Gene : Pmvk

Symbol :	Pmvk
Name/description :	phosphomevalonate kinase
Synonyms :	MGC105660
Organism :	Rattus norvegicus
Peroxisomal Localization :	GO: No Peroxisomal annotation GFP: No experiment found Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	PMVK
Protein consensus sequence :	MAPLGASPRLVLLFSGKRKSGKDFVTERLQSRLGGNICAVLRLSGPLKEQYAREHGLDFQKLLDASTYKETYRRDMICWGEEKRQADPGFFCRKIVEGVSQPIWLVSDTRRMSDIQWFQEAYGALTQTVRVVASEQSRQQRGWVFTRGVDDAESECGLDSFGDFDWVIENHGDEQCLEDQLENLLEFIHAKLQR
Functional category(ies) :	Isoprenoid metabolism Metabolism
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Alignment Phylogenetic tree [help] Enzyme reaction data
Gene Info:	Gene Summary (NCBI) Chromosomal Localization (NCBI) ENSEMBL Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	G Gupta, et al.1999. J. Lipid Res. Differential binding of proteins to peroxisomes in rat hepatoma cells: unique association of enzymes involved in isoprenoid metabolism. N Aboushadi, et al.1999. J. Histochem. Cytochem. Role of peroxisomes in isoprenoid biosynthesis. Wanders Wanders, et al.1998. Biochem. Biophys. Res. Commun. Differential deficiency of mevalonate kinase and phosphomevalonate kinase in patients with distinct defects in peroxisome biogenesis: evidence for a major role of peroxisomes in cholesterol biosynthesis. J Krisans, et al.1994. J. Biol. Chem. Farnesyl-diphosphate synthase is localized in peroxisomes.