Gene : Hacl1

Symbol :	Hacl1
Name/description :	2-hydroxyacyl-CoA lyase 1
Synonyms :	Hpcl2, Phyh2
Organism :	Rattus norvegicus
Peroxisomal Localization :	GO: No Peroxisomal annotation GFP: No experiment found Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	HPCL2
Protein consensus sequence :	MSESNSAEGSDRSEEQVSGAKVIAQALKTQDVEYMFGVVGIPVTEIALAAQELGIKYIGMRNEQAACYAASAVGYLTGRPGVCLVVSGPGLIHALGGMANANMNCWPLIVIGGSSERNQEAMGAFQEFPQVEACRLYSKFSARPSSIQHIPFVIEKAVRSSIYGRPGACYIDVPADLVTLQESTTSIKYKECCMPPPLSLAETSAVRAAASVLRSAKQPLLIIGKGAAYSHAEDSIRKLVELCNLPFLPTPMGKGVVPDNHPNCVGAARSRALQFADVIVLFGARLNWILHFGLPPRYQADVKFIQIDICAEELGNNVRPSVTLLGDVNAVSKQLLEQFVKNPWQYPTDSKWWETLREKRKNNEAVSKELASKKSLPMNYYTVFYHVQEQLPRNCFIVSEGANTMDIGRTVLQNYLPRHRLDAGSFGTMGVGLGFAIAAAVVAKERSPGQRVICVEGDSAFGFSGMEVETICRYNLPIIILVVNNNGIYQGFDADTWGKILNFQGTATTIPPMCLLPNSHYEQVMTAFGGKGYFVQTPEELQDSLRQALKDTSKPCLINIMIEPQSTRKAQDFHWLTRSNI
Functional category(ies) :	Alpha-oxidation Branched chain fatty acid oxidation
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Alignment Phylogenetic tree [help]
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	R Jansen, et al.2001. Biochem. Biophys. Res. Commun. Identification of pristanal dehydrogenase activity in peroxisomes: conclusive evidence that the complete phytanic acid alpha-oxidation pathway is localized in peroxisomes. S Jansen, et al.1999. Biochim. Biophys. Acta Phytanic acid alpha-oxidation: identification of 2-hydroxyphytanoyl-CoA lyase in rat liver and its localisation in peroxisomes.