Gene : PEX28

Symbol :	PEX28
Name/description :	Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and distribution; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p
Synonyms :
Organism :	Saccharomyces cerevisiae
Peroxisomal Localization :	GO: peroxisomal membrane Vizeacoumar Vizeacoumar, et al.2003. J. Cell Biol. GFP: No experiment found Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	PEX24
Protein consensus sequence :	PEX19=0.025; start position=391; end position=400; MSETSSSRRSASKDAVKSYFAGKYNKVLDSILEAEAAISKSPTVAEDLSGSSSSGNSEMSHPSLTASSATSQGISKKELLQQIAGSLFSTSIERLKTAHSSEVSSTPEYSVNDSYGEQECRECDGVFKCSAHFEGAPEYYDDETESGPALEPMTSNSEKDPFIDVFLDKLISRLVPEKLPEREHFSSKTTIEHDLDTGRVPVFSATTLGSNFKKLSKKMGSIFELQDSIVRLLTWRNPTGTVTSLILFTLICFNPMYLVILPIFRFVYGIVVPGYVRKHPLQRSIYPLKRNHGSSLLYDVCYEGKNEYSYGQQFFSKSFMDTLESRNQEIDEISELDKRTENTGELKQGMKVLINLRDMQNMTSGTLHVIEAINSFLRKSSSFQNEECSTKRFFTGFLLIVFLKILSPFVNWSYVCSIFAWCLLIYMHPRAHPKIISFFKTGTMGKEYKNLKKREHQALNMIFDEQPETKFIEIFEIYKKALLPNDWKFFRYSNRIFDPQDPYRRAQQFPPGVDSLADVIPPTGWSFDPNFEWKIDNDVDRWVVERGLNLPITGEFLFDPMFKRRRLIHRVIKNATPVA
Functional category(ies) :	Peroxisome biogenesis (peroxins) Peroxisome division-proliferation Peroxisome matrix protein import Peroxisome membrane assembly
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Blastp PsiBlast Alignment Phylogenetic tree [help] PhylomeDB
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL ENSEMBL Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	David Vizeacoumar, et al.2004. Mol. Biol. Cell Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae. Vizeacoumar Vizeacoumar, et al.2003. J. Cell Biol. YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae. Tam Tam, et al.2002. Mol. Biol. Cell Yarrowia lipolytica cells mutant for the PEX24 gene encoding a peroxisomal membrane peroxin mislocalize peroxisomal proteins and accumulate membrane structures containing both peroxisomal matrix and membrane proteins.