Gene : PEX3

Symbol :	PEX3
Name/description :	Peroxisomal membrane protein (PMP) required required for the proper localization and stability of PMPs; interacts with Pex19p Pex3p
Synonyms :	PAS3
Organism :	Saccharomyces cerevisiae
Peroxisomal Localization :	GO: peroxisomal membrane J Höhfeld, et al.1991. J. Cell Biol. W Hettema, et al.2000. EMBO J. Motley Motley, et al.2007. J. Cell Biol. Weidong Tian, et al.2008. Genome Biol. GFP: Klaus Natter, et al.2005. Mol. Cell PROTEOMICS Won-Ki Huh, et al.2003. Nature Marcello Yi, et al.2002. Electrophoresis Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	PEX3
Protein consensus sequence :	MAPNQRSRSLLQRHRGKVLISLTGIAALFTTGSVVVFFVKRWLYKQQLRITEQHFIKEQIKRRFEQTQEDSLYTIYELLPVWRMVLNENDLNLDSIVTQLKDQKNQLTRAKSSESRESSPLKSKAELWNELELKSLIKLVTVTYTVSSLILLTRLQLNILTRNEYLDSAIKLTMQQENCNKLQNRFYNWVTSWWSDPEDKADDAMVMAAKKSKKEGQEVYINEQAFLSLSWWILNKGWLSYNEIITNQIEIEFDGIHPRDTLTLEEFSSRLTNIFRNTNSQIFQQNNNNLTSILLPKDSSGQEFLLSQTLDADALTSFHSNTLVFNQLVNELTQCIESTATSIVLESLINESFHFIMNKVGIKTIAKKKPGQEDQQQYQMAVFAMSMKDCCQEMLQTTAGSSHSGSVNEYLATLDSVQPLDDLSASVYSNFGVSSSFSFKP
Functional category(ies) :	Peroxisome biogenesis (peroxins) Peroxisome membrane assembly
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Blastp PsiBlast Alignment Phylogenetic tree [help] PhylomeDB
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	Yukio Fujiki, et al.2006. Biochim. Biophys. Acta Import of peroxisomal membrane proteins: the interplay of Pex3p- and Pex19p-mediated interactions. Naganand Rayapuram, et al.2006. Biochim. Biophys. Acta The importomer--a peroxisomal membrane complex involved in protein translocation into the peroxisome matrix. Astrid Kragt, et al.2005. J. Biol. Chem. Endoplasmic reticulum-directed Pex3p routes to peroxisomes and restores peroxisome formation in a Saccharomyces cerevisiae pex3Delta strain. Andrei Tam, et al.2005. J. Biol. Chem. Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae. Dominic Hoepfner, et al.2005. Cell Contribution of the endoplasmic reticulum to peroxisome formation.