Gene : PIPOX

Symbol :	PIPOX
Name/description :	pipecolic acid oxidase
Synonyms :	LPIPOX
Organism :	Homo sapiens
Peroxisomal Localization :	GO: peroxisome G Dodt, et al.2000. Biochem. J. GFP: No experiment found Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	PIPOX
Protein consensus sequence :	PEX19=0.1; start position=240; end position=249; PTS1=0.027; start position=379; end position=390; MAAQKDLWDAIVIGAGIQGCFTAYHLAKHRKRILLLEQFFLPHSRGSSHGQSRIIRKAYLEDFYTRMMHECYQIWAQLEHEAGTQLHRQTGLLLLGMKENQELKTIQANLSRQRVEHQCLSSEELKQRFPNIRLPRGEVGLLDNSGGVIYAYKALRALQDAIRQLGGIVRDGEKVVEINPGLLVTVKTTSRSYQAKSLVITAGPWTNQLLRPLGIEMPLQTLRINVCYWREMVPGSYGVSQAFPCFLWLGLCPHHIYGLPTGEYPGLMKVSYHHGNHADPEERDCPTARTDIGDVQILSSFVRDHLPDLKPEPAVIESCMYTNTPDEQFILDRHPKYDNIVIGAGFSGHGFKLAPVVGKILYELSMKLTPSYDLAPFRISRFPSLGKAHL
Functional category(ies) :	L-Lysine metabolism Protein/amino acid metabolism
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Blastp PsiBlast Alignment Phylogenetic tree [help] PhylomeDB Enzyme reaction data
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL SNPs (NCBI) Intron/Exon (Ace View: NCBI) Gene Expression (UCSC) Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	G Dodt, et al.2000. Cell Biochem. Biophys. The human L-pipecolic acid oxidase is similar to bacterial monomeric sarcosine oxidases rather than D-amino acid oxidases. G Dodt, et al.2000. Biochem. J. L-Pipecolic acid oxidase, a human enzyme essential for the degradation of L-pipecolic acid, is most similar to the monomeric sarcosine oxidases. Rao Rao, et al.1992. Biochim. Biophys. Acta Assay for L-pipecolate oxidase activity in human liver: detection of enzyme deficiency in hyperpipecolic acidaemia. Rao Rao, et al.1990. Biochim. Biophys. Acta L-pipecolic acid metabolism in human liver: detection of L-pipecolate oxidase and identification of its reaction product. H Wanders, et al.1988. Biochem. Biophys. Res. Commun. Identification of L-pipecolate oxidase in human liver and its deficiency in the Zellweger syndrome.