Gene : Gnpat

Symbol :	Gnpat
Name/description :	glyceronephosphate O-acyltransferase
Synonyms :	DHAPAT, AU019525, D1Ertd819e
Organism :	Mus musculus
Peroxisomal Localization :	GO: peroxisomal matrix R Ofman, et al.1999. Biochim. Biophys. Acta GFP: No experiment found Mass Spectrometry: Sebastian Wiese, et al.2007. Mol. Cell PROTEOMICS PeroxisomeDB annotation
Protein family :	GNPAT
Protein consensus sequence :	PTS1=0.00057; start position=667; end position=678; MDVPSSSSSRFSVGSASPSSVLLYAKDLKKWDEFEDLLEERRHISDFKFAMKCYTPPLYRGITPCKPGDIKSIVLSSEEINYVIKQLSRESLTGVDVLREEASEILEEMSHKLRIGAIRFFAFVLSKIFKQIFSKVCVNEEGIQKLQRAVQEHPVVLLPSHRSYIDFLMLSFILYSYDLPVPVIAAGMDFLGMRVVSELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRCGYAPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEESLYAYEILGVPKPKESTTGLLKARRILSENFGSIHVYFGDPVSLRSLAAGRLNRNTYNLVPRCIPQKQPEDVQAFVTEVAYKMQLLQIENLALSPWLLVVTILLQNQLSMDFDALVEKTLWLKGVTQVFGGFLLWPDNKLPEEVVQSSILLHSNLASLVKDQVVLKMNSGSSQVVNGLVPEHIALLMCSAYRNQLLNIFARPSLVALALHMTPGLRKEDVFSCFSFLRNVFSDEFIFLPGNTLRDFEEGCYLLCKAEAMQMAGKDIILTDKGTAVLQFLTSLFKPFVESYQLLCRYLLHEEDYFGEKEYLVAARKFTRQLLDQGSSQCYDALSSELQKNALAAFVRLGVVEKKKVDSKYVYYVNGPATSKLEEMLGCKKPIGKPATAKL
Functional category(ies) :	Etherlipid and plasmalogens synthesis Lipid metabolism
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Alignment Phylogenetic tree [help] Enzyme reaction data
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	C Thai, et al.2001. Hum. Mol. Genet. Impaired membrane traffic in defective ether lipid biosynthesis. N Hajra, et al.2000. J. Biol. Chem. Induction of the peroxisomal glycerolipid-synthesizing enzymes during differentiation of 3T3-L1 adipocytes. Role in triacylglycerol synthesis. C Thai, et al.1999. FEBS Lett. Synthesis of plasmalogens in eye lens epithelial cells. S Zoeller, et al.1992. J. Biol. Chem. Mutants in a macrophage-like cell line are defective in plasmalogen biosynthesis, but contain functional peroxisomes. Stevens Stevens, et al.1990. J. Biol. Chem. Class F Thy-1-negative murine lymphoma cells are deficient in ether lipid biosynthesis.