Symbol : |
Uox |
Name/description : |
urate oxidase |
Synonyms : |
Uri, Uri2, UOX-2 |
Organism : |
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Peroxisomal Localization : |
- GO: peroxisomal matrix
- GFP: No experiment found
- Mass Spectrometry:
- PeroxisomeDB annotation
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Protein family : |
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Protein consensus sequence : |
PTS1=0.0048; start position=292; end position=303;
MAHYHDDYGKNDEVEFVRTGYGKDMVKVLHIQRDGKYHSIKEVATSVQLTLRSKKDYLHGDNSDIIPTDTIKNTVHVLAKFKGIKSIETFAMNICEHFLSSFSHVTRAHVYVEEVPWKRFEKNGVKHVHAFIHTPTGTHFCDVEQVRNGPPIIHSGIKDLKVLKTTQSGFEGFIKDQFTTLPEVKDRCFATQVYCKWRYQNRDVDFEATWGAVRDIVLKKFAGPYDRGEYSPSVQKTLYDIQVLTLSQLPEIEDMEISLPNIHYFNIDMSKMGLINKEEVLLPLDNPYGKITGTVRRKLPSRL |
Functional category(ies) : |
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Disease(s) : |
No diseases found
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Comparative genomics: |
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Gene Info: |
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Pubmed: |
- N Usuda, et al.1994. J. Cell. Sci. Uric acid degrading enzymes, urate oxidase and allantoinase, are associated with different subcellular organelles in frog liver and kidney.
- K Alvares, et al.1992. Proc. Natl. Acad. Sci. U.S.A. Rat urate oxidase produced by recombinant baculovirus expression: formation of peroxisome crystalloid core-like structures.
- D Hardeman, et al.1990. Biochim. Biophys. Acta Studies on peroxisomal membranes.
- A Aarsland, et al.1990. Biochim. Biophys. Acta The hypolipidemic peroxisome-proliferating drug, bis(carboxymethylthio)-1.10 decane, a dicarboxylic metabolite of tiadenol, is activated to an acylcoenzyme A thioester.
- K Motojima, et al.1988. J. Biol. Chem. Cloning and sequence analysis of cDNA for rat liver uricase.
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