Gene : PEX25

Symbol :	PEX25
Name/description :	Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with homologous protein Pex27p Pex25p
Synonyms :
Organism :	Saccharomyces cerevisiae
Peroxisomal Localization :	GO: peroxisomal membrane Marcello Smith, et al.2002. J. Cell Biol. GFP: Won-Ki Huh, et al.2003. Nature Mass Spectrometry: No experiment found PeroxisomeDB annotation
Protein family :	PEX25-27
Protein consensus sequence :	MSQFGTTDIVSGSETPPYSGASYQDAQDDNTHPHSSDAGAEKFSAGSGSESHTESSRSDDEDSQAKTKMVDNITILKYILDSLSGRDKLAKIIKYALDILKLFIEKSKRNLTVLDPSVLTYYTKILKNLTVKVALRHPITVIKVLLLSLLRNFDKKIDFISQQLSTFRYILRFGGTPFRVCSFLGKFNKTRKCNFQIDQIKKIWFNEASLREFLDLYYGIFDELDLLYKLKIWTNKSFYSFVSRQESLAWQYDILLSLKDHWLNLQSLQKRQLELEVQLKVQNNALLLSPILMHQAHKDDGSQSPIRKQLLNDLNVNNDAEVLIHKQLKAIKDEKTLVYLDIARLSFDCMANTSDILNLKTPKGTYAVLSLGSGLTGLVKLWITTKRSLCSSKD
Functional category(ies) :	Peroxisome biogenesis (peroxins) Peroxisome division-proliferation
Disease(s) :	No diseases found
Comparative genomics:	PTS prediction Blastp PsiBlast Alignment Phylogenetic tree [help] PhylomeDB
Gene Info:	Gene Summary (NCBI) Genome Browser (UCSC) Chromosomal Localization (NCBI) ENSEMBL Protein Properties (UCSC) Conserved Domains (NCBI) Orthologue Prediction (NCBI)
Pubmed:	Monica Fagarasanu, et al.2005. J. Cell Biol. Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae. Marcello Marelli, et al.2004. J. Cell Biol. Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane. Hanspeter Rottensteiner, et al.2003. Mol. Biol. Cell Conserved function of pex11p and the novel pex25p and pex27p in peroxisome biogenesis. Marcello Tam, et al.2003. Mol. Biol. Cell Pex11-related proteins in peroxisome dynamics: a role for the novel peroxin Pex27p in controlling peroxisome size and number in Saccharomyces cerevisiae. Vizeacoumar Vizeacoumar, et al.2003. J. Cell Biol. YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae.