics:	PTS prediction Blastp PsiBlast Alignment Phylogenetic tree [help] PhylomeDB Enzyme reaction data
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL SNPs (NCBI) Intron/Exon (Ace View: NCBI) Gene Expression (UCSC) Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	Janet Ebberink, et al.2009. Hum. Mutat. Genotype-phenotype correlation in PEX5-deficient peroxisome biogenesis defective cell lines. Kerry-Ann Koepke, et al.2007. Traffic Restoration of peroxisomal catalase import in a model of human cellular aging. Terlecky Terlecky, et al.2006. Biochim. Biophys. Acta Peroxisomes and aging. Hua Wood, et al.2006. Traffic Hypocatalasemic fibroblasts accumulate hydrogen peroxide and display age-associated pathologies. Nobuo Makino, et al.2004. Biochim. Biophys. Acta A metabolic model describing the H2O2 elimination by mammalian cells including H2O2 permeation through cytoplasmic and peroxisomal membranes: comparison with experimental data.