Gene : PEX13

Symbol :	PEX13
Name/description :	Integral peroxisomal membrane required for the translocation of peroxisomal matrix proteins, interacts with the PTS1 signal recognition factor Pex5p and the PTS2 signal recognition factor Pex7p, forms a complex with Pex14p and Pex17p
Synonyms :	PAS20
Organism :	Saccharomyces cerevisiae
Peroxisomal Localization :	GO: peroxisomal membrane R Erdmann, et al.1996. J. Cell Biol. W Girzalsky, et al.1999. J. Cell Biol. Annette Schell-Steven, et al.2005. Mol. Cell. Biol. GFP: Klaus Natter, et al.2005. Mol. Cell PROTEOMICS Won-Ki Huh, et al.2003. Nature Marcello Yi, et al.2002. Electrophoresis Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	PEX13
Protein consensus sequence :	PEX19=0.024; start position=204; end position=213; MSSTAVPRPKPWETSASLEEPQRNAQSLSAMMTSNQQDSRPTEESNNSNSASESAPEVLPRPAALNSSGTYGESNTIPGIYGNSNYGIPYDNNPYSMNSIYGNSIGRYGYGGSYYGNNYGSFYGGGYGAGAGYGMNNGSGLGESTKATFQLIESLIGAVTGFAQMLESTYMATHNSFFTMISVAEQFGNLKEMLGSFFGIFAIMKFLKKILYRATKGRLGIPPKNFAESEGSKNKLIEDFQKFNDSGTINSNEKATRRKISWKPLLFFLMAVFGFPYLLNKFITKLQTSGTIRASQGNGSEPIDPSKLEFARALYDFVPENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIEIIKRRKKIEHVDDETRTH
Functional category(ies) :	Peroxisome biogenesis (peroxins) Peroxisome docking
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Blastp PsiBlast Alignment Phylogenetic tree [help] PhylomeDB
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	Daniela Kerssen, et al.2006. J. Biol. Chem. Membrane association of the cycling peroxisome import receptor Pex5p. Wolfgang Girzalsky, et al.2006. J. Biol. Chem. Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery. Birgit Agne, et al.2003. Mol. Cell Pex8p: an intraperoxisomal organizer of the peroxisomal import machinery. Xinji Pires, et al.2003. J. Mol. Biol. The ScPex13p SH3 domain exposes two distinct binding sites for Pex5p and Pex14p. Alice Douangamath, et al.2002. Mol. Cell Topography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domain.